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Sample records for harbor resonance model

  1. Coastal Harbors Modeling Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Coastal Harbors Modeling Facility is used to aid in the planning of harbor development and in the design and layout of breakwaters, absorbers, etc.. The goal is...

  2. Modeling of Tsunami Currents in Harbors

    Science.gov (United States)

    Lynett, P. J.

    2010-12-01

    Extreme events, such as large wind waves and tsunamis, are well recognized as a damaging hazard to port and harbor facilities. Wind wave events, particularly those with long period spectral components or infragravity wave generation, can excite resonance inside harbors leading to both large vertical motions and strong currents. Tsunamis can cause great damage as well. The geometric amplification of these very long waves can create large vertical motions in the interior of a harbor. Additionally, if the tsunami is composed of a train of long waves, which it often is, resonance can be easily excited. These long wave motions create strong currents near the node locations of resonant motions, and when interacting with harbor structures such as breakwaters, can create intense turbulent rotational structures, typical in the form of large eddies or gyres. These gyres have tremendous transport potential, and have been observed to break mooring lines, and even cause ships to be trapped inside the rotation, moving helplessly with the flow until collision, grounding, or dissipation of the eddy (e.g. Okal et al., 2006). This presentation will introduce the traditional theory used to predict wave impacts on harbors, discussing both how these models are practically useful and in what types of situations require a more accurate tool. State-of-the-art numerical models will be introduced, with a focus on recent developments in Boussinesq-type modeling. The Boussinesq equations model can account the dispersive, turbulent and rotational flow properties frequently observed in nature. Also they have the ability to coupling currents and waves and can predict nonlinear wave propagation over uneven bottom from deep (or intermediate) water area to shallow water area. However, during the derivation of a 2D-horizontal equation set, some 3D flow features, such those driven by as the dispersive stresses and the effects of the unresolved small scale 3D turbulence, are excluded. Consequently

  3. Bar Harbor, ME Tsunami Forecast Grids for MOST Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Bar Harbor, Maine Forecast Model Grids provides bathymetric data strictly for tsunami inundation modeling with the Method of Splitting Tsunami (MOST) model. MOST...

  4. Apra Harbor, Guam Tsunami Forecast Grids for MOST Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Apra Harbor, Guam Forecast Model Grids provides bathymetric data strictly for tsunami inundation modeling with the Method of Splitting Tsunami (MOST) model. MOST...

  5. Pearl Harbor, Hawaii Tsunami Forecast Grids for MOST Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Pearl Harbor, Hawaii Forecast Model Grids provides bathymetric data strictly for tsunami inundation modeling with the Method of Splitting Tsunami (MOST) model....

  6. Impact of Geomorphological Changes to Harbor Resonance During Meteotsunamis: The Vela Luka Bay Test Case

    Science.gov (United States)

    Denamiel, Cléa; Šepić, Jadranka; Vilibić, Ivica

    2018-05-01

    In engineering studies, harbor resonance, including quality and amplification factors, is typically computed for swell and waves with periods shorter than 10 min. However, in various locations around the world, such as Vela Luka Bay in Croatia, meteotsunami waves of periods greater than 10 min can excite the bay or harbor natural modes and produce substantial structural damages. In this theoretical study, the impact of some geomorphological changes of Vela Luka Bay—i.e. deepening of the bay, dredging the harbor, adding a pier or a marina—to the amplification of the meteotsunami waves are presented for a set of 6401 idealized pressure wave field forcing used to derive robust statistics. The most substantial increase in maximum elevation is found when the Vela Luka harbor is dredged to a 5 m depth, which is in contradiction with the calculation of the quality factor showing a decrease of the harbor natural resonance. It has been shown that the forcing energy content at different frequency bands should also be taken into account when estimating the quality and amplification factors, as their typical definitions derived from the peak frequency of the sea level spectrum fail to represent the harbor response during meteotsunami events. New definitions of these factors are proposed in this study and are shown to be in good agreement with the results of the statistical analysis of the Vela Luka Bay maximum elevation results. In addition, the presented methodology can easily be applicable to any other location in the world where meteotsunamis occur.

  7. Dutch Harbor, Alaska Coastal Digital Elevation Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA's National Geophysical Data Center (NGDC) is building high-resolution digital elevation models (DEMs) for select U.S. coastal regions. These integrated...

  8. Hydraulic modeling of stream channels and structures in Harbor and Crow Hollow Brooks, Meriden, Connecticut

    Science.gov (United States)

    Weiss, Lawrence A.; Sears, Michael P.; Cervione, Michael A.

    1994-01-01

    Effects of urbanization have increased the frequency and size of floods along certain reaches of Harbor Brook and Crow Hollow Brook in Meriden, Conn. A floodprofile-modeling study was conducted to model the effects of selected channel and structural modifications on flood elevations and inundated areas. The study covered the reach of Harbor Brook downstream from Interstate 691 and the reach of Crow Hollow Brook downstream from Johnson Avenue. Proposed modifications, which include changes to bank heights, channel geometry, structural geometry, and streambed armoring on Harbor Brook and changes to bank heights on Crow Hollow Brook, significantly lower flood elevations. Results of the modeling indicate a significant reduction of flood elevations for the 10-year, 25-year, 35-year, 50-year, and 100-year flood frequencies using proposed modifications to (1 ) bank heights between Harbor Brook Towers and Interstate 691 on Harbor Brook, and between Centennial Avenue and Johnson Avenue on Crow Hollow Brook; (2) channel geometry between Coe Avenue and Interstate 69 1 on Harbor Brook; (3) bridge and culvert opening geometry between Harbor Brook Towers and Interstate 691 on Harbor Brook; and (4) channel streambed armoring between Harbor Brook Towers and Interstate 691 on Harbor Brook. The proposed modifications were developed without consideration of cost-benefit ratios.

  9. Analyzing Approaches to Internet Jurisdiction Based on Model of Harbors and the High Seas

    NARCIS (Netherlands)

    Jiménez, W.G.; Lodder, A.R.

    2015-01-01

    The inherent cross-border nature of the internet has challenged the legal system for over two decades. In this paper we introduce a model in which the internet is approached as if it were the high seas, the harbor of origin, the harbor of destination, or a combination of these. This model is used to

  10. MODELING HOW A HURRICANE BARRIER IN NEW BEDFORD HARBOR, MASSACHUSETTS, AFFECTS THE HYDRODYNAMICS AND RESIDENCE TIMES

    Science.gov (United States)

    Two-dimensional hydrodynamic and transport models were used to simulate tidal and subtidal circulation, residence times, and the longitudinal distributions of conservative constituents in New Bedford Harbor, Massachusetts, before and after a hurricane barrier was constructed. The...

  11. Model for resonant plasma probe.

    Energy Technology Data Exchange (ETDEWEB)

    Warne, Larry Kevin; Johnson, William Arthur; Hebner, Gregory Albert; Jorgenson, Roy E.; Coats, Rebecca Sue

    2007-04-01

    This report constructs simple circuit models for a hairpin shaped resonant plasma probe. Effects of the plasma sheath region surrounding the wires making up the probe are determined. Electromagnetic simulations of the probe are compared to the circuit model results. The perturbing effects of the disc cavity in which the probe operates are also found.

  12. Observations and modeling of tsunami-induced currents in ports and harbors

    Science.gov (United States)

    Lynett, Patrick J.; Borrero, Jose C.; Weiss, Robert; Son, Sangyoung; Greer, Dougal; Renteria, Willington

    2012-04-01

    Tsunamis, or "harbor waves" in Japanese, are so-named due to common observations of enhanced wave heights, currents and damage in harbors and ports. However, dynamic currents induced by these waves, while regularly observed and known to cause significant damage, are poorly understood. Observations and modeling of the currents induced by the 2011 Tohoku and 2004 Indian Ocean tsunamis allows us to show that the strongest flows in harbor basins are governed by horizontally sheared and rotational shallow features, such as jets and large eddies. When examining currents in harbors, this conclusion will generally require a simulation approach that both includes the relevant physical processes in the governing equations and uses a numerical scheme that does not artificially damp these features. Without proper representation of the physics associated with these phenomena, predictive models may provide drag force estimates that are an order of magnitude or more in error. The immediate implementation of this type of analysis into tsunami hazard studies can mean the difference between an unaffected port and one in which 300 m long container vessels are detached from their moorings and drift chaotically.

  13. Geometrical optics model of Mie resonances

    Science.gov (United States)

    Roll; Schweiger

    2000-07-01

    The geometrical optics model of Mie resonances is presented. The ray path geometry is given and the resonance condition is discussed with special emphasis on the phase shift that the rays undergo at the surface of the dielectric sphere. On the basis of this model, approximate expressions for the positions of first-order resonances are given. Formulas for the cavity mode spacing are rederived in a simple manner. It is shown that the resonance linewidth can be calculated regarding the cavity losses. Formulas for the mode density of Mie resonances are given that account for the different width of resonances and thus may be adapted to specific experimental situations.

  14. Assessment of a combination between hard structures and sand nourishment eastern of Damietta harbor using numerical modeling

    Directory of Open Access Journals (Sweden)

    A.M. Khalifa

    2017-12-01

    Full Text Available Damietta harbor was constructed in 1982 as an inland harbor with its 15 m depth navigation channel and two jetties acting like an obstacle to not allow sediment deposition in the harbor. On the other hand, they significantly affect the northern coast shoreline and hinder the sediment circulation in Damietta promontory. Satellite images show that new headlands are being implemented in the coastal shores of As-senaneyah. The proposed project consists of implementation of four headlands with length of 160 m, spacing of 400 m and using 150,000 m3 nourishment in those spacing between the hard structures only once during the construction time. Litpack 1D-model is used to predict shoreline responses to number of different five scenarios considered as combination between hard structures such as headlands and sand nourishment. A total number of 32 profiles were used to assess the shoreline changes along Gamasa, Damietta and Ras El-bar resort from 2010 to 2015. This study prevails a high erosion rate of the eastern and western shorelines of the proposed headlands. Nourishment of 200,000 m3/year is found to be a reasonable solution due to simplicity of being attained from Damietta harbor’s annual dredged materials which was reported to be average of 1 million m3/year. Keywords: Numerical modeling, Damietta harbor, Egyptian shoreline changes, Inland harbor

  15. Modeling of supermodes in coupled unstable resonators

    International Nuclear Information System (INIS)

    Townsend, S.S.

    1986-01-01

    A general formalism describing the supermodes of an array of N identical, circulantly coupled resonators is presented. The symmetry of the problem results in a reduction of the N coupled integral equations to N decoupled integral equations. Each independent integral equation defines a set of single-resonator modes derived for a hypothetical resonator whose geometry resembles a member of the real array with the exception that all coupling beams are replaced by feedback beams, each with a prescribed constant phase. A given array supermode consists of a single equivalent resonator mode appearing repetitively in each resonator with a prescribed relative phase between individual resonators. The specific array design chosen for example is that of N adjoint coupled confocal unstable resonators. The impact of coupling on the computer modeling of this system is discussed and computer results for the cases of two- and four-laser coupling are presented

  16. High Resolution Tsunami Modeling and Assessment of Harbor Resilience; Case Study in Istanbul

    Science.gov (United States)

    Cevdet Yalciner, Ahmet; Aytore, Betul; Gokhan Guler, Hasan; Kanoglu, Utku; Duzgun, Sebnem; Zaytsev, Andrey; Arikawa, Taro; Tomita, Takashi; Ozer Sozdinler, Ceren; Necmioglu, Ocal; Meral Ozel, Nurcan

    2014-05-01

    Ports and harbors are the major vulnerable coastal structures under tsunami attack. Resilient harbors against tsunami impacts are essential for proper, efficient and successful rescue operations and reduction of the loss of life and property by tsunami disasters. There are several critical coastal structures as such in the Marmara Sea. Haydarpasa and Yenikapi ports are located in the Marmara Sea coast of Istanbul. These two ports are selected as the sites of numerical experiments to test their resilience under tsunami impact. Cargo, container and ro-ro handlings, and short/long distance passenger transfers are the common services in both ports. Haydarpasa port has two breakwaters with the length of three kilometers in total. Yenikapi port has one kilometer long breakwater. The accurate resilience analysis needs high resolution tsunami modeling and careful assessment of the site. Therefore, building data with accurate coordinates of their foot prints and elevations are obtained. The high resolution bathymetry and topography database with less than 5m grid size is developed for modeling. The metadata of the several types of structures and infrastructure of the ports and environs are processed. Different resistances for the structures/buildings/infrastructures are controlled by assigning different friction coefficients in a friction matrix. Two different tsunami conditions - high expected and moderate expected - are selected for numerical modeling. The hybrid tsunami simulation and visualization codes NAMI DANCE, STOC-CADMAS System are utilized to solve all necessary tsunami parameters and obtain the spatial and temporal distributions of flow depth, current velocity, inundation distance and maximum water level in the study domain. Finally, the computed critical values of tsunami parameters are evaluated and structural performance of the port components are discussed in regard to a better resilience. ACKNOWLEDGEMENTS: Support by EU 603839 ASTARTE Project, UDAP-Ç-12

  17. Numerical Modeling of Wave Overtopping of Buffalo Harbor Confined Disposal Facility (CDF4)

    Science.gov (United States)

    2017-10-01

    navigation channel , and harbor complex. Though there are anecdotal claims and debris indicating possible sediment movement, there has been no evidence of...littoral sediments inside the disposal area, into the channel and harbor, and other adjacent areas to the CDF4. 1.4 Study plan 1.4.1 Purpose There...locations. 2.4 Maintenance dredging data The need for maintenance dredging arises from sedimentation in the navigation channels , which impedes

  18. Hyperon resonances in SU(3) soliton models

    International Nuclear Information System (INIS)

    Scoccola, N.N.

    1990-01-01

    Hyperon resonances excited in kaon-nucleon scattering are investigated in the framework of an SU(3) soliton model in which kaon degrees of freedom are treated as small fluctuations around an SU(2) soliton. For partial waves l≥2 the model predicts correctly the quantum numbers and average excitation energies of most of the experimentally observed Λ and Σ resonances. Some disagreements are found for lower partial waves. (orig.)

  19. Virulence of Klebsiella pneumoniae isolates harboring bla KPC-2 carbapenemase gene in a Caenorhabditis elegans model.

    Directory of Open Access Journals (Sweden)

    Jean-Philippe Lavigne

    Full Text Available Klebsiella pneumoniae carbapenemase (KPC is a carbapenemase increasingly reported worldwide in Enterobacteriaceae. The aim of this study was to analyze the virulence of several KPC-2-producing K. pneumoniae isolates. The studied strains were (i five KPC-2 clinical strains from different geographical origins, belonging to different ST-types and possessing plasmids of different incompatibility groups; (ii seven transformants obtained after electroporation of either these natural KPC plasmids or a recombinant plasmid harboring only the bla KPC-2 gene into reference strains K. pneumoniae ATCC10031/CIP53153; and (iii five clinical strains cured of plasmids. The virulence of K. pneumoniae isolates was evaluated in the Caenorhabditis elegans model. The clinical KPC producers and transformants were significantly less virulent (LT50: 5.5 days than K. pneumoniae reference strain (LT50: 4.3 days (p<0.01. However, the worldwide spread KPC-2 positive K. pneumoniae ST258 strains and reference strains containing plasmids extracted from K. pneumoniae ST258 strains had a higher virulence than KPC-2 strains belonging to other ST types (LT50: 5 days vs. 6 days, p<0.01. The increased virulence observed in cured strains confirmed this trend. The bla KPC-2 gene itself was not associated to increased virulence.

  20. [Pearl Harbor.

    Science.gov (United States)

    Johnson, Jennifer, Ed.

    1992-01-01

    This issue of "Loblolly Magazine" was written in observance of the 50th anniversary of the U.S. entrance into World War II. The publication features interviews conducted by East Texas high school students with Clarence Otterman, one of the few survivors of the crew of the USS Arizona, which was bombed during the attack on Pearl Harbor,…

  1. Predicting dredging-associated effects to coral reefs in Apra Harbor, Guam - Part 1: Sediment exposure modeling.

    Science.gov (United States)

    Gailani, Joseph Z; Lackey, Tahirih C; King, David B; Bryant, Duncan; Kim, Sung-Chan; Shafer, Deborah J

    2016-03-01

    Model studies were conducted to investigate the potential coral reef sediment exposure from dredging associated with proposed development of a deepwater wharf in Apra Harbor, Guam. The Particle Tracking Model (PTM) was applied to quantify the exposure of coral reefs to material suspended by the dredging operations at two alternative sites. Key PTM features include the flexible capability of continuous multiple releases of sediment parcels, control of parcel/substrate interaction, and the ability to efficiently track vast numbers of parcels. This flexibility has facilitated simulating the combined effects of sediment released from clamshell dredging and chiseling within Apra Harbor. Because the rate of material released into the water column by some of the processes is not well understood or known a priori, the modeling approach was to bracket parameters within reasonable ranges to produce a suite of potential results from multiple model runs. Sensitivity analysis to model parameters is used to select the appropriate parameter values for bracketing. Data analysis results include mapping the time series and the maximum values of sedimentation, suspended sediment concentration, and deposition rate. Data were used to quantify various exposure processes that affect coral species in Apra Harbor. The goal of this research is to develop a robust methodology for quantifying and bracketing exposure mechanisms to coral (or other receptors) from dredging operations. These exposure values were utilized in an ecological assessment to predict effects (coral reef impacts) from various dredging scenarios. Copyright © 2015. Published by Elsevier Ltd.

  2. Stochastic resonance in models of neuronal ensembles

    International Nuclear Information System (INIS)

    Chialvo, D.R.; Longtin, A.; Mueller-Gerkin, J.

    1997-01-01

    Two recently suggested mechanisms for the neuronal encoding of sensory information involving the effect of stochastic resonance with aperiodic time-varying inputs are considered. It is shown, using theoretical arguments and numerical simulations, that the nonmonotonic behavior with increasing noise of the correlation measures used for the so-called aperiodic stochastic resonance (ASR) scenario does not rely on the cooperative effect typical of stochastic resonance in bistable and excitable systems. Rather, ASR with slowly varying signals is more properly interpreted as linearization by noise. Consequently, the broadening of the open-quotes resonance curveclose quotes in the multineuron stochastic resonance without tuning scenario can also be explained by this linearization. Computation of the input-output correlation as a function of both signal frequency and noise for the model system further reveals conditions where noise-induced firing with aperiodic inputs will benefit from stochastic resonance rather than linearization by noise. Thus, our study clarifies the tuning requirements for the optimal transduction of subthreshold aperiodic signals. It also shows that a single deterministic neuron can perform as well as a network when biased into a suprathreshold regime. Finally, we show that the inclusion of a refractory period in the spike-detection scheme produces a better correlation between instantaneous firing rate and input signal. copyright 1997 The American Physical Society

  3. The sympletic model for giant monopole resonances

    International Nuclear Information System (INIS)

    Oliveira, M.M.B.M.

    1985-01-01

    Following recently published articles, it's investigated how to apply the sympletic model to the study of giant monopole resonances in spherical nuclei. The results obtained agree with those already published for monopole mode energies, wave functions, radii and nuclear incompressibility of 16 O and 40 Ca nuclei. An analyse of how the spurious center-of-mass motion influence resonance energies is made. The sum rules of the monopole operator, m-bar e , o ≤ e ≤ 3, are calculated, demonstrating at first that they are conserved in the sympletic model. Then it's studied, for those sum rules, the importance of n-boson correlations in the fundamental state, which is an extension of those sum rules, of the analysis for the nuclear incompressibility, performed in above mentioned articles. (Author) [pt

  4. Frequency Domain Response at Pacific Coast Harbors to Major Tsunamis of 2005-2011

    Science.gov (United States)

    Xing, Xiuying; Kou, Zhiqing; Huang, Ziyi; Lee, Jiin-Jen

    2013-06-01

    Tsunamis waves caused by submarine earthquake or landslide might contain large wave energy, which could cause significant human loss and property damage locally as well as in distant region. The response of three harbors located at the Pacific coast (i.e. Crescent City Harbor, Los Angeles/Long Beach Port, and San Diego Harbor) to six well-known tsunamis events generated (both near-field and far-field) between 2005 and 2011 are examined and simulated using a hybrid finite element numerical model in frequency domain. The model incorporated the effects of wave refraction, wave diffraction, partial wave reflection from boundaries, entrance and bottom energy dissipation. It can be applied to harbor regions with arbitrary shapes and variable water depth. The computed resonant periods or modes of oscillation for three harbors are in good agreement with the energy spectral analysis of the time series of water surface elevations recorded at tide gauge stations inside three harbors during the six tsunamis events. The computed wave induced currents based on the present model are also in qualitative agreement with some of the reported eye-witness accounts absence of reliable current data. The simulated results show that each harbor responded differently and significantly amplified certain wave period(s) of incident wave trains according to the shape, topography, characteristic dimensions and water depth of the harbor basins.

  5. A non-invasive approach to study lifetime exposure and bioaccumulation of PCBs in protected marine mammals: PBPK modeling in harbor porpoises

    International Nuclear Information System (INIS)

    Weijs, Liesbeth; Covaci, Adrian; Yang, Raymond S.H.; Das, Krishna; Blust, Ronny

    2011-01-01

    In the last decade, physiologically based pharmacokinetic (PBPK) models have increasingly been developed to explain the kinetics of environmental pollutants in wildlife. For marine mammals specifically, these models provide a new, non-destructive tool that enables the integration of biomonitoring activities and in vitro studies. The goals of the present study were firstly to develop PBPK models for several environmental relevant PCB congeners in harbor porpoises (Phocoena phocoena), a species that is sensitive to pollution because of its limited metabolic capacity for pollutant transformation. These models were tested using tissue data of porpoises from the Black Sea. Secondly, the predictive power of the models was investigated for time trends in the PCB concentrations in North Sea harbor porpoises between 1990 and 2008. Thirdly, attempts were made to assess metabolic capacities of harbor porpoises for the investigated PCBs. In general, results show that parameter values from other species (rodents, humans) are not always suitable in marine mammal models, most probably due to differences in physiology and exposure. The PCB 149 levels decrease the fastest in male harbor porpoises from the North Sea in a time period of 18 years, whereas the PCB 101 levels decrease the slowest. According to the models, metabolic breakdown of PCB 118 is probably of lesser importance compared to other elimination pathways. For PCB 101 and 149 however, the presence of their metabolites can be attributed to bioaccumulation of metabolites from the prey and to metabolic breakdown of the parent compounds in the harbor porpoises. - Highlights: → PBPK modeling was used to study the kinetics of several PCBs in a marine mammal. → Harbor porpoises are sensitive to pollution and therefore ideal model organisms. → Black Sea data were used for parameterization. → North Sea data for assessing temporal trends (1990-2008). → PBPK modeling is a non-invasive and non-destructive tool.

  6. Modeling and analysis of a resonant nanosystem

    Science.gov (United States)

    Calvert, Scott L.

    The majority of investigations into nanoelectromechanical resonators focus on a single area of the resonator's function. This focus varies from the development of a model for a beam's vibration, to the modeling of electrostatic forces, to a qualitative explanation of experimentally-obtained currents. Despite these efforts, there remains a gap between these works, and the level of sophistication needed to truly design nanoresonant systems for efficient commercial use. Towards this end, a comprehensive system model for both a nanobeam resonator and its related experimental setup is proposed. Furthermore, a simulation arrangement is suggested as a method for facilitating the study of the system-level behavior of these devices in a variety of cases that could not be easily obtained experimentally or analytically. The dynamics driving the nanoresonator's motion, as well as the electrical interactions influencing the forcing and output of the system, are modeled, experimentally validated, and studied. The model seeks to develop both a simple circuit representation of the nanoresonator, and to create a mathematical system that can be used to predict and interpret the observed behavior. Due to the assumptions used to simplify the model to a point of reasonable comprehension, the model is most accurate for small beam deflections near the first eigenmode of the beam. The process and results of an experimental investigation are documented, and compared with a circuit simulation modeling the full test system. The comparison qualitatively proves the functionality of the model, while a numerical analysis serves to validate the functionality and setup of the circuit simulation. The use of the simulation enables a much broader investigation of both the electrical behavior and the physical device's dynamics. It is used to complement an assessment of the tuning behavior of the system's linear natural frequency by demonstrating the tuning behavior of the full nonlinear response. The

  7. Isoscalar giant resonances in a relativistic model

    International Nuclear Information System (INIS)

    L'Huillier, M.; Nguyen Van Giai.

    1988-07-01

    Isoscalar giant resonances in finite nuclei are studied in a relativistic Random Phase Approximation (RRPA) approach. The model is self-consistent in the sense that one set of coupling constants generates the Dirac-Hartree single-particle spectrum and the residual particle-hole interaction. The RRPA is used to calculate response functions of multipolarity L = 0,2,3, and 4 in light and medium nuclei. It is found that monopole and quadrupole modes exhibit a collective character. The peak energies are overestimated, but not as much as one might think if the bulk properties (compression modulus, effective mass) were the only relevant quantities

  8. Markov Chain Models for Stochastic Behavior in Resonance Overlap Regions

    Science.gov (United States)

    McCarthy, Morgan; Quillen, Alice

    2018-01-01

    We aim to predict lifetimes of particles in chaotic zoneswhere resonances overlap. A continuous-time Markov chain model isconstructed using mean motion resonance libration timescales toestimate transition times between resonances. The model is applied todiffusion in the co-rotation region of a planet. For particles begunat low eccentricity, the model is effective for early diffusion, butnot at later time when particles experience close encounters to the planet.

  9. Novel baryon resonances in the Skyrme model

    International Nuclear Information System (INIS)

    Hussain, F.; Sri Ram, M.S.

    1985-01-01

    We predict a novel family of baryons with or without the charm quantum number by quantizing the ''maximal solitons'' in the SU(4) Skyrme model. The baryon number B of these solitons can take any integer value. The low-lying states with B = 1 belong to 4( with spin (3/2), 20( with spin (1/2), (3/2), (5/2), or (7/2), and 20('' with spin (3/2), (5/2), or (9/2). The charm-zero states among them could correspond to some of the observed resonances in meson-baryon scattering between 1.5--2 GeV. The lowest among the dibaryon states is an SU(3) singlet contained in the 10( of SU(4) with spin 1, with mass in the range 2.5--3 GeV

  10. Bar Harbor, Maine 1/3 Arc-second MWH Coastal Digital Elevation Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA's National Geophysical Data Center (NGDC) is building high-resolution digital elevation models (DEMs) for select U.S. coastal regions. These integrated...

  11. Bar Harbor, Maine 1/3 Arc-second NAVD 88 Coastal Digital Elevation Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA's National Geophysical Data Center (NGDC) is building high-resolution digital elevation models (DEMs) for select U.S. coastal regions. These integrated...

  12. Transgenic Mouse Model Harboring the Transcriptional Fusion Ccl20-Luciferase as a Novel Reporter of Pro-Inflammatory Response

    Science.gov (United States)

    Crispo, Martina; Van Maele, Laurye; Tabareau, Julien; Cayet, Delphine; Errea, Agustina; Ferreira, Ana María; Rumbo, Martin; Sirard, Jean Claude

    2013-01-01

    The chemokine CCL20, the unique ligand of CCR6 functions as an attractant of immune cells. Expression of CCL20 is induced by Toll-like Receptor (TLR) signaling or proinflammatory cytokine stimulation. However CCL20 is also constitutively produced at specific epithelial sites of mucosa. This expression profile is achieved by transcriptional regulation. In the present work we characterized regulatory features of mouse Ccl20 gene. Transcriptional fusions between the mouse Ccl20 promoter and the firefly luciferase (luc) encoding gene were constructed and assessed in in vitro and in vivo assays. We found that liver CCL20 expression and luciferase activity were upregulated by systemic administration of the TLR5 agonist flagellin. Using shRNA and dominant negative form specific for mouse TLR5, we showed that this expression was controlled by TLR5. To address in situ the regulation of gene activity, a transgenic mouse line harboring a functional Ccl20-luc fusion was generated. The luciferase expression was highly concordant with Ccl20 expression in different tissues. Our data indicate that the transgenic mouse model can be used to monitor activation of innate response in vivo. PMID:24265691

  13. Dual resonance models and their currents

    International Nuclear Information System (INIS)

    Johnson, E.A.

    1978-01-01

    It is shown how dual resonance models were rederived from the concept of a string tracing out a surface in space-time. Thus, interacting strings reproduce the dual amplitudes. A scheme for tackling the unitarity problem began to develop. As a consistent theory of hadronic processes began to be built, workers at the same time were naturally led to expect that leptons could be included with hadrons in a unified dual theory. Thus, there is a search for dual amplitudes which would describe interactions between hadrons and currents (for example, electrons), as well as interactions involving only hadrons. Such amplitudes, it is believed, will be the correct ones, describing the real world. Such amplitudes will provide valuable information concerning such things as hadronic form factors. The great difficulties in building current-amplitudes with the required properties of proper factorization on a good spectrum, duality, current algebra, and proper asymptotic behavior are described. Dual models at the present time require for consistency, an intercept value of α 0 = 1 and a dimension value of d = 26 (or d = 10). There have been speculations that the unphysical dimension may be made physical by associating the ''extra dimensions'' with certain internal degrees of freedom. However, it is desired that the theory itself, force the dimension d = 4. It is quite possible that the dimension problem and the intercept problem are tied together and that resolving either problem will resolve the other. Order by order, a new dual current is constructed that is manifestly factorizable and which appears to be valid for arbitrary space-time dimension. The fact that this current is not bound at d = 26, leads to interesting speculations on the nature of dual currents

  14. Modeling of nanofabricated paddle bridges for resonant mass sensing

    International Nuclear Information System (INIS)

    Lobontiu, N.; Ilic, B.; Garcia, E.; Reissman, T.; Craighead, H. G.

    2006-01-01

    The modeling of nanopaddle bridges is studied in this article by proposing a lumped-parameter mathematical model which enables structural characterization in the resonant domain. The distributed compliance and inertia of all three segments composing a paddle bridge are taken into consideration in order to determine the equivalent lumped-parameter stiffness and inertia fractions, and further on the bending and torsion resonant frequencies. The approximate model produces results which are confirmed by finite element analysis and experimental measurements. The model is subsequently utilized to quantify the amount of mass which attaches to the bridge by predicting the modified resonant frequencies in either bending or torsion

  15. Chrystal and Proudman resonances simulated with three numerical models

    Science.gov (United States)

    Bubalo, Maja; Janeković, Ivica; Orlić, Mirko

    2018-05-01

    The aim of this work was to study Chrystal and Proudman resonances in a simple closed basin and to explore and compare how well the two resonant mechanisms are reproduced with different, nowadays widely used, numerical ocean models. The test case was based on air pressure disturbances of two commonly used shapes (a sinusoidal and a boxcar), having various wave lengths, and propagating at different speeds. Our test domain was a closed rectangular basin, 300 km long with a uniform depth of 50 m, with the theoretical analytical solution available for benchmark. In total, 2250 simulations were performed for each of the three different numerical models: ADCIRC, SCHISM and ROMS. During each of the simulations, we recorded water level anomalies and computed the integral of the energy density spectrum for a number of points distributed along the basin. We have successfully documented the transition from Proudman to Chrystal resonance that occurs for a sinusoidal air pressure disturbance having a wavelength between one and two basin lengths. An inter-model comparison of the results shows that different models represent the two resonant phenomena in a slightly different way. For Chrystal resonance, all the models showed similar behavior; however, ADCIRC model providing slightly higher values of the mean resonant period than the other two models. In the case of Proudman resonance, the most consistent results, closest to the analytical solution, were obtained using ROMS model, which reproduced the mean resonant speed equal to 22.00 m/s— i.e., close to the theoretical value of 22.15 m/s. ADCIRC and SCHISM models showed small deviations from that value, with the mean speed being slightly lower—21.97 m/s (ADCIRC) and 21.93 m/s (SCHISM). The findings may seem small but could play an important role when resonance is a crucial process producing enhancing effects by two orders of magnitude (i.e., meteotsunamis).

  16. Entanglement Evolution of Jaynes-Cummings Model in Resonance Case and Non-resonance Case

    Science.gov (United States)

    Cheng, Jing; Chen, Xi; Shan, Chuan-Jia

    2018-03-01

    We investigate the entanglement evolution of a two-level atom and a quantized single model electromagnetic filed in the resonance and non-resonance cases. The effects of the initial state, detuning degree, photon number on the entanglement are shown in detail. The results show that the atom-cavity entanglement state appears with periodicity. The increasing of the photon number can make the period of quantum entanglement be shorter. In the non-resonant case, if we choose the suitable initial state the entanglement of atom-cavity can be 1.0

  17. The Friedrichs model and its use in resonance phenomena

    Energy Technology Data Exchange (ETDEWEB)

    Gadella, M. [Departamento de Fisica Teorica, Atomica y Optica, Facultad de Ciencias, 47071 Valladolid (Spain); Pronko, G.P. [Institute for High Energy Physics, Protvino 142284, Moscow Region (Russian Federation)

    2011-09-15

    We present here a relation of different types of Friedrichs models and their use in the description and comprehension of resonance phenomena. We first discuss the basic Friedrichs model and obtain its resonance in the case that this is simple or doubly degenerated. Next, we discuss the model with N levels and show how the probability amplitude has an oscillatory behavior. Two generalizations of the Friedrichs model are suitable to introduce resonance behavior in quantum field theory. We also discuss a discrete version of the Friedrichs model and also a resonant interaction between two systems both with continuous spectrum. In an appendix, we review the mathematics of rigged Hilbert spaces. (Copyright copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  18. Analytical Model of Planar Double Split Ring Resonator

    DEFF Research Database (Denmark)

    Zhurbenko, Vitaliy; Jensen, Thomas; Krozer, Viktor

    2007-01-01

    This paper focuses on accurate modelling of microstrip double split ring resonators. The impedance matrix representation for coupled lines is applied for the first time to model the SRR, resulting in excellent model accuracy over a wide frequency range. Phase compensation is implemented to take i...

  19. Semi classical model of the neutron resonance compound nucleus

    International Nuclear Information System (INIS)

    Ohkubo, Makio

    1995-01-01

    A Semi-classical model of compound nucleus is developed, where time evolution and recurrence for many degrees of freedom (oscillators) excited simultaneously are explicitly considered. The effective number of oscillators plays the role in the compound nucleus, and the nuclear temperatures are derived, which are in good agreement with the traditional values. Time structures of the compound nucleus at resonance are considered, from which equidistant level series with an envelope of strength function of giant resonance nature is obtained. S-matrix formulation for fine structure resonance is derived. (author)

  20. Validation of an Acoustic Impedance Prediction Model for Skewed Resonators

    Science.gov (United States)

    Howerton, Brian M.; Parrott, Tony L.

    2009-01-01

    An impedance prediction model was validated experimentally to determine the composite impedance of a series of high-aspect ratio slot resonators incorporating channel skew and sharp bends. Such structures are useful for packaging acoustic liners into constrained spaces for turbofan noise control applications. A formulation of the Zwikker-Kosten Transmission Line (ZKTL) model, incorporating the Richards correction for rectangular channels, is used to calculate the composite normalized impedance of a series of six multi-slot resonator arrays with constant channel length. Experimentally, acoustic data was acquired in the NASA Langley Normal Incidence Tube over the frequency range of 500 to 3500 Hz at 120 and 140 dB OASPL. Normalized impedance was reduced using the Two-Microphone Method for the various combinations of channel skew and sharp 90o and 180o bends. Results show that the presence of skew and/or sharp bends does not significantly alter the impedance of a slot resonator as compared to a straight resonator of the same total channel length. ZKTL predicts the impedance of such resonators very well over the frequency range of interest. The model can be used to design arrays of slot resonators that can be packaged into complex geometries heretofore unsuitable for effective acoustic treatment.

  1. Hybrid model for the decay of nuclear giant resonances

    International Nuclear Information System (INIS)

    Hussein, M.S.

    1986-12-01

    The decay properties of nuclear giant multipole resonances are discussed within a hybrid model that incorporates, in a unitary consistent way, both the coherent and statistical features. It is suggested that the 'direct' decay of the GR is described with continuum first RPA and the statistical decay calculated with a modified Hauser-Feshbach model. Application is made to the decay of the giant monopole resonance in 208 Pb. Suggestions are made concerning the calculation of the mixing parameter using the statistical properties of the shell model eigenstates at high excitation energies. (Author) [pt

  2. Relativistic Coulomb excitation of giant resonances in the hydrodynamic model

    International Nuclear Information System (INIS)

    Vasconcellos Gomes, Ana Cristina de.

    1990-05-01

    We investigate the Coulomb excitation of giant dipole resonances in relativistic heavy ion collisions using a macroscopic hydrodynamical model for the harmonic vibrations of the nuclear fluid. The motion is treated as a combination of the Goldhaber-Teller displacement mode and the Steinwedel-Jensen acoustic mode, and the restoring forces are calculated using the droplet model. This model is used as input to study the characteristics of multiple excitation of giant dipole resonances in nuclei. Possible signatures for the existence of such states are also discussed quantitatively. (author). 52 refs., 14 figs., 3 tabs

  3. Nonlinear Dynamics of a Helicopter Model in Ground Resonance

    Science.gov (United States)

    Tang, D. M.; Dowell, E. H.

    1985-01-01

    An approximate theoretical method is presented which determined the limit cycle behavior of a helicopter model which has one or two nonlinear dampers. The relationship during unstable ground resonance oscillations between lagging motion of the blades and fuselage motion is discussed. An experiment was carried out on using a helicopter scale model. The experimental results agree with those of the theoretical analysis.

  4. Resonantly produced 7 keV sterile neutrino dark matter models and the properties of Milky Way satellites.

    Science.gov (United States)

    Abazajian, Kevork N

    2014-04-25

    Sterile neutrinos produced through a resonant Shi-Fuller mechanism are arguably the simplest model for a dark matter interpretation of the origin of the recent unidentified x-ray line seen toward a number of objects harboring dark matter. Here, I calculate the exact parameters required in this mechanism to produce the signal. The suppression of small-scale structure predicted by these models is consistent with Local Group and high-z galaxy count constraints. Very significantly, the parameters necessary in these models to produce the full dark matter density fulfill previously determined requirements to successfully match the Milky Way Galaxy's total satellite abundance, the satellites' radial distribution, and their mass density profile, or the "too-big-to-fail problem." I also discuss how further precision determinations of the detailed properties of the candidate sterile neutrino dark matter can probe the nature of the quark-hadron transition, which takes place during the dark matter production.

  5. Small-signal model for the series resonant converter

    Science.gov (United States)

    King, R. J.; Stuart, T. A.

    1985-01-01

    The results of a previous discrete-time model of the series resonant dc-dc converter are reviewed and from these a small signal dynamic model is derived. This model is valid for low frequencies and is based on the modulation of the diode conduction angle for control. The basic converter is modeled separately from its output filter to facilitate the use of these results for design purposes. Experimental results are presented.

  6. A dual resonance model for high energy electroweak reactions

    International Nuclear Information System (INIS)

    Picard, Jean-Francois

    1995-01-01

    The aim of this work is to propose an original model for the weak interaction at high energy (about 1 TeV) that is inspired from resonance dual models established for hadron physics. The first chapter details the basis and assumptions of the standard model. The second chapter deals with various scenarios that go beyond the standard model and that involve a strong interaction and a perturbative approach to assess coupling. The third chapter is dedicated to the main teachings of hadron physics concerning resonances, the model of Regge poles and the concept of duality. We present our new model in the fourth chapter, we build a scenario in which standard fermions and the 3 massive gauge bosons would have a sub-structure alike that of hadrons. In order to give non-null values to the width of resonances we use the K matrix method, we describe this method in the last chapter and we apply it for the computation of the width of the Z 0 boson. Our model predicts a large spectra of states particularly with the 143-up-lets of ff-bar states. The K matrix method has allowed us to compute amplitudes for helicity, then to collapse them in amplitudes invariant with SU(2) and to project these amplitudes in partial waves of helicity. For most resonances partial widths are very low compared to their mass

  7. Resonance

    DEFF Research Database (Denmark)

    Petersen, Nils Holger

    2014-01-01

    A chapter in a book about terminology within the field of medievalism: the chapter discusses the resonance of medieval music and ritual in modern (classical) music culture and liturgical practice.......A chapter in a book about terminology within the field of medievalism: the chapter discusses the resonance of medieval music and ritual in modern (classical) music culture and liturgical practice....

  8. Equivalent-circuit model for the thickness-shear mode resonator with a viscoelastic film near film resonance.

    Science.gov (United States)

    Martin, S J; Bandey, H L; Cernosek, R W; Hillman, A R; Brown, M J

    2000-01-01

    We derive a lumped-element, equivalent-circuit model for the thickness-shear mode (TSM) resonator with a viscoelastic film. This modified Butterworth-Van Dyke model includes in the motional branch a series LCR resonator, representing the quartz resonance, and a parallel LCR resonator, representing the film resonance. This model is valid in the vicinity of film resonance, which occurs when the acoustic phase shift across the film is an odd multiple of pi/2 rad. For low-loss films, this model accurately predicts the frequency changes and damping that arise at resonance and is a reasonable approximation away from resonance. Elements of the parallel LCR resonator are explicitly related to film properties and can be interpreted in terms of elastic energy storage and viscous power dissipation. The model leads to a simple graphical interpretation of the coupling between the quartz and film resonances and facilitates understanding of the resulting responses. These responses are compared with predictions from the transmission-line and Sauerbrey models.

  9. Modelling Strategies for Functional Magnetic Resonance Imaging

    DEFF Research Database (Denmark)

    Madsen, Kristoffer Hougaard

    2009-01-01

    and generalisations to higher order arrays are considered. Additionally, an application of the natural conjugate prior for supervised learning in the general linear model to efficiently incorporate prior information for supervised analysis is presented. Further extensions include methods to model nuisance effects...... in fMIR data thereby suppressing noise for both supervised and unsupervised analysis techniques....

  10. Giant resonance of electrical multipole from droplet model

    International Nuclear Information System (INIS)

    Tauhata, L.

    1984-01-01

    The formalism of the electrical multipole resonance developed from the Droplet nuclear model is presented. It combines the approaches of Goldhaber-Teller (GT) and Steinwedel-Jensen (SJ) and it shows the relative contribution of Coulomb, superficial and neutron excess energies. It also discusses the calculation of half-width. The model evaluates correctly the resonance energies as a function of nuclear mass and allows, through the Mixture Index, the prediction of the complementary participation of modes SJ and GT in the giant nuclear resonance. Values of the mixture index, for each multipolarity, reproduce well the form factors obtained from experiments of charged particle inelastic scattering. The formalism presented for the calculation of the half-width gives a macroscopic description of the friction mechanism. The establishment of the macroscopic structure of the Dissipation Function is used as a reference in the comparison of microscopic calculations. (Author) [pt

  11. RECONSTRUCTION OF HUMAN LUNG MORPHOLOGY MODELS FROM MAGNETIC RESONANCE IMAGES

    Science.gov (United States)

    Reconstruction of Human Lung Morphology Models from Magnetic Resonance ImagesT. B. Martonen (Experimental Toxicology Division, U.S. EPA, Research Triangle Park, NC 27709) and K. K. Isaacs (School of Public Health, University of North Carolina, Chapel Hill, NC 27514)

  12. The early years of string theory: The dual resonance model

    International Nuclear Information System (INIS)

    Ramond, P.

    1987-10-01

    This paper reviews the past quantum mechanical history of the dual resonance model which is an early string theory. The content of this paper is listed as follows: historical review, the Veneziano amplitude, the operator formalism, the ghost story, and the string story

  13. A non-static model for the Roper resonances

    International Nuclear Information System (INIS)

    Guichon, P.A.M.

    1985-07-01

    We solve the M.I.T. bag equations for Fermions in the limit of small fluctuations and quantize the solution. We get a non static bag model which provides a satisfactory interpretation of the Roper resonances if the time averaged radius of the cavitity is about 1 fm

  14. Modeling the full-bridge series-resonant power converter

    Science.gov (United States)

    King, R. J.; Stuart, T. A.

    1982-01-01

    A steady state model is derived for the full-bridge series-resonant power converter. Normalized parametric curves for various currents and voltages are then plotted versus the triggering angle of the switching devices. The calculations are compared with experimental measurements made on a 50 kHz converter and a discussion of certain operating problems is presented.

  15. The fusion rate in the transmission resonance model

    International Nuclear Information System (INIS)

    Jaendel, M.

    1992-01-01

    Resonant transmission of deuterons through a chain of target deuterons in a metal matrix has been suggested as an explanation for the cold fusion phenomena. In this paper the fusion rate in such transmission resonance models is estimated, and the basic physical constraints are discussed. The dominating contribution to the fusion yield is found to come from metastable states. The fusion rate is well described by the Wentzel-Kramer-Brillouin approximation and appears to be much too small to explain the experimental anomalies

  16. Parameter Identification for Nonlinear Circuit Models of Power BAW Resonator

    Directory of Open Access Journals (Sweden)

    CONSTANTINESCU, F.

    2011-02-01

    Full Text Available The large signal operation of the bulk acoustic wave (BAW resonators is characterized by the amplitude-frequency effect and the intermodulation effect. The measurement of these effects, together with that of the small signal frequency characteristic, are used in this paper for the parameter identification of the nonlinear circuit models developed previously by authors. As the resonator has been connected to the measurement bench by wire bonding, the parasitic elements of this connection have been taken into account, being estimated solving some electrical and magnetic field problems.

  17. Modelling Brain Tissue using Magnetic Resonance Imaging

    DEFF Research Database (Denmark)

    Dyrby, Tim Bjørn

    2008-01-01

    Diffusion MRI, or diffusion weighted imaging (DWI), is a technique that measures the restricted diffusion of water molecules within brain tissue. Different reconstruction methods quantify water-diffusion anisotropy in the intra- and extra-cellular spaces of the neural environment. Fibre tracking...... models then use the directions of greatest diffusion as estimates of white matter fibre orientation. Several fibre tracking algorithms have emerged in the last few years that provide reproducible visualizations of three-dimensional fibre bundles. One class of these algorithms is probabilistic...... the possibility of using high-field experimental MR scanners and long scanning times, thereby significantly improving the signal-to-noise ratio (SNR) and anatomical resolution. Moreover, many of the degrading effects observed in vivo, such as physiological noise, are no longer present. However, the post mortem...

  18. On the quark structure of resonance states in dual models

    International Nuclear Information System (INIS)

    Volkov, D.V.; Zheltukhin, A.A.; Pashnev, A.I.

    1975-01-01

    It is shown using as an example the Veneziano dual model, that each particular dual model already contains a certain latent quark structure unambiauously determined by internal properties of the dual model. To prove this degeneration of the resonance state spectrum is studied by introducing an additional disturbing interaction into the model being considered. Induced transitions of particles into a vacuum act as such an additional disturbance. This method complements the known factorization method of Fubini, Gordon and Veneziano and turns out to be free from an essential limitation of the latter connected with implicit assumption about the basence of internal additive laws of conservation in the model. By using the method of induced transitions of particles into a vacuum it has been possible to show that the resonance state spectrum is indeed more degenerated than it should be expected from the factorization theorem, and that the supplementary degeneration corresponds to the quark model with an infinite number of quarks of the increasing mass. Structures of some terms of the dual amplitude expansion over the degrees of the constant of the induced transition of particles to vacuum are considered; it is shown that the summation of this expansion may be reduced to a solution of a certain integral equation. On the basis of the integral equation obtained an integral representation ofr dual amplitudes is established. The problems related with degeneration of resonance states and with determination of additive quantum numbers leading to the quark interpretation of the degeneration being considered are discussed

  19. Resonances

    DEFF Research Database (Denmark)

    an impetus or drive to that account: change, innovation, rupture, or discontinuity. Resonances: Historical Essays on Continuity and Change explores the historiographical question of the modes of interrelation between these motifs in historical narratives. The essays in the collection attempt to realize...

  20. Conserved number fluctuations in a hadron resonance gas model

    International Nuclear Information System (INIS)

    Garg, P.; Mishra, D.K.; Netrakanti, P.K.; Mohanty, B.; Mohanty, A.K.; Singh, B.K.; Xu, N.

    2013-01-01

    Net-baryon, net-charge and net-strangeness number fluctuations in high energy heavy-ion collisions are discussed within the framework of a hadron resonance gas (HRG) model. Ratios of the conserved number susceptibilities calculated in HRG are being compared to the corresponding experimental measurements to extract information about the freeze-out condition and the phase structure of systems with strong interactions. We emphasize the importance of considering the actual experimental acceptances in terms of kinematics (pseudorapidity (η) and transverse momentum (p T )), the detected charge state, effect of collective motion of particles in the system and the resonance decay contributions before comparisons are made to the theoretical calculations. In this work, based on HRG model, we report that the net-baryon number fluctuations are least affected by experimental acceptances compared to the net-charge and net-strangeness number fluctuations

  1. The Droplet model of the Giant Fipole Resonance

    International Nuclear Information System (INIS)

    Myers, W.D.; Kodama, T.; El-Jaick, L.J.; Hilf, E.R.

    1976-10-01

    The nuclear Giant Dipole Resonance (GDR) energies are calculated using a macroscopic hydronamical model with two new features. The motion is treated as a combination of the usual Goldhaber-Teller (GT) and Steinwedel-Jensen (SJ) modes, and the restoring forces are all calculated using the Droplet Model. The A dependence of the resonance energies is well reproduced without any adjustable parameters, and the measured magnitude of the energies serves to fix the value of the effective mass m* used in the theory. The GDR is found to consist mainly of a GT-type motion with the SJ-mode becoming more important for heavy nuclei. The width P of the GDR is also estimated on the basis of an expression for one-body damping [pt

  2. Modeling laser brightness from cross Porro prism resonators

    Science.gov (United States)

    Forbes, Andrew; Burger, Liesl; Litvin, Igor Anatolievich

    2006-08-01

    Laser brightness is a parameter often used to compare high power laser beam delivery from various sources, and incorporates both the power contained in the particular mode, as well as the propagation of that mode through the beam quality factor, M2. In this study a cross Porro prism resonator is considered; crossed Porro prism resonators have been known for some time, but until recently have not been modeled as a complete physical optics system that allows the modal output to be determined as a function of the rotation angle of the prisms. In this paper we consider the diffraction losses as a function of the prism rotation angle relative to one another, and combine this with the propagation of the specific modes to determine the laser output brightness as a function of the prism orientation.

  3. Statistical Modelling of Resonant Cross Section Structure in URR, Model of the Characteristic Function

    International Nuclear Information System (INIS)

    Koyumdjieva, N.

    2006-01-01

    A statistical model for the resonant cross section structure in the Unresolved Resonance Region has been developed in the framework of the R-matrix formalism in Reich Moore approach with effective accounting of the resonance parameters fluctuations. The model uses only the average resonance parameters and can be effectively applied for analyses of cross sections functional, averaged over many resonances. Those are cross section moments, transmission and self-indication functions measured through thick sample. In this statistical model the resonant cross sections structure is accepted to be periodic and the R-matrix is a function of ε=E/D with period 0≤ε≤N; R nc (ε)=π/2√(S n *S c )1/NΣ(i=1,N)(β in *β ic *ctg[π(ε i - = ε-iS i )/N]; Here S n ,S c ,S i is respectively neutron strength function, strength function for fission or inelastic channel and strength function for radiative capture, N is the number of resonances (ε i ,β i ) that obey the statistic of Porter-Thomas and Wigner's one. The simple case of this statistical model concerns the resonant cross section structure for non-fissile nuclei under the threshold for inelastic scattering - the model of the characteristic function with HARFOR program. In the above model some improvements of calculation of the phases and logarithmic derivatives of neutron channels have been done. In the parameterization we use the free parameter R l ∞ , which accounts the influence of long-distant resonances. The above scheme for statistical modelling of the resonant cross section structure has been applied for evaluation of experimental data for total, capture and inelastic cross sections for 232 Th in the URR (4-150) keV and also the transmission and self-indication functions in (4-175) keV. The set of evaluated average resonance parameters have been obtained. The evaluated average resonance parameters in the URR are consistent with those in the Resolved Resonance Region (CRP for Th-U cycle, Vienna, 2006

  4. Rectifier Current Control for an LLC Resonant Converter Based on a Simplified Linearized Model

    OpenAIRE

    Zhijian Fang; Junhua Wang; Shanxu Duan; Liangle Xiao; Guozheng Hu; Qisheng Liu

    2018-01-01

    In this paper, a rectifier current control for an LLC resonant converter is proposed, based on a simplified, two-order, linearized model that adds a rectifier current feedback inner loop to improve dynamic performance. Compared to the traditional large-signal model with seven resonant states, this paper utilizes a rectifier current state to represent the characteristics of the resonant states, simplifying the LLC resonant model from seven orders to two orders. Then, the rectifier current feed...

  5. Applicability of numerical model for seabed topography changes by tsunami flow. Analysis of formulae for sediment transport and simulations in a rectangular harbor

    International Nuclear Information System (INIS)

    Matsuyama, Masafumi

    2009-01-01

    Characteristics of formulae for bed-load transport and pick-up rate in suspended transport are investigated in order to clarify the impact on seabed topography changes by tsunami flow. The impact by bed-load transport was depended on Froude number and water surface slope. Bed-load transport causes deposition under Fr 6/7 at face front of tsunami wave. Pick-up rate has more predominant influences for seabed topography changes than that of one brought by bed-load transport. 2-D Numerical simulations with formulae by Ikeno et.al were carried out to simulate topography changes around harbor by tsunami flow in the flume. The result indicated that the numerical model is more applicable than a numerical model with previous formulae for estimation of deposit and erosion by topography changes. It is for this reason that the formula of pick-up rate is adaptable for wide-range diameter of sand, from 0.08mm to 0.2mm. Upper limit of suspended sediment concentration is needed to set due to avoid overlarge concentration in the numerical model. Comparison between numerical results in a real scale with 1% and 5% upper limits clearly shows topography changes have a deep relevance with the upper limit value. The upper limit value is one of dominant factors for evaluating seabed topography changes by the 2-D Numerical simulations with the formulae by Ikeno et.al in a real scale. (author)

  6. Pearl Harbor Biological Survey

    Science.gov (United States)

    1974-08-30

    Pearl Harbor also receives Irrigation tailgate waters from the Oahu Sug- ar Company, Industrial waste waters from the Prlmo Brewery , and heated waters...34Observations of the Cell Structure of Salt Fingers", J. Fluid Mech. 41:4, pp 707-719. ~) 3.3-79 ,’:•.-. ^ IV s’V- EFFECTS OF SHIP ACTIVITY Paul L...anticyclonic) death assemblage - in this report, an assemblage (q.v.) of remains (such as shells or bones ) from a naturally occurring association of living

  7. Model of the transverse modes of stable and unstable porro–prism resonators using symmetry considerations

    CSIR Research Space (South Africa)

    Burger, L

    2007-01-01

    Full Text Available of this type of resonator. Further use of the model reveals the formation of more complex beam patterns, and the nature of these patterns is investigated. Also, the output of stable and unstable resonator modes is presented....

  8. Modelling of optoelectronic circuits based on resonant tunneling diodes

    Science.gov (United States)

    Rei, João. F. M.; Foot, James A.; Rodrigues, Gil C.; Figueiredo, José M. L.

    2017-08-01

    Resonant tunneling diodes (RTDs) are the fastest pure electronic semiconductor devices at room temperature. When integrated with optoelectronic devices they can give rise to new devices with novel functionalities due to their highly nonlinear properties and electrical gain, with potential applications in future ultra-wide-band communication systems (see e.g. EU H2020 iBROW Project). The recent coverage on these devices led to the need to have appropriated simulation tools. In this work, we present RTD based optoelectronic circuits simulation packages to provide circuit signal level analysis such as transient and frequency responses. We will present and discuss the models, and evaluate the simulation packages.

  9. Covariant introduction of quark spin into the dual resonance model

    International Nuclear Information System (INIS)

    Iroshnikov, G.S.

    1979-01-01

    A very simple method of insertion of a quark spin into the dual resonance model of hadron interaction is proposed. The method is suitable for amplitudes with an arbitrary number of particles. The amplitude of interaction of real particles is presented as a product of contribution of oscillatory excitations in the (q anti q) system and of a spin factor. The latter is equal to the trace of the product of the external particle wave functions constructed from structural quarks and satisfying the relativistic Bargman-Wigner equations. Two examples of calculating the meson interaction amplitudes are presented

  10. Parton recombination model including resonance production. RL-78-040

    International Nuclear Information System (INIS)

    Roberts, R.G.; Hwa, R.C.; Matsuda, S.

    1978-05-01

    Possible effects of resonance production on the meson inclusive distribution in the fragmentation region are investigated in the framework of the parton recombination model. From a detailed study of the data on vector-meson production, a reliable ratio of the vector-to-pseudoscalar rates is determined. Then the influence of the decay of the vector mesons on the pseudoscalar spectrum is examined, and the effect found to be no more than 25% for x > 0.5. The normalization of the non-strange antiquark distributions are still higher than those in a quiescent proton. The agreement between the calculated results and data remain very good. 36 references

  11. Modelling of Resonantly Forced Density Waves in Dense Planetary Rings

    Science.gov (United States)

    Lehmann, M.; Schmidt, J.; Salo, H.

    2014-04-01

    Density wave theory, originally proposed to explain the spiral structure of galactic disks, has been applied to explain parts of the complex sub-structure in Saturn's rings, such as the wavetrains excited at the inner Lindblad resonances (ILR) of various satellites. The linear theory for the excitation and damping of density waves in Saturn's rings is fairly well developed (e.g. Goldreich & Tremaine [1979]; Shu [1984]). However, it fails to describe certain aspects of the observed waves. The non-applicability of the linear theory is already indicated by the "cusplike" shape of many of the observed wave profiles. This is a typical nonlinear feature which is also present in overstability wavetrains (Schmidt & Salo [2003]; Latter & Ogilvie [2010]). In particular, it turns out that the detailed damping mechanism, as well as the role of different nonlinear effects on the propagation of density waves remain intransparent. First attemps are being made to investigate the excitation and propagation of nonlinear density waves within a hydrodynamical formalism, which is also the natural formalism for describing linear density waves. A simple weakly nonlinear model, derived from a multiple-scale expansion of the hydrodynamic equations, is presented. This model describes the damping of "free" spiral density waves in a vertically integrated fluid disk with density dependent transport coefficients, where the effects of the hydrodynamic nonlinearities are included. The model predicts that density waves are linearly unstable in a ring region where the conditions for viscous overstability are met, which translates to a steep dependence of the shear viscosity with respect to the disk's surface density. The possibility that this dependence could lead to a growth of density waves with increasing distance from the resonance, was already mentioned in Goldreich & Tremaine [1978]. Sufficiently far away from the ILR, the surface density perturbation caused by the wave, is predicted to

  12. Parton recombination model including resonance production. RL-78-040

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, R. G.; Hwa, R. C.; Matsuda, S.

    1978-05-01

    Possible effects of resonance production on the meson inclusive distribution in the fragmentation region are investigated in the framework of the parton recombination model. From a detailed study of the data on vector-meson production, a reliable ratio of the vector-to-pseudoscalar rates is determined. Then the influence of the decay of the vector mesons on the pseudoscalar spectrum is examined, and the effect found to be no more than 25% for x > 0.5. The normalization of the non-strange antiquark distributions are still higher than those in a quiescent proton. The agreement between the calculated results and data remain very good. 36 references.

  13. Stochastic resonance in a generalized Von Foerster population growth model

    Energy Technology Data Exchange (ETDEWEB)

    Lumi, N.; Mankin, R. [Institute of Mathematics and Natural Sciences, Tallinn University, 25 Narva Road, 10120 Tallinn (Estonia)

    2014-11-12

    The stochastic dynamics of a population growth model, similar to the Von Foerster model for human population, is studied. The influence of fluctuating environment on the carrying capacity is modeled as a multiplicative dichotomous noise. It is established that an interplay between nonlinearity and environmental fluctuations can cause single unidirectional discontinuous transitions of the mean population size versus the noise amplitude, i.e., an increase of noise amplitude can induce a jump from a state with a moderate number of individuals to that with a very large number, while by decreasing the noise amplitude an opposite transition cannot be effected. An analytical expression of the mean escape time for such transitions is found. Particularly, it is shown that the mean transition time exhibits a strong minimum at intermediate values of noise correlation time, i.e., the phenomenon of stochastic resonance occurs. Applications of the results in ecology are also discussed.

  14. Interacting hadron resonance gas model in the K -matrix formalism

    Science.gov (United States)

    Dash, Ashutosh; Samanta, Subhasis; Mohanty, Bedangadas

    2018-05-01

    An extension of hadron resonance gas (HRG) model is constructed to include interactions using relativistic virial expansion of partition function. The noninteracting part of the expansion contains all the stable baryons and mesons and the interacting part contains all the higher mass resonances which decay into two stable hadrons. The virial coefficients are related to the phase shifts which are calculated using K -matrix formalism in the present work. We have calculated various thermodynamics quantities like pressure, energy density, and entropy density of the system. A comparison of thermodynamic quantities with noninteracting HRG model, calculated using the same number of hadrons, shows that the results of the above formalism are larger. A good agreement between equation of state calculated in K -matrix formalism and lattice QCD simulations is observed. Specifically, the lattice QCD calculated interaction measure is well described in our formalism. We have also calculated second-order fluctuations and correlations of conserved charges in K -matrix formalism. We observe a good agreement of second-order fluctuations and baryon-strangeness correlation with lattice data below the crossover temperature.

  15. PTM Modeling of Dredged Suspended Sediment at Proposed Polaris Point and Ship Repair Facility CVN Berthing Sites - Apra Harbor, Guam

    Science.gov (United States)

    2017-09-01

    sedimentation outside of the channel footprint. For example, dredging near the edge of the footprint can be confined to time periods when tidal currents...Cases 1 or 2 due to the lower loss rate. Sedimentation rates outside the channel prism are further reduced because all sediment is introduced in the...ER D C/ CH L TR -1 7- 16 PTM Modeling of Dredged Suspended Sediment at Proposed Polaris Point and Ship Repair Facility CVN Berthing

  16. Grays Harbor Paper

    Energy Technology Data Exchange (ETDEWEB)

    Quigg, B. [Grays Harbor Paper, Hoquiam, WA (United States)

    2009-07-01

    Wood waste biomass boilers are used at Grays Harbor Paper in Hoquiam, Washington. This presentation showed that large volumes of biomass are left after a traditional clearcut. The opportunities and challenges of collecting branches, tops and stumps from this wet coastal climate were outlined. The paper described some of the low-tech methods for picking up branches, stumps and woody debris. It included several photographs of custom logging machines for timber harvest, including a brush grapple slasher, a shearer shovel, chippers, grinders, slicesaws, trucks, trailers and caterpillar log loaders for handling slash. The slash recovery program relies on innovative harvesting machines that convert scattered logging slash into bundles that can be easily collected, transported, and stored for use in existing facilities that utilize wood fiber for fuel. figs.

