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Sample records for h1 detector recherche

  1. The H1 detector

    International Nuclear Information System (INIS)

    Cozzika, G.

    1992-11-01

    The H1 detector presently operating at the HERA e-p collider is described. A general overview of the detector is given with particular emphasis on the calorimeters, the main element of which is a liquid Argon calorimeter enclosed within a large radius solenoid. Calorimetry in the proton direction, close to the beam-pipe is provided by a copper-silicon pad hadronic calorimeter. In the electron direction a lead-scintillator electromagnetic calorimeter closes the solid angle between the rear part of the liquid Argon calorimeter and the beam-pipe. An iron limited streamer tube tail catcher using the return yoke of the solenoid as absorber completes the calorimetry of the detector. The hardware triggers derived from the calorimeters are also described and some performance details of the calorimeters are given

  2. Search for excited leptons at the HERA collider with the H1 detector; Recherche de leptons excites sur le collisionneur HERA avec le detecteur H1

    Energy Technology Data Exchange (ETDEWEB)

    Trinh, T.N

    2008-05-15

    The work presented in this Ph.D. thesis is a search for first generation excited leptons using the full data sample collected by the Hl detector installed on the HERA electron (positron)-proton collider. This study is motivated by theoretical approaches which extend the Standard Model by assuming the existence of lepton compositeness. The whole e{sup -}p and e{sup +}p collisions data collected by Hi from 1994 to 2007 and corresponding to a total integrated luminosity of 475 pb{sup -1} have been used for this analysis. The analysis of 13 different topologies was done, covering all the decay branching ratio of excited electrons (e*) and neutrinos ({nu}*). No evidence of the production of first generation excited leptons was observed. Exclusion limits on e* and {nu}* production cross section and on the coupling constant f/{lambda} as a function of the excited leptons mass are derived within gauge mediated models. The limit obtained extend the excluded region compared to previous excited lepton searches. For the first time at HERA, possible e* production via contact interactions is also studied. The e* production via contact and gauge productions together, including the interference between the two production modes, was considered. (author)

  3. The H1 silicon vertex detector

    International Nuclear Information System (INIS)

    Pitzl, D.; Behnke, O.; Biddulph, M.; Boesiger, K.; Eichler, R.; Erdmann, W.; Gabathuler, K.; Gassner, J.; Haynes, W.J..; Horisberger, R.; Kausch, M.; Lindstroem, M.; Niggli, H.; Noyes, G.; Pollet, P.; Steiner, S.; Streuli, S.; Szeker, K.; Truoel, P.

    2000-01-01

    The design, construction and performance of the H1 silicon vertex detector is described. It consists of two cylindrical layers of double-sided, double-metal silicon sensors read out by a custom designed analog pipeline chip. The analog signals are transmitted by optical fibres to a custom-designed ADC board and are reduced on PowerPC processors. Details of the design and construction are given and performance figures from the first data-taking periods are presented

  4. The readout system of the new H1 silicon detectors

    International Nuclear Information System (INIS)

    Buerger, J.; Hansen, K.; Lange, W.; Prell, S.; Zimmermann, W.; Henschel, H.; Haynes, W.J.; Noyes, G.W.; Joensson, L.; Gabathuler, K.; Horisberger, R.; Wagener, M.; Eichler, R.; Erdmann, W.; Niggli, H.; Pitzl, D.

    1995-03-01

    The H1 detector at HERA at DESY undergoes presently a major upgrade. In this context silicon strip detectors have been installed at beginning of 1995. The high bunch crossing frequency of HERA (10.4 MHz) demands a novel readout architecture which includes pipelining, signal processing and data reduction at a very early stage. The front end readout is hierarchically organized. The detector elements are read out by the APC chip which contains an analog pipeline and performs first background subtraction. Up to five readout chips are controlled by a Decoder Chip. The readout processor module (OnSiRoC) operates the detectors, controls the Decoder Chips and performs a first level data reduction. The paper describes the readout architecture of the H1 Silicon Detectors and performance data of the complete readout chain. (orig.)

  5. Development of the H1 backward silicon strip detector

    International Nuclear Information System (INIS)

    Eick, W.; Hansen, K.; Lange, W.; Prell, S.; Zimmermann, W.; Bullough, M.A.; Greenwood, N.M.; Lucas, A.D.; Newton, A.M.; Wilburn, C.D.; Horisberger, R.; Pitzl, D.; Haynes, W.J.; Noyes, G.

    1996-10-01

    The development and first results are described of a silicon strip detector telescope for the HERA experiment H1 designed to measure the polar angle of deep inelastic scattered electrons at small Bjorken x and low momentum transfers Q 2 . (orig.)

  6. Development of the H1 backward silicon strip detector

    International Nuclear Information System (INIS)

    Eick, W.; Hansen, K.; Lange, W.; Prell, S.; Zimmermann, W.; Bullough, M.A.; Greenwood, N.M.; Lucas, A.D.; Newton, A.M.; Wilburn, C.D.; Horisberger, R.; Pitzl, D.; Haynes, W.J.; Noyes, G.

    1997-01-01

    The development and first results are described of a silicon strip detector telescope for the HERA experiment H1 designed to measure the polar angle of deep inelastic scattered electrons at small Bjorken x and low momentum transfers Q 2 . (orig.)

  7. Beam tests of prototype fiber detectors for the H1 forward proton spectrometer

    International Nuclear Information System (INIS)

    Baehr, J.; Hiller, K.; Hoffmann, B.; Luedecke, H.; Menchikov, A.; Nahnhauer, R.; Roloff, H.E.; Tonisch, F.; Voelkert, R.

    1994-07-01

    Different prototypes of fiber detectors with an internal trigger system were tested in a 5 GeV electron beam at DESY. A silicon microstrip telescope was used for an external reference measurement of the beam to study the spatial resolution of the fiber detectors. On average 75% of all crossing electron tracks could be reconstructed with a precision better than 150 μm. These successful methodical investigations led to the installation of similar detectors in the proton beamline 81 m downstream of the central H1-detector at HERA as part of a forward proton spectrometer in spring 1994. (orig.)

  8. Beam tests of prototype fiber detectors for the H1 forward proton spectrometer

    International Nuclear Information System (INIS)

    Baehr, J.; Hiller, K.; Hoffmann, B.; Luedecke, H.; Menchikov, A.; Nahnhauer, R.; Roloff, H.E.; Tonisch, F.; Voelkert, R.

    1995-01-01

    Different prototypes of fiber detectors with an internal trigger system were tested in a 5 GeV electron beam at DESY. A silicon microstrip telescope was used for an external reference measurement of the beam to study the spatial resolution of the fiber detectors. On average 75% of all crossing electron tracks could be reconstructed with a precision better than 150 μm. These successful methodical investigations led to the installation of similar detectors in the proton beamline 81 m downstream of the central H1-detector at HERA as part of a forward proton spectrometer in spring 1994. (orig.)

  9. Track finding and fitting in the H1 Forward Track Detector

    International Nuclear Information System (INIS)

    Burke, S.; Henderson, R.C.W.; Maxfield, S.J.; Patel, G.D.; Morris, J.V.; Sankey, D.P.C.; Skillicorn, I.O.

    1995-07-01

    The tracking environment in the H1 Forward Tracker Detector, where the hit multiplicity from proton fragments is high, is parituclarly hostile. The techniques and software which have been developed for pattern recognition and Kalman fitting of charged particle tracks in this region are described in detail. (orig.)

  10. Measurement of the charm and beauty structure functions using the H1 vertex detector at HERA

    International Nuclear Information System (INIS)

    Aaron, F.D.; Alexa, C.; Preda, T.; Rotaru, M.; Stoicea, G.; Zus, R.; Aldaya Martin, M.; Alimujiang, K.; Antunovic, B.; Bartel, W.; Brandt, G.; Campbell, A.J.; Cholewa, A.; Deak, M.; Boer, Y. de; Eckerlin, G.; Elsen, E.; Felst, R.; Fischer, D.J.; Fleischer, M.; Gayler, J.; Glazov, A.; Gouzevitch, M.; Grell, B.R.; Haidt, D.; Helebrant, C.; Janssen, M.E.; Jung, H.; Katzy, J.; Kleinwort, C.; Knutsson, A.; Kraemer, M.; Krastev, K.; Kutak, K.; Levonian, S.; Lipka, K.; List, J.; Marti, L.; Meyer, A.B.; Meyer, H.; Meyer, J.; Michels, V.; Niebuhr, C.; Nikiforov, A.; Nozicka, M.; Olsson, J.E.; Panagoulias, I.; Papadopoulou, T.; Pitzl, D.; Placakyte, R.; Radescu, V.; Rurikova, Z.; Schmitt, S.; Schoeffel, L.; Sefkow, F.; Staykova, Z.; Steder, M.; Vargas Trevino, A.; Vinokurova, S.; Driesch, M. von den; Wissing, C.; Wuensch, E.; Andreev, V.; Belousov, A.; Eliseev, A.; Fomenko, A.; Gogitidze, N.; Lebedev, A.; Loktionova, N.; Malinovski, E.; Rusakov, S.; Shtarkov, L.N.; Soloviev, Y.; Vazdik, Y.; Asmone, A.; Stella, B.; Backovic, S.; Dubak, A.; Lastovicka-Medin, G.; Picuric, I.; Raicevic, N.; Baghdasaryan, A.; Ghazaryan, S.; Volchinski, V.; Zohrabyan, H.; Barrelet, E.; Begzsuren, K.; Ravdandorj, T.; Tseepeldorj, B.; Bizot, J.C.; Brisson, V.; Delcourt, B.; Jacquet, M.; Li, G.; Pascaud, C.; Tran, T.H.; Zhang, Z.; Zomer, F.; Boudry, V.; Moreau, F.; Specka, A.; Bozovic-Jelisavcic, I.; Mudrinic, M.; Pandurovic, M.; Smiljanic, I.; Bracinik, J.; Kenyon, I.R.; Newman, P.R.; Shaw-West, R.N.; Thompson, P.D.; Brinkmann, M.; Habib, S.; List, B.; Pokorny, B.; Toll, T.; Bruncko, D.; Cerny, V.; Ferencei, J.; Murin, P.; Tomasz, F.; Bunyatyan, A.; Buschhorn, G.; Chekelian, V.; Dossanov, A.; Grindhammer, G.; Kiesling, C.; Kogler, R.; Liptaj, A.; Olivier, B.; Raspiareza, A.; Shushkevich, S.; Bystritskaya, L.; Efremenko, V.; Fedotov, A.; Kropivnitskaya, A.; Lubimov, V.; Ozerov, D.; Petrukhin, A.; Rostovtsev, A.; Zhokin, A.; Cantun Avila, K.B.; Contreras, J.G.; Ruiz Tabasco, J.E.; Cassol-Brunner, F.; Diaconu, C.; Hoffmann, D.; Sauvan, E.; Trinh, T.N.; Vallee, C.; Cerny, K.; Pejchal, O.; Polifka, R.; Salek, D.; Valkarova, A.; Zacek, J.; Coughlan, J.A.; Morris, J.V.; Sankey, D.P.C.; Cozzika, G.; Feltesse, J.; Perez, E.; Cvach, J.; Reimer, P.; Zalesak, J.; Dainton, J.B.; Gabathuler, E.; Greenshaw, T.; Klein, M.; Kluge, T.; Kretzschmar, J.; Laycock, P.; Maxfield, S.J.; Mehta, A.; Patel, G.D.; Rahmat, A.J.; Daum, K.; Meyer, H.; Del Degan, M.; Grab, C.; Leibenguth, G.; Sauter, M.; Zimmermann, T.; Delvax, J.; Wolf, E.A. de; Favart, L.; Hreus, T.; Janssen, X.; Marage, P.; Mozer, M.U.; Roland, B.; Roosen, R.; Sunar, D.; Sykora, T.; Mechelen, P. van; Dodonov, V.; Lytkin, L.; Povh, B.; Egli, S.; Hildebrandt, M.; Horisberger, R.; Falkiewicz, A.; Goerlich, L.; Mikocki, S.; Milcewicz-Mika, I.; Nowak, G.; Sopicki, P.; Turnau, J.; Glushkov, I.; Henschel, H.; Hiller, K.H.; Kostka, P.; Lange, W.; Naumann, T.; Piec, S.; Henderson, R.C.W.; Sloan, T.; Hennekemper, E.; Herbst, M.; Jung, A.W.; Krueger, K.; Lendermann, V.; Schultz-Coulon, H.C.; Urban, K.; Herrera, G.; Lopez-Fernandez, R.; Joensson, L.; Osman, S.; Kapichine, M.; Makankine, A.; Morozov, A.; Palichik, V.; Spaskov, V.; Tchoulakov, V.; Landon, M.P.J.; Rizvi, E.; Thompson, G.; Traynor, D.; Martyn, H.U.; Mueller, K.; Nowak, K.; Robmann, P.; Straumann, U.; Truoel, P.; Schoening, A.; South, D.; Wegener, D.; Tsakov, I.

    2010-01-01

    Inclusive charm and beauty cross sections are measured in e - p and e + p neutral current collisions at HERA in the kinematic region of photon virtuality 5≤Q 2 ≤2000 GeV 2 and Bjorken scaling variable 0.0002≤x≤0.05. The data were collected with the H1 detector in the years 2006 and 2007 corresponding to an integrated luminosity of 189 pb -1 . The numbers of charm and beauty events are determined using variables reconstructed by the H1 vertex detector including the impact parameter of tracks to the primary vertex and the position of the secondary vertex. The measurements are combined with previous data and compared to QCD predictions. (orig.)

  11. Measurement of the Charm and Beauty Structure Functions using the H1 Vertex Detector at HERA

    CERN Document Server

    Aaron, FD; Alexa, C; Alimujiang, K; Andreev, V; Antunovic, B; Asmone, A; Backovic, S; Baghdasaryan, A; Barrelet, E; Bartel, W; Begzsuren, K; Belousov, A; Bizot, J C; Boudry, V; Bozovic-Jelisavcic, I; Bracinik, J; Brandt, G; Brinkmann, M; Brisson, V; Bruncko, D; Bunyatyan, A; Buschhorn, G; Bystritskaya, L; Campbell, A J; Cantun Avila, K B; Cassol-Brunner, F; Cerny, K; Cerny, V; Chekelian, V; Cholewa, A; Contreras, J G; Coughlan, J A; Cozzika, G; Cvach, J; Dainton, J B; Daum, K; Deak, M; de Boer, Y; Delcourt, B; Del Degan, M; Delvax, J; De Wolf, E A; Diaconu, C; Dodonov, V; Dossanov, A; Dubak, A; Eckerlin, G; Efremenko, V; Egli, S; Eliseev, A; Elsen, E; Falkiewicz, A; Favart, L; Fedotov, A; Felst, R; Feltesse, J; Ferencei, J; Fischer, D -J; Fleischer, M; Fomenko, A; Gabathuler, E; Gayler, J; Ghazaryan, Samvel; Glazov, A; Glushkov, I; Goerlich, L; Gogitidze, N; Gouzevitch, M; Grab, C; Greenshaw, T; Grell, B R; Grindhammer, G; Habib, S; Haidt, D; Helebrant, C; Henderson, R C W; Hennekemper, E; Henschel, H; Herbst, M; Herrera, G; Hildebrandt, M; Hiller, K H; Hoffmann, D; Horisberger, R; Hreus, T; Jacquet, M; Janssen, M E; Janssen, X; Jonsson, L; Jung, Andreas Werner; Jung, H; Kapichine, M; Katzy, J; Kenyon, I R; Kiesling, C; Klein, M; Kleinwort, C; Kluge, T; Knutsson, A; Kogler, R; Kostka, P; Kraemer, M; Krastev, K; Kretzschmar, J; Kropivnitskaya, A; Kruger, K; Kutak, K; Landon, M P J; Lange, W; Lastovicka-Medin, G; Laycock, P; Lebedev, A; Leibenguth, G; Lendermann, V; Levonian, S; Li, G; Lipka, K; Liptaj, A; List, B; List, J; Loktionova, N; Lopez-Fernandez, R; Lubimov, V; Lytkin, L; Makankine, A; Malinovski, E; Marage, P; Marti, Ll; Martyn, H -U; Maxfield, S J; Mehta, A; Meyer, A B; Meyer, H; Meyer, H; Meyer, J; Michels, V; Mikocki, S; Milcewicz-Mika, I; Moreau, F; Morozov, A; Morris, J V; Mozer, Matthias Ulrich; Mudrinic, M; Muller, K; Murin, P; Naumann, Th; Newman, P R; Niebuhr, C; Nikiforov, A; Nowak, G; Nowak, K; Nozicka, M; Olivier, B; Olsson, J E; Osman, S; Ozerov, D; Palichik, V; Panagoulias, I; Pandurovic, M; Papadopoulou, Th; Pascaud, C; Patel, G D; Pejchal, O; Perez, E; Petrukhin, A; Picuric, I; Piec, S; Pitzl, D; Placakyte, R; Pokorny, B; Polifka, R; Povh, B; Preda, T; Radescu, V; Rahmat, A J; Raicevic, N; Raspiareza, A; Ravdandorj, T; Reimer, P; Rizvi, E; Robmann, P; Roland, B; Roosen, R; Rostovtsev, A; Rotaru, M; Ruiz Tabasco, J E; Rurikova, Z; Rusakov, S; Salek, D; Sankey, D P C; Sauter, M; Sauvan, E; Schmitt, S; Schoeffel, L; Schoning, A; Schultz-Coulon, H -C; Sefkow, F; Shaw-West, R N; Shtarkov, L N; Shushkevich, S; Sloan, T; Smiljanic, Ivan; Soloviev, Y; Sopicki, P; South, D; Spaskov, V; Specka, Arnd E; Staykova, Z; Steder, M; Stella, B; Stoicea, G; Straumann, U; Sunar, D; Sykora, T; Tchoulakov, V; Thompson, G; Thompson, P D; Toll, T; Tomasz, F; Tran, T H; Traynor, D; Trinh, T N; Truol, P; Tsakov, I; Tseepeldorj, B; Turnau, J; Urban, K; Valkarova, A; Vallee, C; Van Mechelen, P; Vargas Trevino, A; Vazdik, Y; Vinokurova, S; Volchinski, V; von den Driesch, M; Wegener, D; Wissing, Ch; Wunsch, E; Zacek, J; Zalesak, J; Zhang, Z; Zhokin, A; Zimmermann, T; Zohrabyan, H; Zomer, F; Zus, R

    2010-01-01

    Inclusive charm and beauty cross sections are measured in e-p and e+p neutral current collisions at HERA in the kinematic region of photon virtuality 5H1 detector in the years 2006 and 2007 corresponding to an integrated luminosity of 189 pb^-1. The numbers of charm and beauty events are determined using variables reconstructed by the H1 vertex detector including the impact parameter of tracks to the primary vertex and the position of the secondary vertex. The measurements are combined with previous data and compared to QCD predictions.

  12. Measurement of D* meson with two jets in photoproduction with the H1 detector at HERA

    International Nuclear Information System (INIS)

    Staykova, Zlatka

    2011-02-01

    Photoproduction events containing a charmed meson D *± and two jets are investigated with the H1 detector using the HERA II data sample. The measurement is based on e + p collisions during the period of 2006/2007 data taking and uses integrated luminosity of 113.14 pb -1 . The kinematic range of the measurement covers 100 GeV γp 2 2 . The D * mesons are reconstructed in the decay channel, D *± →D 0 π ± →K -+ π ± π ± . Jets were reconstructed using the inclusive k t algorithm and are selected if they have transverse momenta of p t (jet)>3.5 GeV. One of the jets has to be associated with the D * meson itself, such that the parent charmed quark can be tagged. The phase space of the measurement is limited within the central rapidity for the D * meson and the D * jet , vertical stroke η vertical stroke <1.5 while the second jet was measured within, -1.5<η<2.9. Single differential cross sections and double differential distributions were measured and compared to Leading Order Monte Carlo (MC) event generators, Pythia and Cascade and with the Next-to-Leading order MC generator MC rate at NLO. (orig.)

  13. Study of charm quark fragmentation into D* mesons with the H1 detector at HERA II

    International Nuclear Information System (INIS)

    Liptaj, Andrej

    2008-12-01

    In this work charm quark fragmentation into D * mesons is investigated in deep-inelastic electron proton collisions. This work is based on data collected in the years 2004 - 2007 by the H1 detector at HERA, corresponding to a total integrated luminosity of 354.1 pb -1 . Three observables denoted z jet ,z hem and z hem (jet) are measured, each of them meant to approximate the momentum fraction of the charm quark transferred to the D * meson. In case of z jet the quark momentum is estimated as the momentum of the D * jet, for the two other observables it is approximated by the momentum of an appropriately chosen D * hemisphere. The visible range is defined by the phase space requirements on the DIS events: Q 2 > 5 GeV 2 , 0.05 *± particles: 1.5 GeV T (D * ) * ) vertical stroke T (D * jet) > 3.0 GeV enters the phase space definition in case of z jet and z hem (jet) , where a reconstructed jet containing the D * meson is required. Within this phase space the normalized single differential cross sections are measured in bins of the three observables. Two Monte Carlo models, RAPGAP and CASCADE, both interfaced with the PYTHIA program for the Lund string fragmentation, are used to make predictions of the respective cross sections for different parametrizations (Peterson and Kartvelishvili) of the charm fragmentation function. The difference in cross sections between data and Monte Carlo model predictions for different values of the fragmentation parameter is quantified by calculating values of χ 2 in order to extract optimal parameters for the Peterson and Kartvelishvili parametrization. Using predictions from PYTHIA for e + e - annihilation optimal parameters are extracted also from the published BELLE and ALEPH data. The obtained results show that the H1 data allow the determination of the fragmentation parameters with a precision which is of interest. The extracted parameters are however found to apparently depend on the charm quark production energy: the z hem

  14. Test of a liquid argon calorimeter for the H1-detector with investigations on compensation via software techniques

    International Nuclear Information System (INIS)

    Binder, E.

    1990-05-01

    In Summer '88 a pre-series model of the inner-forward-calorimeter for the H1-detector was tested using electrons and pions from a CERN test beam. The performance of the calorimeter was analysed, with emphasis on charge calibration, noise in the read-out chain, HV-curve, energy calibration and longitudinal shower shape. A special study was done on software techniques to achieve compensation (ε/h = 1) for a non-compensating calorimeter exploiting the fine granularity of the device to spot electromagnetic energy deposits. (orig.) [de

  15. Measurement of Beauty Photoproduction near Threshold using Di-electron Events with the H1 Detector at HERA

    CERN Document Server

    Aaron, F.D.; Andreev, V.; Backovic, S.; Baghdasaryan, A.; Baghdasaryan, S.; Barrelet, E.; Bartel, W.; Begzsuren, K.; Belousov, A.; Belov, P.; Bizot, J.C.; Boudry, V.; Bozovic-Jelisavcic, I.; Bracinik, J.; Brandt, G.; Brinkmann, M.; Brisson, V.; Britzger, D.; Bruncko, D.; Bunyatyan, A.; Bylinkin, A.; Bystritskaya, L.; Campbell, A.J.; Cantun Avila, K.B.; Ceccopieri, F.; Cerny, K.; Cerny, V.; Chekelian, V.; Contreras, J.G.; Coughlan, J.A.; Cvach, J.; Dainton, J.B.; Daum, K.; Delcourt, B.; Delvax, J.; De Wolf, E.A.; Diaconu, C.; Dobre, M.; Dodonov, V.; Dossanov, A.; Dubak, A.; Eckerlin, G.; Egli, S.; Eliseev, A.; Elsen, E.; Favart, L.; Fedotov, A.; Felst, R.; Feltesse, J.; Ferencei, J.; Fischer, D.J.; Fleischer, M.; Fomenko, A.; Gabathuler, E.; Gayler, J.; Ghazaryan, S.; Glazov, A.; Goerlich, L.; Gogitidze, N.; Gouzevitch, M.; Grab, C.; Grebenyuk, A.; Greenshaw, T.; Grindhammer, G.; Habib, S.; Haidt, D.; Henderson, R.C.W.; Hennekemper, E.; Henschel, H.; Herbst, M.; Herrera, G.; Hildebrandt, M.; Hiller, K.H.; Hoffmann, D.; Horisberger, R.; Hreus, T.; Huber, F.; Jacquet, M.; Janssen, X.; Jonsson, L.; Jung, A.W.; Jung, H.; Kapichine, M.; Kenyon, I.R.; Kiesling, C.; Klein, M.; Kleinwort, C.; Kogler, R.; Kostka, P.; Kramer, M.; Kretzschmar, J.; Kruger, K.; Landon, M.P.J.; Lange, W.; Lastovicka-Medin, G.; Laycock, P.; Lebedev, A.; Lendermann, V.; Levonian, S.; Lipka, K.; List, B.; List, J.; Lobodzinski, B.; Lopez-Fernandez, R.; Lubimov, V.; Malinovski, E.; Martyn, H.U.; Maxfield, S.J.; Mehta, A.; Meyer, A.B.; Meyer, H.; Meyer, J.; Mikocki, S.; Milcewicz-Mika, I.; Moreau, F.; Morozov, A.; Morris, J.V.; Muller, K.; Naumann, Th.; Newman, P.R.; Niebuhr, C.; Nikitin, D.; Nowak, G.; Nowak, K.; Olivier, B.; Olsson, J.E.; Ozerov, D.; Pahl, P.; Palichik, V.; Pandurovic, M.; Pascaud, C.; Patel, G.D.; Perez, E.; Petrukhin, A.; Picuric, I.; Pirumov, H.; Pitzl, D.; Placakyte, R.; Pokorny, B.; Polifka, R.; Povh, B.; Radescu, V.; Raicevic, N.; Ravdandorj, T.; Reimer, P.; Rizvi, E.; Robmann, P.; Roosen, R.; Rostovtsev, A.; Rotaru, M.; Ruiz Tabasco, J.E.; Rusakov, S.; Salek, D.; Sankey, D.P.C.; Sauter, M.; Sauvan, E.; Schmitt, S.; Schoeffel, L.; Schoning, A.; Schultz-Coulon, H.C.; Sefkow, F.; Shtarkov, L.N.; Shushkevich, S.; Sloan, T.; Soloviev, Y.; Sopicki, P.; South, D.; Spaskov, V.; Specka, A.; Staykova, Z.; Steder, M.; Stella, B.; Stoicea, G.; Straumann, U.; Sykora, T.; Thompson, P.D.; Tran, T.H.; Traynor, D.; Truol, P.; Tsakov, I.; Tseepeldorj, B.; Turnau, J.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Vazdik, Y.; Wegener, D.; Wunsch, E.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhokin, A.; Zlebcik, R.; Zohrabyan, H.; Zomer, F.

