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Sample records for hanoi dispensando corticoides

  1. Tulemusteta koosistumine Hanois / Tõnis Erilaid

    Index Scriptorium Estoniae

    Erilaid, Tõnis, 1943-

    2006-01-01

    Aasia ja Vaikse ookeani riikide majandusühenduse APEC tippkohtumisel Hanois ei saanud põhisündmuseks Põhja-Koread puudutava karmi resolutsiooni vastuvõtmine, vaid hoopis USA ja Venemaa vahelise lepingu allkirjastamine, mis annab võimaluse Venemaale liituda WTO-ga

  2. Corticoids: 60 Years Later a Pending Subject

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    Silvia Gómez Ordóñez

    2007-12-01

    Full Text Available The objective of this article is to make a brief compilation of the physiology of the hypothalamic-pituitary-adrenal axis in order to understandthe role of the exogenous corticoids as therapeutic tools in innumerable pathologies, but when used inappropriately, it can produce important deleterious effects. The history of the corticoids began 164 years ago in 1843 when Thomas Addison described the symptoms of the adrenal gland insufficiency. On September 21st 1948, almost one hundred years after, Dr. Hench injected cortisone for the first time in a patient with arthritis. In 1950 Hench, Kendall and Reichsteinreceived the Nobel Prize in Medicine and Physiology. In the cortex of the adrenal glands, three different hormones are synthesized from cholesterol, and these hormones produce diverseeffects on the homeostasis of the body. The synthetic glucocorticoids are classified by their anti-inflammatory power, half life, and mineralocorticoideffect; they operate in almost every cell through genomic and non genomic mechanismsof action producing different responses. This is the reason of their wide therapeutic effect in respiratory diseases like asthma and COPD,multiple sclerosis, rejection of transplants, among others.

  3. 21 CFR 862.1195 - Corticoids test system.

    Science.gov (United States)

    2010-04-01

    ...) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES Clinical Chemistry Test Systems § 862... measure the levels of corticoids (hormones of the adrenal cortex) in serum and p lasma. Measurements of...

  4. Role and physiological actions of the mineralo-corticoids; Role et actions physiologiques des mineralo-corticoides

    Energy Technology Data Exchange (ETDEWEB)

    Morel, F. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    This review recalls first of all the history of the discovery of aldosterone; it then defines the concept of mineralo-corticoid on the biological level; the physiological effects of aldosterone are compared with those of desoxycorticosterone, which have been known for a long time. The part played by the mineralo-corticoids in maintaining the hydro-mineral balance is then discussed, particularly in the light of information provided by acute deficiency or primitive hyperaldosteronism; the importance of the correlations linking the post-hypophysis and suprarenal is underlined. The possible mechanisms of the action of mineralo-corticoids on the kidney are discussed in greater detail and a general plan of action is proposed. The physiological regulation of the secretion of mineralo-corticoids is then described, and the respective roles played in this secretion by different factors are discussed (ante-hypophysis, corticoids, plasmatic concentration of electrolytes, volume of extracellular liquids, etc...). Finally, the whole problem investigated is placed within the field of homeostasis (377 bibliographical references). (author) [French] Cette revue de la question rappelle d'abord l'historique de la decouverte de l'aldosterone; elle definit ensuite le concept de mineralo-corticoide sur le plan biologique; les effets physiologiques de l'aldosterone sont compares a ceux connus depuis longtemps de la desoxycorticosterone. Le role joue par les mineralo-corticoides dans le maintien de la balance hydrominerale est ensuite discute, notamment a la lumiere des informations fournies par l'insuffisance aigue ou l'hyperaldosteronisme primitif; l'importance des correlations liant posthypophyse et surrenale est soulignee. Les mecanismes possibles de l'action des mineralo-corticoides sur le rein sont discutes avec davantage de details et un schema general d'action est propose. La regulation physiologique de la secretion des mineralo-corticoides

  5. Los corticoides epidurales en el tratamiento de la hernia discal

    OpenAIRE

    Arenas Planelles, Antonio; Pampliega Martínez, T.; Moros García, J.S.; Cisneros Lanuza, María Teresa; Zabalza Hermoso de Mendoza, N.

    1997-01-01

    Se presenta una serie de 233 pacientes diagnosticados de hernia discal lumbar y tratados mediante infiltraciones epidurales de corticoides, asociadas a un programa de rehabilitación realizado a continuación de las inyecciones. Los resultados con dicho tratamiento fueron satisfactorios en un 75% de los casos. Se observó una mejor evolución en pacientes varones, en pacientes cuya profesión conlleva esfuerzo físico, en hernias discales L5-S1, y en aquellos que han seguido un progr...

  6. Prematuridad extrema y uso materno de corticoides antenatal

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    Ramón Acosta Díaz

    2000-12-01

    Full Text Available Con el objetivo de evaluar el uso de corticoides antenatal en las madres con amenaza de parto pretérmino y el efecto sobre los recién nacidos prematuros extremos, se realizó un estudio prospectivo, longitudinal, y analítico entre todos los niños nacidos vivos con edad gestacional menor de 31 semanas y peso inferior a 1 500 g, ocurridos en el Hospital Ginecoobstétrico Provincial Docente "Justo Legón Padilla" de Pinar del Río, desde enero de 1997 hasta julio de 1998. Se estudiaron los 53 niños con estas características. Los datos que se obtuvieron se depositaron en base de datos; para el procesamiento estadístico, se aplicó la prueba de chi cuadrado, con un nivel de significación de p In order to evaluate the antenatal use of adrenal cortex hormones in mothers with preterm delivery threat and its effect on extreme premature infants, it was conducted a prospective, longitudinal and analytical study among the live births with gestational age under 31 weeks and a weight lower than 1 500 g registered at "Justo Legón Padilla" Provincial Gynecoobstetric Teaching Hospital, in Pinar del Río, from January, 1997, to July, 1998. 53 children with these characteristics were studied. The collected data were entered in databases. The chi square test with a level of significance of p<0.05 was used for the statistical processing. Steroids were administered to 32 mothers. A statistically significant reduction of the hyaline membrane disease, the use of ventilation, the complications and mortality was observed with the antenatal use of maternal adrenal cortex hormones. There were no statistically significant differences between the study and the control group as regards sex, mean gestational age (29.0/28.9 weeks and weights (1207.9/1180.0 g.

  7. Corticoides intralesionales en lesiones a células gigantes

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    J.P. Crestanello Nese

    2003-12-01

    Full Text Available Desde su descripción original, las lesiones de células gigantes (LCG han sido entidades controvertidas, desde el punto de vista de su origen, de su comportamiento clínico, de sus características radiográficas e histológicas, así como de su tratamiento. Para su tratamiento se han considerado alternativas quirúrgicas y no quirúrgicas. En este trabajo, se presentan tres nuevos casos de LCG, en los cuales se realizó infiltración intralesional con corticoides como una maniobra previa y complementaria a la quirúrgica. Luego de la infiltración, se observó una disminución del tamaño de las lesiones y un cambio en sus características macroscópicas, se trato por enucleación un caso y por remodelación quirúrgica los dos restantes.Giant cell lesions (GCL have been controversial entities since its original description. Its origin, clinical behavior, radiographic and histological features and also its treatment are polemical. The therapeutic possibilities are surgical or non surgical. In this paper, the intralesional infiltration with steroids is presented like a previous and complementary therapy to surgery alone. Three new cases of GCL are presented. All of them were first treated with intralesional infiltration with steroids. After that,a partial remission and a change of the macroscopic characteristics were observed and one of the lesion was then enucleated while for the others two surgical remodelation were necessary to do.

  8. Classic Tower of Hanoi, Planning Skills, and the Indian Elderly.

    Science.gov (United States)

    Balachandar, R; Tripathi, R; Bharath, S; Kumar, K

    2015-09-01

    Elderly populations are vulnerable to age-related cognitive decline. Planning, a frontal lobe function, is reported to be affected in the elderly population. There is a paucity of studies which assessed planning skills in the elderly Indian population. The present study aimed to examine the utility of the classic Tower of Hanoi in the assessment of planning skills of elderly Indian subjects. A total of 215 (60 of whom were females, all aged 55-80 years) cognitively normal elders and 24 patients with mild Alzheimer's disease were recruited. All subjects provided informed consent and their planning skills were assessed using the classic Tower of Hanoi. Performance at each level was measured by the total time taken to solve, number of moves to solve, and the number of rule violations. Receiver operating characteristic curve analysis was exploratively performed to test the utility of the Tower of Hanoi in differentiating patients with mild Alzheimer's disease from those who were cognitively normal. Performance measures of cognitively normal group steeply worsened with increasing complexity. With receiver operating characteristic curve analysis, patients with mild Alzheimer's disease were poorly differentiated from cognitively normal group according to their Tower of Hanoi performance. The Tower of Hanoi test is of limited value for the assessment of planning skills in the Indian elderly population. There is a need to modify and develop a suitable neuropsychology tool to assess the planning skills of elderly Indian subjects and further validate it.

  9. Experimental magnetism research in Dhaka, Hanoi and Uppsala

    Science.gov (United States)

    Nordblad, Per

    2015-04-01

    Promoting basic science in developing countries is the aim of the International Science Program at Uppsala University, Sweden. This program, that some years ago celebrated its 50th anniversary, has been the main supporting agency of my more than 30 years of collaboration with research groups in Dhaka at Bangladesh University of Engineering and Technology and the Atomic Energy Commission, and research groups in Hanoi at the Vietnamese Academy of Science. Our common research on magnetism and magnetic materials has been built upon: (i) Longer visits (about half of their total PhD studies) by PhD students from Hanoi and Dhaka at Uppsala University that ends by PhD exams from their home Universities; (ii) short time visits (up to 2 months) by senior scientists to Uppsala for discussions and measurements; (iii) short visits by me and colleagues from Uppsala in Hanoi and Dhaka for discussions, workshops and conferences; (iv) mutual visits of scientists from Bangladesh and Vietnam to each other and neighboring countries (mostly India) for specific experiments and learning new methods and (v) some support for purchase of research equipment. The work with Dhaka and Hanoi and other countries has resulted in: development of internationally competitive research groups in Hanoi and Dhaka that independently publish in international journals, several PhDs that continue their work at the home institutes, numerous common publications in international scientific journals and not the least lasting professional and personal connections between scientists in Bangladesh, Vietnam, Thailand, Eritrea, India and Sweden.

  10. Cetoacidosis inducida por corticoides y gatifloxacina en una mujer joven no diabética

    OpenAIRE

    Lavandaio, Hugo; Marcucci, Guillermo; Carminati, Gustavo; Salomón, Susana Elsa; Carena, José Alberto

    2008-01-01

    Objetivo: Comunicar un caso de cetoacidosis inducida por corticoides y gatifloxacina y discutir los mecanismos de esta inusual y seria complicación. Caso clínico: Mujer de 32 años, ingresa por neumonía adquirida en la comunidad de 5 días de evolución. Antecedentes: AR probable diagnosticada 4 meses antes tratada con metotrexate y corticoides intermitente. Examen físico: regular estado general, IMC 21, Tº 38ºC, FR 32/min, derrame pleural derech...

  11. Corticoides intratimpánicos: una revisión sistemática

    OpenAIRE

    González, Rubén; Caro, Jorge

    2007-01-01

    Muchas patologías otológicas como la hipoacusia súbita y la enfermedad de Maniere han sido tratadas con corticoides sistémlcos, los que tienen diversos efectos secundarios potencia/mente graves. Los corticoides intratimpánicos son una alternativa en el tratamiento para estas enfermedades del oído interno, con lo que se podría aumentar su efecto al mejorar el perfil farmacocinético de la droga disminuyendo los efectos adversos sistémicos. Para evaluar la evidencia disponible con respecto a la ...

  12. Trauma center accessibility for road traffic injuries in Hanoi, Vietnam.

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    Nagata, Takashi; Takamori, Ayako; Kimura, Yoshinari; Kimura, Akio; Hashizume, Makoto; Nakahara, Shinji

    2011-09-30

    Rapid economic growth in Vietnam over the last decade has led to an increased frequency of road traffic injury (RTI), which now represents one of the leading causes of death in the nation. Various efforts toward injury prevention have not produced a significant decline in the incidence of RTIs. Our study sought to describe the geographic distribution of RTIs in Hanoi, Vietnam and to evaluate the accessibility of trauma centers to those injured in the city. We performed a cross-sectional study using Hanoi city police reports from 2006 to describe the epidemiology of RTIs occurring in Hanoi city. Additionally, we identified geographic patterns and determined the direct distance from injury sites to trauma centers by applying geographical information system (GIS) software. Factors associated with the accessibility of trauma centers were evaluated by multivariate regression analysis. We mapped 1,271 RTIs in Hanoi city. About 40% of RTIs occurred among people 20-29 years of age. Additionally, 63% of RTIs were motorcycle-associated incidents. Two peak times of injury occurrence were observed: 12 am-4 pm and 8 pm-0 am. "Hot spots" of road traffic injuries/fatalities were identified in the city area and on main highways using Kernel density estimation. Interestingly, RTIs occurring along the two north-south main roads were not within easy access of trauma centers. Further, fatal cases, gender and injury mechanism were significantly associated with the distance between injury location and trauma centers. Geographical patterns of RTIs in Hanoi city differed by gender, time, and injury mechanism; such information may be useful for injury prevention. Specifically, RTIs occurring along the two north-south main roads have lower accessibility to trauma centers, thus an emergency medical service system should be established.

  13. Case study: Methadone maintenance treatment in Hanoi, Vietnam

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    Jardine Melissa

    2012-07-01

    Full Text Available Abstract Methadone maintenance therapy (MMT was introduced in the rapidly developing semi-rural district of Tu Liem in Hanoi in December, 2009. Commune police play an integral role in determining which injecting drug users (IDUs are eligible to commence and continue MMT. This case study highlights the importance of providing training to commune police about MMT to mitigate negative impacts drug law enforcement can have on IDU accessibility to MMT programs.

  14. The Dynamics of Urban Agriculture in Hanoi, Vietnam

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    Brody Lee

    2010-06-01

    Full Text Available In many developing countries, urban agriculture makes a significant contribution to the livelihoods of urban populations, in providing food security and income generation. In Hanoi, Vietnam’s capital city, urban agriculture is a longstanding feature, but rapid urban growth is leading to greater competition over land use, such that this practice is being increasingly threatened by conversion to non-agricultural urban uses.  The quality and safety of foodstuffs grown in urban areas is of growing concern to both consumers and producers in developing country cities such as Hanoi, where a large share of the city’s food supply is grown within the urban area. Government support has encouraged urban producers to modernize and invest in safer growing practices. However, in Hanoi, as indeed elsewhere, there is an urgent need to recognise the significance of urban agriculture in future planning strategies. Drawing upon recent field-based research in Hanoi, which examined local actors’ knowledge and perceptions of changes in urban agriculture within the city, the paper identifies key trends and underlying environmental and socio-economic factors, and considers the future sustainability of the practice.Dans de nombreux pays en voie de développement, l’agriculture urbaine représente une contribution significative à la subsistance des populations urbaines, en assurant leur sécurité alimentaire et en générant des revenus. À Hanoi, la capitale du Vietnam, l’agriculture urbaine n'est pas une nouveauté, mais la rapidité de la croissance urbaine intensifie la concurrence pour l'utilisation du sol, et la réaffectation du sol à des fins non agricoles fait peser une menace de plus en plus lourde sur cette pratique. La qualité et la sécurité des produits alimentaires cultivés dans les zones urbaines préoccupent de plus en plus les consommateurs et les producteurs dans les villes des pays en voie de développement telles que Hanoi, où une

  15. Living with autism spectrum disorder in Hanoi, Vietnam.

    Science.gov (United States)

    Ha, Vu Song; Whittaker, Andrea; Whittaker, Maxine; Rodger, Sylvia

    2014-11-01

    There is limited understanding of Autism spectrum disorder (ASD) in Vietnam. This ethnographic study aimed to explore how ASD is represented and managed in the cultural, social and economic contexts of Vietnam, and describe the experiences of families with children with ASD in Hanoi, Vietnam. This study was conducted from 2011 to 2012 in Hanoi and employed a range of methods, including participant observation, in-depth interviews with 27 parents of children with ASD and 17 key informants, and online survey. This study found that within Hanoi, Vietnam, ASD has been culturally and socially constructed as a 'disease', 'karmic demerit' and 'family problem' rather than a life-long developmental disorder that needs support from government. Children with ASD and their families experience various forms of stigma and discrimination. There are limitations in assessment and diagnosis of ASD. Parents of children with ASD have little access to services for their children, and the limited political and economic supports exacerbate their difficulties. This study highlights some of the ways in which the understandings and management of ASD vary cross culturally. It also suggests further attention is required to the provision of appropriate public education, low cost interventions and support for family advocacy groups. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Upper estimates of complexity of algorithms for multi-peg Tower of Hanoi problem

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    Sergey Novikov

    2007-06-01

    Full Text Available There are proved upper explicit estimates of complexity of lgorithms: for multi-peg Tower of Hanoi problem with the limited number of disks, for Reve's puzzle and for $5$-peg Tower of Hanoi problem with the free number of disks.

  17. Influence of corticoids on healing of the rotator cuff of rats – biomechanical study

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    Leonardo Dau

    2014-08-01

    Full Text Available Objective:To compare healing strength of the infraspinatus tendon of rats with corticoid inoculation, regarding maximum tension, maximum force and rupture force, after injury and experimental repair.Methods:A total of 60 Wistar rats were subjected to tenotomy of the infraspinatus tendon, which was then sutured. Before the surgery, they were divided into a control group (C inoculated with serum and a study group (S inoculated with corticoids over the tendon. After repair, the rats were sacrificed in groups of 10 individuals in the control group and 10 in the study group at the times of one week (C1 and S1, three weeks (C3 and S3 and five weeks (C5 and S5. The rats were dissected, separating out the infraspinatus tendon with the humerus. The study specimens were subjected to a traction test, with evaluation of the maximum tension (kgf/cm2, maximum force (kgf and rupture force (kgf, comparing the study group with the respective control groups.Results:Among the rats sacrificed one week after the procedure, we observed greater maximum tension in group C1 than in group S1. The variables of maximum force (kgf and rupture force did not differ statistically between the groups investigated. In the same way, among the rats sacrificed three weeks after the procedure, group C3 only showed greater maximum tension than group S3 (p = 0.007, and the other variables did not present differences. Among the rats sacrificed five weeks after the procedure (C5 and S5, none of the parameters studied presented statistical differences.Conclusion:We concluded that corticoid diminished the resistance to maximum tension in the groups sacrificed one and three weeks after the procedure, in comparison with the respective control groups. The other parameters did not show differences between the study and control groups.

  18. Impacts of flood on health: epidemiologic evidence from Hanoi, Vietnam

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    Debarati Guha-Sapir

    2011-08-01

    Full Text Available Vietnam is one of the most disaster-prone countries in the world. The country suffers from many kinds of natural disasters, of which the most common and serious one is flooding. Long and heavy rainfall during the last days of October and the first week of November 2008 resulted in a devastating flood unseen for over three decades in the capital city of Hanoi. It caused a substantial health impact on residents in and around the city and compromised the capacity of local health services. The aim of this study is to ascertain the vulnerability and health impacts of the devastating flood in Hanoi by identifying the differences in mortality, injuries, and morbidity patterns (dengue, pink eye, dermatitis, psychological problems, and hypertension between flood affected and non-affected households. A cross-sectional study was carried out involving 871 households in four selected communes (two heavily flood affected and two comparatively less affected from two severely flooded districts of Hanoi. Participants were interviewed and information collected on the social, economic, and health impacts of the devastation within 1 month after the flood. The self-reported number of deaths and injuries reported in this study within 1 month after the heavy rainfall were a bit higher in severely affected communes as compared to that of the less affected communes of our study. The findings showed higher incidences of dengue fever, pink eye, dermatitis, and psychological problems in communes severely affected by flood as compared to that of the controlled communes. For people in flood prone areas (at risk for flooding, flood prevention and mitigation strategies need to be seriously thought through and acted upon, as these people are exposed to greater health problems such as psychological issues and communicable diseases such as pink eye or dermatitis.

  19. Cancer in the population of Hanoi, Vietnam, 1988-1990.

    OpenAIRE

    Anh, P.T.; Parkin, D M; Hanh, N. T.; Duc, N. B.

    1993-01-01

    The first results from the population-based cancer registry for the city of Hanoi, in northern Vietnam, are presented. In men, incidence rates are moderate-low with the most common cancers being lung, stomach and liver. Cancer of the penis, reportedly very common in early case series from Vietnam, is now rarely seen. In women, incidence rates are low with the most common cancer, breast cancer, having a recorded incidence similar to that in China. Cervix cancer incidence is very low, which con...

  20. Assessment of undiscovered continuous oil and gas resources in the Hanoi Trough, Vietnam, 2017

    Science.gov (United States)

    Schenk, Christopher J.; Tennyson, Marilyn E.; Mercier, Tracey J.; Woodall, Cheryl A.; Le, Phuong A.; Klett, Timothy R.; Finn, Thomas M.; Leathers-Miller, Heidi M.; Gaswirth, Stephanie B.; Marra, Kristen R.

    2018-02-13

    Using a geology-based assessment methodology, the U.S. Geological Survey estimated mean undiscovered, technically recoverable continuous resources of 52 million barrels of oil and 591 billion cubic feet of gas in the Hanoi Trough of Vietnam.

  1. Adrenaline, terlipressin, and corticoids versus adrenaline in the treatment of experimental pediatric asphyxial cardiac arrest.

    Science.gov (United States)

    González, Rafael; Urbano, Javier; Botrán, Marta; López, Jorge; Solana, Maria J; García, Ana; Fernández, Sarah; López-Herce, Jesús

    2014-07-01

    To analyze if treatment with adrenaline (epinephrine) plus terlipressin plus corticoids achieves higher return of spontaneous circulation than adrenaline in an experimental infant animal model of asphyxial cardiac arrest. Prospective randomized animal study. Experimental department in a University Hospital. Forty-nine piglets were studied. Cardiac arrest was induced by at least 10 minutes of removal of mechanical ventilation and was followed by manual external chest compressions and mechanical ventilation. After 3 minutes of resuscitation, piglets that did not achieve return of spontaneous circulation were randomized to two groups: adrenaline 0.02 mg kg every 3 minutes (20 animals) and adrenaline 0.02 mg kg every 3 minutes plus terlipressin 20 μg kg every 6 minutes plus hydrocortisone 30 mg kg one dose (22 animals). Resuscitation was discontinued when return of spontaneous circulation was achieved or after 24 minutes. Return of spontaneous circulation was achieved in 14 piglets (28.5%), 14.2% with only cardiac massage and ventilation. Return of spontaneous circulation was achieved in 25% of piglets treated with adrenaline and in 9.1% of those treated with adrenaline plus terlipressin plus hydrocortisone (p = 0.167). Return of spontaneous circulation was achieved in 45.4% of animals with pulseless electric activity, 20% with asystole, and 0% with ventricular fibrillation (p = 0.037). Shorter duration of cardiac arrest, higher mean blood pressure and EtCO2 and lower PaCO2 before resuscitation, and higher mean blood pressure during resuscitation were associated with higher return of spontaneous circulation. Treatment with adrenaline plus terlipressin plus corticoids does not achieve higher return of spontaneous circulation than that with adrenaline in an infant animal model of asphyxial cardiac arrest.

  2. Female dominance status and fecal corticoids in a cooperative breeder with low reproductive skew: ring-tailed lemurs (Lemur catta).

    Science.gov (United States)

    Cavigelli, S A; Dubovick, T; Levash, W; Jolly, A; Pitts, A

    2003-01-01

    Many studies have shown that low dominance status within a social group is associated with elevated glucocorticoid hormone production, a common index of physiological stress. However, the reverse may be true among cooperatively breeding female mammals with high reproductive skew; that is, high dominance status is associated with elevated glucocorticoid levels. Elevated glucocorticoid levels in these dominant females may be a product of their being the only breeder within a group or may result from other challenges associated with high status. To test this difference, we studied fecal corticoid levels in cooperative breeding females with low reproductive skew (i.e., where reproduction is not limited to dominant group members): ring-tailed lemurs (Lemur catta). We collected behavioral and fecal corticoid data from 39 ring-tailed lemur females from eight groups across three sites. In seven of the eight groups, either one or both of the two most dominant females (ranks 1 and 2) exhibited the highest fecal corticoid levels in the groups. The best predictor of corticoid levels in high-ranking females was the proportion of aggressive agonistic interactions they initiated. For the lower-ranking females the best predictors of elevated corticoid levels were being the recipient of aggressive attacks and being relatively close to one's nearest neighbors. These results differ from many studies of caged male mammals where subordinate individuals often exhibit the highest glucocorticoid levels of a group. Furthermore, the results indicate that reproduction itself is not the primary reason for higher glucocorticoid levels among dominant cooperative-breeding females, but that some other factor must account for these elevated levels.

  3. ¿Afecta el tratamiento con corticoides en los periodos prenatal y posnatal el neurodesarrollo del recién nacido prematuro?

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    Marita Lardón

    2017-04-01

    Conclusión. Los resultados de este estudio no pudieron demostrar que el tratamiento perinatal con corticoides se asociara con peores resultados en el neurodesarrollo en recién nacidos de muy bajo peso.

  4. Hanoi tower-like multilayered ultrathin palladium nanosheets.

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    Yin, Xi; Liu, Xinhong; Pan, Yung-Tin; Walsh, Kathleen A; Yang, Hong

    2014-12-10

    This paper describes the synthesis, formation mechanism, and mechanical property of multilayered ultrathin Pd nanosheets. An anisotropic, Hanoi Tower-like assembly of Pd nanosheets was identified by transmission electron microscopy and atomic force microscopy (AFM). These nanosheets may contain ultrathin Pd layers, down to single unit cell thickness. Selected area electron diffraction and scanning transmission electron microscopy data show the interconnected atomically thick layers stacking vertically with rotational mismatches, resulting in unique diffractions and Moiré patterns. Density functional theory (DFT) calculation with van der Waals correction (DFT+vdW) shows the adsorption of Pd4(CO)4(OAc)4 on Pd(110) surface (Ead = -5.68 eV) is much stronger than that on Pd(100) (Ead = -4.72 eV) or on Pd(111) (Ead = -3.80 eV). The adsorption strength of this Pd complex is significantly stronger than that of CO on the same Pd surfaces. The DFT+vdW calculation results suggest a new mechanism for the observed anisotropic growth of nanosheets with unusually high aspect ratio, in which the competitive adsorptions between Pd4(CO)4(OAc)4 complex and CO on various surfaces result in a favored growth along the ⟨110⟩ directions and inhibition along ⟨111⟩ directions. The mechanical property of these multilayered Pd nanosheets was studied using AFM and nanoindentation techniques, which indicate multilayered nanosheets show more plastic deformation than the bulk in response to an applied force.

  5. Prediction maps of land subsidence caused by groundwater exploitation in Hanoi, Vietnam

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    Thinh Hong Phi

    2015-12-01

    Full Text Available The article presents study results of the land subsidence caused by groundwater exploitation in Hanoi, Vietnam. The study includes collection and analysis of data on geology, hydrology, soil properties and settlements observed at 10 monitoring stations as well as models of the time-dependent settlement. The calculated settlements are relatively close to actual monitoring data. The models were done for prediction of the land subsidence at 92 selected points by the finite element method. Prediction maps are made for prediction of the land subsidence in 2020 and 2030. Recommendations are proposed for potential zones of groundwater exploitation in Hanoi.

  6. Alcohol-related harm among university students in Hanoi, Vietnam

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    Pham Bich Diep

    2013-02-01

    Full Text Available Introduction and Aim: This study examines the prevalence of and risk factors for alcohol-related harm and types of harm among medical students from Hanoi Medical University (Vietnam. Risk factors include aspects of drinking patterns and relevant socio-demographic variables. Study Design and Methods: A cross-sectional study involving 1st to 6th year students (N=1216; response rate 96.5%. Of these, 210 students from each academic year were randomly selected from a sampling frame covering all students from each academic year. Data were collected using a questionnaire distributed in class by researchers. Drinkers completed 23 questions on alcohol-related harm categorized into: 1 ‘negative influence on daily activities’; 2 ‘social conflict’; 3 ‘loss of control, acute consequences, and withdrawal’; 4 ‘mental health conditions’; and 5 ‘physical and medical health problems’. Logistic and Poisson regression models were used to identify the predictors of alcohol-related harm and the amount of harm, respectively. Results: The prevalence of alcohol use associated with at least one or more of the five types of harm was higher in men (81.8% than in women (60.4%. In female and male students, the most common harm category was ‘loss of control, acute consequences, and withdrawal’ (51.8 and 75.6%, respectively, followed by ‘negative influence on daily activities’ (29.4 and 55.8%, respectively. Age, living away from home, and average number of standard drinks per occasion among male drinkers, and age and frequency of drinking per week among female drinkers were associated with alcohol-related harm. Conclusions: These data suggest that alcohol-related harm represents a serious public health problem among young educated individuals in Vietnam. The risk factors indicate that prevention should be aimed at aspects of drinking patterns and specific subpopulations defined by gender, age, and (for men only type of living situation.

  7. Excellent Teacher Training at University of Education, Vietnam National University Hanoi.

    OpenAIRE

    Nguyen Thi My Loc,

    2011-01-01

    This paper discusses the importance of excellent teachers, factors which impact on the quality of teacher training in general, teacher training in Vietnam and the model of excellent teacher training at the University of Education, Vietnam National University in Hanoi in particular.

  8. Quantifying the Emergence of Dengue in Hanoi, Vietnam: 1998-2009

    NARCIS (Netherlands)

    Cuong, H.Q.; Hien, N.T.; Duong, T.N.; Phong, T.V.; Cam, N.N.; Farrar, J.; Nam, V.S.; Thai, K.T.D.; Horby, P.

    2011-01-01

    Background: An estimated 2.4 billion people live in areas at risk of dengue transmission, therefore the factors determining the establishment of endemic dengue in areas where transmission suitability is marginal is of considerable importance. Hanoi, Vietnam is such an area, and following a large

  9. Availability and accessibility of HIV counseling and testing services for pregnant women in Hanoi, Vietnam

    NARCIS (Netherlands)

    Nguyen, T.A.; Oosterhoff, P.; Hardon, A.; Ngoc, Y.P.; Tran, H.N.; Coutinho, R.A.; Wright, P.

    2009-01-01

    In Hanoi, Vietnam, HIV counseling and testing is available but apparently still many HIV-positive women were either not detected or were identified too late for optimal PMTCT intervention. The study looked at how easily pregnant women could find out about and use HIV counseling and testing and

  10. Institutional aspects of integrating irrigation into urban wastewater management: the case of Hanoi, Vietnam

    NARCIS (Netherlands)

    Evers, J.G.; Huibers, Frans P.; van Vliet, Bas J.M.

    2008-01-01

    Wastewater flows of metropolitan cities and their downstream use for irrigation are often associated with technical systems. However, an engineering approach on its own will leave questions unanswered at the socio-technical and institutional level. Research was carried out in Hanoi, Vietnam, on the

  11. Institutional aspects of integrating irrigation into urban wastewater management: the case of Hanoi, Vietnam

    NARCIS (Netherlands)

    Evers, J.G.; Huibers, F.P.; Vliet, van B.J.M.

    2010-01-01

    Wastewater flows of metropolitan cities and their downstream use for irrigation are often associated with technical systems. However, an engineering approach on its own will leave questions unanswered at the socio-technical and institutional level. Research was carried out in Hanoi, Vietnam, on the

  12. Using the Tower of Hanoi Puzzle to Infuse Your Mathematics Classroom with Computer Science Concepts

    Science.gov (United States)

    Marzocchi, Alison S.

    2016-01-01

    This article suggests that logic puzzles, such as the well-known Tower of Hanoi puzzle, can be used to introduce computer science concepts to mathematics students of all ages. Mathematics teachers introduce their students to computer science concepts that are enacted spontaneously and subconsciously throughout the solution to the Tower of Hanoi…

  13. Dietary exposure to essential and potentially toxic elements for the population of Hanoi, Vietnam.

    Science.gov (United States)

    Marcussen, Helle; Jensen, Bodil H; Petersen, Annette; Holm, Peter E

    2013-01-01

    Knowledge of the dietary intake of essential and toxic elements in fast-developing Southeast Asian countries such as Vietnam is limited. Iron and Zn deficiency in Asia is a well-known problem and is partly due to rice constituting a major part of the diet. Dietary habits are changing and there is a need to build more knowledge so authorities can give dietary recommendations. The aim of this study was to determine the total dietary intake of essential and potentially toxic elements and to assess the nutritional quality and food safety risks of the average Hanoi diet. Twenty-two foods or food groups were identified and 14 samples of each food group were collected from markets and/or supermarkets in the period 2007-2009. Water spinach, water dropwort, watercress, water mimosa and pond fish are typically produced in wastewater-fed systems. Therefore, these samples were collected both at markets and from wastewater-fed production systems. The results showed little or no risk of toxic elements from the Hanoi diet in general. Further, element contributions from wastewater-fed products were low and does not seem to constitute a problem with respect to potentially toxic elements. A comparison of the average Hanoi dietary intake of essential elements to required intakes shows that the Hanoi diet is sufficient in most elements. However, the diet may be insufficient in Ca, Cr, Fe, K and possibly Zn for which dietary diversification of biofortification might provide solutions.

  14. Corticoides transforaminales en la radiculopatía lumbosacra: valoración del dolor y la discapacidad

    OpenAIRE

    P. Papa de la Rosa

    2014-01-01

    Objetivo: el objetivo del trabajo fue determinar la efectividad clínica de una inyección epidural transforaminal de corticoides en una población de pacientes con lumbociatalgia por compresión radicular y escasa respuesta al tratamiento previo. Teniendo en cuenta que el dolor es un síntoma multidimensional cuya expresión final dependerá de factores afectivos, cognitivos, emocionales, y socio-culturales, la evaluación de la eficacia del tratamiento se realizó por medio de la forma abreviada del...

  15. Prefrontal EEG correlation during Tower of Hanoi and WCST performance: effect of emotional visual stimuli.

    Science.gov (United States)

    Ruiz-Díaz, Marina; Hernández-González, Marisela; Guevara, Miguel Angel; Amezcua, Claudia; Ågmo, Anders

    2012-10-01

    Emotional stimuli elicit changes in the electroencephalographic (EEG) activity of several brain structures. Prefrontal cortex is involved in the processing of emotional stimuli and executive functions. The correlation analysis of EEG provides information about the functional coupling between areas. It is reasonable to expect that emotional activation will modify prefrontal coupling during the performance of executive tasks such as Tower of Hanoi or Wisconsin Card Sorting Test (WCST). Determine whether the prefrontal EEG correlation during the performance of the Tower of Hanoi and WCST is affected by previous exposure to videos with sexual or aggressive content. Prefrontal EEG coupling was determined by the Pearson correlation. Valence and general arousal were evaluated by the Self-Assessment Manikin Scale and sexual arousal with a Sexual Arousal Scale. Computerized versions of the Towers of Hanoi and WCST provided data on prefrontal executive functions. EEG from the left and right prefrontal zones was recorded during the performance of the Tower of Hanoi and WCST immediately after the subjects were exposed to one of the videos (neutral, aggressive, and erotic). There was no difference between videos in the task performance parameters. Only the erotic video produced an increased prefrontal coupling in the slow bands (delta and theta) during the performance of the Tower of Hanoi, whereas a decreased coupling in the delta, theta, and alpha bands was observed during the WCST. Prefrontal coupling was changed after exposure to the erotic video, and it is likely that enhanced sexual arousal was the main cause of this change. The correlation patterns obtained could be associated with particular cognitive strategies or to functional adaptations while being sexually aroused. The results of this study may contribute to an understanding of the central nervous mechanisms underlying the cognitive effects of sexual arousal. © 2012 International Society for Sexual Medicine.

  16. Influence of veterinary care on the urinary corticoid:creatinine ratio in dogs.

    Science.gov (United States)

    van Vonderen, I K; Kooistra, H S; Rijnberk, A

    1998-01-01

    Physical and emotional stresses are known to increase the production and secretion of glucocorticoids by the adrenal cortex in both humans and experimental animals. The urinary corticoid: creatinine (C:C) ratio is increasingly used as a measure of adrenocortical function. In this study we investigated whether a visit to a veterinary practice for vaccination, a visit to a referral clinic for orthopedic examination, or hospitalization in a referral clinic for 1.5 days resulted in increases of the urinary C:C ratio in pet dogs. In experiment 1, owners collected voided urine samples from 19 healthy pet dogs at specified times before and after taking the dogs to a veterinary practice for yearly vaccination. In experiment 2, 12 pet dogs were evaluated in a similar way before and after an orthopedic examination at a referral clinic. In experiment 3, 9 healthy pet dogs were hospitalized for 1.5 days and urine samples were collected before, during, and after this stay. Basal urinary C:C ratios in all experiments ranged from 0.8 to 8.3 x 10(-6). In experiment 1, the urinary C:C ratio after the visit to the veterinary practice ranged from 0.9 to 22.0 x 10(-6). Six dogs had a significantly increased urinary C:C ratio (responders), but in 5 of these dogs the ratio was dogs responded significantly with urinary C:C ratios ranging from 3.1 to 27.0 x 10(-6). In experiment 3, 8 of 9 dogs had significantly increased urinary C:C ratios, ranging from 2.4 to 24.0 x 10(-6), in some or all urine samples collected during hospitalization. In 4 dogs urinary C:C ratios 12 hours after hospitalization were still significantly higher than the initial values. Thus, a visit to a veterinary practice, an orthopedic examination in a referral clinic, and hospitalization can be considered stressful conditions for dogs. A large variation occurs in response, and in individual dogs the increases in urinary C:C ratios can exceed the cutoff level for the diagnosis of hyperadrenocorticism. Therefore, urine

  17. Construction of Urban 3-D Model of Hanoi, Vietnam Using FOSS Tools

    Science.gov (United States)

    Yonezawa, G.; Mitamura, M.; Sakurai, K.; Luan, T. X.; Raghavan, V.; Masumoto, S.; Nemoto, T.; Nonogaki, S.

    2013-12-01

    In this study, we investigate an urban transformation of Hanoi City, Vietnam from topographic changes in the 19-20 centuries. To analyze the relief of terrain and micro-topography for such an urban transfiguration, we need to generate the DEM (Digital Elevation Model) using the elevation survey data. DEM is a digital representation of ground surface topography and the most important element of topographic analysis for urban transfiguration. And, the three dimensional (3-D) mode of buildings which we generated from house map in Hanoi City can be also expressed apparently. It must be useful for an urban transformation because it is difficult to estimate how so many lakes and ponds disappeared by using two dimensional (2-D) spatial analysis only. We generated the DEM (8km x 8km) of Hanoi City from approximately 24,000 points data collected in 2005. This survey data was provided by Hanoi University of Mining and Geology (HUMG). Based on the surface estimation method using Cubic B-Spline Function, we generated this DEM at 2 meters resolution (Nonogaki et al., 2008). The very subtle elevation gaps which can not be distinguished on the satellite image are significantly recognizable on it. The example of the visualization of 3-D DEM is shown in Figure 1 using the NVIZ of visualization tool in GRASS GIS software. It is overlaid the Hanoi road map on the generated DEM. We generated the vector map of each block of houses in the Pho Co district in Hanoi City by using the house maps in 2005 which are provided by HUMG. It is consisted of 12,000 polygon data. These are converted the 3-D data (features) using the GIS software. This 3-D model is not only visualized the landscape in the Pho Co district accurately, but also reflected the elevation in this area. Thus, the 3-D features are built on DEM which is shown in Chapter 3. Therefore, we can create an overview of how the current urbanization is advancing in the area where the lakes and ponds existed in the past. Example of the

  18. Dietary exposure to essential and potentially toxic elements for the population of Hanoi, Vietnam

    DEFF Research Database (Denmark)

    Marcussen, H.; Jensen, Bodil Hamborg; Petersen, Annette

    2013-01-01

    and there is a need to build more knowledge so that authorities can give dietary recommendations. The aim of this study was to determine the total dietary intake of essential and potentially toxic elements and to assess the nutritional quality and food safety risks of the average Hanoi diet. 22 foods or food groups...... were identified and 14 samples of each food group were collected from markets and/or supermarkets in the period 2007-2009. Water spinach, water dropwort, watercress, water mimosa and pond fish are typically produced in wastewater-fed systems. Therefore, these samples were collected both at markets...... and from wastewater-fed production systems. The results showed little or no risk of toxic elements from the Hanoi diet in general. Further, element contributions from wastewater-fed products were low and does not seem to constitute a problem with respect to potentially toxic elements. A comparison...

  19. Elemental composition of tropospheric aerosols in Hanoi, Vietnam and Nairobi, Kenya

    Energy Technology Data Exchange (ETDEWEB)

    Gatari, M.; Wagner, A.; Boman, J. [Department of Chemistry, Atmospheric Science, Goeteborg University, SE-412 96 Goeteborg (Sweden)

    2005-04-01

    Air pollution problems in major cities within the developing countries need to be studied. There are scanty measurements from the developing countries on airborne particles despite their adverse implications to human health, visibility and climate. One of the major sources of anthropogenic air pollution is energy production. Energy demand is bound to increase as population increases, especially in major cities of the world. Fine particles, particles with aerodynamic diameter {<=}2.5 {mu}m, are mainly anthropogenic and these particles were collected in the capital cities of Vietnam and Kenya. A cyclone airborne particle collector was used to sample in Hanoi during the months of May to October 2000 and a dichotomous virtual impactor in Nairobi in February 2000. The samples were analysed for elemental content by an energy dispersive X-ray fluorescence (EDXRF) spectrometer. S, Cl, K and Fe exceeded atmospheric concentrations of 100 ng m{sup -3} at both cities. Atmospheric elemental concentrations in both Hanoi and Nairobi were orders of magnitude higher than their respective rural towns. Traffic, biomass and waste burning emissions were implicated as the main sources of air pollution in Nairobi, while coal combustion and road transport were the major sources in Hanoi. Regional air pollution had a major impact over Hanoi, whereas an influence of that kind was not identified in Nairobi. Pb and other toxic elements had concentration levels below WHO guideline, however, the two cities are threatened by future high levels of air pollution due to the high rate of population growth. Long-term measurements are required in both areas to evaluate if the alarming situation is deteriorating.

  20. Willingness to Pay for Organic Vegetables in Vietnam : An Empirical Analysis in Hanoi capital

    OpenAIRE

    Hai, Ngo Minh; Moritaka, Masahiro; Fukuda, Susumu

    2013-01-01

    High levels of pesticide and chemical fertilizer inside vegetables are always risky to Vietnamese people in general, Hanoi’s people in particular when only about 30% of the area for vegetable production in Hanoi are controlled and safely certified by the government. The consumers still become worried, even some of them do not totally trust the safe vegetables because the chemical residue, pesticide levels are difficult to fully check and control due to insufficient capability of the state’s a...

  1. Epidemiology of dengue fever in Hanoi from 2002 to 2010 and its meteorological determinants

    Directory of Open Access Journals (Sweden)

    Dao Thi Minh An

    2014-12-01

    Full Text Available Background: Dengue fever (DF is a growing public health problem in Vietnam. The disease burden in Vietnam has been increasing for decades. In Hanoi, in contrast to many other regions, extrinsic drivers such as weather have not been proved to be predictive of disease frequency, which limits the usefulness of such factors in an early warning system. Aims: The purpose of this research was to review the epidemiology of DF transmission and investigate the role of weather factors contributing to occurrence of DF cases. Methods: Monthly data from Hanoi (2002–2010 were used to test the proposed model. Descriptive time-series analysis was conducted. Stepwise multivariate linear regression analysis assuming a negative binomial distribution was established through several models. The predictors used were lags of 1–3 months previous observations of mean rainfall, mean temperature, DF cases, and their interactions. Results: Descriptive analysis showed that DF occurred annually and seasonally with an increasing time trend in Hanoi. The annual low occurred from December to March followed by a gradual increase from April to July with a peak in September, October. The amplitude of the annual peak varied between years. Statistically significant relationships were estimated at lag 1–3 with rainfall, autocorrelation, and their interaction while temperature was estimated as influential at lag 3 only. For these relationships, the final model determined a correlation of 92% between predicted number of dengue cases and the observed dengue disease frequencies. Conclusions: Although the model performance was good, the findings suggest that other forces related to urbanization, density of population, globalization with increasing transport of people and goods, herd immunity, government vector control capacity, and changes in serotypes are also likely influencing the transmission of DF. Additional research taking into account all of these factors besides climatic

  2. Pollution and potential mobility of Cd, Ni and Pb in the sediments of a wastewater-receiving river in Hanoi, Vietnam

    DEFF Research Database (Denmark)

    Ingvertsen, Simon T.; Marcussen, Helle; Holm, Peter E.

    2013-01-01

    Large quantities of untreated industrial and domestic wastewater are discharged from the city of Hanoi into urban rivers. Sediment samples from three sites in the To Lich River in Hanoi were assessed with respect to the concentrations and potential mobility of cadmium (Cd), nickel (Ni) and lead (Pb...

  3. Transfer method of conducting in the symphony orchestra of the Hanoi National Conservatory of Music, Vietnam

    Directory of Open Access Journals (Sweden)

    Parichat Wiang-in

    2015-11-01

    Full Text Available This is a qualitative designed and conducted with two primary research aims, which were: 1 To study the life and experiences of symphonic orchestra conductors in Hanoi, Vietnam; 2 To study the inheritance process for conductors of the symphonic orchestra in Hanoi, Vietnam. The research area for this investigation was purposively selected as the Vietnam National Academy of Music in Hanoi. The investigation began in October 2012 and was concluded in January 2014. The two key informants for this investigation were expert conductors and teachers at the academy, Dr. Nguyễn Phúc Linh and Dr. Nguyễn Thiếu Hoa. Data was collected from a combination of document analysis and field research. Tools used for data collection included interviews, participant and non-participant observation and focus group discussions. Results show that both of the key informants for this investigation were born into families of artists and had a particularly close relationship with traditional folk art. Scholarships to study abroad at the Tchaikovsky University, Russia enabled them to learn from Russian conductors and they developed the skills that have now led them to be recognized as being among the most accomplished conductors in Vietnam. The process of instruction preferred by these two academics is taught in three steps: the preparation stage, the teaching stage and the assessment and evaluation stage. The benefits of studying with Dr. Nguyễn Phúc Linh and Dr. Nguyễn Thiếu Hoa are the cumulative experiences of international conducting practices and the high standards that the two academics possess and demand.

  4. The impact of 4Ps on Purchase Decision: A case of Apple in Hanoi, Vietnam

    Directory of Open Access Journals (Sweden)

    Bui Trung Thieu

    2016-01-01

    Full Text Available By using quantitative research methods and deductive reasoning, this research paper aims to address the importance of four marketing mix components (4Ps on purchase decisions of customers of Apple Inc., by launching a survey in Hanoi, Vietnam, to generate primary data. The chosen sampling technique is quota sampling and several “quotas” were built. Descriptive analysis and hypothetical analysis (t-test, one-way ANOVA and Regression using SPSS 20.0 are applied. Other implications of the research and limitations were also discussed below.

  5. Diarrhea Caused by Rotavirus in Children Less than 5 Years of Age in Hanoi, Vietnam

    OpenAIRE

    Nguyen, Trung Vu; Le, Phung Van; Le Huy, Chinh; Weintraub, Andrej

    2004-01-01

    Group A rotaviruses are the major cause of diarrhea in young children worldwide. From March 2001 to April 2002, 836 children less than 5 years of age were investigated in Hanoi, Vietnam. This included 587 children with diarrhea and 249 age-matched controls. Group A rotavirus was identified in 46.7% of the children with diarrhea and 3.6% of the controls, which was a significant difference. Within the diarrhea group, the highest prevalence was seen in children from 13 to 24 months of age, and t...

  6. Contact investigation in households of patients with tuberculosis in Hanoi, Vietnam: a prospective cohort study.

    Directory of Open Access Journals (Sweden)

    Gregory James Fox

    Full Text Available SETTING: Existing tuberculosis control strategies in Vietnam are based on symptomatic patients attending health services for investigation. This approach has not resulted in substantial reductions in the prevalence of tuberculosis disease, despite the National Tuberculosis Program achieving high treatment completion rates. Alternative approaches are being considered. OBJECTIVE: To determine the feasibility and yield of contact investigation in households of patients with smear positive pulmonary tuberculosis among household members of tuberculosis patients in Hanoi, Vietnam. METHODS: Household contacts of patients with smear positive pulmonary tuberculosis were recruited at four urban and rural District Tuberculosis Units in Hanoi. Clinical and radiological screening was conducted at baseline, six months and 12 months. Sputum microscopy and culture was performed in contacts suspected of having tuberculosis. MIRU-VNTR molecular testing was used to compare the strains of patients and their contacts with disease. RESULTS: Among 545 household contacts of 212 patients, four were diagnosed with tuberculosis at baseline (prevalence 734 cases per 100,000 persons, 95% CI 17-1451 and one was diagnosed with tuberculosis during the subsequent 12 months after initial screening (incidence 180 cases per 100,000 person-years, 95% CI 44-131. Two of these cases were culture positive for M. tuberculosis and both had identical or near-identical MIRU-VNTR strain types. CONCLUSION: Household contacts of patients with potentially infectious forms of tuberculosis have a high prevalence of disease. Household contact investigation is feasible in Vietnam. Further research is required to investigate its effectiveness.

  7. Content, distribution and fate of 33 elements in sediments of rivers receiving wastewater in Hanoi, Vietnam

    Energy Technology Data Exchange (ETDEWEB)

    Marcussen, Helle [Department of Natural Sciences, Faculty of Life Sciences, University of Copenhagen, Thorvaldsensvej 40, 1871 Frederiksberg C (Denmark); Department of Veterinary Pathobiology, Faculty of Life Sciences, University of Copenhagen, Stigboejlen 4, 1870 Frederiksberg C (Denmark)], E-mail: hma@life.ku.dk; Dalsgaard, Anders [Department of Veterinary Pathobiology, Faculty of Life Sciences, University of Copenhagen, Stigboejlen 4, 1870 Frederiksberg C (Denmark); Holm, Peter E. [Department of Natural Sciences, Faculty of Life Sciences, University of Copenhagen, Thorvaldsensvej 40, 1871 Frederiksberg C (Denmark)

    2008-09-15

    Untreated industrial and domestic wastewater from Hanoi city is discharged into rivers that supply water for various agricultural and aquacultural food production systems. The aim of this study was to assess the content, distribution and fate of 33 elements in the sediment and pore water of the main wastewater receiving rivers. The sediment was polluted with potentially toxic elements (PTEs) with maximum concentrations of 73 As, 427 Cd, 281 Cr, 240 Cu, 218 Ni, 363 Pb, 12.5 Sb and 1240 Zn mg kg{sup -1} d.w. Observed distribution coefficients (log{sub 10} K{sub d,obs}) were calculated as the ratio between sediment (mg kg{sup -1} d.w.) and pore water (mg L{sup -1}) concentrations. Maxima log{sub 10} K{sub d,obs} were >4.26 Cd, >6.60 Cu, 4.78 Ni, 7.01 Pb and 6.62 Zn. The high values show a strong PTE retention and indicate the importance of both sorption and precipitation as retention mechanisms. Sulphide precipitation was a likely mechanism due to highly reduced conditions. - Sorption and precipitation processes are important in retention of potentially toxic elements in Hanoi river sediment and prevent elements entering food production systems.

  8. Holocene estuarine sediments as a source of arsenic in Pleistocene groundwater in suburbs of Hanoi, Vietnam

    Science.gov (United States)

    Kuroda, Keisuke; Hayashi, Takeshi; Funabiki, Ayako; Do, An Thuan; Canh, Vu Duc; Nga, Tran Thi Viet; Takizawa, Satoshi

    2017-06-01

    Groundwater pollution by arsenic is a major health threat in suburban areas of Hanoi, Vietnam. The present study evaluates the effect of the sedimentary environments of the Pleistocene and Holocene deposits, and the recharge systems, on the groundwater arsenic pollution in Hanoi suburbs distant from the Red River. At two study sites (Linh Dam and Tai Mo communes), undisturbed soil cores identified a Pleistocene confined aquifer (PCA) and Holocene unconfined aquifer (HUA) as major aquifers, and Holocene estuarine and deltaic sediments as an aquitard layer between the two aquifers. The Holocene estuarine sediments (approximately 25-40 m depth, 9.6-4.8 cal ka BP) contained notably high concentrations of arsenic and organic matter, both likely to have been accumulated by mangroves during the Holocene sea-level highstand. The pore waters in these particular sediments exhibited elevated levels of arsenic and dissolved organic carbon. Arsenic in groundwater was higher in the PCA (25-94 μg/L) than in the HUA (5.2-42 μg/L), in both the monitoring wells and neighboring household tubewells. Elevated arsenic concentration in the PCA groundwater was likely due to vertical infiltration through the arsenic-rich and organic-matter-rich overlying Holocene estuarine sediments, caused by massive groundwater abstraction from the PCA. Countermeasures to prevent arsenic pollution of the PCA groundwater may include seeking alternative water resources, reducing water consumption, and/or appropriate choice of aquifers for groundwater supply.

  9. Urbanisation and sexual health: understanding bisexually active men in Hanoi, Vietnam.

    Science.gov (United States)

    Higgs, Peter; Reddel, Siobhan; Pham, Hanh Van; Dang, Khoat Van; Hellard, Margaret

    2014-01-01

    Background : Men who have sex with men (MSM) in Vietnam are receiving increased attention in recognition of their high-risk behaviours and potential for human immunodeficiency virus (HIV) infection and transmission. Due to societal pressures, many MSM in Vietnam are also bisexually active, which ultimately increases the transmission risks beyond the MSM population. Evidence is emerging that indicates a greater proportion of women in Asia with low-risk sexual activities are contracting HIV from their male partners who have become HIV infected through male-male sex. Methodology : Fourteen focus group discussions exploring sexual and social networks were conducted in Hanoi between July 2010 and September 2010. A total of 96 individuals participated in these sessions. Findings : A risk environment approach was used to analyse the focus group themes of social stigma and marriage, sex with other men in closed settings and transactional sex in Hanoi, an increasingly urbanising and westernising city. Implications : Despite limited evidence globally that bisexual men act as a bridge for sexually transmitted diseases, there is particular concern in Vietnam about this potential risk. HIV rates amongst MSM are rapidly rising and there are reports of women contracting HIV from their male partners who are bisexually active.

  10. Nutrient management and institutional cooperation as conditions for environmentally safe wastewater irrigation: the case of Hanoi, Vietnam

    NARCIS (Netherlands)

    Evers, J.G.; Huibers, F.P.; van Vliet, Bas J.M.; Dung, N.V.; Van, D.T.H.; Ragab, Ragab; Koo-Oshima, Sasha

    2006-01-01

    Hanoi is rapidly growing in population and in economic activities. Increasing volumes of domestic and industrial wastewater flows are discharged mostly untreated into the drainage system. At downstream level, these polluted, nutrient rich waters are used for irrigation. Nutrient concentrations in

  11. Surveillance of congenital rubella syndrome (CRS) in tertiary care hospitals in Hanoi, Vietnam during a rubella epidemic.

    Science.gov (United States)

    Van Bang, Nguyen; Van Anh, Nguyen Thi; Van, Vu Thi Tuong; Thai, Trieu Thi Hong; Van Thuong, Nguyen; Khandaker, Gulam; Elliott, Elizabeth

    2014-12-12

    To describe the epidemiology and clinical features of congenital rubella syndrome (CRS) in Hanoi, Vietnam. Prospective surveillance of CRS between May 2011 and March 2012 in Hanoi, Vietnam. CRS burden was assessed by clinical examination and collection of serum samples from infants in neonatology, cardiology and pediatric departments of two tertiary care hospitals in Hanoi. All infants born during the study period with clinical manifestations of CRS and seropositivity (IgM) for rubella were included in this study. During the surveillance period 113 infants were identified with confirmed CRS (clinical features and positive rubella IgM). Their mean age at diagnosis was 38.4 days (range 1-152 days) and 61% were female. Clinical manifestations of CRS included low birth weightrubella vaccine in the past and 88.4% gave a history of rubella contact during the pregnancy under study. In most cases (84.1%) maternal infection occurred in the first trimester. During the surveillance period the estimated annual incidence of CRS was 1.13/1000 live births (95% CI 0.92-1.34). These preliminary baseline data show a high burden of CRS in Hanoi, Vietnam and the urgent need for universal vaccination. Surveillance to determine and monitor the national burden of CRS is essential. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Influence of urbanity on perception of mental illness stigma: a population based study in urban and rural Hanoi, Vietnam.

    Science.gov (United States)

    Ta, Thi Minh Tam; Zieger, Aron; Schomerus, Georg; Cao, Tien Duc; Dettling, Michael; Do, Xuan Tinh; Mungee, Aditya; Diefenbacher, Albert; Angermeyer, Matthias C; Hahn, Eric

    2016-12-01

    To examine, for the first time in Vietnam, whether urbanity of respondents among other socio-demographic factors affects the public perception of stigma attached to persons with mental illness in Hanoi. A general population-based survey was carried out in 2013 in the greater Hanoi area. The perception of stigma attached to people with mental illness was elicited using Link's perceived discrimination and devaluation scale (PDDS) carried out in Vietnamese language. The survey sample (n = 806) was stratified for gender, urban/rural location, age, household size and marital status, in accordance with the 2013 Vietnamese census. Comparing the total score of the PDDS and its single items, we found less perceived stigma and discrimination among the rural population of Hanoi and in respondents who reported religious attainment to either Buddhism or Christianity. Logistic regression analyses found no significant influences of gender, age, household size or marital status regarding the perceived stigma toward persons with mental illness. Less negative perception of stigma attached to persons with mental illness that was observed among the rural population in the Hanoi area may be interpreted in the light of possibly more demanding living conditions in modern urban Vietnam with less opportunities for mentally ill patients and points toward a dynamic interaction with rapidly changing living conditions in Asian megacities. © The Author(s) 2016.

  13. Social marketing of low dead space syringes in Vietnam: findings from a 1-year pilot program in Hanoi, Thai Nguyen, and Ho Chi Minh City

    National Research Council Canada - National Science Library

    Huong, Ngo Thi Thanh; Mundy, Gary; Neukom, Josselyn; Zule, William; Tuan, Nguyen Minh; Tam, Nguyen Minh

    2015-01-01

    ...) to shift from high to low dead space syringes. Using a mix of consumer and trade marketing approaches, informed by rapid assessments of both the syringe market and PWID preferences, practices, and behaviors in Hanoi and Ho Chi Minh City...

  14. Hot spot detection and spatio-temporal dispersion of dengue fever in Hanoi, Vietnam. (Special Issue: Public health in Vietnam: here's the data, where's the action?)

    NARCIS (Netherlands)

    Do Thi Thanh, Toan; Hu, WenBiao; Pham Quang, Thai; Luu Ngoc, Hoat; Wright, P; Martens, P

    2013-01-01

    Introduction: Dengue fever (DF) in Vietnam remains a serious emerging arboviral disease, which generates significant concerns among international health authorities. Incidence rates of DF have increased significantly during the last few years in many provinces and cities, especially Hanoi. The

  15. Roles of surface water areas for water and solute cycle in Hanoi city, Viet Nam

    Science.gov (United States)

    Hayashi, Takeshi; Kuroda, Keisuke; Do Thuan, An; Tran Thi Viet, Nga; Takizawa, Satoshi

    2013-04-01

    Hanoi city, the capital of Viet Nam, has developed beside the Red river. Recent rapid urbanization of this city has reduced a large number of natural water areas such as lakes, ponds and canals not only in the central area but the suburban area. Contrary, the urbanization has increased artificial water areas such as pond for fish cultivation and landscaping. On the other hand, the urbanization has induced the inflow of waste water from households and various kinds of factories to these water areas because of delay of sewerage system development. Inflow of the waste water has induced eutrophication and pollution of these water areas. Also, there is a possibility of groundwater pollution by infiltration of polluted surface water. However, the role of these water areas for water cycle and solute transport is not clarified. Therefore, this study focuses on the interaction between surface water areas and groundwater in Hanoi city to evaluate appropriate land development and groundwater resource management. We are carrying out three approaches: a) understanding of geochemical characteristics of surface water and groundwater, b) monitoring of water levels of pond and groundwater, c) sampling of soil and pond sediment. Correlation between d18O and dD of precipitation (after GNIP), the Red River (after GNIR) and the water samples of this study showed that the groundwater is composed of precipitation, the Red River and surface water that has evaporation process. Contribution of the surface water with evaporation process was widely found in the study area. As for groundwater monitoring, the Holocene aquifers at two sites were in unconfined condition in dry season and the groundwater levels in the aquifer continued to increase through rainy season. The results of isotopic analysis and groundwater level monitoring showed that the surface water areas are one of the major groundwater sources. On the other hand, concentrations of dissolved Arsenic (filtered by 0.45um) in the pore

  16. Second-trimester abortions and sex-selection of children in Hanoi, Vietnam.

    Science.gov (United States)

    Bélanger, Danièle; Oanh, Khuat Thi Hai

    2009-07-01

    Because sex-selective abortions are generally conducted during the second term of the pregnancy, timing of abortion can be used as an indirect way of studying sex-selection by abortion. We examined the likelihood of having a first-trimester vs. second-trimester abortion among a group of 885 married women who had an abortion in an obstetric hospital in Hanoi in 2003. In the absence of sex-selection by abortion, the number and sex of living children should not affect the timing of abortion. Results indicate that women with more children, particularly those with more daughters or without a son, were more likely to undergo a second-term abortion than a first-term abortion. We estimate that, in 2003, 2 per cent of all abortions to women with at least one living child were intended to avoid the birth of a female.

  17. Seasonality in mortality and its relationship to temperature among the older population in Hanoi, Vietnam

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    Le Thi Thanh Xuan

    2014-12-01

    Full Text Available Background: Several studies have established a relationship between temperature and mortality. In particular, older populations have been shown to be vulnerable to temperature effects. However, little information exists on the temperature–mortality relationship in Vietnam. Objectives: This article aims to examine the monthly temperature–mortality relationship among older people in Hanoi, Vietnam, over the period between 2005 and 2010, and estimate seasonal patterns in mortality. Methods: We employed Generalized Additive Models, including smooth functions, to model the temperature–mortality relationships. A quasi-Poisson distribution was used to model overdispersion of death counts. Temporal trends, seasonality, and population size were adjusted for while estimating changes in monthly mortality over the study period. A cold month was defined as a month with a mean temperature below 19°C. Results: This study found that the high peak of mortality coincided with low temperatures in the month of February 2008, during which the mean temperature was the lowest in the whole study period. There was a significant relationship between mean monthly temperature and mortality among the older people (p<0.01. Overall, there was a significant decrease in the number of deaths in the year 2009 during the study period. There was a 21% increase in the number of deaths during the cold season compared to the warm season. The increase in mortality during the cold period was higher among females compared to males (female: IRR [incidence relative risk] =1.23; male: IRR=1.18. Conclusions: Cold temperatures substantially increased mortality among the older population in Hanoi, Vietnam, and there were gender differences. Necessary preventive measures are required to mitigate temperature effects with greater attention to vulnerable groups.

  18. Occurrence, fate and antibiotic resistance of fluoroquinolone antibacterials in hospital wastewaters in Hanoi, Vietnam.

    Science.gov (United States)

    Duong, Hong Anh; Pham, Ngoc Ha; Nguyen, Hoang Tung; Hoang, Thi Thuong; Pham, Hung Viet; Pham, Van Ca; Berg, Michael; Giger, Walter; Alder, Alfredo C

    2008-06-01

    Occurrence and behavior of fluoroquinolone antibacterial agents (FQs) were investigated in hospital wastewaters in Hanoi, Vietnam. Hospital wastewater in Hanoi is usually not treated and this untreated wastewater is directly discharged into one of the wastewater channels of the city and eventually reaches the ambient aquatic environment. The concentrations of the FQs, ciprofloxacin (CIP) and norfloxacin (NOR) in six hospital wastewaters ranged from 1.1 to 44 and from 0.9 to 17 micrgl(-1), respectively. Total FQ loads to the city sewage system varied from 0.3 to 14 g d(-1). Additionally, the mass flows of CIP and NOR were investigated in the aqueous compartment in a small wastewater treatment facility of one hospital. The results showed that the FQ removal from the wastewater stream was between 80 and 85%, probably due to sorption on sewage sludge. Simultaneously, the numbers of Escherichia coli (E. coli) were measured and their resistance against CIP and NOR was evaluated by determining the minimum inhibitory concentration. Biological treatment lead to a 100-fold reduction in the number of E. coli but still more than a thousand E. coli colonies per 100ml of wastewater effluent reached the receiving water. The highest resistance was found in E. coli strains of raw wastewater and the lowest in isolates of treated wastewater effluent. Thus, wastewater treatment is an efficient barrier to decrease the residual FQ levels and the number of resistant bacteria entering ambient waters. Due to the lack of municipal wastewater treatment plants, the onsite treatment of hospital wastewater before discharging into municipal sewers should be considered as a viable option and consequently implemented.

  19. Desarrollo de métodos cromatográficos para la determinación de esteroides (corticoides y anabolizantes) en piensos y aguas de consumo animal

    OpenAIRE

    Muñiz Valencia, Roberto

    2011-01-01

    El objetivo principal de esta memoria es el desarrollo de procedimientos cromatográficos, mediante HPLC y GC-MS para el análisis de mezclas complejas de esteroides (corticoides y anabolizantes). Debido a la dificultad intrínseca en la separación de estos compuestos (gran similitud estructural) y dentro de este contexto, se estudian aquellas variables que pueden afectar a la separación cromatográfica. Con posterioridad, se aplicarán las separaciones obtenidas a la determinación de estos compue...

  20. Assessment of the efficacy of joint lavage versus joint lavage plus corticoids in patients with osteoarthritis of the knee.

    Science.gov (United States)

    Frías, Gabriel; Caracuel, Miguel Angel; Escudero, Alejandro; Rumbao, Jose; Pérez-Gujo, Veronica; del Carmen Castro, Maria; Font, Pilar; González, José; Collantes, Eduardo

    2004-06-01

    Joint lavage (JL), involves the passage of cold sterile 0.9% saline through the knee joint in order to have the fluid reach the inside of the joint capsule. This technique was evaluated as a local treatment for osteoarthritis (OA) of the knee alone (JL) and in combination with intra-articular infiltration with glucocorticoids (JLC). An overall 299 knees belonging to 205 patients (22% males, 78% females) with a mean age of 67 +/- 8 years and osteoarthritis of the knee of radiological grade II or III on the Kellgren scale were randomised in the ratio of 1:4 into two therapeutic groups, namely: JL (n = 62) and JLC (n = 237). All patients received joint lavage on day 0; in those of the JLC group, joint lavage was followed by infiltration of 40 mg of triamcinolone acetonide. The efficacy of both treatments was assessed by recording the corresponding values for the following variables: pain strength as measured by a visual analogy scale (VAS), effusion, crepitation, restricted motion, of osteoarthritis of the knee. spontaneous pain, pain on pressure, pain on passive motion and pain on active motion; all of these were recorded at the onset of the study, and after 1 and 3 months. There were no significant differences in the values of the variables at the different followup times. Also, pain severity was similar in both treatment groups. Thus, VAS for pain was 7.3 +/- 0.3 for the JL group and 7.1 +/- 0.2 for the JLC group at the onset, and decreased to 3.0 +/- 0.3 in the former and 2.8 +/- 0.2 in the latter after 1 month; the decrease was statistically significant in both cases. After 3 months, the JL and JLC groups had a VAS of 3.5 +/- 0.3 and 3.8 +/- 0.2, respectively. The results of this work suggest the absence of significant differences between the two treatments, such that both joint lavage alone and with infiltration with corticoids can be concluded as similarly effective for the symptomatic management

  1. Commodification and politicization of heritage: implications for heritage tourism at the Imperial Citadel of Thang Long, Hanoi (Vietnam)

    OpenAIRE

    Huong T. Bui; Lee, Timothy J.

    2015-01-01

    "The current study deconstructs the process of turning heritage resources into tourism products. A case study of the Central Sector of the Imperial Citadel of Thang Long, a UNESCO World Heritage site located in the capital city of Vietnam, Hanoi, provides an in-depth understanding of the plural use of heritage. Findings from the study reveal issues of heritage dissonance inherent in the process of resource selection, interpretation, and targeting for different audiences. It is apparent that c...

  2. Performance on the traditional and the touch screen, tablet versions of the Corsi Block and the Tower of Hanoi tasks

    OpenAIRE

    Robinson, Sarita Jane; Brewer, Gayle

    2016-01-01

    Psychologists routinely administer cognitive tasks to assess a range of mental abilities. In recent years, researchers and practitioners have employed new (i.e. digital) technologies to test cognitive performance, with tablet computer based tasks often replacing traditional versions. However, the extent to which findings from traditional and tablet based tasks are equivalent remains unclear. In the present study, sixty participants (18 men and 42 women) completed both the Tower of Hanoi and C...

  3. Comparação do corticoide inalatório e oral no tratamento da disfonia aguda Use of inhaled versus oral steroids for acute dysphonia

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    Andréa Moreira Veiga de Souza

    2013-04-01

    Full Text Available A disfonia aguda é um quadro comum na prática clínica. Seu tratamento, principalmente em adultos, não é bem definido na literatura. O corticoide é o tratamento medicamentoso mais recomendado. Os estudos existentes, entretanto, não são suficientes para a determinação da superioridade entre diferentes corticoides e a melhor forma de administração. OBJETIVO: Este estudo clínico prospectivo teve como objetivo comparar o efeito do corticoide inalatório na forma de pó seco com o efeito do corticoide oral, no tratamento da disfonia aguda. MÉTODO: Foram avaliados 32 pacientes adultos, divididos em dois grupos de 16 pacientes para cada um dos tratamentos, antes e após sete dias do uso da medicação. Os pacientes foram submetidos à videolaringosocpia e avaliação perceptiva e acústica da voz. RESULTADOS: O tratamento inalatório e oral reduziram significativamente a hiperemia, o edema e melhorou o movimento muco-ondulatório; entretanto, a redução do edema foi estatisticamente mais significativa (p = 0,012 nos pacientes tratados com a forma inalatória. A comparação dos valores da análise perceptiva auditiva e das medidas acústicas após tratamento entre os grupos, entretanto, não apresentou significância estatística. CONCLUSÃO: Houve melhora significativa da laringite aguda nas avaliações realizadas, em todos os pacientes estudados, com os dois tratamentos. O tratamento com corticoide inalatório foi significativamente mais efetivo na redução do edema.Acute dysphonia is a frequent condition in clinical practice. Its treatment, especially in adults, is not well established in the literature. Steroids are the most recommended drug treatment. However, the existing studies are not enough to establish superiority among the different steroids and the best route of administration. OBJECTIVE: This prospective clinical study aimed at comparing the effect of inhaling steroids as a dry powder with the effect of oral steroids to

  4. Finding Sex Partners Through Social Media Among Men Who Have Sex with Men in Hanoi, Vietnam.

    Science.gov (United States)

    Krishnan, Aparna; Nguyen, Minh; Giang, Le Minh; Ha, Tran Viet; Bhadra, Madhura; Nguyen, Sang Minh; Vu, Viet Duc; Nguyen, Quynh T; Miller, William C; Go, Vivian F

    2018-02-01

    Many men who have sex with men (MSM) in low and middle income countries search for male sexual partners via social media in part due to societal stigma and discrimination, yet little is known about the sexual risk profiles of MSM social media users. This cross-sectional study investigates the prevalence of social media use to find male sex partners in Hanoi, Vietnam and examines associations between social media use and sociodemographic and behavioral characteristics, including levels of internalized, perceived and enacted stigma, high-risk sexual behaviors, and HIV testing. 205 MSM were recruited from public venues where MSM congregate as well as through snowball sampling and completed an anonymous survey. MSM who found their male sexual partners using social media in the last year were more likely to have completed a university or higher degree (aOR 2.6; 95% CI 1.2-5.7), experience high levels of MSM-related perceived stigma (aOR 3.0; 95% CI 1.1-8.0), and have more than ten lifetime male sexual partners (aOR 3.2; 95% CI 1.3-7.6) compared to those who did not use social media. A niche for social media-based interventions integrating health and stigma-reduction strategies exists in HIV prevention programs for MSM.

  5. Characterisation and source apportionment of fine particulate sources at Hanoi from 2001 to 2008

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, D.D.; Crawford, J.; Stelcer, E.; Bac, V.T. [Australian Nuclear Science & Technology Organization, Menai, NSW (Australia)

    2010-01-15

    PM2.5 particulate matter has been collected on Teflon filters every Sunday and Wednesday at Hanoi, Vietnam for nearly eight years from April 2001 to December 2008. These filters have been analysed for over 21 different chemical species from hydrogen to lead by ion beam analysis techniques. This is the first long term PM2.5 dataset for this region. The average PM2.5 mass for the study period was (54 {+-} 33) {mu} g m{sup -3}, well above the current US EPA health goal of 15 {mu} g m{sup -3}. The average PM2.5 composition was found to be (29 {+-} 8)% ammonium sulfate, (8.9 {+-} 3.3)% soil, (28 {+-} 11)% organic matter, (0.6 {+-} 1.4)% salt and (9.2 {+-} 2.8)% black carbon. The remaining missing mass (25%) was mainly nitrates and absorbed water. Positive matrix factorisation techniques identified the major source contributions to the fine mass as automobiles and transport (40 {+-} 10)%, windblown soil (3.4 {+-} 2)%, secondary sulfates (7.8 {+-} 10)%, smoke from biomass burning (13 {+-} 6)%, ferrous and cement industries (19 {+-} 8)%, and coal combustion (17 {+-} 7)% during the 8 year study period.

  6. Prevalence of malnutrition in patients admitted to a major urban tertiary care hospital in Hanoi, Vietnam.

    Science.gov (United States)

    Huong, Pham Thi Thu; Lam, Nguyen Thi; Thu, Nghiem Nguyet; Quyen, Tran Chau; Lien, Dinh Thi Kim; Anh, Nguyen Quoc; Henry, Elizabeth G; Oliver, Lauren; Apovian, Caroline M; Ziegler, Thomas R; Lenders, Carine

    2014-01-01

    To determine the prevalence of malnutrition using anthropometric measures among hospitalized pediatric and adult patients admitted at Bach Mai Hospital, Hanoi, Vietnam. A one-day cross-sectional survey was used in selected wards (Pediatrics, Surgery, Intensive Care Unit, Renal Diseases, Gastroenterology Diseases, Respiratory Diseases, and Endocrinology). Unavailable patients and those discharged within 24 hours were excluded. Anthropometric data included body weight, height (or length), and mid-upper arm circumference. The type, severity, and prevalence rate of malnutrition were defined based on World Health Organization (WHO) criteria. The sample was hospitalized children and adults: 108 and 571 were children aged 6 months to 18.9 years old and adult patients, respectively. The overall rate of pediatric wasting (weight-for-height ≤ -2 SD or BMI ≤ -2 SD, kg/m²) was 19.0% (n= 19/100) and that of stunting (height-for-age ≤ -2 SD) was 13.9% (n=14/101). Using either the mid-upper arm circumference prevalence of under-nutrition (BMIprevalence of under-nutrition, 40.9% (n=38/93). The prevalence of malnutrition was high in this cohort of hospitalized patients, particularly in adults, but comparable to other published reports. Obesity was nearly nonexistent in both children and adults.

