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Sample records for hamilton montgomery preble

  1. Sir William Rowan Hamilton

    Indian Academy of Sciences (India)

    IAS Admin

    In this picture, wave fronts are defined as surfaces of constant S(x), while .... Recall here that physical quantities are represented in ... his memory imperishable? Hamilton ... self in the words Ptolemy used of Hipparchus: a lover of labour and a ...

  2. Hamilton : the electric city

    Energy Technology Data Exchange (ETDEWEB)

    Gilbert, R [Richard Gilbert Consultant, Toronto, ON (Canada)

    2006-04-13

    The City of Hamilton has launched an extensive energy planning exercise that examines the possibility of steep increases in oil and natural gas prices. This report examined and illustrated the issue of oil and gas price points. The report also examined and presented the city's role in an era of energy constraints, focusing on the city's transit system and its vehicle fleet. In addition, in response to City Council's direction, the report presented the aerotropolis proposal and discussed freight transport issues. Specific topics of discussion included oil and natural gas prospects; prospects for high oil and natural gas prices; impacts of fuel price increases; strategic planning objectives for energy constraints; reducing energy use by Hamilton's transport and in buildings; and land-use planning for energy constraints. Energy production opportunities involve the use of solar energy; wind energy; deep lake water cooling (DLWC); hydro-electric power; energy from waste; biogas production; district energy; and local food production. Economic and social development through preparing for energy constraints and matters raised by city council were also presented. The report also demonstrated how an energy-based strategy could be paid for and its components approved. The next steps for Hamilton were also identified. refs., tabs., figs.

  3. Hamilton : the electric city

    International Nuclear Information System (INIS)

    Gilbert, R.

    2006-01-01

    The City of Hamilton has launched an extensive energy planning exercise that examines the possibility of steep increases in oil and natural gas prices. This report examined and illustrated the issue of oil and gas price points. The report also examined and presented the city's role in an era of energy constraints, focusing on the city's transit system and its vehicle fleet. In addition, in response to City Council's direction, the report presented the aerotropolis proposal and discussed freight transport issues. Specific topics of discussion included oil and natural gas prospects; prospects for high oil and natural gas prices; impacts of fuel price increases; strategic planning objectives for energy constraints; reducing energy use by Hamilton's transport and in buildings; and land-use planning for energy constraints. Energy production opportunities involve the use of solar energy; wind energy; deep lake water cooling (DLWC); hydro-electric power; energy from waste; biogas production; district energy; and local food production. Economic and social development through preparing for energy constraints and matters raised by city council were also presented. The report also demonstrated how an energy-based strategy could be paid for and its components approved. The next steps for Hamilton were also identified. refs., tabs., figs

  4. Hamilton's principle for beginners

    International Nuclear Information System (INIS)

    Brun, J L

    2007-01-01

    I find that students have difficulty with Hamilton's principle, at least the first time they come into contact with it, and therefore it is worth designing some examples to help students grasp its complex meaning. This paper supplies the simplest example to consolidate the learning of the quoted principle: that of a free particle moving along a line. Next, students are challenged to add gravity to reinforce the argument and, finally, a two-dimensional motion in a vertical plane is considered. Furthermore these examples force us to be very clear about such an abstract principle

  5. William Rowan Hamilton: Mathematical genius

    Energy Technology Data Exchange (ETDEWEB)

    Wilkins, D.R. [School of Mathematics, Trinity College, Dublin (Ireland)]. E-mail: dwilkins@maths.tcd.ie

    2005-08-01

    This year Ireland celebrates the bicentenary of the mathematician William Rowan Hamilton, best remembered for 'quaternions' and for his pioneering work on optics and dynamics. Two centuries after his birth, the extent to which terms such as 'Hamiltonian' and 'Hamiltonian system' have entered the everyday language of mathematicians and physicists testifies to the continuing impact of the scientific work of William Rowan Hamilton. (U.K.)

  6. William Rowan Hamilton: Mathematical genius

    International Nuclear Information System (INIS)

    Wilkins, D.R.

    2006-01-01

    This year Ireland celebrates the bicentenary of the mathematician William Rowan Hamilton, best remembered for quaternions and for his pioneering work on optics and dynamics. Two centuries after his birth, the extent to which terms such as Hamiltonian and Hamiltonian system have entered the everyday language of mathematicians and physicists testifies to the continuing impact of the scientific work of William Rowan Hamilton. (U.K.)

  7. Unified Symmetry of Hamilton Systems

    International Nuclear Information System (INIS)

    Xu Xuejun; Qin Maochang; Mei Fengxiang

    2005-01-01

    The definition and the criterion of a unified symmetry for a Hamilton system are presented. The sufficient condition under which the Noether symmetry is a unified symmetry for the system is given. A new conserved quantity, as well as the Noether conserved quantity and the Hojman conserved quantity, deduced from the unified symmetry, is obtained. An example is finally given to illustrate the application of the results.

  8. School Progress Report 2012. Montgomery County Public Schools

    Science.gov (United States)

    Montgomery County Public Schools, 2013

    2013-01-01

    The 2012 School Progress Report for Montgomery County Public Schools (MCPS) provides state, county, and individual school performance data, as well as information on student attendance, high school graduation rates, and the professional qualifications of teachers at the state, district, and school levels. Montgomery County primary schools are…

  9. High-Order Hamilton's Principle and the Hamilton's Principle of High-Order Lagrangian Function

    International Nuclear Information System (INIS)

    Zhao Hongxia; Ma Shanjun

    2008-01-01

    In this paper, based on the theorem of the high-order velocity energy, integration and variation principle, the high-order Hamilton's principle of general holonomic systems is given. Then, three-order Lagrangian equations and four-order Lagrangian equations are obtained from the high-order Hamilton's principle. Finally, the Hamilton's principle of high-order Lagrangian function is given.

  10. Hamilton-Jacobi theory of continuos systems

    International Nuclear Information System (INIS)

    Guler, Y.

    1987-01-01

    The Hamilton-Jacobi partial differential equation for classical field systems is obtained in a 5n-dimensional phase space and it is integrated by the method of characteristics. Space-time partial derivatives of Hamilton's principal functions S μ (Φ i , x v ) (μ, v = 1, 2, 3, 4) are identified as the energy-momentum tensor of the system

  11. Faster Double-Size Bipartite Multiplication out of Montgomery Multipliers

    Science.gov (United States)

    Yoshino, Masayuki; Okeya, Katsuyuki; Vuillaume, Camille

    This paper proposes novel algorithms for computing double-size modular multiplications with few modulus-dependent precomputations. Low-end devices such as smartcards are usually equipped with hardware Montgomery multipliers. However, due to progresses of mathematical attacks, security institutions such as NIST have steadily demanded longer bit-lengths for public-key cryptography, making the multipliers quickly obsolete. In an attempt to extend the lifespan of such multipliers, double-size techniques compute modular multiplications with twice the bit-length of the multipliers. Techniques are known for extending the bit-length of classical Euclidean multipliers, of Montgomery multipliers and the combination thereof, namely bipartite multipliers. However, unlike classical and bipartite multiplications, Montgomery multiplications involve modulus-dependent precomputations, which amount to a large part of an RSA encryption or signature verification. The proposed double-size technique simulates double-size multiplications based on single-size Montgomery multipliers, and yet precomputations are essentially free: in an 2048-bit RSA encryption or signature verification with public exponent e=216+1, the proposal with a 1024-bit Montgomery multiplier is at least 1.5 times faster than previous double-size Montgomery multiplications.

  12. The Hamilton Depression Scale (HAM-D) and the Montgomery–Åsberg Depression Scale (MADRS)

    DEFF Research Database (Denmark)

    Bech, Per; Allerup, Peter; Larsen, Erik Roj

    2014-01-01

    The objective of this re-analysis of the European Genome-Based Therapeutic Drugs for Depression Study (GENDEP) was to psychometrically test the unidimensionality of the full Montgomery Åsberg Depression Rating Scale (MADRS10) and the Hamilton Depression Scale (HAM-D17) versus their respective...... subscales (MADRS5 and HAM-D6) containing the core symptoms of depression severity. Rasch analysis was applied using RUMM 2030 software to assess the overall fit for unidimensionality. Neither the MADRS10 nor the HAM-D17 was found to fit the Rasch model for unidimensionality. The HAM-D6 (containing the items...... of depressed mood, guilt, work and interests, psychomotor retardation, psychic anxiety, and somatic general) as well as the analogue MADRS5 were tested for unidimensionality by use of the RUMM 2030 programme, and only the HAM-D6 was accepted. When testing for invariance across rating weeks or centres, the RUMM...

  13. Montgomery Point Lock and Dam, White River, Arkansas

    Science.gov (United States)

    2016-01-01

    the time of this study was James E. Walker, Chief, Navigation Branch, HQUSACE. W. Jeff Lillycrop, CHL, was the ERDC Technical Director for... Fischer , and J. Mewes. 2011. Montgomery Point Lock and Dam HSR model, White River miles 4.0 – 0.0; Hydraulic sediment response model investigation

  14. A High-Speed Design of Montgomery Multiplier

    Science.gov (United States)

    Fan, Yibo; Ikenaga, Takeshi; Goto, Satoshi

    With the increase of key length used in public cryptographic algorithms such as RSA and ECC, the speed of Montgomery multiplication becomes a bottleneck. This paper proposes a high speed design of Montgomery multiplier. Firstly, a modified scalable high-radix Montgomery algorithm is proposed to reduce critical path. Secondly, a high-radix clock-saving dataflow is proposed to support high-radix operation and one clock cycle delay in dataflow. Finally, a hardware-reused architecture is proposed to reduce the hardware cost and a parallel radix-16 design of data path is proposed to accelerate the speed. By using HHNEC 0.25μm standard cell library, the implementation results show that the total cost of Montgomery multiplier is 130 KGates, the clock frequency is 180MHz and the throughput of 1024-bit RSA encryption is 352kbps. This design is suitable to be used in high speed RSA or ECC encryption/decryption. As a scalable design, it supports any key-length encryption/decryption up to the size of on-chip memory.

  15. School Progress Report 2013. Montgomery County Public Schools

    Science.gov (United States)

    Montgomery County Public Schools, 2014

    2014-01-01

    The 2013 School Progress Report for Montgomery County Public Schools (MCPS) provides state, county, and individual school performance data, as well as information on student attendance, high school graduation rates, and the professional qualifications of teachers at the state, district, and school levels for the 2012-2013 school year. Montgomery…

  16. 76 FR 54188 - Television Broadcasting Services; Montgomery, AL

    Science.gov (United States)

    2011-08-31

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [MB Docket No. 11-137, RM-11637; DA 11-1414] Television Broadcasting Services; Montgomery, AL AGENCY: Federal Communications Commission. ACTION: Proposed... 47 CFR Part 73 Television, Television broadcasting. Federal Communications Commission. Barbara A...

  17. 76 FR 71909 - Television Broadcasting Services; Montgomery, AL

    Science.gov (United States)

    2011-11-21

    ... FEDERAL COMMUNICATIONS COMMISSION 47 CFR Part 73 [MB Docket No. 11-137; RM-11637, DA 11-1863] Television Broadcasting Services; Montgomery, AL AGENCY: Federal Communications Commission. ACTION: Final... CFR Part 73 Television. Federal Communications Commission. Barbara A. Kreisman, Chief, Video Division...

  18. Hamilton's indicators of the force of selection

    DEFF Research Database (Denmark)

    Baudisch, Annette

    2005-01-01

    To quantify the force of selection, Hamilton [Hamilton, W. D. (1966) J. Theor. Biol. 12, 12-45] derived expressions for the change in fitness with respect to age-specific mutations. Hamilton's indicators are decreasing functions of age. He concluded that senescence is inevitable: survival...... and fertility decline with age. I show that alternative parameterizations of mutational effects lead to indicators that can increase with age. I then consider the case of deleterious mutations with age-specific effects. In this case, it is the balance between mutation and selection pressure that determines...... the equilibrium number of mutations in a population. In this balance, the effects of different parameterizations cancel out, but only to a linear approximation. I show that mutation accumulation has little impact at ages when this linear approximation holds. When mutation accumulation matters, nonlinear effects...

  19. Fifty years with the Hamilton scales for anxiety and depression. A tribute to Max Hamilton.

    Science.gov (United States)

    Bech, P

    2009-01-01

    From the moment Max Hamilton started his psychiatric education, he considered psychometrics to be a scientific discipline on a par with biochemistry or pharmacology in clinical research. His clinimetric skills were in operation in the 1950s when randomised clinical trials were established as the method for the evaluation of the clinical effects of psychotropic drugs. Inspired by Eysenck, Hamilton took the long route around factor analysis in order to qualify his scales for anxiety (HAM-A) and depression (HAM-D) as scientific tools. From the moment when, 50 years ago, Hamilton published his first placebo-controlled trial with an experimental anti-anxiety drug, he realized the dialectic problem in using the total score on HAM-A as a sufficient statistic for the measurement of outcome. This dialectic problem has been investigated for more than 50 years with different types of factor analyses without success. Using modern psychometric methods, the solution to this problem is a simple matter of reallocating the Hamilton scale items according to the scientific hypothesis under examination. Hamilton's original intention, to measure the global burden of the symptoms experienced by the patients with affective disorders, is in agreement with the DSM-IV and ICD-10 classification systems. Scale reliability and obtainment of valid information from patients and their relatives were the most important clinimetric innovations to be developed by Hamilton. Max Hamilton therefore belongs to the very exclusive family of eminent physicians celebrated by this journal with a tribute. 2009 S. Karger AG, Basel.

  20. Measuring Social Capital in Hamilton, Ontario

    Science.gov (United States)

    Kitchen, Peter; Williams, Allison; Simone, Dylan

    2012-01-01

    Social capital has been studied by academics for more than 20 years and within the past decade there has been an explosion of growth in research linking social capital to health. This paper investigates social capital in Hamilton, Ontario by way of a telephone survey of 1,002 households in three neighbourhood groups representing high, mixed and…

  1. Algebra and Geometry of Hamilton's Quaternions

    Indian Academy of Sciences (India)

    2016-08-26

    Aug 26, 2016 ... ... Public Lectures · Lecture Workshops · Refresher Courses · Symposia. Home; Journals; Resonance – Journal of Science Education; Volume 21; Issue 6. Algebra and Geometry of Hamilton's Quaternions: 'Well, Papa, Can You Multiply Triplets?' General Article Volume 21 Issue 6 June 2016 pp 529-544 ...

  2. Hamiltonization of theories with degenerate coordinates

    International Nuclear Information System (INIS)

    Gitman, D.M.; Tyutin, I.V.

    2002-01-01

    We consider a class of Lagrangian theories where part of the coordinates does not have any time derivatives in the Lagrange function (we call such coordinates degenerate). We advocate that it is reasonable to reconsider the conventional definition of singularity based on the usual Hessian and, moreover, to simplify the conventional hamiltonization procedure. In particular, in such a procedure, it is not necessary to complete the degenerate coordinates with the corresponding conjugate momenta

  3. Hamiltonization of theories with degenerate coordinates

    Energy Technology Data Exchange (ETDEWEB)

    Gitman, D.M. E-mail: gitman@fma.if.usp.br; Tyutin, I.V. E-mail: tyutin@lpi.ru

    2002-05-27

    We consider a class of Lagrangian theories where part of the coordinates does not have any time derivatives in the Lagrange function (we call such coordinates degenerate). We advocate that it is reasonable to reconsider the conventional definition of singularity based on the usual Hessian and, moreover, to simplify the conventional hamiltonization procedure. In particular, in such a procedure, it is not necessary to complete the degenerate coordinates with the corresponding conjugate momenta.

  4. Fifty years with the Hamilton scales for anxiety and depression. A tribute to Max Hamilton

    DEFF Research Database (Denmark)

    Bech, P; Bech, P

    2009-01-01

    as the method for the evaluation of the clinical effects of psychotropic drugs. Inspired by Eysenck, Hamilton took the long route around factor analysis in order to qualify his scales for anxiety (HAM-A) and depression (HAM-D) as scientific tools. From the moment when, 50 years ago, Hamilton published his first...... placebo-controlled trial with an experimental anti-anxiety drug, he realized the dialectic problem in using the total score on HAM-A as a sufficient statistic for the measurement of outcome. This dialectic problem has been investigated for more than 50 years with different types of factor analyses without...

  5. Buying Renewable Electric Power in Montgomery County, Maryland

    Science.gov (United States)

    Cember, Richard P.

    2008-08-01

    From mid-August 2007 until mid-August 2008, my home electricity supply was 100% wind-generated. My experience in switching to wind-generated electric power may be of interest to fellow AGU members for three reasons. First, Montgomery County, Md., where I live, is one of the few jurisdictions in the United States that has both an electric power tax and a renewable energy credit. The county is therefore a case study in price-based public policy for greenhouse gas emissions control. Second, I was surprised by the comparatively small price difference (or ``price premium'') between wind-generated and conventionally generated power in the county, and I believe that Eos readers will be similarly surprised. Third, because so many U.S. federal agencies concerned with Earth science are based in the Washington, D. C., area, a high concentration of AGU members live in Montgomery County and may be personally interested in evaluating the price of reducing carbon dioxide emissions from the generation of their own residential electricity.

  6. Role of Montgomery T-tube stent for laryngotracheal stenosis.

    Science.gov (United States)

    Prasanna Kumar, Saravanam; Ravikumar, Arunachalam; Senthil, Kannan; Somu, Lakshman; Nazrin, Mohd Ismail

    2014-04-01

    To identify the indications, complications and outcome of patients of LTS managed with Montgomery T-tube stenting and review the current literature about the role of stenting in LTS. Retrospective chart reviews of 39 patients of laryngotracheal stenosis managed by T-tube stenting for temporary or definitive treatment during the period 2004-2011 were considered. The data on indications for stenting, type of stent, problems/complications of stenting, duration of stenting, additional intervention and outcome of management were collected, tabulated and analyzed. Of the 51 cases of laryngotracheal stenosis 39 patients were treated by Montgomery T-tube stenting. There was no mortality associated with the procedure or stenting. 82% of the patients were successfully decannulated. The problems and complications encountered were crusting within the tube in 44% and granulation at the subglottis in 33%. Two patients had complication due to T-tube itself: One patient developed tracheomalacia and the other had stenosis at both ends of the T-tube. Stenting still has a role in management of inoperable or in some deadlock situations where resection anastomosis is not feasible. It is easier to introduce the stent and to maintain it. Complications are minor and can be managed easily. It is safe for long term use. We emphasize that the treating surgeon needs to use prudence while treating stenosis using stents. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  7. Viscous warm inflation: Hamilton-Jacobi formalism

    Science.gov (United States)

    Akhtari, L.; Mohammadi, A.; Sayar, K.; Saaidi, Kh.

    2017-04-01

    Using Hamilton-Jacobi formalism, the scenario of warm inflation with viscous pressure is considered. The formalism gives a way of computing the slow-rolling parameter without extra approximation, and it is well-known as a powerful method in cold inflation. The model is studied in detail for three different cases of the dissipation and bulk viscous pressure coefficients. In the first case where both coefficients are taken as constant, it is shown that the case could not portray warm inflationary scenario compatible with observational data even it is possible to restrict the model parameters. For other cases, the results shows that the model could properly predicts the perturbation parameters in which they stay in perfect agreement with Planck data. As a further argument, r -ns and αs -ns are drown that show the acquired result could stand in acceptable area expressing a compatibility with observational data.

  8. Hamilton y el Descubrimiento de los Cuaterniones

    Directory of Open Access Journals (Sweden)

    José Manuel Sánchez Muñoz

    2011-10-01

    Full Text Available Este artículo pretende ofrecer una visión general del descubrimiento de los llamados cuaterniones por parte del matemático irlandés William Rowan Hamilton. Se pretende dar al lector algunos detalles del nacimiento de los números imaginarios en el siglo XVI, su interpretación geométrica a principios del siglo XIX, y la extensión del plano complejo a las tres dimensiones a través de los cuaterniones, que abrirían el paso al estudio y el desarrollo de las nuevas álgebras no conmutativas y a una nueva interpretación tridimensional de la realidad física.

  9. Hamilton-Jacobi-Bellman equations for quantum control | Ogundiran ...

    African Journals Online (AJOL)

    The aim of this work is to study Hamilton-Jacobi-Bellman equation for quantum control driven by quantum noises. These noises are annhihilation, creation and gauge processes. We shall consider the solutions of Hamilton-Jacobi-Bellman equation via the Hamiltonian system measurable in time. JONAMP Vol. 11 2007: pp.

  10. 78 FR 9001 - Airworthiness Directives; Hamilton Sundstrand Corporation Propellers

    Science.gov (United States)

    2013-02-07

    ... airplane. The Hamilton Sundstrand investigation revealed some of their auxiliary feathering pump motors had internal corrosion that may cause the stator magnets in the pump motor to fail and rotate into the path of... using certain Hamilton Sundstrand Corporation auxiliary pumps and motors (auxiliary feathering pumps...

  11. Hamilton's equations for a fluid membrane

    International Nuclear Information System (INIS)

    Capovilla, R; Guven, J; Rojas, E

    2005-01-01

    Consider a homogeneous fluid membrane described by the Helfrich-Canham energy, quadratic in the mean curvature of the membrane surface. The shape equation that determines equilibrium configurations is fourth order in derivatives and cubic in the mean curvature. We introduce a Hamiltonian formulation of this equation which dismantles it into a set of coupled first-order equations. This involves interpreting the Helfrich-Canham energy as an action; equilibrium surfaces are generated by the evolution of space curves. Two features complicate the implementation of a Hamiltonian framework. (i) The action involves second derivatives. This requires treating the velocity as a phase-space variable and the introduction of its conjugate momentum. The canonical Hamiltonian is constructed on this phase space. (ii) The action possesses a local symmetry-reparametrization invariance. The two labels we use to parametrize points on the surface are themselves physically irrelevant. This symmetry implies primary constraints, one for each label, that need to be implemented within the Hamiltonian. The two Lagrange multipliers associated with these constraints are identified as the components of the acceleration tangential to the surface. The conservation of the primary constraints implies two secondary constraints, fixing the tangential components of the momentum conjugate to the position. Hamilton's equations are derived and the appropriate initial conditions on the phase-space variables are identified. Finally, it is shown how the shape equation can be reconstructed from these equations

  12. On Montgomery's pair correlation conjecture to the zeros of Riedmann zeta function

    OpenAIRE

    Li, Pei

    2005-01-01

    In this thesis, we are interested in Montgomery's pair correlation conjecture which is about the distribution of.the spacings between consecutive zeros of the Riemann Zeta function. Our goal is to explain and study Montgomery's pair correlation conjecture and discuss its connection with the random matrix theory. In Chapter One, we will explain how to define the Ftiemann Zeta function by using the analytic continuation. After this, several classical properties of the Ftiemann Zeta function wil...

  13. Hamilton Place - Ontario Canadá

    Directory of Open Access Journals (Sweden)

    Garwood-Jones, T. P.

    1975-04-01

    Full Text Available Although comparatively modest as to its exterior, the interior of the theatre-auditorium Hamilton Place has been most successfully solved, both as regards design and acoustics. Construction techniques and elements have been utilized to achieve two different sections in one and the same hall with on one hand the capacity to be able to capture shades of the spoken word at theatrical functions and on the other to reproduce the sharpness and variety of orchestras and choirs. The following elements deserve special mention: the mobile wall which incorporates the orchestra into the hall by closing the proscenium arch; the two elevating platforms where the orchestra is placed; the vertical velvet surfaces, hung like banners which soften the repercussion of the sound; the mobile horizontal surfaces over the orchestra that direct and orient the sound. The most interesting construction techniques are: the subdivision of the building into different parts, each one with independent foundation so as to avoid the transmission of the sound from one section to the other; the texture of the brick walls that disperse the reflected sound; and the use of counterforts to create smaller more personal sections for varied use. The acoustic characteristics are improved by means of a sound installation, formed by small loudspeakers placed under each seat and by other bigger ones distributed in the walls that surround the hall. The building is completed by various service installations that are appropriate to this type of construction, as well as by a small theatre-studio for the rehearsals of the orchestra and the actors, while other functions are going on in the main hall.El teatro-auditorio Hamilton Place, aunque relativamente modesto por fuera, tiene soluciones muy afortunadas en el interior, tanto por su diseño como por su adecuación acústica. Se han utilizado elementos y técnicas constructivas destinadas a conseguir, en una única sala, dos espacios

  14. Convergent Difference Schemes for Hamilton-Jacobi equations

    KAUST Repository

    Duisembay, Serikbolsyn

    2018-01-01

    In this thesis, we consider second-order fully nonlinear partial differential equations of elliptic type. Our aim is to develop computational methods using convergent difference schemes for stationary Hamilton-Jacobi equations with Dirichlet

  15. Researcher Profile: An Interview with Axton Betz-Hamilton

    Directory of Open Access Journals (Sweden)

    Axton Betz-Hamilton

    2015-07-01

    Full Text Available Dr. Axton Betz-Hamilton teaches consumer studies courses at Eastern Illinois University, including Personal and Family Finance, Housing, and Consumer Issues. She conducts research on identity theft as well as financial abuse within families.

  16. Empty space-times with separable Hamilton-Jacobi equation

    International Nuclear Information System (INIS)

    Collinson, C.D.; Fugere, J.

    1977-01-01

    All empty space-times admitting a one-parameter group of motions and in which the Hamilton-Jacobi equation is (partially) separable are obtained. Several different cases of such empty space-times exist and the Riemann tensor is found to be either type D or N. The results presented here complete the search for empty space-times with separable Hamilton-Jacobi equation. (author)

  17. Mad Colonial Narrators in Anglo-Irish Literature: Lemuel Gulliver and Freddie Montgomery

    Directory of Open Access Journals (Sweden)

    Patricia Jones

    2018-03-01

    Full Text Available The following discussion highlights parallels between the narrators, Lemuel Gulliver of Jonathan Swift’s Gulliver’s Travels (1726 and Freddie Montgomery of John Banville’s The Book of Evidence (1989. The argument calls on post-colonialism, Foucaultian theory of “will to truth” and the narrative theory of Shlomith Rimmon-Kenan to emphasize similarities in the rendering of mental degeneration in Gulliver and Montgomery. The colonial-induced mental breakdown of both narrators can be said to unravel, not so much in the tale these narrators think they are relating, but instead between the lines of their stories in narratives which continually focus attention back onto themselves. Despite the 260 years separating these works, the madness of both Gulliver and Montgomery can be interpreted as a reluctance on their respective parts to shed established colonial identities once the colonial stage has receded.

  18. A generalization of Hamilton's rule--love others how much?

    Science.gov (United States)

    Alger, Ingela; Weibull, Jörgen W

    2012-04-21

    According to Hamilton's (1964a, b) rule, a costly action will be undertaken if its fitness cost to the actor falls short of the discounted benefit to the recipient, where the discount factor is Wright's index of relatedness between the two. We propose a generalization of this rule, and show that if evolution operates at the level of behavior rules, rather than directly at the level of actions, evolution will select behavior rules that induce a degree of cooperation that may differ from that predicted by Hamilton's rule as applied to actions. In social dilemmas there will be less (more) cooperation than under Hamilton's rule if the actions are strategic substitutes (complements). Our approach is based on natural selection, defined in terms of personal (direct) fitness, and applies to a wide range of pairwise interactions. Copyright © 2011 Elsevier Ltd. All rights reserved.

  19. Solution Hamilton-Jacobi equation for oscillator Caldirola-Kanai

    Directory of Open Access Journals (Sweden)

    LEONARDO PASTRANA ARTEAGA

    2016-12-01

    Full Text Available The method allows Hamilton-Jacobi explicitly determine the generating function from which is possible to derive a transformation that makes soluble Hamilton's equations. Using the separation of variables the partial differential equation of the first order called Hamilton-Jacobi equation is solved; as a particular case consider the oscillator Caldirola-Kanai (CK, which is characterized in that the mass presents a temporal evolution exponentially  . We demonstrate that the oscillator CK position presents an exponential decay in time similar to that obtained in the damped sub-critical oscillator, which reflects the dissipation of total mechanical energy. We found that in the limit that the damping factor  is small, the behavior is the same as an oscillator with simple harmonic motion, where the effects of energy dissipation is negligible.

  20. Quantum Hamilton mechanics: Hamilton equations of quantum motion, origin of quantum operators, and proof of quantization axiom

    International Nuclear Information System (INIS)

    Yang, C.-D.

    2006-01-01

    This paper gives a thorough investigation on formulating and solving quantum problems by extended analytical mechanics that extends canonical variables to complex domain. With this complex extension, we show that quantum mechanics becomes a part of analytical mechanics and hence can be treated integrally with classical mechanics. Complex canonical variables are governed by Hamilton equations of motion, which can be derived naturally from Schroedinger equation. Using complex canonical variables, a formal proof of the quantization axiom p → p = -ih∇, which is the kernel in constructing quantum-mechanical systems, becomes a one-line corollary of Hamilton mechanics. The derivation of quantum operators from Hamilton mechanics is coordinate independent and thus allows us to derive quantum operators directly under any coordinate system without transforming back to Cartesian coordinates. Besides deriving quantum operators, we also show that the various prominent quantum effects, such as quantization, tunneling, atomic shell structure, Aharonov-Bohm effect, and spin, all have the root in Hamilton mechanics and can be described entirely by Hamilton equations of motion

  1. The Magnus problem in Rodrigues-Hamilton parameters

    Science.gov (United States)

    Koshliakov, V. N.

    1984-04-01

    The formalism of Rodrigues-Hamilton parameters is applied to the Magnus problem related to the systematic drift of a gimbal-mounted astatic gyroscope due to the nutational vibration of the main axis of the rotor. It is shown that the use of the above formalism makes it possible to limit the analysis to a consideration of a linear system of differential equations written in perturbed values of Rodrigues-Hamilton parameters. A refined formula for the drift of the main axis of the gyroscope rotor is obtained, and an estimation is made of the effect of the truncation of higher-order terms.

  2. Numerical Solution of Hamilton-Jacobi Equations in High Dimension

    Science.gov (United States)

    2012-11-23

    high dimension FA9550-10-1-0029 Maurizio Falcone Dipartimento di Matematica SAPIENZA-Universita di Roma P. Aldo Moro, 2 00185 ROMA AH930...solution of Hamilton-Jacobi equations in high dimension AFOSR contract n. FA9550-10-1-0029 Maurizio Falcone Dipartimento di Matematica SAPIENZA

  3. Time-advance algorithms based on Hamilton's principle

    International Nuclear Information System (INIS)

    Lewis, H.R.; Kostelec, P.J.

    1993-01-01

    Time-advance algorithms based on Hamilton's variational principle are being developed for application to problems in plasma physics and other areas. Hamilton's principle was applied previously to derive a system of ordinary differential equations in time whose solution provides an approximation to the evolution of a plasma described by the Vlasov-Maxwell equations. However, the variational principle was not used to obtain an algorithm for solving the ordinary differential equations numerically. The present research addresses the numerical solution of systems of ordinary differential equations via Hamilton's principle. The basic idea is first to choose a class of functions for approximating the solution of the ordinary differential equations over a specific time interval. Then the parameters in the approximating function are determined by applying Hamilton's principle exactly within the class of approximating functions. For example, if an approximate solution is desired between time t and time t + Δ t, the class of approximating functions could be polynomials in time up to some degree. The issue of how to choose time-advance algorithms is very important for achieving efficient, physically meaningful computer simulations. The objective is to reliably simulate those characteristics of an evolving system that are scientifically most relevant. Preliminary numerical results are presented, including comparisons with other computational methods

  4. Proof of the 1-factorization and Hamilton decomposition conjectures

    CERN Document Server

    Csaba, Béla; Lo, Allan; Osthus, Deryk; Treglown, Andrew

    2016-01-01

    In this paper the authors prove the following results (via a unified approach) for all sufficiently large n: (i) [1-factorization conjecture] Suppose that n is even and D\\geq 2\\lceil n/4\\rceil -1. Then every D-regular graph G on n vertices has a decomposition into perfect matchings. Equivalently, \\chi'(G)=D. (ii) [Hamilton decomposition conjecture] Suppose that D \\ge \\lfloor n/2 \\rfloor . Then every D-regular graph G on n vertices has a decomposition into Hamilton cycles and at most one perfect matching. (iii) [Optimal packings of Hamilton cycles] Suppose that G is a graph on n vertices with minimum degree \\delta\\ge n/2. Then G contains at least {\\rm reg}_{\\rm even}(n,\\delta)/2 \\ge (n-2)/8 edge-disjoint Hamilton cycles. Here {\\rm reg}_{\\rm even}(n,\\delta) denotes the degree of the largest even-regular spanning subgraph one can guarantee in a graph on n vertices with minimum degree \\delta. (i) was first explicitly stated by Chetwynd and Hilton. (ii) and the special case \\delta= \\lceil n/2 \\rceil of (iii) answe...

  5. ACT Participation and Performance for Montgomery County Public Schools Students [2014]. Memorandum

    Science.gov (United States)

    Sanderson, Geoffrey T.

    2014-01-01

    The Montgomery County (Maryland) Public Schools (MCPS) Class of 2014 consistently outperformed graduates across Maryland and the nation on all sections of the ACT, according to the ACT, Inc. annual report that was released Wednesday, August 20, 2014. Thirty percent of the graduates in the MCPS Class of 2014 took the ACT exam. According to the ACT,…

  6. Online Opportunist: Mary Ellen Icaza--Montgomery County Public Libraries, Rockville, MD

    Science.gov (United States)

    Library Journal, 2004

    2004-01-01

    When Mary Ellen Icaza became Electronic Services Librarian at Montgomery County Public Libraries, she noticed that the readers' services information on the library web site was invisible, even to librarians. "And if staff can't find it," she says, "customers can't." She set out to help people find that material-and to turn a…

  7. Changes to the law on consent following Montgomery vs Lanarkshire Health Board.

    Science.gov (United States)

    Clearkin, Louis

    2016-06-01

    The Supreme Court's determination on Montgomery (AP) (Appellant) v Lanarkshire Health Board (Respondent) (Scotland) [2015] clarified UK law on consent. It is for the informed patient to determine which intervention, if any, they will undergo. All doctors must meet this standard and may need to reassess their practice to do so.

  8. Conceptualizing an Agenda for Social Responsibility and Public Policy at Montgomery College. A Briefing Paper. Revised

    Science.gov (United States)

    Scott, Michelle T.

    2007-01-01

    The purpose of this briefing paper is to conceptualize a social responsibility and public policy agenda for Montgomery College. The briefing paper provides (a) a well researched perspective to embed a College culture to actualize social responsibility and public policy as institutional practices; (b) examines some of the opportunities and…

  9. Official Reports of Enrollment as of September 30, 2013. Montgomery County Public Schools

    Science.gov (United States)

    Erickson, Marianne

    2013-01-01

    This document is a combination of two reports produced for Montgomery County Public Schools (MCPS) by the Department of Policy, Records, and Reporting: (1) Official Race/Ethnic Membership of Students as of September 30, 2013; and (2) Official Report of Enrollment by Grade and School as of September 30, 2013. Both reports provide student data for…

  10. 77 FR 28471 - Prevailing Rate Systems; Abolishment of Montgomery, PA, as a Nonappropriated Fund Federal Wage...

    Science.gov (United States)

    2012-05-15

    ... minimum of 26 NAF wage employees in the survey area, the local activity has the capability to host annual... County from the wage area definition. There are no longer NAF FWS employees working in Bucks County... Montgomery, PA, as a Nonappropriated Fund Federal Wage System Wage Area AGENCY: U.S. Office of Personnel...

  11. An Evaluation of the Employee Assistance Program in the Montgomery County Public School System.

    Science.gov (United States)

    Goldberg, Jo Ann

    The Montgomery County public school system presently provides assistance through the Employee Assistance Program (EAP) to troubled employees with problems which affect work performance. EAP's mandate is to provide crisis intervention, prereferral evaluation, information, referral, and follow-up services. From its inception to March, 1981, EAP…

  12. The Myth of "Rosa Parks the Tired." Teaching about Rosa Parks and the Montgomery Bus Boycott.

    Science.gov (United States)

    Kohl, Herbert

    1993-01-01

    Retells the story of Rosa Parks and the Montgomery (Alabama) bus boycott to reflect more accurately the cultural and historical background of the boycott and the conscious decision made by Mrs. Parks. Accurate examination of the story actually enhances a child's ability to identify with the issues and the protagonists. (SLD)

  13. The Politics of Children's Literature: The Story of Rosa Parks and the Montgomery Bus Boycott.

    Science.gov (United States)

    Kohl, Herbert

    1991-01-01

    As commonly told to and read by children, the story of Rosa Parks and the Montgomery bus boycott fails to indicate Mrs. Parks' activist role or the degree of community organization and participation in the boycott. Telling what actually occurred allows children identify with people who make justice happen. (SLD)

  14. A Hamilton-like vector for the special-relativistic Coulomb problem

    International Nuclear Information System (INIS)

    Munoz, Gerardo; Pavic, Ivana

    2006-01-01

    A relativistic point charge moving in a Coulomb potential does not admit a conserved Hamilton vector. Despite this fact, a Hamilton-like vector may be developed that proves useful in the derivation and analysis of the particle's orbit

  15. 78 FR 73750 - Proposed Amendment of Class E Airspace; Hamilton, OH

    Science.gov (United States)

    2013-12-09

    ...: Federal Aviation Administration (FAA), DOT. ACTION: Notice of proposed rulemaking (NPRM). SUMMARY: This action proposes to amend Class E airspace at Hamilton, OH. Decommissioning of the Hamilton nondirectional... the views and suggestions presented are particularly helpful in developing reasoned regulatory...

  16. El distribuidor de trafico de Hamilton-Inglaterra

    Directory of Open Access Journals (Sweden)

    Babtie Shaw and Morton, Ingenieros Consultores

    1969-06-01

    Full Text Available The first part of this article describes the initial stages in the construction of the complex traffic interchange at Hamilton, and gives details of all the special aspects which it involves. The second part deals with two of the three bridges at the Maryville interchange, and a detailed description is given of the most important features of these structures.La primera parte de este artículo muestra el trabajo de la primera etapa del complejo del distribuidor de tráfico de Hamilton, dándonos cuenta de las obras que engloba. La segunda parte trata de dos de los tres puentes que hay en el empalme de Maryville, describiéndolos y mostrando sus partes más importantes.

  17. Convergent Difference Schemes for Hamilton-Jacobi equations

    KAUST Repository

    Duisembay, Serikbolsyn

    2018-05-07

    In this thesis, we consider second-order fully nonlinear partial differential equations of elliptic type. Our aim is to develop computational methods using convergent difference schemes for stationary Hamilton-Jacobi equations with Dirichlet and Neumann type boundary conditions in arbitrary two-dimensional domains. First, we introduce the notion of viscosity solutions in both continuous and discontinuous frameworks. Next, we review Barles-Souganidis approach using monotone, consistent, and stable schemes. In particular, we show that these schemes converge locally uniformly to the unique viscosity solution of the first-order Hamilton-Jacobi equations under mild assumptions. To solve the scheme numerically, we use Euler map with some initial guess. This iterative method gives the viscosity solution as a limit. Moreover, we illustrate our numerical approach in several two-dimensional examples.

  18. Regularization of Hamilton-Lagrangian guiding center theories

    International Nuclear Information System (INIS)

    Correa-Restrepo, D.; Wimmel, H.K.

    1985-04-01

    The Hamilton-Lagrangian guiding-center (G.C.) theories of Littlejohn, Wimmel, and Pfirsch show a singularity for B-fields with non-vanishing parallel curl at a critical value of vsub(parallel), which complicates applications. The singularity is related to a sudden breakdown, at a critical vsub(parallel), of gyration in the exact particle mechanics. While the latter is a real effect, the G.C. singularity can be removed. To this end a regularization method is defined that preserves the Hamilton-Lagrangian structure and the conservation theorems. For demonstration this method is applied to the standard G.C. theory (without polarization drift). Liouville's theorem and G.C. kinetic equations are also derived in regularized form. The method could equally well be applied to the case with polarization drift and to relativistic G.C. theory. (orig.)

  19. Hamilton-Jacobi equations and brane associated Lagrangians

    International Nuclear Information System (INIS)

    Baker, L.M.; Fairlie, D.B.

    2001-01-01

    This article seeks to relate a recent proposal for the association of a covariant Field Theory with a string or brane Lagrangian to the Hamilton-Jacobi formalism for strings and branes. It turns out that since in this special case, the Hamiltonian depends only upon the momenta of the Jacobi fields and not the fields themselves, it is the same as a Lagrangian, subject to a constancy constraint. We find that the associated Lagrangians for strings or branes have a covariant description in terms of the square root of the same Lagrangian. If the Hamilton-Jacobi function is zero, rather than a constant, then it is in in one dimension lower, reminiscent of the 'holographic' idea. In the second part of the paper, we discuss properties of these Lagrangians, which lead to what we have called 'Universal Field Equations', characteristic of covariant equations of motion

  20. Lie-Hamilton systems on curved spaces: a geometrical approach

    Science.gov (United States)

    Herranz, Francisco J.; de Lucas, Javier; Tobolski, Mariusz

    2017-12-01

    A Lie-Hamilton system is a nonautonomous system of first-order ordinary differential equations describing the integral curves of a t-dependent vector field taking values in a finite-dimensional Lie algebra, a Vessiot-Guldberg Lie algebra, of Hamiltonian vector fields relative to a Poisson structure. Its general solution can be written as an autonomous function, the superposition rule, of a generic finite family of particular solutions and a set of constants. We pioneer the study of Lie-Hamilton systems on Riemannian spaces (sphere, Euclidean and hyperbolic plane), pseudo-Riemannian spaces (anti-de Sitter, de Sitter, and Minkowski spacetimes) as well as on semi-Riemannian spaces (Newtonian spacetimes). Their corresponding constants of motion and superposition rules are obtained explicitly in a geometric way. This work extends the (graded) contraction of Lie algebras to a contraction procedure for Lie algebras of vector fields, Hamiltonian functions, and related symplectic structures, invariants, and superposition rules.

  1. Higher order derivatives via Hamilton-Jacobi approach

    International Nuclear Information System (INIS)

    Bertin, M.C.; Pimentel, B.M.; Pompeia, P.J.

    2006-01-01

    In this work we will show how can be derived a general method for dealing with Lagrangians containing high order derivatives using the Hamilton-Jacobi Formalism for singular systems. By the expansion the configuration space of a n dimensional system we will be able to introduce first order actions and build the equations of motion of the system. We will work with the Generalized Electrodynamics of Podolsky as an example. (author)

  2. [Anna Hamilton (1864-1935), the excellence of nursing.

    Science.gov (United States)

    Diebolt, Évelyne

    2017-12-01

    A Frenchwoman, Anna Hamilton (1864-1935), daughter of a Franco-English couple, reads with passion the works of Florence Nightingale and takes an interest in nursing. In order to practice it, she first passes the equivalent of a bachelor’s degree in self-education and registers at the Marseille medical school. She wants to prepare a medical thesis on the nursing staff in the hospitals in Europe and is conducting an investigation throughout Europe. She passed her thesis on June 15, 1900 entitled “Considerations on hospital nurses”. This work is immediately published. That same year, she took up a post at the “Maison de santé protestante” in Bordeaux (MSP), founded in 1863. Without managerial staff, she is forced to recruit them abroad. She publishes a professional journal : “La Garde-Malade hospitalière” (1906-1914). Then the war turned the MSP into a military hospital, but the institution continued to receive local paying patients. She was given permission to call the school of nurses : Florence Nightingale School. Anna Hamilton is working with American women to create a medical and social service in Aisne. A graduate, Antoinette Hervey, then opened a medical-social service in Rouen, which would employ up to 30 visiting nurses. In 1916, the MSP received a donation from the domain of Bagatelle. The board of directors wants to sell it, but Anna Hamilton manages to finance a hospital-school thanks to families bereaved by the war and a subscription announced in the “Journal of Nursing”. Other establishments created by former students of the MSP opened : the School-hospital Ambroise Paré in Lille, a nursing home for nurses in Chambon-sur-Lignon in 1927 (the Edith-Seltzer foundation) and a sanatorium in Briançon. After a busy life, Anna Hamilton died of cancer in 1935 and is buried in Bordeaux.

  3. Nuclear power and the Hamilton-Jefferson debate

    International Nuclear Information System (INIS)

    Hacker, A.

    1980-01-01

    The basic sources of nuclear opposition derive from the philosophical arguments of Thomas Jefferson against Alexander Hamilton's vision of an industrial society with a strong central authority. Today's young people continue Jefferson's radical plea for the individual freedoms associated with personal ownership and limited government, but they accept the structure of the former while searching for the romanticism of the latter. The nuclear debate reflects this dichotomy and will continue even if the issues of waste disposal and safety are resolved

  4. Beyond WKB quantum corrections to Hamilton-Jacobi theory

    International Nuclear Information System (INIS)

    Jurisch, Alexander

    2007-01-01

    In this paper, we develop quantum mechanics of quasi-one-dimensional systems upon the framework of the quantum-mechanical Hamilton-Jacobi theory. We will show that the Schroedinger point of view and the Hamilton-Jacobi point of view are fully equivalent in their description of physical systems, but differ in their descriptive manner. As a main result of this, a wavefunction in Hamilton-Jacobi theory can be decomposed into travelling waves in any point in space, not only asymptotically. Using the quasi-linearization technique, we derive quantum correction functions in every order of h-bar. The quantum correction functions will remove the turning-point singularity that plagues the WKB-series expansion already in zeroth order and thus provide an extremely good approximation to the full solution of the Schroedinger equation. In the language of quantum action it is also possible to elegantly solve the connection problem without asymptotic approximations. The use of quantum action further allows us to derive an equation by which the Maslov index is directly calculable without any approximations. Stationary quantum trajectories will also be considered and thoroughly discussed

  5. An Appalachian portrait : black and white in Montgomery County, Virginia, before the Civil War

    OpenAIRE

    Grant, Charles L.

    1987-01-01

    Montgomery County, Virginia, is a southern Appalachian county founded in 1776. Throughout the county's antebellum history, as with most other regions of the South, four major population groups were visibly present. There were slaves, free blacks, white slaveowners, and white non-slaveowners. Little research has previously been conducted on the antebellum people of the Appalachian South. This work is a social history consisting of cross tabulations of data found in the county...

  6. Geology of the Birmingham, Gadsden, and Montgomery 10 x 20 NTMS Quadrangles, Alabama

    International Nuclear Information System (INIS)

    Copeland, C.W.; Beg, M.A.

    1979-04-01

    This document is a facsimile edition (with accompanying maps) of geologic reports on the Birmingham, Gadsden, and Montgomery 1 0 x 2 0 NTMS quadrangles prepared for SRL by the Geological Survey of Alabama. The purpose of these reports is to provide background geologic information to aid in the interpretation of NURE geochemical reconnaissance data. Each report includes descriptions of economic mineral localities as well as a mineral locality map and a geologic map

  7. Geology of the Birmingham, Gadsden, and Montgomery 10 x 20 NTMS quadrangles, Alabama

    International Nuclear Information System (INIS)

    Copeland, C.W.; Beg, M.A.

    1979-04-01

    This document is a facsimile edition (with accompanying maps) of geologic reports on the Birmingham, Gadsden, and Montgomery 1 0 x 2 0 NTMS quadrangles prepared for SRL by the Geological Survey of Alabama. Purpose of these reports is to provide background geologic information to aid in the interpretation of NURE geochemical reconnaissance data. Each report includes descriptions of economic mineral localities as well as a mineral locality map and a geologic map

  8. Hamilton's gradient estimate for the heat kernel on complete manifolds

    OpenAIRE

    Kotschwar, Brett

    2007-01-01

    In this paper we extend a gradient estimate of R. Hamilton for positive solutions to the heat equation on closed manifolds to bounded positive solutions on complete, non-compact manifolds with $Rc \\geq -Kg$. We accomplish this extension via a maximum principle of L. Karp and P. Li and a Bernstein-type estimate on the gradient of the solution. An application of our result, together with the bounds of P. Li and S.T. Yau, yields an estimate on the gradient of the heat kernel for complete manifol...

  9. Nuclear power and the Hamilton-Jefferson debate

    Energy Technology Data Exchange (ETDEWEB)

    Hacker, A.

    The basic sources of nuclear opposition derive from the philosophical arguments of Thomas Jefferson against Alexander Hamilton's vision of an industrial society with a strong central authority. Today's young people continue Jefferson's radical plea for the individual freedoms associated with personal ownership and limited government, but they accept the structure of the former while searching for the romanticism of the latter. The nuclear debate reflects this dichotomy and will continue even if the issues of waste disposal and safety are resolved. (DCK)

  10. Hamilton and Hardy for the 21st Century

    Science.gov (United States)

    Ogden, Trevor

    2016-01-01

    Hamilton and Hardy’s Industrial Toxicology is now 80 years old, and the new sixth edition links us with a pioneer era. This is an impressive book, but the usefulness of the hardback version as a reference book is unfortunately limited by its poor index. There is now an ebook version, and for the practitioner on the move this has the great advantages of searchability and portability. However, Wiley ebooks can apparently only be downloaded when first purchased, so their lifetime is limited to that of the device. The Kindle edition should avoid this shortcoming.

  11. Multimodal electromechanical model of piezoelectric transformers by Hamilton's principle.

    Science.gov (United States)

    Nadal, Clement; Pigache, Francois

    2009-11-01

    This work deals with a general energetic approach to establish an accurate electromechanical model of a piezoelectric transformer (PT). Hamilton's principle is used to obtain the equations of motion for free vibrations. The modal characteristics (mass, stiffness, primary and secondary electromechanical conversion factors) are also deduced. Then, to illustrate this general electromechanical method, the variational principle is applied to both homogeneous and nonhomogeneous Rosen-type PT models. A comparison of modal parameters, mechanical displacements, and electrical potentials are presented for both models. Finally, the validity of the electrodynamical model of nonhomogeneous Rosen-type PT is confirmed by a numerical comparison based on a finite elements method and an experimental identification.

  12. Elbow Room for Best Practice? Montgomery, Patients' values, and Balanced Decision-Making in Person-Centred Clinical Care.

    Science.gov (United States)

    Herring, Jonathan; Fulford, Kmw; Dunn, Michael; Handa, Ashoki

    2017-11-01

    The UK Supreme Court Montgomery judgment marks a decisive shift in the legal test of duty of care in the context of consent to treatment, from the perspective of the clinician (as represented by Bolam rules) to that of the patient. A majority of commentators on Montgomery have focused on the implications of the judgment for disclosure of risk. In this article, we set risk disclosure in context with three further elements of the judgment: benefits, options, and dialogue. These elements, we argue, taken together with risk disclosure, reflect the origins of the Montgomery ruling in a model of consent based on autonomy of patient choice through shared decision-making with their doctor. This model reflects recent developments in both law and medicine and is widely regarded (by the General Medical Council and others) as representing best practice in contemporary person-centred medicine. So understood, we suggest, the shift marked by Montgomery in the basis of duty of care is a shift in underpinning values: it is a shift from the clinician's interpretation about what would be best for patients to the values of (to what is significant or matters from the perspective of) the particular patient concerned in the decision in question. But the values of the particular patient do not thereby become paramount. The Montgomery test of duty of care requires the values of the particular patient to be balanced alongside the values of a reasonable person in the patient's position. We illustrate some of the practical challenges arising from the balance of considerations required by Montgomery with examples from surgical care. These examples show the extent to which Montgomery, in mirroring the realities of clinical decision-making, provides elbowroom for best practice in person-centred clinical care. © The Author 2017. Published by Oxford University Press; all rights reserved. For Permissions, please email: journals.permissions@oup.com.

  13. Hamilton's inclusive fitness maintains heritable altruism polymorphism through rb = c.

    Science.gov (United States)

    Wang, Changcao; Lu, Xin

    2018-02-20

    How can altruism evolve or be maintained in a selfish world? Hamilton's rule shows that the former process will occur when rb > c -the benefits to the recipients of an altruistic act b , weighted by the relatedness between the social partners r , exceed the costs to the altruists c -drives altruistic genotypes spreading against nonaltruistic ones. From this rule, we infer that altruistic genotypes will persist in a population by forming a stable heritable polymorphism with nonaltruistic genotypes if rb = c makes inclusive fitness of the two morphs equal. We test this prediction using the data of 12 years of study on a cooperatively breeding bird, the Tibetan ground tit Pseudopodoces humilis , where helping is performed by males only and kin-directed. Individual variation in ever acting as a helper was heritable ( h 2 = 0.47), and the resultant altruism polymorphism remained stable as indicated by low-level annual fluctuation of the percentage of helpers among all adult males (24-28%). Helpers' indirect fitness gains from increased lifetime reproductive success of related breeders statistically fully compensated for their lifetime direct fitness losses, suggesting that rb = c holds. While our work provides a fundamental support for Hamilton's idea, it highlights the equivalent inclusive fitness returns to altruists and nonaltruists mediated by rb = c as a theoretically and realistically important mechanism to maintain social polymorphism.

  14. Hamilton-Jacobi Approach to Pre-Big Bang Cosmology at Long-wavelengths

    CERN Document Server

    Saygili, K

    1999-01-01

    We apply the long-wavelength approximation to the low energy effective string action in the context of Hamilton-Jacobi theory. The Hamilton-Jacobi equation for the effective string action is explicitly invariant under scale factor duality. We present the leading order, general solution of the Hamilton-Jacobi equation. The Hamilton-Jacobi approach yields a solution consistent with the with the Lagrange formalism. The momentum constraints take an elegant, simple form. Furthermore this general solution reduces to the quasi-isotropic one, if the evolution of the gravitational field is neglected. Duality transformation for the general solution is written as a coordinate transformation in an abstract field space.

  15. Hamilton-Jacobi formalism to warm inflationary scenario

    Science.gov (United States)

    Sayar, K.; Mohammadi, A.; Akhtari, L.; Saaidi, Kh.

    2017-01-01

    The Hamilton-Jacobi formalism as a powerful method is being utilized to reconsider the warm inflationary scenario, where the scalar field as the main component driving inflation interacts with other fields. Separating the context into strong and weak dissipative regimes, the goal is followed for two popular functions of Γ . Applying slow-rolling approximation, the required perturbation parameters are extracted and, by comparing to the latest Planck data, the free parameters are restricted. The possibility of producing an acceptable inflation is studied where the result shows that for all cases the model could successfully suggest the amplitude of scalar perturbation, scalar spectral index, its running, and the tensor-to-scalar ratio.

  16. Hamilton-Jacobi approach to non-slow-roll inflation

    International Nuclear Information System (INIS)

    Kinney, W.H.

    1997-01-01

    I describe a general approach to characterizing cosmological inflation outside the standard slow-roll approximation, based on the Hamilton-Jacobi formulation of scalar field dynamics. The basic idea is to view the equation of state of the scalar field matter as the fundamental dynamical variable, as opposed to the field value or the expansion rate. I discuss how to formulate the equations of motion for scalar and tensor fluctuations in situations where the assumption of slow roll is not valid. I apply the general results to the simple case of inflation from an open-quotes invertedclose quotes polynomial potential, and to the more complicated case of hybrid inflation. copyright 1997 The American Physical Society

  17. Quality assurance for radon exposure chambers at the National Air and Radiation Environmental Laboratory, Montgomery, Alabama

    Energy Technology Data Exchange (ETDEWEB)

    Semler, M.O.; Sensintaffar, E.L. [National Air and Radiation Environmental Laboratory, Montgomery, AL (United States)

    1993-12-31

    The Office of Radiation and Indoor Air, U.S. Environmental Protection Agency (EPA), operates six radon exposure chambers in its two laboratories, the National Air and Radiation Environmental Laboratory (NAREL) in Montgomery, Alabama, and the Las Vegas Facility, Las Vegas, Nevada. These radon exposure chambers are used to calibrate and test portable radon measuring instruments, test commercial suppliers of radon measurement services through the Radon Measurement Proficiency Program, and expose passive measurement devices to known radon concentrations as part of a quality assurance plan for federal and state studies measuring indoor radon concentrations. Both laboratories participate in national and international intercomparisons for the measurement of radon and are presently working with the National Institute of Standards and Technology (NIST) to receive a certificate of traceability for radon measurements. NAREL has developed an estimate of the total error in its calibration of each chamber`s continuous monitors as part of an internal quality assurance program. This paper discusses the continuous monitors and their calibration for the three chambers located in Montgomery, Alabama, as well as the results of the authors intercomparisons and total error analysis.

  18. Inference-Based Similarity Search in Randomized Montgomery Domains for Privacy-Preserving Biometric Identification.

    Science.gov (United States)

    Wang, Yi; Wan, Jianwu; Guo, Jun; Cheung, Yiu-Ming; C Yuen, Pong

    2017-07-14

    Similarity search is essential to many important applications and often involves searching at scale on high-dimensional data based on their similarity to a query. In biometric applications, recent vulnerability studies have shown that adversarial machine learning can compromise biometric recognition systems by exploiting the biometric similarity information. Existing methods for biometric privacy protection are in general based on pairwise matching of secured biometric templates and have inherent limitations in search efficiency and scalability. In this paper, we propose an inference-based framework for privacy-preserving similarity search in Hamming space. Our approach builds on an obfuscated distance measure that can conceal Hamming distance in a dynamic interval. Such a mechanism enables us to systematically design statistically reliable methods for retrieving most likely candidates without knowing the exact distance values. We further propose to apply Montgomery multiplication for generating search indexes that can withstand adversarial similarity analysis, and show that information leakage in randomized Montgomery domains can be made negligibly small. Our experiments on public biometric datasets demonstrate that the inference-based approach can achieve a search accuracy close to the best performance possible with secure computation methods, but the associated cost is reduced by orders of magnitude compared to cryptographic primitives.

  19. Generally covariant Hamilton-Jacobi equation and rotated liquid sphere metrics

    International Nuclear Information System (INIS)

    Abdil'din, M.M.; Abdulgafarov, M.K.; Abishev, M.E.