    2012-10-03

    The cross section for ep -> e b\\bar{b} X in photoproduction is measured with the H1 detector at the ep-collider HERA. The decay channel b\\bar{b} -> ee X' is selected by identifying the semi-electronic decays of the b-quarks. The total production cross section is measured in the kinematic range given by the photon virtuality Q^2 down to the threshold. The results are compared to next-to-leading-order QCD predictions.

  16. Measurement of beauty photoproduction at threshold using di-electron events with the H1 detector at HERA

    International Nuclear Information System (INIS)

    Sauter, Michel David

    2009-12-01

    The cross section of b anti b photoproduction in ep collisions has been measured with the H1 detector at HERA. Events containing b-quarks were identified through detection of two low momentum electrons in the nal state. Semileptonic decays b anti b→eeX were exploited in the kinematic range of the photon virtuality Q 2 2 , the inelasticity 0.2 T -electron identification. (orig.)

  17. Search for excited leptons in the data of the H1 experiment at the HERA collider; Recherche de leptons excites dans les donnees de l'experience H1 aupres du collisionneur HERA

    Energy Technology Data Exchange (ETDEWEB)

    Delerue, N

    2002-05-01

    Composite models are one of the possible extensions of the Standard Model. One of their implications, at the energy in the reach of present particles accelerators, would be the excitation of leptons. This PhD. thesis describes the search for excited leptons with the H1 detector installed on the electron-proton collider HERA in Hamburg (Germany). The data used were accumulated between 1994 and 2000 and amount to an integrated luminosity of 120 pb{sup -1}. The analysis of 6 different topologies were done and cover all the branching ratios of deexcitation of excited electron and neutrino. The numbers of candidates found during those analysis is in agreement with the Standard Model expectations. This means that no evidence of excited leptons production was found at HERA. This result was translated in the form of exclusion limits on the coupling of excited leptons (f/{lambda}) depending on the mass of the excited lepton. For the first time at HERA we addressed the case were the natural decay width of the excited neutrino is wider than the experimental resolution. For the first time also, a study of the variation of limit depending on the ratio f'/f was carried out. This study lead to the setting of limits independent of this ratio. The limits obtained extend results previously obtained at HEA and also the results of direct searches at LEP. (author)

  18. Search for excited leptons in the data of the H1 experiment at the HERA collider; Recherche de leptons excites dans les donnees de l'experience H1 aupres du collisionneur HERA

    Energy Technology Data Exchange (ETDEWEB)

    Delerue, N

    2002-05-01

    Composite models are one of the possible extensions of the Standard Model. One of their implications, at the energy in the reach of present particles accelerators, would be the excitation of leptons. This PhD. thesis describes the search for excited leptons with the H1 detector installed on the electron-proton collider HERA in Hamburg (Germany). The data used were accumulated between 1994 and 2000 and amount to an integrated luminosity of 120 pb{sup -1}. The analysis of 6 different topologies were done and cover all the branching ratios of deexcitation of excited electron and neutrino. The numbers of candidates found during those analysis is in agreement with the Standard Model expectations. This means that no evidence of excited leptons production was found at HERA. This result was translated in the form of exclusion limits on the coupling of excited leptons (f/{lambda}) depending on the mass of the excited lepton. For the first time at HERA we addressed the case were the natural decay width of the excited neutrino is wider than the experimental resolution. For the first time also, a study of the variation of limit depending on the ratio f'/f was carried out. This study lead to the setting of limits independent of this ratio. The limits obtained extend results previously obtained at HEA and also the results of direct searches at LEP. (author)

  19. An investigation into the radiation damage of the silicon detectors of the H1-PLUG calorimeter within the HERA environment

    International Nuclear Information System (INIS)

    Hildesheim, W.; Seidel, M.

    1995-07-01

    The silicon detectors used in the H1-PLUG calorimeter have shown increasing aging effects during the '94 run period of the electron proton storage ring HERA. These effects were particularly manifest as degradation of the signal to noise level and the calibration stability. The reasons for this behaviour have been found to be correlated with radiation damage to the silicon oxide passivation edges of the detectors in strong and fluctuating increases of the leakage currents and in severe changes of the flat band voltages. Depletion voltages however are found to be stable and therefore bulk damage of the silicon can be excluded. A comparison with measurements made by thermoluminescence dosimeters as well as related laboratory experiments suggest that the aging is due to very low energetic electrons and photons. (orig.)

  20. Measurement of the D± meson cross section in DIS with the H1 detector at HERA

    International Nuclear Information System (INIS)

    Pahl, Philipp

    2014-04-01

    The inclusive production of D ± mesons in deep inelastic scattering at √(s)=318 GeV at HERA is studied using data taken with the Hl detector during the high energy measurement period in the years 2006 and 2007 corresponding to an integrated luminosity of 202.6 pb -1 . The visible phase space is defined by 5 2 2 , 0.05 T (D ± ) and -1.5 ± ) 2 is the photon virtuality, y is the inelasticity and p T (D ± ) and η(D ± ) are the transverse momentum and rapidity of the D ± meson. Charm production events are identified by the reconstruction of the D ± →K -+ π ± π ± decay channel. The sample is enhanced by the application of a multi-variate analysis technique using a multilayer perceptron. The input variables of the classifier are based on the specific energy loss of the kaon decay particle candidate and the reconstructed decay length of the D ± meson. The single and double differential cross sections are compared to leading and next-to-leading order QCD predictions.

  1. Measurement of the proton structure function FL(x,Q2) with the H1 detector at HERA

    International Nuclear Information System (INIS)

    Piec, Sebastian

    2010-12-01

    A measurement of the inclusive cross section for the deep-inelastic scattering of positrons on protons at low four-momentum transfer squared Q 2 is presented. The measurement is used for the extraction of the longitudinal proton structure function F L . The analysis is based on data collected by the H1 experiment during special, low energy runs in the year 2007. The direct technique of the F L determination based on the extraction of the reduced DIS cross sections for three different centre-of-mass energies is used. For the purpose of the analysis a dedicated electron finder has been developed and integrated with the standard H1 reconstruction software H1REC. The algorithm employs information from two independent tracking detectors the Backward Silicon Tracker and the Central Jet Chamber. The performance of the finder is studied. The thesis presents the cross section and the F L measurements in the range of 2.5 GeV 2 ≤Q 2 ≤25 GeV 2 . (orig.)

  2. A study of identified hadron fragmentation on eP collisions at HERA using the H1 detector

    Energy Technology Data Exchange (ETDEWEB)

    Turney, Jonathan Edward

    2002-07-01

    Deep inelastic scattering events from ep collisions, recorded in 1996 and 1997 by the H1 detector at HERA, are used to study the fragmentation properties of identified hadrons in the Breit frame of reference. A review of the theory relevant to this analysis is also presented, together with a description of the H1 detector. Using dE/dx information and neutral secondary particle invariant mass spectra, it is possible to identify samples of {pi}{sup {+-}}, K{sup {+-}}, protons and antiprotons, K{sub S}{sup 0}, and {lambda} hadrons in the Breit frame current hemisphere and measure corresponding exclusive fragmentation functions. The evolution of the fragmentation function peak position and width are studied as a function of hadronic mass and four-momentum transfer, Q. Comparison is made to published results from e{sup +}e{sup -} experiments, models of the hadronic final state, and to predictions from MLLA/LPHD theory. The fragmentation properties of identified hadrons in ep data compare well with those in e{sup +}e{sup -} data, giving further evidence for the universality of quark fragmentation. By applying a MLLA/LPHD calculation using parameters derived from fitting H1 data, it is possible to describe the peak evolution in e{sup +}e{sup -} data as a function of energy, hadronic mass, and the parton shower cut-off parameter, Q{sub 0}{sup h}. However, the MLLA/LPHD calculation is unable to describe the data fully, particularly the e{sup +}e{sup -} -derived width evolution. Furthermore, the Monte Carlo models of the hadronic final state are shown to be incompatible with the detailed parameterisation of MLLA/LPHD, but follow the observed trends in ep data well. (author)

  3. A study of identified hadron fragmentation on eP collisions at HERA using the H1 detector

    International Nuclear Information System (INIS)

    Turney, Jonathan Edward

    2002-01-01

    Deep inelastic scattering events from ep collisions, recorded in 1996 and 1997 by the H1 detector at HERA, are used to study the fragmentation properties of identified hadrons in the Breit frame of reference. A review of the theory relevant to this analysis is also presented, together with a description of the H1 detector. Using dE/dx information and neutral secondary particle invariant mass spectra, it is possible to identify samples of π ± , K ± , protons and antiprotons, K S 0 , and Λ hadrons in the Breit frame current hemisphere and measure corresponding exclusive fragmentation functions. The evolution of the fragmentation function peak position and width are studied as a function of hadronic mass and four-momentum transfer, Q. Comparison is made to published results from e + e - experiments, models of the hadronic final state, and to predictions from MLLA/LPHD theory. The fragmentation properties of identified hadrons in ep data compare well with those in e + e - data, giving further evidence for the universality of quark fragmentation. By applying a MLLA/LPHD calculation using parameters derived from fitting H1 data, it is possible to describe the peak evolution in e + e - data as a function of energy, hadronic mass, and the parton shower cut-off parameter, Q 0 h . However, the MLLA/LPHD calculation is unable to describe the data fully, particularly the e + e - -derived width evolution. Furthermore, the Monte Carlo models of the hadronic final state are shown to be incompatible with the detailed parameterisation of MLLA/LPHD, but follow the observed trends in ep data well. (author)

  4. Measurement of K*±(892) production in deep inelastic ep scattering with the H1 detector at HERA

    International Nuclear Information System (INIS)

    Sunar, Deniz

    2009-07-01

    A first measurement is presented of K * (892) ± vector mesons, observed through the decay chain K * (892) ± → K 0 S π ± → π + π - π ± ; in neutral current deep-inelastic ep scattering. The data were taken at the HERA collider in the years 2005.2007 with centre of mass energy √(s)=319 GeV using the H1 detector and correspond to an integrated luminosity of approximately 302 pb -1 . The measurement of differential cross section was performed in the kinematic range which covers the photon virtuality 5 2 2 and the inelasticity 0:1 *± vector meson is restricted in transverse momentum p T (K *± )>1 GeV and pseudorapidity -1.5 *± )<1.5. The results are compared to predictions of leading order Monte Carlo models matched with the parton showers. Persbericht (orig.)

  5. Measurement of beauty photoproduction near threshold using Di-electron events with the H1 detector at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Aaron, F.D. [National Institute for Physics and Nuclear Engineering (NIPNE), Bucharest (Romania); Bucharest Univ. (Romania). Faculty of Physics; Alexa, C. [National Institute for Physics and Nuclear Engineering (NIPNE), Bucharest (Romania); Andreev, V. [Lebedev Physical Institute, Moscow (RU)] (and others)

    2012-05-15

    The cross section for ep {yields} eb anti bX in photoproduction is measured with the H1 detector at the ep-collider HERA. The decay channel b anti b {yields} eeX' is selected by identifying the semi-electronic decays of the b-quarks. The total production cross section is measured in the kinematic range given by the photon virtuality Q{sup 2} {<=}1 GeV{sup 2}, the inelasticity 0.05{<=} y {<=}0.65 and the pseudorapidity of the b-quarks vertical stroke {eta}(b) vertical stroke, vertical stroke {eta}(anti b) vertical stroke {<=}2. The differential production cross section is measured as a function of the average transverse momentum of the beauty quarks left angle P{sub T}(b) right angle down to the threshold. The results are compared to next-to-leading-order QCD predictions.

  6. Measurement of beauty photoproduction near threshold using di-electron events with the H1 detector at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Aaron, F. D.; Alexa, C.; Andreev, V.; Backovic, S.; Baghdasaryan, A.; Baghdasaryan, S.; Barrelet, E.; Bartel, W.; Begzsuren, K.; Belousov, A.; Belov, P.; Bizot, J. C.; Boudry, V.; Bozovic-Jelisavcic, I.; Bracinik, J.; Brandt, G.; Brinkmann, M.; Brisson, V.; Britzger, D.; Bruncko, D.; Bunyatyan, A.; Bylinkin, A.; Bystritskaya, L.; Campbell, A. J.; Cantun Avila, K. B.; Ceccopieri, F.; Cerny, K.; Cerny, V.; Chekelian, V.; Contreras, J. G.; Coughlan, J. A.; Cvach, J.; Dainton, J. B.; Daum, K.; Delcourt, B.; Delvax, J.; De Wolf, E. A.; Diaconu, C.; Dobre, M.; Dodonov, V.; Dossanov, A.; Dubak, A.; Eckerlin, G.; Egli, S.; Eliseev, A.; Elsen, E.; Favart, L.; Fedotov, A.; Felst, R.; Feltesse, J.; Ferencei, J.; Fischer, D. -J.; Fleischer, M.; Fomenko, A.; Gabathuler, E.; Gayler, J.; Ghazaryan, S.; Glazov, A.; Goerlich, L.; Gogitidze, N.; Gouzevitch, M.; Grab, C.; Grebenyuk, A.; Greenshaw, T.; Grindhammer, G.; Habib, S.; Haidt, D.; Henderson, R. C. W.; Hennekemper, E.; Henschel, H.; Herbst, M.; Herrera, G.; Hildebrandt, M.; Hiller, K. H.; Hoffmann, D.; Horisberger, R.; Hreus, T.; Huber, F.; Jacquet, M.; Janssen, X.; Jönsson, L.; Jung, A. W.; Jung, H.; Kapichine, M.; Kenyon, I. R.; Kiesling, C.; Klein, M.; Kleinwort, C.; Kogler, R.; Kostka, P.; Krämer, M.; Kretzschmar, J.; Krüger, K.; Landon, M. P. J.; Lange, W.; Laštovička-Medin, G.; Laycock, P.; Lebedev, A.; Lendermann, V.; Levonian, S.; Lipka, K.; List, B.; List, J.; Lobodzinski, B.; Lopez-Fernandez, R.; Lubimov, V.; Malinovski, E.; Martyn, H. -U.; Maxfield, S. J.; Mehta, A.; Meyer, A. B.; Meyer, H.; Meyer, J.; Mikocki, S.; Milcewicz-Mika, I.; Moreau, F.; Morozov, A.; Morris, J. V.; Müller, K.; Naumann, Th.; Newman, P. R.; Niebuhr, C.; Nikitin, D.; Nowak, G.; Nowak, K.; Olivier, B.; Olsson, J. E.; Ozerov, D.; Pahl, P.; Palichik, V.; Pandurovic, M.; Pascaud, C.; Patel, G. D.; Perez, E.; Petrukhin, A.; Picuric, I.; Pirumov, H.; Pitzl, D.; Plačakytė, R.; Pokorny, B.; Polifka, R.; Povh, B.; Radescu, V.; Raicevic, N.; Ravdandorj, T.; Reimer, P.; Rizvi, E.; Robmann, P.; Roosen, R.; Rostovtsev, A.; Rotaru, M.; Ruiz Tabasco, J. E.; Rusakov, S.; Šálek, D.; Sankey, D. P. C.; Sauter, M.; Sauvan, E.; Schmitt, S.; Schoeffel, L.; Schöning, A.; Schultz-Coulon, H. -C.; Sefkow, F.; Shtarkov, L. N.; Shushkevich, S.; Sloan, T.; Soloviev, Y.; Sopicki, P.; South, D.; Spaskov, V.; Specka, A.; Staykova, Z.; Steder, M.; Stella, B.; Stoicea, G.; Straumann, U.; Sykora, T.; Thompson, P. D.; Tran, T. H.; Traynor, D.; Truöl, P.; Tsakov, I.; Tseepeldorj, B.; Turnau, J.; Valkárová, A.; Vallée, C.; Van Mechelen, P.; Vazdik, Y.; Wegener, D.; Wünsch, E.; Žáček, J.; Zálešák, J.; Zhang, Z.; Zhokin, A.; Žlebčík, R.; Zohrabyan, H.; Zomer, F.

    2012-10-01

    The cross section for $ep \\to e b\\bar{b} X$ in photoproduction is measured with the H1 detector at the $ep$-collider HERA. The decay channel $b\\bar{b} \\to ee X^\\prime$ is selected by identifying the semi-electronic decays of the b-quarks. The total production cross section is measured in the kinematic range given by the photon virtuality $Q^2 \\le 1 GeV^2$, the inelasticity $0.05 \\le y \\le 0.65$ and the pseudorapidity of the $b$-quarks $|\\eta(b)|$,$|\\eta(\\bar{b})| \\le 2$. The differential production cross section is measured as a function of the average transverse momentum of the beauty quarks <$P_T$(b)> down to the threshold. The results are compared to next-to-leading-order QCD predictions.

  7. Measurement of beauty photoproduction near threshold using Di-electron events with the H1 detector at HERA

    International Nuclear Information System (INIS)

    Aaron, F.D.; Andreev, V.

    2012-05-01

    The cross section for ep → eb anti bX in photoproduction is measured with the H1 detector at the ep-collider HERA. The decay channel b anti b → eeX' is selected by identifying the semi-electronic decays of the b-quarks. The total production cross section is measured in the kinematic range given by the photon virtuality Q 2 ≤1 GeV 2 , the inelasticity 0.05≤ y ≤0.65 and the pseudorapidity of the b-quarks vertical stroke η(b) vertical stroke, vertical stroke η(anti b) vertical stroke ≤2. The differential production cross section is measured as a function of the average transverse momentum of the beauty quarks left angle P T (b) right angle down to the threshold. The results are compared to next-to-leading-order QCD predictions.

  8. D*± meson production at low Q2 with the H1 detector and determination of unintegrated gluon densities

    International Nuclear Information System (INIS)

    Cholewa, Axel

    2011-02-01

    A study of inclusive D *± meson production in deep inelastic electron-proton scattering at the H1 detector is presented for low photon virtualities. The results of these measurements have been used to determine unintegrated gluon densities with the Monte Carlo generator CASCADE. The phase space of the measurement is defined by photon virtualities inside 2 GeV 2 2 2 , and inelasticities inside 0.02 *± mesons is restricted to pseudo rapidities of vertical stroke η D * vertical stroke t D * >1.5 GeV and complements D *± meson production measurements at higher photon virtualities. Data taken in the years 2004-2007 during the HERA II running period have been analyzed yielding an integrated luminosity of 348 pb -1 . This significant increase in statistics compared to HERA I was exploited in the single and double differential cross sections which have been measured more differentiated than in previous measurements at H1. The single differential cross sections have been used in parameter fits of unintegrated gluon densities. For this purpose scattering events in electron-proton collisions were simulated with the Monte Carlo generator CASCADE and the deviation of the prediction of the simulation from the measured data was then minimized with the χ 2 method. Three different parametrizations of unintegrated gluon distributions have been used and compared. (orig.)

  9. Elastic and proton dissociative J/ψ photoproduction at low Wγp with the H1 detector at HERA

    International Nuclear Information System (INIS)

    Huber, Florian

    2013-02-01

    Elastic and proton dissociative photoproduction of J/ψ mesons is measured with the H1 detector at the HERA electron proton collider in the photon virtuality phase space of Q 2 2 . Two data sets are analysed, one measured with a nominal proton beam energy of 920 GeV, corresponding to an ep centre of mass energy of 318 GeV and one recorded with a reduced beam energy of 460 GeV, corresponding to an ep centre of mass energy of 225 GeV. The combination of the two data sets allow to perform the J/ψ measurement with central tracks in an extended kinematic phase space in a photon proton centre of mass energy range of 20 GeV γp -1 and 10.8 pb -1 , respectively, corresponding to more than two times the statistics used in previous H1 analyses. Due to an online selection purely based on tracks both leptonic decay channels J/ψ→ee and J/ψ→μμ are available for the analysis. Elastic (γp→ J/ψp) and proton dissociative (γp→ J/ψY) differential γp cross sections are determined in a simultaneous measurement as function of the squared momentum transfer at the proton vertex t and as function of W γp by means of an unfolding procedure, taking not only all bin correlations into account, but also the correlation between the elastic and proton dissociative process. The obtained elastic and proton dissociative differential cross sections are analysed in a simultaneous fit, taking the full statistical covariance matrices and systematic uncertainty sources into account.

  10. Measurement of K{sup *{+-}}(892) production in deep inelastic ep scattering with the H1 detector at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Sunar, Deniz

    2009-07-15

    A first measurement is presented of K{sup *}(892){sup {+-}} vector mesons, observed through the decay chain K{sup *}(892){sup {+-}} {yields} K{sup 0}{sub S}{pi}{sup {+-}} {yields} {pi}{sup +}{pi}{sup -}{pi}{sup {+-}}; in neutral current deep-inelastic ep scattering. The data were taken at the HERA collider in the years 2005.2007 with centre of mass energy {radical}(s)=319 GeV using the H1 detector and correspond to an integrated luminosity of approximately 302 pb{sup -1}. The measurement of differential cross section was performed in the kinematic range which covers the photon virtuality 51 GeV and pseudorapidity -1.5<{eta}(K{sup *{+-}})<1.5. The results are compared to predictions of leading order Monte Carlo models matched with the parton showers. Persbericht (orig.)

