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Sample records for hantavirus infections sweden

  1. Hantavirus Infections

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    Camilo Guzmán T

    2017-05-01

    Full Text Available Hantaviruses are the causative agents of hantavirus pulmonary syndrome in humans in the Americas; The primary reservoirs are in the rodents of the subfamily Sigmodontinae. In South America, cases of hantavirus pulmonary syndrome caused by numerous viral genotypes have been diagnosed. In Colombia, different serological studies have reported the circulation of hantavirus in humans and rodents. These viruses act in an intimate association with a rodent species that serves as a reservoir and have a distribution around the wild rodent, being limited to a specific geographic region. In South America, the first HPS-associated hantavirus was described in 1993 in Brazil and was called Juquitiva and from 1993 to 2012, more than 1400 cases had been identified in Brazil. This syndrome should be suspected in all patients with respiratory distress syndrome of unclear etiology, in areas endemic for the disease, especially if accompanied by fever, marked leukocytosis and thrombocytopenia and bilateral interstitial infiltrates. Hemorrhagic febrile syndrome has not yet been described in the Americas. There are no clinical or laboratory signs that are pathognomonic of hantavirus infection. The treatment is based on adequate hydration, use of antipyretics and anti-inflammatories and patients with signs of severity should establish a more aggressive management. Triage is indispensable, patients with co-morbidities have a higher mortality risk and therefore should be hospitalized. Future research in Colombia should be directed to multidisciplinary studies that include viral isolation, different clinical forms of case presentation, epidemiological differences, risk factors, and taxonomy of viruses and rodents.

  2. Dobrava Hantavirus Infection Complicated by Panhypopituitarism, Istanbul, Turkey, 2010

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    Hofmann, Jörg; Canpolat, Alper Tunga; Türk, Ali; Ettinger, Jakob; Atmaca, Deniz; Akyar, Işın; Yücel, Serap; Arıkan, Ender; Uyar, Yavuz; Çağlayık, Dilek Y.; Kocagöz, Ayşe Sesin; Kaya, Ayşin; Kruger, Detlev H.

    2012-01-01

    We identified Dobrava-Belgrade virus infection in Turkey (from a strain related to hantavirus strains from nearby countries) in a patient who had severe symptoms leading to panhypopituitarism, but no known risk for hantavirus. Our findings emphasize the need for increased awareness of hantaviruses in the region and assessment of symptomatic persons without known risk factors for infection. PMID:22709722

  3. Hantaviral proteins: structure, functions and role in hantavirus infection

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    Musalwa eMuyangwa

    2015-11-01

    Full Text Available Hantaviruses are the members of the family Bunyaviridae that are naturally maintained in the populations of small mammals, mostly rodents. Most of these viruses can easily infect humans through contact with aerosols or dust generated by contaminated animal waste products. Depending on the particular hantavirus involved, human infection could result in either Hemorrhagic Fever with Renal Syndrome (HFRS or in Hantavirus Cardiopulmonary Syndrome (HCPS. In the past few years, clinical cases of the hantavirus caused diseases have been on the rise. Understanding structure of the hantavirus genome and the functions of the key viral proteins is critical for the therapeutic agents’ research. This paper gives a brief overview of the current knowledge on the structure and properties of the hantavirus nucleoprotein and the glycoproteins.

  4. Two Atypical Cases of Hantavirus Infections from Sri Lanka

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    N. D. B. Ehelepola

    2018-01-01

    Full Text Available There are two categories of hantaviruses resulting in two distinct illnesses. The Old World (Asia and Europe viruses give rise to hemorrhagic fever with renal syndrome (HFRS, and the New World (Americas viruses cause hantavirus pulmonary syndrome (HPS. Hantavirus infections have very similar clinical pictures and epidemiology to leptospirosis. Here, we present two cases of hantavirus infections from Sri Lanka (in South Asia initially misdiagnosed as leptospirosis and later further investigated and diagnosed as hantavirus infections with serological confirmation of the diagnosis. They had clinical pictures of a combination of both HFRS and HPS as well as the involvement of the central nervous system. Hantavirus infections are rarely diagnosed in South Asia. Reports on such atypical clinical pictures of hantavirus infections are extremely rare. Having arrived at the correct diagnosis late/retrospectively, both these patients recovered notwithstanding being seriously ill, indicating adequate supportive therapy can save lives in such cases. The emergence of the hantavirus, an infection seriously affecting multiple organ systems with a high case fatality rate that is spread by aerosol and other routes, could become a serious public health issue in Sri Lanka.

  5. Differential lymphocyte and antibody responses in deer mice infected with Sin Nombre hantavirus or Andes hantavirus.

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    Schountz, Tony; Quackenbush, Sandra; Rovnak, Joel; Haddock, Elaine; Black, William C; Feldmann, Heinz; Prescott, Joseph

    2014-08-01

    Hantavirus cardiopulmonary syndrome (HCPS) is a rodent-borne disease with a high case-fatality rate that is caused by several New World hantaviruses. Each pathogenic hantavirus is naturally hosted by a principal rodent species without conspicuous disease and infection is persistent, perhaps for life. Deer mice (Peromyscus maniculatus) are the natural reservoirs of Sin Nombre virus (SNV), the etiologic agent of most HCPS cases in North America. Deer mice remain infected despite a helper T cell response that leads to high-titer neutralizing antibodies. Deer mice are also susceptible to Andes hantavirus (ANDV), which causes most HCPS cases in South America; however, deer mice clear ANDV. We infected deer mice with SNV or ANDV to identify differences in host responses that might account for this differential outcome. SNV RNA levels were higher in the lungs but not different in the heart, spleen, or kidneys. Most ANDV-infected deer mice had seroconverted 14 days after inoculation, but none of the SNV-infected deer mice had. Examination of lymph node cell antigen recall responses identified elevated immune gene expression in deer mice infected with ANDV and suggested maturation toward a Th2 or T follicular helper phenotype in some ANDV-infected deer mice, including activation of the interleukin 4 (IL-4) pathway in T cells and B cells. These data suggest that the rate of maturation of the immune response is substantially higher and of greater magnitude during ANDV infection, and these differences may account for clearance of ANDV and persistence of SNV. Hantaviruses persistently infect their reservoir rodent hosts without pathology. It is unknown how these viruses evade sterilizing immune responses in the reservoirs. We have determined that infection of the deer mouse with its homologous hantavirus, Sin Nombre virus, results in low levels of immune gene expression in antigen-stimulated lymph node cells and a poor antibody response. However, infection of deer mice with a

  6. Evidence of human hantavirus infection and zoonotic investigation of hantavirus prevalence in rodents in western Java, Indonesia.

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    Kosasih, Herman; Ibrahim, Ima Nurisa; Wicaksana, Rudi; Alisjahbana, Bachti; Hoo, Yumilia; Yo, Iing H; Antonjaya, Ungke; Widjaja, Susana; Winoto, Imelda; Williams, Maya; Blair, Patrick J

    2011-06-01

    During febrile surveillance in the western Java City of Bandung, Indonesia, a patient with clinical symptoms consistent with hantavirus infection was found to have elevated titers of hantavirus-specific immunoglobulin M (IgM) and IgG antibodies. A subsequent epizoological investigation demonstrated a higher prevalence of hantavirus IgG antibodies in rodents trapped in the vicinity of the patient's home compared with rodents from a control area (13.2% vs. 4.7%, p = 0.036). The Old World Seoul hantavirus was detected by reverse transcriptase-polymerase chain reaction in the organs of 71% of the seropositive rodents tested. This is the first report of a Seoul virus infection in Indonesia supported by clinical, serological, and epizoological evidences. These findings suggest that hantavirus infection should be on the clinical differential diagnosis when acutely ill febrile patients report for care in western Java.

  7. Bessel collocation approach for approximate solutions of Hantavirus infection model

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    Suayip Yuzbasi

    2017-11-01

    Full Text Available In this study, a collocation method is introduced to find the approximate solutions of Hantavirus infection model which is a system of nonlinear ordinary differential equations. The method is based on the Bessel functions of the first kind, matrix operations and collocation points. This method converts Hantavirus infection model into a matrix equation in terms of the Bessel functions of first kind, matrix operations and collocation points. The matrix equation corresponds to a system of nonlinear equations with the unknown Bessel coefficients. The reliability and efficiency of the suggested scheme are demonstrated by numerical applications and all numerical calculations have been done by using a program written in Maple.

  8. Climate Variability and the Occurrence of Human Puumala Hantavirus Infections in Europe: A Systematic Review.

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    Roda Gracia, J; Schumann, B; Seidler, A

    2015-09-01

    Hantaviruses are distributed worldwide and are transmitted by rodents. In Europe, the infection usually manifests as a mild form of haemorrhagic fever with renal syndrome (HFRS) known as nephropathia epidemica (NE), which is triggered by the virus species Puumala. Its host is the bank vole (Myodes glareolus). In the context of climate change, interest in the role of climatic factors for the disease has increased. A systematic review was conducted to investigate the association between climate variability and the occurrence of human Puumala hantavirus infections in Europe. We performed a literature search in the databases MEDLINE, EMBASE and Web of Science. Studies that investigated Puumala virus infection and climatic factors in any European country with a minimum collection period of 2 years were included. The selection of abstracts and the evaluation of included studies were performed by two independent reviewers. A total of 434 titles were identified in the databases, of which nine studies fulfilled the inclusion criteria. The majority of studies were conducted in central Europe (Belgium, France and Germany), while only two came from the north (Sweden) and one from the south (Bosnia). Strong evidence was found for a positive association between temperature and NE incidence in central Europe, while the evidence for northern Europe so far appears insufficient. Results regarding precipitation were contradictory. Overall, the complex relationships between climate and hantavirus infections need further exploration to identify specific health risks and initiate appropriate intervention measures in the context of climate change. © 2014 Blackwell Verlag GmbH.

  9. Serological evidence of hantavirus infection in rural and urban regions in the state of Amazonas, Brazil

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    João Bosco Lima Gimaque

    2012-02-01

    Full Text Available Hantavirus disease is caused by the hantavirus, which is an RNA virus belonging to the family Bunyaviridae. Hantavirus disease is an anthropozoonotic infection transmitted through the inhalation of aerosols from the excreta of hantavirus-infected rodents. In the county of Itacoatiara in the state of Amazonas (AM, Brazil, the first human cases of hantavirus pulmonary and cardiovascular syndrome were described in July 2004. These first cases were followed by two fatal cases, one in the municipality of Maués in 2005 and another in Itacoatiara in 2007. In this study, we investigated the antibody levels to hantavirus in a population of 1,731 individuals from four different counties of AM. Sera were tested by IgG/IgM- enzyme-linked immune-sorbent assay using a recombinant nucleocapsid protein of the Araraquara hantavirus as an antigen. Ten sera were IgG positive to hantavirus (0.6%. Among the positive sera, 0.8% (1/122, 0.4% (1/256, 0.2% (1/556 and 0.9% (7/797 were from Atalaia do Norte, Careiro Castanho, Itacoatiara and Lábrea, respectively. None of the sera in this survey were IgM-positive. Because these counties are distributed in different areas of AM, we can assume that infected individuals are found throughout the entire state, which suggests that hantavirus disease could be a local emerging health problem.

  10. Climate change and sugarcane expansion increase Hantavirus infection risk.

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    Prist, Paula Ribeiro; Uriarte, María; Fernandes, Katia; Metzger, Jean Paul

    2017-07-01

    Hantavirus Cardiopulmonary Syndrome (HCPS) is a disease caused by Hantavirus, which is highly virulent for humans. High temperatures and conversion of native vegetation to agriculture, particularly sugarcane cultivation can alter abundance of rodent generalist species that serve as the principal reservoir host for HCPS, but our understanding of the compound effects of land use and climate on HCPS incidence remains limited, particularly in tropical regions. Here we rely on a Bayesian model to fill this research gap and to predict the effects of sugarcane expansion and expected changes in temperature on Hantavirus infection risk in the state of São Paulo, Brazil. The sugarcane expansion scenario was based on historical data between 2000 and 2010 combined with an agro-environment zoning guideline for the sugar and ethanol industry. Future evolution of temperature anomalies was derived using 32 general circulation models from scenarios RCP4.5 and RCP8.5 (Representative greenhouse gases Concentration Pathways adopted by IPCC). Currently, the state of São Paulo has an average Hantavirus risk of 1.3%, with 6% of the 645 municipalities of the state being classified as high risk (HCPS risk ≥ 5%). Our results indicate that sugarcane expansion alone will increase average HCPS risk to 1.5%, placing 20% more people at HCPS risk. Temperature anomalies alone increase HCPS risk even more (1.6% for RCP4.5 and 1.7%, for RCP8.5), and place 31% and 34% more people at risk. Combined sugarcane and temperature increases led to the same predictions as scenarios that only included temperature. Our results demonstrate that climate change effects are likely to be more severe than those from sugarcane expansion. Forecasting disease is critical for the timely and efficient planning of operational control programs that can address the expected effects of sugarcane expansion and climate change on HCPS infection risk. The predicted spatial location of HCPS infection risks obtained here can be

  11. Climate change and sugarcane expansion increase Hantavirus infection risk.

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    Paula Ribeiro Prist

    2017-07-01

    Full Text Available Hantavirus Cardiopulmonary Syndrome (HCPS is a disease caused by Hantavirus, which is highly virulent for humans. High temperatures and conversion of native vegetation to agriculture, particularly sugarcane cultivation can alter abundance of rodent generalist species that serve as the principal reservoir host for HCPS, but our understanding of the compound effects of land use and climate on HCPS incidence remains limited, particularly in tropical regions. Here we rely on a Bayesian model to fill this research gap and to predict the effects of sugarcane expansion and expected changes in temperature on Hantavirus infection risk in the state of São Paulo, Brazil. The sugarcane expansion scenario was based on historical data between 2000 and 2010 combined with an agro-environment zoning guideline for the sugar and ethanol industry. Future evolution of temperature anomalies was derived using 32 general circulation models from scenarios RCP4.5 and RCP8.5 (Representative greenhouse gases Concentration Pathways adopted by IPCC. Currently, the state of São Paulo has an average Hantavirus risk of 1.3%, with 6% of the 645 municipalities of the state being classified as high risk (HCPS risk ≥ 5%. Our results indicate that sugarcane expansion alone will increase average HCPS risk to 1.5%, placing 20% more people at HCPS risk. Temperature anomalies alone increase HCPS risk even more (1.6% for RCP4.5 and 1.7%, for RCP8.5, and place 31% and 34% more people at risk. Combined sugarcane and temperature increases led to the same predictions as scenarios that only included temperature. Our results demonstrate that climate change effects are likely to be more severe than those from sugarcane expansion. Forecasting disease is critical for the timely and efficient planning of operational control programs that can address the expected effects of sugarcane expansion and climate change on HCPS infection risk. The predicted spatial location of HCPS infection risks

  12. Multiple Co-infections of Rodents with Hantaviruses, Leptospira, and Babesia in Croatia

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    Turk, Nenad; Korva, Miša; Margaletić, Josip; Beck, Relja; Vucelja, Marko; Habuš, Josipa; Svoboda, Petra; Županc, Tatjana Avšič; Henttonen, Heikki; Markotić, Alemka

    2012-01-01

    Abstract Hantaviruses, Leptospira spp., and Babesia spp. are rodent-borne pathogens present worldwide. We studied multiple co-infections of small rodents in Croatia with all three pathogens. Twenty-eight Apodemus flavicollis and 16 Myodes glareolus were tested for the presence of hantavirus RNA by real-time RT-PCR, Leptospira strains by renoculture method and Babesia DNA by PCR. Anti-hantavirus antibodies and anti-Leptospira antibodies were detected by serological methods. Very high infection rates with each pathogen were found in A. flavicollis: 20 of 28 rodents (71%) were infected with Dobrava virus, 13 rodents (46%) were infected with Leptospira, and 5 rodents (18%) were infected with Babesia. Multiple co-infections with all three pathogens were found in 3 of 28 (11%) A. flavicollis animals, suggesting that the same rodent host can be infected with several pathogens at the same time. Dual infections with both hantaviruses and Leptospira were found in 7 of 44 rodents (16%), with hantaviruses and Babesia in 2 rodents (5%), and double infection with both Leptospira and Babesia were found in 1 rodent (2%). Since hantaviruses, Leptospira, and Babesia have similar geographical distributions, it is to be expected that in other parts of the world multiple co-infections, representing a serious threat to public health, can be found. PMID:22217170

  13. [Increase of Hantavirus infections in France, 2003].

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    Mailles, A; Vaillant, V; Haeghebaert, S; Fradet, M R; Capek, I; Zeller, H

    2005-02-01

    Hantaviral infections causing hemorrhagic fever with renal syndrome are endemic in North Eastern France. Humans are contaminated by the inhalation of aerosols contaminated by rodent faeces. In February 2003, the National reference centre (NRC) for hemorrhagic fevers detected an increased number of cases. An investigation was carried out to confirm the outbreak and take appropriate control measures. Cases were collected by the NRC. A case was defined as a person living in France with symptoms compatible with hantaviral infection and a positive blood test both for specific Puumala IgM, and IgG. Clinical information and at-risk exposures during the 2 weeks before onset were recorded. In 2003, 128 cases were diagnosed (61 in 2002). The median age of patients was 38, 77% were men and 82% were hospitalized. Patients were living in North-Eastern France. Clusters were detected in the Ardennes and Oise districts. Occupation (35%) (in agriculture, forestry, and construction work), manipulation of firewood (35%), gardening (29%), and outdoors leisure (14%) were identified as at-risk exposures in these cases. An increased number of positive diagnoses of hantaviral infections was confirmed. The location and at-risk exposures of the cases were identical in previous investigations. Exclusion and prevention of rodents' access to houses and avoiding the inhalation of contaminated dust are the only possible prevention measures of hantaviral infections. Information about the disease and its prevention needs to be made widely available to both healthcare professionals and the general population living in endemic areas.

  14. Tula hantavirus NSs protein accumulates in the perinuclear area in infected and transfected cells.

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    Virtanen, Jussi Oskari; Jääskeläinen, Kirsi Maria; Djupsjöbacka, Janica; Vaheri, Antti; Plyusnin, Alexander

    2010-01-01

    The small RNA segment of some hantaviruses (family Bunyaviridae) encodes two proteins: the nucleocapsid protein and, in an overlapping reading frame, a non-structural (NSs) protein. The hantavirus NSs protein, like those of orthobunya- and phleboviruses, counteracts host innate immunity. Here, for the first time, the NSs protein of a hantavirus (Tula virus) has been observed in infected cells and shown to localize in the perinuclear area. Transiently expressed NSs protein showed similar localization, although the kinetics was slightly different, suggesting that to reach its proper location in the infected cell, the NSs protein does not have to cooperate with other viral proteins.

  15. Detection of Puumala hantavirus antigen in human intestine during acute hantavirus infection.

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    Joerg Latus

    Full Text Available BACKGROUND: Puumala virus (PUUV is the most important hantavirus species in Central Europe. Nephropathia epidemica (NE, caused by PUUV, is characterized by acute renal injury (AKI with thrombocytopenia and frequently gastrointestinal symptoms. METHODS: 456 patients with serologically and clinically confirmed NE were investigated at time of follow-up in a single clinic. The course of the NE was investigated using medical reports. We identified patients who had endoscopy with intestinal biopsy during acute phase of NE. Histopathological, immunohistochemical and molecular analyses of the biopsies were performed. RESULTS: Thirteen patients underwent colonoscopy or gastroscopy for abdominal pain, diarrhea, nausea and vomiting during acute phase of NE. Immunohistochemistry (IHC revealed PUUV nucleocapsid antigen in 11 biopsies from 8 patients; 14 biopsies from 5 patients were negative for PUUV nucleocapsid antigen. IHC localized PUUV nucleocapsid antigen in endothelial cells of capillaries or larger vessels in the lamina propria. Rate of AKI was not higher and severity of AKI was not different in the PUUV-positive compared to the PUUV-negative group. All IHC positive biopsies were positive for PUUV RNA using RT-PCR. Phylogenetic reconstruction revealed clustering of all PUUV strains from this study with viruses previously detected from the South-West of Germany. Long-term outcome was favorable in both groups. CONCLUSIONS: In patients with NE, PUUV nucleocapsid antigen and PUUV RNA was detected frequently in the intestine. This finding could explain frequent GI-symptoms in NE patients, thus demonstration of a more generalized PUUV infection. The RT-PCR was an effective and sensitive method to detect PUUV RNA in FFPE tissues. Therefore, it can be used as a diagnostic and phylogenetic approach also for archival materials. AKI was not more often present in patients with PUUV-positive IHC. This last finding should be investigated in larger numbers of

  16. Development of a novel plaque reduction neutralisation test for hantavirus infection

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    Michelly de Pádua

    2015-08-01

    Full Text Available In the Americas, hantaviruses cause severe cardiopulmonary syndrome (HCPS with a high fatality rate. Hantavirus infection is commonly diagnosed using serologic techniques and reverse transcription-polymerase chain reaction. This paper presents a novel plaque reduction neutralisation test (PRNT for detecting antibodies to Brazilian hantavirus. Using PRNT, plaque detection was enhanced by adding 0.6% of dimethyl sulfoxide into the overlay culture medium of the infected cells. This procedure facilitated clear visualisation of small plaques under the microscope and provided for easy and accurate plaque counting. The sera from 37 HCPS patients from the city of Ribeirão Preto, Brazil was evaluated for the Rio Mamoré virus (RIOMV using PRNT. Six samples exhibited neutralising antibodies; these antibodies exhibited a low titre. The low level of seropositive samples may be due to fewer cross-reactions between two different hantavirus species; the patients were likely infected by Araraquara virus (a virus that has not been isolated and RIOMV was used for the test. This assay offers a new approach to evaluating and measuring neutralising antibodies produced during hantavirus infections and it can be adapted to other hantaviruses, including viruses that will be isolated in the future.

  17. Study of hantavirus infection in captive breed colonies of wild rodents

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    RC Oliveira

    2004-10-01

    Full Text Available Wild sigmondontine rodents are known to be the reservoir of several serotypes of New World hantaviruses. The mechanism of viral transmission is by aerosol inhalation of the excreta from infected rodents. Considering that the captive breed colonies of various wild mammals may present a potencial risk for hantaviral transmission, we examined 85 speciemens of Thrichomys spp. (Echimyidae and 17 speciemens of Nectomys squamipes (Sigmodontinae from our colony for the presence of hantavirus infections. Blood samples were assayed for the presence of antibodies to Andes nucleocapsid antigen using enzyme-linked immunosorbent assay (ELISA. Additionally, serum samples from workers previously exposed to wild rodents, in the laboratories where the study was conducted, were also tested by ELISA to investigate prevalence of anti-hantavirus IgG antibodies. All blood samples were negative for hantavirus antibodies. Although these results suggest that those rodent's colonies are hantavirus free, the work emphasizes the need for hantavirus serological monitoring in wild colonized rodents and secure handling potentially infected rodents as important biosafety measures.

  18. First serologic evidence of human hantavirus infection in Alagoas State in Northeastern Brazil

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    José Alfredo dos Santos-Júnior

    Full Text Available Abstract INTRODUCTION: Hantavirus cardiopulmonary syndrome (HCPS is rare in Northeastern Brazil. METHODS: Prospective surveillance was conducted over a two-year period in Alagoas State, Northeastern Brazil. The prevalence of anti-hantavirus N-antigen IgM and IgG in human serum samples was determined by enzyme-linked immunosorbent assay testing. RESULTS: High avidity IgG was found in nine of 476 serum samples tested (from 102 patients with clinical manifestations compatible with HCPS, 124 patients with leptospirosis, and 250 healthy rural workers. CONCLUSIONS: Serologic evidence of past hantavirus infection in residents of Alagoas State indicates that hantaviruses are present in northeastern Brazil, even in areas silent for HCPS.

  19. Two cases of Hantavirus infection in Crimean-Congo Haemorrhagic Fever endemic region

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    Mustafa Sünbül

    2012-09-01

    Full Text Available Crimean-Congo Hemorrhagic Fever (CCHF and Leptospirosis are endemic in our region. Hantavirus infections may beconfused with similar clinical picture zoonotic infections. Two patients with fever, malaise, cough, phlegm, nausea, vomiting,thrombocytopenia, renal failure, elevated transaminases, and a history of mouse contact were hospitalized in ourclinic with a presumptive diagnosis of leptospirosis, pneumonia, CCHF and Hantavirus infections. Empirical antibiotictreatment was initiated and CCHF and leptospirosis was ruled out with laboratory tests. Hantavirus immunoglobulin(Ig-G and Ig-M antibodies were detected positive by immunofluorescent antibody (IFA method in both cases but,Dobrova virus was detected in only one patient with immunoblotting methods. Both patients were discharged aftertreatment. Hantavirus infections may be misdiagnosed as zoonotic infections since they have similar clinical picture. Itshould be considered in the differential diagnosis of patients with a history of contact with mouse. J Microbiol Infect Dis2012; 2(3: 117-120Key words: Hantavirus, hemorrhagic fever, renal syndrome, pulmonary syndrome

  20. Autoimmune polyendocrinopathy and hypophysitis after Puumala hantavirus infection

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    Marlene Tarvainen

    2016-11-01

    Full Text Available Puumala hantavirus (PUUV infection causes nephropathia epidemica (NE, a relatively mild form of haemorrhagic fever with renal syndrome (HFRS. Hypophyseal haemorrhage and hypopituitarism have been described in case reports on patients with acute NE. Chronic hypopituitarism diagnosed months or years after the acute illness has also been reported, without any signs of a haemorrhagic aetiology. The mechanisms leading to the late-onset hormonal defects remain unknown. Here, we present a case of NE-associated autoimmune polyendocrinopathy and hypopituitarism presumably due to autoimmune hypophysitis. Thyroid peroxidase antibody seroconversion occurred between 6 and 12 months, and ovarian as well as glutamate decarboxylase antibodies were found 18 months after acute NE. Brain MRI revealed an atrophic adenohypophysis with a heterogeneous, low signal intensity compatible with a sequela of hypophysitis. The patient developed central (or mixed central and peripheral hypothyroidism, hypogonadism and diabetes insipidus, all requiring hormonal replacement therapy. This case report suggests that late-onset hormonal defects after PUUV infection may develop by an autoimmune mechanism. This hypothesis needs to be confirmed by prospective studies with sufficient numbers of patients.

  1. Epidemiology and laboratory diagnosis of hantavirus (HTV) infections.

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    Clement, J; McKenna, P; Groen, J; Osterhaus, A; Colson, P; Vervoort, T; van der Groen, G; Lee, H W

    1995-01-01

    Hantavirus (HTV) is recently discovered "hemorrhagic fever virus" belonging to the Bunyaviridae family, which is spread throughout the world by wild rodents and/or laboratory rats. During an epidemic in the Belgian-French Ardennes in 1993, more than 200 acute cases were recorded of the milder European form of HTV-illness, otherwise known as Nephropathia epidemica (NE). This variant may be recognized by the sudden onset of fever, acute renal failure, thrombocytopenia and sometimes by ophthalmologic complications. The symptomatology is rather aspecific and diagnosis can only be confirmed by serologic tests, of which the best option nowadays seems to be: screening by IgG EIA, followed by IgM confirmation with a mu-capture EIA test. Some of the tests described allow an evaluation of the causative serotype or even the moment of infection. Next to the "classic" serologic assays for detection of specific viral antibodies, we describe briefly our own experience with newer tests such as "high density particle agglutination" and "line immuno assay". Polymerase chain reaction for viral RNA genome typing and immunohistochemical colouring of the viral antigen in tissues seem to offer promising alternatives for the immediate future.

  2. Epidemiology and laboratory diagnosis of Hantavirus (HTV) infections.

    NARCIS (Netherlands)

    J.P.G. Clement; P. McKenna; J. Groen (Jan); A.D.M.E. Osterhaus (Albert); P. Colson; T. Vervoort; G. van der Groen (Guido); H.W. Lee

    1995-01-01

    textabstractHantavirus (HTV) is recently discovered "hemorrhagic fever virus" belonging to the Bunyaviridae family, which is spread throughout the world by wild rodents and/or laboratory rats. During an epidemic in the Belgian-French Ardennes in 1993, more than 200 acute cases were recorded of the

  3. Puumala hantavirus infection in humans and in the reservoir host, Ardennes region, France.

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    Sauvage, F; Penalba, C; Vuillaume, P; Boue, F; Coudrier, D; Pontier, D; Artois, M

    2002-12-01

    We compared the occurrence of nephropathia epidemica cases, over a multi-annual population cycle, in northeastern France with the hantavirus serology for bank voles captured in the same area. We discuss hypotheses to explain the pattern of infection in both humans and rodents and their synchrony.

  4. [The role of natural environment in spreading of hantavirus--model of the correlation between host, pathogen and human infections].

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    Baumann, Anna; Dudek, Dorota; Sadkowska-Todys, Małgorzata

    2007-01-01

    The environmental changes caused by humans influence ecosystem and thus have significant impact on occurrence of emerging and re-emerging diseases. The hantavirus infection belong to the one of them. The aim of this paper was to present current knowledge about relationship between hantavirus, their natural host and the spread of the infection to people. Rodents constitute both the natural host of the hantaviruses and the reservoir of hantavirus for environment. Circulation of the virus in the rodent population is crucial to maintain the virus in the environment. The individual characteristics of rodents influence on risk of infection with hantavirus. However, this relationship is still unexplained. Risk of pathogen exposure often increases with age and behavioral differences associated with the sex of the susceptible individual. Mating behaviors seem to play an important role in the spread of the virus among rodents. Human incidence of hantavirus infection has in general been found to correlate to the population size of rodent host especially in the model of nephropathia epidemica (NE; a mild form of HFRS), Puumala virus (PUU) and bank voles. The occurrence of hantavirus infections in humans is assumed to rise as a secondary effect from altered population sizes of rodents in a changing environment due to e.g. mast years, forest fragmentation, global warming.

  5. Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system.

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    Shannon L Taylor

    Full Text Available Hemorrhagic fever with renal syndrome (HFRS and hantavirus pulmonary syndrome (HPS are diseases caused by hantavirus infections and are characterized by vascular leakage due to alterations of the endothelial barrier. Hantavirus-infected endothelial cells (EC display no overt cytopathology; consequently, pathogenesis models have focused either on the influx of immune cells and release of cytokines or on increased degradation of the adherens junction protein, vascular endothelial (VE-cadherin, due to hantavirus-mediated hypersensitization of EC to vascular endothelial growth factor (VEGF. To examine endothelial leakage in a relevant in vitro system, we co-cultured endothelial and vascular smooth muscle cells (vSMC to generate capillary blood vessel-like structures. In contrast to results obtained in monolayers of cultured EC, we found that despite viral replication in both cell types as well as the presence of VEGF, infected in vitro vessels neither lost integrity nor displayed evidence of VE-cadherin degradation. Here, we present evidence for a novel mechanism of hantavirus-induced vascular leakage involving activation of the plasma kallikrein-kinin system (KKS. We show that incubation of factor XII (FXII, prekallikrein (PK, and high molecular weight kininogen (HK plasma proteins with hantavirus-infected EC results in increased cleavage of HK, higher enzymatic activities of FXIIa/kallikrein (KAL and increased liberation of bradykinin (BK. Measuring cell permeability in real-time using electric cell-substrate impedance sensing (ECIS, we identified dramatic increases in endothelial cell permeability after KKS activation and liberation of BK. Furthermore, the alterations in permeability could be prevented using inhibitors that directly block BK binding, the activity of FXIIa, or the activity of KAL. Lastly, FXII binding and autoactivation is increased on the surface of hantavirus-infected EC. These data are the first to demonstrate KKS activation

  6. Hantaviruses in Africa.

    Science.gov (United States)

    Witkowski, Peter T; Klempa, Boris; Ithete, Ndapewa L; Auste, Brita; Mfune, John K E; Hoveka, Julia; Matthee, Sonja; Preiser, Wolfgang; Kruger, Detlev H

    2014-07-17

    This paper summarizes the progress in the search for hantaviruses and hantavirus infections in Africa. After having collected molecular evidence of an indigenous African hantavirus in 2006, an intensive investigation for new hantaviruses has been started in small mammals. Various novel hantaviruses have been molecularly identified not only in rodents but also in shrews and bats. In addition, the first African hantavirus, Sangassou virus, has been isolated and functionally characterized in cell culture. Less is known about the ability of these hantaviruses to infect humans and to cause diseases. To date, no hantavirus genetic material could be amplified from patients' specimens collected in Africa. Serological studies in West Africa, based on a battery of screening and confirmatory assays, led to the detection of hantavirus antibodies in the human population and in patients with putative hantavirus disease. In addition to this overview, we present original data from seroepidemiological and field studies conducted in the Southern part of Africa. A human seroprevalence rate of 1.0% (n=1442) was detected in the South African Cape Region whereas no molecular evidence for the presence of hantavirus was found in 2500 small animals trapped in South Africa and Namibia. Copyright © 2014 Elsevier B.V. All rights reserved.

  7. Epidemiology of Hantavirus Infections in the United States

    Science.gov (United States)

    1991-06-08

    Hantaviruses (Family Bunyaviridae) are the etiological agents responsible for a spectrum of illnesses referred to collectively as hemorrhagic fever with...seropositives without chronic disease, one was admitted for severe preeclampsia , one for a psychiatric disorder, and three for complications from their...there was a marked difference between seropositives and seronegatives in the presumed etiology of renal disease (Table 7, Appendix 2). Seropositives had

  8. Hantaviruses as emergent zoonoses

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    LS Ullmann

    2008-01-01

    Full Text Available Hantaviruses belong to the Bunyaviridae family, which consists of vector-borne viruses. These viruses can provoke two infection types: hemorrhagic fever with renal syndrome (HFRS - which occurs in the Old World - and hantavirus cardiopulmonary syndrome (HCPS - an emergent zoonosis that can be found in many countries of the western hemisphere. Rodents are hantavirus reservoirs and each species seems to host a different virus type. Humans acquire the infection by inhaling contaminated aerosol particles eliminated by infected animals. The factors involved in the emergence of hantavirus infections in the human population include ecological modifications and changes in human activities. The most important risk factor is contact between man and rodents, as a result of agricultural, forestry or military activities. Rodent control remains the primary strategy for preventing hantavirus diseases, including via health education and hygienic habits.

  9. A rapid method for infectivity titration of Andes hantavirus using flow cytometry.

    Science.gov (United States)

    Barriga, Gonzalo P; Martínez-Valdebenito, Constanza; Galeno, Héctor; Ferrés, Marcela; Lozach, Pierre-Yves; Tischler, Nicole D

    2013-11-01

    The focus assay is currently the most commonly used technique for hantavirus titer determination. This method requires an incubation time of between 5 and 11 days to allow the appearance of foci after several rounds of viral infection. The following work presents a rapid Andes virus (ANDV) titration assay, based on viral nucleocapsid protein (N) detection in infected cells by flow cytometry. To this end, an anti-N monoclonal antibody was used that was developed and characterized previously. ANDV N could be detected as early as 6 h post-infection, while viral release was not observed until 24-48 h post-infection. Given that ANDV detection was performed during its first round of infection, a time reduction for titer determination was possible and provided results in only two days. The viral titer was calculated from the percentage of N positive cells and agreed with focus assay titers. Furthermore, the assay was applied to quantify the inhibition of ANDV cell entry by patient sera and by preventing endosome acidification. This novel hantavirus titration assay is a highly quantitative and sensitive tool that facilitates infectivity titration of virus stocks, rapid screening for antiviral drugs, and may be further used to detect and quantify infectious virus in human samples. Copyright © 2013 Elsevier B.V. All rights reserved.

  10. Using Geographic Information System-based Ecologic Niche Models to Forecast the Risk of Hantavirus Infection in Shandong Province, China

    Science.gov (United States)

    Wei, Lan; Qian, Quan; Wang, Zhi-Qiang; Glass, Gregory E.; Song, Shao-Xia; Zhang, Wen-Yi; Li, Xiu-Jun; Yang, Hong; Wang, Xian-Jun; Fang, Li-Qun; Cao, Wu-Chun

    2011-01-01

    Hemorrhagic fever with renal syndrome (HFRS) is an important public health problem in Shandong Province, China. In this study, we combined ecologic niche modeling with geographic information systems (GIS) and remote sensing techniques to identify the risk factors and affected areas of hantavirus infections in rodent hosts. Land cover and elevation were found to be closely associated with the presence of hantavirus-infected rodent hosts. The averaged area under the receiver operating characteristic curve was 0.864, implying good performance. The predicted risk maps based on the model were validated both by the hantavirus-infected rodents' distribution and HFRS human case localities with a good fit. These findings have the applications for targeting control and prevention efforts. PMID:21363991

  11. Serological Evidence of Hantavirus Infection in Apparently Healthy People from Rural and Slum Communities in Southern Chile

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    Claudia Muñoz-Zanzi

    2015-04-01

    Full Text Available Hantavirus disease in America has been recognizable because of its rapid progression in clinical cases, occurrence in previously healthy young adults, and high case fatality rate. Hantavirus disease has been proposed now to define the diversity of clinical manifestations. Since 1995, a total of 902 cases of hantavirus pulmonary syndrome have been reported in Chile, caused by Andes virus (ANDV, with overall fatality of 32%. This report describes the sero-epidemiology of hantavirus in apparently healthy people in rural and urban slum communities from southern Chile. Ten of 934 samples yielded a positive result resulting in a seroprevalence of 1.07% (95% confidence intervals: 0.05%–2.0%. A higher proportion of positive samples was found among individuals from rural villages (1.3% and slums (1.5% compared with farms (0.5%. Seropositivity was associated with age (p = 0.011, low education level (p = 0.006 and occupations linked to the household (homemaker, retired, or student (p = 0.016. No evidence of infection was found in 38 sigmodontinae rodents trapped in the peri-domestic environment. Our findings highlight that exposure risk was associated with less documented risk factors, such as women in slum and rural villages, and the occurrence of infection that may have presented as flu-like illness that did not require medical attention or was misdiagnosed.

  12. Rodent Abundance and Hantavirus Infection in Protected Area, East-Central Argentina

    Science.gov (United States)

    Maroli, Malena; Vadell, María Victoria; Padula, Paula

    2018-01-01

    We captured 3 hantavirus rodent hosts in Otamendi Natural Reserve, Argentina, during 2007–2012. Hantavirus antibodies were found only in Akodon azarae grass mice, mainly in males and old animals. Higher abundance of this species was associated with warm and rainy weather and high water levels, which peaked after a strong El Niño event. PMID:29260665

  13. Serological evidence of hantavirus infection in an urban area in Mato Grosso State, Brazil

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    Carla Julia da Silva Pessoa Vieira

    2016-06-01

    Full Text Available Abstract: INTRODUCTION: In Brazil, Mato Grosso (MT has the highest number of hantavirus cardiopulmonary syndrome cases. Our study aimed to identify anti-hantavirus antibodies in the sera of patients from Sinop, MT, presenting with acute febrile illness. METHODS: A retrospective analysis of data for 198 sera samples assessed using enzyme-linked immunosorbent assay (ELISA was conducted. RESULTS: Immunoglobulins G (IgGs against the hantavirus nucleoprotein were found in 13.6% of the tested sera. No sample had immunoglobulin M (IgM antibodies to hantavirus. Seropositivity occurred mainly in female residents in urban areas who worked around the household. CONCLUSIONS: Our findings suggest circulation of hantavirus in Sinop.

  14. Puumala hantavirus infections in bank vole populations: host and virus dynamics in Central Europe.

    Science.gov (United States)

    Reil, Daniela; Rosenfeld, Ulrike M; Imholt, Christian; Schmidt, Sabrina; Ulrich, Rainer G; Eccard, Jana A; Jacob, Jens

    2017-02-28

    In Europe, bank voles (Myodes glareolus) are widely distributed and can transmit Puumala virus (PUUV) to humans, which causes a mild to moderate form of haemorrhagic fever with renal syndrome, called nephropathia epidemica. Uncovering the link between host and virus dynamics can help to prevent human PUUV infections in the future. Bank voles were live trapped three times a year in 2010-2013 in three woodland plots in each of four regions in Germany. Bank vole population density was estimated and blood samples collected to detect PUUV specific antibodies. We demonstrated that fluctuation of PUUV seroprevalence is dependent not only on multi-annual but also on seasonal dynamics of rodent host abundance. Moreover, PUUV infection might affect host fitness, because seropositive individuals survived better from spring to summer than uninfected bank voles. Individual space use was independent of PUUV infections. Our study provides robust estimations of relevant patterns and processes of the dynamics of PUUV and its rodent host in Central Europe, which are highly important for the future development of predictive models for human hantavirus infection risk.

  15. A retrospective serologic survey of hantavirus infections in the county of Cássia dos Coqueiros, State of São Paulo, Brazil

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    Soraya Jabur Badra

    2012-08-01

    Full Text Available INTRODUCTION: In recent years, hantavirus infections producing severe diseases have obtained an increased attention from public health authorities from the countries of Eurasia to the Americas. Brazil has reported 1,300 cases of hantavirus cardiopulmonary syndrome (HCPS from 1993 to 2010, with about 80 of them occurring in the northeast of the State of São Paulo, with 48% fatality rate. Araraquara virus was the causative agent of HCPS in the region. Considering that hantaviruses causing human disease in the Americas were unknown until 1993, we have looked for hantavirus infections in the population of Cássia dos Coqueiros county, northeast of the State of São Paulo, Brazil, before this time. This county has about 2,800 inhabitants and an economy based on agriculture, including cultivation of Brachiaria decumbens grass. The grass seeds are an important rodent attraction, facilitating transmission of hantavirus to man. Four HCPS cases were reported so far in the county. METHODS: In this study, 1,876 sera collected from 1987 to 1990 were tested for IgG to hantavirus by IgG-ELISA, using the N recombinant protein of Araraquara virus as antigen. RESULTS: Positive results were observed in 89 (4.7% samples, which were all collected in 1987. The positivity among urban inhabitants was 5.3%, compared with 4.3% among those living in rural areas. CONCLUSIONS: Our results showed that hantavirus infections occurred in Cássia dos Coqueiros, completely unrecognized, even before hantaviruses were described in the Americas.

  16. The fundamental role of endothelial cells in hantavirus pathogenesis

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    Jussi eHepojoki

    2014-12-01

    Full Text Available Hantavirus, a genus of rodent- and insectivore-borne viruses in the family Bunyaviridae, is a group of emerging zoonotic pathogens. Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS and hantavirus cardiopulmonary syndrome (HCPS in man, often with severe consequences. Vascular leakage is evident in severe hantavirus infections, and increased permeability contributes to the pathogenesis. This review summarizes the current knowledge on hantavirus interactions with endothelial cells, and their effects on the increased vascular permeability.

  17. The fundamental role of endothelial cells in hantavirus pathogenesis

    OpenAIRE

    Hepojoki, Jussi; Vaheri, Antti; Strandin, Tomas

    2014-01-01

    Hantavirus, a genus of rodent- and insectivore-borne viruses in the family Bunyaviridae, is a group of emerging zoonotic pathogens. Hantaviruses cause hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome in man, often with severe consequences. Vascular leakage is evident in severe hantavirus infections, and increased permeability contributes to the pathogenesis. This review summarizes the current knowledge on hantavirus interactions with hematopoietic and endothelial ...

  18. Hantaviroses Hantaviruses

    Directory of Open Access Journals (Sweden)

    Marcelo Simão Ferreira

    2003-01-01

    continent, including Brazil. Both diseases are transmitted to man through the inhalation of viral particles, which are shed in feces and urine of wild and domestic rodents. They comprise a group of febrile diseases that can affect many organs, particularly the kidneys in the hemorrhagic fever associated with renal syndrome and the lungs and heart in the hantavirus cardiopulmonary syndrome. The lethality of American hantaviroses reaches 50%. The diagnosis of these diseases is performed using serological tests such as immunoenzymatic assays which detect specific antibodies of the IgG and IgM classes. There is no specific treatment. Therefore, special attention should be directed to restore and maintain fluid balance, timely indication of dialysis for renal failure and administration of vasoactive drugs during periods of hypotension and shock. The administration of corticosteroids and/or ribavirin are under evaluation. The number of cases of hantavirus infection has been increasing in Brazil year after year, and it is important to alert health personnel to the occurrence of these entities throughout the country. Awareness of their presence should improve the quality of medical care.

  19. Prevalence of infection with hantavirus in rodent populations of central Argentina

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    Olga V Suárez

    2003-09-01

    Full Text Available We studied hantavirus seroprevalence and virus variability in rodent populations in Diego Gaynor, northwest of Buenos Aires province, Argentina. Rodent samplings were conducted in railroads and cropfield borders in March and July 1999, September and December 2000, and March 2001. Antibody detection was performed by an enzyme link immunosorbent assay (ELISA, using the recombinant nucleoprotein of Andes (AND virus as antigen. Tissue samples were taken from positive antibody individuals in order to confirm the presence of hantavirus genomic material and to identify virus genotypes. Akodon azarae was the most abundant species, followed by Oligoryzomys flavescens, while Calomys laucha and C. musculinus were rarely caught. We found a rate of seroprevalence of 9.3% for a total sample of 291 A. azarae and 13.5% for 37 O. flavescens. After molecular analyses of hantavirus, we confirmed the presence of hantavirus genomic material in 16 individuals with ELISA (+ results and two individuals with ELISA (-. Four amplimers for each species were sequenced and compared to the corresponding sequences of representative hantaviruses. We identified the AND Cent Lec from three O. flavescens, and the Pergamino virus from four A. azarae and from one O. flavescens. A. azarae males had higher seroprevalence than females, and heavier individuals showed higher seroprevalence than lighter ones. We did not find seroprevalence differences according to sex in O. flavescens, although this result may have been produced by the low sample size. The lowest seroprevalence was found in a period of high rodent density, when juveniles prevailed in the population. We found higher seroprevalences than those detected in previous studies for other localities of central Argentina where cases of hantavirus pulmonary syndrome (HPS have been reported. The presence of AND Cent Lec virus in rodent populations of the study area, which is responsible of HPS cases in central Argentina, suggests

  20. A Nonfatal Case of Dobrava Hantavirus Hemorrhagic Fever with Renal Syndrome Combined with Hantavirus Cardiopulmonary Syndrome

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    Shemsedin Dreshaj

    2018-01-01

    Full Text Available Among hantaviruses (HTNV, 22 are known as pathogenic for humans. HTNV can cause two clinical entities: hemorrhagic fever with renal syndrome (HFRS and hantavirus pulmonary syndrome or hantavirus cardiopulmonary syndrome (HCPS. In most countries of Eastern Europe as well as in Kosovo, HTNV infection is presented mainly as HFRS. Here, we report a 20-year-old man with HFRS and HCPS caused by Dobrava hantavirus strain, successfully treated in Intensive Care Unit of Infectious Diseases Clinic, University Clinical Center of Kosovo. In HFRS endemic areas, patients with acute respiratory distress syndrome need to be evaluated for Dobrava hantavirus strain as a possible causative agent.

  1. A non-fatal case of hantavirus cardiopulmonary syndrome imported into the UK (ex Panama), July 2014

    OpenAIRE

    Atkinson, Barry; Jameson, Lisa J.; Bovill, Bego?a A.; Aarons, Emma J.; Clewlow, Jodie; Lumley, Sarah; Latham, Jennie; Jenkins, Megan H.; MacGowan, Alasdair P.; Simpson, Andrew J.; Ahmed, Javeed; Brooks, Timothy J.; Hewson, Roger

    2015-01-01

    Highlights ? Detection of hantavirus cardiopulmonary syndrome imported into Europe. ? Additional evidence that Choclo hantavirus is currently circulating and causing human disease in Panama. ? Novel diagnostic and sequencing assays for identifying cases of Choclo hantavirus infection.

  2. [Nephropathy due to Puumala hantavirus].

    Science.gov (United States)

    Dandolo, A; Prajs, N; Lizop, M

    2014-12-01

    Hemorrhagic fever with renal syndrome (HFRS) is due to an infection by the virus of the Hantavirus genus. Rodent hosts of Hantavirus are present in restricted areas in France; consequently, there are ecological niches and microepidemics of human Hantavirus infections. A HFRS case was diagnosed in the Paris region. The 11-year-old child had an acute debut fever-persistent despite antipyretic medication-asthenia, headache, abdominal pain, myalgia, thrombocytopenia, as well as renal failure with proteinuria. The diagnosis was made with a relevant clinical history and the specific serology of Puumala hantavirus. Therefore, a kidney biopsy was not necessary. What was interesting was the diagnostic approach because of the difference between the place and time of contamination and where the child became ill and developed the symptoms. The child was infected by Puumala hantavirus in Les Ardennes, a high-risk area, but became ill in the Paris region, an area with no prevalence. We review Hantavirus infections in France and its differential diagnosis. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  3. Hemorrhagic fever with renal syndrome and coexisting hantavirus pulmonary syndrome

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    Young Min Hong

    2012-06-01

    Full Text Available Hemorrhagic fever with renal syndrome (HFRS is an acute viral disease with fever, hemorrhage and renal failure caused by hantavirus infection. Hantavirus induces HFRS or hantavirus pulmonary syndrome (HPS. HPS progression to a life-threatening pulmonary disease is found primarily in the USA and very rarely in South Korea. Here, we report a case of HFRS and coexisting HPS.

  4. Concomitant influence of helminth infection and landscape on the distribution of Puumala hantavirus in its reservoir, Myodes glareolus.

    Science.gov (United States)

    Salvador, Alexis Ribas; Guivier, Emmanuel; Xuéreb, Anne; Chaval, Yannick; Cadet, Patrice; Poulle, Marie-Lazarine; Sironen, Tarja; Voutilainen, Liina; Henttonen, Heikki; Cosson, Jean-François; Charbonnel, Nathalie

    2011-02-08

    Puumala virus, the agent of nephropathia epidemica (NE), is the most prevalent hantavirus in Europe. The risk for human infection seems to be strongly correlated with the prevalence of Puumala virus (PUUV) in populations of its reservoir host species, the bank vole Myodes glareolus. In humans, the infection risks of major viral diseases are affected by the presence of helminth infections. We therefore proposed to analyse the influence of both helminth community and landscape on the prevalence of PUUV among bank vole populations in the Ardennes, a PUUV endemic area in France. Among the 313 voles analysed, 37 had anti-PUUV antibodies. Twelve gastro-intestinal helminth species were recorded among all voles sampled. We showed that PUUV seroprevalence strongly increased with age or sexual maturity, especially in the northern forests (massif des Ardennes). The helminth community structure significantly differed between this part and the woods or hedgerows of the southern cretes pre-ardennaises. Using PUUV RNA quantification, we identified significant coinfections between PUUV and gastro-intestinal helminths in the northern forests only. More specifically, PUUV infection was positively associated with the presence of Heligmosomum mixtum, and in a lesser extent, Aonchotheca muris-sylvatici. The viral load of PUUV infected individuals tended to be higher in voles coinfected with H. mixtum. It was significantly lower in voles coinfected with A. muris-sylvatici, reflecting the influence of age on these latter infections. This is the first study to emphasize hantavirus--helminth coinfections in natural populations. It also highlights the importance to consider landscape when searching for such associations. We have shown that landscape characteristics strongly influence helminth community structure as well as PUUV distribution. False associations might therefore be evidenced if geographic patterns of helminths or PUUV repartition are not previously identified. Moreover, our

  5. Concomitant influence of helminth infection and landscape on the distribution of Puumala hantavirus in its reservoir, Myodes glareolus

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    Henttonen Heikki

    2011-02-01

    Full Text Available Abstract Background Puumala virus, the agent of nephropathia epidemica (NE, is the most prevalent hantavirus in Europe. The risk for human infection seems to be strongly correlated with the prevalence of Puumala virus (PUUV in populations of its reservoir host species, the bank vole Myodes glareolus. In humans, the infection risks of major viral diseases are affected by the presence of helminth infections. We therefore proposed to analyse the influence of both helminth community and landscape on the prevalence of PUUV among bank vole populations in the Ardennes, a PUUV endemic area in France. Results Among the 313 voles analysed, 37 had anti-PUUV antibodies. Twelve gastro-intestinal helminth species were recorded among all voles sampled. We showed that PUUV seroprevalence strongly increased with age or sexual maturity, especially in the northern forests (massif des Ardennes. The helminth community structure significantly differed between this part and the woods or hedgerows of the southern cretes pre-ardennaises. Using PUUV RNA quantification, we identified significant coinfections between PUUV and gastro-intestinal helminths in the northern forests only. More specifically, PUUV infection was positively associated with the presence of Heligmosomum mixtum, and in a lesser extent, Aonchotheca muris-sylvatici. The viral load of PUUV infected individuals tended to be higher in voles coinfected with H. mixtum. It was significantly lower in voles coinfected with A. muris-sylvatici, reflecting the influence of age on these latter infections. Conclusions This is the first study to emphasize hantavirus - helminth coinfections in natural populations. It also highlights the importance to consider landscape when searching for such associations. We have shown that landscape characteristics strongly influence helminth community structure as well as PUUV distribution. False associations might therefore be evidenced if geographic patterns of helminths or PUUV

  6. Highly differentiated, resting gn-specific memory CD8+ T cells persist years after infection by andes hantavirus.

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    Tobias Manigold

    2010-02-01

    Full Text Available In man, infection with South American Andes virus (ANDV causes hantavirus cardiopulmonary syndrome (HCPS. HCPS due to ANDV is endemic in Southern Chile and much of Argentina and increasing numbers of cases are reported all over South America. A case-fatality rate of about 36% together with the absence of successful antiviral therapies urge the development of a vaccine. Although T-cell responses were shown to be critically involved in immunity to hantaviruses in mouse models, no data are available on the magnitude, specificity and longevity of ANDV-specific memory T-cell responses in patients. Using sets of overlapping peptides in IFN-gamma ELISPOT assays, we herein show in 78 Chilean convalescent patients that Gn-derived epitopes were immunodominant as compared to those from the N- and Gc-proteins. Furthermore, while the relative contribution of the N-specific response significantly declined over time, Gn-specific responses remained readily detectable ex vivo up to 13 years after the acute infection. Tetramer analysis further showed that up to 16.8% of all circulating CD3(+CD8(+ T cells were specific for the single HLA-B*3501-restricted epitope Gn(465-473 years after the acute infection. Remarkably, Gn(465-473-specific cells readily secreted IFN-gamma, granzyme B and TNF-alpha but not IL-2 upon stimulation and showed a 'revertant' CD45RA(+CD27(-CD28(-CCR7(-CD127(- effector memory phenotype, thereby resembling a phenotype seen in other latent virus infections. Most intriguingly, titers of neutralizing antibodies increased over time in 10/17 individuals months to years after the acute infection and independently of whether they were residents of endemic areas or not. Thus, our data suggest intrinsic, latent antigenic stimulation of Gn-specific T-cells. However, it remains a major task for future studies to proof this hypothesis by determination of viral antigen in convalescent patients. Furthermore, it remains to be seen whether Gn-specific T

  7. Serologic survey for hantavirus infections among wild animals in rural areas of São Paulo State, Brazil

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    ROMANO-LIEBER Nicolina Silvana

    2001-01-01

    Full Text Available A serosurvey was conducted in wild animals captured close to two areas where hantavirus cardiopulmonary syndrome (HCPS occurred in São Paulo State, Brazil. Serum samples from a total of 43 mammals were tested for antibodies reactive with Sin Nombre (SN hantavirus using a strip immunoblot assay. RNAs from the blood clots of the positive samples were submitted to reverse transcriptase-polymerase chain reaction (RT-PCR. Two rodents of the genus Oligoryzomys were positive for hantavirus antibodies. These animals were captured in the Iguape region and represented 16.7% (2/12 of the sera from rodents and 100.0% (2/2 of the Oligoryzomys captured in that area. RT-PCR failed to amplify any viral cDNA. These results are in agreement with other data that suggest that members of this genus are important reservoirs of hantaviruses in Brazil.

  8. Cases of Clinically Proven Hantavirus Infection with a Pulmonary Syndrome among Pregnant Women in Tashkent, Uzbekistan

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    Andrey V. An

    2012-12-01

    Full Text Available Background: For nearly a decade, a disease likely to have been misdiagnosed was observed in pregnant women in Tashkent, Uzbekistan. It caused the rapid decline and death of patients, with about 45% mortality rate. The disease was suspected to be caused by a virus of the HVP (Hantavirus family, and clinical studies were conducted to ascertain. Methods: As no system for registration of such cases had been maintained, researchers developed a questionnaire with indicators chiefly based on relevant literature. All the women admitted exhibiting the symptoms listed were covered by the study. Results: Among the 16 cases identified from September to December 2008, ten survived; 80% belonged to the indigenous ethnic group; 80% were housewives. Most (90% were between 16 and 34 weeks’ pregnancy, 24.5 weeks on average. Almost all of them experienced labored breathing and abnormally high body temperature. About 75% of the women lived in the vicinity of rodents’ habitats, and about half of them could have been in direct contact with the aerosolized rodent excreta. Conclusions: Researchers believe that those women exposed to the excreta were cases of HPS. In practice, the surgical removal of the fetus proved to be the most efficient treatment. However, the medical community has a growing concern about patients with HPV being misdiagnosed and the related difficulties in diagnosing and treating them.

  9. Hantavirus Pulmonary Syndrome (HPS)

    Science.gov (United States)

    ... to Yosemite FAQ: Non-U.S. Visitors to Yosemite History of HPS Related Links Prevent Rodent Infestations Cleaning Up After Rodents Diseases From Rodent Hantavirus Pulmonary Syndrome (HPS) Recommend on Facebook Tweet Share Compartir Hantavirus Pulmonary Syndrome (HPS) is ...

  10. A retrospective serologic survey of hantavirus infections in the county of Cássia dos Coqueiros, State of São Paulo, Brazil Inquérito sorológico retrospectivo das infecções por hantavirus no município de Cássia dos Coqueiros, Estado de São Paulo, Brasil

    Directory of Open Access Journals (Sweden)

    Soraya Jabur Badra

    2012-08-01

    Full Text Available INTRODUCTION: In recent years, hantavirus infections producing severe diseases have obtained an increased attention from public health authorities from the countries of Eurasia to the Americas. Brazil has reported 1,300 cases of hantavirus cardiopulmonary syndrome (HCPS from 1993 to 2010, with about 80 of them occurring in the northeast of the State of São Paulo, with 48% fatality rate. Araraquara virus was the causative agent of HCPS in the region. Considering that hantaviruses causing human disease in the Americas were unknown until 1993, we have looked for hantavirus infections in the population of Cássia dos Coqueiros county, northeast of the State of São Paulo, Brazil, before this time. This county has about 2,800 inhabitants and an economy based on agriculture, including cultivation of Brachiaria decumbens grass. The grass seeds are an important rodent attraction, facilitating transmission of hantavirus to man. Four HCPS cases were reported so far in the county. METHODS: In this study, 1,876 sera collected from 1987 to 1990 were tested for IgG to hantavirus by IgG-ELISA, using the N recombinant protein of Araraquara virus as antigen. RESULTS: Positive results were observed in 89 (4.7% samples, which were all collected in 1987. The positivity among urban inhabitants was 5.3%, compared with 4.3% among those living in rural areas. CONCLUSIONS: Our results showed that hantavirus infections occurred in Cássia dos Coqueiros, completely unrecognized, even before hantaviruses were described in the Americas.INTRODUÇÃO: Infecções graves por hantavírus têm obtido crescente atenção das autoridades da saúde pública da Eurásia e Américas. De 1993 a 2010, o Brasil reportou 1.300 casos de síndrome pulmonar cardiovascular por hantavírus (SPCVH com, aproximadamente, 80 deles no nordeste do Estado de São Paulo com taxa de fatalidade de 48%. O vírus Araraquara é o agente etiológico da SPCVH nessa região. Considerando que nas Am

  11. Globally emerging hantaviruses: An overview

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    Sara Chandy

    2017-01-01

    Full Text Available Hantaviruses are known to cause haemorrhagic fever with renal syndrome in Eurasia and hantavirus cardiopulmonary syndrome in the Americas. They are globally emerging pathogens as newer serotypes are routinely being reported. This review discusses hantavirus biology, clinical features and pathogenesis of hantavirus disease, its diagnostics, distribution and mammalian hosts. Hantavirus research in India is also summarised.

  12. A case-control study after a hantavirus infection outbreak in the south of Belgium: who is at risk?

    Science.gov (United States)

    Van Loock, F; Thomas, I; Clement, J; Ghoos, S; Colson, P

    1999-04-01

    Puumala is the most common hantavirus serotype in Europe and is spread mainly by the red bank vole. Between 1 July 1992 and 31 January 1994, an outbreak of Puumala virus-induced nephropathia epidemica (NE) occurred in the Belgian Ardennes. Serologically confirmed cases (n = 41) were compared with two groups of asymptomatic seronegative controls. Risks identified included sighting of living rodents, exposure to rodent droppings, and trapping rodents during the 4 weeks preceding onset of symptoms. Activities during this 4-week period that presented the greatest risk were woodcutting, reopening of a nonaerated room, and strenuous physical effort. This is the first case-control study on risk factors for NE in Europe. In comparison with the American form of hantavirus pulmonary syndrome, which is spread by deer mice, professional activity appears to be a more important risk factor for acquisition of hantavirus in Europe.

  13. Infection of human monocyte-derived dendritic cells by ANDES Hantavirus enhances pro-inflammatory state, the secretion of active MMP-9 and indirectly enhances endothelial permeability

    Directory of Open Access Journals (Sweden)

    Lopez-Lastra Marcelo

    2011-05-01

    Full Text Available Abstract Background Andes virus (ANDV, a rodent-borne Hantavirus, is the major etiological agent of Hantavirus cardiopulmonary syndrome (HCPS in South America, which is mainly characterized by a vascular leakage with high rate of fatal outcomes for infected patients. Currently, neither specific therapy nor vaccines are available against this pathogen. ANDV infects both dendritic and epithelial cells, but in despite that the severity of the disease directly correlates with the viral RNA load, considerable evidence suggests that immune mechanisms rather than direct viral cytopathology are responsible for plasma leakage in HCPS. Here, we assessed the possible effect of soluble factors, induced in viral-activated DCs, on endothelial permeability. Activated immune cells, including DC, secrete gelatinolytic matrix metalloproteases (gMMP-2 and -9 that modulate the vascular permeability for their trafficking. Methods A clinical ANDES isolate was used to infect DC derived from primary PBMC. Maturation and pro-inflammatory phenotypes of ANDES-infected DC were assessed by studying the expression of receptors, cytokines and active gMMP-9, as well as some of their functional status. The ANDES-infected DC supernatants were assessed for their capacity to enhance a monolayer endothelial permeability using primary human vascular endothelial cells (HUVEC. Results Here, we show that in vitro primary DCs infected by a clinical isolate of ANDV shed virus RNA and proteins, suggesting a competent viral replication in these cells. Moreover, this infection induces an enhanced expression of soluble pro-inflammatory factors, including TNF-α and the active gMMP-9, as well as a decreased expression of anti-inflammatory cytokines, such as IL-10 and TGF-β. These viral activated cells are less sensitive to apoptosis. Moreover, supernatants from ANDV-infected DCs were able to indirectly enhance the permeability of a monolayer of primary HUVEC. Conclusions Primary human DCs

  14. Hantavirus Pulmonary Syndrome in the United States.

    Science.gov (United States)

    Fabbri, Marilyn; Maslow, Melanie J.

    2001-06-01

    Since the first outbreak of hantavirus pulmonary syndrome (HPS) in 1993, understanding of the vast distribution and potential impact of hantaviruses has grown. At least 277 cases of HPS have been documented in the United States. The full clinical spectrum has yet to be elucidated, and one outbreak suggested the possibility of person-to-person transmission. New research has identified the b-3 integrins as cellular receptors for hantaviruses and has determined the pivotal role of the immune system in pathogenesis. Rapid diagnosis has been facilitated by a new immunoblot assay to detect Sin Nombre virus infection. Treatment remains primarily supportive; however, a placebo- controlled trial of ribavirin is ongoing. Extracorporeal membrane oxygenation may be a potential therapy in severe cases; inhaled nitric oxide needs further study. Vaccines developed against hantaviruses associated with hemorrhagic fever and renal syndrome might be effective against HPS-associated strains.

  15. Temporal variation in individual factors associated with hantavirus infection in bank voles during an epizootic: implications for Puumala virus transmission dynamics.

    Science.gov (United States)

    Tersago, Katrien; Verhagen, Ron; Leirs, Herwig

    2011-06-01

    Puumala virus (PUUV), the causal agent of nephropathia epidemica in humans, is one of the many hantaviruses included in the list of emerging pathogens. Hantavirus infection is not distributed evenly among PUUV reservoir hosts (i.e., bank voles [Myodes glareolus]). Besides environmental factors and local population features, individual characteristics play an important role in vole PUUV infection risk. Identifying the relative importance of these individual characteristics can provide crucial information on PUUV transmission processes. In the present study, bank voles were monitored during the nephropathia epidemica outbreak of 2005 in Belgium. Vole sera were tested for presence of immunoglobulin G against PUUV, and a logistic mixed model was built to investigate the temporal variation in individual characteristics and their relative importance to PUUV infection risk in bank voles. Relative risk calculations for individual vole characteristics related to PUUV infection in the reservoir host show that reproductive activity dominates infection risk. The gender effect is only found in reproductively active voles, where reproductively active males have the highest infection risk. Results also revealed a clear seasonal variation in the importance of reproductive activity linked to PUUV infection. In contrast to the main effect found in other trapping sessions, no difference in infection risk ratio was found between reproductively active and nonactive voles in the spring period. Combined with increased infection risk for the reproductively nonactive group at that time, these results indicate a shift in the transmission process due to changes in bank vole behavior, physiology, or climate conditions. Hence, our results suggest that mathematical models should take into account seasonal shifts in transmission mechanisms. When these results are combined with the seasonal changes in population structure during the epizootic period, we identify vole reproductive activity and

  16. Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil

    Directory of Open Access Journals (Sweden)

    William Marciel de Souza

    2012-08-01

    Full Text Available Hantavirus cardiopulmonary syndrome (HCPS is an infectious disease caused by hantaviruses of the family Bunyaviridae, and is transmitted by aerosols of excreta of infected rodents. The aim of the present study was to determine antibody levels to hantavirus in the population that lives at frontier of Brazil and Argentina. Participated of the study 405 individuals living in the municipalities of Bandeirante, Santa Helena, Princesa and Tunapolis, state of Santa Catarina, Brazil. IgG antibodies to hantavirus were analyzed in sera by an ELISA that uses a recombinant N protein of Araraquara hantavirus as antigen. The results were also confirmed by immunofluorescent test. Eight individuals showed antibodies to hantavirus (1.97% positivity, with serum titers ranging from 100 to 800. Six seropositives were males, older than 30 years and farmers. Our results reinforce previous data on hantavirus circulation and human infections in the southern border of Brazil with Argentina.