    2005-01-01

    In the work Lense-Thirring problem on corrected Fock's first approximation metrics by Hamilton-Jacobi method considered. Generally covariant Hamilton-Jacobi equation had been sold by separation of variable method. Path equation of probe particle motion in rotated liquid sphere field is obtained. (author)

  20. Montgomery Blair Science, Mathematics and Computer Science Magnet Program: A Successful Model for Meeting the Needs of Highly Able STEM Learners

    Science.gov (United States)

    Stein, David; Ostrander, Peter; Lee, G. Maie

    2016-01-01

    The Magnet Program at Montgomery Blair High School is an application-based magnet program utilizing a curriculum focused on science, mathematics, and computer science catering to interested, talented, and eager to learn students in Montgomery County, Maryland. This article identifies and discusses some of the unique aspects of the Magnet Program…

  1. Seres Vivos. Nivel I. Basado en el curso de estudios de Ciencia de Montgomery County Public Schools. (Living Beings. Level 1. Based on the Montgomery County Public Schools Science Studies Program).

    Science.gov (United States)

    Senger, Graciela

    This curriculum unit, developed by the Montgomery County Public Schools, Maryland, was designed for use in the elementary level foreign language immersion program. It is geared toward the first grade science classroom. The unit includes instructional and performance objectives, necessary vocabulary lists, optional language structure sections,…

  2. La Materia. Nivel II. Basado en el curso de estudios de Ciencia de Montgomery County Public Schools. (Matter. Level II. Based on the Montgomery County Public Schools Science Studies Program).

    Science.gov (United States)

    Gerstman, M. Linda

    This curriculum unit is for use in an elementary school foreign language immersion program in Montgomery County, Maryland. The unit is geared toward the second grade science classroom. It includes instructional and performance objectives, vocabulary lists, optional language structure sections, illustrations, activities, evaluation suggestions, and…

  3. Effects of automated speed enforcement in Montgomery County, Maryland, on vehicle speeds, public opinion, and crashes.

    Science.gov (United States)

    Hu, Wen; McCartt, Anne T

    2016-09-01

    In May 2007, Montgomery County, Maryland, implemented an automated speed enforcement program, with cameras allowed on residential streets with speed limits of 35 mph or lower and in school zones. In 2009, the state speed camera law increased the enforcement threshold from 11 to 12 mph over the speed limit and restricted school zone enforcement hours. In 2012, the county began using a corridor approach, in which cameras were periodically moved along the length of a roadway segment. The long-term effects of the speed camera program on travel speeds, public attitudes, and crashes were evaluated. Changes in travel speeds at camera sites from 6 months before the program began to 7½ years after were compared with changes in speeds at control sites in the nearby Virginia counties of Fairfax and Arlington. A telephone survey of Montgomery County drivers was conducted in Fall 2014 to examine attitudes and experiences related to automated speed enforcement. Using data on crashes during 2004-2013, logistic regression models examined the program's effects on the likelihood that a crash involved an incapacitating or fatal injury on camera-eligible roads and on potential spillover roads in Montgomery County, using crashes in Fairfax County on similar roads as controls. About 7½ years after the program began, speed cameras were associated with a 10% reduction in mean speeds and a 62% reduction in the likelihood that a vehicle was traveling more than 10 mph above the speed limit at camera sites. When interviewed in Fall 2014, 95% of drivers were aware of the camera program, 62% favored it, and most had received a camera ticket or knew someone else who had. The overall effect of the camera program in its modified form, including both the law change and the corridor approach, was a 39% reduction in the likelihood that a crash resulted in an incapacitating or fatal injury. Speed cameras alone were associated with a 19% reduction in the likelihood that a crash resulted in an

  4. U.S. History and Modern World History Courses for English Speakers of Other Languages in Montgomery County Public Schools

    Science.gov (United States)

    Zhao, Huafang; Wade, Julie

    2014-01-01

    The Office of Shared Accountability (OSA) in Montgomery County (Maryland) Public Schools (MCPS) examined academic performance of English for Speakers of Other Languages (ESOL) students in U.S. History and Modern World History courses, as well as the course sequence in ESOL U.S. History and Modern World History. In MCPS, students who are not ESOL…

  5. A Portrait of School District Crisis Management: Leadership Choices in Montgomery County during the Sniper Shootings of October 2002

    Science.gov (United States)

    Porter, Brian Joseph

    2010-01-01

    The actions of two assailants who shot and killed 10 people and wounded three others, including a student, in the region around Washington, D.C., in October 2002, provides the backdrop for a qualitative study of the emergency response by school district leaders in Montgomery County, Maryland. The study explores and describes the experiences of the…

  6. Just the Right Mix: Identifying Potential Dropouts in Montgomery County Public Schools Using an Early Warning Indicators Approach

    Science.gov (United States)

    West, Thomas C.

    2013-01-01

    Each school year, roughly a thousand students drop out of Montgomery County (Maryland) Public Schools (MCPS). However, unlike other large, urban school districts where students who drop out skip school and are suspended often (Balfanz & Byrnes, 2010), students who drop out of MCPS are present in school; they just are not doing well…

  7. Land use mapping and change detection using ERTS imagery in Montgomery County, Alabama

    Science.gov (United States)

    Wilms, R. P.

    1973-01-01

    The feasibility of using remotely sensed data from ERTS-1 for mapping land use and detecting land use change was investigated. Land use information was gathered from 1964 air photo mosaics and from 1972 ERTS data. The 1964 data provided the basis for comparison with ERTS-1 imagery. From this comparison, urban sprawl was quite evident for the city of Montgomery. A significant trend from forestland to agricultural was also discovered. The development of main traffic arteries between 1964 and 1972 was a vital factor in the development of some of the urban centers. Even though certain problems in interpreting and correlating land use data from ERTS imagery were encountered, it has been demonstrated that remotely sensed data from ERTS is useful for inventorying land use and detecting land use change.

  8. Development and reliability of a structured interview guide for the Montgomery Asberg Depression Rating Scale (SIGMA).

    Science.gov (United States)

    Williams, Janet B W; Kobak, Kenneth A

    2008-01-01

    The Montgomery-Asberg Depression Rating Scale (MADRS) is often used in clinical trials to select patients and to assess treatment efficacy. The scale was originally published without suggested questions for clinicians to use in gathering the information necessary to rate the items. Structured and semi-structured interview guides have been found to improve reliability with other scales. To describe the development and test-retest reliability of a structured interview guide for the MADRS (SIGMA). A total of 162 test-retest interviews were conducted by 81 rater pairs. Each patient was interviewed twice, once by each rater conducting an independent interview. The intraclass correlation for total score between raters using the SIGMA was r=0.93, Preliability. Use of the SIGMA can result in high reliability of MADRS scores in evaluating patients with depression.

  9. Quantitative Compactness Estimates for Hamilton-Jacobi Equations

    Science.gov (United States)

    Ancona, Fabio; Cannarsa, Piermarco; Nguyen, Khai T.

    2016-02-01

    We study quantitative compactness estimates in {W^{1,1}_{loc}} for the map {S_t}, {t > 0} that is associated with the given initial data {u_0in Lip (R^N)} for the corresponding solution {S_t u_0} of a Hamilton-Jacobi equation u_t+Hbig(nabla_{x} ubig)=0, qquad t≥ 0,quad xinR^N, with a uniformly convex Hamiltonian {H=H(p)}. We provide upper and lower estimates of order {1/\\varepsilon^N} on the Kolmogorov {\\varepsilon}-entropy in {W^{1,1}} of the image through the map S t of sets of bounded, compactly supported initial data. Estimates of this type are inspired by a question posed by Lax (Course on Hyperbolic Systems of Conservation Laws. XXVII Scuola Estiva di Fisica Matematica, Ravello, 2002) within the context of conservation laws, and could provide a measure of the order of "resolution" of a numerical method implemented for this equation.

  10. Hamilton's equations for a fluid membrane

    Energy Technology Data Exchange (ETDEWEB)

    Capovilla, R [Departamento de Fisica, Centro de Investigacion y de Estudios Avanzados, Apdo. Postal 14-740, 07000 Mexico, DF (Mexico); Guven, J [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Apdo. Postal 70-543, 04510 Mexico, DF (Mexico); Rojas, E [Facultad de Fisica e Inteligencia Artificial, Universidad Veracruzana, 91000 Xalapa, Veracruz (Mexico)

    2005-10-14

    Consider a homogeneous fluid membrane described by the Helfrich-Canham energy, quadratic in the mean curvature of the membrane surface. The shape equation that determines equilibrium configurations is fourth order in derivatives and cubic in the mean curvature. We introduce a Hamiltonian formulation of this equation which dismantles it into a set of coupled first-order equations. This involves interpreting the Helfrich-Canham energy as an action; equilibrium surfaces are generated by the evolution of space curves. Two features complicate the implementation of a Hamiltonian framework. (i) The action involves second derivatives. This requires treating the velocity as a phase-space variable and the introduction of its conjugate momentum. The canonical Hamiltonian is constructed on this phase space. (ii) The action possesses a local symmetry-reparametrization invariance. The two labels we use to parametrize points on the surface are themselves physically irrelevant. This symmetry implies primary constraints, one for each label, that need to be implemented within the Hamiltonian. The two Lagrange multipliers associated with these constraints are identified as the components of the acceleration tangential to the surface. The conservation of the primary constraints implies two secondary constraints, fixing the tangential components of the momentum conjugate to the position. Hamilton's equations are derived and the appropriate initial conditions on the phase-space variables are identified. Finally, it is shown how the shape equation can be reconstructed from these equations.

  11. 78 FR 28838 - Hamilton Street Hydro, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2013-05-16

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 14507-000] Hamilton Street... Project would consist of the following: (1) An existing 10.5-foot-high rock fill gravity dam with a 655... a storage [[Page 28839

  12. An optimal L1-minimization algorithm for stationary Hamilton-Jacobi equations

    KAUST Repository

    Guermond, Jean-Luc; Popov, Bojan

    2009-01-01

    We describe an algorithm for solving steady one-dimensional convex-like Hamilton-Jacobi equations using a L1-minimization technique on piecewise linear approximations. For a large class of convex Hamiltonians, the algorithm is proven

  13. The community takes charge : story and success of Clean Air Hamilton

    International Nuclear Information System (INIS)

    McCarry, B.

    2004-01-01

    Clean Air Hamilton was established in 2001 to identify priority air quality issues, pollution sources, and evaluate impacts and solutions for air quality issues. Clean Air Hamilton also assesses the human health effects of ambient air exposures in Hamilton. A 1997 survey of Hamilton residents showed that most citizens were extremely concerned about health effects, black fallout, smog visibility, and odours. Clean Air Hamilton has established an air monitoring network which includes 19 member companies and 22 industrial sites. The objective is to determine recent contaminant trends in upwind/downwind air quality. The timeline for establishing the Hamilton air monitoring network was presented. The network, which serves as a model for Ontario and Canada, monitors the impact of vehicular and industrial emissions and establishes ten-year air quality trends for benzo(a)pyrene, sulphur, nitrogen dioxide, and ozone at industrial sites and the downtown core. Analysis of air quality trends shows that there has been improvement in levels of some locally-generated contaminants. The data has also been used for epidemiological studies to determine the health effects of industry on Hamiltonians. figs

  14. Hamilton Utilities Corporation annual report 2002 : people, performance, productivity : the business of public service

    International Nuclear Information System (INIS)

    2002-01-01

    A brief overview of the municipally-owned Hamilton Utilities Corporation was provided. When Ontario's electricity market opened to competition, it allowed wholesale and retail electricity marketers to operate on a competitive basis. This report describes how Hamilton Hydro, the largest subsidiary, successfully faced the challenges brought about by the open market. The strategy of growth as a multi-utility corporation progressed significantly. Major financial restructuring was completed, income level was maintained, as well as a strong balance sheet. The construction of Hamilton's first district energy system was effected by Hamilton Community Energy, another subsidiary. This project is expected to provide heat to 10 buildings in the downtown area, producing 3.5 megawatts of electricity for the City. The third subsidiary, FibreWired, applied its vast communications expertise to the health care sector. It offered Virtual Private Network (VPN) services to area hospitals and other health care providers in pharmaceutical and biotechnology. A major study was undertaken jointly with the City of Hamilton. It examined the feasibility of restructuring water and wastewater services into a municipally owned corporation under the umbrella of Hamilton Utilities Corporation. Various examples were provided throughout the report to better illustrate how corporate vision was translated into reality. tabs

  15. Hamilton-Jacobi theorems for regular reducible Hamiltonian systems on a cotangent bundle

    Science.gov (United States)

    Wang, Hong

    2017-09-01

    In this paper, some of formulations of Hamilton-Jacobi equations for Hamiltonian system and regular reduced Hamiltonian systems are given. At first, an important lemma is proved, and it is a modification for the corresponding result of Abraham and Marsden (1978), such that we can prove two types of geometric Hamilton-Jacobi theorem for a Hamiltonian system on the cotangent bundle of a configuration manifold, by using the symplectic form and dynamical vector field. Then these results are generalized to the regular reducible Hamiltonian system with symmetry and momentum map, by using the reduced symplectic form and the reduced dynamical vector field. The Hamilton-Jacobi theorems are proved and two types of Hamilton-Jacobi equations, for the regular point reduced Hamiltonian system and the regular orbit reduced Hamiltonian system, are obtained. As an application of the theoretical results, the regular point reducible Hamiltonian system on a Lie group is considered, and two types of Lie-Poisson Hamilton-Jacobi equation for the regular point reduced system are given. In particular, the Type I and Type II of Lie-Poisson Hamilton-Jacobi equations for the regular point reduced rigid body and heavy top systems are shown, respectively.

  16. Ground-water quality beneath an urban residential and commercial area, Montgomery, Alabama, 1999-2000

    Science.gov (United States)

    Robinson, James L.

    2002-01-01

    The Black Warrior River aquifer, which is composed of the Coker, Gordo, and Eutaw Formations, supplies more than 50 percent of the ground water used for public water supply in the Mobile River Basin. The city of Montgomery, Alabama, is partially built upon a recharge area for the Black Warrior River aquifer, and is one of many major population centers that depend on the Black Warrior River aquifer for public water supply. To represent the baseline ground-water quality in the Black Warrior River aquifer, water samples were collected from 30 wells located in a low-density residential or rural setting; 9 wells were completed in the Coker Formation, 9 wells in the Gordo Formation, and 12 wells in the Eutaw Formation. To describe the ground-water quality beneath Montgomery, Alabama, water samples also were collected from 30 wells located in residential and commercial areas of Montgomery, Alabama; 16 wells were completed in the Eutaw Formation, 8 wells in alluvial deposits, and 6 wells in terrace deposits. The alluvial and terrace deposits directly overlie the Eutaw Formation with little or no hydraulic separation. Ground-water samples collected from both the rural and urban wells were analyzed for physical properties, major ions, nutrients, metals, volatile organic compounds, and pesticides. Samples from the urban wells also were analyzed for bacteria, chlorofluorocarbons, dissolved gases, and sulfur hexafluoride. Ground-water quality beneath the urban area was compared to baseline water quality in the Black Warrior River aquifer.Compared to the rural wells, ground-water samples from urban wells contained greater concentrations or more frequent detections of chloride and nitrate, and the trace metals aluminium, chromium, cobalt, copper, nickel, and zinc. Pesticides and volatile organic compounds were detected more frequently and in greater concentrations in ground-water samples collected from urban wells than in ground-water samples from rural wells.The Spearman rho

  17. Map showing radon potential of rocks and soils in Montgomery County, Maryland

    Science.gov (United States)

    Gundersen, L.C.; Reimer, G.M.; Wiggs, C.R.; Rice, C.A.

    1988-01-01

    This report summarizes the radon potential of Montgomery County in the context of its geology. Radon is a naturally occurring gas produced by the radioactive decay of uranium. Radon produced by uraniferous rocks and soils may enter a house through porous building materials and through openings in walls and floors. Radon gases has a tendency to move from the higher pressure commonly existing in the soil to the lower pressure commonly existing in the house. The U.S. Environmental Protection Agency (U.S. EPA, 1986a) estimates that elevated levels of indoor radon may be associated with 5,000 to 20,000 of the 130,000 lung cancer deaths per year. They also estimate that 8 to 12 percent of the homes in the United States will have annual average indoor radon levels exceeding 4 picoCuries per liter of air (pCi/L). Above this level, the U.S. EPA recommends homeowners take remedial action. May factors control the amount of radon which may enter a home from the geologic environment. Soil drainage, permeability, and moisture content effect the amount of radon that can be released from rocks and soils (known as the emmanation) and may limit or increase how far it can migrate. Well drained, highly permeable soils facilitate the movement of radon. Soils with water content in the 8 to 15 percent range enhance the emmanation of radon (Lindmark, 1985). Daily and seasonal variations in soil and indoor radon can be caused by meteorologic factors such as barometric pressure, temperature, and wind (Clements and Wilkening, 1974; Schery and other, 1984). Construction practices also inhibit or promote entry of radon into the home (U.S. EPA, 1986b). In general, however, geology controls the source and distribution of radon (Akerblom and Wilson, 1982; Gundersen and others, 1987, 1988; Sextro and others, 1987; U.S. EPA, 1983; Peake, 1988; Peake and Hess, 1988). The following sections describe: 1) the methods used to measure radon and equivalent uranium (eU) in soil; 2) the radon potential

  18. Work Plan: Phase II Investigation at the Former CCC/USDA Grain Storage Facility in Montgomery City, Missouri

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, Lorraine M [Argonne National Lab. (ANL), Argonne, IL (United States)

    2012-05-01

    From September 1949 until September 1966, the Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA) leased property at the southeastern end of Montgomery City, Missouri, for the operation of a grain storage facility. During this time, commercial grain fumigants containing carbon tetrachloride were commonly used by the CCC/USDA and the private grain storage industry to preserve grain in their facilities.

  19. The secretion of areolar (Montgomery's glands from lactating women elicits selective, unconditional responses in neonates.

    Directory of Open Access Journals (Sweden)

    Sébastien Doucet

    2009-10-01

    Full Text Available The communicative meaning of human areolae for newborn infants was examined here in directly exposing 3-day old neonates to the secretion from the areolar glands of Montgomery donated by non related, non familiar lactating women.The effect of the areolar stimulus on the infants' behavior and autonomic nervous system was compared to that of seven reference stimuli originating either from human or non human mammalian sources, or from an arbitrarily-chosen artificial odorant. The odor of the native areolar secretion intensified more than all other stimuli the infants' inspiratory activity and appetitive oral responses. These responses appeared to develop independently from direct experience with the breast or milk.Areolar secretions from lactating women are especially salient to human newborns. Volatile compounds carried in these substrates are thus in a position to play a key role in establishing behavioral and physiological processes pertaining to milk transfer and production, and, hence, to survival and to the early engagement of attachment and bonding.

  20. Shape of Thyroid Cartilage Influences Outcome of Montgomery Medialization Thyroplasty: A Gender Issue.

    Science.gov (United States)

    Desuter, Gauthier; Henrard, Sylvie; Van Lith-Bijl, Julie T; Amory, Avigaëlle; Duprez, Thierry; van Benthem, Peter Paul; Sjögren, Elisabeth

    2017-03-01

    This study aimed to determine whether the shape of the thyroid cartilage and gender influence voice outcomes after a Montgomery thyroplasty implant system (MTIS). A retrospective cohort study was performed on 20 consecutive patients who underwent MTIS. Voice outcome variables were the relative decrease in Voice Handicap Index (%) and the absolute increase in maximum phonation time (MPT) (in seconds). Material variables were the angle between the thyroid cartilage laminae (α-angle), the size of the prosthesis, and a combination of both (the α-ratio). Continuous variables were analyzed using medians and were compared between groups using the Mann-Whitney U test. Factors associated with the outcome variables were assessed by multivariable linear regression. A Pearson coefficient was calculated between material variables. The absolute increase in MPT between the pre- and postoperative period was significantly different between men and women, with a median absolute increase of 11.0 seconds for men and of 1.3 seconds for women (P gender issue that needs to be further studied and eventually tackled. Copyright © 2017 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  1. Corporate preparedness for pandemic influenza: a survey of pharmaceutical and biotechnology companies in Montgomery County, Maryland.

    Science.gov (United States)

    Watkins, Rissah J; Barnett, Daniel J; Links, Jonathan M

    2008-09-01

    We conducted a survey of corporate preparedness for pandemic influenza among biotechnology and pharmaceutical companies in Montgomery County, Maryland, to determine the level of preparedness for this industry and geographic region. The survey, based on the HHS Business Pandemic Influenza Planning Checklist, established whether a company had a preparedness plan specific to pandemic influenza, the contents of its plan, or its reasons for a lack of a plan. A total of 50 companies participated in the survey. Of these, 40 did not have any type of preparedness plan, 3 were drafting plans, 6 had general preparedness plans that could be applied to an influenza pandemic, and only 1 company had a preparedness plan specifically designed to address pandemic influenza. Biotechnology and pharmaceutical companies in this geographic region are currently not well prepared for pandemic influenza. Public health officials should offer more help, possibly in the form of a model small business preparedness plan, and collaboration between companies should be encouraged to foster sharing of preparedness plans.

  2. Hamilton and Hardy: Mentoring and Friendship in the Service of Occupational Health.

    Science.gov (United States)

    Sullivan, Marianne

    This article explores the mentoring relationship between Alice Hamilton and Harriet Hardy, two female physician-researchers who had a tremendous impact on the development of the field of occupational health in the United States during the 20th century. The article relies on letters the women wrote to each other. Hamilton, the elder, supported and furthered Hardy's career by asking her to coauthor the second edition of a seminal occupational health text. After beginning this intellectual collaboration, Hamilton remained a mentor to Hardy, and a decades-long friendship ensued. The article explores their relationship within the historical, political, and social context in which the women worked and made remarkable contributions to public health.

  3. Obituary: George Hamilton Bowen Jr. (1925-2009)

    Science.gov (United States)

    Willson, Lee Anne; Struck, Curtis

    2011-12-01

    Our colleague and collaborator George Hamilton Bowen, Jr., passed away November 1, 2009 in Ames, Iowa. George was born June 20, 1925 in Tulsa, Oklahoma to George and Dorothy (Huntington) Bowen. He married Marjorie Brown June 19, 1948 in Redondo Beach, California; they had five children, with eight grandchildren and five great-grandchildren at the time of his death. George H. Bowen's third or perhaps his fourth career was in astronomy. He was drafted into the navy in 1944, at the end of his first year as a student at Caltech, and ended his war-time service as an electronic technician on the aircraft carrier Shangri-La. He later said "In just nine months, starting from scratch (Ohm's law!), we learned an amazing amount - not by memorization, of course, but by study and real understanding of the basic function of the most advanced AC circuits then being used for instrumentation, measurements, communications, control systems, and much more." He gained a confidence that he could quickly and accurately diagnose and solve technical problems that stood him well in future work. One accomplishment he took particular pride in was figuring out how the radar control used cams and gears to solve the trigonometry for accurate pointing. He also described how the captain was alarmed when weather conditions changed so that refraction no longer showed them distant, small boats around the curvature of Earth. After the war, George Bowen returned to undergraduate and eventually graduate study at Caltech, where he was recruited to the biophysics research group headed by future Nobel Laureate Max Delbrück. George often described his joy in working with these first-rate scientists and finding himself accepted as a part of the effort. He finished his BS with honors in 1949 and his PhD in 1953 with a thesis on "Kinetic Studies on the Mechanism of Photoreactivation of Bacteriophase T2 Inactivated by Ultraviolet Light" involving work with E Coli. This work was supported by grants from the U

  4. Game theory to characterize solutions of a discrete-time Hamilton-Jacobi equation

    International Nuclear Information System (INIS)

    Toledo, Porfirio

    2013-01-01

    We study the behavior of solutions of a discrete-time Hamilton-Jacobi equation in a minimax framework of game theory. The solutions of this problem represent the optimal payoff of a zero-sum game of two players, where the number of moves between the players converges to infinity. A real number, called the critical value, plays a central role in this work; this number is the asymptotic average action of optimal trajectories. The aim of this paper is to show the existence and characterization of solutions of a Hamilton-Jacobi equation for this kind of games

  5. Nonlinear H-infinity control, Hamiltonian systems and Hamilton-Jacobi equations

    CERN Document Server

    Aliyu, MDS

    2011-01-01

    A comprehensive overview of nonlinear Haeu control theory for both continuous-time and discrete-time systems, Nonlinear Haeu-Control, Hamiltonian Systems and Hamilton-Jacobi Equations covers topics as diverse as singular nonlinear Haeu-control, nonlinear Haeu -filtering, mixed H2/ Haeu-nonlinear control and filtering, nonlinear Haeu-almost-disturbance-decoupling, and algorithms for solving the ubiquitous Hamilton-Jacobi-Isaacs equations. The link between the subject and analytical mechanics as well as the theory of partial differential equations is also elegantly summarized in a single chapter

  6. New Li-Yau-Hamilton Inequalities for the Ricci Flow via the Space-Time Approach

    OpenAIRE

    Chow, Bennett; Knopf, Dan

    2002-01-01

    We generalize Hamilton's matrix Li-Yau-type Harnack estimate for the Ricci flow by considering the space of all LYH (Li-Yau-Hamilton) quadratics that arise as curvature tensors of space-time connections satisfying the Ricci flow with respect to the natural space-time degenerate metric. As a special case, we employ scaling arguments to derive a linear-type matrix LYH estimate. The new LYH quadratics obtained in this way are associated to the system of the Ricci flow coupled to a 1-form and a 2...

  7. Derivation of the Schrodinger Equation from the Hamilton-Jacobi Equation in Feynman's Path Integral Formulation of Quantum Mechanics

    Science.gov (United States)

    Field, J. H.

    2011-01-01

    It is shown how the time-dependent Schrodinger equation may be simply derived from the dynamical postulate of Feynman's path integral formulation of quantum mechanics and the Hamilton-Jacobi equation of classical mechanics. Schrodinger's own published derivations of quantum wave equations, the first of which was also based on the Hamilton-Jacobi…

  8. Hamilton-Jacobi equation and the breaking of the WKB approximation

    Energy Technology Data Exchange (ETDEWEB)

    Canfora, F. [Istituto Nazionale di Fisica Nucleare, GC di Salerno (Italy) and Dipartimento di Fisica E.R. Caianiello, Universita di Salerno, Via S. Allende, 84081 Baronissi (Salerno) (Italy)]. E-mail: canfora@sa.infn.it

    2005-03-17

    A simple method to deal with four-dimensional Hamilton-Jacobi equation for null hypersurfaces is introduced. This method allows to find simple geometrical conditions which give rise to the failure of the WKB approximation on curved spacetimes. The relation between such failure, extreme blackholes and the Cosmic Censor hypothesis is briefly discussed.

  9. Light Rail Transit in Hamilton: Health, Environmental and Economic Impact Analysis

    Science.gov (United States)

    Topalovic, P.; Carter, J.; Topalovic, M.; Krantzberg, G.

    2012-01-01

    Hamilton's historical roots as an electric, industrial and transportation-oriented city provide it with a high potential for rapid transit, especially when combined with its growing population, developing economy, redeveloping downtown core and its plans for sustainable growth. This paper explores the health, environmental, social and economic…

  10. 78 FR 22873 - Hamilton Street Hydro, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2013-04-17

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 14500-000] Hamilton Street... Hydroelectric Project would consist of the following: (1) An existing 14-foot-high concrete gravity dam with a 480-foot-long spillway; (2) an existing impoundment having a surface area of 50 acres and a storage...

  11. 78 FR 22872 - Hamilton Street Hydro, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Science.gov (United States)

    2013-04-17

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 14499-000] Hamilton Street... Project would consist of the following: (1) An existing 20-foot-high concrete gravity dam with a 690-foot-long spillway; (2) an existing impoundment having a surface area of 300 acres and a storage capacity of...

  12. 77 FR 52058 - Notice of Inventory Completion: Longyear Museum of Anthropology, Colgate University, Hamilton, NY

    Science.gov (United States)

    2012-08-28

    ... Inventory Completion: Longyear Museum of Anthropology, Colgate University, Hamilton, NY AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Longyear Museum of Anthropology has completed an... cultural affiliation with the human remains should contact the Longyear Museum of Anthropology at the...

  13. 76 FR 48178 - Notice of Inventory Completion: Longyear Museum of Anthropology, Colgate University, Hamilton, NY

    Science.gov (United States)

    2011-08-08

    ...: Longyear Museum of Anthropology, Colgate University, Hamilton, NY AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Longyear Museum of Anthropology has completed an inventory of a human remain... human remain should contact the Longyear Museum of Anthropology at the address below by September 7...

  14. L∞-error estimates of a finite element method for the Hamilton-Jacobi-Bellman equations

    International Nuclear Information System (INIS)

    Bouldbrachene, M.

    1994-11-01

    We study the finite element approximation for the solution of the Hamilton-Jacobi-Bellman equations involving a system of quasi-variational inequalities (QVI). We also give the optimal L ∞ -error estimates, using the concepts of subsolutions and discrete regularity. (author). 7 refs

  15. Perceptions of Quality Life in Hamilton's Neighbourhood Hubs: A Qualitative Analysis

    Science.gov (United States)

    Eby, Jeanette; Kitchen, Peter; Williams, Allison

    2012-01-01

    This paper examines perceptions of quality of life in Hamilton, Ontario, Canada from the perspective of residents and key community stakeholders. A series of eight focus groups were conducted. Six sessions were held with residents of neighbourhood "hubs", areas characterized by high levels of poverty. The following themes were…

  16. Octavia Butler and Virginia Hamilton: Black Women Writers and Science Fiction.

    Science.gov (United States)

    Hampton, Gregory Jerome; Brooks, Wanda M.

    2003-01-01

    Notes that African American literature has always had science fiction elements in its focus on narratives of the alienated and marginalized "other." Contends that Octavia Butler and Virginia Hamilton are two African American writers of science fiction who examine the connections between the stories of a culture and the genre of science…

  17. Air Quality in Hamilton: Who Is Concerned? Perceptions from Three Neighbourhoods

    Science.gov (United States)

    Simone, Dylan; Eyles, John; Newbold, K. Bruce; Kitchen, Peter; Williams, Allison

    2012-01-01

    This study investigates the factors influencing perceptions of air quality in the industrial city of Hamilton, Canada. The research employs data collected via a telephone survey of 1,002 adult residents in three neighbourhoods. Perceptions in the neighbourhoods were examined by individual socio-demographic factors (age, gender, marital and…

  18. An optimal L1-minimization algorithm for stationary Hamilton-Jacobi equations

    KAUST Repository

    Guermond, Jean-Luc

    2009-01-01

    We describe an algorithm for solving steady one-dimensional convex-like Hamilton-Jacobi equations using a L1-minimization technique on piecewise linear approximations. For a large class of convex Hamiltonians, the algorithm is proven to be convergent and of optimal complexity whenever the viscosity solution is q-semiconcave. Numerical results are presented to illustrate the performance of the method.

  19. 76 FR 25534 - Airworthiness Directives; Hamilton Sundstrand Propellers Model 247F Propellers

    Science.gov (United States)

    2011-05-05

    ... 5 p.m., Monday through Friday, except Federal holidays. The AD docket contains this AD, the... through FR2279 inclusive, FR 2398, FR2449 to FR2958 inclusive, FR20010710 to FR20010722 inclusive, and FR20010723RT to FR20020127RT inclusive, installed. Propeller blades reworked to Hamilton Sundstrand Service...

  20. Durand Neighbourhood Heritage Inventory: Toward a Digital Citywide Survey Approach to Heritage Planning in Hamilton

    Science.gov (United States)

    Angel, V.; Garvey, A.; Sydor, M.

    2017-08-01

    In the face of changing economies and patterns of development, the definition of heritage is diversifying, and the role of inventories in local heritage planning is coming to the fore. The Durand neighbourhood is a layered and complex area located in inner-city Hamilton, Ontario, Canada, and the second subject area in a set of pilot inventory studies to develop a new city-wide inventory strategy for the City of Hamilton,. This paper presents an innovative digital workflow developed to undertake the Durand Built Heritage Inventory project. An online database was developed to be at the centre of all processes, including digital documentation, record management, analysis and variable outputs. Digital tools were employed for survey work in the field and analytical work in the office, resulting in a GIS-based dataset that can be integrated into Hamilton's larger municipal planning system. Together with digital mapping and digitized historical resources, the Durand database has been leveraged to produce both digital and static outputs to shape recommendations for the protection of Hamilton's heritage resources.

  1. Mobile Air Monitoring: Measuring Change in Air Quality in the City of Hamilton, 2005-2010

    Science.gov (United States)

    Adams, Matthew D.; DeLuca, Patrick F.; Corr, Denis; Kanaroglou, Pavlos S.

    2012-01-01

    This paper examines the change in air pollutant concentrations between 2005 and 2010 occurring in the City of Hamilton, Ontario, Canada. After analysis of stationary air pollutant concentration data, we analyze mobile air pollutant concentration data. Air pollutants included in the analysis are CO, PM[subscript 2.5], SO[subscript 2], NO,…

  2. Hamilton-Jacobi formalism for Podolsky's electromagnetic theory on the null-plane

    Science.gov (United States)

    Bertin, M. C.; Pimentel, B. M.; Valcárcel, C. E.; Zambrano, G. E. R.

    2017-08-01

    We develop the Hamilton-Jacobi formalism for Podolsky's electromagnetic theory on the null-plane. The main goal is to build the complete set of Hamiltonian generators of the system as well as to study the canonical and gauge transformations of the theory.

  3. 'From Man to Bacteria': W.D. Hamilton, the theory of inclusive fitness, and the post-war social order.

    Science.gov (United States)

    Swenson, Sarah A

    2015-02-01

    W.D. Hamilton's theory of inclusive fitness aimed to define the evolved limits of altruism with mathematical precision. Although it was meant to apply universally, it has been almost irretrievably entwined with the particular case of social insects that featured in his famous 1964 papers. The assumption that social insects were central to Hamilton's early work contradicts material in his rich personal archive. In fact, careful study of Hamilton's notes, letters, diaries, and early essays indicates the extent to which he had humans in mind when he decided altruism was a topic worthy of biological inquiry. For this reason, this article reconsiders the role of extra-scientific factors in Hamilton's early theorizing. In doing so, it offers an alternative perspective as to why Hamilton saw self-sacrifice to be an important subject. Although the traditional narrative prioritizes his distaste for benefit-of-the-species explanations as a motivating factor behind his foundational work, I argue that greater attention ought to be given to Hamilton's hope that science could be used to address social ills. By reconsidering the meaning Hamilton intended inclusive fitness to have, we see that while he was no political ideologue, the socio-political relevance of his theory was nevertheless integral to its development. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. A generalization of Hamilton's rule for the evolution of microbial cooperation.

    Science.gov (United States)

    Smith, Jeff; Van Dyken, J David; Zee, Peter C

    2010-06-25

    Hamilton's rule states that cooperation will evolve if the fitness cost to actors is less than the benefit to recipients multiplied by their genetic relatedness. This rule makes many simplifying assumptions, however, and does not accurately describe social evolution in organisms such as microbes where selection is both strong and nonadditive. We derived a generalization of Hamilton's rule and measured its parameters in Myxococcus xanthus bacteria. Nonadditivity made cooperative sporulation remarkably resistant to exploitation by cheater strains. Selection was driven by higher-order moments of population structure, not relatedness. These results provide an empirically testable cooperation principle applicable to both microbes and multicellular organisms and show how nonlinear interactions among cells insulate bacteria against cheaters.

  5. Perturbation to Unified Symmetry and Adiabatic Invariants for Relativistic Hamilton Systems

    International Nuclear Information System (INIS)

    Zhang Mingjiang; Fang Jianhui; Lu Kai; Pang Ting; Lin Peng

    2009-01-01

    Based on the concept of adiabatic invariant, the perturbation to unified symmetry and adiabatic invariants for relativistic Hamilton systems are studied. The definition of the perturbation to unified symmetry for the system is presented, and the criterion of the perturbation to unified symmetry is given. Meanwhile, the Noether adiabatic invariants, the generalized Hojman adiabatic invariants, and the Mei adiabatic invariants for the perturbed system are obtained. (general)

  6. Respiratory Medicine at McMaster University, Hamilton, Ontario: 1968 to 2013

    Directory of Open Access Journals (Sweden)

    Norman L Jones

    2014-01-01

    Full Text Available The medical school at McMaster University (Hamilton, Ontario was conceived in 1965, and admitted the first class in 1969. John Evans became the founding Dean and he invited EJ Moran Campbell to be the first Chairman of the Department of Medicine. Moran Campbell, already a world figure in respiratory medicine and physiology, arrived at McMaster in September 1968, and he invited Norman Jones to be Coordinator of the Respiratory Programme.

  7. Respiratory Medicine at McMaster University, Hamilton, Ontario: 1968 To 2013

    Directory of Open Access Journals (Sweden)

    Norman L Jones

    2014-01-01

    Full Text Available The medical school at McMaster University (Hamilton, Ontario was conceived in 1965 and admitted the first class in 1969. John Evans became the founding Dean and he invited Moran Campbell to be the first Chairman of the Department of Medicine. Moran Campbell, already a world figure in respiratory medicine and physiology, arrived at McMaster in September 1968, and he invited Norman Jones to be Coordinator of the Respiratory Programme.

  8. Existence of solutions for Hamiltonian field theories by the Hamilton-Jacobi technique

    International Nuclear Information System (INIS)

    Bruno, Danilo

    2011-01-01

    The paper is devoted to prove the existence of a local solution of the Hamilton-Jacobi equation in field theory, whence the general solution of the field equations can be obtained. The solution is adapted to the choice of the submanifold where the initial data of the field equations are assigned. Finally, a technique to obtain the general solution of the field equations, starting from the given initial manifold, is deduced.

  9. Regional climate change trends and uncertainty analysis using extreme indices: A case study of Hamilton, Canada

    OpenAIRE

    Razavi, Tara; Switzman, Harris; Arain, Altaf; Coulibaly, Paulin

    2016-01-01

    This study aims to provide a deeper understanding of the level of uncertainty associated with the development of extreme weather frequency and intensity indices at the local scale. Several different global climate models, downscaling methods, and emission scenarios were used to develop extreme temperature and precipitation indices at the local scale in the Hamilton region, Ontario, Canada. Uncertainty associated with historical and future trends in extreme indices and future climate projectio...

  10. Hamilton-Jacobi-Bellman approach for the climbing problem for heavy launchers

    OpenAIRE

    Bokanowski , Olivier; Cristiani , Emiliano; Laurent-Varin , Julien; Zidani , Hasnaa

    2012-01-01

    International audience; In this paper we investigate the Hamilton-Jacobi-Bellman (HJB) approach for solving a complex real-world optimal control problem in high dimension. We consider the climbing problem for the European launcher Ariane V: The launcher has to reach the Geostationary Transfer Orbit with minimal propellant consumption under state/control constraints. In order to circumvent the well-known curse of dimensionality, we reduce the number of variables in the model exploiting the spe...

  11. Variational energy principle for compressible, baroclinic flow. 2: Free-energy form of Hamilton's principle

    Science.gov (United States)

    Schmid, L. A.

    1977-01-01

    The first and second variations are calculated for the irreducible form of Hamilton's Principle that involves the minimum number of dependent variables necessary to describe the kinetmatics and thermodynamics of inviscid, compressible, baroclinic flow in a specified gravitational field. The form of the second variation shows that, in the neighborhood of a stationary point that corresponds to physically stable flow, the action integral is a complex saddle surface in parameter space. There exists a form of Hamilton's Principle for which a direct solution of a flow problem is possible. This second form is related to the first by a Friedrichs transformation of the thermodynamic variables. This introduces an extra dependent variable, but the first and second variations are shown to have direct physical significance, namely they are equal to the free energy of fluctuations about the equilibrium flow that satisfies the equations of motion. If this equilibrium flow is physically stable, and if a very weak second order integral constraint on the correlation between the fluctuations of otherwise independent variables is satisfied, then the second variation of the action integral for this free energy form of Hamilton's Principle is positive-definite, so the action integral is a minimum, and can serve as the basis for a direct trail and error solution. The second order integral constraint states that the unavailable energy must be maximum at equilibrium, i.e. the fluctuations must be so correlated as to produce a second order decrease in the total unavailable energy.

  12. Comparative validation of proxy-based montgomery-asberg depression rating scale and cornell scale for depression in dementia in nursing home residents with dementia

    NARCIS (Netherlands)

    Leontjevas, R.; Gerritsen, D.L.; Vernooij-Dassen, M.F.J.; Smalbrugge, M.; Koopmans, R.T.C.M.

    2012-01-01

    Objective: To 1) compare the accuracy of the Montgomery-̊Asberg Depression Rating Scale (MADRS) and the Cornell Scale for Depression in Dementia (CSDD) in nursing home residents with dementia when professional caregivers are the only available source of information and 2) explore different methods

  13. "Cancer-Related Fatigue: A Systematic and Meta-Analytic Review of Nonpharmacological Therapies for Cancer Patients:" Correction to Kangas, Bovbjerg, and Montgomery (2008)

    Science.gov (United States)

    Kangas, Maria; Bovbjerg, Dana H.; Montgomery, Guy H.

    2009-01-01

    Reports an error in "Cancer-related fatigue: A systematic and meta-analytic review of non-pharmacological therapies for cancer patients" by Maria Kangas, Dana H. Bovbjerg and Guy H. Montgomery (Psychological Bulletin, 2008[Sep], Vol 134[5], 700-741). The URL to the Supplemental Materials for the article is listed incorrectly in two places in the…

  14. 2013 Advanced Placement Exam Participation and Performance for Students in Montgomery County Public Schools and Public School Students in the State of Maryland and the Nation. Memorandum

    Science.gov (United States)

    Sanderson, Geoffrey T.

    2013-01-01

    This memorandum provides data on the participation and performance of Advanced Placement (AP) exams taken by students in the Montgomery County (Maryland) Public Schools (MCPS) in the 2012-2013 school year as compared with those by public school students in Maryland and the nation. Generally, the number of AP exams taken by MCPS students in 2013…

  15. From the Snell-Descartes refraction law, to the Hamilton equations in the phase space of geometrical optics

    International Nuclear Information System (INIS)

    Lopez Moreno, E.; Wolf, K.B.

    1989-01-01

    Starting from the Snell-Descartes' refraction law, we obtain in a brief and direct way the Hamilton equations of Geometrical Optics. We show the global structure of phase space and compare it with that used in paraxial optics. (Author)

  16. Estimated rates of groundwater recharge to the Chicot, Evangeline and Jasper aquifers by using environmental tracers in Montgomery and adjacent counties, Texas, 2008 and 2011

    Science.gov (United States)

    Oden, Timothy D.; Truini, Margot

    2013-01-01

    Montgomery County is in the northern part of the Houston, Texas, metropolitan area, the fourth most populous metropolitan area in the United States. As populations have increased since the 1980s, groundwater has become an important resource for public-water supply and industry in the rapidly growing area of Montgomery County. Groundwater availability from the Gulf Coast aquifer system is a primary concern for water managers and community planners in Montgomery County and requires a better understanding of the rate of recharge to the system. The Gulf Coast aquifer system in Montgomery County consists of the Chicot, Evangeline, and Jasper aquifers, the Burkeville confining unit, and underlying Catahoula confining system. The individual sand and clay sequences of the aquifers composing the Gulf Coast aquifer system are not laterally or vertically continuous on a regional scale; however, on a local scale, individual sand and clay lenses can extend over several miles. The U.S. Geological Survey, in cooperation with the Lone Star Groundwater Conservation District, collected groundwater-quality samples from selected wells within or near Montgomery County in 2008 and analyzed these samples for concentrations of chlorofluorocarbons (CFCs), sulfur hexafluoride (SF6), tritium (3H), helium-3/tritium (3He/3H), helium-4 (4He), and dissolved gases (DG) that include argon, carbon dioxide, methane, nitrogen and oxygen. Groundwater ages, or apparent age, representing residence times since time of recharge, were determined by using the assumption of a piston-flow transport model. Most of the environmental tracer data indicated the groundwater was recharged prior to the 1950s, limiting the usefulness of CFCs, SF6, and 3H concentrations as tracers. In many cases, no tracer was usable at a well for the purpose of estimating an apparent age. Wells not usable for estimating an apparent age were resampled in 2011 and analyzed for concentrations of major ions and carbon-14 (14C). At six of

  17. Hamilton's Optics

    Indian Academy of Sciences (India)

    IAS Admin

    ing to the two well-known laws. These lead to ... through a telescope – the theory is rather uninspiring. ... Figure 1b. The law of reflection implies that the path length is `stationary' . ..... imum principles, governing two different kinds of sys-.

  18. Non-destructive examination of a time capsule recovered from the Gore Park excavations, Hamilton, Ontario

    International Nuclear Information System (INIS)

    MacDonald, B.L.; Vanderstelt, J.

    2015-01-01

    Non-destructive analytical techniques are becoming increasingly important for the study of objects of cultural heritage interest. We present a study that applied two techniques: x-ray fluorescence (XRF) and neutron radiography, for the investigation of a time capsule recovered from an urban construction site in Gore Park, Hamilton. XRF analysis revealed the composition of the artifact, while n-radiography showed that its contents remained intact after being interred for 91 years. Results of this study demonstrate the value of non-destructive techniques for the analysis and preservation of cultural heritage. (author)

  19. On the Connection between the Hamilton-Jacobi-Bellman and the Fokker-Planck Control Frameworks

    KAUST Repository

    Annunziato, Mario

    2014-09-01

    In the framework of stochastic processes, the connection between the dynamic programming scheme given by the Hamilton-Jacobi-Bellman equation and a recently proposed control approach based on the Fokker-Planck equation is discussed. Under appropriate assumptions it is shown that the two strategies are equivalent in the case of expected cost functionals, while the FokkerPlanck formalism allows considering a larger class of objectives. To illustrate the connection between the two control strategies, the cases of an Itō stochastic process and of a piecewise-deterministic process are considered.

  20. Results of the radiological survey at Diebold Safe Company, 1550 Grand Boulevard, Hamilton, Ohio (HO001)

    International Nuclear Information System (INIS)

    Foley, R.D.; Floyd, L.M.

    1990-02-01

    At the request of the US Department of Energy (DOE), a group from Oak Ridge National Laboratory conducted investigative radiological surveys at Diebold Safe Company, 1550 Grand Boulevard, Hamilton, Ohio in 1988 and 1989. The purpose of the surveys was to determine whether the property was contaminated with radioactive residues, principally 238 U. The surveys included gamma scans; direct and transferable measurements of alpha, beta, and gamma radiation levels; and dust, debris, air, and soil sampling for radionuclide analyses. 6 refs., 6 figs., 5 tabs

  1. Code Red: Explaining Average Age of Death in the City of Hamilton

    Directory of Open Access Journals (Sweden)

    Patrick F. DeLuca

    2015-11-01

    Full Text Available The aim of this study is to identify the underlying factors that explain the average age of death in the City of Hamilton, Ontario, Canada, as identified in the Code Red Series of articles that were published in the city's local newspaper in 2010. Using a combination of data from the Canadian Census, the Government of Ontario and the Canadian Institute for Health Information, factor analysis was performed yielding three factors relating to poverty, working class, and health and aging. In a regression analysis these factors account for 42% of the total variability in the average ages of death observed at the census tract level of geography within the city.

  2. A case study: the initiative to improve RN scheduling at Hamilton Health Sciences.

    Science.gov (United States)

    Wallace, Laurel-Anne; Pierson, Sharon

    2008-01-01

    In 2003, Hamilton Health Sciences embarked on an initiative to improve and standardize nursing schedules and scheduling practices. The scheduling project was one of several initiatives undertaken by a corporate-wide Nursing Resource Group established to enhance the work environment and patient care and to ensure appropriate utilization of nursing resources across the organization's five hospitals. This article focuses on major activities undertaken in the scheduling initiative. The step-by-step approach described, plus examples of the scheduling resources developed and samples of extended-tour schedules, will all provide insight, potential strategies and practical help for nursing administrators, human resources (HR) personnel and others interested in improving nurse scheduling.

  3. Phase I Investigations at the Former CCC/USDA Grain Storage Facility in Montgomery City, Missouri, in 2010-2011

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, Lorraine M. [Argonne National Lab. (ANL), Argonne, IL (United States). Environmental Science Division. Applied Geoscience and Environmental Restoration Program

    2012-11-01

    This report presents the technical findings of Phase I of Argonne’s studies. The Phase I field investigation was initiated on October 18, 2010. The work was conducted in accord with (1) the final site-specific Phase I Work Plan for Montgomery City (Argonne 2010; approved by the MDNR [2010]); (2) applicable Missouri regulations; and (3) the standard operating procedures, quality assurance/quality control (QA/QC) measures, and general health and safety policies outlined in the Master Work Plan (Argonne 2002) for operations in Kansas, which was reviewed by the MDNR and accepted for current use. A draft master plan specific to work in Missouri and a set of draft standard operating procedures are in review with the MDNR. The site-specific Work Plan for Montgomery City (Argonne 2010) (1) summarizes the pre-existing knowledge base for the Montgomery City investigation site compiled by Argonne and (2) describes the site-specific technical objectives and the intended scope of work developed for the first phase of the investigation. Three primary technical objectives were identified for the Phase I studies, as follows: 1. Update the presently identified inventory and status of private and public drinking water wells in the immediate vicinity of the former CCC/USDA grain storage facility, and sample the identified wells for volatile organic compounds (VOCs) and geochemical analyses. In conjunction with this effort, determine the present sources(s) of drinking water for all residents in an approximate 0.5-mi radius of the former CCC/USDA facility. 2. Investigate for possible evidence of a soil source of carbon tetrachloride contamination in the unconsolidated sediments beneath the former CCC/USDA facility that might affect the underlying bedrock aquifer units. 3. Obtain preliminary information on the site-specific lithologic and hydrologic characteristics of the unconsolidated sediments overlying bedrock at the former CCC/USDA grain storage location. Section 2 of this report

  4. From Bolam-Bolitho to Modified-Montgomery - A Paradigm Shift in the Legal Standard of Determining Medical Negligence in Singapore.

    Science.gov (United States)

    Neo, Han Yee

    2017-09-01

    In a recent landmark litigation, the Singapore Court of Appeal introduced a new legal standard for determining medical negligence with regards to information disclosure - the Modified-Montgomery test. This new test fundamentally shifts the legal position concerning the standard of care expected of a doctor when he dispenses medical advice. Previously, a doctor is expected to disclose what a "reasonable physician" would tell his patient. Now, a doctor must disclose "all material risks" that a "reasonable patient" would want to know under his unique circumstances. Patient-centred communication is no longer an aspirational ideal but has become a legal mandate. Manpower, administrative, logistic and medical educational reforms should start now, so as to support the average physician transit from the era of the Bolam-Bolitho, to that of the Modified-Montgomery.

  5. DURAND NEIGHBOURHOOD HERITAGE INVENTORY: TOWARD A DIGITAL CITYWIDE SURVEY APPROACH TO HERITAGE PLANNING IN HAMILTON

    Directory of Open Access Journals (Sweden)

    V. Angel

    2017-08-01

    Full Text Available In the face of changing economies and patterns of development, the definition of heritage is diversifying, and the role of inventories in local heritage planning is coming to the fore. The Durand neighbourhood is a layered and complex area located in inner-city Hamilton, Ontario, Canada, and the second subject area in a set of pilot inventory studies to develop a new city-wide inventory strategy for the City of Hamilton,. This paper presents an innovative digital workflow developed to undertake the Durand Built Heritage Inventory project. An online database was developed to be at the centre of all processes, including digital documentation, record management, analysis and variable outputs. Digital tools were employed for survey work in the field and analytical work in the office, resulting in a GIS-based dataset that can be integrated into Hamilton’s larger municipal planning system. Together with digital mapping and digitized historical resources, the Durand database has been leveraged to produce both digital and static outputs to shape recommendations for the protection of Hamilton’s heritage resources.

  6. Lax-Friedrichs sweeping scheme for static Hamilton-Jacobi equations

    International Nuclear Information System (INIS)

    Kao, C.Y.; Osher, Stanley; Qian Jianliang

    2004-01-01

    We propose a simple, fast sweeping method based on the Lax-Friedrichs monotone numerical Hamiltonian to approximate viscosity solutions of arbitrary static Hamilton-Jacobi equations in any number of spatial dimensions. By using the Lax-Friedrichs numerical Hamiltonian, we can easily obtain the solution at a specific grid point in terms of its neighbors, so that a Gauss-Seidel type nonlinear iterative method can be utilized. Furthermore, by incorporating a group-wise causality principle into the Gauss-Seidel iteration by following a finite group of characteristics, we have an easy-to-implement, sweeping-type, and fast convergent numerical method. However, unlike other methods based on the Godunov numerical Hamiltonian, some computational boundary conditions are needed in the implementation. We give a simple recipe which enforces a version of discrete min-max principle. Some convergence analysis is done for the one-dimensional eikonal equation. Extensive 2-D and 3-D numerical examples illustrate the efficiency and accuracy of the new approach. To our knowledge, this is the first fast numerical method based on discretizing the Hamilton-Jacobi equation directly without assuming convexity and/or homogeneity of the Hamiltonian

  7. Lax-Friedrichs sweeping scheme for static Hamilton-Jacobi equations

    Science.gov (United States)

    Kao, Chiu Yen; Osher, Stanley; Qian, Jianliang

    2004-05-01

    We propose a simple, fast sweeping method based on the Lax-Friedrichs monotone numerical Hamiltonian to approximate viscosity solutions of arbitrary static Hamilton-Jacobi equations in any number of spatial dimensions. By using the Lax-Friedrichs numerical Hamiltonian, we can easily obtain the solution at a specific grid point in terms of its neighbors, so that a Gauss-Seidel type nonlinear iterative method can be utilized. Furthermore, by incorporating a group-wise causality principle into the Gauss-Seidel iteration by following a finite group of characteristics, we have an easy-to-implement, sweeping-type, and fast convergent numerical method. However, unlike other methods based on the Godunov numerical Hamiltonian, some computational boundary conditions are needed in the implementation. We give a simple recipe which enforces a version of discrete min-max principle. Some convergence analysis is done for the one-dimensional eikonal equation. Extensive 2-D and 3-D numerical examples illustrate the efficiency and accuracy of the new approach. To our knowledge, this is the first fast numerical method based on discretizing the Hamilton-Jacobi equation directly without assuming convexity and/or homogeneity of the Hamiltonian.

  8. Source apportionment of PAH in Hamilton Harbour suspended sediments: comparison of two factor analysis methods.

    Science.gov (United States)

    Sofowote, Uwayemi M; McCarry, Brian E; Marvin, Christopher H

    2008-08-15

    A total of 26 suspended sediment samples collected over a 5-year period in Hamilton Harbour, Ontario, Canada and surrounding creeks were analyzed for a suite of polycyclic aromatic hydrocarbons and sulfur heterocycles. Hamilton Harbour sediments contain relatively high levels of polycyclic aromatic compounds and heavy metals due to emissions from industrial and mobile sources. Two receptor modeling methods using factor analyses were compared to determine the profiles and relative contributions of pollution sources to the harbor; these methods are principal component analyses (PCA) with multiple linear regression analysis (MLR) and positive matrix factorization (PMF). Both methods identified four factors and gave excellent correlation coefficients between predicted and measured levels of 25 aromatic compounds; both methods predicted similar contributions from coal tar/coal combustion sources to the harbor (19 and 26%, respectively). One PCA factor was identified as contributions from vehicular emissions (61%); PMF was able to differentiate vehicular emissions into two factors, one attributed to gasoline emissions sources (28%) and the other to diesel emissions sources (24%). Overall, PMF afforded better source identification than PCA with MLR. This work constitutes one of the few examples of the application of PMF to the source apportionment of sediments; the addition of sulfur heterocycles to the analyte list greatly aided in the source identification process.

  9. Ecological structuring of yeasts associated with trees around Hamilton, Ontario, Canada.

    Science.gov (United States)

    Maganti, Harinad; Bartfai, David; Xu, Jianping

    2012-02-01

    This study seeks to determine the distribution and diversity of yeasts in and around the Hamilton area in Canada. In light of the increasing number of fungal infections along with rising morbidity and mortality rates, especially among the immunocompromised, understanding the diversity and distribution of yeasts in natural environments close to human habitations has become an increasingly relevant topic. In this study, we analyzed 1110 samples obtained from the hollows of trees, shrubs and avian droppings at 8 geographical sites in and around Hamilton, Ontario, Canada. A total of 88 positive yeast strains were isolated and identified belonging to 20 yeast species. Despite the relative proximity of the sampling sites, our DNA fingerprinting results showed that the yeast populations were highly heterogenous. Among the 14 tree species sampled, cedar, cottonwood and basswood hollows had relatively high yeast colonization rates. Interestingly, Candida parapsilosis was isolated almost exclusively from Pine trees only. Our results are consistent with microgeographic and ecological differentiation of yeast species in and around an urban environment. © 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

  10. Expanded social fitness and Hamilton's rule for kin, kith, and kind.

    Science.gov (United States)

    Queller, David C

    2011-06-28

    Inclusive fitness theory has a combination of simplicity, generality, and accuracy that has made it an extremely successful way of thinking about and modeling effects on kin. However, there are types of social interactions that, although covered, are not illuminated. Here, I expand the inclusive fitness approach and the corresponding neighbor-modulated approach to specify two other kinds of social selection. Kind selection, which includes greenbeards and many nonadditive games, is where selection depends on an actor's trait having different effects on others depending on whether they share the trait. Kith selection includes social effects that do not require either kin or kind, such as mutualism and manipulation. It involves social effects of a trait that affect a partner, with feedback to the actor's fitness. I derive expanded versions of Hamilton's rule for kith and kind selection, generalizing Hamilton's insight that we can model social selection through a sum of fitness effects, each multiplied by an appropriate association coefficient. Kinship is, thus, only one of the important types of association, but all can be incorporated within an expanded inclusive fitness.