  11. Measurement of beauty photoproduction at threshold using di-electron events with the H1 detector at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Sauter, Michel David

    2009-12-15

    The cross section of b anti b photoproduction in ep collisions has been measured with the H1 detector at HERA. Events containing b-quarks were identified through detection of two low momentum electrons in the nal state. Semileptonic decays b anti b{yields}eeX were exploited in the kinematic range of the photon virtuality Q{sup 2}<1 GeV{sup 2}, the inelasticity 0.2

  12. Measurement of charm and beauty dijet cross sections in photoproduction at HERA using the H1 vertex detector

    Science.gov (United States)

    Aktas, A.; Andreev, V.; Anthonis, T.; Antunovic, B.; Aplin, S.; Asmone, A.; Astvatsatourov, A.; Babaev, A.; Backovic, S.; Baghdasaryan, A.; Baranov, P.; Barrelet, E.; Bartel, W.; Baudrand, S.; Baumgartner, S.; Becker, J.; Beckingham, M.; Behnke, O.; Behrendt, O.; Belousov, A.; Berger, N.; Bizot, J. C.; Boenig, M.-O.; Boudry, V.; Bracinik, J.; Brandt, G.; Brisson, V.; Bruncko, D.; Büsser, F. W.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A. J.; Cassol-Brunner, F.; Cerny, K.; Cerny, V.; Chekelian, V.; Contreras, J. G.; Coughlan, J. A.; Cox, B. E.; Cozzika, G.; Cvach, J.; Dainton, J. B.; Dau, W. D.; Daum, K.; de Boer, Y.; Delcourt, B.; Del Degan, M.; de Roeck, A.; de Wolf, E. A.; Diaconu, C.; Dodonov, V.; Dubak, A.; Eckerlin, G.; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Eliseev, A.; Elsen, E.; Essenov, S.; Falkewicz, A.; Faulkner, P. J. W.; Favart, L.; Fedotov, A.; Felst, R.; Feltesse, J.; Ferencei, J.; Finke, L.; Fleischer, M.; Flucke, G.; Fomenko, A.; Franke, G.; Frisson, T.; Gabathuler, E.; Garutti, E.; Gayler, J.; Gerlich, C.; Ghazaryan, S.; Ginzburgskaya, S.; Glazov, A.; Glushkov, I.; Goerlich, L.; Goettlich, M.; Gogitidze, N.; Gorbounov, S.; Grab, C.; Greenshaw, T.; Gregori, M.; Grell, B. R.; Grindhammer, G.; Gwilliam, C.; Haidt, D.; Hajduk, L.; Hansson, M.; Heinzelmann, G.; Henderson, R. C. W.; Henschel, H.; Herrera, G.; Hildebrandt, M.; Hiller, K. H.; Hoffmann, D.; Horisberger, R.; Hovhannisyan, A.; Hreus, T.; Hussain, S.; Ibbotson, M.; Ismail, M.; Jacquet, M.; Janauschek, L.; Janssen, X.; Jemanov, V.; Jönsson, L.; Johnson, D. P.; Jung, A. W.; Jung, H.; Kapichine, M.; Katzy, J.; Kenyon, I. R.; Kiesling, C.; Klein, M.; Kleinwort, C.; Klimkovich, T.; Kluge, T.; Knies, G.; Knutsson, A.; Korbel, V.; Kostka, P.; Krastev, K.; Kretzschmar, J.; Kropivnitskaya, A.; Krüger, K.; Landon, M. P. J.; Lange, W.; Laštovička-Medin, G.; Laycock, P.; Lebedev, A.; Leibenguth, G.; Lendermann, V.; Levonian, S.; Lindfeld, L.; Lipka, K.; Liptaj, A.; List, B.; List, J.; Lobodzinska, E.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Lucaci-Timoce, A.-I.; Lueders, H.; Lüke, D.; Lux, T.; Lytkin, L.; Makankine, A.; Malden, N.; Malinovski, E.; Mangano, S.; Marage, P.; Marshall, R.; Marti, L.; Martisikova, M.; Martyn, H.-U.; Maxfield, S. J.; Mehta, A.; Meier, K.; Meyer, A. B.; Meyer, H.; Meyer, J.; Michels, V.; Mikocki, S.; Milcewicz-Mika, I.; Milstead, D.; Mladenov, D.; Mohamed, A.; Moreau, F.; Morozov, A.; Morris, J. V.; Mozer, M. U.; Müller, K.; Murín, P.; Nankov, K.; Naroska, B.; Naumann, Th.; Newman, P. R.; Niebuhr, C.; Nikiforov, A.; Nowak, G.; Nowak, K.; Nozicka, M.; Oganezov, R.; Olivier, B.; Olsson, J. E.; Osman, S.; Ozerov, D.; Palichik, V.; Panagoulias, I.; Papadopoulou, T.; Pascaud, C.; Patel, G. D.; Peng, H.; Perez, E.; Perez-Astudillo, D.; Perieanu, A.; Petrukhin, A.; Pitzl, D.; Plačakytė, R.; Portheault, B.; Povh, B.; Prideaux, P.; Rahmat, A. J.; Raicevic, N.; Reimer, P.; Rimmer, A.; Risler, C.; Rizvi, E.; Robmann, P.; Roland, B.; Roosen, R.; Rostovtsev, A.; Rurikova, Z.; Rusakov, S.; Salvaire, F.; Sankey, D. P. C.; Sauvan, E.; Schätzel, S.; Schmidt, S.; Schmitt, S.; Schmitz, C.; Schoeffel, L.; Schöning, A.; Schultz-Coulon, H.-C.; Sefkow, F.; Shaw-West, R. N.; Sheviakov, I.; Shtarkov, L. N.; Sloan, T.; Smirnov, P.; Soloviev, Y.; South, D.; Spaskov, V.; Specka, A.; Steder, M.; Stella, B.; Stiewe, J.; Stoilov, A.; Straumann, U.; Sunar, D.; Tchoulakov, V.; Thompson, G.; Thompson, P. D.; Toll, T.; Tomasz, F.; Traynor, D.; Truöl, P.; Tsakov, I.; Tsipolitis, G.; Tsurin, I.; Turnau, J.; Tzamariudaki, E.; Urban, K.; Urban, M.; Usik, A.; Utkin, D.; Valkárová, A.; Vallée, C.; van Mechelen, P.; Vargas Trevino, A.; Vazdik, Y.; Veelken, C.; Vinokurova, S.; Volchinski, V.; Wacker, K.; Weber, G.; Weber, R.; Wegener, D.; Werner, C.; Wessels, M.; Wessling, B.; Wissing, Ch.; Wolf, R.; Wünsch, E.; Xella, S.; Yan, W.; Yeganov, V.; Žáček, J.; Zálešák, J.; Zhang, Z.; Zhelezov, A.; Zhokin, A.; Zhu, Y. C.; Zimmermann, J.; Zimmermann, T.; Zohrabyan, H.; Zomer, F.

    2006-09-01

    A measurement of charm and beauty dijet photoproduction cross sections at the ep collider HERA is presented. Events are selected with two or more jets of transverse momentum pt jet1(2)>11(8) GeV in the central range of pseudo-rapidity -0.9<ηjet1(2)<1.3. The fractions of events containing charm and beauty quarks are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured by the H1 central vertex detector. Differential dijet cross sections for charm and beauty, and their relative contributions to the flavour inclusive dijet photoproduction cross section, are measured as a function of the transverse momentum of the leading jet, the average pseudo-rapidity of the two jets and the observable xγ obs. Taking into account the theoretical uncertainties, the charm cross sections are consistent with a QCD calculation in next-to-leading order, while the predicted cross sections for beauty production are somewhat lower than the measurement.

  13. Measurement of Charm and Beauty Dijet Cross Sections in Photoproduction at HERA using the H1 Vertex Detector

    CERN Document Server

    Aktas, A.; Anthonis, T.; Antunovic, B.; Aplin, S.; Asmone, A.; Astvatsatourov, A.; Babaev, A.; Backovic, S.; Baghdasaryan, A.; Baranov, P.; Barrelet, E.; Bartel, W.; Baudrand, S.; Baumgartner, S.; Becker, J.; Beckingham, M.; Behnke, O.; Behrendt, O.; Belousov, A.; Berger, N.; Bizot, J.C.; Boenig, M.-O.; Boudry, V.; Bracinik, J.; Brandt, G.; Brisson, V.; Bruncko, D.; Busser, F.W.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A.J.; Cassol-Brunner, F.; Cerny, K.; Cerny, V.; Chekelian, V.; Contreras, J.G.; Coughlan, J.A.; Cox, B.E.; Cozzika, G.; Cvach, J.; Dainton, J.B.; Dau, W.D.; Daum, K.; de Boer, Y.; Delcourt, B.; Del Degan, M.; De Roeck, A.; De Wolf, E.A.; Diaconu, C.; Dodonov, V.; Dubak, A.; Eckerlin, Guenter; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Eliseev, A.; Elsen, E.; Essenov, S.; Falkewicz, A.; Faulkner, P.J.W.; Favart, L.; Fedotov, A.; Felst, R.; Feltesse, J.; Ferencei, J.; Finke, L.; Fleischer, M.; Flucke, G.; Fomenko, A.; Franke, G.; Frisson, T.; Gabathuler, E.; Garutti, E.; Gayler, J.; Gerlich, C.; Ghazaryan, Samvel; Ginzburgskaya, S.; Glazov, A.; Glushkov, I.; Goerlich, L.; Goettlich, M.; Gogitidze, N.; Gorbounov, S.; Grab, C.; Greenshaw, T.; Gregori, M.; Grell, B.R.; Grindhammer, G.; Gwilliam, C.; Haidt, D.; Hajduk, L.; Hansson, M.; Heinzelmann, G.; Henderson, R.C.W.; Henschel, H.; Herrera, G.; Hildebrandt, M.; Hiller, K.H.; Hoffmann, D.; Horisberger, R.; Hovhannisyan, A.; Hreus, T.; Hussain, S.; Ibbotson, M.; Ismail, M.; Jacquet, M.; Janauschek, L.; Janssen, X.; Jemanov, V.; Jonsson, L.; Johnson, D.P.; Jung, Andreas Werner; Jung, H.; Kapichine, M.; Katzy, J.; Kenyon, I.R.; Kiesling, Christian M.; Klein, M.; Kleinwort, C.; Klimkovich, T.; Kluge, T.; Knies, G.; Knutsson, A.; Korbel, V.; Kostka, P.; Krastev, K.; Kretzschmar, J.; Kropivnitskaya, A.; Kruger, K.; Landon, M.P.J.; Lange, W.; Lastovicka-Medin, G.; Laycock, P.; Lebedev, A.; Leibenguth, G.; Lendermann, V.; Levonian, S.; Lindfeld, L.; Lipka, K.; Liptaj, A.; List, B.; List, J.; Lobodzinska, E.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Lucaci-Timoce, A.-I.; Lueders, H.; Luke, D.; Lux, T.; Lytkin, L.; Makankine, A.; Malden, N.; Malinovski, E.; Mangano, S.; Marage, P.; Marshall, R.; Marti, L.; Martisikova, M.; Martyn, H.-U.; Maxfield, S.J.; Mehta, A.; Meier, K.; Meyer, A.B.; Meyer, H.; Meyer, J.; Michels, V.; Mikocki, S.; Milcewicz-Mika, I.; Milstead, D.; Mladenov, D.; Mohamed, A.; Moreau, F.; Morozov, A.; Morris, J.V.; Mozer, Matthias Ulrich; Muller, K.; Murin, P.; Nankov, K.; Naroska, B.; Naumann, Th.; Newman, Paul R.; Niebuhr, C.; Nikiforov, A.; Nowak, G.; Nowak, K.; Nozicka, M.; Oganezov, R.; Olivier, B.; Olsson, J.E.; Osman, S.; Ozerov, D.; Palichik, V.; Panagoulias, I.; Papadopoulou, T.; Pascaud, C.; Patel, G.D.; Peng, H.; Perez, E.; Perez-Astudillo, D.; Perieanu, A.; Petrukhin, A.; Pitzl, D.; Placakyte, R.; Portheault, B.; Povh, B.; Prideaux, P.; Rahmat, A.J.; Raicevic, N.; Reimer, P.; Rimmer, A.; Risler, C.; Rizvi, E.; Robmann, P.; Roland, B.; Roosen, R.; Rostovtsev, A.; Rurikova, Z.; Rusakov, S.; Salvaire, F.; Sankey, D.P.C.; Sauvan, E.; Schatzel, S.; Schmidt, S.; Schmitt, S.; Schmitz, C.; Schoeffel, L.; Schoning, A.; Schultz-Coulon, H.-C.; Sefkow, F.; Shaw-West, R.N.; Sheviakov, I.; Shtarkov, L.N.; Sloan, T.; Smirnov, P.; Soloviev, Y.; South, D.; Spaskov, V.; Specka, Arnd E.; Steder, M.; Stella, B.; Stiewe, J.; Stoilov, A.; Straumann, U.; Sunar, D.; Tchoulakov, V.; Thompson, G.; Thompson, P.D.; Toll, T.; Tomasz, F.; Traynor, D.; Truol, P.; Tsakov, I.; Tsipolitis, G.; Tsurin, I.; Turnau, J.; Tzamariudaki, E.; Urban, K.; Urban, Marcel; Usik, A.; Utkin, D.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Vargas Trevino, A.; Vazdik, Y.; Veelken, C.; Vinokurova, S.; Volchinski, V.; Wacker, K.; Weber, G.; Weber, R.; Wegener, D.; Werner, C.; Wessels, M.; Wessling, B.; Wissing, Ch.; Wolf, R.; Wunsch, E.; Xella, S.; Yan, W.; Yeganov, V.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhelezov, A.; Zhokin, A.; Zhu, Y.C.; Zimmermann, J.; Zimmermann, T.; Zohrabyan, H.; Zomer, F.

    2006-01-01

    A measurement of charm and beauty dijet photoproduction cross sections at the ep collider HERA is presented. Events are selected with two or more jets of transverse momentum $p_t^{jet}_{1(2)}>11(8)$ GeV in the central range of pseudo-rapidity $-0.9<\\eta^{jet}_{1(2)}<1.3$. The fractions of events containing charm and beauty quarks are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured by the H1 central vertex detector. Differential dijet cross sections for charm and beauty, and their relative contributions to the flavour inclusive dijet photoproduction cross section, are measured as a function of the transverse momentum of the leading jet, the average pseudo-rapidity of the two jets and the observable $x_{\\gamma}^{obs}$. Taking into account the theoretical uncertainties, the charm cross sections are consistent with a QCD calculation in next-to-leading order, while the predicted cross sections for beauty production are somewhat lo...

  14. Measurement of D{sup *} meson with two jets in photoproduction with the H1 detector at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Staykova, Zlatka

    2011-02-15

    Photoproduction events containing a charmed meson D{sup *{+-}} and two jets are investigated with the H1 detector using the HERA II data sample. The measurement is based on e{sup +}p collisions during the period of 2006/2007 data taking and uses integrated luminosity of 113.14 pb{sup -1}. The kinematic range of the measurement covers 100 GeV3.5 GeV. One of the jets has to be associated with the D{sup *} meson itself, such that the parent charmed quark can be tagged. The phase space of the measurement is limited within the central rapidity for the D{sup *} meson and the D{sup *}{sub jet}, vertical stroke {eta} vertical stroke <1.5 while the second jet was measured within, -1.5<{eta}<2.9. Single differential cross sections and double differential distributions were measured and compared to Leading Order Monte Carlo (MC) event generators, Pythia and Cascade and with the Next-to-Leading order MC generator MC rate at NLO. (orig.)

  15. H1 at HERA Exhibition

    CERN Multimedia

    2000-01-01

    H1 is one of the two large detectors installed at HERA, the first electron-proton accelerator, located at DESY in Hamburg. The H1 collaboration regroups physicists from 32institutes of 11countries all over the world.

  16. Measurement of the proton structure function F{sub L}(x,Q{sup 2}) with the H1 detector at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Piec, Sebastian

    2010-12-15

    A measurement of the inclusive cross section for the deep-inelastic scattering of positrons on protons at low four-momentum transfer squared Q{sup 2} is presented. The measurement is used for the extraction of the longitudinal proton structure function F{sub L}. The analysis is based on data collected by the H1 experiment during special, low energy runs in the year 2007. The direct technique of the F{sub L} determination based on the extraction of the reduced DIS cross sections for three different centre-of-mass energies is used. For the purpose of the analysis a dedicated electron finder has been developed and integrated with the standard H1 reconstruction software H1REC. The algorithm employs information from two independent tracking detectors the Backward Silicon Tracker and the Central Jet Chamber. The performance of the finder is studied. The thesis presents the cross section and the F{sub L} measurements in the range of 2.5 GeV{sup 2}{<=}Q{sup 2}{<=}25 GeV{sup 2}. (orig.)

  17. Measurement of the structure function F2 of the proton in deep inelastic e-p scattering with the H1 detector at the HERA storage ring

    International Nuclear Information System (INIS)

    Wellisch, J.P.

    1994-02-01

    This thesis presents the measurement of the structure function F 2 of the proton with the H1 detector at 10 GeV 2 2 2 and 10 -4 -2 . The analysis contains the data of the first year of the HERA operation. The applied integrated luminosity amounts to 22.5 nb -1 . Contrarily to earlier experiments of the deep inelastic scattering it is at H1 possible to apply also the hadronic final state for the reconstruction of the event kinematics. In this thesis ten methods for the reconstruction of the event kinematics are indicated and studied in the region Q 2 2 in detailed detector simulation on resolution, systematic effects, measurable kinematical range and sensitivity to radiation of photons from the electron. For H1 as most advantageous methods for the reconstruction of the event kinematics on the one hand the exclusive application of the electron information and on the other hand the combination of the measurement of the momentum transfer from energy and direction of the scattered electron with the measurement of the relative energy transfer y from the scattering of electron and quark have been proved. Thereby a new, for the range of small momentum transfers especially suited method, for the reconstruction of the scattering angle of the quark was indicated. A significant increasement of the structure function F 2 of the proton at small x. At large x the continuation to the results found in earlier measurements is continuous. At fixed x the structure function increases slowly in agreement with the predictions of QCD with increasing momentum transfer

  18. Measurement of F_2^ccbar and F_2^bbbar at High Q^2 using the H1 Vertex Detector at HERA

    CERN Document Server

    Aktas, A.; Anthonis, T.; Aplin, S.; Asmone, A.; Babaev, A.; Backovic, S.; Bahr, J.; Baghdasaryan, A.; Baranov, P.; Barrelet, E.; Bartel, W.; Baudrand, S.; Baumgartner, S.; Becker, J.; Beckingham, M.; Behnke, O.; Behrendt, O.; Belousov, A.; Berger, Ch.; Berger, N.; Berndt, T.; Bizot, J.C.; Bohme, J.; Boenig, M.-O.; Boudry, V.; Bracinik, J.; Brandt, G.; Brisson, V.; Broker, H.-B.; Brown, D.P.; Bruncko, D.; Busser, F.W.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A.J.; Caron, S.; Cassol-Brunner, F.; Cerny, K.; Chekelian, V.; Contreras, J.G.; Coppens, Y.R.; Coughlan, J.A.; Cox, B.E.; Cozzika, G.; Cvach, J.; Dainton, J.B.; Dau, W.D.; Daum, K.; Delcourt, B.; Demirchyan, R.; De Roeck, A.; Desch, K.; De Wolf, E.A.; Diaconu, C.; Dingfelder, J.; Dodonov, V.; Dubak, A.; Duprel, C.; Eckerlin, Guenter; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Ellerbrock, M.; Elsen, E.; Erdmann, W.; Essenov, S.; Faulkner, P.J.W.; Favart, L.; Fedotov, A.; Felst, R.; Ferencei, J.; Finke, L.; Fleischer, M.; Fleischmann, P.; Fleming, Y.H.; Flucke, G.; Flugge, G.; Fomenko, A.; Foresti, I.; Formanek, J.; Franke, G.; Frising, G.; Frisson, T.; Gabathuler, E.; Gabathuler, K.; Garutti, E.; Garvey, J.; Gayler, J.; Gerhards, R.; Gerlich, C.; Ghazaryan, Samvel; Ginzburgskaya, S.; Glazov, A.; Glushkov, I.; Goerlich, L.; Goettlich, M.; Gogitidze, N.; Gorbounov, S.; Goyon, C.; Grab, C.; Grassler, H.; Greenshaw, T.; Gregori, M.; Grindhammer, Guenter; Gwilliam, C.; Haidt, D.; Hajduk, L.; Haller, J.; Hansson, M.; Heinzelmann, G.; Henderson, R.C.W.; Henschel, H.; Henshaw, O.; Herrera, G.; Herynek, I.; Heuer, R.-D.; Hildebrandt, M.; Hiller, K.H.; Hoting, P.; Hoffmann, D.; Horisberger, R.; Hovhannisyan, A.; Ibbotson, M.; Ismail, M.; Jacquet, M.; Janauschek, L.; Janssen, X.; Jemanov, V.; Jonsson, L.; Johnson, D.P.; Jung, H.; Kant, D.; Kapichine, M.; Karlsson, M.; Katzy, J.; Keller, N.; Kenyon, I.R.; Kiesling, Christian M.; Klein, M.; Kleinwort, C.; Klimkovich, T.; Kluge, T.; Knies, G.; Knutsson, A.; Korbel, V.; Kostka, P.; Koutouev, R.; Kropivnitskaya, A.; Kruger, K.; Kuckens, J.; Landon, M.P.J.; Lange, W.; Lastovicka, T.; Laycock, P.; Lebedev, A.; Leiner, B.; Lemrani, R.; Lendermann, V.; Levonian, S.; Lindfeld, L.; Lipka, K.; List, B.; Lobodzinska, E.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Lueders, H.; Luke, D.; Lux, T.; Lytkin, L.; Makankine, A.; Malden, N.; Malinovski, E.; Mangano, S.; Marage, P.; Marks, J.; Marshall, R.; Martisikova, M.; Martyn, H.-U.; Maxeld, S.J.; Meer, D.; Mehta, A.; Meier, K.; Meyer, A.B.; Meyer, H.; Meyer, J.; Mikocki, S.; Milcewicz-Mika, I.; Milstead, D.; Mohamed, A.; Moreau, F.; Morozov, A.; Morris, J.V.; Mozer, Matthias Ulrich; Muller, K.; Murin, P.; Nagovizin, V.; Nankov, K.; Naroska, B.; Naumann, J.; Naumann, Th.; Newman, Paul R.; Niebuhr, C.; Nikiforov, A.; Nikitin, D.; Nowak, G.; Nozicka, M.; Oganezov, R.; Olivier, B.; Olsson, J.E.; Ozerov, D.; Pascaud, C.; Patel, G.D.; Peez, M.; Perez, E.; Perez-Astudillo, D.; Perieanu, A.; Petrukhin, A.; Pitzl, D.; Placakyte, R.; Poschl, R.; Portheault, B.; Povh, B.; Prideaux, P.; Raicevic, N.; Reimer, P.; Rimmer, A.; Risler, C.; Rizvi, E.; Robmann, P.; Roland, B.; Roosen, R.; Rostovtsev, A.; Rurikova, Z.; Rusakov, S.; Salvaire, F.; Sankey, D.P.C.; Sauvan, E.; Schatzel, S.; Scheins, J.; Schilling, F.-P.; Schmidt, S.; Schmitt, S.; Schmitz, C.; Schneider, M.; Schoeffel, L.; Schoning, A.; Schroder, V.; Schultz-Coulon, H.-C.; Schwanenberger, C.; Sedlak, K.; Sefkow, F.; Sheviakov, I.; Shtarkov, L.N.; Sirois, Y.; Sloan, T.; Smirnov, P.; Soloviev, Y.; South, D.; Spaskov, V.; Specka, Arnd E.; Stella, B.; Stiewe, J.; Strauch, I.; Straumann, U.; Tchoulakov, V.; Thompson, Graham; Thompson, P.D.; Tomasz, F.; Traynor, D.; Truoel, Peter; Tsipolitis, G.; Tsurin, I.; Turnau, J.; Tzamariudaki, E.; Uraev, A.; Urban, Marcel; Usik, A.; Utkin, D.; Valkar, S.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Van Remortel, N.; Vargas Trevino, A.; Vazdik, Y.; Veelken, C.; Vest, A.; Vinokurova, S.; Volchinski, V.; Vujicic, B.; Wacker, K.; Wagner, J.; Weber, G.; Weber, R.; Wegener, D.; Werner, C.; Werner, N.; Wessels, M.; Wessling, B.; Wigmore, C.; Winter, G.-G.; Wissing, Ch.; Woehrling, E.-E.; Wolf, R.; Wunsch, E.; Xella, S.; Yan, W.; Yeganov, V.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhelezov, A.; Zhokin, A.; Zimmermann, J.; Zohrabyan, H.; Zomer, F.

    2004-01-01

    Measurements are presented of inclusive charm and beauty cross sections in e^+p collisions at HERA for values of photon virtuality Q^2 > 150 GeV^2 and of inelasticity 0.1 < y < 0.7. The charm and beauty fractions are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured by the H1 vertex detector. The data are divided into four regions in Q^2 and Bjorken x, and values for the structure functions F_2^{c\\bar{c}} and F_2^{b\\bar{b}} are obtained. The results are found to be compatible with the predictions of perturbative quantum chromodynamics.