  17. RESONANCE

    Indian Academy of Sciences (India)

    To the extent that genes influence our behaviour it may well be that our ... other by a coefficient of genetic relatedness r of 0.75 but a female. Figure 1. ... cal and empirical work. ... rather famous one is called PSR, for paternally transmitted sex ... Life cycle of ... Genic balance sex determination (GBSD): According to this model ...

  18. Modeling for the SAFRR Tsunami Scenario-generation, propagation, inundation, and currents in ports and harbors: Chapter D in The SAFRR (Science Application for Risk Reduction) Tsunami Scenario

    Science.gov (United States)

    ,

    2013-01-01

    This U.S. Geological Survey (USGS) Open-File report presents a compilation of tsunami modeling studies for the Science Application for Risk Reduction (SAFRR) tsunami scenario. These modeling studies are based on an earthquake source specified by the SAFRR tsunami source working group (Kirby and others, 2013). The modeling studies in this report are organized into three groups. The first group relates to tsunami generation. The effects that source discretization and horizontal displacement have on tsunami initial conditions are examined in section 1 (Whitmore and others). In section 2 (Ryan and others), dynamic earthquake rupture models are explored in modeling tsunami generation. These models calculate slip distribution and vertical displacement of the seafloor as a result of realistic fault friction, physical properties of rocks surrounding the fault, and dynamic stresses resolved on the fault. The second group of papers relates to tsunami propagation and inundation modeling. Section 3 (Thio) presents a modeling study for the entire California coast that includes runup and inundation modeling where there is significant exposure and estimates of maximum velocity and momentum flux at the shoreline. In section 4 (Borrero and others), modeling of tsunami propagation and high-resolution inundation of critical locations in southern California is performed using the National Oceanic and Atmospheric Administration’s (NOAA) Method of Splitting Tsunami (MOST) model and NOAA’s Community Model Interface for Tsunamis (ComMIT) modeling tool. Adjustments to the inundation line owing to fine-scale structures such as levees are described in section 5 (Wilson). The third group of papers relates to modeling of hydrodynamics in ports and harbors. Section 6 (Nicolsky and Suleimani) presents results of the model used at the Alaska Earthquake Information Center for the Ports of Los Angeles and Long Beach, as well as synthetic time series of the modeled tsunami for other selected

  19. Interacting-string picture of dual-resonance models

    International Nuclear Information System (INIS)

    Mandelstam, S.

    1985-01-01

    Dual-resonance models are an alyzed by means of operators which act within the physical Hilbert space of positive-metric states. The basis of the method is to extend the relativistic-string picture of a previous study to interacting particles. Functional methods are used, but their relation to the operator is evident, and factorization is maintained. An expression is given for the N-point amplitude in terms of physical-particle operators. For the three-point function the Neumann functions which occur in this expression are evaluated, so that we have a formula for the on- and off-energy-shell vertex. The authors assume that the string has no longitudinal degrees of freedom, and their results are Lorentz invariant and dual only if d=26

  20. The inherent complexity in nonlinear business cycle model in resonance

    International Nuclear Information System (INIS)

    Ma Junhai; Sun Tao; Liu Lixia

    2008-01-01

    Based on Abraham C.-L. Chian's research, we applied nonlinear dynamic system theory to study the first-order and second-order approximate solutions to one category of the nonlinear business cycle model in resonance condition. We have also analyzed the relation between amplitude and phase of second-order approximate solutions as well as the relation between outer excitements' amplitude, frequency approximate solutions, and system bifurcation parameters. Then we studied the system quasi-periodical solutions, annulus periodical solutions and the path leading to system bifurcation and chaotic state with different parameter combinations. Finally, we conducted some numerical simulations for various complicated circumstances. Therefore this research will lay solid foundation for detecting the complexity of business cycles and systems in the future

  1. Polyakov loop and the hadron resonance gas model.

    Science.gov (United States)

    Megías, E; Arriola, E Ruiz; Salcedo, L L

    2012-10-12

    The Polyakov loop has been used repeatedly as an order parameter in the deconfinement phase transition in QCD. We argue that, in the confined phase, its expectation value can be represented in terms of hadronic states, similarly to the hadron resonance gas model for the pressure. Specifically, L(T)≈1/2[∑(α)g(α)e(-Δ(α)/T), where g(α) are the degeneracies and Δ(α) are the masses of hadrons with exactly one heavy quark (the mass of the heavy quark itself being subtracted). We show that this approximate sum rule gives a fair description of available lattice data with N(f)=2+1 for temperatures in the range 150 MeVmodels. For temperatures below 150 MeV different lattice results disagree. One set of data can be described if exotic hadrons are present in the QCD spectrum while other sets do not require such states.

  2. Numerical model of electron cyclotron resonance ion source

    Directory of Open Access Journals (Sweden)

    V. Mironov

    2015-12-01

    Full Text Available Important features of the electron cyclotron resonance ion source (ECRIS operation are accurately reproduced with a numerical code. The code uses the particle-in-cell technique to model the dynamics of ions in ECRIS plasma. It is shown that a gas dynamical ion confinement mechanism is sufficient to provide the ion production rates in ECRIS close to the experimentally observed values. Extracted ion currents are calculated and compared to the experiment for a few sources. Changes in the simulated extracted ion currents are obtained with varying the gas flow into the source chamber and the microwave power. Empirical scaling laws for ECRIS design are studied and the underlying physical effects are discussed.

  3. Gridded multibeam bathymetry of Apra Harbor, Guam U.S. Territory

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Gridded bathymetry from Apra Harbor, Guam U.S. Territory. The netCDF and Arc ASCII grids include multibeam bathymetry from the Reson SeaBat 8125 multibeam sonar...

  4. Matter-neutrino resonance in a multiangle neutrino bulb model

    Science.gov (United States)

    Vlasenko, Alexey; McLaughlin, G. C.

    2018-04-01

    Simulations of neutrino flavor evolution in compact merger environments have shown that neutrino flavor, and hence nucleosynthesis, can be strongly affected by the presence of matter-neutrino resonances (MNRs), where there is a cancelation between the matter and the neutrino potential. Simulations performed thus far follow flavor evolution along a single neutrino trajectory, but self-consistency requires all trajectories to be treated simultaneously, and it has not been known whether MNR phenomena would still occur in multiangle models. In this paper, we present the first fully multi-angle calculations of MNR. We find that familiar MNR phenomena, where neutrinos transform to a greater extent than anti-neutrinos and a feedback mechanism maintains the cancellation between the matter and neutrino potential, still occurs for a subset of angular bins, although the flavor transformation is not as efficient as in the single-angle case. In addition, we find other types of flavor transformation that are not seen in single-angle simulations. These flavor transformation phenomena appear to be robust and are present for a wide range of model parameters, as long as an MNR is present. Although computational constraints currently limit us to models with spherical symmetry, our results suggest that the presence of an MNR generally leads to large-scale neutrino flavor evolution in multiangle systems.

  5. Application of Resonant Converter in Ozone Generator Model

    Directory of Open Access Journals (Sweden)

    Mochammad Facta

    2008-04-01

    Full Text Available Ozone is one of the favorable oxidant to use in home appliance and industry as disinfectant for food processing, food storage, odor abatement, groundwater remediation, and drinking water purification. The common and previous technical method for generating ozone uses a high voltage and low frequency. This kind of method has disadvantage of energy efficiency, size and weight. This paper proposed the use power electronics in the inverter resonant circuit to produce alternating current with high frequency. The basic RLC resonance circuit is used for early study to determine resonance frequency for inverter. As the result, the ozone chamber terminal voltage had been achieved for initiation by using resonance frequency.

  6. Modelling and analysis of the transformer current resonance in dual active bridge converters

    DEFF Research Database (Denmark)

    Qin, Zian; Shen, Zhan; Blaabjerg, Frede

    2017-01-01

    Due to the parasitic capacitances of the transformer and inductor in Dual Active Bridge (DAB) converters, resonance happens in the transformer currents. This high frequency resonant current flowing into the full bridges will worsen their soft-switching performance and thereby reduce its efficiency....... In order to study the generation mechanism of this current resonance, the impedance of the transformer and inductor with parasitic components is modelled in this digest. Then, based on the impedance model, an approach is proposed to mitigate the current resonance. Finally, both the impedance model...

  7. Doorway-resonance model for pion-nucleon D- and F-wave scattering

    International Nuclear Information System (INIS)

    Ernst, D.J.; Parnell, G.E.; Assad, C.; Texas A and M Univ., College Station, TX

    1990-01-01

    A model for the resonant pion-nucleon D- and F-waves is developed which assumes that the pion-plus-nucleon couples to a resonance and that the resonance can serve as a doorway to the inelastic channels. With the use of simple form factors, the model is capable of reproducing the pion-nucleon phase shifts up to an energy of T π =1.4 GeV if the coupling of the elastic channel to the inelastic channels is taken from data as input into the model. A value for the mass of the resonance that would result in the absence of the coupling to decay channels is extracted from the data utilizing the model. This is the mass that is most easily modeled by bag models. For the non-resonant D- and F-wave channels a separable potential model is used. This model, like the resonance model, is developed utilizing the invariant amplitude which is free of kinematic singularities and uses invariant norms and phase spaces. The model is also applied to the S-wave channels. A relation between the resonance model and the Chew-Low model is discovered and used to derive an extended Chew-Low model which is applied to the P 13 , P 31 and P 33 channels. Implications of the model for understanding the range of the pion-nucleon interaction and the dynamic structure of the interaction are presented. (orig.)

  8. A three-dimensional model for calculating the micro disk laser resonant-modes

    International Nuclear Information System (INIS)

    Sabetjoo, H.; Bahrampor, A.; Farrahi-Moghaddam, R.

    2006-01-01

    In this article, a semi-analytical model for theoretical analysis of micro disk lasers is presented. Using this model, the necessary conditions for the existence of loss less and low-loss modes of micro-resonators are obtained. The resonance frequency of the resonant modes and also the attenuation of low-loss modes are calculated. By comparing the results with results of finite difference method, their validity is certified.

  9. Self-consistent modeling of electron cyclotron resonance ion sources

    International Nuclear Information System (INIS)

    Girard, A.; Hitz, D.; Melin, G.; Serebrennikov, K.; Lecot, C.

    2004-01-01

    In order to predict the performances of electron cyclotron resonance ion source (ECRIS), it is necessary to perfectly model the different parts of these sources: (i) magnetic configuration; (ii) plasma characteristics; (iii) extraction system. The magnetic configuration is easily calculated via commercial codes; different codes also simulate the ion extraction, either in two dimension, or even in three dimension (to take into account the shape of the plasma at the extraction influenced by the hexapole). However the characteristics of the plasma are not always mastered. This article describes the self-consistent modeling of ECRIS: we have developed a code which takes into account the most important construction parameters: the size of the plasma (length, diameter), the mirror ratio and axial magnetic profile, whether a biased probe is installed or not. These input parameters are used to feed a self-consistent code, which calculates the characteristics of the plasma: electron density and energy, charge state distribution, plasma potential. The code is briefly described, and some of its most interesting results are presented. Comparisons are made between the calculations and the results obtained experimentally

  10. Self-consistent modeling of electron cyclotron resonance ion sources

    Science.gov (United States)

    Girard, A.; Hitz, D.; Melin, G.; Serebrennikov, K.; Lécot, C.

    2004-05-01

    In order to predict the performances of electron cyclotron resonance ion source (ECRIS), it is necessary to perfectly model the different parts of these sources: (i) magnetic configuration; (ii) plasma characteristics; (iii) extraction system. The magnetic configuration is easily calculated via commercial codes; different codes also simulate the ion extraction, either in two dimension, or even in three dimension (to take into account the shape of the plasma at the extraction influenced by the hexapole). However the characteristics of the plasma are not always mastered. This article describes the self-consistent modeling of ECRIS: we have developed a code which takes into account the most important construction parameters: the size of the plasma (length, diameter), the mirror ratio and axial magnetic profile, whether a biased probe is installed or not. These input parameters are used to feed a self-consistent code, which calculates the characteristics of the plasma: electron density and energy, charge state distribution, plasma potential. The code is briefly described, and some of its most interesting results are presented. Comparisons are made between the calculations and the results obtained experimentally.

  11. Systematic assignment of Feshbach resonances via an asymptotic bound state model

    NARCIS (Netherlands)

    Goosen, M.; Kokkelmans, SJ.J.M.F.

    2008-01-01

    We present an Asymptotic Bound state Model (ABM), which is useful to predict Feshbach resonances. The model utilizes asymptotic properties of the interaction potentials to represent coupled molecular wavefunctions. The bound states of this system give rise to Feshbach resonances, localized at the

  12. Analytical model for double split ring resonators with arbitrary ring width

    DEFF Research Database (Denmark)

    Zhurbenko, Vitaliy; Jensen, Thomas; Krozer, Viktor

    2008-01-01

    For the first time, the analytical model for a double split ring resonator with unequal width rings is developed. The proposed models for the resonators with equal and unequal widths are based on an impedance matrix representation and provide the prediction of performance in a wide frequency range...

  13. Alaska Harbor Seal Glacial Surveys

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Floating glacial ice serves as a haul-out substrate for a significant number (10-15%) of Alaskan harbor seals, and thus surveying tidewater glacial fjords is an...

  14. Detection and quantification of creep strain using process compensated resonance testing (PCRT) sorting modules trained with modeled resonance spectra

    Science.gov (United States)

    Heffernan, Julieanne; Biedermann, Eric; Mayes, Alexander; Livings, Richard; Jauriqui, Leanne; Goodlet, Brent; Aldrin, John C.; Mazdiyasni, Siamack

    2018-04-01

    Process Compensated Resonant Testing (PCRT) is a full-body nondestructive testing (NDT) method that measures the resonance frequencies of a part and correlates them to the part's material and/or damage state. PCRT testing is used in the automotive, aerospace, and power generation industries via automated PASS/FAIL inspections to distinguish parts with nominal process variation from those with the defect(s) of interest. Traditional PCRT tests are created through the statistical analysis of populations of "good" and "bad" parts. However, gathering a statistically significant number of parts can be costly and time-consuming, and the availability of defective parts may be limited. This work uses virtual databases of good and bad parts to create two targeted PCRT inspections for single crystal (SX) nickel-based superalloy turbine blades. Using finite element (FE) models, populations were modeled to include variations in geometric dimensions, material properties, crystallographic orientation, and creep damage. Model results were verified by comparing the frequency variation in the modeled populations with the measured frequency variations of several physical blade populations. Additionally, creep modeling results were verified through the experimental evaluation of coupon geometries. A virtual database of resonance spectra was created from the model data. The virtual database was used to create PCRT inspections to detect crystallographic defects and creep strain. Quantification of creep strain values using the PCRT inspection results was also demonstrated.

  15. A one-dimensional model of resonances with a delta barrier and mass jump

    International Nuclear Information System (INIS)

    Alvarez, J.J.; Gadella, M.; Heras, F.J.H.; Nieto, L.M.

    2009-01-01

    In this Letter, we present a one-dimensional model that includes a hard core at the origin, a Dirac delta barrier at a point in the positive semiaxis and a mass jump at the same point. We study the effect of this mass jump in the behavior of the resonances of the model. We obtain an infinite number of resonances for this situation, showing that for the case of a mass jump the imaginary part of the resonance poles tend to a fixed value depending on the quotient of masses, and demonstrate that none of these resonances is degenerated.

  16. Magnetic resonance spectroscopy of traumatic brain in SD rats model

    International Nuclear Information System (INIS)

    Li Ke; Li Yangbin; Li Zhiming; Huang Yong; Li Bin; Lu Guangming

    2009-01-01

    Objective: To assess the value and prospect of magnetic resonance spectroscopy (MRS) in early diagnosis of traumatic brain with traumatic brain model in SD rats. Methods: Traumatic brain modal was established in 40 male SD rats utilizing a weigh-drop device, and MRS was performed before trauma and 4,8,24 and 48 hours after trauma. The ratio of N-acetylaspartate/creatine (NAA/Ct) and choline/creatine (Cho/Cr) were calculated and compared with pathological findings respectively. Results: Axonal changes were confirmed in microscopic study 4 hours after injury. The ratio of NAA/Ct decreased distinctly at 4 hours after trauma, followed by a steadily recover at 8 hours, and no significant change from 24h to 48h. There was no significant change in the ratio of Cho/Cr before and after trauma. Conclusion: MRS can be used to monitor the metabolic changes of brain non-invasively. MRS could play a positive role in early diagnosis, prognosis and follow-up of traumatic brain. (authors)

  17. Model for decays of boson resonances with arbitrary spins

    International Nuclear Information System (INIS)

    Grigoryan, A.A.; Ivanov, N.Ya.

    1985-01-01

    A formula for the width of resonance with spin J decay into hadrons with arbitrary spins is derived. This width is expressed via S-channel helicity residues of Regge trajectory α J where the resonance J lies. Using the quark-gluon picture predictions for the coupling of quarks with Regge trajectories and SU(6)-classification of hadrons this formula is applied to calculate the widths of decays of resonances, which lie on the vector and tensor trajectories, into pseudoscalar and vector, two vectors and NN-bar-pair

  18. Analysis and Modeling of Integrated Magnetics for LLC resonant Converters

    DEFF Research Database (Denmark)

    Li, Mingxiao; Ouyang, Ziwei; Zhao, Bin

    2017-01-01

    Shunt-inserted transformers are widely used toobtain high leakage inductance. This paper investigates thismethod in depth to make it applicable to integrate resonantinductor for the LLC resonant converters. The analysis andmodel of magnetizing inductance and leakage inductance forshunt...... transformers can provide a significantdifference. The way to obtain the desirable magnetizing andleakage inductance value for LLC resonant converters issimplified by the creation of air gaps together with a magneticshunt. The calculation and relation are validated by finiteelement analysis (FEA) simulations...

  19. Two-Mode Resonator and Contact Model for Standing Wave Piezomotor

    DEFF Research Database (Denmark)

    Andersen, B.; Blanke, Mogens; Helbo, J.

    2001-01-01

    The paper presents a model for a standing wave piezoelectric motor with a two bending mode resonator. The resonator is modelled using Hamilton's principle and the Rayleigh-Ritz method. The contact is modelled using the Lagrange Multiplier method under the assumption of slip and it is showed how...... to solve the set of differential-algebraic equations. Detailed simulations show resonance frequencies as function of the piezoelement's position, tip trajectories and contact forces. The paper demonstrates that contact stiffness and stick should be included in such model to obtain physically realistic...

  20. Environmental Light and Its Relationship with Electromagnetic Resonances of Biomolecular Interactions, as Predicted by the Resonant Recognition Model

    Directory of Open Access Journals (Sweden)

    Irena Cosic

    2016-06-01

    Full Text Available The meaning and influence of light to biomolecular interactions, and consequently to health, has been analyzed using the Resonant Recognition Model (RRM. The RRM proposes that biological processes/interactions are based on electromagnetic resonances between interacting biomolecules at specific electromagnetic frequencies within the infra-red, visible and ultra-violet frequency ranges, where each interaction can be identified by the certain frequency critical for resonant activation of specific biological activities of proteins and DNA. We found that: (1 the various biological interactions could be grouped according to their resonant frequency into super families of these functions, enabling simpler analyses of these interactions and consequently analyses of influence of electromagnetic frequencies to health; (2 the RRM spectrum of all analyzed biological functions/interactions is the same as the spectrum of the sun light on the Earth, which is in accordance with fact that life is sustained by the sun light; (3 the water is transparent to RRM frequencies, enabling proteins and DNA to interact without loss of energy; (4 the spectrum of some artificial sources of light, as opposed to the sun light, do not cover the whole RRM spectrum, causing concerns for disturbance to some biological functions and consequently we speculate that it can influence health.

  1. A statistical model for combustion resonance from a DI diesel engine with applications

    Science.gov (United States)

    Bodisco, Timothy; Low Choy, Samantha; Masri, Assaad; Brown, Richard J.

    2015-08-01

    Introduced in this paper is a Bayesian model for isolating the resonant frequency from combustion chamber resonance. The model shown in this paper focused on characterising the initial rise in the resonant frequency to investigate the rise of in-cylinder bulk temperature associated with combustion. By resolving the model parameters, it is possible to determine: the start of pre-mixed combustion, the start of diffusion combustion, the initial resonant frequency, the resonant frequency as a function of crank angle, the in-cylinder bulk temperature as a function of crank angle and the trapped mass as a function of crank angle. The Bayesian method allows for individual cycles to be examined without cycle-averaging-allowing inter-cycle variability studies. Results are shown for a turbo-charged, common-rail compression ignition engine run at 2000 rpm and full load.

  2. Numerical analysis of the resonance mechanism of the lumped parameter system model for acoustic mine detection

    International Nuclear Information System (INIS)

    Wang Chi; Zhou Yu-Qiu; Shen Gao-Wei; Wu Wen-Wen; Ding Wei

    2013-01-01

    The method of numerical analysis is employed to study the resonance mechanism of the lumped parameter system model for acoustic mine detection. Based on the basic principle of the acoustic resonance technique for mine detection and the characteristics of low-frequency acoustics, the ''soil-mine'' system could be equivalent to a damping ''mass-spring'' resonance model with a lumped parameter analysis method. The dynamic simulation software, Adams, is adopted to analyze the lumped parameter system model numerically. The simulated resonance frequency and anti-resonance frequency are 151 Hz and 512 Hz respectively, basically in agreement with the published resonance frequency of 155 Hz and anti-resonance frequency of 513 Hz, which were measured in the experiment. Therefore, the technique of numerical simulation is validated to have the potential for analyzing the acoustic mine detection model quantitatively. The influences of the soil and mine parameters on the resonance characteristics of the soil—mine system could be investigated by changing the parameter setup in a flexible manner. (electromagnetism, optics, acoustics, heat transfer, classical mechanics, and fluid dynamics)

  3. The computer simulation of the resonant network for the B-factory model power supply

    International Nuclear Information System (INIS)

    Zhou, W.; Endo, K.

    1993-07-01

    A high repetition model power supply and the resonant magnet network are simulated with the computer in order to check and improve the design of the power supply for the B-factory booster. We put our key point on a transient behavior of the power supply and the resonant magnet network. The results of the simulation are given. (author)

  4. Case study of small harbor excitation under storm and tsunami conditions

    Science.gov (United States)

    Synolakis, Costas; Maravelakis, Nikos; Kalligeris, Nikos; Skanavis, Vassilios; Kanoglu, Utku; Yalciner, Ahmet; Lynett, Pat

    2016-04-01

    Simultaneous nearshore and interior-to-ports wave and current measurements for small ports are not common, and few, if any, benchmarking cases at sufficient resolution exist to help validate numerical model of intermediate waves, or even long waves. The wave conditions inside the old Venetian harbor of Chania, Greece and offshore were measured and studied from 2012 to 2015. The construction of this harbor began in the 14th century, and since then, its layout has been modified to adapt to different social and to economic conditions. It is divided into a western and an eastern basin. The eastern basin is used by recreational vessels and fishing boats throughout the year. The western basin has an exposed entrance to the north, and it is essentially functional half of the year, because of the severe overtopping and flooding that occur during the northern winter storms. Our work is motivated by the necessity to protect the monument from severe winter storm conditions and allow safe mooring and all other recreational activities that take place in the exposed western basin. Two earlier studies had proposed the construction of a low crested breakwater near the harbor entrance. The first design has been partially constructed, while the second never materialized. The main disadvantage of both studies was the lack of any wave field measurements. At the same time, second order or complimentary phenomena such as harbor resonance had not been considered. To address the lack of field data, the offshore wave climate has been monitored since October 2012 using an AWAC 600kHz instrument, deployed at 23m depth. The response of the western and eastern basins of the harbor was measured with a TWR-2050 (deployed at 5.5m depth) and an RBRDuet T.D./wave (deployed at 2m depth) pressure gauges respectively. Significant wave heights ranging up to 5.8 m with significant periods of up to 10 sec were measured. The harbor pressure gauges are now being re-deployed in other locations to collect

  5. Using Micromechanical Resonators to Measure Rheological Properties and Alcohol Content of Model Solutions and Commercial Beverages

    Directory of Open Access Journals (Sweden)

    Bart W. Hoogenboom

    2012-05-01

    Full Text Available Micromechanic resonators provide a small-volume and potentially high-throughput method to determine rheological properties of fluids. Here we explore the accuracy in measuring mass density and viscosity of ethanol-water and glycerol-water model solutions, using a simple and easily implemented model to deduce the hydrodynamic effects on resonating cantilevers of various length-to-width aspect ratios. We next show that these measurements can be extended to determine the alcohol percentage of both model solutions and commercial beverages such as beer, wine and liquor. This demonstrates how micromechanical resonators can be used for quality control of every-day drinks.

  6. Geoscience rediscovers Phoenicia's buried harbors

    Science.gov (United States)

    Marriner, Nick; Morhange, Christophe; Doumet-Serhal, Claude; Carbonel, Pierre

    2006-01-01

    After centuries of archaeological debate, the harbors of Phoenicia's two most important city states, Tyre and Sidon, have been rediscovered, and including new geoarcheological results reveal how, where, and when they evolved after their Bronze Age foundations. The early ports lie beneath their present urban centers, and we have indentified four harbor phases. (1) During the Bronze Age, Tyre and Sidon were characterized by semi-open marine coves that served as protoharbors. (2) Biostratigraphic and lithostratigraphic data indicate the presence of early artificial basins after the first millennium B.C. (3) The harbors reached their apogees during the Greco-Roman and Byzantine periods. (4) Silting up and coastal progradation led to burial of the medieval basins, lost until now.

  7. dutch_harbor.grd

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NGDC builds and distributes high-resolution, coastal digital elevation models (DEMs) that integrate ocean bathymetry and land topography to support NOAA's mission to...

  8. Mathematical model of thyristor inverter including a series-parallel resonant circuit

    OpenAIRE

    Luft, M.; Szychta, E.

    2008-01-01

    The article presents a mathematical model of thyristor inverter including a series-parallel resonant circuit with the aid of state variable method. Maple procedures are used to compute current and voltage waveforms in the inverter.

  9. Mathematical Model of Thyristor Inverter Including a Series-parallel Resonant Circuit

    OpenAIRE

    Miroslaw Luft; Elzbieta Szychta

    2008-01-01

    The article presents a mathematical model of thyristor inverter including a series-parallel resonant circuit with theaid of state variable method. Maple procedures are used to compute current and voltage waveforms in the inverter.

  10. Mathematical Model of Thyristor Inverter Including a Series-parallel Resonant Circuit

    Directory of Open Access Journals (Sweden)

    Miroslaw Luft

    2008-01-01

    Full Text Available The article presents a mathematical model of thyristor inverter including a series-parallel resonant circuit with theaid of state variable method. Maple procedures are used to compute current and voltage waveforms in the inverter.

  11. Compact extended model for doppler broadening of neutron absorption resonances in solids

    International Nuclear Information System (INIS)

    Villanueva, A. J; Granada, J.R

    2009-01-01

    We present a simplified compact model for calculating Doppler broadening of neutron absorption resonances in an incoherent Debye solid. Our model extends the effective temperature gas model to cover the whole range of energies and temperatures, and reduces the information of the dynamical system to a minimum content compatible with a much better accuracy of the calculation. This model is thus capable of replacing the existing algorithm in standard codes for resonance cross sections preparation aimed at neutron and reactor physics calculations. The model is applied to the 238 U 6.671 eV effective broadened cross section. We also show how this model can be used for thermometry in an improved fashion compared to the effective temperature gas model. Experimental data of the same resonance at low and high temperatures are also shown and the performances of each model are put to the test on this basis. [es

  12. Neutron strength functions: the link between resolved resonances and the optical model

    International Nuclear Information System (INIS)

    Moldauer, P.A.

    1980-01-01

    Neutron strength functions and scattering radii are useful as energy and channel radius independent parameters that characterize neutron scattering resonances and provide a connection between R-matrix resonance analysis and the optical model. The choice of R-matrix channel radii is discussed, as are limitations on the accuracies of strength functions. New definitions of the p-wave strength function and scattering radius are proposed. For light nuclei, where strength functions display optical model energy variations over the resolved resonances, a doubly reduced partial neutron width is introduced for more meaningful statistical analyses of widths. The systematic behavior of strength functions and scattering radii is discussed

  13. Correlations between resonances in a statistical scattering model

    International Nuclear Information System (INIS)

    Gorin, T.; Rotter, I.

    1997-01-01

    The distortion of the regular motion in a quantum system by its coupling to the continuum of decay channels is investigated. The regular motion is described by means of a Poissonian ensemble. We focus on the case of only few channels K 2 K distribution in the GOE case. 2. Due to the coupling to the continuum, correlations are induced not only between the positions of the resonances but also between positions and widths. These correlations remain even in the strong coupling limit. In order to explain these results, an asymptotic expression for the width distribution is derived for the one channel case. It relates the width of a trapped resonance state to the distance between its two neighboring levels. (orig.)

  14. Self-consistent modelling of resonant tunnelling structures

    DEFF Research Database (Denmark)

    Fiig, T.; Jauho, A.P.

    1992-01-01

    We report a comprehensive study of the effects of self-consistency on the I-V-characteristics of resonant tunnelling structures. The calculational method is based on a simultaneous solution of the effective-mass Schrödinger equation and the Poisson equation, and the current is evaluated...... applied voltages and carrier densities at the emitter-barrier interface. We include the two-dimensional accumulation layer charge and the quantum well charge in our self-consistent scheme. We discuss the evaluation of the current contribution originating from the two-dimensional accumulation layer charges......, and our qualitative estimates seem consistent with recent experimental studies. The intrinsic bistability of resonant tunnelling diodes is analyzed within several different approximation schemes....

  15. Resonance phenomena in a time-dependent, three-dimensional model of an idealized eddy

    Science.gov (United States)

    Rypina, I. I.; Pratt, L. J.; Wang, P.; Äe; -zgökmen, T. M.; Mezic, I.

    2015-08-01

    We analyze the geometry of Lagrangian motion and material barriers in a time-dependent, three-dimensional, Ekman-driven, rotating cylinder flow, which serves as an idealization for an isolated oceanic eddy and other overturning cells with cylindrical geometry in the ocean and atmosphere. The flow is forced at the top through an oscillating upper lid, and the response depends on the frequency and amplitude of lid oscillations. In particular, the Lagrangian geometry changes near the resonant tori of the unforced flow, whose frequencies are rationally related to the forcing frequencies. Multi-scale analytical expansions are used to simplify the flow in the vicinity of resonant trajectories and to investigate the resonant flow geometries. The resonance condition and scaling can be motivated by simple physical argument. The theoretically predicted flow geometries near resonant trajectories have then been confirmed through numerical simulations in a phenomenological model and in a full solution of the Navier-Stokes equations.

  16. Rectifier Current Control for an LLC Resonant Converter Based on a Simplified Linearized Model

    Directory of Open Access Journals (Sweden)

    Zhijian Fang

    2018-03-01

    Full Text Available In this paper, a rectifier current control for an LLC resonant converter is proposed, based on a simplified, two-order, linearized model that adds a rectifier current feedback inner loop to improve dynamic performance. Compared to the traditional large-signal model with seven resonant states, this paper utilizes a rectifier current state to represent the characteristics of the resonant states, simplifying the LLC resonant model from seven orders to two orders. Then, the rectifier current feedback inner loop is proposed to increase the control system damping, improving dynamic performance. The modeling and design methodology for the LLC resonant converter are also presented in this paper. A frequency analysis is conducted to verify the accuracy of the simplified model. Finally, a 200 W LLC resonant converter prototype is built to verify the effectiveness of the proposed control strategy. Compared to a traditional single-loop controller, the settling time and voltage droop were reduced from 10.8 ms to 8.6 ms and from 6.8 V to 4.8 V, respectively, using the proposed control strategy.

  17. Continuum Modeling of Inductor Hysteresis and Eddy Current Loss Effects in Resonant Circuits

    Energy Technology Data Exchange (ETDEWEB)

    Pries, Jason L. [ORNL; Tang, Lixin [ORNL; Burress, Timothy A. [ORNL

    2017-10-01

    This paper presents experimental validation of a high-fidelity toroid inductor modeling technique. The aim of this research is to accurately model the instantaneous magnetization state and core losses in ferromagnetic materials. Quasi–static hysteresis effects are captured using a Preisach model. Eddy currents are included by coupling the associated quasi-static Everett function to a simple finite element model representing the inductor cross sectional area. The modeling technique is validated against the nonlinear frequency response from two different series RLC resonant circuits using inductors made of electrical steel and soft ferrite. The method is shown to accurately model shifts in resonant frequency and quality factor. The technique also successfully predicts a discontinuity in the frequency response of the ferrite inductor resonant circuit.

  18. A model of the transverse modes of stable and unstable porro-prism resonators using symmetry considerations

    Science.gov (United States)

    Burger, Liesl; Forbes, Andrew

    2007-09-01

    A simple model of a Porro prism laser resonator has been found to correctly predict the formation of the "petal" mode patterns typical of these resonators. A geometrical analysis of the petals suggests that these petals are the lowest-order modes of this type of resonator. Further use of the model reveals the formation of more complex beam patterns, and the nature of these patterns is investigated. Also, the output of stable and unstable resonator modes is presented.

  19. Transition polarizability model of induced resonance Raman optical activity

    Czech Academy of Sciences Publication Activity Database

    Yamamoto, S.; Bouř, Petr

    2013-01-01

    Roč. 34, č. 25 (2013), s. 2152-2158 ISSN 0192-8651 R&D Projects: GA ČR GAP208/11/0105; GA ČR GA13-03978S; GA MŠk(CZ) LH11033 Grant - others:AV ČR(CZ) M200551205 Institutional support: RVO:61388963 Keywords : induced resonance Raman optical activity * europium complexes * density functional computations * light scattering Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 3.601, year: 2013

  20. Physical optics modeling of modal patterns in a crossed porro prism resonator

    CSIR Research Space (South Africa)

    Litvin, IA

    2006-07-01

    Full Text Available A physical optics model is proposed to describe the transverse modal patterns in crossed Porro prism resonators. The model departs from earlier attempts in that the prisms are modeled as non-classical rotating elements with amplitude and phase...

  1. Random matrix approach to plasmon resonances in the random impedance network model of disordered nanocomposites

    Science.gov (United States)

    Olekhno, N. A.; Beltukov, Y. M.

    2018-05-01

    Random impedance networks are widely used as a model to describe plasmon resonances in disordered metal-dielectric and other two-component nanocomposites. In the present work, the spectral properties of resonances in random networks are studied within the framework of the random matrix theory. We have shown that the appropriate ensemble of random matrices for the considered problem is the Jacobi ensemble (the MANOVA ensemble). The obtained analytical expressions for the density of states in such resonant networks show a good agreement with the results of numerical simulations in a wide range of metal filling fractions 0

  2. Modeling and understanding of effects of randomness in arrays of resonant meta-atoms

    DEFF Research Database (Denmark)

    Tretyakov, Sergei A.; Albooyeh, Mohammad; Alitalo, Pekka

    2013-01-01

    In this review presentation we will discuss approaches to modeling and understanding electromagnetic properties of 2D and 3D lattices of small resonant particles (meta-atoms) in transition from regular (periodic) to random (amorphous) states. Nanostructured metasurfaces (2D) and metamaterials (3D......) are arrangements of optically small but resonant particles (meta-atoms). We will present our results on analytical modeling of metasurfaces with periodical and random arrangements of electrically and magnetically resonant meta-atoms with identical or random sizes, both for the normal and oblique-angle excitations....... We show how the electromagnetic response of metasurfaces is related to the statistical parameters of the structure. Furthermore, we will discuss the phenomenon of anti-resonance in extracted effective parameters of metamaterials and clarify its relation to the periodicity (or amorphous nature...

  3. Computer aided design of Langasite resonant cantilevers: analytical models and simulations

    Science.gov (United States)

    Tellier, C. R.; Leblois, T. G.; Durand, S.

    2010-05-01

    Analytical models for the piezoelectric excitation and for the wet micromachining of resonant cantilevers are proposed. Firstly, computations of metrological performances of micro-resonators allow us to select special cuts and special alignment of the cantilevers. Secondly the self-elaborated simulator TENSOSIM based on the kinematic and tensorial model furnishes etching shapes of cantilevers. As the result the number of selected cuts is reduced. Finally the simulator COMSOL® is used to evaluate the influence of final etching shape on metrological performances and especially on the resonance frequency. Changes in frequency are evaluated and deviating behaviours of structures with less favourable built-ins are tested showing that the X cut is the best cut for LGS resonant cantilevers vibrating in flexural modes (type 1 and type 2) or in torsion mode.

  4. A model for precalculus students to determine the resonance frequency of a trumpet mouthpiece

    Science.gov (United States)

    Chapman, Robert C.

    2004-05-01

    The trumpet mouthpiece as a Helmholtz resonator is used to show precalculus students a mathematical model for determining the approximate resonance frequency of the mouthpiece. The mathematics is limited to algebra and trigonometry. Using a system of mouthpieces that have interchangeable cups and backbores, students are introduced to the acoustics of this resonator. By gathering data on 51 different configurations of mouthpieces, the author modifies the existing Helmholtz resonator equation to account for both cup volumes and backbore configurations. Students then use this model for frequency predictions. Included are how to measure the different physical attributes of a trumpet mouthpiece at minimal cost. This includes methods for measuring cup volume, backbore volume, backbore length, throat area, etc. A portion of this phase is de-signed for students to become acquainted with some of the vocabulary of acoustics and the physics of sound.

  5. Texture zero neutrino models and their connection with resonant leptogenesis

    Science.gov (United States)

    Achelashvili, Avtandil; Tavartkiladze, Zurab

    2018-04-01

    Within the low scale resonant leptogenesis scenario, the cosmological CP asymmetry may arise by radiative corrections through the charged lepton Yukawa couplings. While in some cases, as one expects, decisive role is played by the λτ coupling, we show that in specific neutrino textures only by inclusion of the λμ the cosmological CP violation is generated at 1-loop level. With the purpose to relate the cosmological CP violation to the leptonic CP phase δ, we consider an extension of MSSM with two right handed neutrinos (RHN), which are degenerate in mass at high scales. Together with this, we first consider two texture zero 3 × 2 Dirac Yukawa matrices of neutrinos. These via see-saw generated neutrino mass matrices augmented by single ΔL = 2 dimension five (d = 5) operator give predictive neutrino sectors with calculable CP asymmetries. The latter is generated through λμ,τ coupling(s) at 1-loop level. Detailed analysis of the leptogenesis is performed. We also revise some one texture zero Dirac Yukawa matrices, considered earlier, and show that addition of a single ΔL = 2, d = 5 entry in the neutrino mass matrices, together with newly computed 1-loop corrections to the CP asymmetries, give nice accommodation of the neutrino sector and desirable amount of the baryon asymmetry via the resonant leptogenesis even for rather low RHN masses (∼few TeV-107 GeV).

  6. 77 FR 19967 - Safety Zone, Port of Dutch Harbor; Dutch Harbor, AK

    Science.gov (United States)

    2012-04-03

    ...-AA00 Safety Zone, Port of Dutch Harbor; Dutch Harbor, AK AGENCY: Coast Guard, DHS. ACTION: Notice of proposed rulemaking. SUMMARY: The Coast Guard proposes temporary safety zones in the Port of Dutch Harbor... Dutch Harbor, Alaska, and the adjacent territorial sea due to additional vessel traffic associated with...

  7. Mathematical Modeling of Resonant Processes in Confined Geometry of Atomic and Atom-Ion Traps

    Science.gov (United States)

    Melezhik, Vladimir S.

    2018-02-01

    We discuss computational aspects of the developed mathematical models for resonant processes in confined geometry of atomic and atom-ion traps. The main attention is paid to formulation in the nondirect product discrete-variable representation (npDVR) of the multichannel scattering problem with nonseparable angular part in confining traps as the boundary-value problem. Computational efficiency of this approach is demonstrated in application to atomic and atom-ion confinement-induced resonances we predicted recently.

  8. Roper resonances and generator coordinate method in the chiral-soliton model

    International Nuclear Information System (INIS)

    Meissner, T.; Gruemmer, F.; Goeke, K.; Harvey, M.

    1989-01-01

    The nucleon and Δ Roper resonances are described by means of the generator coordinate method in the framework of the nontopological chiral-soliton model. Solitons with various sizes are constructed with a constrained variational technique. The masses of all known Roper resonances come out to within 150 MeV of their experimental values. A nucleon compression modulus of about 4 GeV is extracted. The limits of the approach due to the polarization of the Dirac vacuum are displayed

  9. Army Engineers at Pearl Harbor

    Science.gov (United States)

    2011-01-01

    siblings, he was the grandson of David Belden Lyman—a Christian missionary from New England who settled in the Hilo , Hawaii area—and the descendent of...of Hawaii appeared over Oahu. Some headed for Ameri- can warships at Pearl Harbor and the planes on the ground at nearby Hickam Field; oth- ers...hit Schofield Barracks, Wheeler Field, and Bellows Field. USACE in Hawaii con- sisted of Soldier-engineers in the Army’s Hawaiian Depart- ment and

  10. Informational model verification of ZVS Buck quasi-resonant DC-DC converter

    Science.gov (United States)

    Vakovsky, Dimiter; Hinov, Nikolay

    2016-12-01

    The aim of the paper is to create a polymorphic informational model of a ZVS Buck quasi-resonant DC-DC converter for the modeling purposes of the object. For the creation of the model is applied flexible open standards for setting, storing, publishing and exchange of data in distributed information environment. The created model is useful for creation of many and different by type variants with different configuration of the composing elements and different inner model of the examined object.

  11. Ferromagnetic linewidth measurements employing electrodynamic model of the magnetic plasmon resonance

    Science.gov (United States)

    Krupka, Jerzy; Aleshkevych, Pavlo; Salski, Bartlomiej; Kopyt, Pawel

    2018-02-01

    The mode of uniform precession, or Kittel mode, in a magnetized ferromagnetic sphere, has recently been proven to be the magnetic plasmon resonance. In this paper we show how to apply the electrodynamic model of the magnetic plasmon resonance for accurate measurements of the ferromagnetic resonance linewidth ΔH. Two measurement methods are presented. The first one employs Q-factor measurements of the magnetic plasmon resonance coupled to the resonance of an empty metallic cavity. Such coupled modes are known as magnon-polariton modes, i.e. hybridized modes between the collective spin excitation and the cavity excitation. The second one employs direct Q-factor measurements of the magnetic plasmon resonance in a filter setup with two orthogonal semi-loops used for coupling. Q-factor measurements are performed employing a vector network analyser. The methods presented in this paper allow one to extend the measurement range of the ferromagnetic resonance linewidth ΔH well beyond the limits of the commonly used measurement standards in terms of the size of the samples and the lowest measurable linewidths. Samples that can be measured with the newly proposed methods may have larger size as compared to the size of samples that were used in the standard methods restricted by the limits of perturbation theory.

  12. Realistic Gamow shell model for resonance and continuum in atomic nuclei

    Science.gov (United States)

    Xu, F. R.; Sun, Z. H.; Wu, Q.; Hu, B. S.; Dai, S. J.

    2018-02-01

    The Gamow shell model can describe resonance and continuum for atomic nuclei. The model is established in the complex-moment (complex-k) plane of the Berggren coordinates in which bound, resonant and continuum states are treated on equal footing self-consistently. In the present work, the realistic nuclear force, CD Bonn, has been used. We have developed the full \\hat{Q}-box folded-diagram method to derive the realistic effective interaction in the model space which is nondegenerate and contains resonance and continuum channels. The CD-Bonn potential is renormalized using the V low-k method. With choosing 16O as the inert core, we have applied the Gamow shell model to oxygen isotopes.

  13. Vector and axial-vector resonances in composite models of the Higgs boson

    Energy Technology Data Exchange (ETDEWEB)

    Franzosi, Diogo Buarque [II. Physikalisches Institut, Universität Göttingen,Friedrich-Hund-Platz 1, 37077 Göttingen (Germany); Cacciapaglia, Giacomo; Cai, Haiying; Deandrea, Aldo [Univ Lyon, Université Lyon 1, CNRS/IN2P3, IPNL,F-69622, Villeurbanne (France); Frandsen, Mads [CP-Origins & Danish Institute for Advanced Study DIAS, University of Southern Denmark,Campusvej 55, DK-5230 Odense M (Denmark)

    2016-11-11

    We provide a non-linear realisation of composite Higgs models in the context of the SU(4)/Sp(4) symmetry breaking pattern, where the effective Lagrangian of the spin-0 and spin-1 resonances is constructed via the CCWZ prescription using the Hidden Symmetry formalism. We investigate the EWPT constraints by accounting the effects from reduced Higgs couplings and integrating out heavy spin-1 resonances. This theory emerges from an underlying theory of gauge interactions with fermions, thus first principle lattice results predict the massive spectrum in composite Higgs models. This model can be used as a template for the phenomenology of composite Higgs models at the LHC and at future 100 TeV colliders, as well as for other application. In this work, we focus on the formalism for spin-1 resonances and their bounds from di-lepton and di-boson searches at the LHC.

  14. Balanced sparse model for tight frames in compressed sensing magnetic resonance imaging.

    Directory of Open Access Journals (Sweden)

    Yunsong Liu

    Full Text Available Compressed sensing has shown to be promising to accelerate magnetic resonance imaging. In this new technology, magnetic resonance images are usually reconstructed by enforcing its sparsity in sparse image reconstruction models, including both synthesis and analysis models. The synthesis model assumes that an image is a sparse combination of atom signals while the analysis model assumes that an image is sparse after the application of an analysis operator. Balanced model is a new sparse model that bridges analysis and synthesis models by introducing a penalty term on the distance of frame coefficients to the range of the analysis operator. In this paper, we study the performance of the balanced model in tight frame based compressed sensing magnetic resonance imaging and propose a new efficient numerical algorithm to solve the optimization problem. By tuning the balancing parameter, the new model achieves solutions of three models. It is found that the balanced model has a comparable performance with the analysis model. Besides, both of them achieve better results than the synthesis model no matter what value the balancing parameter is. Experiment shows that our proposed numerical algorithm constrained split augmented Lagrangian shrinkage algorithm for balanced model (C-SALSA-B converges faster than previously proposed algorithms accelerated proximal algorithm (APG and alternating directional method of multipliers for balanced model (ADMM-B.

  15. Nonlinear behaviour of cantilevered carbon nanotube resonators based on a new nonlinear electrostatic load model

    Science.gov (United States)

    Farokhi, Hamed; Païdoussis, Michael P.; Misra, Arun K.

    2018-04-01

    The present study examines the nonlinear behaviour of a cantilevered carbon nanotube (CNT) resonator and its mass detection sensitivity, employing a new nonlinear electrostatic load model. More specifically, a 3D finite element model is developed in order to obtain the electrostatic load distribution on cantilevered CNT resonators. A new nonlinear electrostatic load model is then proposed accounting for the end effects due to finite length. Additionally, a new nonlinear size-dependent continuum model is developed for the cantilevered CNT resonator, employing the modified couple stress theory (to account for size-effects) together with the Kelvin-Voigt model (to account for nonlinear damping); the size-dependent model takes into account all sources of nonlinearity, i.e. geometrical and inertial nonlinearities as well as nonlinearities associated with damping, small-scale, and electrostatic load. The nonlinear equation of motion of the cantilevered CNT resonator is obtained based on the new models developed for the CNT resonator and the electrostatic load. The Galerkin method is then applied to the nonlinear equation of motion, resulting in a set of nonlinear ordinary differential equations, consisting of geometrical, inertial, electrical, damping, and size-dependent nonlinear terms. This high-dimensional nonlinear discretized model is solved numerically utilizing the pseudo-arclength continuation technique. The nonlinear static and dynamic responses of the system are examined for various cases, investigating the effect of DC and AC voltages, length-scale parameter, nonlinear damping, and electrostatic load. Moreover, the mass detection sensitivity of the system is examined for possible application of the CNT resonator as a nanosensor.

  16. Modelling and simulation of a thermally induced optical transparency in a dual micro-ring resonator.

    Science.gov (United States)

    Lydiate, Joseph

    2017-07-01

    This paper introduces the simulation and modelling of a novel dual micro-ring resonator. The geometric configuration of the resonators, and the implementation of a simulated broadband excitation source, results in the realization of optical transparencies in the combined through port output spectrum. The 130 nm silicon on insulator rib fabrication process is adopted for the simulation of the dual-ring configuration. Two titanium nitride heaters are positioned over the coupling regions of the resonators, which can be operated independently, to control the spectral position of the optical transparency. A third heater, centrally located above the dual resonator rings, can be used to red shift the entire spectrum to a required reference resonant wavelength. The free spectral range with no heater currents applied is 4.29 nm. For a simulated heater current of 7 mA (55.7 mW heater power) applied to one of the through coupling heaters, the optical transparency exhibits a red shift of 1.79 nm from the reference resonant wavelength. The ring-to-ring separation of approximately 900 nm means that it can be assumed that there is a zero ring-to-ring coupling field in this model. This novel arrangement has potential applications as a gas mass airflow sensor or a gas species identification sensor.

  17. Resonances and fusion in heavy ion reactions: new models and developments

    International Nuclear Information System (INIS)

    Cindro, N.

    1982-01-01

    Several aspects of the problem of the resonant behaviour of heavy-ion induced reactions are discussed. First, the problem is set in its relation to fundamental nuclear physics and our understanding of nuclear structure. It is suggested that, if the resonant behaviour of heavy-ion reactions is indeed due to the presence of particular configurations in the composite systems, these configurations must have a very specific nature which prevents their mixing with the adjacent states or else other conditons (e.g. low level density) should be met. Further on, the problem of resonant behaviour observed in back-angle elastic scattering and in forward-angle reaction data is discussed. Collisions between heavy ions leading to the composite systems 36 Ar and 40 Ca are used to discuss the apparent lack of correlation between these two sets of data. A way to understand it, based on the fragmentation of broad resonances, is suggested. In the third part the relation between structure in the fusion cross section excitation functions and that in reaction channel cross sections is discussed. Finally, in the fourth part, the orbiting-cluster model of heavy-ion resonances is briefly described and its predictions discussed. Based on this model a list is given of colliding heavy-ion systems where resonances are expected. (author)

  18. Theoretical model and optimization of a novel temperature sensor based on quartz tuning fork resonators

    International Nuclear Information System (INIS)

    Xu Jun; You Bo; Li Xin; Cui Juan

    2007-01-01

    To accurately measure temperatures, a novel temperature sensor based on a quartz tuning fork resonator has been designed. The principle of the quartz tuning fork temperature sensor is that the resonant frequency of the quartz resonator changes with the variation in temperature. This type of tuning fork resonator has been designed with a new doubly rotated cut work at flexural vibration mode as temperature sensor. The characteristics of the temperature sensor were evaluated and the results sufficiently met the target of development for temperature sensor. The theoretical model for temperature sensing has been developed and built. The sensor structure was analysed by finite element method (FEM) and optimized, including tuning fork geometry, tine electrode pattern and the sensor's elements size. The performance curve of output versus measured temperature is given. The results from theoretical analysis and experiments indicate that the sensor's sensitivity can reach 60 ppm 0 C -1 with the measured temperature range varying from 0 to 100 0 C

  19. Non-monotonic resonance in a spatially forced Lengyel-Epstein model

    Energy Technology Data Exchange (ETDEWEB)

    Haim, Lev [Physics Department, Ben-Gurion University of the Negev, Beer-Sheva 84105 (Israel); Department of Oncology, Soroka University Medical Center, Beer-Sheva 84101 (Israel); Hagberg, Aric [Center for Nonlinear Studies, Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States); Meron, Ehud [Physics Department, Ben-Gurion University of the Negev, Beer-Sheva 84105 (Israel); Department of Solar Energy and Environmental Physics, BIDR, Ben-Gurion University of the Negev, Sede Boqer Campus, Midreshet Ben-Gurion 84990 (Israel)

    2015-06-15

    We study resonant spatially periodic solutions of the Lengyel-Epstein model modified to describe the chlorine dioxide-iodine-malonic acid reaction under spatially periodic illumination. Using multiple-scale analysis and numerical simulations, we obtain the stability ranges of 2:1 resonant solutions, i.e., solutions with wavenumbers that are exactly half of the forcing wavenumber. We show that the width of resonant wavenumber response is a non-monotonic function of the forcing strength, and diminishes to zero at sufficiently strong forcing. We further show that strong forcing may result in a π/2 phase shift of the resonant solutions, and argue that the nonequilibrium Ising-Bloch front bifurcation can be reversed. We attribute these behaviors to an inherent property of forcing by periodic illumination, namely, the increase of the mean spatial illumination as the forcing amplitude is increased.

  20. RECONSTRUCTION OF A HUMAN LUNG MORPHOLOGY MODEL FROM MAGNETIC RESONANCE IMAGES

    Science.gov (United States)

    RATIONALE A description of lung morphological structure is necessary for modeling the deposition and fate of inhaled therapeutic aerosols. A morphological model of the lung boundary was generated from magnetic resonance (MR) images with the goal of creating a framework for anato...

  1. COMPUTER RECONSTRUCTION OF A HUMAN LUNG MORPHOLOGY MODEL FROM MAGNETIC RESONANCE (MR) IMAGES

    Science.gov (United States)

    A mathematical description of the morphological structure of the lung is necessary for modeling and analysis of the deposition of inhaled aerosols. A morphological model of the lung boundary was generated from magnetic resonance (MR) images, with the goal of creating a frame...

  2. A collective model description of the low lying and giant dipole resonant properties of 40424446Ca

    International Nuclear Information System (INIS)

    Weise, J.I.

    1982-01-01

    The low-lying and giant dipole resonant properties of the even-even calcium isotopes are calculated within the framework of the Gneuss-Greiner model and compared with the experimental data. In the low energy region, comparison is also made with the predictions of a coexistence model

  3. Modeling dendrite density from magnetic resonance diffusion measurements

    DEFF Research Database (Denmark)

    Jespersen, Sune Nørhøj; Kroenke, CD; Østergaard, Leif

    2007-01-01

    in this model: (i) the dendrites and axons, which are modeled as long cylinders with two diffusion coefficients, parallel (DL) and perpendicular (DT) to the cylindrical axis, and (ii) an isotropic monoexponential diffusion component describing water diffusion within and across all other structures, i.......e., in extracellular space and glia cells. The model parameters are estimated from 153 diffusion-weighted images acquired from a formalin-fixed baboon brain. A close correspondence between the data and the signal model is found, with the model parameters consistent with literature values. The model provides......Diffusion-weighted imaging (DWI) provides a noninvasive tool to probe tissue microstructure. We propose a simplified model of neural cytoarchitecture intended to capture the essential features important for water diffusion as measured by NMR. Two components contribute to the NMR signal...

  4. SMATASY. A Program for the model independent description of the Z resonance

    International Nuclear Information System (INIS)

    Kirsch, S.; Riemann, T.

    1994-07-01

    SMATASY is an interface for the ZF I T T ER package and may be used for the model independent description of the Z resonance at LEP 1 and SLC. It allows the determination of the Z mass and width and its resonance shape parameters r and j for cross-sections and their asymmetries. The r describes the peak height and j the interference of the Z resonance with photon exchange in each scattering channel and for σ T , σ FB , σ lr , σ pol etc. separately. Alternatively, the helicity amplitudes for a given scattering channel may be determined. We compare our formalism with other model independent approaches. The model independent treatment of QED corrections in SMATASY is applicable also far away from the Z peak. (orig.)

  5. Modeling the diffusion magnetic resonance imaging signal inside neurons

    International Nuclear Information System (INIS)

    Nguyen, D V; Li, J R; Grebenkov, D S; Le Bihan, D

    2014-01-01

    The Bloch-Torrey partial differential equation (PDE) describes the complex transverse water proton magnetization due to diffusion-encoding magnetic field gradient pulses. The integral of the solution of this PDE yields the diffusion magnetic resonance imaging (dMRI) signal. In a complex medium such as cerebral tissue, it is difficult to explicitly link the dMRI signal to biological parameters such as the cellular geometry or the cellular volume fraction. Studying the dMRI signal arising from a single neuron can provide insight into how the geometrical structure of neurons influences the measured signal. We formulate the Bloch-Torrey PDE inside a single neuron, under no water exchange condition with the extracellular space, and show how to reduce the 3D simulation in the full neuron to a 3D simulation around the soma and 1D simulations in the neurites. We show that this latter approach is computationally much faster than full 3D simulation and still gives accurate results over a wide range of diffusion times

  6. An analytical model for the determination of resonance frequencies of perforated beams

    International Nuclear Information System (INIS)

    Luschi, Luca; Pieri, Francesco

    2014-01-01

    In this paper, we develop closed expressions for the equivalent bending and shear stiffness of beams with regular square perforations, and apply them to the problem of determining the resonance frequencies of slender, regularly perforated clamped–clamped beams, which are of interest in the development of MEMS resonant devices. We prove that, depending on the perforation size, the Euler–Bernoulli equation or the more complex shear equation needs to be used to obtain accurate values for these frequencies. Extensive finite element method simulations are used to validate the proposed model over the full practical range of possible hole sizes. An experimental verification of the model is also presented. (paper)

  7. Rescaled Local Interaction Simulation Approach for Shear Wave Propagation Modelling in Magnetic Resonance Elastography

    Directory of Open Access Journals (Sweden)

    Z. Hashemiyan

    2016-01-01

    Full Text Available Properties of soft biological tissues are increasingly used in medical diagnosis to detect various abnormalities, for example, in liver fibrosis or breast tumors. It is well known that mechanical stiffness of human organs can be obtained from organ responses to shear stress waves through Magnetic Resonance Elastography. The Local Interaction Simulation Approach is proposed for effective modelling of shear wave propagation in soft tissues. The results are validated using experimental data from Magnetic Resonance Elastography. These results show the potential of the method for shear wave propagation modelling in soft tissues. The major advantage of the proposed approach is a significant reduction of computational effort.

  8. Rescaled Local Interaction Simulation Approach for Shear Wave Propagation Modelling in Magnetic Resonance Elastography

    Science.gov (United States)

    Packo, P.; Staszewski, W. J.; Uhl, T.

    2016-01-01

    Properties of soft biological tissues are increasingly used in medical diagnosis to detect various abnormalities, for example, in liver fibrosis or breast tumors. It is well known that mechanical stiffness of human organs can be obtained from organ responses to shear stress waves through Magnetic Resonance Elastography. The Local Interaction Simulation Approach is proposed for effective modelling of shear wave propagation in soft tissues. The results are validated using experimental data from Magnetic Resonance Elastography. These results show the potential of the method for shear wave propagation modelling in soft tissues. The major advantage of the proposed approach is a significant reduction of computational effort. PMID:26884808

  9. Partial widths of boson resonances in the quark-gluon model of strong interactions

    International Nuclear Information System (INIS)

    Kaidalov, A.B.; Volkovitsky, P.E.

    1981-01-01

    The quark-gluon model of strong interactions based on the topological expansion and the string model ib used for the calculation of the partial widths of boson resonances in the channels with two pseudoscalar mesons. The partial widths of mesons with arbitrary spins lying on the vector and tensor Regge trajectories are expressed in terms of the only rho-meson width. The violation of SU(3) symmetry increases with the growth of the spin of the resonance. The theoretical predictions are in a good agreement with experimental data [ru

  10. Competition model for aperiodic stochastic resonance in a Fitzhugh-Nagumo model of cardiac sensory neurons.

    Science.gov (United States)

    Kember, G C; Fenton, G A; Armour, J A; Kalyaniwalla, N

    2001-04-01

    Regional cardiac control depends upon feedback of the status of the heart from afferent neurons responding to chemical and mechanical stimuli as transduced by an array of sensory neurites. Emerging experimental evidence shows that neural control in the heart may be partially exerted using subthreshold inputs that are amplified by noisy mechanical fluctuations. This amplification is known as aperiodic stochastic resonance (ASR). Neural control in the noisy, subthreshold regime is difficult to see since there is a near absence of any correlation between input and the output, the latter being the average firing (spiking) rate of the neuron. This lack of correlation is unresolved by traditional energy models of ASR since these models are unsuitable for identifying "cause and effect" between such inputs and outputs. In this paper, the "competition between averages" model is used to determine what portion of a noisy, subthreshold input is responsible, on average, for the output of sensory neurons as represented by the Fitzhugh-Nagumo equations. A physiologically relevant conclusion of this analysis is that a nearly constant amount of input is responsible for a spike, on average, and this amount is approximately independent of the firing rate. Hence, correlation measures are generally reduced as the firing rate is lowered even though neural control under this model is actually unaffected.

  11. 33 CFR 125.15 - Access to waterfront facilities, and port and harbor areas, including vessels and harbor craft...

    Science.gov (United States)

    2010-07-01

    ..., and port and harbor areas, including vessels and harbor craft therein. 125.15 Section 125.15....15 Access to waterfront facilities, and port and harbor areas, including vessels and harbor craft....09 to those waterfront facilities, and port and harbor areas, including vessels and harbor craft...

  12. The stochastic resonance for the incidence function model of metapopulation

    Science.gov (United States)

    Li, Jiang-Cheng; Dong, Zhi-Wei; Zhou, Ruo-Wei; Li, Yun-Xian; Qian, Zhen-Wei

    2017-06-01

    A stochastic model with endogenous and exogenous periodicities is proposed in this paper on the basis of metapopulation dynamics to model the crop yield losses due to pests and diseases. The rationale is that crop yield losses occur because the physiology of the growing crop is negatively affected by pests and diseases in a dynamic way over time as crop both grows and develops. Metapopulation dynamics can thus be used to model the resultant crop yield losses. The stochastic metapopulation process is described by using the Simplified Incidence Function model (IFM). Compared to the original IFMs, endogenous and exogenous periodicities are considered in the proposed model to handle the cyclical patterns observed in pest infestations, diseases epidemics, and exogenous affecting factors such as temperature and rainfalls. Agricultural loss data in China are used to fit the proposed model. Experimental results demonstrate that: (1) Model with endogenous and exogenous periodicities is a better fit; (2) When the internal system fluctuations and external environmental fluctuations are negatively correlated, EIL or the cost of loss is monotonically increasing; when the internal system fluctuations and external environmental fluctuations are positively correlated, an outbreak of pests and diseases might occur; (3) If the internal system fluctuations and external environmental fluctuations are positively correlated, an optimal patch size can be identified which will greatly weaken the effects of external environmental influence and hence inhibit pest infestations and disease epidemics.