  11. On global solutions of the random Hamilton-Jacobi equations and the KPZ problem

    Science.gov (United States)

    Bakhtin, Yuri; Khanin, Konstantin

    2018-04-01

    In this paper, we discuss possible qualitative approaches to the problem of KPZ universality. Throughout the paper, our point of view is based on the geometrical and dynamical properties of minimisers and shocks forming interlacing tree-like structures. We believe that the KPZ universality can be explained in terms of statistics of these structures evolving in time. The paper is focussed on the setting of the random Hamilton-Jacobi equations. We formulate several conjectures concerning global solutions and discuss how their properties are connected to the KPZ scalings in dimension 1  +  1. In the case of general viscous Hamilton-Jacobi equations with non-quadratic Hamiltonians, we define generalised directed polymers. We expect that their behaviour is similar to the behaviour of classical directed polymers, and present arguments in favour of this conjecture. We also define a new renormalisation transformation defined in purely geometrical terms and discuss conjectural properties of the corresponding fixed points. Most of our conjectures are widely open, and supported by only partial rigorous results for particular models.

  12. Knowledge of General Nutrition, Soy Nutrition, and Consumption of Soy Products: Assessment of a Sample Adult Population in Montgomery County, Virginia

    OpenAIRE

    Johnson, Lida Catherine

    1999-01-01

    KNOWLEDGE OF GENERAL NUTRITION, SOY NUTRITION, AND CONSUMPTION OF SOY PRODUCTS: ASSESSMENT OF A SAMPLE ADULT POPULATION IN MONTGOMERY COUNTY, VIRGINIA Lida Catherine Johnson (ABSTRACT) Nutrition education programs in the prevention of chronic diseases has flourished over the last 15 years. Investigators continue to demonstrate that soy consumption plays a role in decreasing chronic diseases such as cardiovascular disease, cancer, osteoporosis and problems regarding menopause....

  13. The self-reported Montgomery-Åsberg depression rating scale is a useful evaluative tool in major depressive disorder

    Directory of Open Access Journals (Sweden)

    Fantino Bruno

    2009-05-01

    Full Text Available Abstract Background The use of Patient-reported Outcomes (PROs as secondary endpoints in the development of new antidepressants has grown in recent years. The objective of this study was to assess the psychometric properties of the 9-item, patient-administered version of the Montgomery-Åsberg Depression Rating Scale (MADRS-S. Methods Data from a multicentre, double-blind, 8-week, randomised controlled trial of 278 outpatients diagnosed with Major Depressive Disorder were used to evaluate the validity, reliability and sensitivity to change of the MADRS-S using psychometric methods. A Receiver Operating Characteristic (ROC curve was plotted to identify the most appropriate threshold to define perceived remission. Results No missing values were found at the item level, indicating good acceptability of the scale. The construct validity was satisfactory: all items contributed to a common underlying concept, as expected. The correlation between MADRS-S and physicians' MADRS was moderate (r = 0.54, p Conclusion Taking account of patient's perceptions of the severity of their own symptoms along with the psychometric properties of the MADRS-S enable its use for evaluative purposes in the development of new antidepressant drugs.

  14. Periodic solutions of the Hamilton-Jacobi equation by the shooting method: A technique for beam dynamics

    International Nuclear Information System (INIS)

    Gabella, W.E.; Ruth, R.D.; Warnock, R.L.

    1988-05-01

    Periodic solutions of the Hamilton-Jacobi equation determine invariant tori in phase space. The Fourier spectrum of a torus with respect to angular coordinates gives useful information about nonlinear resonances and their potential for causing instabilities. We describe a method to solve the Hamilton-Jacobi equation for an arbitrary accelerator lattice. The method works with Fourier modes of the generating functions, and imposes periodicity in the machine azimuth by a shooting method. We give examples leading to three-dimensional plots in a surface of section. It is expected that the technique will be useful in lattice optimization. 14 refs., 6 figs., 1 tab

  15. Hamilton-Jacobi formalism for inflation with non-minimal derivative coupling

    Energy Technology Data Exchange (ETDEWEB)

    Sheikhahmadi, Haidar [Institute for Advance Studies in Basic Sciences (IASBS) Gava Zang, Zanjan 45137-66731 (Iran, Islamic Republic of); Saridakis, Emmanuel N. [Instituto de Física, Pontificia Universidad de Católica de Valparaíso, Casilla 4950, Valparaíso (Chile); Aghamohammadi, Ali [Sanandaj Branch Islamic Azad University (Iran, Islamic Republic of); Saaidi, Khaled, E-mail: h.sh.ahmadi@gmail.com, E-mail: Emmanuel_Saridakis@baylor.edu, E-mail: a.aqamohamadi@iausdj.ac.ir, E-mail: ksaaidi@uok.ac.ir [Department of Physics, Faculty of Science, University of Kurdistan, Sanandaj (Iran, Islamic Republic of)

    2016-10-01

    In inflation with nonminimal derivative coupling there is not a conformal transformation to the Einstein frame where calculations are straightforward, and thus in order to extract inflationary observables one needs to perform a detailed and lengthy perturbation investigation. In this work we bypass this problem by performing a Hamilton-Jacobi analysis, namely rewriting the cosmological equations considering the scalar field to be the time variable. We apply the method to two specific models, namely the power-law and the exponential cases, and for each model we calculate various observables such as the tensor-to-scalar ratio, and the spectral index and its running. We compare them with 2013 and 2015 Planck data, and we show that they are in a very good agreement with observations.

  16. Hamilton-Jacobi approach for first order actions and theories with higher derivatives

    International Nuclear Information System (INIS)

    Bertin, M.C.; Pimentel, B.M.; Pompeia, P.J.

    2008-01-01

    In this work, we analyze systems described by Lagrangians with higher order derivatives in the context of the Hamilton-Jacobi formalism for first order actions. Two different approaches are studied here: the first one is analogous to the description of theories with higher derivatives in the hamiltonian formalism according to [D.M. Gitman, S.L. Lyakhovich, I.V. Tyutin, Soviet Phys. J. 26 (1983) 730; D.M. Gitman, I.V. Tyutin, Quantization of Fields with Constraints, Springer-Verlag, New York, Berlin, 1990] the second treats the case where degenerate coordinate are present, in an analogy to reference [D.M. Gitman, I.V. Tyutin, Nucl. Phys. B 630 (2002) 509]. Several examples are analyzed where a comparison between both approaches is made

  17. Hamilton-Jacobi formalism for inflation with non-minimal derivative coupling

    International Nuclear Information System (INIS)

    Sheikhahmadi, Haidar; Saridakis, Emmanuel N.; Aghamohammadi, Ali; Saaidi, Khaled

    2016-01-01

    In inflation with nonminimal derivative coupling there is not a conformal transformation to the Einstein frame where calculations are straightforward, and thus in order to extract inflationary observables one needs to perform a detailed and lengthy perturbation investigation. In this work we bypass this problem by performing a Hamilton-Jacobi analysis, namely rewriting the cosmological equations considering the scalar field to be the time variable. We apply the method to two specific models, namely the power-law and the exponential cases, and for each model we calculate various observables such as the tensor-to-scalar ratio, and the spectral index and its running. We compare them with 2013 and 2015 Planck data, and we show that they are in a very good agreement with observations.

  18. Filling the gaps in SCWR materials research: advanced nuclear corrosion research facilities in Hamilton

    International Nuclear Information System (INIS)

    Krausher, J.L.; Zheng, W.; Li, J.; Guzonas, D.; Botton, G.

    2011-01-01

    Research efforts on materials selection and development in support of the design of supercritical water-cooled reactors (SCWRs) have produced a considerable amount of data on corrosion, creep and other related properties. Summaries of the data on corrosion [1] and stress corrosion cracking [2] have recently been produced. As research on the SCWR advances, gaps and limitations in the published data are being identified. In terms of corrosion properties, these gaps can be seen in several areas, including: 1) the test environment, 2) the physical and chemical severity of the tests conducted as compared with likely reactor service/operating conditions, and 3) the test methods used. While some of these gaps can be filled readily using existing facilities, others require the availability of advanced test facilities for specific tests and assessments. In this paper, highlights of the new materials research facilities jointly established in Hamilton by CANMET Materials Technology Laboratory and McMaster University are presented. (author)

  19. Solutions to estimation problems for scalar hamilton-jacobi equations using linear programming

    KAUST Repository

    Claudel, Christian G.; Chamoin, Timothee; Bayen, Alexandre M.

    2014-01-01

    This brief presents new convex formulations for solving estimation problems in systems modeled by scalar Hamilton-Jacobi (HJ) equations. Using a semi-analytic formula, we show that the constraints resulting from a HJ equation are convex, and can be written as a set of linear inequalities. We use this fact to pose various (and seemingly unrelated) estimation problems related to traffic flow-engineering as a set of linear programs. In particular, we solve data assimilation and data reconciliation problems for estimating the state of a system when the model and measurement constraints are incompatible. We also solve traffic estimation problems, such as travel time estimation or density estimation. For all these problems, a numerical implementation is performed using experimental data from the Mobile Century experiment. In the context of reproducible research, the code and data used to compute the results presented in this brief have been posted online and are accessible to regenerate the results. © 2013 IEEE.

  20. Balance equations for a viscous fluid from a Hamilton type variational principle

    International Nuclear Information System (INIS)

    Fierros Palacios, A.

    1992-01-01

    The partial differential field equations for any viscous fluid are obtained from the Lagrangian formalism as in classical field theory. An action functional is introduced as a space-time integral over a region of three-dimensional Euclidean space, of a Lagrangian density function of certain field variables. A Hamilton type extremum action principle is postulated with adequate boundary conditions, and a set of differential field equations is derived. With an appropriate Lagrangian density of the T-V type, the equation of motion for any viscous fluid is reproduced. A theorem referring to the invariance of the action under time variations lead to the generalized energy balance equation for the viscous fluid and to the energy balance equation proper. The same theoretical approach can be used to solve the problem of potential flow. (Author)

  1. Field differential equations for a potential flow from a Hamilton type variational principle

    International Nuclear Information System (INIS)

    Fierros Palacios, A.

    1992-01-01

    The same theoretical frame that was used to solve the problem of the field equations for a viscous fluid is utilized in this work. The purpose is to obtain the differential field equations for a potential flow from the Lagrangian formalism as in classical field theory. An action functional is introduced as a space-time integral over a region of three-dimensional Euclidean space, of a Lagrangian density as a function of certain field variables. A Hamilton type extremum action principle is postulated with adequate boundary conditions, and a set of differential field equations is derived. A particular Lagrangian density of the T-V type leads to the wave equation for the velocity potential. (Author)

  2. Probabilistic formulation of estimation problems for a class of Hamilton-Jacobi equations

    KAUST Repository

    Hofleitner, Aude; Claudel, Christian G.; Bayen, Alexandre M.

    2012-01-01

    This article presents a method for deriving the probability distribution of the solution to a Hamilton-Jacobi partial differential equation for which the value conditions are random. The derivations lead to analytical or semi-analytical expressions of the probability distribution function at any point in the domain in which the solution is defined. The characterization of the distribution of the solution at any point is a first step towards the estimation of the parameters defining the random value conditions. This work has important applications for estimation in flow networks in which value conditions are noisy. In particular, we illustrate our derivations on a road segment with random capacity reductions. © 2012 IEEE.

  3. Superintegrability on curved spaces, orbits and momentum hodographs: revisiting a classical result by Hamilton

    International Nuclear Information System (INIS)

    Carinena, Jose F; Ranada, Manuel F; Santander, Mariano

    2007-01-01

    The equation of the orbits (in the configuration space) and of the hodographs (in the 'momentum' plane) for the 'curved' Kepler and harmonic oscillator systems, living in a configuration space of any constant curvature and either signature type, are derived by purely algebraic means. This result extends to the 'curved' Kepler or harmonic oscillator for the classical Hamilton derivation of the orbits of the Euclidean Kepler problem through its hodographs. In both cases, the fundamental property allowing these derivations to work is the superintegrability of the 'curved' Kepler and harmonic oscillator, no matter whether the constant curvature of the configuration space is zero or not, or whether the configuration space metric is Riemannian or Lorentzian. In the 'curved' case the basic result does not refer to the 'velocity hodograph' but to the 'momentum hodograph'; both coincide in a Euclidean configuration space, but only the latter is unambiguously defined in all curved spaces

  4. [«I stole with my eyes»: Hamilton Naki, a pioneer in heart transplantation].

    Science.gov (United States)

    López-Valdés, Julio César

    On December 2, 1967, when Denise Darvall was hit by a car, a surgery that made medical history was unfold: Hamilton Naki, a black man, expertly removed her heart and gave it to Christian Barnard, who was preparing the receptor, Louis Washkansky, in an adjacent operating room. Naki's contribution was an outlaw act, a criminal offense under the laws of apartheid due to the difference of races; the law forbade him to cut white meat or touch white blood. Naki was perhaps the second most important man in the team that day. There were few photographs where he and Barnard appeared together, but because of the nature of society was Barnard who won the world's attention.

  5. Probabilistic formulation of estimation problems for a class of Hamilton-Jacobi equations

    KAUST Repository

    Hofleitner, Aude

    2012-12-01

    This article presents a method for deriving the probability distribution of the solution to a Hamilton-Jacobi partial differential equation for which the value conditions are random. The derivations lead to analytical or semi-analytical expressions of the probability distribution function at any point in the domain in which the solution is defined. The characterization of the distribution of the solution at any point is a first step towards the estimation of the parameters defining the random value conditions. This work has important applications for estimation in flow networks in which value conditions are noisy. In particular, we illustrate our derivations on a road segment with random capacity reductions. © 2012 IEEE.

  6. Direct oral anticoagulants for treatment of HIT: update of Hamilton experience and literature review.

    Science.gov (United States)

    Warkentin, Theodore E; Pai, Menaka; Linkins, Lori-Ann

    2017-08-31

    Direct oral anticoagulants (DOACs) are attractive options for treatment of heparin-induced thrombocytopenia (HIT). We report our continuing experience in Hamilton, ON, Canada, since January 1, 2015 (when we completed our prospective study of rivaroxaban for HIT), using rivaroxaban for serologically confirmed HIT (4Ts score ≥4 points; positive platelet factor 4 [PF4]/heparin immunoassay, positive serotonin-release assay). We also performed a literature review of HIT treatment using DOACs (rivaroxaban, apixaban, dabigatran, edoxaban). We focused on patients who received DOAC therapy for acute HIT as either primary therapy (group A) or secondary therapy (group B; initial treatment using a non-DOAC/non-heparin anticoagulant with transition to a DOAC during HIT-associated thrombocytopenia). Our primary end point was occurrence of objectively documented thrombosis during DOAC therapy for acute HIT. We found that recovery without new, progressive, or recurrent thrombosis occurred in all 10 Hamilton patients with acute HIT treated with rivaroxaban. Data from the literature review plus these new data identified a thrombosis rate of 1 of 46 patients (2.2%; 95% CI, 0.4%-11.3%) in patients treated with rivaroxaban during acute HIT (group A, n = 25; group B, n = 21); major hemorrhage was seen in 0 of 46 patients. Similar outcomes in smaller numbers of patients were observed with apixaban (n = 12) and dabigatran (n = 11). DOACs offer simplified management of selected patients, as illustrated by a case of persisting (autoimmune) HIT (>2-month platelet recovery with inversely parallel waning of serum-induced heparin-independent serotonin release) with successful outpatient rivaroxaban management of HIT-associated thrombosis. Evidence supporting efficacy and safety of DOACs for acute HIT is increasing, with the most experience reported for rivaroxaban. © 2017 by The American Society of Hematology.

  7. On the Geometry of the Hamilton-Jacobi Equation and Generating Functions

    Science.gov (United States)

    Ferraro, Sebastián; de León, Manuel; Marrero, Juan Carlos; Martín de Diego, David; Vaquero, Miguel

    2017-10-01

    In this paper we develop a geometric version of the Hamilton-Jacobi equation in the Poisson setting. Specifically, we "geometrize" what is usually called a complete solution of the Hamilton-Jacobi equation. We use some well-known results about symplectic groupoids, in particular cotangent groupoids, as a keystone for the construction of our framework. Our methodology follows the ambitious program proposed by Weinstein (In Mechanics day (Waterloo, ON, 1992), volume 7 of fields institute communications, American Mathematical Society, Providence, 1996) in order to develop geometric formulations of the dynamical behavior of Lagrangian and Hamiltonian systems on Lie algebroids and Lie groupoids. This procedure allows us to take symmetries into account, and, as a by-product, we recover results from Channell and Scovel (Phys D 50(1):80-88, 1991), Ge (Indiana Univ. Math. J. 39(3):859-876, 1990), Ge and Marsden (Phys Lett A 133(3):134-139, 1988), but even in these situations our approach is new. A theory of generating functions for the Poisson structures considered here is also developed following the same pattern, solving a longstanding problem of the area: how to obtain a generating function for the identity transformation and the nearby Poisson automorphisms of Poisson manifolds. A direct application of our results gives the construction of a family of Poisson integrators, that is, integrators that conserve the underlying Poisson geometry. These integrators are implemented in the paper in benchmark problems. Some conclusions, current and future directions of research are shown at the end of the paper.

  8. Validation of Montgomery-Åsberg Rating Scale and Cornell Scale for Depression in Dementia in Brazilian elderly patients.

    Science.gov (United States)

    Portugal, Maria da Glória; Coutinho, Evandro Silva Freire; Almeida, Cloyra; Barca, Maria Lage; Knapskog, Anne-Brita; Engedal, Knut; Laks, Jerson

    2012-08-01

    There are few studies on validation of depression scales in the elderly in Latin America. This study aimed to assess the validity of Montgomery-Åsberg. Depression Rating Scale (MADRS) and Cornell Scale for Depression in Dementia (CSDD) in Brazilian elderly outpatients. A convenience sample of 95 outpatients was diagnosed for dementia and depression according to DSM-IV-TR, ICD-10, and PDC-dAD criteria. Receiver Operating Curves (ROC) were used to calculate the area under the curve (AUC) and to assess MADRS and CSDD cut-offs for each diagnostic criterion. Dementia was diagnosed in 71 of 95 patients. Depression was diagnosed in 35, 30, and 51 patients by ICD-10, DSM-IV, and PDC-dAD, respectively. MADRS cut-off score of 10 correctly diagnosed 67.4% and 66.3% patients as depressed according to DSM-IV and ICD-10. A cut-off of 9 correctly identified 74.7% by PDC-dAD criteria; a CSDD cut-off score of 13 best recognized depression according to DSM-IV and ICD-10. A score of 11 diagnosed depression according to PDC-dAD, while MADRS = 9 recognized depression in dementia. CSDD was more efficient in showing depression in mild than in moderate/severe dementia according to DSM-IV/ICD-10. PDC-dAD behaved nicely for any severity stage. MADRS and CSDD cut-offs of 10 and 13 were the optimal ones to diagnose depression in elderly, respectively. CSDD cut-offs are higher than those found in other countries. Other Latin American studies are needed to compare results with our study.

  9. Chaos M-ary modulation and demodulation method based on Hamilton oscillator and its application in communication.

    Science.gov (United States)

    Fu, Yongqing; Li, Xingyuan; Li, Yanan; Yang, Wei; Song, Hailiang

    2013-03-01

    Chaotic communication has aroused general interests in recent years, but its communication effect is not ideal with the restriction of chaos synchronization. In this paper a new chaos M-ary digital modulation and demodulation method is proposed. By using region controllable characteristics of spatiotemporal chaos Hamilton map in phase plane and chaos unique characteristic, which is sensitive to initial value, zone mapping method is proposed. It establishes the map relationship between M-ary digital information and the region of Hamilton map phase plane, thus the M-ary information chaos modulation is realized. In addition, zone partition demodulation method is proposed based on the structure characteristic of Hamilton modulated information, which separates M-ary information from phase trajectory of chaotic Hamilton map, and the theory analysis of zone partition demodulator's boundary range is given. Finally, the communication system based on the two methods is constructed on the personal computer. The simulation shows that in high speed transmission communications and with no chaos synchronization circumstance, the proposed chaotic M-ary modulation and demodulation method has outperformed some conventional M-ary modulation methods, such as quadrature phase shift keying and M-ary pulse amplitude modulation in bit error rate. Besides, it has performance improvement in bandwidth efficiency, transmission efficiency and anti-noise performance, and the system complexity is low and chaos signal is easy to generate.

  10. Welcome to My House: African American and European American Students' Responses to Virginia Hamilton's "House of Dies Drear."

    Science.gov (United States)

    Spears-Bunton, Linda A.

    1990-01-01

    Addresses the relationship between reader response and culture. Presents portraits of a teacher and her Black students and White students as they studied a series of African American literary texts, including Virginia Hamilton's "House of Dies Drear" (1968). The reading of this text marked a turning point for the teacher and students.…

  11. HYDROLOGY, MONTGOMERY COUNTY, MISSISSIPPI

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydrology data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a flood insurance...

  12. Quantized Hamilton dynamics describes quantum discrete breathers in a simple way

    International Nuclear Information System (INIS)

    Igumenshchev, Kirill; Prezhdo, Oleg

    2011-01-01

    We study the localization of energy in a nonlinear coupled system, exhibiting so-called breather modes, using quantized Hamilton dynamics (QHD). Already at the lowest order, which is only twice as complex as classical mechanics, this simple semiclassical method incorporates quantum-mechanical effects. The transition between the localized and delocalized regimes is instantaneous in classical mechanics, while it is gradual due to tunneling in both quantum mechanics and QHD. In contrast to classical mechanics, which predicts an abrupt appearance of breathers, quantum mechanics and QHD show an alternation of localized and delocalized behavior in the transient region. QHD includes zero-point energy that is reflected in a shifted energy asymptote for the localized states, providing another improvement on the classical perspective. By detailed analysis of the distribution and transfer of energy within classical mechanics, QHD, and quantum dynamics, we conclude that QHD is an efficient approach that accounts for moderate quantum effects and can be used to identify quantum breathers in large nonlinear systems.

  13. Hamilton-Jacobi approach for quasi-exponential inflation: predictions and constraints after Planck 2015 results

    Energy Technology Data Exchange (ETDEWEB)

    Videla, Nelson [FCFM, Universidad de Chile, Departamento de Fisica, Santiago (Chile)

    2017-03-15

    In the present work we study the consequences of considering an inflationary universe model in which the Hubble rate has a quasi-exponential dependence in the inflaton field, given by H(φ) = H{sub inf} exp[((φ)/(m{sub p}))/(p(1+(φ)/(m{sub p})))]. We analyze the inflation dynamics under the Hamilton-Jacobi approach, which allows us to consider H(φ), rather than V(φ), as the fundamental quantity to be specified. By comparing the theoretical predictions of the model together with the allowed contour plots in the n{sub s} - r plane and the amplitude of primordial scalar perturbations from the latest Planck data, the parameters charactering this model are constrained. The model predicts values for the tensor-to-scalar ratio r and for the running of the scalar spectral index dn{sub s}/d ln k consistent with the current bounds imposed by Planck, and we conclude that the model is viable. (orig.)

  14. Potential demand for household alternative fuelled vehicles in Hamilton, Canada : a stated choices experiment and survey

    Energy Technology Data Exchange (ETDEWEB)

    Potoglou, D.; Kanaroglou, P.S. [McMaster Univ., Hamilton, ON (Canada). Centre for Spatial Analysis]|[McMaster Univ., Hamilton, ON (Canada). School of Geography and Earth Science

    2005-07-01

    Alternative fuelled vehicle (AFV) technologies are a key strategy towards improved air quality and sustainable development. These fuel-efficient, low- or zero-emission vehicles have the potential to reduce greenhouse gas emissions and other negative externalities linked with the transportation sector. They include battery electric vehicles, fuel cell vehicles, and hybrid electric vehicles with internal combustion engines. This paper discussed AFVs development trends and modelling the demand for AFVs. It was noted that before creating policy measures that promote new vehicle technologies, one should first evaluate the demand for AFVs and the effectiveness of incentives and marketing promotions. This paper discussed the design and application of a stated choices experiment in which urban level surveys were conducted on the Internet to obtain data and public opinion on the demand for AFVs. A Choice Internet Based Experiment for Research on Cars (CIBER-CARS) was designed. This self-administered online questionnaire was used in Hamilton, Ontario. The survey design was described in detail and its implementation and data collection procedures were reviewed. Measures for evaluating the efficiency of the Internet survey were also highlighted and the characteristics of the collected information were summarized with emphasis on the profiles of respondents and households. The purpose was to determine the impact of vehicle attributes and household characteristics to the actual choice of certain vehicles. 28 refs., 2 tabs., 4 figs.

  15. DDT poisoning of big brown bats, Eptesicus fuscus, in Hamilton, Montana.

    Science.gov (United States)

    Buchweitz, John P; Carson, Keri; Rebolloso, Sarah; Lehner, Andreas

    2018-06-01

    Dichlorodiphenyltrichloroethane (DDT) is an insecticidal organochlorine pesticide with; known potential for neurotoxic effects in wildlife. The United States Environmental Protection Agency (US EPA) registration for this pesticide has been cancelled and there are currently no federally active products that contain this ingredient in the U.S. We present a case of a colony of big brown bats (E. Fuscus) found dead in the attic roost of an administrative building; in the city of Hamilton, Montana from unknown cause. DDT and its metabolites; dichlorodiphenyldichloroethylene (DDE) and dichlorodiphenyldichloroethane (DDD) were detected in bat tissues by gas chromatography/mass spectrometry (GC-MS) and quantified by gas chromatography tandem quadrupole mass spectrometry (GC-MS/MS). Concentrations of 4081 ppm DDT and 890 ppm DDE wet weight were found in the brain of one bat and are the highest reported concentrations in such a mortality event to date. This case emphasizes the importance of testing wildlife mortalities against a comprehensive panel of toxicologic agents including persistent organic pollutants in the absence of other more common disease threats. Copyright © 2018 Elsevier Ltd. All rights reserved.

  16. Histomorphological and microanatomical characteristics of the olfactory organ of freshwater carp, Cirrhinus reba (Hamilton

    Directory of Open Access Journals (Sweden)

    Ghosh Saroj Kumar

    2016-12-01

    Full Text Available The morphoanatomy, cellular organization, and surface architecture of the olfactory apparatus in Cirrhinus reba (Hamilton is described using light and scanning electron microscopy. The oval shaped olfactory rosette contained 32 ± 2 primary lamellae on each side of the median raphe, and was lodged on the floor of the olfactory chamber. The olfactory lamellae were basically flat and compactly arranged in the rosette. The olfactory chamber communicated to the outside aquatic environment through inlet and outlet apertures with a conspicuous nasal flap in between. The mid dorsal portion of the olfactory lamellae was characterized by a linguiform process. Sensory and non-sensory regions were distributed separately on each lamella. The sensory epithelium occupied the apical part including the linguiform process, whereas the resting part of the lamella was covered with non-sensory epithelium. The sensory epithelium comprised both ciliated and microvillous receptor cells distinguished by the architecture on their apical part. The non-sensory epithelium possessed mucous cells, labyrinth cells, and stratified epithelial cells with distinctive microridges. The functional importance of the different cells lining the olfactory mucosa was correlated with the ecological habits of the fish examined.

  17. Lie-admissible structure of Hamilton's original equations with external terms

    International Nuclear Information System (INIS)

    Santilli, R.M.

    1991-09-01

    As a necessary additional step in preparation of our operator studies of closed nonhamiltonian systems, in this note we consider the algebraic structure of the original equations proposed by Lagrange and Hamilton, those with external terms representing precisely the contact nonpotential forces of the interior dynamical problem. We show that the brackets of the theory violate the conditions to characterize any algebra. Nevertheless, when properly written, they characterize a covering of the Lie-isotopic algebras called Lie-admissible algebras. It is indicated that a similar occurrence exists for conventional operator treatments, e.g. for nonconservative nuclear cases characterized by nonhermitean Hamiltonians. This occurrence then prevents a rigorous treatment of basic notions, such as that of angular momentum and spin spin, which are centrally dependent on the existence of a consistent algebraic structure. The emergence of the Lie-admissible algebras is therefore expected to be unavoidable for any rigorous operator treatment of open systems with nonlinear, nonlocal and nonhamiltonian external forces. (author). 14 refs, 1 fig

  18. Hamilton-Ostrogradsky principle in the theory of nonlinear elasticity with the combined approach

    International Nuclear Information System (INIS)

    Sporykhin, A.N.

    1995-01-01

    The assignment of a portion of the edge conditions in the deformed state and a portion of them in the initial state so that the initial and deformed states of the body are unknowns is a characteristic feature of the statement of a number of technological problems. Haber and Haber and Abel have performed studies in this direction, where constitutive relationships have been constructed within the framework of a linearly elastic material. Use of the displacements of individual particles as variable parameters in these relationships has required additional conditions that do not follow from the formulated problem. Use of familiar variational principles described in Euler coordinates is rendered difficult by the complexity of edge-condition formulation in the special case when the initial state is unknown. The latter is governed by the fact that variational principles are derived from the initial formulations open-quotes in Lagrangian coordinates,close quotes by recalculating the operation functional. Using Lagrange's principle, Novikov and Sporykhin constructed constitutive equations in the general case of a nonlinearly elastic body with edge conditions assigned in different configurations. An analogous problem is solved in this paper using the Hamilton-Ostrogradsky principle

  19. Susceptibility and pathological consequences of catla, Catla catla (Hamilton experimentally infected with Edwardsiella tarda

    Directory of Open Access Journals (Sweden)

    Devi Thongam Bidya

    2016-12-01

    Full Text Available The present study tested the susceptibility and pathological changes of catla, Catla catla (Hamilton infected with Edwardsiella tarda (ET-PG-29. The bacterium was isolated from the kidney of a diseased pangas catfish. To determine the median lethal dose (LD50, C. catla were challenged with this bacterium (108-103 CFU ml-1, and the LD50 was calculated as 105.5 CFU ml-1. Another set of healthy C. catla were injected intraperitoneally with the LD50 dose to induce edwardsiellosis. The clinical signs of the infected C. catla were observed and recorded. Tissues such as kidney, liver, intestine, heart, and gill from the infected fish with clinical signs of edwardsiellosis were used for histopathology. The clinical and gross signs were first visible at 1 d post-injection, and the infected fish showed typical signs of hemorrhagic septicemia. The most striking histopathological features were found in the kidney which showed multi-focal necrosis with the formation of granuloma indicating an inflammatory response against the pathogen. The intestine displayed goblet cell hyperplasia, the liver showed hydropic degeneration with hyperemic central veins, and there was inflammation of gill lamellae and cardiac myositis associated with leucocyte infiltration. Collectively, the results confirmed the susceptibility of C. catla to E. tarda infection and that this bacterium is a threat to C. catla in aquaculture practices.

  20. Well-spread sequences and edge-labellings with constant Hamilton-weight

    Directory of Open Access Journals (Sweden)

    P. Mark Kayll

    2004-12-01

    Full Text Available A sequence (a i of integers is well-spread if the sums a i +a j, for iHamilton cycle has the same length; we prove that 2n 2-O(n 3/2<Λ(n<2n 2 +O(n 61/40.

  1. Factor analysis of the Hamilton Depression Rating Scale in Parkinson's disease.

    Science.gov (United States)

    Broen, M P G; Moonen, A J H; Kuijf, M L; Dujardin, K; Marsh, L; Richard, I H; Starkstein, S E; Martinez-Martin, P; Leentjens, A F G

    2015-02-01

    Several studies have validated the Hamilton Depression Rating Scale (HAMD) in patients with Parkinson's disease (PD), and reported adequate reliability and construct validity. However, the factorial validity of the HAMD has not yet been investigated. The aim of our analysis was to explore the factor structure of the HAMD in a large sample of PD patients. A principal component analysis of the 17-item HAMD was performed on data of 341 PD patients, available from a previous cross sectional study on anxiety. An eigenvalue ≥1 was used to determine the number of factors. Factor loadings ≥0.4 in combination with oblique rotations were used to identify which variables made up the factors. Kaiser-Meyer-Olkin measure (KMO), Cronbach's alpha, Bartlett's test, communality, percentage of non-redundant residuals and the component correlation matrix were computed to assess factor validity. KMO verified the sample's adequacy for factor analysis and Cronbach's alpha indicated a good internal consistency of the total scale. Six factors had eigenvalues ≥1 and together explained 59.19% of the variance. The number of items per factor varied from 1 to 6. Inter-item correlations within each component were low. There was a high percentage of non-redundant residuals and low communality. This analysis demonstrates that the factorial validity of the HAMD in PD is unsatisfactory. This implies that the scale is not appropriate for studying specific symptom domains of depression based on factorial structure in a PD population. Copyright © 2014 Elsevier Ltd. All rights reserved.

  2. Husbandry stress exacerbates mycobacterial infections in adult zebrafish, Danio rerio (Hamilton)

    Science.gov (United States)

    Ramsay, J.M.; Watral, Virginia G.; Schreck, C.B.; Kent, M.L.

    2009-01-01

    Mycobacteria are significant pathogens of laboratory zebrafish, Danio rerio (Hamilton). Stress is often implicated in clinical disease and morbidity associated with mycobacterial infections but has yet to be examined with zebrafish. The aim of this study was to examine the effects of husbandry stressors on zebrafish infected with mycobacteria. Adult zebrafish were exposed to Mycobacterium marinum or Mycobacterium chelonae, two species that have been associated with disease in zebrafish. Infected fish and controls were then subjected to chronic crowding and handling stressors and examined over an 8-week period. Whole-body cortisol was significantly elevated in stressed fish compared to non-stressed fish. Fish infected with M. marinum ATCC 927 and subjected to husbandry stressors had 14% cumulative mortality while no mortality occurred among infected fish not subjected to husbandry stressors. Stressed fish, infected with M. chelonae H1E2 from zebrafish, were 15-fold more likely to be infected than non-stressed fish at week 8 post-injection. Sub-acute, diffuse infections were more common among stressed fish infected with M. marinum or M. chelonae than non-stressed fish. This is the first study to demonstrate an effect of stress and elevated cortisol on the morbidity, prevalence, clinical disease and histological presentation associated with mycobacterial infections in zebrafish. Minimizing husbandry stress may be effective at reducing the severity of outbreaks of clinical mycobacteriosis in zebrafish facilities. ?? 2009 Blackwell Publishing Ltd.

  3. Communication and relationship skills for rapid response teams at hamilton health sciences.

    Science.gov (United States)

    Cziraki, Karen; Lucas, Janie; Rogers, Toni; Page, Laura; Zimmerman, Rosanne; Hauer, Lois Ann; Daniels, Charlotte; Gregoroff, Susan

    2008-01-01

    Rapid response teams (RRT) are an important safety strategy in the prevention of deaths in patients who are progressively failing outside of the intensive care unit. The goal is to intervene before a critical event occurs. Effective teamwork and communication skills are frequently cited as critical success factors in the implementation of these teams. However, there is very little literature that clearly provides an education strategy for the development of these skills. Training in simulation labs offers an opportunity to assess and build on current team skills; however, this approach does not address how to meet the gaps in team communication and relationship skill management. At Hamilton Health Sciences (HHS) a two-day program was developed in collaboration with the RRT Team Leads, Organizational Effectiveness and Patient Safety Leaders. Participants reflected on their conflict management styles and considered how their personality traits may contribute to team function. Communication and relationship theories were reviewed and applied in simulated sessions in the relative safety of off-site team sessions. The overwhelming positive response to this training has been demonstrated in the incredible success of these teams from the perspective of the satisfaction surveys of the care units that call the team, and in the multi-phased team evaluation of their application to practice. These sessions offer a useful approach to the development of the soft skills required for successful RRT implementation.

  4. Excellent reliability of the Hamilton Depression Rating Scale (HDRS-21) in Indonesia after training.

    Science.gov (United States)

    Istriana, Erita; Kurnia, Ade; Weijers, Annelies; Hidayat, Teddy; Pinxten, Lucas; de Jong, Cor; Schellekens, Arnt

    2013-09-01

    The Hamilton Depression Rating Scale (HDRS) is the most widely used depression rating scale worldwide. Reliability of HDRS has been reported mainly from Western countries. The current study tested the reliability of HDRS ratings among psychiatric residents in Indonesia, before and after HDRS training. The hypotheses were that: (i) prior to the training reliability of HDRS ratings is poor; and (ii) HDRS training can improve reliability of HDRS ratings to excellent levels. Furthermore, we explored cultural validity at item level. Videotaped HDRS interviews were rated by 30 psychiatric residents before and after 1 day of HDRS training. Based on a gold standard rating, percentage correct ratings and deviation from the standard were calculated. Correct ratings increased from 83% to 99% at item level and from 70% to 100% for the total rating. The average deviation from the gold standard rating improved from 0.07 to 0.02 at item level and from 2.97 to 0.46 for the total rating. HDRS assessment by psychiatric trainees in Indonesia without prior training is unreliable. A short, evidence-based HDRS training improves reliability to near perfect levels. The outlined training program could serve as a template for HDRS trainings. HDRS items that may be less valid for assessment of depression severity in Indonesia are discussed. Copyright © 2013 Wiley Publishing Asia Pty Ltd.

  5. Characterization of phenolics by LC-UV/vis, LC-MS/MS and sugars by GC in Melicoccus bijugatus Jacq. 'Montgomery' fruits.

    Science.gov (United States)

    Bystrom, Laura M; Lewis, Betty A; Brown, Dan L; Rodriguez, Eloy; Obendorf, Ralph L

    2008-12-15

    Fruits of the native South American tree Melicoccus bijugatus Jacq. (Sapindaceae) are consumed for both dietary and medicinal purposes, but limited information is available about the phytochemistry and health value of M. bijugatus fruits. Fruit tissues of the Florida Montgomery cultivar were assessed for sugars, using gas chromatography, and for total phenolics, using UV spectroscopy. Reverse phase high performance liquid chromatography (HPLC) fingerprints of crude methanolic pulp, embryo and seed coat extracts were obtained at 280 nm. Phenolics were characterised by both HPLC UV/vis analysis and HPLC electrospray ionization tandem mass spectrometry. Major sugars detected in the pulp and embryo extracts were sucrose, followed by glucose and fructose. The glucose:fructose ratio was 1:1 in the pulp and 0.1:1 in the embryo. Total phenolic concentrations of the fruit tissues were in the order: seed coat > embryo > pulp. Phenolic acids were identified mostly in pulp tissues. Phenolic acids, flavonoids, procyanidins and catechins were identified in embryo tissues, and higher molecular weight procyanidins were identified in seed coat tissues. This study provides new information about the phytochemistry and the potential health value of the Montgomery cultivar M. bijugatus fruit tissues.

  6. Final work plan : phase I investigation of potential contamination at the former CCC/USDA grain storage facility in Montgomery City, Missouri.

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, L. M.; Environmental Science Division

    2010-08-16

    From September 1949 until September 1966, the Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA) leased property at the southeastern end of Montgomery City, Missouri, for the operation of a grain storage facility. During this time, commercial grain fumigants containing carbon tetrachloride were commonly used by the CCC/USDA and the private grain storage industry to preserve grain in their facilities. In January 2000, carbon tetrachloride was detected in a soil sample (220 {micro}g/kg) and two soil gas samples (58 {micro}g/m{sup 3} and 550 {micro}g/m{sup 3}) collected at the former CCC/USDA facility, as a result of a pre-CERCLIS site screening investigation (SSI) performed by TN & Associates, Inc., on behalf of the U.S. Environmental Protection Agency (EPA), Region VII (MoDNR 2001). In June 2001, the Missouri Department of Natural Resources (MoDNR) conducted further sampling of the soils and groundwater at the former CCC/USDA facility as part of a preliminary assessment/site inspection (PA/SI). The MoDNR confirmed the presence of carbon tetrachloride (at a maximum identified concentration of 2,810 {micro}g/kg) and chloroform (maximum 82 {micro}g/kg) in the soils and also detected carbon tetrachloride and chloroform (42.2 {micro}g/L and 58.4 {micro}g/L, respectively) in a groundwater sample collected at the former facility (MoDNR 2001). The carbon tetrachloride levels identified in the soils and groundwater are above the default target level (DTL) values established by the MoDNR for this contaminant in soils of all types (79.6 {micro}g/kg) and in groundwater (5.0 {micro}g/L), as outlined in Missouri Risk-Based Corrective Action (MRBCA): Departmental Technical Guidance (MoDNR 2006a). The corresponding MRBCA DTL values for chloroform are 76.6 {micro}g/kg in soils of all types and 80 {micro}g/L in groundwater. Because the observed contamination at Montgomery City might be linked to the past use of carbon tetrachloride-based fumigants at its

  7. The role of interfacial layers in the enhanced thermal conductivity of nanofluids: A renovated Hamilton-Crosser model

    International Nuclear Information System (INIS)

    Yu, W; Choi, S.U.S.

    2004-01-01

    We previously developed a renovated Maxwell model for the effective thermal conductivity of nanofluids and determined that the solid/liquid interfacial layers play an important role in the enhanced thermal conductivity of nanofluids. However, this renovated Maxwell model is limited to suspensions with spherical particles. Here, we extend the Hamilton--Crosser model for suspensions of nonspherical particles to include the effect of a solid/liquid interface. The solid/liquid interface is described as a confocal ellipsoid with a solid particle. The new model for the three-phase suspensions is mathematically expressed in terms of the equivalent thermal conductivity and equivalent volume fraction of anisotropic complex ellipsoids, as well as an empirical shape factor. With a generalized empirical shape factor, the renovated Hamilton--Crosser model correctly predicts the magnitude of the thermal conductivity of nanotube-in-oil nanofluids. At present, this new model is not able to predict the nonlinear behavior of the nanofluid thermal conductivity

  8. Integrating factors and conservation theorems for Hamilton's canonical equations of motion of variable mass nonholonomic nonconservative dynamical systems

    Institute of Scientific and Technical Information of China (English)

    李仁杰; 乔永芬; 刘洋

    2002-01-01

    We present a general approach to the construction of conservation laws for variable mass nonholonomic noncon-servative systems. First, we give the definition of integrating factors, and we study in detail the necessary conditionsfor the existence of the conserved quantities. Then, we establish the conservation theorem and its inverse theorem forHamilton's canonical equations of motion of variable mass nonholonomic nonconservative dynamical systems. Finally,we give an example to illustrate the application of the results.

  9. Traditional Korean islanders encounters with the British navy in the 1880s: The Port Hamilton Affair of 1885–1887

    Directory of Open Access Journals (Sweden)

    Stephen A. Royle

    2016-06-01

    Full Text Available This article deals with the encounters between a traditional Korean rural and island population and western military forces when the British navy occupied Geomundo, an archipelago known to them as Port Hamilton, for 22 months between 1885 and 1887. The paper first outlines the sometimes painful process of East Asian countries being opened up to trade and outside influences in the 19th century, a process sometimes urged upon them by naval weapons in this era of gunboat diplomacy. This provides the setting for the Port Hamilton Affair itself when in preparation for possible war with Russia, a British naval squadron steamed into Port Hamilton and took it without reference to the local people or their national government. After brief reference to the political consequences of this action, the focus is then on what the records from the occupation and earlier investigations by the British, who had long coveted the islands’ strategic harbour, reveal about the life of the islanders. The article considers both their traditional life, from a time rather before western travel accounts were written about the Korean mainland, and how the islanders fared under the British.

  10. Disaggregate demand for conventional and alternative fuelled vehicles in the Census Metropolitan Area of Hamilton, Canada

    Science.gov (United States)

    Potoglou, Dimitrios

    The focus of this thesis is twofold. First, it offers insight on how households' car-ownership behaviour is affected by urban form and availability of local-transit at the place of residence, after controlling for socio-economic and demographic characteristics. Second, it addresses the importance of vehicle attributes, household and individual characteristics as well as economic incentives and urban form to potential demand for alternative fuelled vehicles. Data for the empirical analyses of the aforementioned research activities were obtained through an innovative Internet survey, which is also documented in this thesis, conducted in the Census Metropolitan Area of Hamilton. The survey included a retrospective questionnaire of households' number and type of vehicles and a stated choices experiment for assessing the potential demand for alternative fuelled vehicles. Established approaches and emerging trends in automobile demand modelling identified early on in this thesis suggest a disaggregate approach and specifically, the estimation of discrete choice models both for explaining car ownership and vehicle-type choice behaviour. It is shown that mixed and diverse land uses as well as short distances between home and work are likely to decrease the probability of households to own a large number of cars. Regarding the demand for alternative fuelled vehicles, while vehicle attributes are particularly important, incentives such as free parking and access to high occupancy vehicle lanes will not influence the choice of hybrids or alternative fuelled vehicles. An improved understating of households' behaviour regarding the number of cars as well as the factors and trade-offs for choosing cleaner vehicles can be used to inform policy designed to reduce car ownership levels and encourage adoption of cleaner vehicle technologies in urban areas. Finally, the Internet survey sets the ground for further research on implementation and evaluation of this data collection method.

  11. Biometrics of the rare fish Rhinomugil corsula (Hamilton, 1822 (Mugiliformes: Mugilidae in the Ganges, Northwestern Bangladesh

    Directory of Open Access Journals (Sweden)

    Md. Yeamin Hossain

    2013-11-01

    Full Text Available Objective: To investigate biometrics of the Rhinomugil corsula (Hamilton, 1822 (R. corsula, including length-weight relationships (LWRs, condition factors (Allometric, KA; Fulton’s, KF; Relative, KR; Relative weight, WR, and sex ratio and length-frequency distributions in the Ganges (Padma River, Northwestern Bangladesh. Methods: Monthly sampling was conducted using traditional fishing gears during June to August 2012. Total length was measured to the nearest 0.01 cm using digital slide calipers, and total body weight was measured using an electronic balance with 0.01 g accuracy. The LWR was calculated using the expression: W= a×Lb , where the W is the body weight , L is the total length , a and b are the parameters of the regression. Results: A total of 350 specimens ranging from 8.59-15.71 cm in total length and 9.57-32.59 g in body weight were analyzed during this study. The overall sex ratio was not significantly different from the expected value of 1:1 (χ2 =2.57, P>0.05, but there was significant difference in the length-frequency distributions between the sexes (P=0.03. The allometric coefficient b for the LWR indicated negative allometric growth (b≈3.00 in males, female and combined sexes. Results further indicated that KF was not significantly different between the sexes (P=0.57. However, the mean WR of R. corsula showed significant differences from 100 for males (P=0.03 and females (P<0.001 in this study, indicating the imbalance habitat with food availability relative to the presence of predators. Conclusions: This study reported the first description of biometric relationships for R. corsula, which would be useful for the sustainable conservation of this rear fishery in Bangladesh and also neighboring countries.

  12. Generalized anxiety disorder and the Hamilton Anxiety Rating Scale in Parkinson's disease Transtorno de ansiedade generalizada e a Escala de Ansiedade de Hamilton na doença de Parkinson

    Directory of Open Access Journals (Sweden)

    Arthur Kummer

    2010-08-01

    Full Text Available Anxiety is common in Parkinson's disease (PD, but studies concerning specific anxiety disorders are scarce. Essential psychometric properties of anxiety rating scales are also lacking. OBJECTIVE: To investigate general anxiety disorder (GAD in PD and psychometric properties of the Hamilton Anxiety Rating Scale (Ham-A. METHOD: Ninety-one PD patients underwent neurological and psychiatric examination, which included the MINI-Plus, the Ham-A and the Hamilton Depression Rating Scale (Ham-D. RESULTS: GAD was present in 30.8% of PD patients. Patients with GAD had longer disease duration (p=0.044 and were in use of higher doses of levodopa (p=0.034. They also tended to have more motor fluctuations and dyskinesias. The group with GAD scored higher in Ham-A (pAnsiedade é comum na doença de Parkinson (DP, mas estudos sobre transtornos de ansiedade específicos são ainda escassos. Faltam também estudos sobre propriedades psicométricas essenciais das escalas de ansiedade. OBJETIVO: Investigar o transtorno de ansiedade generalizada (TAG na DP e propriedades psicométricas da Escala de Ansiedade de Hamilton (Ham-A. MÉTODO: Noventa e um pacientes com DP se submeteram a exames neurológico e psiquiátrico, que incluiu o MINI-Plus, a Ham-A e a Escala de Depressão de Hamilton (Ham-D. RESULTADOS: TAG esteve presente em 30,8% dos participantes. Pacientes com TAG tinham maior duração de doença (p=0,044 e estavam em uso de maiores doses de levodopa (p=0,034. Também havia uma tendência desses pacientes terem mais flutuações motoras e discinesias. O grupo com TAG pontuou mais alto na Ham-A (p<0,001, nas subescalas somática (p<0,001 e psíquica da Ham-A (p<0,001, e na Ham-D (p=0,004. A Ham-A mostrou boa consistência interna (alfa de Cronbach=0,893 e um ponto de corte de 10/11 é sugerido para triar o TAG. CONCLUSÃO: TAG é freqüente na DP e a Ham-A pode ser um instrumento útil para triar esse transtorno.

  13. Trace Formulae of Characteristic Polynomial and Cayley-Hamilton's Theorem, and Applications to Chiral Perturbation Theory and General Relativity

    International Nuclear Information System (INIS)

    Zhang Honghao; Yan Wenbin; Li Xuesong

    2008-01-01

    By using combinatorics, we give a new proof for the recurrence relations of the characteristic polynomial coefficients, and we further obtain an explicit expression for the generic term of the coefficient sequence, which yields the trace formulae of the Cayley-Hamilton's theorem with all coefficients explicitly given. This implies a byproduct, a complete expression for the determinant of any finite-dimensional matrix in terms of the traces of its successive powers. And we discuss some of their applications to chiral perturbation theory and general relativity

  14. Outbreak of salmonellosis associated with consumption of pulled pork at a church festival - Hamilton County, Ohio, 2010.

    Science.gov (United States)

    2014-01-03

    On June 18, 2010, Hamilton County Public Health (HCPH), a local health department in Ohio, began receiving reports of gastrointestinal illness from persons who attended a church festival held during June 11-13 in a suburban community of Hamilton County. HCPH investigated and confirmed the existence of a foodborne outbreak associated with consumption of pulled pork prepared in a private home and sold at the church festival. Sixty-four attendees with gastroenteritis were identified. Salmonella enterica serotype Typhimurium (Salmonella Typhimurium) was found in stool specimens from three patients; no other pathogen was found. Because the outbreak was identified after the church festival had concluded, the environmental investigation was limited to interviews of food handlers. The primary public health interventions consisted of 1) active surveillance for additional cases of salmonellosis associated with the festival, 2) consultation with the festival organizers and food vendors to ensure the pork product was not resold or consumed elsewhere, 3) education of the festival organizers and food vendors about relevant public health regulations and food safety practices, 4) traceback of the implicated product to the retailer in Indiana, and 5) notification of the Indiana State Department of Health. The results of the investigation call attention to the public health implications of unregulated food service at events such as church festivals, which generally are exempt from public health inspection and licensure in Ohio. Food sold in such environments might place populations at risk for foodborne illness.

  15. Relationship Between the DSM-5 Anxious Distress Specifier and the Hamilton Depression Rating Scale Anxiety/Somatization Factor.

    Science.gov (United States)

    Zimmerman, Mark; Clark, Heather; McGonigal, Patrick; Harris, Lauren; Guzman Holst, Carolina; Martin, Jacob

    2018-02-01

    We examined the association between the Hamilton Depression Scale (HAMD) approach to classifying depressed patients into anxious and nonanxious subgroups and the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) anxious distress specifier subtyping. Two hundred two depressed patients were interviewed with semistructured diagnostic interviews. Patients were rated on the 17-item HAMD and the Hamilton Anxiety Rating Scale and completed the Clinically Useful Anxiety Outcome Scale. Both approaches toward identifying anxiety in depressed patients resulted in most of the patients meeting the anxiety subtype. Both subtyping methods were significantly correlated with clinician-rated and self-report measures of anxiety, and scores on the anxiety scales were higher in the patients who met the anxious subtype. However, DSM-5 anxious distress subtyping was only marginally associated with the HAMD anxiety/somatization factor subtyping approach (k = 0.21), and dimensional scores were only moderately correlated (r = 0.50). These findings indicate that the DSM-5 and HAMD approaches toward identifying an anxious subtype of depression are not interchangeable.

  16. Investigations of groundwater system and simulation of regional groundwater flow for North Penn Area 7 Superfund site, Montgomery County, Pennsylvania

    Science.gov (United States)

    Senior, Lisa A.; Goode, Daniel J.

    2013-01-01

    Groundwater in the vicinity of several industrial facilities in Upper Gwynedd Township and vicinity, Montgomery County, in southeast Pennsylvania has been shown to be contaminated with volatile organic compounds (VOCs), the most common of which is the solvent trichloroethylene (TCE). The 2-square-mile area was placed on the National Priorities List as the North Penn Area 7 Superfund site by the U.S. Environmental Protection Agency (USEPA) in 1989. The U.S. Geological Survey (USGS) conducted geophysical logging, aquifer testing, and water-level monitoring, and measured streamflows in and near North Penn Area 7 from fall 2000 through fall 2006 in a technical assistance study for the USEPA to develop an understanding of the hydrogeologic framework in the area as part of the USEPA Remedial Investigation. In addition, the USGS developed a groundwater-flow computer model based on the hydrogeologic framework to simulate regional groundwater flow and to estimate directions of groundwater flow and pathways of groundwater contaminants. The study area is underlain by Triassic- and Jurassic-age sandstones and shales of the Lockatong Formation and Brunswick Group in the Mesozoic Newark Basin. Regionally, these rocks strike northeast and dip to the northwest. The sequence of rocks form a fractured-sedimentary-rock aquifer that acts as a set of confined to partially confined layers of differing permeabilities. Depth to competent bedrock typically is less than 20 ft below land surface. The aquifer layers are recharged locally by precipitation and discharge locally to streams. The general configuration of the potentiometric surface in the aquifer is similar to topography, except in areas affected by pumping. The headwaters of Wissahickon Creek are nearby, and the stream flows southwest, parallel to strike, to bisect North Penn Area 7. Groundwater is pumped in the vicinity of North Penn Area 7 for industrial use, public supply, and residential supply. Results of field investigations

  17. Calculation of blade-data for the Hamilton standard structural analysis of the composite blade for the 18 meter diameter rotor and a comparison with FFA-calculation

    Energy Technology Data Exchange (ETDEWEB)

    Lundemo, C

    1979-04-01

    Section property data for the composite blade manufactured by Karlskronavarvet was calculated for the analysis performed by Hamilton Standard. The HS investigation was carried out for various operating conditions, including dynamic response loads, stresses, frequencies and dynamic stability. The Hamilton Standard results has been compared with the FFA (The Aeronautical Research Institute of Sweden) calculation. The results show that the stresses and moments calculated by HS never exceed the allowable levels for the hinged hub configuration. The natural frequencies seem to agree quite well with the measured frequencies. In the input data of the Hamilton Standard dynamic response analysis a too far aft position of the cordwise center of gravity of the outher third of the blade was used. Correct position will give lower stresses.

  18. A meta-analytic comparison of the Beck Depression Inventory and the Hamilton Rating Scale for Depression as measures of treatment outcome.

    Science.gov (United States)

    Edwards, B C; Lambert, M J; Moran, P W; McCully, T; Smith, K C; Ellingson, A G

    1984-05-01

    Some clinicians have considered the Beck Depression Inventory, a self-rating scale, too reactive to patient halo effects and, therefore, a liberal measure of treatment outcome. On the other hand, interviewer-rating scales, like the Hamilton Rating Scale for Depression have been viewed as more conservative measures of treatment gain. Studies which compared the Beck Depression Inventory to the Hamilton Rating Scale, as dependent measures, were reviewed for the purpose of determining if the scales provided comparable data for assessing treatment effects. The use of meta-analysis techniques resulted in a comparison of effect sizes which indicated that the Beck Depression Inventory was significantly less liberal than the Hamilton Rating Scale for Depression. The implications of these results for selecting outcome measures and the application of meta-analysis techniques for comparing dependent measures are discussed.

  19. Occurrence of Selected Pharmaceuticals, Personal-Care Products, Organic Wastewater Compounds, and Pesticides in the Lower Tallapoosa River Watershed near Montgomery, Alabama, 2005

    Science.gov (United States)

    Oblinger, Carolyn J.; Gill, Amy C.; McPherson, Ann K.; Meyer, Michael T.; Furlong, Edward T.

    2007-01-01

    Synthetic and natural organic compounds derived from agricultural operations, residential development, and treated and untreated sanitary and industrial wastewater discharges can contribute contaminants to surface and ground waters. To determine the occurrence of these compounds in the lower Tallapoosa River watershed, Alabama, new laboratory methods were used that can detect human and veterinary antibiotics; pharmaceuticals; and compounds found in personal-care products, food additives, detergents and their metabolites, plasticizers, and other industrial and household products in the environment. Well-established methods for detecting 47 pesticides and 19 pesticide degradates also were used. In all, 186 different compounds were analyzed by using four analytical methods. The lower Tallapoosa River serves as the water-supply source for more than 100,000 customers of the Montgomery Water Works and Sanitary Sewer Board. Source-water protection is a high priority for the Board, which is responsible for providing safe drinking water. The U.S. Geological Survey, in cooperation with the Montgomery Water Works and Sanitary Sewer Board, conducted this study to provide baseline data that could be used to assess the effects of agriculture and residential development on the occurrence of selected organic compounds in the lower Tallapoosa River watershed. Twenty samples were collected at 10 sites on the Tallapoosa River and its tributaries. Ten samples were collected in April 2005 during high base streamflow, and 10 samples were collected in October 2005 when base streamflow was low. Thirty-two of 186 compounds were detected in the lower Tallapoosa River watershed. Thirteen compounds, including atrazine, 2-chloro-4-isopropylamino-6-amino-s-triazine (CIAT), hexazinone, metalaxyl, metolachlor, prometryn, prometon, simazine, azithromycin, oxytetracycline, sulfamethoxazole, trimethoprim, and tylosin, had measurable concentrations above their laboratory reporting levels

  20. Convergence of a semi-discretization scheme for the Hamilton-Jacobi equation: A new approach with the adjoint method

    KAUST Repository

    Cagnetti, Filippo

    2013-11-01

    We consider a numerical scheme for the one dimensional time dependent Hamilton-Jacobi equation in the periodic setting. This scheme consists in a semi-discretization using monotone approximations of the Hamiltonian in the spacial variable. From classical viscosity solution theory, these schemes are known to converge. In this paper we present a new approach to the study of the rate of convergence of the approximations based on the nonlinear adjoint method recently introduced by L.C. Evans. We estimate the rate of convergence for convex Hamiltonians and recover the O(h) convergence rate in terms of the L∞ norm and O(h) in terms of the L1 norm, where h is the size of the spacial grid. We discuss also possible generalizations to higher dimensional problems and present several other additional estimates. The special case of quadratic Hamiltonians is considered in detail in the end of the paper. © 2013 IMACS.