  17. Hantavirus Outbreak: The Qualitative Study

    Directory of Open Access Journals (Sweden)

    Funda Sevencan

    2012-02-01

    Full Text Available Aim: In this study, it was aimed to research by means of qualitative research methods the contact of individuals living in the region with mice and wild animals during the examination of Hantavirus epidemic to produce. Materials and Methods: In the interviews, the contact of participants with mice and wild animals, their opinions about the climate change and their symptom history pertaining to Hantavirus infections in themselves or relatives were discussed. Results: The participants stated that they didn’t see any mouse or mouse excretion, however that they encountered such cases in areas such as woodbin, roof, terrace, forest, etc. all interviews, the increase in the number of wild boars and jackals was especially stated. In all interviews, it was stated that this year was more rainy and warmer compared to previous years. Conclusion: The findings of the study give the impression that the participant group is under the risk of Hantavirus infection. [TAF Prev Med Bull 2012; 11(1.000: 81-86

  18. Effect of Puumala hantavirus infection on Human Umbilical Vein Endothelial Cell hemostatic function: platelet interactions, increased tissue factor expression and fibrinolysis regulator release

    Directory of Open Access Journals (Sweden)

    Marco Goeijenbier

    2015-03-01

    Full Text Available Puumala virus (PUUV infection causes over 5000 cases of hemorrhagic fever in Europe annually and can influence the hemostatic balance extensively. Infection might lead to hemorrhage, while a recent study showed an increased risk of myocardial infarction during or shortly after PUUV infection. The mechanism by which this hantavirus influences the coagulation system remains unknown. Therefore we aimed to elucidate mechanisms explaining alterations seen in primary and secondary hemostasis during PUUV infection. By using low passage PUUV isolates to infect primary human umbilical vein endothelial cells (HUVECs we were able to show alterations in the regulation of primary- and secondary hemostasis and in the release of fibrinolysis regulators. Our main finding was an activation of secondary hemostasis due to increased tissue factor expression leading to increased thrombin generation in a functional assay. Furthermore, we showed that during infection platelets adhered to HUVECs and subsequently specifically to PUUV virus particles. Infection of HUVECs with PUUV did not result in increased von Willebrand factor while they produced more plasminogen activator inhibitor type-1 (PAI-1 compared to controls. The PAI-1 produced in this model formed complexes with vitronectin. This is the first report that reveals a potential mechanism behind the pro-coagulant changes in PUUV patients, which could be the result of increased thrombin generation due to an increased tissue factor expression on endothelial cells during infection. Furthermore, we provide insight into the contribution of endothelial cell responses regarding hemostasis in PUUV pathogenesis.

  19. Hantavirus Immunology of Rodent Reservoirs: Current Status and Future Directions

    Directory of Open Access Journals (Sweden)

    Tony Schountz

    2014-03-01

    Full Text Available Hantaviruses are hosted by rodents, insectivores and bats. Several rodent-borne hantaviruses cause two diseases that share many features in humans, hemorrhagic fever with renal syndrome in Eurasia or hantavirus cardiopulmonary syndrome in the Americas. It is thought that the immune response plays a significant contributory role in these diseases. However, in reservoir hosts that have been closely examined, little or no pathology occurs and infection is persistent despite evidence of adaptive immune responses. Because most hantavirus reservoirs are not model organisms, it is difficult to conduct meaningful experiments that might shed light on how the viruses evade sterilizing immune responses and why immunopathology does not occur. Despite these limitations, recent advances in instrumentation and bioinformatics will have a dramatic impact on understanding reservoir host responses to hantaviruses by employing a systems biology approach to identify important pathways that mediate virus/reservoir relationships.

  20. Sweden

    International Nuclear Information System (INIS)

    2011-01-01

    The Swedish nuclear industry is - like in many countries - in a state of rejuvenation. During the coming ten years, 6000 new staff will be employed, which in volume corresponds to the entire present industry. These numbers are based on retirements (easy to estimate), increased needs due to new-build, and to increased mobility of the new staff to be employed (more difficult to estimate). Until now, employment in nuclear power have often lasted very long. We anticipate, however, that the young people that will be recruited will be less prone to stay at the same place for long. Until now, Sweden has never had a dedicated bachelor level nuclear engineering programme. This will, however, change. A new programme will start at Uppsala University in autumn 2010. An existing 3-year bachelor-level mechanics engineering education programme will get a third-year specialization in nuclear engineering. This specialization has been designed to allow students from any technical college or university in Sweden with mechanical or electric engineering in the curriculum. The studies will be in Swedish. Industry is involved both as sponsors and as contributors. The industry educational company (KSU) is closely involved, e.g. with simulator training. The Royal Institute of Technology (KTH), Stockholm, has offered an international MSc in nuclear engineering since 2008. The programme has attracted 10-15 students per year. In addition, students at other programmes participate in some courses, resulting in about 25 students in an average course. Chalmers Institute of Technology, Gothenburg, has started a new nuclear engineering MSc programme in autumn 2009. The programme has equal shares of reactor physics/technology and nuclear chemistry, reflecting the competence profile at Chalmers. This special curriculum is highly appreciated by the Ringhals nuclear power plant nearby, that houses three PWRs, and needs staff with combined reactor physics and nuclear chemistry competence. Uppsala

  1. Potential geographic distribution of hantavirus reservoirs in Brazil.

    Directory of Open Access Journals (Sweden)

    Stefan Vilges de Oliveira

    Full Text Available Hantavirus cardiopulmonary syndrome is an emerging zoonosis in Brazil. Human infections occur via inhalation of aerosolized viral particles from excreta of infected wild rodents. Necromys lasiurus and Oligoryzomys nigripes appear to be the main reservoirs of hantavirus in the Atlantic Forest and Cerrado biomes. We estimated and compared ecological niches of the two rodent species, and analyzed environmental factors influencing their occurrence, to understand the geography of hantavirus transmission. N. lasiurus showed a wide potential distribution in Brazil, in the Cerrado, Caatinga, and Atlantic Forest biomes. Highest climate suitability for O. nigripes was observed along the Brazilian Atlantic coast. Maximum temperature in the warmest months and annual precipitation were the variables that most influence the distributions of N. lasiurus and O. nigripes, respectively. Models based on occurrences of infected rodents estimated a broader area of risk for hantavirus transmission in southeastern and southern Brazil, coinciding with the distribution of human cases of hantavirus cardiopulmonary syndrome. We found no demonstrable environmental differences among occurrence sites for the rodents and for human cases of hantavirus. However, areas of northern and northeastern Brazil are also apparently suitable for the two species, without broad coincidence with human cases. Modeling of niches and distributions of rodent reservoirs indicates potential for transmission of hantavirus across virtually all of Brazil outside the Amazon Basin.

  2. Hantavirus cardiopulmonary syndrome: a report of two cases

    OpenAIRE

    Marcos Lazaro Moreli; Vivaldo Gomes da Costa; Daiane Pereira da Silva Novaes; Enia Cristina Flor; Juliana Freitas Silva; Keila Rejane Guimarães Vilela; Cácia Régia de Paula

    2013-01-01

    Infection with hantavirus, from the family Bunyaviridae, causes hantavirus cardiopulmonary syndrome (HCPS) in the Americas. This highly lethal anthropozoonosis afflicts preferentially individuals in rural areas and is transmitted by aerosol of excreta from infected wild rodents. The aim of this study is to report the almost simultaneous occurrence of two cases of HCPS in the municipality of Jataí, state of Goiás, Brazil.

  3. Hantavirus cardiopulmonary syndrome: a report of two cases

    Directory of Open Access Journals (Sweden)

    Marcos Lazaro Moreli

    2013-10-01

    Full Text Available Infection with hantavirus, from the family Bunyaviridae, causes hantavirus cardiopulmonary syndrome (HCPS in the Americas. This highly lethal anthropozoonosis afflicts preferentially individuals in rural areas and is transmitted by aerosol of excreta from infected wild rodents. The aim of this study is to report the almost simultaneous occurrence of two cases of HCPS in the municipality of Jataí, state of Goiás, Brazil.

  4. Two Decades of Hantavirus

    Centers for Disease Control (CDC) Podcasts

    2017-06-29

    Dr. de St. Maurice, a CDC Epidemic Intelligence Service officer, discusses hantavirus.  Created: 6/29/2017 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 6/29/2017.

  5. Hantavirus Pulmonary Syndrome in Santa Cruz, Bolivia: Outbreak Investigation and Antibody Prevalence Study

    Science.gov (United States)

    2012-10-18

    Ecology and epidemiology of an emerging virus in Latin America]. Medicina (B Aires) 66: 343–356. 22. Weissenbacher MC, Cura E, Segura EL, Hortal M, Baek LJ...et al. (1996) Serological evidence of human Hantavirus infection in Argentina, Bolivia and Uruguay. Medicina (B Aires) 56: 17–22. 23. Pini N (2004...Hantavirus in human and rodent population in an endemic area for hantavirus pulmonary syndrome in Argentina]. Medicina (B Aires) 62: 1–8. 26. Simonsen L

  6. Structure of the Hantavirus Nucleoprotein Provides Insights into the Mechanism of RNA Encapsidation

    Directory of Open Access Journals (Sweden)

    Daniel Olal

    2016-03-01

    Full Text Available Hantaviruses are etiological agents of life-threatening hemorrhagic fever with renal syndrome and hantavirus cardiopulmonary syndrome. The nucleoprotein (N of hantavirus is essential for viral transcription and replication, thus representing an attractive target for therapeutic intervention. We have determined the crystal structure of hantavirus N to 3.2 Å resolution. The structure reveals a two-lobed, mostly α-helical structure that is distantly related to that of orthobunyavirus Ns. A basic RNA binding pocket is located at the intersection between the two lobes. We provide evidence that oligomerization is mediated by amino- and C-terminal arms that bind to the adjacent monomers. Based on these findings, we suggest a model for the oligomeric ribonucleoprotein (RNP complex. Our structure provides mechanistic insights into RNA encapsidation in the genus Hantavirus and constitutes a template for drug discovery efforts aimed at combating hantavirus infections.

  7. Phylogeny and origins of hantaviruses harbored by bats, insectivores, and rodents.

    Directory of Open Access Journals (Sweden)

    Wen-Ping Guo

    2013-02-01

    Full Text Available Hantaviruses are among the most important zoonotic pathogens of humans and the subject of heightened global attention. Despite the importance of hantaviruses for public health, there is no consensus on their evolutionary history and especially the frequency of virus-host co-divergence versus cross-species virus transmission. Documenting the extent of hantavirus biodiversity, and particularly their range of mammalian hosts, is critical to resolving this issue. Here, we describe four novel hantaviruses (Huangpi virus, Lianghe virus, Longquan virus, and Yakeshi virus sampled from bats and shrews in China, and which are distinct from other known hantaviruses. Huangpi virus was found in Pipistrellus abramus, Lianghe virus in Anourosorex squamipes, Longquan virus in Rhinolophus affinis, Rhinolophus sinicus, and Rhinolophus monoceros, and Yakeshi virus in Sorex isodon, respectively. A phylogenetic analysis of the available diversity of hantaviruses reveals the existence of four phylogroups that infect a range of mammalian hosts, as well as the occurrence of ancient reassortment events between the phylogroups. Notably, the phylogenetic histories of the viruses are not always congruent with those of their hosts, suggesting that cross-species transmission has played a major role during hantavirus evolution and at all taxonomic levels, although we also noted some evidence for virus-host co-divergence. Our phylogenetic analysis also suggests that hantaviruses might have first appeared in Chiroptera (bats or Soricomorpha (moles and shrews, before emerging in rodent species. Overall, these data indicate that bats are likely to be important natural reservoir hosts of hantaviruses.

  8. What Do We Know about How Hantaviruses Interact with Their Different Hosts?

    Directory of Open Access Journals (Sweden)

    Myriam Ermonval

    2016-08-01

    Full Text Available Hantaviruses, like other members of the Bunyaviridae family, are emerging viruses that are able to cause hemorrhagic fevers. Occasional transmission to humans is due to inhalation of contaminated aerosolized excreta from infected rodents. Hantaviruses are asymptomatic in their rodent or insectivore natural hosts with which they have co-evolved for millions of years. In contrast, hantaviruses cause different pathologies in humans with varying mortality rates, depending on the hantavirus species and its geographic origin. Cases of hemorrhagic fever with renal syndrome (HFRS have been reported in Europe and Asia, while hantavirus cardiopulmonary syndromes (HCPS are observed in the Americas. In some cases, diseases caused by Old World hantaviruses exhibit HCPS-like symptoms. Although the etiologic agents of HFRS were identified in the early 1980s, the way hantaviruses interact with their different hosts still remains elusive. What are the entry receptors? How do hantaviruses propagate in the organism and how do they cope with the immune system? This review summarizes recent data documenting interactions established by pathogenic and nonpathogenic hantaviruses with their natural or human hosts that could highlight their different outcomes.

  9. Hantavirus Pulmonary Syndrome

    Centers for Disease Control (CDC) Podcasts

    2011-07-14

    Dr. Adam MacNeil, epidemiologist with Viral Special Pathogens Branch at CDC, discusses hantavirus pulmonary syndrome.  Created: 7/14/2011 by National Center for Emerging Zoonotic and Infectious Diseases (NCEZID).   Date Released: 7/18/2011.

  10. Seropositivity diagnosis for hantavirus in Jataí, Goiás State, Brazil

    Directory of Open Access Journals (Sweden)

    Marcos Lázaro Moreli

    Full Text Available Abstract INTRODUCTION: Emerging diseases are of great interest, especially those associated with high mortality rates such as hantaviruses. We aimed to conduct a seroepidemiological survey to determine the levels of hantavirus infection. METHODS: In-house enzyme-linked immunosorbent assay (ELISA was used to detect specific antibodies. RESULTS: Of the 429 samples collected, seropositivity of 3.9% to anti-hantavirus immunoglobulin G (IgG was observed (CI 95%: 2.3-5.7. Moreover, in three cases, immunoglobulin M (IgM was detected, of which two were diagnosed as hantavirus cardiopulmonary syndrome (HCPS. CONCLUSIONS: Our data indicate the considerable occurrence of previous hantavirus infections, highlighting occurrences from sub-clinical cases to HCPS.

  11. Prevalence of serum antibodies to hantavirus in a rural population from the southern state of Santa Catarina, Brazil

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    Gregório Wrublevski Pereira

    2012-02-01

    Full Text Available INTRODUCTION: Rodent-borne hantaviruses cause severe human diseases. We completed a serological survey of hantavirus infection in rural inhabitants of Turvo County, in the southern State of Santa Catarina, Brazil, in which seropositivity for hantavirus was correlated to previous disease in the participants. METHODS: The levels of IgG antibodies to hantavirus Araraquara in the sera of 257 individuals were determined using an immunoenzymatic assay. RESULTS: IgG antibodies to hantavirus were found in 2.3% of the participants. All seropositive participants reported previous disease with symptoms suggestive of hantavirus cardiopulmonary syndrome. CONCLUSIONS: Human infections causing unreported cardiopulmonary syndrome probably occur in the southern State of Santa Catarina.

  12. Maporal Hantavirus Causes Mild Pathology in Deer Mice (Peromyscus maniculatus

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    Amanda McGuire

    2016-10-01

    Full Text Available Rodent-borne hantaviruses can cause two human diseases with many pathological similarities: hantavirus cardiopulmonary syndrome (HCPS in the western hemisphere and hemorrhagic fever with renal syndrome in the eastern hemisphere. Each virus is hosted by specific reservoir species without conspicuous disease. HCPS-causing hantaviruses require animal biosafety level-4 (ABSL-4 containment, which substantially limits experimental research of interactions between the viruses and their reservoir hosts. Maporal virus (MAPV is a South American hantavirus not known to cause disease in humans, thus it can be manipulated under ABSL-3 conditions. The aim of this study was to develop an ABSL-3 hantavirus infection model using the deer mouse (Peromyscus maniculatus, the natural reservoir host of Sin Nombre virus (SNV, and a virus that is pathogenic in another animal model to examine immune response of a reservoir host species. Deer mice were inoculated with MAPV, and viral RNA was detected in several organs of all deer mice during the 56 day experiment. Infected animals generated both nucleocapsid-specific and neutralizing antibodies. Histopathological lesions were minimal to mild with the peak of the lesions detected at 7–14 days postinfection, mainly in the lungs, heart, and liver. Low to modest levels of cytokine gene expression were detected in spleens and lungs of infected deer mice, and deer mouse primary pulmonary cells generated with endothelial cell growth factors were susceptible to MAPV with viral RNA accumulating in the cellular fraction compared to infected Vero cells. Most features resembled that of SNV infection of deer mice, suggesting this model may be an ABSL-3 surrogate for studying the host response of a New World hantavirus reservoir.

  13. Hantavirus pulmonary syndrome and rodent reservoirs in the savanna-like biome of Brazil's southeastern region.

    Science.gov (United States)

    Limongi, J E; Oliveira, R C; Guterres, A; Costa Neto, S F; Fernandes, J; Vicente, L H B; Coelho, M G; Ramos, V N; Ferreira, M S; Bonvicino, C R; D'Andrea, P S; Lemos, E R S

    2016-04-01

    This paper describes the diversity of rodent fauna in an area endemic for hantavirus cardiopulmonary syndrome (HCPS) in Brazil, the population dynamics and the relationship of rodents with hantavirus in the Cerrado (savanna-like) biome. Additionally, an analysis is made of the partial S segment sequences of the hantaviruses obtained from serologically confirmed human HCPS cases and from rodent specimens. Rodents were collected during four campaigns. Human serum samples were collected from suspected cases of HCPS at hospitals in the state of Minas Gerais. The samples antibody-reactive by ELISA were processed by RT-PCR. The PCR product was amplified and sequenced. Hantavirus was detected only in Necromys lasiurus, the wild rodent species most prevalent in the Cerrado biome (min-max: 50-83·7%). All the six human serum samples were hantavirus seropositive and five showed amplified PCR products. The analysis of the nucleotide sequences showed the circulation of a single genotype, the Araraquara hantavirus. The environmental changes that have occurred in the Cerrado biome in recent decades have favoured N. lasiurus in interspecific competition of habitats, thus increasing the risk of contact between humans and rodent species infected with hantavirus. Our data corroborate the definition of N. lasiurus as the main hantavirus reservoir in the Cerrado biome.

  14. Hantavirus Reservoirs: Current Status with an Emphasis on Data from Brazil

    Directory of Open Access Journals (Sweden)

    Renata Carvalho de Oliveira

    2014-04-01

    Full Text Available Since the recognition of hantavirus as the agent responsible for haemorrhagic fever in Eurasia in the 1970s and, 20 years later, the descovery of hantavirus pulmonary syndrome in the Americas, the genus Hantavirus has been continually described throughout the World in a variety of wild animals. The diversity of wild animals infected with hantaviruses has only recently come into focus as a result of expanded wildlife studies. The known reservoirs are more than 80, belonging to 51 species of rodents, 7 bats (order Chiroptera and 20 shrews and moles (order Soricomorpha. More than 80genetically related viruses have been classified within Hantavirus genus; 25 recognized as human pathogens responsible for a large spectrum of diseases in the Old and New World. In Brazil, where the diversity of mammals and especially rodents is considered one of the largest in the world, 9 hantavirus genotypes have been identified in 12 rodent species belonging to the genus Akodon, Calomys, Holochilus, Oligoryzomys, Oxymycterus, Necromys and Rattus. Considering the increasing number of animals that have been implicated as reservoirs of different hantaviruses, the understanding of this diversity is important for evaluating the risk of distinct hantavirus species as human pathogens.

  15. Hantavirus pulmonary syndrome (rio Mamore virus) in the peruvian Amazon region

    OpenAIRE

    Mamani, Enrique; Centro Nacional de Salud Pública. Instituto Nacional de Salud. Lima, Perú. biólogo.; García, María P.; Centro Nacional de Salud Pública. Instituto Nacional de Salud. Lima, Perú. tecnólogo médico.; Miraval, María L.; Centro Nacional de Salud Pública. Instituto Nacional de Salud. Lima, Perú. médico anátomo-patólogo.; Valencia, Pedro; Centro Nacional de Salud Pública. Instituto Nacional de Salud. Lima, Perú. Médico infectólogo.; Quino, Alberto H.; Hospital Regional de Loreto, Gobierno Regional de Loreto. Loreto, Perú. médico intensivista.; Álvarez, Carlos; Unidad de Análisis y Generación de Evidencias en Salud Pública. Instituto Nacional de Salud. Lima, Perú. médico anátomo-patólogo.; Donaires, Luis F.; Dirección Regional de Salud de Loreto, Gobierno Regional de Loreto. Loreto, Perú. médico epidemiólogo.

    2014-01-01

    Hantavirus infection is a viral zoonotic infection borne by rodents which most letal form clinical is the Hantavirus Pulmonary Syndrome (SPH, Spanish abbreviation). The Mamore River variant originates in South America and was found in rodents without any association to human diseases. Two cases of SPH were identified in the Peruvian Amazon region in November 2011. In both cases, a molecular diagnostic testing was conducted by the Instituto Nacional de Salud from Peru. A phylogenetic analy...

  16. Population Ecology of Hantavirus Rodent Hosts in Southern Brazil

    Science.gov (United States)

    Teixeira, Bernardo R.; Loureiro, Nathalie; Strecht, Liana; Gentile, Rosana; Oliveira, Renata C.; Guterres, Alexandro; Fernandes, Jorlan; Mattos, Luciana H. B. V.; Raboni, Sonia M.; Rubio, Giselia; Bonvicino, Cibele R.; Duarte dos Santos, Claudia N.; Lemos, Elba R. S.; D'Andrea, Paulo S.

    2014-01-01

    In this study we analyze population dynamics of hantavirus rodent hosts and prevalence of infection over a 2-year period in Southern Brazil, a region with a high incidence of hantavirus pulmonary syndrome. The 14 small mammal species captured were composed of 10 rodents and four marsupials, the six most abundant species being Akodon serrensis, Oxymycterus judex, Akodon montensis, Akodon paranaensis, Oligoryzomys nigripes, and Thaptomys nigrita. These species displayed a similar pattern with increasing population sizes in fall/winter caused by recruitment and both, increase in reproductive activity and higher hantavirus prevalence in spring/summer. Specific associations between A. montensis/Jaborá Virus (JABV) and O. nigripes/Juquitiba-like Virus (JUQV-like) and spillover infections between A. paranaensis/JABV, A. serrensis/JABV, and A. paranaensis/JUQV-like were observed. Spillover infection in secondary hosts seems to play an important role in maintaining JABV and JUQV-like in the hantavirus sylvatic cycle mainly during periods of low prevalence in primary hosts. PMID:24935954

  17. Hantavirus Pulmonary Syndrome in Santa Cruz, Bolivia: Outbreak Investigation and Antibody Prevalence Study

    Science.gov (United States)

    Montgomery, Joel M.; Blair, Patrick J.; Carroll, Darin S.; Mills, James N.; Gianella, Alberto; Iihoshi, Naomi; Briggiler, Ana M.; Felices, Vidal; Salazar, Milagros; Olson, James G.; Glabman, Raisa A.; Bausch, Daniel G.

    2012-01-01

    We report the results of an investigation of a small outbreak of hantavirus pulmonary syndrome in 2002 in the Department of Santa Cruz, Bolivia, where the disease had not previously been reported. Two cases were initially reported. The first case was a physician infected with Laguna Negra virus during a weekend visit to his ranch. Four other persons living on the ranch were IgM antibody-positive, two of whom were symptomatic for mild hantavirus pulmonary syndrome. The second case was a migrant sugarcane worker. Although no sample remained to determine the specific infecting hantavirus, a virus 90% homologous with Río Mamoré virus was previously found in small-eared pygmy rice rats (Oligoryzomys microtis) trapped in the area. An antibody prevalence study conducted in the region as part of the outbreak investigation showed 45 (9.1%) of 494 persons to be IgG positive, illustrating that hantavirus infection is common in Santa Cruz Department. Precipitation in the months preceding the outbreak was particularly heavy in comparison to other years, suggesting a possible climatic or ecological influence on rodent populations and risk of hantavirus transmission to humans. Hantavirus infection appears to be common in the Santa Cruz Department, but more comprehensive surveillance and field studies are needed to fully understand the epidemiology and risk to humans. PMID:23094116

  18. Rickettsia bellii, Rickettsia amblyommii, and Laguna Negra hantavirus in an Indian reserve in the Brazilian Amazon

    OpenAIRE

    de Barros Lopes, Lívia; Guterres, Alexandro; Rozental, Tatiana; Carvalho de Oliveira, Renata; Mares-Guia, Maria Angélica; Fernandes, Jorlan; Figueredo, José Ferreira; Anschau, Inês; de Jesus, Sebastião; V Almeida, Ana Beatriz M; Cristina da Silva, Valéria; Gomes de Melo Via, Alba Valéria; Bonvicino, Cibele Rodrigues; D’Andrea, Paulo Sérgio; Barreira, Jairo Dias

    2014-01-01

    Background The purpose of this study was to identify the presence of rickettsia and hantavirus in wild rodents and arthropods in response to an outbreak of acute unidentified febrile illness among Indians in the Halataikwa Indian Reserve, northwest of the Mato Grosso state, in the Brazilian Amazon. Where previously surveillance data showed serologic evidence of rickettsia and hantavirus human infection. Methods The arthropods were collected from the healthy Indian population and by flagging v...

  19. Hantavirus Gn and Gc glycoproteins self-assemble into virus-like particles.

    Science.gov (United States)

    Acuña, Rodrigo; Cifuentes-Muñoz, Nicolás; Márquez, Chantal L; Bulling, Manuela; Klingström, Jonas; Mancini, Roberta; Lozach, Pierre-Yves; Tischler, Nicole D

    2014-02-01

    How hantaviruses assemble and exit infected cells remains largely unknown. Here, we show that the expression of Andes (ANDV) and Puumala (PUUV) hantavirus Gn and Gc envelope glycoproteins lead to their self-assembly into virus-like particles (VLPs) which were released to cell supernatants. The viral nucleoprotein was not required for particle formation. Further, a Gc endodomain deletion mutant did not abrogate VLP formation. The VLPs were pleomorphic, exposed protrusions and reacted with patient sera.

  20. New World hantaviruses activate IFNlambda production in type I IFN-deficient vero E6 cells.

    Directory of Open Access Journals (Sweden)

    Joseph Prescott

    Full Text Available Hantaviruses indigenous to the New World are the etiologic agents of hantavirus cardiopulmonary syndrome (HCPS. These viruses induce a strong interferon-stimulated gene (ISG response in human endothelial cells. African green monkey-derived Vero E6 cells are used to propagate hantaviruses as well as many other viruses. The utility of the Vero E6 cell line for virus production is thought to owe to their lack of genes encoding type I interferons (IFN, rendering them unable to mount an efficient innate immune response to virus infection. Interferon lambda, a more recently characterized type III IFN, is transcriptionally controlled much like the type I IFNs, and activates the innate immune system in a similar manner.We show that Vero E6 cells respond to hantavirus infection by secreting abundant IFNlambda. Three New World hantaviruses were similarly able to induce IFNlambda expression in this cell line. The IFNlambda contained within virus preparations generated with Vero E6 cells independently activates ISGs when used to infect several non-endothelial cell lines, whereas innate immune responses by endothelial cells are specifically due to viral infection. We show further that Sin Nombre virus replicates to high titer in human hepatoma cells (Huh7 without inducing ISGs.Herein we report that Vero E6 cells respond to viral infection with a highly active antiviral response, including secretion of abundant IFNlambda. This cytokine is biologically active, and when contained within viral preparations and presented to human epithelioid cell lines, results in the robust activation of innate immune responses. We also show that both Huh7 and A549 cell lines do not respond to hantavirus infection, confirming that the cytoplasmic RNA helicase pathways possessed by these cells are not involved in hantavirus recognition. We demonstrate that Vero E6 actively respond to virus infection and inhibiting IFNlambda production in these cells might increase their utility

  1. Hantavirus-induced disruption of the endothelial barrier: Neutrophils are on the payroll

    Directory of Open Access Journals (Sweden)

    Günther eSchönrich

    2015-03-01

    Full Text Available Viral hemorrhagic fever caused by hantaviruses is an emerging infectious disease for which suita-ble treatments are not available. In order to improve this situation a better understanding of han-taviral pathogenesis is urgently required. Hantaviruses infect endothelial cell layers in vitro with-out causing any cytopathogenic effect and without increasing permeability. This implies that the mechanisms underlying vascular hyperpermeability in hantavirus-associated disease are more complex and that immune mechanisms play an important role. In this review we highlight the lat-est developments in hantavirus-induced immunopathogenesis. A possible contribution of neutro-phils has been neglected so far. For this reason, we place special emphasis on the pathogenic role of neutrophils in disrupting the endothelial barrier.

  2. Hantavirus-induced disruption of the endothelial barrier: neutrophils are on the payroll.

    Science.gov (United States)

    Schönrich, Günther; Krüger, Detlev H; Raftery, Martin J

    2015-01-01

    Viral hemorrhagic fever caused by hantaviruses is an emerging infectious disease for which suitable treatments are not available. In order to improve this situation a better understanding of hantaviral pathogenesis is urgently required. Hantaviruses infect endothelial cell layers in vitro without causing any cytopathogenic effect and without increasing permeability. This implies that the mechanisms underlying vascular hyperpermeability in hantavirus-associated disease are more complex and that immune mechanisms play an important role. In this review we highlight the latest developments in hantavirus-induced immunopathogenesis. A possible contribution of neutrophils has been neglected so far. For this reason, we place special emphasis on the pathogenic role of neutrophils in disrupting the endothelial barrier.

  3. Hantaviruses in the Americas and Their Role as Emerging Pathogens

    Directory of Open Access Journals (Sweden)

    Fernando Torres-Pérez

    2010-11-01

    Full Text Available The continued emergence and re-emergence of pathogens represent an ongoing, sometimes major, threat to populations. Hantaviruses (family Bunyaviridae and their associated human diseases were considered to be confined to Eurasia, but the occurrence of an outbreak in 1993–94 in the southwestern United States led to a great increase in their study among virologists worldwide. Well over 40 hantaviral genotypes have been described, the large majority since 1993, and nearly half of them pathogenic for humans. Hantaviruses cause persistent infections in their reservoir hosts, and in the Americas, human disease is manifest as a cardiopulmonary compromise, hantavirus cardiopulmonary syndrome (HCPS, with case-fatality ratios, for the most common viral serotypes, between 30% and 40%. Habitat disturbance and larger-scale ecological disturbances, perhaps including climate change, are among the factors that may have increased the human caseload of HCPS between 1993 and the present. We consider here the features that influence the structure of host population dynamics that may lead to viral outbreaks, as well as the macromolecular determinants of hantaviruses that have been regarded as having potential contribution to pathogenicity.

  4. Novel camelid antibody fragments targeting recombinant nucleoprotein of Araucaria hantavirus: a prototype for an early diagnosis of Hantavirus Pulmonary Syndrome.

    Directory of Open Access Journals (Sweden)

    Soraya S Pereira

    Full Text Available In addition to conventional antibodies, camelids produce immunoglobulins G composed exclusively of heavy chains in which the antigen binding site is formed only by single domains called VHH. Their particular characteristics make VHHs interesting tools for drug-delivery, passive immunotherapy and high-throughput diagnosis. Hantaviruses are rodent-borne viruses of the Bunyaviridae family. Two clinical forms of the infection are known. Hemorrhagic Fever with Renal Syndrome (HFRS is present in the Old World, while Hantavirus Pulmonary Syndrome (HPS is found on the American continent. There is no specific treatment for HPS and its diagnosis is carried out by molecular or serological techniques, using mainly monoclonal antibodies or hantavirus nucleoprotein (N to detect IgM and IgG in patient serum. This study proposes the use of camelid VHHs to develop alternative methods for diagnosing and confirming HPS. Phage display technology was employed to obtain VHHs. After immunizing one Lama glama against the recombinant N protein (prNΔ₈₅ of a Brazilian hantavirus strain, VHH regions were isolated to construct an immune library. VHHs were displayed fused to the M13KO7 phage coat protein III and the selection steps were performed on immobilized prNΔ₈₅. After selection, eighty clones recognized specifically the N protein. These were sequenced, grouped based mainly on the CDRs, and five clones were analyzed by western blot (WB, surface plasmon resonance (SPR device, and ELISA. Besides the ability to recognize prNΔ85 by WB, all selected clones showed affinity constants in the nanomolar range. Additionaly, the clone KC329705 is able to detect prNΔ₈₅ in solution, as well as the native viral antigen. Findings support the hypothesis that selected VHHs could be a powerful tool in the development of rapid and accurate HPS diagnostic assays, which are essential to provide supportive care to patients and reduce the high mortality rate associated with

  5. Hantavirus strains in East Africa related to Western African hantaviruses

    Czech Academy of Sciences Publication Activity Database

    Těšíková, Jana; Bryjová, Anna; Bryja, Josef; Lavrenchenko, L. A.; Goüy de Bellocq, Joëlle

    2017-01-01

    Roč. 17, č. 4 (2017), s. 278-280 ISSN 1530-3667 R&D Projects: GA ČR GCP502/11/J070 Institutional support: RVO:68081766 Keywords : bats * East Africa * hantavirus * phylogeny * rodents Subject RIV: EE - Microbiology, Virology OBOR OECD: Infectious Diseases Impact factor: 2.045, year: 2016

  6. Large outbreak of Cryptosporidium hominis infection transmitted through the public water supply, Sweden.

    Science.gov (United States)

    Widerström, Micael; Schönning, Caroline; Lilja, Mikael; Lebbad, Marianne; Ljung, Thomas; Allestam, Görel; Ferm, Martin; Björkholm, Britta; Hansen, Anette; Hiltula, Jari; Långmark, Jonas; Löfdahl, Margareta; Omberg, Maria; Reuterwall, Christina; Samuelsson, Eva; Widgren, Katarina; Wallensten, Anders; Lindh, Johan

    2014-04-01

    In November 2010, ≈27,000 (≈45%) inhabitants of Östersund, Sweden, were affected by a waterborne outbreak of cryptosporidiosis. The outbreak was characterized by a rapid onset and high attack rate, especially among young and middle-aged persons. Young age, number of infected family members, amount of water consumed daily, and gluten intolerance were identified as risk factors for acquiring cryptosporidiosis. Also, chronic intestinal disease and young age were significantly associated with prolonged diarrhea. Identification of Cryptosporidium hominis subtype IbA10G2 in human and environmental samples and consistently low numbers of oocysts in drinking water confirmed insufficient reduction of parasites by the municipal water treatment plant. The current outbreak shows that use of inadequate microbial barriers at water treatment plants can have serious consequences for public health. This risk can be minimized by optimizing control of raw water quality and employing multiple barriers that remove or inactivate all groups of pathogens.

  7. Ecology of rodent-associated hantaviruses in the Southern Cone of South America: Argentina, Chile, Paraguay, and Uruguay.

    Science.gov (United States)

    Palma, R Eduardo; Polop, Jaime J; Owen, Robert D; Mills, James N

    2012-04-01

    Thirteen hantavirus genotypes, associated with at least 12 sigmodontine reservoir rodents, have been recognized in the four countries that represent the Southern Cone of South America. Host-virus relationships are not as well defined as in North America; several Southern Cone hantaviruses appear to share a common host and some viruses do not occur throughout the range of their host. Although hantavirus-host relationships in the Southern Cone are less strictly concordant with the single-host-single-virus pattern reported elsewhere, recent studies suggest that much of the ambiguity may result from an incomplete understanding of host and hantavirus systematics. Although some Southern Cone host species are habitat generalists, some sympatric species are habitat specialists, helping to explain how some strict host-virus pairings may be maintained. In some cases, host population densities were higher in peridomestic habitats and prevalence of hantavirus infection was higher in host populations in peridomestic habitats. Seasonal and multiyear patterns in climate and human disturbance affect host population densities, prevalence of infection, and disease risk to humans. Unusually high hantavirus antibody prevalence in indigenous human populations may be associated with frequent and close contact with host rodents. Ongoing studies are improving our understanding of hantavirus-host ecology and providing tools that may predict human risk.

  8. Treatment of Hantavirus Pulmonary Syndrome

    Science.gov (United States)

    2007-10-14

    femoral artery and vein. The bed is versity of New Mexico. . Antiviral therapy Ribavirin was tested for efficacy in HFRS patients in China nd shown to...Weis- senbacher, M.C., 1996. Hantavirus pulmonary syndrome in Argentina. Possibility of person to person transmission. Medicina (B. Aires) 56, 709–711

  9. An outbreak of Salmonella Typhimurium infections in Denmark, Norway and Sweden, 2008.

    Science.gov (United States)

    Bruun, T; Sørensen, G; Forshell, L P; Jensen, T; Nygard, K; Kapperud, G; Lindstedt, B A; Berglund, T; Wingstrand, A; Petersen, R F; Müller, L; Kjelsø, C; Ivarsson, S; Hjertqvist, M; Löfdahl, S; Ethelberg, S

    2009-03-12

    In November-December 2008, Norway and Denmark independently identified outbreaks of Salmonella Typhimurium infections characterised in the multiple-locus variable number of tandem repeats analysis (MLVA) by a distinct profile. Outbreak investigations were initiated independently in the two countries. In Denmark, a total of 37 cases were identified, and multiple findings of the outbreak strain in pork and pigs within the same supply chain led to the identification of pork in various forms as the source. In Norway, ten cases were identified, and the outbreak investigation quickly indicated meat bought in Sweden as the probable source and the Swedish authorities were alerted. Investigations in Sweden identified four human cases and two isolates from minced meat with the distinct profile. Subsequent trace-back of the meat showed that it most likely originated from Denmark. Through international alert from Norway on 19 December, it became clear that the Danish and Norwegian outbreak strains were identical and, later on, that the source of the outbreaks in all three countries could be traced back to Danish pork. MLVA was instrumental in linking the outbreaks in the different countries and tracing the source. This outbreak illustrates that good international communication channels, early alerting mechanisms, inter-sectoral collaboration between public health and food safety authorities and harmonised molecular typing tools are important for effective identification and management of cross-border outbreaks. Differences in legal requirements for food safety in neighbouring countries may be a challenge in terms of communication with consumers in areas where cross-border shopping is common.

  10. [Hantavirus pulmonary syndrome (Rio Mamore virus) in the Peruvian Amazon region].

    Science.gov (United States)

    Casapía, Martín; Mamani, Enrique; García, María P; Miraval, María L; Valencia, Pedro; Quino, Alberto H; Alvarez, Carlos; Donaires, Luis F

    2012-01-01

    Hantavirus infection is a viral zoonotic infection borne by rodents which most letal form clinical is the Hantavirus Pulmonary Syndrome (SPH, Spanish abbreviation). The Mamore River variant originates in South America and was found in rodents without any association to human diseases. Two cases of SPH were identified in the Peruvian Amazon region in November 2011. In both cases, a molecular diagnostic testing was conducted by the Instituto Nacional de Salud from Peru. A phylogenetic analysis of a viral genome fragment and a histopathological evaluation were conducted. Both patients developed adult respiratory distress syndrome and refractory shock. A patient died and another one recovered 12 days later.

  11. Inhibition of the Hantavirus Fusion Process by Predicted Domain III and Stem Peptides from Glycoprotein Gc.

    Science.gov (United States)

    Barriga, Gonzalo P; Villalón-Letelier, Fernando; Márquez, Chantal L; Bignon, Eduardo A; Acuña, Rodrigo; Ross, Breyan H; Monasterio, Octavio; Mardones, Gonzalo A; Vidal, Simon E; Tischler, Nicole D

    2016-07-01

    Hantaviruses can cause hantavirus pulmonary syndrome or hemorrhagic fever with renal syndrome in humans. To enter cells, hantaviruses fuse their envelope membrane with host cell membranes. Previously, we have shown that the Gc envelope glycoprotein is the viral fusion protein sharing characteristics with class II fusion proteins. The ectodomain of class II fusion proteins is composed of three domains connected by a stem region to a transmembrane anchor in the viral envelope. These fusion proteins can be inhibited through exogenous fusion protein fragments spanning domain III (DIII) and the stem region. Such fragments are thought to interact with the core of the fusion protein trimer during the transition from its pre-fusion to its post-fusion conformation. Based on our previous homology model structure for Gc from Andes hantavirus (ANDV), here we predicted and generated recombinant DIII and stem peptides to test whether these fragments inhibit hantavirus membrane fusion and cell entry. Recombinant ANDV DIII was soluble, presented disulfide bridges and beta-sheet secondary structure, supporting the in silico model. Using DIII and the C-terminal part of the stem region, the infection of cells by ANDV was blocked up to 60% when fusion of ANDV occurred within the endosomal route, and up to 95% when fusion occurred with the plasma membrane. Furthermore, the fragments impaired ANDV glycoprotein-mediated cell-cell fusion, and cross-inhibited the fusion mediated by the glycoproteins from Puumala virus (PUUV). The Gc fragments interfered in ANDV cell entry by preventing membrane hemifusion and pore formation, retaining Gc in a non-resistant homotrimer stage, as described for DIII and stem peptide inhibitors of class II fusion proteins. Collectively, our results demonstrate that hantavirus Gc shares not only structural, but also mechanistic similarity with class II viral fusion proteins, and will hopefully help in developing novel therapeutic strategies against hantaviruses.

  12. Indirect immunofluorescence assay for the simultaneous detection of antibodies against clinically important old and new world hantaviruses.

    Directory of Open Access Journals (Sweden)

    Sabine Lederer

    Full Text Available In order to detect serum antibodies against clinically important Old and New World hantaviruses simultaneously, multiparametric indirect immunofluorescence assays (IFAs based on biochip mosaics were developed. Each of the mosaic substrates consisted of cells infected with one of the virus types Hantaan (HTNV, Puumala (PUUV, Seoul (SEOV, Saaremaa (SAAV, Dobrava (DOBV, Sin Nombre (SNV or Andes (ANDV. For assay evaluation, serum IgG and IgM antibodies were analyzed using 184 laboratory-confirmed hantavirus-positive sera collected at six diagnostic centers from patients actively or previously infected with the following hantavirus serotypes: PUUV (Finland, n=97; SEOV (China, n=5; DOBV (Romania, n=7; SNV (Canada, n=23; ANDV (Argentina and Chile, n=52. The control panel comprised 89 sera from healthy blood donors. According to the reference tests, all 184 patient samples were seropositive for hantavirus-specific IgG (n=177; 96% and/or IgM (n=131; 72%, while all control samples were tested negative. In the multiparametric IFA applied in this study, 183 (99% of the patient sera were IgG and 131 (71% IgM positive (accordance with the reference tests: IgG, 96%; IgM, 93%. Overall IFA sensitivity for combined IgG and IgM analysis amounted to 100% for all serotypes, except for SNV (96%. Of the 89 control sera, 2 (2% showed IgG reactivity against the HTNV substrate, but not against any other hantavirus. Due to the high cross-reactivity of hantaviral nucleocapsid proteins, endpoint titrations were conducted, allowing serotype determination in >90% of PUUV- and ANDV-infected patients. Thus, multiparametric IFA enables highly sensitive and specific serological diagnosis of hantavirus infections and can be used to differentiate PUUV and ANDV infection from infections with Murinae-borne hantaviruses (e.g. DOBV and SEOV.

  13. Expression of a hantavirus N protein and its efficacy as antigen in immune assays

    Directory of Open Access Journals (Sweden)

    L.T.M. Figueiredo

    2008-07-01

    Full Text Available Hantavirus cardiopulmonary syndrome (HCPS has been recognized as an important public heath problem. Five hantaviruses associated with HCPS are currently known in Brazil: Juquitiba, Araraquara, Laguna Negra-like, Castelo dos Sonhos, and Anajatuba viruses. The laboratory diagnosis of HCPS is routinely carried out by the detection of anti-hantavirus IgM and/or IgG antibodies. The present study describes the expression of the N protein of a hantavirus detected in the blood sample of an HCPS patient. The entire S segment of the virus was amplified and found to be 1858 nucleotides long, with an open reading frame of 1287 nucleotides that encodes a protein of 429 amino acids. The nucleotide sequence described here showed a high identity with the N protein gene of Araraquara virus. The entire N protein was expressed using the vector pET200D and the Escherichia coli BL21 strain. The expression of the recombinant protein was confirmed by the detection of a 52-kDa protein by Western blot using a pool of human sera obtained from HCPS patients, and by specific IgG detection in five serum samples of HCPS patients tested by ELISA. These results suggest that the recombinant N protein could be used as an antigen for the serological screening of hantavirus infection.

  14. Seroprevalence of hantavirus and Yersinia pestis antibodies in professionals from the Plague Control Program

    Directory of Open Access Journals (Sweden)

    Erika de Cassia Vieira da Costa

    2013-07-01

    Full Text Available Introduction Professionals who handle rodents in the field and in the laboratory are at risk of infection by the microorganisms harbored by these animals. Methods Serum samples from professionals involved in rodent and Yersinia pestis handling in field or laboratory work were analyzed to determine hantavirus and plague seroprevalence and to establish a relationship between these activities and reports of illnesses. Results Two individuals had antibodies against hantavirus, and two harbored antibodies against the plague; none of the individuals had experienced an illness related to their duties. Conclusions These results confirm the risks of hantavirus- and plague-related field and laboratory activities and the importance of protective measures for such work.

  15. Hantavirus Pulmonary Syndrome

    Science.gov (United States)

    ... Infectious Diseases Division of High-Consequence Pathogens and Pathology How is HPS diagnosed? Diagnosing HPS in an individual who has only been infected for a few days is difficult, because early symptoms such as fever, muscle aches, and fatigue are easily confused with influenza. ...

  16. Andes hantavirus variant in rodents, southern Amazon Basin, Peru.

    Science.gov (United States)

    Razuri, Hugo; Tokarz, Rafal; Ghersi, Bruno M; Salmon-Mulanovich, Gabriela; Guezala, M Claudia; Albujar, Christian; Mendoza, A Patricia; Tinoco, Yeny O; Cruz, Christopher; Silva, Maria; Vasquez, Alicia; Pacheco, Víctor; Ströher, Ute; Guerrero, Lisa Wiggleton; Cannon, Deborah; Nichol, Stuart T; Hirschberg, David L; Lipkin, W Ian; Bausch, Daniel G; Montgomery, Joel M

    2014-02-01

    We investigated hantaviruses in rodents in the southern Amazon Basin of Peru and identified an Andes virus variant from Neacomys spinosus mice. This finding extends the known range of this virus in South America and the range of recognized hantaviruses in Peru. Further studies of the epizoology of hantaviruses in this region are warranted.

  17. Andes Hantavirus Variant in Rodents, Southern Amazon Basin, Peru

    OpenAIRE

    Razuri, Hugo; Tokarz, Rafal; Ghersi, Bruno M.; Salmon-Mulanovich, Gabriela; Guezala, M. Claudia; Albujar, Christian; Mendoza, A. Patricia; Tinoco, Yeny O.; Cruz, Christopher; Silva, Maria; Vasquez, Alicia; Pacheco, Víctor; Ströher, Ute; Guerrero, Lisa Wiggleton; Cannon, Deborah

    2014-01-01

    We investigated hantaviruses in rodents in the southern Amazon Basin of Peru and identified an Andes virus variant from Neacomys spinosus mice. This finding extends the known range of this virus in South America and the range of recognized hantaviruses in Peru. Further studies of the epizoology of hantaviruses in this region are warranted.

  18. Rodent Species Distribution and Hantavirus Seroprevalence in Residential and Forested areas of Sarawak, Malaysia.

    Science.gov (United States)

    Hamdan, Nur Elfieyra Syazana; Ng, Yee Ling; Lee, Wei Bin; Tan, Cheng Siang; Khan, Faisal Ali Anwarali; Chong, Yee Ling

    2017-01-01

    Rodents belong to the order Rodentia, which consists of three families in Borneo (i.e., Muridae, Sciuridae and Hystricidae). These include rats, mice, squirrels, and porcupines. They are widespread throughout the world and considered pests that harm humans and livestock. Some rodent species are natural reservoirs of hantaviruses (Family: Bunyaviridae) that can cause zoonotic diseases in humans. Although hantavirus seropositive human sera were reported in Peninsular Malaysia in the early 1980s, information on their infection in rodent species in Malaysia is still lacking. The rodent populations in residential and forested areas in Sarawak were sampled. A total of 108 individuals from 15 species of rodents were collected in residential ( n = 44) and forested ( n = 64) areas. The species diversity of rodents in forested areas was significantly higher (H = 2.2342) compared to rodents in residential areas (H = 0.64715) ( p Sarawak, East Malaysia. The results suggested that hantavirus was not circulating in the studied rodent populations in Sarawak, or it was otherwise at a low prevalence that is below the detection threshold. It is important to remain vigilant because of the zoonotic potential of this virus and its severe disease outcome. Further studies, such as molecular detection of viral genetic materials, are needed to fully assess the risk of hantavirus infection in rodents and humans in this region of Malaysia.

  19. T Cells and Pathogenesis of Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever with Renal Syndrome

    Directory of Open Access Journals (Sweden)

    Francis A. Ennis

    2011-07-01

    Full Text Available We previously hypothesized that increased capillary permeability observed in both hantavirus cardiopulmonary syndrome (HCPS and hemorrhagic fever with renal syndrome (HFRS may be caused by hantavirus-specific cytotoxic T cells attacking endothelial cells presenting viral antigens on their surface based on clinical observations and in vitro experiments. In HCPS, hantavirus-specific T cell responses positively correlated with disease severity. In HFRS, in one report, contrary to HCPS, T cell responses negatively correlated with disease severity, but in another report the number of regulatory T cells, which are thought to suppress T cell responses, negatively correlated with disease severity. In rat experiments, in which hantavirus causes persistent infection, depletion of regulatory T cells helped infected rats clear virus without inducing immunopathology. These seemingly contradictory findings may suggest delicate balance in T cell responses between protection and immunopathogenesis. Both too strong and too weak T cell responses may lead to severe disease. It is important to clarify the role of T cells in these diseases for better treatment (whether to suppress T cell functions and protection (vaccine design which may need to take into account viral factors and the influence of HLA on T cell responses.

  20. Detection of Brazilian hantavirus by reverse transcription polymerase chain reaction amplification of N gene in patients with hantavirus cardiopulmonary syndrome

    OpenAIRE

    Marcos Lázaro Moreli; Ricardo Luiz Moro de Sousa; Luiz Tadeu Moraes Figueiredo

    2004-01-01

    We report a nested reverse transcription-polymerase chain reaction (RT-PCR) assay for hantavirus using primers selected to match high homology regions of hantavirus genomes detected from the whole blood of hantavirus cardiopulmonary syndrome (HCPS) patients from Brazil, also including the N gene nucleotide sequence of Araraquara virus. Hantavirus genomes were detected in eight out of nine blood samples from the HCPS patients by RT-PCR (88.9% positivity) and in all 9 blood samples (100% positi...

  1. Hantavirus

    Science.gov (United States)

    ... heavy infestation of rodents, call a pest control company. They have special cleanup equipment and methods. Alternative ... M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health ...

  2. Detecting the Norovirus Season in Sweden Using Search Engine Data – Meeting the Needs of Hospital Infection Control Teams

    Science.gov (United States)

    Edelstein, Michael; Wallensten, Anders; Zetterqvist, Inga; Hulth, Anette

    2014-01-01

    Norovirus outbreaks severely disrupt healthcare systems. We evaluated whether Websök, an internet-based surveillance system using search engine data, improved norovirus surveillance and response in Sweden. We compared Websök users' characteristics with the general population, cross-correlated weekly Websök searches with laboratory notifications between 2006 and 2013, compared the time Websök and laboratory data crossed the epidemic threshold and surveyed infection control teams about their perception and use of Websök. Users of Websök were not representative of the general population. Websök correlated with laboratory data (b = 0.88-0.89) and gave an earlier signal to the onset of the norovirus season compared with laboratory-based surveillance. 17/21 (81%) infection control teams answered the survey, of which 11 (65%) believed Websök could help with infection control plans. Websök is a low-resource, easily replicable system that detects the norovirus season as reliably as laboratory data, but earlier. Using Websök in routine surveillance can help infection control teams prepare for the yearly norovirus season. PMID:24955857

  3. Detecting the norovirus season in Sweden using search engine data--meeting the needs of hospital infection control teams.

    Science.gov (United States)

    Edelstein, Michael; Wallensten, Anders; Zetterqvist, Inga; Hulth, Anette

    2014-01-01

    Norovirus outbreaks severely disrupt healthcare systems. We evaluated whether Websök, an internet-based surveillance system using search engine data, improved norovirus surveillance and response in Sweden. We compared Websök users' characteristics with the general population, cross-correlated weekly Websök searches with laboratory notifications between 2006 and 2013, compared the time Websök and laboratory data crossed the epidemic threshold and surveyed infection control teams about their perception and use of Websök. Users of Websök were not representative of the general population. Websök correlated with laboratory data (b = 0.88-0.89) and gave an earlier signal to the onset of the norovirus season compared with laboratory-based surveillance. 17/21 (81%) infection control teams answered the survey, of which 11 (65%) believed Websök could help with infection control plans. Websök is a low-resource, easily replicable system that detects the norovirus season as reliably as laboratory data, but earlier. Using Websök in routine surveillance can help infection control teams prepare for the yearly norovirus season.

  4. Clinical characterization of two severe cases of hemorrhagic fever with renal syndrome (HFRS caused by hantaviruses Puumala and Dobrava-Belgrade genotype Sochi

    Directory of Open Access Journals (Sweden)

    Ellen Krautkrämer

    2016-11-01

    Full Text Available Abstract Background Hantavirus disease belongs to the emerging infections. The clinical picture and severity of infections differ between hantavirus species and may even vary between hantavirus genotypes. The mechanisms that lead to the broad variance of severity in infected patients are not completely understood. Host- and virus-specific factors are considered. Case presentation We analyzed severe cases of hantavirus disease in two young women. The first case was caused by Puumala virus (PUUV infection in Germany; the second case describes the infection with Dobrava-Belgrade virus (DOBV in Russia. Symptoms, laboratory parameters and cytokine levels were analyzed and compared between the two patients. Serological and sequence analysis revealed that PUUV was the infecting agent for the German patient and the infection of the Russian patient was caused by Dobrava-Belgrade virus genotype Sochi (DOBV-Sochi. The symptoms in the initial phase of the diseases did not differ noticeably between both patients. However, deterioration of laboratory parameter values was prolonged and stronger in DOBV-Sochi than in PUUV infection. Circulating endothelial progenitor cells (cEPCs, known to be responsible for endothelial repair, were mobilized in both infections. Striking differences were observed in the temporal course and level of cytokine upregulation. Levels of angiopoietin-2 (Ang-2, vascular endothelial growth factor (VEGF, and stromal derived factor-1 (SDF-1α were increased in both infections; but, sustained and more pronounced elevation was observed in DOBV-Sochi infection. Conclusions Severe hantavirus disease caused by different hantavirus species did not differ in the general symptoms and clinical characteristics. However, we observed a prolonged clinical course and a late and enhanced mobilization of cytokines in DOBV-Sochi infection. The differences in cytokine deregulation may contribute to the observed variation in the clinical course.

  5. Old World hantaviruses in rodents in New Orleans, Louisiana.

    Science.gov (United States)

    Cross, Robert W; Waffa, Bradley; Freeman, Ashley; Riegel, Claudia; Moses, Lina M; Bennett, Andrew; Safronetz, David; Fischer, Elizabeth R; Feldmann, Heinz; Voss, Thomas G; Bausch, Daniel G

    2014-05-01

    Seoul virus, an Old World hantavirus, is maintained in brown rats and causes a mild form of hemorrhagic fever with renal syndrome (HFRS) in humans. We captured rodents in New Orleans, Louisiana and tested them for the presence of Old World hantaviruses by reverse transcription polymerase chain reaction (RT-PCR) with sequencing, cell culture, and electron microscopy; 6 (3.4%) of 178 rodents captured--all brown rats--were positive for a Seoul virus variant previously coined Tchoupitoulas virus, which was noted in rodents in New Orleans in the 1980s. The finding of Tchoupitoulas virus in New Orleans over 25 years since its first discovery suggests stable endemicity in the city. Although the degree to which this virus causes human infection and disease remains unknown, repeated demonstration of Seoul virus in rodent populations, recent cases of laboratory-confirmed HFRS in some US cities, and a possible link with hypertensive renal disease warrant additional investigation in both rodents and humans.

  6. Rickettsia bellii, Rickettsia amblyommii, and Laguna Negra hantavirus in an Indian reserve in the Brazilian Amazon.

    Science.gov (United States)

    de Barros Lopes, Lívia; Guterres, Alexandro; Rozental, Tatiana; Carvalho de Oliveira, Renata; Mares-Guia, Maria Angélica; Fernandes, Jorlan; Figueredo, José Ferreira; Anschau, Inês; de Jesus, Sebastião; V Almeida, Ana Beatriz M; Cristina da Silva, Valéria; Gomes de Melo Via, Alba Valéria; Bonvicino, Cibele Rodrigues; D'Andrea, Paulo Sérgio; Barreira, Jairo Dias; Sampaio de Lemos, Elba Regina

    2014-04-17

    The purpose of this study was to identify the presence of rickettsia and hantavirus in wild rodents and arthropods in response to an outbreak of acute unidentified febrile illness among Indians in the Halataikwa Indian Reserve, northwest of the Mato Grosso state, in the Brazilian Amazon. Where previously surveillance data showed serologic evidence of rickettsia and hantavirus human infection. The arthropods were collected from the healthy Indian population and by flagging vegetation in grassland or woodland along the peridomestic environment of the Indian reserve. Wild rodents were live-trapped in an area bordering the reserve limits, due the impossibility of capturing wild animals in the Indian reserve. The wild rodents were identified based on external and cranial morphology and karyotype. DNA was extracted from spleen or liver samples of rodents and from invertebrate (tick and louse) pools, and the molecular characterization of the rickettsia was through PCR and DNA sequencing of fragments of two rickettsial genes (gltA and ompA). In relation to hantavirus, rodent serum samples were serologically screened by IgG ELISA using the Araraquara-N antigen and total RNA was extracted from lung samples of IgG-positive rodents. The amplification of the complete S segment was performed. A total of 153 wild rodents, 121 louse, and 36 tick specimens were collected in 2010. Laguna Negra hantavirus was identified in Calomys callidus rodents and Rickettsia bellii, Rickettsia amblyommii were identified in Amblyomma cajennense ticks. Zoonotic diseases such as HCPS and spotted fever rickettsiosis are a public health threat and should be considered in outbreaks and acute febrile illnesses among Indian populations. The presence of the genome of rickettsias and hantavirus in animals in this Indian reserve reinforces the need to include these infectious agents in outbreak investigations of febrile cases in Indian populations.

  7. KARAKTERISTIK LINGKUNGAN DAN ASPEK SOSIAL DEMOGRAFI DALAM KAITANNYA DENGAN PENYAKIT INFEKSI HANTAVIRUS DI WILAYAH PELABUHAN TANJUNG PRIOK DAN SUNDA KELAPA, JAKARTA UTARA

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    Kasnodihardjo Kasnodihardjo

    2012-11-01

    Full Text Available Epidemiological study on hantavirus infection diseases in the area of Tanjung Priok and Sunda Kelapa Harbours has been conducted in the year of 1997; Considering a harbour may become a very potential port d'antre of diseases between islands, regions and countries. Hantavirus infection is well known as haemorrhagic fever with renal syndrome (HFRS, cause by some species of genus Hantavirus and transmitted to human by air droplet contaminated by urine, saliva or faeces of infected rodents. This is toreport a part of the study which is stress on sociocultural aspects, especially character of demography and community perceptions to hantavirus infection diseases. The data were collected by interviewing using questionaires and field observations. Sample population were household (HH while family members above 13 year of age including head of HH (Kepala Rumah Tangga were chosen as individual respondents and become analitical units. In total the number of samples were 113 HH, consisting 58 HH in Kelurahan Koja and 55 HH in Kelurahan Ancol. The number of individual respondents were 410 people. The results showed that most of respondents work as a labor in the harbours. In general they have low level formal education, mostly only elementary school graduated. The relatively low of their formal education they have might influence their wrong perceptions to any disease. The wrong community perceptions in the two areas mistaken hantavirus infection diseases with typhoid diseases.

  8. Evaluation of Copper Supplementation to Control Haemonchus contortus Infections of Sheep in Sweden

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    Rydzik A

    2004-09-01

    Full Text Available A pen study was conducted to assess the effect of providing daily copper mineral supplement, or copper wire particle (COWP capsules, on established or incoming mixed nematode infections in young sheep. For lambs with established (6 week old infections, COWP resulted in 97% and 56% reduction of the adult and early L4 stages of H. contortus, respectively, compared with controls (p Teladorsagia circumcincta infections in the COWP lambs compared with controls (p H. contortus infections, but lack of parasites during the grazing season prevented an adequate assessment from being made. These results indicate that there is little, if any, benefit from a parasite control standpoint in recommending copper therapy, specifically to control parasites in Swedish sheep flocks.

  9. Geographical distribution of salmonella infected pig, cattle and sheep herds in Sweden 1993-2010

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    Skog Lars

    2011-10-01

    Full Text Available Abstract Background The Swedish salmonella control programme covers the entire production chain, from feed to food. All salmonella serotypes are notifiable. On average, less than 20 cases of salmonella in food-producing animals are reported every year. In some situations, the cases would be expected to cluster geographically. The aim of this study was to illustrate the geographic distribution of the salmonella cases detected in pigs, cattle and sheep. Methods Data on all herds with pigs, cattle and sheep found to be infected with salmonella during the time period from 1993 to 2010 were obtained from the Swedish Board of Agriculture. Using the ArcGIS software, various maps were produced of infected herds, stratified on animal species as well as salmonella serotype. Based on ocular inspection of all maps, some were collapsed and some used separately. Data were also examined for temporal trends. Results No geographical clustering was observed for ovine or porcine cases. Cattle herds infected with Salmonella Dublin were mainly located in the southeast region and cattle herds infected with Salmonella Typhimurium in the most southern part of the country. Some seasonal variation was seen in cattle, but available data was not sufficient for further analyses. Conclusions Analyses of data on salmonella infected herds revealed some spatial and temporal patterns for salmonella in cattle. However, despite using 18 years' of data, the number of infected herds was too low for any useful statistical analyses.

  10. Rhinitis, Asthma and Respiratory Infections among Adults in Relation to the Home Environment in Multi-Family Buildings in Sweden

    Science.gov (United States)

    Wang, Juan; Engvall, Karin; Smedje, Greta; Norbäck, Dan

    2014-01-01

    Risk factors for rhinitis, asthma and respiratory infections in the home environment were studied by a questionnaire survey. Totally 5775 occupants (≥18 years old) from a stratified random sample of multi-family buildings in Sweden participated (46%). 51.0% had rhinitis in the last 3 months (current rhinitis); 11.5% doctor diagnosed asthma; 46.4% respiratory infections in the last 3 months and 11.9% antibiotic medication for respiratory infections in the last 12 months. Associations between home environment and health were analyzed by multiple logistic regression, controlling for gender, age and smoking and mutual adjustment. Buildings constructed during 1960–1975 were risk factors for day time breathlessness (OR = 1.53, 95%CI 1.03–2.29). And those constructed during 1976–1985 had more current rhinitis (OR = 1.43, 95%CI 1.12–1.84) and respiratory infections (OR = 1.46, 95%CI 1.21–1.78). Cities with higher population density had more current rhinitis (p = 0.008) and respiratory infections (pBuilding dampness was a risk factor for wheeze (OR = 1.42, 95%CI 1.08–1.86) and day time breathlessness (OR = 1.57, 95%CI 1.09–2.27). Building dampness was a risk factor for health among those below 66 years old. Odor at home was a risk factor for doctor diagnosed asthma (OR = 1.49, 95%CI 1.08–2.06) and current asthma (OR = 1.52, 95%CI 1.03–2.24). Environmental tobacco smoke (ETS) was a risk factor for current asthma (OR = 1.53, 95%CI 1.09–2.16). Window pane condensation was a risk factor for antibiotic medication for respiratory infections (OR = 1.41, 95%CI 1.10–1.82). In conclusion, rhinitis, asthma and respiratory infections were related to a number of factors in the home environment. Certain building years (1961–1985), building dampness, window pane condensation and odor in the dwelling may be risk factors. PMID:25136984

  11. Tula and Puumala hantavirus NSs ORFs are functional and the products inhibit activation of the interferon-beta promoter.

    Science.gov (United States)

    Jääskeläinen, Kirsi M; Kaukinen, Pasi; Minskaya, Ekaterina S; Plyusnina, Angelina; Vapalahti, Olli; Elliott, Richard M; Weber, Friedemann; Vaheri, Antti; Plyusnin, Alexander

    2007-10-01

    The S RNA genome segment of hantaviruses carried by Arvicolinae and Sigmodontinae rodents encodes the nucleocapsid (N) protein and has an overlapping (+1) open reading frame (ORF) for a putative nonstructural protein (NSs). The aim of this study was to determine whether the ORF is functional. A protein corresponding to the predicted size of Tula virus (TULV) NSs was detected using coupled in vitro transcription and translation from a cloned S segment cDNA, and a protein corresponding to the predicted size of Puumala virus (PUUV) NSs was detected in infected cells by Western blotting with an anti-peptide serum. The activities of the interferon beta (IFN-beta) promoter, and nuclear factor kappa B (NF-kappaB)- and interferon regulatory factor-3 (IRF-3) responsive promoters, were inhibited in COS-7 cells transiently expressing TULV or PUUV NSs. Also IFN-beta mRNA levels in IFN-competent MRC5 cells either infected with TULV or transiently expressing NSs were decreased. These data demonstrate that Tula and Puumala hantaviruses have a functional NSs ORF. The findings may explain why the NSs ORF has been preserved in the genome of most hantaviruses during their long evolution and why hantavirus-infected cells secrete relatively low levels of IFNs. (c) 2007 Wiley-Liss, Inc.

  12. Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc.

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    Pablo Guardado-Calvo

    2016-10-01

    Full Text Available Hantaviruses are zoonotic viruses transmitted to humans by persistently infected rodents, giving rise to serious outbreaks of hemorrhagic fever with renal syndrome (HFRS or of hantavirus pulmonary syndrome (HPS, depending on the virus, which are associated with high case fatality rates. There is only limited knowledge about the organization of the viral particles and in particular, about the hantavirus membrane fusion glycoprotein Gc, the function of which is essential for virus entry. We describe here the X-ray structures of Gc from Hantaan virus, the type species hantavirus and responsible for HFRS, both in its neutral pH, monomeric pre-fusion conformation, and in its acidic pH, trimeric post-fusion form. The structures confirm the prediction that Gc is a class II fusion protein, containing the characteristic β-sheet rich domains termed I, II and III as initially identified in the fusion proteins of arboviruses such as alpha- and flaviviruses. The structures also show a number of features of Gc that are distinct from arbovirus class II proteins. In particular, hantavirus Gc inserts residues from three different loops into the target membrane to drive fusion, as confirmed functionally by structure-guided mutagenesis on the HPS-inducing Andes virus, instead of having a single "fusion loop". We further show that the membrane interacting region of Gc becomes structured only at acidic pH via a set of polar and electrostatic interactions. Furthermore, the structure reveals that hantavirus Gc has an additional N-terminal "tail" that is crucial in stabilizing the post-fusion trimer, accompanying the swapping of domain III in the quaternary arrangement of the trimer as compared to the standard class II fusion proteins. The mechanistic understandings derived from these data are likely to provide a unique handle for devising treatments against these human pathogens.

