WorldWideScience

Sample records for halo machine induced

  1. A multi-machine scaling of halo current rotation

    Science.gov (United States)

    Myers, C. E.; Eidietis, N. W.; Gerasimov, S. N.; Gerhardt, S. P.; Granetz, R. S.; Hender, T. C.; Pautasso, G.; Contributors, JET

    2018-01-01

    Halo currents generated during unmitigated tokamak disruptions are known to develop rotating asymmetric features that are of great concern to ITER because they can dynamically amplify the mechanical stresses on the machine. This paper presents a multi-machine analysis of these phenomena. More specifically, data from C-Mod, NSTX, ASDEX Upgrade, DIII-D, and JET are used to develop empirical scalings of three key quantities: (1) the machine-specific minimum current quench time, \

  2. HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins.

    Science.gov (United States)

    Buckley, Dennis L; Raina, Kanak; Darricarrere, Nicole; Hines, John; Gustafson, Jeffrey L; Smith, Ian E; Miah, Afjal H; Harling, John D; Crews, Craig M

    2015-08-21

    Small molecule-induced protein degradation is an attractive strategy for the development of chemical probes. One method for inducing targeted protein degradation involves the use of PROTACs, heterobifunctional molecules that can recruit specific E3 ligases to a desired protein of interest. PROTACs have been successfully used to degrade numerous proteins in cells, but the peptidic E3 ligase ligands used in previous PROTACs have hindered their development into more mature chemical probes or therapeutics. We report the design of a novel class of PROTACs that incorporate small molecule VHL ligands to successfully degrade HaloTag7 fusion proteins. These HaloPROTACs will inspire the development of future PROTACs with more drug-like properties. Additionally, these HaloPROTACs are useful chemical genetic tools, due to their ability to chemically knock down widely used HaloTag7 fusion proteins in a general fashion.

  3. Artificial halos

    Science.gov (United States)

    Selmke, Markus

    2015-09-01

    Judged by their frequency and beauty, ice halos easily rival rainbows as a prominent atmospheric optics phenomenon. This article presents experimental halo demonstrations of varying complexity. Using a single commercially available hexagonal glass prism, a variety of artificial halos can be simulated. The experiments include laser beam path analysis, a modified classic spinning prism experiment, and a novel Monte-Carlo machine for three-dimensional rotations. Each of these experiments emulates different conditions of certain halo displays, and in combination, they allow a thorough understanding of these striking phenomena.

  4. Machine-induced Background Simulation Studies for LHC Run 1, Run 2 and HL-LHC

    CERN Document Server

    Kwee-Hinzmann, Regina; Bruce, Roderik; Cerutti, Francesco; Esposito, Luigi Salvatore; Gibson, Stephen; Lechner, Anton; Garcia Morales, Hector; Yin Vallgren, Christina

    2017-01-01

    The study of machine-induced background to the experiments is vital for several reasons. Too much background can be an issue for operation and the difficult part is to judge when exactly “too much” is attained. It is a complex topic as experiments are directly or indirectly affected by conditions all around the LHC ring e.g. collimation settings and vacuum quality. A detailed study of background can also help understanding the machine better to identify potential issues and complemented by dedicated machine tests. Finally such a study is relevant for the experiments to analyse the characteristics of machine background to make sure not to count it into a new physics signal. This report summarises simulation results of three background sources, local beam-gas, beam-halo from the betatron collimation in IR7 and for the first time beam-halo from momentum collimation in IR3. Two of the most dominant sources, local beam-gas and betatron halo, have been systematically studied for LHC Run 1 and Run 2 cases, and ...

  5. Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins.

    Science.gov (United States)

    Neklesa, Taavi K; Tae, Hyun Seop; Schneekloth, Ashley R; Stulberg, Michael J; Corson, Timothy W; Sundberg, Thomas B; Raina, Kanak; Holley, Scott A; Crews, Craig M

    2011-07-03

    The ability to regulate any protein of interest in living systems with small molecules remains a challenge. We hypothesized that appending a hydrophobic moiety to the surface of a protein would mimic the partially denatured state of the protein, thus engaging the cellular quality control machinery to induce its proteasomal degradation. We designed and synthesized bifunctional small molecules to bind a bacterial dehalogenase (the HaloTag protein) and present a hydrophobic group on its surface. Hydrophobic tagging of the HaloTag protein with an adamantyl moiety induced the degradation of cytosolic, isoprenylated and transmembrane HaloTag fusion proteins in cell culture. We demonstrated the in vivo utility of hydrophobic tagging by degrading proteins expressed in zebrafish embryos and by inhibiting Hras1(G12V)-driven tumor progression in mice. Therefore, hydrophobic tagging of HaloTag fusion proteins affords small-molecule control over any protein of interest, making it an ideal system for validating potential drug targets in disease models.

  6. Small-Molecule Hydrophobic Tagging Induced Degradation of HaloTag Fusion Proteins

    Science.gov (United States)

    Neklesa, Taavi K.; Tae, Hyun Seop; Schneekloth, Ashley R.; Stulberg, Michael J.; Corson, Timothy W.; Sundberg, Thomas B.; Raina, Kanak; Holley, Scott A.; Crews, Craig M.

    2011-01-01

    The ability to regulate any protein of interest in living systems with small molecules remains a challenge. We hypothesized that appending a hydrophobic moiety to the surface of a protein would mimic the partially denatured state of the protein, thus engaging the cellular quality control machinery to induce its proteasomal degradation. We designed and synthesized bifunctional small molecules that bind a bacterial dehalogenase (HaloTag protein) and present a hydrophobic group on its surface. Remarkably, hydrophobic tagging of the HaloTag protein with an adamantyl moiety induced the degradation of cytosolic, isoprenylated, and transmembrane fusion proteins in cell culture. We demonstrated the in vivo utility of hydrophobic tagging by degrading proteins expressed in zebrafish embryos and by inhibiting RasG12V-driven tumor progression in mice. Therefore, hydrophobic tagging of HaloTag fusion proteins affords small molecule control over any protein of interest, making it an ideal system for validating potential drug targets in disease models. PMID:21725302

  7. Assessment of pheromone production and response in fission yeast by a halo test of induced sporulation

    DEFF Research Database (Denmark)

    Egel, R; Willer, M; Kjaerulff, S

    1994-01-01

    We describe a rapid, sensitive and semi-quantitative plate assay for monitoring pheromone activity in the fission yeast Schizosaccharomyces pombe. It is based on the observation that meiosis requires stimulation by pheromone and exploits diploid strains that will only sporulate after addition...... of exogenous pheromone. The tester strains are heterozygous for mating type, are non-switching, and are mutated in one of the early subfunctions (either mat1-Mc or mat1-Pc), so that meiosis is only induced after exposure to exogenous pheromone (M-factor or P-factor, respectively). Pheromone activity...... is assessed as an iodine-positive halo of sporulation surrounding the pheromone source, and the width of the halo is related to the amount of pheromone being produced. The assay is sufficiently sensitive to monitor the low amount of M-factor produced by an M mam1 strain, and its sensitivity towards P...

  8. Tracking the LHC halo

    CERN Document Server

    Antonella Del Rosso

    2015-01-01

    In the LHC, beams of 25-ns-spaced proton bunches travel at almost the speed of light and pass through many different devices installed along the ring that monitor their properties. During their whirling motion, beam particles might interact with the collimation instrumentation or with residual gas in the vacuum chambers and this creates the beam halo – an annoying source of background for the physics data. Newly installed CMS sub-detectors are now able to monitor it.   The Beam Halo Monitors (BHM) are installed around the CMS rotating shielding. The BHM are designed and built by University of Minnesota, CERN, Princeton University, INFN Bologna and the National Technical University of Athens. (Image: Andrea Manna). The Beam Halo Monitor (BHM) is a set of 20 Cherenkov radiators – 10-cm-long quartz crystals – installed at each end of the huge CMS detector. Their design goal is to measure the particles that can cause the so-called “machine-induced...

  9. Machine-Induced Showers Entering the Atlas and CMS Detectors in the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Bruce, R.; Assmann, R.W.; Boccone, V.; Burkhardt, H.; Cerutti, F.; Ferrari, A.; Huhtinen, M.; Kozanecki, W.; Levinsen, Y.; Mereghetti, A.; Rossi, A.; /CERN /FERMILAB /Karlsruhe U., ITP

    2011-09-12

    One source of experimental background in the LHC is showers induced by particles hitting the upstream collimators or particles that have been scattered on the residual gas. We estimate the flux and distribution of particles entering the ATLAS and CMS detectors through FLUKA simulations starting either in the tertiary collimators or with inelastic beam-gas interactions. Comparisons to MARS15 results are also presented. Our results can be used as a source term for further simulations of the machine-induced background in the experimental detectors. To ensure optimal performance of the LHC experimental detectors, it is important to understand the background, which can come fromseveral sources. In this article we discuss machine-induced background, caused either by nearby beam losses or interactions between beam particles and the residual gas inside the vacuum pipe. Beam losses outside the experimental interaction regions (IRs) are unavoidable during collider operation. The halo is continuously repopulated and has to be cleaned by the collimation system, so that the losses in the cold magnets are kept at a safe level. The collimation system is located in two dedicated insertions (IR3 and IR7) but a small leakage of secondary and tertiary halo is expected to escape. Some particles make it to the experimental IRs, where they are intercepted by tertiary collimators (TCTs) that are installed in order to protect the inner triplet magnets. Some parts of the induced high-energy shower can escape and propagate into the detectors. Another source of background is beam-gas interactions. Beam protons can scatter elastically or inelastically on residual gas molecules. If an inelastic interaction occurs close to the detector, it causes a shower that could reach the detector. Elastic interactions can scatter protons directly onto the TCTs without passing IR7, which has to be treated separately from the beam-halo losses discussed above. Machine-induced background can also originate

  10. Machine Induced Background with BCM1F 2015

    CERN Document Server

    CMS Collaboration

    2015-01-01

    BCM1F provides information on the condition of the beam and ensures that the inner detector occupancy is sufficiently low for data-taking. Measurements of the machine induced background for beam 1 (BKGD1) and beam 2 (BKGD2) are displayed in the CMS and LHC control room. The background data correlates the with collimator settings as well as with the vacuum pressure.

  11. Haloing in bimodal magnetic colloids: the role of field-induced phase separation.

    Science.gov (United States)

    Magnet, C; Kuzhir, P; Bossis, G; Meunier, A; Suloeva, L; Zubarev, A

    2012-07-01

    If a suspension of magnetic micrometer-sized and nanosized particles is subjected to a homogeneous magnetic field, the nanoparticles are attracted to the microparticles and form thick anisotropic halos (clouds) around them. Such clouds can hinder the approach of microparticles and result in effective repulsion between them [M. T. López-López, A. Yu. Zubarev, and G. Bossis, Soft Matter 6, 4346 (2010)]. In this paper, we present detailed experimental and theoretical studies of nanoparticle concentration profiles and of the equilibrium shapes of nanoparticle clouds around a single magnetized microsphere, taking into account interactions between nanoparticles. We show that at a strong enough magnetic field, the ensemble of nanoparticles experiences a gas-liquid phase transition such that a dense liquid phase is condensed around the magnetic poles of a microsphere while a dilute gas phase occupies the rest of the suspension volume. Nanoparticle accumulation around a microsphere is governed by two dimensionless parameters--the initial nanoparticle concentration (φ(0)) and the magnetic-to-thermal energy ratio (α)--and the three accumulation regimes are mapped onto a α-φ(0) phase diagram. Our local thermodynamic equilibrium approach gives a semiquantitative agreement with the experiments on the equilibrium shapes of nanoparticle clouds. The results of this work could be useful for the development of the bimodal magnetorheological fluids and of the magnetic separation technologies used in bioanalysis and water purification systems.

  12. Radiation-induced changes in nucleoid halo diameteres of aerobic and hypoxic SF-126 human brain tumor cells

    Energy Technology Data Exchange (ETDEWEB)

    Wang, J.; Basu, H.S.; Hu, L.; Feuerstein, B.G.; Deen, D.F. [Univ. of California, San Francisco, CA (United States)] [and others

    1995-02-01

    Nucleoid halo diameters were measured to assay changes in DNA supercoiling in human brain tumor cell line SF-126 after irradiation under aerobic or hypoxic conditions. In unirradiated aerobic cells, a typical propidium iodide titration curve showed that with increasing concentrations of propodium iodide, the halo diameter increased and then decreased with the unwinding and subsequent rewinding of DNA supercoils. In irradiated cells, the rewinding of DNA supercoils was inhibited, resulting in an increased halo diameter, in a radiation dose-dependent manner. To produce equal increases in halo diameter required about a threefold higher radiation dose in hypoxic cells than in aerobic cells. Quantitatively similiar differences in the radiation sensitivities of hypoxic and aerobic cells were demonstrated by a colony-forming efficiency assay. These findings suggest that the nucleoid halo assay may be used as a rapid measure of the inherent radiation sensitivity of human tumors. 22 refs., 5 figs.

  13. Weka machine learning for predicting the phospholipidosis inducing potential.

    Science.gov (United States)

    Ivanciuc, Ovidiu

    2008-01-01

    The drug discovery and development process is lengthy and expensive, and bringing a drug to market may take up to 18 years and may cost up to 2 billion $US. The extensive use of computer-assisted drug design techniques may considerably increase the chances of finding valuable drug candidates, thus decreasing the drug discovery time and costs. The most important computational approach is represented by structure-activity relationships that can discriminate between sets of chemicals that are active/inactive towards a certain biological receptor. An adverse effect of some cationic amphiphilic drugs is phospholipidosis that manifests as an intracellular accumulation of phospholipids and formation of concentric lamellar bodies. Here we present structure-activity relationships (SAR) computed with a wide variety of machine learning algorithms trained to identify drugs that have phospholipidosis inducing potential. All SAR models are developed with the machine learning software Weka, and include both classical algorithms, such as k-nearest neighbors and decision trees, as well as recently introduced methods, such as support vector machines and artificial immune systems. The best predictions are obtained with support vector machines, followed by perceptron artificial neural network, logistic regression, and k-nearest neighbors.

  14. Machine Induced Experimental Background Conditions in the LHC

    CERN Document Server

    Levinsen, Yngve Inntjore; Stapnes, Steinar

    2012-09-19

    The Large Hadron Collider set a new energy record for particle accelerators in late 2009, breaking the previous record held by Tevatron of 2 TeV collision energy. The LHC today operates at a collision energy of 7 TeV. With higher beam energy and intensity, measures have to be taken to ensure optimal experimental conditions and safety of the machine and detectors. Machine induced experimental background can severely reduce the quality of experimental triggers and track reconstruction. In a worst case, the radiation levels can be damaging for some of the subdetectors. The LHC is a particular challenge in this regard due to the vastly different operating conditions of the different experiments. The nominal luminosity varies by four orders of magnitude. The unprecedented stored beam energy and the amount of superconducting elements can make it challenging to protect the accelerator itself as well. In this work we have simulated and measured the machine induced background originating from various sources: the beam...

  15. Explanatory approach for evaluation of machine learning-induced knowledge.

    Science.gov (United States)

    Zorman, Milan; Verlic, M

    2009-01-01

    Progress in biomedical research has resulted in an explosive growth of data. Use of the world wide web for sharing data has opened up possibilities for exhaustive data mining analysis. Symbolic machine learning approaches used in data mining, especially ensemble approaches, produce large sets of patterns that need to be evaluated. Manual evaluation of all patterns by a human expert is almost impossible. We propose a new approach to the evaluation of machine learning-induced knowledge by introducing a pre-evaluation step. Pre-evaluation is the automatic evaluation of patterns obtained from the data mining phase, using text mining techniques and sentiment analysis. It is used as a filter for patterns according to the support found in online resources, such as publicly-available repositories of scientific papers and reports related to the problem. The domain expert can then more easily distinguish between patterns or rules that are potential candidates for new knowledge.

  16. Borromean halo, Tango halo, and halo isomers in atomic nuclei

    Science.gov (United States)

    Izosimov, Igor

    2016-01-01

    Structure of the ground and excited states in halo-like nuclei is discussed. Both the Borromean and tango halo types can be observed for n-p configurations of atomic nuclei.Structure of the halo may be different for the different levels and resonances in atomic nuclei. Isobar analog, double isobar analog, configuration, and double configuration states can simultaneously have n-n, n-p, and p-p halo components in their wave functions. When the halo structure of the excited state differs from that of the ground state, or the ground state has non-halo structure, the γ-transition from the excited state to the ground state can be essentially hindered, i.e. the formation of a specific type of isomers (halo isomers) becomes possible. B(Mγ) and B(Eγ) values for γ-transitions in 6,7,8Li, 8,9,10Be, 8,10,11B, 10,11,12,13,14C, 13,14,15,16,17N, 15,16,17,19O, and 17F are analyzed. Special attention is given to nuclei which ground state does not exhibit halo structure but the excited state (halo isomer) may have one.

  17. Structure Effects in Collisions Induced by Halo and Weakly Bound Nuclei Around the Coulomb Barrier

    CERN Document Server

    Scuderi, V; Torresi, D; Fisichella, M; Borge, M J G; Randisi, G; Milin, M; Figuera, P; Raabe, R; Di Pietro, A; Amorini, F; Fraile, L M; Vidal, A M; Rizzo, F; Zadro, M; Gomez-Camacho, J; Pellegriti, M G; Papa, M; Jeppesen, H; Santonocito, D; Sanchez, E M R; Acosta, L; Tengblad, O; Lattuada, M; Musumarra, A; Scalia, G

    2010-01-01

    In this contribution, results concerning different reaction channels for the collisions induced by the three Be isotopes, Be-9,Be-10,Be-11, on a Zn-64 target at energies around the Coulomb barrier will be presented. The experiments with the radioactive Be-10,Be-11 beams were performed at REX-ISOLDE (CERN) whereas the experiment with the stable weakly bound Be-9 beam was performed at LNS Catania. Elastic scattering angular distributions have been measured for the three systems Be-9,Be-10,Be-11 + Zn-64 at the same center of mass energy. The angular distributions were analyzed with optical potentials and reaction cross sections were obtained from optical model calculations, performed with the code PTOLEMY. For the Be-11 + Zn-64 reaction, the break-up angular distribution was also measured.

  18. The CMS Beam Halo Monitor Detector System

    CERN Document Server

    CMS Collaboration

    2015-01-01

    A new Beam Halo Monitor (BHM) detector system has been installed in the CMS cavern to measure the machine-induced background (MIB) from the LHC. This background originates from interactions of the LHC beam halo with the final set of collimators before the CMS experiment and from beam gas interactions. The BHM detector uses the directional nature of Cherenkov radiation and event timing to select particles coming from the direction of the beam and to suppress those originating from the interaction point. It consists of 40 quartz rods, placed on each side of the CMS detector, coupled to UV sensitive PMTs. For each bunch crossing the PMT signal is digitized by a charge integrating ASIC and the arrival time of the signal is recorded. The data are processed in real time to yield a precise measurement of per-bunch-crossing background rate. This measurement is made available to CMS and the LHC, to provide real-time feedback on the beam quality and to improve the efficiency of data taking. In this talk we will describ...

  19. The CMS Beam Halo Monitor Detector System

    CERN Document Server

    Stifter, Kelly

    2015-01-01

    A new Beam Halo Monitor (BHM) detector system has been installed in the CMS cavern to measure the machine-induced background (MIB) from the LHC. This background originates from interactions of the LHC beam halo with the final set of collimators before the CMS experiment and from beam gas interactions. The BHM detector uses the directional nature of Cherenkov radiation and event timing to select particles coming from the direction of the beam and to supress those originating from the interaction point. It consists of 40 quartz rods, placed on each side of the CMS detector, coupled to UV sensitive PMTs. For each bunch crossing the PMT signal is digitized by a charge integrating ASIC and the arrival time of the signal is recorded. The data are processed in real time to yield a precise measurement of per-bunch-crossing background rate. This measurement is made available to CMS and the LHC, to provide real-time feedback on the beam quality and to improve the efficiency of data taking. In this talk we will descri...

  20. Degradation of HaloTag-fused nuclear proteins using bestatin-HaloTag ligand hybrid molecules.

    Science.gov (United States)

    Tomoshige, Shusuke; Naito, Mikihiko; Hashimoto, Yuichi; Ishikawa, Minoru

    2015-10-14

    We have developed a protein knockdown technology using hybrid small molecules designed as conjugates of a ligand for the target protein and a ligand for ubiquitin ligase cellular inhibitor of apoptosis protein 1 (cIAP1). However, this technology has several limitations. Here, we report the development of a novel protein knockdown system to address these limitations. In this system, target proteins are fused with HaloTag to provide a common binding site for a degradation inducer. We designed and synthesized small molecules consisting of alkyl chloride as the HaloTag-binding degradation inducer, which binds to HaloTag, linked to BE04 (2), which binds to cIAP1. Using this system, we successfully knocked down HaloTag-fused cAMP responsive element binding protein 1 (HaloTag-CREB1) and HaloTag-fused c-jun (HaloTag-c-jun), which are ligand-unknown nuclear proteins, in living cells. HaloTag-binding degradation inducers can be synthesized easily, and are expected to be useful as biological tools for pan-degradation of HaloTag-fused proteins.

  1. Halo-induced large enhancement of soft dipole excitation of 11Li observed via proton inelastic scattering

    Directory of Open Access Journals (Sweden)

    J. Tanaka

    2017-11-01

    Full Text Available Proton inelastic scattering off a neutron halo nucleus, 11Li, has been studied in inverse kinematics at the IRIS facility at TRIUMF. The aim was to establish a soft dipole resonance and to obtain its dipole strength. Using a high quality 66 MeV 11Li beam, a strongly populated excited state in 11Li was observed at Ex=0.80±0.02 MeV with a width of Γ=1.15±0.06 MeV. A DWBA (distorted-wave Born approximation analysis of the measured differential cross section with isoscalar macroscopic form factors leads us to conclude that this observed state is excited in an electric dipole (E1 transition. Under the assumption of isoscalar E1 transitions, the strength is evaluated to be extremely large amounting to 30∼296 Weisskopf units, exhausting 2.2%∼21% of the isoscalar E1 energy-weighted sum rule (EWSR value. The large observed strength originates from the halo and is consistent with the simple di-neutron model of 11Li halo.

  2. Halo-induced large enhancement of soft dipole excitation of 11Li observed via proton inelastic scattering

    Science.gov (United States)

    Tanaka, J.; Kanungo, R.; Alcorta, M.; Aoi, N.; Bidaman, H.; Burbadge, C.; Christian, G.; Cruz, S.; Davids, B.; Diaz Varela, A.; Even, J.; Hackman, G.; Harakeh, M. N.; Henderson, J.; Ishimoto, S.; Kaur, S.; Keefe, M.; Krücken, R.; Leach, K. G.; Lighthall, J.; Padilla Rodal, E.; Randhawa, J. S.; Ruotsalainen, P.; Sanetullaev, A.; Smith, J. K.; Workman, O.; Tanihata, I.

    2017-11-01

    Proton inelastic scattering off a neutron halo nucleus, 11Li, has been studied in inverse kinematics at the IRIS facility at TRIUMF. The aim was to establish a soft dipole resonance and to obtain its dipole strength. Using a high quality 66 MeV 11Li beam, a strongly populated excited state in 11Li was observed at Ex = 0.80 ± 0.02 MeV with a width of Γ = 1.15 ± 0.06 MeV. A DWBA (distorted-wave Born approximation) analysis of the measured differential cross section with isoscalar macroscopic form factors leads us to conclude that this observed state is excited in an electric dipole (E1) transition. Under the assumption of isoscalar E1 transitions, the strength is evaluated to be extremely large amounting to 30 ∼ 296 Weisskopf units, exhausting 2.2% ∼ 21% of the isoscalar E1 energy-weighted sum rule (EWSR) value. The large observed strength originates from the halo and is consistent with the simple di-neutron model of 11Li halo.

  3. Characteristic time for halo current growth and rotation

    Energy Technology Data Exchange (ETDEWEB)

    Boozer, Allen H., E-mail: ahb17@columbia.edu [Department of Applied Physics and Applied Mathematics, Columbia University, New York, New York 10027 (United States)

    2015-10-15

    A halo current flows for part of its path through the plasma edge and for part through the chamber walls and during tokamak disruptions can be as large as tenths of the plasma current. The primary interest in halo currents is the large force that they can exert on machine components particularly if the toriodal rotation of the halo current resonates with a natural oscillation frequency of the tokamak device. Halo currents arise when required to slow down the growth of a kink that is too unstable to be stabilized by the chamber walls. The width of the current channel in the halo plasma is comparable to the amplitude of the kink, and the halo current grows linearly, not exponentially, in time. The current density in the halo is comparable to that of the main plasma body. The rocket force due to plasma flowing out of the halo and recombining on the chamber walls can cause the non-axisymmetric magnetic structure produced by the kink to rotate toroidally at a speed comparable to the halo speed of sound. Gerhardt's observations of the halo current in NSTX shot 141 687 [Nucl. Fusion 53, 023005 (2013)] illustrate many features of the theory of halo currents and are discussed as a summary of the theory.

  4. Analytical halo model of galactic conformity

    Science.gov (United States)

    Pahwa, Isha; Paranjape, Aseem

    2017-09-01

    We present a fully analytical halo model of colour-dependent clustering that incorporates the effects of galactic conformity in a halo occupation distribution framework. The model, based on our previous numerical work, describes conformity through a correlation between the colour of a galaxy and the concentration of its parent halo, leading to a correlation between central and satellite galaxy colours at fixed halo mass. The strength of the correlation is set by a tunable 'group quenching efficiency', and the model can separately describe group-level correlations between galaxy colour (1-halo conformity) and large-scale correlations induced by assembly bias (2-halo conformity). We validate our analytical results using clustering measurements in mock galaxy catalogues, finding that the model is accurate at the 10-20 per cent level for a wide range of luminosities and length-scales. We apply the formalism to interpret the colour-dependent clustering of galaxies in the Sloan Digital Sky Survey (SDSS). We find good overall agreement between the data and a model that has 1-halo conformity at a level consistent with previous results based on an SDSS group catalogue, although the clustering data require satellites to be redder than suggested by the group catalogue. Within our modelling uncertainties, however, we do not find strong evidence of 2-halo conformity driven by assembly bias in SDSS clustering.

  5. The new Beam Halo Monitor for the CMS experiment at the LHC

    CERN Document Server

    Tosi, Nicolo

    In the context of increasing beam energy and luminosity of the LHC accelerator at CERN, it will be important to accurately measure the Machine Induced Background. A new monitoring system will be installed in the CMS cavern for measuring the beam background at high radius. This detector, called the Beam Halo Monitor, will provide an online, bunch-by-bunch measurement of background induced by beam halo interactions, separately for each beam. The detector is composed of synthetic quartz Cherenkov radiators, coupled to fast UV sensitive photomultiplier tubes. The directional and fast response of the system allows the discrimination of the background particles from the dominant flux in the cavern induced by pp collision debris, produced within the 25 ns bunch spacing. The readout electronics of this detector will make use of many components developed for the upgrade of the CMS Hadron Calorimeter electronics, with a dedicated firmware and readout adapted to the beam monitoring requirements. The PMT signal will be d...

  6. Halo Mitigation Using Nonlinear Lattices

    CERN Document Server

    Sonnad, Kiran G

    2005-01-01

    This work shows that halos in beams with space charge effects can be controlled by combining nonlinear focusing and collimation. The study relies on Particle-in-Cell (PIC) simulations for a one dimensional, continuous focusing model. The PIC simulation results show that nonlinear focusing leads to damping of the beam oscillations thereby reducing the mismatch. It is well established that reduced mismatch leads to reduced halo formation. However, the nonlinear damping is accompanied by emittance growth causing the beam to spread in phase space. As a result, inducing nonlinear damping alone cannot help mitigate the halo. To compensate for this expansion in phase space, the beam is collimated in the simulation and further evolution of the beam shows that the halo is not regenerated. The focusing model used in the PIC is analysed using the Lie Transform perturbation theory showing that by averaging over a lattice period, one can reuduce the focusing force to a form that is identical to that used in the PIC simula...

  7. Isospin in halo nuclei: Borromean halo, tango halo, and halo isomers

    Science.gov (United States)

    Izosimov, I. N.

    2017-09-01

    It is shown that the wave functions for isobaric analog, double isobaric analog, configuration, and double configuration states may simultaneously have components corresponding to nn, np, and pp halos. The difference in the halo structure between the ground and excited states of a nucleus may lead to the formation of halo isomers. A halo structure of both Borromean and tango types can be observed for np configurations. The structure of ground and excited states with various isospins in halo-like nuclei is discussed. The reduced probabilities B( Mλ) and B( Eλ) for gamma transitions in 6-8Li, 8-10Be, 8,10,11B, 10-14C, 13-17N, 15-17,19O, and 17F nuclei are analyzed. Particular attention is given to the cases where the ground state of a nucleus does not have a halo structure, but where its excited state may have it.

  8. Coupled-channels effects in elastic scattering and near-barrier fusion induced by weakly bound nuclei and exotic halo nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Beck, C. [Institut Pluridisciplinaire Hubert Curien, UMR 7178, IN2P3-CNRS et Universite Louis Pasteur (Strasbourg I), 23 rue du Loess - BP28, F-67037 Strasbourg Cedex 2 (France); Keeley, N. [DSM/DAPNIA/SPhN CEA Saclay, Orme des Merisiers, F-91191 Gif-sur-Yvette Cedex (France); Diaz-Torres, A. [Department of Nuclear Physics, Research School of Physical Sciences and Engineering, The Australian National University, Canberra ACT 0200 (Australia)

    2007-03-15

    The influence on fusion of coupling to the breakup process is investigated for reactions where at least one of the colliding nuclei has a sufficiently low binding energy for breakup to become an important process. Elastic scattering, excitation functions for sub-and near-barrier fusion cross sections, and breakup yields are analyzed for {sup 6,7}Li+{sup 59}Co. Continuum-Discretized Coupled-Channels (CDCC) calculations describe well the data at and above the barrier. Elastic scattering with {sup 6}Li (as compared to {sup 7}Li) indicates the significant role of breakup for weakly bound projectiles. A study of {sup 4,6}He induced fusion reactions with a three-body CDCC method for the {sup 6}He halo nucleus is presented. The relative importance of breakup and bound-state structure effects on total fusion is discussed. (authors)

  9. The evolution of machining-induced surface of single-crystal FCC copper via nanoindentation.

    Science.gov (United States)

    Zhang, Lin; Huang, Hu; Zhao, Hongwei; Ma, Zhichao; Yang, Yihan; Hu, Xiaoli

    2013-05-04

    The physical properties of the machining-induced new surface depend on the performance of the initial defect surface and deformed layer in the subsurface of the bulk material. In this paper, three-dimensional molecular dynamics simulations of nanoindentation are preformed on the single-point diamond turning surface of single-crystal copper comparing with that of pristine single-crystal face-centered cubic copper. The simulation results indicate that the nucleation of dislocations in the nanoindentation test on the machining-induced surface and pristine single-crystal copper is different. The dislocation embryos are gradually developed from the sites of homogeneous random nucleation around the indenter in the pristine single-crystal specimen, while the dislocation embryos derived from the vacancy-related defects are distributed in the damage layer of the subsurface beneath the machining-induced surface. The results show that the hardness of the machining-induced surface is softer than that of pristine single-crystal copper. Then, the nanocutting simulations are performed along different crystal orientations on the same crystal surface. It is shown that the crystal orientation directly influences the dislocation formation and distribution of the machining-induced surface. The crystal orientation of nanocutting is further verified to affect both residual defect generations and their propagation directions which are important in assessing the change of mechanical properties, such as hardness and Young's modulus, after nanocutting process.

  10. ALFA beam halo

    CERN Document Server

    Komarek, Tomas

    2014-01-01

    This note serves as a final report about CERN Summer Student Programme 2014 project. The beam halo is an undesired phenomenon for physics analyses on particle accelerators. It surrounds the beam core and constitutes an important part of background for signal measurements on some detectors, eg. in the forward region. In this study, the data from the ALFA detector were used, specifically from the run 191373 ($\\beta^*=90\\unit{m}$) and the run 213268 ($\\beta^*=1\\unit{km}$). Using the ROOT framework, a software for beam halo events selection was created and beam halo properties were examined. In the run 213268, excessive beam halo is suspected to be the reason for multiple beam scrapings that occurred. A kinematic reconstruction of beam halo particles is attempted in order to understand beam halo properties in the interaction point. Some further simulations are employed to find constraints for beam halo particles in order to survive in the accelerator for a longer time/many revolutions. This work represents a st...

  11. The CMS Beam Halo Monitor electronics

    Science.gov (United States)

    Tosi, N.; Dabrowski, A. E.; Fabbri, F.; Grassi, T.; Hughes, E.; Mans, J.; Montanari, A.; Orfanelli, S.; Rusack, R.; Torromeo, G.; Stickland, D. P.; Stifter, K.

    2016-02-01

    The CMS Beam Halo Monitor has been successfully installed in the CMS cavern in LHC Long Shutdown 1 for measuring the machine induced background for LHC Run II. The system is based on 40 detector units composed of synthetic quartz Cherenkov radiators coupled to fast photomultiplier tubes (PMTs). The readout electronics chain uses many components developed for the Phase 1 upgrade to the CMS Hadronic Calorimeter electronics, with dedicated firmware and readout adapted to the beam monitoring requirements. The PMT signal is digitized by a charge integrating ASIC (QIE10), providing both the signal rise time, with few nanosecond resolution, and the charge integrated over one bunch crossing. The backend electronics uses microTCA technology and receives data via a high-speed 5 Gbps asynchronous link. It records histograms with sub-bunch crossing timing resolution and is read out via IPbus using the newly designed CMS data acquisition for non-event based data. The data is processed in real time and published to CMS and the LHC, providing online feedback on the beam quality. A dedicated calibration monitoring system has been designed to generate short triggered pulses of light to monitor the efficiency of the system. The electronics has been in operation since the first LHC beams of Run II and has served as the first demonstration of the new QIE10, Microsemi Igloo2 FPGA and high-speed 5 Gbps link with LHC data.

  12. Performance of the CMS Beam Halo Monitor

    CERN Document Server

    CMS Collaboration

    2015-01-01

    The CMS Beam Halo Monitor has been successfully installed in the CMS cavern in LHC Long Shutdown 1 for measuring the machine induced background for LHC Run II. The system is based on 40 detector units composed of radiation hard synthetic quartz Cherenkov radiators coupled to fast photomultiplier tubes for a direction sensitive measurement. The readout electronics chain uses many components developed for the Phase 1 upgrade to the CMS Hadronic Calorimeter electronics, with dedicated firmware and readout adapted to the beam monitoring requirements. The PMT signal is digitized by a charge integrating ASIC (QIE10), providing both the signal rise time, with few ns resolution, and the charge integrated over one bunch crossing. The backend electronics uses microTCA technology and received data via a high-speed 5 Gbps asynchronous link. It records histograms with sub-bunch crossing timing resolution and is readout by IPbus using the newly designed CMS data acquisition for non-event based data. The data is processed i...

  13. The CMS Beam Halo Monitor Electronics

    CERN Document Server

    AUTHOR|(CDS)2080684; Fabbri, F.; Grassi, T.; Hughes, E.; Mans, J.; Montanari, A.; Orfanelli, S.; Rusack, R.; Torromeo, G.; Stickland, D.P.; Stifter, K.

    2016-01-01

    The CMS Beam Halo Monitor has been successfully installed in the CMS cavern in LHC Long Shutdown 1 for measuring the machine induced background for LHC Run II. The system is based on 40 detector units composed of synthetic quartz Cherenkov radiators coupled to fast photomultiplier tubes. The readout electronics chain uses many components developed for the Phase 1 upgrade to the CMS Hadronic Calorimeter electronics, with dedicated firmware and readout adapted to the beam monitoring requirements. The PMT signal is digitized by a charge integrating ASIC (QIE10), providing both the signal rise time, with few ns resolution, and the charge integrated over one bunch crossing. The backend electronics uses microTCA technology and receives data via a high-speed 5 Gbps asynchronous link. It records histograms with sub-bunch crossing timing resolution and is readout by IPbus using the newly designed CMS data acquisition for non-event based data. The data is processed in real time and published to CMS and the LHC, providi...

  14. What's a Halo?

    Science.gov (United States)

    ... Development Infections Diseases & Conditions Pregnancy & Baby Nutrition & Fitness Emotions & Behavior School & Family Life First Aid & Safety Doctors & ... of quick or jerky movements, like jumping or dancing pulling or tugging on the halo or attached ...

  15. Testing baryon-induced core formation in ΛCDM: A comparison of the DC14 and coreNFW dark matter halo models on galaxy rotation curves

    Science.gov (United States)

    Allaert, F.; Gentile, G.; Baes, M.

    2017-09-01

    Recent cosmological hydrodynamical simulations suggest that baryonic processes, and in particular supernova feedback following bursts of star formation, can alter the structure of dark matter haloes and transform primordial cusps into shallower cores. To assess whether this mechanism offers a solution to the long-standing cusp-core controversy, simulated haloes must be compared to real dark matter haloes inferred from galaxy rotation curves. For this purpose, two new dark matter density profiles were recently derived from simulations of galaxies in complementary mass ranges: the DC14 halo (1010 study, but strongly refuted by another. A next important question is whether, despite their different approaches, the two models converge to the same solution in the mass range where both should be appropriate. To investigate this, we tested the DC14 and coreNFW halo models on the rotation curves of a selection of galaxies with halo masses in the range 4 × 109M⊙ - 7 × 1010M⊙ and compared their predictions. We further applied the DC14 model to a set of rotation curves at higher halo masses, up to 9 × 1011M⊙, to verify the agreement with the cosmological scaling relations. Both models are generally able to reproduce the observed rotation curves, in line with earlier results, and the predicted dark matter haloes are consistent with the cosmological c-Mhalo and M∗-Mhalo relations. We find that the DC14 and coreNFW models are also in fairly good agreement with each other, even though DC14 tends to predict slightly less extended cores and somewhat more concentrated haloes than coreNFW. While the quality of the fits is generally similar for both halo models, DC14 does perform significantly better than coreNFW for three galaxies. In each of these cases, the problem for coreNFW is related to connection of the core size to the stellar half-mass radius, although we argue that it is justifiable to relax this connection for NGC 3741. A larger core radius brings the core

  16. Halo formation from mismatched beam-beam interactions

    Energy Technology Data Exchange (ETDEWEB)

    Qiang, Ji

    2003-05-23

    In this paper, we report on the halo formation and emittance growth driven by a parametric resonance during mismatched beam-beam collisions. In the regime of the weak-strong beam-beam interaction, if two beams have the same machine tunes, on-axis head-on collisions between a mismatched strong beam and a weak beam will not cause the formation of halo. However, if the two beams collide with an initial offset, the beam-beam force from the mismatched strong beam can cause halo formation and emittance growth in the weak beam. Meanwhile, if two beams have different machine tunes, for opposite charged colliding beams, when the machine tune of the weak beam is smaller than that of strong beam, there is emittance growth in the weak beam. When the machine tune of the weak beam is larger than that of the strong beam, there is little emittance growth. In the regime of strong-strong beam-beam interaction, halo is formed in both beams even when the two beams collide head-on on the axis with equal machine tunes. This puts a strong requirement for a good beam match during the injection to colliders in order to avoid the emittance growth.

  17. Spectrum of Sprite Halos

    Czech Academy of Sciences Publication Activity Database

    Gordillo-Vázquez, F.J.; Luque, A.; Šimek, Milan

    2011-01-01

    Roč. 116, č. 9 (2011), A09319-A09319 ISSN 0148-0227 Institutional research plan: CEZ:AV0Z20430508 Keywords : sprites * halos * spectroscopy Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 3.021, year: 2011 http://www.trappa.iaa.es/sites/all/files/papers/isi_journal_papers/2011/2011_08.pdf

  18. Machine learning-based prediction of adverse drug effects: An example of seizure-inducing compounds.

    Science.gov (United States)

    Gao, Mengxuan; Igata, Hideyoshi; Takeuchi, Aoi; Sato, Kaoru; Ikegaya, Yuji

    2017-02-01

    Various biological factors have been implicated in convulsive seizures, involving side effects of drugs. For the preclinical safety assessment of drug development, it is difficult to predict seizure-inducing side effects. Here, we introduced a machine learning-based in vitro system designed to detect seizure-inducing side effects. We recorded local field potentials from the CA1 alveus in acute mouse neocortico-hippocampal slices, while 14 drugs were bath-perfused at 5 different concentrations each. For each experimental condition, we collected seizure-like neuronal activity and merged their waveforms as one graphic image, which was further converted into a feature vector using Caffe, an open framework for deep learning. In the space of the first two principal components, the support vector machine completely separated the vectors (i.e., doses of individual drugs) that induced seizure-like events and identified diphenhydramine, enoxacin, strychnine and theophylline as "seizure-inducing" drugs, which indeed were reported to induce seizures in clinical situations. Thus, this artificial intelligence-based classification may provide a new platform to detect the seizure-inducing side effects of preclinical drugs. Copyright © 2017 The Authors. Production and hosting by Elsevier B.V. All rights reserved.

  19. Machine-induced showers entering the ATLAS and CMS detectors in the LHC

    CERN Document Server

    Bruce, R; Boccone, V; Burkhardt, H; Cerutti, F; Ferrari, A; Huhtinen, M; Kozanecki, W; Levinsen, Y; Mereghetti, A; Rossi, A; Mokhov, N V; Weiler, T

    2011-01-01

    One source of experimental background in the LHC is showers induced by particles hitting the upstream collimators or particles that have been scattered on the residual gas. We estimate the flux and distribution of particles entering the ATLAS and CMS detectors through FLUKA simulations starting either in the tertiary collimators or with inelastic beam-gas interactions. Comparisons to MARS15 results are also presented. Our results can be used as a source term for further simulations of the machine-induced background in the experimental detectors.

  20. Laser Induced Breakdown Spectroscopy machine for online ash analyses in coal

    Energy Technology Data Exchange (ETDEWEB)

    Gaft, M. [Research Department, LDS, 11 Granit St., Petach Tikva 49002 (Israel)], E-mail: michaelg@laserdetect.com; Dvir, E.; Modiano, H.; Schone, U. [Research Department, LDS, 11 Granit St., Petach Tikva 49002 (Israel)

    2008-10-15

    Presently, online coal ash content monitoring is performed by PGNAA (Prompt Gamma Neutron Activation Analyses) machines. Laser Detect Systems has developed an online mineral analysis system using Laser Induced Breakdown Spectroscopy (LIBS). The main advantages of the system are that it is without a radioactive source, compact (1.5 m x 0.8 m x 1.3 m), comparatively light (250 kg) and easy to install. The main disadvantage is that a LIBS system analyzes surface chemistry of the mineral exclusively and not the volume. To prove the LIBS machine analytical ability for coal ash content evaluation, a trial was arranged at Optimum Colliery (South Africa). The LIBS machine was installed in line with a PGNAA machine and laboratory data served as a referee in the final assessment for analytical accuracy. The trial was carried out over a four month period. This paper presents the successful trial results achieved for accurate (at least +/- 0.5% mean absolute error) online coal ash content monitoring.

  1. Machine learning-based prediction of adverse drug effects: An example of seizure-inducing compounds

    Directory of Open Access Journals (Sweden)

    Mengxuan Gao

    2017-02-01

    Full Text Available Various biological factors have been implicated in convulsive seizures, involving side effects of drugs. For the preclinical safety assessment of drug development, it is difficult to predict seizure-inducing side effects. Here, we introduced a machine learning-based in vitro system designed to detect seizure-inducing side effects. We recorded local field potentials from the CA1 alveus in acute mouse neocortico-hippocampal slices, while 14 drugs were bath-perfused at 5 different concentrations each. For each experimental condition, we collected seizure-like neuronal activity and merged their waveforms as one graphic image, which was further converted into a feature vector using Caffe, an open framework for deep learning. In the space of the first two principal components, the support vector machine completely separated the vectors (i.e., doses of individual drugs that induced seizure-like events and identified diphenhydramine, enoxacin, strychnine and theophylline as “seizure-inducing” drugs, which indeed were reported to induce seizures in clinical situations. Thus, this artificial intelligence-based classification may provide a new platform to detect the seizure-inducing side effects of preclinical drugs.

  2. Study and implementation high speed operating of induced magnetization machines; Etude et mise en oeuvre de machines a aimantation induite fonctionnant a haute vitesse

    Energy Technology Data Exchange (ETDEWEB)

    Alhassoun, Y.

    2005-05-15

    Actually, electromechanical machines are characterized by their low cost and reduced maintenance. Therefore, new types of magnetic materials such as soft magnetic composites (SMC), have to be considered not only for multiple applications (small motors for automotive) for cost reduction, but also when considering other special requirements such as high speed drive (aircraft and space applications). Our report of thesis is articulated around four chapters: The first chapter show the various types of magnetic interactions used in the electromagnetic actuators. The second chapter is devoted to the modelling of the induced magnetic machines by analytical resolution of equations of the field in two dimensions. The third chapter presents the four configurations prototypes of switched reluctance machine which mix the exploitation of laminated materials and the soft magnetic powders. The fourth chapter discusses the critical conditions of this machines operating at high speed. We conclude, insisting on the efforts carried out in term of analytical modelling of the induced magnetization machines for their dimensions and exploited in this same structure, the soft magnetic composite materials. The results show the potential of soft magnetic powders when considering in particular the high frequency losses and their ability to favour the heat dissipation in this structure. (author)

  3. [Halos and multifocal intraocular lenses: origin and interpretation].

    Science.gov (United States)

    Alba-Bueno, F; Vega, F; Millán, M S

    2014-10-01

    To present the theoretical and experimental characterization of the halo in multifocal intraocular lenses (MIOL). The origin of the halo in a MIOL is the overlaying of 2 or more images. Using geometrical optics, it can be demonstrated that the diameter of each halo depends on the addition of the lens (ΔP), the base power (P(d)), and the diameter of the IOL that contributes to the «non-focused» focus. In the image plane that corresponds to the distance focus, the halo diameter (δH(d)) is given by: δH(d)=d(pn) ΔP/P(d), where d(pn) is the diameter of the IOL that contributes to the near focus. Analogously, in the near image plane the halo diameter (δH(n)) is: δH(n)=d(pd) ΔP/P(d), where d(pd) is the diameter of the IOL that contributes to the distance focus. Patients perceive halos when they see bright objects over a relatively dark background. In vitro, the halo can be characterized by analyzing the intensity profile of the image of a pinhole that is focused by each of the foci of a MIOL. A comparison has been made between the halos induced by different MIOL of the same base power (20D) in an optical bench. As predicted by theory, the larger the addition of the MIOL, the larger the halo diameter. For large pupils and with MIOL with similar aspheric designs and addition (SN6AD3 vs ZMA00), the apodized MIOL has a smaller halo diameter than a non-apodized one in distance vision, while in near vision the size is very similar, but the relative intensity is higher in the apodized MIOL. When comparing lenses with the same diffractive design, but with different spherical-aspheric base design (SN60D3 vs SN6AD3), the halo in distance vision of the spherical MIOL is larger, while in near vision the spherical IOL induces a smaller halo, but with higher intensity due to the spherical aberration of the distance focus in the near image. In the case of a trifocal-diffractive IOL (AT LISA 839MP) the most noticeable characteristic is the double-halo formation due to the 2 non

  4. Signatures of compact halos of sterile-neutrino dark matter

    Science.gov (United States)

    Kühnel, Florian; Ohlsson, Tommy

    2017-11-01

    We investigate compact halos of sterile-neutrino dark matter and examine observable signatures with respect to neutrino and photon emission. Primarily, we consider two cases: primordial black-hole halos and ultracompact minihalos. In both cases, we find that there exists a broad range of possible parameter choices such that detection in the near future with x-ray and gamma-ray telescopes might be well possible. In fact, for energies above 10 TeV, the neutrino telescope IceCube would be a splendid detection machine for such macroscopic dark-matter candidates.

  5. Effect of Thermal Annealing on Machining-Induced Residual Stresses in Inconel 718

    Science.gov (United States)

    Madariaga, A.; Aperribay, J.; Arrazola, P. J.; Esnaola, J. A.; Hormaetxe, E.; Garay, A.; Ostolaza, K.

    2017-08-01

    Nickel-based alloys are widely employed in the manufacturing of aero-engines. These alloys are difficult to machine, and tensile residual stresses are generated during machining. These tensile residual stresses can negatively affect the performance of aero-engine components. Nevertheless, residual stresses can vary due to thermal or mechanical loading. These variations must be considered to evaluate the real influence of residual stresses on component behavior. This paper studies the effect of thermal loads on machining-induced residual stresses in the alloy Inconel 718. A ring-shaped Inconel 718 part was face-turned, and specimens were extracted from it. Specimens were exposed at 550 and 650 °C for 10 min, 1 and 10 h. Residual stresses were measured, and microstructure was observed before and after thermal exposure. Residual stress variations found after thermal exposure were the consequence of two factors: relaxation of strain bands during the early stage of exposure and diffusion-controlled creep. In addition, a modified Zener-Wert-Avrami model is proposed to predict residual stress relaxation caused by the diffusion-controlled creep. Once having fitted the modified Zener-Wert-Avrami model, the study was extended for a wider range of temperatures (400-650 °C). This analysis showed that surface residual stresses do not relax significantly at temperatures below 500 °C.

  6. MD 1691: Active halo control using tune ripple at injection

    CERN Document Server

    Garcia Morales, Hector; Bruce, Roderik; Redaelli, Stefano; Fitterer, Miriam; Fiascaris, Maria; Nisbet, David; Thiesen, Hugues; Valentino, Gianluca; Xu, Chen; CERN. Geneva. ATS Department

    2017-01-01

    In this MD we performed halo excitation through tune ripple. This consists in an excitation that introduces new resonance sidebands around the existing resonance lines. In presence of sufficient detuning with amplitude, these sidebands can in principle affect only the dynamics of the halo particles at large amplitudes. Tune ripple was induced through a current modulation of the warm trim quadrupoles in IR7. This is the first time this method is experimentally tested at the LHC.

  7. Upgrade of the CMS Instrumentation for luminosity and machine induced background measurements

    Science.gov (United States)

    Dabrowski, Anne; CMS Collaboration

    2016-04-01

    To optimise performance with the higher luminosity, higher beam energy and shorter bunch spacing of 25 ns at the LHC after 2014, an upgrade program is performed for the detectors to measure the luminosity and machine induced background. A new detector is the pixel luminosity telescope consisting of 8 telescopes, equipped with silicon pixel sensors, on both ends of the interactions point. The Fast Beam Conditions Monitoring system, using diamond sensors, is upgraded to 24 sensors, 12 on each end of the IP. In addition, dedicated fast ASICs produced in 130 nm commercial CMOS technology and dead-time free backend electronics using FPGAs for fast signal processing are being developed and built. Also, the part of the forward HCAL used for the luminosity measurement is instrumented with new readout electronics, in microTCA standards. The machine induced background measurement will be supported by a new system of direction sensitive quartz Cherenkov counters, with excellent time resolution. A data acquisition architecture is being developed that is common for all subsystems and allows for synchronization across different hardware. The design of the new system will be presented, and a report will be given on the performance of each subsystem measured in several test-beam campaigns and prototype operation in the last LHC run.

  8. Impact of Neutrinos on Dark Matter Halo Environment

    Science.gov (United States)

    Court, Travis; Villaescusa-Navarro, Francisco

    2018-01-01

    The spatial clustering of galaxies is commonly used to infer the shape of the matter power spectrum and therefore to place constraints on the value of the cosmological parameters. In order to extract the maximum information from galaxy surveys it is required to provide accurate theoretical predictions. The first step to model galaxy clustering is to understand the spatial distribution of the structures where they reside: dark matter halos. I will show that the clustering of halos does not depend only on mass, but on other quantities like local matter overdensity. I will point out that halo clustering is also sensitive to the local overdensity of the cosmic neutrino background. I will show that splitting halos according to neutrino overdensity induces a very large scale-dependence bias, an effect that may lead to a new technique to constraint the sum of the neutrino masses.

  9. Cosmic web type dependence of halo clustering

    Science.gov (United States)

    Fisher, J. D.; Faltenbacher, A.

    2018-01-01

    We use the Millennium Simulation to show that halo clustering varies significantly with cosmic web type. Haloes are classified as node, filament, sheet and void haloes based on the eigenvalue decomposition of the velocity shear tensor. The velocity field is sampled by the peculiar velocities of a fixed number of neighbouring haloes, and spatial derivatives are computed using a kernel borrowed from smoothed particle hydrodynamics. The classification scheme is used to examine the clustering of haloes as a function of web type for haloes with masses larger than 1011 h- 1 M⊙. We find that node haloes show positive bias, filament haloes show negligible bias and void and sheet haloes are antibiased independent of halo mass. Our findings suggest that the mass dependence of halo clustering is rooted in the composition of web types as a function of halo mass. The substantial fraction of node-type haloes for halo masses ≳ 2 × 1013 h- 1 M⊙ leads to positive bias. Filament-type haloes prevail at intermediate masses, 1012-1013 h- 1 M⊙, resulting in unbiased clustering. The large contribution of sheet-type haloes at low halo masses ≲ 1012 h- 1 M⊙ generates antibiasing.

  10. An experimental study on the effect of parameters on the depth of crater machined by electrostatic field–induced electrolyte jet micro electrical discharge machining

    Directory of Open Access Journals (Sweden)

    Yaou Zhang

    2016-04-01

    Full Text Available Electrostatic field–induced electrolyte jet micro electrical discharge machining depends on heat generated by the periodic pulsed discharge between the workpiece and the electrolyte fine jet from the tip of Taylor cone, induced by the intense electric field, to erode the material from the workpiece. To further investigate the characteristics of this discharge process, with the NaCl solution as the electrostatic field–induced electrolyte jet electrolyte and the silicon wafer as the workpiece, the governing factors of machining polarity, nozzle-to-workpiece distance, voltage applied between positive and negative polarities, and the effect of concentration of the electrolyte on the depth of crater after a single electrostatic field–induced electrolyte jet discharge have been studied. The experimental results show that the average depth of crater increases with the increase in the voltage applied between the nozzle and the workpiece, and increases with the increase in the concentration of the electrolyte, but decreases with the increase in the distance between the nozzle and the workpiece. The results have also demonstrated that the polarity has no clear influence on the average depth of crater after a single discharge.

  11. Black holes with halos

    Science.gov (United States)

    Monten, Ruben; Toldo, Chiara

    2018-02-01

    We present new AdS4 black hole solutions in N =2 gauged supergravity coupled to vector and hypermultiplets. We focus on a particular consistent truncation of M-theory on the homogeneous Sasaki–Einstein seven-manifold M 111, characterized by the presence of one Betti vector multiplet. We numerically construct static and spherically symmetric black holes with electric and magnetic charges, corresponding to M2 and M5 branes wrapping non-contractible cycles of the internal manifold. The novel feature characterizing these nonzero temperature configurations is the presence of a massive vector field halo. Moreover, we verify the first law of black hole mechanics and we study the thermodynamics in the canonical ensemble. We analyze the behavior of the massive vector field condensate across the small-large black hole phase transition and we interpret the process in the dual field theory.

  12. Diagnosis and control of machine induced noise and vibration in steel construction

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Wei Yu; Wang, Wei Hui [National Taiwan Ocean University, Keelung (China)

    2008-11-15

    Most high-rise buildings constructed of steel or steel reinforced concrete have to install various vital equipment. Among these equipment machinery noise is especially annoying for accommodation close to them. In attempting to control the machine-induced structure-borne noise and vibration, the methodology by employing mobility functions to identify the dominant frequency band of vibrational power flow transmission and to assess the isolation effectiveness of isolators is established. The proposed method of diagnosis procedure is applied to the structure-borne vibration power flow transmission for a steel construction parking tower. After proper check and replacement of the isolators of the power unit platform of the mechanical parking tower, the improvement results in a substantial structure-borne noise reduction of 16 dB(NC). The unique parts of the paper include the establishment of the relation of mobility functions with respect to four-pole parameters for a coupled machine/mount/foundation system. Also expressions to represent the vibrational input power, the output power and the transmitted power in relation to mobility functions are clarified

  13. Machine Learning Approach to Automated Quality Identification of Human Induced Pluripotent Stem Cell Colony Images.

    Science.gov (United States)

    Joutsijoki, Henry; Haponen, Markus; Rasku, Jyrki; Aalto-Setälä, Katriina; Juhola, Martti

    2016-01-01

    The focus of this research is on automated identification of the quality of human induced pluripotent stem cell (iPSC) colony images. iPS cell technology is a contemporary method by which the patient's cells are reprogrammed back to stem cells and are differentiated to any cell type wanted. iPS cell technology will be used in future to patient specific drug screening, disease modeling, and tissue repairing, for instance. However, there are technical challenges before iPS cell technology can be used in practice and one of them is quality control of growing iPSC colonies which is currently done manually but is unfeasible solution in large-scale cultures. The monitoring problem returns to image analysis and classification problem. In this paper, we tackle this problem using machine learning methods such as multiclass Support Vector Machines and several baseline methods together with Scaled Invariant Feature Transformation based features. We perform over 80 test arrangements and do a thorough parameter value search. The best accuracy (62.4%) for classification was obtained by using a k-NN classifier showing improved accuracy compared to earlier studies.

  14. Machine Learning Approach to Automated Quality Identification of Human Induced Pluripotent Stem Cell Colony Images

    Directory of Open Access Journals (Sweden)

    Henry Joutsijoki

    2016-01-01

    Full Text Available The focus of this research is on automated identification of the quality of human induced pluripotent stem cell (iPSC colony images. iPS cell technology is a contemporary method by which the patient’s cells are reprogrammed back to stem cells and are differentiated to any cell type wanted. iPS cell technology will be used in future to patient specific drug screening, disease modeling, and tissue repairing, for instance. However, there are technical challenges before iPS cell technology can be used in practice and one of them is quality control of growing iPSC colonies which is currently done manually but is unfeasible solution in large-scale cultures. The monitoring problem returns to image analysis and classification problem. In this paper, we tackle this problem using machine learning methods such as multiclass Support Vector Machines and several baseline methods together with Scaled Invariant Feature Transformation based features. We perform over 80 test arrangements and do a thorough parameter value search. The best accuracy (62.4% for classification was obtained by using a k-NN classifier showing improved accuracy compared to earlier studies.

  15. Development of a novel diamond based detector for machine induced background and luminosity measurements

    Energy Technology Data Exchange (ETDEWEB)

    Hempel, Maria

    2017-07-15

    The Large Hadron Collider (LHC) is the largest particle accelerator and storage ring in the world, used to investigate fundamentals of particle physics and to develop at the same time the technology of accelerators and detectors. Four main experiments, located around the LHC ring, provide insight into the nature of particles and search for answers to as yet unexplained phenomena in the universe. These four experiments are ATLAS (A Toroidal LHC Apparatus), ALICE (A Large Ion Collider Experiment), CMS (Compact Muon Solenoid) and LHCb (LHC beauty). Two proton or heavy ion beams circulate in the LHC and are brought into collision in the four experiments. The physics potential of each experiment is determined by the luminosity, which is a ratio of the number of the events during a certain time period to the cross section of a physics process. A measurement of the luminosity is therefore essential to determine the cross section of interesting physics processes. In addition, safe and high-quality data-taking requires stable beam conditions with almost no beam losses. So-called beam loss monitors are installed in the LHC rings to monitor beam losses around the LHC. Each experiment has in addition its own detectors to measure beam losses, hereafter called machine induced background. One such detector is installed in CMS, the Fast Beam Condition Monitor (BCM1F). Based on diamond sensors it was designed and built to measure both, the luminosity and the machine induced background. BCM1F ran smoothly during the first LHC running period from 2009-2012 and delivered valuable beam loss and luminosity information to the control rooms of CMS and LHC. At the end of 2012 the LHC was shut down for an upgrade to improve the performance by increasing the proton energy from 4 TeV to 7 TeV and decreasing the proton bunch spacing from 50 ns to 25 ns. Due to the success of BCM1F an upgrade of its sensors and readout components was planned in order to fulfil the new requirements. The upgrade

  16. The Excursion Set Theory of Halo Mass Functions, Halo Clustering, and Halo Growth

    Science.gov (United States)

    Zentner, Andrew R.

    I review the excursion set theory with particular attention toward applications to cold dark matter halo formation and growth, halo abundance, and halo clustering. After a brief introduction to notation and conventions, I begin by recounting the heuristic argument leading to the mass function of bound objects given by Press and Schechter. I then review the more formal derivation of the Press-Schechter halo mass function that makes use of excursion sets of the density field. The excursion set formalism is powerful and can be applied to numerous other problems. I review the excursion set formalism for describing both halo clustering and bias and the properties of void regions. As one of the most enduring legacies of the excursion set approach and one of its most common applications, I spend considerable time reviewing the excursion set theory of halo growth. This section of the review culminates with the description of two Monte Carlo methods for generating ensembles of halo mass accretion histories. In the last section, I emphasize that the standard excursion set approach is the result of several simplifying assumptions. Dropping these assumptions can lead to more faithful predictions and open excursion set theory to new applications. One such assumption is that the height of the barriers that define collapsed objects is a constant function of scale. I illustrate the implementation of the excursion set approach for barriers of arbitrary shape. One such application is the now well-known improvement of the excursion set mass function derived from the "moving" barrier for ellipsoidal collapse. I also emphasize that the statement that halo accretion histories are independent of halo environment in the excursion set approach is not a general prediction of the theory. It is a simplifying assumption. I review the method for constructing correlated random walks of the density field in the more general case. I construct a simple toy model to illustrate that excursion set

  17. Efficient protein knockdown of HaloTag-fused proteins using hybrid molecules consisting of IAP antagonist and HaloTag ligand.

    Science.gov (United States)

    Tomoshige, Shusuke; Hashimoto, Yuichi; Ishikawa, Minoru

    2016-07-15

    We previously reported a protein knockdown system for HaloTag-fused proteins using hybrid small molecules consisting of alkyl chloride, which binds covalently to HaloTag, linked to BE04 (2), a bestatin (3) derivative with an affinity for cellular inhibitor of apoptosis protein 1 (cIAP1, a kind of ubiquitin ligase). This system addressed several limitations of prior protein knockdown technology, and was applied to degrade two HaloTag-fused proteins. However, the degradation activity of these hybrid small molecules was not potent. Therefore, we set out to improve this system. We report here the design, synthesis and biological evaluation of novel hybrid compounds 4a and 4b consisting of alkyl chloride linked to IAP antagonist MV1 (5). Compounds 4a and 4b were confirmed to reduce the levels of HaloTag-fused tumor necrosis factor α (HaloTag-TNFα), HaloTag-fused cell division control protein 42 (HaloTag-Cdc42), and unfused HaloTag protein in living cells more potently than did BE04-linked compound 1b. Analysis of the mode of action revealed that the reduction of HaloTag-TNFα is proteasome-dependent, and is also dependent on the linker structure between MV1 (5) and alkyl chloride. These compounds appear to induce ubiquitination at the HaloTag moiety of HaloTag-fused proteins. Our results indicate that these newly synthesized MV1-type hybrid compounds, 4a and 4b, are efficient tools for protein knockdown for HaloTag-fused proteins. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. The abundance and environment of dark matter haloes

    Science.gov (United States)

    Metuki, Ofer; Libeskind, Noam I.; Hoffman, Yehuda

    2016-07-01

    An open question in cosmology and the theory of structure formation is to what extent does environment affect the properties of galaxies and haloes. The present paper aims at shedding light on this problem. The paper focuses on the analysis of a dark matter only simulation and it addresses the issue of how the environment affects the abundance of haloes, which are assigned four attributes: their virial mass, an ambient density calculated with an aperture that scales with Rvir (ΔM), a fixed-aperture (ΔR) ambient density, and a cosmic web classification (i.e. voids, sheets, filaments, and knots, as defined by the V-web algorithm). ΔM is the mean density around a halo evaluated within a sphere of a radius of 5Rvir, where Rvir is the virial radius. ΔR is the density field Gaussian smoothed with R = 4 h-1 Mpc, evaluated at the centre of the halo. The main result of the paper is that the difference between haloes in different web elements stems from the difference in their mass functions, and does not depend on their adaptive-aperture ambient density. A dependence on the fixed-aperture ambient density is induced by the cross-correlation between the mass of a halo and its fixed-aperture ambient density.