  1. Mathematical methods in the solution of the the Hamilton-Darwin and the Takagi-Taupin equations

    International Nuclear Information System (INIS)

    Werner, S.A.; Berliner, R.R.; Arif, M.; Missouri Univ., Columbia

    1986-01-01

    The diffraction of neutrons by a single crystal is intrinsically a multiple scattering problem. For an ideally imperfect mosaic crystal the Hamilton-Darwin transfer equations describe the coupling of the incident and diffracted beams; whereas, for a perfect crystal one must use the dynamical theory of diffraction, which can be recast in the form of two coupled partial differential equations commonly referred to as the Takagi-Taupin equations. From a mathematical point of view these two problems are equivalent, although the physical manifestations of the solutions are quite different. For the occasion of Professor Shull's seventieth birthday celebration, we bring together in this paper some of the mathematical techniques which we have found useful in elucidating the subtleties of the Bragg diffraction of neutron by crystals. (orig.)

  2. Convergence of a semi-discretization scheme for the Hamilton-Jacobi equation: A new approach with the adjoint method

    KAUST Repository

    Cagnetti, Filippo; Gomes, Diogo A.; Tran, Hung Vinh

    2013-01-01

    We consider a numerical scheme for the one dimensional time dependent Hamilton-Jacobi equation in the periodic setting. This scheme consists in a semi-discretization using monotone approximations of the Hamiltonian in the spacial variable. From classical viscosity solution theory, these schemes are known to converge. In this paper we present a new approach to the study of the rate of convergence of the approximations based on the nonlinear adjoint method recently introduced by L.C. Evans. We estimate the rate of convergence for convex Hamiltonians and recover the O(h) convergence rate in terms of the L∞ norm and O(h) in terms of the L1 norm, where h is the size of the spacial grid. We discuss also possible generalizations to higher dimensional problems and present several other additional estimates. The special case of quadratic Hamiltonians is considered in detail in the end of the paper. © 2013 IMACS.

  3. Hamilton-Jacobi theory for continuation of magnetic field across a toroidal surface supporting a plasma pressure discontinuity

    International Nuclear Information System (INIS)

    McGann, M.; Hudson, S.R.; Dewar, R.L.; Nessi, G. von

    2010-01-01

    The vanishing of the divergence of the total stress tensor (magnetic plus kinetic) in a neighborhood of an equilibrium plasma containing a toroidal surface of discontinuity gives boundary and jump conditions that strongly constrain allowable continuations of the magnetic field across the surface. The boundary conditions allow the magnetic fields on either side of the discontinuity surface to be described by surface magnetic potentials, reducing the continuation problem to that of solving a Hamilton-Jacobi equation. The characteristics of this equation obey Hamiltonian equations of motion, and a necessary condition for the existence of a continued field across a general toroidal surface is that there exist invariant tori in the phase space of this Hamiltonian system. It is argued from the Birkhoff theorem that existence of such an invariant torus is also, in general, sufficient for continuation to be possible. An important corollary is that the rotational transform of the continued field on a surface of discontinuity must, generically, be irrational.

  4. Risk and efficacy of human-enabled interspecific hybridization for climate-change adaptation: Response to Hamilton and Miller (2016)

    Science.gov (United States)

    Kovach, Ryan P.; Luikart, Gordon; Lowe, Winsor H.; Boyer, Matthew C.; Muhlfeld, Clint C.

    2016-01-01

    Hamilton and Miller (2016) provide an interesting and provocative discussion of how hybridization and introgression can promote evolutionary potential in the face of climate change. They argue that hybridization—mating between individuals from genetically distinct populations—can alleviate inbreeding depression and promote adaptive introgression and evolutionary rescue. We agree that deliberate intraspecific hybridization (mating between individuals of the same species) is an underused management tool for increasing fitness in inbred populations (i.e., genetic rescue; Frankham 2015; Whiteley et al. 2015). The potential risks and benefits of assisted gene flow have been discussed in the literature, and an emerging consensus suggests that mating between populations isolated for approximately 50–100 generations can benefit fitness, often with a minor risk of outbreeding depression (Frankham et al. 2011; Aitken & Whitlock 2013; Allendorf et al. 2013).

  5. Variation in PAH inputs and microbial community in surface sediments of Hamilton Harbour: Implications to remediation and monitoring

    International Nuclear Information System (INIS)

    Slater, G.F.; Cowie, B.R.; Harper, N.; Droppo, I.G.

    2008-01-01

    Variations in concentrations of polycyclic aromatic hydrocarbons (PAHs) and microbial community indicators were investigated in representative highly contaminated and less contaminated surface sediment sites of Hamilton Harbour. Inputs of PAH to the upper 3 cm of sediments up to four times the average upper sediment concentrations were observed. Associated PAH fingerprint profiles indicated that the source was consistent with the PAH source to the industrial region of the harbour. Increased PAH loadings were associated with decreased bacterial populations as indicated by phospholipid fatty acid (PLFA) concentrations. However, relatively minor impacts on overall community composition were indicated. Porewater methane concentrations and isotopic data indicated a difference in the occurrence of methane oxidation between the two sites. This study confirms temporally limited transport of contaminants from highly impacted regions as a vector for contaminants within the harbour and the impact on microbial carbon cycling and bed stability. - Variations in PAH inputs to harbour sediments have implications to implementation and monitoring of mitigation/remediation efforts

  6. Effect of the refractive index on the hawking temperature: an application of the Hamilton-Jacobi method

    Science.gov (United States)

    Sakalli, I.; Mirekhtiary, S. F.

    2013-10-01

    Hawking radiation of a non-asymptotically flat 4-dimensional spherically symmetric and static dilatonic black hole (BH) via the Hamilton-Jacobi (HJ) method is studied. In addition to the naive coordinates, we use four more different coordinate systems that are well-behaved at the horizon. Except for the isotropic coordinates, direct computation by the HJ method leads to the standard Hawking temperature for all coordinate systems. The isotropic coordinates allow extracting the index of refraction from the Fermat metric. It is explicitly shown that the index of refraction determines the value of the tunneling rate and its natural consequence, the Hawking temperature. The isotropic coordinates in the conventional HJ method produce a wrong result for the temperature of the linear dilaton. Here, we explain how this discrepancy can be resolved by regularizing the integral possessing a pole at the horizon.

  7. Effect of the refractive index on the hawking temperature: an application of the Hamilton-Jacobi method

    Energy Technology Data Exchange (ETDEWEB)

    Sakalli, I., E-mail: izzet.sakalli@emu.edu.tr; Mirekhtiary, S. F., E-mail: fatemeh.mirekhtiary@emu.edu.tr [Eastern Mediterranean University G. Magosa, Department of Physics (Turkey)

    2013-10-15

    Hawking radiation of a non-asymptotically flat 4-dimensional spherically symmetric and static dilatonic black hole (BH) via the Hamilton-Jacobi (HJ) method is studied. In addition to the naive coordinates, we use four more different coordinate systems that are well-behaved at the horizon. Except for the isotropic coordinates, direct computation by the HJ method leads to the standard Hawking temperature for all coordinate systems. The isotropic coordinates allow extracting the index of refraction from the Fermat metric. It is explicitly shown that the index of refraction determines the value of the tunneling rate and its natural consequence, the Hawking temperature. The isotropic coordinates in the conventional HJ method produce a wrong result for the temperature of the linear dilaton. Here, we explain how this discrepancy can be resolved by regularizing the integral possessing a pole at the horizon.

  8. Comments on 'Origin of British and Irish mammals: disparate post-glacial colonisation and species introductions' by W.I. Montgomery, J. Provan, A.M. McCabe, and D.W. Yalden

    Science.gov (United States)

    Edwards, Ceiridwen J.

    2014-12-01

    Montgomery et al.'s recent paper in QSR (2014; vol. 98: 144-165) is a most welcome addition to the ongoing research into the origins of Irish mammals. In their Table 1, the authors have used "calibrated carbon dating, comparable stratigraphy and historical records … to establish the earliest known time of arrival of a species in […] Ireland […] where relevant, the latest record of a mammal species [was] used to establish the earliest date after which it was extinct". It is assumed that the dates mentioned in this table are, therefore, calibrated. However, this is very unclear - when dates generated by the Irish Quaternary Fauna project (Woodman et al., 1997) are compared with those used by Montgomery et al. (2014), the earliest recorded dates of Mountain/Irish hare, Irish stoat, lynx and pine marten seem to be direct uncalibrated dates. It is also unclear whether the earliest and latest records of each species relate to all published data available at the time of writing. Even if only consulting those dates generated by Woodman et al. (1997), there are older earliest records for Arctic Fox, Collared lemming and grey wolf. In addition, Montgomery et al. (2014) do not seem to have included early radiocarbon dates for giant deer, reindeer and red deer (Woodman et al., 1997; Carden et al., 2012), or any of the recent radiocarbon dates for brown bear (Edwards et al., 2011), despite reference to these papers.

  9. Symptoms of anxiety in depression: assessment of item performance of the Hamilton Anxiety Rating Scale in patients with depression.

    Science.gov (United States)

    Vaccarino, Anthony L; Evans, Kenneth R; Sills, Terrence L; Kalali, Amir H

    2008-01-01

    Although diagnostically dissociable, anxiety is strongly co-morbid with depression. To examine further the clinical symptoms of anxiety in major depressive disorder (MDD), a non-parametric item response analysis on "blinded" data from four pharmaceutical company clinical trials was performed on the Hamilton Anxiety Rating Scale (HAMA) across levels of depressive severity. The severity of depressive symptoms was assessed using the 17-item Hamilton Depression Rating Scale (HAMD). HAMA and HAMD measures were supplied for each patient on each of two post-screen visits (n=1,668 observations). Option characteristic curves were generated for all 14 HAMA items to determine the probability of scoring a particular option on the HAMA in relation to the total HAMD score. Additional analyses were conducted using Pearson's product-moment correlations. Results showed that anxiety-related symptomatology generally increased as a function of overall depressive severity, though there were clear differences between individual anxiety symptoms in their relationship with depressive severity. In particular, anxious mood, tension, insomnia, difficulties in concentration and memory, and depressed mood were found to discriminate over the full range of HAMD scores, increasing continuously with increases in depressive severity. By contrast, many somatic-related symptoms, including muscular, sensory, cardiovascular, respiratory, gastro-intestinal, and genito-urinary were manifested primarily at higher levels of depression and did not discriminate well at lower HAMD scores. These results demonstrate anxiety as a core feature of depression, and the relationship between anxiety-related symptoms and depression should be considered in the assessment of depression and evaluation of treatment strategies and outcome.

  10. 'Morals can not be drawn from facts but guidance may be': the early life of W.D. Hamilton's theory of inclusive fitness.

    Science.gov (United States)

    Swenson, Sarah A

    2015-12-01

    W.D. Hamilton's theory of inclusive fitness saw the evolution of altruism from the point of view of the gene. It was at heart a theory of limits, redefining altruistic behaviours as ultimately selfish. This theory inspired two controversial texts published almost in tandem, E.O. Wilson's Sociobiology: The New Synthesis (1975) and Richard Dawkins's The Selfish Gene (1976). When Wilson and Dawkins were attacked for their evolutionary interpretations of human societies, they claimed a distinction between reporting what is and declaring what ought to be. Can the history of sociobiological theories be so easily separated from its sociopolitical context? This paper draws upon unpublished materials from the 1960s and early 1970s and documents some of the ways in which Hamilton saw his research as contributing to contemporary concerns. It pays special attention to the 1969 Man and Beast Smithsonian Institution symposium in order to explore the extent to which Hamilton intended his theory to be merely descriptive versus prescriptive. From this, we may see that Hamilton was deeply concerned about the political chaos he perceived in the world around him, and hoped to arrive at a level of self-understanding through science that could inform a new social order.

  11. Negative correlation between nuptial throat colour and blood parasite load in male European green lizards supports the Hamilton-Zuk hypothesis

    Science.gov (United States)

    Molnár, Orsolya; Bajer, Katalin; Mészáros, Boglárka; Török, János; Herczeg, Gábor

    2013-06-01

    During female mate choice, conspicuous male sexual signals are used to infer male quality and choose the best sire for the offspring. The theory of parasite-mediated sexual selection (Hamilton-Zuk hypothesis) presumes that parasite infection can influence the elaboration of sexual signals: resistant individuals can invest more energy into signal expression and thus advertise their individual quality through signal intensity. By preferring these males, females can provide resistance genes for their offspring. Previous research showed that nuptial throat colour of male European green lizard, Lacerta viridis, plays a role in both inter- and intrasexual selections as a condition-dependent multiple signalling system. The aim of this study was to test the predictions of the Hamilton-Zuk hypothesis on male European green lizards. By blood sampling 30 adult males during the reproductive season, we found members of the Haemogregarinidae family in all but one individual (prevalence = 96 %). The infection intensity showed strong negative correlation with the throat and belly colour brightness in line with the predictions of the Hamilton-Zuk hypothesis. In addition, we found other correlations between infection intensity and other fitness-related traits, suggesting that parasite load has a remarkable effect on individual fitness. This study shows that throat patch colour of the European green lizards not only is a multiple signalling system but also possibly acts as an honest sexual signal of health state in accordance with the Hamilton-Zuk hypothesis.

  12. Frailty index of deficit accumulation and falls: data from the Global Longitudinal Study of Osteoporosis in Women (GLOW) Hamilton cohort.

    Science.gov (United States)

    Li, Guowei; Ioannidis, George; Pickard, Laura; Kennedy, Courtney; Papaioannou, Alexandra; Thabane, Lehana; Adachi, Jonathan D

    2014-05-29

    To investigate the association between frailty index (FI) of deficit accumulation and risk of falls, fractures, death and overnight hospitalizations in women aged 55 years and older. The data were from the Global Longitudinal Study of Osteoporosis in Women (GLOW) Hamilton Cohort. In this 3-year longitudinal, observational cohort study, women (N=3,985) aged ≥ 55 years were enrolled between May 2008 and March 2009 in Hamilton, Canada. A FI including co-morbidities, activities of daily living, symptoms and signs, and healthcare utilization was constructed using 34 health deficits at baseline. Relationship between the FI and falls, fractures, death and overnight hospitalizations was examined. The FI was significantly associated with age, with a mean rate of deficit accumulation across baseline age of 0.004 or 0.021 (on a log scale) per year. During the third year of follow-up, 1,068 (31.89%) women reported at least one fall. Each increment of 0.01 on the FI was associated with a significantly increased risk of falls during the third year of follow-up (odds ratio [OR]: 1.02, 95% confidence interval [CI]: 1.02-1.03). The area under the curve (AUC) of the predictive model was 0.69 (95% CI: 0.67-0.71). Results of subgroup and sensitivity analyses indicated the relationship between the FI and risk of falls was robust, while bootstrap analysis judged its internal validation. The FI was significantly related to fractures (hazard ratio [HR]: 1.02, 95% CI: 1.01-1.03), death (OR: 1.05, 95% CI: 1.03-1.06) during the 3-year follow-up period and overnight hospitalizations (incidence rate ratio [IRR]: 1.02, 95% CI: 1.02-1.03) for an increase of 0.01 on the FI during the third year of follow-up. Measured by per standard deviation (SD) increment of the FI, the ORs were 1.21 and 1.40 for falls and death respectively, while the HR was 1.17 for fractures and the IRR was 1.18 for overnight hospitalizations respectively. The FI of deficit accumulation increased with chronological age

  13. The influence of magnetic field on the spatial orientation in zebrafish Danio rerio (Hamilton and roach Rutilus rutilus (L.

    Directory of Open Access Journals (Sweden)

    Anastasia A. Batrakova

    2015-11-01

    Full Text Available Known, that some teleostei can perceive the geomagnetic field (GMF. However, the information about magnetosensitivity in Cyprinidae fish from artificial and natural habitats is obscure. We have registered preferred directions in Danio rerio (Hamilton from aquaria-cultivated line exposed to the natural GMF, 180 degrees reversal of horizontal GMF component, 180 degrees reversal of vertical GMF component, 180 degrees reversal of both vertical and horizontal GMF components and 90 degrees clockwise turn of horizontal GMF component. We also registered the preferred directions in Rutilus rutilus (L. from Rybinsk reservoir exposed to the natural GMF and 90 degrees clockwise turn of horizontal GMF component. It was found that zebrafish prefer two opposite directions towards east and west in the natural GMF. When the horizontal component of GMF was turned 90 degrees clockwise D. rerio prefer two opposite directions towards north and south. The possible reason of bimodality in zebrafish’s preferred directions distributions is discussed. The only direction towards east-north-east observed in roach under the natural GMF. This direction coincided with the way from the place of capture to the streamflow part of Rybinsk reservoir. And it was changed by south-south-east direction when turned the horizontal component of GMF 90 degrees clockwise. The possible reason of the choosing directions by fish with GMF is discussed.

  14. Axisymmetric black holes allowing for separation of variables in the Klein-Gordon and Hamilton-Jacobi equations

    Science.gov (United States)

    Konoplya, R. A.; Stuchlík, Z.; Zhidenko, A.

    2018-04-01

    We determine the class of axisymmetric and asymptotically flat black-hole spacetimes for which the test Klein-Gordon and Hamilton-Jacobi equations allow for the separation of variables. The known Kerr, Kerr-Newman, Kerr-Sen and some other black-hole metrics in various theories of gravity are within the class of spacetimes described here. It is shown that although the black-hole metric in the Einstein-dilaton-Gauss-Bonnet theory does not allow for the separation of variables (at least in the considered coordinates), for a number of applications it can be effectively approximated by a metric within the above class. This gives us some hope that the class of spacetimes described here may be not only generic for the known solutions allowing for the separation of variables, but also a good approximation for a broader class of metrics, which does not admit such separation. Finally, the generic form of the axisymmetric metric is expanded in the radial direction in terms of the continued fractions and the connection with other black-hole parametrizations is discussed.

  15. A new algorithm to find fuzzy Hamilton cycle in a fuzzy network using adjacency matrix and minimum vertex degree.

    Science.gov (United States)

    Nagoor Gani, A; Latha, S R

    2016-01-01

    A Hamiltonian cycle in a graph is a cycle that visits each node/vertex exactly once. A graph containing a Hamiltonian cycle is called a Hamiltonian graph. There have been several researches to find the number of Hamiltonian cycles of a Hamilton graph. As the number of vertices and edges grow, it becomes very difficult to keep track of all the different ways through which the vertices are connected. Hence, analysis of large graphs can be efficiently done with the assistance of a computer system that interprets graphs as matrices. And, of course, a good and well written algorithm will expedite the analysis even faster. The most convenient way to quickly test whether there is an edge between two vertices is to represent graphs using adjacent matrices. In this paper, a new algorithm is proposed to find fuzzy Hamiltonian cycle using adjacency matrix and the degree of the vertices of a fuzzy graph. A fuzzy graph structure is also modeled to illustrate the proposed algorithms with the selected air network of Indigo airlines.

  16. Two new species of philometrid nematodes (Nematoda: Philometridae) in Epinephelus coioides (Hamilton, 1822) from the South Bali Sea, Indonesia.

    Science.gov (United States)

    Dewi, Kartika; Palm, Harry W

    2013-01-25

    Based on light and scanning electron microscopy, two new species of philometrid nematodes, Spirophilometra endangae sp. nov. and Philometra epinepheli sp. nov. (Nematoda: Dracunculoidea: Philometridae) are described from Epinephelus coioides (Hamilton, 1822) (Perciformes: Serranidae) from the South Bali Sea, Indonesia. Spirophilometra endangae sp. nov. was isolated from the fins of E. coioides. The new species can be distinguished from the most closely related S. eichleri Parukhin, 1971 by a larger total body length and the site of infection in the host. The new species differs from S. centropomi (Caballero, 1974) also in the larger body size of the gravid females and the site of infection in the host. S. en-dangae sp. nov. differs from S. pacifica (Moravec, Santana-Pineros, Gonzales-Solis & Torres-Huerta, 2007) in the struc-ture and arrangement of the spines on the middle part of the body, the infection site of the worm, the type host and the zoogeographical host distribution. Philometra epinepheli sp. nov. differs from all other Philometra spp. congeners so far recorded from Ephinepelus groupers in the total body length and the site of infection. This is the first opercula-infecting species of Philometra described from the fish family Serranidae.

  17. GRUPO TERAPÊUTICO COM MULHERES COM TRANSTORNOS DE ANSIEDADE: AVALIAÇÃO PELA ESCALA DE ANSIEDADE DE HAMILTON

    Directory of Open Access Journals (Sweden)

    ÂNGELA MARIA ALVES E SOUZA

    2008-01-01

    Full Text Available La necesidad de evaluar la asistencia a un grupo de mujeres nos llevó a la aplicación de una escala. Fueron seleccionadas dieciocho usuarias con diagnóstico de trastornos neuróticos, relacionados al estrés y somato formes. Se aplicó la Escala de Evaluación de Ansiedad de Hamilton (HAM-A con el objetivo de verificar el nivel de ansiedad antes y después de empezar las sesiones grupales. Realizamos 16 sesiones semanales, con desarrollo de técnicas de relajación y arte terapia, y como referencial la Terapia de Gestalt de corta duración. Después de las secciones de grupo, el nivel de ansiedad de las mujeres acompañadas a través de abordaje grupal, tuvo reducción significativa en lo que se refiere a los síntomas que habían aparecido como características determinantes para su sufrimiento psíquico.

  18. Performance on the Hamilton search task, and the influence of lateralization, in captive orange-winged Amazon parrots (Amazona amazonica).

    Science.gov (United States)

    Cussen, Victoria A; Mench, Joy A

    2014-07-01

    Psittacines are generally considered to possess cognitive abilities comparable to those of primates. Most psittacine research has evaluated performance on standardized complex cognition tasks, but studies of basic cognitive processes are limited. We tested orange-winged Amazon parrots (Amazona amazonica) on a spatial foraging assessment, the Hamilton search task. This task is a standardized test used in human and non-human primate studies. It has multiple phases, which require trial and error learning, learning set breaking, and spatial memory. We investigated search strategies used to complete the task, cognitive flexibility, and long-term memory for the task. We also assessed the effects of individual strength of motor lateralization (foot preference) and sex on task performance. Almost all (92%) of the parrots acquired the task. All had significant foot preferences, with 69% preferring their left foot, and showed side preferences contralateral to their preferred limb during location selection. The parrots were able to alter their search strategies when reward contingencies changed, demonstrating cognitive flexibility. They were also able to remember the task over a 6-month period. Lateralization had a significant influence on learning set acquisition but no effect on cognitive flexibility. There were no sex differences. To our knowledge, this is the first cognitive study using this particular species and one of the few studies of cognitive abilities in any Neotropical parrot species.

  19. Psychometric properties of responses by clinicians and older adults to a 6-item Hebrew version of the Hamilton Depression Rating Scale (HAM-D6)

    DEFF Research Database (Denmark)

    Bachner, Yaacov G; O'Rourke, Norm; Goldfracht, Margalit

    2013-01-01

    The Hamilton Depression Rating Scale (HAM-D) is commonly used as a screening instrument, as a continuous measure of change in depressive symptoms over time, and as a means to compare the relative efficacy of treatments. Among several abridged versions, the 6-item HAM-D6 is used most widely in lar...... degree because of its good psychometric properties. The current study compares both self-report and clinician-rated versions of the Hebrew version of this scale....

  20. Variations in Sense of Place Across Immigrant Status and Gender in Hamilton, Ontario; Saskatoon, Saskatchewan; and, Charlottetown, Prince Edward Island, Canada.

    Science.gov (United States)

    Gallina, Melissa; Williams, Allison

    Past research in Hamilton, Ontario has found that age and longevity of residence are positively associated with evaluations of sense of place (SoP); further, evaluations of SoP between immigrants and Canadian-born individuals have shown no clear pattern (Williams et al. 2010; Williams and Kitchen 2012). This paper builds on this work by further examining evaluations of SoP among both immigrants and Canadian-born residents and across gender in Hamilton, while expanding the study to two other small-to-medium sized cities: Saskatoon, Saskatchewan and, Charlottetown, Prince Edward Island. This paper has two objectives: (1) to establish measures of SoP across immigrant status and gender in Hamilton, Saskatoon, and Charlottetown; and, (2) to determine how SoP varies according to immigrant status, length of residence in Canada, age, income, and neighbourhood length of residence across the three city sites. Telephone survey data (n = 1,132) was used to compare evaluations of SoP across various groups and to construct an ordered logistic regression model for SoP. Results suggest that immigrants tended to rate their SoP lower than their Canadian-born counterparts. Hamilton residents were found to rate their SoP lowest, followed by Saskatoon residents and, finally, Charlottetown residents. Younger individuals, those with lower income levels, and those with shorter neighbourhood residency in the cities concerned were more likely to have lower evaluations of SoP. This research suggests that greater attention is needed to nurture immigrants' connection with their new home.

  1. BASEMAP, MONTGOMERY COUNTY, VIRGINIA, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — FEMA Framework Basemap datasets comprise six of the seven FGDC themes of geospatial data that are used by most GIS applications (Note: the seventh framework theme,...

  2. HYDRAULICS, MONTGOMERY COUNTY, ALABAMA, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Recent developments in digital terrain and geospatial database management technology make it possible to protect this investment for existing and future projects to...

  3. FLOODPLAIN, Montgomery COUNTY, VIRGINIA, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

  4. Spatial analysis of air pollution and childhood asthma in Hamilton, Canada: comparing exposure methods in sensitive subgroups

    Directory of Open Access Journals (Sweden)

    Arain Altaf

    2009-04-01

    Full Text Available Abstract Background Variations in air pollution exposure within a community may be associated with asthma prevalence. However, studies conducted to date have produced inconsistent results, possibly due to errors in measurement of the exposures. Methods A standardized asthma survey was administered to children in grades one and eight in Hamilton, Canada, in 1994–95 (N ~1467. Exposure to air pollution was estimated in four ways: (1 distance from roadways; (2 interpolated surfaces for ozone, sulfur dioxide, particulate matter and nitrous oxides from seven to nine governmental monitoring stations; (3 a kriged nitrogen dioxide (NO2 surface based on a network of 100 passive NO2 monitors; and (4 a land use regression (LUR model derived from the same monitoring network. Logistic regressions were used to test associations between asthma and air pollution, controlling for variables including neighbourhood income, dwelling value, state of housing, a deprivation index and smoking. Results There were no significant associations between any of the exposure estimates and asthma in the whole population, but large effects were detected the subgroup of children without hayfever (predominately in girls. The most robust effects were observed for the association of asthma without hayfever and NO2LUR OR = 1.86 (95%CI, 1.59–2.16 in all girls and OR = 2.98 (95%CI, 0.98–9.06 for older girls, over an interquartile range increase and controlling for confounders. Conclusion Our findings indicate that traffic-related pollutants, such as NO2, are associated with asthma without overt evidence of other atopic disorders among female children living in a medium-sized Canadian city. The effects were sensitive to the method of exposure estimation. More refined exposure models produced the most robust associations.

  5. Hamiltonian theory of wave and particle in quantum mechanics 2. Hamilton-Jacobi theory and particle back-reaction

    International Nuclear Information System (INIS)

    Holland, P.

    2001-01-01

    Pursuing the Hamiltonian formulation of the De Broglie-Bohm (deBB) theory presented in the preceding paper, the Hamilton-Jacobi (HJ) theory of the wave-particle system is developed. It is shown how to derive a HJ equation for the particle, which enables trajectories to be computed algebraically using Jacobi's method. Using Liouville's equation in the HJ representation it was found the restriction on the Jacobi solutions which implies the quantal distribution. This gives a first method for interpreting the deBB theory in HJ terms. A second method proceeds via an explicit solution of the field+particle HJ equation. Both methods imply that the quantum phase may be interpreted as an incomplete integral. Using these results and those of the first paper it is shown how Schroedinger's equation can be represented in Liouvilian terms, and vice versa. The general theory of canonical transformations that represent quantum unitary transformations is given, and it is shown in principle how the trajectory theory may be expressed in other quantum representations. Using the solution found for the total HJ equation, an explicit solution for the additional field containing a term representing the particle back-reaction is found. The conservation of energy and momentum in the model is established, and weak form of the action-reaction principle is shown to hold. Alternative forms for the Hamiltonian are explored and it is shown that, within this theoretical context, the deBB theory is not unique. The theory potentially provides an alternative way of obtaining the classical limit

  6. Sir William Rowan Hamilton

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 21; Issue 6 ... and in particular of mechanics, over thecenturies since Galileo and Newton, we ... and the remarkableways in which his work paved the way to theconstruction ...

  7. FLOODPLAIN, HAMILTON COUNTY, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

  8. Progress Report on the ISCR Pilot Test Conducted at the Former CCC/USDA Grain Storage Facility in Montgomery City, Missouri, as of April 2013

    Energy Technology Data Exchange (ETDEWEB)

    LaFreniere, Lorraine M. [Argonne National Lab. (ANL), Argonne, IL (United States). Environmental Science Division. Applied Geoscience and Environmental Restoration Program

    2013-06-01

    The Commodity Credit Corporation of the U.S. Department of Agriculture (CCC/USDA) is conducting an environmental investigation at the former CCC/USDA grain storage facility on the county fairgrounds in Montgomery City, Missouri, to evaluate contamination associated with the former use of grain fumigants containing carbon tetrachloride at the site. The CCC/USDA studies have identified carbon tetrachloride in the soils (primarily unconsolidated glacial tills) at concentrations that exceed the U.S. Environmental Protection Agency (EPA) regional screening level (RSL) values for this compound in residential soils (610 μg/kg) but are below the corresponding RSL for industrial soils (3,000 μg/kg). Concentrations of carbon tetrachloride greater than the EPA maximum contaminant level (MCL; 5.0 μg/L) for this contaminant in drinking water were also identified in the shallow groundwater (Argonne 2012). On the basis of these findings, remedial actions are considered necessary to mitigate the present and potential future impacts of the contamination. In cooperation with the Missouri Department of Natural Resources (MDNR), the CCC/USDA has initiated a field-scale pilot test to evaluate an in situ technology for treatment of the carbon tetrachloride contamination. In this approach, a chemical amendment consisting primarily of slow-release organic matter and zero-valent iron is employed to induce oxygen-depleted, chemically reducing conditions in the subsurface. These conditions foster the in situ chemical reduction (ISCR) of carbon tetrachloride and its degradation products (chloroform, methylene chloride, and chloromethane) via both inorganic and biologically mediated processes. The chemical amendment being used, EHC™, was developed by the Adventus Group, Freeport, Illinois, and is now manufactured and distributed by FMC Environmental Solutions, Philadelphia, Pennsylvania. With the approval of the MDNR (2012), the ISCR technology is being tested in two target areas

  9. Escala Hamilton: estudo das características psicométricas em uma amostra do sul do Brasil

    Directory of Open Access Journals (Sweden)

    Manoela Ávila Freire

    2014-12-01

    Full Text Available Objetivo Investigar as características psicométricas de uma versão traduzida da escala, propondo uma Versão Revisada que atenda aos critérios de adaptação transcultural para o contexto brasileiro. Métodos Este estudo incluiu 231 sujeitos – deprimidos (45,5%, bipolares (7,8% e saudáveis (46,7% – que participaram de uma pesquisa epidemiológica no sul do Brasil. A avaliação de transtornos mentais foi realizada por meio da Clinical Interview for DSM-IV (SCID e uma versão traduzida da Escala de Avaliação de Depressão de Hamilton (HAM-D, que habitualmente vem sendo utilizada no país sem estudos de adaptação. Resultados Identificou-se o ponto de corte (9 pontos para discriminar a presença ou não de sintomas de depressão pela análise da curva ROC, resultando em uma sensibilidade e especificidade de 90 e 91%, respectivamente. A validade interna foi investigada pela análise fatorial e consistência dos itens. Dos 17 itens originais, apenas o item que avalia a “consciência do transtorno” não apresentou carga fatorial satisfatória para avaliar depressão geral e foi eliminado; os 16 restantes agruparam-se em cinco dimensões, denominadas: Humor deprimido, Anorexia, Insônia, Somatização e Ansiedade, as quais, com exceção da última, mostraram homogeneidade nos seus construtos (coeficientes alfa entre 0,66 e 0,78. Na análise de conteúdo dos itens, cinco especialistas sugeriram alterações redacionais em sete itens. Conclusão O estudo determina um ponto de corte diferente do original e evidencia características psicométricas favoráveis para a utilização da escala no Brasil.

  10. The time has come to stop rotations for the identification of structures in the Hamilton Depression Scale (HAM-D17)

    DEFF Research Database (Denmark)

    Bech, Per; Csillag, Claudio; Hellström, Lone

    2013-01-01

    Objective: To use principal component analysis (PCA) to test the hypothesis that the items of the Hamilton Depression Scale (HAM-D17) have been selected to reflect depression disability, whereas some of the items are specific for sub-typing depression into typical vs. atypical depression. Method......: Our previous study using exploratory factor analysis on HAM-D17 has been re-analyzed with PCA and the results have been compared to a dataset from another randomized prospective study. Results: PCA showed that the first principal component was a general factor covering depression disability...

  11. "Peintre de Sa Majesté Britannique". Franz Adolph of Freenthal and his portrait of Maximilian Hamilton, Prince-Bishop of Olomouc

    Directory of Open Access Journals (Sweden)

    Suchánek, Pavel

    2012-09-01

    Full Text Available This essay examines the portrait of Maximilian von Hamilton (1714-1776, the last Prince-Bishop of Olomouc/Olmütz, painted between 1769 and 1772 by Franz Adolph of Freenthal (1721-1773, a former painter to the British royal court. The study focuses in turn on three visual motifs in Hamilton's portrait: the rhetorical gestures of the sitter, his attire and the way he is depicted, and the form of presentation and the function of the painting in the ceremonial space of the princely residence. In examining each of these motifs, account is taken of the specific visual conventions applied in this genre, and of the contemporary rules of visual rhetoric. By referencing the classical motif of modesty and moderation from antiquity, Adolph underlined the importance of the ideal of antiquity and with it "natural" speech and behaviour. He attempted to express the spirit of antiquity by comparing contemporary clothing and rhetorical gestures to those of the orators or other public figures of antiquity. In a similar way to contemporary British painters, he thus referenced models taken from antiquity, with the aim of evoking a noble past and representing the ideal of the virtue of antiquity.

  12. Ground-water flow directions and estimation of aquifer hydraulic properties in the lower Great Miami River Buried Valley aquifer system, Hamilton Area, Ohio

    Science.gov (United States)

    Sheets, Rodney A.; Bossenbroek, Karen E.

    2005-01-01

    The Great Miami River Buried Valley Aquifer System is one of the most productive sources of potable water in the Midwest, yielding as much as 3,000 gallons per minute to wells. Many water-supply wells tapping this aquifer system are purposely placed near rivers to take advantage of induced infiltration from the rivers. The City of Hamilton's North Well Field consists of 10 wells near the Great Miami River, all completed in the lower Great Miami River Buried Valley Aquifer System. A well-drilling program and a multiple-well aquifer test were done to investigate ground-water flow directions and to estimate aquifer hydraulic properties in the lower part of the Great Miami River Buried Valley Aquifer System. Descriptions of lithology from 10 well borings indicate varying amounts and thickness of clay or till, and therefore, varying levels of potential aquifer confinement. Borings also indicate that the aquifer properties can change dramatically over relatively short distances. Grain-size analyses indicate an average bulk hydraulic conductivity value of aquifer materials of 240 feet per day; the geometric mean of hydraulic conductivity values of aquifer material was 89 feet per day. Median grain sizes of aquifer material and clay units were 1.3 millimeters and 0.1 millimeters, respectively. Water levels in the Hamilton North Well Field are affected by stream stage in the Great Miami River and barometric pressure. Bank storage in response to stream stage is evident. Results from a multiple-well aquifer test at the well field indicate, as do the lithologic descriptions, that the aquifer is semiconfined in some areas and unconfined in others. Transmissivity and storage coefficient of the semiconfined part of the aquifer were 50,000 feet squared per day and 5x10-4, respectively. The average hydraulic conductivity (450 feet per day) based on the aquifer test is reasonable for glacial outwash but is higher than calculated from grain-size analyses, implying a scale effect

  13. Hamilton Alaistar, The Copts and the West, 1439-1822, The European Discovery of the Egyptian Church, Oxford, Oxford University Press, 2006, 338 p.

    Directory of Open Access Journals (Sweden)

    Aurélien Girard

    2007-07-01

    Full Text Available Dès le titre, le livre annonce son point de vue : il ne s’agit pas d’une histoire des Coptes mais d’une histoire de la découverte par les Européens de l’Église égyptienne. L’auteur, Alaistar Hamilton, a déjà consacré d’importants travaux à l’histoire de l’orientalisme à l’époque moderne. Son étude commence en 1439 lorsque la décision est prise au concile de Florence (1438-1445 d’inviter la première délégation officielle copte en Europe. À cette occasion, des manuscrits coptes et coptes-arabe...

  14. Measuring anxiety in depressed patients: A comparison of the Hamilton anxiety rating scale and the DSM-5 Anxious Distress Specifier Interview.

    Science.gov (United States)

    Zimmerman, Mark; Martin, Jacob; Clark, Heather; McGonigal, Patrick; Harris, Lauren; Holst, Carolina Guzman

    2017-10-01

    DSM-5 included criteria for an anxious distress specifier for major depressive disorder (MDD). In the present report from the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) project we examined whether a measure of the specifier, the DSM-5 Anxious Distress Specifier Interview (DADSI), was as valid as the Hamilton Anxiety Scale (HAMA) as a measure of the severity of anxiety in depressed patients. Two hundred three psychiatric patients with MDD were interviewed by trained diagnostic raters who administered the Structured Clinical Interview for DSM-IV (SCID) supplemented with questions to rate the DADSI, HAMA, and Hamilton Depression Rating Scale (HAMD). The patients completed self-report measures of depression, anxiety, and irritability. Sensitivity to change was examined in 30 patients. The DADSI and HAMA were significantly correlated (r = 0.60, p anxiety than with measures of the other symptom domains. The HAMD was significantly more highly correlated with the HAMA than with the DADSI. For each anxiety disorder, patients with the disorder scored significantly higher on both the DADSI and HAMA than did patients with no current anxiety disorder. A large effect size of treatment was found for both measures (DADSI: d = 1.48; HAMA: d = 1.37). Both the DADSI and HAMA were valid measures of anxiety severity in depressed patients, though the HAMA was more highly confounded with measures of depression than the DADSI. The DADSI is briefer than the HAMA, and may be more feasible to use in clinical practice. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. 75 FR 29700 - Endangered and Threatened Wildlife and Plants; Revised Critical Habitat for the Preble's Meadow...

    Science.gov (United States)

    2010-05-27

    ... projects, these monetary incremental impacts are likely to be small. The incremental impact due to critical... Policy and Directives Management; U.S. Fish and Wildlife Service; 4401 N. Fairfax Drive, Suite 222... and their possible impacts on the species and the proposed critical habitat. (5) How the proposed...

  16. 75 FR 78429 - Endangered and Threatened Wildlife and Plants; Revised Critical Habitat for the Preble's Meadow...

    Science.gov (United States)

    2010-12-15

    ... to June 28, 2010) and requested comments on our draft economic analysis (DEA) (Industrial Economics..., diverse vegetative cover essential to the conservation of PMJM. (3) Comment: One peer reviewer maintained... PMJM in and near human development are not essential to the conservation of the PMJM. We are not...

  17. Pre-treatment factor structures of the Montgomery and Åsberg Depression Rating scale as predictors of response to escitalopram in Indian patients with non-psychotic major depressive disorder.

    Science.gov (United States)

    Basu, Aniruddha; Chadda, Rakesh; Sood, Mamta; Rizwan, S A

    2017-08-01

    Major Depressive Disorder (MDD) is a broad heterogeneous construct resolving into several symptom-clusters by factor analysis. The aim was to find the factor structures of MDD as per Montgomery and Asberg Depression Rating Scale (MADRS) and whether they predict escitalopram response. In a longitudinal study at a tertiary institute in north India, 116 adult out-patients with non-psychotic unipolar MDD were assessed with MADRS before and after treatment with escitalopram (10-20mg) over 6-8 weeks for drug response. For total 116 patients pre-treatment four factor structures of MADRS extracted by principal component analysis with varimax rotation altogether explained a variance of 57%: first factor 'detachment' (concentration difficulty, lassitude, inability to feel); second factor 'psychic anxiety' (suicidal thoughts and inner tension); third 'mood-pessimism' (apparent sadness, reported sadness, pessimistic thoughts) and fourth 'vegetative' (decreased sleep, appetite). Eighty patients (68.9%) who completed the study had mean age 35.37±10.9 yrs, majority were male (57.5%), with mean pre-treatment MADRS score 28.77±5.18 and majority (65%) having moderate severity (MADRS escitalopram. At the end of the treatment there were significant changes in all the 4 factor structures (pescitalopram treatment. Understanding the factor structure is important as they can be important predictor of escitalopram response. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. The Validity of the Different Versions of the Hamilton Depression Scale in Separating Remission Rates of Placebo and Antidepressants in Clinical Trials of Major Depression

    DEFF Research Database (Denmark)

    Kyle, Phillip Raphael; Lemming, Ole Michael; Timmerby, Nina

    2016-01-01

    . The traditional HAM-D17 version was compared with the shorter HAM-D6 and the longer HAM-D21 or HAM-D24 in a fixed-dose placebo-controlled vortioxetine study. Clinical Global Impression of Severity scores were used to establish standardized cutoff scores for remission across each scale. Using these cutoff scores......Our objective was to validate the different versions of the Hamilton Depression Scale (HAM-D) both psychometrically (scalability) and clinically in discriminating antidepressants from placebo in terms of remission rates in an 8-week clinical trial in the acute treatment of major depression...... in the longer HAM-D versions indicated smaller discriminating validity over placebo. The HAM-D6 indicated a dose effect on remission for vortioxetine in both moderate and severe major depression. The brief HAM-D6 was thus found superior to HAM-D17, HAM-D21, and HAM-D24 both in terms of scalability...

  19. Genetic variation of wild and hatchery populations of the catla Indian major carp (Catla catla Hamilton 1822: Cypriniformes, Cyprinidae revealed by RAPD markers

    Directory of Open Access Journals (Sweden)

    S.M. Zakiur Rahman

    2009-01-01

    Full Text Available Genetic variation is a key component for improving a stock through selective breeding programs. Randomly amplified polymorphic DNA (RAPD markers were used to assess genetic variation in three wild population of the catla carp (Catla catla Hamilton 1822 in the Halda, Jamuna and Padma rivers and one hatchery population in Bangladesh. Five decamer random primers were used to amplify RAPD markers from 30 fish from each population. Thirty of the 55 scorable bands were polymorphic, indicating some degree of genetic variation in all the populations. The proportion of polymorphic loci and gene diversity values reflected a relatively higher level of genetic variation in the Halda population. Sixteen of the 30 polymorphic loci showed a significant (p < 0.05, p < 0.01, p < 0.001 departure from homogeneity and the F ST values in the different populations indicated some degree of genetic differentiation in the population pairs. Estimated genetic distances between populations were directly correlated with geographical distances. The unweighted pair group method with averages (UPGMA dendrogram showed two clusters, the Halda population forming one cluster and the other populations the second cluster. Genetic variation of C. catla is a useful trait for developing a good management strategy for maintaining genetic quality of the species.

  20. Validation of Malay Version of Snaith-Hamilton Pleasure Scale: Comparison between Depressed Patients and Healthy Subjects at an Out-Patient Clinic in Malaysia.

    Science.gov (United States)

    Ng, Chong Guan; Chin, Soo Cheng; Yee, Anne Hway Ann; Loh, Huai Seng; Sulaiman, Ahmad Hatim; Sherianne Sook Kuan, Wong; Habil, Mohamed Hussain

    2014-05-01

    The Snaith-Hamilton Pleasure Scale (SHAPS) is a self-assessment scale designed to evaluate anhedonia in various psychiatric disorders. In order to facilitate its use in Malaysian settings, our current study aimed to examine the validity of a Malay-translated version of the SHAPS (SHAPS-M). In this cross-sectional study, a total of 44 depressed patients and 82 healthy subjects were recruited from a university out-patient clinic. All participants were given both the Malay and English versions of the SHAPS, Fawcett-Clark Pleasure Scale (FCPS), General Health Questionnaire 12 (GHQ-12), and the Beck Depression Inventory (BDI) to assess their hedonic state, general mental health condition and levels of depression. The results showed that the SHAPS-M has impressive internal consistency (α = 0.96), concurrent validity and good parallel-form reliability (intraclass coefficient, ICC = 0.65). In addition to demonstrating good psychometric properties, the SHAPS-M is easy to administer. Therefore, it is a valid, reliable, and suitable questionnaire for assessing anhedonia among depressed patients in Malaysia.

  1. Validation of Malay Version of Snaith-Hamilton Pleasure Scale: Comparison between Depressed Patients and Healthy Subjects at an Out-Patient Clinic in Malaysia

    Science.gov (United States)

    NG, Chong Guan; CHIN, Soo Cheng; YEE, Anne Hway Ann; LOH, Huai Seng; SULAIMAN, Ahmad Hatim; Sherianne Sook Kuan, WONG; HABIL, Mohamed Hussain

    2014-01-01

    Background: The Snaith-Hamilton Pleasure Scale (SHAPS) is a self-assessment scale designed to evaluate anhedonia in various psychiatric disorders. In order to facilitate its use in Malaysian settings, our current study aimed to examine the validity of a Malay-translated version of the SHAPS (SHAPS-M). Methods: In this cross-sectional study, a total of 44 depressed patients and 82 healthy subjects were recruited from a university out-patient clinic. All participants were given both the Malay and English versions of the SHAPS, Fawcett-Clark Pleasure Scale (FCPS), General Health Questionnaire 12 (GHQ-12), and the Beck Depression Inventory (BDI) to assess their hedonic state, general mental health condition and levels of depression. Results: The results showed that the SHAPS-M has impressive internal consistency (α = 0.96), concurrent validity and good parallel-form reliability (intraclass coefficient, ICC = 0.65). Conclusion: In addition to demonstrating good psychometric properties, the SHAPS-M is easy to administer. Therefore, it is a valid, reliable, and suitable questionnaire for assessing anhedonia among depressed patients in Malaysia. PMID:25246837

  2. An evaluation of the quick inventory of depressive symptomatology and the hamilton rating scale for depression: a sequenced treatment alternatives to relieve depression trial report.

    Science.gov (United States)

    Rush, A John; Bernstein, Ira H; Trivedi, Madhukar H; Carmody, Thomas J; Wisniewski, Stephen; Mundt, James C; Shores-Wilson, Kathy; Biggs, Melanie M; Woo, Ada; Nierenberg, Andrew A; Fava, Maurizio

    2006-03-15

    Nine DSM-IV-TR criterion symptom domains are evaluated to diagnose major depressive disorder (MDD). The Quick Inventory of Depressive Symptomatology (QIDS) provides an efficient assessment of these domains and is available as a clinician rating (QIDS-C16), a self-report (QIDS-SR16), and in an automated, interactive voice response (IVR) (QIDS-IVR16) telephone system. This report compares the performance of these three versions of the QIDS and the 17-item Hamilton Rating Scale for Depression (HRSD17). Data were acquired at baseline and exit from the first treatment step (citalopram) in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial. Outpatients with nonpsychotic MDD who completed all four ratings within +/-2 days were identified from the first 1500 STAR*D subjects. Both item response theory and classical test theory analyses were conducted. The three methods for obtaining QIDS data produced consistent findings regarding relationships between the nine symptom domains and overall depression, demonstrating interchangeability among the three methods. The HRSD17, while generally satisfactory, rarely utilized the full range of item scores, and evidence suggested multidimensional measurement properties. In nonpsychotic MDD outpatients without overt cognitive impairment, clinician assessment of depression severity using either the QIDS-C16 or HRSD17 may be successfully replaced by either the self-report or IVR version of the QIDS.

  3. Agreement between hopelessness/helplessness and Montgomery-Asberg Depression Rating Scale in healthy individuals and in patients with benign breast disease and breast cancer: a prospective case-control study in Finland.

    Science.gov (United States)

    Eskelinen, Matti; Korhonen, Riika; Selander, Tuomas; Ollonen, Paula

    2015-04-01

    The relation between scoring for hopelessness/helplessness and the Montgomery-Asberg Depression Rating Scale (MADRS) in healthy study subjects (HSS) and in patients with benign breast disease (BBD) and breast cancer (BC) has not been compared in a prospective study. We, therefore, investigated hopelessness and helplessness scores versus the MADRS in 115 patients. In the Kuopio Breast Cancer Study, 115 women with breast symptoms were evaluated for hopelessness and helplessness, and for the MADRS before any diagnostic procedures were carried out. In the self-rating score (SRS), hopelessness/helplessness versus the MADRS were highly significantly positively correlated in the HSS, BBD and BC groups. In the SRS, the weighted kappa values for hopelessness/helplessness versus the MADRS in the HSS, BBD and BC groups were also statistically significant. There was also a significant positive correlation in the examiner-rating score (ERS) for hopelessness versus the MADRS in the HSS, BBD and BC groups and for helplessness versus the MADRS in the HSS, BBD and BC groups. The unweighted kappa values in the ERS for hopelessness versus the MADRS were statistically highly significant for the HSS, BBD and BC groups and those for helplessness versus the MADRS in the HSS and BBD groups were statistically significant. A new finding with clinical relevance in the present work is the agreement between hopelessness/helplessness scores and MADRS in the SRS and ERS. In the breast cancer diagnostic unit, the identification of hopeless/helpless persons is essential in suicide prevention and it is important to assess and treat hopelessness/helplessness even though an individual may report few depressive symptoms. Copyright© 2015 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

  4. An item response theory evaluation of the young mania rating scale and the montgomery-asberg depression rating scale in the systematic treatment enhancement program for bipolar disorder (STEP-BD).

    Science.gov (United States)

    Prisciandaro, James J; Tolliver, Bryan K

    2016-11-15

    The Young Mania Rating Scale (YMRS) and Montgomery-Asberg Depression Rating Scale (MADRS) are among the most widely used outcome measures for clinical trials of medications for Bipolar Disorder (BD). Nonetheless, very few studies have examined the measurement characteristics of the YMRS and MADRS in individuals with BD using modern psychometric methods. The present study evaluated the YMRS and MADRS in the Systematic Treatment Enhancement Program for BD (STEP-BD) study using Item Response Theory (IRT). Baseline data from 3716 STEP-BD participants were available for the present analysis. The Graded Response Model (GRM) was fit separately to YMRS and MADRS item responses. Differential item functioning (DIF) was examined by regressing a variety of clinically relevant covariates (e.g., sex, substance dependence) on all test items and on the latent symptom severity dimension, within each scale. Both scales: 1) contained several items that provided little or no psychometric information, 2) were inefficient, in that the majority of item response categories did not provide incremental psychometric information, 3) poorly measured participants outside of a narrow band of severity, 4) evidenced DIF for nearly all items, suggesting that item responses were, in part, determined by factors other than symptom severity. Limited to outpatients; DIF analysis only sensitive to certain forms of DIF. The present study provides evidence for significant measurement problems involving the YMRS and MADRS. More work is needed to refine these measures and/or develop suitable alternative measures of BD symptomatology for clinical trials research. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. Théorie de Perron-Frobenius non linéaire et méthodes numériques max-plus pour la résolution d'équations d'Hamilton-Jacobi

    OpenAIRE

    Qu , Zheng

    2013-01-01

    Dynamic programming is one of the main approaches to solve optimal control problems. It reduces the latter problems to Hamilton-Jacobi partial differential equations (PDE). Several techniques have been proposed in the literature to solve these PDE. We mention, for example, finite difference schemes, the so-called discrete dynamic programming method or semi-Lagrangian method, or the antidiffusive schemes. All these methods are grid-based, i.e., they require a discretization of the state space,...

  6. Prehistoric horticultural adaptation of soils in the middle Waikato Basin : review and evidence from S14/201 and S14/185, Hamilton

    International Nuclear Information System (INIS)

    Gumbley, W.; Higham, T.F.G.; Low, D.J.

    2004-01-01

    The middle Waikato Basin contains extensive evidence, reviewed here, for the modification of soils for horticulture (gardening) by pre-European Maori. We investigated an area of Maori gardens at archaeological sites S14/201 and S14/185 in Hamilton City. Two groups of multiple, near-circular hollows, each about 0.3 m in diameter and infilled with gravelly sand, were exposed during the site excavations. The hollows, extending through modified A horizon materials into upper B horizon materials, are interpreted as representing the lower part of small truncated mounds (puke) that had been built up by early Maori for growing kumara (Ipomoea batatas). The hollows were grouped in a distinctive quincunx-like pattern in which four hollows formed the corners of a square with one hollow in the centre. The characteristics and layout of the hollows match historical descriptions of mounds used by Maori gardeners. We also used particle-sized analysis to quantify the extent to which upper horizons of the antedecent soils had been modified by the addition of gravel and sand excavated from borrow pits in adjacent volcanogenic alluvium (Hinuera Formation). A radiocarbon date obtained from charcoal found in a fireplace under the modified A horizon and near the hollows suggests that the site was occupied in the late fifteenth century. Identification to species level of charcoal fragments found in the modified soil suggests that site S14/201 may have been cleared of large podocarp trees not long before gardening activities began. This conclusion is supported by similar evidence from another site on the same stretch of the Waikato River. If so, such late (localised) deforestation contrasts with evidence from other palaeoenvironmental studies that shows regional deforestation began considerably earlier (about AD 1300) in the Waikato region. (author). 63 refs., 9 figs., 7 tabs

  7. Results of the radiological verification survey at the former Herring-Hall-Marvin Safe Company, 1550 Grand Boulevard, Hamilton Ohio (HO001V)

    International Nuclear Information System (INIS)

    Murray, M.E.; allred, J.F.; Johnson, C.A.

    1995-11-01

    During the period between the 1940s and early 1950s, the Herring-Hall-Marvin Safe Company, 1550 Grand Boulevard, Hamilton, Ohio, was one company under subcontract to the Manhattan Engineer District (MED), and the Atomic Energy Commission (AEC), the lead agencies in the development of nuclear energy for defense-related projects. The US Department of Energy (DOE) conducted radiological surveys of these sites to evaluate current radiological conditions as part of the Formerly Utilized Sites Remedial Action Program (FUSRAP). In 1988, a radiological survey of the Herring-Hall-Marvin Safe Company facility was conducted, and after small fragments of uranium metal were removed, no beta or gamma radiation above background was detected and the building was dismissed from any additional DOE restrictions. In 1993, it was discovered that a portion of the actual machining work was conducted on the third floor of the facility, located in the southeastern comer of the building. At the request of DOE, this part of the facility was radiologically surveyed by an ORNL survey team to determine whether fixed surface contamination could be found that might exceed the DOE guidelines. Results of this radiological survey indicated 238 U contamination in excess of the DOE criteria for surface contamination, and the site was recommended for remediation. In February and March of 1995, a verification survey of the third floor of the former Herring-Hall-Marvin Safe Company facility by an ORNL survey team was performed in conjunction with decontamination operations conducted under the supervision of Bechtel National Incorporated. The verification survey included gamma scans at the surface and at one meter, alpha and beta-gamma scans for fixed contamination, and smears for transferable contamination

  8. Feynman formulae and phase space Feynman path integrals for tau-quantization of some Lévy-Khintchine type Hamilton functions

    Energy Technology Data Exchange (ETDEWEB)

    Butko, Yana A., E-mail: yanabutko@yandex.ru, E-mail: kinderknecht@math.uni-sb.de [Bauman Moscow State Technical University, 2nd Baumanskaya street, 5, Moscow 105005, Russia and University of Saarland, Postfach 151150, D-66041 Saarbrücken (Germany); Grothaus, Martin, E-mail: grothaus@mathematik.uni-kl.de [University of Kaiserslautern, 67653 Kaiserslautern (Germany); Smolyanov, Oleg G., E-mail: Smolyanov@yandex.ru [Lomonosov Moscow State University, Vorob’evy gory 1, Moscow 119992 (Russian Federation)

    2016-02-15

    Evolution semigroups generated by pseudo-differential operators are considered. These operators are obtained by different (parameterized by a number τ) procedures of quantization from a certain class of functions (or symbols) defined on the phase space. This class contains Hamilton functions of particles with variable mass in magnetic and potential fields and more general symbols given by the Lévy-Khintchine formula. The considered semigroups are represented as limits of n-fold iterated integrals when n tends to infinity. Such representations are called Feynman formulae. Some of these representations are constructed with the help of another pseudo-differential operator, obtained by the same procedure of quantization; such representations are called Hamiltonian Feynman formulae. Some representations are based on integral operators with elementary kernels; these are called Lagrangian Feynman formulae. Langrangian Feynman formulae provide approximations of evolution semigroups, suitable for direct computations and numerical modeling of the corresponding dynamics. Hamiltonian Feynman formulae allow to represent the considered semigroups by means of Feynman path integrals. In the article, a family of phase space Feynman pseudomeasures corresponding to different procedures of quantization is introduced. The considered evolution semigroups are represented as phase space Feynman path integrals with respect to these Feynman pseudomeasures, i.e., different quantizations correspond to Feynman path integrals with the same integrand but with respect to different pseudomeasures. This answers Berezin’s problem of distinguishing a procedure of quantization on the language of Feynman path integrals. Moreover, the obtained Lagrangian Feynman formulae allow also to calculate these phase space Feynman path integrals and to connect them with some functional integrals with respect to probability measures.