  13. Model of charge-state distributions for electron cyclotron resonance ion source plasmas

    Directory of Open Access Journals (Sweden)

    D. H. Edgell

    1999-12-01

    Full Text Available A computer model for the ion charge-state distribution (CSD in an electron cyclotron resonance ion source (ECRIS plasma is presented that incorporates non-Maxwellian distribution functions, multiple atomic species, and ion confinement due to the ambipolar potential well that arises from confinement of the electron cyclotron resonance (ECR heated electrons. Atomic processes incorporated into the model include multiple ionization and multiple charge exchange with rate coefficients calculated for non-Maxwellian electron distributions. The electron distribution function is calculated using a Fokker-Planck code with an ECR heating term. This eliminates the electron temperature as an arbitrary user input. The model produces results that are a good match to CSD data from the ANL-ECRII ECRIS. Extending the model to 1D axial will also allow the model to determine the plasma and electrostatic potential profiles, further eliminating arbitrary user input to the model.

  14. The J3 SCR model applied to resonant converter simulation

    Science.gov (United States)

    Avant, R. L.; Lee, F. C. Y.

    1985-01-01

    The J3 SCR model is a continuous topology computer model for the SCR. Its circuit analog and parameter estimation procedure are uniformly applicable to popular computer-aided design and analysis programs such as SPICE2 and SCEPTRE. The circuit analog is based on the intrinsic three pn junction structure of the SCR. The parameter estimation procedure requires only manufacturer's specification sheet quantities as a data base.

  15. Determination of freeze-out conditions from fluctuations in the Hadron Resonance Gas model

    International Nuclear Information System (INIS)

    Alba, P; Alberico, W; Sarti, V Mantovani; Ratti, C; Bellwied, R; Bluhm, M; Nahrgang, M

    2015-01-01

    Fluctuations of conserved charges measured in Heavy-Ion Collisions (HICs) received increasing attention in recent years, because they are good candidates to explore the phase diagram of QCD matter. During the last year, net-electric charge and net-proton moments of multiplicities measured at RHIC have been published by the STAR collaboration, for a range of collision energies which spans a region of the phase diagram at finite chemical potential. Here we present a new freeze-out curve obtained using the Hadron Resonance Gas (HRG) model approach to fit these experimental data. The HRG model is modified in order to have a realistic description of the HICs: kinematic cuts, resonance feed-down and resonance regeneration are taken into account. Our result is in agreement with preliminary studies by the ALICE collaboration, and is supported by a recent lattice analysis of the same quantities. (paper)

  16. Vector and Axial-vector resonances in composite models of the Higgs boson

    DEFF Research Database (Denmark)

    Franzosi, Diogo Buarque; Cacciapaglia, Giacomo; Cai, Haiying

    2016-01-01

    We provide a non-linear realisation of composite Higgs models in the context of the SU(4)/Sp(4) symmetry breaking pattern, where the effective Lagrangian of the spin-0 and spin-1 resonances is constructed via the CCWZ prescription using the Hidden Symmetry formalism. We investigate the EWPT const...... as a template for the phenomenology of composite Higgs models at the LHC and at future 100 TeV colliders, as well as for other application. In this work, we focus on the formalism for spin-1 resonances and their bounds from di-lepton and di-boson searches at the LHC.......We provide a non-linear realisation of composite Higgs models in the context of the SU(4)/Sp(4) symmetry breaking pattern, where the effective Lagrangian of the spin-0 and spin-1 resonances is constructed via the CCWZ prescription using the Hidden Symmetry formalism. We investigate the EWPT...... constraints by accounting the effects from reduced Higgs couplings and integrating out heavy spin-1 resonances. This theory emerges from an underlying theory of gauge interactions with fermions, thus first principle lattice results predict the massive spectrum in composite Higgs models. This model can be used...

  17. Transmission line model for coupled rectangular double split‐ring resonators

    DEFF Research Database (Denmark)

    Yan, Lei; Tang, Meng; Krozer, Viktor

    2011-01-01

    In this work, a model based on a coupled transmission line formulation is developed for microstrip rectangular double split‐ring resonators (DSRRs). This model allows using the physical dimensions of the DSRRs as an input avoiding commonly used extraction of equivalent parameters. The model inclu...... simulations of the DSRR structures. © 2011 Wiley Periodicals, Inc. Microwave Opt Technol Lett 53:1311–1315, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.25988...

  18. Prediction of multiple resonance characteristics by an extended resistor-inductor-capacitor circuit model for plasmonic metamaterials absorbers in infrared.

    Science.gov (United States)

    Xu, Xiaolun; Li, Yongqian; Wang, Binbin; Zhou, Zili

    2015-10-01

    The resonance characteristics of plasmonic metamaterials absorbers (PMAs) are strongly dependent on geometric parameters. A resistor-inductor-capacitor (RLC) circuit model has been extended to predict the resonance wavelengths and the bandwidths of multiple magnetic polaritons modes in PMAs. For a typical metallic-dielectric-metallic structure absorber working in the infrared region, the developed model describes the correlation between the resonance characteristics and the dimensional sizes. In particular, the RLC model is suitable for not only the fundamental resonance mode, but also for the second- and third-order resonance modes. The prediction of the resonance characteristics agrees fairly well with those calculated by the finite-difference time-domain simulation and the experimental results. The developed RLC model enables the facilitation of designing multi-band PMAs for infrared radiation detectors and thermal emitters.

  19. CRSMP Potential Harbor Borrow Sites 2012

    Data.gov (United States)

    California Natural Resource Agency — Harbor locations as identified originally in the California Shoreline Database compiled by Noble Consultants (Jon Moore) for California Department of Boating and...

  20. Iota-dependent resonance absorption in the optical model description of alpha particle elastic scattering

    International Nuclear Information System (INIS)

    Chyla, K.; Jarczyk, L.; Maciuk, B.; Zipper, W.

    1976-01-01

    Alpha particle scattering from 28 Si has been studied at five bombarding energies from 23.5 to 28.5 MeV. iota-dependent resonance absorption has been introduced to the optical model analysis of 28 Si (α,β) 28 Si reaction. (author)

  1. Modeling the Influence of Piriform Sinuses and Valleculae on the Vocal Tract Resonances and Antiresonances

    Czech Academy of Sciences Publication Activity Database

    Vampola, T.; Horáček, Jaromír; Švec, J. G.

    2015-01-01

    Roč. 101, č. 3 (2015), s. 594-602 ISSN 1610-1928 R&D Projects: GA ČR(CZ) GAP101/12/1306 Institutional support: RVO:61388998 Keywords : biomechanics of voice * higher acoustic resonances in human vocal tract * reduced FE model of the vocal tract Subject RIV: BI - Acoustics Impact factor: 0.897, year: 2015

  2. Modeling of Nanophotonic Resonators with the Finite-Difference Frequency-Domain Method

    DEFF Research Database (Denmark)

    Ivinskaya, Aliaksandra; Lavrinenko, Andrei; Shyroki, Dzmitry

    2011-01-01

    Finite-difference frequency-domain method with perfectly matched layers and free-space squeezing is applied to model open photonic resonators of arbitrary morphology in three dimensions. Treating each spatial dimension independently, nonuniform mesh of continuously varying density can be built ea...

  3. Wave packet formulation of the boomerang model for resonant electron--molecule scattering

    International Nuclear Information System (INIS)

    McCurdy, C.W.; Turner, J.L.

    1983-01-01

    A time-dependent formulation of the boomerang model for resonant electron--molecule scattering is presented in terms of a wave packet propagating on the complex potential surface of the metastable anion. The results of calculations using efficient semiclassical techniques for propagating the wave packet are found to be in excellent agreement with full quantum-mechanical calculations of vibrational excitation cross sections in e - --N 2 scattering. The application of the wave packet formulation as a computational and conceptual approach to the problem of resonant collisions with polyatomic molecules is discussed in the light of recent wave packet calculations on polyatomic photodissociation and Raman spectra

  4. Information transfer with rate-modulated Poisson processes: a simple model for nonstationary stochastic resonance.

    Science.gov (United States)

    Goychuk, I

    2001-08-01

    Stochastic resonance in a simple model of information transfer is studied for sensory neurons and ensembles of ion channels. An exact expression for the information gain is obtained for the Poisson process with the signal-modulated spiking rate. This result allows one to generalize the conventional stochastic resonance (SR) problem (with periodic input signal) to the arbitrary signals of finite duration (nonstationary SR). Moreover, in the case of a periodic signal, the rate of information gain is compared with the conventional signal-to-noise ratio. The paper establishes the general nonequivalence between both measures notwithstanding their apparent similarity in the limit of weak signals.

  5. Anomalous resonance of the symmetric single-impurity Anderson model in the presence of pairing fluctuations

    International Nuclear Information System (INIS)

    Guang-Ming Zhang; Lu Yu

    1998-10-01

    We consider the symmetric single-impurity Anderson model in the presence of pairing fluctuations. In the isotropic limit, the degrees of freedom of the local impurity are separated into hybridizing and non-hybridizing modes. The self-energy for the hybridizing modes can be obtained exactly, leading to two subbands centered at ±U/2. For the non-hybridizing modes, the second order perturbation yields a singular resonance of the marginal Fermi liquid form. By multiplicative renormalization, the self-energy is derived exactly, showing the resonance is pinned at the Fermi level, while its strength is weakened by renormalization. (author)

  6. Optical model calculation for the unresolved/resolved resonance region of Fe-56

    Energy Technology Data Exchange (ETDEWEB)

    Kawano, Toshihiko [Kyushu Univ., Fukuoka (Japan); Froehner, F.H.

    1997-03-01

    We have studied optical model fits to total neutron cross sections of structural materials using the accurate data base for {sup 56}Fe existing in the resolved and unresolved resonance region. Averages over resolved resonances were calculated with Lorentzian weighting in Reich-Moore (reduced R matrix) approximation. Starting from the best available optical potentials we found that adjustment of the real and imaginary well depths does not work satisfactorily with the conventional weak linear energy dependence of the well depths. If, however, the linear dependences are modified towards low energies, the average total cross sections can be fitted quite well, from the resolved resonance region up to 20 MeV and higher. (author)

  7. Electromechanical model of a resonating nano-cantilever-based sensor for high-resolution and high-sensitivity mass detection

    DEFF Research Database (Denmark)

    Abadal, G.; Davis, Zachary James; Helbo, Bjarne

    2001-01-01

    A simple linear electromechanical model for an electrostatically driven resonating cantilever is derived. The model has been developed in order to determine dynamic quantities such as the capacitive current flowing through the cantilever-driver system at the resonance frequency, and it allows us ...

  8. Multi-Criteria Decision-Making Model for the Material Flow of Resonant Wood Production

    Directory of Open Access Journals (Sweden)

    Patrik Aláč

    2017-03-01

    Full Text Available This paper proposes a multi-criteria decision-making model, for the selection and evaluation of the most valuable wooden input—resonant wood. Application of a given model can improve the process of input valuation as well as impact and improve particular economic indicators for the resonant wood manufacturer. We have tried to describe and evaluate the supply chain of resonant wood manufacturing and production of musical instruments. Particular value-added and non-value-added activities have been chosen according to the logical sequence of technology. Then, concrete criteria were specified and their significance weightings. Another important part of our paper is the description of resonant wood, specifications, and demands on log and wood species. There are some important physical and mechanical properties which should be taken into account and evaluated during the production of musical instruments. By the application of this model, a particular enterprise can reach an enhanced tool for the continuous evaluation of the product flowing through the supply chain. Visibility of particular operations and their logical sequence, presented by Petri nets, can lead to easier detection of possible defects in these operations and their origin. So, the main purpose of the paper lies in the suggestion of an objective and quantified managerial tool for the decision making.

  9. 33 CFR 100.109 - Winter Harbor Lobster Boat Race, Winter Harbor, ME.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Winter Harbor Lobster Boat Race, Winter Harbor, ME. 100.109 Section 100.109 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.109 Winter Harbor...

  10. Asymptotically exact solution of the multi-channel resonant-level model

    International Nuclear Information System (INIS)

    Zhang Guangming; Su Zhaobin; Yu Lu.

    1994-01-01

    An asymptotically exact partition function of the multi-channel resonant-level model is obtained through Tomonaga-Luttinger bosonization. A Fermi-liquid vs. non-Fermi-liquid transition, resulting from a competition between the Kondo and X-ray edge physics, is elucidated explicitly via the renormalization group theory. In the strong-coupling limit, the model is renormalized to the Toulouse limit. (author). 20 refs, 1 fig

  11. Modelling the dynamic mechanisms associated with the principal resonance of the seated human body.

    Science.gov (United States)

    Matsumoto, Y; Griffin, M J

    2001-01-01

    Simple mathematical models have been developed to obtain insights into resonance phenomena observed at about 5 Hz in the dynamic responses of the seated human body exposed to vertical whole-body vibration. Alternative lumped parameter models with a few degrees-of-freedom have been investigated. Rotational degrees-of-freedom, with eccentricity of the centre of gravity of the mass elements, represented responses in the fore-and-aft and pitch axes caused by vertical vibration. The causes of body resonance are not fully understood, but this information is required to develop cause-effect relationships between vibration exposures and effects on human health, comfort and performance.Method. The inertial and geometric parameters for models were based on published anatomical data. Other mechanical parameters were determined by comparing model responses to experimental data. Two models, with four and five degrees-of-freedom, gave more reasonable representations than other models. Mechanical parameters obtained with median and individual experimental data were consistent for vertical degrees-of-freedom but varied for rotational degrees-of-freedom. The resonance of the apparent mass at about 5 Hz may be attributed to a vibration mode consisting of vertical motion of the pelvis and legs and a pitch motion of the pelvis, both of which cause vertical motion of the upper-body above the pelvis, a bending motion of the spine, and vertical motion of the viscera. The mathematical models developed in this study may assist understanding of the dynamic mechanisms responsible for resonances in the seated human body. The information is required to represent mechanical responses of the body and assist the development of models for specific effects of vibration.

  12. Pionic corrections to the MIT bag model: The (3,3) resonance

    International Nuclear Information System (INIS)

    Theberge, S.; Thomas, A.W.; Miller, G.A.

    1980-01-01

    By incorporating chiral invariance in the MIT bag model, we are led to a theory in which the pion field is coupled to the confined quarks only at the bag surface. An equivalent quantized theory of nucleons and Δ's interacting with pions is then obtained. The pion-nucleon scattering amplitude in this model is found to give a good fit to experimental data on the (3,3) resonance, with a bag radius of about 0.72 fm

  13. QCD mixing effects in a gauge invariant quark model for photo- and electroproduction of baryon resonances

    International Nuclear Information System (INIS)

    Zhenping Li; Close, F.E.

    1990-03-01

    The photo and electroproduction of baryon resonances has been calculated using the Constituent Quark Model with chromodynamics consistent with O(υ 2 /c 2 ) for the quarks. We find that the successes of the nonrelativistic quark model are preserved, some problems are removed and that QCD mixing effects may become important with increasing q 2 in electroproduction. For the first time both spectroscopy and transitions receive a unified treatment with a single set of parameters. (author)

  14. Nonlinear aeroacoustic characterization of Helmholtz resonators with a local-linear neuro-fuzzy network model

    Science.gov (United States)

    Förner, K.; Polifke, W.

    2017-10-01

    The nonlinear acoustic behavior of Helmholtz resonators is characterized by a data-based reduced-order model, which is obtained by a combination of high-resolution CFD simulation and system identification. It is shown that even in the nonlinear regime, a linear model is capable of describing the reflection behavior at a particular amplitude with quantitative accuracy. This observation motivates to choose a local-linear model structure for this study, which consists of a network of parallel linear submodels. A so-called fuzzy-neuron layer distributes the input signal over the linear submodels, depending on the root mean square of the particle velocity at the resonator surface. The resulting model structure is referred to as an local-linear neuro-fuzzy network. System identification techniques are used to estimate the free parameters of this model from training data. The training data are generated by CFD simulations of the resonator, with persistent acoustic excitation over a wide range of frequencies and sound pressure levels. The estimated nonlinear, reduced-order models show good agreement with CFD and experimental data over a wide range of amplitudes for several test cases.

  15. The Suez Canal and the petroleum harbors

    International Nuclear Information System (INIS)

    Anon.

    1997-01-01

    The Suez Canal is the second longest channel in the world and allows to save 60% of the travel time between the petroleum harbors of the Arabic peninsula and Europe. This short paper gives a summary of the main petroleum harbors activity along the channel from the Red sea to the Mediterranean sea. (J.S.)

  16. Charleston Harbor, SC, Regional Sediment Management Study: Beneficial Use of Dredged Material through Nearshore Placement

    Science.gov (United States)

    2017-05-01

    Modeling System (CMS) that were developed and applied previously for the Charleston Harbor numerical modeling study (Kashlan 2013) were used in...Particle Tracking Model; Report 1: Model theory, implementation, and example applications. ERDC/CHL TR-6-20. Vicksburg, MS: U.S. Army Engineer Research ...ER D C/ CH L TR -1 7- 7 Regional Sediment Management (RSM) Program Charleston Harbor, SC, Regional Sediment Management Study

  17. Charleston Harbor, SC, Regional Sediment Management Study; Beneficial Use of Dredged Material through Nearshore Placement

    Science.gov (United States)

    2017-05-01

    Modeling System (CMS) that were developed and applied previously for the Charleston Harbor numerical modeling study (Kashlan 2013) were used in...Particle Tracking Model; Report 1: Model theory, implementation, and example applications. ERDC/CHL TR-6-20. Vicksburg, MS: U.S. Army Engineer Research ...ER D C/ CH L TR -1 7- 7 Regional Sediment Management (RSM) Program Charleston Harbor, SC, Regional Sediment Management Study

  18. Modelling out-of-plane and in-plane resonant modes of microplates in liquid media

    International Nuclear Information System (INIS)

    Ruiz-Díez, V; Hernando-García, J; Manzaneque, T; Sánchez-Rojas, J L; Kucera, M; Schmid, U

    2015-01-01

    In this article, the quality factor and the resonant frequency of different vibrating modes of microplates immersed in liquid are simulated by means of a finite element method (FEM) and compared with experimental data. For the in-plane modes, we studied the first extensional mode of mid-point supported microplates, which may be efficiently actuated by a thin piezoelectric film on top of the structure. A comparison of different approaches to account for the viscous loading in computationally efficient 2D finite element models is presented. As an alternative to the harmonic response, a novel multitone excitation in the fluid–structure interaction model allows for the calculation of the frequency response of the structure. For the out-of-plane modes, different modes were simulated and compared to analytical models to validate our approach. Our 2D FEM model yields more accurate estimations of the experimental resonance frequency and quality factors than the available analytical models. With the help of these tools, the applicability of the micro-resonators as viscosity and density sensors is discussed. (paper)

  19. Dynamical response of multi-walled carbon nanotube resonators based on continuum mechanics modeling for mass sensing applications

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Myungseok; Olshevskiy, Alexander; Kim, Chang-Wan [Konkuk University, Seoul (Korea, Republic of); Eom, Kilho [Sungkyunkwan University, Suwon (Korea, Republic of); Gwak, Kwanwoong [Sejong University, Seoul (Korea, Republic of); Dai, Mai Duc [Ho Chi Minh City University of Technology and Education, Ho Chi Minh (Viet Nam)

    2017-05-15

    Carbon nanotube (CNT) has recently received much attention due to its excellent electromechanical properties, indicating that CNT can be employed for development of Nanoelectromechanical system (NEMS) such as nanomechanical resonators. For effective design of CNT-based resonators, it is required to accurately predict the vibration behavior of CNT resonators as well as their frequency response to mass adsorption. In this work, we have studied the vibrational behavior of Multi-walled CNT (MWCNT) resonators by using a continuum mechanics modeling that was implemented in Finite element method (FEM). In particular, we consider a transversely isotropic hollow cylinder solid model with Finite element (FE) implementation for modeling the vibration behavior of Multi-walled CNT (MWCNT) resonators. It is shown that our continuum mechanics model provides the resonant frequencies of various MWCNTs being comparable to those obtained from experiments. Moreover, we have investigated the frequency response of MWCNT resonators to mass adsorption by using our continuum model with FE implementation. Our study sheds light on our continuum mechanics model that is useful in predicting not only the vibration behavior of MWCNT resonators but also their sensing performance for further effective design of MWCNT- based NEMS devices.

  20. Validity of the electrical model representation of the effects of nuclear magnetic resonance (1961); Validite de la representation par modele electrique des effets de resonance magnetique nucleaire (1961)

    Energy Technology Data Exchange (ETDEWEB)

    Bonnet, G [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1961-07-01

    When studying the behaviour of a magnetic resonance transducer formed by the association of an electrical network and of a set of nuclear spins, it is possible to bring about a representation that is analytically equivalent by means of an entirely electrical model, available for transients as well as steady-state. A detailed study of the validity conditions justifies its use in most cases. Also proposed is a linearity criterion of Bloch's equations in transient state that is simply the prolongation of the well-known condition of non-saturation in the steady-state. (author) [French] L'etude du comportement d'un transducteur a resonance magnetique forme de l'association d'un reseau electrique et d'un ensemble de noyaux dotes de spin, montre qu'il est possible d'en deduire une representation analytiquement equivalente au moyen d'un modele entierement electrique utilisable pour un regime transitoire aussi bien que pour un regime permanent. Une etude detaillee des conditions de validite permet d'en justifier l'emploi dans la majorite des cas. On propose enfin un critere de linearite des equations de Bloch en regime transitoire, qui constitue un prolongement de la condition connue de non-saturation en regime stationnaire. (auteur)

  1. Synthetic model for Doppler broadening of neutron absorption resonances in molecular fluids

    Energy Technology Data Exchange (ETDEWEB)

    Villanueva, Alejandro J., E-mail: villanueva@cab.cnea.gov.a [Comision Nacional de Energia Atomica, Centro Atomico Bariloche and Instituto Balseiro, 8400 S.C. de Bariloche (RN) (Argentina); Consejo Nacional de Investigaciones Cientificas y Tecnicas (Argentina); Granada, J.R. [Comision Nacional de Energia Atomica, Centro Atomico Bariloche and Instituto Balseiro, 8400 S.C. de Bariloche (RN) (Argentina); Consejo Nacional de Investigaciones Cientificas y Tecnicas (Argentina)

    2010-08-15

    A general and systematic approach expressed in modern language, accounting for molecular motion effects on Doppler Broadening of Neutron Absorption Resonances (DBNAR) is given the form of a new model. It relies on well validated hypothesis: The separability of atomic from nuclear degrees of freedom, the use of the Van Hove scattering formalism and the fact that a conceptually identical approach produced experimentally proved predictions when applied to DBNAR in solid systems. We treat the molecular internal degrees of freedom approximately as harmonic oscillators. As a second contribution of this work, a synthetic model is presented in order to make the more complete model mentioned above suitable for neutron calculation codes. This second synthetic model reduces to the exact expressions of the complete model in the low and high neutron energy regimes and provides a plausible transition in between. Numerical results are presented for a general hypothetical case to show its strengths and limitations. Also, both models are applied to a real case of the {sup 238}U 6.674 eV resonant effective broadened absorption cross-section in UF6 (uranium hexafluoride). A direct experimental validation of our models is still necessary for which a special high resolution neutron transmission experiment ought to be devised at low temperatures and pressures on a gaseous system. It is showed how the synthetic model can be used to make thermometric predictions in an improved fashion in comparison to the effective temperature gas model at low temperatures.

  2. Integrated approach to assess ecosystem health in harbor areas.

    Science.gov (United States)

    Bebianno, M J; Pereira, C G; Rey, F; Cravo, A; Duarte, D; D'Errico, G; Regoli, F

    2015-05-01

    Harbors are critical environments with strategic economic importance but with potential environmental impact: health assessment criteria are a key issue. An ecosystem health status approach was carried out in Portimão harbor as a case-study. Priority and specific chemical levels in sediments along with their bioavailability in mussels, bioassays and a wide array of biomarkers were integrated in a biomarker index (IBR index) and the overall data in a weight of evidence (WOE) model. Metals, PAHs, PCBs and HCB were not particularly high compared with sediment guidelines and standards for dredging. Bioavailability was evident for Cd, Cu and Zn. Biomarkers proved more sensitive namely changes of antioxidant responses, metallothioneins and vittellogenin-like proteins. IBR index indicated that site 4 was the most impacted area. Assessment of the health status by WOE approach highlighted the importance of integrating sediment chemistry, bioaccumulation, biomarkers and bioassays and revealed that despite some disturbance in the harbor area, there was also an impact of urban effluents from upstream. Environmental quality assessment in harbors. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. Comparative analysis of magnetic resonance in the polaron pair recombination and the triplet exciton-polaron quenching models

    Science.gov (United States)

    Mkhitaryan, V. V.; Danilović, D.; Hippola, C.; Raikh, M. E.; Shinar, J.

    2018-01-01

    We present a comparative theoretical study of magnetic resonance within the polaron pair recombination (PPR) and the triplet exciton-polaron quenching (TPQ) models. Both models have been invoked to interpret the photoluminescence detected magnetic resonance (PLDMR) results in π -conjugated materials and devices. We show that resonance line shapes calculated within the two models differ dramatically in several regards. First, in the PPR model, the line shape exhibits unusual behavior upon increasing the microwave power: it evolves from fully positive at weak power to fully negative at strong power. In contrast, in the TPQ model, the PLDMR is completely positive, showing a monotonic saturation. Second, the two models predict different dependencies of the resonance signal on the photoexcitation power, PL. At low PL, the resonance amplitude Δ I /I is ∝PL within the PPR model, while it is ∝PL2 crossing over to PL3 within the TPQ model. On the physical level, the differences stem from different underlying spin dynamics. Most prominently, a negative resonance within the PPR model has its origin in the microwave-induced spin-Dicke effect, leading to the resonant quenching of photoluminescence. The spin-Dicke effect results from the spin-selective recombination, leading to a highly correlated precession of the on-resonance pair partners under the strong microwave power. This effect is not relevant for TPQ mechanism, where the strong zero-field splitting renders the majority of triplets off resonance. On the technical level, the analytical evaluation of the line shapes for the two models is enabled by the fact that these shapes can be expressed via the eigenvalues of a complex Hamiltonian. This bypasses the necessity of solving the much larger complex linear system of the stochastic Liouville equations. Our findings pave the way towards a reliable discrimination between the two mechanisms via cw PLDMR.

  4. Circuit model optimization of a nano split ring resonator dimer antenna operating in infrared spectral range

    International Nuclear Information System (INIS)

    Gneiding, N.; Zhuromskyy, O.; Peschel, U.; Shamonina, E.

    2014-01-01

    Metamaterials are comprised of metallic structures with a strong response to incident electromagnetic radiation, like, for example, split ring resonators. The interaction of resonator ensembles with electromagnetic waves can be simulated with finite difference or finite elements algorithms, however, above a certain ensemble size simulations become inadmissibly time or memory consuming. Alternatively a circuit description of metamaterials, a well developed modelling tool at radio and microwave frequencies, allows to significantly increase the simulated ensemble size. This approach can be extended to the IR spectral range with an appropriate set of circuit element parameters accounting for physical effects such as electron inertia and finite conductivity. The model is verified by comparing the coupling coefficients with the ones obtained from the full wave numerical simulations, and used to optimize the nano-antenna design with improved radiation characteristics.

  5. Absorption of acoustic waves by sunspots. II - Resonance absorption in axisymmetric fibril models

    Science.gov (United States)

    Rosenthal, C. S.

    1992-01-01

    Analytical calculations of acoustic waves scattered by sunspots which concentrate on the absorption at the magnetohydrodynamic Alfven resonance are extended to the case of a flux-tube embedded in a uniform atmosphere. The model is based on a flux-tubes of varying radius that are highly structured, translationally invariant, and axisymmetric. The absorbed fractional energy is determined for different flux-densities and subphotospheric locations with attention given to the effects of twist. When the flux is highly concentrated into annuli efficient absorption is possible even when the mean magnetic flux density is low. The model demonstrates low absorption at low azimuthal orders even in the presence of twist which generally increases the range of wave numbers over which efficient absorption can occur. Resonance absorption is concluded to be an efficient mechanism in monolithic sunspots, fibril sunspots, and plage fields.

  6. Multipole giant resonances of 12C nucleus electro excitation in intermediate coupling model

    International Nuclear Information System (INIS)

    Goncharova, N.G.; Zhivopistsev, F.A.

    1977-01-01

    Multipole giant resonances in 12 C electroexcitation are considered using the shell model with coupling. Cross sections are calculated for the states of 1 - , 2 - , 3 - , 4 - , at T=1. The distributions of the transverse form factor at transferred momenta equal to q approximately 0.75, 1.04, 1.22 and 1.56 Fm -1 and the longitudinal form factor for q = 0.75, 1.04, 1.56 Fm -1 are presented. For the excitation energies in the range from 18 to 28 MeV positive-parity states have a small contribution in the cross section. The distribution of the total form factor in the excitation energies is given. It is concluded that the multipole giant resonances of anomalous parity levels calculated within the interatomic-coupling shell model show a satisfactorily close agreement with the behavior of experimental form factors in the excitation energy range from 18 to 28 MeV

  7. Histopathologic correlation of magnetic resonance imaging signal patterns in a spinal cord injury model.

    Science.gov (United States)

    Weirich, S D; Cotler, H B; Narayana, P A; Hazle, J D; Jackson, E F; Coupe, K J; McDonald, C L; Langford, L A; Harris, J H

    1990-07-01

    Magnetic resonance imaging (MRI) provides a noninvasive method of monitoring the pathologic response to spinal cord injury. Specific MR signal intensity patterns appear to correlate with degrees of improvement in the neurologic status in spinal cord injury patients. Histologic correlation of two types of MR signal intensity patterns are confirmed in the current study using a rat animal model. Adult male Sprague-Dawley rats underwent spinal cord trauma at the midthoracic level using a weight-dropping technique. After laminectomy, 5- and 10-gm brass weights were dropped from designated heights onto a 0.1-gm impounder placed on the exposed dura. Animals allowed to regain consciousness demonstrated variable recovery of hind limb paraplegia. Magnetic resonance images were obtained from 2 hours to 1 week after injury using a 2-tesla MRI/spectrometer. Sacrifice under anesthesia was performed by perfusive fixation; spinal columns were excised en bloc, embedded, sectioned, and observed with the compound light microscope. Magnetic resonance axial images obtained during the time sequence after injury demonstrate a distinct correlation between MR signal intensity patterns and the histologic appearance of the spinal cord. Magnetic resonance imaging delineates the pathologic processes resulting from acute spinal cord injury and can be used to differentiate the type of injury and prognosis.

  8. Shear resonance mode decoupling to determine the characteristic matrix of piezoceramics for 3-D modeling.

    Science.gov (United States)

    Pardo, Lorena; García, Alvaro; de Espinosa, Francisco Montero; Brebøl, Klaus

    2011-03-01

    The determination of the characteristic frequencies of an electromechanical resonance does not provide enough data to obtain the material properties of piezoceramics, including all losses, from complex impedance measurements. Values of impedance around resonance and antiresonance frequencies are also required to calculate the material losses. Uncoupled resonances are needed for this purpose. The shear plates used for the material characterization present unavoidable mode coupling of the shear mode and other modes of the plate. A study of the evolution of the complex material coefficients as the coupling of modes evolves with the change in the aspect ratio (lateral dimension/thickness) of the plate is presented here. These are obtained using software. A soft commercial PZT ceramic was used in this study and several shear plates amenable to material characterization were obtained in the range of aspect ratios below 15. The validity of the material properties for 3-D modeling of piezoceramics is assessed by means of finite element analysis, which shows that uncoupled resonances are virtually pure thickness-driven shear modes.

  9. Modified model of neutron resonance widths distribution. Results of total gamma-widths approximation

    International Nuclear Information System (INIS)

    Sukhovoj, A.M.; Khitrov, V.A.

    2011-01-01

    Functional dependences of probability to observe given Γ n 0 value and algorithms for determination of the most probable magnitudes of the modified model of resonance parameter distributions were used for analysis of the experimental data on the total radiative widths of neutron resonances. As in the case of neutron widths, precise description of the Γ γ spectra requires a superposition of three and more probability distributions for squares of the random normally distributed values with different nonzero average and nonunit dispersion. This result confirms the preliminary conclusion obtained earlier at analysis of Γ n 0 that practically in all 56 tested sets of total gamma widths there are several groups noticeably differing from each other by the structure of their wave functions. In addition, it was determined that radiative widths are much more sensitive than the neutron ones to resonance wave functions structure. Analysis of early obtained neutron reduced widths distribution parameters for 157 resonance sets in the mass region of nuclei 35 ≤ A ≤ 249 was also performed. It was shown that the experimental values of widths can correspond with high probability to superposition of several expected independent distributions with their nonzero mean values and nonunit dispersion

  10. The interpretation of resonance formation in coupled-channel models of positron scattering by atomic hydrogen using localized optical potentials

    International Nuclear Information System (INIS)

    Bransden, B.H.; Hewitt, R.N.

    1997-01-01

    Above-threshold resonances can occur in coupled-channel models of the e + + H system when Ps formation is taken into account (although it should be pointed out that, in this specific system, resonances do not occur in an exact theory). In general, to understand the mechanism of resonance formation it is useful to obtain the exact optical potential in a given channel in a localized form. The methods of achieving this localization are discussed with reference to a specific application to the resonance found in the two-state approximation for the l = 0 partial wave. (author)

  11. Tsunami Induced Resonance in Enclosed Basins; Case Study of Haydarpasa Port In Istanbul

    Science.gov (United States)

    Kian, Rozita; Cevdet Yalciner, Ahmet; Zaytsev, Andrey; Aytore, Betul

    2015-04-01

    Coincidence of the frequency of forcing mechanisms and the natural frequency of free oscillations in the harbors or basins leads to formation of resonance oscillations and additional amplifications in the basins. This phenomenon becomes much more critical when it is caused by a tsunamis. In the cases of tsunami induced basin resonances, the wave amplifications may occur with more and unexpected damages. The harbor resilience against the marine hazards is important for the performance and success of recovery operations. Classifying the tsunami effects on the ports and harbors and on their functions is the main concern of this study. There are two types of impacts; direct impacts including structural damages due to strong currents, high water elevation and indirect ones because of basin resonance expose to seiche oscillations. The sea of Marmara has experienced numerous (more than 30) tsunamis in history where a highly populated metropolitan city Istanbul is located at North coast of Maramara sea. There are numerous ports and harbors located at Istanbul Coast. Haydarpasa port (41.0033 N, 29.0139 E) in Istanbul coast near Marmara sea, as a case study is selected to test its resilience under tsunami attack by numerical experiments. There are two breakwaters in Haydarpasa port with total length of three kilometers and the shape of basins are regular. Applying numerical model (NAMI DANCE) which solves nonlinear form of shallow water equations, the resonance oscillations in Haydarpasa Port is investigated by following the method given in Yalciner and Pelinovsky, (2006). In the applications, high resolution bathymetry and topography are used and an initial impulse is inputted to the study domain in the simulations. The computed time histories of water surface fluctuations at different locations inside the harbor are analyzed by using Fast Fourier Transform technique. The frequencies where the peaks of spectrum curves indicates the amplification of waves in the respective

  12. Stochastic resonance induced by novel random transitions of motion of FitzHugh-Nagumo neuron model

    International Nuclear Information System (INIS)

    Zhang Guangjun; Xu Jianxue

    2005-01-01

    In contrast to the previous studies which have dealt with stochastic resonance induced by random transitions of system motion between two coexisting limit cycle attractors in the FitzHugh-Nagumo (FHN) neuron model after Hopf bifurcation and which have dealt with the phenomenon of stochastic resonance induced by external noise when the model with periodic input has only one attractor before Hopf bifurcation, in this paper we have focused our attention on stochastic resonance (SR) induced by a novel transition behavior, the transitions of motion of the model among one attractor on the left side of bifurcation point and two attractors on the right side of bifurcation point under the perturbation of noise. The results of research show: since one bifurcation of transition from one to two limit cycle attractors and the other bifurcation of transition from two to one limit cycle attractors occur in turn besides Hopf bifurcation, the novel transitions of motion of the model occur when bifurcation parameter is perturbed by weak internal noise; the bifurcation point of the model may stochastically slightly shift to the left or right when FHN neuron model is perturbed by external Gaussian distributed white noise, and then the novel transitions of system motion also occur under the perturbation of external noise; the novel transitions could induce SR alone, and when the novel transitions of motion of the model and the traditional transitions between two coexisting limit cycle attractors after bifurcation occur in the same process the SR also may occur with complicated behaviors types; the mechanism of SR induced by external noise when FHN neuron model with periodic input has only one attractor before Hopf bifurcation is related to this kind of novel transition mentioned above

  13. Modeling and control of Type-2 wind turbines for sub-synchronous resonance damping

    International Nuclear Information System (INIS)

    Mancilla-David, Fernando; Domínguez-García, José Luis; De Prada, Mikel; Gomis-Bellmunt, Oriol; Singh, Mohit; Muljadi, Eduard

    2015-01-01

    Highlights: • Dynamic modeling of Type-2 wind turbines for sub-synchronous resonance studies. • Systematic design of a power system stabilizer for Type-2 wind turbines. • Assessment of Type-2 wind turbines to suppress sub-synchronous resonance events. - Abstract: The rapid increase of wind power penetration into power systems around the world has led transmission system operators to enforce stringent grid codes requiring novel functionalities from renewable energy-based power generation. For this reason, there exists a need to asses whether wind turbines (WTs) will comply with such functionalities to ensure power system stability. This paper demonstrates that Type-2 WTs may induce sub-synchronous resonance (SSR) events when connected to a series-compensated transmission line, and with proper control, they may also suppress such events. The paper presents a complete dynamic model tailored to study, via eigenanalysis, SSR events in the presence of Type-2 WTs, and a systematic procedure to design a power system stabilizer using only local and measurable signals. Results are validated through a case study based on the IEEE first benchmark model for SSR studies, as well as with transient computer simulations

  14. A Weakly Nonlinear Model for the Damping of Resonantly Forced Density Waves in Dense Planetary Rings

    Science.gov (United States)

    Lehmann, Marius; Schmidt, Jürgen; Salo, Heikki

    2016-10-01

    In this paper, we address the stability of resonantly forced density waves in dense planetary rings. Goldreich & Tremaine have already argued that density waves might be unstable, depending on the relationship between the ring’s viscosity and the surface mass density. In the recent paper Schmidt et al., we have pointed out that when—within a fluid description of the ring dynamics—the criterion for viscous overstability is satisfied, forced spiral density waves become unstable as well. In this case, linear theory fails to describe the damping, but nonlinearity of the underlying equations guarantees a finite amplitude and eventually a damping of the wave. We apply the multiple scale formalism to derive a weakly nonlinear damping relation from a hydrodynamical model. This relation describes the resonant excitation and nonlinear viscous damping of spiral density waves in a vertically integrated fluid disk with density dependent transport coefficients. The model consistently predicts density waves to be (linearly) unstable in a ring region where the conditions for viscous overstability are met. Sufficiently far away from the Lindblad resonance, the surface mass density perturbation is predicted to saturate to a constant value due to nonlinear viscous damping. The wave’s damping lengths of the model depend on certain input parameters, such as the distance to the threshold for viscous overstability in parameter space and the ground state surface mass density.

  15. Plasmonic Resonances for Spectroscopy Applications using 3D Finite-Difference Time-Domain Models

    Science.gov (United States)

    Ravi, Aruna

    Tuning plasmonic extinction resonances of sub-wavelength scale structures is essential to achieve maximum sensitivity and accuracy. These resonances can be controlled with careful design of nanoparticle geometries and incident wave attributes. In the first part of this dissertation, plasmonically enhanced effects on hexagonal-arrays of metal nanoparticles, metal-hole arrays (micro-mesh), and linear-arrays of metal nanorings are analyzed using three-dimensional Finite-Difference Time-Domain (3D-FDTD) simulations. The effect of particle size, lattice spacing, and lack of monodispersity of a self-assembled, hexagonal array layer of silver (Ag) nanoparticles on the extinction resonance is investigated to help determine optimal design specifications for efficient organic solar power harvesting. The enhancement of transmission resonances using plasmonic thin metal films with arrays of holes which enable recording of scatter-free infrared (IR) transmission spectra of individual particles is also explored. This method is quantitative, non-destructive and helps in better understanding the interaction of light with sub-wavelength particles. Next, plasmonically enhanced effects on linear arrays of gold (Au) rings are studied. Simulations employing 3D-FDTD can be used to determine the set of geometrical parameters to attain localized surface plasmon resonance (LSPR). The shifts in resonances due to changes in the effective dielectric of the structure are investigated, which is useful in sensing applications. Computational models enrich experimental studies. In the second part of this dissertation, the effect of particle size, shape and orientation on the IR spectra is investigated using 3D-FDTD and Mie-Bruggeman models. This computational analysis is extended to include clusters of particles of mixed composition. The prediction of extinction and absorption spectra of single particles of mixed composition helps in interpreting their physical properties and predict chemical

  16. Nonlinear dynamics of an electrically actuated imperfect microbeam resonator: Experimental investigation and reduced-order modeling

    KAUST Repository

    Ruzziconi, Laura

    2013-06-10

    We present a study of the dynamic behavior of a microelectromechanical systems (MEMS) device consisting of an imperfect clamped-clamped microbeam subjected to electrostatic and electrodynamic actuation. Our objective is to develop a theoretical analysis, which is able to describe and predict all the main relevant aspects of the experimental response. Extensive experimental investigation is conducted, where the main imperfections coming from microfabrication are detected, the first four experimental natural frequencies are identified and the nonlinear dynamics are explored at increasing values of electrodynamic excitation, in a neighborhood of the first symmetric resonance. Several backward and forward frequency sweeps are acquired. The nonlinear behavior is highlighted, which includes ranges of multistability, where the nonresonant and the resonant branch coexist, and intervals where superharmonic resonances are clearly visible. Numerical simulations are performed. Initially, two single mode reduced-order models are considered. One is generated via the Galerkin technique, and the other one via the combined use of the Ritz method and the Padé approximation. Both of them are able to provide a satisfactory agreement with the experimental data. This occurs not only at low values of electrodynamic excitation, but also at higher ones. Their computational efficiency is discussed in detail, since this is an essential aspect for systematic local and global simulations. Finally, the theoretical analysis is further improved and a two-degree-of-freedom reduced-order model is developed, which is also capable of capturing the measured second symmetric superharmonic resonance. Despite the apparent simplicity, it is shown that all the proposed reduced-order models are able to describe the experimental complex nonlinear dynamics of the device accurately and properly, which validates the proposed theoretical approach. © 2013 IOP Publishing Ltd.

  17. Kalman Filtered Bio Heat Transfer Model Based Self-adaptive Hybrid Magnetic Resonance Thermometry.

    Science.gov (United States)

    Zhang, Yuxin; Chen, Shuo; Deng, Kexin; Chen, Bingyao; Wei, Xing; Yang, Jiafei; Wang, Shi; Ying, Kui

    2017-01-01

    To develop a self-adaptive and fast thermometry method by combining the original hybrid magnetic resonance thermometry method and the bio heat transfer equation (BHTE) model. The proposed Kalman filtered Bio Heat Transfer Model Based Self-adaptive Hybrid Magnetic Resonance Thermometry, abbreviated as KalBHT hybrid method, introduced the BHTE model to synthesize a window on the regularization term of the hybrid algorithm, which leads to a self-adaptive regularization both spatially and temporally with change of temperature. Further, to decrease the sensitivity to accuracy of the BHTE model, Kalman filter is utilized to update the window at each iteration time. To investigate the effect of the proposed model, computer heating simulation, phantom microwave heating experiment and dynamic in-vivo model validation of liver and thoracic tumor were conducted in this study. The heating simulation indicates that the KalBHT hybrid algorithm achieves more accurate results without adjusting λ to a proper value in comparison to the hybrid algorithm. The results of the phantom heating experiment illustrate that the proposed model is able to follow temperature changes in the presence of motion and the temperature estimated also shows less noise in the background and surrounding the hot spot. The dynamic in-vivo model validation with heating simulation demonstrates that the proposed model has a higher convergence rate, more robustness to susceptibility problem surrounding the hot spot and more accuracy of temperature estimation. In the healthy liver experiment with heating simulation, the RMSE of the hot spot of the proposed model is reduced to about 50% compared to the RMSE of the original hybrid model and the convergence time becomes only about one fifth of the hybrid model. The proposed model is able to improve the accuracy of the original hybrid algorithm and accelerate the convergence rate of MR temperature estimation.

  18. Analytical Model for LLC Resonant Converter With Variable Duty-Cycle Control

    DEFF Research Database (Denmark)

    Shen, Yanfeng; Wang, Huai; Blaabjerg, Frede

    2016-01-01

    are identified and discussed. The proposed model enables a better understanding of the operation characteristics and fast parameter design of the LLC converter, which otherwise cannot be achieved by the existing simulation based methods and numerical models. The results obtained from the proposed model......In LLC resonant converters, the variable duty-cycle control is usually combined with a variable frequency control to widen the gain range, improve the light-load efficiency, or suppress the inrush current during start-up. However, a proper analytical model for the variable duty-cycle controlled LLC...... converter is still not available due to the complexity of operation modes and the nonlinearity of steady-state equations. This paper makes the efforts to develop an analytical model for the LLC converter with variable duty-cycle control. All possible operation models and critical operation characteristics...

  19. A Linearized Large Signal Model of an LCL-Type Resonant Converter

    Directory of Open Access Journals (Sweden)

    Hong-Yu Li

    2015-03-01

    Full Text Available In this work, an LCL-type resonant dc/dc converter with a capacitive output filter is modeled in two stages. In the first high-frequency ac stage, all ac signals are decomposed into two orthogonal vectors in a synchronous rotating d–q frame using multi-frequency modeling. In the dc stage, all dc quantities are represented by their average values with average state-space modeling. A nonlinear two-stage model is then created by means of a non-linear link. By aligning the transformer voltage on the d-axis, the nonlinear link can be eliminated, and the whole converter can be modeled by a single set of linear state-space equations. Furthermore, a feedback control scheme can be formed according to the steady-state solutions. Simulation and experimental results have proven that the resulted model is good for fast simulation and state variable estimation.

  20. Multi-axis force sensing using a resonant composite piezoelectric plate: model and experiments

    Science.gov (United States)

    Castaño-Cano, Davinson; Grossard, Mathieu; Hubert, Arnaud

    2015-05-01

    Wrist force/torque sensors used in robotic applications increase the performances and flexibility of the automated tasks. They also offer new possibilities in the manufacturing process, where physical contact between the work-piece and environment is required. The wide spreading of these sensors is for now restricted by their features. As an alternative to the existing strain-gauges force sensors, this paper presents a resonant composite structure, which is sensitive to multiple components of force that are considered via the pre-stress effect. Structurally bonded piezoelectric patches are used to bring the structure to its resonance, which is shifted according to applied forces. The relationship between force and frequency shift is modelled considering the multi-physics of this smart structure. This model is built using Hamilton's principle and takes into account pre-stress phenomena. A finite element model (FEM) based on Mindlin theory for plates, has been derived from the analytical model. The FEM model is implemented in MATLAB and compared with commercial FE software. Finally, an experimental prototype validates the model, and shows that it is possible to measure multiple force-components with one single sensing element such as a plate.

  1. Understanding disease processes in multiple sclerosis through magnetic resonance imaging studies in animal models

    Directory of Open Access Journals (Sweden)

    Nabeela Nathoo

    2014-01-01

    Full Text Available There are exciting new advances in multiple sclerosis (MS resulting in a growing understanding of both the complexity of the disorder and the relative involvement of grey matter, white matter and inflammation. Increasing need for preclinical imaging is anticipated, as animal models provide insights into the pathophysiology of the disease. Magnetic resonance (MR is the key imaging tool used to diagnose and to monitor disease progression in MS, and thus will be a cornerstone for future research. Although gadolinium-enhancing and T2 lesions on MRI have been useful for detecting MS pathology, they are not correlative of disability. Therefore, new MRI methods are needed. Such methods require validation in animal models. The increasing necessity for MRI of animal models makes it critical and timely to understand what research has been conducted in this area and what potential there is for use of MRI in preclinical models of MS. Here, we provide a review of MRI and magnetic resonance spectroscopy (MRS studies that have been carried out in animal models of MS that focus on pathology. We compare the MRI phenotypes of animals and patients and provide advice on how best to use animal MR studies to increase our understanding of the linkages between MR and pathology in patients. This review describes how MRI studies of animal models have been, and will continue to be, used in the ongoing effort to understand MS.

  2. Multi-axis force sensing using a resonant composite piezoelectric plate: model and experiments

    International Nuclear Information System (INIS)

    Castaño-Cano, Davinson; Grossard, Mathieu; Hubert, Arnaud

    2015-01-01

    Wrist force/torque sensors used in robotic applications increase the performances and flexibility of the automated tasks. They also offer new possibilities in the manufacturing process, where physical contact between the work-piece and environment is required. The wide spreading of these sensors is for now restricted by their features. As an alternative to the existing strain-gauges force sensors, this paper presents a resonant composite structure, which is sensitive to multiple components of force that are considered via the pre-stress effect. Structurally bonded piezoelectric patches are used to bring the structure to its resonance, which is shifted according to applied forces. The relationship between force and frequency shift is modelled considering the multi-physics of this smart structure. This model is built using Hamilton's principle and takes into account pre-stress phenomena. A finite element model (FEM) based on Mindlin theory for plates, has been derived from the analytical model. The FEM model is implemented in MATLAB and compared with commercial FE software. Finally, an experimental prototype validates the model, and shows that it is possible to measure multiple force-components with one single sensing element such as a plate. (paper)

  3. Improved magnetic resonance fingerprinting reconstruction with low-rank and subspace modeling.

    Science.gov (United States)

    Zhao, Bo; Setsompop, Kawin; Adalsteinsson, Elfar; Gagoski, Borjan; Ye, Huihui; Ma, Dan; Jiang, Yun; Ellen Grant, P; Griswold, Mark A; Wald, Lawrence L

    2018-02-01

    This article introduces a constrained imaging method based on low-rank and subspace modeling to improve the accuracy and speed of MR fingerprinting (MRF). A new model-based imaging method is developed for MRF to reconstruct high-quality time-series images and accurate tissue parameter maps (e.g., T 1 , T 2 , and spin density maps). Specifically, the proposed method exploits low-rank approximations of MRF time-series images, and further enforces temporal subspace constraints to capture magnetization dynamics. This allows the time-series image reconstruction problem to be formulated as a simple linear least-squares problem, which enables efficient computation. After image reconstruction, tissue parameter maps are estimated via dictionary-based pattern matching, as in the conventional approach. The effectiveness of the proposed method was evaluated with in vivo experiments. Compared with the conventional MRF reconstruction, the proposed method reconstructs time-series images with significantly reduced aliasing artifacts and noise contamination. Although the conventional approach exhibits some robustness to these corruptions, the improved time-series image reconstruction in turn provides more accurate tissue parameter maps. The improvement is pronounced especially when the acquisition time becomes short. The proposed method significantly improves the accuracy of MRF, and also reduces data acquisition time. Magn Reson Med 79:933-942, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  4. Modelling of magneto-acoustic resonance in ferrite-piezoelectric bilayers

    Energy Technology Data Exchange (ETDEWEB)

    Bichurin, M I; Petrov, V M; Averkin, S V; Filippov, A V [Institute for Electronic Information Systems, Novgorod State University, Veliky Novgorod 173003 (Russian Federation); Liverts, E [Department of Physics, Ben-Gurion University of the Negev, Beersheva 84105 (Israel); Mandal, S; Srinivasan, G [Physics Department, Oakland University, Rochester, MI 48309 (United States)

    2009-11-07

    A model is discussed for magnetoelectric (ME) effects in a single-crystal ferrite-piezoelectric bilayer on a substrate. The specific focus is on coupling at magneto-acoustic resonance (MAR) at the coincidence of ferromagnetic resonance in the ferrite and thickness modes of the electromechanical resonance in the piezoelectric. The clamping effect of the substrate has been considered in determining the ME voltage coefficient and applied to a model system of a bilayer of lead zirconate titanate (PZT) and yttrium iron garnet (YIG) on a gadolinium gallium garnet substrate. The theory predicts a giant ME effect at MAR due to interaction and transfer of energy between elastic modes and the uniform precession spin-wave mode. It is shown that the ME coupling strength decreases with increasing substrate thickness. Estimates for YIG-PZT for nominal film parameters predict MAR at 5 GHz and ME coefficients on the order of 5-70 V cm{sup -1} Oe{sup -1}. The phenomenon is of importance for the realization of multifunctional ME sensors and transducers operating at microwave frequencies.

  5. A Novel Murine Model for Localized Radiation Necrosis and its Characterization Using Advanced Magnetic Resonance Imaging

    International Nuclear Information System (INIS)

    Jost, Sarah C.; Hope, Andrew; Kiehl, Erich; Perry, Arie; Travers, Sarah; Garbow, Joel R.

    2009-01-01

    Purpose: To develop a murine model of radiation necrosis using fractionated, subtotal cranial irradiation; and to investigate the imaging signature of radiation-induced tissue damage using advanced magnetic resonance imaging techniques. Methods and Materials: Twenty-four mice each received 60 Gy of hemispheric (left) irradiation in 10 equal fractions. Magnetic resonance images at 4.7 T were subsequently collected using T1-, T2-, and diffusion sequences at selected time points after irradiation. After imaging, animals were killed and their brains fixed for correlative histologic analysis. Results: Contrast-enhanced T1- and T2-weighted magnetic resonance images at months 2, 3, and 4 showed changes consistent with progressive radiation necrosis. Quantitatively, mean diffusivity was significantly higher (mean = 0.86, 1.13, and 1.24 μm 2 /ms at 2, 3, and 4 months, respectively) in radiated brain, compared with contralateral untreated brain tissue (mean = 0.78, 0.82, and 0.83 μm 2 /ms) (p < 0.0001). Histology reflected changes typically seen in radiation necrosis. Conclusions: This murine model of radiation necrosis will facilitate investigation of imaging biomarkers that distinguish between radiation necrosis and tumor recurrence. In addition, this preclinical study supports clinical data suggesting that diffusion-weighted imaging may be helpful in answering this diagnostic question in clinical settings.

  6. Multi-dimensional Inversion Modeling of Surface Nuclear Magnetic Resonance (SNMR Data for Groundwater Exploration

    Directory of Open Access Journals (Sweden)

    Warsa

    2014-07-01

    Full Text Available Groundwater is an important economic source of water supply for drinking water and irrigation water for agriculture. Surface nuclear magnetic resonance (SNMR sounding is a relatively new geophysical method that can be used to determine the presence of culturally and economically important substances, such as subsurface water or hydrocarbon distribution. SNMR sounding allows the determination of water content and pore size distribution directly from the surface. The SNMR method is performed by stimulating an alternating current pulse through an antenna at the surface in order to confirm the existence of water in the subsurface. This paper reports the development of a 3-D forward modeling code for SNMR amplitudes and decay times, after which an improved 2-D and 3-D inversion algorithm is investigated, consisting of schemes for regularizing model parameterization. After briefly reviewing inversion schemes generally used in geophysics, the special properties of SNMR or magnetic resonance sounding (MRS inversion are evaluated. We present an extension of MRS to magnetic resonance tomography (MRT, i.e. an extension for 2-D and 3-D investigation, and the appropriate inversions.

  7. Genetics Home Reference: Floating-Harbor syndrome

    Science.gov (United States)

    ... Patton MA, Hurst J, Donnai D, McKeown CM, Cole T, Goodship J. Floating-Harbor syndrome. J Med ... medicine? What is newborn screening? New Pages Lyme disease Fibromyalgia White-Sutton syndrome All New & Updated Pages ...

  8. Extreme Wave-Induced Oscillation in Paradip Port Under the Resonance Conditions

    Science.gov (United States)

    Kumar, Prashant; Gulshan

    2017-12-01

    A mathematical model is constructed to analyze the long wave-induced oscillation in Paradip Port, Odisha, India under the resonance conditions to avert any extreme wave hazards. Boundary element method (BEM) with corner contribution is utilized to solve the Helmholtz equation under the partial reflection boundary conditions. Furthermore, convergence analysis is also performed for the boundary element scheme with uniform and non-uniform discretization of the boundary. The numerical scheme is also validated with analytic approximation and existing studies based on harbor resonance. Then, the amplification factor is estimated at six key record stations in the Paradip Port with multidirectional incident waves and resonance modes are also estimated at the boundary of the port. Ocean surface wave field is predicted in the interior of Paradip Port for the different directional incident wave at various resonance modes. Moreover, the safe locations in the port have been identified for loading and unloading of moored ship with different resonance modes and directional incident waves.

  9. A numerical model of the mirror electron cyclotron resonance MECR source

    International Nuclear Information System (INIS)

    Hellblom, G.

    1986-03-01

    Results from numerical modeling of a new type of ion source are presented. The plasma in this source is produced by electron cyclotron resonance in a strong conversion magnetic field. Experiments have shown that a well-defined plasma column, extended along the magnetic field (z-axis) can be produced. The electron temperature and the densities of the various plasma particles have been found to have a strong z-position dependence. With the numerical model, a simulation of the evolution of the composition of the plasma as a function of z is made. A qualitative agreement with experimental data can be obtained for certain parameter regimes. (author)

  10. The optical/ultraviolet excess of isolated neutron stars in the resonant cyclotron scattering model

    Science.gov (United States)

    Tong, Hao; Xu, Ren-Xin; Song, Li-Ming

    2011-12-01

    X-ray dim isolated neutron stars are peculiar pulsar-like objects, characterized by their Planck-like spectrum. In studying their spectral energy distributions, optical/ultraviolet (UV) excess is a long standing problem. Recently Kaplan et al. measured the optical/UV excess for all seven sources, which is understandable in the resonant cyclotron scattering (RCS) model previously addressed. The RCS model calculations show that the RCS process can account for the observed optical/UV excess for most sources. The flat spectrum of RX J2143.0+0654 may be due to contributions from the bremsstrahlung emission of the electron system in addition to the RCS process.

  11. Combined electromagnetic and photoreaction modeling of CLD-1 photobleaching in polymer microring resonators

    Science.gov (United States)

    Huang, Yanyi; Poon, Joyce K. S.; Liang, Wei; Yariv, Amnon; Zhang, Cheng; Dalton, Larry R.

    2005-08-01

    By combining a solid-state photoreaction model with the modal solutions of an optical waveguide, we simulate the refractive index change due to the photobleaching of CLD-1 chromophores in an amorphous polycarbonate microring resonator. The simulation agrees well with experimental results. The photobleaching quantum efficiency of the CLD-1 chromophores is determined to be 0.65%. The combined modeling of the electromagnetic wave propagation and photoreaction precisely illustrates the spatial and temporal evolution of the optical properties of the polymer material as manifested in the refractive index and their effects on the modal and physical properties of the optical devices.

  12. Motor circuit computer model based on studies of functional Nuclear Magnetic Resonance

    International Nuclear Information System (INIS)

    Garcia Ramo, Karla Batista; Rodriguez Rojas, Rafael; Carballo Barreda, Maylen

    2012-01-01

    The basal ganglia are a complex network of subcortical nuclei involved in motor control, sensorimotor integration, and cognitive processes. Their functioning and interaction with other cerebral structures remains as a subject of debate. The aim of the present work was to simulate the basal ganglia-thalamus-cortex circuitry interaction in motor program selection, supported by functional connectivity pattern obtained by functional nuclear magnetic resonance imaging. Determination of connections weights between neural populations by functional magnetic resonance imaging, contributed to a more realistic formulation of the model; and consequently to obtain similar results to clinical and experimental data. The network allowed to describe the participation of the basal ganglia in motor program selection and the changes in Parkinson disease. The simulation allowed to demonstrate that dopamine depletion above to 40 % leads to a loss of action selection capability, and to reflect the system adaptation ability to compensate dysfunction in Parkinson disease, coincident with experimental and clinical studies

  13. Investigation of the resonant power oscillation in the Halden Boiling Water Reactor by autoregressive modeling

    International Nuclear Information System (INIS)

    Oguma, Ritsuo

    1980-01-01

    In the HBWR (Halden Boiling Water Reactor), there exists a resonant power oscillation with period about 0.04 Hz at power levels higher than about 9.5 MWt. While the resonant oscillation in not so large as to affect the normal reactor operation, it is significant, from the viewpoint of reactor diagnosis, to grasp its characteristics and find the cause. Noise analysis based on the autoregressive (AR) modeling technique has been made to reveal the driving source for this oscillation which led to the suggestion that it is attributed to the dynamic interference of heat exchange process between two parallel-connected steam transformers against the reactor. The present study demonstrates that the method used here is highly effective for tracing back to a noise source inducing the variation of quantities in a system, and also applicable to problems of reactor noise analysis and diagnosis. (author)

  14. Fluctuations induced extinction and stochastic resonance effect in a model of tumor growth with periodic treatment

    Energy Technology Data Exchange (ETDEWEB)

    Li Dongxi, E-mail: lidongxi@mail.nwpu.edu.c [Department of Applied Mathematics, Northwestern Polytechnical University, Xi' an 710072 (China); Xu Wei; Guo, Yongfeng; Xu Yong [Department of Applied Mathematics, Northwestern Polytechnical University, Xi' an 710072 (China)

    2011-01-31

    We investigate a stochastic model of tumor growth derived from the catalytic Michaelis-Menten reaction with positional and environmental fluctuations under subthreshold periodic treatment. Firstly, the influences of environmental fluctuations on the treatable stage are analyzed numerically. Applying the standard theory of stochastic resonance derived from the two-state approach, we derive the signal-to-noise ratio (SNR) analytically, which is used to measure the stochastic resonance phenomenon. It is found that the weak environmental fluctuations could induce the extinction of tumor cells in the subthreshold periodic treatment. The positional stability is better in favor of the treatment of the tumor cells. Besides, the appropriate and feasible treatment intensity and the treatment cycle should be highlighted considered in the treatment of tumor cells.

  15. Fluctuations induced extinction and stochastic resonance effect in a model of tumor growth with periodic treatment

    International Nuclear Information System (INIS)

    Li Dongxi; Xu Wei; Guo, Yongfeng; Xu Yong

    2011-01-01

    We investigate a stochastic model of tumor growth derived from the catalytic Michaelis-Menten reaction with positional and environmental fluctuations under subthreshold periodic treatment. Firstly, the influences of environmental fluctuations on the treatable stage are analyzed numerically. Applying the standard theory of stochastic resonance derived from the two-state approach, we derive the signal-to-noise ratio (SNR) analytically, which is used to measure the stochastic resonance phenomenon. It is found that the weak environmental fluctuations could induce the extinction of tumor cells in the subthreshold periodic treatment. The positional stability is better in favor of the treatment of the tumor cells. Besides, the appropriate and feasible treatment intensity and the treatment cycle should be highlighted considered in the treatment of tumor cells.

