WorldWideScience

Sample records for hand-held gene gun

  1. Biolistic transfection of neuronal cultures using a hand-held gene gun.

    Science.gov (United States)

    O'Brien, John A; Lummis, Sarah C R

    2006-01-01

    Biolistic transfection is a technique in which subcellular-sized particles coated with DNA are accelerated to high velocity to propel them into cells. This method is applicable to tissues, cells and organelles, and can be used for both in vitro and in vivo transformations; with the right equipment, it is simple, rapid and efficient. Here we provide a detailed protocol for biolistic transfection of plasmids into cultured human embryonic kidney (HEK) 293 cells and organotypic brain slices using a hand-held gene gun. There are three major steps: (i) coating microcarriers with DNA, (ii) transferring the microcarriers into a cartridge to make a 'bullet', and (iii) firing the DNA-coated microcarriers into cells using a pulse of helium gas. The method can be readily adapted to other cell types and tissues. The protocol can be completed in 1-2 h.

  2. LIBS system with compact fiber spectrometer, head mounted spectra display and hand held eye-safe erbium glass laser gun

    Science.gov (United States)

    Myers, Michael J.; Myers, John D.; Sarracino, John T.; Hardy, Christopher R.; Guo, Baoping; Christian, Sean M.; Myers, Jeffrey A.; Roth, Franziska; Myers, Abbey G.

    2010-02-01

    LIBS (Laser Induced Breakdown Spectroscopy) systems are capable of real-time chemical analysis with little or no sample preparation. A Q-switched laser is configured such that laser induced plasma is produced on targeted material. Chemical element line spectra are created, collected and analyzed by a fiber spectrometer. Line spectra emission data is instantly viewed on a head mounted display. "Eye-safe" Class I erbium glass lasers provide for insitu LIBS applications without the need for eye-protection goggles. This is due to the fact that Megawatt peak power Q-switched lasers operating in the narrow spectral window between 1.5um and 1.6um are approximately 8000 times more "eye-safe" than other laser devices operating in the UV, visible and near infrared. In this work we construct and demonstrate a LIBS system that includes a hand held eye-safe laser gun. The laser gun is fitted with a micro-integrating sphere in-situ target interface and is designed to facilitate chemical analysis in remote locations. The laser power supply, battery pack, computer controller and spectrophotometer components are packaged into a utility belt. A head mounted display is employed for "hands free" viewing of the emitted line spectra. The system demonstrates that instant qualitative and semi-quantitative chemical analyses may be performed in remote locations utilizing lightweight commercially available system components ergonomically fitted to the operator.

  3. Hand-held medical robots.

    Science.gov (United States)

    Payne, Christopher J; Yang, Guang-Zhong

    2014-08-01

    Medical robots have evolved from autonomous systems to tele-operated platforms and mechanically-grounded, cooperatively-controlled robots. Whilst these approaches have seen both commercial and clinical success, uptake of these robots remains moderate because of their high cost, large physical footprint and long setup times. More recently, researchers have moved toward developing hand-held robots that are completely ungrounded and manipulated by surgeons in free space, in a similar manner to how conventional instruments are handled. These devices provide specific functions that assist the surgeon in accomplishing tasks that are otherwise challenging with manual manipulation. Hand-held robots have the advantages of being compact and easily integrated into the normal surgical workflow since there is typically little or no setup time. Hand-held devices can also have a significantly reduced cost to healthcare providers as they do not necessitate the complex, multi degree-of-freedom linkages that grounded robots require. However, the development of such devices is faced with many technical challenges, including miniaturization, cost and sterility, control stability, inertial and gravity compensation and robust instrument tracking. This review presents the emerging technical trends in hand-held medical robots and future development opportunities for promoting their wider clinical uptake.

  4. Hand-held Dynamo-metry

    OpenAIRE

    Ploeg, Rutger Jan Otto van der

    1992-01-01

    This study describes the application of a hand-held dynamometer that was designed to measure muscle strength in normal individuals and neurological patients in a simple way, comparable to manual muscle testing. Zie: Summary

  5. HAND-HELD MYOMETRY - REFERENCE VALUES

    NARCIS (Netherlands)

    VANDERPLOEG, RJO; FIDLER, [No Value; OOSTERHUIS, HJGH

    1991-01-01

    In thirteen major muscle groups of 50 healthy females and 50 males, aged 20-60 years, maximum voluntary contraction was measured with a hand-held dynamometer. The intrasession variation, the left-right variation, and the fifth and fiftieth centile values were calculated. The ratio of two observation

  6. Interial sensing in a hand held dynamometer

    NARCIS (Netherlands)

    Veltink, Peter H.; Nieuwland, Daniel M.; Harlaar, Jaap; Baten, Chris T.M.

    1996-01-01

    Two methods for kinematic sensing in a hand-held dynamometer using accelerometers and gyroscopes are presented. The first method integrates the angular velocity signal from the gyroscope, after calibration of gyroscope offset and joint angle from a static period immediately preceding each measuremen

  7. High performance hand-held gas chromatograph

    Energy Technology Data Exchange (ETDEWEB)

    Yu, C.M.

    1998-04-28

    The Microtechnology Center of Lawrence Livermore National Laboratory has developed a high performance hand-held, real time detection gas chromatograph (HHGC) by Micro-Electro-Mechanical-System (MEMS) technology. The total weight of this hand-held gas chromatograph is about five lbs., with a physical size of 8{close_quotes} x 5{close_quotes} x 3{close_quotes} including carrier gas and battery. It consumes about 12 watts of electrical power with a response time on the order of one to two minutes. This HHGC has an average effective theoretical plate of about 40k. Presently, its sensitivity is limited by its thermal sensitive detector at PPM. Like a conventional G.C., this HHGC consists mainly of three major components: (1) the sample injector, (2) the column, and (3) the detector with related electronics. The present HHGC injector is a modified version of the conventional injector. Its separation column is fabricated completely on silicon wafers by means of MEMS technology. This separation column has a circular cross section with a diameter of 100 pm. The detector developed for this hand-held GC is a thermal conductivity detector fabricated on a silicon nitride window by MEMS technology. A normal Wheatstone bridge is used. The signal is fed into a PC and displayed through LabView software.

  8. 30 CFR 57.12033 - Hand-held electric tools.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Hand-held electric tools. 57.12033 Section 57.12033 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Surface and Underground § 57.12033 Hand-held electric tools. Hand-held electric tools shall not...

  9. 30 CFR 56.12033 - Hand-held electric tools.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Hand-held electric tools. 56.12033 Section 56.12033 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL....12033 Hand-held electric tools. Hand-held electric tools shall not be operated at high...

  10. Microfluidic MEMS hand-held flow cytometer

    Science.gov (United States)

    Grafton, Meggie M. G.; Maleki, Teimour; Zordan, Michael D.; Reece, Lisa M.; Byrnes, Ron; Jones, Alan; Todd, Paul; Leary, James F.

    2011-02-01

    Due to a number of recent technological advances, a hand-held flow cytometer can be achieved by use of semiconductor illuminators, optical sensors (all battery powered) and sensitive cell markers such as immuno-quantum dot (Qdot) labels. The specific application described is of a handheld blood analyzer that can quickly process a drop of whole, unfractionated human peripheral blood by real-time, on-chip magnetic separation of white blood cells (WBCs) and red blood cells (RBCs) and further fluorescence analysis of Qdot labeled WBC subsets. Various microfluidic patterns were fabricated in PDMS and used to characterize flow of single cells and magnetic deflection of magnetically labeled cells. An LED excitation, avalanche photodiode detection system (SensL Technologies, Ltd., Cork, Ireland) was used for immuno-Qdot detection of WBC subsets. A static optical setup was used to determine the sensitivity of the detection system. In this work we demonstrate: valve-less, on-chip magnetic sorting of immunomagnetically labeled white blood cells, bright Qdot labeling of lymphocytes, and counting of labeled white blood cells. Comparisons of these results with conventional flow cytometric analyses are reported. Sample preparation efficiency was determined by labeling of isolated white blood cells. Appropriate flow rates were determined for optical detection and confirmed with flowing particles. Several enabling technologies required for a truly portable, battery powered, hand-held flow cytometer for use in future point-of-care diagnostic devices have been demonstrated. The combining of these technologies into an integrated handheld instrument is in progress and results on whole blood cell analysis are to be reported in another paper.

  11. Vaccination Using Gene-Gun Technology.

    Science.gov (United States)

    Bergmann-Leitner, Elke S; Leitner, Wolfgang W

    2015-01-01

    DNA vaccines against infection with Plasmodium have been highly successful in rodent models of malaria and have shown promise in the very limited number of clinical trials conducted so far. The vaccine platform is highly attractive for numerous reasons, such as low cost and a very favorable safety profile. Gene gun delivery of DNA plasmids drastically reduces the vaccine dose and does not only have the potential to make vaccines more accessible and affordable, but also simplifies (a) the testing of novel antigens as vaccine candidates, (b) the testing of antigen combinations, and (c) the co-delivery of antigens with molecular adjuvants such as cytokines or costimulatory molecules. Described in this chapter are the preparation of the inoculum (i.e., DNA plasmids attached to gold particles, coating to the inside of plastic tubing also referred to as gene gun "bullets" or cartridges), the gene gun vaccination procedure, and the challenge of mice with Plasmodium berghei parasites to test the efficacy of the experimental vaccine.

  12. Epilepsy Forewarning Using A Hand-Held Device

    Energy Technology Data Exchange (ETDEWEB)

    Hively, LM

    2005-02-21

    Over the last decade, ORNL has developed and patented a novel approach for forewarning of a large variety of machine and biomedical events. The present implementation uses desktop computers to analyze archival data. This report describes the next logical step in this effort, namely use of a hand-held device for the analysis.

  13. 30 CFR 57.7053 - Moving hand-held drills.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Moving hand-held drills. 57.7053 Section 57.7053 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Drilling...

  14. 30 CFR 56.7053 - Moving hand-held drills.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Moving hand-held drills. 56.7053 Section 56.7053 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Drilling and...

  15. Hand-Held Ultrasonic Instrument for Reading Matrix Symbols

    Science.gov (United States)

    Schramm, Harry F.; Kula, John P.; Gurney, John W.; Lior, Ephraim D.

    2008-01-01

    A hand-held instrument that would include an ultrasonic camera has been proposed as an efficient means of reading matrix symbols. The proposed instrument could be operated without mechanical raster scanning. All electronic functions from excitation of ultrasonic pulses through final digital processing for decoding matrix symbols would be performed by dedicated circuitry within the single, compact instrument housing.

  16. Interactive topology optimization on hand-held devices

    DEFF Research Database (Denmark)

    Aage, Niels; Nobel-Jørgensen, Morten; Andreasen, Casper Schousboe

    2013-01-01

    This paper presents an interactive topology optimization application designed for hand-held devices running iOS or Android. The TopOpt app solves the 2D minimum compliance problem with interactive control of load and support positions as well as volume fraction. Thus, it is possible to change......OS devices from the Apple App Store, at Google Play for the Android platform, and a web-version can be run from www.topopt.dtu.dk....

  17. Vibration and impulsivity analysis of hand held olive beaters.

    Science.gov (United States)

    Deboli, Roberto; Calvo, Angela; Preti, Christian

    2016-07-01

    To provide more effective evaluations of hand arm vibration syndromes caused by hand held olive beaters, this study focused on two aspects: the acceleration measured at the tool pole and the analysis of the impulsivity, using the crest factor. The signals were frequency weighted using the weighting curve Wh as described in the ISO 5349-1 standard. The same source signals were also filtered by the Wh-bl filter (ISO/TS 15694), because the weighting filter Wh (unlike the Wh-bl filter) could underestimate the effect of high frequency vibration on vibration-induced finger disorders. Ten (experienced) male operators used three beater models (battery powered) in the real olive harvesting condition. High vibration total values were obtained with values never lower than 20 m(-2). Concerning the crest factor, the values ranged from 5 to more than 22. This work demonstrated that the hand held olive beaters produced high impulsive loads comparable to the industry hand held tools.

  18. Gene gun delivery systems for cancer vaccine approaches.

    Science.gov (United States)

    Aravindaram, Kandan; Yang, Ning Sun

    2009-01-01

    Gene-based immunization with transgenic DNA vectors expressing tumor-associated antigens (TAA), cytokines, or chemokines, alone or in combination, provides an attractive approach to increase the cytotoxic T cell immunity against various cancer diseases. With this consideration, particle-mediated or gene gun technology has been developed as a nonviral method for gene transfer into various mammalian tissues. It has been shown to induce both humoral and cell-mediated immune responses in both small and large experimental animals. A broad range of somatic cell types, including primary cultures and established cell lines, has been successfully transfected ex vivo or in vitro by gene gun technology, either as suspension or adherent cultures. Here, we show that protocols and techniques for use in gene gun-mediated transgene delivery system for skin vaccination against melanoma using tumor-associated antigen (TAA) human gpl00 and reporter gene assays as experimental systems.

  19. Promoting Physical Activity through Hand-Held Computer Technology

    Science.gov (United States)

    King, Abby C.; Ahn, David K.; Oliveira, Brian M.; Atienza, Audie A.; Castro, Cynthia M.; Gardner, Christopher D.

    2009-01-01

    Background Efforts to achieve population-wide increases in walking and similar moderate-intensity physical activities potentially can be enhanced through relevant applications of state-of-the-art interactive communication technologies. Yet few systematic efforts to evaluate the efficacy of hand-held computers and similar devices for enhancing physical activity levels have occurred. The purpose of this first-generation study was to evaluate the efficacy of a hand-held computer (i.e., personal digital assistant [PDA]) for increasing moderate intensity or more vigorous (MOD+) physical activity levels over 8 weeks in mid-life and older adults relative to a standard information control arm. Design Randomized, controlled 8-week experiment. Data were collected in 2005 and analyzed in 2006-2007. Setting/Participants Community-based study of 37 healthy, initially underactive adults aged 50 years and older who were randomized and completed the 8-week study (intervention=19, control=18). Intervention Participants received an instructional session and a PDA programmed to monitor their physical activity levels twice per day and provide daily and weekly individualized feedback, goal setting, and support. Controls received standard, age-appropriate written physical activity educational materials. Main Outcome Measure Physical activity was assessed via the Community Healthy Activities Model Program for Seniors (CHAMPS) questionnaire at baseline and 8 weeks. Results Relative to controls, intervention participants reported significantly greater 8-week mean estimated caloric expenditure levels and minutes per week in MOD+ activity (p<0.04). Satisfaction with the PDA was reasonably high in this largely PDA-naive sample. Conclusions Results from this first-generation study indicate that hand-held computers may be effective tools for increasing initial physical activity levels among underactive adults. PMID:18201644

  20. Promoting physical activity through hand-held computer technology.

    Science.gov (United States)

    King, Abby C; Ahn, David K; Oliveira, Brian M; Atienza, Audie A; Castro, Cynthia M; Gardner, Christopher D

    2008-02-01

    Efforts to achieve population-wide increases in walking and similar moderate-intensity physical activities potentially can be enhanced through relevant applications of state-of-the-art interactive communication technologies. Yet few systematic efforts to evaluate the efficacy of hand-held computers and similar devices for enhancing physical activity levels have occurred. The purpose of this first-generation study was to evaluate the efficacy of a hand-held computer (i.e., personal digital assistant [PDA]) for increasing moderate intensity or more vigorous (MOD+) physical activity levels over 8 weeks in mid-life and older adults relative to a standard information control arm. Randomized, controlled 8-week experiment. Data were collected in 2005 and analyzed in 2006-2007. Community-based study of 37 healthy, initially underactive adults aged 50 years and older who were randomized and completed the 8-week study (intervention=19, control=18). Participants received an instructional session and a PDA programmed to monitor their physical activity levels twice per day and provide daily and weekly individualized feedback, goal setting, and support. Controls received standard, age-appropriate written physical activity educational materials. Physical activity was assessed via the Community Healthy Activities Model Program for Seniors (CHAMPS) questionnaire at baseline and 8 weeks. Relative to controls, intervention participants reported significantly greater 8-week mean estimated caloric expenditure levels and minutes per week in MOD+ activity (pfirst-generation study indicate that hand-held computers may be effective tools for increasing initial physical activity levels among underactive adults.

  1. Adaptive RF front-ends for hand-held applications

    CERN Document Server

    van Bezooijen, Andre; van Roermund, Arthur

    2010-01-01

    The RF front-end - antenna combination is a vital part of a mobile phone because its performance is very relevant to the link quality between hand-set and cellular network base-stations. The RF front-end performance suffers from changes in operating environment, like hand-effects, that are often unpredictable. ""Adaptive RF Front-Ends for Hand-Held Applications"" presents an analysis on the impact of fluctuating environmental parameters. In order to overcome undesired behavior two different adaptive control methods are treated that make RF frond-ends more resilient: adaptive impedance control,

  2. Adaptation of Predictive Models to PDA Hand-Held Devices

    Directory of Open Access Journals (Sweden)

    Lin, Edward J

    2008-01-01

    Full Text Available Prediction models using multiple logistic regression are appearing with increasing frequency in the medical literature. Problems associated with these models include the complexity of computations when applied in their pure form, and lack of availability at the bedside. Personal digital assistant (PDA hand-held devices equipped with spreadsheet software offer the clinician a readily available and easily applied means of applying predictive models at the bedside. The purposes of this article are to briefly review regression as a means of creating predictive models and to describe a method of choosing and adapting logistic regression models to emergency department (ED clinical practice.

  3. Hand-held portable microarray reader for biodetection

    Science.gov (United States)

    Thompson, Deanna Lynn; Coleman, Matthew A; Lane, Stephen M; Matthews, Dennis L; Albala, Joanna; Wachsmann-Hogiu, Sebastian

    2013-04-23

    A hand-held portable microarray reader for biodetection includes a microarray reader engineered to be small enough for portable applications. The invention includes a high-powered light-emitting diode that emits excitation light, an excitation filter positioned to receive the excitation light, a slide, a slide holder assembly for positioning the slide to receive the excitation light from the excitation filter, an emission filter positioned to receive the excitation light from the slide, a lens positioned to receive the excitation light from the emission filter, and a CCD camera positioned to receive the excitation light from the lens.

  4. Hand held instruments for landmine detection: View from radiation dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Akkurt, Hatice [Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831 (United States)], E-mail: akkurth@ornl.gov; Wagner, John; Eckerman, Keith [Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831 (United States)

    2007-08-21

    Hand held instruments have been proposed and widely studied for landmine detection. However, the operator is not included in these design studies. In this paper, the dose rate received by an operator of a hand held instrument for landmine detection is analyzed using a computational phantom model with Monte Carlo simulations for different source types and source-to-operator distances. The analysis is performed for bare and shielded sources in order to assess the impact of shielding on the operator dose. Additionally, the impact of having soil with varying moisture content has also been investigated. The analysis results, based on Monte Carlo simulations, showed that in addition to source properties, energy, shielding, and source-to-operator distance, the dose received by the operator also depends on soil characteristics. Furthermore, although the effective dose decreases as a function of source-to-operator distance, the absorbed and equivalent dose to some organs at radiogenic risk; e.g. the lungs, thyroid, and stomach, increases with source-to-operator distances, up to 125 cm.

  5. Bone age maturity assessment using hand-held device

    Science.gov (United States)

    Ratib, Osman M.; Gilsanz, Vicente; Liu, Xiaodong; Boechat, M. I.

    2004-04-01

    Purpose: Assessment of bone maturity is traditionally performed through visual comparison of hand and wrist radiograph with existing reference images in textbooks. Our goal was to develop a digital index based on idealized hand Xray images that can be incorporated in a hand held computer and used for visual assessment of bone age for patients. Material and methods: Due to the large variability in bone maturation in normals, we generated a set of "ideal" images obtained by computer combinations of images from our normal reference data sets. Software for hand-held PDA devices was developed for easy navigation through the set of images and visual selection of matching images. A formula based on our statistical analysis provides the standard deviation from normal based on the chronological age of the patient. The accuracy of the program was compared to traditional interpretation by two radiologists in a double blind reading of 200 normal Caucasian children (100 boys, 100 girls). Results: Strong correlations were present between chronological age and bone age (r > 0.9) with no statistical difference between the digital and traditional assessment methods. Determinations of carpal bone maturity in adolescents was slightly more accurate using the digital system. The users did praise the convenience and effectiveness of the digital Palm Index in clinical practice. Conclusion: An idealized digital Palm Bone Age Index provides a convenient and effective alternative to conventional atlases for the assessment of skeletal maturity.

  6. 78 FR 27441 - NIJ Evaluation of Hand-Held Cell Phone Detector Devices

    Science.gov (United States)

    2013-05-10

    ... of Justice Programs NIJ Evaluation of Hand-Held Cell Phone Detector Devices AGENCY: National...) is soliciting interest in supplying hand-held cell phone detector devices for participation in an... soliciting interest in supplying hand-held cell phone detector devices for participation in an evaluation...

  7. 47 CFR 15.519 - Technical requirements for hand held UWB systems.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Technical requirements for hand held UWB... DEVICES Ultra-Wideband Operation § 15.519 Technical requirements for hand held UWB systems. (a) UWB devices operating under the provisions of this section must be hand held, i.e., they are relatively...

  8. Hand-held spectrophotometer design for textile fabrics

    Science.gov (United States)

    Böcekçi, Veysel Gökhan; Yıldız, Kazım

    2017-09-01

    In this study, a hand-held spectrophotometer was designed by taking advantage of the developments in modern optoelectronic technology. Spectrophotometer devices are used to determine the color information from the optic properties of the materials. As an alternative to a desktop spectrophotometer device we have implemented, it is the first prototype, low cost and portable. The prototype model designed for the textile industry can detect the color tone of any fabric. The prototype model consists of optic sensor, processor, display floors. According to the color applied on the optic sensor, it produces special frequency information on its output at that color value. In Arduino type processor, the frequency information is evaluated by the program we have written and the color tone information between 0-255 ton is decided and displayed on the screen.

  9. Comparative Geometrical Investigations of Hand-Held Scanning Systems

    Science.gov (United States)

    Kersten, T. P.; Przybilla, H.-J.; Lindstaedt, M.; Tschirschwitz, F.; Misgaiski-Hass, M.

    2016-06-01

    An increasing number of hand-held scanning systems by different manufacturers are becoming available on the market. However, their geometrical performance is little-known to many users. Therefore the Laboratory for Photogrammetry & Laser Scanning of the HafenCity University Hamburg has carried out geometrical accuracy tests with the following systems in co-operation with the Bochum University of Applied Sciences (Laboratory for Photogrammetry) as well as the Humboldt University in Berlin (Institute for Computer Science): DOTProduct DPI-7, Artec Spider, Mantis Vision F5 SR, Kinect v1 + v2, Structure Sensor and Google's Project Tango. In the framework of these comparative investigations geometrically stable reference bodies were used. The appropriate reference data were acquired by measurement with two structured light projection systems (AICON smartSCAN and GOM ATOS I 2M). The comprehensive test results of the different test scenarios are presented and critically discussed in this contribution.

  10. Hand-Held Devices Detect Explosives and Chemical Agents

    Science.gov (United States)

    2010-01-01

    Ion Applications Inc., of West Palm Beach, Florida, partnered with Ames Research Center through Small Business Innovation Research (SBIR) agreements to develop a miniature version ion mobility spectrometer (IMS). While NASA was interested in the instrument for detecting chemicals during exploration of distant planets, moons, and comets, the company has incorporated the technology into a commercial hand-held IMS device for use by the military and other public safety organizations. Capable of detecting and identifying molecules with part-per-billion sensitivity, the technology now provides soldiers with portable explosives and chemical warfare agent detection. The device is also being adapted for detecting drugs and is employed in industrial processes such as semiconductor manufacturing.

  11. [Intraoperative Measurement of Refraction with a Hand-Held Autorefractometer].

    Science.gov (United States)

    Gesser, C; Küper, T; Richard, G; Hassenstein, A

    2015-07-01

    The aim of this study was to evaluate an intraoperative measurement of objective refraction with a hand-held retinomax instrument. At the end of cataract surgery objective refraction in a lying position was measured with a retinomax instrument. On the first postoperative day the same measurement was performed with a retinomax and a standard autorefractometer. To evaluate the differences between measurements, the spherical equivalent (SE) and Jackson's cross cylinder at 0° (J0) and 45° (J45) was used. 103 eyes were included. 95 of them had normal cataract surgery. Differences between retinomax at the operative day and the standard autorefractometer were 0.68 ± 2.58 D in SE, 0.05 ± 1.4D in J0 and 0.05 ± 1.4D in J45. There were no statistically significant differences between the groups. Intraoperative measurement of the refraction with a retinomax can predict the postoperative refraction. Nevertheless, in a few patients great differences may occur. Georg Thieme Verlag KG Stuttgart · New York.

  12. Hand-held metal detector identification of ingested foreign bodies.

    Science.gov (United States)

    Sacchetti, A; Carraccio, C; Lichenstein, R

    1994-08-01

    The study purpose was to determine the ability of hand-held metal detectors (HHMDs) to identify the presence of ingested metallic foreign bodies (MFBs). Twenty-three children presenting to the emergency department with a complaint of MFBs ingested were enrolled. Sixteen of 23 patients had radiographically proven foreign bodies. The MFBs comprised coins (n = 11), a button battery (n = 1), a medallion (n = 1), a token (n = 1), a needle (n = 1), and a marble (leaded glass) (n = 1). The HHMD correctly detected 15 of 16 radiographically positive MFBs (93%) and correctly excluded a potential MFB in six of six radiographically negative cases. The only foreign body not detected was an ingested needle. One radiograph was equivocal. Radiographic localization of the ingested objects was as follows: esophagus, n = 4; stomach, n = 9; and intestines, n = 3. The HHMD correctly localized all detected MFBs. The HHMD had a sensitivity of 94%, a specificity of 100%, a positive predictive value of 100%, and a negative predictive value of 86%. HHMDs are effective screening devices for possible ingested MFBs. Positive studies localized to the stomach and lower gastrointestinal tract do not require confirmatory radiographic studies.

  13. Cordless hand-held optical 3D sensor

    Science.gov (United States)

    Munkelt, Christoph; Bräuer-Burchardt, Christian; Kühmstedt, Peter; Schmidt, Ingo; Notni, Gunther

    2007-07-01

    A new mobile optical 3D measurement system using phase correlation based fringe projection technique will be presented. The sensor consist of a digital projection unit and two cameras in a stereo arrangement, whereby both are battery powered. The data transfer to a base station will be done via WLAN. This gives the possibility to use the system in complicate, remote measurement situations, which are typical in archaeology and architecture. In the measurement procedure the sensor will be hand-held by the user, illuminating the object with a sequence of less than 10 fringe patterns, within a time below 200 ms. This short sequence duration was achieved by a new approach, which combines the epipolar constraint with robust phase correlation utilizing a pre-calibrated sensor head, containing two cameras and a digital fringe projector. Furthermore, the system can be utilized to acquire the all around shape of objects by using the phasogrammetric approach with virtual land marks introduced by the authors 1, 2. This way no matching procedures or markers are necessary for the registration of multiple views, which makes the system very flexible in accomplishing different measurement tasks. The realized measurement field is approx. 100 mm up to 400 mm in diameter. The mobile character makes the measurement system useful for a wide range of applications in arts, architecture, archaeology and criminology, which will be shown in the paper.

  14. Portable Hand-Held Electrochemical Sensor for the Transuranics

    Energy Technology Data Exchange (ETDEWEB)

    Dale D. Russell, William B. Knowlton, Ph.D.; Russel Hertzog, Ph.D

    2005-11-25

    sensitive detector for uranium. Millimeter scale electrodes, operated by a hand-held instrument assembled in this lab and operated in the voltammetric mode, were transported to the DOE-Nevada test site (Las Vegas, NV) where field detection and quantitation of plutonium, uranium, and a mixture of these two elements was also demonstrated. Several probe designs were prepared, built and tested including probes with movable protective windows. A miniature, battery powered potentiostat was designed, built and demonstrated for use in a hand-held field portable instrument. This work was performed largely by undergraduates who gained valuable research experience, and many of them have continued on to graduate schools. In addition, they all gained exposure to and appreciation for national security research, in particular non-proliferation research. Four graduate students participated and one earned the MS degree on this project.

  15. Hand-Held Units for Short-Range Wireless Biotelemetry

    Science.gov (United States)

    Miranda, Felix A.; Simons, Rainee N.

    2008-01-01

    Special-purpose hand-held radiotransceiver units have been proposed as means of short-range radio powering and interrogation of surgically implanted microelectromechanical sensors and actuators. These units are based partly on the same principles as those of the units described in "Printed Multi- Turn Loop Antennas for RF Biotelemetry" (LEW-17879-1), NASA Tech Briefs, Vol. 31, No. 6 (June 2007), page 48. Like the previously reported units, these units would make it unnecessary to have wire connections between the implanted devices and the external equipment used to activate and interrogate them. Like a unit of the previously reported type, a unit of the type now proposed would include a printed-circuit antenna on a dielectric substrate. The antenna circuitry would include integrated surface-mount inductors for impedance tuning. Circuits for processing the signals transmitted and received by the antenna would be included on the substrate. During operation, the unit would be positioned near (but not in electrical contact with) a human subject, in proximity to a microelectromechanical sensor or actuator that has been surgically implanted in the subject. It has been demonstrated that significant electromagnetic coupling with an implanted device could be established at a distance of as much as 4 in. (.10 cm). During operation in the interrogation mode, the antenna of the unit would receive a radio telemetry signal transmitted by the surgically implanted device. The antenna substrate would have dimensions of approximately 3.25 by 3.75 inches (approximately 8.3 by 9.5 cm). The substrate would have a thickness of the order of 30 mils (of the order of a somewhat less than a millimeter). The substrate would be made of low-radiofrequency- loss dielectric material that could be, for example, fused quartz, alumina, or any of a number of commercially available radio-frequency dielectric composite materials. The antenna conductors would typically be made of copper or a

  16. Direction-Sensitive Hand-Held Gamma-Ray Spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Mukhopadhyay, S.

    2012-10-04

    A novel, light-weight, hand-held gamma-ray detector with directional sensitivity is being designed. The detector uses a set of multiple rings around two cylindrical surfaces, which provides precise location of two interaction points on two concentric cylindrical planes, wherefrom the source location can be traced back by back projection and/or Compton imaging technique. The detectors are 2.0 × 2.0 mm europium-doped strontium iodide (SrI2:Eu2+) crystals, whose light output has been measured to exceed 120,000 photons/MeV, making it one of the brightest scintillators in existence. The crystal’s energy resolution, less than 3% at 662 keV, is also excellent, and the response is highly linear over a wide range of gamma-ray energies. The emission of SrI2:Eu2+ is well matched to both photo-multiplier tubes and blue-enhanced silicon photodiodes. The solid-state photomultipliers used in this design (each 2.0 × 2.0 mm) are arrays of active pixel sensors (avalanche photodiodes driven beyond their breakdown voltage in reverse bias); each pixel acts as a binary photon detector, and their summed output is an analog representation of the total photon energy, while the individual pixel accurately defines the point of interaction. A simple back-projection algorithm involving cone-surface mapping is being modeled. The back projection for an event cone is a conical surface defining the possible location of the source. The cone axis is the straight line passing through the first and second interaction points.

  17. A high resolution hand-held focused beam profiler

    Science.gov (United States)

    Zapata-Farfan, J.; Garduño-Mejía, J.; Rosete-Aguilar, M.; Ascanio, G.; Román-Moreno, C. J.

    2017-05-01

    The shape of a beam is important in any laser application and depending on the final implementation, there exists a preferred one which is defined by the irradiance distribution.1 The energy distribution (or laser beam profile) is an important parameter in a focused beam, for instance, in laser cut industry, where the beam shape determines the quality of the cut. In terms of alignment and focusing, the energy distribution also plays an important role since the system must be configured in order to reduce the aberration effects and achieve the highest intensity. Nowadays a beam profiler is used in both industry and research laboratories with the aim to characterize laser beams used in free-space communications, focusing and welding, among other systems. The purpose of the profile analyzers is to know the main parameters of the beam, to control its characteristics as uniformity, shape and beam size as a guide to align the focusing system. In this work is presented a high resolution hand-held and compact design of a beam profiler capable to measure at the focal plane, with covered range from 400 nm to 1000 nm. The detection is reached with a CMOS sensor sized in 3673.6 μm x 2738.4 μm which acquire a snap shot of the previously attenuated focused beam to avoid the sensor damage, the result is an image of beam intensity distribution, which is digitally processed with a RaspberryTMmodule gathering significant parameters such as beam waist, centroid, uniformity and also some aberrations. The profiler resolution is 1.4 μm and was probed and validated in three different focusing systems. The spot sizes measurements were compared with the Foucault knife-edge test.

  18. Accuracy and functionality of hand held wood moisture content meters

    Energy Technology Data Exchange (ETDEWEB)

    Forsen, H.; Tarvainen, V. [VTT Building Technology, Espoo (Finland). Building Materials and Products, Wood Technology

    2000-09-01

    The main task of VTT in this EU project was to test and improve the reliability and performance of moisture content meters. A total of 16 resistance type and 6 capacitance type hand-held moisture meters were included in the test series. Test samples of the most important European species (pine, spruce, birch, oak, beech, alder, larch) were obtained from all over Europe. The total survey included about 2,700 pieces for comparative testing. The test material was conditioned to three different moisture contents (8 - 10%, 12 - 14% and 16 - 18%). The moisture gradients in the test specimens were small due to the long conditioning time lasting at least 1 year. The effects of various factors, such as moisture content, species, and temperature, on the electrical resistance of conditioned wood were studied. In the laboratory tests, the resistance - moisture content curves for different species from different countries were determined using conditioned wood material. The species corrections (resistance curves) are quite similar for different counties. Only the resistance curve for Maritime Pine differs clearly from the other resistance curves for the pine species originating from the different countries. The wood temperature corrections are about 0.1 - 0.15% units/deg C which has to be considered when the moisture content of wood is measured at temperatures other than 20 deg C. The other properties of wood, such as sapwood/heartwood and density, do not have a significant effect on resistance values. There were no significant resistance differences related to the type of electrodes, distances between electrodes, and different measuring direction. The commercial instruments for the determination of wood moisture content were tested with respect to accuracy, reliability and ergonomy. The moisture meters were tested both under laboratory and industrial conditions. Most of the resistance meters show a systematic deviation from the actual moisture content because of incorrect MC

  19. 75 FR 27504 - Substantial Product Hazard List: Hand-Held Hair Dryers

    Science.gov (United States)

    2010-05-17

    ... substantial product hazard.'' B. The Product A hand-held hair dryer is a portable electrical appliance with a..., electrically energized wires across which a fan blows air. These dryers are typically used in bathrooms...

  20. Automated Model To Save Energy In Hand Held Communication Devices During Natural Calamities

    Directory of Open Access Journals (Sweden)

    C.Rajanandhini

    2012-05-01

    Full Text Available In recent years mobile phone communication has become a part of humans life. Although technology advances there is a lack of communication during crisis, to overcome the crisis during natural calamities hand held communication plays vital role to save the life of peoples. This paper proposes ideas to save energy in hand held devices during natural calamities such as flood, earthquake, cyclone, etc. Recharging the batteries of hand held devices is a challenging job due to supply of electric current during that time, the role of service provider in maximizing the energy is much important than the individual role with the advancement of modern technology, the service provider can restrict the service utilisation of the individual such that GPS, GPRS and multimedia facilities of their hand held devices. This paper discusses ways to handle the energy efficiency by the service provider and user.

  1. Surgical guidance system using hand-held probe with accompanying positron coincidence detector

    Energy Technology Data Exchange (ETDEWEB)

    Majewski, Stanislaw; Weisenberger, Andrew G.

    2017-10-10

    A surgical guidance system offering different levels of imaging capability while maintaining the same hand-held convenient small size of light-weight intra-operative probes. The surgical guidance system includes a second detector, typically an imager, located behind the area of surgical interest to form a coincidence guidance system with the hand-held probe. This approach is focused on the detection of positron emitting biomarkers with gamma rays accompanying positron emissions from the radiolabeled nuclei.

  2. Hand-held water fluoride analysis: An accessible caries prevention tool for dental professionals.

    Science.gov (United States)

    Quock, Ryan L; Yank, Stephanie W; Chan, Jarvis T

    2011-01-01

    This study sought to compare the relative accuracy of a commercially available hand-held water fluoride analysis unit with a standard laboratory bench-top fluoride-specific electrode/millivoltmeter apparatus, with the goal of identifying possible practical applications of the hand-held unit for preventive dentistry. The units analyzed identical gravimetrically prepared fluoride solutions ranging from 0.1 to 4.0 ppm. The average difference between the measurements from the hand-held unit and the nominal values of the fluoride solutions was 0.011 ppm (SD = 0.068), and the average difference between the hand-held unit's measurements and the bench-top unit's measurements was 0.030 ppm (SD = 0.115). T-test analysis demonstrated no statistical difference between measurements from the hand-held unit with either the nominal values of the fluoride solutions or the bench-top unit's measurements. Results indicate that the hand-held water fluoride analysis unit has an appropriate level of accuracy for the measurement of fluoride levels in drinking water samples by dental professionals.

  3. Computer implemented method, and apparatus for controlling a hand-held tool

    Science.gov (United States)

    Wagner, Kenneth William (Inventor); Taylor, James Clayton (Inventor)

    1999-01-01

    The invention described here in is a computer-implemented method and apparatus for controlling a hand-held tool. In particular, the control of a hand held tool is for the purpose of controlling the speed of a fastener interface mechanism and the torque applied to fasteners by the fastener interface mechanism of the hand-held tool and monitoring the operating parameters of the tool. The control is embodied in intool software embedded on a processor within the tool which also communicates with remote software. An operator can run the tool, or through the interaction of both software, operate the tool from a remote location, analyze data from a performance history recorded by the tool, and select various torque and speed parameters for each fastener.

  4. Implementation of synthetic aperture imaging on a hand-held device

    DEFF Research Database (Denmark)

    Hemmsen, Martin Christian; Kjeldsen, Thomas; Larsen, Lee;

    2014-01-01

    This paper presents several implementations of Syn- thetic Aperture Sequential Beamforming (SASB) on commer- cially available hand-held devices. The implementations include real-time wireless reception of ultrasound radio frequency sig- nals and GPU processing for B-mode imaging. The proposed...... implementation demonstrates that SASB can be executed in-time for real-time ultrasound imaging. The wireless communication between probe and processing device satisfies the required bandwidth for real-time data transfer with current 802.11ac technology. The implementation is evaluated using four different hand-held...

  5. Hand-Held Model of a Sarcomere to Illustrate the Sliding Filament Mechanism in Muscle Contraction

    Science.gov (United States)

    Jittivadhna, Karnyupha; Ruenwongsa, Pintip; Panijpan, Bhinyo

    2009-01-01

    From our teaching of the contractile unit of the striated muscle, we have found limitations in using textbook illustrations of sarcomere structure and its related dynamic molecular physiological details. A hand-held model of a striated muscle sarcomere made from common items has thus been made by us to enhance students' understanding of the…

  6. Note: A hand-held high-Tc superconducting quantum interference device operating without shielding.

    Science.gov (United States)

    He, D F

    2011-02-01

    By improving the compensation circuit, a hand-held high-Tc rf superconducting quantum interference devices (SQUID) system was developed. It could operate well when moving in unshielded environment. To check the operation, it was used to do eddy-current testing by hand moving the SQUID, and the artificial defect under 6 mm aluminum plate could be successfully detected in shielded environment.

  7. Surgical procedure logging with use of a hand-held computer.

    Science.gov (United States)

    Fischer, Sandra; Lapinsky, Stephen E; Weshler, Jason; Howard, Frazer; Rotstein, Lorne E; Cohen, Zane; Stewart, Thomas E

    2002-10-01

    To evaluate the feasibility of incorporating hand-held computing technology in a surgical residency program, by means of hand-held devices for surgical procedure logging linked through the Internet to a central database. Division of General Surgery, University of Toronto. A survey of general surgery residents. The 69 residents in the general surgery training program received hand-held computers with preinstalled medical programs and a program designed for surgical procedure logging. Procedural data were uploaded via the Internet to a central database. Survey data were collected regarding previous computer use as well as previous procedure logging methods. Utilization of the procedure logging system. After a 5-month pilot period, 38% of surgical residents were using the procedure-logging program successfully and on a regular basis. Program use was higher among more junior trainees. Analysis of the database provided valuable information on individual trainees, hospital programs and supervising surgeons, data that would assist in program development. Hand-held devices can be implemented in a large division of general surgery to provide a reference database and a procedure-logging platform. However, user acceptance is not uniform and continued training and support are necessary to increase acceptance. The procedure database provides important information for optimizing trainees' educational experience.

  8. Hand-Held Model of a Sarcomere to Illustrate the Sliding Filament Mechanism in Muscle Contraction

    Science.gov (United States)

    Jittivadhna, Karnyupha; Ruenwongsa, Pintip; Panijpan, Bhinyo

    2009-01-01

    From our teaching of the contractile unit of the striated muscle, we have found limitations in using textbook illustrations of sarcomere structure and its related dynamic molecular physiological details. A hand-held model of a striated muscle sarcomere made from common items has thus been made by us to enhance students' understanding of the…

  9. Integrating a hand held computer and stethoscope into a fetal monitor.

    Science.gov (United States)

    Soltani, Mitra Ahmad

    2009-02-07

    This article presents procedures for modifying a hand held computer or personal digital assistant (PDA) into a versatile device functioning as an electronic stethoscope for fetal monitoring. Along with functioning as an electronic stethoscope, a PDA can provide a useful information source for a medical trainee. Feedback from medical students, residents and interns suggests the device is well accepted by medical trainees.

  10. Clinical assessment of hip strength using a hand-held dynamometer is reliable

    DEFF Research Database (Denmark)

    Thorborg, K; Petersen, J; Magnusson, S P;

    2010-01-01

    rotation (ER), internal rotation (IR), flexion (FLEX) and extension (EXT) using a hand-held dynamometer. Nine subjects (five males, four females), physically active for at least 2.5 h a week, were included. Twelve standardized isometric strength tests were performed twice with a 1-week interval in between...

  11. Online Responses towards Parental Rearing Styles Regarding Hand-Held Devices

    Science.gov (United States)

    Geng, Gretchen; Disney, Leigh

    2014-01-01

    This article reviewed the literature on parental rearing styles and used responses from an online discussion forum to investigate people's opinions towards parental rearing styles and strategies when children use hand-held devices. Critical discourse analysis (CDA) was used as an analysis method via micro, meso and macro multi-level…

  12. Left ventricular hypertrophy screening using a hand-held ultrasound device

    NARCIS (Netherlands)

    E.C. Vourvouri (Eleni); D. Poldermans (Don); A.F.L. Schinkel (Arend); L.Y. Koroleva; F. Sozzi (Fabiola); G.E. Parharidis; J.J. Bax (Jeroen); J.R.T.C. Roelandt (Jos)

    2002-01-01

    textabstractAIMS: To test the diagnostic potential of a hand-held ultrasound device for screening for left ventricular hypertrophy in a hypertensive population using a standard echocardiographic system as a reference. METHODS: One hundred consecutive hypertensive patients were enro

  13. 75 FR 32803 - Notice of Issuance of Final Determination Concerning a GTX Mobile+ Hand Held Computer

    Science.gov (United States)

    2010-06-09

    ... SECURITY U.S. Customs and Border Protection Notice of Issuance of Final Determination Concerning a GTX Mobile+ Hand Held Computer AGENCY: U.S. Customs and Border Protection, Department of Homeland Security...; (d) security software for the device, (e) Fortress Technologies Secure Client security software;...

  14. Environmentally Benign Energetic Time Delay Compositions: Alternatives for the U.S. Army Hand-Held Signal

    Science.gov (United States)

    2014-07-13

    2014, pp 305-314 305 Environmentally Benign Energetic Time Delay Compositions: Alternatives for the U.S. Army Hand- Held Signal Jay C. Poret...munitions such as hand grenades and signaling devices. For example, U.S. Army hand- held signals (HHS) use a pyrotechnic delay element to properly time...compositions for use in the U.S. Army hand- held signal. The large thermal mass of the HHS delay housing, combined with the long burning time requirement

  15. Hand-held probe based optical imaging system towards breast cancer diagnosis

    Science.gov (United States)

    Ge, Jiajia; Jayachandran, Bhavani; Regalado, Steven; Zhu, Banghe; Godavarty, Anuradha

    2007-02-01

    Near-infrared (NIR) optical imaging is an emerging noninvasive modality for breast cancer diagnosis. However, the currently available optical imaging systems towards tomography studies are limited either by instrument portability, patient comfort, or flexibility to image any given tissue volume. Herein, a hand-held based optical imaging system is developed such that it can possibly overcome some of the above limitations. The unique features of the hand-held optical probe are: (i) to perform simultaneous multiple point illumination and detection, thus decreasing the total imaging time and improving the overall signal strength; (ii) to adapt to the contour of tissue surface, thus decreasing the leakage of excitation and emission signal at contact surface; and (iii) to obtain trans-illumination measurements apart from reflectance measurements, thus improving the depth information. The increased detected signal strength as well as total interrogated tissue volume is demonstrated by simulation studies (i.e. forward model) over a 5×10×10 cc slab phantom. The appropriate number and layout of the source and detection points on the probe head is determined and the hand-held optical probe is developed. A frequency-domain ICCD (intensified charge coupled device) detection system, which allows simultaneous multiple points detection, is developed and coupled to the hand-held probe in order to perform fluorescence-enhanced optical imaging of tissue phantoms. In the future, imaging of homogenous liquid phantoms will be used for the assessment of this hand-held system, followed by extensive imaging studies on different phantoms types under various experimental conditions.

  16. 78 FR 20695 - Walk-Through Metal Detectors and Hand-Held Metal Detectors Test Method Validation

    Science.gov (United States)

    2013-04-05

    ... Office of Justice Programs Walk-Through Metal Detectors and Hand-Held Metal Detectors Test Method... detectors and hand-held metal detectors. In order to ensure that the test methods in the standards are... efforts from testing laboratories. NIJ is also seeking the participation of metal detector...

  17. Modeling movements of a long hand-held tool with effects of moments of inertia.

    Science.gov (United States)

    Lin, Chiuhsiang Joe; Chen, Hung-Jen

    2014-04-01

    The current experiment aimed to investigate the effects of weight position on movement time in target acquisition tasks. Subsequently, a simple mathematical model was developed to describe the movement time with the moments of inertia. Ten right-handed participants conducted continuous Fitts pointing tasks using a laparoscopic instrument as a long hand-held tool. The results showed significant effects of weight position on movement time. Furthermore, an extended Fitts' law model is proposed for the moments of inertia produced by the hand, instrument, and a constant mass in different positions. This predictive model accounted for 63% of the variance in movement time. The predictive model proposed in the present study can be applied not only to estimate movement time given a particular target width, instrument movement amplitude, and weight position of a long hand-held tool but also to standardize movement time and establish training standards.

  18. Hand-held cow horn: Resurgence of an old arm or a potential terrorist weapon

    Directory of Open Access Journals (Sweden)

    Lawal Khalid

    2012-01-01

    Full Text Available A 23 year old man presented with intestinal evisceration from stab injury to the left side of the abdomen with a hand-held cow horn at a local night party. He complained of severe abdominal pain and bleeding at the site of injury. He was hemodynamically stable. At emergency exploration, the eviscerated bowel was viable with no adjacent mesenteric tear. Other intra abdominal organs were normal. The eviscerated bowel was lavaged and reduced into the abdomen through the 7cm anterior abdominal wall laceration. The laceration was repaired and abdomen closed in layers. Post operative recovery was uneventful. The hand-held cow horn can easily be concealed and may pass through security checks undetected. It should be added to the ever increasing list of weapons of small scale terror.

  19. Hand-held cow horn: resurgence of an old arm or apotential terrorist weapon

    Science.gov (United States)

    Khalid, Lawal; Ahmed, Adamu

    2012-01-01

    Abstract: A 23 year old man presented with intestinal evisceration from stab injury to the left side of the abdomen with a hand-held cow horn at a local night party. He complained of severe abdominal pain and bleeding at the site of injury. He was hemodynamically stable. At emergency exploration, the eviscerated bowel was viable with no adjacent mesenteric tear. Other intra abdominal organs were normal. The eviscerated bowel was lavaged and reduced into the abdomen through the 7cm anterior abdominal wall laceration. The laceration was repaired and abdomen closed in layers. Post operative recovery was uneventful. The hand-held cow horn can easily be concealed and may pass through security checks undetected. It should be added to the ever increasing list of weapons of small scale terror. PMID:21502787

  20. Hand-held internet tablets for school-based data collection

    Directory of Open Access Journals (Sweden)

    Merry Sally N

    2008-07-01

    Full Text Available Abstract Background In the last 20 years, researchers have been using computer self-administered questionnaires to gather data on a wide range of adolescent health related behaviours. More recently, researchers collecting data in schools have started to use smaller hand-held computers for their ease of use and portability. The aim of this study is to describe a new technology with wi-fi enabled hand-held internet tablets and to compare adolescent preferences of laptop computers or hand-held internet tablets in administering a youth health and well-being questionnaire in a school setting. Methods A total of 177 students took part in a pilot study of a national youth health and wellbeing survey. Students were randomly assigned to internet tablets or laptops at the start of the survey and were changed to the alternate mode of administration about half-way through the questionnaire. Students at the end of the questionnaire were asked which of the two modes of administration (1 they preferred, (2 was easier to use, (3 was more private and confidential, and (4 was easier to answer truthfully. Results Many students expressed no preference between laptop computers or internet tablets. However, among the students who expressed a preference between laptop computers or internet tablets, the majority of students found the internet tablets more private and confidential (p Conclusion This study demonstrates that using wi-fi enabled hand-held internet tablets is a feasible methodology for school-based surveys especially when asking about sensitive information.

  1. Long-Wavelength 256 x 256 QWIP Hand-Held Camera

    Science.gov (United States)

    Gunapala, S. D.; Liu, J. K.; Sundaram, M.; Bandara, S. V.; Shott, C. A.; Hoelter, T.; Maker, P. D.; Muller, R. E.

    1996-01-01

    In this paper, we discuss the development of very sensitive long wavelength infrared (LWIR) GaAs/Al(x)Ga(l-x)As quantum well infrared photodetectors (QWIPs), fabrication of random reflectors for efficient light coupling, and the demonstration of the first hand-held long-wavelength 256 x 256 QWIP focal plane array camera. Excellent imagery, with a noise equivalent differential temperature (NE Delta T) of 25 mK has been achieved.

  2. Hand-held optical imager (Gen-2): improved instrumentation and target detectability.

    Science.gov (United States)

    Gonzalez, Jean; Decerce, Joseph; Erickson, Sarah J; Martinez, Sergio L; Nunez, Annie; Roman, Manuela; Traub, Barbara; Flores, Cecilia A; Roberts, Seigbeh M; Hernandez, Estrella; Aguirre, Wenceslao; Kiszonas, Richard; Godavarty, Anuradha

    2012-08-01

    Hand-held optical imagers are developed by various researchers towards reflectance-based spectroscopic imaging of breast cancer. Recently, a Gen-1 handheld optical imager was developed with capabilities to perform two-dimensional (2-D) spectroscopic as well as three-dimensional (3-D) tomographic imaging studies. However, the imager was bulky with poor surface contact (~30%) along curved tissues, and limited sensitivity to detect targets consistently. Herein, a Gen-2 hand-held optical imager that overcame the above limitations of the Gen-1 imager has been developed and the instrumentation described. The Gen-2 hand-held imager is less bulky, portable, and has improved surface contact (~86%) on curved tissues. Additionally, the forked probe head design is capable of simultaneous bilateral reflectance imaging of both breast tissues, and also transillumination imaging of a single breast tissue. Experimental studies were performed on tissue phantoms to demonstrate the improved sensitivity in detecting targets using the Gen-2 imager. The improved instrumentation of the Gen-2 imager allowed detection of targets independent of their location with respect to the illumination points, unlike in Gen-1 imager. The developed imager has potential for future clinical breast imaging with enhanced sensitivity, via both reflectance and transillumination imaging.

  3. The reliability and validity of hand-held refractometry water content measures of hydrogel lenses.

    Science.gov (United States)

    Nichols, Jason J; Mitchell, G Lynn; Good, Gregory W

    2003-06-01

    To investigate within- and between-examiner reliability and validity of hand-held refractometry water content measures of hydrogel lenses. Nineteen lenses of various nominal water contents were examined by two examiners on two occasions separated by 1 hour. An Atago N2 hand-held refractometer was used for all water content measures. Lenses were presented in a random order to each examiner by a third party, and examiners were masked to any potential lens identifiers. Intraclass correlation coefficients (ICC), 95% limits of agreement, and Wilcoxon signed rank test were used to characterize the within- and between-examiner reliability and validity of lens water content measures. Within-examiner reliability was excellent (ICC, 0.97; 95% limits of agreement, -3.6% to +5.7%), and the inter-visit mean difference of 1.1 +/- 2.4% was not biased (p = 0.08). Between-examiner reliability was also excellent (ICC, 0.98; 95% limits of agreement, -4.1% to +3.9%). The mean difference between examiners was -0.1 +/- 2.1% (p = 0.83). The mean difference between the nominally reported water content and our water content measures was -2.1 +/- 1.7% (p refractometry and is material dependent. Therefore, investigators may need to account for bias when measuring hydrogel lens water content via hand-held refractometry.

  4. Gen-2 hand-held optical imager towards cancer imaging: reflectance and transillumination phantom studies.

    Science.gov (United States)

    Gonzalez, Jean; Roman, Manuela; Hall, Michael; Godavarty, Anuradha

    2012-01-01

    Hand-held near-infrared (NIR) optical imagers are developed by various researchers towards non-invasive clinical breast imaging. Unlike these existing imagers that can perform only reflectance imaging, a generation-2 (Gen-2) hand-held optical imager has been recently developed to perform both reflectance and transillumination imaging. The unique forked design of the hand-held probe head(s) allows for reflectance imaging (as in ultrasound) and transillumination or compressed imaging (as in X-ray mammography). Phantom studies were performed to demonstrate two-dimensional (2D) target detection via reflectance and transillumination imaging at various target depths (1-5 cm deep) and using simultaneous multiple point illumination approach. It was observed that 0.45 cc targets were detected up to 5 cm deep during transillumination, but limited to 2.5 cm deep during reflectance imaging. Additionally, implementing appropriate data post-processing techniques along with a polynomial fitting approach, to plot 2D surface contours of the detected signal, yields distinct target detectability and localization. The ability of the gen-2 imager to perform both reflectance and transillumination imaging allows its direct comparison to ultrasound and X-ray mammography results, respectively, in future clinical breast imaging studies.

  5. Foreign gene transfer into Chinese shrimps (Penaeus chinensis) with gene gun

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Plasmids pG DNA-RZ1 with a GFP (green fluorescent protein) reporter gene and a ribozyme gene incising penaeid white spot baculovirus (WSBV) were first introduced into the fertilized eggs of Chinese shrimps by gene gun. The treated and control samples of different development stages were observed with a fluorescent microscope. The transient expression of GFP gene was high in nauplius and zoea larvae. Results from RT-PCR and PCR for adults showed that the foreign genes had been transferred into the shrimps and had expressed the corresponding proteins. This work has established a transgenic method for penaeid shrimps, which will set base for the application of genetic engineering breeding into industry.

  6. Bacterial spores as particulate carriers for gene gun delivery of plasmid DNA.

    Science.gov (United States)

    Aps, Luana R M M; Tavares, Milene B; Rozenfeld, Julio H K; Lamy, M Teresa; Ferreira, Luís C S; Diniz, Mariana O

    2016-06-20

    Bacillus subtilis spores represent a suitable platform for the adsorption of proteins, enzymes and viral particles at physiological conditions. In the present work, we demonstrate that purified spores can also adsorb DNA on their surface after treatment with cationic molecules. In addition, we demonstrate that DNA-coated B. subtilis spores can be used as particulate carriers and act as an alternative to gold microparticles for the biolistic (gene gun) administration of plasmid DNA in mice. Gene gun delivery of spores pre-treated with DODAB (dioctadecyldimethylammonium bromide) allowed efficient plasmid DNA absorption and induced protein expression levels similar to those obtained with gold microparticles. More importantly, we demonstrated that a DNA vaccine adsorbed on spores can be loaded into biolistic cartridges and efficiently delivered into mice, which induced specific cellular and antibody responses. Altogether, these data indicate that B. subtilis spores represent a simple and low cost alternative for the in vivo delivery of DNA vaccines by the gene gun technology.