  9. The Major Depressive Disorder Hierarchy: Rasch Analysis of 6 items of the Hamilton Depression Scale Covering the Continuum of Depressive Syndrome.

    Directory of Open Access Journals (Sweden)

    Lucas Primo de Carvalho Alves

    Full Text Available Melancholic features of depression (MFD seem to be a unidimensional group of signs and symptoms. However, little importance has been given to the evaluation of what features are related to a more severe disorder. That is, what are the MFD that appear only in the most depressed patients. We aim to demonstrate how each MFD is related to the severity of the major depressive disorder.We evaluated both the Hamilton depression rating scale (HDRS-17 and its 6-item melancholic subscale (HAM-D6 in 291 depressed inpatients using Rasch analysis, which computes the severity of each MFD. Overall measures of model fit were mean (±SD of items and persons residual = 0 (±1; low χ2 value; p>0.01.For the HDRS-17 model fit, mean (±SD of item residuals = 0.35 (±1.4; mean (±SD of person residuals = -0.15 (±1.09; χ2 = 309.74; p<0.00001. For the HAM-D6 model fit, mean (±SD of item residuals = 0.5 (±0.86; mean (±SD of person residuals = 0.15 (±0.91; χ2 = 56.13; p = 0.196. MFD ordered by crescent severity were depressed mood, work and activities, somatic symptoms, psychic anxiety, guilt feelings, and psychomotor retardation.Depressed mood is less severe, while guilt feelings and psychomotor retardation are more severe MFD in a psychiatric hospitalization. Understanding depression as a continuum of symptoms can improve the understanding of the disorder and may improve its perspective of treatment.

  10. Feynman formulae and phase space Feynman path integrals for tau-quantization of some Lévy-Khintchine type Hamilton functions

    International Nuclear Information System (INIS)

    Butko, Yana A.; Grothaus, Martin; Smolyanov, Oleg G.

    2016-01-01

    Evolution semigroups generated by pseudo-differential operators are considered. These operators are obtained by different (parameterized by a number τ) procedures of quantization from a certain class of functions (or symbols) defined on the phase space. This class contains Hamilton functions of particles with variable mass in magnetic and potential fields and more general symbols given by the Lévy-Khintchine formula. The considered semigroups are represented as limits of n-fold iterated integrals when n tends to infinity. Such representations are called Feynman formulae. Some of these representations are constructed with the help of another pseudo-differential operator, obtained by the same procedure of quantization; such representations are called Hamiltonian Feynman formulae. Some representations are based on integral operators with elementary kernels; these are called Lagrangian Feynman formulae. Langrangian Feynman formulae provide approximations of evolution semigroups, suitable for direct computations and numerical modeling of the corresponding dynamics. Hamiltonian Feynman formulae allow to represent the considered semigroups by means of Feynman path integrals. In the article, a family of phase space Feynman pseudomeasures corresponding to different procedures of quantization is introduced. The considered evolution semigroups are represented as phase space Feynman path integrals with respect to these Feynman pseudomeasures, i.e., different quantizations correspond to Feynman path integrals with the same integrand but with respect to different pseudomeasures. This answers Berezin’s problem of distinguishing a procedure of quantization on the language of Feynman path integrals. Moreover, the obtained Lagrangian Feynman formulae allow also to calculate these phase space Feynman path integrals and to connect them with some functional integrals with respect to probability measures

  11. Comparison between frailty index of deficit accumulation and phenotypic model to predict risk of falls: data from the global longitudinal study of osteoporosis in women (GLOW Hamilton cohort.

    Directory of Open Access Journals (Sweden)

    Guowei Li

    Full Text Available To compare the predictive accuracy of the frailty index (FI of deficit accumulation and the phenotypic frailty (PF model in predicting risks of future falls, fractures and death in women aged ≥55 years.Based on the data from the Global Longitudinal Study of Osteoporosis in Women (GLOW 3-year Hamilton cohort (n = 3,985, we compared the predictive accuracy of the FI and PF in risks of falls, fractures and death using three strategies: (1 investigated the relationship with adverse health outcomes by increasing per one-fifth (i.e., 20% of the FI and PF; (2 trichotomized the FI based on the overlap in the density distribution of the FI by the three groups (robust, pre-frail and frail which were defined by the PF; (3 categorized the women according to a predicted probability function of falls during the third year of follow-up predicted by the FI. Logistic regression models were used for falls and death, while survival analyses were conducted for fractures.The FI and PF agreed with each other at a good level of consensus (correlation coefficients ≥ 0.56 in all the three strategies. Both the FI and PF approaches predicted adverse health outcomes significantly. The FI quantified the risks of future falls, fractures and death more precisely than the PF. Both the FI and PF discriminated risks of adverse outcomes in multivariable models with acceptable and comparable area under the curve (AUCs for falls (AUCs ≥ 0.68 and death (AUCs ≥ 0.79, and c-indices for fractures (c-indices ≥ 0.69 respectively.The FI is comparable with the PF in predicting risks of adverse health outcomes. These findings may indicate the flexibility in the choice of frailty model for the elderly in the population-based settings.

  12. Comparison between frailty index of deficit accumulation and phenotypic model to predict risk of falls: data from the global longitudinal study of osteoporosis in women (GLOW) Hamilton cohort.

    Science.gov (United States)

    Li, Guowei; Thabane, Lehana; Ioannidis, George; Kennedy, Courtney; Papaioannou, Alexandra; Adachi, Jonathan D

    2015-01-01

    To compare the predictive accuracy of the frailty index (FI) of deficit accumulation and the phenotypic frailty (PF) model in predicting risks of future falls, fractures and death in women aged ≥55 years. Based on the data from the Global Longitudinal Study of Osteoporosis in Women (GLOW) 3-year Hamilton cohort (n = 3,985), we compared the predictive accuracy of the FI and PF in risks of falls, fractures and death using three strategies: (1) investigated the relationship with adverse health outcomes by increasing per one-fifth (i.e., 20%) of the FI and PF; (2) trichotomized the FI based on the overlap in the density distribution of the FI by the three groups (robust, pre-frail and frail) which were defined by the PF; (3) categorized the women according to a predicted probability function of falls during the third year of follow-up predicted by the FI. Logistic regression models were used for falls and death, while survival analyses were conducted for fractures. The FI and PF agreed with each other at a good level of consensus (correlation coefficients ≥ 0.56) in all the three strategies. Both the FI and PF approaches predicted adverse health outcomes significantly. The FI quantified the risks of future falls, fractures and death more precisely than the PF. Both the FI and PF discriminated risks of adverse outcomes in multivariable models with acceptable and comparable area under the curve (AUCs) for falls (AUCs ≥ 0.68) and death (AUCs ≥ 0.79), and c-indices for fractures (c-indices ≥ 0.69) respectively. The FI is comparable with the PF in predicting risks of adverse health outcomes. These findings may indicate the flexibility in the choice of frailty model for the elderly in the population-based settings.

  13. Frailty Change and Major Osteoporotic Fracture in the Elderly: Data from the Global Longitudinal Study of Osteoporosis in Women 3-Year Hamilton Cohort.

    Science.gov (United States)

    Li, Guowei; Papaioannou, Alexandra; Thabane, Lehana; Cheng, Ji; Adachi, Jonathan D

    2016-04-01

    Investigating the cumulative rate of deficits and the change of a frailty index (FI) chronologically is helpful in clinical and research settings in the elderly. However, limited evidence for the change of frailty before and after some nonfatal adverse health event such as a major osteoporotic fracture (MOF) is available. Data from the Global Longitudinal Study of Osteoporosis in Women 3-Year Hamilton cohort were used in this study. The changes of FI before and after onset of MOF were compared between the women with and without incident MOF. We also evaluated the relationship between risk of MOF, falls, and death and the change of FI and the absolute FI measures. There were 3985 women included in this study (mean age 69.4 years). The change of FI was significantly larger in the women with MOF than those without MOF at year 1 (0.085 versus 0.067, p = 0.036) and year 2 (0.080 versus 0.052, p = 0.042) post-baseline. The FI change was not significantly related with risk of MOF independently of age. However, the absolute FI measures were significantly associated with increased risk of MOF, falls, and death independently of age. In summary, the increase of the FI is significantly larger in the elderly women experiencing a MOF than their peer controls, indicating their worsening frailty and greater deficit accumulation after a MOF. Measures of the FI change may aid in the understanding of cumulative aging nature in the elderly and serve as an instrument for intervention planning and assessment. © 2015 American Society for Bone and Mineral Research.

  14. SURVEY, HAMILTON COUNTY, FL, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Survey data includes spatial datasets and data tables necessary to digitally represent data collected in the survey phase of the study. (Source: FEMA Guidelines and...

  15. BASEMAP, HAMILTON COUNTY, FL, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — FEMA Framework Basemap datasets comprise six of the seven FGDC themes of geospatial data that are used by most GIS applications (Note: the seventh framework theme,...

  16. HYDROLOGY, HAMILTON COUNTY, FL, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Hydrology data include spatial datasets and data tables necessary for documenting the hydrologic procedures for estimating flood discharges for a flood insurance...

  17. FLOODPLAIN, HAMILTON COUNTY, OHIO, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Floodplain Mapping/Redelineation study deliverables depict and quantify the flood risks for the study area. The primary risk classifications used are the...

  18. Effects of changes in pumping on regional groundwater-flow paths, 2005 and 2010, and areas contributing recharge to discharging wells, 1990–2010, in the vicinity of North Penn Area 7 Superfund site, Montgomery County, Pennsylvania

    Science.gov (United States)

    Senior, Lisa A.; Goode, Daniel J.

    2017-06-06

    A previously developed regional groundwater flow model was used to simulate the effects of changes in pumping rates on groundwater-flow paths and extent of recharge discharging to wells for a contaminated fractured bedrock aquifer in southeastern Pennsylvania. Groundwater in the vicinity of the North Penn Area 7 Superfund site, Montgomery County, Pennsylvania, was found to be contaminated with organic compounds, such as trichloroethylene (TCE), in 1979. At the time contamination was discovered, groundwater from the underlying fractured bedrock (shale) aquifer was the main source of supply for public drinking water and industrial use. As part of technical support to the U.S. Environmental Protection Agency (EPA) during the Remedial Investigation of the North Penn Area 7 Superfund site from 2000 to 2005, the U.S. Geological Survey (USGS) developed a model of regional groundwater flow to describe changes in groundwater flow and contaminant directions as a result of changes in pumping. Subsequently, large decreases in TCE concentrations (as much as 400 micrograms per liter) were measured in groundwater samples collected by the EPA from selected wells in 2010 compared to 2005‒06 concentrations.To provide insight on the fate of potentially contaminated groundwater during the period of generally decreasing pumping rates from 1990 to 2010, steady-state simulations were run using the previously developed groundwater-flow model for two conditions prior to extensive remediation, 1990 and 2000, two conditions subsequent to some remediation 2005 and 2010, and a No Pumping case, representing pre-development or cessation of pumping conditions. The model was used to (1) quantify the amount of recharge, including potentially contaminated recharge from sources near the land surface, that discharged to wells or streams and (2) delineate the areas contributing recharge that discharged to wells or streams for the five conditions.In all simulations, groundwater divides differed from

  19. Population structure and genetic diversity of Indian Major Carp, Labeo rohita (Hamilton, 1822) from three phylo-geographically isolated riverine ecosystems of India as revealed by mtDNA cytochrome b region sequences.

    Science.gov (United States)

    Behera, Bijay Kumar; Baisvar, Vishwamitra Singh; Kunal, Swaraj Priyaranjan; Meena, Dharmendra Kumar; Panda, Debarata; Pakrashi, Sudip; Paria, Prasenjit; Das, Pronob; Bhakta, Dibakar; Debnath, Dipesh; Roy, Suvra; Suresh, V R; Jena, J K

    2018-03-01

    The population structure and genetic diversity of Rohu (Labeo rohita Hamilton, 1822) was studied by analysis of the partial sequences of mitochondrial DNA cytochrome b region. We examined 133 samples collected from six locations in three geographically isolated rivers of India. Analysis of 11 haplotypes showed low haplotype diversity (0.00150), nucleotide diversity (π) (0.02884) and low heterogeneity value (0.00374). Analysis of molecular variance (AMOVA) revealed the genetic diversity of L. rohita within population is very high than between the populations. The Fst scores (-0.07479 to 0.07022) were the indication of low genetic structure of L. rohita populations of three rivers of India. Conspicuously, Farakka-Bharuch population pair Fst score of 0.0000, although the sampling sites are from different rivers. The phylogenetic reconstruction of unique haplotypes revealed sharing of a single central haplotype (Hap_1) by all the six populations with a point mutations ranging from 1-25 nucleotides.

  20. Análisis de sensibilidad en la estimación de la función característica de punta de hamilton de la sísmica geométrica

    Directory of Open Access Journals (Sweden)

    Montes Vides Luis Alfredo

    2000-08-01

    Full Text Available Usando la aproximación de segundo orden de los tiempos de Tránsito en modelos sísmicos constituidos por capas homogéneas e isotrópicas separadas por interfaces suaves, los tiempos de los eventos de reflexión registrados en vecindad del rayo central pueden estimarse a partir de una función hiperbólica que corresponde a la función característica de punto de Hamilton, la cual no es conocida numéricamente en la óptica geométrica. En la sísmica, esta se puede determinar a través de una regresión lineal entre las coordenadas fuente-detector y los tiempos de Tránsito de por lo menos nueve rayos apropiadamente seleccionados y registrados en configuraciones de cubrimiento multiple. Un análisis de sensibilidad permite conocer la estabilidad y robustez del método de  regresión que estima la función caractéristica de los tiempos de Tránsito.

    Using the second-order approximations of the traveltimes in a seismic model which consists of a pile of homogeneous layers separated by smooth interfaces, the traveltimes of reflection events registered in the vicinity of the central ray can be estimated from an hyperbolic function that corresponds to Hamilton's point characteristic in optics, where it is not numerically known. In seismic, it can be determined through a linear regression between the source-detector coordinates and the traveltimes of at least nine rays properly selected and registered in multiple fold configurations. A sensibility analysis allows to know the stability and robustness of the linear regression method to estimate the

  1. The validity of dysthymia to predict clinical depressive symptoms as measured by the Hamilton Depression Scale at the 5-year follow-up of patients with first episode depression

    DEFF Research Database (Denmark)

    Bech, Per; Kessing, Lars Vedel; Bukh, Jens Drachmann

    2016-01-01

    BACKGROUND: In long-term follow-up studies on depression, the Eysenck Neuroticism Scale (ENS) at the score level of dysthymia has been found to be valid at predicting poor outcome. AIMS: The ENS dysthymia level was compared with the Beck Depression Inventory (BDI) level to predict the prevalence...... of depressive symptoms at the 5-year follow-up of patients initially diagnosed with first episode depression using the Hamilton Depression Scale (HAM-D) to express depressive symptoms. METHODS: A total of 301 in- or outpatients aged 18-70 years with a recent single depressive episode were assessed by ENS, BDI......, and HAM-D from 2005-2007. At 5-year follow-up from 2011-2013, the participants were re-assessed by HAM-D. The HAM-D was used to measure depressive symptoms at the 5-year follow-up. The Mokken analysis was used to indicate scalability of the BDI and ENS. RESULTS: A total of 185 participants were available...

  2. Improvement of depressive symptoms in patients with moderate-to-severe psoriasis treated with ustekinumab: an open label trial validated using beck depression inventory, Hamilton depression rating scale measures and 18fluorodeoxyglucose (FDG) positron emission tomography (PET).

    Science.gov (United States)

    Kim, Seong-Jang; Park, Min-Young; Pak, Kyoungjune; Han, Junhee; Kim, Gun-Wook; Kim, Hoon-Soo; Ko, Hyun-Chang; Kim, Moon-Bum; Kim, Byung-Soo

    2018-05-07

    Psoriasis is a chronic skin disease associated with psychiatric co-morbidities, especially depression. Early detection of psychological vulnerability in patients with psoriasis seems to be of great clinical importance and significantly impacts the quality of life of the patients. We sought to clarify the association between psoriasis and depressive symptoms in patients with moderate-to-severe psoriasis, and to determine the risk factors for depressive symptoms and analyze the effect of ustekinumab on the symptoms. We also aimed to evaluate the changes in glucose metabolism using 18 fluorodeoxyglucose (FDG) positron emission tomography (FDG-PET). Fifteen patients with moderate-to-severe psoriasis scheduled to be treated with ustekinumab were enrolled. At baseline and after achieving a 75% reduction in the Psoriasis Area and Severity Index (PASI) score (PASI75), all patients underwent a psychiatric interview and FDG-PET. Fifteen healthy volunteers were enrolled for comparison. Patients with moderate-to-severe psoriasis were more depressed than those in the control group were (p Inventory and Hamilton Depression Rating Scale psychiatric interviews (p < .05). However, FDG-PET of the brain showed no significant difference before and after PASI75 achievement using ustekinumab injection. Patients with moderate-to-severe psoriasis are at an increased risk for depressive symptoms, and treatment with ustekinumab may be beneficial. FDG-PET does not reflect the changes in depressive symptoms in such patients.

  3. Validation of the 17-item Hamilton Depression Rating Scale definition of response for adults with major depressive disorder using equipercentile linking to Clinical Global Impression scale ratings: analysis of Pharmacogenomic Research Network Antidepressant Medication Pharmacogenomic Study (PGRN-AMPS) data.

    Science.gov (United States)

    Bobo, William V; Angleró, Gabriela C; Jenkins, Gregory; Hall-Flavin, Daniel K; Weinshilboum, Richard; Biernacka, Joanna M

    2016-05-01

    The study aimed to define thresholds of clinically significant change in 17-item Hamilton Depression Rating Scale (HDRS-17) scores using the Clinical Global Impression-Improvement (CGI-I) Scale as a gold standard. We conducted a secondary analysis of individual patient data from the Pharmacogenomic Research Network Antidepressant Medication Pharmacogenomic Study, an 8-week, single-arm clinical trial of citalopram or escitalopram treatment of adults with major depression. We used equipercentile linking to identify levels of absolute and percent change in HDRS-17 scores that equated with scores on the CGI-I at 4 and 8 weeks. Additional analyses equated changes in the HDRS-7 and Bech-6 scale scores with CGI-I scores. A CGI-I score of 2 (much improved) corresponded to an absolute decrease (improvement) in HDRS-17 total score of 11 points and a percent decrease of 50-57%, from baseline values. Similar results were observed for percent change in HDRS-7 and Bech-6 scores. Larger absolute (but not percent) decreases in HDRS-17 scores equated with CGI-I scores of 2 in persons with higher baseline depression severity. Our results support the consensus definition of response based on HDRS-17 scores (>50% decrease from baseline). A similar definition of response may apply to the HDRS-7 and Bech-6. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  4. Cálculo dos níveis de energia do átomo de hidrogênio sob a ação de um campo magnético externo utilizando a equação de Hamilton-Jacobi relativística

    OpenAIRE

    Silva, Gesiel Gomes

    2014-01-01

    Nosso trabalho consistiu em encontrar os níveis de energia do átomo de hidrogênio sob a ação de um campo magnético externo constante. Utilizamos o formalismo de Hamilton-Jacobi relativístico para introduzir o campo magnético e para obter uma equação para o átomo de hidrogênio sob a ação de um campo magnético uniforme. Propusemos também uma função, com base em uma expansão polinomial, como solução da equação obtida a partir do formalismo de Hamilton-Jacobi possibilitando assim a solução numér...

  5. Sensitivity to changes during antidepressant treatment: a comparison of unidimensional subscales of the Inventory of Depressive Symptomatology (IDS-C) and the Hamilton Depression Rating Scale (HAMD) in patients with mild major, minor or subsyndromal depression.

    Science.gov (United States)

    Helmreich, Isabella; Wagner, Stefanie; Mergl, Roland; Allgaier, Antje-Kathrin; Hautzinger, Martin; Henkel, Verena; Hegerl, Ulrich; Tadić, André

    2012-06-01

    In the efficacy evaluation of antidepressant treatments, the total score of the Hamilton Depression Rating Scale (HAMD) is still regarded as the 'gold standard'. We previously had shown that the Inventory of Depressive Symptomatology (IDS) was more sensitive to detect depressive symptom changes than the HAMD17 (Helmreich et al. 2011). Furthermore, studies suggest that the unidimensional subscales of the HAMD, which capture the core depressive symptoms, outperform the full HAMD regarding the detection of antidepressant treatment effects. The aim of the present study was to compare several unidimensional subscales of the HAMD and the IDS regarding their sensitivity to changes in depression symptoms in a sample of patients with mild major, minor or subsyndromal depression (MIND). Biweekly IDS-C28 and HAMD17 data from 287 patients of a 10-week randomised, placebo-controlled trial comparing the effectiveness of sertraline and cognitive-behavioural group therapy in patients with MIND were converted to subscale scores and analysed during the antidepressant treatment course. We investigated sensitivity to depressive change for all scales from assessment-to-assessment, in relation to depression severity level and placebo-verum differences. The subscales performed similarly during the treatment course, with slight advantages for some subscales in detecting treatment effects depending on the treatment modality and on the items included. Most changes in depressive symptomatology were detected by the IDS short scale, but regarding the effect sizes, it performed worse than most subscales. Unidimensional subscales are a time- and cost-saving option in judging drug therapy outcomes, especially in antidepressant treatment efficacy studies. However, subscales do not cover all facets of depression (e.g. atypical symptoms, sleep disturbances), which might be important for comprehensively understanding the nature of the disease depression. Therefore, the cost-to-benefit ratio must be

  6. The validity of dysthymia to predict clinical depressive symptoms as measured by the Hamilton Depression Scale at the 5-year follow-up of patients with first episode depression.

    Science.gov (United States)

    Bech, Per; Kessing, Lars Vedel; Bukh, Jens Drachmann

    2016-11-01

    In long-term follow-up studies on depression, the Eysenck Neuroticism Scale (ENS) at the score level of dysthymia has been found to be valid at predicting poor outcome. The ENS dysthymia level was compared with the Beck Depression Inventory (BDI) level to predict the prevalence of depressive symptoms at the 5-year follow-up of patients initially diagnosed with first episode depression using the Hamilton Depression Scale (HAM-D) to express depressive symptoms. A total of 301 in- or outpatients aged 18-70 years with a recent single depressive episode were assessed by ENS, BDI, and HAM-D from 2005-2007. At 5-year follow-up from 2011-2013, the participants were re-assessed by HAM-D. The HAM-D was used to measure depressive symptoms at the 5-year follow-up. The Mokken analysis was used to indicate scalability of the BDI and ENS. A total of 185 participants were available for the psychometric analysis of the ESN and BDI, and the scalability was found acceptable. In total, 99 patients were available for the predictive analysis. Both the ENS and the BDI were significantly associated with depressive symptoms (HAM-D17 ≥ 8) at the 5-year follow-up (p Dysthymia as measured by the two self-rating scales ENS and BDI can be considered part of a 'double depression' in patients with first episode depression, implying an existence of depressive symptoms at the 5-year follow-up. Evaluation of dysthymia or neuroticism is important to perform, even in patients with first episode depression, in order to identify 'double depression'.

  7. Algebra and Geometry of Hamilton's Quaternions

    Indian Academy of Sciences (India)

    IAS Admin

    utility upon seeing the remarkable Ferro–Tartaglia–Car- dano–Bombelli formula for a ..... which goes back to Diophantus and Brahmagupta. The analogous ..... used by programmers to animate camera movements [12] in video games (such as ...

  8. DCS Hydraulic Submission for Hamilton County, Ohio

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Recent developments in digital terrain and geospatial database management technology make it possible to protect this investment for existing and future projects to...

  9. Hamilton principle for the dual electrodynamics

    International Nuclear Information System (INIS)

    Souza Silva, Saulo Carneiro de

    1995-01-01

    The present work discusses the classical electromagnetic theory in the presence of magnetic monopoles. We review the connection between such objects and the long standing problem of charge quantization and the main theoretical difficulties in formulating the classical dual electromagnetic theory in terms of an action principle. We show that a deeper understanding of the source of such difficulties leads naturally to the construction of a variational principle for a non-local Lagrangian from which all the (local) dynamical equations for electric, magnetic charges and fields can be obtained. (author)

  10. Spectral Radius and Hamiltonicity of Graphs

    Czech Academy of Sciences Publication Activity Database

    Fiedler, Miroslav; Nikiforov, V.

    2010-01-01

    Roč. 432, č. 9 (2010), s. 2170-2173 ISSN 0024-3795 Institutional research plan: CEZ:AV0Z10300504 Keywords : Hamiltonian cycle * Hamiltonian path * spectral radius Subject RIV: BA - General Mathematics Impact factor: 1.005, year: 2010

  11. Re-evaluation of the definition of remission on the 17-item Hamilton Depression Rating Scale based on recovery in health-related quality of life in an observational post-marketing study.

    Science.gov (United States)

    Sawamura, Jitsuki; Ishigooka, Jun; Nishimura, Katsuji

    2018-01-16

    Although a score of less than 7 for the 17-item Hamilton Depression Rating Scale (HAM-D17) has been widely adopted to define remission of depression, a full recovery from depression is closely related to the patient's quality of life as well. Accordingly, we re-evaluated this definition of remission using HAM-D17 in comparison with the corresponding score for health-related quality of life (HRQOL) measured by the SF-36. Using the data for depressive patients reported by GlaxoSmithKline K.K. (Study No. BRL29060A/863) in a post-marketing observational study of paroxetine, with a sample size of n = 722, multivariate logistic regression was performed with the HAM-D17 score as a dependent variable and with each of the eight domain scores of HRQOL (from the SF-36) transformed into a binominal form according to the national standard value for Japan. Then, area under curve of receiver operating characteristic analyses were conducted. Based on the obtained results, a multivariate analysis was performed using the HAM-D17 score in a binomial form with HAM-D17 as a dependent variable and with each of the eight HRQOL domain scores (SF-36) as binominalized independent variables. A cutoff value for the HAM-D17 score of 5 provided the maximum ROC-AUC at "0.864." The significantly associated scores of the eight HRQOL domains (SF-36) were identified for the HAM-D17 cutoff values of ≥5 and ≤4. The scores for physical functioning (odds ratio, 0.473), bodily pain (0.557), vitality (0.379), social functioning (0.540), role-emotion (0.265), and mental health (0.467) had a significant negative association with the HAM-D17 score (p < 0.05), and HRQOL domain scores for HAM-D17 ≥ 5 were significantly lower compared with those for HAM-D17 ≤ 4. A cutoff value for HAM-D17 of less than or equal to 4 was the best candidate for indicating remission of depression when the recovery of HRQOL is considered. Restoration of social function and performance should be considered

  12. Análisis del comportamiento de la inflación trimestral en Colombia bajo cambios de régimen: Una evidencia a través del modelo "Switching" de Hamilton.

    Directory of Open Access Journals (Sweden)

    Luis Fernando Melo

    2010-05-01

    Full Text Available Este trabajo tiene como propósito estudiar la evolución de la inflación trimestral en Colombia, durante el período comprendido entre 1954 y 1996, a través de la metodología de Hamilton(1989 y segundo presentar algunos conceptos relacionados con dicha metodología, la cual introduce cambios de régimen en el análisis convencional de series de tiempo. En general, esta metodología permite estimar modelos ARIMA con parámetros o varianzas cambiantes en el tiempo. En este caso, tales cambios en el modelo de la inflación se suponen asociados a posibles regímenes distintos donde la inflación presenta cambios en su nivel o en su variabilidad. Esta modelación posibilita el reconocimiento de los distintos regímenes a través del tiempo (por ejemplo dos regímenes: inflación alta e inflación baja en lo referente a su tiempo promedio de duración y a la probabilidad asociada de cada uno de ellos, es decir, la probabilidad de estar en un régimen particular en un momento dado del tiempo. Las probabilidades de transición estimadas, permiten concluir, por ejemplo, que al estar en un régimen de inflación trimestral moderado, la probabilidad de permanecer en éste es muy alta (0.94, en tanto que pasar de éste a un régimen de inflación promedio alta tiene una probabilidad de (0.05, la cual es cinco veces mayor que la estimada para la transición de moderada a baja (0.01. Adicionalmente, se puede observar que la máxima probabilidad de permanecer en un mismo régimen se tiene en aquel caracterizado como de inflación y variabilidad moderadas.

  13. OrthoImagery Submission for Montgomery County, GA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — NAIP imagery is available for distribution within 60 days of the end of a flying season and is intended to provide current information of agricultural conditions in...

  14. Hamilton principle for the dual electrodynamics; Principio de Hamilton para a eletrodinamica dual

    Energy Technology Data Exchange (ETDEWEB)

    Souza Silva, Saulo Carneiro de

    1995-12-31

    The present work discusses the classical electromagnetic theory in the presence of magnetic monopoles. We review the connection between such objects and the long standing problem of charge quantization and the main theoretical difficulties in formulating the classical dual electromagnetic theory in terms of an action principle. We show that a deeper understanding of the source of such difficulties leads naturally to the construction of a variational principle for a non-local Lagrangian from which all the (local) dynamical equations for electric, magnetic charges and fields can be obtained. (author) 53 refs.

  15. 78 FR 45956 - Notice of Inventory Completion: Hamilton County Department of Parks and Recreation, Hamilton...

    Science.gov (United States)

    2013-07-30

    ... osteological analysis of the human remains as a whole has not been completed. The human remains underwent archaeological processing and analysis under the direction of Indiana University Purdue University at Ft. Wayne... tooth; 1 lot of mussel shell fragments; 1 lot of non-formal uniface; 2 lots of ochre; 1 pestle fragment...

  16. Eutropiichthys vacha (Hamilton, 1822, a threatened fish of Indian subcontinent

    Directory of Open Access Journals (Sweden)

    Sandipan Gupta

    2016-08-01

    Full Text Available Eutropiichthys vacha (Batchwa vacha is a freshwater catfish species having high economic value. It is a very popular table fish among the consumers due to high nutritional value and taste. Just recently small specimens of this species have also made their entry in ornamental fish markets. Recently due to number of reasons, populations of this fish species are facing the threat of extinction. It has already been documented as Endangered in India and Critically Endangered in Bangladesh. The present report has been prepared to summarize the information available on different aspects of this threatened fish species as well as to point out the possible measures that should be considered for its conservation.

  17. Genetic diversity analysis of Labeo gonius (Hamilton, 1822) in three ...

    African Journals Online (AJOL)

    a

    2013-05-08

    May 8, 2013 ... tool to characterize population-level genetic variation in various fish species ... rise to protein variants called allozymes that differ slightly in electric charges. ..... Black Sea Coast. Acta zool. Bulg. ... Inc., Florida, USA. 350 pp.

  18. Hamilton Park Care Facility, Balrothery, Balbriggan, Co. Dublin.

    LENUS (Irish Health Repository)

    Galvin, Miriam

    2018-01-27

    Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a debilitating terminal condition. Informal caregivers are key figures in ALS care provision. The physical, psychological and emotional impact of providing care in the home requires appropriate assistance and support. The objective of this analysis is to explore the needs of informal ALS caregivers across the caregiving course.

  19. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, HAMILTON COUNTY, OHIO, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  20. Value functions for certain class of Hamilton Jacobi equations

    Indian Academy of Sciences (India)

    in Rn × R+ and m > 1, with bounded, Lipschitz continuous initial data. We give a. Hopf-Lax type representation for the value function and also characterize the set of minimizing paths. It is shown that the minimizing paths in the representation of value function need not be straight lines. Then we consider HJE with ...

  1. A bioenergetic model for zebrafish Danio rerio (Hamilton)

    Science.gov (United States)

    Chizinski, C.J.; Sharma, Bibek; Pope, K.L.; Patino, R.

    2008-01-01

    A bioenergetics model was developed from observed consumption, respiration and growth rates for zebrafish Danio rerio across a range (18-32?? C) of water temperatures, and evaluated with a 50 day laboratory trial at 28?? C. No significant bias in variable estimates was found during the validation trial; namely, predicted zebrafish mass generally agreed with observed mass. ?? 2008 The Authors.

  2. 78 FR 43838 - Airworthiness Directives; Hamilton Sundstrand Corporation Propellers

    Science.gov (United States)

    2013-07-22

    ... predicts a significantly lower fleet risk than the prior qualitative analysis. Accordingly, we withdraw the... qualitative risk assessment. The data gathered was then used for a more representative quantitative risk... qualitative analysis. Withdrawal of the NPRM (78 FR 9001, February 7, 2013) constitutes only such [[Page 43839...

  3. DIGITAL FLOOD INSURANCE RATE MAP DATABASE, HAMILTON COUNTY, FLORIDA, USA

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  4. A Converse to the Cayley-Hamilton Theorem

    Indian Academy of Sciences (India)

    follows that qj = api, where a is a unit. Thus, we must have that the expansion of I into irreducibles is unique. Hence, K[x] is a UFD. A famous theorem of Gauss implies that K[XI' X2,. ,xn] is also an UFD. Gauss's Theorem: R[x] is a UFD, if and only if R is a UFD. For a proof of Gauss's theorem and a detailed proof of the fact that ...

  5. Eutropiichthys vacha (Hamilton, 1822), a threatened fish of Indian subcontinent

    OpenAIRE

    Sandipan Gupta; Samir Banerjee

    2016-01-01

    Eutropiichthys vacha (Batchwa vacha) is a freshwater catfish species having high economic value. It is a very popular table fish among the consumers due to high nutritional value and taste. Just recently small specimens of this species have also made their entry in ornamental fish markets. Recently due to number of reasons, populations of this fish species are facing the threat of extinction. It has already been documented as Endangered in India and Critically Endangered in Bangladesh. The pr...

  6. Effect of zinc, copper and mercury on Channa marulius (Hamilton)

    Energy Technology Data Exchange (ETDEWEB)

    Khangarot, B.S.

    1981-01-01

    Static bioassay acute toxicity tests of zinc, copper and mercury were conducted to determine the median lethal concentrations (LC/sub 50/S) of a freshwater telcost Channa marulius (HAM.) The 96 h LC/sub 50/ for Zn/sup 2 +/ were 25.61 mg/l; 0.90 mg/l for Cu/sup 2 +/ and 0.314 mg/l for Hg/sup 2 +/. However, these values decreased at 240 h of exposure and were: 21.09 mg Zn/sup 2 +//l; 0.66 mg Cu/sup 2 +//l; and 0.31 mg Hg/sup 2 +//l. The relative potency ratio of Zn/Hg, Zn/Cu and Cu/Hg suggests that fish were most sensitive to Hg, followed by Cu and Zn ions. The acute toxicities of mixtures of Zn/sup 2 +/-Cu/sup 2 +/; Zn/sup 2 +/-Hg/sup 2 +/; Cu/sup 2 +/-Hg/sup 2 +/ and Zu/sup 2 +/-Cu/sup 2 +/-Hg/sup 2 +/ up to 48 h of exposure were also investigated. The additive index and ranges for Zn/sup 2 +/-Cu/sup 2 +/ were -0.241 for Zn-Hg; 0.285 for Cu-Hg; and -0.542 for Zn-Cu-Hg. All the mixtures tested showed a greater than additive toxicity because index ranges overlapped zero.

  7. Hamilton Park Care Facility, Balrothery, Balbriggan, Co. Dublin.

    LENUS (Irish Health Repository)

    Ingrand, Isabelle

    2012-04-30

    AbstractBackgroundSeveral studies have shown the influence of the perceptions of aging on the cognitive functioning and the mental and physical health of older people. These relationships have not to date been studied in France where validated instruments are lacking. The primary objective of this study was to validate a French-language version of the Aging Perceptions Questionnaire (APQ) in the French general population aged 65 and over. The secondary objective was to study the stability of the dimensions of this instrument among participants aged 55 to 64.MethodsThe study was proposed to the cohort of the Observatoire Régional du Vieillissement (OPREVI) (observatory of aging), located in a small town in Poitou-Charentes (western France). An anonymous questionnaire including the APQ was sent by mail to inhabitants aged 55 and over. The original English language APQ was described with adults aged 65 and older. It has 32 items distributed on 7 dimensions: timeline chronic and cyclical, positive and negative consequences, positive and negative control and emotional representations.Results656 adults participated in this survey (286 men, 370 women). Among those aged 65 and over (n = 394), the seven-factor structure estimated by confirmatory factor analysis was coherent with original findings. Internal consistency as evaluated by Cronbach alpha, was between 0.83 for consequences negative and 0.52 for control negative. Several dimensions were strongly correlated. Among participants aged 55 to 64 (n = 262), the same factorial model yielded an acceptable fit. Multi-group confirmatory factor analysis concluded to approximate factorial invariance between the two age groups with a null delta in comparative fit index.ConclusionThis study among French people aged 65 and over, added further evidence of the multidimensional structure of the French version of the APQ which is superimposed to the dimensions of the original Irish version. The same factorial structure applies acceptably to the younger group (aged 55–64). The OPREVI study is ongoing, and will collect data on the physical, material and social characteristics of participants. It will therefore be possible to analyse the variables associated with the perceptions of aging. On the basis of an individual\\'s perceptions of aging as captured by this questionnaire, and his or her clinical profile, tailored multi-dimensional assistance could be made available aiming to provide incentives to anticipate or to adapt to difficulties.

  8. TSP tour domination and Hamilton cycle decompositions of regular digraphs

    DEFF Research Database (Denmark)

    Gutin, Gregory; Yeo, Anders

    2001-01-01

    by the relative performance compared to the optimal value. In particular, we show that for the asymmetric traveling salesman problem, there is a deterministic polynomial time algorithm that finds a tour that is at least as good as the median of all tour values. Our algorithm uses an unpublished theorem...

  9. Hamilton's equations for a fluid membrane: axial symmetry

    International Nuclear Information System (INIS)

    Capovilla, R; Guven, J; Rojas, E

    2005-01-01

    Consider a homogeneous fluid membrane, or vesicle, described by the Helfrich-Canham energy, quadratic in the mean curvature. When the membrane is axially symmetric, this energy can be viewed as an 'action' describing the motion of a particle; the contours of equilibrium geometries are identified with particle trajectories. A novel Hamiltonian formulation of the problem is presented which exhibits the following two features: (i) the second derivatives appearing in the action through the mean curvature are accommodated in a natural phase space and (ii) the intrinsic freedom associated with the choice of evolution parameter along the contour is preserved. As a result, the phase space involves momenta conjugate not only to the particle position but also to its velocity, and there are constraints on the phase space variables. This formulation provides the groundwork for a field theoretical generalization to arbitrary configurations, with the particle replaced by a loop in space

  10. Final Environmental Assessment for Temporary Aircraft Relocation to Maxwell Air Force Base 187th Fighter Wing Montgomery Regional Airport Montgomery, Alabama

    Science.gov (United States)

    2012-06-01

    interior construction at Maxwell AFB, such as employment and materials purchasing, will provide minor short-term economic benefits to the local economy...distribution of children and locations where the number of children in the affected area may be disproportionately high (e.g., schools, childcare centers...with its unique Congressional mandate: OSHA regulations categorize substances in terms of their impacts on employee and workplace health and safety

  11. 75 FR 82463 - Yuri I. Montgomery, Respondent; Final Decision and Order

    Science.gov (United States)

    2010-12-30

    ..., U.S. Department of Commerce, Room HCHB 3839, 14th Street and Constitution Ave., NW., Washington, DC... Commerce, Room H-3839, 14th Street & Constitution Avenue, NW., Washington, DC 20230. On behalf of... prohibited items to Macedonia and Slovenia without applying for and obtaining the required export licenses in...

  12. DCS Hydraulics Submission for Montgomery County GA MapMod08

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — Recent developments in digital terrain and geospatial database management technology make it possible to protect this investment for existing and future projects to...

  13. Customizable pre-printed consent forms: a solution in light of the Montgomery ruling.

    Science.gov (United States)

    Owen, Deborah; Aresti, Nick; Mulligan, Alex; Kosuge, Dennis

    2018-02-02

    This article presents an audit cycle supported quality improvement project addressing best practice in the consent process for lower limb arthroplasty which takes into account the new standard in surgical consent and the importance of material risks. 50 consecutive total hip and total knee replacement consent forms over a 3-month period were reviewed for legibility and completeness. Following the introduction of a new, pre-printed but customizable consent form the review process was repeated. The introduction of a customizable, pre-printed consent form that can be adjusted to reflect the individualized material risks of each patient increased legibility, reduced inappropriate human error variation and abolished the use of abbreviations and medical jargon. When used as part of an extended consent process, the authors feel that the use of pre-printed but customizable consent forms improves legibility, completeness and consistency and also provides the ability to highlight those complications that are of particular importance for that patient to satisfy the new accepted standard in surgical consent.

  14. Inventory and Evaluation of Engineering Cultural Resources: Montgomery to Gadsden, Alabama Coosa River, Alabama,

    Science.gov (United States)

    1981-03-01

    to retain some of its aesthetic quality. Important bridges were also being constructed outside of France. The Westminister Bridge (1738-50) was built... Legislative Session. It was eventually to connect the waters of Mobile Bay with the Coosa River at Wetumpka, and eventually with the Tennessee. The project...Bridge Act of 1927 were important legislative aids. The state act resulted in the construction of fifteen major bridges, including the attractive

  15. Final Environmental Assessment For Proposed Family Campground Expansion Maxwell Air Force Base, Montgomery County, Alabama

    Science.gov (United States)

    2013-03-27

    during Final EA preparation. Providing private address information with your comment is voluntary and such personal information will be kept confidential ...commercially available. 4.2 Commercial kitchen appliances shall be either ENERGY STAR®, FEMP designated or qualified for California Utilities Rebate Program... kitchen pre-rinse spray valves (PRSV) with low flow nozzles) i. Install or convert to only ENERGY STAR® Commercial Dishwashers j. Install or convert to

  16. The compleat lawyer - medical law as practical reasoning : doctrine, empiricism, and engagement / Jonathan Montgomery

    Index Scriptorium Estoniae

    Montgomery, Jonathan

    2012-01-01

    Ajakirjanumber on pühendatud briti meditsiiniõiguse professori Margaret Brazieri töödele ja tegevusele erinevatelt teemadel: patsiendi õigused meditsiiniliste otsuste langetamiseks, asendusemadus, biomeditsiin ja loote õiguslikust staatusest, abordist ja vastavast seadusandlusest Hispaanias, patsiendi autonoomiast

  17. Architect of Union Victory? Montgomery Meigs, Jomini, and Union Success in the American Civil War

    Science.gov (United States)

    2012-04-23

    Floyd, ultimately caused Captain Meigs to be “exiled” to the Tortugas in Florida.20 16 Russell F...Washington for the Tortugas late in 1860. There was a great deal of unrest as he travelled through the south to Florida. As he was settling into Fort

  18. Environmental Assessment for Proposed Demolition and Consolidation, Maxwell Air Force Base, Montgomery County, Alabama

    Science.gov (United States)

    2013-09-01

    51 3.11.2.2 SANITARY SEWER ...............................................................51 3.11.2.3 ELECTRICITY...72 4.2.11.2 SANITARY SEWER ...............................................................73 4.2.11.3...loam or sandy clay soils. The majority of the installation consists of the Amite-Cahaba association which is deep, well-drained, fine sandy loam

  19. Maxwell AFB, Montgomery, Alabama. Revised Uniform Summary of Surface Weather Observations (RUSSWO)

    Science.gov (United States)

    1974-09-19

    VISION GAS . MAY 00-02 09 3,8 90 3,8 499 7,7 .1 11.6 3150 ___03.05, 1.1 4,0 1__ __ 4t, 15t6 139, *1 24#7 3188 0o.o13l ,5 397 __ 3t7 10,8 17,6 1__ 1 2497...WINDDIRECTION AND SPEED i (FROM HOURLY OBSERVATIONS) i ( ..1AXWELL AF B A-AA/HMM15C)MIRY 37m,72 sr-P STA TIONl STATIO lolUNK Tgllil "Ol N CLADA NOPAll (IS T

  20. Validity of the definite and semidefinite questionnaire version of the Hamilton Depression Scale, the Hamilton subscale and the Melancholia Scale. Part I

    DEFF Research Database (Denmark)

    Hansen, Jesper Bent; Bech, Per

    2011-01-01

    , and their corresponding definite versions of the self-rating questionnaires DMQ and DHAM6 were accepted by the Rasch analysis, and only these four valid scales discriminated significantly between the effect of citalopram and placebo treatment. Our results are limited to patients with moderate depression. Two new self......-report scales with unparalleled construct validity, reliability, sensitivity, and convergent validity have been identified (DMQ and DHAM6). We have also identified a crucial importance of format for the means and variances of self-rating scales. These findings are of high practical and scientific value....

  1. Reminder of Lagrange-Hamilton formalism and of the corpuscular optics invariants; Rappel du formalisme de Lagrange-Hamilton et sur les invariants de l'optique corpusculaire

    Energy Technology Data Exchange (ETDEWEB)

    Griess, F.

    1958-03-14

    Hamiltonian formalism - Canonical transformations - Invariants of Liouville, Helmholtz-Lagrange, Busch, Stoermer and Lagrange - Synchrotron's Hamiltonian - Betatron oscillation damping. (author) [French] Formalisme Hamiltonien. Transformations canoniques. Invariants de Liouville, Helmholtz-Lagrange, Busch, Stoermer et Lagrange, Hamiltonien pour le synchrotron, Amortissement des oscillations betatrons (auteur)

  2. Hamilton on surnud, tema mõju mitte : in memoriam Richard Hamilton (24. II 1922 - 13. IX 2011) / Kadri Karro ; kommenteerinud Eha Komissarov, Sirje Helme, Jaak Kangilaski

    Index Scriptorium Estoniae

    Karro,Kadri

    2011-01-01

    Briti kunstniku Richard Hamiltoni (1922 - 2011) loomingust eesti kunstiteadlaste Eha Komissarovi, Sirje Helme ja Jaak Kangilaski pilgu läbi. Lähemalt 1956. aastal valminud kollaažist "Mis teeb tänapäeva kodud nii eriliseks, nii meeldivaks?"

  3. Schaum's outline of theory and problems of Lagrangian dynamics with a treatment of Euler's equations of motion, Hamilton's equations and Hamilton's principle

    CERN Document Server

    Wells, Dare A

    1967-01-01

    The book clearly and concisely explains the basic principles of Lagrangian dynamicsand provides training in the actual physical and mathematical techniques of applying Lagrange's equations, laying the foundation for a later study of topics that bridge the gap between classical and quantum physics, engineering, chemistry and applied mathematics, and for practicing scientists and engineers.

  4. Geographic List of Prime Contract Awards. Oct 92-Sep 93. FY 93. (Amos, Kentucky-Montgomery County, Maryland). Part 6

    Science.gov (United States)

    1994-03-01

    r 11 c I0-eJI C1 31 00000P0) 0 (icc C) Cr) M 0 W( D(DE DW D0)o I o0)0 II.’I1)cc jinI 11 ) C\\LC\\m NA NI C111 Mr (’*4 Y MCJMMMMM (nr (YiC ) (ici MCici...0 00 0 0 III0-Ic14򒰌 OW 000 00 00 000 00 00 000> 00 0 00 11 1 l-4N II 1 N N, NN N 4 N NNN > II 10-i- 11 >- z co11111 - I\\ jINI ,-t 0 11 N N 00 Nc 4ɚ...I 0011C U.L 11 c I caoc II 00 11 E I Gao 0r, 1 -- -I .- ---- -- - - - - - - -- ----- 114- I COLD4l II 000000000000000000000000000000000000000000 00 1

  5. 76 FR 71125 - Caddo Valley Railroad Company-Abandonment Exemption-in Clark, Pike, and Montgomery Counties, AR

    Science.gov (United States)

    2011-11-16

    ... Abandonments to abandon the portion of the Norman Branch Line extending between milepost 447, near Antoine, to... feeder line statute at 49 U.S.C. 10907. See Caddo Antoine & Little Mo. R.R.--Feeder Line Acquis.--Ark...

  6. 78 FR 61871 - Grenada Railway, LLC-Rail Line in Grenada, Montgomery, Carroll, Holmes, Yazoo and Madison...

    Science.gov (United States)

    2013-10-04

    ... the Surface Transportation Board will hold a public meeting concerning the rail line embargo at issue... the effects of the embargo. DATES: Date/Location: The public meeting will take place on Friday... lawfulness of an embargo GRYR imposed on a portion of the Line in 2011.\\1\\ In doing so, the Board directed...

  7. Bringing Black History Home: Oral Sketches of the Black Experience from Africa to Montgomery to Bedford-Stuyvesant.

    Science.gov (United States)

    Levine, Richard

    This guide describes how to implement an interdisciplinary black history project designed to explore black experiences through a combination of personal anecdotes and text research. The program was designed by a teacher at Satellite East Junior High School in Brooklyn (New York). An introduction gives an overview of the structure and aims of the…

  8. Histomorphological and mucin histochemical study of the alimentary canal of pangas catfish, Pangasius pangasius (Hamilton 1822

    Directory of Open Access Journals (Sweden)

    Javd Sadeghinezhad

    2017-06-01

    Full Text Available The present study describes the histological and mucin histochemical properties of the alimentary canal (AC of the pangas catfish, Pangasius pangasius. The results revealed that the mucosa of the oesophagus was lined by a stratified epithelium containing chloride cells and taste buds which suggested mechanic, gustatory and physiologic roles of the oesophagus in this species. The stomach mucosa was lined by a simple columnar epithelium. The lamina propria-submucosa in cardiac and fundic stomach contained gastric glands. The pyloric stomach had the thickest muscularis layer among all the parts of the AC. The villi showed the maximum height and width in the middle intestine. The tunica muscularis and serosa showed the thinnest thickness among all parts of AC. The mucin histochemistry showed that the goblet cells of oesophagus and intestine contained both neutral and acidic with carboxylated and sulfated mucins and there was not acidic mucins in epithelial cells of the stomach.

  9. Data acquisition system for the Hamilton Standard W2 Electron Beam Welder

    International Nuclear Information System (INIS)

    Hopwood, J.

    1979-06-01

    A data acquisition system has been designed which will perform on-line weld-parameter sampling. It is a microprocessor-based program controller and calculator. The parameters sampled are beam current, accelerating voltage, focus-coil current, workpiece rpm, and filament voltage. Sampling in analog form occurs in pre-selected angular-rotation increments from 1 to 9 degrees. There are three data printout options: (A) all data displayed; (B) only out-of-tolerance values displayed; and (C) differences between nominal and sampled values in excess of preselected error bands displayed. A magnetic tape cartridge unit allows long-term data storage and easy retrieval. This report is a manual for system operation. It also describes the design--logic principles, circuitry, and programming--in detail

  10. Fecundity and gonadosomatic index of Glossogobius giuris (Hamilton, 1822 from the Payra River, Patuakhali, Bangladesh

    Directory of Open Access Journals (Sweden)

    Animesh Roy

    2014-08-01

    Full Text Available Glossogobius giuris were collected during March to September 2013 from the Payra river to estimate the length-weight relationship with relative condition factor (Kn, fecundity, gonadosomatic index (GSI and relation between fecundity and other parameters. The length-weight relationship was found to be Log W= 2.667 Log TL – 1.805 in male and Log W = 2.931 Log TL – 2.040 in female. The mean Kn were found to be 1.02±0.155 for male and 0.97±0.276 for female which indicates satisfactory condition of the fish population. The mean relative fecundity was ranged from 88495 to 264104 with a mean value of 171581±17855, having a average total length of 21.21±0.44 cm, body weight 70.22±4.62 g and gonad weight 2.74±0.31 g. The relationships among the fecundity, the total length, body weight, gonad weight were found to be linear and positively correlated. The mean GSI value was 3.42±0.33 and the highest GSI value was recorded 9.34±0.71 in the month of September. This study will help to introduce this species in sustainable aquaculture through proper management and for the development of induced breeding technique.

  11. Lead concentrations in fresh water, muscle, gill and liver of catla catla (hamilton) from keenjhar lake

    International Nuclear Information System (INIS)

    Korai, A.L.; Sahato, G.A.

    2008-01-01

    This study of the abundance and distribution of lead in water and freshwater fish Catla catla (Ham.) from Keenjhar Lake was conducted during January 2003 to December 2005. The lead content was determined in water and in muscle, gill and liver tissue of Catla catla (Ham.) by using a graphite furnace atomic absorption spectrometry. The lead concentrations in water samples were in the range of 0.076 and 0.225 macro g L-1 during the years of 2003, 2004 and 2005. The lead concentrations in the tissues of Catla catla (Ham.) varied, with liver > gill > muscle. The concentrations in muscle, gill and liver were in the range of 0.7-2.39 micro g g/sub -1/, 0.74-2.25 micro g g/sub -1/ and 0.89-2.68 micro g g/sub -1/ (dry weight) during 2003, 2004 and 2005. 9.87 % did not exceed the UK limit of 1.0 micro g g/sub -1/ (1979), 45.67 % were lower than the (USFDA) level of 1.3 micro g g/sub -1/ (USEPA 1997) and remaining 44.46 % were well below than 4.88 micro g g/sub -1/ (USEPA 1990). The levels in the water samples were also below the permissible level of less then 50 micro g L/sub -1/ recommended by (WHO 1984). (author)

  12. Dynamic Programming Algorithms for Planning and Robotics in Continuous Domains and the Hamilton-Jacobi Equation

    Science.gov (United States)

    2008-09-22

    function essentially binary • Value function measures cost to go – Solution of Eikonal equation – Gradient determines optimal control typical laser...of nodes – Dijkstra’s algorithm is essentially unchanged • Continuous space – Static HJ PDE no longer reduces to the Eikonal equation – Gradient of ϑ...bounded: ||·||1 • If action is bounded in ||·||p, then value function is solution of “ Eikonal ” equation ||ϑ(x)||p* = c(x) in the dual norm p* – p = 1

  13. Proposed Bak Stabilization Tennessee River, River Mile 466.2 - 466.5 Hamilton County, Tennessee

    Science.gov (United States)

    2013-04-01

    aegyptium ). Vegetation along the bank consists of honey locust (Gleditsia tricanthos), sycamore (Platanus occidentalis), kudzu (Pueraria lobata...Adverse effects comprise, but are not necessarily limited to, the following: (a) death or injury to one or more individuals that results from activities...exclusive privileges, nor does it authorize any injury to private property or any invasion of personal rights, nor any infringement of federal, State

  14. The Wigner distribution function and Hamilton's characteristics of a geometric-optical system

    NARCIS (Netherlands)

    Bastiaans, M.J.

    1979-01-01

    Four system functions have been defined for an optical system; each of these functions describes the system completely in terms of Fourier optics. From the system functions the Wigner distribution function of an optical system has been defined; although derived from Fourier optics, this Wigner

  15. Generation of viable progeny from dead brooders of endangered catfish Clarias magur (Hamilton, 1822

    Directory of Open Access Journals (Sweden)

    Sullip Kumar Majhi

    2017-10-01

    Full Text Available The obligatory air-breathing catfish Clarias magur is a prime candidate for aquaculture owing to its unique taste, high growth rate, and hardy nature. However, recently the IUCN has listed the species under the endangered category because the population has critically declined in the wild. The sexually mature C. magur brooders are often collected from their natural habitats for seed production in captivity. In many cases, the brooder dies due to handling injuries or confinement stress. In this study, we demonstrated that viable progeny could be generated from freshly dead sexually mature C. magur. Three hours after death, the gonads were excised, macroscopically examined and gamete viability was evaluated. Artificial fertilization was performed by mixing the sperm suspension with the eggs. Water was added after 1 min of mixing to activate the fertilization process. We observed 85%-93% fertilization success from gametes derived from dead donors as opposed to 90%-95% from those derived from live control donors. The embryos showed normal development and resulted in the generation of 88%-92% viable progeny, which was similar to the progeny derived from control donors (92%-93%. The results obtained in this study will have profound implications in enhancing the seed production of endangered C. magur and could potentially be applied to other key commercially or endangered fish species. Keywords: Biological sciences, Developmental biology, Zoology

  16. Health and Safety Plan Data Item A009. Hamilton Army Airfield, Novato, California

    Science.gov (United States)

    1990-11-01

    also positively or negatively effect the measured results. Calibration and maintenance will be performed in accordance with the manufacturer’s...allows reading of the scale and operation of the knobs. The sensors can be partially wrapped, keeping the sensor tip and discharge port clear. The...01111 a -1,1 "I NMw~ 0: a ’MaWsif0II A *t wo ON SWIMm SOL egj _’ ~ m e w - e m sm FLWAAw my wow" "Nw CA 1,~ On a- i M 7 EsuMe wow urn to etmime womo

  17. Delayed development of the Provost Viking ''C'' Pool formerly the Hamilton Lake Oilfield. [Canada

    Energy Technology Data Exchange (ETDEWEB)

    Bokman, J

    1970-06-01

    The Provost Viking ''C'' Pool has had an unusual development history. This history has consisted of several distinct stages covering a span of almost 20 yr from 1952 to 1970. Each stage was initiated by a change in concepts concerning the pool and changes in specific technological or economic factors. Examples of these are: modified views as to what constitutes an acceptable exploration target (thin pay), implementation of a new recovery method or production scheme for the area, cheaper well drilling and development costs, wider well spacing and the development of an inexpensive, reliable source of water for injection. This discussion is designed to illustrate how these changes in concepts and in technology can be effective in stimulating the development of new and regeneration of old prospects. They illustrate exceptionally well the interrelationship and interdependence of the various tools - exploration and development geology, production and reservoir engineering, land and economics - which are employed in the oil industry. They also should contain some lessons which are applicable to other situations.