  7. Factors associated with nosocomial SARS-CoV transmission among healthcare workers in Hanoi, Vietnam, 2003

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    Leitmeyer Katrin C

    2006-08-01

    Full Text Available Abstract Background In March of 2003, an outbreak of Severe Acute Respiratory Syndrome (SARS occurred in Northern Vietnam. This outbreak began when a traveler arriving from Hong Kong sought medical care at a small hospital (Hospital A in Hanoi, initiating a serious and substantial transmission event within the hospital, and subsequent limited spread within the community. Methods We surveyed Hospital A personnel for exposure to the index patient and for symptoms of disease during the outbreak. Additionally, serum specimens were collected and assayed for antibody to SARS-associated coronavirus (SARS-CoV antibody and job-specific attack rates were calculated. A nested case-control analysis was performed to assess risk factors for acquiring SARS-CoV infection. Results One hundred and fifty-three of 193 (79.3% clinical and non-clinical staff consented to participate. Excluding job categories with Conclusion This study highlights job categories and activities associated with increased risk for SARS-CoV infection and demonstrates that a broad diversity of hospital workers may be vulnerable during an outbreak. These findings may help guide recommendations for the protection of vulnerable occupational groups and may have implications for other respiratory infections such as influenza.

  8. Avian Influenza H5N1 and the Wild Bird Trade in Hanoi, Vietnam

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    F. Brooks-Moizer

    2009-06-01

    Full Text Available Wildlife trade and emerging infectious diseases pose significant threats to human and animal health and global biodiversity. Legal and illegal trade in domestic and wild birds has played a significant role in the global spread of highly pathogenic avian influenza H5N1, which has killed more than 240 people, many millions of poultry, and an unknown number of wild birds and mammals, including endangered species, since 2003. This 2007 study provides evidence for a significant decline in the scale of the wild bird trade in Hanoi since previous surveys in 2000 (39.7% decline and 2003 (74.1% decline. We attribute this to the enforcement of Vietnam's Law 169/2005/QD UBND, introduced in 2005, which prohibits the movement and sale of wild and ornamental birds in cities. Nevertheless, 91.3% (21/23 of bird vendors perceived no risk of H5N1 infection from their birds, and the trade continues, albeit at reduced levels, in open market shops. These findings highlight the importance of continued law enforcement to maintain this trade reduction and the associated benefits to human and animal health and biodiversity conservation.

  9. Prediction of outcome after moderate and severe traumatic brain injury: External validation of the International Mission on Prognosis and Analysis of Clinical Trials (IMPACT) and Corticoid Randomisation after Significant Head injury (CRASH) prognostic models

    NARCIS (Netherlands)

    B. Roozenbeek (Bob); H.F. Lingsma (Hester); F.E. Lecky (Fiona); J. Lu (Juan); J. Weir (James); I. Butcher (Isabella); G.S. McHugh (Gillian); G.D. Murray (Gordon); P. Perel (Pablo); A.I.R. Maas (Andrew); E.W. Steyerberg (Ewout)

    2012-01-01

    textabstractObjective: The International Mission on Prognosis and Analysis of Clinical Trials and Corticoid Randomisation After Significant Head injury prognostic models predict outcome after traumatic brain injury but have not been compared in large datasets. The objective of this is study is to

  10. Interleukin-17- and interleukin-22-secreting myelin-specific CD4(+) T cells resistant to corticoids are related with active brain lesions in multiple sclerosis patients.

    Science.gov (United States)

    Wing, Ana Cristina; Hygino, Joana; Ferreira, Thais B; Kasahara, Taissa M; Barros, Priscila O; Sacramento, Priscila M; Andrade, Regis M; Camargo, Solange; Rueda, Fernanda; Alves-Leon, Soniza V; Vasconcelos, Claudia Cristina; Alvarenga, Regina; Bento, Cleonice A M

    2016-02-01

    Multiple sclerosis (MS) is thought to be an autoimmune disorder. It is believed that immunological events in the early stages have great impact on the disease course. Therefore, we aimed to evaluate the cytokine profile of myelin basic protein (MBP)-specific T cells from MS patients in the early phase of the disease and correlate it to clinical parameters, as well as to the effect of in vitro corticoid treatment. Peripheral T cells from MS patients were stimulated with MBP with our without hydrocortisone for 5 days. The cytokines level were determined by ELISA. The number of active brain lesions was determined by MRI scans, and the neurological disabilities were assessed by Expanded Disability Status Scale scores. Our results demonstrated that MS-derived T cells responded to MBP by producing high levels of T helper type 1 (Th1) and Th17 cytokines. Although the production of interleukin-6 (IL-6), granulocyte-macrophage colony-stimulating factor, IL-17 and IL-22 was less sensitive to hydrocortisone inhibition, only IL-17 and IL-22 levels correlated with active brain lesions. The ability of hydrocortisone to inhibit IL-17 and IL-22 production by MBP-specific CD4(+) T cells was inversely related to the number of active brain lesions. Finally, the production of both cytokines was significantly higher in cell cultures from Afrodescendant patients and it was less sensitive to hydrocortisone inhibition. In summary, our data suggest that IL-17- and IL-22-secreting CD4(+) T cells resistant to corticoids are associated with radiological activity of the MS in early stages of the disease, mainly among Afrodescendant patients who, normally, have worse prognosis. © 2015 John Wiley & Sons Ltd.

  11. Impact of Urban Heat Island under the Hanoi Master Plan 2030 on Cooling Loads in Residential Buildings

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    Tran Hoang Hai Nam

    2015-01-01

    Full Text Available This study aims to evaluate the influence of urban heat island (UHI under the Hanoi Master Plan 2030 on the energy consumption for space cooling in residential buildings. The weather conditions under the current and future status (master plan condition simulated in the previous study (Trihamdani et al., 2014 were used and cooling loads in all the residential buildings in Hanoi over the hottest month were estimated under the simulated current and future conditions by using the building simulation program, TRNSYS (v17. Three most typical housing types in the city were selected for the simulation. The cooling loads of respective housing types were obtained in each of the districts in Hanoi. The results show that the total cooling loads over June 2010 is approximately 683 Terajoule (TJ under the current status, but it is predicted to increase to 903 TJ under the master plan condition. The increment is largely due to the increase in number of households (203 TJ or 92%, but partially due to the increase in urban temperature, i.e. UHI effect (17 TJ or 8%. The increments in new built-up areas were found to be larger than those in existing built-up areas. The cooling load in apartment is approximately half of that in detached house, which is approximately half of that in row house. Moreover, it was seen that although sensible cooling loads increased with the increase in outdoor temperature, the latent cooling loads decreased due to the decrease in absolute humidity and the increase in air temperature.

  12. Interaction between surface water areas and groundwater in Hanoi city, Viet Nam

    Science.gov (United States)

    Hayashi, T.; Kuroda, K.; Do Thuan, A.; Tran Thi Viet, N.; Takizawa, S.

    2012-12-01

    Hanoi is the capital of Viet Nam and the second largest city in this country (population: 6.45 million in 2009). Hanoi city has developed along the Red River and has many lakes, ponds and canals. However, recent rapid urbanization of this city has reduced number of natural water areas such as ponds and lakes by reclamation not only in the central area but the suburban area. Canals also have been reclaimed or cut into pieces. Contrary, number of artificial water areas such as fish cultivation pond has rapidly increased. On the other hand, various kind of waste water flows into these natural and artificial water areas and induces pollution and eutrophication. These waste waters also have possibility of pollution of groundwater that is one of major water resources in this city. In addition, groundwater in this area has high concentrations of Arsenic, Fe and NH4. Thus, groundwater use may causes re-circulation of Arsenic. However, studies on the interaction between surface water areas and groundwater and on the role of surface water areas for solute transport with water cycle are a few. Therefore, we focused on these points and took water samples of river, pond and groundwater from four communities in suburban areas: two communities are located near the Red River and other two are far from the River. Also, columnar sediment samples of these ponds were taken and pore water was abstracted. Major dissolved ions, metals and stable isotopes of oxygen and hydrogen of water samples were analyzed. As for water cycle, from the correlation between δ18O and δD, the Red River water (after GNIR) were distributed along the LMWL (δD=8.2δ18O+14.1, calculated from precipitation (after GNIP)). On the other hand, although the pond waters in rainy season were distributed along the LMWL, that in dry season were distributed along the local evaporation line (LEL, slope=5.6). The LEL crossed with the LMWL at around the point of weighted mean values of precipitation in rainy season and of

  13. Atmospheric heavy metal deposition in Northern Vietnam: Hanoi and Thainguyen case study using the moss biomonitoring technique, INAA and AAS.

    Science.gov (United States)

    Viet, Hung Nguyen; Frontasyeva, Marina Vladimirovna; Thi, Thu My Trinh; Gilbert, Daniel; Bernard, Nadine

    2010-06-01

    The moss technique is widely used to monitor atmospheric deposition of heavy metals in many countries in Europe, whereas this technique is scarcely used in Asia. To implement this international reliable and cheap methodology in the Asian countries, it is necessary to find proper moss types typical for the Asian environment and suitable for the biomonitoring purposes. Such a case study was undertaken in Vietnam for assessing the environmental situation in strongly contaminated areas using local species of moss Barbula indica. The study is focused on two areas characterized by different pollution sources: the Hanoi urban area and the Thainguyen metallurgical zone. Fifty-four moss samples were collected there according to standard sampling procedure adopted in Europe. Two complementary analytical techniques, atomic absorption spectrometry (AAS) and instrumental neutron activation analysis (INAA), were used for determination of elemental concentrations in moss samples. To characterize the pollution sources, multivariate statistical analysis was applied. A total of 38 metal elements were determined in the moss by the two analytical techniques. The results of descriptive statistics of metal concentration in moss from the city center and periphery of Hanoi determined by AAS are presented. The similar results for moss from Thainguyen province determined by INAA and AAS are given also. A comparison of mean elemental concentrations in moss of this work with those in different environmental conditions of other authors provides reasonable information on heavy metal atmospheric deposition levels. Factor loadings and factor scores were used to identify and apportion contamination sources at the sampling sites. The values of percentage of total of factors show two highly different types of pollution in the two examined areas-the Hanoi pollution composition with high portion of urban-traffic activity and soil dust (62%), and the one of Thainguyen with factors related to industrial

  14. "Doi moi" and private pharmacies: a case study on dispensing and financial issues in Hanoi, Vietnam.

    Science.gov (United States)

    Chuc, N T; Tomson, G

    1999-06-01

    Vietnam, a developing country, has had comparatively good health and human survival at low cost. The economic reform changed the health care system, and private pharmacies during the last 5 years have taken over a majority of the drug distribution. Problems include weaknesses in drug regulation and reported increases in antibiotic resistance. This case study, a purposive sample of two private pharmacies in Hanoi, explored management, including dispensing, inventory and financing, using the concept of triangulation. Observations and interviews of customers were complemented by stock inventory and interviews of the pharmacy staff. Drugs were classified according to the ATC code and the essential drug list of Vietnam. Pretested protocols were used. In all 1833 encounters were studied during the 2 weeks, out of which 286 were children. Less than 1% of customers came with prescriptions and 94.9% decided by themselves which drugs to buy. Antibiotics represented 17%, of which 90% were broad spectrum. Ampicillin dominated, both in children and adults. Some 50% of the antibiotics were given for 2.5 days or less. Less than 50% of the drugs were essential drugs (ED) on dispensing and even less on inventory. Antibiotics and vitamins were the most commonly sold drugs and, overall, brand names dominated. Little if any drug information was observed. Antibiotics were said to represent the most profitable drugs, according to the pharmacy staff. More than 20% of all products were combination drugs, including irrational and popular products with antibiotics and corticosteroids and combinations of aspirin, phenacetin and caffeine. This study shows an unexpectedly high proportion of customers, being "Tu Lam Bac Sy" (their own doctors), deciding themselves which drugs to buy. Although the "Doi moi" renovation has led to much improved drug availability, at least in urban setting, our case study highlights major problems in need of urgent actions. In particular the prevailing practices

  15. Life time suicidal thoughts in an urban community in Hanoi, Vietnam

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    Leenaars Antoon

    2006-03-01

    Full Text Available Abstract Background Suicidal thought is a risk factor and a stage in the suicidal process from planning to attempting and dying by suicide. To date, studies on suicidal thought in the general population, especially in Asian communities, have been limited. Method The WHO SUPRE-MISS (the multisite intervention study on suicidal behaviours community survey questionnaire was filled in for 2,280 randomly selected residents of the DongDa district of Hanoi, Vietnam by means of face-to-face interviews. This multi-factor questionnaire includes such variables as sociodemographic information, suicidal thought and history of suicide attempts, physical health, alcohol consumption and medication. Results Prevalence rates for life time suicidal thoughts, suicide plans and suicide attempts were 8.9%, 1.1% and 0.4% respectively. Suicidal thoughts are associated with multiple characteristics, such as female gender, single/widowed/separated/divorced marital status, low income, lifestyle (use of alcohol, sedatives and pain relief medication, but not with low education or employment status. Having no religion and being a Buddhist appear to be protective factors for suicidal thought. The ratio of suicidal thoughts, suicide plans and suicide attempts on a lifetime basis is 22.3:2.8:1. Conclusion In Vietnam, as in Western and other Asian countries, suicidal thoughts are associated with similar negative psychosocial risk factors, lifestyle and emotional problems, which implies that suicide preventive measure developed elsewhere can be adjusted to Vietnamese condition. Understanding the unique and common risks in a culture may assist in prediction and control.

  16. Alumni survey of Masters of Public Health (MPH training at the Hanoi School of Public Health

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    Nguyen Ha

    2007-10-01

    Full Text Available Abstract Background 1 To elicit the opinions of the Public Health alumni of the MPH program; 2 To assess the applicability of the knowledge and skills acquired; 3 To identify the frequency of the public health competencies that the alumni performed. Methods We requested 187 graduates to complete a self-administered questionnaire and conducted in-depth interviews with 8 alumni as well as a focus group discussion with 14 alumni. Results In total 79.1% (148 of the MPH graduates completed and returned the questionnaire. Most alumni (91% agreed that the MPH curriculum corresponded with the working requirements of public health professionals; and nearly all were satisfied with what they have learnt (96%. Most respondents said that the MPH program enabled them to develop relevant professional skills (95% and that they were satisfied with the curriculum (90%. Notably fewer respondents (73% felt that the MPH program structure was balanced and well designed. Most alumni (64.3% were satisfied with Hanoi School of Public Health (HSPH full-time lecturers; but even more (83% were satisfied with visiting lecturers. The most commonly selected of the 34 pre-identified public health competencies were: applying computer skills (66.4%, planning and managing health programs (47.9%, communicating with the community and/or mobilizing the community to participate in health care (43.2%. Overall, the MPH alumni felt that HSPH emphasized research methods at the expense of some management and operational competencies. The most important challenges at work identified by the alumni were insufficient skills in: data analysis, decision making, inter-sectoral cooperation development, English language and training. Conclusion The training program should be reviewed and revised to meet the needs of its graduates who enter diverse situations and positions. English language skills were identified as top priority for further emphasis. The training program should comply with a more

  17. Left-handers look before they leap: Handedness influences reactivity to novel Tower of Hanoi Tasks

    Directory of Open Access Journals (Sweden)

    Lynn eWright

    2015-02-01

    Full Text Available A sample of 203 task naïve left- and right-handed participants were asked to complete a combination of the three and four disk Towers of Hanoi (ToH, manipulating novelty and complexity. Self-reported state anxiety and latency to respond (initiation time were recorded before each ToH.Novelty had a major effect on initiation time, particularly for left-handers. Left-handers had a longer latency to start and this was significantly longer on the first trial. Irrespective of hand-preference, initiation time reduced on the second trial, however this was greatest for left-handers. Condition of task did not systematically influence initiation time for right handers, but did for left-handers. State anxiety was influenced by task novelty and complexity in a more complicated way. During the first trial, there was a significant handedness x number of disks interaction with left-handers having significantly higher state anxiety levels before the three-disk ToH. This suggests that the initial reaction to this task for left-handers was not simply due to perceived difficulty. On their second trial, participants completing a novel ToH had higher state anxiety scores than those completing a repeated version. Overall, left-handers had a larger reduction in their state anxiety across trials. Relating to this, the expected strong positive correlation between state and trait anxiety was absent for left-handed females in their first tower presentation, but appeared on their second. This was driven by low trait anxiety individuals showing a higher state anxiety response in the first (novel trial, supporting the idea that left-handed females respond to novelty in a way that is not directly a consequence of their trait anxiety. A possible explanation may be stereotype threat influencing the behaviour of left-handed females.

  18. Left-handers look before they leap: handedness influences reactivity to novel Tower of Hanoi tasks.

    Science.gov (United States)

    Wright, Lynn; Hardie, Scott M

    2015-01-01

    A sample of 203 task naïve left- and right-handed participants were asked to complete a combination of the 3- and 4-disk Towers of Hanoi (ToH), manipulating novelty and complexity. Self-reported state anxiety and latency to respond (initiation time) were recorded before each ToH. Novelty had a major effect on initiation time, particularly for left-handers. Left-handers had a longer latency to start and this was significantly longer on the first trial. Irrespective of hand-preference, initiation time reduced on the second trial, however, this was greatest for left-handers. Condition of task did not systematically influence initiation time for right handers, but did for left-handers. State anxiety was influenced by task novelty and complexity in a more complicated way. During the first trial, there was a significant handedness × number of disks interaction with left-handers having significantly higher state anxiety levels before the 3-disk ToH. This suggests that the initial reaction to this task for left-handers was not simply due to perceived difficulty. On their second trial, participants completing a novel ToH had higher state anxiety scores than those completing a repeated version. Overall, left-handers had a larger reduction in their state anxiety across trials. Relating to this, the expected strong positive correlation between state and trait anxiety was absent for left-handed females in their first tower presentation, but appeared on their second. This was driven by low trait anxiety individuals showing a higher state anxiety response in the first (novel) trial, supporting the idea that left-handed females respond to novelty in a way that is not directly a consequence of their trait anxiety. A possible explanation may be stereotype threat influencing the behavior of left-handed females.

  19. The costs of traumatic brain injury due to motorcycle accidents in Hanoi, Vietnam

    Directory of Open Access Journals (Sweden)

    Vo Thuy TN

    2008-08-01

    Full Text Available Abstract Background Road traffic accidents are the leading cause of fatal and non-fatal injuries in Vietnam. The purpose of this study is to estimate the costs, in the first year post-injury, of non-fatal traumatic brain injury (TBI in motorcycle users not wearing helmets in Hanoi, Vietnam. The costs are calculated from the perspective of the injured patients and their families, and include quantification of direct, indirect and intangible costs, using years lost due to disability as a proxy. Methods The study was a retrospective cross-sectional study. Data on treatment and rehabilitation costs, employment and support were obtained from patients and their families using a structured questionnaire and The European Quality of Life instrument (EQ6D. Results Thirty-five patients and their families were interviewed. On average, patients with severe, moderate and minor TBI incurred direct costs at USD 2,365, USD 1,390 and USD 849, with time lost for normal activities averaging 54 weeks, 26 weeks and 17 weeks and years lived with disability (YLD of 0.46, 0.25 and 0.15 year, respectively. Conclusion All three component costs of TBI were high; the direct cost accounted for the largest proportion, with costs rising with the severity of TBI. The results suggest that the burden of TBI can be catastrophic for families because of high direct costs, significant time off work for patients and caregivers, and impact on health-related quality of life. Further research is warranted to explore the actual social and economic benefits of mandatory helmet use.

  20. Nutritional status and feeding practices in gastrointestinal surgery patients at Bach Mai Hospital, Hanoi, Vietnam

    Science.gov (United States)

    Young, Lorraine S; Huong, Pham Thi Thu; Lam, Nguyen Thi; Thu, Nghiem Nguyet; Van, Ha Thi; Hanh, Nguyen Lien; Tuyen, Le Danh; Lien, Dinh Thi Kim; Hoc, Tran Hieu; Tuyet, Chu Thi; Anh, Nguyen Quoc; Henry, Elizabeth G; Lenders, Carine M; Gura, Kathleen M; Bigornia, Sherman J; Apovian, Caroline M; Ziegler, Thomas R

    2017-01-01

    Background and Objectives The nutritional status and hospital feeding practices of surgical patients in Vietnam are not well documented. Based on a cross-sectional study at Bach Mai Hospital (BMH), the prevalence of malnutrition was found to be 33% in the surgical ward using a body mass index (BMI<18.5 kg/m2. We conducted an observational study over a three month period to evaluate the feeding practices in the gastrointestinal (GI) surgery ward at Bach Mai Hospital (BMH) in Hanoi, Vietnam. Methods and Study Design Investigators from the U.S. and the Vietnamese National Institute of Nutrition (NIN) enrolled 72 subjects admitted for elective GI surgery in an observational study at BMH. Baseline anthropometrics and changes over time, body mass index (BMI), Subjective Global Assessment (SGA) and daily kcal and protein intake from oral diet, tube feeding, and parenteral nutrition (PN) from admission until discharge were documented. Results A total of 50% of subjects scored a B or C on the SGA; 48% of subjects had a BMI<18.5, while mean mid upper arm circumference was in the low-normal range (24±4 cm). Nearly all patients (98%) were given PN postoperatively, with oral feeding starting on an average of postoperative day 4. Only one patient was tube fed. Mean daily total calorie intake was 15 kcal/kg/day and protein intake was 0.61 g/kg/day during hospitalization. Micronutrient supplementation was minimal in subjects receiving PN. Conclusions Hospital malnutrition in surgical patients in Vietnam is a significant problem, peri-operative feeding appears suboptimal and use of early postoperative PN was routine. PMID:27440685

  1. Mobile phone use among motorcyclists and electric bike riders: A case study of Hanoi, Vietnam.

    Science.gov (United States)

    Truong, Long T; Nguyen, Hang T T; De Gruyter, Chris

    2016-06-01

    Motorcyclist injuries and fatalities are a major concern of many developing countries. In Vietnam, motorcycles are involved in more than 70% of all road traffic crashes. This paper aims to explore the prevalence and factors associated with mobile phone use among motorcyclists and electric bike riders, using a case study of Hanoi, Vietnam. A cross-sectional observation survey was undertaken at 12 sites, in which each site was surveyed during a two-hour peak period from 16:30 to 18:30 for two weekdays and one weekend day. A total of 26,360 riders were observed, consisting of 24,759 motorcyclists and 1601 electric bike riders. The overall prevalence of mobile phone use while riding was 8.4% (95% CI: 8.06-8.74%) with calling having higher prevalence than screen operation: 4.64% (95% CI: 4.39-4.90%) vs. 3.76% (95% CI: 3.52-3.99%) respectively. Moreover, the prevalence of mobile phone use was higher among motorcyclists than electric bike riders: 8.66% (95%CI: 8.30-9.01%) vs. 4.43% (95% CI: 3.40-5.47%) respectively. Logistic regression analyses revealed that mobile phone use while riding was associated with vehicle type, age, gender, riding alone, weather, day of week, proximity to city centre, number of lanes, separate car lanes, red traffic light duration, and police presence. Combining greater enforcement of existing legislations with extensive education and publicity programs is recommended to reduce potential deaths and injuries related to the use of mobile phones while riding. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Key parameters for behaviour related to source separation of household organic waste: A case study in Hanoi, Vietnam.

    Science.gov (United States)

    Kawai, Kosuke; Huong, Luong Thi Mai

    2017-03-01

    Proper management of food waste, a major component of municipal solid waste (MSW), is needed, especially in developing Asian countries where most MSW is disposed of in landfill sites without any pretreatment. Source separation can contribute to solving problems derived from the disposal of food waste. An organic waste source separation and collection programme has been operated in model areas in Hanoi, Vietnam, since 2007. This study proposed three key parameters (participation rate, proper separation rate and proper discharge rate) for behaviour related to source separation of household organic waste, and monitored the progress of the programme based on the physical composition of household waste sampled from 558 households in model programme areas of Hanoi. The results showed that 13.8% of 558 households separated organic waste, and 33.0% discharged mixed (unseparated) waste improperly. About 41.5% (by weight) of the waste collected as organic waste was contaminated by inorganic waste, and one-third of the waste disposed of as organic waste by separators was inorganic waste. We proposed six hypothetical future household behaviour scenarios to help local officials identify a final or midterm goal for the programme. We also suggested that the city government take further actions to increase the number of people participating in separating organic waste, improve the accuracy of separation and prevent non-separators from discharging mixed waste improperly.

  3. Kick the pesticide habit: forces affecting pesticide use and pesticide policy in the fringe of Hanoi and Nanjing, stakeholders' perspectives and policy recommendations

    NARCIS (Netherlands)

    Belder, den E.; Shi Xiaoping, X.; Dihn Ti Hai Van,; Tran Manh Tuong,; Nooy-van Tol, J.

    2006-01-01

    This study intends to contribute in the effort to develop a more rational crop protection strategy and an environmentally sound production in the fringe of Nanjing (China) and Hanoi (Vietnam). This paper reports on the first results of a research project jointly executed in China and Vietnam by

  4. Photo-oxidative degradation of motorcycle helmets in Hanoi, Vietnam: A prospective preliminary study.

    Science.gov (United States)

    Ramli, Roszalina; Che Man, Zuraidah; Nordin, Rifqah; Abdul Karim, Fadzlina; Rashdi, Muhd Fazlynizam; Oxley, Jennie; Viet Cuong, Pham

    2016-09-01

    Vietnamese spend hours travelling on the road using their motorcycles. Their helmets are exposed continuously to sunlight and rain. The objectives of this study were to determine the association between the effect of photo-oxidative degradation (POD) of the outer shells and helmet age on helmet damage. The micro-structural change of the outer shell was also investigated. This was a prospective, cross sectional study recruiting injured motorcyclists from Hanoi, Vietnam hospital. The participants were interviewed by a trained researcher. The participants' helmets were collected post-crash. Initially, the helmets were examined for their type and external characteristics. A 3 cm × 3 cm cut was made on the helmet in the impacted and non-impacted areas (control). These areas were investigated for evidence of POD and presence of micro-cracks and material disintegration. 50 participants were enrolled. Sources of information included questionnaire and laboratory analyses. The helmet factors of interest were age of the helmet, exposure of helmet to sunlight and rain (duration/day) and history of previous impact. Laboratory analyses included Fourier Transform Infra Red (FTIR) for degradation and scanning electron microscopy (SEM) for micro-structural examination. Majority of the helmets was the open-face type, 40 (80.0%). 31 (62.0%) helmets aged less than three years (LTY) and 19 (38.0%) were three years old or more (MTY). 19 (61.3%) of the LTY helmets and 12 (63.2%) MTY helmets showed evidence of POD. The duration of helmet exposure to sunlight was between 93 to 6570 hours (mean 2347.74 hours; SD 1733.39). The SEM showed 15 helmets (30%) with micro-fractures, 21 helmets (42.0%) with material disintegration. Prolonged uv exposure to the ABS helmets resulted in changes in the helmet material in the form of material disintegration and microcracks and this association was statistically significant (p = 0.03). POD occurs due to routine exposure to the ultraviolet light

  5. [Implementation of a continuum of care for people living with HIV/AIDS in Hanoi (Vietnam)].

    Science.gov (United States)

    de Loenzien, Myriam

    2009-01-01

    Caring for people living with HIV/AIDS (PLWHA) encompasses various tasks, from prevention to palliative care. It involves a set of consistent and coordinated actions. This article presents the first free-of-charge management programme including antiretroviral treatment in Vietnam (as opposed to research and evaluation programmes). It was launched in 2004 in Hanoi. Our study was conducted in 2003-2004 as part of a collaborative research programme led by IRD (Research Institute for Development) and the National Economic University in Hanoi and was funded by ESTHER (Together for a Therapeutic Solidarity in Hospital Network) group. Data collection included 68 qualitative interviews with patients, members of their families and members of the hospital staff, observations of outpatient consultations, and analysis of inpatient files. The results show that patients, their families and hospital staff members all perceive a comprehensive care and treatment programme as very important and consider that it should include social and psychological care as well as an integrated set of actions involving various types of participants. Outpatient and inpatient care are closely linked: they take place in the same hospital department, they involve patients with similar social and demographic characteristics marked by multiple risk behaviours and recourse to several kinds of healthcare services. The observation of outpatient consultations showed the limitations of strictly biomedical care to which social and psychological care were added only lately. One of the principal difficulties is patients' difficulties in keeping their outpatient appointments. Overall, patients consider themselves lucky to able to receive care and treatment with antiretroviral drugs. They nevertheless complain about the lack of social and psychological support, which they expect should help them to tolerate and adapt to their biomedical treatment and to include counselling and information about this treatment and

  6. Regulation of Corticoid and Serotonin Receptor Brain System following Early Life Exposure of Glucocorticoids: Long Term Implications for the Neurobiology of Mood

    Science.gov (United States)

    Vázquez, Delia M.; Neal, Charles R.; Patel, Paresh D.; Kaciroti, Niko; López, Juan F.

    2011-01-01

    Potent glucocorticoids (GC) administered early in life has improved premature infant survival dramatically. However, these agents may increase the risk for physical, neurological and behavior alterations. Anxiety, depression and attention difficulties are commonly described in adolescent and young adult survivors of prematurity. In the present study we administered vehicle, dexamethasone, or hydrocortisone to Sprague-Dawley rat pups on postnatal days 5 and 6, mimicking a short term clinical protocol commonly used in human infants. Two systems that are implicated in the regulation of stress and behavior were assessed: the limbic-hypothalamic-pituitary-adrenal axis [LHPA, glucocorticoid and mineralocorticoid receptors within] and the Serotonin (5-HT) system. We found that as adults, male Sprague-Dawley pups treated with GC showed agent specific altered growth, anxiety-related behavior, changes in corticoid response to novelty and gene expression changes within LHPA and 5-HT–related circuitry. The data suggest that prolonged GC-receptor stimulation during the early neonatal period can contribute to the development of individual differences in stress response and anxiety-related behavior later in life. PMID:21855221

  7. Air Pollution Modeling at Road Sides Using the Operational Street Pollution Model-A Case Study in Hanoi, Vietnam

    DEFF Research Database (Denmark)

    Hung, Ngo Tho; Ketzel, Matthias; Jensen, Steen Solvang

    2010-01-01

    the operational street pollution model (OSPM) developed by the National Environmental Research Institute in Denmark for a case study in Hanoi, the capital of Vietnam. OSPM predictions from five streets were evaluated against air pollution measurements of nitrogen oxides (NO), sulfur dioxide (SO2), carbon monoxide......In many metropolitan areas, traffic is the main source of air pollution. The high concentrations of pollutants in streets have the potential to affect human health. Therefore, estimation of air pollution at the street level is required for health impact assessment. This task has been carried out...... for the street-scale air pollution modeling in Vietnam, namely by providing reliable emission factors and hourly air pollution measurements of high quality....

  8. Disease burden due to gastrointestinal infections among people living along the major wastewater system in Hanoi, Vietnam

    DEFF Research Database (Denmark)

    Fuhrimann, Samuel; Nauta, Maarten; Pham-Duc, Phuc

    2017-01-01

    Background: Despite recent improvements of wastewater treatment capacities in urban areas of Hanoi, Vietnam, microbial pollution is still considerable. There is a paucity of burden estimates due to gastrointestinal infection in people living along the wastewater system, and among people who...... conveyance and treatment systems; (ii) urban farmers using wastewater from To Lich River; (iii) community members in urban areas exposed to flooding events in the districts of Hoang Mai and Thanh Tri; and (iv) peri-urban farmers in Thanh Tri district, where Red River water is used for agriculture......, pathogenic . Salmonella spp., . Cryptosporidium spp. and . Ascaris lumbricoides were employed to estimate annual risk of gastrointestinal infection and disease burden. Results: The QMRA estimated a disease burden of 0.011 disability-adjusted life years (DALYs) per person per year in urban farmers, 0...

  9. Commodification and Politicization of Heritage: Implications for Heritage Tourism at the Imperial Citadel of Thang Long, Hanoi (Vietnam

    Directory of Open Access Journals (Sweden)

    Huong T. Bui

    2015-12-01

    Full Text Available The current study deconstructs the process of turning heritage resources into tourism products. A case study of the Central Sector of the Imperial Citadel of Thang Long, a UNESCO World Heritage site located in the capital city of Vietnam, Hanoi, provides an in-depth understanding of the plural use of heritage. Findings from the study reveal issues of heritage dissonance inherent in the process of resource selection, interpretation, and targeting for different audiences. It is apparent that commodification cannot be separated from the politicization of heritage. In the case of heritage of national importance and international significance, politicization has been prioritized and results in diminishing the utilization of heritage for commercial purposes such as tourism.

  10. Acute effects of ambient air pollution on lower respiratory infections in Hanoi children: An eight-year time series study.

    Science.gov (United States)

    Nhung, Nguyen Thi Trang; Schindler, Christian; Dien, Tran Minh; Probst-Hensch, Nicole; Perez, Laura; Künzli, Nino

    2018-01-01

    Lower respiratory diseases are the most frequent causes of hospital admission in children worldwide, particularly in developing countries. Daily levels of air pollution are associated with lower respiratory diseases, as documented in many time-series studies. However, investigations in low-and-middle-income countries, such as Vietnam, remain sparse. This study investigated the short-term association of ambient air pollution with daily counts of hospital admissions due to pneumonia, bronchitis and asthma among children aged 0-17 in Hanoi, Vietnam. We explored the impact of age, gender and season on these associations. Daily ambient air pollution concentrations and hospital admission counts were extracted from electronic databases received from authorities in Hanoi for the years 2007-2014. The associations between outdoor air pollution levels and hospital admissions were estimated for time lags of zero up to seven days using Quasi-Poisson regression models, adjusted for seasonal variations, meteorological variables, holidays, influenza epidemics and day of week. All ambient air pollutants were positively associated with pneumonia hospitalizations. Significant associations were found for most pollutants except for ozone and sulfur dioxide in children aged 0-17. Increments of an interquartile range (21.9μg/m 3 ) in the 7-day-average level of NO 2 were associated with a 6.1% (95%CI 2.5% to 9.8%) increase in pneumonia hospitalizations. These associations remained stable in two-pollutant models. All pollutants other than CO were positively associated with hospitalizations for bronchitis and asthma. Associations were stronger in infants than in children aged 1-5. Strong associations between hospital admissions for lower respiratory infections and daily levels of air pollution confirm the need to adopt sustainable clean air policies in Vietnam to protect children's health. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  11. Groundwater recharge in suburban areas of Hanoi, Vietnam: effect of decreasing surface-water bodies and land-use change

    Science.gov (United States)

    Kuroda, Keisuke; Hayashi, Takeshi; Do, An Thuan; Canh, Vu Duc; Nga, Tran Thi Viet; Funabiki, Ayako; Takizawa, Satoshi

    2017-05-01

    Over-exploited groundwater is expected to remain the predominant source of domestic water in suburban areas of Hanoi, Vietnam. In order to evaluate the effect on groundwater recharge, of decreasing surface-water bodies and land-use change caused by urbanization, the relevant groundwater systems and recharge pathways must be characterized in detail. To this end, water levels and water quality were monitored for 3 years regarding groundwater and adjacent surface-water bodies, at two typical suburban sites in Hanoi. Stable isotope (δ18O, δD of water) analysis and hydrochemical analysis showed that the water from both aquifers and aquitards, including the groundwater obtained from both the monitoring wells and the neighboring household tubewells, was largely derived from evaporation-affected surface-water bodies (e.g., ponds, irrigated farmlands) rather than from rivers. The water-level monitoring results suggested distinct local-scale flow systems for both a Holocene unconfined aquifer (HUA) and Pleistocene confined aquifer (PCA). That is, in the case of the HUA, lateral recharge through the aquifer from neighboring ponds and/or irrigated farmlands appeared to be dominant, rather than recharge by vertical rainwater infiltration. In the case of the PCA, recharge by the above-lying HUA, through areas where the aquitard separating the two aquifers was relatively thin or nonexistent, was suggested. As the decrease in the local surface-water bodies will likely reduce the groundwater recharge, maintaining and enhancing this recharge (through preservation of the surface-water bodies) is considered as essential for the sustainable use of groundwater in the area.

  12. "Rice is essential but tiresome; you should get some noodles": Doi Moi and the political economy of men's extramarital sexual relations and marital HIV risk in Hanoi, Vietnam.

    Science.gov (United States)

    Phinney, Harriet M

    2008-04-01

    Research from around the world has suggested that married women's greatest risk for contracting HIV is from having sexual intercourse with their husbands. On the basis of 6 months of ethnographic research in Hanoi, Vietnam, I argue that the contemporary nature of the HIV epidemic in Hanoi is shaped by 3 interrelated policies implemented in 1986 as part of the government's new economic policy, Doi Moi (Renovation). Together, these policies structure men's opportunities for extramarital sexual relations and encourage wives to acquiesce to their husbands' sexual infidelity, putting both at risk of HIV. I propose 4 structural intervention strategies that address the policies that contribute to men's opportunities for extramarital liaisons and to marital HIV risk.

  13. Analysis of motorcycle fleet in Hanoi for estimation of air pollution emission and climate mitigation co-benefit of technology implementation

    Science.gov (United States)

    Kim Oanh, Nguyen Thi; Thuy Phuong, Mai Thi; Permadi, Didin Agustian

    2012-11-01

    A fleet of over two million motorcycles (MC) in Hanoi is believed to contribute a substantial emission of air pollutants and climate forcers but has not been thoroughly characterized. This study conducted a survey of the MC technologies and activities in Hanoi using questionnaires, GPS monitoring, and video camera in 2008. The data were collected for three typical road types (highways, arterials, residential streets) in 3 zones of the city. Majority of MC in Hanoi were relatively new (3.6 years), had 4-stroke engine, but only 6% was equipped with catalyst exhaust control devices. About 35% of the fleet did not comply with any EURO standards. The MC daily driving was 20 km, mostly done on arterial streets. The main driving features in Hanoi arterials and residential streets were of low speeds with frequent starts/stops and idling. International Vehicle Emissions (IVE) model produced adjusted emission factors (EFs) that were compared with the limited available measurement data. The fleet emission was estimated for 2008 as a base case and for two “what-if” faster technology implementation scenarios: scenario 1 assumed that the entire fleet in 2008 conformed at least EURO2 and scenario 2 assumed 100% MC met the EURO3 standard. Total emissions from the fleet in 2008 of CO, VOC, NOx, SO2, PM10, and CH4 were 158, 51.5, 9.5, 0.17, 2.4 and 9.5 kt, respectively. Emissions of 1,3-butadiene, acetaldehydes, formaldehydes and benzene were 0.26, 1.2, 4.9 and 2.1 kt, respectively. Faster EURO3 technology intrusion in scenario 2 would significantly reduce the emission of pollutants (by 53-94%) and climate forcers in CO2-equivalent (53% for 20-year and 38% for 100-year horizon), which tripled the reductions obtained under scenario 1. Substantial co-benefits for air quality and climate forcer mitigation could be achieved by the faster technology implementation.

  14. Aryl hydrocarbon receptor mediated activities in road dust from a metropolitan area, Hanoi-Vietnam: contribution of polycyclic aromatic hydrocarbons (PAHs) and human risk assessment.

    Science.gov (United States)

    Tuyen, Le Huu; Tue, Nguyen Minh; Suzuki, Go; Misaki, Kentaro; Viet, Pham Hung; Takahashi, Shin; Tanabe, Shinsuke

    2014-09-01

    Dioxin-Responsive Chemical-Activated LUciferase gene eXpression assay (DR-CALUX) was applied to assess the total toxic activity of the mixture of PAHs and related compounds as well as dioxin-related compounds in road dust from urban areas of Hanoi, Vietnam. Road dust from Hanoi contained significantly higher DR-CALUX activities (3 to 39, mean 20 ng CALUX-TEQ/g dw) than those from a rural site (2 to 13, mean 5 ng CALUX-TEQ/g dw). The total concentrations of 24 major PAHs (Σ24PAHs) in urban road dust (0.1 to 5.5, mean 2.5 μg/g dw) were also 6 times higher than those in rural road dust (0.08 to 1.5, mean 0.4 μg/g dw). Diagnostic ratios of PAHs indicated vehicular engine combustion as the major PAH emission source in both sites. PAHs accounted for 0.8 to 60% (mean 10%) and 2 to 76% (mean 20%) of the measured CALUX-TEQs in road dust for Hanoi the rural site, respectively. Benzo[b]-/benzo[k]fluoranthenes were the major TEQ contributors among PAHs, whereas DRCs contributed hydrocarbon receptor agonists in road dust. Significant PAH concentrations in urban dust indicated high mutagenic and carcinogenic potencies. Estimated results of incremental life time cancer risk (ILCR) indicated that Vietnamese populations, especially those in urban areas such as Hanoi, are potentially exposed to high cancer risk via both dust ingestion and dermal contact. This is the first study on the exposure risk of AhR agonists, including PAHs and DRCs, in urban road dust from a developing country using a combined bio-chemical analytical approach. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam

    Directory of Open Access Journals (Sweden)

    Alice M. Tang

    2011-01-01

    Full Text Available We examined clinical and nutritional predictors of weight change over two consecutive 6-month intervals among 99 HIV-positive male injection drug users initiating antiretroviral therapy (ART in Hanoi, Vietnam. The average weight gain was 3.1 ± 4.8 kg in the first six months after ART and 0.8 ± 3.0 kg in the following six months. Predictors of weight change differed by interval. In the first interval, CD4 < 200 cells/μL, excellent/very good adherence to ART, bothersome nausea, and liquid supplement use were all associated with positive weight changes. Moderate to heavy alcohol use and tobacco smoking were associated with negative weight changes. In the second interval, having a CD4 count <200 cells/μL at the beginning of the interval and tobacco smoking were the only significant predictors and both were associated with negative weight changes. We identified several potential areas for interventions to promote weight gain immediately after starting ART in this population. Studies are needed to determine whether improving weight prior to, or at, ART initiation will result in improved outcomes on ART.

  16. Homosexuality-related stigma and sexual risk behaviors among men who have sex with men in Hanoi, Vietnam.

    Science.gov (United States)

    Ha, Huy; Risser, Jan M H; Ross, Michael W; Huynh, Nhung T; Nguyen, Huong T M

    2015-02-01

    This article examined the associations between three forms of homosexuality-related stigma (enacted, perceived, and internalized homosexual stigmas) with risky sexual behaviors, and to describe the mechanisms of these associations, among men who have sex with men (MSM) in Hanoi, Vietnam. We used respondent-driven sampling (RDS) to recruit 451 MSM into a cross-sectional study conducted from August 2010 to January 2011. Data were adjusted for recruitment patterns due to the RDS approach; logistic regression and path analyses were performed. Participants were young and single; most had attended at least some college. Nine out of ten participants engaged in sexual behaviors at moderate to high risk levels. Compared to those who had no enacted homosexual stigma, men having low and high levels of enacted homosexual stigma, respectively, were 2.23 times (95 % CI 1.35-3.69) and 2.20 times (95 % CI 1.04-4.76) more likely to engage in high levels of sexual risk behaviors. In addition, there was an indirect effect of perceived homosexual stigma and internalized homosexual stigma on sexual risk behaviors through depression and drug and alcohol use. Our study provides valuable information to our understanding of homosexual stigma in Vietnam, highlighting the need for provision of coping skills against stigma to the gay community and addressing drinking and drug use among MSM, to improve the current HIV prevention interventions in Vietnam.

  17. The economic burden of pneumonia and meningitis among children less than five years old in Hanoi, Vietnam.

    Science.gov (United States)

    Le, Phuc; Griffiths, Ulla K; Anh, Dang D; Franzini, Luisa; Chan, Wenyaw; Pham, Ha; Swint, John M

    2014-11-01

    To estimate the average treatment costs of pneumonia and meningitis among children under five years of age in a tertiary hospital in Hanoi, Vietnam from societal, health sector and household perspectives. We used a cost-of-illness approach to identify cost categories to be included for different perspectives. A prospective survey was conducted among eligible patients to get detailed personal costing items. From the perspective of the health sector, the mean costs for treating a case of pneumonia and meningitis were USD 180 and USD 300, respectively. From the household's perspective, the average treatment costs were USD 272 for pneumonia and USD 534 for meningitis. When also including indirect costs, the average total treatment costs from the societal perspective were USD 318 for pneumonia and USD 727 for meningitis. The study contributed to limited evidence on the high treatment costs of pneumonia and meningitis to the Vietnamese society, which is useful for a cost-effectiveness analysis of Haemophilus influenzae type b vaccine or other relevant disease preventions. It also indicated a need to re-evaluate the health insurance policy for children under 6 years old, so that the unnecessarily high out-of-pocket costs of these diseases are reduced. © 2014 John Wiley & Sons Ltd.

  18. Element contents and food safety of water spinach (Ipomoea aquatica Forssk.) cultivated with wastewater in Hanoi, Vietnam

    DEFF Research Database (Denmark)

    Marcussen, Helle; Jørgensen, Karin; Holm, Peter E.

    2008-01-01

    Extensive aquatic or semi-aquatic production of water spinach (Ipomoea aquatica Forssk.) for human consumption takes place in Southeast Asia. The aim of this study was to assess the concentrations of 38 elements in soil and water spinach cultivated under different degrees of wastewater exposure...... in Hanoi, Vietnam. The results showed no effect of wastewater use on the overall element concentrations in soil and water spinach. Mean soil concentrations for selected potentially toxic elements at the studied field sites had the following ranges 9.11-18.7 As, 0.333-0.667 Cd, 10.8-14.5 Co, 68-122 Cr, 34...... concentrations in water spinach were 0.139 As, 0.032 Cd, 0.135 Cr, 2.01 Cu, 39.1 Fe, 57.3 Mn, 0.16 Ni, 0.189 Pb and 6.01 Zn mg kg(-1) fresh weight (f.w.). The site and soil content of organic carbon were found to have high influence on the water spinach element concentrations whereas soil pH and the total soil...

  19. The use of technology to find sexual health information online among men who have sex with men in Hanoi, Vietnam, 2016.

    Science.gov (United States)

    Nguyen, Minh X; Krishnan, Aparna; Le, Giang M; Nguyen, Quynh T; Bhadra, Nia M; Nguyen, Sang M; Miller, William C; Go, Vivian F

    2017-01-01

    In an era where mobile phones and computers are ubiquitous, technology-based interventions to reduce HIV and other sexually transmitted infections (STIs) have great potential to reach high-risk groups, including men who have sex with men (MSM). This study aimed to examine technology usage to find sexual health information online among MSM in Hanoi, Vietnam. A cross-sectional study of 205 MSM in Hanoi was conducted from February to May 2016. Overall, 50.7% of participants reported having used a smartphone, computer, or tablet to find HIV/STI testing locations in the past year, and 75.1% reported having used such devices to find other HIV/STI information online. Unemployment (adjusted prevalence ratio [aPR]: 1.13, 95%CI: 1.00-1.28) and having been tested for HIV (aPR: 1.27, 95%CI: 1.07-1.51) were significantly associated with using technology to find online sexual health information. MSM who had ever exchanged sex for money or drugs (aPR: 0.80; 95%CI: 0.68-0.94) were less likely to use technology to find sexual health information online. Technology is a promising platform for HIV/STI prevention programs among MSM, with the potential to reach different subgroups. Further efforts to develop technology-based interventions tailored to the needs of the MSM communities in Hanoi and to encourage MSM who were not currently seeking sexual health information and testing services online to do so are necessary.

  20. Assessment of injection safety in Ha Dong General Hospital, Hanoi, in 2012 [version 3; referees: 2 approved

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    Phan Van Tuong

    2017-09-01

    Full Text Available Background: Injection is one of the most frequently used medical methods to introduce drugs or other substances into the body for purposes of treatment or prevention. Unsafe injection can cause adverse outcomes, such as abscess and anaphylactic shock, and increases the risk of blood-borne transmission of viruses to patients and health care workers, as well as the community. Recognizing the importance of injection safety, in 2000 the Vietnamese Ministry of Health (MOH collaborated with the Vietnam Nurses Association to launch the “Safe injection” program throughout the country, including Hanoi. Methods: This cross-sectional study, combining quantitative and qualitative analysis, was conducted from February to August 2012 in Ha Dong General Hospital using a structured questionnaire and observation checklist. The target population of the study was 109 nurses working in clinical departments and 436 injections were observed. Results: The percentage of nurses who are familiar with injection safety standards was found to be 82.6%. The proportion of practical injections that met the 23 standards of injection safety set by the MOH amounted to 22.2%. The factors related to safe injection practice of nurses who are younger age group (OR=3.1; p<0.05 and lower amount of working years (OR=2.8; p<0.05. Conclusions: Despite the high level of knowledge about safety injection, a low proportion of nurses performed correct safety injection practice. Moreover, the results demonstrated that experience might not always guarantee better practice. The findings raise the need for further training about this issue, especially among older nurses.

  1. Helminth infections among people using wastewater and human excreta in peri-urban agriculture and aquaculture in Hanoi, Vietnam.

    Science.gov (United States)

    Do, Thuy Trang; Mølbak, Kåre; Phung, Dac Cam; Dalsgaard, Anders

    2007-12-01

    To assess the prevalence of helminth infections and their associated risks in a community using both wastewater and human excreta in agriculture and aquaculture. A cross-sectional study was conducted in a peri-urban area in Hanoi, Vietnam. Data on the demography, socioeconomics and sanitation were collected from a survey of 400 agricultural households. Parasitological examination for the eggs of Ascaris sp., Trichuris sp. and hookworm was performed on single stool specimens obtained from study household members' 15-70 years and 0-72 months of age. Of 807 stool samples collected from 620 adults and 187 children, 39% were infected with helminths. The prevalence of infections with Ascaris sp., Trichuris sp. and hookworm was 21.6%, 9.8% and 21.8%, respectively. Univariate and multivariate analyses showed that being an adult, female gender, living in a household without a latrine, excreta composted for less than 1 month and use of fresh human excreta were significantly associated with co-infection with all three helminths. Being an adult was an independent determinant for infections with individual helminths. The absence of a latrine and use of stored urine for irrigation were associated with an increased risk of Ascaris infection. Risk factors for Trichuris infection were inadequately composted excreta and year-round wastewater contact; risk factors for hookworm infection were female gender, household without a latrine and use of fresh human excreta. Wastewater exposure did not pose a major risk for helminth infection in this community. Instead, lack of sanitation facilities and use of fresh or inadequately composted human excreta in agriculture were important risk factors.

  2. Element contents and food safety of water spinach (Ipomoea aquatica Forssk.) cultivated with wastewater in Hanoi, Vietnam.

    Science.gov (United States)

    Marcussen, Helle; Joergensen, Karin; Holm, Peter E; Brocca, Daniela; Simmons, Robert W; Dalsgaard, Anders

    2008-04-01

    Extensive aquatic or semi-aquatic production of water spinach (Ipomoea aquatica Forssk.) for human consumption takes place in Southeast Asia. The aim of this study was to assess the concentrations of 38 elements in soil and water spinach cultivated under different degrees of wastewater exposure in Hanoi, Vietnam. The results showed no effect of wastewater use on the overall element concentrations in soil and water spinach. Mean soil concentrations for selected potentially toxic elements at the studied field sites had the following ranges 9.11-18.7 As, 0.333-0.667 Cd, 10.8-14.5 Co, 68-122 Cr, 34.0-62.1 Cu, 29.9-52.8 Ni, 32.5-67.4 Pb, 0.578-0.765 Tl and 99-189 Zn mg kg(-1) dry weight (d.w.). In all samples Cd, Pb and Zn soil concentrations were below the Vietnamese Guideline Values (TCVN 7209-2002) for agricultural soils whereas As and Cu exceeded the guideline values. Maximum site element concentrations in water spinach were 0.139 As, 0.032 Cd, 0.135 Cr, 2.01 Cu, 39.1 Fe, 57.3 Mn, 0.16 Ni, 0.189 Pb and 6.01 Zn mg kg(-1) fresh weight (f.w.). The site and soil content of organic carbon were found to have high influence on the water spinach element concentrations whereas soil pH and the total soil element concentrations were of less importance. The estimated average daily intake of As, Cd, Cu, Fe, Pb and Zn for adult Vietnamese consumers amounts to <11% of the maximum tolerable intake proposed by FAO/WHO for each element. It is assessed that the occurrence of the investigated elements in water spinach will pose low health risk for the consumers.

  3. Knowledge, Attitude, Frequency and Level of Consumption Regarding Non-alcoholic Carbonated Soft Drinks among Students from Two High Schools in Hanoi, Vietnam in 2015

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    Nguyen Thanh Ha

    2017-02-01

    Full Text Available Objective: This article aims to describe the knowledge, attitude, frequency and level of consumption regarding non-alcoholic carbonated soft drinks (NCSD among students from two high schools in Hanoi. Materials and Methods: A cross-sectional survey including a semi-quantitative food frequency were conducted with 620 students from two high schools, one in the urban area and the other in the rural area of Hanoi city. Results: Data on knowledge of health risk associated with the consumption of NCSD showed neagtive results (only 11.9% of the students were able to identify all the contents of NCSD correctly, and 2.7% knew all eight health risks due to consumption of NCSD. Besides, 31.4% of all students did not have the intention to quit NCSD despite being aware of health risks associated with the consumption of NCSD. Students who reported consuming NCSD within one month prior to the study constituted 83.1%, and those who consumed NCSD 1–2 times/week accounted for the highest proportion, being 21.3%. On average, each student consumed 2,094 ml NCSD within one month prior to the study. Suburban students and male students consumed more than urban and female ones, respectively (p < 0.01. Recommendations: Students should be equipped with information about NCSD related health risks and encouraged to consume less NCSD.

  4. Barriers to access and uptake of antiretroviral therapy among HIV-positive men who have sex with men in Hanoi, Vietnam: from HIV testing to treatment.

    Science.gov (United States)

    Bui, Hao T M; Le, Giang M; Mai, Anh Q; Zablotska-Manos, Iryna; Maher, Lisa

    2017-08-01

    Little is known about the experiences of Vietnamese men who have sex with men in accessing HIV testing and treatment. We aimed to explore barriers to access and uptake of antiretroviral therapy (ART) among HIV-positive men who have sex with men in Hanoi. During 2015, we conducted qualitative interviews with 35 participants recruited using snowball sampling based on previous research and social networks. Key individual impediments to ART uptake included inadequate preparation for a positive diagnosis and the dual stigmatisation of homosexuality and HIV and its consequences, leading to fear of disclosure of HIV status. Health system barriers included lack of clarity and consistency about how to register for and access ART, failure to protect patient confidentiality and a reticence by providers to discuss sexual identity and same-sex issues. Results suggest fundamental problems in the way HIV testing is currently delivered in Hanoi, including a lack of client-centred counselling, peer support and clear referral pathways. Overcoming these barriers will require educating men who have sex with men about the benefits of routine testing, improving access to quality diagnostic services and building a safe, confidential treatment environment for HIV-positive men to access, receive and remain in care.

  5. TerraSAR-X Data for High-Precision Land Subsidence Monitoring: A Case Study in the Historical Centre of Hanoi, Vietnam

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    Tuan S. Le

    2016-04-01

    Full Text Available In this study, subsidence patterns in the Historical Centre of Hanoi, Vietnam are mapped using the Interferometric Synthetic Aperture Radar (InSAR technique, with particular emphasis on the stability of ancient monuments, historical buildings and archaeological sectors. Due to the small and scattered characteristics of these structures, not only is a comprehensive coverage of radar targets needed, but also the details of a single building or monument. We took advantage of the high-resolution TerraSAR-X imagery with the aid of oversampling implementation on the Small Baseline (SB InSAR approach to reveal the subsidence patterns. A total of 6.29 million radar targets were obtained, maintaining the average density of 217,012 points/km2. Our results suggest that image oversampling not only increased the number of measurement points 4.4 times more than the standard processing chain, but also removed some of the noisiest points. The observed subsidence patterns are mostly related to adjacent groundwater extraction and construction activities, with maximum subsiding rate reaching −18.1 mm/year for the study period April 2012 to November 2013. Generally, heritage assets and monuments in the Citadel, the Old Quarter and French Quarter remain in a steady state, whereas those located along the Red River and in southern Hanoi are subject to subsidence.

  6. Microbial contamination along the main open wastewater and storm water channel of Hanoi, Vietnam, and potential health risks for urban farmers.

    Science.gov (United States)

    Fuhrimann, Samuel; Pham-Duc, Phuc; Cissé, Guéladio; Tram, Nguyen Thuy; Thu Ha, Hoang; Dung, Do Trung; Ngoc, Pham; Nguyen-Viet, Hung; Anh Vuong, Tuan; Utzinger, Jürg; Schindler, Christian; Winkler, Mirko S

    2016-10-01

    The use of wastewater in agriculture and aquaculture has a long tradition throughout Asia. For example, in Hanoi, it creates important livelihood opportunities for >500,000 farmers in peri-urban communities. Discharge of domestic effluents pollute the water streams with potential pathogenic organisms posing a public health threat to farmers and consumers of wastewater-fed foodstuff. We determined the effectiveness of Hanoi's wastewater conveyance system, placing particular emphasis on the quality of wastewater used in agriculture and aquaculture. Between April and June 2014, a total of 216 water samples were obtained from 24 sampling points and the concentrations of total coliforms (TC), Escherichia coli, Salmonella spp. and helminth eggs determined. Despite applied wastewater treatment, agricultural field irrigation water was heavily contaminated with TC (1.3×10(7)colony forming unit (CFU)/100mL), E. coli (1.1×10(6)CFU/100mL) and Salmonella spp. (108 most probable number (MPN)/100mL). These values are 110-fold above Vietnamese discharge limits for restricted agriculture and 260-fold above the World Health Organization (WHO)'s tolerable safety limits for unrestricted agriculture. Mean helminth egg concentrations were below WHO tolerable levels in all study systems (pollution, halving the proportion of untreated wastewater and increasing recycling and safe reuse globally. Copyright © 2016. Published by Elsevier B.V.

  7. Láser de dióxido de carbono fraccionado asociado a corticoide tópico para el tratamiento del prurito en las secuelas cicatriciales del paciente quemado

    Directory of Open Access Journals (Sweden)

    Sara A. González-Porto

    Full Text Available El prurito en los pacientes quemados supone una secuela frecuente que puede ser incapacitante y difícilmente controlable mediante tratamiento médico. Presentamos el caso de un paciente con prurito grave resistente a tratamiento médico y los resultados tras el tratamiento con láser ablativo y liberación de corticoide local asistida por láser. Se trata de un paciente con quemaduras graves en el 70% de superficie corporal, con prurito refractario a tratamiento médico y lesiones por rascado que precisaron de sedorrelajación e intubación orotraqueal, y en el que realizamos una sola sesión de tratamiento con láser CO² fraccionado tras la que se aplicó cura oclusiva con triamcinolona acetónido disuelta en suero (20 mg/ml. La evaluación del resultado se realizó mediante valoración del prurito (escala Burn Itch Questionnaire y del resultado clínico y estético de la cicatriz (escalas Vancouver Scar Scale y Patient and Observer Scar Assessment Scale. Logramos un buen control del prurito y de las lesiones por rascado sin complicaciones asociadas. La liberación de fármacos asistida por láser fue la base del nuestro tratamiento, en el que el láser ablativo crea canales de comunicación transepidérmicos que favorecen la entrada del corticoide a la dermis y el efecto inmediato del mismo. Esta modalidad de tratamiento y este nuevo concepto clínico se presentan como una alternativa terapéutica importante en el tratamiento del prurito refractario en el paciente quemado.

  8. High HIV Prevalence and Risk Among Male Clients of Female Sex Workers in Hanoi and Ho Chi Minh City, Vietnam.

    Science.gov (United States)

    Nadol, Patrick; Hoang, Tran Vu; Le, Linh-Vi; Nguyen, Tuan Anh; Kaldor, John; Law, Matthew

    2017-08-01

    In Vietnam's concentrated HIV epidemic, female sex workers (FSWs) are at increased risk for acquiring and transmitting HIV, largely through their male clients. A high proportion of males in Vietnam report being clients of FSWs. Studying HIV-related risk factors and prevalence among male clients is important, particularly given the potential for male clients to be a 'bridge' of HIV transmission to the more general population or to sex workers. Time-location sampling was used to identify FSW in Hanoi and Ho Chi Minh City, Vietnam's largest cities, in 2013-2014. Recruited FSWs were asked to refer one male client to the study. Demographic and risk behavior data were collected from FSWs and male clients by administered questionnaires. Biologic specimens collected from male clients were tested for HIV and opiates. Sampling weights, calculated based on the FSWs probability of being selected for enrolment, were applied to prevalence estimates for both FSWs and male clients. Logistic regression models were developed to obtain odds ratios for HIV infection among male clients. A total of 804 male clients were enrolled. Overall, HIV prevalence among male clients was 10.2%; HIV prevalence was 20.7% (95% confidence interval (CI) 15.0-27.9%) among those reporting a history of illegal drug use and 32.4% (95% CI 20.2-47.7%) among those with opioids detected in urine. HIV prevalence among male clients did not differ across 'bridging' categories defined by condom use with FSWs and regular partners over the previous 6 months. HIV among male clients was associated with a reported history of illegal drug use (OR 3.76; 95% CI 1.87-7.56), current opioid use (OR 2.55; 95% CI 1.02-6.36), and being referred by an FSW who self-reported as HIV-positive (OR 5.37; 95% CI 1.46-19.75). Self-reported HIV prevalence among enrolled FSWs was 2.8%. Based on HIV test results of male clients and self-reported status from FSWs, an estimated 12.1% of male client-FSW pairs were sero-discordant. These

  9. Physical growth during the first year of life. A longitudinal study in rural and urban areas of Hanoi, Vietnam.

    Science.gov (United States)

    Nguyen, Huong Thu; Eriksson, Bo; Nguyen, Liem Thanh; Nguyen, Chuc Thi Kim; Petzold, Max; Bondjers, Göran; Ascher, Henry

    2012-03-12

    Good infant growth is important for future health. Assessing growth is common in pediatric care all over the world, both at the population and individual level. There are few studies of birth weight and growth studies comparing urban and rural communities in Vietnam. The first aim is to describe and compare the birth weight distributions and physical growth (weight and length) of children during their first year in one rural and one urban area of Hanoi Vietnam. The second aim is to study associations between the anthropometric outcomes and indicators of the economic and educational situations. Totally 1,466 children, born from 1st March, 2009 to June 2010, were followed monthly from birth to 12 months of age in two Health and Demographic Surveillance Sites; one rural and one urban. In all, 14,199 measurements each of weight and length were made. Birth weight was recorded separately. Information about demographic conditions, education, occupation and economic conditions of persons and households was obtained from household surveys. Fractional Polynomial models and standard statistical methods were used for description and analysis. Urban infants have higher birth weight and gain weight faster than rural infants. The mean birth weight for urban boys and girls were 3,298 grams and 3,203 grams as compared to 3,105 grams and 3,057 grams for rural children. At 90 days, the urban boys were estimated to be 4.1% heavier than rural boys. This difference increased to 7.2% at 360 days. The corresponding difference for girls was 3.4% and 10.5%. The differences for length were comparatively smaller. Both birth weight and growth were statistically significantly and positively associated with economic conditions and mother education. Birth weight was lower and the growth, weight and length, considerably slower in the rural area, for boys as well as for girls. The results support the hypothesis that the rather drastic differences in maternal education and economic conditions lead

  10. Studying the effectiveness of activated carbon R95 respirators in reducing the inhalation of combustion by-products in Hanoi, Vietnam: a demonstration study

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    Wertheim Heiman FL

    2012-09-01

    Full Text Available Abstract Background Urban air pollution is an increasing health problem, particularly in Asia, where the combustion of fossil fuels has increased rapidly as a result of industrialization and socio-economic development. The adverse health impacts of urban air pollution are well established, but less is known about effective intervention strategies. In this demonstration study we set out to establish methods to assess whether wearing an R95 activated carbon respirator could reduce intake of polycyclic aromatic hydrocarbons (PAH in street workers in Hanoi, Vietnam. Methods In this demonstration study we performed a cross-over study in which non-smoking participants that worked at least 4 hours per day on the street in Hanoi were randomly allocated to specific respirator wearing sequences for a duration of 2 weeks. Urines were collected after each period, i.e. twice per week, at the end of the working day to measure hydroxy PAHs (OH-PAH using gas chromatography/high resolution mass spectrometry. The primary endpoint was the urinary concentration of 1-hydroxypyrene (1-OHP. Results Forty-four participants (54.5% male, median age 40 years were enrolled with the majority being motorbike taxi drivers (38.6% or street vendors (34.1%. The baseline creatinine corrected urinary level for 1-OHP was much higher than other international comparisons: 1020 ng/g creatinine (IQR: 604–1551. Wearing a R95 mask had no significant effect on 1-OHP levels: estimated multiplicative effect 1.0 (95% CI: 0.92-1.09 or other OH-PAHs, except 1-hydroxynaphthalene (1-OHN: 0.86 (95% CI: 0.11-0.96. Conclusions High levels of urine OH-PAHs were found in Hanoi street workers. No effect was seen on urine OH-PAH levels by wearing R95 particulate respirators in an area of high urban air pollution, except for 1-OHN. A lack of effect may be de to gaseous phase PAHs that were not filtered efficiently by the respirator. The high levels of urinary OH-PAHs found, urges for effective

  11. Microbial contamination along the main open wastewater and storm water channel of Hanoi, Vietnam, and potential health risks for urban farmers

    Energy Technology Data Exchange (ETDEWEB)

    Fuhrimann, Samuel, E-mail: samuel.fuhrimann@unibas.ch [Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel (Switzerland); University of Basel, Basel (Switzerland); Pham-Duc, Phuc [Center for Public Health and Ecosystem Research, Hanoi School of Public Health, Hanoi (Viet Nam); Cissé, Guéladio [Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel (Switzerland); University of Basel, Basel (Switzerland); Tram, Nguyen Thuy; Thu Ha, Hoang [Department of Microbiology, National Institute of Hygiene and Epidemiology, Hanoi (Viet Nam); Dung, Do Trung [Department of Parasitology, National Institute of Malaria, Parasitology, and Entomology, Hanoi (Viet Nam); Ngoc, Pham [Department of Animal Hygiene, National Institute for Veterinary Research, Hanoi (Viet Nam); Nguyen-Viet, Hung [Center for Public Health and Ecosystem Research, Hanoi School of Public Health, Hanoi (Viet Nam); International Livestock Research Institute, Hanoi (Viet Nam); Anh Vuong, Tuan [Department of Microbiology, National Institute of Hygiene and Epidemiology, Hanoi (Viet Nam); Utzinger, Jürg; Schindler, Christian; Winkler, Mirko S. [Department of Epidemiology and Public Health, Swiss Tropical and Public Health Institute, Basel (Switzerland); University of Basel, Basel (Switzerland)

    2016-10-01

    The use of wastewater in agriculture and aquaculture has a long tradition throughout Asia. For example, in Hanoi, it creates important livelihood opportunities for > 500,000 farmers in peri-urban communities. Discharge of domestic effluents pollute the water streams with potential pathogenic organisms posing a public health threat to farmers and consumers of wastewater-fed foodstuff. We determined the effectiveness of Hanoi's wastewater conveyance system, placing particular emphasis on the quality of wastewater used in agriculture and aquaculture. Between April and June 2014, a total of 216 water samples were obtained from 24 sampling points and the concentrations of total coliforms (TC), Escherichia coli, Salmonella spp. and helminth eggs determined. Despite applied wastewater treatment, agricultural field irrigation water was heavily contaminated with TC (1.3 × 10{sup 7} colony forming unit (CFU)/100 mL), E. coli (1.1 × 10{sup 6} CFU/100 mL) and Salmonella spp. (108 most probable number (MPN)/100 mL). These values are 110-fold above Vietnamese discharge limits for restricted agriculture and 260-fold above the World Health Organization (WHO)'s tolerable safety limits for unrestricted agriculture. Mean helminth egg concentrations were below WHO tolerable levels in all study systems (< 1 egg/L). Hence, elevated levels of bacterial contamination, but not helminth infections, pose a major health risk for farmers and consumers of wastewater fed-products. We propose a set of control measures that might protect the health of exposed population groups without compromising current urban farming activities. This study presents an important example for sanitation safety planning in a rapidly expanding Asian city and can guide public and private entities working towards Sustainable Development Goal target 6.3, that is to improve water quality by reducing pollution, halving the proportion of untreated wastewater and increasing recycling and safe reuse globally

  12. Virtual nursing grand rounds and shared governance: how innovation and empowerment are transforming nursing practice at Thanh Nhan Hospital, Hanoi, Vietnam.

    Science.gov (United States)

    Crow, Gregory L; Nguyen, Thanh; DeBourgh, Gregory A

    2014-01-01

    The Vietnam Nurse Project has been operating in Hanoi since 2007. Its primary purpose is to improve nursing education through curriculum development, faculty development, and the introduction of a more student-centric teaching and learning environment. The Virtual Nursing Grand Rounds component of the project is an academic-practice partnership between the Vietnam Nurse Project at the University of San Francisco School of Nursing and Health Professions and the Thanh Nhan Hospital intensive care unit. Its goal is to improve nursing practice in the Thanh Nhan Hospital intensive care unit. The Virtual Nursing Grand Rounds is a fully interactive real-time synchronous computer technology-assisted point-to-point program that provides ongoing evidence-based staff development and consultative services.

  13. Le renouveau des lentilles d’eau : de la prostitution à Hanoi à la toute fin du xxe siècle

    OpenAIRE

    Le Failler, Philippe

    2017-01-01

    Quoiqu’interdite, la prostitution est largement répandue au Vietnam. Quasi absente pendant la fermeture du pays qui s’étend de 1975 à 1986, cette pratique y est revenue en force à la faveur de l’ouverture du pays, lorsque le carcan social s’est desserré induisant une liberté de mouvement et une adaptation plus ou moins réussie à l’économie de marché. Bien que le phénomène ait été plus aisément perceptible à Saigon, Hanoi ne faisait pas exception. Les lignes suivantes résultent d’une enquête i...

  14. Measurement of Stigma in Men Who Have Sex with Men in Hanoi, Vietnam: Assessment of a Homosexuality-Related Stigma Scale

    Directory of Open Access Journals (Sweden)

    Huy Ha

    2013-01-01

    Full Text Available Objective. To develop and assess a homosexuality-related stigma scale among men who have sex with men (MSM in Hanoi, Vietnam. Methods. We conducted a cross-sectional study using respondent-driven sampling in Hanoi, Vietnam, in 2011. We used a cross-validation approach. Factor analysis was performed, and interitem correlation matrices were constructed to identify the latent factor structures, examine the goodness of fit, and assess convergent and discriminant validity of the determined scales. Internal consistency checks were performed in split samples and whole sample, and separately for each determined factor. Results. The findings were consistent in split samples. Three homosexuality-related stigma factors were identified: enacted homosexual stigma, perceived homosexual stigma, and internalized homosexual stigma. The fit indices of the confirmatory factor analysis in both split samples supported the hypothesized three-factor structures (in subsamples A and B: χ2/degrees of freedom ratio = 1.77 and 1.59, nonnormed fit index = 0.92 and 0.94, comparative fit index = 0.93 and 0.95, and the root mean square of approximation = 0.06 and 0.05, resp.. The interitem correlation supported the convergent and discriminant validity of the scales. The reliability of the three scales indicated good consistency (Cronbach’s alpha: 0.79–0.84 across split samples and for the whole data. Conclusion. Our scales have good psychometric properties for measuring homosexuality-related stigma. These comprehensive and practical tools are crucial not only to assess stigma against MSM and its consequence, but also to guide the development of interventions targeting MSM, as well as to evaluate the efficacy of existing stigma reduction efforts in Vietnam and other countries with similar settings.

  15. Social marketing of low dead space syringes in Vietnam: findings from a 1-year pilot program in Hanoi, Thai Nguyen, and Ho Chi Minh City.

    Science.gov (United States)

    Huong, Ngo Thi Thanh; Mundy, Gary; Neukom, Josselyn; Zule, William; Tuan, Nguyen Minh; Tam, Nguyen Minh

    2015-05-30

    Although a growing body of evidence suggests that low dead space syringes may reduce the risk of human immunodeficiency virus (HIV) and Hepatitis C virus infection associated with sharing syringes among people who inject drugs, there is little evidence of effective approaches to motivate people who inject drugs (PWID) to shift from high to low dead space syringes. Using a mix of consumer and trade marketing approaches, informed by rapid assessments of both the syringe market and PWID preferences, practices, and behaviors in Hanoi and Ho Chi Minh City, Population Services International (PSI) Vietnam piloted an intervention to increase the use of low dead space syringes (LDSS) in the three provinces of Hanoi, Ho Chi Minh City, and Thai Nguyen, where an estimated 31% of PWID are HIV positive and 58% are living with hepatitis C virus (HCV). This paper provides a summary of the social marketing activities implemented and results achieved by PSI Vietnam during an initial 1-year pilot period from December 2012 to December 2013 in these three provinces to explore their effectiveness in motivating PWID to use low dead space syringes. We found major increases in sales of LDSS accompanied by increases in reported use and consistent use of LDSS among PWID in the three provinces included in the pilot program and a positive and independent association (odds ratio (OR) 21.08; 95% confidence interval (CI) 10.6-27.3) between LDSS use and exposure to social marketing activities. We also found that LDSS use had a stronger association with perceptions of LDSS product quality than with perceptions regarding LDSS potential to reduce HIV transmission risk and use. We conclude that social marketing interventions have an important role to play in widening access to and the use of LDSS for PWID, as they address the need for PWID to find LDSS when and where they need them and also promote the benefits of LDSS use to PWID. High coverage of these activities among PWID appears to be the key in

  16. Leishmaniosis laríngea recidivante: un caso inusual en un paciente inmunocompetente tratado con corticoides Recidivant laryngeal leishmaniosis: an unusual case in an immunocompetent patient treated with corticosteroids

    Directory of Open Access Journals (Sweden)

    R. Casero

    2010-06-01

    Full Text Available La leishmaniosis es una parasitosis de evolución crónica; en Argentina, sus agentes etiológicos principales pertenecen al complejo Leishmania (Viannia braziliensis, habitualmente asociado a lesiones cutáneas y mucocutáneas. Informamos en este trabajo un caso de leishmaniosis laríngea en un hombre de 29 años procedente de Jujuy, quien a raíz de múltiples subdiagnósticos portaba esta parasitosis desde hacía 20 años. En el año 2008 este paciente consulta por disfonía crónica y trastornos en las vías aéreas superiores, refiere que fue sometido a terapias con tuberculostáticos, antifúngicos y corticoides desde 2002. Diferentes biopsias y fibroscopías revelaron los siguientes diagnósticos: laringitis granulomatosa inespecífica, laringitis compatible con tuberculosis, laringitis compatible con histoplasmosis, linfoma Natural Killer extraganglionar a células pequeñas. Finalmente, estudios realizados en nuestro hospital demostraron la presencia de una laringe granulomatosa en toda su extensión, amastigotes intra y extracelulares de Leishmania spp., ausencia de formas compatibles con Micobacterias e Histoplasma, y laringitis crónica vinculable a Leishmania spp. El paciente realizó tratamiento con antimoniato de N-metil-glucamina y demostró una muy buena evolución clínica tras ser examinado 2 meses después. Si bien la leishmaniosis laríngea como lesión única no es la presentación prevalente de esta zoonosis, su estudio amerita especial atención en pacientes tratados con corticoides, pues esto evitará un diagnóstico tardío y las mayores consecuencias asociadas a la morbimortalidad propia de esta parasitosis.Leishmaniosis is a chronic parasitic disease, which in Argentina is mainly caused by protozoa belonging to the Leishmania (Viannia braziliensis complex, leading to cutaneous and mucosal pathologies. We report a rare case of laryngeal leishmaniosis in a 29 year-old man from Jujuy province, Argentina, who had been

  17. Baja frecuencia de prescripción de profilaxis para osteoporosis en pacientes en tratamiento crónico con corticoides en Colombia Low frequency of prophylaxis prescription for osteoporosis in patients receiving chronic treatment with corticosteroids in Colombia

    Directory of Open Access Journals (Sweden)

    Jorge Machado-Alba

    2013-03-01

    Full Text Available Objetivos. Identificar la frecuencia de uso de medicamentos para prevención de osteoporosis inducida por corticoides (OIC en pacientes que reciben corticoides por un periodo mayor a tres meses y que son afiliados al Sistema General de Seguridad Social en Salud de Colombia. Materiales y métodos. Estudio de tipo transversal. Se utilizó información sobre, las personas afiliadas al Sistema General de Seguridad Social en Salud de Colombia (3,7 millones. Se incluyeron en el trabajo los usuarios de todas las edades y sexos a los cuales se les indicó algún glucocorticoide entre el 1 de agosto y 30 de noviembre de 2011.Se identificaron variables sociodemográficas y las características de prescripción de glucocorticoides y medicamentos para profilaxis de OIC con dosis expresadas en dosis diarias definidas (DDD. Resultados. Se obtuvo una base de datos de 255 568 prescripciones de glucocorticoides, de los cuales 1837 pacientes recibían algún glucocorticoide de manera crónica. Predominaron pacientes de sexo femenino (60,2%, edad promedio de 55,2± 16,9 años distribuidos en 65 ciudades del país. El glucocorticoide más utilizado fue prednisolona en 1546 (84,1%, mientras que el medicamento para profilaxis más prescrito fue calcitriol (67,1%. Se encontraron 994 casos (54,2% que no estaban recibiendo profilaxis para osteoporosis a pesar de requerirlo. Conclusiones. Existe un bajo empleo de profilaxis para OIC. Se recomienda implementar acciones de farmacovigilancia que permitan identificar problemas relacionados con medicamentos para prevenir eventos adversos y optimizar recursos, anticipándose a la aparición de complicaciones para el pacienteObjective. To identify the frequency of drug use for the prevention of corticosteroid induced osteoporosis (CIO among patients using corticosteroids for more than three months affiliated to the General Social Health Security System of Colombia. Materials and methods. Cross-sectional study. Information about

  18. Evaluation of insulin-like growth factor-1, total thyroxine, feline pancreas-specific lipase and urinary corticoid-to-creatinine ratio in cats with diabetes mellitus in Switzerland and the Netherlands.