  19. Elastic and proton dissociative J/{psi} photoproduction at low W{sub {gamma}p} with the H1 detector at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Huber, Florian

    2013-02-15

    Elastic and proton dissociative photoproduction of J/{psi} mesons is measured with the H1 detector at the HERA electron proton collider in the photon virtuality phase space of Q{sup 2}H1 analyses. Due to an online selection purely based on tracks both leptonic decay channels J/{psi}{yields}ee and J/{psi}{yields}{mu}{mu} are available for the analysis. Elastic ({gamma}p{yields} J/{psi}p) and proton dissociative ({gamma}p{yields} J/{psi}Y) differential {gamma}p cross sections are determined in a simultaneous measurement as function of the squared momentum transfer at the proton vertex t and as function of W{sub {gamma}p} by means of an unfolding procedure, taking not only all bin correlations into account, but also the correlation between the elastic and proton dissociative process. The obtained elastic and proton dissociative differential cross sections are analysed in a simultaneous fit, taking the full statistical covariance matrices and systematic uncertainty sources into account.

  20. Simulation and calibration of the specific energy loss of the central jet chambers of the H1 detector and measurement of the inclusive D*± meson cross section in photoproduction at HERA

    International Nuclear Information System (INIS)

    Hennekemper, Eva

    2011-12-01

    In this thesis the photoproduction of D * mesons in ep collisions at HERA is analysed. D * mesons are detected in the 'golden' decay channel D * → Kππ s with the H1 detector. Compared to earlier analyses, the systematic uncertainty is reduced due to two main improvements. Firstly, the simulation of the Fast Track Trigger, which is based on tracks measured within the central jet chambers, allows the trigger efficiency dependence of various kinematic variables to be evaluated. Secondly, the use of specific energy loss provides the possibility to suppress the non-resonant background. In order to use particle identification with the specific energy loss in the analysis, the simulation of the specific energy loss in the central jet chambers of the H1 detector is improved and the necessary correction functions and calibrations have been determined. This improved final H1 detector simulation is used to determine the cross section of photoproduction of D * mesons in the HERA II data sample, which corresponds to an integrated luminosity of 113 pb -1 . The measurement was performed in the kinematic region of Q 2 γp * mesons with transverse momenta above 1.8 GeV and in the central pseudorapidity range of vertical stroke η(D * ) vertical stroke <1.5 are determined and are compared to leading and next to leading order QCD predictions. (orig.)

  1. Measurement of the D*± meson cross section and extraction of the charm contribution, Fc2(x, Q2), to the proton structure in deep inelastic ep scattering with the H1 detector at HERA

    International Nuclear Information System (INIS)

    Jung, Andreas Werner

    2009-01-01

    Inclusive production of D * mesons in deep inelastic scattering at HERA is studied using data taken with the H1 detector in the years 2004 to 2007 corresponding to an integrated luminosity of 347 pb -1 . The measurement covers the region 5 2 2 in photon virtuality and the increased region 0.02 * meson is restricted in transverse momentum and pseudorapidity to p T (D * )>1.5 GeV and vertical stroke η(D * ) vertical stroke c 2 (x,Q 2 ), to the proton structure in different QCD evolution schemes is derived from the D * cross sections and compared to next-to-leading order perturbative QCD predictions. This F c 2 measurement is performed using a factor of 18 more data compared to the previous H1 publication. The present thesis additionally describes a successfully completed hardware project: The commissioning and optimisation of the third level of the H1 Fast Track Trigger (FTT), which was fully operational from 2006 onwards. The FTT is integrated in the first three levels of the H1 trigger system and provides enhanced selectivity for events with charged particles. The third trigger level of the FTT performs a track-based event reconstruction within a latency of about 100 μs. The third trigger level of the FTT is realised by a farm of PowerPC boards. Furthermore, the FTT simulation is now incorporated into the H1 trigger simulation. (orig.)

  2. Measurement of the D*± meson production cross section at low and medium Q2 with the H1 detector at HERA

    International Nuclear Information System (INIS)

    Dobre, Monica

    2012-11-01

    The inclusive production of D ± (2010) mesons in deep inelastic scattering is studied using data recorded by the H1 experiment in the years 1999 to 2000 and corresponding to an integrated luminosity of 47.66 pb -1 . The measurement covers the region 2 2 2 in photon virtuality and the region 0.02 *± meson production is restricted in transverse momentum to p T (D * )>1.25 GeV and in pseudorapidity to vertical stroke η(D * ) vertical stroke <1.8. Single and double differential cross sections are compared to leading order and next-to-leading order perturbative QCD predictions.

  3. Measurement of the D{sup *{+-}} meson production cross section at low and medium Q{sup 2} with the H1 detector at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Dobre, Monica

    2012-11-15

    The inclusive production of D{sup {+-}}(2010) mesons in deep inelastic scattering is studied using data recorded by the H1 experiment in the years 1999 to 2000 and corresponding to an integrated luminosity of 47.66 pb{sup -1}. The measurement covers the region 21.25 GeV and in pseudorapidity to vertical stroke {eta}(D{sup *}) vertical stroke <1.8. Single and double differential cross sections are compared to leading order and next-to-leading order perturbative QCD predictions.

  4. Simulation and calibration of the specific energy loss of the central jet chambers of the H1 detector and measurement of the inclusive D{sup *{+-}} meson cross section in photoproduction at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Hennekemper, Eva

    2011-12-15

    In this thesis the photoproduction of D{sup *} mesons in ep collisions at HERA is analysed. D{sup *} mesons are detected in the 'golden' decay channel D{sup *} {yields} K{pi}{pi}{sub s} with the H1 detector. Compared to earlier analyses, the systematic uncertainty is reduced due to two main improvements. Firstly, the simulation of the Fast Track Trigger, which is based on tracks measured within the central jet chambers, allows the trigger efficiency dependence of various kinematic variables to be evaluated. Secondly, the use of specific energy loss provides the possibility to suppress the non-resonant background. In order to use particle identification with the specific energy loss in the analysis, the simulation of the specific energy loss in the central jet chambers of the H1 detector is improved and the necessary correction functions and calibrations have been determined. This improved final H1 detector simulation is used to determine the cross section of photoproduction of D{sup *} mesons in the HERA II data sample, which corresponds to an integrated luminosity of 113 pb{sup -1}. The measurement was performed in the kinematic region of Q{sup 2}<2 GeV for the photon virtuality and photon-proton center of mass energies of 100

  5. Measurement of F_2^{c\\bar{c}} and F_2^{b\\bar{b}} at Low Q^2 and x using the H1 Vertex Detector at HERA

    CERN Document Server

    Aktas, A.; Anthonis, T.; Aplin, S.; Asmone, A.; Astvatsatourov, A.; Babaev, A.; Backovic, S.; Bahr, J.; Baghdasaryan, A.; Baranov, P.; Barrelet, E.; Bartel, W.; Baudrand, S.; Baumgartner, S.; Becker, J.; Beckingham, M.; Behnke, O.; Behrendt, O.; Belousov, A.; Berger, Ch.; Berger, N.; Bizot, J.C.; Boenig, M.-O.; Boudry, V.; Bracinik, J.; Brandt, G.; Brisson, V.; Brown, D.P.; Bruncko, D.; Busser, F.W.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A.J.; Caron, S.; Cassol-Brunner, F.; Cerny, K.; Cerny, V.; Chekelian, V.; Contreras, J.G.; Coughlan, J.A.; Cox, B.E.; Cozzika, G.; Cvach, J.; Dainton, J.B.; Dau, W.D.; Daum, K.; de Boer, Y.; Delcourt, B.; De Roeck, A.; Desch, K.; De Wolf, E.A.; Diaconu, C.; Dodonov, V.; Dubak, A.; Eckerlin, Guenter; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Ellerbrock, M.; Erdmann, W.; Essenov, S.; Falkewicz, A.; Faulkner, P.J.W.; Favart, L.; Fedotov, A.; Felst, R.; Ferencei, J.; Finke, L.; Fleischer, M.; Fleischmann, P.; Fleming, Y.H.; Flucke, G.; Fomenko, A.; Foresti, I.; Franke, G.; Frisson, T.; Gabathuler, E.; Garutti, E.; Gayler, J.; Gerlich, C.; Ghazaryan, Samvel; Ginzburgskaya, S.; Glazov, A.; Glushkov, I.; Goerlich, L.; Goettlich, M.; Gogitidze, N.; Gorbounov, S.; Goyon, C.; Grab, C.; Greenshaw, T.; Gregori, M.; Grell, B.R.; Grindhammer, Guenter; Gwilliam, C.; Haidt, D.; Hajduk, L.; Hansson, M.; Heinzelmann, G.; Henderson, R.C.W.; Henschel, H.; Henshaw, O.; Herrera, G.; Hildebrandt, M.; Hiller, K.H.; Hoffmann, D.; Horisberger, R.; Hovhannisyan, A.; Hreus, T.; Hussain, S.; Ibbotson, M.; Ismail, M.; Jacquet, M.; Janauschek, L.; Janssen, X.; Jemanov, V.; Jonsson, L.; Johnson, D.P.; Jung, Andreas Werner; Jung, H.; Kapichine, M.; Katzy, J.; Keller, N.; Kenyon, I.R.; Kiesling, Christian M.; Klein, M.; Kleinwort, C.; Klimkovich, T.; Kluge, T.; Knies, G.; Knutsson, A.; Korbel, V.; Kostka, P.; Krastev, K.; Kretzschmar, J.; Kropivnitskaya, A.; Kruger, K.; Kuckens, J.; Landon, M.P.J.; Lange, W.; Lastovicka, T.; Lastovicka-Medin, G.; Laycock, P.; Lebedev, A.; Leibenguth, G.; Lendermann, V.; Levonian, S.; Lindfeld, L.; Lipka, K.; Liptaj, A.; List, B.; Lobodzinska, E.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Lucaci-Timoce, A.-I.; Lueders, H.; Luke, D.; Lux, T.; Lytkin, L.; Makankine, A.; Malden, N.; Malinovski, E.; Mangano, S.; Marage, P.; Marshall, R.; Martisikova, M.; Martyn, H.-U.; Maxeld, S.J.; Meer, D.; Mehta, A.; Meier, K.; Meyer, A.B.; Meyer, H.; Meyer, J.; Mikocki, S.; Milcewicz-Mika, I.; Milstead, D.; Mladenov, D.; Mohamed, A.; Moreau, F.; Morozov, A.; Morris, J.V.; Mozer, Matthias Ulrich; Muller, K.; Murin, P.; Nankov, K.; Naroska, B.; Naumann, Th.; Newman, Paul R.; Niebuhr, C.; Nikiforov, A.; Nikitin, D.; Nowak, G.; Nozicka, M.; Oganezov, R.; Olivier, B.; Olsson, J.E.; Osman, S.; Ozerov, D.; Palichik, V.; Panagoulias, I.; Papadopoulou, T.; Pascaud, C.; Patel, G.D.; Peez, M.; Perez, E.; Perez-Astudillo, D.; Perieanu, A.; Petrukhin, A.; Pitzl, D.; Placakyte, R.; Portheault, B.; Povh, B.; Prideaux, P.; Raicevic, N.; Reimer, P.; Rimmer, A.; Risler, C.; Rizvi, E.; Robmann, P.; Roland, B.; Roosen, R.; Rostovtsev, A.; Rurikova, Z.; Rusakov, S.; Salvaire, F.; Sankey, D.P.C.; Sauvan, E.; Schatzel, S.; Schilling, F.-P.; Schmidt, S.; Schmitt, S.; Schmitz, C.; Schoeffel, L.; Schoning, A.; Schultz-Coulon, H.-C.; Sedlak, K.; Sefkow, F.; Shaw-West, R.N.; Sheviakov, I.; Shtarkov, L.N.; Sloan, T.; Smirnov, P.; Soloviev, Y.; South, D.; Spaskov, V.; Specka, Arnd E.; Stella, B.; Stiewe, J.; Strauch, I.; Straumann, U.; Tchoulakov, V.; Thompson, Graham; Thompson, P.D.; Tomasz, F.; Traynor, D.; Truoel, Peter; Tsakov, I.; Tsipolitis, G.; Tsurin, I.; Turnau, J.; Tzamariudaki, E.; Urban, Marcel; Usik, A.; Utkin, D.; Valkar, S.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Vargas Trevino, A.; Vazdik, Y.; Veelken, C.; Vest, A.; Vinokurova, S.; Volchinski, V.; Vujicic, B.; Wacker, K.; Wagner, J.; Weber, G.; Weber, R.; Wegener, D.; Werner, C.; Werner, N.; Wessels, M.; Wessling, B.; Wigmore, C.; Wissing, Ch.; Wolf, R.; Wunsch, E.; Xella, S.; Yan, W.; Yeganov, V.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhelezov, A.; Zhokin, A.; Zhu, Y.C.; Zimmermann, J.; Zimmermann, T.; Zohrabyan, H.; Zomer, F.

    2006-01-01

    Measurements are presented of inclusive charm and beauty cross sections in e^+p collisions at HERA for values of photon virtuality 12 \\le Q^2 \\le 60 GeV^2 and of the Bjorken scaling variable 0.0002 \\le x \\le 0.005. The fractions of events containing charm and beauty quarks are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured by the H1 vertex detector. Values for the structure functions F_2^{c\\bar{c}} and F_2^{b\\bar{b}} are obtained. This is the first measurement of F_2^{b\\bar{b}} in this kinematic range. The results are found to be compatible with the predictions of perturbative quantum chromodynamics and withprevious measurements of F_2^{c\\bar{c}}.

  6. The H1 liquid argon calorimeter system

    International Nuclear Information System (INIS)

    Andrieu, B.; Babayev, A.; Ban, J.

    1993-06-01

    The liquid argon calorimeter of the H1 detector presently taking data at the HERA ep - collider at DESY, Hamburg, is described here. The main physics requirements and the most salient design features relevant to this calorimeter are given. The aim to have smooth and hermetic calorimetric coverage over the polar angular range 4 ≤ θ ≤ 154 is achieved by a single liquid argon cryostat containing calorimeter stacks structured in wheels and octants for easy handling. The absorber materials used are lead in the electromagnetic part and stainless steel in the hadronic part. The read-out system is pipelined to reduce the dead time induced by the high trigger rate expected at the HERA collider where consecutive bunches are separated in time by 96 ns. The main elements of the calorimeter, such as the cryostat, with its associated cryogenics, the stack modules, the read-out, calibration and trigger electronics as well as the data acquisition system are described. Performance results from data taken in calibration runs with full size H1 calorimeter stacks at a CERN test beam, as well as results from data collected with the complete H1 detector using cosmic rays during the initial phase of ep operations are presented. The observed energy resolutions and linearities are well in agreement with the requirements. (orig.)

  7. The H1 forward muon spectrometer

    International Nuclear Information System (INIS)

    Kenyon, I.R.; Phillips, H.; Cronstroem, H.I.; Hedberg, V.; Jacobsson, C.; Joensson, L.; Lohmander, H.; Nyberg, M.; Biddulph, P.; Finnegan, P.; Foster, J.; Gilbert, S.; Hilton, C.; Ibbotson, M.; Mehta, A.; Sutton, P.; Stephens, K.; Thompson, R.

    1993-02-01

    The H1 detector started taking data at the electron- proton collider HERA in the beginning of 1992. In HERA 30 GeV electrons collide with 820 GeV protons giving a strong boost of the centre-of-mass system in the direction of the proton, also called the forward region. For the detection of high momentum muons in this region a muon spectrometer has been constructed, consisting of six drift chamber planes, three either side of a toroidal magnet. A first brief description of the system and its main parameters as well as the principles for track reconstruction and Τ 0 determination is given. (orig.)

  8. H1 in RSA galaxies

    Science.gov (United States)

    Richter, OTTO-G.

    1993-01-01

    The original Revised Shapley-Ames (RSA) galaxy sample of almost 1300 galaxies has been augmented with further bright galaxies from the RSA appendix as well as newer galaxy catalogs. A complete and homogeneous, strictly magnitude-limited all-sky sample of 2345 galaxies brighter than 13.4 in apparent blue magnitude was formed. New 21 cm H1 line observations for more than 600 RSA galaxies have been combined with all previously available H1 data from the literature. This new extentise data act allows detailed tests of widely accepted 'standard' reduction and analysis techniques.

  9. The H1 forward proton spectrometer at HERA

    International Nuclear Information System (INIS)

    Esch, P. van; Kapichine, M.; Morozov, A.; Spaskov, V.; Bartel, W.; List, B.; Mahlke-Krueger, H.; Schroeder, V.; Wilksen, T.; Buesser, F.W.; Geske, K.; Karschnik, O.; Niebergall, F.; Riege, H.; Schuett, J.; Staa, R. van; Wittek, C.; Dau, D.; Newton, D.; Kotelnikov, S.K.; Lebedev, A.; Rusakov, S.; Astvatsatourov, A.; Baehr, J.; Harder, U.; Hiller, K.; Hoffmann, B.; Luedecke, H.; Nahnhauer, R.

    2000-01-01

    The forward proton spectrometer is part of the H1 detector at the HERA collider. Protons with energies above 500 GeV and polar angles below 1 mrad can be detected by this spectrometer. The main detector components are scintillating fiber detectors read out by position-sensitive photo-multipliers. These detectors are housed in the so-called Roman Pots which allow them to be moved close to the circulating proton beam. Four Roman Pot stations are located at distances between 60 and 90 m from the interaction point

  10. The H1 forward proton spectrometer at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Esch, P. van; Kapichine, M.; Morozov, A.; Spaskov, V.; Bartel, W.; List, B.; Mahlke-Krueger, H.; Schroeder, V.; Wilksen, T.; Buesser, F.W.; Geske, K.; Karschnik, O.; Niebergall, F.; Riege, H.; Schuett, J.; Staa, R. van; Wittek, C.; Dau, D.; Newton, D.; Kotelnikov, S.K.; Lebedev, A.; Rusakov, S.; Astvatsatourov, A.; Baehr, J.; Harder, U.; Hiller, K. E-mail: hiller@ifh.de; Hoffmann, B.; Luedecke, H.; Nahnhauer, R

    2000-05-21

    The forward proton spectrometer is part of the H1 detector at the HERA collider. Protons with energies above 500 GeV and polar angles below 1 mrad can be detected by this spectrometer. The main detector components are scintillating fiber detectors read out by position-sensitive photo-multipliers. These detectors are housed in the so-called Roman Pots which allow them to be moved close to the circulating proton beam. Four Roman Pot stations are located at distances between 60 and 90 m from the interaction point.

  11. H1 antihistamines and driving

    OpenAIRE

    Florin-Dan, Popescu

    2008-01-01

    Driving performances depend on cognitive, psychomotor and perception functions. The CNS adverse effects of some H1 antihistamines can alter the patient ability to drive. Data from studies using standardized objective cognitive and psychomotor tests (Choice Reaction Time, Critical Flicker Fusion, Digital Symbol Substitution Test), functional brain imaging (Positron Emission Tomography, functional Magnetic Resonance Imaging), neurophysiological studies (Multiple Sleep Latency Test, auditory and...

  12. Data logging and online reconstruction in H1

    International Nuclear Information System (INIS)

    Fuhrmann, P.; Gerhards, R.; Kruener-Marquis, U.; Olsson, J.E.; Szkutnik, Z.

    1994-01-01

    In spring 1992, the H1 detector at the HERA electron proton collider at DESY came into operation. The high bunch crossing rate and, correspondingly, the large data volumes are placing demanding requirements on the data logging and event reconstruction. Both tasks are performed on an SGI Challenge series computer. This note reviews the development and the experience with the data logging and online reconstruction in H1

  13. Search on charginos and neutralinos with the L3 detector at LEP; Recherche de charginos et de neutralinos avec le detecteur L3 au LEP

    Energy Technology Data Exchange (ETDEWEB)

    Chereau, Xavier [Laboratoire d`Annecy-le-vieux de physique des particules, Grenoble-1 Univ., 74 Annecy (France)

    1998-04-30

    This work presents an experimental search for supersymmetric particles, the charginos and the neutralinos, at center of mass energies {radical} 161, 172 and 183 GeV, with the L3 detector at the e{sup +}e{sup -} collider LEP. Assuming R-parity conservation, SUSY events have a large missing energy, carried by the lightest supersymmetric particle (LSP), which allow us to distinguish them from standard events. Then, for all the studied final states and all the energies, we optimized the selections in order to have the best signal-to-noise ratio. No excess of events were observed with respect to the standard model predictions. We set upper limits on the chargino and neutralino production cross sections. In the frame of the constraint MSSM, these results were combined with the results from the L3 slepton analyses to set lower limits on the chargino and neutralino masses: particularly, we exclude a neutralino {chi}{sub 1}{sup 0} bar lighter than 25.9 GeV/c{sup 2} (95% C.L.). This result plays an important role for the interpretation of the dark matter in universe. The search for events with missing energy needs a detector with a good hermeticity. At the end of 1995, a new electromagnetic calorimeter was installed in the L3 experiment. Here we present the improvements of performances and the calibration of this detector composed of 48 bricks made with lead and scintillating fibers (SPACAL) 71 refs., 104 figs., 21 tabs.

  14. H1 antihistamines and driving.

    Science.gov (United States)

    Popescu, Florin Dan

    2008-01-01

    Driving performances depend on cognitive, psychomotor and perception functions. The CNS adverse effects of some H1 antihistamines can alter the patient ability to drive. Data from studies using standardized objective cognitive and psychomotor tests (Choice Reaction Time, Critical Flicker Fusion. Digital Symbol Substitution Test), functional brain imaging (Positron Emission Tomography, functional Magnetic Resonance Imaging), neurophysiological studies (Multiple Sleep Latency Test, auditory and visual evoked potentials), experimental simulated driving (driving simulators) and real driving studies (the Highway Driving Test, with the evaluation of the Standard Deviation Lateral Position, and the Car Following Test, with the measurement of the Brake Reaction Time) must be discussed in order to classify a H1 antihistamine as a true non-sedating one.

  15. Research of supersymmetric particles in the experience H1; Recherche de particules supersymetriques dans l`experience H1

    Energy Technology Data Exchange (ETDEWEB)

    Perez, E

    1996-06-17

    The study exposed in this thesis concerns a supersymmetrical extension of the Standard Model where the R-parity (a new quantum number) is not conserved. The principle results, how this analysis can be generalised and what it is possible to get with more luminosity are detailed; then, the potential for HERA to produce others kind of supersymmetric particles is shown. (N.C.). 98 refs., 146 figs., 17 tabs.

  16. The search for charginos and neutralinos with the ATLAS detector at LHC; La recherche des charginos et des neutralinos avec le detecteur Atlas au LHC

    Energy Technology Data Exchange (ETDEWEB)

    Muanza, G.S.

    1996-05-01

    This thesis concerns the prospective study to evidence the supersymmetry with the ATLAS detector at the CERN Large Hadron Collider (LHC) by searching for the disintegration of chargino-neutralino pairs into three leptons. The analysis of this channel is performed through a rapid simulation of the detector used for the signal processing and to process the background (from the standard model and from the MSSM) which may hinder the detection. The results are given for different configurations of LHC: at low energy ({radical}s = 9.3 TeV), at high energy ({radical}s = 14 TeV), at low luminosity (L = 10 sup 3 sup 3 cm sup -2 sup -1), at high luminosity (L = 10 sup 3 sup 4 cm sup -2 sup -1). Finally, we propose an original method allowing the estimation of the gluino mass (an essential parameter of the MSSM) as well as that of all the charginos and neutralinos. This method is of course approximated but it relies on a unique experimental measurement and permits the rebuilding of the whole mass spectrum of the MSSM jauginos to be performed with a worthy precision. The experimental part of this thesis deals with the tests performed on the new photomultipliers (PMTs) HAMAMATSU R5900 which are foreseen for the outfit of the ATLAS tile calorimeter TICAL. The results of these tests show that the PMTs are in conformity with the specifications of the reading of TICAL. (N.T.).