  19. Neutron halos in hypernuclei

    CERN Document Server

    Lue, H F; Meng, J; Zhou, S G

    2003-01-01

    Properties of single-LAMBDA and double-LAMBDA hypernuclei for even-N Ca isotopes ranging from the proton dripline to the neutron dripline are studied using the relativistic continuum Hartree-Bogolyubov theory with a zero-range pairing interaction. Compared with ordinary nuclei, the addition of one or two LAMBDA-hyperons lowers the Fermi level. The predicted neutron dripline nuclei are, respectively, sup 7 sup 5 subLAMBDA Ca and sup 7 sup 6 sub 2 subLAMBDA Ca, as the additional attractive force provided by the LAMBDA-N interaction shifts nuclei from outside to inside the dripline. Therefore, the last bound hypernuclei have two more neutrons than the corresponding ordinary nuclei. Based on the analysis of two-neutron separation energies, neutron single-particle energy levels, the contribution of continuum and nucleon density distribution, giant halo phenomena due to the pairing correlation, and the contribution from the continuum are suggested to exist in Ca hypernuclei similar to those that appear in ordinary ...

  20. Combining machine learning, crowdsourcing and expert knowledge to detect chemical-induced diseases in text.

    Science.gov (United States)

    Bravo, Àlex; Li, Tong Shu; Su, Andrew I; Good, Benjamin M; Furlong, Laura I

    2016-01-01

    Drug toxicity is a major concern for both regulatory agencies and the pharmaceutical industry. In this context, text-mining methods for the identification of drug side effects from free text are key for the development of up-to-date knowledge sources on drug adverse reactions. We present a new system for identification of drug side effects from the literature that combines three approaches: machine learning, rule- and knowledge-based approaches. This system has been developed to address the Task 3.B of Biocreative V challenge (BC5) dealing with Chemical-induced Disease (CID) relations. The first two approaches focus on identifying relations at the sentence-level, while the knowledge-based approach is applied both at sentence and abstract levels. The machine learning method is based on the BeFree system using two corpora as training data: the annotated data provided by the CID task organizers and a new CID corpus developed by crowdsourcing. Different combinations of results from the three strategies were selected for each run of the challenge. In the final evaluation setting, the system achieved the highest Recall of the challenge (63%). By performing an error analysis, we identified the main causes of misclassifications and areas for improving of our system, and highlighted the need of consistent gold standard data sets for advancing the state of the art in text mining of drug side effects.Database URL: https://zenodo.org/record/29887?ln¼en#.VsL3yDLWR_V. © The Author(s) 2016. Published by Oxford University Press.

  1. Halo modelling in chameleon theories

    Energy Technology Data Exchange (ETDEWEB)

    Lombriser, Lucas; Koyama, Kazuya [Institute of Cosmology and Gravitation, University of Portsmouth, Dennis Sciama Building, Burnaby Road, Portsmouth, PO1 3FX (United Kingdom); Li, Baojiu, E-mail: lucas.lombriser@port.ac.uk, E-mail: kazuya.koyama@port.ac.uk, E-mail: baojiu.li@durham.ac.uk [Institute for Computational Cosmology, Ogden Centre for Fundamental Physics, Department of Physics, University of Durham, Science Laboratories, South Road, Durham, DH1 3LE (United Kingdom)

    2014-03-01

    We analyse modelling techniques for the large-scale structure formed in scalar-tensor theories of constant Brans-Dicke parameter which match the concordance model background expansion history and produce a chameleon suppression of the gravitational modification in high-density regions. Thereby, we use a mass and environment dependent chameleon spherical collapse model, the Sheth-Tormen halo mass function and linear halo bias, the Navarro-Frenk-White halo density profile, and the halo model. Furthermore, using the spherical collapse model, we extrapolate a chameleon mass-concentration scaling relation from a ΛCDM prescription calibrated to N-body simulations. We also provide constraints on the model parameters to ensure viability on local scales. We test our description of the halo mass function and nonlinear matter power spectrum against the respective observables extracted from large-volume and high-resolution N-body simulations in the limiting case of f(R) gravity, corresponding to a vanishing Brans-Dicke parameter. We find good agreement between the two; the halo model provides a good qualitative description of the shape of the relative enhancement of the f(R) matter power spectrum with respect to ΛCDM caused by the extra attractive gravitational force but fails to recover the correct amplitude. Introducing an effective linear power spectrum in the computation of the two-halo term to account for an underestimation of the chameleon suppression at intermediate scales in our approach, we accurately reproduce the measurements from the N-body simulations.

  2. Galaxy power spectrum in redshift space: Combining perturbation theory with the halo model

    Science.gov (United States)

    Okumura, Teppei; Hand, Nick; Seljak, Uroš; Vlah, Zvonimir; Desjacques, Vincent

    2015-11-01

    Theoretical modeling of the redshift-space power spectrum of galaxies is crucially important to correctly extract cosmological information from galaxy redshift surveys. The task is complicated by the nonlinear biasing and redshift space distortion (RSD) effects, which change with halo mass, and by the wide distribution of halo masses and their occupations by galaxies. One of the main modeling challenges is the existence of satellite galaxies that have both radial distribution inside the halos and large virial velocities inside halos, a phenomenon known as the Finger-of-God (FoG) effect. We present a model for the redshift-space power spectrum of galaxies in which we decompose a given galaxy sample into central and satellite galaxies and relate different contributions to the power spectrum to 1-halo and 2-halo terms in a halo model. Our primary goal is to ensure that any parameters that we introduce have physically meaningful values, and are not just fitting parameters. For the lowest order 2-halo terms we use the previously developed RSD modeling of halos in the context of distribution function and perturbation theory approach. This term needs to be multiplied by the effect of radial distances and velocities of satellites inside the halo. To this one needs to add the 1-halo terms, which are nonperturbative. We show that the real space 1-halo terms can be modeled as almost constant, with the finite extent of the satellites inside the halo inducing a small k2R2 term over the range of scales of interest, where R is related to the size of the halo given by its halo mass. We adopt a similar model for FoG in redshift space, ensuring that FoG velocity dispersion is related to the halo mass. For FoG k2 type expansions do not work over the range of scales of interest and FoG resummation must be used instead. We test several simple damping functions to model the velocity dispersion FoG effect. Applying the formalism to mock galaxies modeled after the "CMASS" sample of the

  3. Sources of machine-induced background in the ATLAS and CMS detectors at the CERN Large Hadron Collider

    Energy Technology Data Exchange (ETDEWEB)

    Bruce, R., E-mail: roderik.bruce@cern.ch [CERN, Geneva (Switzerland); Assmann, R.W. [DESY, Hamburg (Germany); Boccone, V.; Bregliozzi, G.; Burkhardt, H.; Cerutti, F.; Ferrari, A.; Huhtinen, M.; Lechner, A.; Levinsen, Y.; Mereghetti, A. [CERN, Geneva (Switzerland); Mokhov, N.V.; Tropin, I.S. [FNAL, Batavia, IL 60510 (United States); Vlachoudis, V. [CERN, Geneva (Switzerland)

    2013-11-21

    One source of experimental background in the CERN Large Hadron Collider (LHC) is particles entering the detectors from the machine. These particles are created in cascades, caused by upstream interactions of beam protons with residual gas molecules or collimators. We estimate the losses on the collimators with SixTrack and simulate the showers with FLUKA and MARS to obtain the flux and distribution of particles entering the ATLAS and CMS detectors. We consider some machine configurations used in the first LHC run, with focus on 3.5 TeV operation as in 2011. Results from FLUKA and MARS are compared and a very good agreement is found. An analysis of logged LHC data provides, for different processes, absolute beam loss rates, which are used together with further simulations of vacuum conditions to normalize the results to rates of particles entering the detectors. We assess the relative importance of background from elastic and inelastic beam–gas interactions, and the leakage out of the LHC collimation system, and show that beam–gas interactions are the dominating source of machine-induced background for the studied machine scenarios. Our results serve as a starting point for the experiments to perform further simulations in order to estimate the resulting signals in the detectors. -- Highlights: •We simulate sources of machine-induced experimental background at the CERN LHC. •We focus on the ATLAS and CMS experiments. •The LHC machine conditions are analyzed to normalize the simulation results. •Beam–gas interactions is found to be the dominating source of particles entering the detectors.

  4. Simulating and Detecting Radiation-Induced Errors for Onboard Machine Learning

    Science.gov (United States)

    Wagstaff, Kiri L.; Bornstein, Benjamin; Granat, Robert; Tang, Benyang; Turmon, Michael

    2009-01-01

    Spacecraft processors and memory are subjected to high radiation doses and therefore employ radiation-hardened components. However, these components are orders of magnitude more expensive than typical desktop components, and they lag years behind in terms of speed and size. We have integrated algorithm-based fault tolerance (ABFT) methods into onboard data analysis algorithms to detect radiation-induced errors, which ultimately may permit the use of spacecraft memory that need not be fully hardened, reducing cost and increasing capability at the same time. We have also developed a lightweight software radiation simulator, BITFLIPS, that permits evaluation of error detection strategies in a controlled fashion, including the specification of the radiation rate and selective exposure of individual data structures. Using BITFLIPS, we evaluated our error detection methods when using a support vector machine to analyze data collected by the Mars Odyssey spacecraft. We found ABFT error detection for matrix multiplication is very successful, while error detection for Gaussian kernel computation still has room for improvement.

  5. A Brain-Machine Interface for Control of Medically-Induced Coma

    Science.gov (United States)

    Liberman, Max; Solt, Ken; Brown, Emery N.

    2013-01-01

    Medically-induced coma is a drug-induced state of profound brain inactivation and unconsciousness used to treat refractory intracranial hypertension and to manage treatment-resistant epilepsy. The state of coma is achieved by continually monitoring the patient's brain activity with an electroencephalogram (EEG) and manually titrating the anesthetic infusion rate to maintain a specified level of burst suppression, an EEG marker of profound brain inactivation in which bursts of electrical activity alternate with periods of quiescence or suppression. The medical coma is often required for several days. A more rational approach would be to implement a brain-machine interface (BMI) that monitors the EEG and adjusts the anesthetic infusion rate in real time to maintain the specified target level of burst suppression. We used a stochastic control framework to develop a BMI to control medically-induced coma in a rodent model. The BMI controlled an EEG-guided closed-loop infusion of the anesthetic propofol to maintain precisely specified dynamic target levels of burst suppression. We used as the control signal the burst suppression probability (BSP), the brain's instantaneous probability of being in the suppressed state. We characterized the EEG response to propofol using a two-dimensional linear compartment model and estimated the model parameters specific to each animal prior to initiating control. We derived a recursive Bayesian binary filter algorithm to compute the BSP from the EEG and controllers using a linear-quadratic-regulator and a model-predictive control strategy. Both controllers used the estimated BSP as feedback. The BMI accurately controlled burst suppression in individual rodents across dynamic target trajectories, and enabled prompt transitions between target levels while avoiding both undershoot and overshoot. The median performance error for the BMI was 3.6%, the median bias was -1.4% and the overall posterior probability of reliable control was 1 (95

  6. Galaxy models with live halos

    CERN Document Server

    Sellwood, J A

    1980-01-01

    Computer models of galaxies are described, in which the disc stars and the halo stars are both treated fully self consistently. These were used to test the validity of the 'rigid halo' approximation usually employed when studying the instabilities of a disc of stars. The models show that very little interaction between the populations occurs while the disc remains nearly axisymmetric, but a strong bar is able to transfer angular momentum from the disc to the halo. The global bar stability of the disc is not greatly affected by the interaction between the two stellar populations, and it is found that a large fraction of the total galactic mass is still required in the spheroidal component if bar formation is to be prevented. (36 refs).

  7. Halo-free Phase Contrast Microscopy

    National Research Council Canada - National Science Library

    Tan H Nguyen; Mikhail Kandel; Haadi M Shakir; Catherine Best-popescu; Jyothi Arikkath; Minh N Do; Gabriel Popescu

    2017-01-01

    We present a new approach for retrieving halo-free phase contrast microscopy (hfPC) images by upgrading the conventional PC microscope with an external interferometric module, which generates sufficient data for reversing the halo artifact...

  8. Visibility of halos and rainbows.

    Science.gov (United States)

    Gedzelman, S D

    1980-09-15

    A theory for the visibility of halos and rainbows is presented. The light reaching the observer's eye from the direction of the halo or rainbow is assumed to consist of two parts: (1) a beam of singly scattered sunlight (or moonlight) from a cloud of ice crystals or a rainswath, which, in turn, has suffered depletion by scattering or absorption in its passage to the observer, and (2) the general background brightness. The model is able to account for several long-known qualitative observations concerning halos, namely, that the brightest halos are produced by optically thin cirrostratus clouds (i.e., for which the cloud optical depth tau(c), rainbow the brightness of the beam increases monotonically with the optical depth tau(R) of the sunlit part of the rainswath, but the increase is quite small for tau(R) >/=1. On the other hand, the brightness of the background increases more rapidly with tau(R) for tau(R)> 1 so that the rainbow appears most easily visible for tau(R) less, similar1. This implies that the most easily visible rainbows are produced by light or moderate showers rather than heavy downpours. Finally, suggestions are made for applying the theory to other atmospheric optical phenomena, such as coronas and glories.

  9. Sources of machine-induced background in the ATLAS and CMS detectors at the CERN Large Hadron Collider

    Energy Technology Data Exchange (ETDEWEB)

    Bruce, R.; et al.,

    2013-11-21

    One source of experimental background in the CERN Large Hadron Collider (LHC) is particles entering the detectors from the machine. These particles are created in cascades, caused by upstream interactions of beam protons with residual gas molecules or collimators. We estimate the losses on the collimators with SixTrack and simulate the showers with FLUKA and MARS to obtain the flux and distribution of particles entering the ATLAS and CMS detectors. We consider some machine configurations used in the first LHC run, with focus on 3.5 TeV operation as in 2011. Results from FLUKA and MARS are compared and a very good agreement is found. An analysis of logged LHC data provides, for different processes, absolute beam loss rates, which are used together with further simulations of vacuum conditions to normalize the results to rates of particles entering the detectors. We assess the relative importance of background from elastic and inelastic beam-gas interactions, and the leakage out of the LHC collimation system, and show that beam-gas interactions are the dominating source of machine-induced background for the studied machine scenarios. Our results serve as a starting point for the experiments to perform further simulations in order to estimate the resulting signals in the detectors.

  10. Sources of machine-induced background in the ATLAS and CMS detectors at the CERN Large Hadron Collider

    Science.gov (United States)

    Bruce, R.; Assmann, R. W.; Boccone, V.; Bregliozzi, G.; Burkhardt, H.; Cerutti, F.; Ferrari, A.; Huhtinen, M.; Lechner, A.; Levinsen, Y.; Mereghetti, A.; Mokhov, N. V.; Tropin, I. S.; Vlachoudis, V.

    2013-11-01

    One source of experimental background in the CERN Large Hadron Collider (LHC) is particles entering the detectors from the machine. These particles are created in cascades, caused by upstream interactions of beam protons with residual gas molecules or collimators. We estimate the losses on the collimators with SixTrack and simulate the showers with FLUKA and MARS to obtain the flux and distribution of particles entering the ATLAS and CMS detectors. We consider some machine configurations used in the first LHC run, with focus on 3.5 TeV operation as in 2011. Results from FLUKA and MARS are compared and a very good agreement is found. An analysis of logged LHC data provides, for different processes, absolute beam loss rates, which are used together with further simulations of vacuum conditions to normalize the results to rates of particles entering the detectors. We assess the relative importance of background from elastic and inelastic beam-gas interactions, and the leakage out of the LHC collimation system, and show that beam-gas interactions are the dominating source of machine-induced background for the studied machine scenarios. Our results serve as a starting point for the experiments to perform further simulations in order to estimate the resulting signals in the detectors.

  11. ADMET Evaluation in Drug Discovery. 18. Reliable Prediction of Chemical-Induced Urinary Tract Toxicity by Boosting Machine Learning Approaches.

    Science.gov (United States)

    Lei, Tailong; Sun, Huiyong; Kang, Yu; Zhu, Feng; Liu, Hui; Zhou, Wenfang; Wang, Zhe; Li, Dan; Li, Youyong; Hou, Tingjun

    2017-11-06

    Xenobiotic chemicals and their metabolites are mainly excreted out of our bodies by the urinary tract through the urine. Chemical-induced urinary tract toxicity is one of the main reasons that cause failure during drug development, and it is a common adverse event for medications, natural supplements, and environmental chemicals. Despite its importance, there are only a few in silico models for assessing urinary tract toxicity for a large number of compounds with diverse chemical structures. Here, we developed a series of qualitative and quantitative structure-activity relationship (QSAR) models for predicting urinary tract toxicity. In our study, the recursive feature elimination method incorporated with random forests (RFE-RF) was used for dimension reduction, and then eight machine learning approaches were used for QSAR modeling, i.e., relevance vector machine (RVM), support vector machine (SVM), regularized random forest (RRF), C5.0 trees, eXtreme gradient boosting (XGBoost), AdaBoost.M1, SVM boosting (SVMBoost), and RVM boosting (RVMBoost). For building classification models, the synthetic minority oversampling technique was used to handle the imbalance data set problem. Among all the machine learning approaches, SVMBoost based on the RBF kernel achieves both the best quantitative (qext2 = 0.845) and qualitative predictions for the test set (MCC of 0.787, AUC of 0.893, sensitivity of 89.6%, specificity of 94.1%, and global accuracy of 90.8%). The application domains were then analyzed, and all of the tested chemicals fall within the application domain coverage. We also examined the structure features of the chemicals with large prediction errors. In brief, both the regression and classification models developed by the SVMBoost approach have reliable prediction capability for assessing chemical-induced urinary tract toxicity.

  12. Stability of machining induced residual stresses in Inconel 718 under quasi-static loading at room temperature

    Energy Technology Data Exchange (ETDEWEB)

    Madariaga, A., E-mail: amadariaga@mondragon.edu [Mechanical and Industrial Production Department, Faculty of Engineering, Mondragon Unibertsitatea, Loramendi 4, Mondragon 20500 Gipuzkoa (Spain); Esnaola, J.A.; Arrazola, P.J. [Mechanical and Industrial Production Department, Faculty of Engineering, Mondragon Unibertsitatea, Loramendi 4, Mondragon 20500 Gipuzkoa (Spain); Ruiz-Hervias, J.; Muñoz, P. [Departamento Ciencia de Materiales, ETSI Caminos, Universidad Politécnica de Madrid, c/Profesor Aranguren s/n, Madrid 28040 (Spain); Ostolaza, K. [Materials and Processes Technology Department, ITP S.A., Parque Tecnológico, Edificio 300, 48170 Zamudio (Spain)

    2015-01-03

    Tensile residual stresses are very often generated on the surface when machining nickel alloys. In order to determine their influence on the final mechanical behaviour of the component residual stress stability should be considered. In the present work the evolution of surface residual stresses induced by machining in Inconel 718 under static loading at room temperature was studied experimentally and numerically. An Inconel 718 disc was face turned employing industrial working conditions and specimens for tensile tests were extracted from the disc. Surface residual stresses were measured by X-ray diffraction for initial state and after applying different loads over the material's yield stress. Then, a finite element model based on the surface–core approach was fitted to experimental results and the study was extended to analyse the influence of load level, degree of work-hardening and initial surface conditions. For the studied case, initial tensile surface residual stress (776 MPa) became even more tensile when applying loads higher than the material yield stress, but a shift was observed at the highest applied load (1350 MPa) and initial residual stress was relaxed about 170 MPa. This particular behaviour is associated to the modified stress–strain properties of the machined affected surface layer which was strongly work-hardened. Moreover, if the work-hardened properties are not considered in the finite element model results differ substantially from experiments. Surface residual stress stability also depends on the initial surface residual stress, but the degree of work-hardening induced by the machining process must be considered as well. If the difference between the yield stress of the surface and the yield stress of the core is lower than the initial surface residual stress, the surface begins yielding first and consequently the surface residual stress is decreased. In contrast, if the difference between the yield stress of the surface and the

  13. Surface Finish and Residual Stresses Induced by Orthogonal Dry Machining of AA7075-T651.

    Science.gov (United States)

    Jomaa, Walid; Songmene, Victor; Bocher, Philippe

    2014-02-28

    The surface finish was extensively studied in usual machining processes (turning, milling, and drilling). For these processes, the surface finish is strongly influenced by the cutting feed and the tool nose radius. However, a basic understanding of tool/surface finish interaction and residual stress generation has been lacking. This paper aims to investigate the surface finish and residual stresses under the orthogonal cutting since it can provide this information by avoiding the effect of the tool nose radius. The orthogonal machining of AA7075-T651 alloy through a series of cutting experiments was performed under dry conditions. Surface finish was studied using height and amplitude distribution roughness parameters. SEM and EDS were used to analyze surface damage and built-up edge (BUE) formation. An analysis of the surface topography showed that the surface roughness was sensitive to changes in cutting parameters. It was found that the formation of BUE and the interaction between the tool edge and the iron-rich intermetallic particles play a determinant role in controlling the surface finish during dry orthogonal machining of the AA7075-T651 alloy. Hoop stress was predominantly compressive on the surface and tended to be tensile with increased cutting speed. The reverse occurred for the surface axial stress. The smaller the cutting feed, the greater is the effect of cutting speed on both axial and hoop stresses. By controlling the cutting speed and feed, it is possible to generate a benchmark residual stress state and good surface finish using dry machining.

  14. Galaxy and Mass Assembly (GAMA): halo formation times and halo assembly bias on the cosmic web

    Science.gov (United States)

    Tojeiro, Rita; Eardley, Elizabeth; Peacock, John A.; Norberg, Peder; Alpaslan, Mehmet; Driver, Simon P.; Henriques, Bruno; Hopkins, Andrew M.; Kafle, Prajwal R.; Robotham, Aaron S. G.; Thomas, Peter; Tonini, Chiara; Wild, Vivienne

    2017-09-01

    We present evidence for halo assembly bias as a function of geometric environment (GE). By classifying Galaxy and Mass Assembly (GAMA) galaxy groups as residing in voids, sheets, filaments or knots using a tidal tensor method, we find that low-mass haloes that reside in knots are older than haloes of the same mass that reside in voids. This result provides direct support to theories that link strong halo tidal interactions with halo assembly times. The trend with GE is reversed at large halo mass, with haloes in knots being younger than haloes of the same mass in voids. We find a clear signal of halo downsizing - more massive haloes host galaxies that assembled their stars earlier. This overall trend holds independently of GE. We support our analysis with an in-depth exploration of the L-Galaxies semi-analytic model, used here to correlate several galaxy properties with three different definitions of halo formation time. We find a complex relationship between halo formation time and galaxy properties, with significant scatter. We confirm that stellar mass to halo mass ratio, specific star formation rate (SFR) and mass-weighed age are reasonable proxies of halo formation time, especially at low halo masses. Instantaneous SFR is a poor indicator at all halo masses. Using the same semi-analytic model, we create mock spectral observations using complex star formation and chemical enrichment histories, which approximately mimic GAMA's typical signal-to-noise ratio and wavelength range. We use these mocks to assert how well potential proxies of halo formation time may be recovered from GAMA-like spectroscopic data.

  15. Measurement-induced operation of two-ion quantum heat machines

    Science.gov (United States)

    Chand, Suman; Biswas, Asoka

    2017-03-01

    We show how one can implement a quantum heat machine by using two interacting trapped ions, in presence of a thermal bath. The electronic states of the ions act like a working substance, while the vibrational mode is modelled as the cold bath. The heat exchange with the cold bath is mimicked by the projective measurement of the electronic states. We show how such measurement in a suitable basis can lead to either a quantum heat engine or a refrigerator, which undergoes a quantum Otto cycle. The local magnetic field is adiabatically changed during the heat cycle. The performance of the heat machine depends upon the interaction strength between the ions, the magnetic fields, and the measurement cost. In our model, the coupling to the hot and the cold baths is never switched off in an alternative fashion during the heat cycle, unlike other existing proposals of quantum heat engines. This makes our proposal experimentally realizable using current tapped-ion technology.

  16. Unbound particles in dark matter halos

    Energy Technology Data Exchange (ETDEWEB)

    Behroozi, Peter S.; Loeb, Abraham; Wechsler, Risa H.

    2013-06-13

    We investigate unbound dark matter particles in halos by tracing particle trajectories in a simulation run to the far future (a = 100). We find that the traditional sum of kinetic and potential energies is a very poor predictor of which dark matter particles will eventually become unbound from halos. We also study the mass fraction of unbound particles, which increases strongly towards the edges of halos, and decreases significantly at higher redshifts. We discuss implications for dark matter detection experiments, precision calibrations of the halo mass function, the use of baryon fractions to constrain dark energy, and searches for intergalactic supernovae.

  17. Halo scale predictions of symmetron modified gravity

    Energy Technology Data Exchange (ETDEWEB)

    Clampitt, Joseph; Jain, Bhuvnesh; Khoury, Justin, E-mail: clampitt@sas.upenn.edu, E-mail: bjain@physics.upenn.edu, E-mail: jkhoury@sas.upenn.edu [Center for Particle Cosmology and Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd St., Philadelphia, PA 19104 (United States)

    2012-01-01

    We offer predictions of symmetron modified gravity in the neighborhood of realistic dark matter halos. The predictions for the fifth force are obtained by solving the nonlinear symmetron equation of motion in the spherical NFW approximation. In addition, we compare the three major known screening mechanisms: Vainshtein, Chameleon, and Symmetron around such dark matter halos, emphasizing the significant differences between them and highlighting observational tests which exploit these differences. Finally, we demonstrate the host halo environmental screening effect (''blanket screening'') on smaller satellite halos by solving for the modified forces around a density profile which is the sum of satellite and approximate host components.

  18. Surface Finish and Residual Stresses Induced by Orthogonal Dry Machining of AA7075-T651

    Directory of Open Access Journals (Sweden)

    Walid Jomaa

    2014-02-01

    Full Text Available The surface finish was extensively studied in usual machining processes (turning, milling, and drilling. For these processes, the surface finish is strongly influenced by the cutting feed and the tool nose radius. However, a basic understanding of tool/surface finish interaction and residual stress generation has been lacking. This paper aims to investigate the surface finish and residual stresses under the orthogonal cutting since it can provide this information by avoiding the effect of the tool nose radius. The orthogonal machining of AA7075-T651 alloy through a series of cutting experiments was performed under dry conditions. Surface finish was studied using height and amplitude distribution roughness parameters. SEM and EDS were used to analyze surface damage and built-up edge (BUE formation. An analysis of the surface topography showed that the surface roughness was sensitive to changes in cutting parameters. It was found that the formation of BUE and the interaction between the tool edge and the iron-rich intermetallic particles play a determinant role in controlling the surface finish during dry orthogonal machining of the AA7075-T651 alloy. Hoop stress was predominantly compressive on the surface and tended to be tensile with increased cutting speed. The reverse occurred for the surface axial stress. The smaller the cutting feed, the greater is the effect of cutting speed on both axial and hoop stresses. By controlling the cutting speed and feed, it is possible to generate a benchmark residual stress state and good surface finish using dry machining.

  19. Labelling HaloTag Fusion Proteins with HaloTag Ligand in Living Cells.

    Science.gov (United States)

    Duc, Huy Nguyen; Ren, Xiaojun

    2017-09-05

    HaloTag has been widely used to label proteins in vitro and in vivo (Los et al., 2008). In this protocol, we describe labelling HaloTag-Cbx fusion proteins by HaloTag ligands for live-cell single-molecule imaging (Zhen et al., 2016).

  20. Labelling HaloTag Fusion Proteins with HaloTag Ligand in Living Cells

    OpenAIRE

    Duc, Huy Nguyen; Ren, Xiaojun

    2017-01-01

    HaloTag has been widely used to label proteins in vitro and in vivo (Los et al., 2008). In this protocol, we describe labelling HaloTag-Cbx fusion proteins by HaloTag ligands for live-cell single-molecule imaging (Zhen et al., 2016).

  1. UARS Halogen Occultation Experiment (HALOE) Level 2 V001

    Data.gov (United States)

    National Aeronautics and Space Administration — The HALOE home page on the WWW is http://haloe.gats-inc.com/home/index.php The Halogen Occultation Experiment (HALOE) on NASA's Upper Atmosphere Research Satellite...

  2. Studying dark matter haloes with weak lensing

    NARCIS (Netherlands)

    Velander, Malin Barbro Margareta

    2012-01-01

    Our Universe is comprised not only of normal matter but also of unknown components: dark matter and dark energy. This Thesis recounts studies of dark matter haloes, using a technique known as weak gravitational lensing, in order to learn more about the nature of these dark components. The haloes

  3. Halo abundances and shear in void models

    DEFF Research Database (Denmark)

    Alonso, David; García-Bellido, Juan; Haugbølle, Troels

    2012-01-01

    We study the non-linear gravitational collapse of dark matter into halos through numerical N-body simulations of Lemaitre-Tolman-Bondi void models. We extend the halo mass function formalism to these models in a consistent way. This extension not only compares well with the simulated data at all...

  4. MODIFIED DYNAMICS (MOND) AS A DARK HALO

    NARCIS (Netherlands)

    SANDERS, RH; BEGEMAN, KG

    1994-01-01

    We propose a form for dark haloes that embodies the fundamental aspect of Milgrom's modified dynamics (MOND): the discrepancy between the visible mass and the Newtonian dynamical mass appears below a critical acceleration. This is a halo having a density distribution, at least to several tens of

  5. Galactic stellar haloes in the CDM model

    NARCIS (Netherlands)

    Cooper, A. P.; Cole, S.; Frenk, C. S.; White, S. D. M.; Helly, J.; Benson, A. J.; De Lucia, G.; Helmi, A.; Jenkins, A.; Navarro, J. F.; Springel, V.; Wang, J.

    2010-01-01

    We present six simulations of galactic stellar haloes formed by the tidal disruption of accreted dwarf galaxies in a fully cosmological setting. Our model is based on the Aquarius project, a suite of high-resolution N-body simulations of individual dark matter haloes. We tag subsets of particles in

  6. Integrating Machine Learning into a Crowdsourced Model for Earthquake-Induced Damage Assessment

    Science.gov (United States)

    Rebbapragada, Umaa; Oommen, Thomas

    2011-01-01

    On January 12th, 2010, a catastrophic 7.0M earthquake devastated the country of Haiti. In the aftermath of an earthquake, it is important to rapidly assess damaged areas in order to mobilize the appropriate resources. The Haiti damage assessment effort introduced a promising model that uses crowdsourcing to map damaged areas in freely available remotely-sensed data. This paper proposes the application of machine learning methods to improve this model. Specifically, we apply work on learning from multiple, imperfect experts to the assessment of volunteer reliability, and propose the use of image segmentation to automate the detection of damaged areas. We wrap both tasks in an active learning framework in order to shift volunteer effort from mapping a full catalog of images to the generation of high-quality training data. We hypothesize that the integration of machine learning into this model improves its reliability, maintains the speed of damage assessment, and allows the model to scale to higher data volumes.

  7. WFIRST: Surveying galactic halos within 10Mpc

    Science.gov (United States)

    Courtney, Sol; Johnston, Kathryn; Sanderson, Robyn; WINGS Team

    2018-01-01

    Three aims of a WFIRST Infrared Nearby Galaxy Survey (WINGS) of stellar halos are: (i) to look at the global properties of the halos (e.g. radial profile and total content); (ii) to find and interpret structures that are signatures of accretion histories (including luminosity functions, merger rates and orbits); (iii) to find features at widest possible separations in order to constrain the distribution of dark matter. For all of the above purposes, the halos should be observed to the greatest radial extent possible. The extent to which this is possible or interesting will depend on expected densities of the stellar halos as well as contamination by background galaxies at faint magnitudes. This study “observes" the Bullock/Johnston stellar halo models as a guide for these expectations.

  8. Measurements of beam halo diffusion and population density in the Tevatron and in the Large Hadron Collider

    CERN Document Server

    Stancari, Giulio

    Halo dynamics influences global accelerator performance: beam lifetimes, emittance growth, dynamic aperture, and collimation efficiency. Halo monitoring and control are also critical for the operation of high-power machines. For instance, in the high-luminosity upgrade of the LHC, the energy stored in the beam tails may reach several megajoules. Fast losses can result in superconducting magnet quenches, magnet damage, or even collimator deformation. The need arises to measure the beam halo and to remove it at controllable rates. In the Tevatron and in the LHC, halo population densities and diffusivities were measured with collimator scans by observing the time evolution of losses following small inward or outward collimator steps, under different experimental conditions: with single beams and in collision, and, in the case of the Tevatron, with a hollow electron lens acting on a subset of bunches. After the LHC resumes operations, it is planned to compare measured diffusivities with the known strength of tran...

  9. Design of CMS Beam Halo Monitor system

    CERN Document Server

    AUTHOR|(CDS)2078842

    2015-01-01

    A fast and directional monitoring system for the CMS experiment is designed to provide an online, bunch-by-bunch measurement of beam background induced by beam halo interactions, separately for each beam. The background detection is based on Cherenkov radiation produced in synthetic fused silica read out by a fast, UV sensitive photomultiplier tube. Twenty detector units per end will be azimuthally distributed around the rotating shielding of CMS, covering ~408 cm2 at 20.6m from the interaction point, at a radius of ~180 cm. The directional and fast response of the system allows the discrimination of the background particles from the dominant flux in the cavern induced by pp collision debris, produced within the 25 ns bunch spacing. A robust multi-layered shielding will enclose each detector unit to protect the photomultiplier tube from the magnetic field and to eliminate the occupancy from low energy particles. The design of the front-end units is validated by experimental results. An overview of the new sy...

  10. Halo assembly bias and the tidal anisotropy of the local halo environment

    Science.gov (United States)

    Paranjape, Aseem; Hahn, Oliver; Sheth, Ravi K.

    2018-02-01

    We study the role of the local tidal environment in determining the assembly bias of dark matter haloes. Previous results suggest that the anisotropy of a halo's environment (i.e, whether it lies in a filament or in a more isotropic region) can play a significant role in determining the eventual mass and age of the halo. We statistically isolate this effect using correlations between the large-scale and small-scale environments of simulated haloes at z = 0 with masses between 1011.6 ≲ (m/h-1M⊙) ≲ 1014.9. We probe the large-scale environment using a novel halo-by-halo estimator of linear bias. For the small-scale environment, we identify a variable αR that captures the tidal anisotropy in a region of radius R = 4R200b around the halo and correlates strongly with halo bias at fixed mass. Segregating haloes by αR reveals two distinct populations. Haloes in highly isotropic local environments (αR ≲ 0.2) behave as expected from the simplest, spherically averaged analytical models of structure formation, showing a negative correlation between their concentration and large-scale bias at all masses. In contrast, haloes in anisotropic, filament-like environments (αR ≳ 0.5) tend to show a positive correlation between bias and concentration at any mass. Our multi-scale analysis cleanly demonstrates how the overall assembly bias trend across halo mass emerges as an average over these different halo populations, and provides valuable insights towards building analytical models that correctly incorporate assembly bias. We also discuss potential implications for the nature and detectability of galaxy assembly bias.

  11. Dark matter haloes: a multistream view

    Science.gov (United States)

    Ramachandra, Nesar S.; Shandarin, Sergei F.

    2017-09-01

    Mysterious dark matter constitutes about 85 per cent of all masses in the Universe. Clustering of dark matter plays a dominant role in the formation of all observed structures on scales from a fraction to a few hundreds of Mega-parsecs. Galaxies play a role of lights illuminating these structures so they can be observed. The observations in the last several decades have unveiled opulent geometry of these structures currently known as the cosmic web. Haloes are the highest concentrations of dark matter and host luminous galaxies. Currently the most accurate modelling of dark matter haloes is achieved in cosmological N-body simulations. Identifying the haloes from the distribution of particles in N-body simulations is one of the problems attracting both considerable interest and efforts. We propose a novel framework for detecting potential dark matter haloes using the field unique for dark matter-multistream field. The multistream field emerges at the non-linear stage of the growth of perturbations because the dark matter is collisionless. Counting the number of velocity streams in gravitational collapses supplements our knowledge of spatial clustering. We assume that the virialized haloes have convex boundaries. Closed and convex regions of the multistream field are hence isolated by imposing a positivity condition on all three eigenvalues of the Hessian estimated on the smoothed multistream field. In a single-scale analysis of high multistream field resolution and low softening length, the halo substructures with local multistream maxima are isolated as individual halo sites.

  12. Effective field theory description of halo nuclei

    Science.gov (United States)

    Hammer, H.-W.; Ji, C.; Phillips, D. R.

    2017-10-01

    Nuclear halos emerge as new degrees of freedom near the neutron and proton driplines. They consist of a core and one or a few nucleons which spend most of their time in the classically-forbidden region outside the range of the interaction. Individual nucleons inside the core are thus unresolved in the halo configuration, and the low-energy effective interactions are short-range forces between the core and the valence nucleons. Similar phenomena occur in clusters of 4He atoms, cold atomic gases near a Feshbach resonance, and some exotic hadrons. In these weakly-bound quantum systems universal scaling laws for s-wave binding emerge that are independent of the details of the interaction. Effective field theory (EFT) exposes these correlations and permits the calculation of non-universal corrections to them due to short-distance effects, as well as the extension of these ideas to systems involving the Coulomb interaction and/or binding in higher angular-momentum channels. Halo nuclei exhibit all these features. Halo EFT, the EFT for halo nuclei, has been used to compute the properties of single-neutron, two-neutron, and single-proton halos of s-wave and p-wave type. This review summarizes these results for halo binding energies, radii, Coulomb dissociation, and radiative capture, as well as the connection of these properties to scattering parameters, thereby elucidating the universal correlations between all these observables. We also discuss how Halo EFT's encoding of the long-distance physics of halo nuclei can be used to check and extend ab initio calculations that include detailed modeling of their short-distance dynamics.

  13. Prediction of drug-induced nephrotoxicity and injury mechanisms with human induced pluripotent stem cell-derived cells and machine learning methods.

    Science.gov (United States)

    Kandasamy, Karthikeyan; Chuah, Jacqueline Kai Chin; Su, Ran; Huang, Peng; Eng, Kim Guan; Xiong, Sijing; Li, Yao; Chia, Chun Siang; Loo, Lit-Hsin; Zink, Daniele

    2015-07-27

    The renal proximal tubule is a main target for drug-induced toxicity. The prediction of proximal tubular toxicity during drug development remains difficult. Any in vitro methods based on induced pluripotent stem cell-derived renal cells had not been developed, so far. Here, we developed a rapid 1-step protocol for the differentiation of human induced pluripotent stem cells (hiPSC) into proximal tubular-like cells. These proximal tubular-like cells had a purity of >90% after 8 days of differentiation and could be directly applied for compound screening. The nephrotoxicity prediction performance of the cells was determined by evaluating their responses to 30 compounds. The results were automatically determined using a machine learning algorithm called random forest. In this way, proximal tubular toxicity in humans could be predicted with 99.8% training accuracy and 87.0% test accuracy. Further, we studied the underlying mechanisms of injury and drug-induced cellular pathways in these hiPSC-derived renal cells, and the results were in agreement with human and animal data. Our methods will enable the development of personalized or disease-specific hiPSC-based renal in vitro models for compound screening and nephrotoxicity prediction.

  14. Performance evaluation of induced gas flotation (IGF) machine through math modeling

    Energy Technology Data Exchange (ETDEWEB)

    Leech, C.A. (Shell Dev. Co.); Hillyer, M.J.; Degner, V.R.; Radhakrishnan, S.

    1978-01-01

    Oil removal from actual produced water was studied in a full-scale four-cell IGF machine installed in the Shell Oil Co., Coalinga, Calif., oilfield. The oil removal rate was first order in concentration since the oil removal ratio was independent of inlet oil concentration. Tracer studies showed that perfect backmixing was approximated in each cell, so that oil removal kinetics could possibly be modeled as a first-order chemical reaction in a series of stirred tanks. The influential variables, in order of decreasing importance, were: water treating chemical concentration Vertical Bar3: flow rate Vertical Bar3:Vertical Bar3: rotor speed approx. rotor submergence approx. rotor engagement. Variables that had little effect on the oil removal ratio in the ranges studied were: rotor diameter, skim rate, and inlet oil concentration. Optimization results can be used to improve the operation of existing units of the same design flow rate and can possibly be scaled to other size units. Models derived for Coalinga lubricating crude in Coalinga-produced water should not be used to predict performance in other fields, since experience indicates that removal efficiency is a strong function of crude type and produced water.

  15. The HSP70 chaperone machines of Chlamydomonas are induced by cold stress.

    Science.gov (United States)

    Maikova, Anna; Zalutskaya, Zhanneta; Lapina, Tatiana; Ermilova, Elena

    2016-10-01

    The responses of Chlamydomonas reinhardtii cells to low temperatures have not been extensively studied compared with other stresses. Like other organisms, this green alga has heat shock protein 70s (HSP70s) that are located in chloroplast, mitochondrion and cytosol. To test whether temperature downshifts affected HSP70s synthesis, we used real-time PCR and protein gel blot analysis. C. reinhardtii cells exposed to cold stress show increased HSP70s mRNA levels. Genes encoding other components of HSP70 chaperone machines (e.g. CGE1, CDJ1, HSP90C and HSP90A) are also up-regulated in response to decreased temperature. We demonstrated that the accumulation of all analyzed mRNA occur more slowly and with reduced amplitude in cells exposed to cold than in cells treated with heat. Furthermore, C. reinhardtii cells display the splicing of the CGE1 transcript that was dependent on low temperature. Finally, the transcription regulator of C. reinhardtii HSF1 is also cold-responsive, suggesting its role in the transcriptional regulation of HSP genes at low temperature. Copyright © 2016 Elsevier GmbH. All rights reserved.

  16. Phosphate limitation induces the intergeneric inhibition of Pseudomonas aeruginosa by Serratia marcescens isolated from paper machines.

    Science.gov (United States)

    Kuo, Pei-An; Kuo, Chih-Horng; Lai, Yiu-Kay; Graumann, Peter L; Tu, Jenn

    2013-06-01

    Phosphate is an essential nutrient for heterotrophic bacteria, affecting bacterioplankton in aquatic ecosystems and bacteria in biofilms. However, the influence of phosphate limitation on bacterial competition and biofilm development in multispecies populations has received limited attention in existing studies. To address this issue, we isolated 13 adhesive bacteria from paper machine aggregates. Intergeneric inhibition of Pseudomonas aeruginosa WW5 by Serratia marcescens WW4 was identified under phosphate-limited conditions, but not in Luria-Bertani medium or M9 minimal medium. The viable numbers of the pure S. marcescens WW4 culture decreased over 3 days in the phosphate-limited medium; however, the mortality of S. marcescens WW4 was significantly reduced when it was co-cultured with P. aeruginosa WW5, which appeared to sustain the S. marcescens WW4 biofilm. In contrast, viable P. aeruginosa WW5 cells immediately declined in the phosphate-limited co-culture. To identify the genetic/inhibitory element(s) involved in this process, we inserted a mini-Tn5 mutant of S. marcescens WW4 that lacked inhibitory effect. The results showed that an endonuclease bacteriocin was involved in this intergeneric inhibition by S. marcescens WW4 under phosphate limitation. In conclusion, this study highlights the importance of nutrient limitation in bacterial interactions and provides a strong candidate gene for future functional characterisation. © 2013 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

  17. The Dark Halo of the Milky Way

    National Research Council Canada - National Science Library

    Charles Alcock

    2000-01-01

    .... This dark matter is distributed in space differently than the stars, forming a vast, diffuse halo, more spherical than disklike, which occupies more than 1000 times the volume of the disk of stars...

  18. Exact Relativistic Magnetized Haloes around Rotating Disks

    Directory of Open Access Journals (Sweden)

    Antonio C. Gutiérrez-Piñeres

    2015-01-01

    Full Text Available The study of the dynamics of magnetic fields in galaxies is one of important problems in formation and evolution of galaxies. In this paper, we present the exact relativistic treatment of a rotating disk surrounded by a magnetized material halo. The features of the halo and disk are described by the distributional energy-momentum tensor of a general fluid in canonical form. All the relevant quantities and the metric and electromagnetic potentials are exactly determined by an arbitrary harmonic function only. For instance, the generalized Kuzmin-disk potential is used. The particular class of solutions obtained is asymptotically flat and satisfies all the energy conditions. Moreover, the motion of a charged particle on the halo is described. As far as we know, this is the first relativistic model describing analytically the magnetized halo of a rotating disk.

  19. Simulating rainbows and halos in color.

    Science.gov (United States)

    Gedzelman, S D

    1994-07-20

    Geometric optics rainbows and ice-crystal halos that include some effects of a Rayleigh-scattering atmosphere and a cloud of finite optical thickness are simulated in color by the use of a Monte Carlo approach.

  20. Spatial Clustering of Dark Matter Haloes: Secondary Bias, Neighbour Bias, and the Influence of Massive Neighbours on Halo Properties

    Science.gov (United States)

    Salcedo, Andrés N.; Maller, Ariyeh H.; Berlind, Andreas A.; Sinha, Manodeep; McBride, Cameron K.; Behroozi, Peter S.; Wechsler, Risa H.; Weinberg, David H.

    2018-01-01

    We explore the phenomenon commonly known as halo assembly bias, whereby dark matter haloes of the same mass are found to be more or less clustered when a second halo property is considered, for haloes in the mass range 3.7 × 1011 h-1 M⊙ - 5.0 × 1013 h-1 M⊙. Using the Large Suite of Dark Matter Simulations (LasDamas) we consider nine commonly used halo properties and find that a clustering bias exists if haloes are binned by mass or by any other halo property. This secondary bias implies that no single halo property encompasses all the spatial clustering information of the halo population. The mean values of some halo properties depend on their halo's distance to a more massive neighbour. Halo samples selected by having high values of one of these properties therefore inherit a neighbour bias such that they are much more likely to be close to a much more massive neighbour. This neighbour bias largely accounts for the secondary bias seen in haloes binned by mass and split by concentration or age. However, haloes binned by other mass-like properties still show a secondary bias even when the neighbour bias is removed. The secondary bias of haloes selected by their spin behaves differently than that for other halo properties, suggesting that the origin of the spin bias is different than of other secondary biases.

  1. HaloTag, a Platform Technology for Protein Analysis.

    Science.gov (United States)

    Urh, Marjeta; Rosenberg, Martin

    2012-01-01

    Understanding protein function and interaction is central to the elucidation of biological processes. Systematic analysis of protein interactions have shown that the eukaryotic proteome is highly interconnected and that biological function frequently depends on the orchestrated action of many proteins. Perturbation of these functions or interactions can lead to various disease states and pharmacologic intervention can result in corrective therapies. The fact that proteins rarely act in isolation, but rather comprise complex machines that stably and/or transiently interact with many different partners at different times, demands the need for robust tools that allow comprehensive global analyses of these events. Here we describe a powerful protein fusion technology, the HaloTag platform, and how it enables the study of many facets of protein biology by offering a broad choice of applications. We review the development of the key aspects of the technology and it's performance in both in vitro and in vivo applications. In particular, we focus on HaloTag's multifunctional utility in protein imaging, protein isolation and display, and in the study of protein complexes and interactions. We demonstrate it's potential to help elucidate important facets of proteomic biology across complex biological systems at the biochemical, cell-based and whole animal level.

  2. MODIFIED GRAVITY SPINS UP GALACTIC HALOS

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jounghun [Astronomy Program, Department of Physics and Astronomy, FPRD, Seoul National University, Seoul 151-747 (Korea, Republic of); Zhao, Gong-Bo [National Astronomy Observatories, Chinese Academy of Science, Beijing 100012 (China); Li, Baojiu [Institute of Computational Cosmology, Department of Physics, Durham University, Durham DH1 3LE (United Kingdom); Koyama, Kazuya, E-mail: jounghun@astro.snu.ac.kr [Institute of Cosmology and Gravitation, University of Portsmouth, Portsmouth, PO1 3FX (United Kingdom)

    2013-01-20

    We investigate the effect of modified gravity on the specific angular momentum of galactic halos by analyzing the halo catalogs at z = 0 from high-resolution N-body simulations for a f(R) gravity model that meets the solar-system constraint. It is shown that the galactic halos in the f(R) gravity model tend to acquire significantly higher specific angular momentum than those in the standard {Lambda}CDM model. The largest difference in the specific angular momentum distribution between these two models occurs for the case of isolated galactic halos with mass less than 10{sup 11} h {sup -1} M {sub Sun }, which are likely least shielded by the chameleon screening mechanism. As the specific angular momentum of galactic halos is rather insensitive to other cosmological parameters, it can in principle be an independent discriminator of modified gravity. We speculate a possibility of using the relative abundance of low surface brightness galaxies (LSBGs) as a test of general relativity given that the formation of the LSBGs occurs in fast spinning dark halos.

  3. Nanomechanics of HaloTag tethers.

    Science.gov (United States)

    Popa, Ionel; Berkovich, Ronen; Alegre-Cebollada, Jorge; Badilla, Carmen L; Rivas-Pardo, Jaime Andrés; Taniguchi, Yukinori; Kawakami, Masaru; Fernandez, Julio M

    2013-08-28

    The active site of the Haloalkane Dehydrogenase (HaloTag) enzyme can be covalently attached to a chloroalkane ligand providing a mechanically strong tether, resistant to large pulling forces. Here we demonstrate the covalent tethering of protein L and I27 polyproteins between an atomic force microscopy (AFM) cantilever and a glass surface using HaloTag anchoring at one end and thiol chemistry at the other end. Covalent tethering is unambiguously confirmed by the observation of full length polyprotein unfolding, combined with high detachment forces that range up to ∼2000 pN. We use these covalently anchored polyproteins to study the remarkable mechanical properties of HaloTag proteins. We show that the force that triggers unfolding of the HaloTag protein exhibits a 4-fold increase, from 131 to 491 pN, when the direction of the applied force is changed from the C-terminus to the N-terminus. Force-clamp experiments reveal that unfolding of the HaloTag protein is twice as sensitive to pulling force compared to protein L and refolds at a slower rate. We show how these properties allow for the long-term observation of protein folding-unfolding cycles at high forces, without interference from the HaloTag tether.

  4. New views of the distant stellar halo

    Science.gov (United States)

    Sanderson, Robyn E.; Secunda, Amy; Johnston, Kathryn V.; Bochanski, John J.

    2017-10-01

    Currently, only a small number of Milky Way (MW) stars are known to exist beyond 100 kpc from the Galactic Centre. Though the distribution of these stars in the outer halo is believed to be sparse, they can provide evidence of more recent accretion events than in the inner halo and help map out the MW's dark matter halo to its virial radius. We have re-examined the outermost regions of 11 existing stellar halo models with two synthetic surveys: one mimicking present-day searches for distant M giants and another mimicking RR Lyra (RRL) projections for the Large Synoptic Survey Telescope (LSST). Our models suggest that colour and proper motion cuts currently used to select M giant candidates for follow-up successfully remove nearly all self-contamination from foreground halo dwarf stars and are useful for focusing observations on distant M giants, of which there are thousands to tens of thousands beyond 100 kpc in our models. We likewise expect that LSST will identify comparable numbers of RRLe at these distances. We demonstrate that several observable properties of both tracers, such as proximity of neighbouring stars, proper motions and distances (for RRLe), could help us separate different accreted dwarf galaxies from one another in the distant MW halo. We also discuss prospects for using ratios of M giants to RRLe as a proxy for accretion time, which in the future could provide new constraints on the recent accretion history of our Galaxy.

  5. RR Lyrae to understand the Galactic halo

    Science.gov (United States)

    Fiorentino, Giuliana

    2016-08-01

    We present recent results obtained using old variable RR Lyrae stars on the Galactic halo structure and its connection with nearby dwarf galaxies. We compare the period and period-amplitude distributions for a sizeable sample of fundamental mode RR Lyrae stars (RRab) in dwarf spheroidals (~1300 stars) with those in the Galactic halo (~16'000 stars) and globular clusters (~1000 stars). RRab in dwarfs -as observed today- do not appear to follow the pulsation properties shown by those in the Galactic halo, nor they have the same properties as RRab in globulars. Thanks to the OGLE experiment we extended our comparison to massive metal-rich satellites like the dwarf irregular Large Magellanic Cloud (LMC) and the Sagittarius (Sgr) dwarf spheroidal. These massive and more metal-rich stellar systems likely have contributed to the Galactic halo formation more than classical dwarf spheroidals. Finally, exploiting the intrinsic nature of RR Lyrae as distance indicators we were able to study the period and period amplitude distributions of RRab within the Halo. It turned out that the inner and the outer Halo do show a difference that may suggest a different formation scenario (in situ vs accreted).

  6. Parameterization of typhoon-induced ocean cooling using temperature equation and machine learning algorithms: an example of typhoon Soulik (2013)

    Science.gov (United States)

    Wei, Jun; Jiang, Guo-Qing; Liu, Xin

    2017-09-01

    This study proposed three algorithms that can potentially be used to provide sea surface temperature (SST) conditions for typhoon prediction models. Different from traditional data assimilation approaches, which provide prescribed initial/boundary conditions, our proposed algorithms aim to resolve a flow-dependent SST feedback between growing typhoons and oceans in the future time. Two of these algorithms are based on linear temperature equations (TE-based), and the other is based on an innovative technique involving machine learning (ML-based). The algorithms are then implemented into a Weather Research and Forecasting model for the simulation of typhoon to assess their effectiveness, and the results show significant improvement in simulated storm intensities by including ocean cooling feedback. The TE-based algorithm I considers wind-induced ocean vertical mixing and upwelling processes only, and thus obtained a synoptic and relatively smooth sea surface temperature cooling. The TE-based algorithm II incorporates not only typhoon winds but also ocean information, and thus resolves more cooling features. The ML-based algorithm is based on a neural network, consisting of multiple layers of input variables and neurons, and produces the best estimate of the cooling structure, in terms of its amplitude and position. Sensitivity analysis indicated that the typhoon-induced ocean cooling is a nonlinear process involving interactions of multiple atmospheric and oceanic variables. Therefore, with an appropriate selection of input variables and neuron sizes, the ML-based algorithm appears to be more efficient in prognosing the typhoon-induced ocean cooling and in predicting typhoon intensity than those algorithms based on linear regression methods.

  7. Machine Learning Approach to Automated Quality Identification of Human Induced Pluripotent Stem Cell Colony Images

    OpenAIRE

    Henry Joutsijoki; Markus Haponen; Jyrki Rasku; Katriina Aalto-Setälä; Martti Juhola

    2016-01-01

    The focus of this research is on automated identification of the quality of human induced pluripotent stem cell (iPSC) colony images. iPS cell technology is a contemporary method by which the patient’s cells are reprogrammed back to stem cells and are differentiated to any cell type wanted. iPS cell technology will be used in future to patient specific drug screening, disease modeling, and tissue repairing, for instance. However, there are technical challenges before iPS cell technology can b...

  8. Statistics of dark matter substructure - III. Halo-to-halo variance

    Science.gov (United States)

    Jiang, Fangzhou; van den Bosch, Frank C.

    2017-11-01

    We present a study of unprecedented statistical power regarding the halo-to-halo variance of dark matter substructure. Combining N-body simulations and a semi-analytical model, we investigate the variance in subhalo mass fractions and occupation numbers, with an emphasis on their halo-formation-time dependence. We show that the average subhalo mass fraction, fsub, is mainly a function of halo formation time: at fixed formation redshift, the average subhalo mass fraction is virtually independent of halo mass and the mass dependence of fsub therefore mainly manifests the later assembly of more massive haloes. We note that the observational constraints on fsub from gravitational lensing are substantially higher than the median Λcold dark matter predictions, yet marginally lie within the 95th percentile when the halo-to-halo variance is considered. The halo occupation number distribution of subhaloes, P(Nsub|Mhalo), in addition to the well-known super-Poissonity for large 〈Nsub〉, is sub-Poissonian for 〈Nsub〉 ≲ 2. Ignoring this results in systematic errors of the predicted clustering of galaxies of a few percent, with a complicated scale- and luminosity dependence. The non-Poissonity is likely imprinted at accretion, and the dynamical evolution of subhaloes drives the statistics towards Poissonian. Contrary to a recent claim, the non-Poissonity of subhalo occupation statistics does not vanish by selecting haloes with fixed mass and fixed formation redshift. Finally, we use subhalo occupation statistics to put loose constraints on the mass and formation redshift of the Milky Way halo.

  9. Simulating Halos with the Caterpillar Project

    Science.gov (United States)

    Kohler, Susanna

    2016-04-01

    The Caterpillar Project is a beautiful series of high-resolution cosmological simulations. The goal of this project is to examine the evolution of dark-matter halos like the Milky Ways, to learn about how galaxies like ours formed. This immense computational project is still in progress, but the Caterpillar team is already providing a look at some of its first results.Lessons from Dark-Matter HalosWhy simulate the dark-matter halos of galaxies? Observationally, the formation history of our galaxy is encoded in galactic fossil record clues, like the tidal debris from disrupted satellite galaxies in the outer reaches of our galaxy, or chemical abundance patterns throughout our galactic disk and stellar halo.But to interpret this information in a way that lets us learn about our galaxys history, we need to first test galaxy formation and evolution scenarios via cosmological simulations. Then we can compare the end result of these simulations to what we observe today.This figure illustrates the difference that mass resolution makes. In the left panel, the mass resolution is 1.5*10^7 solar masses per particle. In the right panel, the mass resolution is 3*10^4 solar masses per particle [Griffen et al. 2016]A Computational ChallengeDue to how computationally expensive such simulations are, previous N-body simulations of the growth of Milky-Way-like halos have consisted of only one or a few halos each. But in order to establish a statistical understanding of how galaxy halos form and find out whether the Milky Ways halo is typical or unusual! it is necessary to simulate a larger number of halos.In addition, in order to accurately follow the formation and evolution of substructure within the dark-matter halos, these simulations must be able to resolve the smallest dwarf galaxies, which are around a million solar masses. This requires an extremely high mass resolution, which adds to the computational expense of the simulation.First OutcomesThese are the challenges faced by

  10. Gravitationally Consistent Halo Catalogs and Merger Trees for Precision Cosmology

    Science.gov (United States)

    Behroozi, Peter S.; Wechsler, Risa H.; Wu, Hao-Yi; Busha, Michael T.; Klypin, Anatoly A.; Primack, Joel R.

    2013-01-01

    We present a new algorithm for generating merger trees and halo catalogs which explicitly ensures consistency of halo properties (mass, position, and velocity) across time steps. Our algorithm has demonstrated the ability to improve both the completeness (through detecting and inserting otherwise missing halos) and purity (through detecting and removing spurious objects) of both merger trees and halo catalogs. In addition, our method is able to robustly measure the self-consistency of halo finders; it is the first to directly measure the uncertainties in halo positions, halo velocities, and the halo mass function for a given halo finder based on consistency between snapshots in cosmological simulations. We use this algorithm to generate merger trees for two large simulations (Bolshoi and Consuelo) and evaluate two halo finders (ROCKSTAR and BDM). We find that both the ROCKSTAR and BDM halo finders track halos extremely well; in both, the number of halos which do not have physically consistent progenitors is at the 1%-2% level across all halo masses. Our code is publicly available at http://code.google.com/p/consistent-trees. Our trees and catalogs are publicly available at http://hipacc.ucsc.edu/Bolshoi/.

  11. Revealing the Cosmic Web-dependent Halo Bias

    Science.gov (United States)

    Yang, Xiaohu; Zhang, Youcai; Lu, Tianhuan; Wang, Huiyuan; Shi, Feng; Tweed, Dylan; Li, Shijie; Luo, Wentao; Lu, Yi; Yang, Lei

    2017-10-01

    Halo bias is the one of the key ingredients of the halo models. It was shown at a given redshift to be only dependent, to the first order, on the halo mass. In this study, four types of cosmic web environments—clusters, filaments, sheets, and voids—are defined within a state-of-the-art high-resolution N-body simulation. Within these environments, we use both halo-dark matter cross correlation and halo-halo autocorrelation functions to probe the clustering properties of halos. The nature of the halo bias differs strongly between the four different cosmic web environments described here. With respect to the overall population, halos in clusters have significantly lower biases in the {10}11.0˜ {10}13.5 {h}-1 {M}⊙ mass range. In other environments, however, halos show extremely enhanced biases up to a factor 10 in voids for halos of mass ˜ {10}12.0 {h}-1 {M}⊙ . Such a strong cosmic web environment dependence in the halo bias may play an important role in future cosmological and galaxy formation studies. Within this cosmic web framework, the age dependency of halo bias is found to be only significant in clusters and filaments for relatively small halos ≲ {10}12.5 {h}-1 {M}⊙ .

  12. High-speed machining of glass materials by laser-induced plasma-assisted ablation using a 532-nm laser

    Science.gov (United States)

    Zhang, J.; Sugioka, K.; Midorikawa, K.

    In this communication, we report a high-speed machining of glass materials by a novel laser ablation technique using a conventional visible laser for the first time. A high-quality micrograting structure is fabricated in fused quartz by laser-induced plasma-assisted ablation (LIPAA) using a second harmonic of Q-switched Nd+:YAG laser (532 nm). The plasma generated from a silver (Ag) target by the laser irradiation effectively assists in ablation of the fused quartz substrate by the same laser beam, although the laser beam is transparent to the substrate. A grating with a cross-sectional shape like a square-wave (period 20 μm) is achieved using the mask projection technique. The ablation rate reaches several tens nm/pulse. In addition, LIPAA is applied to high-speed hole drilling (700 μm in diameter) of fused-quartz (0.5 mm thick) and Pyrex glass (0.5 mm thick).

  13. Electric Properties of One-Neutron Halo Nuclei in Halo EFT

    Science.gov (United States)

    Braun, Jonas; Hammer, Hans-Werner

    2017-03-01

    We exploit the separation of scales in weakly-bound nuclei to compute E2 transitions and electric form factors in a halo effective field theory (EFT) framework. The relevant degrees of freedom are the core and the halo neutron. The EFT expansion is carried out in powers of R_{core}/R_{halo}, where R_{core} and R_{halo} denote the length scales of the core and halo, respectively. We include the strong s-wave and d-wave interactions by introducing dimer fields. The dimer propagators are regulated by employing the power divergence subtraction scheme and matched to the effective range expansion in the respective channel. Electromagnetic interactions are included via minimal substitution in the Lagrangian. We demonstrate that, depending on the observable and respective partial wave, additional local gauge-invariant operators contribute in LO, NLO and higher orders.

  14. Relating induced changes in EEG signals to orientation of visual stimuli using the ESI-256 machine.

    Science.gov (United States)

    Suarez, E; Viegas, M D; Adjouadi, M; Barreto, A

    2000-01-01

    The focus of this study is to investigate the relations that exist between changes in the orientation of simple visual stimuli displayed to a subject and the induced changes in brain activity recorded as EEG signals. These signals are recorded using the Electric Source Imaging with 256 electrodes (ESI-256). The 256-channel EEG signals of four subjects were measured monopolarly. Each subject was stimulated visually for approximately 7.5 minutes. The stimuli consisted of a series of 300 images depicting four basic orientations of a simple graphical element: a white bar on a black background, with each one of the four orientations (horizontal, vertical, +45 degrees and -45 degrees) shown a total of 75 times in a random order. The notion of missing information under certain orientations is not addressed at this juncture. The EEG signals produced by each subject were recorded in a continuous mode using a sampling rate of 1 kHz. Pre-processing of the raw EEG data obtained consisted of epoching, exclusion of faulty electrodes, and reduction of electro-oculogram (EOG) noise due to eye blinks. Topographical maps displaying brain activities and their individual electrode recordings are used as two different means for assessing these changes. It is important to note that the simplicity of the visual stimuli was considered in view of the massive data collected for interpretation. Our goal is to observe and determine new measures that would allow for the quantification and interpretation of such EEG brain activities. Such findings might prove useful for the later use of more complex stimuli and the potential development of size and orientation independent algorithms in image processing.