    Science.gov (United States)

    Schaefer, Sandra; Kooistra, Hans S; Riond, Barbara; Suchodolski, Jan S; Steiner, Jörg M; Prins, Marrit; Zini, Eric; Reusch, Claudia E

    2017-08-01

    Objectives The aim of the study was to evaluate circulating insulin-like growth factor-1 (IGF-1), feline pancreas-specific lipase (fPLI) and total thyroxine (TT4) concentrations and urinary corticoid-to-creatinine ratio (UCCR) as indicators for the prevalence of acromegaly, pancreatitis, hyperthyroidism and hypercortisolism in cats with diabetes mellitus. Methods Blood and urine samples were collected from diabetic cats treated in primary care clinics in Switzerland and the Netherlands. Standardised questionnaires and physical examination forms provided clinical information from owners and veterinarians. Laboratory testing included serum biochemistry profile analysis and measurement of circulating fructosamine, IGF-1, fPLI, and TT4 concentrations and UCCR. CT of the pituitary gland was performed using a multidetector computed tomography scanner. Results Blood samples were available from 215 cats and urine samples were collected at home from 117 cats. Age ranged from 2-18 years (median 12 years) and body weight from 2.7-12.3 kg (median 5.5 kg). Sixty-five percent of the cats were castrated male and 35% were female (33% spayed); 82% were domestic shorthair cats. Eighty percent of cats received a porcine insulin zinc suspension, 19.5% insulin glargine and 0.5% a human neutral protamine hagedorn insulin. Thirty-six of 202 (17.8%) cats had IGF-1 concentrations >1000 ng/ml. Serum fPLI, and TT4 concentrations and UCCR were increased in 86/196 (43.9%), 9/201 (4.5%) and 18/117 cats (15.3%), respectively. Prevalence did not differ between countries. Conclusions Hyperthyroidism is rare, whereas increased fPLI concentration, possibly reflecting pancreatitis, is common in diabetic cats. The high UCCR may reflect activation of the hypothalamus-pituitary-adrenal axis, which also occurs in diabetic humans. The percentage of cats with increased IGF-1 was high but lower than reported in recent studies.

  19. Uso de corticóide como inibidor da resposta inflamatória sistêmica induzida pela circulação extracorpórea Corticoid as an inhibitor of systemic inflammatory response, induced by cardiopulmonary bypass

    Directory of Open Access Journals (Sweden)

    Luiz Antonio BRASIL

    1999-07-01

    diferença estatisticamente significativa entre os dois grupos. CONCLUSÕES: A metilprednisolona inibiu significantemente a liberação de citocinas pró-inflamatórias principalmente o TNFa. Os efeitos sistêmicos adversos decorrentes da reação inflamatória pós-CEC foram atenuados com o uso do corticóide.Cardiopulmonary bypass (CPB induces the development of a systemic inflammatory response syndrome, with the release of cytokines that are responsible for many clinical manifestations. PURPOSE: The purpose of the study was to observe the release of the cytokines - tumor necrosis factor alpha (TNFa and Interleukine-6 (IL-6, and to verify the clinical alterations produced in patients undergoing myocardial revascularization with CPB, with or without corticoids. MATERIAL AND METHODS: Thirty patients were studied - 15 used corticoid (methylprednisolone, 30 mg/kg -Group I and 15 did not (Group II. Serial blood samples were collected and the TNFa and IL-6 release were analyzed, as well as the leukocyte count, erythrocyte sedimentation rate and glycemia. The blood pressure, cardiac rate, temperature, postoperative bleeding, orotracheal tubing time and inotropic drug requirement were also compared. Statistical significance was assumed when p £ 0.05. RESULTS: In Group I TNFa was not detected and IL-6 was detected in 13 patients, with levels ranging from 8.6 to 101.8 pg/ml. In Group II TNFa was detected in 13 patients, with levels between 5.4 and 231.0 pg/ml. The IL-6 in this group was detected in 15 patients, with higher levels than those in Group I, varying between 5.5 and 2569.0 pg/ml. The Group I patients had higher medium blood pressure (7.9 ± 0.5 vs 7.3 ± 0.4 mmHg and lower inotropic drug requirement (5 vs 11. They evolved with less tachycardia (105.6 ± 5.9 vs 109.3 ± 7.2 bpm, lower temperature (36.5 ± 0.2 vs 37.3 ± 0.2°C, lower postoperative bleeding, (576.6 ± 119.5 vs 810.0 ± 176.2 ml, shorter orotracheal tubing time (11.0 ± 2.0 vs 14.6 ± 2.9 hs and lower

  20. Knowledge of HIV and factors associated with attitudes towards HIV among final-year medical students at Hanoi medical university in Vietnam.

    Science.gov (United States)

    Platten, Michael; Pham, Ha N; Nguyen, Huy V; Nguyen, Nhu T; Le, Giang M

    2014-03-20

    The success of HIV care strongly depends upon skills of the healthcare worker. Vietnam has a punitive history towards HIV and even though this has changed recently, persons living with HIV are still facing discrimination. The objective of this paper is to assess the gaps in knowledge of HIV and factors associated with discriminatory attitudes towards persons living with HIV among medical students in order to improve medical training. In a cross-sectional quantitative study using a structured questionnaire, 200 final-year medical students at Hanoi Medical University were approached for data collection in May of 2012. Descriptive statistics (percentages) were used to present four HIV knowledge tests. Linear regression models were examined to highlight factors that are associated with general attitudes towards HIV and attitudes towards HIV in a clinical setting. Although students performed overall well in the knowledge category of HIV discrimination and stigma, there were several gaps in knowledge of HIV, including the categories of HIV-related basic sciences, prevention, and care and treatment. Knowledge of stigma and discrimination was a significant positive predictor of General non-prejudicial attitude to HIV and AIDS (β=0.186, Pstudents. As persons who inject drugs carry a proportionately high burden of HIV in Vietnam, it is also important to include methadone training for students.

  1. Microbiological quality of fish grown in wastewater-fed and non-wastewater-fed fishponds in Hanoi, Vietnam: influence of hygiene practices in local retail markets.

    Science.gov (United States)

    Lan, Nguyen Thi Phong; Dalsgaard, Anders; Cam, Phung Dac; Mara, Duncan

    2007-06-01

    Mean water quality in two wastewater-fed ponds and one non-wastewater-fed pond in Hanoi, Vietnam was approximately 10(6) and approximately 10(4) presumptive thermotolerant coliforms (pThC) per 100 ml, respectively. Fish (common carp, silver carp and Nile tilapia) grown in these ponds were sampled at harvest and in local retail markets. Bacteriological examination of the fish sampled at harvest from both types of pond showed that they were of very good quality (2 - 3 pThC g(-1) fresh muscle weight), despite the skin and gut contents being very contaminated (10(2) - 10(3) pThC g(-1) fresh weight and 10(4) - 10(6) pThC g(-1) fresh weight, respectively). These results indicate that the WHO guideline quality of pThC g(-1) of chopped fresh fish (mainly flesh and skin contaminated with gut contents); this was due to the practice of the local fishmongers in descaling and chopping up the fish from both types of pond with the same knife and on the same chopping block. Fishmonger education is required to improve their hygienic practices; this should be followed by regular hygiene inspections.

  2. Health Status and the Demand for Healthcare among the Elderly in the Rural Quoc-Oai District of Hanoi in Vietnam

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    Kyung-Sook Bang

    2017-01-01

    Full Text Available Background. Vietnam is experiencing an unprecedented demographic transition. Its proportion of elderly people is growing rapidly. Objective. This study explored the health status and health-related quality of life (HRQoL of rural elderly Vietnamese and assessed their needs for healthcare services. Design. This study used a survey with stratified proportion sampling and quota assignment. In 2016, data was collected from 713 people in the rural Quoc-Oai district of Hanoi aged 60 or older. Results. The mean age of the respondents was 70.9. Both self-rated health status and functional status decreased with age. Women reported more functional limitations than men. Musculoskeletal disorders were the most frequently reported chronic diseases, followed by hypertension, gastrointestinal diseases, and cardiovascular diseases. Age, self-rated health status, BMIs, and the number of noncommunicable diseases (NCDs were found to be significant determinants of HRQoL, after controlling for socioeconomic effects. More than half the respondents requested more healthcare information, particularly on disease management. Conclusions. Vietnam’s healthcare system is being challenged to make health services easily accessible and meet the growing needs for chronic illness management, risk reduction, promoting healthy lifestyles, and improving the aging population’s quality of life.

  3. Necrosis avascular de ambas caderas y rodillas en una paciente con colitis ulcerosa tratada prolongadamente con corticoides a dosis altas A vascular necrosis of both hips and knees in a patient with ulcerative colitis treated for a long term with high-dose corticosteroids

    OpenAIRE

    A. Vidal Casariego; C. de la Cuerda Compés; I. Bretón Lesmes; M. Camblor Álvarez; C. Velasco Gimeno; P. García Peris

    2006-01-01

    INTRODUCCIÓN: La necrosis avascular representa la muerte del tejido óseo por fallo de su vascularización, y se asocia principalmente al uso de corticoides a dosis elevadas durante tiempo prolongado. CASO CLÍNICO: Una paciente de 25 años tratada con glucocorticoides a altas dosis durante 7 meses por colitis ulcerosa presenta dolor en ambas rodillas y movilidad limitada de caderas y rodillas. En la radiografía simple y la resonancia nuclear magnética (RNM) se observó necrosis avascular en dicha...

  4. Protocol for hospital based-surveillance of cerebral palsy (CP) in Hanoi using the Paediatric Active Enhanced Disease Surveillance mechanism (PAEDS-Vietnam): a study towards developing hospital-based disease surveillance in Vietnam.

    Science.gov (United States)

    Khandaker, Gulam; Van Bang, Nguyen; Dũng, Trịnh Quang; Giang, Nguyen Thi Huong; Chau, Cao Minh; Van Anh, Nguyen Thi; Van Thuong, Nguyen; Badawi, Nadia; Elliott, Elizabeth J

    2017-11-09

    The epidemiology, pathogenesis, management and outcomes of cerebral palsy (CP) in low-income and middle-income countries including Vietnam are unknown because of the lack of mechanisms for standardised collection of data. In this paper, we outline the protocol for developing a hospital-based surveillance system modelled on the Paediatric Active Enhanced Disease Surveillance (PAEDS) system in Australia. Using PAEDS-Vietnam we will define the aetiology, motor function and its severity, associated impairments, and nutritional and rehabilitation status of children with CP in Hanoi, Vietnam. These essential baseline data will inform future health service planning, health professional education and training, and family support. This is a hospital-based prospective surveillance of children with CP presenting to the rehabilitation, neurology and general paediatric services at the National Children's Hospital and St Paul Hospital in Hanoi. We will use active, prospective daily case-finding for all children with CP aged CP, known risk factors for CP, and nutrition, immunisation, education and rehabilitation status. This study was approved by the Hanoi Medical University Institutional Review Board (decision no 1722) and The University of Sydney Human Research Ethics Committee (approval no 2016/456). Establishment of PAEDS-Vietnam will enable hospital-based surveillance of CP for the first time in Vietnam. It will identify preventable causes of CP, patient needs and service gaps, and facilitate early diagnosis and intervention. Study findings will be disseminated through local and international conferences and peer-reviewed publications. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  5. Assessment of Tangible Direct Flood Damage Using a Spatial Analysis Approach under the Effects of Climate Change: Case Study in an Urban Watershed in Hanoi, Vietnam

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    Mohamed Kefi

    2018-01-01

    Full Text Available Due to climate change, the frequency and intensity of Hydro-Meteorological disasters, such as floods, are increasing. Therefore, the main purpose of this work is to assess tangible future flood damage in the urban watershed of the To Lich River in Hanoi, Vietnam. An approach based on spatial analysis, which requires the integration of several types of data related to flood characteristics that include depth, in particular, land-use classes, property values, and damage rates, is applied for the analysis. To simulate the future scenarios of flooding, the effects of climate change and land-use changes are estimated for 2030. Additionally, two scenarios based on the implementation of flood control measures are analyzed to demonstrate the effect of adaptation strategies. The findings show that climate change combined with the expansion of built-up areas increases the vulnerability of urban areas to flooding and economic damage. The results also reveal that the impacts of climate change will increase the total damage from floods by 26%. However, appropriate flood mitigation will be helpful in reducing the impacts of losses from floods by approximately 8% with the restoration of lakes and by approximately 29% with the implementation of water-sensitive urban design (WSUD. This study will be useful in helping to identify and map flood-prone areas at local and regional scales, which can lead to the detection and prioritization of exposed areas for appropriate countermeasures in a timely manner. In addition, the quantification of flood damage can be an important indicator to enhance the awareness of local decision-makers on improving the efficiency of regional flood risk reduction strategies.

  6. Assessment of inorganic content of PM{sub 2.5} particles sampled in a rural area north-east of Hanoi, Vietnam

    Energy Technology Data Exchange (ETDEWEB)

    Gatari, Michael J.; Boman, Johan; Wagner, Annemarie; Janhaell, Sara; Isakson, Jan [Chemistry Department, Atmospheric Science, Goeteborg University, SE-412 96 Goeteborg (Sweden)

    2006-09-15

    Atmospheric aerosols from seven rural sites in northern Vietnam, east of Hanoi, were sampled and analyzed. The aim of the study was to evaluate trace elemental and black carbon (BC) concentrations in fine particles (PM{sub 2.5}) and to investigate the influence of the Pha Lai power plant and other pollution sources on regional air quality. Seven measurement stations were set up at selected rural sites and a campaign consisting of 12 two-day measurement periods was conducted from the end of May until the end of October 2000. At each location a pair of samplers was installed consisting of a cyclone loaded with Teflon filters and a modified Millipore air monitoring cartridge loaded with glass fibre filters. The obtained samples were analyzed for trace elements by Energy Dispersive X-ray Fluorescence (EDXRF), while a black smoke detector was used for BC analysis. Seventeen trace elements were analyzed; Br, Ca, Cl, Cr, Cu, Fe, K, Mn, Ni, Pb, Rb, S, Se, Sr, Ti, V and Zn and their concentrations evaluated. The results showed that BC, Ca, Cl, Fe, K and S dominated in the sampled atmospheric aerosols. The measured concentrations of the potentially hazardous trace elements Cr, Mn, Ni and Pb were all below the limits defined by Vietnamese standards of ambient air quality. Statistical evaluations indicated that coal and heavy fuel oil combustion were major sources of atmospheric pollutants in the area and that biomass burning and road transport had a marked influence on regional air quality. It was concluded that the Pha Lai power plant was the major source of coal combustion emissions. Trace element emissions originating from river transportation were suggested as another major source of atmospheric pollutants. The results indicate that the elemental concentrations in PM{sub 2.5} are strongly influenced by seasonal variations. Further measurements are required to identify the impact of long-range transported continental air masses on the air quality of the investigated rural

  7. Efeito protetor do nifurtimox contra a reativação parasitária em pacientes cronicamente infectados pelo Trypanosoma cruzi e tratados com corticóide em virtude de afecções associadas Nifurtimox as a prophylatic drug to prevent reactivation in chronic chagasic patients treated with corticoid for associated diseases

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    Anis Rassi

    1998-06-01

    Full Text Available Pacientes na fase crônica da doença de Chagas foram tratados com corticóide em virtude de afecções associadas e, a fim de tentar coibir reativação da infecção pelo Trypanosoma cruzi, houve uso concomitante do nifurtimox. Levando em conta o verificado em pesquisa anterior, quando corticóide de fato promoveu aumento da parasitemia detectada pelo xenodiagnóstico, pôde ser notado que o nifurtimox mostrou-se apto a evitar a citada acentuação parasitária, podendo tal constatação ser útil em procedimentos assistenciais, quando circunstancialmente estiverem presentes doença de Chagas e imunodepressão.Patients in the chronic phase of Chagas' disease and receiving corticoid because of concommitant diseases were treated with nifurtimox. We proved in another paper that in the chronic phase of Chagas' disease corticoid use is associated with increased parasitemia, as evaluated by xenodiagnosis. In this study nifurtimox use prevented this increase, and we suggest that in immunocompromised patients with chronic Chagas' disease the use of this drug could be useful.

  8. Detection of pepper mild mottle virus as an indicator for drinking water quality in Hanoi, Vietnam, in large volume of water after household treatment.

    Science.gov (United States)

    Sangsanont, Jatuwat; The Dan, Dang; Thi Viet Nga, Tran; Katayama, Hiroyuki; Furumai, Hiroaki

    2016-11-09

    The aims of this study were to examine the removal of bacteria and viruses by household point-of-use (POU) treatments and to apply a previously developed large-volume virus concentration method (∼20 L). First, the removal of microbes by household POU treatment was investigated in the laboratory. Second, the prevalence of viruses in drinking water sources for households and the removal efficiency of microbes by POU treatments in two suburban communities in Hanoi, Vietnam, were investigated. Indigenous pepper mild mottle virus (PMMoV) was used as the main target together with adenovirus, Aichi virus, enterovirus, F-specific bacteriophage genogroup 1, and Escherichia coli to investigate the removal efficiency of household treatments. The results from laboratory and field survey were compared. From the laboratory study, ceramic membranes were not effective for removing viruses and bacteria from water; pathogen reduction was less than 1.5 log10. By contrast, reverse osmosis (RO) devices reduced microbes by 3 to > 5 log10. In a field study, PMMoV was found to be the most prevalent waterborne virus. Household sand filtration was ineffective for removing E. coli, total coliforms and PMMoV; the reduction was less than 1 order of magnitude. Boiling the water and then filtering it with a ceramic membrane reduced E. coli by 3 orders of magnitude, but this was not effective for removing PMMoV. RO filtration was one of the promising methods for removing E. coli, total coliforms and PMMoV to below their detection limits in most of the samples studied. The removal of E. coli, total coliforms and PMMoV was >2.3, >4 and >3 log10, respectively. The laboratory results of virus removal efficiency by POU devices agreed with the field study. Due to the prevalence and characteristics of PMMoV, it is a strong candidate for an indigenous indicator to investigate the viral removal efficiency of household POU treatments.

  9. Experimental investigation and modelling approach of the impact of urban wastewater on a tropical river; a case study of the Nhue River, Hanoi, Viet Nam

    Science.gov (United States)

    Duc, Trinh Anh; Vachaud, Georges; Bonnet, Marie Paule; Prieur, Nicolas; Loi, Vu Duc; Anh, Le Lan

    2007-02-01

    SummaryAnalyses of water quality and flow regime in combination with laboratory studies and ecological modelling were used to assess the water quality impact of pollution from to To Lich River that drains through Hanoi City and greatly contaminates the Nhue River. With an average discharge of 26.2 m 3/s, the Nhue River receives about 5.8 m 3/s of untreated domestic water from the city's main open-air-sewer - the To Lich River. The studies during 2002-2003 showed high concentrations of BOD (70 mg O 2/l), DOC (15 mg C/l), coliform (2.4e 6 MNP/100 ml), total phosphorus (3.5 mg P/l), and total nitrogen (31.6 mg N/l) in the To Lich, while DO level was less than 1 mg O 2/l. Such high loads of untreated wastewater impacted water quality in the Nhue River where DO decreased at times to as low as 1 mg O 2/l. The accumulation of particulate organic matter and micro-organisms in the sediments of the Nhue represented substantial sources of nutrients and sinks for DO. They are also considerable production of dissolved carbon dioxide at concentrations up to two orders of magnitude higher than pressure. Such pressures ( EpCO 2) are expected in polluted environments, but the results presented here are new for Vietnam and much of developing countries. A number of factors linked to field monitoring and laboratory measurements clearly indicate the importance of autotrophic over heterotrophic biological processes and sediments. An ecological model for management purposes has been developed that reliably estimates of the pollutant loads. An opportunity was taken to examine the changing impacts and processes when the To Lich was diverted from the Nhue. The monitoring and modelling of this opportunity showed low dissolved oxygen levels even if the impact from the To Lich was lessened. Alternatives are proposed to alleviate problems of water quality in the Nhue. It is concluded that the treatment of the To Lich River's water is highly recommended; otherwise a reduction to one third of

  10. AUTOMATED CLASSIFICATION OF LAND COVER USING LANDSAT 8 OLI SURFACE REFLECTANCE PRODUCT AND SPECTRAL PATTERN ANALYSIS CONCEPT - CASE STUDY IN HANOI, VIETNAM

    Directory of Open Access Journals (Sweden)

    D. Nguyen Dinh

    2016-06-01

    , develop land, barren and others. This paper provides a preliminary research result on application of multispectral image decomposition using simplified spectral pattern for classification of land cover for Hanoi area.

  11. Corticoide sistêmico como tratamento de primeira linha da hipertensão pulmonar secundária a síndrome POEMS Systemic corticosteroids as first-line treatment in pulmonary hypertension associated with POEMS syndrome

    Directory of Open Access Journals (Sweden)

    Samia Rached

    2009-08-01

    Full Text Available A síndrome POEMS é uma rara doença de plasmócitos. A ocorrência de hipertensão pulmonar como complicação respiratória da síndrome é pouco frequente e pode estar ligada ao aumento de várias citocinas, quimiocinas e fatores de crescimento como parte dos fenômenos inflamatórios que cercam a fisiopatologia da síndrome POEMS. Descrevemos o caso de uma mulher de 54 anos com síndrome POEMS e hipertensão pulmonar, que foi tratada com corticoide como terapia de primeira linha. Tratava-se de uma paciente com clássicos sintomas dessa síndrome: polineuropatia (confirmada por eletroneuromiografia, organomegalia, hipotireoidismo subclínico, gamopatia monoclonal em dosagem urinária e alterações cutâneas. A cateterização cardíaca direita revelou pressão arterial pulmonar média de 48 mmHg, débito cardíaco de 4,1 L/min e resistência vascular pulmonar de 8,05 Woods. O nível sérico de brain natriuretic peptide (BNP foi de 150 pg/mL. Nenhuma outra doença foi encontrada durante investigação. Prednisona (1 mg/kg por três meses foi iniciada, com dramática melhora clínica e funcional, além de normalização dos níveis dos hormônios tireoidianos e de proteína em urina por eletroforese. A pressão arterial pulmonar média caiu para 26 mmHg, o débito cardíaco para 3,8 L/min e a resistência vascular pulmonar para 2,89 Woods. O nível sérico de BNP caiu para 8pg/mL. Nossos achados indicam o potencial papel da corticoterapia como primeira linha de tratamento na hipertensão pulmonar associada à síndrome POEMS. Diante da raridade dessa apresentação, um registro multicêntrico deveria ser desenvolvido para permitir a aquisição de mais dados que suportem essa conduta.The POEMS syndrome is a rare plasma cell disease. Pulmonary hypertension is an infrequent respiratory complication of this syndrome and might be associated with increased levels of various cytokines, chemokines and growth factors as part of the inflammatory

  12. Opportunities for farmers: 'Safe' vegetables for Hanoi

    NARCIS (Netherlands)

    Wijk, van M.S.; Huu Cuong, T.; Nguyen Anh Tru,; Pham Van Hoi,

    2005-01-01

    Vietnamese boeren gebruiken voor de intensieve groententeelt veel verschillende pesticiden, waaronder zeer gevaarlijke. Nieuwe, winstgevende markten zijn een stimulans om over te gaan op meer duurzame productie. Het huidige marketing systeem maakt het moeilijk een 100 procent waterdichte "veilige"

  13. Hanoi and the American War: Two International Histories

    Directory of Open Access Journals (Sweden)

    Geoffrey C. Stewart

    2014-03-01

    Full Text Available Pierre Asselin, Hanoi’s Road to the Vietnam War, 1954-1965. Berkeley: University of California Press, 2013. 319 pp. $55 (cloth Lien-Hang T. Nguyen, Hanoi’s War: An International History of the War for Peace in Vietnam. Chapel Hill: The University of North Carolina Press, 2012. 444 pp. $34.95 (cloth.

  14. Constrained consumer practices and food safety concerns in Hanoi

    NARCIS (Netherlands)

    Wertheim-Heck, S.C.O.; Vellema, S.; Spaargaren, G.

    2014-01-01

    Food safety is a widely recognized concern in Vietnam. Public officials, companies and consumers find different ways to address risks of pesticide residues and bacterial contamination related to the use of fresh vegetables in daily diets. The response of the government to these food safety risks

  15. [Treatment of chronic Chagas' disease with an association of nifurtimox and corticoid].

    Science.gov (United States)

    Rassi, Anis; Amato Neto, Vicente; de Siqueira, Astolpho Ferraz; Ferriolli Filho, Francisco; Amato, Valdir Sabbaga; Rassi, Gustavo Gabriel; Rassi Junior, Anis

    2002-01-01

    Ten patients with chronic Chagas' disease were treated with nifurtimox (8-9 mg/kg/day) associated with betamethasone (9 mg/day initially and then gradually reduced) during 60 days, with one exception. It was intended to combine the respective anti-parasitic and anti-inflammatory actions of these drugs. The expected stimulating effect of betamethasone on the infection could possibly enhance the anti-Trypanosoma cruzi action of nifurtimox. Long term persistence of negative xenodiagnosis, used to control the results, was observed in only one of the cases. Regaridng the other patients, post-treatment positivity of xenodiagnosis and serological testes attested the failure of this therapy. As this study has demonstrated, adequate and long term follow-up of treated cases is necessary to ensure correct conclusions.

  16. Avaliação do uso de corticoide no tratamento da dengue

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    Avelino José da Silva Freitas Júnior

    2016-09-01

    Full Text Available A Dengue é uma doença febril causada por quatro sorotipos de um vírus do gênero Flavivirus. Ocorre em praticamente todas as regiões tropicais e subtropicais do planeta, atingindo cerca de 100 milhões de casos todos os anos. Sua apresentação clínica se divide em dengue clássica e dengue hemorrágica, sendo esta uma importante causa de óbitos. O uso de corticóide em seu tratamento é freqüentemente estudado, tendo em vista seu efeito antiinflamatório e imunossupressor, o que agiria exatamente na fisiopatogenia da doença. O presente estudo revisou a literatura acerca dos reais benefícios em incluir essa droga no manejo da fase aguda da dengue. Ao término, concluiu-se a partir da literatura, que não houve melhora significativa quando do uso de corticóides, e que seu uso não deve ser rotineiro.

  17. Efecto broncodilatador de fenoterol y salbutamol asociados a un corticoide en niños con crisis de asma.

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    Raúl Huaman

    1996-01-01

    Full Text Available RESUMEN Objetivo: Evaluar los efectos clínicos y colaterales de Fenoterol 100 ug/inh en microdosificador inhalatorio (MDI con aerocámara y salbutamol 100 ug/inh en MDI con aerocámara ambos asociados a dexametasona endovenosa (0.3 mg/kg en bolo. Material y métodos: En un estudio prospectivo, randomizado, multicéntrico se incluyó 60 niños con crisis asmática leve-moderada (30 para cada grupo. Ambos grupos fueron comparables en la evaluación inicial. Resultados: Fenoterol - Dexametasona dio mayor reducción del puntaje clínico (p<0.05 que Salbutamol - Dexametasona al minuto 120 (-2.86 vs -1.25 respectivamente. Asimismo un mayor aumento del Pico Espiratorio Forzado (PEF (p<0.05 al minuto 60 en comparación a Salbutamol - Dexametasona (135 vs 54 respectivamente. Tanto para frecuencia respiratoria como para presencia de tremor los 2 grupos fueron comparables en todos los momentos de la evaluación. No se encontró diferencia significativa entre ambos grupos en la cantidad de altas al final del estudio (4 horas. Conclusiones: Concluímos que las combinaciones Fenoterol - Dexametasona y Salbutamol - Dexametasona son igualmente efectivas en el manejo de crisis asmática leves a moderadas en niños. (Rev Med Hered 1996; 7: 4-10.

  18. An in vitro reproduction of stress-induced memory defects: Effects of corticoids on dendritic spine dynamics

    OpenAIRE

    Shinichi Saito; Satoshi Kimura; Naoki Adachi; Tadahiro Numakawa; Akihiko Ogura; Keiko Tominaga-Yoshino

    2016-01-01

    Previously, in organotypic slice culture of rodent hippocampus we found that three repeated inductions of LTP, but not a single induction, led to a slow-developing long-lasting enhancement of synaptic strength coupled with synapse formation. Naming this structural plasticity RISE (repetitive LTP-induced synaptic enhancement) and assuming it to be a potential in vitro reproduction of repetition-dependent memory consolidation, we are analyzing its cellular mechanisms. Here, we applied a glucoco...

  19. To Hanoi and Back: The United States Air Force and North Vietnam, 1966-1973

    Science.gov (United States)

    2000-01-01

    Surprise (London, 1995), and John Prados , “The Warning that Left Something to Chance: Intelligence at Tet,” Journal of American- East Asian Relations, summer...1993, pp 161–84. A revised version of the Prados article appears together with Mark Jacobsen’s “President Johnson and the Decision to Curtail Rolling...Anthis, Rollen H. “Airpower: The Paradox in Vietnam.” Air Force Magazine, April 1967, pp 34–38. Ariel (pseudonym of Morris J. Blachman). “The Stupidity

  20. Identifying and understanding consumers of wild animal products in Hanoi, Vietnam: implications for conservation management

    OpenAIRE

    Drury, R. C.

    2009-01-01

    Vietnam is an established thoroughfare for illegal wildlife trade, and rapidly growing urban prosperity is increasing domestic demand for wild animal products. Consumer-targeted interventions, including awareness campaigns and social marketing, and supply-side approaches such as wildlife farming to reduce demand for wild animals, are increasingly being used alongside regulatory measures to curb illegal trade. These approaches are based on limited information about wild animal consumers and co...

  1. The Micrograph Image of Early Experimental Dental Caries in Permanent Teeth in Hanoi Medical University

    Directory of Open Access Journals (Sweden)

    Truong Manh Dung

    2016-04-01

    Full Text Available Objectives: This reseach aimed to describe micrograph images of experimental carious lesions at early stage. Method:  Experimental study. 60 permanent extracted premolars (patient aged 18-25 were cleaned and removed remaining soft tissue. Each tooth  was painted with acid-resistant coating leaving an enamel window of approximately 1 × 1 mm2 in buccal surface. After 96 hours being soaked in demineralization solution to create artificial carious lesion, the coating  was removed, and all teeth  would be evaluated using ICDAS criteria and made tooth specimens to be observed under a scanning electronic microscope  (SEM. Results: After being soaked in demineralization solution, the carious lesion gained was at stage  ICDAS 1 with 66.7% ; and 33.3% at stage 2. Mean depth and area of the lesions was 107.6 µm and 1.14 µm2, respectively. The difference in depth and area of lesions between  group ICDAS 1 và ICDAS 2 was significantly statistical with p=0.0001. Micrograph images showed that after being soaked in demineralization solution, enamel surface became rough, enamel rods lost minerals in the body more than in the sheath, cross-sectional images showed widened gaps between the rods due to demineralization. There was a difference in demineralization degree between  group ICDAS 1 and 2. Conclusion: Image of cariouslesions gained after being soaked in demineralization solution showed that naturally carious and artificially carious-like lesions shared many similar characteristics due to theevaluation based on ICDAS criteria for detecting early  carious lesions and scanning electronic microscope. DOI: 10.14693/jdi.v23i1.973

  2. Health risk assessment along wastewater recovery and reuse systems in Kampala, Uganda and Hanoi, Vietnam

    OpenAIRE

    Fuhrimann, Samuel

    2015-01-01

    Background: Reuse and recovery of wastewater in agriculture and aquaculture has gained traction in the new millennium. In view of continued population growth, increasing scarcity of freshwater and other natural resources, the demand to boost food production and efforts to enhance wastewater reuse will increase in the years to come. Indeed, wastewater reuse and the recovery of water, nutrients and energy can generate promising business opportunities and support livelihoods in poor communities,...

  3. Habitat et environnement urbain au Viet-Nam: Hanoi et Hô Chi Minh ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    The editor. René Parenteau is a professor of urban planning at the Université de Montréal specializing in urban settlements (housing and environment). René has focused on the conditions prevailing in West Africa and South-East Asia's urban squatter areas since 1980. He has been working in Viet Nam since 1989.

  4. Torre de Hanoi: datos normativos y desarrollo evolutivo de la planificación

    Directory of Open Access Journals (Sweden)

    Alicia Díaz

    2012-06-01

    Full Text Available El objetivo de este trabajo ha sido evaluar el desarrollo evolutivo de la planificación y obtener datos normativos de la prueba de planificación “Torre de Hanoi” en escolares de Educación Primaria (EP. Con este propósito se ha seleccionado una muestra de 1.032 alumnos/as escolarizados desde primero hasta sexto curso de EP en la Comunidad Autónoma de Canarias, con edades comprendidas entre los 6 años y 3 meses y los 12 años y 4 meses. Se analizó el número de diseños correctamente realizados por los escolares en los diferentes cursos. Los resultados encontrados ponen de manifiesto la existencia de tres momentos diferenciados en el desarrollo de la planificación, observándose un rendimiento inferior del alumnado de primer curso frente al resto de los cursos y un rendimiento más similar entre, por un lado, el alumnado de segundo, tercero y cuarto, y, por otro lado, entre el de quinto y sexto curso. Asimismo, se observa una mejora progresiva en la planificación -en función de la edad. Por último, se presenta el baremo para EP de la prueba “Torre de Hanoi”

  5. The effects of innovation on firm performance of supporting industries in Hanoi, Vietnam

    Directory of Open Access Journals (Sweden)

    Nham Tuan

    2016-04-01

    Full Text Available Purpose: Innovation, including product, process, marketing, and organizational innovation within a firm, is considered as one of essential component for surviving and growing. These innovation activities create value and competitive advantages for successful organizations; therefore, understanding the organization’s overall innovation is the first and foremost to understand the role of innovation on firm performance. The objective of this research is to explore two parts: the impacts of innovation on the different aspect of innovation performance, then their effects to firm performance (production, market, and financial performance. Design/methodology/approach: This study uses primary data from questionnaire survey. The questionnaire involves 4 parts including general information, innovation activities; innovative performance, and firm performance. This research focuses on firms in supporting industries of mechanics, electronics, motorbike and automobile. These firms are in a list of companies (known as The Excellent Vietnamese Companies in Northern and Central Vietnam established by JETRO and VCCI. There are 150 firms in this list. The questionnaire survey was administered to directors, CEO of those firms during April and May, 2014. Out of the 150 questionnaires sent out, 118 were valid, accounting for 78.7% of the true response rate. Analysis methodologies of reliability, factor analysis and regression are utilized in this paper. Findings: The result demonstrated there are positive effects of process, marketing, and organizational innovations on firm performance in supporting firms. More specifically, the higher the level of innovation activities is, the greater the innovative performance is, which means the larger level of Process, organization and marketing innovation activities are, the higher level of innovative performance are likely to be. Secondly, the higher level of Process, organization and marketing innovative performance, the better level of firm performances is likely to be. To sum up, in order to improve the innovative and firm performance, those firms in supporting industry should highly concentrate on process, marketing, and organizational innovation activities, rather than product innovation activities. Originality/value: Initially, this study applies successfully the model which supposing innovation is a process, then clarifying innovation definition through the impact of innovation activities on innovative performances. Secondly, this research confirmed the positive impact of innovative performances on firm performances. It provided one more empirical evidence of the relationship between innovation and firm performance. For practitioners, organizational innovation and process innovation are more important factors affecting innovative performance and firm performance than product and marketing innovation. Therefore, enterprises should focus and mobilize resources to create improvement in organizational structure and manufacturing processes.

  6. The effects of innovation on firm performance of supporting industries in Hanoi, Vietnam

    Energy Technology Data Exchange (ETDEWEB)

    Tuan, N.; Nhan, N.; Giang, P.; Ngoc, N.

    2016-07-01

    Innovation, including product, process, marketing, and organizational innovation within a firm, is considered as one of essential component for surviving and growing. These innovation activities create value and competitive advantages for successful organizations; therefore, understanding the organization’s overall innovation is the first and foremost to understand the role of innovation on firm performance. The objective of this research is to explore two parts: the impacts of innovation on the different aspect of innovation performance, then their effects to firm performance (production, market, and financial performance). This study uses primary data from questionnaire survey. The questionnaire involves 4 parts including general information, innovation activities; innovative performance, and firm performance. This research focuses on firms in supporting industries of mechanics, electronics, motorbike and automobile. These firms are in a list of companies (known as The Excellent Vietnamese Companies in Northern and Central Vietnam) established by JETRO and VCCI. There are 150 firms in this list. The questionnaire survey was administered to directors, CEO of those firms during April and May, 2014. Out of the 150 questionnaires sent out, 118 were valid, accounting for 78.7% of the true response rate. Analysis methodologies of reliability, factor analysis and regression are utilized in this paper. The result demonstrated there are positive effects of process, marketing, and organizational innovations on firm performance in supporting firms. More specifically, the higher the level of innovation activities is, the greater the innovative performance is, which means the larger level of Process, organization and marketing innovation activities are, the higher level of innovative performance are likely to be. Secondly, the higher level of Process, organization and marketing innovative performance, the better level of firm performances is likely to be. To sum up, in order to improve the innovative and firm performance, those firms in supporting industry should highly concentrate on process, marketing, and organizational innovation activities, rather than product innovation activities. Initially, this study applies successfully the model which supposing innovation is a process, then clarifying innovation definition through the impact of innovation activities on innovative performances. Secondly, this research confirmed the positive impact of innovative performances on firm performances. It provided one more empirical evidence of the relationship between innovation and firm performance. For practitioners, organizational innovation and process innovation are more important factors affecting innovative performance and firm performance than product and marketing innovation. Therefore, enterprises should focus and mobilize resources to create improvement in organizational structure and manufacturing processes. (Author)

  7. Polimorfismos genéticos y respuesta a corticoides en pacientes de artritis reumatoide. Efecto sobre citocinas y células T reguladoras

    OpenAIRE

    Paz Cazón, Banesa de

    2016-01-01

    La artritis reumatoide (AR) es una enfermedad autoinmune sistémica caracterizada por una inflamación persistente de las articulaciones, que deriva en una destrucción progresiva, generando distintos grados de deformidad e incapacidad funcional. Caracterizada por un exceso de mediadores inflamatorios, están bien documentadas las alteraciones en los niveles de IL-10 y el TNFα, dos citocinas involucradas en la respuesta inflamatoria. Dado que la producción de estas moléculas está genéticamente ...

  8. Reproducibility of O-(2-{sup 18}F-fluoroethyl)-L-tyrosine uptake kinetics in brain tumors and influence of corticoid therapy: an experimental study in rat gliomas

    Energy Technology Data Exchange (ETDEWEB)

    Stegmayr, Carina; Schoeneck, Michael; Oliveira, Dennis; Willuweit, Antje [Institute of Neuroscience and Medicine, Research Center Juelich, Juelich (Germany); Filss, Christian; Coenen, Heinz H.; Langen, Karl-Josef [Institute of Neuroscience and Medicine, Research Center Juelich, Juelich (Germany); University of Aachen, Department of Nuclear Medicine and Neurology, Aachen (Germany); Galldiks, Norbert [Institute of Neuroscience and Medicine, Research Center Juelich, Juelich (Germany); University of Cologne, Department of Neurology, Cologne (Germany); Shah, N. Jon [Institute of Neuroscience and Medicine, Research Center Juelich, Juelich (Germany); University of Aachen, Department of Nuclear Medicine and Neurology, Aachen (Germany); Juelich-Aachen Research Alliance (JARA) - Section JARA-Brain, Juelich (Germany)

    2016-06-15

    Positron emission tomography (PET) using O-(2-{sup 18}F-fluoroethyl)-L-tyrosine ({sup 18}F-FET) is a well-established method for the diagnostics of brain tumors. This study investigates reproducibility of {sup 18}F-FET uptake kinetics in rat gliomas and the influence of the frequently used dexamethasone (Dex) therapy. F98 glioma or 9L gliosarcoma cells were implanted into the striatum of 31 Fischer rats. After 10-11 days of tumor growth, the animals underwent dynamic PET after injection of {sup 18}F-FET (baseline). Thereafter, animals were divided into a control group and a group receiving Dex injections, and all animals were reinvestigated 2 days later. Tumor-to-brain ratios (TBR) of {sup 18}F-FET uptake (18-61 min p.i.) and the slope of the time-activity-curves (TAC) (18-61 min p.i.) were evaluated using a Volume-of-Interest (VOI) analysis. Data were analyzed by two-way repeated measures ANOVA and reproducibility by the intraclass correlation coefficient (ICC). The slope of the tumor TACs showed high reproducibility with an ICC of 0.93. A systematic increase of the TBR in the repeated scans was noted (3.7 ± 2.8 %; p < 0.01), and appeared to be related to tumor growth as indicated by a significant correlation of TBR and tumor volume (r = 0.77; p < 0.0001). After correction for tumor growth TBR showed high longitudinal stability with an ICC of 0.84. Dex treatment induced a significant decrease of the TBR (-8.2 ± 6.1 %; p < 0.03), but did not influence the slope of the tumor TAC. TBR of {sup 18}F-FET uptake and tracer kinetics in brain tumors showed high longitudinal stability. Dex therapy may induce a minor decrease of the TBR; this needs further investigation. (orig.)

  9. No Associations Between Single Nucleotide Polymorphisms in Corticoid Receptor Genes and Heart Rate and Cortisol Responses to a Standardized Social Stress Test in Adolescents : The TRAILS Study

    NARCIS (Netherlands)

    Bouma, Esther M. C.; Riese, Harriette; Nolte, Ilja M.; Oosterom, Elvira; Verhulst, Frank C.; Ormel, Johan; Oldehinkel, Albertine J.

    Previously, sequence variation in the glucocorticoid (GR) and mineralocorticoid (MR) receptor genes (NR3C1 and NR3C2, respectively) have been found to be associated with physiological stress responses to social stress tests in small samples of adult men and oral contraceptives (OC) using women.

  10. Insights from the predicted interactions of plant derived compounds to the gluco-corticoid receptor as an alternative to dexa-methasone.

    Science.gov (United States)

    Sarmah, Rajeev

    2012-01-01

    Dexamethasone (DEX) an anti-inflamatory 9-fluoro-glucocorticoid, activates the cytosolic glucocorticoid receptor (GR) binding to its Ligand Binding Domain (LBD). The GR-ligand complex then translocates to the nucleus and binds to the Glucocorticoid Response Element (GRE) resulting up-regulation of target gene expression of anti-inflamatory proteins. DEX is one of the most effective ligand for GR activation but comply to side effects. Therefore, alternative for DEX - plant metabolites of Calotropis sp and Swertia chirata were screened using docking appraoch. These plants compounds were selected because; parts of these plants are widely used againsts inflamation, allergy, asthma etc. Three metabolites of Swertia chirata namely Gentianine (GENT), Xanthone (XANT) and Swerchirin (SWER) are found to be occupying the same binding pocket in the LBD of the GR (PDB ID 1M2Z). The binding affinity as reflected by binding energies of GENT-1M2Z, XANT-1M2Z and SWER-1M2Z are -5.6, -6.7 and -6.7, and all the output parameter of the respective compounds positively correlates with that of DEX-1M2Z with r = 0.9, 0.6 and 0.6 respectively indicating similar GR activation function. Visualization analysis of the models clearly indicates that GENT and SWER may be GR activators. Rest of the compounds mostly docked onto the surface of the receptor molecule.

  11. Función Suprarrenal en Pacientes con Síndrome Bronquial Obstructivo Tratados con Corticoides Sistémicos (Informe Preliminar)

    National Research Council Canada - National Science Library

    ARANCIBIA H, FRANCISCA; HOLMGREEN P, LINUS; MARTÍNEZ A, ALEJANDRO

    2009-01-01

    ...). Se ha recomendado un máximo de 5 días para evitar efectos adversos. No ha sido evaluado si tratamientos por cursos cortos pueden suprimir el eje adrenal. Objetivo: Evaluar la función del eje hipotálamo hipófisis suprarrenal (HHS...

  12. Drug loading optimization and extended drug delivery of corticoids from pHEMA based soft contact lenses hydrogels via chemical and microstructural modifications.

    Science.gov (United States)

    García-Millán, Eva; Koprivnik, Sandra; Otero-Espinar, Francisco Javier

    2015-06-20

    This paper proposes an approach to improve drug loading capacity and release properties of poly(2-hydroxyethyl methacrylate) (p(HEMA)) soft contact lenses based on the optimization of the hydrogel composition and microstructural modifications using water during the polymerization process. P(HEMA) based soft contact lenses were prepared by thermal or photopolymerization of 2-hydroxyethyl methacrylate (HEMA) solutions containing ethylene glycol di-methacrylate as crosslinker and different proportions of N-vinyl-2-pyrrolidone (NVP) or methacrylic acid (MA) as co-monomers. Transmittance, water uptake, swelling, microstructure, drug absorption isotherms and in vitro release were characterized using triamcinolone acetonide (TA) as model drug. Best drug loading ratios were obtained with lenses containing the highest amount (200 mM) of MA. Incorporation of 40% V/V of water during the polymerization increases the hydrogel porosity giving a better drug loading capacity. In vitro TA release kinetics shows that MA hydrogels released the drug significantly faster than NVP-hydrogels. Drug release was found to be diffusion controlled and kinetics was shown to be reproducible after consecutive drug loading/release processes. Results of p(HEMA) based soft contact lenses copolymerized with ethylene glycol dimethacrylate (EGDMA) and different co-monomers could be a good alternative to optimize the loading and ocular drug delivery of this corticosteroid drug. Copyright © 2015. Published by Elsevier B.V.

  13. Association between Formal Operational Thought and Executive Function as Measured by the Tower of Hanoi-Revised

    Science.gov (United States)

    Emick, J.; Welsh, M.

    2005-01-01

    Executive functions have been defined in the neuropsychological literature as those cognitive processes that underlie future-oriented, goal-directed behavior such as planning, working memory, inhibition, and self-monitoring. Piaget's final stage of cognitive development, formal operations, involves a systematic approach to problem solving that…

  14. Responses and structural recovery of periphytic diatom communities after short-term disturbance in some rivers (Hanoi, Vietnam)

    Energy Technology Data Exchange (ETDEWEB)

    Duong, T. T.; Feurtet-Mezel, A.; Coste, M.; Dang Dinh, K.

    2009-07-01

    Field transfer experiments of periphytic diatom assemblages developed on artificial substrates were set up to assess responses of periphytic diatom communities to environmental disturbances. Glass substrates were positioned for colonization in comparatively un polluted site (Red, in Red River) and heavily polluted site (TL. in Tolich River) at the beginning of the experiment. After a period of two weeks colonized glass substrates were transferred from Red site to TL site and to a moderate site (NT{sub 2} in Nhue River) and conversely, from TL site to Red site, and to NT{sub 2} site. Responses and capacity of periphytic diatom communities to adapt environmental changes were assessed by using cells density, diversity index, species richness, taxonomic composition and diatom indices after 2 and 4 weeks transfer periods and varied for each site. (Author)

  15. Two-year outcome of first-line antiretroviral therapy among HIV-1 vertically-infected children in Hanoi, Vietnam.

    Science.gov (United States)

    Pham, H V; Ishizaki, A; Nguyen, L V; Phan, C T T; Phung, T T B; Takemoto, K; Pham, A N; Bi, X; Khu, D T K; Ichimura, H

    2015-10-01

    A retrospective analysis of 86 HIV-1 vertically-infected Vietnamese children with a follow-up period >24 months after initiating antiretroviral therapy (ART) was performed from 2008 to 2012, to assess the outcome of first-line ART in resource-limited settings. Of the 86 children, 68 (79.1%) were treated successfully (plasma HIV-1 viral load [VL] failure groups was observed in VL, CD4(+) T-cell count or clinical stage at baseline; age at ART start; or ART regimen. All 14 children with VL >5000 copies/ml, one of four children with VL 1000-5000 copies/ml and none with VL failures among HIV-1 vertically-infected children in resource-limited settings. © The Author(s) 2015.

  16. Performance of Children with Developmental Dyslexia on Two Skill Learning Tasks--Serial Reaction Time and Tower of Hanoi Puzzle

    Science.gov (United States)

    Vakil, Eli; Lowe, Michal; Goldfus, Carol

    2015-01-01

    Among the various theories proposed to explain developmental dyslexia (DD), the theory of specific procedural learning difficulties has gained certain support and is the framework for the current research. This theory claims that an inability to achieve skill automaticity explains the difficulties experienced by individuals with DD. Previous…

  17. Study on treatment of domestic wastewater of an area in Tu Liem district, Hanoi, by water hyacinth

    OpenAIRE

    Pham, Khanh Huy; Nguyen, Pham Hong Lien

    2015-01-01

    Domestic wastewater is one of the most interested environmental issues in Vietnam, especially in big cities and suburban residential areas. Most of the wastewater was not treated in the right way before discharging to environment. In this research, the author used water hyacinth as a main aquatic plant in aquatic pond model to treat wastewater. The experiment was operated continuously in 1 year with hydraulic retention time (HRT) is 11 and 18 days. Hydraulic loading rate (HRL) is 300 and 500 ...

  18. Suicide attempts by poisoning in Hanoi, Vietnam: methods used, mental problems, and history of mental health care.

    Science.gov (United States)

    Tuan, Nguyen Van; Dalman, Christina; Thiem, Nguyen Viet; Nghi, Tran Viet; Allebeck, Peter

    2009-01-01

    The objective of this paper was to investigate methods of poisoning, presence of mental problems, and the rate of psychiatric care among suicide attempters in Vietnam. Three hundred and nine suicide attempters by poisoning admitted to Bach Mai Hospital's Poison Control Center were investigated by trained nurses and qualified psychiatrists. Standardized questionnaires were used to assess methods of suicide, presence of mental problems, and psychiatric care. The most common methods were poisoning by psychotropic drugs in urban, and pesticides in rural areas. ICD-10 confirmed disorders were present in 68% of the cases and 73% rated positive on SRQ-20. Most patients were not in contact with psychiatric care. Restrictions on availability and handling of drugs and pesticides should be reinforced. Better infrastructures are needed for identification and treatment of persons with mental disorders.

  19. Development of case studies in the Hue area to be used in the English language course at WRU Hanoi

    NARCIS (Netherlands)

    Van der Neut, E.M.; Van Zuylen, J.A.; Verduijn, M.; Nederhoff, C.M.; Van der Zwaag, J. .

    2013-01-01

    The Thua Thien-Hue province, and especially the area around the city of Hue, is characterized by a small distance between mountains in the west and a flat coast with a coastal barrier in the east. The largest river in the area, the Huong river, flows through the city of Hue and is used for fishery,

  20. Genetic analysis of 55 northern Vietnamese patients with Wilson ...

    Indian Academy of Sciences (India)

    2017-12-19

    Dec 19, 2017 ... Center for Gene-Protein Research, Hanoi Medical University, Hanoi 100000, Vietnam; Department of Biochemistry, Hanoi Medical University, Hanoi 100000, Vietnam; Clinical Genetics Unit, Department of Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, 17176 Stockholm, Sweden ...

  1. Doença de lesões mínimas e glomeruloesclerose segmentar e focal em adultos: resposta a corticoide e risco de insuficiência renal

    Directory of Open Access Journals (Sweden)

    Lúcio R. R. Moura

    2015-12-01

    Full Text Available Resumo Introdução: O perfil clínico de pacientes brasileiros adultos com síndrome nefrótica por doença de lesões mínimas (LM e glomeruloesclerose segmentar e focal (GESF é pouco conhecido. Objetivo: Avaliamos as características clínico-laboratoriais e resposta a tratamento em pacientes adultos com síndrome nefrótica e diagnósticos histológicos de LM ou GESF. Métodos: Fez-se a análise retrospectiva de 50 pacientes adultos com LM e 120 com GESF. Todos os pacientes foram inicialmente tratados com corticosteroide. Os desfechos do estudo foram: resposta a corticosteroide, prevalência de remissão total, progressão para doença renal crônica estágio 5 (DRC5 e necessidade de terapia de substituição renal por DRC5. Resultados: Níveis iniciais de creatinina sérica foram 24% mais elevados entre pacientes com GESF (p = 0,02 e os de proteinúria foram 36% mais altos em LM (p < 0,001. Pacientes com LM foram córtico-sensíveis em 80% dos casos, com remissão total em 74%, e os pacientes com GESF em 58% (p = 0,01, com remissão total em 30% (p = 0,002. A prevalência de insuficiência renal aguda em pacientes com GESF foi de 39% (vs. 12%, p = 0,013 e DRC5 de 10% (vs. 0%, p < 0,001. Remissão completa ou parcial com o uso de corticosteroide reduziu em 83% o risco de DRC5 (p < 0,001 e remissão total associou-se a redução no risco de DRC5 de 89% (p < 0,001. Conclusão: A resposta positiva à corticoterapia foi o fator mais importante relacionado à preservação da função renal ao longo de mais de uma década de seguimento, e GESF relacionou-se a menor índice de resposta a corticosteroide.

  2. Knowledge of HIV and factors associated with attitudes towards HIV among final-year medical students at Hanoi medical university in Vietnam

    National Research Council Canada - National Science Library

    Platten, Michael; Pham, Ha N; Nguyen, Huy V; Nguyen, Nhu T; Le, Giang M

    2014-01-01

    .... The objective of this paper is to assess the gaps in knowledge of HIV and factors associated with discriminatory attitudes towards persons living with HIV among medical students in order to improve medical training...

  3. The Prevalence and Correlates of HIV and Undiagnosed Infection among Men Who Have Sex with Men in Hanoi, Vietnam : Findings from a Cross-sectional, Biobehavioral Study

    NARCIS (Netherlands)

    Vu, Nga Thi Thu; Holt, Martin; Phan, Huong Thi Thu; La, Lan Thi; Tran, Gioi Minh; Doan, Tung Thanh; de Wit, John

    2016-01-01

    INTRODUCTION: Men who have sex with men (MSM) are a key population for HIV infection in Vietnam, and the use of amphetamine type substances (ATS) is prevalent and possibly increasing in this population. The reported analysis examines the association between ATS use before or during sex and HIV

  4. Re-Framing Resilient Urbanism. A Smart Alternative to Generic New Towns Development in South-East Asia : The Case of Hanoi (Vietnam)

    NARCIS (Netherlands)

    Calabrese, L.M.; Qu, L.; Van Faassen, W.

    2015-01-01

    Resilient Urbanism is a broad concept that seeks to explore a wide spectrum of topics related to what makes resilience in urban contexts unique: spatial challenges, social and economic equity, climate change, density, mobility, governance, and other characteristics related to the unpredictable and

  5. Influence of meteorological conditions on PM 2.5 and PM 2.5-10 concentrations during the monsoon season in Hanoi, Vietnam

    Science.gov (United States)

    Hien, P. D.; Bac, V. T.; Tham, H. C.; Nhan, D. D.; Vinh, L. D.

    Twenty-four hour samples of air particulate matter with aerodynamic diameters from 2 to 10 μm (PM 10) and garden where routine surface observations and upper air radiosoundings were conducted. Very high PM 2.5 and PM 2.5-10 concentrations were observed in conjunction with the occurrence of nocturnal radiation inversions from October to December and subsidence temperature inversions (STI) from January to March. In the first case, the PM 2.5-10 fraction was much enhanced and particulate pollution was significantly higher at night than in daytime. During the occurence of STIs particulate mass was almost evenly distributed among the two fractions and no significant diurnal variations in concentrations were observed. In summer (May-September) particulate pollution was much lower than in winter. The multiple regression of 24-h particulate concentrations against meteorological parameters for both the winter and summer monsoon periods shows that the most important determinants of PM 2.5 are wind speed and air temperature, while rainfall and relative humidity largely control the daily variations of PM 2.5-10, indicating the high abundance of soil dust in this fraction. As to turbulence parameters, among the determinants of 24-h particulate concentrations are the vertical gradients of potential temperature and wind speed recorded at 06.30 and 18.30, respectively. Meteorological parameters could explain from 60% to 74% of the day-to-day variations of particulate concentrations.

  6. Twenty year results on application of induced mutation in soybean (Glycine max (L.) Merr.) breeding at Agricultural Genetics Institute (AGI), Hanoi, Vietnam

    Energy Technology Data Exchange (ETDEWEB)

    Mai Quang Vinh; Phan Phai; Ngo Phuong Thinh; Tran Dinh Dong; Tran Thuy Oanh [Agricultural Genetics Institute (AGI), Hanoi (Viet Nam)

    2001-03-01

    Research on application of the induced mutation method combined with crossing in soybean breeding for 20 years (1980-2000) plays an important role in research work at AGI, (Ministry of Agriculture and Rural Development of Vietnam). 23 soybean varieties and hybrid lines (including 6 local cultivars, 14 selected and introduced varieties, 3 hybrid lines) were treated with Roentgen ray irradiation, Gamma Ray {sup 60}Co with doses 7, 10, 12, 15, 18, 20 krad, and with chemical mutagens: EI, NMU, DNMU, DES, EMS, DEU with various concentrations 0.008, 0.02, 0.04, 0.06, 0.08%. As the results, we obtained the important conclusions about the rule of induced mutation process in soybean in the natural conditions of Vietnam. 8 mutant varieties [1 National varieties (DT84) and 6 regional production varieties (DT83, DT90, DT94, DT95, DT99, AK06 (DT-55))]. Several promising varieties were selected and released for farmers to produce in the large areas that occupied 50-90% percentage of soybean cultivated areas in Vietnam. These varieties have high-yield 1.5-3.5 tons/ha, short growth duration 75-100 days, tolerance to cold and hot temperature and can be planted in 3 crops per year (Winter, Spring and Summer season) over 35-40 thousands ha/year. At present, the mutagens are being used for defect-orientated repair of some promising hybrid lines, in order to contribute new good varieties to soybean production in Vietnam. (author)

  7. Microarthropod community structures (Oribatei and Collembola) in ...

    Indian Academy of Sciences (India)

    Therefore they can be used as bioindicators of forest plant succession. In Tam ... 560 064, India; Permanent address: Centre for Biodiversity, C/o Agro-Biology Faculty, Hanoi National Pedagogic University, Dai Hoc Su Pham Hanoi, Cau Giay, Vietnam; Institute of Ecology and Biological Resources, Nghia Do, Hanoi, Vietnam ...

  8. Therapeutic usage of omeprazole and corticoid in a dog with hydrocephalus unresponsive to conventional therapyUso terapêutico da associação do omeprazol com corticóide em um cão com hidrocefalia não-responsiva ao tratamento convencional

    Directory of Open Access Journals (Sweden)

    Alexandre Mendes Amude

    2013-05-01

    Full Text Available Medical therapy for hydrocephalus includes the administration of medications to limit the production of the cerebrospinal fluid (CSF resulting in reduced intracranial pressure (ICP. This report describes the clinical findings in one dog with congenital hydrocephalus that was unresponsive to conventional medical treatment with steroids, but demonstrated good response to omeprazole when this drug was added to the steroid. Omeprazole might decrease the CSF production by about 26% according to experimental studies with healthy dogs, but the usage of the omeprazole in clinical trials with affected dogs such as hydrocephalic animals is lacking. The results of this report might suggest that omeprazole can be used added to steroids to ameliorate the neurological status in dogs with increased ICP by hydrocephalus.O tratamento médico para a hidrocefalia inclui a administração de medicamentos para limitar a produção do fluido cerebroespinhal (FCE, resultando em redução da pressão intracraniana (PIC. Este trabalho descreve os achados clínicos em um cão com hidrocefalia congênita não responsiva ao tratamento médico convencional com esteróides mas que apresentou boa resposta à associação omeprazolesteróides. O omeprazol pode diminuir a produção de FCE em cerca de 26% de acordo com estudos experimentais realizados com cães saudáveis. Porém, o uso do omeprazol em ensaios clínicos com cães enfermos, como os animais hidrocefálicos, não é descrito. Os resultados deste trabalho sugerem que o omeprazol pode ser empregado em associação ao corticóide para melhorar o estado neurológico em cães com aumento da PIC devido à hidrocefalia.

  9. Marketing channel choice and marketing timing of peri-urban vegetable growers in Vietnam

    NARCIS (Netherlands)

    Wiersinga, R.C.; Wijk, van M.S.; Luyen, C.H.; Hoi, P.V.

    2007-01-01

    Agriculture is an important sector in the peri-urban area of Hanoi. It supplies 62 to 80% of vegetable consumption, of which 28% comes from Dong Anh district, which borders Hanoi City. Growing vegetables is an important income source for the farmers in Dong Anh as it contributes about 30% to their

  10. Characteristics of the Vietnamese Rural Economy

    DEFF Research Database (Denmark)

    Tarp, Finn

    Research report prepared under Component 5 of the Business Sector Development Programme (BSPS), Hanoi, Vietnam and the Agricultural Sector Programme Support (ASPS), 2011......Research report prepared under Component 5 of the Business Sector Development Programme (BSPS), Hanoi, Vietnam and the Agricultural Sector Programme Support (ASPS), 2011...

  11. Total energy calculation of perovskite, BaTiO3, by self-consistent ...

    Indian Academy of Sciences (India)

    Author Affiliations. B T Cong1 P N A Huy1 P K Schelling2 J W Halley3. Faculty of Physics, Hanoi University of Science, 334 Nguyen Trai Street, Hanoi, Vietnam; Argonne National Laboratory, USA; School for Physics and Astronomy, University of Minnesota, USA ...

  12. National Unity and Ethnic Identity in a Vietnamese University

    Science.gov (United States)

    Tran, Linh T.; Walter, Pierre G.

    2010-01-01

    In this article, the authors discuss the ways in which Vietnam's educational policies for ethnic minorities are enacted in the bachelor of arts (BA) program in ethnic minority cultures (EMC) at the Hanoi University of Culture (HUC). Hanoi University of Culture is one of only two universities in Vietnam that offer this program. Although the BA is…

  13. Celulitis por Microascus trigonosporus(anamorfo Scopulariopsis trigonospora)

    National Research Council Canada - National Science Library

    DELIA CANLE CORTIÑAS; RICARDO FERNÁNDEZ RODRÍGUEZ; ANA CID LAMA; MARIA DOLORES DÍAZ LÓPEZ

    2013-01-01

    ... régimen de tratamiento para las infecciones por Scopulariopsis spp. Presentamos un caso excepcional de celulitis por Microascus trigonosporus en un paciente con tratamiento prolongado con corticoides. Abstract...

  14. Glucocorticoid Regulation of Rat Renal Sodium Potassium Adenosine Triphosphatase

    Science.gov (United States)

    1990-03-29

    response is not mediated by de novo protein synthesis but is secondary to enhanced sodium influx. The osmotic diuresis seen in uncontrolled... corticoids restored NaK-ATPase activity. Many other workers have provided data supporting these findings in the kidney (Hendler et al., 1972; Charney et al...and dexamethasone. Use of these compounds permitted quantitation of gluco- corticoid /cytoplasmic receptor binding (Beato & Feigelson, 1972

  15. Annual Research Progress Report, Fiscal Year 1980

    Science.gov (United States)

    1980-10-01

    Number Page C-34-79 Triple Corticoid Integrated System (TCIS) 0.015% Cream 48 Compared to 0.5% Hydrocortisone Cream in Treating Lichen Planus. (0) C-35...Proj No: C-34-79 Status: Ongoing TITLE: Triple Corticoid Integrated System (TCIS) 0.015% Cream Compared to 0.5% Hydrocortisone Cream in Treating Lichen...of toxicity of this agent with the use of IV hydration only or IV hydration and mannitol diuresis . Technical Approach: Patients with histologically

  16. Traqueostomia percutânea: técnica ideal?

    OpenAIRE

    Rodrigo Afonso da Silva Sardenberg; Avertano,Antonio Bomfim M.; Younes,Riad N.

    2011-01-01

    A traqueostomia percutânea tem substituído a traqueostomia convencional em muitas Unidades de Terapia Intensiva, devido à facilidade e segurança do método realizado à beira do leito, dispensando o transporte do paciente da Unidade de Terapia Intensiva para o Centro Cirúrgico. Alguns autores sugerem que a dissecção limitada resulta em menor dano tecidual, diminui o risco de sangramento e infecção de ferida operatória. Esta revisão visa analisar e sintetizar estudos prospectivos e randomizados,...

  17. Tips for Beginners: Attention Getters.

    Science.gov (United States)

    Moldavan, Carla

    1993-01-01

    Proposes the use of humor and the personalization of word problems by inserting students' names in the problem statement as methods of gaining students' attention. Illustrates their use in a mixture problem and the Tower of Hanoi problem. (MDH)

  18. Interview de l'astrophysicien Trinh Xuan Thuan: du Big Bang à la naissance de la vie

    CERN Multimedia

    Lorens, Sachat

    2006-01-01

    Born in Hanoi, the astrophysicist is Professor of astronomy at Virginia University, and wrote many books of scientific popularization. His last book "Origines" makes the family treee of the world, from the Big Bang to the birth of alive beings

  19. Occurrence and species distribution of fishborne zoonotic trematodes in wastewater‐fed aquaculture in northern Vietnam

    National Research Council Canada - National Science Library

    Hop, Nguyen Thi; De, Nguyen Van; Murrell, Darwin; Dalsgaard, Anders

    2007-01-01

    ...‐urban areas of northern Vietnam. Methods  We collected 1200 fish from aquaculture systems receiving wastewater from the cities of Hanoi and Nam Dinh in northern Vietnam and examined them for zoonotic metacercariae...

  20. North Vietnam’s Military Logistics System: Its Contribution to the War, 1961-1969

    Science.gov (United States)

    1977-06-10

    air strikes* In effect Mullin, "Crops of Pineapple Gravel," pp. 14-15. 94J.. Military Assistance Comrmnds, Vie ta-ams "Monithl~y Evalv.a- tion Report...lyRevieVw Peel 1970 0 On. Aan. We Will Wine Hanoi: I oreign Languages Puiblishing Houses 1960e -. e ’is Wmr Feople g Army, Hanois Foreign Language. . gLele

  1. Sex differences in clinical characteristics, hospital management practices, and in-hospital outcomes in patients hospitalized in a Vietnamese hospital with a first acute myocardial infarction.

    Science.gov (United States)

    Nguyen, Hoa L; Ha, Duc Anh; Phan, Dat Tuan; Nguyen, Quang Ngoc; Nguyen, Viet Lan; Nguyen, Nguyen Hanh; Nguyen, Ha; Goldberg, Robert J

    2014-01-01

    Cardiovascular disease is one of the leading causes of morbidity and mortality in Vietnam. We conducted a pilot study of Hanoi residents hospitalized with acute myocardial infarction (AMI) at the Vietnam National Heart Institute in Hanoi. The objectives of this observational study were to examine sex differences in clinical characteristics, hospital management, in-hospital clinical complications, and mortality in patients hospitalized with an initial AMI. The study population consisted of 302 Hanoi residents hospitalized with a first AMI at the largest tertiary care medical center in Hanoi in 2010. The average age of study patients was 66 years and one third were women. Women were older (70 vs. 64 years) and were more likely than men to have had hyperlipidemia previously diagnosed (10% vs. 2%). During hospitalization, women were less likely to have undergone percutaneous coronary intervention (PCI) compared with men (57% vs. 74%), and women were more likely to have developed heart failure compared with men (19% vs. 10%). Women experienced higher in-hospital case-fatality rates (CFRs) than men (13% vs. 4%) and these differences were attenuated after adjustment for age and history of hyperlipidemia (OR: 2.64; 95% CI: 1.01, 6.89), and receipt of PCI during hospitalization (OR: 2.09; 95% CI: 0.77, 5.09). Our pilot data suggest that among patients hospitalized with a first AMI in Hanoi, women experienced higher in-hospital CFRs than men. Full-scale surveillance of all Hanoi residents hospitalized with AMI at all Hanoi medical centers is needed to confirm these findings. More targeted and timely educational and treatment approaches for women appear warranted.

  2. Sex differences in clinical characteristics, hospital management practices, and in-hospital outcomes in patients hospitalized in a Vietnamese hospital with a first acute myocardial infarction.

    Directory of Open Access Journals (Sweden)

    Hoa L Nguyen

    Full Text Available BACKGROUND: Cardiovascular disease is one of the leading causes of morbidity and mortality in Vietnam. We conducted a pilot study of Hanoi residents hospitalized with acute myocardial infarction (AMI at the Vietnam National Heart Institute in Hanoi. The objectives of this observational study were to examine sex differences in clinical characteristics, hospital management, in-hospital clinical complications, and mortality in patients hospitalized with an initial AMI. METHODS: The study population consisted of 302 Hanoi residents hospitalized with a first AMI at the largest tertiary care medical center in Hanoi in 2010. RESULTS: The average age of study patients was 66 years and one third were women. Women were older (70 vs. 64 years and were more likely than men to have had hyperlipidemia previously diagnosed (10% vs. 2%. During hospitalization, women were less likely to have undergone percutaneous coronary intervention (PCI compared with men (57% vs. 74%, and women were more likely to have developed heart failure compared with men (19% vs. 10%. Women experienced higher in-hospital case-fatality rates (CFRs than men (13% vs. 4% and these differences were attenuated after adjustment for age and history of hyperlipidemia (OR: 2.64; 95% CI: 1.01, 6.89, and receipt of PCI during hospitalization (OR: 2.09; 95% CI: 0.77, 5.09. CONCLUSIONS: Our pilot data suggest that among patients hospitalized with a first AMI in Hanoi, women experienced higher in-hospital CFRs than men. Full-scale surveillance of all Hanoi residents hospitalized with AMI at all Hanoi medical centers is needed to confirm these findings. More targeted and timely educational and treatment approaches for women appear warranted.

  3. Drug use and self-medication among children with respiratory illness or diarrhea in a rural district in Vietnam: a qualitative study

    Directory of Open Access Journals (Sweden)

    Le TH

    2011-09-01

    Full Text Available Thi Hoan Le1,2, Ellinor Ottosson3, Thi Kim Chuc Nguyen4, Bao Giang Kim5, Peter Allebeck11Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden; 2Department of Environmental Health, Hanoi Medical University, Hanoi, Vietnam; 3Department of Medicine, Gothenburg University, Gothenburg, Sweden; 4Department of Family Medicine, Hanoi Medical University, Hanoi, Vietnam; 5Department of Health Education, Hanoi Medical University, Hanoi, VietnamAims: To explore the knowledge, attitudes, and behaviors of parents in their use of drugs for respiratory illness or diarrhea among children under 5 years of age, and to understand factors influencing self-medication.Methods: A qualitative study was conducted, using in-depth interviews with two drug sellers and three health care providers, and four focus-group discussions with mothers of children under 5 years of age. Verbatim transcriptions were analyzed, and emerging themes and categories identified, using content analysis.Results: Use of a number of different drugs was reported, including broad-spectrum antibiotics and corticosteroids. There was poor awareness of side-effects, antibiotic resistance, and drug efficacy. Factors influencing self-medication were perceptions of the illness in the child, waiting time, and convenience, the attitudes of public health medical staff, insufficient drug supply in public health facilities, and poor control of prescribed drugs on the market.Conclusion: Misuse and misconceptions regarding drug use gave rise to considerable problems. Mothers' knowledge and attitudes to illness and health care services played an important role in determining the nature of self-medication. Financial barriers were not the only obstacle to adequate treatment. Health services should be more accessible and responsive to the needs of the population.Keywords: health services, parental attitudes, education

  4. Prevalence of comorbidities and their impact on hospital management and short-term outcomes in Vietnamese patients hospitalized with a first acute myocardial infarction.

    Directory of Open Access Journals (Sweden)

    Hoa L Nguyen

    Full Text Available Cardiovascular disease is one of the leading causes of morbidity and mortality in Vietnam. We conducted a pilot study of Hanoi residents hospitalized with a first acute myocardial infarction (AMI at the Vietnam National Heart Institute in Hanoi for purposes of describing the prevalence of cardiovascular (CVD and non-CVD comorbidities and their impact on hospital management, in-hospital clinical complications, and short-term mortality in these patients.The study population consisted of 302 Hanoi residents hospitalized with a first AMI at the largest tertiary care medical center in Hanoi in 2010.The average age of study patients was 66 years and one third were women. The proportions of patients with none, any 1, and ≥ 2 CVD comorbidities were 34%, 42%, and 24%, respectively. Among the CVD comorbidities, hypertension was the most commonly reported (59%. There were decreasing trends in the proportion of patients who were treated with effective cardiac medications and coronary interventions as the number of CVD comorbidities increased. Patients with multiple CVD comorbidities tended to develop acute clinical complications and die at higher rates during hospitalization compared with patients with no CVD comorbidities (Odds Ratio: 1.40; 95% Confidence Interval: 0.40-4.84.Our data suggest that patients with multiple cardiac comorbidities tended to experience high in-hospital death rates in the setting of AMI. Full-scale surveillance of Hanoi residents hospitalized with AMI at all Hanoi hospitals is needed to confirm these findings. Effective strategies to manage Vietnamese patients hospitalized with AMI who have multiple comorbidities are warranted to improve their short-term prognosis.