  17. Multijet events in DELPHI detector at LEP, application to the search for supersymmetric particles; Evenements multijets a LEP200 dans DELPHI application a la recherche de particules supersymetriques

    Energy Technology Data Exchange (ETDEWEB)

    Poireau, V

    2001-04-01

    A search for multijet events was performed in the DELPHI detector at LEP. These events are predicted by supersymmetry with R-parity violation. An integrated luminosity of 608 pb{sup -1} was collected in the detector, with a centre of mass energy from 189 GeV to 209 GeV. First of all, pair production of neutralinos and charginos was searched for in the data. These events give 6 to 10 jet final states via a R-parity violating {lambda}'' coupling. During the analysis, a discrepancy was observed in the high number of jet region. It was shown that this disagreement comes from an inaccurate modelization of hadronization in the generators. A correction was applied on the simulation to take this systematic effect into account. The analysis showed no presence of signal, which, in the framework of the mSUGRA model, can be translated into the following limits (at 95 % confidence level): M{sub {chi}{sub 1}{sup {approx}{+-}}} > 102,5 GeV/c{sup 2} and M{sub {chi}{sub 1}{sup {approx}0}} > 38 GeV/c{sup 2}. In addition, supersymmetry with R-parity violation, via A' couplings and a squark exchange, predicts a possible production of a t quark together with a light quark. A search for these events was done in the hadronic channel (four jets) and in the semi-leptonic channel (two jets and two leptons). No excess was found in the data with respect to the standard model expectations, which translates into a 95 % confidence level limit on the coupling product: {lambda}'{sub 1jk}{lambda}'{sup *}{sub 13k} < 0,043 (for j, k = [1;2] and for a squark mass of 100 GeV/c{sup 2}). (author)

  18. Measurement of the D{sup *{+-}} meson cross section and extraction of the charm contribution, F{sup c}{sub 2}(x, Q{sup 2}), to the proton structure in deep inelastic ep scattering with the H1 detector at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Andreas Werner

    2009-01-15

    Inclusive production of D{sup *} mesons in deep inelastic scattering at HERA is studied using data taken with the H1 detector in the years 2004 to 2007 corresponding to an integrated luminosity of 347 pb{sup -1}. The measurement covers the region 51.5 GeV and vertical stroke {eta}(D{sup *}) vertical stroke < 1.5. The present measurement is based on an eightfold increased statistics compared to the previous H1 publication and provides a significantly reduced systematic error. Single and double-differential cross sections are compared to leading and next-to-leading order perturbative QCD predictions. The charm contribution, F{sup c}{sub 2} (x,Q{sup 2}), to the proton structure in different QCD evolution schemes is derived from the D{sup *} cross sections and compared to next-to-leading order perturbative QCD predictions. This F{sup c}{sub 2} measurement is performed using a factor of 18 more data compared to the previous H1 publication. The present thesis additionally describes a successfully completed hardware project: The commissioning and optimisation of the third level of the H1 Fast Track Trigger (FTT), which was fully operational from 2006 onwards. The FTT is integrated in the first three levels of the H1 trigger system and provides enhanced selectivity for events with charged particles. The third trigger level of the FTT performs a track-based event reconstruction within a latency of about 100 {mu}s. The third trigger level of the FTT is realised by a farm of PowerPC boards. Furthermore, the FTT simulation is now incorporated into the H1 trigger simulation. (orig.)

  19. Phenomenology and research for squarks at LEP200 with the DELPHI detector; Phenomenologie et recherche de squarks a LEP200 avec le detecteur delphi

    Energy Technology Data Exchange (ETDEWEB)

    Gris, Ph [CEA Saclay, 91 - Gif-sur-Yvette (France). Dept. d` Astrophysique, de la Physique des Particules, de la Physique Nucleaire et de l` Instrumentation Associee; [Paris-6 Univ., 75 (France)

    1998-05-01

    This thesis is devoted to the study of some supersymmetric quarks such as s-top and s-bottom. This investigation field is all the more interesting since the weak mass of these squarks could be explained by the strong Yukawa coupling between top and bottom quarks. The theoretical framework is defined and the insufficiency of the standard model is highlighted. Different models such as MSSM, supergravity models in which supersymmetry is a global symmetry are described. Squark phenomenology at LEP200 is exposed and the most likely disintegration channels for stop and s-bottom quarks are investigated in various models (MSSM, mSUGRA, supergravity models with light gravitino). The experimental tool used in this work, DELPHI detector is presented, the main elements involved in the search for squarks are precisely described. The last part of this thesis is dedicated to the effective search for squarks, the analysis deals with the energies: {radical}s=161, 172 and 183 GeV for which the luminosity values collected by DELPHI are respectively 9.7, 10 and 54 pb{sup -1}. The results are interpreted within the frameworks of different supersymmetric theories 184 refs.

  20. H1N1 influenza (Swine flu)

    Science.gov (United States)

    Swine flu; H1N1 type A influenza ... The H1N1 virus is now considered a regular flu virus. It is one of the three viruses included in the regular (seasonal) flu vaccine . You cannot get H1N1 flu virus from ...

  1. The H1 calorimetry: Performance and upgrade program

    International Nuclear Information System (INIS)

    Borras, K.

    1995-04-01

    The energies of particles are measured in the H1 detector with four different calorimeters. Their designs, which are optimized for their particular requirements, are briefly described. Their performance is characterized in terms of their operational stability, the precision of their energy scale and their trigger functionality. The most important among the four calorimeters is the large liquid argon calorimeter and therefore most emphasis is given to the description of this component. (orig.)

  2. Résultats de recherche | Page 441 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Initiative des conseils subventionnaires de la recherche scientifique en Afrique subsaharienne. Les conseils subventionnaires de la recherche scientifique sont essentiels au financement et à la promotion de la recherche et de l'innovation. Initiative.

  3. Luminosity measurement in H1; Mesure de la luminosite pour l'experience H1

    Energy Technology Data Exchange (ETDEWEB)

    Frisson, T

    2006-10-15

    At HERA, luminosity is determined on-line and bunch by bunch by measuring the Bremsstrahlung spectrum from e-p collisions. The Hl collaboration has built a completely new luminosity system in order to sustain the harsh running conditions after the fourfold luminosity increase. Namely, the higher synchrotron radiation doses and the increased event pile-up have governed the design of the two major components, a radiation resistant quartz-fibre electro-magnetic calorimeter, and a fast read-out electronic with on-line energy histogram loading at a rate of 500 kHz. The group was in charge of the electronic and the on-line data analysis of the new luminosity system. In this thesis, I present analysis tools and methods to improve the precision of the luminosity measurement. The energy scale and acceptance calculation methods set out in this thesis permit these values to be determined every four minutes, to an accuracy of 0.5 parts per thousand for the energy scale and 2 parts per thousand for the acceptance. From these results, the degree of accuracy obtained on the luminosity measurement is between 6.5 and 9.5 parts per thousand. These results are currently undergoing validation, with the aim of becoming the standard H1 method. I also studied quasi-elastic Compton events to cross-check the luminosity measurement using the 2003- 2004 and 2005 data. Indeed, this process has a well calculable cross section and a clear experimental signature. The leptonic final state consists of a coplanar e-gamma system, both observable in the central H1 detector. (author)

  4. Outils de recherche | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Nos documents de formation et guides aident à perfectionner les compétences et les connaissances afin d'améliorer la qualité de la recherche au service du développement. Nous offrons également un accès gratuit à notre base de données sur les projets de recherche que nous subventionnons, IDRIS+, et à notre ...

  5. The symbiotic star H1-36

    International Nuclear Information System (INIS)

    Allen, D.A.

    1983-01-01

    Optical and infrared spectrophotometry is presented of the high-excitation emission-line star H1-36. The presence of a variable M giant is established: H1-36 may therefore be classified as a symbiotic star. The observations are interpreted in terms of the usual binary model for symbiotic stars, namely that an unseen star is heated by accretion of gas from its companion M giant. (author)

  6. Résultats de recherche | Page 19 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les conseils subventionnaires de la recherche scientifique sont essentiels au financement et à la promotion de la recherche et de l'innovation, particulièrement dans les réseaux nationaux de recherche scientifique d'Afrique. Projet. Renforcer les capacités de gestion de la recherche des conseils subventionnaires de la ...

  7. Résultats de recherche | Page 2 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les conseils subventionnaires de la recherche scientifique sont essentiels au financement et à la promotion de la recherche et de l'innovation, particulièrement dans les réseaux nationaux de recherche scientifique d'Afrique. Projet. Renforcer les capacités de gestion de la recherche des conseils subventionnaires de la ...

  8. Homologous histamine H1 receptor desensitization results in reduction of H1 receptor agonist efficacy

    NARCIS (Netherlands)

    Leurs, R; Smit, M J; Bast, A; Timmerman, H

    1991-01-01

    Prolonged exposure of the guinea-pig intestinal longitudinal smooth muscle to histamine caused homologous desensitization of the H1 receptor, which led to reduced H1 receptor-mediated production of [3H]inositol phosphates as well as to reduced H1 agonist-induced contractions. [3H]Mepyramine binding

  9. The H1 Data Preservation Project

    International Nuclear Information System (INIS)

    South, D M; Steder, M

    2012-01-01

    The H1 data preservation project was started in 2009 as part of the global data preservation initiative in high-energy physics, DPHEP. In order to retain the full potential for future improvements, the H1 Collaboration aims for level 4 of the DPHEP recommendations, which requires the full simulation and reconstruction chain as well as the data to be preserved for future analysis. A major goal of the H1 project is therefore to provide secure, long-lived and validated access to the H1 data and analysis software, which is realised in collaboration with DESY-IT using virtualisation techniques. By implementing such a system, it is hoped that the lifetime of the unique ep collision data from HERA will be extended, providing the possibility for novel analysis in the future. The preservation of the data and software is performed alongside a consolidation programme of digital and non-digital documentation, some of which dates back to the early 1980s. A new organisational model of the H1 Collaboration, reflecting the change to the long term phase, is to be adopted in July 2012.

  10. The H1 lead/scintillating-fibre calorimeter

    International Nuclear Information System (INIS)

    Appuhn, R.D.; Arndt, C.; Barrelet, E.

    1996-08-01

    The backward region of the H1 detector has been upgraded in order to provide improved measurement of the scattered electron in deep inelastic scattering events. The centerpiece of the upgrade is a high-resolution lead/scintillating-fibre calorimeter. The main design goals of the calorimeter are: good coverage of the region close to the beam pipe, high angular resolution and energy resolution of better than 2% for 30 GeV electrons. The calorimeter should be capable of providing coarse hadronic energy measurement and precise time information to suppress out-of-time background events at the first trigger level. It must be compact due to space restrictions. These requirements were fulfilled by constructing two separate calorimeter sections. The inner electromagnetic section is made of 0.5 mm scintillating plastic fibres embedded in a lead matrix. Its lead-to-fibre ratio is 2.3:1 by volume. The outer hadronic section consists of 1.0 mm diameter fibres with a lead-to-fibre ratio of 3.4:1. The mechanical construction of the new calorimeter and its assembly in the H1 detector are described. (orig.)

  11. The H1 lead/scintillating-fibre calorimeter

    International Nuclear Information System (INIS)

    Appuhn, R.-D.; Arndt, C.; Barrelet, E.

    1997-01-01

    The backward region of the H1 detector has been upgraded in order to provide improved measurement of the scattered electron in deep inelastic scattering events. The centerpiece of the upgrade is a high-resolution lead/scintillating-fibre calorimeter. The main design goals of the calorimeter are: good coverage of the region close to the beam pipe, high angular resolution and energy resolution of better than 2% for 30 GeV electrons. The calorimeter should be capable of providing coarse hadronic energy measurement and precise time information to suppress out-of-time background events at the first trigger level. It must be compact due to space restrictions. These requirements were fulfilled by constructing two separate calorimeter sections. The inner electromagnetic section is made of 0.5 mm scintillating plastic fibres embedded in a lead matrix. Its lead-to-fibre ratio is 2.3:1 by volume. The outer hadronic section consists of 1.0 mm diameter fibres with a lead-to-fibre ratio of 3.4:1. The mechanical construction of the new calorimeter and its assembly in the H1 detector are described. (orig.)

  12. Antiviral Prophylaxis and H1N1

    Centers for Disease Control (CDC) Podcasts

    2011-07-14

    Dr. Richard Pebody, a consultant epidemiologist at the Health Protection Agency in London, UK, discusses the use of antiviral post-exposure prophylaxis and pandemic H1N1.  Created: 7/14/2011 by National Center for Emerging Zoonotic and Infectious Diseases (NCEZID).   Date Released: 7/18/2011.

  13. Pandemic influenza A (H1N1)

    African Journals Online (AJOL)

    ... in Port Shepstone, South Africa. Introduction. Influenza A (H1N1) 2009 'swine flu' variant is currently a global pandemic.1 The infection associated with this virus is usually a mild, self-limiting illness. However, it may progress to severe pneumonia requiring intensive care unit (ICU) therapy in 31% of patients.2 This may.

  14. Antiallergic effects of H1-receptor antagonists.

    Science.gov (United States)

    Baroody, F M; Naclerio, R M

    2000-01-01

    The primary mechanism of antihistamine action in the treatment of allergic diseases is believed to be competitive antagonism of histamine binding to cellular receptors (specifically, the H1-receptors), which are present on nerve endings, smooth muscles, and glandular cells. This notion is supported by the fact that structurally unrelated drugs antagonize the H1-receptor and provide clinical benefit. However, H1-receptor antagonism may not be their sole mechanism of action in treating allergic rhinitis. On the basis of in vitro and animal experiments, drugs classified as H1-receptor antagonists have long been recognized to have additional pharmacological properties. Most first-generation H1-antihistamines have anticholinergic, sedative, local anaesthetic, and anti-5-HT effects, which might favourably affect the symptoms of the allergic response but also contribute to side-effects. These additional properties are not uniformly distributed among drugs classified as H1-receptor antagonists. Azatadine, for example, inhibits in vitro IgE-mediated histamine and leukotriene (LT) release from mast cells and basophils. In human challenge models, terfenadine, azatadine, and loratadine reduce IgE-mediated histamine release. Cetirizine reduces eosinophilic infiltration at the site of antigen challenge in the skin, but not the nose. In a nasal antigen challenge model, cetirizine pretreatment did not affect the levels of histamine and prostaglandin D2 recovered in postchallenge lavages, whereas the levels of albumin, N-tosyl-L-arginine methyl ester (TAME) esterase activity, and LTs were reduced. Terfenadine, cetirizine, and loratadine blocked allergen-induced hyperresponsiveness to methacholine. In view of the complexity of the pathophysiology of allergy, a number of H1 antagonists with additional properties are currently under development for allergic diseases. Mizolastine, a new H1-receptor antagonist, has been shown to have additional actions that should help reduce the

  15. Antifungal properties of wheat histones (H1-H4) and purified wheat histone H1

    Science.gov (United States)

    Wheat (Triticum sp.) histones H1, H2, H3, and H4 were extracted. H1 was further purified. Their activities against fungi with varying degrees of wheat pathogenicity were determined. They included Aspergillus flavus, A. fumigatus, A. niger, F. oxysporum, F. verticillioides, F. solani, F. graminearu...

  16. Symbiotic star H1-36

    Energy Technology Data Exchange (ETDEWEB)

    Allen, D A

    1983-01-01

    It is suggested that H1-36 should be classified as a symbiotic star rather than a planetary nebula. Evidence of a cool giant now exists and the high-excitation emission-line spectrum resembles the spectra of many symbiotic stars. The optical spectrum, radio spectrum, high spectral index of +0.9 and computed mass-loss rate are among the features discussed.

  17. The symbiotic star H1-36

    International Nuclear Information System (INIS)

    Allen, D.A.

    1983-01-01

    It is suggested that H1-36 should be classified as a symbiotic star rather than a planetary nebula. Evidence of a cool giant now exists and the high-excitation emission-line spectrum resembles the spectra of many symbiotic stars. The optical spectrum, radio spectrum, high spectral index of +0.9 and computed mass-loss rate are among the features discussed

  18. Photoperiod-H1 (Ppd-H1) Controls Leaf Size1[OPEN

    Science.gov (United States)

    Digel, Benedikt; Tavakol, Elahe; Verderio, Gabriele; Xu, Xin

    2016-01-01

    Leaf size is a major determinant of plant photosynthetic activity and biomass; however, it is poorly understood how leaf size is genetically controlled in cereal crop plants like barley (Hordeum vulgare). We conducted a genome-wide association scan for flowering time, leaf width, and leaf length in a diverse panel of European winter cultivars grown in the field and genotyped with a single-nucleotide polymorphism array. The genome-wide association scan identified PHOTOPERIOD-H1 (Ppd-H1) as a candidate gene underlying the major quantitative trait loci for flowering time and leaf size in the barley population. Microscopic phenotyping of three independent introgression lines confirmed the effect of Ppd-H1 on leaf size. Differences in the duration of leaf growth and consequent variation in leaf cell number were responsible for the leaf size differences between the Ppd-H1 variants. The Ppd-H1-dependent induction of the BARLEY MADS BOX genes BM3 and BM8 in the leaf correlated with reductions in leaf size and leaf number. Our results indicate that leaf size is controlled by the Ppd-H1- and photoperiod-dependent progression of plant development. The coordination of leaf growth with flowering may be part of a reproductive strategy to optimize resource allocation to the developing inflorescences and seeds. PMID:27457126

  19. Photoperiod-H1 (Ppd-H1) Controls Leaf Size.

    Science.gov (United States)

    Digel, Benedikt; Tavakol, Elahe; Verderio, Gabriele; Tondelli, Alessandro; Xu, Xin; Cattivelli, Luigi; Rossini, Laura; von Korff, Maria

    2016-09-01

    Leaf size is a major determinant of plant photosynthetic activity and biomass; however, it is poorly understood how leaf size is genetically controlled in cereal crop plants like barley (Hordeum vulgare). We conducted a genome-wide association scan for flowering time, leaf width, and leaf length in a diverse panel of European winter cultivars grown in the field and genotyped with a single-nucleotide polymorphism array. The genome-wide association scan identified PHOTOPERIOD-H1 (Ppd-H1) as a candidate gene underlying the major quantitative trait loci for flowering time and leaf size in the barley population. Microscopic phenotyping of three independent introgression lines confirmed the effect of Ppd-H1 on leaf size. Differences in the duration of leaf growth and consequent variation in leaf cell number were responsible for the leaf size differences between the Ppd-H1 variants. The Ppd-H1-dependent induction of the BARLEY MADS BOX genes BM3 and BM8 in the leaf correlated with reductions in leaf size and leaf number. Our results indicate that leaf size is controlled by the Ppd-H1- and photoperiod-dependent progression of plant development. The coordination of leaf growth with flowering may be part of a reproductive strategy to optimize resource allocation to the developing inflorescences and seeds. © 2016 American Society of Plant Biologists. All rights reserved.

  20. Résultats de recherche | Page 33 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Renforcer les partenariats entre les conseils subventionnaires de la recherche scientifique d'Afrique et le secteur privé. Les conseils subventionnaires de la recherche scientifique sont essentiels au financement et à la promotion de la recherche et de l'innovation. Projet ...

  1. Résultats de recherche | Page 37 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Renforcer les partenariats entre les conseils subventionnaires de la recherche scientifique d'Afrique et le secteur privé. Les conseils subventionnaires de la recherche scientifique sont essentiels au financement et à la promotion de la recherche et de l'innovation.

  2. A diagnostic for 2D density profiles in Heliac H-1

    International Nuclear Information System (INIS)

    Howard, J.; Sharp, L.E.

    1989-01-01

    A novel multi-view scanning interferometer is described. An air turbine driven scanning rotating grating wheel is used to produce ∼ 30 distinct spatial channels in four equi-spaced views of the H-1 plasma. The interferometer signals, derived from just three detectors, are multiplexed in time with a resolution of ∼ 1 ms. 7 refs., 3 figs

  3. Bourse de recherche 2018 du CRDI | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Agriculture et sécurité alimentaire, Changements climatiques, Initiative de recherche concertée sur l'adaptation en Afrique et en Asie, Emploi et croissance, Alimentation, environnement et santé, Fondements pour l'innovation, Gouvernance et justice, Fonds d'innovation en vaccins pour le bétail, Santé des mères et des ...

  4. Optimization of the ATLAS detector to search for the two-photon decaying Higgs boson at LHC; Optimisation du detecteur ATLAS pour la recherche du boson de Higgs se desintegrant en deux photons au LHC

    Energy Technology Data Exchange (ETDEWEB)

    Tisserand, V [Paris-11 Univ., 91 - Orsay (France). Lab. de l' Accelerateur Lineaire; [Universite de Paris Sud, 91 - Orsay (France)

    1997-02-03

    The two photon decay channel is the most clear and promising way to detect a Higgs boson of an intermediate mass between 80 GeV/c{sup 2} and 150 GeV/c{sup 2} at the future large proton collider of CERN (LHC). As the Higgs mass is narrow in this range, the observation of this channel relies on the performance of the electromagnetic calorimeter. A full simulation study has been performed to evaluate the discovery potential of the ATLAS detector. The results of this simulation have been confirmed by beam tests with a prototype. This simulation includes different contributions such as energy resolution sampling term, electronic and pile-up noise, global constant term and angular measurement of the two photon opening angle. The levels of the irreducible background from prompt di-photon production and the reducible background from jets with isolated leading neutrals pions have been estimated, taking into account the rejection capability of the detector. After the computation of the two photon invariant mass resolution, and the evaluation of signal and background rates, the discovery potential of the Higgs boson with the ATLAS detector was calculated. The Higgs can be discovered at five sigma confidence level after less than a year of data taking at LHC with the nominal luminosity of 10{sup 34} cm{sup -2}.s{sup -1} if the Higgs mass is between 100 GeV/c{sup 2} and 150 GeV/c{sup 2}. The Higgs mass window between 80 GeV/c{sup 2} and 150 GeV/c{sup 2} will be covered with an integrated luminosity of 3.10{sup 5} pb{sup -1}. In the case of the Minimal Supersymmetric Model (MSSM) the plane (m{sub A{sup 0}}, tan({beta})) will be fully explored if m{sub A{sup 0}} > 175 GeV/c{sup 2}. (author)

  5. H1 Grid production tool for large scale Monte Carlo simulation

    Energy Technology Data Exchange (ETDEWEB)

    Lobodzinski, B; Wissing, Ch [DESY, Hamburg (Germany); Bystritskaya, E; Vorobiew, M [ITEP, Moscow (Russian Federation); Karbach, T M [University of Dortmund (Germany); Mitsyn, S [JINR, Moscow (Russian Federation); Mudrinic, M, E-mail: bogdan.lobodzinski@desy.d [VINS, Belgrad (Serbia)

    2010-04-01

    The H1 Collaboration at HERA has entered the period of high precision analyses based on the final data sample. These analyses require a massive production of simulated Monte Carlo (MC) events. The H1 MC framework (H1MC) is a software for mass MC production on the LCG Grid infrastructure and on a local batch system created by H1 Collaboration. The aim of the tool is a full automatisation of the MC production workflow including management of the MC jobs on the Grid down to copying of the resulting files from the Grid to the H1 mass storage tape device. The H1 MC framework has modular structure, delegating a specific task to each module, including task specific to the H1 experiment: Automatic building of steer and input files, simulation of the H1 detector, reconstruction of particle tracks and post processing calculation. Each module provides data or functionality needed by other modules via a local database. The Grid jobs created for detector simulation and reconstruction from generated MC input files are fully independent and fault-tolerant for 32 and 64-bit LCG Grid architecture and in Grid running state they can be continuously monitored using Relational Grid Monitoring Architecture (R-GMA) service. To monitor the full production chain and detect potential problems, regular checks of the job state are performed using the local database and the Service Availability Monitoring (SAM) framework. The improved stability of the system has resulted in a dramatic increase in the production rate, which exceeded two billion MC events in 2008.

  6. H1-antihistamines in pregnancy and lactation.

    Science.gov (United States)

    Schatz, Michael

    2002-01-01

    Antihistamines may be used for the treatment of allergic rhinitis, upper respiratory infections, urticaria/angioedema, atopic dermatitis, and, rarely, as adjunctive treatment for anaphylaxis, during pregnancy. Because these illnesses may affect maternal comfort and safety as well as threaten the fetus directly (anaphylaxis) or indirectly, they often require therapy during pregnancy. Based on the information available to date, in this chapter we have attempted to provide rational guidelines for the gestational use of H1-receptor antagonists in a manner that will lead to the optimal well-being of both the mother and her infant. As more information becomes available, the recommendations herein may require modification. Although this chapter has dealt specifically with gestational management, a case can be made for considering this information when making therapeutic decisions in all women of childbearing potential. First, most pregnancies are unplanned, and the peak period of fetal vulnerability to drug-induced teratogenesis begins the day a woman's period is due. Second, during gestation, substantial alterations in a previously successful but not optimal-for-pregnancy chronic therapeutic regimen may be psychologically threatening to the patient and may lead to either uncontrolled disease or unanticipated side effects. Thus, pregnancy-appropriate regimens should ideally be discussed with all women of childbearing age as part of the informed therapeutic decision-making process.

  7. Data acquisition system realization for H1 experiment

    International Nuclear Information System (INIS)

    Del Buono, L.