  13. Sweden - Physics in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1995-11-15

    In its continual monitoring of physics in its Member States, the European Committee for Future Accelerators (ECFA) recently visited Sweden, where it met at the University of Lund in September. Physics in Sweden is flourishing, with both a long CERN tradition and excellent prospects for future collaboration. On the experimental side, about 80 researchers, including about 30 graduate students, out of a total of 110 (including 50 graduate students), concentrate on CERN for their work. The main centres of experimental activity are: Chalmers- Goteborg; Lund (particle physics and relativistic heavy ion groups), the Royal Institute of Technology - KTH - Stockholm, the University of Stockholm, and Uppsala. Engineering support staff in particle and highenergy nuclear physics number about 25. There is a strong Swedish participation (34 researchers from Lund, Stockholm, and Uppsala) in the Delphi experiment at LEP with a full commitment to higher energy running at LEP2, in the CP-LEAR experiment, JETSET studies at the LEAR low energy antiproton ring and in a LEAR hyperon experiment. Sweden is also well represented in CERN's extensive programme of nuclear and heavy ion physics, with 12 researchers active in the heavy ion programme, and a contingent in the SMC muon beam experiment. The strong Swedish interest in CERN's heavy ion programme was underlined by a special national contribution of 1.5M Swiss francs to the new lead ion injector. At lower energies, there is also good Swedish participation (mainly from the Chalmers Institute) in the Isolde online isotope separator. The national physics community has always appreciated CERN's diversified programmes and has greatly benefited as a result. For the future, there is an important involvement (some 40 physicists) in the ATLAS experiment at CERN's LHC collider. Swedish groups have been active in 11 research and development project for LHC physics. Sweden's heavy ion activity will continue at the RHIC heavy ion collider being

  14. Sweden - Physics in Sweden

    International Nuclear Information System (INIS)

    Anon.

    1995-01-01

    In its continual monitoring of physics in its Member States, the European Committee for Future Accelerators (ECFA) recently visited Sweden, where it met at the University of Lund in September. Physics in Sweden is flourishing, with both a long CERN tradition and excellent prospects for future collaboration. On the experimental side, about 80 researchers, including about 30 graduate students, out of a total of 110 (including 50 graduate students), concentrate on CERN for their work. The main centres of experimental activity are: Chalmers- Goteborg; Lund (particle physics and relativistic heavy ion groups), the Royal Institute of Technology - KTH - Stockholm, the University of Stockholm, and Uppsala. Engineering support staff in particle and highenergy nuclear physics number about 25. There is a strong Swedish participation (34 researchers from Lund, Stockholm, and Uppsala) in the Delphi experiment at LEP with a full commitment to higher energy running at LEP2, in the CP-LEAR experiment, JETSET studies at the LEAR low energy antiproton ring and in a LEAR hyperon experiment. Sweden is also well represented in CERN's extensive programme of nuclear and heavy ion physics, with 12 researchers active in the heavy ion programme, and a contingent in the SMC muon beam experiment. The strong Swedish interest in CERN's heavy ion programme was underlined by a special national contribution of 1.5M Swiss francs to the new lead ion injector. At lower energies, there is also good Swedish participation (mainly from the Chalmers Institute) in the Isolde online isotope separator. The national physics community has always appreciated CERN's diversified programmes and has greatly benefited as a result. For the future, there is an important involvement (some 40 physicists) in the ATLAS experiment at CERN's LHC collider. Swedish groups have been active in 11 research and development project for LHC physics. Sweden's heavy ion activity will continue at the RHIC

  15. Hantavirus del nuevo mundo: Ecología y epidemiología de un virus emergente en latinoamérica The New-World Hantaviruses: Ecology and epidemiology of an emerging virus in Latin America

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    Henry Puerta

    2006-08-01

    ían necesarios más datos para entender su diversidad y evolución.The hantaviruses are a group of emerging rodent-borne pathogens (family Bunyaviridae; Genus Hantavirus that are etiologic agents for hemorrhagic fever with renal syndrome (HFRS in Europe and Asia and hantavirus cardiopulmonary syndrome (HCPS in the Americas. HFRS is associated with rodents of the family Muridae, subfamilies Murinae and Arvicolinae; HPS is associated with rodents of the subfamily Sigmodontinae. Since the identification of HCPS in USA in 1993, a large number of cases of HPS and an increasing number of hantaviruses and rodent reservoir hosts have been identified in Central and South America. Epidemiologic studies have demonstrated important differences in frequency of infection with hantaviruses in both human and rodent host populations. Antibody prevalences in rodent and human populations may vary from less than 1% to more than 40%. Currently, more than 1500 cases of HCPS have been reported and more than 15 genetically distinct variants of hantaviruses, all associated with sigmodontine rodents, have been identified throughout the Americas. Several characteristics distinguish Latin American HCPS cases from the classical HCPS described for the first time in the USA. These include a variation in severity of disease from moderate and self-limiting to severe, the demonstration of person-to-person transmission, and a somewhat higher incidence of extrapulmonary clinical manifestations in the South American form of HCPS. Nevertheless, our understanding of hantaviruses in the Americas is still far from complete. The factors involved in the dynamics of these viruses in nature, their establishment and transmission within host populations and from hosts to humans, and the variable pathology of these viruses in humans are complex. It is likely that more hantaviruses will be described in the future, and much more data will be required in order to describe the diversity and evolution of this group of pathogens

  16. Self-reported infections during international travel and notifiable infections among returning international travellers, Sweden, 2009-2013.

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    Viktor Dahl

    Full Text Available We studied food and water-borne diseases (FWDs, sexually transmitted diseases (STDs, vector-borne diseases (VBDs and diseases vaccinated against in the Swedish childhood vaccination programme among Swedish international travellers, in order to identify countries associated with a high number of infections. We used the national database for notifiable infections to estimate the number of FWDs (campylobacteriosis, salmonellosis, giardiasis, shigellosis, EHEC, Entamoeba histolytica, yersinosis, hepatitis A, paratyphoid fever, typhoid fever, hepatitis E, listeriosis, cholera, STIs (chlamydia, gonorrhoea and acute hepatitis B, VBDs (dengue fever, malaria, West Nile fever, Japanese encephalitis and yellow fever and diseases vaccinated against in the Swedish childhood vaccination programme (pertussis, measles, mumps, rubella, diphtheria acquired abroad 2009-2013. We obtained number and duration of trips to each country from a database that monthly collects travel data from a randomly selected proportion of the Swedish population. We calculated number of infections per country 2009-2013 and incidence/million travel days for the five countries with the highest number of infections. Thailand had the highest number of FWDs (7,697, incidence 191/million travel days, STIs (1,388, incidence 34/million travel days and VBDs (358, incidence 9/million travel days. France had the highest number of cases of diseases vaccinated against in the Swedish childhood vaccination programme (8, 0.4/million travel days. Swedish travellers contracted most infections in Thailand. Special focus should be placed on giving advice to travellers to this destination.

  17. Epidemiologic investigation of an outbreak of goose parvovirus infection in Sweden.

    Science.gov (United States)

    Jansson, Désirée S; Feinstein, Ricardo; Kardi, Veronika; Mató, Tamás; Palya, Vilmos

    2007-06-01

    An outbreak of goose parvovirus (GPV) infection on a Swedish goose farm in the spring of 2004 increased the mortality rates from 2% in the early unaffected hatches to 90% and 99% respectively in the two hatches following virus introduction and 40% in goslings hatched later in the same breeding season. In this paper we describe the clinical observations, diagnostic procedures, and epidemiologic investigation carried out to elucidate the source of the infection. The diagnosis was confirmed by serology, virus isolation, and sequence analysis of a 493-bp-long fragment of the VP1 gene. Phylogenetically the causative virus was closely related to pathogenic GPV strains isolated in 2003 and 2004 from Poland and the United Kingdom, respectively. The Swedish isolate exhibited less homology with pathogenic strains from Hungary and Asia and with attenuated vaccine strains. The epidemiologic investigation showed that the virus was first introduced to a contract farm (farm A) and then was transferred with newly hatched goslings to the farm that had submitted the birds for necropsy (index farm). The exact time and source of the virus introduction to farm A could not be determined with absolute certainty. Possible sources of the infection included backyard goose eggs that had been delivered to farm A for subcontract incubation and hatching, wild geese that frequented the flock of breeding geese on pasture on farm A, and a clutch of Canada goose eggs (Branta canadensis) that had been produced by wild geese and was hatched in the same machine as the eggs produced by farm A.

  18. Infection prevention and control interventions in the first outbreak of methicillin-resistant Staphylococcus aureus infections in an equine hospital in Sweden.

    Science.gov (United States)

    Bergström, Karin; Nyman, Görel; Widgren, Stefan; Johnston, Christopher; Grönlund-Andersson, Ulrika; Ransjö, Ulrika

    2012-03-08

    The first outbreak of methicillin-resistant Staphylococcus aureus (MRSA) infection in horses in Sweden occurred in 2008 at the University Animal Hospital and highlighted the need for improved infection prevention and control. The present study describes interventions and infection prevention control in an equine hospital setting July 2008 - April 2010. This descriptive study of interventions is based on examination of policy documents, medical records, notes from meetings and cost estimates. MRSA cases were identified through clinical sampling and telephone enquiries about horses post-surgery. Prospective sampling in the hospital environment with culture for MRSA and genotyping of isolates by spa-typing and pulsed-field gel electrophoresis (PFGE) were performed. Interventions focused on interruption of indirect contact spread of MRSA between horses via staff and equipment and included: Temporary suspension of elective surgery; and identification and isolation of MRSA-infected horses; collaboration was initiated between authorities in animal and human public health, human medicine infection control and the veterinary hospital; extensive cleaning and disinfection was performed; basic hygiene and cleaning policies, staff training, equipment modification and interior renovation were implemented over seven months.Ten (11%) of 92 surfaces sampled between July 2008 and April 2010 tested positive for MRSA spa-type 011, seven of which were from the first of nine sampling occasions. PFGE typing showed the isolates to be the outbreak strain (9 of 10) or a closely related strain. Two new cases of MRSA infection occurred 14 and 19 months later, but had no proven connections to the outbreak cases. Collaboration between relevant authorities and the veterinary hospital and formation of an infection control committee with an executive working group were required to move the intervention process forward. Support from hospital management and the dedication of staff were essential for

  19. Spatial prediction and validation of zoonotic hazard through micro-habitat properties: where does Puumala hantavirus hole - up?

    Science.gov (United States)

    Khalil, Hussein; Olsson, Gert; Magnusson, Magnus; Evander, Magnus; Hörnfeldt, Birger; Ecke, Frauke

    2017-07-26

    To predict the risk of infectious diseases originating in wildlife, it is important to identify habitats that allow the co-occurrence of pathogens and their hosts. Puumala hantavirus (PUUV) is a directly-transmitted RNA virus that causes hemorrhagic fever in humans, and is carried and transmitted by the bank vole (Myodes glareolus). In northern Sweden, bank voles undergo 3-4 year population cycles, during which their spatial distribution varies greatly. We used boosted regression trees; a technique inspired by machine learning, on a 10 - year time-series (fall 2003-2013) to develop a spatial predictive model assessing seasonal PUUV hazard using micro-habitat variables in a landscape heavily modified by forestry. We validated the models in an independent study area approx. 200 km away by predicting seasonal presence of infected bank voles in a five-year-period (2007-2010 and 2015). The distribution of PUUV-infected voles varied seasonally and inter-annually. In spring, micro-habitat variables related to cover and food availability in forests predicted both bank vole and infected bank vole presence. In fall, the presence of PUUV-infected voles was generally restricted to spruce forests where cover was abundant, despite the broad landscape distribution of bank voles in general. We hypothesize that the discrepancy in distribution between infected and uninfected hosts in fall, was related to higher survival of PUUV and/or PUUV-infected voles in the environment, especially where cover is plentiful. Moist and mesic old spruce forests, with abundant cover such as large holes and bilberry shrubs, also providing food, were most likely to harbor infected bank voles. The models developed using long-term and spatially extensive data can be extrapolated to other areas in northern Fennoscandia. To predict the hazard of directly transmitted zoonoses in areas with unknown risk status, models based on micro-habitat variables and developed through machine learning techniques in

  20. Detection of Brazilian hantavirus by reverse transcription polymerase chain reaction amplification of N gene in patients with hantavirus cardiopulmonary syndrome

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    Marcos Lázaro Moreli

    2004-10-01

    Full Text Available We report a nested reverse transcription-polymerase chain reaction (RT-PCR assay for hantavirus using primers selected to match high homology regions of hantavirus genomes detected from the whole blood of hantavirus cardiopulmonary syndrome (HCPS patients from Brazil, also including the N gene nucleotide sequence of Araraquara virus. Hantavirus genomes were detected in eight out of nine blood samples from the HCPS patients by RT-PCR (88.9% positivity and in all 9 blood samples (100% positivity by nested-PCR. The eight amplicons obtained by RT-PCR (P1, P3-P9, including one obtained by nested-PCR (P-2 and not obtained by RT-PCR, were sequenced and showed high homology (94.8% to 99.1% with the N gene of Araraquara hantavirus. Although the serologic method ELISA is the most appropriate test for HCPS diagnosis, the use of nested RT-PCR for hantavirus in Brazil would contribute to the diagnosis of acute hantavirus disease detecting viral genomes in patient specimens as well as initial genomic characterization of circulating hantaviruses.

  1. Muleshoe Virus and Other Hantaviruses Associated with Neotomine or Sigmodontine Rodents in Texas.

    Science.gov (United States)

    Milazzo, Mary Louise; Cajimat, Maria N B; Richter, Martin H; Bradley, Robert D; Fulhorst, Charles F

    2017-10-01

    The broad objective of this study was to increase our knowledge of Muleshoe virus and other hantaviruses associated with cricetid rodents in Texas. Anti-hantavirus antibody was found in 38 (3.2%) of 1171 neotomine rodents and 6 (1.8%) of 332 sigmodontine rodents from 10 Texas counties; hantaviral RNA was detected in 23 (71.9%) of 32 antibody-positive rodents. Analyses of nucleocapsid protein gene sequences indicated Muleshoe virus infection in four hispid cotton rats (Sigmodon hispidus) from northern Texas; Bayou virus, three Texas marsh oryzomys (Oryzomys texensis) from the Gulf Coast; Limestone Canyon virus, five brush mice (Peromyscus boylii) from western Texas; and Sin Nombre virus-five Texas mice (P. attwateri), one Lacey's white-ankled deer mouse (P. laceianus), four white-footed mice (P. leucopus), and one fulvous harvest mouse (Reithrodontomys fulvescens) from northern, central, or southern Texas. The results of this study together with the results of a previous study revealed that Muleshoe virus, perhaps in association with S. hispidus, is distributed across northern Texas. Finally, the results of Bayesian analyses of glycoprotein precursor (GPC) gene sequences and pairwise comparisons of complete GPC (amino acid) sequences strengthened support for the notion that Muleshoe virus is distinct from Black Creek Canal virus, Bayou virus, and all other species included in the Bunyaviridae, genus Hantavirus.

  2. Preventing Hantavirus Pulmonary Syndrome (HPS)

    Science.gov (United States)

    ... Seoul Virus Infection Testing for Seoul Virus in Pet Rats: Information For Veterinarians Yosemite National Park Case Count Maps Epi ... or minimize contact with rodents in your home, workplace, or campsite. If rodents don’t find that ...

  3. Animal Models for the Study of Rodent-Borne Hemorrhagic Fever Viruses: Arenaviruses and Hantaviruses

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    Joseph W. Golden

    2015-01-01

    Full Text Available Human pathogenic hantaviruses and arenaviruses are maintained in nature by persistent infection of rodent carrier populations. Several members of these virus groups can cause significant disease in humans that is generically termed viral hemorrhagic fever (HF and is characterized as a febrile illness with an increased propensity to cause acute inflammation. Human interaction with rodent carrier populations leads to infection. Arenaviruses are also viewed as potential biological weapons threat agents. There is an increased interest in studying these viruses in animal models to gain a deeper understating not only of viral pathogenesis, but also for the evaluation of medical countermeasures (MCM to mitigate disease threats. In this review, we examine current knowledge regarding animal models employed in the study of these viruses. We include analysis of infection models in natural reservoirs and also discuss the impact of strain heterogeneity on the susceptibility of animals to infection. This information should provide a comprehensive reference for those interested in the study of arenaviruses and hantaviruses not only for MCM development but also in the study of viral pathogenesis and the biology of these viruses in their natural reservoirs.

  4. Novel Strain of Andes Virus Associated with Fatal Human Infection, Central Bolivia

    Science.gov (United States)

    Cruz, Cristhopher D.; Vallejo, Efrain; Agudo, Roberto; Vargas, Jorge; Blazes, David L.; Guevara, Carolina; Laguna-Torres, V. Alberto; Halsey, Eric S.; Kochel, Tadeusz J.

    2012-01-01

    To better describe the genetic diversity of hantaviruses associated with human illness in South America, we screened blood samples from febrile patients in Chapare Province in central Bolivia during 2008–2009 for recent hantavirus infection. Hantavirus RNA was detected in 3 patients, including 1 who died. Partial RNA sequences of small and medium segments from the 3 patients were most closely related to Andes virus lineages but distinct (1 hantaviruses; the highest prevalence was among agricultural workers. Because of the high level of human exposure to hantavirus strains and the severity of resulting disease, additional studies are warranted to determine the reservoirs, ecologic range, and public health effect of this novel strain of hantavirus. PMID:22515983

  5. Síndrome pulmonar por Hantavirus (Virus Río Mamoré en la Amazonía Peruana Hantavirus pulmonary syndrome (Rio Mamore Virus in the Peruvian Amazon region

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    Martín Casapía

    2012-09-01

    Full Text Available La hantavirosis es una infección viral zoonótica transmitida por roedores cuya forma clínica más letal es el síndrome pulmonar por Hantavirus (SPH. La variante río Mamoré es autóctona de Sudamérica y fue descrita en roedores sin asociarla a enfermedad en humanos. Se presenta dos casos de SPH causados por hantavirus río Mamoré en la Amazonía peruana en noviembre de 2011. En ambos casos, el diagnóstico confirmatorio fue molecular, efectuados en el Instituto Nacional de Salud de Perú. Se realizó análisis filogenético del fragmento de genoma viral y la evaluación histopatológica. Ambos pacientes evolucionaron a síndrome de distrés respiratorio del adulto y estado de choque refractario. Un paciente falleció y el otro se recuperó a los doce díasHantavirus infection is a viral zoonotic infection borne by rodents which most letal form clinical is the Hantavirus Pulmonary Syndrome (SPH, Spanish abbreviation. The Mamore River variant originates in South America and was found in rodents without any association to human diseases. Two cases of SPH were identified in the Peruvian Amazon region in November 2011. In both cases, a molecular diagnostic testing was conducted by the Instituto Nacional de Salud from Peru. A phylogenetic analysis of a viral genome fragment and a histopathological evaluation were conducted. Both patients developed adult respiratory distress syndrome and refractory shock. A patient died and another one recovered 12 days later

  6. Estimation of main diversification time-points of hantaviruses using phylogenetic analyses of complete genomes.

    Science.gov (United States)

    Castel, Guillaume; Tordo, Noël; Plyusnin, Alexander

    2017-04-02

    Because of the great variability of their reservoir hosts, hantaviruses are excellent models to evaluate the dynamics of virus-host co-evolution. Intriguing questions remain about the timescale of the diversification events that influenced this evolution. In this paper we attempted to estimate the first ever timing of hantavirus diversification based on thirty five available complete genomes representing five major groups of hantaviruses and the assumption of co-speciation of hantaviruses with their respective mammal hosts. Phylogenetic analyses were used to estimate the main diversification points during hantavirus evolution in mammals while host diversification was mostly estimated from independent calibrators taken from fossil records. Our results support an earlier developed hypothesis of co-speciation of known hantaviruses with their respective mammal hosts and hence a common ancestor for all hantaviruses carried by placental mammals. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Zunehmend mehr Hantavirus-Infektionen: Hinweise zu Vorsichtsmaßnahmen für Ornithologen und Feldbiologen

    OpenAIRE

    Bosch, Stefan

    2008-01-01

    Hantaviruses are transmitted to humans by infected rodents via faeces, urine or bites and cause severe illness. In Europe the most common disease is the nephropathia epidemica. Man can be infected by inhaling viruses in contaminated aerosols or soil particles. There has been a obvious increase of case numbers in Germany in 2007: more than 1660 cases where recorded by the Robert-Koch-Institut (vs. 72 in 2006 and 448 in 2005). Mostly working men where concerned. 60 % of all patients had to be t...

  8. Risk of self-reported Chlamydia trachomatis infection by social and lifestyle factors: a study based on survey data from young adults in Stockholm, Sweden.

    Science.gov (United States)

    Deogan, Charlotte; Cnattingius, Sven; Månsdotter, Anna

    2012-12-01

    To analyse the associations between demographic, socio-economic and lifestyle factors, and the risk of self-reported chlamydial infection among young adults (20-29 years old) in Stockholm, Sweden. This study was based on the Stockholm Public Health Survey of 2006 (N = 4278). Demographic factors (gender, age, and country of birth), socio-economic factors (individual and parental educational levels, individual income level, and employment status), and lifestyle factors (body mass index, mental health, alcohol consumption, and partnership status) were taken into account. Possible associations were analysed by logistic regression. The risk of self-reported chlamydial infection decreases with age, is higher among individuals both who personally, and whose parents, were educated to high school level compared to university level education, and is higher among those employed, unemployed or on sick-leave/pre-retired compared to students. The risk of chlamydial infection is also higher among subjects who report greater alcohol consumption, and those who live without a partner. After considering demographic, socio-economic and lifestyle factors, the associations with age, educational level, employment status and alcohol consumption are strong and statistically significant. Indicators of risk-taking behaviours, especially in settings with generally little educational ambition or options, should be incorporated in the design of STI prevention strategies.

  9. High Prevalence of Tula Hantavirus in Common Voles in The Netherlands.

    Science.gov (United States)

    Maas, Miriam; de Vries, Ankje; van Roon, Annika; Takumi, Katsuhisa; van der Giessen, Joke; Rockx, Barry

    2017-03-01

    Tula virus (TULV) is a zoonotic hantavirus. Knowledge about TULV in the Netherlands is very scarce. Therefore in 2014, 49 common voles (Microtus arvalis) from a region in the south of the Netherlands, and in 2015, 241 common voles from regions in the north of the Netherlands were tested with the TULV quantitative RT-PCR. In the southern region, prevalence of TULV was 41% (20/49). In the northern regions, prevalence ranged from 12% (4/34) to 45% (17/38). Phylogenetic analysis of the obtained sequences showed that the regions fall within different clusters. Voles from the south were also tested on-site for the presence of hantavirus antibodies, but serology results were poorly associated with qRT-PCR results. These findings suggest that TULV may be more widespread than previously thought. No human TULV cases have been reported thus far in the Netherlands, but differentiation between infection by TULV or the closely related Puumala virus is not made in humans in the Netherlands, thus cases may be misdiagnosed.

  10. Leptospira spp. in Small Mammals from Areas with Low and High Human Hantavirus Incidences in South-West Germany.

    Science.gov (United States)

    Obiegala, Anna; Albrecht, Christoph; Dafalla, Maysaa; Drewes, Stephan; Oltersdorf, Carolin; Turni, Hendrik; Imholt, Christian; Jacob, Jens; Wagner-Wiening, Christiane; Ulrich, Rainer G; Pfeffer, Martin

    2017-05-01

    Leptospirosis is caused by Leptospira spp. and is considered the most widespread zoonotic disease worldwide. It mimics nephropathia epidemica in humans, a disease mainly caused by Puumala hantavirus (PUUV). Small mammals are reservoirs for Leptospira spp. and PUUV. Seewis virus (SWSV) is a shrew-borne hantavirus with unknown pathogenicity. The objective of this study was to estimate the prevalence for Leptospira spp. and the frequency of Leptospira-hantavirus co-infections in small mammals collected at locations with high and low incidences in humans. In 2012 and 2013, 736 small mammals belonging to seven species (Apodemus flavicollis, Microtus agrestis, Microtus arvalis, Myodes glareolus, Sorex araneus, S. coronatus, and S. minutus) were collected at four high incidence sites (H1-H4) and four low (L1-L4) incidence sites for PUUV infection in humans. Kidney-derived DNA samples were tested for Leptospira spp. by real-time PCR targeting the lipl 32 gene and further analyzed by duplex PCR targeting the flaB and the secY genes. For the detection of Seewis virus, lung-derived DNA was tested via RT-PCR targeting the nucleocapsid gene. Altogether, 42 of the 736 small mammals including 27 of 660 bank voles and 11 of 66 shrews, were positive for Leptospira spp., while Sorex spp. (14.7%) showed significantly higher prevalences compared to bank voles (4.1%). Detected Leptospira spp. were pathogenic species other than L. kirschneri. Significantly more Leptospira-positive bank voles were found at H sites than at L sites. Altogether 22.2% of positive bank voles were infected with PUUV. Double infection of PUUV and Leptospira spp. occurrence in bank voles is 1.86 times (OR = 1.86; 95% CI: 0.72-4.73) more likely than infections with each pathogen separately. Leptospira- positive bank voles are focally positively associated with PUUV infection in bank voles and with human hantavirus cases. It should be considered that shrews may serve as Leptospira spp. reservoirs.

  11. "One-night stands" - risky trips between lust and trust: qualitative interviews with Chlamydia trachomatis infected youth in North Sweden.

    Science.gov (United States)

    Christianson, Monica; Johansson, Eva; Emmelin, Maria; Westman, Göran

    2003-01-01

    The aim of the study was to get a deeper understanding of sexual risk-taking, by interviewing young people diagnosed with Chlamydia trachomatis. This qualitative study was conducted at a youth clinic in Umeå, Sweden. Five young women and four men, aged 18-22, participated. In-depth interviews were performed. Open questions around certain themes were posed, such as thoughts about getting CT, sexual encounters, and attitudes towards condoms. Interviews were tape-recorded and transcribed verbatim. Data were analysed according to grounded theory. Norms, events, and emotions were explored. The goal was to develop credible and applicable concepts concerning sexual relationships, risk-taking, and experiences of CT. Informants revealed that behind their sexual risk-taking was a drive to "go steady". Lust and trust were the guidelines if sex was going to take place. When discussing "one-night stands" gender stereotypes occurred. Females were expected to be less forward compared with males. We found an uneven distribution of responsibility concerning condoms. Males expected females to be "condom promoters". By catching CT, females experienced guilt, while males felt content through knowing "the source of contamination". An important public health issue is to implement how males should play an equal part in reproductive health. General CT screening of males is one suggestion.

  12. Hantaviruses: an emerging public health threat in India? A review

    Indian Academy of Sciences (India)

    PRAKASH KUMAR

    is to increase awareness of these emerging pathogens and the threats they pose to the public health system. [Chandy S, Abraham P and ..... distribution of the hosts through international shipping routes. The majority of SEOV-related .... Dalrymple J M 1994 Serological relationships among viruses in the Hantavirus genus, ...

  13. Novel hantavirus identified in European bat species Nyctalus noctula

    Czech Academy of Sciences Publication Activity Database

    Straková, Petra; Dufková, L.; Širmarová, J.; Salát, J.; Bartonička, T.; Klempa, B.; Pfaff, F.; Höper, D.; Hoffmann, B.; Ulrich, R. G.; Růžek, Daniel

    2017-01-01

    Roč. 48, March (2017), s. 127-130 ISSN 1567-1348 Institutional support: RVO:68081766 ; RVO:60077344 Keywords : Hantavirus * Bat * Phylogenetic analysis * Emerging virus * Bat-borne virus Subject RIV: FN - Epidemiology, Contagious Diseases ; Clinical Immunology; EE - Microbiology, Virology (BC-A) OBOR OECD: Infectious Diseases; Virology (BC-A) Impact factor: 2.885, year: 2016

  14. Sweden's help

    International Nuclear Information System (INIS)

    1969-01-01

    The Government of Sweden has decided to provide funds for the Agency to use for agreed projects in developing countries, and the Board of Governors has authorized the Director General to conclude an agreement to bring the scheme into effect. The Agency will administer the funds and will select and process requests to be considered for their use; it will also be responsible for project supervision and control. Responsibility for implementing the agreement on behalf of the Swedish Government is entrusted to the Swedish International Development Authority (SIDA) which functions under the auspices of the Ministry of Foreign Affairs and administers Swedish bilateral technical, financial and humanitarian assistance. SIDA has already provided, or has agreed to provide, assistance for a number of Agency technical co-operation programmes and for the International Centre for Theoretical Physics in Trieste. (author)

  15. T Cells and Pathogenesis of Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever with Renal Syndrome

    OpenAIRE

    Francis A. Ennis; Masanori Terajima

    2011-01-01

    We previously hypothesized that increased capillary permeability observed in both hantavirus cardiopulmonary syndrome (HCPS) and hemorrhagic fever with renal syndrome (HFRS) may be caused by hantavirus-specific cytotoxic T cells attacking endothelial cells presenting viral antigens on their surface based on clinical observations and in vitro experiments. In HCPS, hantavirus-specific T cell responses positively correlated with disease severity. In HFRS, in one report, contrary to HCPS, T cell ...

  16. The Andes hantavirus NSs protein is expressed from the viral small mRNA by a leaky scanning mechanism.

    Science.gov (United States)

    Vera-Otarola, Jorge; Solis, Loretto; Soto-Rifo, Ricardo; Ricci, Emiliano P; Pino, Karla; Tischler, Nicole D; Ohlmann, Théophile; Darlix, Jean-Luc; López-Lastra, Marcelo

    2012-02-01

    The small mRNA (SmRNA) of all Bunyaviridae encodes the nucleocapsid (N) protein. In 4 out of 5 genera in the Bunyaviridae, the smRNA encodes an additional nonstructural protein denominated NSs. In this study, we show that Andes hantavirus (ANDV) SmRNA encodes an NSs protein. Data show that the NSs protein is expressed in the context of an ANDV infection. Additionally, our results suggest that translation initiation from the NSs initiation codon is mediated by ribosomal subunits that have bypassed the upstream N protein initiation codon through a leaky scanning mechanism.

  17. Survey for hantaviruses, tick-borne encephalitis virus, and Rickettsia spp. in small rodents in Croatia.

    Science.gov (United States)

    Svoboda, Petra; Dobler, Gerhard; Markotić, Alemka; Kurolt, Ivan-Christian; Speck, Stephanie; Habuš, Josipa; Vucelja, Marko; Krajinović, Lidija Cvetko; Tadin, Ante; Margaletić, Josip; Essbauer, Sandra

    2014-07-01

    In Croatia, several rodent- and vector-borne agents are endemic and of medical importance. In this study, we investigated hantaviruses and, for the first time, tick-borne encephalitis virus (TBEV) and Rickettsia spp. in small wild rodents from two different sites (mountainous and lowland region) in Croatia. In total, 194 transudate and tissue samples from 170 rodents (A. flavicollis, n=115; A. agrarius, n=2; Myodes glareolus, n=53) were tested for antibodies by indirect immunofluorescence assays (IIFT) and for nucleic acids by conventional (hantaviruses) and real-time RT-/PCRs (TBEV and Rickettsia spp.). A total of 25.5% (24/94) of the rodents from the mountainous area revealed specific antibodies against hantaviruses. In all, 21.3% (20/94) of the samples from the mountainous area and 29.0% (9/31) from the lowland area yielded positive results for either Puumala virus (PUUV) or Dobrava-Belgrade virus (DOBV) using a conventional RT-PCR. All processed samples (n=194) were negative for TBEV by IIFT or real-time RT-PCR. Serological evidence of rickettsial infection was detected in 4.3% (4/94) rodents from the mountainous region. Another 3.2% (3/94) rodents were positive for Rickettsia spp. by real-time PCR. None of the rodents (n=76) from the lowland area were positive for Rickettsia spp. by real-time PCR. Dual infection of PUUV and Rickettsia spp. was found in one M. glareolus from the mountainous area by RT-PCR and real-time PCR, respectively. To our knowledge, this is the first detection of Rickettsia spp. in small rodents from Croatia. Phylogenetic analyses of S- and M-segment sequences obtained from the two study sites revealed well-supported subgroups in Croatian PUUV and DOBV. Although somewhat limited, our data showed occurrence and prevalence of PUUV, DOBV, and rickettsiae in Croatia. Further studies are warranted to confirm these data and to determine the Rickettsia species present in rodents in these areas.

  18. Serum Cytokine Profiles Differentiating Hemorrhagic Fever with Renal Syndrome and Hantavirus Pulmonary Syndrome

    Directory of Open Access Journals (Sweden)

    Svetlana F. Khaiboullina

    2017-05-01

    Full Text Available Hantavirus infection is an acute zoonosis that clinically manifests in two primary forms, hemorrhagic fever with renal syndrome (HFRS and hantavirus pulmonary syndrome (HPS. HFRS is endemic in Europe and Russia, where the mild form of the disease is prevalent in the Tatarstan region. HPS is endemic in Argentina, as well as other countries of North and South American. HFRS and HPS are usually acquired via the upper respiratory tract by inhalation of virus-contaminated aerosol. Although the pathogenesis of HFRS and HPS remains largely unknown, postmortem tissue studies have identified endothelial cells as the primary target of infection. Importantly, cell damage due to virus replication, or subsequent tissue repair, has not been documented. Since no single factor has been identified that explains the complexity of HFRS or HPS pathogenesis, it has been suggested that a cytokine storm may play a crucial role in the manifestation of both diseases. In order to identify potential serological markers that distinguish HFRS and HPS, serum samples collected during early and late phases of the disease were analyzed for 48 analytes using multiplex magnetic bead-based assays. Overall, serum cytokine profiles associated with HPS revealed a more pro-inflammatory milieu as compared to HFRS. Furthermore, HPS was strictly characterized by the upregulation of cytokine levels, in contrast to HFRS where cases were distinguished by a dichotomy in serum cytokine levels. The severe form of hantavirus zoonosis, HPS, was characterized by the upregulation of a higher number of cytokines than HFRS (40 vs 21. In general, our analysis indicates that, although HPS and HFRS share many characteristic features, there are distinct cytokine profiles for these diseases. These profiles suggest a strong activation of an innate immune and inflammatory responses are associated with HPS, relative to HFRS, as well as a robust activation of Th1-type immune responses. Finally, the results

  19. Serologic survey of hantavirus in a rural population from the northern State of Mato Grosso, Brazil Pesquisa sorológica para hantavírus em uma população rural do norte do Estado do Mato Grosso, Brasil

    Directory of Open Access Journals (Sweden)

    Ioni Oliveira Santos

    2012-01-01

    Full Text Available INTRODUCTION: Hantavirus is a genus of ribonucleic acid (RNA viruses included in the family Bunyaviridae. Hantaviruses are rodent-borne zoonoses that, in the last 18 years, became an emergent public health problem in the Americas, causing a severe cardiopulmonary syndrome. This disease has no specific treatment and has a high case fatality. The transmission of hantavirus to man occurs by inhaling aerosols of rodent excreta. The aim of this study was to determine the prevalence of antibodies to hantavirus in the population of the rural settlement of Tupã in the county of Marcelândia, State of Mato Grosso, Brazil. METHODS: The participants of the serologic survey were visited at their homes and selected randomly among the settlement population. Blood samples of the participants were collected by venopuncture. The serum samples were tested by an IgG-ELISA using an N recombinant protein of Araraquara hantavirus as antigen, using the protocol previously established by Figueiredo et al. RESULTS: IgG antibodies to hantavirus were detected in 7 (13% of the 54 participants. The positivity was higher among men. It was observed that there was an association of seropositivity to hantavirus within the participants born in the south of Brazil. CONCLUSIONS: The results suggest that, in this rural area, everyone is exposed to the same risk of becoming infected with hantavirus, and, therefore, there is a need to intensify surveillance activities and education of the local people to prevent this viral infection.INTRODUÇÃO: Hantavirus é um gênero de vírus RNA incluído na família Bunyaviridae. Hantaviroses são zoonoses transmitidas por roedores que nos últimos 18 anos tornou-se um problema emergente da saúde pública nas Américas causando uma síndrome cardiopulmonar. Esta doença não tem nenhum tratamento específico e apresenta alta letalidade. A transmissão do hantavirus ao homem ocorre pela inalação de aerossóis dos excrementos de roedores. O

  20. Development and psychometric testing of a barriers to HIV testing scale among individuals with HIV infection in Sweden; The Barriers to HIV testing scale-Karolinska version.

    Science.gov (United States)

    Wiklander, Maria; Brännström, Johanna; Svedhem, Veronica; Eriksson, Lars E

    2015-11-19

    Barriers to HIV testing experienced by individuals at risk for HIV can result in treatment delay and further transmission of the disease. Instruments to systematically measure barriers are scarce, but could contribute to improved strategies for HIV testing. Aims of this study were to develop and test a barriers to HIV testing scale in a Swedish context. An 18-item scale was developed, based on an existing scale with addition of six new items related to fear of the disease or negative consequences of being diagnosed as HIV-infected. Items were phrased as statements about potential barriers with a three-point response format representing not important, somewhat important, and very important. The scale was evaluated regarding missing values, floor and ceiling effects, exploratory factor analysis, and internal consistencies. The questionnaire was completed by 292 adults recently diagnosed with HIV infection, of whom 7 were excluded (≥9 items missing) and 285 were included (≥12 items completed) in the analyses. The participants were 18-70 years old (mean 40.5, SD 11.5), 39 % were females and 77 % born outside Sweden. Routes of transmission were heterosexual transmission 63 %, male to male sex 20 %, intravenous drug use 5 %, blood product/transfusion 2 %, and unknown 9 %. All scale items had <3 % missing values. The data was feasible for factor analysis (KMO = 0.92) and a four-factor solution was chosen, based on level of explained common variance (58.64 %) and interpretability of factor structure. The factors were interpreted as; personal consequences, structural barriers, social and economic security, and confidentiality. Ratings on the minimum level (suggested barrier not important) were common, resulting in substantial floor effects on the scales. The scales were internally consistent (Cronbach's α 0.78-0.91). This study gives preliminary evidence of the scale being feasible, reliable and valid to identify different types of barriers to HIV testing.

  1. Spatial and temporal patterning of bank vole demography and the epidemiology of the Puumala hantavirus in northeastern France.

    Science.gov (United States)

    Augot, D; Sauvage, F; Boue, F; Bouloy, M; Artois, M; Demerson, J M; Combes, B; Coudrier, D; Zeller, H; Cliquet, F; Pontier, D

    2008-12-01

    Epidemiological data from bank voles, Myodes glareolus, naturally infected by the hantavirus Puumala (PUUV) were collected by a capture-mark-recapture protocol from 2000 to 2002 in the French department of Ardennes. Four monitored trapping sites were established in two forests located in two cantons (Flize and Monthermé). We captured 912 bank voles corresponding to 557 different individuals during 8820 trapping nights for an overall trapping success of 10.34%. The average PUUV seroprevalence was 22.4%. Characteristics of the system reported in North European countries are confirmed in France. PUUV seroprevalence and abundance of rodents appeared weakly linked. Adult voles were more frequently antibody-positive, but no difference between sexes was established. Anti-PUUV seropositive voles were captured and high seroprevalence was observed from both forests, without human infection reported in Flize canton during the study. One site among the four exhibited peculiar infection dynamics, where vole weight and infection risk were negatively correlated.

  2. Policing football in Sweden

    DEFF Research Database (Denmark)

    Stott, Clifford; Havelund, Jonas; Lundberg, Filip

    2016-01-01

    of football policing in Sweden. Central to these is the empowerment and coordination of dialogue based approaches to the policing of football supporters in Sweden. The report points out that this is an area of crowd policing where Sweden are global leaders having influenced how policing is conducted in other...

  3. Changes in Diversification Patterns and Signatures of Selection during the Evolution of Murinae-Associated Hantaviruses

    Directory of Open Access Journals (Sweden)

    Guillaume Castel

    2014-03-01

    Full Text Available In the last 50 years, hantaviruses have significantly affected public health worldwide, but the exact extent of the distribution of hantavirus diseases, species and lineages and the risk of their emergence into new geographic areas are still poorly known. In particular, the determinants of molecular evolution of hantaviruses circulating in different geographical areas or different host species are poorly documented. Yet, this understanding is essential for the establishment of more accurate scenarios of hantavirus emergence under different climatic and environmental constraints. In this study, we focused on Murinae-associated hantaviruses (mainly Seoul Dobrava and Hantaan virus using sequences available in GenBank and conducted several complementary phylogenetic inferences. We sought for signatures of selection and changes in patterns and rates of diversification in order to characterize hantaviruses’ molecular evolution at different geographical scales (global and local. We then investigated whether these events were localized in particular geographic areas. Our phylogenetic analyses supported the assumption that RNA virus molecular variations were under strong evolutionary constraints and revealed changes in patterns of diversification during the evolutionary history of hantaviruses. These analyses provide new knowledge on the molecular evolution of hantaviruses at different scales of time and space.

  4. How People Get Hantavirus Pulmonary Syndrome (HPS)

    Science.gov (United States)

    ... Preventing Seoul Virus Infection in Pet Rats and People FAQs: Seoul Virus Cleaning Up After Pet Rodents to Reduce the Risk of Seoul Virus ... Bolivia, Brazil, Chile, Panama, Paraguay, and Uruguay. Can pets ... rodents into contact with people if they catch such animals and carry them ...

  5. Landscape and regional environmental analysis of the spatial distribution of hantavirus human cases in Europe

    Directory of Open Access Journals (Sweden)

    Caroline Brigitte Zeimes

    2015-03-01

    Full Text Available Background: In Europe, the most prevalent hantavirus, Puumala virus, is transmitted by bank voles and causes nephropathia epidemica in human. The European spatial distribution of nephropathia epidemica is investigated here for the first time with a rich set of environmental variables. Methods: The influence of variables at the landscape and regional level is studied through multilevel logistic regression and further information on their effects across the different European ecoregions is obtained by comparing an overall niche model (boosted regression trees with regressions by ecoregion. Results: The presence of nephropathia epidemica is likely in populated regions with well-connected forests, more intense vegetation activity, low soil water content, mild summers and cold winters. In these regions, landscapes with a higher proportion of built-up areas in forest ecotones and lower minimum temperature in winter are expected to be more at risk. Climate and forest connectivity have a stronger effect at the regional level. If variables are staying at their current values, the models predict that nephropathia epidemica may know intensification but should not spread (although Southern Sweden, the Norwegian coast and the Netherlands should be kept under watch.Conclusions: Models indicate that large-scale modeling can lead to a very high predictive power. At large scale, the effect of one variable on disease may follow three response scenarios: the effect may be the same across the entire study area; the effect can change according to the variable value, and the effect can change depending on local specificities. Each of these scenarios impacts large-scale modeling differently.

  6. Country report: Sweden

    International Nuclear Information System (INIS)

    1993-01-01

    Sweden has twelve nuclear power reactors with a combined capacity of 9900 MW net electric power. According to a resolution passed by parliament in 1980, Sweden will terminate its use of nuclear power in the year 2010, at the latest. According to generally accepted guidelines, the spent nuclear fuel will be kept in interim storage for approximately 40 years after which, according to present plans, it will be deposited in geological formations in Sweden

  7. Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil

    Directory of Open Access Journals (Sweden)

    Felipe Alves Morais

    2016-01-01

    Full Text Available Brazil has reported more than 1,600 cases of hantavirus cardiopulmonary syndrome (HPS since 1993, with a 39% rate of reported fatalities. Using a recombinant nucleocapsid protein of Araraquara virus, we performed ELISA to detect IgG antibodies against hantavirus in human sera. The aim of this study was to analyze hantavirus antibody levels in inhabitants from a tropical area (Amazon region in Rondônia state and a subtropical (Atlantic Rain Forest region in São Paulo state, Brazil. A total of 1,310 serum samples were obtained between 2003 and 2008 and tested by IgG-ELISA, and 82 samples (6.2%, of which 62 were from the tropical area (5.8% and 20 from the subtropical area (8.3%, tested positive. Higher levels of hantavirus antibody were observed in inhabitants of the populous subtropical areas compared with those from the tropical areas in Brazil.

  8. Mapas de riesgo para Hantavirus en el Parque Nacional Conguillío, sur de Chile Hantavirus risk maps for Conguillío National Park, southern Chile

    Directory of Open Access Journals (Sweden)

    ANDRÉS MUÑOZ-PEDREROS

    2007-09-01

    valor de cada variable utilizando la misma de ponderación en cada una de ellas (e.g., uso del suelo, habitat del reservorio, seropositividad del reservorio, casos y asentamientos humanos. Presentamos un mapa de riesgo que señala como principales áreas de riesgo, precisamente donde se emplaza la infraestructura turística principal de este visitado parqueThe risk of infection with Hantavirus depends on factors that determine a probability of contagion with the reservoirs: (a the vegetation structure and the land use as a primary scene, where specific factors such as composition, structure and density of the vegetation describe elements related to the habitat of the reservoirs, (b The existence of populations of reservoir rodents, (c Human establishments, such as availability and density of roads, inhabited areas or human presence (e.g., houses, warehouses. These three factors, brought together, provide the necessary facts to establish the risk. It is important to consider that these factors have a dynamics of seasonal change during the year and natural and man-made environmental modifications. In this way, we seek to understand the risk to which humans beings are submitted in the rural space. The spatial models correspond to representations of the reality observed in a certain area and determined to diverse geographical, topographic, biological, climatic factors, etc. The aim of this study was to establish potential sectors of risk to Hantavirus in a national park of the Region IX of Chile using thematic maps of environmental variables in a Geographical Information System to analyze aereal photograhs by means of photo interpretation, transference, digitalization and graphical-alphanumerical database managing. The vector layer was rasterized using a pixel size of 50 m. The map of risk was constructed using an additive model of layers through the Model Builder 1.0 software, an extension of Arc View 3.2. The base of the procedure was the arithmetic overlay process what

  9. Lone mothers in Sweden

    DEFF Research Database (Denmark)

    Burström, B; Diderichsen, Finn; Shouls, S

    1999-01-01

    To study trends in the health and socioeconomic circumstances of lone mothers in Sweden over the years 1979-1995, and to make comparisons with couple mothers over the same period.......To study trends in the health and socioeconomic circumstances of lone mothers in Sweden over the years 1979-1995, and to make comparisons with couple mothers over the same period....

  10. Hantavirus en roedores de la Octava Región de Chile Hantavirus in rodents of the VIII Region of Chile

    Directory of Open Access Journals (Sweden)

    JUAN CARLOS ORTIZ

    2004-06-01

    Full Text Available La Octava Región de Chile corresponde a la segunda región con el mayor número de casos de Síndrome Cardiopulmonar por Hantavirus (SCPH. Por tal motivo se realizó un estudio para detectar la presencia de anticuerpos contra hantavirus en roedores y su distribución local en la Octava Región. El estudio comprendió las cuatro provincias de la región y consideró once sitios de muestreo. Se capturaron siete especies de roedores, Abrothrix olivaceus fue la más abundante seguida de Oligoryzomys longicaudatus. De los 300 roedores analizados, cinco ejemplares (1,66 % resultaron ser positivos a hantavirus y correspondieron a tres especies de sigmodontinos: a saber, Loxodontomys micropus, que corresponde al único registro de este tipo para la especie en Chile, Abrotrix longipilis y Oligoryzomys longicaudatusThe Eight Region has the second highest number of cases of Hantavirus Cardiopulmonary Syndrome (HCPS in humans for Chile. A study was performed to identify the number of rodents serologically positive to hantavirus and their local distribution in this region. To achieve this goal, we sampled eleven sites in the four provinces of the region. Seven rodents species were collected, with Abrothrix olivaceus presenting the largest number of captures followed by Oligoryzomys longicaudatus. Of the 300 rodents analyzed, five (1.66 % were sero-positives to hantavirus and belonged to three different sigmodontine species: Abrothrix longipilis, O. longicaudatus, and Loxodontomys micropus. No previous records of seropositive L. micropus existed.

  11. Energy in Sweden 2010

    Energy Technology Data Exchange (ETDEWEB)

    2010-11-15

    The annual Energy in Sweden report, and its sister publication, Energy in Sweden - Facts and Figures 2010 (STEM-ET--2010-46), are intended to provide decision makers, journalists, companies, teachers and the public with coherent and easily available information on developments in the energy sector. Most of the publication is based on official statistics up to and including 2009, complemented where possible by input reflecting current events and decisions up to the middle of 2010. Energy in Sweden presents facts about the use and supply of energy, present energy- and climate policy and policy measures, energy prices and energy markets, the impact of energy systems on the environment and an international outlook etc. See also the publication Energy in Sweden - Facts and Figures 2010 where the tabular data behind most of the diagrams in Energy in Sweden are presented

  12. Energy in Sweden 2009

    Energy Technology Data Exchange (ETDEWEB)

    2009-12-15

    The annual Energy in Sweden report, and its sister publication, Energy in Sweden: Facts and Figures (STEM-ET--2009-29), are intended to provide decision makers, journalists, companies, teachers and the public with coherent and easily available information on developments in the energy sector. Most of the publication is based on official statistics up to and including 2008, complemented where possible by input reflecting current events and decisions up to the middle of 2009. Energy in Sweden presents facts about the use and supply of energy, present energy- and climate policy and policy measures, energy prices and energy markets, the impact of energy systems on the environment and an international outlook etc. See also the publication Energy in Sweden - Facts and Figures 2009 where the tabular data behind most of the diagrams in Energy in Sweden are presented

  13. Bovine aortic endothelial cells are susceptible to Hantaan virus infection

    International Nuclear Information System (INIS)

    Bahr, U.; Muranyi, W.; Mueller, S.; Kehm, R.; Handermann, M.; Darai, G.; Zeier, M.

    2004-01-01

    Hantavirus serotype Hantaan (HTN) is one of the causative agents of hemorrhagic fever with renal syndrome (HFRS, lethality up to 10%). The natural host of HTN is Apodemus agrarius. Recent studies have shown that domestic animals like cattle are sporadically seropositive for hantaviruses. In the present study, the susceptibility of bovine aortic endothelial cells (BAEC) expressing α V β 3 -integrin to a HTN infection was investigated. Viral nucleocapsid protein and genomic RNA segments were detected in infected BAEC by indirect immunofluorescence assay, Western blot analysis, and reverse transcription-polymerase chain reaction (RT-PCR), respectively. The results of this study strongly support our previous observation on Puumala virus (PUU) that has been propagated efficiently in BAEC. These findings open a new window to contemplate the ecology of hantavirus infection and transmission route from animal to man

  14. Hantavirus pulmonary syndrome in Anajatuba, Maranhão, Brazil

    Directory of Open Access Journals (Sweden)

    MENDES Wellington S.

    2001-01-01

    Full Text Available The authors report a confirmed case of hantavirus pulmonary syndrome in the rural area of the municipality of Anajatuba, state of Maranhão. Two other suspected cases from the same region are also described. The confirmed case involved a previously healthy young woman who died with signs and symptoms of acute respiratory insufficiency 5 days after presenting fever, myalgia and a dry cough. The patient was a student who was helping her parents with work in the fields; it was a habit of the family to store rice inside the house. The suspected cases involved two first-degree relatives working as field hands who died of acute respiratory insufficiency 24 and 48 hours, respectively, after presenting fever, myalgia and a dry cough. Both stored rice and corn inside their home. People living in the region reported massive infestations with rats in the woods and fields.

  15. Hantavirus Pulmonary Syndrome in Argentina, 1995–2008

    Science.gov (United States)

    Bellomo, Carla M.; Cacace, María Luisa; Suárez, Paola; Bogni, Liliana; Padula, Paula J.

    2010-01-01

    We report a large case series of hantavirus pulmonary syndrome (HPS) in Argentina that was confirmed by laboratory restuls from 1995 through 2008. The geographic and temporal distribution of cases by age, sex, fatality rate, and risk factors for HPS was analyzed. A total of 710 cases were unequally distributed among 4 of the 5 Argentine regions. Different case-fatality rates were observed for each affected region, with a maximum rate of 40.5%. The male-to-female ratio for HPS case-patients was 3.7:1.0; the case-fatality rate was significantly higher for women. Agriculture-associated activities were most commonly reported as potential risk factors, especially among men of working age. Although HPS cases occurred predominantly in isolation, we identified 15 clusters in which strong relationships were observed between members, which suggests ongoing but limited person-to-person transmission. PMID:21122213

  16. Life-Threatening Sochi Virus Infections, Russia

    Science.gov (United States)

    Tkachenko, Evgeniy A.; Morozov, Vyacheslav G.; Yunicheva, Yulia V.; Pilikova, Olga M.; Malkin, Gennadiy; Ishmukhametov, Aydar A.; Heinemann, Patrick; Witkowski, Peter T.; Klempa, Boris; Dzagurova, Tamara K.

    2015-01-01

    Sochi virus was recently identified as a new hantavirus genotype carried by the Black Sea field mouse, Apodemus ponticus. We evaluated 62 patients in Russia with Sochi virus infection. Most clinical cases were severe, and the case-fatality rate was as high as 14.5%. PMID:26584463

  17. Linnaeus in Uppsala, Sweden.

    Science.gov (United States)

    Cohen, Paul; Cohen, Brenda

    1997-01-01

    Presents a brief life history of Carl Linnaeus, a professor of medicine and botany in Uppsala, Sweden. Highlights his work in developing a classification system for plants and animals, and his botanical lectures and demonstrations. (JRH)

  18. Ongoing spillover of Hantaan and Gou hantaviruses from rodents is associated with hemorrhagic fever with renal syndrome (HFRS in China.

    Directory of Open Access Journals (Sweden)

    Wen Wang

    Full Text Available BACKGROUND: Longquan City, Zhejiang province, China, has been seriously affected by hemorrhagic fever with renal syndrome (HFRS since the first cases were registered in 1974. To understand the epidemiology and emergence of HFRS in Longquan, which may be indicative of large parts of rural China, we studied long-term incidence patterns and performed a molecular epidemiological investigation of the causative hantaviruses in human and rodent populations. METHOD/PRINCIPAL FINDINGS: During 1974-2011, 1866 cases of HFRS were recorded in Longquan, including 20 deaths. In 2011, the incidence of HFRS remained high, with 19.61 cases/100,000 population, despite the onset of vaccination in 1997. During 1974-1998, HFRS cases in Longquan occurred mainly in winter, while in the past decade the peak of HFRS has shifted to the spring. Notably, the concurrent prevalence of rodent-borne hantaviruses in the region was also high. Phylogenetic analyses of viral sequences recovered from rodents in Longquan revealed the presence of novel genetic variants of Gou virus (GOUV in Rattus sp. rats and Hantaan virus (HTNV in the stripe field mice, respectively. Strikingly, viral sequences sampled from infected humans were very closely related to those from rodents. CONCLUSIONS/SIGNIFICANCE: HFRS represents an important public health problem in Longquan even after years of preventive measures. Our data suggest that continual spillover of the novel genetic variant of GOUV and the new genetic lineage of HTNV are responsible for the high prevalence of HFRS in humans. In addition, this is the first report of GOUV associated with human HFRS cases, and our data suggest that GOUV is now the major cause of HFRS in this region.

  19. Radiological physics in Sweden

    International Nuclear Information System (INIS)

    Walstam, Rune

    1980-01-01

    Development of radiological or radiation physics as a separate discipline in Sweden is outlined. Growth in number of hospital physicists is compared with that of some other countries for the period 1950-1975. The main duties of hospital physicists are described. Undergraduate and postgraduate courses in radiation physics in Sweden are discussed. A microtron and a multi-source cobalt-60 unit are described. (M.G.B.)

  20. Seroprevalencia de hantavirus en roedores y casos humanos en el sur de la Argentina Hantavirus seroprevalence in rodents and human cases in southern Argentina

    Directory of Open Access Journals (Sweden)

    Edmundo Larrieu

    2003-04-01

    Full Text Available En la Provincia de Río Negro, Argentina, se presentaron casos humanos de síndrome pulmonar por hantavirus (SPH en la región de la cordillera andino patagónica. El virus Andes ha sido identificado en la región, tanto en el roedor Oligoryzomys longicaudatus como en seres humanos, demostrándose la transmisión principalmente del roedor al hombre y la factibilidad de la transmisión de persona a persona. El objetivo del presente trabajo es presentar nueva información sobre especies de roedores portadores de hantavirus en Argentina, su prevalencia de anticuerpos para hantavirus (período 1999-2001 y la relación del tamaño de las poblaciones de roedores y su seroprevalencia con la ocurrencia de casos humanos (período 1996-2001. Para ello, se procedió a la colocación de 3973 trampas para captura viva de roedores, tipo sherman en seis operativos efectuados entre octubre de 1999 y mayo de 2001. Se obtuvieron muestras de sangre de los roedores las que fueron procesadas mediante enzimoinmunoensayo con antígenos elaborados a partir de virus Andes. Una síntesis de los resultados indica 397 roedores capturados, con un éxito de trampeo del 10% y una prevalencia de anticuerpos contra hantavirus del 1.0%. Se observaron importantes diferencias en las especies capturadas en cada una de las regiones. Se capturaron O. longicaudatus y A. Olivaceus seropositivos y O. flavescens y C. Laucha potencialmente portadores de hantavirus Se registraron 6 casos humanos en el período 1993-1995 (correspondientes a estudios retrospectivos, 21 casos se notificaron en el período 1996-1998 y 6 en el período 1999-2001 Se analiza la correlación entre ocurrencia de casos humanos, seroprevalencia en roedores y éxito de trampeo.In the Province of Río Negro, Argentina, human cases of hantavirus pulmonary syndrome (HPS have occurred in the region of the Patagonian Andean range. The Andes virus has been identified in the region, both in the rodent Oligoryzomys

  1. Kabbalah in Sweden

    Directory of Open Access Journals (Sweden)

    Thomas Karlsson

    2008-01-01

    Full Text Available This article examines the history of Kabbalah in Sweden. The reader is presented with an overall view to Kabbalah in Sweden: first, the Johannes Bureus and the Nordic Kabbalah, Kabbalah after Bureus, Kabbalistic literature, and last, Kabbalah in Sweden today. When the Kabbalah reached Sweden it was mainly the non-Jewish Kabbalah that gained influence, even if its Jewish roots were acknowledged. Johannes Bureus unites, in a similar fashion as do the Christian Kabbalists in continental Europe, Christian motifs with the symbolic world of the Kabbalah. Bureus, however, adds runes, ancient Norse gods and Gothic ideas in his own unique manner. The Kabbalah invites speculation and the search for correspondences which has caused the Kabbalah in Sweden to be united with a number of other traditions. Bureus combined the Kabbalah with runes and Gothicism; in the eighteenth and nineteenth centuries we can find the Kabbalah in Freemasonry and Esoteric societies, while the Kabbalah in the twentieth century and onwards has been associated with New Age, Parapsychology and Indian Mysticism. Apart from Bureus, most Kabbalists in Sweden have followed the trends that flourished in the rest of the world. Bureus was the first to create a specifically Swedish interpretation of the Kabbalah.

  2. Phylogeographic Diversity of Pathogenic and Non-Pathogenic Hantaviruses in Slovenia

    Science.gov (United States)

    Korva, Miša; Knap, Nataša; Resman Rus, Katarina; Fajs, Luka; Grubelnik, Gašper; Bremec, Matejka; Knapič, Tea; Trilar, Tomi; Avšič Županc, Tatjana

    2013-01-01

    Slovenia is a very diverse country from a natural geography point of view, with many different habitats within a relatively small area, in addition to major geological and climatic differences. It is therefore not surprising that several small mammal species have been confirmed to harbour hantaviruses: A. flavicollis (Dobrava virus), A. agrarius (Dobrava virus–Kurkino), M. glareolus (Puumala virus), S. areanus (Seewis virus), M. agrestis, M. arvalis and M. subterraneus (Tula virus). Three of the viruses, namely the Dobrava, Dobrava–Kurkino and Puumala viruses, cause disease in humans, with significant differences in the severity of symptoms. Due to changes in haemorrhagic fever with renal syndrome cases (HFRS) epidemiology, a detailed study on phylogenetic diversity and molecular epidemiology of pathogenic and non-pathogenic hantaviruses circulating in ecologically diverse endemic regions was performed. The study presents one of the largest collections of hantavirus L, M and S sequences obtained from hosts and patients within a single country. Several genetic lineages were determined for each hantavirus species, with higher diversity among non-pathogenic compared to pathogenic viruses. For pathogenic hantaviruses, a significant geographic clustering of human- and rodent-derived sequences was confirmed. Several geographic and ecological factors were recognized as influencing and limiting the formation of endemic areas. PMID:24335778

  3. Equilibrium and kinetics of Sin Nombre hantavirus binding at DAF/CD55 functionalized bead surfaces.

    Science.gov (United States)

    Buranda, Tione; Swanson, Scarlett; Bondu, Virginie; Schaefer, Leah; Maclean, James; Mo, Zhenzhen; Wycoff, Keith; Belle, Archana; Hjelle, Brian

    2014-03-10

    Decay accelerating factor (DAF/CD55) is targeted by many pathogens for cell entry. It has been implicated as a co-receptor for hantaviruses. To examine the binding of hantaviruses to DAF, we describe the use of Protein G beads for binding human IgG Fc domain-functionalized DAF ((DAF)₂-Fc). When mixed with Protein G beads the resulting DAF beads can be used as a generalizable platform for measuring kinetic and equilibrium binding constants of DAF binding targets. The hantavirus interaction has high affinity (24-30 nM; k(on) ~ 10⁵ M⁻¹ s⁻¹, k(off) ~ 0.0045 s⁻¹). The bivalent (DAF)₂-Fc/SNV data agree with hantavirus binding to DAF expressed on Tanoue B cells (K(d) = 14.0 nM). Monovalent affinity interaction between SNV and recombinant DAF of 58.0 nM is determined from competition binding. This study serves a dual purpose of presenting a convenient and quantitative approach of measuring binding affinities between DAF and the many cognate viral and bacterial ligands and providing new data on the binding constant of DAF and Sin Nombre hantavirus. Knowledge of the equilibrium binding constant allows for the determination of the relative fractions of bound and free virus particles in cell entry assays. This is important for drug discovery assays for cell entry inhibitors.

  4. Expansión geográfica del síndrome pulmonar por hantavirus en la Argentina: Informe del caso más austral Geographic expansion of hantavirus pulmonary syndrome in Argentina: The southernest case report

    Directory of Open Access Journals (Sweden)

    Carla Bellomo

    2009-12-01

    Full Text Available Desde 1995 se han informado más de 1000 casos de síndrome pulmonar por hantavirus (SPH en la Argentina, enfermedad grave y muchas veces fatal para los humanos. La mayoría de los casos fueron asociados al virus Andes (AND único hantavirus que ha sido informado como causante de transmisión persona a persona. Se han descrito varios linajes patogénicos del virus AND, de los cuales AND Sur, cuyo reservorio es el roedor Oligoryzomys longicaudatus, afecta a la región patagónica de Argentina y Chile. En el presente estudio se informan las manifestaciones clínicas y las características epidemiológicas de un caso de SPH. El objetivo fue describir la presentación clínica del caso, su entorno epidemiológico, el sitio probable de contagio, la variante viral implicada y su relación con los casos más cercanos notificados. Se realizó el seguimiento clínico, el diagnóstico serológico y molecular y la investigación epidemiológica, incluyendo un estudio de la población de roedores reservorios en las áreas involucradas. Se trató de una presentación clásica de SPH moderada, causada por el linaje viral AND sur y su secuencia nucleotídica se comparó con casos del sur argentino y chileno. El caso de hantavirus investigado resultó ser el más austral (48° 46´ 1.2´´ S; 70° 15´ 0´´ O notificado hasta el momento e involucró a una nueva provincia argentina.Since 1995 more than 1000 cases of hantavirus pulmonary syndrome (HPS were reported in Argentina, a severe disease and often fatal to humans. Most cases were associated with Andes virus (AND that caused few events of person-to-person transmission. Several lineages of pathogenic AND viruses have been described, including AND South, hosted by the rodent Oligoryzomys longicaudatus which affects the Patagonian region of Argentina and Chile. We studied the clinical and epidemiological characteristics of a HPS case. The objective was to describe the clinical presentation of the case, its

  5. Multiple infections of rodents with zoonotic pathogens in Austria.

    Science.gov (United States)

    Schmidt, Sabrina; Essbauer, Sandra S; Mayer-Scholl, Anne; Poppert, Sven; Schmidt-Chanasit, Jonas; Klempa, Boris; Henning, Klaus; Schares, Gereon; Groschup, Martin H; Spitzenberger, Friederike; Richter, Dania; Heckel, Gerald; Ulrich, Rainer G

    2014-07-01

    Rodents are important reservoirs for a large number of zoonotic pathogens. We examined the occurrence of 11 viral, bacterial, and parasitic agents in rodent populations in Austria, including three different hantaviruses, lymphocytic choriomeningitis virus, orthopox virus, Leptospira spp., Borrelia spp., Rickettsia spp., Bartonella spp., Coxiella burnetii, and Toxoplasma gondii. In 2008, 110 rodents of four species (40 Clethrionomys glareolus, 29 Apodemus flavicollis, 26 Apodemus sylvaticus, and 15 Microtus arvalis) were trapped at two rural sites in Lower Austria. Chest cavity fluid and samples of lung, spleen, kidney, liver, brain, and ear pinna skin were collected. We screened selected tissue samples for hantaviruses, lymphocytic choriomeningitis virus, orthopox viruses, Leptospira, Borrelia, Rickettsia, Bartonella spp., C. burnetii, and T. gondii by RT-PCR/PCR and detected nucleic acids of Tula hantavirus, Leptospira spp., Borrelia afzelii, Rickettsia spp., and different Bartonella species. Serological investigations were performed for hantaviruses, lymphocytic choriomeningitis virus, orthopox viruses, and Rickettsia spp. Here, Dobrava-Belgrade hantavirus-, Tula hantavirus-, lymphocytic choriomeningitis virus-, orthopox virus-, and rickettsia-specific antibodies were demonstrated. Puumala hantavirus, C. burnetii, and T. gondii were neither detected by RT-PCR/PCR nor by serological methods. In addition, multiple infections with up to three pathogens were shown in nine animals of three rodent species from different trapping sites. In conclusion, these results show that rodents in Austria may host multiple zoonotic pathogens. Our observation raises important questions regarding the interactions of different pathogens in the host, the countermeasures of the host's immune system, the impact of the host-pathogen interaction on the fitness of the host, and the spread of infectious agents among wild rodents and from those to other animals or humans.