  7. Experimental gene therapy using p21Waf1 gene for esophageal squamous cell carcinoma by gene gun technology.

    Science.gov (United States)

    Tanaka, Yuichi; Fujii, Teruhiko; Yamana, Hideaki; Kato, Seiya; Morimatsu, Minoru; Shirouzu, Kazuo

    2004-10-01

    In our previous study, the proliferation rate of esophageal squamous cell carcinoma cell lines, which poorly expressed p21Waf1, was found to be regulated by p21Waf1 gene transfection using adenovirus vector. In the present study, in order to examine the effect of p21Waf1 gene therapy in esophageal cancer, we used gene gun technology, which proved to be a powerful method to introduce the p21Waf1 gene into esophageal cancer cells. p21Waf1 transfection to KE3 and YES2 cells (weakly expressed p21Waf1 protein cells) showed a high expression of p21Waf1 protein after applying this gene gun technique. In KE3 and YES2 cells, statistical significant growth inhibition was observed after p21Waf1 transfection compared with LacZ transfection (KE3, p=0.0009; YES2, pgun technique significantly inhibited the low basal p21Waf1 expressed esophageal cancer cell growth in vitro and in vivo. Furthermore, p21Waf1 transfection strongly enhanced the effect of 5Fu suggesting that p21Waf1 may prove beneficial in chemotherapy combined with gene therapy using gene gun technology in patients with esophageal cancer who have a low level of p21Waf1 expressed tumor.

  8. A hand-held ultrasound machine vs. conventional ultrasound machine in the bedside assessment of post-liver transplant patients.

    Science.gov (United States)

    Trinquart, Ludovic; Bruno, Onorina; Angeli, Maria Luigia; Belghiti, Jacques; Chatellier, Gilles; Vilgrain, Valérie

    2009-10-01

    The purpose was to assess the diagnostic accuracy of a hand-held Doppler ultrasound (US) machine for the bedside detection of liver and vascular abnormalities after liver transplantation in the intensive care unit. The IRB approved this study, and written informed consent was obtained from all patients or the patient's legal representative. Any liver transplant recipient at our institution who needed a bedside Doppler US examination in the intensive care unit was eligible. Patients underwent routine grey-scale, colour, and spectral Doppler US examinations of the liver with a conventional machine, which was taken as the reference method, and with a hand-held machine on the same day. Examinations followed one another and were performed in a blinded fashion by two radiologists. Over a 4-month period, 24 consecutive patients (16 men, median age 54 years old; 16 cadaveric and 8 living related right liver transplantations) underwent 43 examinations with both conventional and hand-held machines. Image quality and overall satisfaction scores of grey-scale were lower with the hand-held than with the conventional machine. The hand-held was similar to the conventional machine for assessing the patency of portal veins, hepatic veins and the IVC in all patients but one. The hand-held machine failed to detect signals in the right branch of the hepatic artery and in the hilum in two and one cases, respectively. There was no abnormal hepatic arterial flow with the conventional machine in any of the patients, and the results were the same with the hand-held machine. Total examination time was significantly longer with the hand-held machine. The hand-held US machine had a high diagnostic accuracy for both parenchymal and vascular analyses compared with a conventional US machine in the bedside assessment of post-liver transplant patients.

  9. Potential role of a new hand-held miniature gamma camera in performing minimally invasive parathyroidectomy

    Energy Technology Data Exchange (ETDEWEB)

    Ortega, Joaquin; Lledo, Salvador [University of Valencia, Clinic University Hospital, Department of Surgery, Valencia (Spain); Ferrer-Rebolleda, Jose [Clinic University Hospital, Department of Nuclear Medicine, Valencia (Spain); Cassinello, Norberto [Clinic University Hospital, Unit of Endocrinologic and Bariatric Surgery, Valencia (Spain)

    2007-02-15

    Sestamibi scans have increased the use of minimally invasive parathyroidectomy (MIP) to treat primary hyperparathyroidism (PHPT) when caused by a parathyroid single adenoma. The greatest concern for surgeons remains the proper identification of pathological glands in a limited surgical field. We have studied the usefulness of a new hand-held miniature gamma camera (MGC) when used intraoperatively to locate parathyroid adenomas. To our knowledge this is the first report published on this subject in the scientific literature. Five patients with PHPT secondary to a single adenoma, positively diagnosed by preoperative sestamibi scans, underwent a MIP. A gamma probe for radioguided surgery and the new hand-held MGC were used consecutively to locate the pathological glands. This new MGC has a module composed of a high-resolution interchangeable collimator and a CsI(Na) scintillating crystal. It has dimensions of around 15 cm x 8 cm x 9 cm and weighs 1 kg. The intraoperative assay of PTH (ioPTH) was used to confirm the complete resection of pathological tissue. All cases were operated on successfully by a MIP. The ioPTH confirmed the excision of all pathological tissues. The MGC proved its usefulness in all patients, even in a difficult case in which the first attempt with the gamma probe failed. In all cases it offered real-time accurate intraoperative images. The hand-held MGC is a useful instrument in MIP for PHPT. It may be used to complement the standard tools used to date, or may even replace them, at least in selected cases of single adenomas. (orig.)

  10. Sensitive SERS nanotags for use with a hand-held 1064 nm Raman spectrometer

    Science.gov (United States)

    Kearns, Hayleigh; Ali, Fatima; Bedics, Matthew A.; Shand, Neil C.; Faulds, Karen; Detty, Michael R.; Graham, Duncan

    2017-07-01

    This is the first report of the use of a hand-held 1064 nm Raman spectrometer combined with red-shifted surface-enhanced Raman scattering (SERS) nanotags to provide an unprecedented performance in the short-wave infrared (SWIR) region. A library consisting of 17 chalcogenopyrylium nanotags produce extraordinary SERS responses with femtomolar detection limits being obtained using the portable instrument. This is well beyond previous SERS detection limits at this far red-shifted wavelength and opens up new options for SERS sensors in the SWIR region of the electromagnetic spectrum (between 950 and 1700 nm).

  11. Real time OCT-based angiography device with hand-held probe (Conference Presentation)

    Science.gov (United States)

    Moiseev, Alexander A.; Gelikonov, Grigory V.; Ksenofontov, Sergey Y.; Gelikonov, Valentin M.; Matveev, Lev A.; Zaitsev, Vladimir Y.; Matveev, Alexander L.; Sirotkina, Marina A.; Gladkova, Natalia D.; Vitkin, I. Alex

    2017-02-01

    This work is dedicated to development of the OCT system with angiography for everyday clinical use. Two major problems were solved during the development: compensation of specific tissue displacements, induced by contact scanning mode and physiological motion of patients (e.g. respiratory and cardiac motions) and on-line visualization of vessel net, to provide the feedback for system operator. The performance of the resulting OCT-based microangiography device with hand-held probe was evaluated by visualization of vessels nets of volunteers oral mucosa and skin on different locations (hands, face, abdomen etc.). Success-rate more than 90% was demonstrated during the experiments.

  12. Analysis of Information Remaining on Hand Held Devices Offered for Sale on the Second Hand Market

    OpenAIRE

    Andy Jones; Craig Valli; Iain Sutherland

    2008-01-01

    The ownership and use of mobile phones, Personal Digital Assistants and other hand held devices is now ubiquitous both for home and business use. The majority of these devices have a high initial cost, a relatively short period before they become obsolescent and a relatively low second hand value.  As a result of this, when the devices are replaced, there are indications that they tend to be discarded.  As technology has continued to develop, it has led to an increasing diversity in the num...

  13. Hand-Held Dynamometry Isometric Torque Reference Values for Children and Adolescents

    OpenAIRE

    Hébert, Luc J.; Maltais, Désirée B.; Lepage, Céline; Saulnier, Joanne; Crête, Mélanie

    2015-01-01

    Purpose: To establish hand-held dynamometry (HHD) maximal isometric muscle torque (MIT) reference values for children and adolescents who are developing typically. Methods: The MIT of 10 upper and lower limb muscle groups was assessed in 351 Caucasian youth (4 years 2 months to 17 years) using a standardized HHD protocol, previously shown to be feasible, valid, and reliable. Results: The mean MIT and 95% confidence interval of the mean for all muscle groups, for each of the 14 age groups (1 y...

  14. Algorithms for a hand-held miniature x-ray fluorescence analytical instrument

    Energy Technology Data Exchange (ETDEWEB)

    Elam, W.T.; Newman, D.; Ziemba, F. [and others

    1998-12-31

    The purpose of this joint program was to provide technical assistance with the development of a Miniature X-ray Fluorescence (XRF) Analytical Instrument. This new XRF instrument is designed to overcome the weaknesses of spectrometers commercially available at the present time. Currently available XRF spectrometers (for a complete list see reference 1) convert spectral information to sample composition using the influence coefficients technique or the fundamental parameters method. They require either a standard sample with composition relatively close to the unknown or a detailed knowledge of the sample matrix. They also require a highly-trained operator and the results often depend on the capabilities of the operator. In addition, almost all existing field-portable, hand-held instruments use radioactive sources for excitation. Regulatory limits on such sources restrict them such that they can only provide relatively weak excitation. This limits all current hand-held XRF instruments to poor detection limits and/or long data collection times, in addition to the licensing requirements and disposal problems for radioactive sources. The new XRF instrument was developed jointly by Quantrad Sensor, Inc., the Naval Research Laboratory (NRL), and the Department of Energy (DOE). This report describes the analysis algorithms developed by NRL for the new instrument and the software which embodies them.

  15. Smartphone based hand-held quantitative phase microscope using the transport of intensity equation method.

    Science.gov (United States)

    Meng, Xin; Huang, Huachuan; Yan, Keding; Tian, Xiaolin; Yu, Wei; Cui, Haoyang; Kong, Yan; Xue, Liang; Liu, Cheng; Wang, Shouyu

    2016-12-20

    In order to realize high contrast imaging with portable devices for potential mobile healthcare, we demonstrate a hand-held smartphone based quantitative phase microscope using the transport of intensity equation method. With a cost-effective illumination source and compact microscope system, multi-focal images of samples can be captured by the smartphone's camera via manual focusing. Phase retrieval is performed using a self-developed Android application, which calculates sample phases from multi-plane intensities via solving the Poisson equation. We test the portable microscope using a random phase plate with known phases, and to further demonstrate its performance, a red blood cell smear, a Pap smear and monocot root and broad bean epidermis sections are also successfully imaged. Considering its advantages as an accurate, high-contrast, cost-effective and field-portable device, the smartphone based hand-held quantitative phase microscope is a promising tool which can be adopted in the future in remote healthcare and medical diagnosis.

  16. Fluorescence-enhanced imaging using a novel hand-held based optical imager: phantom studies

    Science.gov (United States)

    Ge, Jiajia; Zhu, Banghe; Regalado, Steven; Godavarty, Anuradha

    2008-02-01

    Near-infrared (NIR) optical imaging is an emerging noninvasive modality for breast cancer diagnosis. The currently available optical imaging systems towards tomography studies are limited either by instrument portability, patient comfort, or flexibility to image any given tissue volume. Hence, a novel hand-held probe based gain modulated intensified CCD camera imaging system is developed such that it can possibly overcome some of the above limitations. The unique features of this hand-held probe based optical imaging system are: (i) to perform simultaneous multiple point illumination and detection, thus decreasing the total imaging time and improving overall signal strength; (ii) to adapt to the tissue contours, thus decreasing the light leakage at contact surface; and (iii) to obtain trans-illumination measurements apart from reflectance measurements, thus improving the depth information. Phantom studies are performed to demonstrate the feasibility of performing fluorescence optical imaging under different target depths using cubical phantoms (10×6.5×10 cc). The effect of simultaneous multiple point illumination over sequential single point illumination is demonstrated from experimental phantom studies.

  17. Curvelet filter based prescreener for explosive hazard detection in hand-held ground penetrating radar

    Science.gov (United States)

    White, Julie L.; Anderson, Derek T.; Ball, John E.; Parker, Brian

    2016-05-01

    Explosive hazards, above and below ground, are a serious threat to civilians and soldiers. In an attempt to mitigate these threats, different forms of explosive hazard detection (EHD) exist; e.g., multi-sensor hand-held platforms, downward looking and forward looking vehicle mounted platforms, etc. Robust detection of these threats resides in the processing and fusion of different data from multiple sensing modalities, e.g., radar, infrared, electromagnetic induction (EMI), etc. Herein, we focus on a new energy-based prescreener in hand-held ground penetrating radar (GPR). First, we Curvelet filter B-scan signal data using either Reverse-Reconstruction followed by Enhancement (RRE) or selectivity with respect to wedge information in the Curvelet transform. Next, we aggregate the result of a bank of matched filters and run a size contrast filter with Bhattacharyya distance. Alarms are then combined using weighted mean shift clustering. Results are demonstrated in the context of receiver operating characteristics (ROC) curve performance on data from a U. S. Army test site that contains multiple target and clutter types, burial depths and times of the day.

  18. Sensor-Based Technique for Manually Scanned Hand-Held Optical Coherence Tomography Imaging

    Directory of Open Access Journals (Sweden)

    Paritosh Pande

    2016-01-01

    Full Text Available Hand-held optical coherence tomography (OCT imaging probes offer flexibility to image sites that are otherwise challenging to access. While the majority of hand-held imaging probes utilize galvanometer- or MEMS-scanning mirrors to transversely scan the imaging beam, these probes are commonly limited to lateral fields-of-view (FOV of only a few millimeters. The use of a freehand manually scanned probe can significantly increase the lateral FOV. However, using the traditional fixed-rate triggering scheme for data acquisition in a manually scanned probe results in imaging artifacts due to variations in the scan velocity of the imaging probe. These artifacts result in a structurally inaccurate image of the sample. In this paper, we present a sensor-based manual scanning technique for OCT imaging, where real-time feedback from an optical motion sensor is used to trigger data acquisition. This technique is able to circumvent the problem of motion artifacts during manual scanning by adaptively altering the trigger rate based on the instantaneous scan velocity, enabling OCT imaging over a large lateral FOV. The feasibility of the proposed technique is demonstrated by imaging several biological and nonbiological samples.

  19. Finger tracking for hand-held device interface using profile-matching stereo vision

    Science.gov (United States)

    Chang, Yung-Ping; Lee, Dah-Jye; Moore, Jason; Desai, Alok; Tippetts, Beau

    2013-01-01

    Hundreds of millions of people use hand-held devices frequently and control them by touching the screen with their fingers. If this method of operation is being used by people who are driving, the probability of deaths and accidents occurring substantially increases. With a non-contact control interface, people do not need to touch the screen. As a result, people will not need to pay as much attention to their phones and thus drive more safely than they would otherwise. This interface can be achieved with real-time stereovision. A novel Intensity Profile Shape-Matching Algorithm is able to obtain 3-D information from a pair of stereo images in real time. While this algorithm does have a trade-off between accuracy and processing speed, the result of this algorithm proves the accuracy is sufficient for the practical use of recognizing human poses and finger movement tracking. By choosing an interval of disparity, an object at a certain distance range can be segmented. In other words, we detect the object by its distance to the cameras. The advantage of this profile shape-matching algorithm is that detection of correspondences relies on the shape of profile and not on intensity values, which are subjected to lighting variations. Based on the resulting 3-D information, the movement of fingers in space from a specific distance can be determined. Finger location and movement can then be analyzed for non-contact control of hand-held devices.

  20. RGB-D Hand-Held Ob ject Recognition Based on Heterogeneous Feature Fusion

    Institute of Scientific and Technical Information of China (English)

    吕雄; 蒋树强; 王双

    2015-01-01

    Ob ject recognition has many applications in human-machine interaction and multimedia retrieval. However, due to large intra-class variability and inter-class similarity, accurate recognition relying only on RGB data is still a big challenge. Recently, with the emergence of inexpensive RGB-D devices, this challenge can be better addressed by leveraging additional depth information. A very special yet important case of object recognition is hand-held object recognition, as manipulating objects with hands is common and intuitive in human-human and human-machine interactions. In this paper, we study this problem and introduce an effective framework to address it. This framework first detects and segments the hand-held ob ject by exploiting skeleton information combined with depth information. In the ob ject recognition stage, this work exploits heterogeneous features extracted from different modalities and fuses them to improve the recognition accuracy. In particular, we incorporate handcrafted and deep learned features and study several multi-step fusion variants. Experimental evaluations validate the effectiveness of the proposed method.

  1. Analysis of Information Remaining on Hand Held Devices Offered for Sale on the Second Hand Market

    Directory of Open Access Journals (Sweden)

    Andy Jones

    2008-06-01

    Full Text Available The ownership and use of mobile phones, Personal Digital Assistants and other hand held devices is now ubiquitous both for home and business use. The majority of these devices have a high initial cost, a relatively short period before they become obsolescent and a relatively low second hand value.  As a result of this, when the devices are replaced, there are indications that they tend to be discarded.  As technology has continued to develop, it has led to an increasing diversity in the number and type of devices that are available, and the processing power and the storage capacity of the digital storage in the device. All organisations, whether in the public or private sector increasingly use hand held devices that contain digital media for the storage of information relating to their business, their employees or their customers. Similarly, individual private users increasingly use hand held devices containing digital media for the storage of information relating to their private lives.The research revealed that a significant number of organisations and private users are ignorant or misinformed about the volume and type of information that is stored on the hand held devices and the media on which it is stored.  It is apparent that they have either not considered, or are unaware of, the potential impact of this information becoming available to their competitors or those with criminal intent.This main purpose of this study was to gain an understanding of the volume and type of information that may remain on hand held devices that are offered for sale on the second hand market.  A second aim of the research was to determine the level of damage that could, potentially be caused, if the information that remains on the devices fell into the wrong hands.  The study examined a number of hand held devices that had been obtained from sources in the UK and Australia that ranged from internet auction sites, to private sales and commercial

  2. Transient gene expression in tobacco using Gibson assembly and the Gene Gun.

    Science.gov (United States)

    Mattozzi, Matthew D; Voges, Mathias J; Silver, Pamela A; Way, Jeffrey C

    2014-04-18

    In order to target a single protein to multiple subcellular organelles, plants typically duplicate the relevant genes, and express each gene separately using complex regulatory strategies including differential promoters and/or signal sequences. Metabolic engineers and synthetic biologists interested in targeting enzymes to a particular organelle are faced with a challenge: For a protein that is to be localized to more than one organelle, the engineer must clone the same gene multiple times. This work presents a solution to this strategy: harnessing alternative splicing of mRNA. This technology takes advantage of established chloroplast and peroxisome targeting sequences and combines them into a single mRNA that is alternatively spliced. Some splice variants are sent to the chloroplast, some to the peroxisome, and some to the cytosol. Here the system is designed for multiple-organelle targeting with alternative splicing. In this work, GFP was expected to be expressed in the chloroplast, cytosol, and peroxisome by a series of rationally designed 5' mRNA tags. These tags have the potential to reduce the amount of cloning required when heterologous genes need to be expressed in multiple subcellular organelles. The constructs were designed in previous work(11), and were cloned using Gibson assembly, a ligation independent cloning method that does not require restriction enzymes. The resultant plasmids were introduced into Nicotiana benthamiana epidermal leaf cells with a modified Gene Gun protocol. Finally, transformed leaves were observed with confocal microscopy.

  3. Cost effective spectral sensor solutions for hand held and field applications

    Science.gov (United States)

    Reetz, Edgar; Correns, Martin; Notni, Gunther

    2015-05-01

    Optical spectroscopy is without doubt one of the most important non-contact measurement principles. It is used in a wide range of applications from bio-medical to industrial fields. One recent trend is to miniaturize spectral sensors to address new areas of application. The most common spectral sensor type is based on diffraction gratings, while other types are based on micro mechanical systems (MEMS) or filter technologies. The authors represent the opinion that there is a potentially wide spread field of applications for spectrometers, but the market limits the range of applications since they cannot keep up with targeted cost requirements for consumer products. The present article explains an alternative approach for miniature multichannel spectrometer to enhance robustness for hand held field applications at a cost efficient price point.

  4. A hand-held 3D laser scanning with global positioning system of subvoxel precision

    Energy Technology Data Exchange (ETDEWEB)

    Arias, Nestor [GOM, Departamento de Fisica y Geologia, Universidad de Pamplona (Colombia); Meneses, Nestor; Meneses, Jaime [GOTS-CENM, Escuela de Fisica, UIS, Bucaramanga (Colombia); Gharbi, Tijani, E-mail: nesariher@unipamplona.edu.co [Departement D' Optique, FEMTO-ST, 16 Route de Gray, 25030 Besancon (France)

    2011-01-01

    In this paper we propose a hand-held 3D laser scanner composed of an optical head device to extract 3D local surface information and a stereo vision system with subvoxel precision to measure the position and orientation of the 3D optical head. The optical head is manually scanned over the surface object by the operator. The orientation and position of the 3D optical head is determined by a phase-sensitive method using a 2D regular intensity pattern. This phase reference pattern is rigidly fixed to the optical head and allows their 3D location with subvoxel precision in the observation field of the stereo vision system. The 3D resolution achieved by the stereo vision system is about 33 microns at 1.8 m with an observation field of 60cm x 60cm.

  5. Hand-held tools with complex kinematics are efficiently incorporated into movement planning and online control.

    Science.gov (United States)

    Baugh, Lee A; Hoe, Erica; Flanagan, J Randall

    2012-10-01

    Certain hand-held tools alter the mapping between hand motion and motion of the tool end point that must be controlled in order to perform a task. For example, when using a pool cue, the motion of the cue tip is reversed relative to the hand. Previous studies have shown that the time required to initiate a reaching movement (Fernandez-Ruiz J, Wong W, Armstrong IT, Flanagan JR. Behav Brain Res 219: 8-14, 2011), or correct an ongoing reaching movement (Gritsenko V, Kalaska JF. J Neurophysiol 104: 3084-3104, 2010), is prolonged when the mapping between hand motion and motion of a cursor controlled by the hand is reversed. Here we show that these time costs can be significantly reduced when the reversal is instantiated by a virtual hand-held tool. Participants grasped the near end of a virtual tool, consisting of a rod connecting two circles, and moved the end point to displayed targets. In the reversal condition, the rod translated through, and rotated about, a pivot point such that there was a left-right reversal between hand and end point motion. In the nonreversal control, the tool translated with the hand. As expected, when only the two circles were presented, movement initiation and correction times were much longer in the reversal condition. However, when full vision of the tool was provided, the reaction time cost was almost eliminated. These results indicate that tools with complex kinematics can be efficiently incorporated into sensorimotor control mechanisms used in movement planning and online control.

  6. An integrated portable hand-held analyser for real-time isothermal nucleic acid amplification.

    Science.gov (United States)

    Smith, Matthew C; Steimle, George; Ivanov, Stan; Holly, Mark; Fries, David P

    2007-08-29

    A compact hand-held heated fluorometric instrument for performing real-time isothermal nucleic acid amplification and detection is described. The optoelectronic instrument combines a Printed Circuit Board/Micro Electro Mechanical Systems (PCB/MEMS) reaction detection/chamber containing an integrated resistive heater with attached miniature LED light source and photo-detector and a disposable glass waveguide capillary to enable a mini-fluorometer. The fluorometer is fabricated and assembled in planar geometry, rolled into a tubular format and packaged with custom control electronics to form the hand-held reactor. Positive or negative results for each reaction are displayed to the user using an LED interface. Reaction data is stored in FLASH memory for retrieval via an in-built USB connection. Operating on one disposable 3 V lithium battery >12, 60 min reactions can be performed. Maximum dimensions of the system are 150 mm (h) x 48 mm (d) x 40 mm (w), the total instrument weight (with battery) is 140 g. The system produces comparable results to laboratory instrumentation when performing a real-time nucleic acid sequence-based amplification (NASBA) reaction, and also displayed comparable precision, accuracy and resolution to laboratory-based real-time nucleic acid amplification instrumentation. A good linear response (R2 = 0.948) to fluorescein gradients ranging from 0.5 to 10 microM was also obtained from the instrument indicating that it may be utilized for other fluorometric assays. This instrument enables an inexpensive, compact approach to in-field genetic screening, providing results comparable to laboratory equipment with rapid user feedback as to the status of the reaction.

  7. Comparison of central corneal thickness measured by hand-held and desk-mounted ultrasound pachymeters in glaucoma patients.

    Science.gov (United States)

    Salim, Sarwat; Du, Haiming; Wan, Jim

    2015-07-01

    The purpose of this study was to compare the accuracy and reproducibility of central corneal thickness measured by hand-held and desk-mounted ultrasound pachymeter in glaucoma patients under treatment. Prospective study of 65 glaucoma patients. Central corneal thickness was measured by two ultrasound pachymeters: the hand-held, portable PachPen (Accutome, Lynwood, WA), and the desk-mounted PacScan 300 (Sonomed, Lake Success, NY). The mean ± SD central corneal thickness was 526.5 ± 44.8 µm and 530.0 ± 44.7 µm for the hand-held and desk-mounted pachymeters, respectively (p = 0.15). Linear regression analysis revealed a slope of 0.97 with Pearson correlation coefficient of 0.96. Bland-Altman analysis showed a mean difference of measurements by both pachymeters of 3.22 µm with two standard deviations = 9.51. Both instruments showed high intraobserver correlation: 0.972 for the hand-held pachymeter and 0.993 for the desk-mounted pachymeter. Central corneal thickness measurements were comparable with the use of hand-held and desk-mounted ultrasound units in glaucoma patients with good intraobserver reproducibility.

  8. A new hand-held optical reflectometer to measure enamel erosion: correlation with surface hardness and calcium release.

    Science.gov (United States)

    Carvalho, Thiago Saads; Baumann, Tommy; Lussi, Adrian

    2016-04-28

    In the present study, the surface reflection intensity (SRI) was measured from enamel with different induced erosion degrees using a hand-held pen-size reflectometer (Hand-Held) and a Table-Top reflectometer. To validate the Hand-Held reflectometer, we correlated its optical signals with the change of surface microhardness (SMH), and amount of calcium released from the enamel samples during erosion. We used 124 tooth enamel specimens that were exposed to an erosive challenge of either 1, 2, 4, 6, 8, or 10 minutes. SRI and SMH were measured before and after the erosive challenge and we also measured the amount of calcium released to the citric acid. Relative SRI loss (rSRIloss) and relative SMH loss (rSMHloss) were calculated. rSRIloss from the Hand-Held and the Table-Top reflectometers were similar and significantly correlated to rSMHloss and calcium release. The regression analyses showed a significant association between rSRIloss from both reflectometers and rSMHloss and calcium, showing that both reflectometers can be used to measure erosive demineralization of enamel. The Hand-Held reflectometer is capable of assessing in vitro erosion, correlating to other commonly used methods. It is small, easy to handle and provides fast measurement, being a possible candidate to measure erosion in clinical studies.

  9. Comparative assessment of knee extensor and flexor muscle strength measured using a hand-held vs. isokinetic dynamometer.

    Science.gov (United States)

    Muff, Guillaume; Dufour, Stéphane; Meyer, Alain; Severac, François; Favret, Fabrice; Geny, Bernard; Lecocq, Jehan; Isner-Horobeti, Marie-Eve

    2016-09-01

    [Purpose] To compare measurements of knee extensor and flexor muscle strength performed using a hand-held dynamometer and an isokinetic dynamometer in apparently healthy subjects. [Subjects and Methods] Thirty adult volunteers underwent knee muscle strength evaluation using an isokinetic or a hand-held dynamometer. [Results] Strong positive correlations were found between the 2 methods, with correlation coefficients r ranging from 0.72 (95% confidence interval [CI], 0.48-0.86) to 0.87 (95% CI, 0.75-0.94), depending on the muscle group and the isokinetic evaluation mode. The reproducibility of the hand-held dynamometer findings was good, judged by a coefficient of variation of 3.2-4.2%. However, the correlation between the 2 methods for the assessment of flexor/extensor ratios ranged from -0.04 to 0.46. [Conclusion] Knee extensor and flexor muscle strength recorded with a hand-held dynamometer is reproducible and significantly correlated with the isokinetic values, indicating that this method may in some cases be a useful replacement for isokinetic strength measurement. However, for strength ratio assessment, and when judged against the isokinetic standard, a hand-held dynamometer is not a valid option.

  10. Reliability and validity of standing balance assessment index using a hand-held dynamometer in stroke patients.

    Science.gov (United States)

    Iwamoto, Koji; Yoshio, Masaharu; Takata, Yuichi; Kozuka, Naoki

    2016-11-01

    [Purpose] This study aimed to determine the reliability and validity of our standing balance assessment index using a hand-held dynamometer (the hand-held dynamometer assessment index) in stroke patients. [Subjects and Methods] The participants were 60 stroke patients with impaired standing balance. Intrarater and interrater reliabilities were evaluated employing the intraclass correlation coefficient. Criterion-related validity was evaluated by Spearman's rank correlation coefficient between the HHD assessment index and the functional balance scale. [Results] The intraclass correlation coefficient values obtained ranged from 0.91 to 0.98, and the correlation coefficient with the FBS was 0.83. [Conclusion] Our findings confirmed the reliability and validity of the hand-held dynamometer assessment index in stroke patients.

  11. Simple hand-held metal detectors are an effective means of detecting cardiac pacemakers in the deceased prior to cremation.

    Science.gov (United States)

    Stone, Jason Lyle; Williams, John; Fearn, Lesley

    2010-05-01

    The hazard of undetected cardiac pacemakers exploding in crematoria is well described. This short report describes the use of an affordable hand-held metal detector to detect cardiac pacemakers. Over the course of a year, the metal detector located 100% of cardiac pacemakers in a district general hospital mortuary. A simple model using pigskin and fat is also used to demonstrate the effectiveness in vitro. Commercially purchased hand-held metal detectors should be used in all mortuaries responsible for detection and removal of cardiac pacemakers prior to cremation.

  12. Training food service supervisors using hand-held computers to conduct nutritional screening of institutionalized elderly patients.

    Science.gov (United States)

    Orta, J

    1995-01-01

    Six food service supervisors (FSSs) working in skilled nursing facilities were trained to use a hand-held computer, COMPU-CAL/PRO 5.1, to screen institutionalized elderly patients for selected nutritional variables and to record results in the medical record. The study demonstrates that hand-held computer-assisted nutritional screenings: (1) are readily adaptable to on-going efforts, (2) are useful in identifying potential indicators of poor nutritional status in institutionalized elderly patients, (3) can be taught to FSS in a relatively short time, (4) increase nutritionally relevant variables that can be assessed, and (5) improve the quality of documentation in the medical record.

  13. Protein antigen delivery by gene gun-mediated epidermal antigen incorporation (EAI).

    Science.gov (United States)

    Scheiblhofer, Sandra; Ritter, Uwe; Thalhamer, Josef; Weiss, Richard

    2013-01-01

    The gene gun technology can not only be employed for efficient transfer of gene vaccines into upper layers of the skin, but also for application of protein antigens. As a tissue rich in professional antigen presenting cells, the skin represents an attractive target for immunizations. In this chapter we present a method for delivery of the model antigen ovalbumin into the skin of mice termed epidermal antigen incorporation and describe in detail how antigen-specific proliferation in draining lymph nodes can be followed by flow cytometry.

  14. Hand-Held Instrument Fights Acne, Tops Over-the-Counter Market

    Science.gov (United States)

    2007-01-01

    Tyrell Inc., a Houston-based medical technologies company, was able to access engineering support in redesigning a heating element for a hand-held acne-fighting device through SATOP, NASA's Space Alliance Technology Outreach Program. SATOP put Tyrell in contact with The Boeing Company, which assessed the design and made several major contributions. The product, named Zeno, is now the highest selling over-the-counter medical device for the treatment of acne, and in 2006, Zeno was named the "SATOP Texas, Success Story of the Year." Zeno employs proprietary ClearPoint technology to provide relief of mild to moderate inflammatory acne by delivering a precisely controlled low-level dosage of heat to the blemish, causing the bacteria at the root of more than 90 percent of acne to self-destruct. Within its first year on the market, Zeno was cited by various publications for several awards, including Allure's 2005 "Best of Beauty," Marie Claire's "10 Best Gadgets for Girls," and Popular Science's 2005 "Best of What's New." A variation of the Zeno for use in treating herpetic lesions such as cold sores, by killing the virus that causes them, is currently undergoing FDA trials.

  15. 3D indoor modeling using a hand-held embedded system with multiple laser range scanners

    Science.gov (United States)

    Hu, Shaoxing; Wang, Duhu; Xu, Shike

    2016-10-01

    Accurate three-dimensional perception is a key technology for many engineering applications, including mobile mapping, obstacle detection and virtual reality. In this article, we present a hand-held embedded system designed for constructing 3D representation of structured indoor environments. Different from traditional vehicle-borne mobile mapping methods, the system presented here is capable of efficiently acquiring 3D data while an operator carrying the device traverses through the site. It consists of a simultaneous localization and mapping(SLAM) module, a 3D attitude estimate module and a point cloud processing module. The SLAM is based on a scan matching approach using a modern LIDAR system, and the 3D attitude estimate is generated by a navigation filter using inertial sensors. The hardware comprises three 2D time-flight laser range finders and an inertial measurement unit(IMU). All the sensors are rigidly mounted on a body frame. The algorithms are developed on the frame of robot operating system(ROS). The 3D model is constructed using the point cloud library(PCL). Multiple datasets have shown robust performance of the presented system in indoor scenarios.

  16. Noise surveys of hand-held pneumatic rock drills in Hong Kong.

    Science.gov (United States)

    Tah-Chew, T; Keung, W C

    1991-10-01

    A study of the noise generated by hand-held pneumatic rock drills at 15 road works locations in Hong Kong was conducted in 1989. The locations of road construction works were identified over one week period. Sound pressure levels (SPL) and band frequency analysis were measured with the integrated sound level meter at the level of the operator's ears. The sound levels for all 15 operators exceeded the local statutory limit of 90 dBA. The average sound level was 107.4 dBA and the corresponding continuous equivalent level adjusted to 8 hours or L eq (8h) was 104.8 dBA. The sound levels for the octave frequencies from 125 Hertz to 8000 Hertz were all in excess of 90 dBA. Estimates of the risk of developing hearing impairment for conversation speech among the operators were 18% and 42% after 5 and 10 years of exposure, respectively. Although there is adequate statutory control to restrict and reduce the hazards caused by noise at road construction works to the workers and to the public at large, no noise control measures were noted at the work sites and none of the operators used hearing protection. This situation was compounded by the short-term nature of road works and the high mobility of the operators.

  17. Flexible CMOS low-noise amplifiers for beyond-3G wireless hand-held devices

    Science.gov (United States)

    Becerra-Alvarez, Edwin C.; Sandoval-Ibarra, Federico; de la Rosa, José M.

    2009-05-01

    This paper explores the use of reconfigurable Low-Noise Amplifiers (LNAs) for the implementation of CMOS Radio Frequency (RF) front-ends in the next generation of multi-standard wireless transceivers. Main circuit strategies reported so far for multi-standard LNAs are reviewed and a novel flexible LNA intended for Beyond-3G RF hand-held terminals is presented. The proposed LNA circuit consists of a two-stage topology that combines inductive-source degeneration with PMOS-varactor based tuning network and a programmable load to adapt its performance to different standard specifications without penalizing the circuit noise and with a reduced number of inductors as compared to previous reported reconfigurable LNAs. The circuit has been designed in a 90-nm CMOS technology to cope with the requirements of the GSM, WCDMA, Bluetooth and WLAN (IEEE 802.11b-g) standards. Simulation results, including technology and packaging parasitics, demonstrate correct operation of the circuit for all the standards under study, featuring NF13.3dB and IIP3>10.9dBm, over a 1.85GHz-2.4GHz band, with an adaptive power consumption between 17mW and 22mW from a 1-V supply voltage. Preliminary experimental measurements are included, showing a correct reconfiguration operation within the operation band.

  18. Appearance based key-shot selection for a hand held camera

    Science.gov (United States)

    Alefs, Bram; Dijk, Judith

    2009-05-01

    Automatic selection of key-shots is an important step for video data processing. Depending on the purpose, key-shot selection provides user feed back on recorded data, storage reduction and viewpoint selection and it can be used for panoramic image stitching and 3D-reconstruction. In particular, investigating scenes of crime or accidental investigations involves large amount of data, containing information on physical arrangement of objects, details on surface geometry and appearances. This paper proposes an efficient method for automatic selection of key-shot, providing onsite feedback on recorded segments and automatic selection of view-points for 3D-reconstruction. It uses appearance based object and scene modeling for a freely moving, hand held camera. The camera motion is determined on two levels, comparing appearances of local image regions and full 3D reconstruction. On the lower level, the 2D-warp between subsequent video frames is used to determine local change of image appearance and derive a set of motion key frames. These keyframes than are used to determine full 3D motion and to reconstruct objects. Furthermore, key-frames are used for fast indexation and detection of loop closures. Examples for automatic key-frame selection are given for an re-enacted crime scene, and compared to manual selection.

  19. Guiding brain tumor resection using surface-enhanced Raman scattering nanoparticles and a hand-held Raman scanner.

    Science.gov (United States)

    Karabeber, Hazem; Huang, Ruimin; Iacono, Pasquale; Samii, Jason M; Pitter, Ken; Holland, Eric C; Kircher, Moritz F

    2014-10-28

    The current difficulty in visualizing the true extent of malignant brain tumors during surgical resection represents one of the major reasons for the poor prognosis of brain tumor patients. Here, we evaluated the ability of a hand-held Raman scanner, guided by surface-enhanced Raman scattering (SERS) nanoparticles, to identify the microscopic tumor extent in a genetically engineered RCAS/tv-a glioblastoma mouse model. In a simulated intraoperative scenario, we tested both a static Raman imaging device and a mobile, hand-held Raman scanner. We show that SERS image-guided resection is more accurate than resection using white light visualization alone. Both methods complemented each other, and correlation with histology showed that SERS nanoparticles accurately outlined the extent of the tumors. Importantly, the hand-held Raman probe not only allowed near real-time scanning, but also detected additional microscopic foci of cancer in the resection bed that were not seen on static SERS images and would otherwise have been missed. This technology has a strong potential for clinical translation because it uses inert gold-silica SERS nanoparticles and a hand-held Raman scanner that can guide brain tumor resection in the operating room.

  20. Utility of hand-held echocardiography in outpatient pediatric cardiology management.

    Science.gov (United States)

    Riley, Alan; Sable, Craig; Prasad, Aparna; Spurney, Christopher; Harahsheh, Ashraf; Clauss, Sarah; Colyer, Jessica; Gierdalski, Marcin; Johnson, Ashley; Pearson, Gail D; Rosenthal, Joanna

    2014-12-01

    Adult patient series have shown hand-held echocardiography (echo) units (HHE) to be accurate for rapid diagnosis and triage. This is the first study to evaluate the ability of HHE to inform decision making in outpatient pediatric cardiology. New pediatric cardiology patients in outpatient clinics staffed by six pediatric cardiologists (experience 1-17 years) were prospectively enrolled if an echocardiogram (echo) was ordered during their initial visit. After history and physical examination and before a standard echo, the cardiologists performed a bedside HHE examination (GE Vscan 1.7-3.8 MHz), documented findings, and made a clinical decision. Diagnoses and decisions based on HHE were compared with final management after the standard echo. The study enrolled 101 subjects (ages 9 days to 19 years). The cardiologists considered HHE imaging adequate for decision making for 80 of the 101 subjects. For 77 of the 80 subjects with acceptable HHE imaging (68/68 normal and 9/12 abnormal standard echoes), the HHE-based primary diagnoses and decisions agreed with the final management. The sensitivity of HHE was 75 % (95 % confidence interval [CI] 43-94 %) and the positive predictive value 100 % (95 % CI 66-100 %) for pediatric heart disease. The agreement between standard echocardiography and HHE imaging was substantial (κ = 0.82). Excluding one of the least experienced cardiologists, HHE provided the basis for correct cardiac diagnoses and management for all the subjects with acceptable HHE imaging (58/58 normal and 9/9 abnormal echoes). In outpatient pediatric cardiology, HHE has potential as a tool to complement physical examination. Further investigation is needed to evaluate how value improves with clinical experience.

  1. Consumer product safety: Risk assessment of exposure to asbestos emissions from hand-held hair dryers

    Science.gov (United States)

    Hallenbeck, William H.

    1981-01-01

    The United States Consumer Product Safety Commission (CPSC) is concerned that consumer exposure to asbestos from consumer products may present an unreasonable risk of injury. Recently, CPSC has obtained agreement by industry to cease production and distribution of hair dryers containing asbestos heat insulation. CPSC intends to broaden its investigation by selecting consumer products containing asbestos for “priority attention.” The Commission does not intend to make quantitative estimates of cancer risks posed by exposure to asbestos fibers in making regulatory decisions. This position may lead to a serious waste of resources for the Commission, industry, and society. The Commission should focus its initial attention on those products for which the release of asbestos is significant enough to cause an unreasonable health risk. To make a risk assessment for a particular use of asbestos, CPSC must acquire or request data on asbestos emissions and define “unreasonable risk to health.” In an attempt to give some meaning to the phrase “risk assessment,” the primary goal of this paper is to present a detailed risk assessment of exposure to asbestos from hand-held hair dryers. Several scenarios of use are presented using various assumptions regarding time of operation, mixing of fibers in a small room, rate of fiber emission, and time of exposure. The worst case analysis of the health risk of exposure to hair dryer emissions is based on several conservative assumptions and shows that the increased number of deaths per year due to respiratory cancer is 4 for the entire United States population. A more representative case analysis shows the increased number of deaths to be on the order of 0.15 per year.

  2. Validation of a portable hand-held whole-blood ketone meter for use in cats.

    Science.gov (United States)

    Weingart, Christiane; Lotz, Fabian; Kohn, Barbara

    2012-03-01

    Urinary dipsticks are the most frequent method used for screening of ketones in animals, but this method has many drawbacks. In human medicine, portable meters that measure ketones in whole blood have largely replaced urinary dipsticks. The aim of this prospective study was to validate a portable whole-blood ketone meter for use in cats. Sixty-two cats (11 clinically healthy, 51 with diabetes mellitus) were included in the study. The concentration of β-hydroxybuyrate (β-HB) was measured in venous and capillary blood with a hand-held ketone meter (Precision Xceed; assay range 0-8 mmol/L) and compared with a spectrophotometric method. Precision, accuracy, and the effects of hematocrit and anticoagulants were evaluated. Between-run precision using low- and high-concentration control solutions was 8.1% and 2.6%, respectively; within-run coefficient of variation determined using 12 feline blood samples was 2.8%. In the 62 cats, β-HB concentrations measured with the portable ketone meter ranged from 0-7.4 mmol/L (median 0.9 mmol/L). When β-HB concentrations measured by the portable meter were 4.0 mmol/L were lower than those obtained by the reference method in 20 of 24 cats (83%). There was good correlation between capillary and venous measurements. Results were not affected by hematocrits from 0.17 to 0.50 L/L, but EDTA was not a suitable anticoagulant. Measurement of β-HB concentration in peripheral or capillary blood by an easy-to-use portable ketone meter was suitable for detecting ketonemia in cats. Underestimation of β-HB concentration was observed at higher values, but results were sufficiently high to aid in diagnosing diabetic ketoacidosis. © 2012 American Society for Veterinary Clinical Pathology.

  3. Moving a hand-held object: Reconstruction of referent coordinate and apparent stiffness trajectories.

    Science.gov (United States)

    Ambike, S; Zhou, T; Zatsiorsky, V M; Latash, M L

    2015-07-01

    This study used the framework of the referent configuration hypothesis and slow changes in the external conditions during vertical oscillation of a hand-held object to infer the characteristics of hypothetical control variables. The study had two main objectives: (1) to show that hypothetical control variables, namely, referent coordinates and apparent stiffness of vertical hand position and grip force can be measured in an experiment; and (2) to establish relation(s) between these control variables that yield the classic grip-force-load-force coupling. Healthy subjects gripped a handle and performed vertical oscillations between visual targets at one of five metronome-prescribed frequencies. A HapticMaster robot was used to induce slow changes in the vertical force applied to the handle, while the size of the handle was changed slowly leading to changes in the grip aperture. The subjects were instructed not to react to possible changes in the external forces. A linear, second-order model was used to reconstruct the referent coordinate and apparent stiffness values for each phase of the vertical oscillation cycle using across-cycle regressions. The reconstructed time profiles of the referent coordinates and apparent stiffness showed consistent trends across subjects and movement frequencies. To validate the method, these values were used to predict the vertical force and the grip force applied to the handle for movement cycles that were not utilized in the reconstruction process. Analysis of the coupling between the four variables, two referent coordinates and two apparent stiffness values, revealed a single strong constraint reflecting the coupling between the grip force and vertical force. We view these data as providing experimental support for the idea of controlling natural, multi-muscle actions with shifts in a low-dimensional set of referent coordinates.

  4. Gene gun bombardment-mediated expression and translocation of EGFP-tagged GLUT4 in skeletal muscle fibres in vivo

    DEFF Research Database (Denmark)

    Lauritzen, Hans P M M; Reynet, Christine; Schjerling, Peter

    2002-01-01

    the enhanced green fluorescent protein (EGFP) labelling technique with physical transfection methods in vivo: intramuscular plasmid injection or gene gun bombardment. During optimisation experiments with plasmid coding for the EGFP reporter alone EGFP-positive muscle fibres were counted after collagenase...... treatment of in vivo transfected flexor digitorum brevis (FDB) muscles. In contrast to gene gun bombardment, intramuscular injection produced EGFP expression in only a few fibres. Regardless of the transfection technique, EGFP expression was higher in muscles from 2-week-old rats than in those from 6-week......-old rats and peaked around 1 week after transfection. The gene gun was used subsequently with a plasmid coding for EGFP linked to the C-terminus of GLUT4 (GLUT4-EGFP). Rats were anaesthetised 5 days after transfection and insulin given i.v. with or without accompanying electrical hindleg muscle stimulation...

  5. Gene-gun DNA vaccination aggravates respiratory syncytial virus-induced pneumonitis

    DEFF Research Database (Denmark)

    Bartholdy, Christina; Olszewska, Wieslawa; Stryhn, Anette

    2004-01-01

    elicited with recombinant vaccinia virus expressing the complete RSV M2 protein, but stronger than those induced by a similar DNA construct without the beta2m gene. DNA vaccination led to enhanced pulmonary disease after RSV challenge, with increased weight loss and cell recruitment to the lung. Depletion......A CD8+ T-cell memory response to respiratory syncytial virus (RSV) was generated by using a DNA vaccine construct encoding the dominant Kd-restricted epitope from the viral transcription anti-terminator protein M2 (M2(82-90)), linked covalently to human beta2-microglobulin (beta2m). Cutaneous gene......+ T-cell responses were not induced. Thus, in addition to specific CD8+ T cell-mediated immunopathology, gene-gun DNA vaccination causes non-specific enhancement of RSV disease without affecting virus clearance....

  6. Efficacy of hand held, inexpensive UV light sources on Acanthamoeba, causative organism in amoebic keratitis

    Directory of Open Access Journals (Sweden)

    Ivan Cometa

    2010-01-01

    Full Text Available Ivan Cometa1, Andrew Rogerson1, Scott Schatz21Department of Biology, California State University Fresno, Fresno, CA, USA; 2Arizona College of Optometry, Midwestern University, Glendale, AZ, USAAbstract: Multipurpose lens cleaning solutions (MPS fail to consistently kill or inactivate Acanthamoeba cysts and UV irradiation, while effective at high doses, can damage contact lenses. The present study considered synergy of action between MPS and hand-held inexpensive (ie, relatively weak UV irradiation units. Regardless of disinfection method recently formed cysts (<10 days were far more susceptible to treatment than mature cysts (>14 days. This has important implications for future protocols on testing methods for killing amoebae. The study also showed that cysts of different strains (two tested, FLA2 and P120 are variable in their response to MPS, presumably reflecting differences in cyst wall structure and thus permeability to the disinfectant. On the other hand, the effect of UV irradiation was not wall structure dependent. A 6-hour treatment with MPS alone killed trophic amoebae but failed to kill any mature cysts. Cysts of strain FLA2 were killed after 24 hours with MPS but cysts of strain P120 survived. UV irradiation with the larger 4 W unit killed all cysts after 7 minutes and was more effective than the smaller battery-powered unit (after 10 minutes about 50% of cysts were killed. When the larger unit was used with the MPS disinfection, all trophozoites were killed using UV for 3 minutes and MPS for 1 hour. The resistant P120 cysts remained a challenge but a 2- to 4-minute UV treatment followed by MPS for 3 or 6 hours reduced mature cyst survival by about 50%. The small unit in combination with MPS was less effective but did reduce the time required to kill trophic amoebae in MPS (6 hours MPS alone versus 3 hours MPS with a 1-minute UV treatment. In short, inexpensive UV units do enhance MPS disinfection and future lens cleaning systems

  7. Hand-held analyser based on microchip electrophoresis with contactless conductivity detection for measurement of chemical warfare agent degradation products

    Science.gov (United States)

    Duran, Karolina-Petkovic; Zhu, Yonggang; Chen, Chuanpin; Swallow, Anthony; Stewart, Robert; Hoobin, Pam; Leech, Patrick; Ovenden, Simon

    2008-12-01

    This paper reports on the development of a hand-held device for on-site detection of organophosphonate nerve agent degradation products. This field-deployable analyzer relies on efficient microchip electrophoresis separation of alkyl methylphosphonic acids and their sensitive contactless conductivity detection. Miniaturized, low-powered design is coupled with promising analytical performance for separating the breakdown products of chemical warfare agents such as Soman, Sarin and VX . The detector has a detection limit of about 10 μg/mL and has a good linear response in the range 10-300 μg/mL concentration range. Applicability to environmental samples is demonstrated .The new hand-held analyzer offers great promise for converting conventional ion chromatography or capillary electrophoresis sophisticated systems into a portable forensic laboratory for faster, simpler and more reliable on-site screening.

  8. Rapid prediction of total petroleum hydrocarbons in soil using a hand-held mid-infrared field instrument.

    Science.gov (United States)

    Webster, Grant T; Soriano-Disla, José M; Kirk, Joel; Janik, Leslie J; Forrester, Sean T; McLaughlin, Mike J; Stewart, Richard J

    2016-11-01

    This manuscript reports on the performance of a hand-held diffuse reflectance (mid)-infrared Fourier transform (DRIFT) spectrometer for the prediction of total petroleum hydrocarbons (TPH) in three different diesel-contaminated soils. These soils include: a carbonate dominated clay, a kaolinite dominated clay and a loam from Padova Italy, north Western Australia and southern Nigeria, respectively. Soils were analysed for TPH concentration using a standard laboratory methods and scanned in DRIFT mode with the hand-held spectrometer to determine TPH calibration models. Successful partial least square regression (PLSR) predictions, with coefficient of determination (R(2)) ~0.99 and root mean square error (RMSE) held mid-infrared instrument can accurately detect TPH across different soil types and concentrations, which paves the way for a variety of applications in the field.

  9. An architecture for analysis and collection of RF signals used by hand-held devices in computer communications

    OpenAIRE

    Hwa, Chua Guan

    2001-01-01

    This thesis studies the wireless communications aspects of an Internetconnected hand-held device. It reviews the multipath effects of RF propagation and provides a detailed analysis of the Mobitex network protocols. Field experiments were conducted to measure the signal strength of indoor and outdoor reception. A framework for using real-time wireless communications analysis equipment for the collection of this RF signal is designed and discussed. Expected results from the collection of this ...

  10. Guiding Brain Tumor Resection Using Surface-Enhanced Raman Scattering Nanoparticles and a Hand-Held Raman Scanner

    OpenAIRE

    Karabeber, Hazem; Huang, Ruimin; Iacono, Pasquale; Samii, Jason M.; Pitter, Ken; Holland, Eric C.; Kircher, Moritz F.

    2014-01-01

    The current difficulty in visualizing the true extent of malignant brain tumors during surgical resection represents one of the major reasons for the poor prognosis of brain tumor patients. Here, we evaluated the ability of a hand-held Raman scanner, guided by surface-enhanced Raman scattering (SERS) nanoparticles, to identify the microscopic tumor extent in a genetically engineered RCAS/tv-a glioblastoma mouse model. In a simulated intraoperative scenario, we tested both a static Raman imagi...

  11. In vivo evaluation of a novel, wrist-mounted arterial pressure sensing device versus the traditional hand-held tonometer.

    Science.gov (United States)

    Vardoulis, Orestis; Saponas, T Scott; Morris, Dan; Villar, Nicolas; Smith, Greg; Patel, Shwetak; Tan, Desney

    2016-10-01

    Although hemodynamic parameters can be assessed non-invasively, state-of-the-art non-invasive systems generally require an expert operator and are not applicable for ambulatory measurements. These limitations have restricted our understanding of the continuous behavior of hemodynamic parameters. In this manuscript, we introduce a novel wrist-mounted device that incorporates an array of pressure sensors which can be used to extract arterial waveforms and relevant pulse wave analysis biomarkers. In vivo evaluation is performed with Bland-Altman analysis to compare the novel sensor to a gold-standard hand-held tonometer by assessing their reproducibility and agreement in peripheral augmentation index (AIx) estimation at the radial artery. Arterial waves from 28 randomly selected participants were recorded in a controlled environment. Initially we assess the reproducibility of AIx results for both devices. The intra-class correlation coefficient (ICC) and mean difference ± SD were [0.913, 0.033±0.048] and [0.859, 0.039±0.076] for the hand-held and the wrist-mounted tonometer respectively. We then show that the AIx values derived from the novel tonometer have good agreement, accuracy, and precision when compared against the AIx values derived from the reference hand-held tonometer (ICC 0.927, mean difference 0.026±0.049). In conclusion, we have presented evidence that the new wrist-mounted arterial pressure sensor records arterial waveforms that can be processed to yield AIx values that are in good agreement with its traditional hand-held counterpart.

  12. Gun Play

    Science.gov (United States)

    Mechling, Jay

    2008-01-01

    Biology and the particular gun culture of the United States come together to explain the persistent and powerful attraction of American boys to both real guns and toy guns. The 1990s saw adults begin to conflate "the gun problem" with "the boy problem," sparking attempts (largely failed) to banish toy guns from homes and…

  13. [Experimental gene therapy using p21/WAF1 gene in esophageal squamous cell carcinoma--adenovirus infection and gene gun technology].

    Science.gov (United States)

    Fujii, T; Tanaka, Y; Tanaka, T; Matono, S; Sueyoshi, S; Fujita, H; Shirouzu, K; Kato, S; Yamana, H

    2001-10-01

    p21/WAF1 (p21) inhibits the activity of the cyclin/cdk complex and controls the G1 to S cell phase transition. In the present study, we used a recombinant adenoviral approach and gene gun technology to introduce p21 into esophageal cancer cells in order to assess the effect of p21 on cell growth. Infection with the p21 adenovirus (AdV) using gene gun technology resulted in inhibition of TE9 and KE3 cell growth. The levels of involucrin, which is a marker of squamous epithelium differentiation, markedly increased at 48 h and 72 h after p21 AdV infection in TE9 cells. These results indicate that p21 plays an important role in esophageal cancer cell proliferation. Overexpression of the p21 gene can inhibit cell growth and induce differentiation in esophageal cancer cells. p21 gene therapy may prove beneficial in the treatment of esophageal cancer.

  14. Hand-held personal digital assistant program for the HEMOCHRON RxDx heparin and protamine dosing system.

    Science.gov (United States)

    El Rouby, Soumaya; Rinehart, Kristin; Zucker, Marcia L; LaDuca, Frank M

    2003-09-01

    The use of in vitro dosing assays for heparin and protamine during cardiac surgery has significantly improved overall postoperative patient outcome. The HEMOCHRON RxDx system (International Technidyne Corp, Edison, NJ) is widely used for anticoagulation management. Based on a series of consecutive in vitro tests, the RxDx system is used to quantify the patient's heparin requirement (heparin response test, HRT), measure the activated clotting time (ACT), calculate the blood heparin concentration and the required protamine dose (protamine response test, PRT), as well as determine the efficacy of heparin reversal (protamine dose assay, PDA-O). A hand-held personal digital assistant (PDA) program has been developed that performs the RxDx calculations used for anticoagulation management during cardiac surgery. The Palm m505 hand-held device (Palm, Inc., Santa Clara, CA) is used in concert with any standard Hemochron blood coagulation system. The Palm m505 device has been programmed to perform all the calculations required for the RxDx test system. Patient's body weight, height, and gender are entered into the program using the onscreen keypad and the template provided in the Hemochron program. The calculator automatically provides the patient's blood volume and the recommended heparin dose upon entering the baseline ACT and HRT values and a target ACT. At the end of the case, the optimal protamine dose is determined, and the total heparin level is calculated and displayed upon entry of ACT and PRT clotting times. Following protamine administration, the program calculates any additional protamine required to neutralize residual heparin using the data from a PDA-O test. The RxDx hand-held PDA is accurate, quick, simple, and easy to use, patient data are saved and can be retrieved. The inclusion of this rapid computing technology into the Hemochron RxDx system serves to expand the applications of the Hemochron RxDx system during cardiac interventions.