  5. Prevalence of comorbidities and their impact on hospital management and short-term outcomes in Vietnamese patients hospitalized with a first acute myocardial infarction.

    Science.gov (United States)

    Nguyen, Hoa L; Nguyen, Quang Ngoc; Ha, Duc Anh; Phan, Dat Tuan; Nguyen, Nguyen Hanh; Goldberg, Robert J

    2014-01-01

    Cardiovascular disease is one of the leading causes of morbidity and mortality in Vietnam. We conducted a pilot study of Hanoi residents hospitalized with a first acute myocardial infarction (AMI) at the Vietnam National Heart Institute in Hanoi for purposes of describing the prevalence of cardiovascular (CVD) and non-CVD comorbidities and their impact on hospital management, in-hospital clinical complications, and short-term mortality in these patients. The study population consisted of 302 Hanoi residents hospitalized with a first AMI at the largest tertiary care medical center in Hanoi in 2010. The average age of study patients was 66 years and one third were women. The proportions of patients with none, any 1, and ≥ 2 CVD comorbidities were 34%, 42%, and 24%, respectively. Among the CVD comorbidities, hypertension was the most commonly reported (59%). There were decreasing trends in the proportion of patients who were treated with effective cardiac medications and coronary interventions as the number of CVD comorbidities increased. Patients with multiple CVD comorbidities tended to develop acute clinical complications and die at higher rates during hospitalization compared with patients with no CVD comorbidities (Odds Ratio: 1.40; 95% Confidence Interval: 0.40-4.84). Our data suggest that patients with multiple cardiac comorbidities tended to experience high in-hospital death rates in the setting of AMI. Full-scale surveillance of Hanoi residents hospitalized with AMI at all Hanoi hospitals is needed to confirm these findings. Effective strategies to manage Vietnamese patients hospitalized with AMI who have multiple comorbidities are warranted to improve their short-term prognosis.

  6. Overnight improvements in two REM sleep-sensitive tasks are associated with both REM and NREM sleep changes, sleep spindle features, and awakenings for dream recall.

    Science.gov (United States)

    Nielsen, T; O'Reilly, C; Carr, M; Dumel, G; Godin, I; Solomonova, E; Lara-Carrasco, J; Blanchette-Carrière, C; Paquette, T

    2015-07-01

    Memory consolidation is associated with sleep physiology but the contribution of specific sleep stages remains controversial. To clarify the contribution of REM sleep, participants were administered two REM sleep-sensitive tasks to determine if associated changes occurred only in REM sleep. Twenty-two participants (7 men) were administered the Corsi Block Tapping and Tower of Hanoi tasks prior to and again after a night of sleep. Task improvers and non-improvers were compared for sleep structure, sleep spindles, and dream recall. Control participants (N = 15) completed the tasks twice during the day without intervening sleep. Overnight Corsi Block improvement was associated with more REM sleep whereas Tower of Hanoi improvement was associated with more N2 sleep. Corsi Block improvement correlated positively with %REM sleep and Tower of Hanoi improvement with %N2 sleep. Post-hoc analyses suggest Tower of Hanoi effects-but not Corsi Block effects-are due to trait differences. Sleep spindle density was associated with Tower of Hanoi improvement whereas spindle amplitude correlated with Corsi Block improvement. Number of REM awakenings for dream reporting (but not dream recall per se) was associated with Corsi Block, but not Tower of Hanoi, improvement but was confounded with REM sleep time. This non-replication of one of 2 REM-sensitive task effects challenges both 'dual-process' and 'sequential' or 'sleep organization' models of sleep-dependent learning and points rather to capacity limitations on REM sleep. Experimental awakenings for sampling dream mentation may not perturb sleep-dependent learning effects; they may even enhance them. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. 1936-37年ハノイにおける労働者ストライキ運動

    OpenAIRE

    岡田, 友和

    2015-01-01

    What began as a series of small labor strikes in Hanoi in the fall of 1936 had developed into a major movement by the beginning of 1937. According to police investigations, it was members of the small newspaper company Le Travail who incited Hanoi labor to strike. But why was the Le Travail group concerned in this movement? What was the Le Travail group? What was its purpose? We analyze this social movement in the worldwide context of the economic crisis after 1930 and the application of the ...

  8. Um modelo tridimensional para túneis escavados em rocha reforçada por tirantes passivos

    OpenAIRE

    Eduardo Costa Couto

    2011-01-01

    No presente trabalho, é apresentado um modelo numérico para análise tridimensional de túneis escavados em maciços rochosos reforçados por tirantes aderidos ao longo de todo o seu comprimento. O método numérico utilizado é o método dos elementos finitos. A abordagem usada na modelagem da interação maciço/tirante é o método de homogeneização de meios periódicos. Essa abordagem substitui o meio compósito constituído de rocha e tirantes por um meio homogeneizado equivalente, dispensando a tarefa ...

  9. DESFIBRAMENTO DE CAVACOS LAMINADOS DE BAMBUSA VULGARIS SCHRAD VISANDO À EXTRAÇÃO DE AMIDO

    Directory of Open Access Journals (Sweden)

    AZZINI ANISIO

    1998-01-01

    Full Text Available No presente estudo, cavacos laminados de Bambusa vulgaris Schrad com espessura reduzida (0,5 mm foram desfibrados visando à extração de amido e à separação das frações fibrosa e residual. O desfibramento dos cavacos foi realizado em liquidificador de copo invertido. Os resultados variaram de 52,16 a 69,36 g/kg para o amido, de 774,53 a 798,26 g/kg para a fração fibrosa e de 72,50 a 112,44 g/kg para a fração residual. O emprego de cavacos laminados com espessura variando de 0,403 a 0,489 mm favoreceu o desfibramento: viabilizou a extração de amido, dispensando o pré-amolecimento dos cavacos.

  10. Traqueostomia percutânea: técnica ideal?

    Directory of Open Access Journals (Sweden)

    Rodrigo Afonso da Silva Sardenberg

    Full Text Available A traqueostomia percutânea tem substituído a traqueostomia convencional em muitas Unidades de Terapia Intensiva, devido à facilidade e segurança do método realizado à beira do leito, dispensando o transporte do paciente da Unidade de Terapia Intensiva para o Centro Cirúrgico. Alguns autores sugerem que a dissecção limitada resulta em menor dano tecidual, diminui o risco de sangramento e infecção de ferida operatória. Esta revisão visa analisar e sintetizar estudos prospectivos e randomizados, revisões sistemáticas e meta-análises, comparando a traqueostomia percutânea e traqueostomia convencional em pacientes adultos em Unidades de Terapia Intensiva.

  11. Fluoride treatment in corticosteroid induced osteoporosis.

    OpenAIRE

    Rejou, F; Dumas, R; Belon, C; Meunier, P J; Edouard, C

    1986-01-01

    Severe osteoporosis with multiple vertebral fractures occurred in two girls receiving prolonged high dose corticosteroids for relapsing dermatomyositis. Sodium fluoride, supplemented with calcium and vitamin D, helped control secondary osteoporosis in one case and should be considered as part of the curative treatment of corticoid induced osteoporosis.

  12. Prise en charge d'un cas de paralysie faciale périphérique du ...

    African Journals Online (AJOL)

    Treatment consists of a corticoids-based therapy involving the administration of high dosage of the latter, ocular protection, intense facial physiotherapy without electrical stimulation, coupled with cryotherapy and thermotherapy, which often result in the patient's complete recovery. Keywords: Facial peripheric paralysis, ...

  13. Melanotroph pituitary adenoma in a cat with diabetes mellitus

    NARCIS (Netherlands)

    Meij, B.P.; Vlugt-Meijer, R.H. van der; Ingh, T.S. van den; Flik, G.; Rijnberk, A.

    2005-01-01

    A 13-year-old male, castrated, crossbred cat was referred for insulin-resistant diabetes mellitus. The cat had a ravenous appetite and a dull coat. Basal urinary corticoid/creatinine ratios were normal. In the low-dose dexamethasone suppression test there was no suppression of the (nonelevated)

  14. Repeated blockade of mineralocorticoid receptors, but not of glucocorticoid receptors impairs food rewarded spatial learning

    NARCIS (Netherlands)

    Douma, B. R.; Korte, S. M.; Buwalda, B.; La Fleur, S. E.; Bohus, B.; Luiten, P. G.

    1998-01-01

    Corticosteroids from the adrenal cortex influence a variety of behaviours including cognition, learning and memory. These hormones act via two intracellular receptors, the mineralo-corticoid receptor (MR) and the glucocorticoid receptor (GR). These two receptor types display a high concentration and

  15. Repeated blockade of mineralocorticoid receptors, but not of glucocorticoid receptors impairs food rewarded spatial learning

    NARCIS (Netherlands)

    Douma, BRK; Korte, SM; Buwalda, B; la Fleur, SE; Bohus, B; Luiten, PGM

    Corticosteroids from the adrenal cortex influence a variety of behaviours including cognition, learning and memory. These hormones act via two intracellular receptors, the mineralo-corticoid receptor (MR) and the glucocorticoid receptor (GR). These two receptor types display a high concentration and

  16. Linfoma angioinmunoblástico de células T

    Directory of Open Access Journals (Sweden)

    Gargantilla P

    2016-09-01

    Full Text Available Se trata de un linfoma muy agresivo, con una mediana de supervivencia en torno a los 3 años. En cuanto al tratamiento, se han ensayado varias modalidades terapéuticas entre las cuales se encuentran los corticoides, los fármacos citotóxicos (vorinostat, romidepsin, panbinostat y belinostat y los inmunomoduladores (rituximab, lenalidomide.

  17. Disease: H01709 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available corticoids sensitivity has been suggested. The risks of this disease include advancing age, prolonged durati...on of treatment, increased daily dosage and cumulative dose, low body mass index, underlying disease, and po...MeSH: D005271 PMID:21732837 ... AUTHORS ... Weinstein RS ... TITLE ... Clinical practice. Glucocorticoid-induced bone dise

  18. Effects of G-Induced Stress on Pulmonary Circulation.

    Science.gov (United States)

    1976-12-01

    INTRODUCTION Previous studies have demonstrated that, in subjects, NI results in a significant and reproducible natriuresis and diuresis , and a...Epstein, M., J. L. Katsikas, and D. C. Duncan. Role of mineralo- corticoids in the natriuresis of water immersion in man. Circ Res 32:228-236 (1973). 15

  19. Shock in the Nonhuman Primate. Volume 2. Abstracts of the Published Literature, 1974-1977

    Science.gov (United States)

    1977-06-01

    primate. This study was, therefore, designed to answer the following questions: Do pharmacologic doses of gluco- corticoids protect the subhuman primate...metabolic changes, the GIK infusion reduced circulating FFA by about half, and increased diuresis . The only significant effect of GIK infusion on

  20. Fiebre y placas dolorosas en manos. ¿Cuál es el diagnóstico?

    Directory of Open Access Journals (Sweden)

    Juan Manuel Barja López

    2013-12-01

    Full Text Available Presentamos un caso de Síndrome de Sweet con lesiones cutáneas características, precipitado posiblemente por una infección respiratoria, que respondió satisfactoriamente a corticoides orales. Se realiza una brevísima descripción del síndrome basada en la literatura médica.

  1. Medical Treatment of Tattoo Complications.

    Science.gov (United States)

    Serup, Jørgen

    2017-01-01

    Tattooing is a skin trauma and involves a special vulnus punctatum (with inserted tattoo ink, a vulnus venenatum), which should heal with no infection and no local complication. Local treatment in the healing phase ideally builds on the 'moist wound' principle using plastic film, hydrocolloids, silver dressing, and compression. Bacterial infections during healing are treated with oral antibiotics, and a list of first-line antibiotics is proposed. Notice is given to severe infections with affected general condition, and it is emphasized that intravenous antibiotic treatment must be instituted as early as possible to prevent septic shock and death. Hydrophilic antibiotics shall be given in high load and maintenance dose due to increased renal clearance of such antibiotics. Chronic allergic reactions of red tattoos respond little to local corticoids and are best treated with dermatome shaving. Laser removal is contraindicated due to the risk of photochemical activation of the allergy with anaphylaxis or worsening. Chronic reactions in black tattoos can be treated with local corticoids, dermatome shaving, and lasers as well. Systemic corticoid is used in allergic reactions in red tattoos and in cross-allergic reactions of other red tattoos as well as in black tattoo reactions associated with sarcoidosis and with cutaneous 'rush phenomenon' affecting any black tattoo. Systemic corticoid is also indicated in generalized eczema due to nickel allergy or another allergy challenged through tattooing or introduced by tattooing as a primary sensitization. The use of intralesional corticoid, antihistamines, and immunosuppressive medicines is discussed. A warning against the use of lactic acid and other caustic chemicals for tattoo removal is given, since such chemicals and commercial products cannot be dosed properly and very often result in disfiguring scarring. © 2017 S. Karger AG, Basel.

  2. Marker-assisted improvement of the elite restorer line of rice, RPHR ...

    Indian Academy of Sciences (India)

    1032. Mishra B., Viraktamath B. C., Iyas Ahmed M., Ramesha M. S. and. Vijayakumar C. H. 2003 Hybrid rice research and development in India. In Hybrid rice for food security, poverty alleviation and environmental protection. Proceedings of the 4th International. Symposium on hybrid rice, Hanoi, Vietnam Los Banos (Philip-.

  3. Polymorphisms of candidate genes associated with meat quality and ...

    African Journals Online (AJOL)

    Hung Nguyen

    1 Institute of Biotechnology, Vietnam Academy of Science and Technology, Hanoi, Vietnam. 2 National Institute ... percentage of carcass and high-growth performance by making use of heterosis, mainly between indigenous and imported .... PCR-RFLP method using the restriction enzymes, MspI and HaeIII. Digestion of the ...

  4. A comparative study of faecal sludge management in Malawi and ...

    African Journals Online (AJOL)

    Rochelle Holm

    This review paper covers the issues of pit latrine emptying national policies and regulations with a focus on Malawi and Zambia. ... national policies and regulations taking faecal sludge management into account are weak and have wide gaps in the two study ...... Conference, Hanoi, Vietnam. Malawi Government (2004).

  5. Whole genome analysis of a Vietnamese trio

    Indian Academy of Sciences (India)

    We here present the first whole genome analysis of an anonymous Kinh Vietnamese (KHV) trio whose genomes were deeply sequenced to 30-fold average ... Wellcome Trust Center for Human Genetics, Oxford University, Oxford, UK; High Performance Computing Center, Hanoi University of Science and Technology, ...

  6. Utilizing the Active and Collaborative Learning Model in the Introductory Physics Course

    Science.gov (United States)

    Nam, Nguyen Hoai

    2014-01-01

    Model of active and collaborative learning (ACLM) applied in training specific subject makes clear advantage due to the goals of knowledge, skills that students got to develop successful future job. The author exploits the learning management system (LMS) of Hanoi National University of Education (HNUE) to establish a learning environment in the…

  7. Théâtre et Empire. Le théâtre français en Indochine pendant la Belle Époque (1890-1914)

    NARCIS (Netherlands)

    Kleinen, J.

    2014-01-01

    Theatre was mainly a European affair serving the European colonial groups who lived in Haiphong and Hanoi around the turn of the century. The influence of theBelle Epoque (1890-1914) in Indochina is marked by light entertainment brought to the colony by ambulant theater groups coming from France.

  8. Effects of Cross-Border Engineer Exchange on Innovation

    DEFF Research Database (Denmark)

    Machikita, Tomohiro

    2012-01-01

    Using data from a survey to manufacturing firms, this paper attempts to detect sources of new technologies transferred to a well-established industrial district in Calabarzon, the Philippines, and a rapidly growing agglomeration in Hanoi, Vietnam. We find significant effects of exchange of engine...

  9. Bullying the Meek: A Conceptualisation of Vietnamese School Bullying

    Science.gov (United States)

    Horton, Paul; Kvist Lindholm, Sofia; Nguyen, Thu Hang

    2015-01-01

    Drawing on ethnographic research conducted at three lower secondary schools in the northern Vietnamese cities of Hanoi and Haiphong, this article provides a contextually nuanced conceptualisation of Vietnamese school bullying. In doing so, the article not only addresses the lack of knowledge about Vietnamese school bullying, but also poses a…

  10. Arsenic in groundwater of the Red River Floodplain, Vietnam

    DEFF Research Database (Denmark)

    Postma, Diederik Jan; Larsen, Flemming; Jessen, Søren

    2007-01-01

    The mobilization of arsenic (As) to the groundwater was studied in a shallow Holocene aquifer on the Red River flood plain near Hanoi, Vietnam. Results show an anoxic aquifer featuring organic carbon decomposition with redox zonation dominated by the reduction of Fe-oxides and methanogenesis. The...

  11. Alcohol Brochure -Project List Oct 2016 ENGLISH.PUB

    International Development Research Centre (IDRC) Digital Library (Canada)

    fdieudonne

    Public health implications of alcohol industry corporate social responsibility programs The impact of price, tax, and advertising policies on alcohol use in Argentina, Bolivia, Chile, and Peru. (2013–2016, Universidad Adolfo Ibáñez). The international alcohol control study in Vietnam. (2013–16, Hanoi School of Public Health).

  12. Developing the Profession of School Psychology in Vietnam

    Science.gov (United States)

    Terjesen, Mark D.; Kassay, Kimberly S.; Bolger, Maria

    2008-01-01

    Building upon a successful prior initial trip to Vietnam in January 2008, students and faculty from St. John's University (STJ) School Psychology program returned to work with the faculty from Hanoi National University of Education (HNUE) in developing the profession of school psychology in that country. The purpose of this trip was twofold: (1)…

  13. Returning to Vietnam – Building on Collaborations in Cancer Control and Research

    Science.gov (United States)

    Dr. Paul Pearlman presented at the 9th US-Vietnam Joint Committee Meeting on Science and Technology Cooperation, held in Ho Chi Minh City by the Ministry of Science and Technology, and at a national cancer stakeholder meeting in Hanoi, held by the Ministry of Health.

  14. 1 RESEARCH ARTICLE

    Indian Academy of Sciences (India)

    Navya

    2017-03-13

    Mar 13, 2017 ... Genetic analysis of 55 Northern Vietnamese patients with Wilson disease: 7 novel mutations in ATP7B .... All WD patients were diagnosed and treated at the National Pediatrics Hospitalin Hanoi from ... acute or chronic liver failure and/or typical neurological symptoms, or the presence of Kayser-. Fleischer ...

  15. On the Competition Problems of IPhO 39 in Vietnam

    Science.gov (United States)

    Khoi, Nguyen The; Tu, Pham Quy; Don, Dam Trung

    2009-01-01

    We report on the competition problems given at the 39th International Physics Olympiad held in Hanoi, Vietnam, which consist of three theoretical and one experimental problems. The abbreviated solutions are presented. The distribution of marks for the problems is also shown. (Contains 2 tables and 8 figures.)

  16. Hygienic aspects of livestock manure management and biogas systems operated by small-scale pig farmers in Vietnam

    DEFF Research Database (Denmark)

    Luu, Huong Quynh; Madsen, Henry; Anh, Le Xuan

    2014-01-01

    ) and to assess fecal contamination levels in biogas effluent. Results showed that 84% of the farmers in Hanoi and 42% in Hue used both pig slurry and human excreta for biogas production. Biogas digestion only reduced E. coli concentrations by 1 to 2 log units to 3.70±0.84 Escherichia coli (log) cfu/ml on average...

  17. Immunological studies on Ascaris suum infections in mice

    NARCIS (Netherlands)

    Phan van Than*; Knapen; F.van

    1986-01-01

    Het betreft een rapportage van onderzoek dat werd verricht door Dr.Phan van Than, Instituut voor Parasitologie, Medische Faculteit Hanoi, Vietnam. Dr.Than heeft zich in het bijzonder bezig gehouden met het toetsen van verschillende antigenen afkomstig van Ascaris suum en Ascaris lumbricoides

  18. Effectiveness of a multi-component intervention on dispensing practices at private pharmacies in Vietnam and Thailand--a randomized controlled trial.

    Science.gov (United States)

    Chalker, J; Ratanawijitrasin, S; Chuc, N T K; Petzold, M; Tomson, G

    2005-01-01

    Private pharmacies are the first line of health care in many communities, commonly selling antibiotics in small doses and prescription-only drugs such as steroids without medical supervision. The aim was to study the effectiveness of a multi-faceted intervention on the dispensing practices of drug sellers in Hanoi and Bangkok. The study was a randomized, controlled trial with 68 Hanoi and 78 Bangkok pharmacies, randomly selected and assigned for intervention and control. Behaviour was assessed by five simulated client visits per pharmacy per dispensing practice, at baseline and a month or more after each intervention. Three three-month interventions were implemented sequentially with four months in between: enforcement of regulations with local inspectors visiting to emphasize the importance of prescription-only medicine legislation; education, performed face-to-face in Hanoi and by a large group in Bangkok; and peer review, voluntary in Bangkok and compulsory in Hanoi. The intervention resulted in significant improvements in Hanoi, reducing the dispensing of illegal steroids (29% vs. 62%) and low dose antibiotics (69% vs. 90%), sustained by means of the peer review (17% vs. 57% steroids and 71% vs. 95% antibiotics), and in fewer dispensers asking no questions and giving no advice (11% vs. 30% steroids and 51% vs. 81% antibiotics). The only significant improvement in Bangkok was the reduction in illegally dispensing steroids (25% vs. 44%) after the regulatory intervention. In Bangkok, fewer of those in the group who volunteered for the peer review asked no questions and gave no advice for low-dose antibiotics requests after the peer review (58% vs. 81%). A multi-component intervention can have a profound effect in changing dispensers' behaviour, but the effect is dependant on the context and the method of implementation. Possible reasons for differences are discussed.

  19. [Complications of colonic diverticular disease during rheumatoid polyarthritis: 7 cases].

    Science.gov (United States)

    Durieux, S; Rozenberg, S; Bourgeois, P

    1999-01-01

    Among the gastrointestinal adverse effects of nonsteroidal anti-inflammatory drugs (NSAID) and corticoids are mentioned complications of colonic diverticular disease. However, very few studies have described their consequences in rheumatoid arthritis. We report on seven patients who were admitted in our department between 1984 and 1997. All patients received corticoids and another antirheumatic drug (gold salts, hydroxychloroquine, immunosuppressive drugs); treatment also included NSAID in four cases. Two patients had a necrotizing vasculitis accompanying rheumatoid arthritis. Intestinal accompanying diseases were the following: one diverticulitis, three colonic perforations with pelviperitonitis, one colovesical fistula, one pelvic abscess, and one diverticular hemorrhage. All patients underwent surgery with positive results. Combination of the four following symptoms: fever, abdominal pain, diarrhea, and hemorrhage, can uncover a complication of colónic diverticular disease occurring in the course of rheumatoid arthritis. It should be investigated, even if no history of diverculosis may be evidenced.

  20. Lesões bolhosas palmo-plantares pós-quimioterapia

    Directory of Open Access Journals (Sweden)

    Mário Pires

    2013-09-01

    Full Text Available Apresentamos um caso de um doente com o diagnóstico de sarcoma pulmonar que, após o 3º ciclo de tratamento com doxorrubicina lipossómica pegilada (DLP (50mg/m2 cada 4 semanas, desenvolveu exuberantes lesões bolhosas, descamativas, nas palmas das mãos, (Figuras 1 e 2, e plantas dos pés, com impotência funcional total. Efetuouse tratamento com corticoide sistémico e aplicação tópica de antibiótico, corticoide e hidratantes. Após duas semanas a melhoria em termos de dor e capacidade funcional foram substanciais (Figuras 3 e 4. Devido à severidade deste episódio, nos tratamentos subsequentes a DLP foi substituída por trabectidina.

  1. Is epidural steroid injection effective for degenerative lumbar spinal stenosis?

    Directory of Open Access Journals (Sweden)

    Sebastián Flores

    2015-12-01

    Full Text Available Existe una variada cantidad de alternativas no quirúrgicas para tratar el dolor radicular producido por la raquiestenosis lumbar degenerativa. Los corticoides epidurales se utilizan desde hace varias décadas, sin embargo la eficacia reportada en la literatura es muy variable. Utilizando la base de datos Epistemonikos, la cual es mantenida mediante búsquedas en 30 bases de datos, identificamos nueve revisiones sistemáticas que en conjunto incluyen siete estudios aleatorizados. Realizamos un metanálisis y tablas de resumen de los resultados utilizando el método GRADE. Concluimos que la inyección de corticoides epidurales probablemente tiene poco o nulo efecto en reducir el dolor radicular por estenorraquis.

  2. High-dose inhaled corticosteroids or addition of theophylline in patients with poorly controlled asthma?

    Directory of Open Access Journals (Sweden)

    Pilar Celis

    2015-08-01

    Full Text Available Existen varias estrategias para el manejo de los pacientes asmáticos con mal control a pesar del tratamiento habitual. Dentro de las alternativas terapéuticas se encuentra aumentar las dosis de corticoides inhalados o utilizar teofilina. Sin embargo, esta última se asocia a importantes efectos adversos. Utilizando la base de datos Epistemonikos, la cual es mantenida mediante búsquedas en 30 bases de datos, identificamos una revisión sistemática que incluye cuatro estudios aleatorizados. Realizamos un metanálisis y tablas de resumen de los resultados utilizando el método GRADE. Concluimos que no está claro si teofilina o el uso de dosis altas de corticoides inhalados logran un mejor control sintomático o reducción de las exacerbaciones en pacientes asmáticos no controlados porque la certeza de la evidencia es muy baja.

  3. Methylprednisolone sodium succinate in pediatric parenteral nutrition: influence of vehicle injection.

    Science.gov (United States)

    Gellis, Christophe; Sautou-Miranda, Valérie; Jarrige, Jean-François; Grand-Boyer, Anne; Bleyzac, Nathalie; Chopineau, Jean

    2004-08-01

    Many drugs can be administered in parenteral nutrient mixtures, but no work on the delivery of corticoids by such means is reported. We studied the influence of pediatric parenteral nutrient mixtures on the kinetic parameters of the corticoid methylprednisolone injected in an intravenous bolus in rabbits as its sodium succinate ester. Four groups of six male New Zealand rabbits were used. After extraction, the plasma drug concentrations were measured by high performance liquid chromatography. The distribution volume of the ester and the clearance rates of the two entities (ester and methylprednisolone) were lowered in the presence of a lipid emulsion. The description of these pharmacokinetic parameters provides a basis for a preclinical study of 24h administration of methylprednisolone in a parenteral nutrient mixture. Copyright 2003 Elsevier Ltd.

  4. Lumbar spine joint synovial cysts of intraspinal development. CT scan imaging

    Energy Technology Data Exchange (ETDEWEB)

    Vallee, C.; Chevrot, A.; Benhamouda, M. and others

    CT scan imaging findings are described in 22 patients with lumbar spine joint synovial cysts, of intraspinal development, provoking sciatica or lumbosciatica from nerve compression in spinal canal. Diagnosis was suggested by a mass at the posterior joint level, of variable density, sometimes with peripheral calcification, presenting a vacuum appearance on occasions, and with enhanced image with contrast. Differential diagnosis is from excluded hernia and postoperative fibrosis. Posterior intra-articular arthrography can confirm diagnosis and allow treatment with prolonged action corticoid infiltrations.

  5. Fecal corticosterone excretion in captive healthy and feather picking African grey parrots (Psittacus erithacus)

    OpenAIRE

    Costa, Pierluca; Macchi, Elisabetta; Valle, Emanuela; De Marco, Michele; Gasco, Laura; Schiavone, Achille

    2016-01-01

    Feather picking (FP) is a common problem in companion parrots, especially in African grey parrots (Psittacus erithacus). Many hypothesis have been made about this self-mutilating behavior, and serious psychological conflicts can play a pivotal role in the initiation of this self-defeating and self-punishing behaviour. Even though ethological distress is difficult to study, the monitoring of fecal corticoids is a useful non-invasive tool that can be used to assess stress in animals. The purpos...

  6. Inmunogenicidad de la vacuna frente al virus de la hepatitis B en pacientes con enfermedad inflamatoria intestinal

    OpenAIRE

    Olsen Rodríguez, Renée

    2017-01-01

    La colitis ulcerosa (CU) y la enfermedad de Crohn (EC) son patologías que se denominan conjuntamente enfermedad inflamatoria intestinal (EII). Su patogenia es poco conocida, pero si se sabe que hay una respuesta inmune frente a estructuras del tubo digestivo. El tratamiento se basa es disminuir esta inmunogenicidad administrando corticoides, inmunosupresores o terapias biológicas. Todas estas circunstancias favorecen las infecciones y reactivaciones por el virus de la hepatitis B (VHB). La pr...

  7. Physiological indicators of stress in gestating sows under different cooling systems Indicadores fisiológicos de estresse em porcas gestantes sob diferentes sistemas de refrigeração

    Directory of Open Access Journals (Sweden)

    José Quiñonero

    2009-11-01

    Full Text Available The objective of this work was to determine physiological stress markers, neutrophil:lymphocyte ratio (N/L and corticoid concentrations, in gestating sows under different cooling systems. A sprinkling cooling system (SS and a system based on fan-assisted evaporative cellulose pad (PS were used. SS showed higher N/L ratio (1.095 than PS (0.850. Corticoid concentrations showed high variability. Corticosteroids are more efficient short-term stress indicators while N/L ratio is a good medium and long-term stress indicator. According to N/L ratio, gestating sows under PS benefit from a higher level of welfare.O objetivo deste trabalho foi determinar os marcadores fisiológicos de estresse, a razão entre neutrófilos e linfócitos (N/L e as concentrações de corticoides em porcas gestantes submetidas a diferentes sistemas de refrigeração. Foram utilizados um sistema de refrigeração com aspersores (SS e um sistema baseado em painel evaporativo de celulose com ventilador (PS. O SS apresentou maior proporção N/L (1,095 que o PS (0,850. As concentrações de corticoides tiveram alta variabilidade. Os corticoesteroides são indicadores de estresse mais eficientes em curto prazo, enquanto a proporção N/L é um bom indicador de estresse em médio e longo prazo. De acordo com a proporção N/L, as porcas gestantes submetidas ao PS se beneficiaram de maior bem-estar.

  8. Space Flight Research Relevant to Health, Physical Education, and Recreation. With Particular Reference to Skylab’s Life Science Experiments

    Science.gov (United States)

    1979-06-01

    nitrogen, calcium, and other electrolytes; in- creased inflight adrenal hormone secretion; and no inflight diuresis (refs. I-8, 1-11, 1-12, and I...were proportional to body weight losses. No changes indicative of altered calcium were observed. Decreases were noted in glucocorticoids , possibly...se- creted by the anterior pituitary. Activates the adrenal in stress. Adrenal corticoids. Secretions of adrenal cor- tex, glucocorticoids , or

  9. Physiological Design Goals and Proposed Thermal Limits for U.S. Navy Thermal Garments: Proceedings of Two Conferences Sponsored by the Naval Medical Research and Development Command

    Science.gov (United States)

    1991-11-01

    effects of shivering, then some important secondary effects of cold and water immersion -- diuresis and dehydration -- and the interaction of cold with...acids, and increased blood lactates. One would also expect indicators of generalized stress change, such as corticoids in blood and urine. Secondary...underwater operations. It may be produced by diuresis , by a lack of ingested water, and by loss of water through evaporation from the respiration of

  10. Proposed Thermal Limits for Divers

    Science.gov (United States)

    1984-07-01

    recommended minimum inspired gas temperature as a function of depth, or pressure of the respired gas. Braithwaite, 1972. 4 m ersion ( diuresis and...levels of indicators of generalized stress, such as corticoids and catecholamines in blood and a greater urine content of such substances or their...stress that can be limiting io. underwater operations. it may be produced by diuresis , by a lack of ingest I water, or by a loss of water through

  11. Healing action of topical chamomile on 5-fluoracil induced oral mucositis in hamster.

    Science.gov (United States)

    Pavesi, Vanessa C S; Lopez, Talita C C; Martins, Marco A T; Sant'Ana Filho, Manoel; Bussadori, Sandra K; Fernandes, Kristianne P S; Mesquita-Ferrari, Raquel A; Martins, Manoela D

    2011-05-01

    Oral mucositis is a common complication in the treatment of cancer. Its management and prevention are seen as high priority in cancer patient care. The aim of the present study was to investigate the effect of topical chamomile in the treatment of oral mucositis induced by 5-fluoracil (5-FU) in hamsters. One hundred five hamsters were randomly separated into three groups (35 animals each): group I--without treatment (control); group II--treatment with chamomile (Ad-Muc®); and group III--treatment with corticoid (betamethasone elixir--Celestone®). The animals received an intraperitoneal injection of 5-FU on days 0 and 2. On days 3 and 4, the buccal mucosa was scratched and therapy was initiated on day 5. Three animals were sacrificed on days 0, 2, 5, 8, 10, 12, 14, and 16, weighed, and the buccal mucosa removed for clinical and histopathological analysis. The animals that developed mucositis and were treated with chamomile or the corticoid agent weighed significantly less than those in the control group. The group treated with the corticoid agent exhibited a more severe clinical condition, whereas the group treated with chamomile exhibited mild mucositis throughout the experiment. The group treated with chamomile had a 12-fold greater chance of scoring zero (absence of mucositis) than the control group. Analysis of the histopathological results demonstrated that the group treated with chamomile exhibited a lesser degree of mucositis throughout the evaluation period in comparison to the control and corticoid groups. Chamomile proved effective in the treatment of oral mucositis in a hamster model. However, well-designed clinical studies are needed to confirm the clinical efficacy of this medicine in humans.

  12. Tinea incognito due to Trichophyton mentagrophytes: case report

    Directory of Open Access Journals (Sweden)

    Walter Gubelin

    2016-11-01

    Full Text Available Resumen Las tiñas son infecciones frecuentes causadas por dermatofitos, capaces de invadir tejido queratinizado, produciendo placas anulares, eritematosas y descamativas. Sin embargo, en la tiña incógnita esta clínica es modificada por el uso inapropiado de corticoides o inhibidores de calcineurina tópicos, dificultando su diagnóstico. Presentamos el caso de un paciente masculino de 12 años, con lesiones eritematosas localizadas en la región ciliar derecha. Se interpretó como una dermatitis de contacto y se indicaron corticoides tópicos, pero evolucionó con lesiones más inflamatorias. Se obtuvo un cultivo de hongos positivo para Tricophyton mentagrophytes. De este reporte se concluye que las tiñas pueden imitar otras condiciones dermatológicas. Por ende, se debe tener precaución al indicar corticoides o inhibidores de calcineurina tópicos sin una certeza diagnóstica. Ello, debido a que en el caso de corresponder a una tiña, se alteran las características clínicas, dificultando el diagnóstico y manejo.

  13. [Management of immune suppression in systemic diseases affecting the kidney].

    Science.gov (United States)

    Ballarín, J; Díaz, M

    2008-01-01

    We reviewed the literature in 2007 on 3 groups of systemic diseases affecting the kidney: lupic nephropathy (LN), small vessel vasculitis (SVV) and renal amyloidosis. A systematic review of 268 patients with LN pooled from 4 studies found that mycophenolic acid (MPA) in the induction phase caused more remissions and achieved greater renal survival than cyclophosphamide (CP), confirming it as a valid alternative to CP. Using a protocol including rituximab and MPA in the induction phase (14 days), MPA alone without corticoids is effective and safe in the maintenance phase. Rituximab has also been successfully used in CP-resistant forms of LN, where it reduces clinical activity and mesangial proliferation. Plasma exchanges achieve better results than bolus corticoids in SVS with severe renal failure. Complications are severe. Anti- TNF-alpha agents provide no benefit in this indication. Prolonged administration of low-dose corticoids reduces the incidence of relapses. MPA is an alternative to CP if this drug cannot be administered. Good results are achieved with rituximab in CP-resistant forms. According to a controlled trial, treatment of AL amyloidosis with dexamethasone and melphalan has equivalent results to highdose melphalan and rescue with hematopoietic stem cell transplant. In AA amyloidosis, eprosidate slows the rate of progression of renal failure.

  14. (Mis)use of Prescribed Stimulants in the Medical Student Community: Motives and Behaviors: A Population-Based Cross-Sectional Study.

    Science.gov (United States)

    Fond, Guillaume; Gavaret, Martine; Vidal, Christophe; Brunel, Lore; Riveline, Jean-Pierre; Micoulaud-Franchi, Jean-Arthur; Domenech, Philippe

    2016-04-01

    The aim of this study was to estimate the prevalence of psychostimulant use in the French medical community and their motives. A population-based cross-sectional study using a self-administered online survey was done. A total of 1718 French students and physicians (mean age, 26.84±7.19 years, 37.1% men) were included. Self-reported lifetime use, motives, socio-demographic and academic features for over the counter (OTC), medically prescribed (MPP), and illicit (IP) psychostimulant users were reported. Lifetime prevalence of psychostimulant use was 33% (29.7% for OTC, 6.7% for MPP, and 5.2% for IP). OTC consumption mainly aimed at increasing academic performance and wakefulness during competitive exams preparation. OTC consumption started early and was predictive of later MPP use. Corticoids were the most frequently consumed MPP (4.5%) before methylphenidate and modafinil. Motives for MPP consumption were increased academic performance, concentration, memory, and wakefulness. Psychostimulant use is common among French medical community. Our results suggest that restrictions on methylphenidate and modafinil prescriptions are effective at limiting their use. However, these restrictions may explain the observed rates of corticoids consumption, which raise a new public health problem, given that corticoids may have severe side effects.

  15. 3rd International Conference on High Performance Scientific Computing

    CERN Document Server

    Kostina, Ekaterina; Phu, Hoang; Rannacher, Rolf

    2008-01-01

    This proceedings volume contains a selection of papers presented at the Third International Conference on High Performance Scientific Computing held at the Hanoi Institute of Mathematics, Vietnamese Academy of Science and Technology (VAST), March 6-10, 2006. The conference has been organized by the Hanoi Institute of Mathematics, Interdisciplinary Center for Scientific Computing (IWR), Heidelberg, and its International PhD Program ``Complex Processes: Modeling, Simulation and Optimization'', and Ho Chi Minh City University of Technology. The contributions cover the broad interdisciplinary spectrum of scientific computing and present recent advances in theory, development of methods, and applications in practice. Subjects covered are mathematical modelling, numerical simulation, methods for optimization and control, parallel computing, software development, applications of scientific computing in physics, chemistry, biology and mechanics, environmental and hydrology problems, transport, logistics and site loca...

  16. 6th International Conference on Knowledge and Systems Engineering

    CERN Document Server

    Le, Anh-Cuong; Huynh, Van-Nam

    2015-01-01

    This volume contains papers presented at the Sixth International Conference on Knowledge and Systems Engineering (KSE 2014), which was held in Hanoi, Vietnam, during 9–11 October, 2014. The conference was organized by the University of Engineering and Technology, Vietnam National University, Hanoi. Besides the main track of contributed papers, this proceedings  feature the results of four special sessions focusing on specific topics of interest and three invited keynote speeches. The book gathers a total of 51 carefully reviewed papers describing recent advances and development on various topics including knowledge discovery and data mining, natural language processing, expert systems, intelligent decision making, computational biology, computational modeling, optimization algorithms, and industrial applications.

  17. Worldwide Report, Telecommunications Policy, Research, and Development

    Science.gov (United States)

    1985-12-06

    34 carries news, variety shows, Soviet films or foreign movies dubbed in Russian, and a lot of sports. Hanoi football fans can tune in to most major...POLICY, RESEARCH AND DEVELOPMENT CONTENTS ASIA HONG KONG Cable and Wlreless-MCI Pact To Boost U.S. Phone Calls (Hong Kong HONGKONG STANDARD, 9...GUARDIAN, 23 Oct 85) 44 NEAR EAST/SOUTH ASIA INDIA Parliament Panel Urges National Broadcasting Policy (Calcutta THE SUNDAY STATESMAN, 15 Sep 85

  18. A Matched Case-Control Study of Risk Factors for Breast Cancer Risk in Vietnam

    OpenAIRE

    Nguyen, J.; Le, Q. H.; Duong, B. H.; Sun, P.; Pham, H. T.; Ta, V. T.; Kotsopoulos, J.; Narod, S. A.; Ginsburg, O.

    2016-01-01

    Background. Vietnam has a low age-standardized incidence of breast cancer, but the incidence is rising rapidly with economic development. We report data from a matched case-control study of risk factors for breast cancer in the largest cancer hospital in Vietnam. Methods. 492 incident breast cancer cases unselected for family history or age at diagnosis and 1306 control women age 25–75 were recruited from the National Cancer Hospital (BVK), Hanoi. Structured interviews were conducted and path...

  19. Rebalance to Asia and the Pacific: Leveraging Vietnam to Counter-Balance China

    Science.gov (United States)

    2016-06-10

    essential according to Timothy Beardson. Beardson looked at Vietnam as one of the key Asian countries that can provide some needed friction against...bolster its position against an unpredictable China, especially in light of recent friction between Vietnam and China in the South China Sea, “Hanoi has...exists a need for land base defense equipment such as armored personnel carriers, tanks, artillery, radar, rotary wing aircraft, and air defense missiles

  20. Vietnam: A Failure of Strategy and Leadership

    Science.gov (United States)

    2013-04-30

    boundaries set by civilian leadership . Likewise, it also presents a case study in the absolute necessity for military leaders to address policy limitations ...but was within limitations set by civilian leadership . Likewise it would have been incumbent upon General Westmoreland to analyze what he was... limited approach by communist leadership in Hanoi where the stated objected was a unified Vietnam. Nixon and his team immediately initiated planning to

  1. Quality Management for Public Transport in Motorcycle Dependent Cities

    OpenAIRE

    An, Minh Ngoc

    2015-01-01

    In many cities of Asian countries, urban transport system is held by motorcycle. For example, motorcycle accounted for more than 65 percent of the total modal share in Hanoi and Hochiminh City (HCMC). This influences not only land use pattern of the cities (for example this causes growing of motorcycle-based land uses) but also traveller’s behaviour (people in Motorcycle Dependent Cities - MDCs do not have much motivation of shifting to travelling by bus instead of motorcycle). The lack o...

  2. Toward an Anthropology of the Imaginary: Specters of Disability in Vietnam

    National Research Council Canada - National Science Library

    Gammeltoft, Tine M

    2014-01-01

    ....” Drawing on nearly three years of fieldwork conducted in Vietnam's capital Hanoi, I frame selective reproduction as an issue of power and politics, investigating how people's fantasies, fears, and imaginings blend with the workings of state power in this realm. Attention to imaginary constructions of self and society, I argue, can further anthropological understanding of the ways in which state policies are shaped, implemented, justified, and received.

  3. Mettiamoci in gioco

    OpenAIRE

    Matassi, Elisabetta; Curci, Emma

    2012-01-01

    Il laboratorio qui descritto introduce gli elementi fondamentali della teoria dei giochi e delle decisioni attraverso lo studio di alcuni tra i più interessanti giochi d’ingegno (tra questi: Le Torri di Hanoi, Burr esagonale, Quattro in riga, Labirinto tridimensionale). Iniziando dall’osservazione e dalla manipolazione di un modello tridimensionale in legno, gli allievi sono stati sollecitati a mettersi alla prova, giocando contro un avversario o contro se stessi. Partendo da u...

  4. 2650-IJBCS-Article-Tapsoba Fidèle Wend Benedo

    African Journals Online (AJOL)

    hp

    results that, water from the dam of good quality from the physicochemical stand point and covers with the ..... *Normes nationales sur la qualité des eaux potabilisables par degré de pollution (décret n°2001-185 /PRES/PM/MEE portant fixation des normes de rejets de polluants dans l'air, .... Dans Actes des JSIRAUF, Hanoi,.

  5. Motivation for smoking cessation among drug-using smokers under methadone maintenance treatment in Vietnam

    OpenAIRE

    Tran, Bach Xuan; Nguyen, Long Hoang; Do, Huyen Phuc; Nguyen, Nhung Phuong Thi; Phan, Huong Thu Thi; Dunne, Michael; Latkin, Carl

    2015-01-01

    Background Smoking cessation treatment service is concerned to be a critical element in methadone maintenance treatment (MMT) in order to diminish the effect of smoke on health outcomes. To implement the smoking cessation services in Vietnam, we examined the stages of change to quit and determined associated factors among MMT patients. Methods We conducted a cross-sectional survey with 1016 MMT patients in five clinics in Hanoi and Nam Dinh province, of those, 932 (91.7?%) were ever-smokers. ...

  6. Helicobacter pylori infection and gastroduodenal diseases in Vietnam: a cross-sectional, hospital-based study.

    Science.gov (United States)

    Nguyen, Tung L; Uchida, Tomohisa; Tsukamoto, Yoshiyuki; Trinh, Dung T; Ta, Long; Mai, Bang H; Le, Song H; Thai, Ky D; Ho, Dung D; Hoang, Hai H; Matsuhisa, Takeshi; Okimoto, Tadayoshi; Kodama, Masaaki; Murakami, Kazunari; Fujioka, Toshio; Yamaoka, Yoshio; Moriyama, Masatsugu

    2010-09-30

    The rate of H. pylori infection in Vietnam is reportedly high, but the spectrum of H. pylori-associated gastroduodenal diseases has not been systematically investigated. Moreover, despite the similarities of ethnicity and diet, the age-standardized incidence rate of gastric cancer in the northern city of Hanoi is higher than that in the southern city of Ho Chi Minh, but the reason for this phenomenon is unknown. The virulence of Vietnamese H. pylori has also not been investigated in detail. Individuals undergoing esophagogastroduodenoscopy were randomly recruited. H. pylori infection status was determined based on the combined results of culture, histology, immunohistochemistry, rapid urine test and serum ELISA. Peptic ulcer (PU) and gastroesophageal reflux disease was diagnosed by endoscopy, and chronic gastritis was determined histologically. H. pylori virulence factors were investigated by PCR and sequencing. Among the examined patients, 65.6% were infected with H. pylori. The prevalence of infection was significantly higher in those over 40 years of age than in those aged ≤40. Chronic gastritis was present in all H. pylori-infected individuals, 83.1% of whom had active gastritis, and 85.3% and 14.7% had atrophy and intestinal metaplasia, respectively. PU was present in 21% of infected patients, whereas its incidence was very low in non-infected individuals. The prevalence of PU was significantly higher in Hanoi than in Ho Chi Minh. The prevalence of vacA m1, which has been identified as an independent risk factor for PU in Vietnam, was significantly higher among H. pylori isolates from Hanoi than among those from Ho Chi Minh. H. pylori infection is common in Vietnam and is strongly associated with PU, active gastritis, atrophy and intestinal metaplasia. vacA m1 is associated with an increased risk for PU and might contribute to the difference in the prevalence of PU and gastric cancer between Hanoi and Ho Chi Minh.

  7. Vitellibacter nionensis sp. nov., isolated from shallow water hydrothermal vent of Espalamaca, Azores.

    Digital Repository Service at National Institute of Oceanography (India)

    Rajasabapathy, R.; Mohandass, C.; Yoon, J.-H.; Dastager, S.G.; Liu, Q.; Khieu, T.-N.; Son, C.K.; Li, W.-J.; Colaco, A.

    5School of Biotechnology and Food Technology, Hanoi University of Science and Technology, Vietnam 6IMAR-Centre of IMAR of the University of the Azores/ Department of Oceanography and Fisheries and LARSyS Associated Laboratory, Rua Prof Frederico.... (1984). Briefly, Polar lipids were extracted from freeze-dried cells and separated by two dimensional silica gel thin layer chromatography (Merck). The first direction was developed in chloroform/methanol/water (65:25:3.8, by vol.) and the second...

  8. World Epidemiology Review, Number 109.

    Science.gov (United States)

    1978-10-11

    development schemes and Orang Asli settlements," Dr. Ezad- din’ said. He said the main ob- jective of the program- me was not the elimina- tion of...Plague Outbreak Under Control 16 16 16 17 LAOS Briefs Antimalaria Workers Trained 18 MALAYSIA Tremendous Decline in Malaria Cases 19...who suffered malaria have treated adequately. [sentence as received] [Text] Hanoi KPL in English 0907 GMT 7 Sep 78 BK] CSO: 5400 18 MALAYSIA

  9. Helicobacter pylori infection and gastroduodenal diseases in Vietnam: a cross-sectional, hospital-based study

    Science.gov (United States)

    2010-01-01

    Background The rate of H. pylori infection in Vietnam is reportedly high, but the spectrum of H. pylori-associated gastroduodenal diseases has not been systematically investigated. Moreover, despite the similarities of ethnicity and diet, the age-standardized incidence rate of gastric cancer in the northern city of Hanoi is higher than that in the southern city of Ho Chi Minh, but the reason for this phenomenon is unknown. The virulence of Vietnamese H. pylori has also not been investigated in detail. Methods Individuals undergoing esophagogastroduodenoscopy were randomly recruited. H. pylori infection status was determined based on the combined results of culture, histology, immunohistochemistry, rapid urine test and serum ELISA. Peptic ulcer (PU) and gastroesophageal reflux disease was diagnosed by endoscopy, and chronic gastritis was determined histologically. H. pylori virulence factors were investigated by PCR and sequencing. Results Among the examined patients, 65.6% were infected with H. pylori. The prevalence of infection was significantly higher in those over 40 years of age than in those aged ≤40. Chronic gastritis was present in all H. pylori-infected individuals, 83.1% of whom had active gastritis, and 85.3% and 14.7% had atrophy and intestinal metaplasia, respectively. PU was present in 21% of infected patients, whereas its incidence was very low in non-infected individuals. The prevalence of PU was significantly higher in Hanoi than in Ho Chi Minh. The prevalence of vacA m1, which has been identified as an independent risk factor for PU in Vietnam, was significantly higher among H. pylori isolates from Hanoi than among those from Ho Chi Minh. Conclusions H. pylori infection is common in Vietnam and is strongly associated with PU, active gastritis, atrophy and intestinal metaplasia. vacA m1 is associated with an increased risk for PU and might contribute to the difference in the prevalence of PU and gastric cancer between Hanoi and Ho Chi Minh. PMID

  10. Helicobacter pylori infection and gastroduodenal diseases in Vietnam: a cross-sectional, hospital-based study

    Directory of Open Access Journals (Sweden)

    Okimoto Tadayoshi

    2010-09-01

    Full Text Available Abstract Background The rate of H. pylori infection in Vietnam is reportedly high, but the spectrum of H. pylori-associated gastroduodenal diseases has not been systematically investigated. Moreover, despite the similarities of ethnicity and diet, the age-standardized incidence rate of gastric cancer in the northern city of Hanoi is higher than that in the southern city of Ho Chi Minh, but the reason for this phenomenon is unknown. The virulence of Vietnamese H. pylori has also not been investigated in detail. Methods Individuals undergoing esophagogastroduodenoscopy were randomly recruited. H. pylori infection status was determined based on the combined results of culture, histology, immunohistochemistry, rapid urine test and serum ELISA. Peptic ulcer (PU and gastroesophageal reflux disease was diagnosed by endoscopy, and chronic gastritis was determined histologically. H. pylori virulence factors were investigated by PCR and sequencing. Results Among the examined patients, 65.6% were infected with H. pylori. The prevalence of infection was significantly higher in those over 40 years of age than in those aged ≤40. Chronic gastritis was present in all H. pylori-infected individuals, 83.1% of whom had active gastritis, and 85.3% and 14.7% had atrophy and intestinal metaplasia, respectively. PU was present in 21% of infected patients, whereas its incidence was very low in non-infected individuals. The prevalence of PU was significantly higher in Hanoi than in Ho Chi Minh. The prevalence of vacA m1, which has been identified as an independent risk factor for PU in Vietnam, was significantly higher among H. pylori isolates from Hanoi than among those from Ho Chi Minh. Conclusions H. pylori infection is common in Vietnam and is strongly associated with PU, active gastritis, atrophy and intestinal metaplasia. vacA m1 is associated with an increased risk for PU and might contribute to the difference in the prevalence of PU and gastric cancer between

  11. La politique d’éclairage public à Hà-Nội : Jeux d’acteurs et enjeux urbains

    OpenAIRE

    Luong Thi, Ngoc Huyen

    2012-01-01

    Thanks to the policy of "Doi moi", urban development in Vietnam in general and the evolution of urban lighting in particular have achieved considerable results. Some cities in Vietnam have been successful in creating an urban identity through their lighting policy. However, the lighting in the capital Hanoi, a city highly appreciated for its riches in cultural and architectural heritages, has not created any good impression. Especially, the lighting during the Millennium celebrations was such...

  12. Massively multiplayer online role-playing games (MMORPG): association between its addiction, self-control and mental disorders among young people in Vietnam.

    Science.gov (United States)

    Son, Dinh Thai; Yasuoka, Junko; Poudel, Krishna C; Otsuka, Keiko; Jimba, Masamine

    2013-09-01

    To explore the association between MMORPG addiction and mental health status, and between self-control ability and mental health status among young male MMORPG players in Hanoi, Vietnam. In this cross-sectional study, 10 computer game rooms were randomly selected out of 77 in five communes in Hanoi. From these game rooms, 350 MMORPG players were purposively recruited as a study group, of whom 344 completed the questionnaire. In the same five communes, 344 non-players were selected as a control group. An online game addiction scale, a self-control scale and the Vietnamese SRQ-20 were used to measure the degree of MMORPG addiction, self-control ability and level of mental disorders. MMORPG players had significantly higher mental disorders scale scores than non-players (p MMORPG addiction scale scores and mental disorders scale scores (r = 0.730, p MMORPG addiction scale score and self-control scale score were considered the best predictors of a higher mental disorders scale score. Young, male MMORPG players with higher addiction scores were more likely to have higher mental disorders scale scores, and such mental status was negatively associated with the level of self-control in Hanoi, Vietnam. Closer attention should be paid to prevent mental disorders among MMORPG players.

  13. [Effect of methylphenidate on executive function for children with attention deficit hyperactivity disorder].

    Science.gov (United States)

    Shuai, Lan; Yang, Li; Cao, Qing-jiu; Wang, Yu-feng

    2007-06-18

    To explore whether methylphenidate (MPH) can improve the executive function (EF) of attention deficit hyperactivity disorder (ADHD) children and the degree of the improvements. We conducted an open study of 29 children (25 boys and 4 girls) who met DSM-IV criteria for ADHD. The variations of their EF before and after methylphenidate extended-release tablets [osmotic release oral system(OROS) methylphenidate] treatment were evaluated, and the differences of EF between 24 ADHD boys before and after treatment and 24 age-matched typically developing control boys were compared. The research instruments included Stroop color-word task, Rey complex figure test, digit span test, trail making test, tower of Hanoi and verbal fluency test. The performances of errors in Stroop 1, time and errors of Stroops 2 and 4; the immediate memory and delay recalling of structure and detail score of RCFT; time of number-letter trail making, shifting time; total time and steps, rule violation of tower of Hanoi improved significantly after OROS methylphenidate treatment as compared with those before treatment. They were no significant differences between ante- and post-treatment. The initiation planning time of tower of Hanoi was significantly shorter after treatment as compared with that before treatment . This study suggests that methylphenidate can improve the executive function in the aspects of inhibition, visual working memory, set shifting and planning in ADHD children, and almost all aspects of EF can reach the normal level except the inhibition.

  14. El austracismo en el reino de Mallorca

    Directory of Open Access Journals (Sweden)

    Josep JUAN VIDAL

    2015-05-01

    Full Text Available Mallorca e Ibiza permanecieron bajo dominio austracista nueve años entre 1706 y 1715. Pero durante todo ese período la posesión del reino no fue pacífica, ya que persistieron sospechas de desafección hacia una serie de conspiradores proborbónicos. El régimen para mantenerse tuvo que adoptar medidas de fuerza, como deportaciones de presos, exilios de filipistas y un control más estricto de los sorteos para proveer los cargos de la Universitat cesando individuos extraídos a suerte para ejercer un cargo por mandato del virrey y dispensando a otros para acceder a ellos. La fidelidad a la causa era preferida a la estricta observancia a la ley. Las noticias recibidas de la península eran enmasacaradas cuando estas se referían a derrotas militares. En Menorca los austracistas quedaron decepcionados. Algunos habían perdido su vida, su cargo y su hacienda por convertirse en súbditos de la Casa de Austria y después quedaron como súbditos de una monarquía no católica.

  15. Penetrógrafo eletrônico automático Automatic electronic recording penetrometer

    Directory of Open Access Journals (Sweden)

    Aloísio Bianchini

    2002-01-01

    Full Text Available O presente trabalho relata o desenvolvimento de um penetrógrafo, construído para operar de forma automática, executando um ensaio de penetração com um simples toque no botão de partida. Ele possui incorporado, um sistema dedicado de aquisição de dados, que pode armazenar até 187 ensaios e uma interface de comunicação, dispensando a conexão ao microcomputador ou "datalogger". As condições do ensaio como, por exemplo, data, localização (latitude e longitude e profundidade, podem ser atualizadas, assim como a aferição da célula de carga, via teclado com mostrador de duas linhas. Verificou-se variação de velocidade This paper presents the development of an automatic recording penetrometer, which operates at the touch of a button. It incorporates a data acquisition system, which can store data of 187 tests and has a serial PC interface. The test characterization such as dates, location (latitude and longitude can be recorded as well. The maximum working depth may be set and the load cell calibration can be verified through a keyboard with 2 lines display. A speed variation error of < 5% compared to ASAE standard was verified for cone indices between 500 and 5,684 kPa. The equipment is compact, easy to handle and can realize one test every minute.

  16. Determinação analítica da performance da irrigação por sulcos abertos e em declive

    Directory of Open Access Journals (Sweden)

    Aristides Fraga Lima Filho

    2015-06-01

    Full Text Available Uma solução analítica foi desenvolvida, para avaliar sulcos abertos e em declive, com base na teoria de Balanço de Volume de Walker e Skogerboe (1987. Essa metodologia é capaz de obter, matematicamente, a performance de um sistema, dispensando a construção de gráficos que definem os parâmetros de avaliação. A solução matemática é baseada no ajuste de equações ao modelo potencial, no cálculo das áreas sob as curvas definidas no ajuste e na intercessão de curvas, obtendo-se, assim, a performance de sistemas de irrigação por sulcos abertos e em declive. Para validação da metodologia, foi realizado um experimento de campo, na Fazenda Experimental da Universidade Federal do Ceará, situada no município de Pentecoste, pertencente ao Centro de Ciências Agrárias. Os dados de campo foram submetidos à análise pelas duas metodologias. Os resultados mostraram que a metodologia analítica pode ser usada para avaliar a irrigação por sulcos abertos e em declive.

  17. [Sinonasal polyposis associated with a deficiency subclass immunoglobulin G: Place of substitution immunoglobulins].

    Science.gov (United States)

    Hoan, Nhung Tran Khai; Karmochkine, M; Laccourreye, O; Bonfils, P

    2014-01-01

    To study the effect of the introduction of a substitution by intravenous Immunoglobulins (Ig IV) at patients with immunoglobulins G (IgG) subclasses deficiency and nasal polyposis. Prospective study concerning five patients with IgG subclasses deficiency and nasal polyposis treated by Ig IV. Rhinologic, otologic and pulmonary symptoms, exacerbations of nasal polyposis, chronic otitis and asthma as well as the number of antibiotics and corticoids treatments were counted during the Ig IV substitution. To study the association between IgIV substitution and the number of exacerbations of nasal polyposis, chronic otitis, asthma and the number of antibiotics and corticoids treatments in patients with IgG subclasses deficiency and nasal polyposis. Five patients with a IgG subclass deficiency and nasal polyposis were substituted. The number of antibiotics and corticoids cures increased at one patient and remained stable at four others. The number of sinus, ear and lung infections as well as the global rhinologic score of symptoms and the endoscopic stage of the nasal polyposis remained stable. In the absence of efficiency of the treatment, this one was interrupted at the end of 6 months for patients n° 1 and n° 3, 24 months for patient n° 4 and 42 months for patient n° 5. The current study failed to highlight clinical improvement in patients wih IgG subclasses deficiency and nasal polyposis treated by Ig IV. A previous study had not allowed to find a link between IgG subclasses deficiency and severity of nasal polyposis, what seems to be confirmed by the absence of improvement brought during the substitution of this deficit in the current study.

  18. Topical corticosteroids or vitamin D analogues for plaque psoriasis?

    Directory of Open Access Journals (Sweden)

    Soledad Venegas-Iribarren

    2017-06-01

    Full Text Available Resumen La psoriasis es una enfermedad inflamatoria crónica frecuente, siendo la variante en placa su forma de presentación más común. Si bien aún no existe una cura, se dispone de medicamentos que inducen remisión y disminuyen las lesiones. Las terapias tópicas, en particular los corticoides y los análogos de vitamina D, se consideran efectivos, pero no está claro cuál de ellos constituiría la mejor alternativa. Para responder esta pregunta utilizamos Epistemonikos, la mayor base de datos de revisiones sistemáticas en salud, la cual es mantenida mediante búsquedas en múltiples fuentes de información, incluyendo MEDLINE, EMBASE, Cochrane, entre otras. Identificamos ocho revisiones sistemáticas que en conjunto incluyen 26 estudios pertinentes a esta pregunta, entre ellos 22 ensayos aleatorizados. Extrajimos los datos desde las revisiones identificadas, reanalizamos los datos de los estudios primarios, realizamos un metanálisis y preparamos tablas de resumen de los resultados utilizando el método GRADE. Concluimos que podría existir poca o nula diferencia en la respuesta clínica entre corticoides tópicos y análogos de vitamina D tópicos. Por otra parte, los corticoides tópicos producen menos irritación en el sitio de aplicación, pero no se encontraron estudios evaluando sus efectos adversos a largo plazo.

  19. Dispositivos inhaladores en la EPOC: ¿Cuál utilizar?

    Directory of Open Access Journals (Sweden)

    2015-06-01

    Full Text Available El tratamiento de la EPOC ha experimentado un avance muy notable en los últimos años debido a la aparición de nuevos broncodilatadores. Actualmente se dispone de broncodilatadores y corticoides inhalados que se pueden administrar una sola vez al día y cada 12 horas, con lo que las combinaciones pueden ser múltiples (Tabla 1. Por tanto, somos capaces de individualizar el tratamiento de los pacientes con EPOC de la misma forma que se hace en otras enfermedades crónicas, como la hipertensión arterial o la diabetes mellitus

  20. Difficulty in managing polypharmacy in the elderly: Case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Rhita Bennis Nechba

    2015-03-01

    Full Text Available Elderly patients with multiple comorbidities are at risk of experiencing adverse drug events. We report a case of skin lesion related to drugs and discuss consequences of polypharmacy in the elderly. An 85-year-old female took the following drugs for a long time: amlodipine, valsartan, hydrochlorothiazide, lysine acetylsalicylate, sinvastatine, and trimetazidine. In June 2013, she presented thoracic pain and received propranolol, tramadol, and paracetamol. One week later, she developed a diffuse skin lesion. In our patient, drugs considered unnecessary were discontinued and corticosteroid was administered orally. Careful monitoring helped improve the outcome. Corticoids were dangerous but necessary to correct the consequence of iatrogeny.

  1. Artrosis de muñeca, estudio y opciones de tratamiento

    OpenAIRE

    Francisco Andrade, G.

    2014-01-01

    La artrosis de muñeca es una patología que se origina generalmente tras una lesión ligamentosa intraósea del carpo, debido a una no unión de fractura de escafoides o después de una fractura articular del radio. Se sabe que la artrosis no mejora ni retrocede, por lo que se debe tener el tratamiento ideal para cada paciente según sus propias necesidades, que van desde el manejo médico (cambios de actividad, inmovilización, AINES o infiltración con corticoides). Cuando falla el tratamiento médic...

  2. Bloqueo nervioso lumbar selectivo guiado por tomografía computada. Nuestra experiencia en un hospital universitario

    OpenAIRE

    A.J. Nielsen; G. Criscuolo; S. González Calvo; N. Larrañaga; J.C. Gallo; S. Kozima

    2013-01-01

    Objetivos: Presentar nuestra experiencia en el tratamiento mínimamente invasivo de la lumbociatalgia con la inyección de corticoides y anestésicos locales bajo control tomográfico. Materiales y métodos: Se realizaron bloqueos selectivos lumbares bajo control tomográfico a 102 pacientes con lumbociatalgia crónica, en un período comprendido entre agosto del 2011 y junio del 2012. Del total de pacientes, se infiltraron 65 a nivel foraminal (64%), 29 a nivel epidural (28%) y 8 a ambos niveles ...

  3. Do antenatal corticosteroids in term elective cesarean sections reduce neonatal respiratory morbidity?

    Directory of Open Access Journals (Sweden)

    Felipe Petour Gazitúa

    2015-10-01

    Full Text Available INTRODUCCIÓN El síndrome de distrés respiratorio neonatal se relaciona con la edad gestacional y vía de parto. Menor edad gestacional y parto vía cesárea se asocian a mayor riesgo. Con lo anterior, surge la necesidad de evaluar estrategias que reduzcan su incidencia. El uso de corticoides antenatales en la inducción de maduración pulmonar en partos prematuros, podría ser beneficioso en fetos de término en que se programe cesárea. OBJETIVO Buscar evidencia bibliográfica que determine si el uso de corticoides antenatales disminuyen la incidencia de síndrome de distrés respiratorio en cesáreas electivas de término. MÉTODOS Se realizó búsqueda de literatura médica en PubMed, LILACS, UpToDate, Trip, SciELO y Cochrane. Se incluyeron estudios terapéuticos aleatorizados y controlados, en humanos, cuya intervención fuera con corticoides en cesáreas electivas de término. RESULTADOS Se seleccionaron dos estudios cuya intervención fueron dos dosis de 12 mg de dexametasona previas a la cesárea. El objetivo primario de ambos estudios fue analizar la incidencia de síndrome de distrés respiratorio y el ingreso a unidad de cuidados intensivos. En ambos hubo menor incidencia de síndrome de distrés respiratorio en el grupo tratado, con resultados estadísticamente significativos. CONCLUSIÓN Se concluye que el uso de corticoides en cesáreas electivas de término disminuye la incidencia de distrés respiratorio e ingreso a unidad de cuidados intensivos. Sin embargo, evidenciamos debilidades que afectan la validez interna de ambos estudios, por lo que es necesario el desarrollo de nuevos estudios que avalen los resultados encontrados para poder cambiar las conductas clínicas en este grupo de estudio.

  4. Topical corticosteroids or vitamin D analogues for plaque psoriasis?

    OpenAIRE

    Soledad Venegas-Iribarren; Romina Andino

    2017-01-01

    Resumen La psoriasis es una enfermedad inflamatoria crónica frecuente, siendo la variante en placa su forma de presentación más común. Si bien aún no existe una cura, se dispone de medicamentos que inducen remisión y disminuyen las lesiones. Las terapias tópicas, en particular los corticoides y los análogos de vitamina D, se consideran efectivos, pero no está claro cuál de ellos constituiría la mejor alternativa. Para responder esta pregunta utilizamos Epistemonikos, la mayor base de datos...

  5. [Unifocal eosinophilic granuloma of the temporal bone].

    Science.gov (United States)

    Rodríguez Fernández-Freire, A; Porras Alonso, E; Benito Navarro, J R; Rodríguez Pérez, M; Hervás Núñez, M J

    2007-01-01

    We present a case of a twelve year old child with a eosinophilic granuloma of the temporal bone. The eosinophilic granuloma is the most frecuent and most benign form of the histiocytosis of the Langerhans cells. The frecuency of the othological manifestations of this condition varies between 15-60 percent and radiologically, the images are characterized by litho-lesions with sharp edges. The diagnosis is histological and the treatment includes surgical intervention accompanied by inter-lesion corticoid-therapy and/or radiotherapy.

  6. Anniversaries: 1997

    Science.gov (United States)

    Schatz, Paul

    1997-01-01

    Centennial Birthdays: 1897 Odd Hassel, Norwegian physical chemist, whose research on the structure of cyclohexane laid the ground work for conformational analysis. He shared the Nobel Prize for Chemistry in 1969 with Sir Derek Barton. Tadeusz Reichstein, Polish-born organic chemist who worked in Switzerland, was one of the first to synthesize vitamin C (ascorbic acid) after it was isolated and identified in 1932. He shared the Nobel Prize for Physiology or Medicine in 1950 with P. S. Hench and E. C. Kendall for his work on corticoid hormones.

  7. Micosis fungoide liquenoide atípica Unusual lichenoid mycosis fungoides

    Directory of Open Access Journals (Sweden)

    F Pulgar

    2011-06-01

    Full Text Available Presentamos un caso de micosis fungoide liquenoide. La paciente presentó prurito intenso, pero con una buena evolución hasta el momento. Tanto clínica como histológicamente se correspondía con un patrón liquenoide, hecho de excepcional frecuencia. Respondió al tratamiento esteroideo tópico de alta potencia.A 53-years-old woman with a lichenoid mycoses fungoides is reported. Both clinical and histological lichenoid pattern was finding, which is unusual. The treatment with high potency corticoids was successfully and the outcome is favorable up to now.

  8. Oesophageal lesions as first manifestation of necrotising sarcoid granulomatosis.

    Science.gov (United States)

    Attou, Rachid; Duttmann, Ruth; Devriendt, Arnaud; De Bels, David

    2015-07-06

    Necrotising sarcoid granulomatosis is a rare disease associating sarcoid-like granulomas, vasculitis and necrosis in the lungs and seldom in extrapulmonary locations. We report the case of a 23-year-old woman with an initial symptom consisting of epigastric pain. Oesophagoscopy demonstrated oesophagitis. Evolution was marked by fever, dyspnoea and pulmonary lesions. The first presumptive diagnosis was Wegener disease but biopsies (of the lungs and the oesophagus) demonstrated the diagnosis of necrotising sarcoid granulomatosis. Evolution was favourable under corticoid therapy. Necrotising sarcoid granulomatosis may present as an extrapulmonary disease and is an important differential diagnosis of other disease such as Wegener disease. 2015 BMJ Publishing Group Ltd.

  9. Terapia médica actual en reumatología

    Directory of Open Access Journals (Sweden)

    N. María Ángela Carreño, Dra.

    2012-07-01

    Full Text Available El tratamiento médico de las enfermedades reumatológicas ha cambiado en forma importante en las últimas décadas. La aparición de los corticoides en 1948, la incorporación del metotrexato en la década del 90 y últimamente la utilización de medicamentos biológicos, han marcado los hitos más importantes en la historia de la especialidad. En este artículo se revisan los fármacos que actualmente se usan de manera regular en la práctica diaria.

  10. Do antenatal corticosteroids in term elective cesarean sections reduce neonatal respiratory morbidity?

    OpenAIRE

    Felipe Petour Gazitúa

    2015-01-01

    INTRODUCCIÓN El síndrome de distrés respiratorio neonatal se relaciona con la edad gestacional y vía de parto. Menor edad gestacional y parto vía cesárea se asocian a mayor riesgo. Con lo anterior, surge la necesidad de evaluar estrategias que reduzcan su incidencia. El uso de corticoides antenatales en la inducción de maduración pulmonar en partos prematuros, podría ser beneficioso en fetos de término en que se programe cesárea. OBJETIVO Buscar evidencia bibliográfica que determin...

  11. Actividad cicatrizante del látex de Jatropha curcas (Angiospermae: Euforbiaceae)

    OpenAIRE

    Salas, Judith; Tello, Verónica; Zavaleta, Alfonso; Villegas, León; Salas, María; Fernández, Irma; Vaisberg, Abraham

    2016-01-01

    Diversas plantas se han utilizado desde la antigüedad por sus propiedades alimenticias y curativas, en el tratamiento de diversas afecciones del hombre y animales, especialmente en las zonas rurales tropicales y subtropicales donde no se cuenta con adecuados niveles de atención sanitaria. En las farmacopeas se menciona una variedad de productos tópicos (cremas, jaleas y ungüentos) que combinan la acción de geles, antisépticos, antibióticos, corticoides y otros agentes antiinflamatorios utiliz...

  12. Chronic unpredictable stress during adolescence causes long-term anxiety.

    Science.gov (United States)

    Chaby, L E; Cavigelli, S A; Hirrlinger, A M; Caruso, M J; Braithwaite, V A

    2015-02-01

    Exposure to stress during adolescence can cause long-term changes in behavior and cognition. Anxiety diagnoses rise during adolescence and are increased by adverse experiences. Currently, it is unknown how long stress during adolescence alters anxiety in adulthood. We found that rats exposed to chronic unpredictable stress during adolescence expressed altered behavior 6.5 months later; showing increased anxiety in a feeding test in a novel environment. Although behavioral changes indicative of anxiety were detected in late adulthood, the basal levels of fecal corticoid metabolites in prior-stressed rats did not differ from unstressed, control rats. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. Topical Calendula officinalis L. successfully treated exfoliative cheilitis: a case report

    Science.gov (United States)

    2009-01-01

    Authors describe a case of recurrent exfoliative cheilitis that responded to treatment with a standardized topical preparation of Calendula officinalis L. An eighteen-year-old man was referred to UNESP - São Paulo State University, Department of Biosciences and Oral Diagnosis, São José dos Campos Dental School to investigate a chronic dry scaling lesion on his lips. The patient's main chief was aesthetic compromising. Corticoid therapy was suspended and Calendula officinalis ointment 10% for ad libitum use has been prescribed. The results presented allow the authors to consider Calendula officinalis L. as a potential therapy in cases of cheilitis exfoliative. PMID:20062714

  14. Presentación de un caso de Pénfigo Vulgar

    OpenAIRE

    Zully Ballesteros Zárate; Julio Cesar Mantilla Hernández; Álvaro Sanabria Naranjo

    2012-01-01

    El pénfigo es una enfermedad vesículo-ampollosa autoinmune de la piel y mucosas, que puede comprometer grandes extensiones; los tipos vulgar y foliáceo son los más frecuentes, con diferencias inmunopatológicas entre ellas. El pénfigo es tratado con corticoides y Azatioprina pero en los últimos años se incluyeron nuevos medicamentos como inmunoglobulinas, Rituximab (anticuerpo monoclonal quimérico anti-CD20) entre otros, Mostramos un caso de pénfigo hiperpigmentado atípico, y revisamos el tema...

  15. Rotura bilateral espontánea del tendón rotuliano asociado a Lupus Eritematoso Sistémico

    OpenAIRE

    Fernández Gabarda, Rafael; Segura Llopis, Francisco; Fernández Fernández, C.I.; Gomar Sancho, Francisco

    1994-01-01

    La rotura bilateral simultánea y espontánea del tendón rotuliano es un hecho poco frecuente, que suele asociarse a enfermedad sistémica y corticoterapia de larga duración. Presentamos el caso de una paciente de 28 años diagnosticada de lupus eritematoso sistémico, recibiendo tratamiento con corticoides durante 10 años. Sufrió de forma espontánea rotura de ambos tendones rotulianos. Se efectuó la reparación quirúrgica de ambos tendones mediante sutura directa apoyada con puntos ...