  6. Energy in Sweden 2008

    Energy Technology Data Exchange (ETDEWEB)

    2008-12-15

    Energy in Sweden is published annually and is intended to provide decision-makers, journalists, companies, teachers and the general public with a coherent and easily available source of information on developments in the energy sector. Statistics are presented up to and including year 2007, when possible. Energy in Sweden presents facts about the use and supply of energy, present energy- and climate policy and policy measures, energy prices and energy markets, the impact of energy systems on the environment, and an international outlook. A new chapter for this year is Secure energy supply. There is also a chapter on Sweden's share of renewable energy calculated with the definition by the European commission. See also the publication Energy in Sweden - Facts and Figures 2008 where the tabular data behind most of the diagrams in Energy in Sweden are presented. Most of the publication is based on official statistics up to and including 2007, complemented where possible by input reflecting current events and decisions up to the middle of 2008

  7. Hantavirus pulmonary syndrome clinical findings: evaluating a surveillance case definition.

    Science.gov (United States)

    Knust, Barbara; Macneil, Adam; Rollin, Pierre E

    2012-05-01

    Clinical cases of hantavirus pulmonary syndrome (HPS) can be challenging to differentiate from other acute respiratory diseases, which can lead to delays in diagnosis, treatment, and disease reporting. Rapid onset of severe disease occurs, at times before diagnostic test results are available. This study's objective was to examine the clinical characteristics of patients that would indicate HPS to aid in detection and reporting. Test results of blood samples from U.S. patients suspected of having HPS submitted to the Centers for Disease Control and Prevention from 1998-2010 were reviewed. Patient information collected by case report forms was compared between HPS-confirmed and test-negative patients. Diagnostic sensitivity, specificity, predictive values, and likelihood ratios were calculated for individual clinical findings and combinations of variables. Of 567 patients included, 36% were HPS-confirmed. Thrombocytopenia, chest x-rays with suggestive signs, and receiving supplemental oxygenation were highly sensitive (>95%), while elevated hematocrit was highly specific (83%) in detecting HPS. Combinations that maximized sensitivity required the presence of thrombocytopenia. Using a national sample of suspect patients, we found that thrombocytopenia was a highly sensitive indicator of HPS and should be included in surveillance definitions for suspected HPS. Using a sensitive suspect case definition to identify potential HPS patients that are confirmed by highly specific diagnostic testing will ensure accurate reporting of this disease.

  8. Energy in Sweden 2007

    Energy Technology Data Exchange (ETDEWEB)

    2007-11-15

    Energy in Sweden is published annually, and is intended to provide decision-makers, journalists and the public with coherent and easily available information on developments in the energy sector. Most of the publication is based on official statistics up to and including 2006, complemented where possible by input reflecting current events and decisions up to the middle of 2007. The publication consists of eight chapters: Current energy and climate policy areas; Policy measures and incentives; Sweden's energy balance; Energy use; Energy markets; An international perspective; The environmental situation; and, Energy facts

  9. Energy in Sweden 2007

    Energy Technology Data Exchange (ETDEWEB)

    2007-11-15

    Energy in Sweden is published annually, and is intended to provide decision-makers, journalists and the public with coherent and easily available information on developments in the energy sector. Most of the publication is based on official statistics up to and including 2006, complemented where possible by input reflecting current events and decisions up to the middle of 2007. The publication consists of eight chapters: Current energy and climate policy areas; Policy measures and incentives; Sweden's energy balance; Energy use; Energy markets; An international perspective; The environmental situation; and, Energy facts

  10. Experimental Andes virus infection in deer mice: characteristics of infection and clearance in a heterologous rodent host.

    Directory of Open Access Journals (Sweden)

    Jessica R Spengler

    Full Text Available New World hantaviruses can cause hantavirus cardiopulmonary syndrome with high mortality in humans. Distinct virus species are hosted by specific rodent reservoirs, which also serve as the vectors. Although regional spillover has been documented, it is unknown whether rodent reservoirs are competent for infection by hantaviruses that are geographically separated, and known to have related, but distinct rodent reservoir hosts. We show that Andes virus (ANDV of South America, carried by the long tailed pygmy rice rat (Oligoryzomys longicaudatus, infects and replicates in vitro and in vivo in the deer mouse (Peromyscus maniculatus, the reservoir host of Sin Nombre virus (SNV, found in North America. In experimentally infected deer mice, viral RNA was detected in the blood, lung, heart and spleen, but virus was cleared by 56 days post inoculation (dpi. All of the inoculated deer mice mounted a humoral immune response by 14 dpi, and produced measurable amounts of neutralizing antibodies by 21 dpi. An up-regulation of Ccl3, Ccl4, Ccl5, and Tgfb, a strong CD4⁺ T-cell response, and down-regulation of Il17, Il21 and Il23 occurred during infection. Infection was transient with an absence of clinical signs or histopathological changes. This is the first evidence that ANDV asymptomatically infects, and is immunogenic in deer mice, a non-natural host species of ANDV. Comparing the immune response in this model to that of the immune response in the natural hosts upon infection with their co-adapted hantaviruses may help clarify the mechanisms governing persistent infection in the natural hosts of hantaviruses.

  11. Sweden - energy situation 1986

    International Nuclear Information System (INIS)

    1988-01-01

    The energy situation of Sweden is reviewed on the basis of relevant data. Data on the country's national and international energy policy are followed by an outline of trends in energy sources and electric power generation. Key figures are presented on the country's external trade and balance of payments. (UA) [de

  12. Endemic Tularemia, Sweden, 2003

    OpenAIRE

    Payne, Lara; Arneborn, Malin; Tegnell, Anders; Giesecke, Johan

    2005-01-01

    Tularemia cases have been reported in Sweden since 1931, but no cyclical patterns can be identified. In 2003, the largest outbreak of tularemia since 1967 occurred, involving 698 cases. Increased reports were received from tularemia-nonendemic areas. Causal factors for an outbreak year and associated geographic distribution are not yet understood.

  13. Sweden after the referendum

    International Nuclear Information System (INIS)

    Ragnarson, P.

    1981-01-01

    Interest in the nuclear programme has slumped in the public and political arenas since the referendum in March 1980. How Sweden is now preparing for the implementation of the limited 12-reactor programme, and the associated fuel cycle, in particular the world's first away from reactor irradiated fuel storage, is discussed. (U.K.)

  14. Detection of shrew-borne hantavirus in Eurasian pygmy shrew (Sorex minutus) in Central Europe

    Czech Academy of Sciences Publication Activity Database

    Radosa, L.; Schlegel, M.; Gebauer, P.; Ansorge, H.; Heroldová, Marta; Jánová, Eva; Stanko, M.; Mošanský, L.; Fričová, J.; Pejčoch, M.; Suchomel, J.; Purchart, L.; Groschup, M. H.; Krüger, D. H.; Ulrich, R. G.; Klempa, B.

    2013-01-01

    Roč. 19, October (2013), s. 403-410 ISSN 1567-1348 Institutional support: RVO:68081766 Keywords : Hantavirus * shrew Sorex minutus * Asikkala virus * Cental Europe Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine Impact factor: 3.264, year: 2013

  15. Molecular evolution of Puumala hantavirus in Fennoscandia: phylogenetic analysis of strains from two recolonization routes

    DEFF Research Database (Denmark)

    Asikainen, Kari; Hänninen, Tarja; Henttonen, Heikki

    2000-01-01

    Like other members of the genus Hantavirus in the family Bunyaviridae, Puumala virus (PUUV) is thought to be co-evolving with its natural host, the bank vole Clethrionomys glareolus. To gain insight into the evolutionary history of PUUV in northern Europe during the last post-glacial period, we h...

  16. Drotrecogin alpha (activated) in two patients with the hantavirus cardiopulmonary syndrome

    OpenAIRE

    McDermid, Robert C; Gibney, RT Noel; Brisebois, Ronald J; Skjodt, Neil M

    2006-01-01

    Hantavirus cardiopulmonary syndrome (HCPS) is associated with rapid cardiopulmonary collapse from endothelial injury, resulting in massive capillary leak, shock and severe hypoxemic respiratory failure. To date, treatment remains supportive and includes mechanical ventilation, vasopressors and extracorporeal membrane oxygenation, with mortality approaching 50%. Two HCPS survivors initially given drotrecogin alpha (activated) (DAA) for presumed bacterial septic shock are described. Vasoactive ...

  17. Differential Regulation of PAI-1 in Hantavirus Cardiopulmonary Syndrome and Hemorrhagic Fever With Renal Syndrome

    OpenAIRE

    Bellomo, Carla; Korva, Miša; Papa, Anna; Mäkelä, Satu; Mustonen, Jukka; Avšič-Županc, Tatjana; Vaheri, Antti; Martinez, Valeria P; Strandin, Tomas

    2018-01-01

    Abstract We analyzed the levels of circulating tissue plasminogen activator (tPA) and plasminogen activator inhibitor (PAI)–1 in acute hantavirus cardiopulmonary syndrome (HCPS) and hemorrhagic fever with renal syndrome (HFRS). The levels of tPA commonly increased in both diseases, whereas PAI-1 correlated with disease severity in HCPS but not in HFRS.

  18. Current wheeze, asthma, respiratory infections, and rhinitis among adults in relation to inspection data and indoor measurements in single-family houses in Sweden-The BETSI study.

    Science.gov (United States)

    Wang, J; Engvall, K; Smedje, G; Nilsson, H; Norbäck, D

    2017-07-01

    In the Swedish Building Energy, Technical Status and Indoor environment study, a total of 1160 adults from 605 single-family houses answered a questionnaire on respiratory health. Building inspectors investigated the homes and measured temperature, air humidity, air exchange rate, and wood moisture content (in attic and crawl space). Moisture load was calculated as the difference between indoor and outdoor absolute humidity. Totally, 7.3% were smokers, 8.7% had doctor' diagnosed asthma, 11.2% current wheeze, and 9.5% current asthma symptoms. Totally, 50.3% had respiratory infections and 26.0% rhinitis. The mean air exchange rate was 0.36/h, and the mean moisture load 1.70 g/m 3 . Damp foundation (OR=1.79, 95% CI 1.16-2.78) was positively associated while floor constructions with crawl space (OR=0.49, 95% CI 0.29-0.84) was negatively associated with wheeze. Concrete slabs with overlying insulation (OR=2.21, 95% CI 1.24-3.92) and brick façade (OR=1.71, 95% CI 1.07-2.73) were associated with rhinitis. Moisture load was associated with respiratory infections (OR=1.21 per 1 g/m 3 , 95% CI 1.04-1.40) and rhinitis (OR=1.36 per 1 g/m 3 , 95% CI 1.02-1.83). Air exchange rate was associated with current asthma symptoms (OR=0.85 per 0.1/h, 95% CI 0.73-0.99). Living in homes with damp foundation, concrete slabs with overlying insulation, brick façade, low ventilation flow, and high moisture load are risk factors for asthma, rhinitis, and respiratory infections. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  19. Landscape, Environmental and Social Predictors of Hantavirus Risk in São Paulo, Brazil.

    Directory of Open Access Journals (Sweden)

    Paula Ribeiro Prist

    Full Text Available Hantavirus Pulmonary Syndrome (HPS is a disease caused by Hantavirus, which are negative-sense RNA viruses in the family Bunyaviridae that are highly virulent to humans. Numerous factors modify risk of Hantavirus transmission and consequent HPS risk. Human-driven landscape change can foster transmission risk by increasing numbers of habitat generalist rodent species that serve as the principal reservoir host. Climate can also affect rodent population dynamics and Hantavirus survival, and a number of social factors can influence probability of HPS transmission to humans. Evaluating contributions of these factors to HPS risk may enable predictions of future outbreaks, and is critical to development of effective public health strategies. Here we rely on a Bayesian model to quantify associations between annual HPS incidence across the state of São Paulo, Brazil (1993-2012 and climate variables (annual precipitation, annual mean temperature, landscape structure metrics (proportion of native habitat cover, number of forest fragments, proportion of area planted with sugarcane, and social factors (number of men older than 14 years and Human Development Index. We built separate models for the main two biomes of the state (cerrado and Atlantic forest. In both biomes Hantavirus risk increased with proportion of land cultivated for sugarcane and HDI, but proportion of forest cover, annual mean temperature, and population at risk also showed positive relationships in the Atlantic forest. Our analysis provides the first evidence that social, landscape, and climate factors are associated with HPS incidence in the Neotropics. Our risk map can be used to support the adoption of preventive measures and optimize the allocation of resources to avoid disease propagation, especially in municipalities that show medium to high HPS risk (> 5% of risk, and aimed at sugarcane workers, minimizing the risk of future HPS outbreaks.

  20. Interacting factors associated with Low antibiotic prescribing for respiratory tract infections in primary health care - a mixed methods study in Sweden.

    Science.gov (United States)

    Strandberg, Eva Lena; Brorsson, Annika; André, Malin; Gröndal, Hedvig; Mölstad, Sigvard; Hedin, Katarina

    2016-07-18

    Prescribing of antibiotics for common infections varies widely, and there is no medical explanation. Systematic reviews have highlighted factors that may influence antibiotic prescribing and that this is a complex process. It is unclear how factors interact and how the primary care organization affects diagnostic procedures and antibiotic prescribing. Therefore, we sought to explore and understand interactions between factors influencing antibiotic prescribing for respiratory tract infections in primary care. Our mixed methods design was guided by the Triangulation Design Model according to Creswell. Quantitative and qualitative data were collected in parallel. Quantitative data were collected by prescription statistics, questionnaires to patients, and general practitioners' audit registrations. Qualitative data were collected through observations and semi-structured interviews. From the analysis of the data from the different sources an overall theme emerged: A common practice in the primary health care centre is crucial for low antibiotic prescribing in line with guidelines. Several factors contribute to a common practice, such as promoting management and leadership, internalized guidelines including inter-professional discussions, the general practitioner's diagnostic process, nurse triage, and patient expectation. These factors were closely related and influenced each other. The results showed that knowledge must be internalized and guidelines need to be normative for the group as well as for every individual. Low prescribing is associated with adapted and transformed guidelines within all staff, not only general practitioners. Nurses' triage and self-care advice played an important role. Encouragement from the management level stimulated inter-professional discussions about antibiotic prescribing. Informal opinion moulders talking about antibiotic prescribing was supported by the managers. Finally, continuous professional development activities were encouraged

  1. In vitro and in vivo activity of ribavirin against Andes virus infection.

    Directory of Open Access Journals (Sweden)

    David Safronetz

    Full Text Available Pathogenic hantaviruses are a closely related group of rodent-borne viruses which are responsible for two distinct diseases in humans, hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome (HPS, otherwise known as hantavirus cardiopulmonary syndrome, HCPS. The antiviral effect of ribavirin against Old World hantaviruses, most notably Hantaan virus, is well documented; however, only a few studies have addressed its inhibitory effect on New World hantaviruses. In the present study, we demonstrate that ribavirin is highly active against Andes virus (ANDV, an important etiological agent of HPS, both in vitro and in vivo using a lethal hamster model of HPS. Treatment of ANDV infected Vero E6 cells with ribavirin resulted in dose-dependent reductions in viral RNA and protein as well as virus yields with a half maximal inhibitory concentration between 5 and 12.5 µg ml(-1. In hamsters, treatment with as little as 5 mg kg(-1 day(-1 was 100% effective at preventing lethal HPS disease when therapy was administered by intraperitoneal injection from day 1 through day 10 post-infection. Significant reductions were observed in ANDV RNA and antigen positive cells in lung and liver tissues. Ribavirin remained completely protective when administered by intraperitoneal injections up to three days post-infection. In addition, we show that daily oral ribavirin therapy initiated 1 day post-infection and continuing for ten days is also protective against lethal ANDV disease, even at doses of 5 mg kg(-1 day(-1. Our results suggest ribavirin treatment is beneficial for postexposure prophylaxis against HPS-causing hantaviruses and should be considered in scenarios where exposure to the virus is probable. The similarities between the results obtained in this study and those from previous clinical evaluations of ribavirin against HPS, further validate the hamster model of lethal HPS and demonstrate its usefulness in screening antiviral agents against

  2. DNA vaccine-generated duck polyclonal antibodies as a postexposure prophylactic to prevent hantavirus pulmonary syndrome (HPS.

    Directory of Open Access Journals (Sweden)

    Rebecca Brocato

    Full Text Available Andes virus (ANDV is the predominant cause of hantavirus pulmonary syndrome (HPS in South America and the only hantavirus known to be transmitted person-to-person. There are no vaccines, prophylactics, or therapeutics to prevent or treat this highly pathogenic disease (case-fatality 35-40%. Infection of Syrian hamsters with ANDV results in a disease that closely mimics human HPS in incubation time, symptoms of respiratory distress, and disease pathology. Here, we evaluated the feasibility of two postexposure prophylaxis strategies in the ANDV/hamster lethal disease model. First, we evaluated a natural product, human polyclonal antibody, obtained as fresh frozen plasma (FFP from a HPS survivor. Second, we used DNA vaccine technology to manufacture a polyclonal immunoglobulin-based product that could be purified from the eggs of vaccinated ducks (Anas platyrhynchos. The natural "despeciation" of the duck IgY (i.e., Fc removed results in an immunoglobulin predicted to be minimally reactogenic in humans. Administration of ≥ 5,000 neutralizing antibody units (NAU/kg of FFP-protected hamsters from lethal disease when given up to 8 days after intranasal ANDV challenge. IgY/IgYΔFc antibodies purified from the eggs of DNA-vaccinated ducks effectively neutralized ANDV in vitro as measured by plaque reduction neutralization tests (PRNT. Administration of 12,000 NAU/kg of duck egg-derived IgY/IgYΔFc protected hamsters when administered up to 8 days after intranasal challenge and 5 days after intramuscular challenge. These experiments demonstrate that convalescent FFP shows promise as a postexposure HPS prophylactic. Moreover, these data demonstrate the feasibility of using DNA vaccine technology coupled with the duck/egg system to manufacture a product that could supplement or replace FFP. The DNA vaccine-duck/egg system can be scaled as needed and obviates the necessity of using limited blood products obtained from a small number of HPS survivors. This

  3. Microevolution of Puumala hantavirus during a complete population cycle of its host, the bank vole (Myodes glareolus.

    Directory of Open Access Journals (Sweden)

    Maria Razzauti

    Full Text Available Microevolution of Puumala hantavirus (PUUV was studied throughout a population cycle of its host, the bank vole (Myodes glareolus. We monitored PUUV variants circulating in the host population in Central Finland over a five-year period that included two peak-phases and two population declines. Of 1369 bank voles examined, 360 (26.3% were found infected with PUUV. Partial sequences of each of the three genome segments were recovered (approx. 12% of PUUV genome from 356 bank voles. Analyses of these sequences disclosed the following features of PUUV evolution: 1 nucleotide substitutions are mostly silent and deduced amino acid changes are mainly conservative, suggesting stabilizing selection at the protein level; 2 the three genome segments accumulate mutations at a different rate; 3 some of the circulating PUUV variants are frequently observed while others are transient; 4 frequently occurring PUUV variants are composed of the most abundant segment genotypes (copious and new transient variants are continually generated; 5 reassortment of PUUV genome segments occurs regularly and follows a specific pattern of segments association; 6 prevalence of reassortant variants oscillates with season and is higher in the autumn than in the spring; and 7 reassortants are transient, i.e., they are not competitively superior to their parental variants. Collectively, these observations support a quasi-neutral mode of PUUV microevolution with a steady generation of transient variants, including reassortants, and preservation of a few preferred genotypes.

  4. Energy in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-11-01

    Energy in Sweden is published annually by the Swedish Energy Agency. Energy in Sweden 2004, together with its statistics supplement, Energy in Sweden: Facts and Figures 2004, is intended to provide decision-makers, journalists and the public with a single source of easily available information on conditions and developments in the energy sector. In recent years, Swedish energy and environmental policy has been increasingly concentrated on establishing or improving the long-term conditions for efficient energy markets and efficient use of energy. Restructuring of the Swedish electricity market, greater internationalisation and the effects of the energy system on the wider environment and on climate are important factors that influence the direction of energy policy and so also development of the energy markets. The line that was started by the 2002 Energy Policy Agreement, under the name of Working Together for a Reliable, Efficient and Environmentally Aware Energy Supply (Bill no. 2001/02:143), continues. The shift in taxation policy to encourage the move towards a sustainable energy system and reduced environmental impact continues, as exemplified by the introduction of the electricity certificate system on 1st May 2003. The negotiations that were started in 2003 with a view to progressive shut-down of nuclear power generation were broken off in October 2004 without having reached agreement with the nuclear power companies. As soon as the breakdown of the negotiations was announced, the Government, together with the Left Party and the Centre Party, stated that Barsebaeck 2 will be closed in 2005. Sweden's climate policy is based on the Climate Strategy Act (Bill no. 2001/02:55), which was adopted by Parliament in March 2002. It is expected that trading in emission rights, in accordance with the EU Emissions Trading Directive, will start in January 2005, with publication of national emission rights allocations on 30th September 2004. One of the more important

  5. Energy in Sweden 2004

    International Nuclear Information System (INIS)

    2004-11-01

    Energy in Sweden is published annually by the Swedish Energy Agency. Energy in Sweden 2004, together with its statistics supplement, Energy in Sweden: Facts and Figures 2004, is intended to provide decision-makers, journalists and the public with a single source of easily available information on conditions and developments in the energy sector. In recent years, Swedish energy and environmental policy has been increasingly concentrated on establishing or improving the long-term conditions for efficient energy markets and efficient use of energy. Restructuring of the Swedish electricity market, greater internationalisation and the effects of the energy system on the wider environment and on climate are important factors that influence the direction of energy policy and so also development of the energy markets. The line that was started by the 2002 Energy Policy Agreement, under the name of Working Together for a Reliable, Efficient and Environmentally Aware Energy Supply (Bill no. 2001/02:143), continues. The shift in taxation policy to encourage the move towards a sustainable energy system and reduced environmental impact continues, as exemplified by the introduction of the electricity certificate system on 1st May 2003. The negotiations that were started in 2003 with a view to progressive shut-down of nuclear power generation were broken off in October 2004 without having reached agreement with the nuclear power companies. As soon as the breakdown of the negotiations was announced, the Government, together with the Left Party and the Centre Party, stated that Barsebaeck 2 will be closed in 2005. Sweden's climate policy is based on the Climate Strategy Act (Bill no. 2001/02:55), which was adopted by Parliament in March 2002. It is expected that trading in emission rights, in accordance with the EU Emissions Trading Directive, will start in January 2005, with publication of national emission rights allocations on 30th September 2004. One of the more important tasks

  6. Decommissioning policy in Sweden

    International Nuclear Information System (INIS)

    Bergman, C.; Boge, R.; Snihs, J.O.

    1987-01-01

    In Sweden the nuclear power program is, according to a parliamentary decision, limited to twelve power producing reactors. The last reactor shall be taken out of service no later than the year 2010. As a result of the Chernobyl accident the program for taking the reactors out of service will be accelerated. This report is the first approach by the Swedish authorities to formulate a decommissioning policy. It is not the final policy document but it discusses the principal questions from the special Swedish viewpoint. (orig.)

  7. Sweden's largest Facebook study

    OpenAIRE

    Denti, Leif; Barbopoulus, Isak; Nilsson, Ida; Holmberg, Linda; Thulin, Magdalena; Wendeblad, Malin; Andén, Lisa; Davidsson, Emelie

    2012-01-01

    The emergence of the Internet has made it easier for people to socially interact than ever before. Today, the most popular channel is Facebook with over 845 million users world wide. In Sweden, the number of users amount to approximately half of the population. We had two aims with this study. First, we investigate which areas of Facebook usage that Swedish Facebook users consider more important vis-a-vis less important. We were also interested in how users convey their persona through t... m...

  8. Decommissioning policy in Sweden

    International Nuclear Information System (INIS)

    Bergman, C.; Boge, R.; Snihs, J.O.

    1987-01-01

    In Sweden the nuclear power program is, according to a parliamentary decision, limited to twelve power producing reactors. The last reactor shall be taken out of service no later than the year 2010. As a result of the Chernobyl accident the program for taking the reactors out of service will be accelerated. The first approach by the Swedish authorities to formulate a decommissioning policy is discussed. It is not the final policy document but it discusses the principal questions from the special Swedish viewpoint

  9. Genetic analysis of Thailand hantavirus in Bandicota indica trapped in Thailand

    Directory of Open Access Journals (Sweden)

    Hugot Jean-Pierre

    2006-09-01

    Full Text Available Abstract Sixty one tissue samples from several rodent species trapped in five provinces of Thailand were examined for the presence of hantaviral markers by enzyme-immunoassay and immunoblotting. Four samples, all from the great bandicoot rat Bandicota indica, were confirmed positive for the hantaviral N-antigen. Two of them were trapped in Nakhon Pathom province, the other two in Nakhon Ratchasima province, approximately 250 km from the other trapping site. When analysed by RT-nested PCR, all four rodents were found positive for the hantaviral S- and M-segment nucleotide sequences. Genetic analysis revealed that the four newly described wild-type strains belong to Thailand hantavirus. On the phylogenetic trees they formed a well-supported cluster within the group of Murinae-associated hantaviruses and shared a recent common ancestor with Seoul virus.

  10. Hantavirus pulmonary syndrome (Rio Mamore Virus) in the Peruvian Amazon region

    OpenAIRE

    Casapía, Martín; Mamani, Enrique; García, María P; Miraval, María L; Valencia, Pedro; Quino, Alberto H; Álvarez, Carlos; Donaires, Luis F

    2012-01-01

    La hantavirosis es una infección viral zoonótica transmitida por roedores cuya forma clínica más letal es el síndrome pulmonar por Hantavirus (SPH). La variante río Mamoré es autóctona de Sudamérica y fue descrita en roedores sin asociarla a enfermedad en humanos. Se presenta dos casos de SPH causados por hantavirus río Mamoré en la Amazonía peruana en noviembre de 2011. En ambos casos, el diagnóstico confirmatorio fue molecular, efectuados en el Instituto Nacional de Salud de Perú. Se realiz...

  11. Feminist Language Planning in Sweden

    Science.gov (United States)

    Milles, Karin

    2011-01-01

    The international literature has often described linguistic authorities as being opposed to the idea of changing language in the name of feminism. However, in Sweden, many linguistic authorities have been active agents in adopting feminist language reforms. This is probably due to Sweden's long tradition of political feminist efforts and to the…

  12. Hantavirus pulmonary syndrome in Tucumán province associated to an unexpected viral genotype

    Directory of Open Access Journals (Sweden)

    Matías Ciancaglini

    2017-04-01

    Full Text Available We describe the characterization of the viral genotype involved in the first case of hantavirus pulmonary syndrome reported in Tucumán, a Northwestern province of Argentina. A 23-year-old woman, with no record of travel history and previously diagnosed with an antiphospholipid syndrome, died after 11 days of severe cardiopulmonary insufficiency. Among the four endemic regions of hantavirus pulmonary syndrome in Argentina, the Northwest Region has the highest incidence, exceeding 50% of all reported cases in the country. Until now, only Salta and Jujuy (2 out of the 6 provinces composing the Northwest Region, reported cases of hantavirus pulmonary syndrome, all of which occurred in the Yungas Forest area. Remarkably, the viral genotype characterized in this case showed higher nucleotide identity with the Andes-BsAs genotype most prevalent in Buenos Aires province, located 1400 km apart from Tucumán, than with any of the commonly found genotypes in the Northwest Region. The Andes-BsAs genotype has been associated with 30% lethality and interhuman transmission in Buenos Aires province. Interhuman transmission cannot be ruled out in the present case

  13. Laboratory-associated infections and biosafety.

    OpenAIRE

    Sewell, D L

    1995-01-01

    An estimated 500,000 laboratory workers in the United States are at risk of exposure to infectious agents that cause disease ranging from inapparent to life-threatening infections, but the precise risk to a given worker unknown. The emergence of human immunodeficiency virus and hantavirus, the continuing problem of hepatitis B virus, and the reemergence of Mycobacterium tuberculosis have renewed interest in biosafety for the employees of laboratories and health care facilities. This review ex...

  14. Acidification research in Sweden

    International Nuclear Information System (INIS)

    Staaf, H.; Bertills, U.

    1992-01-01

    A number of acid rain research programmes have been conducted in Sweden since 1978. The total cost for these programmes has amounted to about 250 million SEK, and during this period an additional 950 million SEK has been used to finance practical countermeasures, mainly lake liming. Acid deposition has caused damage to soil, lakes, groundwater, flora and fauna, buildings and materials. The role of acid rain in causing forest damage is not yet fully elucidated. However, there is strong evidence suggesting that ongoing soil acidification and nutrient imbalances associated with it pose the major threat to Swedish forests. Current ozone levels are damaging trees on the physiological level, but the effects of ozone on forest production in unknown. Liming is an efficient means of counteracting the negative effects of acidic deposition on forest soil, lakes and watercourses. 8 refs., 6 figs., 1 tab

  15. Radwaste management in Sweden

    International Nuclear Information System (INIS)

    Ahlstroem, P.E.; Ungermark, S.

    1987-01-01

    The waste management system planned for handling the radioactive residues from Sweden's 12 nuclear power units is based on the operation of all the units up to the year 2010 in accordance with Parliament's decision to abolish nuclear power by that time. The main strategy for handling spent nuclear fuel is direct disposal without reprocessing. In the design of the radwaste management system the following fundamental principles have been applied. Short-lived waste will be disposed of as soon as possible after it has been generated. Spent fuel will be intermediately stored for about 40 years before final disposal, thereby reducing heat generation in the repository. Other long-lived waste will be disposed of jointly with the final disposal of spent fuel. 3 figs., 1 tab

  16. Temporal Analysis of Andes Virus and Sin Nombre Virus Infections of Syrian Hamsters

    Science.gov (United States)

    2007-05-01

    Microbiology . All Rights Reserved. Temporal Analysis of Andes Virus and Sin Nombre Virus Infections of Syrian Hamsters Victoria Wahl-Jensen,1 Jennifer...Ye, C., J. Prescott , R. Nofchissey, D. Goade, and B. Hjelle. 2004. Neutralizing antibodies and Sin Nombre virus RNA after recovery from hantavirus

  17. Gene S characterization of Hantavirus species Seoul virus isolated from Rattus norvegicuson an Indonesian island

    Directory of Open Access Journals (Sweden)

    Dian Perwitasari

    2014-08-01

    Full Text Available AbstrakLatar belakang: Hantavirus hidup dan berkembang biak di tubuh hewan pengerat, salah satunya Rattus norvegicus yang banyak ditemukan di daerah kepulauan di Indonesia. Hantavirus spesies Seoul virus (SEOV adalah virus RNA negatif rantai tunggal yang termasuk dalam keluarga Bunyaviridae, mempunyai beberapa gen spesifik terutama gen S yang dapat dikembangkan untuk uji diagnostik. Tujuan penelitian ini ialah untuk mengetahui karakter dari gen S dari Hantavirus spesies Seoulvirus.Metode:Pada penelitian ini dilakukan sekuensing gen S yang berasal dari jaringan paru-paru rodensia.  Fragmen DNA yang disekuensing menggunakan primer DNA SEOS-28F danSEOS -360R,VNS-1501F dan VNS-CSR. Hasil sekuensing dianalisis menggunakan program seqscapedan dianalisis menggunakan program Bioedit dan Mega5. Analisis filogenetik untuk homologi nukleotida dan asam amino dari ketiga strain Kepulauan Seribu tersebut dibandingkan dengan spesies hantavirus lainnya yang diambil dari genebank. Hasil:Analisis Homologi nukleotida dan asam amino antara strain Kepulauan Seribu dengan SEOV menunjukkan homologi nukleotida tertinggi pada strain KS74 (88,4% dan terendah pada KS90 (87,2%, sedangkan homologi asam amino tertinggi adalah strain KS74 (91.3% dan terendah pada strain KS90 (89,5%. Kesimpulan:Karakter gen S virus yang ditemukan di Kepulauan Seribu sebanding dengan virus SEOV yang ditemukan di Singapura dan Korea.  (Health Science Indones 2014;1:1-6Kata kunci:Seoul virus, gen S, Kepulauan Seribu, IndonesiaAbstractBackground: Hantavirus lives and reproduces in the body of rodents. Rattus norvegicuswas one found in the Kepulauan Seribu islands of Indonesia. Hantavirus species Seoul virus (SEOV is a negative single chain RNA viruses included in the family Bunyaviridae. It has a few specific genes, especially genes S that can be developed for a diagnostic test. The aim of this study was to ascertain the character of gene S of hantavirus species Seoul virus. Methods: Gene

  18. Hamster-Adapted Sin Nombre Virus Causes Disseminated Infection and Efficiently Replicates in Pulmonary Endothelial Cells without Signs of Disease

    OpenAIRE

    Safronetz, David; Prescott, Joseph; Haddock, Elaine; Scott, Dana P.; Feldmann, Heinz; Ebihara, Hideki

    2013-01-01

    To date, a laboratory animal model for the study of Sin Nombre virus (SNV) infection or associated disease has not been described. Unlike infection with Andes virus, which causes lethal hantavirus pulmonary syndrome (HPS)-like disease in hamsters, SNV infection is short-lived, with no viremia and little dissemination. Here we investigated the effect of passaging SNV in hamsters. We found that a host-adapted SNV achieves prolonged and disseminated infection in hamsters, including efficient rep...

  19. Neutron Powder Diffraction in Sweden

    International Nuclear Information System (INIS)

    Tellgren, R.

    1986-01-01

    Neutron powder diffraction in Sweden has developed around the research reactor R2 in Studsvik. The article describes this facility and presents a historical review of research results obtained. It also gives some ideas of plans for future development

  20. Landscape Epidemiology of Tularemia Outbreaks in Sweden

    Science.gov (United States)

    Svensson, Kerstin; Bäck, Erik; Eliasson, Henrik; Berglund, Lennart; Granberg, Malin; Karlsson, Linda; Larsson, Pär; Forsman, Mats

    2009-01-01

    Summer outbreaks of tularemia that occurred from 1995 through 2005 in 2 locations in Sweden affected 441 persons. We performed an epidemiologic investigation of these outbreaks using a novel strategy, involving high-resolution genotyping of Francisella tularensis isolates obtained from 136 patients (using 18 genetic markers developed from 6 F. tularensis genome sequences) and interviews with the patients. Strong spatial associations were found between F. tularensis subpopulations and the places of disease transmission; infection by some subpopulations occurred within areas as small as 2 km2, indicating unidentified environmental point sources of tularemia. In both locations, disease clusters were associated with recreational areas beside water, and genetic subpopulations were present throughout the tularemia season and persisted over years. High-resolution genotyping in combination with patients’ statements about geographic places of disease transmission provided valuable indications of likely sources of infection and the causal genotypes during these tularemia outbreaks. PMID:19961673

  1. Spatial and Temporal Epidemiology of Nephropathia Epidemica Incidence and Hantavirus Seroprevalence in Rodent Hosts: Identification of the Main Environmental Factors in Europe.

    Science.gov (United States)

    Monchatre-Leroy, E; Crespin, L; Boué, F; Marianneau, P; Calavas, D; Hénaux, V

    2017-08-01

    In Europe, the increasing number of nephropathia epidemica (NE) infections in humans, caused by Puumala virus carried by bank voles (Myodes glareolus), has triggered studies of environmental factors driving these infections. NE infections have been shown to occur in specific geographical areas characterized by environmental factors that influence the distribution and dynamics of host populations and virus persistence in the soil. Here, we review the influence of environmental conditions (including climate factors, food availability and habitat conditions) with respect to incidence in humans and seroprevalence in rodents, considering both direct and indirect transmission pathways. For each type of environmental factor, results and discrepancies between studies are presented and examined in the light of biological hypotheses. Overall, food availability and temperature appear to be the main drivers of host seroprevalence and NE incidence, but data quality and statistical approaches varied greatly among studies. We highlight the issues that now need to be addressed and suggest improvements for study design in regard to the current knowledge on hantavirus epidemiology. © 2016 Blackwell Verlag GmbH.

  2. Conversion program in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Jonsson, E.B. [Studsvik Nuclear AB, Nykoeping (Sweden)

    1997-08-01

    The conversion of the Swedish 50 MW R2 reactor from HEU to LEU fuel has been successfully accomplished over a 16 cycles long process. The conversion started in January 1991 with the introduction of 6 LEU assemblies in the 8*8 core. The first all LEU core was loaded in March 1993 and physics measurements were performed for the final licensing reports. A total of 142 LEU fuel assemblies have been irradiated up until September 1994 without any fuel incident. The operating licence for the R2 reactor was renewed in mid 1994 taking into account new fuel type. The Swedish Nuclear Inspectorate (SKI) pointed out one crucial problem with the LEU operation, that the back end of the LEU fuel cycle has not yet been solved. For the HEU fuel Sweden had the reprocessing alternative. The country is now relying heavily on the success of the USDOEs Off Site Fuels Policy to take back the spent fuel from the research reactors. They have in the meantime increased their intermediate storage facilities. There is, however, a limit both in time and space for storage of MTR-type of assemblies in water. The penalty of the lower thermal neutron flux in LEU cores has been reduced by improvements of the new irradiation rigs and by fine tuning the core calculations. The Studsvik code package, CASMO-SIMULATE, widely used for ICFM in LWRs has been modified to suit the compact MTR type of core.

  3. Uranium production in Sweden

    International Nuclear Information System (INIS)

    Bergh, S.

    1994-01-01

    The history of uranium production in Sweden is reviewed in the article. The World War II led to an exploitation of the Swedish alum shale on a large scale. In the last phase of the war it also became obvious that the shale might be used for energy production of quite another kind than oil. In 1947 AB Atom energy was founded, an enterprise with one of its purposes to extract uranium for peaceful use. A plant with a yearly capacity of 120 tons of uranium was erected at Ranstad and ready for production by 1965. From the start in Ranstad and for many years to come there was hardly any interest in an immediate large uranium production. It was decided to use the plant for studies on its more effective exploitation in case of an expansion in the future, bearing in mind the reactor programme. In the course of time economical reasons began to speak against the project. The shale seemed to have a future neither as oil nor as uranium resource. The complete termination of the work on uranium production from shale occurred in 1989

  4. Dieselization in Sweden

    International Nuclear Information System (INIS)

    Kågeson, Per

    2013-01-01

    In Sweden the market share of diesel cars grew from below 10 per cent in 2005 to 62 per cent in 2011 despite a closing gap between pump prices on diesel oil and gasoline, and diesel cars being less favored than ethanol and biogas cars in terms of tax cuts and other subsidies offered to “environment cars”. The most important factor behind the dieselization was probably the market entrance of a number of low-consuming models. Towards the end of the period a growing number of diesel models were able to meet the 120 g CO 2 threshold applicable to “environment cars” that cannot use ethanol or biogas. This helped such models increase their share of the diesel car market from zero to 41 per cent. Dieselization appears to have had only a minor effect on annual distances driven. The higher average annual mileage of diesel cars is probably to a large extent a result of a self-selection bias. However, the Swedish diesel car fleet is young, and the direct rebound effect stemming from a lower variable driving cost may show up more clearly as the fleet gets older based on the assumption that second owners are more fuel price sensitive than first owners. - Highlights: ► This paper tries to explain the fast dieselization of the new Swedish car fleet. ► It identifies changes in supply and the impact of tax benefits. ► Finally it studies the impact on the annual average mileage

  5. Nuclear power in Sweden

    International Nuclear Information System (INIS)

    Wikdahl, C.E.

    1999-01-01

    Sweden uses 16,000 kWh of electricity per person, by far the highest consumption in EU. The reason is a well-developed electricity intensive industry and a cold climate with high share of electric heating. The annual power consumption has for several years been about 140 TWh and a normal year almost 50 per cent is produced by hydro and 50 percent by nuclear. A new legislation, giving the Government the right to ordering the closure nuclear power plants of political reasons without any reference to safety, has been accepted by the Parliament. The new act, in force since January 1, 1998, is a specially tailored expropriation act. Certain rules for the economical compensation to the owner of a plant to be closed are defined in the new act. The common view in the Swedish industry is that the energy conservation methods proposed by the Government are unrealistic. During the first period of about five years the import from coal fired plants in Denmark and Germany is the only realistic alternative. Later natural gas combi units and new bioenergy plants for co-production of heat and power (CHP) might be available. (orig.) [de

  6. Estimating Hantavirus Risk in Southern Argentina: A GIS-Based Approach Combining Human Cases and Host Distribution

    Science.gov (United States)

    Andreo, Veronica; Neteler, Markus; Rocchini, Duccio; Provensal, Cecilia; Levis, Silvana; Porcasi, Ximena; Rizzoli, Annapaola; Lanfri, Mario; Scavuzzo, Marcelo; Pini, Noemi; Enria, Delia; Polop, Jaime

    2014-01-01

    We use a Species Distribution Modeling (SDM) approach along with Geographic Information Systems (GIS) techniques to examine the potential distribution of hantavirus pulmonary syndrome (HPS) caused by Andes virus (ANDV) in southern Argentina and, more precisely, define and estimate the area with the highest infection probability for humans, through the combination with the distribution map for the competent rodent host (Oligoryzomys longicaudatus). Sites with confirmed cases of HPS in the period 1995–2009 were mostly concentrated in a narrow strip (~90 km × 900 km) along the Andes range from northern Neuquén to central Chubut province. This area is characterized by high mean annual precipitation (~1,000 mm on average), but dry summers (less than 100 mm), very low percentages of bare soil (~10% on average) and low temperatures in the coldest month (minimum average temperature −1.5 °C), as compared to the HPS-free areas, features that coincide with sub-Antarctic forests and shrublands (especially those dominated by the invasive plant Rosa rubiginosa), where rodent host abundances and ANDV prevalences are known to be the highest. Through the combination of predictive distribution maps of the reservoir host and disease cases, we found that the area with the highest probability for HPS to occur overlaps only 28% with the most suitable habitat for O. longicaudatus. With this approach, we made a step forward in the understanding of the risk factors that need to be considered in the forecasting and mapping of risk at the regional/national scale. We propose the implementation and use of thematic maps, such as the one built here, as a basic tool allowing public health authorities to focus surveillance efforts and normally scarce resources for prevention and control actions in vast areas like southern Argentina. PMID:24424500

  7. Estimating Hantavirus Risk in Southern Argentina: A GIS-Based Approach Combining Human Cases and Host Distribution

    Directory of Open Access Journals (Sweden)

    Veronica Andreo

    2014-01-01

    Full Text Available We use a Species Distribution Modeling (SDM approach along with Geographic Information Systems (GIS techniques to examine the potential distribution of hantavirus pulmonary syndrome (HPS caused by Andes virus (ANDV in southern Argentina and, more precisely, define and estimate the area with the highest infection probability for humans, through the combination with the distribution map for the competent rodent host (Oligoryzomys longicaudatus. Sites with confirmed cases of HPS in the period 1995–2009 were mostly concentrated in a narrow strip (~90 km × 900 km along the Andes range from northern Neuquén to central Chubut province. This area is characterized by high mean annual precipitation (~1,000 mm on average, but dry summers (less than 100 mm, very low percentages of bare soil (~10% on average and low temperatures in the coldest month (minimum average temperature −1.5 °C, as compared to the HPS-free areas, features that coincide with sub-Antarctic forests and shrublands (especially those dominated by the invasive plant Rosa rubiginosa, where rodent host abundances and ANDV prevalences are known to be the highest. Through the combination of predictive distribution maps of the reservoir host and disease cases, we found that the area with the highest probability for HPS to occur overlaps only 28% with the most suitable habitat for O. longicaudatus. With this approach, we made a step forward in the understanding of the risk factors that need to be considered in the forecasting and mapping of risk at the regional/national scale. We propose the implementation and use of thematic maps, such as the one built here, as a basic tool allowing public health authorities to focus surveillance efforts and normally scarce resources for prevention and control actions in vast areas like southern Argentina.

  8. Spatial and temporal patterns of human Puumala virus (PUUV infections in Germany

    Directory of Open Access Journals (Sweden)

    Sarah Cunze

    2018-02-01

    Full Text Available Background Worldwide, the number of recorded human hantavirus infections as well as the number of affected countries is on the rise. In Europe, most human hantavirus infections are caused by the Puumala virus (PUUV, with bank voles (Myodes glareolus as reservoir hosts. Generally, infection outbreaks have been related to environmental conditions, particularly climatic conditions, food supply for the reservoir species and land use. However, although attempts have been made, the insufficient availability of environmental data is often hampering accurate temporal and spatially explicit models of human hantavirus infections. Methods In the present study, dynamics of human PUUV infections between 2001 and 2015 were explored using ArcGIS in order to identify spatio-temporal patterns. Results Percentage cover of forest area was identified as an important factor for the spatial pattern, whereas beech mast was found explaining temporal patterns of human PUUV infections in Germany. High numbers of infections were recorded in 2007, 2010 and 2012 and areas with highest records were located in Baden-Wuerttemberg (southwest Germany and North Rhine-Westphalia (western Germany. Conclusion More reliable data on reservoir host distribution, pathogen verification as well as an increased awareness of physicians are some of the factors that should improve future human infection risk assessments in Germany.

  9. Women and energy in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Rising, Agneta [Vattenfall - Swedish State Power Board (Sweden)

    1989-07-01

    Sweden is currently facing a new situation In energy politics. Nuclear power is to be phased out nd replaced by new energy sources and by more effective use of electricity. This will be a great change for the whole society as nuclear power today is giving half of electricity. And Sweden is a high-consumption- country, in fact looking at the top list of electricity consumption per capita in the world, you will find Sweden on the fourth plate. In general- women know less than men about the relation between energy, technology, environment and economy. This knowledge is required If women re to Influence the choice of future energy supplies of Sweden. It is with this background the project 'Women and Energy' has been started. Important decisions are to be made within their fairly immediate future with major consequences for Sweden's coming development. These decisions have until now often been made by men, but now it Is the hope of Vattenfall that women will be able to influence these decisions. So that all of 'nuclear people' may share responsibility the path that has been chosen.

  10. Women and energy in Sweden

    International Nuclear Information System (INIS)

    Rising, Agneta

    1989-01-01

    Sweden is currently facing a new situation In energy politics. Nuclear power is to be phased out nd replaced by new energy sources and by more effective use of electricity. This will be a great change for the whole society as nuclear power today is giving half of electricity. And Sweden is a high-consumption- country, in fact looking at the top list of electricity consumption per capita in the world, you will find Sweden on the fourth plate. In general- women know less than men about the relation between energy, technology, environment and economy. This knowledge is required If women re to Influence the choice of future energy supplies of Sweden. It is with this background the project 'Women and Energy' has been started. Important decisions are to be made within their fairly immediate future with major consequences for Sweden's coming development. These decisions have until now often been made by men, but now it Is the hope of Vattenfall that women will be able to influence these decisions. So that all of 'nuclear people' may share responsibility the path that has been chosen

  11. Diagnóstico virológico y molecular de virus transmitidos por roedores. Hantavirus y arenavirus

    Directory of Open Access Journals (Sweden)

    Silvana Levis

    2010-04-01

    Full Text Available Los hantavirus (familia Bunyaviridae y arenavirus (familia Arenaviridae son virus de roedores; cada uno de ellos parece estar estrictamente asociado con una especie de roedor en la que causa una infección persistente y asintomática. En las Américas tienen como reservorios primarios a roedores de la sub-familia Sigmodontinae, y son causantes de síndrome pulmonar por Hantavirus (SPH y fiebres hemorrágicas, respectivamente (1,2. El número de estos virus identificados en los últimos años ha aumentado significativamente; actualmente, el género Hantavirus está compuesto por más de 28 tipos diferentes, mientras que al menos 23 arenavirus conforman el género Arenavirus. Entre los hantavirus asociados con SPH se destacan el virus Sin Nombre en Norteamérica, y los virus Andes, Laguna Negra, Caño Delgadito, Araraquara y Juquitiba, en el cono sur de América, entre otros (2. Los arenavirus asociados a fiebres hemorrágicas reconocidos en Sud América al presente son: Junín (Argentina, Guanarito (Venezuela, Sabiá (Brasil, y Machupo y Chapare (Bolivia (3.

  12. More Novel Hantaviruses and Diversifying Reservoir Hosts — Time for Development of Reservoir-Derived Cell Culture Models?

    Directory of Open Access Journals (Sweden)

    Isabella Eckerle

    2014-02-01

    Full Text Available Due to novel, improved and high-throughput detection methods, there is a plethora of newly identified viruses within the genus Hantavirus. Furthermore, reservoir host species are increasingly recognized besides representatives of the order Rodentia, now including members of the mammalian orders Soricomorpha/Eulipotyphla and Chiroptera. Despite the great interest created by emerging zoonotic viruses, there is still a gross lack of in vitro models, which reflect the exclusive host adaptation of most zoonotic viruses. The usually narrow host range and genetic diversity of hantaviruses make them an exciting candidate for studying virus-host interactions on a cellular level. To do so, well-characterized reservoir cell lines covering a wide range of bat, insectivore and rodent species are essential. Most currently available cell culture models display a heterologous virus-host relationship and are therefore only of limited value. Here, we review the recently established approaches to generate reservoir-derived cell culture models for the in vitro study of virus-host interactions. These successfully used model systems almost exclusively originate from bats and bat-borne viruses other than hantaviruses. Therefore we propose a parallel approach for research on rodent- and insectivore-borne hantaviruses, taking the generation of novel rodent and insectivore cell lines from wildlife species into account. These cell lines would be also valuable for studies on further rodent-borne viruses, such as orthopox- and arenaviruses.

  13. Complete genome characterisation and phylogenetic position of Tigray hantavirus from the Ethiopian white-footed mouse, Stenocephalemys albipes

    Czech Academy of Sciences Publication Activity Database

    Goüy de Bellocq, Joëlle; Těšíková, Jana; Meheretu, Y.; Čížková, Dagmar; Bryjová, Anna; Leirs, H.; Bryja, Josef

    2016-01-01

    Roč. 45, November (2016), s. 242-245 ISSN 1567-1348 R&D Projects: GA ČR GCP502/11/J070 Institutional support: RVO:68081766 Keywords : Hantavirus * Murinae * Ethiopia * High throughput sequencing * Genomics Subject RIV: EE - Microbiology, Virology Impact factor: 2.885, year: 2016

  14. Dobrava-Belgrade hantavirus from Germany shows receptor usage and innate immunity induction consistent with the pathogenicity of the virus in humans.

    Directory of Open Access Journals (Sweden)

    Elena Popugaeva

    Full Text Available BACKGROUND: Dobrava-Belgrade virus (DOBV is a European hantavirus causing hemorrhagic fever with renal syndrome (HFRS in humans with fatality rates of up to 12%. DOBV-associated clinical cases typically occur also in the northern part of Germany where the virus is carried by the striped field mouse (Apodemus agrarius. However, the causative agent responsible for human illness has not been previously isolated. METHODOLOGY/PRINCIPAL FINDINGS: Here we report on characterization of a novel cell culture isolate from Germany obtained from a lung tissue of "spillover" infected yellow necked mouse (A. flavicollis trapped near the city of Greifswald. Phylogenetic analyses demonstrated close clustering of the new strain, designated Greifswald/Aa (GRW/Aa with the nucleotide sequence obtained from a northern German HFRS patient. The virus was effectively blocked by specific antibodies directed against β3 integrins and Decay Accelerating Factor (DAF indicating that the virus uses same receptors as the highly pathogenic Hantaan virus (HTNV. In addition, activation of selected innate immunity markers as interferon β and λ and antiviral protein MxA after viral infection of A549 cells was investigated and showed that the virus modulates the first-line antiviral response in a similar way as HTNV. CONCLUSIONS/SIGNIFICANCE: In summary, our study reveals novel data on DOBV receptor usage and innate immunity induction in relationship to virus pathogenicity and underlines the potency of German DOBV strains to act as human pathogen.

  15. Landscape genetics highlights the role of bank vole metapopulation dynamics in the epidemiology of Puumala hantavirus.

    Science.gov (United States)

    Guivier, E; Galan, M; Chaval, Y; Xuéreb, A; Ribas Salvador, A; Poulle, M-L; Voutilainen, L; Henttonen, H; Charbonnel, N; Cosson, J F

    2011-09-01

    Rodent host dynamics and dispersal are thought to be critical for hantavirus epidemiology as they determine pathogen persistence and transmission within and between host populations. We used landscape genetics to investigate how the population dynamics of the bank vole Myodes glareolus, the host of Puumala hantavirus (PUUV), vary with forest fragmentation and influence PUUV epidemiology. We sampled vole populations within the Ardennes, a French PUUV endemic area. We inferred demographic features such as population size, isolation and migration with regard to landscape configuration. We next analysed the influence of M. glareolus population dynamics on PUUV spatial distribution. Our results revealed that the global metapopulation dynamics of bank voles were strongly shaped by landscape features, including suitable patch size and connectivity. Large effective size in forest might therefore contribute to the higher observed levels of PUUV prevalence. By contrast, populations from hedge networks highly suffered from genetic drift and appeared strongly isolated from all other populations. This might result in high probabilities of local extinction for both M. glareolus and PUUV. Besides, we detected signatures of asymmetric bank vole migration from forests to hedges. These movements were likely to sustain PUUV in fragmented landscapes. In conclusion, our study provided arguments in favour of source-sink dynamics shaping PUUV persistence and spread in heterogeneous, Western European temperate landscapes. It illustrated the potential contribution of landscape genetics to the understanding of the epidemiological processes occurring at this local scale. © 2011 Blackwell Publishing Ltd.

  16. Policies promoting Biofuels in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Holmgren, Kristina [IVL Swedish Environmental Research Inst., Goeteborg (Sweden); Chalmers Univ. of Technology, Div. of Heat and Power Technology., Goeteborg (Sweden)

    2012-07-01

    This report was written as part of a course in Environmental Economics and Policy Instruments at the University of Gothenburg. It aims at summarizing the policy instruments introduced to directly affect the production and use of biofuels in Sweden. Since Sweden is part of the EU also EU policies were included. There are additional policy instruments which affect the production and utilization of biofuels in a more indirect way that are not presented here. The economic analysis in this paper is limited and could be developed from the information presented in order to draw further conclusions on necessary changes in order to reach set targets.

  17. Child Care in Sweden. Fact Sheets on Sweden.

    Science.gov (United States)

    Swedish Inst., Stockholm.

    This fact sheet outlines Sweden's policies of government-supported child care and parental insurance provisions. Swedish families receive: (1) free maternity and child health care; (2) child allowances for each child of 9,000 krona per year through age 16; (3) up to 450 days of paid parental leave for the birth of a child, with 360 days paid at 90…

  18. English Language Teaching Profile: Sweden.

    Science.gov (United States)

    British Council, London (England). English-Teaching Information Centre.

    This profile in outline form of the English language teaching situation in Sweden discusses the role of English within Swedish society and within the Swedish educational system. The status of English as the principal foreign language since 1945 for use in business, the media and tourism is pointed out. The system of English instruction in the…

  19. Foreign Language Learning in Sweden.

    Science.gov (United States)

    Orpet, Brian R.

    1984-01-01

    Describes a visit made to Sweden to ascertain why Swedish citizens speak such excellent English. Motivation was a key factor. Describes observations of the methods of teaching English as a second language in Swedish schools. Makes recommendations for foreign language teaching in Great Britain based on these observations. (SED)

  20. The energy transition in Sweden

    International Nuclear Information System (INIS)

    Cruciani, Michel

    2016-06-01

    Sweden has the distinction of having started several major changes to its energy supply at an early stage. The country has no fossil reserves, and so was importing increasing volumes of oil products in the years following World War II. Yet it rapidly perceived the geopolitical risks generated by such oil dependency, and so developed its nuclear capacity, enabling it to reduce quickly the role of oil in its economy after the shocks of the 1970's. Sweden has also managed to exploit its natural resources. Until the 2000's, hydropower was able to enter the market without public assistance. By contrast, wood could not have gained its current market share without a policy combining public aid for investment and penalties for competing energies. The severe economic crisis which hit the country between 1991 and 1993 led such penalties being converted into taxes, notably a tax on CO_2 emissions that came into force in 1991. This helped Sweden reconstruct its tax system, to finance its social model. The challenge highlighted the country's ability to generate consensus policy guidelines. One of these guidelines was to react immediately after initial warnings about climate change. Sweden first strengthened its energy efficiency policy, structuring field actions through a national agency backed up by partner organizations in local communities to help consumers - individuals or industries - technically and economically. Sweden then adopted an unusual instrument to promote renewable electricity, namely its system of green certificates. Implemented in 2003, this system has spurred the development of the cheapest sources of renewable energy, two-thirds coming from onshore wind and one third from biomass. The cost of this support still remains remarkably moderate today. At the end of 2014, Sweden thus only used fossil fuels to provide 30% of its primary energy supplies, while renewables accounted for 52% of final energy consumption. Energy consumption per capita remains high, but

  1. Diferencias regionales y Síndrome Pulmonar por Hantavirus (enfermedad emergente y tropical en Argentina Regional differences and Hantavirus pulmonary syndrome (an emerging and tropical disease in Argentina

    Directory of Open Access Journals (Sweden)

    Sergio Sosa-Estani

    2001-01-01

    Full Text Available Se describen algunos factores que habrían favorecido a caracterizar la expresión del Síndrome Pulmonar por Hantavirus en Argentina. Estos factores muestran diversos orígenes que van desde los procesos de ocupación del espacio y de producción, la estructura laboral, el patrón de migración humana, la etnia, la dinámica de reservorios y su relación con los tipos de virus, y el comportamiento del hombre. Estos factores se expresan en tres marcos ecológicos asociados a diferentes regiones geográficas de Argentina: 1 Noroeste, 2 Central (Pampa húmeda y 3 Sur Andina. Este complejo escenario obliga a abordar con la misma complejidad las investigaciones, para identificar determinantes primarios, biológicos, sociales y ambientales, causales de salud o enfermedad en su estrecha interacción y no individualmente. Este abordaje permitirá diseñar estrategias apropiadas para mejorar las condiciones de salud. Las mismas deberían ser diseñadas y transferidas por equipos transdisciplinarios de investigación, donde la participación de la comunidad desde las primeras etapas de desarrollo es esencial para la sustentabilidad de la estrategia.Factors related to the characteristics of Hantavirus pulmonary syndrome in Argentina are described. Factors from different scientific fields converge to form the syndrome's analytical framework. Some of these factors are the history of spatial occupation, work and production structures, human migration patterns, ethnic composition, reservoir dynamics and its relationship to the different circulating viruses, and human behavior. Furthermore, the multiple factors are expressed in three ecological frameworks, associated with three different geographical regions of Argentina: 1 Northwest; 2 Central ("wet Pampa"; and 3 South Andean. In order to understand the actual causality of health or disease as an interaction of many factors, research on the primary biological, social, and environmental determinants of

  2. Differences between Human and Rodent Plasmacytoid Dendritic Cells May Explain the Pathogenic Disparity of Hantavirus Infection

    Science.gov (United States)

    2016-06-01

    temp with blocking buffer (5% non- fat dry milk in PBS, pH 7.4 and 0.5% Tween 20). Membranes were then washed three times in washing buffer (PBS pH...per chip. To maximize high-quality alignments for read alignment, gene identification, and quantification, the raw sequence reads were trimmed to...involve virus-induced hyperinflammatory immune responses. Thrombospondin-1 (THBS1) is a large homotrimeric protein that plays a putative role in

  3. The major cellular sterol regulatory pathway is required for Andes virus infection.

    Directory of Open Access Journals (Sweden)

    Josiah Petersen

    2014-02-01

    Full Text Available The Bunyaviridae comprise a large family of RNA viruses with worldwide distribution and includes the pathogenic New World hantavirus, Andes virus (ANDV. Host factors needed for hantavirus entry remain largely enigmatic and therapeutics are unavailable. To identify cellular requirements for ANDV infection, we performed two parallel genetic screens. Analysis of a large library of insertionally mutagenized human haploid cells and a siRNA genomic screen converged on components (SREBP-2, SCAP, S1P and S2P of the sterol regulatory pathway as critically important for infection by ANDV. The significance of this pathway was confirmed using functionally deficient cells, TALEN-mediated gene disruption, RNA interference and pharmacologic inhibition. Disruption of sterol regulatory complex function impaired ANDV internalization without affecting virus binding. Pharmacologic manipulation of cholesterol levels demonstrated that ANDV entry is sensitive to changes in cellular cholesterol and raises the possibility that clinically approved regulators of sterol synthesis may prove useful for combating ANDV infection.

  4. Infection,

    Science.gov (United States)

    1980-10-16

    characteristic in severe gram-negative sepsis. Hypertriglyceridemia results from an increase in hepatic synthesis in combination with diminished activity of...induced stress, and tissue repair (1). The magnitude and type of nutritional losses caused by an infection reflect both the severity and duration of an... several functional forms of nutrient loss must be anticipated. Functional losses are defined as the within-body losses of nutrients due to infection

  5. High-resolution computed tomography findings in eight patients with hantavirus pulmonary syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Barbosa, Diego de Lacerda; Hochhegger, Bruno; Souza Junior, Arthur Soares; Zanetti, Glaucia; Escuissato, Dante Luiz; Meirelles, Gustavo de Souza Portes; Funari, Marcelo Buarque de Gusmao; Marchiori, Edson, E-mail: edmarchiori@gmail.com [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ (Brazil); Santa Casa de Porto Alegre, Porto Alegre, RS (Brazil); Faculdade de Medicina de Sao Jose do Rio Preto (FAMERP), SP (Brazil); Ultra X, Sao Jose do Rio Preto, SP (Brazil); Universidade Federal do Parana (UFPR), Curitiba, PR (Brazil); Universidade Federal de Sao Paulo (UNIFESP), Sao Paulo, SP (Brazil); Grupo Fleury, Sao Paulo, SP (Brazil); Universidade de Sao Paulo (FM/USP), Sao Paulo, SP (Brazil). Faculdade de Medicina

    2017-05-15

    Objective: The purpose of this study was to describe the high-resolution computed tomography (HRCT) findings in patients with hantavirus pulmonary syndrome (HPS). Materials and Methods: We retrospectively reviewed HRCT findings from eight cases of HPS. All patients were men, aged 19-70 (mean, 41.7) years. Diagnoses were established by serological test (enzyme-linked immunosorbent assay) in all patients. Two chest radiologists analyzed the images and reached decisions by consensus. Results: The predominant HRCT findings were ground-glass opacities (GGOs) and smooth inter- and intralobular septal thickening, found in all eight cases; however, the crazy-paving pattern was found in only three cases. Pleural effusion and peribronchovascular thickening were observed in five patients. The abnormalities were bilateral in all patients. Conclusion: The predominant HRCT findings in patients with HPS were GGOs and smooth inter- and intralobular septal thickening, which probably correlate with the histopathologic findings of pulmonary edema. (author)

  6. Drotrecogin Alpha (Activated in Two Patients with the Hantavirus Cardiopulmonary Syndrome

    Directory of Open Access Journals (Sweden)

    Robert C McDermid

    2006-01-01

    Full Text Available Hantavirus cardiopulmonary syndrome (HCPS is associated with rapid cardiopulmonary collapse from endothelial injury, resulting in massive capillary leak, shock and severe hypoxemic respiratory failure. To date, treatment remains supportive and includes mechanical ventilation, vasopressors and extracorporeal membrane oxygenation, with mortality approaching 50%. Two HCPS survivors initially given drotrecogin alpha (activated (DAA for presumed bacterial septic shock are described. Vasoactive medications were required for a maximum of 52 h, whereas creatinine levels and platelet counts normalized within seven to nine days. Given the similar presentations of HCPS and bacterial septic shock, empirical DAA therapy will likely be initiated before a definitive diagnosis of HCPS is made. Further observations of DAA in HCPS seem warranted.

  7. High-resolution computed tomography findings in eight patients with hantavirus pulmonary syndrome

    International Nuclear Information System (INIS)

    Barbosa, Diego de Lacerda; Hochhegger, Bruno; Souza Junior, Arthur Soares; Zanetti, Glaucia; Escuissato, Dante Luiz; Meirelles, Gustavo de Souza Portes; Funari, Marcelo Buarque de Gusmao; Marchiori, Edson; Santa Casa de Porto Alegre, Porto Alegre, RS; Faculdade de Medicina de Sao Jose do Rio Preto; Ultra X, Sao Jose do Rio Preto, SP; Universidade Federal do Parana; Universidade Federal de Sao Paulo; Grupo Fleury, Sao Paulo, SP; Universidade de Sao Paulo

    2017-01-01

    Objective: The purpose of this study was to describe the high-resolution computed tomography (HRCT) findings in patients with hantavirus pulmonary syndrome (HPS). Materials and Methods: We retrospectively reviewed HRCT findings from eight cases of HPS. All patients were men, aged 19-70 (mean, 41.7) years. Diagnoses were established by serological test (enzyme-linked immunosorbent assay) in all patients. Two chest radiologists analyzed the images and reached decisions by consensus. Results: The predominant HRCT findings were ground-glass opacities (GGOs) and smooth inter- and intralobular septal thickening, found in all eight cases; however, the crazy-paving pattern was found in only three cases. Pleural effusion and peribronchovascular thickening were observed in five patients. The abnormalities were bilateral in all patients. Conclusion: The predominant HRCT findings in patients with HPS were GGOs and smooth inter- and intralobular septal thickening, which probably correlate with the histopathologic findings of pulmonary edema. (author)

  8. Síndrome pulmonar e cardiovascular por hantavírus Hantavirus pulmonary and cardiovascular syndrome

    Directory of Open Access Journals (Sweden)

    Mariangela Pimentel Pincelli

    2003-10-01

    Full Text Available A síndrome pulmonar e cardiovascular por hantavírus é uma doença de conhecimento relativamente recente e freqüentemente fatal, apresentando-se como síndrome do desconforto respiratório agudo. No Brasil, desde o primeiro surto, relatado em novembro/dezembro de 1993, em Juquitiba, 226 casos já foram registrados pela Fundação Nacional da Saúde. A doença afeta indivíduos previamente hígidos, apresentando-se com pródromo febril e sintomas semelhantes aos de um resfriado comum, podendo rapidamente evoluir para edema pulmonar, insuficiência respiratória aguda e choque. A hemoconcentração e a plaquetopenia são comuns da síndrome pulmonar e cardiovascular por hantavírus, e o quadro radiológico típico é de um infiltrado intersticial bilateral difuso, que progride rapidamente para consolidações alveolares, paralelamente à piora do quadro clínico. A mortalidade inicial era em torno de 75% e declinou para aproximadamente 35%, nos últimos anos. Os pacientes que sobrevivem geralmente recuperam-se completamente, cerca de uma semana após o estabelecimento do quadro respiratório. O agente causal, não reconhecido até há pouco, foi identificado como um hantavírus, cujo reservatório natural são animais roedores da família Muridae, subfamília Sigmodontinae. O tratamento específico antiviral ainda não é bem estabelecido, estando em estudo a eficácia de ribavirina. Cuidados de terapia intensiva como ventilação mecânica e monitoramento hemodinâmico invasivo são necessários nas formas mais graves da doença. Essas medidas, se instituídas precocemente, podem melhorar o prognóstico e a sobrevida dos pacientes com síndrome pulmonar e cardiovascular por hantavírus.Hantavirus pulmonary and cardiovascular syndrome is a recently identified and often fatal disease, which presents as acute respiratory distress syndrome (ARDS. Since the first outbreak, in Nov/Dec 1993, in Juquitiba, Brazil, 226 cases have been registered by

  9. Pathogenesis and host response in Syrian hamsters following intranasal infection with Andes virus.

    Directory of Open Access Journals (Sweden)

    David Safronetz

    2011-12-01

    Full Text Available Hantavirus pulmonary syndrome (HPS, also referred to as hantavirus cardiopulmonary syndrome (HCPS, is a rare but frequently fatal disease caused by New World hantaviruses. In humans HPS is associated with severe pulmonary edema and cardiogenic shock; however, the pathogenesis of this disease remains unclear largely due to a lack of suitable animal models for the study of disease progression. In this study we monitored clinical, virological, pathophysiological parameters and host immunological responses to decipher pathological factors and events in the lethal Syrian hamster model of HPS following intranasal inoculation of Andes virus. Transcriptional profiling of the host gene responses demonstrated a suppression of innate immune responses in most organs analyzed during the early stage of infection, except for in the lung which had low level activation of several pro-inflammatory genes. During this phase Andes virus established a systemic infection in hamsters, with viral antigen readily detectable in the endothelium of the majority of tissues analyzed by 7-8 days post-inoculation. Despite wide-spread infection, histological analysis confirmed pathological abnormalities were almost exclusively found in the lungs. Immediately preceding clinical signs of disease, intense activation of pro-inflammatory and Th1/Th2 responses were observed in the lungs as well as the heart, but not in peripheral organs, suggesting that localized immune-modulations by infection is paramount to pathogenesis. Throughout the course of infection a strong suppression of regulatory T-cell responses was noted and is hypothesized to be the basis of the aberrant immune activations. The unique and comprehensive monitoring of host immune responses to hantavirus infection increases our understanding of the immuno-pathogenesis of HPS and will facilitate the development of treatment strategies targeting deleterious host immunological responses.