  15. Comparison of a semiautomated hand-held device to test minimal erythema dose before narrowband ultraviolet B phototherapy with the conventional method using matched doses.

    Science.gov (United States)

    Lynch, M; Carroll, F; Kavanagh, A; Honari, B; Collins, P

    2014-12-01

    A semiautomated hand-held device has been introduced in some phototherapy centres to establish the minimal erythema dose (MED) before treatment with narrowband ultraviolet (NBUV) B. To compare the semiautomated hand-held device with the conventional method of MED testing (a UV-opaque template and a panel of UVB fluorescent tubes), using the same series of incremented doses. Twenty-four patients referred for treatment with NBUVB phototherapy were included. Each patient had MED testing with the conventional method and the semiautomated hand-held device at the same level of the left and right back. The results were read by four investigators each time. The semiautomated hand-held device was a significant estimator of the MED using the conventional panel method (P < 0.001; r = 0.97). The average ratio of the hand-held MED to the conventional MED was 67%. The mean difference between the methods was 165 mJ/cm(2) . The interobserver test showed very high agreement for both methods of MED testing (Cronbach α coefficient 0.97 for the hand-held MED tester vs. 0.93 for the conventional method). The semiautomated hand-held device MED results were lower than that of the conventional panel method and may prolong the treatment course by 2-3 treatments. The hand-held tester is a fast and reproducible method, and may allow more phototherapy units, limited by staff and time, to do MED testing. © 2014 European Academy of Dermatology and Venereology.

  16. Development and Characterization of a Round Hand-Held Silicon Photomultiplier Based Gamma Camera for Intraoperative Imaging

    Science.gov (United States)

    Popovic, Kosta; McKisson, Jack E.; Kross, Brian; Lee, Seungjoon; McKisson, John; Weisenberger, Andrew G.; Proffitt, James; Stolin, Alexander; Majewski, Stan; Williams, Mark B.

    2014-06-01

    This paper describes the development of a hand-held gamma camera for intraoperative surgical guidance that is based on silicon photomultiplier (SiPM) technology. The camera incorporates a cerium doped lanthanum bromide ( LaBr3:Ce) plate scintillator, an array of 80 SiPM photodetectors and a two-layer parallel-hole collimator. The field of view is circular with a 60 mm diameter. The disk-shaped camera housing is 75 mm in diameter, approximately 40.5 mm thick and has a mass of only 1.4 kg, permitting either hand-held or arm-mounted use. All camera components are integrated on a mobile cart that allows easy transport. The camera was developed for use in surgical procedures, including determination of the location and extent of primary carcinomas, detection of secondary lesions, and sentinel lymph node biopsy (SLNB). Here, we describe the camera design and its principal operating characteristics, including spatial resolution, energy resolution, sensitivity uniformity, and geometric linearity. The gamma camera has an intrinsic spatial resolution of 4.2 mm FWHM, an energy resolution of 21.1% FWHM at 140 keV, and a sensitivity of 481 and 73 cps/MBq when using the single- and double-layer collimators, respectively.

  17. Development and characterization of a round hand-held silicon photomultiplier based gamma camera for intraoperative imaging

    Science.gov (United States)

    Popovic, Kosta; McKisson, Jack E.; Kross, Brian; Lee, Seungjoon; McKisson, John; Weisenberger, Andrew G.; Proffitt, James; Stolin, Alexander; Majewski, Stan; Williams, Mark B.

    2017-01-01

    This paper describes the development of a hand-held gamma camera for intraoperative surgical guidance that is based on silicon photomultiplier (SiPM) technology. The camera incorporates a cerium doped lanthanum bromide (LaBr3:Ce) plate scintillator, an array of 80 SiPM photodetectors and a two-layer parallel-hole collimator. The field of view is circular with a 60 mm diameter. The disk-shaped camera housing is 75 mm in diameter, approximately 40.5 mm thick and has a mass of only 1.4 kg, permitting either hand-held or arm-mounted use. All camera components are integrated on a mobile cart that allows easy transport. The camera was developed for use in surgical procedures including determination of the location and extent of primary carcinomas, detection of secondary lesions and sentinel lymph node biopsy (SLNB). Here we describe the camera design and its principal operating characteristics, including spatial resolution, energy resolution, sensitivity uniformity, and geometric linearity. The gamma camera has an intrinsic spatial resolution of 4.2 mm FWHM, an energy resolution of 21.1 % FWHM at 140 keV, and a sensitivity of 481 and 73 cps/MBq when using the single- and double-layer collimators, respectively. PMID:28286345

  18. Development and performance of a hand-held CZT detector for in-situ measurements at the emergency response

    Energy Technology Data Exchange (ETDEWEB)

    Ji, Young Yong; Chung, Kun Ho; Kim, Chang Jong; Lee, Wan No; Choi, Geun Sik; Kang, Mun Ja [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Yoon, Jin [SI Detection Co. Ltd, Daejeon (Korea, Republic of)

    2016-06-15

    A hand-held detector for an emergency response was developed for nuclide identification and to estimate the information of the ambient dose rate in the scene of an accident as well as the radioactivity of the contaminants. To achieve this, the most suitable sensor was first selected as a cadmium zinc telluride (CZT) semiconductor and the signal processing unit from a sensor and the signal discrimination and storage unit were successfully manufactured on a printed circuit board. The performance of the developed signal processing unit was then evaluated to have an energy resolution of about 14 keV at 662 keV. The system control unit was also designed to operate the CZT detector, monitor the detector, battery, and interface status, and check and transmit the measured results of the ambient dose rate and radioactivity. In addition, a collimator, which can control the inner radius, and the airborne dust sampler, which consists of an air filter and charcoal filter, were developed and mounted to the developed CZT detector for the quick and efficient response of a nuclear accident. The hand-held CZT detector was developed to make the in-situ gamma-ray spectrometry and its performance was checked to have a good energy resolution. In addition, the collimator and the airborne dust sampler were developed and mounted to the developed CZT detector for a quick and efficient response to a nuclear accident.

  19. A new hand-held microfluidic cytometer for evaluating irradiation damage by analysis of the damaged cells distribution

    Science.gov (United States)

    Wang, Junsheng; Fan, Zhiqiang; Zhao, Yile; Song, Younan; Chu, Hui; Song, Wendong; Song, Yongxin; Pan, Xinxiang; Sun, Yeqing; Li, Dongqing

    2016-03-01

    Space radiation brings uneven damages to cells. The detection of the distribution of cell damage plays a very important role in radiation medicine and the related research. In this paper, a new hand-held microfluidic flow cytometer was developed to evaluate the degree of radiation damage of cells. The device we propose overcomes the shortcomings (e.g., large volume and high cost) of commercial flow cytometers and can evaluate the radiation damage of cells accurately and quickly with potential for onsite applications. The distribution of radiation-damaged cells is analyzed by a simultaneous detection of immunofluorescence intensity of γ-H2AX and resistance pulse sensor (RPS) signal. The γ-H2AX fluorescence intensity provides information of the degree of radiation damage in cells. The ratio of the number of cells with γ-H2AX fluorescence signals to the total numbers of cells detected by RPS indicates the percentage of the cells that are damaged by radiation. The comparison experiment between the developed hand-held microfluidic flow cytometer and a commercial confocal microscope indicates a consistent and comparable detection performance.

  20. Analysis of accuracy in pointing with redundant hand-held tools: a geometric approach to the uncontrolled manifold method.

    Science.gov (United States)

    Campolo, Domenico; Widjaja, Ferdinan; Xu, Hong; Ang, Wei Tech; Burdet, Etienne

    2013-04-01

    This work introduces a coordinate-independent method to analyse movement variability of tasks performed with hand-held tools, such as a pen or a surgical scalpel. We extend the classical uncontrolled manifold (UCM) approach by exploiting the geometry of rigid body motions, used to describe tool configurations. In particular, we analyse variability during a static pointing task with a hand-held tool, where subjects are asked to keep the tool tip in steady contact with another object. In this case the tool is redundant with respect to the task, as subjects control position/orientation of the tool, i.e. 6 degrees-of-freedom (dof), to maintain the tool tip position (3dof) steady. To test the new method, subjects performed a pointing task with and without arm support. The additional dof introduced in the unsupported condition, injecting more variability into the system, represented a resource to minimise variability in the task space via coordinated motion. The results show that all of the seven subjects channeled more variability along directions not directly affecting the task (UCM), consistent with previous literature but now shown in a coordinate-independent way. Variability in the unsupported condition was only slightly larger at the endpoint but much larger in the UCM.

  1. CT-guided bone biopsy: Initial experience with a commercially available hand held Black and Decker{sup TM} drill

    Energy Technology Data Exchange (ETDEWEB)

    Buckley, O. [Department of Radiology, Adelaide and Meath, Hospital, Tallaght, Dublin 24 (Ireland); Benfayed, W. [Department of Radiology, Adelaide and Meath, Hospital, Tallaght, Dublin 24 (Ireland); Geoghegan, T. [Department of Radiology, Adelaide and Meath, Hospital, Tallaght, Dublin 24 (Ireland); Al-Ismail, K. [Department of Radiology, King Faisal Hospital (Saudi Arabia); Munk, P.L. [Department of Radiology, Musculo-Skeletal division, Vancouver General Hospital, 899 W. 12th Ave., Vancouver, BC V5Z 1M9 (Canada); Torreggiani, William C. [Department of Radiology, Adelaide and Meath, Hospital, Tallaght, Dublin 24 (Ireland)]. E-mail: william.torreggiani@amnch.ie

    2007-01-15

    Purpose: To describe the use of a simple commercially available Black and Decker{sup TM} hand based drill in performing CT-guided bone biopsies. Materials and methods: Three international institutions were enrolled in the study. In each centre, a fellowship trained musculoskeletal radiologist directed the assessment of a hand based commercial drill for performing CT-guided bone biopsies. A specially designed component was engineered which allowed the connection of a standard bone biopsy set to a commercial drill. The component was distributed to the three centres involved. Over a 3-year period, data from all three institutions was collected. Information regarding technical success, diagnostic data and complication rates were all collated to assess the technical feasibility of this technique. Results: In total 68 patients underwent bone biopsy using a hand held commercial drill. Technical success was achieved in 65 patients. Diagnostic material was obtained in 53 patients. Non-diagnostic material was obtained in 12 patients. Five out of the 12 patients with non-diagnostic material had repeat biopsies with diagnostic material obtained in 2 of these. No major complications occurred in any patient. Conclusion: CT-guided bone biopsy using a hand held commercial drill has a technically high success rate with minimal complications.

  2. SHIELDING AND DETECTOR RESPONSE CALCULATIONS PERTAINING TO CATEGORY 1 QUANTITIES OF PLUTONIUM AND HAND-HELD PLASTIC SCINTILLATORS

    Energy Technology Data Exchange (ETDEWEB)

    Couture, A.

    2013-06-07

    Nuclear facilities sometimes use hand-held plastic scintillator detectors to detect attempts to divert special nuclear material in situations where portal monitors are impractical. MCNP calculations have been performed to determine the neutron and gamma radiation field arising from a Category I quantity of weapons-grade plutonium in various shielding configurations. The shields considered were composed of combinations of lead and high-density polyethylene such that the mass of the plutonium plus shield was 22.7 kilograms. Monte-Carlo techniques were also used to determine the detector response to each of the shielding configurations. The detector response calculations were verified using field measurements of high-, medium-, and low- energy gamma-ray sources as well as a Cf-252 neutron source.

  3. HAND-HELD GAMMA-RAY SPECTROMETER BASED ON HIGH-EFFICIENCY FRISCH-RING CdZnTe DETECTORS.

    Energy Technology Data Exchange (ETDEWEB)

    CUI,Y.

    2007-05-01

    Frisch-ring CdZnTe detectors have demonstrated good energy resolution, el% FWHM at 662 keV, and good efficiency for detecting gamma rays. This technique facilitates the application of CdZnTe materials for high efficiency gamma-ray detection. A hand-held gamma-ray spectrometer based on Frisch-ring detectors is being designed at Brookhaven National Laboratory. It employs an 8x8 CdZnTe detector array to achieve a high volume of 19.2 cm3, so that detection efficiency is significantly improved. By using the front-end ASICs developed at BNL, this spectrometer has a small profile and high energy resolution. The spectrometer includes signal processing circuit, digitization and storage circuit, high-voltage module, and USB interface. In this paper, we introduce the details of the system structure and report our test results with it.

  4. Hand-held multi-DOF robotic forceps for neurosurgery designed for dexterous manipulation in deep and narrow space.

    Science.gov (United States)

    Okubo, Takuro; Harada, Kanako; Fujii, Masahiro; Tanaka, Shinichi; Ishimaru, Tetsuya; Iwanaka, Tadashi; Nakatomi, Hirohumi; Sora, Sigeo; Morita, Akio; Sugita, Naohiko; Mitsuishi, Mamoru

    2014-01-01

    Neurosurgical procedures require precise and dexterous manipulation of a surgical suture in narrow and deep spaces in the brain. This is necessary for surgical tasks such as the anastomosis of microscopic blood vessels and dura mater suturing. A hand-held multi-degree of freedom (DOF) robotic forceps was developed to aid the performance of such difficult tasks. The diameter of the developed robotic forceps is 3.5 mm, and its tip has three DOFs, namely, bending, rotation, and grip. Experimental results showed that the robotic forceps had an average needle insertion force of 1.7 N. Therefore, an increase in the needle insertion force is necessary for practical application of the developed device.

  5. US-ROK Action Sheet 34: Safeguards Application of a Hand-held Mechanically Cooled Germanium Spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Dreyer, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Burks, M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Ham, Y. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kwak, S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-10-20

    This report summarizes results of Action Sheet 34 - for the cooperative efforts on the field testing and evaluation of a high-resolution, hand-held, gamma-ray spectrometer, known as SPG (Spectroscopic Planar Germanium), for safeguards application such as short notice inspections, UF6 analysis, enrichment determination, and other potential applications. The Spectroscopic Planar Germanium (SPG) has been demonstrated IAEA Physical Inventory Verification (PIV) in South Korea. This field test was a success and the feedback provided by KINAC, IAEA, and national laboratory staff was used to direct efforts to improve the instrument this year. Key points in this report include measurement results from PIV, analysis of spectra with commercially available Ortec U235 and PC-FRAM, and completion of tripod and tungsten collimator and integration of user feedback.

  6. Real-time hand-held ultrasound medical-imaging device based on a new digital quadrature demodulation processor.

    Science.gov (United States)

    Levesque, Philippe; Sawan, Mohamad

    2009-08-01

    A fully hardware-based real-time digital wideband quadrature demodulation processor based on the Hilbert transform is proposed to process ultrasound radio frequency signals. The presented architecture combines 2 finite impulse response (FIR) filters to process in-phase and quadrature signals and includes a piecewise linear approximation architecture that performs the required square root operations. The proposed implementation enables flexibility to support different transducers with its ability to load on-the-fly different FIR filter coefficient sets. The complexity and accuracy of the demodulator processor are analyzed with simulated RF data; a normalized residual sum-of-squares cost function is used for comparison with the Matlab Hilbert function. Three implementations are integrated into a hand-held ultrasound system for experimental accuracy and performance evaluation. Real-time images were acquired from a reference phantom, demonstrating the feasibility of using the presented architecture to perform real-time digital quadrature demodulation of ultrasonic signal echoes. Experimental results show that the implementation, using only 2942 slices and 3 dedicated digital multipliers of a low-cost and low-power field-programmable gate array (FPGA) is accurate relative to a comparable software- based system; axial and lateral resolution of 1 mm and 2 mm, respectively, were obtained with a 12-mm piezoelectric transducer without postprocessing. Because the processing and sampling rates are the same, high-frequency ultrasound signals can be processed as well. For a 15-frame-per-second display, the hand-held ultrasonic imaging-processing core (FPGA, memory) requires only 45 mW (dynamic) when using a 5-MHz single-element piezoelectric transducer.

  7. Hand-held portable desorption atmospheric pressure chemical ionization ion source for in situ analysis of nitroaromatic explosives.

    Science.gov (United States)

    Jjunju, Fred P M; Maher, Simon; Li, Anyin; Syed, Sarfaraz U; Smith, Barry; Heeren, Ron M A; Taylor, Stephen; Cooks, R Graham

    2015-10-06

    A novel, lightweight (0.6 kg), solvent- and gas-cylinder-free, hand-held ion source based on desorption atmospheric pressure chemical ionization has been developed and deployed for the analysis of nitroaromatic explosives on surfaces in open air, offering portability for in-field analysis. A small, inexpensive, rechargeable lithium polymer battery was used to power the custom-designed circuitry within the device, which generates up to ±5 kV dc voltage to ignite a corona discharge plasma in air for up to 12 h of continuous operation, and allowing positive- and negative-ion mass spectrometry. The generated plasma is pneumatically transported to the surface to be interrogated by ambient air at a rate of 1-3.5 L/min, compressed using a small on-board diaphragm pump. The plasma source allows liquid or solid samples to be examined almost instantaneously without any sample preparation in the open environment. The advantages of low carrier gas and low power consumption (<6 W), as well as zero solvent usage, have aided in developing the field-ready, hand-held device for trigger-based, "near-real-time" sampling/ionization. Individual nitroaromatic explosives (such as 2,4,6-trinitrotoluene) can be easily detected in amounts as low as 5.8 pg with a linear dynamic range of at least 10 (10-100 pg), a relative standard deviation of ca. 7%, and an R(2) value of 0.9986. Direct detection of several nitroaromatic compounds in a complex mixture without prior sample preparation is demonstrated, and their identities are confirmed by tandem mass spectrometry fragmentation patterns.

  8. Assessment of Lower Limb Muscle Strength and Power Using Hand-Held and Fixed Dynamometry: A Reliability and Validity Study.

    Science.gov (United States)

    Mentiplay, Benjamin F; Perraton, Luke G; Bower, Kelly J; Adair, Brooke; Pua, Yong-Hao; Williams, Gavin P; McGaw, Rebekah; Clark, Ross A

    2015-01-01

    Hand-held dynamometry (HHD) has never previously been used to examine isometric muscle power. Rate of force development (RFD) is often used for muscle power assessment, however no consensus currently exists on the most appropriate method of calculation. The aim of this study was to examine the reliability of different algorithms for RFD calculation and to examine the intra-rater, inter-rater, and inter-device reliability of HHD as well as the concurrent validity of HHD for the assessment of isometric lower limb muscle strength and power. 30 healthy young adults (age: 23±5 yrs, male: 15) were assessed on two sessions. Isometric muscle strength and power were measured using peak force and RFD respectively using two HHDs (Lafayette Model-01165 and Hoggan microFET2) and a criterion-reference KinCom dynamometer. Statistical analysis of reliability and validity comprised intraclass correlation coefficients (ICC), Pearson correlations, concordance correlations, standard error of measurement, and minimal detectable change. Comparison of RFD methods revealed that a peak 200 ms moving window algorithm provided optimal reliability results. Intra-rater, inter-rater, and inter-device reliability analysis of peak force and RFD revealed mostly good to excellent reliability (coefficients ≥ 0.70) for all muscle groups. Concurrent validity analysis showed moderate to excellent relationships between HHD and fixed dynamometry for the hip and knee (ICCs ≥ 0.70) for both peak force and RFD, with mostly poor to good results shown for the ankle muscles (ICCs = 0.31-0.79). Hand-held dynamometry has good to excellent reliability and validity for most measures of isometric lower limb strength and power in a healthy population, particularly for proximal muscle groups. To aid implementation we have created freely available software to extract these variables from data stored on the Lafayette device. Future research should examine the reliability and validity of these variables in clinical

  9. Assessment of Lower Limb Muscle Strength and Power Using Hand-Held and Fixed Dynamometry: A Reliability and Validity Study.

    Directory of Open Access Journals (Sweden)

    Benjamin F Mentiplay

    Full Text Available Hand-held dynamometry (HHD has never previously been used to examine isometric muscle power. Rate of force development (RFD is often used for muscle power assessment, however no consensus currently exists on the most appropriate method of calculation. The aim of this study was to examine the reliability of different algorithms for RFD calculation and to examine the intra-rater, inter-rater, and inter-device reliability of HHD as well as the concurrent validity of HHD for the assessment of isometric lower limb muscle strength and power.30 healthy young adults (age: 23±5 yrs, male: 15 were assessed on two sessions. Isometric muscle strength and power were measured using peak force and RFD respectively using two HHDs (Lafayette Model-01165 and Hoggan microFET2 and a criterion-reference KinCom dynamometer. Statistical analysis of reliability and validity comprised intraclass correlation coefficients (ICC, Pearson correlations, concordance correlations, standard error of measurement, and minimal detectable change.Comparison of RFD methods revealed that a peak 200 ms moving window algorithm provided optimal reliability results. Intra-rater, inter-rater, and inter-device reliability analysis of peak force and RFD revealed mostly good to excellent reliability (coefficients ≥ 0.70 for all muscle groups. Concurrent validity analysis showed moderate to excellent relationships between HHD and fixed dynamometry for the hip and knee (ICCs ≥ 0.70 for both peak force and RFD, with mostly poor to good results shown for the ankle muscles (ICCs = 0.31-0.79.Hand-held dynamometry has good to excellent reliability and validity for most measures of isometric lower limb strength and power in a healthy population, particularly for proximal muscle groups. To aid implementation we have created freely available software to extract these variables from data stored on the Lafayette device. Future research should examine the reliability and validity of these variables in

  10. Cellphone-Based Hand-Held Microplate Reader for Point-of-Care Testing of Enzyme-Linked Immunosorbent Assays.

    Science.gov (United States)

    Berg, Brandon; Cortazar, Bingen; Tseng, Derek; Ozkan, Haydar; Feng, Steve; Wei, Qingshan; Chan, Raymond Yan-Lok; Burbano, Jordi; Farooqui, Qamar; Lewinski, Michael; Di Carlo, Dino; Garner, Omai B; Ozcan, Aydogan

    2015-08-25

    Standard microplate based enzyme-linked immunosorbent assays (ELISA) are widely utilized for various nanomedicine, molecular sensing, and disease screening applications, and this multiwell plate batched analysis dramatically reduces diagnosis costs per patient compared to nonbatched or nonstandard tests. However, their use in resource-limited and field-settings is inhibited by the necessity for relatively large and expensive readout instruments. To mitigate this problem, we created a hand-held and cost-effective cellphone-based colorimetric microplate reader, which uses a 3D-printed opto-mechanical attachment to hold and illuminate a 96-well plate using a light-emitting-diode (LED) array. This LED light is transmitted through each well, and is then collected via 96 individual optical fibers. Captured images of this fiber-bundle are transmitted to our servers through a custom-designed app for processing using a machine learning algorithm, yielding diagnostic results, which are delivered to the user within ∼1 min per 96-well plate, and are visualized using the same app. We successfully tested this mobile platform in a clinical microbiology laboratory using FDA-approved mumps IgG, measles IgG, and herpes simplex virus IgG (HSV-1 and HSV-2) ELISA tests using a total of 567 and 571 patient samples for training and blind testing, respectively, and achieved an accuracy of 99.6%, 98.6%, 99.4%, and 99.4% for mumps, measles, HSV-1, and HSV-2 tests, respectively. This cost-effective and hand-held platform could assist health-care professionals to perform high-throughput disease screening or tracking of vaccination campaigns at the point-of-care, even in resource-poor and field-settings. Also, its intrinsic wireless connectivity can serve epidemiological studies, generating spatiotemporal maps of disease prevalence and immunity.

  11. Validation of a new hand-held electronic data capture method for continuous monitoring of subjective appetite sensations

    Directory of Open Access Journals (Sweden)

    King Neil

    2011-06-01

    Full Text Available Abstract Background When large scale trials are investigating the effects of interventions on appetite, it is paramount to efficiently monitor large amounts of human data. The original hand-held Electronic Appetite Ratings System (EARS was designed to facilitate the administering and data management of visual analogue scales (VAS of subjective appetite sensations. The purpose of this study was to validate a novel hand-held method (EARS II (HP® iPAQ against the standard Pen and Paper (P&P method and the previously validated EARS. Methods Twelve participants (5 male, 7 female, aged 18-40 were involved in a fully repeated measures design. Participants were randomly assigned in a crossover design, to either high fat (>48% fat or low fat (ad libitum lunch was provided immediately before completing a final set of appetite sensations. Results Repeated measures ANOVAs were conducted for ratings of hunger, fullness and desire to eat. There were no significant differences between P&P compared with either EARS or EARS II (p > 0.05. Correlation coefficients between P&P and EARS II, controlling for age and gender, were performed on Area Under the Curve ratings. R2 for Hunger (0.89, Fullness (0.96 and Desire to Eat (0.95 were statistically significant (p Conclusions EARS II was sensitive to the impact of a meal and recovery of appetite during the postprandial period and is therefore an effective device for monitoring appetite sensations. This study provides evidence and support for further validation of the novel EARS II method for monitoring appetite sensations during large scale studies. The added versatility means that future uses of the system provides the potential to monitor a range of other behavioural and physiological measures often important in clinical and free living trials. This study was registered as a clinical trial by Current Controlled Trials (Registration Number - ISRCTN47291569.

  12. Gun Safety

    Science.gov (United States)

    Many U.S. households have guns, but they can cause harm if not handled properly. Here are some things you can do to keep yourself and ... safe: Teach children that they shouldn't touch guns and that if they see a gun, to ...

  13. Hip- and knee-strength assessments using a hand-held dynamometer with external belt-fixation are inter-tester reliable

    DEFF Research Database (Denmark)

    Thorborg, Kristian; Bandholm, Thomas; Hölmich, Per

    2013-01-01

    PURPOSE: In football, ice-hockey, and track and field, injuries have been predicted, and hip- and knee-strength deficits quantified using hand-held dynamometry (HHD). However, systematic bias exists when testers of different sex and strength perform the measurements. Belt-fixation of the dynamome......PURPOSE: In football, ice-hockey, and track and field, injuries have been predicted, and hip- and knee-strength deficits quantified using hand-held dynamometry (HHD). However, systematic bias exists when testers of different sex and strength perform the measurements. Belt...

  14. Hand-held dynamometry in patients with haematological malignancies: Measurement error in the clinical assessment of knee extension strength

    Directory of Open Access Journals (Sweden)

    Uebelhart Daniel

    2009-03-01

    Full Text Available Abstract Background Hand-held dynamometry is a portable and inexpensive method to quantify muscle strength. To determine if muscle strength has changed, an examiner must know what part of the difference between a patient's pre-treatment and post-treatment measurements is attributable to real change, and what part is due to measurement error. This study aimed to determine the relative and absolute reliability of intra and inter-observer strength measurements with a hand-held dynamometer (HHD. Methods Two observers performed maximum voluntary peak torque measurements (MVPT for isometric knee extension in 24 patients with haematological malignancies. For each patient, the measurements were carried out on the same day. The main outcome measures were the intraclass correlation coefficient (ICC ± 95%CI, the standard error of measurement (SEM, the smallest detectable difference (SDD, the relative values as % of the grand mean of the SEM and SDD, and the limits of agreement for the intra- and inter-observer '3 repetition average' and the 'highest value of 3 MVPT' knee extension strength measures. Results The intra-observer ICCs were 0.94 for the average of 3 MVPT (95%CI: 0.86–0.97 and 0.86 for the highest value of 3 MVPT (95%CI: 0.71–0.94. The ICCs for the inter-observer measurements were 0.89 for the average of 3 MVPT (95%CI: 0.75–0.95 and 0.77 for the highest value of 3 MVPT (95%CI: 0.54–0.90. The SEMs for the intra-observer measurements were 6.22 Nm (3.98% of the grand mean (GM and 9.83 Nm (5.88% of GM. For the inter-observer measurements, the SEMs were 9.65 Nm (6.65% of GM and 11.41 Nm (6.73% of GM. The SDDs for the generated parameters varied from 17.23 Nm (11.04% of GM to 27.26 Nm (17.09% of GM for intra-observer measurements, and 26.76 Nm (16.77% of GM to 31.62 Nm (18.66% of GM for inter-observer measurements, with similar results for the limits of agreement. Conclusion The results indicate that there is acceptable relative reliability

  15. Hand-Held Keyboard

    Science.gov (United States)

    1994-01-01

    The Data Egg, a prototype chord key-based data entry device, can be used autonomously or as an auxiliary keyboard with a personal computer. Data is entered by pressing combinations of seven buttons positioned where the fingers naturally fall when clasping the device. An experienced user can enter text at 30 to 35 words per minute. No transcription is required. The input is downloaded into a computer and printed. The Data Egg can be used by an astronaut in space, a journalist, a bedridden person, etc. It was developed by a Jet Propulsion Laboratory engineer. Product is not currently manufactured.

  16. Comparison of a digital and an optical analogue hand-held refractometer for the measurement of canine urine specific gravity.

    Science.gov (United States)

    Paris, J K; Bennett, A D; Dodkin, S J; Gunn-Moore, D A

    2012-05-05

    Urine specific gravity (USG) is used clinically as a measure of urine concentration, and is routinely assessed by refractometry. A comparison between optical analogue and digital refractometers for evaluation of canine urine has not been reported. The aim of this study was to compare a digital and an optical analogue hand-held refractometer for the measurement of canine USG, and to assess correlation with urine osmolality. Prospective study. Free-catch urine samples were collected from 285 hospitalised adult dogs, and paired USG readings were obtained with a digital and an optical analogue refractometer. In 50 dogs, urine osmolality was also measured using a freezing point depression osmometer. There was a small but statistically significant difference between the two refractometers (P<0.001), with the optical analogue refractometer reading higher than the digital refractometer (mean difference 0.0006, sd 0.0012). Paired refractometer measurements varied by <0.002 in 91.5 per cent of cases. The optical analogue and digital refractometer readings showed excellent correlation with osmolality (r=0.980 and r=0.977, respectively, P<0.001 in both cases). Despite statistical significance, the difference between the two refractometers is unlikely to be clinically significant. Both instruments provide an accurate assessment of USG in dogs.

  17. Four dimensional hybrid ultrasound and optoacoustic imaging via passive element optical excitation in a hand-held probe

    Energy Technology Data Exchange (ETDEWEB)

    Fehm, Thomas Felix; Razansky, Daniel, E-mail: dr@tum.de [Institute for Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, Neuherberg (Germany); Faculty of Medicine, Technische Universität München, Munich (Germany); Deán-Ben, Xosé Luís [Institute for Biological and Medical Imaging (IBMI), Helmholtz Zentrum München, Neuherberg (Germany)

    2014-10-27

    Ultrasonography and optoacoustic imaging share powerful advantages related to the natural aptitude for real-time image rendering with high resolution, the hand-held operation, and lack of ionizing radiation. The two methods also possess very different yet highly complementary advantages of the mechanical and optical contrast in living tissues. Nonetheless, efficient integration of these modalities remains challenging owing to the fundamental differences in the underlying physical contrast, optimal signal acquisition, and image reconstruction approaches. We report on a method for hybrid acquisition and reconstruction of three-dimensional pulse-echo ultrasound and optoacoustic images in real time based on passive ultrasound generation with an optical absorber, thus avoiding the hardware complexity of active ultrasound generation. In this way, complete hybrid datasets are generated with a single laser interrogation pulse, resulting in simultaneous rendering of ultrasound and optoacoustic images at an unprecedented rate of 10 volumetric frames per second. Performance is subsequently showcased in phantom experiments and in-vivo measurements from a healthy human volunteer, confirming general clinical applicability of the method.

  18. The usefulness and limitations of hand-held refractometers in veterinary laboratory medicine: an historical and technical review.

    Science.gov (United States)

    George, Jeanne W.

    2001-01-01

    Medical hand-held refractometers have been used in veterinary practice since their development in the 1960s. They have become ubiquitous for the measurement of protein and urine solute concentrations because of their rapidity of analysis, ease of use, and relatively low cost. Refraction of light offers advantages for the determination of solute concentrations because the measurement requires no chemical alteration of the specimen. Numerous authors have reported that the results of protein estimation by refractometry for domestic mammals correlate well with those obtained by the biuret method, although others have reported both higher and lower refractometric results compared with biuret results. Major discrepancies between biuret and refractometric results have been reported for avian samples. Some of the variation in reported results may be due to differences in design by refractometer manufacturers. Another possible source may be variation in the biuret reagent mixture and assay conditions. Refractometers also can be used to calculate serum water concentration. A table that converts index of refraction to serum water concentration can be used to convert electrolyte concentration from mmol/L of serum to mmol/L of serum water, a more accurate indicator of effective electrolyte concentration. Refractometers are especially useful for determining urine specific gravity on veterinary samples because they require relatively small sample volumes. Specific gravity continues to be the most common unit for reporting total solids concentration. Some solutes, such as acetone, may cause false increases in specific gravity by refractometry, as they increase refraction but are less dense than water.

  19. Task difficulty and inertial properties of hand-held tools: An assessment of their concurrent effects on precision aiming.

    Science.gov (United States)

    Silva, Paula L; Bootsma, Reinoud J; Figueiredo, Priscilla Rezende Pereira; Avelar, Bruna Silva; de Andrade, André Gustavo Pereira; Fonseca, Sérgio T; Mancini, Marisa Cotta

    2016-08-01

    Aiming hand-held tools at targets in space entails adjustments in the dynamical organization of aiming patterns according to the required precision. We asked whether and how these adjustments are modified by the tool's mass distribution. Twelve participants performed reciprocal aiming movements with a 50-cm long wooden probe. Kinematic patterns of probe movements were used as a window into the behavioral dynamic underlying performance of a reciprocal aiming task. We crossed three levels of task difficulty (IDs 2.8, 4.5 and 6.1) with two types of probe varying in their mass distribution (proximal vs distal loading). Movement duration was affected by task difficulty and probe loading (shorter for larger targets and proximal probe loading). Progressive deviations from a sinusoidal movement pattern were observed as task difficulty increased. Such deviations were more pronounced with proximal probe loading. Results point to a higher degree of non-linearity in aiming dynamics when the probe was loaded proximally, which might reflect employment of additional perceptual-motor processes to control the position of its less stable tip at the vicinity of the targets. More generally, the effects of probe loading on aiming pattern and dynamics suggest that perceptual-motor processes responding to task level constraints are sensitive to, and not independent from, biomechanical, end-effector constraints.

  20. Effects of a new mild shampoo for preventing hair loss in Asian by a simple hand-held phototrichogram technique.

    Science.gov (United States)

    Baek, J H; Lee, S Y; Yoo, M; Park, W-S; Lee, S J; Boo, Y C; Koh, J-S

    2011-12-01

    This study was conducted to evaluate the effects of a commercially available shampoo in Korean subjects with alopecia using a simple hand-held phototrichogram technique. Forty-four subjects with alopecia were enrolled and forty subjects continued for 16 weeks. In the test group, total hair counts increased significantly at weeks 8 and 16, and the number of shedding hair significantly decreased at week 16. Terminal hair counts significantly increased at week 8. In the control group, hair thickness and the number of vellus hairs significantly decreased at week 16. The number of total hairs significantly increased in the test group than in the control group at weeks 8 and 16. The number of shedding hairs significantly decreased in the test group than in the control group at week 16. Visual assessment using clinical digital images showed that the number of total hairs appeared to increase although there was no statistical significance. In this study, it was found that the test shampoo could prevent hair loss.

  1. Test-retest reliabilities of hand-held dynamometer for lower-limb muscle strength in intellectual disabilities.

    Science.gov (United States)

    Wuang, Yee-Pay; Chang, Jyh-Jong; Wang, Min-Hung; Lin, Hsiu-Ching

    2013-08-01

    The primary purpose of this study was to investigate the test-retest reliabilities of hand-held dynamometer (HDD) for measuring lower-limb muscle strength in intellectual disabilities (ID). The other purposes were to: (1) compare the lower-limb muscle strength between children with and without ID; (2) probe the relationship between the muscle forces and agility performance in ID; and (3) explore the factors associated with muscle strength in ID. Sixty-one participants (30 boys and 31 girls; mean age=14.1 ± 3.3 year) were assessed by the HDD using a "make" test. The comparative group consisted of 63 typically developing children (33 boys and 30 girls; mean age=14.9 ± 2.1 year). The ID group demonstrated lower muscle groups than in typically developing group. Except for the ankle plantarflexors (ICC=0.69, SEM=0.72), test-retest analysis showed good intrarater reliability with ICC ranging from 0.81 to 0.96, and intrarater SEM values ranged from 0.40 to 0.57. The HDD has the potential to be a reliable tool for strength measurement in ID. Muscle strength was positively related to agility performance. Regression analysis indicated that height, weight, BMI, and activity level were significant predictors of muscle strength in ID.

  2. Forest Inventory with Terrestrial LiDAR: A Comparison of Static and Hand-Held Mobile Laser Scanning

    Directory of Open Access Journals (Sweden)

    Sébastien Bauwens

    2016-06-01

    Full Text Available The application of static terrestrial laser scanning (TLS in forest inventories is becoming more effective. Nevertheless, the occlusion effect is still limiting the processing efficiency to extract forest attributes. The use of a mobile laser scanner (MLS would reduce this occlusion. In this study, we assessed and compared a hand-held mobile laser scanner (HMLS with two TLS approaches (single scan: SS, and multi scan: MS for the estimation of several forest parameters in a wide range of forest types and structures. We found that SS is competitive to extract the ground surface of forest plots, while MS gives the best result to describe the upper part of the canopy. The whole cross-section at 1.3 m height is scanned for 91% of the trees (DBH > 10 cm with the HMLS leading to the best results for DBH estimates (bias of −0.08 cm and RMSE of 1.11 cm, compared to no fully-scanned trees for SS and 42% fully-scanned trees for MS. Irregularities, such as bark roughness and non-circular cross-section may explain the negative bias encountered for all of the scanning approaches. The success of using MLS in forests will allow for 3D structure acquisition on a larger scale and in a time-efficient manner.

  3. Inter-Tester Reliability and Precision of Manual Muscle Testing and Hand-Held Dynamometry in Lower Limb Muscles of Children with Spina Bifida

    Science.gov (United States)

    Mahony, Kate; Hunt, Adrienne; Daley, Deborah; Sims, Susan; Adams, Roger

    2009-01-01

    Reliability and measurement precision of manual muscle testing (MMT) and hand-held dynamometry (HHD) were compared for children with spina bifida. Strength measures were obtained of the hip flexors, hip abductors, and knee extensors of 20 children (10 males, 10 females; mean age 9 years 10 months; range: 5 to 15 years) by two experienced physical…

  4. Inter-Tester Reliability and Precision of Manual Muscle Testing and Hand-Held Dynamometry in Lower Limb Muscles of Children with Spina Bifida

    Science.gov (United States)

    Mahony, Kate; Hunt, Adrienne; Daley, Deborah; Sims, Susan; Adams, Roger

    2009-01-01

    Reliability and measurement precision of manual muscle testing (MMT) and hand-held dynamometry (HHD) were compared for children with spina bifida. Strength measures were obtained of the hip flexors, hip abductors, and knee extensors of 20 children (10 males, 10 females; mean age 9 years 10 months; range: 5 to 15 years) by two experienced physical…

  5. Beyond Textbook Illustrations: Hand-Held Models of Ordered DNA and Protein Structures as 3D Supplements to Enhance Student Learning of Helical Biopolymers

    Science.gov (United States)

    Jittivadhna, Karnyupha; Ruenwongsa, Pintip; Panijpan, Bhinyo

    2010-01-01

    Textbook illustrations of 3D biopolymers on printed paper, regardless of how detailed and colorful, suffer from its two-dimensionality. For beginners, computer screen display of skeletal models of biopolymers and their animation usually does not provide the at-a-glance 3D perception and details, which can be done by good hand-held models. Here, we…

  6. Yield of screening for atrial fibrillation in primary care with a hand-held, single-lead electrocardiogram device during influenza vaccination

    NARCIS (Netherlands)

    Kaasenbrood, Femke; Hollander, Monika; Rutten, Frans H.; Gerhards, Leo J.; Hoes, Arno W.; Tieleman, Robert G.

    2016-01-01

    Aims To assess the yield of screening for atrial fibrillation (AF) with a hand-held single-lead electrocardiogram (ECG) device during influenza vaccination in primary care in the Netherlands. Methods and results We used the MyDiagnostick to screen for AF in persons who participated in influenza vacc

  7. Maintaining radiation exposures as low as reasonably achievable (ALARA) for dental personnel operating portable hand-held x-ray equipment.

    Science.gov (United States)

    McGiff, Thomas J; Danforth, Robert A; Herschaft, Edward E

    2012-08-01

    Clinical experience indicates that newly available portable hand-held x-ray units provide advantages compared to traditional fixed properly installed and operated x-ray units in dental radiography. However, concern that hand-held x-ray units produce higher operator doses than fixed x-ray units has caused regulatory agencies to mandate requirements for use of hand-held units that go beyond those recommended by the manufacturer and can discourage the use of this technology. To assess the need for additional requirements, a hand-held x-ray unit and a pair of manikins were used to measure the dose to a simulated operator under two conditions: exposures made according to the manufacturer's recommendations and exposures made according to manufacturer's recommendation except for the removal of the x-ray unit's protective backscatter shield. Dose to the simulated operator was determined using an array of personal dosimeters and a pair of pressurized ion chambers. The results indicate that the dose to an operator of this equipment will be less than 0.6 mSv y⁻¹ if the device is used according to the manufacturer's recommendations. This suggests that doses to properly trained operators of well-designed, hand-held dental x-ray units will be below 1.0 mSv y⁻¹ (2% of the annual occupational dose limit) even if additional no additional operational requirements are established by regulatory agencies. This level of annual dose is similar to those reported as typical dental personnel using fixed x-ray units and appears to satisfy the ALARA principal for this class of occupational exposures.

  8. The Fluostick, a real hand-held system for near-infrared fluorescence image-guided surgery

    Science.gov (United States)

    Dorval, Paul; Mangeret, Norman; Guillermet, Stephanie; Righini, Christian Adrien; Barabino, Gabriele; Rizo, Philippe; Poulet, Patrick

    2014-02-01

    Near-infrared fluorescence image-guided surgery, FIGS, has lately shown a huge potential in oncologic and lymphatic related surgeries. In some indications such as liver or heart surgery, fluorescence-reachable anatomic structures are limited by the access to the surgical field. Nevertheless, most of the systems available on the market are too large to image the sides of cavities. Small devices are clearly required to improve workability of fluorescence imaging systems. The current work describes the development of an instrument and the results of its evaluation. In order to image narrow area, we developed a small size device consisting of an optical head connected to a control box. The whole system, optical head, control box and software, receives a CE mark for clinical procedures. Building on existing technologies, we simplified the fluorescence imaging system. It consists of a custom charged-coupled device camera, a high color rendering index visible LED illumination and a Class1 Laser fluorophore excitation. With a curved shape of 25x35x150mm, the optical head was designed as a true hand-held probe. The field of view varies from 5x3.75cm to 2x1.5cm. The device is able to collect and display the signal of 5pmol of IndoCyanine Green (ICG) with a spatial resolution down to 70μm at 25 frames per second. The system has been evaluated in pre-clinical and clinical procedures. The preclinical studies confirmed the ability of the system to visualize tumors in mice models. Clinical evaluations includes lymphedema investigations and surgical resections of tumors in colorectal cancer.

  9. Limitations of Condensed Teaching Strategies to Develop Hand-Held Cardiac Ultrasonography Skills in Internal Medicine Residents.

    Science.gov (United States)

    Wilkinson, Jeffrey S; Barake, Walid; Smith, Chris; Thakrar, Amar; Johri, Amer M

    2016-08-01

    Advances in ultrasonographic technology have allowed for hand-held cardiac ultrasonography (HHCU) units that fit into a physician's laboratory coat. Recently, studies to educate internal medicine residents have shown promise. The optimal duration and methodology for teaching HHCU skills has not been established. Over a 1-year period, internal medicine residents were recruited during their cardiology ward rotation into a single-centre nonblinded randomized trial. The 2 condensed teaching strategies were (1) a conventional ward-based program and (2) a technology-driven simulation-based strategy. Outcomes were evaluated by (1) an objective structured clinical examination (OSCE) to evaluate interpretation ability (assessing both type I and type II error rates) and (2) demonstration of HHCU skills graded by 2 level III echocardiographers. Twenty-four internal medicine residents were randomized. After teaching, the conventional teaching group had a significant absolute increase in the ability to make a singular correct diagnosis (20%; P < 0.001). In the technology arm, making a singular correct diagnosis increased 24% from baseline (P = 0.001). Interpretation skill was not significantly different between groups. The false-positive rate increased by an absolute 14% and 17% in the conventional and technology groups, respectively (P = 0.079 and P = 0.008). Our findings suggest that HHCU interpretation skills improve after either a conventional ward-based or a technology-driven approach. However, our study emphasizes the important limitations of both teaching programs, because we detected a trend toward an increase in the false-positive rate after both approaches. This suggests that a short duration of training may not be sufficient for HHCU to be performed in a safe manner.

  10. Segmentation of Environmental Time Lapse Image Sequences for the Determination of Shore Lines Captured by Hand-Held Smartphone Cameras

    Science.gov (United States)

    Kröhnert, M.; Meichsner, R.

    2017-09-01

    The relevance of globally environmental issues gains importance since the last years with still rising trends. Especially disastrous floods may cause in serious damage within very short times. Although conventional gauging stations provide reliable information about prevailing water levels, they are highly cost-intensive and thus just sparsely installed. Smartphones with inbuilt cameras, powerful processing units and low-cost positioning systems seem to be very suitable wide-spread measurement devices that could be used for geo-crowdsourcing purposes. Thus, we aim for the development of a versatile mobile water level measurement system to establish a densified hydrological network of water levels with high spatial and temporal resolution. This paper addresses a key issue of the entire system: the detection of running water shore lines in smartphone images. Flowing water never appears equally in close-range images even if the extrinsics remain unchanged. Its non-rigid behavior impedes the use of good practices for image segmentation as a prerequisite for water line detection. Consequently, we use a hand-held time lapse image sequence instead of a single image that provides the time component to determine a spatio-temporal texture image. Using a region growing concept, the texture is analyzed for immutable shore and dynamic water areas. Finally, the prevalent shore line is examined by the resultant shapes. For method validation, various study areas are observed from several distances covering urban and rural flowing waters with different characteristics. Future work provides a transformation of the water line into object space by image-to-geometry intersection.

  11. Is Hand-Held Optical Coherence Tomography Reliable in Infants and Young Children with and without Nystagmus?

    Science.gov (United States)

    Lee, Helena; Proudlock, Frank; Gottlob, Irene

    2014-01-01

    Purpose To evaluate the reliability of the spectral domain hand-held OCT (HH-OCT) in assessing foveal morphology in children with and without nystagmus. Methods Forty-nine subjects with nystagmus (mean age 43.83 months; range 1-82 months) and 48 controls (mean age 43.02 months; range 0 to 83 months were recruited and scanned using HH-OCT (Bioptigen). A minimum of 2 separate volumetric scans on the same examination day of the fovea were obtained. The images were imported into ImageJ software where manual retinal layer segmentation of the central foveal B-scan was performed. Agreement between scans was assessed by determining the intraclass correlation coefficients (ICC) and Bland–Altman plots. Results Both the nystagmus and controls groups showed an excellent degree of reproducibility between two examinations with ICCs greater than 0.96 for central macular thickness (CMT) and greater than 0.8 for the outer nuclear layer and outer segment of the photoreceptors. The nerve fiber layer, ganglion cell layer, outer plexiform layer, inner segment of the photoreceptors and retinal pigment epithelium were less reliable with ICCs of less than 0.7. There was no difference in the reliability of scans obtained in children with nystagmus as compared to controls and both groups had good inter-eye agreement with ICCs greater than 0.94 for CMT. Conclusion We have shown for the first time that the HH-OCT provides reliable measurements in children with and without nystagmus. This is important as the HH-OCT will have a greater diagnostic and prognostic role in young children with nystagmus and other eye diseases in the future. PMID:24222299

  12. Electromagnetic Gun

    Institute of Scientific and Technical Information of China (English)

    1995-01-01

    In the early 14th century,Europeons used guns in battle for the first time. The secret was gunpowder,a volatile mixture of chemicals that exploded when lit. Since then,all guns have relied on gunpowder or other chemical propellants.

  13. Systemic Administration of CpG Oligodeoxynucleotide and Levamisole as Adjuvants for Gene-Gun-Delivered Antitumor DNA Vaccines

    Science.gov (United States)

    Šmahel, Michal; Poláková, Ingrid; Sobotková, Eva; Vajdová, Eva

    2011-01-01

    DNA vaccines showed great promise in preclinical models of infectious and malignant diseases, but their potency was insufficient in clinical trials and is needed to be improved. In this study, we tested systemic administration of two conventional adjuvants, synthetic oligodeoxynucleotide carrying immunostimulatory CpG motifs (CpG-ODN) and levamisole (LMS), and evaluated their effect on immune reactions induced by DNA vaccines delivered by a gene gun. DNA vaccination was directed either against the E7 oncoprotein of human papillomavirus type 16 or against the BCR-ABL1 oncoprotein characteristic for chronic myeloid leukemia. High doses of both adjuvants reduced activation of mouse splenic CD8+ T lymphocytes, but the overall antitumor effect was enhanced in both tumor models. High-dose CpG-ODN exhibited a superior adjuvant effect in comparison with any combination of CpG-ODN with LMS. In summary, our results demonstrate the benefit of combined therapy with gene-gun-delivered antitumor DNA vaccines and systemic administration of CpG-ODN or LMS. PMID:22028727

  14. Systemic Administration of CpG Oligodeoxynucleotide and Levamisole as Adjuvants for Gene-Gun-Delivered Antitumor DNA Vaccines

    Directory of Open Access Journals (Sweden)

    Michal Šmahel

    2011-01-01

    Full Text Available DNA vaccines showed great promise in preclinical models of infectious and malignant diseases, but their potency was insufficient in clinical trials and is needed to be improved. In this study, we tested systemic administration of two conventional adjuvants, synthetic oligodeoxynucleotide carrying immunostimulatory CpG motifs (CpG-ODN and levamisole (LMS, and evaluated their effect on immune reactions induced by DNA vaccines delivered by a gene gun. DNA vaccination was directed either against the E7 oncoprotein of human papillomavirus type 16 or against the BCR-ABL1 oncoprotein characteristic for chronic myeloid leukemia. High doses of both adjuvants reduced activation of mouse splenic CD8+ T lymphocytes, but the overall antitumor effect was enhanced in both tumor models. High-dose CpG-ODN exhibited a superior adjuvant effect in comparison with any combination of CpG-ODN with LMS. In summary, our results demonstrate the benefit of combined therapy with gene-gun-delivered antitumor DNA vaccines and systemic administration of CpG-ODN or LMS.

  15. Hand-held tidal breathing nasal nitric oxide measurement--a promising targeted case-finding tool for the diagnosis of primary ciliary dyskinesia.

    Directory of Open Access Journals (Sweden)

    June Kehlet Marthin

    Full Text Available BACKGROUND: Nasal nitric oxide (nNO measurement is an established first line test in the work-up for primary ciliary dyskinesia (PCD. Tidal breathing nNO (TB-nNO measurements require minimal cooperation and are potentially useful even in young children. Hand-held NO devices are becoming increasingly widespread for asthma management. Therefore, we chose to assess whether hand-held TB-nNO measurements reliably discriminate between PCD, and Healthy Subjects (HS and included Cystic Fibrosis (CF patients as a disease control group known to have intermediate nNO levels. METHODS: In this cross sectional, single centre, single occasion, proof-of-concept study in children and adults with PCD and CF, and in HS we compared feasibility, success rates, discriminatory capacity, repeatability and agreement between a hand-held electrochemical device equipped with a nNO software application sampling at flow rates 2 ml/s or 5 ml/s, and two stationary chemiluminescence devices, applying both tidal breathing and velum closure techniques. RESULTS: Measurements were done in 16 PCD patients, 21 patients with CF and 20 HS aged between 3.8 and 60.9 years. Hand-held TB-nNO showed high success rate (96.5-100% vs. velum closure nNO techniques (70.2-89.5%. Hand-held TB-nNO sampling at flow rate 5 ml/s showed equally high discriminative power (PCD vs. HS [p<0.0001] and PCD vs. CF [p<0.0001] and reaching close to 100% sensitivity and specificity, superior repeatability (CV% = 10% and equal limits of agreement compared to TB-nNO by stationary devices and even compared to velum closure sampling. CONCLUSION: Hand-held TB-nNO discriminates significantly between PCD, CF and HS and shows promising potential as a widespread targeted case-finding tool for PCD, although further studies are warranted before implementation.

  16. 基于用户需求的家用电动工具造型设计研究%Research on Household Hand-held Electric Tools Sculpting Design Based on User Demand

    Institute of Scientific and Technical Information of China (English)

    李刚

    2015-01-01

    基于产品造型设计相关理论,在功能、美学和经济性要求的基础上,分析探讨多学科优化设计原理、系列化设计原理、产品基因原理与协同设计等原则应用于家庭用手持式电动工具系列产品,并进行实例设计.%Based on the related theory of sculpting design and on the basis of function, aesthetic and economic requirements, analyze and discuss the multidisciplinary optimization design principle, series design principle, product gene principle and collaborative design principle, applying to household hand-held power tool series products and instantiate the design.

  17. Hand-held tidal breathing nasal nitric oxide measurement--a promising targeted case-finding tool for the diagnosis of primary ciliary dyskinesia

    DEFF Research Database (Denmark)

    Marthin, June Kehlet; Nielsen, Kim Gjerum

    2013-01-01

    BACKGROUND: Nasal nitric oxide (nNO) measurement is an established first line test in the work-up for primary ciliary dyskinesia (PCD). Tidal breathing nNO (TB-nNO) measurements require minimal cooperation and are potentially useful even in young children. Hand-held NO devices are becoming...... at flow rates 2 ml/s or 5 ml/s, and two stationary chemiluminescence devices, applying both tidal breathing and velum closure techniques. RESULTS: Measurements were done in 16 PCD patients, 21 patients with CF and 20 HS aged between 3.8 and 60.9 years. Hand-held TB-nNO showed high success rate (96...

  18. Assessment of nickel and cobalt release from 200 unused hand-held work tools for sale in Denmark — Sources of occupational metal contact dermatitis?

    DEFF Research Database (Denmark)

    Thyssen, Jacob P.; Jensen, Peter; Lidén, Carola

    2011-01-01

    tools for sale in 2 retailers of home improvement and construction products were analyzed qualitatively for metal release using the colorimetric nickel and cobalt spot tests. ResultsNickel release was identified from 5% of 200 work tools using the dimethylglyoxime (DMG) test. In 8 of 10, positive......IntroductionNickel and cobalt allergy remain frequent in dermatitis patients. It is important to determine possible nickel and cobalt exposures at work as these may offer important information to regulators and physicians who perform patch testing. Clinical relevance of metal exposure is usually...... assessed by the treating physician via the medical history and by presentation of allergic contact dermatitis. ObjectivesTo screen unused non-powered hand-held work tools for nickel and cobalt release by using colorimetric spot tests. Materials & methodsA random selection of 200 non-powered hand-held work...

  19. A functional polymorphism in a serotonin transporter gene (5-HTTLPR) interacts with 9/11 to predict gun-carrying behavior.

    Science.gov (United States)

    Barnes, J C; Beaver, Kevin M; Boutwell, Brian B

    2013-01-01

    On September 11, 2001, one of the deadliest terrorist attacks in US history took place on American soil and people around the world were impacted in myriad ways. Building on prior literature which suggests individuals are more likely to purchase a gun for self-protection if they are fearful of being victimized, the authors hypothesized that the terrorist attacks of 9/11 would lead to an increase in gun carrying among US residents. At the same time, a line of research has shown that a polymorphism in the 5-HTT gene (i.e., 5-HTTLPR) interacts with environmental stressors to predict a range of psychopathologies and behaviors. Thus, it was hypothesized that 9/11 and 5-HTTLPR would interact to predict gun carrying. The results supported both hypotheses by revealing a positive association between 9/11 and gun carrying (b = .426, odds ratio = 1.531, standard error for b = .194, z = 2.196, p = .028) in the full sample of respondents (n = 15,052) and a statistically significant interaction between 9/11 and 5-HTTLPR in the prediction of gun carrying (b = -1.519, odds ratio = .219, standard error for b = .703, z = -2.161, p = .031) in the genetic subsample of respondents (n = 2,350). This is one of the first studies to find an association between 9/11 and gun carrying and, more importantly, is the first study to report a gene-environment interaction (GxE) between a measured gene and a terrorist attack.