  16. Madaket Harbor, Nantucket, Massachusetts. Water Resources Improvement.

    Science.gov (United States)

    1977-07-01

    will continue to be, important increases in the recreational use of land and water. The harbor area is an important arena for commercial shellfishing...an important arena for commercial shell fishing. The past few years have seen a rather rapid increase in residential land use. Construction has...beamc. Tnis material will be re-deposited,, viaj troio it 1-apfro1inr ox prior location. j, MADAKET HARBOR NANTUCKET, MASSACHUSETTS FEASIBILITY

  17. Methodologies for Wind Turbine and STATCOM Integration in Wind Power Plant Models for Harmonic Resonances Assessment

    DEFF Research Database (Denmark)

    Freijedo Fernandez, Francisco Daniel; Chaudhary, Sanjay Kumar; Guerrero, Josep M.

    2015-01-01

    -domain. As an alternative, a power based averaged modelling is also proposed. Type IV wind turbine harmonic signature and STATCOM active harmonic mitigation are considered for the simulation case studies. Simulation results provide a good insight of the features and limitations of the proposed methodologies.......This paper approaches modelling methodologies for integration of wind turbines and STATCOM in harmonic resonance studies. Firstly, an admittance equivalent model representing the harmonic signature of grid connected voltage source converters is provided. A simplified type IV wind turbine modelling...... is then straightforward. This linear modelling is suitable to represent the wind turbine in the range of frequencies at which harmonic interactions are likely. Even the admittance method is suitable both for frequency and time domain studies, some limitations arise in practice when implementing it in the time...

  18. Damping width of giant dipole resonances of cold and hot nuclei: A macroscopic model

    International Nuclear Information System (INIS)

    Mughabghab, S.F.; Sonzogni, A.A.

    2002-01-01

    A phenomenological macroscopic model of the giant dipole resonance (GDR) damping width of cold and hot nuclei with ground-state spherical and near-spherical shapes is developed. The model is based on a generalized Fermi liquid model which takes into account the nuclear surface dynamics. The temperature dependence of the GDR damping width is accounted for in terms of surface and volume components. Parameter-free expressions for the damping width and the effective deformation are obtained. The model is validated with GDR measurements of the following nuclides: 39,40 K, 42 Ca, 45 Sc, 59,63 Cu, 109-120 Sn, 147 Eu, 194 Hg, and 208 Pb, and is compared with the predictions of other models

  19. Recent Advances in Translational Magnetic Resonance Imaging in Animal Models of Stress and Depression.

    Science.gov (United States)

    McIntosh, Allison L; Gormley, Shane; Tozzi, Leonardo; Frodl, Thomas; Harkin, Andrew

    2017-01-01

    Magnetic resonance imaging (MRI) is a valuable translational tool that can be used to investigate alterations in brain structure and function in both patients and animal models of disease. Regional changes in brain structure, functional connectivity, and metabolite concentrations have been reported in depressed patients, giving insight into the networks and brain regions involved, however preclinical models are less well characterized. The development of more effective treatments depends upon animal models that best translate to the human condition and animal models may be exploited to assess the molecular and cellular alterations that accompany neuroimaging changes. Recent advances in preclinical imaging have facilitated significant developments within the field, particularly relating to high resolution structural imaging and resting-state functional imaging which are emerging techniques in clinical research. This review aims to bring together the current literature on preclinical neuroimaging in animal models of stress and depression, highlighting promising avenues of research toward understanding the pathological basis of this hugely prevalent disorder.

  20. Do basal Ganglia amplify willed action by stochastic resonance? A model.

    Directory of Open Access Journals (Sweden)

    V Srinivasa Chakravarthy

    Full Text Available Basal ganglia are usually attributed a role in facilitating willed action, which is found to be impaired in Parkinson's disease, a pathology of basal ganglia. We hypothesize that basal ganglia possess the machinery to amplify will signals, presumably weak, by stochastic resonance. Recently we proposed a computational model of Parkinsonian reaching, in which the contributions from basal ganglia aid the motor cortex in learning to reach. The model was cast in reinforcement learning framework. We now show that the above basal ganglia computational model has all the ingredients of stochastic resonance process. In the proposed computational model, we consider the problem of moving an arm from a rest position to a target position: the two positions correspond to two extrema of the value function. A single kick (a half-wave of sinusoid, of sufficiently low amplitude given to the system in resting position, succeeds in taking the system to the target position, with high probability, only at a critical noise level. But for suboptimal noise levels, the model arm's movements resemble Parkinsonian movement symptoms like akinetic rigidity (low noise and dyskinesias (high noise.

  1. On the synthesis of resonance lines in dynamical models of structured hot-star winds

    Science.gov (United States)

    Puls, J.; Owocki, S. P.; Fullerton, A. W.

    1993-01-01

    We examine basic issues involved in synthesizing resonance-line profiles from 1-D, dynamical models of highly structured hot-star winds. Although these models exhibit extensive variations in density as well as velocity, the density scale length is still typically much greater than the Sobolev length. The line transfer is thus treated using a Sobolev approach, as generalized by Rybicki & Hummer (1978) to take proper account of the multiple Sobolev resonances arising from the nonmonotonic velocity field. The resulting reduced-lambda-matrix equation describing nonlocal coupling of the source function is solved by iteration, and line profiles are then derived from formal solution integration using this source function. Two more approximate methods that instead use either a stationary or a structured, local source function yield qualitatively similar line-profiles, but are found to violate photon conservation by 10% or more. The full results suggest that such models may indeed be able to reproduce naturally some of the qualitative properties long noted in observed UV line profiles, such as discrete absorption components in unsaturated lines, or the blue-edge variability in saturated lines. However, these particular models do not yet produce the black absorption troughs commonly observed in saturated lines, and it seems that this and other important discrepancies (e.g., in acceleration time scale of absorption components) may require development of more complete models that include rotation and other 2-D and/or 3-D effects.

  2. The Higgs boson resonance from a chiral Higgs-Yukawa model on the lattice

    Energy Technology Data Exchange (ETDEWEB)

    Kallarackal, Jim

    2011-04-28

    Despite the fact that the standard model of particle physics has been confirmed in many high energy experiments, the existence of the Higgs boson is not assured. The Higgs boson is a central part of the electroweak theory and is crucial to generate masses for fermions and the weak gauge bosons. The goal of this work is to set limits on the mass and the decay width of the Higgs boson. The basis to compute the physical quantities is the path integral which is here evaluated by means of Monte Carlo simulations thus allowing for fully non perturbative calculations. A polynomial hybrid Monte Carlo algorithm is used to incorporate dynamical fermions. The chiral symmetry of the electroweak model is incorporated by using the Neuberger overlap operator. Here, the standard model is considered in the limit of a Higgs-Yukawa sector which does not contain the weak gauge bosons and only a degenerate doublet of top- and bottom quarks are incorporated. Results from lattice perturbation theory up to one loop of the Higgs boson propagator are compared with those obtained from Monte Carlo simulations at three different values of the Yukawa coupling. At all values of the investigated couplings, the perturbative results agree very well with the Monte Carlo data. A main focus of this work is the investigation of the resonance parameters of the Higgs boson. The resonance width and the resonance mass are investigated at weak and at large quartic couplings. The parameters of the model are chosen such that the Higgs boson can decay into any even number of Goldstone bosons. Thus, the Higgs boson does not appear as an asymptotic stable state but as a resonance. In all considered cases the Higgs boson resonance width lies below 10% of the resonance mass. The obtained resonance mass is compared with the mass obtained from the Higgs boson propagator. The results agree perfectly at all values of the quartic coupling considered. Finally, the effect of a heavy fourth generation of fermions on the

  3. The Higgs boson resonance from a chiral Higgs-Yukawa model on the lattice

    International Nuclear Information System (INIS)

    Kallarackal, Jim

    2011-01-01

    Despite the fact that the standard model of particle physics has been confirmed in many high energy experiments, the existence of the Higgs boson is not assured. The Higgs boson is a central part of the electroweak theory and is crucial to generate masses for fermions and the weak gauge bosons. The goal of this work is to set limits on the mass and the decay width of the Higgs boson. The basis to compute the physical quantities is the path integral which is here evaluated by means of Monte Carlo simulations thus allowing for fully non perturbative calculations. A polynomial hybrid Monte Carlo algorithm is used to incorporate dynamical fermions. The chiral symmetry of the electroweak model is incorporated by using the Neuberger overlap operator. Here, the standard model is considered in the limit of a Higgs-Yukawa sector which does not contain the weak gauge bosons and only a degenerate doublet of top- and bottom quarks are incorporated. Results from lattice perturbation theory up to one loop of the Higgs boson propagator are compared with those obtained from Monte Carlo simulations at three different values of the Yukawa coupling. At all values of the investigated couplings, the perturbative results agree very well with the Monte Carlo data. A main focus of this work is the investigation of the resonance parameters of the Higgs boson. The resonance width and the resonance mass are investigated at weak and at large quartic couplings. The parameters of the model are chosen such that the Higgs boson can decay into any even number of Goldstone bosons. Thus, the Higgs boson does not appear as an asymptotic stable state but as a resonance. In all considered cases the Higgs boson resonance width lies below 10% of the resonance mass. The obtained resonance mass is compared with the mass obtained from the Higgs boson propagator. The results agree perfectly at all values of the quartic coupling considered. Finally, the effect of a heavy fourth generation of fermions on the

  4. Acoustic radiation force induced resonance elastography of coagulating blood: theoretical viscoelasticity modeling and ex vivo experimentation

    Science.gov (United States)

    Bhatt, Manish; Montagnon, Emmanuel; Destrempes, François; Chayer, Boris; Kazemirad, Siavash; Cloutier, Guy

    2018-03-01

    Deep vein thrombosis is a common vascular disease that can lead to pulmonary embolism and death. The early diagnosis and clot age staging are important parameters for reliable therapy planning. This article presents an acoustic radiation force induced resonance elastography method for the viscoelastic characterization of clotting blood. The physical concept of this method relies on the mechanical resonance of the blood clot occurring at specific frequencies. Resonances are induced by focusing ultrasound beams inside the sample under investigation. Coupled to an analytical model of wave scattering, the ability of the proposed method to characterize the viscoelasticity of a mimicked venous thrombosis in the acute phase is demonstrated. Experiments with a gelatin-agar inclusion sample of known viscoelasticity are performed for validation and establishment of the proof of concept. In addition, an inversion method is applied in vitro for the kinetic monitoring of the blood coagulation process of six human blood samples obtained from two volunteers. The computed elasticity and viscosity values of blood samples at the end of the 90 min kinetics were estimated at 411  ±  71 Pa and 0.25  ±  0.03 Pa · s for volunteer #1, and 387  ±  35 Pa and 0.23  ±  0.02 Pa · s for volunteer #2, respectively. The proposed method allowed reproducible time-varying thrombus viscoelastic measurements from samples having physiological dimensions.

  5. Simultaneous multislice magnetic resonance fingerprinting with low-rank and subspace modeling.

    Science.gov (United States)

    Bo Zhao; Bilgic, Berkin; Adalsteinsson, Elfar; Griswold, Mark A; Wald, Lawrence L; Setsompop, Kawin

    2017-07-01

    Magnetic resonance fingerprinting (MRF) is a new quantitative imaging paradigm that enables simultaneous acquisition of multiple magnetic resonance tissue parameters (e.g., T 1 , T 2 , and spin density). Recently, MRF has been integrated with simultaneous multislice (SMS) acquisitions to enable volumetric imaging with faster scan time. In this paper, we present a new image reconstruction method based on low-rank and subspace modeling for improved SMS-MRF. Here the low-rank model exploits strong spatiotemporal correlation among contrast-weighted images, while the subspace model captures the temporal evolution of magnetization dynamics. With the proposed model, the image reconstruction problem is formulated as a convex optimization problem, for which we develop an algorithm based on variable splitting and the alternating direction method of multipliers. The performance of the proposed method has been evaluated by numerical experiments, and the results demonstrate that the proposed method leads to improved accuracy over the conventional approach. Practically, the proposed method has a potential to allow for a 3× speedup with minimal reconstruction error, resulting in less than 5 sec imaging time per slice.

  6. A Squeeze-film Damping Model for the Circular Torsion Micro-resonators

    Science.gov (United States)

    Yang, Fan; Li, Pu

    2017-07-01

    In recent years, MEMS devices are widely used in many industries. The prediction of squeeze-film damping is very important for the research of high quality factor resonators. In the past, there have been many analytical models predicting the squeeze-film damping of the torsion micro-resonators. However, for the circular torsion micro-plate, the works over it is very rare. The only model presented by Xia et al[7] using the method of eigenfunction expansions. In this paper, The Bessel series solution is used to solve the Reynolds equation under the assumption of the incompressible gas of the gap, the pressure distribution of the gas between two micro-plates is obtained. Then the analytical expression for the damping constant of the device is derived. The result of the present model matches very well with the finite element method (FEM) solutions and the result of Xia’s model, so the present models’ accuracy is able to be validated.

  7. Spallation Neutron Source Drift Tube Linac Resonance Control Cooling System Modeling

    CERN Document Server

    Tang, Johnny Y; Champion, Marianne M; Feschenko, Alexander; Gibson, Paul; Kiselev, Yuri; Kovalishin, A S; Kravchuk, Leonid V; Kvasha, Adolf; Schubert, James P

    2005-01-01

    The Resonance Control Cooling System (RCCS) for the warm linac of the Spallation Neutron Source was designed by Los Alamos National Laboratory. The primary design focus was on water cooling of individual component contributions. The sizing the RCCS water skid was accomplished by means of a specially created SINDA/FLUINT model tailored to these system requirements. A new model was developed in Matlab Simulink and incorporates actual operational values and control valve interactions. Included is the dependence of RF input power on system operation, cavity detuning values during transients, time delays that result from water flows through the heat exchanger, the dynamic process of water warm-up in the cooling system due to dissipated RF power on the cavity surface, differing contributions on the cavity detuning due to drift tube and wall heating, and a dynamic model of the heat exchanger with characteristics in close agreement to the real unit. Because of the Matlab Simulink model, investigation of a wide range ...

  8. Multi-component fiber track modelling of diffusion-weighted magnetic resonance imaging data

    Directory of Open Access Journals (Sweden)

    Yasser M. Kadah

    2010-01-01

    Full Text Available In conventional diffusion tensor imaging (DTI based on magnetic resonance data, each voxel is assumed to contain a single component having diffusion properties that can be fully represented by a single tensor. Even though this assumption can be valid in some cases, the general case involves the mixing of components, resulting in significant deviation from the single tensor model. Hence, a strategy that allows the decomposition of data based on a mixture model has the potential of enhancing the diagnostic value of DTI. This project aims to work towards the development and experimental verification of a robust method for solving the problem of multi-component modelling of diffusion tensor imaging data. The new method demonstrates significant error reduction from the single-component model while maintaining practicality for clinical applications, obtaining more accurate Fiber tracking results.

  9. Absolute cross sections from the ''boomerang model'' for resonant electron-molecule scattering

    International Nuclear Information System (INIS)

    Dube, L.; Herzenberg, A.

    1979-01-01

    The boomerang model is used to calculate absolute cross sections near the 2 Pi/sub g/ shape resonance in e-N 2 scattering. The calculated cross sections are shown to satisfy detailed balancing. The exchange of electrons is taken into account. A parametrized complex-potential curve for the intermediate N 2 /sup ts-/ ion is determined from a small part of the experimental data, and then used to calculate other properties. The calculations are in good agreement with the absolute cross sections for vibrational excitation from the ground state, the absolute cross section v = 1 → 2, and the absolute total cross section

  10. Estimation of parasitic losses in a proposed mesoscale resonant engine: Experiment and model

    Science.gov (United States)

    Preetham, B. S.; Anderson, M.; Richards, C.

    2014-02-01

    A resonant engine in which the piston-cylinder assembly is replaced by a flexible cavity is realized at the mesoscale using flexible metal bellows to demonstrate the feasibility of the concept. A four stroke motoring technique is developed and measurements are performed to determine parasitic losses. A non-linear lumped parameter model is developed to evaluate the engine performance. Experimentally, the heat transfer and friction effects are separated by varying the engine speed and operating frequency. The engine energy flow diagram showing the energy distribution among various parasitic elements reveals that the friction loss in the bellows is smaller than the sliding friction loss in a typical piston-cylinder assembly.

  11. Multichannel coupling with supersymmetric quantum mechanics and exactly-solvable model for the Feshbach resonance

    International Nuclear Information System (INIS)

    Sparenberg, Jean-Marc; Samsonov, Boris F; Foucart, Francois; Baye, Daniel

    2006-01-01

    A new type of supersymmetric transformations of the coupled-channel radial Schroedinger equation is introduced, which do not conserve the vanishing behaviour of solutions at the origin. Contrary to the usual transformations, these 'non-conservative' transformations allow, in the presence of thresholds, the construction of well-behaved potentials with coupled scattering matrices from uncoupled potentials. As an example, an exactly-solvable potential matrix is obtained which provides a very simple model of the Feshbach-resonance phenomenon. (letter to the editor)

  12. The Hagedorn Spectrum and the Dual Resonance Model: An Old Love Affair

    CERN Document Server

    Veneziano, Gabriele

    2016-01-01

    In this contribution I recall how people working in the late 1960s on the dual resonance model came to the surprising discovery of a Hagedorn-like spectrum, and why they should not have been surprised. I will then turn to discussing the Hagedorn spectrum from a string theory viewpoint (which adds a huge degeneracy to the exponential spectrum). Finally, I will discuss how all this can be reinterpreted in the new incarnation of string theory through the properties of quantum black holes.

  13. Resonant spin-flavor conversion of supernova neutrinos: Dependence on presupernova models and future prospects

    Science.gov (United States)

    Ando, Shin'ichiro; Sato, Katsuhiko

    2003-07-01

    We study the resonant spin-flavor (RSF) conversion of supernova neutrinos, which is induced by the interaction between the nonzero neutrino magnetic moment and the supernova magnetic fields, and its dependence on presupernova models. As the presupernova models, we adopt the latest ones by Woosley, Heger, and Weaver, and, further, models with both solar and zero metallicity are investigated. Since the (1-2Ye) profile of the new presupernova models, which is responsible for the RSF conversion, suddenly drops at the resonance region, the completely adiabatic RSF conversion is not realized, even if μνB0=(10-12μB)(1010 G), where B0 is the strength of the magnetic field at the surface of the iron core. In particular for the model with zero metallicity, the conversion is highly nonadiabatic in the high energy region, reflecting the (1-2Ye) profile of the model. In calculating the flavor conversion, we find that the shock wave propagation, which changes density profiles drastically, is a much more severe problem than it is for the pure Mikheyev-Smirnov-Wolfenstein (MSW) conversion case. This is because the RSF effect occurs at a far deeper region than the MSW effect. To avoid the uncertainty concerning the shock propagation, we restrict our discussion to 0.5 s after the core bounce (and for more conservative discussion, 0.25 s), during which the shock wave is not expected to affect the RSF region. We also evaluate the energy spectrum at the Super-Kamiokande detector for various models using the calculated conversion probabilities, and find that it is very difficult to obtain useful information on the supernova metallicities and magnetic fields or on the neutrino magnetic moment from the supernova neutrino observation. Future prospects are also discussed.

  14. SAR in human head model due to resonant wireless power transfer system.

    Science.gov (United States)

    Zhang, Chao; Liu, Guoqiang; Li, Yanhong; Song, Xianjin

    2016-04-29

    Efficient mid-range wireless power transfer between transmitter and the receiver has been achieved based on the magnetic resonant coupling method. The influence of electromagnetic field on the human body due to resonant wireless power transfer system (RWPT) should be taken into account during the design process of the system. To analyze the transfer performance of the RWPT system and the change rules of the specific absorption rate (SAR) in the human head model due to the RWPT system. The circuit-field coupling method for a RWPT system with consideration of the displacement current was presented. The relationship between the spiral coil parameters and transfer performance was studied. The SAR in the human head model was calculated under two different exposure conditions. A system with output power higher than 10 W at 0.2 m distance operating at a frequency of approximately 1 MHz was designed. The FEM simulation results show the peak SAR value is below the safety limit which appeared when the human head model is in front of the transmitter. The simulation results agreed well with the experimental results, which verified the validity of the analysis and design.

  15. Non-linear magnetohydrodynamic modeling of plasma response to resonant magnetic perturbations

    Energy Technology Data Exchange (ETDEWEB)

    Orain, F.; Bécoulet, M.; Dif-Pradalier, G.; Nardon, E.; Passeron, C.; Latu, G.; Grandgirard, V.; Fil, A.; Ratnani, A. [CEA, IRFM, F-13108 Saint-Paul-Lez-Durance (France); Huijsmans, G. [ITER Organization, Route de Vinon, F-13115 Saint-Paul-Lez-Durance (France); Pamela, S. [IIFS-PIIM. Aix Marseille Université - CNRS, 13397 Marseille Cedex20 (France); Chapman, I.; Kirk, A.; Thornton, A. [EURATOM/CCFE Fusion Association, Culham Science Centre, Oxon OX14 3DB (United Kingdom); Hoelzl, M. [Max-Planck-Institut für Plasmaphysik, EURATOM Association, Garching (Germany); Cahyna, P. [Association EURATOM/IPP.CR, Prague (Czech Republic)

    2013-10-15

    The interaction of static Resonant Magnetic Perturbations (RMPs) with the plasma flows is modeled in toroidal geometry, using the non-linear resistive MHD code JOREK, which includes the X-point and the scrape-off-layer. Two-fluid diamagnetic effects, the neoclassical poloidal friction and a source of toroidal rotation are introduced in the model to describe realistic plasma flows. RMP penetration is studied taking self-consistently into account the effects of these flows and the radial electric field evolution. JET-like, MAST, and ITER parameters are used in modeling. For JET-like parameters, three regimes of plasma response are found depending on the plasma resistivity and the diamagnetic rotation: at high resistivity and slow rotation, the islands generated by the RMPs at the edge resonant surfaces rotate in the ion diamagnetic direction and their size oscillates. At faster rotation, the generated islands are static and are more screened by the plasma. An intermediate regime with static islands which slightly oscillate is found at lower resistivity. In ITER simulations, the RMPs generate static islands, which forms an ergodic layer at the very edge (ψ≥0.96) characterized by lobe structures near the X-point and results in a small strike point splitting on the divertor targets. In MAST Double Null Divertor geometry, lobes are also found near the X-point and the 3D-deformation of the density and temperature profiles is observed.

  16. Protein structure analysis using the resonant recognition model and wavelet transforms

    International Nuclear Information System (INIS)

    Fang, Q.; Cosic, I.

    1998-01-01

    An approach based on the resonant recognition model and the discrete wavelet transform is introduced here for characterising proteins' biological function. The protein sequence is converted into a numerical series by assigning the electron-ion interaction potential to each amino acid from N-terminal to C-terminal. A set of peaks is found after performing a wavelet transform onto a numerical series representing a group of homologous proteins. These peaks are related to protein structural and functional properties and named characteristic vector of that protein group. Further more, the amino acids contributing mostly to a protein's biological functions, the so-called 'hot spots' amino acids, are predicted by the continuous wavelet transform. It is found that the hot spots are clustered around the protein's cleft structure. The wavelets approach provides a novel methods for amino acid sequence analysis as well as an expansion for the newly established macromolecular interaction model: the resonant recognition model. Copyright (1998) Australasian Physical and Engineering Sciences in Medicine

  17. 76 FR 8653 - Drawbridge Operation Regulation; Gulf Intracoastal Waterway, New Orleans Harbor, Inner Harbor...

    Science.gov (United States)

    2011-02-15

    ... Operation Regulation; Gulf Intracoastal Waterway, New Orleans Harbor, Inner Harbor Navigation Canal, New Orleans, Orleans Parish, LA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from... Lock), at New Orleans, Orleans Parish, Louisiana. This deviation is necessary to replace all of the...

  18. 75 FR 78601 - Drawbridge Operation Regulation; Gulf Intracoastal Waterway, New Orleans Harbor, Inner Harbor...

    Science.gov (United States)

    2010-12-16

    ... Operation Regulation; Gulf Intracoastal Waterway, New Orleans Harbor, Inner Harbor Navigation Canal, New Orleans, Orleans Parish, LA AGENCY: Coast Guard, DHS. ACTION: Notice of temporary deviation from... Harvey Lock), at New Orleans, Orleans Parish, Louisiana. This deviation is necessary to adjust the...

  19. High-Resolution Longitudinal Screening with Magnetic Resonance Imaging in a Murine Brain Cancer Model

    Directory of Open Access Journals (Sweden)

    Nicholas A. Bock

    2003-11-01

    Full Text Available One of the main limitations of intracranial models of diseases is our present inability to monitor and evaluate the intracranial compartment noninvasively over time. Therefore, there is a growing need for imaging modalities that provide thorough neuropathological evaluations of xenograft and transgenic models of intracranial pathology. In this study, we have established protocols for multiple-mouse magnetic resonance imaging (MRI to follow the growth and behavior of intracranial xenografts of gliomas longitudinally. We successfully obtained weekly images on 16 mice for a total of 5 weeks on a 7-T multiple-mouse MRI. T2- and Ti-weighted imaging with gadolinium enhancement of vascularity was used to detect tumor margins, tumor size, and growth. These experiments, using 3D whole brain images obtained in four mice at once, demonstrate the feasibility of obtaining repeat radiological images in intracranial tumor models and suggest that MRI should be incorporated as a research modality for the investigation of intracranial pathobiology.

  20. Neural Model for Left-Handed CPW Bandpass Filter Loaded Split Ring Resonator

    Science.gov (United States)

    Liu, Haiwen; Wang, Shuxin; Tan, Mingtao; Zhang, Qijun

    2010-02-01

    Compact left-handed coplanar waveguide (CPW) bandpass filter loaded split ring resonator (SRR) is presented in this paper. The proposed filter exhibits a quasi-elliptic function response and its circuit size occupies only 12 × 11.8 mm2 (≈0.21 λg × 0.20 λg). Also, a simple circuit model is given and the parametric study of this filter is discussed. Then, with the aid of NeuroModeler software, a five-layer feed-forward perceptron neural networks model is built up to optimize the proposed filter design fast and accurately. Finally, this newly left-handed CPW bandpass filter was fabricated and measured. A good agreement between simulations and measurement verifies the proposed left-handed filter and the validity of design methodology.

  1. A model of electrostatically actuated MEMS and carbon nanotubes resonators for biological mass detection

    KAUST Repository

    Bouchaala, Adam M.

    2015-01-01

    We investigate the dynamics of electrically actuated Micro and Nano (Carbon nanotube (CNT)) cantilever beams implemented as resonant sensors for mass detection of biological elements. The beams are modeled using an Euler-Bernoulli beam theory including the nonlinear electrostatic forces and the added biological elements, which are modeled as a discrete point mass. A multi-mode Galerkin procedure is utilized to derive a reduced-order model, which is used for the dynamic simulations. The frequency shifts due to added mass of Escherichia coli (E. coli) and Prostate Specific Antigen (PSA) are calculated for the primary and higher order modes of vibrations. Also, analytical expressions of the natural frequency shift under dc voltage and added mass have been developed. We found that using higher-order modes of vibration of MEMS beams or miniaturizing the size of the beam to Nano scale leads to significant improved sensitivity. © Springer International Publishing Switzerland 2015.

  2. The Higgs boson resonance width from a chiral Higgs-Yukawa model on the lattice

    International Nuclear Information System (INIS)

    Gerhold, Philipp; Kallarackal, Jim; Humboldt-Universitaet, Berlin; Jansen, Karl

    2011-11-01

    The Higgs boson is a central part of the electroweak theory and is crucial to generate masses for quarks, leptons and the weak gauge bosons. We use a 4-dimensional Euclidean lattice formulation of the Higgs-Yukawa sector of the electroweak model to compute physical quantities in the path integral approach which is evaluated by means of Monte Carlo simulations thus allowing for fully non perturbative calculations. The chiral symmetry of the model is incorporated by using the Neuberger overlap Dirac operator. The here considered Higgs-Yukawa model does not involve the weak gauge bosons and furthermore, only a degenerate doublet of top- and bottom quarks are incorporated. The goal of this work is to study the resonance properties of the Higgs boson and its sensitivity to the strength of the quartic self coupling. (orig.)

  3. Nonlinear Modeling and Simulation of Thermal Effects in Microcantilever Resonators Dynamic

    International Nuclear Information System (INIS)

    Tadayon, M A; Sayyaadi, H; Jazar, G Nakhaie

    2006-01-01

    Thermal dependency of material characteristics in micro electromechanical systems strongly affects their performance, design, and control. Hence, it is essential to understand and model that in MEMS devices to optimize their designs. A thermal phenomenon introduces two main effects: damping due to internal friction, and softening due to Young modulus temperature relation. Based on some reported theoretical and experimental results, we model the thermal phenomena and use two Lorentzian functions to describe the restoring and damping forces caused by thermal phenomena. In order to emphasize the thermal effects, a nonlinear model of the MEMS, by considering capacitor nonlinearity, have been used. The response of the system is developed by employing multiple time scales perturbation method on nondimensionalized form of equations. Frequency response, resonant frequency and peak amplitude are examined for variation of dynamic parameters involved

  4. 3D Modeling of Vascular Pathologies from contrast enhanced magnetic resonance images (MRI)

    International Nuclear Information System (INIS)

    Cantor Rivera, Diego; Orkisz, Maciej; Arias, Julian; Uriza, Luis Felipe

    2007-01-01

    This paper presents a method for generating 3D vascular models from contrast enhanced magnetic resonance images (MRI) using a fast marching algorithm. The main contributions of this work are: the use of the original image for defining a speed function (which determines the movement of the interface) and the calculation of the time in which the interface identifies the artery. The proposed method was validated on pathologic carotid artery images of patients and vascular phantoms. A visual appraisal of vascular models obtained with the method shows a satisfactory extraction of the vascular wall. A quantitative assessment proved that the generated models depend on the values of algorithm parameters. The maximum induced error was equal to 1.34 voxels in the diameter of the measured stenoses.

  5. Application of the resonating Hartree-Fock random phase approximation to the Lipkin model

    International Nuclear Information System (INIS)

    Nishiyama, S.; Ishida, K.; Ido, M.

    1996-01-01

    We have applied the resonating Hartree-Fock (Res-HF) approximation to the exactly solvable Lipkin model by utilizing a newly developed orbital-optimization algorithm. The Res-HF wave function was superposed by two Slater determinants (S-dets) which give two corresponding local energy minima of monopole ''deformations''. The self-consistent Res-HF calculation gives an excellent ground-state correlation energy. There exist excitations due to small vibrational fluctuations of the orbitals and mixing coefficients around their stationary values. They are described by a new approximation called the resonating Hartree-Fock random phase approximation (Res-HF RPA). Matrices of the second-order variation of the Res-HF energy have the same structures as those of the Res-HF RPA's matrices. The quadratic steepest descent of the Res-HF energy in the orbital optimization is considered to include certainly both effects of RPA-type fluctuations up to higher orders and their mode-mode couplings. It is a very important and interesting task to apply the Res-HF RPA to the Lipkin model with the use of the stationary values and to prove the above argument. It turns out that the Res-HF RPA works far better than the usual HF RPA and the renormalized one. We also show some important features of the Res-HF RPA. (orig.)

  6. Preclinical Magnetic Resonance Fingerprinting (MRF) at 7 T: Effective Quantitative Imaging for Rodent Disease Models

    Science.gov (United States)

    Gao, Ying; Chen, Yong; Ma, Dan; Jiang, Yun; Herrmann, Kelsey A.; Vincent, Jason A.; Dell, Katherine M.; Drumm, Mitchell L.; Brady-Kalnay, Susann M.; Griswold, Mark A.; Flask, Chris A.; Lu, Lan

    2015-01-01

    High field, preclinical magnetic resonance imaging (MRI) scanners are now commonly used to quantitatively assess disease status and efficacy of novel therapies in a wide variety of rodent models. Unfortunately, conventional MRI methods are highly susceptible to respiratory and cardiac motion artifacts resulting in potentially inaccurate and misleading data. We have developed an initial preclinical, 7.0 T MRI implementation of the highly novel Magnetic Resonance Fingerprinting (MRF) methodology that has been previously described for clinical imaging applications. The MRF technology combines a priori variation in the MRI acquisition parameters with dictionary-based matching of acquired signal evolution profiles to simultaneously generate quantitative maps of T1 and T2 relaxation times and proton density. This preclinical MRF acquisition was constructed from a Fast Imaging with Steady-state Free Precession (FISP) MRI pulse sequence to acquire 600 MRF images with both evolving T1 and T2 weighting in approximately 30 minutes. This initial high field preclinical MRF investigation demonstrated reproducible and differentiated estimates of in vitro phantoms with different relaxation times. In vivo preclinical MRF results in mouse kidneys and brain tumor models demonstrated an inherent resistance to respiratory motion artifacts as well as sensitivity to known pathology. These results suggest that MRF methodology may offer the opportunity for quantification of numerous MRI parameters for a wide variety of preclinical imaging applications. PMID:25639694

  7. Modeling the neutron spin-flip process in a time-of-flight spin-resonance energy filter

    CERN Document Server

    Parizzi, A A; Klose, F

    2002-01-01

    A computer program for modeling the neutron spin-flip process in a novel time-of-flight (TOF) spin-resonance energy filter has been developed. The software allows studying the applicability of the device in various areas of spallation neutron scattering instrumentation, for example as a dynamic TOF monochromator. The program uses a quantum-mechanical approach to calculate the local spin-dependent spectra and is essential for optimizing the magnetic field profiles along the resonator axis. (orig.)

  8. The description of neutron and giant resonances within the quasiparticle-phonon nuclear model

    International Nuclear Information System (INIS)

    Soloviev, V.G.

    1978-01-01

    The general assumptions of the quasiparticle-phonon model of complex nuclei are given. The choice of the model Hamiltonian as an average field and residual forces is discussed. The phonon description and quasiparticle-phonon interaction are presented. The system of basic equations and their approximate solutions are obtained. The approximation is chosen so as to obtain the most correct description of few-quasiparticle components rather than of the whole wave function. The method of strength functions is presented, which plays a decisive role in practical realization of the quasiparticle-phonon model for the description of some properties of complex nuclei. The range of applicability of the quasiparticle-phonon nuclear model is determined as few-quasiparticle components of the wave functions at low, intermediate and high excitation energies averaged in a certain energy interval. The fragmentation of single-particle states in deformed nuclei is studied within this model. The dependence of neutron strength functions on the excitation energy is investigated for the transfer reactions of the type (d,p) and (d,t). The s - ,p - , and d-wave neutron strength functions are calculated at the neutron binding energy Bsub(n). A satisfactory agreement with experiment is obtained. A correct description of the radiative strength functions in spherical nuclei is obtained. The influence of the tail of the giant dipole resonance on the E1-strength functions is studied. The energies and EΛ-strength functions for giant multipole resonances in spherical and deformed nuclei are calculated. A correct description of their widths is obtained. (author)

  9. New Harbor in Kangerlussuaq, Western Greenland

    DEFF Research Database (Denmark)

    Stenstad, Jaran Gjerlandj; Eppeland, Kjetil Grødal; Ingeman-Nielsen, Thomas

    2015-01-01

    transported by rivers from the inland ice to the inner parts of the fjord. These sediment layers reduce the water depth and prevent container- and cruiseships to dock, imposing large additional maintenance costs, and inefficient operability. Through engineering geological field and lab investigations......, a possible new harbor location around 10 km further out the fjord near Hancock Pynt, has been investigated. The onshore area was found to be highly suitable for a harbor support area, where a sub-base thickness of 1.8 m with gravel cover-layer was found adequate for the calculated design loads. Existing...

  10. The spectral energy distributions of isolated neutron stars in the resonant cyclotron scattering model

    Science.gov (United States)

    Tong, Hao; Xu, Renxin

    2013-03-01

    The X-ray dim isolated neutron stars (XDINSs) are peculiar pulsar-like objects, characterized by their very well Planck-like spectrum. In studying their spectral energy distributions, the optical/UV excess is a long standing problem. Recently, Kaplan et al. (2011) have measured the optical/UV excess for all seven sources, which is understandable in the resonant cyclotron scattering (RCS) model previously addressed. The RCS model calculations show that the RCS process can account for the observed optical/UV excess for most sources. The flat spectrum of RX J2143.0+0654 may due to contribution from bremsstrahlung emission of the electron system in addition to the RCS process.

  11. Memory effects on a resonate-and-fire neuron model subjected to Ornstein-Uhlenbeck noise

    Science.gov (United States)

    Paekivi, S.; Mankin, R.; Rekker, A.

    2017-10-01

    We consider a generalized Langevin equation with an exponentially decaying memory kernel as a model for the firing process of a resonate-and-fire neuron. The effect of temporally correlated random neuronal input is modeled as Ornstein-Uhlenbeck noise. In the noise-induced spiking regime of the neuron, we derive exact analytical formulas for the dependence of some statistical characteristics of the output spike train, such as the probability distribution of the interspike intervals (ISIs) and the survival probability, on the parameters of the input stimulus. Particularly, on the basis of these exact expressions, we have established sufficient conditions for the occurrence of memory-time-induced transitions between unimodal and multimodal structures of the ISI density and a critical damping coefficient which marks a dynamical transition in the behavior of the system.

  12. Channel noise enhances signal detectability in a model of acoustic neuron through the stochastic resonance paradigm.

    Science.gov (United States)

    Liberti, M; Paffi, A; Maggio, F; De Angelis, A; Apollonio, F; d'Inzeo, G

    2009-01-01

    A number of experimental investigations have evidenced the extraordinary sensitivity of neuronal cells to weak input stimulations, including electromagnetic (EM) fields. Moreover, it has been shown that biological noise, due to random channels gating, acts as a tuning factor in neuronal processing, according to the stochastic resonant (SR) paradigm. In this work the attention is focused on noise arising from the stochastic gating of ionic channels in a model of Ranvier node of acoustic fibers. The small number of channels gives rise to a high noise level, which is able to cause a spike train generation even in the absence of stimulations. A SR behavior has been observed in the model for the detection of sinusoidal signals at frequencies typical of the speech.

  13. Generalized Net Model of the Cognitive and Neural Algorithm for Adaptive Resonance Theory 1

    Directory of Open Access Journals (Sweden)

    Todor Petkov

    2013-12-01

    Full Text Available The artificial neural networks are inspired by biological properties of human and animal brains. One of the neural networks type is called ART [4]. The abbreviation of ART stands for Adaptive Resonance Theory that has been invented by Stephen Grossberg in 1976 [5]. ART represents a family of Neural Networks. It is a cognitive and neural theory that describes how the brain autonomously learns to categorize, recognize and predict objects and events in the changing world. In this paper we introduce a GN model that represent ART1 Neural Network learning algorithm [1]. The purpose of this model is to explain when the input vector will be clustered or rejected among all nodes by the network. It can also be used for explanation and optimization of ART1 learning algorithm.

  14. Bodily tides near the 1:1 spin-orbit resonance: correction to Goldreich's dynamical model

    Science.gov (United States)

    Williams, James G.; Efroimsky, Michael

    2012-12-01

    Spin-orbit coupling is often described in an approach known as " the MacDonald torque", which has long become the textbook standard due to its apparent simplicity. Within this method, a concise expression for the additional tidal potential, derived by MacDonald (Rev Geophys 2:467-541, 1994), is combined with a convenient assumption that the quality factor Q is frequency-independent (or, equivalently, that the geometric lag angle is constant in time). This makes the treatment unphysical because MacDonald's derivation of the said formula was, very implicitly, based on keeping the time lag frequency-independent, which is equivalent to setting Q scale as the inverse tidal frequency. This contradiction requires the entire MacDonald treatment of both non-resonant and resonant rotation to be rewritten. The non-resonant case was reconsidered by Efroimsky and Williams (Cel Mech Dyn Astron 104:257-289, 2009), in application to spin modes distant from the major commensurabilities. In the current paper, we continue this work by introducing the necessary alterations into the MacDonald-torque-based model of falling into a 1-to-1 resonance. (The original version of this model was offered by Goldreich (Astron J 71:1-7, 1996). Although the MacDonald torque, both in its original formulation and in its corrected version, is incompatible with realistic rheologies of minerals and mantles, it remains a useful toy model, which enables one to obtain, in some situations, qualitatively meaningful results without resorting to the more rigorous (and complicated) theory of Darwin and Kaula. We first address this simplified model in application to an oblate primary body, with tides raised on it by an orbiting zero-inclination secondary. (Here the role of the tidally-perturbed primary can be played by a satellite, the perturbing secondary being its host planet. A planet may as well be the perturbed primary, its host star acting as the tide-raising secondary). We then extend the model to a

  15. Quantum thermodynamics of the resonant-level model with driven system-bath coupling

    Science.gov (United States)

    Haughian, Patrick; Esposito, Massimiliano; Schmidt, Thomas L.

    2018-02-01

    We study nonequilibrium thermodynamics in a fermionic resonant-level model with arbitrary coupling strength to a fermionic bath, taking the wide-band limit. In contrast to previous theories, we consider a system where both the level energy and the coupling strength depend explicitly on time. We find that, even in this generalized model, consistent thermodynamic laws can be obtained, up to the second order in the drive speed, by splitting the coupling energy symmetrically between system and bath. We define observables for the system energy, work, heat, and entropy, and calculate them using nonequilibrium Green's functions. We find that the observables fulfill the laws of thermodynamics, and connect smoothly to the known equilibrium results.

  16. Science Court on ICRH [ion cyclotron resonance heating] modeling of tokamak plasmas

    International Nuclear Information System (INIS)

    Hively, L.M.; Sadowski, W.L.

    1987-10-01

    The Applied Plasma Physics (APP) Theory program in the Office of Fusion Energy is charged with supporting the development of advanced physics models for fusion research. One such effort is ion cyclotron resonance heating (ICRH), which has seen substantial progress recently. However, due to serious questions about the adequacy of present models for CIT (Compact Ignition Tokamak), a Science Court was formed to assess ICRH models, including: validity of theoretical and computational approximations; underlying physics assumptions and corresponding limits on the results; self-consistency; any subsidiary issues needing resolution (e.g., new computer tools); adequacy of the models in simulating experiments (especially CIT); and new or improved experiments to validate and refine the models. The Court did not review work by specific individuals, institutions, or programs, thereby avoiding any biases along these lines. Rather, the Science Court was carefully structured as a technical review of ICRH theory and modeling in the US. This paper discusses the Science Court process, findings, and conclusions

  17. Nonlinear Container Ship Model for the Study of Parametric Roll Resonance

    Directory of Open Access Journals (Sweden)

    Christian Holden

    2007-10-01

    Full Text Available Parametric roll is a critical phenomenon for ships, whose onset may cause roll oscillations up to +-40 degrees, leading to very dangerous situations and possibly capsizing. Container ships have been shown to be particularly prone to parametric roll resonance when they are sailing in moderate to heavy head seas. A Matlab/Simulink parametric roll benchmark model for a large container ship has been implemented and validated against a wide set of experimental data. The model is a part of a Matlab/Simulink Toolbox (MSS, 2007. The benchmark implements a 3rd-order nonlinear model where the dynamics of roll is strongly coupled with the heave and pitch dynamics. The implemented model has shown good accuracy in predicting the container ship motions, both in the vertical plane and in the transversal one. Parametric roll has been reproduced for all the data sets in which it happened, and the model provides realistic results which are in good agreement with the model tank experiments.

  18. Modelling of Plasma Response to Resonant Magnetic Perturbations and its Influence on Divertor Strike Points

    Energy Technology Data Exchange (ETDEWEB)

    Cahyna, P.; Peterka, M.; Panek, R., E-mail: cahyna@ipp.cas.cz [Institute of Plasma Physics AS CR, Prague (Czech Republic); Liu, Y.; Kirk, A.; Harrison, J.; Thornton, A.; Chapman, I. [EURATOM/CCFE Fusion Association, Culham Science Centre, Abingdon (United Kingdom); Nardon, E. [Association Euratom/CEA, CEA Cadarache, St. Paul-lez-Durance (France); Schmitz, O. [Forschung Zentrum Juelich, Juelich (Germany)

    2012-09-15

    Full text: Resonant magnetic perturbations (RMPs) for edge localized mode (ELM) mitigation in tokamaks can be modified by the plasma response and indeed strong screening of the applied perturbation is in some cases predicted by simulations. In this contribution we investigate what effect would such screening have on the spiralling patterns (footprints) which may appear at the divertor when RMPs are applied. We use two theoretical tools for investigation of the impact of plasma response on footprints: a simple model of the assumed screening currents, which can be used to translate the screening predicted by MHD codes in a simplified geometry into the real geometry, and the MHD code MARS-F. The former consistently predicts that footprints are significantly reduced when complete screening of the resonant perturbation modes (like it is the case in ideal MHD) is assumed. This result is supported by the result of MARS-F in ideal mode for the case of the MAST tokamak. To predict observed patterns of fluxes it is necessary to take into account the deformation of the scrape-off layer, and for this we developed an approximative method based on the Melnikov integral. If the screening of perturbations indeed reduces the footprints, it would provide us with an important tool to evaluate the amount of screening in experiments, as the footprints can be easily observed. We thus present a comparison between predictions and experimental data, especially for the MAST tokamak, where a significant amount of data has been collected. (author)

  19. Applications of Magnetic Resonance in Model Systems: Tumor Biology and Physiology

    Directory of Open Access Journals (Sweden)

    Robert J. Gillies

    2000-01-01

    Full Text Available A solid tumor presents a unique challenge as a system in which the dynamics of the relationship between vascularization, the physiological environment and metabolism are continually changing with growth and following treatment. Magnetic resonance imaging (MRI and magnetic resonance spectroscopy (MRS studies have demonstrated quantifiable linkages between the physiological environment, angiogenesis, vascularization and metabolism of tumors. The dynamics between these parameters continually change with tumor aggressiveness, tumor growth and during therapy and each of these can be monitored longitudinally, quantitatively and non-invasively with MRI and MRS. An important aspect of MRI and MRS studies is that techniques and findings are easily translated between systems. Hence, pre-clinical studies using cultured cells or experimental animals have a high connectivity to potential clinical utility. In the following review, leaders in the field of MR studies of basic tumor physiology using pre-clinical models have contributed individual sections according to their expertise and outlook. The following review is a cogent and timely overview of the current capabilities and state-of-the-art of MRI and MRS as applied to experimental cancers. A companion review deals with the application of MR methods to anticancer therapy.

  20. Higgs boson resonance parameters and the finite temperature phase transition in a chirally invariant Higgs-Yukawa model

    Energy Technology Data Exchange (ETDEWEB)

    Bulava, John; Jansen, Karl [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Gerhold, Philip; Kallarackal, Jim; Nagy, Attila [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Humbolt-Univ. Berlin (Germany)

    2011-12-15

    We study a chirally invariant Higgs-Yukawa model regulated on a space-time lattice. We calculate Higgs boson resonance parameters and mass bounds for various values of the mass of the degenerate fermion doublet. Also, first results on the phase transition temperature are presented. In general, this model may be relevant for BSM scenarios with a heavy fourth generation of quarks. (orig.)

  1. Evaluation of Sediment Contamination in Pearl Harbor

    Science.gov (United States)

    1992-06-01

    ancient Hawaiians, was a large natural inland lagoon. Numerous walled fishponds located inside the harbor were used to cultivate various species of fishes... Ecotoxicology , Commission on Natural Resources, National Academy Press, Washington, D.C., 103 pp. National Research Council, 1989. Contaminated Marine

  2. Precision tools and models to narrow in on the 750 GeV diphoton resonance

    International Nuclear Information System (INIS)

    Staub, Florian; Athron, Peter; Basso, Lorenzo

    2016-02-01

    The hints for a new resonance at 750 GeV from ATLAS and CMS have triggered a significant amount of attention. Since the simplest extensions of the standard model cannot accommodate the observation, many alternatives have been considered to explain the excess. Here we focus on several proposed renormalisable weakly-coupled models and revisit results given in the literature. We point out that physically important subtleties are often missed or neglected. To facilitate the study of the excess we have created a collection of 40 model files, selected from recent literature, for the Mathematica package SARAH. With SARAH one can generate files to perform numerical studies using the tailor-made spectrum generators FlexibleSUSY and SPheno. These have been extended to automatically include crucial higher order corrections to the diphoton and digluon decay rates for both CP-even and CP-odd scalars. Additionally, we have extended the UFO and CalcHep interfaces of SARAH, to pass the precise information about the effective vertices from the spectrum generator to a Monte-Carlo tool. Finally, as an example to demonstrate the power of the entire setup, we present a new supersymmetric model that accommodates the diphoton excess, explicitly demonstrating how a large width can be obtained. We explicitly show several steps in detail to elucidate the use of these public tools in the precision study of this model.

  3. A prediction model for the grade of liver fibrosis using magnetic resonance elastography.

    Science.gov (United States)

    Mitsuka, Yusuke; Midorikawa, Yutaka; Abe, Hayato; Matsumoto, Naoki; Moriyama, Mitsuhiko; Haradome, Hiroki; Sugitani, Masahiko; Tsuji, Shingo; Takayama, Tadatoshi

    2017-11-28

    Liver stiffness measurement (LSM) has recently become available for assessment of liver fibrosis. We aimed to develop a prediction model for liver fibrosis using clinical variables, including LSM. We performed a prospective study to compare liver fibrosis grade with fibrosis score. LSM was measured using magnetic resonance elastography in 184 patients that underwent liver resection, and liver fibrosis grade was diagnosed histologically after surgery. Using the prediction model established in the training group, we validated the classification accuracy in the independent test group. First, we determined a cut-off value for stratifying fibrosis grade using LSM in 122 patients in the training group, and correctly diagnosed fibrosis grades of 62 patients in the test group with a total accuracy of 69.3%. Next, on least absolute shrinkage and selection operator analysis in the training group, LSM (r = 0.687, P prediction model. This prediction model applied to the test group correctly diagnosed 32 of 36 (88.8%) Grade I (F0 and F1) patients, 13 of 18 (72.2%) Grade II (F2 and F3) patients, and 7 of 8 (87.5%) Grade III (F4) patients in the test group, with a total accuracy of 83.8%. The prediction model based on LSM, ICGR15, and platelet count can accurately and reproducibly predict liver fibrosis grade.

  4. Precision tools and models to narrow in on the 750 GeV diphoton resonance

    Energy Technology Data Exchange (ETDEWEB)

    Staub, Florian [CERN, Theoretical Physics Department, Geneva (Switzerland); Athron, Peter [Monash University, ARC Centre of Excellence for Particle Physics at the Terascale, School of Physics, Melbourne, VIC (Australia); Basso, Lorenzo [CPPM, Aix-Marseille Universite, CNRS-IN2P3, UMR 7346, Marseille Cedex 9 (France); Goodsell, Mark D. [Sorbonne Universites, LPTHE, UMR 7589, CNRS and Universite Pierre et Marie Curie, Paris Cedex 05 (France); Harries, Dylan [The University of Adelaide, Department of Physics, ARC Centre of Excellence for Particle Physics at the Terascale, Adelaide, SA (Australia); Krauss, Manuel E.; Nickel, Kilian; Opferkuch, Toby [Bethe Center for Theoretical Physics and Physikalisches Institut der Universitaet Bonn, Bonn (Germany); Ubaldi, Lorenzo [Tel-Aviv University, Raymond and Beverly Sackler School of Physics and Astronomy, Tel Aviv (Israel); Vicente, Avelino [Instituto de Fisica Corpuscular (CSIC-Universitat de Valencia), Valencia (Spain); Voigt, Alexander [Deutsches Elektronen-Synchrotron DESY, Hamburg (Germany)

    2016-09-15

    The hints for a new resonance at 750 GeV from ATLAS and CMS have triggered a significant amount of attention. Since the simplest extensions of the standard model cannot accommodate the observation, many alternatives have been considered to explain the excess. Here we focus on several proposed renormalisable weakly-coupled models and revisit results given in the literature. We point out that physically important subtleties are often missed or neglected. To facilitate the study of the excess we have created a collection of 40 model files, selected from recent literature, for the Mathematica package SARAH. With SARAH one can generate files to perform numerical studies using the tailor-made spectrum generators FlexibleSUSY and SPheno. These have been extended to automatically include crucial higher order corrections to the diphoton and digluon decay rates for both CP-even and CP-odd scalars. Additionally, we have extended the UFO and CalcHep interfaces of SARAH, to pass the precise information about the effective vertices from the spectrum generator to a Monte-Carlo tool. Finally, as an example to demonstrate the power of the entire setup, we present a new supersymmetric model that accommodates the diphoton excess, explicitly demonstrating how a large width can be obtained. We explicitly show several steps in detail to elucidate the use of these public tools in the precision study of this model. (orig.)

  5. Precision tools and models to narrow in on the 750 GeV diphoton resonance

    Energy Technology Data Exchange (ETDEWEB)

    Staub, Florian [CERN, Geneva (Switzerland). Theoretical Physics Dept.; Athron, Peter [Monash Univ., Melbourne (Australia). ARC Center of Excellence for Particle Physics at the Terascale; Basso, Lorenzo [Aix-Marseille Univ., CNRS-IN2P3, UMR 7346 (France). CPPM; and others

    2016-02-15

    The hints for a new resonance at 750 GeV from ATLAS and CMS have triggered a significant amount of attention. Since the simplest extensions of the standard model cannot accommodate the observation, many alternatives have been considered to explain the excess. Here we focus on several proposed renormalisable weakly-coupled models and revisit results given in the literature. We point out that physically important subtleties are often missed or neglected. To facilitate the study of the excess we have created a collection of 40 model files, selected from recent literature, for the Mathematica package SARAH. With SARAH one can generate files to perform numerical studies using the tailor-made spectrum generators FlexibleSUSY and SPheno. These have been extended to automatically include crucial higher order corrections to the diphoton and digluon decay rates for both CP-even and CP-odd scalars. Additionally, we have extended the UFO and CalcHep interfaces of SARAH, to pass the precise information about the effective vertices from the spectrum generator to a Monte-Carlo tool. Finally, as an example to demonstrate the power of the entire setup, we present a new supersymmetric model that accommodates the diphoton excess, explicitly demonstrating how a large width can be obtained. We explicitly show several steps in detail to elucidate the use of these public tools in the precision study of this model.

  6. Precision tools and models to narrow in on the 750 GeV diphoton resonance

    International Nuclear Information System (INIS)

    Staub, Florian; Athron, Peter; Basso, Lorenzo; Goodsell, Mark D.; Harries, Dylan; Krauss, Manuel E.; Nickel, Kilian; Opferkuch, Toby; Ubaldi, Lorenzo; Vicente, Avelino; Voigt, Alexander

    2016-01-01

    The hints for a new resonance at 750 GeV from ATLAS and CMS have triggered a significant amount of attention. Since the simplest extensions of the standard model cannot accommodate the observation, many alternatives have been considered to explain the excess. Here we focus on several proposed renormalisable weakly-coupled models and revisit results given in the literature. We point out that physically important subtleties are often missed or neglected. To facilitate the study of the excess we have created a collection of 40 model files, selected from recent literature, for the Mathematica package SARAH. With SARAH one can generate files to perform numerical studies using the tailor-made spectrum generators FlexibleSUSY and SPheno. These have been extended to automatically include crucial higher order corrections to the diphoton and digluon decay rates for both CP-even and CP-odd scalars. Additionally, we have extended the UFO and CalcHep interfaces of SARAH, to pass the precise information about the effective vertices from the spectrum generator to a Monte-Carlo tool. Finally, as an example to demonstrate the power of the entire setup, we present a new supersymmetric model that accommodates the diphoton excess, explicitly demonstrating how a large width can be obtained. We explicitly show several steps in detail to elucidate the use of these public tools in the precision study of this model. (orig.)

  7. Recent Advances in Translational Magnetic Resonance Imaging in Animal Models of Stress and Depression

    Directory of Open Access Journals (Sweden)

    Allison L. McIntosh

    2017-05-01

    Full Text Available Magnetic resonance imaging (MRI is a valuable translational tool that can be used to investigate alterations in brain structure and function in both patients and animal models of disease. Regional changes in brain structure, functional connectivity, and metabolite concentrations have been reported in depressed patients, giving insight into the networks and brain regions involved, however preclinical models are less well characterized. The development of more effective treatments depends upon animal models that best translate to the human condition and animal models may be exploited to assess the molecular and cellular alterations that accompany neuroimaging changes. Recent advances in preclinical imaging have facilitated significant developments within the field, particularly relating to high resolution structural imaging and resting-state functional imaging which are emerging techniques in clinical research. This review aims to bring together the current literature on preclinical neuroimaging in animal models of stress and depression, highlighting promising avenues of research toward understanding the pathological basis of this hugely prevalent disorder.

  8. Large-scale inverse and forward modeling of adaptive resonance in the tinnitus decompensation.

    Science.gov (United States)

    Low, Yin Fen; Trenado, Carlos; Delb, Wolfgang; D'Amelio, Roberto; Falkai, Peter; Strauss, Daniel J

    2006-01-01

    Neural correlates of psychophysiological tinnitus models in humans may be used for their neurophysiological validation as well as for their refinement and improvement to better understand the pathogenesis of the tinnitus decompensation and to develop new therapeutic approaches. In this paper we make use of neural correlates of top-down projections, particularly, a recently introduced synchronization stability measure, together with a multiscale evoked response potential (ERP) model in order to study and evaluate the tinnitus decompensation by using a hybrid inverse-forward mathematical methodology. The neural synchronization stability, which according to the underlying model is linked to the focus of attention on the tinnitus signal, follows the experimental and inverse way and allows to discriminate between a group of compensated and decompensated tinnitus patients. The multiscale ERP model, which works in the forward direction, is used to consolidate hypotheses which are derived from the experiments for a known neural source dynamics related to attention. It is concluded that both methodologies agree and support each other in the description of the discriminatory character of the neural correlate proposed, but also help to fill the gap between the top-down adaptive resonance theory and the Jastreboff model of tinnitus.

  9. Three-dimensional FDTD Modeling of Earth-ionosphere Cavity Resonances

    Science.gov (United States)

    Yang, H.; Pasko, V. P.

    2003-12-01

    Resonance properties of the earth-ionosphere cavity were first predicted by W. O. Schumann in 1952 [Schumann, Z. Naturforsch. A, 7, 149, 1952]. Since then observations of extremely low frequency (ELF) signals in the frequency range 1-500 Hz have become a powerful tool for monitoring of global lightning activity and planetary scale variability of the lower ionosphere, as well as, in recent years, for location and remote sensing of sprites, jets and elves and associated lightning discharges [e.g., Sato et al., JASTP, 65, 607, 2003; Su et al., Nature, 423, 974, 2003; and references cited therein]. The simplicity and flexibility of finite difference time domain (FDTD) technique for finding first principles solutions of electromagnetic problems in a medium with arbitrary inhomogeneities and ever-increasing computer power make FDTD an excellent candidate to be the technique of the future in development of realistic numerical models of VLF/ELF propagation in Earth-ionosphere waveguide [Cummer, IEEE Trans. Antennas Propagat., 48, 1420, 2000], and several reports about successful application of the FDTD technique for solution of related problems have recently appeared in the literature [e.g., Thevenot et al., Ann. Telecommun., 54, 297, 1999; Cummer, 2000; Berenger, Ann. Telecommun., 57, 1059, 2002, Simpson and Taflove, IEEE Antennas Wireless Propagat. Lett., 1, 53, 2002]. In this talk we will present results from a new three-dimensional spherical FDTD model, which is designed for studies of ELF electromagnetic signals under 100 Hz in the earth-ionosphere cavity. The model accounts for a realistic latitudinal and longitudinal variation of ground conductivity (i.e., for the boundaries between oceans and continents) by employing a broadband surface impedance technique proposed in [Breggs et al., IEEE Trans. Antenna Propagat., 41, 118, 1993]. The realistic distributions of atmospheric/lower ionospheric conductivity are derived from the international reference ionosphere model

  10. Enhancement of epidemic spread by noise and stochastic resonance in spatial network models with viral dynamics.

    Science.gov (United States)

    Tuckwell, H C; Toubiana, L; Vibert, J F

    2000-05-01

    We extend a previous dynamical viral network model to include stochastic effects. The dynamical equations for the viral and immune effector densities within a host population of size n are bilinear, and the noise is white, additive, and Gaussian. The individuals are connected with an n x n transmission matrix, with terms which decay exponentially with distance. In a single individual, for the range of noise parameters considered, it is found that increasing the amplitude of the noise tends to decrease the maximum mean virion level, and slightly accelerate its attainment. Two different spatial dynamical models are employed to ascertain the effects of environmental stochasticity on viral spread. In the first model transmission is unrestricted and there is no threshold within individuals. This model has the advantage that it can be analyzed using a Fokker-Planck approach. The noise is found both to synchronize and uniformize the trajectories of the viral levels across the population of infected individuals, and thus to promote the epidemic spread of the virus. Quantitative measures of the speed of spread and overall amplitude of the epidemic are obtained as functions of the noise and virulence parameters. The mean amplitude increases steadily without threshold effects for a fixed value of the virulence as the noise amplitude sigma is increased, and there is no evidence of a stochastic resonance. However, the speed of transmission, both with respect to its mean and variance, undergoes rapid increases as sigma changes by relatively small amounts. In the second, more realistic, model, there is a threshold for infection and an upper limit to the transmission rate. There may be no spread of infection at all in the absence of noise. With increasing noise level and a low threshold, the mean maximum virion level grows quickly and shows a broad-based stochastic resonance effect. When the threshold within individuals is increased, the mean population virion level increases only

  11. Effects of Harbor Modification on Crescent City, California's Tsunami Vulnerability

    Science.gov (United States)

    Dengler, Lori; Uslu, Burak

    2011-06-01

    More damaging tsunamis have impacted Crescent City, California in historic times than any other location on the West Coast of the USA. Crescent City's harbor has undergone significant modification since the early 20th century, including construction of several breakwaters, dredging, and a 200 × 300 m2 small boat basin. In 2006, a M w 8.3 earthquake in the Kuril Islands generated a moderate Pacific-wide tsunami. Crescent City recorded the highest amplitudes of any tide gauge in the Pacific and was the only location to experience structural damage. Strong currents damaged docks and boats within the small boat basin, causing more than US 20 million in damage and replacement costs. We examine how modifications to Crescent City's harbor may have affected its vulnerability to moderate tsunamis such as the 2006 event. A bathymetric grid of the basin was constructed based on US Army Corps of Engineers soundings in 1964 and 1965 before the construction of the small boat basin. The method of splitting tsunamis was used to estimate tsunami water heights and current velocities at several locations in the harbor using both the 1964-1965 grid and the 2006 bathymetric grid for the 2006 Kuril event and a similar-sized source along the Sanriku coast of Japan. Model velocity outputs are compared for the two different bathymetries at the tide gauge location and at six additional computational sites in the harbor. The largest difference between the two grids is at the small boat basin entrance, where the 2006 bathymetry produces currents over three times the strength of the currents produced by the 1965 bathymetry. Peak currents from a Sanriku event are comparable to those produced by the 2006 event, and within the boat basin may have been higher. The modifications of the harbor, and in particular the addition of the small boat basin, appear to have contributed to the high current velocities and resulting damage in 2006 and help to explain why the 1933 M w 8.4-8.7 Sanriku tsunami

  12. Measurement and modeling of nitrogen resonance line profiles from an electrodeless discharge lamp

    International Nuclear Information System (INIS)

    Wood, D.R.; Skinner, G.B.; Lifshitz, A.