  15. Dependence of halo bias on mass and environment

    Science.gov (United States)

    Shi, Jingjing; Sheth, Ravi K.

    2018-01-01

    The simplest analyses of halo bias assume that halo mass alone determines halo clustering. However, if the large-scale environment is fixed, then halo clustering is almost entirely determined by environment, and is almost completely independent of halo mass. We show why. Our analysis is useful for studies that use the environmental dependence of clustering to constrain cosmological and galaxy formation models. It also shows why many correlations between galaxy properties and environment are merely consequences of the underlying correlations between haloes and their environments, and provides a framework for quantifying such inherited correlations.

  16. Conceptual design of hollow electron lenses for beam halo control in the Large Hadron Collider

    Energy Technology Data Exchange (ETDEWEB)

    Stancari, Giulio [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Previtali, Valentina [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Valishev, Alexander [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Bruce, Roderik [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Redaelli, Stefano [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Rossi, Adriana [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Salvachua Ferrando, Belen [European Organization for Nuclear Research (CERN), Geneva (Switzerland)

    2014-06-26

    Collimation with hollow electron beams is a technique for halo control in high-power hadron beams. It is based on an electron beam (possibly pulsed or modulated in intensity) guided by strong axial magnetic fields which overlaps with the circulating beam in a short section of the ring. The concept was tested experimentally at the Fermilab Tevatron collider using a hollow electron gun installed in one of the Tevatron electron lenses. We are proposing a conceptual design for applying this technique to the Large Hadron Collider at CERN. A prototype hollow electron gun for the LHC was built and tested. The expected performance of the hollow electron beam collimator was based on Tevatron experiments and on numerical tracking simulations. Halo removal rates and enhancements of halo diffusivity were estimated as a function of beam and lattice parameters. Proton beam core lifetimes and emittance growth rates were checked to ensure that undesired effects were suppressed. Hardware specifications were based on the Tevatron devices and on preliminary engineering integration studies in the LHC machine. Required resources and a possible timeline were also outlined, together with a brief discussion of alternative halo-removal schemes and of other possible uses of electron lenses to improve the performance of the LHC.

  17. Angular momentum properties of haloes and their baryon content in the Illustris simulation

    Science.gov (United States)

    Zjupa, Jolanta; Springel, Volker

    2017-04-01

    The angular momentum properties of virialized dark matter haloes have been measured with good statistics in collisionless N-body simulations, but an equally accurate analysis of the baryonic spin is still missing. We employ the Illustris simulation suite, one of the first simulations of galaxy formation with full hydrodynamics that produces a realistic galaxy population in a sizeable volume, to quantify the baryonic spin properties for more than ˜320 000 haloes. We first compare the systematic differences between different spin parameter and halo definitions, and the impact of sample selection criteria on the derived properties. We confirm that dark-matter-only haloes exhibit a close to self-similar spin distribution in mass and redshift of lognormal form. However, the physics of galaxy formation radically changes the baryonic spin distribution. While the dark matter component remains largely unaffected, strong trends with mass and redshift appear for the spin of diffuse gas and the formed stellar component. With time, the baryons staying bound to the halo develop a misalignment of their spin vector with respect to dark matter, and increase their specific angular momentum by a factor of ˜1.3 in the non-radiative case and ˜1.8 in the full physics setup at z = 0. We show that this enhancement in baryonic spin can be explained by the combined effect of specific angular momentum transfer from dark matter on to gas during mergers and from feedback expelling low specific angular momentum gas from the halo. Our results challenge certain models for spin evolution and underline the significant changes induced by baryonic physics in the structure of haloes.

  18. Characterization of residual stresses in heat treated Ti-6Al-4V forgings by machining induced distortion

    Directory of Open Access Journals (Sweden)

    Werner E.

    2010-06-01

    Full Text Available To provide a solid base for improved material exploitation in dimensioning calculations it is necessary to determine the stress state in the part prior to service loading. In order to achieve higher material strength at elevated temperatures, the surface temperature gradient with respect to time has to be sufficiently high during heat treatment. This results in non-negligable residual stresses that can reduce the allowable load level upon which yielding occurs. For titanium alloys there are two common heat treatments, namely solution treatment and mill annealing. The latter one is the method of choice within the presented project. Mill annealing is utilized in order to significantly reduce the residual stresses in the parts without loosing much of the improved strength at elevated temperatures. Quantification of residual stresses is done by solving an inverse problem. From the measurement of distortion, induced by dividing the investigated part, the residual stress state can be calculated via analytical modeling or correlation with finite element models. To assure a minimum perturbation of the residual stress state during specimen production, dividing of the part is accomplished by electric discharge machining. The parts of interest are v-shaped prisms with a length of approximatly 450 mm and a thickness in the cross sectional area from about 20 mm to 45 mm. Figure 1(a shows the forged part and 1(b the dimensions of the cross section in millimeters as well as the material properties considered in the finite element model. The heat exchange between the part and the environment is modelled as heat transfer by convection superimposed with heat radiation. Since the parts are exposed to air during forging and heat treatment, the surface develops a strongly adhesive oxide layer, the so called alpha-case. After forging the parts are cooled in air and heat treated at a temperature of 720° C for a duration of 120 min. Subsequent air cooling and

  19. Characterization of residual stresses in heat treated Ti-6Al-4V forgings by machining induced distortion

    Science.gov (United States)

    Regener, B.; Krempaszky, C.; Werner, E.

    2010-06-01

    To provide a solid base for improved material exploitation in dimensioning calculations it is necessary to determine the stress state in the part prior to service loading. In order to achieve higher material strength at elevated temperatures, the surface temperature gradient with respect to time has to be sufficiently high during heat treatment. This results in non-negligable residual stresses that can reduce the allowable load level upon which yielding occurs. For titanium alloys there are two common heat treatments, namely solution treatment and mill annealing. The latter one is the method of choice within the presented project. Mill annealing is utilized in order to significantly reduce the residual stresses in the parts without loosing much of the improved strength at elevated temperatures. Quantification of residual stresses is done by solving an inverse problem. From the measurement of distortion, induced by dividing the investigated part, the residual stress state can be calculated via analytical modeling or correlation with finite element models. To assure a minimum perturbation of the residual stress state during specimen production, dividing of the part is accomplished by electric discharge machining. The parts of interest are v-shaped prisms with a length of approximatly 450 mm and a thickness in the cross sectional area from about 20 mm to 45 mm. Figure 1(a) shows the forged part and 1(b) the dimensions of the cross section in millimeters as well as the material properties considered in the finite element model. The heat exchange between the part and the environment is modelled as heat transfer by convection superimposed with heat radiation. Since the parts are exposed to air during forging and heat treatment, the surface develops a strongly adhesive oxide layer, the so called alpha-case. After forging the parts are cooled in air and heat treated at a temperature of 720° C for a duration of 120 min. Subsequent air cooling and removing the alpha-case by

  20. Stability of BEC galactic dark matter halos

    Energy Technology Data Exchange (ETDEWEB)

    Guzmán, F.S.; Lora-Clavijo, F.D.; González-Avilés, J.J.; Rivera-Paleo, F.J., E-mail: guzman@ifm.umich.mx, E-mail: fadulora@ifm.umich.mx, E-mail: javiles@ifm.umich.mx, E-mail: friverap@ifm.umich.mx [Instituto de Física y Matemáticas, Universidad Michoacana de San Nicolás de Hidalgo, Edificio C-3, Cd. Universitaria, 58040 Morelia, Michoacán (Mexico)

    2013-09-01

    In this paper we show that spherically symmetric BEC dark matter halos, with the sin r/r density profile, that accurately fit galactic rotation curves and represent a potential solution to the cusp-core problem are unstable. We do this by introducing back the density profiles into the fully time-dependent Gross-Pitaevskii-Poisson system of equations. Using numerical methods to track the evolution of the system, we found that these galactic halos lose mass at an approximate rate of half of its mass in a time scale of dozens of Myr. We consider this time scale is enough as to consider these halos are unstable and unlikely to be formed. We provide some arguments to show that this behavior is general and discuss some other drawbacks of the model that restrict its viability.

  1. The dark halo of the Milky Way.

    Science.gov (United States)

    Alcock, C.

    2000-01-01

    Most of the matter in the Milky Way is invisible to astronomers. Precise numbers are elusive, but it appears that the dark component is 20 times as massive as the visible disk of stars and gas. This dark matter is distributed in space differently than the stars, forming a vast, diffuse halo, more spherical than disklike, which occupies more than 1000 times the volume of the disk of stars. The composition of this dark halo is unknown, but it may comprise a mixture of ancient, degenerate dwarf stars and exotic, hypothetical elementary particles.

  2. Complex artificial halos for the classroom

    Science.gov (United States)

    Selmke, Markus; Selmke, Sarah

    2016-07-01

    Halos represent a common and imposing atmospheric optics phenomenon whose displays are caused by tiny air-borne ice crystals. Their variety stems from a certain set of orientation classes to which these crystals belong. We present a robust and inexpensive device, made of modular components, that allows for the replication of most of these orientation classes in the laboratory. Under the illumination of light, the corresponding artificial halo counterparts emerge. The mechanical realization of this device allows a thorough understanding and demonstration of these beautiful atmospheric optics phenomena.

  3. Dark energy and extended dark matter halos

    Science.gov (United States)

    Chernin, A. D.; Teerikorpi, P.; Valtonen, M. J.; Dolgachev, V. P.; Domozhilova, L. M.; Byrd, G. G.

    2012-03-01

    The cosmological mean matter (dark and baryonic) density measured in the units of the critical density is Ωm = 0.27. Independently, the local mean density is estimated to be Ωloc = 0.08-0.23 from recent data on galaxy groups at redshifts up to z = 0.01-0.03 (as published by Crook et al. 2007, ApJ, 655, 790 and Makarov & Karachentsev 2011, MNRAS, 412, 2498). If the lower values of Ωloc are reliable, as Makarov & Karachentsev and some other observers prefer, does this mean that the Local Universe of 100-300 Mpc across is an underdensity in the cosmic matter distribution? Or could it nevertheless be representative of the mean cosmic density or even be an overdensity due to the Local Supercluster therein. We focus on dark matter halos of groups of galaxies and check how much dark mass the invisible outer layers of the halos are able to host. The outer layers are usually devoid of bright galaxies and cannot be seen at large distances. The key factor which bounds the size of an isolated halo is the local antigravity produced by the omnipresent background of dark energy. A gravitationally bound halo does not extend beyond the zero-gravity surface where the gravity of matter and the antigravity of dark energy balance, thus defining a natural upper size of a system. We use our theory of local dynamical effects of dark energy to estimate the maximal sizes and masses of the extended dark halos. Using data from three recent catalogs of galaxy groups, we show that the calculated mass bounds conform with the assumption that a significant amount of dark matter is located in the invisible outer parts of the extended halos, sufficient to fill the gap between the observed and expected local matter density. Nearby groups of galaxies and the Virgo cluster have dark halos which seem to extend up to their zero-gravity surfaces. If the extended halo is a common feature of gravitationally bound systems on scales of galaxy groups and clusters, the Local Universe could be typical or even

  4. Triple Halo Coil: Development and Comparison with Other TMS Coils

    Science.gov (United States)

    Rastogi, Priyam; Hadimani, Ravi; Jiles, David

    Transcranial Magnetic Stimulation (TMS) is a non-invasive stimulation technique that can be used for the treatment of various neurological disorders such as Parkinson's Disease, PTSD, TBI and anxiety by regulating synaptic activity. TMS is FDA approved for the treatment of major depressive disorder. There is a critical need to develop deep TMS coils that can stimulate deeper regions of the brain without excessively stimulating the cortex in order to provide an alternative to surgical methods. We have developed a novel multi-coil configuration called ``Triple Halo Coil'' (THC) that can stimulate deep brain regions. Investigation of induced electric and magnetic field in these regions have been achieved by computer modelling. Comparison of the results due to THC configuration have been conducted with other TMS coils such as ``Halo Coil'', circular coil and ``Figure of Eight'' coil. There was an improvement of more than 15 times in the strength of magnetic field, induced by THC configuration at 10 cm below the vertex of the head when compared with the ``Figure of Eight'' coil alone. Carver Charitable Trust.

  5. Estimation of the aging grade of T91 steel by laser-induced breakdown spectroscopy coupled with support vector machines

    Science.gov (United States)

    Lu, Shengzi; Dong, Meirong; Huang, Jianwei; Li, Wenbing; Lu, Jidong; Li, Jun

    2018-02-01

    T91 steel is a representative martensitic heat-resistant steel widely used in high temperature compression components of industrial equipment. During the service period, the operation safety and the service life of the equipment will be affected by the change of structure and mechanical properties of the steel components, which is called material aging. In order to develop a rapid in-situ aging estimation technology of high temperature compression components surface, laser-induced breakdown spectroscopy (LIBS) coupled with support vector machine (SVM) was employed in this paper. The spectral characteristics of 10 T91 steel specimens with different aging grades were analyzed. Line intensities and the line intensity ratios (ionic/atomic and alloying element/matrix element) that indicate the change of metallographic structure were used to establish SVM models, and the results using different variable sets were compared. The model was optimized by comparing different pulse number for practical effectiveness, and the robustness of the model was investigated in dealing with the inhomogeneity of steel composition. The study results show that the estimation model obtained the best performance using line intensities and line intensity ratios averaged from 31st-60th laser pulses as input variables. The estimation accuracy of validation set was greatly improved from 75.8% to 95.3%. In addition, the model showed the outstanding capacity for handling the fluctuations of spectral signals between measuring-points (spots), which indicated that the aging estimation based on a few measuring-points is feasible. The studies presented here demonstrate that the LIBS coupled with SVM is a new useful technique for the aging estimation of steel, and would be well-suited for fast safety assessment in industrial field.

  6. One-proton halo in 26P and two-proton halo in 27S

    Science.gov (United States)

    Ren, Zhongzhou; Chen, Baoqiu; Ma, Zhongyu; Xu, Gongou

    1996-02-01

    Proton-drip-line nuclei 26P and 27S are studied in the nonlinear relativistic mean-field theory. Calculations show that the mean-square radius of protons in the 2s1/2 state is approximately 18-20 fm2 which is abnormally large as compared with the mean-square radii of proton, neutron, and matter distributions, giving a strong evidence for proton halos in 26P and 27S. This indicates that the size of proton halos is as large as that of neutron halos although there exists the Coulomb barrier in proton-drip-line nuclei.

  7. Machine Translation

    Institute of Scientific and Technical Information of China (English)

    张严心

    2015-01-01

    As a kind of ancillary translation tool, Machine Translation has been paid increasing attention to and received different kinds of study by a great deal of researchers and scholars for a long time. To know the definition of Machine Translation and to analyse its benefits and problems are significant for translators in order to make good use of Machine Translation, and helpful to develop and consummate Machine Translation Systems in the future.

  8. Sustainable machining

    CERN Document Server

    2017-01-01

    This book provides an overview on current sustainable machining. Its chapters cover the concept in economic, social and environmental dimensions. It provides the reader with proper ways to handle several pollutants produced during the machining process. The book is useful on both undergraduate and postgraduate levels and it is of interest to all those working with manufacturing and machining technology.

  9. Substructure in the Stellar Halos of the Aquarius Simulations

    NARCIS (Netherlands)

    Helmi, Amina; Cooper, A. P.; White, S. D. M.; Cole, S.; Frenk, C. S.; Navarro, J. F.

    2011-01-01

    We characterize the substructure in the simulated stellar halos of Cooper et al. which were formed by the disruption of satellite galaxies within the cosmological N-body simulations of galactic halos of the Aquarius project. These stellar halos exhibit a wealth of tidal features: broad overdensities

  10. Halo white dwarfs in the Gaia era

    NARCIS (Netherlands)

    van Oirschot, P.; Nelemans, G.; Pols, O.; Helmi, A.; Tolstoy, E.; Brown, A. G. A.; Pugliese, G.; de Koter, A.; Wijburg, M.

    The Galactic Halo is the oldest and most metal-poor component of the Galaxy. It is studied in detail both to understand the formation and evolution of galaxies, as well as the formation and evolution of the earliest stars. With this aim in mind, we plan to couple a population synthesis model to a

  11. New (theoretical) Perspectives on the Galactic Halo

    NARCIS (Netherlands)

    Helmi, A.; Turon, C; Meynadier, F; Arenou, F

    1 discuss recent progress in our understanding of the formation of the stellar halo of the Milky Way in the context of the concordance cosmological model. The Gaia mission will provide unique insights especially into the early assembly of the Galaxy and likely be key in unraveling its merger

  12. Reflection halo twins : subsun and supersun

    NARCIS (Netherlands)

    Konnen, Gunther P.; van der Werf, Siebren Y.

    2011-01-01

    From an aircraft, a short distinct vertical structure is sometimes seen above the setting sun. Such a feature can be understood as a halo, which is the counterpart of the well-known subsun. Whereas the latter arises from reflections off basal faces of plate-oriented ice crystals illuminated from

  13. Streams in the Aquarius stellar haloes

    NARCIS (Netherlands)

    Gomez, Facundo A.; Helmi, Amina; Cooper, Andrew P.; Frenk, Carlos S.; Navarro, Julio F.; White, Simon D. M.

    2013-01-01

    We use the very high resolution, fully cosmological simulations from the Aquarius Project, coupled to a semi-analytical model of galaxy formation, to study the phase-space distribution of halo stars in 'solar neighbourhood' like volumes. We find that this distribution is very rich in substructure in

  14. Beam halo in high-intensity hadron linacs

    Energy Technology Data Exchange (ETDEWEB)

    Gerigk, F.

    2006-12-21

    This document aims to cover the most relevant mechanisms for the development of beam halo in high-intensity hadron linacs. The introduction outlines the various applications of high-intensity linacs and it will explain why, in the case of the CERN Superconducting Proton Linac (SPL) study a linac was chosen to provide a high-power beam, rather than a different kind of accelerator. The basic equations, needed for the understanding of halo development are derived and employed to study the effects of initial and distributed mismatch on high-current beams. The basic concepts of the particle-core model, envelope modes, parametric resonances, the free-energy approach, and the idea of core-core resonances are introduced and extended to study beams in realistic linac lattices. The approach taken is to study the behavior of beams not only in simplified theoretical focusing structures but to highlight the beam dynamics in realistic accelerators. All effects which are described and derived with simplified analytic models, are tested in realistic lattices and are thus related to observable effects in linear accelerators. This approach involves the use of high-performance particle tracking codes, which are needed to simulate the behavior of the outermost particles in distributions of up to 100 million macro particles. In the end a set of design rules are established and their impact on the design of a typical high-intensity machine, the CERN SPL, is shown. The examples given in this document refer to two different design evolutions of the SPL study: the first conceptual design report (SPL I) and the second conceptual design report (SPL II). (orig.)

  15. The Impact of Theoretical Uncertainties in the Halo Mass Function and Halo

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Hao-Yi; Zentner, Andrew R.; Wechsler, Risa H.; /KIPAC, Menlo Park /SLAC /Pittsburgh U. /KIPAC, Menlo Park /SLAC

    2010-06-04

    We study the impact of theoretical uncertainty in the dark matter halo mass function and halo bias on dark energy constraints from imminent galaxy cluster surveys. We find that for an optical cluster survey like the Dark Energy Survey, the accuracy required on the predicted halo mass function to make it an insignificant source of error on dark energy parameters is {approx}1%. The analogous requirement on the predicted halo bias is less stringent ({approx}5%), particularly if the observable-mass distribution can be well constrained by other means. These requirements depend upon survey area but are relatively insensitive to survey depth. The most stringent requirements are likely to come from a survey over a significant fraction of the sky that aims to observe clusters down to relatively low mass, M{sub th}{approx} 10{sup 13.7} h{sup -1} M{sub sun}; for such a survey, the mass function and halo bias must be predicted to accuracies of {approx}0.5% and {approx}1%, respectively. These accuracies represent a limit on the practical need to calibrate ever more accurate halo mass and bias functions. We find that improving predictions for the mass function in the low-redshift and low-mass regimes is the most effective way to improve dark energy constraints.

  16. Parametrizing the stellar haloes of galaxies

    Science.gov (United States)

    D'Souza, Richard; Kauffman, Guinevere; Wang, Jing; Vegetti, Simona

    2014-09-01

    We study the stellar haloes of galaxies out to 70-100 kpc as a function of stellar mass and galaxy type by stacking aligned r- and g-band images from a sample of 45 508 galaxies from Sloan Digital Sky Survey Data Release 9 in the redshift range 0.06 ≤ z ≤ 0.1 and in the mass range 1010.0 M⊙ < M* < 1011.4 M⊙. We derive surface brightness profiles to a depth of almost μr ˜ 32 mag arcsec-2. We find that the ellipticity of the stellar halo is a function of galaxy stellar mass and that the haloes of high-concentration galaxies are more elliptical than those of low-concentration galaxies. Where the g - r colour of the stellar halo can be measured, we find that the stellar light is always bluer than in the main galaxy. The colour of the stellar halo is redder for more massive galaxies. We further demonstrate that the full two-dimensional surface intensity distribution of our galaxy stacks can only be fit through multicomponent Sérsic models. Using the fraction of light in the outer component of the models as a proxy for the fraction of accreted stellar light, we show that this fraction is a function of stellar mass and galaxy type. The fraction of accreted stellar light rises from 30 to 70 per cent and from 2 to 25 per cent for high- and low-concentration galaxies, respectively, over the mass range 1010.0-1011.4 M⊙.

  17. Supervised Machine Learning for Classification of the Electrophysiological Effects of Chronotropic Drugs on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

    Directory of Open Access Journals (Sweden)

    Christopher Heylman

    Full Text Available Supervised machine learning can be used to predict which drugs human cardiomyocytes have been exposed to. Using electrophysiological data collected from human cardiomyocytes with known exposure to different drugs, a supervised machine learning algorithm can be trained to recognize and classify cells that have been exposed to an unknown drug. Furthermore, the learning algorithm provides information on the relative contribution of each data parameter to the overall classification. Probabilities and confidence in the accuracy of each classification may also be determined by the algorithm. In this study, the electrophysiological effects of β-adrenergic drugs, propranolol and isoproterenol, on cardiomyocytes derived from human induced pluripotent stem cells (hiPS-CM were assessed. The electrophysiological data were collected using high temporal resolution 2-photon microscopy of voltage sensitive dyes as a reporter of membrane voltage. The results demonstrate the ability of our algorithm to accurately assess, classify, and predict hiPS-CM membrane depolarization following exposure to chronotropic drugs.

  18. Supervised Machine Learning for Classification of the Electrophysiological Effects of Chronotropic Drugs on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

    Science.gov (United States)

    Heylman, Christopher; Datta, Rupsa; Sobrino, Agua; George, Steven; Gratton, Enrico

    2015-01-01

    Supervised machine learning can be used to predict which drugs human cardiomyocytes have been exposed to. Using electrophysiological data collected from human cardiomyocytes with known exposure to different drugs, a supervised machine learning algorithm can be trained to recognize and classify cells that have been exposed to an unknown drug. Furthermore, the learning algorithm provides information on the relative contribution of each data parameter to the overall classification. Probabilities and confidence in the accuracy of each classification may also be determined by the algorithm. In this study, the electrophysiological effects of β-adrenergic drugs, propranolol and isoproterenol, on cardiomyocytes derived from human induced pluripotent stem cells (hiPS-CM) were assessed. The electrophysiological data were collected using high temporal resolution 2-photon microscopy of voltage sensitive dyes as a reporter of membrane voltage. The results demonstrate the ability of our algorithm to accurately assess, classify, and predict hiPS-CM membrane depolarization following exposure to chronotropic drugs.

  19. Dynamics of the Disruption Halo Current Toroidal Asymmetry in NSTX

    Energy Technology Data Exchange (ETDEWEB)

    S.P. Gerhardt

    2012-09-27

    This paper describes the dynamics of disruption halo current non-axisymmetries in the lower divertor of the National Spherical Torus Experiment [M. Ono, et al. Nuclear Fusion 40, 557 (2000)]. While. The halo currents typically have a strongly asymmetric structure where they enter the divertor floor, and this asymmetry has been observed to complete up to 7 toroidal revolutions over the duration of the halo current pulse. However, the rotation speed and toroidal extend of the asymmetry can vary significantly during the pulse. The rotation speed, halo current pulse duration, and total number of revolutions tend to be smaller in cases with large halo currents. The halo current pattern is observed to become toroidally symmetric at the end of the halo current pulse. It is proposed that this symmeterization is due to the loss of most or all of the closed field line geometry in the final phase of the vertical displacement event.

  20. ORIGAMI: DELINEATING HALOS USING PHASE-SPACE FOLDS

    Energy Technology Data Exchange (ETDEWEB)

    Falck, Bridget L.; Neyrinck, Mark C.; Szalay, Alexander S. [Department of Physics and Astronomy, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218 (United States)

    2012-08-01

    We present the ORIGAMI method of identifying structures, particularly halos, in cosmological N-body simulations. Structure formation can be thought of as the folding of an initially flat three-dimensional manifold in six-dimensional phase space. ORIGAMI finds the outer folds that delineate these structures. Halo particles are identified as those that have undergone shell-crossing along three orthogonal axes, providing a dynamical definition of halo regions that is independent of density. ORIGAMI also identifies other morphological structures: particles that have undergone shell-crossing along 2, 1, or 0 orthogonal axes correspond to filaments, walls, and voids, respectively. We compare this method to a standard friends-of-friends halo-finding algorithm and find that ORIGAMI halos are somewhat larger, more diffuse, and less spherical, though the global properties of ORIGAMI halos are in good agreement with other modern halo-finding algorithms.

  1. Using Tidal Tails to Probe Dark Matter Halos

    Science.gov (United States)

    Mihos, Chris; Dubinski, John; Hernquist, Lars

    1995-03-01

    We present a series of numerical simulations of merging galaxies to explore the effect of differing halo mass distributions on the morphology of tidal tails. We employ composite disk/bulge/halo galaxy models which span a range of halo properties from low mass, compact halos to very massive, extended halos, and possess identically flat rotation curves inside a few disk scale lengths. These merger experiments are performed with a range of impact parameters, inclinations and mass ratios for the galaxies as well. Our simulations indicate that even under the most favorable conditions, galaxies with extended dark matter halos produce very anemic tidal tails when merging. In light of several observed mergers which sport prominent tidal tails --- e.g., NGC 7252, NGC 4038/39 (``The Antennae"), NGC 4676, and most spectacularly IRAS 19254-7245 (``The Superantennae") --- our results suggest that galaxy halos may be significantly more compact and less massive than expected in Omega =1 cosmological scenarios.

  2. A HaloTag-based multi-color fluorogenic sensor visualizes and quantifies proteome stress in live cells using solvatochromic and molecular rotor-based fluorophores.

    Science.gov (United States)

    Liu, Yu; Miao, Kun; Li, Yinghao; Fares, Matthew; Chen, Shuyuan; Zhang, Xin

    2018-02-23

    Protein homeostasis, or proteostasis, is essential for cellular fitness and viability. Many environmental factors compromise proteostasis, induce global proteome stress, and cause diseases. Proteome stress sensor is a powerful tool to dissect the mechanism of cellular stress and find therapeutics that ameliorate these diseases. In this work, we present a multi-color HaloTag-based sensor (named AgHalo) to visualize and quantify proteome stresses in live cells. The current AgHalo sensor is equipped with three fluorogenic probes that turn on fluorescence when the sensor forms either soluble oligomers or insoluble aggregates upon exposure to stress conditions, both in vitro and in cellulo. Further, AgHalo probes can be combined with commercially available always-fluorescent HaloTag ligands to enable two-color imaging, allowing for direct visualization of the AgHalo sensor both before and after subjecting cells to stress conditions. Finally, pulse-chase experiments can be carried out to discern changes in cellular proteome in live cells by first forming the AgHalo conjugate and then either applying or removing stress at any desired time point. In summary, the AgHalo sensor can be used to visualize and quantify proteome stress in live cells, a task that is difficult to accomplish using previous always-fluorescent methods. This sensor should be suited to evaluate cellular proteostasis under various exogenous stresses, including chemical toxins, drugs, and environmental factors.

  3. A DISTANT RADIO MINI-HALO IN THE PHOENIX GALAXY CLUSTER

    Energy Technology Data Exchange (ETDEWEB)

    Van Weeren, R. J.; Andrade-Santos, F.; Forman, W. R.; Jones, C. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Intema, H. T. [National Radio Astronomy Observatory, 1003 Lopezville Road, Socorro, NM 87801-0387 (United States); Lal, D. V. [National Centre for Radio Astrophysics, TIFR, Pune University Campus, Post Bag 3, Pune 411 007 (India); Brüggen, M.; De Gasperin, F. [Hamburger Sternwarte, Gojenbergsweg 112, D-21029 Hamburg (Germany); Hoeft, M. [Thüringer Landessternwarte Tautenburg, Sternwarte 5, D-07778, Tautenburg (Germany); Nuza, S. E. [Leibniz-Institut für Astrophysik Potsdam (AIP), An der Sternwarte 16, D-14482 Potsdam (Germany); Röttgering, H. J. A.; Stroe, A., E-mail: rvanweeren@cfa.harvard.edu [Leiden Observatory, Leiden University, P.O. Box 9513, NL-2300 RA Leiden (Netherlands)

    2014-05-10

    We report the discovery of extended radio emission in the Phoenix cluster (SPT-CL J2344-4243, z = 0.596) with the Giant Metrewave Radio Telescope (GMRT) at 610 MHz. The diffuse emission extends over a region of at least 400-500 kpc and surrounds the central radio source of the Brightest Cluster Galaxy, but does not appear to be directly associated with it. We classify the diffuse emission as a radio mini-halo, making it the currently most distant mini-halo known. Radio mini-halos have been explained by synchrotron emitting particles re-accelerated via turbulence, possibly induced by gas sloshing generated from a minor merger event. Chandra observations show a non-concentric X-ray surface brightness distribution, which is consistent with this sloshing interpretation. The mini-halo has a flux density of 17 ± 5 mJy, resulting in a 1.4 GHz radio power of (10.4 ± 3.5) × 10{sup 24} W Hz{sup –1}. The combined cluster emission, which includes the central compact radio source, is also detected in a shallow GMRT 156 MHz observation and together with the 610 MHz data we compute a spectral index of –0.84 ± 0.12 for the overall cluster radio emission. Given that mini-halos typically have steeper radio spectra than cluster radio galaxies, this spectral index should be taken as an upper limit for the mini-halo.

  4. Precise halo orbit design and optimal transfer to halo orbits from earth using differential evolution

    Science.gov (United States)

    Nath, Pranav; Ramanan, R. V.

    2016-01-01

    The mission design to a halo orbit around the libration points from Earth involves two important steps. In the first step, we design a halo orbit for a specified size and in the second step, we obtain an optimal transfer trajectory design to the halo orbit from an Earth parking orbit. Conventionally, the preliminary design for these steps is obtained using higher order analytical solution and the dynamical systems theory respectively. Refinements of the design are carried out using gradient based methods such as differential correction and pseudo arc length continuation method under the of circular restricted three body model. In this paper, alternative single level schemes are developed for both of these steps based on differential evolution, an evolutionary optimization technique. The differential evolution based scheme for halo orbit design produces precise halo orbit design avoiding the refinement steps. Further, in this approach, prior knowledge of higher order analytical solutions for the halo orbit design is not needed. The differential evolution based scheme for the transfer trajectory, identifies the precise location on the halo orbit that needs minimum energy for insertion and avoids exploration of multiple points. The need of a close guess is removed because the present scheme operates on a set of bounds for the unknowns. The constraint on the closest approach altitude from Earth is handled through objective function. The use of these schemes as the design and analysis tools within the of circular restricted three body model is demonstrated through case studies for missions to the first libration point of Sun-Earth system.

  5. Simple machines

    CERN Document Server

    Graybill, George

    2007-01-01

    Just how simple are simple machines? With our ready-to-use resource, they are simple to teach and easy to learn! Chocked full of information and activities, we begin with a look at force, motion and work, and examples of simple machines in daily life are given. With this background, we move on to different kinds of simple machines including: Levers, Inclined Planes, Wedges, Screws, Pulleys, and Wheels and Axles. An exploration of some compound machines follows, such as the can opener. Our resource is a real time-saver as all the reading passages, student activities are provided. Presented in s

  6. The Halo B2B Studio

    Science.gov (United States)

    Gorzynski, Mark; Derocher, Mike; Mitchell, April Slayden

    Research underway at Hewlett-Packard on remote communication resulted in the identification of three important components typically missing in existing systems. These missing components are: group nonverbal communication capabilities, high-resolution interactive data capabilities, and global services. Here we discuss some of the design elements in these three areas as part of the Halo program at HP, a remote communication system shown to be effective to end-users.

  7. Beam Shape and Halo Monitor Study

    CERN Document Server

    Lallement, J B; Hori, M; CERN. Geneva. AB Department

    2006-01-01

    The Beam Shape and Halo Monitor, designed by Masaki Hori, is the main diagnostic tool for the 3 MeV test stand scheduled in 2008. This detector will be able to measure the transverse halo generated in the RFQ and the Chopper-line and to detect and measure the longitudinal halo composed of the incompletely chopped bunches. Its principle of functioning is the following: H- ions hit a carbon foil and generate secondary electrons with the same spatial distribution than the incoming beam and a current depending on an emission coefficient given by the carbon foil. These electrons are accelerated towards a phosphor screen by an electric field applied between accelerating grids. Once the electrons reach the phosphor screen, they generate light which is transmitted to a CCD camera via optic fibers [1]. It is expected to give a time resolution of 1-2ns and a spatial resolution of 1mm. The first test of the BSHM done with a Laser has shown a spatial resolution bigger than 1cm and the time resolution bigger than 2ns[2]. ...

  8. Dissecting Halo Components in IFU Data

    Directory of Open Access Journals (Sweden)

    Michael Merrifield

    2017-05-01

    Full Text Available While most astronomers are now familiar with tools to decompose images into multiple components such as disks, bulges, and halos, the equivalent techniques for spectral data cubes are still in their infancy. This is unfortunate, as integral field unit (IFU spectral surveys are now producing a mass of data in this format, which we are ill-prepared to analyze effectively. We have therefore been developing new tools to separate out components using this full spectral data. The results of such analyses will prove invaluable in determining not only whether such decompositions have an astrophysical significance, but, where they do, also in determining the relationship between the various elements of a galaxy. Application to a pilot study of IFU data from the cD galaxy NGC 3311 confirms that the technique can separate the stellar halo from the underlying galaxy in such systems, and indicates that, in this case, the halo is older and more metal poor than the galaxy, consistent with it forming from the cannibalism of smaller satellite galaxies. The success of the method bodes well for its application to studying the larger samples of cD galaxies that IFU surveys are currently producing.

  9. The Extended Baryonic Halo of NGC 3923

    Directory of Open Access Journals (Sweden)

    Bryan W. Miller

    2017-07-01

    Full Text Available Galaxy halos and their globular cluster systems build up over time by the accretion of small satellites. We can learn about this process in detail by observing systems with ongoing accretion events and comparing the data with simulations. Elliptical shell galaxies are systems that are thought to be due to ongoing or recent minor mergers. We present preliminary results of an investigation of the baryonic halo—light profile, globular clusters, and shells/streams—of the shell galaxy NGC 3923 from deep Dark Energy Camera (DECam g and i-band imaging. We present the 2D and radial distributions of the globular cluster candidates out to a projected radius of about 185 kpc, or ∼ 37 R e , making this one of the most extended cluster systems studied. The total number of clusters implies a halo mass of M h ∼ 3 × 10 13 M ⊙ . Previous studies had identified between 22 and 42 shells, making NGC 3923 the system with the largest number of shells. We identify 23 strong shells and 11 that are uncertain. Future work will measure the halo mass and mass profile from the radial distributions of the shell, N-body models, and line-of-sight velocity distribution (LOSVD measurements of the shells using the Multi Unit Spectroscopic Explorer (MUSE.

  10. Electric machine

    Science.gov (United States)

    El-Refaie, Ayman Mohamed Fawzi [Niskayuna, NY; Reddy, Patel Bhageerath [Madison, WI

    2012-07-17

    An interior permanent magnet electric machine is disclosed. The interior permanent magnet electric machine comprises a rotor comprising a plurality of radially placed magnets each having a proximal end and a distal end, wherein each magnet comprises a plurality of magnetic segments and at least one magnetic segment towards the distal end comprises a high resistivity magnetic material.

  11. Permutation Machines.

    Science.gov (United States)

    Bhatia, Swapnil; LaBoda, Craig; Yanez, Vanessa; Haddock-Angelli, Traci; Densmore, Douglas

    2016-08-19

    We define a new inversion-based machine called a permuton of n genetic elements, which allows the n elements to be rearranged in any of the n·(n - 1)·(n - 2)···2 = n! distinct orderings. We present two design algorithms for architecting such a machine. We define a notion of a feasible design and use the framework to discuss the feasibility of the permuton architectures. We have implemented our design algorithms in a freely usable web-accessible software for exploration of these machines. Permutation machines could be used as memory elements or state machines and explicitly illustrate a rational approach to designing biological systems.

  12. Recoiling supermassive black hole escape velocities from dark matter haloes

    Science.gov (United States)

    Choksi, Nick; Behroozi, Peter; Volonteri, Marta; Schneider, Raffaella; Ma, Chung-Pei; Silk, Joseph; Moster, Benjamin

    2017-12-01

    We simulate recoiling black hole trajectories from z = 20 to z = 0 in dark matter haloes, quantifying how parameter choices affect escape velocities. These choices include the strength of dynamical friction, the presence of stars and gas, the accelerating expansion of the Universe (Hubble acceleration), host halo accretion and motion, and seed black hole mass. Lambda cold dark matter halo accretion increases escape velocities by up to 0.6 dex and significantly shortens return time-scales compared to non-accreting cases. Other parameters change orbit damping rates but have subdominant effects on escape velocities; dynamical friction is weak at halo escape velocities, even for extreme parameter values. We present formulae for black hole escape velocities as a function of host halo mass and redshift. Finally, we discuss how these findings affect black hole mass assembly as well as minimum stellar and halo masses necessary to retain supermassive black holes.

  13. The “Building Blocks” of Stellar Halos

    Directory of Open Access Journals (Sweden)

    Kyle A. Oman

    2017-08-01

    Full Text Available The stellar halos of galaxies encode their accretion histories. In particular, the median metallicity of a halo is determined primarily by the mass of the most massive accreted object. We use hydrodynamical cosmological simulations from the apostle project to study the connection between the stellar mass, the metallicity distribution, and the stellar age distribution of a halo and the identity of its most massive progenitor. We find that the stellar populations in an accreted halo typically resemble the old stellar populations in a present-day dwarf galaxy with a stellar mass ∼0.2–0.5 dex greater than that of the stellar halo. This suggests that had they not been accreted, the primary progenitors of stellar halos would have evolved to resemble typical nearby dwarf irregulars.

  14. The Machine within the Machine

    CERN Multimedia

    Katarina Anthony

    2014-01-01

    Although Virtual Machines are widespread across CERN, you probably won't have heard of them unless you work for an experiment. Virtual machines - known as VMs - allow you to create a separate machine within your own, allowing you to run Linux on your Mac, or Windows on your Linux - whatever combination you need.   Using a CERN Virtual Machine, a Linux analysis software runs on a Macbook. When it comes to LHC data, one of the primary issues collaborations face is the diversity of computing environments among collaborators spread across the world. What if an institute cannot run the analysis software because they use different operating systems? "That's where the CernVM project comes in," says Gerardo Ganis, PH-SFT staff member and leader of the CernVM project. "We were able to respond to experimentalists' concerns by providing a virtual machine package that could be used to run experiment software. This way, no matter what hardware they have ...

  15. Machine translation

    Energy Technology Data Exchange (ETDEWEB)

    Nagao, M.

    1982-04-01

    Each language has its own structure. In translating one language into another one, language attributes and grammatical interpretation must be defined in an unambiguous form. In order to parse a sentence, it is necessary to recognize its structure. A so-called context-free grammar can help in this respect for machine translation and machine-aided translation. Problems to be solved in studying machine translation are taken up in the paper, which discusses subjects for semantics and for syntactic analysis and translation software. 14 references.

  16. Elastic scattering and reaction mechanisms of the halo nucleus $^{11}$Be around the Coulomb barrier

    CERN Document Server

    Di Pietro, A; Fisichella, M; Borge, M J G; Randisi, G; Milin, M; Figuera, P; Gomez-Camacho, J; Raabe, R; Amorini, F; Fraile, L M; Rizzo, F; Zadro, M; Torresi, D; Wenander, F; Pellegriti, M G; Papa, M; Jeppesen, H; Santonocito, D; Scuderi, V; Acosta, L; Perez-Bernal, F; Tengblad, O; Lattuada, M; Musumarra, A; Scalia, G; Maira Vidal, A; Voulot, D

    2010-01-01

    Collisions induced by $^{9}$Be, $^{10}$Be, $^{11}$Be on a $^{64}$Zn target at the same c. m. energy were studied. For the first time, strong effects of the $^{11}$Be halo structure on elastic-scattering and reaction mechanisms at energies near the Coulomb barrier are evidenced experimentally. The elastic-scattering cross section of the $^{11}$Be halo nucleus shows unusual behavior in the Coulomb-nuclear interference peak angular region. The extracted total-reaction cross section for the $^{11}$Be collision is more than double the ones measured in the collisions induced by $^{9}$Be, $^{10}$Be. It is shown that such a strong enhancement of the total-reaction cross section with $^{11}$Be is due to transfer and breakup processes.

  17. N-body dark matter haloes with simple hierarchical histories

    Science.gov (United States)

    Jiang, Lilian; Helly, John C.; Cole, Shaun; Frenk, Carlos S.

    2014-05-01

    We present a new algorithm which groups the subhaloes found in cosmological N-body simulations by structure finders such as SUBFIND into dark matter haloes whose formation histories are strictly hierarchical. One advantage of these `Dhaloes' over the commonly used friends-of-friends (FoF) haloes is that they retain their individual identity in the cases when FoF haloes are artificially merged by tenuous bridges of particles or by an overlap of their outer diffuse haloes. Dhaloes are thus well suited for modelling galaxy formation and their merger trees form the basis of the Durham semi-analytic galaxy formation model, GALFORM. Applying the Dhalo construction to the Λ cold dark matter Millennium II Simulation, we find that approximately 90 per cent of Dhaloes have a one-to-one, bijective match with a corresponding FoF halo. The remaining 10 per cent are typically secondary components of large FoF haloes. Although the mass functions of both types of haloes are similar, the mass of Dhaloes correlates much more tightly with the virial mass, M200, than FoF haloes. Approximately 80 per cent of FoF and bijective and non-bijective Dhaloes are relaxed according to standard criteria. For these relaxed haloes, all three types have similar concentration-M200 relations and, at fixed mass, the concentration distributions are described accurately by log-normal distributions.

  18. Reversed Halo Sign: Presents in Different Pulmonary Diseases.

    Directory of Open Access Journals (Sweden)

    Xi Zhan

    Full Text Available To observe the incidence of reversed halo sign in different pulmonary diseases and the pathological correspondence of reversed halo sign.Retrospectively studied the high resolution computer tomography scans of all the patients who were admitted in our department with abnormal pulmonary imaging, from 1st of January 2011 to 31st of December 2013, and all the cases with reversed halo sign on the high resolution computer tomography were collected. Clinical data such as pathological findings and confirmed diagnosis of the patients with reversed halo sign on the high resolution computer tomography scan were collected and summarized.Of 1546 abnormal High resolution computer tomography scans 108 had a reverse halo sign present, including 108 cases were observed with reversed halo sign in the high resolution computer tomography, including 40 cases of pulmonary tuberculosis, 43 cases of cryptogenic organizing pneumonia, 16 cases of lung cancer, 7 cases of sarcoidosis, and 1 case of pulmonary cryptococcosis, 1 case of granulomatosis with polyangiitis. Reversed halo sign had a higher incidence in granulomatous diseases (16.28% compared with non-granulomatous diseases (9.97%.Reversed halo sign is relatively non specific; it can be observed in different lung diseases, and different phases of diseases; reversed halo sign is more commonly found in granulomatous diseases compared with non-granulomatous diseases, and is most commonly observed in pulmonary tuberculosis among the granulomatous diseases, and in cryptogenic organizing pneumonia among the non-granulomatous diseases.

  19. Brightest galaxies as halo centre tracers in SDSS DR7

    Science.gov (United States)

    Lange, Johannes U.; van den Bosch, Frank C.; Hearin, Andrew; Campbell, Duncan; Zentner, Andrew R.; Villarreal, Antonio; Mao, Yao-Yuan

    2018-01-01

    Determining the positions of halo centres in large-scale structure surveys is crucial for many cosmological studies. A common assumption is that halo centres correspond to the location of their brightest member galaxies. In this paper, we study the dynamics of brightest galaxies with respect to other halo members in the Sloan Digital Sky Survey DR7. Specifically, we look at the line-of-sight velocity and spatial offsets between brightest galaxies and their neighbours. We compare those to detailed mock catalogues, constructed from high-resolution, dark-matter-only N-body simulations, in which it is assumed that satellite galaxies trace dark matter subhaloes. This allows us to place constraints on the fraction fBNC of haloes in which the brightest galaxy is not the central. Compared to previous studies, we explicitly take into account the unrelaxed state of the host haloes, velocity offsets of halo cores and correlations between fBNC and the satellite occupation. We find that fBNC strongly decreases with the luminosity of the brightest galaxy and increases with the mass of the host halo. Overall, in the halo mass range 1013-1014.5 h- 1M⊙ we find fBNC ∼ 30 per cent, in good agreement with a previous study by Skibba et al. We discuss the implications of these findings for studies inferring the galaxy-halo connection from satellite kinematics, models of the conditional luminosity function and galaxy formation in general.

  20. Mapping stellar content to dark matter haloes - II. Halo mass is the main driver of galaxy quenching

    Science.gov (United States)

    Zu, Ying; Mandelbaum, Rachel

    2016-04-01

    We develop a simple yet comprehensive method to distinguish the underlying drivers of galaxy quenching, using the clustering and galaxy-galaxy lensing of red and blue galaxies in Sloan Digital Sky Survey. Building on the iHOD framework developed by Zu & Mandelbaum, we consider two quenching scenarios: (1) a `halo' quenching model in which halo mass is the sole driver for turning off star formation in both centrals and satellites; and (2) a `hybrid' quenching model in which the quenched fraction of galaxies depends on their stellar mass, while the satellite quenching has an extra dependence on halo mass. The two best-fitting models describe the red galaxy clustering and lensing equally well, but halo quenching provides significantly better fits to the blue galaxies above 1011 h-2 M⊙. The halo quenching model also correctly predicts the average halo mass of the red and blue centrals, showing excellent agreement with the direct weak lensing measurements of locally brightest galaxies. Models in which quenching is not tied to halo mass, including an age-matching model in which galaxy colour depends on halo age at fixed M*, fail to reproduce the observed halo mass for massive blue centrals. We find similar critical halo masses responsible for the quenching of centrals and satellites (˜1.5 × 1012 h-1 M⊙), hinting at a uniform quenching mechanism for both, e.g. the virial shock heating of infalling gas. The success of the iHOD halo quenching model provides strong evidence that the physical mechanism that quenches star formation in galaxies is tied principally to the masses of their dark matter haloes rather than the properties of their stellar components.

  1. Machine Learning

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    Machine learning, which builds on ideas in computer science, statistics, and optimization, focuses on developing algorithms to identify patterns and regularities in data, and using these learned patterns to make predictions on new observations. Boosted by its industrial and commercial applications, the field of machine learning is quickly evolving and expanding. Recent advances have seen great success in the realms of computer vision, natural language processing, and broadly in data science. Many of these techniques have already been applied in particle physics, for instance for particle identification, detector monitoring, and the optimization of computer resources. Modern machine learning approaches, such as deep learning, are only just beginning to be applied to the analysis of High Energy Physics data to approach more and more complex problems. These classes will review the framework behind machine learning and discuss recent developments in the field.

  2. Clustering dark energy and halo abundances

    Science.gov (United States)

    Batista, Ronaldo C.; Marra, Valerio

    2017-11-01

    Within the standard paradigm, dark energy is taken as a homogeneous fluid that drives the accelerated expansion of the universe and does not contribute to the mass of collapsed objects such as galaxies and galaxy clusters. The abundance of galaxy clusters—measured through a variety of channels—has been extensively used to constrain the normalization of the power spectrum: it is an important probe as it allows us to test if the standard ΛCDM model can indeed accurately describe the evolution of structures across billions of years. It is then quite significant that the Planck satellite has detected, via the Sunyaev-Zel'dovich effect, less clusters than expected according to the primary CMB anisotropies. One of the simplest generalizations that could reconcile these observations is to consider models in which dark energy is allowed to cluster, i.e., allowing its sound speed to vary. In this case, however, the standard methods to compute the abundance of galaxy clusters need to be adapted to account for the contributions of dark energy. In particular, we examine the case of clustering dark energy—a dark energy fluid with negligible sound speed—with a redshift-dependent equation of state. We carefully study how the halo mass function is modified in this scenario, highlighting corrections that have not been considered before in the literature. We address modifications in the growth function, collapse threshold, virialization densities and also changes in the comoving scale of collapse and mass function normalization. Our results show that clustering dark energy can impact halo abundances at the level of 10%-30%, depending on the halo mass, and that cluster counts are modified by about 30% at a redshift of unity.

  3. Monel Machining

    Science.gov (United States)

    1983-01-01

    Castle Industries, Inc. is a small machine shop manufacturing replacement plumbing repair parts, such as faucet, tub and ballcock seats. Therese Castley, president of Castle decided to introduce Monel because it offered a chance to improve competitiveness and expand the product line. Before expanding, Castley sought NERAC assistance on Monel technology. NERAC (New England Research Application Center) provided an information package which proved very helpful. The NASA database was included in NERAC's search and yielded a wealth of information on machining Monel.

  4. Fast low-energy halo-to-halo transfers between Sun–planet systems

    Directory of Open Access Journals (Sweden)

    Shang Haibin

    2014-04-01

    Full Text Available In this paper, the problem of fast low-energy halo-to-halo transfers between Sun–planet systems is discussed under ephemeris constraints. According to the structure of an invariant manifold, employing an invariant manifold and planetary gravity assist to save fuel consumption is analyzed from the view of orbital energy. Then, a pseudo-manifold is introduced to replace the invariant manifold in such a way that more transfer opportunities are allowed. Fast escape and capture can be achieved along the pseudo-manifold. Furthermore, a global searching method that is based on patched-models is proposed to find an appropriate transfer trajectory. In this searching method, the trajectory is divided into several segments that can be designed under simple dynamical models, and an analytical algorithm is developed for connecting the segments. Earth–Mars and Earth–Venus halo-to-halo transfers are designed to demonstrate the proposed approach. Numerical results show that the transfers that combine the pseudo-manifolds and planetary gravity assist can offer significant fuel consumption and flight time savings over traditional transfer schemes.

  5. Haloes, molecules and multi-neutrons

    Energy Technology Data Exchange (ETDEWEB)

    Marques Moreno, F.M

    2003-01-01

    Away from the equilibrium between protons and neutrons within stable nuclei, many exotic nuclei exist. Most of the known nuclear properties evolve smoothly with exoticism, but some extreme proton-neutron combinations have revealed during the last decade completely new concepts. They will be illustrated through three examples: the extended and dilute halo formed by very weakly bound neutrons, the molecular-like neutron orbitals found in nuclei exhibiting a clustering, and the recently revived debate on the possible existence of neutral nuclei. The different experimental results will be reviewed, and we will see how several properties of these new phenomena can be well understood within relatively simple theoretical approaches. (author)

  6. Clustering and correlations in neutrons haloes

    Energy Technology Data Exchange (ETDEWEB)

    Orr, N.A

    2002-02-01

    In the present paper clustering and correlations within halo systems is explored. In particular, the application of neutron-neutron interferometry and Dalitz-plot type analyses is presented through the example provided by the dissociation of {sup 14}Be. A novel approach for producing and detection bound neutron clusters is also described. The observation of some 6 events with characteristics consistent with the liberation of a multi-neutron cluster in the breakup of {sup 14}Be - possibly in the channel {sup 10}Be+{sup 4}n - is discussed. (author)

  7. Project ECHO: Electronic Communications from Halo Orbit

    Science.gov (United States)

    Borrelli, Jason; Cooley, Bryan; Debole, Marcy; Hrivnak, Lance; Nielsen, Kenneth; Sangmeister, Gary; Wolfe, Matthew

    1994-01-01

    The design of a communications relay to provide constant access between the Earth and the far side of the Moon is presented. Placement of the relay in a halo orbit about the L2 Earth-Moon Lagrange point allows the satellite to maintain constant simultaneous communication between Earth and scientific payloads on the far side of the Moon. The requirements of NASA's Discovery-class missions adopted and modified for this design are: total project cost should not exceed $150 million excluding launch costs, launch must be provided by Delta-class vehicle, and the satellite should maintain an operational lifetime of 10 to 15 years. The spacecraft will follow a transfer trajectory to the L2 point, after launch by a Delta II 7925 vehicle in 1999. Low-level thrust is used for injection into a stationkeeping-free halo orbit once the spacecraft reaches the L2 point. The shape of this halo orbit is highly elliptical with the maximum excursion from the L2 point being 35000 km. A spun section and despun section connected through a bearing and power transfer assembly (BAPTA) compose the structure of the spacecraft. Communications equipment is placed on the despun section to provide for a stationary dual parabolic offset-feed array antenna system. The dual system is necessary to provide communications coverage during portions of maximum excursion on the halo orbit. Transmissions to the NASA Deep Space Network 34 m antenna include six channels (color video, two voice, scientific data from lunar payloads, satellite housekeeping and telemetry and uplinked commands) using the S- and X-bands. Four radioisotope thermoelectric generators (RTG's) provide a total of 1360 W to power onboard systems and any two of the four Hughes 13 cm ion thrusters at once. Output of the ion thrusters is approximately 17.8 mN each with xenon as the propellant. Presence of torques generated by solar pressure on the antenna dish require the addition of a 'skirt' extending from the spun section of the satellite

  8. Universal properties of dark matter halos.

    Science.gov (United States)

    Boyarsky, A; Neronov, A; Ruchayskiy, O; Tkachev, I

    2010-05-14

    We discuss the universal relation between density and size of observed dark matter halos that was recently shown to hold on a wide range of scales, from dwarf galaxies to galaxy clusters. Predictions of cold dark matter (ΛCDM) N-body simulations are consistent with this relation. We demonstrate that this property of ΛCDM can be understood analytically in the secondary infall model. Qualitative understanding given by this model provides a new way to predict which deviations from ΛCDM or large-scale modifications of gravity can affect universal behavior and, therefore, to constrain them observationally.

  9. Stellar Mass—Halo Mass Relation and Star Formation Efficiency in High-Mass Halos

    Science.gov (United States)

    Kravtsov, A. V.; Vikhlinin, A. A.; Meshcheryakov, A. V.

    2018-01-01

    We study relation between stellar mass and halo mass for high-mass halos using a sample of galaxy clusters with accurate measurements of stellar masses from optical and ifrared data and total masses from X-ray observations. We find that stellar mass of the brightest cluster galaxies (BCGs) scales as M *,BCG ∝ M 500 αBCG with the best fit slope of α BCG ≈ 0.4 ± 0.1. We measure scatter of M *,BCG at a fixed M 500 of ≈0.2 dex. We show that stellar mass-halo mass relations from abundance matching or halo modelling reported in recent studies underestimate masses of BCGs by a factor of ˜2-4. We argue that this is because these studies used stellar mass functions (SMF) based on photometry that severely underestimates the outer surface brightness profiles of massive galaxies. We show that M * -M relation derived using abundance matching with the recent SMF calibration by Bernardi et al. (2013) based on improved photometry is in a much better agreement with the relation we derive via direct calibration for observed clusters. The total stellar mass of galaxies correlates with total mass M 500 with the slope of ≈0.6 ± 0.1 and scatter of 0.1 dex. This indicates that efficiency with which baryons are converted into stars decreases with increasing cluster mass. The low scatter is due to large contribution of satellite galaxies: the stellar mass in satellite galaxies correlates with M 500 with scatter of ≈0.1 dex and best fit slope of αsat ≈ 0.8 ± 0.1. We show that for a fixed choice of the initial mass function (IMF) total stellar fraction in clusters is only a factor of 3-5 lower than the peak stellar fraction reached in M ≈ 1012 M ⊙ halos. The difference is only a factor of ˜1.5-3 if the IMF becomes progressively more bottom heavy with increasing mass in early type galaxies, as indicated by recent observational analyses. This means that the overall efficiency of star formation in massive halos is only moderately suppressed compared to L * galaxies and

  10. Paradigms for machine learning

    Science.gov (United States)

    Schlimmer, Jeffrey C.; Langley, Pat

    1991-01-01

    Five paradigms are described for machine learning: connectionist (neural network) methods, genetic algorithms and classifier systems, empirical methods for inducing rules and decision trees, analytic learning methods, and case-based approaches. Some dimensions are considered along with these paradigms vary in their approach to learning, and the basic methods are reviewed that are used within each framework, together with open research issues. It is argued that the similarities among the paradigms are more important than their differences, and that future work should attempt to bridge the existing boundaries. Finally, some recent developments in the field of machine learning are discussed, and their impact on both research and applications is examined.

  11. Sources of machine-induced background in the ATLAS and CMS detectors at the CERN Large Hadron Collider

    CERN Document Server

    AUTHOR|(CDS)2068843; Boccone, V; Bregliozzi, G; Burkhardt, H; Cerutti, F; Ferrari, A; Huhtinen, M.; Lechner, A; Levinsen, Y; Mereghetti, A; Mokhov, N.V; Tropin, I.S; Vlachoudis, V

    2013-01-01

    One source of experimental background in the CERN Large Hadron Collider (LHC) is particles entering the detectors from the machine. These particles are created in cascades, caused by upstream interactions of beam protons with residual gas molecules or collimators. We estimate the losses on the collimators with SixTrack and simulate the showers with FLUKA and MARS to obtain the flux and distribution of particles entering the ATLAS and CMS detectors. We consider some machine configurations used in the first LHC run, with focus on 3.5 TeV operation as in 2011. Results from FLUKA and MARS are compared and a very good agreement is found. An analysis of logged LHC data provides, for different processes, absolute beam loss rates, which are used together with further simulations of vacuum conditions to normalize the results to rates of particles entering the detectors. We assess the relative importance of background from elastic and inelastic beam-gas interactions, and the leakage out of the LHC collimation system, a...

  12. The Prevalence of the 22 deg Halo in Cirrus Clouds

    Science.gov (United States)

    Diedenhoven, vanBastiaan

    2014-01-01

    Halos at 22 deg from the sun attributed to randomly-orientated, pristine hexagonal crystals are frequently observed through ice clouds. These frequent sightings of halos formed by pristine crystals pose an apparent inconsistency with the dominance of distorted, nonpristine ice crystals indicated by in situ and remote sensing data. Furthermore, the 46 deg halo, which is associated with pristine hexagonal crystals as well, is observed far less frequently than the 22 deg halo. Considering that plausible mechanisms that could cause crystal distortion such as aggregation, sublimation, riming and collisions are stochastic processes that likely lead to distributions of crystals with varying distortion levels, here the presence of the 22 deg and 46 deg halo features in phase functions of mixtures of pristine and distorted hexagonal ice crystals is examined. We conclude that the 22 deg halo feature is generally present if the contribution by pristine crystals to the total scattering cross section is greater than only about 10% in the case of compact particles or columns, and greater than about 40% for plates. The 46 deg halo feature is present only if the mean distortion level is low and the contribution of pristine crystals to the total scattering cross section is above about 20%, 50% and 70%, in the case of compact crystals, plates and columns, respectively. These results indicate that frequent sightings of 22 deg halos are not inconsistent with the observed dominance of distorted, non-pristine ice crystals. Furthermore, the low mean distortion levels and large contributions by pristine crystals needed to produce the 461 halo features provide a potential explanation of the common sighting of the 22 deg halo without any detectable 46 deg halo.

  13. Diverse stellar haloes in nearby Milky Way mass disc galaxies

    Science.gov (United States)

    Harmsen, Benjamin; Monachesi, Antonela; Bell, Eric F.; de Jong, Roelof S.; Bailin, Jeremy; Radburn-Smith, David J.; Holwerda, Benne W.

    2017-04-01

    We have examined the resolved stellar populations at large galactocentric distances along the minor axis (from 10 kpc up to between 40 and 75 kpc), with limited major axis coverage, of six nearby highly inclined Milky Way (MW) mass disc galaxies using Hubble Space Telescope data from the Galaxy haloes, Outer discs, Substructure, Thick discs, and Star clusters (GHOSTS) survey. We select red giant branch stars to derive stellar halo density profiles. The projected minor axis density profiles can be approximated by power laws with projected slopes of -2 to -3.7 and a diversity of stellar halo masses of 1-6 × 109 M⊙, or 2-14 per cent of the total galaxy stellar masses. The typical intrinsic scatter around a smooth power-law fit is 0.05-0.1 dex owing to substructure. By comparing the minor and major axis profiles, we infer projected axis ratios c/a at ˜25 kpc between 0.4and0.75. The GHOSTS stellar haloes are diverse, lying between the extremes charted out by the (rather atypical) haloes of the MW and M31. We find a strong correlation between the stellar halo metallicities and the stellar halo masses. We compare our results with cosmological models, finding good agreement between our observations and accretion-only models where the stellar haloes are formed by the disruption of dwarf satellites. In particular, the strong observed correlation between stellar halo metallicity and mass is naturally reproduced. Low-resolution hydrodynamical models have unrealistically high stellar halo masses. Current high-resolution hydrodynamical models appear to predict stellar halo masses somewhat higher than observed but with reasonable metallicities, metallicity gradients, and density profiles.

  14. 77 FR 75672 - Manufacturer of Controlled Substances, Notice of Registration, Halo Pharmaceutical, Inc.

    Science.gov (United States)

    2012-12-21

    ... Enforcement Administration Manufacturer of Controlled Substances, Notice of Registration, Halo Pharmaceutical... 47114, Halo Pharmaceutical, Inc., 30 North Jefferson Road, Whippany, New Jersey 07981, made application... determined that the registration of Halo Pharmaceutical, Inc., to manufacture the listed basic classes of...

  15. 77 FR 16264 - Manufacturer of Controlled Substances, Notice of Registration; Halo Pharmaceutical Inc.

    Science.gov (United States)

    2012-03-20

    ... Enforcement Administration Manufacturer of Controlled Substances, Notice of Registration; Halo Pharmaceutical... FR 77850, Halo Pharmaceutical Inc., 30 North Jefferson Road, Whippany, New Jersey 07981, made... determined that the registration of Halo Pharmaceutical Inc. to manufacture the listed basic classes of...

  16. Convergence properties of halo merger trees; halo and substructure merger rates across cosmic history

    Science.gov (United States)

    Poole, Gregory B.; Mutch, Simon J.; Croton, Darren J.; Wyithe, Stuart

    2017-12-01

    We introduce GBPTREES: an algorithm for constructing merger trees from cosmological simulations, designed to identify and correct for pathological cases introduced by errors or ambiguities in the halo finding process. GBPTREES is built upon a halo matching method utilizing pseudo-radial moments constructed from radially sorted particle ID lists (no other information is required) and a scheme for classifying merger tree pathologies from networks of matches made to-and-from haloes across snapshots ranging forward-and-backward in time. Focusing on SUBFIND catalogues for this work, a sweep of parameters influencing our merger tree construction yields the optimal snapshot cadence and scanning range required for converged results. Pathologies proliferate when snapshots are spaced by ≲0.128 dynamical times; conveniently similar to that needed for convergence of semi-analytical modelling, as established by Benson et al. Total merger counts are converged at the level of ∼5 per cent for friends-of-friends (FoF) haloes of size np ≳ 75 across a factor of 512 in mass resolution, but substructure rates converge more slowly with mass resolution, reaching convergence of ∼10 per cent for np ≳ 100 and particle mass mp ≲ 109 M⊙. We present analytic fits to FoF and substructure merger rates across nearly all observed galactic history (z ≤ 8.5). While we find good agreement with the results presented by Fakhouri et al. for FoF haloes, a slightly flatter dependence on merger ratio and increased major merger rates are found, reducing previously reported discrepancies with extended Press-Schechter estimates. When appropriately defined, substructure merger rates show a similar mass ratio dependence as FoF rates, but with stronger mass and redshift dependencies for their normalization.