  20. A functional polymorphism in a serotonin transporter gene (5-HTTLPR interacts with 9/11 to predict gun-carrying behavior.

    Directory of Open Access Journals (Sweden)

    J C Barnes

    Full Text Available On September 11, 2001, one of the deadliest terrorist attacks in US history took place on American soil and people around the world were impacted in myriad ways. Building on prior literature which suggests individuals are more likely to purchase a gun for self-protection if they are fearful of being victimized, the authors hypothesized that the terrorist attacks of 9/11 would lead to an increase in gun carrying among US residents. At the same time, a line of research has shown that a polymorphism in the 5-HTT gene (i.e., 5-HTTLPR interacts with environmental stressors to predict a range of psychopathologies and behaviors. Thus, it was hypothesized that 9/11 and 5-HTTLPR would interact to predict gun carrying. The results supported both hypotheses by revealing a positive association between 9/11 and gun carrying (b = .426, odds ratio = 1.531, standard error for b = .194, z = 2.196, p = .028 in the full sample of respondents (n = 15,052 and a statistically significant interaction between 9/11 and 5-HTTLPR in the prediction of gun carrying (b = -1.519, odds ratio = .219, standard error for b = .703, z = -2.161, p = .031 in the genetic subsample of respondents (n = 2,350. This is one of the first studies to find an association between 9/11 and gun carrying and, more importantly, is the first study to report a gene-environment interaction (GxE between a measured gene and a terrorist attack.

  1. Demonstration of the B4C/NaIO4/PTFE Delay in the U.S. Army Hand-Held Signal

    Science.gov (United States)

    2015-05-20

    KEYWORDS: Pyrotechnic delay, Boron carbide, Periodate, Hand-held signal, Sustainable chemistry ■ INTRODUCTION Pyrotechnic delays provide controlled...UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Armament Research, Development and Engineering Center, U.S. Army RDECOM-ARDEC...Picatinny Arsenal, New Jersey 07806, United States 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10

  2. Development and Performance of the W/Sb2O3/KIO4/Lubricant Pyrotechnic Delay in the US Army Hand-Held Signal

    Science.gov (United States)

    2013-01-01

    were obtained from Sigma Aldrich. Stearic acid (19–5010) was obtained from Hummel Croton. A Malvern Morphologi G3S optical micros- copy particle size...35 – 40 Full Paper J. C. Poret, A. P. Shaw, C. M. Csernica, K. D. Oyler, D. P. Estes equipped with a secondary electron imaging ( SEI ) detector. The...an ongoing area of research in our laboratories. Symbols and Abbreviations HHS Hand-held signal SEM Scanning electron microscopy SEI Secondary

  3. Improving the accuracy of hand-held X-ray fluorescence spectrometers as a tool for monitoring brominated flame retardants in waste polymers.

    Science.gov (United States)

    Guzzonato, A; Puype, F; Harrad, S J

    2016-09-01

    An optimised method for Br quantification as a metric of brominated flame retardant (BFR) concentrations present in Waste Electrical and Electronic Equipment (WEEE) polymers is proposed as an alternative to the sophisticated, yet time consuming GC-MS methods currently preferred. A hand-held X-ray fluorescence (XRF) spectrometer was validated with Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS). Customized standard materials of specific BFRs in a styrenic polymer were used to perform an external calibration for hand-held XRF ranging from 0.08 to 12 wt% of Br, and cross-checking with LA-ICP-MS having similar LODs (0.0004 wt% for LA-ICP-MS and 0.0011 wt% for XRF). The "thickness calibration" developed here for hand-held XRF and the resulting correction, was applied to 28 real samples and showed excellent (R(2) = 0.9926) accordance with measurements obtained via LA-ICP-MS. This confirms the validity of hand-held XRF as an accurate technique for the determination of Br in WEEE plastics. This is the first use of solid standards to develop a thickness-corrected quantitative XRF measurement of Br in polymers using LA-ICP-MS for method evaluation. Thermal desorption gas chromatography mass spectrometry (TD-GC-MS) was used to confirm the presence of specific BFRs in WEEE polymer samples. We propose that expressing limit values for BFRs in waste materials in terms of Br rather than BFR concentration (based on a conservative assumption about the BFR present), presents a practical solution to the need for an accurate, yet rapid and inexpensive technique capable of monitoring compliance with limit values in situ.

  4. Evaluation of U.S. Commercial-Off-the-Shelf Hand-Held Assays to Detect Opiate Pain Reliever Compounds in Multiple Biofluids

    Science.gov (United States)

    2016-09-01

    Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to any penalty for fa iling to comply with a...abused for their intense euphoric effects and unfortunately, result in frequent cases of overdose, respiratory depression, and death . Based on...States caused 36,450 deaths and OPRs were involved in 14,800 of those deaths (73.8%).2 There is currently no fielded, validated hand-held assay

  5. Fusion of a viral antigen to invariant chain leads to augmented T-cell immunity and improved protection in gene-gun DNA-vaccinated mice

    DEFF Research Database (Denmark)

    Grujic, Mirjana; Holst, Peter J; Christensen, Jan P

    2009-01-01

    against lethal peripheral challenge. The current study questioned whether the same strategy, i.e. linkage of GP to an Ii chain, could be applied to a naked DNA vaccine. Following gene-gun immunization with the linked construct (DNA-IiGP), GP-specific CD4(+) T cells could not be detected by flow cytometry...

  6. Intra- and inter-rater reliability of isometric shoulder extensor and internal rotator strength measurements performed using a hand-held dynamometer.

    Science.gov (United States)

    Awatani, Takenori; Morikita, Ikuhiro; Shinohara, Junji; Mori, Seigo; Nariai, Miki; Tatsumi, Yasutaka; Nagata, Akinori; Koshiba, Hiroya

    2016-11-01

    [Purpose] The purpose of the present study was to establish the intra- and inter-rater reliability of measurement of extensor strength in the maximum shoulder abducted position and internal rotator strength in the 90° abducted and the 90° external rotated position using a hand-held dynamometer. [Subjects and Methods] Twelve healthy volunteers (12 male; mean ± SD: age 19.0 ± 1.1 years) participated in the study. The examiners were two students who had nonclinical experience with a hand-held dynamometer measurement. The examiners and participants were blinded to measurement results by the recorder. Participants in the prone position were instructed to hold the contraction against the ground reaction force, and peak isometric force was recorded using the hand-held dynamometer on the floor. Reliability was determined using intraclass correlation coefficients. [Results] The intra- and inter-rater reliability data were found to be "almost perfect". [Conclusion] This study investigated intra- and inter-rater reliability and reveald high reliability. Thus, the measurement method used in the present study can evaluate muscle strength by a simple measurement technique.

  7. Gun Control, Gun Ownership, and Suicide Prevention.

    Science.gov (United States)

    Lester, David

    1988-01-01

    Explored relationship between the extent of gun ownership and the strictness of gun control laws to suicide and homicide rates in the nine major geographic regions of the United States. Found gun ownership, rather than the strictness of gun control laws, was the strongest correlate of the rates of suicide and homicide by guns. (Author)

  8. Myostatin propeptide gene delivery by gene gun ameliorates muscle atrophy in a rat model of botulinum toxin-induced nerve denervation.

    Science.gov (United States)

    Tsai, Sen-Wei; Tung, Yu-Tang; Chen, Hsiao-Ling; Yang, Shang-Hsun; Liu, Chia-Yi; Lu, Michelle; Pai, Hui-Jing; Lin, Chi-Chen; Chen, Chuan-Mu

    2016-02-01

    Muscle atrophy is a common symptom after nerve denervation. Myostatin propeptide, a precursor of myostatin, has been documented to improve muscle growth. However, the mechanism underlying the muscle atrophy attenuation effects of myostatin propeptide in muscles and the changes in gene expression are not well established. We investigated the possible underlying mechanisms associated with myostatin propeptide gene delivery by gene gun in a rat denervation muscle atrophy model, and evaluated gene expression patterns. In a rat botulinum toxin-induced nerve denervation muscle atrophy model, we evaluated the effects of wild-type (MSPP) and mutant-type (MSPPD75A) of myostatin propeptide gene delivery, and observed changes in gene activation associated with the neuromuscular junction, muscle and nerve. Muscle mass and muscle fiber size was moderately increased in myostatin propeptide treated muscles (pmuscle regulatory factors, neurite outgrowth factors (IGF-1, GAP43) and acetylcholine receptors was observed. Our results demonstrate that myostatin propeptide gene delivery, especially the mutant-type of MSPPD75A, attenuates muscle atrophy through myogenic regulatory factors and acetylcholine receptor regulation. Our data concluded that myostatin propeptide gene therapy may be a promising treatment for nerve denervation induced muscle atrophy. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. A convenient cancer vaccine therapy with in vivo transfer of interleukin 12 expression plasmid using gene gun technology after priming with irradiated carcinoma cells.

    Science.gov (United States)

    Nishitani, Masa-aki; Sakai, Tohru; Ishii, Kazunari; Zhang, Manxin; Nakano, Yoko; Nitta, Yoshio; Miyazaki, Jun-ichi; Kanayama, Hiro-omi; Kagawa, Susumu; Himeno, Kunisuke

    2002-02-01

    We studied interleukin (IL)-12 gene therapy using a gene gun as a new autologous vaccination strategy for cancer. In the first experiment, BALB/c mice were inoculated with syngeneic murine renal cancer cells (Renca) intradermally in the abdomen. This was followed by an injection of IL-12 expression plasmid using the gene gun. About 40% of the mice exhibited rejection of the tumor after the treatment and these mice also acquired immunological resistance against a secondary challenge with Renca cells. Based on these results, we examined whether antitumor activity can be potentiated when mice undergo combination treatment with intradermal inoculation of irradiated Renca cells and transfection with IL-12 gene. Inoculation of irradiated Renca cells alone was partially effective in inducing antitumor immunity, whereas the combined treatment remarkably intensified this effect. Moreover, this combined treatment inhibited tumor establishment and enhanced survival of the mice with tumor infiltration by CD4(+) and CD8(+) T cells, even when the treatment was started after tumor-implantation at a distant site. This antitumor effect was antigen specific and we confirmed the induction of antitumor cytotoxic T cells by this treatment. These results show that local cutaneous transfer of IL-12 expression plasmid using gene gun technology enhances systemic and specific antitumor immunity primed by irradiated tumor cells.

  10. Portable computing for taking part of the lab to the sample types of applications. From hand held personal digital assistants to smart phones for mobile spectrometry

    Science.gov (United States)

    Weagant, Scott; Karanassios, Vassili

    2015-06-01

    The use of portable hand held computing devices for the acquisition of spectrochemical data is briefly discussed using examples from the author's laboratory. Several network topologies are evaluated. At present, one topology that involves a portable computing device for data acquisition and spectrometer control and that has wireless access to the internet at one end and communicates with a smart phone at the other end appears to be better suited for "taking part of the lab to the sample" types of applications. Thus, spectrometric data can be accessed from anywhere in the world.

  11. (abstract) Applications of Long-wavelength 256x256 GaAs/Al&subx;Ga&sub1-x;As Quantum Well Infrared Photodetector Hand-held Camera

    Science.gov (United States)

    Gunapala, S. D.; Bandara, S. V.; Liu, J. K.; Sundaram, M.; Hong, W.; Shott, C. A.; Hoelter, T.; Laband, S.; James, J. B.

    1997-01-01

    A 9 (micro)m 256x256 hand-held quantum well infrared photodetector (QWIP) camera has been demonstrated. Excellent imagery, with a noise equivalent differential temperature (NE(gamma)) of 26 mK has been achieved. In this presentation, we discuss the development of this very sensitive long wavelength infrared (LWIR) camera based on a GaAs/AlGaAs QWIP focal plane array, its performance in quantum efficience, NA(gamma), minimum resolvable temperature (MRTD), uniformity, operability, and its applications.

  12. Hand-Held Femtogram Detection of Hazardous Picric Acid with 2 Hydrophobic Ag Nanopillar SERS Substrates and Mechanism of 3 Elasto-Capillarity

    DEFF Research Database (Denmark)

    Hakonen, Aron; Wang, FengChao; Andersson, Per Ola

    2017-01-01

    surface-enhanced Raman scattering (SERS) silver nanopillar substrates and hand-held Raman spectroscopy equipment. The advancing elasto-capillarity effects are explained by molecular dynamics simulations. We obtain a SERS PA detection limit on the order of 20 ppt, corresponding attomole amounts, which......Picric acid (PA) is a severe environmental and security risk due to its unstable, toxic, and explosive properties. It is also challenging to detect in trace amounts and in situ because of its highly acidic and anionic character. Here, we assess sensing of PA under nonlaboratory conditions using...

  13. Spectrometer gun

    Science.gov (United States)

    Waechter, David A.; Wolf, Michael A.; Umbarger, C. John

    1985-01-01

    A hand-holdable, battery-operated, microprocessor-based spectrometer gun includes a low-power matrix display and sufficient memory to permit both real-time observation and extended analysis of detected radiation pulses. Universality of the incorporated signal processing circuitry permits operation with various detectors having differing pulse detection and sensitivity parameters.

  14. Establishment of transgenic acceptor and transformation of barnase gene by particle gun in maize inbred line 18-599(white)

    Institute of Scientific and Technical Information of China (English)

    Qingquan SUN; Ying ZHANG; Tingzhao RONG; Shuting DONG; Dengchao MA; Chunqing ZHANG

    2008-01-01

    The efficient acceptors for maize transgenic engineering are currently insufficient in China. Seed production by male sterility is the best method for advancing the authenticity of maize hybrid. Maize inbred line 18-599 (white) is an antivirus high-quality maize inbred line in China, which has been used for lots of maize hybrid cultivars. The establishment of high efficiency transgenic acceptors is necessary for advancing the transgenic efficiency in maize transformation work. In this study, the efficient transgenic acceptors were optimized and established. 18-599 (white) was studied in state, types of culture mediums, times of callus regen-eration and concentration of the screening reagent, Basta. The results showed that N6-4 medium was the best in 8 types of mediums for the immature embryo of 18-599 (white), 1.6 mm length was the feasible length of immature embryos for tissue culture in establishing the transgenic acceptor system, and it was within 5 times for suitable callus subculture. With the optimized transgenic acceptors, barnase gene was translated successfully into 18-599 (white) by a particle gun using bar as a marker gene. Basta was used as the screening reagent, its lethal callus regeneration, respectively. In this work, a trans-genic plant with male sterility was obtained through molecule detection and observation in the field. The result has an important significance for the creation of new male sterility inbred lines in maize in the future.

  15. Motion-compensated hand-held common-path Fourier-domain optical coherence tomography probe for image-guided intervention

    Science.gov (United States)

    Huang, Yong; Song, Cheol; Liu, Xuan; Kang, Jin U.

    2013-03-01

    A motion-compensated hand-held common-path Fourier-domain optical coherence tomography imaging probe has been developed for image guided intervention during microsurgery. A hand-held prototype instrument was designed and fabricated by integrating an imaging fiber probe inside a stainless steel needle which is attached to the ceramic shaft of a piezoelectric motor housed in an aluminum handle. The fiber probe obtains A-scan images. The distance information was extracted from the A-scans to track the sample surface distance and a fixed distance was maintained by a feedback motor control which effectively compensated hand tremor and target movements in the axial direction. Graphical user interface, real-time data processing, and visualization based on a CPU-GPU hybrid programming architecture were developed and used in the implantation of this system. To validate the system, free-hand optical coherence tomography images using various samples were obtained. The system can be easily integrated into microsurgical tools and robotics for a wide range of clinical applications. Such tools could offer physicians the freedom to easily image sites of interest with reduced risk and higher image quality.

  16. Into the Wild: Neuroergonomic Differentiation of Hand-Held and Augmented Reality Wearable Displays during Outdoor Navigation with Functional Near Infrared Spectroscopy.

    Science.gov (United States)

    McKendrick, Ryan; Parasuraman, Raja; Murtza, Rabia; Formwalt, Alice; Baccus, Wendy; Paczynski, Martin; Ayaz, Hasan

    2016-01-01

    Highly mobile computing devices promise to improve quality of life, productivity, and performance. Increased situation awareness and reduced mental workload are two potential means by which this can be accomplished. However, it is difficult to measure these concepts in the "wild". We employed ultra-portable battery operated and wireless functional near infrared spectroscopy (fNIRS) to non-invasively measure hemodynamic changes in the brain's Prefrontal cortex (PFC). Measurements were taken during navigation of a college campus with either a hand-held display, or an Augmented reality wearable display (ARWD). Hemodynamic measures were also paired with secondary tasks of visual perception and auditory working memory to provide behavioral assessment of situation awareness and mental workload. Navigating with an augmented reality wearable display produced the least workload during the auditory working memory task, and a trend for improved situation awareness in our measures of prefrontal hemodynamics. The hemodynamics associated with errors were also different between the two devices. Errors with an augmented reality wearable display were associated with increased prefrontal activity and the opposite was observed for the hand-held display. This suggests that the cognitive mechanisms underlying errors between the two devices differ. These findings show fNIRS is a valuable tool for assessing new technology in ecologically valid settings and that ARWDs offer benefits with regards to mental workload while navigating, and potentially superior situation awareness with improved display design.

  17. Hand-held high-resolution fluorescence imaging system for fluorescence-guided surgery of patient and cell-line pancreatic tumors growing orthotopically in nude mice.

    Science.gov (United States)

    Hiroshima, Yukihiko; Maawy, Ali; Sato, Sho; Murakami, Takashi; Uehara, Fuminari; Miwa, Shinji; Yano, Shuya; Momiyama, Masashi; Chishima, Takashi; Tanaka, Kuniya; Bouvet, Michael; Endo, Itaru; Hoffman, Robert M

    2014-04-01

    In this study, we investigated the advantages of fluorescence-guided surgery (FGS) in mice of a portable hand-sized imaging system compared with a large fluorescence imaging system or a long-working-distance fluorescence microscope. Mouse models of human pancreatic cancer for FGS included the following: (1) MiaPaCa-2-expressing green fluorescent protein, (2) BxPC3 labeled with Alexa Fluor 488-conjucated anti-carcinoembryonic antigen (CEA) antibody, and (3) patient-derived orthotopic xenograft (PDOX) labeled with Alexa Fluor 488-conjugated anti-carbohydrate antigen 19-9 antibody. Each device could clearly detect the primary MiaPaCa-2-green fluorescent protein tumor and any residual tumor after FGS. In the BxPC3 model labeled with Alexa Fluor 488-conjugated anti-CEA, each device could detect the primary tumor, but the MVX10 could not clearly detect the residual tumor remaining after FGS whereas the other devices could. In the PDOX model labeled with Alexa Fluor 488-conjugated anti-carbohydrate antigen 19-9, only the portable hand-held device could distinguish the residual tumor from the background, and complete resection of the residual tumor was achieved under fluorescence navigation. The results described in the present report suggest that the hand-held mobile imaging system can be applied to the clinic for FGS because of its convenient size and high sensitivity which should help make FGS widely used. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. Water gun vs air gun: A comparison

    Science.gov (United States)

    Hutchinson, D.R.; Detrick, R. S.

    1984-01-01

    The water gun is a relatively new marine seismic sound source that produces an acoustic signal by an implosive rather than explosive mechanism. A comparison of the source characteristics of two different-sized water guns with those of conventional air guns shows the the water gun signature is cleaner and much shorter than that of a comparable-sized air gun: about 60-100 milliseconds (ms) for an 80-in3. (1.31-liter (I)) water gun compared with several hundred ms for an 80-in3. (1.31-1) air gun. The source spectra of water guns are richer in high frequencies (>200 Hz) than are those of air guns, but they also have less energy than those of air guns at low frequencies. A comparison between water gun and air gun reflection profiles in both shallow (Long Island Sound)-and deep (western Bermuda Rise)-water settings suggests that the water gun offers a good compromise between very high resolution, limited penetration systems (e.g. 3.5-kHz profilers and sparkers) and the large volume air guns and tuned air gun arrays generally used where significant penetration is required. ?? 1984 D. Reidel Publishing Company.

  19. Immune Reactions against Gene Gun Vaccines Are Differentially Modulated by Distinct Dendritic Cell Subsets in the Skin.

    Directory of Open Access Journals (Sweden)

    Corinna Stefanie Weber

    Full Text Available The skin accommodates multiple dendritic cell (DC subsets with remarkable functional diversity. Immune reactions are initiated and modulated by the triggering of DC by pathogen-associated or endogenous danger signals. In contrast to these processes, the influence of intrinsic features of protein antigens on the strength and type of immune responses is much less understood. Therefore, we investigated the involvement of distinct DC subsets in immune reactions against two structurally different model antigens, E. coli beta-galactosidase (betaGal and chicken ovalbumin (OVA under otherwise identical conditions. After epicutaneous administration of the respective DNA vaccines with a gene gun, wild type mice induced robust immune responses against both antigens. However, ablation of langerin+ DC almost abolished IgG1 and cytotoxic T lymphocytes against betaGal but enhanced T cell and antibody responses against OVA. We identified epidermal Langerhans cells (LC as the subset responsible for the suppression of anti-OVA reactions and found regulatory T cells critically involved in this process. In contrast, reactions against betaGal were not affected by the selective elimination of LC, indicating that this antigen required a different langerin+ DC subset. The opposing findings obtained with OVA and betaGal vaccines were not due to immune-modulating activities of either the plasmid DNA or the antigen gene products, nor did the differential cellular localization, size or dose of the two proteins account for the opposite effects. Thus, skin-borne protein antigens may be differentially handled by distinct DC subsets, and, in this way, intrinsic features of the antigen can participate in immune modulation.

  20. Gun Safety (For Parents)

    Science.gov (United States)

    ... Teaching Kids to Be Smart About Social Media Gun Safety KidsHealth > For Parents > Gun Safety Print A ... unloaded, and the ammunition should be stored separately. Guns and Pretend Play Allowing kids to play with ...

  1. 基于Android的定位追踪APP的设计与实现%The Design of Simple Hand-held Tracking APP Based on Android

    Institute of Scientific and Technical Information of China (English)

    葛欣; 蔺雪葳; 王依岳

    2016-01-01

    针对手持定位追踪器便携及操作方面的缺陷,本文设计了基于Android的追踪器手机客户端APP。从定位系统的完整性出发,介绍了追踪系统的工作原理、服务器端数据处理机制、手机APP工作流程,以及调用百度地图显示定位器位置的原理和流程。%Defect Tracker for portable hand-held and operated, this article is designed based on Android tracking client APP, from the integrity of the positioning system, the working principle of the tracking system, server-side data processing mechanism, the mobile phone APP workflow and call Baidu map shows the location of the vehicle the principles and processes.

  2. Encyclopedia of Gun Control and Gun Rights.

    Science.gov (United States)

    Utter, Glenn H.

    This reference volume provides information on gun control and gun rights, including resources on the debate surrounding the Second Amendment and individuals and organizations focused on gun issues, along with statutes, court cases, events, and publications surrounding this current topic. Highlighted are the important organizations and their…

  3. Gun ownership and social gun culture.

    Science.gov (United States)

    Kalesan, Bindu; Villarreal, Marcos D; Keyes, Katherine M; Galea, Sandro

    2016-06-01

    We assessed gun ownership rates in 2013 across the USA and the association between exposure to a social gun culture and gun ownership. We used data from a nationally representative sample of 4000 US adults, from 50 states and District of Columbia, aged >18 years to assess gun ownership and social gun culture performed in October 2013. State-level firearm policy information was obtained from the Brady Law Center and Injury Prevention and Control Center. One-third of Americans reported owning a gun, ranging from 5.2% in Delaware to 61.7% in Alaska. Gun ownership was 2.25-times greater among those reporting social gun culture (PR=2.25, 95% CI 2.02 to 2.52) than those who did not. In conclusion, we found strong association between social gun culture and gun ownership. Gun cultures may need to be considered for public health strategies that aim to change gun ownership in the USA. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  4. ION GUN

    Science.gov (United States)

    Dandl, R.A.

    1961-10-24

    An ion gun is described for the production of an electrically neutral ionized plasma. The ion gun comprises an anode and a cathode mounted in concentric relationship with a narrow annulus between. The facing surfaces of the rear portions of the anode and cathode are recessed to form an annular manifold. Positioned within this manifold is an annular intermediate electrode aligned with the an nulus between the anode and cathode. Gas is fed to the manifold and an arc discharge is established between the anode and cathode. The gas is then withdrawn from the manifold through the annulus between the anode and cathode by a pressure differential. The gas is then ionized by the arc discharge across the annulus. The ionized gas is withdrawn from the annulus by the combined effects of the pressure differential and a collimating magnetic field. In a 3000 gauss magnetic field, an arc voltage of 1800 volts, and an arc current of 0.2 amp, a plasma of about 3 x 10/sup 11/ particles/cc is obtained. (AEC)

  5. ELECTRON GUN

    Science.gov (United States)

    Christofilos, N.C.; Ehlers, K.W.

    1960-04-01

    A pulsed electron gun capable of delivering pulses at voltages of the order of 1 mv and currents of the order of 100 amperes is described. The principal novelty resides in a transformer construction which is disposed in the same vacuum housing as the electron source and accelerating electrode structure of the gun to supply the accelerating potential thereto. The transformer is provided by a plurality of magnetic cores disposed in circumferentially spaced relation and having a plurality of primary windings each inductively coupled to a different one of the cores, and a helical secondary winding which is disposed coaxially of the cores and passes therethrough in circumferential succession. Additional novelty resides in the disposition of the electron source cathode filament input leads interiorly of the transformer secondary winding which is hollow, as well as in the employment of a half-wave filament supply which is synchronously operated with the transformer supply such that the transformer is pulsed during the zero current portions of the half-wave cycle.

  6. In vitro analysis of SERCA2 gene regulation in hypertrophic cardiomyocytes and increasing transfection efficiency by gene-gun biolistics

    NARCIS (Netherlands)

    K. Eizema (Karin); H.A. van Heugten (Han); K. Bezstarosti (Karel); M.C. van Setten (Marga); J.M.J. Lamers (Jos)

    1999-01-01

    textabstractThe transcriptional downregulation of the SERCA2 gene is studied using neonatal rat cardiomyocytes stimulated with endothelin-1 to induce hypertrophy. Liposome-based transfection of cells with a 1.9 kb SERCA2 promoter fragment directed expression of a reporter gene identical to the downr

  7. The Gun Violence Database

    OpenAIRE

    Pavlick, Ellie; Callison-Burch, Chris

    2016-01-01

    We describe the Gun Violence Database (GVDB), a large and growing database of gun violence incidents in the United States. The GVDB is built from the detailed information found in local news reports about gun violence, and is constructed via a large-scale crowdsourced annotation effort through our web site, http://gun-violence.org/. We argue that centralized and publicly available data about gun violence can facilitate scientific, fact-based discussion about a topic that is often dominated by...

  8. Enhancement of soil DNA extraction by the use of a hand held mixer Otimização da extração de DNA do solo utilizando um homogeneizador manual

    Directory of Open Access Journals (Sweden)

    Jefferson Luis da Silva Costa

    2003-12-01

    Full Text Available The efficiency of soil DNA extraction using a bead beater homogenizer (Biospec Products - Germany was compared to that obtained with a hand held mixer (Moulinex - Brazil. The hand held mixer costs 100 times less and extracted seven times more crude DNA than the bead beater.A eficiência da extração de DNA do solo utilizando um homogeneizador bead beater (Biospec Products - Alemanha foi comparada àquela obtida utilizando um homogeneizador manual (Moulinex - Brasil. O homogeneizador manual tem custo 100 vezes menor e revelou-se mais eficiente que o bead beater extraindo sete vezes mais DNA.

  9. Design of hand-held digital oscilloscope based on FPGA%基于 FPGA 的手持式数字示波器的设计∗

    Institute of Scientific and Technical Information of China (English)

    朱詠筠; 易艺; 郝建卫; 李俊凯; 王奕澄

    2015-01-01

    According to the weakness of traditional oscilloscope problems such as large volume and inconvenience,the project base on FPGA (Field Programmable Gate Array ) strong performance to develop a hand-held digital oscilloscope.The system use Altera FPGA as the main control chip to design a logic control circuit.And it use the Quartus II development tools and Verilog HDL language to describe the functions such as control logic, clock distribution,sampling buffer,trigger,frequency and amplitude measuring,etc.System design the SOPC Builder to build the Nios II soft core processor,and it through the C language programming to realize the touch control,display control functions.The test result shows that the oscilloscope system work is stable,and it has high performance and practicality.The project has reference value in the research of the hand-held digital oscilloscope.%针对传统示波器体积大、携带不便等问题,利用现场可编程门阵列(field programmable gate array,FPGA)强大的性能,研制一款基于 FPGA 的手持式数字示波器。系统以 Altera 公司 FPGA 为主控芯片组建逻辑控制电路,利用 Quartus II 开发工具以及 Verilog HDL 语言描述控制逻辑,实现时钟分配、采样缓冲、触发、测频、测幅等功能。用SOPC Builder 构建 Nios II 软核处理器,通过 C 语言编程实现触摸控制、显示控制等功能。经过实验测试表明,该示波器系统工作稳定,具有较高的性能指标和实用性,在手持式数字示波器的研制方面有较好的参考价值。

  10. Hand-Held UXO Discriminator

    Science.gov (United States)

    2010-04-01

    studies also included various capacitors , resistors, damping factors and coupling in both the S and T-termination modes. The accuracy of the model...be used as follows: (1) teflon, (2) polypropylene , (3) polystyrene, (4) polyethylene (foam is better than solid). 2.4 Fabrication and assembly...shields several different ways as well. These included floating ground, grounded to the data acquisition board, grounded to 24 V capacitor , with

  11. Hand-held survey probe

    Science.gov (United States)

    Young, Kevin L [Idaho Falls, ID; Hungate, Kevin E [Idaho Falls, ID

    2010-02-23

    A system for providing operational feedback to a user of a detection probe may include an optical sensor to generate data corresponding to a position of the detection probe with respect to a surface; a microprocessor to receive the data; a software medium having code to process the data with the microprocessor and pre-programmed parameters, and making a comparison of the data to the parameters; and an indicator device to indicate results of the comparison. A method of providing operational feedback to a user of a detection probe may include generating output data with an optical sensor corresponding to the relative position with respect to a surface; processing the output data, including comparing the output data to pre-programmed parameters; and indicating results of the comparison.

  12. Reliability of Isometric Knee Extension Muscle Strength Measurements of Healthy Elderly Subjects Made with a Hand-held Dynamometer and a Belt.

    Science.gov (United States)

    Katoh, Munenori; Isozaki, Koji

    2014-12-01

    [Purpose] The purpose of this study was to examine the reliability of three isometric knee extension strength measurements (IKE) made with a hand-held dynamometer (HHD) and a belt of healthy elderly living in the community as subjects. [Subjects] The subject cohort consisted of 186 healthy elderly people, aged 65 to 79 years, living in local communities. [Methods] IKE of the leg subjects used to kick a ball was measured. IKE of each subject was measured three times using an HHD-belt at intervals of 30 seconds. The reliability of the larger of the first two measurements (LV2) as well as the third measurement (3V) was investigated. [Results] The intraclass correlation coefficients [ICC (1, 1)] for LV2 and 3V were 0.955. Bland-Altman analysis showed a fixed bias, and the limits of agreement ranged from -5.6 to 4.6. [Conclusion] The ICC results show that the test-retest reproducibility of IKE measurements of healthy elderly subjects using an HHD-belt is high. However, Bland-Altman analysis showed a fixed bias, suggesting the need for three measurements.

  13. Inter-tester Reliability of the Hand-held dynamometer and the Leg Extensor Power Rig applied on Patients after Total Hip Arthroplasty

    DEFF Research Database (Denmark)

    Mikkelsen, Lone Ramer; Mechlenburg, Inger; Petersen, Annemette Krintel

    INTRODUCTION: Rehabilitation has an increasing focus on intensive resistance training early after joint replacement (1,2). This increases the requests for measuring changes in the muscle strength and muscle power over time. Hand-held dynamometer (HHD) is a device used to measure isometric muscle...... strength and Leg Extensor Power Rig (LEPR) is a tool for measuring muscle power. OBJECTIVES: To test the inter-tester reliability of the HHD in hip abduction and the LEPR in Total Hip Arthroplasty (THA) patients. METHODS: Two groups each consisting 20 subjects were included. Mean age was 68.4 years. All...... the two testers (p=0.62) and the two tests (0.14); ICC=0.91 (95% CI: 0.79;0.96); LOA=±34Watt. CONCLUSION: The relative reliability was acceptable for both HHD and LEPR. The absolute reliability showed that a change in the muscle strength/power above 18 Newton or 34 Watt can be counted as a real change...

  14. Inter-tester Reliability of the Hand-held dynamometer and the Leg Extensor Power Rig applied on Patients after Total Hip Arthroplasty

    DEFF Research Database (Denmark)

    Mikkelsen, Lone Ramer; Petersen, Annemette Krintel; Mikkelsen, Søren Søndergaard

    Background: Rehabilitation has an increasing focus on intensive resistance training early after joint replacement. This increases the requests for measuring changes in the muscle strength and muscle power over time. Hand-held dynamometer (HHD) is a device used to measure isometric muscle strength...... and Leg Extensor Power Rig (LEPR) is a tool for measuring muscle power. Purpose / Aim of Study: To test the inter-tester reliability of the HHD and the LEPR in Total Hip Arthroplasty (THA) patients. Materials and Methods: Two groups each consisting 20 subjects were included. Mean age was 68.4 years. All...... between the two testers (p=0.62) and the two tests (0.14); ICC=0.91 (95% CI: 0.79;0.96); LOA=±34Watt. Conclusions: The relative reliability was acceptable for both HHD and LEPR. The absolute reliability showed that a change in the muscle strength/power above 18 Newton or 34 Watt can be counted as a real...

  15. Real-time neutron source localization and identification with a hand-held, volumetrically-sensitive, moderating-type neutron spectrometer

    Science.gov (United States)

    Hoshor, C. B.; Myers, E. R.; Oakes, T. M.; Young, S. M.; Currie, J. E.; Scott, P. R.; Miller, W. H.; Bellinger, S. L.; McGregor, D. S.; Caruso, A. N.

    2017-09-01

    Measuring source-dependent properties of free neutrons over a large neutron energy range, with hand-portable instrumentation, continues to push the frontier of neutron detection instrumentation design and analysis techniques. Building on prior work - C.B. Hoshor, et al., A portable and wide energy range semiconductor-based neutron spectrometer, Nucl. Instrum. Methods Phys. Res. A 803 (2015) 68-81 - which focused on demonstrating one-dimensional-based energy-dependent neutron measurement and analysis with a new class of solid-state moderating-type spectrometer, this work introduces two ;core; algorithmic methodologies that expand the analysis of neutron thermalization measurements to three spatial dimensions to determine the location and identity of neutron radiation sources in real time. Two extensions of these core methodologies are then proposed to further improve both the accuracy and reliability of source location and identity determinations with this new class of hand-held instrumentation. In 432 preliminary simulation tests, these method extensions are shown to decrease the average source location error by 64% and provide correct identity determinations in all test cases.

  16. The use of hand-held 35 mm color infrared imagery for estimates of suspended solids - A progress report. [in water pollution monitoring

    Science.gov (United States)

    Miller, W. F.; Whisler, F. D.; Robinette, H. R.; Finnie, D.; Cannon, T.

    1975-01-01

    A cost-effective aerial surveillance technique is proposed for detection and identification of suspended solids which would be operational for both governmental monitoring organizations and private individuals operating catfish farms. Sixteen catfish ponds were flown daily for seven days using two hand-held 35 mm cameras with both Kodachrome X and Ektachrome infrared film. Hue, value, and chroma designations were recorded for each pond on each date by three interpreters, and the accepted color was that recorded by at least two of the interpreters, or if there was a three hue range, the median was accepted. Relations between suspended solids and color designations were analyzed graphically, and chroma was discarded due to an apparent lack of correlation. The data obtained were then analyzed by multiple regression. Significant correlations were revealed between hue and value and total and inorganic suspended solids. If perfected, this technique could be developed to sufficent accuracy for large-scale reconnaissance surveys to monitor the quality of rivers and streams.

  17. The use of hand-held 35 mm color infrared imagery for estimates of suspended solids - A progress report. [in water pollution monitoring

    Science.gov (United States)

    Miller, W. F.; Whisler, F. D.; Robinette, H. R.; Finnie, D.; Cannon, T.

    1975-01-01

    A cost-effective aerial surveillance technique is proposed for detection and identification of suspended solids which would be operational for both governmental monitoring organizations and private individuals operating catfish farms. Sixteen catfish ponds were flown daily for seven days using two hand-held 35 mm cameras with both Kodachrome X and Ektachrome infrared film. Hue, value, and chroma designations were recorded for each pond on each date by three interpreters, and the accepted color was that recorded by at least two of the interpreters, or if there was a three hue range, the median was accepted. Relations between suspended solids and color designations were analyzed graphically, and chroma was discarded due to an apparent lack of correlation. The data obtained were then analyzed by multiple regression. Significant correlations were revealed between hue and value and total and inorganic suspended solids. If perfected, this technique could be developed to sufficent accuracy for large-scale reconnaissance surveys to monitor the quality of rivers and streams.

  18. A combination of hand-held models and computer imaging programs helps students answer oral questions about molecular structure and function: a controlled investigation of student learning.

    Science.gov (United States)

    Harris, Michelle A; Peck, Ronald F; Colton, Shannon; Morris, Jennifer; Chaibub Neto, Elias; Kallio, Julie

    2009-01-01

    We conducted a controlled investigation to examine whether a combination of computer imagery and tactile tools helps introductory cell biology laboratory undergraduate students better learn about protein structure/function relationships as compared with computer imagery alone. In all five laboratory sections, students used the molecular imaging program, Protein Explorer (PE). In the three experimental sections, three-dimensional physical models were made available to the students, in addition to PE. Student learning was assessed via oral and written research summaries and videotaped interviews. Differences between the experimental and control group students were not found in our typical course assessments such as research papers, but rather were revealed during one-on-one interviews with students at the end of the semester. A subset of students in the experimental group produced superior answers to some higher-order interview questions as compared with students in the control group. During the interview, students in both groups preferred to use either the hand-held models alone or in combination with the PE imaging program. Students typically did not use any tools when answering knowledge (lower-level thinking) questions, but when challenged with higher-level thinking questions, students in both the control and experimental groups elected to use the models.

  19. Lactate study using umbilical cord blood: agreement between Lactate Pro hand-held devices with blood gas analyser and evaluation of lactate stability over time.

    Science.gov (United States)

    Su, Tina Y; Reece, Mifanwy; Chua, Seng C

    2013-08-01

    Lactate measurements have become increasingly preferred over pH analysis in the evaluation of fetal acidaemia in labour. In a busy labour ward, often the umbilical cord may be sampled late and as a result yield unreliable lactate values. To investigate the agreement of hand-held device Lactate Pro with a reference method blood gas analyser and evaluate the stability of umbilical cord lactate values over time. Prospective study carried out at elective caesarean section. Sixteen umbilical cords were double clamped immediately after delivery with paired arterial and venous blood samples collected by an independent researcher, at varying time intervals, and processed by two Lactate Pro devices and a reference method blood gas analyser. A significant difference of -0.41 to 0.10 mmol/L was found when different groups of Lactate Pro devices were compared with blood gas analyser at lactate values up to 5.70 mmol/L, with average lactate value of 2.45 mmol/L. Over time, there is progressive rise in lactate samples obtained from the umbilical cord. Lactate Pro devices have a significant difference, but when used in clinical practice on cord blood after delivery, this is unlikely to be meaningful. In intrapartum fetal surveillance, a systematic overestimation might lead to unnecessary intervention. It is possible to retrospectively predict the likely level of lactate at birth in delayed cord samples. © 2013 The Authors ANZJOG © 2013 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

  20. What is the most cost-effective strategy to screen for left ventricular systolic dysfunction: natriuretic peptides, the electrocardiogram, hand-held echocardiography, traditional echocardiography, or their combination?

    Science.gov (United States)

    Galasko, Gavin I W; Barnes, Sophie C; Collinson, Paul; Lahiri, Avijit; Senior, Roxy

    2006-01-01

    To assess the screening characteristics and cost-effectiveness of screening for left ventricular systolic dysfunction (LVSD) in community subjects. A total of 1392 members of the general public and 928 higher risk subjects were randomly selected from seven community practices. Attending subjects underwent an ECG, N-terminal pro-brain natriuretic peptide (NTproBNP) serum levels, and traditional echocardiography (TE). A total of 533 consecutive subjects underwent hand-held echocardiography (HE). The screening characteristics and cost-effectiveness (cost per case of LVSD diagnosed) of eight strategies to predict LVSD (LVSD cost-effective, screening low-risk subjects least cost-effective. TE screening was the least cost-effective strategy. NTproBNP screening gave similar cost savings to ECG screening; HE screening greater cost-savings, and HE screening following NTproBNP or ECG pre-screening the greatest cost-savings, costing approximately 650 Euros per case of LVSD diagnosed in high-risk subjects (63% cost-savings vs.TE). Thus several different modalities allow cost-effective community-based screening for LVSD, especially in high-risk subjects. Such programmes would be cost-effective and miss few cases of LVSD in the community.

  1. Hand-held echocardiography in the setting of pre-operative cardiac evaluation of patients undergoing non-cardiac surgery: results from a randomized pilot study.

    Science.gov (United States)

    Cavallari, Ilaria; Mega, Simona; Goffredo, Costanza; Patti, Giuseppe; Chello, Massimo; Di Sciascio, Germano

    2015-06-01

    Transthoracic echocardiography is not a routine test in the pre-operative cardiac evaluation of patients undergoing non-cardiac surgery but may be considered in those with known heart failure and valvular heart disease or complaining cardiac symptoms. In this setting, hand-held echocardiography (HHE) could find a potential application as an alternative to standard echocardiography in selected patients; however, its utility in this context has not been investigated. The aim of this pilot study was to evaluate the conclusiveness of HHE compared to standard echocardiography in this subset of patients. 100 patients scheduled for non-cardiac surgery were randomized to receive a standard exam with a Philips Ie33 or a bedside evaluation with a pocket-size imaging device (Opti-Go, Philips Medical System). The primary endpoint was the percentage of satisfactory diagnosis at the end of the examination referred as conclusiveness. Secondary endpoints were the mean duration time and the mean waiting time to perform the exams. No significant difference in terms of conclusiveness between HHE and standard echo was found (86 vs 96%; P = 0.08). Mean duration time of the examinations was 6.1 ± 1.2 min with HHE and 13.1 ± 2.6 min with standard echocardiography (P cardiac surgery, since it provided similar information but it was faster and earlier performed compared to standard echocardiography.

  2. Gene Gun Bombardment with DNA-Coated Golden Particles Enhanced the Protective Effect of a DNA Vaccine Based on Thioredoxin Glutathione Reductase of Schistosoma japonicum

    Directory of Open Access Journals (Sweden)

    Yan Cao

    2013-01-01

    Full Text Available Schistosomiasis, caused by infection with Schistosoma species, remains an important parasitic zoonosis. Thioredoxin glutathione reductase of Schistosoma japonicum (SjTGR plays an important role in the development of the parasite and for its survival. Here we present a recombinant plasmid DNA vaccine, pVAX1/SjTGR, to estimate its protection against S. japonicum in BALB/c mice. The DNA vaccine administrated by particle bombardment induced higher protection than by intramuscular injection. All animals vaccinated with pVAX1/SjTGR developed significant specific anti-SjTGR antibodies than control groups. Moreover, animals immunized by gene gun exhibited a splenocyte proliferative response, with an increase in IFN-γ and IL-4. The recombinant plasmid administrated by gene gun achieved a medium protective efficacy of 27.83–38.83% ( of worm reduction and 40.38–44.51% ( of liver egg count reduction. It suggests that different modes of administering a DNA vaccine can influence the protective efficacy induced by the vaccine. Interestingly, from the enzymatic activity results, we found that worms obtained from pVAX1/SjTGR-vaccinated animals expressed lower enzymatic activity than the control group and the antibodies weakened the enzymatic activity of SjTGR in vitro, too. It implies that the high-level antibodies may contribute to the protective effects.

  3. Better self-management and meaningful activities thanks to tablets? Development of a person-centered program to support people with mild dementia and their carers through use of hand-held touch screen devices

    NARCIS (Netherlands)

    Kerkhof, Y.J.; Graff, M.J.L.; Bergsma, A.; Vocht, H.H. de; Droes, R.M.

    2016-01-01

    BACKGROUND: To offer good support to people with dementia and their carers in an aging and Internet society the deployment of hand-held touch screen devices, better known as tablets, and its applications (apps) can be viable and desirable. However, at the moment it is not clear which apps are usable

  4. Guns and Violence. Current Controversies.

    Science.gov (United States)

    Kim, Henny H., Ed.

    This book focuses on gun violence and gun control, presenting both sides of arguments about firearms ownership and gun control. Each of five chapters poses a question about gun control and provides answers for both sides of the question. The following essays are included: (1) "Gun Violence Is Becoming an Epidemic" (Bob Herbert); (2) "Gun Violence…

  5. Electron gun for SSRF

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    A 100 kV triode-electron-gun has been designed and manufactured for the Linac of Shanghai Synchrotron Radiation Facility (SSRF). In this paper the performance of the gun and some key components are described.

  6. Gun Safety (For Kids)

    Science.gov (United States)

    ... hands. Even though guns are featured in many television shows, video games, computer games, and movies, it's ... feels safe. One thing to remember about gun violence at school is that it doesn't happen ...

  7. Evaluation of a hand-held blood gas analyzer for rapid determination of blood gases, electrolytes and metabolites in intensive care setting.

    Science.gov (United States)

    Luukkonen, Antti A M; Lehto, Tiina M; Hedberg, Pirjo S M; Vaskivuo, Tommy E

    2016-04-01

    Intensive care units, operating rooms, emergency departments, and neonatology units need rapid measurements of blood gases, electrolytes, and metabolites. These analyses can be performed in a central laboratory or at the clinic with traditional or compact cassette-type blood gas analyzers such as the epoc blood gas testing system for analyzing whole blood samples at the bedside. In this study, the performance and interchangeability of a hand-held epoc blood gas analyzer was evaluated. The analytical performance of the epoc analyzer was evaluated by determining within-and between-run precisions. The accuracy of the epoc analyzer was assessed by comparing patient results from the device with those obtained with the Siemens Rapidlab 1265 and Rapidpoint RP500 and Siemens Dimension Vista and Sysmex XE-2100 analyzers. The following parameters were measured: pH, pCO2, pO2, Hb (calc), Na+, K+, iCa2+, glucose, and lactate. The CV% of the epoc's between-day imprecision for the various parameters varied from 0.4 to 8.6. The within-run imprecision CV% varied from 0.6 to 5.2. The squared regression coefficient (R2) between the epoc and RL1265 varied from 0.94 to 0.99, with the exception of Na+ and Ca2+ (R2≥0.82). The correlation (R2) of Na+ and K+ between epoc and Dimension Vista was 0.73 and 0.89, respectively. The correlation (R2) of Hb between the epoc and the XE-2100 analyzer was 0.94. With most of the measured blood gas parameters, the epoc analyzer correlated well with reference techniques. The epoc analyzer is suitable for rapid measurement of the blood gases, the electrolytes, and the metabolites in the ICU.

  8. An Approach to Precise Nitrogen Management Using Hand-Held Crop Sensor Measurements and Winter Wheat Yield Mapping in a Mediterranean Environment

    Directory of Open Access Journals (Sweden)

    Lucía Quebrajo

    2015-03-01

    Full Text Available Regardless of the crop production system, nutrients inputs must be controlled at or below a certain economic threshold to achieve an acceptable level of profitability. The use of management zones and variable-rate fertilizer applications is gaining popularity in precision agriculture. Many researchers have evaluated the application of final yield maps and geo-referenced geophysical measurements (e.g., apparent soil electrical conductivity-ECa as a method of establishing relatively homogeneous management zones within the same plot. Yield estimation models based on crop conditions at certain growth stages, soil nutrient statuses, agronomic factors, moisture statuses, and weed/pest pressures are a primary goal in precision agriculture. This study attempted to achieve the following objectives: (1 to investigate the potential for predicting winter wheat yields using vegetation measurements (the Normalized Difference Vegetation Index—NDVI at the beginning of the season, thereby allowing for a yield response to nitrogen (N fertilizer; and (2 evaluate the feasibility of using inexpensive optical sensor measurements in a Mediterranean environment. A field experiment was conducted in two commercial wheat fields near Seville, in southwestern Spain. Yield data were collected at harvest using a yield monitoring system (RDS Ceres II-volumetric meter installed on a combine. Wheat yield and NDVI values of 3498 ± 481 kg ha−1 and 0.67 ± 0.04 nm nm−1 (field 1 and 3221 ± 531 kg ha−1 and 0.68 ± 0.05 nm nm−1 (field 2 were obtained. In both fields, the yield and NDVI exhibited a strong Pearson correlation, with rxy = 0.64 and p < 10−4 in field 1 and rxy = 0.78 and p < 10−4 in field 2. The preliminary results indicate that hand-held crop sensor-based N management can be applied to wheat production in Spain and has the potential to increase agronomic N-use efficiency on a long-term basis.

  9. Reliability of hand-held dynamometry for measurement of lower limb muscle strength in children with Duchenne and Becker muscular dystrophy

    Directory of Open Access Journals (Sweden)

    Wei SHI

    2015-05-01

    Full Text Available Objective To determine the reliability of hand-held dynamometry (HHD for lower limb isometric muscle strength measurement in children with Duchenne and Becker muscular dystrophy (DMD/BMD.  Methods A total of 21 children [20 males and one female; mean age was (7.88 ± 2.87 years, ranging between 3.96-14.09 years; mean age at diagnosis was (5.88 ± 2.88 years, ranging between 1.35-12.89 years; mean height was (120.64 ± 16.30 cm, ranging between 97-153 cm; mean body weight was (24.62 ± 9.05 kg, ranging between 14-50 kg] with DMD (19/21 and BMD (2/21 were involved from Rehabilitation Center of Children's Hospital of Fudan University. The muscle strength of hip, knee and ankle was measured by HHD under standardized test methods. The test-retest results were compared to determine the inter-test reliability, and the results among testers were compared to determine the inter-tester reliability.  Results HHD showed fine inter-tester reliability (ICC = 0.762-0.978 and inter-test reliability (ICC = 0.690-0.938 in measuring lower limb muscle strength of children with DMD/BMD. Results also showed relatively poor reliability in distal muscle groups (foot plantar flexion and dorsiflexion.  Conclusions HHD, showing fine inter-tester and inter-test reliability in measuring the lower limb muscle strength of children with DMD/BMD, can be used in monitoring muscle strength changing and assessing effects of clinical interventions. DOI: 10.3969/j.issn.1672-6731.2015.05.009

  10. Preoperative scintigraphic and intraoperative scintimetric localization of parathyroid adenoma with cationic Tc-99m complexes and a hand-held gamma-probe.

    Science.gov (United States)

    Gallowitsch, H J; Fellinger, J; Kresnik, E; Mikosch, P; Pipam, W; Lind, P

    1997-01-01

    The aim of our study was to evaluate the possibility of intraoperative scintimetric detection of parathyroid adenomas with Tc-99m labelled tracers for its usefulness in dystropic or ectopic adenomas. 12 women with biochemically confirmed hyperparathyroidism were included in our study. After injection of 370 MBq Tc-99m tetrofosmin e.g. sestamibi, preoperative scintigraphy (double phase study and SPECT) was performed and T/NT ratios were evaluated for early, delayed and SPECT images. Surgery was performed using a hand-held gamma-probe after preoperative injection of 555-925 MBq Tc-99m tetrofosmin e.g. sestamibi. Count rates (cts/10 sec) were measured and used for calculating in situ- and ex situ-T/NT ratios. In 9 out of 12 patients, adenoma could be detected on static images. Mean T/NT ratios for Tc-99m tetrofosmin were 1.29 for early and 1.23 for delayed images, respectively 1.39 and 1.23 for early and delayed Tc-99m sestamibi scan. Three cases could only be detected with SPECT reconstruction, 11 of 12 parathyroid adenomas could be confirmed intra-operatively. SPECT with Tc-99m labelled cationic complexes showed advantages in detection, precise localization and contrast over static scintigraphy and should therefore be performed at least in cases with poor or no uptake on static images to avoid failures in detection of deeply sited, dislocated glands or adenomas with low uptake. Intraoperative localization and confirmation of parathyroid adenoma with Tc-99m labelled cationic complexes and a gamma probe is possible an 1 may be useful in case of dys- or ectopic adenoma by influencing surgical approach and operating time.

  11. VALIDATION OF ANSI N42.34 AMERICAN NATIONAL STANDARD PERFORMANCE CRITERIA FOR HAND-HELD INSTRUMENTS FOR THE DETECTION AND IDENTIFICATION OF RADIONUCLIDES

    Energy Technology Data Exchange (ETDEWEB)

    Lorier, T.

    2014-09-03

    SRNL’s validation of ANSI N42.34-D6 for the Domestic Nuclear Detection Office (DNDO) was performed utilizing one hand-held instrument (or RID) – the FLIR identiFINDER 2. Each section of the standard was evaluated via a walk-through or test. NOTE: In Table 1, W = walk-through and T = test, as directed by the Domestic Nuclear Detection Office (DNDO). For a walk-through, the experiment was either setup or reviewed for setup; for a test, the N42.34-D6 procedures were followed with some exceptions and comments noted. SRNL is not fully able to evaluate a RID against Sections 7 (Environmental), 8 (Electromagnetic), and 9 (Mechanical) of N42.34, so those portions of this validation were done in collaboration with Qualtest, Inc. in Orlando, Florida. The walk-throughs and tests of Sections 7, 8, and 9 were performed in Qualtest, Inc. facilities with SRNL providing radiological sources as necessary. Where applicable, assessment results and findings of the walk-throughs and tests were recorded on datasheets and a validation summary is provided. A general comment pertained to test requirements found in another standard and referenced in N42.34-D6. For example, step 1 of the test method in section 8.1.2 states “RF test set up information can be found in IEC 61000-4-3.” It is recommended that any information from other standards necessary for conducting the tests within N42.34 should be posted in N42.34 for simplicity and to prevent the user from having to peruse other documents. Another general comment, as noted by Qualtest, is that a tolerance reference is not listed for each test in sections 7-9. Overall, the N42.34-D6 was proven to be practicable, but areas for improvement and recommendations were identified for consideration prior to final ballot submittal.

  12. A hand-held bus charging and information statistics system%一种手持式公交车收费及信息统计装置

    Institute of Scientific and Technical Information of China (English)

    叶鼎晟; 张凯

    2012-01-01

    A hand-held bus charging and information statistics system is presented, according to passengers ride the journey to collect fees, instead of the traditional sectional charge, it mainly used for counting recent number of Passengers and each station number of getting on and off. By the wireless data transmission module, the information can be sent to platform as reference for waiting passengers. This kind of device makes public travel conveniently because of the compatibility of existing public transit card. The device can store and Summarize passenger information in the bus. Based on the Analysis of traffic flow and passengers flow information, it is also convenient for Bus Company to dispatch and count.%提出了一种手持式公交车收费及信息统计装置,根据乘客所乘坐路程来进行收费,而不是传统的分段式收费,同时可以统计各站上车人数,每站的下车人数以及目前车内人数等;然后通过无线数据传输模块还可以把车上的信息发送到站台上供等车的乘客参考,并且这种装置对于现存的公交卡也能进行读写,为市民绿色出行提供便利。此种装置能将公交车上的客流信息进行储存、汇总,通过对车流、人流的信息进行分析,还能方便公交车公司进行调度和统计。

  13. Whose guns are stolen? The epidemiology of Gun theft victims.

    Science.gov (United States)

    Hemenway, David; Azrael, Deborah; Miller, Matthew

    2017-12-01

    Gun theft is an important source of guns used by criminals. Yet no empirical work has focused on the characteristics of gun owners that distinguish those who have had their guns stolen from those who have not. In this study, we examine the demographics and behavioral characteristics of gun owners who report having had a gun stolen. Data come from a nationally representative probability-based online survey conducted in April 2015, with a linked follow-up survey in November 2015 that asked gun owners about any theft of their guns in the past 5 years. Of 1,604 gun-owning respondents, 2.4% (95% CI 1.6,3.6) reported that one or more guns had been stolen, with a mean number of guns stolen per theft of 1.5 (95% CI 1.0,2.0]. Risk factors for having a gun stolen were owning 6 or more guns, owning guns for protection, carrying a gun in the past month, storing guns unsafely, and living in the South region of the United States. The South accounts for 37% of US households, 43% of gun owners, and two-thirds of all gun thefts. We estimate that there are approximately 250,000 gun theft incidents per year, with about 380,000 guns stolen. We find that certain types of gun owners-who own many guns, who carry guns, and who do not store guns safely-are at higher risk to have their guns stolen. Tracing data show that states in the South are exporters of crime guns used in other states. Our survey results find that the majority of guns stolen in the US come from the South.