  18. Gene expression in Catla catla (Hamilton) subjected to acute and protracted doses of gamma radiation

    Energy Technology Data Exchange (ETDEWEB)

    Anbumani, S., E-mail: aquatox1982@gmail.com; Mohankumar, Mary N., E-mail: marynmk@gmail.com

    2016-09-15

    Highlights: • Gamma radiation induced up- and down- regulation of cell cycle genes. • Protracted dose-rate induced gene up-regulation to facilitate cell survival. • bcl-2 gene facilitates repair at protracted dose and cell death at acute exposures. • gadd45α, cdk1 and bcl-2 genes work in concert to promote ‘repair’ and ‘death’ circuitries in fish blood cells. - Abstract: Studies on transcriptional modulation after gamma radiation exposure in fish are limited. Cell cycle perturbations and expression of apoptotic genes were investigated in the fish, Catla catla after acute and protracted exposures to gamma radiation over a 90 day period. Significant changes in gene expression were observed between day 1 and 90 post-exposure. Gamma radiation induced a significant down-regulation of target genes gadd45α, cdk1 and bcl-2 from day 1 to day 3 after protracted exposure, whereas it persists till day 6 upon acute exposure. From day 12 onwards, Gadd45α, cdk1 and bcl-2 genes were up-regulated following protracted exposure, indicating DNA repair, cell-cycle arrest and apoptosis. There exists a linear correlation between these genes (gadd45α – r = 0.85, p = 0.0073; cdk1 – r = 0.86, p = 0.0053; bcl-2 – r = 0.89, p = 0.0026) at protracted exposures. This is the first report on the dual role of bcl-2 gene in fish exposed to acute and protracted radiation and correlation among the aforementioned genes that work in concert to promote ‘repair’ and ‘death’ circuitries in fish blood cells.

  19. Gene expression in Catla catla (Hamilton) subjected to acute and protracted doses of gamma radiation

    International Nuclear Information System (INIS)

    Anbumani, S.; Mohankumar, Mary N.

    2016-01-01

    Highlights: • Gamma radiation induced up- and down- regulation of cell cycle genes. • Protracted dose-rate induced gene up-regulation to facilitate cell survival. • bcl-2 gene facilitates repair at protracted dose and cell death at acute exposures. • gadd45α, cdk1 and bcl-2 genes work in concert to promote ‘repair’ and ‘death’ circuitries in fish blood cells. - Abstract: Studies on transcriptional modulation after gamma radiation exposure in fish are limited. Cell cycle perturbations and expression of apoptotic genes were investigated in the fish, Catla catla after acute and protracted exposures to gamma radiation over a 90 day period. Significant changes in gene expression were observed between day 1 and 90 post-exposure. Gamma radiation induced a significant down-regulation of target genes gadd45α, cdk1 and bcl-2 from day 1 to day 3 after protracted exposure, whereas it persists till day 6 upon acute exposure. From day 12 onwards, Gadd45α, cdk1 and bcl-2 genes were up-regulated following protracted exposure, indicating DNA repair, cell-cycle arrest and apoptosis. There exists a linear correlation between these genes (gadd45α – r = 0.85, p = 0.0073; cdk1 – r = 0.86, p = 0.0053; bcl-2 – r = 0.89, p = 0.0026) at protracted exposures. This is the first report on the dual role of bcl-2 gene in fish exposed to acute and protracted radiation and correlation among the aforementioned genes that work in concert to promote ‘repair’ and ‘death’ circuitries in fish blood cells.

  20. Hamiltonization and Integrability of the Chaplygin Sphere in R^n

    OpenAIRE

    Jovanovic, Bozidar

    2009-01-01

    The paper studies a natural $n$-dimensional generalization of the classical nonholonomic Chaplygin sphere problem. We prove that for a specific choice of the inertia operator, the restriction of the generalized problem onto zero value of the SO(n-1)-momentum mapping becomes an integrable Hamiltonian system after an appropriate time reparametrization.

  1. Review of Arctic fox. Life at the top of the world, by Gary Hamilton

    OpenAIRE

    Ims, Rolf A.

    2009-01-01

    The Arctic fox is the only truly Arctic species among the terrestrial carnivorous mammals of the world. It is distributed across the circumpolar Arctic region. Like polar bears, Arctic foxes regularly traverse the pack ice of the polar basin, a fact that astonished Fridtjof Nansen during his attempt to reach the North Pole more than 100 years ago. However, despite its unique lifestyle, which in some respects is more fascinating than that of the polar bear, there has been no popular book (exce...

  2. Networked traffic state estimation involving mixed fixed-mobile sensor data using Hamilton-Jacobi equations

    KAUST Repository

    Canepa, Edward S.; Claudel, Christian G.

    2017-01-01

    Nowadays, traffic management has become a challenge for urban areas, which are covering larger geographic spaces and facing the generation of different kinds of traffic data. This article presents a robust traffic estimation framework for highways modeled by a system of Lighthill Whitham Richards equations that is able to assimilate different sensor data available. We first present an equivalent formulation of the problem using a Hamilton–Jacobi equation. Then, using a semi-analytic formula, we show that the model constraints resulting from the Hamilton–Jacobi equation are linear ones. We then pose the problem of estimating the traffic density given incomplete and inaccurate traffic data as a Mixed Integer Program. We then extend the density estimation framework to highway networks with any available data constraint and modeling junctions. Finally, we present a travel estimation application for a small network using real traffic measurements obtained obtained during Mobile Century traffic experiment, and comparing the results with ground truth data.

  3. 75 FR 62333 - Airworthiness Directives; Hamilton Sundstrand Propellers Model 247F Propellers

    Science.gov (United States)

    2010-10-08

    ...., Monday through Friday, except Federal holidays. The AD docket contains this proposed AD, the regulatory... that the 247F propeller blades, P/N 817370-1, S/Ns FR2449 to FR2958 inclusive, FR20010710 to FR20010722 inclusive, and FR20010723RT to FR20020127RT inclusive, manufactured since January 1999, might also have...

  4. 76 FR 7101 - Airworthiness Directives; Hamilton Sundstrand Propellers Model 247F Propellers

    Science.gov (United States)

    2011-02-09

    ..., except Federal holidays. The AD docket contains this AD, the regulatory evaluation, any comments received... blades part number (P/N) 817370-1, S/Ns FR2449 to FR2958 inclusive, FR20010710 to FR20010722 inclusive, and FR20010723RT to FR20020127RT inclusive, before December 31, 2010. We determined that those S/N...

  5. Hamilton and Zuk 1982, Earlé et al. 1991, Bennet et al. 1995, Jovani

    African Journals Online (AJOL)

    spamer

    hatching (Graczyk et al. 1994). ... Its success has been attributed to the ... Future success of avian blood parasites and/or ... rates (Trager 1939, Roberts 1968), but this does not happen ... The insects of sub-Antarctic Marion and Prince Edward.

  6. Effect of sublethal concentrations of zinc on reproduction in the zebrafish, Brachydanio rerio Hamilton--Buchanan

    Energy Technology Data Exchange (ETDEWEB)

    Speranza, A.W.; Seeley, R.J.; Seeley, V.A.; Perlmutter, A.

    1977-03-01

    Adult zebrafish, when held in water containing a threshold concentration (55 ppM) of zinc for a 9-day period in which the gametes were maturing, showed a delay in spawning. When spawning did occur, the experimental pairs of fish produced an average of 165 eggs of which only 21.1 percent were viable. In contrast, control pairs of fish produced an average of 434 eggs of which 90.2 percent were viable. In addition, survival of the eggs to hatching was significantly lower than in controls, the survival rate for the experimentals being 0.9 percent, that of the controls, 63.3 percent. The adverse effects on zebrafish of exposure to zinc can be reversed by returning the fish to a zinc-free environment.

  7. The kids at Hamilton Elementary School: Purposes and practices for co-opting science

    Science.gov (United States)

    Ortiz, Loaiza

    The purpose of this study was to explore youth's purposes and motivations for engaging in science through the lens of science practices. The construct of science practices allowed me to see science in youths' lives in a holistic way, shaped by social, political, historical, economic and cultural forces. The framework for understanding urban youths' science practices is grounded in the intersections of critical and feminist theory, sociocultural learning theories, especially as applied in research in urban science education, and recent work in critical literacy studies. As I explored the answers to my research questions---(1) When 5th grade youth, living in predominantly Latino communities struggling with urban poverty, engage in science how and why do they co-opt science in ways that result in changes in participation in science? (2) What are the science practices that facilitate youths' coopting of science? And how are those practices framed by context (school, out-of-school), content (LiFE curriculum), and funds of knowledge? (3) In what ways are science practices expressions of youths' scientific literacy? And (4) In what ways do youth use science practices as tools for expressing identities and agency?---I engaged in feminist ethnography with embedded case studies. Data were collected in 2004 in school and in out of school settings. I recorded numerous informal conversations, interviews, and observations both during after-school and students' regular science and non-science classes. Findings describe how and why students co-opted science for purposes that make sense for their lives. These purposes included gaining and activating resources, building and maintaining social relationships, bridging home and school knowledge, positioning themselves with authority, and constructing science identities. Findings also explored what practices facilitated youth's co-opting of science. I highlighted three practices: making ideas public, storytelling and prioritizing and using evidence. Finally, I present an in-depth analysis of the science practice of storytelling. Analysis revealed that students engaged in storytelling to facilitate co-opting of science by: allowing them to change the discourse of the science classroom, to seek legitimacy, and to position themselves with authority. I end with implications for urban science education, teacher education and for future research.

  8. Networked traffic state estimation involving mixed fixed-mobile sensor data using Hamilton-Jacobi equations

    KAUST Repository

    Canepa, Edward S.

    2017-06-19

    Nowadays, traffic management has become a challenge for urban areas, which are covering larger geographic spaces and facing the generation of different kinds of traffic data. This article presents a robust traffic estimation framework for highways modeled by a system of Lighthill Whitham Richards equations that is able to assimilate different sensor data available. We first present an equivalent formulation of the problem using a Hamilton–Jacobi equation. Then, using a semi-analytic formula, we show that the model constraints resulting from the Hamilton–Jacobi equation are linear ones. We then pose the problem of estimating the traffic density given incomplete and inaccurate traffic data as a Mixed Integer Program. We then extend the density estimation framework to highway networks with any available data constraint and modeling junctions. Finally, we present a travel estimation application for a small network using real traffic measurements obtained obtained during Mobile Century traffic experiment, and comparing the results with ground truth data.

  9. A review on Labeo calbasu (Hamilton with an emphasis on its conservation

    Directory of Open Access Journals (Sweden)

    Sandipan Gupta

    2015-12-01

    Full Text Available Labeo calbasu is a freshwater fish species and is the most important carp species next to three Indian Major Carps Labeo rohita, Catla catla and Cirrhinus mrigala. It is a popular food fish and also is admired as a sport fish. Recently this fish species has also made its entry in ornamental fish markets of India and abroad. In last few years, the natural populations of this fish species has seriously declined due to over fishing and other anthropological reasons. In India it has been reported as Lower Risk near Threatened and in Bangladesh as endangered species. Earlier number of works has been conducted on different aspects of Labeo calbasu including food and feeding habit and reproductive biology. This report has been prepared with a view to sum up all those previously documented information along with pointing out the missing information further study of which will be beneficial for its fishery. Apart from this, it has been tried to note down some possible measures which should be considered for its conservation.

  10. Data acquisition system for the Hamilton Standard W2 Electron Beam Welder

    Energy Technology Data Exchange (ETDEWEB)

    Hopwood, J.

    1979-06-01

    A data acquisition system has been designed which will perform on-line weld-parameter sampling. It is a microprocessor-based program controller and calculator. The parameters sampled are beam current, accelerating voltage, focus-coil current, workpiece rpm, and filament voltage. Sampling in analog form occurs in pre-selected angular-rotation increments from 1 to 9 degrees. There are three data printout options: (A) all data displayed; (B) only out-of-tolerance values displayed; and (C) differences between nominal and sampled values in excess of preselected error bands displayed. A magnetic tape cartridge unit allows long-term data storage and easy retrieval. This report is a manual for system operation. It also describes the design--logic principles, circuitry, and programming--in detail.

  11. Supersymmetric particles in N=2 superspace: phase space variables and Hamilton dynamics

    International Nuclear Information System (INIS)

    Azcarraga, J.A. de; Lukierski, J.

    1982-10-01

    We consider a reparametrization invariant model recently proposed based on the N-extended superPoincare group with central charges, which leads to trajectories on the N-extended Salam-Strathdee superspace. The case N=2 is discussed in detail. We show that the N=2 model is invariant under four real supergauge transformations generated by first class odd constraints which imply the Dirac equation. We introduce one bosonic (which fixes the reparametrization) and four real spinorial (which fix the supergauges) gauge conditions and calculate the Dirac brackets for the remaining unconstrained variables (x-vector,p-vector,thetasup(α),theta-barsup(α-dot)). The equations of motion are written in Hamiltonian form, with H varies as to Tr set containing Qsub(αi),Q-barsub(β-doti) and correspond to the Heisenberg equations of the (first) quantized theory. (author)

  12. Morphological observation and length-weight relationship of critically endangered riverine catfish Rita rita (Hamilton).

    Science.gov (United States)

    Amin, M R; Mollah, M F A; Taslima, K; Muhammadullah

    2014-01-15

    The experiment was conducted to investigate the morphological status of the critically endangered riverine catfish Rita rita using morphometric and meristic traits. About 158 species of Rita were collected from the old Brahmaputra river in Mymensingh district and were studied in the laboratory of the Fisheries Biology and Genetics Department, Bangladesh Agricultural University. Measurement of length and weight of Rita were recorded by using measuring scale and electric balance respectively. Significant curvilinear relationship existed between total length and other morphometric characters and between head length and other characters of the head. Relationships between total length and various body measurements of the fish were highly significant (p < 0.01) except the relationship between total length and pelvic fin length of male fish (p < 0.05). In case of meristic characters-dorsal fin rays, pelvic fin rays, pectoral fin rays, anal fin rays, caudal fin rays, number of vertebrae and branchiostegal rays were found to be more or less similar except slight differences. The values of condition factors (k) in the total length body-weight relationships for female and male were found to be 0.41 and 0.38, respectively. The mean values of relative condition factors (kn) were 1.0 and 1.005 for female and male, respectively.

  13. Modeling of a ring rosen-type piezoelectric transformer by Hamilton's principle.

    Science.gov (United States)

    Nadal, Clément; Pigache, Francois; Erhart, Jiří

    2015-04-01

    This paper deals with the analytical modeling of a ring Rosen-type piezoelectric transformer. The developed model is based on a Hamiltonian approach, enabling to obtain main parameters and performance evaluation for the first radial vibratory modes. Methodology is detailed, and final results, both the input admittance and the electric potential distribution on the surface of the secondary part, are compared with numerical and experimental ones for discussion and validation.

  14. Continuum mechanics and thermodynamics in the Hamilton and the Godunov-type formulations

    Science.gov (United States)

    Peshkov, Ilya; Pavelka, Michal; Romenski, Evgeniy; Grmela, Miroslav

    2018-01-01

    Continuum mechanics with dislocations, with the Cattaneo-type heat conduction, with mass transfer, and with electromagnetic fields is put into the Hamiltonian form and into the form of the Godunov-type system of the first-order, symmetric hyperbolic partial differential equations (SHTC equations). The compatibility with thermodynamics of the time reversible part of the governing equations is mathematically expressed in the former formulation as degeneracy of the Hamiltonian structure and in the latter formulation as the existence of a companion conservation law. In both formulations the time irreversible part represents gradient dynamics. The Godunov-type formulation brings the mathematical rigor (the local well posedness of the Cauchy initial value problem) and the possibility to discretize while keeping the physical content of the governing equations (the Godunov finite volume discretization).

  15. On the Connection between the Hamilton-Jacobi-Bellman and the Fokker-Planck Control Frameworks

    KAUST Repository

    Annunziato, Mario; Borzì , Alfio; Nobile, Fabio; Tempone, Raul

    2014-01-01

    appropriate assumptions it is shown that the two strategies are equivalent in the case of expected cost functionals, while the FokkerPlanck formalism allows considering a larger class of objectives. To illustrate the connection between the two control

  16. 77 FR 27272 - Environmental Impact Statement: Hamilton and Clermont Counties, OH

    Science.gov (United States)

    2012-05-09

    ... new rail transit corridor composed of four implementation segments, improved bus transit, various... and proposed Oasis Rail Line Segment 3 will involve more detailed engineering and environmental... congestion, improve safety and efficiency, provide operational capacity for bus transit, accommodate bike and...

  17. Hamilton's equations for a fluid membrane: axial symmetry

    Energy Technology Data Exchange (ETDEWEB)

    Capovilla, R [Departamento de Fisica, Centro de Investigacion y de Estudios Avanzados del IPN, Apdo Postal 14-740, 07000 Mexico, DF (Mexico); Guven, J [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, Apdo Postal 70-543, 04510 Mexico, DF (Mexico); Rojas, E [Facultad de Fisica e Inteligencia Artificial, Universidad Veracruzana, 91000 Xalapa, Veracruz (Mexico)

    2005-09-23

    Consider a homogeneous fluid membrane, or vesicle, described by the Helfrich-Canham energy, quadratic in the mean curvature. When the membrane is axially symmetric, this energy can be viewed as an 'action' describing the motion of a particle; the contours of equilibrium geometries are identified with particle trajectories. A novel Hamiltonian formulation of the problem is presented which exhibits the following two features: (i) the second derivatives appearing in the action through the mean curvature are accommodated in a natural phase space and (ii) the intrinsic freedom associated with the choice of evolution parameter along the contour is preserved. As a result, the phase space involves momenta conjugate not only to the particle position but also to its velocity, and there are constraints on the phase space variables. This formulation provides the groundwork for a field theoretical generalization to arbitrary configurations, with the particle replaced by a loop in space.

  18. Hamilton's Marbles or Jevon's Beans: A Demonstration of Miller's Magical Number Seven.

    Science.gov (United States)

    Shaffer, Leigh S.

    1982-01-01

    Describes a demonstration for college-level cognitive psychology classes of Miller's "Magical Number Seven" concept of the limitation of sensory capacity for processing information. Students report on the number of pennies they observed in a box after viewing the coins for two seconds. Demonstration results consistently support Miller's…

  19. Understanding geometric algebra Hamilton, Grassmann, and Clifford for computer vision and graphics

    CERN Document Server

    Kanatani, Kenichi

    2015-01-01

    Introduction PURPOSE OF THIS BOOK ORGANIZATION OF THIS BOOK OTHER FEATURES 3D Euclidean Geometry VECTORS BASIS AND COMPONENTS INNER PRODUCT AND NORM VECTOR PRODUCTS SCALAR TRIPLE PRODUCT PROJECTION, REJECTION, AND REFLECTION ROTATION PLANES LINES PLANES AND LINES Oblique Coordinate Systems RECIPROCAL BASIS RECIPROCAL COMPONENTS INNER, VECTOR, AND SCALAR TRIPLE PRODUCTS METRIC TENSOR RECIPROCITY OF EXPRESSIONS COORDINATE TRANSFORMATIONSHamilton's Quaternion Algebra QUATERNIONS ALGEBRA OF QUATERNIONS CONJUGATE, NORM, AND INVERSE REPRESENTATION OF ROTATION BY QUATERNION Grassmann's Outer Product

  20. Reminder of Lagrange-Hamilton formalism and of the corpuscular optics invariants

    International Nuclear Information System (INIS)

    Griess, F.

    1958-01-01

    Hamiltonian formalism - Canonical transformations - Invariants of Liouville, Helmholtz-Lagrange, Busch, Stoermer and Lagrange - Synchrotron's Hamiltonian - Betatron oscillation damping. (author) [fr

  1. 78 FR 3024 - Sam D. Hamilton Noxubee National Wildlife Refuge, MS; Intent To Prepare a Comprehensive...

    Science.gov (United States)

    2013-01-15

    ... an area for the ``conservation, management, and restoration of the fish, wildlife, and plant... ``for use as an inviolate sanctuary, or for any other management purpose, for migratory birds'' 16 U.S.C...

  2. 75 FR 6613 - Endangered and Threatened Wildlife and Plants; Listing with Designation of Critical Habitat for...

    Science.gov (United States)

    2010-02-10

    ... University Montgomery, 7440 East Drive, Montgomery, Alabama, at the Taylor Center in conference room 223... Auburn University Montgomery, Taylor Center-conference room 223, 7440 East Drive, Montgomery, Alabama. We...

  3. Effectiveness of oxytetracycline in reducing the bacterial load in rohu fish (Labeo rohita, Hamilton) under laboratory culture condition

    OpenAIRE

    Syed Ariful Haque; Md. Shaheed Reza; Md. Rajib Sharker; Md. Mokhlasur Rahman; Md. Ariful Islam

    2014-01-01

    Objective: To observe the effectiveness of most widely used antibiotic, oxytetracycline (OTC) in reducing the bacterial load in rohu fish under artificial culture condition in the laboratory. Methods: The experiment was conducted in the Faculty Fisheries, Bangladesh Agricultural University, Mymensingh-2202. The fish were reared in 8 aquaria where fish in 5 aquaria were used for replication of the treatment (experimental group) and fish in remaining 3 aquaria were considered...

  4. BIO-EXPLOITATION STATUS OF BOMBAY DUCK (Harpadon nehereus HAMILTON, 1822 ON TRAWL FISHERY IN TARAKAN WATERS

    Directory of Open Access Journals (Sweden)

    Duto Nugroho

    2015-06-01

    Full Text Available North Kalimantan Province, notably Tarakan City marine waters, is one of the important fishing ground in boundary area among Sulu Sulawesi Marine Ecoregion. It produces approximately 100 mt/annum of Bombay duck (Harpadon nehereus with valued of US$ 750,000. The sustainability of this fishery is a crucially concern given the following: substantial economic contribution, significant dependence of small-scale fishers on this species for their livelihoods. The fishing intensities considerable and growing threats to their habitats. To evaluate the vulnerability of individual species to over exploitation, the spawning potential ratio (SPR approach applied to describe the status of its existing fisheries. This approach provides the ability to determine fishing mortality as reference points to enhance its sustainability. The objective of this study is to understand this fish biomass resilience to harvesting. The calculated SPR based on the value of estimated length of first capture or Lc at 208 mm is equivalent to the SPR of 28%. With a base line of stocks are generally thought to risk recruitment declining when SPR <20%, recent finding indicated that the existing fishery can be generally described as nearly fully exploited. In recognition of this sector’s has an ecological importance and socio-economic significance, the sustainable development of Bombay duck fisheries should be initiated through developing local fishery committee to provide a their local fishery management plan.

  5. The Separation of Powers and the Judicial Functions in John Locke, Montesquieu e Hamilton, Madison e Jay.

    Directory of Open Access Journals (Sweden)

    Maurício Pires Guedes

    2015-12-01

    Full Text Available Currently there are emerging on the world political scene several movements that search for the foundation of a new philosophical paradigm related to new techniques of constitutional hermeneutics. This movement is the result of a long historical and political development whose immediate bases are directly attached to the consolidation of the modern state. This paper pretend to study the separation of powers, of diverse cultural matrices, from the judiciary function view, pretending to show these influences. From the perspective on history and law experience, these are the parameters we pretend to study, trying, at the end, an adequate understanding of institutional reality in which we live today.

  6. Pre-Construction Biogeochemical Analysis of Mercury in Wetlands Bordering the Hamilton Army Airfield (HAAF) Wetlands Restoration Site. Part 2

    National Research Council Canada - National Science Library

    Best, Elly P; Fredrickson, Herbert L; Hintelmann, Holger; Clarisse, Olivier; Dimock, Brian; Lutz, Charles H; Lotufo, Gui R; Millward, Rod N; Bednar, Anthony J; Furey, John S

    2007-01-01

    ...) is working with the San Francisco Basin Regional Water Board, California State Coastal Conservancy, and San Francisco Bay Conservation and Development Commission to reconstruct wetlands at the former...

  7. The time dependent Schrodinger equation revisited I: quantum field and classical Hamilton-Jacobi routes to Schrodinger's wave equation

    International Nuclear Information System (INIS)

    Scully, M O

    2008-01-01

    The time dependent Schrodinger equation is frequently 'derived' by postulating the energy E → i h-bar (∂/∂t) and momentum p-vector → ( h-bar /i)∇ operator relations. In the present paper we review the quantum field theoretic route to the Schrodinger wave equation which treats time and space as parameters, not operators. Furthermore, we recall that a classical (nonlinear) wave equation can be derived from the classical action via Hamiltonian-Jacobi theory. By requiring the wave equation to be linear we again arrive at the Schrodinger equation, without postulating operator relations. The underlying philosophy is operational: namely 'a particle is what a particle detector detects.' This leads us to a useful physical picture combining the wave (field) and particle paradigms which points the way to the time-dependent Schrodinger equation

  8. Pre-Construction Biogeochemical Analysis of Mercury in Wetlands Bordering the Hamilton Army Airfield (HAAF) Wetlands Restoration Site. Part 2

    Science.gov (United States)

    2007-09-01

    in the north ( agricultural runoff) to relative oligotrophic water in the south (Gilmour et al. 1998). The standing pool size of MeHg is the result...correlated to intermediate dissolved sulfate levels (50-100 µM) derived from sulfur added to agricultural fields in the north (Gilmour et al. 1998). This...and Cd in porewaters by DGT. Geochim. Cosmochim. Acta 59:4181-4192. Zhang, H., and W. Davison. 1999. Diffusional characteristics of hydrogels used in

  9. The influence of magnetic field on the spatial orientation in zebrafish Danio rerio (Hamilton and roach Rutilus rutilus (L.

    Directory of Open Access Journals (Sweden)

    Anastasia A. Batrakova

    2015-10-01

    This is the first study on the use of GMF for orientation in R. rutilus from a natural population. Our results confirm the presence of magnetosensitivity in roach. At the same time, the preferred direction in GMF matched the direction to the mouth of the channel where the fish were caught. It is possible that fish stressed by experimental manipulations have tried to “leave” the experimental arena in the usual direction of escape to the deep-water part of reservoir. Figure 1. Bimodal distribution of preferred directions in zebrafish by the reversal of vertical (a, horizontal (b, both vertical and horizontal (c components of GMF, and by the rotation of the horizontal component by 90 degrees clockwise (d. Distributions of preferred directions in control conditions (GMF for each experiment are given under corresponding diagrams (e, f, g, h. Figure 2. Distribution of preferred directions of roach in a GMF (a and the rotation of the horizontal component of the GMF by 90 degrees clockwise (b. Sample area with designation of the direction of the channel to the Rybinsk Reservoir (c. Asterisk shows the point of sampling.

  10. An investigation into the pricing methods used by small and medium-sized enterprises / Hamilton Tshegofatso Gape

    OpenAIRE

    Gape, Hamilton Tshegofatso

    2007-01-01

    This thesis investigates the pricing methods used by small and medium-sized enterprises (SMEs). Prices are a key determinant of demand which influences revenue and in turn the business' profits. A business may fail if products and services are priced incorrectly. Pricing decision is, therefore, one of the critical success factors of a business, including SMEs. There is consensus widely disseminated in the textbook literature, that successful pricing can only be achieved when...

  11. Fluctuating asymmetry in evaluating the developmental instability of Glossogobius giuris (Hamilton, 1822 from Lake Mainit, Surigao del Norte, Philippines

    Directory of Open Access Journals (Sweden)

    C.C.D.Joseph

    2016-06-01

    Full Text Available This study was conducted to assess the status of Lake Mainit by using fluctuating asymmetry in the populations of Glossogobius giuris. A total of 200 G. giuris was collected with 100 per sex. All the samples were placed in a flat styrofoam for the pinning of its fins to make it wider and to clearly see the samples point of origin for the land-marking process. 10% Formalin was applied in all the fins of the fish samples to make it hardened using a small brush. Twenty (20 landmarks were used to analyze the body shape of the fish. Several studies proved that FA can be used to directly assess water quality and the overall status of the ecosystem. Using thin-plate spline (TPS series, landmark analyses were obtained and subjected to Symmetry and Asymmetry in Geometric Data (SAGE software. Results in Procrustes ANOVA showed that individual symmetry showed a highly significant difference (P = 0.00 as well as Sides (Directional Asymmetry and Interaction (Fluctuating Asymmetry in the study area. All the samples showed FA in both sexes. The results of Principal Component Scores displayed a higher percentage in female (69.2797% than male (63.9214% from Lake Mainit. Variations are almost found in all the body part of the goby in female and male gobies except for anterior insertion of second dorsal fin and superior margin of the preoperculum. Females have a higher fluctuating asymmetry than in males. Females spawn and males protect the eggs from any predators. In this case, females are more susceptible to stress because they have to forage in order to compensate the energy used up during spawning. Males are less susceptible because they usually stay on the nesting ground, and don't have to cover far distances in finding food. This study validates the use of FA in determining the status of the fishes caught connecting to what the status of the environment is based on the result.

  12. GENETIC DIVERSITY OF WILD AND FARMED KALIBAUS (Labeo calbasu, Hamilton, 1822 BY RAPD ANALYSIS OF THE GENOMIC DNA

    Directory of Open Access Journals (Sweden)

    M.G. Mostafa

    2009-04-01

    Full Text Available Genetic diversity of two wild Kalibaus, Labeo calbasu populations and one hatchery stock was studied using random amplified polymorphic DNA (RAPD method. The three 10–mer random primers (OPA01, OPB02 and OPC03 yielded a total of 26 reproducible and consistently scorable RAPD bands of which 15 (57.69% were considered as polymorphic (P95 indicating a high level of genetic variation in all the studied populations. Among the three populations, Padma population shows low level of genetic diversity (0.1238 compared to other two and it might be caused by habitat degradation in many ways which ultimately affects the genetic variation of Kalibaus. The UPGMA dendrogram based on Nei’s (1972 original measures of genetic distance (D indicated the segregation of two wild and hatchery populations of L. calbasu into two distinct clusters: the Hatchery and Padma populations produced one cluster whereas the Jamuna population belonged to another cluster. This indicates that hatchery brood stock is derived from Padma River. Nevertheless, the preliminary study revealed that RAPD technique could be an effective tool in the assessment of population genetic structure of Kalibaus.

  13. Intestinal absorption and distribution of 14C-palmitic acid in an young Indian freshwater major carp, Labeo rohita (Hamilton)

    International Nuclear Information System (INIS)

    Sinha, G.M.; Chakrabarti, P.

    1983-01-01

    The mechanism of absorption and distribution of radioactive lipids in the various regions of the intestine and hepatopancreas of young Labeo rohita (Ham.) was investigated after feeding with small-sized earthworms (Pheretima posthuma), preinjected with 14 C-Palmitic acid. Dietary free fatty acids were mainly absorbed in the various regions (anterior, middle and posterior) of the intestine-the absorption capacity, however, varying greatly from region to region. The absorption of free fatty acids through the luminal brush border of the various regions of the intestine started at 24 hr of post-feeding (h.p.f.) with labelled diet and recorded its peak during 32 +- 2 h.p.f. However, middle intestine was found to be more active for such absorption than the other two regions (anterior and posterior). Incorporation of labelled Palmitic acid in the columnar epithelial cells and its subsequent transportation in the hepatic tissues, via lymphatic systems took place with in a short interval after absorption. However, absorption was completed within 40 h.p.f. when deposition of radioactive lipids was found to be maximum in the columnar epithelial cells of the various regions of the intestine and hepatic tissues. (author)

  14. Effectiveness of oxytetracycline in reducing the bacterial load in rohu fish (Labeo rohita, Hamilton under laboratory culture condition

    Directory of Open Access Journals (Sweden)

    Syed Ariful Haque

    2014-04-01

    Full Text Available Objective: To observe the effectiveness of most widely used antibiotic, oxytetracycline (OTC in reducing the bacterial load in rohu fish under artificial culture condition in the laboratory. Methods: The experiment was conducted in the Faculty Fisheries, Bangladesh Agricultural University, Mymensingh-2202. The fish were reared in 8 aquaria where fish in 5 aquaria were used for replication of the treatment (experimental group and fish in remaining 3 aquaria were considered as a control (Control group. OTC was fed to the fish in the experimental aquarium at the rate of 2 g/kg through diet twice daily whereas fish reared under control condition was given feed without antibiotic for 20 d and bacterial content in the aquarium water, gills, skin and intestine of fish were estimated at every alternative day after onset of the experiment. Results: Rearing the fish with OTC treated feed resulted in gradual decrease of bacterial load in the aquarium water, gills, intestine and skin of the fish whereas the content remain unchanged or little increased in the control group. Water quality parameters such as dissolved oxygen, pH and total hardness were within the suitable range in the experimental aquarium but not in control aquaria throughout the experimental period. Conclusions: These results suggest that OTC could be a potential antibiotic to reduce the bacterial load in fish and can be used commercially for maintaining the fish health in aquarium conditions.

  15. Preconstruction Biogeochemical Analysis of Mercury in Wetlands Bordering the Hamilton Army Airfield (HAAF) Wetlands Restoration Site. Part 3

    Science.gov (United States)

    2009-12-01

    but not included in the analyzed samples, were zooplankton, bacteria, and larvae for the Asian clam and mysids for the shrimp (Table 5-4). The...Asian clam, shrimp , goby) may contribute the most, while the central role of detritus-associated MeHg has to be further explored. The Questions and...Asian clam) Bay 1 -20.9 (-) 11.6 (-) 13.3 (-) Shrimp sp. Bay 6 -19.6 (0.4) 15.4 (1.6) 14.7 (1.4) Carcinus maenas (European green crab) Bay

  16. Expression Pattern of Myogenic Regulatory Transcription Factor mRNAs in the Embryo and Adult Labeo rohita (Hamilton, 1822

    Directory of Open Access Journals (Sweden)

    Archya Sengupta

    2014-01-01

    Full Text Available Understanding the regulation of skeletal muscle development is important to meet the increasing demand of Indian major carp Labeo rohita. Myogenic regulatory factors (MRFs along with myocyte specific enhancer factor 2 (MEF2 play the pivotal role in the determination and differentiation of skeletal muscle. The majority of skeletal muscle genes require both MRFs and MEF2 family members to activate their transcription. In this study, the expression pattern of MyoD, myf-5, myogenin, and MEF2A was observed from 6 h after fertilization to 12 months of age using semiquantitative RT-PCR as well as real-time PCR method. MyoD and myf-5 mRNAs were expressed at high level at the early embryonic stages. Myogenin and MEF2A were expressed after MyoD and myf-5 and remained active up to adult stage. Expression of MyoD was lower than that of Myf-5 after the 5th month. Partial sequencing of MyoD, myf-5, and MEF2A was done to draw phylogeny. In phylogenetic study, Labeo MyoD, MEF2A and myf-5 were found to be closely related to those of common carp. The present investigation suggests that the four transcription factors play pivotal role in the regulation of muscle growth of Labeo rohita in an overlapping and interconnected way.

  17. Cryopreservation of sperm of an indigenous endangered fish species Nandus nandus (Hamilton, 1822) for ex-situ conservation.

    Science.gov (United States)

    Sarder, M Rafiqul Islam; Sarker, M F Monowar; Saha, Shankar K

    2012-12-01

    This study dealt with the development of cryopreservation protocol for Nandus nandus, which entailed a number of experiments. Sperm was collected by sacrificing males. The collected sperm was suspended in extenders. Activation of sperm motility was evaluated in different osmolalities of NaCl. Motility of sperm decreased as the osmolality of the extender increased and was completely inhibited at almost 319 mOs mol/kg. To evaluate the toxicity of cryoprotectant, sperm was incubated with DMSO, methanol and ethanol at 5%, 10% and 15% concentrations, respectively, for 5-35 min. Five and ten percent of cryoprotectants produced better motility during 5 and 10 min incubation. Sperm incubated with 15% cryoprotectant seemed to be toxic and this concentration was excluded in the subsequent trials. Three extenders, namely, Alsever's solution, egg-yolk citrate and urea egg-yolk and three cryoprotectants, DMSO, methanol and ethanol were employed to preserve the sperm. Alsever's solution with 10% DMSO showed best performance producing 90.0±1.8% and 75.0±2.5% equilibration and post-thaw motility followed by that of 82.5±4.2% and 62.5±5.5% with Alsever's solution plus methanol, respectively. Between two diluents, sperm preserved with Alsever's solution plus DMSO produced highest fertilization (76.7±3.3%) and hatching (43.8±7.9%) while fresh sperm yielded 83.3±6.7% and 64.0±10.4% fertilization and hatching, respectively. The protocol developed through the study can be applied for long-term conservation of genetic materials of the endangered fish N. nandus and the cryopreserved sperm can be used in artificial breeding for generating new individuals. Copyright © 2012 Elsevier Inc. All rights reserved.

  18. Serous goblet cells: the protein secreting cells in the oral cavity of a catfish, Rita rita (Hamilton, 1822) (Bagridae, Siluriformes).

    Science.gov (United States)

    Yashpal, Madhu; Mittal, Ajay Kumar

    2014-02-01

    Serous goblet cells in the oral epithelium of Rita rita are characterized by the presence of distinct eosinophilic granules occupying large parts of the cytoplasm. In R. rita, a range of histochemical results reveal that these cells are involved in proteinaceous secretions, and thus likely contribute to various functions analogous to those of mammalian saliva. The secretions of these cells have also been associated with specific functions and are discussed in relation to their physiological importance with special reference to their roles in lubrication, alteration in viscosity, various functions of mucus such as handling, maneuvering and driving of food items toward the esophagus, maintaining taste sensitivity and protection of the oral epithelium. In addition, the serous goblet cells may also be considered as the primary defensive cell of the oral epithelium of R. rita. The results significantly add to very limited set of literature on the serous goblet cells and provide noteworthy information on the mucous secretions in the oral cavity of fish. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Algorithm for Overcoming the Curse of Dimensionality for Certain Non-convex Hamilton-Jacobi Equations, Projections and Differential Games

    Science.gov (United States)

    2016-05-01

    0.5 × 10−8. Our algorithm is implemented in C++ on an 1.7 GHz Intel Core i7-4650U CPU. Linear algebra packages BLAS [40] and LAPACK [41] are used to...subproblems. Our approach is expected to have wide applications in continuous dynamic games, control theory problems, and elsewhere. Mathematics...differential dynamic games, control theory problems, and dynamical systems coming from the physical world, e.g. [11]. An important application is to

  20. Complete mitochondrial genome sequence of Indian medium carp, Labeo gonius (Hamilton, 1822) and its comparison with other related carp species.

    Science.gov (United States)

    Behera, Bijay Kumar; Kumari, Kavita; Baisvar, Vishwamitra Singh; Rout, Ajaya Kumar; Pakrashi, Sudip; Paria, Prasenjet; Jena, J K

    2017-01-01

    In the present study, the complete mitochondrial genome sequence of Labeo gonius is reported using PGM sequencer (Ion Torrent). The complete mitogenome of L. gonius is obtained by the de novo sequences assembly of genomic reads using the Torrent Mapping Alignment Program (TMAP) which is 16 614 bp in length. The mitogenome of L. gonius comprised of 13 protein-coding genes, 22 tRNAs, 2 rRNA genes, and D-loop as control region along with gene order and organization, being similar to most of other fish mitogenomes of NCBI databases. The mitogenome in the present study has 99% similarity to the complete mitogenome sequence of Labeo fimbriatus, as reported earlier. The phylogenetic analysis of Cypriniformes depicted that their mitogenomes are closely related to each other. The complete mitogenome sequence of L. gonius would be helpful in understanding the population genetics, phylogenetics, and evolution of Indian Carps.

  1. Complete mitochondrial genome of threatened mahseer Tor tor (Hamilton 1822) and its phylogenetic relationship within Cyprinidae family.

    Science.gov (United States)

    Pavan-Kumar, A; Raman, Sudhanshu; Koringa, Prakash G; Patel, Namrata; Shah, Tejas; Singh, Rajeev K; Krishna, Gopal; Joshi, C G; Gireesh-Babu, P; Chaudhari, Aparna

    2016-12-01

    The mahseers (Tor, Neolissochilus and Naziritor) are an important group of fishes endemic to Asia with the conservation status of most species evaluated as threatened. Conservation plans to revive these declining wild populations are hindered by unstable taxonomy. Molecular phylogeny studies with mitochondrial genome have been successfully used to reconstruct the phylogenetic tree and to resolve taxonomic ambiguity. In the present study, complete mitochondrial genome of Tor tor has been sequenced using ion torrent next-generation sequencing platform with coverage of more than 1000 x. Comparative mitogenome analysis shows higher divergence value at ND1 gene than COI gene. Further, occurrence of a distinct genetic lineage of T. tor is revealed. The phylogenetic relationship among mahseer group has been defined as Neolissochilus hexagonolepis ((T. sinensis (T. putitora, T. tor), (T. khudree, T. tambroides)).

  2. Dynamical and geometric aspects of Hamilton-Jacobi and linearized Monge-Ampère equations VIASM 2016

    CERN Document Server

    Tran, Hung

    2017-01-01

    Consisting of two parts, the first part of this volume is an essentially self-contained exposition of the geometric aspects of local and global regularity theory for the Monge–Ampère and linearized Monge–Ampère equations. As an application, we solve the second boundary value problem of the prescribed affine mean curvature equation, which can be viewed as a coupling of the latter two equations. Of interest in its own right, the linearized Monge–Ampère equation also has deep connections and applications in analysis, fluid mechanics and geometry, including the semi-geostrophic equations in atmospheric flows, the affine maximal surface equation in affine geometry and the problem of finding Kahler metrics of constant scalar curvature in complex geometry. Among other topics, the second part provides a thorough exposition of the large time behavior and discounted approximation of Hamilton–Jacobi equations, which have received much attention in the last two decades, and a new approach to the subject, the n...

  3. Field lines of gravity, their curvature and torsion, the Lagrange and the Hamilton equations of the plumbline

    Directory of Open Access Journals (Sweden)

    E. W. Grafarend

    1997-06-01

    Full Text Available The length of the gravitational field lines/of the orthogonal trajectories of a family of gravity equipotential surfaces/of the plumbline between a terrestrial topographic point and a point on a reference equipotential surface like the geoid í also known as the orthometric height í plays a central role in Satellite Geodesy as well as in Physical Geodesy. As soon as we determine the geometry of the Earth pointwise by means of a satellite GPS (Global Positioning System: «global problem solver» we are left with the problem of converting ellipsoidal heights (geometric heights into orthometric heights (physical heights. For the computation of the plumbline we derive its three differential equations of first order as well as the three geodesic equations of second order. The three differential equations of second order take the form of a Newton differential equation when we introduce the parameter time via the Marussi gauge on a conformally flat three-dimensional Riemann manifold and the generalized force field, the gradient of the superpotential, namely the modulus of gravity squared and taken half. In particular, we compute curvature and torsion of the plumbline and prove their functional relationship to the second and third derivatives of the gravity potential. For a spherically symmetric gravity field, curvature and torsion of the plumbline are zero, the plumbline is straight. Finally we derive the three Lagrangean as well as the six Hamiltonian differential equations of the plumbline, in particular in their star form with respect to Marussi gauge.

  4. Retina Image Analysis and Ocular Telehealth: The Oak Ridge National Laboratory-Hamilton Eye Institute Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Karnowski, Thomas Paul [ORNL; Giancardo, Luca [ORNL; Li, Yaquin [University of Tennessee, Knoxville (UTK); Tobin Jr, Kenneth William [ORNL; Chaum, Edward [University of Tennessee, Knoxville (UTK)

    2013-01-01

    Automated retina image analysis has reached a high level of maturity in recent years, and thus the question of how validation is performed in these systems is beginning to grow in importance. One application of retina image analysis is in telemedicine, where an automated system could enable the automated detection of diabetic retinopathy and other eye diseases as a low-cost method for broad-based screening. In this work we discuss our experiences in developing a telemedical network for retina image analysis, including our progression from a manual diagnosis network to a more fully automated one. We pay special attention to how validations of our algorithm steps are performed, both using data from the telemedicine network and other public databases.

  5. El operador generalizado de Hamilton-Morse, sus funciones propias y la función de Green

    Directory of Open Access Journals (Sweden)

    Hernán Estrada

    1992-07-01

    Full Text Available For the generalizad. Morse potencial it is possible to calculate the exact wave functions for the bound and continuum states as well as the Green function associated with the Hamiltonian.

  6. Antidepressant Effects of a Single Dose of Ayahuasca in Patients With Recurrent Depression: A SPECT Study.

    Science.gov (United States)

    Sanches, Rafael Faria; de Lima Osório, Flávia; Dos Santos, Rafael G; Macedo, Ligia R H; Maia-de-Oliveira, João Paulo; Wichert-Ana, Lauro; de Araujo, Draulio Barros; Riba, Jordi; Crippa, José Alexandre S; Hallak, Jaime E C

    2016-02-01

    Ayahuasca is an Amazonian botanical hallucinogenic brew which contains dimethyltryptamine, a 5-HT2A receptor agonist, and harmine, a monoamine-oxidase A inhibitor. Our group recently reported that ayahuasca administration was associated with fast-acting antidepressive effects in 6 depressive patients. The objective of the present work was to assess the antidepressive potentials of ayahuasca in a bigger sample and to investigate its effects on regional cerebral blood flow. In an open-label trial conducted in an inpatient psychiatric unit, 17 patients with recurrent depression received an oral dose of ayahuasca (2.2 mL/kg) and were evaluated with the Hamilton Rating Scale for Depression, the Montgomery-Åsberg Depression Rating Scale, the Brief Psychiatric Rating Scale, the Young Mania Rating Scale, and the Clinician Administered Dissociative States Scale during acute ayahuasca effects and 1, 7, 14, and 21 days after drug intake. Blood perfusion was assessed eight hours after drug administration by means of single photon emission tomography. Ayahuasca administration was associated with increased psychoactivity (Clinician Administered Dissociative States Scale) and significant score decreases in depression-related scales (Hamilton Rating Scale for Depression, Montgomery-Åsberg Depression Rating Scale, Brief Psychiatric Rating Scale) from 80 minutes to day 21. Increased blood perfusion in the left nucleus accumbens, right insula and left subgenual area, brain regions implicated in the regulation of mood and emotions, were observed after ayahuasca intake. Ayahuasca was well tolerated. Vomiting was the only adverse effect recorded, being reported by 47% of the volunteers. Our results suggest that ayahuasca may have fast-acting and sustained antidepressive properties. These results should be replicated in randomized, double-blind, placebo-controlled trials.

  7. Crime

    Data.gov (United States)

    Montgomery County of Maryland — Updated daily postings on Montgomery County’s open data website, dataMontgomery, provide the public with direct access to crime statistic databases - including raw...

  8. Crash Reporting - Incidents Data

    Data.gov (United States)

    Montgomery County of Maryland — This dataset provides general information about each collision and details of all traffic collisions occurring on county and local roadways within Montgomery County,...

  9. General Outside Employment

    Data.gov (United States)

    Montgomery County of Maryland — This dataset contains all outside employment requests held by employees of Montgomery County (excluding uniformed police officer) approved by the Ethics Commission...

  10. County Spending

    Data.gov (United States)

    Montgomery County of Maryland — This dataset includes County spending data for Montgomery County government. It does not include agency spending. Data considered sensitive or confidential and will...

  11. OMB Recommended vs Approved Operating Budget

    Data.gov (United States)

    Montgomery County of Maryland — This dataset includes the Fiscal Year 2015 County Executive Recommended and County Council Approved operating budgets for Montgomery County, for comparison purposes....

  12. Download this PDF file

    African Journals Online (AJOL)

    Sitwala

    2005. Infant feeding practices of mothers of known HIV status in Lusaka,. Zambia. UniversityTeaching Hospital, Lusaka,. Zambia. 17. Pallant, J., 2005. Statistical package for social sciences survival manual: A step by step guide to data analysis using SPSS., 2nd edition, Sydney: Ligare. 18. Preble, E.G. and E.G. Piwoz, 1998.

  13. 77 FR 70410 - Endangered and Threatened Wildlife and Plants; Initiation of Status Review and 5-Year Review of...

    Science.gov (United States)

    2012-11-26

    ...-0095; FXES11130900000-134-FF09E30000] Endangered and Threatened Wildlife and Plants; Initiation of... Linner, Field Supervisor, Colorado Ecological Services Office; mailing address P.O. Box 25486, DFC (MS... SPR (76 FR 76987); and (8) Information regarding contact and interaction among Preble's populations or...

  14. 78 FR 13476 - Modification of the Port Limits of Green Bay, WI

    Science.gov (United States)

    2013-02-28

    ... the townships of Ashwaubenon, Allouez, Preble and Howard and the city of De Pere, all in the State of... port limits in the docket as ``Attachment A: Green Bay (Current).'' CBP proposed to amend the port... limits is included in the docket as ``Attachment B: Green Bay (Proposed).'' Interested parties were given...

  15. Adjunctive minocycline treatment for major depressive disorder: A proof of concept trial.

    Science.gov (United States)

    Dean, Olivia M; Kanchanatawan, Buranee; Ashton, Melanie; Mohebbi, Mohammadreza; Ng, Chee Hong; Maes, Michael; Berk, Lesley; Sughondhabirom, Atapol; Tangwongchai, Sookjaroen; Singh, Ajeet B; McKenzie, Helen; Smith, Deidre J; Malhi, Gin S; Dowling, Nathan; Berk, Michael

    2017-08-01

    Conventional antidepressant treatments result in symptom remission in 30% of those treated for major depressive disorder, raising the need for effective adjunctive therapies. Inflammation has an established role in the pathophysiology of major depressive disorder, and minocycline has been shown to modify the immune-inflammatory processes and also reduce oxidative stress and promote neuronal growth. This double-blind, randomised, placebo-controlled trial examined adjunctive minocycline (200 mg/day, in addition to treatment as usual) for major depressive disorder. This double-blind, randomised, placebo-controlled trial investigated 200 mg/day adjunctive minocycline (in addition to treatment as usual) for major depressive disorder. A total of 71 adults with major depressive disorder ( Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition) were randomised to this 12-week trial. Outcome measures included the Montgomery-Asberg Depression Rating Scale (primary outcome), Clinical Global Impression-Improvement and Clinical Global Impression-Severity, Hamilton Anxiety Rating Scale, Quality of Life Enjoyment and Satisfaction Questionnaire, Social and Occupational Functioning Scale and the Range of Impaired Functioning Tool. The study was registered on the Australian and New Zealand Clinical Trials Register: www.anzctr.org.au , #ACTRN12612000283875. Based on mixed-methods repeated measures analysis of variance at week 12, there was no significant difference in Montgomery-Asberg Depression Rating Scale scores between groups. However, there were significant differences, favouring the minocycline group at week 12 for Clinical Global Impression-Improvement score - effect size (95% confidence interval) = -0.62 [-1.8, -0.3], p = 0.02; Quality of Life Enjoyment and Satisfaction Questionnaire score - effect size (confidence interval) = -0.12 [0.0, 0.2], p minocycline may be a useful adjunct to improve global experience, functioning and quality of life in people with

  16. Variation in the life-history traits of a Schilbid catfish, Clupisoma garua (Hamilton, 1822) in the coastal waters of southern Bangladesh

    Science.gov (United States)

    Siddik, Muhammad Abu Bakar; Chaklader, Md Reaz; Hanif, Md Abu; Nahar, Ashfaqun; Ilham, Ilham; Cole, Anthony; Fotedar, Ravi

    2017-09-01

    For the first time, the present study reports the life-history traits, comprising length-frequency distribution (LFD), sex ratio (SR), length-weight relationships (LWRs), condition factors (CFs), and relative growth ( W R), of Clupisoma garua in the coastal waters of Bangladesh. A total of 150 specimens ranging from 8.60 to 25.20 cm total length (TL) and 4.26 to 128.80 g body weight (BW) were collected using traditional fishing gear from August 2013 to July 2014. The overall sex ratio of males to females in the study did not differ significantly from the expected value of 1:1 (χ2 =0.96, P K A , K F , K R ) and relative growth ( W R ) also did not differ significantly ( P strategies and regulations for the sustainable management of the remaining stocks of this species in the entire coastal region of southern Bangladesh.

  17. Effect of dietary supplemented andrographolide on growth, non-specific immune parameters and resistance against Aeromonas hydrophila in Labeo rohita (Hamilton).

    Science.gov (United States)

    Basha, Kusunur Ahamed; Raman, Ram Prakash; Prasad, Kurcheti Pani; Kumar, Kundan; Nilavan, Ezhil; Kumar, Saurav

    2013-11-01

    The present study evaluated the effect of dietary andrographolide (EC 50%) on growth, non-specific immune parameters and disease resistance against Aeromonas hydrophila infection in Indian major carp, Labeo rohita fingerlings. Fishes were fed with formulated diet containing andrographolide as T0 (0.00%), T1 (0.05%), T2 (0.10%), T3 (0.20%), T4 (0.40%) and T5 (0.80%) for 42 days. Fishes were challenged with A. hydrophila 42 days post feeding and relative percentage survival (RPS) was recorded over 14 days post challenge. Blood and serum samples were collected for nonspecific immune parameters on 14, 28 and 42 days of feeding and growth performance was evaluated at the end of experiment. The results revealed that fishes fed with andrographolide showed significant (p andrographolide were found to be significantly (p andrographolide at the level of 0.10% showed significantly (P andrographolide supplemented diet has a stimulatory effect on non-specific immune parameters along with improved growth performance and increased disease resistance against A. hydrophila infection in L. rohita fingerlings. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Study of the Genetic Diversity of the Ornamental Fish Badis badis (Hamilton-Buchanan, 1822 in the Terai Region of Sub-Himalayan West Bengal, India

    Directory of Open Access Journals (Sweden)

    Tanmay Mukhopadhyay

    2014-01-01

    Full Text Available Dwarf chameleon fish or Badis badis, a lesser known ornamental freshwater fish, has recently been included in the Indian threatened category of fish list. There are insufficient studies with regard to the assessment of genetic background of this ichthyofauna, especially in the western sub-Himalayan region of West Bengal, India, popularly known as the Terai. The present study is the first attempt to investigate the present status of the genetic background of this species in the Mahananda and Balason rivers, major streams of this region. Twenty-one selective RAPD primers generated 53 and 60 polymorphic fragments in the Mahananda and Balason populations, respectively. The proportion of polymorphic loci, Nei’s genetic diversity (H, and Shannon’s index (H′ were 0.4416, 0.1654±0.2023, and 0.2450±0.2907, respectively, in Mahananda river population and were 0.5041, 0.1983±0.2126, and 0.2901±0.3037, respectively, in Balason river population. Inbreeding coefficient and degree of gene differentiation were also calculated. The H and H′ were found to be 0.1601±0.1944 and 0.2363±0.2782, respectively, in overall Mahananda-Balason river system. Our study revealed considerable lack of genetic variation among the individuals of Badis badis. The genetic data obtained from the present study lend support to the view that there is a scope of stock improvement for this ichthyofauna.

  19. Comparative evaluation of fermented and non-fermented de-oiled rice bran with or without exogenous enzymes supplementation in the diet of Labeo rohita (Hamilton, 1822).

    Science.gov (United States)

    Ranjan, Amit; Sahu, Narottam Prasad; Deo, Ashutosh Dharmendra; Kumar, H Sanath; Kumar, Sarvendra; Jain, Kamal Kant

    2018-03-29

    A 60-day feeding trial was conducted to study the effect of exogenous enzymes (xylanase and phytase) supplementation in the non-fermented and fermented de-oiled rice bran (DORB)-based diet of Labeo rohita. Four test diets (T1-DORB-based diet, T2-fermented DORB-based diet, T3-phytase and xylanase supplemented DORB-based diet, and T4-phytase and xylanase supplemented fermented DORB-based diet) were formulated and fed to the respective groups. Test diets T3 and T4 were supplemented with 0.01% xylanase (16,000 U kg -1 ) and 0.01% phytase (500 U kg -1 ) enzymes. One hundred twenty juveniles of L. rohita, with an average weight 5.01 ± 0.02 g, were stocked in 12 uniform size plastic rectangular tanks in triplicate with 10 fishes per tank following a completely randomized design (CRD). Exogenous enzyme supplementation to the T3 group significantly improved the growth performance of L. rohita (p exogenous enzymes. The carcass composition (except CP %), enzyme activities (except amylase activity), globulin, and A/G ratio did not vary significantly (p > 0.05). Based on the results of the present study, it is concluded that exogenous enzyme supplementation significantly increases the growth of fish fed with DORB-based diet.

  20. The Permanent Secretary as Policy-Maker, Shaper, Taker, Sharer, and Resister in Education--Reflections on Sir James Hamilton as a Centralising Outsider

    Science.gov (United States)

    Ribbins, Peter; Sherratt, Brian

    2013-01-01

    Given that elevation to permanent secretary is widely recognised as the apotheosis of a career in the Whitehall bureaucracy, it is remarkable that so few have been the subject of sustained biographical research and that this key role remains largely un-theorised. As such, this paper reports on aspects of a longitudinal study which set out to…

  1. "Kui Eesti ütleb gaasitorule ei, võib ka Rootsi öelda ei" / Carl B. Hamilton ; interv. Argo Ideon

    Index Scriptorium Estoniae

    Hamilton, Carl B.

    2007-01-01

    Nord Stream on avaldanud soovi gaasijuhtme teenindusplatvormi rajamiseks Gotlandi juurde. Parlamendiliikme hinnangul peaks Rootsi valitsus ütlema ei nii teenindusplatvormile kui ka gaasitorule. Gaasijuhe on tema sõnul Venemaa projekt

  2. Effects of the wood extractive betulinol and 17beta-oestradiol on reproduction in zebrafish, Danio rerio (Hamilton)--complications due to a bacterial infection.