  17. Alternative techniques for beam halo measurements

    CERN Document Server

    Welsch, CP; Burel, B; Lefèvre, T; Chapman, T; Pilon, MJ

    2006-01-01

    In future high intensity, high energy accelerators it must be ensured that particle losses are minimized, as activation of the vacuum chambers or other components makes maintenance and upgrade work time consuming and costly. It is imperative to have a clear understanding of the mechanisms that can lead to halo formation and to have the possibility to test available theoretical models with an adequate experimental setup. Measurements based on optical transition radiation (OTR) are a well-established technique for measurements of the transverse beam profile. However, in order to be suitable for halo measurements as well, the dynamic range of the final image acquisition system needs to be high, being able to cover at least five orders of magnitude in intensity changes. Here, the performance of a standard acquisition system as it is used in the CLIC test facility (CTF3) is compared to a step-by-step measurement with a small movable photo multiplier tube and an innovative camera system based on charge injection de...

  18. A 500 PARSEC HALO SURROUNDING THE GALACTIC GLOBULAR NGC 1851

    NARCIS (Netherlands)

    Olszewski, Edward W.; Saha, Abhijit; Knezek, Patricia; Subramaniam, Annapurni; de Boer, Thomas; Seitzer, Patrick

    2009-01-01

    Using imaging that shows 4 mag of main-sequence stars, we have discovered that the Galactic globular cluster NGC 1851 is surrounded by a halo that is visible from the tidal radius of 700 arcsec (41 pc) to more than 4500 arcsec (> 250 pc). This halo is symmetric and falls in density as a power law of

  19. Is the dark halo of our Galaxy spherical?

    NARCIS (Netherlands)

    Helmi, A

    2004-01-01

    It has been recently claimed that the confined structure of the debris from the Sagittarius dwarf implies that the dark matter halo of our Galaxy should be nearly spherical, in strong contrast with predictions from cold dark matter simulations, where dark haloes are found to have typical density

  20. Investigating Halo and Ceiling Effects in Student Evaluations of Instruction

    Science.gov (United States)

    Keeley, Jared W.; English, Taylor; Irons, Jessica; Henslee, Amber M.

    2013-01-01

    Many measurement biases affect student evaluations of instruction (SEIs). However, two have been relatively understudied: halo effects and ceiling/floor effects. This study examined these effects in two ways. To examine the halo effect, using a videotaped lecture, we manipulated specific teacher behaviors to be "good" or "bad"…

  1. Binary white dwarfs in the halo of the Milky Way

    NARCIS (Netherlands)

    van Oirschot, Pim; Nelemans, Gijs; Toonen, Silvia; Pols, Onno; Brown, Anthony G. A.; Helmi, Amina; Portegies Zwart, Simon

    Aims: We study single and binary white dwarfs in the inner halo of the Milky Way in order to learn more about the conditions under which the population of halo stars was born, such as the initial mass function (IMF), the star formation history, or the binary fraction. Methods: We simulate the

  2. Disk response to a lopsided halo potential (Jog 1997, 2002):

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Disk response to a lopsided halo potential (Jog 1997, 2002):. consider small (few %) perturbation in potential. --- solve equations of motion using epicyclic theory. The symmetric disk potential = ψ_0 (R ) = Vc 2 ln R. and the perturbation halo potential = Vc 2 εlop cos φ ...

  3. THE COSMOGRID SIMULATION: STATISTICAL PROPERTIES OF SMALL DARK MATTER HALOS

    Energy Technology Data Exchange (ETDEWEB)

    Ishiyama, Tomoaki [Center for Computational Science, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki 305-8577 (Japan); Rieder, Steven; Portegies Zwart, Simon [Sterrewacht Leiden, Leiden University, P.O. Box 9513, 2300-RA Leiden (Netherlands); Makino, Junichiro [Graduate School of Science and Engineering, Tokyo Institute of Technology (Japan); Groen, Derek [Centre for Computational Science, Department of Chemistry, University College London, 20 Gordon Street, London, WC1H 0AJ (United Kingdom); Nitadori, Keigo [RIKEN Advanced Institute for Computational Science (Japan); De Laat, Cees [Section System and Network Engineering, University of Amsterdam, Amsterdam (Netherlands); McMillan, Stephen [Department of Physics, Drexel University, Philadelphia, PA 19104 (United States); Hiraki, Kei [Department of Creative Informatics, Graduate School of Information Science and Technology, the University of Tokyo (Japan); Harfst, Stefan, E-mail: ishiyama@ccs.tsukuba.ac.jp [Center for Astronomy and Astrophysics, Technical University Berlin, Hardenbergstr. 36, D-10623 Berlin (Germany)

    2013-04-20

    We present the results of the ''Cosmogrid'' cosmological N-body simulation suites based on the concordance LCDM model. The Cosmogrid simulation was performed in a 30 Mpc box with 2048{sup 3} particles. The mass of each particle is 1.28 Multiplication-Sign 10{sup 5} M{sub Sun }, which is sufficient to resolve ultra-faint dwarfs. We found that the halo mass function shows good agreement with the Sheth and Tormen fitting function down to {approx}10{sup 7} M{sub Sun }. We have analyzed the spherically averaged density profiles of the three most massive halos which are of galaxy group size and contain at least 170 million particles. The slopes of these density profiles become shallower than -1 at the innermost radius. We also find a clear correlation of halo concentration with mass. The mass dependence of the concentration parameter cannot be expressed by a single power law, however a simple model based on the Press-Schechter theory proposed by Navarro et al. gives reasonable agreement with this dependence. The spin parameter does not show a correlation with the halo mass. The probability distribution functions for both concentration and spin are well fitted by the log-normal distribution for halos with the masses larger than {approx}10{sup 8} M{sub Sun }. The subhalo abundance depends on the halo mass. Galaxy-sized halos have 50% more subhalos than {approx}10{sup 11} M{sub Sun} halos have.

  4. The Cosmogrid Simulation: Statistical Properties of Small Dark Matter Halos

    Science.gov (United States)

    Ishiyama, Tomoaki; Rieder, Steven; Makino, Junichiro; Portegies Zwart, Simon; Groen, Derek; Nitadori, Keigo; de Laat, Cees; McMillan, Stephen; Hiraki, Kei; Harfst, Stefan

    2013-04-01

    We present the results of the "Cosmogrid" cosmological N-body simulation suites based on the concordance LCDM model. The Cosmogrid simulation was performed in a 30 Mpc box with 20483 particles. The mass of each particle is 1.28 × 105 M ⊙, which is sufficient to resolve ultra-faint dwarfs. We found that the halo mass function shows good agreement with the Sheth & Tormen fitting function down to ~107 M ⊙. We have analyzed the spherically averaged density profiles of the three most massive halos which are of galaxy group size and contain at least 170 million particles. The slopes of these density profiles become shallower than -1 at the innermost radius. We also find a clear correlation of halo concentration with mass. The mass dependence of the concentration parameter cannot be expressed by a single power law, however a simple model based on the Press-Schechter theory proposed by Navarro et al. gives reasonable agreement with this dependence. The spin parameter does not show a correlation with the halo mass. The probability distribution functions for both concentration and spin are well fitted by the log-normal distribution for halos with the masses larger than ~108 M ⊙. The subhalo abundance depends on the halo mass. Galaxy-sized halos have 50% more subhalos than ~1011 M ⊙ halos have.

  5. A two-point correlation function for Galactic halo stars

    NARCIS (Netherlands)

    Cooper, A. P.; Cole, S.; Frenk, C. S.; Helmi, A.

    2011-01-01

    We describe a correlation function statistic that quantifies the amount of spatial and kinematic substructure in the stellar halo. We test this statistic using model stellar halo realizations constructed from the Aquarius suite of six high-resolution cosmological N-body simulations, in combination

  6. Influence of halo doping profiles on MOS transistor mismatch

    NARCIS (Netherlands)

    Andricciola, P.; Tuinhout, H.

    2009-01-01

    Halo implants are used in modern CMOS technology to reduce the short channel effect. However, the lateral non-uniformity of the channel doping has been proven to degenerate the mismatch performance. With this paper we want to discuss the influence of the halo profile on MOS transistor mismatch. The

  7. A Hidden Radio Halo in the Galaxy Cluster A1682?

    Indian Academy of Sciences (India)

    High sensitivity observations of radio halos in galaxy clusters at frequencies ≤ 330 MHz are still relatively rare, and very little is known compared to the classical 1.4 GHz images. The few radio halos imaged down to 150–240 MHz show a considerable spread in size, morphology and spectral properties. All clusters ...

  8. Double folding model analysis of elastic scattering of halo nucleus ...

    Indian Academy of Sciences (India)

    features of halo nuclei largely affect the interaction with light and heavy targets at low bombarding energies and have created tremendous interest in the study of nuclear reac- tions. Elastic scattering is sensitive to the nature of the surface of nuclei and hence it is effective in studying halo nuclei. Pramana – J. Phys., Vol.

  9. The Connection between Radio Halos and Cluster Mergers and the ...

    Indian Academy of Sciences (India)

    We discuss the statistical properties of the radio halo population in galaxy clusters. Radio bi-modality is observed in galaxy clusters: a fraction of clusters host giant radio halos while a majority of clusters do not show evidence of diffuse cluster-scale radio emission. The radio bi-modality has a correspondence in terms of ...

  10. RR Lyrae to build up the Galactic Halo

    Science.gov (United States)

    Fiorentino, Giuliana

    2015-08-01

    We compare the period and period-amplitude distributions for a sizeable sample of rrab in dwarfs (~1300stars) with those in the galactic halo (~14,000stars) and globular clusters (~1000stars). Field rrab show a significant change in their period distribution when moving from the inner (dg~14kpc) halo regions, suggesting that the halo formed from (at least) two dissimilar progenitors or events. Rrab in dwarfs-as observed today-do not appear to follow the pulsation properties shown by those in the galactic halo, nor do they have the same properties as rrls in globulars. Only massive and metal rich satellites likely have mainly contributed to the galactic halo formation, e.g. Sgr dSph.

  11. Machine learning and cosmological simulations - I. Semi-analytical models

    Science.gov (United States)

    Kamdar, Harshil M.; Turk, Matthew J.; Brunner, Robert J.

    2016-01-01

    We present a new exploratory framework to model galaxy formation and evolution in a hierarchical Universe by using machine learning (ML). Our motivations are two-fold: (1) presenting a new, promising technique to study galaxy formation, and (2) quantitatively analysing the extent of the influence of dark matter halo properties on galaxies in the backdrop of semi-analytical models (SAMs). We use the influential Millennium Simulation and the corresponding Munich SAM to train and test various sophisticated ML algorithms (k-Nearest Neighbors, decision trees, random forests, and extremely randomized trees). By using only essential dark matter halo physical properties for haloes of M > 1012 M⊙ and a partial merger tree, our model predicts the hot gas mass, cold gas mass, bulge mass, total stellar mass, black hole mass and cooling radius at z = 0 for each central galaxy in a dark matter halo for the Millennium run. Our results provide a unique and powerful phenomenological framework to explore the galaxy-halo connection that is built upon SAMs and demonstrably place ML as a promising and a computationally efficient tool to study small-scale structure formation.

  12. Machine Protection

    CERN Document Server

    Zerlauth, Markus; Wenninger, Jörg

    2012-01-01

    The present architecture of the machine protection system is being recalled and the performance of the associated systems during the 2011 run will be briefly summarized. An analysis of the causes of beam dumps as well as an assessment of the dependability of the machine protection systems (MPS) itself is being presented. Emphasis will be given to events that risked exposing parts of the machine to damage. Further improvements and mitigations of potential holes in the protection systems will be evaluated along with their impact on the 2012 run. The role of rMPP during the various operational phases (commissioning, intensity ramp up, MDs...) will be discussed along with a proposal for the intensity ramp up for the start of beam operation in 2012.

  13. Machine Learning

    Energy Technology Data Exchange (ETDEWEB)

    Chikkagoudar, Satish; Chatterjee, Samrat; Thomas, Dennis G.; Carroll, Thomas E.; Muller, George

    2017-04-21

    The absence of a robust and unified theory of cyber dynamics presents challenges and opportunities for using machine learning based data-driven approaches to further the understanding of the behavior of such complex systems. Analysts can also use machine learning approaches to gain operational insights. In order to be operationally beneficial, cybersecurity machine learning based models need to have the ability to: (1) represent a real-world system, (2) infer system properties, and (3) learn and adapt based on expert knowledge and observations. Probabilistic models and Probabilistic graphical models provide these necessary properties and are further explored in this chapter. Bayesian Networks and Hidden Markov Models are introduced as an example of a widely used data driven classification/modeling strategy.

  14. Binary white dwarfs in the halo of the Milky Way

    Science.gov (United States)

    van Oirschot, Pim; Nelemans, Gijs; Toonen, Silvia; Pols, Onno; Brown, Anthony G. A.; Helmi, Amina; Portegies Zwart, Simon

    2014-09-01

    Aims: We study single and binary white dwarfs in the inner halo of the Milky Way in order to learn more about the conditions under which the population of halo stars was born, such as the initial mass function (IMF), the star formation history, or the binary fraction. Methods: We simulate the evolution of low-metallicity halo stars at distances up to ~3 kpc using the binary population synthesis code SeBa. We use two different white dwarf cooling models to predict the present-day luminosities of halo white dwarfs. We determine the white dwarf luminosity functions (WDLFs) for eight different halo models and compare these with the observed halo WDLF of white dwarfs in the SuperCOSMOS Sky Survey. Furthermore, we predict the properties of binary white dwarfs in the halo and determine the number of halo white dwarfs that is expected to be observed with the Gaia satellite. Results: By comparing the WDLFs, we find that a standard IMF matches the observations more accurately than a top-heavy one, but the difference with a bottom-heavy IMF is small. A burst of star formation 13 Gyr ago fits slightly better than a star formation burst 10 Gyr ago and also slightly better than continuous star formation 10-13 Gyr ago. Gaia will be the first instument to constrain the bright end of the field halo WDLF, where contributions from binary WDs are considerable. Many of these will have He cores, of which a handful have atypical surface gravities (log g 0 in our standard model for WD cooling. These so called pre-WDs, if observed, can help us to constrain white dwarf cooling models and might teach us something about the fraction of halo stars that reside in binaries. Appendices are available in electronic form at http://www.aanda.org

  15. What sets the central structure of dark matter haloes?

    Science.gov (United States)

    Ogiya, Go; Hahn, Oliver

    2018-02-01

    Dark matter (DM) haloes forming near the thermal cut-off scale of the density perturbations are unique, since they are the smallest objects and form through monolithic gravitational collapse, while larger haloes contrastingly have experienced mergers. While standard cold dark matter (CDM) simulations readily produce haloes that follow the universal Navarro-Frenk-White (NFW) density profile with an inner slope, ρ ∝ r-α, with α = 1, recent simulations have found that when the free-streaming cut-off expected for the CDM model is resolved, the resulting haloes follow nearly power-law density profiles of α ∼ 1.5. In this paper, we study the formation of density cusps in haloes using idealized N-body simulations of the collapse of proto-haloes. When the proto-halo profile is initially cored due to particle free-streaming at high redshift, we universally find ∼r-1.5 profiles irrespective of the proto-halo profile slope outside the core and large-scale non-spherical perturbations. Quite in contrast, when the proto-halo has a power-law profile, then we obtain profiles compatible with the NFW shape when the density slope of the proto-halo patch is shallower than a critical value, αini ∼ 0.3, while the final slope can be steeper for αini ≳ 0.3. We further demonstrate that the r-1.5 profiles are sensitive to small-scale noise, which gradually drives them towards an inner slope of -1, where they become resilient to such perturbations. We demonstrate that the r-1.5 solutions are in hydrostatic equilibrium, largely consistent with a simple analytic model, and provide arguments that angular momentum appears to determine the inner slope.

  16. Predictive Toxicology: Modeling Chemical Induced Toxicological Response Combining Circular Fingerprints with Random Forest and Support Vector Machine

    Directory of Open Access Journals (Sweden)

    Alexios eKoutsoukas

    2016-03-01

    Full Text Available Modern drug discovery and toxicological research are under pressure, as the cost of developing and testing new chemicals for potential toxicological risk is rising. Extensive evaluation of chemical products for potential adverse effects is a challenging task, due to the large number of chemicals and the possible hazardous effects on human health. Safety regulatory agencies around the world are dealing with two major challenges. First, the growth of chemicals introduced every year in household products and medicines that need to be tested, and second the need to protect public welfare. Hence, alternative and more efficient toxicological risk assessment methods are in high demand. The Toxicology in the 21st Century (Tox21 consortium a collaborative effort was formed to develop and investigate alternative assessment methods. A collection of 10,000 compounds composed of environmental chemicals and approved drugs were screened for interference in biochemical pathways and released for crowdsourcing data analysis. The physicochemical space covered by Tox21 library was explored, measured by Molecular Weight (MW and the octanol/water partition coefficient (cLogP. It was found that on average chemical structures had MW of 272.6 Daltons. In case of cLogP the average value was 2.476. Next relationships between assays were examined based on compounds activity profiles across the assays utilizing the Pearson correlation coefficient r. A cluster was observed between the Androgen and Estrogen Receptors and their ligand bind domains accordingly indicating presence of cross talks among the receptors. The highest correlations observed were between NR.AR and NR.AR_LBD, where it was r=0.66 and between NR.ER and NR.ER_LBD, where it was r=0.5.Our approach to model the Tox21 data consisted of utilizing circular molecular fingerprints combined with Random Forest and Support Vector Machine by modeling each assay independently. In all of the 12 sub-challenges our modeling

  17. The Outer Halo of the Milky Way as Probed by RR Lyr Variables from the Palomar Transient Facility

    Science.gov (United States)

    Cohen, Judith G.; Sesar, Branimir; Bahnolzer, Sophianna; He, Kevin; Kulkarni, Shrinivas R.; Prince, Thomas A.; Bellm, Eric; Laher, Russ R.

    2017-11-01

    RR Lyrae stars are ideal massless tracers that can be used to study the total mass and dark matter content of the outer halo of the Milky Way (MW). This is because they are easy to find in the light-curve databases of large stellar surveys and their distances can be determined with only knowledge of the light curve. We present here a sample of 112 RR Lyr stars beyond 50 kpc in the outer halo of the MW, excluding the Sgr streams, for which we have obtained moderate-resolution spectra with Deimos on the Keck II Telescope. Four of these have distances exceeding 100 kpc. These were selected from a much larger set of 447 candidate RR Lyr stars that were data-mined using machine-learning techniques applied to the light curves of variable stars in the Palomar Transient Facility database. The observed radial velocities taken at the phase of the variable corresponding to the time of observation were converted to systemic radial velocities in the Galactic standard of rest. From our sample of 112 RR Lyr stars we determine the radial velocity dispersion in the outer halo of the MW to be ∼90 km s‑1 at 50 kpc, falling to about 65 km s‑1 near 100 kpc once a small number of major outliers are removed. With reasonable estimates of the completeness of our sample of 447 candidates and assuming a spherical halo, we find that the stellar density in the outer halo declines as {r}-4. Based in part on observations obtained at the W. M. Keck Observatory, which is operated jointly by the California Institute of Technology, the University of California, and the National Aeronautics and Space Administration.

  18. Never smile at a crocodile: betting on electronic gaming machines is intensified by reptile-induced arousal.

    Science.gov (United States)

    Rockloff, Matthew J; Greer, Nancy

    2010-12-01

    Tourists at the Koorana Saltwater Crocodile Farm in Coowonga, Queensland, Australia, including 62 males and 41 females, aged 18-66 (M = 34.2, SD = 13.3), were randomly assigned to play a laptop-simulated Electronic Gaming Machine (EGM) either: (1) prior to entry, or (2) after having held a 1-m saltwater-crocodile. Gambling behavior; including bet-size, speed of betting, final payouts and trials played on the EGM; was investigated with respect to participants' assigned arousal condition, problem-gambling status, and affective state. At-risk gamblers with few self-reported negative emotions placed higher average bets at the EGM after having held the crocodile when compared to the control. In contrast, at-risk gamblers with many self-reported negative emotions placed lower average bets at the EGM after having held the crocodile. The results suggest that high arousal can intensify gambling in at-risk players, but only if this feeling state is not perceived as a negative emotion.

  19. Machine testning

    DEFF Research Database (Denmark)

    De Chiffre, Leonardo

    This document is used in connection with a laboratory exercise of 3 hours duration as a part of the course GEOMETRICAL METROLOGY AND MACHINE TESTING. The exercise includes a series of tests carried out by the student on a conventional and a numerically controled lathe, respectively. This document...

  20. Representational Machines

    DEFF Research Database (Denmark)

    Petersson, Dag; Dahlgren, Anna; Vestberg, Nina Lager

    to the enterprises of the medium. This is the subject of Representational Machines: How photography enlists the workings of institutional technologies in search of establishing new iconic and social spaces. Together, the contributions to this edited volume span historical epochs, social environments, technological...

  1. Historic halo displays as weather indicator: Criteria and examples

    Science.gov (United States)

    Neuhäuser, Dagmar L.; Neuhäuser, Ralph

    2016-04-01

    There are numerous celestial signs reported in historic records, many of them refer to atmospheric ("sub-lunar") phenomena, such as ice halos and aurorae. In an interdisciplinary collaboration between astrophysics and cultural astronomy, we noticed that celestial observations including meteorological phenomena are often misinterpreted, mostly due to missing genuine criteria: especially ice crystal halos were recorded frequently in past centuries for religious reasons, but are mistaken nowadays often for other phenomena like aurorae. Ice halo displays yield clear information on humidity and temperature in certain atmospheric layers, and thereby indicate certain weather patterns. Ancient so-called rain makers used halo observations for weather forecast; e.g., a connection between certain halo displays and rain a few day later is statistically significant. Ice halos exist around sun and moon and are reported for both (they can stay for several days): many near, middle, and far eastern records from day- and night-time include such observations with high frequency. (Partly based on publications on halos by D.L. Neuhäuser & R. Neuhäuser, available at http://www.astro.uni-jena.de/index.php/terra-astronomy.html)

  2. Accurate mass and velocity functions of dark matter haloes

    Science.gov (United States)

    Comparat, Johan; Prada, Francisco; Yepes, Gustavo; Klypin, Anatoly

    2017-08-01

    N-body cosmological simulations are an essential tool to understand the observed distribution of galaxies. We use the MultiDark simulation suite, run with the Planck cosmological parameters, to revisit the mass and velocity functions. At redshift z = 0, the simulations cover four orders of magnitude in halo mass from ˜1011M⊙ with 8783 874 distinct haloes and 532 533 subhaloes. The total volume used is ˜515 Gpc3, more than eight times larger than in previous studies. We measure and model the halo mass function, its covariance matrix w.r.t halo mass and the large-scale halo bias. With the formalism of the excursion-set mass function, we explicit the tight interconnection between the covariance matrix, bias and halo mass function. We obtain a very accurate (Planck cosmology. Finally, we provide precise analytical fits of the Vmax maximum velocity function up to redshift z < 2.3 to push for the development of halo occupation distribution using Vmax. The data and the analysis code are made publicly available in the Skies and Universes data base.

  3. Chemical Cartography. I. A Carbonicity Map of the Galactic Halo

    Science.gov (United States)

    Lee, Young Sun; Beers, Timothy C.; Kim, Young Kwang; Placco, Vinicius; Yoon, Jinmi; Carollo, Daniela; Masseron, Thomas; Jung, Jaehun

    2017-02-01

    We present the first map of carbonicity, [C/Fe], for the halo system of the Milky Way, based on a sample of over 100,000 main-sequence turnoff stars with available spectroscopy from the Sloan Digital Sky Survey. This map, which explores distances up to 15 kpc from the Sun, reveals clear evidence for the dual nature of the Galactic halo, based on the spatial distribution of stellar carbonicity. The metallicity distribution functions of stars in the inner- and outer-halo regions of the carbonicity map reproduce those previously argued to arise from contributions of the inner- and outer-halo populations, with peaks at [Fe/H] = -1.5 and -2.2, respectively. From consideration of the absolute carbon abundances for our sample, A(C), we also confirm that the carbon-enhanced metal-poor (CEMP) stars in the outer-halo region exhibit a higher frequency of CEMP-no stars (those with no overabundances of heavy neutron-capture elements) than of CEMP-s stars (those with strong overabundances of elements associated with the s-process), whereas the stars in the inner-halo region exhibit a higher frequency of CEMP-s stars. We argue that the contrast in the behavior of the CEMP-no and CEMP-s fractions in these regions arises from differences in the mass distributions of the mini-halos from which the stars of the inner- and outer-halo populations formed, which gives rise in turn to the observed dichotomy of the Galactic halo.

  4. Chemical Cartography. I. A Carbonicity Map of the Galactic Halo

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Young Sun; Kim, Young Kwang [Department of Astronomy and Space Science, Chungnam National University, Daejeon 34134 (Korea, Republic of); Beers, Timothy C.; Placco, Vinicius; Yoon, Jinmi [Department of Physics and JINA Center for the Evolution of the Elements, University of Notre Dame, Notre Dame, IN 46556 (United States); Carollo, Daniela [Research School of Astronomy and Astrophysics, The Australian National University, Canberra, ACT 2611 (Australia); Masseron, Thomas [Institute of Astronomy, University of Cambridge, Madingley Road, Cambridge CB3 0HA (United Kingdom); Jung, Jaehun, E-mail: youngsun@cnu.ac.kr [Department of Astronomy, Space Science, and Geology, Chungnam National University, Daejeon 34134 (Korea, Republic of)

    2017-02-10

    We present the first map of carbonicity, [C/Fe], for the halo system of the Milky Way, based on a sample of over 100,000 main-sequence turnoff stars with available spectroscopy from the Sloan Digital Sky Survey. This map, which explores distances up to 15 kpc from the Sun, reveals clear evidence for the dual nature of the Galactic halo, based on the spatial distribution of stellar carbonicity. The metallicity distribution functions of stars in the inner- and outer-halo regions of the carbonicity map reproduce those previously argued to arise from contributions of the inner- and outer-halo populations, with peaks at [Fe/H] = −1.5 and −2.2, respectively. From consideration of the absolute carbon abundances for our sample, A (C), we also confirm that the carbon-enhanced metal-poor (CEMP) stars in the outer-halo region exhibit a higher frequency of CEMP-no stars (those with no overabundances of heavy neutron-capture elements) than of CEMP- s stars (those with strong overabundances of elements associated with the s -process), whereas the stars in the inner-halo region exhibit a higher frequency of CEMP- s stars. We argue that the contrast in the behavior of the CEMP-no and CEMP- s fractions in these regions arises from differences in the mass distributions of the mini-halos from which the stars of the inner- and outer-halo populations formed, which gives rise in turn to the observed dichotomy of the Galactic halo.

  5. An investigation of penetrant techniques for detection of machining-induced surface-breaking cracks on monolithic ceramics

    Energy Technology Data Exchange (ETDEWEB)

    Forster, G.A.; Ellingson, W.A.

    1996-02-01

    The purpose of this effort was to evaluate penetrant methods for their ability to detect surface-breaking cracks in monolithic ceramic materials with an emphasis on detection of cracks generated by machining. There are two basic penetrant types, visible and fluorescent. The visible penetrant method is usually augmented by powder developers and cracks detected can be seen in visible light. Cracks detected by fluorescent penetrant are visible only under ultraviolet light used with or without a developer. The developer is basically a powder that wicks up penetrant from a crack to make it more observable. Although fluorescent penetrants were recommended in the literature survey conducted early in this effort, visible penetrants and two non-standard techniques, a capillary gaseous diffusion method under development at the institute of Chemical Physics in Moscow, and the {open_quotes}statiflux{close_quotes} method which involves use of electrically charged particles, were also investigated. SiAlON ring specimens (1 in. diameter, 3/4 in. wide) which had been subjected to different thermal-shock cycles were used for these tests. The capillary gaseous diffusion method is based on ammonia; the detector is a specially impregnated paper much like litmus paper. As expected, visible dye penetrants offered no detection sensitivity for tight, surface-breaking cracks in ceramics. Although the non-standard statiflux method showed promise on high-crack-density specimens, it was ineffective on limited-crack-density specimens. The fluorescent penetrant method was superior for surface-breaking crack detection, but successful application of this procedure depends greatly on the skill of the user. Two presently available high-sensitivity fluorescent penetrants were then evaluated for detection of microcracks on Si{sub 3}N{sub 4} and SiC from different suppliers. Although 50X optical magnification may be sufficient for many applications, 200X magnification provides excellent delectability.

  6. Stellar halos: a rosetta stone for galaxy formation and cosmology

    Science.gov (United States)

    Inglis Read, Justin

    2015-08-01

    Stellar halos make up about a percent of the total stellar mass in galaxies. Yet their old age and long phase mixing times make them living fossil records of galactic history. In this talk, I review the latest simulations of structure formation in our standard Lambda Cold Dark Matter cosmology. I discuss the latest predictions for stellar halos and the relationship between the stellar halo light and the underlying dark matter. Finally, I discuss how these simulations compare to observations of the Milky Way and Andromeda and, ultimately, what this means for our cosmological model and the formation history of the Galaxy.

  7. Peripheral cholangiocarcinoma : Radiologic significance of hypoechoic halo sign on sonography

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Young Eok; Moon, Haeng Jin; Lee, Eun Ja; Ahn, In Oak [Gyeong Sang National Univ., College of Medicine, Chinju (Korea, Republic of)

    2001-12-01

    To determine the prevalence and characteristics of the hypoechoic halo sign in peripheral cholangiocarcinoma. Seventeen sonograms of 17 patients with peripheral cholangiocarcinoma histologically proven by either percutaneous needle biopsy (n=16) or surgical biopsy (n=1) were retrospectively reviewed. The size, margin, homogeneity and internal echogenicity of the masses as well as their peritumoral ductal dilatation and intratumoral calcification were ascertained, and the presence of a hypoechoic halo, and if present, its thickness and type, were also determined. We arbitrarily defined a 'thin' and 'thick' halo respectively, as one with a thickness less than of less than 3 mm, and 3 mm or more, and classified halos as 'intratumoral', 'extratumoral', or 'mixed'. Tumor diameter ranged from 4 to 13.5 (mean,7.3)cm, and the margin was well-defined in 15 cases (smooth: n=2; lobulated: n=13) and irregular in two. Echogenicity was slightly heterogeneous in 11 cases, severely heterogeneous in three, and hemogeneous in three, while the central portion was hyperechoic in eight cases, isoechoic in seven, and hypoechoic in only two. A hypoechoic halo was detected in 10 of 15 tumors (67%) with isoechoic centers. In evaluating the halo, two cases in which the mass was hypoechoic were excluded. All ten hypoechoic halos were at least 3 (range, 4-13; mean, 8.3) mm thick; in two cases the presence of a halo was equivocal, and in three there was no halo. Eight of ten halos were the mixed type, two were intratumoral, and none were extratumoral. Peritumoral ductal dilatation was seen in four cases (24%), but no internal calcification was observed. US showed that the margins of peripheral cholangiocarcinomas were mostly well-defined and smooth (12%) or lobulated (76%), and that masses were mainly heterogeneous (64%) A hypoechoic halo, which in all cases was thick and in 80% of cases was mixed, was noted in 67% of tumors with a hyper (47

  8. Evolution of Southern Hemisphere spring air masses observed by HALOE

    Science.gov (United States)

    Pierce, R. Bradley; Grose, William L.; Russell, James M., III; Tuck, Adrian F.

    1994-01-01

    The evolution of Southern Hemisphere air masses observed by the Halogen Occultation Experiment (HALOE) during September 21 through October 15, 1992, is investigated using isentropic trajectories computed from United Kingdom Meteorological Office (UKMO) assimilated winds and temperatures. Maps of constituent concentrations are obtained by accumulation of air masses from previous HALOE occultations. Lagged correlations between initial and subsequent HALOE observations of the same air mass are used to validate the air mass trajectories. High correlations are found for lag times as large as 10 days. Frequency distributions of the air mass constituent concentrations are used to examine constituent distributions in and around the Southern Hemisphere polar vortex.

  9. Connecting Galaxies, Halos, and Star Formation Rates Across Cosmic Time

    Energy Technology Data Exchange (ETDEWEB)

    Conroy, Charlie; Wechsler, Risa H.

    2008-06-02

    A simple, observationally-motivated model is presented for understanding how halo masses, galaxy stellar masses, and star formation rates are related, and how these relations evolve with time. The relation between halo mass and galaxy stellar mass is determined by matching the observed spatial abundance of galaxies to the expected spatial abundance of halos at multiple epochs--i.e. more massive galaxies are assigned to more massive halos at each epoch. This 'abundance matching' technique has been shown previously to reproduce the observed luminosity- and scale-dependence of galaxy clustering over a range of epochs. Halos at different epochs are connected by halo mass accretion histories estimated from N-body simulations. The halo-galaxy connection at fixed epochs in conjunction with the connection between halos across time provides a connection between observed galaxies across time. With approximations for the impact of merging and accretion on the growth of galaxies, one can then directly infer the star formation histories of galaxies as a function of stellar and halo mass. This model is tuned to match both the observed evolution of the stellar mass function and the normalization of the observed star formation rate--stellar mass relation to z {approx} 1. The data demands, for example, that the star formation rate density is dominated by galaxies with M{sub star} {approx} 10{sup 10.0-10.5} M{sub {circle_dot}} from 0 < z < 1, and that such galaxies over these epochs reside in halos with M{sub vir} {approx} 10{sup 11.5-12.5} M{sub {circle_dot}}. The star formation rate--halo mass relation is approximately Gaussian over the range 0 < z < 1 with a mildly evolving mean and normalization. This model is then used to shed light on a number of issues, including (1) a clarification of 'downsizing', (2) the lack of a sharp characteristic halo mass at which star formation is truncated, and (3) the dominance of star formation over merging to the stellar

  10. The immitigable nature of assembly bias: the impact of halo definition on assembly bias

    Science.gov (United States)

    Villarreal, Antonio S.; Zentner, Andrew R.; Mao, Yao-Yuan; Purcell, Chris W.; van den Bosch, Frank C.; Diemer, Benedikt; Lange, Johannes U.; Wang, Kuan; Campbell, Duncan

    2017-11-01

    Dark matter halo clustering depends not only on halo mass, but also on other properties such as concentration and shape. This phenomenon is known broadly as assembly bias. We explore the dependence of assembly bias on halo definition, parametrized by spherical overdensity parameter, Δ. We summarize the strength of concentration-, shape-, and spin-dependent halo clustering as a function of halo mass and halo definition. Concentration-dependent clustering depends strongly on mass at all Δ. For conventional halo definitions (Δ ˜ 200 - 600 m), concentration-dependent clustering at low mass is driven by a population of haloes that is altered through interactions with neighbouring haloes. Concentration-dependent clustering can be greatly reduced through a mass-dependent halo definition with Δ ˜ 20 - 40 m for haloes with M200 m ≲ 1012 h-1M⊙. Smaller Δ implies larger radii and mitigates assembly bias at low mass by subsuming altered, so-called backsplash haloes into now larger host haloes. At higher masses (M200 m ≳ 1013 h-1M⊙) larger overdensities, Δ ≳ 600 m, are necessary. Shape- and spin-dependent clustering are significant for all halo definitions that we explore and exhibit a relatively weaker mass dependence. Generally, both the strength and the sense of assembly bias depend on halo definition, varying significantly even among common definitions. We identify no halo definition that mitigates all manifestations of assembly bias. A halo definition that mitigates assembly bias based on one halo property (e.g. concentration) must be mass dependent. The halo definitions that best mitigate concentration-dependent halo clustering do not coincide with the expected average splashback radii at fixed halo mass.

  11. Fullerene Machines

    Science.gov (United States)

    Globus, Al; Saini, Subhash (Technical Monitor)

    1998-01-01

    Fullerenes possess remarkable properties and many investigators have examined the mechanical, electronic and other characteristics of carbon SP2 systems in some detail. In addition, C-60 can be functionalized with many classes of molecular fragments and we may expect the caps of carbon nanotubes to have a similar chemistry. Finally, carbon nanotubes have been attached to t he end of scanning probe microscope (Spill) tips. Spills can be manipulated with sub-angstrom accuracy. Together, these investigations suggest that complex molecular machines made of fullerenes may someday be created and manipulated with very high accuracy. We have studied some such systems computationally (primarily functionalized carbon nanotube gears and computer components). If such machines can be combined appropriately, a class of materials may be created that can sense their environment, calculate a response, and act. The implications of such hypothetical materials are substantial.

  12. Electric machines

    CERN Document Server

    Gross, Charles A

    2006-01-01

    BASIC ELECTROMAGNETIC CONCEPTSBasic Magnetic ConceptsMagnetically Linear Systems: Magnetic CircuitsVoltage, Current, and Magnetic Field InteractionsMagnetic Properties of MaterialsNonlinear Magnetic Circuit AnalysisPermanent MagnetsSuperconducting MagnetsThe Fundamental Translational EM MachineThe Fundamental Rotational EM MachineMultiwinding EM SystemsLeakage FluxThe Concept of Ratings in EM SystemsSummaryProblemsTRANSFORMERSThe Ideal n-Winding TransformerTransformer Ratings and Per-Unit ScalingThe Nonideal Three-Winding TransformerThe Nonideal Two-Winding TransformerTransformer Efficiency and Voltage RegulationPractical ConsiderationsThe AutotransformerOperation of Transformers in Three-Phase EnvironmentsSequence Circuit Models for Three-Phase Transformer AnalysisHarmonics in TransformersSummaryProblemsBASIC MECHANICAL CONSIDERATIONSSome General PerspectivesEfficiencyLoad Torque-Speed CharacteristicsMass Polar Moment of InertiaGearingOperating ModesTranslational SystemsA Comprehensive Example: The ElevatorP...

  13. Reconstruction of halo power spectrum from redshift-space galaxy distribution: cylinder-grouping method and halo exclusion effect

    Science.gov (United States)

    Okumura, Teppei; Takada, Masahiro; More, Surhud; Masaki, Shogo

    2017-07-01

    The peculiar velocity field measured by redshift-space distortions (RSD) in galaxy surveys provides a unique probe of the growth of large-scale structure. However, systematic effects arise when including satellite galaxies in the clustering analysis. Since satellite galaxies tend to reside in massive haloes with a greater halo bias, the inclusion boosts the clustering power. In addition, virial motions of the satellite galaxies cause a significant suppression of the clustering power due to non-linear RSD effects. We develop a novel method to recover the redshift-space power spectrum of haloes from the observed galaxy distribution by minimizing the contamination of satellite galaxies. The cylinder-grouping method (CGM) we study effectively excludes satellite galaxies from a galaxy sample. However, we find that this technique produces apparent anisotropies in the reconstructed halo distribution over all the scales which mimic RSD. On small scales, the apparent anisotropic clustering is caused by exclusion of haloes within the anisotropic cylinder used by the CGM. On large scales, the misidentification of different haloes in the large-scale structures, aligned along the line of sight, into the same CGM group causes the apparent anisotropic clustering via their cross-correlation with the CGM haloes. We construct an empirical model for the CGM halo power spectrum, which includes correction terms derived using the CGM window function at small scales as well as the linear matter power spectrum multiplied by a simple anisotropic function at large scales. We apply this model to a mock galaxy catalogue at z = 0.5, designed to resemble Sloan Digital Sky Survey-III Baryon Oscillation Spectroscopic Survey (BOSS) CMASS galaxies, and find that our model can predict both the monopole and quadrupole power spectra of the host haloes up to k < 0.5 {{h Mpc^{-1}}} to within 5 per cent.

  14. Genesis machines

    CERN Document Server

    Amos, Martyn

    2014-01-01

    Silicon chips are out. Today's scientists are using real, wet, squishy, living biology to build the next generation of computers. Cells, gels and DNA strands are the 'wetware' of the twenty-first century. Much smaller and more intelligent, these organic computers open up revolutionary possibilities. Tracing the history of computing and revealing a brave new world to come, Genesis Machines describes how this new technology will change the way we think not just about computers - but about life itself.

  15. Effect of a resonant excitation on the evolution of the beam emittance and halo population

    CERN Document Server

    Fitterer, Miriam; Valishev, Alexander; Bruce, Roderik; Redaelli, Stefano; Salvachua Ferrando, Belen Maria; Valuch, Daniel; Valentino, Gianluca; Wagner, Joschka; CERN. Geneva. ATS Department

    2018-01-01

    Collimation with hollow electron beams or lenses (HEL) is currently one of the most promising concepts for active halo control in HL-LHC. In previous studies it has been shown that the halo can be efficiently removed with a hollow electron lens. Equally important as an efficient removal of the halo, is to demonstrate that the core stays unperturbed. In the case of an ideal hollow electron lens without bends, the field at the location of the beam core vanishes and the core thus remains unperturbed. In reality, the field at the beam core does not vanish entirely due to imperfections in the electron beam profile and the electron lens bends necessary to guide the electron in and out of the proton aperture. In particular, in the case of a pulsed operation of the electron lens the non-vanishing residual field induces noise on the proton beam. To identify the most sensitive pulsing patterns for the resonant mode and derive tolerances on the profile imperfections, a first MD (MD1415) was carried out on 24.08.2016 [1]...

  16. Effect of a resonant excitation on the evolution of the beam emittance and halo population

    CERN Document Server

    Fitterer, Miriam; Valishev, Alexander; Bruce, Roderik; Papadopoulou, Parthena Stefania; Papotti, Giulia; Pellegrini, Dario; Redaelli, Stefano; Trad, Georges; Valuch, Daniel; Valentino, Gianluca; Wagner, Joschka; Xu, Chen; CERN. Geneva. ATS Department

    2017-01-01

    Collimation with hollow electron beams or lenses (HEL) is currently one of the most promising concepts for active halo control in HL-LHC. In previous studies it has been shown that the halo can be efficiently removed with a hollow electron lens. Equally important as an efficient removal of the halo, is to demonstrate that the core stays unperturbed. In the case of an ideal hollow electron lens without bends, the field at the location of the beam core vanishes and the core remains unperturbed. In reality, the field at the beam core does not vanish entirely due to imperfections in the electron beam profile and the electron lens bends necessary to guide the electron in and out of the proton aperture. In particular, in the case of a pulsed operation of the electron lens the non-vanishing residual field induces noise on the proton beam. To identify the most sensitive pulsing patterns for the resonant mode and derive tolerances on the profile imperfections, a first MD was carried out of which the first results...

  17. Ultra Light Axionic Dark Matter: Galactic Halos and Implications for Observations with Pulsar Timing Arrays

    Directory of Open Access Journals (Sweden)

    Ivan de Martino

    2018-01-01

    Full Text Available The cold dark matter (CDM paradigm successfully explains the cosmic structure over an enormous span of redshifts. However, it fails when probing the innermost regions of dark matter halos and the properties of the Milky Way’s dwarf galaxy satellites. Moreover, the lack of experimental detection of Weakly Interacting Massive Particle (WIMP favors alternative candidates such as light axionic dark matter that naturally arise in string theory. Cosmological N-body simulations have shown that axionic dark matter forms a solitonic core of size of ≃150 pc in the innermost region of the galactic halos. The oscillating scalar field associated to the axionic dark matter halo produces an oscillating gravitational potential that induces a time dilation of the pulse arrival time of ≃400 ns/(m B /10 − 22 eV for pulsar within such a solitonic core. Over the whole galaxy, the averaged predicted signal may be detectable with current and forthcoming pulsar timing array telescopes.

  18. Artificial Molecular Machines.

    Science.gov (United States)

    Balzani; Credi; Raymo; Stoddart

    2000-10-02

    of molecular machines by focusing on past achievements, present limitations, and future perspectives. After analyzing a few important examples of natural molecular machines, the most significant developments in the field of artificial molecular machines are highlighted. The systems reviewed include 1) chemical rotors, 2) photochemically and electrochemically induced molecular (conformational) rearrangements, and 3) chemically, photochemically, and electrochemically controllable (co-conformational) motions in interlocked molecules (catenanes and rotaxanes), as well as in coordination and supramolecular complexes, including pseudorotaxanes. Artificial molecular machines based on biomolecules and interfacing artificial molecular machines with surfaces and solid supports are amongst some of the cutting-edge topics featured in this review. The extension of the concept of a machine to the molecular level is of interest not only for the sake of basic research, but also for the growth of nanoscience and the subsequent development of nanotechnology.

  19. A study of electrodischarge machining–pulse electrochemical machining combined machining for holes with high surface quality on superalloy

    Directory of Open Access Journals (Sweden)

    Ning Ma

    2015-11-01

    Full Text Available Noncircular holes on the surface of turbine rotor blades are usually machined by electrodischarge machining. A recast layer containing numerous micropores and microcracks is easily generated during the electrodischarge machining process due to the rapid heating and cooling effects, which restrict the wide applications of noncircular holes in aerospace and aircraft industries. Owing to the outstanding advantages of pulse electrochemical machining, electrodischarge machining–pulse electrochemical machining combined technique is provided to improve the overall quality of electrodischarge machining-drilled holes. The influence of pulse electrochemical machining processing parameters on the surface roughness and the influence of the electrodischarge machining–pulse electrochemical machining method on the surface quality and accuracy of holes have been studied experimentally. The results indicate that the pulse electrochemical machining processing time for complete removal of the recast layer decreases with the increase in the pulse electrochemical machining current. The low pulse electrochemical machining current results in uneven dissolution of the recast layer, while the higher pulse electrochemical machining current induces relatively homogeneous dissolution. The surface roughness is reduced from 4.277 to 0.299 µm, and the hole taper induced by top-down electrodischarge machining process was reduced from 1.04° to 0.17° after pulse electrochemical machining. On account of the advantages of electrodischarge machining and the pulse electrochemical machining, the electrodischarge machining–pulse electrochemical machining combined technique could be applied for machining noncircular holes with high shape accuracy and surface quality.

  20. On the galaxy-halo connection in the EAGLE simulation

    Science.gov (United States)

    Desmond, Harry; Mao, Yao-Yuan; Wechsler, Risa H.; Crain, Robert A.; Schaye, Joop

    2017-10-01

    Empirical models of galaxy formation require assumptions about the correlations between galaxy and halo properties. These may be calibrated against observations or inferred from physical models such as hydrodynamical simulations. In this Letter, we use the EAGLE simulation to investigate the correlation of galaxy size with halo properties. We motivate this analysis by noting that the common assumption of angular momentum partition between baryons and dark matter in rotationally supported galaxies overpredicts both the spread in the stellar mass-size relation and the anticorrelation of size and velocity residuals, indicating a problem with the galaxy-halo connection it implies. We find the EAGLE galaxy population to perform significantly better on both statistics, and trace this success to the weakness of the correlations of galaxy size with halo mass, concentration and spin at fixed stellar mass. Using these correlations in empirical models will enable fine-grained aspects of galaxy scalings to be matched.

  1. Visibility of stars, halos, and rainbows during solar eclipses.

    Science.gov (United States)

    Können, Gunther P; Hinz, Claudia

    2008-12-01

    The visibility of stars, planets, diffraction coronas, halos, and rainbows during the partial and total phases of a solar eclipse is studied. The limiting magnitude during various stages of the partial phase is presented. The sky radiance during totality with respect to noneclipse conditions is revisited and found to be typically 1/4000. The corresponding limiting magnitude is +3.5. At totality, the signal-to-background ratio of diffraction coronas, halos, and rainbows has dropped by a factor of 250. It is found that diffraction coronas around the totally eclipsed Sun may nevertheless occur. Analyses of lunar halo observations during twilight indicate that bright halo displays may also persist during totality. Rainbows during totality seem impossible.

  2. Planetary nebulae as kinematic tracers of galaxy stellar halos

    Science.gov (United States)

    Coccato, Lodovico

    2017-10-01

    The kinematic and dynamical properties of galaxy stellar halos are difficult to measure because of the faint surface brightness that characterizes these regions. Spiral galaxies can be probed using the radio Hi emission; on the contrary, early-type galaxies contain less gas, therefore alternative kinematic tracers need to be used. Planetary nebulae (PNe) can be easily detected far out in the halo thanks to their bright emission lines. It is therefore possible to map the halo kinematics also in early-type galaxies, typically out to 5 effective radii or beyond. Thanks to the recent spectroscopic surveys targeting extra-galactic PNe, we can now rely on a few tens of galaxies where the kinematics of the stellar halos are measured. Here, I will review the main results obtained in this field in the last decades.

  3. Halo performance on low light level image intensifiers

    Science.gov (United States)

    Cui, Dongxu; Ren, Ling; Chang, Benkang; Shi, Feng; Shi, Jifang; Qian, Yunsheng; Wang, Honggang; Zhang, Junju

    To analyze the formation mechanism of the halo on low light level image intensifiers and the influencing factors on the halo size, a halo tester has been designed. Under the illumination between 10-2 lx and 10-4 lx, we use the tester to collect a 0.1922 mm hole image directly with CoolSNAPK4 charge-coupled device (CCD) in a darkroom. The practical measurement result shows that the amplification ratio is 343.4. Then we put the super second and third generation image intensifiers after the hole, and the halo sizes of the hole images on the screens are determined as 0.2388 and 0.5533 mm respectively. The results are helpful to improve the quality of the low light level image intensifiers.

  4. Summary of the 2014 Beam-Halo Monitoring Workshop

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, Alan

    2015-09-25

    Understanding and controlling beam halo is important for high-intensity hadron accelerators, for high-brightness electron linacs, and for low-emittance light sources. This can only be achieved by developing suitable diagnostics. The main challenge faced by such instrumentation is the high dynamic range needed to observe the halo in the presence of an intense core. In addition, measurements must often be made non-invasively. This talk summarizes the one-day workshop on Beam-Halo Monitoring that was held at SLAC on September 19 last year, immediately following IBIC 2014 in Monterey. Workshop presentations described invasive techniques using wires, screens, or crystal collimators, and non-invasive measurements with gas or scattered electrons. Talks on optical methods showed the close links between observing halo and astronomical problems like observing the solar corona or directly observing a planet orbiting another star.

  5. UARS Halogen Occultation Experiment (HALOE) Level 3AT V001

    Data.gov (United States)

    National Aeronautics and Space Administration — The Halogen Occultation Experiment (HALOE) Level 3AT data product consists of daily vertical profiles of temperature, aerosol extinction and concentrations of HCl,...

  6. Revisiting Scaling Relations for Giant Radio Halos in Galaxy Clusters

    Science.gov (United States)

    Cassano, R.; Ettori, S.; Brunetti, G.; Giacintucci, S.; Pratt, G. W.; Venturi, T.; Kale, R.; Dolag, K.; Markevitch, Maxim L.

    2013-01-01

    Many galaxy clusters host megaparsec-scale radio halos, generated by ultrarelativistic electrons in the magnetized intracluster medium. Correlations between the synchrotron power of radio halos and the thermal properties of the hosting clusters were established in the last decade, including the connection between the presence of a halo and cluster mergers. The X-ray luminosity and redshift-limited Extended GMRT Radio Halo Survey provides a rich and unique dataset for statistical studies of the halos. We uniformly analyze the radio and X-ray data for the GMRT cluster sample, and use the new Planck Sunyaev-Zel'dovich (SZ) catalog to revisit the correlations between the power of radio halos and the thermal properties of galaxy clusters. We find that the radio power at 1.4 GHz scales with the cluster X-ray (0.1-2.4 keV) luminosity computed within R(sub 500) as P(sub 1.4) approx. L(2.1+/-0.2) - 500). Our bigger and more homogenous sample confirms that the X-ray luminous (L(sub 500) > 5 × 10(exp 44) erg/s)) clusters branch into two populations-radio halos lie on the correlation, while clusters without radio halos have their radio upper limits well below that correlation. This bimodality remains if we excise cool cores from the X-ray luminosities. We also find that P(sub 1.4) scales with the cluster integrated SZ signal within R(sub 500), measured by Planck, as P(sub 1.4) approx. Y(2.05+/-0.28) - 500), in line with previous findings. However, contrary to previous studies that were limited by incompleteness and small sample size, we find that "SZ-luminous" Y(sub 500) > 6×10(exp -5) Mpc(exp 2) clusters show a bimodal behavior for the presence of radio halos, similar to that in the radio-X-ray diagram. Bimodality of both correlations can be traced to clusters dynamics, with radio halos found exclusively in merging clusters. These results confirm the key role of mergers for the origin of giant radio halos, suggesting that they trigger the relativistic particle acceleration.

  7. Testing approximate predictions of displacements of cosmological dark matter halos

    Science.gov (United States)

    Munari, Emiliano; Monaco, Pierluigi; Koda, Jun; Kitaura, Francisco-Shu; Sefusatti, Emiliano; Borgani, Stefano

    2017-07-01

    We present a test to quantify how well some approximate methods, designed to reproduce the mildly non-linear evolution of perturbations, are able to reproduce the clustering of DM halos once the grouping of particles into halos is defined and kept fixed. The following methods have been considered: Lagrangian Perturbation Theory (LPT) up to third order, Truncated LPT, Augmented LPT, MUSCLE and COLA. The test runs as follows: halos are defined by applying a friends-of-friends (FoF) halo finder to the output of an N-body simulation. The approximate methods are then applied to the same initial conditions of the simulation, producing for all particles displacements from their starting position and velocities. The position and velocity of each halo are computed by averaging over the particles that belong to that halo, according to the FoF halo finder. This procedure allows us to perform a well-posed test of how clustering of the matter density and halo density fields are recovered, without asking to the approximate method an accurate reconstruction of halos. We have considered the results at z=0,0.5,1, and we have analysed power spectrum in real and redshift space, object-by-object difference in position and velocity, density Probability Distribution Function (PDF) and its moments, phase difference of Fourier modes. We find that higher LPT orders are generally able to better reproduce the clustering of halos, while little or no improvement is found for the matter density field when going to 2LPT and 3LPT. Augmentation provides some improvement when coupled with 2LPT, while its effect is limited when coupled with 3LPT. Little improvement is brought by MUSCLE with respect to Augmentation. The more expensive particle-mesh code COLA outperforms all LPT methods, and this is true even for mesh sizes as large as the inter-particle distance. This test sets an upper limit on the ability of these methods to reproduce the clustering of halos, for the cases when these objects are

  8. A study of machine learning regression methods for major elemental analysis of rocks using laser-induced breakdown spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Boucher, Thomas F., E-mail: boucher@cs.umass.edu [School of Computer Science, University of Massachusetts Amherst, 140 Governor' s Drive, Amherst, MA 01003, United States. (United States); Ozanne, Marie V. [Department of Astronomy, Mount Holyoke College, South Hadley, MA 01075 (United States); Carmosino, Marco L. [School of Computer Science, University of Massachusetts Amherst, 140 Governor' s Drive, Amherst, MA 01003, United States. (United States); Dyar, M. Darby [Department of Astronomy, Mount Holyoke College, South Hadley, MA 01075 (United States); Mahadevan, Sridhar [School of Computer Science, University of Massachusetts Amherst, 140 Governor' s Drive, Amherst, MA 01003, United States. (United States); Breves, Elly A.; Lepore, Kate H. [Department of Astronomy, Mount Holyoke College, South Hadley, MA 01075 (United States); Clegg, Samuel M. [Los Alamos National Laboratory, P.O. Box 1663, MS J565, Los Alamos, NM 87545 (United States)

    2015-05-01

    dimensionality of the data (6144 channels) relative to the small number of samples studied. The best-performing models were SVR-Lin for SiO{sub 2}, MgO, Fe{sub 2}O{sub 3}, and Na{sub 2}O, lasso for Al{sub 2}O{sub 3}, elastic net for MnO, and PLS-1 for CaO, TiO{sub 2}, and K{sub 2}O. Although these differences in model performance between methods were identified, most of the models produce comparable results when p ≤ 0.05 and all techniques except kNN produced statistically-indistinguishable results. It is likely that a combination of models could be used together to yield a lower total error of prediction, depending on the requirements of the user. - Highlights: • We compared 9 machine learning regression models for predicting mineral composition from LIBS. • These models vary over factors: linear/nonlinear, sparse/dense, univariate/multivariate. • The linear models evaluated generalized well for out-of-sample predictions. • The nonlinear models evaluated tended to overfit the training data and generalize poorly. • Sparse models best predicted the elements with a small number of high transition probability emission lines.

  9. Vaporization in comets - The icy grain halo of Comet West

    Science.gov (United States)

    Ahearn, M. F.; Cowan, J. J.

    1980-01-01

    The variation with heliocentric distance of the production rates of various species in Comet West (1975n = 1976 VI) is explained with a cometary model consisting of a CO2 dominated nucleus plus a halo of icy grains of H2O or clathrate hydrate. It is concluded that the parents of CN and C3 are released primarily from the nucleus but that the parent of C2 is released primarily from the halo of icy grains.

  10. Integrated Marketing Communications (IMC) Di PT Halo Rumah Bernyanyi

    OpenAIRE

    Rismayanti, Rebekka

    2016-01-01

    : This research aims to describe the effectiveness of Integrated Marketing Communication (IMC) in PT Halo Rumah Bernyanyi which, from the perspective of marketing strategy, could be studied by analyzing the segmentation, targeting, and positioning. Using case-study method with in-depth interview, the result shows that the implementation of IMC at PT Halo Rumah Bernyayi is arranged in one single strategy and tend to neglect the complexities of running multi-brand family karaoke-house. This con...

  11. Integrated Marketing Communications (IMC) di PT Halo Rumah Bernyanyi

    OpenAIRE

    Rebekka Rismayanti

    2017-01-01

    Abstract: This research aims to describe the effectiveness of Integrated Marketing Communication (IMC) in PT Halo Rumah Bernyanyi which, from the perspective of marketing strategy, could be studied by analyzing the segmentation, targeting, and positioning. Using case-study method with in-depth interview, the result shows that the implementation of IMC at PT Halo Rumah Bernyayi is arranged in one single strategy and tend to neglect the complexities of running multi-brand family karaoke-house. ...

  12. Non-Gaussianity and Excursion Set Theory: Halo Bias

    Energy Technology Data Exchange (ETDEWEB)

    Adshead, Peter [Enrico Fermi Institute, Univ. of Chicago, IL (United States); Baxter, Eric J. [Univ. of Chicago, Chicago, IL (United States); Dodelson, Scott [Fermi National Accelerator Laboratory (FNAL), Batavia, IL (United States); Lidz, Adam [Univ. of Pennsylvania, Philadelphia, PA (United States)

    2012-09-01

    We study the impact of primordial non-Gaussianity generated during inflation on the bias of halos using excursion set theory. We recapture the familiar result that the bias scales as $k^{-2}$ on large scales for local type non-Gaussianity but explicitly identify the approximations that go into this conclusion and the corrections to it. We solve the more complicated problem of non-spherical halos, for which the collapse threshold is scale dependent.

  13. Nano-mechanics of HaloTag Tethers

    OpenAIRE

    Popa, Ionel; Berkovich, Ronen; Alegre-Cebollada, Jorge; Badilla, Carmen L.; Rivas-Pardo, Jaime Andres; Taniguchi, Yukinori; Kawakami, Masaru; Fernandez, Julio M.

    2013-01-01

    The active site of the Haloalkane Dehydrogenase (HaloTag) enzyme can be covalently attached to a chloroalkane ligand providing a mechanically strong tether, resistant to large pulling forces. Here we demonstrate the covalent tethering of protein L and I27 polyproteins between an AFM cantilever and a glass surface using HaloTag anchoring at one end, and thiol chemistry at the other end. Covalent tethering is unambiguously confirmed by the observation of full length polyprotein unfolding, combi...

  14. Two Stellar Components in the Halo of the Milky Way

    Science.gov (United States)

    2007-12-13

    distributed throughout the primordial interstellar medium by stellar winds and supernovae . Previous work has provided evidence that the halo of the Milky...the number of stars), for samples in which a counter-rotating halo has been claimed, ordered by sample size. The samples listed in the first column...sample by the authors are listed in the third column (see original papers for details). The method of analysis used for each determination is listed : F&W

  15. The globular cluster-dark matter halo connection

    Science.gov (United States)

    Boylan-Kolchin, Michael

    2017-12-01

    I present a simple phenomenological model for the observed linear scaling of the stellar mass in old globular clusters (GCs) with $z=0$ halo mass in which the stellar mass in GCs scales linearly with progenitor halo mass at $z=6$ above a minimum halo mass for GC formation. This model reproduces the observed $M_{\\rm GCs}-M_{\\rm halo}$ relation at $z=0$ and results in a prediction for the minimum halo mass at $z=6$ required for hosting one GC: $M_{\\rm min}(z=6)=1.07 \\times 10^9\\,M_{\\odot}$. Translated to $z=0$, the mean threshold mass is $M_{\\rm halo}(z=0) \\approx 2\\times 10^{10}\\,M_{\\odot}$. I explore the observability of GCs in the reionization era and their contribution to cosmic reionization, both of which depend sensitively on the (unknown) ratio of GC birth mass to present-day stellar mass, $\\xi$. Based on current detections of $z \\gtrsim 6$ objects with $M_{1500} 10$ are strongly disfavored; this, in turn, has potentially important implications for GC formation scenarios. Even for low values of $\\xi$, some observed high-$z$ galaxies may actually be GCs, complicating estimates of reionization-era galaxy ultraviolet luminosity functions and constraints on dark matter models. GCs are likely important reionization sources if $5 \\lesssim \\xi \\lesssim 10$. I also explore predictions for the fraction of accreted versus in situ GCs in the local Universe and for descendants of systems at the halo mass threshold of GC formation (dwarf galaxies). An appealing feature of the model presented here is the ability to make predictions for GC properties based solely on dark matter halo merger trees.

  16. Stellar-to-halo mass relation of cluster galaxies

    Science.gov (United States)

    Niemiec, Anna; Jullo, Eric; Limousin, Marceau; Giocoli, Carlo; Erben, Thomas; Hildebrant, Hendrik; Kneib, Jean-Paul; Leauthaud, Alexie; Makler, Martin; Moraes, Bruno; Pereira, Maria E. S.; Shan, Huanyuan; Rozo, Eduardo; Rykoff, Eli; Van Waerbeke, Ludovic

    2017-10-01

    In the formation of galaxy groups and clusters, the dark matter haloes containing satellite galaxies are expected to be tidally stripped in gravitational interactions with the host. We use galaxy-galaxy weak lensing to measure the average mass of dark matter haloes of satellite galaxies as a function of projected distance to the centre of the host, since stripping is expected to be greater for satellites closer to the centre of the cluster. We further classify the satellites according to their stellar mass: Assuming that the stellar component of the galaxy is less disrupted by tidal stripping, stellar mass can be used as a proxy of the infall mass. We study the stellar-to-halo mass relation of satellites as a function of the cluster-centric distance to measure tidal stripping. We use the shear catalogues of the Dark Energy Survey (DES) science verification archive, the Canada-France-Hawaii Lensing Survey (CFHTLenS) and the CFHT Stripe 82 surveys, and we select satellites from the redMaPPer catalogue of clusters. For galaxies located in the outskirts of clusters, we find a stellar-to- halo mass relation in good agreement with the theoretical expectations from Moster et al. for central galaxies. In the centre of the cluster, we find that this relation is shifted to smaller halo mass for a given stellar mass. We interpret this finding as further evidence for tidal stripping of dark matter haloes in high-density environments.