    1989-06-01

    The acquisition and trigger system for H1 liquid argon calorimeter deals with severe constraints which have to be taken into account. We describe the system which results from these constraints, emphasizing the solutions adopted to meet the specificities of the detector and the difficult experimental conditions at HERA: high physical background (10 4-5 Hz), physics and background events pile up (10%), large crossing frequency of proton and electron bunches (10.4 MHz). Next, we present a detailed description of the acquisition and online control scheme used during the calorimetry tests in SPS beam, at CERN. This test system, prefiguring the final one (which will start to work at the end of 1989), includes a fast frontal processor CAB (taking charge of the electronics read out and sequencing, and furthermore producing simple histograms). The CAB is controlled by a Micro Vax computer which realizes the user interface, allowing a quick visualisation and verification of the acquired data, these functions being performed in multitasking environment [fr

  8. Protective efficacy of an inactivated Eurasian avian-like H1N1 swine influenza vaccine against homologous H1N1 and heterologous H1N1 and H1N2 viruses in mice.

    Science.gov (United States)

    Sui, Jinyu; Yang, Dawei; Qiao, Chuanling; Xu, Huiyang; Xu, Bangfeng; Wu, Yunpu; Yang, Huanliang; Chen, Yan; Chen, Hualan

    2016-07-19

    Eurasian avian-like H1N1 (EA H1N1) swine influenza viruses are prevalent in pigs in Europe and Asia, but occasionally cause human infection, which raises concern about their pandemic potential. Here, we produced a whole-virus inactivated vaccine with an EA H1N1 strain (A/swine/Guangxi/18/2011, SW/GX/18/11) and evaluated its efficacy against homologous H1N1 and heterologous H1N1 and H1N2 influenza viruses in mice. A strong humoral immune response, which we measured by hemagglutination inhibition (HI) and virus neutralization (VN), was induced in the vaccine-inoculated mice upon challenge. The inactivated SW/GX/18/11 vaccine provided complete protection against challenge with homologous SW/GX/18/11 virus in mice and provided effective protection against challenge with heterologous H1N1 and H1N2 viruses with distinctive genomic combinations. Our findings suggest that this EA H1N1 vaccine can provide protection against both homologous H1N1 and heterologous H1N1 or H1N2 virus infection. As such, it is an excellent vaccine candidate to prevent H1N1 swine influenza. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Search for Higgs Boson in the channel with missing energy with the detector ALEPH at LEP2; Recherche du Boson de Higgs dans le canal a energie manquante avec le detecteur ALEPH a LEP2

    Energy Technology Data Exchange (ETDEWEB)

    Kado, Marumi [Paris-6 Univ., 95 Paris (France)

    1999-04-20

    A search for the Standard Model Higgs boson in the channel e{sup +}e{sup -} {yields} H{nu}{nu}-bar is presented. An event selection method using Neural Network techniques is developed. The analysis is based on a 254 pb{sup -1} data sample taken at center-of-mass energies from {radical} s = 161 up to 189 GeV (from 1996 to 1998), by the ALEPH detector within the LEP2 program at CERN. The experimental systematic defects are studied and the corrections and uncertainties are evaluated. The study of this channel alone results in a mass lower limit of the Standard Model Higgs boson of 85.8 GeV/c{sup 2} with a sensitivity of 89 GeV/c{sup 2} at the 95% CL. Combined with all studied final states, the limit at 95% CL obtained is: m{sub H} > 90.2 GeV/c{sup 2} (observed) and m{sub H} > 95.7 GeV/c{sup 2} (expected). An interpolation of these results within the Minimal Supersymmetric Standard Model is presented along with the combination of all channels, including those originating from the associated production process (e{sup +}e{sup -} {yields} hA), leading to an exclusion at the 95% CL, for any value of tan{beta}{>=} 1, of the h and A neutral Higgs boson masses of: m{sub H} > 80.1 GeV/c{sup 2} (observed) and m{sub A} > 81.7 GeV/c{sup 2} (observed). (author)

  10. Detectors calibration and research of luminescent materials for non baryonic dark matter detection; Calibration de detecteurs et recherche de materiaux luminescents pour la detection de la matiere noire non baryonique

    Energy Technology Data Exchange (ETDEWEB)

    Messous, M.Y.

    1995-03-01

    This work is dedicated to the characterization of luminescent materials in order to build bolometers for the simultaneous detection of heat an light in the search for WIMPs (Weakly Interacting Massive Particles) candidates for non baryonic dark matter. These double bolometers should enable the identification and measurement of recoil ions after collision between a WIMPs and material nucleus. In our search for highly luminescent materials, we have studied the emission spectra, the time response and the spectra response resulting from laser excitation or ionizing particles bombardment of some crystals such as CaF{sub 2}(Eu), CaF{sub 2}, CeF{sub 3}(Ce) and In{sub 2}Si{sub 2}O{sub 7}. These studies were conducted down to liquid Helium temperature (4 K). After showing the good performance of CaF{sub 2}(Eu) scintillator, we have measured the quenching effect resulting from {sup 19}F and Ca ions recoil in CaF{sub 2}(Eu). This was done at the 14 MeV Tandem accelerator of Bruyeres-Le-Chatel with a pulsed neutron beam, simulating the WIMPs. The data obtained allowed the exploitation of the results of the BPRS (Beijing - Rome - Paris - Saclay) experiments carried out at Gran-Sasso. This results showed a gain of up to an order of magnitude in the exclusion graph of axially coupled WIMPs compared to NaI. With the apparatus developed at IPN Lyon (Nuclear Physical Institute of Lyon), we have also measured the ionization induced by Ge ion recoils in Germanium detector, which is one of the most promising crystals for WIMPs detection in the energy range of 2.8 keV-37.8 keV. An ionization efficiency of 24% to 29% was obtained. (author). refs., figs., tabs.

  11. Rechercher avec Google : quelques conseils

    OpenAIRE

    Ginouvès, Véronique

    2004-01-01

    Quoi de neuf ? (août 2006) : Toute la recherche Google sur une seule page : Le Googdesk : http://googdesk.com/ Google Trends Google Trends est un outil d'analyse de mots ou expressions clés, censé vous permettre de voir ce que le monde cherche ("See what the world is searching for''). Il compare et analyse dans un graphique l’usage et le comportement des mots clés dans le moteur sur deux années en arrière, et il spécifie cette utilisation par ville, pays et langue. http://www.google.com/tr...

  12. Recherche documentaire par titrage automatique

    OpenAIRE

    Lopez , Cédric; Prince , Violaine; Roche , Mathieu

    2011-01-01

    Nous proposons dans cet article un système facilitant la recherche d'information dans un ensemble de documents textuels, basé sur le titrage (et sous-titrage) automatique. Ce dernier peut se révéler crucial, par exemple, dans le cadre de la problématique de l'accessibilité des pages web (norme W3C). Notre processus de titrage automatique consiste à extraire des syntagmes nominaux pertinents dans les textes, pouvant constituer des titres ou sous-titres candidats. Une approche originale combina...

  13. 2009 H1N1 Flu Vaccine Facts

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Flu 2009 H1N1 Flu Vaccine Facts Past Issues / Fall 2009 Table of ... the H1N1 flu vaccine. 1 The 2009 H1N1 flu vaccine is safe and well tested. Clinical trials ...

  14. The H1 backward calorimeter BEMC and its inclusive electron trigger

    International Nuclear Information System (INIS)

    Ban, J.; Bauhoff, W.; Bruncko, D.; Brune, C.; Claassen, F.; Duhm, H.H.; Eisen, E.; Eschweiler, M.; Ferencei, J.; Fleischer, M.; Gaertner, W.; Gennis, M.; Glazov, A.; Griebel, R.; Guelck, C.; Harning, M.; Hartmann, T.; Hoelzke, U.; Javorek, M.; Kasselmann, H.P.; Krasny, M.W.; Krivan, F.; Krause, H.; Koch, J.; Kuehn, U.; Kurca, T.; Langkau, R.; Lipka, M.; Maracek, R.; Matysek, M.; Meier, K.; Murin, P.; Novak, T.; Olszowska, J.; Peppel, E.; Pichler, C.; Rathje, K.; Reimer, P.; Reinshagen, S.; Scobel, W.; Schirm, N.; Schrader, C.; Schrieber, S.; Seman, M.; Skvaril, P.; Spalek, J.; Wunderlich, R.; Zarbock, D.

    1996-01-01

    A sandwich type lead-scintillator electromagnetic calorimeter with wavelength shifter optical readout has been successfully operated at the DESY ep collider HERA in the H1 detector for three years. The mechanical design of the calorimeter together with the associated electronics and the inclusive electron trigger as well as its performance and stability in test beams and at the ep collider HERA are described in detail. (orig.)

  15. Résultats de recherche | Page 406 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Jeter des ponts enmatière de recherche en économie: John Whalley (Canada). Research in Action. Agrifood markets Biodiversity Crops Farming Systems Food security Gender. Lizzie Shumba, Malawi Intégrer la recherche au travail des agriculteurs. Research in Action. Water. Comment éviter la crise de l'eau. Research in ...

  16. Résultats de recherche | Page 81 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Valorisation des résultats de recherches et des innovations au Burkina Faso. Au Burkina Faso, la recherche scientifique et les activités d'invention et d'innovation ont généré de nombreux résultats susceptibles de contribuer au développement endogène. Projet.

  17. Résultats de recherche | Page 110 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Fonds d'innovation pour le développement (FID) aux fins de la recherche en santé mondiale. Le gouvernement du Canada a créé un fonds visant à soutenir la recherche et l'innovation en santé dans le but d'améliorer les conditions de vie des pauvres dans le monde entier. Projet.

  18. Bibliothécaire de recherche (h/f) | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    assurer des services de recherche documentaire complets qui ajoutent à la valeur stratégique des travaux des usagers. L'assistance aux services de recherche spécialisée, la préparation et l'établissement des orientations, la formation et ...

  19. Résultats de recherche | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    26 mars 2018 ... Le programme conjoint canado-israélien de recherche en santé est un programme d'une durée de sept années et d'un budget de 35 millions de CAD, conclu entre le CRDI, l'Israel Science Foundation, l'Azrieli Foundation et les Instituts de recherche en s. Livres.

  20. Résultats de recherche | Page 42 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    C'est inhabituel d'entendre une avocate dire que « la loi n'est pas suffisante en soi. » C'est la conclusion à laquelle est arrivée Gloria Song, titulaire d'une bourse de recherche en 2016, dans le cadre de sa recherche sur la façon dont la Guyane. IDRC awardees ...

  1. Résultats de recherche | Page 47 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Promotion de la recherche de développement : les orientations stratégiques du CRDI. Published date. 1 janvier 2006. Études. -. Usage et état de la recherche sur les TICE au Maroc : état des lieux et perspectives. Published date. 1 janvier 2006. Études.

  2. Histone h1 depletion impairs embryonic stem cell differentiation.

    Science.gov (United States)

    Zhang, Yunzhe; Cooke, Marissa; Panjwani, Shiraj; Cao, Kaixiang; Krauth, Beth; Ho, Po-Yi; Medrzycki, Magdalena; Berhe, Dawit T; Pan, Chenyi; McDevitt, Todd C; Fan, Yuhong

    2012-01-01

    Pluripotent embryonic stem cells (ESCs) are known to possess a relatively open chromatin structure; yet, despite efforts to characterize the chromatin signatures of ESCs, the role of chromatin compaction in stem cell fate and function remains elusive. Linker histone H1 is important for higher-order chromatin folding and is essential for mammalian embryogenesis. To investigate the role of H1 and chromatin compaction in stem cell pluripotency and differentiation, we examine the differentiation of embryonic stem cells that are depleted of multiple H1 subtypes. H1c/H1d/H1e triple null ESCs are more resistant to spontaneous differentiation in adherent monolayer culture upon removal of leukemia inhibitory factor. Similarly, the majority of the triple-H1 null embryoid bodies (EBs) lack morphological structures representing the three germ layers and retain gene expression signatures characteristic of undifferentiated ESCs. Furthermore, upon neural differentiation of EBs, triple-H1 null cell cultures are deficient in neurite outgrowth and lack efficient activation of neural markers. Finally, we discover that triple-H1 null embryos and EBs fail to fully repress the expression of the pluripotency genes in comparison with wild-type controls and that H1 depletion impairs DNA methylation and changes of histone marks at promoter regions necessary for efficiently silencing pluripotency gene Oct4 during stem cell differentiation and embryogenesis. In summary, we demonstrate that H1 plays a critical role in pluripotent stem cell differentiation, and our results suggest that H1 and chromatin compaction may mediate pluripotent stem cell differentiation through epigenetic repression of the pluripotency genes.

  3. Cancer Research UK | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cancer Research UK. https://www.cancerresearchuk.org/. Initiative de recherche sur la dimension économique de la lutte antitabac. L'Initiative de recherche sur la dimension économique de la lutte antitabac finance la recherche novatrice sur les politiques fiscales qui appuient la lutte antitabac dans les pays à faible revenu ...

  4. 1918 pandemic H1N1 DNA vaccine protects ferrets against 2007 H1N1 virus infection

    DEFF Research Database (Denmark)

    Bragstad, Karoline; Martel, Cyril Jean-Marie; Aasted, Bent

    of the H1N1 pandemic virus from 1918 induce protection in ferrets against infection with a H1N1 (A/New Caledonia/20/99(H1N1)) virus which was included in the conventional vaccine for the 2006-2007 season. The viruses are separated by a time interval of 89 years and differ by 21.2% in the HA1 protein...

  5. Radiation detectors

    International Nuclear Information System (INIS)

    2013-01-01

    This sixth chapter presents the operational principles of the radiation detectors; detection using photographic emulsions; thermoluminescent detectors; gas detectors; scintillation detectors; liquid scintillation detectors; detectors using semiconductor materials; calibration of detectors; Bragg-Gray theory; measurement chain and uncertainties associated to measurements

  6. Histone HIST1H1C/H1.2 regulates autophagy in the development of diabetic retinopathy.

    Science.gov (United States)

    Wang, Wenjun; Wang, Qing; Wan, Danyang; Sun, Yue; Wang, Lin; Chen, Hong; Liu, Chengyu; Petersen, Robert B; Li, Jianshuang; Xue, Weili; Zheng, Ling; Huang, Kun

    2017-05-04

    Autophagy plays critical and complex roles in many human diseases, including diabetes and its complications. However, the role of autophagy in the development of diabetic retinopathy remains uncertain. Core histone modifications have been reported involved in the development of diabetic retinopathy, but little is known about the histone variants. Here, we observed increased autophagy and histone HIST1H1C/H1.2, an important variant of the linker histone H1, in the retinas of type 1 diabetic rodents. Overexpression of histone HIST1H1C upregulates SIRT1 and HDAC1 to maintain the deacetylation status of H4K16, leads to upregulation of ATG proteins, then promotes autophagy in cultured retinal cell line. Histone HIST1H1C overexpression also promotes inflammation and cell toxicity in vitro. Knockdown of histone HIST1H1C reduces both the basal and stresses (including high glucose)-induced autophagy, and inhibits high glucose induced inflammation and cell toxicity. Importantly, AAV-mediated histone HIST1H1C overexpression in the retinas leads to increased autophagy, inflammation, glial activation and neuron loss, similar to the pathological changes identified in the early stage of diabetic retinopathy. Furthermore, knockdown of histone Hist1h1c by siRNA in the retinas of diabetic mice significantly attenuated the diabetes-induced autophagy, inflammation, glial activation and neuron loss. These results indicate that histone HIST1H1C may offer a novel therapeutic target for preventing diabetic retinopathy.

  7. Regulation of Cellular Dynamics and Chromosomal Binding Site Preference of Linker Histones H1.0 and H1.X.

    Science.gov (United States)

    Okuwaki, Mitsuru; Abe, Mayumi; Hisaoka, Miharu; Nagata, Kyosuke

    2016-11-01

    Linker histones play important roles in the genomic organization of mammalian cells. Of the linker histone variants, H1.X shows the most dynamic behavior in the nucleus. Recent research has suggested that the linker histone variants H1.X and H1.0 have different chromosomal binding site preferences. However, it remains unclear how the dynamics and binding site preferences of linker histones are determined. Here, we biochemically demonstrated that the DNA/nucleosome and histone chaperone binding activities of H1.X are significantly lower than those of other linker histones. This explains why H1.X moves more rapidly than other linker histones in vivo Domain swapping between H1.0 and H1.X suggests that the globular domain (GD) and C-terminal domain (CTD) of H1.X independently contribute to the dynamic behavior of H1.X. Our results also suggest that the N-terminal domain (NTD), GD, and CTD cooperatively determine the preferential binding sites, and the contribution of each domain for this determination is different depending on the target genes. We also found that linker histones accumulate in the nucleoli when the nucleosome binding activities of the GDs are weak. Our results contribute to understanding the molecular mechanisms of dynamic behaviors, binding site selection, and localization of linker histones. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  8. Epidemiological characteristics of Pandemic Influenza A (H1N1 ...

    African Journals Online (AJOL)

    Background: A novel influenza A virus strain (H1N1-2009) spread first in Mexico and the United Stated in late April 2009, leading to the first influenza pandemic of the 21st century. The objective of this study was to determine the epidemiological and virological characteristics of the pandemic influenza A (H1N1-2009) in ...

  9. Epidemiological characteristics of Pandemic Influenza A (H1N1 ...

    African Journals Online (AJOL)

    ... novel influenza A virus strain (H1N1-2009) spread first in Mexico and the United Stated in late April 2009, leading to the first influenza pandemic of the 21st century. The objective of this study was to determine the epidemiological and virological characteristics of the pandemic influenza A (H1N1-2009) in Zhanjiang, China ...

  10. (H1N1) Influenza in Saurashtra, India

    African Journals Online (AJOL)

    Mexico in April, 2009,[1] and then in United States (US).[2,3]. This was originally ... duration of hospital stay of such patients was 2‑32 days. All admitted A (H1N1) .... Because of limited resources, only 2009 A (H1N1) influenza virus was tested ...

  11. Histone H1(0) mapping using monoclonal antibodies.

    Science.gov (United States)

    Dousson, S; Gorka, C; Gilly, C; Lawrence, J J

    1989-06-01

    Monoclonal antibodies (mAb) to ox liver histone H1 degree were produced and characterized. Two sets of mice were immunized either with pure H1(0) or with an H1(0)-yeast tRNA complex. Eleven hybridomas of various clonal origin were selected. Typing of the antibodies indicated that all but three IgM belonged to the IgG1 class and contained kappa light chains. Immunoblotting experiments using peptides derived from H1(0) or H5 treated by various proteolytic agents (trypsin, N-bromosuccinimide, cyanogen bromide, acetic acid), revealed that nine of the mAb reacted with the globular part of H1(0). More advanced characterization of the antigenic determinants allowed us to determine distinct regions within this globular part which are involved in the antigenic recognition. The peptopes could be subdivided into two groups. Three mAb bound to residues 24-27 and were specific for H1(0). Six mAb bound to residues 27-30 and were specific for H1(0) except one of them which strongly cross-reacted with H5 and GH5. Two mAb reacted with the entire histone H1(0) but failed to react with any of the peptides, suggesting that the corresponding epitope is a conformational antigenic determinant. In order to confirm the localization of the two distinct regions which are involved in the antigenic recognition, a synthetic decapeptide corresponding to the beginning of human H1(0) globular part (from residue 19 to residue 28) was synthesized. Inhibition experiments of the reaction between H1(0) and the various IgG1 mAb by increasing amounts of peptide-bovine serum albumin conjugates were then performed.

  12. Sensitive and selective magnetoimmunosensing platform for determination of the food allergen Ara h 1

    International Nuclear Information System (INIS)

    Montiel, V. Ruiz-Valdepeñas; Campuzano, S.; Pellicanò, A.; Torrente-Rodríguez, R.M.; Reviejo, A.J.; Cosio, M.S.; Pingarrón, J.M.

    2015-01-01

    Highlights: • First amperometric magnetoimmunosensor for Ara h 1 determination. • Sensitive and selective detection of Ara h 1 in 2 h. • LOD of 6.3 ng mL −1 . • Determinations in food extracts and saliva. • Potential applicability in food safety and consumer protection. - Abstract: A highly sensitive disposable amperometric immunosensor based on the use of magnetic beads (MBs) is described for determination of Ara h 1, the major peanut allergen, in only 2 h. The approach uses a sandwich configuration involving selective capture and biotinylated detector antibodies and carboxylic acid-modified MBs (HOOC-MBs). The MBs bearing the immunoconjugates are captured by a magnet placed under the surface of a disposable screen-printed carbon electrode (SPCE) and the affinity reactions are monitored amperometrically at −0.20 V (vs a Ag pseudo-reference electrode) in the presence of hydroquinone (HQ) as electron transfer mediator and upon addition of H 2 O 2 as the enzyme substrate. The developed immunosensor exhibits a wide range of linearity between 20.8 and 1000.0 ng mL −1 Ara h 1, a detection limit of 6.3 ng mL −1 , a great selectivity, a good reproducibility with a RSD of 6.3% for six different immunosensors and a useful lifetime of 25 days. The usefulness of the immunosensor was demonstrated by determining Ara h 1 in different matrices (food extracts and saliva). The results correlated properly with those provided by a commercial ELISA method offering a reliable and promising analytical screening tool in the development of user-friendly devices for on-site determination of Ara h 1

  13. Sensitive and selective magnetoimmunosensing platform for determination of the food allergen Ara h 1

    Energy Technology Data Exchange (ETDEWEB)

    Montiel, V. Ruiz-Valdepeñas, E-mail: victor_lega90@hotmail.com [Departamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, E-28040 Madrid (Spain); Campuzano, S., E-mail: susanacr@quim.ucm.es [Departamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, E-28040 Madrid (Spain); Pellicanò, A., E-mail: alessandro.pellicano@unimi.it [Department of Food, Environmental and Nutritional Sciences (DEFENS), University of Milan, Via Celoria 2, 20133 Milan (Italy); Torrente-Rodríguez, R.M., E-mail: rebeca.magnolia@gmail.com [Departamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, E-28040 Madrid (Spain); Reviejo, A.J., E-mail: reviejo@quim.ucm.es [Departamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, E-28040 Madrid (Spain); Cosio, M.S., E-mail: stella.cosio@unimi.it [Department of Food, Environmental and Nutritional Sciences (DEFENS), University of Milan, Via Celoria 2, 20133 Milan (Italy); Pingarrón, J.M., E-mail: pingarro@quim.ucm.es [Departamento de Química Analítica, Facultad de CC. Químicas, Universidad Complutense de Madrid, E-28040 Madrid (Spain)

    2015-06-23

    Highlights: • First amperometric magnetoimmunosensor for Ara h 1 determination. • Sensitive and selective detection of Ara h 1 in 2 h. • LOD of 6.3 ng mL{sup −1}. • Determinations in food extracts and saliva. • Potential applicability in food safety and consumer protection. - Abstract: A highly sensitive disposable amperometric immunosensor based on the use of magnetic beads (MBs) is described for determination of Ara h 1, the major peanut allergen, in only 2 h. The approach uses a sandwich configuration involving selective capture and biotinylated detector antibodies and carboxylic acid-modified MBs (HOOC-MBs). The MBs bearing the immunoconjugates are captured by a magnet placed under the surface of a disposable screen-printed carbon electrode (SPCE) and the affinity reactions are monitored amperometrically at −0.20 V (vs a Ag pseudo-reference electrode) in the presence of hydroquinone (HQ) as electron transfer mediator and upon addition of H{sub 2}O{sub 2} as the enzyme substrate. The developed immunosensor exhibits a wide range of linearity between 20.8 and 1000.0 ng mL{sup −1} Ara h 1, a detection limit of 6.3 ng mL{sup −1}, a great selectivity, a good reproducibility with a RSD of 6.3% for six different immunosensors and a useful lifetime of 25 days. The usefulness of the immunosensor was demonstrated by determining Ara h 1 in different matrices (food extracts and saliva). The results correlated properly with those provided by a commercial ELISA method offering a reliable and promising analytical screening tool in the development of user-friendly devices for on-site determination of Ara h 1.

  14. Reassortant H1N1 influenza virus vaccines protect pigs against pandemic H1N1 influenza virus and H1N2 swine influenza virus challenge.