  10. Cult sites in northern Sweden

    Directory of Open Access Journals (Sweden)

    Stefan Brink

    1990-01-01

    Full Text Available The pagan cult in northern Sweden, i.e, Norrland, has for some decades been a neglected chapter in our history, a situation which unfortunately applies to Sweden as a whole, at least where onomastics are concerned. The aim is thus to deliver an overview of the evidence that we have of pre-Christian religious activities in these northern parts — in this aspect, onomastic material is nearly almost all we have got — and some general remarks about the conversion to the new Christian religion. The area of investigation is what in the (Swedish medieval period was known as Norrland. In other words, the part of Sweden considered here is modern Central Norrland. With our state of knowledge of today it is not so easy to pick out the place-names that have denoted some kind of pagan cult activity. The place-name material can be divided into: 1. Theoforic place-names 2. place-names denoting the site of a pagan cult, which do not however contain theoforic elements 3. place-names with a possible pagan cultic element.

  11. Energy Foresight - Sweden in Europe

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-07-01

    The IVA-project 'Energy Foresight - Sweden in Europe' deals with possibilities and problems associated with our energy future. We take it for granted that various forms of energy will always be available for a multitude of purposes and at acceptable prices. Sweden also places high demands on health and environmental protection issues when it comes to the production of power and heat. During the last few years the climate issue has been highlighted, which in turn will change the conditions for the use of alternative sources of energy. Carbon dioxide is the most important of the greenhouse gases, and it is closely associated with the burning of coal, oil, and natural gas. These fossil fuels play dominant roles in the world 's energy supply. Far-reaching measures to decrease carbon dioxide emissions will thus greatly affect the ways in which we use fossil fuels and non-carbon dioxide generating sources of energy. We have chosen a global starting point for our energy study. From there we will zoom in on the energy systems of Europe and Sweden. The climate issue demands global approach. Deregulation of electricity and gas markets, and the development of integrated European systems related to these energy sources, requires an international perspective on he Swedish energy system. Our project differs from earlier governmental energy studies in the sense that we are not trying to present the most likely, nor the most desirable energy future. Instead we have opted to draw up some illustrations of Sweden's future energy system, with Europe as a backdrop. The climate issue differentiates the scenarios. Our time perspective is 20 years, with glimpses 50 years ahead. On the 18th of February 2003, the Steering Group of Energy Foresight - Sweden in Europe, presented it's final report. The bulk of the work has been done in four panels. Their reflections and conclusions are presented in separate panel reports. The 12 factual reports present different

  12. Energy Foresight - Sweden in Europe

    International Nuclear Information System (INIS)

    2003-01-01

    The IVA-project 'Energy Foresight - Sweden in Europe' deals with possibilities and problems associated with our energy future. We take it for granted that various forms of energy will always be available for a multitude of purposes and at acceptable prices. Sweden also places high demands on health and environmental protection issues when it comes to the production of power and heat. During the last few years the climate issue has been highlighted, which in turn will change the conditions for the use of alternative sources of energy. Carbon dioxide is the most important of the greenhouse gases, and it is closely associated with the burning of coal, oil, and natural gas. These fossil fuels play dominant roles in the world 's energy supply. Far-reaching measures to decrease carbon dioxide emissions will thus greatly affect the ways in which we use fossil fuels and non-carbon dioxide generating sources of energy. We have chosen a global starting point for our energy study. From there we will zoom in on the energy systems of Europe and Sweden. The climate issue demands global approach. Deregulation of electricity and gas markets, and the development of integrated European systems related to these energy sources, requires an international perspective on he Swedish energy system. Our project differs from earlier governmental energy studies in the sense that we are not trying to present the most likely, nor the most desirable energy future. Instead we have opted to draw up some illustrations of Sweden's future energy system, with Europe as a backdrop. The climate issue differentiates the scenarios. Our time perspective is 20 years, with glimpses 50 years ahead. On the 18th of February 2003, the Steering Group of Energy Foresight - Sweden in Europe, presented it's final report. The bulk of the work has been done in four panels. Their reflections and conclusions are presented in separate panel reports. The 12 factual reports present different sources of energy, how hey are

  13. Phylogenetic analysis of Puumala virus strains from Central Europe highlights the need for a full-genome perspective on hantavirus evolution.

    Science.gov (United States)

    Szabó, Róbert; Radosa, Lukáš; Ličková, Martina; Sláviková, Monika; Heroldová, Marta; Stanko, Michal; Pejčoch, Milan; Osterberg, Anja; Laenen, Lies; Schex, Susanne; Ulrich, Rainer G; Essbauer, Sandra; Maes, Piet; Klempa, Boris

    2017-12-01

    Puumala virus (PUUV), carried by bank voles (Myodes glareolus), is the medically most important hantavirus in Central and Western Europe. In this study, a total of 523 bank voles (408 from Germany, 72 from Slovakia, and 43 from Czech Republic) collected between the years 2007-2012 were analyzed for the presence of hantavirus RNA. Partial PUUV genome segment sequences were obtained from 51 voles. Phylogenetic analyses of all three genome segments showed that the newfound strains cluster with other Central and Western European PUUV strains. The new sequences from Šumava (Bohemian Forest), Czech Republic, are most closely related to the strains from the neighboring Bavarian Forest, a known hantavirus disease outbreak region. Interestingly, the Slovak strains clustered with the sequences from Bohemian and Bavarian Forests only in the M but not S segment analyses. This well-supported topological incongruence suggests a segment reassortment event or, as we analyzed only partial sequences, homologous recombination. Our data highlight the necessity of sequencing all three hantavirus genome segments and of a broader bank vole screening not only in recognized endemic foci but also in regions with no reported human hantavirus disease cases.

  14. The history of tuberculosis management in Sweden.

    Science.gov (United States)

    Wallstedt, Helen; Maeurer, Markus

    2015-03-01

    We review the history of TB in Sweden beginning in 1800, when 25% of mortality in Sweden was associated with TB. The Royal Family was involved in establishing dedicated sanatoria in Sweden to offer better diagnostics and clinical care. TB has declined in Sweden steadily, with some recent increases due to local spread of TB and challenging international and national socio-economical structures. Improved research and clinical knowledge is needed to diagnose and manage drug-susceptible as well as drug-resistant TB. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  15. The History of Tuberculosis Management in Sweden

    Directory of Open Access Journals (Sweden)

    Helen Wallstedt

    2015-03-01

    Full Text Available We review the history of TB in Sweden beginning in 1800, when 25% of mortality in Sweden was associated with TB. The Royal Family was involved in establishing dedicated sanatoria in Sweden to offer better diagnostics and clinical care. TB has declined in Sweden steadily, with some recent increases due to local spread of TB and challenging international and national socio-economical structures. Improved research and clinical knowledge is needed to diagnose and manage drug-susceptible as well as drug-resistant TB.

  16. Cadmium in Sweden - environmental risks

    Energy Technology Data Exchange (ETDEWEB)

    Parkman, H; Iverfeldt, Aa [Swedish Environmental Research Inst. (Sweden); Borg, H; Lithner, G [Stockholm Univ. (Sweden). Inst. for Applied Environmental Research

    1998-03-01

    This report aims at assessing possible effects of cadmium in the Swedish environment. Swedish soils and soft freshwater systems are, due to a generally poor buffering capacity, severely affected by acidification. In addition, the low salinity in the Baltic Sea imply a naturally poor organism structure, with some important organisms living close to their limit of physiological tolerance. Cadmium in soils is mobilized at low pH, and the availability and toxicity of cadmium in marine systems are enhanced at low salinity. The Swedish environment is therefore extra vulnerable to cadmium pollution. The average concentrations of cadmium in the forest mor layers, agricultural soils, and fresh-waters in Sweden are enhanced compared to `back-ground concentrations`, with a general increasing trend from the north to the south-west, indicating strong impact of atmospheric deposition of cadmium originating from the central parts of Europe. In Swedish sea water, total cadmium concentrations, and the fraction of bio-available `free` cadmium, generally increases with decreasing salinity. Decreased emissions of cadmium to the environment have led to decreasing atmospheric deposition during the last decade. The net accumulation of cadmium in the forest mor layer has stopped, and even started to decrease. In northern Sweden, this is due to the decreased deposition, but in southern Sweden the main reason is increased leakage of cadmium from the topsoil as a consequence of acidification. As a result, cadmium in the Swedish environments is undergoing an extended redistribution between different soil compartments, and from the soils to the aquatic systems. 90 refs, 23 figs, 2 tabs. With 3 page summary in Swedish

  17. Aespoe hard rock laboratory Sweden

    International Nuclear Information System (INIS)

    1992-01-01

    The aim of the new Aespoe hard rock laboratory is to demonstrate state of the art of technology and evaluation methods before the start of actual construction work on the planned deep repository for spent nuclear fuel. The nine country OECD/NEA project in the Stripa mine in Sweden has been an excellent example of high quality international research co-operation. In Sweden the new Aespoe hard rock laboratory will gradually take over and finalize this work. SKB very much appreciates the continued international participation in Aespoe which is of great value for the quality efficiency, and confidence in this kind of work. We have invited a number of leading experts to this first international seminar to summarize the current state of a number of key questions. The contributions show the great progress that has taken place during the years. The results show that there is a solid scientific basis for using this knowledge on site specific preparation and work on actual repositories. (au)

  18. Hantavirus Gc induces long-term immune protection via LAMP-targeting DNA vaccine strategy.

    Science.gov (United States)

    Jiang, Dong-Bo; Zhang, Jin-Peng; Cheng, Lin-Feng; Zhang, Guan-Wen; Li, Yun; Li, Zi-Chao; Lu, Zhen-Hua; Zhang, Zi-Xin; Lu, Yu-Chen; Zheng, Lian-He; Zhang, Fang-Lin; Yang, Kun

    2018-02-01

    Hemorrhagic fever with renal syndrome (HFRS) occurs widely throughout Eurasia. Unfortunately, there is no effective treatment, and prophylaxis remains the best option against the major pathogenic agent, hantaan virus (HTNV), which is an Old World hantavirus. However, the absence of cellular immune responses and immunological memory hampers acceptance of the current inactivated HFRS vaccine. Previous studies revealed that a lysosome-associated membrane protein 1 (LAMP1)-targeting strategy involving a DNA vaccine based on the HTNV glycoprotein Gn successfully conferred long-term immunity, and indicated that further research on Gc, another HTNV antigen, was warranted. Plasmids encoding Gc and lysosome-targeted Gc, designated pVAX-Gc and pVAX-LAMP/Gc, respectively, were constructed. Proteins of interest were identified by fluorescence microscopy following cell line transfection. Five groups of 20 female BALB/c mice were subjected to the following inoculations: inactivated HTNV vaccine, pVAX-LAMP/Gc, pVAX-Gc, and, as the negative controls, pVAX-LAMP or the blank vector pVAX1. Humoral and cellular immunity were assessed by enzyme-linked immunosorbent assays (ELISAs) and 15-mer peptide enzyme-linked immunospot (ELISpot) epitope mapping assays. Repeated immunization with pVAX-LAMP/Gc enhanced adaptive immune responses, as demonstrated by the specific and neutralizing antibody titers and increased IFN-γ production. The inactivated vaccine induced a comparable humoral reaction, but the negative controls only elicited insignificant responses. Using a mouse model of HTNV challenge, the in vivo protection conferred by the inactivated vaccine and Gc-based constructs (with/without LAMP recombination) was confirmed. Evidence of pan-epitope reactions highlighted the long-term cellular response to the LAMP-targeting strategy, and histological observations indicated the safety of the LAMP-targeting vaccines. The long-term protective immune responses induced by pVAX-LAMP/Gc may be

  19. A central spent fuel storage in Sweden

    International Nuclear Information System (INIS)

    Gustafsson, B.; Hagberth, R.

    1978-01-01

    A planned central spent fuel storage facility in Sweden is described. The nuclear power program and quantities of spent fuel generated in Sweden is discussed. A general description of the facility is given with emphasis on the lay-out of the buildings, transport casks and fuel handling. Finally a possible design of a Swedish transportation system is discussed. (author)

  20. ASEA reduces nuclear waste in Sweden

    International Nuclear Information System (INIS)

    Anon.

    1977-01-01

    ASEA, the worldwide manufacturer of electrical and mechanical equipment with headquarters in Vasteras, Sweden, is working on the development of a method using hot isostatic pressing for the safe containment and storage of nuclear waste. This development work is being carried out at the company's High-Pressure Laboratory at Robertsfors, in the north of Sweden

  1. Public Procurement of Innovation in Sweden

    DEFF Research Database (Denmark)

    Rolfstam, Max; Ågren, Robert

    2014-01-01

    Sweden is often thought of as a country with a strong tradition for using public procurement as a means to stimulate innovation. Early on, Sweden recognized and developed procedures for using public procurement as a technologydevelopment tool. After a period where emphasis was put on this aspect ...... government authorities to engage in public procurement for innovation, and by issuing guidance on the topic.......Sweden is often thought of as a country with a strong tradition for using public procurement as a means to stimulate innovation. Early on, Sweden recognized and developed procedures for using public procurement as a technologydevelopment tool. After a period where emphasis was put on this aspect...... of public procurement Sweden dropped many policy initiatives within this field. This was in part due to neo-liberal movements during the 1980s which in interaction with a distributed institutional setup led to the removal of incentives for a procuring authority to engage in public procurement of innovation...

  2. Research on Pentecostalism in Sweden

    Directory of Open Access Journals (Sweden)

    Jan-Åke Alvarsson

    2015-05-01

    Full Text Available This article aims to orientate and introduce potential researchers into Swedish Pentecostal movements, or those who wish to provide an overview of Scandinavian Christianity, by giving a brief summary of the history of Pentecostalism in Sweden and an overview of the main academic monographs that have been produced on this particular branch of Christianity. The idea is to highlight areas where we find relevant research and to point to areas into which there has been little or no investigation. Following, by way of introduction, a brief historical sketch, there is a note on spirituality before we are given a review of some thirty major academic works on the subject that a potential researcher would need to take into consideration.

  3. Chernobyl - its impact on Sweden

    International Nuclear Information System (INIS)

    1986-08-01

    In case of radiological emergency in Sweden, the Swedish National Institute of Radiation Protection (SSI) has the responsability of organizing a special task force with experts both from SSI and from other authorities. Reports of increased radiation levels reached SSI around 10 am on April 28, 1986, and the task force convened at 1030 am. A large number of measurements were made all over the country, and temporary grazing restrictions were imposed so as to aviod excessive doses from the food chain grass-cow-milk. Attention is now concentrated on regions with high cesium activity and on foodstuffs in general. A very tentative estimate of the collective dose commiment is 10 000 man.Sv. It turned out that the general public was not always satisfied with the information provided by the authorities, in spite of complete openness (Author)

  4. Radioactive wast management in Sweden

    International Nuclear Information System (INIS)

    Sivintsev, Yu.V.

    1985-01-01

    A system under development and partially realized of NPP radioactive waste management in Sweden up to spent-fuel disposal in underground storage is described. The system implies that the spent fuel after unloading from a reactor is stored at the NPP in water shielded tanks. Then fuel assemblies (FA) are transforted by a special ship, being operated since 1982, to the CLAB central storage. In CLAB water pools lacated in underground granite openings fuel assemblies will be stored for 40 years. CLAB is suggested to be put in operation in 1985. At the next stage FA are transported from CLAB to the canning set-up (located on the ground above the under ground disposal). Hot isostatic pressing is used for hermetization as a method allowing to make monolithic copper containers with a storage time of about 1 mln years. Sealed copper containers will be put into a burial ground sited in crystal rocks

  5. Radon in dwellings in Sweden

    International Nuclear Information System (INIS)

    Swedjemark, G.A.

    1980-01-01

    Studies on specific activities in building materials, gamma-radiation levels in dwellings, the concentrations of radon and daughters in the air indoors and the concentration of radon in tap water are in progress in Sweden. On the basis of these investigations and of the investigation of Hultqvist from the beginning of the 1950's, an attempt has been made to show how the radiation doses in dwellings have changed or may be changed by human activities and what these changes imply in terms of collective dose. The annual collective absorbed dose in the basal cells of the critical bronchial region have increased from 11 x 10 3 man-Gy for the occupants of dwellings existing in 1950 to 25 x 10 3 man-Gy for dwellings existing in 1975

  6. Incidence of hyperthyroidism in Sweden.

    Science.gov (United States)

    Abraham-Nordling, Mirna; Byström, Kristina; Törring, Ove; Lantz, Mikael; Berg, Gertrud; Calissendorff, Jan; Nyström, Helena Filipsson; Jansson, Svante; Jörneskog, Gun; Karlsson, F Anders; Nyström, Ernst; Ohrling, Hans; Orn, Thomas; Hallengren, Bengt; Wallin, Göran

    2011-12-01

    The incidence of hyperthyroidism has been reported in various countries to be 23-93/100,000 inhabitants per year. This extended study has evaluated the incidence for ~40% of the Swedish population of 9 million inhabitants. Sweden is considered to be iodine sufficient country. All patients including children, who were newly diagnosed with overt hyperthyroidism in the years 2003-2005, were prospectively registered in a multicenter study. The inclusion criteria are as follows: clinical symptoms and/or signs of hyperthyroidism with plasma TSH concentration below 0.2 mIE/l and increased plasma levels of free/total triiodothyronine and/or free/total thyroxine. Patients with relapse of hyperthyroidism or thyroiditis were not included. The diagnosis of Graves' disease (GD), toxic multinodular goiter (TMNG) and solitary toxic adenoma (STA), smoking, initial treatment, occurrence of thyroid-associated eye symptoms/signs, and demographic data were registered. A total of 2916 patients were diagnosed with de novo hyperthyroidism showing the total incidence of 27.6/100,000 inhabitants per year. The incidence of GD was 21.0/100,000 and toxic nodular goiter (TNG=STA+TMNG) occurred in 692 patients, corresponding to an annual incidence of 6.5/100,000. The incidence was higher in women compared with men (4.2:1). Seventy-five percent of the patients were diagnosed with GD, in whom thyroid-associated eye symptoms/signs occurred during diagnosis in every fifth patient. Geographical differences were observed. The incidence of hyperthyroidism in Sweden is in a lower range compared with international reports. Seventy-five percent of patients with hyperthyroidism had GD and 20% of them had thyroid-associated eye symptoms/signs during diagnosis. The observed geographical differences require further studies.

  7. Síndrome pulmonar por hantavirus en población infantil. Chile: Regiones IX y X. 1998-2000

    OpenAIRE

    SOZA C., GUILLERMO; LORCA O., PEDRO; PUEBLA M., SERGIO; WENZEL M., MARISOL; NAVARRETE C., MARITZA; VILLAGRA C., ELIECER; MORA R., JUDITH; LEVIS C., SILVANA; AVILES A., GABRIELA

    2000-01-01

    El síndrome pulmonar por hantavirus (SPH) ha estado presente en Chile desde 1993 y ha sido detectado desde 1997 en la IX Región. Es una grave zoonosis con alta mortalidad, que afecta a gente joven incluyendo niños. Se ha estimado oportuno dar a conocer nuestra experiencia en la atención de 6 pacientes pediátricos, atendidos en las unidades de Cuidados Intensivos y Aislamiento en el Hospital Regional de Temuco, entre enero de 1998 y enero de 2000 mediante un estudio descriptivo de la experienc...

  8. Energy in Sweden. Facts and figures 2005

    International Nuclear Information System (INIS)

    2005-12-01

    Energy in Sweden. Facts and Figures 2005 contains the tabular data for most of the diagrams in the main publication. These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. Facts and Figures is available at www.stem.se in pdf- and excel file formats. With effect from the 2001 edition, statistics are of preliminary character for the two preceding years (2003 and 2004). Breakdowns into certain types of fuels vary somewhat depending on whether preliminary or final data has been used. Further information about the statistics can be found in Energy in Sweden, chapter 8 Energy Facts

  9. Occupational Gender Composition and Wages in Sweden

    OpenAIRE

    Hansen, Jörgen; Wahlberg, Roger

    2000-01-01

    We estimate the relationship between wages and occupational gender segregation in Sweden. Because of high wage equality in Sweden compared to the U.S., we expect a lower wage penalty of job femaleness in Sweden than in the U.S. Our results supports this hypothesis. We also investigate how the unexplained gender wage gap vary across occupations and find that this gap is smallest in male dominated jobs and largest in female dominated jobs. Finally, we investigate whether the female wage-experie...

  10. Renewable Energy Policy Fact sheet - Sweden

    International Nuclear Information System (INIS)

    2017-09-01

    The EurObserv'ER policy profiles give a snapshot of the renewable energy policy in the EU Member States. Sweden surpassed its 2020 nationally binding renewable energy in 2013. Main support measures to promote renewable energy in Sweden consists of a quota system, various tax regulation mechanisms and subsidy schemes. Sweden has a joint support scheme with Norway, thus being the first EU Member State to implement a cooperation mechanism, as defined under the 2009 EU Renewable Energy Directive. The Swedish coalition government has agreed on a target of 100% renewable electricity production by 2040

  11. Dynamics of Puumala virus infection in bank voles in Ardennes department (France).

    Science.gov (United States)

    Augot, D; Muller, D; Demerson, J M; Boué, F; Caillot, C; Cliquet, F

    2006-12-01

    The hantaviruses (genus Hantavirus, family Bunyaviridae) include human pathogens and occur worldwide. In Western and Central Europe, the predominant serotype is Puumala (PUU) virus, which causes epidemic nephropathy. Voles are considered to be the main reservoir and the vector of PUU virus. A total of 719 rodents (mainly Clethrionomys glareolus, Apodemus sp.) trapped by capture-mark-recapture (CMR) in four sites in Ardennes department (France) between April 2004 and October 2005 were tested for the presence of PUU virus antibodies by enzyme-linked immunosorbent assay (ELISA). The predominant species, C. glareolus (86.5% [622 of 719]), also had the highest antibody prevalence (37.6% [291 of 773]). In C. glareolus, the antibody prevalence rate increased with age (weight) in site A, B and D, reaching more than 50% in the heaviest weight, and suggesting that horizontal infection may be important.

  12. Development of nuclear power in Sweden

    International Nuclear Information System (INIS)

    Sokolowski, E.

    1994-01-01

    The history and development of nuclear energetics in Sweden has been described. Up to now 12 units (9 BWR and 3 PWR nuclear reactors) with total 70 TWh electric power is being working in Sweden. If the same power will be installed as a coal-fired units the emissions of 65 million tons of CO 2 , 240,000 tons of SO 2 and 140 tons of NO x would be expected. 1 tab

  13. Radon in dwellings in Sweden

    International Nuclear Information System (INIS)

    Swedjemark, G.A.

    1978-04-01

    Studies on the specific activities in building materials, the γ-radiation levels in dwellings, the concentrations of radon and daughters in the air indoors and the concentration of radon in tap water are in progress in Sweden. On basis of these investigations and of the investigation of Hultqvist from the beginning of the 1950s, an attempt has been made to show how the radiation doses in dwellings have changed or may be changed by human activities and what these changes imply in terms of collective dose. The annual collective absorbed dose in the basal cells of the critical bronchial region have increased from 11 . 10 3 manGy for the occupants of dwellings existing in 1950 to 25 . 10 3 manGy for dwellings existing in 1975. If the building of houses continues as at present it can be estimated that the annual collective dose will be between 25 and 31 . 10 3 manGy for the dwellings of 1985. (author)

  14. Ageing management requirements in Sweden

    International Nuclear Information System (INIS)

    Gott, K.

    2007-01-01

    Since the adoption of the 1997 act of parliament concerning the abolishment of nuclear power in Sweden plant lives are no longer limited until 2010 as they were following the referendum in 1980. The Swedish Nuclear Power Inspectorate (SKI) has therefore in its most recent general regulations from 2004 introduced requirements for plants to develop ageing management programmes which should have been in place by the end of 2005. An ageing management programme for a nuclear power plant can be viewed as a high level coordinated programme consisting of several other programmes including maintenance and inspection programmes, and as such it should be an integrated part of the quality assurance system of the plant. The goals of the programme are to ensure that there is long term management of ageing and avoidance of the unexpected. For the Swedish regulator the safety aspects and not the economic aspects of ageing management are of primary importance. But there are clear advantages to utilities if large surprises which result in unplanned outages can be avoided. (author)

  15. Relating increasing hantavirus incidences to the changing climate: the mast connection

    Directory of Open Access Journals (Sweden)

    Maes Piet

    2009-01-01

    Full Text Available Abstract Background Nephropathia epidemica (NE, an emerging rodent-borne viral disease, has become the most important cause of infectious acute renal failure in Belgium, with sharp increases in incidence occurring for more than a decade. Bank voles are the rodent reservoir of the responsible hantavirus and are known to display cyclic population peaks. We tried to relate these peaks to the cyclic NE outbreaks observed since 1993. Our hypothesis was that the ecological causal connection was the staple food source for voles, being seeds of deciduous broad-leaf trees, commonly called "mast". We also examined whether past temperature and precipitation preceding "mast years" were statistically linked to these NE outbreaks. Results Since 1993, each NE peak is immediately preceded by a mast year, resulting in significantly higher NE case numbers during these peaks (Spearman R = -0.82; P = 0.034. NE peaks are significantly related to warmer autumns the year before (R = 0.51; P Conclusion NE peaks in year 0 are induced by abundant mast formation in year-1, facilitating bank vole survival during winter, thus putting the local human population at risk from the spring onwards of year 0. This bank vole survival is further promoted by higher autumn temperatures in year-1, whereas mast formation itself is primed by higher summer temperatures in year-2. Both summer and autumn temperatures have been rising to significantly higher levels during recent years, explaining the virtually continuous epidemic state since 2005 of a zoonosis, considered rare until recently. Moreover, in 2007 a NE peak and an abundant mast formation occurred for the first time within the same year, thus forecasting yet another record NE incidence for 2008. We therefore predict that with the anticipated climate changes due to global warming, NE might become a highly endemic disease in Belgium and surrounding countries.

  16. Electricity supply in Sweden 1983

    International Nuclear Information System (INIS)

    1984-01-01

    The year 1983 was characterized by a continued decrease in oil consumption and an increase in electricity consumption. Totally the supply of fuels decreased from 278TWh to 264 TWh in 1983. The electricity supply increased from 99.9 TWh in 1982 to 110.8 TWh in 1983. The consumers total energy use decreased from 358 TWh in 1982 to 355 TWh in 1983. Electricity consumption excluding transmission losses increased from 91,4 TWh in 1982 to 101.1TWh in 1983. The increase was due to electric space heating disconnectable electric boilers and to industry. At the end of 1983 the electric heating subscriptions are estimated to corresponds to 45 percent of all one-family houses. Hydropower accounted for 54 percent and nucler power accounted for 34 percent of the total supply of electricity in 1983. The highest hourly load during 1983 amounted to 20862 MW. The lowest load during 1983 amounted to 5185 MW. Ten nuclear power units were in commercial operation during the year. The energy availability figures were as follows: Barsebaeck 1 85 percent, Barsebaeck 2 82 percent, Forsmark 1 84 percent, Forsmark 2 88 percent, Oskarshamn 1 87 percent, Oskarshamn 2 83 percent, Ringhals 1 59 percent and Ringhals 2 68 percent. The production of electricity from conventional thermal power stations was only 4.0 TWh. Back pressure power in industry contributed 2.5 TWh of this figure and combined power and district heating stations 1.3 TWh. Two coal fired combined power and district heating plants were added and sevearl combined power and district heating plants have been rebuilt to be coal fired. The high voltage power grid system permits joint operation by all the power companies in the country, and the major power companies utilize the network for exchanging surplus power with other power companies. An account of the public debate on energy in Sweden during 1983 is also given.(L.E.)

  17. CO2 storage in Sweden

    International Nuclear Information System (INIS)

    Ekstroem, Clas; Andersson, Annika; Kling, Aasa; Bernstone, Christian; Carlsson, Anders; Liljemark, Stefan; Wall, Caroline; Erstedt, Thomas; Lindroth, Maria; Tengborg, Per; Edstroem, Mikael

    2004-07-01

    This study considers options, that could be feasible for Sweden, to transport and geologically store CO 2 , providing that technology for electricity production with CO 2 capture will be available in the future and also acceptable from cost- and reliability point of view. As a starting point, it is assumed that a new 600-1000 MW power plant, fired with coal or natural gas, will be constructed with CO 2 capture and localised to the Stockholm, Malmoe or Goeteborg areas. Of vital importance for storage of carbon dioxide in a reservoir is the possibility to monitor its distribution, i.e. its migration within the reservoir. It has been shown in the SACS-project that the distribution of carbon dioxide within the reservoir can be monitored successfully, mainly by seismic methods. Suitable geologic conditions and a large storage potential seems to exist mainly in South West Scania, where additional knowledge on geology/hydrogeology has been obtained since the year 2000 in connection to geothermal energy projects, and in the Eastern part of Denmark, bordering on South West Scania. Storage of carbon dioxide from the Stockholm area should not be excluded, but more studies are needed to clarify the storage options within this area. The possibilities to use CO 2 for enhanced oil recovery, EOR, in i.a. the North Sea should be investigated, in order to receive incomes from the CO 2 and shared costs for infrastructure, and by this also make the CO 2 regarded as a trading commodity, and thereby achieving a more favourable position concerning acceptance, legal issues and regulations. The dimensions of CO 2 -pipelines should be similar to those for natural natural gas, although regarding some aspects they have different design and construction prerequisites. To obtain cost efficiency, the transport distances should be kept short, and possibilities for co-ordinated networks with short distribution pipelines connected to common main pipelines, should be searched for. Also, synergies

  18. First identification of Echinococcus multilocularis in rodent intermediate hosts in Sweden

    Directory of Open Access Journals (Sweden)

    Andrea L. Miller

    2016-04-01

    Full Text Available Echinococcus multilocularis is a zoonotic tapeworm with a sylvatic lifecycle and an expanding range in Europe. Monitoring efforts following its first identification in 2011 in Sweden have focused on the parasite's definitive host, the red fox (Vulpes vulpes. However, identifying rodent intermediate hosts is important to recognize opportunities for parasite transmission. During 2013–2015, livers from a total of 1566 rodents from four regions in Sweden were examined for E. multilocularis metacestode lesions. Species identity of suspect parasite lesions was confirmed by PCR and sequencing. E. multilocularis positive lesions >6 mm in diameter were also examined histologically. One Microtus agrestis out of 187 (0.5%, 95%CI: 0–2.9%, 8/439 (1.8%, 95%CI: 0.8–3.6% Arvicola amphibius, 0/655 (0%, 95%CI: 0–0.6% Myodes glareolus, and 0/285 (0%, 95%CI: 0–1.3% Apodemus spp. contained E. multilocularis metacestode lesions. Presence of protoscoleces was confirmed in the infected M. agrestis and in three of eight infected A. amphibius. Six of the nine positive rodents were captured from the same field. This is the first report of E. multilocularis in intermediate hosts in Sweden. The cluster of positive rodents in one field shows that local parasite prevalence can be high in Sweden despite overall low national prevalence in foxes (<0.1%. The presence of protoscoleces in infected M. agrestis and A. amphibius indicate these species can serve as competent intermediate hosts in Sweden. However, their relative importance for E. multilocularis transmission in the Swedish environment is not yet possible to assess. In contrast, the negative findings in all M. glareolus and Apodemus spp. suggest that these species are of no importance.

  19. Síndrome pulmonar por hantavírus com disfunção de múltiplos órgãos: relato de caso Hantavirus pulmonary syndrome with multiple organ dysfunctions: case report

    Directory of Open Access Journals (Sweden)

    Marcelo Spegiorin Moreno

    2007-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A hantavirose é uma zoonose que apresenta distribuição mundial e sua transmissão está relacionada com o íntimo contato com roedores. Causa dois tipos de doença: a febre hemorrágica com síndrome renal (FHSR, endêmica na Ásia e Europa e a síndrome pulmonar por hantavírus (SPH, encontrada no continente americano, inclusive no Brasil, com elevadas taxas de mortalidade. O objetivo deste estudo foi relatar um caso de SPH com disfunção de múltiplos órgãos, que recebeu tratamento intensivo precoce e reanimação guiada por parâmetros de fluxo e de perfusão tecidual. RELATO DO CASO: Paciente do sexo masculino, 36 anos, iniciou quadro febril inespecífico, dispnéia progressiva, hipóxia grave e insuficiência respiratória aguda. Apresentava infiltrado interstício-alveolar difuso na radiografia de tórax. Evoluiu com disfunção de múltiplos órgãos (pulmonar, renal, hematológica, cardiovascular e metabólica. Recebeu tratamento e monitorização hemodinâmica invasiva precoces. As alterações laboratoriais mais importantes foram plaquetopenia, elevação dos níveis de hematócrito e hemoglobina, leucocitose, elevação de transaminases, de lactado desidrogenase e sorologia positiva para hantavírus (ELISA IgM positivo. O paciente apresentou reversão das disfunções orgânicas, recebendo alta hospitalar após 21 dias de hospitalização. CONCLUSÕES: A reanimação precoce e agressiva dirigida por metas levou à reversão da síndrome de falência de múltiplos órgãos e a um desfecho clínico favorável, apesar da gravidade da doença.BACKGROUND AND OBJECTIVES: Hantavirus infection is a zoonose with worldwide distribution. The transmission is related to the intimal contact with rodents. It causes two syndromes: hemorrhagic fever with renal syndrome (HFRS, endemic in Asia and Europe and the Hantavirus pulmonary syndrome (HPS, found in the American continent, including Brazil, with high mortality

  20. Andes virus infections in the rodent reservoir and in humans vary across contrasting landscapes in Chile

    Science.gov (United States)

    Torres-Pérez, Fernando; Palma, R. Eduardo; Hjelle, Brian; Ferres, Marcela; Cook, Joseph A.

    2009-01-01

    Hantavirus cardiopulmonary syndrome (HCPS) is an emerging infectious disease first reported in Chile in 1995. Andes hantavirus (ANDV) is responsible for the more than 500 cases of HCPS reported in Chile. Previous work showed that ANDV is genetically differentiated in Chile across contrasting landscapes. To determine whether the reservoir rodent (Oligoryzomys longicaudatus) populations are also geographically segregated, we conducted range-wide spatial genetic analyses of O. longicaudatus in Chile using the mitochondrial DNA cytochrome b gene. Given that landscape structure influences the incidence of hantavirus infections, we also tested 772 O. longicaudatus specimens for antibodies to ANDV captured during the period 2000 − 2006. Population genetic analyses of O. longicaudatus are largely congruent with those reported for ANDV, with the host primarily differentiated according to three defined ecoregions, Mediterranean, Valdivian rain forest and North Patagonian rain forest. Significant differences in the relative prevalence of anti-ANDV antibodies in rodent samples also were found across the three ecoregions. We relate these results to the number of reported human HCPS cases in Chile, and discuss the importance of landscape differences in light of ANDV transmission to humans and among rodent populations. PMID:19632357

  1. Condiciones para la transmision del hantavirus en zona andina de Río negro, Argentina

    Directory of Open Access Journals (Sweden)

    Gabriel Talmon

    2014-10-01

    Full Text Available El Síndrome Pulmonar por Hantavirus (SPH es una enfermedad de etiología viral que causa en el hombre un cuadro respiratorio grave. En Patagonia, la enfermedad es causada por el virus Andes Sur (AND, transmitido por el roedor Oligoryzomys longicaudatus. El objetivo del presente trabajo fue identificar las actividades del hombre que favorecen su exposición a roedores, denominados escenarios de contagio. Se realizó un estudio retrospectivo a partir de información recolectada en investigaciones de casos ocurridos en Río Negro, mediante Fichas Clínico-Epidemiológicas e informes de evaluación ecológico/ambiental. Se definieron como variables a ser consideradas: edad, sexo, época del año, grado de urbanización, localización geográfica, integración del hombre al hábitat de roedores, fuente probable de exposición, actividad humana y nivel de saneamiento. Se estudiaron 32 casos. La exposición rural se verificó en 18 (56.2% de los casos y 10 (31.3% en paraje rural (grupo de viviendas en zona rural. En relación al ambiente antropogénico 24 (75% resultaron en ambientes modificados por el hombre y 8 (25% en áreas poco modificadas. El sitio de exposición de mayor importancia en El Bolsón fue el interior de edificaciones en 8 de los 18 casos allí registrados (44.5%, mientras que en Bariloche fueron ambientes de exterior con 8/14 (57.1% casos. La actividad de riesgo fue laboral en 23 (71.9% de los casos y recreacional en 7 (28.1%. Determinar los escenarios de contagio a nivel local ha aportado información para aplicar todos los recursos disponibles en materia de prevención y educación sanitaria.

  2. Tula hantavirus isolate with the full-length ORF for nonstructural protein NSs survives for more consequent passages in interferon-competent cells than the isolate having truncated NSs ORF.

    Science.gov (United States)

    Jääskeläinen, Kirsi M; Plyusnina, Angelina; Lundkvist, Ake; Vaheri, Antti; Plyusnin, Alexander

    2008-01-11

    The competitiveness of two Tula hantavirus (TULV) isolates, TULV/Lodz and TULV/Moravia, was evaluated in interferon (IFN) -competent and IFN-deficient cells. The two isolates differ in the length of the open reading frame (ORF) encoding the nonstructural protein NSs, which has previously been shown to inhibit IFN response in infected cells. In IFN-deficient Vero E6 cells both TULV isolates survived equally well. In contrast, in IFN-competent MRC5 cells TULV/Lodz isolate, that possesses the NSs ORF for the full-length protein of 90 aa, survived for more consequent passages than TULV/Moravia isolate, which contains the ORF for truncated NSs protein (66-67 aa). Our data show that expression of a full-length NSs protein is beneficial for the virus survival and competitiveness in IFN-competent cells and not essential in IFN-deficient cells. These results suggest that the N-terminal aa residues are important for the full activity of the NSs protein.

  3. Energy in Sweden. Facts and figures 2004

    International Nuclear Information System (INIS)

    2004-12-01

    Energy in Sweden 2004: Facts and Figures contains the tabular data for most of the diagrams in the main publication. These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. Facts and Figures is available at www.stem.se in pdf- and excel file formats. Since the year 2001 statistics for the period 1983-1998 are revised compared to data for previous editions. With effect from the 2001 edition, statistics are of preliminary character for the two preceding years. Breakdowns into certain types of fuels vary somewhat depending on whether preliminary or final data has been used. Further information about the statistics can be found in Energy in Sweden, chapter 8 Energy Facts.

  4. Health and social inequities in Sweden

    DEFF Research Database (Denmark)

    Diderichsen, Finn

    1990-01-01

    Sweden is one of Europe's most egalitarian countries. The social inequities in living conditions have been gradually reduced to a level that is more equal than in most countries in Europe. Even if general health development has been positive during recent years, data reviewed here indicate...... that there may be adverse effects for some groups which may increase inequities. This article presents results on inequities in health from the Public Health Report of Sweden 1987 and discusses causal mechanisms and implications for health policy....

  5. Introducing Micro-finance in Sweden

    DEFF Research Database (Denmark)

    Barinaga, Ester

    2013-01-01

    The case describes the first year of efforts to introduce microfinance as a tool to work with vulnerable groups in Sweden, more particularly ex-convicts, former drug-addicts and longterm unemployed women of immigrant background. The teaching objective is to discuss whether micro-finance can be seen...

  6. Status and use of PSA in Sweden

    International Nuclear Information System (INIS)

    Knochenhauer, M.

    1996-05-01

    The performance and use of PSA:s in Sweden goes back about two decades. During all of this time, the field of PSA has been developing intensively, both internationally and within Sweden. The latest years have been characterised by an increased use of PSA models and results, and by major extensions of existing PSA models. The aim of this document is to describe PSA in Sweden with respect to development, scope and maturity, as well as to the contents of the analyses and the use of results. PSA activities will be described from the point of view of both the authorities and the utilities. The report gives an overview of the development within the area of PSA in Sweden both its history and current trends. The aim has been to include a reasonable amount of detail, both on the methods and results in PSA:s performed and on the numerous supporting research programs dealing with various aspects of PSA. 39 refs 39 refs

  7. Status and use of PSA in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Knochenhauer, M

    1996-05-01

    The performance and use of PSA:s in Sweden goes back about two decades. During all of this time, the field of PSA has been developing intensively, both internationally and within Sweden. The latest years have been characterised by an increased use of PSA models and results, and by major extensions of existing PSA models. The aim of this document is to describe PSA in Sweden with respect to development, scope and maturity, as well as to the contents of the analyses and the use of results. PSA activities will be described from the point of view of both the authorities and the utilities. The report gives an overview of the development within the area of PSA in Sweden both its history and current trends. The aim has been to include a reasonable amount of detail, both on the methods and results in PSA:s performed and on the numerous supporting research programs dealing with various aspects of PSA. 39 refs 39 refs.

  8. Energy in Sweden. Facts and figures 1999

    International Nuclear Information System (INIS)

    1999-11-01

    This supplement contains the tabular data of most of the diagrams in the main publication (Energy in Sweden 1999, STEM-ET-82-1999). The figures are based on preliminary statistics, and there may be minor differences between similar data in different sections or tables etc. All table headings and notes are given in both Swedish and English

  9. Disturbed security in Norway and Sweden

    Directory of Open Access Journals (Sweden)

    Wojciech Lieder

    2015-12-01

    Full Text Available The content of the article is an attempt to determine the course and consequences of terrorist attacks that took place in 2010 in Sweden and 2011 in Norway. A Comparative Study includes responses of societies and political elites of both countries.

  10. INOPS Survey data report for Sweden

    DEFF Research Database (Denmark)

    Lindholst, Andrej Christian; Severin, Majbritt Christine

    This data report provides statistics on the organization, management and performance of different ways of providing maintenance services within the municipal park and road sector(s) in Sweden. The statistics rely on data collected in the period from May 2015 to June 2015 through an online survey...

  11. Atomoxetine's Effect on Societal Costs in Sweden

    Science.gov (United States)

    Myren, Karl-Johan; Thernlund, Gunilla; Nylen, Asa; Schacht, Alexander; Svanborg, Par

    2010-01-01

    Objective: To compare societal costs between patients treated with atomoxetine and placebo in Sweden. Method: Ninety-nine pediatric ADHD patients were randomized to a 10-week double-blind treatment with atomoxetine (n = 49) or placebo (n = 50). All parents received four sessions of psycho-education. Parents filled out a resource utilization…

  12. Public Dialogue on Science in Sweden.

    Science.gov (United States)

    Dyring, Annagreta

    1988-01-01

    Explains how Sweden has proceeded to popularize science. Addresses topics dealing with policy, the energy debate, booklets with large circulation, computers and society, contacts between schools and research, building up small science centers, mass media, literary quality, children's responsibility, and some of the challenges. (RT)

  13. Consequences in Sweden of the Chernobyl accident

    International Nuclear Information System (INIS)

    Snihs, J.O.

    1986-01-01

    It summarizes the consequences in Sweden of the Chernobyl accident, describes the emergency response, the basis for decisions and countermeasures, the measurement strategies, the activity levels and doses and countermeasures and action levels used. Past and remaining problems are discussed and the major investigations and improvements are given. (author)

  14. The history of nuclear power in Sweden

    International Nuclear Information System (INIS)

    Larsson, K.E.

    1987-01-01

    The nuclear power developments in Sweden are reviewed, from the first initiatives to start research in the area in 1945 to the parliament decision in 1979 to phase out nuclear power by 2010. The article is primarily concerned with the political and R and D management aspects in the field. (L.E.)

  15. Reconsidering School Politics: Educational Controversies in Sweden

    Science.gov (United States)

    Fredholm, Axel

    2017-01-01

    School politics in Sweden has recently moved in a conservative direction, emphasising the importance of conventional school subjects, stronger teacher authority and more discipline in the classroom. At the same time, consensus on the utility of such measures is lacking in the school debate. The conservative approach is often criticised as…

  16. C. h. p. saves fuel in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Daugas, C F

    1979-04-01

    A combined heat and power plant based on a diesel generator to produce 12MW of electricity and 12MW of heat has successfully supplied the town of Skultuna in Sweden during the winter and has saved 3,700t of oil annually.

  17. Yoshio Nakajima. A Japanese Artist from Sweden

    DEFF Research Database (Denmark)

    Ørum, Tania

    2015-01-01

    Yoshio Nakajima is an interesting example of the globalisation of art. His education and early work as an artist took place in his native Japan, but continued in Europe where he has spent more than 30 years, mainly in provincial Sweden....

  18. Mobility of Knowledge as a Recognition Challenge: Experiences from Sweden

    Science.gov (United States)

    Andersson, Per; Fejes, Andreas

    2010-01-01

    This article focuses on the tensions between mobility, knowledge and recognition, and what the impact of migration could be on lifelong education and society. This is discussed with the case of Sweden as the starting point. The main issue in Sweden concerning migration is the admission of refugees. Sweden has had a relatively open policy…

  19. Reply to Comment Clement et al.: (Prevalence of Antibodies against Hantaviruses in Serum and Saliva of Adults Living or Working on Farms in Yorkshire, United Kingdom

    Directory of Open Access Journals (Sweden)

    Lisa J. Jameson

    2014-09-01

    Full Text Available We acknowledge Clement and colleagues for their comments [1] on our paper [2]. We agree that many controversies are being discussed by the hantavirus community, particularly surrounding the interpretation of serological results and the designation of new species and strains. Within this setting, we are grateful for the opportunity to respond to the key factual and methodological points raised by Clements et al. [...

  20. Sickness presenteeism in Norway and Sweden

    Directory of Open Access Journals (Sweden)

    Vegard Johansen

    2013-01-01

    Full Text Available Introduction: Sickness presenteeism (SP refers to the practice of going to work despite illness. This article describes the distribution of SP in Norway and Sweden. It also discusses relations between SP and various work characteristics and personal factors in the two countries. Methods: More than 2500 Norwegian and Swedish workers between 20 and 60 years of age answered a postal questionnaire. The Norwegian and Swedish samples are weighed and representative with regard to both variables of regional background and demography, but the response rate was low. The distribution of SP is measured by frequency (episodes in the previous year and by length (total days of SP in the previous year. This study employed binary and multinomial logistic regression to detect which factors influence the frequency of SP. Results: Fifty-five per cent of the respondents in Norway and Sweden practised SP in the previous year. The frequency of SP episodes is similar in the two countries. Further, respondents with low/medium income, physical work, and managerial responsibilities report SP more often in both countries. Non-western immigrants, the less educated, and those employed by others are overrepresented with SP in Norway. Neither gender nor age had any particular influence. Discussion: In accordance with previous studies, this study among Norwegian and Swedish workers suggests that some SP during a working year may be more common than no SP. Our analyses of determinants of SP present some previously undocumented differences. Divisions between sedentary versus physical work and management versus non-management were important for SP in Norway and Sweden. Moreover, non-western immigrants are overrepresented with SP in Norway, but this pattern does not prevail in Sweden. Some possible causes for non-western immigrants to report more SP are suggested in the article, but we need more research to follow up on the missing correlation between ethnic background and SP in

  1. Hantavirus Public Health outreach effectiveness in three populations: an overview of northwestern New Mexico, Los Santos Panama, and Region IX Chile.

    Science.gov (United States)

    McConnell, Marjorie S

    2014-02-27

    This research compared the effectiveness of Hantavirus Pulmonary Syndrome (HPS) outreach programs in New Mexico, Panama, and Chile. Understanding the role of human demographics, disease ecology, and human behavior in the disease process is critical to the examination of community responses in terms of behavior changes. Attitudes, knowledge, and behavior across three populations were measured through the implementation of a self-administered questionnaire (N = 601). Surveys implemented in Chile and Panama in 2004, followed by northwestern New Mexico in 2008, attempted to assess knowledge and behavior change with respect to hantavirus in high- and lower-risk prevalence areas during endemic periods. While levels of concern over contracting hantavirus were lowest in New Mexico, they were highest in Panama. Respondents in Chile showed mid-level concern and exhibited a tendency to practice proper cleaning methods more than in New Mexico and Panama. This indicates that public health messages appear to be more effective in Chile. However, since negative behavior changes, such as sweeping and vacuuming, occur at some level in all three populations, improved messages should help decrease risk of exposure to HPS.

  2. The triplet repeats of the Sin Nombre hantavirus 5' untranslated region are sufficient in cis for nucleocapsid-mediated translation initiation.

    Science.gov (United States)

    Mir, Mohammad A; Panganiban, Antonito T

    2010-09-01

    Hantavirus nucleocapsid protein (N) can replace the cellular cap-binding complex, eukaryotic initiation factor 4F (eIF4F), to mediate translation initiation. Although N can augment translation initiation of nonviral mRNA, initiation of viral mRNA by N is superior. All members of the Bunyaviridae family, including the species of the hantavirus genus, express either three or four primary mRNAs from their tripartite negative-sense genomes. The 5' ends of the mRNAs contain nonviral heterologous oligonucleotides that originate from endonucleolytic cleavage of cellular mRNA during the process of cap snatching. In the hantaviruses these caps terminate with a 3' G residue followed by nucleotides arising from the viral template. Further, the 5' untranslated region (UTR) of viral mRNA uniformly contains, near the 5' end, either two or three copies of the triplet repeat sequence, UAGUAG or UAGUAGUAG. Through analysis of a panel of mutants with mutations in the viral UTR, we found that the sequence GUAGUAG is sufficient for preferential N-mediated translation initiation and for high-affinity binding of N to the UTR. This heptanucleotide sequence is present in viral mRNA containing either two or three copies of the triplet repeat.

  3. Increased Plasma Cell-Free DNA Level during HTNV Infection: Correlation with Disease Severity and Virus Load

    Directory of Open Access Journals (Sweden)

    Jing Yi

    2014-07-01

    Full Text Available Cell-free DNA (cf-DNA in blood represents a promising DNA damage response triggered by virus infection or trauma, tumor, etc. Hantavirus primarily causes two diseases: haemorrhagic fever with renal syndrome (HFRS and Hantavirus cardiopulmonary syndrome (HCPS, depending on different Hantavirus species. The aim of this study was to evaluate plasma cf-DNA levels in acute phase of HFRS, and to correlate plasma cf-DNA with disease severity and plasma Hanttan virus (HTNV load. We observed the appearance of cf-DNA in 166 plasma samples from 76 HFRS patients: the plasma cf-DNA levels peaked at the hypotensive stage of HFRS, and then decreased gradually. Until the diuretic stage, there was no significant difference in plasma cf-DNA level between patients and the healthy control. Exclusively in the febrile/hypotensive stage, the plasma cf-DNA levels of severe/critical patients were higher than those of the mild/moderate group. Moreover, the plasma cf-DNA value in the early stage of HFRS was correlated with HTNV load and disease severity. In most of the patients, plasma cf-DNA displayed a low-molecular weight appearance, corresponding to the size of apoptotic DNA. In conclusion, the plasma cf-DNA levels were dynamically elevated during HFRS, and correlated with disease severity, which suggests that plasma cf-DNA may be a potential biomarker for the pathogenesis and prognosis of HFRS.

  4. An instructive comparison of Denmark and Sweden CO2 emissions

    International Nuclear Information System (INIS)

    Huffer, E.; Nifenecker, H.

    2007-02-01

    Denmark and Sweden are close neighbors, they have pretty much the same Climate, so that it is interesting to try to understand what makes them so different in their per capita GHG (Green House Gas) emissions from fuel combustion. Indeed, the CO 2 emissions of Denmark and Sweden are practically equal while the population of Sweden is much larger. Thus, the per capita CO 2 emissions of Denmark are 63 % larger than those of Sweden. Denmark resorts heavily to fossil fuels for its production of both its electric power and its industrial heat whereas Sweden resorts to other primary energy sources which are either renewable or do not emit CO 2 . True, Sweden is in a privileged situation for its access to hydro power and to biomass but Denmark could considerably reduce its CO 2 emissions if it were to call on nuclear power as Sweden has been doing. (A.L.B.)

  5. Seroprevalencia de Hantavirus, Rickettsia y Chikungunya en población indígena del municipio de Tuchín, Córdoba

    Directory of Open Access Journals (Sweden)

    Samia Barrera

    Full Text Available Introducción: La vigilancia de las enfermedades transmitidas por vectores es importante para establecer medidas de control en salud pública. Las poblaciones indígenas de Córdoba viven en condiciones geoclimáticas que favorecen la presencia de vectores que podrían permitir la diseminación y aparición de hantavirosis, rickettsiosis y fiebre por el virus Chikungunya. Objetivo: Establecer la seroprevalencia de Hantavirus, Rickettsia sp. y Chikungunya en la población indígena de Tuchín, Córdoba. Materiales y métodos: Se realizó un estudio descriptivo de corte transversal en 190 individuos del resguardo indígena del municipio de Tuchín; el muestreo fue realizado entre agosto y diciembre del 2012. La detección de anticuerpos IgG contra Hantavirus se llevó a cabo con la prueba IgG DxSelectTM (Focus Technologies, EL1600G, California, EE. UU., anticuerpos IgG contra Rickettsia sp. se determinaron por inmunofluorescencia indirecta y se realizó detección de anticuerpos IgG contra el virus Chikungunya mediante ELISA de captura (Nova-Tec, inmunodiagnostica GmbH, CHIG0590, Alemania. Resultados: De 190 sueros analizados, el 5,2% (10/190 fueron positivos para Rickettsia sp. del grupo de la fiebre manchada, para Hantavirus 7 de 87 (8% fueron positivos y no se encontraron positivos para Chikungunya. No se encontraron diferencias significativas (p = 0,05 entre los seropositivos de Hantavirus y Rickettsia sp. para las variables género, edad y ocupación. Conclusiones: Los hallazgos demuestran exposición previa a Rickettsia sp. y a Hantavirus en la población indígena de Tuchín. Los resultados pueden ser útiles para establecer una alerta sobre estas fiebres hemorrágicas. Aunque no se hallaron seropositivos para Chikungunya, este fue el primer trabajo de vigilancia epidemiológica realizado en Colombia sobre este virus.

  6. Spatial-Temporal Distribution of Hantavirus Rodent-Borne Infection by Oligoryzomys fulvescens in the Agua Buena Region--Panama.

    Science.gov (United States)

    Armién, Blas; Ortiz, Paulo Lazaro; Gonzalez, Publio; Cumbrera, Alberto; Rivero, Alina; Avila, Mario; Armién, Aníbal G; Koster, Frederick; Glass, Gregory

    2016-02-01

    Hotspot detection and characterization has played an increasing role in understanding the maintenance and transmission of zoonotic pathogens. Identifying the specific environmental factors (or their correlates) that influence reservoir host abundance help increase understanding of how pathogens are maintained in natural systems and are crucial to identifying disease risk. However, most recent studies are performed at macro-scale and describe broad temporal patterns of population abundances. Few have been conducted at a microscale over short time periods that better capture the dynamical patterns of key populations. These finer resolution studies may better define the likelihood of local pathogen persistence. This study characterizes the landscape distribution and spatio-temporal dynamics of Oligoryzomys fulvescens (O. fulvescens), an important mammalian reservoir in Central America. Information collected in a longitudinal study of rodent populations in the community of Agua Buena in Tonosí, Panama, between April 2006 and December 2009 was analyzed using non-spatial analyses (box plots) and explicit spatial statistical tests (correlograms, SADIE and LISA). A 90 node grid was built (raster format) to design a base map. The area between the nodes was 0.09 km(2) and the total study area was 6.43 km(2) (2.39 x 2.69 km). The temporal assessment dataset was divided into four periods for each year studied: the dry season, rainy season, and two months-long transitions between seasons (the months of April and December). There were heterogeneous patterns in the population densities and degrees of dispersion of O. fulvescens that varied across seasons and among years. The species typically was locally absent during the late transitional months of the season, and re-established locally in subsequent years. These populations re-occurred in the same area during the first three years but subsequently re-established further south in the final year of the study. Spatial autocorrelation analyses indicated local populations encompassed approximately 300-600 m. The borders between suitable and unsuitable habitats were sharply demarcated over short distances. Oligoryzomys fulvescens showed a well-defined spatial pattern that evolved over time, and led to a pattern of changing aggregation. Thus, hot spots of abundance showed a general shifting pattern that helps explain the intermittent risk from pathogens transmitted by this species. This variation was associated with seasonality, as well as anthropogenic pressures that occurred with agricultural activities. These factors help define the characteristics of the occurrence, timing, intensity and duration of synanthropic populations affected by human populations and, consequently, possible exposure that local human populations experience.

  7. Spatial-Temporal Distribution of Hantavirus Rodent-Borne Infection by Oligoryzomys fulvescens in the Agua Buena Region - Panama

    Science.gov (United States)

    Gonzalez, Publio; Cumbrera, Alberto; Rivero, Alina; Avila, Mario; Armién, Aníbal G.; Koster, Frederick; Glass, Gregory

    2016-01-01

    Background Hotspot detection and characterization has played an increasing role in understanding the maintenance and transmission of zoonotic pathogens. Identifying the specific environmental factors (or their correlates) that influence reservoir host abundance help increase understanding of how pathogens are maintained in natural systems and are crucial to identifying disease risk. However, most recent studies are performed at macro-scale and describe broad temporal patterns of population abundances. Few have been conducted at a microscale over short time periods that better capture the dynamical patterns of key populations. These finer resolution studies may better define the likelihood of local pathogen persistence. This study characterizes the landscape distribution and spatio-temporal dynamics of Oligoryzomys fulvescens (O. fulvescens), an important mammalian reservoir in Central America. Methods Information collected in a longitudinal study of rodent populations in the community of Agua Buena in Tonosí, Panama, between April 2006 and December 2009 was analyzed using non-spatial analyses (box plots) and explicit spatial statistical tests (correlograms, SADIE and LISA). A 90 node grid was built (raster format) to design a base map. The area between the nodes was 0.09 km2 and the total study area was 6.43 km2 (2.39 x 2.69 km). The temporal assessment dataset was divided into four periods for each year studied: the dry season, rainy season, and two months-long transitions between seasons (the months of April and December). Results There were heterogeneous patterns in the population densities and degrees of dispersion of O. fulvescens that varied across seasons and among years. The species typically was locally absent during the late transitional months of the season, and re-established locally in subsequent years. These populations re-occurred in the same area during the first three years but subsequently re-established further south in the final year of the study. Spatial autocorrelation analyses indicated local populations encompassed approximately 300–600 m. The borders between suitable and unsuitable habitats were sharply demarcated over short distances. Conclusion Oligoryzomys fulvescens showed a well-defined spatial pattern that evolved over time, and led to a pattern of changing aggregation. Thus, hot spots of abundance showed a general shifting pattern that helps explain the intermittent risk from pathogens transmitted by this species. This variation was associated with seasonality, as well as anthropogenic pressures that occurred with agricultural activities. These factors help define the characteristics of the occurrence, timing, intensity and duration of synanthropic populations affected by human populations and, consequently, possible exposure that local human populations experience. PMID:26894436

  8. Nord Stream, Sweden and Baltic Sea Security

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, Robert L

    2007-03-15

    In June 2006, FOI published the report: Sweden and the NEGP: a Pilot Study of the North European Gas Pipeline and Sweden's Dependence on Russian Energy, a base data report on a topic that FOI considered to be of rising importance. Much has happened since then and the NEGP has changed its name to Nord Stream and submitted an official notification on the intention of realising the project of constructing a gas pipeline from Russia to Germany via the Baltic Sea. The primary aim of this report is to discuss and analyse some of the core aspects of Nord Stream and the pipeline project with regard to the security situation for the Baltic Sea region. The report constitutes an updated version of the previous report. Most of the old report still stands valid, especially concerning the historical survey of Russia's energy policy, but the new report has additional chapters and is broader in scope concerning the consequences of the project

  9. Chlamydia psittaci in birds of prey, Sweden

    Directory of Open Access Journals (Sweden)

    Maria Blomqvist

    2012-05-01

    Full Text Available Background: Chlamydia psittaci is an intracellular bacterium primarily causing respiratory diseases in birds but may also be transmitted to other animals, including humans. The prevalence of the pathogen in wild birds in Sweden is largely unknown. Methods: DNA was extracted from cloacae swabs and screened for C. psittaci by using a 23S rRNA gene PCR assay. Partial 16S rRNA and ompA gene fragments were sequence determined and phylogenies were analysed by the neighbour-joining method. Results and conclusion: The C. psittaci prevalence was 1.3% in 319 Peregrine Falcons and White-tailed Sea Eagles, vulnerable top-predators in Sweden. 16S rRNA and ompA gene analysis showed that novel Chlamydia species, as well as novel C. psittaci strains, are to be found among wild birds.

  10. Nord Stream, Sweden and Baltic Sea Security

    International Nuclear Information System (INIS)

    Larsson, Robert L.

    2007-03-01

    In June 2006, FOI published the report: Sweden and the NEGP: a Pilot Study of the North European Gas Pipeline and Sweden's Dependence on Russian Energy, a base data report on a topic that FOI considered to be of rising importance. Much has happened since then and the NEGP has changed its name to Nord Stream and submitted an official notification on the intention of realising the project of constructing a gas pipeline from Russia to Germany via the Baltic Sea. The primary aim of this report is to discuss and analyse some of the core aspects of Nord Stream and the pipeline project with regard to the security situation for the Baltic Sea region. The report constitutes an updated version of the previous report. Most of the old report still stands valid, especially concerning the historical survey of Russia's energy policy, but the new report has additional chapters and is broader in scope concerning the consequences of the project

  11. The Y2K issue in Sweden

    International Nuclear Information System (INIS)

    Dahlin, G.; Ek, P.; Isaksson, S.; Ericsson, A.M.; Jaernry, C.

    1999-01-01

    The paper overviews the work performed in Sweden on the Y2K issue. It describes in summary how the work is done at the utilities, some lessons learned and the work performed by the regulatory body, the Swedish Power Inspectorate. It discusses as well, how the reporting and accountancy has been changed to meet the Y2K problem at the Swedish State Authority as well as at the Swedish nuclear facilities. There is a section describing the Physical Protection issues

  12. Transportation of radioactive materials in Sweden

    International Nuclear Information System (INIS)

    Ericsson, A.M.

    1979-06-01

    This report is designed to calculate the total risk due to shipping radioactive materials in Sweden. The base case developed is the shipment model that is used now or the best estimate for expected shipments. The model for the calculations and the computer program used has been developed at the Sandia Laboratories, Albuquerque, N.M., USA and is the same that was used for the NUREG-0170 study. The results from the calculations show an annual expected population dose of 30 person-rem due to normal transport conditions. The annual expected dose from accidents were calculated to be between 2.3-20.8 person rem. The higher figure represents the case where plutonium is shipped back to Sweden from reprocessing plants abroad in the form of PuO2 and the lower figure represent the case when plutonium is shipped back in the form of mixed oxide fuel. The total additional population dose in Sweden due to both normal and accident conditions in the transportation of radioactive materials will be 30 - 50 person rem/year. Compared to the natural background radiation that is 8x10 5 person rem per year in Sweden, this figure is very low. If converted to latent cancer fatalities this population dose will add approximately 3.5x10 3 cancers each year. The consequences due to accidents have been calculated and are discussed separately from their probabilities. The most severe accident that was found was an accident involving PuO 2 . This accident would give 82 400 rem as a maximum individual dose and 8.1x10 5 person rem as a population dose. (Auth.)

  13. Citizens and taxation : Sweden in comparative perspective

    OpenAIRE

    Edlund, Jonas

    1999-01-01

    In the contemporary critique of the welfare state a common target is taxation. The consequences of the high levels of taxes collected by the modern state, the critics argue, are slowdown in economic growth, high unemployment, and declining public legitimacy for taxes and state provided welfare. This thesis explores the political support for taxation in Sweden, the epitome of high-tax-society. The thesis consists of one introductory chapter and five journal articles. The first objective of the...

  14. Radon problems in Sweden. Investigations and countermeasures

    International Nuclear Information System (INIS)

    Snihs, J.O.; Ehdwall, H.

    1978-11-01

    For some years radon has been of great concern in Sweden both as a source of occupational exposure in mines and other underground spaces and as a source of radiation exposures in dwellings has lately increased to a considerable extent and appropriate measurements and possible countermeasures are under intensive discussion. The policy and general principles of the supervision especially at work places are described here with a brief description of the progress of the development work on measuring methods. (author)

  15. Evaluating the gender wage gap in Sweden

    OpenAIRE

    Malmberg, Åsa

    2007-01-01

    Using mainly quantile regressions, this paper evaluates the gender wage gap throughout the conditional wage distribution in Sweden. The gender wage is found to increase at the upper tail of the wage distribution, indicating an enforcement of the glass ceiling effect recorded in earlier studies. The results also indicate that the earlier noted trend of diminishing wage differences at the bottom of the wage distribution now is turning. The increase of overall wage inequalities coincides with a ...