  16. Diplopia aguda postlaberintectomía química

    OpenAIRE

    Santos Gorjón, Pablo; Collado Lorduy, Teresa; Sánchez Terradillos, Elena; Sánchez-Jara Sánchez, Juan Luis; Velasco García, María Jesús; Martín Hernández, Gonzalo

    2012-01-01

    [ES]Introducción: La laberintectomía química con gentamicina es un procedimiento ambulatorio considerado seguro y eficaz y que provoca poca iatrogenia. Presentamos un caso clínico de una rara complicación de la técnica y se revisa la literatura. Caso clínico: Paciente diagnosticada de enfermedad de Ménière izquierda que no responde a esquema de tratamiento conservador. Se propone realizar terapia intratimpánica con corticoide y después una laberintectomía química. Aparece de forma aguda u...

  17. Are intratympanic corticosteroids effective for Ménière’s disease?

    OpenAIRE

    Ángela Chuang-Chuang; María A Baeza

    2017-01-01

    Resumen La enfermedad de Ménière afecta al oído interno y tiene como principales síntomas el vértigo, la pérdida auditiva y los síntomas aurales fluctuantes. Actualmente existen varias alternativas terapéuticas. El uso de corticoides intratimpánicos es una de las que se ha popularizado, sin embargo, no está clara su real utilidad clínica. Para contestar esta pregunta utilizamos la base de datos Epistemonikos, la cual es mantenida mediante búsquedas en múltiples bases de datos. Identificamo...

  18. Seguimiento multidisciplinario en el control del penfigoide de membranas mucosas Multidisciplinary follow-up in mucous membranes pemphigoid control

    Directory of Open Access Journals (Sweden)

    Fabiano Jeremias

    2011-06-01

    Full Text Available El término penfigoide de membranas mucosas designa un grupo de enfermedades vesículo-bulosas autoinmunes crónicas, que afectan predominantemente mucosas. El presente artículo describe dos casos clínicos de penfigoide de membranas mucosas con compromiso gingival y tuvo como objetivo resaltar la importancia de un correcto diagnóstico de la lesión y discutir la conducta terapéutica. Fueron realizados diversos exámenes complementares como, examen de Nikolsky, biopsia incisional, investigación de células LE y de anticuerpos antinucleares, además de la evaluación de médicos especializados en dermatología y oftalmología. Fue fundamental la substitución de dentífricos, la orientación nutricional y psicológica, el cuidado con la higiene, además del uso de corticoides tópicos. Hubo periodos de remisión y exacerbación del cuadro clínico durante el seguimiento, fue necesario el ajuste en la terapéutica y refuerzo en los cuidados con la higiene bucal. Es muy importante la interacción multidisciplinaria en la atención de estos casos para el control del tratamiento y seguimiento, además de reforzar todas las orientaciones y cuidados en lo que se refiere a la salud bucal y cautela en el uso de corticoides.The term Mucous Membrane Pemphigoid includes a group of chronic and autoimmune vesiculobullous diseases involving mainly the mucosa. The aim of present paper is to describe two clinical cases of Mucous Membrane Pemphigoid with gingival involvement to arrive to a proper diagnosis of the lesion and also to discuss the therapeutic behavior. Different complementary examinations were conducted including Nikolsky test, incisional biopsy, the LE cells study and of antinuclear antibodies, as well as the evaluation of dermatologists and ophthalmologists. It was necessary the replacement of toothpastes, the nutritional and psychological guiding, the hygiene care and the use of topic corticoids. There were periods of remission and

  19. Proteínas de estrés y ejercicio físico

    OpenAIRE

    Inmaculada C Martínez Díaz; Carrasco Páez, Luis; Sañudo Corrales, Francisco de Borja; Hoyo Lora, Moisés del

    2010-01-01

    Uno de mecanismos que posee el organismo para contrarrestar la ruptura de la homeostasis es la producción de proteínas de estrés o heat shock proteins (HSP). Aumentos en la temperatura corporal, en la concentración de Ca2+ y de ciertos corticoides así como disminuciones del pH, de la glucemia y del glucógeno se presentan, junto a la isquemia, como los principales agentes desencadenantes de la respuesta de HSP. La práctica de ejercicio físico integra gran parte de estos facto...

  20. Is rituximab effective for induction of remission in lupus nephritis?

    OpenAIRE

    Macarena Mac-Namara; Gabriel Rada

    2014-01-01

    La combinación de ciclofosfamida y corticoides constituye el tratamiento estándar en pacientes con nefritis lúpica con indicación de terapia inmunosupresora mayor. Sin embargo, se asocia a importantes efectos adversos, por lo que existe interés en otros inmunosupresores como rituximab. Utilizando la base de datos Epistemonikos, la cual es mantenida mediante búsquedas en 19 bases de datos, identificamos 5 revisiones sistemáticas que en conjunto incluyen 24 estudios. Realizamos una síntesis med...

  1. Physiological Adaptations of Arctic Mammals.

    Science.gov (United States)

    1975-01-01

    acclimation in lemmings turned out to be a massive diuresis which at times is represented by an amount of urine equal to the weight of the animal. In the...adaptation to the cold, such as cold diuresis , food consumption, weight loss, urinary pH, 41 Na and K were studied. Cold diuresis was found, stabilizing on...substrates (FFA or glycogen) or the exhaustion of hormones ( corticoids ) and if so, why would that happen sooner in one individual than in another .one? We

  2. ¿Hipoacusia súbita?

    OpenAIRE

    Cornejo Sch,Santiago; García M,Raimundo; San Martín P,José

    2010-01-01

    Se presenta un caso de paciente mujer sin antecedentes mórbidos que consulta a nuestro servicio por síntomas sugerentes de hipoacusia súbita. La evaluación audiométrica y prueba calórica era compatible con una parálisis cocleovestibular y dado que no presentaba contraindicaciones, se decide iniciar tratamiento con corticoides y antiviral oral. La evolución inicial fue favorable sin embargo al control del mes presentó un nuevo deterioro audiométrico. Esto motivó mayor estudio con el cual se pu...

  3. Desorientación y cirrosis. No siempre encefalopatía hepática

    Directory of Open Access Journals (Sweden)

    Sergio Vázquez Rodríguez

    2012-09-01

    Full Text Available Mujer de 49 años de edad, con antecedente de hepatopatía crónica de origen alcohólico e ingreso reciente en nuestro servicio por cuadro clínico compatible con hepatitis alcohólica aguda con criterios de gravedad según índice de Maddrey. Una vez descartada infección concomitante, insuficiencia renal y hemorragia digestiva activa, se inició tratamiento con corticoides a dosis habituales, manteniendo posteriormente dicho tratamiento por mejoría analítica según criterios de Lille.

  4. Tratamiento de epicondilitis refractaria con neurotoxina botulínica tipo A libre de complejo proteínico Treament of refractory epicondilitis with botulin neurotoxin type A free of protein complex

    OpenAIRE

    B. Santos; E. Calderón; P. Ordóñez; R. García-Hernández; L. M. Torres

    2013-01-01

    Introducción: La epicondilitis o "codo de tenista" es un cuadro que se caracteriza por dolor en la inserción proximal del músculo extensor radial corto del carpo. El tratamiento de este cuadro clásicamente se ha basado en fisioterapia e infiltración con corticoides, así como el uso de ortesis. La cirugía se recomienda cuando las estrategias conservadoras no controlan los síntomas después de 6-12 meses de tratamiento. La toxina botulínica es una opción terapéutica cuando fracasan medidas conse...

  5. PRONÓSTICO NEONATAL DEL RECIÉN NACIDO DE MUY BAJO PESO: HOSPITAL REGIONAL DE PUERTO MONTT, 2000-2005

    OpenAIRE

    Caro M,José; Flores H,Gerardo; Ortiz F,Erika; Anwandter Sen,Carlos; Rodríguez A,Daniel

    2007-01-01

    Objetivos: Describir patologías obstétricas asociadas, manejo perinatal y pronóstico neonatal del recién nacido de muy bajo peso al nacer (RNMBPN). Método: Estudio transversal efectuado en el Hospital de Puerto Montt, Chile, en 347 RNMBPN, en el periodo 2000 - 2005. Resultados: La incidencia de RNMBPN fue de 1,59 %. El 70% de las pacientes recibió corticoides prenatales. La principal causa de interrupción fue el síndrome hipertensivo del embarazo. El 68,5% de los partos fueron por cesárea. El...

  6. Evaluación de un modelo experimental de inmunosupresión química en ratones N: NIH-Swiss

    OpenAIRE

    Córdoba, María Alejandra; Del Coco, V.; Sparo, Mónica; Basualdo Farjat, Juan Ángel

    2010-01-01

    La evaluación de infecciones oportunistas de etiología microbiana o parasitaria en animales de laboratorio en calidad de huésped alternativo, exige que éstos se encuentren en condición de inmunosupresión genética o química. Entre los distintos modelos murinos de inmunosupresión química, existen aquellos que utilizan glucocorticoides inoculados oral o intragástricamente. Los corticoides tienen la capacidad de reducir la proliferación y aumentar la apoptosis de células T mediante mecanismos que...

  7. Síndrome Nefrótico y Linfoma de Hodgkin: Reporte de dos casos

    Directory of Open Access Journals (Sweden)

    Luciola Vásquez

    2011-10-01

    Full Text Available Se presentan dos pacientes con síndrome nefrótico sensibles a corticoides y lesiones compatibles con Linfoma de Hodgkin. En uno se encontró una masa mediastinal en la evolución y en el otro un nódulo pulmonar. En ambos casos la biopsia mostró, a la microscopia óptica, hallazgos compatibles con linfoma de Hodgkin Luego de la quimioterapia presentaron remisión de la enfermedad renal.(Rev Med Hered 2011;22:182-185.

  8. Use of oral cholera vaccines in an outbreak in Vietnam: a case control study.

    Directory of Open Access Journals (Sweden)

    Dang Duc Anh

    Full Text Available BACKGROUND: Killed oral cholera vaccines (OCVs are available but not used routinely for cholera control except in Vietnam, which produces its own vaccine. In 2007-2008, unprecedented cholera outbreaks occurred in the capital, Hanoi, prompting immunization in two districts. In an outbreak investigation, we assessed the effectiveness of killed OCV use after a cholera outbreak began. METHODOLOGY/PRINCIPAL FINDINGS: From 16 to 28 January 2008, vaccination campaigns with the Vietnamese killed OCV were held in two districts of Hanoi. No cholera cases were detected from 5 February to 4 March 2008, after which cases were again identified. Beginning 8 April 2008, residents of four districts of Hanoi admitted to one of five hospitals for acute diarrhea with onset after 5 March 2008 were recruited for a matched, hospital-based, case-control outbreak investigation. Cases were matched by hospital, admission date, district, gender, and age to controls admitted for non-diarrheal conditions. Subjects from the two vaccinated districts were evaluated to determine vaccine effectiveness. 54 case-control pairs from the vaccinated districts were included in the analysis. There were 8 (15% and 16 (30% vaccine recipients among cases and controls, respectively. The vaccine was 76% protective against cholera in this setting (95% CI 5% to 94%, P = 0.042 after adjusting for intake of dog meat or raw vegetables and not drinking boiled or bottled water most of the time. CONCLUSIONS/SIGNIFICANCE: This is the first study to explore the effectiveness of the reactive use of killed OCVs during a cholera outbreak. Our findings suggest that killed OCVs may have a role in controlling cholera outbreaks.

  9. Sleep enhances memory consolidation in children.

    Science.gov (United States)

    Ashworth, Anna; Hill, Catherine M; Karmiloff-Smith, Annette; Dimitriou, Dagmara

    2014-06-01

    Sleep is an active state that plays an important role in the consolidation of memory. It has been found to enhance explicit memories in both adults and children. However, in contrast to adults, children do not always show a sleep-related improvement in implicit learning. The majority of research on sleep-dependent memory consolidation focuses on adults; hence, the current study examined sleep-related effects on two tasks in children. Thirty-three typically developing children aged 6-12 years took part in the study. Actigraphy was used to monitor sleep. Sleep-dependent memory consolidation was assessed using a novel non-word learning task and the Tower of Hanoi cognitive puzzle, which involves discovering an underlying rule to aid completion. Children were trained on the two tasks and retested following approximately equal retention intervals of both wake and sleep. After sleep, children showed significant improvements in performance of 14% on the non-word learning task and 25% on the Tower of Hanoi task, but no significant change in score following the wake retention interval. Improved performance on the Tower of Hanoi may have been due to children consolidating explicit aspects of the task, for example rule-learning or memory of previous sequences; thus, we propose that sleep is necessary for consolidation of explicit memory in children. Sleep quality and duration were not related to children's task performance. If such experimental sleep-related learning enhancement is generalizable to everyday life, then it is clear that sleep plays a vital role in children's educational attainment. © 2013 European Sleep Research Society.

  10. Individual differences in control of language interference in late bilinguals are mainly related to general executive abilities

    Directory of Open Access Journals (Sweden)

    Münte Thomas F

    2010-01-01

    Full Text Available Abstract Background Recent research based on comparisons between bilinguals and monolinguals postulates that bilingualism enhances cognitive control functions, because the parallel activation of languages necessitates control of interference. In a novel approach we investigated two groups of bilinguals, distinguished by their susceptibility to cross-language interference, asking whether bilinguals with strong language control abilities ("non-switchers" have an advantage in executive functions (inhibition of irrelevant information, problem solving, planning efficiency, generative fluency and self-monitoring compared to those bilinguals showing weaker language control abilities ("switchers". Methods 29 late bilinguals (21 women were evaluated using various cognitive control neuropsychological tests [e.g., Tower of Hanoi, Ruff Figural Fluency Task, Divided Attention, Go/noGo] tapping executive functions as well as four subtests of the Wechsler Adult Intelligence Scale. The analysis involved t-tests (two independent samples. Non-switchers (n = 16 were distinguished from switchers (n = 13 by their performance observed in a bilingual picture-naming task. Results The non-switcher group demonstrated a better performance on the Tower of Hanoi and Ruff Figural Fluency task, faster reaction time in a Go/noGo and Divided Attention task, and produced significantly fewer errors in the Tower of Hanoi, Go/noGo, and Divided Attention tasks when compared to the switchers. Non-switchers performed significantly better on two verbal subtests of the Wechsler Adult Intelligence Scale (Information and Similarity, but not on the Performance subtests (Picture Completion, Block Design. Conclusions The present results suggest that bilinguals with stronger language control have indeed a cognitive advantage in the administered tests involving executive functions, in particular inhibition, self-monitoring, problem solving, and generative fluency, and in two of the

  11. Individual differences in control of language interference in late bilinguals are mainly related to general executive abilities.

    Science.gov (United States)

    Festman, Julia; Rodriguez-Fornells, Antoni; Münte, Thomas F

    2010-01-13

    Recent research based on comparisons between bilinguals and monolinguals postulates that bilingualism enhances cognitive control functions, because the parallel activation of languages necessitates control of interference. In a novel approach we investigated two groups of bilinguals, distinguished by their susceptibility to cross-language interference, asking whether bilinguals with strong language control abilities ("non-switchers") have an advantage in executive functions (inhibition of irrelevant information, problem solving, planning efficiency, generative fluency and self-monitoring) compared to those bilinguals showing weaker language control abilities ("switchers"). 29 late bilinguals (21 women) were evaluated using various cognitive control neuropsychological tests [e.g., Tower of Hanoi, Ruff Figural Fluency Task, Divided Attention, Go/noGo] tapping executive functions as well as four subtests of the Wechsler Adult Intelligence Scale. The analysis involved t-tests (two independent samples). Non-switchers (n = 16) were distinguished from switchers (n = 13) by their performance observed in a bilingual picture-naming task. The non-switcher group demonstrated a better performance on the Tower of Hanoi and Ruff Figural Fluency task, faster reaction time in a Go/noGo and Divided Attention task, and produced significantly fewer errors in the Tower of Hanoi, Go/noGo, and Divided Attention tasks when compared to the switchers. Non-switchers performed significantly better on two verbal subtests of the Wechsler Adult Intelligence Scale (Information and Similarity), but not on the Performance subtests (Picture Completion, Block Design). The present results suggest that bilinguals with stronger language control have indeed a cognitive advantage in the administered tests involving executive functions, in particular inhibition, self-monitoring, problem solving, and generative fluency, and in two of the intelligence tests. What remains unclear is the direction of the

  12. Proposed Training Plan to Improve Building Energy Efficiency in Vietnam

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Sha; Evans, Meredydd

    2013-01-01

    Vietnam has experienced fast growth in energy consumption in the past decade, with annual growth rate of over 12 percent. This is accompanied by the fast increase in commercial energy use, driven by rapid industrialization, expansion of motorized transport, and increasing energy use in residential and commercial buildings. Meanwhile, Vietnam is experiencing rapid urbanization at a rate of 3.4 percent per year; and the majority of the growth centered in and near major cities such as Hanoi and Ho Chi Minh City. This has resulted in a construction boom in Vietnam.

  13. Effectiveness of oral hygiene after supervised tooth-brushing education in six-year-old children at a primary school in Vietnam

    OpenAIRE

    Lindmark, Ulrika; Do, Thi Thu Hien; Do, Quang Trung; Bengtsson, Ann

    2012-01-01

    Background: The prevalence of dental caries is very high among Vietnamese children why methods and techniques for good oral hygiene behaviours therefore is very important in caries prevention. Aim: To assess oral hygiene before and after supervised tooth-brushing education in six-yearold children. Design: A pilot study with a pre-post-test design was used. Forty children, six years of age, at a primary school in Hanoi, participated in the study. The modified Bass tooth-brushing method were ta...

  14. Optimizing Dispersed Air Operations: A Concept To Use Highways As Improved Airfields In A Contested Environment

    Science.gov (United States)

    2015-04-01

    Afghanistan was people rather than equipment.15 In the Pacific, air strikes during the Vietnam War from Andersen Airbase, Guam, to Hanoi, North...received a message that “many squadrons of B-52 planes have taken off from Andersen Airport.” One half hour later Hanoi’s air defense network went on...mig-29s-and-su-25s-blast-off-from-a-highway-1677293059 29 Katie Hunt, Fighter Jets Land on Highway as Taiwan War Games Begin, CNN, 16 September 2014

  15. Toward Eduscapes

    DEFF Research Database (Denmark)

    Madsen, Ulla Ambrosius

    2008-01-01

    This article presents the output from the cross cutting component on education in the research project entitled Youth and the City: Skills, Knowledge and Social Reproduction. The article presents ethnographic data collected in secondary schools in Recife/Brazil, Lusaka/Zambia and Hanoi/Vietnam an....../Vietnam and discusses methodological challenges in ethnographic and comparative education. Particular focus is on the interaction between education policy reform, classroom practices and young people's negotiation of self and future in a changing world....

  16. Advanced Electronic Systems

    OpenAIRE

    Prêle, Damien

    2016-01-01

    Filters, DC/DC converters, Phase Locked Loop and Modulation; Master; The present document is based on four lectures given for Master of Space and Application in University of Science and Technology of Hanoi. It consists of four parts. The first devoted to filters, the second to DC/DC converter, the third discusses the phase locked loop and the last the modulation. For convenience of the readers the work is organized so that each part is self-contained and can be read independently. These four...

  17. Air pollution episodes associated with East Asian winter monsoons

    Energy Technology Data Exchange (ETDEWEB)

    Hien, P.D., E-mail: pdhien@gmail.com [Vietnam Atomic Energy Agency, 59 Ly Thuong Kiet str. Hanoi (Viet Nam); Loc, P.D.; Dao, N.V. [National Hydro-Meteorological Center, 62-A2 Nguyen Chi Thanh str. Hanoi (Viet Nam)

    2011-11-01

    A dozen multi-day pollution episodes occur from October to February in Hanoi, Vietnam due to prolonged anticyclonic conditions established after the northeast monsoon surges (cold surges). These winter pollution episodes (WPEs) account for most of the 24-h PM{sub 10} exceedances and the highest concentrations of gaseous pollutants in Hanoi. In this study, WPEs were investigated using continuous air quality monitoring data and information on upper-air soundings and air mass trajectories. The 24-h pollutant concentrations are lowest during cold surges; concurrently rise thereafter reaching the highest levels toward the middle of a monsoon cycle, then decline ahead of the next cold surge. Each monsoon cycle usually proceeds through a dry phase and a humid phase as Asiatic continental cold air arrives in Hanoi through inland China then via the East China Sea. WPEs are associated with nighttime radiation temperature inversions (NRTIs) in the dry phase and subsidence temperature inversions (STIs) in the humid phase. In NRTI periods, the rush hour pollution peak is more pronounced in the evening than in the morning and the pollution level is about two times higher at night than in daytime. In STI periods, broad morning and evening traffic peaks are observed and pollution is as high at night as in daytime. The close association between pollution and winter monsoon meteorology found in this study for the winter 2003-04 may serve as a basis for advance warning of WPEs and for forecasting the 24-h pollutant concentrations. - Highlights: {yields} Dozen pollution episodes from Oct. to Feb in Hanoi associated with anticyclones after monsoon surges. {yields} 24-h concentrations of PM{sub 10}, SO{sub 2}, NO{sub 2}, CO rise after surge and decline ahead of the next. {yields} Episodes caused by nighttime radiation and subsidence inversions in dry and humid monsoon phases. {yields} Distinct diurnal variations of pollutant concentrations observed in the two periods. {yields} Close

  18. The fear of awful smell: risk perceptions among farmers in Vietnam using wastewater and human excreta in agriculture

    DEFF Research Database (Denmark)

    Knudsen, Line G; Phuc, Pham D; Hiep, Nguyen T

    2008-01-01

    , but they considered health risks from non-composted smelly feces serious because it entered the body through 'polluted' air. Most farmers were more aware of threats to health from 'dirt' entering the domestic environment than of the health risks during their work. The concept of 'dirt' should be separated from......Vietnamese farmers' health-risk awareness, knowledge, and practices related to their use of wastewater and human excreta was investigated in an anthropological study by a multidisciplinary team in peri-urban Hanoi and Nghe An Province. Farmers identified health risks associated with their use...

  19. A novel strain of porcine deltacoronavirus in Vietnam.

    Science.gov (United States)

    Le, Van Phan; Song, Sok; An, Byung-Hyun; Park, Gyu-Nam; Pham, Ngoc Thach; Le, Dinh Quyen; Nguyen, Van Tam; Vu, Thi Thu Hang; Kim, Ki-Sun; Choe, SeEun; An, Dong-Jun

    2018-01-01

    Two porcine deltacoronavirus (PDCoV) strains (Binh21 and HaNoi6) were isolated from two pig farms in North Vietnam. Phylogenetic analysis of the complete genomes and the Spike and Membrane genes revealed that the two Vietnam PDCoVs belong to the same lineage as PDCoVs from Thailand and Laos; however, the N genes belonged to the same lineage as PDCoVs from the USA, Korea, China, and Hong Kong. The recombination detection program subsequently identified the major parent (S5011 strain) and minor parent (HKU15-44 strain) of the two Vietnam PDCoV strains (p < 0.01).

  20. Bathymetry of the Hong and Luoc River Junction, Red River Delta, Vietnam, 2010

    Science.gov (United States)

    Kinzel, Paul J.; Nelson, Jonathan M.; Toan, Duong Duc; Thanh, Mung Dinh; Shimizu, Yasuyuki

    2012-01-01

    The U.S. Geological Survey, in collaboration with the Water Resources University in Hanoi, Vietnam, conducted a bathymetric survey of the junction of the Hong and Luoc Rivers. The survey was done to characterize the channel morphology of this delta distributary network and provide input for hydrodynamic and sediment transport models. The survey was carried out in December 2010 using a boat-mounted multibeam echo sounder integrated with a global positioning system. A bathymetric map of the Hong and Luoc River junction was produced which was referenced to the datum of the Trieu Duong tide gage on the Luoc River.

  1. Do We Give It to Them, and What Happens If We Do? Issues Concerning Technology Transfers

    Science.gov (United States)

    2008-05-22

    transfers to a government with a poor human rights record. While children are malnourished and ailments afflict the land, the military has great new...2008, and that roughly 35% of India’s population is malnourished .21 Meanwhile, the U.S. significantly increased Foreign Military Sales (FMS) to India...travelling about Vietnam in the 1950’s described a “strong desire for education,” and noted that even the elderly in Hanoi gathered during the day to study

  2. A Study of Strategic Lessons Learned in Vietnam. Omnibus Executive Summary

    Science.gov (United States)

    1980-04-28

    THE CORPORATION Oct r DEN BIEN PHIU * HANOI C0 A Study of Ste ic Lessons Learned EXECUTIVE S MARY BAN METHUOT 0 ; I= T1"-: 1 document hc, been app ov...VIETNAM FORMALLY DIEN BIEN PHI) CONSTITUTIPW wII~~qE RETE SFAF9 PROMULGATED FRANCE TREATY DIEM’SP RECOGNIZES VN ASSUMES SIGNED FRENCH HIOH WINS PARL VIETNAM...NHU AND BEGINS COMUN q IN PARIS 1:(MC.UDF.. DECIDES TO ASSASSINATED REINFORCINGATAIOVR IR SUPPORT WAR NLFIPLAF.ATCKOE OF NAT’L LIBERATION DIRECTS

  3. Perceptions of climate change and its impact on human health: an integrated quantitative and qualitative approach.

    Science.gov (United States)

    Toan, Do Thi Thanh; Kien, Vu Duy; Bao Giang, Kim; Van Minh, Hoang; Wright, Pamela

    2014-01-01

    The World Health Organization emphasized that climate change is a significant and emerging threat to public health, especially in lower income populations and tropical/subtropical countries. However, people in Asia and Africa were the least likely to perceive global warming as a threat. In Vietnam, little research has been conducted concerning the perceptions of effects of climate change on human health. The aim of this study was to explore the perceptions on climate change and its impact on human health among people in Hanoi. We applied a combined quantitative and qualitative approach to study perceptions on climate change among people in Hanoi. A total of 1,444 people were recruited, including 754 people living in non-slum areas and 690 people living in slum areas of Hanoi. A structured questionnaire was used to collect quantitative data on their perceptions. In a parallel qualitative study, two focus group discussions and 12 in-depth interviews (IDs) were carried out involving 24 people from both slum and non-slum areas. The majority of the respondents in the study had heard about climate change and its impact on human health (79.3 and 70.1% in non-slum and slum areas, respectively). About one third of the respondents reported that members of their family had experienced illness in the recent summer and winter compared to the same seasons 5 years ago. The most common symptoms reported during hot weather were headaches, fatigue, and dizziness; hypertension and other cardiovascular diseases were also reported. During cold weather, people reported experiencing cough, fever, and influenza, as well as pneumonia and emerging infectious diseases such as dengue and Japanese encephalitis. The observed high level of awareness on the links between climate change and human health may help to increase the success of the National Prevention Program on Climate Change. Moreover, understanding the concerns of the people may help policy makers to develop and implement effective

  4. Exploring the Concept of Learner Autonomy in Cross-Cultural Research

    Directory of Open Access Journals (Sweden)

    Nga Thanh Nguyen

    2014-09-01

    Full Text Available This research explores how the concept of learner autonomy is understood and used in Vietnamese higher educational settings. Data were collected through interviews in Vietnamese with four university lecturers in Hanoi, Vietnam and then reported in an English language thesis. The problems confronted by the lecturers were in understanding the concept of learner autonomy, the complexities of translation equivalence for the concept from one language to another, and the impact of culture in interpreting the concept of learner autonomy. The paper concludes with recommendations for educators to be sensitive to cultural and linguistic considerations when transferring concepts from one culture to another.

  5. Contents and risks of potentially toxic elements in wastewater-fed food production systems in Southeast Asia

    DEFF Research Database (Denmark)

    Marcussen, Helle

    the concentration range observed for water spinach grown at agricultural soil not exposed to wastewater in Malaysia. Water spinach grown at sites of high and low wastewater exposure did not show a significantly higher accumulation of PTEs compared to sites without wastewater exposure. In Phnom Penh, water spinach...... producing floating aquatic vegetables and from fishing in the lake. Water spinach (Ipomoea aquatica Forssk.) is the most important vegetable produced by weight in the wastewater exposed systems in Hanoi and Phnom Penh. One of the objectives of the study was to determine PTE concentrations in water spinach...

  6. How does traditional Confucian culture influence adolescents' sexual behavior in three Asian cities?

    Science.gov (United States)

    Gao, Ersheng; Zuo, Xiayun; Wang, Li; Lou, Chaohua; Cheng, Yan; Zabin, Laurie S

    2012-03-01

    To investigate whether and how the presence of Confucian cultural norms influences the sexual behaviors of adolescents and young adults in three Asian cities experiencing different levels of economic development. Data for this article were drawn from the international cross-sectional survey on sexual and reproductive health of adolescents and young adults aged 15-24 years in three Asian cities (Hanoi, Shanghai, and Taipei), conducted in 2006. The original sample consisted of a representative group of 17,016 adolescents; while in this study, 16,554 never-married adolescents were included in the analysis. Both face-to-face interview and computer-assisted self-interview approaches were adopted in the survey. Exposure to family concepts, self-cultivation values, gender role concepts, and sexual values were the main measures of traditional Confucian cultural influence. Sexual and intimate behaviors were the main outcome measures, and multi-Cox regression models were used to assess the association between traditional cultural concepts and values and sexual behavior after adjusting for potentially confounding factors. Data were analyzed with SAS software 9.1. The traditional Confucian cultural norms were not weakening evenly, with more entrenchment in Hanoi than in Shanghai and Taipei. Prevalence of sexual coitus among adolescent and young adults was lowest in Hanoi and highest in Taipei, while similar profiles of other intimate behaviors were displayed in the three cities. Associations between respondents' sexual behavior and their cultural concepts and values differed by city. In Hanoi, for all four cultural measures, respondents with more traditional views were less likely to engage in sexual activity. This was also true in Shanghai and Taipei with respect to traditional sexual values and self-cultivation values. However, there was an inverse relationship between sexual behavior and traditional family concepts and gender roles in Shanghai and Taipei; those with more

  7. Childhood disability and parental moral responsibility in northern Vietnam

    DEFF Research Database (Denmark)

    Gammeltoft, Tine

    2008-01-01

    This article explores the roles played by parents living in Hanoi, Vietnam, in shaping the subjectivities of children who are categorized as physically or intellectually impaired. In an effort to comprehend disability in terms of an active and embodied engagement with the world, I employ...... a phenomenologically inspired 'intercorporeal' perspective as a conceptual alternative to 'medical' and 'social' models of disability. Through this approach I show how, in northern Vietnam, disability in children brings into question the moral integrity of their parents and how this compels parents to define...

  8. Developing attitude statements toward illegal immigration: transcultural reliability and utility.

    Science.gov (United States)

    Ommundsen, Reidar; van der Veer, Kees; Le, Hao Van; Krumov, Krum; Larsen, Knud S

    2007-06-01

    This is a report on the utility of a scale measuring attitudes toward illegal immigrants in two samples from nations that have more people moving out of the country than moving into the country. The Attitude toward Illegal Immigrants Scale was administered to 219 undergraduates from Sofia University in Bulgaria, and 179 undergraduates from Hanoi State University in Vietnam. Results yielded a scale with no sex differences, and acceptable alpha coefficients. Item analysis identified the most contributory and least contributory items, with considerable overlap in the two samples. A principal component analysis with varimax rotation was carried out to examine the structure.

  9. Are intraarticular steroids effective for knee osteoarthritis?

    Directory of Open Access Journals (Sweden)

    Jorge Faúndez

    2016-12-01

    Full Text Available Resumen La artrosis de rodilla es una enfermedad crónica, invalidante, de evolución progresiva e irreversible. Los corticoides intraarticulares han sido comúnmente utilizados con el fin de disminuir sus síntomas y retrasar la resolución quirúrgica. Sin embargo, hasta el día de hoy, existe debate sobre su eficacia y seguridad. Utilizando la base de datos Epistemonikos, la cual es mantenida mediante búsquedas en 30 bases de datos, se identificaron 12 revisiones sistemáticas que en conjunto incluyen 41 estudios que contestan la pregunta de interés, entre los cuales se cuentan 40 estudios aleatorizados. Realizamos un metanálisis y tablas de resumen de los resultados utilizando el método GRADE. Concluimos que los corticoides intraarticulares probablemente llevan a una leve disminución del dolor a corto plazo, hacen poca o ninguna diferencia a mediano plazo y podrían no tener ningún efecto a largo plazo.

  10. Progresión a necrólisis epidérmica tóxica por uso de lamotrigina: A propósito de un caso Progression to toxic epidermal necrolysis by using lamotrigina: In connection of a case

    Directory of Open Access Journals (Sweden)

    M X Andreoli

    2008-09-01

    Full Text Available El Síndrome de Stevens Johnson (SSJ, el Síndrome de Superposición (SSJ/ NET y la Necrólisis Epidérmica Tóxica (NET son formas clínicas cutáneo-mucosas graves, desencadenadas por fármacos y muy frecuentemente por anticonvulsivantes. Comunicamos el caso de una paciente medicada por su epilepsia, quién presentó un cuadro incipiente de SSJ empeorando rápidamente hasta derivar en la NET. A pesar de la gravedad, la paciente respondió satisfactoriamente a altas dosis de corticoides sistémicos desde el comienzo y por las medidas de soporte del equipo médico multidisciplinario del hospital.The Stevens Johnson Syndrome, the Overlape Syndrome (SSJ / NET, and the Toxic Epidermal Necrolysis are clinical cutaneous mucouse forms due to drugs administration and most frequently due caused by antiepileptic. We communicate the case of a patient treated with lamotrigina for epilepsy, who presented an incipient case of Stevens Johnson Syndrome, worsened rapidly causing a Toxic Epidermal Necrolysis. Nevertheless, the patient gained a satisfactory answer due to high doses of corticoids, which were given from the beginning as well as the measures and the support of the whole medical team of the hospital.

  11. Is there benefit adding antivirals to corticosteroids for Bell’s palsy in adults?

    Directory of Open Access Journals (Sweden)

    Benjamín Walbaum

    2015-08-01

    Full Text Available La parálisis de Bell es la primera causa de parálisis facial unilateral. El mecanismo etiológico más probable es una inflamación del nervio facial, probablemente por reactivación viral de la familia herpes simplex y varicela zóster. Los corticoides se consideran el pilar del tratamiento, sin embargo no está claro si la adición de antivirales ofrecería un beneficio adicional. Utilizando la base de datos Epistemonikos, la cual es mantenida mediante búsquedas en 30 bases de datos, identificamos 10 revisiones sistemáticas que en conjunto incluyen 16 estudios controlados aleatorizados. Realizamos un metanálisis y tablas de resumen de los resultados utilizando el método GRADE. Concluimos que la adición de antivirales al tratamiento con corticoides probablemente reduce el riesgo de recuperación incompleta en pacientes con parálisis de Bell.

  12. What is the effectiveness of systemic corticosteroids in children with croup?

    Directory of Open Access Journals (Sweden)

    Elizabeth Muñoz-Osores

    2017-06-01

    Full Text Available Resumen Los corticoides sistémicos constituyen un tratamiento habitual en los niños con laringitis aguda obstructiva (croup, sin embargo, no se conoce exactamente cuál es la magnitud de los beneficios y riesgos asociados a su uso. Para responder esta pregunta utilizamos Epistemonikos, la mayor base de datos de revisiones sistemáticas en salud a nivel mundial, la cual es mantenida mediante búsquedas en múltiples fuentes de información, incluyendo MEDLINE, EMBASE, Cochrane, entre otras. Identificamos seis revisiones sistemáticas que en conjunto incluyen 25 estudios aleatorizados pertinentes. Extrajimos los datos desde las revisiones identificadas, reanalizamos los datos de los estudios primarios, realizamos un metanálisis y preparamos tablas de resumen de los resultados utilizando el método GRADE. Concluimos que el uso de corticoides sistémicos aumenta la cantidad de pacientes con mejoría clínica a las 12 horas y disminuye el riesgo de readmisión.

  13. [Castleman disease].

    Science.gov (United States)

    Belletti, Gerardo A; Savio, Verónica; Minoldo, Daniel; Caminos, Susana; Yorio, Marcelo A

    2004-01-01

    A 66 years female, who was since last year under astenia, arthralgias, pimply lesions in spread plates and tests showing eritrosedimentation over 100 mm, anemi, leucocitosis with neutrofilia, policlonal hypergammaglobulinemia, slight proteinuria and IgE on 900. This patient was sporadically treated with corticoids. When made the medical consult had lost 34lb., was under anorexy, as well as dyspepsia. Hemoglobyn 6.9 gr/dl, leucocytes 20000/mm3, neutrofils at 90%, proteinogram the same as former, with hypoalbuminemia. She was taking prednisona, 16 mg/day. When examined showed depress of conscience, astenia, and dermic lesions already quoted. 4 cm nonpainful right axillary adenopaty adhered to deep planes. Medulogram with increased iron, hyperegenerative. Ganglionar biopsia: linfoid hyperplasic process linked to inmune response. Toracoabdominal tomography with adenomegalia in torax and retroperitoneo. Skin biopsia: neutrofilic vasculitis. The patient suspends the 16 mg of prednisona and fever as well as generalized adenopatias come up. After laying aside other ethiologies, and understanding as Castleman Multicentric disease, it is started to supply prednisona 1 mg/kg of weight with a clinical and biochemical fast and outstanding response. After 7 months it was progressively suspended the esteroids and 60 days later, the process fall back; for that, corticoids are restarted, with a good evolution. The illness of Castleman although it is not very frequent, it should be considered as differential diagnosis in those clinical cases that are accompanied with important general commitment, linphadenopaties and respons to steroid therapy.

  14. Do infections with disseminated Mycobacterium avium complex precede sweet's syndrome? A case report and literature review

    Directory of Open Access Journals (Sweden)

    Kenji Hibiya

    2017-01-01

    Full Text Available Sweet's syndrome is reportedly associated with preceding nontuberculous mycobacterial infections (NTMIs. Here, we report on a systemic Mycobacterium intracellulare infection in a patient on corticoid therapy for Sweet's syndrome. Literature searches show that 69.1% of patients with Sweet's syndrome and NTMIs developed this syndrome later than NTMIs and 89.3% of them developed during the clinical course of a rapidly growing mycobacterial infection. The residual cases were associated with slow-growing mycobacteria (14.3%, but only three cases of Mycobacterium avium complex (MAC infections before the onset of Sweet's syndrome have been reported, and all of them were caused by disseminated MAC disease. One of these cases developed during corticoid therapy for Sweet's syndrome, while another case had underlying diabetes mellitus. Hence, the occurrence of systemic MAC disease may be an inevitable consequence of long-term steroid use and underlying diseases. Literature searches also show that cervical lymphadenitis was a predominant symptom in NTMIs (90.5%. The present case did not have cervical lymphadenitis although the previously reported MAC cases did experience it. Therefore, lymphadenitis from NTMIs may be related to the pathogenesis of Sweet's syndrome. Hence, should a patient have systemic infection without lymphadenitis, it will be more difficult to clinically confirm that MAC disease is a predisposing factor for Sweet's syndrome.

  15. Are systemic corticosteroids useful for the management of acute pharyngitis?

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    Gonzalo Alarcón-Andrade

    2018-12-01

    Full Text Available Resumen INTRODUCCIÓN La faringitis aguda constituye un motivo de consulta frecuente, en especial por el dolor asociado a ésta. El manejo habitual incluye antiinflamatorios no esteroidales y antibióticos en casos seleccionados, pero el alivio del dolor no siempre se consigue de manera rápida. Se ha planteado el uso de corticoides como alternativa terapéutica, pero existe controversia al respecto. MÉTODOS Utilizamos Epistemonikos, la mayor base de datos de revisiones sistemáticas en salud, la cual es mantenida mediante búsquedas en múltiples fuentes de información, incluyendo MEDLINE, EMBASE, Cochrane, entre otras. Extrajimos los datos desde las revisiones identificadas, reanalizamos los datos de los estudios primarios, realizamos un metanálisis y preparamos tablas de resumen de los resultados utilizando el método GRADE. RESULTADOS Y CONCLUSIONES Identificamos ocho revisiones sistemáticas que en conjunto incluyen 11 estudios primarios, entre ellos 10 ensayos aleatorizados. Concluimos que el uso de corticoides sistémicos en cursos cortos reduce el dolor asociado a la faringitis aguda, sin aumentar el riesgo de efectos adversos.

  16. Implementation of anaphylaxis management guidelines: a register-based study.

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    Linus Grabenhenrich

    Full Text Available BACKGROUND: Anaphylaxis management guidelines recommend the use of intramuscular adrenaline in severe reactions, complemented by antihistamines and corticoids; secondary prevention includes allergen avoidance and provision of self-applicable first aid drugs. Gaps between recommendations and their implementation have been reported, but only in confined settings. Hence, we analysed nation-wide data on the management of anaphylaxis, evaluating the implementation of guidelines. METHODS: Within the anaphylaxis registry, allergy referral centres across Germany, Austria and Switzerland provided data on severe anaphylaxis cases. Based on patient records, details on reaction circumstances, diagnostic workup and treatment were collected via online questionnaire. Report of anaphylaxis through emergency physicians allowed for validation of registry data. RESULTS: 2114 severe anaphylaxis patients from 58 centres were included. 8% received adrenaline intravenously, 4% intramuscularly; 50% antihistamines, and 51% corticoids. Validation data indicated moderate underreporting of first aid drugs in the Registry. 20% received specific instructions at the time of the reaction; 81% were provided with prophylactic first aid drugs at any time. CONCLUSION: There is a distinct discrepancy between current anaphylaxis management guidelines and their implementation. To improve patient care, a revised approach for medical education and training on the management of severe anaphylaxis is warranted.

  17. Seizures and postictal stupor in a patient with uncontrolled Graves’ hyperthyroidism

    Science.gov (United States)

    De Leu, Nico; Unuane, David; Poppe, Kris; Velkeniers, Brigitte

    2012-01-01

    A 16-year-old girl with a history of Graves’ disease presented with two episodes of generalised tonic-clonic seizures, necessitating intensive care admission. Laboratory examination demonstrated a suppressed thyroid-stimulating hormone level with dramatically elevated free triiodothyronine, free thyroxine and thyroid-stimulating immunoglobulins. Cerebrospinal fluid analysis showed oligoclonal banding in the absence of pleocytosis, thyroid peroxidase antibodies or infection. Neuroimaging revealed the presence of a congenital arachnoid cyst in the right temporal lobe. Despite restoration of euthyroidism and administration of antiepileptic and antiviral drugs, neurological features persisted. Subsequently, intravenous corticoids were administered to exclude the contribution of an underlying autoimmune encephalopathy. The patient gradually recovered and, in retrospect, elevated serum N-methyl-d-aspartic acid-receptor (NMDA-R) antibodies were detected. Although this patient presented with an intracerebral arachnoid cyst that can act epileptogenic per se, the combination of prolonged postictal encephalopathy with unresponsiveness to antiepileptic measures, absence of focal epileptiform activity on EEG, response to corticoids and serum NMDA-R antibody positivity favours the diagnosis of autoimmune NMDA-R encephalitis in this case. PMID:22669927

  18. Seizures and postictal stupor in a patient with uncontrolled Graves' hyperthyroidism.

    Science.gov (United States)

    De Leu, Nico; Unuane, David; Poppe, Kris; Velkeniers, Brigitte

    2012-06-01

    A 16-year-old girl with a history of Graves' disease presented with two episodes of generalised tonic-clonic seizures, necessitating intensive care admission. Laboratory examination demonstrated a suppressed thyroid-stimulating hormone level with dramatically elevated free triiodothyronine, free thyroxine and thyroid-stimulating immunoglobulins. Cerebrospinal fluid analysis showed oligoclonal banding in the absence of pleocytosis, thyroid peroxidase antibodies or infection. Neuroimaging revealed the presence of a congenital arachnoid cyst in the right temporal lobe. Despite restoration of euthyroidism and administration of antiepileptic and antiviral drugs, neurological features persisted. Subsequently, intravenous corticoids were administered to exclude the contribution of an underlying autoimmune encephalopathy. The patient gradually recovered and, in retrospect, elevated serum N-methyl-D-aspartic acid-receptor (NMDA-R) antibodies were detected. Although this patient presented with an intracerebral arachnoid cyst that can act epileptogenic per se, the combination of prolonged postictal encephalopathy with unresponsiveness to antiepileptic measures, absence of focal epileptiform activity on EEG, response to corticoids and serum NMDA-R antibody positivity favours the diagnosis of autoimmune NMDA-R encephalitis in this case.

  19. Síndrome de Melkersson Rosenthal: reporte de un caso y revisión de la literatura Melkersson-Rosenthal syndrome: case report and literature review

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    R. Cosmelli Maturana

    2008-10-01

    Full Text Available El Síndrome de Melkersson Rosenthal se describe como la asociación de edema labial (queilitis granulomatosa de Miescher y/o facial recurrente, parálisis facial recidivante y lengua fisurada. El edema labial recurrente se presenta en uno o ambos labios, el cual puede llegar a ser persistente. Cuando se presenta en forma aislada se considera como una forma monosintomatica de este síndrome. El objetivo de esta revisión es mostrar el seguimiento de un caso clínico atendido en nuestro servicio con el diagnóstico síndrome de Melkersson Rosenthal que presenta una gran queilitis granulomatosa asociada a lengua fisurada, cuyo tratamiento consistió en la infiltración de corticoides intralesionales y una posterior queiloplastía.Melkersson-Rosenthal syndrome is described as the association of recurrent lip edema (Miescher’s cheilitis granulomatosa and/or facial edema, recurrent facial paralysis, and plicated tongue. Recurrent edema occurs in one or both lips, and can be persistent. When lip edema alone occurs, the case is considered a monosymptomatic form of this syndrome. The aim of this review was to discuss the follow-up of a patient seen in our department with the diagnosis of Melkersson-Rosenthal syndrome who presented intense cheilitis granulomatosa associated with plicated tongue. The patient was treated with infiltration of intralesional corticoids and later cheiloplasty.

  20. Testicular adrenal rest tumor in infertile man with congenital adrenal hyperplasia: case report and literature review

    Directory of Open Access Journals (Sweden)

    Giovanni Scala Marchini

    Full Text Available CONTEXT: Synthesis of cortisol and aldosterone is impaired in patients with congenital adrenal hyperplasia (CAH because of 21-hydroxylase deficiency. Men with CAH have low fertility rates compared with the normal population, and this is related to testicular adrenal rest tumors. Findings of azoospermia in combination with a testicular tumor on ultrasound are likely to have a mechanical cause, especially when in the testicular mediastinum. The preferred treatment method consists of intensive corticoid therapy. However, when the tumor is unresponsive to steroid therapy, surgical treatment should be considered. CASE REPORT: We present the case of a male patient with CAH due to 21-hydroxylase deficiency who presented a testicular tumor and azoospermia. Treatment with low daily corticoid doses had previously been started by an endocrinologist, but after 12 months, no significant change in sperm count was found. Although the adrenocorticotrophic hormone and 17-hydroxyprogesterone levels returned to normal values, the follicle-stimulating hormone (FSH, luteinizing hormone and testosterone levels remained unchanged. Ultrasound examination confirmed that the testicles were small and heterogenous bilaterally, and revealed a mosaic area at the projection of the testis network bilaterally. Magnetic resonance imaging confirmed the finding. Testicular biopsy revealed the presence of preserved spermatogenesis and spermiogenesis in 20% of the seminiferous tubules in the right testicle. The patient underwent testis-sparing tumor resection. After 12 months of follow-up, there was no tumor recurrence but the patient still presented azoospermia and joined an intracytoplasmic sperm injection program.

  1. UTILIZACIÓN DE OXITETRACICLINA E HIDROCORTISONA PARA EVITAR ADHERENCIAS EN DISPOSITIVOS INTRAVAGINALES EN OVINOS

    Directory of Open Access Journals (Sweden)

    J. L. SOSA

    2017-06-01

    Full Text Available Los dispositivos intravaginales son utilizados para la inducción y sincronización de celos. Los mismos pueden producir adherencia en las paredes de la vagina. El objetivo del presente trabajo fue probar la efi ciencia de la aplicación de antibióticos y corticoide conjuntamente con los dispositivos para evitar adherencias. La experiencia se realizó con 45 ovejas distribuidas en tres grupos: GC dispositivo sin tratamiento, T1 dispositivo más tetraciclina y T2 dispositivo más tetraciclina y corticoide. Siguiendo el protocolo se procedió al retiro de los mismos a los 12 días. Se realizó un test χ2 para evaluar la efectividad del tratamiento. Las ovejas del T2 no presentaron adherencias. En cambio, se observaron distintos grados de adherencias: en el T1 (53 % y en el GC (46 %. Se puede inferir que la utilización de Tetracicilina más hidrocortisona es efi ciente para evitar la vaginitis y por ende la adherencia de los dispositivos y pérdida por disminución de preñeces posteriores al retiro de los dispositivos.

  2. Osteoporosis grave con aplastamientos vertebrales en dermatomiositis juvenil: Efecto del tratamiento con alendronato oral Severe osteoporosis with vertebral crushes in juvenile dermatomyositis: Effect of oral alendronate therapy

    Directory of Open Access Journals (Sweden)

    Cristina Tau

    2007-02-01

    Full Text Available Los glucocorticoides son usados comúnmente para el tratamiento de enfermedades inflamatorias, autoinmunes, enfermedades malignas, y en la prevención de rechazo de órganos trasplantados. Un efecto secundario frecuente del tratamiento prolongado es la pérdida de masa ósea que se produce por varios mecanismos y es causa de osteoporosis y fracturas vertebrales. El tratamiento con disfosfonatos ha sido propuesto para esta situación. Presentamos un caso clínico de osteoporosis grave en una niña con dermatomiositis juvenil, que respondió favorablemente al tratamiento con disfosfonatos orales.Glucocorticoids are used for the treatment of inflammatory and autoimmune diseases, cancer, and in prevention of organ rejects. A frequent secondary effect of longterm treatment with corticoids is the loss of bone mass, caused by several mechanisms: decrease in the intestinal calcium absorption, increase of the renal calcium excretion at the distal renal tubule, suppressive effect on the osteoblast and also in apoptosis of osteoclasts, inhibition in local production of IGF I (Insulin-like growth factor and IGFBPs (binding IGF I proteins necessary for bone metabolism, and decrease on osteocalcin production. Longterm treatment with corticoids is associated with osteoporosis and vertebral fractures. To improve this condition, treatment with bisphosphonates has been proposed. We present here a clinical case of a girl with dermatomyositis and severe osteoporosis with vertebral crushes, who responded well to oral bisphophonate treatment.

  3. Are steroids effective in toxic epidermal necrolysis and Stevens-Johnson syndrome?

    Directory of Open Access Journals (Sweden)

    Rodrigo Meza

    2017-06-01

    Full Text Available Resumen La necrólisis epidérmica tóxica y el síndrome de Stevens-Johnson son reacciones cutáneas adversas graves a medicamentos e infecciones. Los corticoides se describen como una alternativa terapéutica, sin embargo, su uso es aún controvertido. Utilizando la base de datos Epistemonikos, la cual es mantenida mediante búsquedas en múltiples bases de datos, identificamos cuatro revisiones sistemáticas que en conjunto incluyen once estudios primarios que responden la pregunta de interés. Extrajimos los datos y preparamos una tabla de resumen de los resultados utilizando el método GRADE. Concluimos que no está claro si los corticoides disminuyen la mortalidad o la estadía hospitalaria en la necrólisis epidérmica tóxica y el síndrome de Stevens-Johnson porque la certeza de la evidencia es muy baja.

  4. Zoneamento agroclimático da palma forrageira (Opuntia sp. para o estado da Paraíba

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    Bergson G. Bezerra

    2014-07-01

    Full Text Available A palma forrageira tornou-se, ao longo dos anos, uma importante alternativa forrageira no semiárido brasileiro (SAB principalmente em longos períodos de estiagens. Apesar de sua magnitude para a agropecuária, seu cultivo tem dispensando tratos culturais básicos e embasamento técnico-científico quanto às suas exigências climáticas. Assim, o principal objetivo deste estudo foi elaborar o zoneamento agroclimático da cultura da palma forrageira (Opuntia sp. para o estado da Paraíba. O zoneamento agroclimático da palma forrageira foi elaborado com base nos indicadores climáticos delineados na literatura e nos dados climatológicos de precipitação e temperatura (média, máxima e mínima de 97 localidades do estado da Paraíba. De acordo com os resultados obtidos, a mesorregião da Borborema é a que apresenta as condições climáticas mais favoráveis para o cultivo da palma forrageira. As mesorregiões do Agreste, Sertão e a parte do Litoral, são aptas porém com restrições. No entanto, recomenda-se o cultivo da palma forrageira em todo o território do estado da Paraíba, exceto para a parte costeira da mesorregião do Litoral e região em torno de Areia. Em ambos os casos a inaptidão ocorre em função do excesso de precipitação.

  5. RADIAÇÃO SOLAR ACIMA E ABAIXO DE DOSSEL DE MANGUEZAL NA BARR DO RIBEIRA DO IGUAPE, SP

    Directory of Open Access Journals (Sweden)

    Emerson Galvani, Nádia Gilma Beserra de Lima

    2011-07-01

    Full Text Available Avaliou-se neste trabalho a radiação solar incidente em manguezal na Ilha dos Papagaioslocalizada no rio Ribeira de Iguape no litoral sul do estado de São Paulo. Instalou-se uma torremeteorológica com 10m de altura e junto a esta duas estações meteorológicas sendo uma fixadaa acima do dossel de mangue e outra abaixo do dossel. Utilizou-se dados de radiação solarmonitorado em uma plataforma de coleta de dados (PCD pertencente ao INPE/CPTECinstalada a 10 km do local. O período de medidas compreende entre os dias 1 de janeiro a 31 dedezembro de 2008. Os resultados indicam uma transmissividade do dossel (td média anual de27,3%. Os valores de td oscilaram entre um mínimo nos meses de outono/inverno com 16,5% aum valor máximo na primavera/verão de 44,2%. A curva anual da td apresenta curva inversa àcurva de declinação solar. Os modelos de regressão linear apresentaram elevada correlaçãosendo possível estimar os valores de radiação solar, e suas relações abaixo e acima do dossel, nomanguezal a partir daqueles monitorados em estação meteorológica oficial dispensando emfuturo próximo a manutenção desta estação.

  6. Gestão Ambiental Urbana: o caso da Prefeitura Municipal de Ipiranga-PR

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    Arquimedes Szezerbicki

    2005-06-01

    Full Text Available O presente estudo, dentro da área da Gestão Ambiental da  Engenharia de Produção, está situado na subárea Políticas Ambientais. O objetivo é discutir como o poder público da cidade de Ipiranga–PR vem executando um projeto de Aterro Controlado e como as condições de vida da população urbanas do município são alteradas. Para a consecução do objetivo proposto, além de pesquisa bibliográfica e  documental, foram realizadas observações sistemáticas para a composição do corpus documental da pesquisa. O método empregado foi o indutivo. Verificou-se que o município de Ipiranga adotou um modelo de aterro controlado, reduzindo seu custo operacional. As pesquisas realizadas indicaram que a vida útil projetada dos aterros é de 26,5 anos. Houve uma economia  considerável na construção do sistema, dispensando a construção de sistemas mais complexos. Conclui-se que a idealização do projeto de construção dos aterros controlados do tipo trincheiras de pequenas dimensões, beneficia tanto a população quanto o meio ambiente, visando à economia do município.

  7. Ton That Tung's livers.

    Science.gov (United States)

    Helling, Thomas S; Azoulay, Daniel

    2014-06-01

    Born in the early 20th century, the Vietnamese surgeon Ton That Tung received his medical education in French colonial Indochina at the fledgling l'Ecole de Médecine de Hanoi, the first indigenous medical school in Southeast Asia. The benefactor of a postgraduate position at the medical school, Ton That Tung subsequently obtained his surgical training at the Phù Doãn Hospital in Hanoi and concurrently developed a passion for the study of liver anatomy, pathology, and surgery. His contributions to an understanding of liver anatomy based on meticulous dissection of autopsy specimens antedated and rivaled later work by the famous Western anatomists Couinaud, Healey, Schroy, and others. Ton That Tung's contributions, however, were overshadowed by the intense national struggles of the Vietnamese to establish independent rule and self-governance from the French and by eventual alignment with eastern bloc Communist countries, thus isolating much of his work behind the "Iron Curtain" until well after the end of the Cold War. Nevertheless, Ton That Tung remains a pioneer in liver anatomy and liver surgery. His commitment to surgical science and, more importantly, to the Vietnamese people stands as a tribute to the tireless pursuit of his ideals.

  8. A Matched Case-Control Study of Risk Factors for Breast Cancer Risk in Vietnam

    Directory of Open Access Journals (Sweden)

    J. Nguyen

    2016-01-01

    Full Text Available Background. Vietnam has a low age-standardized incidence of breast cancer, but the incidence is rising rapidly with economic development. We report data from a matched case-control study of risk factors for breast cancer in the largest cancer hospital in Vietnam. Methods. 492 incident breast cancer cases unselected for family history or age at diagnosis and 1306 control women age 25–75 were recruited from the National Cancer Hospital (BVK, Hanoi. Structured interviews were conducted and pathology data was centrally reported at the National Cancer Hospital of Vietnam, in Hanoi. Results. Our analysis included 294 matched pairs. Mean age at diagnosis was 46.7 years. Lower mean parity, older age at first parity, increasing weight and BMI at age 18, and increasing BMI at diagnosis were positively correlated with breast cancer cases compared to controls. Age at first menarche and duration of breastfeeding were not statistically different between cases and controls. Conclusions. In this study we demonstrate that breast cancer in Vietnam is associated with some but not all of the published risk factors from Western populations. Our data is consistent with other studies of breast cancer in Asian populations.

  9. Atmospheric radionuclides from the Fukushima Dai-ichi nuclear reactor accident observed in Vietnam.

    Science.gov (United States)

    Long, N Q; Truong, Y; Hien, P D; Binh, N T; Sieu, L N; Giap, T V; Phan, N T

    2012-09-01

    Radionuclides from the reactor accident at the Fukushima Dai-ichi Nuclear Power Plant were observed in the surface air at stations in Hanoi, Dalat, and Ho Chi Minh City (HCMC) in Vietnam, about 4500 km southwest of Japan, during the period from March 27 to April 22, 2011. The maximum activity concentrations in the air measured at those three sites were 193, 33, and 37 μBq m(-3) for (131)I, (13)(4)Cs, and (13)(7)Cs, respectively. Peaks of radionuclide concentrations in the air corresponded to arrival of the air mass from Fukushima to Vietnam after traveling for 8 d over the Pacific Ocean. Cesium-134 was detected with the (134)Cs/(137)Cs activity ratio of about 0.85 in line with observations made elsewhere. The (131)I/(137)Cs activity ratio was observed to decrease exponentially with time as expected from radioactive decay. The ratio at Dalat, where is 1500 m high, was higher than those at Hanoi and HCMC in low lands, indicating the relative enrichment of the iodine in comparison to cesium at high altitudes. The time-integrated surface air concentrations of the Fukushima-derived radionuclides in the Southeast Asia showed exponential decrease with distance from Fukushima. Copyright © 2011 Elsevier Ltd. All rights reserved.

  10. Hygienic aspects of livestock manure management and biogas systems operated by small-scale pig farmers in Vietnam.

    Science.gov (United States)

    Huong, Luu Quynh; Madsen, Henry; Anh, Le Xuan; Ngoc, Pham Thi; Dalsgaard, Anders

    2014-02-01

    Biogas digesters are widely promoted and increasingly used to treat and generate gas from pig slurry worldwide. The objective of this study was to describe manure management practices with focus on biogas digestion among small scale pig farmers in Hue (50 farmers) and Hanoi (96 farmers) and to assess fecal contamination levels in biogas effluent. Results showed that 84% of the farmers in Hanoi and 42% in Hue used both pig slurry and human excreta for biogas production. Biogas digestion only reduced E. coli concentrations by 1 to 2 log units to 3.70 ± 0.84 Escherichia coli (log10) cfu/ml on average in effluent as compared with raw slurry. Biogas effluent was commonly used to fertilize vegetables or discharged directly into the garden or aquatic recipients. Reduced problems with bad smells and flies were reported as main reasons for establishing a biogas digester. Further studies are needed to assess human and animal health hazards associated with the discharge and use of biogas effluent from small-scale biogas systems. © 2013.

  11. Current Status of Taeniasis and Cysticercosis in Vietnam

    Science.gov (United States)

    Le, Thanh Hoa; Lien, Phan Thi Huong; Eom, Keeseon S.

    2014-01-01

    Several reports on taeniasis and cysticercosis in Vietnam show that they are distributed in over 50 of 63 provinces. In some endemic areas, the prevalence of taeniasis was 0.2-12.0% and that of cysticercosis was 1.0-7.2%. The major symptoms of taeniasis included fidgeted anus, proglottids moving out of the anus, and proglottids in the feces. Clinical manifestations of cysticercosis in humans included subcutaneous nodules, epileptic seizures, severe headach, impaired vision, and memory loss. The species identification of Taenia in Vietnam included Taenia asiatica, Taenia saginata, and Taenia solium based on combined morphology and molecular methods. Only T. solium caused cysticercosis in humans. Praziquantel was chosen for treatment of taeniasis and albendazole for treatment of cysticercosis. The infection rate of cysticercus cellulosae in pigs was 0.04% at Hanoi slaughterhouses, 0.03-0.31% at provincial slaughterhouses in the north, and 0.9% in provincial slaughterhouses in the southern region of Vietnam. The infection rate of cysticercus bovis in cattle was 0.03-2.17% at Hanoi slaughterhouses. Risk factors investigated with regard to transmission of Taenia suggested that consumption of raw meat (eating raw meat 4.5-74.3%), inadequate or absent meat inspection and control, poor sanitation in some endemic areas, and use of untreated human waste as a fertilizer for crops may play important roles in Vietnam, although this remains to be validated. PMID:24850954

  12. International Conference on Finite or Infinite Dimensional Complex Analysis and Applications

    CERN Document Server

    Tutschke, W; Yang, C

    2004-01-01

    There is almost no field in Mathematics which does not use Mathe­ matical Analysis. Computer methods in Applied Mathematics, too, are often based on statements and procedures of Mathematical Analysis. An important part of Mathematical Analysis is Complex Analysis because it has many applications in various branches of Mathematics. Since the field of Complex Analysis and its applications is a focal point in the Vietnamese research programme, the Hanoi University of Technology organized an International Conference on Finite or Infinite Dimensional Complex Analysis and Applications which took place in Hanoi from August 8 - 12, 2001. This conference th was the 9 one in a series of conferences which take place alternately in China, Japan, Korea and Vietnam each year. The first one took place th at Pusan University in Korea in 1993. The preceding 8 conference was th held in Shandong in China in August 2000. The 9 conference of the was the first one which took place above mentioned series of conferences in Vietnam....

  13. Motivation for smoking cessation among drug-using smokers under methadone maintenance treatment in Vietnam.

    Science.gov (United States)

    Tran, Bach Xuan; Nguyen, Long Hoang; Do, Huyen Phuc; Nguyen, Nhung Phuong Thi; Phan, Huong Thu Thi; Dunne, Michael; Latkin, Carl

    2015-10-30

    Smoking cessation treatment service is concerned to be a critical element in methadone maintenance treatment (MMT) in order to diminish the effect of smoke on health outcomes. To implement the smoking cessation services in Vietnam, we examined the stages of change to quit and determined associated factors among MMT patients. We conducted a cross-sectional survey with 1016 MMT patients in five clinics in Hanoi and Nam Dinh province, of those, 932 (91.7%) were ever-smokers. Patients were classified into four groups: "pre-contemplation," "contemplation," "preparation," and "action and maintenance" by using the transtheoretical model. Multivariate logistic regression was applied to determine the associated factor for intention and action to quit smoking. Overall, 96% were not actively trying to quit or maintain abstinence. Age older than 45, HIV-positive status, and residence in Hanoi were negatively associated with intention to quit. Meanwhile, higher levels of nicotine dependence and number of years of smoking negatively associated with quitting and abstinence. The study indicated the high rate of MMT smokers being in pre-contemplation stage but low proportion of quitting and maintaining abstinence. It emphasizes the importance of availability and accessibility of information about smoking cessation therapies and services. Integrating cessation programs into health-care services should be considered to provide tailored interventions for different patient groups.

  14. Antimicrobial susceptibility and genetic characteristics of Neisseria gonorrhoeae isolates from Vietnam, 2011

    Science.gov (United States)

    2013-01-01

    Background Antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a major public health concern worldwide. In Vietnam, knowledge regarding N. gonorrhoeae prevalence and AMR is limited, and data concerning genetic characteristics of N. gonorrhoeae is totally lacking. Herein, we investigated the phenotypic AMR (previous, current and possible future treatment options), genetic resistance determinants for extended-spectrum cephalosporins (ESCs), and genotypic distribution of N. gonorrhoeae isolated in 2011 in Hanoi, Vietnam. Methods N. gonorrhoeae isolates from Hanoi, Vietnam isolated in 2011 (n = 108) were examined using antibiograms (Etest for 10 antimicrobials), Neisseria gonorrhoeae multi-antigen sequence typing (NG-MAST), and sequencing of ESC resistance determinants (penA, mtrR and penB). Results The levels of in vitro resistance were as follows: ciprofloxacin 98%, tetracycline 82%, penicillin G 48%, azithromycin 11%, ceftriaxone 5%, cefixime 1%, and spectinomycin 0%. The MICs of gentamicin (0.023-6 mg/L), ertapenem (0.002-0.125 mg/L) and solithromycin (gonorrhoea treatment (with exception of spectinomycin), but resistance also to the currently recommended ESCs were found. Nevertheless, the MICs of three potential future treatment options were low. It is essential to strengthen the diagnostics, case reporting, and epidemiologic surveillance of gonorrhoea in Vietnam. Furthermore, the surveillance of gonococcal AMR and gonorrhoea treatment failures is imperative to reinforce. Research regarding novel antimicrobial treatment strategies (e.g., combination therapy) and new antimicrobials is crucial for future treatment of gonorrhoea. PMID:23351067

  15. Socio-emotional intervention in attention deficit hyperactive disorder

    Directory of Open Access Journals (Sweden)

    María Jesús Cardoso-Moreno

    2015-06-01

    Full Text Available Attention-deficit-hyperactivity disorder (ADHD is a common neuro-behavioural disorder with onset in childhood. These children have impaired emotional self-control, self-regulation of drive and motivation. Numerous studies have reported cognitive disabilities in memory, executive functions, spatial abilities and language skills. The main objective of this work is to determine whether a socio-emotional intervention programme could improve executive functions in children with Attention Deficit Hyperactivity Disorder. The sample of this study consisted of 25 children (8 female and 17 male aged between 8 and 12 years, diagnosed with ADHD and who were not taking any psychopharmacological treatment at the time of the study, and had not taken medication previously. Executive functioning was assessed through the Zoo Map test and Tower of Hanoi puzzle in pre-/post-test design. A socio-emotional intervention programme was implemented. The training consisted of 8 one-hour weekly sessions, on an individual basis. Results indicate that such a programme does lead to improved performance in the execution of tasks that evaluate executive functions. After the intervention, the children took less time to resolve the Zoo Map test. Results for the Hanoi Tower puzzle were also improved after intervention. The children needed a lower number of movements to complete the task.

  16. Socio-emotional intervention in attention deficit hyperactive disorder

    Directory of Open Access Journals (Sweden)

    María Jesús Cardoso-Moreno

    2015-12-01

    Full Text Available Attention-deficit-hyperactivity disorder (ADHD is a common neuro-behavioural disorder with onset in childhood. These children have impaired emotional self-control, self-regulation of drive and motivation. Numerous studies have reported cognitive disabilities in memory, executive functions, spatial abilities and language skills. The main objective of this work is to determine whether a socio-emotional intervention programme could improve executive functions in children with Attention Deficit Hyperactivity Disorder. The sample of this study consisted of 25 children (8 female and 17 male aged between 8 and 12 years, diagnosed with ADHD and who were not taking any psychopharmacological treatment at the time of the study, and had not taken medication previously. Executive functioning was assessed through the Zoo Map test and Tower of Hanoi puzzle in pre-/post-test design. A socio-emotional intervention programme was implemented. The training consisted of 8 one-hour weekly sessions, on an individual basis. Results indicate that such a programme does lead to improved performance in the execution of tasks that evaluate executive functions. After the intervention, the children took less time to resolve the Zoo Map test. Results for the Hanoi Tower puzzle were also improved after intervention. The children needed a lower number of movements to complete the task.

  17. FY 2000 research cooperation project on the comprehensive research cooperation for environmental technology. Research cooperation for technology for prevention of the water pollution caused by plant waste water in Vietnam; 2000 nendo kenkyu kyoryoku jigyo. Kankyo gijutsu sogo kenkyu kyoryoku (Betonamu koku kojo haisui ni yoru suishitsu osen boshi taisaku gijutsu ni kansuru kenkyu hokoku)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    For the purpose of increasing the research capability of the Center for Consultancy, Training and Technology Transfer in Vietnam, research cooperation for prevention of water pollution was given for plants of the local industry located in the suburbs of Hanoi city. In the survey of the actual state of the water pollution in the industrial area in the suburbs of Hanoi city, the following was found out: In the area, approximately 110 companies of the production industry such as livestock feed, papermaking, dyeing, brewing, construction materials, etc. are in operation and are discharging the untreated waste water into rivers and waterways because waste water treatment facilities are not prepared yet. In this research cooperation, the following were carried out: detailed survey of specified plants and proposal for improvement, training of Vietnamese researchers/engineers in charge of water pollution prevention technology, invitation to/training at Japan of Vietnamese managers/researchers, seminar to be held on the site, equipment to be given that is needed to measure water quality. The equipment to be given is a portable multi-item water quality meter and analytical equipment such as spectrometer, atomic absorption spectrophotometer and gas chromatograph. (NEDO)

  18. Male homosexual identities, relationships, and practices among young men who have sex with men in Vietnam: implications for HIV prevention.

    Science.gov (United States)

    Ngo, Duc Anh; Ross, Michael W; Phan, Ha; Ratliff, Eric A; Trinh, Thang; Sherburne, Lisa

    2009-06-01

    Rapid socioeconomic transformation in Vietnam in last 15 years has been followed by more liberation of sexual expression and representation of sexual identity among young people. There has been an increase in the visibility of homosexual men in major cities of Vietnam who were largely an unknown population until the emergence of the HIV epidemic. Men who have sex with men (MSM) are now considered as one of the target groups in many HIV prevention programs. This qualitative study examines local identities, relationships, and sexual practices among young MSM aged 15-24 in the cities of Hanoi and Ho Chi Minh City. Our analyses were based on 26 in-depth interviews and 10 focus group discussions with young MSM recruited through public place intercepts and cruising areas. Data document the linguistic classification, sexual relationships and behaviors, identity and process of homosexual identification, and the potential linkage between sexual identity and sexual behaviors of MSM in Vietnam. Data also highlight the stages of homosexual community development in urban Vietnam and important differences between Vietnam and the West in the representation of homosexual identity, relationships, and practices. In light of the findings, we suggest that the continuing development and elaboration of a homosexual community in Hanoi and Ho Chi Minh City offers significant opportunities for targeted HIV/AIDS prevention activities in the Vietnamese MSM population.

  19. Seguridad y efectividad de la eliminación linfocitaria en trasplante de manos

    Directory of Open Access Journals (Sweden)

    Luis Landín-Jarillo

    Full Text Available Introducción y Objetivo. Los trasplantes de tejidos compuestos están indicados para casos en los que no hay alternativa reparadora y la reconstrucción alogénica es la única opción terapéutica disponible. Los receptores de tejidos compuestos requieren inmunosupresión crónica que entraña ciertos riesgos. Pese al uso de triple terapia inmunosupresora estándar se pueden producir episodios de rechazo agudo (RA, cuyo tratamiento habitual incluye ajuste del tratamiento, bolos de corticoides y el uso de inmunosupresores de forma tópica, aunque en ocasiones es necesario eliminar la población linfocitaria. En el presente trabajo evaluamos la seguridad y efectividad de la eliminación linfocitaria utilizando globulina anti-timocítica (GAT en el rescate de RA. Material y Método. Llevamos a cabo una revisión sistemática sobre resultados y complicaciones tras la administración de GAT en trasplante de tejidos compuestos, incluyendo un total de 108 publicaciones que resumen la evolución de 57 pacientes. La revisión se acompaña de la presentación del curso inmunológico de 1 paciente trasplantado de brazos en nuestro centro. Resultados. En 5 casos la GAT se administró con éxito para el tratamiento de rechazo resistente a corticoides, si bien no se consiguió prevenir la aparición de episodios de rechazo posteriormente. Nuestro paciente presentó un episodio de RA celular de grado III en la escala Banff que fue tratado con 2 cursos de metil-prednisolona y ajuste al alza del tratamiento inmunosupresor sin respuesta clínica. Finalmente el paciente recibió 2 dosis de GAT en el día 50 y 57 posttrasplante y tras 450 días de seguimiento permanece libre de rechazo. Por el momento no ha presentado complicaciones relacionadas con el uso de GAT. Conclusiones. El rescate del RA resistente a corticoides en trasplantes de tejidos compuestos puede realizarse mediante administración de GAT. Todos los casos descritos en la literatura respondieron

  20. Pathway interactions between MAPKs, mTOR, PKA, and the glucocorticoid receptor in lymphoid cells

    Directory of Open Access Journals (Sweden)

    Thompson E Brad

    2007-03-01

    Full Text Available Abstract Background Glucocorticoids are frequently used as a primary chemotherapeutic agent in many types of human lymphoid malignancies because they induce apoptosis through activation of the glucocorticoid receptor, with subsequent alteration of a complex network of cellular mechanisms. Despite clinical usage for over fifty years, the complete mechanism responsible for glucocorticoid-related apoptosis or resistance remains elusive. The mitogen-activated protein kinase pathway is a signal transduction network that influences a variety of cellular responses through phosphorylation of specific target substrates, including the glucocorticoid receptor. In this study we have evaluated the pharmaceutical scenarios which converge on the mitogen-activated protein kinase pathway to alter glucocorticoid sensitivity in clones of human acute lymphoblastic CEM cells sensitive and refractory to apoptosis in response to the synthetic glucocorticoid dexamethasone. Results The glucocorticoid-resistant clone CEM-C1-15 displays a combination of high constitutive JNK activity and dexamethasone-induced ERK activity with a weak induction of p38 upon glucocorticoid treatment. The cells become sensitive to glucocorticoid-evoked apoptosis after: (1 inhibition of JNK and ERK activity, (2 stimulation of the cAMP/PKA pathway with forskolin, or (3 inhibition of mTOR with rapamycin. Treatments 1–3 in combination with dexamethasone alter the intracellular balance of phospho-MAPKs by lowering JNK phosphorylation and increasing the level of glucocorticoid receptor phosphorylated at serine 211, a modification known to enhance receptor activity. Conclusion Our data support the hypothesis that mitogen-activated protein kinases influence the ability of certain malignant lymphoid cells to undergo apoptosis when treated with glucocorticoid. Activated/phosphorylated JNK and ERK appear to counteract corticoid-dependent apoptosis. Inhibiting these MAPKs restores corticoid sensitivity

  1. Direct long-term effect of hydrocortisone on insulin and glucagon release from mouse pancreatic islets in tissue culture

    DEFF Research Database (Denmark)

    Brunstedt, J; Nielsen, Jens Høiriis

    1981-01-01

    The effects of glucocorticoids on the pancreatic endocrine function was studied in isolated mouse pancreatic islets maintained in tissue culture for 1 to 3 weeks. Following culture for 2 week without corticoid supplement acute experiments with hydrocortisone showed no significant effect...... of hydrocortisone are importance for mouse islets to maintain their insulin production in tissue culture....... on the glucose-induced insulin release at 10(-8) to 10(-5) mol/l hydrocortisone. When, however, the islets were cultured in the presence of hydrocortisone, there was an increased insulin release to the medium in a dose-dependent manner, with the maximal effect at 10(-7) mol/l hydrocortisone. The release...