    Science.gov (United States)

    Yang, Huanliang; Chen, Yan; Shi, Jianzhong; Guo, Jing; Xin, Xiaoguang; Zhang, Jian; Wang, Dayan; Shu, Yuelong; Qiao, Chuanling; Chen, Hualan

    2011-09-28

    Influenza A (H1N1) virus has caused human influenza outbreaks in a worldwide pandemic since April 2009. Pigs have been found to be susceptible to this influenza virus under experimental and natural conditions, raising concern about their potential role in the pandemic spread of the virus. In this study, we generated a high-growth reassortant virus (SC/PR8) that contains the hemagglutinin (HA) and neuraminidase (NA) genes from a novel H1N1 isolate, A/Sichuan/1/2009 (SC/09), and six internal genes from A/Puerto Rico/8/34 (PR8) virus, by genetic reassortment. The immunogenicity and protective efficacy of this reassortant virus were evaluated at different doses in a challenge model using a homologous SC/09 or heterologous A/Swine/Guangdong/1/06(H1N2) virus (GD/06). Two doses of SC/PR8 virus vaccine elicited high-titer serum hemagglutination inhibiting (HI) antibodies specific for the 2009 H1N1 virus and conferred complete protection against challenge with either SC/09 or GD/06 virus, with reduced lung lesions and viral shedding in vaccine-inoculated animals compared with non-vaccinated control animals. These results indicated for the first time that a high-growth SC/PR8 reassortant H1N1 virus exhibits properties that are desirable to be a promising vaccine candidate for use in swine in the event of a pandemic H1N1 influenza. Copyright © 2011 Elsevier B.V. All rights reserved.

  15. Commissioning of the SPACAL calorimeter of H1 and analysis of large transverse energy processes

    International Nuclear Information System (INIS)

    Zini, P.

    1998-01-01

    The lepton-nucleon scattering experiments take a prominent part in the matter structure study. The H1 experiment (HERA), progressed regularly and the accumulated luminosity allows today the exploration of the phase space limits to the high energies. The H1 detector has been improved: SPACAL the new calorimeter since 1995 is the main part. This thesis presents two parts. The first one deals with the calorimeter performances study, the second one with the events of very high transverse energy. The most depopulated area of the phase space are explored. For these regions it was necessary to improve the theoretical forecasting; analytical calculations have been used. These studies on the extreme processes understanding will be very useful for the high luminosity period of HERA, between 2000 and 2005. This study is a solid base for the researches on new phenomena leading to the existence of a physics upper the standard model. (A.L.B.)

  16. Shower library technique for fast simulation of showers in calorimeters of the H1 experiment

    International Nuclear Information System (INIS)

    Raičević, N.; Glazov, A.; Zhokin, A.

    2013-01-01

    Fast simulation of showers in calorimeters is very important for particle physics analysis since shower simulation typically takes significant amount of the simulation time. At the same time, a simulation must reproduce experimental data in the best possible way. In this paper, a fast simulation of showers in two calorimeters of the H1 experiment is presented. High speed and good quality of shower simulation is achieved by using a shower library technique in which the detector response is simulated using a collection of stored showers for different particle types and topologies. The library is created using the GEANT programme. The fast simulation based on shower library is compared to the data collected by the H1 experiment

  17. 77 FR 3284 - Comment Request for Information Collection for the H-1B Technical Skills Training (H-1B) and the...

    Science.gov (United States)

    2012-01-23

    ... concerning the collection of data about H-1B Technical Skills Training (H-1B) [SGA/DFA PY-10-13] and H-1B... DEPARTMENT OF LABOR Comment Request for Information Collection for the H-1B Technical Skills Training (H-1B) and the H-1B Jobs and Innovation Accelerator Challenge (JIAC) Grant Programs, New...

  18. Influenza A (H1N1) organising pneumonia.

    Science.gov (United States)

    Torrego, Alfons; Pajares, Virginia; Mola, Anna; Lerma, Enrique; Franquet, Tomás

    2010-04-27

    In November 2009, countries around the world reported confirmed cases of pandemic influenza H1N1, including over 6000 deaths. No peak in activity has been seen. The most common causes of death are pneumonia and acute respiratory distress syndrome. We report a case of a 55-year-old woman who presented with organising pneumonia associated with influenza A (H1N1) infection confirmed by transbronchial lung biopsy. Organising pneumonia should also be considered as a possible complication of influenza A (H1N1) infection, given that these patients can benefit from early diagnosis and appropriate specific management.

  19. Novel 1H-1,2,3-, 2H-1,2,3-, 1H-1,2,4- and 4H-1,2,4-triazole derivatives: a patent review (2008 - 2011).

    Science.gov (United States)

    Ferreira, Vitor F; da Rocha, David R; da Silva, Fernando C; Ferreira, Patrícia G; Boechat, Núbia A; Magalhães, Jorge L

    2013-03-01

    The triazoles represent a class of five-membered heterocyclic compounds of great importance for the preparation of new drugs with diverse biological activities because they may present several structural variations with the same numbers of carbon and nitrogen atoms. Due to the success of various triazoles that entered the pharmaceutical market and are still being used in medicines, many companies and research groups have shown interest in developing new methods of synthesis and biological evaluation of potential uses for these compounds. In this review, the authors explored aspects of patents for the 1H-1,2,3-, 2H-1,2,3-, 1H-1,2,4- and 4H-1,2,4-triazole families, including prototypes being considered in clinical studies between 2008 and 2011. The triazoles have been studied for over a century as an important class of heterocyclic compounds and still attract considerable attention due to their broad range of biological activities. More recently, there has been considerable interest in the development of novel triazoles with anti-inflammatory, antiplatelet, antimicrobial, antimycobacterial, antitumoral and antiviral properties and activity against several neglected diseases. This review emphasizes recent perspective and advances in the therapeutically active 1H-1,2,3-, 2H-1,2,3-, 1H-1,2,4- and 4H-1,2,4-triazole derivative patents between 2008 and 2011, covering the development of new chemical entities and new pharmaceuticals. Many studies have focused on these compounds as target structures and evaluated them in several biological targets. The preparation of 1H-1,2,3-, 2H-1,2,3-, 1H-1,2,4- and 4H-1,2,4-triazole derivatives brings to light several issues. There is a need to find new, more efficient preparations for these triazoles that take into consideration current issues in green chemistry, energy saving and sustainability. New diseases are discovered and new viruses and bacteria continue to challenge mankind, so it is imperative to find new prototypes for these

  20. Résultats de recherche | Page 2 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    entrepreneuriat à Madagascar. Le projet vise à promouvoir l'entrepreneuriat des femmes et des jeunes à Madagascar à travers le renforcement des capacités locales de recherche et des analyses pertinentes et utiles. Projet ...

  1. Production, purification, crystallization and structure determination of H-1 Parvovirus

    International Nuclear Information System (INIS)

    Halder, Sujata; Nam, Hyun-Joo; Govindasamy, Lakshmanan; Vogel, Michèle; Dinsart, Christiane; Salomé, Nathalie; McKenna, Robert; Agbandje-McKenna, Mavis

    2012-01-01

    The production, purification, crystallization and crystallographic analysis of H-1 Parvovirus, a gene-therapy vector, are reported. Crystals of H-1 Parvovirus (H-1PV), an antitumor gene-delivery vector, were obtained for DNA-containing capsids and diffracted X-rays to 2.7 Å resolution using synchrotron radiation. The crystals belonged to the monoclinic space group P2 1 , with unit-cell parameters a = 255.4, b = 350.4, c = 271.6 Å, β = 90.34°. The unit cell contained two capsids, with one capsid per crystallographic asymmetric unit. The H-1PV structure has been determined by molecular replacement and is currently being refined

  2. H-1NF: Australian national fusion plasma research facility

    International Nuclear Information System (INIS)

    Blackwell, B.D.; Borg, G.G.; Dewar, R.L.; Howard, J.; Gardner, H.J.; Rudakov, D.L.; Sharp, L.E.; Shats, M.G.; Warr, G.B.

    1997-01-01

    The H-1 heliac is a helical axis stellarator of moderate size and novel, flexible configuration. Since commissioning, H-1 has operated in quasi-continuous mode at low magnetic field. For higher fields ≤1T an ECRH heating system (28GHz, 200kW) has been installed under a collaborative agreement between ANU and NIFS. H-1 has recently been promoted to national facility status (H-1NF), which will include upgrades of the rf and ech heating systems to megawatt powers, and power supply and diagnostic and data system enhancements. This facilitates collaborative research locally (through the Australian Fusion Research Group consortium) and internationally. Results of a number of basic experiments in quasi-continuous mode are presented. (author)

  3. Teledyne H1RG, H2RG, and H4RG Noise Generator

    Science.gov (United States)

    Rauscher, Bernard J.

    2015-01-01

    This paper describes the near-infrared detector system noise generator (NG) that we wrote for the James Webb Space Telescope (JWST) Near Infrared Spectrograph (NIRSpec). NG simulates many important noise components including; (1) white "read noise", (2) residual bias drifts, (3) pink 1/f noise, (4) alternating column noise, and (5) picture frame noise. By adjusting the input parameters, NG can simulate noise for Teledyne's H1RG, H2RG, and H4RG detectors with and without Teledyne's SIDECAR ASIC IR array controller. NG can be used as a starting point for simulating astronomical scenes by adding dark current, scattered light, and astronomical sources into the results from NG. NG is written in Python-3.4.

  4. Early Detection of Pandemic (H1N1) 2009, Bangladesh

    Science.gov (United States)

    Rahman, Mustafizur; Al Mamun, Abdullah; Haider, Mohammad Sabbir; Zaman, Rashid Uz; Karmakar, Polash Chandra; Nasreen, Sharifa; Muneer, Syeda Mah-E; Homaira, Nusrat; Goswami, Doli Rani; Ahmed, Be-Nazir; Husain, Mohammad Mushtuq; Jamil, Khondokar Mahbuba; Khatun, Selina; Ahmed, Mujaddeed; Chakraborty, Apurba; Fry, Alicia; Widdowson, Marc-Alain; Bresee, Joseph; Azim, Tasnim; Alamgir, A.S.M.; Brooks, Abdullah; Hossain, Mohamed Jahangir; Klimov, Alexander; Rahman, Mahmudur; Luby, Stephen P.

    2012-01-01

    To explore Bangladesh’s ability to detect novel influenza, we examined a series of laboratory-confirmed pandemic (H1N1) 2009 cases. During June–July 2009, event-based surveillance identified 30 case-patients (57% travelers); starting July 29, sentinel sites identified 252 case-patients (1% travelers). Surveillance facilitated response weeks before the spread of pandemic (H1N1) 2009 infection to the general population. PMID:22257637

  5. Measurement of electric fields in the H-1NF heliac

    International Nuclear Information System (INIS)

    James, B.W.; Howard, J.

    1999-01-01

    There are a number of laser induced fluorescence techniques which can be used to measure internal plasma electric fields. It is planned to use a technique based on Stark mixing of energy levels in a supersonic beam containing metastable helium atoms to measure radial electric fields in H-1NF. Enhanced values of radial electric field are associated with improved confinement modes in H-1NF and other magnetically confined plasmas

  6. Résultats de recherche | Page 16 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Des résultats de recherche mènent à la réalisation d'essais de prévention du VIH dans l'ensemble du Botswana. Un nouveau projet de recherche sur la prévention du VIH a conduit à la réalisation d'un essai national novateur de prévention du VIH au Botswana. En vedette. Health CAUSE OF DEATH MATERNAL AND ...

  7. Bourse de recherche — Comité consultatif d'éthique de la recherche ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    7 sept. 2016 ... À l'occasion, le titulaire de la bourse de recherche offrira également du soutien au programme d'accueil, Fondements pour l'innovation, avec la gestion du programme. En l'occurrence, ces activités comprendront : Coordonner des séminaires et des événements de formation sur l'éthique de la recherche ...

  8. Résultats de recherche | Page 122 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Améliorer l'intégration des jeunes chercheurs africains dans les systèmes de recherche et d'innovation. Les crises économiques vécues par les pays africains depuis la fin des années 1970 ainsi que les programmes d'ajustement structurel qui les suivaient ont relégué la recherche scientifique et l'innovation technologique ...

  9. Résultats de recherche | Page 51 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Soutien organisationnel de la phase 2 de l'ITT : Grupo FARO. Ce financement contribuera à renforcer le rôle du Grupo FARO en tant qu'organisme crédible de recherche sur les politiques publiques en Équateur en renforçant sa capacité à fournir des recherches de qualité supérieure, influentes et utiles en mati. Projet.

  10. Résultats de recherche | Page 44 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    31 juil. 2017 ... Freiner le penchant pour les sucreries des enfants bangladais. Si l'on se fie à la recherche de Parnali Chowdury, les enfants bangladais n'abandonneront pas leurs boissons sucrées facilement. ... Le rôle de la recherche dans la mise en œuvre de la Politique d'aide internationale féministe du Canada.

  11. Résultats de recherche | Page 2 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ce financement contribuera à renforcer le rôle du Public Affairs Centre (PAC) en tant qu'organisme crédible de recherche sur les politiques publiques en Inde en renforçant sa capacité à fournir des recherches de qualité ... Soutien organisationnel pour la phase 2 de l'ITT : Centre for Budget and Governance Accountability.

  12. Résultats de recherche | Page 17 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Des résultats de recherche mènent à la réalisation d'essais de prévention du VIH dans l'ensemble du Botswana. Un nouveau projet de recherche sur la prévention du VIH a conduit à la réalisation d'un essai national novateur de prévention du VIH au Botswana. En vedette. Health CAUSE OF DEATH MATERNAL AND ...

  13. Résultats de recherche | Page 356 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Selon Edgard Rodriguez, spécialiste de programme principal au CRDI, la recherche sur les NTA est importante parce qu'elle aide les gouvernements à pondérer leur soutien en fonction des besoins des différents ... La recherche sur la criminalité chez les jeunes fait ressortir la nécessité d'investir dans le capital social.

  14. Résultats de recherche | Page 440 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Savoir, innovation, solutions: septième assemblée publique annuelle du CRDI. « Le CRDI a toujours recherché les résultats concrets, car les recherches que nous finançons sont trop importantes pour rester lettre morte, a ajouté le président par intérim à l'assemblée ayant eu lieu à Ottawa le 17 novembre 2015. Date de ...

  15. Résultats de recherche | Page 92 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ce financement contribuera à renforcer le rôle de l'Asociación de Investigación y Estudios Sociales (ASIES) en tant qu'organisme crédible de recherche sur les ... le programme de renforcement des capacités pour des essais en matière de prévention du VIH/sida en Afrique sous l'égide de l'Initiative de recherche en santé ...

  16. Résultats de recherche | Page 43 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    J'ai quitté Ottawa en aspirant à cerner les besoins des mères au Népal et à découvrir des façons d'offrir de meilleurs soins de santé », explique Sunisha Neupane, titulaire d'une bourse de recherche en 2015. IDRC awardees. Renforcer les possibilités de collaboration en recherche avec la Chine. L'essor économique de la ...

  17. Fusion plasma physics research on the H-1 national facility

    International Nuclear Information System (INIS)

    Harris, J.

    1998-01-01

    Full text: Australia has a highly leveraged fusion plasma research program centred on the H-1 National Facility device at the ANU. H-1 is a heliac, a novel helical axis stellarator that was experimentally pioneered in Australia, but has a close correlation with the worldwide research program on toroidal confinement of fusion grade plasma. Experiments are conducted on H-1 by university researchers from the Australian Fusion Research Group (comprising groups from the ANU, the Universities of Sydney, Western Sydney, Canberra, New England, and Central Queensland University) under the aegis of AINSE; the scientists also collaborate with fusion researchers from Japan and the US. Recent experiments on H-1 have focused on improved confinement modes that can be accessed at very low powers in H-1, but allow the study of fundamental physics effects seen on much larger machines at higher powers. H-1 is now being upgraded in magnetic field and heating power, and will be able to confine hotter plasmas beginning in 1999, offering greatly enhanced research opportunities for Australian plasma scientists and engineers, with substantial spillover of ideas from fusion research into other areas of applied physics and engineering

  18. Germline-specific H1 variants: the "sexy" linker histones.

    Science.gov (United States)

    Pérez-Montero, Salvador; Carbonell, Albert; Azorín, Fernando

    2016-03-01

    The eukaryotic genome is packed into chromatin, a nucleoprotein complex mainly formed by the interaction of DNA with the abundant basic histone proteins. The fundamental structural and functional subunit of chromatin is the nucleosome core particle, which is composed by 146 bp of DNA wrapped around an octameric protein complex formed by two copies of each core histone H2A, H2B, H3, and H4. In addition, although not an intrinsic component of the nucleosome core particle, linker histone H1 directly interacts with it in a monomeric form. Histone H1 binds nucleosomes near the exit/entry sites of linker DNA, determines nucleosome repeat length and stabilizes higher-order organization of nucleosomes into the ∼30 nm chromatin fiber. In comparison to core histones, histone H1 is less well conserved through evolution. Furthermore, histone H1 composition in metazoans is generally complex with most species containing multiple variants that play redundant as well as specific functions. In this regard, a characteristic feature is the presence of specific H1 variants that replace somatic H1s in the germline and during early embryogenesis. In this review, we summarize our current knowledge about their structural and functional properties.

  19. Molecular treatment of the ion-pair formation reaction in H(1s) + H(1s) collisions

    International Nuclear Information System (INIS)

    Borondo, F.; Martin, F.; Yaez, M.

    1987-01-01

    All the available theoretical calculations of the cross section for the ion-pair formation reaction H(1s)+H(1s)→H + H - (1s 2 ) have been performed using methods that are only valid at high collision energies. They get good agreement with the experiments for impact energies greater than 25 keV, but fail completely at smaller energies. In this work we report the cross section for this reaction at impact energies less than 10 keV, calculated in the framework of the impact-parameter approximation and using the molecular method with a common translation factor

  20. Search for low energy quasi-vertical muons with an underwater cosmic neutrino detector, environmental study of the detector setting; Recherche de muons quasi verticaux de basse energie a l'aide d'un detecteur de neutrinos cosmiques sous-marin et etude environnementale de son site d'installation

    Energy Technology Data Exchange (ETDEWEB)

    Blondeau, F. [CEA/Saclay, Dept. d' Astrophysique, de la Physique des Particules, de la Physique Nucleaire et de l' Instrumentation Associee (DAPNIA), 91 - Gif-sur-Yvette (France)]|[Paris-7 Univ., 75 (France)

    1999-06-01

    The European collaboration named ANTARES aims at operating a large submarine neutrino telescope. Mooring lines make up this detector. Each is about four hundred metres high and equipped with photomultiplier tubes. These tubes record the Cherenkov light emitted by muons resulting from the interaction of neutrinos with matter. It was chosen to install the telescope in the Mediterranean, off the shore of Toulon, by a depth of twenty-three hundred metres. One chapter of this dissertation is devoted to the environment parameters of this site: amount of natural light, fouling of glass elements and water transparency is reviewed. Such a disposal is originally designed to look for possible astronomic neutrino sources emitting neutrinos, thus being complementary with the study of our Universe relying on gamma rays. It is shown in this dissertation that two other current riddles in physics can be investigated by ANTARES, when a specific analysis is taken into account: what is the mass of the neutrinos on the one hand (via the phenomenon called neutrino oscillations), and in the other hand the evidence for a new particle which could participate to the nature of the dark matter in the Universe. This analysis is based upon the detection of nearly vertical muons (zenith angle less than fifteen degrees), with an energy lower than 100 GeV. (author)

  1. Study and testing of the photomultipliers of TILECAL calorimeter of ATLAS detector. Search for stop t-tilde{sub 1} with ATLAS detector; Etude et caracterisation des photomultiplicateurs du calorimetre a tuiles scintillantes d'atlas. Recherche du stop t-tilde{sub 1} avec le detecteur atlas

    Energy Technology Data Exchange (ETDEWEB)

    Hebrard, Ch

    1999-11-04

    The first part of this thesis presents the prospective study on the possibility that we observe an excess of event with four light quark jets, two b quark jets and missing transverse energy in comparison with the predictions of standard model. In the frame of the SUperGRAvity (SUGRA) these events are produced by the Stop decay. The results show that it will be possible to observe an excess of events if Stop mass is less than 600 GeV. The second part of this work turns on the design of the photomultipliers which will be used in ATLAS Tile Calorimeter. A huge work of development and optimisation has been done to make R7877 Hamamatsu photomultiplier fitting all the specifications dictating by the detector. The measurements developed to characterize the photomultipliers are discussed. An special effort has been done to understand and solve the problem of instability of R7877 photomultiplier. In the future, Tile calorimeter will be equipped with 10000 photomultipliers, so a test bench has been developed in order to characterize all these photomultipliers. The performances of this test bench are inspected for each type of measurement (amplification, quantum efficiency, collection efficiency, dark current, linearity and stability). The specifications and technical design of this test bench are summarized in annexes. (author)

  2. Search for low energy quasi-vertical muons with an underwater cosmic neutrino detector, environmental study of the detector setting; Recherche de muons quasi verticaux de basse energie a l'aide d'un detecteur de neutrinos cosmiques sous-marin et etude environnementale de son site d'installation

    Energy Technology Data Exchange (ETDEWEB)

    Blondeau, F [CEA/Saclay, Dept. d' Astrophysique, de la Physique des Particules, de la Physique Nucleaire et de l' Instrumentation Associee (DAPNIA), 91 - Gif-sur-Yvette (France); [Paris-7 Univ., 75 (France)

    1999-06-01

    The European collaboration named ANTARES aims at operating a large submarine neutrino telescope. Mooring lines make up this detector. Each is about four hundred metres high and equipped with photomultiplier tubes. These tubes record the Cherenkov light emitted by muons resulting from the interaction of neutrinos with matter. It was chosen to install the telescope in the Mediterranean, off the shore of Toulon, by a depth of twenty-three hundred metres. One chapter of this dissertation is devoted to the environment parameters of this site: amount of natural light, fouling of glass elements and water transparency is reviewed. Such a disposal is originally designed to look for possible astronomic neutrino sources emitting neutrinos, thus being complementary with the study of our Universe relying on gamma rays. It is shown in this dissertation that two other current riddles in physics can be investigated by ANTARES, when a specific analysis is taken into account: what is the mass of the neutrinos on the one hand (via the phenomenon called neutrino oscillations), and in the other hand the evidence for a new particle which could participate to the nature of the dark matter in the Universe. This analysis is based upon the detection of nearly vertical muons (zenith angle less than fifteen degrees), with an energy lower than 100 GeV. (author)

  3. Penser localement, agir globalement : Comment la recherche ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    13 avr. 2018 ... Les Prix Canada Gairdner reconnaissent les scientifiques du domaine biomédical les plus créatifs et accomplis du monde qui font progresser l'humanité et le monde. Joignez-vous au Dr Cesar Victora pour une discussion intéressante sur les liens entre la recherche locale et les politiques mondiales.

  4. Ion chemistry of 1H-1,2,3-triazole.

    Science.gov (United States)

    Ichino, Takatoshi; Andrews, Django H; Rathbone, G Jeffery; Misaizu, Fuminori; Calvi, Ryan M D; Wren, Scott W; Kato, Shuji; Bierbaum, Veronica M; Lineberger, W Carl

    2008-01-17

    A combination of experimental methods, photoelectron-imaging spectroscopy, flowing afterglow-photoelectron spectroscopy and the flowing afterglow-selected ion flow tube technique, and electronic structure calculations at the B3LYP/6-311++G(d,p) level of density functional theory (DFT) have been employed to study the mechanism of the reaction of the hydroxide ion (HO-) with 1H-1,2,3-triazole. Four different product ion species have been identified experimentally, and the DFT calculations suggest that deprotonation by HO- at all sites of the triazole takes place to yield these products. Deprotonation of 1H-1,2,3-triazole at the N1-H site gives the major product ion, the 1,2,3-triazolide ion. The 335 nm photoelectron-imaging spectrum of the ion has been measured. The electron affinity (EA) of the 1,2,3-triazolyl radical has been determined to be 3.447 +/- 0.004 eV. This EA and the gas-phase acidity of 2H-1,2,3-triazole are combined in a negative ion thermochemical cycle to determine the N-H bond dissociation energy of 2H-1,2,3-triazole to be 112.2 +/- 0.6 kcal mol-1. The 363.8 nm photoelectron spectroscopic measurements have identified the other three product ions. Deprotonation of 1H-1,2,3-triazole at the C5 position initiates fragmentation of the ring structure to yield a minor product, the ketenimine anion. Another minor product, the iminodiazomethyl anion, is generated by deprotonation of 1H-1,2,3-triazole at the C4 position, followed by N1-N2 bond fission. Formation of the other minor product, the 2H-1,2,3-triazol-4-ide ion, can be rationalized by initial deprotonation of 1H-1,2,3-triazole at the N1-H site and subsequent proton exchanges within the ion-molecule complex. The EA of the 2H-1,2,3-triazol-4-yl radical is 1.865 +/- 0.004 eV.

  5. Ionization detector

    International Nuclear Information System (INIS)

    Steele, D.S.