  16. Climate Change and Respiratory Infections.

    Science.gov (United States)

    Mirsaeidi, Mehdi; Motahari, Hooman; Taghizadeh Khamesi, Mojdeh; Sharifi, Arash; Campos, Michael; Schraufnagel, Dean E

    2016-08-01

    The rate of global warming has accelerated over the past 50 years. Increasing surface temperature is melting glaciers and raising the sea level. More flooding, droughts, hurricanes, and heat waves are being reported. Accelerated changes in climate are already affecting human health, in part by altering the epidemiology of climate-sensitive pathogens. In particular, climate change may alter the incidence and severity of respiratory infections by affecting vectors and host immune responses. Certain respiratory infections, such as avian influenza and coccidioidomycosis, are occurring in locations previously unaffected, apparently because of global warming. Young children and older adults appear to be particularly vulnerable to rapid fluctuations in ambient temperature. For example, an increase in the incidence in childhood pneumonia in Australia has been associated with sharp temperature drops from one day to the next. Extreme weather events, such as heat waves, floods, major storms, drought, and wildfires, are also believed to change the incidence of respiratory infections. An outbreak of aspergillosis among Japanese survivors of the 2011 tsunami is one such well-documented example. Changes in temperature, precipitation, relative humidity, and air pollution influence viral activity and transmission. For example, in early 2000, an outbreak of Hantavirus respiratory disease was linked to a local increase in the rodent population, which in turn was attributed to a two- to threefold increase in rainfall before the outbreak. Climate-sensitive respiratory pathogens present challenges to respiratory health that may be far greater in the foreseeable future.

  17. Uranium recovery in Sweden. History and perspective

    International Nuclear Information System (INIS)

    Hultgren, Aa.; Olsson, G.

    1993-08-01

    In 1945 the potential of nuclear energy for military and peaceful purpose had initiated a strong interest in Sweden to establish a national programme in the field. The Atomic Energy Committee was formed at the end of 1945 and charged the Research Institute of National Defence in January 1946 with the test to investigate possibilities of uranium recovery in Sweden. AB Atomenergi, a semi-state owned body, was formed in November 1947 to take charge of nuclear energy related research and development. The search for and the recovery of uranium from indigenous resources became a dominant objective over the first years of the company. The report gives a broad overview of the efforts to establish a national uranium fuel supply programme in Sweden from the early days of the postwar years of the 1940s. Process and plant development, plant operations at Kvarntorp and Ranstad, and the development of the uranium supply policy are presented against a background of the nuclear power development in the country. The nuclear weapons debate and the decision to sign the non proliferation treaty in 1968 are briefly reported. Special attention has been given an account of the technical development and the various projects related to the Ranstad plant and its final restoration in the 1980s

  18. Consequences in Sweden of the Chernobyl accident

    International Nuclear Information System (INIS)

    Haegg, Conny.

    1990-01-01

    The radiation doses to man in Sweden due to the Chernobyl accident originate mainly from external irradiation from deposited radionuclides and internal irradiation from consumption of radioactively contaminated food stuffs. Inhalation and external irradiation from the passing cloud give only a minor contribution to the total dose. As an average for the Swedish population the individual radiation dose during the first year amounts to about 0.1 mSv, i.e. 10% of the natural background radiation. In the most contaminated areas, however, the individual dose may become 30 times higher than the average dose. The dose committed over 50 years has estimated to be about six times as high as the first year dose. The collective dose for the Swedish population has been estimated to about 1300 manSv the first year after the accident and the corresponding dose over 50 years to 5000 to 7000 manSv. This could lead to 100 to 200 extra fatal cancers. Furthermore, no damages on man that can be related to Chernobyl fallout, e.g. pre-natal effects, have so far been observed in Sweden. Shortly after the accident, several research projects were initiated in Sweden in order to follow the distribution of radionuclides in the aquatic and terrestrial environment. The results which in many cases are preliminary, shows that the recovery of the ecosystem will take several decades. (author)

  19. Cases of human brucellosis in Sweden linked to Middle East and Africa.

    Science.gov (United States)

    Garofolo, Giuliano; Fasanella, Antonio; Di Giannatale, Elisabetta; Platone, Ilenia; Sacchini, Lorena; Persiani, Tiziana; Boskani, Talar; Rizzardi, Kristina; Wahab, Tara

    2016-05-17

    Human brucellosis cases are still reported each year in Sweden despite eradication of the disease in animals. Epidemiological investigation has never been conducted to trace back the source of human infection in the country. The purpose of the study was to identify the source of infection for 16 human brucellosis cases that occurred in Sweden, during the period 2008-2012. The isolates were identified as Brucella melitensis and MLVA-16 genotyping revealed 14 different genotypes of East Mediterranean and Africa lineages. We also reported one case of laboratory-acquired brucellosis (LAB) that was shown to be epidemiological linked to one of the cases in the current study. Brucella melitensis was the only species diagnosed, confirming its highest zoonotic potential in the genus Brucella, and MLVA-16 results demonstrated that the cases of brucellosis in Sweden herein investigated, are imported and linked to travel in the Middle East and Africa. Due to its zoonotic concerns, any acute febrile illness linked to recent travel within those regions should be investigated for brucellosis and samples should be processed according to biosafety level 3 regulations.

  20. Prone Position Ventilation Used during a Transfer as a Bridge to Ecmo Therapy in Hantavirus-Induced Severe Cardiopulmonary Syndrome

    Directory of Open Access Journals (Sweden)

    R. Cornejo

    2013-01-01

    Full Text Available Background. Transport of critically ill patients is a complex issue. We present a case using prone positioning as a bridge to extracorporeal membrane oxygenation (ECMO, performed by a critical retrieval team from a university hospital. Case Report. A 28-year-old male developed fever, progressive respiratory failure, and shock. He was admitted to ICU from a public hospital, and mechanical ventilation was begun, but clinical response was not adequate. ECMO was deemed necessary due to severe respiratory failure and severe shock. A critical retrieval team of our center was assembled to attempt transfer. Prone positioning was employed to stabilize and transfer the patient, after risk-benefit assessment. Once in our hospital, ECMO was useful to resolve shock and pulmonary edema secondary to Hantavirus cardiopulmonary syndrome. Finally, he was discharged with normal functioning. Conclusion. This case exemplifies the relevance of a retrieval team and bridge therapy. Prone positioning improves oxygenation and is safe to perform as transport if performed by a trained team as in this case. Preparation and organization is necessary to improve outcomes, using teams and organized networks. Catastrophic respiratory failure and shock should not be contraindications to transferring patients, but it must be done with an experienced team.

  1. Leaving Sweden behind: Gains in life expectancy in Canada.

    Science.gov (United States)

    Auger, Nathalie; Le Serbon, Emilie; Rostila, Mikael

    2015-06-01

    Sweden and Canada are known for quality of living and exceedingly high life expectancy, but recent data on how these countries compare are lacking. We measured life expectancy in Canada and Sweden during the past decade, and identified factors responsible for changes over time. We calculated life expectancy at birth for Canada and Sweden annually from 2000 to 2010, and determined the ages and causes of death responsible for the gap between the two countries using Arriaga's method. We determined how population growth, ageing, and mortality influenced the number of deaths over time. During 2000-2010, life expectancy in Canada caught up with Sweden for men, and surpassed Sweden by 0.4 years for women. Sweden lost ground owing to a slower reduction in circulatory and tumour mortality after age 65 years compared with Canada. Nonetheless, population ageing increased the number of deaths in Canada, especially for mental and nervous system disorders. In Sweden, the number of deaths decreased. In only one decade, life expectancy in Canada caught up and surpassed Sweden due to rapid improvements in circulatory and tumour mortality. Population ageing increased the number of deaths in Canada, potentially stressing the health care system more than in Sweden. © 2015 the Nordic Societies of Public Health.

  2. Composition of atmospheric precipitation in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Emanuelsson, A; Eriksson, E; Egner, H

    1954-01-01

    Preliminary charts are presented based on two years of data, to demonstrate the geographic distribution over Sweden of the annual amounts of Na, Cl, K, Ca, NH/sub 3//sup -n/, and NO/sub 3//sup -n/ brought to the surface of the earth by precipitation. The ratios of these total amounts to the total amounts of Na deposited during the same time interval are shown to possess systematic geographic distribution patterns. Comparisons are made between these ratios and the corresponding quantities in sea water. The investigation is now being resumed to provide additional data from a larger number of stations and for longer time periods.

  3. Industrial action in Sweden - a new pattern?

    OpenAIRE

    Lindberg, Henrik

    2011-01-01

    The paper studies the modern conflict patterns and conflict dimensions in Sweden 1993-2005. The aim is to trace and interpret the new patterns and dimensions of labour market conflict by collecting and compiling strike data from the National Conciliation Office, (1993-99) and the National Mediation Office (2000-2005). On the whole, strike activity has decreased steadily from the 1980s and onwards and in large parts of the Swedish labour market conflicts are very rare. A few small un-ions orga...

  4. Buildings with enhanced radioactivity in Sweden

    International Nuclear Information System (INIS)

    Swedjemark, G.A.

    1980-12-01

    Enhanced radon/radon daughter concentrations indoors have been found in some houses in Sweden, especially in combination with low air exchange rates. The radon sources have been found to be some types of building materials, some types of filling materials, some types of ground and any combination of these sources. The radon source may also be radon-rich tap water. The same types of building materials also give an enhanced gamma radiation level. In all houses, both lower and higher concentrations of radon than the average levels given here have been found in individual rooms and with single measurements. (author)

  5. PRE-HOSPITAL EMERGENCY CARE IN SWEDEN

    Directory of Open Access Journals (Sweden)

    Ulf BJÖRNSTIG

    2004-01-01

    In Sweden (9 million inhabitants, a sparsely populated country with sometimes long transportation distances to the nearest trauma hospital, 800 ambulances, 7 ambulance helicopters and 3–5 fixed wing ambulance aircraft are the available transport resources. In case of a mass casualty or disaster situation, inside or outside the country, a governmental project (Swedish National Medevac aims to convert a passenger aircraft from Scandinavian Airlines System (SAS to a qualified medical resource for long distance transport, with capacity to nurse six intensive care patients and an additional 6–20 lieing or seated patients during transport.

  6. Country policy profile - Sweden. October 2014

    International Nuclear Information System (INIS)

    2014-10-01

    The main support mechanism for electricity from RES is a quota system that is based on a certificate trading system. Furthermore, tax incentives are in place and PV installations are subsidised with grants. Promotion of heating from RES is mainly promoted through tax exemptions. Households may deduct investments of renewable energy heating installations replacing heating systems based on fossil fuels from tax. Heating from RES further benefits from an exemption of various taxes, as carbon dioxide taxes on supply, import and production of fossil fuels for heating purposes, which apply for fossil fuels (Source, RES LEGAL Europe, www.res-legal.eu/search-by-country/sweden/)

  7. Household energy demand. Empirical studies concerning Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Dargay, J; Lundin, A

    1978-06-01

    This paper investigates the effects of energy policy on households in Sweden and provides the material necessary for evaluation of current and proposed energy-conservation measures. Emphasis is placed on the impact of enery taxation or price changes on household demand for electricity, heating oil, and gasoline and the consequences of such measures for income distribution. The results of the Swedish studies of household demand for heating oil and gasoline indicate that price changes can have a considerable long run impact on fuel utilization. In the short run, price responsiveness is notably reduced, but it is nevertheless of consequence for energy demand.

  8. National Debate and Public Confidence in Sweden

    International Nuclear Information System (INIS)

    Lindquist, Ted

    2014-01-01

    Ted Lindquist, coordinator of the Association of Swedish Municipalities with Nuclear Facilities (KSO), closed the first day of conferences. He showed what the nuclear landscape was in Sweden, and in particular that through time there has been a rather good support from the population. He explained that the reason could be the confidence of the public in the national debate. On a more local scale, Ted Lindquist showed how overwhelmingly strong the support was in towns where the industry would like to operate long-term storage facilities

  9. This is how we manage Sweden`s radioactive waste. Activities 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    SKB operates systems and facilities for the management and final disposal of spent nuclear fuel and other radioactive waste in Sweden. SKB has conducted extensive R, D and D work with regard to constructing a spent fuel encapsulation plant and a deep repository in crystalline bedrock. This annual report treats all the different activities without going into technical details.

  10. Domestic gender equality and childbearing in Sweden

    Directory of Open Access Journals (Sweden)

    Frances Goldscheider

    2013-12-01

    Full Text Available Background: Sweden, which is among the most gender-equal societies in the world, combines 'modern' family patterns such as unmarried cohabitation, delayed parenthood, high maternal labor force participation, and high break-up rates - all usually linked with low birth rates - with relatively high fertility. Sweden also has a high level of shared parental responsibility for home and children. Objective: After decades of late 20th century research showing that increasing gender equality in the workplace was linked with lower fertility, might gender equality in the home increase fertility? Methods: Using data from the Swedish Young Adult Panel Study (YAPS, we use Cox regression to examine the effects on first, second, and third births of 1 holding attitudes about sharing equally in the care of the home and children, and 2 actual sharing in these domestic tasks. Results: Our analysis shows that, measuring attitudes before the transition to parenthood and actual practice four years later, it is inconsistency between sharing attitudes and the actual division of housework that reduces the likelihood of continued childbearing, especially on second births among women. Conclusions: As women are most likely to confront an inconsistent situation, with egalitarian ideals in a household without equal sharing, it is clear that having a partner who does not share housework is depressing Swedish fertility.

  11. Space education in Kiruna, Northern Sweden

    Directory of Open Access Journals (Sweden)

    I. Sandahl

    2005-01-01

    Full Text Available The town of Kiruna in the north of Sweden has a concentration of space activities and space research with, for example, the Swedish Institute of Space Physics, Esrange, the ESA Salmijärvi satellite station, and EISCAT (European Incoherent Scatter Radar Scientific Association. The Department of Space Science is a joint department between the two most northern universities in Sweden, Luleå University of Technology and Umeå University in collaboration with the Swedish Institute of Space Physics. It offers a range of education programmes in the space field. There are bachelor and master programmes in space engineering, and a bridging programme for students without a science background from secondary school. The Department also contributes to courses for teachers, Ph.D. courses and secondary school level courses. One master´s program and a three week summer course are given entirely in English and welcome international students. Thanks to good cooperation with Esrange students can build and fly experiments on high altitude balloons and sounding rockets and also take a large responsibility for the management of the projects. Close interaction with research and industry is an important part of the education.

  12. Situation of nuclear power generation in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Sandstroem, S [Swedish Atomic Forum

    1978-01-01

    In Sweden, nuclear power generation was received initially favorably. In the end of 1960s, however, nuclear power generation got involved in the activities of environment preservation. Then, political parties became opposed to nuclear power generation, and now, the need of nuclear power generation itself is regarded as questionable. In the general election in 1976, the Government opposing the nuclear power generation won. As the result, the conditional nuclear power development law and the energy committee were set up. The committee composed of parliament members, experts, and representatives of enterprises and trade unions is to submit its report so that the parliament can prepare a new energy program in the fall of 1978. Meanwhile, the nuclear fuel safety project formed newly has studied to satisfy the conditions of the law. In Sweden, which has developed nuclear reactors independently from the technology of USA, the oppositions are on the decrease, however. It is awaited what decision will be made by the Government in this fall.

  13. Sweden: Combining childbearing and gender equality

    Directory of Open Access Journals (Sweden)

    Eva Bernhardt

    2008-07-01

    Full Text Available Sweden is the forerunner of the Second Demographic Transition. Fertility trends have fluctuated greatly since the 1960s, and the 1990s showed both European-highest and lowest-ever-in-Sweden levels, while the cohort pattern has been relatively stable. Period fluctuations have been accompanied by a postponement of entering committed partnerships and parenthood as well as an increasing instability of family relationships. The awareness and the availability of effective contraceptives have been extensive since the mid-1970s, the year the liberal abortion law was introduced. Post-modern values are dominant in this highly secularized society, but ideal family size is among the highest in the European Union, and childlessness has remained at a relatively low level. Ethnic diversification has increased over time, with about one-fifth of the population having a 'foreign background' in the early 2000s. The level of female labor-force participation is the highest in Europe (although mothers of pre-schoolers often work part-time, and young women are just as highly educated as men. Family policies, based on the principle of equality across social groups and gender, seem to play an important role in keeping fertility relatively high. In combination with other factors, family policies also play a role in the fluctuations of fertility rates, as eligibility to parental-leave and benefits as well as the availability of public childcare are linked to parents' labor-force attachment.

  14. Sweden to host a new neutron source

    CERN Multimedia

    Anaïs Schaeffer

    2012-01-01

    The first European neutron source, currently under development, should commence operations by the end of this decade. Its aim: to produce beams of neutrons that can penetrate into the heart of matter without damaging it and reveal its secrets.   An artist's impression of what the ESS should look like in 2019. At the southern end of Sweden, a town called Lund is preparing for the arrival of the world's most powerful neutron source: the European Spallation Source (ESS). Construction is scheduled to start at the beginning of next year, and the facility is expected to become operational by 2019, when it will produce its first neutron beams. “The ESS is the result of an idea that began 20 years ago!” underlines Mats Lindroos, in charge of the ESS Accelerator Division. “Today, 17 European countries support the project, including Sweden, Denmark and Norway, who together account for 50% of the construction funding.” The ESS, whose design is al...

  15. Nord Stream, Sweden and Baltic Sea Security

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, Robert L.

    2007-03-15

    In June 2006, FOI published the report: Sweden and the NEGP: a Pilot Study of the North European Gas Pipeline and Sweden's Dependence on Russian Energy, a base data report on a topic that FOI considered to be of rising importance. Much has happened since then and the NEGP has changed its name to Nord Stream and submitted an official notification on the intention of realising the project of constructing a gas pipeline from Russia to Germany via the Baltic Sea. The primary aim of this report is to discuss and analyse some of the core aspects of Nord Stream and the pipeline project with regard to the security situation for the Baltic Sea region. The report constitutes an updated version of the previous report. Most of the old report still stands valid, especially concerning the historical survey of Russia's energy policy, but the new report has additional chapters and is broader in scope concerning the consequences of the project

  16. Knowledge and practices about hantavirus pulmonary syndrome in a cluster of Japanese communities in Argentina Conocimientos y prácticas relacionados con el síndrome pulmonar por hantavirus en un conglomerado de comunidades japonesas en Argentina

    Directory of Open Access Journals (Sweden)

    Kuniaki Suzuki

    2009-02-01

    Full Text Available OBJECTIVES: To provide information on hantavirus pulmonary syndrome (HPS knowledge and practices among a cluster of the rural Japanese communities near La Plata in central Ar gentina, an area with confirmed HPS cases. Particular emphasis was placed on testing the hy pothesis that there would be differences between household use of HPS prevention measures based on the head-of-household's knowledge of HPS. METHODS: A questionnaire was designed in three sections: (1 household demographic char acteristics, (2 HPS knowledge, and (3 HPS preventive measures. Questionnaires were given to the household head or other adult representing the household at an HPS prevention semi nar sponsored by the Japanese Association of La Plata in February 2007. Total HPS knowl edge scores were dichotomized into high (equal to or more than the median knowledge score and low (less than the median. Differences between the two household groups were catego rized, according to the degree of HPS knowledge, and analyzed. RESULTS: The 86 households that responded accounted for about 72% of the total study households in the area. The median knowledge score of 5 (range: 0-9, of 10 divided the study households into two groups: high knowledge score group (n = 40 and low knowledge score group (n = 46. The findings suggest an association between a household's accurate HPS knowledge and its respective use of HPS preventive measures. CONCLUSION: The findings of the study have important implications for taking further steps toward improved HPS management and prevention strategies.OBJETIVOS: Documentar los conocimientos y las prácticas relacionadas con el síndrome pulmonar por hantavirus (SPH en un conglomerado de comunidades rurales japonesas cerca de La Plata, en la parte central de Argentina, una zona con casos confirmados de SPH. Se hizo hincapié especial en probar la hipótesis de que habría diferencias en el empleo de medidas preventivas contra el SPH en los hogares según el

  17. New Forms of Youth Participation and Work in Sweden.

    Science.gov (United States)

    Hartmann, Jurgen

    1985-01-01

    Surveys past and current youth employment and social participation programs in Sweden. Maintains that while these were effective in giving Sweden one of the lowest youth unemployment rates among market-economy nations, more must be done to ensure meaningful social participation of youth in the community. (JDH)

  18. Occupational doses and ALARA - recent developments in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Godas, T.; Viktorsson, C. [Swedish Radiation Protection Institute, Stockholm (Sweden)

    1995-03-01

    Sweden has traditionally experienced very slow doses to workers in the nuclear industry. However, this trend has since last year been broken mainly due to significant maintenance and repair work. This paper will describe occupational dose trends in Sweden and discuss actions that are being implemented to control this new situation.

  19. Evaluation of Strategies to Control a Potential Outbreak of Foot-and-Mouth Disease in Sweden

    DEFF Research Database (Denmark)

    Dórea, Fernanda C.; Nöremark, Maria; Widgren, Stefan

    2017-01-01

    of enforcement of interventions, was assessed. With the estimated currently available resources, an FMD outbreak in Sweden is expected to be controlled (i.e., last infected herd detected) within 3 weeks of detection in any evaluated scenario. The density of farms in the area where the epidemic started would have...... little impact on the time to control the outbreak, but spread in high density areas would require more surveillance resources, compared to areas of lower farm density. The use of vaccination did not result in a reduction in the expected number of infected herds. Preemptive depopulation was able to reduce...... the number of infected herds in extreme scenarios designed to test a combination of worst-case conditions of virus introduction and spread, but at the cost of doubling the number of herds culled. This likely resulted from a combination of the small outbreaks predicted by the spread model, and the high...

  20. General equilibrium effects of increasing carbon taxes in Sweden

    International Nuclear Information System (INIS)

    Harrison, G.W.; Kristroem, B.

    1997-01-01

    Sweden was one of the first countries to introduce carbon taxes, and is currently evaluating further carbon taxes. The authors were asked to advise a government commission charged with undertaking the official Swedish evaluation. We did so by constructing and simulating a computable general equilibrium model of Sweden. In this report, the carbon tax debate in Sweden is first reviewed, then our model is described and the main results presented. The conclusion from the cost-benefit analysis is clear, the benefits of increasing the carbon tax in Sweden are a tiny fraction of the costs that consumers must pay in the form of higher prices and reduced incomes. Although we do not put much credence in the gross benefit numbers, they do serve to highlight the basis of our conclusion that carbon tax increases are not currently justifiable in Sweden. 35 refs., 13 tabs

  1. General equilibrium effects of increasing carbon taxes in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, G W [South Carolina Univ., Columbia, SC (United States). Dept. of Economics, College of Business Administration; Kristroem, B [Swedish Univ. of Agricultural Sciences, Umeaa (Sweden). Dept. of Forest Economics

    1997-09-01

    Sweden was one of the first countries to introduce carbon taxes, and is currently evaluating further carbon taxes. The authors were asked to advise a government commission charged with undertaking the official Swedish evaluation. We did so by constructing and simulating a computable general equilibrium model of Sweden. In this report, the carbon tax debate in Sweden is first reviewed, then our model is described and the main results presented. The conclusion from the cost-benefit analysis is clear, the benefits of increasing the carbon tax in Sweden are a tiny fraction of the costs that consumers must pay in the form of higher prices and reduced incomes. Although we do not put much credence in the gross benefit numbers, they do serve to highlight the basis of our conclusion that carbon tax increases are not currently justifiable in Sweden. 35 refs., 13 tabs.

  2. Liver and gallbladder cancer in immigrants to Sweden.

    Science.gov (United States)

    Hemminki, Kari; Mousavi, Seyed Mohsen; Brandt, Andreas; Ji, Jianguang; Sundquist, Jan

    2010-03-01

    The changes of cancer incidence upon immigration can be used as an estimator of environmental influence on cancer risk. We studied site-specific liver and biliary cancers in first-generation immigrants to Sweden with an aim to search for aetiological clues and to find evidence for indigenous incidence rates. We used the nation-wide Swedish Family-Cancer Database to calculate standardised incidence ratios (SIRs) in immigrants compared to native Swedes. A total of 1428 cancers were identified in immigrants whose median ages (years) at immigration were 27 for men and 26 for women and whose median diagnostic ages were 64 and 66, respectively. The highest SIRs of 6.7 for primary liver cancer were observed for men from East Asia and sub-Saharan Africa. Increased SIRs were recorded for male immigrants from previous Yugoslavia (1.78), Southern Europe (2.91), Turkey (2.15) and Asian Arab countries (2.89). For gallbladder cancer, only women from the Indian subcontinent (3.84) and Chile (2.34) had increased risk while some Northern European immigrants showed decreased risks. Primary liver cancer was increased in immigrants from endemic regions of hepatitis B virus infection but also from large regions lacking cancer incidence data, North Africa, Asian Arab countries, Turkey and previous Yugoslavia; these are probably intermediary risk regions for this infection. The consideration of these regions as risk areas would justify active diagnostic and vaccination programs. The increase in gallbladder cancer in Chileans and Indians suggests that some persistent damage was inflicted before emigration, characterisation of which will be a challenge for aetiological studies. Copyright 2009 Elsevier Ltd. All rights reserved.

  3. Damage by pathogens and insects to Scots pine and lodgepole pine 25 years after reciprocal plantings in Canada and Sweden

    OpenAIRE

    Fries, Anders

    2017-01-01

    A combined species - provenance - family experiment with Scots pine and lodgepole pine was planted in Canada and Sweden. One aim of the experiment was to evaluate the two species' sensitivities to pathogens and insects 25 years after establishment in their non-native continents. In Canada, Scots pine had better average survival than lodgepole pine, but survival rates among trees from the best seed-lots were equal. In Canada only western gall rust infected Scots pine to some extent, and mounta...

  4. An amino-terminal segment of hantavirus nucleocapsid protein presented on hepatitis B virus core particles induces a strong and highly cross-reactive antibody response in mice

    International Nuclear Information System (INIS)

    Geldmacher, Astrid; Skrastina, Dace; Petrovskis, Ivars; Borisova, Galina; Berriman, John A.; Roseman, Alan M.; Crowther, R. Anthony; Fischer, Jan; Musema, Shamil; Gelderblom, Hans R.; Lundkvist, Aake; Renhofa, Regina; Ose, Velta; Krueger, Detlev H.; Pumpens, Paul; Ulrich, Rainer

    2004-01-01

    Previously, we have demonstrated that hepatitis B virus (HBV) core particles tolerate the insertion of the amino-terminal 120 amino acids (aa) of the Puumala hantavirus nucleocapsid (N) protein. Here, we demonstrate that the insertion of 120 amino-terminal aa of N proteins from highly virulent Dobrava and Hantaan hantaviruses allows the formation of chimeric core particles. These particles expose the inserted foreign protein segments, at least in part, on their surface. Analysis by electron cryomicroscopy of chimeric particles harbouring the Puumala virus (PUUV) N segment revealed 90% T = 3 and 10% T = 4 shells. A map computed from T = 3 shells shows additional density splaying out from the tips of the spikes producing the effect of an extra shell of density at an outer radius compared with wild-type shells. The inserted Puumala virus N protein segment is flexibly linked to the core spikes and only partially icosahedrally ordered. Immunisation of mice of two different haplotypes (BALB/c and C57BL/6) with chimeric core particles induces a high-titered and highly cross-reactive N-specific antibody response in both mice strains

  5. Climate impact from peat utilisation in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Uppenberg, S.; Zetterberg, L.; Aahman, M.

    2001-08-01

    The climate impact from the use of peat for energy production in Sweden has been evaluated in terms of contribution to atmospheric radiative forcing. This was done by attempting to answer the question 'What will be the climate impact if one would use 1 m{sup 2} of mire for peat extraction during 20 years?'. Two different methods of after-treatment were studied: afforestation and restoration of wetland. The climate impact from a peatland - wetland energy scenario and a peatland - forestry energy scenario was compared to the climate impact from coal, natural gas and forest residues. Sensitivity analyses were performed to evaluate which parameters that are important to take into consideration in order to minimize the climate impact from peat utilisation.

  6. Documents and legal texts: Australia, Germany, Sweden

    International Nuclear Information System (INIS)

    Anon.

    2012-01-01

    Australia: National Radioactive Waste Management Act 2012 No. 29, 2012 (An Act to make provision in relation to the selection of a site for, and the establishment and operation of, a radioactive waste management facility, and for related purposes). Germany: Act on the Peaceful Utilisation of Atomic Energy and the Protection against its Hazards (Atomic Energy Act) of 23 December 1959, as amended and promulgated on 15 July 1985, last amendment by the Act of 8 November 2011. Sweden: The Swedish Radiation Safety Authority's regulations concerning clearance of materials, rooms, buildings and land in practices involving ionising radiation (Swedish Radiation Safety Authority Regulatory Code issued on 20 October 2011, Published on 2 November 2011); The Swedish Radiation Safety Authority's general advice on the application of the regulations concerning clearance of materials, rooms, buildings and land in practices involving ionising radiation (issued on 20 October 2011)

  7. Time trends in human fecundability in Sweden

    DEFF Research Database (Denmark)

    Scheike, Thomas H; Rylander, Lars; Carstensen, Lisbeth

    2008-01-01

    ,000 primiparous women 20 years of age and older in the nationwide Swedish Medical Birth Registry from 1983 through 2002. This age restriction led to an exclusion of 10% of primiparous pregnancies. Subfertility (TTP > or =1 year) was analyzed as a function of maternal age, calendar time at initiation of attempt...... increased with age, except that for women in their late 1930s, an apparent decrease was observed, particularly among the early cohorts. CONCLUSION: We found decreasing subfertility over time. We speculate that these patterns might be related to a Sweden-specific decrease over time in sexually transmitted...... diseases, to changes in sexual behavior induced by socioeconomic conditions, or to broader biologic or educational trends....

  8. Reprocessing in Sweden: History and perspective

    International Nuclear Information System (INIS)

    Hultgren, Aa.; Oesterlund, C.G.

    1990-10-01

    Against the background of nuclear power development and installation in Sweden an overview is presented of the parallel domestic development of the reprocessing of spent nuclear fuel. The original selection of the natural uranium - heavy water reactor in the 1950s included spent fuel reprocessing and recycle, and process and plant studies were performed to that end. The switch to light water reactors in the 1960s did not change the planning to recycle; however, the participation in the Eurochemic undertaking, and the delay in the nuclear programme stopped further domestic development work. A number of governmental committee investigations in the 1970s on the radioactive waste issue and, above all, the decision to phase out nuclear power by 2010, after a referendum following the TMI-accident, finally resulted in a decision to plan only for direct disposal of spent nuclear fuel. This policy still prevails. (42 refs.)

  9. Media use in distance education in Sweden

    Directory of Open Access Journals (Sweden)

    Norman F. Davies

    2013-02-01

    Full Text Available This article gives an overview of distance language teaching which developed rapidly in Sweden after the Second World War. It argues that so far little use has been made of technical aids and that the computer as such is still a stranger both to the language teacher and the student. The writer concludes that perhaps the time has come for a technical revolution amongst Arts students. Met hierdie artikel word 'n oorsig gegee oor afstandsonderrig-spesifiek wat tale betref-soos dit in Swede ontwikkel het na die Tweede Wereldoorlog. Daar word op gewys dat tot dusver min gebruik gemaak is van tegniese hulpmiddels en dat vera! die rekenaar onderbenut is. Die skrywer sluit met die gedagte dat die tyd moontlik ryp is vir 'n tegnologiese rewolusie"in die geledere van die Lettere en Wysbegeerte.

  10. Selling eugenics: the case of Sweden.

    Science.gov (United States)

    Bjorkman, Maria; Widmalm, Sven

    2010-12-20

    This paper traces the early (1910s to 1920s) development of Swedish eugenics through a study of the social network that promoted it. The eugenics network consisted mainly of academics from a variety of disciplines, but with medicine and biology dominating; connections with German scientists who would later shape Nazi biopolitics were strong. The paper shows how the network used political lobbying (for example, using contacts with academically accomplished MPs) and various media strategies to gain scientific and political support for their cause, where a major goal was the creation of a eugenics institute (which opened in 1922). It also outlines the eugenic vision of the institute's first director, Herman Lundborg. In effect the network, and in particular Lundborg, promoted the view that politics should be guided by eugenics and by a genetically superior elite. The selling of eugenics in Sweden is an example of the co-production of science and social order.

  11. Climate impact from peat utilisation in Sweden

    International Nuclear Information System (INIS)

    Uppenberg, S.; Zetterberg, L.; Aahman, M.

    2001-08-01

    The climate impact from the use of peat for energy production in Sweden has been evaluated in terms of contribution to atmospheric radiative forcing. This was done by attempting to answer the question 'What will be the climate impact if one would use 1 m 2 of mire for peat extraction during 20 years?'. Two different methods of after-treatment were studied: afforestation and restoration of wetland. The climate impact from a peatland - wetland energy scenario and a peatland - forestry energy scenario was compared to the climate impact from coal, natural gas and forest residues. Sensitivity analyses were performed to evaluate which parameters that are important to take into consideration in order to minimize the climate impact from peat utilisation

  12. Physical protection philosophy and techniques in Sweden

    International Nuclear Information System (INIS)

    Dufva, B.

    1988-01-01

    The circumstances for the protection of nuclear power plants are special in Sweden. A very important factor is that armed guards at the facilities are alien to the Swedish society. They do not use them. The Swedish concept of physical protection accepts that the aggressor will get into the facility. With this in mind, the Swedish Nuclear Power Inspectorate (SKI) has established the policy that administrative, technical, and organizational measures will be directed toward preventing an aggressor from damaging the reactor, even if he has occupied the facility. In addition, the best conditions possible shall be established for the operator and the police to reoccupy the plant. The author believes this policy is different from that of many other countries. Therefore, he focusses on the Swedish philosophy and techniques for the physical protection of nuclear power plants

  13. Wind Power Statistics Sweden 2009; Vindkraftstatistik 2009

    Energy Technology Data Exchange (ETDEWEB)

    2010-04-15

    In 2009, wind power produced 2.5 TWh, an increase of 26 percent over the previous year. Throughout the period 2003-2009 has production of electricity from wind power almost quadrupled. Sweden's total net production of electricity amounted, according to provisional statistics for 2009, to 133.7 TWh. The year 2007 wind energy's share passed 1.0 percent of total net production of electricity for the first time. In 2008 the proportion was 1.4 percent, and in 2009 to almost 1.9 percent of total net production. Total installed power 2009 was 1448 MW and the number of plants was 1359, an inckW{sub pse} with 363 MW and 198 resp. from 2008. In 2009, there were three main support system for wind power in Sweden: the certificate system; the wind pilot project; and the environmental bonus. The electricity certificate system is a market-based support system for electricity generation from renewables which includes wind power as one of the approved techniques. The system was introduced in 2003 and aims to increase the production of electricity from renewable energy sources by 25 TWh from 2002 levels by 2020.. Wind pilot support is a support to the market for large-scale wind power. Support aims to reduce the cost of the creation of new wind energy and promoting new technologies. Wind Pilot Aid, which has existed since 2003, has been extended until in 2012 and has increased by 350 million SEK (about 36 M Euro) for the period 2008-2012. The environmental bonus, which means a tax subsidy, has been stepped down for each year until and by the year 2009, which was the last year. In 2009, environmental bonus was 0.12 SEK/kWh for electricity from offshore wind. For onshore wind power the environmentally bonus ceased in 2008

  14. Osmium in environmental samples from Northeast Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Rodushkin, Ilia [Division of Applied Geology, Lulea University of Technology, S-971 87 Lulea (Sweden); ALS Laboratory Group, ALS Analytica AB, Aurorum 10, S-977 75 Lulea (Sweden)], E-mail: ilia.rodushkin@alsglobal.com; Engstroem, Emma [Division of Applied Geology, Lulea University of Technology, S-971 87 Lulea (Sweden); Soerlin, Dieke; Ponter, Christer; Baxter, Douglas C. [ALS Laboratory Group, ALS Analytica AB, Aurorum 10, S-977 75 Lulea (Sweden)

    2007-11-01

    Osmium (Os) concentrations and {sup 187}Os/{sup 188}Os isotope abundance ratios are presented for sedimentary materials, soils, humus, plants, mushrooms, mosses and lichens collected in the vicinity of the town of Lulea, Northeast Sweden, the data for biological specimens being the first reported. Contributions from sampling and varying exposure time to the observed environmental variability were evaluated. Sedimentary materials (from both fresh and brackish water) are most elevated in radiogenic {sup 187}Os, followed by inorganic soil horizons, mushrooms and humus. The Os isotopic compositions of plants, mosses and lichens are much less radiogenic, with mean {sup 187}Os/{sup 188}Os lying within a relatively narrow 0.3-0.6 range. Significant temporal variations in Os concentrations and isotopic compositions of plant samples are attributed to integrative uptake of airborne Os with non-radiogenic composition. Measured Os concentrations in biological matrices increase in the order: small shrub leaves (blueberry and lingonberry) {<=} spruce needles {<=} mushrooms {<=} tree leaves {<=} pine needles < mosses << lichens. The concentrations found in three different species of plant were used to provide the first estimates of gaseous osmium tetroxide (OsO{sub 4}) in the environment. Though the Os content of samples from Northeast Sweden does not differ significantly from matrix-matched international reference materials (not certified for Os) of abiotic origin, the estimates of gaseous OsO{sub 4} concentrations are roughly an order of magnitude higher than have been reported for particle-bound Os in other studies. The pronounced spatial variations between relatively closely situated sites in mean {sup 187}Os/{sup 188}Os ratios for samples of the same species (presumably with the same dominating uptake mechanism) point to the presence of different local Os sources. This study therefore demonstrates that emissions of Os from automobile catalytic converters are not the only

  15. Osmium in environmental samples from Northeast Sweden

    International Nuclear Information System (INIS)

    Rodushkin, Ilia; Engstroem, Emma; Soerlin, Dieke; Ponter, Christer; Baxter, Douglas C.

    2007-01-01

    Osmium (Os) concentrations and 187 Os/ 188 Os isotope abundance ratios are presented for sedimentary materials, soils, humus, plants, mushrooms, mosses and lichens collected in the vicinity of the town of Lulea, Northeast Sweden, the data for biological specimens being the first reported. Contributions from sampling and varying exposure time to the observed environmental variability were evaluated. Sedimentary materials (from both fresh and brackish water) are most elevated in radiogenic 187 Os, followed by inorganic soil horizons, mushrooms and humus. The Os isotopic compositions of plants, mosses and lichens are much less radiogenic, with mean 187 Os/ 188 Os lying within a relatively narrow 0.3-0.6 range. Significant temporal variations in Os concentrations and isotopic compositions of plant samples are attributed to integrative uptake of airborne Os with non-radiogenic composition. Measured Os concentrations in biological matrices increase in the order: small shrub leaves (blueberry and lingonberry) ≤ spruce needles ≤ mushrooms ≤ tree leaves ≤ pine needles 4 ) in the environment. Though the Os content of samples from Northeast Sweden does not differ significantly from matrix-matched international reference materials (not certified for Os) of abiotic origin, the estimates of gaseous OsO 4 concentrations are roughly an order of magnitude higher than have been reported for particle-bound Os in other studies. The pronounced spatial variations between relatively closely situated sites in mean 187 Os/ 188 Os ratios for samples of the same species (presumably with the same dominating uptake mechanism) point to the presence of different local Os sources. This study therefore demonstrates that emissions of Os from automobile catalytic converters are not the only source of contemporary environmental contamination

  16. Mast cells in viral infections

    Directory of Open Access Journals (Sweden)

    Piotr Witczak

    2012-04-01

    Full Text Available  There are some premises suggesting that mast cells are involved in the mechanisms of anti-virus defense and in viral disease pathomechanisms. Mast cells are particularly numerous at the portals of infections and thus may have immediate and easy contact with the external environment and invading pathogens. These cells express receptors responsible for recognition of virus-derived PAMP molecules, mainly Toll-like receptors (TLR3, TLR7/8 and TLR9, but also RIG-I-like and NOD-like molecules. Furthermore, mast cells generate various mediators, cytokines and chemokines which modulate the intensity of inflammation and regulate the course of innate and adaptive anti-viral immunity. Indirect evidence for the role of mast cells in viral infections is also provided by clinical observations and results of animal studies. Currently, more and more data indicate that mast cells can be infected by some viruses (dengue virus, adenoviruses, hantaviruses, cytomegaloviruses, reoviruses, HIV-1 virus. It is also demonstrated that mast cells can release pre formed mediators as well as synthesize de novo eicosanoids in response to stimulation by viruses. Several data indicate that virus-stimulated mast cells secrete cytokines and chemokines, including interferons as well as chemokines with a key role in NK and Tc lymphocyte influx. Moreover, some information indicates that mast cell stimulation via TLR3, TLR7/8 and TLR9 can affect their adhesion to extracellular matrix proteins and chemotaxis, and influence expression of some membrane molecules. Critical analysis of current data leads to the conclusion that it is not yet possible to make definitive statements about the role of mast cells in innate and acquired defense mechanisms developing in the course of viral infection and/or pathomechanisms of viral diseases.

  17. Chronic kidney disease of uncertain etiology in Sri Lanka: Are leptospirosis and Hantaviral infection likely causes?

    Science.gov (United States)

    Gamage, Chandika Damesh; Sarathkumara, Yomani Dilukshi

    2016-06-01

    Chronic kidney disease of uncertain etiology (CKDu) has been a severe burden and a public health crisis in Sri Lanka over the past two decades. Many studies have established hypotheses to identify potential risk factors although causative agents, risk factors and etiology of this disease are still uncertain. Several studies have postulated that fungal and bacterial nephrotoxins are a possible etiological factor; however, the precise link between hypothesized risk factors and the pathogenesis of chronic kidney disease has yet to be proven in prior studies. Leptospirosis and Hantavirus infections are important zoonotic diseases that are naturally maintained and transmitted via infected rodent populations and which present similar clinical and epidemiological features. Both infections are known to be a cause of acute kidney damage that can proceed into chronic renal failure. Several studies have reported presence of both infections in Sri Lanka. Therefore, we hypothesized that pathogenic Leptospira or Hantavirus are possible causative agents of acute kidney damage which eventually progresses to chronic kidney disease in Sri Lanka. The proposed hypothesis will be evaluated by means of an observational study design. Past infection will be assessed by a cross-sectional study to detect the presence of IgG antibodies with further confirmatory testing among chronic kidney disease patients and individuals from the community in selected endemic areas compared to low prevalence areas. Identification of possible risk factors for these infections will be followed by a case-control study and causality will be further determined with a cohort study. If the current hypothesis is true, affected communities will be subjected for medical interventions related to the disease for patient management while considering supportive therapies. Furthermore and possibly enhance their preventive and control measures to improve vector control to decrease the risk of infection. Copyright © 2016

  18. The Autumn Ghost : the history of polioepidemics in Sweden

    OpenAIRE

    Axelsson, Per

    2004-01-01

    Polio epidemics appeared in Sweden in 1881 and at the turn of the 20th century the disease became an annual feature in the epidemiological pattern. Due to vaccination starting in 1957 epidemics ceased to exist in Sweden around 1965. This thesis deals with the history polio epidemics in Sweden, 1880-1965 and studies the demographical influence of polio, how the medical authorities investigated and tried to combat it, and the care of those who contracted the disease. A study of polio mortality ...

  19. Annual Report 1999. Electric power in Sweden

    International Nuclear Information System (INIS)

    2000-07-01

    Power Association is of the opinion that the increase in production taxes on nuclear power is completely misdirected. Sweden is the only EU country to have production taxes on electricity. Uncertainty and the lack of stability in the present taxation system will entail considerable difficulties both for electricity-intensive industry and for the power companies vis-a-vis long-term investment in Sweden. In 1999, overall consumption in the country fell by 0.3 TWh to 142.9 TWh, compared with last year. The decrease is explained by the fact that the autumn was very warm. Inflow into the major rivers was somewhat higher than normal enabling 70.4 TWh to be generated by the hydropower plants. This is 6 TWh more than during a normal year. Nuclear power accounted for 70.2 TWh, equal to the previous year. Additionally, combined heat and power and condensing plants accounted for 9.5 TWh, almost half of which using biofuels. Wind power continues to increase. At year-end, there were about 480 wind power plants, and the annual production was 0.4 TWh. Overall electricity production in the country was 150.5 TWh, a decrease of 3.4 TWh, or just under three percent. Exports amounted to 16.1 TWh and imports to 8.5 TWh. The average price for the year on the Nordic power exchange's spot market (Sector Sweden) was SEK 0.119 per kWh. The low price is explained by the mild weather and a plentiful supply of water in the Nordic reservoirs. On 1 November, the electricity market was changed in such a way that small consumers, with a fuse rating of up to 200 amps, were also able to take part. Parliament's decision to remove the requirement for continually registering hourly meters was of crucial importance. With this measure, the electricity market was also opened up to household customers. Hourly metering was replaced by profile settlement. Customers were offered fixed prices that could be considerably lower than previously. Flexible prices were on offer, e.g. linked to the power exchange's spot

  20. Incidence of tonsillar cancer in northern Sweden: Impact of human papilloma virus.

    Science.gov (United States)

    Loizou, Christos; Laurell, Göran; Lindquist, David; Öfverman, Charlotte; Stefansson, Kristina; Nylander, Karin; Olofsson, Katarina

    2015-12-01

    The incidence rate of tonsillar cancer is increasing worldwide. The current study identifies a parallel increase in the incidence of tonsillar cancer, human papilloma virus (HPV) and p16 expression among a population from northern Sweden, a sparsely populated area, confirming the strong association between p16 and HPV infection in tonsillar tissue. Data from the Swedish Cancer Registry was assessed to identify cases of tonsillar cancer in the northern territorial area of Sweden. HPV DNA was extracted from paraffin embedded diagnostic biopsies and detected by polymerase chain reaction using general primers Gp5+/6+ and CpI/IIG. Expression of p16 was identified by immunochemistry. Patients were grouped into urban or rural residence categories. A total of 214 cases were identified, comprising 155 (72.4%) men and 59 (27.6%) women, and 65 of these patients, who presented between 2000 and 2012, were analyzed. The overall median age for the analyzed patients was 58 years; 48 (74%) were males (median age, 57.5 years) and 17 (26%) were females (median age, 65 years). Of the 65 specimens, 59 (91%) were positive for HPV, and 62 (95%) expressed p16. The incidence of tonsillar cancer in the cohort demonstrated a 2-fold increase between 1990 and 2013; specifically, a 2.7-fold increase was observed in men whilst the female group exhibited only a small increase. These findings demonstrate a strong association between p16 expression and HPV infection in tonsillar malignancies. The incidence of HPV-positive tonsillar cancer has increased in recent years, even in sparsely populated regions, as demonstrated in northern Sweden.

  1. Hantavirus disease (nephropathia epidemica) in Belgium: effects of tree seed production and climate.

    Science.gov (United States)

    Tersago, K; Verhagen, R; Servais, A; Heyman, P; Ducoffre, G; Leirs, H

    2009-02-01

    Recently, human cases of nephropathia epidemica (NE) due to Puumala virus infection in Europe have increased. Following the hypothesis that high reservoir host abundance induces higher transmission rates to humans, explanations for this altered epidemiology must be sought in factors that cause bank vole (Myodes glareolus) abundance peaks. In Western Europe, these abundance peaks are often related to high tree seed production, which is supposedly triggered by specific weather conditions. We evaluated the relationship between tree seed production, climate and NE incidence in Belgium and show that NE epidemics are indeed preceded by abundant tree seed production. Moreover, a direct link between climate and NE incidence is found. High summer and autumn temperatures, 2 years and 1 year respectively before NE occurrence, relate to high NE incidence. This enables early forecasting of NE outbreaks. Since future climate change scenarios predict higher temperatures in Europe, we should regard Puumala virus as an increasing health threat.

  2. The U.S. Financial Crisis: Lessons From Sweden

    National Research Council Canada - National Science Library

    Jackson, James K

    2008-01-01

    In the early 1990s, Sweden faced a banking and exchange rate crisis that led it to rescue banks that had experienced large losses on their balance sheets and that threatened a collapse of the banking system...

  3. Nuclear Liability and Insurance for Nuclear Damage in Sweden

    International Nuclear Information System (INIS)

    Thofelt, H.

    1998-01-01

    This paper contains some facts about the Swedish nuclear energy production system and about the nuclear operators liability with the important issues. The nuclear insurance of Sweden is also explained in short terms. (author)

  4. Clinical application of RT-nested PCR integrated with RFLP in Hantavirus detection and genotyping: a prospective study in Shandong Province, PR China.

    Science.gov (United States)

    Liu, Yun-Xi; Zhao, Zhong-Tang; Cao, Wu-Chun; Xu, Xiao-Qun; Suo, Ji-Jiang; Xing, Yu-Bin; Jia, Ning; Du, Ming-Mei; Liu, Bo-Wei; Yao, Yuan

    2013-01-01

    The aim of the present study was to evaluate the clinical usefulness of applying RT-nested PCR along with RFLP as a method for diagnosis and genotypic differentiation of Hantavirus in the acute-stage sera of HFRS patients as compared to the ELISA technique. A prospective study of patients with suspected HFRS patients was carried out. Sera were collected for serological evaluation by ELISA and RT-nested PCR testing. Primers were selected from the published sequence of the S segment of HTNV strain 76-118 and SEOV strain SR-11, which made it possible to obtain an amplicon of 403 bp by RT-nested PCR. The genotypic differentiations of the RT-nested PCR amplicons were carried out by RFLP. Sequence analyses of the amplicons were used to confirm the accuracy of the results obtained by RFLP. Of the 48 acute-stage sera from suspected HFRS patients, 35 were ELISA-positive while 41 were positive by RT-nested PCR. With Hind III and Hinf I, RFLP profiles of the RT-nested PCR amplicons of the 41 positive sera exhibited two patterns. 33 had RFLP profiles similar to the reference strain R22, and thus belonged to the SEOV type. The other 8 samples which were collected during October-December had RFLP profiles similar to the reference strain 76-118, and thus belonged to the HTNV type. Sequence phylogenetic analysis of RT-nested PCR amplicons revealed sdp1, sdp2 YXL-2008, and sdp3 as close relatives of HTNV strain 76-118, while sdp22 and sdp37 as close relatives of SEOV strain Z37 and strain R22 located in two separate clusters in the phylogenetic tree. These results were identical to those acquired by RFLP. RT-nested PCR integrated with RFLP was a rapid, simple, accurate method for detecting and differentiating the genotypes of Hantavirus in the acute-stage sera of suspected HFRS patients. In Shandong province, the main genotypes of Hantavirus belonged to the SEOV types, while the HTNV types were observed during the autumn-winter season.

  5. Antiviral Biologic Produced in DNA Vaccine/Goose Platform Protects Hamsters Against Hantavirus Pulmonary Syndrome When Administered Post-exposure.

    Directory of Open Access Journals (Sweden)

    Nicole Haese

    Full Text Available Andes virus (ANDV and ANDV-like viruses are responsible for most hantavirus pulmonary syndrome (HPS cases in South America. Recent studies in Chile indicate that passive transfer of convalescent human plasma shows promise as a possible treatment for HPS. Unfortunately, availability of convalescent plasma from survivors of this lethal disease is very limited. We are interested in exploring the concept of using DNA vaccine technology to produce antiviral biologics, including polyclonal neutralizing antibodies for use in humans. Geese produce IgY and an alternatively spliced form, IgYΔFc, that can be purified at high concentrations from egg yolks. IgY lacks the properties of mammalian Fc that make antibodies produced in horses, sheep, and rabbits reactogenic in humans. Geese were vaccinated with an ANDV DNA vaccine encoding the virus envelope glycoproteins. All geese developed high-titer neutralizing antibodies after the second vaccination, and maintained high-levels of neutralizing antibodies as measured by a pseudovirion neutralization assay (PsVNA for over 1 year. A booster vaccination resulted in extraordinarily high levels of neutralizing antibodies (i.e., PsVNA80 titers >100,000. Analysis of IgY and IgYΔFc by epitope mapping show these antibodies to be highly reactive to specific amino acid sequences of ANDV envelope glycoproteins. We examined the protective efficacy of the goose-derived antibody in the hamster model of lethal HPS. α-ANDV immune sera, or IgY/IgYΔFc purified from eggs, were passively transferred to hamsters subcutaneously starting 5 days after an IM challenge with ANDV (25 LD50. Both immune sera, and egg-derived purified IgY/IgYΔFc, protected 8 of 8 and 7 of 8 hamsters, respectively. In contrast, all hamsters receiving IgY/IgYΔFc purified from normal geese (n=8, or no-treatment (n=8, developed lethal HPS. These findings demonstrate that the DNA vaccine/goose platform can be used to produce a candidate antiviral

  6. The Adoption of Additive Manufacturing Technology in Sweden

    OpenAIRE

    Kianian, Babak; Tavassoli, Sam; Larsson, Tobias; Diegel, Olaf

    2015-01-01

    This article analyzes the adoption of additive manufacturing (AM) technologies in Sweden. The data set consists of a recent and representative sample of Swedish AM users (companies, universities, and research institutes). The authors investigate two questions. First, what are the current applications of AM in Sweden (e.g., rapid prototyping [RP], production)? Second, what are the factors that can explain the variation in AM adoption among the users? Using a regression analysis technique, the ...

  7. Energy policies of IEA countries: Sweden - 2008 review

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-05-15

    Sweden is one of the leading IEA countries in the use of renewable energy and has a long tradition of ambitious and successful policies to improve energy efficiency. Compared to the other IEA countries, Sweden's CO2 emissions per capita and per unit of GDP are low, partly owing to efficient and low-carbon space heating, and virtually carbon-free electricity generation. The country also remains a forerunner in electricity market liberalisation. Still, even if Sweden has continued to make progress in most areas of its energy policy since the IEA last conducted an in-depth review in 2004, there is room for improvement. As Sweden plans to further increase the use of renewable energy, it is crucial that these supplies are produced and used in the most sustainable manner for the environment and the economy as a whole. With regard to CO2 emissions, more can be done in all sectors, but as transport is the largest polluter and its emissions are increasing, it is the logical focus for Sweden's efforts to reduce emissions further. This is a significant challenge. Nuclear provides almost half of the electricity in Sweden, at a low cost and without CO2 emissions. But the future of nuclear power in the national power mix is still uncertain. To provide clear guidance to the electricity sector, Sweden will need to resolve the ambiguity about the future of nuclear power in the country. This review analyses the energy challenges facing Sweden and provides critiques and recommendations for further policy improvements. It is intended to provide input to Swedish energy policy makers to help them identify a path towards a more sustainable energy future.

  8. The health and working conditions of female immigrants in Sweden

    OpenAIRE

    Akhavan, Sharareh

    2006-01-01

    Sweden is one of the European countries that has gradually changed from a mainly ethnically homogeneous society into a multi-ethnic society. This change began in the late 1940s and has increased in pace, especially since the early 1960s. The overall aim of this thesis is to understand, describe and analyze the factors that contribute to poor health among female immigrants in Sweden, from the perspectives of class, gender and ethnicity. This thesis is based on four differ...

  9. Growth & development of Indian children adopted in Sweden.

    Science.gov (United States)

    Proos, Lemm A

    2009-11-01

    More than 6800 children from India have been adopted in Sweden over the last four decades. At arrival many were undernourished and suffered from infectious diseases. Catch-up growth was common. Unexpectedly, cases of early pubertal development were subsequently reported. In order to investigate the growth and development of adopted children more in detail we studied 114 children adopted from India prospectively during two years. The majority were stunted at arrival and caught up in height and weight after two years. Psychomotor retardation and common infections diminished fairly soon. Those that were stunted did not attain the higher catch-up levels of those not stunted at arrival. Low birthweight also limited the degree of catch-up growth. 107 girls were analysed retrospectively in another study. The median menarcheal age was 11.6 yr (range 7.3-14.6 yr) which is significantly earlier than the mean in Swedish and privileged Indian girls (13.0 and 12.4-12.9 yr, respectively). The pubertal linear growth component was normal in duration and magnitude but likewise started 1.5 yr earlier. The final height/age was 154 cm (-1.4 SDS) and the weight/age 46.9 kg (-1.1 SDS) 8 per cent were 145 cm or shorter. Stunting limited catch-up growth and final height. Those that were most stunted at arrival, and had the fastest catch-up growth, had the earliest menarche. Good maternal and child nutrition is necessary for full expression of a child's growth potential. What is lost in growth early in life can only partially be recovered by catch-up growth. Such growth is associated with risk for early pubertal development which abbreviates the childhood growth period and limits final height. The mechanism underlying the early pubertal development, and the optimal management of nutrition rehabilitation after chronic malnutrition, need to be clarified by further studies.

  10. Relative Deprivation and Sickness Absence in Sweden

    Directory of Open Access Journals (Sweden)

    Jonas Helgertz

    2013-08-01

    Full Text Available Background: A high prevalence of sickness absence in many countries, at a substantial societal cost, underlines the importance to understand its determining mechanisms. This study focuses on the link between relative deprivation and the probability of sickness absence. Methods: 184,000 men and women in Sweden were followed between 1982 and 2001. The sample consists of working individuals between the ages of 19 and 65. The outcome is defined as experiencing more than 14 days of sickness absence during a year. Based on the complete Swedish population, an individual’s degree of relative deprivation is measured through income compared to individuals of the same age, sex, educational level and type. In accounting for the possibility that sickness absence and socioeconomic status are determined by common factors, discrete-time duration models were estimated, accounting for unobserved heterogeneity through random effects. Results: The results confirm that the failure to account for the dynamics of the individual’s career biases the influence from socioeconomic characteristics. Results consistently suggest a major influence from relative deprivation, with a consistently lower risk of sickness absence among the highly educated. Conclusions: Altering individual’s health behavior through education appears more efficient in reducing the reliance on sickness absence, rather than redistributive policies.

  11. Relative deprivation and sickness absence in Sweden.

    Science.gov (United States)

    Helgertz, Jonas; Hess, Wolfgang; Scott, Kirk

    2013-08-29

    A high prevalence of sickness absence in many countries, at a substantial societal cost, underlines the importance to understand its determining mechanisms. This study focuses on the link between relative deprivation and the probability of sickness absence. 184,000 men and women in Sweden were followed between 1982 and 2001. The sample consists of working individuals between the ages of 19 and 65. The outcome is defined as experiencing more than 14 days of sickness absence during a year. Based on the complete Swedish population, an individual's degree of relative deprivation is measured through income compared to individuals of the same age, sex, educational level and type. In accounting for the possibility that sickness absence and socioeconomic status are determined by common factors, discrete-time duration models were estimated, accounting for unobserved heterogeneity through random effects. The results confirm that the failure to account for the dynamics of the individual's career biases the influence from socioeconomic characteristics. Results consistently suggest a major influence from relative deprivation, with a consistently lower risk of sickness absence among the highly educated. Altering individual's health behavior through education appears more efficient in reducing the reliance on sickness absence, rather than redistributive policies.

  12. Procurement of medical equipment in Sweden

    Directory of Open Access Journals (Sweden)

    Heikki Terio

    2010-02-01

    Full Text Available In many hospitals in Sweden the importance of technology management is already accepted and accepted since the hospital managements have recognised that technology is an integral part of all major policy and planning decisions. Today’s medical devices are technically complex and sometimes a system of interacting devices is required to achieve the desired clinical function. If the hospitals want to use the latest, modern technology, then they need to make substantial investments in both equipment and competence. Complex technology, large investments and need of highly qualii ed personnel to handle the medical devices are factors that indicate a need of well-dei ned procurement process as an essential part of the total health technology management system that should be used in a hospital. In such a procurement process, carefully prepared planning of technology investments can reduce the running costs and costs for maintenance substantially. In addition, a well-dei ned procurement process contributes to increase the patient safety. In Karolinska University Hospital goods and services are purchased for more than 20% of the hospital’s €1.2 billion turnover. It is therefore very important that the procurement is carried out ef ectively.

  13. File 'Energy-climate actions in Sweden'

    International Nuclear Information System (INIS)

    2009-01-01

    In a first part, this publication briefly presents some basic data and information on Sweden (geography, population, economy, administrative organisation, powers of local authorities, local finances), the Swedish 'energy profile' (consumption, intensity, imports and exports), greenhouse gas emissions (total and per sector), and the energy-climate strategy (impacts of climate change, national climatic strategy, national measures, action framework for local authorities). The second part addresses one of these action frameworks, the Klimatkommunernas network. It describes this network, its objectives, and possibilities for communities to join it. It describes its activities: information, publication of a strategic document of climate-energy actions for municipalities, examples of projects. The third part presents experiments performed by different local communities (Kristianstad, Vaexjoe, Malmoe, and Lund). For each of them are presented: the energy strategy (objectives, strategy, adaptation, energy-climate follow-up, application and actual measures), and some specific measures. These specific examples can be integrated systems based on biogas and biomass, a zero fossil fuel objective with the use of renewable energies for heat and cold production, for electricity production and to improve energy efficiency, to promote green fuels in transports, to reduce the impact of transports on climate, a sustainable town planning, environmental management. Some features are then highlighted in the adopted approach for these examples: a systemic, collaborative, participative and communicative approach

  14. Trends in nuclear power costs in Sweden

    International Nuclear Information System (INIS)

    Vesterhaugh, O.; Blomsnes, B.

    1979-01-01

    At the request of the Swedish Ministry of Industry, a study of the costs of nuclear power in Sweden was performed early this year. The main purpose of the study was to determine the real and projected costs of electricity produced by nuclear stations. The basis for the calculations of the study was the currently planned Swedish nuclear power programme consisting of 11 reactors of which six are operating, two waiting for start-up permission and the remainder are under construction. All cost components, relevant to the commercial programme were covered, with particular emphasis on future costs for handling of spent fuel, waste disposal and plant decommissioning. A capital depreciation time of 25 years and a 4 per cent effective annual interest rate (ie interest after correction for inflation) were assumed in the calculations given in December 1978 currency. The main result of the study is the average cost per kWh for the reactors. The results are in close agreement with the cost estimate given by the Swedish Energy Commission and now that the nuclear plants produce electricity considerably cheaper than other plants with the exception of some hydroelectric ones. (author)

  15. Projects on filter testing in Sweden

    International Nuclear Information System (INIS)

    Normann, B.; Wiktorsson, C.

    1985-01-01

    The Swedish nuclear power program comprises twelve light water reactors. Nine are boiling water reactors of ASEA-ATOM design and three are pressurized water reactors of Westinghouse design. Of these, ten are in operation and two are under construction and planned to go into operation during late 1984 and early 1985, respectively. Frequent tests on the penetration of particles through HEPA filters, regular tests on the adsorption of methyl iodide in the stand-by carbon filter units by laboratory testing are discussed. The proposed new regulations are based on many years of experience of filter system operation and of tests in-situ and in the laboratory. Moisture and water are factors that affect the functioning of filters. In addition, high loading of dust can give rise to increased penetration through HEPA filters, however pinholes could have less influence on the total penetration. Laboratory tests show that DOP particles retain 30-40% in 90 mm carbon filters (8-12 mesh). However no effect on the ability of carbon to adsorb methyl iodide after DOP contamination in combined carbon/HEPA filters has been observed. Leakage from ventilation ducts can cause radioactive contamination problems during filter testing with radioiodine. In-situ testing of control-room filters has been performed using inactive methyl iodide. A type of carbon bed not previously used in Sweden has been introduced. Testing of this filter type is discussed

  16. Reindeer pastoralism in Sweden 1550-1950

    Directory of Open Access Journals (Sweden)

    Lennart Lundmark

    2007-04-01

    Full Text Available In the middle of the 16th century we get the first opportunity to a more detailed knowledge of reindeerpastoralism in Sweden. At that time the Sami lived in a hunter-gatherer economy. A family had in average about 10-20 domesticated reindeer, mainly used for transport. They could also be milked and used as decoys when hunting wild reindeer. During late 16th century the Swedish state and merchants bought large amounts of fur from the Sami. The common payment was butter and flour. This created a new prosperity, which lead to a considerable increase in population in Swedish Lapland. The population became too large for a hunter-gatherer economy. A crisis in early 17th century was the starting point for the transition to a large-scale nomadic reindeer pastoralism. Up to the middle of the 18th century intensive reindeer pastoralism was successful. But the pastoralism became gradually too intensive and diseases started to spread when the herds were kept too densely crowded for milking in summertime. During the first decades of the 19th century reindeer pastoralism in Sweden went through a major crisis. The number of reindeer herding mountain-Sami decreased considerably, mainly because they went to live permanently along the Norwegian coastline. Intensive reindeer pastoralism started to give way for extensive herding towards the end of the 19th century. In the north of Sweden influences from the Kautokeino Sami were an important factor, in the south extensive reindeer herding started to expand when the market for meat came closer to the Sami. During the 1920s the milking of reindeer ceased in Sweden, except in a few families. At that time Sami families from the north had been removed southwards. They further demonstrated the superiority of extensive herding to the Sami in mid- and southern Lapland. Reindeer pastoralism is basically a system of interaction between man and animal, but it has been heavily influenced by market forces and state intervention

  17. Occupational balance in health professionals in Sweden.

    Science.gov (United States)

    Wagman, Petra; Lindmark, Ulrika; Rolander, Bo; Wåhlin, Charlotte; Håkansson, Carita

    2017-01-01

    Health care employees are often women, a group that has high degrees of sick leave and perhaps problems attaining occupational balance. However, people think differently about their everyday activities and it is therefore important to take their perceptions into account but occupational balance has not yet been measured in health professionals. The aim was to describe occupational balance in three different samples of health professionals in Sweden. A further aim was to investigate whether occupational therapists (OTs) rate their occupational balance differently from other health professionals. Four hundred and eighty-two health professionals, employees in public dentistry, mental health care and OTs, aged 21-70 years participated. The participants' occupational balance was measured using the occupational balance questionnaire (OBQ). The ratings of occupational balance were similar to earlier studies and did not differ significantly between the samples. The OTs' occupational balance was also similar to that of the other health professionals. The similarities in occupational balance indicate the same difficulties in attaining it. The result highlights the possibility that working people face similar difficulties in achieving occupational balance. Further research is warranted about how to attain it.