  2. [Mechanical irrigation and selective decontamination in critically ill patients].

    Science.gov (United States)

    Zejkan, A; Bakosová, M; Drábková, J; Maternová, H; Bejcek, Z; Horejs, J

    1989-09-22

    The authors debugged and launched into routine operation an automated monitoring system using computer techniques. Working off-line, they monitored microbiological, immunologic and biochemical parameters of mechanical irrigation of the mouth and selective decontamination of the gastro-intestinal tract. They ran and classified the data concerned into two index-sequence subsets defined on a set of patients treated with artificial pulmonary ventilation and patients with reduced defenses, and/or corticoid-dependent patients with myasthenia gravis. At present, they study basic sets, representative enough to permit the statistically significant examination of all the parameters under study as well as their exact interpretation with regard to the efficiency of the therapeutical strategy chosen.

  3. Experiencia con rituximab en miopatía inflamatoria idiopática refractaria

    Directory of Open Access Journals (Sweden)

    Elmer R. García-Salazar

    2013-10-01

    Full Text Available Se describe las características clínicas y de laboratorio de dos pacientes que recibieron rituximab por miopatía inflamatoria idiopática (MII. Ellas eran refractarias a tratamiento convencional con DARMES, por lo que recibieron rituximab 1 gramo cada 14 días, en dos infusiones en ciclo semestral. En las historias clínicas se obtuvo los datos clínicos de fuerza muscular proximal, lesiones cutáneas patognomónicas, elevación de CPK, TGO, DHL y VSG, resultados de electromiografía, biopsia muscular y de piel. Ninguno de los dos casos presentó reacción medicamentosa ni infecciones durante y posterior a las infusiones. Rituximab mostró efectividad en la respuesta clínica y enzimática en estas pacientes con dermatomiositis refractarias a corticoides y DARMES tradicionales.

  4. Cardiomyopathie hypertrophique neonatale de diagnostic etiologique difficile

    Directory of Open Access Journals (Sweden)

    Rania Hammami

    2011-12-01

    Full Text Available La cardiomyopathie hypertrophique neonatale est une entite rare, heterogene regroupant plusieurs formes cliniques et donc de diagnostic etiologique difficile. Nous rapportons l�observation d�un nouveau ne issu d�une grossesse gemellaire, ayant presente a la naissance un tableau d�insuffisance cardiaque, l�echocardiographie avait conclut a une cardiomyopathie hypertrophique obstructive. Le bilan etiologique etait negatif notamment une mere non diabetique. L�evolution etait favorable avec regression de l�hypertrophie 2 semaines apres la naissance. L�etiologie finalement suggeree etait une cardiomyopathie secondaire a l�injection antenatale de corticoides dans le but d�accelerer la maturation pulmonaire. L�etablissement par les societes savantes d�un consensus de bilan etiologique minimal standard selon une chronologie bien determinee serait d�un grand apport dans la prise en charge de cette anomalie.

  5. [Ataxia-opsoclonus-myoclonus syndrome].

    Science.gov (United States)

    Pinsard, N; Pons-Cerdan, C; Mancini, J; Livet, M O; Bernard, R

    The ataxia-opsoclonus-myoclonus syndrome that was well individualized by Kinsbourne is mostly observed in young children (less than three years old in 90 percent of the cases). From six personal cases, and from a review of ninety cases of the literature, the clinical and etiological features, as well as the evolution of the syndrome, are studied. Prodromes (infectious and digestive manifestations) and comportmental changes usually precede the sudden onset of the clinical triad. Neurologic complementary investigations are typically normal during the acute phase. The frequent association (46 percent of the cases) of this syndrome to a neuroblastoma (usually thoracic) makes it very particular from the etiological point of view. The evolution is identical whatever the type ("isolated" or "tumoral"). Corticotherapy (ACTH or corticoids) is efficient in 60 percent of the cases. But recurrences and cerebral sequelae (mental deficiency and speech disorders) are frequent.

  6. Discólisis con ozono intradiscal en el tratamiento de la ciática por hernia discal: Seguimiento de 100 pacientes en 24 meses Ozone discolysis in the treatment of sciatica due to a herniated disc: A 24-month follow-up of 100 patients

    OpenAIRE

    L. M. Torres; M.J. Terrero; M; Vidal; F. Aragón; Martínez, J.

    2009-01-01

    Objetivo: Estudio retrospectivo para evaluar la efectividad y la seguridad del uso de ozono para la discólisis en cuadros de ciática por hernia discal contenida. Material y método: Se incluyó en el estudio a 100 pacientes con clínica de lumbociática con dolor intenso, escala visual analógica (EVA) > 6, de más de 3 meses de duración, que no respondieron al tratamiento de analgésicos y corticoides, por vía sistémica, durante un período mínimo de 1 mes, con signos de dolor radicular e irradiació...

  7. Insuficiencia renal crónica y crecimiento

    Directory of Open Access Journals (Sweden)

    T. Pasqualini

    2003-12-01

    Full Text Available El retardo de crecimiento es uno de los mayores problemas de los niños con insuficiencia renal crónica (IRC. En 77% de los varones y 71% de las mujeres con IRC diagnosticada durante la niñez, la altura adulta se halla por debajo del percentilo 3. Los factores que influencian el crecimiento antes del trasplante (Tx son las alteraciones nutricionales, metabólicas y endocrinas; post Tx: la terapia corticoidea inmunosupresora y la alteración de la función del injerto. Sesenta a 64% de los niños llegan al Tx renal con gran deterioro de talla (mediana de talla -2.5 desvíos estándar, DS, no existiendo diferencia entre el DS de talla en el momento del Tx y el DS de talla adulta. Para mejorar el crecimiento post Tx renal, se ha intentado disminuir la dosis de corticoides, administrarlos en días alternos o utilizar corticoides con menos efectos sobre el crecimiento como el deflazacort. Varios estudios demostraron que el tratamiento con hormona de crecimiento (GH es efectivo y esto condujo a que el FDA (Food and Drug Administration lo aprobara como tratamiento de los niños, antes de ser sometidos al Tx renal. La magnitud del aumento de la velocidad de crecimiento es mayor durante el tratamiento conservador, post Tx algo menor, observándose la menor respuesta durante la diálisis. Asimismo, la ganancia de talla se correlaciona con mayor duración del tratamiento con GH durante la etapa prepuberal. Como conclusión, si el deterioro de talla es importante, lo ideal es comenzar el tratamiento a edades tempranas, en la etapa del tratamiento conservador, tratar de acortar el tiempo de diálisis, lograr una talla mejor al momento del Tx, teniendo en cuenta que la talla final está fuertemente relacionada con la talla alcanzada al momento del primer Tx.Many children with chronic renal insufficiency (CRI show growth retardation. Our objective is to describe the natural history of growth in patients with CRI, its pathogenesis and its optimization. Final

  8. [Leading symptom shoulder pain].

    Science.gov (United States)

    Wittke, R

    2003-09-25

    Pain in the shoulder should prompt a systematic clinical examination that adheres closely to the functional anatomy. The basic examination of the shoulder joint comprises active and passive movements and isometric resistance tests with the aid of which external and internal rotation and abduction/adduction can be investigated. The results of these tests provide the physician with a "pattern of findings" which unequivocally identifies the pain-triggering structure. Accordingly, shoulder pain can be classified into four categories as proposed by Cyriax. As treatment, intra-articular injections of corticoids or local anesthetics as determined by findings, where necessary supported by physiotherapeutic measures. Rupture of a tendon, in particular in the case of an active patient, is an indication for surgery.

  9. Corticoterapia profiláctica transquirúrgica de la hiperplasia cicatricial: estudio clínico-estadístico prospectivo

    Directory of Open Access Journals (Sweden)

    César-Kelly Villafuerte-Vélez

    Full Text Available Antecedentes y Objetivo: La hiperplasia cicatricial, denominación que reúne la cicatriz hipertrofica y el queloide, representa un gran desafio en la práctica quirúrgica. Estas patologías que solo acometen a los seres humanos, y en especial el queloide, se han asociado a las razas negra y amarilla, hecho corroborado en el estado de Bahía - Brasil, donde la afro-descendencia es muy significativa y donde gran número de mamoplastias de reducción se acompañan de hiperplasia cicatricial. Son anomalías que generan mucha insatisfacción en los pacientes y en los cirujanos. El objetivo del presente estudio es demostrar que se pueden prevenir este tipo de cicatrices antes de la incisión cutánea y antes del disparo de la cascada de reparación, moldeando las fases iniciales de la cicatrización con el uso de un corticoide especifico. Material y método. Planteamos un estudio prospectivo de prevalencia longitudinal y autocontrolado, en 60 mamas de 30 mujeres con diagnóstico de gigantomastia, a las que se les practicó mamoplastia de reducción en T invertida e injerto de placa areola-papilar (Thorek-Pitanguy, comparando 2 grupos: el primero con 30 mamas derechas infiltradas con solución de corticoide antiquimiotáxico en dermis y subcutáneo, por debajo de la tinta del diseño de la marcación prequirúrgica y antes de las incisiones; y el segundo con 30 mamas izquierdas sin infiltración (grupo control, para determinar estadísticamente, después de un periodo de seguimiento, la eficacia profiláctica del acetato de dexametasona en la prevención de la hiperplasia cicatricial. Tras un seguimiento postoperatorio de 6 a 15 meses, clasificamos el tipo de cicatrización obtenido según la escala de Vancouver, con documentación fotográfica. Realizamos los estudios estadísticos con test de Chi-cuadrado y prueba de Kruskal-Wallis para análisis experimental. Resultados. Comprobamos una disminución estadísticamente significativa al comparar la

  10. Gastrointestinal Biopsy in Henoch-Schönlein Purpura: A Great Diagnostic Contribution

    Directory of Open Access Journals (Sweden)

    Imen Akkari

    2017-09-01

    Full Text Available Henoch-Schönlein purpura is an IgA-mediated immune vasculitis which is characterized by purpuric lesions and osteoarticular, intestinal and sometimes renal manifestations. The histopathological substrate of this entity is leucocytoclastic vasculitis (LCV with IgA deposits seen on immunohistochemistry. We here report the case of a 27-year-old woman with abdominal pain and cutaneous purpura. Upper and lower endoscopic exploration showed purpuric lesions in the rectum but not in the stomach. Skin biopsy revealed LCV. IgA deposits were seen only in gastric mucosa. The patient was treated with corticoids which led to improvement of both the cutaneous and digestive symptoms. This case suggests that gastrointestinal biopsies of both normal and abnormal mucosa should be taken in Henoch-Schönlein purpura, especially in patients with atypical forms.

  11. [Eosinophilic cystitis: review and two case reports].

    Science.gov (United States)

    Ebel Sepulveda, Luis F; Foneron, A; Troncoso, L; Cañoles, R; Carrasco, C; Hornig, A; Gil, G; Corti, D

    2009-04-01

    Eosinophilic cystitis is a low frequency disease, with less than 200 reported cases in the world. It is characterized by a bladder wall inflammation, mainly by eosinophils, with fibrosis and muscle necrosis areas. Its origin seems to be immunological, although the triggers are not well known. Several predispose factor have been described such as allergic diseases, bladder injuries, drugs, infections, etc. It affects patient of all ages, mainly adults. It presents with frecuency, haematuria and suprapubic pain. Other less frequent symptoms are disuria, urinary retention, nicturia, and enuresis. The laboratory study (urinalysis, urinalysis and haemogram) and radiology (ultrasound, intravenous pyelography, computed tomography and nuclear magnetic resonance) are non specific. The lesions observed in the cystoscopy could emulate other diseases, that why the proper diagnostic is the histological analysis. The management could be observation o antihistaminic, anti-inflammatory and corticoid treatment. In refractory cases, surgery is an alternative. In this work, two male adult cases are reported with their symptoms, studies and management.

  12. [Mineralocorticoid syndromes and hypertension].

    Science.gov (United States)

    Waldhäusl, W

    1976-08-26

    Mineralocorticoids are out of the causes of secondary hypertension. Excess production of mineralocorticoids induces sodium and fluid retention, loss of potassium and metabolic alcalosis. The diagnosis of mineralocorticoid syndromes depends on the interpretation of the functional status of the renin-mineralocorticoid-system, which is in part responsible for the maintenance of normal blood pressure. The classical representative of this group is the syndrome of primary aldosteronism. Causes of mineralocorticoid syndromes associated with hypertension are: 1. autonomous production of mineralo-corticoids by an adrenal adenoma or by idiopathic bilateral adrenal hyperplasia; 2. deficiency of adrenal 17-alpha-hydroxylase or of 11-beta-hydroxylase; 3. secondary aldosteronism associated with primary reninism, or renal arterial stenosis; and 4. pseudo aldosteronism due to excessive ingestion of licorice. Malign or essential hypertension may also often be followed by secondary aldosteronism.

  13. [Tracheal resection for post-intubation subglottic stenosis in a patient with granulomatosis with polyangiitis (Wegener)].

    Science.gov (United States)

    Stoica, Radu; Negru, Irina; Matache, Radu; MirunaTodor

    2014-01-01

    Granulomatosis with polyangiitis (GPA or Wegener) is a systemic autoimmune disease with inflammation of small- and medium-size vessels. It can affect practically any organ or system, but renal, respiratory andjoint systems are most frequently damaged. Positive pANCA antibodies can raise the suspicion of diagnosis. Subglottic stenosis is relatively frequent, in a quarter of patients, especially in the third decade women. The case presented is of an 80-year-old woman, recently diagnosed with pulmonary, renal and systemic manifestations of GPA and with a subglottic stenosis rapidly evolving towards endotracheal intubation, tracheostomy with mechanical ventilation and renal failure. Further evolution has been favorable under corticoid therapy. After weaning from the mechanical ventilation and30 days after the suppression of the tracheostomy, the patient developed a tracheal stenosis with mixed etiology, secondary to vasculitis and prolonged intubation with tracheostomy. Tracheal resection with termino-terminal anastomosis was performed in emergency with simple post-operative evolution and without late complications.

  14. New Immunosuppressive Therapies in Uveitis Treatment

    Directory of Open Access Journals (Sweden)

    Salvador Mérida

    2015-08-01

    Full Text Available Uveitis is an inflammatory process that initially starts in the uvea, but can also affect other adjacent eye structures, and is currently the fourth cause of blindness in developed countries. Corticoids are probably the most widespread treatment, but resorting to other immunosuppressive treatments is a frequent practice. Since the implication of different cytokines in uveitis has been well demonstrated, the majority of recent treatments for this disease include inhibitors or antibodies against these. Nevertheless, adequate treatment for each uveitis type entails a difficult therapeutic decision as no clear recommendations are found in the literature, despite the few protocolized clinical assays and many case-control studies done. This review aims to present, in order, the mechanisms and main indications of the most modern immunosuppressive drugs against cytokines.

  15. OSTEOPOROSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS

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    N V Seredavkina

    2009-01-01

    Full Text Available Patients with systemic lupus erythematosus (SLE form a high risk group osteoporosis (OP. Its main causes are autoimmune inflammation, concomitant pathology, and their treatment. When OP occurs in SLE, bone mass loss is shown to occur early and is associated with the use of glucocorticosteroids (GC. To prevent OP, all patients with SLE should modify their lifestyle. To verify bone changes, densitometry is performed in patients who have risk factors of OP and/or a menopause. Calcium preparations and vitamin D are used to prevent OP; bisphosphonates that significantly reduce the risk of fractures of the vertebral column and femoral neck are employed for therapy of OP. A SLE patient with gluco-corticoid-induced OP and a good effect of bisphophonate treatment is described.

  16. Carpal tunnel syndrome - Part II (treatment,

    Directory of Open Access Journals (Sweden)

    Michel Chammas

    2014-10-01

    Full Text Available The treatments for non-deficit forms of carpal tunnel syndrome (CTS are corticoid infiltration and/or a nighttime immobilization brace. Surgical treatment, which includes sectioning the retinaculum of the flexors (retinaculotomy, is indicated in cases of resistance to conservative treatment in deficit forms or, more frequently, in acute forms. In minimally invasive techniques (endoscopy and mini-open, and even though the learning curve is longer, it seems that functional recovery occurs earlier than in the classical surgery, but with identical long-term results. The choice depends on the surgeon, patient, severity, etiology and availability of material. The results are satisfactory in close to 90% of the cases. Recovery of strength requires four to six months after regression of the pain of pillar pain type. This surgery has the reputation of being benign and has a complication rate of 0.2–0.5%.

  17. Artrosis de muñeca, estudio y opciones de tratamiento

    Directory of Open Access Journals (Sweden)

    Dr. G. Francisco Andrade

    2014-09-01

    Full Text Available La artrosis de muñeca es una patología que se origina generalmente tras una lesión ligamentosa intraósea del carpo, debido a una no unión de fractura de escafoides o después de una fractura articular del radio. Se sabe que la artrosis no mejora ni retrocede, por lo que se debe tener el tratamiento ideal para cada paciente según sus propias necesidades, que van desde el manejo médico (cambios de actividad, inmovilización, AINES o infiltración con corticoides. Cuando falla el tratamiento médico, se pueden realizar procedimientos poco invasivos como la denervación, carpectomía proximal o una artrodesis de cuatro esquinas. En estadios avanzados, sólo se puede proponer una artroplastia o artrodesis total de la muñeca.

  18. Aminaphtone in the control of Schamberg's disease

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    de Godoy José

    2009-06-01

    Full Text Available Abstract The aim of this case report is to describe control of Schamberg's disease using aminaphtone. We report on the case of a 28-year-old patient who presented with multiple purpuric lesions of the lower extremities which had appeared spontaneously. A biopsy of the skin was performed that showed a perivascular T-cell lymphocytic infiltrate centered on the small superficial blood vessels of the skin and so a diagnosis of Schamberg's disease was reached. The patient was prescribed corticoids and the lesions disappeared however on suspension of the medication the lesions re-emerged within three to seven days. This treatment was unsuccessfully continued for more than one year. Thus another therapeutic option was attempted: 75 mg of aminaphtone was prescribed twice daily for one month and the purpuric lesions disappeared within about one week. One year after suspending the medication no relapse of the purpura was observed.

  19. 'Femoral head necrosis' in metabolic and hormonal osteopathies

    Energy Technology Data Exchange (ETDEWEB)

    Heuck, F.H.W.; Treugut, H.

    1984-07-01

    The pathogenesis of bone necrosis is discussed with special attention and with respect to metabolic, hormonal, and vascular factors. The influence of statics and dynamics of the hip joint bones for the development of aseptic necrosis are discussed. 45 patients with ''idiopathic femoral head necroses'' were observed, including 6 cases of renal osteopathy following renal transplantation and immune suppression therapy, 14 cases of long term corticoid therapy, and 11 cases of liver diseases of different genesis. The femoral head necrosis understood as complication of an osteopathy. In our patients there were 31 males and 14 females - which means higher involvement of males. Plain radiological findings and CT-findings of changes of the femoral heat structure in different stages of the disease are described. Early diagnosis of metabolic and hormonal osteopathies is demanded for a joint keeping therapy of the beginning femoral head necrosis. 90 refs.

  20. Glomerulopatía membranosa secundaria a infección por Citomegalovirus: Reporte de un caso

    Directory of Open Access Journals (Sweden)

    Reyner Loza-Munarriz

    2012-10-01

    Full Text Available Las causas más frecuentes de síndrome nefrótico en niños son la nefropatía de cambios mínimos y la glomeruloesclerosis focal y segmentaria; las formas secundarias son poco frecuentes. Se presenta el caso de un niño de 5 años y 7 meses de edad, con síndrome nefrótico resistente a corticoides, en quién la biopsia renal mostró nefropatía membranosa con cambios citopáticos focales en las células tubulares, compatibles con citomegalovirus.La inmunofluorescencia mostró depósitos de IgM y C3 en el mesangio. La proteinuria remitió con la terapia con ganciclovir intravenoso, valganciclovir vía oral y ciclofosfamida vía oral.

  1. Sepsis por shigella flexneri

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    César Cabrera C

    2005-04-01

    Full Text Available Se presenta un caso raro de sepsis por Shigella flexneri en una paciente de 45 años de edad quien estando hospitalizada para el estudio de un tumor cerebral, requirió el uso de manitol y dosis altas de corticoides; luego de ello presenta deposiciones líquidas con moco y sangre, desarrolla síndrome de respuesta inflamatoria sistémica, luego se aísla Shigella flexneri en el hemocultivo; recibió tratamiento antibiótico con ciprofloxacina. Se describen las características del caso y se comenta de acuerdo con la revisión de literatura.

  2. Carpal tunnel syndrome – Part II (treatment)☆☆☆

    Science.gov (United States)

    Chammas, Michel; Boretto, Jorge; Burmann, Lauren Marquardt; Ramos, Renato Matta; Neto, Francisco Santos; Silva, Jefferson Braga

    2014-01-01

    The treatments for non-deficit forms of carpal tunnel syndrome (CTS) are corticoid infiltration and/or a nighttime immobilization brace. Surgical treatment, which includes sectioning the retinaculum of the flexors (retinaculotomy), is indicated in cases of resistance to conservative treatment in deficit forms or, more frequently, in acute forms. In minimally invasive techniques (endoscopy and mini-open), and even though the learning curve is longer, it seems that functional recovery occurs earlier than in the classical surgery, but with identical long-term results. The choice depends on the surgeon, patient, severity, etiology and availability of material. The results are satisfactory in close to 90% of the cases. Recovery of strength requires four to six months after regression of the pain of pillar pain type. This surgery has the reputation of being benign and has a complication rate of 0.2–0.5%. PMID:26229842

  3. Micosis fungoide: reporte de un caso clínico

    Directory of Open Access Journals (Sweden)

    Gabriel Abudinén A

    2010-01-01

    Full Text Available La micosis fungoide es una neoplasia maligna originada en los linfocitos T que compromete la piel pudiendo extenderse a médula ósea, linfocitos sanguíneos, ganglios linfáticos y diversos órganos internos. Se presenta el caso de un paciente de 32 años de edad, sexo masculino, que desde hace aproximadamente 1 año presenta lesiones eritematodescamativas pruriginosas inicialmente localizadas en extremidades inferiores y que luego se generalizan, asociándose a baja de peso de aproximadamente 20 Kg. Ha usado corticoides y antihistamínicos, con regular respuesta. Se inicia su estudio por eritrodermia confirmándose por biopsia el diagnóstico de micosis fungoide. Se deriva para iniciar tratamiento específico con Fototerapia con Luz Ultravioleta A (PUVA.

  4. Montmorillonite Clay-Based Polyurethane Nanocomposite As Local Triamcinolone Acetonide Delivery System

    Directory of Open Access Journals (Sweden)

    Flávia Carmo Horta Pinto

    2011-01-01

    Full Text Available Biodegradable polyurethane was synthesized by preparing aqueous polyurethane dispersion having poly(caprolactone and poly(ethylene glycol as soft segments. Montmorillonite particles were delaminated within the waterborne polyurethane to produce a nanocomposite. The triamcinolone acetonide (TA, an important corticoid drug, was dispersed into the nanocomposite followed by a drying step to produce an implantable drug delivery system. Infrared (FTIR results demonstrated that the original chemical structure of the TA was preserved after incorporation into the nanocomposite. Wide angle (WAXS and small angle X-ray scattering (SAXS results suggested that TA and clay do not dramatically change the morphology phase of the polymer although they can interact with each other. The presence of montmorillonite particles in the nanocomposite reduced the rate of TA release as compared to the pure polyurethane and enhanced the mechanical properties of the polymer. The overall results indicate that montmorillonite clay-based polyurethane nanocomposite could be potentially applied as local TA delivery system.

  5. Endurance exercise after orange ingestion anaphylaxis

    Directory of Open Access Journals (Sweden)

    Manu Gupta

    2016-01-01

    Full Text Available Endurance exercise after orange ingestion cause anaphylaxis which is food-dependent exercise-induced anaphylaxis (FDEIA which is a form of exercise-induced anaphylaxis. In this article, an individual develops symptoms such as flushing, itching, urticaria, angioedema, and wheezing after eating a food allergen and proceeds to exercise. Neither the food alone nor exercise alone is sufficient to induce a reaction. This case report describes a 36-year-old asthmatic male athlete who experienced nausea, vomiting, flushing, urticaria, and facial swelling while exercising in a gymnasium after eating oranges. Neither oranges alone nor exercise alone induced the reaction. Total avoidance of suspected food allergens would be ideal. Persons with FDEIA should keep at hand an emergency kit with antihistamines, injectable rapid action corticoids, and adrenaline.

  6. [An unusual cause of acute respiratory distress: obstructive bronchial aspergillosis].

    Science.gov (United States)

    Margery, J; Perez, J-P; Vaylet, F; Bordier, E; Dot, J-M; Saint-Blancard, P; Bonnichon, A; Guigay, J; Pats, B; L'Her, P

    2004-06-01

    We report the case of a 77-Year-old immunocompetent woman who required intensive care for acute dyspnea revealing complete atelectasia of the left lung related to an aspergillus mycelium plug blocking the principal bronchus. The clinical course was favorable after deobstruction by thermocoagulation and oral itraconazole given for six Months. The patient was free of parenchymatous or endobronchial sequelae. Adjuvant oral corticoid therapy was given temporarily during the second Month of treatment when signs of transition towards allergic aspergillosis developed. Four Months after discontinuing the antifungal treatment, the patient developed a new episode of acute dyspnea caused by atelectasia limited to the right lower lobe. Treatment by itraconazole was resumed and continued as long-term therapy. No recurrence has been observed for eighteen Months. The diagnostic and therapeutic problems raised by Aspergillus fumigatus are well known in the immunocompromised subject, but can also be encountered in the immunocompetent subject.

  7. New Immunosuppressive Therapies in Uveitis Treatment

    Science.gov (United States)

    Mérida, Salvador; Palacios, Elena; Navea, Amparo; Bosch-Morell, Francisco

    2015-01-01

    Uveitis is an inflammatory process that initially starts in the uvea, but can also affect other adjacent eye structures, and is currently the fourth cause of blindness in developed countries. Corticoids are probably the most widespread treatment, but resorting to other immunosuppressive treatments is a frequent practice. Since the implication of different cytokines in uveitis has been well demonstrated, the majority of recent treatments for this disease include inhibitors or antibodies against these. Nevertheless, adequate treatment for each uveitis type entails a difficult therapeutic decision as no clear recommendations are found in the literature, despite the few protocolized clinical assays and many case-control studies done. This review aims to present, in order, the mechanisms and main indications of the most modern immunosuppressive drugs against cytokines. PMID:26270662

  8. Does cirrhotic cardiomyopathy exist? 50 years of uncertainty.

    Science.gov (United States)

    Pellicori, Pierpaolo; Torromeo, Concetta; Calicchia, Angela; Ruffa, Alessandra; Di Iorio, Martina; Cleland, John G F; Merli, Manuela

    2013-12-01

    Subtle abnormalities of cardiac structure or function are often identified in patients with liver cirrhosis and have been termed cirrhotic cardiomyopathy. However, in the absence of a precise definition, its diagnosis remains a challenge. Cardiac dysfunction in patients with cirrhosis can often be attributed to concomitant diseases such as hypertension, ischaemic heart disease or excess alcohol consumption in many patients. Further research is required to identify the existence, origin and importance of abnormal cardiac function due specifically to liver disease. Cardiac dysfunction may be masked by treatments given to cirrhotic patients, such as mineral-corticoid receptor antagonists, or by co-existing conditions, such as anaemia. New imaging tests or plasma biomarkers might be able to detect abnormal cardiac function at an early stage of its development.

  9. Esteroides suprarrenales

    Directory of Open Access Journals (Sweden)

    Ricardo Cediel A.

    1957-07-01

    Full Text Available Los corticoides 11-oxigenados aumentan la reabsorción de Na y C1 por los tubos renales y disminuyen las pérdidas de NaCl por el sudor, las glándulas salivares y el tracto digestivo. Además inicialmente producen a veces un aumento del K urinario a lo cual sigue un breve período de retención de K probablemente asocia da con la acumulación de glicógeno en el hígado. Inmediatamente después se observa una continua pérdida de K inducida por la acción anti anabólica de estos esteroides que produce una liberación de N, P Y K del interior de las células.

  10. Trasplante cardíaco en pacientes con enfermedad de Chagas. Experiencia de un único centro

    Directory of Open Access Journals (Sweden)

    Alfredo Inácio Fiorelli

    2011-07-01

    Conclusiones: El trasplante cardíaco es el único tratamiento actual eficaz de tratamiento de la enfermedad de Chagas en fase terminal. La reactivación de la enfermedad es un problema real que es fácilmente revertido con la introducción de la terapéutica farmacológica específica, restaurando los padrones histológicos del miocardio sin dejar secuelas. La inmunosupresión, en especial los corticoides, predisponen al desarrollo de neoplasias y a la reactivación de la enfermedad, exigiendo una atención especial su interrupción o reducción precoz.

  11. [Severe pulmonary involvement in hypocomplementemic urticarial vasculitis (HUV)].

    Science.gov (United States)

    Raoufi, Mohammed; Laine, Mustapha; Amrani, Hicham Naji; Souhi, Hicham; Janah, Hicham; Elouazzani, Hanane; Rhorfi, Ismail Abderrahmane; Abid, Ahmed

    2016-01-01

    Pulmonary involvement in hypocomplementemic urticarial vasculitis (HUV) or Mac Duffie syndrome is extremely rare with a poor prognosis. We report the case of a 55-year-old female patient treated for HUV over a period of 20 years. The diagnosis was confirmed on the basis of urticarial lesions, ocular inflammation, positive C1q-p test by immunodiffusion, with low rate of C1q. The patient was treated with cycles of cyclophosphamide, corticoids and rituximab as she developed class III dyspnea (NYHA classification ). The clinico-radiological and functional assessment showed thoracic distension and severe obstructive pulmonary disease which found no significant improvement with systemic treatment Aerosol therapy was started and the patient had a marked clinical improvement. Pulmonary involvement in Mac Duffie hypocomplementemic urticarial vasculitis worsens the patient short-term vital prognosis. The knowledge of the different types of pulmonary involvement opens new therapeutic prospects.

  12. EPA protects against muscle damage in the mdx mouse model of Duchenne muscular dystrophy by promoting a shift from the M1 to M2 macrophage phenotype.

    Science.gov (United States)

    Carvalho, Samara Camaçari de; Apolinário, Leticia Montanholi; Matheus, Selma Maria Michelin; Santo Neto, Humberto; Marques, Maria Julia

    2013-11-15

    In dystrophic mdx mice and in Duchenne muscular dystrophy, inflammation contributes to myonecrosis. Previously, we demonstrated that eicosapentaenoic acid (EPA) decreased inflammation and necrosis in dystrophic muscle. In the present study, we examined the effects of EPA and the corticoid deflazacort (DFZ) as modulators of M1 (iNOS-expressing cells) and M2 (CD206-expressing cells) macrophages. Mdx mice (14 days old) received EPA or DFZ for 16 days. The diaphragm, biceps brachii and quadriceps muscles were studied. Immunofluorescence, immunoblotting and ELISA assays showed that EPA increased interleucin-10, reduced interferon-γ and was more effective than DFZ in promoting a shift from M1 to M2. © 2013.

  13. [Treatment and results of therapy in autoimmune hemolytic anemia].

    Science.gov (United States)

    Tasić, J; Macukanović, L; Pavlović, M; Koraćević, S; Govedarević, N; Kitić, Lj; Tijanić, I; Bakić, M

    1994-01-01

    Basic principles in the therapy of idiopathic autoimmune hemolytic anemia induced by warm antibody were glucocorticoides and splenectomy. Immunosupresive drugs, plasmaferesis and intravenous high doses gamma globulin therapy are also useful. In secundary autoimmune hemolytic anemia induced by warm antibody we treated basic illness. During the period of 1990-1992 we treated 21 patients with primary autoimmune hemolytic anemia and 6 patients with secondary /4 CLL and 2 Non-Hodgkin's lymphoma/. Complete remission we found as a normalisation of reticulocites and hemoglobin level respectively. Complete remission by corticoides we got in 14/21 patients, partial response in 2/21 respectively. Complete response by splenectomy we got in 2/3 splenoctomized patients (idiopathic type). For successful treatment secondary hemolytic anemias we treated primary diseases (CLL and malignant lymphoma) and we got in 4/6 patients complete remission. Our results were standard in both type of autoimmune hemolytic anaemias induced by warm antibody.

  14. Loxoscelismo en Chile: estudios epidemiológicos, clínicos y experimentales Loxoscelism in Chile: epidemiological, clinical and experimental studies

    Directory of Open Access Journals (Sweden)

    Hugo Schenone

    1989-12-01

    Full Text Available Se presenta un enfoque panorámico de estudios epidemiológicos, clínicos y experimentales referentes a Loxosceles laeta y loxoscelismo efectuados en 1955-1988 en Santiago, Chile. Se estudiaron 216 casos de loxoscelismo. Los hechos más relevantes fueron: 52,8% correspondió a mujeres; edad entre 7 meses y 78 años; 84,3% fué loxoscelismo cutáneo (LO y 15,7% loxoscelismo cutáneo-visceral (LCV; 73,6% sucedió en época calurosa; en 86,6% el accidente ocurrió en la vivienda, especialmente en dormitorios, mientras la persona dormía o se vestía. La araña fué vista en 60,2% de los casos e identificada en laboratorio como L. laeta en 17,7% (10,6% de los 216 casos. Los sitios más frecuen temente afectados fueron las extremidades con 67,6%, lancetazo urente fué el síntoma inicial más frecuente. Dolor, edema y placa livedoide, la cual posteriormente se transformaría en escara necrótica, fueron las manifestaciones locales predominantes. En LCV hematuria y hemoglobinuria fueron constantes, ictericia, fiebre y compromiso de conciencia se presentaron en la mayoría de los casos. Tratamiento: LC con antihistamínicos o corticoides inyectables, LCV con corti-coides inyectables. La condición de los pacientes en el último control fué: curación completa en 75,5%, curación con secuela cicatrizal en 8,3%, muerte en 3,7% (todos con LCV y abandono en 12,5%. Adicionalmente, se ha efectuado una serie de estudios experimentales, tanto in vivo como in vitro para esclarecer aspectos básicos sobre el veneno de L. laeta y el tratamiento del loxoscelismo.A panoramic sight of epidemiological, clinical and experimental studies, referring to Loxosceles laeta and loxoscelism, carried out in 1955-1988, in Santiago, Chile is presented. Two-hundred and sixteen cases of loxosce lism were studied. The most relevant features were: 84.3% corresponded to cutaneous loxosce lism (CD and 15.7% to viscerocutaneous loxos celism (VCD; 73.6% ocurred in hot season; in 86

  15. The value of patch testing patients with a scattered generalized distribution of dermatitis: retrospective cross-sectional analyses of North American Contact Dermatitis Group data, 2001 to 2004.

    Science.gov (United States)

    Zug, Kathryn A; Rietschel, Robert L; Warshaw, Erin M; Belsito, Donald V; Taylor, James S; Maibach, Howard I; Mathias, C G Toby; Fowler, Joseph F; Marks, James G; DeLeo, Vincent A; Pratt, Melanie D; Sasseville, Denis; Storrs, Frances J

    2008-09-01

    A scattered generalized distribution (SGD) of dermatitis is a challenging problem; patch testing is a strategy for evaluating allergic contact dermatitis as a relevant factor. We sought to analyze patient characteristics and most frequently relevant positive allergens in patients presenting for patch testing with SGD. We conducted retrospective cross-sectional analysis of North American Contact Dermatitis Group 2001 to 2004 data. Patients with SGD were compared with patients without SGD. Of 10,061 patients, 14.9% (n = 1497) had only a SGD. Men and patients with a history of atopic eczema were more likely to have dermatitis in a SGD (P cosmetics/beauty preparations/skin and health care products, clothing, and topical corticoids. This was a retrospective analysis of patch-tested patients with SGD suspected to have allergy. A total of 49% of patients with SGD had at least one relevant positive allergen, thus demonstrating the benefit of patch testing these patients.

  16. Factores de riesgo asociados a osteopenia del prematuro en una terapia intensiva neonatal de referencia

    Directory of Open Access Journals (Sweden)

    MP Ríos-Moreno

    2016-03-01

    Full Text Available INTRODUCCIÓN: la enfermedad ósea metabólica del prematuro resulta de la desmineralización ósea. Existen factores que deben vigilarse con la finalidad de realizar diagnóstico y tratamiento temprano. OBJETIVO: determinar los factores de riesgo asociados a osteopenia en prematuros. MATERIALES Y MÉTODOS: estudio transversal comparativo de octubre del 2011 a octubre del 2013. Se incluyeron 120 prematuros 900 UI/L. Factores de riesgo determinados con razón de momios (OR. Estadística inferencial con c2 y t de Student. RESULTADOS: se diagnosticó enfermedad ósea metabólica en 58 prematuros (48%, peso 1067 ± 216 gramos, edad gestacional 28 ± 1.6 semanas, edad postnatal 41 ± 15.5 días. Género masculino 32 (55%. Factores de riesgo: peso < 1,000 gramos OR 4.64, (2.13-10.10, displasia broncopulmonar moderada o severa OR 3.13 (1.44-6.81, tres o más eventos de sepsis OR 3.43 (1.62 7.28, sedación prolongada OR 4.09 (1.06-15.73 y corticoide prolongado OR 9.54 (2.06-44.16.  CONCLUSIONES: nuestros resultados muestran que los factores de riesgo para enfermedad ósea metabólica del prematuro fueron peso al nacer menor de 1,000 gramos, displasia broncopulmonar moderada o severa, tres o más eventos de sepsis, sedación y corticoides durante tiempo prolongado.

  17. Mortalidad en recién nacidos de extremo bajo peso al nacer en la unidad de neonatología del Hospital Nacional Cayetano Heredia entre enero 2000 y diciembre 2004.: January 2000 to December 2004

    Directory of Open Access Journals (Sweden)

    Pablo Lohmann Gandini-Billinghurst

    2006-07-01

    Full Text Available Objetivos: Identificar los factores demográficos y clínicos más frecuentes en recién nacidos con peso menor a 1 000g al nacimiento (extremo bajo peso fallecidos en la unidad de neonatología del Hospital Nacional Cayetano Heredia. Material y métodos: El estudio diseñado es una serie de casos. Se evaluaron las epicrisis y la base de datos NEOCOSUR de los pacientes con estas características, fallecidos durante la hospitalización, de enero 2000 a diciembre 2004. Resultados: Se encontraron 99 pacientes, con registros completos en 87 de ellos (88% de la muestra. La mortalidad en esta población fluctuó entre 70 y 85%, siendo las siguientes condiciones clínicas más frecuentes: control prenatal inadecuado, edad gestacional menor a 27 semanas, uso de corticoides prenatales, empleo de surfactante, enfermedad de membrana hialina-síndrome de distrés respiratorio y hemorragia intraventricular. Conclusiones: Los cuidados prenatales, el uso de corticoides prenatales y surfactante son factores modificables que tendrían impacto en la mortalidad. Síndrome de Distrés Respiratorio-membrana hialina, sepsis y hemorragia intraventricular, constituyen las entidades de morbilidad más frecuentes. El alcance de este estudio permite formular estas hipótesis. La evaluación de las mismas requiere estudios tipo observacionales y analíticos posteriores. (Rev Med Hered 2006;17:141-147.

  18. Guide to Treatment of Tattoo Complications and Tattoo Removal.

    Science.gov (United States)

    Serup, Jørgen; Bäumler, Wolfgang

    2017-01-01

    Clinicians in the fields of general medicine, dermatology, and plastic surgery are in their work now and then confronted with tattoo complications. Recognizing the rather few important diagnostic groups and urgencies, the medical 'decision tree' of treatment becomes quite simple. Acute conditions are dominated by bacterial infections needing antibiotic treatment. Systemic infection is a matter of urgency and requires intravenous treatment in a hospital without delay to prevent septic shock. Inflammatory reactions are a real challenge. Chronic allergic reactions in red tattoos are mostly nonresponsive to topical corticoid and best treated with dermatome shaving with complete removal of the hapten concentrated in the outer dermis. Laser treatment of allergic reactions can boost the allergy with worsening and a potential risk of anaphylaxis and is thus not recommended in tattoo allergy. Chronic papulonodular reactions in black tattoos with pigment agglomeration can respond to local corticoid or be treated with dermatome shaving or lasers depending on availability. It is important to recognize sarcoidosis, which is strongly associated with reactions in black tattoos. Tattoo complications also include many rare but specific entities, which require individual treatment depending on the case and the disease mechanism. Removal of tattoos in individuals regretting their tattoo is performed using Q-switched nanosecond lasers and the recently introduced picosecond lasers. In view of the various tattoo pigments with different absorption spectra and the limited number of laser wavelengths, it is difficult to predict treatment outcome, and it is recommended to pretreat small test spots. Black and red colors are removed best, while other colors are difficult. Removal of large tattoos, especially when multicolored, is hardly achievable and not recommended. Clients often have unrealistic expectations, and informed consent and dialogue between the client and the laser surgeon before

  19. Antenatal corticosteroid treatment for the prevention of peri-intraventricular haemorrhage in preterm newborns: a retrospective cohort study using transfontanelle ultrasonography

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    Bianca A. Almeida

    2017-06-01

    Full Text Available Objective: The objective of this study was to assess the correlation between antenatal corticosteroids and peri-intraventricular haemorrhage (PIVH using transfontanelle ultrasonography, as well as to evaluate the risk factors for its incidence. Methods: We performed a retrospective cohort study using medical records of preterm newborns. The protocol for maternal corticoid administration for foetal lung maturation included dexamethasone 4 mg (intramuscular 8/8 hours per 48 hours, with one cycle per week. The diagnosis of periintraventricular haemorrhage was based on transfontanelle ultrasonography, using the Papile’s classification. The following risk factors for peri-intraventricular haemorrhage were assessed: birth weight, gestational age at delivery, type of delivery, newborn’s sex, surfactant administration, premature rupture of membranes and previous history of infection during the current pregnancy. The student’s t-test and chi-square test were used for statistical analysis. Results: Our sample population included 184 preterm newborns. Transfontanelle ultrasonography revealed peri-intraventricular haemorrhage in 32 (74.4% and periventricular leukomalacia in 11 (25.6% newborns. Grade I haemorrhage was found in 20 (62.5%, grade II in five (15.6%, and grade III in seven (21.8% newborns, as in accordance with Papile’s classification. Vaginal delivery (p = 0.010, birth weight <1500 g (p = 0.024, gestational age at delivery ≤32 weeks (p = 0.018, and previous history of infection during pregnancy (p = 0.013 were considered risk factors for peri-intraventricular haemorrhage in preterm newborns. Conclusion: Maternal corticoid administration for foetal lung maturation showed a protective effect against peri-intraventricular haemorrhage in preterm newborns. The risk factors for peri-intraventricular haemorrhage were determined.

  20. Seguimiento multidisciplinario en el control del penfigoide de membranas mucosas

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    Fabiano Jeremias

    2011-06-01

    Full Text Available El término penfigoide de membranas mucosas designa un grupo de enfermedades vesículo-bulosas autoinmunes crónicas, que afectan predominantemente mucosas. El presente artículo describe dos casos clínicos de penfigoide de membranas mucosas con compromiso gingival y tuvo como objetivo resaltar la importancia de un correcto diagnóstico de la lesión y discutir la conducta terapéutica. Fueron realizados diversos exámenes complementares como, examen de Nikolsky, biopsia incisional, investigación de células LE y de anticuerpos antinucleares, además de la evaluación de médicos especializados en dermatología y oftalmología. Fue fundamental la substitución de dentífricos, la orientación nutricional y psicológica, el cuidado con la higiene, además del uso de corticoides tópicos. Hubo periodos de remisión y exacerbación del cuadro clínico durante el seguimiento, fue necesario el ajuste en la terapéutica y refuerzo en los cuidados con la higiene bucal. Es muy importante la interacción multidisciplinaria en la atención de estos casos para el control del tratamiento y seguimiento, además de reforzar todas las orientaciones y cuidados en lo que se refiere a la salud bucal y cautela en el uso de corticoides.

  1. Bases biológicas do transtorno de estresse pós-traumático Biological basis of posttraumatic stress disorder

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    Frederico G Graeff

    2003-06-01

    Full Text Available A pesquisa neuroendocrinológica dos sistemas fisiológicos envolvidos no estresse evidencia hiper função do eixo simpato-adrenal em conjunto com uma redução da atividade do eixo hipotálamo-hipófise-adrenal (HHA em pacientes com estresse pós-traumático (TEPT. Uma resposta prejudicada do cortisol aos estressores parece estar associada com um aumento da vulnerabilidade ao desenvolvimento do TEPT. O excesso de catecolaminas, sem o pareamento do aumento dos corticóides promoveria uma consolidação excessiva das memórias traumáticas e a indevida generalização para outras situações estressantes. Sintomas como o entorpecimento e flashbacks têm sido relacionados com o aumento de opióides endógenos. Estudos de neuroimagem evidenciam uma redução do volume hipocampal no TEPT, que tem sido relacionada a alterações cognitivas e anormalidades do eixo HHA encontrados no TEPT.Neuroendocrinological research on the physiological systems involved in stress evidenced hyper functioning of the sympatho-adrenal axis together with reduced activity of the hypothalamic-pituitary-adrenal axis in patients with posttraumatic stress disorder (PTSD. An impaired corticoid response to stressors seems to be associated with enhanced vulnerability to PTSD. Excess catecholamines, unchecked by corticoids would promote over consolidation of traumatic memories and undue generalization to other stressful situations. Symptoms such as numbing and flashbacks have been related to endogenous opioids. Neuroimaging studies evidenced a reduction of hippocampal volume in PTSD patients, which has been related to both cognitive changes and abnormalities of the HPA axis that are found in PTSD.

  2. Alveolitis: Revisión de la literatura y actualización

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    Odalys Martín Reyes

    2001-12-01

    Full Text Available La alveolitis es la complicación más frecuente de la extracción dentaria. Su frecuencia varía del 1 al 4 % y puede llegar del 20 al 30 % en extracciones de terceros molares mandibulares. Se describen algunos factores de riesgo que aumentan su incidencia, aunque se habla de un origen multifactorial. La clínica y los síntomas subjetivos nos permiten su diagnóstico y clasificación. Para tratar las alveolitis se han utilizado localmente distintos productos para inducir la formación del coágulo: antibióticos, anestésicos, analgésicos y antiinflamatorios, asociados o no con corticoides, analgésicos y antibióticos sistémicos. También la medicina natural y tradicional ocupa un lugar importante en el tratamiento de esta urgencia estomatológica, y se destacan terapéuticas como: la apiterapia, la acupuntura y la ozonoterapia, además tecnologías de avanzada como los soft láser.Alveolitis is the most frequent complication of tooth extraction. Its frequency varies from 1 to 4 % and may reach 20 to 30 % in extractions of mandibular third molars. Some risk factors increasing its incidence are described, although reference is made to a multifactorial origin. The clinic and the subjective symptoms allow us to make its diagnosis and to classify it. Different products have been used in the treatment of alveolitis to induce clot formation: antibiotics, anesthesics, analgesics and anti-inflammatories associated or not with corticoids, analgesics and systemic antibiotics. Natural and traditional medicine also play an important role in the treatment of this stomatological emergency and therepeutics such as the apiotherapy, the acupuncture, the ozone therapy and state-of-the art technologies as the soft laser are stressed.

  3. Oral Gavage in Rats: Animal Welfare Evaluation

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    Turner, Patricia V; Vaughn, Elizabeth; Sunohara-Neilson, Janet; Ovari, Jelena; Leri, Francesco

    2012-01-01

    The effect of chronic daily orogastric gavage with water (5 mL/kg) on behavior and physiology was evaluated in male Sprague–Dawley rats. Treatment groups included: unmanipulated control, restraint control, dry gavage, and gavage, with all rats singly housed (n = 9 or 10 per group). In addition, a group of pair-housed rats (n = 18) was included to determine whether social housing affected response to gavage. Weekly body weights and food consumption were recorded as well as use of a nylon chew toy for enrichment. Feces were collected biweekly at the end of the light and dark phases for fecal corticoid metabolite determinations. After 28 d of treatment, animals underwent conditioned place preference testing to evaluate sensitivity to motivational properties of the anxiolytic drug chlordiazepoxide (5.6 mg/kg SC). Brain and paired adrenal gland weights were collected at necropsy. Week 2 total fecal corticosterone levels were elevated in all groups and attributed to a fire alarm accidentally tripped during building renovations. No differences occurred in body weight or food consumption between any groups. All groups used a nylon chew toy given for enrichment and demonstrated mild preference for the drug-associated chamber. Fecal weights and corticoid metabolite levels were similar between all groups at week 4 and showed normal diurnal variation. No biologically significant variations were noted in brain or paired adrenal gland to body weight ratios. We conclude that orogastric gavage of aqueous solutions at 5 mL/kg does not negatively affect the welfare of laboratory rats acclimated to handling. PMID:22330864

  4. [Hemicrania continua: characteristics and therapeutic experience in a series of 36 patients].

    Science.gov (United States)

    Cortijo, Elisa; Guerrero-Peral, Ángel L; Herrero-Velázquez, Sonia; Mulero, Patricia; Pedraza, María; Barón, Johanna; de la Cruz, Carolina; Ruiz, Marina; Campos-Blanco, Dulce M; Marco-Llorente, Javier; Rojo-Martínez, Esther; Fernández, Rosa

    2012-09-01

    Hemicrania continua is characterised by a continuous unilateral pain, which frequently gets worse in association with autonomic symptoms. It is probably little known and underdiagnosed. Its diagnosis requires a response to indomethacin, which is not always well tolerated. We report a series of 36 cases of hemicrania continua that were treated in the headache service of a tertiary hospital. We analyse their demographic and clinical features and the therapeutic alternatives to indomethacin. Between January 2008 and April 2012, 36 patients (28 females, eight males) were diagnosed with hemicrania continua from among 1800 (2%) who were treated in that service. The age of onset was 46.3 ± 18.4 years. In four patients (11.1%) there were pain remissions that lasted over three months. The baseline pain was chiefly oppressive or burning with an intensity of 5.2 ± 1.4 on the verbal analogue scale. Exacerbations lasted 32.3 ± 26.1 minutes, were of a predominantly stabbing nature with an intensity of 8.3 ± 1.4, and in 69.4% of cases were accompanied by autonomic symptoms. Altogether 16.7% of the patients did not tolerate indomethacin beyond an indotest and 50% did so with side effects. In 13 cases at least one anaesthetic blockade was performed in the supraorbital or the greater occipital nerve or a trochlear injection of corticoids was carried out with a full response in 53.8% and a partial response in 38.5%. Hemicrania continua is not an infrequent diagnosis in a headache clinic and, because it is a treatable condition, further knowledge on the subject is needed. Anaesthetic blockades of the supraorbital or greater occipital nerves or a trochlear injection of corticoids are the therapeutic options that must be taken into consideration when indomethacin is not well tolerated.

  5. Cure of Psoriasis and Arthritis when Addison’s Disease Was Detected

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    Marcus Lind

    2010-06-01

    Full Text Available Introduction: Corticoid therapy is well-known to improve the symptoms of psoriasis. Addison’s disease is an autoimmune disease which leads to a loss of cortisol production in the adrenal glands. This case report describes a patient with wide-spread psoriasis for 34 years who was cured when Addison’s disease was detected and substitution to reach normal biological cortisol levels was introduced. Case Report: A 59-year-old man was diagnosed with Addison’s disease. He had been tired for several years and had had difficulties in continuing his work. His brother had Addison’s disease and recommended him to make a screen for the disease. Synacthen test diagnosed Addison’s disease with a clear deficiency of cortisol production. After substitution with hydrocortisone the patient’s constitution improved rapidly and he felt no longer tired during work. At the same time, all skin lesions of psoriasis disappeared as well as aches in several joints, both symptoms having been present for a couple of decades. Previously, salves of cortisol had been used to reduce the symptoms of psoriasis, but now, 1–2 years later, after the treatment of Addison’s disease, no symptoms in the skin or joints have reoccurred. Conclusions: This report illustrates that Addison’s disease, although a rare condition, should be kept in mind before treatment of psoriasis is started. Especially if other symptoms such as fatigue are present, a screening test of serum cortisol in the morning should be liberally made. The report also illustrates a need of examining corticoid levels in patients with psoriasis compared to the general population.

  6. [Analysis of a series of cases with an initial diagnosis of acute disseminated encephalomyelitis over the period 2000-2010].

    Science.gov (United States)

    Rodríguez-Fernández, Cristina; López-Marín, Laura; López-Pino, Miguel Ángel; Gutiérrez-Solana, Luis G; Soto-Insuga, Víctor; Conejo-Moreno, David

    2013-10-01

    Acute disseminated encephalomyelitis (ADEM) is a demyelinating disease that essentially affects the white matter of the central nervous system. The diagnosis is based on clinical-imaging and developmental findings. Magnetic resonance imaging of the brain is the most useful diagnostic tool. The disease course is usually monophasic and the preferred initial treatment is with corticoids. We conducted a retrospective study of 18 patients with a presumptive diagnosis of ADEM. Symptoms, imaging findings, progress and treatment were analysed. The definitive diagnosis was established in 12 patients, excluding one patient with positive polymerase chain reaction for herpes simplex virus in cerebrospinal fluid, one with a clinical picture that was consistent but normal magnetic resonance imaging of the brain, and four with an onset that was similar to ADEM whose definitive diagnoses were: Rassmusen's syndrome, haemophagocytic syndrome, brain tumour, and MELAS (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes). The median age was 31 months with no predominance of either sex. Infection of the upper respiratory tract was the most frequent cause in children over 2 years of age and of the gastrointestinal tract in those under the age of 2. All of them presented altered levels of consciousness and multifocal neurological deficits. The most frequent imaging finding was multifocal alteration of the white matter in both hemispheres. Corticoids were the preferred treatment in most cases. Progression was favourable in nearly all patients except for two, who were left with important sequelae. ADEM may present at any age, including in infants. There are a number of conditions that can mimic ADEM in the early stages.

  7. Low-level laser therapy suppresses the oxidative stress-induced glucocorticoids resistance in U937 cells: relevance to cytokine secretion and histone deacetylase in alveolar macrophages.

    Science.gov (United States)

    Souza, N H C; Marcondes, P T; Albertini, R; Mesquita-Ferrari, R A; Fernandes, K P S; Aimbire, F

    2014-01-05

    Oxidative stress is present in severe asthma and contributes to the low response to corticoids through the downregulation of histone deacetylase (HDAC) and the increase of cytokines. Low-level laser therapy (LLLT) has been proven to be an anti-inflammatory. Thus, we investigated the laser effect on lipopolysaccharide (LPS)-induced cytokine secretion and HDAC activity in U937 cells under oxidative stress. U937 cells activated with oxidative stress were treated with dexamethasone (dexa) or laser. Cytokines and phosphoinositide 3-kinase (PI3K) were measured by ELISA whilst the HDAC was detected through colorimetric assay. LPS activated- U937 cells cytokines secretion increased with H2O2 (hydrogen peroxide) as well as with TSA (trichostatin). The HDAC activity in activated U937 cells was decreased. LLLT and dexa inhibited the LPS-stimulated U937 cells cytokines, but dexa effect disappeared with H2O2. With TSA, the LLLT was less effective on H2O2/LPS stimulated- U937 cells cytokines. Dexa failed on H2O2/LPS- induced HDAC, while LLLT restored the HDAC and the dexa effect. LLLT plus prostaglandin E2 (PGE2) increased cyclic adenosine monophosphate (cAMP) and potentiated the laser action on oxidative stress-induced cytokine. LLLT reduced the PI3K and its effects on cytokine and HDAC was suppressed with LY294002. In situations of corticoid resistance, LLLT acts decreasing the cytokines and HDAC through the activation of the protein kinase A via the inhibition of PI3K. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Cytochrome P450-mediated metabolic alterations in preeclampsia evaluated by quantitative steroid signatures.

    Science.gov (United States)

    Moon, Ju-Yeon; Moon, Myeong Hee; Kim, Ki Tae; Jeong, Dae Hoon; Kim, Young Nam; Chung, Bong Chul; Choi, Man Ho

    2014-01-01

    Although preeclampsia has been suggested potential risk factors including placental and systemic inflammation, oxidative stress, and abnormal steroid metabolism during pregnancy, the pathogenesis of preeclampsia has not fully been elucidated, particularly in steroid metabolism. The association between various cytochrome P450 (CYP)-mediated steroid metabolic markers and preeclampsia risk was therefore investigated. The serum levels of 54 CYP-mediated regioselective hydroxysteroids and their substrates were quantitatively evaluated from both pregnant women with preeclampsia (n=30; age, 30.8±4.5 years) and normotensive controls (n=30; age, 31.0±3.5 years), who were similar with respect to maternal age, gestational age, and body mass index. The levels of 6ß-, 7a-, and 11ß-hydroxymetabolites of androgens and corticoids were significantly increased in women with preeclampsia. In addition, the levels of oxysterols, including 7a-, 7ß-, 4ß-, 20a-, 24S-, and 27-hydroxycholesterol, were markedly higher, while the levels of 16a-OH-DHEA, 16a-OH-androstenedione, and cholesterol were significantly decreased in patients. The 6ß-hydroxylation of androgens and corticoids by CYP3A4 (P2.0-fold) were positively correlated with the conditions of preeclampsia. Our metabolic profiling suggests the CYP-mediated alterations in steroid metabolism and hydroxylation in pregnancy-induced hypertension. These multiple markers could serve as background information for improved clinical diagnosis and management during pregnancy. This article is part of a Special Issue entitled "Pregnancy and Steroids". Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Endocrine control of active sodium transport across frog skin; Le controle endocrinien du transport actif de sodium a travers la peau de grenouille

    Energy Technology Data Exchange (ETDEWEB)

    Maetz, J. [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1959-07-01

    I. Action of the neurohypophyseal peptides on sodium transport. 1) On Rana Esculenta, oxytocin alone is active on the sodium transport (not vaso pressin). 2) The post hypophysis of R.e. contains an hormonal factor even more specific on Na transport (12 times more active than oxytocin). 3) This new factor must be closely related to oxytocin. II. Action of the adrenal corticoids. 1) The skin of frogs adapted to a salt-rich external medium, shows a considerable diminution in sodium uptake. 2) This decreased sodium uptake is brought back to normal by the injections of aldosterone. 3) This suggests that salt loading of amphibians (as well as mammals) inhibits the mineralocorticoid activity of the adrenals. (author) [French] I. Action des peptides neurohypophysaires chez Rana esculenta. 1) Le transport actif de Na est sensible a l'action de l'ocytocine mais non a l'hormone antidiuretique. 2) La posthypophyse de ces grenouilles contient un facteur plus specifique encore, puisque 12 fois plus actif que l'ocytocine. 3) Ce facteur est cependant tres voisin de l'ocytocine au point de vue chimique. lI. Action des corticoides surrenaliens chez Rana Esculenta. 1) L'adaptation des grenouilles a un milieu riche en sel a pour effet une diminution considerable du transport actif de sodium, visible in vivo et in vitro. 2) L'injection d'aldosterone a des grenouilles adaptees dans ces conditions restaure le transport actif a un niveau comparable a celui que l'on observe chez les animaux conserves dans de l'eau courante. 3) Ces faits suggerent que la surcharge en NaCI produirait chez les amphibiens, comme chez les mammiferes, une mise au repos de la fonction mineralotrope de la surrenale. (auteur)

  10. Adolescents’ and Young Adults’ Perception of Homosexuality and Related Factors in Three Asian Cities

    Science.gov (United States)

    Feng, Yongliang; Lou, Chaohua; Gao, Ersheng; Tu, Xiaowen; Cheng, Yan; Emerson, Mark R.; Zabin, Laurie S.

    2014-01-01

    Purpose Adolescents’ and young adults’ perception of homosexuality plays an important role in the marginalization and stigmatization of the homosexual, thereby influencing his or her health. This article aims to study that perception and to examine its predictors in three Asian cities that are culturally dominated by Confucianism. Methods From May 2006 to January 2007, a cross-sectional survey of 17,016 adolescents and young adults, aged 15–24 years old, in both urban and rural sites of three Asian cities (Hanoi in Vietnam, Shanghai in the mainland of China, and Taipei in Taiwan) was conducted through interview and computer-assisted self-interview for sensitive questions. Chi-square tests and multivariate logistic regression were performed to identify the predictors for their perception of homosexuality. Results The percentage of adolescents and young adults who hold a positive view of homosexuality (i.e., thought it was normal and/or acceptable) was low, especially in Hanoi and Shanghai; these figures increased from Hanoi to Shanghai to Taipei for both males and females. Overall, those factors significantly associated with adolescents’ and young adults’ perception of homosexuality included individuals’ demographic characteristics (urban/rural, age, economic status, student status, and educational level), preferred origin of movies/videos, self-identified sexual orientation, sexual and reproductive health knowledge, family values, gender role values, and attitudes toward premarital sex. Conclusions In these three Asian cities composed of populations whose views are largely influenced by Confucianism, adolescents and young adults mainly hold a negative perception of homosexuality. The most common and important predictors for a respondent's perception of homosexuality were his or her knowledge of sexual and reproductive health and how traditional his/her values may be. Greater attention needs to be paid to the popularization of knowledge about sexual and

  11. Study of the correlations between fractional exhaled nitric oxide in exhaled breath and atopic status, blood eosinophils, FCER2 mutation, and asthma control in Vietnamese children

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    Nguyen-Thi-Bich H

    2016-09-01

    Full Text Available Hanh Nguyen-Thi-Bich,1 Huong Duong-Thi-Ly,2 Vu Thi Thom,2 Nhung Pham-Thi-Hong,2 Long Doan Dinh,2 Huong Le-Thi-Minh,1 Timothy John Craig,3 Sy Duong-Quy3,4 1Department of Immunology, Allergology, and Rheumatology, National Hospital of Pediatrics, Hanoi, Vietnam; 2School of Medicine and Pharmacy, Vietnam National University Hanoi, Vietnam; 3Department of Medicine, Penn State University, Hershey, PA, USA; 4Department of Respiratory Diseases, Lam Dong Medical College, Dalat, Vietnam Introduction: Fractional exhaled nitric oxide (FENO is a biomarker of airway inflammation in asthma. The measurement of FENO is utilized to assist in the diagnosis and treatment of children with asthma, especially for those treated with inhaled corticosteroids. Objectives: The aims of this study were to evaluate the correlations between FENO and atopic status, blood eosinophil levels, FCER2 mutation, and asthma control in Vietnamese children. Subjects and methods: This was a prospective and descriptive study approved by the local Ethical Board. All children with uncontrolled asthma, seen in the National Hospital of Pediatrics (Hanoi, Vietnam, were included. Exhaled breath FENO, blood eosinophils, skin prick test, total IgE, asthma control test (ACT, and FCER2 gene polymorphism were performed at inclusion. They were followed up at 3 months to evaluate clinical status, FENO levels, and ACT. Results: Forty-two children with uncontrolled asthma with a mean age of 10±3 years (6–16 years were included. The male/female ratio was 2.5/1. The mean FENO levels were 26±25 ppb. FENO was significantly higher in patients with a positive skin prick test for respiratory allergens (P<0.05. FENO was significantly correlated with blood eosinophil levels (r=0.5217; P=0.0004. Five of the 32 subjects (15.6% had a mutation of FCER2 gene (rs28364072 SNP. In this group, the levels of FENO were highest (37±10 ppb; P<0.05. The levels of FENO were significantly decreased after 3 months of

  12. Adolescents' and young adults' perception of homosexuality and related factors in three Asian cities.

    Science.gov (United States)

    Feng, Yongliang; Lou, Chaohua; Gao, Ersheng; Tu, Xiaowen; Cheng, Yan; Emerson, Mark R; Zabin, Laurie S

    2012-03-01

    Adolescents' and young adults' perception of homosexuality plays an important role in the marginalization and stigmatization of the homosexual, thereby influencing his or her health. This article aims to study that perception and to examine its predictors in three Asian cities that are culturally dominated by Confucianism. From May 2006 to January 2007, a cross-sectional survey of 17,016 adolescents and young adults, aged 15-24 years old, in both urban and rural sites of three Asian cities (Hanoi in Vietnam, Shanghai in the mainland of China, and Taipei in Taiwan) was conducted through interview and computer-assisted self-interview for sensitive questions. Chi-square tests and multivariate logistic regression were performed to identify the predictors for their perception of homosexuality. The percentage of adolescents and young adults who hold a positive view of homosexuality (i.e., thought it was normal and/or acceptable) was low, especially in Hanoi and Shanghai; these figures increased from Hanoi to Shanghai to Taipei for both males and females. Overall, those factors significantly associated with adolescents' and young adults' perception of homosexuality included individuals' demographic characteristics (urban/rural, age, economic status, student status, and educational level), preferred origin of movies/videos, self-identified sexual orientation, sexual and reproductive health knowledge, family values, gender role values, and attitudes toward premarital sex. In these three Asian cities composed of populations whose views are largely influenced by Confucianism, adolescents and young adults mainly hold a negative perception of homosexuality. The most common and important predictors for a respondent's perception of homosexuality were his or her knowledge of sexual and reproductive health and how traditional his/her values may be. Greater attention needs to be paid to the popularization of knowledge about sexual and reproductive health including homosexuality

  13. Potential for the development of a marketing option for the specialty local Ban pork of a Thai ethnic smallholder cooperative group in Northwest Vietnam.

    Science.gov (United States)

    Le, Thi Thanh Huyen; Muth, Philipp C; Markemann, André; Schöll, Kerstin; Zárate, Anne Valle

    2016-02-01

    Based on 12 years of research (SFB 564 "The Uplands Program"), a community-based breeding and marketing cooperative group was transferred to an ethnic farmer group. This study analyses the potential for developing a marketing channel for specialty local Ban pork as an alternative to supplying the local markets to ensure long-term sustainability of the communal local pig breeding and production system. Data on pig-keeping were investigated from 378 farmers who wanted to enroll in the cooperative group in 10 villages (near town, intermediate, and remote zones) in Son La province. The data on Ban pig marketing activities of the cooperative group were investigated for all of its 180 members. Information on the market demand for Ban pigs were collected by interviewing 57 traders in Hanoi city and Son La province. The results show a dominance of local Ban in remote areas, and a preference for crossbreds with exotics in closer-to-town areas. Before farmers joined the cooperative group, the commercialization of pigs in remote villages accounted for only 3.0 pigs/farm/year compared to 9.3 pigs/farm/year in the intermediate zone and 11.2 pigs/farm/year near town. Potential markets have been identified for each product category of the cooperative group. Pure Ban pigs with a weight of 10-15 kg were preferred most by customers in Hanoi city. The regular feedback of information on niche markets for different products has increased the awareness of farmers about the competitiveness of the local pig products, and the power of collective action in the market. Selected pure Ban pigs were increasingly sold to food stores in Hanoi with high prices. Farmers received an average of 9000 VND more compared to the local market price for each kg of live weight. The respective added value for the cooperative group amounted to 11,300 VND/kg live weight. The added value from selling specialty Ban pigs regularly to markets, encouraged farmers toward a market in local pig production and

  14. Resposta da alface à adubação nitrogenada com diferentes compostos orgânicos em dois ciclos sucessivos = Response of lettuce to nitrogen fertilization with different organic composts in two successive cycles

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    Francisca Alcivania de Melo Silva

    2010-01-01

    Full Text Available Os objetivos deste trabalho foram avaliar a produção de alface em ambiente protegido, utilizando diferentes compostos orgânicos como fonte de nitrogênio, e seu efeito residual em dois ciclos sucessivos. O experimento foi conduzido entre os meses de fevereiro e maio de 2005, em casa-de-vegetação com ventilação e temperatura controlados, utilizando vasos de 3,5 L e solo classificado como Latossolo Vermelho Escuro. Foram utilizados compostos orgânicos produzidos a partir da mistura de resíduos do processamento de quatro plantas medicinais e esterco bovino. Os compostos C1, C2, C3 e C4 nas doses 30, 60, 90 e 120 t ha-1 constituíram os tratamentos dispostos em delineamento inteiramente casualizado, com quatro repetições e uma testemunha (adicional. Foram determinados: matéria fresca da parte aérea (MFPA; massa de matéria seca da parte aérea (MSPA. Os compostos aplicados supriram satisfatoriamente as necessidades de nitrogênio da cultura, no primeiro ciclo, dispensando o uso de fertilizante mineral. A composição dos materiais aplicados influenciou significativamente a produção de alface no primeiro ciclo, promovendo efeito residual no segundo ciclo, porém em menores proporções.The objectives of this work were to evaluate the production of lettuce in a protected environment, using different organic composts as nitrogen source and its residual effect in two successive cycles. The experiment was conducted between February and May of 2005, at a greenhouse with controlled ventilation and temperature, using 3.5 L vases and ground classified as Dark Red Latossol. Organic composts produced from the mixture of residues of the processing of four medicinal plants and cattle manure were used. The composts C1, C2, C3 and C4 in doses 30, 60, 90 and 120 t ha-1 composed the treatments, set in an entirely randomized design, with four repetitions and one control (additional treatment. The following were determined: freshmatter of aerial part

  15. Cola terapêutica de cianoacrilato nas perfurações corneanas Therapeutic cyanoacrylate glue for corneal perforations

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    Cristina Garrido

    1999-12-01

    Full Text Available Objetivo: Avaliar indicações, evolução e complicações do uso do adesivo de cianoacrilato no tratamento dos afinamentos e perfurações corneanas. Material e Métodos: Vinte e seis olhos de 26 pacientes portadores de afinamento ou perfuração corneana (£ 2,5 mm de diâmetro receberam adesivo tecidual à base de metil 2-cianoacrilato e, a seguir, lente de contato terapêutica hidrofílica sobre a área colada. Resultados: Entre as indicações para aplicação do adesivo de cianoacrilato, detectaram-se 12 (46% casos de perfuração corneana causada por úlcera de córnea infecciosa. Dos 26 olhos que receberam adesivo, 15 (57,7% necessitaram de uma única aplicação e 11 (42,3% de duas aplicações. Houve evolução para leucoma corneano após desprendimento da cola em 13 (50% olhos; necessidade de intervenção cirúrgica em 4 (15% e permanência da cola em 9 (35%. A acuidade visual manteve-se inalterada em 15 (57,7% olhos, melhorou em 7 (27% e diminuiu em 4 (15,3%. Conclusões: O adesivo de cianoacrilato pode ser usado com sucesso no tratamento imediato dos afinamentos e perfurações corneanas, prorrogando ou até mesmo dispensando um futuro procedimento cirúrgico.Purpose: To investigate the indications, outcomes and complications of cyanoacrylate tissue adhesive for stromal thinning and corneal perforations. Methods: Twenty-six eyes of 26 patients with stromal thinning or corneal perforations (£ 2.5 mm received methyl 2-cya-noacrylate adhesive and bandage contact lens. Results: Twelve cases (46% of corneal perforation were caused by infectious ulcer. For the 26 eyes that received adhesive, 15 (57.7% needed only one application of the glue and 11 (42.3% needed two applications. Thirteen eyes (50% developed for leukoma; 4 (15% needed surgery and 9 (35% eyes remained sealed. Visual acuity remained unaltered in 15 eyes (57.7%, improved in 7 (27% and got worse in 4 (15.3% eyes. Conclusion: The cyanoacrylate adhesive is available to all

  16. Prostituição juvenil feminina e a prevenção da Aids em Ribeirão Preto, SP

    Directory of Open Access Journals (Sweden)

    Cristiane Paulin Simon

    2002-08-01

    Full Text Available OBJETIVOS: Investigar as percepções sobre a Aids para o desenvolvimento de programas de prevenção de Aids com a prostituição juvenil feminina. MÉTODOS: Foram entrevistadas 13 jovens com idades entre 18 e 21 anos, que trabalham como prostitutas na cidade de Ribeirão Preto, por meio de um roteiro semi-estruturado com questões referentes a: dados sociodemográficos; conhecimentos sobre Aids; comportamentos sexuais; tipos de relacionamentos com clientes, namorados ou companheiros; e sugestões para programas de prevenção de doenças sexualmente transmissíveis (DST e Aids. RESULTADOS: Embora todas as entrevistadas tenham demonstrado conhecimento sobre HIV e práticas sexuais seguras, essas informações se contradizem com a crença no destino como o determinante para a infecção pelo HIV, bem como com a busca de afetividade nos relacionamentos, seja com o companheiro, namorado ou cliente fixo. Essas contradições agem como possíveis fatores impeditivos para adoção de comportamentos preventivos consistentes. CONCLUSÕES: As estratégias de prevenção para o HIV e a Aids devem levar em consideração que é necessário criar espaços nos quais se possibilitem a discussão e reflexão, que facilitem a clarificação de crenças e concepções que ainda fazem parte do imaginário social desse segmento social sobre a Aids. Também são necessárias discussões sobre os envolvimentos afetivos que são percebidos como relacionamentos imunes, dispensando a negociação de práticas preventivas. Outro ponto fundamental é o tipo de abordagem a ser utilizado para contatar as jovens. Estratégias sensíveis às características das jovens deverão ser empregadas.

  17. Prostituição juvenil feminina e a prevenção da Aids em Ribeirão Preto, SP

    Directory of Open Access Journals (Sweden)

    Simon Cristiane Paulin

    2002-01-01

    Full Text Available OBJETIVOS: Investigar as percepções sobre a Aids para o desenvolvimento de programas de prevenção de Aids com a prostituição juvenil feminina. MÉTODOS: Foram entrevistadas 13 jovens com idades entre 18 e 21 anos, que trabalham como prostitutas na cidade de Ribeirão Preto, por meio de um roteiro semi-estruturado com questões referentes a: dados sociodemográficos; conhecimentos sobre Aids; comportamentos sexuais; tipos de relacionamentos com clientes, namorados ou companheiros; e sugestões para programas de prevenção de doenças sexualmente transmissíveis (DST e Aids. RESULTADOS: Embora todas as entrevistadas tenham demonstrado conhecimento sobre HIV e práticas sexuais seguras, essas informações se contradizem com a crença no destino como o determinante para a infecção pelo HIV, bem como com a busca de afetividade nos relacionamentos, seja com o companheiro, namorado ou cliente fixo. Essas contradições agem como possíveis fatores impeditivos para adoção de comportamentos preventivos consistentes. CONCLUSÕES: As estratégias de prevenção para o HIV e a Aids devem levar em consideração que é necessário criar espaços nos quais se possibilitem a discussão e reflexão, que facilitem a clarificação de crenças e concepções que ainda fazem parte do imaginário social desse segmento social sobre a Aids. Também são necessárias discussões sobre os envolvimentos afetivos que são percebidos como relacionamentos imunes, dispensando a negociação de práticas preventivas. Outro ponto fundamental é o tipo de abordagem a ser utilizado para contatar as jovens. Estratégias sensíveis às características das jovens deverão ser empregadas.