  14. Leishmania Mexicana Gp63 cDNA Using Gene Gun Induced Higher Immunity to L. Mexicana Infection Compared to Soluble Leishmania Antigen in BALB/C

    Directory of Open Access Journals (Sweden)

    SA Ali

    2011-09-01

    Full Text Available Background: Leishmaniasis is a worldwide disease prevalent in tropical and sub tropical coun­tries. Many attempts have been made and different strategies have been approached to develop a potent vaccine against Leishmania. DNA immunisation is a method, which is shown to be effec­tive in Leishmania vaccination. Leishmania Soluble Antigen (SLA has also recently been used Leishmania vaccination.Methods: The immunity generated by SLA and L. mexicana gp63 cDNA was compared in groups of 6 mice, which were statistically analysed by student t- test with the P-value of 0.05. SLA was administered by two different methods; intramuscular injection and injection of den­dritic cells (DCs loaded with SLA. L. mexicana gp63 cDNA was administered by the gene gun.Results: Immunisation of BALB/c mice with L. mexicana gp63 resulted in high levels of Th1-type immune response and cytotoxic T lymphocytes (CTL activity, which were accompanied with protection induced by the immunisation against L. mexicana infection. In contrast, administra­tion of SLA, produced a mixed Th1/Th2-type immune responses as well as a high level of CTL activity but did not protect mice from the infection.Conclusion: The results indicate higher protection by DNA immunisation using L. mexicana gp63 cDNA compared to SLA, which is accompanied by a high level of Th1 immune response. However, the CTL activity does not necessarily correlate with the protection induced by the vac­cine. Also, gene gun immunisation is a potential approach in Leishmania vaccination. These find­ings would be helpful in opening new windows in Leishmania vaccine research.

  15. Evaluation of a hand-held far-ultraviolet radiation device for decontamination of Clostridium difficile and other healthcare-associated pathogens

    Directory of Open Access Journals (Sweden)

    Nerandzic Michelle M

    2012-05-01

    Full Text Available Abstract Background Environmental surfaces play an important role in transmission of healthcare-associated pathogens. There is a need for new disinfection methods that are effective against Clostridium difficile spores, but also safe and rapid. The Sterilray™ Disinfection Wand device is a hand-held room decontamination technology that utilizes far-ultraviolet radiation (185-230 nm to kill pathogens. Methods We examined the efficacy of disinfection using the Sterilray device in the laboratory, in rooms of hospitalized patients, and on surfaces outside of patient rooms (i.e. keyboards and portable medical equipment. Cultures for C. difficile, methicillin-resistant Staphylococcus aureus (MRSA, and vancomycin-resistant Enterococcus (VRE were collected from commonly-touched surfaces before and after use of the Sterilray device. Results On inoculated surfaces in the laboratory, application of the Sterilray device at a radiant dose of 100 mJ/cm2 for ~ 5 seconds consistently reduced recovery of C. difficile spores by 4.4 CFU log10, MRSA by 5.4 log10CFU and of VRE by 6.9 log10CFU. A >3 log10 reduction of MRSA and VRE was achieved in ~2 seconds at a lower radiant dose, but killing of C. difficile spores was significantly reduced. On keyboards and portable medical equipment that were inoculated with C. difficile spores, application of the Sterilray device at a radiant dose of 100���mJ/cm2 for ~ 5 seconds reduced contamination by 3.2 log10CFU. However, the presence of organic material reduced the lethal effect of the far-UV radiation. In hospital rooms that were not pre-cleaned, disinfection with the Sterilray device significantly reduced the frequency of positive C. difficile and MRSA cultures (P =0.007. Conclusions The Sterilray™ Disinfection Wand is a novel environmental disinfection technology that rapidly kills C. difficile spores and other healthcare-associated pathogens on surfaces. However, the presence of organic matter

  16. High voltage discharge gene gun used in plant gene engineering%在植物基因工程中应用的高压脉冲放电基因枪

    Institute of Scientific and Technical Information of China (English)

    孙鹞鸿; 秦曾衍

    2001-01-01

    本文介绍了一种用于植物基因工程领域的外源基因导入技术和高压放电基因枪的工作原 理 及关键结构,采用高速摄影法获得了射弹的运动速度。当储能为500J时,测得第一放电电流 峰值为19.3kA,电流上升时间为9μs。生物学试验结果表明,高压放电基因枪能有效地将 外源基因导入植物细胞并得到表达。%This paper describes a technique of introducing foreign gene into pla nt cells and the principles of the high-voltage discharge gene gun and its key s tructures. The velocity of the macroprojectile are measured with high speed phot ography. The main specifications are: when storing energy is 500J,the first max discharge current is 19.3kA and the rise time is 9μs. The biological tests pro v e that the foreign gene can be introduced into plant cells and can be expressed effectively using the high voltage discharge gene gun.

  17. Survey of SRF guns

    Energy Technology Data Exchange (ETDEWEB)

    Belomestnykh, S.

    2011-07-25

    Developing Superconducting RF (SRF) electron guns is an active field with several laboratories working on different gun designs. While the first guns were based on elliptic cavity geometries, Quarter Wave Resonator (QWR) option is gaining popularity. QWRs are especially well suited for producing beams with high charge per bunch. In this talk we will describe recent progress in developing both types of SRF guns. SRF guns made excellent progress in the last two years. Several guns generated beams and one, at HZDR, injected beam into an accelerator. By accomplishing this, HZDR/ELBE gun demonstrated feasibility of the SRF gun concept with a normal-conducting Cs{sub 2}Te cathode. The cathode demonstrated very good performance with the lifetime of {approx}1 year. However, for high average current/high bunch charge operation CsK{sub 2}Sb is preferred as it needs green lasers, unlike UV laser for the Cs{sub 2}Te, which makes it easier to build laser/optics systems. Other high QE photocathodes are being developed for SRF guns, most notably diamond-amplified photocathode. Several QWR guns are under development with one producing beam already. They are very promising for high bunch charge operation. The field is very active and we should expect more good results soon.

  18. Carbon Nanotube Electron Gun

    Science.gov (United States)

    Nguyen, Cattien V. (Inventor); Ribaya, Bryan P. (Inventor)

    2013-01-01

    An electron gun, an electron source for an electron gun, an extractor for an electron gun, and a respective method for producing the electron gun, the electron source and the extractor are disclosed. Embodiments provide an electron source utilizing a carbon nanotube (CNT) bonded to a substrate for increased stability, reliability, and durability. An extractor with an aperture in a conductive material is used to extract electrons from the electron source, where the aperture may substantially align with the CNT of the electron source when the extractor and electron source are mated to form the electron gun. The electron source and extractor may have alignment features for aligning the electron source and the extractor, thereby bringing the aperture and CNT into substantial alignment when assembled. The alignment features may provide and maintain this alignment during operation to improve the field emission characteristics and overall system stability of the electron gun.

  19. Guns at College.

    Science.gov (United States)

    Miller, Matthew; Hemenway, David; Wechsler, Henry

    1999-01-01

    Surveyed undergraduate students nationwide concerning firearm possession. About 3.5% possessed working firearms. Students with guns were more likely to be male, White, or Native American; binge drink; live off-campus; and live with a spouse or significant other. Students with guns were more likely to engage in activities that put themselves and…

  20. The Missing Gun The Missing Gun

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Ma Shan, a criminal poljceman in a remotesmall town in the southwestern Yunnan province,gets drunk at his sister’s wedding and has his three-bullet gun lost, He tries to find it stealthily but endsup in vain. He has tno choice but to report the

  1. 手持式电动工具产品日常检测不合格项目及原因浅析%Unqualified Items and Cause Analysis in Hand-held Electric Tools Routine Test

    Institute of Scientific and Technical Information of China (English)

    高家材; 陈其勇; 郑小龙

    2015-01-01

    基于日常检测尤其是CCC检测和监督抽查以及各类地方抽查的试验,介绍手持式电动工具在测试过程中常见的不合格项目,对不合格项目的产生原因进行简要分析.%Based on the routine test, especially the CCC certification, supervision and various local spot check, introduce the common unqualified items during the process in the hand-held electric tools test, and analyze the cause of the unqualified items briefly.

  2. 简介手持式电动工具爬电距离和电气间隙的测量试验%The Measuring Test of Creepage Distance and Clearance on Hand-held Electric Tools

    Institute of Scientific and Technical Information of China (English)

    戴胜岳

    2014-01-01

    基于对《手持式电动工具的安全第一部分:通用要求》具体章节的理解,通过图例方式对爬电距离和电气间隙测量的试验方法和注意事项做简单介绍。%According to the understanding of Safety of hand-held moter-operated electric tools-part 1:General requirement, to make a simple introduction of creepage distance and clearance test methods and notes by illustration.

  3. 便携式电子测力计在肌力评定中的应用进展%Application Progress of Hand-held Dynamometry in Muscle Strength Assessment

    Institute of Scientific and Technical Information of China (English)

    关润泽; 赵鹏

    2016-01-01

    Objective and accurate evaluation of muscle strength is the core foundation of developing rehabil⁃itation programs, determining the rehabilitation goals, evaluating the treatment effects. Understand the lat⁃est research results of muscle strength testing, comparative study of manual muscle testing and isokinetic testing, hand-held dynamometer testing of a variety of muscle strength method. Results showed that hand-held dynamometer testing compared to traditional manual muscle strength testing more quantitative, and hand-held dynamometer muscle strength measurement value associated with isokinetic testing of strong(r=0.91),and the easy to operate, strong applicability, can effectively discharge effect on muscle strength assess⁃ment of muscular tension. View of hand-held dynamometer with merits of quantitative, accurate and easy to carry, can be widely used in rehabilitation assessment, screening function and monitoring training effect, so as to improve the effectiveness of rehabilitation.%客观准确地肌力评定,是制定康复治疗计划、确定康复目标、评价治疗效果的核心基石。了解现阶段肌力检测的最新研究成果,对比研究徒手肌力检测、等速仪器测试、便携式电子测力计测试等多种肌力检测方法。结果显示,便携式电子测力计相对于传统徒手肌力检测更为量化;同时便携式电子测力计肌力测量值与等速仪器测试相关性较强(r=0.91),且易于操作,应用性较强,能有效排出肌张力对肌力评定的影响。因而鉴于便携式电子测力计有定量、精确和便于携带的优点,能广泛应用于康复评定、功能筛查和训练效果监控过程中。

  4. Gun Dynamics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Gun Dynamics Laboratory is a research multi-task facility, which includes two firing bays, a high bay area and a second floor laboratory space. The high bay area...

  5. Teen Suicide and Guns

    Science.gov (United States)

    ... Issues Listen Text Size Email Print Share Teen Suicide and Guns Page Content Article Body Protect Your ... of a passing problem, not the outcome! Teen Suicide—A Big Problem Suicide is one of the ...

  6. Gun Control Legislation

    Science.gov (United States)

    2010-08-27

    issue for the 111th Congress has been gun trafficking and smuggling across the Southwest border from the United States to Mexico .4 Several...committees have held hearings on gun trafficking and smuggling across the Southwest border from the United States to Mexico . In the Consolidated...emerging technology by which a firearm’s serial number is engraved microscopically with a laser onto the breech face or firing pin of a firearm. When

  7. Electromagnetic configurations of rail guns

    Science.gov (United States)

    Fat'yanov, O. V.; Ostashev, V. E.; Lopyrev, A. N.; Ul'Yanov, A. V.

    1993-06-01

    Some problems associated with the electromagnetic acceleration of macrobodies in a rail gun are examined. An approach to the design of rail gun configurations is proposed, and some basic rail gun schemes are synthesized. The alternative rail gun schemes are compared in terms of electrode potential and stability of the electrode gap with respect to parasitic current shunting. The effect of the ohmic resistance of the electrodes and of the additional magnetization field on the spatial structure of the discharge in the rail gun channel is discussed. A classification of rail gun modifications is presented.

  8. Injury risk of nonpowder guns.

    Science.gov (United States)

    Laraque, Danielle

    2004-11-01

    Nonpowder guns (ball-bearing [BB] guns, pellet guns, air rifles, paintball guns) continue to cause serious injuries to children and adolescents. The muzzle velocity of these guns can range from approximately 150 ft/second to 1200 ft/second (the muzzle velocities of traditional firearm pistols are 750 ft/second to 1450 ft/second). Both low- and high-velocity nonpowder guns are associated with serious injuries, and fatalities can result from high-velocity guns. A persisting problem is the lack of medical recognition of the severity of injuries that can result from these guns, including penetration of the eye, skin, internal organs, and bone. Nationally, in 2000, there were an estimated 21840 (coefficient of variation: 0.0821) injuries related to nonpowder guns, with approximately 4% resulting in hospitalization. Between 1990 and 2000, the US Consumer Product Safety Commission reported 39 nonpowder gun-related deaths, of which 32 were children younger than 15 years. The introduction of high-powered air rifles in the 1970s has been associated with approximately 4 deaths per year. The advent of war games and the use of paintball guns have resulted in a number of reports of injuries, especially to the eye. Injuries associated with nonpowder guns should receive prompt medical management similar to the management of firearm-related injuries, and nonpowder guns should never be characterized as toys.

  9. Automation Study for Longhorn Army Ammunition Plant Hand Held Signal Flight Assembly, Rocket Barrel Assembly, 40 MM Signal, Final Packaging/Pack-Out, and Star Finishing

    Science.gov (United States)

    1990-03-01

    Kenneth Shackelford, Carl Walek, Gene Muehleisen, Jamie Horning, Hugh Hines, Doyle Dorsey, Delbert Barton, John Broderick, E.V. Wilson, Hoss Watkins...refilled a maximum of four cimes an hour. The delay assembly contains energetic material and should be stacked so the material can not rub against the

  10. Electromagnetic Guns versus Conventional Guns - a performance comparison

    NARCIS (Netherlands)

    Reus, N.M. de; Weijden, J. van der

    1993-01-01

    Performance improvement is one of the key issues of Electromagnetic gun systems compared to conventional gun systems. Due to higher muzzle velocities, the gun's fire control computer will be able to predict the target's future position more accurately because prediction time will be smaller. In this

  11. Electromagnetic Guns versus Conventional Guns - a performance comparison

    NARCIS (Netherlands)

    Reus, N.M. de; Weijden, J. van der

    1993-01-01

    Performance improvement is one of the key issues of Electromagnetic gun systems compared to conventional gun systems. Due to higher muzzle velocities, the gun's fire control computer will be able to predict the target's future position more accurately because prediction time will be smaller. In this

  12. Unbalanced field RF electron gun

    Science.gov (United States)

    Hofler, Alicia

    2013-11-12

    A design for an RF electron gun having a gun cavity utilizing an unbalanced electric field arrangement. Essentially, the electric field in the first (partial) cell has higher field strength than the electric field in the second (full) cell of the electron gun. The accompanying method discloses the use of the unbalanced field arrangement in the operation of an RF electron gun in order to accelerate an electron beam.

  13. Middle ground on gun control

    OpenAIRE

    Stewart, Peter A.

    2016-01-01

    Approved for public release; distribution is unlimited Each tragic shooting incident that the American news media covers highlights the problem of gun violence in the United States. However, the focus of this reporting is rarely on the largest component of total gun deaths: suicides. Suicides make up two-thirds of all gun deaths. Limiting access to firearms for individuals with suicidal tendencies could cause a significant reduction in the total number of casualties included in gun violenc...

  14. Micro-fluidic (Lab-on the- Chip) PCR Array Cartridge for Biological Screening in a Hand Held Device: FInal Report for CRADA no 264. PNNL-T2-258-RU with CombiMatrix Corp

    Energy Technology Data Exchange (ETDEWEB)

    Rainina, Evguenia I.

    2010-10-31

    The worldwide emergence of both new and old diseases resulting from human expansion and also human and materials mobility has and will continue to place stress on both medical and clinical diagnostics. The classical approach to bioagents detection involves the use of differential metabolic assays to determine species type in the case of most bacteria, or the use of cell culture and electron microscopy to diagnose viruses and some bacteria that are intracellular parasites. The long-term goal in bioagent detection is to develop a hand-held instrument featuring disposable cartridges which contain all the necessary reagents, reaction chambers, waste chambers, and micro-fluidics to extract, concentrate, amplify, and analyze nucleic acids. This GIPP project began development of a sensory platform using nucleic-acid based probes. Although research was not completed, initial findings indicated that an advanced sensing device could theoretically be built on a DNA/RNA-based technology platform.

  15. 手持式电动工具防止触及带电零件的保护试验%Protection against Access to Live Parts Test of Hand-held Electric Tools

    Institute of Scientific and Technical Information of China (English)

    王韦华

    2014-01-01

    According to the understanding of the standard of protection against access to live parts test of hand-held electric tools, brief introduce the test methods and results determination by legends, including the test equipments, test methods, results determination and precautions.%根据对手持式电动工具防止触及带电零件试验的标准理解,通过图例对该试验方法和结果判定作简单介绍,包括试验设备、试验方法、结果判定以及注意事项等方面。

  16. 手持式电动工具用轴承性能浅析%Brief Performance Analysis on the Bearings Applied to Hand-held Motor-operated Electric Tools

    Institute of Scientific and Technical Information of China (English)

    张永恩; 方承志; 宋贵州; 李兴林

    2014-01-01

    Deep groove ball bearings, represented in the tool assembly without considering other factors, combined with the relevant sections of the power tool safety standards, the content mainly discusses several performance requirements of the bearings applied to hand-held motor-operated electric tools and their relationship and effects with safety standard. This content can also be referenced while make technical design and quality appraisal.%以深沟球轴承为代表,在不考虑工具装配等因素的前提下,结合电动工具安全标准的相关章节,讨论并分析手持式电动工具用滚动轴承的主要性能和要求,可供设计选用和质量评价时参考。

  17. Glue Guns: Aiming for Safety

    Science.gov (United States)

    Roy, Ken

    2010-01-01

    While glue guns are very useful, there are safety issues. Regardless of the temperature setting, glue guns can burn skin. The teacher should demonstrate and supervise the use of glue guns and have a plan should a student get burned. There should be an initial first aid protocol in place, followed by a visit to the school nurse. An accident report…

  18. The reliability and validity of measurements of human dental casts made by an intra-oral 3D scanner, with conventional hand-held digital callipers as the comparison measure.

    Science.gov (United States)

    Rajshekar, Mithun; Julian, Roberta; Williams, Anne-Marie; Tennant, Marc; Forrest, Alex; Walsh, Laurence J; Wilson, Gary; Blizzard, Leigh

    2017-09-01

    Intra-oral 3D scanning of dentitions has the potential to provide a fast, accurate and non-invasive method of recording dental information. The aim of this study was to assess the reliability of measurements of human dental casts made using a portable intra-oral 3D scanner appropriate for field use. Two examiners each measured 84 tooth and 26 arch features of 50 sets of upper and lower human dental casts using digital hand-held callipers, and secondly using the measuring tool provided with the Zfx IntraScan intraoral 3D scanner applied to the virtual dental casts. The measurements were repeated at least one week later. Reliability and validity were quantified concurrently by calculation of intra-class correlation coefficients (ICC) and standard errors of measurement (SEM). The measurements of the 110 landmark features of human dental casts made using the intra-oral 3D scanner were virtually indistinguishable from measurements of the same features made using conventional hand-held callipers. The difference of means as a percentage of the average of the measurements by each method ranged between 0.030% and 1.134%. The intermethod SEMs ranged between 0.037% and 0.535%, and the inter-method ICCs ranged between 0.904 and 0.999, for both the upper and the lower arches. The inter-rater SEMs were one-half and the intra-method/rater SEMs were one-third of the inter-method values. This study demonstrates that the Zfx IntraScan intra-oral 3D scanner with its virtual on-screen measuring tool is a reliable and valid method for measuring the key features of dental casts. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Serbian society and gun culture

    Directory of Open Access Journals (Sweden)

    Cvetković Vladimir

    2006-01-01

    Full Text Available This paper questions whether one characteristic of Serbian society is a gun culture. The first part of the paper deals with some theoretical concerns and closer explanation of what is understood by the term gun culture. Few different approaches to the issue are analyzed. The concept used has three main components of the gun culture: system of positive beliefs; social symbols embodied by the gun; agent "bearers" of gun culture. The second part of the paper presents results from Small Arms and Light Weapons survey conducted in 2004 in Serbia. The results were analyzed within the theoretical framework proposed in the first part of the paper.

  20. E-Gun Technology

    Science.gov (United States)

    1981-07-01

    AD E-GUN TECHNOLOGY N FINAL TECHNICAL REPORT J. E. Eninger , H. W. Friedman and K. E. Williams AVCO EVERETT RESEARCH LABORATORY, INC. Contract No...Report J.E. Eninger , H.W. Friedman and K.E. Williams AVCO EVERETT RESEARCH LABORATORY, INC. A Subsidiary of Avco Corporation 2385 Revere Beach Parkway

  1. The Rail Gun.

    Science.gov (United States)

    Stewart, Gay B.

    1996-01-01

    Presents a rail gun demonstration that addresses a broad group of educational goals in introductory electricity and magnetism. Uses a battery-powered circuit consisting of a movable conductor placed across two conducting rails in a magnetic field to review mechanics, foster approximate reasoning and lateral class discussion, and demonstrate the…

  2. 120 Hz Gun Review

    Energy Technology Data Exchange (ETDEWEB)

    Colby, E.

    2005-01-31

    The review was held at SLAC on September 11 and 12, 2001. Presentations concerning the thermal analysis, mechanical design, integration with the laser and accelerator, general beam dynamics considerations, a load lock mechanism, and symmetric power feed options comprised the review. Slides from these presentations are available elsewhere. The review committee was charged with evaluating the 120 Hz gun design including proposed load lock and power feed options and recommending improvements. Broader evaluation of the injector as a whole (including focusing and diagnostic systems that do no impact the envelope of the gun itself) is expected to be covered in a future review and will not be commented on here. In general, the long operational experience with four generations of s-band RF guns at numerous labs worldwide has led to considerable experience in design, fabrication, and operation aspects, and provides an excellent base on which to design the higher duty factor LCLS injector. While open questions remain on obtaining the design performance from these injectors, the microwave design of the gun has reached a state of relative maturity.

  3. Giving Up the Gun.

    Science.gov (United States)

    LaRue, Robert D.

    1989-01-01

    Provides a model lesson from the book "Science/Technology/Society: Model Lessons for Secondary Social Studies Classes." Outlines Japan's campaign in the seventeenth and eighteenth centuries to rid itself of guns and return to swords. Provides background information and student handouts. (RW)

  4. Gun Attitudes and Fear of Crime.

    Science.gov (United States)

    Heath, Linda; Weeks, Kyle; Murphy, Marie Mackay

    1997-01-01

    Using three studies, examined the relationship between attitudes toward guns and fear of crime. Findings indicate a connection between fear of crime and attitudes toward guns: people higher in fear of crime favored gun control. Results also established a relationship between stereotypical beliefs about gun victims and support for gun control. (RJM)

  5. Friction in rail guns

    Science.gov (United States)

    Kay, P. K.

    1984-01-01

    The influence of friction is included in the present equations describing the performance of an inductively driven rail gun. These equations, which have their basis in an empirical formulation, are applied to results from two different experiments. Only an approximate physical description of the problem is attempted, in view of the complexity of details in the interaction among forces of this magnitude over time periods of the order of milisecs.

  6. Keeping Naval Guns Ready

    Science.gov (United States)

    2016-03-01

    April 2016 22 Between 1990 and 2014, the world economy doubled, rising from $35 trillion to $75 trillion, lifting billions of people out of poverty ...surface combatants have been directed to conduct daily exercises, firing .50 caliber to 5-inch guns. Because of their extensive use in the severe...Mark 15 Close-In Weapon System, on all Navy surface combatant ships 23 Defense AT&L: March-April 2016 • 25 mm, Mark 38, on Navy aircraft

  7. 手持式压力测痛仪的信度及效度检验%Reliability and validity of the hand-held pressure algometer as a measuring instrument of pressure pain threshold

    Institute of Scientific and Technical Information of China (English)

    陈祢; 郭铁成; 许惊飞; 韦春霞

    2009-01-01

    目的 均较高(ICC>0.95),重测信度优于施测者间信度;根据同一施测者3次重复测量结果的均值所计算的施测者间信度高于单次测量的施测者间信度;肌筋膜痛患者激痛点与正常对照点的压痛阈差异具有统计学意义,激痛点压痛阈值与VAS评分呈显著的负相关.结论 手持式压力测痛仪测量正常健康人压痛阈时具有较高信度,其可作为量化评价激痛点疼痛敏感性的有效工具.%Objective To evaluate the test-retest and inter-rater reliability of the hand-held pressure algometer as a measuring instrument of pressure pain threshold(PPT).Method A total of 37 healthy subjects were recruited for reliability test.Three raters measured the PPT at 12 body sites of the subjects.Each rater conducted three trials on each site.In the validity test,10 patients with active trigger points in the upper trapezius were recruited and measured by one rater using the pressure algometer for PPT,the visual analogue scale(VAS)was also used to evaluate the pain intensity induced by the trigger point.The intraclass correlation coefficient and Spearman correlation coefficient were calculated to reflect the reliability and validity.Results The test-retest and inter-rater reliabilities were both high(ICC>0.95),with the measurements by one rater were more reliable than measurements by multiple raters.The inter-rater reliability of PPT measurement obtained by using the mean value of 3 trials was higher than any of the 3 trials alone.The PPT values of the trigger points were higher than those of the normal points,and there was a significantly negative correlation between the PPT values of the trigger points and the VAS scores.Conclusion The intra-and inter-rater PPT measurements in healthy subjects obtained with the hand-held pressure algometer were highly reliable.The algometer was valid for quantifying myofascial trigger point sensitivity.

  8. Mole gun injury.

    Science.gov (United States)

    Pistré, V; Rezzouk, J

    2013-09-01

    A mole gun is a weapon, which is used to trap and kill moles. This report provides an overview of the state of knowledge of mole gun injuries, comparable to blast injuries caused by fireworks, explosive or gunshot. Over a 2-year period, the authors reported their experience with ten hand injuries caused by mole gun. Radial side of the hand was often concerned, particularly the thumb. The authors explain their choices in the management of such lesions. Surgery was performed primarily and a large debridement currently seemed to offer the best outcome for the patient. Blast, crush, burns and lacerations may explain the higher rate of amputation to the digits. A long period of physiotherapy, specifically of the hand, was needed before the patient could return to work. This ballistic hand trauma encountered by surgeons requires knowledge and understanding of these injuries. It should be in accordance with firearms law because of severe injuries encountered and possible lethal wounds. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  9. Improved DC Gun Insulator

    Energy Technology Data Exchange (ETDEWEB)

    M.L. Neubauer, K.B. Beard, R. Sah, C. Hernandez-Garcia, G. Neil

    2009-05-01

    Many user facilities such as synchrotron light sources and free electron lasers require accelerating structures that support electric fields of 10-100 MV/m, especially at the start of the accelerator chain where ceramic insulators are used for very high gradient DC guns. These insulators are difficult to manufacture, require long commissioning times, and have poor reliability, in part because energetic electrons bury themselves in the ceramic, creating a buildup of charge and causing eventual puncture. A novel ceramic manufacturing process is proposed. It will incorporate bulk resistivity in the region where it is needed to bleed off accumulated charge caused by highly energetic electrons. This process will be optimized to provide an appropriate gradient in bulk resistivity from the vacuum side to the air side of the HV standoff ceramic cylinder. A computer model will be used to determine the optimum cylinder dimensions and required resistivity gradient for an example RF gun application. A ceramic material example with resistivity gradient appropriate for use as a DC gun insulator will be fabricated by glazing using doping compounds and tested.

  10. Air guns: toys or weapons?

    Science.gov (United States)

    Aslan, Sahin; Uzkeser, Mustafa; Katirci, Yavuz; Cakir, Zeynep; Bilir, Ozlem; Bilge, Fatih; Cakir, Murtaza

    2006-09-01

    Air guns and blank guns may appear relatively harmless at first glance, but they are, in fact, potentially destructive, even lethal, weapons. Approximately 2 to 2.5 million nonpowder firearms are sold annually, and again approximately 12.9 per 100,000 population are treated for such injuries in hospital emergency departments each year in the United States. Unfortunately, these guns are considered to be a toy for children. Therefore, incidents of air gun injuries are gradually increasing. Although such injuries may initially be considered trivial, it may signify severe internal tissue pathologies. These apparently trivial injuries may have catastrophic consequences if unnoticed. In this study, we report 4 cases with head injury due to a shot by these guns. The cases indicate that these people had used the guns belonging to their parents for the purpose of suicide. The cases also show that these machines are not innocent.

  11. CAPE TOWN'S TIME-GUNS

    Directory of Open Access Journals (Sweden)

    W.M. Bisset

    2012-02-01

    Full Text Available Although a great many articles have been written on the subject of Cape Town's noon gun (the. official terminology is 'time-gun' most of the writers have not had access to the Lion Battery Fort Record Book and the existance of more than one Cape Town time-gun has only recently been recorded. By 1807 a noon gun was fired regularly from the Imhoff Battery on the seaward side of the Castle.1 On 4 August 1902 the noon gun was fired from Lion Battery on Signal Hill for the first time.2 The battery was built because of fears of war with Russia and had been armed with two 9- inch Rifled Muzzle Loading guns by 1891. Lion Battery was remodelled in 1911.

  12. Development of a Hand Held Thromboelastograph

    Science.gov (United States)

    2014-01-01

    Subtask 1d: Robustness of device architecture: 1 meter drop test Subtasks 1a – 1d are complete. The voice coil actuator (VCA) motors will generate a...into the 75 µ gap between the two glass plates. A shear rate of 1000/s was chosen based on the data. A one- meter drop test was conducted in-house...interaction • Technical improvements to handheld device and disposable cartridge were identified based on initial testing, and implementation began

  13. Development of a Hand Held Thromboelastograph

    Science.gov (United States)

    2015-01-01

    98/79/EC In Vitro Diagnostic Medical Devices ISO 9001 :2008 Quality management systems- Requirements ISO 13485:2012 Medical Device Quality Management...in compliance with ISO 13485 and the FDA Quality System Regulation 21CFR Part 820. In addition, the following applicable standards and guidance...Statistical aspects ISO 14971:2012 Application of Risk Management to Medical Devices ISO 15223-1:2012 Medical devices. Symbols to be used with medical

  14. Hand-held operational demining system

    OpenAIRE

    2005-01-01

    The article presents selected results from theoretical and experimental investigations concerned with radar backscattering from typical antipersonnel land mines (APL) in the frequency range of about 200 MHz to 8 GHz in order to improve the conventional metal detector demining technology presently still widely in use.

  15. Hand-held microwave search detector

    Science.gov (United States)

    Daniels, David J.; Philippakis, Mike

    2005-05-01

    This paper describes the further development of a patented, novel, low cost, microwave search detector using noise radar technology operating in the 27-40GHz range of frequencies, initially reported in SPIE 2004. Initial experiments have shown that plastic explosives, ceramics and plastic material hidden on the body can be detected with the system. This paper considers the basic physics of the technique and reports on the development of a initial prototype system for hand search of suspects and addresses the work carried out on optimisation of PD and FAR. The radar uses a novel lens system and the design and modelling of this for optimum depth of field of focus will be reported.

  16. Wisconsin SRF Electron Gun Commissioning

    Energy Technology Data Exchange (ETDEWEB)

    Bisognano, Joseph J. [University of Wisconsin-Madison; Bissen, M. [University of Wisconsin-Madison; Bosch, R. [University of Wisconsin-Madison; Efremov, M. [University of Wisconsin-Madison; Eisert, D. [University of Wisconsin-Madison; Fisher, M. [University of Wisconsin-Madison; Green, M. [University of Wisconsin-Madison; Jacobs, K. [University of Wisconsin-Madison; Keil, R. [University of Wisconsin-Madison; Kleman, K. [University of Wisconsin-Madison; Rogers, G. [University of Wisconsin-Madison; Severson, M. [University of Wisconsin-Madison; Yavuz, D. D. [University of Wisconsin-Madison; Legg, Robert A. [JLAB; Bachimanchi, Ramakrishna [JLAB; Hovater, J. Curtis [JLAB; Plawski, Tomasz [JLAB; Powers, Thomas J. [JLAB

    2013-12-01

    The University of Wisconsin has completed fabrication and commissioning of a low frequency (199.6 MHz) superconducting electron gun based on a quarter wave resonator (QWR) cavity. Its concept was optimized to be the source for a CW free electron laser facility. The gun design includes active tuning and a high temperature superconducting solenoid. We will report on the status of the Wisconsin SRF electron gun program, including commissioning experience and first beam measurements.

  17. 手持式电动工具维修风险和零件选配技术研究%Research on Repair Risk and Component Matching Technology of Hand-held Electric Tools

    Institute of Scientific and Technical Information of China (English)

    金勇; 傅俊雅

    2014-01-01

    模拟手持式电动工具维修情况,对手持式电动工具的电源线、开关、碳刷以及抑制电容电感等关键零部件进行更换试验,按照相关的国家标准要求分别对替换后的安全、电磁兼容等项目进行测试和数据比对。分析常见的手持式电动工具关键零部件被替换为非原厂零件的特征。%We simulate key parts changing in maintenance and repair when using non original parts, mainly power supply cord, switch, brush and capacitor and inductance, doing lots of tests and data comparison according to the national standards of safety and electromagnetic compatible. We f ind out common characteristics that key parts are replaced by non-original parts in hand-held electric tools.

  18. Weight of RCL Guns in Comparison to Conventional Guns

    Directory of Open Access Journals (Sweden)

    J. P. Sirpal

    1956-07-01

    Full Text Available A study has been made of the weight of ordnance and equipment for a given performance. The comparative weights of the RCL and the orthodox equipments have been studied and it has been found that for the same muzzle energy the weight of RCL gun is 1/4th that of orthodox gun.

  19. Gun Concerns Personal for Duncan

    Science.gov (United States)

    McNeil, Michele

    2013-01-01

    As U.S. Secretary of Education Arne Duncan works with other Obama administration officials on policy responses to the shootings at a Connecticut elementary school, he brings a personal and professional history that has acquainted him with the impact of gun violence. As schools chief in Chicago from 2001 to 2008, he was affected by the gun deaths…

  20. Gun Concerns Personal for Duncan

    Science.gov (United States)

    McNeil, Michele

    2013-01-01

    As U.S. Secretary of Education Arne Duncan works with other Obama administration officials on policy responses to the shootings at a Connecticut elementary school, he brings a personal and professional history that has acquainted him with the impact of gun violence. As schools chief in Chicago from 2001 to 2008, he was affected by the gun deaths…

  1. LCLS Gun Solenoid Design Considerations

    Energy Technology Data Exchange (ETDEWEB)

    Schmerge, John

    2010-12-10

    The LCLS photocathode rf gun requires a solenoid immediately downstream for proper emittance compensation. Such a gun and solenoid have been operational at the SSRL Gun Test Facility (GTF) for over eight years. Based on magnetic measurements and operational experience with the GTF gun solenoid multiple modifications are suggested for the LCLS gun solenoid. The modifications include adding dipole and quadrupole correctors inside the solenoid, increasing the bore to accommodate the correctors, decreasing the mirror plate thickness to allow the solenoid to move closer to the cathode, cutouts in the mirror plate to allow greater optical clearance with grazing incidence cathode illumination, utilizing pancake coil mirror images to compensate the first and second integrals of the transverse fields and incorporating a bipolar power supply to allow for proper magnet standardization and quick polarity changes. This paper describes all these modifications plus the magnetic measurements and operational experience leading to the suggested modifications.

  2. Preventing gun injuries in children.

    Science.gov (United States)

    Crossen, Eric J; Lewis, Brenna; Hoffman, Benjamin D

    2015-02-01

    Firearms are involved in the injury and death of a large number of children each year from both intentional and unintentional causes. Gun ownership in homes with children is common, and pediatricians should incorporate evidence-based means to discuss firearms and protect children from gun-related injuries and violence. Safe storage of guns, including unloaded guns locked and stored separately from ammunition, can decrease risks to children, and effective tools are available that pediatricians can use in clinical settings to help decrease children's access to firearms. Furthermore, several community-based interventions led by pediatricians have effectively reduced firearm-related injury risks to children. Educational programs that focus on children's behavior around guns have not proven effective. © American Academy of Pediatrics, 2015. All rights reserved.

  3. Guns and sleep

    Directory of Open Access Journals (Sweden)

    Quan SF

    2015-08-01

    Full Text Available No abstract available. Article truncated at 150 words. Gun deaths are a problem in America. Irrespective of one’s position on gun control, the statistics do not lie. According to the Centers for Disease Control and Prevention (CDC, there were 11,208 deaths caused by firearms in 2013 (1. The recent high profile cases in Cincinnati, OH, Lafayette, LA and Memphis, TN further highlight the issue. Obviously, each case of death by a firearm had its own set of underlying factors that contributed to the final fatal outcome, but one wonders whether sleep deprivation can be implicated in some of them. Sleep duration in adults over the past approximately 30 years has been declining in the United States (2. A variety of reasons can be cited as underlying causes such as greater use of artificial lighting, an expanding 24 hour non-stop society, promotion of a work ethic that values “burning the midnight oil”, and use of electronic devices before bedtime ...

  4. Gun Shows and Gun Violence: Fatally Flawed Study Yields Misleading Results

    Science.gov (United States)

    Hemenway, David; Webster, Daniel; Pierce, Glenn; Braga, Anthony A.

    2010-01-01

    A widely publicized but unpublished study of the relationship between gun shows and gun violence is being cited in debates about the regulation of gun shows and gun commerce. We believe the study is fatally flawed. A working paper entitled “The Effect of Gun Shows on Gun-Related Deaths: Evidence from California and Texas” outlined this study, which found no association between gun shows and gun-related deaths. We believe the study reflects a limited understanding of gun shows and gun markets and is not statistically powered to detect even an implausibly large effect of gun shows on gun violence. In addition, the research contains serious ascertainment and classification errors, produces results that are sensitive to minor specification changes in key variables and in some cases have no face validity, and is contradicted by 1 of its own authors’ prior research. The study should not be used as evidence in formulating gun policy. PMID:20724672

  5. Gun shows and gun violence: fatally flawed study yields misleading results.

    Science.gov (United States)

    Wintemute, Garen J; Hemenway, David; Webster, Daniel; Pierce, Glenn; Braga, Anthony A

    2010-10-01

    A widely publicized but unpublished study of the relationship between gun shows and gun violence is being cited in debates about the regulation of gun shows and gun commerce. We believe the study is fatally flawed. A working paper entitled "The Effect of Gun Shows on Gun-Related Deaths: Evidence from California and Texas" outlined this study, which found no association between gun shows and gun-related deaths. We believe the study reflects a limited understanding of gun shows and gun markets and is not statistically powered to detect even an implausibly large effect of gun shows on gun violence. In addition, the research contains serious ascertainment and classification errors, produces results that are sensitive to minor specification changes in key variables and in some cases have no face validity, and is contradicted by 1 of its own authors' prior research. The study should not be used as evidence in formulating gun policy.

  6. Guns as a Symbol of American Individualism

    Institute of Scientific and Technical Information of China (English)

    许丹

    2011-01-01

    Due to continuous gun violence, Americans' crazy love for guns has always been attacked home and abroad. Americans' passion for guns derives from individualism through the development of American history. They consider guns as a means to guarantee independence and freedom, and therefore as a symbol of American individualism.

  7. Calculating effective gun control policies

    CERN Document Server

    Wodarz, Dominik

    2013-01-01

    Following recent shootings in the USA, a debate has erupted, one side favoring stricter gun control, the other promoting protection through more weapons. We provide a scientific foundation to inform this debate, based on population dynamic models that quantify the dependence of firearm-related death rates of people on gun policies. We assume a shooter attacking a single individual or a crowd. Two strategies can minimize deaths in the model, depending on parameters: either a ban of private firearms possession, or a policy allowing the general population to carry guns. In particular, the outcome depends on the fraction of offenders that illegally possess a gun, on the degree of protection provided by gun ownership, and on the fraction of the population who take up their right to own a gun and carry it with them when attacked, parameters that can be estimated from statistical data. With the measured parameters, the model suggests that if the gun law is enforced at a level similar to that in the United Kingdom, g...

  8. Gun barrel erosion - Comparison of conventional and LOVA gun propellants

    NARCIS (Netherlands)

    Hordijk, A.C.; Leurs, O.

    2006-01-01

    The research department Energetic Materials within TNO Defence, Security and Safety is involved in the development and (safety and insensitive munitions) testing of conventional (nitro cellulose based) and thermoplastic elastomer (TPE) based gun propellants. Recently our testing capabilities have

  9. Gun barrel erosion - Comparison of conventional and LOVA gun propellants

    NARCIS (Netherlands)

    Hordijk, A.C.; Leurs, O.

    2006-01-01

    The research department Energetic Materials within TNO Defence, Security and Safety is involved in the development and (safety and insensitive munitions) testing of conventional (nitro cellulose based) and thermoplastic elastomer (TPE) based gun propellants. Recently our testing capabilities have be

  10. Temporal association between federal gun laws and the diversion of guns to criminals in Milwaukee.

    Science.gov (United States)

    Webster, Daniel W; Vernick, Jon S; Bulzacchelli, Maria T; Vittes, Katherine A

    2012-02-01

    The practices of licensed gun dealers can threaten the safety of urban residents by facilitating the diversion of guns to criminals. In 2003, changes to federal law shielded gun dealers from the release of gun trace data and provided other protections to gun dealers. The 14-month period during which the dealer did not sell junk guns was associated with a 68% reduction in the diversion of guns to criminals within a year of sale by the dealer and a 43% increase in guns diverted to criminals following sales by other dealers. The laws were associated with a 203% increase in the number of guns diverted to criminals within a year of sale by the gun store, which was the focus of this study. Policies which affect gun dealer accountability appeared to influence the diversion of guns to criminals.

  11. Reverse Ballistic Air Gun Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This custom-designed facility houses a suite of three air guns capable of generating accelerations up to 100,000 Gs and velocities up to 2,000 ft/s. In addition to a...

  12. Reverse Ballistic Air Gun Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This custom-designed facility houses a suite of three air guns capable of generating accelerations up to 100,000 Gs and velocities up to 2,000 ft/s. In addition to...

  13. State Gun Law Environment and Youth Gun Carrying in the United States.

    Science.gov (United States)

    Xuan, Ziming; Hemenway, David

    2015-11-01

    Gun violence and injuries pose a substantial threat to children and youth in the United States. Existing evidence points to the need for interventions and policies for keeping guns out of the hands of children and youth. (1) To examine the association between state gun law environment and youth gun carrying in the United States, and (2) to determine whether adult gun ownership mediates this association. This was a repeated cross-sectional observational study design with 3 years of data on youth gun carrying from US states. The Youth Risk Behavior Survey comprises data of representative samples of students in grades 9 to 12 from biennial years of 2007, 2009, and 2011. We hypothesized that states with more restrictive gun laws have lower rates of youth gun carrying, and this association is mediated by adult gun ownership. State gun law environment as measured by state gun law score. Youth gun carrying was defined as having carried a gun on at least 1 day during the 30 days before the survey. In the fully adjusted model, a 10-point increase in the state gun law score, which represented a more restrictive gun law environment, was associated with a 9% decrease in the odds of youth gun carrying (adjusted odds ratio [AOR], 0.91 [95% CI, 0.86-0.96]). Adult gun ownership mediated the association between state gun law score and youth gun carrying (AOR, 0.94 [ 95% CI, 0.86-1.01], with 29% attenuation of the regression coefficient from -0.09 to -0.07 based on bootstrap resampling). More restrictive overall gun control policies are associated with a reduced likelihood of youth gun carrying. These findings are relevant to gun policy debates about the critical importance of strengthening overall gun law environment to prevent youth gun carrying.

  14. Design of Hand-held Picking Device for Brasenia Schreber Aquatic Plant%水生莼菜植物手动控制采摘器的设计

    Institute of Scientific and Technical Information of China (English)

    夏春风; 马燕平; 沈长生; 张宇

    2014-01-01

    针对水生莼菜植物手工采摘辛苦、效率低下等问题,设计了一种手动控制的莼菜采摘器,分析了其工作原理,给出莼菜切割力计算公式。该采摘器由人手驱动,通过向后逐渐收紧手柄,使与手柄相连的钢丝后移,后移的钢丝再带动直槽形钢片、刀片支架等运动,使主、副刀片闭合,完成莼菜切割运动。然后,操作者将采摘装置移出水面,将切割好的莼菜移到收集装置的网兜上方,松开手柄,主、副刀片自动松开,使莼菜自然落入网兜中。实验表明,该采摘器能达到设计要求,且可靠性高、使用方便、控制灵活,对莼菜和水体均不造成污染。%Am at to solve the problem that brasenia schreberi aquatic plant picked hard and low efficiency by hand , a hand-held picking device for brasenia schreber was designed .Its working principle was introduced , and the calculation formula of brasenia schreberi cutting force was presented .The picking device was driven by hand and by tightening the handle backwards , so that the steel wire connected to the handle moved backward ,the back steel wire drove the piece of straight-shaped steel and the blade holder , closed the main and auxiliary blade and completed cutting brasenia schreberi .Then , the picking device was moved out of the water by the operator , the cut brasenia schreberi was moved to the above net of collecting device ,fell into the net naturally by loosening the handle and releasing the main and auxiliary blade automatically .The picking device of design and manufacture can meet the design requirements through practice test and does not pollute the water and brasenia schreberi .The picking device has the advantages of high reliability , conven-ient to use ,flexible control .

  15. The case for moderate gun control.

    Science.gov (United States)

    DeGrazia, David

    2014-03-01

    In addressing the shape of appropriate gun policy, this essay assumes for the sake of discussion that there is a legal and moral right to private gun ownership. My thesis is that, against the background of this right, the most defensible policy approach in the United States would feature moderate gun control. The first section summarizes the American gun control status quo and characterizes what I call "moderate gun control." The next section states and rebuts six leading arguments against this general approach to gun policy. The section that follows presents a positive case for moderate gun control that emphasizes safety in the home and society as well as rights whose enforcement entails some limits or qualifications on the right to bear arms. A final section shows how the recommended gun regulations address legitimate purposes, rather than imposing arbitrary restrictions on gun rights, and offers concluding reflections.

  16. Large Bore Powder Gun Qualification (U)

    Energy Technology Data Exchange (ETDEWEB)

    Rabern, Donald A. [Los Alamos National Laboratory; Valdiviez, Robert [Los Alamos National Laboratory

    2012-04-02

    A Large Bore Powder Gun (LBPG) is being designed to enable experimentalists to characterize material behavior outside the capabilities of the NNSS JASPER and LANL TA-55 PF-4 guns. The combination of these three guns will create a capability to conduct impact experiments over a wide range of pressures and shock profiles. The Large Bore Powder Gun will be fielded at the Nevada National Security Site (NNSS) U1a Complex. The Complex is nearly 1000 ft below ground with dedicated drifts for testing, instrumentation, and post-shot entombment. To ensure the reliability, safety, and performance of the LBPG, a qualification plan has been established and documented here. Requirements for the LBPG have been established and documented in WE-14-TR-0065 U A, Large Bore Powder Gun Customer Requirements. The document includes the requirements for the physics experiments, the gun and confinement systems, and operations at NNSS. A detailed description of the requirements is established in that document and is referred to and quoted throughout this document. Two Gun and Confinement Systems will be fielded. The Prototype Gun will be used primarily to characterize the gun and confinement performance and be the primary platform for qualification actions. This gun will also be used to investigate and qualify target and diagnostic modifications through the life of the program (U1a.104 Drift). An identical gun, the Physics Gun, will be fielded for confirmatory and Pu experiments (U1a.102D Drift). Both guns will be qualified for operation. The Gun and Confinement System design will be qualified through analysis, inspection, and testing using the Prototype Gun for the majority of process. The Physics Gun will be qualified through inspection and a limited number of qualification tests to ensure performance and behavior equivalent to the Prototype gun. Figure 1.1 shows the partial configuration of U1a and the locations of the Prototype and Physics Gun/Confinement Systems.

  17. Galois Got his Gun

    CERN Document Server

    Brechenmacher, Frederic

    2011-01-01

    This paper appeals to the figure of \\'Evariste Galois for investigating the gates between mathematics and their "publics." The figure of Galois draws some lines of/within mathematics for/from the outside of mathematics and these lines in turn sketch the silhouette of Galois as a historical figure. The present paper especially investigates the collective categories that have been used in various types of public discourses on Galois's work (e.g. equations, groups, algebra, analysis, France, Germany etc.). In a way, this paper aims at shedding light on the boundaries some individuals drew by getting Galois his gun. It is our aim to highlight the roles of authority some individuals (such as as Picard) took on in regard with the public figure of Galois as well as the roles such authorities assigned to other individuals (such as the mediating role assigned to Jordan as a mediator between Galois's "ideas" and the public). The boundary-works involved by most public references to Galois have underlying them a long-ter...

  18. Lake Wobegon’s Guns: Overestimating Our Gun-Related Competences

    Directory of Open Access Journals (Sweden)

    Emily Stark

    2016-02-01

    Full Text Available The Lake Wobegon Effect is a general tendency for people to overestimate their own abilities. In this study, the authors conducted a large, nationally-representative survey of U.S. citizens to test whether Americans overestimate their own gun-relevant personality traits, gun safety knowledge, and ability to use a gun in an emergency. The authors also tested how gun control attitudes, political identification, gender, and gun experience affect self-perceptions. Consistent with prior research on the Lake Wobegon Effect, participants overestimated their gun-related competencies. Conservatives, males, and pro-gun advocates self-enhanced somewhat more than their counterparts but this effect was primarily due to increased gun experience among these participants. These findings are important to policymakers in the area of gun use, because overconfidence in one’s gun-related abilities may lead to a reduced perceived need for gun training.

  19. Revisiting Pneumatic Nail Gun Trigger Recommendations.

    Science.gov (United States)

    Albers, James; Lowe, Brian; Lipscomb, Hester; Hudock, Stephen; Dement, John; Evanoff, Bradley; Fullen, Mark; Gillen, Matt; Kaskutas, Vicki; Nolan, James; Patterson, Dennis; Platner, James; Pompeii, Lisa; Schoenfisch, Ashley

    2015-03-01

    Use of a pneumatic nail gun with a sequential actuation trigger (SAT) significantly diminishes the risk for acute traumatic injury compared to use of a contact actuation trigger (CAT) nail gun. A theoretically-based increased risk of work-related musculoskeletal disorders from use of a SAT nail gun, relative to CAT, appears unlikely and remains unproven. Based on current knowledge, the use of CAT nail guns cannot be justified as a safe alternative to SAT nail guns. This letter provides a perspective of ergonomists and occupational safety researchers recommending the use of the sequential actuation trigger for all nail gun tasks in the construction industry.

  20. ATA injector-gun calculations

    Energy Technology Data Exchange (ETDEWEB)

    Paul, A.C.

    1981-08-03

    ATA is a pulsed, 50 ns 10 KA, 50 MeV linear induction electron accelerator at LLNL. The ETA could be used as an injector for ATA. However the possibility of building a new injector gun for ATA, raised the question as to what changes from the ETA gun in electrode dimensions or potentials, if any, should be considered. In this report the EBQ code results for the four electrode configurations are reviewed and an attempt is made to determine the geometrical scaling laws appropriate to these ETA type gun geometries. Comparison of these scaling laws will be made to ETA operation. The characteristic operating curves for these geometries will also be presented and the effect of washer position determined. It will be shown that emittance growth will impose a limitation on beam current for a given anode potential before the virtual cathode limit is reached.

  1. Hydrogen Embrittlement of Gun Steel

    Science.gov (United States)

    1987-11-01

    8217s HY80 and HY130 steels were checked for the critical hydrogen concentrations which were determined to be 6 ppm for HY8O steel 8 and 3 ppm for HY130...JOTC FILE COPY AD-A188 972 AD 1 TECHNICAL REPORT ARCCB-TR-87030 HYDROGEN EMBRITTLEMENT OF GUN STEEL F’ GERALD L. SPFNCER DTIC DEC 1 5 1987 NOVEMBER...PtEtIOC COVERED HYDROGEN EMBRITTLEHENT OF GUN STEEL Final OG EOTNME 6. PERFORMINGORO EOTNME 7. A*JTNOR(s) S. CONTRACT OR GRANT NUMBER(&) Gerald L

  2. Advances in light-gas gun technology

    Science.gov (United States)

    Cowan, P. L.; Murphy, J. R.

    1968-01-01

    Constant-area accelerator used with light-gas guns increases the velocity of accelerating projectiles. A disposable accelerator on the muzzle of the gun uses the energy and momentum of a primary projectile, launched by the gun, to achieve high velocities of a light secondary projectile accelerated from rest in the accelerator.

  3. Liquid Propellants for Advanced Gun Ammunitions

    Directory of Open Access Journals (Sweden)

    K. P. Rao

    1987-01-01

    Full Text Available With constant improvements, the conventional solid propellants for guns have almost reached their limit in performance. Liquid gun propellants are promising new comers capable of surpassing these performance limits and have numerous advantages over solid propellants. A method has been worked out to predict the internal ballistics of a liquid propellant gun and illustrated in a typical application.

  4. Definition of a core module for the nuclear retrograde response to altered organellar gene expression identifies GLK overexpressors as gun mutants.

    Science.gov (United States)

    Leister, Dario; Kleine, Tatjana

    2016-07-01

    Retrograde signaling can be triggered by changes in organellar gene expression (OGE) induced by inhibitors such as lincomycin (LIN) or mutations that perturb OGE. Thus, an insufficiency of the organelle-targeted prolyl-tRNA synthetase PRORS1 in Arabidopsis thaliana activates retrograde signaling and reduces the expression of nuclear genes for photosynthetic proteins. Recently, we showed that mTERF6, a member of the so-called mitochondrial transcription termination factor (mTERF) family, is involved in the formation of chloroplast (cp) isoleucine-tRNA. To obtain further insights into its functions, co-expression analysis of MTERF6, PRORS1 and two other genes for organellar aminoacyl-tRNA synthetases was conducted. The results suggest a prominent role of mTERF6 in aminoacylation activity, light signaling and seed storage. Analysis of changes in whole-genome transcriptomes in the mterf6-1 mutant showed that levels of nuclear transcripts for cp OGE proteins were particularly affected. Comparison of the mterf6-1 transcriptome with that of prors1-2 showed that reduced aminoacylation of proline (prors1-2) and isoleucine (mterf6-1) tRNAs alters retrograde signaling in similar ways. Database analyses indicate that comparable gene expression changes are provoked by treatment with LIN, norflurazon or high light. A core OGE response module was defined by identifying genes that were differentially expressed under at least four of six conditions relevant to OGE signaling. Based on this module, overexpressors of the Golden2-like transcription factors GLK1 and GLK2 were identified as genomes uncoupled mutants.