  18. IAEA Team Concludes Peer Review of Sweden's Nuclear Regulatory Framework, 17 February 2012, Stockholm, Sweden

    International Nuclear Information System (INIS)

    2012-01-01

    Full text: An international team of senior nuclear safety and radiation protection experts today concluded a 12-day mission to review the regulatory framework for nuclear and radiation safety in Sweden. The Integrated Regulatory Review Service (IRRS) mission, which was conducted at the request of Sweden, noted good practices in the country's nuclear regulatory system and also made recommendations and suggestions for the Swedish Radiation Safety Authority (SSM) and the government. These are aimed at strengthening the effectiveness of the country's regulatory framework and functions in line with IAEA Safety Standards. ''Throughout the mission, the IRRS team received full cooperation from SSM staff in its review of Sweden's regulatory, technical and policy issues,'' said Georg Schwarz, mission leader and Deputy Director General of the Swiss nuclear regulator (ENSI). 'The staff were open and candid in their discussions and provided the fullest practicable assistance', he commented. The main observations of the IRRS Review team included the following: SSM operates as an independent regulator in an open and transparent manner with well-organized regulatory processes; SSM is receptive to feedback and strives to maintain a culture of continuous learning; and Following the TEPCO Fukushima Daiichi accident, SSM responded promptly to public demand for information and communicated effectively with the national government, the public and other interested parties. Good practices identified by the IRRS team included, though they are not limited to, the following: The consolidation of the two previous national regulatory authorities into SSM was successful; Overall, SSM's management system is comprehensive and contributes to staff efficiency and effectiveness; The nuclear power plant refurbishment programme as required by SSM enhanced safety; and Sweden's regulatory framework for high-level waste disposal is comprehensive and technically sound. The IRRS Review team identified

  19. Sweden in the Delaware Valley: Everyday Life and Material Culture in New Sweden

    DEFF Research Database (Denmark)

    Naum, Magdalena; Ekengren, Fredrik; Zagal Mach Wolfe, Ulla Isabel

    2013-01-01

    In 1637 the Swedish Crown, encouraged by Dutch merchants, developed a plan to establish a colonial outpost in America to tap into profitable tobacco and beaver pelt trade. The same year the first cargo ships left Sweden and sailed westwards to claim their piece of America along the Delaware River......, their perception and interactions with the neighbouring Native American groups. It discusses the ways material culture was used, exchanged and appropriated by the colonists and the local Lenape and Susquehannock in the processes of meeting, negotiations and daily coexistence....

  20. Annual Report 1999. Electric power in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-15

    . The Swedish Power Association is of the opinion that the increase in production taxes on nuclear power is completely misdirected. Sweden is the only EU country to have production taxes on electricity. Uncertainty and the lack of stability in the present taxation system will entail considerable difficulties both for electricity-intensive industry and for the power companies vis-a-vis long-term investment in Sweden. In 1999, overall consumption in the country fell by 0.3 TWh to 142.9 TWh, compared with last year. The decrease is explained by the fact that the autumn was very warm. Inflow into the major rivers was somewhat higher than normal enabling 70.4 TWh to be generated by the hydropower plants. This is 6 TWh more than during a normal year. Nuclear power accounted for 70.2 TWh, equal to the previous year. Additionally, combined heat and power and condensing plants accounted for 9.5 TWh, almost half of which using biofuels. Wind power continues to increase. At year-end, there were about 480 wind power plants, and the annual production was 0.4 TWh. Overall electricity production in the country was 150.5 TWh, a decrease of 3.4 TWh, or just under three percent. Exports amounted to 16.1 TWh and imports to 8.5 TWh. The average price for the year on the Nordic power exchange's spot market (Sector Sweden) was SEK 0.119 per kWh. The low price is explained by the mild weather and a plentiful supply of water in the Nordic reservoirs. On 1 November, the electricity market was changed in such a way that small consumers, with a fuse rating of up to 200 amps, were also able to take part. Parliament's decision to remove the requirement for continually registering hourly meters was of crucial importance. With this measure, the electricity market was also opened up to household customers. Hourly metering was replaced by profile settlement. Customers were offered fixed prices that could be considerably lower than previously. Flexible prices were on offer, e.g. linked to the

  1. Lymphogranuloma venereum rates increased and Chlamydia trachomatis genotypes changed among men who have sex with men in Sweden 2004-2016.

    Science.gov (United States)

    Isaksson, Jenny; Carlsson, Ola; Airell, Åsa; Strömdahl, Susanne; Bratt, Göran; Herrmann, Björn

    2017-11-01

    This study aimed to determine the incidence of lymphogranuloma venereum (LGV) in Sweden since 2004 and to study in detail a consecutive number of Chlamydia trachomatis cases in men who have sex with men (MSM) during a 10 month period (September 2014 to July 2015). LGV increased from sporadic import cases in 2004 to comprise a spread within Sweden in 2016. Initially, only the L2b ompA genotype was detected, but in 2015 half of the genotyped LGV cases were L2 genotype. The changing genotype distribution in Sweden is linked to increased LGV spread in Europe. High-resolution multilocus sequence typing of 168 C. trachomatis cases from MSM in 2015 resulted in 29 sequence types, of which 3 accounted for 49 % of cases. The increased rates and different genotypes of LGV indicate that more concern for high-risk taking MSM is needed to avoid further spread of this invasive infection.

  2. Population, Environmental, and Community Effects on Local Bank Vole (Myodes glareolus) Puumala Virus Infection in an Area with Low Human Incidence

    DEFF Research Database (Denmark)

    Tersago, K; Schreurs, A; Linard, C

    2008-01-01

    In this study, the distribution of Puumala hantavirus (PUUV) infection in local bank vole Myodes glareolus populations in an area with low human PUUV infection (nephropathia epidemica [NE]) incidence in northern Belgium was monitored for 2 consecutive years. Bank voles were trapped in preferred h...... activity patterns, local environmental conditions and rodent community structure are also likely to play a role in determining PUUV infection risk for humans....... habitat and tested for anti-PUUV IgG. Infection data were related to individual bank vole features, population demography, and environmental variables. Rare occurrence of PUUV infection was found and PUUV prevalence was low compared with data from the high NE incidence area in southern Belgium. Small...

  3. Income distribution and mortality in Sweden

    Directory of Open Access Journals (Sweden)

    Christina Lindholm

    2008-12-01

    Full Text Available

    Background: The hypothesis that a high income inequality on a societal level is associated with poor health outcomes has been both rejected and accepted in empirical studies. Whether the influence of economic circumstances on health operates at the individual level or societal level has important implications on policy and intervention alternatives. The objective of this study was to analyse the relationship between income inequality and mortality in Swedish municipalities and if the relationship varies depending on the mean income or on the time-lag between income inequality and mortality.

    Methods: The study was based on register data on mean income and income inequality (Gini coefficients from Statistics Sweden 1982 and 1998, aggregated on the municipality level. Data on age-standardised death rates per 100,000 persons were obtained for 1983, 1988, 1993, 1998 and 2002. The analysis on 1998 was a test of the robustness of the results.

    Results: The relationship between high income inequality in 1982 and mortality in 1983 was negative with a similar relationship in 1998. Using latency periods, the results show a decreasing trend of mortality in relation to higher Gini coefficients. A positive relationship between Gini and mean income implies that municipalities with larger income distribution also had a higher mean income and vice versa.

    Conclusions: High income inequality does not have a negative effect on mortality in Swedish municipalities. The municipalities with high income inequality have also high mean income as opposed to many other countries. The income level seems to be more substantial for mortality than the income inequality.

  4. Neotectonics in northern Sweden - geological investigations

    International Nuclear Information System (INIS)

    Lagerbaeck, R.; Witschard, F.

    1983-05-01

    Fairly large areas around the formerly known quaternary faults have been air photo interpreted. The fault known as the Parvie fault has been found to extend somewhat further towards the south, thereby crossing the valley of the Stora Lule river. Furthermore, another fault has been discovered in the Lansjaerv region, and thus the faults in this area form a better fit to the regional pattern, with a SSW - NNE trend and a relative uplift of the eastern part. The fault scarps have been leveled photogrammatrically, and reproduced on maps on the scales of 1:50000 and 1:100000, and on overview maps on the scale of 1:250000. The highest leveld scarps somewhat exceed 30 m. The total length of the faults is roughly 300 km. During the air photo interpretation, several landslides have been detected, and it seems evident from their location that there is a causal connection between faults and landslides. It seems evident that the different faults are not simultaneously formed, but created at separate events. Representative samples have been collected, and thin sections of these investigated under the microscope. Often, the bedrock shows signs of older tectonic influence, and it seems that the faults largerly have been released along existing zones of weakness in the bedrock. However, striking exceptions, with fracturing through unaltered rock, have been found in several places. The faults illustrated in the maps below undoubtedly represent the most important signs of late quaternary fault activity in Norrbotten east of the Caledonian mountains. The geographic, and very probably also causal connection between faults and landslides seems obvious in both Finland and Sweden. We need a satisfactory tectonic explanation for the faults. Undoubtedly, the glacial - isostatic forces have a central role. The strike of the faults is approximately perpendicular to the direction of plate motion, and compressive forces have acted at the formation of the faults. (author)

  5. A review of the seismotectonics of Sweden

    International Nuclear Information System (INIS)

    Muir Wood, R.

    1993-04-01

    A study has been undertaken of data relating to the seismotectonic state of Sweden, both under current conditions and also through the glaciation/deglaciation cycle. The focus of the study has been to explore primary data on all the separate sources of information bearing on seismotectonics including: a. regional tectonics, b. neotectonic surface faulting, c. geodetic and tide-gauge observations of land-level changes, d. the horizontal strain field, e. Holocene land-level changes, f. historical and instrumental seismicity, g. palaeosesmicity, h. stress determinations, and i. geothermal observations. These data have then been combined into a regional seismotectonic model, relating the distribution, style and rates of seismicity to the seismogenic properties of the crust and the continuing crustal deformation. From the evidence of the modelled and observed horizontal strain field and the diversity of focal mechanisms, all the current seismicity of the region appear to be a response to postglacial rebound. Through and understanding of the interaction between the pre-existing tectonic strain field, and the strain field resulting from glacial loading and unloading it is possible to make testable predictions about the localisation of deformation and seismicity in Fennoscandia at different stages of the glacial cycle. Immediately following glacial unloading intense deformation was concentrated on the northwestern flank of the down warped crustal bowl. Currently low-level deformation and associated seismicity is most pronounced around the western margins of the dome of postglacial rebound. While the rebound dome is primarily extensional relieving the high levels of compression that accompanied crustal down warping, there are also areas of compression and extension associated with flexures in the rebound surface that appear to affect the distribution and style of seismicity. The study shows how the significance and localisation of deformation and seismicity may be predicted

  6. Thermomechanical studies in granite at Stripa, Sweden

    International Nuclear Information System (INIS)

    Cook, N.G.W.; Myer, L.R.

    1981-01-01

    Media other than rock salt are being considered for the deep, geologic disposal of nuclear wastes. The disposal of high-level nuclear waste in a deep, underground repository will subject the rock to a thermal pulse that will induce displacements, strains, and stresses in the rock. Thermomechanical experiments, with electrical heaters simulating the thermal output of waste canisters, were carried out in granite at a depth of 340 m below surface adjacent to a defunct iron ore mine at Stripa, Sweden. Changes in temperature, displacement, and stress in the rock around these heaters were measured, and the measurements were compared with predictions calculated from the theory of linear thermoelasticity. Measured temperature changes agreed well with predictions, but measured displacements and stresses were consistently less than those predicted with constant values for the coefficient of thermal expansion and elastic properties of the rock. A laboratory test program to measure these coefficients over ranges of stress and temperature representing those in the field experiment has been initiated. Test specimens were taken from cores recovered from the instrumentation holes in the Stripa experiments. Preliminary results from laboratory tests on specimens free of joints indicate that the values of Young's modulus and Poisson's ratio increase from about 60 to 80 MPa and from 0.15 to 0.22, respectively, as the confining stress is increased from 2 to 55 MPa; these values decrease with increasing temperature, more so at 2 MPa than at 55 MPa. The linear coefficient of thermal expansion at a confining stress of 30 MPa increases from about 10 x 10 - 6 / 0 C at 40 0 C to about 14 x 10 - 6 / 0 C. The magnitudes of these changes are not sufficient to resolve the disparity between measured and predicted results. Perhaps the properties of test specimens containing joints will show greater variations in the values of the thermomechanical coefficients with temperature and pressure

  7. Insights to genetic characterization tools for epidemiological tracking of Francisella tularensis in Sweden.

    Directory of Open Access Journals (Sweden)

    Tara Wahab

    Full Text Available Tularaemia, caused by the bacterium Francisella tularensis, is endemic in Sweden and is poorly understood. The aim of this study was to evaluate the effectiveness of three different genetic typing systems to link a genetic type to the source and place of tularemia infection in Sweden. Canonical single nucleotide polymorphisms (canSNPs, MLVA including five variable number of tandem repeat loci and PmeI-PFGE were tested on 127 F. tularensis positive specimens collected from Swedish case-patients. All three typing methods identified two major genetic groups with near-perfect agreement. Higher genetic resolution was obtained with canSNP and MLVA compared to PFGE; F. tularensis samples were first assigned into ten phylogroups based on canSNPs followed by 33 unique MLVA types. Phylogroups were geographically analysed to reveal complex phylogeographic patterns in Sweden. The extensive phylogenetic diversity found within individual counties posed a challenge to linking specific genetic types with specific geographic locations. Despite this, a single phylogroup (B.22, defined by a SNP marker specific to a lone Swedish sequenced strain, did link genetic type with a likely geographic place. This result suggests that SNP markers, highly specific to a particular reference genome, may be found most frequently among samples recovered from the same location where the reference genome originated. This insight compels us to consider whole-genome sequencing (WGS as the appropriate tool for effectively linking specific genetic type to geography. Comparing the WGS of an unknown sample to WGS databases of archived Swedish strains maximizes the likelihood of revealing those rare geographically informative SNPs.

  8. Gambling in Sweden: the cultural and socio-political context.

    Science.gov (United States)

    Binde, Per

    2014-02-01

    To provide an overview, with respect to Sweden, of the cultural history of gambling, the commercialization of gambling, problem gambling research, the prevalence of problem gambling and its prevention and treatment. A review of the literature and official documents relating to gambling in Sweden; involvement in gambling research and regulation. Gambling has long been part of Swedish culture. Since about 1980 the gambling market, although still largely monopolistic, has been commercialized. At the same time, problem gambling has emerged as a concept in the public health paradigm. Debate regarding whether or not Sweden's national restrictions on the gambling market are compliant with European Community legislation has helped to put problem gambling on the political agenda. Despite expanded gambling services, the extent of problem gambling on the population level has not changed significantly over the past decade. The stability of problem gambling in Sweden at the population level suggests a homeostatic system involving the gambling market, regulation, prevention and treatment and adaption to risk and harm by gamblers. We have relatively good knowledge of the extent and characteristics of problem gambling in Sweden and of how to treat it, but little is known of how to prevent it effectively. Knowledge is needed of the effectiveness of regulatory actions and approaches, and of responsible gambling measures implemented by gambling companies. © 2013 The Author, Addiction © 2013 Society for the Study of Addiction.

  9. A database on electric vehicle use in Sweden. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Fridstrand, Niklas [Lund Univ. (Sweden). Dept. of Industrial Electrical Engineering and Automation

    2000-05-01

    The Department of Industrial Electrical Engineering and Automation (IEA) at the Lund Institute of Technology (LTH), has taken responsibility for developing and maintaining a database on electric and hybrid road vehicles in Sweden. The Swedish Transport and Communications Research Board, (KFB) initiated the development of this database. Information is collected from three major cities in Sweden: Malmoe, Gothenburg and Stockholm, as well as smaller cities such as Skellefteaa and Haernoesand in northern Sweden. This final report summarises the experience gained during the development and maintenance of the database from February 1996 to December 1999. Our aim was to construct a well-functioning database for the evaluation of electric and hybrid road vehicles in Sweden. The database contains detailed information on several years' use of electric vehicles (EVs) in Sweden (for example, 220 million driving records). Two data acquisition systems were used, one less and one more complex with respect to the number of quantities logged. Unfortunately, data collection was not complete, due to malfunctioning of the more complex system, and due to human factors for the less complex system.

  10. Evaluation of Strategies to Control a Potential Outbreak of Foot-and-Mouth Disease in Sweden

    Directory of Open Access Journals (Sweden)

    Fernanda C. Dórea

    2017-07-01

    Full Text Available To minimize the potential consequences of an introduction of foot-and-mouth disease (FMD in Europe, European Union (EU member states are required to present a contingency plan. This study used a simulation model to study potential outbreak scenarios in Sweden and evaluate the best control strategies. The model was informed by the Swedish livestock structure using herd information from cattle, pig, and small ruminant holdings in the country. The contact structure was based on animal movement data and studies investigating the movements between farms of veterinarians, service trucks, and other farm visitors. All scenarios of outbreak control included depopulation of detected herds, 3 km protection and 10 km surveillance zones, movement tracing, and 3 days national standstill. The effect of availability of surveillance resources, i.e., number of field veterinarians per day, and timeliness of enforcement of interventions, was assessed. With the estimated currently available resources, an FMD outbreak in Sweden is expected to be controlled (i.e., last infected herd detected within 3 weeks of detection in any evaluated scenario. The density of farms in the area where the epidemic started would have little impact on the time to control the outbreak, but spread in high density areas would require more surveillance resources, compared to areas of lower farm density. The use of vaccination did not result in a reduction in the expected number of infected herds. Preemptive depopulation was able to reduce the number of infected herds in extreme scenarios designed to test a combination of worst-case conditions of virus introduction and spread, but at the cost of doubling the number of herds culled. This likely resulted from a combination of the small outbreaks predicted by the spread model, and the high efficacy of the basic control measures evaluated, under the conditions of the Swedish livestock industry, and considering the assumed control

  11. Energy in Sweden. Facts and figures 2007; Energilaeget 2007

    Energy Technology Data Exchange (ETDEWEB)

    2007-12-15

    Energy in Sweden 2007: Facts and Figures contains the tabular for most of the diagrams in the main publication. These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. 2001 statistics for the period 1983-1999 where revised compared to data for previous editions. With effect from the 2001 edition, statistics are of preliminary character for the two last published years (2005 and 2006). Breakdowns into certain types of fuels vary somewhat depending on whether preliminary or final data is used. Further information about the statistics can be found in Energy in Sweden, chapter 8 Energy Facts. Please note that the figures have been rounded up or down, therefore totals do not always comply with the sum of individual figures

  12. Vocational Education and Industrial Relations: Sweden 1910–1975

    Directory of Open Access Journals (Sweden)

    Tobias Karlsson

    2018-02-01

    Full Text Available In this article we discuss vocational education in Sweden against the backdrop of the changing nature of industrial relations in the period from ca 1910 to 1975. Drawing upon evidence from official inquiries and case studies of two industries (forest industry and shipbuilding, we show that Sweden in the 1940s and 1950s can be described as a collective skill formation system in the making, where firms, intermediary associations, and the state cooperated around vocational education and training. However, Sweden developed in a very different direction than similar countries. We argue that this remarkable change of trajectory cannot be understood without considering the simultaneous disintegration of the model of industrial relations, along with general changes in the system of education.

  13. Public and political attitudes to nuclear power in Sweden

    International Nuclear Information System (INIS)

    Wikdahl, C.-E.; Swedish Atomic Forum)

    1988-01-01

    The first important decisions about a large nuclear programme in Sweden were taken in the early 1960s without any political opposition at all. The first signs of an anti-nuclear movement were seen in 1972, and at the general election in 1976 nuclear power was for the first time the main political issue. It remained so until 1980, when Parliament, after a referendum, decided to phase out nuclear power not later than the year 2010. After that decision, political interest in nuclear power evaporated, but returned again after the Chernobyl accident in April 1986. Both the decision in Parliament in 1980 and the Government's bill of May 1987 put Sweden in an unique position. Public attitudes and the political situation in Sweden are examined. (author)

  14. Quality of renewable energy utilization in transport in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Lampinen, Ari

    2015-04-01

    Renewable energy utilization in transportation (RES-T) is a long way behind its utilization in power (RES-E) and heat (RES-H) sectors. International and national environmental policies have recently given a lot of emphasis on this problem. For that reason information is sought on how to implement solutions both politically and technologically. As Sweden is a global leader in this area, it can provide valuable examples. In 2012 Sweden became the first country to reach the binding requirement of the European Union for at least 10 % share for renewable energy in transport energy consumption. But qualitative development has been even stronger than quantitative. Among the success stories behind qualitative progress, most noteworthy are those created by innovative municipal policies. By 2030 Sweden aims to achieve fossil fuel independent road transport system and by 2050 completely carbon neutral transport system in all modes of transport.

  15. An electric-drive vehicle strategy for Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Sperling, D.; Lipman, T. [California Univ., Davis, CA (United States). Inst. of Transportation Studies; Lundberg, M. [Swedish Transport and Communications Research Board, Stockholm (Sweden)

    2000-07-01

    The strategy that Sweden has taken regarding the use of electric-powered vehicles (EVs) to mitigate the environmental impacts caused by the transportation sector was discussed. Sweden's unique attributes include inexpensive and clean electricity, a strong environmental ethic and a strong automotive sector. All versions of electric-drive technology are considered to be environmentally superior to internal combustion engine vehicles. While the cost of batteries is dropping, they will remain highly priced. However, manufacturers are making larger investments into hybrid EVs and fuel cell EVs. Electric drive buses are also gaining in popularity as a means by which to reduce exhaust gases in urban areas. Sweden's industrial policy is aimed at manufacturing electrically driven heavy duty vehicles such as buses and trucks. The environmental policy is aimed at deploying small EVs for on and off-road transportation use, as well as heavy duty EVs targeted by the industrial policy. refs.

  16. Air Pollution Mortality in Denmark, Finland, and Sweden

    Directory of Open Access Journals (Sweden)

    Ulla Lehmijoki

    2009-01-01

    Full Text Available The adverse health consequences of air pollution are of concern currently and there is a fear that these consequences escalate along with economic growth. The effect of economic growth on air pollution deaths is analyzed in Denmark, Finland, and Sweden by applying the Environmental Kuznets Curve approach, according to which economic growth has competing effects on air pollution and related deaths. On the one hand, emissions tend to increase as the scale of economic activity increases, but on the other hand, consumers and firms in richer countries use cleaner goods and adopt cleaner technologies. In Denmark and Finland, the latter effects are stronger, while in Sweden the opposite is true. Therefore, air pollution deaths will decrease in Denmark and Finland but increase in Sweden. Since country's own emissions do not determine air pollution completely, the paper briefly analyzes emissions from the Baltic countries and Russia.

  17. Sweden's Leadership in a Climate Constrained World. An analysis for Sweden of the Greenhouse Development Rights framework

    Energy Technology Data Exchange (ETDEWEB)

    Kartha, Sivan; Baer, Paul; Athanasiou, Tom; Kemp-Benedict, Eric

    2008-10-15

    This report presents an analysis of the Greenhouse Development Rights framework applied to the case of Sweden. Its objective is to provide useful quantitative guidance on Sweden's role as a leader in our climate constrained world. It presents guidance that is rigorous from the standpoint of climate science and framed in the context of a right to development for the world's poor. This analysis fully accounts for Sweden's true responsibility, by looking beyond territorial emissions alone, and reckoning emissions in terms of Sweden's net 'carbon footprint.' Accounting for carbon embedded in imports, exports and international transport reveals that Sweden's responsibility is 17% larger than would be inferred by considering Sweden's territorial emissions alone. Sweden will naturally have significant obligations under any burden-sharing regime that is based on capacity and responsibility, and only more so under a regime that honors a right to development. Under the GDR framework, our indicative quantification suggests that Sweden's share of responsibility and capacity, and hence its obligation under a politically viable climate regime, will be approximately 0.51% of the global total in 2010. This can be compared to the US's 33%, the EU's 26%, Japan's 7.8%, China's 5.5%, and India's 0.5%. Sweden's 0.51% share of the global total is thus not large in absolute terms, though it is rather large relative to Sweden's small size (0.14% of the global population). These national shares shift over time, as countries' relative proportion of income and emissions change. In light of the emergence of rapidly growing developing country economies, Sweden's share of the global total obligation is projected to decline to 0.43% by 2020, and to 0.35% by 2030. This quantification of Sweden's obligation is useful in two complementary ways. First, if the total global costs of an emergency climate

  18. Potentially avoidable perinatal deaths in Denmark and Sweden 1991

    DEFF Research Database (Denmark)

    Langhoff-Roos, J; Borch-Christensen, H; Larsen, S

    1996-01-01

    to some extent could reflect differences in the quality of care, indicated by the numbers of perinatal deaths in categories of potentially avoidable deaths. MATERIAL AND METHODS: Medical records of 97% of all perinatal deaths in 1991 in the two countries were analyzed. A new classification focusing......BACKGROUND: Since 1950 the perinatal mortality has been significantly higher in Denmark than in Sweden. In 1991 the rate in Denmark was 8.0/1000 deliveries compared to 6.5/1000 in Sweden. An international audit was designed to investigate whether the perinatal death rates in the two countries...

  19. Occurrence of the hermit beetle (Osmoderma eremita), in Sweden.

    OpenAIRE

    Antonsson, Kjell; Hedin, Jonas; Jansson, Niklas; Nilsson, Sven; Ranius, Thomas

    2003-01-01

    We have compiled data on the occurrence of a threatened beetle, Osmoderma eremita, in Sweden. The species inhabits tree hollows with wood mould. The data were compiled from field surveys conducted in 1993-2003, using pitfall traps at 401 localities and using wood mould sampling at 104 localities. We have also gone through published data and all larger Swedish museums and registered old records. O. eremita was recorded at about 30% of the field surveys. In Sweden, oak is by far the most import...

  20. The bedrock and the soil types in the Finnsjoearea, Sweden

    International Nuclear Information System (INIS)

    Almen, K.-E.; Ekman, L.; Olkiewicz, A.

    1978-11-01

    This report is a part of a long-term project, started at the request of the Nuclear Fuel Safety Project, Sweden. The aim of the project is to claryfy the geohydrological situation of a drainage area close to Finnsjoen in northern Uppland, Sweden. The work comprised bedrock- and soil mapping as well as an investigation of existing literature about the geology of northern Uppland. The area is about 25 km 2 and is limited by its water-shed. The area is relatively flat, rich in outcrops - expecially in the western parts - and often swampy. Big areas of forests and agriculture have been drained by ditches. (author)

  1. Diet and Predatory Behavior of Lynx in Sweden

    DEFF Research Database (Denmark)

    Moshøj, Charlotte Margaret

    2002-01-01

    and hunters who fear predation on livestock and reindeer as well as a general reduction in wild game abundance, especially roe deer (Capreolus capreolus). Prey spectrum and predation of lynx was studied based on stomach analyses of lynx throughout Sweden and on data from a field study in south-central Sweden...... (reindeer and roe deer) comprised the greatest part of the diet, while a regional division indicated that while lynxes from northern regions had a narrower diet niche, they were in better condition than lynxes from south of the reindeer husbandry districts. Lynx gender and status also influenced diet...

  2. Potentially avoidable perinatal deaths in Denmark and Sweden 1991

    DEFF Research Database (Denmark)

    Langhoff-Roos, J; Borch-Christensen, H; Larsen, S

    1996-01-01

    BACKGROUND: Since 1950 the perinatal mortality has been significantly higher in Denmark than in Sweden. In 1991 the rate in Denmark was 8.0/1000 deliveries compared to 6.5/1000 in Sweden. An international audit was designed to investigate whether the perinatal death rates in the two countries...... to some extent could reflect differences in the quality of care, indicated by the numbers of perinatal deaths in categories of potentially avoidable deaths. MATERIAL AND METHODS: Medical records of 97% of all perinatal deaths in 1991 in the two countries were analyzed. A new classification focusing...

  3. Sustainable Development in Sweden - a success story. Discourse analysis

    International Nuclear Information System (INIS)

    Ahlberg, Malin

    2009-01-01

    In Sweden the term 'Sustainable Development' is very well known and is often used as leitmotivs in many parts of the society. Since the UN Conference on Environment and Development took place in Rio de Janeiro 1992 SD has become more and more indispensable in political debates and it has even become a crucial argument in management decisions in the business sector. Due to the tradition of consensus policy and the strong involvement of different interest group in policy decision-making processes, the idea of SD as a holistic policy concept fell in Sweden on a fruitful ground

  4. Parental leave and the glass ceiling in Sweden

    OpenAIRE

    Albrecht, James; Skogman Thoursie, Peter; Vroman, Susan

    2015-01-01

    In this paper, we update and extend "Is There a Glass Ceiling in Sweden?" (Albrecht et al. 2003) by documenting the extent to which the gender log wage gap across the distribution in Sweden has changed over the period 1998-2008. We then examine the Swedish glass ceiling in 2008 in more detail by documenting how it differs for white-collar versus blue-collar workers and for private- versus public-sector workers. We also examine when in the life cycle the glass ceiling effect arises and how thi...

  5. Energy in Sweden: Facts and figures 2009; Energilaeget 2009

    Energy Technology Data Exchange (ETDEWEB)

    2009-12-15

    Energy in Sweden 2009: Facts and figures contains the tabular for most of the diagrams in the main publication (STEM-ET--2009-30). These data consist primarily of the results of the Agency's processing of basic data from Statistics Sweden. Statistics are of preliminary character for the two last published years (2007 and 2008). Breakdowns into certain types of fuels vary somewhat depending on whether preliminary or final data is used. Please note that the figures have been rounded up or down, therefore totals do not always comply with the sum of individual figures

  6. Vaginal Infections

    Science.gov (United States)

    ... gov/ Home Body Your reproductive health Vaginal infections Vaginal infections Help for infections If you have pain, ... infections and how to prevent them. Types of vaginal infections top Two common vaginal infections are bacterial ...

  7. Infective Endocarditis

    Science.gov (United States)

    ... Center > Infective Endocarditis Menu Topics Topics FAQs Infective Endocarditis En español Infective endocarditis is an infection of ... time, congestive heart failure (CHF). What causes infective endocarditis? The infection that leads to endocarditis can be ...

  8. [TULA HANTAVIRUS IN CRIMEA].

    Science.gov (United States)

    Yashina, L N; Zaykovskaya, A V; Protopopova E K; Babkin, I V; Malyshev, B S; Tovpinets, N N; Evstafiev, I L

    2015-01-01

    Genetic evidence of the Tula virus (TULV) in Crimea region of Russia is presented. Based on the reverse transcription PCR and subsequent sequence analysis, a total of 4 RNA isolates of the TULV were identified from the tissue samples of the Altai voles Microtus obscurus captured in the Bakhchisaray district of the Republic Crimea. Phylogenetic analysis of the S-, M-, and L-segment sequences of the Crimean TULV strains showed that they formed distinct genetic lineage, Russia IV, in the TULV variant. New sequences were most closely related to the lineage Russia I sequences obtained from common vole (M. arvalis) captured in the Tula region in Central Russia

  9. Sweden-Norway at the Berlin Conference 1884-85 : History, national identity-making and Sweden's relations with Africa

    OpenAIRE

    Nilsson, David

    2013-01-01

    The international image of Sweden is one of a small, democratic and peace-loving country without the moral burden of a colonial past. This image has been reproduced in Swedish government policy as well as in most historical accounts. However, in this Current African Issues publication, the notion that “Sweden lacks a colonial past in Africa” is brought into question. The Berlin Conference 1884-85 is perhaps the most infamous political event in the history of European domination of Africa. At ...

  10. Agricultural policy and social returns to eradication programs: the case of Aujeszky's disease in Sweden.

    Science.gov (United States)

    Andersson, H; Lexmon, A; Robertsson, J A; Lundeheim, N; Wierup, M

    1997-02-01

    Economic-welfare analysis of animal disease prevention programs frequently ignore the constraints of the agricultural policy environment. Prevention programs affect producers, consumers and the government. The policy environment to a large extent determines the magnitude as well as the distribution of benefits of the program among these groups. The Swedish hog industry has been exposed to three major policy changes during the 1990-1995 period. These scenarios involve various degrees of government intervention in the agricultural sector including internal market deregulation and EU-membership. Aujeszky's disease is a virus disease with swine as the natural infection reservoir. Piglets are the most fragile and an outbreak of the disease results in symptoms such as shaking, cramps and convulsions with an increase in the mortality rate. Slaughter hogs suffer from coughing, fever and reduce their feed consumption. During the last 20-25 years the incidence of Aujeszky's disease (AD) has been increasing in Sweden. In 1989 an eradication program was undertaken. A model is developed to analyze social benefits of an eradication program given variations in agricultural policy. The model refers to the specifics of the AD-program implemented in Sweden. The expected benefits of the program are evaluated using a welfare-economic analysis applying cost-benefit analysis. Total benefits of the program are evaluated across herd and size categories and different regions. Data concerning the frequency of the virus among various categories of herds prior to enacting the program were used (Wahlström et al., 1990). In addition, data from an agricultural insurance company were used to estimate the conditional probability of an outbreak given that the herd is infected. Biological and technical parameter values were collected from a variety of sources. The results of the analysis indicate that the program is economically viable given a social rate of discount in the range of 3-5% without

  11. Forecast of icing events at a wind farm in Sweden

    DEFF Research Database (Denmark)

    Davis, Neil; Hahmann, Andrea N.; Clausen, Niels-Erik

    2014-01-01

    This paper introduces a method for identifying icing events using a physical icing model, driven by atmospheric data from the Weather Research and Forecasting (WRF) model, and applies it to a wind park in Sweden. Observed wind park icing events were identified by deviation from an idealized power...

  12. The management of intermediate level wastes in Sweden

    International Nuclear Information System (INIS)

    Hultgren, Aa.; Thegerstroem, C.

    1980-01-01

    A brief overview of current practices and research in Sweden on the management of intermediate level wastes is given. Intermediate level wastes include spent resins, filters and core components from the six power reactors in operation; radioactive wastes from nuclear fuel development at Studsvik and from non-nuclear applications are a minor contribution. (Auth.)

  13. Social Policy and Immigrant Joblessness in Britain, Germany and Sweden

    Science.gov (United States)

    Kesler, Christel

    2006-01-01

    I examine patterns of joblessness among immigrant men and women from 33 countries of origin now living in Britain, Germany and Sweden. Access to welfare, access to the labor market, job segregation and institutional support for women's employment define distinct policy configurations in these three destinations. Findings show that gaps in…

  14. At the Bridging Point: Tutoring Newly Arrived Students in Sweden

    Science.gov (United States)

    Avery, Helen

    2017-01-01

    In Sweden, tutoring in the mother tongue is a special support measure primarily intended for newly arrived students to facilitate their transition into the Swedish school system. Tutoring is premised on the collaboration between the class teacher, responsible for subject-related expertise, and the tutor, who contributes with knowledge of the…

  15. Students' Perspectives on Raising Achievement through Inclusion in Essunga, Sweden

    Science.gov (United States)

    Allan, Julie; Persson, Elisabeth

    2016-01-01

    A Swedish municipality that has transformed its position at the bottom of the national school league tables to top within three years--through inclusive education--has attracted much attention both in Sweden and internationally. This article offers the students' perspectives on the transformation and how they have experienced success. A social…

  16. Consequences of the Chernobyl accident for reindeer husbandry in Sweden

    International Nuclear Information System (INIS)

    Åhman, G.; Rydberg, A.; Åhman, B.

    1990-01-01

    Large parts of the reindeer hearding area in Sweden were contaminated with radioactive caesium from the Chernobyl fallout. During the first year after the accident no food with activity concentrations exceeding 300 Bq/kg was allowed to be sold in Sweden. This meant that about 75% of all reindeer meat produced in Sweden during the autumn and winter 1986/87 were rejected because of too high caesium activités. In May 1987 the maximum level for Cs-137 in reindeer, game and fresh-water fish was raised to 1500 Bq/kg. During the last two year, 1987/88 and 1988/89, about 25% of the slaughtered reindeer has had activities exceeding this limit. The effective long-time halflife or radiocaesium in reindeer after the nuclear weapon tests in the sixties was about 7 years. If this halflife is correct also for the Chernobyl fallout it will take about 35 years before most of the reinder in Sweden are below the current limit 1500 Bq/kg in the winter. However, by feeding the animals uncontaminated food for about two months, many reindeer can be saved for human consumption

  17. Coordination between primary and secondary healthcare in Denmark and Sweden

    Directory of Open Access Journals (Sweden)

    Sarah Wadmann

    2009-03-01

    Full Text Available Introduction: Insights into effective policy strategies for improved coordination of care is needed. In this study we describe and compare the policy strategies chosen in Denmark and Sweden, and discuss them in relation to interorganisational network theory. Policy practice: The policy initiatives to improve collaboration between primary and secondary healthcare in Denmark and Sweden include legislation and agreements aiming at clarifying areas of responsibility and defining requirements, creation of links across organisational boarders. In Denmark many initiatives have been centrally induced, while development of local solutions is more prominent in Sweden. Many Danish initiatives target the administrative level, while in Sweden initiatives are also directed at the operational level. In both countries economic incentives for collaboration are weak or lacking, and use of sanctions as a regulatory mean is limited. Discussion and conclusion: Despite a variety of policy initiatives, lacking or poorly developed structures to support implementation function as barriers for coordination. The two cases illustrate that even in two relatively coherent health systems, with regional management of both the hospital and general practice sector, there are issues to resolve in regard to administrative and operational coordination. The interorganisational network literature can provide useful tools and concepts for interpreting such issues.

  18. Consequences of the Chernobyl accident for reindeer husbandry in Sweden

    Directory of Open Access Journals (Sweden)

    Gustaf Åhman

    1990-09-01

    Full Text Available Large parts of the reindeer hearding area in Sweden were contaminated with radioactive caesium from the Chernobyl fallout. During the first year after the accident no food with activity concentrations exceeding 300 Bq/kg was allowed to be sold in Sweden. This meant that about 75% of all reindeer meat produced in Sweden during the autumn and winter 1986/87 were rejected because of too high caesium activités. In May 1987 the maximum level for Cs-137 in reindeer, game and fresh-water fish was raised to 1500 Bq/kg. During the last two year, 1987/88 and 1988/89, about 25% of the slaughtered reindeer has had activities exceeding this limit. The effective long-time halflife or radiocaesium in reindeer after the nuclear weapon tests in the sixties was about 7 years. If this halflife is correct also for the Chernobyl fallout it will take about 35 years before most of the reinder in Sweden are below the current limit 1500 Bq/kg in the winter. However, by feeding the animals uncontaminated food for about two months, many reindeer can be saved for human consumption.

  19. The Progressive Development of Environmental Education in Sweden and Denmark

    Science.gov (United States)

    Breiting, Soren; Wickenberg, Per

    2010-01-01

    Our paper traces the history and progressive development of environmental education and education for sustainable development (ESD) in Sweden and Denmark. Our main focus is on work in primary and lower secondary schools as part of a search for trends of international interest related to the conceptualisation and practice of environmental education…

  20. The Use of Personal Identity Numbers in Sweden and Denmark

    DEFF Research Database (Denmark)

    Hyltén-Cavallius, Katarina

    2015-01-01

    The paper of Katarina Hyltén-Cavallius focuses on personal identity numbers in Sweden and Denmark. This paper looks into formal and informal structures, which organise society in a host member state and which can make it difficult for a non-national Union citizen to, in practice, access public an...

  1. Is There Hidden Potential for Rural Population Growth in Sweden?

    Science.gov (United States)

    Niedomysl, Thomas; Amcoff, Jan

    2011-01-01

    Rural depopulation is a concern in many countries, and various policy initiatives have been taken to combat such trends. This article examines whether hidden potential for rural population growth can be found in Sweden. If such potential exists, it implies that the development prospects for many rural areas are not as unpromising as they may seem…

  2. Energy policies of IEA countries. Sweden 1996 review

    International Nuclear Information System (INIS)

    1996-01-01

    This IEA report provides a comprehensive, in-depth assessment of the energy policies of Sweden, including recommendations on future policy developments. Electricity is a focal point of Sweden's energy policy. After a shift in the energy mix to favour electricity in the early 1970's, nuclear and hydro power each make up about half of the electricity supply. Two key events have occurred since then: the 1980 referendum, which calls for the phase-out of all nuclear plants by 2010; the recent restructuring and liberalization of the electricity sector with the creation of a Nordic electricity market. In this context, the report argues the case for making a decision now on the nuclear issue to clarify Sweden's electricity future. Other key issues highlighted in the report include Sweden's use of economic policy instruments such as a carbon tax to achieve energy and environment goals, and the adequacy and effectiveness of government efforts to promote biofuels and energy efficiency. This report forms part of a series of periodic in-depth reviews conducted and discussed by the IEA Member countries on a four-year cycle. Short reviews of energy policy developments in all twenty-three Member countries are published annually in Energy Policies of IEA Countries. (author). 13 figs., 9 tabs., 4 appends

  3. The Role of the School Library: Reflections from Sweden

    Science.gov (United States)

    Avery, Helen

    2014-01-01

    Libraries are critical learning spaces and may play a significant role in intercultural education initiatives, particularly in Sweden where the national curriculum ascribes central functions to libraries for learning activities. Unfortunately, the ways in which teachers and librarians may collaborate to leverage mutual resources is not fully…

  4. M.S.Sigyn - Simbol of Sweden waste transport success

    International Nuclear Information System (INIS)

    Gustavson, B.; Dibek, P.

    1995-01-01

    The article is devoted to the presently existing system in Sweden of spent nuclear fuel and radioactive wastes maritime transportation from NPPs to places of permanent and intermediate storage. Transport casks and penals, their maintenance and control system are described. Explanatory work with public is partially also considered. 1 tab

  5. Comparison of the energy structures in Denmark, France and Sweden

    International Nuclear Information System (INIS)

    Nifenecker, H.

    2003-12-01

    Denmark is an example of country which involves massively in the renewable energies development and in the energy efficiency, since 1980. Facing this policy, France and Sweden produce their energy without fossil energies, mainly from nuclear and hydroelectric power. These countries energy policies, providing not much of carbon dioxide emission, are compared by the author. (A.L.B.)

  6. Life Satisfaction among Outbound Students in Northern Sweden

    Science.gov (United States)

    Nilsson, Per A.

    2015-01-01

    The transition from one's home country to a university abroad can be demanding. This study is a follow-up study exploring life satisfaction among outbound students. Outbound students at Umeå University, Sweden, were surveyed before and after experiencing studying abroad. Thus, the students' life satisfaction could be compared after an…

  7. Parental Divorce and Union Disruption among Young Adults in Sweden

    Science.gov (United States)

    Gahler, Michael; Hong, Ying; Bernhardt, Eva

    2009-01-01

    This article analyzes the impact of parental divorce on the disruption of marital and nonmarital unions among young adults in Sweden, using longitudinal data from repeated mail questionnaire surveys (1999 and 2003) with 1,321 respondents (aged 26, 30, and 34 in 2003). The study takes into account several possible mechanisms governing the…

  8. Russia’s Security Relations with Finland, Norway, and Sweden

    Science.gov (United States)

    2017-09-01

    NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release. Distribution is unlimited. RUSSIA’S SECURITY... RELATIONS WITH FINLAND, NORWAY, AND SWEDEN by Rory J. Hayden September 2017 Thesis Advisor: Mikhail Tsypkin Co-Advisor: David S. Yost...THIS PAGE INTENTIONALLY LEFT BLANK i REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public reporting burden for this collection of

  9. Privatizing Education: Free School Policy in Sweden and England

    Science.gov (United States)

    Wiborg, Susanne

    2015-01-01

    The aim of this article is to investigate why Sweden, the epitome of social democracy, has implemented education reforms leading to an extraordinary growth in Free Schools in contrast to liberal England, where Free School policy has been met with enormous resistance. Conventional wisdom would predict the contrary, but as a matter of fact Sweden…

  10. This is how we manage Sweden's radioactive waste. Activities 1995

    International Nuclear Information System (INIS)

    1996-01-01

    SKB operates systems and facilities for the management and final disposal of spent nuclear fuel and other radioactive waste in Sweden. SKB has conducted extensive R, D and D work with regard to constructing a spent fuel encapsulation plant and a deep repository in crystalline bedrock. This annual report treats all the different activities without going into technical details

  11. Biology and outbreaks of Microdiprion pallipes (Hymenoptera; Diprionidae) in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Olofsson, E. (Swedish Univ. of Agricultural Sciences, Uppsala (Sweden). Dept. of Entomology)

    1994-01-01

    During outbreaks, Microdiprion pallipes (Fall.) is the most destructive of the pine sawflies in Sweden. Its distribution includes most provinces, but damaging outbreaks have until recently occurred only in two inland areas in northern Sweden. These areas are characterised by high elevation, a harsh climate, and slow tree growth. The four recorded outbreak periods showed a 10 year periodicity. Outside these areas, a lesser outbreak occurred in 1988 to 1990, on the east coast (province of Uppland). Outbreak patterns, life history variation, and mortality factors were studied. Factors that may explain the distribution of outbreaks and the population patterns were identified.Experimental and observational evidence on the potential of various factors to influence fecundity, dispersal, and survival was evaluated. In the outbreak areas, there were few major population factors. Parasitism by Rhorus substitutor (Thunb.) was the largest cause of larval mortality and the only important density-dependent mortality factor. The different diapause strategies of M. pallipes and R. substitutor may contribute to stabilize this system. Different flight periods of the host and the parasitoid may explain a possible correlation between weather and outbreaks. Elsewhere in Sweden, where low population densities prevail, there may be similarities in population processes between M. pallipes and the other widely distributed diprionids with solitary larvae, which never have attained outbreak densities in Sweden. Interactions with other diprionids through shared natural enemies may be an important population process and may influence the distribution of outbreaks. 37 refs, 4 figs, 11 tabs

  12. The Ultimate in Flexitime: From Sweden, by Way of Volvo.

    Science.gov (United States)

    Bernstein, Paul

    1988-01-01

    In the Volvo component plant on Koping, Sweden, an innovative system of multiple shifts and flexible working hours is offered to employees. The system meets the needs of those who are available for work at certain times and helps curtail turnover and absenteeism. (JOW)

  13. Energy in Sweden. Facts and figures 1999; Energilaeget i siffror

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-11-01

    This supplement contains the tabular data of most of the diagrams in the main publication (Energy in Sweden 1999, STEM-ET-82-1999). The figures are based on preliminary statistics, and there may be minor differences between similar data in different sections or tables etc. All table headings and notes are given in both Swedish and English.

  14. The Effect of Mixed-Age Classes in Sweden

    Science.gov (United States)

    Lindstrom, Elly-Ann; Lindahl, Erica

    2011-01-01

    Mixed-aged (MA) classes are a common phenomenon around the world. In Sweden, these types of classes increased rapidly during the 1980s and 1990s, despite the fact that existing empirical support for MA classes is weak. In this paper, the effect of attending an MA class during grades 4-6 on students' cognitive skills is estimated. Using a unique…

  15. Electric power supply in Sweden 1979/80

    International Nuclear Information System (INIS)

    1981-01-01

    Generation, transmission and consumption of electricity for the year 1979/80 in Sweden are review in this report. The net supply of electricity in TWh was 60.2 from hydro, 20.1 from nuclear, 12.1 from fossil thermal and 1.4 imported. Detailed statistics are given for both consumption and generation. (L.E.)

  16. Wood production potential in poplar plantations in Sweden

    International Nuclear Information System (INIS)

    Christersson, Lars

    2010-01-01

    Shortage of oil, large variations in exports from Russia of wood to Europe, plenty of abandoned agriculture land, new ideas about a more intensive silviculture; these circumstances are driving forces in Sweden for planting fast-growing poplar and hybrid aspen clones on suitable land. The advantage of such trees is that the wood can be used for both energy (heat, biofuels, electricity), paper and for construction. Poplar clones bred in the USA and Belgium, and older hybrid aspen clones from Sweden, together with new poplar clones collected and selected for Swedish conditions from British Columbia, Canada, were planted during the 1990s in south and central Sweden. The stem diameters and heights of the trees have been measured during the last 10 years and the woody biomass production above ground has been calculated. MAI for all the plantations is 10-31 m 3 or 3-10 ton DM per hectare with the highest annual woody production of 45 m 3 or 15 ton DM per hectare in some years in a very dense plantation in the most southern part of Sweden. All the plantations have been fenced for at least the first ten years. The damage has been caused by stem canker, insects, leaf rust and by moose after removal of the fences. The possibilities for the use of poplar plantations as energy forest and vegetation filters are discussed. (author)

  17. The mites associated with Ips typographus in Sweden

    Science.gov (United States)

    John C. Moser; Hubertus H. Eidmann; Jan R. Regnander

    1989-01-01

    Twenty-four species of mites were found associated with Ips typographus (Linnaeus) collected from pherommone traps in Sweden, bringing to 38 the total recorded for this scolytid. Because three of the species are parasites, it may be possible to use them in biological control of I. typographus. Couplets from an earlier key to these...

  18. Sweden's Engagement with the Democratic People's Republic of Korea

    DEFF Research Database (Denmark)

    Andersson, Magnus; Bae, Jinsun

    2015-01-01

    on semistructured interviews of individuals who have taken part in Swedish engagement programs. Findings: - Besides having its embassy in Pyongyang and serving as a protecting power for the U.S., Sweden has provided capacity building programs for North Korean government officials and scholars and has taken part...

  19. Wood production potential in poplar plantations in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Christersson, Lars [Section of Short Rotation Forestry, VPE, SLU, Uppsala (Sweden)

    2010-09-15

    Shortage of oil, large variations in exports from Russia of wood to Europe, plenty of abandoned agriculture land, new ideas about a more intensive silviculture; these circumstances are driving forces in Sweden for planting fast-growing poplar and hybrid aspen clones on suitable land. The advantage of such trees is that the wood can be used for both energy (heat, biofuels, electricity), paper and for construction. Poplar clones bred in the USA and Belgium, and older hybrid aspen clones from Sweden, together with new poplar clones collected and selected for Swedish conditions from British Columbia, Canada, were planted during the 1990s in south and central Sweden. The stem diameters and heights of the trees have been measured during the last 10 years and the woody biomass production above ground has been calculated. MAI for all the plantations is 10-31 m{sup 3} or 3-10 ton DM per hectare with the highest annual woody production of 45 m{sup 3} or 15 ton DM per hectare in some years in a very dense plantation in the most southern part of Sweden. All the plantations have been fenced for at least the first ten years. The damage has been caused by stem canker, insects, leaf rust and by moose after removal of the fences. The possibilities for the use of poplar plantations as energy forest and vegetation filters are discussed. (author)

  20. 75 FR 57815 - Purified Carboxymethylcellulose From Finland, Mexico, Netherlands, and Sweden

    Science.gov (United States)

    2010-09-22

    ... Carboxymethylcellulose From Finland, Mexico, Netherlands, and Sweden AGENCY: United States International Trade Commission... carboxymethylcellulose from Finland, Mexico, Netherlands, and Sweden. SUMMARY: The Commission hereby gives notice of the... carboxymethylcellulose from Finland, Mexico, Netherlands, and Sweden would be likely to lead to continuation or...

  1. Licensing procedure for nuclear power in Sweden. An international look with lessons for Sweden

    International Nuclear Information System (INIS)

    Gaahlin, Emil; Nilsson, Isabelle; Pettersson, Maria; Soederholm, Patrik

    2011-02-01

    In this study we present an in-depth analysis of the existing licensing procedure for nuclear power in Sweden, and the related processes towards different public authorities. In order to put the existing legislation into context we also analyze the legal and political prerequisites for the establishment of nuclear reactors during the 1970s. The purpose of this report is thus to: (a) analyze the legal and political conditions under which the existing nuclear power plants in Sweden were built; and (b) review and analyze the existing licensing procedure for nuclear power in the country. Four main statutes (and several subordinated regulations) apply in connection with the establishment of a new nuclear plant in Sweden, including the adoption of physical plans, a principal governmental decision on the permissibility of the plant and at least five major licenses. Physical planning according to the Planning and Building Act is primarily a municipal responsibility. A plan has to meet certain environmental requirements; not least the 'provisions on efficient management of natural resources' in the Environmental Code, indicating how different kinds of land and water areas should be used and thereby direct the location of different installations. The Swedish rules are complex and vague in many respects, and may therefore imply major uncertainties for a prospective investor. The legal protection is less unclear if an area is of national interest for a specific purpose, such as nature conservation, where it normally would not be possible to locate, say, a nuclear power plant. An area may also be of national interest for nuclear plants, which of course significantly alters the preconditions in favour of the plant project. The physical planning procedure comprises an 'environmental consideration' of the plan, including an 'environmental impact assessment' (EIA), provided the plan is likely to have significant effects on the environment. This 'programmatic EIA' does however not

  2. Síndrome cardiopulmonar por hantavírus no Triângulo Mineiro e Alto Paranaíba, Minas Gerais, 1998-2005: aspectos clínico-epidemiológicos de 23 casos Hantavirus cardiopulmonary syndrome in the Triângulo Mineiro and Alto Paranaíba regions, State of Minas Gerais, 1998-2005: clinical-epidemiological aspects of 23 cases

    Directory of Open Access Journals (Sweden)

    Jean Ezequiel Limongi

    2007-06-01

    required. The present study confirmed the seasonal pattern of hantavirus cardiopulmonary syndrome in the Uberlândia region and the involvement of professional groups who are considered to be at low risk of infection, in the transmission cycle of the disease. The high lethality rate (39% and the severity of the disease observed in this study may be related to attending to these patients at a late stage.

  3. Síndrome pulmonar e cardiovascular por Hantavirus: aspectos epidemiológicos, clínicos, do diagnóstico laboratorial e do tratamento

    Directory of Open Access Journals (Sweden)

    Figueiredo Luiz Tadeu M.

    2001-01-01

    Full Text Available A síndrome pulmonar e cardiovascular por Hantavirus (SPCVH, é doença emergente com descrição crescente de casos no Brasil. Neste trabalho, estudou-se 8 casos confirmados da doença. Todos apresentaram febre e dispnéia. Taquicardia, astenia, hipotensão e estertoração pulmonar ocorreram em 75 a 87,5% dos casos. Plaquetopenia e hipoxemia ocorreram em 100% dos casos, hemoconcentração, leucocitose com desvio à esquerda e elevação de uréia e creatinina séricas em 75 a 87,5%. Assistência respiratória, hidratação endovenosa e utilização de aminas vasoativas foram as medidas utilizadas nos pacientes. Ressalta-se que o suporte ventilatório e cardiovascular deve ser precocemente instituído, preferencialmente em unidades de terapia intensiva, com precauções universais e respiratórias de isolamento. Deve-se ter cuidados com infusão excessiva de líquidos para não agravar o edema pulmonar. A mortalidade observada, de 50%, é elevada, deveu-se à gravidade da doença e ao comparecimento tardio para tratamento intensivo. Deve-se informar sobre a SPCVH aos profissionais de saúde, considerando que casos de SPCVH, provavelmente, vêm passando desapercebidos.

  4. Development of a Colloidal Gold Kit for the Diagnosis of Severe Fever with Thrombocytopenia Syndrome Virus Infection

    Directory of Open Access Journals (Sweden)

    Xianguo Wang

    2014-01-01

    Full Text Available It is critical to develop a cost-effective detection kit for rapid diagnosis and on-site detection of severe fever with thrombocytopenia syndrome virus (SFTSV infection. Here, an immunochromatographic assay (ICA to detect SFTSV infection is described. The ICA uses gold nanoparticles coated with recombinant SFTSV for the simultaneous detection of IgG and IgM antibodies to SFTSV. The ICA was developed and evaluated by using positive sera samples of SFTSV infection (n=245 collected from the CDC of China. The reference laboratory diagnosis of SFTSV infection was based on the “gold standard”. The results demonstrated that the positive coincidence rate and negative coincidence rate were determined to be 98.4% and 100% for IgM and 96.7% and 98.6% for IgG, respectively. The kit showed good selectivity for detection of SFTSV-specific IgG and IgM with no interference from positive sera samples of Japanese encephalitis virus infection, Dengue virus infection, Hantavirus infection, HIV infection, HBV surface antigen, HCV antibody, Mycobacterium tuberculosis antibody, or RF. Based on these results, the ICS test developed may be a suitable tool for rapid on-site testing for SFTSV infections.

  5. Social Pedagogy in Finland and Sweden: a comparative analysis

    Directory of Open Access Journals (Sweden)

    Juha Hämäläinen

    2015-12-01

    Full Text Available Discussing how the concept of social pedagogy has been used in Finland and Sweden, this paper provides a historical and systemic comparison of policies and practices of social pedagogy in these two countries. The main aim is to identify and explain the main similarities and differences between the Finnish and Swedish national trajectories of social pedagogical thinking and action. In the first phase of the analysis, country-specific features of social pedagogy were described paying attention to historical and structural aspects. In the second phase, these descriptions were compared in a dialogue between the au- thors, one from Finland and the other from Sweden. The dialogue-based comparison was targeted to ex- plain the identified similar and different features of social pedagogical policies and practices. The explanation was based on historical and systemic considerations, especially those of historical development, research activities, theory buildings, methodologies and techniques, professionalization and the practice fields, and the future prospects of social pedagogy.The analysis showed that the historical roots and theoretical foundations of social pedagogical think- ing and action are very similar in Finland and Sweden but the position of social pedagogy  as an academic discipline  as well as a field of practice is partly different. Since social pedagogy has not been acknowl- edged as an academic discipline in Sweden, its outlook as a field of practice is on shaky ground, while in Finland the future of social pedagogy as an academic discipline  is uncertain because the social-peda- gogical know-how based on academic education is not well known and has not found general acceptance in the field’s practice.The analysis showed that the historical roots and theoretical foundations of social pedagogical thinking and action are very similar in Finland and Sweden but the position of social pedagogy as an academic discipline as well as a

  6. Incidence of legal abortion in Sweden after the Chernobyl accident

    International Nuclear Information System (INIS)

    Odlind, V.; Ericson, A.

    1991-01-01

    The number of legal abortions in Sweden increased around the time of the Chernobyl accident, particularly in the summer and autumn of 1986. Although there was no recording of reasons for legal abortions, one might have suspected this increase to be a result of fear and anxiety after the accident. However, seen over a longer time perspective, the increase in the number of abortions started before and continued far beyond the time of the accident. There was also a simultaneous and pronounced increase in the number of births during the years subsequent to the accident. Therefore, it seems unlikely that fear of the consequences of radioactive fall-out after the Chernobyl accident resulted in any substantial increase of the number of legal abortions in Sweden

  7. Ambivalence about Children in the Family Building Process in Sweden

    Directory of Open Access Journals (Sweden)

    Bernhardt, Eva

    2014-12-01

    Full Text Available Sweden provides strong support for childbearing and parenthood, including generously subsidized medical, maternal, and child care, paid parental leave, and child allowances. In this context, attitudes towards parenthood are likely to have a particularly strong impact on the decision about whether and when to have children. We examine the links between first births and holding attitudes about children, not just of positive and negative attitudes, but also of ambivalence, namely those who both value children but also value the things that compete with parenthood for young adults’ time and other resources. Our analysis shows, measuring attitudes before the transition to parenthood, that ambivalence about childbearing delays the transition to parenthood, but not nearly as much as holding purely negative attitudes. Further, reporting an ambivalent experience from the first child had no significant effect on further childbearing, which testifies to the strong two-child norm in Sweden.

  8. A. Butovsky about the system of physical education in Sweden

    Directory of Open Access Journals (Sweden)

    Bubka S.N.

    2012-06-01

    Full Text Available The article presents an analysis of A. Butovsky's views on the physical education in Sweden, and, first of all, on the system of Swedish gymnastics. Alexey Butovsky got acquainted with it in 1892 while visiting that country on a mission trip, and later he generalized that system in some of his works. Positive and negative points of Swedish physical education, the role of the Royal Gymnastics Central Institute in Stockholm are examined, and some prominent figures of Sweden, who governed it at different periods, are characterized. Aspects of various exercises from this system are accentuated. It is marked that the Swedish gymnastics on the orientation, on principle differed composition of exercises and method of their application from other gymnastic systems in XIX century. It is underlined that exercises of the Swedish gymnastics differ naturalness of poses and motions, absence in them of maximal efforts, hard and rough motions.

  9. Reception and dissemination of American amateur telescope making in Sweden

    Science.gov (United States)

    Karnfelt, Johan

    2017-04-01

    This paper discusses the appropriation of the American Amateur Telescope Making (ATM) movement in Sweden in the 1940s and 1950s. A key player was the Swedish Astronomical Society, which in 1943, and inspired by the American example, launched a campaign to raise interest in ATM and disseminate the necessary knowledge amongst potential amateur astronomers. The campaign was successful and in just a few years it quadrupled the number of amateurs with access to telescopes. Swedish amateurs kept on building telescopes through the 1950s, but the activities then stalled with the introduction of cheap mass-market telescopes. The appropriation of ATM in Sweden is an important example of how technical innovations have shaped the course of amateur astronomy.

  10. Radioactive waste management in Sweden experiences and plans

    International Nuclear Information System (INIS)

    Wikstroem, M.

    1999-01-01

    Since some years, the necessary facilities are in operation in Sweden for the safe transport and storage of radioactive waste and spent fuel from nuclear power production. These include a final repository, SFR, for short-lived low and intermediate level waste, a central interim storage facility, CLAB, for spent fuel and a sea-based transport system. The experiences from the operation of these facilities have generally been very good. The next step is the development of an encapsulation facility and a deep repository for the spent nuclear fuel. R and D-work on direct disposal have been conducted in Sweden for more than 20 years. In the preferred method the spent fuel will be encapsulated in a copper canister with a steel internal structure, and the canister will then be disposed of at about 500 metres depth in the Swedish bedrock. The siting and design of the encapsulation facility and the deep repository is now in progress. (author)

  11. Epidemiology and Ecology of Tularemia in Sweden, 1984–2012

    Science.gov (United States)

    Desvars, Amélie; Furberg, Maria; Hjertqvist, Marika; Vidman, Linda; Sjöstedt, Anders; Rydén, Patrik

    2015-01-01

    The zoonotic disease tularemia is endemic in large areas of the Northern Hemisphere, but research is lacking on patterns of spatial distribution and connections with ecologic factors. To describe the spatial epidemiology of and identify ecologic risk factors for tularemia incidence in Sweden, we analyzed surveillance data collected over 29 years (1984–2012). A total of 4,830 cases were notified, of which 3,524 met all study inclusion criteria. From the first to the second half of the study period, mean incidence increased 10-fold, from 0.26/100,000 persons during 1984–1998 to 2.47/100,000 persons during 1999–2012 (ptularemia was higher than expected in the boreal and alpine ecologic regions (ptularemia in Sweden and illustrate that incidence is higher in locations near lakes and rivers. PMID:25529978

  12. Guide tube support pin experience at Ringhals plant, Sweden

    International Nuclear Information System (INIS)

    Ericsson, E.

    1984-01-01

    The intention with my presentation is to give an information about how we finally made the decision to make the replacement of Guide Tube Support Pin (GTSP) on unit 3 and how it was done. At the Ringhals Plant in Sweden, there are four units of which three are Westinghouse 3-loop PWR:s. One unit is an ASEA-ATOM BWR. Mainly due to climate reasons with a long and cold winter and switching to electrical heating in Swedish housing, a demand for highest possible availability of electrical power supply during the winter season has become a necessity. Therefore all refueling/maintenance outages for the nuclear units in Sweden are scheduled during the summer months, when also all recognized risks for disturbances during the following operation period have to be eliminated

  13. The MTO concept and organisational learning at Forsmark NPP, Sweden

    International Nuclear Information System (INIS)

    Andersson, Olle; Rollenhagen, Carl

    2002-01-01

    The term 'MTO' (Man-Technology-Organisation) has been widely used by Swedish utilities and regulators to describe knowledge and analytical techniques that focus on human and organisational factors and their relationship with nuclear safety. MTO was introduced in Sweden after the TMI accident as a concept similar to the 'Human Factors' (HF) concept developed in the USA. It was the intent that the explicit mention of the three interrelated elements in the concept - Man, Technology and Organisation - would stimulate a comprehensive 'system view' on nuclear safety. This view should go beyond a strict technological perspective to recognise and highlight human and organisational factors as important moderators of risk. In retrospect, the MTO concept has been successful in stimulating a socio-technological view of nuclear safety in Sweden - a general trend supported by international developments. A further step along this path has been taken with the LearnSafe project. (author)

  14. International Uranium Resources Evaluation Project (IUREP) national favourability studies: Sweden

    International Nuclear Information System (INIS)

    1977-11-01

    Sweden, covers an area of approx. 450 000 square kilometers. It has a population of 8 millions. With few exceptions in the northern part the access can be regarded as good. A dense network of motorroads and railroad exists. The results obtained by the exploration works combined with other available geo-information permit a separation of two principal uranium provinces in Sweden. The first one is confined to sediments of Upper Cambrian and Lower Ordovician which appears in Southern Sweden and along the border of the Caledonian mountain range in Central Sweden. The uranium occurrence are stratiform, of blackshale type which occurs in the Peltura zone of Upper Cambrian or they are associated to a phosphatite-bearing unit of Lower Ordovician overlying the Cambrian shale formation. The distribution of uranium in Upper Cambrian rocks is in general dependant on their lithology which itself is related to the paleography. This conditions explain relatively higher uranium content of the shale from Billigen.The potential resources of the province are estimated at about 1 million tonnes uranium. The second uranium province, called Arjeplog-Arvidsjaur, situated immediately south of the Arctic circle, comprises one deposit - Pleutajokk - and a group of more than twenty occurrences of similar characteristics and age (1 700 - 1 800 my.). The results of the past exploration have shown that uranium is present in different types of rocks. Because of the presence of uranium in many of the pegmatites the possibility of the formation of large low grade deposits should be tested. Favourable areas are those regions where the geological conditions are similar to the geology of the Grenville province in Canada or the Damara belt of SW-Africa. Special studies are recommended on this subject

  15. Power and Authority. Birgitta of Sweden and her Revelations

    OpenAIRE

    Salmesvuori, Päivi

    2009-01-01

    In the High Middle Ages female saints were customarily noble virgins. Thus, as a wife and a mother of eight children, the Swedish noble lady Birgitta (1302/3 1373) was an atypical candidate for sanctity. However, in 1391 she was canonized only 18 years after her death and became a role model for many late medieval women, who were mothers and widows. The dissertation Power and Authority Birgitta of Sweden and Her Revelations investigates how Birgitta went about establishing her power an...

  16. Japanese Mobile Phone Usage in Sweden - Technological and Social Prerequisites

    OpenAIRE

    Fredriksson, Susanne; Hillerdal, Ida

    2010-01-01

    Japan is an advanced country when it comes to mobile phone technology. This thesis firstly investigates the mobile phone usage in Japan. Secondly it describes the prerequisites for implementation of some distinguished Japanese mobile phone functions in Sweden. This is done from a social as well as a technological aspect. The Japanese mobile phone usage is investigated on three levels; governmental, industrial and consumer. The governmental level is characterised by an ICT policy which strives...