  17. Nano-mechanics of HaloTag Tethers

    Science.gov (United States)

    Popa, Ionel; Berkovich, Ronen; Alegre-Cebollada, Jorge; Badilla, Carmen L.; Rivas-Pardo, Jaime Andres; Taniguchi, Yukinori; Kawakami, Masaru; Fernandez, Julio M.

    2013-01-01

    The active site of the Haloalkane Dehydrogenase (HaloTag) enzyme can be covalently attached to a chloroalkane ligand providing a mechanically strong tether, resistant to large pulling forces. Here we demonstrate the covalent tethering of protein L and I27 polyproteins between an AFM cantilever and a glass surface using HaloTag anchoring at one end, and thiol chemistry at the other end. Covalent tethering is unambiguously confirmed by the observation of full length polyprotein unfolding, combined with high detachment forces that range up to ~2000 pN. We use these covalently anchored polyproteins to study the remarkable mechanical properties of HaloTag proteins. We show that the force that triggers unfolding of the HaloTag protein exhibits a four-fold increase, from 131 pN to 491 pN, when the direction of the applied force is changed from the C-terminus to the N-terminus. Force-clamp experiments reveal that unfolding of the HaloTag protein is twice more sensitive to pulling force compared to protein L, and refolds at a slower rate. We show how these properties allow for the long-term observation of protein folding-unfolding cycles at high forces, without interference from the HaloTag tether. PMID:23909704

  18. What to expect from dynamical modelling of galactic haloes

    Science.gov (United States)

    Wang, Wenting; Han, Jiaxin; Cole, Shaun; Frenk, Carlos; Sawala, Till

    2017-09-01

    Many dynamical models of the Milky Way halo require assumptions that the distribution function of a tracer population should be independent of time (I.e. a steady-state distribution function) and that the underlying potential is spherical. We study the limitations of such modelling by applying a general dynamical model with minimal assumptions to a large sample of galactic haloes from cosmological N-body and hydrodynamical simulations. Using dark matter particles as dynamical tracers, we find that the systematic uncertainties in the measured mass and concentration parameters typically have an amplitude of 25-40 per cent. When stars are used as tracers, however, the systematic uncertainties can be as large as a factor of 2-3. The systematic uncertainties are not reduced by increasing the tracer sample size and vary stochastically from halo to halo. These systematic uncertainties are mostly driven by underestimated statistical noise caused by correlated phase-space structures that violate the steady-state assumption. The number of independent phase-space structures inferred from the uncertainty level sets a limiting sample size beyond which a further increase no longer significantly improves the accuracy of dynamical inferences. The systematic uncertainty level is determined by the halo merger history, the shape and environment of the halo. Our conclusions apply generally to any spherical steady-state model.

  19. Cold dark matter. 1: The formation of dark halos

    Science.gov (United States)

    Gelb, James M.; Bertschinger, Edmund

    1994-01-01

    We use numerical simulations of critically closed cold dark matter (CDM) models to study the effects of numerical resolution on observable quantities. We study simulations with up to 256(exp 3) particles using the particle-mesh (PM) method and with up to 144(exp 3) particles using the adaptive particle-particle-mesh (P3M) method. Comparisons of galaxy halo distributions are made among the various simulations. We also compare distributions with observations, and we explore methods for identifying halos, including a new algorithm that finds all particles within closed contours of the smoothed density field surrounding a peak. The simulated halos show more substructure than predicted by the Press-Schechter theory. We are able to rule out all omega = 1 CDM models for linear amplitude sigma(sub 8) greater than or approximately = 0.5 because the simulations produce too many massive halos compared with the observations. The simulations also produce too many low-mass halos. The distribution of halos characterized by their circular velocities for the P3M simulations is in reasonable agreement with the observations for 150 km/s less than or = V(sub circ) less than or = 350 km/s.

  20. Simulating Turing machines on Maurer machines

    NARCIS (Netherlands)

    Bergstra, J.A.; Middelburg, C.A.

    2008-01-01

    In a previous paper, we used Maurer machines to model and analyse micro-architectures. In the current paper, we investigate the connections between Turing machines and Maurer machines with the purpose to gain an insight into computability issues relating to Maurer machines. We introduce ways to

  1. Beam halo collimation in heavy ion synchrotrons

    Directory of Open Access Journals (Sweden)

    I. Strašík

    2015-08-01

    Full Text Available This paper presents a systematic study of the halo collimation of ion beams from proton up to uranium in synchrotrons. The projected Facility for Antiproton and Ion Research synchrotron SIS100 is used as a reference case. The concepts are separated into fully stripped (e.g., ^{238}U^{92+} and partially stripped (e.g., ^{238}U^{28+} ion collimation. An application of the two-stage betatron collimation system, well established for proton accelerators, is intended also for fully stripped ions. The two-stage system consists of a primary collimator (a scattering foil and secondary collimators (bulky absorbers. Interaction of the particles with the primary collimator (scattering, momentum losses, and nuclear interactions was simulated by using fluka. Particle-tracking simulations were performed by using mad-x. Finally, the dependence of the collimation efficiency on the primary ion species was determined. The influence of the collimation system adjustment, lattice imperfections, and beam parameters was estimated. The concept for the collimation of partially stripped ions employs a thin stripping foil in order to change their charge state. These ions are subsequently deflected towards a dump location using a beam optical element. The charge state distribution after the stripping foil was obtained from global. The ions were tracked by using mad–x.

  2. Environmentally Friendly Machining

    CERN Document Server

    Dixit, U S; Davim, J Paulo

    2012-01-01

    Environment-Friendly Machining provides an in-depth overview of environmentally-friendly machining processes, covering numerous different types of machining in order to identify which practice is the most environmentally sustainable. The book discusses three systems at length: machining with minimal cutting fluid, air-cooled machining and dry machining. Also covered is a way to conserve energy during machining processes, along with useful data and detailed descriptions for developing and utilizing the most efficient modern machining tools. Researchers and engineers looking for sustainable machining solutions will find Environment-Friendly Machining to be a useful volume.

  3. Machine capability index evaluation of machining center

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Won Pyo [Korea Institute of Industrial Technology, Ansan (Korea, Republic of)

    2013-10-15

    Recently, there has been an increasing need to produce more precise products, with only the smallest deviations from a defined target value. Machine capability is the ability of a machine tool to produce parts within the tolerance interval. Capability indices are a statistical way of describing how well a product is machined compared to defined target values and tolerances. Currently, there is no standardized way to acquire a machine capability value. This paper describes how machine capability indices are evaluated in machining centers. After the machining of specimens, straightness, roundness and positioning accuracy were measured using CMM(coordinate measuring machine). These measured values and defined tolerances were used to evaluate the machine capability index. It will be useful for the industry to have standardized ways to choose and calculate machine capability indices.

  4. Long-Term Training with a Brain-Machine Interface-Based Gait Protocol Induces Partial Neurological Recovery in Paraplegic Patients.

    Science.gov (United States)

    Donati, Ana R C; Shokur, Solaiman; Morya, Edgard; Campos, Debora S F; Moioli, Renan C; Gitti, Claudia M; Augusto, Patricia B; Tripodi, Sandra; Pires, Cristhiane G; Pereira, Gislaine A; Brasil, Fabricio L; Gallo, Simone; Lin, Anthony A; Takigami, Angelo K; Aratanha, Maria A; Joshi, Sanjay; Bleuler, Hannes; Cheng, Gordon; Rudolph, Alan; Nicolelis, Miguel A L

    2016-08-11

    Brain-machine interfaces (BMIs) provide a new assistive strategy aimed at restoring mobility in severely paralyzed patients. Yet, no study in animals or in human subjects has indicated that long-term BMI training could induce any type of clinical recovery. Eight chronic (3-13 years) spinal cord injury (SCI) paraplegics were subjected to long-term training (12 months) with a multi-stage BMI-based gait neurorehabilitation paradigm aimed at restoring locomotion. This paradigm combined intense immersive virtual reality training, enriched visual-tactile feedback, and walking with two EEG-controlled robotic actuators, including a custom-designed lower limb exoskeleton capable of delivering tactile feedback to subjects. Following 12 months of training with this paradigm, all eight patients experienced neurological improvements in somatic sensation (pain localization, fine/crude touch, and proprioceptive sensing) in multiple dermatomes. Patients also regained voluntary motor control in key muscles below the SCI level, as measured by EMGs, resulting in marked improvement in their walking index. As a result, 50% of these patients were upgraded to an incomplete paraplegia classification. Neurological recovery was paralleled by the reemergence of lower limb motor imagery at cortical level. We hypothesize that this unprecedented neurological recovery results from both cortical and spinal cord plasticity triggered by long-term BMI usage.

  5. Long-Term Training with a Brain-Machine Interface-Based Gait Protocol Induces Partial Neurological Recovery in Paraplegic Patients

    Science.gov (United States)

    Donati, Ana R. C.; Shokur, Solaiman; Morya, Edgard; Campos, Debora S. F.; Moioli, Renan C.; Gitti, Claudia M.; Augusto, Patricia B.; Tripodi, Sandra; Pires, Cristhiane G.; Pereira, Gislaine A.; Brasil, Fabricio L.; Gallo, Simone; Lin, Anthony A.; Takigami, Angelo K.; Aratanha, Maria A.; Joshi, Sanjay; Bleuler, Hannes; Cheng, Gordon; Rudolph, Alan; Nicolelis, Miguel A. L.

    2016-01-01

    Brain-machine interfaces (BMIs) provide a new assistive strategy aimed at restoring mobility in severely paralyzed patients. Yet, no study in animals or in human subjects has indicated that long-term BMI training could induce any type of clinical recovery. Eight chronic (3–13 years) spinal cord injury (SCI) paraplegics were subjected to long-term training (12 months) with a multi-stage BMI-based gait neurorehabilitation paradigm aimed at restoring locomotion. This paradigm combined intense immersive virtual reality training, enriched visual-tactile feedback, and walking with two EEG-controlled robotic actuators, including a custom-designed lower limb exoskeleton capable of delivering tactile feedback to subjects. Following 12 months of training with this paradigm, all eight patients experienced neurological improvements in somatic sensation (pain localization, fine/crude touch, and proprioceptive sensing) in multiple dermatomes. Patients also regained voluntary motor control in key muscles below the SCI level, as measured by EMGs, resulting in marked improvement in their walking index. As a result, 50% of these patients were upgraded to an incomplete paraplegia classification. Neurological recovery was paralleled by the reemergence of lower limb motor imagery at cortical level. We hypothesize that this unprecedented neurological recovery results from both cortical and spinal cord plasticity triggered by long-term BMI usage. PMID:27513629

  6. Introduction to Machine Protection

    CERN Document Server

    Schmidt, R

    2016-01-01

    Protection of accelerator equipment is as old as accelerator technology and was for many years related to high-power equipment. Examples are the protection of powering equipment from overheating (magnets, power converters, high-current cables), of superconducting magnets from damage after a quench and of klystrons. The protection of equipment from beam accidents is more recent, although there was one paper that discussed beam-induced damage for the SLAC linac (Stanford Linear Accelerator Center) as early as in 1967. It is related to the increasing beam power of high-power proton accelerators, to the emission of synchrotron light by electron-positron accelerators and to the increase of energy stored in the beam. Designing a machine protection system requires an excellent understanding of accelerator physics and operation to anticipate possible failures that could lead to damage. Machine protection includes beam and equipment monitoring, a system to safely stop beam operation (e.g. dumping the beam or stopping ...

  7. Machine Protection

    CERN Document Server

    Schmidt, R

    2014-01-01

    The protection of accelerator equipment is as old as accelerator technology and was for many years related to high-power equipment. Examples are the protection of powering equipment from overheating (magnets, power converters, high-current cables), of superconducting magnets from damage after a quench and of klystrons. The protection of equipment from beam accidents is more recent. It is related to the increasing beam power of high-power proton accelerators such as ISIS, SNS, ESS and the PSI cyclotron, to the emission of synchrotron light by electron–positron accelerators and FELs, and to the increase of energy stored in the beam (in particular for hadron colliders such as LHC). Designing a machine protection system requires an excellent understanding of accelerator physics and operation to anticipate possible failures that could lead to damage. Machine protection includes beam and equipment monitoring, a system to safely stop beam operation (e.g. dumping the beam or stopping the beam at low energy) and an ...

  8. Machine consciousness.

    Science.gov (United States)

    Aleksander, Igor

    2005-01-01

    The work from several laboratories on the modeling of consciousness is reviewed. This ranges, on one hand, from purely functional models where behavior is important and leads to an attribution of consciousness to, on the other hand, material work closely derived from the information about the anatomy of the brain. At the functional end of the spectrum, applications are described specifically directed at a job-finding problem, where the person being served should not discern between being served by a conscious human or a machine. This employs an implementation of global workspace theories. At the material end, attempts at modeling attentional brain mechanisms, and basic biochemical processes in children are discussed. There are also general prescriptions for functional schemas that facilitate discussions for the presence of consciousness in computational systems and axiomatic structures that define necessary architectural features without which it would be difficult to represent sensations. Another distinction between these two approaches is whether one attempts to model phenomenology (material end) or not (functional end). The former is sometimes called "synthetic phenomenology." The upshot of this chapter is that studying consciousness through the design of machines is likely to have two major outcomes. The first is to provide a wide-ranging computational language to express the concept of consciousness. The second is to suggest a wide-ranging set of computational methods for building competent machinery that benefits from the flexibility of conscious representations.

  9. Halo Evolution of Hypereutectic Al-17.5Si Alloy Treated with High-Current Pulsed Electron Beam

    Directory of Open Access Journals (Sweden)

    L. Hu

    2015-01-01

    Full Text Available Halo evolution of an Al-17.5Si alloy surface after treatment with increasing pulse numbers of a high-current pulsed electron beam (HCPEB was investigated. A halo is a ring microstructure resembling a bull’s eye. SEM results indicate that the nanocrystallization of halo induced by HCPEB treatment leads to gradual diffusion of the Si phase. Multiple pulses numbers cause the Si phase to be significantly refined and uniformly distributed. In addition, nanosilicon particles with a grain size of 30~100 nm were formed after HCPEB treatment, as shown by TEM observation. XRD results indicate that Si diffraction peaks broadened after HCPEB treatment. The microhardness tests demonstrate that the microhardness at the midpoint from the halo edge to center decreased sharply from 9770.7 MPa at 5 pulses to 2664.14 MPa at 25 pulses. The relative wear resistance of a 15-pulse sample is effectively improved by a factor of 6.5, exhibiting optimal wear resistance.

  10. Support Spinor Machine

    OpenAIRE

    Kanjamapornkul, Kabin; Pinčák, Richard; Chunithpaisan, Sanphet; Bartoš, Erik

    2017-01-01

    We generalize a support vector machine to a support spinor machine by using the mathematical structure of wedge product over vector machine in order to extend field from vector field to spinor field. The separated hyperplane is extended to Kolmogorov space in time series data which allow us to extend a structure of support vector machine to a support tensor machine and a support tensor machine moduli space. Our performance test on support spinor machine is done over one class classification o...

  11. Genome-Wide Locations of Potential Epimutations Associated with Environmentally Induced Epigenetic Transgenerational Inheritance of Disease Using a Sequential Machine Learning Prediction Approach.

    Directory of Open Access Journals (Sweden)

    M Muksitul Haque

    Full Text Available Environmentally induced epigenetic transgenerational inheritance of disease and phenotypic variation involves germline transmitted epimutations. The primary epimutations identified involve altered differential DNA methylation regions (DMRs. Different environmental toxicants have been shown to promote exposure (i.e., toxicant specific signatures of germline epimutations. Analysis of genomic features associated with these epimutations identified low-density CpG regions (<3 CpG / 100bp termed CpG deserts and a number of unique DNA sequence motifs. The rat genome was annotated for these and additional relevant features. The objective of the current study was to use a machine learning computational approach to predict all potential epimutations in the genome. A number of previously identified sperm epimutations were used as training sets. A novel machine learning approach using a sequential combination of Active Learning and Imbalance Class Learner analysis was developed. The transgenerational sperm epimutation analysis identified approximately 50K individual sites with a 1 kb mean size and 3,233 regions that had a minimum of three adjacent sites with a mean size of 3.5 kb. A select number of the most relevant genomic features were identified with the low density CpG deserts being a critical genomic feature of the features selected. A similar independent analysis with transgenerational somatic cell epimutation training sets identified a smaller number of 1,503 regions of genome-wide predicted sites and differences in genomic feature contributions. The predicted genome-wide germline (sperm epimutations were found to be distinct from the predicted somatic cell epimutations. Validation of the genome-wide germline predicted sites used two recently identified transgenerational sperm epimutation signature sets from the pesticides dichlorodiphenyltrichloroethane (DDT and methoxychlor (MXC exposure lineage F3 generation. Analysis of this positive validation

  12. The shape of the invisible halo: N-body simulations on parallel supercomputers

    Energy Technology Data Exchange (ETDEWEB)

    Warren, M.S.; Zurek, W.H. (Los Alamos National Lab., NM (USA)); Quinn, P.J. (Australian National Univ., Canberra (Australia). Mount Stromlo and Siding Spring Observatories); Salmon, J.K. (California Inst. of Tech., Pasadena, CA (USA))

    1990-01-01

    We study the shapes of halos and the relationship to their angular momentum content by means of N-body (N {approximately} 10{sup 6}) simulations. Results indicate that in relaxed halos with no apparent substructure: (i) the shape and orientation of the isodensity contours tends to persist throughout the virialised portion of the halo; (ii) most ({approx}70%) of the halos are prolate; (iii) the approximate direction of the angular momentum vector tends to persist throughout the halo; (iv) for spherical shells centered on the core of the halo the magnitude of the specific angular momentum is approximately proportional to their radius; (v) the shortest axis of the ellipsoid which approximates the shape of the halo tends to align with the rotation axis of the halo. This tendency is strongest in the fastest rotating halos. 13 refs., 4 figs.

  13. Analysis of machining and machine tools

    CERN Document Server

    Liang, Steven Y

    2016-01-01

    This book delivers the fundamental science and mechanics of machining and machine tools by presenting systematic and quantitative knowledge in the form of process mechanics and physics. It gives readers a solid command of machining science and engineering, and familiarizes them with the geometry and functionality requirements of creating parts and components in today’s markets. The authors address traditional machining topics, such as: single and multiple point cutting processes grinding components accuracy and metrology shear stress in cutting cutting temperature and analysis chatter They also address non-traditional machining, such as: electrical discharge machining electrochemical machining laser and electron beam machining A chapter on biomedical machining is also included. This book is appropriate for advanced undergraduate and graduate mechani cal engineering students, manufacturing engineers, and researchers. Each chapter contains examples, exercises and their solutions, and homework problems that re...

  14. HaloTag as a reporter gene: positron emission tomography imaging with 64Cu-labeled second generation HaloTag ligands

    OpenAIRE

    Hong, Hao; Benink, Hélène A.; Uyeda, H. Tetsuo; Valdovinos, Hector F.; Zhang, Yin; Meisenheimer, Poncho; Barnhart, Todd E.; Fan, Frank; Cai, Weibo

    2013-01-01

    The goal of this study is to employ the HaloTag technology for positron emission tomography (PET), which involves two components: the HaloTag protein (a modified hydrolase which covalently binds to synthetic ligands) and HaloTag ligands (HTLs). 4T1 murine breast cancer cells were stably transfected to express HaloTag protein on the surface (termed as 4T1-HaloTag-ECS, ECS denotes extracellular surface). Two new HTLs were synthesized and termed NOTA-HTL2G-S and NOTA-HTL2G-L (2G indicates second...

  15. Halo formation and evolution: unifying physical properties with structure

    Science.gov (United States)

    Ernest, Alllan David; Collins, Matthew P.

    2015-08-01

    The assembly of matter in the universe proliferates a variety of structures with diverse properties. For example, massive halos of clusters of galaxies have temperatures often an order of magnitude or more higher than the individual galaxy halos within the cluster, or the temperatures of isolated galaxy halos. Giant spiral galaxies contain large quantities of both dark matter and hot gas while other structures like globular clusters appear to have little or no dark matter or gas. Still others, like the dwarf spheroidal galaxies have low gravity and little hot gas, but ironically contain some of the largest fractions of dark matter in the universe. Star forming rates (SFRs) also vary: compare for example the SFRs of giant elliptical galaxies, globular clusters, spiral and starburst galaxies. Furthermore there is evidence that the various structure types have existed over a large fraction of cosmic history. How can this array of variation in properties be reconciled with galaxy halo formation and evolution?We propose a model of halo formation [1] and evolution [2] that is consistent with both primordial nucleosynthesis (BBN) and the isotropies in the cosmic microwave background (CMB). The model uses two simple parameters, the total mass and size of a structure, to (1) explain why galaxies have the fractions of dark matter that they do (including why dwarf spheroidals are so dark matter dominated despite their weak gravity), (2) enable an understanding of the black hole-bulge/black hole-dark halo relations, (3) explain how fully formed massive galaxies can occur so early in cosmic history, (4) understand the connection between spiral and elliptical galaxies (5) unify the nature of globular clusters, dwarf spheroidal galaxies and bulges and (6) predict the temperatures of hot gas halos and understand how cool galaxy halos can remain stable in the hot environments of cluster-galaxy halos.[1] Ernest, A. D., 2012, in Prof. Ion Cotaescu (Ed) Advances in Quantum Theory, pp

  16. The Angular Momentum of Baryons and Dark Matter Halos Revisited

    Science.gov (United States)

    Kimm, Taysun; Devriendt, Julien; Slyz, Adrianne; Pichon, Christophe; Kassin, Susan A.; Dubois, Yohan

    2011-01-01

    Recent theoretical studies have shown that galaxies at high redshift are fed by cold, dense gas filaments, suggesting angular momentum transport by gas differs from that by dark matter. Revisiting this issue using high-resolution cosmological hydrodynamics simulations with adaptive-mesh refinement (AMR), we find that at the time of accretion, gas and dark matter do carry a similar amount of specific angular momentum, but that it is systematically higher than that of the dark matter halo as a whole. At high redshift, freshly accreted gas rapidly streams into the central region of the halo, directly depositing this large amount of angular momentum within a sphere of radius r = 0.1R(sub vir). In contrast, dark matter particles pass through the central region unscathed, and a fraction of them ends up populating the outer regions of the halo (r/R(sub vir) > 0.1), redistributing angular momentum in the process. As a result, large-scale motions of the cosmic web have to be considered as the origin of gas angular momentum rather than its virialised dark matter halo host. This generic result holds for halos of all masses at all redshifts, as radiative cooling ensures that a significant fraction of baryons remain trapped at the centre of the halos. Despite this injection of angular momentum enriched gas, we predict an amount for stellar discs which is in fair agreement with observations at z=0. This arises because the total specific angular momentum of the baryons (gas and stars) remains close to that of dark matter halos. Indeed, our simulations indicate that any differential loss of angular momentum amplitude between the two components is minor even though dark matter halos continuously lose between half and two-thirds of their specific angular momentum modulus as they evolve. In light of our results, a substantial revision of the standard theory of disc formation seems to be required. We propose a new scenario where gas efficiently carries the angular momentum generated

  17. HaloTag technology: a versatile platform for biomedical applications.

    Science.gov (United States)

    England, Christopher G; Luo, Haiming; Cai, Weibo

    2015-06-17

    Exploration of protein function and interaction is critical for discovering links among genomics, proteomics, and disease state; yet, the immense complexity of proteomics found in biological systems currently limits our investigational capacity. Although affinity and autofluorescent tags are widely employed for protein analysis, these methods have been met with limited success because they lack specificity and require multiple fusion tags and genetic constructs. As an alternative approach, the innovative HaloTag protein fusion platform allows protein function and interaction to be comprehensively analyzed using a single genetic construct with multiple capabilities. This is accomplished using a simplified process, in which a variable HaloTag ligand binds rapidly to the HaloTag protein (usually linked to the protein of interest) with high affinity and specificity. In this review, we examine all current applications of the HaloTag technology platform for biomedical applications, such as the study of protein isolation and purification, protein function, protein-protein and protein-DNA interactions, biological assays, in vitro cellular imaging, and in vivo molecular imaging. In addition, novel uses of the HaloTag platform are briefly discussed along with potential future applications.

  18. Deep brain transcranial magnetic stimulation using variable "Halo coil" system

    Science.gov (United States)

    Meng, Y.; Hadimani, R. L.; Crowther, L. J.; Xu, Z.; Qu, J.; Jiles, D. C.

    2015-05-01

    Transcranial Magnetic Stimulation has the potential to treat various neurological disorders non-invasively and safely. The "Halo coil" configuration can stimulate deeper regions of the brain with lower surface to deep-brain field ratio compared to other coil configurations. The existing "Halo coil" configuration is fixed and is limited in varying the site of stimulation in the brain. We have developed a new system based on the current "Halo coil" design along with a graphical user interface system that enables the larger coil to rotate along the transverse plane. The new system can also enable vertical movement of larger coil. Thus, this adjustable "Halo coil" configuration can stimulate different regions of the brain by adjusting the position and orientation of the larger coil on the head. We have calculated magnetic and electric fields inside a MRI-derived heterogeneous head model for various positions and orientations of the coil. We have also investigated the mechanical and thermal stability of the adjustable "Halo coil" configuration for various positions and orientations of the coil to ensure safe operation of the system.

  19. Halo-Independent Direct Detection Analyses Without Mass Assumptions

    CERN Document Server

    Anderson, Adam J.; Kahn, Yonatan; McCullough, Matthew

    2015-10-06

    Results from direct detection experiments are typically interpreted by employing an assumption about the dark matter velocity distribution, with results presented in the $m_\\chi-\\sigma_n$ plane. Recently methods which are independent of the DM halo velocity distribution have been developed which present results in the $v_{min}-\\tilde{g}$ plane, but these in turn require an assumption on the dark matter mass. Here we present an extension of these halo-independent methods for dark matter direct detection which does not require a fiducial choice of the dark matter mass. With a change of variables from $v_{min}$ to nuclear recoil momentum ($p_R$), the full halo-independent content of an experimental result for any dark matter mass can be condensed into a single plot as a function of a new halo integral variable, which we call $\\tilde{h}(p_R)$. The entire family of conventional halo-independent $\\tilde{g}(v_{min})$ plots for all DM masses are directly found from the single $\\tilde{h}(p_R)$ plot through a simple re...

  20. ITER design features serving for suppression of eddy- and halo related electromagnetic loads

    Energy Technology Data Exchange (ETDEWEB)

    Sadakov, S., E-mail: sergey.sadakov@iter.org [ITER Organization, Route de Vinon-sur-Verdon – CS 90 046, 13067 St. Paul-Lez-Durance Cedex (France); Furmanek, A.; Calcagno, B. [ITER Organization, Route de Vinon-sur-Verdon – CS 90 046, 13067 St. Paul-Lez-Durance Cedex (France); Bertolini, C. [Blanket Integrated Product Team, 23087 Merate (Italy); Khomiakov, S.; Kolganov, V.; Poddubnyi, I. [Open Joint-Stock Company ' ' N.A. Dollezhal Research and Development Institute of Power Engineering' ' , Blanket Integrated Product Team, NIKIET, Malaya Krasnoselskaya Str. 2/8, Moscow 107140 (Russian Federation)

    2015-10-15

    Highlights: • One of main challenges in tokamaks is to suppress EM loads created in in-vessel parts. • This article explains examples on how such suppression was achieved by design means. • Described principles helped suppress loads in several folds, up to an order magnitude. • Described principles do open a path to robust design of various in-vessel parts in ITER. • Being quite generic, these principles may be used in various industrial applications. - Abstract: As any tokamak, ITER will operate with rather high magnetic fields. Quasi-static toroidal field inside of the vacuum vessel reaches ∼9 T and slow transient poloidal field ∼2.5 T. In a case of plasma vertical drift and disruption, characteristic times of magnetic fields variation are short: 1–2 ms at thermal quench phase and 10–300 ms at current quench phase, thus magnetic field derivative reaches 50–150 T/s. These fast transients induce intensive currents and ElectroMagnetic (EM) loads in conductive structures. EM loads at in-vessel components typically exceed gravity and seismic loads by two orders of magnitude. Induced currents are split in two groups: eddy currents closed completely in conductive structures, and halo currents closed partly through plasma periphery and partly through structures. This article describes various design features serving for suppression of eddy- and halo related EM loads in ITER. Parallel slits and various kinds of reshaping help suppress eddy related EM loads in massive parts such as shield blocks and first wall panels. A principle of force- and torque-free current paths is used in electrical straps passing pre-defined waveforms of halo and eddy currents. Multiple electro-insulating breaks were proven necessary to suppress eddy related EM loads at blanket manifolds. In all listed cases workable design solutions have been found in a frame of pre-defined tight interfaces.

  1. Properties of dark matter haloes as a function of local environment density

    Science.gov (United States)

    Lee, Christoph T.; Primack, Joel R.; Behroozi, Peter; Rodríguez-Puebla, Aldo; Hellinger, Doug; Dekel, Avishai

    2017-04-01

    We study how properties of discrete dark matter haloes depend on halo environment, characterized by the mass density around the haloes on scales from 0.5 to 16 h-1 Mpc. We find that low-mass haloes (those less massive than the characteristic mass MC of haloes collapsing at a given epoch) in high-density environments have lower accretion rates, lower spins, higher concentrations and rounder shapes than haloes in median density environments. Haloes in median- and low-density environments have similar accretion rates and concentrations, but haloes in low-density environments have lower spins and are more elongated. Haloes of a given mass in high-density regions accrete material earlier than haloes of the same mass in lower density regions. All but the most massive haloes in high-density regions are losing mass (i.e. being stripped) at low redshifts, which causes artificially lowered NFW scale radii and increased concentrations. Tidal effects are also responsible for the decreasing spins of low-mass haloes in high-density regions at low redshifts z spins because they lack nearby haloes whose tidal fields can spin them up. We also show that the simulation density distribution is well fit by an extreme value distribution, and that the density distribution becomes broader with cosmic time.

  2. Subdural abscess associated with halo-pin traction.

    Science.gov (United States)

    Garfin, S R; Botte, M J; Triggs, K J; Nickel, V L

    1988-10-01

    Osteomyelitis and intracranial abscess are among the most serious complications that have been reported in association with the use of the halo device. The cases of five patients who had formation of an intracranial abscess related to the use of a halo cervical immobilizer are described. All of the infections resolved after drainage of the abscess, débridement, and parenteral administration of antibiotics. Meticulous care of the pin sites is essential to avoid this serious complication. Additionally, since all of the infections were associated with prolonged halo-skeletal traction, this technique should be used with caution and with an awareness of the possible increased risks of pin-site infection and of formation of a subdural abscess.

  3. Direct photoassociation of halo molecules in ultracold 86 Sr

    Science.gov (United States)

    Aman, J. A.; Hill, Joshua; Killian, T. C.

    2017-04-01

    We investigate the creation of 1S0 +1S0 halo molecules in strontium 86 through direct photoassociation in an optical dipole trap. We drive two photon Raman transitions near-resonance with a molecular level of the 1S0 +3P1 interatomic potential as the intermediate state. This provides large Frank-Condon factors and allows us to observe resonances for the creation of halo molecules through higher order Raman processes. The halo molecule is bound by EB 85 kHz at low excitation-laser intensity, but experiments show large AC Stark shifts of the molecular binding energy. These conditions suggest that STIRAP should be very effective for improving molecular conversion efficiency. Further experiments in a 3D lattice will explore molecular lifetimes and collision rates. Travel support provided by Shell Corporation.

  4. Axionic dark matter signatures in various halo models

    Energy Technology Data Exchange (ETDEWEB)

    Vergados, J.D., E-mail: vergados@uoi.gr [Center for Axion and Precision Physics Research, Institute for Basic Science (IBS), Daejeon 34141 (Korea, Republic of); Department of Physics, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141 (Korea, Republic of); ARC Centre of Excellence in Particle Physics at the Terascale and Centre for the Subatomic Structure of Matter (CSSM), University of Adelaide, Adelaide SA 5005 (Australia); Semertzidis, Y.K. [Center for Axion and Precision Physics Research, Institute for Basic Science (IBS), Daejeon 34141 (Korea, Republic of); Department of Physics, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141 (Korea, Republic of)

    2017-02-15

    In the present work we study possible signatures in the Axion Dark Matter searches. We focus on the dependence of the expected width in resonant cavities for various popular halo models, leading to standard velocity distributions, e.g. Maxwell–Boltzmann, as well as phase-mixed and non-virialized axionic dark matter (flows, caustic rings). We study, in particular, the time dependence of the resonance width (modulation) arising from such models. We find that the difference between the maximum (in June) and the minimum (in December) can vary by about 10% in the case of standard halos. In the case of mixed phase halos the variation is a bit bigger and for caustic rings the maximum is expected to occur a bit later. Experimentally such a modulation is observable with present technology.

  5. Particle ejection during mergers of dark matter halos

    Energy Technology Data Exchange (ETDEWEB)

    Carucci, Isabella P.; Sparre, Martin; Hansen, Steen H. [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, Juliane Maries Vej 30, Copenhagen, 2100 Denmark (Denmark); Joyce, Michael, E-mail: carucci@dark-cosmology.dk, E-mail: sparre@dark-cosmology.dk, E-mail: hansen@dark-cosmology.dk, E-mail: joyce@lpnhe.in2p3.fr [Laboratoire de Physique Nucléaire et Hautes Énergies, Université Pierre et Marie Curie - Paris 6, CNRS IN2P3 UMR 7585, 4 Place Jussieu, Paris Cedex 05, 75752 France (France)

    2014-06-01

    Dark matter halos are built from accretion and merging. During merging some of the dark matter particles may be ejected with velocities higher than the escape velocity. We use both N-body simulations and single-particle smooth-field simulations to demonstrate that rapid changes to the mean field potential are responsible for such ejection, and in particular that dynamical friction plays no significant role in it. Studying a range of minor mergers, we find that typically between 5–15% of the particles from the smaller of the two merging structures are ejected. We also find that the ejected particles originate essentially from the small halo, and more specifically are particles in the small halo which pass later through the region in which the merging occurs.

  6. Simulation Studies of the Helium and Lead Observatory (HALO)

    Science.gov (United States)

    Sanford, Nikki; Scholberg, Kate

    2012-10-01

    Simulation studies for were conducted for the Helium and Lead Observatory (HALO), the supernova neutrino detector at SNOLAB, Sudbury, Ontario. HALO consists of 79 tons of lead, with 128 ^3He counters which detect the scattered lead neutrons resulting from incoming neutrinos. Improvements were made to the Geant4 Monte Carlo simulation's geometry by the addition of water boxes and plastic baseboards, which serve to reflect scattered neutrons back towards counters, and shield against outside neutrons and gammas. Several box designs were created, and the resulting event detection efficiencies and labeling of 1n and 2n events were studied. It was found that these additions cause a 2% efficiency increase, a slight improvement of correctly labeled events, and are a significant improvement to the HALO simulation.

  7. Reactions of Proton Halo Nuclei in a Relativistic Optical Potential

    CERN Document Server

    Rashdan, M

    2003-01-01

    The reaction cross section, sigma sub R; of the proton halo nuclei sup 1 sup 7 Ne and sup 1 sup 2 N on Si is calculated using an optical potential derived from the solution of the Dirac-Brueckner-Bethe-Goldstone equation, starting from the one-boson-exchange potential of Bonn. The nuclear densities are generated from self-consistent Hartree-Fock calculations using the recent Skyrme interaction SKRA. It is found that the enhancement in the reaction cross section found experimentally for the sup 1 sup 7 Ne + Si system in comparison to sup 1 sup 5 O + Si, where sup 1 sup 5 O has been considered as a core of sup 1 sup 7 Ne, is mainly due to the proton halo structure of sup 1 sup 7 Ne which increases the interaction, in the surface and tail regions. Glauber model calculations did not produce this enhancement in sigma sub R for proton halo nuclei

  8. Research progress of machine tool thermal error modeling technology

    Directory of Open Access Journals (Sweden)

    Qianjian GUO

    2015-08-01

    Full Text Available During cutting, machine tools are influenced by different heat sources, which induces machine thermal deformation, deviation and thermal error. In different machine errors, thermal error accounts for 40%~70% of total machine errors, which is the main influence factor of machining accuracy. In order to reduce machine thermal error and improve machining precision, there are mainly 3 ways at present: 1 Improving machine thermal stiffness by optimal design of machine structure; 2 Separating heat sources from machine tools; 3 Thermal error compensation, which reduces the influence of thermal distortions by predicting and compensating measures. In order to compensate thermal errors, thermal error modeling is the premise and foundation. Therefore, thermal error modeling technology is introduced in this paper firstly, and its recent development both at home and abroad is analyzed. The main obstacles in thermal error modeling field at present are summerized, and the future of the technology are presented.

  9. Machine musicianship

    Science.gov (United States)

    Rowe, Robert

    2002-05-01

    The training of musicians begins by teaching basic musical concepts, a collection of knowledge commonly known as musicianship. Computer programs designed to implement musical skills (e.g., to make sense of what they hear, perform music expressively, or compose convincing pieces) can similarly benefit from access to a fundamental level of musicianship. Recent research in music cognition, artificial intelligence, and music theory has produced a repertoire of techniques that can make the behavior of computer programs more musical. Many of these were presented in a recently published book/CD-ROM entitled Machine Musicianship. For use in interactive music systems, we are interested in those which are fast enough to run in real time and that need only make reference to the material as it appears in sequence. This talk will review several applications that are able to identify the tonal center of musical material during performance. Beyond this specific task, the design of real-time algorithmic listening through the concurrent operation of several connected analyzers is examined. The presentation includes discussion of a library of C++ objects that can be combined to perform interactive listening and a demonstration of their capability.

  10. Addiction Machines

    Directory of Open Access Journals (Sweden)

    James Godley

    2011-10-01

    Full Text Available Entry into the crypt William Burroughs shared with his mother opened and shut around a failed re-enactment of William Tell’s shot through the prop placed upon a loved one’s head. The accidental killing of his wife Joan completed the installation of the addictation machine that spun melancholia as manic dissemination. An early encryptment to which was added the audio portion of abuse deposited an undeliverable message in WB. Wil- liam could never tell, although his corpus bears the in- scription of this impossibility as another form of pos- sibility. James Godley is currently a doctoral candidate in Eng- lish at SUNY Buffalo, where he studies psychoanalysis, Continental philosophy, and nineteenth-century litera- ture and poetry (British and American. His work on the concept of mourning and “the dead” in Freudian and Lacanian approaches to psychoanalytic thought and in Gothic literature has also spawned an essay on zombie porn. Since entering the Academy of Fine Arts Karlsruhe in 2007, Valentin Hennig has studied in the classes of Sil- via Bächli, Claudio Moser, and Corinne Wasmuht. In 2010 he spent a semester at the Dresden Academy of Fine Arts. His work has been shown in group exhibi- tions in Freiburg and Karlsruhe.

  11. Three-body halo nuclei in an effective theory framework

    Energy Technology Data Exchange (ETDEWEB)

    Canham, David L.

    2009-05-20

    The universal properties and structure of halo nuclei composed of two neutrons (2n) and a core are investigated within an effective quantum mechanics framework. We construct an effective interaction potential that exploits the separation of scales in halo nuclei and treat the nucleus as an effective three-body system, which to leading order is described by the large S-wave scattering lengths in the underlying two-body subsystems. The uncertainty from higher orders in the expansion is quantified through theoretical error bands. First, we investigate the possibility to observe excited Efimov states in 2n halo nuclei. Based on the experimental data, {sup 20}C is the only halo nucleus candidate to possibly have an Efimov excited state, with an energy less than 7 keV below the scattering threshold. Second, we study the structure of {sup 20}C and other 2n halo nuclei. In particular, we calculate their matter density form factors, radii, and two-neutron opening angles. We then make a systematic improvement upon these calculations by extending the effective potential to the next-to-leading order. To this order, we require an additional two-body parameter, which we tune to the effective range of the interaction. In addition to range corrections to the 2n halo nuclei results, we show corrections to the Efimov effect in the three-boson system. Furthermore, we explore universality in the linear range corrections to the Efimov spectrum. Finally, we study the scattering of D{sup 0} and D{sup *0} mesons and their antiparticles off the X(3872) in an effective field theory for short-range interactions. We present results for the S-wave scattering amplitude, total interaction cross section and S-wave scattering length. (orig.)

  12. Capacity of straylight and disk halo size to diagnose cataract.

    Science.gov (United States)

    Palomo-Álvarez, Catalina; Puell, María C

    2015-10-01

    To examine the capacity of straylight and disk halo size to diagnose cataract. Faculty of Optics and Optometry, Universidad Complutense de Madrid, Spain. Prospective study. Straylight, disk halo radius, and high-contrast corrected distance visual acuity (CDVA) measurements were compared between patients with age-related cataract and age-matched normal-sighted control subjects by calculating the area under the curve (AUC) receiver operating characteristic. Measurements were made in 53 eyes of 53 patients with a mean age of 67.94 years ± 7.11 (SD) and 31 eyes of 31 controls with a mean age 66.06 ± 5.43 years. Significantly worse (P cataract group than in the control group (1.17 ± 0.11 log[s], 2.10 ± 0.16 log arcmin, and 0.08 ± 0.08 logMAR). Significant differences in AUCs were observed for disk halo radius (0.89 ± 0.04) versus straylight (0.77 ± 0.05) (P = .03) and disk halo radius versus CDVA (0.72 ± 0.05) (P = .001). The comparison of disk halo radius versus the discriminant function with input from CDVA and straylight (0.80 ± 0.05) was at the limit of significance only (0.091 ± 0.05, P = .051). Although all 3 variables discriminated well between normal eyes and eyes with cataract, the disk halo radius showed the best diagnostic capacity. Neither author has a financial or proprietary interest in any material or method mentioned. Copyright © 2015 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  13. The orbital eccentricity distribution of solar-neighbourhood halo stars

    Science.gov (United States)

    Hattori, K.; Yoshii, Y.

    2011-12-01

    We present theoretical calculations for the differential distribution of stellar orbital eccentricity for a sample of solar-neighbourhood halo stars. Two types of static, spherical gravitational potentials are adopted to define the eccentricity e for given energy E and angular momentum L, such as an isochrone potential and a Navarro-Frenk-White potential that can serve as two extreme ends covering in between any realistic potential of the Milky Way halo. The solar-neighbourhood eccentricity distribution ΔN(e) is then formulated, based on a static distribution function of the form f(E, L) in which the velocity anisotropy parameter β monotonically increases in the radial direction away from the galaxy centre, such that β is below unity (near-isotropic velocity dispersion) in the central region and asymptotically approaches ˜1 (radially anisotropic velocity dispersion) in the far distant region of the halo. We find that ΔN(e) sensitively depends upon the radial profile of β, and this sensitivity is used to constrain such a profile in comparison with some observational properties of ΔNobs(e) recently reported by Carollo et al. In particular, the linear e-distribution and the fraction of higher e stars for their sample of solar-neighbourhood inner-halo stars rule out a constant profile of β, contrary to the opposite claim by Bond et al. Our constraint of β≲ 0.5 at the galaxy centre indicates that the violent relaxation that has acted on the inner halo is effective within a scale radius of ˜10 kpc from the galaxy centre. We argue that our result would help to understand the formation and evolution of the Milky Way halo.

  14. The Halo Boundary of Galaxy Clusters in the SDSS

    Energy Technology Data Exchange (ETDEWEB)

    Baxter, Eric; Jain, Bhuvnesh; Sheth, Ravi K. [Center for Particle Cosmology, Department of Physics, University of Pennsylvania, Philadelphia, PA 19104 (United States); Chang, Chihway; Kravtsov, Andrey [Kavli Institute for Cosmological Physics, The University of Chicago, Chicago, IL 60637 (United States); Adhikari, Susmita; Dalal, Neal [Department of Astronomy, University of Illinois at Urbana-Champaign, Champaign, IL 61801 (United States); More, Surhud [Kavli Institute for the Physics and Mathematics of the Universe (WPI), Tokyo Institutes for Advanced Study, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa-shi, Chiba, 277-8583 (Japan); Rozo, Eduardo [Department of Physics, University of Arizona, Tucson, AZ 85721 (United States); Rykoff, Eli, E-mail: ebax@sas.upenn.edu [Kavli Institute for Particle Astrophysics and Cosmology, P.O. Box 2450, Stanford University, Stanford, CA 94305 (United States)

    2017-05-20

    Analytical models and simulations predict a rapid decline in the halo density profile associated with the transition from the “infalling” regime outside the halo to the “collapsed” regime within the halo. Using data from SDSS, we explore evidence for such a feature in the density profiles of galaxy clusters using several different approaches. We first estimate the steepening of the outer galaxy density profile around clusters, finding evidence for truncation of the halo profile. Next, we measure the galaxy density profile around clusters using two sets of galaxies selected on color. We find evidence of an abrupt change in galaxy colors that coincides with the location of the steepening of the density profile. Since galaxies that have completed orbits within the cluster are more likely to be quenched of star formation and thus appear redder, this abrupt change in galaxy color can be associated with the transition from single-stream to multi-stream regimes. We also use a standard model comparison approach to measure evidence for a “splashback”-like feature, but find that this approach is very sensitive to modeling assumptions. Finally, we perform measurements using an independent cluster catalog to test for potential systematic errors associated with cluster selection. We identify several avenues for future work: improved understanding of the small-scale galaxy profile, lensing measurements, identification of proxies for the halo accretion rate, and other tests. With upcoming data from the DES, KiDS, and HSC surveys, we can expect significant improvements in the study of halo boundaries.

  15. The FUSE Survey of 0 VI in the Galactic Halo

    Science.gov (United States)

    Sonneborn, George; Savage, B. D.; Wakker, B. P.; Sembach, K. R.; Jenkins, E. B.; Moos, H. W.; Shull, J. M.

    2003-01-01

    This paper summarizes the results of the Far-Ultraviolet Spectroscopic Explorer (FUSE) program to study 0 VI in the Milky Way halo. Spectra of 100 extragalactic objects and two distant halo stars are analyzed to obtain measures of O VI absorption along paths through the Milky Way thick disk/halo. Strong O VI absorption over the velocity range from -100 to 100 km/s reveals a widespread but highly irregular distribution of O VI, implying the existence of substantial amounts of hot gas with T approx. 3 x 10(exp 5) K in the Milky Way thick disk/halo. The overall distribution of O VI is not well described by a symmetrical plane-parallel layer of patchy O VI absorption. The simplest departure from such a model that provides a reasonable fit to the observations is a plane-parallel patchy absorbing layer with an average O VI mid-plane density of n(sub 0)(O VI) = 1.7 x 10(exp -2)/cu cm, a scale height of approx. 2.3 kpc, and a approx. 0.25 dex excess of O VI in the northern Galactic polar region. The distribution of O VI over the sky is poorly correlated with other tracers of gas in the halo, including low and intermediate velocity H I, Ha emission from the warm ionized gas at approx. l0(exp 4) K, and hot X-ray emitting gas at approx. l0(exp 6) K . The O VI has an average velocity dispersion, b approx. 60 km/s and standard deviation of 15 km/s. Thermal broadening alone cannot explain the large observed profile widths. A combination of models involving the radiative cooling of hot fountain gas, the cooling of supernova bubbles in the halo, and the turbulent mixing of warm and hot halo gases is required to explain the presence of O VI and other highly ionized atoms found in the halo. The preferential venting of hot gas from local bubbles and superbubbles into the northern Galactic polar region may explain the enhancement of O VI in the North.

  16. Two distinct halo populations in the solar neighborhood. IV

    DEFF Research Database (Denmark)

    Nissen, P. E.; Schuster, W. J.

    2012-01-01

    We investigate if there is a difference in the lithium abundances of stars belonging to two halo populations of F and G main-sequence stars previously found to differ in [alpha/Fe] for the metallicity range -1.4 ...-resolution spectra using MARCS model atmospheres. Furthermore, masses of the stars are determined from the logTeff - logg diagram by interpolating between Yonsei-Yale evolutionary tracks. There is no significant systematic difference in the lithium abundances of high- and low-alpha halo stars. For the large majority...

  17. Dynamical Constraints On The Galaxy-Halo Connection

    Science.gov (United States)

    Desmond, Harry

    2017-07-01

    Dark matter halos comprise the bulk of the universe's mass, yet must be probed by the luminous galaxies that form within them. A key goal of modern astrophysics, therefore, is to robustly relate the visible and dark mass, which to first order means relating the properties of galaxies and halos. This may be expected not only to improve our knowledge of galaxy formation, but also to enable high-precision cosmological tests using galaxies and hence maximise the utility of future galaxy surveys. As halos are inaccessible to observations - as galaxies are to N-body simulations - this relation requires an additional modelling step.The aim of this thesis is to develop and evaluate models of the galaxy-halo connection using observations of galaxy dynamics. In particular, I build empirical models based on the technique of halo abundance matching for five key dynamical scaling relations of galaxies - the Tully-Fisher, Faber-Jackson, mass-size and mass discrepancy-acceleration relations, and Fundamental Plane - which relate their baryon distributions and rotation or velocity dispersion profiles. I then develop a statistical scheme based on approximate Bayesian computation to compare the predicted and measured values of a number of summary statistics describing the relations' important features. This not only provides quantitative constraints on the free parameters of the models, but also allows absolute goodness-of-fit measures to be formulated. I find some features to be naturally accounted for by an abundance matching approach and others to impose new constraints on the galaxy-halo connection; the remainder are challenging to account for and may imply galaxy-halo correlations beyond the scope of basic abundance matching.Besides providing concrete statistical tests of specific galaxy formation theories, these results will be of use for guiding the inputs of empirical and semi-analytic galaxy formation models, which require galaxy-halo correlations to be imposed by hand. As

  18. Nonlinear machine learning and design of reconfigurable digital colloids.

    Science.gov (United States)

    Long, Andrew W; Phillips, Carolyn L; Jankowksi, Eric; Ferguson, Andrew L

    2016-09-14

    Digital colloids, a cluster of freely rotating "halo" particles tethered to the surface of a central particle, were recently proposed as ultra-high density memory elements for information storage. Rational design of these digital colloids for memory storage applications requires a quantitative understanding of the thermodynamic and kinetic stability of the configurational states within which information is stored. We apply nonlinear machine learning to Brownian dynamics simulations of these digital colloids to extract the low-dimensional intrinsic manifold governing digital colloid morphology, thermodynamics, and kinetics. By modulating the relative size ratio between halo particles and central particles, we investigate the size-dependent configurational stability and transition kinetics for the 2-state tetrahedral (N = 4) and 30-state octahedral (N = 6) digital colloids. We demonstrate the use of this framework to guide the rational design of a memory storage element to hold a block of text that trades off the competing design criteria of memory addressability and volatility.

  19. Toward a Combined SAGE II-HALOE Aerosol Climatology: An Evaluation of HALOE Version 19 Stratospheric Aerosol Extinction Coefficient Observations

    Science.gov (United States)

    Thomason, L. W.

    2012-01-01

    Herein, the Halogen Occultation Experiment (HALOE) aerosol extinction coefficient data is evaluated in the low aerosol loading period after 1996 as the first necessary step in a process that will eventually allow the production of a combined HALOE/SAGE II (Stratospheric Aerosol and Gas Experiment) aerosol climatology of derived aerosol products including surface area density. Based on these analyses, it is demonstrated that HALOE's 3.46 microns is of good quality above 19 km and suitable for scientific applications above that altitude. However, it is increasingly suspect at lower altitudes and should not be used below 17 km under any circumstances after 1996. The 3.40 microns is biased by about 10% throughout the lower stratosphere due to the failure to clear NO2 but otherwise appears to be a high quality product down to 15 km. The 2.45 and 5.26 micron aerosol extinction coefficient measurements are clearly biased and should not be used for scientific applications after the most intense parts of the Pinatubo period. Many of the issues in the aerosol data appear to be related to either the failure to clear some interfering gas species or doing so poorly. For instance, it is clear that the 3.40micronaerosol extinction coefficient measurements can be improved through the inclusion of an NO2 correction and could, in fact, end up as the highest quality overall HALOE aerosol extinction coefficient measurement. It also appears that the 2.45 and 5.26 micron channels may be improved by updating the Upper Atmosphere Pilot Database which is used as a resource for the removal of gas species otherwise not available from direct HALOE measurements. Finally, a simple model to demonstrate the promise of mixed visible/infrared aerosol extinction coefficient ensembles for the retrieval of bulk aerosol properties demonstrates that a combined HALOE/SAGE II aerosol climatology is feasible and may represent a substantial improvement over independently derived data sets.

  20. HaloTag: a novel reporter gene for positron emission tomography

    OpenAIRE

    Hong, Hao; Benink, Hélène A.; Zhang, Yin; Yang, Yunan; Uyeda, H. Tetsuo; Engle, Jonathan W.; Severin, Gregory W.; McDougall, Mark G; Barnhart, Todd E.; Klaubert, Dieter H.; Nickles, Robert J; Fan, Frank; Cai, Weibo

    2011-01-01

    Among the many molecular imaging techniques, reporter gene imaging has been a dynamic area of research. The HaloTag protein is a modified haloalkane dehalogenase which was designed to covalently bind to synthetic ligands (i.e. the HaloTag ligands [HTL]). Covalent bond formation between the HaloTag protein and the chloroal-kane within the HTL occurs rapidly under physiological conditions, which is highly specific and essentially irreversible. Over the years, HaloTag technology has been investi...

  1. Resolution of vitiligo following excision of halo congenital melanocytic nevus: a rare case report.

    Science.gov (United States)

    Wang, Kai; Wang, Zhi; Huang, Weiqing

    2016-05-01

    Halo congenital melanocytic nevus (CMN) associated with vitiligo is rare, especially with regard to CMN excision. Only two reports of excision of halo CMN following repigmentation of vitiligo are found in the literature. We present a case of a girl with halo CMN and periorbital vitiligo. The halo CMN was excised and followed by spontaneous improvement of vitiligo. The result suggests excision of the inciting lesion may be a promising way to control vitiligo. © 2015 Wiley Periodicals, Inc.

  2. Laser machining of advanced materials

    CERN Document Server

    Dahotre, Narendra B

    2011-01-01

    Advanced materialsIntroductionApplicationsStructural ceramicsBiomaterials CompositesIntermetallicsMachining of advanced materials IntroductionFabrication techniquesMechanical machiningChemical Machining (CM)Electrical machiningRadiation machining Hybrid machiningLaser machiningIntroductionAbsorption of laser energy and multiple reflectionsThermal effectsLaser machining of structural ceramicsIntrodu

  3. De bepaling van halo-azijnzuren, chloriet en chloraat in drinkwater

    NARCIS (Netherlands)

    Peters RJB; van de Meer-Arp KKM; Versteegh JFM

    1990-01-01

    A method was developed to determine halo-acetic acids with a detection limit of 0.1 mug/L. Halo-acetic acids were determined in samples drinking water derived from surface- and bankfiltrated water however, not in drinking water derived from groundwater. Halo-acetic acids were found in chlorinated

  4. Describing one-and two-neutron halos in effective field theory

    Indian Academy of Sciences (India)

    2014-11-01

    Nov 1, 2014 ... Click here to view fulltext PDF ... In this paper, the recent work our group has undertaken on effective field theory (EFT) analyses of experimental data pertaining to one- and two-neutron halo nuclei is discussed. The cases of 19C and 8Li (one-neutron halos) and 22C (two-neutron halo) are considered.

  5. Molecular machines open cell membranes

    Science.gov (United States)

    García-López, Víctor; Chen, Fang; Nilewski, Lizanne G.; Duret, Guillaume; Aliyan, Amir; Kolomeisky, Anatoly B.; Robinson, Jacob T.; Wang, Gufeng; Pal, Robert; Tour, James M.

    2017-08-01

    Beyond the more common chemical delivery strategies, several physical techniques are used to open the lipid bilayers of cellular membranes. These include using electric and magnetic fields, temperature, ultrasound or light to introduce compounds into cells, to release molecular species from cells or to selectively induce programmed cell death (apoptosis) or uncontrolled cell death (necrosis). More recently, molecular motors and switches that can change their conformation in a controlled manner in response to external stimuli have been used to produce mechanical actions on tissue for biomedical applications. Here we show that molecular machines can drill through cellular bilayers using their molecular-scale actuation, specifically nanomechanical action. Upon physical adsorption of the molecular motors onto lipid bilayers and subsequent activation of the motors using ultraviolet light, holes are drilled in the cell membranes. We designed molecular motors and complementary experimental protocols that use nanomechanical action to induce the diffusion of chemical species out of synthetic vesicles, to enhance the diffusion of traceable molecular machines into and within live cells, to induce necrosis and to introduce chemical species into live cells. We also show that, by using molecular machines that bear short peptide addends, nanomechanical action can selectively target specific cell-surface recognition sites. Beyond the in vitro applications demonstrated here, we expect that molecular machines could also be used in vivo, especially as their design progresses to allow two-photon, near-infrared and radio-frequency activation.

  6. Prospects for detecting supersymmetric dark matter in the Galactic halo

    NARCIS (Netherlands)

    Springel, V.; White, S. D. M.; Frenk, C. S.; Navarro, J. F.; Jenkins, A.; Vogelsberger, M.; Wang, J.; Ludlow, A.; Helmi, A.

    2008-01-01

    Dark matter is the dominant form of matter in the Universe, but its nature is unknown. It is plausibly an elementary particle, perhaps the lightest supersymmetric partner of known particle species(1). In this case, annihilation of dark matter in the halo of the Milky Way should produce gamma-rays at

  7. The Galactic Halo in Mixed Dark Matter Cosmologies

    NARCIS (Netherlands)

    Anderhalden, D.; Diemand, J.; Bertone, G.; Macciò, A.V.; Schneider, A.

    2012-01-01

    A possible solution to the small scale problems of the cold dark matter (CDM) scenario is that the dark matter consists of two components, a cold and a warm one. We perform a set of high resolution simulations of the Milky Way halo varying the mass of the WDM particle (mWDM) and the cosmic dark

  8. The prolate shape of the galactic dark-matter halo

    NARCIS (Netherlands)

    Helmi, A; Spooner, NJC; Kudryavtsev,

    2005-01-01

    Knowledge of the distribution of dark-matter in our Galaxy plays a crucial role in the interpretation of dark-matter detection experiments. I will argue here that probably the best way of constraining the properties of the dark-matter halo is through astrophysical observations. These provide

  9. Redshift space bias and beta from the halo model

    OpenAIRE

    Seljak, Uros

    2000-01-01

    We analyze scale dependence of redshift space bias $b$ and $\\beta \\equiv \\Omega_m^{0.6}/b$ in the context of the halo model. We show that linear bias is a good approximation only on large scales, for $k

  10. Lithium abundances in high- and low-alpha halo stars

    DEFF Research Database (Denmark)

    Nissen, P. E.; Schuster, W. J.

    2012-01-01

    A previous study of F and G main-sequence stars in the solar neighborhood has revealed the existence of two distinct halo populations with a clear separation in [alpha /Fe] for the metallicity range -1.4 < [Fe/H] < -0.7. The kinematics of the stars and models of galaxy formation suggest that the ...

  11. On the shape of the Galactic dark matter halo

    NARCIS (Netherlands)

    Helmi, A

    2004-01-01

    The confined nature of the debris from the Sagittarius dwarf to a narrow trail on the sky has recently prompted the suggestion that the dark matter halo of our Galaxy should be nearly spherical (Ibata et al. 2001; Majewski et al. 2003). This would seem to be in strong contrast with predictions from

  12. Jet interactions with the hot halos of clusters and galaxies

    NARCIS (Netherlands)

    McNamara, B.R.; Bîrzan, L.; Rafferty, D.A.; Nulsen, P.E.J.; Carilli, C.; Wise, M.W.

    2008-01-01

    X-ray observations of cavities and shock fronts produced by jets streaming through hot halos have significantly advanced our understanding of the energetics and dynamics of extragalactic radio sources. Radio sources at the centers of clusters have dynamical ages between ten and several hundred

  13. A halo model for cosmological neutral hydrogen : abundances and clustering

    Science.gov (United States)

    Padmanabhan, Hamsa; Refregier, Alexandre; Amara, Adam

    2017-08-01

    We extend the results of previous analyses towards constraining the abundance and clustering of post-reionization (z ∼ 0-5) neutral hydrogen (H i) systems using a halo model framework. We work with a comprehensive H I data set including the small-scale clustering, column density and mass function of H I galaxies at low redshifts, intensity mapping measurements at intermediate redshifts and the ultraviolet/optical observations of Damped Lyman Alpha (DLA) systems at higher redshifts. We use a Markov Chain Monte Carlo (MCMC) approach to constrain the parameters of the best-fitting models, both for the H i-halo mass (HIHM) relation and the H I radial density profile. We find that a radial exponential profile results in a good fit to the low-redshift H I observations, including the clustering and the column density distribution. The form of the profile is also found to match the high-redshift DLA observations, when used in combination with a three-parameter HIHM relation and a redshift evolution in the H I concentration. The halo model predictions are in good agreement with the observed H I surface density profiles of low-redshift galaxies, and the general trends in the impact parameter and covering fraction observations of high-redshift DLAs. We provide convenient tables summarizing the best-fitting halo model predictions.

  14. The Disk Mass Project: breaking the disk-halo degeneracy

    NARCIS (Netherlands)

    Verheijen, Marc A. W.; Bershady, Matthew A.; Swaters, Rob A.; Andersen, David R.; Westfall, Kyle B.; DE JONG, R. S.

    2007-01-01

    Little is known about the content and distribution of dark matter in spiral galaxies. To break the degeneracy in galaxy rotation curve decompositions, which allows a wide range of dark matter halo density profiles, an independent measure of the mass surface density of stellar disks is needed. Here,

  15. Halo-like structures studied by atomic force microscopy

    DEFF Research Database (Denmark)

    Sørensen, Alexis Hammer; Kyhle, Anders; Hansen, L. Theil

    1997-01-01

    Nanometer-sized clusters of copper have been produced in a hollow cathode sputtering source and deposited on SiOx. Halo-like structures consisting of micrometer sized protrusions in the solicon oxide surface surrounded by thin rings of smaller particles are observed. The area in between seems...

  16. The influence of halo evolution on galaxy structure

    Science.gov (United States)

    White, Simon

    2015-03-01

    If Einstein-Newton gravity holds on galactic and larger scales, then current observations demonstrate that the stars and interstellar gas of a typical bright galaxy account for only a few percent of its total nonlinear mass. Dark matter makes up the rest and cannot be faint stars or any other baryonic form because it was already present and decoupled from the radiation plasma at z = 1000, long before any nonlinear object formed. The weak gravito-sonic waves so precisely measured by CMB observations are detected again at z = 4 as order unity fluctuations in intergalactic matter. These subsequently collapse to form today's galaxy/halo systems, whose mean mass profiles can be accurately determined through gravitational lensing. High-resolution simulations link the observed dark matter structures seen at all these epochs, demonstrating that they are consistent and providing detailed predictions for all aspects of halo structure and growth. Requiring consistency with the abundance and clustering of real galaxies strongly constrains the galaxy-halo relation, both today and at high redshift. This results in detailed predictions for galaxy assembly histories and for the gravitational arena in which galaxies live. Dark halos are not expected to be passive or symmetric but to have a rich and continually evolving structure which will drive evolution in the central galaxy over its full life, exciting warps, spiral patterns and tidal arms, thickening disks, producing rings, bars and bulges. Their growth is closely related to the provision of new gas for galaxy building.

  17. Large-scale assembly bias of dark matter halos

    Science.gov (United States)

    Lazeyras, Titouan; Musso, Marcello; Schmidt, Fabian

    2017-03-01

    We present precise measurements of the assembly bias of dark matter halos, i.e. the dependence of halo bias on other properties than the mass, using curved "separate universe" N-body simulations which effectively incorporate an infinite-wavelength matter overdensity into the background density. This method measures the LIMD (local-in-matter-density) bias parameters bn in the large-scale limit. We focus on the dependence of the first two Eulerian biases bE1 and bE2 on four halo properties: the concentration, spin, mass accretion rate, and ellipticity. We quantitatively compare our results with previous works in which assembly bias was measured on fairly small scales. Despite this difference, our findings are in good agreement with previous results. We also look at the joint dependence of bias on two halo properties in addition to the mass. Finally, using the excursion set peaks model, we attempt to shed new insights on how assembly bias arises in this analytical model.