  5. Enhanced anti-tumor effect of a gene gun-delivered DNA vaccine encoding the human papillomavirus type 16 oncoproteins genetically fused to the herpes simplex virus glycoprotein D

    Directory of Open Access Journals (Sweden)

    M.O. Diniz

    2011-05-01

    Full Text Available Anti-cancer DNA vaccines have attracted growing interest as a simple and non-invasive method for both the treatment and prevention of tumors induced by human papillomaviruses. Nonetheless, the low immunogenicity of parenterally administered vaccines, particularly regarding the activation of cytotoxic CD8+ T cell responses, suggests that further improvements in both vaccine composition and administration routes are still required. In the present study, we report the immune responses and anti-tumor effects of a DNA vaccine (pgD-E7E6E5 expressing three proteins (E7, E6, and E5 of the human papillomavirus type 16 genetically fused to the glycoprotein D of the human herpes simplex virus type 1, which was administered to mice by the intradermal (id route using a gene gun. A single id dose of pgD-E7E6E5 (2 µg/dose induced a strong activation of E7-specific interferon-γ (INF-γ-producing CD8+ T cells and full prophylactic anti-tumor effects in the vaccinated mice. Three vaccine doses inhibited tumor growth in 70% of the mice with established tumors. In addition, a single vaccine dose consisting of the co-administration of pgD-E7E6E5 and the vector encoding interleukin-12 or granulocyte-macrophage colony-stimulating factor further enhanced the therapeutic anti-tumor effects and conferred protection to 60 and 50% of the vaccinated mice, respectively. In conclusion, id administration of pgD-E7E6E5 significantly enhanced the immunogenicity and anti-tumor effects of the DNA vaccine, representing a promising administration route for future clinical trials.

  6. Identification and molecular characterization of the second Chlamydomonas gun4 mutant, gun4-II [v2; ref status: indexed, http://f1000r.es/1id

    Directory of Open Access Journals (Sweden)

    Phillip B Grovenstein

    2013-07-01

    Full Text Available The green micro-alga Chlamydomonas reinhardtii is an elegant model organism to study oxygenic photosynthesis. Chlorophyll (Chl and heme are major tetrapyrroles that play an essential role in photosynthesis and respiration. These tetrapyrroles are synthesized via a common branched pathway that involves mainly enzymes, encoded by nuclear genes. One of the enzymes in the pathway is Mg chelatase (MgChel. MgChel catalyzes insertion of Mg2+ into protoporphyrin IX (PPIX, proto to form Magnesium-protoporphyrin IX (MgPPIX, Mgproto, the first biosynthetic intermediate in the Chl branch. The GUN4 (genomes uncoupled 4 protein is not essential for the MgChel activity but has been shown to significantly stimulate its activity. We have isolated a light sensitive mutant, 6F14, by random DNA insertional mutagenesis. 6F14 cannot tolerate light intensities higher than 90-100 μmol photons m-2 s-1. It shows a light intensity dependent progressive photo-bleaching. 6F14 is incapable of photo-autotrophic growth under light intensity higher than 100 μmol photons m-2 s-1. PCR based analyses show that in 6F14 the insertion of the plasmid outside the GUN4 locus has resulted in a genetic rearrangement of the GUN4 gene and possible deletions in the genomic region flanking the GUN4 gene. Our gun4 mutant has a Chl content very similar to that in the wild type in the dark and is very sensitive to fluctuations in the light intensity in the environment unlike the earlier identified Chlamydomonas gun4 mutant. Complementation with a functional copy of the GUN4 gene restored light tolerance, Chl biosynthesis and photo-autotrophic growth under high light intensities in 6F14. 6F14 is the second gun4 mutant to be identified in C. reinhardtii. Additionally, we show that our two gun4 complements over-express the GUN4 protein and show a higher Chl content per cell compared to that in the wild type strain.

  7. A gasdynamic gun driven by gaseous detonation

    Science.gov (United States)

    Li, Jinping; Chen, Hong; Zhang, Shizhong; Zhang, Xiaoyuan; Yu, Hongru

    2016-01-01

    A gasdynamic gun driven by gaseous detonation was developed to address the disadvantages of the insufficient driving capability of high-pressure gas and the constraints of gunpowder. The performance of this gasdynamic gun was investigated through experiments and numerical simulations. Much more powerful launching capability was achieved by this gun relative to a conventional high-pressure gas gun, owing to the use of the chemical energy of the driver gas. To achieve the same launching condition, the initial pressure required for this gun was an order of magnitude lower than that for a gun driven by high-pressure H2. Because of the presence of the detonation, however, a more complex internal ballistic process of this gun was observed. Acceleration of projectiles for this gun was accompanied by a series of impulse loads, in contrast with the smooth acceleration for a conventional one, which indicates that this gun should be used conditionally. The practical feasibility of this gun was verified by experiments. The experiments demonstrated the convenience of taking advantage of the techniques developed for detonation-driven shock tubes and tunnels.

  8. Effects of a gun dealer's change in sales practices on the supply of guns to criminals.

    Science.gov (United States)

    Webster, Daniel W; Vernick, Jon S; Bulzacchelli, Maria T

    2006-09-01

    Licensed gun dealers are a major conduit for gun trafficking. Prior to May 1999, a single gun store sold more than half of the guns recovered from criminals in Milwaukee, WI, shortly following retail sale. On May 10, 1999, the store stopped selling small, inexpensive handguns popular with criminals, often called "Saturday night specials." The purpose of this study was to estimate the effect of this gun store's changed sales practices on criminals' acquisition of new guns. We used an interrupted time-series design with comparisons to test for changes in the number of guns that police recovered from criminals within a year of retail sale following the gun dealer's new sales policy. The dealer's changed sales policy was associated with a 96% decrease in recently sold, small, inexpensive handguns use in crime in Milwaukee, a 73% decrease in crime guns recently sold by this dealer, and a 44% decrease in the flow of all new, trafficked guns to criminals in Milwaukee. The findings demonstrate the substantial impact that a single gun store's sales practices can have on the supply of new guns to criminals. Proposed anti-gun-trafficking efforts in other cities could benefit from targeting problem retail outlets.

  9. GUN1, a Jack-Of-All-Trades in Chloroplast Protein Homeostasis and Signaling

    Science.gov (United States)

    Colombo, Monica; Tadini, Luca; Peracchio, Carlotta; Ferrari, Roberto; Pesaresi, Paolo

    2016-01-01

    The GENOMES UNCOUPLED 1 (GUN1) gene has been reported to encode a chloroplast-localized pentatricopeptide-repeat protein, which acts to integrate multiple indicators of plastid developmental stage and altered plastid function, as part of chloroplast-to-nucleus retrograde communication. However, the molecular mechanisms underlying signal integration by GUN1 have remained elusive, up until the recent identification of a set of GUN1-interacting proteins, by co-immunoprecipitation and mass-spectrometric analyses, as well as protein–protein interaction assays. Here, we review the molecular functions of the different GUN1 partners and propose a major role for GUN1 as coordinator of chloroplast translation, protein import, and protein degradation. This regulatory role is implemented through proteins that, in most cases, are part of multimeric protein complexes and whose precise functions vary depending on their association states. Within this framework, GUN1 may act as a platform to promote specific functions by bringing the interacting enzymes into close proximity with their substrates, or may inhibit processes by sequestering particular pools of specific interactors. Furthermore, the interactions of GUN1 with enzymes of the tetrapyrrole biosynthesis (TPB) pathway support the involvement of tetrapyrroles as signaling molecules in retrograde communication. PMID:27713755

  10. A two-Frequency RF Photocathode Gun

    Energy Technology Data Exchange (ETDEWEB)

    Dowell, D.H. E-mail: dowell@slac.stanford.edu; Ferrario, M.; Kimura, T.; Lewellen, J.; Limborg, C.; Raimondi, P.; Schmerge, J.F.; Serafini, L.; Smith, T.; Young, L

    2004-08-01

    In this paper we resurrect an idea originally proposed by Serafini (Nucl. Instr. and Meth. A 318 (1992) 301) in 1992 for an RF photocathode gun capable of operating simultaneously at the fundamental frequency and a higher frequency harmonic. Driving the gun at two frequencies with the proper field ratio and relative phase produces a beam with essentially no RF emittance and a linear longitudinal phase space distribution. Such a gun allows a completely new range of operating parameters for controlling space charge emittance growth. In addition, the linear longitudinal phase space distribution aids in bunch compression. This paper will compare results of simulations for the two-frequency gun with the standard RF gun and the unique properties of the two-frequency gun will be discussed.

  11. A Two-Frequency RF Photocathode Gun

    Energy Technology Data Exchange (ETDEWEB)

    Dowell, D.

    2004-11-05

    In this paper we resurrect an idea originally proposed by Serafini[1] in 1992 for an RF photocathode gun capable of operating simultaneously at the fundamental frequency and a higher frequency harmonic. Driving the gun at two frequencies with the proper field ratio and relative phase produces a beam with essentially no rf emittance and a linear longitudinal phase space distribution. Such a gun allows a completely new range of operating parameters for controlling space charge emittance growth. In addition, the linear longitudinal phase space distribution aids in bunch compression. This paper will compare results of simulations for the two-frequency gun with the standard rf gun, and the unique properties of the two-frequency gun will be discussed.

  12. 77 FR 37834 - Revocation of Certain Requirements Pertaining to Caps Intended for Use With Toy Guns and Toy Guns...

    Science.gov (United States)

    2012-06-25

    ... Guns and Toy Guns Not Intended for Use With Caps AGENCY: Consumer Product Safety Commission. ACTION... use with toy guns and toy guns not intended for use with caps, which were included in the regulations... revoke our existing banning regulations pertaining to caps intended for use with toy guns and toy...

  13. 78 FR 66840 - Revocation of Certain Requirements Pertaining to Caps Intended for Use With Toy Guns and Toy Guns...

    Science.gov (United States)

    2013-11-07

    ... Guns and Toy Guns Not Intended for Use With Caps AGENCY: Consumer Product Safety Commission. ACTION...-producing toys. Existing CPSC regulations pertaining to caps intended for use with toy guns refer to... intended for use with toy guns and toy guns not intended for use with caps. The final rule is...

  14. Racism, gun ownership and gun control: biased attitudes in US whites may influence policy decisions.

    Science.gov (United States)

    O'Brien, Kerry; Forrest, Walter; Lynott, Dermot; Daly, Michael

    2013-01-01

    Racism is related to policies preferences and behaviors that adversely affect blacks and appear related to a fear of blacks (e.g., increased policing, death penalty). This study examined whether racism is also related to gun ownership and opposition to gun controls in US whites. The most recent data from the American National Election Study, a large representative US sample, was used to test relationships between racism, gun ownership, and opposition to gun control in US whites. Explanatory variables known to be related to gun ownership and gun control opposition (i.e., age, gender, education, income, conservatism, anti-government sentiment, southern vs. other states, political identification) were entered in logistic regression models, along with measures of racism, and the stereotype of blacks as violent. Outcome variables included; having a gun in the home, opposition to bans on handguns in the home, support for permits to carry concealed handguns. After accounting for all explanatory variables, logistic regressions found that for each 1 point increase in symbolic racism there was a 50% increase in the odds of having a gun at home. After also accounting for having a gun in the home, there was still a 28% increase in support for permits to carry concealed handguns, for each one point increase in symbolic racism. The relationship between symbolic racism and opposition to banning handguns in the home (OR1.27 CI 1.03,1.58) was reduced to non-significant after accounting for having a gun in the home (OR1.17 CI.94,1.46), which likely represents self-interest in retaining property (guns). Symbolic racism was related to having a gun in the home and opposition to gun control policies in US whites. The findings help explain US whites' paradoxical attitudes towards gun ownership and gun control. Such attitudes may adversely influence US gun control policy debates and decisions.

  15. Racism, gun ownership and gun control: biased attitudes in US whites may influence policy decisions.

    Directory of Open Access Journals (Sweden)

    Kerry O'Brien

    Full Text Available OBJECTIVE: Racism is related to policies preferences and behaviors that adversely affect blacks and appear related to a fear of blacks (e.g., increased policing, death penalty. This study examined whether racism is also related to gun ownership and opposition to gun controls in US whites. METHOD: The most recent data from the American National Election Study, a large representative US sample, was used to test relationships between racism, gun ownership, and opposition to gun control in US whites. Explanatory variables known to be related to gun ownership and gun control opposition (i.e., age, gender, education, income, conservatism, anti-government sentiment, southern vs. other states, political identification were entered in logistic regression models, along with measures of racism, and the stereotype of blacks as violent. Outcome variables included; having a gun in the home, opposition to bans on handguns in the home, support for permits to carry concealed handguns. RESULTS: After accounting for all explanatory variables, logistic regressions found that for each 1 point increase in symbolic racism there was a 50% increase in the odds of having a gun at home. After also accounting for having a gun in the home, there was still a 28% increase in support for permits to carry concealed handguns, for each one point increase in symbolic racism. The relationship between symbolic racism and opposition to banning handguns in the home (OR1.27 CI 1.03,1.58 was reduced to non-significant after accounting for having a gun in the home (OR1.17 CI.94,1.46, which likely represents self-interest in retaining property (guns. CONCLUSIONS: Symbolic racism was related to having a gun in the home and opposition to gun control policies in US whites. The findings help explain US whites' paradoxical attitudes towards gun ownership and gun control. Such attitudes may adversely influence US gun control policy debates and decisions.

  16. Gun Control in Australia: A Criminological Perspective

    Directory of Open Access Journals (Sweden)

    Rick Sarre

    2015-11-01

    Full Text Available In recent months there has been an upsurge in contributions to the popular press from social commentators insisting that guns make our nation safer. This essay questions these assertions. The paper provides evidence to support a contrary affirmation: that is, in order to have a reduction in gun violence, there needs to be a reduction in the number of guns generally, and a continuation of the legal controls that currently shape firearms policy in Australia.

  17. Cost Estimate for Gun Liner Emplacement

    Science.gov (United States)

    2011-08-01

    forge to near net outer diameter shape: 85-in long 3. Heat treat: quench and temper 4. Straighten to 0.005 in runout 5. Stress relieve 6. Grind ...steady rest 7. Cylindrically grind outer diameter (tapered) 8. Gun drill breech 9. Gun drill barrel inner diameter Detonation Velocity, Vd Gun...1.25-in inner diameter. Electrochemical machining (ECM) is already being employed to rifle M242 steel barrels by Alliant Techsystems (ATK). With this

  18. Research on Hot Gunning Repairing in Laboratory

    Institute of Scientific and Technical Information of China (English)

    CAO Feng; LONG Shigang; MENG Qingmin; SUN Jialin; HONG Yanruo

    2003-01-01

    The lining of blast furnace may be damaged partly,so that gunning repair is needed. The bonding strength of boundary surface between the repairing layer and remained lining of blast furnace has been studied by thermal simulation.The factors influencing the bonding strength are the ingredient gunning repair temperature,remained lining condition and water content of gunning refractory.The bonding strength decreases with the increases of remained lining temperature.

  19. Conceptual Design for CLIC Gun Pulser

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Tao [SLAC National Accelerator Lab., Menlo Park, CA (United States)

    2016-01-08

    The Compact Linear Collider (CLIC) is a proposed future electron-positron collider, designed to perform collisions at energies from 0.5 to 5 TeV, with a nominal design optimized for 3 TeV (Dannheim, 2012). The Drive Beam Accelerator consists of a thermionic DC gun, bunching section and an accelerating section. The thermionic gun needs deliver a long (~143us) pulse of current into the buncher. A pulser is needed to drive grid of the gun to generate a stable current output. This report explores the requirements of the gun pulser and potential solutions to regulate grid current.

  20. Community gun safety in Central Pennsylvania.

    Science.gov (United States)

    Wargo, Christina; Erdman, Deborah A; Smith, Jill Gray; Widom, Kenneth; Reardon, Judith

    2013-01-01

    Firearm-related injuries are a public health issue in the United States. In rural Pennsylvania, it is a familiar way of life to have a gun or guns in the home. Safety behaviors along with gun storage in the home, specifically where there are young children (aged 6 years and younger), are a concern for this level I regional resource center in rural Pennsylvania. Head Start families were surveyed regarding gun safety habits before and after safety educational activities. A noteworthy number of families reported changing behaviors regarding better safety habits for storing and use of firearms in the home postsurvey.

  1. Ion tracking in photocathode rf guns

    Directory of Open Access Journals (Sweden)

    John W. Lewellen

    2002-02-01

    Full Text Available Projected next-generation linac-based light sources, such as PERL or the TESLA free-electron laser, generally assume, as essential components of their injector complexes, long-pulse photocathode rf electron guns. These guns, due to their design rf pulse durations of many milliseconds to continuous wave, may be more susceptible to ion bombardment damage of their cathodes than conventional rf guns, which typically use rf pulses of microsecond duration. This paper explores this possibility in terms of ion propagation within the gun, and presents a basis for future study of the subject.

  2. From gun politics to self-defense politics: a feminist critique of the great gun debate.

    Science.gov (United States)

    Carlson, Jennifer D

    2014-03-01

    This article calls attention to a problematic binary produced by public debates surrounding gun rights and gun control-namely, that women must choose armed self-protection or no self-protection at all. I argue that both anti- and pro-gun discourses, drawing on and reproducing race and class privileges, use assumptions about women's physical inferiority to further their agendas. I highlight how both sides have used guns as the proxy for self-defense and conclude by calling for a shift in public discourse to focus on the broader question of the right to self-defense rather than the narrower question of gun rights.

  3. Electromagnetic Gun With Commutated Coils

    Science.gov (United States)

    Elliott, David G.

    1991-01-01

    Proposed electromagnetic gun includes electromagnet coil, turns of which commutated in sequence along barrel. Electrical current fed to two armatures by brushes sliding on bus bars in barrel. Interaction between armature currents and magnetic field from coil produces force accelerating armature, which in turn, pushes on projectile. Commutation scheme chosen so magnetic field approximately coincides and moves with cylindrical region defined by armatures. Scheme has disadvantage of complexity, but in return, enables designer to increase driving magnetic field without increasing armature current. Attainable muzzle velocity increased substantially.

  4. Crafting a Gauss Gun Demonstration

    Science.gov (United States)

    Blodgett, Matthew E.; Blodgett, E. D.

    2006-12-01

    A Gauss Gun launches a ferromagnetic projectile using a pulsed electromagnet. This demonstration provides a nice counterpoint to the popular Thompson's jumping ring demonstration, which launches a nonferromagnetic ring via repulsion of an induced current. The pulsed current must be short enough in duration so that the projectile is not retarded by lingering current in the launch solenoid, but also large enough to provide a suitably impressive velocity. This project involved an iterative design process, as we worked through balancing all the different design criteria. We recommend it as a very nice electronics design project which will produce a very portable and enjoyable demonstration. AAPT sponsor Earl Blodgett.

  5. The Xygra gun simulation tool.

    Energy Technology Data Exchange (ETDEWEB)

    Garasi, Christopher Joseph; Lamppa, Derek C.; Aubuchon, Matthew S.; Shirley, David Noyes; Robinson, Allen Conrad; Russo, Thomas V.

    2008-12-01

    Inductive electromagnetic launchers, or coilguns, use discrete solenoidal coils to accelerate a coaxial conductive armature. To date, Sandia has been using an internally developed code, SLINGSHOT, as a point-mass lumped circuit element simulation tool for modeling coilgun behavior for design and verification purposes. This code has shortcomings in terms of accurately modeling gun performance under stressful electromagnetic propulsion environments. To correct for these limitations, it was decided to attempt to closely couple two Sandia simulation codes, Xyce and ALEGRA, to develop a more rigorous simulation capability for demanding launch applications. This report summarizes the modifications made to each respective code and the path forward to completing interfacing between them.

  6. Concepts for a short wavelength rf gun

    Science.gov (United States)

    Kuzikov, S. V.; Shchelkunov, S.; Vikharev, A. A.

    2017-03-01

    Three concepts of an rf gun to be operated at 0.1-10 mm wavelengths are considered. In all the concepts, the rf system exploits an accelerating traveling wave. In comparison with a classical decimeter standing-wave rf gun, we analyze the advantages of new concepts, available rf sources, and achievable beam parameters.

  7. On the theory of photocathode rf guns

    Institute of Scientific and Technical Information of China (English)

    GAO Jie

    2009-01-01

    In this paper we give a set of analytical formulae to describe the characteristics of photocathode rf guns at any rf frequencies, such as energy, energy spread, bunch length, out going current, and emittance etc.as functions of the laser injection phase, which are useful in the design and practical operation of rf guns.

  8. Gun Control: The Debate and Public Policy.

    Science.gov (United States)

    Watkins, Christine

    1997-01-01

    Provides an overview and background information on the debate over gun control, as well as several teaching ideas. Handouts include a list of related topics drawn from various disciplines (economics, U.S. history), seven arguments for and against gun control, and a set of policy evaluation guidelines. (MJP)

  9. Interpreting the empirical evidence on illegal gun market dynamics.

    Science.gov (United States)

    Braga, Anthony A; Wintemute, Garen J; Pierce, Glenn L; Cook, Philip J; Ridgeway, Greg

    2012-10-01

    Thousands of Americans are killed by gunfire each year, and hundreds of thousands more are injured or threatened with guns in robberies and assaults. The burden of gun violence in urban areas is particularly high. Critics suggest that the results of firearm trace data and gun trafficking investigation studies cannot be used to understand the illegal supply of guns to criminals and, therefore, that regulatory and enforcement efforts designed to disrupt illegal firearms markets are futile in addressing criminal access to firearms. In this paper, we present new data to address three key arguments used by skeptics to undermine research on illegal gun market dynamics. We find that criminals rely upon a diverse set of illegal diversion pathways to acquire guns, gun traffickers usually divert small numbers of guns, newer guns are diverted through close-to-retail diversions from legal firearms commerce, and that a diverse set of gun trafficking indicators are needed to identify and shut down gun trafficking pathways.

  10. Sequential injection gas guns for accelerating projectiles

    Science.gov (United States)

    Lacy, Jeffrey M [Idaho Falls, ID; Chu, Henry S [Idaho Falls, ID; Novascone, Stephen R [Idaho Falls, ID

    2011-11-15

    Gas guns and methods for accelerating projectiles through such gas guns are described. More particularly, gas guns having a first injection port located proximate a breech end of a barrel and a second injection port located longitudinally between the first injection port and a muzzle end of the barrel are described. Additionally, modular gas guns that include a plurality of modules are described, wherein each module may include a barrel segment having one or more longitudinally spaced injection ports. Also, methods of accelerating a projectile through a gas gun, such as injecting a first pressurized gas into a barrel through a first injection port to accelerate the projectile and propel the projectile down the barrel past a second injection port and injecting a second pressurized gas into the barrel through the second injection port after passage of the projectile and to further accelerate the projectile are described.

  11. New Electron Gun System for BEPCII

    CERN Document Server

    Liu, Bo; Long Chi, Yun; Zhang, Chuang

    2005-01-01

    The new electron gun system for BEPCII has been put into operation since Nov. 2004. The article describes the design, experiment and operation of this new system. The design current of the gun is 10 A for the pulse lengths of 1 ns, 2.5 ns and 1 μs with repetition rate of 50 Hz. The gun is operated with a pulsed high voltage power supply which can provide up to 200 kV high voltage. Computer simulations have been carried out in the design stage, including simulation of the gun geometry and beam transportation. Some important relation curves are obtained during the experiment. Two-bunch operation is available and some elementary tests have been performed. New scheme of the gun control system based on EPICS is also presented. The real operation shows that the design and manufacturing is basically successful.

  12. ERLP Gun Commissioning Beamline Design

    CERN Document Server

    Holder, D J; Hannon, F E

    2004-01-01

    The 4GLS project is a novel next-generation solution for a UK national light source. It is based on an energy recovery linac (ERL) operating at high average beam currents up to 100 mA and with compression schemes producing pulses in the 10 - 100 fs range. This challenging accelerator technology, new to Europe, necessitates a significant R&D programme and a major part of this is a low-energy prototype, the ERLP, which is currently under construction at Daresbury Laboratory, in the north-west of England. The first components of ERLP to be built will be the DC photocathode gun and low-energy beam transport and diagnostics. The gun will initially be operated with a diagnostic beamline in order to measure the properties of the high-brightness beams generated as fully as possible. This will allow comparison of its performance with the results of multi-particle tracking codes, prior to its integration into the ERLP machine. The diagnostic beamline will include diagnostics for measuring the transverse and longitu...

  13. Gun Violence, Mental Illness, And Laws That Prohibit Gun Possession: Evidence From Two Florida Counties

    Science.gov (United States)

    Swanson, Jeffrey W.; Easter, Michele M.; Robertson, Allison G.; Swartz, Marvin S.; Alanis-Hirsch, Kelly; Moseley, Daniel; Dion, Charles; Petrila, John

    2016-01-01

    Gun violence kills about ninety people every day in the United States, a toll measured in wasted and ruined lives and with an annual economic price tag exceeding $200 billion. Some policy makers suggest that reforming mental health care systems and improving point-of-purchase background checks to keep guns from mentally disturbed people will address the problem. Epidemiological research shows that serious mental illness contributes little to the risk of interpersonal violence but is a strong factor in suicide, which accounts for most firearm fatalities. Meanwhile, the effectiveness of gun restrictions focused on mental illness remains poorly understood. This article examines gun-related suicide and violent crime in people with serious mental illnesses, and whether legal restrictions on firearm sales to people with a history of mental health adjudication are effective in preventing gun violence. Among the study population in two large Florida counties, we found that 62 percent of violent gun crime arrests and 28 percent of gun suicides involved individuals not legally permitted to have a gun at the time. Suggested policy reforms include enacting risk-based gun removal laws and prohibiting guns from people involuntarily detained in short-term psychiatric hospitalizations. PMID:27269024

  14. Gun Violence Following Inpatient Psychiatric Treatment: Offense Characteristics, Sources of Guns, and Number of Victims.

    Science.gov (United States)

    Kivisto, Aaron J

    2017-06-01

    This study presents data on the relative contribution to gun violence by people with a history of inpatient psychiatric treatment and on federal efforts to deter presumptively dangerous persons from obtaining firearms, information useful for analyzing the potential public health benefits of gun policies targeting people with serious mental illness. The study also estimates the reduction in gun violence victims that would be expected if individuals with a previous psychiatric hospitalization were prohibited from purchasing firearms. Data from 838 violent gun offenders from a nationally representative sample of state prison inmates were analyzed. Those with and without a history of psychiatric hospitalization were compared on a range of offense characteristics, including relationship to the victim, number of victims, location of the offense, and source of firearms. Inmates with a history of hospitalization constituted 12% of all violent gun offenders and accounted for 13% of the sample's victims. They were less likely than those without a previous hospitalization to victimize strangers (odds ratio=.52) and were no more likely to commit gun violence in public or to have multiple victims. Among those with previous hospitalizations, 78% obtained guns from sources not subject to federal background checks. Of the total 1,041 victims of gun violence, only 3% were victimized by participants with a history of hospitalization who obtained guns from currently regulated sources. Prohibiting all individuals with a history of psychiatric hospitalization from purchasing firearms, absent expanded background checks, was estimated to reduce the number of gun violence victims by only 3%.

  15. Gun Violence, Mental Illness, And Laws That Prohibit Gun Possession: Evidence From Two Florida Counties.

    Science.gov (United States)

    Swanson, Jeffrey W; Easter, Michele M; Robertson, Allison G; Swartz, Marvin S; Alanis-Hirsch, Kelly; Moseley, Daniel; Dion, Charles; Petrila, John

    2016-06-01

    Gun violence kills about ninety people every day in the United States, a toll measured in wasted and ruined lives and with an annual economic price tag exceeding $200 billion. Some policy makers suggest that reforming mental health care systems and improving point-of-purchase background checks to keep guns from mentally disturbed people will address the problem. Epidemiological research shows that serious mental illness contributes little to the risk of interpersonal violence but is a strong factor in suicide, which accounts for most firearm fatalities. Meanwhile, the effectiveness of gun restrictions focused on mental illness remains poorly understood. This article examines gun-related suicide and violent crime in people with serious mental illnesses, and whether legal restrictions on firearm sales to people with a history of mental health adjudication are effective in preventing gun violence. Among the study population in two large Florida counties, we found that 62 percent of violent gun crime arrests and 28 percent of gun suicides involved individuals not legally permitted to have a gun at the time. Suggested policy reforms include enacting risk-based gun removal laws and prohibiting guns from people involuntarily detained in short-term psychiatric hospitalizations.

  16. Homopolar Gun for Pulsed Spheromak Fusion Reactors II

    Energy Technology Data Exchange (ETDEWEB)

    Fowler, T

    2004-06-14

    A homopolar gun is discussed that could produce the high currents required for pulsed spheromak fusion reactors even with unit current amplification and open field lines during injection, possible because close coupling between the gun and flux conserver reduces gun losses to acceptable levels. Example parameters are given for a gun compatible with low cost pulsed reactors and for experiments to develop the concept.

  17. Alignment Fixtures For Vacuum-Plasma-Spray Gun

    Science.gov (United States)

    Woodford, William H.; Mckechnie, Timothy N.; Power, Christopher A.; Daniel, Ronald L., Jr.

    1993-01-01

    Fixtures for alignment of vacuum-plasma-spray guns built. Each fixture designed to fit specific gun and holds small, battery-powered laser on centerline of gun. Laser beam projects small red dot where centerline intersects surface of workpiece to be sprayed. After laser beam positioned on surface of workpiece, fixture removed from gun and spraying proceeds.

  18. Ready, Fire, Aim: The College Campus Gun Fight

    Science.gov (United States)

    Birnbaum, Robert

    2013-01-01

    The question of whether guns should be permitted on college and university campuses in the United States reflects the tension between two competing perspectives. America has both a robust gun culture and an equally robust (if less well known) gun-control culture. The gun culture is as American as apple pie: There may be as many as 300 million…

  19. Gun Safety Management with Patients at Risk for Suicide

    Science.gov (United States)

    Simon, Robert I.

    2007-01-01

    Guns in the home are associated with a five-fold increase in suicide. All patients at risk for suicide must be asked if guns are available at home or easily accessible elsewhere, or if they have intent to buy or purchase a gun. Gun safety management requires a collaborative team approach including the clinician, patient, and designated person…

  20. Ready, Fire, Aim: The College Campus Gun Fight

    Science.gov (United States)

    Birnbaum, Robert

    2013-01-01

    The question of whether guns should be permitted on college and university campuses in the United States reflects the tension between two competing perspectives. America has both a robust gun culture and an equally robust (if less well known) gun-control culture. The gun culture is as American as apple pie: There may be as many as 300 million…

  1. Gun Safety Management with Patients at Risk for Suicide

    Science.gov (United States)

    Simon, Robert I.

    2007-01-01

    Guns in the home are associated with a five-fold increase in suicide. All patients at risk for suicide must be asked if guns are available at home or easily accessible elsewhere, or if they have intent to buy or purchase a gun. Gun safety management requires a collaborative team approach including the clinician, patient, and designated person…

  2. Gun Violence, mental health, and Connecticut physicians.

    Science.gov (United States)

    Dodds, Peter R; Anderson, Caitlyn O; Dodds, Jon H

    2014-01-01

    While there is a public perception that gun violence is associated with mental illness we present evidence that it is a complex public health problem which defies simple characterizations and solutions. Only a small percentage of individuals with mental illness are at risk for extreme violence and they account for only a small percentage of gun-related homicides. Individuals who are at risk for gun violence are difficult to identify and successfully treat. The incidence, and perhaps the demographics, of gun violence vary substantially from state to state. We make a case for Connecticut physicians to study gun violence at the state level. We recommend that Connecticut physicians promote and expand upon the American Academy of Pediatrics' recommendation for creating a "safe home environment. "We suggest that guns be secured in all homes in which there are children. In addition we suggest that guns be voluntarily removed from homes in which there are individuals with a history of violence, threats of violence, depression, drug and/or alcohol abuse, and individuals with major mental illnesses who are not cooperating with therapy.

  3. One nanosecond pulsed electron gun systems

    Energy Technology Data Exchange (ETDEWEB)

    Koontz, R.F.

    1979-02-01

    At SLAC there has been a continuous need for the injection of very short bunches of electrons into the accelerator. Several time-of-flight experiments have used bursts of short pulses during a normal 1.6 micro-second rf acceleration period. Single bunch beam loading experiments made use of a short pulse injection system which included high power transverse beam chopping equipment. Until the equipment described in this paper came on line, the basic grid-controlled gun pulse was limited to a rise time of 7 nanoseconds and a pulse width of 10 nanoseconds. The system described here has a grid-controlled rise time of less than 500 pico-seconds, and a minimum pulse width of less than 1 nanosecond. Pulse burst repetition rate has been demonstrated above 20 MHz during a 1.6 microsecond rf accelerating period. The order-of-magnitude increase in gun grid switching speed comes from a new gun design which minimizes lead inductance and stray capacitance, and also increases gun grid transconductance. These gun improvements coupled with a newly designed fast pulser mounted directly within the gun envelope make possible subnanosecond pulsing of the gun.

  4. Gun ownership and firearm-related deaths.

    Science.gov (United States)

    Bangalore, Sripal; Messerli, Franz H

    2013-10-01

    A variety of claims about possible associations between gun ownership rates, mental illness burden, and the risk of firearm-related deaths have been put forward. However, systematic data on this issue among various countries remain scant. Our objective was to assess whether the popular notion "guns make a nation safer" has any merits. Data on gun ownership were obtained from the Small Arms Survey, and for firearm-related deaths from a European detailed mortality database (World Health Organization), the National Center for Health Statistics, and others. Crime rate was used as an indicator of safety of the nation and was obtained from the United Nations Surveys of Crime Trends. Age-standardized disability-adjusted life-year rates due to major depressive disorder per 100,000 inhabitants with data obtained from the World Health Organization database were used as a putative indicator for mental illness burden in a given country. Among the 27 developed countries, there was a significant positive correlation between guns per capita per country and the rate of firearm-related deaths (r = 0.80; P guns per capita per country and crime rate (r = .33), or between mental illness and crime rate (r = 0.32; P = .11). In a linear regression model with firearm-related deaths as the dependent variable with gun ownership and mental illness as independent covariates, gun ownership was a significant predictor (P guns per capita per country was a strong and independent predictor of firearm-related death in a given country, whereas the predictive power of the mental illness burden was of borderline significance in a multivariable model. Regardless of exact cause and effect, however, the current study debunks the widely quoted hypothesis that guns make a nation safer. Copyright © 2013 Elsevier Inc. All rights reserved.

  5. "Is there a gun in the home?" Assessing the risks of gun ownership in older adults.

    Science.gov (United States)

    Pinholt, Ellen M; Mitchell, Joshua D; Butler, Jane H; Kumar, Harjinder

    2014-06-01

    An important ethical and safety concern that geriatricians, primary care providers, and home health professionals need to address is gun ownership by elderly adults. Those aged 65 and older now have the highest rate of gun ownership in America, and they also have a high prevalence of depression and suicide. Dementia can add additional layers of risk. Even older gun owners who are otherwise intellectually intact may benefit from information about gun safety with the increasing numbers of children being cared for by grandparents. Health professionals should ask patients, "Is there a gun in the home?" in the clinic and during home visits. Healthcare professionals must have knowledge and skills to address safe gun ownership in elderly adults. The 5 L's (Locked, Loaded, Little children, feeling Low, Learned owner) will assist professionals in addressing all aspects of safe ownership. © 2014, Copyright the Authors Journal compilation © 2014, The American Geriatrics Society.

  6. Texas youth stage rally against guns

    Institute of Scientific and Technical Information of China (English)

    Mary; Alice; Robbins; 李小平

    2000-01-01

    Young Texans Against Gun Violence rallied atthe State Capitol on Monday and called for the Legisla-ture to pass laws that would make it more difficult toget guns.“It is time for our state Legislature to pass laws tohelp protect us,”Marianne Moreno,a high school se-nior from the Dallas area,told a crowd of about 125students who attended the“Packing Peace Rally.”“As Texas law stands today,anyone—even acriminal—can walk into a gun show and purchase asemi-automatic weapon or any other type of firearm,...

  7. Evaluation of Smart Gun Technologies preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, D.R.

    1996-01-01

    The Smart Gun Technology Project has a goal to eliminate the capability of an unauthorized user from firing a law enforcement officer`s firearm by implementing {open_quote}smart{close_quote} technologies. Smart technologies are those that can in some manner identify an officer. This report will identify, describe, and grade various technologies as compared to the requirements that were obtained from officers. This report does not make a final recommendation for a smart gun technology, nor does it give the complete design of a smart gun system.

  8. GUN1 Controls Accumulation of the Plastid Ribosomal Protein S1 at the Protein Level and Interacts with Proteins Involved in Plastid Protein Homeostasis.

    Science.gov (United States)

    Tadini, Luca; Pesaresi, Paolo; Kleine, Tatjana; Rossi, Fabio; Guljamow, Arthur; Sommer, Frederik; Mühlhaus, Timo; Schroda, Michael; Masiero, Simona; Pribil, Mathias; Rothbart, Maxi; Hedtke, Boris; Grimm, Bernhard; Leister, Dario

    2016-03-01

    Developmental or metabolic changes in chloroplasts can have profound effects on the rest of the plant cell. Such intracellular responses are associated with signals that originate in chloroplasts and convey information on their physiological status to the nucleus, which leads to large-scale changes in gene expression (retrograde signaling). A screen designed to identify components of retrograde signaling resulted in the discovery of the so-called genomes uncoupled (gun) mutants. Genetic evidence suggests that the chloroplast protein GUN1 integrates signals derived from perturbations in plastid redox state, plastid gene expression, and tetrapyrrole biosynthesis (TPB) in Arabidopsis (Arabidopsis thaliana) seedlings, exerting biogenic control of chloroplast functions. However, the molecular mechanism by which GUN1 integrates retrograde signaling in the chloroplast is unclear. Here we show that GUN1 also operates in adult plants, contributing to operational control of chloroplasts. The gun1 mutation genetically interacts with mutations of genes for the chloroplast ribosomal proteins S1 (PRPS1) and L11. Analysis of gun1 prps1 lines indicates that GUN1 controls PRPS1 accumulation at the protein level. The GUN1 protein physically interacts with proteins involved in chloroplast protein homeostasis based on coimmunoprecipitation experiments. Furthermore, yeast two-hybrid and bimolecular fluorescence complementation experiments suggest that GUN1 might transiently interact with several TPB enzymes, including Mg-chelatase subunit D (CHLD) and two other TPB enzymes known to activate retrograde signaling. Moreover, the association of PRPS1 and CHLD with protein complexes is modulated by GUN1. These findings allow us to speculate that retrograde signaling might involve GUN1-dependent formation of protein complexes.

  9. Waterfowl habitat survey : Canvasback Gun Club : 1964

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes a survey of the submergent and emergent aquatics growing in the marsh on the Canvasback Gun Club in Nevada. The marsh portion of the...

  10. Waterfowl habitat survey : Canvasback Gun Club : 1965

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes a survey of the submergent and emergent aquatics growing in the marsh on the Canvasback Gun Club in Nevada. As stated in previous years of...

  11. Waterfowl habitat survey : Canvasback Gun Club : 1972

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Since the last vegetative survey in 1965, the marsh at Canvasback Gun Club has remained virtually unchanged. The Arthur-Johnson Ponds produced most of the waterfowl...

  12. RF Electron Gun with Driven Plasma Cathode

    CERN Document Server

    Khodak, Igor

    2005-01-01

    It's known that RF guns with plasma cathodes based on solid-state dielectrics are able to generate an intense electron beam. In this paper we describe results of experimental investigation of the single cavity S-band RF gun with driven plasma cathode. The experimental sample of the cathode based on ferroelectric ceramics has been designed. Special design of the cathode permits to separate spatially processes of plasma development and electron acceleration. It has been obtained at RF gun output electron beam with particle energy ~500 keV, pulse current of 4 A and pulse duration of 80 ns. Results of experimental study of beam parameters are referred in. The gun is purposed to be applied as the intense electron beam source for electron linacs.

  13. Arc Plasma Gun With Coaxial Powder Feed

    Science.gov (United States)

    Zaplatynsky, Isidor

    1988-01-01

    Redesigned plasma gun provides improved metallic and ceramic coatings. Particles injected directly through coaxial bore in cathode into central region of plasma jet. Introduced into hotter and faster region of plasma jet.

  14. Detonator assembly for oil well perforating gun

    Energy Technology Data Exchange (ETDEWEB)

    Regalbuto, J.A.

    1981-02-18

    A safe/arm detonator assembly for use with an oil well perforating gun assembly has 2 housing members isolated from well-bore fluid which are rotatable from a safe position wherein a detonator and a booster are held out of alignment, to an armed position wherein the detonator and booster are moved into alignment. The detonator assembly is further arranged to be installed in a well perforating gun assembly such that the gun assembly may be transported with the detonator assembly in the safe position, and rotated to the armed position at the well site without disassembling the gun assembly. A safety pin may protrude from one of the housing members across a cavity between the members to cover and protect the booster from accidental detonation when the detonator assembly is in the safe position. The detonator and booster cavities may be held aligned by a detent ball. 16 claims.

  15. Ballistic Rail Gun Soft Recovery Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Ballistic Rail Gun Soft Recovery Facility accommodates a 155mm Howitzer, fired horizontally into a 104-foot long water trough to slow the projectile and recover...

  16. Uudised : Guns N' Roses Soomes. Valmis ulmeraadio

    Index Scriptorium Estoniae

    2006-01-01

    Ameerika hard-rock-bändi Guns N' Roses kontserdist 5. juulil Hartwall Areenal Soomes. Kord kuus on Ulmeplaatide kodulehekülel www. ulmeplaadid.ee võimalus kuulata ulmeraadiot, kus esitusel eesti kergemuusika

  17. Waterfowl habitat survey : Canvasback Gun Club : 1962

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report is about an investigation that was done to determine the quantity and species of submergent vegetation in the marsh area on the Canvasback Gun Club in...

  18. Uudised : Guns N' Roses Soomes. Valmis ulmeraadio

    Index Scriptorium Estoniae

    2006-01-01

    Ameerika hard-rock-bändi Guns N' Roses kontserdist 5. juulil Hartwall Areenal Soomes. Kord kuus on Ulmeplaatide kodulehekülel www. ulmeplaadid.ee võimalus kuulata ulmeraadiot, kus esitusel eesti kergemuusika

  19. Direct launch using the electric rail gun

    Science.gov (United States)

    Barber, J. P.

    1983-01-01

    The concept explored involves using a large single stage electric rail gun to achieve orbital velocities. Exit aerodynamics, launch package design and size, interior ballistics, system and component sizing and design concepts are treated. Technology development status and development requirements are identified and described. The expense of placing payloads in Earth orbit using conventional chemical rockets is considerable. Chemical rockets are very inefficient in converting chemical energy into payload kinetic energy. A rocket motor is relatively expensive and is usually expended on each launch. In addition specialized and expensive forms of fuel are required. Gun launching payloads directly to orbit from the Earth's surface is a possible alternative. Guns are much more energy efficient than rockets. The high capital cost of the gun installation can be recovered by reusing it over and over again. Finally, relatively inexpensive fuel and large quantities of energy are readily available to a fixed installation on the Earth's surface.

  20. The electric rail gun for space propulsion

    Science.gov (United States)

    Bauer, D. P.; Barber, J. P.; Vahlberg, C. J.

    1981-01-01

    An analytic feasibility investigation of an electric propulsion concept for space application is described. In this concept, quasistatic thrust due to inertial reaction to repetitively accelerated pellets by an electric rail gun is used to propel a spacecraft. The study encompasses the major subsystems required in an electric rail gun propulsion system. The mass, performance, and configuration of each subsystem are described. Based on an analytic model of the system mass and performance, the electric rail gun mission performance as a reusable orbital transfer vehicle (OTV) is analyzed and compared to a 30 cm ion thruster system (BIMOD) and a chemical propulsion system (IUS) for payloads with masses of 1150 kg and 2300 kg. For system power levels in the range from 25 kW(e) to 100 kW(e) an electric rail gun OTV is more attractive than a BIMOD system for low Earth orbit to geosynchronous orbit transfer durations in the range from 20 to 120 days.

  1. Arc-driven rail gun research

    Science.gov (United States)

    Ray, P. K.

    1984-01-01

    The equations describing the performance of an inductively-driven rail gun are analyzed numerically. Friction between the projectile and rails is included through an empirical formulation. The equations are applied to the experiment of Rashleigh and Marshall to obtain an estimate of energy distribution in rail guns as a function of time. The effect of frictional heat dissipation on the bore of the gun is calculated. The mechanism of plasma and projectile acceleration in a dc rail gun is described from a microscopic point of view through the establishment of the Hall field. The plasma conductivity is shown to be a tensor indicating that there is a small component of current parallel to the direction of acceleration. The plasma characteristics are evaluated as a function of plasma mass through a simple fluid mechanical analysis of the plasma. By equating the energy dissipated in the plasma with the radiation heat loss, the properties of the plasma are determined.

  2. Waterfowl habitat survey : Canvasback Gun Club : 1963

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report summarizes a survey of the submergent and emergent aquatics growing in the marsh on the Canvasback Gun Club in Nevada. The marsh portion of the...

  3. Modelling Effectiveness of Machine Gun Fire

    OpenAIRE

    Dutta, D.; S. Sabhanval

    2002-01-01

    Machine gun is an effective infantry weapon which can cause heavy damage to enemy targets, if sited in a tactically favourable position. It can be engaged effectively against both static and moving targets. The paper deals with the determination of target vulnerability under effective machine gun fire considering relevant tactical parameters, eg, target aiming point, trajectory of fire, sweep angle, target frontage, posture, direction of attack, etc.

  4. Modelling Effectiveness of Machine Gun Fire

    Directory of Open Access Journals (Sweden)

    D. Dutta

    2002-04-01

    Full Text Available Machine gun is an effective infantry weapon which can cause heavy damage to enemy targets, if sited in a tactically favourable position. It can be engaged effectively against both static and moving targets. The paper deals with the determination of target vulnerability under effective machine gun fire considering relevant tactical parameters, eg, target aiming point, trajectory of fire, sweep angle, target frontage, posture, direction of attack, etc.

  5. Cobalt-Base Alloy Gun Barrel Study

    Science.gov (United States)

    2014-07-01

    are presented in Section 5. 2. Materials and methods The composition of the cobalt -base alloy (CBA) is presented in Table 1. The production of this... Cobalt -Base Alloy Gun Barrel Study by William S. de Rosset and Jonathan S. Montgomery ARL-RP-0491 July 2014 A reprint...21005-5069 ARL-RP-0491 July 2014 Cobalt -Base Alloy Gun Barrel Study William S. de Rosset and Jonathan S. Montgomery Weapons and Materials

  6. Are "goods for guns" good for the community? An update of a community gun buyback program.

    Science.gov (United States)

    Green, Jonathan; Damle, Rachelle N; Kasper, Rebecca E; Violano, Pina; Manno, Mariann; Nazarey, Pradeep P; Aidlen, Jeremy T; Hirsh, Michael P

    2017-08-01

    Gun violence remains a leading cause of death in the United States. Community gun buyback programs provide an opportunity to dispose of extraneous firearms. The purpose of this study was to understand the demographics, motivation, child access to firearms, and household mental illness of buyback participants in hopes of improving the program's effectiveness. A 2015 Injury Free Coalition for Kids gun buyback program which collaborated with local police departments was studied. We administered a 23-item questionnaire survey to gun buyback participants assessing demographic characteristics, motivation for relinquishing firearms, child firearm accessibility, and mental illness/domestic violence history. A total of 186 individuals from Central/Western Massachusetts turned in 339 weapons. Participants received between US $25 and US $75 in gift cards dependent on what type of gun was turned in, with an average cost of $41/gun. A total of 109 (59%) participants completed the survey. Respondents were mostly white (99%), men (90%) and first-time participants in the program (85.2%). Among survey respondents, 54% turned in firearms "for safety reasons." Respondents reported no longer needing/wanting their weapons (47%) and approximately one in eight participants were concerned the firearm(s) were accessible to children. Most respondents (87%) felt the program encouraged neighborhood awareness of firearm safety. Three of every five participants reported that guns still remained in their homes; additionally, 21% where children could potentially access them and 14% with a history of mental illness/suicide/domestic violence in the home. Gun buybacks can provide a low-cost means of removing unwanted firearms from the community. Most participants felt their homes were safer after turning in the firearm(s). In homes still possessing guns, emphasis on secure gun storage should continue, increasing the safety of children and families. The results of this survey also provided new

  7. A high-brightness thermionic microwave electron gun

    Energy Technology Data Exchange (ETDEWEB)

    Borland, Michael [Stanford Univ., CA (United States)

    1991-02-01

    In a collaborative effort by SSRL, AET Associates, and Varian Associates, a high-brightness microwave electron gun using a thermionic cathode has been designed, built, tested, and installed for use with the SSRL 150 MeV linear accelerator. This thesis discusses the physics behind the design and operation of the gun and associated systems, presenting predictions and experimental tests of the gun`s performance. The microwave gun concept is of increasing interest due to its promise of providing higher-current, lower-emittance electron beams than possible from conventional, DC gun technology. In a DC guns, accelerating gradients are less than 8 MV/m, while those in a microwave gun can exceed 100 MV/m, providing much more rapid initial acceleration, thereby reducing the deleterious effects of space-charge. Microwave guns produce higher momentum beams than DC guns, thus lessening space-charge effects during subsequent beam transport. Typical DC guns produce kinetic energies of 80--400 KeV, compared to 2--3 MeV for the SSRL microwave gun. ``State-of-the-art`` microwave gun designs employ laser-driven photocathodes, providing excellent performance but with greater complexity and monetary costs. A thermionic microwave gun with a magnetic bunching system is comparable in cost and complexity to a conventional system, but provides performance that is orders of magnitude better. Simulations of the SSRL microwave gun predict a normalized RMS emittance at the gun exist of < 10 π • mec • μm for a beam consisting of approximately 50% of the particles emitted from the gun, and having a momentum spread ±10%. These emittances are for up to 5 x 109e- per bunch. Chromatic aberrations in the transport line between the gun and linear accelerator increase this to typically < 30 π • me • μm.

  8. Gun Carrying by High School Students in Boston, MA: Does Overestimation of Peer Gun Carrying Matter?

    Science.gov (United States)

    Hemenway, David; Vriniotis, Mary; Johnson, Renee M.; Miller, Matthew; Azrael, Deborah

    2011-01-01

    This paper investigates: (1) whether high school students overestimate gun carrying by their peers, and (2) whether those students who overestimate peer gun carrying are more likely to carry firearms. Data come from a randomly sampled survey conducted in 2008 of over 1700 high school students in Boston, MA. Over 5% of students reported carrying a…

  9. Gun Carrying by High School Students in Boston, MA: Does Overestimation of Peer Gun Carrying Matter?

    Science.gov (United States)

    Hemenway, David; Vriniotis, Mary; Johnson, Renee M.; Miller, Matthew; Azrael, Deborah

    2011-01-01

    This paper investigates: (1) whether high school students overestimate gun carrying by their peers, and (2) whether those students who overestimate peer gun carrying are more likely to carry firearms. Data come from a randomly sampled survey conducted in 2008 of over 1700 high school students in Boston, MA. Over 5% of students reported carrying a…

  10. Vibration produced by hand-held olive electrical harvesters

    Directory of Open Access Journals (Sweden)

    Emanuele Cerruto

    2012-09-01

    Full Text Available The paper reports the results of some laboratory and field tests aimed at assessing the acceleration levels transmitted to the hand-arm system by electric portable harvesters for olive. Four harvesting heads, different for shape and kinematic system, and five bars, different for diameter, length and material (aluminium and carbon fibre, were used in assembling eleven harvesters. The vibrations were measured in two points, next to the handgrips. The laboratory tests allowed the evaluation of the acceleration levels in standard controlled conditions, while the field tests allowed the assessing of the effects of the tree canopy with respect to the no load running. The laboratory tests showed that in reducing the vibration level plays a major role the kinematic system of the harvesting head and then the bar material. The classical flap-type harvester produced accelerations of around 20 m/s2, while by using a harvesting head with two parts in opposite movement, the accelerations were lowered to about 6 m/s2. The use of carbon fibres for the bars, besides the reduction in weight, produced also a reduction in acceleration (from 21 to 16 m/s2. The field tests proved that the tree canopy had a negative effect on the vibrations transmitted to the hand-arm system, especially when the aluminium bar of small diameter was used.

  11. Absorption Related to Hand-Held Devices in Data Mode

    DEFF Research Database (Denmark)

    Andersen, Jørgen Bach; Nielsen, Jesper Ødum; Pedersen, Gert F.

    2016-01-01

    The human body has an influence on the radiation from handheld devices like smartphones, tablets and laptops, part of the energy is absorbed and the spatial distribution of the radiated part is modified. Previous studies of whole body absorp- tion have mainly been numerical or related to talk mode....... In the present paper an experimental study involving four volunteers and three different devices is performed from 0.5 to 3 GHz. The devices are a laptop, a tablet, and a smartphone all held in the lap. The 3D distribution of radiation is measured. Comparing the integrated power in the case of a person present...... with the device alone allows the determination of the relative absorption in the whole body and the device. In general the absorption varies considerably between devices and as a function of frequency and person. The absorption varies from almost nothing to close to 100%. The shadowing of the body is apparent...

  12. Real-Time Hand-Held Magnetometer Array

    Science.gov (United States)

    2016-04-01

    detection because of their sensitivity in spite of their large size and power consumption. Large batteries are required to power the system, which...metal detector array with real-time processing algorithms that accurately determines the position, depth, and size of magnetic anomalies from...electronics design using a novel digital approach. We achieved order of magnitude reductions in the size and power consumption of total field

  13. Testing of Hand-Held Mine Detection Systems

    Science.gov (United States)

    2015-01-08

    typically lighter weight, easier to operate, and cost less than their dual sensor counterpart. Bottom line, it is up to the application and operator to...3.2 Test Planning. a. Test planning should be initiated early in the acquisition process in order to yield the most cost effective approach to...size, strength, and wearing suitable garments and equipment appropriate to the tasks. Data will be gathered to identify and define the test

  14. 3D interactive topology optimization on hand-held devices

    DEFF Research Database (Denmark)

    Nobel-Jørgensen, Morten; Aage, Niels; Christiansen, Asger Nyman;

    2015-01-01

    This educational paper describes the implementation aspects, user interface design considerations and workflow potential of the recently published TopOpt 3D App. The app solves the standard minimum compliance problem in 3D and allows the user to change design settings interactively at any point i...

  15. Development of plasma cathode electron guns

    Science.gov (United States)

    Oks, Efim M.; Schanin, Peter M.

    1999-05-01

    The status of experimental research and ongoing development of plasma cathode electron guns in recent years is reviewed, including some novel upgrades and applications to various technological fields. The attractiveness of this kind of e-gun is due to its capability of creating high current, broad or focused beams, both in pulsed and steady-state modes of operation. An important characteristic of the plasma cathode electron gun is the absence of a thermionic cathode, a feature which leads to long lifetime and reliable operation even in the presence of aggressive background gas media and at fore-vacuum gas pressure ranges such as achieved by mechanical pumps. Depending on the required beam parameters, different kinds of plasma discharge systems can be used in plasma cathode electron guns, such as vacuum arcs, constricted gaseous arcs, hollow cathode glows, and two kinds of discharges in crossed E×B fields: Penning and magnetron. At the present time, plasma cathode electron guns provide beams with transverse dimension from fractional millimeter up to about one meter, beam current from microamperes to kiloamperes, beam current density up to about 100 A/cm2, pulse duration from nanoseconds to dc, and electron energy from several keV to hundreds of keV. Applications include electron beam melting and welding, surface treatment, plasma chemistry, radiation technologies, laser pumping, microwave generation, and more.

  16. Progress of the Rossendorf SRF Gun Project

    CERN Document Server

    Teichert, J; Büttig, H; Janssen, D; Lehnert, U; Michel, P; Möller, K; Murcek, P; Schneider, C; Schurig, R; Staufenbiel, F; Xiang, R

    2005-01-01

    A superconducting rf photo electron injector (SRF gun) is under development at the Forschungszentrum Rossendorf. The project aims at several issues: improvement of the beam quality for the ELBE superconducting electron linac, demonstration of feasibility of this gun type, investigation of critical components, and parameter studies for future application (BESSY-FEL, 4GLS). In 2005, a substantial progress has been made. The two 3.5-cell niobium cavities for the gun have been delivered from the company ACCEL. The main parts for gun cryostat like vacuum vessel, cryogenic and magnetic shields are ready. Test benches for the cathode cooling system and the cavity tuner are being assembled. The photo cathode preparation lab has been arranged, and the diagnostic beam line has been designed (see T. Kamps et al., this conference). After delivering the gun cavities, their rf properties are being measured at room temperature and the warm tuning is being carried out. The set-up for this treatment and measurement as well as...

  17. The Adhesion and Formation Mechanism of Blast Furnace Gunning Layer

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Basing on the study of the equilibrium relationship of interfacial tension among gunning particles, repaired surface and atmosphere, this test is in a position to draw a conclusion concerning the adhesion mechanism of the gunning refractory and the repaired surface, which illustrates the formation of the bottom gunning layer by moist fine gunning particles on the repaired surface. Also involved within the scope of discussion and probe are the patterns formed under this contacting effect and the formation mechanism of gunning layer. The analytic research regarding the behavior of gunning interface has ascribed the influence upon adhesion intensity to the quality of furnace gunning refractory, the state of the repaired surface and the gunning techniques.