  17. The Rise of the Nuclear System of Innovation in Sweden

    International Nuclear Information System (INIS)

    Jonter, Thomas; Fjaestad, Maja

    2008-04-01

    The purpose of this article is twofold. Firstly, the ambition is to analyze the role of the government in relation to private industry in the development of the nuclear power infrastructure in Sweden in the period of 1945-1970. Secondly, the purpose is to account for what was actually made in terms of education, research and financial funding in 'the Swedish line' and to assess its importance for the swift take over by the light water reactor system

  18. Training and accreditation for radon professionals in Sweden

    International Nuclear Information System (INIS)

    Mjoenes, L.; Soederman, A.-L.

    2004-01-01

    Radon training courses and seminars on radon have been arranged in Sweden since the early 1980s. A commercial educational company initiated the first regular training courses in 1987. Up to 1990 about 400 persons had attended courses in radon measurement and radon mitigation methods. In 1991 the training programme was taken over by the Swedish Radiation Protection Authority, SSI. Today SSI's Radon Training Programme comprises three different two-day courses, a Basic Radon Course and two continuation courses: Radon Measurements and Radon in Water. Until 2003 SSI also arranged courses about Radon Remedial Measures and Radon Investigation and Risk Map Production. The courses are arranged twice a year. Altogether, about 750 municipal environmental health officers and technicians from private companies have been educated in the SSI training programme between 1991 and 2003. The continuation courses are completed with an examination, consisting of a theoretical test. The names of the persons who pass are being published in a list that is found on the SSI web site. Since no certification system is currently in place for radon professionals in Sweden, this list helps people who need to get in contact with radon counsellors to find one in their area and is used by authorities as well as private house-owners. Since 1991 it has been possible to obtain accreditation for measurements of indoor radon in Sweden and since 1997, also for measurements of radon in water. Although accreditation is voluntary in Sweden, accredited laboratories perform most measurements, both for indoor air and water. Passing the examination in the SSI training courses is a condition for accreditation. The Swedish Board for Accreditation and Conformity Assessment, SWEDAC, is in charge of the accreditation. So far, three major companies have obtained accreditation for measurement of indoor radon and four have been accredited for measurements of radon in water

  19. The sensitivity of snowfall to weather states over Sweden

    Science.gov (United States)

    Norin, Lars; Devasthale, Abhay; L'Ecuyer, Tristan S.

    2017-09-01

    For a high-latitude country like Sweden snowfall is an important contributor to the regional water cycle. Furthermore, snowfall impacts surface properties, affects atmospheric thermodynamics, has implications for traffic and logistics management, disaster preparedness, and also impacts climate through changes in surface albedo and turbulent heat fluxes. For Sweden it has been shown that large-scale atmospheric circulation patterns, or weather states, are important for precipitation variability. Although the link between atmospheric circulation patterns and precipitation has been investigated for rainfall there are no studies focused on the sensitivity of snowfall to weather states over Sweden.In this work we investigate the response of snowfall to eight selected weather states. These weather states consist of four dominant wind directions together with cyclonic and anticyclonic circulation patterns and enhanced positive and negative phases of the North Atlantic Oscillation. The presented analysis is based on multiple data sources, such as ground-based radar measurements, satellite observations, spatially interpolated in situ observations, and reanalysis data. The data from these sources converge to underline the sensitivity of falling snow over Sweden to the different weather states.In this paper we examine both average snowfall intensities and snowfall accumulations associated with the different weather states. It is shown that, even though the heaviest snowfall intensities occur during conditions with winds from the south-west, the largest contribution to snowfall accumulation arrives with winds from the south-east. Large differences in snowfall due to variations in the North Atlantic Oscillation are shown as well as a strong effect of cyclonic and anticyclonic circulation patterns. Satellite observations are used to reveal the vertical structures of snowfall during the different weather states.

  20. Majority versus Minority: ‘Governmentality’ and Muslims in Sweden

    Directory of Open Access Journals (Sweden)

    Anne Sofie Roald

    2013-02-01

    Full Text Available This article deals with the Muslim community in Sweden in view of the majority–minority dynamics with focus on how values, attitudes, behaviors, and practices of the Swedish majority influence Muslim minority communities and how majority society’s approach to Muslims and Islam influences both the relationship Muslims have with non-Muslims and the understandings that Muslims have of Islam.

  1. Preliminary study of the heating market in Sweden

    International Nuclear Information System (INIS)

    1999-01-01

    The successive deregulation of the market for electric power, in Sweden as well as abroad, results in an increased competition in generation and trade of electricity. This market that previously was known for its oligopoly in the production sector and its monopoly in the distribution sector has now been opened for competition. This study is focused on the district heating sector, because it is still comparatively unregulated, and because it partly comprises what is called natural monopolies

  2. Establishment and early management of Populus species in southern Sweden

    OpenAIRE

    Mc Carthy, Rebecka

    2016-01-01

    Populus species are among the most productive tree species in Sweden. Interest in growing them has increased during the 21st century due to political goals to increase the share of renewable energy and to increase the proportion of hardwood species in forests. Populus species have been shown to be potentially profitable, but currently they are mostly planted on abandoned agricultural land. There is a lack of knowledge about the establishment of Populus species on forest sites. There is also a...

  3. Female labour force participation, fertility and public policy in Sweden.

    Science.gov (United States)

    Sundstrom, M; Stafford, F P

    1992-01-01

    2nd only to Ireland in total fertility, Sweden has the highest total fertility (TFR) and female labor force participation rates (FLFPR) among European countries in the late 1980s and early 1990s. 1988 TFR and FLFPR were 1.96 and 80.1%, respectively. This paper considers the role of public policy in creating this unique trend, with particular focus on family leave policy. In 1974, Sweden became the 1st country to allow leave to both parents following childbirth. By 1990, leave duration had grown from an initial 6-month period to 15 months. In addition, subsidized day care, flexible working hours, and economic support to families with children is provided in the context of a family-supportive tax structure. While generous, benefits are related to work and income history. Labor income is replaced at 90% of gross earnings, while the unemployed receive only minimal taxable flat payments. Benefits overall are paid from general taxes. Given that benefits reflect job history and income, and income level tends to rise fastest in the initial stages of employment, women in Sweden postpone childbirth in order to realize wage increases and greater job standing over the short- to medium-terms. In sum, Sweden's policies stimulate both fertility and women's paid work by reducing the costs of having children while requiring parents to be employed to receive full benefits. This paper further reviews the development of parental leave and related policies and compares Swedish fertility, female labor force participation, and parental leave benefits to those of countries in the European Community.

  4. Impact of energy-saving information in Sweden. [Monograph

    Energy Technology Data Exchange (ETDEWEB)

    Byman, D; Furubo, J E

    1980-02-01

    Energy conservation is a central part of Sweden's national energy policy. It represents an important means of attaining the goals that have been set for this policy: (1) safeguarding sources of supply; (2) curbing energy-transformation effects and reinforcing safety measures; and (3) freedom of action and flexibility. Government measures, public-information activities, and the help of many organizations in accomplishing the goals are emphasized here.

  5. A profile and analysis of willow growers in Sweden

    International Nuclear Information System (INIS)

    Rosenqvist, H.; Roos, A.; Ling, E.; Hektor, B.

    1999-01-01

    Willow plantations on Swedish farmland increased considerably between 1991 and 1996. The main driving forces behind this development were (1) the 1991 introduction of an agriculture deregulation policy in Sweden which created lower grain prices and simultaneously introduced compensation for set-aside land and subsidies for willow plantations on surplus arable land, (2) higher taxes on fossil fuels, and (3) the existence of a biofuel market in Sweden based on forest fuels. This paper presents a statistical study of 1,158 willow growers in southern and central-eastern Sweden. The resulting profile of growers will help policy makers and agents in the bioenergy business design information campaigns and marketing strategies. Willow growers are described according to geographical distribution, willow parcel sizes, farm sizes, and farm types. They are compared with the population of farmers who are not growing willow. Willow growers are more often between 50-65 years of age, and they have larger farms than non-willow growers. They are less often focused on animal and milk production and more often on cereal and food crop production than are other farmers. (author)

  6. Epidemiology of Chronic Pain in Denmark and Sweden

    Directory of Open Access Journals (Sweden)

    Julie Harker

    2012-01-01

    Full Text Available Introduction. Estimates on the epidemiology of chronic pain vary widely throughout Europe. It is unclear whether this variation reflects true differences between populations or methodological factors. Information on the epidemiology of chronic pain can support decision makers in allocating adequate health care resources. Methods. In order to obtain epidemiological data on chronic pain in Denmark and Sweden, we conducted a literature review of epidemiological data primarily on chronic noncancer pain, prioritising studies of highest quality, recency, and validity by conducting a systematic search for relevant studies. Following quality assessment, data were summarised and assigned to the research questions. Results. The prevalence of moderate to severe noncancer pain was estimated at 16% in Denmark and 18% in Sweden. Chronic pain impacts negatively on perceived health status, quality of life and is associated with increased cost. Despite using pain medications, a large proportion of chronic pain sufferers have inadequate pain control. There was a lack of high-quality and low-bias studies with clear inclusion criteria. Conclusions. In both Denmark and Sweden, chronic pain is a common health problem which is potentially undertreated and warrants attention of health care workers, policy makers and researchers. Future research should utilise clear reporting guidelines to assist decision and policy makers, in this important area.

  7. Long term health effects in Sweden from the Chernobyl accident

    Energy Technology Data Exchange (ETDEWEB)

    Falk, R; Mellander, H; Moberg, L; Edvardson, K; Nyblom, L [Swedish Radiation Protection Inst., Stockholm (Sweden)

    1997-09-01

    The morning of 28 April 1986 was the beginning of an intensive period of radiation protection work in Sweden. During that morning the Chernobyl accident became known in the western world through the detection of radioactive contamination in Sweden and at the Forsmark nuclear power plant in particular. The environmental consequences of the fallout have been studied in various research projects. The effects on agriculture in Sweden was mainly limited to the first year after the accident. The long term effects are instead seen in products from the semi-natural ecosystems: in moose, roedeer, reindeer, mushrooms and fish from lakes in areas with a high deposition of radioactive caesium. High concentrations of {sup 137}Cs in reindeer meat in combination with an estimated effective ecological half-life of about 4 years, will cause problems for reindeer husbandry in the most contaminated parts for many years to come. In moose, roedeer and mushrooms, the ecological half-lives are very long and in some compartments seem to approach the physical half-life of {sup 137}Cs. 22 refs, 3 figs.

  8. Long term health effects in Sweden from the Chernobyl accident

    International Nuclear Information System (INIS)

    Falk, R.; Mellander, H.; Moberg, L.; Edvardson, K.; Nyblom, L.

    1997-01-01

    The morning of 28 April 1986 was the beginning of an intensive period of radiation protection work in Sweden. During that morning the Chernobyl accident became known in the western world through the detection of radioactive contamination in Sweden and at the Forsmark nuclear power plant in particular. The environmental consequences of the fallout have been studied in various research projects. The effects on agriculture in Sweden was mainly limited to the first year after the accident. The long term effects are instead seen in products from the semi-natural ecosystems: in moose, roedeer, reindeer, mushrooms and fish from lakes in areas with a high deposition of radioactive caesium. High concentrations of 137 Cs in reindeer meat in combination with an estimated effective ecological half-life of about 4 years, will cause problems for reindeer husbandry in the most contaminated parts for many years to come. In moose, roedeer and mushrooms, the ecological half-lives are very long and in some compartments seem to approach the physical half-life of 137 Cs. 22 refs, 3 figs

  9. The sacred foodscapes of Thai Buddhist temples in Sweden

    Directory of Open Access Journals (Sweden)

    Katarina Plank

    2015-01-01

    Full Text Available Thai Buddhist communities are by far the fastest-growing Buddhist establishments in Sweden, and – contrary to other Buddhist congregations that are mainly clustered in the cities – Thai Buddhist temples can be found in sparsely-populated areas and rural parts of Sweden. This article aims to document and analyse the ‘foodscape’ of diasporic Thai Buddhism in Sweden. In particular the article identifies and discusses five different strategies used by local communities- in order to support their temples in urban as well as rural areas: 1 local support, 2 pre-cooking and freezing, 3 pre-organised almsgiving in nearby cities, 4 change of food gifts, 5 change of the nikaya. A temple’s location in a rural area can drive forward a reinterpretation and adaptation of the monk’s rules, and contribute to a changing composition of food gifts. Food performs several functions. In addition to the religious functions that are associated with almsgiving, food can also serve as a means of generating bonding and bridging civic social capital, and providing economic income to temples.

  10. Assessment of soil acidification effects on forest growth in Sweden

    International Nuclear Information System (INIS)

    Sverdrup, H.; Warfvinge, P.; Nihlgaard, B.

    1994-01-01

    The results of mapping critical loads, areas where they have been exceeded and steady state (Ca+Mg+K)/Al ratios of soils in Sweden, has been used to assess the order of magnitude of the ecological and economic risks involved with acid deposition for Swedish forests. The results of the calculations indicate that 81% of the Swedish forested area received acid deposition in excess of the critical load at present. Under continued deposition at 1990 level, forest die-back is predicted to occur on approximately 1% of the forested area, and significant growth rate reductions are predicted for 80% of the Swedish forested area. For Sweden, growth losses in the order of 17.5 million m -3 yr -1 are predicted, equivalent to approximately 19% of current growth. Comparable losses can be predicted for other Nordic countries. The soil acidification situation is predicted to deteriorate significantly during the next 5-15 years, unless rapid emission reductions can be achieved. A minimum deposition reduction over Sweden of 95% on sulphur deposition and 30% on the N deposition in relation to 1990 level is required in order to protect 95% of the Swedish forest ecosystems from adverse effects of acidification. A minimum reduction of 60% on sulphur deposition and 30% on the N deposition is required to keep forest harvest at planned levels. 148 refs., 9 figs., 9 tabs

  11. Identification of potential opinion leaders in child health promotion in Sweden using network analysis.

    Science.gov (United States)

    Guldbrandsson, Karin; Nordvik, Monica K; Bremberg, Sven

    2012-08-08

    Opinion leaders are often local individuals with high credibility who can influence other people. Robust effects using opinion leaders in diffusing innovations have been shown in several randomized controlled trials, for example regarding sexually transmitted infections (STI), human immunodeficiency virus (HIV) prevention, mammography rates and caesarean birth delivery rates. In a Cochrane review 2010 it was concluded that the use of opinion leaders can successfully promote evidence-based practice. Thus, using opinion leaders within the public health sector might be one means to speed up the dissemination of health promoting and disease preventing innovations. Social network analysis has been used to trace and map networks, with focus on relationships and positions, in widely spread arenas and topics. The purpose of this study was to use social network analysis in order to identify potential opinion leaders at the arena of child health promotion in Sweden. By using snowball technique a short e-mail question was spread in up to five links, starting from seven initially invited persons. This inquiry resulted in a network consisting of 153 individuals. The most often mentioned actors were researchers, public health officials and paediatricians, or a combination of these professions. Four single individuals were mentioned by five to seven other persons in the network. These individuals obviously possess qualities that make other professionals within the public health sector listen to and trust them. Social network analysis seemed to be a useful method to identify influential persons with high credibility, i.e. potential opinion leaders, at the arena of child health promotion in Sweden. If genuine opinion leaders could be identified directed measures can be carried out in order to spread new and relevant knowledge. This may facilitate for public health actors at the local, regional and national level to more rapidly progress innovations into everyday practice. However

  12. Awareness of risk factors for cancer: a comparative study of Sweden and Denmark.

    Science.gov (United States)

    Lagerlund, Magdalena; Hvidberg, Line; Hajdarevic, Senada; Fischer Pedersen, Anette; Runesdotter, Sara; Vedsted, Peter; Tishelman, Carol

    2015-11-23

    Sweden and Denmark are neighbouring countries with similarities in culture, healthcare, and economics, yet notable differences in cancer statistics. A crucial component of primary prevention is high awareness of risk factors in the general public. We aimed to determine and compare awareness of risk factors for cancer between a Danish and a Swedish population sample, and to examine whether there are differences in awareness across age groups. Data derive from Module 2 of the International Cancer Benchmarking Partnership. Telephone interviews were conducted with 3000 adults in Denmark and 3070 in Sweden using the Awareness and Beliefs about Cancer measure. Data reported here relate to awareness of 13 prompted risk factors for cancer. Prevalence ratios with 95 % confidence intervals were calculated to examine associations between country, age, and awareness of risk factors. Over 90 % of respondents in both countries recognized smoking, use of sunbeds and ionizing radiation as risk factors for cancer. Lowest awareness (awareness than Danish respondents for ten of the 13 risk factors studied. Respondents from Denmark reported higher awareness only regarding low fruit and vegetable intake and use of sunbeds. Low physical activity was the only risk factor for which there was no difference in awareness between the countries. A decline in awareness was generally seen with increasing age in both countries, but deviating patterns were seen for alcohol intake, red/processed meat, obesity and age 70+. This study supports findings from other European studies that generally demonstrate modest public awareness of many established cancer risk factors. Efforts should be made to improve awareness of the cancer risk factors HPV-infection, low fruit and vegetable intake and alcohol intake, which showed particularly low awareness in both countries. Previous studies indicate that repeated, broad campaigns are successful, and suggest that a multimedia approach is used.

  13. Policy instruments for development of wind power in Sweden

    International Nuclear Information System (INIS)

    Aastrand, Kerstin; Neij, Lena

    2003-01-01

    It is often believed that energy policy and policy instruments can play a significant role in the transition towards sustainable energy by stimulating and accelerating the development and deployment of new energy technologies. However, despite the known need for, and benefits of, new energy technologies their market introduction and expansion is often slow. Wind power has been on the political agenda since the 1970s in several European countries as well as in other countries throughout the world. However, the technology and market development of wind power has been very different in these countries. Despite three decades of policy intervention the installed capacity in Sweden was only 265 MW in 2000, compared with 6,107 MW in Germany, 2,836 MW in Spain and 2,341 MW in Denmark. This report analyses the effects of policy instruments on wind power development in Sweden and identifies possible reasons why wind power has not been installed to a greater extent. The analysis is based on an empirical example of a socio technological system-based approach to evaluation of technology and market development for new energy technologies; i.e. an approach focused on the technological system including the actors, institutions and organizations that build, drive and utilise it and the economic and legal framework that regulates it. The aim is to assess the impact on technology and market development and to discuss the relatively late and slow wind power development in Sweden. The report also examines the achievement of governmental energy policy goals. Using the socio-technological systems approach we analyse Swedish policy programmes and wind power development between 1975 and 2000. The political and economic framework is identified. The discussion of the political and economic frameworks is limited to public policy goals and policy instruments. The policy focus is set to policy instruments aimed for technology and market development of wind power, such as research and

  14. Cohort Profile: the National Prostate Cancer Register of Sweden and Prostate Cancer data Base Sweden 2.0.

    Science.gov (United States)

    Van Hemelrijck, Mieke; Wigertz, Annette; Sandin, Fredrik; Garmo, Hans; Hellström, Karin; Fransson, Per; Widmark, Anders; Lambe, Mats; Adolfsson, Jan; Varenhorst, Eberhard; Johansson, Jan-Erik; Stattin, Pär

    2013-08-01

    In 1987, the first Regional Prostate Cancer Register was set up in the South-East health-care region of Sweden. Other health-care regions joined and since 1998 virtually all prostate cancer (PCa) cases are registered in the National Prostate Cancer Register (NPCR) of Sweden to provide data for quality assurance, bench marking and clinical research. NPCR includes data on tumour stage, Gleason score, serum level of prostate-specific antigen (PSA) and primary treatment. In 2008, the NPCR was linked to a number of other population-based registers by use of the personal identity number. This database named Prostate Cancer data Base Sweden (PCBaSe) has now been extended with more cases, longer follow-up and a selection of two control series of men free of PCa at the time of sampling, as well as information on brothers of men diagnosed with PCa, resulting in PCBaSe 2.0. This extension allows for studies with case-control, cohort or longitudinal case-only design on aetiological factors, pharmaceutical prescriptions and assessment of long-term outcomes. The NPCR covers >96% of all incident PCa cases registered by the Swedish Cancer Register, which has an underreporting of <3.7%. The NPCR is used to assess trends in incidence, treatment and outcome of men with PCa. Since the national registers linked to PCBaSe are complete, studies from PCBaSe 2.0 are truly population based.

  15. Oil and Gas Emergency Policy: Sweden 2012 update

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    Oil and natural gas represented respectively 27% and 3% of Sweden’s total primary energy supply (TPES) in 2010. With coal representing 5% of TPES, Sweden has the lowest share of fossil fuels in the energy supply mix among IEA member countries. This is a significant difference from the mid-1970s, when fossil fuels made up three-quarters of Sweden’s energy supply, and is the result of a concerted effort to move away from the use of oil through the development of nuclear and renewable energy sources. Sweden’s energy policy seeks to further increase the share of renewable energy sources, including having them provide half of all energy, and 10% of all transport needs, by 2020. The share of fossil fuel is also to be further reduced, through plans to fully eliminate their use for heating purposes by 2020 and having a vehicle stock in Sweden that is ''independent'' of fossil fuels by 2030. Under this policy, demand for both oil and natural gas is anticipated to decline from current levels. Oil demand in Sweden was nearly 330 thousand barrels per day (kb/d) in 2011. While fully dependent on imports to meet domestic oil demand, Sweden is a net exporter of refined oil products. Overall oil demand will likely decline in the coming decade, however demand for oil in the transport sector is expected to grow. At the same time, oil demand will be ever more concentrated on transport diesel, with demand for the fuel reaching over 110 kb/d by 2020 compared to just under 80 kb/d in 2011. Concerning natural gas, consumption in Sweden totalled 1.3 billion cubic metres (bcm) in 2011, all of which was supplied via a single interconnector with Denmark. While natural gas plays only a minor role in Sweden’s TPES, its role in the energy supply of southern and western Sweden is much more substantial, accounting for around 20% of the area’s total energy use. Around 30 large consumers, including CHP plants, account for roughly 80% of total gas demand in the country

  16. Biology and distribution of chafers (Coleoptera, Scarabaeidae) living in hollow trees in Sweden.

    OpenAIRE

    Nilsson, Sven; Baranowski, Rickard; Hedin, Jonas; Jansson, Niklas; Ranius, Thomas

    2002-01-01

    We review the ecology and distributions of the chafers Liocola marmorata (F.), Gnorimus nobilis (L.) and Gnorimus variabilis (L.) in Sweden based on museum and several large private collections. These species live in hollow deciduous trees, in Sweden especially in oaks. The former and recently documented localities are shown on maps. More than 100 years ago, all the species as well as their habitats were more common in Sweden than today. One problem when interpreting old finds is that hollow ...

  17. 76 FR 27663 - Purified Carboxymethylcellulose From Finland, Mexico, Netherlands and Sweden

    Science.gov (United States)

    2011-05-12

    ... Carboxymethylcellulose From Finland, Mexico, Netherlands and Sweden Determinations On the basis of the record \\1... carboxymethylcellulose from Finland and Netherlands would be likely to lead [[Page 27664

  18. Sweden's third national communication on climate change. Under the United Nations framework convention on climate change

    International Nuclear Information System (INIS)

    2001-01-01

    Sweden's national communication to the UN Convention on Climate Change describes everything about the emission and absorption of greenhouse gases, the motives and forces behind emissions, and official Swedish climate policies. Every five years, Sweden submits a communication on practical climate efforts in Sweden to the UN Convention on Climate Change. The Swedish Environmental Protection Board has coordinated the work of producing the basic documentation for the communication, which also describes the measures already taken and those planned for the future. In addition, scenarios have been adopted for developments in Swedish greenhouse gas emissions, Sweden's vulnerability and Swedish research into the climate and climate change

  19. Development of Dalaelven hydro power scheme in Sweden

    International Nuclear Information System (INIS)

    Kokko, Voitto; Hjerthen, Peter; Ingfaelt, Hans; Loewen, Karl-Erik; Sjoegren, Arne

    2015-01-01

    The Dalaelven hydro scheme is located in central Sweden. Fortum has in the scheme 50 dams and 35 hydro power plants producing 4 TWh energy with a capacity of 970 MW. The main reservoirs are Lake Siljan and Traengsletsjoen with Traengslet dam, the highest earth-filled dam in Sweden. Development of the hydro scheme started 1878 with construction of four power plants for industry until 1930. From 1931 to 1974 15 power plants were built for increasing electricity consumption. De-regulation of the energy market in 1990's and EU environmental targets in 2000's resulted in the rehabilitation of ten power plants between 1990 and 2014 with increased annual energy production of 377 GWh (29%) and capacity 124 MW (59%). This energy decreases the annual CO 2 emissions with 125918 tons in comparison to production of the same amount of energy by coal. In several cases the rehabilitation was made in new power houses, allowing the development of the layout and technology of civil structures, and use of state-of-art equipment. Sweden uses the green certificate system, and 235 GWh of the energy received this certificate. Other environmental benefits come from use of the environmentally friendly Kaplan turbines and construction of some new fish pass. There are further plans to increase the spillway capacity of Traengslet dam and to rehabilitate eight power plant units. The possibilities of obtaining the Environmental licences for the rehabilitations has became challenging in the past years and green certificates are nowadays agreed only for increased energy. (authors)

  20. Bioenergy policy and market development in Finland and Sweden

    International Nuclear Information System (INIS)

    Ericsson, Karin; Huttunen, Suvi; Nilsson, L.J.; Svenningsson, Per

    2004-01-01

    The use of biomass in Finland and Sweden has steadily increased over the past 25 years, up to approximately 20% of the primary energy supply in 2001. In both countries most biomass originates from forests. Forest biomass is now an integral part of modern energy systems, although primarily in industry and in the heating sector. For example, biomass accounts for 7.9% and 53% of the fuel mix in district heating in Finland and Sweden, respectively. The general energy policy of both countries has supported biomass for energy over the entire period, although specific policies have changed with time. Research, development and demonstration has been continuously supported, and some subsidy schemes have been applied, in particular, for district heating systems (DHS) and combined heat and power. Heavy taxation of competing fossil fuels seems to have been the most effective policy instrument, although this has been directed mainly at the heat and transportation fuel markets. Electricity taxes are imposed on consumption (industry is largely exempt), and do not discriminate significantly between the sources of electricity. Starting in 2003, Sweden will have a quota-based system, a renewable portfolio standard, which is expected to increase biomass-based electricity production. Both countries possess vast and not fully exploited biomass resources in the form of forests, and have a history of rational and large-scale forestry. Strong actors exist both with regard to forest ownership and the industrial processing of forest products. The user side, in particular, represented by DHS, can also be characterised by strong and professional management. Over time, structures have developed that facilitate an increased use of biomass for energy, for example, the forest industry infrastructure and extensive district heating. Actors within these structures have had the ability to react to policies, resulting in a stable growth in biomass use

  1. Management of low- and intermediate level waste in Sweden

    International Nuclear Information System (INIS)

    Carlsson, Jan

    1999-01-01

    This presentation describes how the management of radioactive waste is organised in Sweden, where Swedish law places the responsibility for such management with the waste generators. The four nuclear utilities have formed a joint company, the Swedish Nuclear Fuel and Waste Management Co., SKB, to handle the nuclear waste. The Swedish waste management system includes a final repository for short-lived low level waste (LLW) and intermediate level waste (ILW) and an interim storage facility for spent nuclear fuel and long-lived waste. Some very low-level, short-lived waste is disposed of in shallow-land repositories at the nuclear power stations. The final repository is situated in underground rock caverns close to the Forsmark nuclear power plant. The rock caverns have been excavated to a depth of more than 50 m beneath the Baltic Sea floor. LLW is compacted into bales or packaged in metal drums or cases that can be transported in standard freight containers. Radioactive materials used in other sectors such as hospitals are collected and packaged at Studsvik and later deposited in the deep repository. ILW is mixed with cement or bitumen and cast in cement or steel boxes or metal drums. The final repository has different chambers for different kinds of waste. The environmental impact of the repository is negligible. Because Sweden's nuclear power plants and the SKB facilities all are located on the coast, all the waste transport can be conducted by sea. The costs of managing and disposing of Sweden's nuclear waste are small compared to the price of electricity

  2. Gout in immigrant groups: a cohort study in Sweden.

    Science.gov (United States)

    Wändell, Per; Carlsson, Axel C; Li, Xinjun; Gasevic, Danijela; Ärnlöv, Johan; Holzmann, Martin J; Sundquist, Jan; Sundquist, Kristina

    2017-05-01

    Our aim was to study the association between country of birth and incidence of gout in different immigrant groups in Sweden. The study population included the whole population of Sweden. Gout was defined as having at least one registered diagnosis in the National Patient Register. The association between incidence of gout and country of birth was assessed by Cox regression, with hazard ratios (HRs) and 95% confidence intervals (95% CI), using Swedish-born individuals as referents. All models were conducted in both men and women, and the full model was adjusted for age, place of residence in Sweden, educational level, marital status, neighbourhood socio-economic status and co-morbidities. The risk of gout varied by country of origin, with highest estimates, compared to Swedish born, in fully adjusted models among men from Iraq (HR 1.82, 95% CI 1.54-2.16), and Russia (HR 1.69, 95% CI 1.26-2.27), and also high among men from Austria, Poland, Africa and Asian countries outside the Middle East; and among women from Africa (HR 2.23, 95% CI 1.50-3.31), Hungary (HR 1.98, 95% CI 1.45-2.71), Iraq (HR 1.76, 95% CI 1.13-2.74) and Austria (HR 1.70, 95% CI 1.07-2.70), and also high among women from Poland. The risk of gout was lower among men from Greece, Spain, Nordic countries (except Finland) and Latin America and among women from Southern Europe, compared to their Swedish counterparts. The increased risk of gout among several immigrant groups is likely explained by a high cardio-metabolic risk factor pattern needing attention.

  3. Oil spill R ampersand D efforts in Sweden

    International Nuclear Information System (INIS)

    Thorell, D.; Jansson, B.

    1992-01-01

    Let me at first mention some significant facts of the Baltic Sea and of Sweden. It has an average depth of only 60 to 70 meters.The waters are low in temperature as well as low in oxygen and salt content (salinity). The air-temperature is in the winter often lower than minus 20 degrees C. The entrance to the Baltic is very narrow and shallow, which means that it takes thirty years before the water in the Baltic is completely renewed. This makes the Baltic Sea to the world's largest brackish water area where the organisms are very vulnerable and sensitive to all kinds of pollution. Oil spills pose a special threat. Every year, approximately 45 million tons of oil of all types crude, bunker, diesel - to name some - are transported through Swedish waters. The shipping of oil in other parts of the Baltic Sea exceeds this figure; a shipping not subject to our legislation but from time to time, with its spills polluting our environment. Sweden has an extremely long coastline to protect: 14,000 kilometers (nearly 9,000 miles) along the mainland plus the shores of more than 100,000 islands. Some oil spills have contaminated more than 12,000 islands which have large bird and seal populations and are public recreation areas for 1 million people and pleasure boats. Sweden started a comprehensive oil spill R ampersand D programme in 1982. This programme, introduced in this document, is now ended and strategies for the twenty-first century are now being drawn up

  4. Nuclear safety culture in Finland and Sweden - Developments and challenges

    Energy Technology Data Exchange (ETDEWEB)

    Reiman, T.; Pietikaeinen, E. (Technical Research Centre of Finland, VTT (Finland)); Kahlbom, U. (RiskPilot AB (Sweden)); Rollenhagen, C. (Royal Institute of Technology (KTH) (Sweden))

    2011-02-15

    The project aimed at studying the concept of nuclear safety culture and the Nordic nuclear branch safety culture. The project also aimed at looking how the power companies and the regulators view the current responsibilities and role of subcontractors in the Nordic nuclear safety culture as well as to inspect the special demands for safety culture in subcontracting chains. Interview data was collected in Sweden (n = 14) and Finland (n = 16) during 2009. Interviewees represented the major actors in the nuclear field (regulators, power companies, expert organizations, waste management organizations). Results gave insight into the nature and evaluation of safety culture in the nuclear industry. Results illustrated that there is a wide variety of views on matters that are considered important for nuclear safety within the Nordic nuclear community. However, the interviewees considered quite uniformly such psychological states as motivation, mindfulness, sense of control, understanding of hazards and sense of responsibility as important for nuclear safety. Results also gave insight into the characteristics of Nordic nuclear culture. Various differences in safety cultures in Finland and Sweden were uncovered. In addition to the differences, historical reasons for the development of the nuclear safety cultures in Finland and Sweden were pointed out. Finally, results gave implications that on the one hand subcontractors can bring new ideas and improvements to the plants' practices, but on the other hand the assurance of necessary safety attitudes and competence of the subcontracting companies and their employees is considered as a challenge. The report concludes that a good safety culture requires a deep and wide understanding of nuclear safety including the various accident mechanisms of the power plants as well as a willingness to continuously develop one's competence and understanding. An effective and resilient nuclear safety culture has to foster a constant

  5. Nuclear safety culture in Finland and Sweden - Developments and challenges

    International Nuclear Information System (INIS)

    Reiman, T.; Pietikaeinen, E.; Kahlbom, U.; Rollenhagen, C.

    2011-02-01

    The project aimed at studying the concept of nuclear safety culture and the Nordic nuclear branch safety culture. The project also aimed at looking how the power companies and the regulators view the current responsibilities and role of subcontractors in the Nordic nuclear safety culture as well as to inspect the special demands for safety culture in subcontracting chains. Interview data was collected in Sweden (n = 14) and Finland (n = 16) during 2009. Interviewees represented the major actors in the nuclear field (regulators, power companies, expert organizations, waste management organizations). Results gave insight into the nature and evaluation of safety culture in the nuclear industry. Results illustrated that there is a wide variety of views on matters that are considered important for nuclear safety within the Nordic nuclear community. However, the interviewees considered quite uniformly such psychological states as motivation, mindfulness, sense of control, understanding of hazards and sense of responsibility as important for nuclear safety. Results also gave insight into the characteristics of Nordic nuclear culture. Various differences in safety cultures in Finland and Sweden were uncovered. In addition to the differences, historical reasons for the development of the nuclear safety cultures in Finland and Sweden were pointed out. Finally, results gave implications that on the one hand subcontractors can bring new ideas and improvements to the plants' practices, but on the other hand the assurance of necessary safety attitudes and competence of the subcontracting companies and their employees is considered as a challenge. The report concludes that a good safety culture requires a deep and wide understanding of nuclear safety including the various accident mechanisms of the power plants as well as a willingness to continuously develop one's competence and understanding. An effective and resilient nuclear safety culture has to foster a constant sense of

  6. Some remarks about remedial actions and research program in Sweden

    International Nuclear Information System (INIS)

    Ericson, S.O.

    1980-01-01

    In the fall of 1978 six houses in Sweden were found to have unacceptably high radon concentrations. These houses were built on land where shale ash had been used as landfill. Radon levels were reduced significantly by increasing ventilation rates or by removing the shale ash. In five houses built of aerated concrete based on alum shale attempts are being made to reduce the radon concentration by papering the walls with aluminum foil. Further work is being done on the relation between elevated activity in rock and soil and indoor concentrations of radon, and on the exhalation of radon from building materials

  7. No opt-out is forever. Sweden opts back in

    International Nuclear Information System (INIS)

    Schneider, Horst

    2010-01-01

    The draft legislation by the conservative-liberal Swedish government of early 2010, which was adopted by the Swedish parliament on June 17, 2010, not only repeals the shutdown of all Swedish nuclear power plants, which had earlier been foreseen by this year, but permits the construction and operation of new plants. In Sweden, a referendum in 1980 started the opt-out process. Shutdown within 30 years was foreseen in the regulation. As early as in late 1995, an Energy Committee appointed by the government reported that a complete opt-out by 2010 was impossible to achieve on economic and environmental grounds. Under the 1997 Opt-out Act, the government may shut down nuclear power plants at any time against an indemnification - unlike Germany. Another prerequisite is the realistic availability of new energy sources. As a consequence, only 2 nuclear power plants have been shut down so far, mainly because of protests from neighboring Denmark. Thirty years after the referendum, the acceptance of nuclear power in Sweden is high and stable. In line with growing public acceptance in the course of the debate about climate change, the Christian-Democratic Party changed its policy in March 2007, opting out of the opt-out. Finally, the conservative-liberal Swedish government submitted draft legislation to parliament which also permitted building new nuclear power plants. The Social Democratic Workers' Party, which is in the opposition, stuck to its rejection of the use of nuclear power and announced its intention to reverse the repeal of the opt-out in September 2010, after parliamentary elections and a possible new red-green government. The public and political developments in Sweden show that social attitudes towards nuclear power, opt-out policies and legal regulations can change. Adopting a rational attitude when discussing nuclear power and realities is possible, and political views sooner or later will adapt to the new situation. This could happen also in Germany

  8. Apartment price determinants : A comparison between Sweden and Germany

    OpenAIRE

    Anop, Sviatlana

    2015-01-01

    Similar development of economic fundamentals in Germany over the last two decades did not lead to the same dramatic house price increases as it is in Sweden. What can explain this house price stability over a long period? This thesis attempts to find the answer this question. The first paper in this thesis contains an extended literature review on the studies focused on the factors affecting house prices in the short and in the long run. Existing literature adopts a broad variation of approac...

  9. The principle of public access to official documents in Sweden

    International Nuclear Information System (INIS)

    Persson, I.

    2001-01-01

    In Sweden, access to information is considered one of the cornerstones of the free democratic exchange of views. It is not enough that public authorities give information about their work. Public activities shall be open to the citizens and the media in such a way that they can choose the information they wish to obtain, without having to rely on public information services. An official document is public, it must be kept available to anyone who wishes to peruse it. Official documents are registered in a public register in order to allow to anyone to exercise their right of access to official document. (N.C.)

  10. Gas turbine installations in nuclear power plants in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Sevestedt, Lars [Electrical Equipment and Gas Turbines, Swedish State Power Board, Ringhals Nuclear Power Plant, S-430 22 Vaeroebacka (Sweden)

    1986-02-15

    At each of the four nuclear power stations in Sweden (Ringhals, Forsmark, Oskarshamn, Barsebaeck) gas turbine generating sets have been installed. These units are normally used for peak load operation dictated of grid and System requirements but they are also connected to supply the electrical auxiliary load of the nuclear plant as reserve power sources. The gas turbines have automatic start capability under certain abnormal conditions (such as reactor trips, low frequency grid etc) but they can also be started manually from several different locations. Starting time is approximately 2- 3 minutes from start up to full load. (author)

  11. Prenatal diagnosis in Sweden: organisation and current issues.

    Science.gov (United States)

    Bui, T H; Kristoffersson, U

    1997-01-01

    Invasive prenatal diagnosis was introduced in Sweden in the early 1970s and is an integral part of the public health care system. Funding is provided by taxation; the patient only pays a consultation fee. Genetic analyses on a broad range of cytogenetic and molecular disorders are performed at the 6 university-affiliated hospitals and in 1 county hospital. About 6% of all newborns have been cytogenetically screened during pregnancy, and about 90% of the analyses are performed after amniocentesis. The main indication is chromosome analysis because of advanced maternal age.

  12. Optimal localisation of next generation Biofuel production in Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Wetterlund, Elisabeth [Linkoeping Univ., Linkoeping (Sweden); Pettersson, Karin [Chalmers Univ. of Technology, Goeteborg (Sweden); Mossberg, Johanna [SP Technical Research Inst. of Sweden, Boraas (Sweden)] [and others

    2013-09-01

    With a high availability of lignocellulosic biomass and various types of cellulosic by-products, as well as a large number of industries, Sweden is a country of great interest for future large scale production of sustainable, next generation biofuels. This is most likely also a necessity as Sweden has the ambition to be independent of fossil fuels in the transport sector by the year 2030 and completely fossil free by 2050. In order to reach competitive biofuel production costs, plants with large production capacities are likely to be required. Feedstock intake capacities in the range of about 1-2 million tonnes per year, corresponding to a biomass feed of 300-600 MW, can be expected, which may lead to major logistical challenges. To enable expansion of biofuel production in such large plants, as well as provide for associated distribution requirements, it is clear that substantial infrastructure planning will be needed. The geographical location of the production plant facilities is therefore of crucial importance and must be strategic to minimise the transports of raw material as well as of final product. Competition for the available feedstock, from for example forest industries and CHP plants (combined heat and power) further complicates the localisation problem. Since the potential for an increased biomass utilisation is limited, high overall resource efficiency is of great importance. Integration of biofuel production processes in existing industries or in district heating systems may be beneficial from several aspects, such as opportunities for efficient heat integration, feedstock and equipment integration, as well as access to existing experience and know-how. This report describes the development of Be Where Sweden, a geographically explicit optimisation model for localisation of next generation biofuel production plants in Sweden. The main objective of developing such a model is to be able to assess production plant locations that are robust to varying

  13. NSFR Seminar 2014 – National Report for Sweden

    Directory of Open Access Journals (Sweden)

    Kleist David

    2014-11-01

    Full Text Available This article aims to give an overview of the rules concerning taxation of companies in Sweden and of trends in the taxation of companies that have been evident in the last few years. It focuses in particular on issues that are connected with the so-called BEPS discussion, for instance interest deduction limitations, CFC rules, general anti-avoidance rules and other rules intended to protect the national tax base. It also sets out to describe other important features of the Swedish tax legislation in regard to companies, such as the rules on taxation of inbound and outbound dividends, interest and royalty.

  14. Regulatory aspects on underground disposal of radioactive waste in Sweden

    International Nuclear Information System (INIS)

    Larsson, A.

    1978-01-01

    The underground disposal of radioactive waste in Sweden is primarily governed by the Atomic Energy Act, the Radiation Protection Act, and to some extent by the Nuclear Liability Act. The regulatory authorities in question are the Nuclear Power Inspectorate, and the Radiation protection Institute. Application for a licence relating to waste management facilities are examined by the Inspectorate which presents its recommendations to the Government for decision. The Inspectorate is also called upon to impose conditions for the operation of the installation. The choice of site for the proposed nuclear waste facility is subject to the approval of the local authorities concerned. (NEA) [fr

  15. Gas turbine installations in nuclear power plants in Sweden

    International Nuclear Information System (INIS)

    Sevestedt, Lars

    1986-01-01

    At each of the four nuclear power stations in Sweden (Ringhals, Forsmark, Oskarshamn, Barsebaeck) gas turbine generating sets have been installed. These units are normally used for peak load operation dictated of grid and System requirements but they are also connected to supply the electrical auxiliary load of the nuclear plant as reserve power sources. The gas turbines have automatic start capability under certain abnormal conditions (such as reactor trips, low frequency grid etc) but they can also be started manually from several different locations. Starting time is approximately 2- 3 minutes from start up to full load. (author)

  16. Accident management strategy in Sweden - implementation and verification

    International Nuclear Information System (INIS)

    Loewenhielm, Gustaf; Engqvist, Alf; Espefaelt, Ralf

    1994-01-01

    A comprehensive program for severe accident mitigation was completed in Sweden by the end of 1988. As described in this paper, this program included plant modifications such as the introduction of filtered containment venting, and an accident management system comprising emergency operating strategies and procedures, training and emergency drills. The accident management system at Vattenfall has been further developed since 1988 and some results and experience from this development are reported in this paper. The main aspects covered concern the emergency organization and the supporting tools developed for use by the emergency response teams, the radiological implications such as accessibility to various locations and the long-term aspects of accident management. ((orig.))

  17. The concept of visitors' centres: a mobile alternative from Sweden

    International Nuclear Information System (INIS)

    Ungermark, S.

    1993-01-01

    The information activities at the permanent exhibitions at the four nuclear facility sites in Sweden have been enhanced during the last four years by travelling exhibitions touring the whole country. In this way it has been possible to communicate the most important facts about radioactive waste management to more than 100 000 Swedes annually, i.e. more people than visit all the permanent visitors'centres each year. Also these efforts have opened a dialogue between the general public and the very technicians and scientists who work daily with handling the radioactive waste and planning its future management

  18. Sweden's Cooperation with Eastern Europe in Radiation Safety 2010

    International Nuclear Information System (INIS)

    Van Dassen, Lars; Andersson, Sarmite; Bejarano, Gabriela

    2011-09-01

    The Swedish Radiation Safety Authority implemented in 2010 cooperation projects in Russia, Ukraine, Georgia, Armenia, Lithuania and Moldova based on instructions from the Swedish Government and agreements with the European Union and the Swedish International Development Cooperation Agency, SIDA. The projects aim at achieving a net contribution to radiation safety (including nuclear safety, nuclear security and non-proliferation as well as radiation protection and emergency preparedness) for the benefit of the host country as well as Sweden. This report gives an overview of all the projects implemented in 2010

  19. Heat transfer in underground heating experiments in granite, Stipa, Sweden

    International Nuclear Information System (INIS)

    Chan, T.; Javandel, I.; Witherspoon, P.A.

    1980-04-01

    Electrical heater experiments have been conducted underground in granite at Stripa, Sweden, to investigate the effects of heating associated with nuclear waste storage. Temperature data from these experiments are compared with closed-form and finite-element solutions. Good agreement is found between measured temperatures and both types of models, but especially for a nonlinear finite-element heat conduction model incorporating convective boundary conditions, measured nonuniform initial rock temperature distribution, and temperature-dependent thermal conductivity. In situ thermal properties, determined by least-squares regression, are very close to laboratory values. A limited amount of sensitivity analysis is undertaken

  20. Fuel options for public bus fleets in Sweden

    OpenAIRE

    Xylia, Maria; Silveira, Semida

    2015-01-01

    The Swedish public transport sector has defined two major targets, i.e., to run 90% of the total vehicle kilometers of the fleet on non-fossil fuels and double the volume of travel via public transport by 2020, increasing the share of public transport in relation to the total personal transport in the country . The f3 report Fuel options for public bus fleets in Sweden highlights the challenges and solutions encountered, particularly when it comes to the adoption of renewable fuels in the reg...

  1. Awareness of antibiotic resistance and antibiotic prescribing in UTI treatment: a qualitative study among primary care physicians in Sweden.

    Science.gov (United States)

    Björkman, Ingeborg; Berg, Johanna; Viberg, Nina; Stålsby Lundborg, Cecilia

    2013-03-01

    To improve education and information for general practitioners in relation to rational antibiotic prescribing for urinary tract infection (UTI), it is important to be aware of GPs' views of resistance and how it influences their choice of UTI treatment. The aim of this study was to explore variations in views of resistance and UTI treatment decisions among general practitioners (GPs) in a county in Sweden. Qualitative, semi-structured interviews were analysed with a phenomenographic approach and content analysis. Primary care in Kronoberg, a county in southern Sweden. Subjects. A purposeful sample of 20 GPs from 15 of 25 health centres in the county. The variation of perceptions of antibiotic resistance in UTI treatment. How UTIs were treated according to the GPs. Three different ways of viewing resistance in UTI treatment were identified. These were: (A) No problem, I have never seen resistance, (B) The problem is bigger somewhere else, and (C) The development of antibiotic resistance is serious and we must be careful. Moreover, GPs' perceptions of antibiotic resistance were mirrored in how they reported their treatment of UTIs in practice. There was a hierarchal scale of how GPs viewed resistance as an issue in UTI treatment. Only GPs who expressed concerns about resistance followed prescribing guidelines completely. This offers valuable insights into the planning and most likely the outcome of awareness or educational activities aimed at changed antibiotic prescribing behaviour.

  2. Sweden and the NEGP: A Pilot Study of the North European Gas Pipeline and Sweden's Dependence on Russian Energy

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, Robert L

    2006-06-15

    Developments between 2004 and 2006 indicate that a North European Gas Pipeline (NEGP) through the Baltic Sea, from Russia to Germany, may be realised in the coming decade. This would provide Europe with yet another opportunity to diversify its import channels of gas. It is however reasonable to assume that the NEGP also could change the strategic pattern and be a source of friction. The NEGP may rock the regional stability and reduce the potential of the new EU members to become security providers in Europe's northern dimension. It also gives increased leverage and influence to Russia, a state that has moved in an authoritarian direction under President Putin. The aim of this pilot study is to elucidate on the NEGP pipeline and Sweden's increasing dependence on Russian energy. A subsidiary aim is to outline a set of concerns that have bearing on the situation for the EU and Baltic Sea Region and that need to be further addressed. In conclusion, the NEGP will enhance Russia's direct leverage on Poland, Ukraine, and Belarus, as it will allow Russia to turn off gas supplies without affecting exports to other parts of Europe. Russia will also increase its leverage over the states that will or may be connected to the NEGP (Germany, and possibly Belgium, Denmark, the Netherlands and the UK). Even if Sweden is not embracing the NEGP, it is today highly sensitive as it imports most of its energy. It is increasingly dependent on Russian oil and is partly dependent on imports of electricity from Russia. Should the NEGP materialise and Sweden becomes connected in the future, it would likely be dependent also on natural gas. It is of paramount importance for the energy security of the connected states how the pipeline is constructed and operated. If there will be technical possibilities for Russia to tamper with the flow of gas to individual states without affecting supply to others, there are tangible threats to the importing states.

  3. Sweden and the NEGP: A Pilot Study of the North European Gas Pipeline and Sweden's Dependence on Russian Energy

    International Nuclear Information System (INIS)

    Larsson, Robert L.

    2006-06-01

    Developments between 2004 and 2006 indicate that a North European Gas Pipeline (NEGP) through the Baltic Sea, from Russia to Germany, may be realised in the coming decade. This would provide Europe with yet another opportunity to diversify its import channels of gas. It is however reasonable to assume that the NEGP also could change the strategic pattern and be a source of friction. The NEGP may rock the regional stability and reduce the potential of the new EU members to become security providers in Europe's northern dimension. It also gives increased leverage and influence to Russia, a state that has moved in an authoritarian direction under President Putin. The aim of this pilot study is to elucidate on the NEGP pipeline and Sweden's increasing dependence on Russian energy. A subsidiary aim is to outline a set of concerns that have bearing on the situation for the EU and Baltic Sea Region and that need to be further addressed. In conclusion, the NEGP will enhance Russia's direct leverage on Poland, Ukraine, and Belarus, as it will allow Russia to turn off gas supplies without affecting exports to other parts of Europe. Russia will also increase its leverage over the states that will or may be connected to the NEGP (Germany, and possibly Belgium, Denmark, the Netherlands and the UK). Even if Sweden is not embracing the NEGP, it is today highly sensitive as it imports most of its energy. It is increasingly dependent on Russian oil and is partly dependent on imports of electricity from Russia. Should the NEGP materialise and Sweden becomes connected in the future, it would likely be dependent also on natural gas. It is of paramount importance for the energy security of the connected states how the pipeline is constructed and operated. If there will be technical possibilities for Russia to tamper with the flow of gas to individual states without affecting supply to others, there are tangible threats to the importing states

  4. Grand Advantage: Family Wealth and Grandchildren's Educational Achievement in Sweden.

    Science.gov (United States)

    Hällsten, Martin; Pfeffer, Fabian T

    2017-04-01

    We study the role of family wealth for children's educational achievement using novel and unique Swedish register data. In particular, we focus on the relationship between grandparents' wealth and their grandchildren's educational achievement. Doing so allows us to reliably establish the independent role of wealth in contributing to long-term inequalities in opportunity. We use regression models with rich controls to account for observed socioeconomic characteristics of families, cousin fixed effects to net out potentially unobserved grandparental effects, and marginal structural models to account for endogenous selection. We find substantial associations between grandparents' wealth and their grandchildren's grade point averages (GPA) in the 9th grade that are only partly mediated by the socioeconomic characteristics and wealth of parents. Our findings indicate that family wealth inequality - even in a comparatively egalitarian context like Sweden - has profound consequences for the distribution of opportunity across multiple generations. We posit that our estimates of the long-term consequences of wealth inequality may be conservative for nations other than Sweden, like the United States, where family wealth - in addition to its insurance and normative functions - allows the direct purchase of educational quality and access.

  5. Sweden beyond oil: nuclear commitments and solar options

    International Nuclear Information System (INIS)

    Loennroth, M.; Johansson, T.B.; Steen, P.

    1982-01-01

    The paper argues that both a nuclear and a solar future are technically possible, but that institutional differences are vast. There is a consensus in Sweden to keep long term options open. Approaches are identified that will allow Sweden to postpone as many decisions as possible as to which path to follow. Decentralized systems require emphasis on local planning, and will require substantial expansions of authority of local planners. A nuclear future would require substantial increases in central planning and would also require substantial institutional change if most energy is to be provided by nuclear energy in 2015. The primary near term reform needed to maintain maximum flexibility includes: (1) strengthening of local authority, especially in areas relating to district heating and conservation; (2) regulatory reform to assure adequate financing on the local level, and to assure adequate balancing of conservation and supply financing; (3) increased national control over large energy users; (4) state financed procurement and development of new energy technologies, especially smaller scale technologies; (5) national land use planning; (6) electric utility reform to encourage dispersed electric technologies

  6. Structural health monitoring of a concrete bridge in Sweden

    Science.gov (United States)

    Enochsson, Ola; Täljsten, Björn; Olofsson, Thomas

    2006-03-01

    Over the past decade the interests in upgrading, assessment and maintenance of our ageing infrastructure has grown avalanche-like. The main reason is economical aspects but also reasons due to accessibility environmental consideration play a vital role. Recently the Swedish and Norwegian Railway Association decided to upgrade the Iron Ore Line "Malmbanan", a railway line for transportation of iron from northern Sweden to the coasts of Norway and Sweden. Here the owner wanted to increase the axle loads from 25 to 30 tons to reduce the transportation costs. In one of the cases, the Luossajokk Bridge, a recalculation according to design codes showed that the increased axle loads would exceed the yield limit in the reinforcement. Before any decision was taken regarding strengthening or replacing the bridge an assessment with probabilistic methods was used. It appeared that the bridge could carry the higher load with a safety index β >= 4.7 for reasonable assumptions of the load distributions. A measurement system was installed to check the real worst placement of the new iron ore locomotive (IORE), and the actually level of strains in the reinforcement for the worst load case1. It was shown that the strain level was far from critical and that the evaluated worst placement of the locomotive was almost correct. To assure a reliable transportation a long term monitoring program was arranged to check the development of strains with time. Examples from the probabilistic evaluation and the monitoring of the bridge are given and discussed.

  7. 137Cs in the population of northern Sweden

    International Nuclear Information System (INIS)

    Aagren, G.; Bjoereland, A.; Johansson, Lennart.

    1996-12-01

    The activity of Cs 137 has been studied in several different population groups in northern Sweden after the Chernobyl accident. Special attention has been given to the Saami (Lapp) population from which we have measured a group of volunteers regularly between 1986 and 1990. In 1991 we started a study on randomly chosen groups from the general population and members of the Saami communities from three regions in northern Sweden with different deposition levels. The results from these measurements have shown an effective half-time of Cs whole-body content in the Saami groups of about five years. The measurements in 1996 show decreasing levels of activities in the different population groups with half-times between 4 and 12 years. Another exposed group is breast-fed babies. We have measured the transfer of Cs from mother to baby via the breast milk in 12 cases. The activity in breast milk was measured to be 14% of the activity in the mother (calculated using specific activity - Bq/kg). The corresponding activity in the baby was 90% of the activity in the mother. 13 refs

  8. Overview of plant reliability and aging in Sweden

    International Nuclear Information System (INIS)

    Eckered, T.

    1985-01-01

    In a wide sense aging includes all the phenomena that cause properties of a system to deviate from those existing at the time of start of operation of the system. Such phenomena are of course those well known ones as corrosion, erosion, fatigue and wear. But other phenomena can be included like technological development making original designs obsolete or the learning or forgetting of operators. In this presentation the Swedish nuclear power programme will be briefly described, especially as concerns different generations of nuclear reactors and their operation history. Operating experience, including scram statistics and trends, will be covered as well as availability and reliability as functions of plant age and plant generation. Specific aging phenomena which have been experienced in Sweden, will be described as well as the actions taken or planned for coping with them. The means and tools used in Sweden for tracking aging phenomena will also be covered. The question is posed whether we need an international data bank for aging, maintenance and repair information similar to the already existing, successful incident data banks

  9. SWEDEN--RECENT CHANGES IN WELFARE STATE ARRANGEMENTS.

    Science.gov (United States)

    Burström, Bo

    2015-01-01

    The Swedish welfare state, once developed to create a new society based on social equality and universal rights, has taken on a partly new direction. Extensive choice reforms have been implemented in social services and an increasing proportion of tax-funded social services, including child day care, primary and secondary schools, health care, and care of the elderly, is provided by private entrepreneurs, although funded by taxes. Private equity firms have gained considerable profits from the welfare services. The changes have taken place over a 20-year period, but at an accelerated pace in the last decade. Sweden previously had very generous sickness and unemployment insurance, in terms of both duration and benefit levels, but is falling behind in terms of generosity, as indicated by increasing levels of relative poverty among those who depend on benefits and transfers. Increasing income inequality over the past 20 years further adds to increasing the gaps between population groups. In some respects, Sweden is becoming similar to other Organisation for Economic Co-operation and Development countries. The article describes some of the changes that have occurred. However, there is still widespread popular support for the publicly provided welfare state services.

  10. Consequences for wind power in Sweden of climatic changes

    International Nuclear Information System (INIS)

    Hovsenius, Gunnar; Kjellstroem, Erik

    2007-05-01

    In an earlier report to Elforsk SMHI has calculated that a total installed effect of 4000 MW in wind mills in Sweden will as an annual average generate approximately 10 TWh of electricity during the period of 1992 - 2001. These estimates has an uncertainty of ±5 %. The calculations are related to a scenario with 56 larger wind mill farms of which an essential part is located to the southern part of Sweden and to off shore installations. This study is aimed to investigate if a climate change in a future of 20 - 30 years from now will influence the wind power generation compared to the earlier study. The views of the future wind energy which are presented in this study are partly based on calculations performed at Rossby Centre, SMHI, partly on other reported studies. The calculations performed at Rossby Centre originate from three of the emission scenarios - A1B, A2 and B2 - presented by the International Panel on Climate Change, IPCC. The differences between these scenarios are marginal for the next 20-30 years. The calculations are also based on a regional climate model developed at the Rossby Centre, which has been widely accepted in the science. The boundary conditions used to the regional model are generated from two global circulation models developed at Max-Planck Institute for Meteorology in Hamburg. This study can be concluded in the following four points: 1. The generation of electricity from wind mills may increase by 5 - 20 % within a period of 20 - 30 years from now, compared to the period 1992 - 2001 or from 10 up to about 12 TWh per annum. A long-term increase of the wind energy in the region of the Baltic Sea seems to be a trend in several of the scientific well reputed global circulation models. 2. The energy content of the wind has during the last century varied approximately with ± 10 % in Sweden and in the region of the Baltic Sea. For the period of 1992- 2001 the energy content of the wind however decreased. If the estimated increase in wind

  11. Blood Versus Land: The Comparative Foundations for Citizenship and Voting Rights in Germany and Sweden

    Science.gov (United States)

    2010-03-01

    Sweden After 1866," in How Did They Become Voters? The History of Franchise in Modern European Representation, ed. Raffaele Romanelli, 341–372 (Boston...Andersson, Lars I. "How Did They Become Voters: Sweden After 1866." In How Did They Become Voters? The History of Franchise in Modern European

  12. Students' Perceptions of Assessment: A Comparative Analysis between Portugal and Sweden

    Science.gov (United States)

    Pereira, Diana; Niklasson, Laila; Flores, Maria Assunção

    2017-01-01

    This paper aims at investigating students' perceptions about assessment, especially the ways in which it is put into practice. Data were collected through questionnaires in different programmes in Portugal and Sweden. In total, 173 students from Portugal and 72 from Sweden participated in the study. Findings showed that students had similar ideas…

  13. Subarachnoid haemorrhage in Sweden 1987-2002 : regional incidence and case fatality rates

    NARCIS (Netherlands)

    Koffijberg, H.; Buskens, E.; Granath, F.; Adami, J.; Ekbom, A.; Rinkel, G. J. E.; Blomqvist, P.

    Background: Incidence estimates of subarachnoid haemorrhage (SAH) in Sweden vary, which may be caused by regional variations. Reliable estimates of age-specific case fatality rates are lacking. We analysed regional incidence rates and case fatality rates of SAH in Sweden. Methods: The Swedish

  14. Trends in occupational mortality among middle-aged men in Sweden 1961-1990

    DEFF Research Database (Denmark)

    Diderichsen, Finn; Hallqvist, J

    1997-01-01

    Many European countries have in recent decades reported growing socioeconomic differentials in mortality. While these trends have usually paralleled high unemployment and increasing income disparities, Sweden had low unemployment and narrowing income differences. This study describes trends, 1961......-1990, in total and cardiovascular mortality among men, 45-69 years of age, in major occupational classes in Sweden....

  15. Second Chance Education Matters! Income Trajectories of Poorly Educated Non-Nordics in Sweden

    Science.gov (United States)

    Nordlund, Madelene; Bonfanti, Sara; Strandh, Mattias

    2015-01-01

    In this study we examine the long-term impact of second chance education (SCE) on incomes of poorly educated individuals who live in Sweden but were not born in a Nordic country, using data on income changes from 1992 to 2003 compiled by Statistics Sweden. Ordinary Least Squares regression analyses show that participation in SCE increased the work…

  16. Crown condition dynamics of oak in southern Sweden 1988-1999.

    Science.gov (United States)

    Drobyshev, Igor; Anderson, Stefan; Sonesson, Kerstin

    2007-11-01

    Crown defoliation of oak (Quercus robur and Q. petraea) was analysed in 808 trees during three forest condition surveys (1988, 1993, and 1999) in the southern Sweden. From 1988 to 1999 crown defoliation increased by more than 20%. Changes in crown defoliation were related to the pH in the upper 20-30 cm of the mineral soils, which was closely connected to other measures of soil fertility (cation exchange capacity, CEC and C/N ratio). Trees growing on soils with a high pH (> or =4.00, in BaCl2 filtrate), high CEC and low C/N ratio had significantly lower crown defoliation than trees growing on more acid soils (pH trees with respect to crown defoliation, indicating that decline in crown condition was not due to an age-related increase in crown transparency. Considering only trees younger than 100 years, a significant interaction was observed between changes in crown defoliation and soil pH. Trees younger than 100 years old growing on more acidic soils had a greater increase in crown transparency than trees on more basic soils between 1988 and 1999. Trees > or =100 years old had significantly higher defoliation on more acidic than on more basic soils, however defoliation dynamics of these trees over 1988-99 was not related to soil acidity. Two biotic agents (insect and fungal leaf infections) evaluated in this study did not prove to be important drivers of defoliation dynamics.

  17. Barriers to Trace-back in a Salad-associated EHEC Outbreak, Sweden, June 2013.

    Science.gov (United States)

    Edelstein, Michael; Sundborger, Camilla; Hergens, Maria-Pia; Ivarsson, Sofie; Dryselius, Rikard; Insulander, Mona; Jernberg, Cecilia; Hutin, Yvan; Wallensten, Anders

    2014-06-06

    In June-July 2013, six counties notified the Swedish Institute for Communicable Disease Control of enterohaemorrhagic E.coli (EHEC) infections among attendees at a hotel in Dalarna, Sweden. An outbreak control team investigated to identify the source and implement control measures. We included individuals who attended the hotel between June 19th-25th in a cohort. We asked them about animal contact, swimming, and consumption of food items during this time using a questionnaire. A confirmed case was an EHEC O157:H7 outbreak strain positive individual who developed abdominal pain or diarrhoea between June 20th-July 2nd. We described the outbreak in time, place and person, calculated risk ratios (RR) and 95% confidence intervals (CI). We investigated the kitchen, tested and traced back implicated food items. 172 individuals responded. We identified 19 confirmed cases (Median age: 17 years, 64% female) with symptom onset between June 22nd-27th. Eating green salad on June 20th was associated with illness (RR:3.7;CI:1.3-11). The kitchen mixed green salads without records and destroyed leftovers immediately. Hence we could not conduct trace-back or obtain microbiological confirmation. Green salad contaminated before entering the kitchen was the likely outbreak source. We recommended early collaboration with food agencies and better restaurant records to facilitate future investigations.

  18. Pinworm Infection

    Science.gov (United States)

    Pinworm infection Overview Pinworm infection is the most common type of intestinal worm infection in the United States and one of the most common worldwide. Pinworms are thin and white, measuring about 1/4 ...

  19. Risk factors and potential preventive measures for nephropatia epidemica in Sweden 2011–2012: a case–control study

    Directory of Open Access Journals (Sweden)

    Alin Gherasim

    2015-06-01

    Full Text Available Introduction: Nephropatia epidemica (NE, a relatively mild form of hemorrhagic fever with renal syndrome caused by the Puumala virus (PUUV, is endemic in northern Sweden. We aim to study the risk factors associated with NE in this region. Methods: We conducted a matched case–control study between June 2011 and July 2012. We compared confirmed NE cases with randomly selected controls, matched by age, sex, and place of infection or residence. We analyzed the association between NE and several occupational, environmental, and behavioral exposures using conditional logistic regression. Results: We included in the final analysis 114 cases and 300 controls, forming 246 case–control pairs. Living in a house with an open space beneath, making house repairs, living less than 50 m from the forest, seeing rodents, and smoking were significantly associated with NE. Conclusion: Our results could orient public health policies targeting these risk factors and subsequently reduce the NE burden in the region.

  20. Etiology and antimicrobial susceptibility of udder pathogens from cases of subclinical mastitis in dairy cows in Sweden

    Directory of Open Access Journals (Sweden)

    Nyman Ann-Kristin J

    2011-06-01

    Full Text Available Abstract Background A nationwide survey on the microbial etiology of cases of subclinical mastitis in dairy cows was carried out on dairy farms in Sweden. The aim was to investigate the microbial panorama and the occurrence of antimicrobial resistance. Moreover, differences between newly infected cows and chronically infected cows were investigated. Methods In total, 583 quarter milk samples were collected from 583 dairy cows at 226 dairy farms from February 2008 to February 2009. The quarter milk samples were bacteriological investigated and scored using the California Mastitis Test. Staphylococci were tested for betalactamase production and presence of resistance was evaluated in all specific udder pathogens. Differences between newly infected cows and chronically infected cows were statistically investigated using logistic regression analysis. Results The most common isolates of 590 bacteriological diagnoses were Staphylococcus (S aureus (19% and coagulase-negative staphylococci (CNS; 16% followed by Streptococcus (Str dysgalactiae (9%, Str. uberis (8%, Escherichia (E. coli (2.9%, and Streptococcus spp. (1.9%. Samples with no growth or contamination constituted 22% and 18% of the diagnoses, respectively. The distribution of the most commonly isolated bacteria considering only bacteriological positive samples were: S. aureus - 31%, CNS - 27%, Str. dysgalactiae - 15%, Str. uberis - 14%, E. coli - 4.8%, and Streptococcus spp. - 3.1%. There was an increased risk of finding S. aureus, Str. uberis or Str. dysgalactiae in milk samples from chronically infected cows compared to findings in milk samples from newly infected cows. Four percent of the S. aureus isolates and 35% of the CNS isolates were resistant to penicillin G. Overall, resistance to other antimicrobials than penicillin G was uncommon. Conclusions Staphylococcus aureus and CNS were the most frequently isolated pathogens and resistance to antimicrobials was rare.