  18. Haloes and clustering in light, neutron-rich nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Orr, N.A

    2001-10-01

    Clustering is a relatively widespread phenomenon which takes on many guises across the nuclear landscape. Selected topics concerning the study of halo systems and clustering in light, neutron-rich nuclei are discussed here through illustrative examples taken from the Be isotopic chain. (author)

  19. Planetary Nebulae as kinematic and dynamical tracers of galaxy halos

    NARCIS (Netherlands)

    Coccato, Lodovico; Napolitano, Nicola; Arnaboldi, Magda; Cortesi, Arianna; Romanowsky, Aaron; Gerhard, Ortwin; Merrifield, Michael; Kuijken, Konrad; Freeman, Ken; Douglas, Nigel

    2015-01-01

    The kinematics and dynamical properties of galaxy halos are difficult to measure, given the faint stellar surface brightness that characterizes those regions. Gas-rich systems such as spiral galaxies can be probed using the radio emission of their gas component. Early type galaxies contain less gas,

  20. Uncovering the hidden iceberg structure of the Galactic halo

    Science.gov (United States)

    Moss, Vanessa A.; Di Teodoro, Enrico M.; McClure-Griffiths, Naomi M.; Lockman, Felix; Pisano, D. J.; Price, Daniel; Rees, Glen

    2018-01-01

    How the Milky Way gets its gas and keeps its measured star formation rate going are both long-standing mysteries in Galactic studies, with important implications for galaxy evolution across the Universe. I will present our recent discovery of two populations of neutral hydrogen (HI) in the halo of the Milky Way: 1) a narrow line-width dense population typical of the majority of bright high velocity cloud (HVC) components, and 2) a fainter, broad line-width diffuse population that aligns well with the population found in very sensitive pointings such as in Lockman et al. (2002). From our existing data, we concluded that the diffuse population likely outweighs the dense HI by a factor of 3. This discovery of diffuse HI, which appears to be prevalent throughout the halo, takes us closer to solving the Galactic mystery of accretion and reveals a gaseous neutral halo hidden from the view of most large-scale surveys. We are currently carrying out deep Parkes observations to investigate these results further, in order to truly uncover the nature of the diffuse HI and determine whether our 3:1 ratio (based on the limited existing data) is consistent with what is seen when Parkes and the 140 ft Green Bank telescope are employed at comparable sensitivity. With these data, through a combination of both known and new sightline measurements, we aim to reveal the structure of the Galactic halo in more detail than ever before.

  1. The reversed halo sign: update and differential diagnosis

    Science.gov (United States)

    Godoy, M C B; Viswanathan, C; Marchiori, E; Truong, M T; Benveniste, M F; Rossi, S; Marom, E M

    2012-01-01

    The reversed halo sign is characterised by a central ground-glass opacity surrounded by denser air–space consolidation in the shape of a crescent or a ring. It was first described on high-resolution CT as being specific for cryptogenic organising pneumonia. Since then, the reversed halo sign has been reported in association with a wide range of pulmonary diseases, including invasive pulmonary fungal infections, paracoccidioidomycosis, pneumocystis pneumonia, tuberculosis, community-acquired pneumonia, lymphomatoid granulomatosis, Wegener granulomatosis, lipoid pneumonia and sarcoidosis. It is also seen in pulmonary neoplasms and infarction, and following radiation therapy and radiofrequency ablation of pulmonary malignancies. In this article, we present the spectrum of neoplastic and non-neoplastic diseases that may show the reversed halo sign and offer helpful clues for assisting in the differential diagnosis. By integrating the patient's clinical history with the presence of the reversed halo sign and other accompanying radiological findings, the radiologist should be able to narrow the differential diagnosis substantially, and may be able to provide a presumptive final diagnosis, which may obviate the need for biopsy in selected cases, especially in the immunosuppressed population. PMID:22553298

  2. Alpha alpha scattering in halo effective field theory

    NARCIS (Netherlands)

    Higa, R.; Hammer, H. -W.; van Kolck, U.

    2008-01-01

    We study the two-alpha-particle (alpha alpha) system in an Effective Field Theory (EFT) for halo-like systems. We propose a power Counting that incorporates the subtle interplay of strong and electromagnetic forces leading to a narrow resonance at an energy of about 0.1 MeV. We investigate the EFT

  3. Matting of Hair Due to Halo-egg Shampoo

    Directory of Open Access Journals (Sweden)

    Z M Mani

    1983-01-01

    Full Text Available A case of hair matting in an 18 year old female is reported. The hair got densely entangled immediately after washing the hair with ′Halo Egg′ shampoo. The hair was disentangled completely after prolonged dipping of the hair in arachis oil frr 5 days.

  4. A galaxy-halo model for multiple cosmological tracers

    Science.gov (United States)

    Bull, Philip

    2017-10-01

    The information extracted from large galaxy surveys with the likes of DES, DESI, Euclid, LSST, SKA, and WFIRST will be greatly enhanced if the resultant galaxy catalogues can be cross-correlated with one another. Predicting the nature of the information gain, and developing the tools to realize it, depends on establishing a consistent model of how the galaxies detected by each survey trace the same underlying matter distribution. Existing analytic methods, such as halo occupation distribution modelling, are not well suited for this task, and can suffer from ambiguities and tuning issues when applied to multiple tracers. In this paper, we take the first step towards constructing an alternative that provides a common model for the connection between galaxies and dark matter haloes across a wide range of wavelengths (and thus tracer populations). This is based on a chain of parametrized statistical distributions that model the connection between (I) halo mass and bulk physical properties of galaxies, such as star formation rate; and (II) those same physical properties and a variety of emission processes. The result is a flexible parametric model that allows analytic halo model calculations of one-point functions to be carried out for multiple tracers, as well as providing semi realistic galaxy properties for fast mock catalogue generation.

  5. Giant Radio Halos in Galaxy Clusters as Probes of Particle ...

    Indian Academy of Sciences (India)

    Giant radio halos in galaxy clusters probe mechanisms of particle acceleration connected with cluster merger events. Shocks and turbulence are driven in the inter-galactic medium (IGM) during clusters mergers and may have a deep impact on the non-thermal properties of galaxy clusters. Models of turbulent ...

  6. Inheritance of halo blight resistance in common bean | Chataika ...

    African Journals Online (AJOL)

    Halo blight caused by (Pseudomonas syringe pv. phaseolicola (Burkh) (Psp)) is an important disease of common bean (Phaseolus vulgaris L.) world-wide. Several races of the Psp exist and likewise some sources of resistance in common bean have been identified. CAL 143, is a CIAT-bred common bean line, which was ...

  7. DM haloes in the fifth-force cosmology

    NARCIS (Netherlands)

    Hellwing, Wojciech A.; Cautun, Marius; Knebe, Alexander; Juszkiewicz, Roman; Knollmann, Steffen

    2013-01-01

    We investigate how long-range scalar interactions affect the properties of dark matter haloes. For doing so we employ the ReBEL model which implements an additional interaction between dark matter particles. On the phenomenological level this is equivalent to a modification of gravity. We analyse

  8. Prospects for detecting supersymmetric dark matter in the Galactic halo.

    Science.gov (United States)

    Springel, V; White, S D M; Frenk, C S; Navarro, J F; Jenkins, A; Vogelsberger, M; Wang, J; Ludlow, A; Helmi, A

    2008-11-06

    Dark matter is the dominant form of matter in the Universe, but its nature is unknown. It is plausibly an elementary particle, perhaps the lightest supersymmetric partner of known particle species. In this case, annihilation of dark matter in the halo of the Milky Way should produce gamma-rays at a level that may soon be observable. Previous work has argued that the annihilation signal will be dominated by emission from very small clumps (perhaps smaller even than the Earth), which would be most easily detected where they cluster together in the dark matter haloes of dwarf satellite galaxies. Here we report that such small-scale structure will, in fact, have a negligible impact on dark matter detectability. Rather, the dominant and probably most easily detectable signal will be produced by diffuse dark matter in the main halo of the Milky Way. If the main halo is strongly detected, then small dark matter clumps should also be visible, but may well contain no stars, thereby confirming a key prediction of the cold dark matter model.

  9. Is the halo responsible for the microlensing events?

    CERN Document Server

    Roulet, E.; Giudice, G.F.

    1994-01-01

    Abstract: We discuss whether the astrophysical objects responsible for the recently reported microlensing events of sources in the Large Magellanic Cloud can be identified as the brown dwarf components of the spheroid of our galaxy, rather than the constituents of a dark baryonic halo.

  10. Lensing effects of misaligned disks in dark matter halos

    NARCIS (Netherlands)

    Quadri, R.; Möller, O.; Natarajan, P.

    2002-01-01

    Published in: Astrophys. J. 597 (2003) 659-671 citations recorded in [Science Citation Index] Abstract: We study the observational signatures of the lensing signal produced by dark matter halos with embedded misaligned disks. This issue is of particular interest at the present time since most of the

  11. Spin alignment of dark matter haloes in filaments and walls

    NARCIS (Netherlands)

    Aragón-Calvo, M. A.; Weygaert, R. van de; Jones, B. J. T.; Hulst, T. van der

    2006-01-01

    Abstract: The MMF technique is used to segment the cosmic web as seen in a cosmological N-body simulation into wall-like and filament-like structures. We find that the spins and shapes of dark matter haloes are significantly correlated with each other and with the orientation of their host

  12. Spin alignment of dark matter halos in filaments and walls

    NARCIS (Netherlands)

    Aragon-Calvo, Miguel A.; van de Weygaert, Rien; Jones, Bernard J. T.; van der Hulst, J. M.

    2007-01-01

    The MMF technique is used to segment the cosmic web as seen in a cosmological N-body simulation into wall-like and filament-like structures. We find that the spins and shapes of dark matter halos are significantly correlated with each other and with the orientation of their host structures. The

  13. Fast weak-lensing simulations with halo model

    Science.gov (United States)

    Giocoli, Carlo; Di Meo, Sandra; Meneghetti, Massimo; Jullo, Eric; de la Torre, Sylvain; Moscardini, Lauro; Baldi, Marco; Mazzotta, Pasquale; Metcalf, R. Benton

    2017-09-01

    Full ray-tracing maps of gravitational lensing, constructed from N-body simulations, represent a fundamental tool to interpret present and future weak-lensing data. However, the limitation of computational resources and storage capabilities severely restricts the number of realizations that can be performed in order to accurately sample both the cosmic shear models and covariance matrices. In this paper, we present a halo model formalism for weak gravitational lensing that alleviates these issues by producing weak-lensing mocks at a reduced computational cost. Our model takes as input the halo population within a desired light cone and the linear power spectrum of the underlined cosmological model. We examine the contribution given by the presence of substructures within haloes to the cosmic shear power spectrum and quantify it to the percent level. Our method allows us to reconstruct high-resolution convergence maps, for any desired source redshifts, of light cones that realistically trace the matter density distribution in the universe, account for masked area and sample selections. We compare our analysis on the same large-scale structures constructed using ray-tracing techniques and find very good agreements in both the linear and non-linear regimes up to few percent levels. The accuracy and speed of our method demonstrate the potential of our halo model for weak-lensing statistics and the possibility to generate a large sample of convergence maps for different cosmological models as needed for the analysis of large galaxy redshift surveys.

  14. Giant Radio Halos in Galaxy Clusters as Probes of Particle ...

    Indian Academy of Sciences (India)

    Abstract. Giant radio halos in galaxy clusters probe mechanisms of particle acceleration connected with cluster merger events. Shocks and turbulence are driven in the inter-galactic medium (IGM) during clusters mergers and may have a deep impact on the non-thermal properties of galaxy clusters. Models of turbulent ...

  15. Cosmic Rays in the Disk and Halo of Galaxies

    Science.gov (United States)

    Dogiel, V. A.; Breitschwerdt, D.

    2012-09-01

    We give a review of cosmic ray propagation models. It is shown that the development of the theory of cosmic ray origin leads inevitably to the conclusion that cosmic ray propagation in the Galaxy is determined by effective particle scattering, which is described by spatial diffusion. The Galactic Disk is surrounded by an extended halo, in which cosmic rays are confined before escaping into intergalactic space. For a long time cosmic ray convective outflow from the Galaxy (galactic wind) was believed to be insignificant. However, investigations of hydrodynamic stability and an analysis of ISM dynamics (including cosmic rays) showed that a galactic wind was emanating near the disk, and accelerating towards the halo, reaching its maximum velocity far away from the disk. Therefore convective cosmic ray transport should be important in galactic halos. Recent analysis of the gamma-ray emissivity in the Galactic disk of EGRET data, which showed that cosmic rays are more or less uniformly distributed in the radial direction of the disk, as well as the interpretation of soft X-ray emission in galactic halos, give convincing evidence of the existence of a galactic wind in star forming galaxies.

  16. The deleuzian abstract machines

    DEFF Research Database (Denmark)

    Werner Petersen, Erik

    2005-01-01

    To most people the concept of abstract machines is connected to the name of Alan Turing and the development of the modern computer. The Turing machine is universal, axiomatic and symbolic (E.g. operating on symbols). Inspired by Foucault, Deleuze and Guattari extended the concept of abstract...... machines to singular, non-axiomatic and diagrammatic machines. That is: Machines which constitute becomings. This presentation gives a survey of the development of the concept of abstract machines in the philosophy of Deleuze and Guatari and the function of these abstract machines in the creation of works...... of art. From Difference and Repetition to Anti-Oedipus, the machines are conceived as binary machines based on the exclusive or inclusive use respectively of the three syntheses: conexa, disjuncta and conjuncta. The machines have a twofold embedment: In the desiring-production and in the social...

  17. Electronics and Calibration system for the CMS Beam Halo Monitor

    CERN Document Server

    Tosi, Nicolò; Fabbri, Franco L; Finkel, Alexey; Orfanelli, Stella; Loos, R; Montanari, Alessandro; Rusack, R; Stickland, David P

    2014-01-01

    In the context of increasing luminosity of LHC, it will be important to accurately measure the Machine Induced Background. A new monitoring system will be installed in the cavern of the Compact Muon Solenoid (CMS) experiment for measuring the beam background at high radius. This detector is composed of synthetic quartz Cherenkov radiators, coupled to fast photomultiplier tubes (PMT). The readout chain of this detector will make use of many components developed for the Phase 1 upgrade to the CMS Hadron Calorimeter electronics, with a dedicated firmware and readout adapted to the beam monitoring requirements. The PMT signal will be digitized by a charge integrating ASIC (QIE10), providing both the signal rise time and the charge integrated over one bunch crossing. The backend electronics will record bunch-by-bunch histograms, which will be published to CMS and the LHC using the newly designed CMS beam instrumentation specific DAQ. A calibration monitoring system has been designed to generate triggered pulses of...

  18. The halo sign: HRCT findings in 85 patients.

    Science.gov (United States)

    Alves, Giordano Rafael Tronco; Marchiori, Edson; Irion, Klaus; Nin, Carlos Schuler; Watte, Guilherme; Pasqualotto, Alessandro Comarú; Severo, Luiz Carlos; Hochhegger, Bruno

    2016-01-01

    The halo sign consists of an area of ground-glass opacity surrounding pulmonary lesions on chest CT scans. We compared immunocompetent and immunosuppressed patients in terms of halo sign features and sought to identify those of greatest diagnostic value. This was a retrospective study of CT scans performed at any of seven centers between January of 2011 and May of 2015. Patients were classified according to their immune status. Two thoracic radiologists reviewed the scans in order to determine the number of lesions, as well as their distribution, size, and contour, together with halo thickness and any other associated findings. Of the 85 patients evaluated, 53 were immunocompetent and 32 were immunosuppressed. Of the 53 immunocompetent patients, 34 (64%) were diagnosed with primary neoplasm. Of the 32 immunosuppressed patients, 25 (78%) were diagnosed with aspergillosis. Multiple and randomly distributed lesions were more common in the immunosuppressed patients than in the immunocompetent patients (p Pacientes imunocompetentes e imunodeprimidos foram comparados quanto a características do sinal do halo a fim de identificar as de maior valor diagnóstico. Estudo retrospectivo de tomografias realizadas em sete centros entre janeiro de 2011 e maio de 2015. Os pacientes foram classificados de acordo com seu estado imunológico. Dois radiologistas torácicos analisaram os exames a fim de determinar o número de lesões e sua distribuição, tamanho e contorno, bem como a espessura do halo e quaisquer outros achados associados. Dos 85 pacientes avaliados, 53 eram imunocompetentes e 32 eram imunodeprimidos. Dos 53 pacientes imunocompetentes, 34 (64%) receberam diagnóstico de neoplasia primária. Dos 32 pacientes imunodeprimidos, 25 (78%) receberam diagnóstico de aspergilose. Lesões múltiplas e distribuídas aleatoriamente foram mais comuns nos imunodeprimidos do que nos imunocompetentes (p pacientes imunocompetentes são bastante diferentes das observadas em

  19. Galaxy Mergers and Dark Matter Halo Mergers in LCDM: Mass, Redshift, and Mass-Ratio Dependence

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, Kyle R.; Bullock, James S.; Barton, Elizabeth J.; /UC, Irvine; Wechsler, Risa H.; /KIPAC, Menlo Park /SLAC

    2009-08-03

    We employ a high-resolution LCDM N-body simulation to present merger rate predictions for dark matter halos and investigate how common merger-related observables for galaxies - such as close pair counts, starburst counts, and the morphologically disturbed fraction - likely scale with luminosity, stellar mass, merger mass ratio, and redshift from z = 0 to z = 4. We provide a simple 'universal' fitting formula that describes our derived merger rates for dark matter halos a function of dark halo mass, merger mass ratio, and redshift, and go on to predict galaxy merger rates using number density-matching to associate halos with galaxies. For example, we find that the instantaneous merger rate of m/M > 0.3 mass ratio events into typical L {approx}> fL{sub *} galaxies follows the simple relation dN/dt {approx_equal} 0.03(1+f)Gyr{sup -1} (1+z){sup 2.1}. Despite the rapid increase in merger rate with redshift, only a small fraction of > 0.4L{sub *} high-redshift galaxies ({approx} 3% at z = 2) should have experienced a major merger (m/M > 0.3) in the very recent past (t < 100 Myr). This suggests that short-lived, merger-induced bursts of star formation should not contribute significantly to the global star formation rate at early times, in agreement with observational indications. In contrast, a fairly high fraction ({approx} 20%) of those z = 2 galaxies should have experienced a morphologically transformative merger within a virial dynamical time. We compare our results to observational merger rate estimates from both morphological indicators and pair-fraction based determinations between z = 0-2 and show that they are consistent with our predictions. However, we emphasize that great care must be made in these comparisons because the predicted observables depend very sensitively on galaxy luminosity, redshift, overall mass ratio, and uncertain relaxation timescales for merger remnants. We show that the majority of bright galaxies at z = 3 should have undergone a

  20. Constraints on the Formation of M31’s Stellar Halo from the SPLASH Survey

    Directory of Open Access Journals (Sweden)

    Karoline Gilbert

    2017-09-01

    Full Text Available The SPLASH (Spectroscopic and Photometric Landscape of Andromeda’s Stellar Halo Survey has observed fields throughout M31’s stellar halo, dwarf satellites, and stellar disk. The observations and derived measurements have either been compared to predictions from simulations of stellar halo formation or modeled directly in order to derive inferences about the formation and evolution of M31’s stellar halo. We summarize some of the major results from the SPLASH survey and the resulting implications for our understanding of the build-up of M31’s stellar halo.

  1. A Phenomenological Model of Star Formation Efficiency in Dark Matter Halos

    Science.gov (United States)

    Finnegan, Daniel; Alsheshakly, Ghadeer; Moustakas, John

    2018-01-01

    The efficiency of star formation in massive dark matter halos is extraordinarily low, less than 10% in >10^13 Msun sized halos. Although many physical processes have been proposed to explain this low efficiency, such as feedback from supermassive black halos and massive stars, this question remains one of the most important outstanding problems in galaxy evolution. To explore this problem, we build a simple phenomenological model to predict the variations in gas fraction and star formation efficiency as a function of halo mass. We compare our model predictions to central galaxy stellar masses and halo masses drawn from the literature, and discuss plans for our future work.

  2. Halo-independent determination of the unmodulated WIMP signal in DAMA: the isotropic case

    Science.gov (United States)

    Gondolo, Paolo; Scopel, Stefano

    2017-09-01

    We present a halo-independent determination of the unmodulated signal corresponding to the DAMA modulation if interpreted as due to dark matter weakly interacting massive particles (WIMPs). First we show how a modulated signal gives information on the WIMP velocity distribution function in the Galactic rest frame from which the unmodulated signal descends. Then we describe a mathematically-sound profile likelihood analysis in which the likelihood is profiled over a continuum of nuisance parameters (namely, the WIMP velocity distribution). As a first application of the method, which is very general and valid for any class of velocity distributions, we restrict the analysis to velocity distributions that are isotropic in the Galactic frame. In this way we obtain halo-independent maximum-likelihood estimates and confidence intervals for the DAMA unmodulated signal. We find that the estimated unmodulated signal is in line with expectations for a WIMP-induced modulation and is compatible with the DAMA background+signal rate. Specifically, for the isotropic case we find that the modulated amplitude ranges between a few percent and about 25% of the unmodulated amplitude, depending on the WIMP mass.

  3. ZOMG - III. The effect of halo assembly on the satellite population

    Science.gov (United States)

    Garaldi, Enrico; Romano-Díaz, Emilio; Borzyszkowski, Mikolaj; Porciani, Cristiano

    2018-01-01

    We use zoom hydrodynamical simulations to investigate the properties of satellites within galaxy-sized dark-matter haloes with different assembly histories. We consider two classes of haloes at redshift z = 0: 'stalled' haloes that assembled at z > 1 and 'accreting' ones that are still forming nowadays. Previously, we showed that the stalled haloes are embedded within thick filaments of the cosmic web, while the accreting ones lie where multiple thin filaments converge. We find that satellites in the two classes have both similar and different properties. Their mass spectra, radial count profiles, baryonic and stellar content, and the amount of material they shed are indistinguishable. However, the mass fraction locked in satellites is substantially larger for the accreting haloes as they experience more mergers at late times. The largest difference is found in the satellite kinematics. Substructures fall towards the accreting haloes along quasi-radial trajectories whereas an important tangential velocity component is developed, before accretion, while orbiting the filament that surrounds the stalled haloes. Thus, the velocity anisotropy parameter of the satellites (β) is positive for the accreting haloes and negative for the stalled ones. This signature enables us to tentatively categorize the Milky Way halo as stalled based on a recent measurement of β. Half of our haloes contain clusters of satellites with aligned orbital angular momenta corresponding to flattened structures in space. These features are not driven by baryonic physics and are only found in haloes hosting grand-design spiral galaxies, independently of their assembly history.

  4. Detection of Hot Halo Gets Theory Out of Hot Water

    Science.gov (United States)

    2006-02-01

    Scientists using NASA's Chandra X-ray Observatory have detected an extensive halo of hot gas around a quiescent spiral galaxy. This discovery is evidence that galaxies like our Milky Way are still accumulating matter from the gradual inflow of intergalactic gas. "What we are likely witnessing here is the ongoing galaxy formation process," said Kristian Pedersen of the University of Copenhagen, Denmark, and lead author of a report on the discovery. Chandra observations show that the hot halo extends more than 60,000 light years on either side of the disk of the galaxy known as NGC 5746. The detection of such a large halo alleviates a long-standing problem for the theory of galaxy formation. Spiral galaxies are thought to form from enormous clouds of intergalactic gas that collapse to form giant, spinning disks of stars and gas. Chandra X-ray Image of NGC 5746 Chandra X-ray Image of NGC 5746 One prediction of this theory is that large spiral galaxies should be immersed in halos of hot gas left over from the galaxy formation process. Hot gas has been detected around spiral galaxies in which vigorous star formation is ejecting matter from the galaxy, but until now hot halos due to infall of intergalactic matter have not been detected. "Our observations solve the mystery of the missing hot halos around spiral galaxies," said Pedersen. "The halos exist, but are so faint that an extremely sensitive telescope such as Chandra is needed to detect them." DSS Optical Image of NGC 5746 DSS Optical Image of NGC 5746 NGC 5746 is a massive spiral galaxy about a 100 million light years from Earth. Its disk of stars and gas is viewed almost edge-on. The galaxy shows no signs of unusual star formation, or energetic activity from its nuclear region, making it unlikely that the hot halo is produced by gas flowing out of the galaxy. "We targeted NGC 5746 because we thought its distance and orientation would give us the best chance to detect a hot halo caused by the infall of

  5. Machine tool structures

    CERN Document Server

    Koenigsberger, F

    1970-01-01

    Machine Tool Structures, Volume 1 deals with fundamental theories and calculation methods for machine tool structures. Experimental investigations into stiffness are discussed, along with the application of the results to the design of machine tool structures. Topics covered range from static and dynamic stiffness to chatter in metal cutting, stability in machine tools, and deformations of machine tool structures. This volume is divided into three sections and opens with a discussion on stiffness specifications and the effect of stiffness on the behavior of the machine under forced vibration c

  6. HTS machine laboratory prototype

    DEFF Research Database (Denmark)

    High Temperature Superconducting (HTS) electrical machines have the potential to offer outstanding technical performance with regards to efficiency and power density. However, the industry needs to address a large number of challenges in the attempt to harvest the full potential of HTS machines...... machine. The machine comprises six stationary HTS field windings wound from both YBCO and BiSCOO tape operated at liquid nitrogen temperature and enclosed in a cryostat, and a three phase armature winding spinning at up to 300 rpm. This design has full functionality of HTS synchronous machines. The design...... details and experimental results are shown together with discussions about their implication for scaled up HTS machines....

  7. Halo histories versus Galaxy properties at z = 0 - I. The quenching of star formation

    Science.gov (United States)

    Tinker, Jeremy L.; Wetzel, Andrew R.; Conroy, Charlie; Mao, Yao-Yuan

    2017-12-01

    We test whether halo age and galaxy age are correlated at fixed halo and galaxy mass. The formation histories, and thus ages, of dark matter haloes correlate with their large-scale density ρ, an effect known as assembly bias. We test whether this correlation extends to galaxies by measuring the dependence of galaxy stellar age on ρ. To clarify the comparison between theory and observation, and to remove the strong environmental effects on satellites, we use galaxy group catalogues to identify central galaxies and measure their quenched fraction, fQ, as a function of large-scale environment. Models that match halo age to central galaxy age predict a strong positive correlation between fQ and ρ. However, we show that the amplitude of this effect depends on the definition of halo age: assembly bias is significantly reduced when removing the effects of splashback haloes - those haloes that are central but have passed through a larger halo or experienced strong tidal encounters. Defining age using halo mass at its peak value rather than current mass removes these effects. In Sloan Digital Sky Survey data, at M* ≳ 1010 M⊙ h-2, there is a ∼5 per cent increase in fQ from low-to-high densities, which is in agreement with predictions of dark matter haloes using peak halo mass. At lower stellar mass there is little to no correlation of fQ with ρ. For these galaxies, age matching is inconsistent with the data across the range of halo formation metrics that we tested. This implies that halo formation history has a small but statistically significant impact on quenching of star formation at high masses, while the quenching process in low-mass central galaxies is uncorrelated with halo formation history.

  8. Moving-mesh cosmology: characteristics of galaxies and haloes

    Science.gov (United States)

    Kereš, Dušan; Vogelsberger, Mark; Sijacki, Debora; Springel, Volker; Hernquist, Lars

    2012-09-01

    We discuss cosmological hydrodynamic simulations of galaxy formation performed with the new moving-mesh code AREPO, which promises higher accuracy compared with the traditional smoothed particle hydrodynamics (SPH) technique that has been widely employed for this problem. In this exploratory study, we deliberately limit the complexity of the physical processes followed by the code for ease of comparison with previous calculations, and include only cooling of gas with a primordial composition, heating by a spatially uniform ultraviolet background, and a simple subresolution model for regulating star formation in the dense interstellar medium. We use an identical set of physics in corresponding simulations carried out with the well-tested SPH code GADGET, adopting also the same high-resolution gravity solver. We are thus able to compare both simulation sets on an object-by-object basis, allowing us to cleanly isolate the impact of different hydrodynamical methods on galaxy and halo properties. In accompanying papers, Vogelsberger et al. and Sijacki et al., we focus on an analysis of the global baryonic statistics predicted by the simulation codes, and complementary idealized simulations that highlight the differences between the hydrodynamical schemes. Here we investigate their influence on the baryonic properties of simulated galaxies and their surrounding haloes. We find that AREPO leads to significantly higher star formation rates for galaxies in massive haloes and to more extended gaseous discs in galaxies, which also feature a thinner and smoother morphology than their GADGET counterparts. Consequently, galaxies formed in AREPO have larger sizes and higher specific angular momentum than their SPH correspondents. Interestingly, the more efficient cooling flows in AREPO yield higher densities and lower entropies in halo centres compared to GADGET, whereas the opposite trend is found in halo outskirts. The cooling differences leading to higher star formation rates

  9. Learning Change from Synthetic Aperture Radar Images: Performance Evaluation of a Support Vector Machine to Detect Earthquake and Tsunami-Induced Changes

    Directory of Open Access Journals (Sweden)

    Marc Wieland

    2016-09-01

    Full Text Available This study evaluates the performance of a Support Vector Machine (SVM classifier to learn and detect changes in single- and multi-temporal X- and L-band Synthetic Aperture Radar (SAR images under varying conditions. The purpose is to provide guidance on how to train a powerful learning machine for change detection in SAR images and to contribute to a better understanding of potentials and limitations of supervised change detection approaches. This becomes particularly important on the background of a rapidly growing demand for SAR change detection to support rapid situation awareness in case of natural disasters. The application environment of this study thus focuses on detecting changes caused by the 2011 Tohoku earthquake and tsunami disaster, where single polarized TerraSAR-X and ALOS PALSAR intensity images are used as input. An unprecedented reference dataset of more than 18,000 buildings that have been visually inspected by local authorities for damages after the disaster forms a solid statistical population for the performance experiments. Several critical choices commonly made during the training stage of a learning machine are being assessed for their influence on the change detection performance, including sampling approach, location and number of training samples, classification scheme, change feature space and the acquisition dates of the satellite images. Furthermore, the proposed machine learning approach is compared with the widely used change image thresholding. The study concludes that a well-trained and tuned SVM can provide highly accurate change detections that outperform change image thresholding. While good performance is achieved in the binary change detection case, a distinction between multiple change classes in terms of damage grades leads to poor performance in the tested experimental setting. The major drawback of a machine learning approach is related to the high costs of training. The outcomes of this study, however

  10. Reactive Turing machines

    National Research Council Canada - National Science Library

    Baeten, Jos; Luttik, Bas; Tilburg, P.J.A

    2013-01-01

    textabstractWe propose reactive Turing machines (RTMs), extending classical Turing machines with a process-theoretical notion of interaction, and use it to define a notion of executable transition system...

  11. Machining with abrasives

    CERN Document Server

    Jackson, Mark J

    2011-01-01

    Abrasive machining is key to obtaining the desired geometry and surface quality in manufacturing. This book discusses the fundamentals and advances in the abrasive machining processes. It provides a complete overview of developing areas in the field.

  12. Applied machining technology

    CERN Document Server

    Tschätsch, Heinz

    2010-01-01

    Machining and cutting technologies are still crucial for many manufacturing processes. This reference presents all important machining processes in a comprehensive and coherent way. It includes many examples of concrete calculations, problems and solutions.

  13. Machine medical ethics

    CERN Document Server

    Pontier, Matthijs

    2015-01-01

    The essays in this book, written by researchers from both humanities and sciences, describe various theoretical and experimental approaches to adding medical ethics to a machine in medical settings. Medical machines are in close proximity with human beings, and getting closer: with patients who are in vulnerable states of health, who have disabilities of various kinds, with the very young or very old, and with medical professionals. In such contexts, machines are undertaking important medical tasks that require emotional sensitivity, knowledge of medical codes, human dignity, and privacy. As machine technology advances, ethical concerns become more urgent: should medical machines be programmed to follow a code of medical ethics? What theory or theories should constrain medical machine conduct? What design features are required? Should machines share responsibility with humans for the ethical consequences of medical actions? How ought clinical relationships involving machines to be modeled? Is a capacity for e...

  14. Brain versus Machine Control.

    Directory of Open Access Journals (Sweden)

    Jose M Carmena

    2004-12-01

    Full Text Available Dr. Octopus, the villain of the movie "Spiderman 2", is a fusion of man and machine. Neuroscientist Jose Carmena examines the facts behind this fictional account of a brain- machine interface

  15. Tube Alinement for Machining

    Science.gov (United States)

    Garcia, J.

    1984-01-01

    Tool with stepped shoulders alines tubes for machining in preparation for welding. Alinement with machine tool axis accurate to within 5 mils (0.13mm) and completed much faster than visual setup by machinist.

  16. Proton halos in the 1 s0 d shell

    Science.gov (United States)

    Brown, B. A.; Hansen, P. G.

    1996-02-01

    The shell-model properties of proton halo states in proton-rich 1 s0 d shell nuclei are investigated. The most interesting cases appear to be those in 26,27P and 27S. The parallel-momentum distributions of core fragments from proton stripping reactions may provide experimental insight into the structure of the halo states and the role played by the reaction mechanism. The “generalized Coulomb shift”, defined as the difference between the neutron and proton separation energies for an analogue pair, is shown to vary smoothly as a function of proton-separation energy and provides a good tool for mass extrapolations. The relation between the total interaction cross section and the matter radius is discussed.

  17. Galactic Halo Wormhole Solutions in f(T Gravity

    Directory of Open Access Journals (Sweden)

    M. Sharif

    2014-01-01

    Full Text Available The proposal of galactic halo region is based on the idea that dark halos contain some characteristics needed to support traversable wormhole solutions. We explore wormhole solutions in this region in the framework of generalized teleparallel gravity. We consider static spherically symmetric wormhole spacetime with flat galactic rotational curves and obtain expressions of matter components for nondiagonal tetrad. The effective energy-momentum tensor leads to the violation of energy conditions which may impose condition on the normal matter to satisfy these conditions. We take two well-known f(T models in exponential and logarithmic forms to discuss wormhole solutions as well as the equilibrium condition. It is concluded that wormhole solutions violating weak energy condition are obtained for both models with stable configuration.

  18. Two distinct halo populations in the solar neighborhood. III

    DEFF Research Database (Denmark)

    Schuster, W. J.; Moreno, E.; Nissen, Poul Erik

    2012-01-01

    Context. In Papers I and II of this series, we have found clear indications of the existence of two distinct populations of stars in the solar neighborhood belonging to the metal-rich end of the halo metallicity distribution function. Based on high-resolution, high S/N spectra, it is possible...... to distinguish between “high-alpha” and “low-alpha” components using the [α/Fe] versus [Fe/H] diagram. Aims. Precise relative ages and orbital parameters are determined for 67 halo and 16 thick-disk stars having metallicities in the range −1.4 ... populations in the formation and evolution of the Galaxy. Methods. Ages are derived by comparing the positions of stars in the log Teff–log g diagram with isochrones from the Y2 models interpolated to the exact [Fe/H] and [α/Fe] values of each star. The stellar parameters have been adopted from the preceding...

  19. Relativistic Hartree-Bogoliubov description of the halo nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Meng, J.; Ring, P. [Universitaet Muenchen, Garching (Germany)

    1996-12-31

    Here the authors report the development of the relativistic Hartree-Bogoliubov theory in coordinate space. Pairing correlations are taken into account by both density dependent force of zero range and finite range Gogny force. As a primary application the relativistic HB theory is used to describe the chain of Lithium isotopes reaching from {sup 6}Li to {sup 11}Li. In contrast to earlier investigations within a relativistic mean field theory and a density dependent Hartree Fock theory, where the halo in {sup 11}Li could only be reproduced by an artificial shift of the 1p{sub 1/2} level close to the continuum limit, the halo is now reproduced in a self-consistent way without further modifications using the scattering of Cooper pairs to the 2s{sub 1/2} level in the continuum. Excellent agreement with recent experimental data is observed.

  20. The abundance of boron in three halo stars

    Science.gov (United States)

    Duncan, Douglas K.; Lambert, David L.; Lemke, Michael

    1992-01-01

    B abundances for three halo stars: HD 140283, HD 19445, and HD 201891 are presented. Using recent determinations of the Be abundance in HD 140283, B/Be of 10 +5/-4 is found for this star, and similar ratios are inferred for HD 19445 and HD 201891. This ratio is equal to the minimum value of 10 expected from a synthesis of B and Be by high-energy cosmic-ray spallation reactions in the interstellar medium. It is shown that the accompanying synthesis of Li by alpha on alpha fusion reactions is probably a minor contributor to the observed 'primordial' Li of halo stars. The observed constant ratios of B/O and Be/O are expected if the principal channel of synthesis involves cosmic-ray CNO nuclei from the supernovae colliding with interstellar protons.

  1. Toward a combined SAGE II-HALOE aerosol climatology: an evaluation of HALOE version 19 stratospheric aerosol extinction coefficient observations

    Directory of Open Access Journals (Sweden)

    L. W. Thomason

    2012-09-01

    Full Text Available Herein, the Halogen Occultation Experiment (HALOE aerosol extinction coefficient data is evaluated in the low aerosol loading period after 1996 as the first necessary step in a process that will eventually allow the production of a combined HALOE/SAGE II (Stratospheric Aerosol and Gas Experiment aerosol climatology of derived aerosol products including surface area density. Based on these analyses, it is demonstrated that HALOE's 3.46 μm is of good quality above 19 km and suitable for scientific applications above that altitude. However, it is increasingly suspect at lower altitudes and should not be used below 17 km under any circumstances after 1996. The 3.40 μm is biased by about 10% throughout the lower stratosphere due to the failure to clear NO2 but otherwise appears to be a high quality product down to 15 km. The 2.45 and 5.26 μm aerosol extinction coefficient measurements are clearly biased and should not be used for scientific applications after the most intense parts of the Pinatubo period. Many of the issues in the aerosol data appear to be related to either the failure to clear some interfering gas species or doing so poorly. For instance, it is clear that the 3.40 μm aerosol extinction coefficient measurements can be improved through the inclusion of an NO2 correction and could, in fact, end up as the highest quality overall HALOE aerosol extinction coefficient measurement. It also appears that the 2.45 and 5.26 μm channels may be improved by updating the Upper Atmosphere Pilot Database which is used as a resource for the removal of gas species otherwise not available from direct HALOE measurements. Finally, a simple model to demonstrate the promise of mixed visible/infrared aerosol extinction coefficient ensembles for the retrieval of bulk aerosol properties demonstrates that a combined HALOE/SAGE II aerosol climatology is feasible and may represent a substantial improvement over independently derived

  2. Are the supergiant halos experimental evidence for the pionic radioactivity?

    Science.gov (United States)

    Ion, D. B.; Ion-Mihai, R.

    1994-10-01

    Pionic radiohalos (PIRH), as an integral time record of the pionic nuclear radioactivity of the heavy nuclides with Z > 80 from the inclusions from ancient minerals, are introduced. It is then shown that the essential characteristic features of the observed supergiant halos (SGH) are reproduced with a surprisingly high accuracy by those of the pionic radiohalos. For the clarification of this problem new experimental investigations including pionic detection methods are suggested.

  3. Mapping Milky Way Halo Structure with Blue Horizontal Branch Stars

    Science.gov (United States)

    Martin, Charles; Newberg, Heidi Jo; Carlin, Jeffrey L.

    2017-01-01

    The use of blue horizontal brach (BHB) and red giant branch stars as tracers of stellar debris streams is a common practice and has been useful in the confirmation of kinematic properties of previously identified streams. This work explores less common ways of untangling the velocity signatures of streams traveling radially to our line of sight, and to peer toward the higher density region of the Galactic Center using data from the Sloan Digital Sky Survey (SDSS). Using spectra of BHB stars, we are able to kinematically distinguish moving groups in the Milky Way halo. The results of this thesis advance our knowledge of the following stellar halo substructures: the Pisces Stellar Stream, the Hercules-Aquila Cloud, the Hercules Halo Stream, and the Hermus Stream. A study of red giant stars led to the kinematic discovery of the Pisces Stellar Stream. Red giant stars were also examined to determine that the previously identified velocity signature that was suggested for the Hercules-Aquila Cloud was due to disk star contamination and errors in preliminary SDSS velocities. The Hercules Halo Stream is a previously unidentified structure that could be related to the Hercules-Aquila Cloud, and was discovered as a velocity excess of SDSS BHB stars. We identify a group of 10 stars with similar velocities that are spatially coincident with the Hermus Stream. An orbit is fit to the Hermus Stream that rules out a connection with the Phoenix Stream.This work was supported by NSF grants AST 09-37523, 14-09421, 16-15688, the NASA/NY Space Grant fellowship, and contributions made by The Marvin Clan, Babette Josephs, Manit Limlamai, and the 2015 Crowd Funding Campaign to Support Milky Way Research.

  4. The Connection between Radio Halos and Cluster Mergers and the ...

    Indian Academy of Sciences (India)

    and the Statistical Properties of the Radio Halo Population. R. Cassano1,2,∗. , G. Brunetti2 & T. ... sources located in the cluster central regions, with spatial extent similar to that of the hot ICM and steep radio spectra, α > 1.1 ... distribution of clusters in the P1.4 − LX diagram (Brunetti et al. 2007): RH trace the well-known ...

  5. Can $\\beta$-decay probe excited state halos?

    CERN Multimedia

    2002-01-01

    In the first experiment at the newly constructed ISOLDE Facility the first-forbidden $\\beta$-decay of $^{17}$Ne into the first excited state of $^{17}$F has been measured. It is a factor two faster than the corresponding mirror decay and thus gives one of the largest recorded asymmetries for $\\beta$-decays feeding bound final states. Shell-model calculations can only reproduce the asymmetry if the halo structure of the $^{17}$F state is taken into account.

  6. The Effects of Varying Cosmological Parameters on Halo Substructure

    Science.gov (United States)

    Dooley, Gregory A.; Griffen, Brendan F.; Zukin, Phillip; Ji, Alexander P.; Vogelsberger, Mark; Hernquist, Lars E.; Frebel, Anna

    2014-05-01

    We investigate how different cosmological parameters, such as those delivered by the WMAP and Planck missions, affect the nature and evolution of the dark matter halo substructure. We use a series of flat Λ cold dark matter cosmological N-body simulations of structure formation, each with a different power spectrum but with the same initial white noise field. Our fiducial simulation is based on parameters from the WMAP seventh year cosmology. We then systematically vary the spectral index, ns ; matter density, Ω M ; and normalization of the power spectrum, σ8, for seven unique simulations. Across these, we study variations in the subhalo mass function, mass fraction, maximum circular velocity function, spatial distribution, concentration, formation times, accretion times, and peak mass. We eliminate dependence of subhalo properties on host halo mass and average the values over many hosts to reduce variance. While the "same" subhalos from identical initial overdensity peaks in higher σ8, ns , and Ω m simulations accrete earlier and end up less massive and closer to the halo center at z = 0, the process of continuous subhalo accretion and destruction leads to a steady state distribution of these properties across all subhalos in a given host. This steady state mechanism eliminates cosmological dependence on all of the properties listed above except for subhalo concentration and V max, which remain greater for higher σ8, ns , and Ω m simulations, and subhalo formation time, which remains earlier. We also find that the numerical technique for computing the scale radius and the halo finder that were used can significantly affect the concentration-mass relationship as computed for a simulation.

  7. A look into the inside of haloes: a characterization of the halo shape as a function of overdensity in the Planck cosmology

    Science.gov (United States)

    Despali, Giulia; Giocoli, Carlo; Bonamigo, Mario; Limousin, Marceau; Tormen, Giuseppe

    2017-04-01

    In this paper, we study the triaxial properties of dark matter haloes of a wide range of masses extracted from a set of cosmological N-body simulations. We measure the shape at different distances from the halo centre (characterized by different overdensity thresholds), both in three and in two dimensions. We discuss how halo triaxiality increases with mass, redshift and distance from the halo centre. We also examine how the orientations of the different ellipsoids are aligned with each other and what is the gradient in internal shapes for haloes with different virial configurations. Our findings highlight that the internal part of the halo retains memory of the violent formation process keeping the major axis oriented towards the preferential direction of the infalling material while the outer part becomes rounder due to continuous isotropic merging events. This effect is clearly evident in high-mass haloes - which formed more recently - while it is more blurred in low-mass haloes. We present simple distributions that may be used as priors for various mass reconstruction algorithms, operating in different wavelengths, in order to recover a more complex and realistic dark matter distribution of isolated and relaxed systems.

  8. Decay Properties of the Halo Nucleus $^{11}$Li

    CERN Multimedia

    2002-01-01

    During the past years a considerable experimental effort has been devoted to the production and study of nuclei close to the neutron and proton drip-lines. The most spectacular phenomenon encountered is the occurrence of neutron halos in the loosely bound neutron rich nuclei. \\\\ \\\\ Another interesting feature, observed at ISOLDE, which most likely is connected to the halo structure, is the very strong (super-allowed) Gamow-Teller $\\beta$- transitions to highly excited states which are systematically observed for the lightest neutron rich drip-line nuclei. These transitions might be viewed as arising from the quasi-free $\\beta$ -decay of the halo neutrons. It is proposed to make a detailed study of the $\\beta$- strength function for $^{11}$Li, a nuclide having a half-life of 8.2 ms and a Q $\\beta$-value of 20.73~MeV. \\\\ \\\\ So far only a lower limit of the Gamow-Teller transition rate to highly excited states ($\\approx$~18.5~MeV) in the daughter nucleus has been obtained from measurements of $\\beta$-delayed tri...

  9. KINEMATICS OF OUTER HALO GLOBULAR CLUSTERS IN M31

    Energy Technology Data Exchange (ETDEWEB)

    Veljanoski, J.; Ferguson, A. M. N.; Bernard, E. J.; Penarrubia, J. [Institute for Astronomy, University of Edinburgh, Royal Observatory, Blackford Hill, Edinburgh EH9 3HJ (United Kingdom); Mackey, A. D. [Research School of Astronomy and Astrophysics, Australian National University, Mt Stromlo Observatory, Weston Creek, ACT 2611 (Australia); Huxor, A. P. [Astronomisches Rechen-Institut, Zentrum fur Astronomie der Universitat Heidelberg, Monchhofstr. 12-14, D-69120 Heidelberg (Germany); Irwin, M. J.; Chapman, S. C. [Institute of Astronomy, University of Cambridge, Madingley Road, Cambridge CB3 0HA (United Kingdom); Cote, P. [NRC Herzberg Institute of Astrophysics, 5071 West Saanich Road, Victoria, British Columbia V9E 2E7 (Canada); Tanvir, N. R.; McConnachie, A. [Department of Physics and Astronomy, University of Leicester, Leicester LE1 7RH (United Kingdom); Ibata, R. A.; Martin, N. F. [Observatoire de Strasbourg, 11 rue de l' Universite, F-67000 Strasbourg (France); Fardal, M. [University of Massachusetts, Department of Astronomy, LGRT 619-E, 710 N. Pleasant Street, Amherst, MA 01003-9305 (United States); Lewis, G. F. [Institute of Astronomy, School of Physics, University of Sydney, NSW 2006 (Australia)

    2013-05-10

    We present the first kinematic analysis of the far outer halo globular cluster (GC) population in the Local Group galaxy M31. Our sample contains 53 objects with projected radii of {approx}20-130 kpc, 44 of which have no previous spectroscopic information. GCs with projected radii {approx}> 30 kpc are found to exhibit net rotation around the minor axis of M31, in the same sense as the inner GCs, albeit with a smaller amplitude of 79 {+-} 19 km s{sup -1}. The rotation-corrected velocity dispersion of the full halo GC sample is 106 {+-} 12 km s{sup -1}, which we observe to decrease with increasing projected radius. We find compelling evidence for kinematic coherence among GCs that project on top of halo substructure, including a clear signature of infall for GCs lying along the northwest stream. Using the tracer mass estimator, we estimate the dynamical mass of M31 within 200 kpc to be M{sub M31} = (1.2-1.5) {+-} 0.2 Multiplication-Sign 10{sup 12} M{sub Sun }. This value is highly dependent on the chosen model and assumptions within.

  10. Hypervelocity Stars: From the Galactic Center to the Halo

    Science.gov (United States)

    Kenyon, Scott J.; Bromley, Benjamin C.; Geller, Margaret J.; Brown, Warren R.

    2008-06-01

    Hypervelocity stars (HVSs) traverse the Galaxy from the central black hole to the outer halo. We show that the Galactic potential within 200 pc acts as a high-pass filter preventing low-velocity HVSs from reaching the halo. To trace the orbits of HVSs throughout the Galaxy, we construct two forms of the potential which reasonably represent the observations in the range 5-105 pc: a simple spherically symmetric model and a bulge-disk-halo model. We use the Hills mechanism (disruption of binaries by the tidal field of the central black hole) to inject HVSs into the Galaxy and to compute the observable spatial and velocity distributions of HVSs with masses in the range 0.6-4 M⊙. These distributions reflect the mass function in the Galactic center, properties of binaries in the Galactic center, and aspects of stellar evolution and the injection mechanism. For 0.6-4 M⊙ main-sequence stars, the fraction of unbound HVSs and the asymmetry of the velocity distribution for their bound counterparts increase with stellar mass. The density profiles for unbound HVSs decline with distance from the Galactic center approximately as r-2 (but are steeper for the most massive stars, which evolve off the main sequence during their travel time from the Galactic center); the density profiles for the bound ejecta decline with distance approximately as r-3. In a survey with a limiting magnitude of Vlesssim 23, the detectability of HVSs (unbound or bound) increases with stellar mass.

  11. Integrated Marketing Communications (IMC di PT Halo Rumah Bernyanyi

    Directory of Open Access Journals (Sweden)

    Rebekka Rismayanti

    2017-01-01

    Full Text Available Abstract: This research aims to describe the effectiveness of Integrated Marketing Communication (IMC in PT Halo Rumah Bernyanyi which, from the perspective of marketing strategy, could be studied by analyzing the segmentation, targeting, and positioning. Using case-study method with in-depth interview, the result shows that the implementation of IMC at PT Halo Rumah Bernyayi is arranged in one single strategy and tend to neglect the complexities of running multi-brand family karaoke-house. This considers as ineffective because it leads to “cannibalization” among brands, especially when costumer’s targetting is overlooked before drafting the IMC plan. Keywords: Business, Integrated Marketing Communication, Marketing   Abstrak: Penelitian ini bertujuan untuk mendeskripsikan efektivitas penerapan Integrated Marketing Communications (IMC yang dilihat dari aspek segmentation, targeting dan positioning. Metode penelitian adalah studi kasus dengan menggunakan wawancara mendalam. Hasil penelitian menunjukkan bahwa penerapan IMC di PT Halo Rumah Bernyanyi dibuat dalam satu strategi dan tidak memerhatikan kompleksitas dari aspek segmentation, targeting dan positioning sebagai pedoman dasar. Langkah tersebut dinilai tidak efektif karena dapat mengakibatkan “kanibalisasi” antar brand, terlebih jika perhatian terhadap target konsumen diabaikan sebelum menyusun perencanaan IMC. Kata Kunci: Bisnis, Integrated Marketing Communications, Pemasaran

  12. Design alternatives for beam halo monitors in high intensity accelerators

    CERN Document Server

    Braun, H; Corsini, R; Lefèvre, T; Schulte, Daniel; Tecker, F A; Welsch, C P

    2005-01-01

    In future high intensity, high energy accelerators it must be ensured that particle losses are minimized as activation of the vacuum chambers or other components makes maintenance and upgrade work time consuming and costly. It is imperative to have a clear understanding of the mechanisms that can lead to halo formation and to have the possibility to test available theoretical models with an adequate experimental setup. Optical transition radiation (OTR) provides an interesting opportunity for linear real-time measurements of the transverse beam profile with a resolution which has been so far at best in the some μm range. However, the dynamic range of standard OTR systems is typically limited and needs to be improved for its application for halo measurements. In this contribution, the existing OTR system as it is installed in the CLIC test facility (CTF3) is analyzed and the contribution of each component to the final image quality discussed. Finally, possible halo measurement techniques based on OTR are pres...

  13. Detecting Hot Gaseous Halos of Galaxies with Arcus

    Science.gov (United States)

    Bregman, Joel N.; Hodges-Kluck, Edmund; Li, Jiangtao; Li, Yunyang; Miller, Matthew; Qu, Zhijie

    2018-01-01

    A long-lived component of galaxies is the hot extended atmosphere with a temperature near the virial temperature. It can contain a significant fraction of the missing baryons and can act as a reservoir of matter for future generations of stars. This extended hot halo is detected around the Milky Way in absorption and emission lines of highly ionized species (e.g., O VII, O VIII), but weighted to be within about 50 kpc. From current data there are not many high fidelity absorption line detections and the lines are badly under-resolved. These shortcomings will be rectified with Arcus, which will provide high-quality line measurements in several ions for about 50 sight lines. Lines will often be resolved, revealing the dynamics of the hot halo, such as rotation and the turbulence resulting from feedback. We show how metallicities will be determined from a comparison of these absorption lines with existing emission line data. Arcus will detect O VII absorption from similar halos around external galaxies, for the first time, and out to ~R200, if not beyond. Using random lines of sight, Arcus will complete the metal census of the Universe.

  14. Dwarf Galaxies in Voids: Dark Matter Halos and Gas Cooling

    Directory of Open Access Journals (Sweden)

    Matthias Hoeft

    2010-01-01

    Full Text Available Galaxy surveys have shown that luminous galaxies are mainly distributed in large filaments and galaxy clusters. The remaining large volumes are virtually devoid of luminous galaxies. This is in concordance with the formation of the large-scale structure in the universe as derived from cosmological simulations. However, the numerical results indicate that cosmological voids are abundantly populated with dark matter haloes which may in principle host dwarf galaxies. Observational efforts have in contrast revealed that voids are apparently devoid of dwarf galaxies. We investigate the formation of dwarf galaxies in voids by hydrodynamical cosmological simulations. Due to the cosmic ultraviolet background radiation low-mass haloes show generally a reduced baryon fraction. We determine the characteristic mass below which dwarf galaxies are baryon deficient. We show that the circular velocity below which the accretion of baryons is suppressed is approximately 40 kms−1. The suppressed baryon accretion is caused by the photo-heating due to the UV background. We set up a spherical halo model and show that the effective equation of the state of the gas in the periphery of dwarf galaxies determines the characteristic mass. This implies that any process which heats the gas around dwarf galaxies increases the characteristic mass and thus reduces the number of observable dwarf galaxies.

  15. Ultra-Deep Imaging: Structure of Disks and Haloes

    Science.gov (United States)

    Knapen, Johan H.; Trujillo, Ignacio

    Deep imaging is a fundamental tool in the study of the outermost structures of galaxies. We review recent developments in ultra-deep imaging of galaxy disks and haloes, highlighting the technical advances as well as the challenges and summarizing observational results in the context of modern theory and simulations. The deepest modern galaxy imaging comes from three main sources: (1) surveys such as the Sloan Digital Sky Survey's Stripe 82 project; (2) very long exposures on small telescopes, including by amateurs; and (3) long exposures on the largest professional telescopes. The technical challenges faced are common in all these approaches and include the treatment of light scattered by atmosphere and telescope/instrument, correct flat fielding and the subtraction of non-galaxy light in the images. We review scientific results on galaxy disks and haloes obtained with deep imaging, including the detection and characterization of stellar haloes, tidal features and stellar streams, disk truncations and thick disks. The area of ultra-deep imaging is still very much unexplored territory, and future work in this area promises significant advances in our understanding of galaxy formation and evolution.

  16. Shot noise and biased tracers: A new look at the halo model

    Science.gov (United States)

    Ginzburg, Dimitry; Desjacques, Vincent; Chan, Kwan Chuen

    2017-10-01

    Shot noise is an important ingredient to any measurement or theoretical modeling of discrete tracers of the large scale structure. Recent work has shown that the shot noise in the halo power spectrum becomes increasingly sub-Poissonian at high mass. Interestingly, while the halo model predicts a shot noise power spectrum in qualitative agreement with the data, it leads to an unphysical white noise in the cross halo-matter and matter power spectrum. In this work, we show that absorbing all the halo model sources of shot noise into the halo fluctuation field leads to meaningful predictions for the shot noise contributions to halo clustering statistics and remove the unphysical white noise from the cross halo-matter statistics. Our prescription straightforwardly maps onto the general bias expansion, so that the renormalized shot noise terms can be expressed as combinations of the halo model shot noises. Furthermore, we demonstrate that non-Poissonian contributions are related to volume integrals over correlation functions and their response to long-wavelength density perturbations. This leads to a new class of consistency relations for discrete tracers, which appear to be satisfied by our reformulation of the halo model. We test our theoretical predictions against measurements of halo shot noise bispectra extracted from a large suite of numerical simulations. Our model reproduces qualitatively the observed sub-Poissonian noise, although it underestimates the magnitude of this effect.

  17. Automatic Inspection During Machining

    Science.gov (United States)

    Ransom, Clyde L.

    1988-01-01

    In experimental manufacturing process, numerically-controlled machine tool temporarily converts into inspection machine by installing electronic touch probes and specially-developed numerical-control software. Software drives probes in paths to and on newly machined parts and collects data on dimensions of parts.

  18. Finite Virtual State Machines

    OpenAIRE

    Senhadji Navarro, Raouf; García Vargas, Ignacio

    2012-01-01

    This letter proposes a new model of state machine called Finite Virtual State Machine (FVSM). A memory-based architecture and a procedure for generating FVSM implementations from Finite State Machines (FSMs) are presented. FVSM implementations provide advantages in speed over conventional RAM-based FSM implementations. The results of experiments prove the feasibility of this approach.

  19. Merger Histories of Galaxy Halos and Implications for Disk Survival

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, Kyle R.; Bullock, James S.; Wechsler, Risa H.; Maller, Ariyeh H.; Zentner, Andrew R.

    2008-05-16

    The authors study the merger histories of galaxy dark matter halos using a high resolution {Lambda}CDM N-body simulation. The merger trees follow {approx} 17,000 halos with masses M{sub 0} = (10{sup 11} - 10{sup 13})h{sup -1}M{sub {circle_dot}} at z = 0 and track accretion events involving objects as small as m {approx_equal} 10{sup 10} h{sup -1}M{sub {circle_dot}}. They find that mass assembly is remarkably self-similar in m/M{sub 0}, and dominated by mergers that are {approx}10% of the final halo mass. While very large mergers, m {approx}> 0.4 M{sub 0}, are quite rare, sizeable accretion events, m {approx} 0.1 M{sub 0}, are common. Over the last {approx} 10 Gyr, an overwhelming majority ({approx} 95%) of Milky Way-sized halos with M{sub 0} = 10{sup 12} h{sup -1}M{sub {circle_dot}} have accreted at least one object with greater total mass than the Milky Way disk (m > 5 x 10{sup 10} h{sup -1}M{sub {circle_dot}}), and approximately 70% have accreted an object with more than twice that mass (m > 10{sup 11} h{sup -1}M{sub {circle_dot}}). The results raise serious concerns about the survival of thin-disk dominated galaxies within the current paradigm for galaxy formation in a {Lambda}CDM universe. in order to achieve a {approx} 70% disk-dominated fraction in Milky Way-sized {Lambda}CDM halos, mergers involving m {approx_equal} 2 x 10{sup 11} h{sup -1}M{sub {circle_dot}} objects must not destroy disks. Considering that most thick disks and bulges contain old stellar populations, the situation is even more restrictive: these mergers must not heat disks or drive gas into their centers to create young bulges.

  20. ML-CIRRUS - the HALO mission on mid latitude cirrus clouds

    Science.gov (United States)

    Voigt, Christiane; Minikin, Andreas; Schumann, Ulrich

    2015-04-01

    Clouds are a major source of uncertainty in current climate predictions. In particular, the observation of cirrus cloud variability and the classification of cirrus cloud properties in distinct meteorological regimes are prone to substantial ambiguities. Here we present results of the ML-CIRRUS mission with the German atmospheric science community high altitude long range aircraft HALO. The first in-situ cloud mission with the new research aircraft combined a state-of-the-art clould instrumentation consisting of 9 wing station probes with a novel aerosol, trace gas and radiation instrumentation and a high spectral resolution LIDAR inside the cabin. Further, a newly designed counter flow virtual impactor system allowed for the detection of ice residuals. In addition, models were specifically developed to support flight planning by forecasts of the occurrence and properties of natural cirrus (CLAMS, ECMWF) and frontal cirrus (WCB-ETH), as well as of aircraft induced clouds (CoCiP). In March and April 2014, the HALO research aircraft performed 16 flights (88 flight hours) in mid-latitude cirrus clouds and contrail cirrus at longitudes from 15 deg W to 15 deg E and latitudes from 36 to 58 deg N. Cirrus clouds with an ice water content stream cirrus, lee wave cirrus and convective clouds - with a strong focus on frontal cirrus. Besides natural cirrus, aircraft induced contrail cirrus were probed during 4 flights and an interesting contrail cirrus outbreak situation was encountered over the Atlantic. Here we present an overview and first results of the ML-CIRRUS mission. Major progress in cloud research will be achieved by combining the analysis of cirrus clouds properties measured with in-situ and remote sensing instrumentation on aircraft with satellite retrievals of clouds and cloud modelling.

  1. Precision machine design

    CERN Document Server

    Slocum, Alexander H

    1992-01-01

    This book is a comprehensive engineering exploration of all the aspects of precision machine design - both component and system design considerations for precision machines. It addresses both theoretical analysis and practical implementation providing many real-world design case studies as well as numerous examples of existing components and their characteristics. Fast becoming a classic, this book includes examples of analysis techniques, along with the philosophy of the solution method. It explores the physics of errors in machines and how such knowledge can be used to build an error budget for a machine, how error budgets can be used to design more accurate machines.

  2. Quantum machine learning

    Science.gov (United States)

    Biamonte, Jacob; Wittek, Peter; Pancotti, Nicola; Rebentrost, Patrick; Wiebe, Nathan; Lloyd, Seth

    2017-09-01

    Fuelled by increasing computer power and algorithmic advances, machine learning techniques have become powerful tools for finding patterns in data. Quantum systems produce atypical patterns that classical systems are thought not to produce efficiently, so it is reasonable to postulate that quantum computers may outperform classical computers on machine learning tasks. The field of quantum machine learning explores how to devise and implement quantum software that could enable machine learning that is faster than that of classical computers. Recent work has produced quantum algorithms that could act as the building blocks of machine learning programs, but the hardware and software challenges are still considerable.

  3. Asynchronized synchronous machines

    CERN Document Server

    Botvinnik, M M

    1964-01-01

    Asynchronized Synchronous Machines focuses on the theoretical research on asynchronized synchronous (AS) machines, which are "hybrids” of synchronous and induction machines that can operate with slip. Topics covered in this book include the initial equations; vector diagram of an AS machine; regulation in cases of deviation from the law of full compensation; parameters of the excitation system; and schematic diagram of an excitation regulator. The possible applications of AS machines and its calculations in certain cases are also discussed. This publication is beneficial for students and indiv

  4. Injection halos of hydrocarbons above oil-gas fields with super-high pressures

    Energy Technology Data Exchange (ETDEWEB)

    Bakhtin, V.V.

    1979-09-01

    We studied the origin of injection halos of hydrocarbons above oil-gas fields with anomalously high formation pressures (AHFP). Using fields in Azerbaydzhan and Chechen-Ingushetiya as an example, we demonstrate the effect of certain factors (in particular, faults and zones of increased macro- and micro-jointing) on the morpholoy of the halos. The intensity of micro-jointing (jointing permeability, three-dimensional density of micro-jointing) is directly connected with vertical dimensions of the halos. We measured halos based on transverse profiles across the Khayan-Kort field and studied the distribution of bitumen saturation within the injection halo. Discovery of injection halos during drilling has enabled us to improve the technology of wiring deep-seated exploratory wells for oil and gas in regions with development of AHFP.