    1987-01-01

    Experimental profiles of the 1200 A resonance triplet of atomic nitrogen were measured for a variety of operating conditions of an end-on electrodeless lamp, and corresponding absorption curves were calculated. Each source profile was determined by fitting parameters to an empirical two-layer model, then convoluting with the instrumental function for comparison with experimental data. Each three-component profile was fitted with three adjustable parameters: an absorption parameter for each of the two layers and a third absorption parameter to adjust for radiation trapping. Curves of absorption as a function of atom concentration, calculated from these profiles, are very similar to the shock tube calibrations of Thielen and Roth in which a source of similar design has been used

  13. Stochastic resonance and noise delayed extinction in a model of two competing species

    Science.gov (United States)

    Valenti, D.; Fiasconaro, A.; Spagnolo, B.

    2004-01-01

    We study the role of the noise in the dynamics of two competing species. We consider generalized Lotka-Volterra equations in the presence of a multiplicative noise, which models the interaction between the species and the environment. The interaction parameter between the species is a random process which obeys a stochastic differential equation with a generalized bistable potential in the presence of a periodic driving term, which accounts for the environment temperature variation. We find noise-induced periodic oscillations of the species concentrations and stochastic resonance phenomenon. We find also a nonmonotonic behavior of the mean extinction time of one of the two competing species as a function of the additive noise intensity.

  14. Optimization of a coaxial electron cyclotron resonance plasma thruster with an analytical model

    Energy Technology Data Exchange (ETDEWEB)

    Cannat, F., E-mail: felix.cannat@onera.fr, E-mail: felix.cannat@gmail.com; Lafleur, T. [Physics and Instrumentation Department, Onera -The French Aerospace Lab, Palaiseau, Cedex 91123 (France); Laboratoire de Physique des Plasmas, CNRS, Sorbonne Universites, UPMC Univ Paris 06, Univ Paris-Sud, Ecole Polytechnique, 91128 Palaiseau (France); Jarrige, J.; Elias, P.-Q.; Packan, D. [Physics and Instrumentation Department, Onera -The French Aerospace Lab, Palaiseau, Cedex 91123 (France); Chabert, P. [Laboratoire de Physique des Plasmas, CNRS, Sorbonne Universites, UPMC Univ Paris 06, Univ Paris-Sud, Ecole Polytechnique, 91128 Palaiseau (France)

    2015-05-15

    A new cathodeless plasma thruster currently under development at Onera is presented and characterized experimentally and analytically. The coaxial thruster consists of a microwave antenna immersed in a magnetic field, which allows electron heating via cyclotron resonance. The magnetic field diverges at the thruster exit and forms a nozzle that accelerates the quasi-neutral plasma to generate a thrust. Different thruster configurations are tested, and in particular, the influence of the source diameter on the thruster performance is investigated. At microwave powers of about 30 W and a xenon flow rate of 0.1 mg/s (1 SCCM), a mass utilization of 60% and a thrust of 1 mN are estimated based on angular electrostatic probe measurements performed downstream of the thruster in the exhaust plume. Results are found to be in fair agreement with a recent analytical helicon thruster model that has been adapted for the coaxial geometry used here.

  15. A singular K-space model for fast reconstruction of magnetic resonance images from undersampled data.

    Science.gov (United States)

    Luo, Jianhua; Mou, Zhiying; Qin, Binjie; Li, Wanqing; Ogunbona, Philip; Robini, Marc C; Zhu, Yuemin

    2017-12-09

    Reconstructing magnetic resonance images from undersampled k-space data is a challenging problem. This paper introduces a novel method of image reconstruction from undersampled k-space data based on the concept of singularizing operators and a novel singular k-space model. Exploring the sparsity of an image in the k-space, the singular k-space model (SKM) is proposed in terms of the k-space functions of a singularizing operator. The singularizing operator is constructed by combining basic difference operators. An algorithm is developed to reliably estimate the model parameters from undersampled k-space data. The estimated parameters are then used to recover the missing k-space data through the model, subsequently achieving high-quality reconstruction of the image using inverse Fourier transform. Experiments on physical phantom and real brain MR images have shown that the proposed SKM method constantly outperforms the popular total variation (TV) and the classical zero-filling (ZF) methods regardless of the undersampling rates, the noise levels, and the image structures. For the same objective quality of the reconstructed images, the proposed method requires much less k-space data than the TV method. The SKM method is an effective method for fast MRI reconstruction from the undersampled k-space data. Graphical abstract Two Real Images and their sparsified images by singularizing operator.

  16. Summary of oceanographic and water–quality measurements in West Falmouth Harbor and Buzzards Bay, Massachusetts, 2009–2010

    Science.gov (United States)

    Ganju, Neil K.; Dickhudt, Patrick J.; Thomas, Jennifer A.; Borden, Jonathan; Sherwood, Christopher R.; Montgomery, Ellyn T.; Twomey, Erin R.; Martini, Marinna A.

    2011-01-01

    This data report presents oceanographic and water-quality observations made at six locations in West Falmouth Harbor and Buzzards Bay, Massachusetts, from August 2009 to September 2010. Both Buzzards Bay and West Falmouth Harbor are estuarine embayments; the input of freshwater on the eastern margin of Buzzards Bay adjacent to Cape Cod and West Falmouth Harbor is largely due to groundwater. In West Falmouth Harbor, the groundwater that seeps into the harbor is characterized by relatively high levels of nitrate. This high nitrate load has modified the ecology of the harbor (Howes and others, 2006) and may be a significant source of nitrate to Buzzards Bay during seasons with low biological nitrate uptake. The U.S. Geological Survey undertook these measurements to improve understanding of circulation, residence time, and water quality in the harbor and bay. We set up and monitored multiple sites in both Buzzards Bay and West Falmouth Harbor, measuring depth, water velocity,salinity, pH, dissolved oxygen, chlorophyll-a, and nitrate concentration. In this report we present the processed time-series data at these locations and provide access to the data and metadata. The results will be used to understand circulation mechanisms and verify numerical models of hydrodynamics and biogeochemistry.

  17. Multiquark Resonances

    CERN Document Server

    Esposito, A.; Polosa, A.D.

    2016-01-01

    Multiquark resonances are undoubtedly experimentally observed. The number of states and the amount of details on their properties has been growing over the years. It is very recent the discovery of two pentaquarks and the confirmation of four tetraquarks, two of which had not been observed before. We mainly review the theoretical understanding of this sector of particle physics phenomenology and present some considerations attempting a coherent description of the so called X and Z resonances. The prominent problems plaguing theoretical models, like the absence of selection rules limiting the number of states predicted, motivate new directions in model building. Data are reviewed going through all of the observed resonances with particular attention to their common features and the purpose of providing a starting point to further research.

  18. Modelling and characterization of the roof tile-shaped modes of AlN-based cantilever resonators in liquid media

    International Nuclear Information System (INIS)

    Ruiz-Díez, V; Hernando-García, J; Toledo, J; Manzaneque, T; Sánchez-Rojas, J L; Kucera, M; Pfusterschmied, G; Schmid, U

    2016-01-01

    In this work, roof tile-shaped modes of MEMS (micro electro-mechanical systems) cantilever resonators with various geometries and mode orders are analysed. These modes can be efficiently excited by a thin piezoelectric film and a properly designed top electrode. The electrical and optical characterization of the resonators are performed in liquid media and the device performance is evaluated in terms of quality factor, resonant frequency and motional conductance. A quality factor as high as 165 was measured in isopropanol for a cantilever oscillating in the seventh order roof tile-shaped mode at 2 MHz. To support the results of the experimental characterization, a 2D finite element method simulation model is presented and studied. An analytical model for the estimation of the motional conductance was also developed and validated with the experimental measurements. (paper)

  19. Fiducial-based fusion of 3D dental models with magnetic resonance imaging.

    Science.gov (United States)

    Abdi, Amir H; Hannam, Alan G; Fels, Sidney

    2018-04-16

    Magnetic resonance imaging (MRI) is widely used in study of maxillofacial structures. While MRI is the modality of choice for soft tissues, it fails to capture hard tissues such as bone and teeth. Virtual dental models, acquired by optical 3D scanners, are becoming more accessible for dental practice and are starting to replace the conventional dental impressions. The goal of this research is to fuse the high-resolution 3D dental models with MRI to enhance the value of imaging for applications where detailed analysis of maxillofacial structures are needed such as patient examination, surgical planning, and modeling. A subject-specific dental attachment was digitally designed and 3D printed based on the subject's face width and dental anatomy. The attachment contained 19 semi-ellipsoidal concavities in predetermined positions where oil-based ellipsoidal fiducial markers were later placed. The MRI was acquired while the subject bit on the dental attachment. The spatial position of the center of mass of each fiducial in the resultant MR Image was calculated by averaging its voxels' spatial coordinates. The rigid transformation to fuse dental models to MRI was calculated based on the least squares mapping of corresponding fiducials and solved via singular-value decomposition. The target registration error (TRE) of the proposed fusion process, calculated in a leave-one-fiducial-out fashion, was estimated at 0.49 mm. The results suggest that 6-9 fiducials suffice to achieve a TRE of equal to half the MRI voxel size. Ellipsoidal oil-based fiducials produce distinguishable intensities in MRI and can be used as registration fiducials. The achieved accuracy of the proposed approach is sufficient to leverage the merged 3D dental models with the MRI data for a finer analysis of the maxillofacial structures where complete geometry models are needed.

  20. Numerical examinations of simplified spondylodesis models concerning energy absorption in magnetic resonance imaging

    Directory of Open Access Journals (Sweden)

    Hadert Nicole

    2016-09-01

    Full Text Available Metallic implants in magnetic resonance imaging (MRI are a potential safety risk since the energy absorption may increase temperature of the surrounding tissue. The temperature rise is highly dependent on implant size. Numerical examinations can be used to calculate the energy absorption in terms of the specific absorption rate (SAR induced by MRI on orthopaedic implants. This research presents the impact of titanium osteosynthesis spine implants, called spondylodesis, deduced by numerical examinations of energy absorption in simplified spondylodesis models placed in 1.5 T and 3.0 T MRI body coils. The implants are modelled along with a spine model consisting of vertebrae and disci intervertebrales thus extending previous investigations [1], [2]. Increased SAR values are observed at the ends of long implants, while at the center SAR is significantly lower. Sufficiently short implants show increased SAR along the complete length of the implant. A careful data analysis reveals that the particular anatomy, i.e. vertebrae and disci intervertebrales, has a significant effect on SAR. On top of SAR profile due to the implant length, considerable SAR variations at small scale are observed, e.g. SAR values at vertebra are higher than at disc positions.

  1. Precision tools and models to narrow in on the 750 GeV diphoton resonance

    CERN Document Server

    Staub, Florian; Basso, Lorenzo; Goodsell, Mark D.; Harries, Dylan; Krauss, Manuel E.; Nickel, Kilian; Opferkuch, Toby; Ubaldi, Lorenzo; Vicente, Avelino; Voigt, Alexander

    2016-09-23

    The hints for a new resonance at 750 GeV from ATLAS and CMS have triggered a significant amount of attention. Since the simplest extensions of the standard model cannot accommodate the observation, many alternatives have been considered to explain the excess. Here we focus on several proposed renormalisable weakly-coupled models and revisit results given in the literature. We point out that physically important subtleties are often missed or neglected. To facilitate the study of the excess we have created a collection of 40 model files, selected from recent literature, for the Mathematica package SARAH. With SARAH one can generate files to perform numerical studies using the tailor-made spectrum generators FlexibleSUSY and SPheno. These have been extended to automatically include crucial higher order corrections to the diphoton and digluon decay rates for both CP-even and CP-odd scalars. Additionally, we have extended the UFO and CalcHep interfaces of SARAH, to pass the precise information about the effective...

  2. Metabolomics with Nuclear Magnetic Resonance Spectroscopy in a Drosophila melanogaster Model of Surviving Sepsis

    Science.gov (United States)

    Bakalov, Veli; Amathieu, Roland; Triba, Mohamed N.; Clément, Marie-Jeanne; Reyes Uribe, Laura; Le Moyec, Laurence; Kaynar, Ata Murat

    2016-01-01

    Patients surviving sepsis demonstrate sustained inflammation, which has been associated with long-term complications. One of the main mechanisms behind sustained inflammation is a metabolic switch in parenchymal and immune cells, thus understanding metabolic alterations after sepsis may provide important insights to the pathophysiology of sepsis recovery. In this study, we explored metabolomics in a novel Drosophila melanogaster model of surviving sepsis using Nuclear Magnetic Resonance (NMR), to determine metabolite profiles. We used a model of percutaneous infection in Drosophila melanogaster to mimic sepsis. We had three experimental groups: sepsis survivors (infected with Staphylococcus aureus and treated with oral linezolid), sham (pricked with an aseptic needle), and unmanipulated (positive control). We performed metabolic measurements seven days after sepsis. We then implemented metabolites detected in NMR spectra into the MetExplore web server in order to identify the metabolic pathway alterations in sepsis surviving Drosophila. Our NMR metabolomic approach in a Drosophila model of recovery from sepsis clearly distinguished between all three groups and showed two different metabolomic signatures of inflammation. Sham flies had decreased levels of maltose, alanine, and glutamine, while their level of choline was increased. Sepsis survivors had a metabolic signature characterized by decreased glucose, maltose, tyrosine, beta-alanine, acetate, glutamine, and succinate. PMID:28009836

  3. Memory-induced resonancelike suppression of spike generation in a resonate-and-fire neuron model

    Science.gov (United States)

    Mankin, Romi; Paekivi, Sander

    2018-01-01

    The behavior of a stochastic resonate-and-fire neuron model based on a reduction of a fractional noise-driven generalized Langevin equation (GLE) with a power-law memory kernel is considered. The effect of temporally correlated random activity of synaptic inputs, which arise from other neurons forming local and distant networks, is modeled as an additive fractional Gaussian noise in the GLE. Using a first-passage-time formulation, in certain system parameter domains exact expressions for the output interspike interval (ISI) density and for the survival probability (the probability that a spike is not generated) are derived and their dependence on input parameters, especially on the memory exponent, is analyzed. In the case of external white noise, it is shown that at intermediate values of the memory exponent the survival probability is significantly enhanced in comparison with the cases of strong and weak memory, which causes a resonancelike suppression of the probability of spike generation as a function of the memory exponent. Moreover, an examination of the dependence of multimodality in the ISI distribution on input parameters shows that there exists a critical memory exponent αc≈0.402 , which marks a dynamical transition in the behavior of the system. That phenomenon is illustrated by a phase diagram describing the emergence of three qualitatively different structures of the ISI distribution. Similarities and differences between the behavior of the model at internal and external noises are also discussed.

  4. 32 CFR 765.6 - Regulations for Pearl Harbor, Hawaii.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Regulations for Pearl Harbor, Hawaii. 765.6... RULES RULES APPLICABLE TO THE PUBLIC § 765.6 Regulations for Pearl Harbor, Hawaii. The Commander, U.S. Naval Base, Pearl Harbor, Hawaii, is responsible for prescribing and enforcing such rules and...

  5. Teaching about Pearl Harbor. Curriculum Enhancement Series #1.

    Science.gov (United States)

    Shields, Anna Marshall

    These materials consist of sample lesson plans for teaching about the Japanese attack on Pearl Harbor on December 7, 1941, in both U.S. and world history classes. The lesson plans challenge students to examine how current attitudes toward the Japanese may be rooted in World War II and Pearl Harbor. Selected bibliographies on Pearl Harbor, World…

  6. Automated prostate cancer detection via comprehensive multi-parametric magnetic resonance imaging texture feature models

    International Nuclear Information System (INIS)

    Khalvati, Farzad; Wong, Alexander; Haider, Masoom A.

    2015-01-01

    Prostate cancer is the most common form of cancer and the second leading cause of cancer death in North America. Auto-detection of prostate cancer can play a major role in early detection of prostate cancer, which has a significant impact on patient survival rates. While multi-parametric magnetic resonance imaging (MP-MRI) has shown promise in diagnosis of prostate cancer, the existing auto-detection algorithms do not take advantage of abundance of data available in MP-MRI to improve detection accuracy. The goal of this research was to design a radiomics-based auto-detection method for prostate cancer via utilizing MP-MRI data. In this work, we present new MP-MRI texture feature models for radiomics-driven detection of prostate cancer. In addition to commonly used non-invasive imaging sequences in conventional MP-MRI, namely T2-weighted MRI (T2w) and diffusion-weighted imaging (DWI), our proposed MP-MRI texture feature models incorporate computed high-b DWI (CHB-DWI) and a new diffusion imaging modality called correlated diffusion imaging (CDI). Moreover, the proposed texture feature models incorporate features from individual b-value images. A comprehensive set of texture features was calculated for both the conventional MP-MRI and new MP-MRI texture feature models. We performed feature selection analysis for each individual modality and then combined best features from each modality to construct the optimized texture feature models. The performance of the proposed MP-MRI texture feature models was evaluated via leave-one-patient-out cross-validation using a support vector machine (SVM) classifier trained on 40,975 cancerous and healthy tissue samples obtained from real clinical MP-MRI datasets. The proposed MP-MRI texture feature models outperformed the conventional model (i.e., T2w+DWI) with regard to cancer detection accuracy. Comprehensive texture feature models were developed for improved radiomics-driven detection of prostate cancer using MP-MRI. Using a

  7. Search for tt-bar resonances and implications for new physics models

    International Nuclear Information System (INIS)

    Khalatyan, S.

    2014-01-01

    CMS and ATLAS experiments searched for top quark pair resonances using 2001 data recorded in pp collisions at √(s)=7 TeV at the Large Hadron Collider in all final states: dilepton, lepton+jets, and all hadronic. No significant deviation over backgrounds are observed. The experiments have set 95% confidence level upper limits on the resonance production cross section times branching ratio, and reported the excluded resonance mass region. (author)

  8. Magnetic resonance imaging of an equine fracture model containing stainless steel metal implants.

    Science.gov (United States)

    Pownder, S L; Koff, M F; Shah, P H; Fortier, L A; Potter, H G

    2016-05-01

    Post operative imaging in subjects with orthopaedic implants is challenging across all modalities. Magnetic resonance imaging (MRI) is preferred to assess human post operative musculoskeletal complications, as soft tissue and bones are evaluated without using ionising radiation. However, with conventional MRI pulse sequences, metal creates susceptibility artefact that distorts anatomy. Assessment of the post operative equine patient is arguably more challenging due to the volume of metal present, and MRI is often not performed in horses with implants. Novel pulse sequences such as multiacquisition variable resonance image combination (MAVRIC) now provide improved visibility in the vicinity of surgical-grade implants and offer an option for imaging horses with metal implants. To compare conspicuity of regional anatomy in an equine fracture-repair model using MAVRIC, narrow receiver bandwidth (NBW) fast spin echo (FSE), and wide receiver bandwidth (WBW) FSE sequences. Nonrandomised in vitro experiment. MAVRIC, NBW FSE and WBW FSE were performed on 9 cadaveric distal limbs with fractures and stainless steel implants in the third metacarpal bone and proximal phalanx. Objective measures of artefact reduction were performed by calculating the total artefact area in each transverse image as a percentage of the total anatomic area. The number of transverse images in which fracture lines were visible was tabulated for each sequence. Regional soft tissue conspicuity was assessed subjectively. Overall anatomic delineation was improved using MAVRIC compared with NBW FSE; delineation of structures closest to the metal implants was improved using MAVRIC compared with WBW FSE and NBW FSE. Total artefact area was the highest for NBW FSE and lowest for MAVRIC; the total number of transverse slices with a visible fracture line was highest in MAVRIC and lowest in NBW FSE. MAVRIC and WBW FSE are feasible additions to minimise artefact around implants. © 2015 EVJ Ltd.

  9. Remembering Pearl Harbor at 75 Years.

    Science.gov (United States)

    Liehr, Patricia; Sopcheck, Janet; Milbrath, Gwyneth

    2016-12-01

    : On December 7, 1941, the Sunday-morning quiet of the U.S. naval base in Pearl Harbor, Hawaii, was shattered by dive-bombing Japanese fighter planes. The planes came in two waves-and when it was all over, more than 2,400 were killed and more than 1,100 were injured.Nurses were stationed at U.S. Naval Hospital Pearl Harbor, Tripler General Hospital (now Tripler Army Medical Center), Hickam Field Hospital, Schofield Barracks Station Hospital, and aboard the USS Solace, and witnessed the devastation. But they also did what nurses do in emergencies-they responded and provided care to those in need. Here are the stories of a few of those nurses.

  10. Old Harbor Scammon Bay Hydro Feasibility

    Energy Technology Data Exchange (ETDEWEB)

    Brent Petrie

    2007-06-27

    The grantee, Alaska Village Electric Cooperative (AVEC), is a non-profit member owned rural electric generation and distribution cooperative. The proposed Project is located near the community of Old Harbor, Alaska. Old Harbor is on the southeastern coast of Kodiak Island, approximately 70 miles southwest of the City of Kodiak and 320 miles southwest of Anchorage. In 1998 sufficient information had been developed to apply for a license to construct the project and the cost was estimated to be $2,445,000 for a 500 KW project on Lagoon Creek. Major features of the project included an eight-foot high diversion dam on Mountain Creek, a desander box, a 9,800-foot long penstock to the powerhouse on Lagoon Creek, and a 5,500-foot long access road. It was also anticipated that the project could provide an additional source of water to Old Harbor. The report details the history and lessons learned in designing and permiting the proposed hydroelectric facility.

  11. Effects of magnetic resonance-guided high-intensity focused ultrasound ablation on bone mechanical properties and modeling

    NARCIS (Netherlands)

    Yeoh, S.Y.; Arias Moreno, A.J.; Rietbergen, van B.; Hoeve, ter N.D.; Diest, van P.J.; Grull, H.

    2015-01-01

    Background Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) is a promising technique for palliative treatment of bone pain. In this study, the effects of MR-HIFU ablation on bone mechanics and modeling were investigated. Methods A total of 12 healthy rat femurs were ablated

  12. Interacting sp-boson model with isospin: an unified description of giant multipole resonances and other collective motions

    International Nuclear Information System (INIS)

    Chen, C.H.-T.

    1980-10-01

    A unified description of the following classes of nuclear collective states in terms of an interacting sp-boson model is proposed: (i) Low-lying collective states in the light nuclei, both odd-odd and even-even; (ii) Giant multipole resonances (GMR), and (iii) pairing collective motions. (Author) [pt

  13. A comparative Pc1 case study applying two modes of ionospheric Alfvén resonator modeling

    Czech Academy of Sciences Publication Activity Database

    Prikner, Karel; Feygin, F. Z.; Raita, T.

    2010-01-01

    Roč. 54, č. 3 (2010), s. 495-511 ISSN 0039-3169 Grant - others:EU(XE) HPRI 200100132 Institutional research plan: CEZ:AV0Z30120515 Keywords : ionospheric Alfvén resonator * Pc1 pulsations * numerical simulation * EISCAT data * IRI models Subject RIV: DE - Earth Magnetism, Geodesy, Geography Impact factor: 1.123, year: 2010

  14. Magnetic resonance imaging of reconstructed ferritin as an iron-induced pathological model system

    Energy Technology Data Exchange (ETDEWEB)

    Balejcikova, Lucia [Institute of Experimental Physics SAS, Watsonova 47, 040 01 Kosice (Slovakia); Institute of Measurement Science SAS, Dubravska cesta 9, 841 04 Bratislava 4 (Slovakia); Strbak, Oliver [Institute of Measurement Science SAS, Dubravska cesta 9, 841 04 Bratislava 4 (Slovakia); Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Mala Hora 4, 036 01 Martin (Slovakia); Baciak, Ladislav [Faculty of Chemical and Food Technology STU, Radlinskeho 9, 812 37 Bratislava (Slovakia); Kovac, Jozef [Institute of Experimental Physics SAS, Watsonova 47, 040 01 Kosice (Slovakia); Masarova, Marta; Krafcik, Andrej; Frollo, Ivan [Institute of Measurement Science SAS, Dubravska cesta 9, 841 04 Bratislava 4 (Slovakia); Dobrota, Dusan [Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Mala Hora 4, 036 01 Martin (Slovakia); Kopcansky, Peter [Institute of Experimental Physics SAS, Watsonova 47, 040 01 Kosice (Slovakia)

    2017-04-01

    Iron, an essential element of the human body, is a significant risk factor, particularly in the case of its concentration increasing above the specific limit. Therefore, iron is stored in the non-toxic form of the globular protein, ferritin, consisting of an apoferritin shell and iron core. Numerous studies confirmed the disruption of homeostasis and accumulation of iron in patients with various diseases (e.g. cancer, cardiovascular or neurological conditions), which is closely related to ferritin metabolism. Such iron imbalance enables the use of magnetic resonance imaging (MRI) as a sensitive technique for the detection of iron-based aggregates through changes in the relaxation times, followed by the change in the inherent image contrast. For our in vitrostudy, modified ferritins with different iron loadings were prepared by chemical reconstruction of the iron core in an apoferritin shell as pathological model systems. The magnetic properties of samples were studied using SQUID magnetometry, while the size distribution was detected via dynamic light scattering. We have shown that MRI could represent the most advantageous method for distinguishing native ferritin from reconstructed ferritin which, after future standardisation, could then be suitable for the diagnostics of diseases associated with iron accumulation. - Highlights: • MRI is the sensitive technique for detecting iron-based aggregates. • Reconstructed Ferritin is suitable model system of iron-related disorders. • MRI allow distinguish of native ferritin from reconstructed ferritin. • MRI could be useful for diagnostics of diseases associated with iron accumulation.

  15. A numerically efficient damping model for acoustic resonances in microfluidic cavities

    Energy Technology Data Exchange (ETDEWEB)

    Hahn, P., E-mail: hahnp@ethz.ch; Dual, J. [Institute of Mechanical Systems (IMES), Department of Mechanical and Process Engineering, ETH Zurich, Tannenstrasse 3, CH-8092 Zurich (Switzerland)

    2015-06-15

    Bulk acoustic wave devices are typically operated in a resonant state to achieve enhanced acoustic amplitudes and high acoustofluidic forces for the manipulation of microparticles. Among other loss mechanisms related to the structural parts of acoustofluidic devices, damping in the fluidic cavity is a crucial factor that limits the attainable acoustic amplitudes. In the analytical part of this study, we quantify all relevant loss mechanisms related to the fluid inside acoustofluidic micro-devices. Subsequently, a numerical analysis of the time-harmonic visco-acoustic and thermo-visco-acoustic equations is carried out to verify the analytical results for 2D and 3D examples. The damping results are fitted into the framework of classical linear acoustics to set up a numerically efficient device model. For this purpose, all damping effects are combined into an acoustofluidic loss factor. Since some components of the acoustofluidic loss factor depend on the acoustic mode shape in the fluid cavity, we propose a two-step simulation procedure. In the first step, the loss factors are deduced from the simulated mode shape. Subsequently, a second simulation is invoked, taking all losses into account. Owing to its computational efficiency, the presented numerical device model is of great relevance for the simulation of acoustofluidic particle manipulation by means of acoustic radiation forces or acoustic streaming. For the first time, accurate 3D simulations of realistic micro-devices for the quantitative prediction of pressure amplitudes and the related acoustofluidic forces become feasible.

  16. Exact calculation of the time convolutionless master equation generator: Application to the nonequilibrium resonant level model

    Science.gov (United States)

    Kidon, Lyran; Wilner, Eli Y.; Rabani, Eran

    2015-12-01

    The generalized quantum master equation provides a powerful tool to describe the dynamics in quantum impurity models driven away from equilibrium. Two complementary approaches, one based on Nakajima-Zwanzig-Mori time-convolution (TC) and the other on the Tokuyama-Mori time-convolutionless (TCL) formulations provide a starting point to describe the time-evolution of the reduced density matrix. A key in both approaches is to obtain the so called "memory kernel" or "generator," going beyond second or fourth order perturbation techniques. While numerically converged techniques are available for the TC memory kernel, the canonical approach to obtain the TCL generator is based on inverting a super-operator in the full Hilbert space, which is difficult to perform and thus, nearly all applications of the TCL approach rely on a perturbative scheme of some sort. Here, the TCL generator is expressed using a reduced system propagator which can be obtained from system observables alone and requires the calculation of super-operators and their inverse in the reduced Hilbert space rather than the full one. This makes the formulation amenable to quantum impurity solvers or to diagrammatic techniques, such as the nonequilibrium Green's function. We implement the TCL approach for the resonant level model driven away from equilibrium and compare the time scales for the decay of the generator with that of the memory kernel in the TC approach. Furthermore, the effects of temperature, source-drain bias, and gate potential on the TCL/TC generators are discussed.

  17. A fractal derivative model for the characterization of anomalous diffusion in magnetic resonance imaging

    Science.gov (United States)

    Liang, Yingjie; Ye, Allen Q.; Chen, Wen; Gatto, Rodolfo G.; Colon-Perez, Luis; Mareci, Thomas H.; Magin, Richard L.

    2016-10-01

    Non-Gaussian (anomalous) diffusion is wide spread in biological tissues where its effects modulate chemical reactions and membrane transport. When viewed using magnetic resonance imaging (MRI), anomalous diffusion is characterized by a persistent or 'long tail' behavior in the decay of the diffusion signal. Recent MRI studies have used the fractional derivative to describe diffusion dynamics in normal and post-mortem tissue by connecting the order of the derivative with changes in tissue composition, structure and complexity. In this study we consider an alternative approach by introducing fractal time and space derivatives into Fick's second law of diffusion. This provides a more natural way to link sub-voxel tissue composition with the observed MRI diffusion signal decay following the application of a diffusion-sensitive pulse sequence. Unlike previous studies using fractional order derivatives, here the fractal derivative order is directly connected to the Hausdorff fractal dimension of the diffusion trajectory. The result is a simpler, computationally faster, and more direct way to incorporate tissue complexity and microstructure into the diffusional dynamics. Furthermore, the results are readily expressed in terms of spectral entropy, which provides a quantitative measure of the overall complexity of the heterogeneous and multi-scale structure of biological tissues. As an example, we apply this new model for the characterization of diffusion in fixed samples of the mouse brain. These results are compared with those obtained using the mono-exponential, the stretched exponential, the fractional derivative, and the diffusion kurtosis models. Overall, we find that the order of the fractal time derivative, the diffusion coefficient, and the spectral entropy are potential biomarkers to differentiate between the microstructure of white and gray matter. In addition, we note that the fractal derivative model has practical advantages over the existing models from the

  18. Competitive resonance interference models in direct whole core transport code nTRACER

    Energy Technology Data Exchange (ETDEWEB)

    Bacha, Meer; Joo, Han Gyu [Seoul National Univ., Seoul (Korea, Republic of)

    2015-05-15

    The capability of nTRACER was enhanced with WIMS IAEA library using the equivalence theory and Dancoff correction method based on the resonance integral data. The background XSs, for the heterogeneous system, incorporating the shadowing effects, are evaluated by the enhanced neutron current method. The effective XSs are generated using the Resonance Integral (RI) data by interpolating for background XSs and temperatures. The conventional method, which augments the background XS with average absorption XSs of all other resonant isotopes in the mixture, is used for treating the resonance interference in mixed resonant absorbers. A lot of methods are being developed for the resonance self-shielding in mixed absorbers, but still there exists some inadequacy in the XSs evaluation. The most accurate method is solving the UFG slowing down equation, but at the cost of huge computational burden. On the other hand, the conventional method is the simplest and easy to implement, but it has drawback, that it can't correctly estimate the cross sections in mixed absorbers because it adds the absorption XS. The resonance interference treatment methods are studied and implemented in nTRACER and checked the capacity to improve the overlap effects for multiple resonant isotopes. In XST method, the XSs are improved a lot as compared to conventional method, but still there exists discrepancy in the lower energy range. This method is very fast having no burden during execution.

  19. ULF Waves in the Ionospheric Alfven Resonator: Modeling of MICA Observations

    Science.gov (United States)

    Streltsov, A. V.; Tulegenov, B.

    2017-12-01

    We present results from a numerical study of physical processes responsible for the generation of small-scale, intense electromagnetic structures in the ultra-low-frequency range frequently observed in the close vicinity of bright discrete auroral arcs. In particular, our research is focused on the role of the ionosphere in generating these structures. A significant body of observations demonstrate that small-scale electromagnetic waves with frequencies below 1 Hz are detected at high latitudes where the large-scale, downward magnetic field-aligned current (FAC) interact with the ionosphere. Some theoretical studies suggest that these waves can be generated by the ionospheric feedback instability (IFI) inside the ionospheric Alfven resonator (IAR). The IAR is the region in the low-altitude magnetosphere bounded by the strong gradient in the Alfven speed at high altitude and the conducting bottom of the ionosphere (ionospheric E-region) at low altitude. To study ULF waves in this region we use a numerical model developed from reduced two fluid MHD equations describing shear Alfven waves in the ionosphere and magnetosphere of the earth. The active ionospheric feedback on structure and amplitude of magnetic FACs that interact with the ionosphere is implemented through the ionospheric boundary conditions that link the parallel current density with the plasma density and the perpendicular electric field in the ionosphere. Our numerical results are compared with the in situ measurements performed by the Magnetosphere-Ionosphere Coupling in the Alfven Resonator (MICA) sounding rocket, launched on February 19, 2012 from Poker Flat Research Range in Alaska to measure fields and particles during a passage through a discreet auroral arc. Parameters of the simulations are chosen to match actual MICA parameters, allowing the comparison in the most precise and rigorous way. Waves generated in the numerical model have frequencies between 0.30 and 0.45 Hz, while MICA measured

  20. Application of catastrophe theory to a point model for bumpy torus with neoclassical non-resonant electrons

    Energy Technology Data Exchange (ETDEWEB)

    Punjabi, A; Vahala, G [College of William and Mary, Williamsburg, VA (USA). Dept. of Physics

    1983-12-01

    The point model for the toroidal core plasma in the ELMO Bumpy Torus (with neoclassical non-resonant electrons) is examined in the light of catastrophe theory. Even though the point model equations do not constitute a gradient dynamic system, the equilibrium surfaces are similar to those of the canonical cusp catastrophe. The point model is then extended to incorporate ion cyclotron resonance heating. A detailed parametric study of the equilibria is presented. Further, the nonlinear time evolution of these equilibria is studied, and it is observed that the point model obeys the delay convention (and hence hysteresis) and shows catastrophes at the fold edges of the equilibrium surfaces. Tentative applications are made to experimental results.

  1. Building a Unified Computational Model for the Resonant X-Ray Scattering of Strongly Correlated Materials

    Energy Technology Data Exchange (ETDEWEB)

    Bansil, Arun [Northeastern Univ., Boston, MA (United States)

    2016-12-01

    Basic-Energy Sciences of the Department of Energy (BES/DOE) has made large investments in x-ray sources in the U.S. (NSLS-II, LCLS, NGLS, ALS, APS) as powerful enabling tools for opening up unprecedented new opportunities for exploring properties of matter at various length and time scales. The coming online of the pulsed photon source literally allows us to see and follow the dynamics of processes in materials at their natural timescales. There is an urgent need therefore to develop theoretical methodologies and computational models for understanding how x-rays interact with matter and the related spectroscopies of materials. The present project addressed aspects of this grand challenge of X-ray science. In particular, our Collaborative Research Team (CRT) focused on understanding and modeling of elastic and inelastic resonant X-ray scattering processes. We worked to unify the three different computational approaches currently used for modeling X-ray scattering—density functional theory, dynamical mean-field theory, and small-cluster exact diagonalization—to achieve a more realistic material-specific picture of the interaction between X-rays and complex matter. To achieve a convergence in the interpretation and to maximize complementary aspects of different theoretical methods, we concentrated on the cuprates, where most experiments have been performed. Our team included both US and international researchers, and it fostered new collaborations between researchers currently working with different approaches. In addition, we developed close relationships with experimental groups working in the area at various synchrotron facilities in the US. Our CRT thus helped toward enabling the US to assume a leadership role in the theoretical development of the field, and to create a global network and community of scholars dedicated to X-ray scattering research.

  2. Building a Unified Computational Model for the Resonant X-Ray Scattering of Strongly Correlated Materials

    International Nuclear Information System (INIS)

    Bansil, Arun

    2016-01-01

    Basic-Energy Sciences of the Department of Energy (BES/DOE) has made large investments in x-ray sources in the U.S. (NSLS-II, LCLS, NGLS, ALS, APS) as powerful enabling tools for opening up unprecedented new opportunities for exploring properties of matter at various length and time scales. The coming online of the pulsed photon source literally allows us to see and follow the dynamics of processes in materials at their natural timescales. There is an urgent need therefore to develop theoretical methodologies and computational models for understanding how x-rays interact with matter and the related spectroscopies of materials. The present project addressed aspects of this grand challenge of X-ray science. In particular, our Collaborative Research Team (CRT) focused on understanding and modeling of elastic and inelastic resonant X-ray scattering processes. We worked to unify the three different computational approaches currently used for modeling X-ray scattering-density functional theory, dynamical mean-field theory, and small-cluster exact diagonalization-to achieve a more realistic material-specific picture of the interaction between X-rays and complex matter. To achieve a convergence in the interpretation and to maximize complementary aspects of different theoretical methods, we concentrated on the cuprates, where most experiments have been performed. Our team included both US and international researchers, and it fostered new collaborations between researchers currently working with different approaches. In addition, we developed close relationships with experimental groups working in the area at various synchrotron facilities in the US. Our CRT thus helped toward enabling the US to assume a leadership role in the theoretical development of the field, and to create a global network and community of scholars dedicated to X-ray scattering research.

  3. Edge Sharpness Assessment by Parametric Modeling: Application to Magnetic Resonance Imaging.

    Science.gov (United States)

    Ahmad, R; Ding, Y; Simonetti, O P

    2015-05-01

    In biomedical imaging, edge sharpness is an important yet often overlooked image quality metric. In this work, a semi-automatic method to quantify edge sharpness in the presence of significant noise is presented with application to magnetic resonance imaging (MRI). The method is based on parametric modeling of image edges. First, an edge map is automatically generated and one or more edges-of-interest (EOI) are manually selected using graphical user interface. Multiple exclusion criteria are then enforced to eliminate edge pixels that are potentially not suitable for sharpness assessment. Second, at each pixel of the EOI, an image intensity profile is read along a small line segment that runs locally normal to the EOI. Third, the profiles corresponding to all EOI pixels are individually fitted with a sigmoid function characterized by four parameters, including one that represents edge sharpness. Last, the distribution of the sharpness parameter is used to quantify edge sharpness. For validation, the method is applied to simulated data as well as MRI data from both phantom imaging and cine imaging experiments. This method allows for fast, quantitative evaluation of edge sharpness even in images with poor signal-to-noise ratio. Although the utility of this method is demonstrated for MRI, it can be adapted for other medical imaging applications.

  4. Modelling the nonlinear behaviour of double walled carbon nanotube based resonator with curvature factors

    Science.gov (United States)

    Patel, Ajay M.; Joshi, Anand Y.

    2016-10-01

    This paper deals with the nonlinear vibration analysis of a double walled carbon nanotube based mass sensor with curvature factor or waviness, which is doubly clamped at a source and a drain. Nonlinear vibrational behaviour of a double-walled carbon nanotube excited harmonically near its primary resonance is considered. The double walled carbon nanotube is harmonically excited by the addition of an excitation force. The modelling involves stretching of the mid plane and damping as per phenomenon. The equation of motion involves four nonlinear terms for inner and outer tubes of DWCNT due to the curved geometry and the stretching of the central plane due to the boundary conditions. The vibrational behaviour of the double walled carbon nanotube with different surface deviations along its axis is analyzed in the context of the time response, Poincaré maps and Fast Fourier Transformation diagrams. The appearance of instability and chaos in the dynamic response is observed as the curvature factor on double walled carbon nanotube is changed. The phenomenon of Periodic doubling and intermittency are observed as the pathway to chaos. The regions of periodic, sub-harmonic and chaotic behaviour are clearly seen to be dependent on added mass and the curvature factors in the double walled carbon nanotube. Poincaré maps and frequency spectra are used to explicate and to demonstrate the miscellany of the system behaviour. With the increase in the curvature factor system excitations increases and results in an increase of the vibration amplitude with reduction in excitation frequency.

  5. Magnetic resonance imaging (MRI to study striatal iron accumulation in a rat model of Parkinson's disease.

    Directory of Open Access Journals (Sweden)

    Ana Virel

    Full Text Available Abnormal accumulation of iron is observed in neurodegenerative disorders. In Parkinson's disease, an excess of iron has been demonstrated in different structures of the basal ganglia and is suggested to be involved in the pathogenesis of the disease. Using the 6-hydroxydopamine (6-OHDA rat model of Parkinson's disease, the edematous effect of 6-OHDA and its relation with striatal iron accumulation was examined utilizing in vivo magnetic resonance imaging (MRI. The results revealed that in comparison with control animals, injection of 6-OHDA into the rat striatum provoked an edematous process, visible in T2-weighted images that was accompanied by an accumulation of iron clearly detectable in T2*-weighted images. Furthermore, Prussian blue staining to detect iron in sectioned brains confirmed the existence of accumulated iron in the areas of T2* hypointensities. The presence of ED1-positive microglia in the lesioned striatum overlapped with this accumulation of iron, indicating areas of toxicity and loss of dopamine nerve fibers. Correlation analyses demonstrated a direct relation between the hyperintensities caused by the edema and the hypointensities caused by the accumulation of iron.

  6. Methods for modeling and quantification in functional imaging by positron emissions tomography and magnetic resonance imaging

    International Nuclear Information System (INIS)

    Costes, Nicolas

    2017-01-01

    This report presents experiences and researches in the field of in vivo medical imaging by positron emission tomography (PET) and magnetic resonance imaging (MRI). In particular, advances in terms of reconstruction, quantification and modeling in PET are described. The validation of processing and analysis methods is supported by the creation of data by simulation of the imaging process in PET. The recent advances of combined PET/MRI clinical cameras, allowing simultaneous acquisition of molecular/metabolic PET information, and functional/structural MRI information opens the door to unique methodological innovations, exploiting spatial alignment and simultaneity of the PET and MRI signals. It will lead to an increase in accuracy and sensitivity in the measurement of biological phenomena. In this context, the developed projects address new methodological issues related to quantification, and to the respective contributions of MRI or PET information for a reciprocal improvement of the signals of the two modalities. They open perspectives for combined analysis of the two imaging techniques, allowing optimal use of synchronous, anatomical, molecular and functional information for brain imaging. These innovative concepts, as well as data correction and analysis methods, will be easily translated into other areas of investigation using combined PET/MRI. (author) [fr

  7. Magnetic resonance imaging detects placental hypoxia and acidosis in mouse models of perturbed pregnancies.

    Directory of Open Access Journals (Sweden)

    Gabriele Bobek

    Full Text Available Endothelial dysfunction as a result of dysregulation of anti-angiogenic molecules secreted by the placenta leads to the maternal hypertensive response characteristic of the pregnancy complication of preeclampsia. Structural abnormalities in the placenta have been proposed to result in altered placental perfusion, placental oxidative stress, cellular damage and inflammation and the release of anti-angiogenic compounds into the maternal circulation. The exact link between these factors is unclear. Here we show, using Magnetic Resonance Imaging as a tool to examine placental changes in mouse models of perturbed pregnancies, that T 2 contrast between distinct regions of the placenta is abolished at complete loss of blood flow. Alterations in T 2 (spin-spin or transverse relaxation times are explained as a consequence of hypoxia and acidosis within the tissue. Similar changes are observed in perturbed pregnancies, indicating that acidosis as well as hypoxia may be a feature of pregnancy complications such as preeclampsia and may play a prominent role in the signalling pathways that lead to the increased secretion of anti-angiogenic compounds.

  8. Glucosamine sulfate effect on the degenerated patellar cartilage: preliminary findings by pharmacokinetic magnetic resonance modeling

    Energy Technology Data Exchange (ETDEWEB)

    Marti-Bonmati, Luis [Dr Peset University Hospital, Radiology Department, Valencia (Spain); Hospital Quiron Valencia, Radiology Department, Valencia (Spain); Sanz-Requena, Roberto; Alberich-Bayarri, Angel [Hospital Quiron Valencia, Radiology Department, Valencia (Spain); Rodrigo, Jose Luis [Dr Peset University Hospital, Traumatology and Orthopedics Surgery Department, Valencia (Spain); Carot, Jose Miguel [Universidad Politecnica de Valencia, EIO Department, Valencia (Spain)

    2009-06-15

    Normal and degenerated cartilages have different magnetic resonance (MR) capillary permeability (K{sup trans}) and interstitial interchangeable volume (v{sub e}). Our hypothesis was that glucosamine sulfate treatment modifies these neovascularity abnormalities in osteoarthritis. Sixteen patients with patella degeneration, randomly distributed into glucosamine or control groups, underwent two 1.5-Tesla dynamic contrast-enhanced MR imaging studies (treatment initiation and after 6 months). The pain visual analog scale (VAS) and American Knee Society (AKS) score were used. A two-compartment pharmacokinetic model was used. Percentages of variations (postreatment-pretreatment/pretreatment) were compared (t-test for independent data). In the glucosamine group, pain and functional outcomes statistically improved (VAS: 7.3 {+-} 1.1 to 3.6 {+-} 1.3, p < 0.001; AKS: 18.6 {+-} 6.9 to 42.9 {+-} 2.7, p < 0.01). Glucosamine significantly increased K{sup trans} at 6 months (-54.4 {+-} 21.2% vs 126.7 {+-} 56.9%, p < 0.001, control vs glucosamine). In conclusion, glucosamine sulfate decreases pain while improving functional outcome in patients with cartilage degeneration. Glucosamine sulfate increases K{sup trans}, allowing its proposal as a surrogate imaging biomarker after 6 months of treatment. (orig.)

  9. Modelling of a diode laser with a resonant grating of quantum wells and an external mirror

    International Nuclear Information System (INIS)

    Vysotskii, D V; Elkin, N N; Napartovich, A P; Kozlovskii, Vladimir I; Lavrushin, B M

    2011-01-01

    A three-dimensional numerical model of a diode laser with a resonant grating of quantum wells (QWs) and an external mirror is developed and used to calculate diode laser pulses that are long compared to the time of reaching a stationary regime and are short enough to neglect heating of the medium. The consistent solutions of the Helmholtz field equation and the system of diffusion equations for inversion in each QW are found. A source of charge carriers can be both an electron beam and a pump laser beam. The calculations yielded the longitudinal and radial profiles of the generated field, as well as its wavelength and power. The effective threshold pump current is determined. In the created iteration algorithm, the calculation time linearly increases with the number of QWs, which allows one to find the characteristics of lasers with a large number of QWs. The output powers and beam divergence angles of a cylindrical laser are calculated for different cavity lengths and pump spot radii. After calculating the fundamental mode characteristics, high-order modes were additionally calculated on the background of the frozen carrier distributions in the QW grating. It is shown that all the competing modes remain below the excitation threshold for the pump powers used in the experiment. The calculated and experimental data for the case of pumping by a nanosecond electron beam are qualitatively compared.

  10. Equivalent circuit method research of resonant magnetoelectric characteristic in magnetoelectric laminate composites using nonlinear magnetostrictive constitutive model

    International Nuclear Information System (INIS)

    Zhou, Hao-Miao; Li, Chao; Xuan, Li-Ming; Zhao, Ji-Xiang; Wei, Jing

    2011-01-01

    This paper analyzes the magnetoelectric (ME) response around the resonance frequency in the magnetostrictive/piezoelectric/magnetostrictive (MPM) magnetoelectric laminate composites. Following the equivalent circuit method and considering the mechanical loss, we select the nonlinear magnetostrictive constitutive model to present a novel explicit nonlinear expression for the resonant magnetoelectric (ME) coefficient of the magnetoelectric laminate composites. Compared with the experimental results, the predicted resonant ME coefficient of the explicit expression shows a good agreement both qualitatively and quantitatively. Also, when the electromechanical coupling factor of the piezoelectric material, k 31 p , is small, this explicit expression can be reduced to the existing model. On this basis, this paper considers and predicts the magnetoelectric conversion characteristics of the magnetoelectric laminate composites, calculates and analyzes the influences of the thickness ratio of magnetostrictive layer and piezoelectric material, bias magnetic field, and saturation magnetostrictive coefficient on the resonant ME coefficient. This research can provide a theoretical basis for the preparation of magnetoelectric devices with good magnetoelectric conversion characteristics, such as magnetoelectric sensors, energy harvesting transducers, microwave devices etc

  11. Development and experimental evaluation of theoretical models for ion cyclotron resonance frequency heating of tokamak plasmas

    International Nuclear Information System (INIS)

    Mantsinen, M.

    1999-01-01

    Heating with electromagnetic waves in the ion cyclotron range of frequencies (ICRF) is a well-established method for auxiliary heating of present-day tokamak plasmas and is envisaged as one of the main heating techniques for the International Thermonuclear Experimental Reactor (ITER) and future reactor plasmas. In order to predict the performance of ICRF heating in future machines, it is important to benchmark present theoretical modelling with experimental results on present tokamaks. This thesis reports on development and experimental evaluation of theoretical models for ICRF heating at the Joint European Torus (JET). Several ICRF physics effects and scenarios have been studied. Direct importance to the ITER is the theoretical analysis of ICRF heating experiments with deuterium-tritium (D-T) plasmas. These experiments clearly demonstrate the potential of ICRF heating for auxiliary heating of reactor plasmas. In particular, scenarios with potential for good bulk ion heating and enhanced D-T fusion reactivity have been identified. Good bulk ion heating is essential for reactor plasmas in order to obtain a high ion temperature and a high fusion reactivity. In JET good bulk ion heating with ICRF waves has been achieved in high-performance discharges by adding ICRF heating to neutral beam injection. In these experiments, as in other JET discharges where damping at higher harmonics of the ion cyclotron frequency takes place, so-called finite Larmor radius (FLR) effects play an important role. Due to FLR effects, the resonating ion velocity distribution function can have a strong influence on the power deposition. Evidence for this effect has been obtained from the third harmonic deuterium heating experiments. Because of FLR effects, the wave-particle interaction can also become weak at certain ion energies, which prevents resonating ions from reaching higher energies. When interacting with the wave, an ion receives not only a change in energy but also a change in

  12. Development and experimental evaluation of theoretical models for ion cyclotron resonance frequency heating of tokamak plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Mantsinen, M. [Helsinki Univ. of Technology, Espoo (Finland). Dept. of Technical Physics

    1999-06-01

    Heating with electromagnetic waves in the ion cyclotron range of frequencies (ICRF) is a well-established method for auxiliary heating of present-day tokamak plasmas and is envisaged as one of the main heating techniques for the International Thermonuclear Experimental Reactor (ITER) and future reactor plasmas. In order to predict the performance of ICRF heating in future machines, it is important to benchmark present theoretical modelling with experimental results on present tokamaks. This thesis reports on development and experimental evaluation of theoretical models for ICRF heating at the Joint European Torus (JET). Several ICRF physics effects and scenarios have been studied. Direct importance to the ITER is the theoretical analysis of ICRF heating experiments with deuterium-tritium (D-T) plasmas. These experiments clearly demonstrate the potential of ICRF heating for auxiliary heating of reactor plasmas. In particular, scenarios with potential for good bulk ion heating and enhanced D-T fusion reactivity have been identified. Good bulk ion heating is essential for reactor plasmas in order to obtain a high ion temperature and a high fusion reactivity. In JET good bulk ion heating with ICRF waves has been achieved in high-performance discharges by adding ICRF heating to neutral beam injection. In these experiments, as in other JET discharges where damping at higher harmonics of the ion cyclotron frequency takes place, so-called finite Larmor radius (FLR) effects play an important role. Due to FLR effects, the resonating ion velocity distribution function can have a strong influence on the power deposition. Evidence for this effect has been obtained from the third harmonic deuterium heating experiments. Because of FLR effects, the wave-particle interaction can also become weak at certain ion energies, which prevents resonating ions from reaching higher energies. When interacting with the wave, an ion receives not only a change in energy but also a change in

  13. Mathematical models for the diffusion magnetic resonance signal abnormality in patients with prion diseases

    Directory of Open Access Journals (Sweden)

    Matteo Figini

    2015-01-01

    Full Text Available In clinical practice signal hyperintensity in the cortex and/or in the striatum on magnetic resonance (MR diffusion-weighted images (DWIs is a marker of sporadic Creutzfeldt–Jakob Disease (sCJD. MR diagnostic accuracy is greater than 90%, but the biophysical mechanisms underpinning the signal abnormality are unknown. The aim of this prospective study is to combine an advanced DWI protocol with new mathematical models of the microstructural changes occurring in prion disease patients to investigate the cause of MR signal alterations. This underpins the later development of more sensitive and specific image-based biomarkers. DWI data with a wide a range of echo times and diffusion weightings were acquired in 15 patients with suspected diagnosis of prion disease and in 4 healthy age-matched subjects. Clinical diagnosis of sCJD was made in nine patients, genetic CJD in one, rapidly progressive encephalopathy in three, and Gerstmann–Sträussler–Scheinker syndrome in two. Data were analysed with two bi-compartment models that represent different hypotheses about the histopathological alterations responsible for the DWI signal hyperintensity. A ROI-based analysis was performed in 13 grey matter areas located in affected and apparently unaffected regions from patients and healthy subjects. We provide for the first time non-invasive estimate of the restricted compartment radius, designed to reflect vacuole size, which is a key discriminator of sCJD subtypes. The estimated vacuole size in DWI hyperintense cortex was in the range between 3 and 10 µm that is compatible with neuropathology measurements. In DWI hyperintense grey matter of sCJD patients the two bi-compartment models outperform the classic mono-exponential ADC model. Both new models show that T2 relaxation times significantly increase, fast and slow diffusivities reduce, and the fraction of the compartment with slow/restricted diffusion increases compared to unaffected grey matter of

  14. Modeling, Fabrication and Characterization of Scalable Electroless Gold Plated Nanostructures for Enhanced Surface Plasmon Resonance

    Science.gov (United States)

    Jang, Gyoung Gug

    The scientific and industrial demand for controllable thin gold (Au) film and Au nanostructures is increasing in many fields including opto-electronics, photovoltaics, MEMS devices, diagnostics, bio-molecular sensors, spectro-/microscopic surfaces and probes. In this study, a novel continuous flow electroless (CF-EL) Au plating method is developed to fabricate uniform Au thin films in ambient condition. The enhanced local mass transfer rate and continuous deposition resulting from CF-EL plating improved physical uniformity of deposited Au films and thermally transformed nanoparticles (NPs). Au films and NPs exhibited improved optical photoluminescence (PL) and surface plasmon resonance (SPR), respectively, relative to batch immersion EL (BI-EL) plating. Suggested mass transfer models of Au mole deposition are consistent with optical feature of CF-EL and BI-EL films. The prototype CF-EL plating system is upgraded an automated scalable CF-EL plating system with real-time transmission UV-vis (T-UV) spectroscopy which provides the advantage of CF-EL plating, such as more uniform surface morphology, and overcomes the disadvantages of conventional EL plating, such as no continuous process and low deposition rate, using continuous process and controllable deposition rate. Throughout this work, dynamic morphological and chemical transitions during redox-driven self-assembly of Ag and Au film on silica surfaces under kinetic and equilibrium conditions are distinguished by correlating real-time T-UV spectroscopy with X-ray photoelectron spectroscopy (XPS) and scanning electron microscopy (SEM) measurements. The characterization suggests that four previously unrecognized time-dependent physicochemical regimes occur during consecutive EL deposition of silver (Ag) and Au onto tin-sensitized silica surfaces: self-limiting Ag activation; transitory Ag NP formation; transitional Au-Ag alloy formation during galvanic replacement of Ag by Au; and uniform morphology formation under

  15. Diffusion tensor magnetic resonance imaging driven growth modeling for radiotherapy target definition in glioblastoma.

    Science.gov (United States)

    Jensen, Morten B; Guldberg, Trine L; Harbøll, Anja; Lukacova, Slávka; Kallehauge, Jesper F

    2017-11-01

    The clinical target volume (CTV) in radiotherapy is routinely based on gadolinium contrast enhanced T1 weighted (T1w + Gd) and T2 weighted fluid attenuated inversion recovery (T2w FLAIR) magnetic resonance imaging (MRI) sequences which have been shown to over- or underestimate the microscopic tumor cell spread. Gliomas favor spread along the white matter fiber tracts. Tumor growth models incorporating the MRI diffusion tensors (DTI) allow to account more consistently for the glioma growth. The aim of the study was to investigate the potential of a DTI driven growth model to improve target definition in glioblastoma (GBM). Eleven GBM patients were scanned using T1w, T2w FLAIR, T1w + Gd and DTI. The brain was segmented into white matter, gray matter and cerebrospinal fluid. The Fisher-Kolmogorov growth model was used assuming uniform proliferation and a difference in white and gray matter diffusion of a ratio of 10. The tensor directionality was tested using an anisotropy weighting parameter set to zero (γ0) and twenty (γ20). The volumetric comparison was performed using Hausdorff distance, Dice similarity coefficient (DSC) and surface area. The median of the standard CTV (CTVstandard) was 180 cm 3 . The median surface area of CTVstandard was 211 cm 2 . The median surface area of respective CTV γ0 and CTV γ20 significantly increased to 338 and 376 cm 2 , respectively. The Hausdorff distance was greater than zero and significantly increased for both CTV γ0 and CTV γ20 with respective median of 18.7 and 25.2 mm. The DSC for both CTV γ0 and CTV γ20 were significantly below one with respective median of 0.74 and 0.72, which means that 74 and 72% of CTVstandard were included in CTV γ0 and CTV γ20, respectively. DTI driven growth models result in CTVs with a significantly increased surface area, a significantly increased Hausdorff distance and decreased overlap between the standard and model derived volume.

  16. Model-based T{sub 2} relaxometry using undersampled magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Sumpf, Tilman

    2013-11-01

    T{sub 2} relaxometry refers to the quantitative determination of spin-spin relaxation times in magnetic resonance imaging (MRI). Particularly in clinical diagnostics, the method provides important information about tissue structures and respective pathologic alterations. Unfortunately, it also requires comparatively long measurement times which preclude widespread practical applications. To overcome such limitations, a so-called model-based reconstruction concept has recently been proposed. The method allows for the estimation of spin-density and T{sub 2} parameter maps from only a fraction of the usually required data. So far, promising results have been reported for a radial data acquisition scheme. However, due to technical reasons, radial imaging is only available on a very limited number of MRI systems. The present work deals with the realization and evaluation of different model-based T{sub 2} reconstruction methods that are applicable for the most widely available Cartesian (rectilinear) acquisition scheme. The initial implementation is based on the conventional assumption of a mono-exponential T{sub 2} signal decay. A suitable sampling scheme as well as an automatic scaling procedure are developed, which remove the necessity of manual parameter tuning. As demonstrated for human brain MRI data, the technique allows for a more than 5-fold acceleration of the underlying data acquisition. Furthermore, general limitations and specific error sources are identified and suitable simulation programs are developed for their detailed analysis. In addition to phase variations in image space, the simulations reveal truncation effects as a relevant cause of reconstruction artifacts. To reduce the latter, an alternative model formulation is developed and tested. For noise-free simulated data, the method yields an almost complete suppression of associated artifacts. Residual problems in the reconstruction of experimental MRI data point to the predominant influence of other

  17. Exact calculation of the time convolutionless master equation generator: Application to the nonequilibrium resonant level model

    Energy Technology Data Exchange (ETDEWEB)

    Kidon, Lyran [School of Chemistry, The Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978 (Israel); The Sackler Center for Computational Molecular and Materials Science, Tel Aviv University, Tel Aviv 69978 (Israel); Wilner, Eli Y. [School of Physics and Astronomy, The Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978 (Israel); Rabani, Eran [The Sackler Center for Computational Molecular and Materials Science, Tel Aviv University, Tel Aviv 69978 (Israel); Department of Chemistry, University of California and Lawrence Berkeley National Laboratory, Berkeley California 94720-1460 (United States)

    2015-12-21

    The generalized quantum master equation provides a powerful tool to describe the dynamics in quantum impurity models driven away from equilibrium. Two complementary approaches, one based on Nakajima–Zwanzig–Mori time-convolution (TC) and the other on the Tokuyama–Mori time-convolutionless (TCL) formulations provide a starting point to describe the time-evolution of the reduced density matrix. A key in both approaches is to obtain the so called “memory kernel” or “generator,” going beyond second or fourth order perturbation techniques. While numerically converged techniques are available for the TC memory kernel, the canonical approach to obtain the TCL generator is based on inverting a super-operator in the full Hilbert space, which is difficult to perform and thus, nearly all applications of the TCL approach rely on a perturbative scheme of some sort. Here, the TCL generator is expressed using a reduced system propagator which can be obtained from system observables alone and requires the calculation of super-operators and their inverse in the reduced Hilbert space rather than the full one. This makes the formulation amenable to quantum impurity solvers or to diagrammatic techniques, such as the nonequilibrium Green’s function. We implement the TCL approach for the resonant level model driven away from equilibrium and compare the time scales for the decay of the generator with that of the memory kernel in the TC approach. Furthermore, the effects of temperature, source-drain bias, and gate potential on the TCL/TC generators are discussed.

  18. Cavity-enhanced surface-plasmon resonance sensing: Modeling and performance

    Czech Academy of Sciences Publication Activity Database

    Giorgini, A.; Avino, S.; Malara, P.; Zullo, R.; Gaglio, G.; Homola, Jiří; De Natale, P.

    2014-01-01

    Roč. 25, č. 1 (2014), 015205 ISSN 0957-0233 Institutional support: RVO:67985882 Keywords : optical resonators * optical sensors * cavity ring-down spectroscopy Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 1.433, year: 2014

  19. Cultural Resources Survey of Mobile Harbor, Alabama.

    Science.gov (United States)

    1983-01-01

    improvement from the point of view of supply and communication with other European settlements, since it cut the lightering distance to the capital in half...order to cut the costs of building (Bathe 1978:08.00-02; Millar 1978:15-29). 32 6e The sharing of ship builders, the borrowing of vessel lines and the... Eslava Street Mobile. Burned to water’s edge during overhaul. Notes: Served as HINGHAM in Boston Harbor; served as ORIENT in Long Island Sound. Operated

  20. Bluff evolution along coastal drumlins: Boston Harbor Islands, Massachusetts

    Science.gov (United States)

    Himmelstoss, E.A.; FitzGerald, D.M.; Rosen, P.S.; Allen, J.R.