    Science.gov (United States)

    Christianson-Heiska, I; Wahteristo, P; Kastilan, E-L; Bergelin, E; Bylund, G; Isomaa, B

    2004-05-01

    Zebrafish were exposed to the wood extractive betulinol (5 microg L(-1)) and to 17beta-oestradiol (E2, 0.27 microg L(-1)) for 8 weeks in an attempt to study the possible endocrine-disrupting activity of betulinol. Females exposed to betulinol showed increased spawning intensity, while males exposed to betulinol and E2 had increased incidences of structural alterations in the testes. However, histological examination of the fish revealed that they were infected by acid-fast bacteria suspected to be Mycobacterium sp. despite a careful examination of their health state prior to the onset of the experiment. Fish exposed to betulinol and E2 showed more serious consequences of the bacterial infection than control fish indicating that the test chemicals had weakened the immune defence of the fish. When the exposure was repeated with healthy fish, an increase in the proportion of spermatogonia was seen in the testes of betulinol-treated males. A similar alteration, although not statistically significant, was also seen in the first experiment. However, no increase in the incidences of structural alterations in the testes was seen in betulinol- and E2-treated fish in the second experiment. Our study indicates that betulinol might have an endocrine-disrupting effect in zebrafish, but the increase in incidences of structural alterations in the testes might have been caused by a synergistic action between the test compounds and the bacterial infection. Our study stresses the importance of carefully checking the health of experimental fish, not only prior to the onset of an experiment but also upon termination of the experiment, in order to avoid misinterpretation of the results.

  3. Identification of reproduction-related genes and SSR-markers through expressed sequence tags analysis of a monsoon breeding carp rohu, Labeo rohita (Hamilton).

    Science.gov (United States)

    Sahu, Dinesh K; Panda, Soumya P; Panda, Sujata; Das, Paramananda; Meher, Prem K; Hazra, Rupenangshu K; Peatman, Eric; Liu, Zhanjiang J; Eknath, Ambekar E; Nandi, Samiran

    2013-07-15

    Labeo rohita (Ham.) also called rohu is the most important freshwater aquaculture species on the Indian sub continent. Monsoon dependent breeding restricts its seed production beyond season indicating a strong genetic control about which very limited information is available. Additionally, few genomic resources are publicly available for this species. Here we sought to identify reproduction-relevant genes from normalized cDNA libraries of the brain-pituitary-gonad-liver (BPGL-axis) tissues of adult L. rohita collected during post preparatory phase. 6161 random clones sequenced (Sanger-based) from these libraries produced 4642 (75.34%) high-quality sequences. They were assembled into 3631 (78.22%) unique sequences composed of 709 contigs and 2922 singletons. A total of 182 unique sequences were found to be associated with reproduction-related genes, mainly under the GO term categories of reproduction, neuro-peptide hormone activity, hormone and receptor binding, receptor activity, signal transduction, embryonic development, cell-cell signaling, cell death and anti-apoptosis process. Several important reproduction-related genes reported here for the first time in L. rohita are zona pellucida sperm-binding protein 3, aquaporin-12, spermine oxidase, sperm associated antigen 7, testis expressed 261, progesterone receptor membrane component, Neuropeptide Y and Pro-opiomelanocortin. Quantitative RT-PCR-based analyses of 8 known and 8 unknown transcripts during preparatory and post-spawning phase showed increased expression level of most of the transcripts during preparatory phase (except Neuropeptide Y) in comparison to post-spawning phase indicating possible roles in initiation of gonad maturation. Expression of unknown transcripts was also found in prolific breeder common carp and tilapia, but levels of expression were much higher in seasonal breeder rohu. 3631 unique sequences contained 236 (6.49%) putative microsatellites with the AG (28.16%) repeat as the most frequent motif. Twenty loci showed polymorphism in 36 unrelated individuals with allele frequency ranging from 2 to 7 per locus. The observed heterozygosity ranged from 0.096 to 0.774 whereas the expected heterozygosity ranged from 0.109 to 0.801. Identification of 182 important reproduction-related genes and expression pattern of 16 transcripts in preparatory and post-spawning phase along with 20 polymorphic EST-SSRs should be highly useful for the future reproductive molecular studies and selection program in Labeo rohita. Copyright © 2013 Elsevier B.V. All rights reserved.

  4. Light regimes differentially affect baseline transcript abundance of stress-axis and (neurodevelopment-related genes in zebrafish (Danio rerio, Hamilton 1822 AB and TL larvae

    Directory of Open Access Journals (Sweden)

    Ruud van den Bos

    2017-11-01

    Full Text Available Many strains of zebrafish (Danio rerio are readily available. Earlier we observed differences between AB and Tupfel long-fin (TL larvae regarding baseline hypothalamus-pituitary-interrenal (HPI axis activity and (neurodevelopment. Light regimes, i.e. 14 h light:10 h dark and 24 h continuous dark or light, affect hatching rate and larval growth. Here, we assessed baseline transcript abundance of HPI-axis-related genes and (neurodevelopment-related genes of AB and TL larvae (5 days post fertilisation using these light regimes. A principal component analysis revealed that in AB larvae the baseline expression of HPI-axis-related genes was higher the more hours of light, while the expression of (neurodevelopment-related genes was higher under 14 h light:10 h dark than under both continuous light or dark. In TL larvae, a complex pattern emerged regarding baseline expression of HPI-axis-related and (neurodevelopment-related genes. These data extend data of earlier studies by showing that light regimes affect gene-expression in larvae, and more importantly so, strengthen the notion of differences between larvae of the AB and TL strain. The latter finding adds to the growing database of phenotypical differences between zebrafish of the AB and TL strain.

  5. Effects of nickel chloride and oxygen depletion on behaviour and vitality of zebrafish (Danio rerio, Hamilton, 1822) (Pisces, Cypriniformes) embryos and larvae

    International Nuclear Information System (INIS)

    Kienle, Cornelia; Koehler, H.-R.; Filser, Juliane; Gerhardt, Almut

    2008-01-01

    We examined acute (2 h exposure of 5-day-old larvae) and subchronic (exposure from fertilization up to an age of 11 days) effects of NiCl 2 .6H 2 O on embryos and larvae of zebrafish (Danio rerio), both alone and in combination with oxygen depletion. The following endpoints were recorded: acute exposure: locomotory activity and survival; subchronic exposure: hatching rate, deformations, locomotory activity (at 5, 8 and 11 days) and mortality. In acute exposures nickel chloride (7.5-15 mg Ni/L) caused decreasing locomotory activity. Oxygen depletion (≤2.45 ± 0.16 mg O 2 /L) also resulted in significantly reduced locomotory activity. In the subchronic test, exposure to ≥10 mg Ni/L resulted in delayed hatching at an age of 96 h, in decreased locomotory activity at an age of 5 days, and increased mortality at an age of 11 days (LC 20 = 9.5 mg Ni/L). The observed LOEC for locomotory activity (7.5 mg Ni/L) is in the range of environmentally relevant concentrations. Since locomotory activity was already affected by acute exposure, this parameter is recommended to supplement commonly recorded endpoints of toxicity. - Increasing concentrations of nickel chloride and decreasing concentrations of oxygen lead to reduced vitality and locomotory activity in Danio rerio embryos and larvae

  6. Some observations on the morphometry and biology of Psettodes erumei (Bloch) and Pseudorhombus arsius (Hamilton-Buchanan) from the Goa region

    Digital Repository Service at National Institute of Oceanography (India)

    Menezes, M.R.

    . erumei and the number of dorsal fin rays in P. arsius were relatively stable characters. Statistical interpretation of metric data indicated that there is direct relationship between the head length, depth of the body and total length...

  7. Genotoxic effects and gene expression in Danio rerio (Hamilton 1822) (Cypriniformes: Cyprinidae) exposed to mining-impacted tributaries in Manizales, Colombia.

    Science.gov (United States)

    Ossa-López, Paula A; Castaño-Villa, Gabriel J; Rivera-Páez, Fredy A

    2017-09-25

    The zebrafish (Danio rerio) is one of the most studied aquatic organisms for water biomonitoring, due to its sensitivity to environmental degradation and resistance to toxic substances. This study determined the presence of micronuclei and nuclear abnormalities in peripheral blood erythrocytes, and assessed the gene expression of caspase-3 (CASP-3) and metallothionein 1 (MT-1) in the gills and liver of D. rerio. The study fish (n = 45) were exposed to water collected from two stations with mining impact (E2 and E3) and a reference station without evident mining contamination (E1), all located in La Elvira stream (Manizales-Colombia). In addition, a positive control (PC) with HgCl 2 (50 μg/L) and negative control (NC) with tap water were included. The fish from the PC and E2 and E3 treatments displayed genotoxic effects and changes in gene expression, with significant differences in micronuclei formation and the presence of blebbed nuclei. The cytochrome oxidase subunit I (COI) gene was used as reference and proved to be stable compared to the β-actin and 28S ribosomal RNA (28S) genes. In gills, CASP-3 expression was higher in the PC, and MT-1 expression was higher in the PC and E3 treatment. In liver, CASP-3 was expressed in the E2 treatment, and MT-1 expression was low. These results show that the genotoxic effects and differential gene expression observed in fish exposed to water from La Elvira stream could also be affecting the organisms present in this habitat.

  8. Finding of No Significant Impact: Proposed Bank Stabilization Tennessee River River Mile 466.2 - 466.5, Hamilton County, Tennessee

    Science.gov (United States)

    2013-05-02

    Bank erosion is endangering approximately 1,100 feet of a 42-inch concrete gravity sanitary main, two manholes, and a 30-inch iron sanitary sewer...stabilizing the bank. Kingfisher nests are excavated burrows with bare soil along stream banks (USACE, 2009). “Banks with a high content of clay , gravel, or...34’ g -- - -- - - ---- --- -------- 1 LEGEND ESTIMATED 42’’ GRAVITY SEWER LINE ESTIMATED 30’’ FORCE MAIN ® SANITARY SEWER MANHOLE • AUTO

  9. Population growth, trophic level, and reproductive biology of two congeneric archer fishes (Toxotes chatareus, Hamilton 1822 and Toxotes jaculatrix, Pallas 1767) inhabiting Malaysian coastal waters.

    Science.gov (United States)

    Simon, K D; Bakar, Y; Samat, A; Zaidi, C C; Aziz, A; Mazlan, A G

    2009-12-01

    Population growth, trophic level, and some aspects of reproductive biology of two congeneric archer fish species, Toxotes chatareus and Toxotes jaculatrix, collected from Johor coastal waters, Malaysia, were studied. Growth pattern by length-weight relationship (W=aL(b)) for the sexes differed, and exhibited positive allometric growth (male, female and combined sexes of T. chatareus; female and combined sexes of T. jaculatrix) and isometric growth (male samples of T. jaculatrix only). Trophic levels of both species were analyzed based on 128 specimens. The results show that, in both species, crustaceans and insects were the most abundant prey items, and among crustaceans the red clawed crab Sesarma bidens and Formicidae family insects were the most represented taxa. The estimated mean trophic levels for T. chatareus and T. jaculatrix were 3.422+/-0.009 and 3.420+/-0.020, respectively, indicating that they are largely carnivores. Fecundity of T. chatareus ranged from 38 354 to 147 185 eggs for females with total length ranging from 14.5 to 22.5 cm and total body weight from 48.7 to 270.2 g, and T. jaculatrix 25 251 to 150 456 eggs for females with total length ranging from 12.2 to 23.0 cm and total body weight from 25.7 to 275.0 g. Differences in values of gonadosomatic and hepatosomatic indexes calculated for both species in this study may have resulted from uneven sample size ranges.

  10. Prime Contract Awards Alphabetically by Contractor, by State or Country, and Place. Part 10 (Germer Equipment Co-Hamilton Hilton National Wembley)

    Science.gov (United States)

    1990-01-01

    m’ 1) 00 00 00 m 1-r 0" ’m2 II ON ’r- - .- - C LOOcOaOC C> CC’m CI- t t mI ’U ’r 0(1 )0 - LN U L6 L, -4 0)C𔃼C𔃼( MPC4 C-’UN L 400 01-41 m2 T "O ’U 0

  11. Fewer study participants needed to demonstrate superior antidepressant efficacy when using the Hamilton melancholia subscale (HAM-D6) as outcome measure

    DEFF Research Database (Denmark)

    Østergaard, Søren Dinesen; Bech, Per; Miskowiak, Kamilla Woznica

    2016-01-01

    participants per group would be required to detect a statistically significant difference between EPO and placebo when using the HAM-D6 as outcome measure, whereas the required group size for HAM-D17 would be 146 participants. Limitations The EPO RCT was not originally designed to investigate the research...... placebo-controlled trial (RCT) testing the effect of erythropoietin (EPO) as augmentation therapy in patients with treatment-resistant depression.  Methods We assessed the scalability (Mokken analysis of unidimensionality), responsiveness (item responsiveness analysis) and ability to show drug......-placebo separation (estimation of sample size needed to detect statistically significant difference between EPO and placebo) of the HAM-D6 and the HAM-D17.  Results The HAM-D6 demonstrated higher scalability, higher responsiveness, and better drug-placebo separation compared to the HAM-D17. As a consequence, only 39...

  12. De novo development and characterization of polymorphic microsatellite markers in a schilbid catfish, Silonia silondia (Hamilton, 1822) and their validation for population genetic studies.

    Science.gov (United States)

    Mandal, Sangeeta; Jena, J K; Singh, Rajeev K; Mohindra, Vindhya; Lakra, W S; Deshmukhe, Geetanjali; Pathak, Abhinav; Lal, Kuldeep K

    2016-02-01

    The stock characterization of wild populations of Silonia silondia is important for its scientific management. At present, the information on genetic parameters of S. silondia is very limited. The species-specific microsatellite markers were developed in current study. The validated markers were used to genotype individuals from four distant rivers. To develop de novo microsatellite loci, an enriched genomic library was constructed for S. silondia using affinity-capture approach. The markers were validated for utility in population genetics. A total number of 76 individuals from four natural riverine populations were used to generate data for population analysis. The screening of isolated repeat sequences yielded eleven novel polymorphic microsatellite loci. The microsatellite loci exhibited high level of polymorphism, with 6-24 alleles per locus and the PIC value ranged from 0.604 to 0.927. The observed (Ho) and expected (He) heterozygosities ranged from 0.081 to 0.84 and 0.66 to 0.938, respectively. The AMOVA analysis indicated significant genetic differentiation among riverine populations (overall FST = 0.075; P < 0.0001) with maximum variation (92.5%) within populations. Cross-priming assessment revealed successful amplification (35-38 %) of heterologous loci in four related species viz. Clupisoma garua, C. taakree, Ailia coila and Eutropiichthys vacha. The results demonstrated that these de novo polymorphic microsatellite loci are promising for population genetic variation and diversity studies in S. silondia. Cross-priming results indicated that these primers can help to get polymorphic microsatellite loci in the related catfish species of family Schilbidae.

  13. Good Teachers, Scholarly Teachers and Teachers Engaged in Scholarship of Teaching and Learning: A Case Study from McMaster University, Hamilton, Canada

    Science.gov (United States)

    Vajoczki, Susan; Savage, Philip; Martin, Lynn; Borin, Paola; Kustra, Erika D. H.

    2011-01-01

    This paper defines and operationalizes definitions of good teaching, scholarly teaching and the scholarship of teaching and learning in order to measure characteristics of these definitions amongst undergraduate instructors at McMaster University. A total of 2496 instructors, including all part-time instructors, were surveyed in 2007. A total of…

  14. Effect of exposure to sublethal concentrations of sodium cyanide on the carbohydrate metabolism of the Indian Major Carp Labeo rohita (Hamilton, 1822

    Directory of Open Access Journals (Sweden)

    Praveen N. Dube

    2013-07-01

    Full Text Available Experiments were designed to study in-vivo effects of sodium cyanide on biochemical endpoints in the freshwater fish Labeo rohita. Fish were exposed to two sublethal concentrations (0.106 and 0.064mg/L for a period of 15 days. Levels of glycogen, pyruvate, lactate and the enzymatic activities of lactate dehydrogenase (LDH, succinate dehydrogenase (SDH, glucose-6-phosphate dehydrogenase (G6PDH, phosphorylase, alkaline phosphatase (ALP, acid phosphatase (AcP were assessed in different tissues (liver, muscle and gills. Result indicated a steady decrease in glycogen, pyruvate, SDH, ALP and AcP activity with a concomitant increase in the lactate, phosphorylase, LDH and G6PD activity in all selected tissues. The alterations in all the above biochemical parameters were significantly (p<0.05 time and dose dependent. In all the above parameters, liver pointing out the intensity of cyanide intoxication compare to muscle and gills. Study revealed change in the metabolic energy by means of altered metabolic profile of the fish. Further, these observations indicated that even sublethal concentrations of sodium cyanide might not be fully devoid of deleterious influence on metabolism in L. rohita.

  15. Transcultural Adaptation of GRID Hamilton Rating Scale For Depression (GRID-HAMD) to Brazilian Portuguese and Evaluation of the Impact of Training Upon Inter-Rater Reliability.

    Science.gov (United States)

    Henrique-Araújo, Ricardo; Osório, Flávia L; Gonçalves Ribeiro, Mônica; Soares Monteiro, Ivandro; Williams, Janet B W; Kalali, Amir; Alexandre Crippa, José; Oliveira, Irismar Reis De

    2014-07-01

    GRID-HAMD is a semi-structured interview guide developed to overcome flaws in HAM-D, and has been incorporated into an increasing number of studies. Carry out the transcultural adaptation of GRID-HAMD into the Brazilian Portuguese language, evaluate the inter-rater reliability of this instrument and the training impact upon this measure, and verify the raters' opinions of said instrument. The transcultural adaptation was conducted by appropriate methodology. The measurement of inter-rater reliability was done by way of videos that were evaluated by 85 professionals before and after training for the use of this instrument. The intraclass correlation coefficient (ICC) remained between 0.76 and 0.90 for GRID-HAMD-21 and between 0.72 and 0.91 for GRID-HAMD-17. The training did not have an impact on the ICC, except for a few groups of participants with a lower level of experience. Most of the participants showed high acceptance of GRID-HAMD, when compared to other versions of HAM-D. The scale presented adequate inter-rater reliability even before training began. Training did not have an impact on this measure, except for a few groups with less experience. GRID-HAMD received favorable opinions from most of the participants.

  16. Simulation of aquifer tests and ground-water flowpaths at the local scale in fractured shales and sandstones of the Brunswick Group and Lockatong Formation, Lansdale, Montgomery County, Pennsylvania

    Science.gov (United States)

    Goode, Daniel J.; Senior, Lisa A.

    2000-01-01

    The U.S. Geological Survey, as part of technical assistance to the U.S. Environmental Protection Agency, has constructed and calibrated models of local-scale ground-water flow in and near Lansdale, Pa., where numerous sources of industrial contamination have been consolidated into the North Penn Area 6 Superfund Site. The local-scale models incorporate hydrogeologic structure of northwest-dipping beds with uniform hydraulic properties identified in previous studies. Computations associated with mapping the dipping-bed structure into the three-dimensional model grid are handled by a preprocessor using a programmed geographic information system (GIS). Hydraulic properties are identified by calibration of the models using measured water levels during pumping and recovery from aquifer tests at three sites. Reduced flow across low-permeability beds is explicitly simulated. The dipping high-permeability beds are extensive in the strike direction but are of limited extent in the dip direction. This model structure yields ground-water-flow patterns characteristic of anisotropic aquifers; preferred flow is in the strike direction. The transmissivities of high-permeability beds in the local-scale models range from 142 to 1,900 ft2/d (feet squared per day) (13 to 177 m2/d). The hydraulic conductivities of low-permeability parts of the aquifer range from 9.6 x 10-4 to 0.26 ft/d (feet per day) (2.9 x 10-4 to 0.079 m/d). Storage coefficients and specific storage are very low, indicating the confined nature of the aquifer system. The calibrated models are used to simulate contributing areas of wells under alternative, hypothetical ground-water-management practices. Predictive contributing areas indicate the general characteristics of ground-water flow towards wells in the Lansdale area. Recharge to wells in Lansdale generally comes from infiltration near the well and over an area that extends upgradient from the well. The contributing areas for two wells pumping at 10 gal/min (gallons per minute) extend about 1,500 ft (feet) upgradient from the wells. The contributing area is more complex at ground-water divides and can extend in more than one direction to capture recharge from more than 3,300 ft away, for pumping at a rate of 30 gal/min. Locally, all recharge in the area of the pumping well is not captured; recharge in the downgradient direction about 150 ft from the pumping well will flow to other discharge locations.

  17. National Research Council, 2003, Cities Transformed. Demographic Change and its Implications in the Developing World. Panel on Urban Population Dynamics, M. Montgomery, R. Stren, B. Cohen. and H. Reed (eds.), Committee on Population, Division of

    OpenAIRE

    Thomas, Isabelle

    2004-01-01

    Telle est exactement la manière officielle de citer l’ouvrage (p. ii).  Il s’agit en fait d’un support papier très court (un résumé de 6 pages accompagné d’une table de matières et de quelques avant-propos) accompagné d’un CD-rom sur lequel se trouve le livre.  L’ouvrage est composé de 10 chapitres et d’une série d’annexes, chaque chapitre constituant un fichier en format pdf, à consulter indépendamment, sans aucun lien  hypertexte.  Cette forme surprend un peu : pourquoi ne pas avoir envisag...

  18. Chronotoxicity of contaminants (etanol and hezvy metales) in a freshwater teleost Dario rerio (Hamilton, 1882) and marine amphipods Gammarus aequicauda (Martynov, 1931) and Gammarus chevreuxi (Sexton, 1913) = Cronotixicidad de contaminantes (etanol y metales pesados) en el teleósteo de agua dulce Dario rerio (Hamilton, 1822) y los antípodos marinos, Gammarus aequicauda (Martynov, 1931) y Gammarus chevreuxi (Sexton, 1913)

    OpenAIRE

    Bello Marín, Carolina

    2015-01-01

    Esta tesis tiene como objetivo investigar los efectos del etanol y metales pesados (cadmio y mercurio) en los patrones diarios de dos especies acuáticas clave: pez cebra (Darío rerio) y anfípodo gammarus (G. aequicauda y G. chevreuxi). La investigación se realizó en dos niveles organizativos: comportamental y molecular. Con este fin, hemos establecido cuatro objetivos específicos: 1. Investigar los efectos al etanol en el pez cebra en función en su ritmo circadiano. 2. Determinar la exi...

  19. An analysis of correlations among four outcome scales employed in clinical trials of patients with major depressive disorder

    Directory of Open Access Journals (Sweden)

    Ahmed Saeeduddin

    2009-01-01

    Full Text Available Abstract Background The 17-item Hamilton Depression Rating Scale (HAM-D17 remains the 'gold standard' for measuring treatment outcomes in clinical trials of depressed patients. The Montgomery Ǻsberg Depression Rating Scale (MADRS, Clinical Global Impressions-Severity (CGI-S and -Improvement (CGI-I scales are also widely used. Objective This analysis of data from 22 double-blind, placebo-controlled clinical studies of venlafaxine in adult patients with major depressive disorder was aimed at assessing correlations among these 4 scales. Methods Changes from baseline for MADRS, HAM-D17 and CGI-S, and end point CGI-I scores and response (≥50% decrease from baseline HAM-D17 or MADRS, or CGI-S or CGI-I score ≤2 were analysed. Pearson correlation coefficients were calculated for all pairs of the four scales (HAM-D17/MADRS, HAM-D17/CGI-S, HAM-D17/CGI-I, MADRS/CGI-S, MADRS/CGI-I, CGI-S/CGI-I at different time points. Effect sizes were calculated using the Cohen d. Results Correlations were significant at all time points (p 17 or CGI-S for continuous measures and response. Conclusion Although MADRS and CGI-I were more sensitive to treatment effects, HAM-D17, MADRS, CGI-S and CGI-I scores present a consistent picture of response to venlafaxine treatment.

  20. Pindolol augmentation in treatment-resistant obsessive compulsive disorder: a double-blind placebo controlled trial.

    Science.gov (United States)

    Dannon, P N; Sasson, Y; Hirschmann, S; Iancu, I; Grunhaus, L J; Zohar, J

    2000-05-01

    To evaluate the efficacy of pindolol augmentation in treatment-resistant obsessive compulsive disorder (OCD) patients who were unsuccessfully treated with serotonin reuptake inhibitors. Fourteen treatment-resistant OCD patients were treated with paroxetine for 17.4+/-2.1 weeks up to 60 mg/d after they failed at least two other serotonin reuptake inhibitor trials. The patients, who did not respond to open-label paroxetine treatment, were assigned to a double-blind, placebo-controlled pindolol (2.5 mgx3/d) augmentation. All the subjects were evaluated biweekly for a six-week period with the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), Hamilton Anxiety Scale (HAM-Anx), and Montgomery Asberg Depression Rating Scale (MADRS). Data was analyzed by paired t-test, and ANOVA with repeated measures. Pindolol augmentation to paroxetine (n=8) as compared to placebo augmentation (n=6), was associated with a significant (P<0.01) improvement in Y-BOCS as measured by paired t-test after the fourth week of the treatment and by ANOVA with repeated measures (df: 4.9, f: 3,3, P<0.006). Although no significant differences were found between placebo and pindolol groups on HAM-Anx and MADRS, a trend for improvement in the pindolol group was noted. The results of our study demonstrated that pindolol may augment the therapeutic effect of paroxetine in treatment-resistant OCD patients.

  1. Peculiar alexithymic traits in burning mouth syndrome: case-control study.

    Science.gov (United States)

    Marino, Roberto; Picci, Rocco Luigi; Ferro, Giovanni; Carezana, Claudio; Gandolfo, Sergio; Pentenero, Monica

    2015-11-01

    The present case-control study aims to assess the occurrence of alexithymic traits in burning mouth syndrome (BMS) subjects and to correlate alexithymic traits to anxious and depressive traits in BMS subjects. Prospectively enrolled BMS and control subjects were administered the 20-item Toronto Alexithymia Scale (TAS-20). Anxiety and depressive traits were assessed using the Hamilton Anxiety Rating Scale and the Montgomery and Asberg Depression Rating Scale. Occurrence of alexithymic traits was compared between BMS and control subjects. Correlation tests were used to measure the importance of alexithymic traits related to demographic characteristics, pain intensity (VAS score), and to the other psychometric scores. Fifty-eight BMS subjects (46 females and 12 males) had a mean TAS-20 score significantly higher when compared to controls (p < 0.001; r = 0.72), corresponding to an occurrence rate of alexithymic traits of 79.3 versus 6.9%. Alexithymic traits in BMS subjects were just related to depressive traits (p = 0.02; ρ = 0.31). The high occurrence of alexithymia in BMS is an adjunctive issue in favor of its multifactorial pathogenesis, with a not negligible role for somatization. Clinicians should be aware of the high occurrence of alexithymic traits among BMS subjects as such traits may affect the doctor-patient relationship.

  2. Parallel-group placebo-controlled trial of testosterone gel in men with major depressive disorder displaying an incomplete response to standard antidepressant treatment.

    Science.gov (United States)

    Pope, Harrison G; Amiaz, Revital; Brennan, Brian P; Orr, Guy; Weiser, Mark; Kelly, John F; Kanayama, Gen; Siegel, Arthur; Hudson, James I; Seidman, Stuart N

    2010-04-01

    Exogenous testosterone therapy has psychotropic effects and has been proposed as an antidepressant augmentation strategy for depressed men. We sought to assess the antidepressant effects of testosterone augmentation of a serotonergic antidepressant in depressed, hypogonadal men. For this study, we recruited 100 medically healthy adult men with major depressive disorder showing partial response or no response to an adequate serotonergic antidepressant trial during the current episode and a screening total testosterone level of 350 ng/dL or lower. We randomized these men to receive testosterone gel or placebo gel in addition to their existing antidepressant regimen. The primary outcome measure was the Hamilton Depression Rating Scale (HDRS) score. Secondary measures included the Montgomery-Asberg Depression Rating Scale, the Clinical Global Impression Scale, and the Quality of Life Scale. Our primary analysis, using a mixed effects linear regression model to compare rate of change of scores between groups on the outcome measures, failed to show a significant difference between groups (mean [95% confidence interval] 6-week change in HDRS for testosterone vs placebo, -0.4 [-2.6 to 1.8]). However, in one exploratory analysis of treatment responders, we found a possible trend in favor of testosterone on the HDRS. Our findings, combined with the conflicting data from earlier smaller studies, suggest that testosterone is not generally effective for depressed men. The possibility remains that testosterone might benefit a particular subgroup of depressed men, but if so, the characteristics of this subgroup would still need to be established.

  3. Interest of targeting either cortical area Brodmann 9 or 46 in rTMS treatment for depression: a preliminary randomized study.

    Science.gov (United States)

    Trojak, Benoit; Meille, Vincent; Jonval, Lysiane; Schuffenecker, Nicolas; Haffen, Emmanuel; Schwan, Raymund; Bonin, Bernard; Chauvet-Gelinier, Jean-Christophe

    2014-12-01

    To assess the interest of specifically targeting Brodmann Areas (BA) 9 or 46 for rTMS treatment of depression. Patients with Treatment-Resistant Depression were randomly assigned to two treatment groups to receive either rTMS on BA 9 or on BA 46. Each patient underwent 10 sessions of 1Hz-rTMS for 2weeks. The Hamilton and Montgomery-Asberg Depression Rating Scales (HDRS, MADRS) were used under blind conditions to assess the therapeutic response (50% improvement). A Wilcoxon signed-rank test was used to compare the depression rating scales scores obtained before and after the 10 rTMS sessions for each of the two groups. The therapeutic results in the two groups were compared using the Mann-Whitney-Wilcoxon test. We also reported the effect sizes using Hedges's g. Fifteen patients were included. Stimulation of both BA 9 (n=7) and BA 46 (n=8) led to similar therapeutic responses in the two groups (with moderate effect size), such as the mean decrease in HDRS (BA 9: p=0.015; BA 46: p=0.010) and MADRS (BA 9: p=0.042; BA 46: p=0.038) scores. Our results do not come out in favor of one or the other BA. Stimulation of BA 9 and BA 46 appears to be equally effective in the treatment of depression. Copyright © 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  4. Effect of desvenlafaxine 50 mg and 100 mg on energy and lassitude in patients with major depressive disorder: A pooled analysis.

    Science.gov (United States)

    Lam, Raymond W; Wajsbrot, Dalia B; Meier, Ellen; Pappadopulos, Elizabeth; Mackell, Joan A; Boucher, Matthieu

    2017-09-01

    Nine randomized, double-blind, placebo-controlled studies of major depressive disorder were pooled to evaluate the effects of desvenlafaxine 50- and 100-mg/d on energy and lassitude in adults with major depressive disorder ( n=4279). Changes from baseline to endpoint in 17-item Hamilton Rating Scale for Depression (HAM-D 17 ) Work and Activities, Retardation, and Somatic Symptoms General items, HAM-D 17 psychomotor retardation factor, and Montgomery-Åsberg Depression Rating Scale Lassitude item were analyzed with a mixed model for repeated measures analysis of variance. Associations between residual energy measures and functional impairment, based on the Sheehan Disability Scale, were modeled using stepwise multiple linear regression. Improvement from baseline was significantly greater for both desvenlafaxine doses versus placebo on all energy symptom outcomes at week 8 (all p⩽0.005). Both early improvement in HAM-D 17 psychomotor retardation at week 2 and residual energy symptoms at week 8 were associated with Sheehan Disability Scale total score at week 8 (all p⩽0.001). Among Sheehan Disability Scale remitters and responders, the HAM-D 17 psychomotor retardation score at week 8 was significantly lower with desvenlafaxine (both doses) than placebo. Desvenlafaxine 50 and 100 mg/d significantly improved energy and lassitude symptoms in patients with major depressive disorder. Both early improvement in energy and fewer residual energy symptoms were associated with functional improvement.

  5. Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report.

    Science.gov (United States)

    Osório, Flávia de L; Sanches, Rafael F; Macedo, Ligia R; Santos, Rafael G dos; Maia-de-Oliveira, João P; Wichert-Ana, Lauro; Araujo, Draulio B de; Riba, Jordi; Crippa, José A; Hallak, Jaime E

    2015-01-01

    Ayahuasca (AYA), a natural psychedelic brew prepared from Amazonian plants and rich in dimethyltryptamine (DMT) and harmine, causes effects of subjective well-being and may therefore have antidepressant actions. This study sought to evaluate the effects of a single dose of AYA in six volunteers with a current depressive episode. Open-label trial conducted in an inpatient psychiatric unit. Statistically significant reductions of up to 82% in depressive scores were observed between baseline and 1, 7, and 21 days after AYA administration, as measured on the Hamilton Rating Scale for Depression (HAM-D), the Montgomery-Åsberg Depression Rating Scale (MADRS), and the Anxious-Depression subscale of the Brief Psychiatric Rating Scale (BPRS). AYA administration resulted in nonsignificant changes in Young Mania Rating Scale (YMRS) scores and in the thinking disorder subscale of the BPRS, suggesting that AYA does not induce episodes of mania and/or hypomania in patients with mood disorders and that modifications in thought content, which could indicate psychedelic effects, are not essential for mood improvement. These results suggest that AYA has fast-acting anxiolytic and antidepressant effects in patients with a depressive disorder.

  6. Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report

    Directory of Open Access Journals (Sweden)

    Flávia de L. Osório

    2015-03-01

    Full Text Available Objectives: Ayahuasca (AYA, a natural psychedelic brew prepared from Amazonian plants and rich in dimethyltryptamine (DMT and harmine, causes effects of subjective well-being and may therefore have antidepressant actions. This study sought to evaluate the effects of a single dose of AYA in six volunteers with a current depressive episode. Methods: Open-label trial conducted in an inpatient psychiatric unit. Results: Statistically significant reductions of up to 82% in depressive scores were observed between baseline and 1, 7, and 21 days after AYA administration, as measured on the Hamilton Rating Scale for Depression (HAM-D, the Montgomery-Åsberg Depression Rating Scale (MADRS, and the Anxious-Depression subscale of the Brief Psychiatric Rating Scale (BPRS. AYA administration resulted in nonsignificant changes in Young Mania Rating Scale (YMRS scores and in the thinking disorder subscale of the BPRS, suggesting that AYA does not induce episodes of mania and/or hypomania in patients with mood disorders and that modifications in thought content, which could indicate psychedelic effects, are not essential for mood improvement. Conclusions: These results suggest that AYA has fast-acting anxiolytic and antidepressant effects in patients with a depressive disorder.

  7. A new chronobiological approach to discriminate between acute and chronic depression using peripheral temperature, rest-activity, and light exposure parameters.

    Science.gov (United States)

    Ávila Moraes, Cláudia; Cambras, Trinitat; Diez-Noguera, Antoni; Schimitt, Regina; Dantas, Giovana; Levandovski, Rosa; Hidalgo, Maria Paz

    2013-03-09

    Circadian theories for major depressive disorder have suggested that the rhythm of the circadian pacemaker is misaligned. Stable phase relationships between internal rhythms, such as temperature and rest/activity, and the external day-night cycle, are considered to be crucial for adapting to life in the external environmental. Therefore, the relationship and possible alterations among (i) light exposure, (ii) activity rhythm, and (iii) temperature rhythm could be important factors in clinical depression. This study aimed to investigate the rhythmic alterations in depression and evaluate the ability of chronobiological parameters to discriminate between healthy subjects and depressed patients. Thirty female subjects, including healthy subjects, depressed patients in the first episode, and major recurrent depression patients. Symptoms were assessed using Hamilton Depression Scale, Beck Depression Inventory and Montgomery-Äsberg Scale. Motor activity, temperature, and light values were determined for 7 days by actigraph, and circadian rhythms were calculated. Depressed groups showed a lower amplitude in the circadian rhythm of activity and light exposure, but a higher amplitude in the rhythm of peripheral temperature. The correlation between temperature and activity values was different in the day and night among the control and depressed groups. For the same level of activity, depressed patients had lowest temperature values during the day. The amplitudes of temperature and activity were the highest discriminant parameters. These results indicate that the study of rhythms is useful for diagnosis and therapy for depressive mood disorders.

  8. Assessment of mood: guides for clinicians.

    Science.gov (United States)

    Furukawa, Toshi A

    2010-06-01

    This article is one of the series of review articles aiming to present a convenient guideline for practicing clinicians in their selection of scales for clinical and research purposes. This article focuses on assessment scales for mood (depression, mania). After reviewing the basic principles of clinical psychometrics, we present a selective review of representative scales measuring depressed or manic mood. We reviewed and reported on reliability, validity, interpretability, and feasibility of the following rating scales: Patient Health Questionnaire-9 (PHQ-9), K6, Beck Depression Inventory II (BDI-II), and Quick Inventory of Depressive Symptomatology Self-Report (QIDS-SR) as self-report scales for depressed mood; Hamilton Rating Scale for Depression (HAM-D) and Montgomery-Asberg Depression Rating Scale (MADRS) as clinician-administered measure for depression; and Young Mania Rating Scale (YMRS) as a clinician-administered instrument for mania. Although the rating scales for mood represent a well-trodden terrain, this brief review of the most frequently used scales in the literature revealed there is still some room for improvement and for further research, especially with regard to their clinical interpretability. Copyright 2010 Elsevier Inc. All rights reserved.

  9. 76 FR 30934 - Combined Notice of Filings #1

    Science.gov (United States)

    2011-05-27

    ... 19, 2011. Docket Numbers: EC11-84-000. Applicants: Montgomery L'Energia Power Partners LP, Tanner... Montgomery L'Energia Power Partners LP, et. al. Filed Date: 05/23/2011. Accession Number: 20110523-5016...

  10. 76 FR 54754 - Combined Notice of Filings #1

    Science.gov (United States)

    2011-09-02

    ...: Montgomery L'Energia Power Partners LP. Description: Notice of Cancellation of FERC Electric Rate Schedule Tariff of Montgomery L'Energia Power Partners LP. Filed Date: 08/24/2011. Accession Number: 20110824-5095...

  11. Daily Arrests

    Data.gov (United States)

    Montgomery County of Maryland — This dataset provides the public with arrest information from the Montgomery County Central Processing Unit (CPU) systems. The data presented is derived from every...

  12. Geographic data: Zip Codes (Shape File)

    Data.gov (United States)

    Montgomery County of Maryland — This dataset contains all zip codes in Montgomery County. Zip codes are the postal delivery areas defined by USPS. Zip codes with mailboxes only are not included. As...

  13. Fiscal Year 2015 Budget

    Data.gov (United States)

    Montgomery County of Maryland — This dataset includes the Fiscal Year 2015 Council-approved operating budget for Montgomery County. The dataset does not include revenues and detailed agency budget...

  14. Road Closures

    Data.gov (United States)

    Montgomery County of Maryland — This is an up to date map of current road closures in Montgomery County.This dataset is updated every few minutes from the Department of Transportation road closure...

  15. Employee Travel Data (Non-Local)

    Data.gov (United States)

    Montgomery County of Maryland — ‘This dataset provides information regarding the total approved actual expenses incurred by Montgomery County government employees traveling non-locally (over 75...

  16. Smoking and Soldier Performance: A Literature Review.

    Science.gov (United States)

    1986-06-01

    smokers to be heavy users of coffee , . ., amphetamines, and tranquilizers although no comparison was made AIN with nonsmokers. Prendergast, Preble, and...Oreland (1985) studied 18-yr-olds in Sweden and found regular smokers were more prone to the abuse of alcohol, glue, cannabis , amphetamines, and morphine...laboratory and ’ found smokers took significantly longer to get to sleep than.-.--- nonsmokers (43.7 min versus 29.8 min). Although coffee ’ 7

  17. A comparison of iron oxide-rich joint coatings and rock chips as geochemical sampling media in exploration for disseminated gold deposits

    Science.gov (United States)

    Crone, W.; Larson, L.T.; Carpenter, R.H.; Chao, T.T.; Sanzolone, R.F.

    1984-01-01

    We evaluated the effectiveness of iron oxide-rich fracture coatings as a geochemical sampling medium for disseminated gold deposits, as compared with conventional lithogeochemical methods, for samples from the Pinson mine and Preble prospect in southeastern Humboldt County, Nevada. That disseminated gold mineralization is associated with Hg, As, and Sb is clearly demonstrated in these deposits for both fracture coatings and rock chip samples. However, the relationship is more pronounced for fracture coatings. Fracture coatings at Pinson contain an average of 3.61, 5.13, 14.37, and 3.42 times more Au, As, Sb and Hg, respectively, than adjacent rock samples. At Preble, fracture coatings contain 3.13, 9.72, 9.18, and 1.85 times more Au, As, Sb and Hg, respectively, than do adjacent rock samples. Geochemical anomalies determined from fracture coatings are thus typically more intense than those determined from rock samples for these elements. The sizes of anomalies indicated by fracture coatings are also somewhat larger, but this is less obvious. In both areas, Sb anomalies are more extensive in fracture coatings. At Preble, some Hg and Au anomalies are also more extensive in fracture coatings. In addition to halos formed by the Hg, As and Sb, high values for Au/Ag and Zn/(Fe + Mn) are closely associated with gold mineralization at the Pinson mine. The large enhancement in geochemical response afforded by fracture coatings indicates a definite potential in the search for buried disseminated gold deposits. ?? 1984.

  18. Three high-school students from Fairfield College in Hamilton, New Zealand, visited CERN on 6 June after winning first prize in a scientific-film competition promoted by the Royal Society of New Zealand for World Year of Physics

    CERN Document Server

    Maximilien Brice

    2005-01-01

    The reward for their documentary on physicist and winner of the Nobel Prize for Medicine, Maurice Wilkins, was a trip to Italy and Switzerland, including a stop at CERN. After breakfast with the director-general, Robert Aymar, the students were shown around the antiproton decelerator and the CMS experiment, accompanied by one of their teachers and a science journalist. Pictures 01, 04, 05, 09 : with their teacher Noema Watene

  19. Nutritional evaluation of groundnut oil cake in formulated diets for rohu, Labeo rohita (Hamilton fingerlings after solid state fermentation with a tannase producing yeast, Pichia kudriavzevii (GU939629 isolated from fish gut

    Directory of Open Access Journals (Sweden)

    Koushik Ghosh

    2015-11-01

    Full Text Available De-oiled groundnut oil cake (GOC was bio-processed through solid state fermentation (SSF for 15 days at 34 ± 1 °C by a tannase producing yeast, Pichia kudriavzevii (GU939629 isolated from the gut of a freshwater carp, Cirrhinus cirrhosus. SSF of GOC was effective in significantly (P < 0.05 reducing crude fibre content and antinutritional factors (e.g., tannin, phytic acid and trypsin inhibitor, whereas enhancing crude protein, lipid, ash, total free amino acids and fatty acids. Bio-processing revealed significant increase in the levels of argenine, histidine, isoleusine, lysine, methyonine and threonine in the GOC. Eight isonitrogenous (37.5% and isocaloric (18.8 kJ g−1 experimental diets were prepared incorporating raw (R1–R4 and fermented (F1–F4 GOC at 20%, 30%, 40% and 50% levels by weight replacing fishmeal and other feed ingredients into a fishmeal-based reference diet (RD and fed to rohu, Labeo rohita, fingerlings (initial weight 3.24 ± 0.11 g for 80 days. In general, diets with SSF-processed GOC produced significantly better performance than the raw GOC in terms of growth, feed utilization, nutrient digestibility, carcass composition and digestive enzyme activity. Rohu fingerlings fed the diet F3 containing 40% fermented GOC resulted in best performance in terms of weight gain (final weight 7.08 ± 0.06 g, specific growth rate (% day−1, protein efficiency ratio and apparent net protein utilization. Highest protein (14.93 ± 0.51% and lipid deposition in the carcass were also recorded in the group of fish reared on diet F3. In comparison to the FM based reference diet, the present study explored the possibility of replacing 45–55% of FM through incorporation of 40–50% (w/w SSF-processed GOC in the diets for rohu fingerlings.

  20. Vilazodone for the treatment of depression.

    Science.gov (United States)

    Lindsey, Wesley T

    2011-07-01

    To evaluate the clinical literature on and potential clinical role of vilazodone for the treatment of major depressive disorder. Searches were conducted on MEDLINE (1948-February 2011), Iowa Drug Information Service (1988-February 2011), EBSCO Academic Search Premier (1975-February 2011), Google Scholar (1992-February 2011), PsycINFO (1980-February 2011), and PsycARTICLES (1985-February 2011), and on general Internet search engines including Google and Bing (no lower limit-February 2011). Search terms were vilazodone, EMD 68843, depression, and major depressive disorder. Potential prior marketers of vilazodone, including Merck KGaA in Germany and Genaissance Pharmaceuticals, were contacted for any available unpublished Phase 1, Phase 2, Phase 3 studies, or preclinical information. All applicable full-text English-language articles, abstracts, and professional poster presentations found were evaluated and included in the review, as well as marketing and Securities and Exchange Commission filings available from the patent holders. Vilazodone is an antidepressant recently approved by the Food and Drug Administration (FDA) that is first in a new class regarding mechanism of action. It has demonstrated efficacy in the primary outcome of the Montgomery-Asberg Depression Rating Scale (MADRS) response in an 8-week pivotal Phase 3 trial. Phase 2 trials did not demonstrate efficacy for primary outcomes of the 17-item Hamilton Rating Scale for Depression but showed statistically significant improvements in select secondary outcomes such as Clinical Global Impressions severity and MADRS. Long-term efficacy data are still forthcoming. An emerging aspect to vilazodone's development has been the identification and assessment of potential genetic biomarkers associated with both therapeutic response and more serious adverse effects. Initial studies into biomarkers have been inconclusive. Vilazodone is a new agent recently approved by the FDA for treating major depressive disorder

  1. Effect of aerobic training on EEG alpha asymmetry and depressive symptoms in the elderly: a 1-year follow-up study

    Directory of Open Access Journals (Sweden)

    A.C. Deslandes

    2010-06-01

    Full Text Available The effect of physical exercise on the treatment of depressive elderly adults has not been investigated thus far in terms of changes in cortical hemispheric activity. The objective of the present study was to identify changes in depressive symptoms, quality of life, and cortical asymmetry produced by aerobic activity. Elderly subjects with a diagnosis of major depressive disorder (DSM-IV were included. Twenty patients (70% females, 71 ± 3 years were divided into an exercise group (pharmacological treatment plus aerobic training and a control group (undergoing pharmacological treatment in a quasi-experimental design. Pharmacological treatment was maintained stable throughout the study (antidepressants and anxiolytics. Subjects were evaluated by depression scales (Beck Depression Inventory, Hamilton Depression Rating Scale, Montgomery-Asberg Depression Rating Scale and the Short Form Health Survey-36, and electroencephalographic measurements (frontal and parietal alpha asymmetry before and after 1 year of treatment. After 1 year, the control group showed a decrease in cortical activity on the right hemisphere (increase of alpha power, which was not observed in the exercise group. The exercise group showed a significant decrease of depressive symptoms, which was not observed in the control group. This result was also accompanied by improved treatment response and remission rate after 1 year of aerobic exercise associated with treatment. This study provides support for the effect of aerobic training on alpha activity and on depressive symptoms in elderly patients. Exercise facilitates the treatment of depressive elderly adults, leading to clinical and physical improvement and protecting against a decrease in cortical activity.

  2. Safety and efficacy of quetiapine in bipolar depression.

    Science.gov (United States)

    Bogart, Gregory T; Chavez, Benjamin

    2009-11-01

    To review the clinical data investigating the efficacy and safety of quetiapine in bipolar depression. Searches of MEDLINE and PubMed (1977-July 2009) were conducted using the key words quetiapine and bipolar depression. The references of literature found were cross-referenced. The pharmaceutical company that produces quetiapine was contacted to obtain the posters for the EMBOLDEN I and EMBOLDEN II trials. Only double-blind, placebo-controlled trials were included for review, as well as any subanalyses of the literature that matched this criterion. There was a total of 5 double-blind, placebo-controlled trials and 5 subanalyses reviewed. The results of these data demonstrated quetiapine's efficacy in the treatment of depressive phases of bipolar disorder, including statistically significant improvement in the Montgomery-Asberg Depression Rating Scale (MADRS). In the trials reviewed in this article, the change in MADRS scores ranged from -15.4 to -16.94 within the quetiapine groups, and from -10.26 to -11.93 in the placebo groups. There were also statistically significant improvements in the Hamilton Anxiety Rating Scale, the Short Form of the Quality of Life Enjoyment and Satisfaction Questionnaire, the Pittsburgh Sleep Quality Index, and the Sheehan Disability Scale. All of these trials had a duration of 8 weeks and therefore cannot be applied to the long-term use of quetiapine in bipolar depression. The most common adverse events were sedation, somnolence, and dry mouth. The overall dropout rates for the trials reviewed ranged from 24% to 47%. Based on the literature reviewed here, quetiapine appears to be a safe and efficacious short-term treatment option for bipolar depression. Patients with bipolar type I showed greater improvement on the MADRS than those with bipolar type II. Patients with a rapid-cycling disease course showed an improvement in depressive symptoms, regardless of bipolar type.

  3. Transcultural adaption and validation of the Spanish version of the Bipolar Depression Rating Scale (BDRS-S).

    Science.gov (United States)

    Sarró, Salvador; Madre, Mercè; Fernández-Corcuera, Paloma; Valentí, Marc; Goikolea, José M; Pomarol-Clotet, Edith; Berk, Michael; Amann, Benedikt L

    2015-02-01

    The Bipolar Depression Rating Scale (BDRS) arguably better captures symptoms in bipolar depression especially depressive mixed states than traditional unipolar depression rating scales. The psychometric properties of the Spanish adapted version, BDRS-S, are reported. The BDRS was translated into Spanish by two independent psychiatrists fluent in English and Spanish. After its back-translation into English, the BDRS-S was administered to 69 DSMI-IV bipolar I and II patients who were recruited from two Spanish psychiatric hospitals. The Hamilton Depression Rating Scale (HDRS), the Montgomery-Asberg Depression Rating Scale (MADRS) and the Young Mania Rating Scale (YMRS) were concurrently administered. 42 patients were reviewed via video by four psychiatrists blind to the psychopathological status of those patients. In order to assess the BDRS-S intra-rater or test-retest validity, 22 subjects were assessed by the same investigator performing two evaluations within five days. The BDRS-S had a good internal consistency (Cronbach׳s α=0.870). We observed strong correlations between the BDRS-S and the HDRS (r=0.874) and MADRS (r=0.854) and also between the mixed symptom cluster score of the BDRS-S and the YMRS (r=0.803). Exploratory factor analysis revealed a three factor solution: psychological depressive symptoms cluster, somatic depressive symptoms cluster and mixed symptoms cluster. A relatively small sample size for a 20-item scale. The BDRS-S provides solid psychometric performance and in particular captures depressive or mixed symptoms in Spanish bipolar patients. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Evaluation of the influence of ayurvedic formulation (Ayushman-15) on psychopathology, heart rate variability and stress hormonal level in major depression (Vishada).

    Science.gov (United States)

    Kishore, Ramakrishna K; Abhishekh, Hulegar A; Udupa, Kaviraja; Thirthalli, Jagadisha; Lavekar, Gandhidas S; Gangadhar, Bangalore N; Raju, Trichur R; Sathyaprabha, Talakad N

    2014-12-01

    Ayurveda (Indian-complimentary and alternative medicine) is still most sought after in India and has promising potential in management of Vishada [major depressive disorder (MDD)]. But, systematic research is lacking. In this study we evaluated of influence of ayurvedic treatment (Panchakarma and Ayushman-15) on psychopathology, heart rate variability (HRV) and endocrinal parameters in patients with major depression. 81 drug naive patients diagnosed as Vishada by ayurvedic physician and MDD according to DSM IV-TR were given ayurvedic Virechana module (therapeutic purgation) and were randomized into two groups. Patients in group A (n=41) received Ayushman-15A while group B (n=40) received Ayushman-15B for two months and Shirodhara (forehead-oil pouring therapy). Patients were assessed with Hamilton Depression Rating Scale (HDRS), Montgomery Asberg Depression Rating Scale (MADRS), Heart Rate Variability (HRV). Cortisol and adrenocorticotropic hormone (ACTH) were estimated at baseline and after ayurvedic therapy. HRV and endocrinal parameters were compared with age and gender matched healthy volunteers. HRV parameters showed significant sympathetic dominance in patients compared to healthy volunteers. Two months of ayurvedic treatment significantly decreased psychopathology, showed increase in vagal tone, decrease in sympathetic tone and reduced cortisol levels. However, there was no significant difference between groups receiving Ayushman A and B. This study provides evidence for antidepressant, cardiac (HRV) and beneficial neuroendocrine modulatory influence of Ayurveda therapy in patients of Vishada (MDD). Further studies are needed to confirm these findings. Greater insight into the neurobiology behind this therapy might provide valuable information about newer drug target. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. Escitalopram treatment for depressive disorder following acute coronary syndrome: a 24-week double-blind, placebo-controlled trial.

    Science.gov (United States)

    Kim, Jae-Min; Bae, Kyung-Yeol; Stewart, Robert; Jung, Bo-Ok; Kang, Hee-Ju; Kim, Sung-Wan; Shin, Il-Seon; Hong, Young Joon; Kim, Ju Han; Shin, Hee-Young; Kang, Gaeun; Ahn, Youngkeun; Kim, Jong-Keun; Jeong, Myung Ho; Yoon, Jin-Sang

    2015-01-01

    Depression is common after acute coronary syndrome (ACS) and has adverse effects on prognosis. There are few evidence-based interventions for treating depression in ACS. This study investigated the efficacy and safety of escitalopram in treating depressive disorders identified 2-14 weeks after a confirmed ACS episode. A total of 217 patients with DSM-IV depressive disorders (121 major and 96 minor) and ACS were randomly assigned to receive escitalopram in flexible doses of 5-20 mg/d (n = 108) or placebo (n = 109) for 24 weeks. The study was conducted from 2007 to 2013. The primary outcome measure was the Hamilton Depression Rating Scale (HDRS). Secondary outcome measures included the Montgomery-Asberg Depression Rating Scale (MADRS), Beck Depression Inventory (BDI), Clinical Global Impressions-Severity of Illness scale (CGI-S), Social and Occupational Functioning Assessment Scale (SOFAS), and World Health Organization Disability Assessment Schedule-12. Cardiovascular safety outcomes included echocardiography, electrocardiography, laboratory test, body weight, and blood pressure results. Escitalopram was superior to placebo in reducing HDRS scores (mean difference = 2.3, P = .016, effect size = 0.38). Escitalopram was also superior to placebo in decreasing depressive symptoms evaluated by the MADRS, BDI, and CGI-S and in improving SOFAS functioning level. Escitalopram was not associated with any harmful changes in cardiovascular safety measures. Dizziness was significantly more frequently reported in the escitalopram group (P = .018), but there were no significant differences in any other adverse events. These results indicate that escitalopram has clinically meaningful antidepressant effects with no evidence of reduced cardiovascular safety in depressive disorder following ACS. ClinicalTrials.gov identifier: NCT00419471. © Copyright 2015 Physicians Postgraduate Press, Inc.

  6. Effects of quetiapine on sleep architecture in patients with unipolar or bipolar depression

    Directory of Open Access Journals (Sweden)

    Laura Gedge

    2010-08-01

    Full Text Available Laura Gedge1, Lauren Lazowski1, David Murray2, Ruzica Jokic2,3, Roumen Milev2,31Centre for Neuroscience Studies, 2Department of Psychiatry, Queen’s University, Kingston, 3Providence Care-Mental Health Services, Kingston, Ontario, CanadaObjective: To determine the effect of adjunctive quetiapine therapy on the sleep architecture of patients with bipolar or unipolar depression.Methods: This is a prospective, single-blind, repeated measures polysomnographic study. Sleep architecture was analyzed by overnight polysomnography, and subjective sleep quality was measured using the Pittsburgh Sleep Quality Index. The Hamilton Rating Scale for Depression, Montgomery Asberg Depression Rating Scale, Young Mania Rating Scale, and Clinical Global Impression-Severity Scale were employed to quantify changes in illness severity with adjunctive quetiapine treatment. Polysomnographs and clinical measures were administered at baseline, after 2–4 days of treatment, and after 21–28 days of quetiapine treatment. The average dose of quetiapine was 155 mg, ranging from 100–200 mg.Results: Adjunctive quetiapine therapy did not significantly alter sleep efficiency, sleep continuity, or Pittsburgh Sleep Quality Index scores. Respiratory Disturbance Index and percentage of total time in rapid eye movement (REM sleep significantly decreased and the percentage of total time in non-REM sleep, and duration of Stage 2 and non-REM sleep significantly increased after 2–4 days of quetiapine treatment. Illness severity significantly decreased over time.Conclusions: Adjunctive quetiapine treatment alters sleep architecture in patients with major depressive disorder or bipolar disorder, which may partially explain its early antidepressant properties. Changes in sleep architecture are more robust and significant within two to four days of starting treatment.Keywords: quetiapine, sleep architecture, depression, bipolar disorder

  7. Neuropsychological rehabilitation of memory deficits and activities of daily living in patients with Alzheimer's disease: a pilot study

    Directory of Open Access Journals (Sweden)

    Ávila R.

    2004-01-01

    Full Text Available Patients with Alzheimer's disease (AD gradually lose their cognitive competence, particularly memory, and the ability to perform daily life tasks. Neuropsychological rehabilitation is used to improve cognitive functions by facilitating memory performance through the use of external aids and internal strategies. The effect of neuropsychological rehabilitation through memory training - motor movements, verbal association, and categorization - and activities of daily living (ADL training was tested in a sample of 5 elderly out-patients (mean age: 77.4 ± 2.88 years, with mild AD (Mini-Mental State Examination score: 22.20 ± 2.17 and their caregivers. All patients had been taking rivastigmine (6-12 mg/day for at least 3 months before being assigned to the rehabilitation sessions, and they continued to take the medication during the whole program. Just before and after the 14-week neuropsychological rehabilitation program all patients were assessed by interviewers that did not participate in the cognitive training, using the Mini-Mental State Examination, Montgomery-Alsberg Depression Rating Scale, Hamilton Anxiety Scale, Interview to Determine Deterioration in Functioning in Dementia, Functional Test, Memory Questionnaire of Daily Living for patient and caregiver, Quality of Life Questionnaire for patient and caregiver, and a neuropsychological battery. The results showed a statistically significant improvement in ADL measured by Functional Test (P = 0.04, and only a small improvement in memory and psychiatric symptoms. Our results support the view that weekly stimulation of memory and training of ADL is believed to be of great value in AD treatment, not only delaying the progress of the disease, but also improving some cognitive functions and ADL, even though AD is a progressively degenerative disease.