  18. Mole guns in Turkey in 2003-2005.

    Science.gov (United States)

    Yilmaz, Riza; Birincioğlu, Ismail; Cakir, Ismail; Uner, H Bülent; Açikgöz, Dinç; Seçkin, Cetin

    2007-01-01

    This study describes the frequency of mole guns in Turkey by examining the cases sent to the Council of Forensic Medicine of Turkey between 2003 and 2005. In total, 11 mole guns were examined. Mole guns are manufactured to be used as a trap against detrimental animals. Although they are not meant to be used as a firearm, they are able to cause death. Mole guns appearing in regular casework were evaluated in terms of type of the gun, number of barrels, size and caliber, rifling, design, mechanism, fitness for use, legality, and geographical distribution. Ninety-one percent of the guns were 12 gauge. Most commonly they originate from Inner Anatolia. Mole guns are typically handmade. Some examples of injuries and deaths caused by mole guns are also offered.

  19. The Real Costs of Gun Violence

    Energy Technology Data Exchange (ETDEWEB)

    Cook, Philip J. (Duke University)

    2001-03-14

    I will report some of the results in my new book, 'Gun Violence: The Real Costs' (Oxford University Press, 2000; with Jens Ludwig). The problem of gun violence is usually summarized by statistics on deaths and injuries. Those statistics tell only part of the story. All of us bear some of the burden of gun violence, at least in the form of higher taxes and waiting to go through the airport security checks. But that's just the beginning. The extraordinary reductions in lethal violence that occurred during the 1990s help account for rising property values and urban renewal; further reductions are possible and would do still more to enhance the average standard of living. This talk will explain why the economic perspective provides a fresh, useful point of view on violence, and will discuss the technique used to arrive at an estimate of the magnitude of the burden.

  20. Secondary emission electron gun using external primaries

    Science.gov (United States)

    Srinivasan-Rao, Triveni; Ben-Zvi, Ilan

    2009-10-13

    An electron gun for generating an electron beam is provided, which includes a secondary emitter. The secondary emitter includes a non-contaminating negative-electron-affinity (NEA) material and emitting surface. The gun includes an accelerating region which accelerates the secondaries from the emitting surface. The secondaries are emitted in response to a primary beam generated external to the accelerating region. The accelerating region may include a superconducting radio frequency (RF) cavity, and the gun may be operated in a continuous wave (CW) mode. The secondary emitter includes hydrogenated diamond. A uniform electrically conductive layer is superposed on the emitter to replenish the extracted current, preventing charging of the emitter. An encapsulated secondary emission enhanced cathode device, useful in a superconducting RF cavity, includes a housing for maintaining vacuum, a cathode, e.g., a photocathode, and the non-contaminating NEA secondary emitter with the uniform electrically conductive layer superposed thereon.

  1. Secondary emission electron gun using external primaries

    Science.gov (United States)

    Srinivasan-Rao, Triveni; Ben-Zvi, Ilan; Kewisch, Jorg; Chang, Xiangyun

    2007-06-05

    An electron gun for generating an electron beam is provided, which includes a secondary emitter. The secondary emitter includes a non-contaminating negative-electron-affinity (NEA) material and emitting surface. The gun includes an accelerating region which accelerates the secondaries from the emitting surface. The secondaries are emitted in response to a primary beam generated external to the accelerating region. The accelerating region may include a superconducting radio frequency (RF) cavity, and the gun may be operated in a continuous wave (CW) mode. The secondary emitter includes hydrogenated diamond. A uniform electrically conductive layer is superposed on the emitter to replenish the extracted current, preventing charging of the emitter. An encapsulated secondary emission enhanced cathode device, useful in a superconducting RF cavity, includes a housing for maintaining vacuum, a cathode, e.g., a photocathode, and the non-contaminating NEA secondary emitter with the uniform electrically conductive layer superposed thereon.

  2. Simulations of Gaussian electron guns for RHIC electron lens

    Energy Technology Data Exchange (ETDEWEB)

    Pikin, A. [Brookhaven National Lab. (BNL), Upton, NY (United States). Collider-Accelerator Dept.

    2014-02-28

    Simulations of two versions of the electron gun for RHIC electron lens are presented. The electron guns have to generate an electron beam with Gaussian radial profile of the electron beam density. To achieve the Gaussian electron emission profile on the cathode we used a combination of the gun electrodes and shaping of the cathode surface. Dependence of electron gun performance parameters on the geometry of electrodes and the margins for electrodes positioning are presented.

  3. Dynamic Simulation of the Tank Gun Recoil Response

    Institute of Scientific and Technical Information of China (English)

    XING Jun-wen; WANG Liang-xi; SHI Yan; CHEN Chun-liang

    2005-01-01

    By using the ATV module of MSC. ADAMS, the dynamic simulation of recoil response of tank gun is analyzed.How the recoil force affects the bodywork and the suspension during gun firing, as well as the changing status of the gun muzzle's velocity are gained. All results and analyzing methods are offered for the designing basis of optimizing tank vehicle-gun match. The constructive exploration is beneficial to improving the general capability of tank.

  4. Improved DC Gun and Insulator Assembly

    Energy Technology Data Exchange (ETDEWEB)

    Neubauer, Michael [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States)

    2015-01-11

    Many user facilities such as synchrotron radiation light sources and free electron lasers rely on DC high voltage photoguns with internal field gradients as high as 10 to 15 MV/m. These high gradients often lead to field emission which poses serious problems for the photocathode used to generate the electron beam and the ceramic insulators used to bias the photocathode at high voltage. Ceramic insulators are difficult to manufacture, require long commissioning times, and have poor reliability, in part because energetic electrons bury themselves in the ceramic causing a buildup of charge and eventual puncture, and also because large diameter ceramics are difficult to braze reliably. The lifetimes of photo cathodes inside high current DC guns exhibiting field emission are limited to less than a hundred hours. Reducing the surface gradients on the metals reduces the field emission, which serves to maintain the required ultrahigh vacuum condition. A novel gun design with gradients around 5 MV/m and operating at 350 kV, a major improvement over existing designs, was proposed that allows for the in-situ replacement of photo cathodes in axially symmetric designs using inverted ceramics. In this project, the existing JLAB CEBAF asymmetric gun design with an inverted ceramic support was modeled and the beam dynamics characterized. An improved structure was designed that reduces the surface gradients and improves the beam optics. To minimize the surface gradients, a number of electrostatic gun designs were studied to determine the optimum configuration of the critical electrodes within the gun structure. Coating experiments were carried out to create a charge dissipative coating for cylindrical ceramics. The phase II proposal, which was not granted, included the design and fabrication of an axially symmetric DC Gun with an inverted ceramic that would operate with less than 5 MV/m at 350 kV and would be designed with an in-situ replaceable photo-cathode.

  5. Guns N’ Arenas黑枪事件

    Institute of Scientific and Technical Information of China (English)

    狄艾

    2010-01-01

    奇才队"零号探员"阿里纳斯(Gilbert Arenas)和知名摇滚乐团"枪和玫瑰(Guns N’Roses)"同样发迹于美国加州,但当"枪和阿里纳斯(Guns N’Are nas)"连结在一起时,代志就大条了!先前名气直逼摇滚巨星的阿里纳斯,恐怕将因去年12月的"黑枪事件"身败名裂!

  6. OCULAR INJURIES CAUSED BY BB GUN

    Directory of Open Access Journals (Sweden)

    M.S. Farahvash

    1999-08-01

    Full Text Available in ordere to determine the prognosis of perforating eye injuries caused hy BB guns in our patients, the"nvisual and anatomic results of 14 patients with gun injuries seen between September 1996 and February 1998 in Farafti Hospital and private office in Tehran were reviewed. Five patients liad nonn erf orating eye injuries. All perforated eyes underwent scleral buckling, tenseclomy, vitrectomy ami silicone injection. All injured iyes had a visual acuity of light perception or better at presentation. Among 9 cases of perforating injuries. 7 had doable and 2 had single perforation. All patients had a final.

  7. 78 FR 11902 - Review of Gun Safety Technologies

    Science.gov (United States)

    2013-02-20

    ... of Justice Programs Review of Gun Safety Technologies AGENCY: National Institute of Justice, JPO, DOJ...) is conducting a review of existing and emerging gun safety technologies and plans to issue a report... to help inform its technology assessment and market research of existing and emerging gun...

  8. Gun Violence and Children: Factors Related To Exposure and Trauma.

    Science.gov (United States)

    Slovak, Karen

    2002-01-01

    Study investigated relationship between access to firearms and parental monitoring on rural youths' exposure to gun violence, and examined the effect of gun violence exposure on mental health. Results indicated a substantial number were exposed to gun violence. Exposure was related to firearm access and parental monitoring. Implications for social…

  9. Frequency of Guns in the Households of High School Seniors

    Science.gov (United States)

    Coker, Ann L.; Bush, Heather M.; Follingstad, Diane R.; Brancato, Candace J.

    2017-01-01

    Background: In 2013, President Obama lifted the federal ban on gun violence research. The current study provides one of the first reports to estimate household gun ownership as reported by youth. Methods: In this cohort study of 3,006 high school seniors from 24 schools, we examined the frequency of household guns ownership. Results: About 65%…

  10. Should Gun Safety Be Taught in Schools? Perspectives of Teachers

    Science.gov (United States)

    Obeng, Cecilia

    2010-01-01

    Background: Gun-related injuries and deaths among children occur at disproportionately high rates in the United States. Children who live in homes with guns are the most likely victims. This study describes teachers' views on whether gun safety should be taught to children in the preschool and elementary years. Methods: A total of 150 survey…

  11. Frequency of Guns in the Households of High School Seniors

    Science.gov (United States)

    Coker, Ann L.; Bush, Heather M.; Follingstad, Diane R.; Brancato, Candace J.

    2017-01-01

    Background: In 2013, President Obama lifted the federal ban on gun violence research. The current study provides one of the first reports to estimate household gun ownership as reported by youth. Methods: In this cohort study of 3,006 high school seniors from 24 schools, we examined the frequency of household guns ownership. Results: About 65%…

  12. Should Gun Safety Be Taught in Schools? Perspectives of Teachers

    Science.gov (United States)

    Obeng, Cecilia

    2010-01-01

    Background: Gun-related injuries and deaths among children occur at disproportionately high rates in the United States. Children who live in homes with guns are the most likely victims. This study describes teachers' views on whether gun safety should be taught to children in the preschool and elementary years. Methods: A total of 150 survey…

  13. Study of Control Grid Thermionic Cathode RF Gun

    CERN Document Server

    Xiao, Jin; Ming, Li; Xinfan, Yang; Xumin, Shen; Yanan, Chen; Zhou, Xu

    2004-01-01

    In this paper, the beam loading effect of RF Gun was analyzed. To minimize the energy spread, the grid control RF Gun was introduced. The result shows that the grid congrol RF Gun can increase electron beam within 1% energy spread.

  14. Demand Analysis of Informational Shipboard Gun Weapon System Interface Design

    Directory of Open Access Journals (Sweden)

    WANG Hui-chuan

    2013-04-01

    Full Text Available According to development demand of informational shipboard gun weapon system, design concept of shipboard gun weapon system interface is proposed. System composition is put forward and function demand of interface is analyzed from combat, training and detection aspects. General principle need to be followed in design process. A new concept is provided for development of shipboard gun weapon system interface.

  15. Fired Models of Air-gun Source and Its Application

    Institute of Scientific and Technical Information of China (English)

    Luo Guichun; Ge Hongkui; Wang Baoshan; Hu Ping; Mu Hongwang; Chen Yong

    2008-01-01

    Air-gun is an important active seismic source. With the development of the theory about air-gun array, the technique for air-gun array design becomes mature and is widely used in petroleum exploration and geophysics. In order to adapt it to different research domains,different combination and fired models are needed. At the present time, there are two firedmodels of air-gun source, namely, reinforced initial pulse and reinforced first bubble pulse.The fired time, space between single guns, frequency and resolution of the two models are different. This comparison can supply the basis for its extensive application.

  16. Performance of a carbon nanotube field emission electron gun

    Science.gov (United States)

    Getty, Stephanie A.; King, Todd T.; Bis, Rachael A.; Jones, Hollis H.; Herrero, Federico; Lynch, Bernard A.; Roman, Patrick; Mahaffy, Paul

    2007-04-01

    A cold cathode field emission electron gun (e-gun) based on a patterned carbon nanotube (CNT) film has been fabricated for use in a miniaturized reflectron time-of-flight mass spectrometer (RTOF MS), with future applications in other charged particle spectrometers, and performance of the CNT e-gun has been evaluated. A thermionic electron gun has also been fabricated and evaluated in parallel and its performance is used as a benchmark in the evaluation of our CNT e-gun. Implications for future improvements and integration into the RTOF MS are discussed.

  17. Grip-Pattern Recognition for Smart Guns

    NARCIS (Netherlands)

    Kauffman, J.A.; Bazen, A.M.; Gerez, S.H.; Veldhuis, R.N.J.

    2003-01-01

    This paper describes the design, implementation and evaluation of a user-verification system for a smart gun, which is based on grip-pattern recognition. An existing pressure sensor consisting of an array of 44 x 44 piezoresistive elements has been used. An interface has been developed to acquire pr

  18. RF Gun Photocathode Research at SLAC

    Energy Technology Data Exchange (ETDEWEB)

    Jongewaard, E.; Akre, R.; Brachmann, A.; Corbett, J.; Gilevich, S.; Grouev, K.; Hering, P.; P.Krejcik,; Lewandowski, J.; Loos, H.; Montagne, T.; Sheppard, J.C.; Stefan, P.; Vlieks, A.; Weathersby, S.; Zhou, F.; /SLAC

    2012-05-16

    LCLS is presently operating with a third copper photocathode in the original rf gun, with a quantum efficiency (QE) of {approx}1 x 10{sup -4} and projected emittance {gamma}{var_epsilon}{sub x,y} = 0.45 {micro}m at 250 pC bunch charge. The spare LCLS gun is installed in the SLAC Accelerator Structure Test Area (ASTA), fully processed to high rf power. As part of a wider photocathode R and D program, a UV laser system and additional gun diagnostics are being installed at ASTA to measure QE, QE lifetime, and electron beam emittance under a variety of operating conditions. The near-term goals are to test and verify the spare photocathode production/installation sequence, including transfer from the final holding chamber to the rf gun. Mid- and longer-term goals include development of a rigorous understanding of plasma and laser-assisted surface conditioning and investigation of new, high-QE photocathode materials. In parallel, an x-ray photoemission spectroscopy station is nearing completion, to analyze Cu photocathode surface chemistry. In this paper we review the status and anticipated operating parameters of ASTA and the spectroscopy test chamber.

  19. College Students Opinions on Gun Violence.

    Science.gov (United States)

    Lewis, Rhonda K; LoCurto, Jamie; Brown, Kyrah; Stowell, David; Maryman, J'Vonnah; Dean, Amber; McNair, Thoi; Ojeda, Debbie; Siwierka, Julia

    2016-06-01

    Gun violence and control issues have become serious public health problems. This study gathered the opinions from 419 college students from a Midwestern University. Participants were asked about beliefs about purchasing assault weapons, beliefs about bringing handguns to college campuses and beliefs about contributing factors that lead to gun violence. Participants completed surveys online. The findings showed that overall 54 % of respondents believed that military assault weapons should be banned and 53 % agree that teachers should be allowed to carry a registered handgun on campus. There were statistically significant differences between males and females on these issues. For instance, females believed military assault weapons and high capacity magazines should be banned more than 1.9 times (p = .004) p gun violence were decline in parenting and family values (17 %), gang involvement (14 %), bullying (13.8 %) and guns being easy to obtain (13.8 %). Limitations and implications for policy work are discussed.

  20. Green plasticizers for multibase gun propellants (Lecture)

    NARCIS (Netherlands)

    Schoolderman, C.; Driel, C.A. van; Zebregs, M.

    2007-01-01

    TNO Defence, Security and Safety has a long history of research on gun propellants. Areas investigated are formulating (new ingredients, optimization), manufacturing, charge design and lifetime assessment [1,2,3,4,5]. In conventional propellants inert plasticizers are used to alter performance,

  1. Gas powered fluid gun with recoil mitigation

    Energy Technology Data Exchange (ETDEWEB)

    Grubelich, Mark C.; Yonas, Gerold

    2017-01-03

    A gas powered fluid gun for propelling a stream or slug of a fluid at high velocity toward a target. Recoil mitigation is provided by a cavitating venturi that reduces or eliminates the associated recoil forces, with minimal or no backwash. By launching a quantity of water in the opposite direction, net momentum forces are reduced or eliminated.

  2. Microwave electron gun theory and experiments

    Science.gov (United States)

    Gao, J.

    1992-01-01

    A general microwave electron gun (rf gun) theory and some new ideas about further reducing the emittance of electron beams are reviewed and introduced briefly. Experimental results are presented from a thermionic cathode rf gun which has been developed for Beijing Free-Electron Laser Project (BFELP) at Institute of High Energy Physics (IHEP), Academia Sinica as the injector of 30 MeV constant gradient linac. LaB6 is used as the thermionic emitter with 100 crystal surface and the temperature around 1620 °C. Back bombardment heating effect and another effect connected with the cathode surface temperature was observed. An electron beam with macropulse length 4 μs, repetition rate 12.5 Hz, greater than 500 mA beam current during macropulse and around 1 MeV maximum energy has been obtained. In the last section of this article, two useful formulas used to determine electric field distribution near the cathode surface and coupling coefficient β of a rf gun are introduced.

  3. Guns on Campus: A Chilling Effect

    Science.gov (United States)

    Mash, Kenneth M.

    2013-01-01

    The author of this article observes that, while much has been written on the overall topic of safety with regard to allowing guns on college campuses, little has been said about how allowing the possession of deadly weapons can create a "chilling effect" on academic discussions. This article considers how some universities have…

  4. Factors affecting penetrating captive bolt gun performance.

    Science.gov (United States)

    Gibson, Troy J; Mason, Charles W; Spence, Jade Y; Barker, Heather; Gregory, Neville G

    2015-01-01

    Captive bolt stunning is used for rendering livestock insensible at slaughter. The mechanical factors relating to performance of 6 penetrating captive bolt gun (CBG) models were examined. The Matador Super Sécurit 3000 and the .25 Cash Euro Stunner had the highest kinetic energy values (443 J and 412 J, respectively) of the CBGs tested. Ninety percent (27/30) of CBGs held at a government gun repository (United Kingdom) were found to have performed at a normal standard for the model, while 53% (10/19) of commercial contractor CBGs tested were found to underperform for the gun model. When the .22 Cash Special was fired 500 times at 4 shots per min, the gun reached a peak temperature of 88.8°C after 2.05 hr. Repeat firing during extended periods significantly reduced the performance of the CBG. When deciding on the appropriate CBG/cartridge combination, the kinetic energy delivered to the head of the nonhuman animal, bolt penetration depth, and species/animal type must be considered. It is recommended that CBGs are routinely checked for wear to the bolt and barrel if they are repeatedly fired in a session.

  5. Magnetic guns with cylindrical permanent magnets

    DEFF Research Database (Denmark)

    Vokoun, David; Beleggia, Marco; Heller, Luděk

    2012-01-01

    The motion of a cylindrical permanent magnet (projectile) inside a tubular permanent magnet, with both magnets magnetized axially, illustrates nicely the physical principles behind the operation of magnetic guns. The force acting upon the projectile is expressed semi-analytically as derivative...

  6. Issue Management and the Australian Gun Debate.

    Science.gov (United States)

    Reynolds, Christopher

    1997-01-01

    Examines the rise and fall of media coverage of the issues of gun control and political conflict in Australia after an incident of mass murder in April 1996. Aims to reveal the issue management process that occurred and the hidden agendas that motivated the political and media activity. Demonstrates the media's role in the creation of issue…

  7. Green plasticizers for multibase gun propellants (Lecture)

    NARCIS (Netherlands)

    Schoolderman, C.; Driel, C.A. van; Zebregs, M.

    2007-01-01

    TNO Defence, Security and Safety has a long history of research on gun propellants. Areas investigated are formulating (new ingredients, optimization), manufacturing, charge design and lifetime assessment [1,2,3,4,5]. In conventional propellants inert plasticizers are used to alter performance, proc

  8. Guns on Campus: A Chilling Effect

    Science.gov (United States)

    Mash, Kenneth M.

    2013-01-01

    The author of this article observes that, while much has been written on the overall topic of safety with regard to allowing guns on college campuses, little has been said about how allowing the possession of deadly weapons can create a "chilling effect" on academic discussions. This article considers how some universities have…

  9. Nerf Guns Strike a Nerve on Campuses

    Science.gov (United States)

    Young, Jeffrey R.

    2008-01-01

    Killing zombies on campus just isn't as much fun as it used to be. Students at Bowling Green State University once carried Nerf guns for a week each semester, shooting the zombies before the creatures could tag them. Participants were seen by most bystanders as nerdy but harmless kids who liked role-playing. These days, bright plastic Nerf guns…

  10. Cerebral damage caused by nail gun injury

    Directory of Open Access Journals (Sweden)

    Andersen Chris Hedeman

    2016-06-01

    Full Text Available Background Accidents with nail guns are rather common, especially in the construction industry. Most injuries involve the extremities and several present with intracerebral injuries. When the patient is unconscious, it can be a big challenge to determine whether the injury is an accident, self-inflicted or a criminal act.

  11. Safety Plan for Schools: No Guns

    Science.gov (United States)

    Shah, Nirvi

    2013-01-01

    In a pre-emptive move against a school safety proposal from the National Rifle Association that is expected to include a call for more people trained and approved to carry guns at schools, a coalition of civil rights and education groups unveiled its own safety plan last week. It seeks the creation of positive school climates, thoughtful and…

  12. Toward a terahertz-driven electron gun

    Science.gov (United States)

    Huang, W. Ronny; Nanni, Emilio A.; Ravi, Koustuban; Hong, Kyung-Han; Fallahi, Arya; Wong, Liang Jie; Keathley, Phillip D.; Zapata, Luis E.; Kärtner, Franz X.

    2015-01-01

    Femtosecond electron bunches with keV energies and eV energy spread are needed by condensed matter physicists to resolve state transitions in carbon nanotubes, molecular structures, organic salts, and charge density wave materials. These semirelativistic electron sources are not only of interest for ultrafast electron diffraction, but also for electron energy-loss spectroscopy and as a seed for x-ray FELs. Thus far, the output energy spread (hence pulse duration) of ultrafast electron guns has been limited by the achievable electric field at the surface of the emitter, which is 10 MV/m for DC guns and 200 MV/m for RF guns. A single-cycle THz electron gun provides a unique opportunity to not only achieve GV/m surface electric fields but also with relatively low THz pulse energies, since a single-cycle transform-limited waveform is the most efficient way to achieve intense electric fields. Here, electron bunches of 50 fC from a flat copper photocathode are accelerated from rest to tens of eV by a microjoule THz pulse with peak electric field of 72 MV/m at 1 kHz repetition rate. We show that scaling to the readily-available GV/m THz field regime would translate to monoenergetic electron beams of ~100 keV. PMID:26486697

  13. How Sociology Texts Address Gun Control

    Science.gov (United States)

    Tonso, William R.

    2004-01-01

    William R. Tonso has chosen an issue that he knows something about to examine how sociology textbooks address controversy. Appealing for gun control is fashionable, but it is at odds with a fondness that ordinary Americans have for their firearms--one that is supported by a growing body of research on deterrence to crime. There are two sides to…

  14. Capital Punishment, Gun Ownership, and Homicide.

    Science.gov (United States)

    Kleck, Gary

    1979-01-01

    Examines two controversial questions related to the problem of interpersonal violence in America: (1) Does use of the death penalty exert any measurable influence on the rate of homicide in the United States? (2) What relationship, if any, exists between the level of gun ownership and the level of homicide violence? (Author)

  15. Discussion on the Improvement of Security Functions of Railway Communication by the Hand-held Mobile Monitoring Positioning Terminal%手持移动监控定位终端改进铁路通信安全功能探讨

    Institute of Scientific and Technical Information of China (English)

    杨青

    2015-01-01

    Through analyzing the existing problems of the monitoring and command of the original railway communication work, this paper expounds the functions of hand-held mobile monitoring positioning terminal to show that the application of monitor terminal system in railway communication system plays an important role in improving the emergency rescue of railway communication and the control of construction work and protecting the operation security of railway communication. The application of terminal greatly improves the working accuracy, shortens the time of failure treatment, reduces the economic losses caused by the faults and greatly improves the efficiency of railway communication. It is helpful to achieve the goal of value management.%本文通过分析原有铁路通信作业监控指挥存在的问题,阐述手持移动监控定位终端的功能,进而说明在铁路通信系统中应用监控终端系统,在改进铁路通信应急抢险和施工作业把控及铁路通信作业安全保障方面发挥的重要作用。终端的使用大大提高了作业精度,缩短了处理故障的时间,降低了故障造成的经济损失,从而大大提高铁路通信的效率,有助于实现价值管理的目标。

  16. Gun utopias? Firearm access and ownership in Israel and Switzerland.

    Science.gov (United States)

    Rosenbaum, Janet E

    2012-02-01

    The 2011 attempted assassination of a US representative renewed the national gun control debate. Gun advocates claim mass-casualty events are mitigated and deterred with three policies: (a) permissive gun laws, (b) widespread gun ownership, (c) and encouragement of armed civilians who can intercept shooters. They cite Switzerland and Israel as exemplars. We evaluate these claims with analysis of International Crime Victimization Survey (ICVS) data and translation of laws and original source material. Swiss and Israeli laws limit firearm ownership and require permit renewal one to four times annually. ICVS analysis finds the United States has more firearms per capita and per household than either country. Switzerland and Israel curtail off-duty soldiers' firearm access to prevent firearm deaths. Suicide among soldiers decreased by 40 per cent after the Israeli army's 2006 reforms. Compared with the United States, Switzerland and Israel have lower gun ownership and stricter gun laws, and their policies discourage personal gun ownership.

  17. 46 CFR 160.031-4 - Equipment for shoulder gun type line-throwing appliance.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 6 2010-10-01 2010-10-01 false Equipment for shoulder gun type line-throwing appliance... Appliance, Shoulder Gun Type (and Equipment) § 160.031-4 Equipment for shoulder gun type line-throwing... the gun. The line canister shall be secured by clamps or brackets below the barrel of the gun. (c) One...

  18. Gun possession among American youth: a discovery-based approach to understand gun violence.

    Science.gov (United States)

    Ruggles, Kelly V; Rajan, Sonali

    2014-01-01

    To apply discovery-based computational methods to nationally representative data from the Centers for Disease Control and Preventions' Youth Risk Behavior Surveillance System to better understand and visualize the behavioral factors associated with gun possession among adolescent youth. Our study uncovered the multidimensional nature of gun possession across nearly five million unique data points over a ten year period (2001-2011). Specifically, we automated odds ratio calculations for 55 risk behaviors to assemble a comprehensive table of associations for every behavior combination. Downstream analyses included the hierarchical clustering of risk behaviors based on their association "fingerprint" to 1) visualize and assess which behaviors frequently co-occur and 2) evaluate which risk behaviors are consistently found to be associated with gun possession. From these analyses, we identified more than 40 behavioral factors, including heroin use, using snuff on school property, having been injured in a fight, and having been a victim of sexual violence, that have and continue to be strongly associated with gun possession. Additionally, we identified six behavioral clusters based on association similarities: 1) physical activity and nutrition; 2) disordered eating, suicide and sexual violence; 3) weapon carrying and physical safety; 4) alcohol, marijuana and cigarette use; 5) drug use on school property and 6) overall drug use. Use of computational methodologies identified multiple risk behaviors, beyond more commonly discussed indicators of poor mental health, that are associated with gun possession among youth. Implications for prevention efforts and future interdisciplinary work applying computational methods to behavioral science data are described.

  19. Cerebral damage caused by nail gun injury

    DEFF Research Database (Denmark)

    Andersen, Chris

    2016-01-01

    . The forensic examination showed lesions of intracranial surgery and minor bruises on the arms. No sign of defense injuries was found. There were no signs of malfunction of the nail gun-wielding robot. On the side of the machine, there were a handheld nail gun and the police investigated the case as a possible......-inflicted or a criminal act. Case presentation A 43-year-old male worker was brought to the emergency department after his coworkers had found him on the floor in the cafeteria at work. He was admitted to the hospital due to a possible apoplexy. The CT scan revealed a nail in his skull and acute surgery was performed...

  20. Field Test Kit for Gun Residue Detection

    Energy Technology Data Exchange (ETDEWEB)

    WALKER, PAMELA K.; RODACY, PHILIP J.

    2002-01-01

    One of the major needs of the law enforcement field is a product that quickly, accurately, and inexpensively identifies whether a person has recently fired a gun--even if the suspect has attempted to wash the traces of gunpowder off. The Field Test Kit for Gunshot Residue Identification based on Sandia National Laboratories technology works with a wide variety of handguns and other weaponry using gunpowder. There are several organic chemicals in small arms propellants such as nitrocellulose, nitroglycerine, dinitrotoluene, and nitrites left behind after the firing of a gun that result from the incomplete combustion of the gunpowder. Sandia has developed a colorimetric shooter identification kit for in situ detection of gunshot residue (GSR) from a suspect. The test kit is the first of its kind and is small, inexpensive, and easily transported by individual law enforcement personnel requiring minimal training for effective use. It will provide immediate information identifying gunshot residue.

  1. Cerebral damage caused by nail gun injury

    DEFF Research Database (Denmark)

    Andersen, Chris

    2016-01-01

    . The forensic examination showed lesions of intracranial surgery and minor bruises on the arms. No sign of defense injuries was found. There were no signs of malfunction of the nail gun-wielding robot. On the side of the machine, there were a handheld nail gun and the police investigated the case as a possible......-inflicted or a criminal act. Case presentation A 43-year-old male worker was brought to the emergency department after his coworkers had found him on the floor in the cafeteria at work. He was admitted to the hospital due to a possible apoplexy. The CT scan revealed a nail in his skull and acute surgery was performed...

  2. Electrical parameters of projectile stun guns.

    Science.gov (United States)

    McDaniel, Wayne C; Benwell, Andrew; Kovaleski, Scott

    2009-01-01

    Projectile stun guns have been developed as less-lethal devices that law enforcement officers can use to control potentially violent subjects, as an alternative to using firearms. These devices apply high voltage, low amperage, pulsatile electric shocks to the subject, which causes involuntary skeletal muscle contraction and renders the subject unable to further resist. In field use of these devices, the electric shock is often applied to the thorax, which raises the issue of cardiac safety of these devices. An important determinant of the cardiac safety of these devices is their electrical output. Here the outputs of three commercially available projectile stun guns were evaluated with a resistive load and in a human-sized animal model (a 72 kg pig).

  3. High Impetus Cool Burning Gun Propellants

    Directory of Open Access Journals (Sweden)

    R.S. Dames

    2000-07-01

    Full Text Available This study explores the possibility of reducing the flame temperature (Tf without decrease in impetus of RDX-NC matrix-based high energy gun propellants by partial replacement of RDX with triaminoguanidine nitrate (TAGN. Compositions containing TAGN as an energetic oxidiser with varying percentage of RDX have been formulated. Glycidyl azide polymer was incorporated as an energetic plasticiser to achieve the higher level of impetus. Performance in terms of ballistic parameters (theoretical/experimental sensitivity, thermal characteristics, stability and mechanical properties was evaluated and compared with the basic composition containing RDX as a single oxidiser. Experimental data indicates that the partial replacement of RDX by TAGN in gun propellant compositions decreases Tf significantly with only marginal decrease in impetus. "

  4. Hall effect degradation of rail gun performance

    Science.gov (United States)

    Witalis, E. A.; Gunnarsson, Patrik

    1993-01-01

    The paper discusses the Hall effect and shows it to be significant in the low-density and high-field trailing part of a plasma armature. Without the Hall effect a simple armature model is derived. It exhibits properties expected from classical MHD theory and shows that the purely relativistic electric charge buildup on the rails is a fundamental gun property, leading to V(breech) = 1.5 V(muzzle). The mathematics involved in accounting for Hall effect phenomena is described. These are of two types: the Hall-skewing of the armature current and the superimposed plasma flow rotation. For decreasing gun current the two effects efficiently combine to eject armature plasma rearwards, thus creating conditions for arc separation and parasitic arcs.

  5. Statistics tolerances on built up guns.

    Directory of Open Access Journals (Sweden)

    J. P. Sirpal

    1962-07-01

    Full Text Available The strength of built up guns depends on the shrinkages allowed between cylinders and therefore for a given strength, the assembly is either selective or the nominal sizes are so chosen as to give the required shrinkage for a worst combination, it can be seen from the analysis that with little disadvantage tolerances can be greatly increased assuming random assemblies of parts whose sizes follow a normal pattern. This can bring down production costs considerably.

  6. Explosively Bonded Gun Tube Liner Development

    Science.gov (United States)

    2015-04-01

    level (MRL 10) measures aspects of lean practices and continuous improvement for systems in production. C.1 MRL 1: Basic Manufacturing Implications...the art is assessed through the use of Technology and Manufacturing Readiness Levels. 15. SUBJECT TERMS Ta alloys, gun-tube liners, explosive...bonding, firing tests, Technology Readiness Level, Manufacturing Readiness Level 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT UU 18

  7. Media violence, gun control, and public policy.

    Science.gov (United States)

    Zuckerman, D M

    1996-07-01

    Public concern with the national level of violence is discussed, and the complexity of the issue delineated. Research findings in two key areas of the topic, media violence and availability of firearms, are examined, as is their applicability to public policy efforts and recommendations for the prevention of violence. An approach that combines efforts to counteract media violence with those aimed at effective gun control is outlined in terms of bringing about changes in attitudes toward violence and firearm possession.

  8. Goods for Guns--the use of a gun buyback as an injury prevention/community education tool.

    Science.gov (United States)

    McGuire, Margaret; Manno, Mariann; Rook, Allison; Maranda, Louise; Renaud, Elizabeth; DeRoss, Anthony; Hirsh, Michael

    2011-11-01

    US children aged between 5 years and 14 years have a rate of gun-related homicide 17 times higher and a rate of gun-related suicide and unintentional firearm injury 10 times higher than other developed countries. Gun buyback programs have been criticized as ineffective interventions in decreasing violence. The Injury Free Coalition for Kids-Worcester (IFCK-W) Goods for Guns buyback is a multipronged approach to address these concerns and to reduce the number of firearms in the community. The IFCK-W buyback program is funded by corporate sponsors, grants, and individual donations. Citizens are instructed to transport guns, ammunition, and weapons safely to police headquarters on two Saturdays in December. Participants are guaranteed anonymity by the District Attorney's office and receive gift certificates for operable guns. Trained volunteers administer an anonymous survey to willing participants. Individuals who disclose having unsafely stored guns remaining at home receive educational counseling and trigger locks. Guns and ammunition are destroyed at a later time in a gun crushing ceremony. Since 2002, 1,861 guns (444 rifle/shotgun, 738 pistol/revolver, and 679 automatic/semiautomatic) have been collected at a cost of $99,250 (average, $53/gun). Seven hundred ten people have surrendered firearms, 534 surveys have been administered, and ≈ 75 trigger locks have been distributed per year. IFCK-W Goods for Guns is a relatively inexpensive injury prevention model program that removes unwanted firearms from homes, raises community awareness about gun safety, and provides high-risk individuals with trigger locks and educational counseling.

  9. The HART I augmented electric gun facility

    Energy Technology Data Exchange (ETDEWEB)

    Fikse, D.A.; Ciesar, J.A.; Wehrli, H.A.; Rimersma, H.; Docherty, E.F.; Pipich, C.W. (Westinghouse Science and Technology Center, Pittsburgh, PA (US))

    1991-01-01

    This paper reports on an augmented electric gun system that has been commissioned. This system, called HART I (Hypervelocity Augmented Railgun Test), is built around a double augmented rail arrangement with a 1.27-cm square bore. It is powered by the SUVAC II 5.6-MJ distributed capacitor power supply. This arrangement allows operation in a simple, series augmented, or transaugmented gun system configuration. The objective of this facility is to perform materials research augmentation studies, and armature development in the 10-km/s regime. Armature masses of 2 to 4 g will be accelerated in a 4-m long barrel. Baseline bore materials will begin with conventional G9/GlidCop systems and then move into pyrolytic boron nitride/refractory materials. Hybrids, plasma, and ablation stabilized armature systems are planned. The gun system is instrumented with plasma and rail B-dot probes for inbore velocity measurements. In addition, breech and muzzle voltages, currents, and external velocities are measured. The HART I system is currently performing hypervelocity experiments to verify the augmentation models.

  10. Diagnostics Beamline for the SRF Gun Project

    CERN Document Server

    Kamps, T; Goldammer, K; Krämer, Dietrich; Kuske, P; Kuszynski, J; Lipka, D; Marhauser, F; Quast, T; Richter, R

    2005-01-01

    A superconducting rf photo electron injector (SRF gun) is currently under construction by a collaboration between BESSY, DESY, FZR and MBI. The project aims at the design and setup of an CW SRF gun including a diagnostics beamline for the ELBE FEL and to address R&D issues on low emittance injectors for future light sources such as the BESSY FEL. Of critical importance for the injector performance is the control of the electron beam parameters. For this reason a compact diagnostics beamline is under development serving a multitude of operation settings ranging from low-charge (77pC), low-emittance (1 pi mm mrad) mode to high-charge (2.5nC) operation of the gun. For these operation modes beam dynamics simulations are resulting in boundary conditions for the beam instrumentation. Proven and mature technology is projected wherever possible, for example for current and beam position monitoring. The layout of the beam profile and emittance measurement systems is described. For the bunch length, which varies be...

  11. Microcracks repairing technique for gun barrel

    Institute of Scientific and Technical Information of China (English)

    YU Xu-dong; WU Bin; SU Bing; WANG Cheng-tao

    2004-01-01

    When a gun fires the diffusion of chemical species from the propellant gas, such as CO, CO2, H2, H2O and N2, into the hot surface through the microcracks forms reaction products and speeds up the erosion process.Therefore, crack repairing and healing can be a possible measure for protecting against erosion of gun bore. The present study develops a novel nanocomposite with the size of 30 - 150 nm to repair and heal the microcracks so that the propellant gas can be prevented from reacting with the steel. Sample of gun steel 40CrNiMoV plate (10 mm× 10 mm × 2 mm) is prepared and a fishtail crack is generated through a repeated plastic deformation process. The crackrepairing results show that the fishtail crack become shorter and narrower. A new phase is formed, which is found to have the elements, such as Ca, La, from the raw materials of nanocomposite by energy spectrum analysis.

  12. Diagnostics Beamline for the SRF Gun Project

    Energy Technology Data Exchange (ETDEWEB)

    T. Kamps; V. Durr; K. Goldammer; D. Kramer; P. Kuske; J. Kuszynski; D. Lipka; F. Marhauser; T. Quast; D. Richter; U. Lehnert; P. Michel; J. Teichert; P. Evtushenko; I. Will

    2005-08-22

    A superconducting radio-frequency photo electron injector (SRF gun) is currently under construction by a collaboration of BESSY, DESY, FZR and MBI. The project aims at the design and setup of a CW SRF gun including a diagnostics beamline for the ELBE FEL and to address R&D issues on low emittance injectors for future light sources such as the BESSY FEL. Of critical importance for the injector performance is the control of the electron beam parameters. For this reason a compact diagnostics beamline is under development serving a multitude of operation settings ranging from low-charge (77pC), low-emittance (1 mm mrad) mode to high-charge (2.5nC) operation of the gun. For these operation modes beam dynamics simulations are resulting in boundary conditions for the beam instrumentation. Proven and mature technology is projected wherever possible, for example for current and beam position monitoring. The layout of the beam profile and emittance measurement systems is described. For the bunch length, which varies between 5 ps and 50 ps, two schemes using electro-optical sampling and Cherenkov radiation are detailed. The beam energy and energy spread is measured with a 180-degree spectrometer.

  13. Beam-Based Procedures for RF Guns

    CERN Document Server

    Krasilnikov, Mikhail; Grabosch, H J; Hartrott, Michael; Hui Han, Jang; Miltchev, Velizar; Oppelt, Anne; Petrosyan, Bagrat; Staykov, Lazar; Stephan, Frank

    2005-01-01

    A wide range of rf photo injector parameters has to be optimized in order to achieve an electron source performance as required for linac based high gain FELs. Some of the machine parameters can not be precisely controlled by direct measurements, whereas the tolerance on them is extremely tight. Therefore, this should be met with beam-based techniques. Procedures for beam-based alignment (BBA) of the laser on the photo cathode as well as solenoid alignment have been developed. They were applied at the Photo Injector Test facility at DESY Zeuthen (PITZ) and at the photo injector of the VUV-FEL at DESY Hamburg. A field balance of the accelerating mode in the 1 ½ cell gun cavity is one of the key beam dynamics issues of the rf gun. Since no direct field measurement in the half and full cell of the cavity is available for the PITZ gun, a beam-based technique to determine the field balance has been proposed. A beam-based rf phase monitoring procedure has been developed as well.

  14. Overview of Plasma Guns for PLX

    Science.gov (United States)

    Witherspoon, F. Douglas; Bomgardner, Richard; Case, Andrew; Messer, Sarah; Brockington, Samuel; Wu, Linchun; Elton, Raymond; Hsu, Scott; Cassibry, Jason; Gilmore, Mark

    2010-11-01

    Plasma guns are being developed for use on the Plasma Liner Experiment (PLX) located at LANL. The collapsing plasma liner will be formed via merging of 30-60 dense, high Mach number plasma jets (n˜10^16-17 cm-3, M˜10--35, v˜50--70 km/s, rjet˜5 cm) in a spherically convergent geometry. Small parallel-plate railguns are being developed for this purpose. Each gun will operate at ˜300-600 kA peak current, and launch up to ˜8000 μg of high-Z plasma (Ar, Xe) using a ˜50 kJ pfn. We are now successfully operating with very fast gas valve injection of Ar, and have already achieved good performance of 1200 μg at 42 km/s, and 4000 μg at 20-25 km/s at low current. Work is underway to increase both the mass and velocity using higher current. We describe experimental development of the minirailguns and their present and projected performance. We also discuss options for modest size coaxial guns that might achieve the same performance and provide additional control of the plasmoid structure.

  15. Structural Optimization of Machine Gun Based on Dynamic Stability Concept

    Institute of Scientific and Technical Information of China (English)

    LI Yong-jian; WANG Rui-lin; ZHANG Ben-jun

    2008-01-01

    Improving the firing accuracy is a final goal of structural optimization of machine guns. The main factors which affect the dispersion accuracy of machine gun are analyzed. Based on the concept of dynamic stability, a structural optimization model is built up, and the sensitivity of dispersion accuracy to design variables is analyzed. The optimization results of a type of machine gun show that the method is valid, feasible, and can be used as a guide to the structural optimization of other automatic weapons.

  16. A projectile for a rectangular barreled rail gun

    OpenAIRE

    Juanche, Francisco M.

    1999-01-01

    The Physics Department at the Naval Postgraduate School is developing a concept to overcome the problems that keep present rail guns from being practical weapons. The rails must be replaced often if the rail gun operation is to be continuous. Replacing the rails in present rail gun configurations is time consuming. The Physics Department's design concept uses a rectangular barrel as part of the solution to the problem of replacing the rails. The projectile will require flat surfaces to mainta...

  17. Pneumatic capillary gun for ballistic delivery of microparticles

    CERN Document Server

    Rinberg, D; Groisman, A; Rinberg, Dmitry; Simonnet, Claire; Groisman, Alex

    2005-01-01

    A pneumatic gun for ballistic delivery of microparticles to soft targets is proposed and demonstrated. The particles are accelerated by a high speed flow of Helium in a capillary tube. Vacuum suction applied to a concentric, larger diameter tube is used to completely divert the flow of Helium from the gun nozzle and prevent it from hitting the target. Depths of penetration of micron-sized gold particles into agarose gels and their speeds of ejection from the gun nozzle are measured.

  18. A flow cryostat for cooling of eight independent pipe guns

    DEFF Research Database (Denmark)

    Sørensen, H.; Hansen, J.E.; Sass, B.

    1991-01-01

    A flow cryostat allowing independent cooling of eight pipe guns in a multishot deuterium pellet injector is described. The pipe guns are placed symmetrically around the flow cryostat and with a liquid helium consumption of 4-5 l/h the cooling is sufficient for simultaneous formation of eight...... pellets at 8-9 K with a diameter of 2.1 mm containing up to 8 x 10(20) atoms/pellet. The thermal interaction between the eight pipe guns is sufficiently low to allow successive firing of the guns with time intervals of up to 1 s....

  19. Low Emittance Guns for the ILC Polarized Electron Beam

    Science.gov (United States)

    Clendenin, J. E.; Brachmann, A.; Ioakeimidi, K.; Kirby, R. E.; Maruyama, T.; Miller, R. H.; Wang, J. W.; Zhou, F.

    2007-06-01

    Polarized electron beams generated by DC guns are routinely available at several accelerators including JLAB, Mainz and SLAC. These guns operate with a cathode bias on the order of -100 kV. To minimize space charge effects, relatively long bunches are generated at the gun and then compressed longitudinally external to the gun just before and during initial acceleration. For linear colliders, this compression is accomplished using a combination of rf bunchers. For the basic design of the International Linear Collider (ILC), a 120 kV DC photocathode gun is used to produce a series of nanosecond bunches that are each compressed by two sub-harmonic bunchers (SHBs) followed by an L-band buncher and capture section. The longitudinal bunching process results in a significantly higher emittance than produced by the gun alone. While high-energy experiments using polarized beams are not generally sensitive to the source emittance, there are several benefits to a lower source emittance including a simpler more efficient injector system and a lower radiation load during transport especially at bends as at the damping ring. For the ILC, the SHBs could be eliminated if the voltage of the gun is raised sufficiently. Simulations using the General Particle Tracer (GPT) package indicate that a cathode bias voltage of ⩾200 kV should allow both SHBs to be operated at 433 or even 650 MHz, while ⩾500 kV would be required to eliminate the SHBs altogether. Simulations can be used to determine the minimum emittance possible if the injector is designed for a given increased voltage. A possible alternative to the DC gun is an rf gun. Emittance compensation, routinely used with rf guns, is discussed for higher-voltage DC guns.

  20. Action Alters Object Identification: Wielding a Gun Increases the Bias to See Guns

    Science.gov (United States)

    Witt, Jessica K.; Brockmole, James R.

    2012-01-01

    Stereotypes, expectations, and emotions influence an observer's ability to detect and categorize objects as guns. In light of recent work in action-perception interactions, however, there is another unexplored factor that may be critical: The action choices available to the perceiver. In five experiments, participants determined whether another…

  1. Perancangan Sistem Kontrol PID Untuk Pengendali Sumbu Elevasi Gun Pada Turret-Gun Kaliber 20 Milimeter

    Directory of Open Access Journals (Sweden)

    Dimas Kunto Ariwibowo

    2017-01-01

    Full Text Available Pertahanan negara pada hakikatnya adalah segala upaya pertahanan yang bersifat semesta yang didasarkan pada kesadaran atas hak dan kewajiban warga negara serta keyakinan pada kekuatan sendiri dengan tujuan untuk menjaga dan melindungi kedaulatan negara, keutuhan wilayah NKRI dan keselamatan segenap bangsa. Salah satu alat pendukung pertahanan yaitu senjata laras panjang, Turret-Gun.  Adapun langkah-langkah yang dilakukan dalam merancang pengendali PID Turret-Gun kaliber 20mm ini diawali dengan studi literatur serta studi lapangan mengenai mekanisme dan parameter-parameter yang terdapat pada Turret-Gun pada sumbu elevasi. Setelah itu dilakukan perancangan transmisi dan sistem kontrol Turret-Gun untuk dievaluasi grafik responnya yang akan digunakan sebagai acuan untuk merancang pengendali PID yang sesuai. Selanjutnya pengendali PID yang telah dirancang lalu disimulasikan, sehingga menghasilkan grafik respon yang sesuai dengan kriteria yang dibutuhkan. Hasil yang telah didapatkan dari penelitian ini adalah konstanta PID yang direkomendasikan untuk , , dan secara berturut-turut adalah sebesar 23061.024, 37820.07 dan 3515.4 yang menghasilkan transient response dengan nilai overshoot sebesar 19.9 % , steady state error sebesar 0 % serta settling time sebesar 0.935 detik. Hasil analisa kestabilan untuk sistem kontrol dengan konstanta PID tersebut menunjukkan bahwa sistem kontrol telah stabil, baik menggunakan metode Root Locus maupun metode Routh-Hurwitz.

  2. Action Alters Object Identification: Wielding a Gun Increases the Bias to See Guns

    Science.gov (United States)

    Witt, Jessica K.; Brockmole, James R.

    2012-01-01

    Stereotypes, expectations, and emotions influence an observer's ability to detect and categorize objects as guns. In light of recent work in action-perception interactions, however, there is another unexplored factor that may be critical: The action choices available to the perceiver. In five experiments, participants determined whether another…

  3. Cyclic Gun--Human Evolution: Soldiers, Guns, Machine Logic, and the Future

    Science.gov (United States)

    Blackmore, Tim

    2006-01-01

    Guns, slug-throwing weapons, have evolved as humans have increased their grasp of the mechanical arts. In the near future, however, it seems likely that soldiers' rifles operating at punishing cyclic rates of fire face the limits of physics and materials science--heat and speed will cost accuracy and distance. This article considers not only the…

  4. Gun buyback programs: a venue to eliminate unwanted guns in the community.

    Science.gov (United States)

    Violano, Pina; Driscoll, Cassandra; Chaudhary, Neil K; Schuster, Kevin M; Davis, Kimberly A; Borer, Esther; Winters, Jane K; Hirsh, Michael P

    2014-09-01

    The United States has a high rate of death due to firearms, and gun buyback programs may mitigate these high death rates. Understanding the demographics, motivation, and geographic region of participants may improve program efficacy. Three Injury Free Coalition for Kids gun buyback programs, in collaboration with the local police, were studied: Phoenix, Arizona; Worcester, Massachusetts; and New Haven, Connecticut. Participants were defined as those who relinquished a firearm. A self-administered, anonymous, paper survey elicited information from participants regarding demographic data, formal training on the use of the firearm, how the firearm was acquired, potential child access, knowledge of others injured by a firearm, whether the firearm was stored unlocked, factors motivating the surrender of the firearm, and other factors. Survey results were entered into a composite database and analyzed for differences in location, race, sex, and other factors. Participants (n = 301) were predominantly male (73.5%), white (80.9%), and older than 55 years (59.0%). They lived an average of 19.0 miles from the event by zip codes and had an average median household income of $65,731. More than half (54.5%) did not purchase the firearm, acquiring it through inheritance, gift, or random find. Most (74.8%) had previous firearms training and were relinquishing for safety reasons (68.3%). Those relinquishing firearms for safety reasons were less likely to have purchased the firearm (odds ratio [OR], 2.46, p gun lock (OR, 0.15; p gun-wielding criminal acts were burglarized from the home of legal gun owners that had failed to secure them properly. The gun buyback program is solely one prong of a multipronged approach in reducing firearm-based interpersonal violence. Additional research is necessary to determine effective methods to target individuals who would have the greatest impact on gun violence if they relinquished their weapons. Through the forging of relationships and

  5. Smart gun technology requirements preliminary report

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, D.R.; Brandt, D.J.; Tweet, K.D.

    1995-05-01

    Goal of the Smart Gun Technology project is to eliminate the capability of an unauthorized user from firing a law enforcement officer`s firearm by implementing user-recognizing-and-authorizing surety technologies. This project is funded by the National Institute of Justice. This document reports the projects first objective: to find and document the requirements for a user-recognizing-and-authorizing firearm technology that law enforcement officers will value. This report details the problem of firearm takeaways in law enforcement, the methodology used to develop the law enforcement officers` requirements, and the requirements themselves.

  6. Gas powered fluid gun with recoil mitigation

    Science.gov (United States)

    Grubelich, Mark C; Yonas, Gerold

    2013-11-12

    A gas powered fluid gun for propelling a stream or slug of a fluid at high velocity toward a target. Recoil mitigation is provided that reduces or eliminates the associated recoil forces, with minimal or no backwash. By launching a quantity of water in the opposite direction, net momentum forces are reduced or eliminated. Examples of recoil mitigation devices include a cone for making a conical fluid sheet, a device forming multiple impinging streams of fluid, a cavitating venturi, one or more spinning vanes, or an annular tangential entry/exit.

  7. Gas powered fluid gun with recoil mitigation

    Science.gov (United States)

    Grubelich, Mark C.; Yonas, Gerold

    2016-03-01

    A gas powered fluid gun for propelling a stream or slug of a fluid at high velocity toward a target. Recoil mitigation is provided that reduces or eliminates the associated recoil forces, with minimal or no backwash. By launching a quantity of water in the opposite direction, net momentum forces are reduced or eliminated. Examples of recoil mitigation devices include a cone for making a conical fluid sheet, a device forming multiple impinging streams of fluid, a cavitating venturi, one or more spinning vanes, or an annular tangential entry/exit.

  8. Characterisation of plasma in a rail gun

    Science.gov (United States)

    Ray, P. K.

    1986-01-01

    The mechanism of plasma and projectile acceleration in a DC rail gun is described from a microscopic point of view through the establishment of the Hall field. The plasma conductivity is shown to be a tensor, indicating that there is a small component of current parallel to the direction of acceleration. The plasma characteristics are evaluated in the experiment of Bauer et. al., as a function of plasma mass through a simple fluid mechanical analysis of the plasma. By equating the energy dissipatated in the plasma with the radiation heat loss, the properties of the plasma are determined.

  9. Electromagnetic Gun Circuit Analysis Code (EGCAC)

    Science.gov (United States)

    Rolader, Glenn E.; Thornhill, Lindsey D.; Batteh, Jad H.; Scanlon, James J., III

    1993-01-01

    This paper describes a system engineering code that simulates the performance of a railgun/power supply system. The code, named EGCAC (Electromagnetic Gun Circuit Analysis Code), accounts for many performance degrading effects including viscous drag on the armature, viscous drag on the gas being pushed in front of the projectile, entrained gas that must be accelerated in front of the projectile, time-dependent rail resistance, armature resistance, system resistance, and ablation drag. EGCAC has been utilized to predict railgun performance up to a velocity of approximately 4 km/s for experiments at several laboratories. In this paper, the theory of EGCAC is described, and sample calculations are presented.

  10. Gun possession among American youth: a discovery-based approach to understand gun violence.

    Directory of Open Access Journals (Sweden)

    Kelly V Ruggles

    Full Text Available OBJECTIVE: To apply discovery-based computational methods to nationally representative data from the Centers for Disease Control and Preventions' Youth Risk Behavior Surveillance System to better understand and visualize the behavioral factors associated with gun possession among adolescent youth. RESULTS: Our study uncovered the multidimensional nature of gun possession across nearly five million unique data points over a ten year period (2001-2011. Specifically, we automated odds ratio calculations for 55 risk behaviors to assemble a comprehensive table of associations for every behavior combination. Downstream analyses included the hierarchical clustering of risk behaviors based on their association "fingerprint" to 1 visualize and assess which behaviors frequently co-occur and 2 evaluate which risk behaviors are consistently found to be associated with gun possession. From these analyses, we identified more than 40 behavioral factors, including heroin use, using snuff on school property, having been injured in a fight, and having been a victim of sexual violence, that have and continue to be strongly associated with gun possession. Additionally, we identified six behavioral clusters based on association similarities: 1 physical activity and nutrition; 2 disordered eating, suicide and sexual violence; 3 weapon carrying and physical safety; 4 alcohol, marijuana and cigarette use; 5 drug use on school property and 6 overall drug use. CONCLUSIONS: Use of computational methodologies identified multiple risk behaviors, beyond more commonly discussed indicators of poor mental health, that are associated with gun possession among youth. Implications for prevention efforts and future interdisciplinary work applying computational methods to behavioral science data are described.