    2006-01-01

    A series of partially drowned drumlins forms the backbone of the inner islands within Boston Harbor. The shoreline of these rounded glacial deposits is composed of actively retreating bluffs formed by continual wave attack. Comparisons of bluffs reveal variability in their height and lateral extent, as well as in the dominant mechanism causing their retreat. Two processes are responsible for bluff erosion and yield distinct bluff morphologies: (1) wave attack undercuts the bluff and causes episodic slumping, yielding planar bluff slopes, and (2) subaerial processes such as rainfall create irregular slopes characterized by rills and gullies. We propose a model of drumlin bluff evolution that is based on processes of erosion and physical characteristics such as bluff height, slope morphology, and the orientation of the bluff with respect to the long axis of the drumlin and its topographic crest. The four phases of drumlin bluff evolution consist of (1) initial formation of bluff, with retreat dominated by wave notching and slumping processes; (2) rill and gully development as bluff heights exceed 10 m and slumped sediment at bluff base inhibits wave attack; (3) return of wave notching and slumping as bluff heights decrease; and (4) final development of boulder retreat lag as last remnants of drumlin are eroded by wave action. These phases capture the important physical processes of drumlin evolution in Boston Harbor and could apply to other eroding coastal drumlin deposits.

  1. Modeling of Plutonium Ionization Probabilities for Use in Nuclear Forensic Analysis by Resonance Ionization Mass Spectrometry

    Science.gov (United States)

    2016-12-01

    masses collide, they form a supercritical mass . Criticality refers to the neutron population within the system. A critical system is one that can...Spectrometry, no. 242, pp. 161–168, 2005. [9] S. Raeder, “Trace analysis of actinides in the environment by means of resonance ionization mass ...first ionization potential of actinide elements by resonance ionization mass spectrometry.” Spectrochimica Acta part B: Atomic Spectroscopy. vol. 52

  2. 77 FR 50916 - Safety Zone; Boston Harbor's Rock Removal Project, Boston Inner Harbor, Boston, MA

    Science.gov (United States)

    2012-08-23

    ... operation on the navigable waters of Boston Inner Harbor, in the main ship channel near Castle Island. This... operations in support of the U.S. Army Corps of Engineers rock removal project. Entering into, transiting... before the start date of the project. The U.S. Army Corps of Engineers also discussed the rock removal...

  3. Inert two-Higgs-doublet model strongly coupled to a non-Abelian vector resonance

    Science.gov (United States)

    Rojas-Abatte, Felipe; Mora, Maria Luisa; Urbina, Jose; Zerwekh, Alfonso R.

    2017-11-01

    We study the possibility of a dark matter candidate having its origin in an extended Higgs sector which, at least partially, is related to a new strongly interacting sector. More concretely, we consider an i2HDM (i.e., a Type-I two Higgs doublet model supplemented with a Z2 under which the nonstandard scalar doublet is odd) based on the gauge group S U (2 )1×S U (2 )2×U (1 )Y . We assume that one of the scalar doublets and the standard fermion transform nontrivially under S U (2 )1 while the second doublet transforms under S U (2 )2. Our main hypothesis is that standard sector is weakly coupled while the gauge interactions associated to the second group is characterized by a large coupling constant. We explore the consequences of this construction for the phenomenology of the dark matter candidate and we show that the presence of the new vector resonance reduces the relic density saturation region, compared to the usual i2DHM, in the high dark matter mass range. In the collider side, we argue that the mono-Z production is the channel which offers the best chances to manifest the presence of the new vector field. We study the departures from the usual i2HDM predictions and show that the discovery of the heavy vector at the LHC is challenging even in the mono-Z channel since the typical cross sections are of the order of 10-2 fb .

  4. Modeling and Simulation of a Resonant-Cavity-Enhanced InGaAs/GaAs Quantum Dot Photodetector

    Directory of Open Access Journals (Sweden)

    W. W. Wang

    2015-01-01

    Full Text Available We simulated and analyzed a resonant-cavity-enhancedd InGaAs/GaAs quantum dot n-i-n photodiode using Crosslight Apsys package. The resonant cavity has a distributed Bragg reflector (DBR at one side. Comparing with the conventional photodetectors, the resonant-cavity-enhanced photodiode (RCE-PD showed higher detection efficiency, faster response speed, and better wavelength selectivity and spatial orientation selectivity. Our simulation results also showed that when an AlAs layer is inserted into the device structure as a blocking layer, ultralow dark current can be achieved, with dark current densities 0.0034 A/cm at 0 V and 0.026 A/cm at a reverse bias of 2 V. We discussed the mechanism producing the photocurrent at various reverse bias. A high quantum efficiency of 87.9% was achieved at resonant wavelength of 1030 nm with a FWHM of about 3 nm. We also simulated InAs QD RCE-PD to compare with InGaAs QD. At last, the photocapacitance characteristic of the model has been discussed under different frequencies.

  5. A quantitative modeling of the contributions of localized surface plasmon resonance and interband transitions to absorbance of gold nanoparticles

    International Nuclear Information System (INIS)

    Zhu, S.; Chen, T. P.; Liu, Y. C.; Liu, Y.; Fung, S.

    2012-01-01

    A quantitative modeling of the contributions of localized surface plasmon resonance (LSPR) and interband transitions to absorbance of gold nanoparticles has been achieved based on Lorentz–Drude dispersion function and Maxwell-Garnett effective medium approximation. The contributions are well modeled with three Lorentz oscillators. Influence of the structural properties of the gold nanoparticles on the LSPR and interband transitions has been examined. In addition, the dielectric function of the gold nanoparticles has been extracted from the modeling to absorbance, and it is found to be consistent with the result yielded from the spectroscopic ellipsometric analysis.

  6. Three-dimensional modeling of plasma edge transport and divertor fluxes during application of resonant magnetic perturbations on ITER

    Czech Academy of Sciences Publication Activity Database

    Schmitz, O.; Becoulet, M.; Cahyna, Pavel; Evans, T.E.; Feng, Y.; Frerichs, H.; Loarte, A.; Pitts, R.A.; Reiser, D.; Fenstermacher, M.E.; Harting, D.; Kirschner, A.; Kukushkin, A.; Lunt, T.; Saibene, G.; Reiter, D.; Samm, U.; Wiesen, S.

    2016-01-01

    Roč. 56, č. 6 (2016), č. článku 066008. ISSN 0029-5515 Institutional support: RVO:61389021 Keywords : resonant magnetic perturbations * plasma edge physics * 3D modeling * neutral particle physics * ITER * divertor heat and particle loads * ELM control Subject RIV: BL - Plasma and Gas Discharge Physics OBOR OECD: Fluids and plasma physics (including surface physics) Impact factor: 3.307, year: 2016 http://iopscience.iop.org/article/10.1088/0029-5515/56/6/066008/meta

  7. The Vlasov equation with strong magnetic field and oscillating electric field as a model for isotop resonant separation

    Directory of Open Access Journals (Sweden)

    Emmanuel Frenod

    2002-01-01

    Full Text Available We study the qualitative behavior of solutions to the Vlasov equation with strong external magnetic field and oscillating electric field. This model is relevant to the understanding of isotop resonant separation. We show that the effective equation is a kinetic equation with a memory term. This memory term involves a pseudo-differential operator whose kernel is characterized by an integral equation involving Bessel functions. The kernel is explicitly given in some particular cases.

  8. Two-body molecular model for resonances in heavy ion reactions

    International Nuclear Information System (INIS)

    Abe, Y.

    1978-01-01

    It is necessary to develop qualitative arguments on resonance mechanisms, which will give an overview on occurrences of resonances in heavy ion reactions, and further to identify typical examples of nuclear molecules among existing experimental data. In section 2, qualitative arguments on resonance mechanisms are given by exemplifying the 12 C + 16 O system with the 3 - excitation of the 16 O nucleus. In section 3 a simple formulation in the coupled channel framework is given. Resonances in the 12 C - 16 O system, which has been observed well above the Coulomb barrier, are investigated in section 4. In section 5 an old, but not yet solved problem on resonances in the 12 C + 12 C system which have been observed at sub-Coulomb energies, is taken up along the nuclear molecular picture. Further discussions are given on a role of the 20 Ne-α channel along the present simple qualitative picture given in section 2, which can be extended to rearrangement channels. (Auth.)

  9. Magnetic resonance in spin glasses, superconductivity of thin aluminum films and models for transport properties of one dimensional systems

    International Nuclear Information System (INIS)

    Elliott, J.H.

    1983-01-01

    This thesis reports on three separate investigations in solid state physics. The first is electron paramagnetic resonance in the spin glass Ag:Mn. EPR measurements were performed at two resonance frequencies, concentrating on temperatures above the glass transition temperature. The measured linewidth appears to diverge at T/sub g/ for low resonance frequencies. These results will be compared with recently proposed phenomenological and microscopic theories. The second topic reported in this thesis is the superconducting transition of thin aluminum films. These films were investigated as a function of grain size and thickness. The transition temperature was enhanced over the bulk value, in agreement with many previous investigations of granular aluminum. The third topic reported in this thesis is an extension of the variable rate hopping theory applied in one dimension to N-ME-Qn(TCNQ) 2 . This model is a classical one used to explain both the dc and ac electrical conductivity of organic conductors. The temperature dependence of the model does not agree with experiment at low temperatures. Tunneling has been added to the hopping. This increases the conductivity at low temperatures, and results in excellent agreement with the experimental conductivity over the measured temperature range. The model also predicts that the frequency dependence of the conductivity varies as ω/sup .5/ at low frequencies. This long time tail prediction agrees with the measured dielectric constant of N-Me-iso-Qn(TCNQ) 2

  10. a{sub 0}(980) as a dynamically generated resonance in the extended Linear Sigma Model

    Energy Technology Data Exchange (ETDEWEB)

    Wolkanowski-Gans, Thomas; Giacosa, Francesco [Goethe-Universitaet Frankfurt am Main (Germany)

    2014-07-01

    We study basic properties of scalar hadronic resonances within the so-called extended linear sigma model (eLSM), which is an effective model of QCD based on chiral symmetry and dilatation invariance. In particular, we focus on the mass and decay width of the isovector state a{sub 0}(1450) and perform a numerical study of the propagator pole(s) on the unphysical Riemann sheets. Here, the a{sub 0}(1450) is understood as a seed state explicitly included in the eLSM - this is in fact not true for the corresponding resonance below 1 GeV, the a{sub 0}(980), which is sometimes interpreted as a kaonic (i.e., dynamically generated) bound state. In our work we want to clarify if the yet not included a{sub 0}(980) can be found as a propagator pole generated by hadronic loop contributions. From such an investigation one could learn more about the general dependence of the eLSM - and effective field models in general - on strongly coupled hadronic intermediate states, possibly giving new insight into the low-energy regime, scalar resonances and both its theoretical description and physical interpretation.

  11. Modelling fragmentations of amino-acids after resonant electron attachment: quantum evidence of possible direct -OH detachment

    Energy Technology Data Exchange (ETDEWEB)

    Panosetti, C.; Sebastianelli, F.; Gianturco, F.A. [Department of Chemistry and CNISM, University of Rome -La Sapienza-, Roma (Italy); Baccarelli, I. [CASPUR, Supercomputing Consortium for University and Research, Roma (Italy)

    2010-10-15

    We investigate some aspects of the radiation damage mechanisms in biomolecules, focusing on the modelling of resonant fragmentation caused by the attachment of low-energy electrons (LEEs) initially ejected by biological tissues when exposed to ionizing radiation. Scattering equations are formulated within a symmetry-adapted, single-center expansion of both continuum and bound electrons, and the interaction forces are obtained from a combination of ab initio calculations and a nonempirical model of exchange and correlation effects developed in our group. We present total elastic scattering cross-sections and resonance features obtained for the equilibrium geometries of glycine, alanine, proline and valine. Our results at those geometries of the target molecules are briefly shown to qualitatively explain some of the fragmentation patterns obtained in experiments. We further carry out a one-dimensional (1D) modeling for the dynamics of intramolecular energy transfers mediated by the vibrational activation of selected bonds: our calculations indicate that resonant electron attachment to glycine can trigger direct, dissociative evolution of the complex into (Gly-OH)- and -OH losses, while they also find that the same process does not occur via a direct, 1D dissociative path in the larger amino acids of the present study. (authors)

  12. Vibration-based structural health monitoring of harbor caisson structure

    Science.gov (United States)

    Lee, So-Young; Lee, So-Ra; Kim, Jeong-Tae

    2011-04-01

    This study presents vibration-based structural health monitoring method in foundation-structure interface of harbor caisson structure. In order to achieve the objective, the following approaches are implemented. Firstly, vibration-based response analysis method is selected and structural health monitoring (SHM) technique is designed for harbor caisson structure. Secondly, the performance of designed SHM technique for harbor structure is examined by FE analysis. Finally, the applicability of designed SHM technique for harbor structure is evaluated by dynamic tests on a lab-scaled caisson structure.

  13. Cavity-enhanced surface-plasmon resonance sensing: modeling and performance

    International Nuclear Information System (INIS)

    Giorgini, A; Avino, S; Malara, P; Zullo, R; Gagliardi, G; Homola, J; De Natale, P

    2014-01-01

    We investigate the performance of a surface-plasmon-resonance refractive-index (RI) sensor based on an optical resonator. The resonator transforms RI changes of liquid samples, interacting with the surface plasmon excited by near-infrared light, into a variation of the intra-cavity optical loss. Cavity ring-down measurements are provided as a proof of concept of RI sensing on calibrated mixtures. A characterization of the overall sensor response and noise features as well as a discussion on possible improvements is carried out. A reproducibility analysis shows that a resolution of 10 −7 –10 −8  RIU is within reach over observation times of 1–30 s. The ultimate resolution is set only by intrinsic noise features of the cavity-based method, pointing to a potential limit below 10 −10  RIU/√Hz. (paper)

  14. Modeling and simulation of two-step resonance ionization processes using CW and pulsed lasers

    CERN Document Server

    de Groote, Ruben; Flanagan, Kieran

    This thesis derives and discusses equations that describe the evolution of atomic systems subjected to two monochromatic and coherent radiation fields and treats both continuous and temporally pulsed irradiation. This theoretical description is de- veloped mainly to understand the influence of the photon field intensities on experimental ionization spectra. The primary ap- plication of this theoretical framework is on methods that rely on resonant laser excitation and non-resonant laser ionization to extract information on the hyperfine structure of atomic systems. In particular, qualitative and quantitative discussions on the laser-related changes in hyperfine splitting extracted from ion- ization spectra are presented. Also, a method for increasing the resolution of resonance ionization techniques (potentially up un- til the natural linewidth of the electronic transitions) is discussed and theoretically justified. Both topics are illustrated with exper- imental data.

  15. Routine magnetic resonance imaging for idiopathic olfactory loss: a modeling-based economic evaluation.

    Science.gov (United States)

    Rudmik, Luke; Smith, Kristine A; Soler, Zachary M; Schlosser, Rodney J; Smith, Timothy L

    2014-10-01

    Idiopathic olfactory loss is a common clinical scenario encountered by otolaryngologists. While trying to allocate limited health care resources appropriately, the decision to obtain a magnetic resonance imaging (MRI) scan to investigate for a rare intracranial abnormality can be difficult. To evaluate the cost-effectiveness of ordering routine MRI in patients with idiopathic olfactory loss. We performed a modeling-based economic evaluation with a time horizon of less than 1 year. Patients included in the analysis had idiopathic olfactory loss defined by no preceding viral illness or head trauma and negative findings of a physical examination and nasal endoscopy. Routine MRI vs no-imaging strategies. We developed a decision tree economic model from the societal perspective. Effectiveness, probability, and cost data were obtained from the published literature. Litigation rates and costs related to a missed diagnosis were obtained from the Physicians Insurers Association of America. A univariate threshold analysis and multivariate probabilistic sensitivity analysis were performed to quantify the degree of certainty in the economic conclusion of the reference case. The comparative groups included those who underwent routine MRI of the brain with contrast alone and those who underwent no brain imaging. The primary outcome was the cost per correct diagnosis of idiopathic olfactory loss. The mean (SD) cost for the MRI strategy totaled $2400.00 ($1717.54) and was effective 100% of the time, whereas the mean (SD) cost for the no-imaging strategy totaled $86.61 ($107.40) and was effective 98% of the time. The incremental cost-effectiveness ratio for the MRI strategy compared with the no-imaging strategy was $115 669.50, which is higher than most acceptable willingness-to-pay thresholds. The threshold analysis demonstrated that when the probability of having a treatable intracranial disease process reached 7.9%, the incremental cost-effectiveness ratio for MRI vs no

  16. Liquid-Liquid Phase Separation in Model Nuclear Waste Glasses: A Solid-State Double-Resonance NMR Study

    Energy Technology Data Exchange (ETDEWEB)

    Martineau, Ch.; Michaelis, V.K.; Kroeker, S. [Univ Manitoba, Dept Chem, Winnipeg, MB R3T 2N2 (Canada); Schuller, S. [CEA Valrho Marcoule, LDMC, SECM, DTCD, DEN, F-30207 Bagnols Sur Ceze (France)

    2010-07-01

    Double-resonance nuclear magnetic resonance (NMR) techniques are used in addition to single-resonance NMR experiments to probe the degree of mixing between network-forming cations Si and B, along with the modifier cations Cs{sup +} and Na{sup +} in two molybdenum-bearing model nuclear waste glasses. The double-resonance experiments involving {sup 29}Si in natural abundance are made possible by the implementation of a CPMG pulse-train during the acquisition period of the usual REDOR experiments. For the glass with lower Mo content, the NMR results show a high degree of Si-B mixing, as well as an homogeneous distribution of the cations within the borosilicate network, characteristic of a non-phase-separated glass. For the higher-Mo glass, a decrease of B-Si(Q{sup 4}) mixing is observed, indicating phase separation. {sup 23}Na and {sup 133}Cs NMR results show that although the Cs{sup +} cations, which do not seem to be influenced by the molybdenum content, are spread within the borate network, there is a clustering of the Na{sup +} cations, very likely around the molybdate units. The segregation of a Mo-rich region with Na{sup +} cations appears to shift the bulk borosilicate glass composition toward the metastable liquid liquid immiscibility region and induce additional phase separation. Although no crystallization is observed in the present case, this liquid liquid phase separation is likely to be the first stage of crystallization that can occur at higher Mo loadings or be driven by heat treatment. From this study emerges a consistent picture of the nature and extent of such phase separation phenomena in Mo-bearing glasses, and demonstrates the potential of double-resonance NMR methods for the investigation of phase separation in amorphous materials. (authors)

  17. Modeling of ICRH H-minorit driven n = 1 Resonant Modes in JET

    International Nuclear Information System (INIS)

    Gorelenkov, N.N.; Mantsinen, M.J.; Sharapov, S.E.; Cheng, C.Z.

    2003-01-01

    A nonperturbative code NOVA-KN (Kinetic Nonperturbative) has been developed to account for finite orbit width (FOW) effects in nonperturbative resonant modes such as the low-frequency MHD modes observed in the Joint European Torus (JET). The NOVA-KN code was used to show that the resonant modes with frequencies in the observed frequency range are ones having the characteristic toroidal precession frequency of H-minority ions. Results are similar to previous theoretical studies of fishbone instabilities, which were found to exist at characteristic precession frequencies of hot ions

  18. Giant dipole resonances in hot nuclear matter in the model of self-relaxing mean field

    International Nuclear Information System (INIS)

    Okolowicz, J.; Ploszajczak, M.; Drozdz, S.; Caurier, E.

    1989-01-01

    The extended time-dependent Hartree-Fock approach is applied for the description of the isovector giant dipole resonance in 40 Ca at finite temperatures. The thermalization process is described using the relaxation-time ansatz for the collision integral. Strong inhibition of the giant-dipole-resonance γ-decay is found due to the fast vaporization of the nuclear surface for thermal excitation energies above E * /A ≅ 4.5 MeV. This pre-equilibrium emission of particles in the vapor phase is associated with the radial expansion of nucleus and with the vanishing particle binding energies mainly for protons. (orig.)

  19. New Constraints on Gliese 876—Exemplar of Mean-motion Resonance

    Science.gov (United States)

    Millholland, Sarah; Laughlin, Gregory; Teske, Johanna; Butler, R. Paul; Burt, Jennifer; Holden, Bradford; Vogt, Steven; Crane, Jeffrey; Shectman, Stephen; Thompson, Ian

    2018-03-01

    Gliese 876 harbors one of the most dynamically rich and well-studied exoplanetary systems. The nearby M4V dwarf hosts four known planets, the outer three of which are trapped in a Laplace mean-motion resonance. A thorough characterization of the complex resonant perturbations exhibited by the orbiting planets, and the chaotic dynamics therein, is key to a complete picture of the system’s formation and evolutionary history. Here we present a reanalysis of the system using 6 yr of new radial velocity (RV) data from four instruments. These new data augment and more than double the size of the decades-long collection of existing velocity measurements. We provide updated estimates of the system parameters by employing a computationally efficient Wisdom–Holman N-body symplectic integrator, coupled with a Gaussian process (GP) regression model to account for correlated stellar noise. Experiments with synthetic RV data show that the dynamical characterization of the system can differ depending on whether a white-noise or correlated-noise model is adopted. Despite there being a region of stability for an additional planet in the resonant chain, we find no evidence for one. Our new parameter estimates place the system even deeper into resonance than previously thought and suggest that the system might be in a low-energy, quasi-regular double apsidal corotation resonance. This result and others will be used in a subsequent study on the primordial migration processes responsible for the formation of the resonant chain.

  20. Structural damage monitoring of harbor caissons with interlocking condition

    Energy Technology Data Exchange (ETDEWEB)

    Huynh, Thanh Canh; Lee, So Young; Nauyen, Khac Duy; Kim, Jeong Tae [Pukyong National Univ., Busan (Korea, Republic of)

    2012-12-15

    The objective of this study is to monitor the health status of harbor caissons which have potential foundation damage. To obtain the objective, the following approaches are performed. Firstly, a structural damage monitoring(SDM) method is designed for interlocked multiple caisson structures. The SDM method utilizes the change in modal strain energy to monitor the foundation damage in a target caisson unit. Secondly, a finite element model of a caisson system which consists of three caisson units is established to verify the feasibility of the proposed method. In the finite element simulation, the caisson units are constrained each other by shear key connections. The health status of the caisson system against various levels of foundation damage is monitored by measuring relative modal displacements between the adjacent caissons.

  1. Structural damage monitoring of harbor caissons with interlocking condition

    International Nuclear Information System (INIS)

    Huynh, Thanh Canh; Lee, So Young; Nauyen, Khac Duy; Kim, Jeong Tae

    2012-01-01

    The objective of this study is to monitor the health status of harbor caissons which have potential foundation damage. To obtain the objective, the following approaches are performed. Firstly, a structural damage monitoring(SDM) method is designed for interlocked multiple caisson structures. The SDM method utilizes the change in modal strain energy to monitor the foundation damage in a target caisson unit. Secondly, a finite element model of a caisson system which consists of three caisson units is established to verify the feasibility of the proposed method. In the finite element simulation, the caisson units are constrained each other by shear key connections. The health status of the caisson system against various levels of foundation damage is monitored by measuring relative modal displacements between the adjacent caissons

  2. Hazardous substances shipping at inland water harbors

    International Nuclear Information System (INIS)

    Benkovic, Z.

    2009-01-01

    Safety measures and regulations system covering the aspects of fire protection, professional and ecological safety are aimed to create a safe working environment, by detection and remedy of conditions that are potentially hazardous for the well-being of the employees or are leading to certain undesired events. Such unwanted incidents may result in different consequences: operating person's injury, environment pollution or material damage. This study attempts to illustrate the organization of work during hazardous matter loading and unloading at inland water harbors, based on legal provisions and decrees involving safety precautions, and in order to achieve constant enhancement of operating procedure, decreasing thereby the number of work-related injuries and various accidental situations. Fundamental precondition required to prevent possible accidents and to optimize general safety policy is to recognize and control any danger or potential hazard, as well as to be familiar with the legal provisions covering the inland waterway transport of harmful substances.(author)

  3. a First-Principles Model of Fermi Resonance in the Alkyl CH Stretch Region: Application to Hydronaphthalenes, Indanes, and Cyclohexane

    Science.gov (United States)

    Sibert, Edwin; Kidwell, Nathanael; Zwier, Timothy S.

    2014-06-01

    The infrared (IR) spectroscopy of the alkyl CH stretch region (2750-3000 cm-1) of a series of bicyclic hydrocarbons and free radicals has been studied under supersonic expansion cooling in the gas phase, and compared with a theoretical model that describes the local mode stretch-bend Fermi resonance interactions. The double resonance method of fluorescence-dip infrared (FDIR) spectroscopy was used on the stable molecules 1,2-dihydronaphthalene, 1,4-dihydronaphthalene, tetralin, indene, and indane using the S_0-S_1 origin transition as a monitor of transitions. Resonant ion-dip infrared (RIDIR) spectra were recorded for the trihydronaphthyl (THN) and inden-2-yl methyl (I2M) radicals. The previously developed model Hamiltonian [J. Chem. Phys. 138 064308 (2013)] incorporates cubic stretch-bend coupling with parameters obtained from density functional theory methods. Full dimensional calculations are compared to reduced dimensional Hamiltonian results in which anharmonic CH streches and CH_2 scissor modes are Fermi coupled. Excellent agreement between theoretical results is found. Scale factors of select terms in the reduced dimensional Hamiltonian, obtained by fitting the theoretical Hamiltonian predictions to the experimental spectra, are found to be similar to previous work. The resulting Hamiltonian predicts successfully all the major spectral features considered in this study. A simplified model is introduced in which the CH_2 groups are decoupled. This model enables the assignment of many of the spectral features. The model results are extended to describe the CH stretch spectrum of the chair and twist-boat conformers of cyclohexane. The chair conformer is used to illustrate the shortcomings of the CH_2 coupling model.

  4. Some resonances between Eastern thought and Integral Biomathics in the framework of the WLIMES formalism for modeling living systems.

    Science.gov (United States)

    Simeonov, Plamen L; Ehresmann, Andrée C

    2017-12-01

    Forty-two years ago, Capra published "The Tao of Physics" (Capra, 1975). In this book (page 17) he writes: "The exploration of the atomic and subatomic world in the twentieth century has …. necessitated a radical revision of many of our basic concepts" and that, unlike 'classical' physics, the sub-atomic and quantum "modern physics" shows resonances with Eastern thoughts and "leads us to a view of the world which is very similar to the views held by mystics of all ages and traditions." This article stresses an analogous situation in biology with respect to a new theoretical approach for studying living systems, Integral Biomathics (IB), which also exhibits some resonances with Eastern thought. Stepping on earlier research in cybernetics 1 and theoretical biology, 2 IB has been developed since 2011 by over 100 scientists from a number of disciplines who have been exploring a substantial set of theoretical frameworks. From that effort, the need for a robust core model utilizing advanced mathematics and computation adequate for understanding the behavior of organisms as dynamic wholes was identified. At this end, the authors of this article have proposed WLIMES (Ehresmann and Simeonov, 2012), a formal theory for modeling living systems integrating both the Memory Evolutive Systems (Ehresmann and Vanbremeersch, 2007) and the Wandering Logic Intelligence (Simeonov, 2002b). Its principles will be recalled here with respect to their resonances to Eastern thought. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Nonlinear Container Ship Model for the Study of Parametric Roll Resonance

    DEFF Research Database (Denmark)

    Holden, Christian; Galeazzi, Roberto; Rodríguez, Claudio

    2007-01-01

    Parametric roll is a critical phenomenon for ships, whose onset may cause roll oscillations up to 40, leading to very dangerous situations and possibly capsizing. Container ships have been shown to be particularly prone to parametric roll resonance when they are sailing in moderate to heavy head ...

  6. A schizophrenia rat model induced by early postnatal phencyclidine treatment and characterized by Magnetic Resonance Imaging

    DEFF Research Database (Denmark)

    Broberg, Brian V; Madsen, Kristoffer H; Plath, Niels

    2013-01-01

    administration of phencyclidine (PCP) induces schizophrenia-like symptoms in healthy volunteers and exacerbates symptoms in patients with schizophrenia. In this study, pharmacological Magnetic Resonance Imaging (phMRI) was used to evaluate if rats treated with 20mg/kg PCP on postnatal days 7, 9, and 11 (neo...

  7. A normalized model for the half-bridge series resonant converter

    Science.gov (United States)

    King, R.; Stuart, T. A.

    1981-01-01

    Closed-form steady-state equations are derived for the half-bridge series resonant converter with a rectified (dc) load. Normalized curves for various currents and voltages are then plotted as a function of the circuit parameters. Experimental results based on a 10-kHz converter are presented for comparison with the calculations.

  8. 33 CFR 80.1460 - Kahului Harbor, Maui, HI.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Kahului Harbor, Maui, HI. 80.1460 Section 80.1460 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Islands § 80.1460 Kahului Harbor, Maui, HI. A line drawn...

  9. 33 CFR 80.1450 - Nawiliwili Harbor, Kauai, HI.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Nawiliwili Harbor, Kauai, HI. 80.1450 Section 80.1450 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Islands § 80.1450 Nawiliwili Harbor, Kauai, HI...

  10. 33 CFR 110.238 - Apra Harbor, Guam.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Apra Harbor, Guam. 110.238 Section 110.238 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.238 Apra Harbor, Guam. (a) The anchorage grounds (Datum: WGS...

  11. 33 CFR 80.1470 - Kawaihae Harbor, Hawaii, HI.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Kawaihae Harbor, Hawaii, HI. 80.1470 Section 80.1470 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Islands § 80.1470 Kawaihae Harbor, Hawaii, HI...

  12. 33 CFR 80.1480 - Hilo Harbor, Hawaii, HI.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Hilo Harbor, Hawaii, HI. 80.1480 Section 80.1480 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Islands § 80.1480 Hilo Harbor, Hawaii, HI. A line drawn...

  13. 33 CFR 110.208 - Buffalo Harbor, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Buffalo Harbor, N.Y. 110.208 Section 110.208 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.208 Buffalo Harbor, N.Y. (a) The anchorage grounds—(1...

  14. 32 CFR 705.31 - USS Arizona Memorial, Pearl Harbor.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false USS Arizona Memorial, Pearl Harbor. 705.31... NAVY REGULATIONS AND OFFICIAL RECORDS PUBLIC AFFAIRS REGULATIONS § 705.31 USS Arizona Memorial, Pearl Harbor. (a) Limited space and the desirability of keeping the Memorial simple and dignified require the...

  15. 76 FR 50489 - Agency Information Collection Activities: Harbor Maintenance Fee

    Science.gov (United States)

    2011-08-15

    ... Activities: Harbor Maintenance Fee AGENCY: U.S. Customs and Border Protection, Department of Homeland... Fee (CBP Forms 349 and 350). This is a proposed extension of an information collection that was... Fee. OMB Number: 1651-0055. Form Number: CBP Forms 349 and 350. Abstract: The Harbor Maintenance Fee...

  16. Frequency Preference Response to Oscillatory Inputs in Two-dimensional Neural Models: A Geometric Approach to Subthreshold Amplitude and Phase Resonance.

    Science.gov (United States)

    Rotstein, Horacio G

    2014-01-01

    We investigate the dynamic mechanisms of generation of subthreshold and phase resonance in two-dimensional linear and linearized biophysical (conductance-based) models, and we extend our analysis to account for the effect of simple, but not necessarily weak, types of nonlinearities. Subthreshold resonance refers to the ability of neurons to exhibit a peak in their voltage amplitude response to oscillatory input currents at a preferred non-zero (resonant) frequency. Phase-resonance refers to the ability of neurons to exhibit a zero-phase (or zero-phase-shift) response to oscillatory input currents at a non-zero (phase-resonant) frequency. We adapt the classical phase-plane analysis approach to account for the dynamic effects of oscillatory inputs and develop a tool, the envelope-plane diagrams, that captures the role that conductances and time scales play in amplifying the voltage response at the resonant frequency band as compared to smaller and larger frequencies. We use envelope-plane diagrams in our analysis. We explain why the resonance phenomena do not necessarily arise from the presence of imaginary eigenvalues at rest, but rather they emerge from the interplay of the intrinsic and input time scales. We further explain why an increase in the time-scale separation causes an amplification of the voltage response in addition to shifting the resonant and phase-resonant frequencies. This is of fundamental importance for neural models since neurons typically exhibit a strong separation of time scales. We extend this approach to explain the effects of nonlinearities on both resonance and phase-resonance. We demonstrate that nonlinearities in the voltage equation cause amplifications of the voltage response and shifts in the resonant and phase-resonant frequencies that are not predicted by the corresponding linearized model. The differences between the nonlinear response and the linear prediction increase with increasing levels of the time scale separation between

  17. Through tissue imaging of a live breast cancer tumour model using handheld surface enhanced spatially offset resonance Raman spectroscopy (SESORRS).

    Science.gov (United States)

    Nicolson, Fay; Jamieson, Lauren E; Mabbott, Samuel; Plakas, Konstantinos; Shand, Neil C; Detty, Michael R; Graham, Duncan; Faulds, Karen

    2018-04-21

    In order to improve patient survival and reduce the amount of unnecessary and traumatic biopsies, non-invasive detection of cancerous tumours is of imperative and urgent need. Multicellular tumour spheroids (MTS) can be used as an ex vivo cancer tumour model, to model in vivo nanoparticle (NP) uptake by the enhanced permeability and retention (EPR) effect. Surface enhanced spatially offset Raman spectroscopy (SESORS) combines both surface enhanced Raman spectroscopy (SERS) and spatially offset Raman spectroscopy (SORS) to yield enhanced Raman signals at much greater sub-surface levels. By utilizing a reporter that has an electronic transition in resonance with the laser frequency, surface enhanced resonance Raman scattering (SERRS) yields even greater enhancement in Raman signal. Using a handheld SORS spectrometer with back scattering optics, we demonstrate the detection of live breast cancer 3D MTS containing SERRS active NPs through 15 mm of porcine tissue. False color 2D heat intensity maps were used to determine tumour model location. In addition, we demonstrate the tracking of SERRS-active NPs through porcine tissue to depths of up to 25 mm. This unprecedented performance is due to the use of red-shifted chalcogenpyrylium-based Raman reporters to demonstrate the novel technique of surface enhanced spatially offset resonance Raman spectroscopy (SESORRS) for the first time. Our results demonstrate a significant step forward in the ability to detect vibrational fingerprints from a tumour model at depth through tissue. Such an approach offers significant promise for the translation of NPs into clinical applications for non-invasive disease diagnostics based on this new chemical principle of measurement.

  18. Using collisions and resonances to tilting Uranus

    Science.gov (United States)

    Rogoszinski, Zeeve; Hamilton, Douglas

    2018-01-01

    Uranus’ large obliquity (98°) is widely thought to have occurred from a polar strike with an Earth sized object. Morbidelli et al. (2012) argue that two or more collisions are required in order to explain the prograde motion of Uranus’ satellites. These impactors could have been less massive by about a factor of ten, but multiple polar strikes are still improbable as even larger mass impactors would be needed for more equatorial collisions. Here we explore an alternative non-collisional model inspired by the explanation to Saturn’s significant tilt (27°). Ward and Hamilton (2004) & Hamilton and Ward (2004) argue that a secular resonance currently between Saturn’s spin axis and Neptune’s orbital pole is responsible for Saturn’s large obliquity. Unfortunately, Uranus’ axial precession frequency today is too long to match any of the current planets’ fundamental frequencies. Boué and Laskar (2010) explain that Uranus may have harbored an improbably large moon in the past which could have sped up the planet’s axial precession frequency enough to resonate with the regression of its own orbital pole. We explore another scenario which requires only the interactions between the giant planets.Thommes et al. (1999, 2002, 2003) argue that at least the cores of Uranus and Neptune were formed in between Jupiter and Saturn, as the density of the protoplanetary disk was greater there. If Neptune was scattered outward before Uranus, then a secular spin-orbit resonance between the two planets is possible. However, driving Uranus’ obliquity to near 90° with a resonance capture requires a timescale on the order of 100 Myr. If Neptune migrated out quicker or its orbital inclination was initially larger, then we find that the resulting resonance kick can tilt Uranus more than 40° in a reasonable timespan. This could replace one of the impactors required in the collisional scenario described by Morbidelli et al. (2012), but in most situations the effect of such a

  19. Toroidal modeling of plasma response and resonant magnetic perturbation field penetration

    Czech Academy of Sciences Publication Activity Database

    Liu, Y.Q.; Kirk, A.; Sun, Y.; Cahyna, Pavel; Chapman, I.T.; Denner, P.; Fishpool, G.; Garofalo, A.M.; Harrison, J.R.; Nardon, E.

    2012-01-01

    Roč. 54, č. 12 (2012), s. 124013-124013 ISSN 0741-3335 Institutional research plan: CEZ:AV0Z20430508 Keywords : tokamak * resonant magnetic perturbation * neoclassical toroidal viscosity Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 2.369, year: 2012 http://iopscience.iop.org/0741-3335/54/12/124013/pdf/0741-3335_54_12_124013.pdf

  20. Minipig Model of Huntington's Disease: H-1 Magnetic Resonance Spectroscopy of the Brain

    Czech Academy of Sciences Publication Activity Database

    Jozefovičová, M.; Herynek, V.; Jírů, F.; Dezortová, M.; Juhásová, Jana; Juhás, Štefan; Motlík, Jan; Hájek, M.

    2016-01-01

    Roč. 65, č. 1 (2016), s. 155-163 ISSN 0862-8408 R&D Projects: GA TA ČR(CZ) TA01011466; GA MŠk(CZ) 7F14308; GA MŠk ED2.1.00/03.0124 Institutional support: RVO:67985904 Keywords : Huntington´s disease * minipigs * magnetic resonance spectroscopy Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.461, year: 2016

  1. Numerical simulation of coherent resonance in a model network of Rulkov neurons

    Science.gov (United States)

    Andreev, Andrey V.; Runnova, Anastasia E.; Pisarchik, Alexander N.

    2018-04-01

    In this paper we study the spiking behaviour of a neuronal network consisting of Rulkov elements. We find that the regularity of this behaviour maximizes at a certain level of environment noise. This effect referred to as coherence resonance is demonstrated in a random complex network of Rulkov neurons. An external stimulus added to some of neurons excites them, and then activates other neurons in the network. The network coherence is also maximized at the certain stimulus amplitude.

  2. Modeling and analysis of harmonic resonance in a power electronics based AC power system

    DEFF Research Database (Denmark)

    Wang, Xiongfei; Blaabjerg, Frede; Chen, Zhe

    2013-01-01

    The dynamic interactions among the interconnected power converters may bring in harmonic resonance in a power electronics based power system. This paper addresses this issue in a power system dominated by multiple current- and voltage-controlled inverters with LCL- and LC-filters. The impedance...... stability criterion. To validate the theoretical analysis, the time domain simulations and experimental tests on a three-inverter-based system are presented....

  3. Mathematical modeling and calculation of forced resonant vibrations of composite electromechanical system

    OpenAIRE

    Ластівка, Іван Олексійович

    2014-01-01

    Resonant vibrations of composite electromechanical symmetric three-element system “metal plate - piezoceramic cylindrical panels” are considered. Forced vibrations are made under the influence of external alternating electric field, supplied to the electrodes of piezoceramic segments of cylindrical panels, previously polarized in the tangential direction.Based on the improved theory, such as the S.P. Timoshenko’s, the system of differential equations of forced vibrations of the system, taking...

  4. 33 CFR 165.904 - Lake Michigan at Chicago Harbor & Burnham Park Harbor-Safety and Security Zone.

    Science.gov (United States)

    2010-07-01

    ... & Burnham Park Harbor-Safety and Security Zone. 165.904 Section 165.904 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY REGULATED NAVIGATION... Guard District § 165.904 Lake Michigan at Chicago Harbor & Burnham Park Harbor—Safety and Security Zone...

  5. 77 FR 59551 - Safety Zone, Changes to Original Rule; Boston Harbor's Rock Removal Project, Boston Inner Harbor...

    Science.gov (United States)

    2012-09-28

    ... DEPARTMENT OF HOMELAND SECURITY Coast Guard 33 CFR Part 165 [Docket No. USCG-2012-0767] RIN 1625-AA00 Safety Zone, Changes to Original Rule; Boston Harbor's Rock Removal Project, Boston Inner Harbor... original provisions of that temporary final rule, but adds two additional safety zones necessary for the...

  6. Human vocal tract resonances and the corresponding mode shapes investigated by three-dimensional finite-element modelling based on CT measurement.

    Science.gov (United States)

    Vampola, Tomáš; Horáček, Jaromír; Laukkanen, Anne-Maria; Švec, Jan G

    2015-04-01

    Resonance frequencies of the vocal tract have traditionally been modelled using one-dimensional models. These cannot accurately represent the events in the frequency region of the formant cluster around 2.5-4.5 kHz, however. Here, the vocal tract resonance frequencies and their mode shapes are studied using a three-dimensional finite element model obtained from computed tomography measurements of a subject phonating on vowel [a:]. Instead of the traditional five, up to eight resonance frequencies of the vocal tract were found below the prominent antiresonance around 4.7 kHz. The three extra resonances were found to correspond to modes which were axially asymmetric and involved the piriform sinuses, valleculae, and transverse vibrations in the oral cavity. The results therefore suggest that the phenomenon of speaker's and singer's formant clustering may be more complex than originally thought.

  7. Hydraulic experiment on flow and topography change in harbor due to tsunami and its numerical simulation

    International Nuclear Information System (INIS)

    Fujii, Naoki; Ikeno, Masaaki; Sakakiyama, Tsutomu; Matsuyama, Masafumi; Takao, Makoto; Mukohara, Takeshi

    2009-01-01

    Numerical model of topography change is important to examine collapse of the harbor facilities by sand transport due to tsunami. Problems for evaluation of sand transport due to tsunami with topography change model are in precision of the numerical model and topography change data. Therefore, we installed the harbor in large-scaled wave tank and carried out experiment about tsunami flow and topography change to get those detailed data. For results provided by experimental test, we applied the topography change model of Ikeno et al. (2009a) and evaluated it about the reproduction characteristics. As a result, it was confirmed that reproduction of an experiment improved by using new pickup rate formula proposed by Ikeno et al. (2009a). (author)

  8. Atlas of neutron resonances

    CERN Document Server

    Mughabghab, Said

    2018-01-01

    Atlas of Neutron Resonances: Resonance Properties and Thermal Cross Sections Z= 1-60, Sixth Edition, contains an extensive list of detailed individual neutron resonance parameters for Z=1-60, as well as thermal cross sections, capture resonance integrals, average resonance parameters and a short survey of the physics of thermal and resonance neutrons. The long introduction contains: nuclear physics formulas aimed at neutron physicists; topics of special interest such as valence neutron capture, nuclear level density parameters, and s-, p-, and d-wave neutron strength functions; and various comparisons of measured quantities with the predictions of nuclear models, such as the optical model. As in the last edition, additional features have been added to appeal to a wider spectrum of users. These include: spin-dependent scattering lengths that are of interest to solid-state physicists, nuclear physicists and neutron evaluators; calculated and measured Maxwellian average 5-keV and 30-keV capture cross sections o...

  9. Efficient solution methodology for calibrating the hemodynamic model using functional Magnetic Resonance Imaging (fMRI) measurements

    KAUST Repository

    Zambri, Brian

    2015-11-05

    Our aim is to propose a numerical strategy for retrieving accurately and efficiently the biophysiological parameters as well as the external stimulus characteristics corresponding to the hemodynamic mathematical model that describes changes in blood flow and blood oxygenation during brain activation. The proposed method employs the TNM-CKF method developed in [1], but in a prediction/correction framework. We present numerical results using both real and synthetic functional Magnetic Resonance Imaging (fMRI) measurements to highlight the performance characteristics of this computational methodology. © 2015 IEEE.

  10. Carbon 13 nuclear magnetic resonance chemical shifts empiric calculations of polymers by multi linear regression and molecular modeling

    International Nuclear Information System (INIS)

    Da Silva Pinto, P.S.; Eustache, R.P.; Audenaert, M.; Bernassau, J.M.

    1996-01-01

    This work deals with carbon 13 nuclear magnetic resonance chemical shifts empiric calculations by multi linear regression and molecular modeling. The multi linear regression is indeed one way to obtain an equation able to describe the behaviour of the chemical shift for some molecules which are in the data base (rigid molecules with carbons). The methodology consists of structures describer parameters definition which can be bound to carbon 13 chemical shift known for these molecules. Then, the linear regression is used to determine the equation significant parameters. This one can be extrapolated to molecules which presents some resemblances with those of the data base. (O.L.). 20 refs., 4 figs., 1 tab

  11. Analytical approach for modeling and performance analysis of microring resonators as optical filters with multiple output bus waveguides

    Science.gov (United States)

    Lakra, Suchita; Mandal, Sanjoy

    2017-06-01

    A quadruple micro-optical ring resonator (QMORR) with multiple output bus waveguides is mathematically modeled and analyzed by making use of the delay-line signal processing approach in Z-domain and Mason's gain formula. The performances of QMORR with two output bus waveguides with vertical coupling are analyzed. This proposed structure is capable of providing wider free spectral response from both the output buses with appreciable cross talk. Thus, this configuration could provide increased capacity to insert a large number of communication channels. The simulated frequency response characteristic and its dispersion and group delay characteristics are graphically presented using the MATLAB environment.

  12. Efficient solution methodology for calibrating the hemodynamic model using functional Magnetic Resonance Imaging (fMRI) measurements

    KAUST Repository

    Zambri, Brian; Djellouli, Rabia; Laleg-Kirati, Taous-Meriem

    2015-01-01

    Our aim is to propose a numerical strategy for retrieving accurately and efficiently the biophysiological parameters as well as the external stimulus characteristics corresponding to the hemodynamic mathematical model that describes changes in blood flow and blood oxygenation during brain activation. The proposed method employs the TNM-CKF method developed in [1], but in a prediction/correction framework. We present numerical results using both real and synthetic functional Magnetic Resonance Imaging (fMRI) measurements to highlight the performance characteristics of this computational methodology. © 2015 IEEE.

  13. Wave Climate and Wave Response, 2025 Plan, Kahului Harbor, Maui, Hawaii

    National Research Council Canada - National Science Library

    Thompson, Edward

    2002-01-01

    ... (wind waves and swell) and long waves (harbor oscillations), was used to evaluate the technical feasibility of three alternative modifications to the harbor, including the Kahului Commercial Harbor 2025 Master Plan...

  14. Modeling of mode-locked coupled-resonator optical waveguide lasers

    DEFF Research Database (Denmark)

    Agger, Christian; Skovgård, Troels Suhr; Gregersen, Niels

    2010-01-01

    Coupled-resonator optical waveguides made from coupled high-Q photonic crystal nanocavities are investigated for use as cavities in mode-locked lasers. Such devices show great potential in slowing down light and can serve to reduce the cavity length of a mode-locked laser. An explicit expression...... of the emerging pulse train. A range of tuning around this frequency allows for effective mode locking. Finally, noise is added to the generalized single-cavity eigenfrequencies in order to evaluate the effects of fabrication imperfections on the cold-cavity transmission properties and consequently on the locking...

  15. A particle-hole-rotator coupling model for the giant resonance of carbon-12

    International Nuclear Information System (INIS)

    McDougall, A.; Spicer, B.M.

    1975-01-01

    A collective correlations calculation has been made for the giant resonance of 12 C. The low-lying states are treated as members of two rotational bands, and higher energy low-lying states are included in the coupling procedure in an attempt to examine the connection of these states with structure in the 30-35 MeV region, and to examine a proposed rotational band of states built on the 7.65 MeV (0 + ) level. The calculation fails to transfer strength to the extent expected. (author)

  16. Semi-analytical model of laser resonance absorption in plasmas with a parabolic density profile

    International Nuclear Information System (INIS)

    Pestehe, S J; Mohammadnejad, M

    2010-01-01

    Analytical expressions for mode conversion and resonance absorption of electromagnetic waves in inhomogeneous, unmagnetized plasmas are required for laboratory and simulation studies. Although most of the analyses of this problem have concentrated on the linear plasma density profile, there are a few research works that deal with different plasma density profiles including the parabolic profile. Almost none of them could give clear analytical formulae for the electric and magnetic components of the electromagnetic field propagating through inhomogeneous plasmas. In this paper, we have considered the resonant absorption of laser light near the critical density of plasmas with parabolic electron density profiles followed by a uniform over-dense region and have obtained expressions for the electric and magnetic vectors of laser light propagating through the plasma. An estimation of the fractional absorption of laser energy has also been carried out. It has been shown that, in contrast to the linear density profile, the energy absorption depends explicitly on the value of collision frequency as well as on a new parameter, N, called the over-dense density order.

  17. A Probabilistic and Observation Based Methodology to Estimate Small Craft Harbor Vulnerability to Tsunami Events

    Science.gov (United States)

    Keen, A. S.; Lynett, P. J.; Ayca, A.

    2016-12-01

    Because of the damage resulting from the 2010 Chile and 2011 Japanese tele-tsunamis, the tsunami risk to the small craft marinas in California has become an important concern. The talk will outline an assessment tool which can be used to assess the tsunami hazard to small craft harbors. The methodology is based on the demand and structural capacity of the floating dock system, composed of floating docks/fingers and moored vessels. The structural demand is determined using a Monte Carlo methodology. Monte Carlo methodology is a probabilistic computational tool where the governing might be well known, but the independent variables of the input (demand) as well as the resisting structural components (capacity) may not be completely known. The Monte Carlo approach uses a distribution of each variable, and then uses that random variable within the described parameters, to generate a single computation. The process then repeats hundreds or thousands of times. The numerical model "Method of Splitting Tsunamis" (MOST) has been used to determine the inputs for the small craft harbors within California. Hydrodynamic model results of current speed, direction and surface elevation were incorporated via the drag equations to provide the bases of the demand term. To determine the capacities, an inspection program was developed to identify common features of structural components. A total of six harbors have been inspected ranging from Crescent City in Northern California to Oceanside Harbor in Southern California. Results from the inspection program were used to develop component capacity tables which incorporated the basic specifications of each component (e.g. bolt size and configuration) and a reduction factor (which accounts for the component reduction in capacity with age) to estimate in situ capacities. Like the demand term, these capacities are added probabilistically into the model. To date the model has been applied to Santa Cruz Harbor as well as Noyo River. Once

  18. Stochastic resonance in a piecewise nonlinear model driven by multiplicative non-Gaussian noise and additive white noise

    Science.gov (United States)

    Guo, Yongfeng; Shen, Yajun; Tan, Jianguo

    2016-09-01

    The phenomenon of stochastic resonance (SR) in a piecewise nonlinear model driven by a periodic signal and correlated noises for the cases of a multiplicative non-Gaussian noise and an additive Gaussian white noise is investigated. Applying the path integral approach, the unified colored noise approximation and the two-state model theory, the analytical expression of the signal-to-noise ratio (SNR) is derived. It is found that conventional stochastic resonance exists in this system. From numerical computations we obtain that: (i) As a function of the non-Gaussian noise intensity, the SNR is increased when the non-Gaussian noise deviation parameter q is increased. (ii) As a function of the Gaussian noise intensity, the SNR is decreased when q is increased. This demonstrates that the effect of the non-Gaussian noise on SNR is different from that of the Gaussian noise in this system. Moreover, we further discuss the effect of the correlation time of the non-Gaussian noise, cross-correlation strength, the amplitude and frequency of the periodic signal on SR.

  19. Enhancement of information transmission with stochastic resonance in hippocampal CA1 neuron models: effects of noise input location.

    Science.gov (United States)

    Kawaguchi, Minato; Mino, Hiroyuki; Durand, Dominique M

    2007-01-01

    Stochastic resonance (SR) has been shown to enhance the signal to noise ratio or detection of signals in neurons. It is not yet clear how this effect of SR on the signal to noise ratio affects signal processing in neural networks. In this paper, we investigate the effects of the location of background noise input on information transmission in a hippocampal CA1 neuron model. In the computer simulation, random sub-threshold spike trains (signal) generated by a filtered homogeneous Poisson process were presented repeatedly to the middle point of the main apical branch, while the homogeneous Poisson shot noise (background noise) was applied to a location of the dendrite in the hippocampal CA1 model consisting of the soma with a sodium, a calcium, and five potassium channels. The location of the background noise input was varied along the dendrites to investigate the effects of background noise input location on information transmission. The computer simulation results show that the information rate reached a maximum value for an optimal amplitude of the background noise amplitude. It is also shown that this optimal amplitude of the background noise is independent of the distance between the soma and the noise input location. The results also show that the location of the background noise input does not significantly affect the maximum values of the information rates generated by stochastic resonance.

  20. In vivo tracking of neuronal-like cells by magnetic resonance in rabbit models of spinal cord injury

    Science.gov (United States)

    Zhang, Ruiping; Zhang, Kun; Li, Jianding; Liu, Qiang; Xie, Jun

    2013-01-01

    In vitro experiments have demonstrated that neuronal-like cells derived from bone marrow mesenchymal stem cells can survive, migrate, integrate and help to restore the function and behaviors of spinal cord injury models, and that they may serve as a suitable approach to treating spinal cord injury. However, it is very difficult to track transplanted cells in vivo. In this study, we injected superparamagnetic iron oxide-labeled neuronal-like cells into the subarachnoid space in a rabbit model of spinal cord injury. At 7 days after cell transplantation, a small number of dot-shaped low signal intensity shadows were observed in the spinal cord injury region, and at 14 days, the number of these shadows increased on T2-weighted imaging. Perl's Prussian blue staining detected dot-shaped low signal intensity shadows in the spinal cord injury region, indicative of superparamagnetic iron oxide nanoparticle-labeled cells. These findings suggest that transplanted neuronal-like cells derived from bone marrow mesenchymal stem cells can migrate to the spinal cord injury region and can be tracked by magnetic resonance in vivo. Magnetic resonance imaging represents an efficient noninvasive technique for visually tracking transplanted cells in vivo. PMID:25206659

  1. Current and historic mercury deposition to New Haven Harbor (CT, USA): Implications for industrial coastal environments

    International Nuclear Information System (INIS)

    Clark, Heather F.; Benoit, Gaboury

    2009-01-01

    This study quantifies historic and current mercury contamination in New Haven Harbor (New Haven, Connecticut, USA) through the analysis of sediment cores. The mercury concentration measured in surface sediment ranged from 320 to 1640 μg kg -1 with an average of 530 μg kg -1 . The harbor is relatively small in area (6.6 km 2 ) but displays a large range in concentrations, illustrating the important methodological issue that a large number of samples may be necessary to capture the variability in even a small area. Depth profiles of mercury reflect sedimentation over a range of 20 to 200 years and indicate a complex history of contamination. Mercury depth profiles were compared with lead, copper, cadmium, and silver concentrations and the metals generally covary. This trend indicates that the sources of mercury and heavy metals are linked and that regionally specific sources dominate the historic input of metals rather than large-scale atmospheric deposition patterns. Results also show there are large differences in absolute concentrations of metals among sites in the harbor. Differences in the abundance of Fe-rich, fine-grained sediment likely control the level of metals in various parts of the harbor. Proximity to current sources and the long, diverse industrial history of the harbor also influence the distribution pattern. All of the cores can be modeled as mixing between pre-industrial sediments and either one or two pollution endmembers. This study demonstrates the importance of riverine sources in the mass balance of mercury delivered to coastal areas and of watershed management to preserve coastal ecosystems.

  2. Fundamentals of nanomechanical resonators

    CERN Document Server

    Schmid, Silvan; Roukes, Michael Lee

    2016-01-01

    This authoritative book introduces and summarizes the latest models and skills required to design and optimize nanomechanical resonators, taking a top-down approach that uses macroscopic formulas to model the devices. The authors cover the electrical and mechanical aspects of nano electromechanical system (NEMS) devices. The introduced mechanical models are also key to the understanding and optimization of nanomechanical resonators used e.g. in optomechanics. Five comprehensive chapters address: The eigenmodes derived for the most common continuum mechanical structures used as nanomechanical resonators; The main sources of energy loss in nanomechanical resonators; The responsiveness of micro and nanomechanical resonators to mass, forces, and temperature; The most common underlying physical transduction mechanisms; The measurement basics, including amplitude and frequency noise. The applied approach found in this book is appropriate for engineering students and researchers working with micro and nanomechanical...

  3. Hydrocarbon pollutants shape bacterial community assembly of harbor sediments

    KAUST Repository

    Barbato, Marta; Mapelli, Francesca; Magagnini, Mirko; Chouaia, Bessem; Armeni, Monica; Marasco, Ramona; Crotti, Elena; Daffonchio, Daniele; Borin, Sara

    2016-01-01

    Petroleum pollution results in co-contamination by different classes of molecules, entailing the occurrence of marine sediments difficult to remediate, as in the case of the Ancona harbor (Mediterranean Sea, Italy). Autochthonous bioaugmentation

  4. Extrachromosomal deoxyribonucleic acid in R factor-harboring Enterobacteriaceae

    DEFF Research Database (Denmark)

    Møller, JK; Bak, AL; Christiansen, C

    1976-01-01

    Extrachromosomal deoxyribonucleic acid (DNA) from 24 different R factor-harboring Enterobacteriaceae was isolated and characterized by analytical ultracentrifugation and electron microscopy. The R factors represented 15 different patterns of transferable drug resistance found in enterobacteria from...

  5. 75 FR 76613 - National Pearl Harbor Remembrance Day, 2010

    Science.gov (United States)

    2010-12-09

    .... The deadly attack on Pearl Harbor did not accomplish its mission of breaking the American spirit..., aiding the war effort by working in manufacturing plants, participating in rationing programs, or...

  6. Pearl Harbor, Hawaii 1 arc-second DEM

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The 1/3-second Pearl Harbor Hawaii Elevation Grid provides bathymetric data in ASCII raster format of 1/3-second resolution in geographic coordinates. This grid is...

  7. Submarine Biofouling Control- Chlorination DATS Study at Pearl Harbor

    National Research Council Canada - National Science Library

    Wegand, John

    2001-01-01

    The intent of this document is to sumarize the chlorination studies performed at Naval Station, Pearl Harbor in support of biofouling control initiatives for the submarine community, as requested by NAVSEA 92T...

  8. Ground-water status report, Pearl Harbor area, Hawaii, 1978

    Science.gov (United States)

    Soroos, Ronald L.; Ewart, Charles J.

    1979-01-01

    Increasing demand for freshwater in Hawaii has placed heavy stress on many of the State 's basal aquifer systems. The most heavily stressed of these systems is the Pearl Harbor on Oahu. The Pearl Harbor basal aquifer supplies as much as 277 million gallons per day. Since early in this century, spring discharge has been declining while pumpage has been increasing. Total ground-water discharge has remained steady despite short-term fluctuations. Some wells show general increases in chloride concentration while others remain steady. Chloride concentrations throughout the area show no apparent increase since 1970. Basal water head maps of the Pearl Harbor area clearly reflect the natural discharge points, which are the springs located along the shore near the center of Pearl Harbor. Basal-water hydrographs show a general decline of about 0.09 foot per year. This implies depletion of storage at a rate of about 25 million gallons per day. (USGS).

  9. Generalized viscothermoelasticity theory of dual-phase-lagging model for damping analysis in circular micro-plate resonators

    Science.gov (United States)

    Grover, D.; Seth, R. K.

    2018-05-01

    Analysis and numerical results are presented for the thermoelastic dissipation of a homogeneous isotropic, thermally conducting, Kelvin-Voigt type circular micro-plate based on Kirchhoff's Love plate theory utilizing generalized viscothermoelasticity theory of dual-phase-lagging model. The analytical expressions for thermoelastic damping of vibration and frequency shift are obtained for generalized dual-phase-lagging model and coupled viscothermoelastic plates. The scaled thermoelastic damping has been illustrated in case of circular plate and axisymmetric circular plate for fixed aspect ratio for clamped and simply supported boundary conditions. It is observed that the damping of vibrations significantly depend on time delay and mechanical relaxation times in addition to thermo-mechanical coupling in circular plate under resonance conditions and plate dimensions.

  10. Estimation of the measurement uncertainty in magnetic resonance velocimetry based on statistical models

    Energy Technology Data Exchange (ETDEWEB)

    Bruschewski, Martin; Schiffer, Heinz-Peter [Technische Universitaet Darmstadt, Institute of Gas Turbines and Aerospace Propulsion, Darmstadt (Germany); Freudenhammer, Daniel [Technische Universitaet Darmstadt, Institute of Fluid Mechanics and Aerodynamics, Center of Smart Interfaces, Darmstadt (Germany); Buchenberg, Waltraud B. [University Medical Center Freiburg, Medical Physics, Department of Radiology, Freiburg (Germany); Grundmann, Sven [University of Rostock, Institute of Fluid Mechanics, Rostock (Germany)

    2016-05-15

    Velocity measurements with magnetic resonance velocimetry offer outstanding possibilities for experimental fluid mechanics. The purpose of this study was to provide practical guidelines for the estimation of the measurement uncertainty in such experiments. Based on various test cases, it is shown that the uncertainty estimate can vary substantially depending on how the uncertainty is obtained. The conventional approach to estimate the uncertainty from the noise in the artifact-free background can lead to wrong results. A deviation of up to -75% is observed with the presented experiments. In addition, a similarly high deviation is demonstrated with the data from other studies. As a more accurate approach, the uncertainty is estimated directly from the image region with the flow sample. Two possible estimation methods are presented. (orig.)

  11. Estimation of the measurement uncertainty in magnetic resonance velocimetry based on statistical models

    Science.gov (United States)

    Bruschewski, Martin; Freudenhammer, Daniel; Buchenberg, Waltraud B.; Schiffer, Heinz-Peter; Grundmann, Sven

    2016-05-01

    Velocity measurements with magnetic resonance velocimetry offer outstanding possibilities for experimental fluid mechanics. The purpose of this study was to provide practical guidelines for the estimation of the measurement uncertainty in such experiments. Based on various test cases, it is shown that the uncertainty estimate can vary substantially depending on how the uncertainty is obtained. The conventional approach to estimate the uncertainty from the noise in the artifact-free background can lead to wrong results. A deviation of up to -75 % is observed with the presented experiments. In addition, a similarly high deviation is demonstrated with the data from other studies. As a more accurate approach, the uncertainty is estimated directly from the image region with the flow sample. Two possible estimation methods are presented.

  12. Semi-analytical model for hollow-core anti-resonant fibers

    Directory of Open Access Journals (Sweden)

    Wei eDing

    2015-03-01

    Full Text Available We detailedly describe a recently-developed semi-analytical method to quantitatively calculate light transmission properties of hollow-core anti-resonant fibers (HC-ARFs. Formation of equiphase interface at fiber’s outermost boundary and outward light emission ruled by Helmholtz equation in fiber’s transverse plane constitute the basis of this method. Our semi-analytical calculation results agree well with those of precise simulations and clarify the light leakage dependences on azimuthal angle, geometrical shape and polarization. Using this method, we show investigations on HC-ARFs having various core shapes (e.g. polygon, hypocycloid with single- and multi-layered core-surrounds. The polarization properties of ARFs are also studied. Our semi-analytical method provides clear physical insights into the light guidance in ARF and can play as a fast and useful design aid for better ARFs.