  5. Hydrocarbon halo distribution above oil and gas deposits with abnormally high stratal pressures

    Energy Technology Data Exchange (ETDEWEB)

    Bakhtin, V.V.

    1978-01-01

    An examination is made of the emergence of hydrocarbon halos over oil and gas deposits with abnormally high stratal pressure. Fields in Azerbaidzhan and Checheno-Ingushetiya are used to illustrate the effect of certain factors (particularly fractures, zones with heightened macro and microfissure formation) on halo morphology. A direct relationship was found between the intensity of microfissure formation (fissure permeability, volumetric density of microfissures) and the size of vertically directed halos. Dimensions are given for halos by cross-sectional profiles of the Khayan-Kort field, and information is given on the nature of bitumen saturation distribution within the halo. The identification of halos in the process of drilling will make it possible to improve the technology of cutting deep gas and oil exploratory wells in the regions of abnormally high stratal pressures are developing. 22 references, 4 figures, 1 table.

  6. Group support system and explanatory feedback: An experimental study of mitigating halo effect

    Directory of Open Access Journals (Sweden)

    Intiyas Utami

    2015-12-01

    Full Text Available Comprehensive assessment potentially leads to halo effect that will affect accuracy of auditors decision-making process. Biased initial audit decision will potentially influence final audit decision. It is there-fore necessary to mitigate halo effect that is the consequence of auditors good impression on clients initial condition. This re-search aims to empirically show that halo effect can be mitigated by explanatory feedback and Group Support System (GSS. The researchers experimentally mani-pulate explanatory feedback and GSS using online web-site. The subjects are stu-dents who have already taken auditing courses. The results show that: 1 explanato-ry feedback can mitigate halo effect so that audit decision will be more accurate 2 GSS can also mitigate halo effect 3 explanatory feedback and GSS are the best me-thods to mitigate halo effect.

  7. HaloTag as a reporter gene: positron emission tomography imaging with 64Cu-labeled second generation HaloTag ligands

    Science.gov (United States)

    Hong, Hao; Benink, Hélène A; Uyeda, H Tetsuo; Valdovinos, Hector F; Zhang, Yin; Meisenheimer, Poncho; Barnhart, Todd E; Fan, Frank; Cai, Weibo

    2013-01-01

    The goal of this study is to employ the HaloTag technology for positron emission tomography (PET), which involves two components: the HaloTag protein (a modified hydrolase which covalently binds to synthetic ligands) and HaloTag ligands (HTLs). 4T1 murine breast cancer cells were stably transfected to express HaloTag protein on the surface (termed as 4T1-HaloTag-ECS, ECS denotes extracellular surface). Two new HTLs were synthesized and termed NOTA-HTL2G-S and NOTA-HTL2G-L (2G indicates second generation, S stands for short, L stands for long, NOTA denotes 1,4,7-triazacyclononane-N,N’N’’-triacetic acid). Microscopy studies confirmed surface expression of HaloTag in 4T1-HaloTag-ECS cells, which specifically bind NOTA-HTL2G-S/L. Uptake of 64Cu-NOTA-HTL2G-L in 4T1-HaloTag-ECS tumors (4.3 ± 0.5, 4.1± 0.2, 4.0 ± 0.2, 2.3 ± 0.1, and 2.2 ± 0.1 %ID/g at 0.5, 3, 6, 18, and 24 h post-injection respectively; n = 4) was significantly higher than that in the 4T1 tumors (3.0 ± 0.3, 3.0± 0.1, 3.0 ± 0.2, 2.0 ± 0.4, and 2.4 ± 0.3 %ID/g at 0.5, 3, 6, 18, and 24 h post-injection respectively; n = 4) at early time points. In comparison, 64Cu-NOTA-HTL2G-S did not demonstrate significant uptake in either 4T1-HaloTag-ECS or 4T1 tumors. Blocking studies and autoradiography of tumor lysates confirmed that 64Cu-NOTA-HTL2G-L binds specifically to HaloTag protein in the 4T1-HaloTag-ECS tumors, corroborated by histology. HaloTag protein-specific targeting and PET imaging in vivo with 64Cu-NOTA-HTL2G-L serves as a proof-of-principle for future non-invasive and sensitive tracking of HaloTag-transfected cells with PET, as well as many other studies of gene/protein/cell function in vivo. PMID:23634240

  8. CPM Signal for Machine to Machine Communications

    OpenAIRE

    Messai, Malek

    2015-01-01

    The analysis of communication evolution predicts an increase in the number of connected machines. This thesis aims to determine a multi-user communication system adapted to the material limitation of the machines and to the applications constraints. Power and cost efficient digital modulation is required for both economic and environmental reasons; the power consumption on the link should be as low as possible. Constant envelope modulation offers the possibility to use non-linear cost-effecti...

  9. The Impact of Assembly Bias on the Galaxy Content of Dark Matter Halos

    Science.gov (United States)

    Zehavi, Idit; Contreras, Sergio; Padilla, Nelson; Smith, Nicholas J.; Baugh, Carlton M.; Norberg, Peder

    2018-01-01

    We study the dependence of the galaxy content of dark matter halos on large-scale environment and halo formation time using semi-analytic galaxy models applied to the Millennium simulation. We analyze subsamples of halos at the extremes of these distributions and measure the occupation functions for the galaxies they host. We find distinct differences among these occupation functions. The main effect with environment is that central galaxies (and in one model, also the satellites) in denser regions start populating lower-mass halos. A similar, but significantly stronger, trend exists with halo age, where early-forming halos are more likely to host central galaxies at lower halo mass. We discuss the origin of these trends and the connection to the stellar mass–halo mass relation. We find that, at fixed halo mass, older halos and to some extent also halos in dense environments tend to host more massive galaxies. Additionally, we see a reverse trend for the occupation of satellite galaxies where early-forming halos have fewer satellites, likely due to having more time for them to merge with the central galaxy. We describe these occupancy variations in terms of the changes in the occupation function parameters, which can aid in constructing realistic mock galaxy samples. Finally, we study the corresponding galaxy auto- and cross-correlation functions of the different samples and elucidate the impact of assembly bias on galaxy clustering. Our results can inform theoretical modeling of galaxy assembly bias and attempts to detect it in the real universe.

  10. Pressure at the ISM-halo interface: A reheating frequency dependence

    Directory of Open Access Journals (Sweden)

    Ćirković M.M.

    1998-01-01

    Full Text Available The dependence of the thermal pressure of hot galactic halos on a model parameter describing the frequency of major reheating episodes during galactic history is investigated. Pressure on the interface between interstellar medium and the halo gas is especially interesting, since empirical evidence here offers one of the simplest constraints on halo models. It is shown that two-phase model of Mo & Miralda-Escudé is sufficiently robust with respect to uncertainties in the average interval between reheating.

  11. HaloTag-based purification of functional human kinases from mammalian cells.

    Science.gov (United States)

    Ohana, Rachel Friedman; Hurst, Robin; Vidugiriene, Jolanta; Slater, Michael R; Wood, Keith V; Urh, Marjeta

    2011-04-01

    Although cultured mammalian cells are preferred for producing functional mammalian proteins with appropriate post-translational modifications, purification of recombinant proteins is frequently hampered by low expression. We have addressed this by creating a new method configured specifically for mammalian cell culture that provides rapid detection and efficient purification. This approach is based on HaloTag, a protein fusion tag designed to bind rapidly, selectively and covalently to a series of synthetic ligands that can carry a variety of functional groups, including fluorescent dyes for detection or solid supports for purification. Since the binding of HaloTag to the HaloLink resin is essentially irreversible, it overcomes the equilibrium-based binding limitations associated with affinity tags and enables efficient capture and purification of target protein, even at low expression levels. The target protein is released from the HaloLink resin by specific cleavage using a TEV protease fused to HaloTag (HaloTEV), leaving both HaloTag and HaloTEV permanently attached to the resin and highly pure, tag-free protein in solution. HaloTag fluorescent ligands enable fluorescent labeling of HaloTag fusion proteins, providing a convenient way to monitor expression, and thus facilitate the identification of optimal transient transfection conditions as well as the selection of high expression stable cell lines. The capabilities of this method have been demonstrated by the efficient purification of five functional human kinases from HEK293T cells. In addition, when purifications using FLAG, 3xFLAG, His(6)Tag and HaloTag were performed in parallel, HaloTag was shown to provide significantly higher yields, purity and overall recovery of the expressed proteins. Copyright © 2010 Elsevier Inc. All rights reserved.

  12. HaloTag: a novel reporter gene for positron emission tomography.

    Science.gov (United States)

    Hong, Hao; Benink, Hélène A; Zhang, Yin; Yang, Yunan; Uyeda, H Tetsuo; Engle, Jonathan W; Severin, Gregory W; McDougall, Mark G; Barnhart, Todd E; Klaubert, Dieter H; Nickles, Robert J; Fan, Frank; Cai, Weibo

    2011-08-15

    Among the many molecular imaging techniques, reporter gene imaging has been a dynamic area of research. The HaloTag protein is a modified haloalkane dehalogenase which was designed to covalently bind to synthetic ligands (i.e. the HaloTag ligands [HTL]). Covalent bond formation between the HaloTag protein and the chloroal-kane within the HTL occurs rapidly under physiological conditions, which is highly specific and essentially irreversible. Over the years, HaloTag technology has been investigated for various applications such as in vitro/in vivo imaging, protein purification/trafficking, high-throughput assays, among others. The goal of this study is to explore the use of the HaloTag protein as a novel reporter gene for positron emission tomography (PET) imaging. By attaching a HaloTag -reactive chloroalkane to 1, 4, 7-triazacyclononane-N, N', N"-triacetic acid (NOTA) through hydrophilic linkers, the resulting NOTA-conjugated HTLs were labeled with (64)Cu and tested for PET imaging in living mice bearing 4T1-HaloTag-ECS tumors, which stably express the HaloTag protein on the cell surface. Significantly higher uptake of (64)Cu-NOTA-HTL-S (which contains a short hydrophilic linker) in the 4T1-HaloTag-ECS than the non-HaloTag-expressing 4T1 tumors was observed, which demonstrated the HaloTag specificity of (64)Cu-NOTA-HTL-S and warranted future investigation of the HaloTag protein as a PET reporter gene.

  13. HaloTag Protein-Mediated Specific Labeling of Living Cells with Quantum Dots

    OpenAIRE

    So, Min-kyung; Yao, Hequan; Rao, Jianghong

    2008-01-01

    Quantum dots emerge as an attractive alternative to small molecule fluorophores as fluorescent tags for in vivo cell labeling and imaging. This communication presents a method for specific labeling of live cells using quantum dots. The labeling is mediated by HaloTag protein expressed at the cell surface which forms a stable covalent adduct with its ligand (HaloTag ligand). The labeling can be performed in one single step with quantum dot conjugates that are functionalized with HaloTag ligand...

  14. ZOMG - I. How the cosmic web inhibits halo growth and generates assembly bias

    Science.gov (United States)

    Borzyszkowski, Mikolaj; Porciani, Cristiano; Romano-Díaz, Emilio; Garaldi, Enrico

    2017-07-01

    The clustering of dark matter haloes with fixed mass depends on their formation history, an effect known as assembly bias. We use zoom N-body simulations to investigate the origin of this phenomenon. For each halo at redshift z = 0, we determine the time in which the physical volume containing its final mass becomes stable. We consider five examples for which this happens at z ˜ 1.5 and two that do not stabilize by z = 0. The zoom simulations show that early-collapsing haloes do not grow in mass at z = 0 while late-forming ones show a net inflow. The reason is that 'accreting' haloes are located at the nodes of a network of thin filaments feeding them. Conversely, each 'stalled' halo lies within a prominent filament that is thicker than the halo size. Infalling material from the surroundings becomes part of the filament while matter within it recedes from the halo. We conclude that assembly bias originates from quenching halo growth due to tidal forces following the formation of non-linear structures in the cosmic web, as previously conjectured in the literature. Also the internal dynamics of the haloes change: the velocity anisotropy profile is biased towards radial (tangential) orbits in accreting (stalled) haloes. Our findings reveal the cause of the yet unexplained dependence of halo clustering on the anisotropy. Finally, we extend the excursion-set theory to account for these effects. A simple criterion based on the ellipticity of the linear tidal field combined with the spherical-collapse model provides excellent predictions for both classes of haloes.

  15. Electronics and Calibration system for the CMS Beam Halo Monitor

    CERN Document Server

    Tosi, Nicolo

    2014-01-01

    In the context of increasing luminosity of LHC, it will be important to accurately measure the Machine Induced Background. A new monitoring system will be installed in the CMS cavern for measuring the beam background at high radius. This detector is composed of synthetic quartz Cherenkov radiators, coupled to fast photomultiplier tubes (PMT). The readout chain of this detector will make use of many components developed for the Phase 1 upgrade to the CMS Hadron Calorimeter electronics, with a dedicated firmware and readout adapted to the beam monitoring requirements. The PMT signal will be digitized by a charge integrating ASIC (QIE10), providing both the signal rise time and the charge integrated over one bunch crossing.The backend electronics will record bunch-by-bunch histograms, which will be published to CMS and the LHC using the newly designed CMS beam instrumentation specific DAQ. A calibration monitoring system has been designed to generate triggered pulses of light to monitor the efficiency of the sys...

  16. Perspex machine: VII. The universal perspex machine

    Science.gov (United States)

    Anderson, James A. D. W.

    2006-01-01

    The perspex machine arose from the unification of projective geometry with the Turing machine. It uses a total arithmetic, called transreal arithmetic, that contains real arithmetic and allows division by zero. Transreal arithmetic is redefined here. The new arithmetic has both a positive and a negative infinity which lie at the extremes of the number line, and a number nullity that lies off the number line. We prove that nullity, 0/0, is a number. Hence a number may have one of four signs: negative, zero, positive, or nullity. It is, therefore, impossible to encode the sign of a number in one bit, as floating-point arithmetic attempts to do, resulting in the difficulty of having both positive and negative zeros and NaNs. Transrational arithmetic is consistent with Cantor arithmetic. In an extension to real arithmetic, the product of zero, an infinity, or nullity with its reciprocal is nullity, not unity. This avoids the usual contradictions that follow from allowing division by zero. Transreal arithmetic has a fixed algebraic structure and does not admit options as IEEE, floating-point arithmetic does. Most significantly, nullity has a simple semantics that is related to zero. Zero means "no value" and nullity means "no information." We argue that nullity is as useful to a manufactured computer as zero is to a human computer. The perspex machine is intended to offer one solution to the mind-body problem by showing how the computable aspects of mind and, perhaps, the whole of mind relates to the geometrical aspects of body and, perhaps, the whole of body. We review some of Turing's writings and show that he held the view that his machine has spatial properties. In particular, that it has the property of being a 7D lattice of compact spaces. Thus, we read Turing as believing that his machine relates computation to geometrical bodies. We simplify the perspex machine by substituting an augmented Euclidean geometry for projective geometry. This leads to a general

  17. High-resolution disruption halo current measurements using Langmuir probes in Alcator C-Mod

    Science.gov (United States)

    Tinguely, R. A.; Granetz, R. S.; Berg, A.; Kuang, A. Q.; Brunner, D.; LaBombard, B.

    2018-01-01

    Halo currents generated during disruptions on Alcator C-Mod have been measured with Langmuir ‘rail’ probes. These rail probes are embedded in a lower outboard divertor module in a closely-spaced vertical (poloidal) array. The dense array provides detailed resolution of the spatial dependence (~1 cm spacing) of the halo current distribution in the plasma scrape-off region with high time resolution (400 kHz digitization rate). As the plasma limits on the outboard divertor plate, the contact point is clearly discernible in the halo current data (as an inversion of current) and moves vertically down the divertor plate on many disruptions. These data are consistent with filament reconstructions of the plasma boundary, from which the edge safety factor of the disrupting plasma can be calculated. Additionally, the halo current ‘footprint’ on the divertor plate is obtained and related to the halo flux width. The voltage driving halo current and the effective resistance of the plasma region through which the halo current flows to reach the probes are also investigated. Estimations of the sheath resistance and halo region resistivity and temperature are given. This information could prove useful for modeling halo current dynamics.

  18. Estimating the geoeffectiveness of halo CMEs from associated solar and IP parameters using neural networks

    Directory of Open Access Journals (Sweden)

    J. Uwamahoro

    2012-06-01

    Full Text Available Estimating the geoeffectiveness of solar events is of significant importance for space weather modelling and prediction. This paper describes the development of a neural network-based model for estimating the probability occurrence of geomagnetic storms following halo coronal mass ejection (CME and related interplanetary (IP events. This model incorporates both solar and IP variable inputs that characterize geoeffective halo CMEs. Solar inputs include numeric values of the halo CME angular width (AW, the CME speed (Vcme, and the comprehensive flare index (cfi, which represents the flaring activity associated with halo CMEs. IP parameters used as inputs are the numeric peak values of the solar wind speed (Vsw and the southward Z-component of the interplanetary magnetic field (IMF or Bs. IP inputs were considered within a 5-day time window after a halo CME eruption. The neural network (NN model training and testing data sets were constructed based on 1202 halo CMEs (both full and partial halo and their properties observed between 1997 and 2006. The performance of the developed NN model was tested using a validation data set (not part of the training data set covering the years 2000 and 2005. Under the condition of halo CME occurrence, this model could capture 100% of the subsequent intense geomagnetic storms (Dst ≤ −100 nT. For moderate storms (−100 < Dst ≤ −50, the model is successful up to 75%. This model's estimate of the storm occurrence rate from halo CMEs is estimated at a probability of 86%.

  19. HaloTag: a new versatile reporter gene system in plant cells.

    Science.gov (United States)

    Lang, Christina; Schulze, Jutta; Mendel, Ralf-R; Hänsch, Robert

    2006-01-01

    HaloTag Interchangeable Labeling Technology (HaloTag) was originally developed for mammalian cell analysis. In this report, the use of HaloTag is demonstrated in plant cells for the first time. This system allows different fluorescent colours to be used to visualize the localization of the non-fluorescent HaloTag protein within living cells. A vector was constructed which expresses the HaloTag protein under the control of the 35S promoter of cauliflower mosaic virus. The functionality of the HaloTag construct was tested in transient assays by (i) transforming tobacco protoplasts and (ii) using biolistic transformation of intact leaf cells of tobacco and poplar plants. Two to fourteen days after transformation, the plant material was incubated with ligands specific for labelling the HaloTag protein, and fluorescence was visualized by confocal laser scanning microscopy. The results demonstrate that HaloTag technology is a flexible system which generates efficient fluorescence in different types of plant cells. The ligand-specific labelling of HaloTag protein was not hampered by the plant cell wall.

  20. Discovering Protein Interactions and Characterizing Protein Function Using HaloTag Technology

    National Research Council Canada - National Science Library

    Daniels, Danette L; Méndez, Jacqui; Benink, Hélène; Niles, Andrew; Murphy, Nancy; Ford, Michael; Jones, Richard; Amunugama, Ravi; Allen, David; Urh, Marjeta

    2014-01-01

    .... To specifically address the challenges of understanding the human proteome, we have developed HaloTag technology for protein isolation, particularly strong for isolation of multiprotein complexes...

  1. The upper bound on the lowest mass halo

    Science.gov (United States)

    Jethwa, P.; Erkal, D.; Belokurov, V.

    2018-01-01

    We explore the connection between galaxies and dark matter haloes in the Milky Way (MW) and quantify the implications on properties of the dark matter particle and the phenomenology of low-mass galaxy formation. This is done through a probabilistic comparison of the luminosity function of MW dwarf satellite galaxies to models based on two suites of zoom-in simulations. One suite is dark-matter-only, while the other includes a disc component, therefore we can quantify the effect of the MW's baryonic disc on our results. We apply numerous stellar-mass-halo-mass (SMHM) relations allowing for multiple complexities: scatter, a characteristic break scale, and subhaloes which host no galaxy. In contrast to previous works, we push the model/data comparison to the faintest dwarfs by modelling observational incompleteness, allowing us to draw three new conclusions. First, we constrain the SMHM relation for 102 2.4 × 108 M⊙ (1σ). Secondly, by translating to a warm dark matter (WDM) cosmology, we bound the thermal relic mass mWDM > 2.9 keV at 95 per cent confidence, on a par with recent constraints from the Lyman-α forest. Lastly, we find that the observed number of ultra-faint MW dwarfs is in tension with the theoretical prediction that reionization prevents galaxy formation in almost all 108 M⊙ haloes. This can be tested with the next generation of deep imaging surveys. To this end, we predict the likely number of detectable satellite galaxies in the Subaru/Hyper Suprime-Cam survey and the Large Synoptic Survey Telescope. Confronting these predictions with future observations will be amongst our strongest tests of WDM and the effect reionization on low-mass systems.

  2. HaloTag as a reporter gene: positron emission tomography imaging with (64)Cu-labeled second generation HaloTag ligands.

    Science.gov (United States)

    Hong, Hao; Benink, Hélène A; Uyeda, H Tetsuo; Valdovinos, Hector F; Zhang, Yin; Meisenheimer, Poncho; Barnhart, Todd E; Fan, Frank; Cai, Weibo

    2013-01-01

    THE GOAL OF THIS STUDY IS TO EMPLOY THE HALOTAG TECHNOLOGY FOR POSITRON EMISSION TOMOGRAPHY (PET), WHICH INVOLVES TWO COMPONENTS: the HaloTag protein (a modified hydrolase which covalently binds to synthetic ligands) and HaloTag ligands (HTLs). 4T1 murine breast cancer cells were stably transfected to express HaloTag protein on the surface (termed as 4T1-HaloTag-ECS, ECS denotes extracellular surface). Two new HTLs were synthesized and termed NOTA-HTL2G-S and NOTA-HTL2G-L (2G indicates second generation, S stands for short, L stands for long, NOTA denotes 1,4,7-triazacyclononane-N,N'N''-triacetic acid). Microscopy studies confirmed surface expression of HaloTag in 4T1-HaloTag-ECS cells, which specifically bind NOTA-HTL2G-S/L. Uptake of (64)Cu-NOTA-HTL2G-L in 4T1-HaloTag-ECS tumors (4.3 ± 0.5, 4.1± 0.2, 4.0 ± 0.2, 2.3 ± 0.1, and 2.2 ± 0.1 %ID/g at 0.5, 3, 6, 18, and 24 h post-injection respectively; n = 4) was significantly higher than that in the 4T1 tumors (3.0 ± 0.3, 3.0± 0.1, 3.0 ± 0.2, 2.0 ± 0.4, and 2.4 ± 0.3 %ID/g at 0.5, 3, 6, 18, and 24 h post-injection respectively; n = 4) at early time points. In comparison, (64)Cu-NOTA-HTL2G-S did not demonstrate significant uptake in either 4T1-HaloTag-ECS or 4T1 tumors. Blocking studies and autoradiography of tumor lysates confirmed that (64)Cu-NOTA-HTL2G-L binds specifically to HaloTag protein in the 4T1-HaloTag-ECS tumors, corroborated by histology. HaloTag protein-specific targeting and PET imaging in vivo with (64)Cu-NOTA-HTL2G-L serves as a proof-of-principle for future non-invasive and sensitive tracking of HaloTag-transfected cells with PET, as well as many other studies of gene/protein/cell function in vivo.

  3. Gravitational lensing of wormholes in the galactic halo region

    Energy Technology Data Exchange (ETDEWEB)

    Kuhfittig, Peter K.F. [Milwaukee School of Engineering, Department of Mathematics, Milwaukee, WI (United States)

    2014-03-15

    A recent study by Rahaman et al. has shown that the galactic halo possesses the necessary properties for supporting traversable wormholes, based on two observational results, the Navarro-Frenk-White density profile and the observed flat rotation curves of galaxies. Using a method for calculating the deflection angle pioneered by V. Bozza, it is shown that the deflection angle diverges at the throat of the wormhole. The resulting photon sphere has a radius of about 0.40 ly. Given the dark-matter background, detection may be possible from past data using ordinary light. (orig.)

  4. Charge Radii and Neutron Correlations in Helium Halo Nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Papadimitriou, Georgios [ORNL; Kruppa, A. T. [Institute of Nuclear Research, Debrecen, Hungary; Michel, N. [University of Jyvaskyla; Nazarewicz, W. [University of Tennessee, Knoxville (UTK) & Oak Ridge National Laboratory (ORNL); Ploszajczak, M. [Grand Accelerateur National d' Ions Lourds (GANIL); Rotureau, J. [University of Arizona

    2011-01-01

    Within the complex-energy configuration interaction framework, we study correlations of valence neutrons to explain the behavior of charge radii in the neutron halo nuclei ^{6,8}He. We find that the experimentally observed decrease of the charge radius between ^{6}He and ^{8}He is caused by a subtle interplay between three effects: dineutron correlations, a spin-orbit contribution to the charge radius, and a core swelling effect. We demonstrate that two-neutron angular correlations in the 2^+}_{1} resonance of ^{6}He differ markedly from the ground-state correlations in ^{6,8}He.

  5. MD 2179: Scraping of off-momentum halo after injection

    CERN Document Server

    Garcia Morales, Hector; Patecki, Marcin; Wretborn, Sven Joel; CERN. Geneva. ATS Department

    2018-01-01

    In this MD, a beam scraping was performed using the momentum primary collimator in IR3 where dispersion is high. A second scraping was performed using a TCSG in IR7 where dispersion is almost negligible. In such a way, we aim to disentangle the contribution of off-momentum particles to halo population. These scrapings will provide useful information to better understand the usual off-momentum losses we see at the start of the ramp. The MD results would also be used to benchmark simulations of off-momentum beam losses in order to gain confidence in simulation models.

  6. Flows of Baryons through the Milky Way Halo

    Science.gov (United States)

    Fox, Andrew J.

    2017-07-01

    The Milky Way provides an ideal opportunity to study baryon flows in the circumgalactic medium of a star-forming spiral galaxy. High velocity clouds (HVCs) seen in UV absorption toward background AGN probe the multi-phase ionized gas in the Galactic CGM. In this talk new observations from the Cosmic Origins Spectrograph (COS) on Hubble will be presented, focusing on two Galactic regions: the biconical outflow from the Galactic Center, which drives gas into the Fermi Bubbles, and the Smith Cloud, an accreting HVC close to the Galactic disk showing clear signs of fragmentation. These observations allow us to constrain the rates of gas circulation in the Galactic halo.

  7. Study of galactic halo F(T,TG) wormhole solutions

    Science.gov (United States)

    Sharif, M.; Nazir, Kanwal

    In this paper, we investigate static spherically symmetric wormhole solutions with galactic halo region in the background of F(T,TG) gravity. Here, T represents torsion scalar and TG is teleparallel equivalent Gauss-Bonnet term. For this purpose, we consider a diagonal tetrad and two specific F(T,TG) models. We analyze the wormhole structure through shape function graphically for both models. We also investigate the behavior of null/weak energy conditions. Finally, we evaluate the equilibrium condition to check stability of the wormhole solutions. It is concluded that there exists physically viable wormhole solution only for the first model that turns out to be stable.

  8. Mass measurement of short-lived halo nuclides

    Energy Technology Data Exchange (ETDEWEB)

    Bachelet, C.; Audi, G.; Gaulard, C.; Guenaut, C.; Lunney, D.; De Saint Simon, M.; Thibault, C. [CSNSM-IN2P3-CNRS, Orsay (France); Herfurth, F. [GSI, Darmstadt (Germany)

    2005-09-01

    A direct mass measurement of the very-short-lived halo nuclide {sup 11}Li (T{sub 1/2}=8.7ms) has been performed with the transmission mass spectrometer MISTRAL. The preliminary result for the two-neutron separation energy is S{sub 2n}=376{+-}5 keV, improving the precision seven times with an increase of 20% compared to the previous value. In order to confirm this value, the mass excess of {sup 11}Be has also been measured, ME=20171{+-}4 keV, in good agreement with the previous value. (orig.)

  9. Charge Radius Measurement of the Halo Nucleus $^{11}$Li

    CERN Multimedia

    Kluge, H-J; Kuehl, T; Simon, H; Wang, Haiming; Zimmermann, C; Onishi, T; Tanihata, I; Wakasugi, M

    2002-01-01

    %IS385 %title\\\\ \\\\The root-mean-square charge radius of $^{11}$Li will be determined by measuring the isotope shift of a suitable atomic transition in a laser spectroscopic experiment. Comparing the charge radii of the lithium isotopes obtained by this nuclear-model-independent method with the relevant mass radii obtained before will help to answer the question whether the proton distribution in halo nuclei at the neutron drip-line is decoupled to the first order from their neutron distribution. The necessary experimental sensitivity requires the maximum possible rate of $^{11}$Li nuclei in a beam of low emittance which can only be provided by ISOLDE.

  10. Machining of titanium alloys

    CERN Document Server

    2014-01-01

    This book presents a collection of examples illustrating the resent research advances in the machining of titanium alloys. These materials have excellent strength and fracture toughness as well as low density and good corrosion resistance; however, machinability is still poor due to their low thermal conductivity and high chemical reactivity with cutting tool materials. This book presents solutions to enhance machinability in titanium-based alloys and serves as a useful reference to professionals and researchers in aerospace, automotive and biomedical fields.

  11. Pattern recognition & machine learning

    CERN Document Server

    Anzai, Y

    1992-01-01

    This is the first text to provide a unified and self-contained introduction to visual pattern recognition and machine learning. It is useful as a general introduction to artifical intelligence and knowledge engineering, and no previous knowledge of pattern recognition or machine learning is necessary. Basic for various pattern recognition and machine learning methods. Translated from Japanese, the book also features chapter exercises, keywords, and summaries.

  12. Machinability of advanced materials

    CERN Document Server

    Davim, J Paulo

    2014-01-01

    Machinability of Advanced Materials addresses the level of difficulty involved in machining a material, or multiple materials, with the appropriate tooling and cutting parameters.  A variety of factors determine a material's machinability, including tool life rate, cutting forces and power consumption, surface integrity, limiting rate of metal removal, and chip shape. These topics, among others, and multiple examples comprise this research resource for engineering students, academics, and practitioners.

  13. Machine listening intelligence

    Science.gov (United States)

    Cella, C. E.

    2017-05-01

    This manifesto paper will introduce machine listening intelligence, an integrated research framework for acoustic and musical signals modelling, based on signal processing, deep learning and computational musicology.

  14. Nanocomposites for Machining Tools

    Directory of Open Access Journals (Sweden)

    Daria Sidorenko

    2017-10-01

    Full Text Available Machining tools are used in many areas of production. To a considerable extent, the performance characteristics of the tools determine the quality and cost of obtained products. The main materials used for producing machining tools are steel, cemented carbides, ceramics and superhard materials. A promising way to improve the performance characteristics of these materials is to design new nanocomposites based on them. The application of micromechanical modeling during the elaboration of composite materials for machining tools can reduce the financial and time costs for development of new tools, with enhanced performance. This article reviews the main groups of nanocomposites for machining tools and their performance.

  15. Rotating electrical machines

    CERN Document Server

    Le Doeuff, René

    2013-01-01

    In this book a general matrix-based approach to modeling electrical machines is promulgated. The model uses instantaneous quantities for key variables and enables the user to easily take into account associations between rotating machines and static converters (such as in variable speed drives).   General equations of electromechanical energy conversion are established early in the treatment of the topic and then applied to synchronous, induction and DC machines. The primary characteristics of these machines are established for steady state behavior as well as for variable speed scenarios. I

  16. Induction machine handbook

    CERN Document Server

    Boldea, Ion

    2002-01-01

    Often called the workhorse of industry, the advent of power electronics and advances in digital control are transforming the induction motor into the racehorse of industrial motion control. Now, the classic texts on induction machines are nearly three decades old, while more recent books on electric motors lack the necessary depth and detail on induction machines.The Induction Machine Handbook fills industry's long-standing need for a comprehensive treatise embracing the many intricate facets of induction machine analysis and design. Moving gradually from simple to complex and from standard to

  17. Machine learning with R

    CERN Document Server

    Lantz, Brett

    2013-01-01

    Written as a tutorial to explore and understand the power of R for machine learning. This practical guide that covers all of the need to know topics in a very systematic way. For each machine learning approach, each step in the process is detailed, from preparing the data for analysis to evaluating the results. These steps will build the knowledge you need to apply them to your own data science tasks.Intended for those who want to learn how to use R's machine learning capabilities and gain insight from your data. Perhaps you already know a bit about machine learning, but have never used R; or

  18. Nanocomposites for Machining Tools

    DEFF Research Database (Denmark)

    Sidorenko, Daria; Loginov, Pavel; Mishnaevsky, Leon

    2017-01-01

    . A promising way to improve the performance characteristics of these materials is to design new nanocomposites based on them. The application of micromechanical modeling during the elaboration of composite materials for machining tools can reduce the financial and time costs for development of new tools......Machining tools are used in many areas of production. To a considerable extent, the performance characteristics of the tools determine the quality and cost of obtained products. The main materials used for producing machining tools are steel, cemented carbides, ceramics and superhard materials......, with enhanced performance. This article reviews the main groups of nanocomposites for machining tools and their performance....

  19. Nanocomposites for Machining Tools.

    Science.gov (United States)

    Sidorenko, Daria; Loginov, Pavel; Mishnaevsky, Leon; Levashov, Evgeny

    2017-10-13

    Machining tools are used in many areas of production. To a considerable extent, the performance characteristics of the tools determine the quality and cost of obtained products. The main materials used for producing machining tools are steel, cemented carbides, ceramics and superhard materials. A promising way to improve the performance characteristics of these materials is to design new nanocomposites based on them. The application of micromechanical modeling during the elaboration of composite materials for machining tools can reduce the financial and time costs for development of new tools, with enhanced performance. This article reviews the main groups of nanocomposites for machining tools and their performance.

  20. Electrical machines & drives

    CERN Document Server

    Hammond, P

    1985-01-01

    Containing approximately 200 problems (100 worked), the text covers a wide range of topics concerning electrical machines, placing particular emphasis upon electrical-machine drive applications. The theory is concisely reviewed and focuses on features common to all machine types. The problems are arranged in order of increasing levels of complexity and discussions of the solutions are included where appropriate to illustrate the engineering implications. This second edition includes an important new chapter on mathematical and computer simulation of machine systems and revised discussions o

  1. Tribology in machine design

    CERN Document Server

    Stolarski, Tadeusz

    1999-01-01

    ""Tribology in Machine Design is strongly recommended for machine designers, and engineers and scientists interested in tribology. It should be in the engineering library of companies producing mechanical equipment.""Applied Mechanics ReviewTribology in Machine Design explains the role of tribology in the design of machine elements. It shows how algorithms developed from the basic principles of tribology can be used in a range of practical applications within mechanical devices and systems.The computer offers today's designer the possibility of greater stringen

  2. Nanocomposites for Machining Tools

    Science.gov (United States)

    Loginov, Pavel; Mishnaevsky, Leon; Levashov, Evgeny

    2017-01-01

    Machining tools are used in many areas of production. To a considerable extent, the performance characteristics of the tools determine the quality and cost of obtained products. The main materials used for producing machining tools are steel, cemented carbides, ceramics and superhard materials. A promising way to improve the performance characteristics of these materials is to design new nanocomposites based on them. The application of micromechanical modeling during the elaboration of composite materials for machining tools can reduce the financial and time costs for development of new tools, with enhanced performance. This article reviews the main groups of nanocomposites for machining tools and their performance. PMID:29027926

  3. Diamond machine tool face lapping machine

    Science.gov (United States)

    Yetter, H.H.

    1985-05-06

    An apparatus for shaping, sharpening and polishing diamond-tipped single-point machine tools. The isolation of a rotating grinding wheel from its driving apparatus using an air bearing and causing the tool to be shaped, polished or sharpened to be moved across the surface of the grinding wheel so that it does not remain at one radius for more than a single rotation of the grinding wheel has been found to readily result in machine tools of a quality which can only be obtained by the most tedious and costly processing procedures, and previously unattainable by simple lapping techniques.

  4. A search for massive compact halo objects in our galaxy

    Energy Technology Data Exchange (ETDEWEB)

    Alock, C.; Axelrod, T.; Cook, K.; Park, H. (Lawrence Livermore National Lab., CA (USA)); Griest, K.; Stubbs, C. (California Univ., Berkeley, CA (USA). Center for Particle Astrophysics); Freeman, K.; Peterson, B.; Quinn, P.; Rodgers, A. (Australian National Univ., Canberra (Australia). Mount Stromlo and Siding Spring Observatories); Bennett, D.P.

    1990-12-19

    MAssive Compact Halo Objects such as brown dwarfs, Jupiters, and black holes are prime candidates to comprise the dark halo of our galaxy. Paczynski noted that these objects (dubbed MACHOs) can be detected via gravitational microlensing of stars in the Magellanic Clouds with the caveat that only about one in 10{sup 6} stars will be lensed at any given time. Our group is currently involved in constructing a dedicated observing system at the Mount Stromlo Observatory in Australia. We will use a refurbished 1.27 meter telescope and an innovative two-color CCD camera with 3.4 {times} 10{sup 7} pixels to monitor 10{sup 6} {minus} 10{sup 7} stars in the Magellanic Clouds. During the first year of operation (1991--1992), we hope to detect (or rule out) objects in the mass range 0.001M{sub {circle dot}} {le} M {le} 0.1M{sub {circle dot}}, and after five years, we hope to have covered the range 10{sup {minus}6}M{sub {circle dot}} < M {approx lt} 100M{sub {circle dot}}. 4 refs.

  5. Halo Skeletal Fixation: Techniques of Application and Prevention of Complications.

    Science.gov (United States)

    Botte; Byrne; Abrams; Garfin

    1996-01-01

    The halo skeletal fixator provides the most rigid cervical immobilization of all orthoses. However, complications such as pin loosening and infection are common. Appreciation of local anatomy and adherence to established application guidelines should minimize pin-related problems. A relatively safe zone for anterior pin placement is located 1 cm above the orbital rim and superior to the lateral two thirds of the orbit. Posterior pin-site locations are less critical; positioning on the posterolateral aspect of the skull, diagonal to the contralateral anterior pins, is generally desirable. Pins should enter the skull perpendicular to the cortex, with the ring or crown sitting below the widest portion of the skull and passing about 1 cm above the helix of the ear. Pins are inserted at a torque of 8 in-lb and retightened once to 8 in-lb at 48 hours. A loose pin can be retightened to 8 in-lb if resistance is met; otherwise, a loose pin should be replaced at a nearby site. Superficially infected pins are managed with local pin care and oral antibiotics. Persistent or severe infections require pin replacement to a nearby site, parenteral antibiotic therapy, and incision and drainage as needed. In-ability to maintain acceptable cervical reduction with a halo fixator is an indication for alternative treatment, such as internal fixation or traction.

  6. Stellar haloes in massive early-type galaxies

    Science.gov (United States)

    Buitrago, F.

    2017-03-01

    The Hubble Ultra Deep Field (HUDF) opens up an unique window to witness galaxy assembly at all cosmic distances. Thanks to its extraordinary depth, it is a privileged tool to beat the cosmological dimming, which affects any extragalactic observations and has a very strong dependence with redshift (1 +z)^4. In particular, massive (M_{stellar}>5 × 10^{10} M_⊙) Early Type Galaxies (ETGs) are the most interesting candidates for these studies, as they must grow in an inside-out fashion developing an extended stellar envelope/halo that accounts for their remarkable size evolution (˜5 times larger in the nearby Universe than at z=2-3). To this end we have analysed the 6 most massive ETGs at z data reduction and the exhaustive treatment of the Point Spread Function (PSF), we are able to trace the galaxy surface brightness profiles up to the same levels as in the local Universe but this time at = 0.65 (31 mag arcsec^{-2} in all 8 HST bands, ˜ 29 mag arcsec^{-2} restframe or beyond 25 effective radii). This fact enables us to investigate the galactic outskirts or stellar haloes at a previously unexplored era, characterising their light and mass profiles, colors and for the first time the amount of mass in ongoing mergers.

  7. Evidence against cuspy dark matter haloes in large galaxies

    Science.gov (United States)

    Rodrigues, Davi C.; del Popolo, Antonino; Marra, Valerio; de Oliveira, Paulo L. C.

    2017-09-01

    We develop and apply new techniques to uncover systematic effects in galaxy rotation curves (RCs). Considering that an ideal dark matter (DM) profile should yield RCs that have no bias towards any particular radius, we find that the Burkert DM profile satisfies the test, while the Navarro-Frenk-While (NFW) profile is better at fitting the region between one and two disc scale lengths than the inner disc scale length region. Our sample indicates that this behaviour happens to more than 75 per cent of the galaxies fitted with an NFW halo. Also, this tendency is not weakened by considering large galaxies, for instance those with M* ≳ 1010 M⊙. Besides the tests on the homogeneity of the fits, we also use a sample of 62 galaxies of diverse types to test the quality of the overall fit of each galaxy, and to search for correlations with stellar mass, gas mass and the disc scale length. In particular, we find that only 13 galaxies are better fitted by the NFW halo, and that even for the galaxies with M* ≳ 1010 M⊙, the Burkert profile either fits as well as, or better than, the NFW profile. This result is relevant since different baryonic effects important for the smaller galaxies, like supernova feedback and dynamical friction from baryonic clumps, indicate that at such large stellar masses the NFW profile should be preferred over the Burkert profile. Hence, our results suggest either there is a new baryonic effect or a change to the DM physics is required.

  8. The phase-space structure of tidally stripped haloes

    Science.gov (United States)

    Drakos, Nicole E.; Taylor, James E.; Benson, Andrew J.

    2017-06-01

    We propose a new method for generating equilibrium models of spherical systems of collisionless particles that are finite in extent, but whose central regions resemble dark matter haloes from cosmological simulations. This method involves iteratively removing unbound particles from a Navarro-Frenk-White (NFW) profile truncated sharply at some radius. The resulting models are extremely stable, and thus provide a good starting point for N-body simulations of isolated haloes. We provide a code to generate such models for NFW and a variety of other common density profiles. We then develop an analytic approximation to this truncated distribution function. Our method proceeds by analogy with the King model, truncating and shifting the original distribution function of an infinitely extended NFW profile in energy space. We show that the density profiles of our models closely resemble the tidally truncated density profiles seen previously in studies of satellite evolution. Pursuing this analogy further with a series of simulations of tidal mass-loss, we find that our models provide a good approximation to the full distribution function of tidally stripped systems, thus allowing theoretically motivated phase-space calculations for such systems.

  9. Interaction of cosmic rays with cold clouds in galactic haloes

    Science.gov (United States)

    Wiener, Joshua; Oh, S. Peng; Zweibel, Ellen G.

    2017-05-01

    We investigate the effects of cosmic ray (CR) dynamics on cold, dense clouds embedded in a hot, tenuous galactic halo. If the magnetic field does not increase too much inside the cloud, the local reduction in Alfvén speed imposes a bottleneck on CRs streaming out from the star-forming galactic disc. The bottleneck flattens the upstream CR gradient in the hot gas, implying that multiphase structure could have global effects on CR-driven winds. A large CR pressure gradient can also develop on the outward-facing edge of the cloud. This pressure gradient has two independent effects. The CRs push the cloud upwards, imparting it with momentum. On smaller scales, the CRs pressurize cold gas in the fronts, reducing its density, consistent with the low densities of cold gas inferred in recent Cosmic Origins Spectrograph (COS) observations of local L* galaxies. They also heat the material at the cloud edge, broadening the cloud-halo interface and causing an observable change in interface ionic abundances. Due to the much weaker temperature dependence of CR heating relative to thermal-conductive heating, CR mediated fronts have a higher ratio of low-to-high ions compared to conduction fronts, in better agreement with observations. We investigate these effects separately using 1D simulations and analytic techniques.

  10. DAMA RESULTS: DARK MATTER IN THE GALACTIC HALO

    Directory of Open Access Journals (Sweden)

    R. Bernabei

    2013-12-01

    Full Text Available Experimental efforts and theoretical developmens support that most of the Universe is Dark and a large fraction of it should be made of relic particles; many possibilities are open on their nature and interaction types. In particular, the DAMA/LIBRA experiment at Gran Sasso Laboratory (sensitive mass: ~250 kg is mainly devoted to the investigation of Dark Matter (DM particles in the Galactic halo by exploiting the model independent DM annual modulation signature with higly radiopure Na I(Tl targets. DAMA/LIBRA is the succesor of the first generation DAMA/NaI (sensitive mass: ~100 kg; cumulatively the two experiments have released so far the results obtained by analyzing an exposure of 1.17 t yr, collected over 13 annual cycles. The data show a model independent evidence of the presence of DM particles in the galactic halo at 8.9σ confidence level (C.L.. Some of the already achieved results are shortly reminded, the last upgrade occurred at fall 2010 is mentioned and future perspectives are sumarized.

  11. The bias of weighted dark matter halos from peak theory

    CERN Document Server

    Verde, Licia; Simpson, Fergus; Alvarez-Gaume, Luis; Heavens, Alan; Matarrese, Sabino

    2014-01-01

    We give an analytical form for the weighted correlation function of peaks in a Gaussian random field. In a cosmological context, this approach strictly describes the formation bias and is the main result here. Nevertheless, we show its validity and applicability to the evolved cosmological density field and halo field, using Gaussian random field realisations and dark matter N-body numerical simulations. Using this result from peak theory we compute the bias of peaks (and dark matter halos) and show that it reproduces results from the simulations at the ${\\mathcal O}(10\\%)$ level. Our analytical formula for the bias predicts a scale-dependent bias with two characteristics: a broad band shape which, however, is most affected by the choice of weighting scheme and evolution bias, and a more robust, narrow feature localised at the BAO scale, an effect that is confirmed in simulations. This scale-dependent bias smooths the BAO feature but, conveniently, does not move it. We provide a simple analytic formula to des...

  12. Keck Spectroscopy of NGVS Sources: Milky Way Halo Star Kinematics

    Science.gov (United States)

    Zhang, Hao; Guhathakurta, Puragra; Peng, Eric W.; Toloba, Elisa; Next Generation Virgo Cluster Survey (NGVS) Collaboration

    2017-01-01

    We present a study of the kinematics of main sequence turnoff stars in the halo of the Milky Way based on Next Generation Virgo Cluster Survey photometry and Keck/DEIMOS spectroscopic follow-up. Specifically, we investigate the properties of the Virgo overdensity and Sagittarius stream Milky Way halo substructures in the foreground of the Virgo Cluster of galaxies. We use an inverse concentration (iC) parameter that characterizes the angular size of a source, which is defined by the magnitude difference measured by two different apertures for the same object. After combining this information as well as redshift measured from spectra into a Z vs iC plot, all of the objects are separated clearly into three categories: foreground Milky Way stars, Virgo globular clusters, and background galaxies. Most objects located in unexpected regions in the V_iC plot are subsequently rejected through a rigorous examination due to low spectral quality or bad imaging quality, indicating that our sample selection approach gives a very clean classification. We then select Sagittarius stream stars and Virgo overdensity stars out of the foreground star sample to characterize their distributions of spatial position, radial velocity and metallicity, from which we can probe deeper into the history of structure formation in the Milky Way Galaxy. This research was supported by NASA and the National Science Foundation. HZ has been sponsored by China Scholarship Council to carry out this research project at University of California, Santa Cruz.

  13. La abundancia de galaxias y halos de materia oscura en el universo CDM

    Science.gov (United States)

    Abadi, M. G.; Benítez-Llambay, A.; Ferrero, I.

    A long-standing puzzle of CDM cosmological model concerns to the different shape of the galaxy stellar mass function and the halo mass function on dwarf galaxy scales. Dwarf galaxies are much less numerous than halos massive enough to host them; suggesting a complex non-linear relation between the mass of a galaxy and the mass of its surrounding halo. Usually; this is reconciled by appealing to baryonic processes that can reduce the efficiency of galaxy formation in low-mass halos. Recent work applying the abundance matching technique require that virtually no dwarf galaxies form in halos with virial mass below . We use rotation curves of dwarf galaxies compiled from the literature to explore whether their total enclosed mass is consistent with these constraints. Almost one-half of the dwarfs in our sample are at odds with this restriction; they are in halos with masses substantially below . Using a cosmological simulation of the formation of the Local Group of galaxies we found that ram-pressure stripping against the cosmic web removes baryons from low-mass halos without appealing to feedback or reionization. This mechanism may help to explain the scarcity of dwarf galaxies compared with the numerous low-mass halos expected in CDM and the large diversity of star formation histories and morphologies characteristic of faint galaxies. FULL TEXT IN SPANISH

  14. 77 FR 47114 - Manufacturer of Controlled Substances; Notice of Application; Halo Pharmaceutical Inc.

    Science.gov (United States)

    2012-08-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Halo Pharmaceutical... that on July 6, 2012, Halo Pharmaceutical Inc., 30 North Jefferson Road, Whippany, New Jersey 07981...

  15. 78 FR 51210 - Manufacturer of Controlled Substances; Notice of Application; Halo Pharmaceutical, Inc.

    Science.gov (United States)

    2013-08-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Halo Pharmaceutical... that on July 8, 2013, Halo Pharmaceutical, Inc., 30 North Jefferson Road, Whippany, New Jersey 07981...

  16. Alignments of Dark Matter Halos with Large-scale Tidal Fields: Mass and Redshift Dependence

    Science.gov (United States)

    Chen, Sijie; Wang, Huiyuan; Mo, H. J.; Shi, Jingjing

    2016-07-01

    Large-scale tidal fields estimated directly from the distribution of dark matter halos are used to investigate how halo shapes and spin vectors are aligned with the cosmic web. The major, intermediate, and minor axes of halos are aligned with the corresponding tidal axes, and halo spin axes tend to be parallel with the intermediate axes and perpendicular to the major axes of the tidal field. The strengths of these alignments generally increase with halo mass and redshift, but the dependence is only on the peak height, ν \\equiv {δ }{{c}}/σ ({M}{{h}},z). The scaling relations of the alignment strengths with the value of ν indicate that the alignment strengths remain roughly constant when the structures within which the halos reside are still in a quasi-linear regime, but decreases as nonlinear evolution becomes more important. We also calculate the alignments in projection so that our results can be compared directly with observations. Finally, we investigate the alignments of tidal tensors on large scales, and use the results to understand alignments of halo pairs separated at various distances. Our results suggest that the coherent structure of the tidal field is the underlying reason for the alignments of halos and galaxies seen in numerical simulations and in observations.

  17. The f(Script R) halo mass function in the cosmic web

    Science.gov (United States)

    von Braun-Bates, F.; Winther, H. A.; Alonso, D.; Devriendt, J.

    2017-03-01

    An important indicator of modified gravity is the effect of the local environment on halo properties. This paper examines the influence of the local tidal structure on the halo mass function, the halo orientation, spin and the concentration-mass relation. We use the excursion set formalism to produce a halo mass function conditional on large-scale structure. Our simple model agrees well with simulations on large scales at which the density field is linear or weakly non-linear. Beyond this, our principal result is that f(Script R) does affect halo abundances, the halo spin parameter and the concentration-mass relationship in an environment-independent way, whereas we find no appreciable deviation from \\text{ΛCDM} for the mass function with fixed environment density, nor the alignment of the orientation and spin vectors of the halo to the eigenvectors of the local cosmic web. There is a general trend for greater deviation from \\text{ΛCDM} in underdense environments and for high-mass haloes, as expected from chameleon screening.

  18. Abort Options for Human Missions to Earth-Moon Halo Orbits

    Science.gov (United States)

    Jesick, Mark C.

    2013-01-01

    Abort trajectories are optimized for human halo orbit missions about the translunar libration point (L2), with an emphasis on the use of free return trajectories. Optimal transfers from outbound free returns to L2 halo orbits are numerically optimized in the four-body ephemeris model. Circumlunar free returns are used for direct transfers, and cislunar free returns are used in combination with lunar gravity assists to reduce propulsive requirements. Trends in orbit insertion cost and flight time are documented across the southern L2 halo family as a function of halo orbit position and free return flight time. It is determined that the maximum amplitude southern halo incurs the lowest orbit insertion cost for direct transfers but the maximum cost for lunar gravity assist transfers. The minimum amplitude halo is the most expensive destination for direct transfers but the least expensive for lunar gravity assist transfers. The on-orbit abort costs for three halos are computed as a function of abort time and return time. Finally, an architecture analysis is performed to determine launch and on-orbit vehicle requirements for halo orbit missions.

  19. On the shape of dark matter haloes from MultiDark Planck simulations

    Science.gov (United States)

    Vega-Ferrero, Jesús; Yepes, Gustavo; Gottlöber, Stefan

    2017-05-01

    The halo shape plays a central role in determining important observational properties of the haloes such as mass, concentration and lensing cross-sections. The triaxiality of lensing galaxy clusters has a substantial impact on the distribution of the largest Einstein radii, while weak lensing techniques are sensitive to the intrinsic halo ellipticity. In this work, we provide scaling relations for the shapes of dark matter haloes as a function of mass (peak height) and redshift over more than four orders of magnitude in halo masses, namely from 1011.5 to 1015.8 h-1 M⊙. We have analysed four dark matter only simulations from the MultiDark cosmological simulation suite with more than 56 billion particles within boxes of 4.0, 2.5, 1.0 and 0.4 h-1 Gpc size assuming Planck cosmology. The dark matter haloes have been identified in the simulations using the rockstar halo finder, which also determines the axis ratios in terms of the diagonalization of the inertia tensor. In order to infer the shape for a hypothetical halo of a given mass at a given redshift, we provide fitting functions to the minor-to-major and intermediate-to-major axis ratios as a function of the peak height.

  20. Halo statistics analysis within medium volume cosmological N-body simulation

    Directory of Open Access Journals (Sweden)

    Martinović N.

    2015-01-01

    Full Text Available In this paper we present halo statistics analysis of a ΛCDM N body cosmological simulation (from first halo formation until z = 0. We study mean major merger rate as a function of time, where for time we consider both per redshift and per Gyr dependence. For latter we find that it scales as the well known power law (1 + zn for which we obtain n = 2.4. The halo mass function and halo growth function are derived and compared both with analytical and empirical fits. We analyse halo growth through out entire simulation, making it possible to continuously monitor evolution of halo number density within given mass ranges. The halo formation redshift is studied exploring possibility for a new simple preliminary analysis during the simulation run. Visualization of the simulation is portrayed as well. At redshifts z = 0−7 halos from simulation have good statistics for further analysis especially in mass range of 1011 − 1014 M./h. [176021 ’Visible and invisible matter in nearby galaxies: theory and observations

  1. The build up of the correlation between halo spin and the large-scale structure

    Science.gov (United States)

    Wang, Peng; Kang, Xi

    2018-01-01

    Both simulations and observations have confirmed that the spin of haloes/galaxies is correlated with the large-scale structure (LSS) with a mass dependence such that the spin of low-mass haloes/galaxies tend to be parallel with the LSS, while that of massive haloes/galaxies tend to be perpendicular with the LSS. It is still unclear how this mass dependence is built up over time. We use N-body simulations to trace the evolution of the halo spin-LSS correlation and find that at early times the spin of all halo progenitors is parallel with the LSS. As time goes on, mass collapsing around massive halo is more isotropic, especially the recent mass accretion along the slowest collapsing direction is significant and it brings the halo spin to be perpendicular with the LSS. Adopting the fractional anisotropy (FA) parameter to describe the degree of anisotropy of the large-scale environment, we find that the spin-LSS correlation is a strong function of the environment such that a higher FA (more anisotropic environment) leads to an aligned signal, and a lower anisotropy leads to a misaligned signal. In general, our results show that the spin-LSS correlation is a combined consequence of mass flow and halo growth within the cosmic web. Our predicted environmental dependence between spin and large-scale structure can be further tested using galaxy surveys.

  2. Synthesis of organothioacrylonitriles and organoselenoacrylonitriles by reaction of 1-Halo-1-chalcogenoalkenes with CuCN

    Energy Technology Data Exchange (ETDEWEB)

    Silveira, Claudio C.; Caliari, Vinicius; Vieira, Adriano S.; Mendes, Samuel R. [Universidade Federal de Santa Maria (UFSM), RS (Brazil). Dept. de Quimica]. E-mail: silveira@quimica.ufsm.br

    2007-07-01

    Reaction of 1-halo-1-organothio or 1-halo-1-organoseleno alkenes with CuCN in NMP as solvent provides {alpha}-phenylthio or {alpha}-phenylseleno acrylonitriles in good yields. The reaction showed a low stereoselectivity and the products were obtained as E/Z mixtures of isomers. (author)

  3. Structure and substructure in the stellar halo of the Milky Way

    NARCIS (Netherlands)

    Pila Díez, Berenice

    2015-01-01

    In this thesis we present research on the stellar halo of our Galaxy. In particular we focus on measuring the shape and profile of the stellar halo through photometric techniques and main sequence turnoff point star counts. We also present a cross-correlation algorithm that can detect stellar

  4. 40 CFR 721.10063 - Halo substituted hydroxy nitrophenyl amide (generic).

    Science.gov (United States)

    2010-07-01

    ... amide (generic). 721.10063 Section 721.10063 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Specific Chemical Substances § 721.10063 Halo substituted hydroxy nitrophenyl amide (generic). (a) Chemical... as halo substituted hydroxy nitrophenyl amide (PMN P-04-792) is subject to reporting under this...

  5. The mass function of unprocessed dark matter haloes and merger tree branching rates

    Science.gov (United States)

    Benson, Andrew J.

    2017-05-01

    A common approach in semi-analytic modelling of galaxy formation is to construct Monte Carlo realizations of merger histories of dark matter haloes whose masses are sampled from a halo mass function. Both the mass function itself and the merger rates used to construct merging histories are calibrated to N-body simulations. Typically, 'backsplash' haloes (those which were once subhaloes within a larger halo, but which have since moved outside of the halo) are counted in both the halo mass functions and in the merger rates (or, equivalently, progenitor mass functions). This leads to a double counting of mass in Monte Carlo merger histories, which will bias results relative to N-body results. We measure halo mass functions and merger rates with this double counting removed in a large, cosmological N-body simulation with cosmological parameters consistent with current constraints. Furthermore, we account for the inherently noisy nature of N-body halo mass estimates when fitting functions to N-body data, and show that ignoring these errors leads to a significant systematic bias given the precision statistics available from state-of-the-art N-body cosmological simulations.

  6. The shape of dark matter haloes in the Aquarius simulations : evolution and memory

    NARCIS (Netherlands)

    Vera-Ciro, Carlos A.; Sales, Laura V.; Helmi, Amina; Frenk, Carlos S.; Navarro, Julio F.; Springel, Volker; Vogelsberger, Mark; White, Simon D. M.

    We use the high-resolution cosmological N-body simulations from the Aquarius project to investigate in detail the mechanisms that determine the shape of Milky Way type dark matter haloes. We find that, when measured at the instantaneous virial radius, the shape of individual haloes changes with

  7. The kinematics of globular clusters systems in the outer halos of the Aquarius simulations

    NARCIS (Netherlands)

    Veljanoski, J.; Helmi, A.

    2016-01-01

    Stellar halos and globular cluster (GC) systems contain valuable information regarding the assembly history of their host galaxies. Motivated by the detection of a significant rotation signal in the outer halo GC system of M 31, we investigate the likelihood of detecting such a rotation signal in

  8. The shape of dark matter haloes in the Aquarius simulations : Evolution and memory

    NARCIS (Netherlands)

    Vera-Ciro, C.A.; Sales, L. V.; Helmi, A.; Reyle, C; Robin, A; Schultheis, M

    We use the high resolution cosmological N-body simulations from the Aquarius project to investigate in detail the mechanisms that determine the shape of Milky Way-type dark matter haloes. We find that, when measured at the instantaneous virial radius, the shape of individual haloes changes with

  9. The shape of dark matter haloes in the Aquarius simulations: Evolution and memory

    NARCIS (Netherlands)

    Vera-Ciro, C. A.; Sales, L. V.; Helmi, A.

    We use the high resolution cosmological N-body simulations from the Aquarius project to investigate in detail the mechanisms that determine the shape of Milky Way-type dark matter haloes. We find that, when measured at the instantaneous virial radius, the shape of individual haloes changes with

  10. The shape of dark matter haloes in the Aquarius simulations: Evolution and memory

    Directory of Open Access Journals (Sweden)

    Sales L.V.

    2012-02-01

    Full Text Available We use the high resolution cosmological N-body simulations from the Aquarius project to investigate in detail the mechanisms that determine the shape of Milky Way-type dark matter haloes. We find that, when measured at the instantaneous virial radius, the shape of individual haloes changes with time, evolving from a typically prolate configuration at early stages to a more triaxial/oblate geometry at the present day. This evolution in halo shape correlates well with the distribution of the infalling material: prolate configurations arise when haloes are fed through narrow filaments, which characterizes the early epochs of halo assembly, whereas triaxial/oblate configurations result as the accretion turns more isotropic at later times. Interestingly, at redshift z = 0, clear imprints of the past history of each halo are recorded in their shapes at different radii, which also exhibit a variation from prolate in the inner regions to triaxial/oblate in the outskirts. Provided that the Aquarius haloes are fair representatives of Milky Way-like 1012M☉ objects, we conclude that the shape of such dark matter haloes is a complex, time-dependent property, with each radial shell retaining memory of the conditions at the time of collapse.

  11. The Galaxy-Halo Connection in High-redshift Universe: Details and Evolution of Stellar-to-halo Mass Ratios of Lyman Break Galaxies on CFHTLS Deep Fields

    Science.gov (United States)

    Ishikawa, Shogo; Kashikawa, Nobunari; Toshikawa, Jun; Tanaka, Masayuki; Hamana, Takashi; Niino, Yuu; Ichikawa, Kohei; Uchiyama, Hisakazu

    2017-05-01

    We present the results of clustering analyses of Lyman break galaxies (LBGs) at z˜ 3, 4, and 5 using the final data release of the Canada-France-Hawaii Telescope Legacy Survey (CFHTLS). Deep- and wide-field images of the CFHTLS Deep Survey enable us to obtain sufficiently accurate two-point angular correlation functions to apply a halo occupation distribution analysis. The mean halo masses, calculated as ={10}11.7{--}{10}12.8 {h}-1 {M}⊙ , increase with the stellar-mass limit of LBGs. The threshold halo mass to have a central galaxy, {M}\\min , follows the same increasing trend as the low-z results, whereas the threshold halo mass to have a satellite galaxy, M 1, shows higher values at z=3{--}5 than z=0.5{--}1.5, over the entire stellar mass range. Satellite fractions of dropout galaxies, even at less massive halos, are found to drop sharply, from z = 2 down to less than 0.04, at z=3{--}5. These results suggest that satellite galaxies form inefficiently within dark halos at z=3{--}5, even for less massive satellites with {M}\\star pivot}, which is the halo mass at a peak in the star-formation efficiency, at 3 3. In addition, {M}{{h}}{pivot} and its normalization are found to be almost unchanged during 0< z< 5. Our study provides observational evidence that galaxy formation is ubiquitously most efficient near a halo mass of {M}{{h}}˜ {10}12 {M}⊙ over cosmic time.

  12. Simple Machine Junk Cars

    Science.gov (United States)

    Herald, Christine

    2010-01-01

    During the month of May, the author's eighth-grade physical science students study the six simple machines through hands-on activities, reading assignments, videos, and notes. At the end of the month, they can easily identify the six types of simple machine: inclined plane, wheel and axle, pulley, screw, wedge, and lever. To conclude this unit,…

  13. Simple Machines Made Simple.

    Science.gov (United States)

    St. Andre, Ralph E.