  18. Avaliação de métodos para quebra da dormência e para a desinfestação de sementes de canafístula (Peltophorum dubium (Sprengel Taubert

    Directory of Open Access Journals (Sweden)

    Oliveira Luciana Magda de

    2003-01-01

    Full Text Available Este trabalho teve como objetivo testar a eficiência de diferentes tratamentos para quebra da dormência e desinfestação de sementes de canafístula na realização do teste de germinação. O experimento foi realizado em esquema fatorial com três lotes × cinco tratamentos para quebra da dormência × quatro tratamentos de desinfestação das sementes. As sementes utilizadas foram coletadas nos municípios de Lavras-MG, em 1986 e 1998, e em Lins-SP, em 1998. Os tratamentos para quebra da dormência foram constituídos por escarificação manual com lixa, água quente (a- fervura das sementes por 3 minutos com imersão por 24 horas, fora do aquecimento; e b - imersão das sementes em água quente por 24 horas, fora do aquecimento e ácido sulfúrico (imersão por 15, 17, 20 e 30 minutos. Para desinfestação das sementes foram testados os tratamentos, utilizando Polyfluanide (0,2% por 30 minutos, Benomyl (0,02% por 1 minuto e hipoclorito de sódio (2% por 3 minutos. Foram utilizadas quatro repetições de 25 sementes em cada tratamento. O teste de germinação foi instalado sobre areia, na temperatura de 25 ºC, sob luz branca constante. As contagens de germinação (plântulas normais foram realizadas diariamente. O tratamento de imersão das sementes de canafístula em água quente (95 ºC e posterior permanência na mesma água por mais 24 horas, fora do aquecimento, é eficiente na promoção da germinação, sendo prático e dispensando o uso de tratamentos de desinfestação.

  19. Interação entre cultivares, estirpes comerciais de Rhizobium meliloti e fungicidas no incremento da produção de alfafa Interactions of cultivars, commercial strains of Rhizobium meliloti and fungicides on the production of alfalfa

    Directory of Open Access Journals (Sweden)

    Patrícia Perondi Anchão Oliveira

    1999-03-01

    Full Text Available A cultura da alfafa (Medicago sativa é importante para a produção animal, por sua alta qualidade nutritiva, alto potencial de produção e sucesso na fixação de nitrogênio, através da simbiose com o Rhizobium meliloti, dispensando o uso de adubação nitrogenada. Neste trabalho objetivou-se selecionar estirpes comerciais de R. meliloti (SEMIA-116, SEMIA-134 e SEMIA-135 em relação às cultivares de alfafa Flórida 77, Pioneer 5929, CUF 101 e Crioula, e avaliar os fungicidas Iprodione e Thiram em tratamento de semente e solo na cultivar Crioula. Não houve interação entre as estirpes de R. meliloti e as cultivares de alfafa quanto à produção de matéria seca, e as plantas infestadas com a SEMIA-116 apresentaram maior número de nódulos. Houve interações entre os diferentes tipos e doses de fungicidas e as estirpes de R. meliloti testadas. A estirpe SEMIA-116 apresentou superioridade, representada pela maior produção de biomassa e número de nódulos. Pelos resultados obtidos, não se recomenda a inoculação da estirpe SEMIA-135, quando em associação com o fungicida Iprodione, em solo ou semente.The cultivation of alfalfa (Medicago sativa is not only important because of its nutrient, content, but also for its high productivity and its ability to fix nitrogen through its association with Rhizobium meliloti. To better understand this symbiotic association, the interaction between R. meliloti strains SEMIA-116, SEMIA-134 and SEMIA-135 with different cultivars of alfalfa Florida 77, Pioneer 5929, CUF 101 and Crioula was evaluated. In addition to the above treatments, the fungicides Iprodione and Thiram were used with the cultivar Crioula to study their effects on the alfalfa/Rhizobium interaction. Plants inoculated with SEMIA-116 had a greater number of nodules. However, no significant difference in the production of plant dry matter was observed between the various Rhizobium strains and the alfalfa cultivars tested. In the

  20. Fisica a escala de Planck usando o principio de incerteza generalizado: efeitos nas flutuações primordiais e buracos negros

    Science.gov (United States)

    Horvath, J. E.; Custódio, P. S.

    2003-08-01

    Em escalas proximas à escala de Planck todas as teorias perturbativas de cordas produzem essenciamente a mesma relação de conmutação entre as coordenadas e impulsos (a chamada "álgebra deformada"), permitindo assim estudar a física resultante independentemente dos detalhes da teoria de cordas que seja considerada correta. Este resultado completamente geral, que inclui as interações gravitacionais junto com o resto dos campos pode ser considerada uma versão generalizada (GUP) do Princípio de Incerteza de Heisenberg. Aplicamos neste trabalho essas relações de conmutação para dois sistemas físicos bem definidos: buracos negros de massas próximas à massa de Planck, e flutuações quânticas em pequenas escalas antes do universo sofrer inflação. Obtemos dois resultados concretos dos efeitos do GUP : o primeiro é que o GUP impede a evaporação completa de buracos negros microscópicos na extensão do formalismo semiclássico, deixando assim remanescentes de pequena massa que já foram postulados como candidatos a matéria escura. O segundo resultado é o 'smoothing' das flutuações primordiais em pequenas escalas que levariam à produção de buracos negros primordiais após a inflação, impedindo assim a produção abundante destes últimos e predizendo abundancias atuais bem menores do que os limites disponíveis. Concluimos que, analogamente a utilização do Princípio de Incerteza de Heisenberg para estudar e determinar propriedades fundamentais das interações sem gravitação, o GUP e uma ferramenta poderosa para estudar uma ampla variedade de sistemas trans-Planckianos e predizer seu comportamento dispensando cálculos mais detalhados proprios da teoria quântica da gravitação.

  1. Lack of executive functions deficits among adult ad hd individuals from a Brazilian clinical sample

    Science.gov (United States)

    Saboya, Eloisa; Coutinho, Gabriel; Segenreich, Daniel; Ayrão, Vanessa; Mattos, Paulo

    2009-01-01

    Executive function deficits have been previously documented in individuals with Attention Deficit Hyperactivity Disorder (ADHD). Objective The current study aimed to compare measures of executive functions among a clinical sample of adults with ADHD and normal control subjects, matched for age, gender and education. Methods Twenty-three self-referred adults diagnosed with ADHD according to DSM-IV criteria, and twenty-five control subjects were assessed using a neuropsychological battery which included the Wisconsin Card Sorting Test, Tower of Hanoi, Digit Span, Trail Making Test (A and B), Stroop Test and Raven’s Progressive Matrices. Results The ADHD group did not differ significantly from the control subjects on any of the measures assessed. Conclusion Measures of executive functions using this test battery were unable to discriminate between adults with ADHD and control subjects in this clinical sample. PMID:29213607

  2. 6th International Conference on High Performance Scientific Computing

    CERN Document Server

    Phu, Hoang; Rannacher, Rolf; Schlöder, Johannes

    2017-01-01

    This proceedings volume highlights a selection of papers presented at the Sixth International Conference on High Performance Scientific Computing, which took place in Hanoi, Vietnam on March 16-20, 2015. The conference was jointly organized by the Heidelberg Institute of Theoretical Studies (HITS), the Institute of Mathematics of the Vietnam Academy of Science and Technology (VAST), the Interdisciplinary Center for Scientific Computing (IWR) at Heidelberg University, and the Vietnam Institute for Advanced Study in Mathematics, Ministry of Education The contributions cover a broad, interdisciplinary spectrum of scientific computing and showcase recent advances in theory, methods, and practical applications. Subjects covered numerical simulation, methods for optimization and control, parallel computing, and software development, as well as the applications of scientific computing in physics, mechanics, biomechanics and robotics, material science, hydrology, biotechnology, medicine, transport, scheduling, and in...

  3. Manure management practices on biogas and non-biogas pig farms in developing countries - using livestock farms in Vietnam as an example

    DEFF Research Database (Denmark)

    Cu, T. T. T.; Cuong, P. H.; Hang, L. T.

    2012-01-01

    This survey was carried out to study animal manure management on livestock farms with biogas technology (biogas farms) and without (non-biogas farms) in the areas surrounding the Vietnamese cities Hanoi and Hue. The objective of the study was to assess the contribution of biogas production...... to a better environment as well as to recognize the problems with livestock manure management on small-scale farms. On all the farms included in the study more than one manure management technology was used, i.e. composting, separation of manure, biogas production and discharge of liquid manure to recipients...... such as public sewers or ponds. On biogas farms, most of the manure collected was used for bio-digestion. The farmers used the fermented manure (digestate) as a source of nutrients for crops, but on more than 50% of the interviewed biogas farms digestate was discharged to the environment. On non-biogas farms...

  4. The Relations between Television Exposure and Executive Function in Chinese Preschoolers: The Moderated Role of Parental Mediation Behaviors.

    Science.gov (United States)

    Yang, Xiaohui; Chen, Zhe; Wang, Zhenhong; Zhu, Liqi

    2017-01-01

    The present study examined the relations between preschoolers' television exposure and executive functions (EF). One hundred and nineteen 3- to 6-year-old children and their parents participated. Parents filled in a questionnaire regarding children's television viewing time, television content and parental mediation behaviors about their child's television viewing. The children were asked to finish six EF tasks, including the backward digit span task, the spatial span task, the boy-girl Stroop, the Simon task, the flanker task and the Tower of Hanoi task that assessed working memory, inhibition and planning, respectively. Children's vocabulary was tested using Peabody Picture Vocabulary Test, and included as control variables in addition to socioeconomic status of the participated families. The results showed that television viewing time and child-directed educational programs were positively associated with EF. In addition, television content fully mediated the effect of television viewing time on EF and parental restrictive approach strategies moderated the effect of television viewing time on EF.

  5. Psychology of computer use: X. Effect of learning Logo on children's problem-solving skills.

    Science.gov (United States)

    Poulin-Dubois, D; McGilly, C A; Shultz, T R

    1989-06-01

    A natural experiment was used to determine whether learning the computer language Logo improves children's problem-solving strategies outside of the Logo context. 8-yr.-olds who learned Logo in school were found to use both debugging techniques and procedurality in their computer programming. They and a group of control children of the same age were pre- and posttested on a game requiring debugging skills (Mastermind) and another game requiring procedural skills (Tower of Hanoi). Boys, but not girls, trained in Logo showed an improvement in debugging skills relative to the control children. Improvement in procedural skills was not related to training in Logo. The results were discussed in terms of distance of transfer, degree of expertise, and the basis of sex differences in computer programming.

  6. Improved mine blast algorithm for optimal cost design of water distribution systems

    Science.gov (United States)

    Sadollah, Ali; Guen Yoo, Do; Kim, Joong Hoon

    2015-12-01

    The design of water distribution systems is a large class of combinatorial, nonlinear optimization problems with complex constraints such as conservation of mass and energy equations. Since feasible solutions are often extremely complex, traditional optimization techniques are insufficient. Recently, metaheuristic algorithms have been applied to this class of problems because they are highly efficient. In this article, a recently developed optimizer called the mine blast algorithm (MBA) is considered. The MBA is improved and coupled with the hydraulic simulator EPANET to find the optimal cost design for water distribution systems. The performance of the improved mine blast algorithm (IMBA) is demonstrated using the well-known Hanoi, New York tunnels and Balerma benchmark networks. Optimization results obtained using IMBA are compared to those using MBA and other optimizers in terms of their minimum construction costs and convergence rates. For the complex Balerma network, IMBA offers the cheapest network design compared to other optimization algorithms.

  7. 'I thought I was the only one': the misrecognition of LGBT youth in contemporary Vietnam.

    Science.gov (United States)

    Horton, Paul

    2014-01-01

    While recent LGBT rights demonstrations and discussions about same-sex marriage have thrust the issue of homosexuality into the spotlight, it was not long ago that the issue of homosexuality was notable by its absence in Vietnam. Drawing on semi-structured interviews with young gay, lesbian and bisexual people in Vietnam's capital city Hanoi, this paper considers the increasing visibility of homosexuality through the theoretical lens of recognition, and illustrates the heterosexist misrecognition that LGBT young people have been subjected to in legislation, the media, their families, and through the education system. Drawing on the narratives of LGBT young people, the paper highlights the potentially negative impact such misrecognition may have on psychological and social wellbeing.

  8. Fifth International Conference KSE 2013

    CERN Document Server

    Denoeux, Thierry; Tran, Dang; Le, Anh; Pham, Son; Knowledge and Systems Engineering

    2014-01-01

    The field of Knowledge and Systems Engineering (KSE) has experienced rapid development and inspired many applications in the world of information technology during the last decade. The KSE conference aims at providing an open international forum for presentation, discussion and exchange of the latest advances and challenges in research of the field. These proceedings contain papers presented at the Fifth International Conference on Knowledge and Systems Engineering (KSE 2013), which was held in Hanoi, Vietnam, during 17–19 October, 2013. Besides the main track of contributed papers, which are compiled into the first volume, the conference also featured several special sessions focusing on specific topics of interest as well as included one workshop, of which the papers form the second volume of these proceedings. The book gathers a total of 68 papers describing recent advances and development on various topics including knowledge discovery and data mining, natural language processing, expert systems, intell...

  9. Knowledge Transfer Channels to Vietnam for Process Improvement

    DEFF Research Database (Denmark)

    Machikita, Tomohiro; Ueki, Yasushi

    2013-01-01

    -supplier relationships that cause gaps in quality assurance, cost reduction, and timely delivery among firms in emerging countries. Design/methodology/approach The authors constructed an original dataset on production networks within manufacturing firms in Vietnam (including Hanoi and the surrounding region...... between two firms within a production chain via resident engineers significantly explains the variation in performance of total quality management among firms in Vietnam under controlling vertical ownership within a chain. Since the authors could find no significant correlations between transactions......) and estimated statistical models for the relationship between face-to-face interactions within a supply chain and QCD (Quality, Cost, Delivery). Findings from in-depth interviews with Japanese firms in emerging economies complement the quantitative analysis. Findings The incidence of face-to-face interactions...

  10. Destination Culture and Its Influence on Tourist Motivation and Tourist Satisfaction of Homestay Visit

    Directory of Open Access Journals (Sweden)

    Nguyen Quang VINH

    2013-12-01

    Full Text Available With the advantage of culture and historical tourism resource, Hanoi has to finalize its tourism development strategy for the long term. This study aims to help tourism planners and marketers to get an understanding that may provide a foundation for their strategic marketing decision in homestay tourism service. The empirical analysis used data from 150 international visitors who have experience in using homestay service in Duonglam old village. To test the hypotheses among tourist motivation, satisfaction with destination loyalty, regression is adopted. This study result show that climate conditions, the destination can be easily reached, the quality of the accommodation, beauty of the scenery and cleanliness are ranked most important attribute for tourist satisfaction with Duonglam village. Another hand the result also indicates negative image about tourist service and culture events of Duonglam old village. Implications of the findings for tourism marketers and research limitation are also discussed.

  11. Lack of executive function deficits among adult ADHD individuals from a Brazilian clinical sample

    Directory of Open Access Journals (Sweden)

    Eloisa Saboya

    Full Text Available Abstract Executive function deficits have been previously documented in individuals with Attention Deficit Hyperactivity Disorder (ADHD. Objective: The current study aimed to compare measures of executive functions among a clinical sample of adults with ADHD and normal control subjects, matched for age, gender and education. Methods: Twenty-three self-referred adults diagnosed with ADHD according to DSM-IV criteria, and twenty-five control subjects were assessed using a neuropsychological battery which included the Wisconsin Card Sorting Test, Tower of Hanoi, Digit Span, Trail Making Test (A and B, Stroop Test and Raven's Progressive Matrices. Results: The ADHD group did not differ significantly from the control subjects on any of the measures assessed. Conclusion: Measures of executive functions using this test battery were unable to discriminate between adults with ADHD and control subjects in this clinical sample.

  12. A general method for computing Tutte polynomials of self-similar graphs

    Science.gov (United States)

    Gong, Helin; Jin, Xian'an

    2017-10-01

    Self-similar graphs were widely studied in both combinatorics and statistical physics. Motivated by the construction of the well-known 3-dimensional Sierpiński gasket graphs, in this paper we introduce a family of recursively constructed self-similar graphs whose inner duals are of the self-similar property. By combining the dual property of the Tutte polynomial and the subgraph-decomposition trick, we show that the Tutte polynomial of this family of graphs can be computed in an iterative way and in particular the exact expression of the formula of the number of their spanning trees is derived. Furthermore, we show our method is a general one that is easily extended to compute Tutte polynomials for other families of self-similar graphs such as Farey graphs, 2-dimensional Sierpiński gasket graphs, Hanoi graphs, modified Koch graphs, Apollonian graphs, pseudofractal scale-free web, fractal scale-free network, etc.

  13. Factors associated with self-medication among medicine sellers in urban Vietnam.

    Science.gov (United States)

    Nguyen, Huy Van; Nguyen, Thi Hong Ngoc

    2015-01-01

    In Vietnam, many medicine sellers serving pharmacies and retail outlets do not have adequate professional qualifications, and there has been a limited institutional control. The objective of this cross-sectional study was to examine the prevalence and determinants of self-medication among medicine sellers in Hanoi, Vietnam. Although 96.55% of medicine sellers had relatively serious health problems, only 61.21% visited a healthcare facility, though self-medication was moderately high (approximately 39%). Adopting Andersen's conceptual model, it was identified that medicine sellers who reported higher professional education, had low confidence in healthcare services, had not received any professional in-service during the prior year, had less serious health problems and who perceived the current costs of healthcare as too high were more likely to report self-medication. The findings have public health policy implications for these healthcare providers in urban Vietnam and other similar developing countries. Copyright © 2013 John Wiley & Sons, Ltd.

  14. 5th International Conference on High Performance Scientific Computing

    CERN Document Server

    Hoang, Xuan; Rannacher, Rolf; Schlöder, Johannes

    2014-01-01

    This proceedings volume gathers a selection of papers presented at the Fifth International Conference on High Performance Scientific Computing, which took place in Hanoi on March 5-9, 2012. The conference was organized by the Institute of Mathematics of the Vietnam Academy of Science and Technology (VAST), the Interdisciplinary Center for Scientific Computing (IWR) of Heidelberg University, Ho Chi Minh City University of Technology, and the Vietnam Institute for Advanced Study in Mathematics. The contributions cover the broad interdisciplinary spectrum of scientific computing and present recent advances in theory, development of methods, and practical applications. Subjects covered include mathematical modeling; numerical simulation; methods for optimization and control; parallel computing; software development; and applications of scientific computing in physics, mechanics and biomechanics, material science, hydrology, chemistry, biology, biotechnology, medicine, sports, psychology, transport, logistics, com...

  15. Arsenic in groundwater of the Red River floodplain, Vietnam: Controlling geochemical processes and reactive transport modeling

    DEFF Research Database (Denmark)

    Postma, Diederik Jan; Larsen, Flemming; Hue, N.T.M.

    2007-01-01

    The mobilization of arsenic (As) to the groundwater was studied in a shallow Holocene aquifer on the Red River flood plain near Hanoi, Vietnam. The groundwater chemistry was investigated in a transect of 100 piezometers. Results show an anoxic aquifer featuring organic carbon decomposition......(III) but some As(V) is always found. Arsenic correlates well with NH4, relating its release to organic matter decomposition and the source of As appears to be the Fe-oxides being reduced. Part of the produced Fe(II) is apparently reprecipitated as siderite containing less As. Results from sediment extraction...... indicate most As to be related to the Fe-oxide fractions. The measured amount of sorbed As is low. In agreement, speciation calculations for a Fe-oxide surface suggest As(III) to constitute only 3% of the surface sites while the remainder is occupied by carbonate and silica species. The evolution in water...

  16. Pierre Darriulat is awarded the André Lagarrigue Prize

    CERN Multimedia

    2009-01-01

    Pierre Darriulat at the VATLY Laboratory in Hanoï. Former CERN Research Director, Pierre Darriulat, who is now Professor of Physics at VATLY in Hanoi (Vietnam), has won the 2008 André Lagarrigue Prize. This prize, instituted by the Linear Accelerator Laboratory (LAL) at Orsay under the aegis of the French Physical Society, is awarded to front-line researchers who have had responsibility for machine/detector construction and derived maximum scientific benefit from such projects, performed in a French laboratory or in close collaboration with French groups. Pierre Darriulat has received the award in recognition of his outstanding career at the CEA, at LBL (Berkeley) and at CERN from 1964 onwards. At CERN he managed the experiments at the Intersecting Storage Rings (ISR) before taking charge of the UA2 collaboration from 1980 to 1986, which participated in decisive discoveries at the ppbar collider. In particular, in 1982, the UA2 experiment began observing high trans...

  17. Civil society organisations' roles in health development in Vietnam: HIV as a case study.

    Science.gov (United States)

    Hoang, Tu-Anh

    2013-01-01

    Civil society in contemporary Vietnam has been recognised as an important force in public health. Based on qualitative interviews and observations of 30 organisations and networks in Hanoi and Ho Chi Minh City, this paper argues that civil society organisations (CSOs) focus almost exclusively on providing information and services, including care and treatment, in line with a state-sanctioned 'implementer' role for civil society, and that these organisations therefore miss an opportunity to act as agents for change. It was observed that the CSOs taking on roles involving advocacy and the monitoring of policy implementation were those that focus exclusively on HIV/AIDS prevention and control. However, the sustainability of these efforts is unclear.

  18. Waste Municipal Service and Informal Recycling Sector in Fast-Growing Asian Cities: Co-Existence, Opposition or Integration?

    Directory of Open Access Journals (Sweden)

    Rémi de Bercegol

    2017-12-01

    Full Text Available Despite being generally poorly recognized by public authorities, informal recycling remains nevertheless a major component in the waste sector, which questions the legitimacy of the official waste arrangements. A look at the current transformation in Hanoi (Vietnam, Delhi (India and Surabaya (Indonesia allows us to understand the socio-technical aspects of infrastructural choices in the management of waste generated in fast-growing Asian cities. The three cases present similar traditional recycling practices yet contrasted (non- regulation within their waste policies. From the co-existence of a municipal waste management service with a traditional informal recycling sector, to an opposition between both, there is also a possibility of making use of the existing local practices to achieve a more sustainable system.

  19. Migrant beer promoters' experiences accessing reproductive health care in Cambodia, Laos, Thailand, and Vietnam: lessons for planners and providers.

    Science.gov (United States)

    Webber, Gail C; Spitzer, Denise L; Somrongthong, Ratana; Dat, Truong Cong; Kounnavongsa, Somphone

    2015-03-01

    Migrant beer promoters in Cambodia, Laos, Thailand, and Vietnam were surveyed to determine their experiences in accessing reproductive health care services in the cities of Phnom Penh, Vientiane, Bangkok, and Hanoi. A total of 7 health care institutions were chosen as popular with migrant beer promoters. Staff at these institutions provided information on the institution, and 390 beer promoters were surveyed about their experiences while accessing services. There were discrepancies between findings from the staff interviews and the experiences of the beer promoters. In general, the migrant women were satisfied with the cost, location, friendliness of the health care providers, and knowledge and skills of the providers. They were less positive about confidentiality and waiting times, though many still agreed that these were not an issue. Health care planners and providers should take note of the issues affecting access to reproductive health care services for migrant women when they design and implement services. © 2012 APJPH.

  20. Business Development of Solid Waste Treatment Technology and Bio-Fertilizer Production through a Danish-Vietnamese Partnership

    DEFF Research Database (Denmark)

    Christensen, David

    , legislative and market context. The findings are useful for researchers and practitioners within the waste sector in Southeast Asian countries. The partnership’s business concept deals with the proposed introduction of improved Danish solid waste separation and treatment technology at a plant in one...... of the outlying suburbs of the Vietnamese capital city of Hanoi, which is dimensioned to be able to treat 30,000 tons municipal solid waste per year. The technology in question involves the highly refined separation of the organic waste fraction into so-called bio-pulp, which only has a 0,01% content of plastic......This paper narrates the process and outcome of the business development maturation phase of a partnership between Danish and Vietnamese businesses in the waste management sector that began in early 2011 and is ongoing. The partnership has been initially facilitated by a university-based support...

  1. A Danish-Vietnamese Partnership for Business and Technology Development in Solid Waste Management

    DEFF Research Database (Denmark)

    Christensen, David; Bach, Leu Tho

    2015-01-01

    of these partnerships. The partnership's business concept deals with the proposed introduction of improved, Danish solid waste separation and treatment technology at a plant in a suburb of Hanoi. The technology enables the production of derived products, such as organic fertilizer, and is suitable for biogas......In business and socio-technical literature, partnerships are highlighted as an important tool for developing sustainable solutions to environmental challenges, such as the waste management systems of developing countries. In order to investigate the formation of North–South partnerships...... in this respect, the business development process of a Danish–Vietnamese partnership in the waste sector is analyzed in this paper. From a participant's perspective, a business development process is narrated, showing how innovation management in partnerships evolves: through socially and culturally influenced...

  2. Workplaces as Transformative Learning Spaces

    DEFF Research Database (Denmark)

    Maslo, Elina

    2010-01-01

    words: learning, lifelong learning, adult learning, workplace learning, transformative learning spaces During many years of research on lifelong foreign language learning with very different groups of learners, we found some criteria, which make learning process successful. Since then we tried to find......Abstract to the Vietnam Forum on Lifelong Learning: Building a Learning Society Hanoi, 7-8 December 2010 Network 2: Competence development as Workplace Learning Title of proposal: Workplaces as Transformative Learning Spaces Author: Elina Maslo, dr. paed., University of Latvia, elina@latnet.lv Key...... some other examples on “successful learning” from the formal, informal and non-formal learning environments, trying to prove those criteria. This presentation provides a view on to new examples on transformative learning spaces we discovered doing research on Workplace Learning in Latvia as a part...

  3. Problem-based learning (PBL) and public health: an initial exploration of perceptions of PBL in Vietnam.

    Science.gov (United States)

    Grisham, John W; Martiniuk, Alexandra L C; Negin, Joel; Wright, E P

    2015-03-01

    Worldwide interest in problem-based learning (PBL) has grown in past decades. This article aims to evaluate the perceived effectiveness, appropriateness, benefits, and challenges attributed to the use of PBL in public health education in Vietnam with a view to providing recommendations for curricular design and future policy. Teachers at 2 universities in Hanoi participated in group interviews, and students from these 2 universities completed Likert-style questionnaires. Students and teachers regarded PBL positively. However, there was consensus that hybrid models that used PBL alongside other methods are probably the most beneficial for public health education in Vietnam. Teachers discussed the educational and systematic advantages and difficulties associated with PBL. Themes arising from this analysis may be helpful in guiding future research-namely, regarding the application of PBL in low- and middle-income countries and in public health. Further exploration of the use of PBL hybrid models is discussed. © 2012 APJPH.

  4. Message about the « severe acute respiratory disease syndrome »

    CERN Multimedia

    2003-01-01

    If you are back from a journey in one of the zones pointed out by WHO concerned by the severe acute respiratory disease syndrome (SARS), it is necessary to monitor your health for at least ten days. This syndrome shows a high fever accompanied by cough or difficulty in breathing. If you become ill, you have to contact as quickly as possible the CERN medical service by dialling 73802 - 73186 during work hours or the Fire Brigade 74444 outside work hours. Tell this service about your recent travel to one of the regions where WHO has reported cases*. * For instant, the areas identified are the cities of Hanoi, Hong Kong, Singapore and the Province of Guangdong (South of China) and Toronto. The medical service recommends to avoid any trip in these world areas until further instruction. CERN Medical Service

  5. Health communication, information technology and the public's attitude toward periodic general health examinations.

    Science.gov (United States)

    Vuong, Quan-Hoang

    2016-01-01

    Background: Periodic general health examinations (GHEs) are gradually becoming more popular as they employ subclinical screenings, as a means of early detection. This study considers the effect of information technology (IT), health communications and the public's attitude towards GHEs in Vietnam. Methods: A total of 2,068 valid observations were obtained from a survey in Hanoi and its surrounding areas. Results: In total, 42.12% of participants stated that they were willing to use IT applications to recognise illness symptoms, and nearly 2/3 of them rated the healthcare quality at average level or below. Discussion: The data, which was processed by the BCL model, showed that IT applications (apps) reduce hesitation toward GHEs; however, older people seem to have less confidence in using these apps. Health communications and government's subsidy also increased the likelihood of people attending periodic GHEs. The probability of early check-ups where there is a cash subsidy could reach approximately 80%.

  6. Mobile, Flexible, and Adaptable

    DEFF Research Database (Denmark)

    Agergaard, Jytte; Thao, Thi Vu

    2011-01-01

    of the female porters demonstrate a particular way of adapting to the migration process. Also, it is emphasised how women's flexible practices are facilitated by women's own village-based networks. It is suggested that ‘in-betweenness’, which stands for the simultaneous and overlapping presence of urban......Industrialisation and urban growth are constitutive aspects of Vietnam's new economy and are important driving forces behind increasing rural-to-urban migration. Growth in informal sector employment is a significant aspect of this development, which has provided for both male and female migrants......, although they generally are engaged in different occupations. Based on a case study among porters at Hanoi's Long Bien Market, this paper examines rural-to-urban migrants' gendered migration practices. Two interrelated aspects of gendered migration practices are in focus: the role of migration networks...

  7. The Impact of Critical Thinking on Clinical Judgment During Simulation With Senior Nursing Students.

    Science.gov (United States)

    Cazzell, Mary; Anderson, Mindi

    2016-01-01

    The study examined the impact of critical thinking (CT) on clinical judgment (CJ) during a pediatric Objective Structured Clinical Evaluation (OSCE) with 160 pre-licensure nursing students. Educators are called to transform teaching strategies to develop CJ but confusion exists over definitions. A descriptive correlational design was used to examine demographics and Tower of Hanoi (TOH) and Health Science Reasoning Test (HSRT) scores. CJ was measured by scores on the Lasater Clinical Judgment Rubric (LCJR) from videotaped OSCEs. Participants were: 86 percent female, 42 percent Caucasian, median 23 years, with 49 percent having health care experience. Students averaged seven moves over minimum on the TOH. Average scores were: HSRT 25/38 and LCJR 31/44. Statistically significant predictors of CJ were gender, ethnicity, HSRT deduction, and analysis; 11 CT variables accounted for 17 percent of LCJR scores. Educators need to utilize/develop innovative teaching strategies addressing CJ predictors.

  8. Decision Making Based on Fuzzy Aggregation Operators for Medical Diagnosis from Dental X-ray images.

    Science.gov (United States)

    Ngan, Tran Thi; Tuan, Tran Manh; Son, Le Hoang; Minh, Nguyen Hai; Dey, Nilanjan

    2016-12-01

    Medical diagnosis is considered as an important step in dentistry treatment which assists clinicians to give their decision about diseases of a patient. It has been affirmed that the accuracy of medical diagnosis, which is much influenced by the clinicians' experience and knowledge, plays an important role to effective treatment therapies. In this paper, we propose a novel decision making method based on fuzzy aggregation operators for medical diagnosis from dental X-Ray images. It firstly divides a dental X-Ray image into some segments and identified equivalent diseases by a classification method called Affinity Propagation Clustering (APC+). Lastly, the most potential disease is found using fuzzy aggregation operators. The experimental validation on real dental datasets of Hanoi Medical University Hospital, Vietnam showed the superiority of the proposed method against the relevant ones in terms of accuracy.

  9. The mathematics of various entertaining subjects

    CERN Document Server

    Rosenhouse, Jason

    Volume 1 : The history of mathematics is filled with major breakthroughs resulting from solutions to recreational problems. Problems of interest to gamblers led to the modern theory of probability, for example, and surreal numbers were inspired by the game of Go. Yet even with such groundbreaking findings and a wealth of popular-level books exploring puzzles and brainteasers, research in recreational mathematics has often been neglected. The Mathematics of Various Entertaining Subjects brings together authors from a variety of specialties to present fascinating problems and solutions in recreational mathematics. Contributors to the book show how sophisticated mathematics can help construct mazes that look like famous people, how the analysis of crossword puzzles has much in common with understanding epidemics, and how the theory of electrical circuits is useful in understanding the classic Towers of Hanoi puzzle. The card game SET is related to the theory of error-correcting codes, and simple tic-tac-toe tak...

  10. Antibiotics in Wastewater of a Rural and an Urban Hospital before and after Wastewater Treatment, and the Relationship with Antibiotic Use—A One Year Study from Vietnam

    Directory of Open Access Journals (Sweden)

    La Thi Quynh Lien

    2016-06-01

    Full Text Available Hospital effluents represent an important source for the release of antibiotics and antibiotic resistant bacteria into the environment. This study aims to determine concentrations of various antibiotics in wastewater before and after wastewater treatment in a rural hospital (60 km from the center of Hanoi and in an urban hospital (in the center of Hanoi in Vietnam, and it aims to explore the relationship between antibiotic concentrations in wastewater before wastewater treatment and quantities of antibiotics used in the rural hospital, over a period of one year in 2013. Water samples were collected using continuous sampling for 24 h in the last week of every month. The data on quantities of antibiotics delivered to all inpatient wards were collected from the Pharmacy department in the rural hospital. Solid-phase extraction and high performance liquid chromatography-tandem mass spectrometry were used for chemical analysis. Significant concentrations of antibiotics were present in the wastewater both before and after wastewater treatment of both the rural and the urban hospital. Ciprofloxacin was detected at the highest concentrations in the rural hospital’s wastewater (before treatment: mean = 42.8 µg/L; after treatment: mean = 21.5 µg/L. Metronidazole was detected at the highest concentrations in the urban hospital’s wastewater (before treatment: mean = 36.5 µg/L; after treatment: mean = 14.8 µg/L. A significant correlation between antibiotic concentrations in wastewater before treatment and quantities of antibiotics used in the rural hospital was found for ciprofloxacin (r = 0.78; p = 0.01 and metronidazole (r = 0.99; p < 0.001.

  11. Cost and effectiveness comparison of two methods for screening potential blood donors for anaemia in Vietnam.

    Science.gov (United States)

    Tyrrell, A; Worrall, E; Que, T N; Bates, I

    2011-06-01

    To compare the cost and effectiveness of Copper Sulphate (CS) and HemoCue (HC) methods for screening blood donors for anaemia. Robust information from developing countries about cost and effectiveness of anaemia screening methods for blood donors is scarce. In such countries there are widespread shortages of blood, so the most cost-effective method should maximise blood supply without compromising donor safety. Economic data (e.g. staff time, equipment and buildings) were collected from direct observation of procedures and purchase data from Hanoi's Central Blood Bank administrative department. A framework for comparing the cost and effectiveness of anaemia screening methods was developed and a cost per effective (i.e. usable and accurate) test was generated for each method. Samples from 100 potential donors from the Hanoi Central Blood Bank (static) and 198 from two mobile units were tested. The mean probability of an ineffective anaemia test was 0·1 (0·05-0·2). The average cost of an HC test was $0·75 (static $0·61 and mobile $0·89) and a CS test was $0·31 (static $0·17 and mobile $0·45). The difference between static and mobile units was predominantly due to transport costs; the difference between the two methods was predominantly due to the HC microcuvettes. In this setting the CS yields greater value for money than the HC method for screening blood donors. The relative cost and effectiveness of CS and HC may be different in places with higher staff turnover, lower test accuracy, higher anaemia prevalence or lower workload than in Vietnam. © 2010 Liverpool School of Tropical Medicine. Transfusion Medicine © 2010 British Blood Transfusion Society.

  12. Intelligent System Design Using Hyper-Heuristics

    Directory of Open Access Journals (Sweden)

    Nelishia Pillay

    2015-07-01

    Full Text Available Determining the most appropriate search method or artificial intelligence technique to solve a problem is not always evident and usually requires implementation of the different approaches to ascertain this. In some instances a single approach may not be sufficient and hybridization of methods may be needed to find a solution. This process can be time consuming. The paper proposes the use of hyper-heuristics as a means of identifying which method or combination of approaches is needed to solve a problem. The research presented forms part of a larger initiative aimed at using hyper-heuristics to develop intelligent hybrid systems. As an initial step in this direction, this paper investigates this for classical artificial intelligence uninformed and informed search methods, namely depth first search, breadth first search, best first search, hill-climbing and the A* algorithm. The hyper-heuristic determines the search or combination of searches to use to solve the problem. An evolutionary algorithm hyper-heuristic is implemented for this purpose and its performance is evaluated in solving the 8-Puzzle, Towers of Hanoi and Blocks World problems. The hyper-heuristic employs a generational evolutionary algorithm which iteratively refines an initial population using tournament selection to select parents, which the mutation and crossover operators are applied to for regeneration. The hyper-heuristic was able to identify a search or combination of searches to produce solutions for the twenty 8-Puzzle, five Towers of Hanoi and five Blocks World problems. Furthermore, admissible solutions were produced for all problem instances.

  13. mHealth information for migrants: an e-health intervention for internal migrants in Vietnam.

    Science.gov (United States)

    Vu, Lan Thi Hoang; Nguyen, Ngan Thi Kim; Tran, Hanh Thi Duc; Muhajarine, Nazeem

    2016-05-14

    Socio-economic development in Vietnam has resulted in increased internal migration particularly among young women seeking employment opportunities in cities. Vietnamese female migrants who enter new environments often encounter the loss or neglect of their right to access sexual and reproductive health services. To address this, a mobile health (mHealth) intervention model was implemented over 12 months (2013-2014) in a factory in the Long Bien industrial zone of Hanoi, Vietnam. The intervention provided sexual and reproductive health services for female migrants through text messaging, information booklets accompanied maps, and free counseling via a hotline. To evaluate the impact of the intervention, pre- and post-intervention data were collected to measure changes in women's knowledge and practices related to sexual and reproductive health. Qualitative data in the form of personal interviews were also collected. The sample size for the baseline survey was 411 women, and for the post-intervention survey it was 482 women (the intervention involved an open cohort). The majority of women were unmarried and under the age of 25. Results indicate that there was high uptake of the intervention services and that most women found the services important and useful. In addition, there was evidence that the intervention (1) increased women's knowledge of sexual and reproductive health (e.g., proper use of condoms, identification of high-risk behaviors such as having unprotected sex), and (2) fostered improved practices related to sexual and reproductive health (e.g., increased gynecological check-ups and use of condoms). The study demonstrated the feasibility of implementing a multi-faceted intervention for migrant women working in an industrial zone in Hanoi, Vietnam as well as its successful uptake and some early positive effects. This can be used to inform future design and implementation of mHealth/eHealth intervention models for migrant and other vulnerable/hard to

  14. The incidence of primary antibiotic resistance of Helicobacter pylori in Vietnam

    Science.gov (United States)

    Binh, Tran Thanh; Shiota, Seiji; Nguyen, Lam Tung; Ho, Dung D Q; Hoang, Hai H; Ta, Long; Trinh, Dung T; Fujioka, Toshio; Yamaoka, Yoshio

    2012-01-01

    Goals To determine the susceptibility of Helicobacter pylori strains isolated from a Vietnamese population to 5 antibiotics. Background The incidence of antibiotic resistance in H. pylori infection is increasing worldwide and has become a leading cause for failure of treatment. Antibiotic susceptibility testing is very important to provide optimal regimens in a clinical setting. Study We isolated 103 H. pylori strains from the gastric mucosa of H. pylori-infected patients from 2 areas in Vietnam (Ho Chi Minh and Hanoi) in 2008. Epsilometer test was used to determine the minimum inhibitory concentrations of amoxicillin (AMX), clarithromycin (CLR), metronidazole (MNZ), levofloxacin (LVFX), and tetracycline (TC). Results Among the 103 strains, the resistance rates were 0% (AMX), 33% (CLR), 69.9% (MNZ), 18.4% (LVFX), and 5.8% (TC). The resistant strains showed a high-level of resistance (≥256 μg/mL) to CLR, 23.5% (8/34), and MNZ, 29.1% (21/72). The resistance rate for CLR was significantly higher in Ho Chi Minh than in Hanoi (49% vs. 18.5%, P = 0.001). Resistance to both CLR and MNZ was most commonly observed (24.3%). Two strains (1.9%) were resistant to 4 of the 5 antibiotics. No significant association was observed between antibiotic resistance rates and age, gender, or clinical outcomes of the patients. Conclusions High incidence of resistance to CLR and MNZ suggests that standard triple therapies may not be useful as first-line treatment in Vietnam. Alternative strategies such as bismuth-based quadruple therapies or sequential therapy may be more effective in Vietnam. PMID:23090037

  15. Prevalence and incidence of overweight and obesity among Vietnamese preschool children: a longitudinal cohort study.

    Science.gov (United States)

    Do, Loan Minh; Tran, Toan Khanh; Eriksson, Bo; Petzold, Max; Ascher, Henry

    2017-06-19

    A plateau in childhood overweight and obesity has been reported in some developed countries while in almost all developing countries this problem is on the rise. The aim of this paper is to describe the changes in prevalence of overweight and obesity within a cohort of preschool children followed for 3 years, and to estimate and compare the incidences in urban and rural children of Hanoi, Vietnam. A longitudinal study of a cohort of 2677 children aged 3 to 6 years old at the beginning of the study was conducted in urban DodaLab and rural FilaBavi, Hanoi, Vietnam. Overall, 2602 children, 1311 urban and 1291 rural, were followed for 3 years with identical measurements of weight and height in 2013, 2014 and 2016. Standard methods were used to estimate prevalence and incidence as well as confidence intervals. During the three-year follow-up, the overall estimated prevalence of overweight increased from 9.1% to 16.7%. For the urban children, the increase was considerably higher. The overall prevalence of obesity decreased from 6.4% to 4.5% with less decrease in the urban children. In the group of children who were overweight and obese at the start of the study, 41.4% and 30.7%, respectively, remained in the same state three years later. The incidence of overweight and obesity during the three years were 12.4% and 2.7%, respectively. Boys were more likely to develop obesity than girls. Already in preschool age, the prevalence of overweight is high and it continues to increase with age, especially in the urban area. Prevention and intervention programs need to start at early preschool age and actions in urban areas deserve priority.

  16. The relationship between sexual behavior and nonsexual risk behaviors among unmarried youth in three Asian cities.

    Science.gov (United States)

    Tu, Xiaowen; Lou, Chaohua; Gao, Ersheng; Li, Nan; Zabin, Laurie S

    2012-03-01

    Health risk behaviors in adolescents and youth, such as smoking, alcohol, drug use, violence, suicide, and unprotected sexual behavior, are issues of major public health concern. Addressing the relationship between sexual behavior and nonsexual risk behaviors will make a significant contribution to the design of effective intervention programs for this population of adolescents and unmarried youth. This cross-sectional study was conducted in three Asian cities with a common heritage of Confucian values: Hanoi, Shanghai, and Taipei. Data were collected in 2006 from 17,016 youth aged 15-24 years residing in both urban and rural districts of the three settings. The relationships between sexual behavior and seven nonsexual risk behaviors among unmarried adolescents were examined using χ(2) tests, logistic regression models, Cox regression models, and cluster analysis. Sexual behavior was associated with seven nonsexual risk behaviors, especially with smoking, drinking, drug use, and running away from home. In terms of the age at initiation of risk behaviors, smoking and drinking were usually initiated before sexual intercourse. Sexual behavior and nonsexual risk behaviors co-occurred in the high-risk group in all three cities. Youth having the highest risk of sexual behavior were more likely to have the highest risk of nearly all nonsexual risk behaviors, with the exception of fighting in Hanoi and gambling in Shanghai and Taipei. Sexual behavior among unmarried youth is correlated with nonsexual risk behaviors but with different patterns across the three settings. Interventions aimed at reducing unprotected sex generally focus only on the sexual behavior; however, considering the correlations found here between sexual and nonsexual risk behaviors, they should target multiple risk behaviors. Copyright © 2012 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  17. Social and economic burden of patients with influenza-like illness and clinically diagnosed flu treated at various health facilities in Vietnam

    Directory of Open Access Journals (Sweden)

    Quang Vo T

    2017-07-01

    Full Text Available Trung Quang Vo,1,2 Usa Chaikledkaew,1,3 Minh Van Hoang,4 Arthorn Riewpaiboon1 1Department of Pharmacy, Division of Social and Administrative Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand; 2Department of Pharmacy Administration, Faculty of Pharmacy, University of Medicine and Pharmacy, Ho Chi Minh City, Vietnam; 3Health Intervention and Technology Assessment Program (HITAP, Ministry of Public Health, Nonthaburi, Thailand; 4Hanoi School of Public Health, Hanoi, Vietnam Abstract: Influenza is a malady related to the human respiratory system, and its influenza-like illness (ILI can cause an economic and social burden, especially among children and the elderly. This study was conducted to estimate the cost of illness based on a social perspective of ILI cases. A prospective study was conducted between February and March of 2016 in pharmacies, private clinics at Khanh Hoa, Lam Dong, Tay Ninh, Dong Nai Province, and Ho Chi Minh City, and Hospital of Tropical Diseases. Demographic and clinical information were collected by face-to-face interview. Direct costs (e.g., diagnosis and therapeutics and indirect costs (e.g., cost of day loss are included as treatment costs. The average cost of treatment associated with ILI was US$ 88.09 per case for all age groups; direct non-medical cost was higher compared to direct medical cost: 39.5% in pharmacies, 71.1% in clinics, and 64.2% in hospital. The indirect cost was US$27.49 per episode. The average total cost for children below 14 years old was much higher than that for the other age groups. The cost of illness of ILI was, therefore, the reason for the economic burden of influenza patients and their families. This study provides a database for future research and programs, and policies that can be adopted for influenza or ILI in Vietnam. Keywords: influenza, influenza-like illness, economic burden, cost of illness, pharmacy, clinic, hospital, Vietnam

  18. Airborne volatile organic compounds in urban and industrial locations in four developing countries

    Science.gov (United States)

    Do, Duc Hoai; Walgraeve, Christophe; Amare, Abebech Nuguse; Barai, Krishna Rani; Parao, Amelia Estigoy; Demeestere, Kristof; van Langenhove, Herman

    2015-10-01

    Volatile organic compounds (VOCs) represent an important class of air pollutants, however their concentration levels in developing countries have scarcely been reported in literature. Therefore, concentration levels of 60 VOCs were determined at 27 urban and industrial locations in seven different cities in Ethiopia, Vietnam, the Philippines and Bangladesh between 2011 and 2014. Active sampling using Tenax TA as a sorbent was employed followed by TD-GC-MS analysis using internal standard calibration. It was found that TVOCs concentration levels in Dhaka, Bangladesh (arithmetic mean: 343 and 399 μg/m3 for urban and industrial campaign, respectively) were more than 10 times higher when compared to TVOCs levels observed in Mekelle, Ethiopia. ∑BTEX concentration at street sites ranges from 36 μg/m3 in Mekelle, to 100 and 250 μg/m3 in Hanoi, Vietnam and Dhaka, Bangladesh, respectively. The indoor to outdoor concentration ratios were found to be dependent on the country, type of environment, VOC compound and outdoor reference location. The highest Ozone Formation Potential (OFP, 2150 μg/m3), calculated from the same set of seven aromatic VOCs, was obtained at the street site in Dhaka. This OFP value is a factor three and four times higher than the OFP value observed at the street sites in Hanoi, and Manila, respectively. Finally, the Cumulative Cancer Risk (CCR) calculated for four carcinogenic VOCs ranged from 97 × 10-6 in urban Mekelle to 299 × 10-6 in urban Dhaka. This work provides for the first time comparisons of CCR in urban and industrial environments in the selected developing countries.

  19. Stress faced by gifted Vietnamese students: what might contribute to it?

    Directory of Open Access Journals (Sweden)

    Minh Hang Thi Nguyen

    2015-11-01

    Full Text Available Background Gifted students might have to face an abundance of stress. Nevertheless, very little evidence in Vietnam indicates how much stress those students are experiencing and what might predict it. This study aims to examine the stress level in students of the High School for Gifted Students in Hanoi and factors that might contribute to the stress. Participants and procedure This is a cross sectional study with the participation of 150 students from the High School for Gifted Students, Hanoi. Data were collected from March to April 2015. The first measure was the “Stress Level Test”, which was adapted to the Vietnamese culture to measure academic stress in students. The second measure examined factors contributing to stress: 1 social life, 2 family, 3 school work, 4 personal relationships, 5 well-being, 6 adapting skills. Results The results showed that 74% of students were experiencing mild to medium stress, which was found to be higher in girls and in students who lived away from home. The six predicting factors significantly contribute 17.30% to students’ stress experience, of which school work (p = .001 and students’ well-being (p = .011 can individually predict stress. These outcomes suggested that more attention should be focused on this specific population and more actions need to be taken to help them perform better at school. Conclusions Students of the High School for Gifted Students definitely experienced a considerable amount of stress which was related to school pressure and their well-being. For them to have a better high school life, more recreational and leisure time activities outside the classroom need to take place. In addition, more approachable and functional advisors and counseling personnel would be an ideal solution to this problem.

  20. Study of the clinical and functional characteristics of asthmatic children with obstructive sleep apnea

    Directory of Open Access Journals (Sweden)

    Nguyen-Hoang Y

    2017-10-01

    Full Text Available Yen Nguyen-Hoang,1 Thuy Nguyen-Thi-Dieu,2 Sy Duong-Quy3–5 1Department of Pediatrics, Phu Tho General Hospital, Phu Tho Province, 2Department of Pediatrics, Hanoi Medical University, Hanoi, 3Biomedical Research Center, Lam Dong Medical College, Dalat, Vietnam; 4Department of Physiology and Lung Function Testing, Cochin Hospital, Paris Descartes University, Paris, France; 5Division of Asthma and Immuno-Allergology, Hershey Medical Center, Penn State Medical College, Hershey, PA, USA Background and objective: The obstructive sleep apnea (OSA is a common respiratory disorder in children, especially those at preschool and school ages. This study aimed to describe the characteristics of asthmatic children with OSA and the symptoms for a high risk of OSA. Subjects and methods: It was a prospective and descriptive study. The data of asthmatic children including medical history, clinical examination, blood tests, spirometry, exhaled nitric oxide (NO, and respiratory polygraphy were registered for analyses. Results: Eighty-five asthmatic children with a mean age of 9.5 ± 2.1 years were included. The prevalence of OSA was 65.9% (56/85 in study subjects. The prevalence of severe OSA in children with moderate asthma was significantly higher than intermittent and mild asthma. The percentage of asthmatic children with OSA who had snoring, sleep disturbance, and nocturnal sweats was significantly higher than that of asthmatic children without OSA (48.2% vs 17.2%, 71.4% vs 27.5%, and 55.1% vs 31.0%, respectively. The presence of allergic rhinitis and snoring was associated significantly with a high probability for the presence of OSA. Conclusion: Children with asthma have a risk of OSA. Asthmatic children with suggested symptoms such as snoring or waking up at night should be screened for OSA. Keywords: asthma, OSA, snoring, allergic rhinitis

  1. Response of first attack of inflammatory bowel disease requiring hospital admission to steroid therapy Respuesta al tratamiento esteroideo del primer brote de enfermedad inflamatoria intestinal que requiere ingreso hospitalario

    Directory of Open Access Journals (Sweden)

    M. Abu-Suboh Abadía

    2004-08-01

    Full Text Available Introduction: corticoid administration is the usual treatment of Crohn' disease (CD and ulcerative colitis (UC attacks. How-ever, information available on response rates and their predictive factors is scarce. Objective: to establish response to steroidal treatment in an homogeneous group of patients with CD or UC during their first admission to hospital. Methods: restrospective analysis of 86 patients who received systemic steroidal treatment for a severe flare-up during their first hospital admission between 1995 and 2000. Patients were treated per protocol with fluid therapy, absolute diet, IV 6-methyl-prednisolone 1 mg/kg/day, and enoxaparin at prophylactic doses. Clinical response at 30 days was considered good in case of complete remission, and poor in case of partial or absent remission. Univariate and multivariate analyses according to non-parametric statistics were performed for sociodemographic and biologic variables. Results: 45 patients with CD and 41 with UC were included. Good response rates were 64.4% for CD and 60.9% for UC. The univariate analysis showed that patients with good response have shorter evolution times and fewer previous flare-ups (p Introducción: la administración de corticoides constituye el tratamiento habitual de los brotes de enfermedad de Crohn (EC y colitis ulcerosa (CU. Sin embargo, existe poca información sobre las tasas de respuesta y los factores que puedan predecirla. Objetivo: determinar la respuesta al tratamiento esteroideo en un grupo homogéneo de pacientes de EC y CU que ingresan por primera vez en el hospital. Métodos: análisis retrospectivo de 86 pacientes que en su primer ingreso hospitalario recibieron tratamiento esteroideo sistémico por brote grave de EC o CU entre 1995 y 2000. Fueron tratados de forma protocolizada con sueroterapia, dieta absoluta, 6-metil-prednisolona 1 mg/kg/día IV y enoxaparina a dosis profilácticas. Se ha considerado la respuesta clínica a los 30 días como

  2. Variation among species in the endocrine control of mammary growth and function: the roles of prolactin, growth hormone, and placental lactogen.

    Science.gov (United States)

    Forsyth, I A

    1986-03-01

    Prolactin, growth hormone, and placental lactogen form a family of structurally related hormones, which may have evolved from a common ancestral peptide. Prolactin and growth hormone are present in all mammals, but the biological activity associated with placental lactogen has been detected in only some groups. Attempts to detect placental lactogen using bioassay and radioreceptor assay are reported and have been unsuccessful in an insectivore (the shrew), a bat, an edentate (the armadillo), a lagomorph (the rabbit), several carnivores (dog, cat, ferret), perissodactyls (horse, zebra, rhino), and, within the artiodactyls, pigs. Placental lactogenic activity has been detected in primates (chimpanzee, orangutan), rodents (voles, Pinon mouse, guinea-pig, mara), and in numerous artiodactyls (llama, giraffe, several species of deer, antelope, gnu, gazelle, musk ox, cape buffalo, Barbary sheep, several sheep of the genus Ovis, goat, and cow). These results confirm and extend the work of others and are discussed in relation to the evolution of these hormones. In synergism with steroid and thyroid hormones, protein hormones of the prolactin and growth hormone family play a crucial role in stimulating the development of the mammary gland, the differentiation and function of mammary cells to secrete milk, and in the systemic adjustments in maternal metabolism in pregnancy and lactation. Studies in vitro have shown that mammary tissues from several species synthesize milk components in response to insulin plus adrenal corticoid plus prolactin. However, there are also species differences in minimal hormonal requirements for lactogenesis. In vivo, for example, rabbits will initiate or sustain lactation in response to prolactin alone, whereas sheep and goats require prolactin plus growth hormone plus adrenal corticoid plus thyroid hormone. Measurement of hormone concentrations in the plasma of pregnant animals shows considerable differences among species in the pattern of

  3. Nefropatía por Inmunoglobulina A: Guía de práctica clínica

    Directory of Open Access Journals (Sweden)

    Alicia Fayad

    2011-05-01

    Full Text Available La nefropatía por Inmunoglobulina A (N.IgA es la causa más frecuente de enfermedad glomerular a nivel mundial, 15-50% de los pacientes presentan pérdida progresiva de la función renal en 10-20 años; el resto remisión clínica o hematuria/ proteinuria persistente. Su tratamiento óptimo es incierto. Nuestro objetivo fue desarrollar recomendaciones basadas en la evidencia a través de búsqueda en bases de datos Medline, Embase, Lilacs, Cochrane Trials Register. Los investigadores analizaron la calidad de los estudios independientemente, usando la Cochrane Renal Group checklist: aleatorización, carácter ciego, intención de tratar y pérdidas en el seguimiento. La evidencia se clasificó en niveles y la recomendación en grados, según el Centre for Evidence-Based Medicine, Oxford, con dos enfoques principales: Terapia inmunosupresora (corticoides, citostáticos, ciclosporina A y micofenolato mofetilo: Nivel I a, grado A. Terapia combinada con inmunosupresores en adultos: Nivel II b, grado B. Corticoides más ciclofosfamida o azatioprina en niños: Nivel II b, grado C. Ciclosporina y micofenolato-mofetilo: Nivel II b, grado B. Terapia no inmunosupresora: inhibidores del sistema renina-angiotensina (IEAC y/o bloqueantes del receptor de angiotensina II (BRAII, aceite de pescado, estatinas, antiplaquetarios y tonsilectomía: Nivel I a, grado A. Niños: IECA y BRAII con monitoreo de función renal y de nivel sérico de potasio: Nivel I b, grado B. En nefropatía progresiva, antiplaquetarios como tratamiento coadyuvante: Nivel I, grado C. Aceite de pescado como soporte adicionado de BRAII e IECA en pacientes con lesiones histológicas leves y baja reducción de la filtración glomerular: Nivel II b, grado B (no en niños. No hay evidencias para recomendar estatinas en niños; en mayores de 5 años con síndrome nefrótico e hipercolesterolemia usar sólo con monitoreo de fosfocreatin-kinasa sérica. No hay evidencias para recomendar la

  4. Notalgia parestésica: relato de caso

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    José Otávio Alquezar Gozzano

    2016-10-01

    Full Text Available Introdução: Notalgia parestésica (NP é uma condição neurocutânea, caracterizada por crises pruriginosas, hiperpigmentação e neuropatia sensorial. Apesar de pouco descrita em literatura, a doença é mais frequente do que se imagina, sendo subdiagnosticada em muitos casos. NP pode afetar qualquer idade e sexo, mas acomete principalmente pessoas de média idade e mulheres. Sua etiologia inclui alterações degenerativas vertebrais, trauma vertebral e predisposição genética. NP envolve o trajeto anatômico dos nervos espinhais e está relacionada com o comprometimento de neuropeptídios, dando origem a marcapassos neurais ectópicos, responsáveis pela clínica da NP. O diagnóstico é clínico, a partir da identificação de máculas hiperpigmentadas unilaterais em zona escapular, sem eritema ou descamação, com piora ao estresse. Deve-se diferenciar de líquen simples, amiloidose macular e hanseníase. Na anatomopatologia observa-se acantose focal e queratinócitos necróticos; a derme papilar mostra depósito de substância amiloide. Com sintomas leves o tratamento medicamentoso nem sempre é necessário, se mais severa utiliza-se capsaicina tópica, gabapentina, oxicarba-mazepina, corticoides e toxina botulínica. Objetivo: Relatar caso de NP. Material e métodos: Paciente atendida ambulatorialmente com revisão de literatura. Relato de Caso: Feminina, 50 anos, com queixa de mancha em dorso há 2 anos; refere dor na coluna torácica. Ao exame: presença de mácula hipercrômica. Hipótese diagnóstica: NP. Foi prescrito corticoide tópico para alívio de sintomas. Conclusão: Por tratar-se de uma doença subdiagnosticada, o conhecimento médico da clínica de NP é fundamental para o diagnóstico precoce, permitindo a escolha do tratamento específico, o que melhora a evolução dos pacientes e evita o uso de fármacos ineficazes.

  5. Recomendaciones para la prevención, diagnóstico y tratamiento de LA EPOC en la Argentina

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    Juan Carlos Figueroa Casas

    2012-08-01

    Full Text Available La enfermedad pulmonar obstructiva crónica (EPOC está aumentando marcadamente su morbimortalidad, costos e indicadores epidemiológicos. Por ello la Asociación Argentina de Medicina Respiratoria (AAMR convocó a un grupo de especialistas para actualizar conocimientos básicos y efectuar recomendaciones para su diagnóstico, prevención y tratamiento. Se revisan definición, avances en fisiopatología, presentación clínica, diagnóstico por imágenes y evaluación funcional. Se enfatiza su diagnóstico temprano mediante exploración funcional -esencialmente espirometría- y la prevención a través de la cesación del tabaquismo. Se describen estrategias para dejar de fumar, tratamiento farmacológico y no farmacológico. La administración de broncodilatadores, preferentemente de acción prolongada, es la primera opción de tratamiento farmacológico. Los corticoides inhalados se indican en combinación con los broncodilatadores en pacientes con obstrucción al flujo aéreo persistente asociada con exacerbaciones frecuentes, si bien se requieren estudios que confirmen su relación costo/beneficio. La vacuna antigripal es recomendada en todos los pacientes. Con respecto a las intervenciones no farmacológicas, la cirugía del enfisema solo se recomienda en circunstancias especiales. La rehabilitación respiratoria es una herramienta útil en pacientes con limitación en la actividad física habitual. La oxígenoterapia crónica domiciliaria mejora la supervivencia en pacientes con hipoxemia crónica grave. La ventilación no invasiva domiciliaria fuera de las exacerbaciones, tiene indicaciones en pacientes seleccionados. Las exacerbaciones agudas deben tratarse con broncodilatadores, oxígeno, corticoides, antibióticos y, bajo ciertas circunstancias, asistencia respiratoria mecánica tanto no invasiva como invasiva. El papel de la educación pública, del paciente y su familia, es considerada esencial en la prevención y tratamiento.

  6. Estrategia de atención de niños hospitalizados por infecciones respiratorias agudas bajas

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    Ana M Ferrari

    2002-06-01

    Full Text Available OBJETIVO: Mejorar la calidad de la atención hospitalaria de los niños con infecciones respiratorias agudas bajas, aumentar los conocimientos sobre esa patología y mejorar la eficiencia en el uso de los recursos asistenciales, por medio de una estrategia que se denominó Plan de Invierno.MÉTODOS: La estrategia se basó en la utilización de protocolos de diagnóstico y tratamiento, internación por cuidados progresivos y por enfermedad, adecuación de los recursos asistenciales y creación de un sistema de registro permanente, informatizado. Se incorporó la investigación sistemática de la etiología viral para racionalizar el uso de la medicación y reducir las infecciones intrahospitalarias. RESULTADOS: Durante la aplicación del Plan (19/V-19/IX/99 ingresaron 3.317 niños; 1.347 (40.61% presentaban infecciones respiratorias agudas bajas. Se captaron 1.096 (81%, de los cuales 71% eran menores de un año. Predominaron las infecciones respiratorias virales (68%. Los criterios de ingreso fueron saturación de oxígeno <95%, polipnea, tiraje o derrame pleural en el 92.4% de los niños. La magnitud de la demanda impidió que las pautas de aislamiento individual o en grupo se cumplieran en todos los casos. El uso de la medicación se ajustó a lo recomendado en un elevado porcentaje: no recibieron antibióticos 73% de las bronquiolitis ni 72% de las neumonías virales, y 96% de las neumonias bacterianas los recibieron según pauta; se redujo el uso de broncodilatadores y de corticoides. El gasto en medicamentos disminuyó fundamentalmente en el grupo de los corticoides y tuvo el mayor impacto en el costo por día/cama de antibióticos. CONCLUSIONES: Disminuir la morbimortalidad por infecciones respiratorias agudas bajas requiere continuar mejorando la calidad de la atención hospitalaria y fortalecer los programas de promoción de salud y de control de las enfermedades prevalentes, en el primer nivel de atención.

  7. Estrategia de atención de niños hospitalizados por infecciones respiratorias agudas bajas

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    Ferrari Ana M

    2002-01-01

    Full Text Available OBJETIVO: Mejorar la calidad de la atención hospitalaria de los niños con infecciones respiratorias agudas bajas, aumentar los conocimientos sobre esa patología y mejorar la eficiencia en el uso de los recursos asistenciales, por medio de una estrategia que se denominó Plan de Invierno.MÉTODOS: La estrategia se basó en la utilización de protocolos de diagnóstico y tratamiento, internación por cuidados progresivos y por enfermedad, adecuación de los recursos asistenciales y creación de un sistema de registro permanente, informatizado. Se incorporó la investigación sistemática de la etiología viral para racionalizar el uso de la medicación y reducir las infecciones intrahospitalarias. RESULTADOS: Durante la aplicación del Plan (19/V-19/IX/99 ingresaron 3.317 niños; 1.347 (40.61% presentaban infecciones respiratorias agudas bajas. Se captaron 1.096 (81%, de los cuales 71% eran menores de un año. Predominaron las infecciones respiratorias virales (68%. Los criterios de ingreso fueron saturación de oxígeno <95%, polipnea, tiraje o derrame pleural en el 92.4% de los niños. La magnitud de la demanda impidió que las pautas de aislamiento individual o en grupo se cumplieran en todos los casos. El uso de la medicación se ajustó a lo recomendado en un elevado porcentaje: no recibieron antibióticos 73% de las bronquiolitis ni 72% de las neumonías virales, y 96% de las neumonias bacterianas los recibieron según pauta; se redujo el uso de broncodilatadores y de corticoides. El gasto en medicamentos disminuyó fundamentalmente en el grupo de los corticoides y tuvo el mayor impacto en el costo por día/cama de antibióticos. CONCLUSIONES: Disminuir la morbimortalidad por infecciones respiratorias agudas bajas requiere continuar mejorando la calidad de la atención hospitalaria y fortalecer los programas de promoción de salud y de control de las enfermedades prevalentes, en el primer nivel de atención.

  8. Prevalencia de los factores de riesgo de fractura por fragilidad en varones de 40 a 90 años de una zona básica de salud rural

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    Rafael Gómez Navarro

    2011-01-01

    Full Text Available Fundamento: La osteoporosis, y como consecuencia de ella las fracturas por fragilidad, se han convertido en los últimos años en un importante problema de salud pública en los países desarrollados. Aunque es bien conocida su epidemiología y factores de riesgo en la mujer postmenopáusica son escasos los trabajos centrados en analizar esta patología en los hombres. El objetivo es determinar la prevalencia de los factores de riesgo de fractura por fragilidad en los varones y calcular su riesgo absoluto de fractura osteoporótica mayor y de fractura de cadera. Métodos: Estudio descriptivo transversal realizado en una zona de salud rural. La población de estudio fueron los varones de entre 40 y 90 años. No se contemplaron causas de exclusión. Se realizó entrevista personal recogiendo los siguientes datos: edad, peso, talla, índice de masa corporal (IMC, antecedente de fractura previa, antecedente de fractura de cadera en progenitores, habito tabáquico, consumo de corticoides, antecedente de artritis reumatoide, osteoporosis secundaria, consumo de alcohol y densidad mineral ósea (DMO. Con estos datos se calculó el riesgo absoluto de fractura y el riesgo de fractura de cadera mediante la aplicación de la herramienta FRAX®. Resultados: Se estudió a 431 hombres. Media de edad 65,8 ± 13,9 años e IMC de 28,4 ± 4,3 Kg/m². A ninguno se le había determinado DMO. Prevalencia de los factores de riesgo: fractura previa 3,7%; progenitores con fractura de cadera 10,4%; fumadores 21,1%; corticoides 2,8%; artritis reumatoide 0,9%; osteoporosis secundaria 2,3%; alcohol 30,9%. Riesgo absoluto de fractura del 3,7 ± 3,1 IC al 95% (3,43-4,02 y riesgo de fractura de cadera del 1,7 ± 2,5 IC al 95% (1,51-1,98. Conclusiones: Especialmente importante en el varón sería supresión del alcohol y del tabaco.

  9. Ofidismo en la provincia de Chanchamayo, Junín: revisión de 170 casos consecutivos en el Hospital de Apoyo de La Merced

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    Miguel Villanueva Forero

    2004-04-01

    Full Text Available Objetivo: Describir las características clínico-epidemiológicas del ofidismo en la provincia de Chanchamayo, Junín, Perú. Materiales y métodos: Se revisaron todas las historias clínicas de pacientes con diagnóstico de ofidismo en el "Hospital de Apoyo de La Merced" (HALM, Junín, Perú entre enero de 1998 y diciembre del 2000. Se recogieron datos de demográficos y clínico-epidemiológicos. Resultados: Las historias clínicas revisadas fueron 195, de estas, 170 fueron incluidas en el análisis. La media edad fue 26.2 años (rango: 1-76 años. La mayoría (62.4% era de sexo masculino. El 43.5% provenía del distrito de La Merced. Los casos de ofidismo ocurrieron con mayor frecuencia (67% durante los meses de lluvia (de diciembre a mayo. La localización más frecuente de la mordedura fue en los miembros inferiores (67.7%. El tiempo entre el accidente y la atención médica fue en promedio de 5 hrs. 43 min. (± 5 hrs. 56 min.. El animal agresor se identificó en 37.6% de las veces, siendo el más frecuente el Bothrops atrox (36.5%. Los síntomas más comunes que acompañaron el cuadro clínico fueron dolor, edema, eritema (80%. La mayoría (78.3% recibió suero antiofídico, de estos, 18.8% presentaron reacciones anafilactoides o urticariformes luego de la administración. La complicación más frecuente fue celulitis, presentándose mas comúnmente en pacientes que recibieron corticoides por más de 5 días (p=0.024. Ningún paciente falleció. Conclusiones: La mayoría de accidentes ofídicos en esta región ocurren en el ámbito rural. La utilización de corticoides por más de 5 días se asoció con una mayor frecuencia de celulitis. Las reacciones de hipersensibilidad hacia el suero antiofídico no son raras, siendo recomendable realizar la prueba intradérmica antes de su administración. (Rev Med Hered 2004; 15: 82-87.

  10. Análisis retrospectivo de 23 años de necrólisis epidérmica tóxica en la Unidad de Quemados de Alicante, España

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    F.I. Castillo-Muñoz

    2014-09-01

    Full Text Available El Síndrome de Lyell o Necrólisis Epidérmica Tóxica (NET se encuadra dentro del espectro de reacciones cutáneas adversas graves y se caracteriza por presentar una baja incidencia pero una elevada mortalidad. La mayoría de los casos de NET se relacionan con una reacción medicamentosa idiosincrática. El objetivo de este trabajo es reflejar la experiencia clínica con esta entidad en la Unidad de Quemados del Hospital General Universitario de Alicante, España, durante los últimos 23 años. Realizamos un estudio retrospectivo recogiendo los datos epidemiológicos, agentes causales probables, pruebas complementarias, patologías concomitantes, tratamiento y evolución clínica. En total recogimos 16 pacientes con una media de edad de 53,19 años, 68,75% mujeres y 31,25% varones. Los antibióticos fueron los fármacos más comúnmente implicados (31,25%, seguidos de los AINES (25%. Durante el ingreso hospitalario, el 43,75% de los pacientes recibió corticoides sistémicos, el 37,5% exclusivamente tratamiento de soporte y el 25% inmunoglobulinas intravenosas. El 56,25% sufrió algún tipo de secuela, siendo la afectación ocular la más frecuente (18,75%. Calculamos el SCORTEN (Severity of illness score for toxic epidermal necrolisys para todos los pacientes en las primeras 24 horas de ingreso, siendo la suma de las probabilidades predichas de morir por NET de un 32%, cifra superior a los datos reales (mortalidad del 25%. La utilización de corticoides sistémicos sigue siendo controvertida, apareciendo en nuestro estudio un mayor número de infecciones y una mayor mortalidad asociada a dicho tratamiento. La retirada inmediata del fármaco sospechoso, el ingreso precoz en una Unidad de Quemados o de Cuidados Intensivos, el tratamiento de soporte y la reposición hidroelectrolítica, siguen siendo medidas cruciales y de primera línea en el tratamiento de estos pacientes. A pesar de que están descritos diferentes tipos de tratamiento

  11. Adesão dos profissionais de saúde a práticas pré- e neonatais de redução da mortalidade neonatal: 2004 versus 2012

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    Renata Jaccottet Freitas

    Full Text Available RESUMO: Objetivo: Avaliar a adesão dos profissionais de saúde a práticas de assistência pré-natal e neonatal para reduzir a mortalidade neonatal. Métodos: Estudo não controlado, do tipo antes-e-depois, que avaliou a mudança ocorrida entre os anos 2004 e 2012, após as intervenções propostas pelo Comitê Municipal de Investigação de Óbitos Infantis, Fetais e de Morte Materna (COMAI na cidade de Pelotas, Rio Grande do Sul, na frequência de indicadores de processo de melhoria na assistência perinatal. Foram estudados 254 pacientes no ano de 2004 e 259 no ano de 2012. Resultados: Foi observado aumento de 65% na frequência do uso de corticoide pré-natal entre gestantes em trabalho de parto prematuro com idade gestacional ≤ 34 semanas (frequência de uso de 38,0 e 62,8% em 2004 e 2012, respectivamente; p < 0,001 e de 35% no uso de surfactante entre recém-nascidos ≤ 34 semanas de idade gestacional (41,3 e 55,6% em 2004 e 2012, respectivamente; p = 0,025, assim como uma redução de 16% na presença de hipotermia (70,8 e 59,4% em 2004 e 2012, respectivamente; p = 0,009 na admissão à unidade de terapia intensiva neonatal. Conclusão: Houve melhora em algumas das práticas de assistência pré-natal e neonatal. Ao final do período estudado, as frequências de uso de corticoide pré-natal e de surfactante foram menores do que as relatadas internacionalmente. No mesmo sentido, a frequência de hipotermia na admissão à unidade de terapia intensiva neonatal foi maior do que a observada em países desenvolvidos.

  12. Trends in Infant mortality rate and mortality for neonates born at less than 32 weeks and with very low birth weight Tendencia de la mortalidad infantil y de neonatos menores de 32 semanas y de muy bajo peso Tendência da mortalidade infantil e dos neonatos menores de 32 semanas e de muito baixo peso

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    René Mauricio Barría-Pailaquilén

    2011-08-01

    Full Text Available The aim of the study was to assess the trend of the infant mortality rate between 1990-2004 and the neonatal mortality between 2000-2005 in infants born at less than 32 weeks of gestational age or with very low birth-weight. Based on secondary data, infant mortality rate and by its component for Valdivia city were compared with national indicators. Mortality at Para evaluar la tendencia de la mortalidad infantil entre 1990-2004 y la mortalidad de prematuros menores de 32 semanas de edad de gestación y niños de muy bajo peso al nacer, entre 2000-2005, se compararon los datos secundarios globales por componentes del Servicio de Salud Valdivia con los totales del país, en Chile. Se calculó la mortalidad específica, por mil nacidos vivos, para los Para avaliar a tendência da mortalidade infantil, entre 1990 e 2004, a mortalidade de prematuros <32 semanas de idade gestacional e crianças de muito baixo peso ao nascer, entre 2000 e 2005, compararam-se dados secundários globais e por componentes do Serviço de Saúde Valdivia, e do total do país (Chile. Calculou-se a mortalidade específica em <32 semanas e <1.500g, por mil nascidos vivos, estabelecendo causas de óbito e avaliando sua relação com intervenções específicas, como uso de surfactante e corticoides pré-natais. A mortalidade infantil deteve sua queda a partir do ano 2000, com referência à década precedente, e a brecha que existia, entre os valores nacionais e locais antes de 2000, reduziu drasticamente. A mortalidade em <32 semanas e <1.500g variou entre 88 e 200‰ nascidos vivos, destacando a síndrome da angústia respiratória como principal causa de morte. O uso de corticoides e surfactante coincidiu com reduções da mortalidade.