  13. Harbor seal vibrissa morphology suppresses vortex-induced vibrations

    OpenAIRE

    Hanke, Wolf; Witte, Mathias; Miersch, Lars; Brede, Martin; Oeffner, Johannes; Michael, Mark; Hanke, Frederike; Leder, Alfred; Dehnhardt, Guido

    2010-01-01

    Harbor seals (Phoca vitulina) often live in dark and turbid waters, where their mystacial vibrissae, or whiskers, play an important role in orientation. Besides detecting and discriminating objects by direct touch, harbor seals use their whiskers to analyze water movements, for example those generated by prey fish or by conspecifics. Even the weak water movements left behind by objects that have passed by earlier can be sensed and followed accurately (hydrodynamic trail following). While scan...

  14. Satellite Monitoring of Boston Harbor Water Quality: Initial Investigations

    Science.gov (United States)

    Sheldon, P.; Chen, R. F.; Schaaf, C.; Pahlevan, N.; Lee, Z.

    2016-02-01

    The transformation of Boston Harbor from the "dirtiest in America" to a National Park Area is one of the most remarkable estuarine recoveries in the world. A long-term water quality dataset from 1991 to present exists in Boston Harbor due to a $3. 8 billion lawsuit requiring the harbor clean-up. This project uses discrete water sampling and underway transects with a towed vehicle coordinated with Landsat 7 and Landsat 8 to create surface maps of chlorophyll a (Chl a), dissolved organic matter (CDOM and DOC), total suspended solids (TSS), diffuse attenuation coefficient (Kd_490), and photic depth in Boston Harbor. In addition, 3 buoys have been designed, constructed, and deployed in Boston Harbor that measure Chl a and CDOM fluorescence, optical backscatter, salinity, temperature, and meteorological parameters. We are initially using summer and fall of 2015 to develop atmospheric corrections for conditions in Boston Harbor and develop algorithms for Landsat 8 data to estimate in water photic depth, TSS, Chl a, Kd_490, and CDOM. We will report on initial buoy and cruise data and show 2015 Landsat-derived distributions of water quality parameters. It is our hope that once algorithms for present Landsat imagery can be developed, historical maps of water quality can be constructed using in water data back to 1991.

  15. Multiphoton resonances

    International Nuclear Information System (INIS)

    Shore, B.W.

    1977-01-01

    The long-time average of level populations in a coherently-excited anharmonic sequence of energy levels (e.g., an anharmonic oscillator) exhibits sharp resonances as a function of laser frequency. For simple linearly-increasing anharmonicity, each resonance is a superposition of various multiphoton resonances (e.g., a superposition of 3, 5, 7, . . . photon resonances), each having its own characteristic width predictable from perturbation theory

  16. The benefit of non contrast-enhanced magnetic resonance angiography for predicting vascular access surgery outcome: a computer model perspective.

    Directory of Open Access Journals (Sweden)

    Maarten A G Merkx

    Full Text Available INTRODUCTION: Vascular access (VA surgery, a prerequisite for hemodialysis treatment of end-stage renal-disease (ESRD patients, is hampered by complication rates, which are frequently related to flow enhancement. To assist in VA surgery planning, a patient-specific computer model for postoperative flow enhancement was developed. The purpose of this study is to assess the benefit of non contrast-enhanced magnetic resonance angiography (NCE-MRA data as patient-specific geometrical input for the model-based prediction of surgery outcome. METHODS: 25 ESRD patients were included in this study. All patients received a NCE-MRA examination of the upper extremity blood vessels in addition to routine ultrasound (US. Local arterial radii were assessed from NCE-MRA and converted to model input using a linear fit per artery. Venous radii were determined with US. The effect of radius measurement uncertainty on model predictions was accounted for by performing Monte-Carlo simulations. The resulting flow prediction interval of the computer model was compared with the postoperative flow obtained from US. Patients with no overlap between model-based prediction and postoperative measurement were further analyzed to determine whether an increase in geometrical detail improved computer model prediction. RESULTS: Overlap between postoperative flows and model-based predictions was obtained for 71% of patients. Detailed inspection of non-overlapping cases revealed that the geometrical details that could be assessed from NCE-MRA explained most of the differences, and moreover, upon addition of these details in the computer model the flow predictions improved. CONCLUSIONS: The results demonstrate clearly that NCE-MRA does provide valuable geometrical information for VA surgery planning. Therefore, it is recommended to use this modality, at least for patients at risk for local or global narrowing of the blood vessels as well as for patients for whom an US-based model

  17. Robust Sub-harmonic Mixer at 340 GHz Using Intrinsic Resonances of Hammer-Head Filter and Improved Diode Model

    Science.gov (United States)

    Wang, Cheng; He, Yue; Lu, Bin; Jiang, Jun; Miao, Li; Deng, Xian-Jin; Xiong, Yong-zhong; Zhang, Jian

    2017-11-01

    This paper presents a sub-harmonic mixer at 340 GHz based on anti-parallel Schottky diodes (SBDs). Intrinsic resonances in low-pass hammer-head filter have been adopted to enhance the isolation for different harmonic components, while greatly minimizing the transmission loss. The application of new DC grounding structure, impedance matching structure, and suspended micro-strip mitigates the negative influences of fabrication errors from metal cavity, quartz substrate, and micro-assembly. An improved lumped element equivalent circuit model of SBDs guarantees the accuracy of simulation, which takes current-voltage (I/V) behavior, capacitance-voltage (C/V) behavior, carrier velocity saturation, DC series resistor, plasma resonance, skin effect, and four kinds of noise generation mechanisms into consideration thoroughly. The measurement indicates that with local oscillating signal of 2 mW, the lowest double sideband conversion loss is 5.5 dB at 339 GHz; the corresponding DSB noise temperature is 757 K. The 3 dB bandwidth of conversion loss is 50 GHz from 317 to 367 GHz.

  18. Study of the interplay between magnetic shear and resonances using Hamiltonian models for the magnetic field lines

    Science.gov (United States)

    Firpo, M.-C.; Constantinescu, D.

    2011-03-01

    The issue of magnetic confinement in magnetic fusion devices is addressed within a purely magnetic approach. Using some Hamiltonian models for the magnetic field lines, the dual impact of low magnetic shear is shown in a unified way. Away from resonances, it induces a drastic enhancement of magnetic confinement that favors robust internal transport barriers (ITBs) and stochastic transport reduction. When low shear occurs for values of the winding of the magnetic field lines close to low-order rationals, the amplitude thresholds of the resonant modes that break internal transport barriers by allowing a radial stochastic transport of the magnetic field lines may be quite low. The approach can be applied to assess the robustness versus magnetic perturbations of general (almost) integrable magnetic steady states, including nonaxisymmetric ones such as the important single-helicity steady states. This analysis puts a constraint on the tolerable mode amplitudes compatible with ITBs and may be proposed as a possible explanation of diverse experimental and numerical signatures of their collapses.

  19. Modeling and Analysis of Resonance in LCL-Type Grid-Connected Inverters under Different Control Schemes

    Directory of Open Access Journals (Sweden)

    Yanxue Yu

    2017-01-01

    Full Text Available As a basic building block in power systems, the three-phase voltage-source inverter (VSI connects the distributed energy to the grid. For the inductor-capacitor-inductor (LCL-filter three-phase VSI, according to different current sampling position and different reference frame, there mainly exist four control schemes. Different control schemes present different impedance characteristics in their corresponding determined frequency range. To analyze the existing resonance phenomena due to the variation of grid impedances, the sequence impedance models of LCL-type grid-connected three-phase inverters under different control schemes are presented using the harmonic linearization method. The impedance-based stability analysis approach is then applied to compare the relative stability issues due to the impedance differences at some frequencies and to choose the best control scheme and the better controller parameters regulating method for the LCL-type three-phase VSI. The simulation and experiments both validate the resonance analysis results.

  20. Generalized coupling resonance modeling, analysis, and active damping of multi-parallel inverters in microgrid operating in grid-connected mode

    DEFF Research Database (Denmark)

    Chen, Zhiyong; Chen, Yandong; Guerrero, Josep M.

    2016-01-01

    This paper firstly presents an equivalent coupling circuit modeling of multi-parallel inverters in microgrid operating in grid-connected mode. By using the model, the coupling resonance phenomena are explicitly investigated through the mathematical approach, and the intrinsic and extrinsic...

  1. Identifying the default mode network structure using dynamic causal modeling on resting-state functional magnetic resonance imaging.

    Science.gov (United States)

    Di, Xin; Biswal, Bharat B

    2014-02-01

    The default mode network is part of the brain structure that shows higher neural activity and energy consumption when one is at rest. The key regions in the default mode network are highly interconnected as conveyed by both the white matter fiber tracing and the synchrony of resting-state functional magnetic resonance imaging signals. However, the causal information flow within the default mode network is still poorly understood. The current study used the dynamic causal modeling on a resting-state fMRI data set to identify the network structure underlying the default mode network. The endogenous brain fluctuations were explicitly modeled by Fourier series at the low frequency band of 0.01-0.08Hz, and those Fourier series were set as driving inputs of the DCM models. Model comparison procedures favored a model wherein the MPFC sends information to the PCC and the bilateral inferior parietal lobule sends information to both the PCC and MPFC. Further analyses provide evidence that the endogenous connectivity might be higher in the right hemisphere than in the left hemisphere. These data provided insight into the functions of each node in the DMN, and also validate the usage of DCM on resting-state fMRI data. © 2013.

  2. Recent advances in biosynthetic modeling of nitric oxide reductases and insights gained from nuclear resonance vibrational and other spectroscopic studies

    Energy Technology Data Exchange (ETDEWEB)

    Chakraborty, Saumen; Reed, Julian; Sage, Timothy; Branagan, Nicole C.; Petrik, Igor D.; Miner, Kyle D.; Hu, Michael Y.; Zhao, Jiyong; Alp, E. Ercan; Lu, Yi

    2015-10-05

    This Forum Article focuses on recent advances in structural and spectroscopic studies of biosynthetic models of nitric oxide reductases (NORs). NORs are complex metalloenzymes found in the denitrification pathway of Earth's nitrogen cycle where they catalyze the proton-dependent twoelectron reduction of nitric oxide (NO) to nitrous oxide (N2O). While much progress has been made in biochemical and biophysical studies of native NORs and their variants, a. clear mechanistic understanding of this important metalloenzyme related to its function is still elusive. We report herein UV vis and nuclear resonance vibrational spectroscopy (NRVS) studies of mononitrosylated intermediates of the NOR reaction of a biosynthetic model. The ability to selectively substitute metals at either heme or nonheme metal sites allows the introduction of independent 57Fe probe atoms at either site, as well as allowing the preparation of analogues of stable reaction intermediates by replacing either metal with a redox inactive metal. Together with previous structural and spectroscopic results, we summarize insights gained from studying these biosynthetic models toward understanding structural features responsible for the NOR activity and its mechanism. As a result, the outlook on NOR modeling is also discussed, with an emphasis on the design of models capable of catalytic turnovers designed based on close mimics of the secondary coordination sphere of native NORs.

  3. Correlative study of proton magnetic resonance spectroscopy and histopathology in a neonatal piglet model of hypoxic-ischemic encephalopathy

    International Nuclear Information System (INIS)

    Wang Xiaoming; Guo Qiyong; Lin Nan; Ding Changwei; Wang Shuxuan; Chen Liying; Lv Qingjie; Jiang Weiguo

    2005-01-01

    Objective: To evaluate proton magnetic resonance spectroscopy ( 1 H-MRS) in the diagnosis of hypoxic ischemic brain damage (HIBD) in hyperacute period using an animal model. Methods: Twenty-five term piglets at the age of 3 to 7 days were subjected and divided into one control group (n=5) and two experimental groups. 1 H spectrum curve was measured continuously in all cases at 0-6, 20-24, 44-48, and 68-72 h after hypoxic ischemia in frontoparietal region, basal ganglia, and hippocampus. Lac/Cr was calculated. Histopathologic examination included hematoxylin and glial fibrillary acidic protein (GFAP) stain, teminal transferase mediated dUTP-biotin nick- end eosin (HE) stain, labeling (TUNEL) stain, and transmission electron microscope. Results: Lac/Cr in hippocampus region was 0.95 ± 0.88 in control group compared with 5.65 ± 1.93 in model group 1 and 8.93 ± 6.95 in model group 2. Model group 1 showed significantly glial cells swelling in hippocampus region on histopathologic examination. Model group 2 showed neurons and glial cells swelling significantly in hippocampus, and prominent apoptosis was seen in the peripheral neurons and glial cells. Further more Lac/Cr remained high within 72 h. Lac /Cr was 0.41 ± 0.03 in basal ganglia in control group compared with no significant elevation in model group 1 and 13.59 ± 10.23 in model group 2. Model group 1 did not show significant neuron and glial cell pathological changes in basal ganglia. Model group 2 showed obvious glial cell swelling, while neurons changed mildly. Lac/Cr was high within 48 h, and then declined. Lac/Cr in frontoparietal region also increased, but the value was lower than the former two regions. Conclusion: Neurons have an acute energy consumption after hypoxic ischemia, and Lac/Cr reflectes the extent of lesions correctly. (authors)

  4. Experimental flow and perfusion measurement in an animal model with magnetic resonance tomography

    International Nuclear Information System (INIS)

    Schoenberg, S.O.; Bock, M.; Just, A.

    2001-01-01

    Aim. Validation of non-invasive methods for morphologic and functional imaging of the kidney under physiologic and pathophysiologic conditions. Material and Methods. In chronically instrumented animals (foxhounds) comparative measurements of renal flow and perfusion were performed. Magnetic resonance imaging techniques were compared to data obtained from implanted flow probes and total kidney weight post mortem. In the MR system, different degrees of renal artery stenosis could be induced by means of an implanted inflatable cuff. The degree of stenosis was verified with high-resolution 3D contrast-enhanced MR angiography (3D-CE-MRA) using an intravascular contrast agent. Results. The MR-data agreed well with the invasively obtained results. Artifacts resulting from the implanted flow probes and other devices could be kept to a minimum due to appropriate selection of the probe materials and measurement strategies. Stenoses could be reproduced reliably and quantified from the induced morphologic and functional changes. Conclusion. Morphologic and functional MR techniques are well suited for non-invasive in vivo assessment of renal blood flow physiology. (orig.) [de

  5. Characterization of glioblastoma in an orthotopic mouse model with magnetic resonance elastography.

    Science.gov (United States)

    Schregel, Katharina; Nazari, Navid; Nowicki, Michal O; Palotai, Miklos; Lawler, Sean E; Sinkus, Ralph; Barbone, Paul E; Patz, Samuel

    2017-11-29

    Glioblastoma (GBM) is the most common primary brain tumor. It is highly malignant and has a correspondingly poor prognosis. Diagnosis and monitoring are mainly accomplished with MRI, but remain challenging in some cases. Therefore, complementary methods for tumor detection and characterization would be beneficial. Using magnetic resonance elastography (MRE), we performed a longitudinal study of the biomechanical properties of intracranially implanted GBM in mice and compared the results to histopathology. The biomechanical parameters of viscoelastic modulus, shear wave speed and phase angle were significantly lower in tumors compared with healthy brain tissue and decreased over time with tumor progression. Moreover, some MRE parameters revealed sub-regions at later tumor stages, which were not easily detectable on anatomical MRI images. Comparison with histopathology showed that softer tumor regions contained necrosis and patches of viable tumor cells. In contrast, areas of densely packed tumor cells and blood vessels identified with histology coincided with higher values of viscoelastic modulus and shear wave speed. Interestingly, the phase angle was independent from these anatomical variations. In summary, MRE depicted longitudinal and morphological changes in GBM and may prove valuable for tumor characterization in patients. Copyright © 2017 John Wiley & Sons, Ltd.

  6. Synanthropic Cockroaches (Blattidae: Periplaneta spp.) Harbor Pathogenic Leptospira in Colombia.

    Science.gov (United States)

    Gonzalez-Astudillo, Viviana; Bustamante-Rengifo, Javier A; Bonilla, Álvaro; Lehmicke, Anna Joy J; Castillo, Andrés; Astudillo-Hernández, Miryam

    2016-01-01

    Leptospirosis cases in Colombia are typically linked to peridomestic rodents; however, empirical data suggest that Leptospira-infected patients with no apparent exposure to these reservoirs are common. Cockroaches (Periplaneta spp.) have equal or greater interaction with humans than rodents, yet their potential role as carriers of Leptospira has not been assessed. We determined if pathogenic Leptospira is harbored by Periplaneta spp. in Cali (Colombia) and the variables influencing this relationship. Fifty-nine cockroaches were captured from seven sites and DNA was extracted from the body surface and digestive tract for a multiplex polymerase chain reaction, targeting genes secY and flaB. Logistic regression models and proportion tests showed a higher likelihood for Leptospira to be isolated from body surfaces (P > 0.001) and from individuals inside houses (six times more likely). These findings are the first to demonstrate an association between Periplaneta spp. and Leptospira, suggesting the need to investigate the potential for cockroaches to serve as reservoirs or transport hosts for Leptospira. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  7. Tech Talk for Social Studies Teachers Lest We Forget: Remembering Pearl Harbor.

    Science.gov (United States)

    Green, Tim

    2001-01-01

    Presents an annotated bibliography that provides Web sites about Pearl Harbor (Hawaii). Includes Web sites that cover Pearl Harbor history, a live view of Pearl Harbor, stories from people who remember where they were during the attack, information on the naval station at Pearl Harbor, and a virtual tour of the USS Arizona. (CMK)

  8. Fibrillation mechanism of a model intrinsically disordered protein revealed by 2D correlation deep UV resonance Raman spectroscopy.

    Science.gov (United States)

    Sikirzhytski, Vitali; Topilina, Natalya I; Takor, Gaius A; Higashiya, Seiichiro; Welch, John T; Uversky, Vladimir N; Lednev, Igor K

    2012-05-14

    Understanding of numerous biological functions of intrinsically disordered proteins (IDPs) is of significant interest to modern life science research. A large variety of serious debilitating diseases are associated with the malfunction of IDPs including neurodegenerative disorders and systemic amyloidosis. Here we report on the molecular mechanism of amyloid fibrillation of a model IDP (YE8) using 2D correlation deep UV resonance Raman spectroscopy. YE8 is a genetically engineered polypeptide, which is completely unordered at neutral pH yet exhibits all properties of a fibrillogenic protein at low pH. The very first step of the fibrillation process involves structural rearrangements of YE8 at the global structure level without the detectable appearance of secondary structural elements. The formation of β-sheet species follows the global structural changes and proceeds via the simultaneous formation of turns and β-strands. The kinetic mechanism revealed is an important new contribution to understanding of the general fibrillation mechanism proposed for IDP.

  9. Neutral $Z$ boson pair production due to radion resonance in the Randall-Sundrum model: prospects at the CERN LHC

    CERN Document Server

    Das-Prasanta, Kumar

    2005-01-01

    The Neutral $Z$ boson pair production due to radion resonance at the Large Hadron Collider is an interesting process to explore the notion of warped geometry (Randall-Sundrum model). Because of the enhanced coupling of radion with a pair of gluons due to trace enomaly and top(quark)-loop, the radion can provide larger event rate possibility as compared to any New Physics effect. Using the proper radion-top-antitop (with the quarks being off-shell) coupling, we obtain the correct radion production rate at LHC and explore several features of a heavier radion decaying into a pair of real Z bosons which subsequently decays into charged 4 l (l=e, \\mu) leptons (the gold-plated mode). Using the signal and background event rate, we obtain bounds on radion mass $m_\\phi$ and radion vev $\\vphi$ at the $5\\sigma$, $10\\sigma$ discovery level.

  10. Nonperturbative Series Expansion of Green's Functions: The Anatomy of Resonant Inelastic X-Ray Scattering in the Doped Hubbard Model

    Science.gov (United States)

    Lu, Yi; Haverkort, Maurits W.

    2017-12-01

    We present a nonperturbative, divergence-free series expansion of Green's functions using effective operators. The method is especially suited for computing correlators of complex operators as a series of correlation functions of simpler forms. We apply the method to study low-energy excitations in resonant inelastic x-ray scattering (RIXS) in doped one- and two-dimensional single-band Hubbard models. The RIXS operator is expanded into polynomials of spin, density, and current operators weighted by fundamental x-ray spectral functions. These operators couple to different polarization channels resulting in simple selection rules. The incident photon energy dependent coefficients help to pinpoint main RIXS contributions from different degrees of freedom. We show in particular that, with parameters pertaining to cuprate superconductors, local spin excitation dominates the RIXS spectral weight over a wide doping range in the cross-polarization channel.

  11. A study on the complexity of a business cycle model with great excitements in non-resonant condition

    International Nuclear Information System (INIS)

    Ma Junhai; Cui Yaqiang; Liulixia

    2009-01-01

    Based on the researches of Szydlowski and Krawiec, we studied the inherent complexity of a chaotic business cycle with great excitements in non-resonant condition. First, we got the first-order and second-order approximate solutions of the system by using multiple scale method. Then deduced the formulation reflecting the complex relations between vibration, phase, bifurcation parameter μ and excite frequency Ω of first-order solution. As the great excitement F varied, the global changes of the system solutions were analyzed. We also explored the different paths leading the systems with different parameter combinations into catastrophe region, fuzzy region or chaos region. Finally, we discussed the evolution trends of business cycle models under the above-mentioned conditions. Hence, this paper has some theoretical and practical significance.

  12. Advantages of frequency-domain modeling in dynamic-susceptibility contrast magnetic resonance cerebral blood flow quantification.

    Science.gov (United States)

    Chen, Jean J; Smith, Michael R; Frayne, Richard

    2005-03-01

    In dynamic-susceptibility contrast magnetic resonance perfusion imaging, the cerebral blood flow (CBF) is estimated from the tissue residue function obtained through deconvolution of the contrast concentration functions. However, the reliability of CBF estimates obtained by deconvolution is sensitive to various distortions including high-frequency noise amplification. The frequency-domain Fourier transform-based and the time-domain singular-value decomposition-based (SVD) algorithms both have biases introduced into their CBF estimates when noise stability criteria are applied or when contrast recirculation is present. The recovery of the desired signal components from amid these distortions by modeling the residue function in the frequency domain is demonstrated. The basic advantages and applicability of the frequency-domain modeling concept are explored through a simple frequency-domain Lorentzian model (FDLM); with results compared to standard SVD-based approaches. The performance of the FDLM method is model dependent, well representing residue functions in the exponential family while less accurately representing other functions. (c) 2005 Wiley-Liss, Inc.

  13. Determination of aortic compliance from magnetic resonance images using an automatic active contour model

    International Nuclear Information System (INIS)

    Krug, Roland; Boese, Jan M; Schad, Lothar R

    2003-01-01

    The possibility of monitoring changes in aortic elasticity in humans has important applications for clinical trials because it estimates the efficacy of plaque-reducing therapies. The elasticity is usually quantified by compliance measurements. Therefore, the relative temporal change in the vessel cross-sectional area throughout the cardiac cycle has to be determined. In this work we determined and compared the compliance between three magnetic resonance (MR) methods (FLASH, TrueFISP and pulse-wave). Since manual outlining of the aortic wall area is a very time-consuming process and depends on an operator's variability, an algorithm for the automatic segmentation of the artery wall from MR images through the entire heart cycle is presented. The reliable detection of the artery cross-sectional area over the whole heart cycle was possible with a relative error of about 1%. Optimizing the temporal resolution to 60 ms we obtained a relative error in compliance of about 7% from TrueFISP (1.0 x 1.0 x 10 mm 3 , signal-to-noise ratio (SNR) > 12) and FLASH (0.7 x 0.7 x 10 mm 3 , SNR > 12) measurements in volunteers. Pulse-wave measurements yielded an error of more than 9%. In a study of ten volunteers, a compliance between C = 3 x 10 -5 Pa -1 and C = 8 x 10 -5 Pa -1 was determined, depending on age. The results of the TrueFISP and the pulse-wave measurements agreed very well with one another (confidence interval of 1 x 10 -5 Pa -1 ) while the results of the FLASH method more clearly deviated from the TrueFISP and pulse-wave (confidence interval of more than 2 x 10 -5 Pa -1 )

  14. Magnetic Resonance Imaging Identifies Differential Response to Pro-Oxidant Chemotherapy in a Xenograft Model

    Directory of Open Access Journals (Sweden)

    Terry H. Landowski

    2016-06-01

    Full Text Available Induction of oxidative stress is a key component of cancer therapy. Pro-oxidant drugs have been demonstrated to enhance the efficacy of radiotherapy and chemotherapy. An emerging concept is that therapeutic outcomes are dictated by the differential redox buffering reserve in subpopulations of malignant cells, indicating the need for noninvasive biomarkers of tumor redox that can be used for dose identification and response assessment in a longitudinal setting. Magnetic resonance imaging (MRI enhanced with the thiol-binding contrast agent Gd-LC6-SH, and hemodynamic response imaging (HRI in combination with hypercapnia and hyperoxia were investigated as biomarkers of the pharmacodynamics of the small molecule pro-oxidant imexon (IMX. Human multiple myeloma cell lines 8226/S and an IMX-resistant variant, 8226/IM10, were established as contralateral tumors in SCID mice. T1slope, an MRI measure of the washout rate of Gd-LC6-SH, was significantly lower post-IMX therapy in 8226/S tumors compared with vehicle controls, indicating treatment-related oxidization of the tumor microenvironment, which was confirmed by analysis of tumor tissue for thiols. T1slope and ex vivo assays for thiols both indicated a more reduced microenvironment in 8226/IM10 tumors following IMX therapy. HRI with hypercapnia challenge revealed IMX inhibition of vascular dilation in 8226/S tumors but not 8226/IM10 tumors, consistent with decreased immunohistochemical staining for smooth muscle actin in treated 8226/S tumors. MRI enhanced with Gd-LC6-SH, and HRI coupled with a hypercapnic challenge provide noninvasive biomarkers of tumor response to the redox modulator imexon.

  15. A multiparametric magnetic resonance imaging-based risk model to determine the risk of significant prostate cancer prior to biopsy.

    Science.gov (United States)

    van Leeuwen, Pim J; Hayen, Andrew; Thompson, James E; Moses, Daniel; Shnier, Ron; Böhm, Maret; Abuodha, Magdaline; Haynes, Anne-Maree; Ting, Francis; Barentsz, Jelle; Roobol, Monique; Vass, Justin; Rasiah, Krishan; Delprado, Warick; Stricker, Phillip D

    2017-12-01

    To develop and externally validate a predictive model for detection of significant prostate cancer. Development of the model was based on a prospective cohort including 393 men who underwent multiparametric magnetic resonance imaging (mpMRI) before biopsy. External validity of the model was then examined retrospectively in 198 men from a separate institution whom underwent mpMRI followed by biopsy for abnormal prostate-specific antigen (PSA) level or digital rectal examination (DRE). A model was developed with age, PSA level, DRE, prostate volume, previous biopsy, and Prostate Imaging Reporting and Data System (PIRADS) score, as predictors for significant prostate cancer (Gleason 7 with >5% grade 4, ≥20% cores positive or ≥7 mm of cancer in any core). Probability was studied via logistic regression. Discriminatory performance was quantified by concordance statistics and internally validated with bootstrap resampling. In all, 393 men had complete data and 149 (37.9%) had significant prostate cancer. While the variable model had good accuracy in predicting significant prostate cancer, area under the curve (AUC) of 0.80, the advanced model (incorporating mpMRI) had a significantly higher AUC of 0.88 (P prostate cancer. Individualised risk assessment of significant prostate cancer using a predictive model that incorporates mpMRI PIRADS score and clinical data allows a considerable reduction in unnecessary biopsies and reduction of the risk of over-detection of insignificant prostate cancer at the cost of a very small increase in the number of significant cancers missed. © 2017 The Authors BJU International © 2017 BJU International Published by John Wiley & Sons Ltd.

  16. Noninvasive monitoring of radiation-induced treatment response using proton magnetic resonance spectroscopy and diffusion-weighted magnetic resonance imaging in a colorectal tumor model

    International Nuclear Information System (INIS)

    Seierstad, Therese; Roe, Kathrine; Olsen, Dag Rune

    2007-01-01

    Background and purpose: To examine whether in vivo proton magnetic resonance spectroscopy ( 1 H MRS) and diffusion-weighted magnetic resonance imaging (DW-MRI) can monitor radiation-induced changes in HT29 xenografts in mice. Materials and methods: HT29 xenografts in mice received a dose of 15 Gy. In vivo 1 H MRS and DW-MRI were acquired pretreatment and 1, 3, 6 and 10 days post-irradiation. After imaging, tumors were excised for histological analysis. The amounts of necrosis, fibrosis and viable cells in the cross sections were scored and compared to changes in apparent diffusion coefficient (ADC) and choline/water ratio. Results: Radiation-induced necrosis in the xenografts was observed as increased tumor ADC. In-growth of fibrosis three days post-irradiation restricting water mobility was accompanied by decreased tumor ADC. Choline/water ratio correlated with metabolic activity and tumor growth. Conclusions: ADC and choline/water ratio assessed by in vivo DW-MRI and 1 H MRS depicts radiation-induced changes in HT29 xenografts following irradiation

  17. Diffusion tensor magnetic resonance imaging driven growth modeling for radiotherapy target definition in glioblastoma

    DEFF Research Database (Denmark)

    Jensen, Morten B; Guldberg, Trine L; Harbøll, Anja

    2017-01-01

    the microscopic tumor cell spread. Gliomas favor spread along the white matter fiber tracts. Tumor growth models incorporating the MRI diffusion tensors (DTI) allow to account more consistently for the glioma growth. The aim of the study was to investigate the potential of a DTI driven growth model to improve...... target definition in glioblastoma (GBM). MATERIAL AND METHODS: Eleven GBM patients were scanned using T1w, T2w FLAIR, T1w + Gd and DTI. The brain was segmented into white matter, gray matter and cerebrospinal fluid. The Fisher-Kolmogorov growth model was used assuming uniform proliferation...

  18. Non-resonant leptogenesis in seesaw models with an almost conserved B - L

    Energy Technology Data Exchange (ETDEWEB)

    Racker, J., E-mail: racker@ific.uv.es [Universidad de Valencia-CSIC, Depto. de Fisica Teorica and IFIC (Spain)

    2013-03-15

    We review the motivations and some results on leptogenesis in seesaw models with an almost conserved lepton number. The paper is based on a talk given at the 5th International Symposium on Symmetries in Subatomic Physics, SSP2012.

  19. π- -12C elastic scattering above the Δ resonance using diffraction model

    International Nuclear Information System (INIS)

    Arafah, M.R.

    2008-01-01

    Phenomenological analysis of the π - - 12 C elastic scattering differential cross-section at 400, 486, 500, 584, 663, 672 and 766 MeV is presented. The analysis is made in the diffraction model framework using recently proposed parameterization of the phase-shift function. Good description of the experimental data is achieved at all energies. Microscopic interpretation of the parameters of the phase-shift function is provided in terms of Helm's model density parameters. (author)

  20. Understanding the effects of diffusion and relaxation in magnetic resonance imaging using computational modeling

    Science.gov (United States)

    Russell, Greg

    The work described in this dissertation was motivated by a desire to better understand the cellular pathology of ischemic stroke. Two of the three bodies of research presented herein address and issue directly related to the investigation of ischemic stroke through the use of diffusion weighted magnetic resonance imaging (DWMRI) methods. The first topic concerns the development of a computationally efficient finite difference method, designed to evaluate the impact of microscopic tissue properties on the formation of DWMRI signal. For the second body of work, the effect of changing the intrinsic diffusion coefficient of a restricted sample on clinical DWMRI experiments is explored. The final body of work, while motivated by the desire to understand stroke, addresses the issue of acquiring large amounts of MRI data well suited for quantitative analysis in reduced scan time. In theory, the method could be used to generate quantitative parametric maps, including those depicting information gleaned through the use of DWMRI methods. Chapter 1 provides an introduction to several topics. A description of the use of DWMRI methods in the study of ischemic stroke is covered. An introduction to the fundamental physical principles at work in MRI is also provided. In this section the means by which magnetization is created in MRI experiments, how MRI signal is induced, as well as the influence of spin-spin and spin-lattice relaxation are discussed. Attention is also given to describing how MRI measurements can be sensitized to diffusion through the use of qualitative and quantitative descriptions of the process. Finally, the reader is given a brief introduction to the use of numerical methods for solving partial differential equations. In Chapters 2, 3 and 4, three related bodies of research are presented in terms of research papers. In Chapter 2, a novel computational method is described. The method reduces the computation resources required to simulate DWMRI experiments. In

  1. Anomalous solute transport in saturated porous media: Relating transport model parameters to electrical and nuclear magnetic resonance properties

    Science.gov (United States)

    Swanson, Ryan D; Binley, Andrew; Keating, Kristina; France, Samantha; Osterman, Gordon; Day-Lewis, Frederick D.; Singha, Kamini

    2015-01-01

    The advection-dispersion equation (ADE) fails to describe commonly observed non-Fickian solute transport in saturated porous media, necessitating the use of other models such as the dual-domain mass-transfer (DDMT) model. DDMT model parameters are commonly calibrated via curve fitting, providing little insight into the relation between effective parameters and physical properties of the medium. There is a clear need for material characterization techniques that can provide insight into the geometry and connectedness of pore spaces related to transport model parameters. Here, we consider proton nuclear magnetic resonance (NMR), direct-current (DC) resistivity, and complex conductivity (CC) measurements for this purpose, and assess these methods using glass beads as a control and two different samples of the zeolite clinoptilolite, a material that demonstrates non-Fickian transport due to intragranular porosity. We estimate DDMT parameters via calibration of a transport model to column-scale solute tracer tests, and compare NMR, DC resistivity, CC results, which reveal that grain size alone does not control transport properties and measured geophysical parameters; rather, volume and arrangement of the pore space play important roles. NMR cannot provide estimates of more-mobile and less-mobile pore volumes in the absence of tracer tests because these estimates depend critically on the selection of a material-dependent and flow-dependent cutoff time. Increased electrical connectedness from DC resistivity measurements are associated with greater mobile pore space determined from transport model calibration. CC was hypothesized to be related to length scales of mass transfer, but the CC response is unrelated to DDMT.

  2. Experimental models of brain ischemia: a review of techniques, magnetic resonance imaging and investigational cell-based therapies

    Directory of Open Access Journals (Sweden)

    Alessandra eCanazza

    2014-02-01

    Full Text Available Stroke continues to be a significant cause of death and disability worldwide. Although major advances have been made in the past decades in prevention, treatment and rehabilitation, enormous challenges remain in the way of translating new therapeutic approaches from bench to bedside. Thrombolysis, while routinely used for ischemic stroke, is only a viable option within a narrow time window. Recently, progress in stem cell biology has opened up avenues to therapeutic strategies aimed at supporting and replacing neural cells in infarcted areas. Realistic experimental animal models are crucial to understand the mechanisms of neuronal survival following ischemic brain injury and to develop therapeutic interventions. Current studies on experimental stroke therapies evaluate the efficiency of neuroprotective agents and cell-based approaches using primarily rodent models of permanent or transient focal cerebral ischemia. In parallel, advancements in imaging techniques permit better mapping of the spatial-temporal evolution of the lesioned cortex and its functional responses. This review provides a condensed conceptual review of the state of the art of this field, from models and magnetic resonance imaging techniques through to stem cell therapies.

  3. BATMAN--an R package for the automated quantification of metabolites from nuclear magnetic resonance spectra using a Bayesian model.

    Science.gov (United States)

    Hao, Jie; Astle, William; De Iorio, Maria; Ebbels, Timothy M D

    2012-08-01

    Nuclear Magnetic Resonance (NMR) spectra are widely used in metabolomics to obtain metabolite profiles in complex biological mixtures. Common methods used to assign and estimate concentrations of metabolites involve either an expert manual peak fitting or extra pre-processing steps, such as peak alignment and binning. Peak fitting is very time consuming and is subject to human error. Conversely, alignment and binning can introduce artefacts and limit immediate biological interpretation of models. We present the Bayesian automated metabolite analyser for NMR spectra (BATMAN), an R package that deconvolutes peaks from one-dimensional NMR spectra, automatically assigns them to specific metabolites from a target list and obtains concentration estimates. The Bayesian model incorporates information on characteristic peak patterns of metabolites and is able to account for shifts in the position of peaks commonly seen in NMR spectra of biological samples. It applies a Markov chain Monte Carlo algorithm to sample from a joint posterior distribution of the model parameters and obtains concentration estimates with reduced error compared with conventional numerical integration and comparable to manual deconvolution by experienced spectroscopists. http://www1.imperial.ac.uk/medicine/people/t.ebbels/ t.ebbels@imperial.ac.uk.

  4. Glutamate and GABA in autism spectrum disorder-a translational magnetic resonance spectroscopy study in man and rodent models.

    Science.gov (United States)

    Horder, Jamie; Petrinovic, Marija M; Mendez, Maria A; Bruns, Andreas; Takumi, Toru; Spooren, Will; Barker, Gareth J; Künnecke, Basil; Murphy, Declan G

    2018-05-25

    Autism spectrum disorder (ASD) is a pervasive neurodevelopmental syndrome with a high human and economic burden. The pathophysiology of ASD is largely unclear, thus hampering development of pharmacological treatments for the core symptoms of the disorder. Abnormalities in glutamate and GABA signaling have been hypothesized to underlie ASD symptoms, and may form a therapeutic target, but it is not known whether these abnormalities are recapitulated in humans with ASD, as well as in rodent models of the disorder. We used translational proton magnetic resonance spectroscopy ([1H]MRS) to compare glutamate and GABA levels in adult humans with ASD and in a panel of six diverse rodent ASD models, encompassing genetic and environmental etiologies. [1H]MRS was performed in the striatum and the medial prefrontal cortex, of the humans, mice, and rats in order to allow for direct cross-species comparisons in specific cortical and subcortical brain regions implicated in ASD. In humans with ASD, glutamate concentration was reduced in the striatum and this was correlated with the severity of social symptoms. GABA levels were not altered in either brain region. The reduction in striatal glutamate was recapitulated in mice prenatally exposed to valproate, and in mice and rats carrying Nlgn3 mutations, but not in rodent ASD models with other etiologies. Our findings suggest that glutamate/GABA abnormalities in the corticostriatal circuitry may be a key pathological mechanism in ASD; and may be linked to alterations in the neuroligin-neurexin signaling complex.

  5. ON THE MIGRATION OF JUPITER AND SATURN: CONSTRAINTS FROM LINEAR MODELS OF SECULAR RESONANT COUPLING WITH THE TERRESTRIAL PLANETS

    International Nuclear Information System (INIS)

    Agnor, Craig B.; Lin, D. N. C.

    2012-01-01

    We examine how the late divergent migration of Jupiter and Saturn may have perturbed the terrestrial planets. Using a modified secular model we have identified six secular resonances between the ν 5 frequency of Jupiter and Saturn and the four apsidal eigenfrequencies of the terrestrial planets (g 1-4 ). We derive analytic upper limits on the eccentricity and orbital migration timescale of Jupiter and Saturn when these resonances were encountered to avoid perturbing the eccentricities of the terrestrial planets to values larger than the observed ones. Because of the small amplitudes of the j = 2, 3 terrestrial eigenmodes the g 2 – ν 5 and g 3 – ν 5 resonances provide the strongest constraints on giant planet migration. If Jupiter and Saturn migrated with eccentricities comparable to their present-day values, smooth migration with exponential timescales characteristic of planetesimal-driven migration (τ ∼ 5-10 Myr) would have perturbed the eccentricities of the terrestrial planets to values greatly exceeding the observed ones. This excitation may be mitigated if the eccentricity of Jupiter was small during the migration epoch, migration was very rapid (e.g., τ ∼< 0.5 Myr perhaps via planet-planet scattering or instability-driven migration) or the observed small eccentricity amplitudes of the j = 2, 3 terrestrial modes result from low probability cancellation of several large amplitude contributions. Results of orbital integrations show that very short migration timescales (τ < 0.5 Myr), characteristic of instability-driven migration, may also perturb the terrestrial planets' eccentricities by amounts comparable to their observed values. We discuss the implications of these constraints for the relative timing of terrestrial planet formation, giant planet migration, and the origin of the so-called Late Heavy Bombardment of the Moon 3.9 ± 0.1 Ga ago. We suggest that the simplest way to satisfy these dynamical constraints may be for the bulk of any giant

  6. 33 CFR 207.610 - St. Lawrence River, Cape Vincent Harbor, N.Y.; use, administration, and navigation of the harbor...

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false St. Lawrence River, Cape Vincent Harbor, N.Y.; use, administration, and navigation of the harbor and U.S. breakwater. 207.610 Section 207... NAVIGATION REGULATIONS § 207.610 St. Lawrence River, Cape Vincent Harbor, N.Y.; use, administration, and...

  7. Synchrobetatron resonances

    International Nuclear Information System (INIS)

    1977-03-01

    At the 1975 Particle Accelerator Conference it was reported that a class of resonances were observed in SPEAR II that had not appeared before in SPEAR I. While the existence of sideband resonances of the main betatron oscillation frequencies has been previously observed and analyzed, the resonances observed in SPEAR do not appear to be of the same variety. Experiments were performed at SPEAR to identify the mechanism believed to be the most likely explanation. Some of the current experimental knowledge and theoretical views on the source of these resonances are presented

  8. Snake resonances

    International Nuclear Information System (INIS)

    Tepikian, S.

    1988-01-01

    Siberian Snakes provide a practical means of obtaining polarized proton beams in large accelerators. The effect of snakes can be understood by studying the dynamics of spin precession in an accelerator with snakes and a single spin resonance. This leads to a new class of energy independent spin depolarizing resonances, called snake resonances. In designing a large accelerator with snakes to preserve the spin polarization, there is an added constraint on the choice of the vertical betatron tune due to the snake resonances. 11 refs., 4 figs

  9. Littoral cells and harbor dredging along the California coast

    Science.gov (United States)

    Griggs, Gary B.

    1987-02-01

    Beach compartments or littoral cells form the framework for our understanding of the sources, transport, and sinks of sand in the nearshore zone. In general, along the California coast, beach sand is derived from rivers or clifferosion, moves alongshore under the influence of the prevailing waver conditions, and ultimately is lost either to a submarine canyon or a dune field. Marinas or harbors built either between or at the upcoast ends of beach compartments have been relatively maintenance-free, because of a lack of significant littoral drift at these locations. On the other hand, those harbors built in the middle reaches or at the downcoast ends of littoral cells have had expensive annual dredging problems, because of the interruption of large volumes of littoral drift. Although engineers have labored for years on various breakwater, jetty, or entrance channel configurations, the actual design utilized is of secondary importance. The critical factors are harbor location within a littoral cell and annual litoral drift volume.

  10. Respiratory properties of blood in the harbor porpoise, Phocoena phocoena

    DEFF Research Database (Denmark)

    Soegaard, Lisette B; Hansen, Marie N; van Elk, Cornelis

    2012-01-01

    Harbor porpoises are active divers that exchange O(2) and CO(2) with the environment during a fast single breath upon surfacing. We investigated blood O(2)-transporting properties, buffer characteristics, Cl(-) transport via the erythrocyte anion exchanger (AE1), circulating nitric oxide metaboli......Harbor porpoises are active divers that exchange O(2) and CO(2) with the environment during a fast single breath upon surfacing. We investigated blood O(2)-transporting properties, buffer characteristics, Cl(-) transport via the erythrocyte anion exchanger (AE1), circulating nitric oxide....... The true plasma non-bicarbonate buffer value was moderately higher than in terrestrial mammals and increased upon deoxygenation. Plasma bicarbonate was also relatively high, contributing to increase the overall buffer capacity. The apparent Cl(-) permeability of harbor porpoise erythrocytes was similar......, plasma nitrate and hemoglobin-mediated nitrite reduction were elevated compared with mammalian standards, suggesting that increased nitric oxide bioavailability and nitrite-derived nitric oxide could play important roles in diving physiology....

  11. Validation of model-based brain shift correction in neurosurgery via intraoperative magnetic resonance imaging: preliminary results

    Science.gov (United States)

    Luo, Ma; Frisken, Sarah F.; Weis, Jared A.; Clements, Logan W.; Unadkat, Prashin; Thompson, Reid C.; Golby, Alexandra J.; Miga, Michael I.

    2017-03-01

    The quality of brain tumor resection surgery is dependent on the spatial agreement between preoperative image and intraoperative anatomy. However, brain shift compromises the aforementioned alignment. Currently, the clinical standard to monitor brain shift is intraoperative magnetic resonance (iMR). While iMR provides better understanding of brain shift, its cost and encumbrance is a consideration for medical centers. Hence, we are developing a model-based method that can be a complementary technology to address brain shift in standard resections, with resource-intensive cases as referrals for iMR facilities. Our strategy constructs a deformation `atlas' containing potential deformation solutions derived from a biomechanical model that account for variables such as cerebrospinal fluid drainage and mannitol effects. Volumetric deformation is estimated with an inverse approach that determines the optimal combinatory `atlas' solution fit to best match measured surface deformation. Accordingly, preoperative image is updated based on the computed deformation field. This study is the latest development to validate our methodology with iMR. Briefly, preoperative and intraoperative MR images of 2 patients were acquired. Homologous surface points were selected on preoperative and intraoperative scans as measurement of surface deformation and used to drive the inverse problem. To assess the model accuracy, subsurface shift of targets between preoperative and intraoperative states was measured and compared to model prediction. Considering subsurface shift above 3 mm, the proposed strategy provides an average shift correction of 59% across 2 cases. While further improvements in both the model and ability to validate with iMR are desired, the results reported are encouraging.

  12. FISIC - a full-wave code to model ion cyclotron resonance heating of tokamak plasmas

    International Nuclear Information System (INIS)

    Kruecken, T.

    1988-08-01

    We present a user manual for the FISIC code which solves the integrodifferential wave equation in the finite Larmor radius approximation in fully toroidal geometry to simulate ICRF heating experiments. The code models the electromagnetic wave field as well as antenna coupling and power deposition profiles in axisymmetric plasmas. (orig.)

  13. Comments and critique of the Ω anti Ω model for the new resonances

    International Nuclear Information System (INIS)

    Tow, D.M.

    1975-01-01

    The suggestion that the psi particles are Ω anti Ω compounds is briefly reviewed. Various arguments for their small widths are discussed. Crucial tests of the model are pointed out. Also comments are made on psi'' (4.15) and other B anti B systems. (U.S.)

  14. Faunal and vegetation monitoring in response to harbor dredging in the Port of Miami

    Science.gov (United States)

    Daniels, Andre; Stevenson, Rachael; Smith, Erin; Robblee, Michael

    2018-04-11

    Seagrasses are highly productive ecosystems. A before-after-control-impact (BACI) design was used to examine effects of dredging on seagrasses and the animals that inhabit them. The control site North Biscayne Bay and the affected site Port of Miami had seagrass densities decrease during both the before, Fish and Invertebrate Assessment Network 2006-2011, and after, Faunal Monitoring in Response to Harbor Dredging 2014-2016, studies. Turbidity levels increased at North Biscayne Bay and Port of Miami basins during the Faunal Monitoring in Response to Harbor Dredging study, especially in 2016. Animal populations decreased significantly in North Biscayne Bay and Port of Miami in the Faunal Monitoring in Response to Harbor Dredging study compared to the Fish and Invertebrate Assessment Network study. Predictive modeling shows that numbers of animal populations will likely continue to decrease if the negative trends in seagrass densities continue unabated. There could be effects on several fisheries vital to the south Florida economy. Additional research could determine if animal populations and seagrass densities have rebounded or continued to decrease.

  15. The effects of a local moderate tsunami in the Dover Strait on the French and English main harbors of the English Channel

    Science.gov (United States)

    Clément, Cécile; Gailler, Audrey; Heinrich, Philippe; Hélène, Hébert; Loevenbruck, Anne

    2017-04-01

    The Dover Strait is regularly shaken by small to moderate earthquakes which can be felt in the nearby cities Boulogne-Sur-Mer, Calais, Dover and Folkestone. Three destructive events have been documented during the Middle Ages including 1580 Dover Strait earthquake which has been largely felt in London. The isoseimal map of this main event shows a maximum MSK paleointensity of VIII in Calais and VII in Dover [Neilson et al 1984; Melville et al. 1996]. The Dover Strait has been studied using seismic-reflection method [Garcia-Moreno et al. 2014], seafloor sampling, boreholes and gravity anomaly [Everaerts and Mansy 2001], yet the actual tectonic context of the area stays hard to understand because of the lack of recent seafloor deformation and of large recent seismic events. Among other things the occurrence of a tsunamigenic earthquake is not totally impossible [Roger and Gunnell 2011]. We propose several numerical simulations of tsunamis where the seismic scenari are chosen according to the latest fault activity study of the area [Garcia-Moreno et al. 2014]. We used strike-slip and normal mechanisms for magnitudes ranging from 6.0 to 7.0. The propagation of the tsunamis from the source to the French an English coasts is made using a bathymetry with a grid step of 20m realized by the SHOM (Service Hydrographique et Océanographique de la Marine) within the TANDEM project. Using synthetic gauges, we measure the water elevation prediction at the entrance of the main harbours. We push the investigation further for the case of Boulogne-Sur-Mer where the available topography-bathymetry map has a grid step of 10m. This fine bathymetry map enables to modelize the bassins and the embankments inside the harbor and thus to study the resonance of the site. Moreover Boulogne harbor is equipped with a maregraph that we use to compare the synthetic data with real water height registration. Using maregraph recording of rough sea or storm, we are able to evaluate the relevance of

  16. 33 CFR 110.87 - Henderson Harbor, N.Y.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Henderson Harbor, N.Y. 110.87... ANCHORAGE REGULATIONS Special Anchorage Areas § 110.87 Henderson Harbor, N.Y. (a) Area A. The area in the... latitude 43°51′08.8″ N, longitude 76°12′08.9″ W, thence to latitude 43°51′09.0″ N, longitude 76°12′19.0″ W...

  17. Extrachromosomal deoxyribonucleic acid in R factor-harboring Enterobacteriaceae

    DEFF Research Database (Denmark)

    Møller, JK; Bak, AL; Christiansen, C

    1976-01-01

    Extrachromosomal deoxyribonucleic acid (DNA) from 24 different R factor-harboring Enterobacteriaceae was isolated and characterized by analytical ultracentrifugation and electron microscopy. The R factors represented 15 different patterns of transferable drug resistance found in enterobacteria from...... from 1.700 to 1.720 g/cm3. The majority of the bacteria contained extrachromosomal DNAs of various densities. Three-fourths of the R factors were classified as fi+. The investigation illustrates the extensive variability in the physical characteristics of plasmid DNA from R factor-harboring strains....

  18. Properties of spiral resonators

    International Nuclear Information System (INIS)

    Haeuser, J.

    1989-10-01

    The present thesis deals with the calculation and the study of the application possibilities of single and double spiral resonators. The main aim was the development and the construction of reliable and effective high-power spiral resonators for the UNILAC of the GSI in Darmstadt and the H - -injector for the storage ring HERA of DESY in Hamburg. After the presentation of the construction and the properties of spiral resonators and their description by oscillating-circuit models the theoretical foundations of the bunching are presented and some examples of a rebuncher and debuncher and their influence on the longitudinal particle dynamics are shown. After the description of the characteristic accelerator quantities by means of an oscillating-circuit model and the theory of an inhomogeneous λ/4 line it is shown, how the resonance frequency and the efficiency of single and double spiral resonators can be calculated from the geometrical quantities of the structure. In the following the dependence of the maximal reachable resonator voltage in dependence on the gap width and the surface of the drift tubes is studied. Furthermore the high-power resonators are presented, which were built for the different applications for the GSI in Darmstadt, DESY in Hamburg, and for the FOM Institute in Amsterdam. (orig./HSI) [de

  19. A double-layer based model of ion confinement in electron cyclotron resonance ion source

    Energy Technology Data Exchange (ETDEWEB)

    Mascali, D., E-mail: davidmascali@lns.infn.it; Neri, L.; Celona, L.; Castro, G.; Gammino, S.; Ciavola, G. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud, via S. Sofia 62, 95123 Catania (Italy); Torrisi, G. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud, via S. Sofia 62, 95123 Catania (Italy); Università Mediterranea di Reggio Calabria, Dipartimento di Ingegneria dell’Informazione, delle Infrastrutture e dell’Energia Sostenibile, Via Graziella, I-89100 Reggio Calabria (Italy); Sorbello, G. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Sud, via S. Sofia 62, 95123 Catania (Italy); Università degli Studi di Catania, Dipartimento di Ingegneria Elettrica Elettronica ed Informatica, Viale Andrea Doria 6, 95125 Catania (Italy)

    2014-02-15

    The paper proposes a new model of ion confinement in ECRIS, which can be easily generalized to any magnetic configuration characterized by closed magnetic surfaces. Traditionally, ion confinement in B-min configurations is ascribed to a negative potential dip due to superhot electrons, adiabatically confined by the magneto-static field. However, kinetic simulations including RF heating affected by cavity modes structures indicate that high energy electrons populate just a thin slab overlapping the ECR layer, while their density drops down of more than one order of magnitude outside. Ions, instead, diffuse across the electron layer due to their high collisionality. This is the proper physical condition to establish a double-layer (DL) configuration which self-consistently originates a potential barrier; this “barrier” confines the ions inside the plasma core surrounded by the ECR surface. The paper will describe a simplified ion confinement model based on plasma density non-homogeneity and DL formation.

  20. Schizophrenia as a disconnection syndrome. Studies with functional magnetic resonance imaging and structural equation modeling

    International Nuclear Information System (INIS)

    Schloesser, R.; Wagner, G.; Koehler, S.; Sauer, H.

    2005-01-01

    Aside from characteristic psychopathological symptoms, cognitive deficits are a core feature of schizophrenia. These deficits can only be addressed within the context of widespread functional interactions among different brain areas. To examine these interactions, structural equation modeling (SEM) was used for the analysis of fMRI datasets. In a series of studies, both in antipsychotic-treated and drug-free schizophrenic patients, a pattern of enhanced thalamocortical functional connectivity could be observed as an indicator for possible disruptions of frontostriatal thalamocortical circuitry. Moreover, drug-free patients and those receiving typical antipsychotic drugs were characterized by reduced interhemispheric corticocortical connectivity. This difference relative to normal controls was less in patients under atypical antipsychotic drugs. The results could be interpreted as a beneficial effect of atypical antipsychotic drugs on information processing in schizophrenic patients. The present findings are consistent with the model of schizophrenia as a disconnection syndrome and earlier concepts of ''cognitive dysmetria'' in schizophrenia. (orig.) [de

  1. Resonance-sum model for Reggeization in the scattering of particles with arbitrary spin

    International Nuclear Information System (INIS)

    King, M.J.; Durand, L.; Wali, K.C.

    1976-01-01

    Using a field-theoretic description of nonzero-spin particles, center-of-mass helicity amplitudes have been obtained which correspond to pole terms in four-particle reactions with arbitrary-spin external particles. Construction of a van Hove-Durand--type model starting from these helicity amplitudes (which have a well specified kinematic structure in the field-theoretic description) is discussed. Special attention has been paid to boson-fermion scattering. Straightforward Reggeization of helicity amplitudes assuming linear trajectories is known to produce parity doubling. One cannot have a pure fermion Regge pole unaccompanied by cuts. This conclusion has important consequences on both fitting data using Regge formulas in, say, backward scattering in boson-fermion scattering and theoretical considerations such as dual bootstrap models

  2. Evaluating coronary reperfusion during acute myocardial infarction in a canine model by gadolinium-DTPA-enhanced magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Tanabe, Kazuaki; Ishibashi, Yutaka; Shimada, Toshio (Shimane Medical Univ., Izumo (Japan)) (and others)

    1993-05-01

    In previous studies, magnetic resonance imaging (MRI) using contrast agents was found to be useful in distinguishing reperfused infarcts from nonreperfused infarcts. However, there have been only a few detailed studies using consecutive MR images for the assessment of myocardial reperfusion during an acute infarction and also no studies have been performed using a percutaneous transluminal coronary occlusion model (closed chest model). We induced acute myocardial infarction in dogs by occluding and then reperfusing the coronary artery with a balloon catheter. ECG-gated MR images were taken using the spin-echo technique before and after Gd-DTPA injection during both coronary artery occlusion and after reperfusion. We defined the intensity ratio (IR) as the signal intensity at the ischemic area divided by that at the nonischemic area on MR images and compared each image by the IR. Without Gd-DTPA, there was no difference between infarcted and normally perfused myocardium. Infarcted myocardium had a low signal intensity (IR=0.68[+-]0.14) soon after Gd-DTPA injection. This difference diminished with time. After reperfusion the infarcted myocardium had a high signal intensity (IR: 1.76[+-]0.34). We conclude that Gd-DTPA-enhanced MRI can distinguish reperfused from nonreperfused infarcts soon after Gd-DTPA administration. (author).

  3. Effects of Liver Fibrosis Progression on Tissue Relaxation Times in Different Mouse Models Assessed by Ultrahigh Field Magnetic Resonance Imaging

    Directory of Open Access Journals (Sweden)

    Andreas Müller

    2017-01-01

    Full Text Available Recently, clinical studies demonstrated that magnetic resonance relaxometry with determination of relaxation times T1 and T2⁎ may aid in staging and management of liver fibrosis in patients suffering from viral hepatitis and steatohepatitis. In the present study we investigated T1 and T2⁎ in different models of liver fibrosis to compare alternate pathophysiologies in their effects on relaxation times and to further develop noninvasive quantification methods of liver fibrosis. MRI was performed with a fast spin echo sequence for measurement of T1 and a multigradient echo sequence for determination of T2⁎. Toxic liver fibrosis was induced by injections of carbon tetrachloride (1.4 mL CCl4 per kg bodyweight and week, for 3 or 6 weeks in BALB/cJ mice. Chronic sclerosing cholangitis was mimicked using the ATP-binding cassette transporter B4 knockout (Abcb4 -/- mouse model. Untreated BALB/cJ mice served as controls. To assess hepatic fibrosis, we ascertained collagen contents and fibrosis scores after Sirius red staining. T1 and T2⁎ correlate differently to disease severity and etiology of liver fibrosis. T2⁎ shows significant decrease correlating with fibrosis in CCl4 treated animals, while demonstrating significant increase with disease severity in Abcb4 -/- mice. Measurements of T1 and T2⁎ may therefore facilitate discrimination between different stages and causes of liver fibrosis.

  4. Evaluating coronary reperfusion during acute myocardial infarction in a canine model by gadolinium-DTPA-enhanced magnetic resonance imaging

    International Nuclear Information System (INIS)

    Tanabe, Kazuaki; Ishibashi, Yutaka; Shimada, Toshio

    1993-01-01

    In previous studies, magnetic resonance imaging (MRI) using contrast agents was found to be useful in distinguishing reperfused infarcts from nonreperfused infarcts. However, there have been only a few detailed studies using consecutive MR images for the assessment of myocardial reperfusion during an acute infarction and also no studies have been performed using a percutaneous transluminal coronary occlusion model (closed chest model). We induced acute myocardial infarction in dogs by occluding and then reperfusing the coronary artery with a balloon catheter. ECG-gated MR images were taken using the spin-echo technique before and after Gd-DTPA injection during both coronary artery occlusion and after reperfusion. We defined the intensity ratio (IR) as the signal intensity at the ischemic area divided by that at the nonischemic area on MR images and compared each image by the IR. Without Gd-DTPA, there was no difference between infarcted and normally perfused myocardium. Infarcted myocardium had a low signal intensity (IR=0.68±0.14) soon after Gd-DTPA injection. This difference diminished with time. After reperfusion the infarcted myocardium had a high signal intensity (IR: 1.76±0.34). We conclude that Gd-DTPA-enhanced MRI can distinguish reperfused from nonreperfused infarcts soon after Gd-DTPA administration. (author)

  5. The gastro-esophageal reflux barrier: biophysical analysis on 3D models of anatomy from magnetic resonance imaging.

    Science.gov (United States)

    Roy, S; Fox, M R; Curcic, J; Schwizer, W; Pal, A

    2012-07-01

    The function and structure of the gastro-esophageal junction (GEJ) determine its efficacy as a reflux barrier. This study presents a novel methodology for the quantitative assessment of GEJ and proximal gastric morphology from magnetic resonance (MR) imaging. Based on this data we propose a new conceptualization of the hypothesis that a flap valve mechanism contributes to reflux protection. 3D models of the GEJ and proximal stomach were reconstructed from MR images in 12 healthy volunteers during respiration and on eating a test meal to maximum satiation. A rotating plane analysis measured the gastro-esophageal insertion angle and span of contact. An ellipsoid fit provided quantitative assessment of gastric shape and orientation relative to a fixed anatomical reference point. Position of the esophageal insertion on the 'gastric ellipse' was noted. An ellipsoid-cylinder model was designed to analyze the relationships among parameters describing the GEJ morphology. The insertion angle became more acute on expiration, but did not change with meal ingestion. In contrast the span of contact did not vary with respiration, but increased with gastric filling. Changes in gastric morphology with distension further augmented the span of gastro-esophageal contact in almost 70% of the studies. Novel MR imaging and biophysical analysis of the GEJ and proximal stomach provide a quantitative description of structures contributing to the reflux barrier. Changes in these parameters during respiration and on eating support the hypothesis that structural components of a functional 'flap valve' like mechanism contribute to reflux protection. © 2012 Blackwell Publishing Ltd.

  6. On the electromechanical modelling of a resonating nano-cantilever-based transducer

    DEFF Research Database (Denmark)

    Teva, J.; Abadal, G.; Davis, Zachary James

    2004-01-01

    deflection and the frequency response of the oscillation amplitude for different voltage polarization conditions. For the electrostatic force calculation the model takes into account the real deflection shape of the cantilever and the contribution to the cantilever-driver capacitance of the fringing field....... Both the static and dynamic predictions have been validated experimentally by measuring the deflection of the cantilever by means of an optical microscope. (C) 2004 Elsevier B.V. All rights reserved....