    Simple machines have become a lost point of study in elementary schools as teachers continue to have more material to cover. This manual provides hands-on, cooperative learning activities for grades three through eight concerning the six simple machines: wheel and axle, inclined plane, screw, pulley, wedge, and lever. Most activities can be…

  14. Perpetual Motion Machine

    Directory of Open Access Journals (Sweden)

    D. Tsaousis

    2008-01-01

    Full Text Available Ever since the first century A.D. there have been relative descriptions of known devices as well as manufactures for the creation of perpetual motion machines. Although physics has led, with two thermodynamic laws, to the opinion that a perpetual motion machine is impossible to be manufactured, inventors of every age and educational level appear to claim that they have invented something «entirely new» or they have improved somebody else’s invention, which «will function henceforth perpetually»! However the fact of the failure in manufacturing a perpetual motion machine till now, it does not mean that countless historical elements for these fictional machines become indifferent. The discussion on every version of a perpetual motion machine on the one hand gives the chance to comprehend the inventor’s of each period level of knowledge and his way of thinking, and on the other hand, to locate the points where this «perpetual motion machine» clashes with the laws of nature and that’s why it is impossible to have been manufactured or have functioned. The presentation of a new «perpetual motion machine» has excited our interest to locate its weak points. According to the designer of it the machine functions with the work produced by the buoyant force

  15. Human Machine Learning Symbiosis

    Science.gov (United States)

    Walsh, Kenneth R.; Hoque, Md Tamjidul; Williams, Kim H.

    2017-01-01

    Human Machine Learning Symbiosis is a cooperative system where both the human learner and the machine learner learn from each other to create an effective and efficient learning environment adapted to the needs of the human learner. Such a system can be used in online learning modules so that the modules adapt to each learner's learning state both…

  16. Semantics via Machine Translation

    Science.gov (United States)

    Culhane, P. T.

    1977-01-01

    Recent experiments in machine translation have given the semantic elements of collocation in Russian more objective criteria. Soviet linguists in search of semantic relationships have attempted to devise a semantic synthesis for construction of a basic language for machine translation. One such effort is summarized. (CHK)

  17. Machine Translation Project

    Science.gov (United States)

    Bajis, Katie

    1993-01-01

    The characteristics and capabilities of existing machine translation systems were examined and procurement recommendations were developed. Four systems, SYSTRAN, GLOBALINK, PC TRANSLATOR, and STYLUS, were determined to meet the NASA requirements for a machine translation system. Initially, four language pairs were selected for implementation. These are Russian-English, French-English, German-English, and Japanese-English.

  18. Approaches to Machine Learning.

    Science.gov (United States)

    Langley, Pat; Carbonell, Jaime G.

    1984-01-01

    Reviews approaches to machine learning (development of techniques to automate acquisition of new information, skills, and ways of organizing existing information) in symbolic domains. Four categorical tasks addressed in machine learning literature are examined: learning from examples, learning search heuristics, learning by observation, and…

  19. Reactive Turing machines

    NARCIS (Netherlands)

    J.C.M. Baeten (Jos); S.P. Luttik (Bas); P.J.A. van Tilburg

    2013-01-01

    textabstractWe propose reactive Turing machines (RTMs), extending classical Turing machines with a process-theoretical notion of interaction, and use it to define a notion of executable transition system. We show that every computable transition system with a bounded branching degree is simulated

  20. Machine learning with R

    CERN Document Server

    Lantz, Brett

    2015-01-01

    Perhaps you already know a bit about machine learning but have never used R, or perhaps you know a little R but are new to machine learning. In either case, this book will get you up and running quickly. It would be helpful to have a bit of familiarity with basic programming concepts, but no prior experience is required.

  1. Machining heavy plastic sections

    Science.gov (United States)

    Stalkup, O. M.

    1967-01-01

    Machining technique produces consistently satisfactory plane-parallel optical surfaces for pressure windows, made of plexiglass, required to support a photographic study of liquid rocket combustion processes. The surfaces are machined and polished to the required tolerances and show no degradation from stress relaxation over periods as long as 6 months.

  2. Stirling machine operating experience

    Energy Technology Data Exchange (ETDEWEB)

    Ross, B. [Stirling Technology Co., Richland, WA (United States); Dudenhoefer, J.E. [Lewis Research Center, Cleveland, OH (United States)

    1994-09-01

    Numerous Stirling machines have been built and operated, but the operating experience of these machines is not well known. It is important to examine this operating experience in detail, because it largely substantiates the claim that stirling machines are capable of reliable and lengthy operating lives. The amount of data that exists is impressive, considering that many of the machines that have been built are developmental machines intended to show proof of concept, and are not expected to operate for lengthy periods of time. Some Stirling machines (typically free-piston machines) achieve long life through non-contact bearings, while other Stirling machines (typically kinematic) have achieved long operating lives through regular seal and bearing replacements. In addition to engine and system testing, life testing of critical components is also considered. The record in this paper is not complete, due to the reluctance of some organizations to release operational data and because several organizations were not contacted. The authors intend to repeat this assessment in three years, hoping for even greater participation.

  3. Coordinate measuring machines

    DEFF Research Database (Denmark)

    De Chiffre, Leonardo

    This document is used in connection with three exercises of 2 hours duration as a part of the course GEOMETRICAL METROLOGY AND MACHINE TESTING. The exercises concern three aspects of coordinate measuring: 1) Measuring and verification of tolerances on coordinate measuring machines, 2) Traceabilit...

  4. Microsoft Azure machine learning

    CERN Document Server

    Mund, Sumit

    2015-01-01

    The book is intended for those who want to learn how to use Azure Machine Learning. Perhaps you already know a bit about Machine Learning, but have never used ML Studio in Azure; or perhaps you are an absolute newbie. In either case, this book will get you up-and-running quickly.

  5. LHC Report: machine development

    CERN Multimedia

    Rogelio Tomás García for the LHC team

    2015-01-01

    Machine development weeks are carefully planned in the LHC operation schedule to optimise and further study the performance of the machine. The first machine development session of Run 2 ended on Saturday, 25 July. Despite various hiccoughs, it allowed the operators to make great strides towards improving the long-term performance of the LHC.   The main goals of this first machine development (MD) week were to determine the minimum beam-spot size at the interaction points given existing optics and collimation constraints; to test new beam instrumentation; to evaluate the effectiveness of performing part of the beam-squeezing process during the energy ramp; and to explore the limits on the number of protons per bunch arising from the electromagnetic interactions with the accelerator environment and the other beam. Unfortunately, a series of events reduced the machine availability for studies to about 50%. The most critical issue was the recurrent trip of a sextupolar corrector circuit –...

  6. Micro-machining.

    Science.gov (United States)

    Brinksmeier, Ekkard; Preuss, Werner

    2012-08-28

    Manipulating bulk material at the atomic level is considered to be the domain of physics, chemistry and nanotechnology. However, precision engineering, especially micro-machining, has become a powerful tool for controlling the surface properties and sub-surface integrity of the optical, electronic and mechanical functional parts in a regime where continuum mechanics is left behind and the quantum nature of matter comes into play. The surprising subtlety of micro-machining results from the extraordinary precision of tools, machines and controls expanding into the nanometre range-a hundred times more precise than the wavelength of light. In this paper, we will outline the development of precision engineering, highlight modern achievements of ultra-precision machining and discuss the necessity of a deeper physical understanding of micro-machining.

  7. Sensitivity of the halo nuclei-12C elastic scattering at incident nucleon energy 800 MeV to the halo density distribution

    Science.gov (United States)

    Hassan, M. A. M.; Nour El-Din, M. S. M.; Ellithi, A.; Hosny, H.; Salama, T. N. E.

    2017-10-01

    In the framework of Glauber optical limit approximation where Coulomb effect is taken into account, the elastic scattering differential cross section for halo nuclei with {}^{12}{C} at 800 MeV/N has been calculated. Its sensitivity to the halo densities and the root mean square of the core and halo is the main goal of the current study. The projectile nuclei are taken to be one-neutron and two-neutron halo. The calculations are carried out for Gaussian-Gaussian, Gaussian-Oscillator and Gaussian-2 s phenomenological densities for each considered projectile in the mass number range 6-29. Also included a comparison between the obtained results of phenomenological densities and the results within the microscopic densities LSSM of {}6{He} and {}^{11}{Li} and microscopic densities GCM of {}^{11}{Be} where the density of the target nucleus {}^{12}{C} obtained from electron-{}^{12}{C} scattering is used. The zero range approximation is considered in the calculations. We found that the sensitivity of elastic scattering differential cross section to the halo density is clear if the nucleus appears as two clear different clusters, core and halo.

  8. Isobar analog states (IAS), double isobar analog states (DIAS), configuration states (CS), and double configuration states (DCS) in halo nuclei. Halo isomers

    Energy Technology Data Exchange (ETDEWEB)

    Izosimov, I. N., E-mail: izosimov@jinr.ru [Joint Institute for Nuclear Research, 141980 Dubna (Russian Federation)

    2015-10-15

    It has been shown that IAS, DIAS, CS, and DCS can simultaneously have n-n, n-p, and p-p halo components in their wave functions. Differences in halo structure of the excited and ground states can result in the formation of isomers (halo-isomers). Both the Borromean and tango halo types can be observed for n-p configurations of atomic nuclei. The structure of the ground and excited states with different isospin quantum number in halo like nuclei is discussed. B(Mλ) and B(Eλ) for γ-transitions in {sup 6,7,8}Li, {sup 8,9,10}Be, {sup 8,10,11}B, {sup 10,11,12,13,14}C, {sup 13,14,15,16,17}N, {sup 15,16,17,19}O, and {sup 17}F are analyzed. Special attention is given to nuclei whose ground state does not exhibit halo structure but the excited state may have one.

  9. The Splashback Radius of Halos from Particle Dynamics. I. The SPARTA Algorithm

    Science.gov (United States)

    Diemer, Benedikt

    2017-07-01

    Motivated by the recent proposal of the splashback radius as a physical boundary of dark-matter halos, we present a parallel computer code for Subhalo and PARticle Trajectory Analysis (Sparta). The code analyzes the orbits of all simulation particles in all host halos, billions of orbits in the case of typical cosmological N-body simulations. Within this general framework, we develop an algorithm that accurately extracts the location of the first apocenter of particles after infall into a halo, or splashback. We define the splashback radius of a halo as the smoothed average of the apocenter radii of individual particles. This definition allows us to reliably measure the splashback radii of 95% of host halos above a resolution limit of 1000 particles. We show that, on average, the splashback radius and mass are converged to better than 5% accuracy with respect to mass resolution, snapshot spacing, and all free parameters of the method.

  10. Transverse Beam Halo Measurements at High Intensity Neutrino Source (HINS) using Vibrating Wire Monitor

    Energy Technology Data Exchange (ETDEWEB)

    Chung, M.; Hanna, B.; Scarpine, V.; Shiltsev, V.; Steimel, J.; Artinian, S.; Arutunian, S.

    2015-02-26

    The measurement and control of beam halos will be critical for the applications of future high-intensity hadron linacs. In particular, beam profile monitors require a very high dynamic range when used for the transverse beam halo measurements. In this study, the Vibrating Wire Monitor (VWM) with aperture 60 mm was installed at the High Intensity Neutrino Source (HINS) front-end to measure the transverse beam halo. A vibrating wire is excited at its resonance frequency with the help of a magnetic feedback loop, and the vibrating and sensitive wires are connected through a balanced arm. The sensitive wire is moved into the beam halo region by a stepper motor controlled translational stage. We study the feasibility of the vibrating wire for the transverse beam halo measurements in the low-energy front-end of the proton linac.

  11. HaloTag protein-mediated specific labeling of living cells with quantum dots.

    Science.gov (United States)

    So, Min-kyung; Yao, Hequan; Rao, Jianghong

    2008-09-26

    Quantum dots emerge as an attractive alternative to small molecule fluorophores as fluorescent tags for in vivo cell labeling and imaging. This communication presents a method for specific labeling of live cells using quantum dots. The labeling is mediated by HaloTag protein expressed at the cell surface which forms a stable covalent adduct with its ligand (HaloTag ligand). The labeling can be performed in one single step with quantum dot conjugates that are functionalized with HaloTag ligand, or in two steps with biotinylated HaloTag ligand first and followed by streptavidin coated quantum dots. Live cell fluorescence imaging indicates that the labeling is specific and takes place at the cell surface. This HaloTag protein-mediated cell labeling method should facilitate the application of quantum dots for live cell imaging.

  12. Direct observations of the formation of the solar wind halo from the strahl

    Energy Technology Data Exchange (ETDEWEB)

    Gurgiolo, C. [Bitterroot Basic Research, Hamilton, MT (United States); Goldstein, M.L.; Vinas, A.F. [NASA Goddard Space Flight Center, Greenbelt, MD (United States). Geospace Science Lab.; Fazakerley, A.N. [Univ. College London, Holmbury St. Mary Dorking, Surrey (United Kingdom). Mullard Space Science Lab.

    2012-07-01

    Observations of a continual erosion of the strahl and build up of the halo with distance from the sun suggests that, at least in part, the halo may be formed as a result of scattering of the strahl. This hypothesis is supported in this paper by observation of intense scattering of strahl electrons, which gives rise to a proto-halo electron population. This population eventually merges into, or becomes the halo. The fact that observations of intense scattering of the strahl are not common implies that the formation of the halo may not be a continuous process, but one that occurs, in part, in bursts in regions where the conditions responsible for the scattering are optimum. (orig.)

  13. Halo Emission of the Cat's Eye Nebula, NGC 6543 Shock Excitation by Fast Stellar Winds

    Directory of Open Access Journals (Sweden)

    Siek Hyung

    2002-09-01

    Full Text Available Images taken with the Chandra X-ray telescope have for the the first time revealed the central, wind-driven, hot bubble (Chu et al. 2001, while Hubble Space Telescope (HST WFPC2 images of the Cat's Eye nebula, NGC 6543, show that the temperature of the halo region of angular radius ~ 20'', is much higher than that of the inner bright H II region. With the coupling of a photoionization calculation to a hydrodynamic simulation, we predict the observed [O III] line intensities of the halo region with the same O abundance as in the core H II region: oxygen abundance gradient does not appear to exist in the NGC 6543 inner halo. An interaction between a (leaky fast stellar wind and halo gas may cause the higher excitation temperatures in the halo region and the inner hot bubble region observed with the Chandra X-ray telescope.

  14. Halo Models of Large Scale Structure and Reliability of Cosmological N-Body Simulations

    Directory of Open Access Journals (Sweden)

    José Gaite

    2013-05-01

    Full Text Available Halo models of the large scale structure of the Universe are critically examined, focusing on the definition of halos as smooth distributions of cold dark matter. This definition is essentially based on the results of cosmological N-body simulations. By a careful analysis of the standard assumptions of halo models and N-body simulations and by taking into account previous studies of self-similarity of the cosmic web structure, we conclude that N-body cosmological simulations are not fully reliable in the range of scales where halos appear. Therefore, to have a consistent definition of halos is necessary either to define them as entities of arbitrary size with a grainy rather than smooth structure or to define their size in terms of small-scale baryonic physics.

  15. A Machine Learning Assisted, Label-free, Non-invasive Approach for Somatic Reprogramming in Induced Pluripotent Stem Cell Colony Formation Detection and Prediction.

    Science.gov (United States)

    Fan, Ke; Zhang, Sheng; Zhang, Ying; Lu, Jun; Holcombe, Mike; Zhang, Xiao

    2017-10-18

    During cellular reprogramming, the mesenchymal-to-epithelial transition is accompanied by changes in morphology, which occur prior to iPSC colony formation. The current approach for detecting morphological changes associated with reprogramming purely relies on human experiences, which involve intensive amounts of upfront training, human error with limited quality control and batch-to-batch variations. Here, we report a time-lapse-based bright-field imaging analysis system that allows us to implement a label-free, non-invasive approach to measure morphological dynamics. To automatically analyse and determine iPSC colony formation, a machine learning-based classification, segmentation, and statistical modelling system was developed to guide colony selection. The system can detect and monitor the earliest cellular texture changes after the induction of reprogramming in human somatic cells on day 7 from the 20-24 day process. Moreover, after determining the reprogramming process and iPSC colony formation quantitatively, a mathematical model was developed to statistically predict the best iPSC selection phase independent of any other resources. All the computational detection and prediction experiments were evaluated using a validation dataset, and biological verification was performed. These algorithm-detected colonies show no significant differences (Pearson Coefficient) in terms of their biological features compared to the manually processed colonies using standard molecular approaches.

  16. A.M.T. Machine Tools Limited

    National Research Council Canada - National Science Library

    2005-01-01

    Hydromat Inc. - Rotary Transfer Machines, Trunnion Machines, Automatic Bar Feeders Maschinenfabrik Heinrich Muller HMP - Rotary Swaging Machines, Wire Straightening and Cutting Machines Turmatic Systems Inc...

  17. 15 CFR 700.31 - Metalworking machines.

    Science.gov (United States)

    2010-01-01

    ... Drilling and tapping machines Electrical discharge, ultrasonic and chemical erosion machines Forging machinery and hammers Gear cutting and finishing machines Grinding machines Hydraulic and pneumatic presses...

  18. What Makes the Family of Barred Disc Galaxies So Rich: Damping Stellar Bars in Spinning Haloes

    Science.gov (United States)

    Collier, Angela; Shlosman, Isaac; Heller, Clayton

    2018-02-01

    We model and analyze the secular evolution of stellar bars in spinning dark matter (DM) haloes with the cosmological spin λ ˜ 0 - 0.09. Using high-resolution stellar and DM numerical simulations, we focus on angular momentum exchange between stellar discs and DM haloes of various axisymmetric shapes — spherical, oblate and prolate. We find that stellar bars experience a diverse evolution which is guided by the ability of parent haloes to absorb angular momentum, J, lost by the disc through the action of gravitational torques, resonant and non-resonant. We confirm that dynamical bar instability is accelerated via resonant J-transfer to the halo. Our main findings relate to the long-term, secular evolution of disc-halo systems: with an increasing λ, bars experience less growth and basically dissolve after they pass through vertical buckling instability. Specifically, with increasing λ, (1) The vertical buckling instability in stellar bars colludes with inability of the inner halo to absorb J — this emerges as the main factor weakening or destroying bars in spinning haloes; (2) Bars lose progressively less J, and their pattern speeds level off; (3) Bars are smaller, and for λ ≳ 0.06 cease their growth completely following buckling; (4) Bars in λ > 0.03 halos have ratio of corotation-to-bar radii, RCR/Rb > 2, and represent so-called slow bars without offset dust lanes. We provide a quantitative analysis of J-transfer in disc-halo systems, and explain the reasons for absence of growth in fast spinning haloes and its observational corollaries. We conclude that stellar bar evolution is substantially more complex than anticipated, and bars are not as resilient as has been considered so far.

  19. Pushing down the low-mass halo concentration frontier with the Lomonosov cosmological simulations

    Science.gov (United States)

    Pilipenko, Sergey V.; Sánchez-Conde, Miguel A.; Prada, Francisco; Yepes, Gustavo

    2017-12-01

    We introduce the Lomonosov suite of high-resolution N-body cosmological simulations covering a full box of size 32 h-1 Mpc with low-mass resolution particles (2 × 107 h-1 M⊙) and three zoom-in simulations of overdense, underdense and mean density regions at much higher particle resolution (4 × 104 h-1 M⊙). The main purpose of this simulation suite is to extend the concentration-mass relation of dark matter haloes down to masses below those typically available in large cosmological simulations. The three different density regions available at higher resolution provide a better understanding of the effect of the local environment on halo concentration, known to be potentially important for small simulation boxes and small halo masses. Yet, we find the correction to be small in comparison with the scatter of halo concentrations. We conclude that zoom simulations, despite their limited representativity of the volume of the Universe, can be effectively used for the measurement of halo concentrations at least at the halo masses probed by our simulations. In any case, after a precise characterization of this effect, we develop a robust technique to extrapolate the concentration values found in zoom simulations to larger volumes with greater accuracy. Altogether, Lomonosov provides a measure of the concentration-mass relation in the halo mass range 107-1010 h-1 M⊙ with superb halo statistics. This work represents a first important step to measure halo concentrations at intermediate, yet vastly unexplored halo mass scales, down to the smallest ones. All Lomonosov data and files are public for community's use.

  20. Mergers and mass accretion for infalling halos both end well outside cluster virial radii

    Energy Technology Data Exchange (ETDEWEB)

    Behroozi, Peter S.; Wechsler, Risa H.; Lu, Yu; Hahn, Oliver; Busha, Michael T.; Klypin, Anatoly; Primack, Joel R.

    2014-05-14

    We find that infalling dark matter halos (i.e., the progenitors of satellite halos) begin losing mass well outside the virial radius of their eventual host halos. The peak mass occurs at a range of clustercentric distances, with median and 68th percentile range of $1.8^{+2.3}_{-1.0} \\,R_\\mathrm{vir,host}$ for progenitors of z = 0 satellites. The peak circular velocity for infalling halos occurs at significantly larger distances ($3.7^{+3.3}_{-2.2} \\,R_\\mathrm{vir,host}$ at z = 0). This difference arises because different physical processes set peak circular velocity (typically, ~1:5 and larger mergers which cause transient circular velocity spikes) and peak mass (typically, smooth accretion) for infalling halos. We find that infalling halos also stop having significant mergers well before they enter the virial radius of their eventual hosts. Mergers larger than a 1:40 ratio in halo mass end for infalling halos at similar clustercentric distances (~1.9 R vir, host) as the end of overall mass accretion. However, mergers larger than 1:3 typically end for infalling halos at more than four virial radial away from their eventual hosts. This limits the ability of mergers to affect quenching and morphology changes in clusters. We also note that the transient spikes which set peak circular velocity may lead to issues with abundance matching on that parameter, including unphysical galaxy stellar mass growth profiles near clusters; we propose a simple observational test to check if a better halo proxy for galaxy stellar mass exists.

  1. ZOMG - II. Does the halo assembly history influence central galaxies and gas accretion?

    Science.gov (United States)

    Romano-Díaz, Emilio; Garaldi, Enrico; Borzyszkowski, Mikolaj; Porciani, Cristiano

    2017-08-01

    The growth rate and the internal dynamics of galaxy-sized dark-matter haloes depend on their location within the cosmic web. Haloes that sit at the nodes grow in mass till the present time and are dominated by radial orbits. Conversely, haloes embedded in prominent filaments do not change much in size and are dominated by tangential orbits. Using zoom hydrodynamical simulations including star formation and feedback, we study how gas accretes on to these different classes of objects, which, for simplicity, we dub 'accreting' and 'stalled' haloes. We find that all haloes get a fresh supply of newly accreted gas in their inner regions, although this slowly decreases with time, in particular for the stalled haloes. The inflow of new gas is always higher than (but comparable with) that of recycled material. Overall, the cold-gas fraction increases (decreases) with time for the accreting (stalled) haloes. In all cases, a stellar disc and a bulge form at the centre of the simulated haloes. The total stellar mass is in excellent agreement with expectations based on the abundance-matching technique. Many properties of the central galaxies do not seem to correlate with the large-scale environment in which the haloes reside. However, there are two notable exceptions that characterize stalled haloes with respect to their accreting counterparts: (I) The galaxy disc contains much older stellar populations. (II) Its vertical scaleheight is larger by a factor of 2 or more. This thickening is likely due to the heating of the long-lived discs by mergers and close flybys.

  2. Trends and variability of midlatitude stratospheric water vapour deduced from the re-evaluated Boulder balloon series and HALOE

    Directory of Open Access Journals (Sweden)

    M. Scherer

    2008-03-01

    Full Text Available This paper presents an updated trend analysis of water vapour in the lower midlatitude stratosphere from the Boulder balloon-borne NOAA frostpoint hygrometer measurements and from the Halogen Occulation Experiment (HALOE. Two corrections for instrumental bias are applied to homogenise the frostpoint data series, and a quality assessment of all soundings after 1991 is presented. Linear trend estimates based on the corrected data for the period 1980–2000 are up to 40% lower than previously reported. Vertically resolved trends and variability are calculated with a multi regression analysis including the quasi-biennal oscillation and equivalent latitude as explanatory variables. In the range of 380 to 640 K potential temperature (≈14 to 25 km, the frostpoint data from 1981 to 2006 show positive linear trends between 0.3±0.3 and 0.7±0.1%/yr. The same dataset shows trends between −0.2±0.3 and 1.0±0.3%/yr for the period 1992 to 2005. HALOE data over the same time period suggest negative trends ranging from −1.1±0.2 to −0.1±0.1%/yr. In the lower stratosphere, a rapid drop of water vapour is observed in 2000/2001 with little change since. At higher altitudes, the transition is more gradual, with slowly decreasing concentrations between 2001 and 2007. This pattern is consistent with a change induced by a drop of water concentrations at entry into the stratosphere. Previously noted differences in trends and variability between frostpoint and HALOE remain for the homogenised data. Due to uncertainties in reanalysis temperatures and stratospheric transport combined with uncertainties in observations, no quantitative inference about changes of water entering the stratosphere in the tropics could be made with the mid latitude measurements analysed here.

  3. Stochastic Distribution of Wear of Carbide Tools during Machining ...

    African Journals Online (AJOL)

    The increasing awareness of wear of carbide tools during machining operation has created doubts about the ability of this tool material to withstand stress and strain induced by the machining process. Manufacturers are beginning to question their dependence on carbide tools, seeing that they no longer meet their expected ...

  4. The basic anaesthesia machine

    Directory of Open Access Journals (Sweden)

    C L Gurudatt

    2013-01-01

    Full Text Available After WTG Morton′s first public demonstration in 1846 of use of ether as an anaesthetic agent, for many years anaesthesiologists did not require a machine to deliver anaesthesia to the patients. After the introduction of oxygen and nitrous oxide in the form of compressed gases in cylinders, there was a necessity for mounting these cylinders on a metal frame. This stimulated many people to attempt to construct the anaesthesia machine. HEG Boyle in the year 1917 modified the Gwathmey′s machine and this became popular as Boyle anaesthesia machine. Though a lot of changes have been made for the original Boyle machine still the basic structure remains the same. All the subsequent changes which have been brought are mainly to improve the safety of the patients. Knowing the details of the basic machine will make the trainee to understand the additional improvements. It is also important for every practicing anaesthesiologist to have a thorough knowledge of the basic anaesthesia machine for safe conduct of anaesthesia.

  5. Machine Learning and Radiology

    Science.gov (United States)

    Wang, Shijun; Summers, Ronald M.

    2012-01-01

    In this paper, we give a short introduction to machine learning and survey its applications in radiology. We focused on six categories of applications in radiology: medical image segmentation, registration, computer aided detection and diagnosis, brain function or activity analysis and neurological disease diagnosis from fMR images, content-based image retrieval systems for CT or MRI images, and text analysis of radiology reports using natural language processing (NLP) and natural language understanding (NLU). This survey shows that machine learning plays a key role in many radiology applications. Machine learning identifies complex patterns automatically and helps radiologists make intelligent decisions on radiology data such as conventional radiographs, CT, MRI, and PET images and radiology reports. In many applications, the performance of machine learning-based automatic detection and diagnosis systems has shown to be comparable to that of a well-trained and experienced radiologist. Technology development in machine learning and radiology will benefit from each other in the long run. Key contributions and common characteristics of machine learning techniques in radiology are discussed. We also discuss the problem of translating machine learning applications to the radiology clinical setting, including advantages and potential barriers. PMID:22465077

  6. A Universal Reactive Machine

    DEFF Research Database (Denmark)

    Andersen, Henrik Reif; Mørk, Simon; Sørensen, Morten U.

    1997-01-01

    Turing showed the existence of a model universal for the set of Turing machines in the sense that given an encoding of any Turing machine asinput the universal Turing machine simulates it. We introduce the concept of universality for reactive systems and construct a CCS processuniversal...... in the sense that, given an encoding of any CCS process, it behaves like this process up to weak bisimulation. This construction has arather non-constructive use of silent actions and we argue that this would be the case for any universal CCS process....

  7. Fundamentals of machine design

    CERN Document Server

    Karaszewski, Waldemar

    2011-01-01

    A forum of researchers, educators and engineers involved in various aspects of Machine Design provided the inspiration for this collection of peer-reviewed papers. The resultant dissemination of the latest research results, and the exchange of views concerning the future research directions to be taken in this field will make the work of immense value to all those having an interest in the topics covered. The book reflects the cooperative efforts made in seeking out the best strategies for effecting improvements in the quality and the reliability of machines and machine parts and for extending

  8. Machine Learning for Hackers

    CERN Document Server

    Conway, Drew

    2012-01-01

    If you're an experienced programmer interested in crunching data, this book will get you started with machine learning-a toolkit of algorithms that enables computers to train themselves to automate useful tasks. Authors Drew Conway and John Myles White help you understand machine learning and statistics tools through a series of hands-on case studies, instead of a traditional math-heavy presentation. Each chapter focuses on a specific problem in machine learning, such as classification, prediction, optimization, and recommendation. Using the R programming language, you'll learn how to analyz

  9. Gaussian optical Ising machines

    Science.gov (United States)

    Clements, William R.; Renema, Jelmer J.; Wen, Y. Henry; Chrzanowski, Helen M.; Kolthammer, W. Steven; Walmsley, Ian A.

    2017-10-01

    It has recently been shown that optical parametric oscillator (OPO) Ising machines, consisting of coupled optical pulses circulating in a cavity with parametric gain, can be used to probabilistically find low-energy states of Ising spin systems. In this work, we study optical Ising machines that operate under simplified Gaussian dynamics. We show that these dynamics are sufficient for reaching probabilities of success comparable to previous work. Based on this result, we propose modified optical Ising machines with simpler designs that do not use parametric gain yet achieve similar performance, thus suggesting a route to building much larger systems.

  10. Analysis of synchronous machines

    CERN Document Server

    Lipo, TA

    2012-01-01

    Analysis of Synchronous Machines, Second Edition is a thoroughly modern treatment of an old subject. Courses generally teach about synchronous machines by introducing the steady-state per phase equivalent circuit without a clear, thorough presentation of the source of this circuit representation, which is a crucial aspect. Taking a different approach, this book provides a deeper understanding of complex electromechanical drives. Focusing on the terminal rather than on the internal characteristics of machines, the book begins with the general concept of winding functions, describing the placeme

  11. Machine Tool Software

    Science.gov (United States)

    1988-01-01

    A NASA-developed software package has played a part in technical education of students who major in Mechanical Engineering Technology at William Rainey Harper College. Professor Hack has been using (APT) Automatically Programmed Tool Software since 1969 in his CAD/CAM Computer Aided Design and Manufacturing curriculum. Professor Hack teaches the use of APT programming languages for control of metal cutting machines. Machine tool instructions are geometry definitions written in APT Language to constitute a "part program." The part program is processed by the machine tool. CAD/CAM students go from writing a program to cutting steel in the course of a semester.

  12. Electromagnetic properties of the Beryllium-11 nucleus in Halo EFT

    Directory of Open Access Journals (Sweden)

    Hammer H.-W.

    2010-04-01

    Full Text Available We compute electromagnetic properties of the Beryllium-11 nucleus using an effective field theory that exploits the separation of scales in this halo system. We fix the parameters of the EFT from measured data on levels and scattering lengths in the 10Be plus neutron system. We then obtain predictions for the B(E1 strength of the 1/2+ to 1/2− transition in the 11Be nucleus. We also compute the charge radius of the ground state of 11Be. Agreement with experiment within the expected accuracy of a leading-order computation in this EFT is obtained. We also indicate how higher-order corrections that affect both s-wave and p-wave 10 Be-neutron interactions will affect our results.

  13. Ice crystal characterization in cirrus clouds: a sun-tracking camera system and automated detection algorithm for halo displays

    Directory of Open Access Journals (Sweden)

    L. Forster

    2017-07-01

    Full Text Available Halo displays in the sky contain valuable information about ice crystal shape and orientation: e.g., the 22° halo is produced by randomly oriented hexagonal prisms while parhelia (sundogs indicate oriented plates. HaloCam, a novel sun-tracking camera system for the automated observation of halo displays is presented. An initial visual evaluation of the frequency of halo displays for the ACCEPT (Analysis of the Composition of Clouds with Extended Polarization Techniques field campaign from October to mid-November 2014 showed that sundogs were observed more often than 22° halos. Thus, the majority of halo displays was produced by oriented ice crystals. During the campaign about 27 % of the cirrus clouds produced 22° halos, sundogs or upper tangent arcs. To evaluate the HaloCam observations collected from regular measurements in Munich between January 2014 and June 2016, an automated detection algorithm for 22° halos was developed, which can be extended to other halo types as well. This algorithm detected 22° halos about 2 % of the time for this dataset. The frequency of cirrus clouds during this time period was estimated by co-located ceilometer measurements using temperature thresholds of the cloud base. About 25 % of the detected cirrus clouds occurred together with a 22° halo, which implies that these clouds contained a certain fraction of smooth, hexagonal ice crystals. HaloCam observations complemented by radiative transfer simulations and measurements of aerosol and cirrus cloud optical thickness (AOT and COT provide a possibility to retrieve more detailed information about ice crystal roughness. This paper demonstrates the feasibility of a completely automated method to collect and evaluate a long-term database of halo observations and shows the potential to characterize ice crystal properties.

  14. Predicting weak lensing statistics from halo mass reconstructions - Final Paper

    Energy Technology Data Exchange (ETDEWEB)

    Everett, Spencer [SLAC National Accelerator Lab., Menlo Park, CA (United States)

    2015-08-20

    As dark matter does not absorb or emit light, its distribution in the universe must be inferred through indirect effects such as the gravitational lensing of distant galaxies. While most sources are only weakly lensed, the systematic alignment of background galaxies around a foreground lens can constrain the mass of the lens which is largely in the form of dark matter. In this paper, I have implemented a framework to reconstruct all of the mass along lines of sight using a best-case dark matter halo model in which the halo mass is known. This framework is then used to make predictions of the weak lensing of 3,240 generated source galaxies through a 324 arcmin² field of the Millennium Simulation. The lensed source ellipticities are characterized by the ellipticity-ellipticity and galaxy-mass correlation functions and compared to the same statistic for the intrinsic and ray-traced ellipticities. In the ellipticity-ellipticity correlation function, I and that the framework systematically under predicts the shear power by an average factor of 2.2 and fails to capture correlation from dark matter structure at scales larger than 1 arcminute. The model predicted galaxy-mass correlation function is in agreement with the ray-traced statistic from scales 0.2 to 0.7 arcminutes, but systematically underpredicts shear power at scales larger than 0.7 arcminutes by an average factor of 1.2. Optimization of the framework code has reduced the mean CPU time per lensing prediction by 70% to 24 ± 5 ms. Physical and computational shortcomings of the framework are discussed, as well as potential improvements for upcoming work.

  15. Structure of dark matter halos in warm dark matter models and in models with long-lived charged massive particles

    Energy Technology Data Exchange (ETDEWEB)

    Kamada, Ayuki; Yoshida, Naoki [Kavli Institute for the Physics and Mathematics of the Universe, University of Tokyo, Kashiwa, Chiba 277-8583 (Japan); Kohri, Kazunori [Cosmophysics Group, Theory Center, IPNS, KEK, Tsukuba, 305-0801 (Japan); Takahashi, Tomo, E-mail: ayuki.kamada@ipmu.jp, E-mail: naoki.yoshida@phys.s.u-tokyo.ac.jp, E-mail: kohri@post.kek.jp, E-mail: tomot@cc.saga-u.ac.jp [Department of Physics, Saga University, Saga 840-8502 (Japan)

    2013-03-01

    We study the formation of non-linear structures in warm dark matter (WDM) models and in a long-lived charged massive particle (CHAMP) model. CHAMPs with a decay lifetime of about 1 yr induce characteristic suppression in the matter power spectrum at subgalactic scales through acoustic oscillations in the thermal background. We explore structure formation in such a model. We also study three WDM models, where the dark matter particles are produced through the following mechanisms: i) WDM particles are produced in the thermal background and then kinematically decoupled; ii) WDM particles are fermions produced by the decay of thermal heavy bosons; and iii) WDM particles are produced by the decay of non-relativistic heavy particles. We show that the linear matter power spectra for the three models are all characterised by the comoving Jeans scale at the matter-radiation equality. Furthermore, we can also describe the linear matter power spectrum for the long-lived CHAMP model in terms of a suitably defined characteristic cut-off scale k{sub Ch}, similarly to the WDM models. We perform large cosmological N-body simulations to study the non-linear growth of structures in these four models. We compare the halo mass functions, the subhalo mass functions, and the radial distributions of subhalos in simulated Milky Way-size halos. For the characteristic cut-off scale k{sub cut} = 51 h Mpc{sup −1}, the subhalo abundance ( ∼ 10{sup 9}M{sub sun}) is suppressed by a factor of ∼ 10 compared with the standard ΛCDM model. We then study the models with k{sub cut} ≅ 51, 410, 820 h Mpc{sup −1}, and confirm that the halo and the subhalo abundances and the radial distributions of subhalos are indeed similar between the different WDM models and the long-lived CHAMP model. The result suggests that the cut-off scale k{sub cut} not only characterises the linear power spectra but also can be used to predict the non-linear clustering properties. The radial distribution of subhalos

  16. Mechatronic design of a reconfigurable machining machine

    CSIR Research Space (South Africa)

    Xing, B

    2008-10-01

    Full Text Available can be applied to the design of RMM [4]. Researchers at the Carnegie Mellon University developed RMMS (Reconfigurable Modular Manipulator System) [5]. They identified the characteristics of reconfigurable machine design as a task based design... and developed a design methodology for reconfigurable manipulators from the kinematics task requirements [6] [7]. I.-M. Chen [8] applied the theory of graphs to the design of reconfigurable manipulators and proposed the concept of Assembly Incident Matrix...

  17. Introduction to AC machine design

    CERN Document Server

    Lipo, Thomas A

    2018-01-01

    AC electrical machine design is a key skill set for developing competitive electric motors and generators for applications in industry, aerospace, and defense. This book presents a thorough treatment of AC machine design, starting from basic electromagnetic principles and continuing through the various design aspects of an induction machine. Introduction to AC Machine Design includes one chapter each on the design of permanent magnet machines, synchronous machines, and thermal design. It also offers a basic treatment of the use of finite elements to compute the magnetic field within a machine without interfering with the initial comprehension of the core subject matter. Based on the author's notes, as well as after years of classroom instruction, Introduction to AC Machine Design: * Brings to light more advanced principles of machine design--not just the basic principles of AC and DC machine behavior * Introduces electrical machine design to neophytes while also being a resource for experienced designers * ...

  18. On the Evolution of Dark Matter Halo Properties Following Major and Minor Mergers

    Science.gov (United States)

    Wu, Peter; Zhang, Shawn; Lee, Christoph; Primack, Joel

    2018-01-01

    We conducted an analysis on dark matter halo properties following major and minor mergers to advance our understanding of halo evolution. In this work, we analyzed ~80,000 dark matter halos from the Bolshoi-Planck cosmological simulation and studied halo evolution during relaxation after major mergers. We then applied a Gaussian filter to the property evolutions and characterized peak distributions, frequencies, and variabilities for several halo properties, including centering, spin, shape (prolateness), scale radius, and virial ratio. However, there were also halos that experienced relaxation without the presence of major mergers. We hypothesized that this was due to minor mergers unrecorded by the simulation analysis. By using property peaks to create a novel merger detection algorithm, we attempted to find minor mergers and match them to the unaccounted relaxed halos. Not only did we find evidence that minor mergers were the causes, but we also found similarities between major and minor merger effects, showing the significance of minor mergers for future studies. Through our dark matter merger statistics, we expect our work to ultimately serve as vital parameters towards better understanding galaxy formation and evolution. Most of this work was carried out by high school students working under the auspices of the Science Internship Program (SIP) at UC Santa Cruz.

  19. Relation between halo spin and cosmic-web filaments at z ≃ 3

    Science.gov (United States)

    González, Roberto E.; Prieto, Joaquin; Padilla, Nelson; Jimenez, Raul

    2017-02-01

    We investigate the spin evolution of dark matter haloes and their dependence on the number of connected filaments from the cosmic web at high redshift (spin-filament relation hereafter). To this purpose, we have simulated 5000 haloes in the mass range 5 × 109 h-1 M⊙ to 5 × 1011 h-1 M⊙ at z = 3 in cosmological N-body simulations. We confirm the relation found by Prieto et al. (2015) where haloes with fewer filaments have larger spin. We also found that this relation is more significant for higher halo masses, and for haloes with a passive (no major mergers) assembly history. Another finding is that haloes with larger spin or with fewer filaments have their filaments more perpendicularly aligned with the spin vector. Our results point to a picture in which the initial spin of haloes is well described by tidal torque theory and then gets subsequently modified in a predictable way because of the topology of the cosmic web, which in turn is given by the currently favoured Lambda cold dark matter (LCDM) model. Our spin-filament relation is a prediction from LCDM that could be tested with observations.

  20. The HaloTag: Improving Soluble Expression and Applications in Protein Functional Analysis.

    Science.gov (United States)

    N Peterson, Scott; Kwon, Keehwan

    2012-01-01

    Technological and methodological advances have been critical for the rapidly evolving field of proteomics. The development of fusion tag systems is essential for purification and analysis of recombinant proteins. The HaloTag is a 34 KDa monomeric protein derived from a bacterial haloalkane dehalogenase. The majority of fusion tags in use today utilize a reversible binding interaction with a specific ligand. The HaloTag system is unique in that it forms a covalent linkage to its chloroalkane ligand. This linkage permits attachment of the HaloTag to a variety of functional reporters, which can be used to label and immobilize recombinant proteins. The success rate for HaloTag expression of soluble proteins is very high and comparable to maltose binding protein (MBP) tag. Furthermore, cleavage of the HaloTag does not result in protein insolubility that often is observed with the MBP tag. In the present report, we describe applications of the HaloTag system in our ongoing investigation of protein-protein interactions of the Y. pestis Type 3 secretion system on a custom protein microarray. We also describe the utilization of affinity purification/mass spectroscopy (AP/MS) to evaluate the utility of the Halo Tag system to characterize DNA binding activity and protein specificity.

  1. High Angular Momentum Halo Gas: A Feedback and Code-independent Prediction of LCDM

    Science.gov (United States)

    Stewart, Kyle R.; Maller, Ariyeh H.; Oñorbe, Jose; Bullock, James S.; Joung, M. Ryan; Devriendt, Julien; Ceverino, Daniel; Kereš, Dušan; Hopkins, Philip F.; Faucher-Giguère, Claude-André

    2017-07-01

    We investigate angular momentum acquisition in Milky Way-sized galaxies by comparing five high resolution zoom-in simulations, each implementing identical cosmological initial conditions but utilizing different hydrodynamic codes: Enzo, Art, Ramses, Arepo, and Gizmo-PSPH. Each code implements a distinct set of feedback and star formation prescriptions. We find that while many galaxy and halo properties vary between the different codes (and feedback prescriptions), there is qualitative agreement on the process of angular momentum acquisition in the galaxy’s halo. In all simulations, cold filamentary gas accretion to the halo results in ˜4 times more specific angular momentum in cold halo gas (λ cold ≳ 0.1) than in the dark matter halo. At z > 1, this inflow takes the form of inspiraling cold streams that are co-directional in the halo of the galaxy and are fueled, aligned, and kinematically connected to filamentary gas infall along the cosmic web. Due to the qualitative agreement among disparate simulations, we conclude that the buildup of high angular momentum halo gas and the presence of these inspiraling cold streams are robust predictions of Lambda Cold Dark Matter galaxy formation, though the detailed morphology of these streams is significantly less certain. A growing body of observational evidence suggests that this process is borne out in the real universe.

  2. High Angular Momentum Halo Gas: A Feedback and Code-independent Prediction of LCDM

    Energy Technology Data Exchange (ETDEWEB)

    Stewart, Kyle R. [Department of Mathematical Sciences, California Baptist University, 8432 Magnolia Ave., Riverside, CA 92504 (United States); Maller, Ariyeh H. [Department of Physics, New York City College of Technology, 300 Jay St., Brooklyn, NY 11201 (United States); Oñorbe, Jose [Max-Planck-Institut für Astronomie, Königstuhl 17, D-69117 Heidelberg (Germany); Bullock, James S. [Center for Cosmology, Department of Physics and Astronomy, The University of California at Irvine, Irvine, CA 92697 (United States); Joung, M. Ryan [Department of Astronomy, Columbia University, New York, NY 10027 (United States); Devriendt, Julien [Department of Physics, University of Oxford, The Denys Wilkinson Building, Keble Rd., Oxford OX1 3RH (United Kingdom); Ceverino, Daniel [Zentrum für Astronomie der Universität Heidelberg, Institut für Theoretische Astrophysik, Albert-Ueberle-Str. 2, D-69120 Heidelberg (Germany); Kereš, Dušan [Department of Physics, Center for Astrophysics and Space Sciences, University of California at San Diego, 9500 Gilman Dr., La Jolla, CA 92093 (United States); Hopkins, Philip F. [California Institute of Technology, 1200 E. California Blvd., Pasadena, CA 91125 (United States); Faucher-Giguère, Claude-André [Department of Physics and Astronomy and CIERA, Northwestern University, 2145 Sheridan Rd., Evanston, IL 60208 (United States)

    2017-07-01

    We investigate angular momentum acquisition in Milky Way-sized galaxies by comparing five high resolution zoom-in simulations, each implementing identical cosmological initial conditions but utilizing different hydrodynamic codes: Enzo, Art, Ramses, Arepo, and Gizmo-PSPH. Each code implements a distinct set of feedback and star formation prescriptions. We find that while many galaxy and halo properties vary between the different codes (and feedback prescriptions), there is qualitative agreement on the process of angular momentum acquisition in the galaxy’s halo. In all simulations, cold filamentary gas accretion to the halo results in ∼4 times more specific angular momentum in cold halo gas ( λ {sub cold} ≳ 0.1) than in the dark matter halo. At z > 1, this inflow takes the form of inspiraling cold streams that are co-directional in the halo of the galaxy and are fueled, aligned, and kinematically connected to filamentary gas infall along the cosmic web. Due to the qualitative agreement among disparate simulations, we conclude that the buildup of high angular momentum halo gas and the presence of these inspiraling cold streams are robust predictions of Lambda Cold Dark Matter galaxy formation, though the detailed morphology of these streams is significantly less certain. A growing body of observational evidence suggests that this process is borne out in the real universe.

  3. Molecular Machines: Nanoscale gadgets

    Science.gov (United States)

    Garcia-Garibay, Miguel A.

    2008-06-01

    Meeting their biological counterparts halfway, artificial molecular machines embedded in liquid crystals, crystalline solids and mesoporous materials are poised to meet the demands of the next generation of functional materials.

  4. Machine Vision Handbook

    CERN Document Server

    2012-01-01

    The automation of visual inspection is becoming more and more important in modern industry as a consistent, reliable means of judging the quality of raw materials and manufactured goods . The Machine Vision Handbook  equips the reader with the practical details required to engineer integrated mechanical-optical-electronic-software systems. Machine vision is first set in the context of basic information on light, natural vision, colour sensing and optics. The physical apparatus required for mechanized image capture – lenses, cameras, scanners and light sources – are discussed followed by detailed treatment of various image-processing methods including an introduction to the QT image processing system. QT is unique to this book, and provides an example of a practical machine vision system along with extensive libraries of useful commands, functions and images which can be implemented by the reader. The main text of the book is completed by studies of a wide variety of applications of machine vision in insp...

  5. Some relations between quantum Turing machines and Turing machines

    OpenAIRE

    Sicard, Andrés; Vélez, Mario

    1999-01-01

    For quantum Turing machines we present three elements: Its components, its time evolution operator and its local transition function. The components are related with the components of deterministic Turing machines, the time evolution operator is related with the evolution of reversible Turing machines and the local transition function is related with the transition function of probabilistic and reversible Turing machines.

  6. Magnetic equivalent circuit model for unipolar hybrid excitation synchronous machine

    Directory of Open Access Journals (Sweden)

    Kupiec Emil

    2015-03-01

    Full Text Available Lately, there has been increased interest in hybrid excitation electrical machines. Hybrid excitation is a construction that combines permanent magnet excitation with wound field excitation. Within the general classification, these machines can be classified as modified synchronous machines or inductor machines. These machines may be applied as motors and generators. The complexity of electromagnetic phenomena which occur as a result of coupling of magnetic fluxes of separate excitation systems with perpendicular magnetic axis is a motivation to formulate various mathematical models of these machines. The presented paper discusses the construction of a unipolar hybrid excitation synchronous machine. The magnetic equivalent circuit model including nonlinear magnetization curves is presented. Based on this model, it is possible to determine the multi-parameter relationships between the induced voltage and magnetomotive force in the excitation winding. Particular attention has been paid to the analysis of the impact of additional stator and rotor yokes on above relationship. Induced voltage determines the remaining operating parameters of the machine, both in the motor and generator mode of operation. The analysis of chosen correlations results in an identification of the effective control range of electromotive force of the machine.

  7. Are ancient dwarf satellites the building blocks of the Galactic halo?

    Science.gov (United States)

    Spitoni, E.; Vincenzo, F.; Matteucci, F.; Romano, D.

    2016-05-01

    According to the current cosmological cold dark matter paradigm, the Galactic halo could have been the result of the assemblage of smaller structures. Here we explore the hypothesis that the classical and ultra-faint dwarf spheroidal satellites of the Milky Way have been the building blocks of the Galactic halo by comparing their [α/Fe] and [Ba/Fe] versus [Fe/H] patterns with the ones observed in Galactic halo stars. The α elements deviate substantially from the observed abundances in the Galactic halo stars for [Fe/H] values larger than -2 dex, while they overlap for lower metallicities. On the other hand, for the [Ba/Fe] ratio, the discrepancy is extended at all [Fe/H] values, suggesting that the majority of stars in the halo are likely to have been formed in situ. Therefore, we suggest that [Ba/Fe] ratios are a better diagnostic than [α/Fe] ratios. Moreover, for the first time we consider the effects of an enriched infall of gas with the same chemical abundances as the matter ejected and/or stripped from dwarf satellites of the Milky Way on the chemical evolution of the Galactic halo. We find that the resulting chemical abundances of the halo stars depend on the assumed infall time-scale, and the presence of a threshold in the gas for star formation. In particular, in models with an infall time-scale for the halo around 0.8 Gyr coupled with a threshold in the surface gas density for the star formation (4 M⊙ pc-2), and the enriched infall from dwarf spheroidal satellites, the first halo stars formed show [Fe/H]>-2.4 dex. In this case, to explain [α/Fe] data for stars with [Fe/H]<-2.4 dex, we need stars formed in dSph systems.

  8. ELUCID. IV. Galaxy Quenching and its Relation to Halo Mass, Environment, and Assembly Bias

    Science.gov (United States)

    Wang, Huiyuan; Mo, H. J.; Chen, Sihan; Yang, Yang; Yang, Xiaohu; Wang, Enci; van den Bosch, Frank C.; Jing, Yipeng; Kang, Xi; Lin, Weipeng; Lim, S. H.; Huang, Shuiyao; Lu, Yi; Li, Shijie; Cui, Weiguang; Zhang, Youcai; Tweed, Dylan; Wei, Chengliang; Li, Guoliang; Shi, Feng

    2018-01-01

    We examine the quenched fraction of central and satellite galaxies as a function of galaxy stellar mass, halo mass, and the matter density of their large-scale environment. Matter densities are inferred from our ELUCID simulation, a constrained simulation of the local universe sampled by SDSS, while halo masses and central/satellite classification are taken from the galaxy group catalog of Yang et al. The quenched fraction for the total population increases systematically with the three quantities. We find that the “environmental quenching efficiency,” which quantifies the quenched fraction as a function of halo mass, is independent of stellar mass. And this independence is the origin of the stellar mass independence of density-based quenching efficiency found in previous studies. Considering centrals and satellites separately, we find that the two populations follow similar correlations of quenching efficiency with halo mass and stellar mass, suggesting that they have experienced similar quenching processes in their host halo. We demonstrate that satellite quenching alone cannot account for the environmental quenching efficiency of the total galaxy population, and that the difference between the two populations found previously arises mainly from the fact that centrals and satellites of the same stellar mass reside, on average, in halos of different mass. After removing these effects of halo mass and stellar mass, there remains a weak, but significant, residual dependence on environmental density, which is eliminated when halo assembly bias is taken into account. Our results therefore indicate that halo mass is the prime environmental parameter that regulates the quenching of both centrals and satellites.

  9. Galactic googly: the rotation-metallicity bias in the inner stellar halo of the Milky Way

    Science.gov (United States)

    Kafle, Prajwal R.; Sharma, Sanjib; Robotham, Aaron S. G.; Pradhan, Raj K.; Guglielmo, Magda; Davies, Luke J. M.; Driver, Simon P.

    2017-09-01

    The first and second moments of stellar velocities encode important information about the formation history of the Galactic halo. However, due to the lack of tangential motion and inaccurate distances of the halo stars, the velocity moments in the Galactic halo have largely remained 'known unknowns'. Fortunately, our off-centric position within the Galaxy allows us to estimate these moments in the galactocentric frame using the observed radial velocities of the stars alone. We use these velocities coupled with the hierarchical Bayesian scheme, which allows easy marginalization over the missing data (the proper motion, and uncertainty-free distance and line-of-sight velocity), to measure the velocity dispersions, orbital anisotropy (β) and streaming motion (vrot) of the halo main-sequence turn-off (MSTO) and K-giant (KG) stars in the inner stellar halo (r ≲ 15 kpc). We study the metallicity bias in kinematics of the halo stars and observe that the comparatively metal-rich ([Fe/H] > -1.4) and the metal-poor ([Fe/H] ≤ -1.4) MSTO samples show a clear systematic difference in vrot ∼ 20-40 km s - 1, depending on how restrictive the spatial cuts to cull the disc contamination are. The bias is also detected in KG samples but with less certainty. Both MSTO and KG populations suggest that the inner stellar halo of the Galaxy is radially biased i.e. σr > σθ or σϕ and β ≃ 0.5. The apparent metallicity contrariety in the rotation velocity among the halo sub-populations supports the co-existence of multiple populations in the galactic halo that may have formed through distinct formation scenarios, i.e. in situ versus accretion.

  10. Cosmic web alignments with the shape, angular momentum and peculiar velocities of dark matter haloes

    Science.gov (United States)

    Forero-Romero, Jaime E.; Contreras, Sergio; Padilla, Nelson

    2014-09-01

    We study the alignment of dark matter haloes with the cosmic web characterized by the tidal and velocity shear fields. We focus on the alignment of their shape, angular momentum and peculiar velocities. We use a cosmological N-body simulation that allows us to study dark matter haloes spanning almost five orders of magnitude in mass (109-1014) h-1 M⊙ and spatial scales of (0.5-1.0) h-1 Mpc to define the cosmic web. The strongest alignment is measured for halo shape along the smallest tidal eigenvector, e.g. along filaments and walls, with a signal that gets stronger as the halo mass increases. In the case of the velocity shear field only massive haloes >1012 h-1 M⊙ tend to have their shapes aligned along the largest tidal eigenvector, i.e. perpendicular to filaments and walls. For the angular momentum we find alignment signals only for haloes more massive than 1012 h-1 M⊙ both in the tidal and velocity shear fields where the preferences is to be parallel to the middle eigenvector; perpendicular to filaments and parallel to walls. Finally, the peculiar velocities show a strong alignment along the smallest tidal eigenvector for all halo masses; haloes move along filaments and walls. The same alignment is present with the velocity shear, albeit weaker and only for haloes less massive than 1012 h-1 M⊙. Our results show that the two different algorithms used to define the cosmic web describe different physical aspects of non-linear collapse and should be used in a complementary way to understand the cosmic web influence on galaxy evolution.

  11. Metalworking and machining fluids

    Science.gov (United States)

    Erdemir, Ali; Sykora, Frank; Dorbeck, Mark

    2010-10-12

    Improved boron-based metal working and machining fluids. Boric acid and boron-based additives that, when mixed with certain carrier fluids, such as water, cellulose and/or cellulose derivatives, polyhydric alcohol, polyalkylene glycol, polyvinyl alcohol, starch, dextrin, in solid and/or solvated forms result in improved metalworking and machining of metallic work pieces. Fluids manufactured with boric acid or boron-based additives effectively reduce friction, prevent galling and severe wear problems on cutting and forming tools.

  12. Human-machine interactions

    Science.gov (United States)

    Forsythe, J Chris [Sandia Park, NM; Xavier, Patrick G [Albuquerque, NM; Abbott, Robert G [Albuquerque, NM; Brannon, Nathan G [Albuquerque, NM; Bernard, Michael L [Tijeras, NM; Speed, Ann E [Albuquerque, NM

    2009-04-28

    Digital technology utilizing a cognitive model based on human naturalistic decision-making processes, including pattern recognition and episodic memory, can reduce the dependency of human-machine interactions on the abilities of a human user and can enable a machine to more closely emulate human-like responses. Such a cognitive model can enable digital technology to use cognitive capacities fundamental to human-like communication and cooperation to interact with humans.

  13. Exclusive measurement of breakup reactions with the one-neutron halo nucleus sup 1 sup 1 Be

    CERN Document Server

    Palit, R; Aumann, T; Boretzky, K; Carlson, B V; Cortina-Gil, D; Elze, T W; Emling, H; Geissel, H; Hellström, M; Jones, K L; Kratz, J V; Kulessa, R; Leifels, Y; Leistenschneider, A; Münzenberg, G; Nociforo, C; Reiter, P; Simon, H; Sümmerer, K; Walús, W

    2003-01-01

    Electromagnetic and nuclear inelastic scattering of the halo nucleus sup 1 sup 1 Be have been investigated by a measurement of the one-neutron removal channel, utilizing a secondary sup 1 sup 1 Be beam with an energy of 520 MeV/nucleon impinging on lead and carbon targets. All decay products, i.e. sup 1 sup 0 Be fragments, neutrons, and gamma-rays have been detected in coincidence. Partial cross sections for the population of ground and excited states in sup 1 sup 0 Be were determined for nuclear diffractive breakup as well as for electromagnetically induced breakup. The partial cross sections for ground-state transitions have been differentiated further with respect to excitation energy, and the dipole-strength function associated solely with transitions of the halo 2s sub 1 sub / sub 2 neutron to the continuum has been derived. The extracted dipole strength integrated from the neutron threshold up to 6.1 MeV excitation energy amounts to 0.90(6) e sup 2 fm sup 2. A spectroscopic factor for the nu 2s sub 1 su...

  14. Machine Protection Challenges for HL-LHC

    CERN Document Server

    Schmidt, R; Wenninger, J; Wollmann, D; Zerlauth, M

    2014-01-01

    LHC operation requires the flawless functioning of the machine protection systems. The energy stored in the beam was progressively increased beyond the 140 MJ range at the end of 2012 at 4 TeV/c. The further increase to more than 300 MJ expected for 2015 at 6.5 TeV/c should be possible with the existing protection systems. For HL-LHC additional failure modes need to be considered. The stored beam energy will increase by another factor of two with respect to nominal and a factor of five more than experienced so far. The maximum beta function in the high luminosity insertion regions will increase. It is planned to install crab cavities in the LHC to compensate for the loss in luminosity due to the crossing-angle. With crab cavities, sudden voltage decays within 100 µs after e.g. cavity quenches can lead to large transverse beam oscillations. Tracking simulations predict trajectory distortions of up to 1.5 σ after a sudden drop of the deflecting voltage in a single cavity. Protons in the halo with an energy of...

  15. First Observation of the LHC Beam Halo Using a Synchrotron Radiation Coronagraph

    OpenAIRE

    Mitsuhashi, Toshiyuki; Bravin, Enrico; Roncarolo, Federico; Trad, Georges

    2017-01-01

    A test coronagraph for the observation of beam halo has been installed in the Synchrotron radiation monitor line LHCB2 in 2015. This coronagraph is commissioned with LHC operation at 450GeV (injection energy). After some optical testing of the coronagraph with visible Synchrotron radiation in B2, we try to observe artificially-made beam halo. The beam halo of 10⁻³ order of magnitude against the beam core is excited by the kicker of the transverse damper. We have succeeded to observe a diffrac...

  16. SeNtInel 5P validaTion by Comet HALO

    OpenAIRE

    Fix, Andreas; Ehret, Gerhard; Bovensmann, Heinrich; Gerbig, Christoph; Pfeilsticker, K.; Zöger, Martin

    2015-01-01

    The goal of the proposed activity is the validation of the methane column of S5P using aircraft measurements. The airborne platform foreseen is the German research aircraft HALO. A dedicated HALO science mission that is focused on the measurement of methane (and carbon dioxide), dubbed CoMet, has been evaluated by the scientific steering committee of HALO and is now scheduled for the 1st half of 2017. In order to maximize gain, the team proposes to make use of the gathered data from this...

  17. Outflow vs. Infall in Spiral Galaxies: Metal Absorption in the Halo of NGC 891

    OpenAIRE

    Bregman, Joel N.; Miller, Eric D.; Seitzer, Patrick; Cowley, C. R.; Miller, Matthew J.

    2013-01-01

    Gas accreting onto a galaxy will be of low metallicity while halo gas due to a galactic fountain will be of near-solar metallicity. We test these predictions by measuring the metal absorption line properties of halo gas 5 kpc above the plane of the edge-on galaxy NGC 891, using observations taken with HST/STIS toward a bright background quasar. Metal absorption lines of Fe II, Mg II, and Mg I in the halo of NGC 891 are clearly seen, and when combined with recent deep H I observations, we are ...

  18. The dearth of halo dwarf galaxies: is there power on short scales?

    Science.gov (United States)

    Kamionkowski; Liddle

    2000-05-15

    N-body simulations of structure formation with scale-invariant primordial perturbations show significantly more virialized objects of dwarf-galaxy mass in a typical galactic halo than are observed around the Milky Way. We show that the dearth of observed dwarf galaxies could be explained by a dramatic downturn in the power spectrum at small distance scales. This suppression of small-scale power might also help mitigate the disagreement between cuspy simulated halos and smooth observed halos, while remaining consistent with Lyman-alpha-forest constraints on small-scale power. Such a spectrum could arise in inflationary models with broken-scale invariance.

  19. Evidence of lensing of the cosmic microwave background by dark matter halos.

    Science.gov (United States)

    Madhavacheril, Mathew; Sehgal, Neelima; Allison, Rupert; Battaglia, Nick; Bond, J Richard; Calabrese, Erminia; Caligiuri, Jerod; Coughlin, Kevin; Crichton, Devin; Datta, Rahul; Devlin, Mark J; Dunkley, Joanna; Dünner, Rolando; Fogarty, Kevin; Grace, Emily; Hajian, Amir; Hasselfield, Matthew; Hill, J Colin; Hilton, Matt; Hincks, Adam D; Hlozek, Renée; Hughes, John P; Kosowsky, Arthur; Louis, Thibaut; Lungu, Marius; McMahon, Jeff; Moodley, Kavilan; Munson, Charles; Naess, Sigurd; Nati, Federico; Newburgh, Laura; Niemack, Michael D; Page, Lyman A; Partridge, Bruce; Schmitt, Benjamin; Sherwin, Blake D; Sievers, Jon; Spergel, David N; Staggs, Suzanne T; Thornton, Robert; Van Engelen, Alexander; Ward, Jonathan T; Wollack, Edward J

    2015-04-17

    We present evidence of the gravitational lensing of the cosmic microwave background by 10(13) solar mass dark matter halos. Lensing convergence maps from the Atacama Cosmology Telescope Polarimeter (ACTPol) are stacked at the positions of around 12 000 optically selected CMASS galaxies from the SDSS-III/BOSS survey. The mean lensing signal is consistent with simulated dark matter halo profiles and is favored over a null signal at 3.2σ significance. This result demonstrates the potential of microwave background lensing to probe the dark matter distribution in galaxy group and galaxy cluster halos.

  20. Detecting the Disruption of Dark-Matter Halos with Stellar Streams.

    Science.gov (United States)

    Bovy, Jo

    2016-03-25

    Narrow stellar streams in the Milky Way halo are uniquely sensitive to dark-matter subhalos, but many of these subhalos may be tidally disrupted. I calculate the interaction between stellar and dark-matter streams using analytical and N-body calculations, showing that disrupting objects can be detected as low-concentration subhalos. Through this effect, we can constrain the lumpiness of the halo as well as the orbit and present position of individual dark-matter streams. This will have profound implications for the formation of halos and for direct- and indirect-detection dark-matter searches.