  11. Guns and Fear: A One-Way Street?

    Science.gov (United States)

    Hauser, Will; Kleck, Gary

    2013-01-01

    Surveys show that more than one half of gun owners report owning their firearm for self-protection. Although research has examined the effect of fear of crime on gun ownership, the issue of reciprocity and temporal order has been largely ignored. Furthermore, the effect of firearm acquisition and relinquishment on fear has not been evaluated…

  12. Preventing Clogging In A Vacuum Plasma Spray Gun

    Science.gov (United States)

    Krotz, Phillip D.; Daniel, Ronald L., Jr.; Davis, William M.

    1994-01-01

    Modification of powder-injection ports enables lengthy, high-temperature deposition operations. Graphite inserts prevent clogging of ports through which copper powder injected into vacuum plasma spray (VPS) gun. Graphite liners eliminate need to spend production time refurbishing VPS gun, reducing cost of production and increasing productivity. Concept also applied to other material systems used for net-shape fabrication via VPS.

  13. Everyday Engineering: What Makes a Squirt Gun Squirt?

    Science.gov (United States)

    Moyer, Richard; Everett, Susan

    2009-01-01

    You may not think of engineering and squirt guns in the same sentence. However, like many examples of engineering design, the squirt gun pump mechanism is uncomplicated, yet elegant, and very inexpensive to manufacture. The design is widely used because of its simplicity and low cost. With only a few moving parts, it is able to deliver a stream of…

  14. Normative Considerations in the Aftermath of Gun Violence in Schools

    Science.gov (United States)

    Gereluk, Dianne T.; Donlevy, J. Kent; Thompson, Merlin B.

    2015-01-01

    Gun violence in American and Canadian schools is an ongoing tragedy that goes substantially beyond its roots in the interlocking emotional and behavioral issues of mental health and bullying. In light of the need for effective policy development, Dianne T. Gereluk, J. Kent Donlevy, and Merlin B. Thompson examine gun violence in schools from…

  15. Grip-pattern recognition: Applied to a smart gun

    NARCIS (Netherlands)

    Shang, X.

    2008-01-01

    In our work the verification performance of a biometric recognition system based on grip patterns, as part of a smart gun for use by the police ocers, has been investigated. The biometric features are extracted from a two-dimensional pattern of the pressure, exerted on the grip of a gun by the hand

  16. Grip-pattern verification for a smart gun

    NARCIS (Netherlands)

    Shang, X.; Groenland, J.P.J.; Groenland, J.P.J.; Veldhuis, Raymond N.J.

    In the biometric verification system of a smart gun, the rightful user of the gun is recognized based on grip-pattern recognition. It was found that the verification performance of grip-pattern recognition degrades strongly when the data for training and testing the classifier, respectively, have

  17. Taking Aim at Gun Violence: Rebuilding Community Education & Employment Pathways

    Science.gov (United States)

    Bryant, Rhonda

    2013-01-01

    In January 2013, President Obama released a plan for protecting children and communities by reducing gun violence. This plan has generated serious debate from both sides of the issue. The ensuing conversations about how to solve the issue of gun violence have been volatile. The President's plan includes reforms to close loopholes on background…

  18. Gunning Mix or Converter and Electric Arc Furnace in China

    Institute of Scientific and Technical Information of China (English)

    LIUJie-hua; ZHANGYong-fang

    1996-01-01

    The increase of steel output by converter and electric are furnace has imposed a critical demand in quality and quantity on gunning mix in functioning a longer life of those de-vices linings.The paoer describes the consump-tion of gunning mix for converter and EAF and its recent development in variety and quality in China.

  19. Everyday Engineering: What Makes a Squirt Gun Squirt?

    Science.gov (United States)

    Moyer, Richard; Everett, Susan

    2009-01-01

    You may not think of engineering and squirt guns in the same sentence. However, like many examples of engineering design, the squirt gun pump mechanism is uncomplicated, yet elegant, and very inexpensive to manufacture. The design is widely used because of its simplicity and low cost. With only a few moving parts, it is able to deliver a stream of…

  20. NASCAP simulation of laboratory charging tests using multiple electron guns

    Science.gov (United States)

    Mandell, M. J.; Katz, I.; Parks, D. E.

    1981-01-01

    NASCAP calculations have been performed simulating exposure of a spacecraft-like model to multiple electron guns. The results agree well with experiment. It is found that magnetic field effects are fairly small, but substantial differential charging can result from electron gun placement. Conditions for surface flashover are readily achieved.

  1. Guns and Fear: A One-Way Street?

    Science.gov (United States)

    Hauser, Will; Kleck, Gary

    2013-01-01

    Surveys show that more than one half of gun owners report owning their firearm for self-protection. Although research has examined the effect of fear of crime on gun ownership, the issue of reciprocity and temporal order has been largely ignored. Furthermore, the effect of firearm acquisition and relinquishment on fear has not been evaluated…

  2. Normative Considerations in the Aftermath of Gun Violence in Schools

    Science.gov (United States)

    Gereluk, Dianne T.; Donlevy, J. Kent; Thompson, Merlin B.

    2015-01-01

    Gun violence in American and Canadian schools is an ongoing tragedy that goes substantially beyond its roots in the interlocking emotional and behavioral issues of mental health and bullying. In light of the need for effective policy development, Dianne T. Gereluk, J. Kent Donlevy, and Merlin B. Thompson examine gun violence in schools from…

  3. A 3 GHz photoelectron gun for high beam intensity

    CERN Document Server

    Bossart, Rudolf; Dehler, M; Godot, J C

    1996-01-01

    For the Compact Linear Collider Test Facility (CTF) at CERN a new rf gun with a laser driven photocathode is under construction. The new rf gun will replace the present 11/2 cell gun and will consist of 21/2 cells accelerating the beam to a momentum of 7.0 MeV/c with an electric field strength of 100 MV/m. The strong space-charge forces at low beam energy caused by the high charge density of the electron bunches are contained by radial and longitudinal rf focusing in the gun. The rf gun under construction has been optimized by MAFIA beam simulations for an injector assembly comprising a second accelerating rf structure and an intermediate solenoid magnet correcting the beam divergence of the 21/2 cell gun. The beam loading of the rf gun, by a train of 48 bunches with 21 nC charge each, causes a strong energy decay accompanied by an increase of the flight time for the bunches with lower energy. These effects can be corrected by slightly shifting the acceleration frequency of the gun. The experimental results...

  4. Changing of ballistic parameters from aged gun propellants

    NARCIS (Netherlands)

    Klerk, W.P.C. de; Driel, C.A. van

    2003-01-01

    The various properties of an SB and a DB gun propellant were investigated before and after artificial ageing. It was found that the decrease of nitrocellulose (NC) molecular weight, due to ageing of gun propellants, leads to a decrease of the mechanical integrity of the propellant grains. The effect

  5. American preferences for "smart" guns versus traditional weapons: Results from a nationwide survey.

    Science.gov (United States)

    Wallace, Lacey Nicole

    2016-12-01

    This study examines Americans' preferences regarding smart guns. The study builds on prior research by including previously unexamined factors, specifically victimization and comfort sharing gun ownership status with a doctor. Further, this study examines differences in preference patterns among gun owners and non-owners. Data were obtained from a nationwide online survey with 524 respondents in February 2016. The study finds that, among non-owners, older respondents and those with pro-gun attitudes are less likely to prefer smart guns to traditional firearms. Among gun owners, those with moderate political views, those with a history of victimization, and those residing in the Northeast are all more likely to prefer smart guns. Males and those with pro-gun attitudes are less likely to prefer smart guns. Education, income, race, marital status, presence of children in the home, and comfort discussing gun ownership with a doctor had no significant association with smart gun preference. Practical implications of these findings are discussed.

  6. Guns, Mental Illness, and the Law: Introduction to This Issue.

    Science.gov (United States)

    Swanson, Jeffrey W; Felthous, Alan R

    2015-06-01

    Firearm violence is a top-tier public health problem in the U.S., killing 33,563 and injuring an additional 81,396 people in 2012 (Centers for Disease Control and Prevention, CDC, ). Given constitutional protection and the cultural entrenchment of private gun ownership in the U.S., it is likely that guns will remain widely accessible--and largely unrestricted--for the foreseeable future. Therefore, most policies and laws intended to reduce firearm violence focus selectively on preventing "dangerous people" from having access to guns. That is a formidable challenge. How do we think productively about guns and mental illness in this context, and about the role of law in lessening the toll of gun violence? Copyright © 2015 John Wiley & Sons, Ltd.

  7. Status and running experience of the SRF gun at HZDR

    Energy Technology Data Exchange (ETDEWEB)

    Xiang, Rong; Arnold, Andre; Lu, Pengnan; Murcek, Petr; Teichert, Jochen; Vennekate, Hannes [Helmholtz Zentrum Dresden Rossendorf, 01328 Dresden (Germany)

    2015-07-01

    In order to achieve a high average current up to 1 mA with a low emittance of 1 mm mrad at 77 pC, an improved SRF gun has been installed and commissioned at HZDR since 2014. This new gun replaces the first 3.5-cell SRF gun at the superconducting linear accelerator ELBE which had been in operation since 2007. The new gun has been tested first with a Cu photocathode. The RF performance of the niobium cavity has been evaluated, the transverse and longitudinal beam parameters for low charge bunches have been measured, and the first beam has been guided into the ELBE beamline. The photocathode transfer system is also installed for the first high current beam test in 2015. In this contribution the status of the gun and the results of this first measurement period will be presented in detail.

  8. Status of the SRF Gun Operation at ELBE

    CERN Document Server

    Teichert, J; Buettig, H; Janssen, D; Justus, M; Lehnert, U; Michel, P; Murcek, P; Schneider, Ch; Schurig, R; Xiang, R; Kamps, T; Rudolph, J; Schenk, M; Klemz, G; Will, I; Staufenbiel, F

    2010-01-01

    The superconducting RF photo-injector (SRF gun) at FZD is the first operating electron injector of its kind. The gun with a 3½-cell cavity and a frequency of 1.3 GHz produces an electron beam of 3 MeV with a maximum bunch charge of about 400 pC. Also the design values for the acceleration gradient could not be reached with the cavity which is in use at present, the SRF gun will improve the beam quality for ELBE users. In the winter shutdown of 2009/10 the beam line was installed which connects the SRF gun with the ELBE accelerator. The paper reports on the first tests and on the progress in applying the SRF gun for ELBE operation.

  9. Cardiac stimulation with high voltage discharge from stun guns.

    Science.gov (United States)

    Nanthakumar, Kumaraswamy; Massé, Stephane; Umapathy, Karthikeyan; Dorian, Paul; Sevaptsidis, Elias; Waxman, Menashe

    2008-05-20

    The ability of an electrical discharge to stimulate the heart depends on the duration of the pulse, the voltage and the current density that reaches the heart. Stun guns deliver very short electrical pulses with minimal amount of current at high voltages. We discuss external stimulation of the heart by high voltage discharges and review studies that have evaluated the potential of stun guns to stimulate cardiac muscle. Despite theoretical analyses and animal studies which suggest that stun guns cannot and do not affect the heart, 3 independent investigators have shown cardiac stimulation by stun guns. Additional research studies involving people are needed to resolve the conflicting theoretical and experimental findings and to aid in the design of stun guns that are unable to stimulate the heart.

  10. Compact electron gun based on secondary emission through ionic bombardment.

    Science.gov (United States)

    Diop, Babacar; Bonnet, Jean; Schmid, Thomas; Mohamed, Ajmal

    2011-01-01

    We present a new compact electron gun based on the secondary emission through ionic bombardment principle. The driving parameters to develop such a gun are to obtain a quite small electron gun for an in-flight instrument performing Electron Beam Fluorescence measurements (EBF) on board of a reentry vehicle in the upper atmosphere. These measurements are useful to characterize the gas flow around the vehicle in terms of gas chemical composition, temperatures and velocity of the flow which usually presents thermo-chemical non-equilibrium. Such an instrument can also be employed to characterize the upper atmosphere if placed on another carrier like a balloon. In ground facilities, it appears as a more practical tool to characterize flows in wind tunnel studies or as an alternative to complex electron guns in industrial processes requiring an electron beam. We describe in this paper the gun which has been developed as well as its different features which have been characterized in the laboratory.

  11. Retrograde Signaling and Photoprotection in a gun4 Mutant of Chlamydomonas reinhardtii

    Institute of Scientific and Technical Information of China (English)

    Cinzia Formighieri; Mauro Ceol; Giulia Bonente; Jean-David Rochaix; Roberto Bassi

    2012-01-01

    GUN4 is a regulatory subunit of Mg-chelatase involved in the control of tetrapyrrole synthesis in plants and cyanobacteria.Here,we report the first characterization of a gun4 insertion mutant of the unicellular green alga Chlamydomonas reinhardtii.The mutant contains 50% of chlorophyll as compared to wild-type and accumulates ProtolX.In contrast to the increase in LHCtranscription,the accumulation of most LHC proteins is drastically diminished,implying posttranscriptional down-regulation in the absence of transcriptional coordination.We found that 803 genes change their expression level in gun4 as compared to wild-type,by RNA-Seq,and this wide-ranging effect on transcription is apparent under physiological conditions.Besides LHCs,we identified transcripts encoding enzymes of the tetrapyrrole pathway and factors involved in signal transduction,transcription,and chromatin remodeling.Moreover,we observe perturbations in electron transport with a strongly decreased PSI-to-PSII ratio.This is accompanied by an enhanced activity of the plastid terminal oxidase (PTOX) that could have a physiological role in decreasing photosystem Ⅱ excitation pressure.

  12. Pelapisan Alloy FeNiAl Menggunakan Metode Detonation Gun (D-Gun

    Directory of Open Access Journals (Sweden)

    M.R.T. Siregar

    2012-02-01

    Full Text Available Pelapisan material alloy Fe38Ni10Al dilakukan dengan metode D-Gun untuk meningkatkan kekerasan material Stainless Steel AISI 316 L. Analisis parameter proses dilakukan dengan perangkat statistik ANOVA (Analysis of Variance – Taguchi untuk memperoleh ukuran kristal, ketebalan dan tingkat kekerasan yang optimum. Lapisan paling tebal dimiliki oleh sampel SS03 sebesar 280 mikron, sedangkan sampel SS02 memiliki ketebalan paling rendah, 97 mikron. Ketebalan lapisan sangat dipengaruhi oleh laju aliran gas pembawa serbuk dengan rasio kontribusi sebesar 82, 7%. Kekerasan optimum diperoleh sampel SS08 dengan tingkat kekerasan sebesar 281,6 HV yang jauh lebih besar dari tingkat kekerasan Stainless Steel tanpa lapisan (195,0 HV. Analisis struktur dan ukuran kristal dilakukan dengan menggunakan XRD dan Metode Scherrer yang menghasilkan struktur kristal Taenite (γ-(Fe,Ni dengan ukuran kristal pada orde nanometer (nanokristal pada kisaran 27,5 hingga 37,7 nm. Ukuran kristal sangat dipengaruhi oleh parameter rasio gas asetilene – oksigen dengan rasio kontribusi 60,4 %. Kata kunci: Detonation Gun (D-Gun, ANOVA –Taguchi, XRD, Nanokristal, Metode Scherer, Tingkat Kekerasan (Hardness

  13. Gun culture and symbolism among U.K. and U.S. women.

    Science.gov (United States)

    Cooke, C A; Puddifoot, J E

    2000-08-01

    The authors explored attitudes of young women in the United Kingdom (n = 108) and the United States (n = 91) toward (a) the possession and use of guns through the Attitude to Guns Scale (N. R. Branscombe, J. A. Weir, & P. Crosby, 1992) and (b) guns' perceived functional and symbolic significance through the Symbolic Nature of Guns Scale (C. A. Cooke & J. E. Puddifoot, 1997). There were significant differences in beliefs concerning the right to own a gun and the protective effect of guns but not in the perceived contribution of guns to crime. Although neither group strongly equated guns symbolically with power or control, the U.S. women were more likely to perceive guns as expressions of freedom or independence, and the U.K. women were more likely to view guns as expressions of danger and violence. The findings were contextualized by comparison with samples of male control participants of similar ages.

  14. DAN PIENAAR GUN PARK LAUNCHES MUSEUM INTO 21ST CENTURY

    Directory of Open Access Journals (Sweden)

    C. Monick

    2012-02-01

    Full Text Available On 14 February 1992 there occurred the official opening of the Dan Pienaar Gun Park at the South African National Museum of Military History. The Gun Park is a newly completed exhibition area created by roofing and repairing the central courtyard between the exhibition's main halls. Lt Gen G L Meiring, SSA, SO, officially opened the Dan Pienaar Gun Park. The statue of Maj Gen D H ('Dan' Pienaar was officially unveiled by his widow (now Mrs Norma Seuffert. Maj Gen Pienaar's children, Fay, Barry and Nelia, were also present, in addition to a very wide representation of the Pienaar family.

  15. Dynamic Response and Fracture of Composite Gun Tubes

    Directory of Open Access Journals (Sweden)

    Jerome T. Tzeng

    2001-01-01

    Full Text Available The fracture behavior due to dynamic response in a composite gun tube subjected to a moving pressure has been investigated. The resonance of stress waves result in very high amplitude and frequency strains in the tube at the instant and location of pressure front passage as the velocity of the projectile approaches a critical value. The cyclic stresses can accelerate crack propagation in the gun tube with an existing imperfection and significantly shorten the fatigue life of gun tubes. The fracture mechanism induced by dynamic amplification effects is particularly critical for composite overwrap barrels because of a multi-material construction, anisotropic material properties, and the potential of thermal degradation.

  16. The internal ballistics of a high: low pressure gun

    Directory of Open Access Journals (Sweden)

    J. N. Kapur

    1957-04-01

    Full Text Available In the present paper the system of equations for the Non-Isothermal Model for a H/L gun has been developed and from this, the systems of equations for Isothermal and Non-isothermal models for orthodox gun and solid fuel rockets have been deduced. The Non-Isothermal Model for H/L gun has been integrated for a tubular charge. For isothermal model, reduction to an equivalent non-leaking problem has been discussed and the partially non-isothermal model has been integrated for the linear law. After all-burnt modification needed in Corner's energy equation is obtained.

  17. Ultra-low emittance X-band photocathode RF gun

    Institute of Scientific and Technical Information of China (English)

    TANG Chuan-Xiang; LIU Xiao-Han

    2009-01-01

    In this paper,we present the simulation results of a 1.6 cell X-band photocathode RF gun for ultra-low emittance electron beams.It will work at 9.3 GHz.The emittance,bunch length,electron energy and energy spread at the gun exit are optimized at bunch charge of 1pC using PARMELA.Electron bunches type coupler is adopted in this gun and an initial simulation by MAFIA is also given in this paper.

  18. Development of Subcaliber Projectiles for the Hispano-Suiza Gun

    Science.gov (United States)

    1943-11-01

    SUBOALIBER PRO JECTILES FOR THE HISPANO- SUIZA GUN 𔃺TECMEPUC-lT, TJ 0 ABERDEEN P 𔃺i7 CiiTDM. ST~lU-TL A T, 1?7,, by CTa * UG r C. L. Critchfield I P I, 2...FOR THE HISPANO- SUIZA GUN by C. L. Critchfield and J. McG. Millar TECiN•IcAr LITPP.py ABERDE " , :PT’- , Approved on November 12, 1943 for submission...Hispano- Suiza gun ....... 6 2. 20-ram sabot-projectiles of Series B and C ......... ... 12 3. Type C2 at h ft from the muzzle . .......... . 13 h. The 20

  19. Method of electron emission control in RF guns

    CERN Document Server

    Khodak, I V

    2001-01-01

    The electron emission control method for a RF gun is considered.According to the main idea of the method,the additional resonance system is created in a cathode region where the RF field strength could be varied using the external pulse equipment. The additional resonance system is composed of a coaxial cavity coupled with a RF gun cylindrical cavity via an axial hole. Computed results of radiofrequency and electrodynamic performances of such a two-cavity system and results of the RF gun model pilot study are presented in. Results of particle dynamics simulation are described.

  20. Energy partitioning in an inductively driven rail gun

    Science.gov (United States)

    Sen, K. K.; Ray, P. K.

    1984-01-01

    The equations describing the performance of an inductively driven rail are analyzed numerically. Friction between the projectile and rails is included through an empirical formulation. The equations are applied to the experiment of Rashleigh and Marshall to obtain an estimate of energy distribution in rail guns as a function of time. It is found that only 15 percent of energy delivered by the inductor to the gun is transformed into the kinetic energy of the projectile. This study provides an insight into the nature of nonlinear coupling involved in the electromechanical interactions in a rail gun.

  1. Projectile Balloting Attributable to Gun Tube Curvature

    Directory of Open Access Journals (Sweden)

    Michael M. Chen

    2010-01-01

    Full Text Available Transverse motion of a projectile during launch is detrimental to firing accuracy, structural integrity, and/or on-board electronics performance of the projectile. One manifest contributing factor to the undesired motion is imperfect bore centerline straightness. This paper starts with the presentation of a deterministic barrel model that possesses both vertical and lateral deviations from centerline in accordance with measurement data, followed by a novel approach to simulating comprehensive barrel centerline variations for the investigation of projectile balloting^1 motions. A modern projectile was adopted for this study. In-bore projectile responses at various locations of the projectile while traveling through the simulated gun tubes were obtained. The balloting was evaluated in both time and frequency domains. Some statistical quantities and the significance were outlined.

  2. Analysis of gun barrel rifling twist

    Science.gov (United States)

    Sun, Jia; Chen, Guangsong; Qian, Linfang; Liu, Taisu

    2017-05-01

    Aiming at the problem of gun barrel rifling twist, the constraint relation between rifling and projectile is investigated. The constraint model of rifling and projectile is established and the geometric relation between the twist and the motion of projectile is analyzed. Based on the constraint model, according to the rotating band that is fired, the stress and the motion law of the rotating band in bore are analyzed. The effects to rotating band (double rotating band or wide driving band) caused by different rifling (rib rifling, increasing rifling and combined rifling) are also investigated. The model is demonstrated by several examples. The results of numerical examples and the constraint mode show that the uncertainty factors will be brought in the increasing rifling and combined rifling during the projectile move in the bore. According to the amplitude and the strength of the twist acting on rotating band, the steady property of rotational motion of the projectile, the rib rifling is a better choose.

  3. Quantitative Testing of Defect for Gun Barrels

    Institute of Scientific and Technical Information of China (English)

    WANG Chang-long; JI Feng-zhu; WANG Jin; CHEN Zheng-ge

    2007-01-01

    The magnetic flux leakage (MFL) method is commonly used in the nondestructive evaluation (NDE) of gun barrels. The key point of MFL testing is to estimate the crack geometry parameters based on the measured signal. The analysis of magnetic leakage fields can be obtained by solving Maxwell's equations using finite element method (FEM).The radial component of magnetic flux density is measured in MFL testing. The peak-peak value, the separation distance between positive and negative peaks of signal and the lift-off value of Hall-sensor are used as the main features of every sample. This paper establishes the multi-regression equations related to the width (the depth) of crack and the main characteristic values. The regression model is tested by use of the magnetic leakage data. The experimental results indicate that the regression equations can accurately predict the 2-D defect geometry parameters and the MFL quantitative testing can be achieved.

  4. Smart Gun Technology project. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Weiss, D.R.

    1996-05-01

    The goal of the Smart Gun Technology project is to eliminate the capability of an unauthorized user form firing a law officer`s firearm by implementing user-recognizing-and-authorizing (or {open_quotes}smart{close_quotes}) surety technologies. This project was funded by the National Institute of Justice. This report lists the findings and results of the project`s three primary objectives. First, to find and document the requirements for a smart firearm technology that law enforcement officers will value. Second, to investigate, evaluate, and prioritize technologies that meet the requirements for a law enforcement officer`s smart firearm. Third, to demonstrate and document the most promising technology`s usefulness in models of a smart firearm.

  5. 手持式电子肌力测定仪在痉挛型脑瘫儿童下肢肌力测定中的信度研究%The reliability of hand-held electronic dynamometer tests for lower limb muscle strength measurement in children with spastic cerebral palsy

    Institute of Scientific and Technical Information of China (English)

    史惟; 朱默; 骆丹丹; 杨红; 陈冬冬; 黄华玉

    2010-01-01

    Objective To determine the reliability of hand-held electronic dynamometer (HHD) tests for lower limb muscle strength measurement in children with spastic cerebral palsy (CP). Methods Twenty-eight children ( 15 boys and 13 girls; mean age 5 years 8 months) with different types of CP (2 with spastic quadriplegia,8 spastic diplegia, 6 hemiplegia, 1 triplegia and 1 monoplegia) , and at different functional levels ( 19 graded at gross motor function classification system level Ⅰ, 6 level Ⅱ, 2 level Ⅲ and 1 level Ⅳ ) were recruited from the Rehabilitation Center of the Children's Hospital of Fudan University. Standardized HHD protocols were used to measure the strength of their hip, knee and ankle muscles. The HHD test was performed by the same examiner twice with an interval of 10 min in between. The HDD test was also performed with 15 randomly selected CP children by 2 examiners with an interval of 10 min in between. The test-retest and inter-rater reliabilities of the HDD readings were determined by calculating the intra- and inter-class correlation coefficients. Results The HHD measurements showed fine testretest reliability ( ICC = 0.74-0.97 ) and inter-rater reliability ( ICC = 0.63-0.97 ) in measuring lower-limb muscle strength of children with spastic CP, with the highest test-retest reliability for the hip flexion, foot plantar flexion and knee extension muscle groups. The highest inter-rater reliability was achieved with the hip flexion and foot dorsiflexion muscle groups. Conclusions Standardized HHD testing of lower-limb muscle strength in children with spastic CP shows fine test-retest and inter-rater reliability. The HHD can reliably assess the lower-limb muscle strength of children with spastic CP.%目的 探讨手持式电子肌力测定仪在痉挛型脑瘫儿童下肢肌力测定中的信度.方法 以2009年2月至11月在复旦大学附属儿科医院康复中心接受康复治疗的28例3岁以上的痉挛型脑瘫患儿为研究对象,采

  6. Brief use of a specific gun in a violent game does not affect attitudes towards that gun.

    Science.gov (United States)

    Hilgard, Joseph; Engelhardt, Christopher R; Bartholow, Bruce D

    2016-11-01

    Although much attention has been paid to the question of whether violent video games increase aggressive behaviour, little attention has been paid to how such games might encourage antecedents of gun violence. In this study, we examined how product placement, the attractive in-game presentation of certain real-world firearm brands, might encourage gun ownership, a necessary antecedent of gun violence. We sought to study how the virtual portrayal of a real-world firearm (the Bushmaster AR-15) could influence players' attitudes towards the AR-15 specifically and gun ownership in general. College undergraduates (N = 176) played one of four modified video games in a 2 (gun: AR-15 or science-fiction control) × 2 (gun power: strong or weak) between-subjects design. Despite collecting many outcomes and examining many potential covariates and moderators, experimental assignment did little to influence outcomes of product evaluations or purchasing intentions with regard to the AR-15. Attitudes towards public policy and estimation of gun safety were also not influenced by experimental condition, although these might have been better tested by comparison against a no-violence control condition. By contrast, gender and political party had dramatic associations with all outcomes. We conclude that, if product placement shapes attitudes towards firearms, such effects will need to be studied with stronger manipulations or more sensitive measures.

  7. Brief use of a specific gun in a violent game does not affect attitudes towards that gun

    Science.gov (United States)

    Engelhardt, Christopher R.; Bartholow, Bruce D.

    2016-01-01

    Although much attention has been paid to the question of whether violent video games increase aggressive behaviour, little attention has been paid to how such games might encourage antecedents of gun violence. In this study, we examined how product placement, the attractive in-game presentation of certain real-world firearm brands, might encourage gun ownership, a necessary antecedent of gun violence. We sought to study how the virtual portrayal of a real-world firearm (the Bushmaster AR-15) could influence players' attitudes towards the AR-15 specifically and gun ownership in general. College undergraduates (N = 176) played one of four modified video games in a 2 (gun: AR-15 or science-fiction control) × 2 (gun power: strong or weak) between-subjects design. Despite collecting many outcomes and examining many potential covariates and moderators, experimental assignment did little to influence outcomes of product evaluations or purchasing intentions with regard to the AR-15. Attitudes towards public policy and estimation of gun safety were also not influenced by experimental condition, although these might have been better tested by comparison against a no-violence control condition. By contrast, gender and political party had dramatic associations with all outcomes. We conclude that, if product placement shapes attitudes towards firearms, such effects will need to be studied with stronger manipulations or more sensitive measures. PMID:28018611

  8. Design of a Compact Coaxial Magnetized Plasma Gun for Magnetic Bubble Expansion Experiments

    Science.gov (United States)

    2009-06-01

    COAXIAL MAGNETIZED PLASMA GUN FOR MAGNETIC BUBBLE EXPANSION EXPERIMENTS Y. Zhang1, A. G. Lynn1, S. C. Hsu2, M. Gilmore1, C... coaxial magnetized plasma gun and its associated hardware systems are discussed in detail. The plasma gun is used for experimental studies of...and coaxial plasma guns - which is the method employed in this work. The first coaxial plasma gun experiment was performed five decades ago by

  9. Mystery of the First Russian Rifle Naval Guns

    Directory of Open Access Journals (Sweden)

    Nicholas W. Mitiukov

    2015-09-01

    Full Text Available In 1859 France completed the first ocean-going ironclad warship, «La Gloire», and changed the definition of naval power completely. Russia, as all the other Powers, found that her most powerful naval gun, the 60-pdr, was insufficient for modern warfare, and realized the future naval armament relied on heavy rifled artillery. Both the Army and Navy began purchasing such cannon from foreign providers until a suitable domestic weapon could be produced. The relationship between the Russian military and Krupp is well known. But there was another provided, the Blakely Ordnance Company in England sold many guns to the Army and Navy, beginning with 8-inch MLR in early 1863 to a large number of 9- and 11-inch guns. Deliveries began in November 1863 and continued until mid-1866. But no sources on the armament of Russian ships and fortresses mentions these guns. What happened to them is a mystery.

  10. Canvasback Gun Club : Submerged aquatic plant survey : 1986

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Flood waters which impacted the Stillwater Wildlife Management Area for the past several years also had their effect on the northern portions of the Canvasback Gun...

  11. Hartford's gun buy-back program: are we on target?

    Science.gov (United States)

    Marinelli, Laura W; Thaker, Shefali; Borrup, Kevin; Shapiro, David S; Bentley, George C; Saleheen, Hassan; Lapidus, Garry; Campbell, Brendan T

    2013-09-01

    Gunbuy-backprograms have been proposed as away to remove unwanted firearms from circulation, but remain controversial because their ability to prevent firearm injuries remains unproven. The purpose of this study is to describe the demographics of individuals participating in Connecticut's gun buy-backprogram in the context of annual gun sales and the epidemiology of firearm violence in the state. Over four years the buy-back program collected 464 firearms, including 232 handguns. In contrast, 91,602 firearms were sold in Connecticut during 2009 alone. The incidence of gun-related deaths was unchanged in the two years following the inception of the buy-back program. Suicide was associated with older age (mean = 51 +/- 18years) and Caucasian race (n = 539, 90%). Homicide was associated with younger age (mean = 30 +/- 12 years) and minority race (n = 425, 81%). A gun buy-back program alone is not likely to produce a measurable decrease in firearm injuries and deaths.

  12. Refractory Gunning Material for Inner Lining Maintenance of Blast Furnace

    Institute of Scientific and Technical Information of China (English)

    Yu Lingyan; Peng Xigao

    2010-01-01

    @@ 1 Scope This standard specifies the term and definition,classification, technical requirements, test methods,quality appraisal procedures, packing, marking, transportation, storage, and quality certificate of refractory gunning material for inner lining maintenance of blast furnace .

  13. Alternating Current All-electrical Gun Control System in Tanks

    Directory of Open Access Journals (Sweden)

    Zang Kemao

    2004-07-01

    Full Text Available The ac all-electrical gun control system is composed of permanent magnetic synchronous machine-drive control systems and the ball-screw by replacing the complicated electrohydraulic systems. At the same time, the variable-structure system with sliding modes makes the gun control systems to have higher performances using the only rate flexure gyroscope. Thereby, vehicle hull gyroscope and angular gyroscope are left out.The new ac all-electrical gun control systems developed are reduced by 40 per cent in weight, decreased by 30 per cent in volume, increased by 35 per cent in efficiency, and enhanced by three times in service life as compared to the current gun control systems.

  14. Cold Test Measurements on the GTF Prototype RF Gun

    Energy Technology Data Exchange (ETDEWEB)

    Gierman, S.M.

    2010-12-03

    The SSRL Gun Test Facility (GTF) was built to develop a high brightness electron injector for the LCLS and has been operational since 1996. Based on longitudinal phase space measurements showing a correlated energy spread the gun was removed and re-characterized in 2002. The low power RF measurements performed on the gun are described below. Perturbative bead measurements were performed to determine the field ratio in the two-cell gun, and network analyzer measurements were made to characterize the mode structure. A second probe was installed to monitor the RF field in the first cell, and a diagnostic was developed to monitor the high-power field ratio. Calibration of the RF probes, a model for analyzing RF measurements, and Superfish simulations of bead and RF measurements are described.

  15. Resistance Spot Welding with Middelfrequency-Inverter Weling Gun

    DEFF Research Database (Denmark)

    Rasmussen, Mogens H.

    The paper presents the results of investigations concerning the process stability and weldability lobes for uncoated sheets of 1.0 mm thickness when performing resistance spot welding with a middlefrequency-inverter welding gun......The paper presents the results of investigations concerning the process stability and weldability lobes for uncoated sheets of 1.0 mm thickness when performing resistance spot welding with a middlefrequency-inverter welding gun...

  16. Plasma gun with coaxial powder feed and adjustable cathode

    Science.gov (United States)

    Zaplatynsky, Isidor (Inventor)

    1991-01-01

    An improved plasma gun coaxially injects particles of ceramic materials having high melting temperatures into the central portion of a plasma jet. This results in a more uniform and higher temperature and velocity distribution of the sprayed particles. The position of the cathode is adjustable to facilitate optimization of the performance of the gun wherein grains of the ceramic material are melted at lower power input levels.

  17. Resistance Spot Welding with Middelfrequency-Inverter Weling Gun

    DEFF Research Database (Denmark)

    Rasmussen, Mogens H.

    The paper presents the results of investigations concerning the process stability and weldability lobes for uncoated sheets of 1.0 mm thickness when performing resistance spot welding with a middlefrequency-inverter welding gun......The paper presents the results of investigations concerning the process stability and weldability lobes for uncoated sheets of 1.0 mm thickness when performing resistance spot welding with a middlefrequency-inverter welding gun...

  18. Efficiency of guns from the technical point of view

    Directory of Open Access Journals (Sweden)

    G. Baranski

    1953-01-01

    Full Text Available From the engineering point of view, a gun or machine gun is a heat engine very similar to a Diesel or petrol engine. It has to do work when-operated by a soldier. A fuel is burnt, namely the propellant, and certain power (energy per unit time is obtained, namely the kinetic energy of the projectile for each interval of rounds fired.

  19. RF gun for an intense THz radiation source

    Institute of Scientific and Technical Information of China (English)

    GU Qiang; ZHAO Zhen-Tang; TONG De-Chun; CHEN Li-Fang; XU Xiu-Min

    2008-01-01

    A new facility is under construction at the Shanghai Institute of Applied Physics,to generate femto-second electron bunches and intense coherent THz radiation pulses.A thermionic RF-gun is used to be the electron source of the linac,which is 1.6 cell,π/2,side coupled in design.In the following of this paper,the design,manufacture and beam operation of this gun are presented.

  20. PREVENTING SCHOOL SHOOTINGS : A PUBLIC HEALTH APPROACH TO GUN VIOLENCE

    OpenAIRE

    Welch, Edward

    2013-01-01

    CHDS State/Local Gun violence in America must be addressed at the highest levels of society. Newtown, Aurora, and Virginia Tech were attacks on the very fabric of America. School shootings represent attacks on our nations future. A public health approach to gun violence focuses on prevention. Public safety professionals, educators and community leaders are squandering opportunities to prevent horrific acts of extreme violence. Preparedness is derived by planning, which is critical to mobil...

  1. Nitramine-Based High Energy Propellant Compositions for Tank Guns

    OpenAIRE

    R.S. Damse; Haridwar Singh

    2000-01-01

    Six different RDX-based gun propellant compositions have been formulated and studied to select the most suitable composition for tank gun ammunition in terms of higher force constant at relatively lower flame temperature (T). Ballistic'performance of the compositions was evaluated on the basis of closed vessel test. JIea(energy was determined using a bomb calorimeter. Sensitivity, thermal characteristics, stability and mechanical properties of the compositions were studied for assessing their...

  2. The Mystery of the Gun Turret in the Desert

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, R. D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-11-30

    The mystery of the gun turret in the desert began with an ingenious idea: to develop a reusable open-air line of sight diagnostic device to support LLNL’s early nuclear weapons development efforts. Obtained from the Mare Island Navy Shipyard (MINS) in January 1957, the gun turret traveled by ship to the Naval Construction Battalion base at Port Hueneme, California, and then by truck to Area 2 in the Yucca Flats valley at the Nevada Nuclear Security Site (NNSS).

  3. Cylinder expansion test and gas gun experiment comparison

    Energy Technology Data Exchange (ETDEWEB)

    Harrier, Danielle [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-06-30

    This is a summer internship presentation by the Hydro Working Group at Los Alamos National Laboratory (LANL) and goes into detail about their cylinder expansion test and gas gun experiment comparison. Specifically, the gas gun experiment is detailed along with applications, the cylinder expansion test is detailed along with applications, there is a comparison of the methods with pros and cons and limitations listed, the summer project is detailed, and future work is talked about.

  4. Engineering design of the PLX- α coaxial gun

    Science.gov (United States)

    Cruz, Edward; Brockington, Samuel; Case, Andrew; Luna, Marco; Witherspoon, Douglas; Langendorf, Samuel

    2016-10-01

    We describe the engineering and technical aspects of the coaxial gun designed for the 60-gun scaling study of spherically imploding plasma liners as a standoff driver for plasma-jet-driven magneto-inertial fusion. Each coaxial gun incorporates a fast, dense gas injection and triggering system, a compact low-weight pfn with integral sparkgap switching, and a contoured gap designed to suppress the blow-by instability. Alpha1 and Alpha2 guns are compared, with emphasis on the improvements on Alpha2, which include a faster more robust gas valve, an improved electrode contour, a custom 600- μF, 5-kV pfn, and a set of six inline sparkgap switches operated in parallel. The switch and pfn configurations are mounted directly to the back of the gun, and are designed to reduce inductance, cost, and complexity, maximize efficiency and system reliability, and ensure symmetric current flow. We will provide a detailed overview of the design choices made for the PLX- α coaxial gun. This work supported by the ARPA-E ALPHA Program.

  5. National attitudes concerning gun carrying in the United States.

    Science.gov (United States)

    Hemenway, D; Azrael, D; Miller, M

    2001-12-01

    To determine public attitudes in the United States concerning gun carrying. In the past 15 years, many state legislatures have passed laws making it easier for United States citizens to carry concealed firearms, not only on the street but into various locations, including churches and government buildings. National random digit dial telephone surveys conducted in 1996 and 1999 asked questions concerning the public's feelings of safety as more people in their community carry firearms, and whether, in the language of the question, respondents believe "regular" citizens should be allowed to carry guns into public or government buildings. Americans feel less safe rather than more safe as more people in their community begin to carry guns. By margins of at least nine to one, Americans do not believe that "regular" citizens should be allowed to bring their guns into restaurants, college campuses, sports stadiums, bars, hospitals, or government buildings. The public believes that increased gun carrying by others reduces rather than increases their safety. Overwhelmingly, the public believes that in many venues gun carrying should be prohibited.

  6. Contoured-gap coaxial guns for imploding plasma liner experiments

    Science.gov (United States)

    Witherspoon, F. D.; Case, A.; Brockington, S.; Cassibry, J. T.; Hsu, S. C.

    2014-10-01

    Arrays of supersonic, high momentum flux plasma jets can be used as standoff compression drivers for generating spherically imploding plasma liners for driving magneto-inertial fusion, hence the name plasma-jet-driven MIF (PJMIF). HyperV developed linear plasma jets for the Plasma Liner Experiment (PLX) at LANL where two guns were successfully tested. Further development at HyperV resulted in achieving the PLX goal of 8000 μg at 50 km/s. Prior work on contoured-gap coaxial guns demonstrated an approach to control the blowby instability and achieved substantial performance improvements. For future plasma liner experiments we propose to use contoured-gap coaxial guns with small Minirailgun injectors. We will describe such a gun for a 60-gun plasma liner experiment. Discussion topics will include impurity control, plasma jet symmetry and topology (esp. related to uniformity and compactness), velocity capability, and techniques planned for achieving gun efficiency of >50% using tailored impedance matched pulse forming networks. Mach2 and UAH SPH code simulations will be included. Work supported by US DOE DE-FG02-05ER54810.

  7. Advanced Concepts of the Propulsion System for the Futuristic Gun Ammunition

    Directory of Open Access Journals (Sweden)

    R.S. Darnse

    2003-10-01

    Full Text Available This review paper reports various concepts of the gun propulsion system to meet the goal of the futuristic hypervelocity projectiles. The nonconventional concepts, such as liquid gun propellant, rail gun, coil gun, electrothermal gun, electrothermal chemical gun along with conventional energetic solid gun propellant have been discussed. Even though muzzle velocity around 2000 m/s has been claimed to be achieved using such nonconventional propulsion systems, it will take quite some time before such systems are in regular use in the battlefield. Hence, solid gun propellants containing novel energetic ingredients (binders, plasticisers, and oxidisers would continue to be used in the near future and are expected to meet the requirements of the futuristic gun ammunition.

  8. Age, Poverty, Homicide, and Gun Homicide

    Directory of Open Access Journals (Sweden)

    Mike Males

    2015-03-01

    Full Text Available Traditional theories of “adolescent risk taking” have not been validated against recent research indicating that youthful traffic crash, violent crime, felony crime, and firearms mortality rates reflect young people’s low-socio-economic status (SES compared with older adults’, not young age. Aside from a small number of recent, conflicting studies, the literature gap on this key issue remains. The present study examines the 54,094 homicide deaths, including 41,123 gun homicides, victimizing California residents ages 15 to 69 during 1991 to 2012 by poverty status. Without controlling for poverty, homicide rates display the traditional age-curve peaking at 19, then declining. When poverty is controlled, the traditional age-curve persists only for high-poverty populations, in which young people are vastly over-represented, and homicide rates are elevated for all ages. This finding reiterates that “adolescent risk taking” may be an artifact of failing to control for age-divergent SES.

  9. A novel electron gun for inline MRI-linac configurations

    Energy Technology Data Exchange (ETDEWEB)

    Constantin, Dragoş E., E-mail: dragos.constantin@varian.com; Fahrig, Rebecca [Department of Radiology, Stanford University, Stanford, California 94305 (United States); Holloway, Lois [Liverpool and Macarthur Cancer Therapy Centres, The University of Sydney, NSW 2006 (Australia); Keall, Paul J. [Radiation Physics Laboratory, The University of Sydney, NSW 2006 (Australia)

    2014-02-15

    Purpose: This work introduces a new electron gun geometry capable of robust functioning in the presence of a high strength external magnetic field for axisymmetric magnetic resonance imaging (MRI)-linac configurations. This allows an inline MRI-linac to operate without the need to isolate the linear accelerator (linac) using a magnetic shield. This MRI-linac integration approach not only leaves the magnet homogeneity unchanged but also provides the linac flexibility to move along the magnet axis of symmetry if the source to target distance needs to be adjusted. Methods: Simple electron gun geometry modifications of a Varian 600C electron gun are considered and solved in the presence of an external magnetic field in order to determine a set of design principles for the new geometry. Based on these results, a new gun geometry is proposed and optimized in the fringe field of a 0.5 T open bore MRI magnet (GE Signa SP). A computer model for the 6 MeV Varian 600C linac is used to determine the capture efficiency of the new electron gun-linac system in the presence of the fringe field of the same MRI scanner. The behavior of the new electron gun plus the linac system is also studied in the fringe fields of two other magnets, a 1.0 T prototype open bore magnet and a 1.5 T GE Conquest scanner. Results: Simple geometrical modifications of the original electron gun geometry do not provide feasible solutions. However, these tests show that a smaller transverse cathode diameter with a flat surface and a slightly larger anode diameter could alleviate the current loss due to beam interactions with the anode in the presence of magnetic fields. Based on these findings, an initial geometry resembling a parallel plate capacitor with a hole in the anode is proposed. The optimization procedure finds a cathode-anode distance of 5 mm, a focusing electrode angle of 5°, and an anode drift tube length of 17.1 mm. Also, the linac can be displaced with ±15 cm along the axis of the 0.5 T

  10. Rheological and Adhesive Behavior of Gunning Mix for Blast Furnace Repair

    Institute of Scientific and Technical Information of China (English)

    CAO Feng; LONG Shigang; WU Xingrong; SUN Jialin; HONG Yanruo

    2003-01-01

    The aim of this experimental work was to investigate the rheological and adhesive performance of gunning mix suspensions. The results of rheological tests indicate that:the rheological curve of gunning mix bonded by high-alumina cement (HACG) is Bingham type; the rheological curve of low cement gunning mix (LCG) bonded by microsilica is characterized by pseudo-plasticity fluid with yielding stress; and the rheological property of low-cement gunning mix bonded by microsilica is proved to be better than that of gunning mix bonded by cement. Meanwhile as indicated by the adhesive tests: the better the rheological properties of gunning mix suspension, the better the repair effect would be.

  11. Different spectrum of Arabidopsis CHLH/GUN5 protein functions in tetrapyrrole metabolism, plastid signaling and ABA responses in guard cells

    Directory of Open Access Journals (Sweden)

    Harue Ibata

    2016-11-01

    Full Text Available Expression of Photosynthesis-Associated Nuclear Genes (PhANGs is controlled by environmental stimuli and plastid-derived signals (plastid signals transmitting the developmental and functional status of plastids to the nucleus. Arabidopsis genomes uncoupled (gun mutants exhibit defects in plastid signaling, leading to ectopic expression of PhANGs in the absence of chloroplast development. GUN5 encodes the plastid-localized Mg-chelatase enzyme subunit (CHLH, and recent studies suggest that CHLH is a multifunctional protein involved in tetrapyrrole biosynthesis, plastid signaling and ABA responses in guard cells. To understand the basis of CHLH multifunctionality, we investigated fifteen gun5 missense mutant alleles and transgenic lines expressing a series of truncated CHLH proteins in a severe gun5 allele (cch background (tCHLHs, ten different versions. Here, we show that Mg-chelatase function and plastid signaling are generally correlated; in contrast, based on the analysis of the gun5 missense mutant alleles, ABA-regulated stomatal control is distinct from these two other functions. We found that none of the tCHLHs could restore plastid-signaling or Mg-chelatase functions. Additionally, we found that both the C-terminal half and N-terminal half of CHLH function in ABA-induced stomatal movement.

  12. Gun availability and use of guns for suicide, homicide, and murder in Canada.

    Science.gov (United States)

    Bridges, F Stephen; Kunselman, Julie C

    2004-04-01

    A reliability check of Lester's (2000b) 1970-1995 time series that examined associations between the availability of firearms and their use for homicide and suicide in Canada. For the period 1974 to 1999, the relative availability of firearms as measured by the rate of accidental death from firearms and the average of the percentages of suicides + homicides using firearms was positively associated with the rate of homicide by firearms but not negatively associated with the rate of homicide by all other methods, and positively associated with the rate of suicide by firearms and negatively associated with the rate of suicide by all other methods. Correlations for the homicide versus murder rates, homicide rate using guns versus murder rate using guns, and homicide rate by all other methods versus murder rate by all other methods were very similar. There was a decrease over time of total suicide and homicide rates and firearm suicide and homicide rates, and with a slight indication of substitution of other methods for suicide.

  13. Background Checks for all Gun Buyers and Gun Violence Restraining Orders: State Efforts to Keep Guns from High-Risk Persons.

    Science.gov (United States)

    Vernick, Jon S; Alcorn, Ted; Horwitz, Joshua

    2017-03-01

    There were more than 36,000 firearm-related deaths in the U.S. in 2015. Under federal law, a background check is required only for gun purchases from licensed dealers. Research suggests that some persons prohibited from owning a gun turn to private sellers, including those identified online, to attempt to obtain a firearm. State-level approaches to make it more difficult for high-risk persons to purchase or possess firearms include universal background check (UBC) and gun violence restraining order (GVRO) laws. UBC laws, on the books in 18 states as of the end of 2016, can reduce both homicide and suicide rates. After Colorado adopted a UBC law in 2013, the number of background checks conducted by private sellers for sales occurring at places other than gun shows steadily increased. GVRO laws give law enforcement and families the authority to petition a court to temporarily remove firearms from an individual who presents a danger to himself or others during times of crisis, regardless of whether that person has been diagnosed with a mental illness. California enacted a GVRO law in 2014. Data are emerging to suggest the effectiveness of GVRO-type laws at averting suicides and providing an entryway to services.

  14. rf traveling-wave electron gun for photoinjectors

    Science.gov (United States)

    Schaer, Mattia; Citterio, Alessandro; Craievich, Paolo; Reiche, Sven; Stingelin, Lukas; Zennaro, Riccardo

    2016-07-01

    The design of a photoinjector, in particular that of the electron source, is of central importance for free electron laser (FEL) machines where a high beam brightness is required. In comparison to standard designs, an rf traveling-wave photocathode gun can provide a more rigid beam with a higher brightness and a shorter pulse. This is illustrated by applying a specific optimization procedure to the SwissFEL photoinjector, for which a brightness improvement up to a factor 3 could be achieved together with a double gun output energy compared to the reference setup foreseeing a state-of-the-art S-band rf standing-wave gun. The higher brightness is mainly given by a (at least) double peak current at the exit of the gun which brings benefits for both the beam dynamics in the linac and the efficiency of the FEL process. The gun design foresees an innovative coaxial rf coupling at both ends of the structure which allows a solenoid with integrated bucking coil to be placed around the cathode in order to provide the necessary focusing right after emission.

  15. Study of a laser-heated electron gun

    Science.gov (United States)

    Roy, P. K.; Moon, A.; Mima, K.; Nakai, S.; Fujita, M.; Imasaki, K.; Yamanaka, C.; Yasuda, E.; Watanabe, T.; Ohigashi, N.; Okuda, Y.; Tsunawaki, Y.

    1996-12-01

    A method of cathode heating using a laser was studied for an electron gun. In order to observe the practicality of the heating system, the characteristics of the laser-heated gun with a dispenser and LaB6 thermionic cathodes have been experimentally investigated. The direct laser irradiation is so efficient that the gun is equipped without heat shielding, a cooling system, or an electrical circuit in the gun chamber for cathode heating. Modeling, based on the experimental data, indicates that the cathode temperature is proportional to one-fourth power of the laser power and that laser power loss and conduction loss of heat in the gun assembly are negligible. An electron beam current density 0.48 A/cm2 was measured with 26 W laser power for a dispenser cathode of 0.06 cm2 emission area. Current density 0.16 A/cm2 with 25 W was recorded for a LaB6 cathode of area 0.12 cm2. Electron beam emittance has been measured by using the typical pepper-pot technique. It was observed that the growth of electron beam emittance was very small in the laser heating.

  16. Operation of the superconducting RF photo gun at ELBE

    CERN Document Server

    Teichert, J; Buettig, H; Janssen, D; Justus, M; Lehnert, U; Michel, P; Murcek, P; Schneider, Ch; Schurig, R; Staufenbiel, F; Xiang, R; Kamps, T; Rudolph, J; Schenk, M; Klemz, G; Will, I

    2012-01-01

    As the first superconducting RF photo-injector (SRF gun) in practical operation, the SRF gun has been successfully connected to the superconducting linac ELBE at Forschungzentrum Dresden-Rossendorf. The injection with this new gun will improve the beam quality for the users of the radiation source. The SRF gun contains a 3½ cell superconducting accelerating cavity with a frequency of 1.3 GHz. The design is for use of normal conducting photocathodes. At present, caesium telluride photocathodes are applied which are illuminated by an ultraviolet laser beam. The kinetic energy of the produced electron beam is 3 MeV which belongs to a peak electric field of 16 MV/m in the cavity. The maximum bunch charge which is obtained and measured in a Faraday cup is about 400 pC (20 μA average current at a repetition rate of 50 kHz). The SRF gun injector is connected to the ELBE accelerator via a dogleg with two 45° deflection magnets. This connection beam line was commissioned in January 2010. A first beam injection into...

  17. Operation of the superconducting RF photo gun at ELBE

    CERN Document Server

    Teichert, J; Buettig, H; Janssen, D; Justus, M; Lehnert, U; Michel, P; Murcek, P; Schneider, C; Schurig, R; Staufenbiel, F; Xiang, R; Kamps, T; Rudolph, J; Schenk, M; Klemz, G; Will, I

    2011-01-01

    As the first superconducting RF photo-injector (SRF gun) in practical operation, the SRF gun has been successfully connected to the superconducting linac ELBE at Forschungzentrum Dresden-Rossendorf. The injection with this new gun will improve the beam quality for the users of the radiation source. The SRF gun contains a 3½ cell superconducting accelerating cavity with a frequency of 1.3 GHz. The design is for use of normal conducting photocathodes. At present, caesium telluride photocathodes are applied which are illuminated by an ultraviolet laser beam. The kinetic energy of the produced electron beam is 3 MeV which belongs to a peak electric field of 16 MV/m in the cavity. The maximum bunch charge which is obtained and measured in a Faraday cup is about 400 pC (20 µA average current at a repetition rate of 50 kHz). The SRF gun injector is connected to the ELBE accelerator via a dogleg with two 45° deflection magnets. This connection beam line was commissioned in January 2010. A first beam injection into...

  18. Strong gun laws are not enough: the need for improved enforcement of secondhand gun transfer laws in Massachusetts.

    Science.gov (United States)

    Braga, Anthony A; Hureau, David M

    2015-10-01

    Research suggests that an overwhelming majority of crime guns were transferred by private sellers before recovery by law enforcement. Unfortunately, most states do not regulate these transactions. This study examines whether analyses of state-level private transfer data could be used to develop interventions to reduce the supply of handguns to violent criminals. Traced Boston crime handguns first sold at Massachusetts license dealers were matched to state secondhand gun transfer data. Logistic regression and descriptive statistics were used to analyze the characteristics of recovered crime guns and in-state primary and secondary market transaction patterns. For crime handguns with records of secondary market transactions in Massachusetts, many rapidly move from private transfer to recovery by the police. Unfortunately, important transaction data on the in-state sources of nearly 63% of recovered handguns were not readily available to law enforcement agencies. Data on private transfers of guns could be used to prevent violent injuries by reducing criminal access. However, the passage of strong private transfer gun laws needs to be accompanied by investments in the vigorous enforcement of reporting requirements. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Emittance Measurements of the SSRL Gun Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez, Michael; Clendenin, James; Fisher, Alan; Miller, Roger; Palmer, Dennis; Park, Sam; Schmerge, John; Weaver, Jim; Wiedemann, Helmut; Winick, Herman; Yeremian, Dian; /SLAC; Meyerhofer, David; Reis, David; /Rochester U.

    2011-09-01

    A photocathode RF gun test stand is under construction in the injector vault of the Stanford Synchrotron Radiation Laboratory at SLAC. The goal of this facility is to produce an electron beam with a normalized emittance of 1-3[mm-mr], a longitudinal bunch duration of the order of 10[ps] FWHM and approximately 1[nC] of charge per bunch. The beam will be generated from a laser driven copper photocathode RF gun developed in collaboration with BNL, LBL and UCLA. The 3-5[MeV] beam from the gun will be accelerated using a SLAC three meter S-band accelerator section. The emittance of the electron beam will be measured through the use of quadrupole scans with phosphor screens and also a wire scanner. The details of the experimental setup will be discussed, and first measurements will be presented and compared with results from PARMELA simulations.

  20. Rf Gun with High-Current Density Field Emission Cathode

    Energy Technology Data Exchange (ETDEWEB)

    Jay L. Hirshfield

    2005-12-19

    High current-density field emission from an array of carbon nanotubes, with field-emission-transistor control, and with secondary electron channel multiplication in a ceramic facing structure, have been combined in a cold cathode for rf guns and diode guns. Electrodynamic and space-charge flow simulations were conducted to specify the cathode configuration and range of emission current density from the field emission cold cathode. Design of this cathode has been made for installation and testing in an existing S-band 2-1/2 cell rf gun. With emission control and modulation, and with current density in the range of 0.1-1 kA/cm2, this cathode could provide performance and long-life not enjoyed by other currently-available cathodes