  7. Measurements and modelling of fast-ion redistribution due to resonant MHD instabilities in MAST

    International Nuclear Information System (INIS)

    Jones, O M; Cecconello, M; Klimek, I; McClements, K G; Akers, R J; Keeling, D L; Meakins, A J; Sharapov, S E; Boeglin, W U; Perez, R V; Turnyanskiy, M

    2015-01-01

    The results of a comprehensive investigation into the effects of toroidicity-induced Alfvén eigenmodes (TAE) and energetic particle modes on the NBI-generated fast-ion population in MAST plasmas are reported. Fast-ion redistribution due to frequency-chirping TAE in the range 50 kHz–100 kHz and frequency-chirping energetic particle modes known as fishbones in the range 20 kHz–50 kHz, is observed. TAE and fishbones are also observed to cause losses of fast ions from the plasma. The spatial and temporal evolution of the fast-ion distribution is determined using a fission chamber, a radially-scanning collimated neutron flux monitor, a fast-ion deuterium alpha spectrometer and a charged fusion product detector. Modelling using the global transport analysis code Transp, with ad hoc anomalous diffusion and fishbone loss models introduced, reproduces the coarsest features of the affected fast-ion distribution in the presence of energetic particle-driven modes. The spectrally and spatially resolved measurements show, however, that these models do not fully capture the effects of chirping modes on the fast-ion distribution. (paper)

  8. Multiquark resonant states

    International Nuclear Information System (INIS)

    Shahbazian, B.A.

    1982-01-01

    The invariant mass spectra of forty nine hadronic systems with hypercharge, strangeness and baryon number, varied in wide limits have been studied. Resonance peaks have been found in the invariant mass spectra of Y 2 and #betta#pπ 2495 MeV/c 2 resonant states. Three more candidates for anti qq 4 states were found #bettaπ# + π + : 1705, 2072, 2605 MeV/c 2 . The masses of all these candidates are in good agreement with Bag Model predictions. A hypercharge selection rule is suggested: ''The hypercharge of hadronic resonances in weak gravitational fields cannot exceed one Y <= 1

  9. Stochastic resonance

    International Nuclear Information System (INIS)

    Wellens, Thomas; Shatokhin, Vyacheslav; Buchleitner, Andreas

    2004-01-01

    We are taught by conventional wisdom that the transmission and detection of signals is hindered by noise. However, during the last two decades, the paradigm of stochastic resonance (SR) proved this assertion wrong: indeed, addition of the appropriate amount of noise can boost a signal and hence facilitate its detection in a noisy environment. Due to its simplicity and robustness, SR has been implemented by mother nature on almost every scale, thus attracting interdisciplinary interest from physicists, geologists, engineers, biologists and medical doctors, who nowadays use it as an instrument for their specific purposes. At the present time, there exist a lot of diversified models of SR. Taking into account the progress achieved in both theoretical understanding and practical application of this phenomenon, we put the focus of the present review not on discussing in depth technical details of different models and approaches but rather on presenting a general and clear physical picture of SR on a pedagogical level. Particular emphasis will be given to the implementation of SR in generic quantum systems-an issue that has received limited attention in earlier review papers on the topic. The major part of our presentation relies on the two-state model of SR (or on simple variants thereof), which is general enough to exhibit the main features of SR and, in fact, covers many (if not most) of the examples of SR published so far. In order to highlight the diversity of the two-state model, we shall discuss several examples from such different fields as condensed matter, nonlinear and quantum optics and biophysics. Finally, we also discuss some situations that go beyond the generic SR scenario but are still characterized by a constructive role of noise

  10. Predicting Collateral Status With Magnetic Resonance Perfusion Parameters: Probabilistic Approach With a Tmax-Derived Prediction Model.

    Science.gov (United States)

    Lee, Mi Ji; Son, Jeong Pyo; Kim, Suk Jae; Ryoo, Sookyung; Woo, Sook-Young; Cha, Jihoon; Kim, Gyeong-Moon; Chung, Chin-Sang; Lee, Kwang Ho; Bang, Oh Young

    2015-10-01

    Good collateral flow is an important predictor for favorable responses to recanalization therapy and successful outcomes after acute ischemic stroke. Magnetic resonance perfusion-weighted imaging (MRP) is widely used in patients with stroke. However, it is unclear whether the perfusion parameters and thresholds would predict collateral status. The present study evaluated the relationship between hypoperfusion severity and collateral status to develop a predictive model for good collaterals using MRP parameters. Patients who were eligible for recanalization therapy that underwent both serial diffusion-weighted imaging and serial MRP were enrolled into the study. A collateral flow map derived from MRP source data was generated through automatic postprocessing. Hypoperfusion severity, presented as proportions of every 2-s Tmax strata to the entire hypoperfusion volume (Tmax≥2 s), was compared between patients with good and poor collaterals. Prediction models for good collaterals were developed with each Tmax strata proportion and cerebral blood volumes. Among 66 patients, 53 showed good collaterals based on MRP-based collateral grading. Although no difference was noted in delays within 16 s, more severe Tmax delays (Tmax16-18 s, Tmax18-22 s, Tmax22-24 s, and Tmax>24 s) were associated with poor collaterals. The probability equation model using Tmax strata proportion demonstrated high predictive power in a receiver operating characteristic analysis (area under the curve=0.9303; 95% confidence interval, 0.8682-0.9924). The probability score was negatively correlated with the volume of infarct growth (P=0.030). Collateral status is associated with more severe Tmax delays than previously defined. The present Tmax severity-weighted model can determine good collaterals and subsequent infarct growth. © 2015 American Heart Association, Inc.

  11. Establishing magnetic resonance imaging as an accurate and reliable tool to diagnose and monitor esophageal cancer in a rat model.

    Directory of Open Access Journals (Sweden)

    Juliann E Kosovec

    Full Text Available OBJECTIVE: To assess the reliability of magnetic resonance imaging (MRI for detection of esophageal cancer in the Levrat model of end-to-side esophagojejunostomy. BACKGROUND: The Levrat model has proven utility in terms of its ability to replicate Barrett's carcinogenesis by inducing gastroduodenoesophageal reflux (GDER. Due to lack of data on the utility of non-invasive methods for detection of esophageal cancer, treatment efficacy studies have been limited, as adenocarcinoma histology has only been validated post-mortem. It would therefore be of great value if the validity and reliability of MRI could be established in this setting. METHODS: Chronic GDER reflux was induced in 19 male Sprague-Dawley rats using the modified Levrat model. At 40 weeks post-surgery, all animals underwent endoscopy, MRI scanning, and post-mortem histological analysis of the esophagus and anastomosis. With post-mortem histology serving as the gold standard, assessment of presence of esophageal cancer was made by five esophageal specialists and five radiologists on endoscopy and MRI, respectively. RESULTS: The accuracy of MRI and endoscopic analysis to correctly identify cancer vs. no cancer was 85.3% and 50.5%, respectively. ROC curves demonstrated that MRI rating had an AUC of 0.966 (p<0.001 and endoscopy rating had an AUC of 0.534 (p = 0.804. The sensitivity and specificity of MRI for identifying cancer vs. no-cancer was 89.1% and 80% respectively, as compared to 45.5% and 57.5% for endoscopy. False positive rates of MRI and endoscopy were 20% and 42.5%, respectively. CONCLUSIONS: MRI is a more reliable diagnostic method than endoscopy in the Levrat model. The non-invasiveness of the tool and its potential to volumetrically quantify the size and number of tumors likely makes it even more useful in evaluating novel agents and their efficacy in treatment studies of esophageal cancer.

  12. Registration-based segmentation with articulated model from multipostural magnetic resonance images for hand bone motion animation.

    Science.gov (United States)

    Chen, Hsin-Chen; Jou, I-Ming; Wang, Chien-Kuo; Su, Fong-Chin; Sun, Yung-Nien

    2010-06-01

    The quantitative measurements of hand bones, including volume, surface, orientation, and position are essential in investigating hand kinematics. Moreover, within the measurement stage, bone segmentation is the most important step due to its certain influences on measuring accuracy. Since hand bones are small and tubular in shape, magnetic resonance (MR) imaging is prone to artifacts such as nonuniform intensity and fuzzy boundaries. Thus, greater detail is required for improving segmentation accuracy. The authors then propose using a novel registration-based method on an articulated hand model to segment hand bones from multipostural MR images. The proposed method consists of the model construction and registration-based segmentation stages. Given a reference postural image, the first stage requires construction of a drivable reference model characterized by hand bone shapes, intensity patterns, and articulated joint mechanism. By applying the reference model to the second stage, the authors initially design a model-based registration pursuant to intensity distribution similarity, MR bone intensity properties, and constraints of model geometry to align the reference model to target bone regions of the given postural image. The authors then refine the resulting surface to improve the superimposition between the registered reference model and target bone boundaries. For each subject, given a reference postural image, the proposed method can automatically segment all hand bones from all other postural images. Compared to the ground truth from two experts, the resulting surface image had an average margin of error within 1 mm (mm) only. In addition, the proposed method showed good agreement on the overlap of bone segmentations by dice similarity coefficient and also demonstrated better segmentation results than conventional methods. The proposed registration-based segmentation method can successfully overcome drawbacks caused by inherent artifacts in MR images and

  13. Application of Finite Element Modeling Methods in Magnetic Resonance Imaging-Based Research and Clinical Management

    Science.gov (United States)

    Fwu, Peter Tramyeon

    The medical image is very complex by its nature. Modeling built upon the medical image is challenging due to the lack of analytical solution. Finite element method (FEM) is a numerical technique which can be used to solve the partial differential equations. It utilized the transformation from a continuous domain into solvable discrete sub-domains. In three-dimensional space, FEM has the capability dealing with complicated structure and heterogeneous interior. That makes FEM an ideal tool to approach the medical-image based modeling problems. In this study, I will address the three modeling in (1) photon transport inside the human breast by implanting the radiative transfer equation to simulate the diffuse optical spectroscopy imaging (DOSI) in order to measurement the percent density (PD), which has been proven as a cancer risk factor in mammography. Our goal is to use MRI as the ground truth to optimize the DOSI scanning protocol to get a consistent measurement of PD. Our result shows DOSI measurement is position and depth dependent and proper scanning scheme and body configuration are needed; (2) heat flow in the prostate by implementing the Penne's bioheat equation to evaluate the cooling performance of regional hypothermia during the robot assisted radical prostatectomy for the individual patient in order to achieve the optimal cooling setting. Four factors are taken into account during the simulation: blood abundance, artery perfusion, cooling balloon temperature, and the anatomical distance. The result shows that blood abundance, prostate size, and anatomical distance are significant factors to the equilibrium temperature of neurovascular bundle; (3) shape analysis in hippocampus by using the radial distance mapping, and two registration methods to find the correlation between sub-regional change to the age and cognition performance, which might not reveal in the volumetric analysis. The result gives a fundamental knowledge of normal distribution in young

  14. Application of Benchtop-magnetic resonance imaging in a nude mouse tumor model

    Directory of Open Access Journals (Sweden)

    Mäder Karsten

    2011-07-01

    Full Text Available Abstract Background MRI plays a key role in the preclinical development of new drugs, diagnostics and their delivery systems. However, very high installation and running costs of existing superconducting MRI machines limit the spread of MRI. The new method of Benchtop-MRI (BT-MRI has the potential to overcome this limitation due to much lower installation and almost no running costs. However, due to the low field strength and decreased magnet homogeneity it is questionable, whether BT-MRI can achieve sufficient image quality to provide useful information for preclinical in vivo studies. It was the aim of the current study to explore the potential of BT-MRI on tumor models in mice. Methods We used a prototype of an in vivo BT-MRI apparatus to visualise organs and tumors and to analyse tumor progression in nude mouse xenograft models of human testicular germ cell tumor and colon carcinoma. Results Subcutaneous xenografts were easily identified as relative hypointense areas in transaxial slices of NMR images. Monitoring of tumor progression evaluated by pixel extension analyses based on NMR images correlated with increasing tumor volume calculated by calliper measurement. Gd-BOPTA contrast agent injection resulted in a better differentiation between parts of the urinary tissues and organs due to fast elimination of the agent via kidneys. In addition, interior structuring of tumors could be observed. A strong contrast enhancement within a tumor was associated with a central necrotic/fibrotic area. Conclusions BT-MRI provides satisfactory image quality to visualize organs and tumors and to monitor tumor progression and structure in mouse models.

  15. Nonlinear resonances

    CERN Document Server

    Rajasekar, Shanmuganathan

    2016-01-01

    This introductory text presents the basic aspects and most important features of various types of resonances and anti-resonances in dynamical systems. In particular, for each resonance, it covers the theoretical concepts, illustrates them with case studies, and reviews the available information on mechanisms, characterization, numerical simulations, experimental realizations, possible quantum analogues, applications and significant advances made over the years. Resonances are one of the most fundamental phenomena exhibited by nonlinear systems and refer to specific realizations of maximum response of a system due to the ability of that system to store and transfer energy received from an external forcing source. Resonances are of particular importance in physical, engineering and biological systems - they can prove to be advantageous in many applications, while leading to instability and even disasters in others. The book is self-contained, providing the details of mathematical derivations and techniques invo...

  16. Modeling of ITER edge plasma in the presence of resonant magnetic perturbations

    Energy Technology Data Exchange (ETDEWEB)

    Rozhansky, V.; Kaveeva, E.; Veselova, I.; Voskoboynikov, S. [Peter the Great St. Petersburg Polytechnic University, St. Petersburg (Russian Federation); Coster, D. [Max-Planck Institut fur Plasmaphysik, EURATOM Association, Garching (Germany)

    2016-08-15

    The modeling of the ITER edge is performed with the use of the code B2SOLPS5.2 in the presence of the electron conductivity caused by RMPs as well as for the reference case with the same input parameters but without RMPs. The radial electric field close to the neoclassical one is obtained without RMPs. Even the modest level of RMPs changes the direction of the electric field and causes the toroidal spin-up of the edge plasma. At the same time the pump-out effect is small. (copyright 2016 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  17. bantib-production on the Z resonance: a challenge to the standard model

    International Nuclear Information System (INIS)

    Djouadi, A.; Renard, F.M.; Girardi, G.; Verzegnassi, C.

    1990-04-01

    We study the potentialities for exposing physics beyond the standard model that are offered by accurate measurements of the process Z → bantib in a high luminosity phase at LEP. In particular we propose a strategy by defining observables in such a way that they are separately sensitive to different kinds of New Physics. This approach enables us to show that with 10 7 - 10 8 produced bantib pairs one may either obtain very stringent bounds on the extra neutral gauge bosons sector, or identify it unambiguously. Also, it appears that Z → bantib provides under those circumstances a privileged tool to reveal clean virtual effects of supersymmetry

  18. Understanding and modeling Förster-type resonance energy transfer (FRET)

    CERN Document Server

    Hernández Martínez, Pedro Ludwig; Demir, Hilmi Volkan

    2017-01-01

    This Brief presents a complete study of the generalized theory of Förster-type energy transfer in nanostructures with mixed dimensionality. Here the aim is to obtain a generalized theory of FRET including a comprehensive set of analytical equations for all combinations and configurations of nanostructures and deriving generic expressions for the dimensionality involved. In this brief, the modification of FRET mechanism with respect to the nanostructure serving as the donor vs. the acceptor will be included, focusing on the rate’s distance dependency and the role of the effective dielectric function in FRET, which will be a unique, useful source for those who study and model FRET.

  19. Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation.

    Directory of Open Access Journals (Sweden)

    Douglas D Fang

    Full Text Available PIK3CA (phosphoinositide-3-kinase, catalytic, alpha polypeptide mutations can help predict the antitumor activity of phosphatidylinositol-3-kinase (PI3K/mammalian target of rapamycin (mTOR pathway inhibitors in both preclinical and clinical settings. In light of the recent discovery of tumor-initiating cancer stem cells (CSCs in various tumor types, we developed an in vitro CSC model from xenograft tumors established in mice from a colorectal cancer patient tumor in which the CD133+/EpCAM+ population represented tumor-initiating cells. CD133+/EpCAM+ CSCs were enriched under stem cell culture conditions and formed 3-dimensional tumor spheroids. Tumor spheroid cells exhibited CSC properties, including the capability for differentiation and self-renewal, higher tumorigenic potential and chemo-resistance. Genetic analysis using an OncoCarta™ panel revealed a PIK3CA (H1047R mutation in these cells. Using a dual PI3K/mTOR inhibitor, PF-04691502, we then showed that blockage of the PI3K/mTOR pathway inhibited the in vitro proliferation of CSCs and in vivo xenograft tumor growth with manageable toxicity. Tumor growth inhibition in mice was accompanied by a significant reduction of phosphorylated Akt (pAKT (S473, a well-established surrogate biomarker of PI3K/mTOR signaling pathway inhibition. Collectively, our data suggest that PF-04691502 exhibits potent anticancer activity in colorectal cancer by targeting both PIK3CA (H1047R mutant CSCs and their derivatives. These results may assist in the clinical development of PF-04691502 for the treatment of a subpopulation of colorectal cancer patients with poor outcomes.

  20. Mathematical modeling of a four-stroke resonant engine for micro and mesoscale applications

    Science.gov (United States)

    Preetham, B. S.; Anderson, M.; Richards, C.

    2014-12-01

    In order to mitigate frictional and leakage losses in small scale engines, a compliant engine design is proposed in which the piston in cylinder arrangement is replaced by a flexible cavity. A physics-based nonlinear lumped-parameter model is derived to predict the performance of a prototype engine. The model showed that the engine performance depends on input parameters, such as heat input, heat loss, and load on the engine. A sample simulation for a reference engine with octane fuel/air ratio of 0.043 resulted in an indicated thermal efficiency of 41.2%. For a fixed fuel/air ratio, higher output power is obtained for smaller loads and vice-versa. The heat loss from the engine and the work done on the engine during the intake stroke are found to decrease the indicated thermal efficiency. The ratio of friction work to indicated work in the prototype engine is about 8%, which is smaller in comparison to the traditional reciprocating engines.

  1. Exploiting magnetic resonance angiography imaging improves model estimation of BOLD signal.

    Directory of Open Access Journals (Sweden)

    Zhenghui Hu

    Full Text Available The change of BOLD signal relies heavily upon the resting blood volume fraction ([Formula: see text] associated with regional vasculature. However, existing hemodynamic data assimilation studies pretermit such concern. They simply assign the value in a physiologically plausible range to get over ill-conditioning of the assimilation problem and fail to explore actual [Formula: see text]. Such performance might lead to unreliable model estimation. In this work, we present the first exploration of the influence of [Formula: see text] on fMRI data assimilation, where actual [Formula: see text] within a given cortical area was calibrated by an MR angiography experiment and then was augmented into the assimilation scheme. We have investigated the impact of [Formula: see text] on single-region data assimilation and multi-region data assimilation (dynamic cause modeling, DCM in a classical flashing checkerboard experiment. Results show that the employment of an assumed [Formula: see text] in fMRI data assimilation is only suitable for fMRI signal reconstruction and activation detection grounded on this signal, and not suitable for estimation of unobserved states and effective connectivity study. We thereby argue that introducing physically realistic [Formula: see text] in the assimilation process may provide more reliable estimation of physiological information, which contributes to a better understanding of the underlying hemodynamic processes. Such an effort is valuable and should be well appreciated.

  2. Early magnetic resonance imaging and histologic findings in a model of avascular necrosis of femoral head

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, Takuya [Kanazawa Univ. (Japan). School of Medicine

    1997-12-01

    The present study was performed to examine early MR images and histologic findings using a canine model of avascular necrosis of femoral head (ANFH). The ANFH model was surgically induced. At three days, 1, 2 and 4 weeks after surgery, the proximal femurs were excised. MR images were obtained in 4 dogs at 3 days and 7 dogs at each of the other intervals. Histologic examinations were performed on 7 dogs at each interval. Three days after surgery, MR showed almost no abnormal findings. Histologic changes included edematous bone marrow and bleeding in the bone marrow in some regions. One week after surgery, empty lacunae in trabecular bones and immature fibrous tissues in the bone marrow were seen in some cases, but appositional bone was not yet apparent. In only one case, abnormal MR findings -a ringlike pattern- were seen. Two weeks after surgery, 4 cases showed appositional bones on histology and abnormalities on MR images. Four weeks after surgery, fibrous tissues had matured and appositional bones had increased. Therefore, all 7 cases showed MR imaging abnormalities. Abnormal MR images included a ringlike pattern, and homogeneous and inhomogeneous patterns. These results indicated that MR imaging shows abnormality 2 weeks after surgery at the latest. (author)

  3. Models of the Dynamics of Spatially Separated Broadband Electromagnetic Fields Interacting with Resonant Atoms

    Science.gov (United States)

    Basharov, A. M.

    2018-03-01

    The Markov model of spontaneous emission of an atom localized in a spatial region with a broadband electromagnetic field with zero photon density is considered in the conditions of coupling of the electromagnetic field with the broadband field of a neighboring space. The evolution operator of the system and the kinetic equation for the atom are obtained. It is shown that the field coupling constant affects the rate of spontaneous emission of the atom, but is not manifested in the atomic frequency shift. The analytic expression for the radiative decay constant for the atom is found to be analogous in a certain sense to the expression for the decay constant for a singly excited localized ensemble of identical atoms in the conditions when the effect of stabilization of its excited state by the Stark interaction with the vacuum broadband electromagnetic field is manifested. The model is formulated based on quantum stochastic differential equations of the non- Wiener type and the generalized algebra of the Ito differential of quantum random processes.

  4. Dynamic contrast-enhanced magnetic resonance imaging and pharmacokinetic models in prostate cancer

    International Nuclear Information System (INIS)

    Franiel, Tobias; Hamm, Bernd; Hricak, Hedvig

    2011-01-01

    Dynamic contrast-enhanced MRI enables noninvasive analysis of prostate vascularization as well as tumour angiogenesis and capillary permeability characteristics in prostate cancers. Pharmacokinetic models summarizing the complex information provided by signal intensity-time curves for a few quantitative pharmacokinetic parameters are increasingly being used in the routine clinical setting. This review consists of two parts. The first part discusses the advantages and disadvantages of the MR pulse sequences that can be used for performing DCE-MRI and also of the most widely used pharmacokinetic parameters and models and the parameters they describe. The second part outlines the range of current and potential future clinical applications of DCE-MRI and pharmacokinetic parametric maps in patients with prostate cancer, with reference to the current scientific literature on the topic. The potential clinical applications of DCE-MRI for prostate cancer include detection, localization, and staging, differentiation of recurrent cancer and estimation of the patient's prognosis, as well as monitoring of treatment response. (orig.)

  5. Selecting the optimum engineering model for the frequency response of fcc nanowire resonators

    DEFF Research Database (Denmark)

    Nasr Esfahani, M.; Yilmaz, M.; Sonne, Mads Rostgaard

    2017-01-01

    of extreme surface-to-volume ratios remains question- able. Classical finite element method can partially be used to address these deficiencies. On the other hand, molecular dynamics provide accurate results, while nanowire geome- tries studied with this computationally demanding technique usually remain...... confined to dimensions below those of practical interest. To address these issues, a benchmarking study among analytical and numerical techniques is carried out, where Surface Cauchy–Born theory serves as the reference. Using gold nanowires with different dimensions and boundary conditions, it is observed......-to-thickness ratios exceeding 11 for both the analytical approach and the classical finite element method in the fixed–fixed structure. The deviations are quantitatively linked to the dominance of the surface effect through the use of the Surface Cauchy–Born model. For length-to-thickness ratios less than 7, the lack...

  6. Description of dispersion properties of metals by means of the critical points model and application to the study of resonant structures using the FDTD method

    Energy Technology Data Exchange (ETDEWEB)

    Vial, Alexandre; Laroche, Thierry [Institut Charles Delaunay, Universite de Technologie de Troyes, CNRS FRE 2848, Laboratoire de Nanotechnologie et d' Instrumentation Optique 12, rue Marie Curie, BP-2060, F-10010 Troyes Cedex (France)

    2007-11-21

    Using a combination of Drude and critical points models, we show that the permittivity of several metals can be more efficiently described than using the well-known Drude-Lorentz model. The numerical implementation in a finite-difference time-domain code together with a non-uniform grid enables the study of thin metallic intermediate layers often neglected in simulations but found in realistic resonant structures.

  7. MO-F-CAMPUS-I-04: Magnetic Resonance Imaging of An in Vitro 3D Tumor Model

    International Nuclear Information System (INIS)

    Veiga, C; Long, T; Siow, B; Loizidou, M; Royle, G; Ricketts, K

    2015-01-01

    Purpose: To investigate the use of an in vitro 3D tumor model (tumoroid) as a bio-phantom for repetitive and sequential magnetic resonance imaging (MRI) studies. Methods: The tissue engineered tumoroid comprised an artificial cancer mass (ACM) containing 30 million HT29 cancer cells seeded in a collagen type I matrix, whose density was increased by plastic compression (dry/wet weight=40%). The ACM was embedded in an uncompressed collagen gel that mimicked the tumor stroma, and the tumoroid was incubated for 24h before imaging. Images were acquired using the 1T ICON™ (Bruker Corporation, Billerica, MA) MRI scanner. T1 maps were calculated using an IR-RARE sequence (TE=12ms, TR=10000ms, 7 inversion times), while for T2 maps a MSME technique (TR=6000ms, 16 echoes) was used. T1 and T2 fittings were performed using a pixel-wise approach to produce relaxometric parametric maps. Results: The images acquired and corresponding T1 and T2 maps indicate contrast between the ACM and the stroma. T1 was 2500 and 2800ms, while T2 was 520 and 760ms, for the ACM and stroma respectively. The ACM construct was not homogenous and internal features were visible, which can be explained by local gradients of cell and/or collagen density. The viability of the cells was confirmed via confocal microscopy for several days after the imaging session, demonstrating the suitability of the tumoroid for sequential imaging studies. Conclusions: We have engineered a tumor model compatible with repetitive and sequential MRI. We found T1 and T2 contrast between the ACM and stroma using a pre-clinical MRI scanner. The model, which enables controllable cell and matrix densities, has potential for a wide range of applications in radiotherapy, such as to study tumor progression and to validate imaging biomarkers. Further work is necessary to understand the mechanisms behind the contrast achieved, and to correlate findings with biology and histology data

  8. MO-F-CAMPUS-I-04: Magnetic Resonance Imaging of An in Vitro 3D Tumor Model

    Energy Technology Data Exchange (ETDEWEB)

    Veiga, C; Long, T; Siow, B; Loizidou, M; Royle, G; Ricketts, K [University College London, London (United Kingdom)

    2015-06-15

    Purpose: To investigate the use of an in vitro 3D tumor model (tumoroid) as a bio-phantom for repetitive and sequential magnetic resonance imaging (MRI) studies. Methods: The tissue engineered tumoroid comprised an artificial cancer mass (ACM) containing 30 million HT29 cancer cells seeded in a collagen type I matrix, whose density was increased by plastic compression (dry/wet weight=40%). The ACM was embedded in an uncompressed collagen gel that mimicked the tumor stroma, and the tumoroid was incubated for 24h before imaging. Images were acquired using the 1T ICON™ (Bruker Corporation, Billerica, MA) MRI scanner. T1 maps were calculated using an IR-RARE sequence (TE=12ms, TR=10000ms, 7 inversion times), while for T2 maps a MSME technique (TR=6000ms, 16 echoes) was used. T1 and T2 fittings were performed using a pixel-wise approach to produce relaxometric parametric maps. Results: The images acquired and corresponding T1 and T2 maps indicate contrast between the ACM and the stroma. T1 was 2500 and 2800ms, while T2 was 520 and 760ms, for the ACM and stroma respectively. The ACM construct was not homogenous and internal features were visible, which can be explained by local gradients of cell and/or collagen density. The viability of the cells was confirmed via confocal microscopy for several days after the imaging session, demonstrating the suitability of the tumoroid for sequential imaging studies. Conclusions: We have engineered a tumor model compatible with repetitive and sequential MRI. We found T1 and T2 contrast between the ACM and stroma using a pre-clinical MRI scanner. The model, which enables controllable cell and matrix densities, has potential for a wide range of applications in radiotherapy, such as to study tumor progression and to validate imaging biomarkers. Further work is necessary to understand the mechanisms behind the contrast achieved, and to correlate findings with biology and histology data.

  9. Harbor seal vibrissa morphology suppresses vortex-induced vibrations.

    Science.gov (United States)

    Hanke, Wolf; Witte, Matthias; Miersch, Lars; Brede, Martin; Oeffner, Johannes; Michael, Mark; Hanke, Frederike; Leder, Alfred; Dehnhardt, Guido

    2010-08-01

    Harbor seals (Phoca vitulina) often live in dark and turbid waters, where their mystacial vibrissae, or whiskers, play an important role in orientation. Besides detecting and discriminating objects by direct touch, harbor seals use their whiskers to analyze water movements, for example those generated by prey fish or by conspecifics. Even the weak water movements left behind by objects that have passed by earlier can be sensed and followed accurately (hydrodynamic trail following). While scanning the water for these hydrodynamic signals at a swimming speed in the order of meters per second, the seal keeps its long and flexible whiskers in an abducted position, largely perpendicular to the swimming direction. Remarkably, the whiskers of harbor seals possess a specialized undulated surface structure, the function of which was, up to now, unknown. Here, we show that this structure effectively changes the vortex street behind the whiskers and reduces the vibrations that would otherwise be induced by the shedding of vortices from the whiskers (vortex-induced vibrations). Using force measurements, flow measurements and numerical simulations, we find that the dynamic forces on harbor seal whiskers are, by at least an order of magnitude, lower than those on sea lion (Zalophus californianus) whiskers, which do not share the undulated structure. The results are discussed in the light of pinniped sensory biology and potential biomimetic applications.

  10. 78 FR 63381 - Safety Zones; Hawaiian Island Commercial Harbors, HI

    Science.gov (United States)

    2013-10-24

    ...; Kaumalapau, Lanai; Kahului, Maui and Kawaihae and Hilo on the Island of Hawaii). The purpose of these safety... the piers faces. (9) All waters of Hilo Harbor, Hawaii immediately adjacent to commercial piers 1 and.... SUMMARY: The Coast Guard is establishing nine (9) permanent safety zones encompassing Hawaii's commercial...

  11. 33 CFR 117.181 - Oakland Inner Harbor Tidal Canal.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Oakland Inner Harbor Tidal Canal. 117.181 Section 117.181 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY... Tidal Canal. The draws of the Alameda County highway drawbridges at Park Street, mile 5.2; Fruitvale...

  12. 78 FR 21597 - Marine Mammals: Alaska Harbor Seal Habitats

    Science.gov (United States)

    2013-04-11

    ... seek input as to whether management measures are needed, and if so, what types of measures should be... proposed rulemaking (ANPR) on potential management measures to protect glacially-associated harbor seal... need for regulations; (2) the geographic scope and time horizon of regulations; (3) management options...

  13. Quantitative Measures of Anthropogenic Noise on Harbor Porpoises

    DEFF Research Database (Denmark)

    Wisniewska, Danuta Maria; Teilmann, Jonas; Hermannsen, Line

    2016-01-01

    -animal recordings as proxies for actual exposure. Here, we quantify sound exposure levels recorded with a DTAG-3 tag on a captive harbor porpoise exposed to vessel noise in a controlled acoustic environment. Results show that fl ow noise is limiting onboard noise recordings, whereas no evidence of body shading has...

  14. Rhizosphere of rice plants harbor bacteria with multiple plant growth ...

    African Journals Online (AJOL)

    Rhizosphere of rice plants harbor bacteria with multiple plant growth promoting features. ... 45 (39.46%) isolates were capable of producing siderophore, the range of production being 4.50 to 223.26 μg mg-1 protein. Analysis of molecular diversity was made by amplified ribosomal DNA restriction analysis (ARDRA) and ...

  15. U.S. Department of Defense - Pearl Harbor Special

    Science.gov (United States)

    Hawaii saw that seminal moment in history, and those that were there vividly remember that Sunday morning this noise," he said in an oral history on the Pearl Harbor Survivors' Association Web site. " seeing was an attack. "It didn't mean anything to us until a large group of planes came near the

  16. Clearance and Biodistribution of Liposomally Encapsulated Nitroxides: A Model for Targeted Delivery of Electron Paramagnetic Resonance Imaging Probes to Tumors

    Science.gov (United States)

    Burks, Scott R.; Legenzov, Eric A.; Rosen, Gerald M.

    2011-01-01

    Electron paramagnetic resonance (EPR) imaging using nitroxides as molecular probes is potentially a powerful tool for the detection and physiological characterization of micrometastatic lesions. Encapsulating nitroxides in anti-HER2 immunoliposomes at high concentrations to take advantage of the “self-quenching” phenomenon of nitroxides allows generation of robust EPR signals in HER2-overexpressing breast tumor cells with minimal background from indifferent tissues or circulating liposomes. We investigated the in vivo pharmacological properties of nitroxides encapsulated in sterically stabilized liposomes designed for long circulation times. We show that circulation times of nitroxides can be extended from hours to days; this increases the proportion of liposomes in circulation to enhance tumor targeting. Furthermore, nitroxides encapsulated in sterically stabilized anti-HER2 immunoliposomes can be delivered to HER2-overexpressing tumors at micromolar concentrations, which should be imageable by EPR. Lastly, after in vivo administration, liposomally encapsulated nitroxide signal also appears in the liver, spleen, and kidneys. Although these organs are spatially distinct and would not hinder tumor imaging in our model, understanding nitroxide signal retention in these organs is essential for further improvements in EPR imaging contrast between tumors and other tissues. These results lay the foundation to use liposomally delivered nitroxides and EPR imaging to visualize tumor cells in vivo. PMID:21737567

  17. Longitudinal diffusion tensor magnetic resonance imaging study of radiation-induced white matter damage in a rat model.

    Science.gov (United States)

    Wang, Silun; Wu, Ed X; Qiu, Deqiang; Leung, Lucullus H T; Lau, Ho-Fai; Khong, Pek-Lan

    2009-02-01

    Radiation-induced white matter (WM) damage is a major side effect of whole brain irradiation among childhood cancer survivors. We evaluate longitudinally the diffusion characteristics of the late radiation-induced WM damage in a rat model after 25 and 30 Gy irradiation to the hemibrain at 8 time points from 2 to 48 weeks postradiation. We hypothesize that diffusion tensor magnetic resonance imaging (DTI) indices including fractional anisotropy (FA), trace, axial diffusivity (lambda(//)), and radial diffusivity (lambda( perpendicular)) can accurately detect and monitor the histopathologic changes of radiation-induced WM damage, measured at the EC, and that these changes are dose and time dependent. Results showed a progressive reduction of FA, which was driven by reduction in lambda(//) from 4 to 40 weeks postradiation, and an increase in lambda( perpendicular) with return to baseline in lambda(//) at 48 weeks postradiation. Histologic evaluation of irradiated WM showed reactive astrogliosis from 4 weeks postradiation with reversal at 36 weeks, and demyelination, axonal degeneration, and necrosis at 48 weeks postradiation. Moreover, changes in lambda(//) correlated with reactive astrogliosis (P histopathologic changes of WM damage and our results support the use of DTI as a biomarker to noninvasively monitor radiation-induced WM damage.

  18. Magnetic resonance imaging and tensor-based morphometry in the MPTP non-human primate model of Parkinson's disease.

    Directory of Open Access Journals (Sweden)

    Michel Modo

    Full Text Available Parkinson's disease (PD is the second most common neurodegenerative disorder producing a variety of motor and cognitive deficits with the causes remaining largely unknown. The gradual loss of the nigrostriatal pathway is currently considered the pivotal pathological event. To better understand the progression of PD and improve treatment management, defining the disease on a structural basis and expanding brain analysis to extra-nigral structures is indispensable. The anatomical complexity and the presence of neuromelanin, make the use of non-human primates an essential element in developing putative imaging biomarkers of PD. To this end, ex vivo T2-weighted magnetic resonance images were acquired from control and 1-methyl-4 phenyl-1,2,3,6-tetrahydropyridine (MPTP-treated marmosets. Volume measurements of the caudate, putamen, and substantia nigra indicated significant atrophy and cortical thinning. Tensor-based morphometry provided a more extensive and hypothesis free assessment of widespread changes caused by the toxin insult to the brain, especially highlighting regional cortical atrophy. The results highlight the importance of developing imaging biomarkers of PD in non-human primate models considering their distinct neuroanatomy. It is essential to further develop these biomarkers in vivo to provide non-invasive tools to detect pre-symptomatic PD and to monitor potential disease altering therapeutics.

  19. Magnetic resonance imaging and tensor-based morphometry in the MPTP non-human primate model of Parkinson's disease.

    Science.gov (United States)

    Modo, Michel; Crum, William R; Gerwig, Madeline; Vernon, Anthony C; Patel, Priya; Jackson, Michael J; Rose, Sarah; Jenner, Peter; Iravani, Mahmoud M

    2017-01-01

    Parkinson's disease (PD) is the second most common neurodegenerative disorder producing a variety of motor and cognitive deficits with the causes remaining largely unknown. The gradual loss of the nigrostriatal pathway is currently considered the pivotal pathological event. To better understand the progression of PD and improve treatment management, defining the disease on a structural basis and expanding brain analysis to extra-nigral structures is indispensable. The anatomical complexity and the presence of neuromelanin, make the use of non-human primates an essential element in developing putative imaging biomarkers of PD. To this end, ex vivo T2-weighted magnetic resonance images were acquired from control and 1-methyl-4 phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated marmosets. Volume measurements of the caudate, putamen, and substantia nigra indicated significant atrophy and cortical thinning. Tensor-based morphometry provided a more extensive and hypothesis free assessment of widespread changes caused by the toxin insult to the brain, especially highlighting regional cortical atrophy. The results highlight the importance of developing imaging biomarkers of PD in non-human primate models considering their distinct neuroanatomy. It is essential to further develop these biomarkers in vivo to provide non-invasive tools to detect pre-symptomatic PD and to monitor potential disease altering therapeutics.

  20. Modeling of divertor particle and heat loads during application of resonant magnetic perturbation fields for ELM control in ITER

    Energy Technology Data Exchange (ETDEWEB)

    Schmitz, O., E-mail: o.schmitz@fz-juelich.de [Forschungszentrum Jülich, IEK-4, Association EURATOM-FZJ, Jülich (Germany); Becoulet, M. [CEA/IRFM, Cadarache, 13108 St. Paul-lez-Durance Cedex (France); Cahyna, P. [IPP AS CR, Za Slovankou 3, 18200 Prague 8 (Czech Republic); Evans, T.E. [General Atomics, P.O. Box 85608, San Diego, CA 92186-5608 (United States); Feng, Y. [Max-Planck-Institut für Plasmaphysik, Greifswald (Germany); Frerichs, H.; Kirschner, A. [Forschungszentrum Jülich, IEK-4, Association EURATOM-FZJ, Jülich (Germany); Kukushkin, A. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Laengner, R. [Forschungszentrum Jülich, IEK-4, Association EURATOM-FZJ, Jülich (Germany); Lunt, T. [Max-Planck-Institut für Plasmaphysik, Greifswald (Germany); Loarte, A.; Pitts, R. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul Lez Durance (France); Reiser, D.; Reiter, D. [Forschungszentrum Jülich, IEK-4, Association EURATOM-FZJ, Jülich (Germany); Saibene, G. [Fusion for Energy Joint Undertaking, Barcelona (Spain); Samm, U. [Forschungszentrum Jülich, IEK-4, Association EURATOM-FZJ, Jülich (Germany)

    2013-07-15

    First results from three-dimensional modeling of the divertor heat and particle flux pattern during application of resonant magnetic perturbation fields as ELM control scheme in ITER with the EMC3-Eirene fluid plasma and kinetic neutral transport code are discussed. The formation of a helical magnetic footprint breaks the toroidal symmetry of the heat and particle fluxes. Expansion of the flux pattern as far as 60 cm away from the unperturbed strike line is seen with vacuum RMP fields, resulting in a preferable heat flux spreading. Inclusion of plasma response reduces the radial extension of the heat and particle fluxes and results in a heat flux peaking closer to the unperturbed level. A strong reduction of the particle confinement is found. 3D flow channels are identified as a consistent reason due to direct parallel outflow from inside of the separatrix. Their radial inward expansion and hence the level of particle pump out is shown to be dependent on the perturbation level.

  1. In vivo detection of c-MET expression in a rat hepatocarcinogenesis model using molecularly targeted magnetic resonance imaging.

    Science.gov (United States)

    Towner, Rheal A; Smith, Nataliya; Tesiram, Yasvir A; Abbott, Andrew; Saunders, Debbie; Blindauer, Rebecca; Herlea, Oana; Silasi-Mansat, Robert; Lupu, Florea

    2007-01-01

    The multifunctional growth factor scatter factor/hepatocyte growth factor and its tyrosine kinase receptor, c-MET, have been implicated in the genesis and malignant progression of numerous human malignancies, including hepatocellular carcinomas. The incidence of hepatocellular carcinomas in the United States has increased noticeably over the past two decades and is listed as the fifth major cancer in men worldwide. In this study, we used a choline-deficient l-amino acid (CDAA)-defined rat hepatocarcinogenesis model to visualize increased in vivo expression of the c-MET antigen in neoplastic lesion formation with the use of a super paramagnetic iron oxide (SPIO)-anti-c-MET molecularly targeted magnetic resonance imaging (MRI) contrast agent. SPIO-anti-c-MET was used for the first time to detect overexpression of c-MET in neoplastic nodules and tumors within the livers of CDAA-treated rats, as determined by a decrease in MRI signal intensity and a decrease in regional T(2) values. Specificity for the binding of the molecularly targeted anti-c-MET contrast agent was determined using rat hepatoma (H4-II-E-C3) cell cultures and immunofluorescence microscopic imaging of the targeting agents within neoplastic liver tissue 1 to 2 hours following intravenous administration of SPIO-anti-c-MET and MRI investigation. This method has the ability to visualize in vivo the overexpression of c-MET at early developmental stages of tumor formation.

  2. In Vivo Detection of c-MET Expression in a Rat Hepatocarcinogenesis Model Using Molecularly Targeted Magnetic Resonance Imaging

    Directory of Open Access Journals (Sweden)

    Rheal A. Towner

    2007-01-01

    Full Text Available The multifunctional growth factor scatter factor/hepatocyte growth factor and its tyrosine kinase receptor, c-MET, have been implicated in the genesis and malignant progression of numerous human malignancies, including hepatocellular carcinomas. The incidence of hepatocellular carcinomas in the United States has increased noticeably over the past two decades and is listed as the fifth major cancer in men worldwide. In this study, we used a choline-deficient l-amino acid (CDAA-defined rat hepatocarcinogenesis model to visualize increased in vivo expression of the c-MET antigen in neoplastic lesion formation with the use of a super paramagnetic iron oxide (SPIO–anti-c-MET molecularly targeted magnetic resonance imaging (MRI contrast agent. SPIO–anti-c-MET was used for the first time to detect overexpression of c-MET in neoplastic nodules and tumors within the livers of CDAA-treated rats, as determined by a decrease in MRI signal intensity and a decrease in regional T2 values. Specificity for the binding of the molecularly targeted anti-c-MET contrast agent was determined using rat hepatoma (H4-II-E-C3 cell cultures and immunofluorescence microscopic imaging of the targeting agents within neoplastic liver tissue 1 to 2 hours following intravenous administration of SPIO–anti-c-MET and MRI investigation. This method has the ability to visualize in vivo the overexpression of c-MET at early developmental stages of tumor formation.

  3. Detection of inflammatory bowel disease by proton magnetic resonance spectroscopy (1H MRS using an animal model

    Directory of Open Access Journals (Sweden)

    Dolenko Brion

    2007-11-01

    Full Text Available Abstract Background The aim of this study was to analyze the potential of proton magnetic resonance spectroscopy (1H MRS in diagnosing early inflammatory bowel disease (IBD. Methods Thirty male Sprague Dawley rats were fed 2% carrageenan in their diet for either 1 or 2 weeks. 1H MRS was performed ex-vivo on colonic mucosal samples (n = 123 and the spectra were analyzed by a multivariate method of analysis. The results of the multivariate analysis were correlated with histological analysis performed using H & E stain for the presence of inflammation in the samples from each group. Results Multivariate analysis classified the samples in their respective groups with an accuracy of 82%. Our region selection algorithm identified four regions in the spectra as being discriminatory. The metabolites assigned to these regions include creatine, phosphatidylcholine, the -CH2HC= group in fatty acyl chain, and the glycerol backbone of lipids. The differences in concentration of these metabolites in each group offer insight into the biochemical changes occurring during IBD and confer diagnostic potential to 1H MRS as a tool to study colonic inflammation in conjunction with biopsy. Conclusion 1H MRS is a sensitive tool to detect early colonic inflammation in an animal model of IBD.

  4. Simulation and modeling of whistler-mode wave growth through cyclotron resonance with energetic electrons in the magnetosphere

    International Nuclear Information System (INIS)

    Carlson, C.R.

    1987-01-01

    New models and simulations of wave growth experienced by electromagnetic waves propagating through the magnetosphere in the whistler mode are presented. For these waves, which have frequencies below the electron gyro and plasma frequencies, the magnetospheric plasma acts like a natural amplifier often amplifying the waves by ∼ 30 dB. The mechanism for growth is cyclotron resonance between the circularly polarized waves and the gyrating energetic electrons which make up the Van Allen radiation belts. The main emphasis is to simulate single-frequency wave pulses, in the 2-6 kHz range, that have been injected into the magnetosphere, near L ∼ 4, by the Stanford transmitting facility at Siple station, Antarctica. However, the results can also be applied to naturally occurring signals, signals from other transmitters, non-CW signals, and signals in other parts of the magnetosphere not probed by the Siple Station transmitter. Results show the importance of the transient aspects in the wave-growth process. The wave growth established as the wave propagates toward the equator, is given a spatially advancing wave phase structure by the geomagnetic inhomogeneity. Through the feedback of this radiation upon other electrons, conditions are set up that results in the linearly increasing output frequency with time

  5. Form factors in sinh- and sine-Gordon models, deformed Virasoro algebra, Macdonald polynomials and resonance identities

    International Nuclear Information System (INIS)

    Lashkevich, Michael; Pugai, Yaroslav

    2013-01-01

    We continue the study of form factors of descendant operators in the sinh- and sine-Gordon models in the framework of the algebraic construction proposed in [1]. We find the algebraic construction to be related to a particular limit of the tensor product of the deformed Virasoro algebra and a suitably chosen Heisenberg algebra. To analyze the space of local operators in the framework of the form factor formalism we introduce screening operators and construct singular and cosingular vectors in the Fock spaces related to the free field realization of the obtained algebra. We show that the singular vectors are expressed in terms of the degenerate Macdonald polynomials with rectangular partitions. We study the matrix elements that contain a singular vector in one chirality and a cosingular vector in the other chirality and find them to lead to the resonance identities already known in the conformal perturbation theory. Besides, we give a new derivation of the equation of motion in the sinh-Gordon theory, and a new representation for conserved currents

  6. Carotid wall volume quantification from magnetic resonance images using deformable model fitting and learning-based correction of systematic errors

    International Nuclear Information System (INIS)

    Hameeteman, K; Niessen, W J; Klein, S; Van 't Klooster, R; Selwaness, M; Van der Lugt, A; Witteman, J C M

    2013-01-01

    We present a method for carotid vessel wall volume quantification from magnetic resonance imaging (MRI). The method combines lumen and outer wall segmentation based on deformable model fitting with a learning-based segmentation correction step. After selecting two initialization points, the vessel wall volume in a region around the bifurcation is automatically determined. The method was trained on eight datasets (16 carotids) from a population-based study in the elderly for which one observer manually annotated both the lumen and outer wall. An evaluation was carried out on a separate set of 19 datasets (38 carotids) from the same study for which two observers made annotations. Wall volume and normalized wall index measurements resulting from the manual annotations were compared to the automatic measurements. Our experiments show that the automatic method performs comparably to the manual measurements. All image data and annotations used in this study together with the measurements are made available through the website http://ergocar.bigr.nl. (paper)

  7. Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging Data to Constrain a Positron Emission Tomography Kinetic Model: Theory and Simulations

    Directory of Open Access Journals (Sweden)

    Jacob U. Fluckiger

    2013-01-01

    Full Text Available We show how dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI data can constrain a compartmental model for analyzing dynamic positron emission tomography (PET data. We first develop the theory that enables the use of DCE-MRI data to separate whole tissue time activity curves (TACs available from dynamic PET data into individual TACs associated with the blood space, the extravascular-extracellular space (EES, and the extravascular-intracellular space (EIS. Then we simulate whole tissue TACs over a range of physiologically relevant kinetic parameter values and show that using appropriate DCE-MRI data can separate the PET TAC into the three components with accuracy that is noise dependent. The simulations show that accurate blood, EES, and EIS TACs can be obtained as evidenced by concordance correlation coefficients >0.9 between the true and estimated TACs. Additionally, provided that the estimated DCE-MRI parameters are within 10% of their true values, the errors in the PET kinetic parameters are within approximately 20% of their true values. The parameters returned by this approach may provide new information on the transport of a tracer in a variety of dynamic PET studies.

  8. Estimation of in vivo inter-vertebral loading during motion using fluoroscopic and magnetic resonance image informed finite element models.

    Science.gov (United States)

    Zanjani-Pour, Sahand; Meakin, Judith R; Breen, Alex; Breen, Alan

    2018-03-21

    Finite element (FE) models driven by medical image data can be used to estimate subject-specific spinal biomechanics. This study aimed to combine magnetic resonance (MR) imaging and quantitative fluoroscopy (QF) in subject-specific FE models of upright standing, flexion and extension. Supine MR images of the lumbar spine were acquired from healthy participants using a 0.5 T MR scanner. Nine 3D quasi-static linear FE models of L3 to L5 were created with an elastic nucleus and orthotropic annulus. QF data was acquired from the same participants who performed trunk flexion to 60° and trunk extension to 20°. The displacements and rotations of the vertebrae were calculated and applied to the FE model. Stresses were averaged across the nucleus region and transformed to the disc co-ordinate system (S1 = mediolateral, S2 = anteroposterior, S3 = axial). In upright standing S3 was predicted to be -0.7 ± 0.6 MPa (L3L4) and -0.6 ± 0.5 MPa (L4L5). S3 increased to -2.0 ± 1.3 MPa (L3L4) and -1.2 ± 0.6 MPa (L4L5) in full flexion and to -1.1 ± 0.8 MPa (L3L4) and -0.7 ± 0.5 MPa (L4L5) in full extension. S1 and S2 followed similar patterns; shear was small apart from S23. Disc stresses correlated to disc orientation and wedging. The results demonstrate that MR and QF data can be combined in a participant-specific FE model to investigate spinal biomechanics in vivo and that predicted stresses are within ranges reported in the literature. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Underwater noise from three types of offshore wind turbines: estimation of impact zones for harbor porpoises and harbor seals.

    Science.gov (United States)

    Tougaard, Jakob; Henriksen, Oluf Damsgaard; Miller, Lee A

    2009-06-01

    Underwater noise was recorded from three different types of wind turbines in Denmark and Sweden (Middelgrunden, Vindeby, and Bockstigen-Valar) during normal operation. Wind turbine noise was only measurable above ambient noise at frequencies below 500 Hz. Total sound pressure level was in the range 109-127 dB re 1 microPa rms, measured at distances between 14 and 20 m from the foundations. The 1/3-octave noise levels were compared with audiograms of harbor seals and harbor porpoises. Maximum 1/3-octave levels were in the range 106-126 dB re 1 microPa rms. Maximum range of audibility was estimated under two extreme assumptions on transmission loss (3 and 9 dB per doubling of distance, respectively). Audibility was low for harbor porpoises extending 20-70 m from the foundation, whereas audibility for harbor seals ranged from less than 100 m to several kilometers. Behavioral reactions of porpoises to the noise appear unlikely except if they are very close to the foundations. However, behavioral reactions from seals cannot be excluded up to distances of a few hundred meters. It is unlikely that the noise reaches dangerous levels at any distance from the turbines and the noise is considered incapable of masking acoustic communication by seals and porpoises.

  10. Numerical Simulation of Borehole Flow in Deep Monitor Wells, Pearl Harbor Aquifer, Oahu, Hawaii

    Science.gov (United States)

    Rotzoll, K.; Oki, D. S.; El-Kadi, A. I.

    2010-12-01

    Salinity profiles collected from uncased deep monitor wells are commonly used to monitor freshwater-lens thickness in coastal aquifers. However, vertical flow in these wells can cause the measured salinity to differ from salinity in the adjacent aquifer. Substantial borehole flow has been observed in uncased wells in the Pearl Harbor aquifer, Oahu, Hawaii. A numerical modeling approach, incorporating aquifer hydraulic characteristics and recharge rates representative of the Pearl Harbor aquifer, was used to evaluate the effects of borehole flow on measured salinity profiles from deep monitor wells. Borehole flow caused by vertical hydraulic gradients associated with the natural regional groundwater-flow system and local groundwater withdrawals was simulated. Model results were used to estimate differences between vertical salinity profiles in deep monitor wells and the adjacent aquifer in areas of downward, horizontal, and upward flow within the regional flow system—for cases with and without nearby pumped wells. Aquifer heterogeneity, represented in the model as layers of contrasting permeability, was incorporated in model scenarios. Results from this study provide insight into the magnitude of the differences between vertical salinity profiles from deep monitor wells and the salinity distributions in the aquifers. These insights are relevant and are critically needed for management and predictive modeling purposes.

  11. Self-consistent modeling of induced magnetic field in Titan's atmosphere accounting for the generation of Schumann resonance

    Science.gov (United States)

    Béghin, Christian

    2015-02-01

    This model is worked out in the frame of physical mechanisms proposed in previous studies accounting for the generation and the observation of an atypical Schumann Resonance (SR) during the descent of the Huygens Probe in the Titan's atmosphere on 14 January 2005. While Titan is staying inside the subsonic co-rotating magnetosphere of Saturn, a secondary magnetic field carrying an Extremely Low Frequency (ELF) modulation is shown to be generated through ion-acoustic instabilities of the Pedersen current sheets induced at the interface region between the impacting magnetospheric plasma and Titan's ionosphere. The stronger induced magnetic field components are focused within field-aligned arcs-like structures hanging down the current sheets, with minimum amplitude of about 0.3 nT throughout the ramside hemisphere from the ionopause down to the Moon surface, including the icy crust and its interface with a conductive water ocean. The deep penetration of the modulated magnetic field in the atmosphere is thought to be allowed thanks to the force balance between the average temporal variations of thermal and magnetic pressures within the field-aligned arcs. However, there is a first cause of diffusion of the ELF magnetic components, probably due to feeding one, or eventually several SR eigenmodes. A second leakage source is ascribed to a system of eddy-Foucault currents assumed to be induced through the buried water ocean. The amplitude spectrum distribution of the induced ELF magnetic field components inside the SR cavity is found fully consistent with the measurements of the Huygens wave-field strength. Waiting for expected future in-situ exploration of Titan's lower atmosphere and the surface, the Huygens data are the only experimental means available to date for constraining the proposed model.

  12. Spleen dynamic contrast-enhanced magnetic resonance imaging as a new method for staging liver fibrosis in a piglet model.

    Directory of Open Access Journals (Sweden)

    Li Zhou

    Full Text Available OBJECTIVE: To explore spleen hemodynamic alteration in liver fibrosis with dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI, and to determine how to stage liver fibrosis with spleen DCE-MRI parameters. MATERIALS AND METHODS: Sixteen piglets were prospectively used to model liver fibrosis staged by liver biopsy, and underwent spleen DCE-MRI on 0, 5th, 9th, 16th and 21st weekend after modeling this disease. DCE-MRI parameters including time to peak (TTP, positive enhancement integral (PEI, maximum slope of increase (MSI and maximum slope of decrease (MSD of spleen were measured, and statistically analyzed to stage this disease. RESULTS: Spearman's rank correlation tests showed that TTP tended to increase with increasing stages of liver fibrosis (r = 0.647, P0.05, and decreased from stage 2 to 4 (P0.05. Mann-Whitney tests demonstrated that TTP and PEI could classify fibrosis between stage 0 and 1-4, between 0-1 and 2-4, between 0-2 and 3-4, or between 0-3 and 4 (all P<0.01. MSD could discriminate between 0-2 and 3-4 (P = 0.006, or between 0-3 and 4 (P = 0.012. MSI could not differentiate between any two stages. Receiver operating characteristic analysis illustrated that area under receiver operating characteristic curve (AUC of TTP was larger than of PEI for classifying stage ≥1 and ≥2 (AUC = 0.851 and 0.783, respectively. PEI could best classify stage ≥3 and 4 (AUC = 0.903 and 0.96, respectively. CONCLUSION: Spleen DCE-MRI has potential to monitor spleen hemodynamic alteration and classify liver fibrosis stages.

  13. Piezoelectric MEMS resonators

    CERN Document Server

    Piazza, Gianluca

    2017-01-01

    This book introduces piezoelectric microelectromechanical (pMEMS) resonators to a broad audience by reviewing design techniques including use of finite element modeling, testing and qualification of resonators, and fabrication and large scale manufacturing techniques to help inspire future research and entrepreneurial activities in pMEMS. The authors discuss the most exciting developments in the area of materials and devices for the making of piezoelectric MEMS resonators, and offer direct examples of the technical challenges that need to be overcome in order to commercialize these types of devices. Some of the topics covered include: Widely-used piezoelectric materials, as well as materials in which there is emerging interest Principle of operation and design approaches for the making of flexural, contour-mode, thickness-mode, and shear-mode piezoelectric resonators, and examples of practical implementation of these devices Large scale manufacturing approaches, with a focus on the practical aspects associate...

  14. Resonant diphoton phenomenology simplified

    International Nuclear Information System (INIS)

    Panico, Giuliano; Vecchi, Luca; Wulzer, Andrea

    2016-01-01

    A framework is proposed to describe resonant diphoton phenomenology at hadron colliders in full generality. It can be employed for a comprehensive model-independent interpretation of the experimental data. Within the general framework, few benchmark scenarios are defined as representative of the various phenomenological options and/or of motivated new physics scenarios. Their usage is illustrated by performing a characterization of the 750 GeV excess, based on a recast of available experimental results. We also perform an assessment of which properties of the resonance could be inferred, after discovery, by a careful experimental study of the diphoton distributions. These include the spin J of the new particle and its dominant production mode. Partial information on its CP-parity can also be obtained, but only for J≥2. The complete determination of the resonance CP properties requires studying the pattern of the initial state radiation that accompanies the resonant diphoton production.

  15. Modeling and characterization of double resonant tunneling diodes for application as energy selective contacts in hot carrier solar cells

    Science.gov (United States)

    Jehl, Zacharie; Suchet, Daniel; Julian, Anatole; Bernard, Cyril; Miyashita, Naoya; Gibelli, Francois; Okada, Yoshitaka; Guillemolles, Jean-Francois

    2017-02-01

    Double resonant tunneling barriers are considered for an application as energy selective contacts in hot carrier solar cells. Experimental symmetric and asymmetric double resonant tunneling barriers are realized by molecular beam epitaxy and characterized by temperature dependent current-voltage measurements. The negative differential resistance signal is enhanced for asymmetric heterostructures, and remains unchanged between low- and room-temperatures. Within Tsu-Esaki description of the tunnel current, this observation can be explained by the voltage dependence of the tunnel transmission amplitude, which presents a resonance under finite bias for asymmetric structures. This effect is notably discussed with respect to series resistance. Different parameters related to the electronic transmission of the structure and the influence of these parameters on the current voltage characteristic are investigated, bringing insights on critical processes to optimize in double resonant tunneling barriers applied to hot carrier solar cells.

  16. Modeling the efficiency of Förster resonant energy transfer from energy relay dyes in dye-sensitized solar cells

    KAUST Repository

    Hoke, Eric T.; Hardin, Brian E.; McGehee, Michael D.

    2010-01-01

    Förster resonant energy transfer can improve the spectral breadth, absorption and energy conversion efficiency of dye sensitized solar cells. In this design, unattached relay dyes absorb the high energy photons and transfer the excitation

  17. Waves, Hydrodynamics and Sediment Transport Modeling at Grays Harbor, WA

    Science.gov (United States)

    2010-12-01

    advertising , publication, or promotional purposes. Citation of trade names does not constitute an official endorsement or approval of the use of such...mono- chromatic and irregular or random waves moving from deep to shallow waters over varying bathymetry (Nwogu and Demirbilek 2001; Demirbilek and

  18. Boussinesq Modeling for Inlets, Harbors & Structures (Bouss-2D)

    Science.gov (United States)

    2014-10-27

    circulation in surf and swash zone; wave-current interaction in channels and inlets; generation and impacts of infra-gravity waves on ports and...Guam, Samoa, Korea, Japan, Canada, EU countries, South Africa, Brazil, Peru, India, Indonesia , and Persian Gulf states. BMT helps the Corps evaluate

  19. Blood oxygen level dependent magnetic resonance imaging for detecting pathological patterns in lupus nephritis patients: a preliminary study using a decision tree model.

    Science.gov (United States)

    Shi, Huilan; Jia, Junya; Li, Dong; Wei, Li; Shang, Wenya; Zheng, Zhenfeng

    2018-02-09

    Precise renal histopathological diagnosis will guide therapy strategy in patients with lupus nephritis. Blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI) has been applicable noninvasive technique in renal disease. This current study was performed to explore whether BOLD MRI could contribute to diagnose renal pathological pattern. Adult patients with lupus nephritis renal pathological diagnosis were recruited for this study. Renal biopsy tissues were assessed based on the lupus nephritis ISN/RPS 2003 classification. The Blood oxygen level dependent magnetic resonance imaging (BOLD-MRI) was used to obtain functional magnetic resonance parameter, R2* values. Several functions of R2* values were calculated and used to construct algorithmic models for renal pathological patterns. In addition, the algorithmic models were compared as to their diagnostic capability. Both Histopathology and BOLD MRI were used to examine a total of twelve patients. Renal pathological patterns included five classes III (including 3 as class III + V) and seven classes IV (including 4 as class IV + V). Three algorithmic models, including decision tree, line discriminant, and logistic regression, were constructed to distinguish the renal pathological pattern of class III and class IV. The sensitivity of the decision tree model was better than that of the line discriminant model (71.87% vs 59.48%, P decision tree model was equivalent to that of the line discriminant model (63.87% vs 63.73%, P = 0.939) and higher than that of the logistic regression model (63.87% vs 38.0%, P decision tree model was greater than that of the line discriminant model (0.765 vs 0.629, P Decision tree models constructed using functions of R2* values may facilitate the prediction of renal pathological patterns.

  20. Computed Tomography Perfusion, Magnetic Resonance Imaging, and Histopathological Findings After Laparoscopic Renal Cryoablation: An In Vivo Pig Model

    DEFF Research Database (Denmark)

    Nielsen, Tommy Kjærgaard; Østraat, Øyvind; Graumann, Ole

    2017-01-01

    The present study investigates how computed tomography perfusion scans and magnetic resonance imaging correlates with the histopathological alterations in renal tissue after cryoablation. A total of 15 pigs were subjected to laparoscopic-assisted cryoablation on both kidneys. After intervention...... of follow-up, but on microscopic examination, the urothelium was found to be intact in all cases. In conclusion, cryoablation effectively destroyed renal parenchyma, leaving the urothelium intact. Both computed tomography perfusion and magnetic resonance imaging reflect the microscopic findings...