  13. Health, treatment and health care resources consumption profile among Spanish adults with diabetes and chronic obstructive pulmonary disease.

    Science.gov (United States)

    Jimenez-Garcia, Rodrigo; de Miguel-Díez, Javier; Rejas-Gutierrez, Javier; Martín-Centeno, Antonio; Gobartt-Vázquez, Elena; Hernandez-Barrera, Valentin; Gil de Miguel, Angel; Carrasco-Garrido, Pilar

    2009-08-01

    To describe the health, treatment and health care resources consumption profile among Spanish adults with diabetes and chronic obstructive pulmonary disease (COPD), and compare it with that of non-diabetic COPD patients. An observational and descriptive epidemiological study (EPIDEPOC study). The study included patients with stable COPD and aged > or =40 years, evaluated in primary care. Data were collected relating to sociodemographic variables, health profile, quality of life (SF-12), treatment and health care resources consumption. The results corresponding to diabetic and non-diabetic patients were compared. A total of 10,711 patients (75.6% males) with COPD were evaluated. The prevalence of diabetes was 16.9%. The diabetic patients were significantly older, with a larger percentage of women, and a lesser educational level compared with the non-diabetic patients. In addition, the diabetics were more sedentary, smoked less, and presented a higher percentage of obesity (33.6% versus 19.7%) than the non-diabetic patients. The severity of airways obstruction was greater among the diabetics than in the non-diabetic patients (54.57+/-13.37% versus 57.92+/-13.39%, respectively, pdiabetics showed a greater frequency of arterial hypertension, hypercholesterolemia, heart disease, depression and anxiety. Both the physical and the mental component as measured by the SF-12 yielded significantly poorer results among the diabetics. On the other hand, the diabetic subjects showed a higher consumption of drugs for COPD. In addition, they consumed significantly more health care (and thus economical) resources than the non-diabetic patients. The results of the multivariate logistic regression analysis showed that the variables that were independently associated to COPD among diabetic patients were: higher age, higher BMI, concomitant chronic heart disease, use of inhaled corticoids, SF-12 mental component, SF-12 physical component and total cost of COPD. The presence of diabetes

  14. Eritema multiforme mayor desencadenado por antimicrobianos Big multiform erythema triggered by antimicrobials

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    Ronaldo de Carvalho Raimundo

    2010-03-01

    Full Text Available El eritema multiforme, aparece como una enfermedad sistémica con la participación de la piel y las membranas mucosas en relación con varios factores como las infecciones bacterianas o virales, y en particular la administración de drogas, analgésicos y antibióticos en general. Se presenta un paciente masculino de 29 años de edad con eritema multiforme mayor desencadenado por antimicrobianos con la aparición de lesiones vesiculares-bulloso-ulcerosas en las regiones de los labios, encías, la lengua y la mucosa genital en tratamiento de una infección del tracto urinario con norfloxacino 400 mg por una semana. Fue realizado un tratamiento de soporte con el uso de colutorios para la higienización bucal y pomada a base de corticoide para protección de las úlceras, antihistamínicos y orientación nutricional de dieta líquida hipercalórica e hiperproteica. Este síndrome está caracterizado como un proceso eruptivo buloso agudo que compromete la calidad de vida del paciente y no hay pruebas de laboratorio específicas por lo que su diagnóstico debe estar basado en la revisión minuciosa de la anamnesis y en los hallazgos clínicos.The multiform erythema appears as a systemic disease where skin and the mucous membranes have participation in relation to some factors such as bacterial or viral infections and in particular the drugs administration, analgesics and antibiotics in general. The aim of present paper was the presentation of case of big multiform erythema triggering by antimicrobials. Authors present the case of a male patient aged 29 with appearance of ulcerous bullous-vesicular lesions in lips, gums, tongue and genital mucosa under treatment with 400 mg norfloxacin due to urinary tract infection for a week. We made support treatment using mouthwashes for oral hygiene and corticoids ointment for ulcer protection, antihistaminics and nutritional guiding of a hypercaloric and hyperprotein liquid diet. This syndrome is characterized

  15. Media's contribution to sexual knowledge, attitudes, and behaviors for adolescents and young adults in three Asian cities.

    Science.gov (United States)

    Lou, Chaohua; Cheng, Yan; Gao, Ersheng; Zuo, Xiayun; Emerson, Mark R; Zabin, Laurie S

    2012-03-01

    Evidence in western countries indicates that the media have associations with adolescents' and young people's sexual behavior that may be as important as family, school, and peers. In this new study of Asian adolescents and young adults in the three cities of Hanoi, Shanghai, and Taipei, the associations between exposure to sexual content in the media and adolescents' and young adults' sex-related knowledge, attitudes, and behaviors are explored in societies with traditional Confucian culture, but at different stages in the process of modernization. The data are from a questionnaire-based cross-sectional study conducted from 2006 to 2007, where a sample of 17,016 adolescents and young adults aged 15-24 years from Shanghai, Hanoi, and Taipei completed face-to-face interviews coupled with computer-assisted self-interviews for sensitive questions. For the objectives of this article, analysis was restricted to the 16,554 unmarried respondents. Exposure to sexual content in the mass media (including the Internet and traditional media), pornographic videos, and a preference for western/Asian movies/videos were the main media influence measures. Sex-related knowledge, premarital sexual permissiveness (PSP), and sex-related behaviors were the main outcome measures. The impact of each of four contexts including family, peer, school, and media on sex-related knowledge, attitudes, and behaviors were assessed using multiple linear regression stratified by gender and city, controlling for age, urban/rural residence, education, and economic status. The change in adjusted R(2) from the multiple linear regression analysis was adopted to indicate the contribution of family, peer, school, and media variables to respondents' sex-related knowledge, attitudes, and behaviors. The contextual factors, including family, peer, school, and media, explained 30%-50% of the variance in sex-related knowledge, 8%-22% of the variance in PSP, and 32%-41% of the variance in sex-related behaviors

  16. Critical successful factors for innovation in vietnamese firms

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    Tran Hoai Nam

    2017-09-01

    Full Text Available Purpose: Innovation is considered as a core element of sustainable competitive advantage in the rapidly changing environment. However, in Vietnam, researches on innovation are very rare, which are mostly general reports without underlying analyses of innovation in firms, especially determinants for innovation. Therefore, this paper focuses on analyzing critical successful factors for innovation in Vietnamese firms.  Design/methodology/approach: This study used primary data through questionnaire survey from November 2015 to February 2016. Respondents were senior managers of firms located mostly at Hanoi (Northern, Hochiminh (Southern and Danang city (Central. The questionnaire included multi-items designed to measure factors. Each item was measured by 5 point Likert scale: 1 (strongly disagree to 5 (strongly agree. Questionnaires were administerd to 500 firms belonging to list of Vietnam Chamber of Commerce and Industry (VCCI in these three cities with rate of 40% (Hochiminh city, 40% (Hanoi city and Danang (20%. However, there were 360 returned questionnaires and valid to next analyses. Analysis methodologies of reliability, factor analysis and regression are utilized in this paper.  Findings: We developed and tested a model of determinants for Innovation in Vietnamese firms. The major contribution of this study is testing six determinants for innovation in Vietnamese companies. The results showed that awareness of innovation, innovation strategy and policy, organization for innovation, HR for innovation and building capabilities have positive impact on innovation.  Originality/value: This study makes a contribution for both academics and practitioners. For academics, this study provided one more empirical evidence of the determinants for innovation. Regarding practical implications, this study suggests that Vietnamese companies have to strengthen capabilities for employees through training, encourage generation of new ideas, rule breaking

  17. Antimicrobial susceptibility and genetic characteristics of Neisseria gonorrhoeae isolates from Vietnam, 2011

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    Olsen Birgitta

    2013-01-01

    Full Text Available Abstract Background Antimicrobial resistance (AMR in Neisseria gonorrhoeae is a major public health concern worldwide. In Vietnam, knowledge regarding N. gonorrhoeae prevalence and AMR is limited, and data concerning genetic characteristics of N. gonorrhoeae is totally lacking. Herein, we investigated the phenotypic AMR (previous, current and possible future treatment options, genetic resistance determinants for extended-spectrum cephalosporins (ESCs, and genotypic distribution of N. gonorrhoeae isolated in 2011 in Hanoi, Vietnam. Methods N. gonorrhoeae isolates from Hanoi, Vietnam isolated in 2011 (n = 108 were examined using antibiograms (Etest for 10 antimicrobials, Neisseria gonorrhoeae multi-antigen sequence typing (NG-MAST, and sequencing of ESC resistance determinants (penA, mtrR and penB. Results The levels of in vitro resistance were as follows: ciprofloxacin 98%, tetracycline 82%, penicillin G 48%, azithromycin 11%, ceftriaxone 5%, cefixime 1%, and spectinomycin 0%. The MICs of gentamicin (0.023-6 mg/L, ertapenem (0.002-0.125 mg/L and solithromycin (penA mosaic alleles were found, however, 78% of the isolates contained an alteration of amino acid A501 (A501V (44% and A501T (34% in the encoded penicillin-binding protein 2. A single nucleotide (A deletion in the inverted repeat of the promoter region of the mtrR gene and amino acid alterations in MtrR was observed in 91% and 94% of the isolates, respectively. penB resistance determinants were detected in 87% of the isolates. Seventy-five different NG-MAST STs were identified, of which 59 STs have not been previously described. Conclusions In Vietnam, the highly diversified gonococcal population displayed high in vitro resistance to antimicrobials previously recommended for gonorrhoea treatment (with exception of spectinomycin, but resistance also to the currently recommended ESCs were found. Nevertheless, the MICs of three potential future treatment options were low. It is

  18. Cigarette smoking is associated with high HIV viral load among adults presenting for antiretroviral therapy in Vietnam.

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    Todd M Pollack

    Full Text Available High HIV viral load (VL >100,000 cp/ml is associated with increased HIV transmission risk, faster progression to AIDS, and reduced response to some antiretroviral regimens. To better understand factors associated with high VL, we examined characteristics of patients presenting for treatment in Hanoi, Vietnam. We examined baseline data from the Viral Load Monitoring in Vietnam Study, a randomized controlled trial of routine VL monitoring in a population starting antiretroviral therapy (ART at a clinic in Hanoi. Patients with prior treatment failure or ART resistance were excluded. Characteristics examined included demographics, clinical and laboratory data, and substance use. Logistic regression was used to calculate crude and adjusted odds ratios (aOR and 95% confidence intervals (95% CI. Out of 636 patients, 62.7% were male, 72.9% were ≥30 years old, and 28.3% had a history of drug injection. Median CD4 was 132 cells/mm3, and 34.9% were clinical stage IV. Active cigarette smoking was reported by 36.3% with 14.0% smoking >10 cigarettes per day. Alcohol consumption was reported by 20.1% with 6.1% having ≥5 drinks per event. Overall 53.0% had a VL >100,000 cp/ml. Male gender, low body weight, low CD4 count, prior TB, and cigarette smoking were associated with high VL. Those who smoked 1-10 cigarettes per day were more likely to have high VL (aOR = 1.99, 95% CI = 1.15-3.45, while the smaller number of patients who smoked >10 cigarettes per day had a non-significant trend toward higher VL (aOR = 1.41, 95% CI = 0.75-2.66. Alcohol consumption was not significantly associated with high VL. Tobacco use is increasingly recognized as a contributor to premature morbidity and mortality among HIV-infected patients. In our study, cigarette smoking in the last 30 days was associated with a 1.5 to 2-fold higher odds of having an HIV VL >100,000 cp/ml among patients presenting for ART. These findings provide further evidence of the negative effects of

  19. Decreasing In-home Smoking of Adults—Results from a School-based Intervention Program in Viet Nam

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    Le Thi Thanh Huong

    2016-10-01

    Full Text Available It is indicated that children are involuntarily exposed to secondhand smoke from adults, mainly at their home environment. This study aimed at describing the effectiveness of the school-based intervention to decrease the in-home smoking situation of adults so as to decrease children’s exposure to secondhand smoke at home during the year 2011–2012 in a rural district in Hanoi, Viet Nam. This school-based intervention program (intervention and control group involved 804 children aged 8 to 11 years from August 2011 to May 2012 in a rural district of Hanoi, Viet Nam. Children were taught in class about the harmful effects of secondhand smoke and about how to negotiate with fathers not to smoke in-home. Then children applied what they learnt, including staying away from secondhand smoke and persuading fathers not to smoke in-home in order to decrease children’s exposure to secondhand smoke. Chi square test, t-test and multinominal logistic regression were applied in data analysis. The results showed that children’s reported their father’s in-home smoking decreased from 83.0% pre-intervention to 59.8% post-intervention (p < 0.001 in the intervention school while no change happened in the control school. The study found that the better changed smoking location of adult smokers as reported by children associated with the school who received intervention activities (adjusted OR = 2.04; 95% CI: 1.28–3.24. Poorer changed attitudes towards secondhand smoke of children associated with a lower percentage of better change in smoking location of their fathers/other adult smokers (aOR = 0.51, 95% CI: 0.28–0.96. Children’s poorer changed knowledge towards secondhand smoke also associated with poorer changed smoking location of adult smokers (aOR = 2.88, 95% CI: 1.07–7.76. It is recommended by this study that similar school based intervention approaches should be applied in primary schools in Viet Nam to increase children’s awareness on the

  20. Cigarette smoking is associated with high HIV viral load among adults presenting for antiretroviral therapy in Vietnam.

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    Pollack, Todd M; Duong, Hao T; Pham, Thuy T; Do, Cuong D; Colby, Donn

    2017-01-01

    High HIV viral load (VL >100,000 cp/ml) is associated with increased HIV transmission risk, faster progression to AIDS, and reduced response to some antiretroviral regimens. To better understand factors associated with high VL, we examined characteristics of patients presenting for treatment in Hanoi, Vietnam. We examined baseline data from the Viral Load Monitoring in Vietnam Study, a randomized controlled trial of routine VL monitoring in a population starting antiretroviral therapy (ART) at a clinic in Hanoi. Patients with prior treatment failure or ART resistance were excluded. Characteristics examined included demographics, clinical and laboratory data, and substance use. Logistic regression was used to calculate crude and adjusted odds ratios (aOR) and 95% confidence intervals (95% CI). Out of 636 patients, 62.7% were male, 72.9% were ≥30 years old, and 28.3% had a history of drug injection. Median CD4 was 132 cells/mm3, and 34.9% were clinical stage IV. Active cigarette smoking was reported by 36.3% with 14.0% smoking >10 cigarettes per day. Alcohol consumption was reported by 20.1% with 6.1% having ≥5 drinks per event. Overall 53.0% had a VL >100,000 cp/ml. Male gender, low body weight, low CD4 count, prior TB, and cigarette smoking were associated with high VL. Those who smoked 1-10 cigarettes per day were more likely to have high VL (aOR = 1.99, 95% CI = 1.15-3.45), while the smaller number of patients who smoked >10 cigarettes per day had a non-significant trend toward higher VL (aOR = 1.41, 95% CI = 0.75-2.66). Alcohol consumption was not significantly associated with high VL. Tobacco use is increasingly recognized as a contributor to premature morbidity and mortality among HIV-infected patients. In our study, cigarette smoking in the last 30 days was associated with a 1.5 to 2-fold higher odds of having an HIV VL >100,000 cp/ml among patients presenting for ART. These findings provide further evidence of the negative effects of tobacco use among

  1. The Ha Noi Expert Statement: recognition of maternal mental health in resource-constrained settings is essential for achieving the Millennium Development Goals

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    Izutsu Takashi

    2011-01-01

    Full Text Available Abstract Mental health problems in women during pregnancy and after childbirth and their adverse consequences for child health and development have received sustained detailed attention in high-income countries. In contrast, evidence has only been generated more recently in resource-constrained settings. In June 2007 the United Nations Population Fund, the World Health Organization, the Key Centre for Women's Health in Society, a WHO Collaborating Centre for Women's Health and the Research and Training Centre for Community Development in Vietnam convened the first international expert meeting on maternal mental health and child health and development in resource-constrained settings. It aimed to appraise the evidence about the nature, prevalence and risks for common perinatal mental disorders in women; the consequences of these for child health and development and ameliorative strategies in these contexts. The substantial disparity in rates of perinatal mental disorders between women living in high- and low-income settings, suggests social rather than biological determinants. Risks in resource-constrained contexts include: poverty; crowded living situations; limited reproductive autonomy; unintended pregnancy; lack of empathy from the intimate partner; rigid gender stereotypes about responsibility for household work and infant care; family violence; poor physical health and discrimination. Development is adversely affected if infants lack day-to-day interactions with a caregiver who can interpret their cues, and respond effectively. Women with compromised mental health are less able to provide sensitive, responsive infant care. In resource-constrained settings infants whose mothers are depressed are less likely to thrive and to receive optimal care than those whose mothers are well. The meeting outcome is the Hanoi Expert Statement (Additional file 1. It argues that the Millennium Development Goals to improve maternal health, reduce child

  2. Quality of life profile of general Vietnamese population using EQ-5D-5L.

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    Nguyen, Long Hoang; Tran, Bach Xuan; Hoang Le, Quynh Ngoc; Tran, Tung Thanh; Latkin, Carl A

    2017-10-11

    Health-related quality of life (HRQOL) is a vital benchmark to assess the effects of health interventions and policies. Measuring HRQOL of the general population is essential to establish a reference for health outcomes evaluations. However, evidence on HRQOL of general populations in low and middle income countries is very limited. This study aimed to measure HRQOL of the Vietnamese population by using the EuroQol-5 dimensions-5 levels (EQ-5D-5L) instrument and determine its associated factors. A cross-sectional study was performed in Hanoi with 1571 residences in Hanoi, the capital city of Vietnam. EQ-5D-5L and EQ- visual analogue scale (EQ-VAS) were used to assess HRQOL. Potential covariates included socio-demographic characteristics, having acute symptoms in the last four weeks, chronic diseases in the last three months, having multiple health issues, and health service utilisation in the last twelve months. A generalized linear model was employed to identify the association between HRQOL and covariates. Overall, the mean EQ-5D utility index was 0.91 (SD = 0.15), and the mean EQ-VAS score was 87.4 (SD = 14.3). The highest proportion of respondents reporting any problems was in Usual activities (24.3%), followed by Anxiety/Depression (15.2%) and Pain/Discomfort (10.0%), while the lowest percentage was in Self-care (2.5%). Lower HRQOL composite scores were related to unemployment, lower income, higher education, living in urban areas, having chronic diseases, having multiple health issues and using health service. For any health problem self-reported by respondents, the health utility reduced by 0.02 (respiratory diseases) to 0.15 (musculoskeletal diseases). Health utility of the general population and reductions for self-reported health problems in this study are useful for future population health evaluations and comparisons. It also informs the development of interventions to reduce health problems of the general population.

  3. Satellites may underestimate rice residue and associated burning emissions in Vietnam

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    Lasko, Kristofer; Vadrevu, Krishna P.; Tran, Vinh T.; Ellicott, Evan; Nguyen, Thanh T. N.; Bui, Hung Q.; Justice, Christopher

    2017-08-01

    In this study, we estimate rice residue, associated burning emissions, and compare results with existing emissions inventories employing a bottom-up approach. We first estimated field-level post-harvest rice residues, including separate fuel-loading factors for rice straw and rice stubble. Results suggested fuel-loading factors of 0.27 kg m-2 (±0.033), 0.61 kg m-2 (±0.076), and 0.88 kg m-2 (±0.083) for rice straw, stubble, and total post-harvest biomass, respectively. Using these factors, we quantified potential emissions from rice residue burning and compared our estimates with other studies. Our results suggest total rice residue burning emissions as 2.24 Gg PM2.5, 36.54 Gg CO and 567.79 Gg CO2 for Hanoi Province, which are significantly higher than earlier studies. We attribute our higher emission estimates to improved fuel-loading factors; moreover, we infer that some earlier studies relying on residue-to-product ratios could be underestimating rice residue emissions by more than a factor of 2.3 for Hanoi, Vietnam. Using the rice planted area data from the Vietnamese government, and combining our fuel-loading factors, we also estimated rice residue PM2.5 emissions for the entirety of Vietnam and compared these estimates with an existing all-sources emissions inventory, and the Global Fire Emissions Database (GFED). Results suggest 75.98 Gg of PM2.5 released from rice residue burning accounting for 12.8% of total emissions for Vietnam. The GFED database suggests 42.56 Gg PM2.5 from biomass burning with 5.62 Gg attributed to agricultural waste burning indicating satellite-based methods may be significantly underestimating emissions. Our results not only provide improved residue and emission estimates, but also highlight the need for emissions mitigation from rice residue burning.

  4. Prevalence of frailty and its associated factors in older hospitalised patients in Vietnam.

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    Vu, Huyen Thi Thanh; Nguyen, Thanh Xuan; Nguyen, Tu N; Nguyen, Anh Trung; Cumming, Robert; Hilmer, Sarah; Pham, Thang

    2017-09-15

    Frailty is an emerging issue in geriatrics and gerontology. The prevalence of frailty is increasing as the population ages. Like many developing countries, Vietnam has a rapidly ageing population. However, there have been no studies about frailty in older people in Vietnam. This study aims to investigate the prevalence of frailty and its associated factors in older hospitalised patients at the National Geriatric Hospital in Hanoi, Vietnam. Prospective observational study in inpatients aged ≥60 years at the National Geriatric Hospital in Hanoi, Vietnam from 4/2015 to 10/2015. Frailty was assessed using the Reported Edmonton Frail Scale (REFS) and Fried frailty phenotype. A total of 461 patients were recruited (56.8% female, mean age 76.2 ± 8.9 years). The prevalence of frailty was 31.9% according to the REFS. Using the Fried frailty criteria, the percentages of non-frail, pre-frail and frail participants were 24.5, 40.1 and 35.4%, respectively. Factors associated with frailty defined by REFS were age (OR 1.05 per year, 95% CI 1.03-1.08), poor reported nutritional status (OR 4.51, 95% CI 2.15-9.44), and not finishing high school (OR 2.18, 95% CI 1.37-3.46). Factors associated with frailty defined by the Fried frailty criteria included age (OR 1.07 per year, 95% CI 1.05-1.10), poor reported nutritional status (OR 2.96, 95%CI 1.43-6.11), not finishing high school (OR 1.58, 95% CI 1.01-2.46) and cardiovascular disease (OR 1.76, 95% CI 1.16-2.67). While further studies are needed to examine the impact of frailty on outcomes in Vietnam, the observed high prevalence of frailty in older inpatients is likely to have implications for health policy and planning for the ageing population in Vietnam.

  5. Behavioural research on human working memory: mixing qualitative and quantitative methods (Investigación conductual sobre memoria de trabajo: Integrando métodos cualitativos y cuantitativos

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    María de los Angeles Bacigalupe

    2013-12-01

    Full Text Available ABSTRACT: The long lasting opposition between qualitative and quantitative methods for studying behaviour has been overridden by interdisciplinary work in which methods can be combined to approach animal and human behaviour, thus contributing to drawing rigorous and useful conclusions. We show an example of this by combining a quasi-experimental design and descriptive methods to study working memory for the resolution of a spatial problem task (the Tower of Hanoi in a neuropsychiatric hospital inpatient with amnesia and executive deficits. Results from the quasi-experiment showed that the patient acquired strategies to solve the task with a high level of efficiency (F3/35 = 7, 19, p < .01. Qualitatively speaking, the patient developed more than one strategy to solve the problem, which indicates the presence of learning based on working memory. In the light of these findings, we discuss issues of mixed methods research and suggest the importance of developing mixed methods to study behaviour. RESUMEN: La oposición duradera entre métodos cualitativos y cuantitativos para estudiar el comportamiento ha sido anulada por el trabajo interdisciplinario en que los métodos pueden combinarse para enfocar el comportamiento humano y animal, contribuyendo así a obtener conclusiones útiles y rigurosas. Se presenta una muestra, combinando métodos descriptivos y un diseño cuasiexperimental para estudiar la memoria de trabajo en la resolución de una tarea de problema espacial (la Torre de Hanoi, en un paciente internado en un hospital neuropsiquiátrico con amnesia y déficit ejecutivo. Resultados del cuasiexperimento demostraron que el paciente adquirió estrategias para resolver la tarea con un alto nivel de eficiencia (F3/35 = 7, 19, p < .01. Cualitativamente el paciente desarrolló más de una estrategia para resolver el problema, lo cual indica la presencia de aprendizaje basado en memoria de trabajo. A la luz de estos resultados, se discuten m

  6. Impact of Prefrontal Theta Burst Stimulation on Clinical Neuropsychological Tasks

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    Raquel Viejo-Sobera

    2017-08-01

    Full Text Available Theta burst stimulation (TBS protocols hold high promise in neuropsychological rehabilitation. Nevertheless, their ability to either decrease (continuous, cTBS or increase (intermittent, iTBS cortical excitability in areas other than the primary motor cortex, and their consistency modulating human behaviors with clinically relevant tasks remain to be fully established. The behavioral effects of TBS over the dorsolateral prefrontal cortex (dlPFC are particularly interesting given its involvement in working memory (WM and executive functions (EF, often impaired following frontal brain damage. We aimed to explore the ability of cTBS and iTBS to modulate WM and EF in healthy individuals, assessed with clinical neuropsychological tests (Digits Backward, 3-back task, Stroop Test, and Tower of Hanoi. To this end, 36 participants were assessed using the four tests 1 week prior to stimulation and immediately following a single session of either cTBS, iTBS, or sham TBS, delivered to the left dlPFC. No significant differences were found across stimulation conditions in any of the clinical tasks. Nonetheless, in some of them, active stimulation induced significant pre/post performance modulations, which were not found for the sham condition. More specifically, sham stimulation yielded improvements in the 3-back task and the Color, Color-Word, and Interference Score of the Stroop Test, an effect likely caused by task practice. Both, iTBS and cTBS, produced improvements in Digits Backward and impairments in 3-back task accuracy. Moreover, iTBS increased Interference Score in the Stroop Test in spite of the improved word reading and impaired color naming, whereas cTBS decreased the time required to complete the Tower of Hanoi. Differing from TBS outcomes reported for cortico-spinal measures on the primary motor cortex, our analyses did not reveal any of the expected performance differences across stimulation protocols. However, if one considers independently

  7. Neighborhood informal social control and child maltreatment: A comparison of protective and punitive approaches.

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    Emery, Clifton R; Trung, Hai Nguyen; Wu, Shali

    2015-03-01

    This paper introduces a new measure of informal social control of child maltreatment (henceforth ISC_CM) by neighbors. Research literature typically uses collective efficacy (Sampson, Raudenbush, & Earls, 1997) to examine neighborhood informal social control. We argue that double standards about the application of informal social control to family versus street crime requires a measure of informal social control specific to child maltreatment. We also argue that how neighbors intervene may matter as much as whether they intervene. Neighbors may engage in ISC_CM aimed at protecting the child and calming the parent, or more punitive ISC_CM aimed at deterring future abuse. We tested the relationship of both with very severe physical abuse and with abuse related child behavior problems. We used a random, 2-stage cluster design of Hanoi to collect the sample. Thirty Hanoi wards were randomly selected using probability proportional to size sampling. A simple random sample of families in each ward was then drawn using local government lists of ward residents. Based on power analysis, the target sample size was 300. Of 315 residents contacted, 293 participated, yielding a response rate of 93%. Random effects regression models (which estimate a random effect for each ward) were run in Stata11. We found that protective ISC_CM is associated with lower odds of very severe physical abuse and lower reported externalizing problems when abuse is present. Perceived collective efficacy and punitive ISC_CM is not associated with lower odds of very severe physical abuse. Implications for research, policy and practice are discussed. We conclude that further investigation of neighbor ISC_CM is needed to replicate the findings in other cultural contexts, ultimately followed by experimental manipulation of ISC_CM in a neighborhood context to examine the effects on child maltreatment. If further research corroborates the current findings, the development of neighborhood intervention

  8. The good pharmacy practice on Einstein Program at Paraisópolis Community.

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    Oliveira, Lara Tânia de Assumpção Domingues Gonçalves de; Silva, Camila Pontes da; Guedes, Maria das Vitorias; Sousa, Ana Célia de Oliveira; Sarno, Flávio

    2016-01-01

    To describe indicators and processes developed and implemented for pharmaceutical assistance at the Einstein Program at Paraisópolis Community pharmacy. This was a descriptive study of retrospective data from January 2012 to December 2015. Data were obtained from spreadsheets developed for monitoring the productivity and care quality provided at the pharmacy. The evaluated variables were pharmaceutical assistance to prescription, pharmaceutical intervention, orientation (standard and pharmaceutical) and pharmaceutical orientation rate. The pharmacy assisted, on average, 2,308 prescriptions monthly, dispensing 4,871 items, including medications, materials and food supplements. Since March 2015, virtually, the pharmacist analyzed all prescriptions, prior to dispensing. In the analyzed period, there was an increase in monthly pharmaceutical interventions from 7 to 32 on average, and, although there was a decrease in the number of standard orientation, the pharmaceutical orientation had an increase, causing a rise of pharmaceutical orientation rate from 4 to 11%. The processes developed and implemented at the program pharmacy sought to follow the good pharmacy practice, and help patients to make the best use of their medications. Descrever os indicadores e os processos desenvolvidos e implantados para assistência farmacêutica na farmácia do Programa Einstein na Comunidade de Paraisópolis. Tratase de um estudo descritivo de dados retrospectivos de janeiro de 2012 a dezembro de 2015. Os dados foram obtidos de planilhas desenvolvidas para acompanhamento da produtividade e da qualidade de assistência prestada na farmácia. As variáveis avaliadas foram: atenção farmacêutica à prescrição, intervenção farmacêutica, orientação (padrão e farmacêutica) e taxa de orientação farmacêutica. A farmácia atendeu, em média, 2.308 prescrições ao mês, dispensando 4.871 itens, incluindo medicamentos, materiais e suplementos alimentares. Desde março de 2015

  9. Parametria da associação do midazolam ou diazepam em cães pré-tratados pela atropina e tratados pela dexmedetomidina e quetamina

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    Hatschbach Eduardo

    2006-01-01

    Full Text Available Em Anestesiologia Veterinária, busca-se continuamente a contenção farmacológica para estabelecer tratamentos, cruentos ou não, permitindo manipulações seguras e duradouras, dispensando a anestesia geral sem alterar, sobremaneira, os parâmetros fisiológicos. Visou-se empregar a dexmedetomidina em associação com a quetamina e o midazolam ou diazepam. A técnica anestésica foi aplicada em 30 cães hígidos, machos ou fêmeas, com pesos de 10 a 15kg e idades de 2 a 4 anos, distribuídos aleatoriamente em três grupos (GI, GII, GIII. O grupo I recebeu um pré-tratamento de atropina (0,044mg kg-1 SC, e após 15 minutos, a dexmedetomidina (3mg kg-1 IV, em dose única, aplicada durante dois minutos e uma dose de manutenção de dexmedetomidina (3mg kg h-1 juntamente com a quetamina (2mg kgh-1, completando-se para 20ml de solução fisiológica para infusão contínua, perfazendo uma hora de aplicação. O grupo II recebeu o mesmo tratamento de GI, entretanto, recebeu juntamente com a dexmedetomidina, o midazolam (0,2mg kg-1 IV durante os dois minutos e outra dose, de 0,2mg kg h-1 junto com a dose de manutenção da dexmedetomidina e quetamina. O grupo III recebeu o mesmo tratamento de GII só que ao invés do midazolam, foi usado o diazepam (0,5mg kg-1 IV como dose de indução e 0,5mg kg h-1 junto com a dose de manutenção. Foi avaliado o efeito das benzodiazepinas frente à associação anestésica, além dos parâmetros respiratórios, oxicapnométricos, índice bispectral e período de recuperação. Após o término da colheita, a avaliação estatística foi efetuada por meio de Análise de Perfil. A partir dos resultados obtidos, pode-se concluir que a associação dos benzodiazepínicos promoveu sinergismo na sedação e miorrelaxamento, além de estabilidade cardiorrespiratória após pré-tratamento com atropina, sendo de grande valia como contenção farmacológica.

  10. Infecções anais pelo papilomavírus humano, crioterapia e crioimunologia Anal infections by human papillomavirus, criotherapy, and cryoimunology

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    Raphael Marianelli

    2011-03-01

    Full Text Available As verrugas genitais causadas pelo papilomavírus humano (HPV são problemas comuns na prática clínica do coloproctologista. As opções terapêuticas são numerosas, não havendo padrão-ouro para o tratamento dos condilomas. Dentre elas, é possível destacar a crioterapia, que é eficaz, apesar de pouco utilizada. O efeito destrutivo da crioterapia ocorre por lesão celular direta, causada pelo frio, e por anóxia tecidual, consequente às alterações microcirculatórias. Dentre as vantagens do método, cita-se a segurança; a simplicidade de aplicação; o uso dentro e fora do canal anal, inclusive durante a gestação; e o desconforto local leve, dispensando anestesia. Os agentes criogênicos mais utilizados são o nitrogênio líquido e, mais recentemente, o dimetiléter-propano. Uma vantagem adicional é observada no tratamento das lesões neoplásicas e seus precursores. Postula-se que seu congelamento induziria à resposta imune antitumoral, consequente ao mecanismo de lesão tecidual, que expõe grande quantidade de antígenos intracelulares aos macrófagos e às células dendríticas. Entretanto, a literatura médica ainda carece de estudos abordando especificamente o tema, sobretudo na área da coloproctologia. De qualquer forma, podemos afirmar que a crioterapia é método eficaz, seguro, confortável e prático para o tratamento das verrugas anogenitais induzidas pelo HPV.Genital warts caused by human papillomavirus (HPV are a common problem in clinical practice of colorectal surgeons. There are several therapeutic options, although, there is not a gold standard for the treatment of condilomas. Among them, we could mention cryotherapy, which is an effective method, despite having little use. The destructive effect of cryotherapy is through direct cellular injury, which is provoked by cold, and tissue anoxia, due microcirculatory changes. Among the method advantages, we could relate safety; simplicity of application; use inside

  11. Tratamento cirúrgico da ginecomastia com pedículos lateral e medial

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    Miguel Modolin

    ginecomastia, com média etária de 23,3 anos; sendo seis pacientes da raça negra. O bom posicionamento do complexo aréolo-mamilar e uma cicatriz periareolar resultante, bem como a retirada de conteúdo suficiente, foram as principais vantagens observadas. Como complicações, tivemos assimetria das placas aréolo-mamilares em dois casos, nos quais havia acentuada diferença entre os dois lados na avaliação pré-operatória; cicatrização hipertrófica em um paciente da raça negra, cuja cicatriz foi atenuada com injeções intracicatriciais de triancinolona; necrose parcial de aréola em um caso, cuja ferida cicatrizou por segunda intenção, dispensando qualquer tratamento local posterior; deiscência de sutura periareolar em um caso, no qual foi feita a ressutura, com bom resultado, e quatro pacientes apresentaram coleção sero-hemática subcutânea, que foram drenadas e não apresentaram recidiva.

  12. O papel do ecocardiograma como método isolado na indicação cirúrgica de pacientes portadores de cardiopatia congênita The role of echocardiography as an isolated method for indicating surgery in patients with congenital heart disease

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    Lilian Maria Lopes

    2005-05-01

    Full Text Available OBJETIVO: Determinar a acurácia diagnóstica do ecocardiograma, analisando prospectivamente, o valor do método na indicação cirúrgica sem cateterismo em portadores de cardiopatia congênita, através da comparação do diagnóstico ecocardiográfico com os achados intra-operatórios e/ou do estudo invasivo. MÉTODOS: De fevereiro/2000 a janeiro/2001, foram acompanhados 493 pacientes cardiopatas congênitos com indicação cirúrgica, submetidos a ecocardiograma com mapeamento de fluxo em cores para decisão terapêutica. Os resultados foram comparados aos achados cirúrgicos e/ou de cateterismo quando realizado para complementação diagnóstica. RESULTADOS: Dos pacientes estudados, 94,3% (465 casos foram submetidos à correção da cardiopatia congênita apenas com o ecocardiograma e sem cateterismo diagnóstico. O estudo invasivo foi realizado para complementação diagnóstica em 28 (5,6% casos, o tratamento cirúrgico realizado em mais de 95% dos casos e o cateterismo terapêutico em 3,6%. Os achados do ecocardiograma se confirmaram em 464 (94,1% dos casos, demonstrando uma alta acurácia do método. Ocorreram 8 (1,6% casos de falso positivos e 39 (7,9% casos de falso negativos. Segundo os cirurgiões, nenhum dos erros diagnósticos levaram a complicações ou afetaram os resultados cirúrgicos adversamente. CONCLUSÃO: O ecocardiograma se mostrou método sensível e seguro para indicação cirúrgica, dispensando, muitas vezes, a realização de estudo invasivo, ficando este, restrito aos casos de complementação diagnóstica ou terapêutica.OBJECTIVE: To determine the diagnostic accuracy of echocardiography for indicating surgery without catheterization in patients with congenital heart disease through a prospective analysis and comparison of the echocardiographic diagnosis with the intraoperative findings, or invasive study, or both. METHODS: From February 2000 to January 2001, 493 patients with congenital heart diseases indicated

  13. Simplificação do método de estimação da densidade larvária de Aedes aegypti no Estado de São Paulo Simplifying the sampling method for evaluating the larval density of Aedes aegypti in Brazil

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    Maria Cecília Goi Porto Alves

    2001-10-01

    Full Text Available OBJETIVO: Propor alterações simplificadoras em plano de amostragem para estimar a densidade larvária de Aedes aegypti, partindo da avaliação de sua eficiência e simplicidade. MÉTODOS: Avaliou-se o plano de amostragem utilizado pela Superintendência de Controle de Endemias do Estado de São Paulo, para estimar a densidade larvária de Aedes aegypti pelo índice de Breteau, utilizando amostragem por conglomerados (quadras em uma única etapa. Foram avaliadas 111 amostras obtidas em seis municípios da região de São José do Rio Preto, e pesquisadas, em média, 35 quadras e 14 edificações por quadra, num total de 510 edificações por amostra. RESULTADOS: As estimativas do índice de Breteau superiores a 3 apresentaram coeficientes de variação menores que 30% em 71% das amostras. O efeito do delineamento foi de 1,19 e de 1,79 para índices menores e maiores que 5, respectivamente. As estimativas foram obtidas em menos de três dias, envolvendo, em média, 5,5 homens na coleta de dados por dia. CONCLUSÕES: O plano de amostragem apresentou características de método simplificado: rapidez, economia e fácil operacionalização. Tais resultados se devem principalmente à utilização de conglomerados em uma única etapa, dispensando elaboração de listagem de endereços, sorteio e localização de edificações na segunda etapa. O efeito do delineamento indicou perda de precisão em níveis aceitáveis com a utilização de uma só etapa. A determinação do tamanho da amostra e a estimação dos erros amostrais das estimativas mereceram alterações simplificadoras.OBJECTIVE: To suggest changes in the sampling procedures for estimating the larval density of Aedes aegypti in the state of São Paulo, Brazil, by assessing the efficacy and level of complexity of the current procedures. METHODS: The "Superintendência de Controle de Endemias do Estado de São Paulo" -- SUCEN's (Superintendence for Endemic Control of the State of São Paulo

  14. Prostituição juvenil feminina e a prevenção da Aids em Ribeirão Preto, SP Female juvenile prostitution and AIDS prevention programs in Brazil

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    Cristiane Paulin Simon

    2002-08-01

    Full Text Available OBJETIVOS: Investigar as percepções sobre a Aids para o desenvolvimento de programas de prevenção de Aids com a prostituição juvenil feminina. MÉTODOS: Foram entrevistadas 13 jovens com idades entre 18 e 21 anos, que trabalham como prostitutas na cidade de Ribeirão Preto, por meio de um roteiro semi-estruturado com questões referentes a: dados sociodemográficos; conhecimentos sobre Aids; comportamentos sexuais; tipos de relacionamentos com clientes, namorados ou companheiros; e sugestões para programas de prevenção de doenças sexualmente transmissíveis (DST e Aids. RESULTADOS: Embora todas as entrevistadas tenham demonstrado conhecimento sobre HIV e práticas sexuais seguras, essas informações se contradizem com a crença no destino como o determinante para a infecção pelo HIV, bem como com a busca de afetividade nos relacionamentos, seja com o companheiro, namorado ou cliente fixo. Essas contradições agem como possíveis fatores impeditivos para adoção de comportamentos preventivos consistentes. CONCLUSÕES: As estratégias de prevenção para o HIV e a Aids devem levar em consideração que é necessário criar espaços nos quais se possibilitem a discussão e reflexão, que facilitem a clarificação de crenças e concepções que ainda fazem parte do imaginário social desse segmento social sobre a Aids. Também são necessárias discussões sobre os envolvimentos afetivos que são percebidos como relacionamentos imunes, dispensando a negociação de práticas preventivas. Outro ponto fundamental é o tipo de abordagem a ser utilizado para contatar as jovens. Estratégias sensíveis às características das jovens deverão ser empregadas.OBJECTIVE: To investigate perception of AIDS and to obtain information for developing AIDS prevention programs targeting female juvenile prostitution. METHODS: Thirteen young women aged 18 to 21 years working as prostitutes in the city of Ribeirão Preto, Brazil, were interviewed using

  15. Uso de fungos micorrízicos arbusculares (FMA na promoção do crescimento de mudas de pinheira (Annona squamosa L., Annonaceae Use of arbuscular mycorrhizal fungi (AMF to promote the growth of sugar apple seedlings (Annona squamosa L. Annonaceae

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    Ieda Ribeiro Coelho

    2012-12-01

    Full Text Available Os fungos micorrízicos arbusculares (FMA podem ser usados na formação de mudas frutíferas, porém o seu efeito na pinheira não é conhecido. Foi investigado o papel de dois isolados de FMA (Acaulospora longula e Gigaspora albida na promoção do crescimento de mudas de pinheira. O delineamento experimental foi tipo inteiramente casualizado em seis tratamentos: 1 Controle não inoculado em solo; 2 Controle não inoculado em solo adubado; 3 Inoculado com A. longula em solo; 4 Inoculado com A. longula em solo adubado; 5 Inoculado com G. albida em solo; 6 Inoculado com G. albida em solo adubado, em quatro repetições, totalizando 24 unidades. Plântulas com duas folhas foram inoculadas na região das raízes com solo-inóculo fornecendo 200 esporos de G. albida ou de A. longula. Após 140 dias em casa de vegetação avaliou-se: altura, número de folhas, diâmetro do caule, área foliar, massa fresca e seca da parte aérea e radicular, colonização micorrízica e produção de esporos de FMA. Em solo não adubado, os benefícios da micorrização foram evidenciados nas mudas formando simbiose com G. albida. Em solo com vermicomposto, a micorrização não incrementou o crescimento da mudas. A micorrização com G. albida pode ser alternativa para produção de mudas de pinheira, dispensando a fertilização.Arbuscular mycorrhizal fungi (AMF can be used to promote seedling growth of fruit trees, but their effect on sugar apple is not known. We investigated the role of two isolates of AMF (Acaulospora longula and Gigaspora albida in promoting the growth of sugar apple seedlings. The experimental design was completely randomized with six treatments and four replicates (totaling 24 units: 1 uninoculated control; 2 uninoculated control in fertilized soil; 3 inoculated with A. longula in soil, 4 inoculated with A. longula in fertilized soil, 5 inoculated with G. albida in soil; 6 inoculated with G. albida in fertilized soil. Seedlings with two

  16. Avaliação Clínica e Laboratorial de Crianças e Adolescentes com Queixas Vulvovaginais Clinical and Laboratorial Evaluation of Children and Teenagers with Vulvovaginal Complaints

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    Miriam da Silva Wanderley

    2000-04-01

    Full Text Available Objetivo: analisar as queixas vulvovaginais mais freqüentemente observadas no Ambulatório de Ginecologia Infanto-puberal (AGIP do Hospital Universitário de Brasília (HUB. Métodos: foram avaliados retrospectivamente 210 prontuários de meninas, até 18 anos de idade, que procuraram o AGIP/HUB com queixas vulvovaginais. Analisaram-se as queixas mais freqüentes e os agentes etiológicos mais observados à secreção vaginal. Resultados: a idade média das 210 pacientes estudadas, até dezoito anos, foi de 12 ± 2,3 anos e as queixas mais comuns foram o corrimento vaginal e o prurido vulvar. Alterações inflamatórias inespecíficas foram observadas em 147 destas pacientes (70% as quais foram tratadas com orientação a respeito de vestuário, de atividades diárias e de higiene. As outras 63 pacientes, nas quais foi observado um agente etiológico específico, necessitaram de tratamento medicamentoso apropriado. Somente em pacientes com vida sexual ativa foram observados infecções por Gardnerella vaginalis, Trichomoma vaginalis, HPV, assim como sífilis. Para estas pacientes a idade da sexarca foi de 14,1 ± 1,6 anos. Vinte pacientes apresentaram queixas vulvares concomitantemente, de fácil manuseio e orientação. Conclusão: higiene, vestuário e orientação adequada às pacientes e seus familiares são fundamentais para o controle e tratamento das queixas vulvovaginais, quase sempre dispensando o uso de antimicrobianos.Purpose: to assess the commonest vulvovaginal complaints and vaginal discharge etiology in the Child and Teenager Gynecologic Outpatient Clinic of the University Hospital of Brasília (AGIP/HUB. Methods: we evaluated retrospectively 210 charts of patients, younger than 19 years old, who attended AGIP/HUB with vulvovaginal complaints. Results: the average age of the 210 patients was 12 ± 2.3 years, and the vaginal discharge and vulvar pruritus were the commonest complaints. Unspecific inflammatory conditions were

  17. Análise inelástica de segunda ordem em pórticos planos de aço

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    Alex Sander Clemente de Souza

    2016-08-01

    Full Text Available RESUMO: Na análise estrutural de edifícios é necessária e exigida em códigos de projeto a consideração do comportamento não-linear do material e da estrutura para determinação de esforços e deslocamentos. O desenvolvimento de novos softwares permite a realização de análises mais rigorosas, como a análise avançada, em que é possível avaliar a capacidade resistente e a estabilidade da estrutura dispensando a verificação dos elementos isolados e ainda considerando os efeitos não-lineares, sejam eles físicos e/ou geométricos. Por outro lado, os códigos normativos ainda permitem procedimentos simplificados para a análise estrutural, embora seja relativamente comum o uso de métodos mais avançados de análise, como por exemplo, o Método dos Elementos Finitos. Pretende-se, com este estudo, fornecer subsídios para a compreensão dos códigos normativos e a importância da escolha do modelo de análise estrutural na fase de projeto. Neste contexto, a fim de exemplificar, os efeitos das não-linearidades geométrica e física sobre o comportamento da estrutura foram avaliados pórticos planos em aço por meio de modelagem avançada. Além disso, uma modelagem com elementos finitos de barra / mola foi desenvolvida e os resultados obtidos se mostraram compatíveis com aqueles dos modelos tridimensionais onde os perfis foram modelados com elementos de chapa. Desta forma contribui-se para ampliar o estado da arte sobre análise estrutural de forma integrada com o dimensionamento de estruturas metálicas. ABSTRACT: In structural analysis of buildings it is necessary and required in design codes include non -linear effects on the material and structure for determining forces and displacements. The development of new software allows more rigorous analyzes, such as the advanced analysis; it is possible to assess the strength and stability of a structure excusing the verification of separate structural elements and considering the

  18. Gastrostomia de incisão única como alternativa para o procedimento endoscópico

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    Ricardo Zorrón

    fístula ou peritonite. CONCLUSÕES: Os resultados desta casuística inicial sugerem que a abordagem é efetiva em propiciar um acesso rápido e seguro para gastrostomia, com ferida única, dispensando o uso de suporte endoscópico e anestesia geral. Pode ser utilizado como opção ao método endoscópico em pacientes com obstrução neoplásica faríngea ou esofageana. Uma casuística mais expressiva, acompanhamento mais longo dos casos, e estudos prospectivos randomizados são necessários para estabelecer o papel desta nova técnica na rotina cirúrgica.

  19. Estado epiléptico, consideraciones sobre manejo y tratamiento

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    Solari B. Francesca, Dra.

    2013-11-01

    Full Text Available El estado epiléptico es una emergencia médica. Existen diversas definiciones de estado epiléptico y clasificaciones según etiología, tipo de crisis y respuesta a terapia. En esta revisión, se adopta la variable tiempo como fundamental en el manejo del paciente. Otro concepto que se resalta, es la sospecha frente a pacientes graves o con ciertas patologías, la posibilidad de presentar estado epiléptico no convulsivo, ya que la identificación de este, podría mejorar el manejo del paciente grave. Las benzodiacepinas siguen siendo la terapia de primera línea, con una muy buena tasa de respuesta, cuanto más precoz se adopte la terapia. Se discuten diferentes terapias de segunda línea (fenitoína, fenobarbital, valproato, levetiracetam y midazolam y se mencionan aquellas de tercera línea, tanto farmacológicas como otras (dieta cetogénica, inmunosupresores, corticoides y cirugía.

  20. Láser de diodo; opción terapéutica para liquen plano erosivo resistente a corticoterapia: reporte de caso

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    Sandra Milena Espitia-Nieto

    2016-02-01

    Full Text Available Laser therapy is a new treatment option for its analgesic, anti-inflammatory and bio-stimulants properties and without significant adverse effects, for diseases such as oral Lichen Planus in its erosive form, characterized by chronic and painful ulcers with possibility of malignization, which obliges an adequate therapy. This article reports the clinical case taking into account ethical considerations framed in law 008430 of 1993 of a female patient 50 years old, with clinical and histopathological diagnosis of oral erosive Lichen Planus, who received initial treatment with corticoids local and systemic without improvement in 7 months; reason why is opted biostimulation with 980nm diode laser therapy, showing a significant reduction in the severity of injuries and decrease of pain from the first cycle of irradiation. Diode laser is safe and effective in this type of diseases treatment because it promotes healing, therefore it can be considered as an excellent alternative in cases of oral Lichen Planus resistant to corticotherapy.

  1. Absceso subperióstico de la órbita de foco dentario: reporte de un caso

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    Félix Antonio Torres Cotrina

    2005-01-01

    Full Text Available Un paciente varón de 35 años fue admitido en el Servicio de Oftalmología del Hospital Nacional Arzobispo Loayza con una historia de 15 días de proptosis, diplopía, limitación de la motilidad ocular, dolor y agudeza visual de cuenta dedos a 40 cm en su ojo izquierdo. No hubo antecedentes de fiebre, trauma, sinusitis, ni evidencia de medicación previa. Tuvo caries dentales sin tratamiento. Se instaló terapia con corticoide pensando en un síndrome inflamatorio inespecífico de la órbita. Una semana después se obtuvo material purulento después de una aspiración con aguja fina, por lo que se inició terapia antibiótica. Luego de la punción-aspiración los signos orbitarios empeoraron pero a los pocos días se obtuvo buena respuesta. Se discute el caso y se revisa la literatura pertinente.

  2. The infiltration of the AC joint performed by one specialist: Ultrasound versus palpation a prospective randomized pilot study

    Energy Technology Data Exchange (ETDEWEB)

    Sabeti-Aschraf, M., E-mail: manuel.sabeti-aschraf@meduniwien.ac.a [Vienna Medical School, Department for Orthopaedics and Orthopaedic Surgery, AKH-Wien, Waehringer Guertel18-20, 1090 Vienna (Austria); Ochsner, A. [Vienna Medical School, Department for Orthopaedics and Orthopaedic Surgery, AKH-Wien, Waehringer Guertel18-20, 1090 Vienna (Austria); Schueller-Weidekamm, C. [Vienna Medical School, Department for Radiology, AKH-Wien, Waehringer Guertel 18-20, 1090 Vienna (Austria); Schmidt, M. [Vienna Medical School, Department for Orthopaedics and Orthopaedic Surgery, AKH-Wien, Waehringer Guertel18-20, 1090 Vienna (Austria); Funovics, Ph.T. [Vienna Medical School, Department for Radiology, AKH-Wien, Waehringer Guertel 18-20, 1090 Vienna (Austria); Skrbensky, G. von [Vienna Medical School, Department for Orthopaedics and Orthopaedic Surgery, AKH-Wien, Waehringer Guertel18-20, 1090 Vienna (Austria); Goll, A. [Vienna Medical School, Core Unit for Medical Statistics and Wien, Waehringer Guertel18-20, 1090 Vienna (Austria); Schatz, K.D. [Vienna Medical School, Department for Orthopaedics and Orthopaedic Surgery, AKH-Wien, Waehringer Guertel18-20, 1090 Vienna (Austria)

    2010-07-15

    Introduction: The acromio-clavicular (AC) joint is very susceptible to degenerative processes that result in pain and functional impairment. One common modality of treatment has been local infiltration of the joint space. Although this procedure has produced notable positive results, needle misplacement occurs frequently. The aim of this investigation is to evaluate the effects of an intra articular infiltration by comparing precise needle placement into the joint space using high-resolution-ultrasound with the conventional palpation technique. Methods: This prospective and randomized pilot study analysed 20 patients who were assigned either to the 'ultrasound' or the 'palpation' group. Clinical examinations were performed before treatment and at 1 h, 1 week and 3 weeks after a single infiltration of local anaesthetic and corticoid carried out by one specialist. Results: In both groups significant improvement in pain and function was obtained up to one-week post injection. Function remained significantly improved until the last follow-up and did not differ between the two groups. The agent was administered in all patients into the joint space in the ultrasound group. Conclusion: Ultrasound guided infiltration of the AC joint is an easily achieved procedure without any complications. However, clinical follow-up did not differ between free-hand and ultrasound-guided AC joint space infiltration.

  3. General Stress Responses in the Honey Bee

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    Naïla Even

    2012-12-01

    Full Text Available The biological concept of stress originated in mammals, where a “General Adaptation Syndrome” describes a set of common integrated physiological responses to diverse noxious agents. Physiological mechanisms of stress in mammals have been extensively investigated through diverse behavioral and physiological studies. One of the main elements of the stress response pathway is the endocrine hypothalamo-pituitary-adrenal (HPA axis, which underlies the “fight-or-flight” response via a hormonal cascade of catecholamines and corticoid hormones. Physiological responses to stress have been studied more recently in insects: they involve biogenic amines (octopamine, dopamine, neuropeptides (allatostatin, corazonin and metabolic hormones (adipokinetic hormone, diuretic hormone. Here, we review elements of the physiological stress response that are or may be specific to honey bees, given the economical and ecological impact of this species. This review proposes a hypothetical integrated honey bee stress pathway somewhat analogous to the mammalian HPA, involving the brain and, particularly, the neurohemal organ corpora cardiaca and peripheral targets, including energy storage organs (fat body and crop. We discuss how this system can organize rapid coordinated changes in metabolic activity and arousal, in response to adverse environmental stimuli. We highlight physiological elements of the general stress responses that are specific to honey bees, and the areas in which we lack information to stimulate more research into how this fascinating and vital insect responds to stress.

  4. Eritema multiforme mayor desencadenado por antimicrobianos

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    Ronaldo de Carvalho Raimundo

    2010-03-01

    Full Text Available El eritema multiforme, aparece como una enfermedad sistémica con la participación de la piel y las membranas mucosas en relación con varios factores como las infecciones bacterianas o virales, y en particular la administración de drogas, analgésicos y antibióticos en general. Se presenta un paciente masculino de 29 años de edad con eritema multiforme mayor desencadenado por antimicrobianos con la aparición de lesiones vesiculares-bulloso-ulcerosas en las regiones de los labios, encías, la lengua y la mucosa genital en tratamiento de una infección del tracto urinario con norfloxacino 400 mg por una semana. Fue realizado un tratamiento de soporte con el uso de colutorios para la higienización bucal y pomada a base de corticoide para protección de las úlceras, antihistamínicos y orientación nutricional de dieta líquida hipercalórica e hiperproteica. Este síndrome está caracterizado como un proceso eruptivo buloso agudo que compromete la calidad de vida del paciente y no hay pruebas de laboratorio específicas por lo que su diagnóstico debe estar basado en la revisión minuciosa de la anamnesis y en los hallazgos clínicos.

  5. Stevens-Johnson syndrome from tetrazepam.

    Science.gov (United States)

    Sánchez, I; García-Abujeta, J L; Fernández, L; Rodríguez, F; Quiñones, D; Duque, S; López, R; Jerez, J

    1998-01-01

    We present a case of a patient showing a cutaneous and systemic affectation compatible with the Stevens-Johnson syndrome due to the intake of tetrazepam as a muscular relaxant. The symptoms remitted after the suspension of the involved medicines and after treatment with systemic corticoids. Months later, a study with patch tests, with the standard battery and the medicines that she took (indapamide, tetrazepam, acetyl salicylic acid, botriozolam and levomepromazine) was carried out. She presented positivity to tetrazepam at 48 and 96 hours. The oral provocations with the other medicines, which she consumed, were negative. The study of cross reactivity with other benzodiazepines was negative. In the medical literature, different cutaneous affectations regarding benzodiazepine use (generalised drug eruptions, contact dermatitis, erythema multiforme, ...) have been described byt non Stevens-Johnson syndrome. The patch tests are useful in the diagnosis of this type of cutaneous reactions, avoiding in this way the achievement of oral provocations, with the potential risk for the patient that they imply. The absence of cross-reactions with other substances of the same group has to be pointed out, even with those with which keeps great structural similarity as the diazepam. In spite of the absence of cross reactions with the rest of benzodiazepines, faced with the seriousness of the case presented, it is advised to the patient to avoid this type of medicines.

  6. Whitening Agents from Reseda luteola L. and Their Chemical Characterization Using Combination of CPC, UPLC-HRMS and NMR

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    Pauline Burger

    2017-11-01

    Full Text Available Skin whitening agents occupy an important part of the dermo-cosmetic market nowadays. They are used to treat various skin pigmentation disorders, or simply to obtain a lighter skin tone. The use of traditional skin bleachers (e.g., hydroquinone, corticoids is now strictly regulated due to their side effects. When considering this and the growing consumers’ interest for more natural ingredients, plant extracts can be seen as safe and natural alternatives. In this perspective, in vitro bioassays were undertaken to assess cosmetic potential of Reseda luteola, and particularly its promising whitening activities. A bioguided purification procedure employing centrifugal partition chromatography, Ultra Performance Liquid Chromatography-Mass Spectrometry (UPLC-HRMS and NMR was developed to isolate and identify the whitening agents (i.e., luteolin and apigenin from aerial parts of R. luteola. UPLC-HRMS also enabled the characterization of acetylated luteolin- and apigenin-O-glycosides, which occurrence is reported for the first time in R. luteola.

  7. Evaluating adrenal activity in African wild dogs (Lycaon pictus) by fecal corticosteroid analysis.

    Science.gov (United States)

    Monfort, S L; Mashburn, K L; Brewer, B A; Creel, S R

    1998-06-01

    A noninvasive corticosteroid hormone monitoring technique was validated for use in African wild dogs (Lycaon pictus). The double-antibody 125I radioimmunoassay for corticosterone was validated by demonstrating parallelism between serial dilutions of wild dog fecal extracts and the standard curve, recovery of corticosterone added to fecal extracts, and the time course of fecal corticoid excretion after an exogenous adrenocorticotropic hormone (ACTH) challenge. All feces were collected from three female and two male African wild dogs for 72 hr before and 144 hr after i.m. injection of long-acting ACTH (Acthar Gel, 400 IU). Fecal corticosterone immunoreactivity increased 10-30-fold within 24 hr of ACTH administration in all individuals, with peak concentrations from 1,200-8,000 ng/g. High-pressure liquid chromatography analysis revealed that >90% of all corticosterone immunoreactivity was associated with a single peak that exhibited intermediate polarity relative to cortisol and corticosterone reference tracers. Fecal corticosterone immunoreactivity appears to reflect adrenal activity in the African wild dog and, therefore, may be useful for evaluating stress. From a conservation perspective, these techniques can complement in situ and ex situ research studies designed to evaluate how environmental conditions and management strategies affect overall animal health.

  8. Profilaxia e tratamento do edema macular cistoide após cirurgia de catarata

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    Pedro C. Carricondo

    2015-04-01

    Full Text Available O edema macular cistoide é uma das principais causas de baixa de visão após cirurgia de catarata. O processo inflamatório parece ser o principal fator causal do edema. São considerados fatores de risco complicações cirúrgicas, doenças retinianas prévias, diabetes, uveítes e uso de colírios de prostaglandinas. O diagnóstico é feito clinicamente, mas a angiografia fluoresceínica e a tomografia de coerência óptica também são ferramentas importantes para detectar o edema e auxiliar no diagnóstico diferencial. Apesar da profilaxia pré-operatória não ter evidência científica, ela é preconizada especialmente nos casos com fatores de risco. O tratamento inicial é realizado com associação de corticoide e anti-inflamatório não hormonais tópicos. Os casos crônicos e refratários têm diversas alternativas de tratamento, sendo o uso de triancinolona e antiangiogênicos intravítreos as mais utilizadas. Este artigo se propõe a discutir diversos aspectos do edema macular cistoide pseudofácico.

  9. [Inhibition of lactation with lisuride. CLinical evaluation].

    Science.gov (United States)

    Sereno Coló, J A; Navarrete Horta, M T

    1994-01-01

    Lactation in humans requires the collaboration of neural and endocrine systems. During pregnancy and after parturition prolactin and also sex steroids, corticoids, growth hormone and human placental lactogen are necessary for lactogenesis. In an open, simple and prospective study, 50 women with normal delivery or cesarean section, between 34 and 41 weeks of gestation, were treated with lisuride, 0.2 mg t.i.d. for 14 days in order to inhibit lactation. The arrest of lactation was mandatory for medical reasons and the results were evaluated by changes in breast related with shape, volume, symmetry, coloring, temperature, turgescence, venous appearance, nipple condition, colostrum and lymph nodes increase. Lactation that was already present in 87% of patients in the first exploration 24 hours after delivery was satisfactorily suppressed and also breast pain, engorgement and discomfort caused by milk leakage. None had rebound lactation. 5 patients had light nausea. The dopamine agonist lisuride can be used for primary arrest of lactation with clinical effectiveness and without potential dangerous side effects of hormonal compounds.

  10. Plasmapheresis-induced Clinical Improvement in a Patient with Steroid-Resistant Nephrotic Syndrome Due to Podocin (NPHS2 Gene Station

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    Sylva Skálová

    2010-01-01

    Full Text Available Podocin mutations (NPHS2 gene are mostly responsible for steroid-resistant nephrotic syndrome (SRNS of childhood onset. Patients with NPHS2 gene mutations do not respond to corticoids and other immunosuppressive agents; partial remission can be rarely induced by cyclosporin A. We present a boy, where SRNS was diagnosed within first year of life. By the age of 15 years, proteinuria reached 9000 mg/24 h, cholesterolemia 15 mmol/L, albuminemia 19.6 g/L, in spite of combined therapy with cyclosporine A, methylprednisolone, enalapril and losartan. At that time a combined heterozygous form of two NPHS2 gene mutations (p.R138Q and p.V290M was diagnosed, methylprednisolone was discontinued and patient underwent ten plasmapheresis procedures. This resulted in clinical improvement (proteinuria 3000 mg/24 h, S-cholesterol 6 mmol/L, albumin 30g/L lasting for three years. In conclusion, plasmapheresis can result in clinical improvement and stabilization of SRNS caused by podocine mutation, before renal replacement therapy is initiated.

  11. The roles of noradrenergic and glucocorticoid activation in the development of intrusive memories.

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    Richard A Bryant

    Full Text Available Intrusive memories are a common feature of many psychological disorders. Recent evidence has potentially extended cognitive models of intrusions by identifying the role of biological markers of arousal at the time of consolidation in subsequent memory for emotional events. This study investigated the role of arousal during consolidation in the development of intrusive memories. Seventy-eight university students (37 men and 41 women viewed 20 negative and 20 neutral images. Half the participants then underwent a cold pressor test (High Stress, immersing their hand in ice water, while the remaining participants immersed their hand in warm water (Low Stress. Samples of salivary alpha-amylase (sAA and cortisol were collected from participants at baseline and following the stressor challenge. Participants completed a delayed free recall test and intrusion questionnaires two days later. Participants in the High Stress condition reported more intrusions of negative images than participants in the Low Stress condition. An interaction variable in a linear regression of increased noradrenergic and cortisol values predicted intrusive memories of emotional stimuli for men but not women. These findings are consistent with recent evidence of the combined effects of noradrenaline and corticoid responses to stress on emotional memories, and also with increasing evidence of gender differences in how stress hormones influence formation of emotional memories. These findings point to possible mechanisms by which development of intrusions may be prevented after consolidation of traumatic experiences.

  12. Mielitis transversa relacionada con vacunación anti-influenza A(H1N1

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    María Florencia Arcondo

    2011-04-01

    Full Text Available La mielitis transversa es una enfermedad inflamatoria que se caracteriza por disfunción de la médula espinal. Las causas reconocidas de mielitis transversa son autoinmunes, enfermedades desmielinizantes, post infecciosas y post vacunales, aunque hasta el 50% de los casos son idiopáticas. Las vacunas contra la rubéola, paperas, rabia y gripe estacional han sido asociadas a diversos trastornos neurológicos, como el Síndrome de Guillain Barré, la encefalomielitis diseminada aguda (ADEM y la mielitis transversa. Como mecanismo preventivo luego de la pandemia de 2009, en febrero del año 2010 se inició en nuestro país la campaña de vacunación contra la Influenza A (H1N1. Se presenta el caso de una paciente con hipoestesias que aparecieron cuatro días después de haber recibido la vacuna monovalente anti-influenza A (H1N1 y progresaron con evidente nivel sensitivo. La paciente cumplía criterios diagnósticos de mielitis transversa, según el Transverse Myelitis Consortium Working Group. Tuvo remisión de las imágenes de la resonancia magnética y estabilidad clínica sin tratamiento con corticoides. Se discuten aspectos diagnósticos, pronósticos y terapéuticos de esta entidad clínica.

  13. Inflammatory Response in the Anterior Chamber after Implantation of an Angle-Supported Lens in Phakic Myopic Eyes

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    Suphi Taneri

    2014-01-01

    Full Text Available Purpose. To evaluate the inflammatory reaction after implantation of an angle-supported foldable acrylic anterior chamber IOL for myopia correction over time. Methods. Adult individuals seeking vision correction with stable myopia >7.0 D were included. Exclusion criteria are anterior chamber depth <2.8 mm, insufficient endothelial cell density, other preexisting ocular conditions, and prior eye surgery. Laser flare photometry and slitlamp examination were performed before and up to 1 year after implantation of an AcrySof Cachet IOL (Alcon Laboratories, Forth Worth, TX, USA. Postoperative treatment comprised antibiotic eye-drops for 5 days and nonsteroidal anti-inflammatory eye-drops (NSAIDs for 4 weeks. Results. Average laser flare values of 15 consecutive eyes of 15 patients were 8.3±9.7 preoperatively and 19.0±24.2 (1 day, 24.0±27.5 (1 week, 17.6±13.4 (1 month, 14.9±15.4 (3 months, and 10.0±7.0 (1 year photon counts/ms after implantation, respectively. Slitlamp examination yielded 0 or 1+ cells (SUN classification in every one eye throughout the follow-up period. Conclusion. Results indicate a low maximum inflammatory response and a quick recovery to a long-term safe level. The use of NSAIDs seems sufficient in routine cases, thus avoiding potential drawbacks of using corticoids.

  14. Update on hypertrophic scar treatment

    Science.gov (United States)

    Rabello, Felipe Bettini; Souza, Cleyton Dias; Júnior, Jayme Adriano Farina

    2014-01-01

    Scar formation is a consequence of the wound healing process that occurs when body tissues are damaged by a physical injury. Hypertrophic scar/span>s and keloids are pathological scar/span>s resulting from abnormal responses to trauma and can be itchy and painful, causing serious functional and cosmetic disability. The current review will focus on the definition of hypertrophic scar/span>s, distinguishing them from keloids and on the various methods for treating hypertrophic scarring that have been described in the literature, including treatments with clearly proven efficiency and therapies with doubtful benefits. Numerous methods have been described for the treatment of abnormal scars, but to date, the optimal treatment method has not been established. This review will explore the differences between different types of nonsurgical management of hypertrophic scar/span>s, focusing on the indications, uses, mechanisms of action, associations and efficacies of the following therapies: silicone, pressure garments, onion extract, intralesional corticoid injections and bleomycin. PMID:25141117

  15. Is pentoxifylline effective in alcoholic hepatitis? –First update

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    Gabriel Rada

    2016-07-01

    Full Text Available ACERCA DE LA ACTUALIZACIÓN: Este resumen Epistemonikos (Living FRISBEE: Living FRIendly Summary of the Body of Evidence using Epistemonikos es una actualización del resumen publicado en Junio de 2014. Incorpora una nueva revisión sistemática que identificó un estudio no incluido en las revisiones previas. La incorporación de esta nueva evidencia lleva a cambios sustantivos en la evidencia existente. RESUMEN: La pentoxifilina, un inhibidor del factor de necrosis tumoral oral, se ha planteado como un posible tratamiento para la hepatitis alcohólica. Sin embargo, no está claro si es efectiva o si su adición al tratamiento con corticoides agrega beneficios. Utilizando la base de datos Epistemonikos, la cual es mantenida mediante búsquedas en 30 bases de datos, identificamos tres revisiones sistemáticas que en conjunto incluyen ocho estudios aleatorizados. Realizamos un metanálisis y tablas de resumen de los resultados utilizando el método GRADE. Concluimos que la pentoxifilina probablemente no disminuye la mortalidad en pacientes con hepatitis alcohólica.

  16. Coma mixedematoso y midazolam: Reporte de caso.

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    Miguel Pinto Valdivia

    2008-10-01

    Full Text Available Se reporta el caso de un paciente varón sin antecedente previo de patología tiroidea que ingresó por coma mixedematoso y desarrolló insuficiencia respiratoria después de la administración endovenosa de midazolam. Tenía 55 años de edad, y una enfermedad de dos semanas caracterizado por letargia, debilidad, hiporexia y cefalea. Los análisis de laboratorio mostraron anemia, hiponatremia severa y niveles elevados de transaminasas y creatinquinasa. TSH elevada y T4 y T3 en niveles muy bajos. Se inició tratamiento con levotiroxina, corticoides endovenosos y solución hipertónica de cloruro de sodio. La evolución fue mala, se colocó un catéter venoso central bajo sedación con midazolam endovenoso para monitoreo hemodinámico, luego del cual, el paciente desarrolló insuficiencia respiratoria, mayor compromiso del sensorio y falleció. En pacientes con hipotiroidismo, el metabolismo del midazolam esta alterado y puede causar insuficiencia respiratoria. (Rev Med Hered 2008; 19:171-174.

  17. From isolates to a synthetic laboratory population : maintenance of variability in the nematode Haemonchus contortus

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    Saulai M.

    2000-03-01

    Full Text Available Haemonchus contortus isolates were collected from goats of five locations with different climatic characteristics in Guadeloupe archipelago. They were investigated for morphology, morphometrics and allozyme diversity after passage in immunosuppressed lambs using long acting corticoids. The basic aim of the work was to construct a synthetic strain in laboratory conditions which was representative of the isolates. The isolates were only slightly different although climatic conditions were very different. The resemblance of isolates might be due to the practice of goat exchanges between farms or to their insular origin. However the isolate from a smaller island (Les Saintes was different (mostly on morphometrics from all the others originating from Guadeloupe main island. The first assemblage in laboratory resulting from the installation from a mixture of the five isolates was not very representative, whereas the next generation (synthetic strain resembled all the isolates as shown from allozyme study. Female fecundity and length in established synthetic strain were lower than that recorded in isolates, indicating a decrease in fitness, possibly due to the stability of experimental environment. The representativity of the synthetic strain was good but the strain could still evoluate on further passages and should be evaluated on a large number of generations maintained in laboratory.

  18. Update on Eosinophilic Meningoencephalitis and Its Clinical Relevance

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    Graeff-Teixeira, Carlos; da Silva, Ana Cristina Arámburu; Yoshimura, Kentaro

    2009-01-01

    Summary: Eosinophilic meningoencephalitis is caused by a variety of helminthic infections. These worm-specific infections are named after the causative worm genera, the most common being angiostrongyliasis, gnathostomiasis, toxocariasis, cysticercosis, schistosomiasis, baylisascariasis, and paragonimiasis. Worm parasites enter an organism through ingestion of contaminated water or an intermediate host and can eventually affect the central nervous system (CNS). These infections are potentially serious events leading to sequelae or death, and diagnosis depends on currently limited molecular methods. Identification of parasites in fluids and tissues is rarely possible, while images and clinical examinations do not lead to a definitive diagnosis. Treatment usually requires the concomitant administration of corticoids and anthelminthic drugs, yet new compounds and their extensive and detailed clinical evaluation are much needed. Eosinophilia in fluids may be detected in other infectious and noninfectious conditions, such as neoplastic disease, drug use, and prosthesis reactions. Thus, distinctive identification of eosinophils in fluids is a necessary component in the etiologic diagnosis of CNS infections. PMID:19366917

  19. [Allergic transfusion reactions in a patient with multiple food allergies].

    Science.gov (United States)

    Strobel, E; Schöniger, M; Münz, M; Hiefinger-Schindlbeck, R

    2012-07-01

    A 13-year-old girl with an osteosarcoma was treated by surgery and chemotherapy. During three transfusions of apheresis platelet concentrates allergic reactions occurred, partly in spite of premedication with an antihistamine and a corticoid. As the patient declared to be allergic to some foods, in-vitro tests for allergen-specific IgE antibodies were performed and showed markedly positive results for specific IgE to carrot and celery, less so to hazelnut, peanut and a lot of other food antigens. The donor of one of the unsuitable platelet concentrates remembered when questioned, that he had eaten carrots and chocolate with hazelnuts during the evening before platelet donation. Two washed platelet concentrates were transfused without any problem. Furthermore, transfusions of nine red blood cell concentrates and one unit of virus-inactivated frozen pooled plasma were well tolerated. Patients should be asked for allergies previous to transfusions to be alert to allergic reactions in patients with a positive history of food or drug allergies. If premedication with antihistamines does not prevent severe allergic transfusion reactions, transfusion of washed platelet concentrates and of virus-inactivated frozen pooled plasma can be considered. © Georg Thieme Verlag KG Stuttgart · New York.

  20. Miopatía inflamatoria con compromiso inicial de músculos respiratorios y artritis reumatoidea

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    Martín Hunter

    2014-10-01

    Full Text Available Las miopatías inflamatorias constituyen un grupo heterogéneo de enfermedades musculares adquiridas de presentación subaguda, crónica y a veces aguda. Las entidades clínicas más frecuentes son la dermatomiositis, la polimiositis, la miositis necrotizante autoinmune y la miositis por cuerpos de inclusión. Suelen presentarse con debilidad muscular con predominio proximal y simétrica, pero rara vez comprometen los músculos respiratorios. Presentamos el caso de una mujer de 39 años con miopatía inflamatoria inespecífica que presentó insuficiencia respiratoria secundaria a hipoventilación alveolar por debilidad muscular y requirió asistencia respiratoria mecánica. Respondió favorablemente y de forma rápida tras el tratamiento instaurado con inmunosupresores (corticoides y metotrexato e inmunoglobulina humana endovenosa. Se utilizó ventilación no invasiva como alternativa a la intubación orotraqueal con adecuada tolerancia.