  8. Acute and long-term treatment of late-life major depressive disorder: duloxetine versus placebo.

    Science.gov (United States)

    Robinson, Michael; Oakes, Tina Myers; Raskin, Joel; Liu, Peng; Shoemaker, Scarlett; Nelson, J Craig

    2014-01-01

    To compare the efficacy of duloxetine with placebo on depression in elderly patients with major depressive disorder. Multicenter, 24-week (12-week short-term and 12-week continuation), randomized, placebo-controlled, double-blind trial. United States, France, Mexico, Puerto Rico. Age 65 years or more with major depressive disorder diagnosis (one or more previous episode); Mini-Mental State Examination score ≥20; Montgomery-Asberg Depression Rating Scale total score ≥20. Duloxetine 60 or 120 mg/day or placebo; placebo rescue possible. Primary-Maier subscale of the 17-item Hamilton Depression Rating Scale (HAMD-17) at week 12. Secondary-Geriatric Depression Scale, HAMD-17 total score, cognitive measures, Brief Pain Inventory (BPI), Numeric Rating Scales (NRS) for pain, Clinical Global Impression-Severity scale, Patient Global Impression of Improvement in acute phase and acute plus continuation phase of treatment. Compared with placebo, duloxetine did not show significantly greater improvement from baseline on Maier subscale at 12 weeks, but did show significantly greater improvement at weeks 4, 8, 16, and 20. Similar patterns for Geriatric Depression Scale and Clinical Global Impression-Severity scale emerged, with significance also seen at week 24. There was a significant treatment effect for all BPI items and 4 of 6 NRS pain measures in the acute phase, most BPI items and half of the NRS measures in the continuation phase. More duloxetine-treated patients completed the study (63% versus 55%). A significantly higher percentage of duloxetine-treated patients versus placebo discontinued due to adverse event (15.3% versus 5.8%). Although the antidepressant efficacy of duloxetine was not confirmed by the primary outcome, several secondary measures at multiple time points suggested efficacy. Duloxetine had significant and meaningful beneficial effects on pain. Copyright © 2014 American Association for Geriatric Psychiatry. Published by Elsevier Inc. All rights

  9. A double-blind randomized placebo-controlled pilot study of neuropsychiatric adverse events in abstinent smokers treated with varenicline or placebo.

    Science.gov (United States)

    Garza, Dahlia; Murphy, Michael; Tseng, Li-Jung; Riordan, Henry J; Chatterjee, Anjan

    2011-06-01

    Varenicline is an α4β2 partial nicotinic agonist approved for smoking cessation. There have been spontaneous postmarketing reports of neuropsychiatric adverse events (NPAEs) in smokers without a history of psychiatric illness quitting with varenicline. One hundred ten smokers without history of psychiatric illness (screened by Structured Clinical Interview for DSM-IV) were randomized to 12 weeks of varenicline 1 mg twice daily (n = 55) or placebo. Adverse events were solicited systematically. Depressive symptoms, anxiety, aggression, and irritability were measured at baseline and weekly using the Montgomery-Åsberg Depression Rating Scale (MADRS), the Hamilton Anxiety Scale (HAM-A), and the Overt Aggression Scale-Modified (OAS-M). The Profile of Mood States (POMS) was administered daily. Mixed-model analysis of repeated measures was conducted to compare mean changes in scores between groups across study periods. Participants' mean baseline characteristics were 33 years of age, 22 cigarettes/day and Fagerström Test for Nicotine Dependence score > 7. Reported NPAEs were similar between groups. No suicidal events were reported. There were no significant differences between groups for the MADRS (treatment difference vs. placebo = .03, 95% confidence interval [CI] -.68-.73; NS), HAM-A (treatment difference [TD] = .14, 95% CI -.62-.90; NS), OAS-M Aggression subscale (TD = .5, 95% CI -1.18-2.18; NS), OAS-M Irritability subscale (TD = .08, 95% CI -.17-.34; NS), and the POMS total scores (TD = .5, 95% CI -.52-1.53; NS). There were no significant differences between groups on measures of depressive symptoms, anxiety, or aggression/hostility. Systematically solicited NPAEs were similar between the varenicline and placebo groups. Copyright © 2011 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  10. Are self-report scales as effective as clinician rating scales in measuring treatment response in routine clinical practice?

    Science.gov (United States)

    Zimmerman, Mark; Walsh, Emily; Friedman, Michael; Boerescu, Daniela A; Attiullah, Naureen

    2018-01-01

    Recent treatment guidelines have suggested that outcome should be measured in routine clinical practice. In the present report from the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) project, we compared three self-report scales of depressive symptoms and the two most widely used clinician administered scales in treatment studies in their sensitivity to change and evaluation of treatment response in depressed patients treated in routine practice. At baseline and 4-month follow-up 153 depressed outpatients with DSM-IV MDD completed the Clinically Useful Depression Outcome Scale (CUDOS), Quick Inventory of Depressive Symptomatology-Self-report version (QIDS-SR), and Patient Health Questionnaire (PHQ-9). The patients were rated on the 17-item Hamilton Depression Rating Scale (HAMD) and the Montgomery-Asberg Depression Rating Scale (MADRS). On each scale treatment response was defined as a 50% or greater reduction in scores from baseline. While there were some differences in the percentage of patients considered to be responders on the different scales, a large effect size was found for each scale, with little variability amongst the scales. The level of agreement between the three self-report scales and the clinician rating scales was approximately the same LIMITATIONS: The present study was conducted in a single clinical practice in which the majority of the patients were white, female, and had health insurance. When measuring outcome in clinical practice the magnitude of change in depressive symptoms is as great on self-report scales as on clinician rating scales. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Impact of anxiety symptoms on outcomes of depression: an observational study in Asian patients

    Directory of Open Access Journals (Sweden)

    Novick D

    2016-04-01

    Full Text Available Diego Novick,1 William Montgomery,2 Jaume Aguado,3 Xiaomei Peng,4 Josep Maria Haro3 1Eli Lilly and Company, Windlesham, Surrey, UK; 2Eli Lilly Australia Pty Ltd, West Ryde, NSW, Australia; 3Parc Sanitari Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Barcelona, Spain; 4Eli Lilly and Company, Indianapolis, IN, USA Objective: To investigate the impact of anxiety symptoms on depression outcomes in Asian patients with major depressive disorder (MDD (n=714. Methods: The 17-item Hamilton Depression Scale (HAMD-17, overall severity, somatic symptoms, and quality of life (QOL (EuroQOL Questionnaire-5 Dimensions [EQ-5D] were assessed at baseline and 3 months. Anxiety was measured using items 10 and 11 from the HAMD-17. Linear, tobit, and logistic multiple regression models analyzed the impact of anxiety symptoms on outcomes. Baseline anxiety was related to age and the presence of pain symptoms at baseline. Results: Regression models showed that a higher level of anxiety was associated with a lower frequency of remission and lower QOL at 3 months. Patients with lower baseline anxiety symptoms had higher remission rates (odds ratio for each point of anxiety symptoms, 0.829 [95% confidence interval [CI]: 0.723–0.951]. Patients with higher levels of baseline anxiety had a lower QOL at 3 months (a decrease in EQ-5D tariff score for each point of anxiety symptoms, 0.023 [95% CI: 0.045–0.001]. Conclusion: In conclusion, the presence of anxiety symptoms negatively impacts the outcomes of depression. Keywords: depression, anxiety, Asia, observational, outcomes

  12. Why Was General Richard O’Connor’s Command in Northwest Europe Less Effective Than Expected?

    Science.gov (United States)

    2011-03-01

    Commander of 7 Division and Military Governor of Jerusalem , September 1938- August 1939. ______. Papers of General Sir Richard O’Connor KT, GCB, DSO, MC...Montgomery, Brian. A Field Marshall in the Family: A Personal Biography of Montgomery of Alamein. New York: Taplinger, 1973. Montgomery, Field...Commanders: A Composite Biography . Combat Studies Institute publications, Fort Leavenworth, Kansas: U.S. Army Command and General Staff College, 1989

  13. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available ... Autogenic Drainage Positive Expiratory Pressure High-Frequency Chest Wall Oscillation (the Vest) ... Cystic Fibrosis Foundation 4550 Montgomery Ave. Suite 1100 N Bethesda, MD ...

  14. 78 FR 25755 - Announcement of Funding Awards; Energy Innovation Fund-Multifamily Pilot Program Fiscal Year 2010

    Science.gov (United States)

    2013-05-02

    ... Community Place, 7441. Cecil, Frederick, Crownsville, MD 21032. Hartford, Howard, Montgomery, Prince George... Greater Portland, OR 1020 SW Taylor, Suite 585, Portland, 5680. metropolitan area. Oregon 97205. NRG...

  15. 77 FR 16316 - Kentucky Disaster Number KY-00044

    Science.gov (United States)

    2012-03-20

    ... Counties: (Physical Damage and Economic Injury Loans): Bath, Campbell, Carroll, Grant, Martin, Montgomery... Assistance Numbers 59002 and 59008) Joseph P. Loddo, Acting Associate Administrator for Disaster Assistance...

  16. Recreation Summer Camps

    Data.gov (United States)

    Montgomery County of Maryland — List of all Camps (Register here:https://apm.activecommunities.com/montgomerycounty/Home) to include Aquatics, Basketball, Soccer, Special Interest, General Sports,...

  17. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Montgomery College Center for the Advancement of Distance Education University of Southern California, Maternal Child & Adolescent Program University of Illinois Chicago, Center of Excellence in ...

  18. 76 FR 59177 - New York Disaster #NY-00110

    Science.gov (United States)

    2011-09-23

    ... York: Chemung, Cortland, Greene, Herkimer, Madison, Montgomery, Oneida, Schoharie, Sullivan, Tompkins... Federal Domestic Assistance Numbers 59002 and 59008) James E. Rivera, Associate Administrator for Disaster...

  19. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Legislators (NFWL) Educational Institutions: Florida International University Montgomery College Center for the Advancement of Distance Education University of Southern California, Maternal Child & Adolescent Program ...

  20. Internal Affairs Allegations

    Data.gov (United States)

    Montgomery County of Maryland — This dataset contains allegations brought to the attention of the Internal Affairs Division either through external complaints or internal complaint or recognition....

  1. DEP Reported Sanitary Sewer Overflows

    Data.gov (United States)

    Montgomery County of Maryland — Sanitary sewer overflows reported to the Department of Environmental Protection by the Washington Suburban Sanitary Commission or individuals in the County. Update...

  2. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Montgomery College Center for the Advancement of Distance Education University of Southern California, Maternal Child & Adolescent Program University of Illinois Chicago, Center of ...

  3. Commentary on "a matched comparison of perioperative outcomes of a single laparoscopic surgeon versus a multisurgeon robot-assisted cohort for partial nephrectomy." Ellison JS, Montgomery JS, Wolf Jr JS, Hafez KS, Miller DC, Weizer AZ, Department of Urology, University of Michigan, Ann Arbor, MI, USA: J Urol 2012;188(1):45-50.

    Science.gov (United States)

    Kane, Christopher

    2013-02-01

    Minimally invasive nephron sparing surgery is gaining popularity for small renal masses. Few groups have evaluated robot-assisted partial nephrectomy compared to other approaches using comparable patient populations. We present a matched pair analysis of a heterogeneous group of surgeons who performed robot-assisted partial nephrectomy and a single experienced laparoscopic surgeon who performed conventional laparoscopic partial nephrectomy. Perioperative outcomes and complications were compared. All 249 conventional laparoscopic and robot-assisted partial nephrectomy cases from January 2007 to June 2010 were reviewed from our prospectively maintained institutional database. Groups were matched 1:1 (108 matched pairs) by R.E.N.A.L. (radius, exophytic/endophytic properties, nearness of tumor to collecting system or sinus, anterior/posterior, location relative to polar lines) nephrometry score, transperitoneal vs retroperitoneal approach, patient age and hilar nature of the tumor. Statistical analysis was done to compare operative outcomes and complications. Matched analysis revealed that nephrometry score, age, gender, tumor side and American Society of Anesthesia physical status classification were similar. Operative time favored conventional laparoscopic partial nephrectomy. During the study period robot-assisted partial nephrectomy showed significant improvements in estimated blood loss and warm ischemia time compared to those of the experienced conventional laparoscopic group. Postoperative complication rates, and complication distributions by Clavien classification and type were similar for conventional laparoscopic and robot-assisted partial nephrectomy (41.7% and 35.0%, respectively). Robot-assisted partial nephrectomy has a noticeable but rapid learning curve. After it is overcome the robotic procedure results in perioperative outcomes similar to those achieved with conventional laparoscopic partial nephrectomy done by an experienced surgeon. Robot-assisted partial nephrectomy likely improves surgeon and patient accessibility to minimally invasive nephron sparing surgery. Copyright © 2013 Elsevier Inc. All rights reserved.

  4. University Student and Faculty Opinions on Academic Integrity Are Informed by Social Practices or Personal Values, A Review of: Randall, Ken, Denise G. Bender and Diane M. Montgomery. “Determining the Opinions of Health Sciences Students and Faculty Regarding Academic Integrity.” International Journal for Educational Integrity 3.2 (2007): 27‐40.

    OpenAIRE

    Matthew Thomas

    2009-01-01

    Objective – To understand the opinions of students and faculty in physical therapy (PT) and occupational therapy (OT) regarding issues of academic integrity such as plagiarism and cheating.Design – Q method (a mixed method of qualitative data collection with application of quantitative methods to facilitate grouping and interpretation).Setting – An urban university‐affiliated health sciences facility in the mid‐western United States.Subjects – Thirty‐three students and five faculty members of...

  5. University Student and Faculty Opinions on Academic Integrity Are Informed by Social Practices or Personal Values, A Review of: Randall, Ken, Denise G. Bender and Diane M. Montgomery. “Determining the Opinions of Health Sciences Students and Faculty Regarding Academic Integrity.” International Journal for Educational Integrity 3.2 (2007: 27‐40.

    Directory of Open Access Journals (Sweden)

    Matthew Thomas

    2009-09-01

    Full Text Available Objective – To understand the opinions of students and faculty in physical therapy (PT and occupational therapy (OT regarding issues of academic integrity such as plagiarism and cheating.Design – Q method (a mixed method of qualitative data collection with application of quantitative methods to facilitate grouping and interpretation.Setting – An urban university‐affiliated health sciences facility in the mid‐western United States.Subjects – Thirty‐three students and five faculty members of ages 21 to 61 years, 30 associated with the physical therapy program and 8 with occupational therapy, including 6 males and 32 females.Methods – Initially, 300 opinion statements for, against, or neutral on the subject of academic integrity were gathered from journal articles, editorials and commentaries, Internet sites, and personal web logs, 36 of which were selected to represent a full spectrum of perspectives on the topic. Participants in the study performed a “Q‐sort” in which they ranked the 36 statements as more‐like or less‐like their own values. A correlation matrix was developed based on the participantsʹ rankings to create “factors” or groups of individuals with similar views. Two such groups were found and interpreted qualitatively to meaningfully describe the differing views of each group. Three participants could not be sorted into either group, being split between the factors. Main Results – Analysis of the two groups, using software specific to the Q method, revealed a good deal of consensus, particularly in being “most unlike” those statements in support of academic dishonesty. The two groups differed primarily in the motivation for academic honesty. Factor one, with 21 individuals, was labeled “Collective Integrity,” (CI being represented by socially oriented statements such as “I believe in being honest, true, virtuous, and in doing good to all people,” or “My goal is to help create a world where all people are treated with fairness, decency, and respect.” Factor two, with 14 individuals, was described as “Personal Integrity,” (PI, and focused on an internal sense of values and self‐modulation, identifying with statements like “Honour means having the courage to make difficult choices and accepting responsibility for actions and their consequences, even at personal cost.” There were also some demographic patterns in the results. Twenty of the 31 students, 20 of the 29 females, and 17 of the 25 participants aged 30 and under were in the CI group, while 3 of the 4 faculty were in PI. Males, occupational therapists, physical therapists, and those over the age of 30 did not belong clearly to one or the other group, having close to equal numbers in both.Conclusion – Given the two factors, CI and PI, this sample of OT and PT students and faculty can be seen to make academic decisions based on either what they believe society deems correct or what their own internal values tell them. The discovery that more females, students, and those 30 and under were associated with CI resonates with the some key claims in the literature, such as that younger individuals tend to have a more social outlook on academic integrity, or that womenʹs ethic of care is often focused on connections among people. Most importantly, students and faculty appear to share a notable degree of common ground as it relates to their opinions on academic integrity. Additional exploration and the continued use and development of policies promoting academic integrity is called for.

  6. 76 FR 21232 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Science.gov (United States)

    2011-04-15

    ..., AL, Jack Edwards, ILS OR LOC RWY 27, Amdt 1 Gulf Shores, AL, Jack Edwards, RNAV (GPS) RWY 9, Amdt 3 Gulf Shores, AL, Jack Edwards, RNAV (GPS) RWY 27, Amdt 2 Montgomery, AL, Montgomery Rgnl (Dannelly... Williams Memorial, RNAV (GPS) RWY 24, Amdt 1 Vineyard Haven, MA, Marthas Vineyard, RNAV (GPS) RWY 6, Amdt 1...

  7. Baseline report - tall upland shrubland at the Rocky Flats Environmental Technology Site

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    Rocky Flats Environmental Technology Site (Site) is located on the Colorado Piedmont east of the Front Range between Boulder and Golden. At an elevation of approximately 6,000 feet, the Site contains a unique ecotonal mixture of mountain and prairie plant species, resulting from the topography and close proximity to the mountain front. The Buffer Zone surrounding the Industrial Area is one of the largest remaining undeveloped areas of its kind along the Colorado Piedmont. A number of plant communities at the Site have been identified as increasingly rare and unique by Site ecologists and the Colorado Natural Heritage Program (CNHP). These include the xeric tallgrass prairie, tall upland shrubland, wetlands, and Great Plains riparian woodland communities. Many of these communities support populations of increasingly rare animals as well, including the Preble`s meadow jumping mouse, grasshopper sparrow, loggerhead shrike, Merriam`s shrew, black crowned night heron, and Hops blue and Argos skipper butterflies. One of the more interesting and important plant communities at the Site is the tall upland shrubland community. It has been generally overlooked by previous Site ecological studies, probably due to its relatively small size; only 34 acres total. Although mentioned in a plant community ordination study conducted by Clark et al. and also in the Site baseline ecological study, few data were available on this plant community before the present study.

  8. Sovereign debt threatens the Union: the genesis of a federation

    NARCIS (Netherlands)

    Loubert, A.

    2012-01-01

    Eurozone sovereign debt crisis - Europe's ‘Alexander Hamilton Moment’ - American sovereign debt crisis of 1780s - Articles of Confederation - U.S. Constitution - Assumption of states' debt - Constitutional transformation key factor in enabling Alexander Hamilton's debt restructuring.

  9. PsychotherapyPlus: augmentation of cognitive behavioral therapy (CBT) with prefrontal transcranial direct current stimulation (tDCS) in major depressive disorder-study design and methodology of a multicenter double-blind randomized placebo-controlled trial.

    Science.gov (United States)

    Bajbouj, Malek; Aust, Sabine; Spies, Jan; Herrera-Melendez, Ana-Lucia; Mayer, Sarah V; Peters, Maike; Plewnia, Christian; Fallgatter, Andreas J; Frase, Lukas; Normann, Claus; Behler, Nora; Wulf, Linda; Brakemeier, Eva-Lotta; Padberg, Frank

    2017-12-06

    Major Depressive Disorder (MDD) is one of the most prevalent psychiatric disorders worldwide. About 20-30% of patients do not respond to the standard psychopharmacological and/or psychotherapeutic interventions. Mounting evidence from neuroimaging studies in MDD patients reveal altered activation patterns in lateral prefrontal brain areas. Successful cognitive behavioral therapy (CBT) is associated with a recovery of these neural alterations. Moreover, it has been demonstrated that transcranial direct current stimulation (tDCS) is capable of influencing prefrontal cortex activity and cognitive functions such as working memory and emotion regulation. Thus, a clinical trial investigating the effects of an antidepressant intervention combining CBT with tDCS seems promising. The present study investigates the antidepressant efficacy of a combined CBT-tDCS intervention as compared to CBT with sham-tDCS or CBT alone. A total of 192 patients (age range 20-65 years) with MDD (Hamilton Depression Rating Scale Score ≥ 15, 21-item version) will be recruited at four study sites across Germany (Berlin, Munich, Tuebingen, and Freiburg) and randomly assigned to one of the following three treatment arms: (1) CBT + active tDCS; (2) CBT + sham-tDCS; and (3) CBT alone. All participants will attend a 6-week psychotherapeutic intervention comprising 12 sessions of CBT each lasting 100 min in a closed group setting. tDCS will be applied simultaneously with CBT. Active tDCS includes stimulation with an intensity of 2 mA for 30 min with the anode placed over F3 and the cathode over F4 according to the EEG 10-20 system, if assigned. The primary outcome measure is the change in Montgomery-Åsberg Depression Rating Scale scores from baseline to 6, 18, and 30 weeks after the first session. Participants also undergo pre- and post-treatment neuropsychological testing and functional magnetic resonance imaging (fMRI) to assess changes in prefrontal functioning and connectivity

  10. A budget-impact and cost-effectiveness model for second-line treatment of major depression.

    Science.gov (United States)

    Malone, Daniel C

    2007-07-01

    Depressed patients who initially fail to achieve remission when placed on a selective serotonin reuptake inhibitor (SSRI) may require a second treatment. The purpose of this study was to evaluate the effectiveness, cost, cost-effectiveness, and budget impact of second-line pharmacologic treatment for major depressive disorder (MDD). A cost-effectiveness analysis was conducted to evaluate second-line therapies (citalopram, escitalopram, fluoxetine, paroxetine, paroxetine controlled release [CR], sertraline, and venlafaxine extended release [XR]) for the treatment of depression. Effectiveness data were obtained from published clinical studies. The primary outcome was remission defined as a score of 7 or less on the Hamilton Rating Scale for Depression (HAM-D) or a score of 10 or less on the montgomery-Asberg Depression Rating Scale (MADRS) depression rating scales. The wholesale acquisition cost (WAC) for medications and medical treatment costs for depression were included. The perspective was derived from a managed care organization (MCO) with 500,000 members, a 1.9% annual incidence of depression, and treatment duration of 6 months. Assumptions included: second-line treatment is not as effective as first-line treatment, WAC price reflects MCO costs, and side effects were identical. Sensitivity analyses were conducted to determine variables that influenced the results. Second-line remission rates were 20.4% for venlafaxine XR, 16.9% for sertraline, 16.4% for escitalopram, 15.1% for generic SSRIs (weighted average), and 13.6% for paroxetine CR. Pharmacy costs ranged from $163 for generic SSRIs to $319 for venlafaxine SR. Total cost per patient achieving remission was $14,275 for venlafaxine SR, followed by $16,100 for escitalopram. The incremental cost-effectiveness ratio (ICER) for venlafaxine SR compared with generic SSRIs was $2,073 per patient achieving remission, followed by escitalopram with an ICER of $3,566. The model was most sensitive to other therapies

  11. No change in N-acetyl aspartate in first episode of moderate depression after antidepressant treatment: 1H magnetic spectroscopy study of left amygdala and left dorsolateral prefrontal cortex

    Directory of Open Access Journals (Sweden)

    Bajs Janović M

    2014-09-01

    Full Text Available Maja Bajs Janović,1,3 Petra Kalember,2 Špiro Janović,1,3 Pero Hrabač,2 Petra Folnegović Grošić,1 Vladimir Grošić,4 Marko Radoš,5 Neven Henigsberg2,61University Department of Psychiatry, Clinical Hospital Center Zagreb, Zagreb, 2Polyclinic Neuron, Croatian Institute for Brain Research, School of Medicine, University of Zagreb, Zagreb, 3University North, Varaždin, 4Psychiatric Hospital Sveti Ivan, Zagreb, 5University Department of Radiology, Clinical Hospital Center Zagreb, Zagreb, 6Psychiatric Clinic Vrapče, Zagreb, CroatiaBackground: The role of brain metabolites as biological correlates of the intensity, symptoms, and course of major depression has not been determined. It has also been inconclusive whether the change in brain metabolites, measured with proton magnetic spectroscopy, could be correlated with the treatment outcome. Methods: Proton magnetic spectroscopy was performed in 29 participants with a first episode of moderate depression occurring in the left dorsolateral prefrontal cortex and left amygdala at baseline and after 8 weeks of antidepressant treatment with escitalopram. The Montgomery-Asberg Depression Rating Scale, the Hamilton Rating Scale for Depression, and the Beck Depression Inventory were used to assess the intensity of depression at baseline and at the endpoint of the study. At endpoint, the participants were identified as responders (n=17 or nonresponders (n=12 to the antidepressant therapy. Results: There was no significant change in the N-acetyl aspartate/creatine ratio (NAA/Cr after treatment with antidepressant medication. The baseline and endpoint NAA/Cr ratios were not significantly different between the responder and nonresponder groups. The correlation between NAA/Cr and changes in the scores of clinical scales were not significant in either group. Conclusion: This study could not confirm any significant changes in NAA after antidepressant treatment in the first episode of moderate depression, or in

  12. Assessment of clinical depression comorbid with posttraumatic stress disorder

    Directory of Open Access Journals (Sweden)

    Simonović Maja

    2008-01-01

    Full Text Available Background/Aim. Comorbidity of the posttraumatic stress disorder (PTSD and depression is often recognized in the clinical practice. The aim of the paper was to determine the severity of depression and the group of symptoms which are the most prominent in clinical depression comorbid with PTSD. Methods. Totally 60 patients were assessed and divided into the experimental and control group using the Structured Clinical Interview for DSM-IV Axis I Disorders, Investigator Version (SCID-I, modified (SCID for DSM-IV and ICD-10 diagnostic criteria. The presence and the severity of the disorders were assessed by means of the following instruments: Clinician-Administrated PTSD Scale for DSM-IV (CAPS-DX, Montgomery-Asberg Depression Rating Scale (MADRS and 17-item Hamilton Rating Scale for Depression (HAMD. The differences between groups were evaluated using Student t test and by means of the correlation analysis of the data with p < 0.05. Results. The obtained results showed that depression witch was comorbid with PTSD was of significant clinical severity with 31.20 score on HAMD and 30.43 score on MADRS in PTSD-D group. The group of the symptoms: lassitude, inability to feel, suicidal thoughts and inner tension contributed mostly to the global severity of the comorbid clinical depression on MADRS. The group of the symptoms: suicide and somatic symptoms, gastrointestinal, guilt, hypochondriasis, work and activity, anxiety psychic, agitation, and weight loss, genital symptoms and anxiety somatic contributed mostly to the global severity of comorbid clinical depression on HAMD. The average score was 16.03 and 16.97 on HAMD and MADRS, respectively in PTSD group. Conclusion. Depression which is comorbid with posttraumatic stress disorder represents significant clinical entity with domination of the different groups of symptoms between the groups PTSD and PTSD-D on HAMD. Identification of aforementioned severity of illness and delineated group of symptoms lead

  13. Do concomitant pain symptoms in patients with major depression affect quality of life even when taking into account baseline depression severity?

    Directory of Open Access Journals (Sweden)

    Novick D

    2013-05-01

    Full Text Available Diego Novick,1 William Montgomery,2 Zbigniew Kadziola,3 Victoria Moneta,4 Xiaomei Peng,5 Roberto Brugnoli,6 Josep Maria Haro41Eli Lilly and Company, Windlesham, Surrey, UK; 2Eli Lilly Australia Pty Ltd, West Ryde, NSW, Australia; 3Eli Lilly Austria GmbH, Vienna, Austria; 4Parc Sanitari Sant Joan de Déu, Fundació Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Barcelona, Spain; 5Eli Lilly and Company, Indianapolis, IN, USA; 6Università di Roma, “Sapienza,” Rome, ItalyBackground: Patients with major depressive disorder (MDD may suffer from concomitant pain symptoms. The aim of this study is to determine whether the presence of painful physical symptoms (PPS influences quality of life when taking into account baseline depression severity.Methods: Patients with a new or first episode of MDD (n = 909 were enrolled in a 3-month prospective observational study in East Asia. The Hamilton Depression Rating Scale, Clinical Global Impression-Severity score, Somatic Symptom Inventory, and EuroQoL questionnaire-5 Dimensions (EQ-5D and EQ-Visual Analogue Scale (EQ-VAS were assessed at baseline and 3 months’ follow-up. The presence of PPS was defined as a mean score of ≥2 on the Somatic Symptom Inventory pain-related items. Regression analyses determined predictors of quality of life at 3 months, adjusting for age, sex, depressive symptoms, overall severity, and quality of life at baseline.Results: PPS were present (PPS+ at baseline in 52% of patients. During the 3-month follow-up, EQ-VAS scores improved from 47.7 (standard deviation [SD] 20.6 to 72.5 (SD 20.4, and EQ-5D improved from 0.48 (SD 0.34 to 0.80 (SD 0.26. At 3 months, mean EQ-VAS was 66.4 (SD 21.2 for baseline PPS+ patients versus 78.5 (SD 17.6 for baseline PPS- patients, and mean EQ-5D was 0.71 (SD 0.29 versus 0.89 (SD 0.18. PPS+ at baseline was a significant predictor of quality of life at 3 months after adjusting for sociodemographic and baseline clinical variables

  14. Comparative efficacy of selective serotonin reuptake inhibitors (SSRI) in treating major depressive disorder: a protocol for network meta-analysis of randomised controlled trials.

    Science.gov (United States)

    Jia, Yongliang; Zhu, Hongmei; Leung, Siu-Wai

    2016-06-07

    There have been inconsistent findings from randomised controlled trials (RCTs) and systematic reviews on the efficacies of selective serotonin reuptake inhibitors (SSRIs) as the first-line treatment of major depressive disorder (MDD). Besides inconsistencies among randomised controlled trials (RCTs), their risks of bias and evidence grading have seldom been evaluated in meta-analysis. This study aims to compare the efficacy of SSRIs by conducting a Bayesian network meta-analysis, which will be the most comprehensive evaluation of evidence to resolve the inconsistency among previous studies. SSRIs including citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline and vilazodone have been selected. Systematic database searching and screening will be conducted for the RCTs on drug treatment of patients with MDD according to pre-specified search strategies and selection criteria. PubMed, the Cochrane Library, EMBASE, ScienceDirect, the US Food and Drug Administration Website, ClinicalTrial.gov and WHO Clinical Trials will be searched. Outcome data including Hamilton Depression Rating Scale (HDRS), Montgomery-Åsberg Depression Rating Scale (MADRS) and Clinical Global Impression (CGI) from eligible RCTs will be extracted. The outcomes will be analysed as ORs and mean differences under a random-effects model. A Bayesian network meta-analysis will be conducted with WinBUGS software, to compare the efficacies of SSRIs. Subgroup and sensitivity analysis will be performed to explain the study heterogeneity and evaluate the robustness of the results. Meta-regression analysis will be conducted to determine the possible factors affecting the efficacy outcomes. The Cochrane risk of bias assessment tool will be used to assess the RCT quality, and the Grading of Recommendation, Assessment, Development and Evaluation will be used to assess the strength of evidence from the meta-analysis. No ethical approval is required because this study includes neither

  15. N-Acetylcysteine in depressive symptoms and functionality: a systematic review and meta-analysis.

    Science.gov (United States)

    Fernandes, Brisa S; Dean, Olivia M; Dodd, Seetal; Malhi, Gin S; Berk, Michael

    2016-04-01

    To assess the utility of N-acetylcysteine administration for depressive symptoms in subjects with psychiatric conditions using a systematic review and meta-analysis. A computerized literature search was conducted in MEDLINE, Embase, the Cochrane Library, SciELO, PsycINFO, Scopus, and Web of Knowledge. No year or country restrictions were used. The Boolean terms used for the electronic database search were (NAC OR N-acetylcysteine OR acetylcysteine) AND (depression OR depressive OR depressed) AND (trial). The last search was performed in November 2014. The literature was searched for double-blind, randomized, placebo-controlled trials using N-acetylcysteine for depressive symptoms regardless of the main psychiatric condition. Using keywords and cross-referenced bibliographies, 38 studies were identified and examined in depth. Of those, 33 articles were rejected because inclusion criteria were not met. Finally, 5 studies were included. Data were extracted independently by 2 investigators. The primary outcome measure was change in depressive symptoms. Functionality, quality of life, and manic and anxiety symptoms were also examined. A full review and meta-analysis were performed. Standardized mean differences (SMDs) and odds ratios (ORs) with 95% CIs were calculated. Five studies fulfilled our inclusion criteria for the meta-analysis, providing data on 574 participants, of whom 291 were randomized to receive N-acetylcysteine and 283 to placebo. The follow-up varied from 12 to 24 weeks. Two studies included subjects with bipolar disorder and current depressive symptoms, 1 included subjects with MDD in a current depressive episode, and 2 included subjects with depressive symptoms in the context of other psychiatric conditions (1 trichotillomania and 1 heavy smoking). Treatment with N-acetylcysteine improved depressive symptoms as assessed by Montgomery-Asberg Depression Rating Scale and Hamilton Depression Rating Scale when compared to placebo (SMD = 0.37; 95% CI = 0

  16. The prevalence and illness characteristics of DSM-5-defined "mixed feature specifier" in adults with major depressive disorder and bipolar disorder: Results from the International Mood Disorders Collaborative Project.

    Science.gov (United States)

    McIntyre, Roger S; Soczynska, Joanna K; Cha, Danielle S; Woldeyohannes, Hanna O; Dale, Roman S; Alsuwaidan, Mohammad T; Gallaugher, Laura Ashley; Mansur, Rodrigo B; Muzina, David J; Carvalho, Andre; Kennedy, Sidney H

    2015-02-01

    A substantial proportion of individuals with mood disorders present with sub-syndromal hypo/manic features. The objective of this analysis was to evaluate the prevalence and illness characteristics of the Diagnostic and Statistical Manual Version-5 (DSM-5) - defined mixed features specifier (MFS) in adults with major depressive disorder (MDD) and bipolar disorder (BD). Data from participants who met criteria for a current mood episode as part of MDD (n=506) or BD (BD-I: n=216, BD-II: n=130) were included in this post-hoc analysis. All participants were enrolled in the International Mood Disorders Collaborative Project (IMDCP): a collaborative research platform at the Mood Disorders Psychopharmacology Unit, University of Toronto and the Cleveland Clinic, Cleveland, Ohio. Mixed features specifier was operationalized as a score ≥ 1 on 3 or more select items on the Young Mania Rating Scale (YMRS) or ≥ 1 on 3 select items of the Montgomery Åsberg Depression Rating Scale (MADRS) or Hamilton Depression Rating Scale (HAMD-17) during an index major depressive episode (MDE) or hypo/manic episode, respectively. A total of 26.0% (n=149), 34.0% (n=65), and 33.8% (n=49) of individuals met criteria for MFS during an index MDE as part of MDD, BD-I and BD-II, respectively. Mixed features specifier during a hypo/manic episode was identified in 20.4% (n=52) and 5.1% (n=8) in BD-I and BD-II participants, respectively. Individuals with MDE-MFS as part of BD or MDD exhibited a more severe depressive phenotype (p=0.0002 and pdefined MFS is common during an MDE as part of MDD and BD. The presence of MFS identifies a subgroup of individuals with greater illness complexity and possibly a higher rate of cardiovascular comorbidity. The results herein underscore the common occurrence of MFS in adults with either BD or MDD. Moreover, the results of our analysis indicate that adults with mood disorders and MFS have distinct clinical characteristics and comorbidity patterns. Copyright

  17. Single i.v. ketamine augmentation of newly initiated escitalopram for major depression: results from a randomized, placebo-controlled 4-week study.

    Science.gov (United States)

    Hu, Y-D; Xiang, Y-T; Fang, J-X; Zu, S; Sha, S; Shi, H; Ungvari, G S; Correll, C U; Chiu, H F K; Xue, Y; Tian, T-F; Wu, A-S; Ma, X; Wang, G

    2016-02-01

    While oral antidepressants reach efficacy after weeks, single-dose intravenous (i.v.) ketamine has rapid, yet time-limited antidepressant effects. We aimed to determine the efficacy and safety of single-dose i.v. ketamine augmentation of escitalopram in major depressive disorder (MDD). Thirty outpatients with severe MDD (17-item Hamilton Rating Scale for Depression total score ⩾ 24) were randomized to 4 weeks double-blind treatment with escitalopram 10 mg/day+single-dose i.v. ketamine (0.5 mg/kg over 40 min) or escitalopram 10 mg/day + placebo (0.9% i.v. saline). Depressive symptoms were measured using the Montgomery-Asberg Depression Rating Scale (MADRS) and the Quick Inventory of Depressive Symptomatology - Self-Report (QIDS-SR). Suicidal ideation was evaluated with the QIDS-SR item 12. Adverse psychopathological effects were measured with the Brief Psychiatric Rating Scale (BPRS)-positive symptoms, Young Mania Rating Scale (YMRS) and Clinician Administered Dissociative States Scale (CADSS). Patients were assessed at baseline, 1, 2, 4, 24 and 72 h and 7, 14, 21 and 28 days. Time to response (⩾ 50% MADRS score reduction) was the primary outcome. By 4 weeks, more escitalopram + ketamine-treated than escitalopram + placebo-treated patients responded (92.3% v. 57.1%, p = 0.04) and remitted (76.9% v. 14.3%, p = 0.001), with significantly shorter time to response [hazard ratio (HR) 0.04, 95% confidence interval (CI) 0.01-0.22, p escitalopram + placebo, escitalopram + ketamine was associated with significantly lower MADRS scores from 2 h to 2 weeks [(peak = 3 days-2 weeks; effect size (ES) = 1.08-1.18)], QIDS-SR scores from 2 h to 2 weeks (maximum ES = 1.27), and QIDS-SR suicidality from 2 to 72 h (maximum ES = 2.24). Only YMRS scores increased significantly with ketamine augmentation (1 and 2 h), without significant BPRS or CADSS elevation. Single-dose i.v. ketamine augmentation of escitalopram was safe and effective in severe MDD, holding promise for speeding up

  18. THE РERSONALITY PROFILE OF PATIENTS WITH EARLY MANIFESTATIONS OF PARKINSON'S DISEASE

    Directory of Open Access Journals (Sweden)

    R. R. Bogdanov

    2016-01-01

    Full Text Available Background: Mental disorders that sometimes may precede motor dysfunction have an important value in Parkinson's disease, especially at its earlier stages. Personality characteristics of patients with Parkinson's disease have not been studied enough and require a  detailed assessment, because it is a  major factor contributing to treatment efficacy. Aim: To assess personality profiles of patients with early stages of Parkinson's disease and an impact of a dopamine receptor agonist on the personality profile. Materials and methods: We assessed 33 treatment-naïve patients with early symptoms of Parkinson's disease (Hoehn-Yahr stage I and II. The following scales were used before treatment and at 1, 3 and 6 months of treatment with pramipexol: for motor disorders (UPDRS, Unified Parkinson's Disease Rating Scale, depressive disorders (MADRS, Montgomery Asberg Depression Rating Scale and anxiety disorders (HARS, Hamilton Anxiety Rating Scale, as well as personality profile (MMPI, Minnesota Multiphasic Personality Inventory. Results: The personality profile assessed by MMPI in patients with early stage Parkinson's disease was characterized by highest T scores on scales 2 (pessimism (74 [64; 86], 1 (neurotic excess control (67 [63; 74], 3  (emotional instability (64 [56; 70], 7 (anxiousness (63 [52; 70], 8 (autism (64 [58; 74], 0  (introversion (63 [59; 66]. This indicates basic pathopsychological characteristics of patients with early stages of the disease. In particular, their emotional sphere demonstrated anxiety- and depression-related affective disorders. Their personality structure was characterized by dysthymic, anxious, rigid and explosive traits, and susceptibility to hypochondriasis. With a background of a dramatic motivational conflict, frustration of high-level need in self-actualization and recognition due to a chronic disease with motor dysfunction triggered a depressive response type. Pharmacological treatment with

  19. Depression Case Finding in Individuals with Dementia: A Systematic Review and Meta-Analysis.

    Science.gov (United States)

    Goodarzi, Zahra S; Mele, Bria S; Roberts, Derek J; Holroyd-Leduc, Jayna

    2017-05-01

    To compare the diagnostic accuracy of depression case finding tools with a criterion standard in the outpatient setting among adults with dementia. Systematic review and meta-analysis. Studies of older outpatients with dementia. Elderly outpatients (clinic and long-term care) with dementia (N = 3,035). Prevalence of major depression and diagnostic accuracy measures including sensitivity, specificity, and likelihood ratios. From the 11,539 citations, 20 studies were included for qualitative synthesis and 15 for a meta-analysis. Tools included were the Montgomery Åsberg Depression Rating Scale, Cornell Scale for Depression in Dementia (CSDD), Geriatric Depression Scale (GDS), Center for Epidemiologic Studies Depression Scale (CES-D), Hamilton Depression Rating Scale (HDRS), Single Question, Nijmegen Observer-Rated Depression Scale, and Even Briefer Assessment Scale-Depression. The pooled prevalence of depression in individuals with dementia was 30.3% (95% CI = 22.1-38.5). The average age was 75.2 (95% CI = 71.7-78.7), and mean Mini-Mental State Examination scores ranged from 11.2 to 24. The diagnostic accuracy of the individual tools was pooled for the best-reported cutoffs and for each cutoff, if available. The CSDD had a sensitivity of 0.84 (95% CI = 0.73-0.91) and a specificity of 0.80 (95% CI = 0.65-0.90), the 30-item GDS (GDS-30) had a sensitivity of 0.62 (95% CI = 0.45-0.76) and a specificity 0.81 (95% CI = 0.75-0.85), and the HDRS had a sensitivity of 0.86 (95% CI = 0.63-0.96) and a specificity of 0.84 (95% CI = 0.76-0.90). Summary statistics for all tools across best-reported cutoffs had significant heterogeneity. There are many validated tools for the detection of depression in individuals with dementia. Tools that incorporate a physician interview with patient and collateral histories, the CSDD and HDRS, have higher sensitivities, which would ensure fewer false-negatives. © 2017, Copyright the Authors Journal compilation © 2017, The American Geriatrics

  20. Adjunctive treatment with transcranial magnetic stimulation in treatment resistant depression: a randomized, double-blind, sham-controlled study

    Directory of Open Access Journals (Sweden)

    Qiang LIU

    2011-02-01

    Full Text Available Background: High-frequency repetitive transcranial magnetic stimulation (rTMS to the left prefrontal cortex is a promising antidepressant treatment but the appropriate duration of treatment andits effect on cognitive symptoms in treatment resistant patients is uncertain.Hypotheis: Patients with treatment resistant depression on standard antidepressant medication who receive four weeks of adjunctive treatment with high-frequency rTMS to the left prefrontal cortex will have better clinical outcomes and better cognitive functioning than those who receive sham rTMS treatments.Methods: Thirty patients with treatment resistant depression (defined as failure to respond to two or more antidepressants of different classes administered for at least 6 weeks at or above two-thirds of the recommended maximum dose receiving selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors wererandomly assigned to receive adjundive treatment with either real rTMS (n=15 or sham rTMS (n=15 5 times a week for 4 conseculive weeks. Blinded pre-post evaluations were conducted using the 17-item Hamilton Depression Rating Scale (HAMD, the Montgomery-Asberg Depression Rating Scale (MADRS, the severity of illness measure from the Clinical Global Impression Rating scale(CGI-S, the Wechsler Adult Intelligence ScaIe (WAIS, the Wechsler Memory Scale (WMS, and the Wisconsjn Card Sorting Test(WC5T.Results:14 subjects from each group completed the study. There was no significant difference in the HAMD total scores between the two groups after 2 weeks of treatment but after 4 weeks of treatment the mean percentage drop in the HAMD total score was significantly greater in the real rTMS group (49%, SD=19% than in the sham rTMS group(29%, SD=25%, with a mean difference of 20% [95%CI=3%-37%;t26=2.42; P=0.023]. At 4 weeks the mean (SD reduction in the MADRS total score was also greater in the real rTMS group [47%(23% vs 16%(40

  1. Non-Noether symmetries of Hamiltonian systems with conformable fractional derivatives

    International Nuclear Information System (INIS)

    Wang Lin-Li; Fu Jing-Li

    2016-01-01

    In this paper, we present the fractional Hamilton’s canonical equations and the fractional non-Noether symmetry of Hamilton systems by the conformable fractional derivative. Firstly, the exchanging relationship between isochronous variation and fractional derivatives, and the fractional Hamilton principle of the system under this fractional derivative are proposed. Secondly, the fractional Hamilton’s canonical equations of Hamilton systems based on the Hamilton principle are established. Thirdly, the fractional non-Noether symmetries, non-Noether theorem and non-Noether conserved quantities for the Hamilton systems with the conformable fractional derivatives are obtained. Finally, an example is given to illustrate the results. (paper)

  2. La función característica de punto de Hamilton y la función de tiempos de difracción de la sísmica geométrica en la migración con amplitudes verdaderas

    Directory of Open Access Journals (Sweden)

    Montes Vides Luis Alfredo

    2000-08-01

    Full Text Available

    Using the paraxial ray theory in the second order approximation of the traveltimes, we can estimate the traveltime function of a wavefront coming from a reflector, and in consequence calculate the diffraction traveltime function associated with a diffractor point located on the reflector. The numerical knowledge of those two functions makes possible a process to migrate stacked sections in time, process which generate images of seismic sections with true amplitudes. The restitution of the wave amplitude is made using an operator which depends of the parameters of the traveltime function A differentiation filter is applied to the migrated sections in order to obtain the original wave phase. Layered models with smooth interfaces are used.

    Usando la teoría del rayo paraxial en la aproximación de segundo de los tiempos de tránsito, podemos estimar la función de tiempos de tránsito asociada a un frente de onda proveniente de un reflector, y en consecuencia calcular la función de tiempos de difracción de un frente de onda generado por un punto difractor situado en el reflector. EI conocimiento numérico de estas funciones hace posible un proceso de migración en tiempo de secciones apiladas que generan imágenes de secciones sísmicas con amplitudes verdaderas. La restitución de la amplitud de la onda se realiza mediante un operador que es función de los parametros de la función tiempo de transito. A las secciones migradas se les aplica un filtro de diferenciación para obtener las fases iniciales del campo de onda. Se usan modelos de capas separadas por interfaces suaves.

  3. Monetary valuation of salinity impacts and microbial pollution in the Olifants Water Management Area, South Africa

    CSIR Research Space (South Africa)

    De Lange, Willem J

    2012-04-01

    Full Text Available , salmonellosis and typhoid fever (Department of Water Affairs and Forestry, 2001). A direct functional relationship exists between dysfunctional water and sanitation systems and a high risk of waterborne disease (Hinrichsen et al., 1997, Montgomery...

  4. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Services The Latino AIDS Agenda National Foundation for Women Legislators (NFWL) Educational Institutions: Florida International University Montgomery College Center for the Advancement of Distance Education University of Southern California, Maternal Child & Adolescent Program ...

  5. Most Recent Sampling Results for Annex III Building

    Science.gov (United States)

    Contains email from Scott Miller, US EPA to Scott Kramer. Subject: Most Recent Sampling Results for Annex III Building. (2:52 PM) and Gore(TM) Surveys Analytical Results U.S. Geological Survey, Montgomery, AL.

  6. Drugs + HIV, Learn the Link

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    Full Text Available ... for Women Legislators (NFWL) Educational Institutions: Florida International University Montgomery College Center for the Advancement of Distance Education University of Southern California, Maternal Child & Adolescent Program University ...

  7. Quantum Groupoids Acting on Semiprime Algebras

    Directory of Open Access Journals (Sweden)

    Inês Borges

    2011-01-01

    Full Text Available Following Linchenko and Montgomery's arguments we show that the smash product of an involutive weak Hopf algebra and a semiprime module algebra, satisfying a polynomial identity, is semiprime.

  8. OCA Code Enforcement

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    Montgomery County of Maryland — The Office of the County Attorney (OCA) processes Code Violation Citations issued by County agencies. The citations can be viewed by issued department, issued date...

  9. Co-Occurring Disorders

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    ... the mental health field. Alcohol and Drug Abuse, Addiction and Co-occurring Disorders: Co-occurring Disorders and ... 500 Montgomery Street, Suite 820 Alexandria, VA 22314 Phone (703) 684.7722 Toll Free (800) 969.6642 ...

  10. Drugs + HIV, Learn the Link

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    Full Text Available ... groups of young people, guiding the use of technology, the discussion between friends, and the importance of ... Montgomery College Center for the Advancement of Distance Education University of Southern California, Maternal Child & Adolescent Program ...

  11. Genetics Home Reference: Potocki-Shaffer syndrome

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    ... PubMed Central Montgomery ND, Turcott CM, Tepperberg JH, McDonald MT, Aylsworth AS. A 137-kb deletion within ... 10 All Bulletins Features What is direct-to-consumer genetic testing? What are genome editing and CRISPR- ...

  12. 76 FR 70386 - Proposed Flood Elevation Determinations

    Science.gov (United States)

    2011-11-14

    ..., Alabama, and Incorporated Areas Audubon Ditch At the upstream side of +185 +184 City of Montgomery. Norman... available for inspection at 36535 Green Street, New Baltimore, MI 48047. Township of Chesterfield Maps are...

  13. Product Purchases by DLC

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    Montgomery County of Maryland — This dataset contains a list of items in case units by category and supplier that have been purchased by the Department of Liquor Control in the past month. Update...

  14. Airway Clearance Techniques (ACTs)

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    Full Text Available ... Dr. William Skach Paul di Sant’Agnese Distinguished Scientific Achievement Award Quality Care Awards Richard C Talamo ... clinical trial that may be right for you. Search Trials CFF Homepage Cystic Fibrosis Foundation 4550 Montgomery ...

  15. Floodplain District Permit

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    Montgomery County of Maryland — The purpose of a Floodplain District Permit (FPDP) is to control floodplain development in order to protect persons and property from danger and destruction and to...

  16. Drugs + HIV, Learn the Link

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    Full Text Available ... Foundation for Women Legislators (NFWL) Educational Institutions: Florida International University Montgomery College Center for the Advancement of Distance Education University of Southern California, Maternal Child & Adolescent Program ...

  17. Water Quality Protection Charges

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    Montgomery County of Maryland — The Water Quality Protection Charge (WQPC) is a line item on your property tax bill. WQPC funds many of the County's clean water initiatives including: • Restoration...

  18. Real Property Tax Rates

    Data.gov (United States)

    Montgomery County of Maryland — The Levy Year 2012 real property tax rate dataset reflects all the rates per $100 set each year by the County Council. These rates are applied to the assessed value...

  19. Agricultural Producer Certificates

    Data.gov (United States)

    Montgomery County of Maryland — A Certified Agricultural Producer, or representative thereof, is an individual who wishes to sell regionally-grown products in the public right-of-way. A Certified...

  20. Capital Improvement Program (CIP) Project Status

    Data.gov (United States)

    Montgomery County of Maryland — This dataset includes pertinent information relating to a capital project’s status administered by the Department of Transportation and the Department of General...

  1. Building Homes, Building Careers.

    Science.gov (United States)

    Cohn, Meredith

    1987-01-01

    The Construction Trades Foundation, a nonprofit corporation of business, industry, and school leaders, provides high school students in Montgomery County, Maryland, with unique hands-on experiences in construction, home design, marketing, public relations, and other fields. (SK)

  2. Site Specific Vendor's License

    Data.gov (United States)

    Montgomery County of Maryland — This dataset contains information of a site-specific vendor's license which is required if an individual sells or offers to sell goods or services from a stationary...

  3. Stormwater Management Concept Information

    Data.gov (United States)

    Montgomery County of Maryland — A stormwater management concept is a statement or drawing, or both, describing the manner in which stormwater runoff from a proposed development will be controlled...

  4. 77 FR 65044 - Pennsylvania Disaster #PA-00054

    Science.gov (United States)

    2012-10-24

    ... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13346 and 13347] Pennsylvania Disaster PA... Administrative declaration of a disaster for the Commonwealth of Pennsylvania dated 10/18/2012. Incident... adversely affected by the disaster: Primary Counties: Montgomery. Contiguous Counties: Pennsylvania: Berks...

  5. 75 FR 71486 - Pennsylvania Disaster # PA-00035

    Science.gov (United States)

    2010-11-23

    ... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 12389 and 12390] Pennsylvania Disaster PA... Administrative declaration of a disaster for the Commonwealth of Pennsylvania dated 11/15/2010. Incident: Severe... the disaster: Primary Counties: Delaware. Contiguous Counties: Pennsylvania: Chester, Montgomery...

  6. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Advocates Against AIDS The Women’s Collective K.I. Services The Latino AIDS Agenda National Foundation for Women Legislators (NFWL) Educational Institutions: Florida International University Montgomery College Center for the Advancement of Distance ...

  7. Softball Complex

    Science.gov (United States)

    Ellis, Jim

    1977-01-01

    The Parks and Recreation Department of Montgomery, Alabama, has developed a five-field softball complex as part of a growing community park with facilities for camping, golf, aquatics, tennis, and picnicking. (MJB)

  8. Operation Market-Garden: Ultra Intelligence Ignored

    National Research Council Canada - National Science Library

    Jeffson, Joel

    2002-01-01

    .... Is this really the case? Operation Market-Garden, the plan envisioned by Field Marshal Montgomery, would open the gate into Germany and simultaneously force General Eisenhower to abandon his broad-front strategy in favor...

  9. Updating ARI Educational Benefits Usage Data Bases for Army Regular, Reserve, and Guard: 2005 - 2006

    National Research Council Canada - National Science Library

    Young, Winnie

    2007-01-01

    This report describes the updating of ARI's educational benefits usage database with Montgomery GI Bill and Army College Fund data for Army Regular, Reserve, and Guard components over the 2005 and 2006 period...

  10. Airway Clearance Techniques (ACTs)

    Medline Plus

    Full Text Available Skip to Main Content Skip to Footer CFF Homepage Menu Search What Is CF? X close ABOUT ... may be right for you. Search Trials CFF Homepage Cystic Fibrosis Foundation 4550 Montgomery Ave. Suite 1100 ...

  11. 78 FR 44187 - New York Disaster # NY-00136

    Science.gov (United States)

    2013-07-23

    ...; Herkimer; Madison; Montgomery; Niagara; Oneida; Otsego; Warren. The Interest Rates are: Percent For... for economic injury is 13668B (Catalog of Federal Domestic Assistance Numbers 59002 and 59008). James...

  12. Alabama Cooperative Extension System - ACES.edu

    Science.gov (United States)

    Marshall Mobile Monroe Montgomery Morgan Perry Pickens Pike Randolph Russell Shelby St. Clair Sumter Marengo Tuscaloosa Greene Pickens Sumter Conecuh Escambia Monroe Clarke Choctaw Washington Baldwin Mobile Office Communications & Marketing Information Technology ACES Publications & Store 4-H &

  13. Kaasaegseid maailmavaateid kohtulaua ees / Ants Oras

    Index Scriptorium Estoniae

    Oras, Ants

    2003-01-01

    Montgomery Belgioni raamatust "Our present philosophy of life", mis tutvustab Bernard Shaw', André Gide'i, Sigmund Freudi ja Bertrand Russelli filosoofilisi teooriaid. Varem ilmunud: "Looming", 1931, nr. 6, lk. 646-651

  14. Real Property Tax - 2017

    Data.gov (United States)

    Montgomery County of Maryland — This data represents all of the County’s residential real estate properties and all of the associated tax charges and credits with that property processed at the...

  15. How Loud Is Too Loud? | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... visit www.noisyplanet.nidcd.nih.gov The High Cost of Noise Exposure Kurt Evers of Montgomery Village, ... too. Doctors, parents, and educators worry about portable music players and other noisy gadgets damaging hearing in ...

  16. Drugs + HIV, Learn the Link

    Medline Plus

    Full Text Available ... Adolescent Psychiatry (AACAP) The United Negro College Fund, Special Programs Latino Commission on AIDS Azteca America Foundation/ ... Montgomery College Center for the Advancement of Distance Education University of Southern California, Maternal Child & Adolescent Program ...

  17. 75 FR 4415 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2010-01-27

    ... comments should be submitted by Dated: February 11, 2010. J. Paul Loether, Chief, National Register of... Building, 125 Cherry St., Buffalo, 10000027 Montgomery County Chalmers Knitting Mills, 21-41 Bridge St...

  18. 40 CFR 52.1683 - Control strategy: Ozone.

    Science.gov (United States)

    2010-07-01

    ... not apply to these areas. (i) Albany-Schenectady-Troy (consisting of Albany, Greene, Montgomery... determination shall no longer apply in the area where the violation occurs. (i) Albany-Schenectady-Troy...

  19. Floodplain Study

    Data.gov (United States)

    Montgomery County of Maryland — The purpose of a floodplain study is to establish the 100-year floodplain limits within or near a development in order to preserve the natural resources within the...

  20. An easy and low cost option for economic statistical process control ...

    African Journals Online (AJOL)

    a large number of nonconforming products are manufactured. ... size, n, sampling interval, h, and control limit parameter, k, that minimize the ...... [11] Montgomery DC, 2001, Introduction to statistical quality control, 4th Edition, John Wiley, New.