    1987-01-01

    An ionization detector having an array of detectors has, for example, grounding pads positioned in the spaces between some detectors (data detectors) and other detectors (reference detectors). The grounding pads are kept at zero electric potential, i.e. grounded. The grounding serves to drain away electrons and thereby prevent an unwanted accumulation of charge in the spaces, and cause the electric field lines to be more perpendicular to the detectors in regions near the grounding pads. Alternatively, no empty space is provided there being additional, grounded, detectors provided between the data and reference detectors. (author)

  6. H1N1, globalization and the epidemiology of inequality.

    Science.gov (United States)

    Sparke, Matthew; Anguelov, Dimitar

    2012-07-01

    This paper examines the lessons learned from the 2009 H1N1 pandemic in relation to wider work on globalization and the epidemiology of inequality. The media attention and economic resources diverted to the threats posed by H1N1 were significant inequalities themselves when contrasted with weaker responses to more lethal threats posed by other diseases associated with global inequality. However, the multiple inequalities revealed by H1N1 itself in 2009 still provide important insights into the future of global health in the context of market-led globalization. These lessons relate to at least four main forms of inequality: (1) inequalities in blame for the outbreak in the media; (2) inequalities in risk management; (3) inequalities in access to medicines; and (4) inequalities encoded in the actual emergence of new flu viruses. Copyright © 2011 Elsevier Ltd. All rights reserved.

  7. Characteristics of the mouse genomic histamine H1 receptor gene

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, Isao; Taniuchi, Ichiro; Kitamura, Daisuke [Kyushu Univ., Fukuoka (Japan)] [and others

    1996-08-15

    We report here the molecular cloning of a mouse histamine H1 receptor gene. The protein deduced from the nucleotide sequence is composed of 488 amino acid residues with characteristic properties of GTP binding protein-coupled receptors. Our results suggest that the mouse histamine H1 receptor gene is a single locus, and no related sequences were detected. Interspecific backcross analysis indicated that the mouse histamine H1 receptor gene (Hrh1) is located in the central region of mouse Chromosome 6 linked to microphthalmia (Mitfmi), ras-related fibrosarcoma oncogene 1 (Raf1), and ret proto-oncogene (Ret) in a region of homology with human chromosome 3p. 12 refs., 3 figs.

  8. Treatment and Prevention of Pandemic H1N1 Influenza.

    Science.gov (United States)

    Rewar, Suresh; Mirdha, Dashrath; Rewar, Prahlad

    2015-01-01

    Swine influenza is a respiratory infection common to pigs worldwide caused by type A influenza viruses, principally subtypes H1N1, H1N2, H2N1, H3N1, H3N2, and H2N3. Swine influenza viruses also can cause moderate to severe illness in humans and affect persons of all age groups. People in close contact with swine are at especially high risk. Until recently, epidemiological study of influenza was limited to resource-rich countries. The World Health Organization declared an H1N1 pandemic on June 11, 2009, after more than 70 countries reported 30,000 cases of H1N1 infection. In 2015, incidence of swine influenza increased substantially to reach a 5-year high. In India in 2015, 10,000 cases of swine influenza were reported with 774 deaths. The Centers for Disease Control and Prevention recommend real-time polymerase chain reaction as the method of choice for diagnosing H1N1. Antiviral drugs are the mainstay of clinical treatment of swine influenza and can make the illness milder and enable the patient to feel better faster. Antiviral drugs are most effective when they are started within the first 48 hours after the clinical signs begin, although they also may be used in severe or high-risk cases first seen after this time. The Centers for Disease Control and Prevention recommends use of oseltamivir (Tamiflu, Genentech) or zanamivir (Relenza, GlaxoSmithKline). Prevention of swine influenza has 3 components: prevention in swine, prevention of transmission to humans, and prevention of its spread among humans. Because of limited treatment options, high risk for secondary infection, and frequent need for intensive care of individuals with H1N1 pneumonia, environmental control, including vaccination of high-risk populations and public education are critical to control of swine influenza out breaks. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  9. Lower and upper chromatic numbers for BSTSs(2h - 1

    Directory of Open Access Journals (Sweden)

    Marco Buratti

    2001-08-01

    Full Text Available In [Discrete Math. 174, (1997 247-259] an infinite class of STSs(2h - 1 was found with the upper chromatic number not(χ=h. We prove that in this class, for all STSs(2h - 1 with h<10, the lower chromatic number coincides with the upper chromatic number, i.e. χ=not(χ=h and moreover, there exists a infinite sub-class of STSs with χ=not(χ=h for any value of h.

  10. Narcolepsy: Association with H1N1 Infection and Vaccination

    Directory of Open Access Journals (Sweden)

    Ji Hyun Song

    2016-12-01

    Full Text Available Epidemiological studies have demonstrated an association between H1N1 influenza infection and vaccinations. This article reviews the various studies, and suggests the biological mechanisms explaining why and how H1N1 influenza infection or vaccine stimulates the autoimmune response, thereby resulting in narcolepsy. Among the vaccines, the effect of Pandemrix was scrutinized more than other vaccines, due to its higher association with an increase of narcolepsy onset. The consequences of using other vaccines which contain same or different adjuvants as Pandemrix, were also analyzed.

  11. Voir toutes les initiatives | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le Fonds canadien de recherche sur la sécurité alimentaire internationale du CRDI finance des projets de recherche appliquée pouvant avoir une incidence considérable sur l'agriculture et la nutrition dans les pays en développement. Le FCRSAI, qui soutient des partenariats réunissant des établissements de recherche ...

  12. Changements climatiques | Page 37 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Langue French. Dans domaine de la recherche sur la gestion des ressources naturelles, les meilleurs modèles sont ceux qui, lors de la prise de décision et de l'identification du projet de recherche et des paramètres de développement, intègrent la participation des membres de la collectivité, des équipes de recherche ou ...

  13. Silicon detectors

    International Nuclear Information System (INIS)

    Klanner, R.

    1984-08-01

    The status and recent progress of silicon detectors for high energy physics is reviewed. Emphasis is put on detectors with high spatial resolution and the use of silicon detectors in calorimeters. (orig.)

  14. The data acquisition system for the HERA H1 experiment

    International Nuclear Information System (INIS)

    Haynes, W.J.

    1990-06-01

    The HERA ep collider will set new challenges for the acquisition of data from large particle physics experiments. Short bunch-crossing times combined with high data rates imply sophisticated designs based on current technology. This paper describes how a multi-microprocessor system is being used at the H1 experiment. (author)

  15. The H^{-1}-norm of tubular neighbourhoods of curves

    NARCIS (Netherlands)

    Gennip, van Y.; Peletier, M.A.

    2011-01-01

    We study the H^{-1}-norm of the function 1 on tubular neighbourhoods of curves in R^2. We take the limit of small thickness epsilon, and we prove two different asymptotic results. The first is an asymptotic development for a fixed curve in the limit epsilon to 0, containing contributions from the

  16. Spread of H1N1 within Households

    Centers for Disease Control (CDC) Podcasts

    This podcast describes an investigation into how H1N1 was spreading within households during the initial days of the pandemic in Texas. CDC's Dr. Oliver Morgan discusses what investigators learned about the role that children played in introducing the virus into households and spreading flu.

  17. Influenza A (H1N1) pneumonia: HRCT findings

    Energy Technology Data Exchange (ETDEWEB)

    Amorim, Viviane Brandao; Rodrigues, Rosana Souza; Barreto, Miriam Menna; Marchiori, Edson, E-mail: edmarchiori@gmail.com [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil); Zanetti, Glaucia [Escola de Medicina de Petropolis, RJ (Brazil); Hochhegger, Bruno [Santa Casa de Misericordia de Porto Alegre, RS (Brazil)

    2013-11-01

    Objective: to describe aspects found on HRCT scans of the chest in patients infected with the influenza A (H1N1) virus. Methods: we retrospectively analyzed the HRCT scans of 71 patients (38 females and 33 males) with H1N1 infection, confirmed through laboratory tests, between July and September of 2009. The HRCT scans were interpreted by two thoracic radiologists independently, and in case of disagreement, the decisions were made by consensus. Results: the most common HRCT findings were ground-glass opacities (85%), consolidation (64%), or a combination of ground-glass opacities and consolidation (58%). Other findings were airspace nodules (25%), bronchial wall thickening (25%), interlobular septal thickening (21%), crazy-paving pattern (15%), perilobular pattern (3%), and air trapping (3%). The findings were frequently bilateral (89%), with a random distribution (68%). Pleural effusion, when observed, was typically minimal. No lymphadenopathy was identified. Conclusions: the most common findings were ground-glass opacities and consolidations, or a combination of both. Involvement was commonly bilateral with no axial or cranio caudal predominance in the distribution. Although the major tomographic findings in H1N1 infection are nonspecific, it is important to recognize such findings in order to include infection with the H1N1 virus in the differential diagnosis of respiratory symptoms. (author)

  18. Charge transfer in H2+-H(1s) collisions

    International Nuclear Information System (INIS)

    Errea, L.F.; Macias, A.; Mendez, L.; Rabadan, I.; Riera, A.

    2005-01-01

    We present an ab initio study of H 2 + +H(1s) collisions at H 2 + impact energies between 0.4 and 50keV. Cross sections are obtained within the sudden approximation for rotation and vibration of the diatomic molecule. We have found that anisotropy effects are crucial to correctly describe this system in this energy range

  19. H1N1 Influenza A hos mennesker og svin

    DEFF Research Database (Denmark)

    Larsen, Lars Erik

    2009-01-01

    Den nye pandemiske influenza A stamme H1N1 er hovedsagelig et nyt virus, som spredes mellem mennesker, men virusset er formodentlig opstået ved blanding af to svineinfluenza-virus og har derfor bibeholdt evnen til at kunne smitte fra mennesker til svin og fra svin til svin. Det er derfor vigtigt...

  20. Pneumococcal Pneumonia and Pandemic H1N1

    Centers for Disease Control (CDC) Podcasts

    2012-06-06

    Dr. George Nelson, a CDC medical officer, discusses the relationship between pneumococcal pneumonia and Pandemic H1N1.  Created: 6/6/2012 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 6/6/2012.

  1. Identification of swine H1N2/pandemic H1N1 reassortant influenza virus in pigs, United States.

    Science.gov (United States)

    Ali, Ahmed; Khatri, Mahesh; Wang, Leyi; Saif, Yehia M; Lee, Chang-Won

    2012-07-06

    In October and November 2010, novel H1N2 reassortant influenza viruses were identified from pigs showing mild respiratory signs that included cough and depression. Sequence and phylogenetic analysis showed that the novel H1N2 reassortants possesses HA and NA genes derived from recent H1N2 swine isolates similar to those isolated from Midwest. Compared to the majority of reported reassortants, both viruses preserved human-like host restrictive and putative antigenic sites in their HA and NA genes. The four internal genes, PB2, PB1, PA, and NS were similar to the contemporary swine triple reassortant viruses' internal genes (TRIG). Interestingly, NP and M genes of the novel reassortants were derived from the 2009 pandemic H1N1. The NP and M proteins of the two isolates demonstrated one (E16G) and four (G34A, D53E, I109T, and V313I) amino acid changes in the M2 and NP proteins, respectively. Similar amino acid changes were also noticed upon incorporation of the 2009 pandemic H1N1 NP in other reassortant viruses reported in the U.S. Thus the role of those amino acids in relation to host adaptation need to be further investigated. The reassortments of pandemic H1N1 with swine influenza viruses and the potential of interspecies transmission of these reassortants from swine to other species including human indicate the importance of systematic surveillance of swine population to determine the origin, the prevalence of similar reassortants in the U.S. and their impact on both swine production and public health. Copyright © 2012 Elsevier B.V. All rights reserved.

  2. La recherche alpine aujourd’hui

    Directory of Open Access Journals (Sweden)

    Jean-Jacques Brun

    2009-06-01

    Full Text Available Alpine research benefits from several international coordination networks, only one of which – ISCAR (the International Scientific Committee on Research in the Alps – works solely in the Alpine arc. The creation of ISCAR is a consequence of the input and involvement of various Alpine partners around the Alpine Convention. Alpine research now aims to promote an integrated vision of Alpine territories focusing on creating and maintaining spatial and temporal networks of sustainable relationships between humans and the other components of the ecosphere. It combines resource usage with conservation of the biological and cultural diversity that makes up the Alpine identity. This article aims to show: (1 how international Alpine research coordination is organised; (2 the role played by the Alpine Convention as a framework of reference for specifically Alpine research; and (3 the role that the ISCAR international commit-tee and the Interreg “Alpine Space” programmes play in uniting research around territorial challenges relating to biodiversity conservation and territorial development.La recherche sur les Alpes bénéficie de plusieurs réseaux de coordination internationaux dont un seul, le comité international recherche alpine (ISCAR, se consacre exclusivement à l’arc alpin. La création de l’ISCAR est une retombée de la mobilisation des divers partenaires alpins autour de la mise en place de la Convention alpine. Aujourd’hui, la recherche alpine vise à promouvoir une vision intégrée des territoires centrée sur la création et le maintien d’un réseau spatial et temporel de relations durables entre les hommes et les autres composantes de l’écosphère. Elle associe étroitement la mise en valeur des ressources et la conservation des diversités biologiques et culturelles qui constituent l’identité alpine. Cet article a pour ambition de montrer : (1 comment s’organise la coordination internationale des recherches sur les

  3. Molecular treatment of the ion-pair formation reaction in H(1s) + H(1s) collisions

    Energy Technology Data Exchange (ETDEWEB)

    Borondo, F.; Martin, F.; Yaez, M.

    1987-01-01

    All the available theoretical calculations of the cross section for the ion-pair formation reaction H(1s)+H(1s)..-->..H/sup +/H/sup -/(1s/sup 2/) have been performed using methods that are only valid at high collision energies. They get good agreement with the experiments for impact energies greater than 25 keV, but fail completely at smaller energies. In this work we report the cross section for this reaction at impact energies less than 10 keV, calculated in the framework of the impact-parameter approximation and using the molecular method with a common translation factor.

  4. Imaging MOSS tomographic system for H-1NF

    International Nuclear Information System (INIS)

    Glass, F.; Howard, J.

    1999-01-01

    A tomographic diagnostic utilising the Modulated Optical Solid-State spectrometer (MOSS) is planned for the H-1NF stellarator at the ANU. It is designed to create two-dimensional temperature or velocity maps of a poloidal cross-section of the high temperature plasma of H-1NF. The introduction of the MOSS spectrometers has enabled the development of several diagnostics to be used on the H-1NF stellerator. The MOSS spectrometer allows calculations of the plasma temperature and bulk velocity based on a line-integrated measurement of light emitted from electronic transitions within the plasma. A tomographic system utilising a rotatable multi-view ring apparatus and spatial multiplexing through a MOSS spectrometer is currently being developed. The ring apparatus is placed inside the H-1NF vessel and encircles the plasma. Multiple line-of-sight views collect light through a poloidal cross-section of the plasma and the emitted light is coupled into large core optical fibres. The transmitted light, via the optical fibre bundle, is then imaged through a large aperture MOSS spectrometer and onto another optical fibre array. Each fibre is then fed into a photomultiplier tube for signal detection. Characterisation of the properties of the lithium niobate (LiNbO 3 ) crystal used for modulation in the MOSS spectrometer is being undertaken to account for ray divergence in the imaging system. Tomographic techniques enable the construction of a temperature or velocity map of the poloidal cross-section. Rotating the ring apparatus to a new viewing position for the next pulse of plasma should allow an accurate picture to be built up based on the reproducibility of the plasma pulses. It is expected that initial testing of the system will begin in May when H-1NF begins operations at 0.5 Telsa field strength

  5. Accreditation to supervise research; Habilitation a diriger des recherches

    Energy Technology Data Exchange (ETDEWEB)

    Calvet, D.

    2011-03-21

    In this document the author reviews his works between 1995 and 2010. First, the development of a silicon pixel detector is detailed, the purpose of this detector was to improve the forward proton spectrometer of the H1 experiment at DESY. The works made to develop the reading circuits of the pixel detector are presented, particularly the design of the test bench for the testing of these circuits and the simulation of their behaviour in realistic environment. The second part describes the design of the front electronic for the data acquisition of the calorimeter detector of ATLAS (TileCal) and its testing system (MobiDICK). The software for the control system of the laser calibration of TileCal is detailed. The last part gives an account of the author's activities in the field of science popularization through the 'Cosmophone' and knowledge dissemination. The Cosmophone is a particle detector that turns the passage of particles into sounds in order to make the general public more aware of the presence of particles

  6. Citrullination regulates pluripotency and histone H1 binding to chromatin

    DEFF Research Database (Denmark)

    Christophorou, Maria A; Castelo-Branco, Gonçalo; Halley-Stott, Richard P

    2014-01-01

    citrullination of core histones has been linked to transcriptional regulation and the DNA damage response. PADI4 (also called PAD4 or PADV), the only PADI with a nuclear localization signal, was previously shown to act in myeloid cells where it mediates profound chromatin decondensation during the innate immune...... and activating their expression. Its inhibition lowers the percentage of pluripotent cells in the early mouse embryo and significantly reduces reprogramming efficiency. Using an unbiased proteomic approach we identify linker histone H1 variants, which are involved in the generation of compact chromatin, as novel...... PADI4 substrates. Citrullination of a single arginine residue within the DNA-binding site of H1 results in its displacement from chromatin and global chromatin decondensation. Together, these results uncover a role for citrullination in the regulation of pluripotency and provide new mechanistic...

  7. Data storage and data access at H1

    International Nuclear Information System (INIS)

    Gerhards, R.; Kleinwort, C.; Kruener-Marquis, U.; Niebergall, F.

    1996-01-01

    The electron proton collider HERA at the DESY laboratory in Hamburg and the H1 experiment are now in successful operation for more than three years. The H1 experiment is logging data at an average rate of 500KB/s which results in a yearly raw data volume of several Terabytes. The data are reconstructed with a delay of only a few hours, also yielding several Terabytes of reconstructed data after physics oriented event classification. Physics analysis is performed on a SGI Challenge computer, equipped with about 500 GB of disk and, since a couple of months, direct access to a Storage Tek ACS 4400 silo. The disk space is mainly devoted to store the reconstructed data in very compressed format (typically 5 to 10 KB per event). This allows for very efficient and fast physics analysis. Monte Carlo data, on the other hand, are kept in the ACS silo and staged to disk on demand. (author)

  8. Ten years of Object-Oriented analysis on H1

    International Nuclear Information System (INIS)

    Laycock, Paul

    2012-01-01

    Over a decade ago, the H1 Collaboration decided to embrace the object-oriented paradigm and completely redesign its data analysis model and data storage format. The event data model, based on the ROOT framework, consists of three layers - tracks and calorimeter clusters, identified particles and finally event summary data - with a singleton class providing unified access. This original solution was then augmented with a fourth layer containing user-defined objects. This contribution will summarise the history of the solutions used, from modifications to the original design, to the evolution of the high-level end-user analysis object framework which is used by H1 today. Several important issues are addressed - the portability of expert knowledge to increase the efficiency of data analysis, the flexibility of the framework to incorporate new analyses, the performance and ease of use, and lessons learned for future projects.

  9. Résultats de recherche | Page 16 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Accélérer la mise au point d'un vaccin contre le virus de la peste porcine africaine grâce à la biologie synthétique ... La présente demande s'adresse aux instituts indépendants (« think tanks ») voués à la recherche sur les politiques, établis au Myanmar, et dont les recherches sont axées sur des problèmes de niveau ...

  10. Results from the H1 experiment at HERA

    International Nuclear Information System (INIS)

    Krasny, M.W.

    1993-01-01

    Results obtained by the H1 collaboration at HERA from the analysis of the data collected in 1992 - the first year of HERA operation are presented. Measurements of the total photoproduction cross-section and the inclusive jet cross-section in γp scattering, the structure function F 2 (x,Q 2 ) and the jet rates in deep inelastic ep scattering, and results of direct searches for leptoquarks are discussed. (author) 37 refs., 6 figs

  11. Underreporting of 2009 H1N1 Influenza Cases

    Centers for Disease Control (CDC) Podcasts

    Influenza cases are difficult to track because many people don't go to the doctor or get tested for flu when they're sick. The first months of the 2009 H1N1 influenza pandemic were no different. In this podcast, CDC's Dr. Carrie Reed discusses a study in the December issue of Emerging Infectious Diseases that looked at the actual number of cases reported and estimated the true number of cases when correcting for underreporting.

  12. Spread of H1N1 within Households

    Centers for Disease Control (CDC) Podcasts

    2010-03-29

    This podcast describes an investigation into how H1N1 was spreading within households during the initial days of the pandemic in Texas. CDC's Dr. Oliver Morgan discusses what investigators learned about the role that children played in introducing the virus into households and spreading flu.  Created: 3/29/2010 by Emerging Infectious Diseases.   Date Released: 3/29/2010.

  13. Contextualizing ethics: ventilators, H1N1 and marginalized populations.

    Science.gov (United States)

    Silva, Diego S; Nie, Jason X; Rossiter, Kate; Sahni, Sachin; Upshur, Ross E G

    2010-01-01

    If the H1N1 pandemic worsens, there may not be enough ventilated beds to care for all persons with respiratory failure. To date, researchers who explicitly discuss the ethics of intensive care unit admission and the allocation of ventilators during an influenza pandemic have based criteria predominantly on the principles of utility and efficiency, that is, promoting actions that maximize the greatest good for the greatest number of people. However, haphazardly applying utility and efficiency potentially disadvantages marginalized populations who might be at increased risk of severe reactions to H1N1. In Canada, Aboriginals represent 3% of Canadians, yet 11% of H1N1 cases requiring hospitalization involve Aboriginal persons. Aboriginal persons suffer from high rates of obesity due to socio-economic inequalities. Obesity is also a risk factor for severe H1N1 reactions. Yet, since obesity is found to increase the duration of stay in ventilated beds and a long stay is not considered an optimal use of ventilators, applying the principles of utility and efficiency may magnify existing social inequalities. Although promoting utility and efficiency is important, other ethical principles, such as equity and need, require thoughtful consideration and implementation. Furthermore, since public resources are being used to address a public health hazard, the viewpoints of the public, and specifically stakeholders who will be disproportionately affected, should inform decision-makers. Finally, giving attention to the needs and rights of marginalized populations means that ventilators should not be allocated based on criteria that exacerbate the social injustices faced by these groups of people.

  14. The H1 SPACAL time-to-digital converter system

    International Nuclear Information System (INIS)

    Eisenhandler, E.; Landon, M.; Thompson, G.

    1995-01-01

    This paper describes a pipelined 1,400-channel Time-to-Digital Converter (TDC) system for the H1 Scintillating Fiber Calorimeter, which will soon be installed in the H1 experiment at DESY. The main task of the TDC system is to determine the time of arrival of energy depositions, and send this information from bunch crossings that satisfy the event trigger into the H1 data acquisition system. In addition, the TDC system must monitor the timing trigger, which vetoes bunch crossings that contain too much background energy. Products of the interaction are separated from background on the basis of their different times of arrival with respect to the bunch crossing clock. For this monitoring the TDC system uses automatic on-board histogramming hardware that produces a family of histograms for each of 1,400 channels. The TDC function is performed by the TMC1004 ASIC. The system digitizes over a range of 32ns per bunch crossing with 1ns bins and a precision of 1ns. Because of the way the TMC1004 is designed, it is possible to vary the size of the bins between 0.6ns and 3ns by trading off measurement range for bin size. The system occupies two 9U VME crates

  15. Renforcement de la recherche en sciences sociales en Iraq - phase ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    appuyer sur le travail accompli au cours de la première phase du projet (103936) pour concevoir et offrir une formation en méthodes et techniques de recherche en sciences sociales destinée à de jeunes intellectuels et réaliser des recherches sur ...

  16. Financing Innovation | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    27 sept. 2013 ... As the fifth volume in a series of five books bringing together the results of intensive research on the national systems of innovation (NSI) in the BRICS countries – Brazil, Russia, India, ... Les équipes de recherche de calibre mondial se concentreront sur les nouvelles frontières de la recherche sur le cancer.

  17. Changements climatiques | Page 39 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le Moyen-Orient et l'Afrique du Nord connaissent une urbanisation effrénée qui entraîne un grave stress hydrique et nuit à la production alimentaire. Mais la recherche montre comment l'expansion urbaine et la croissance agricole peuvent aller de pair. Axe de recherche. Examiner en quoi les changements climatiques et ...

  18. Administrateur de subventions (h/f) | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... au projet (Protocole d'accord fixant les conditions de la subvention, Accord de subvention de soutien à la recherche, contrats de bourses de recherche, contrats d'emploi des titulaires de bourses, contrats de service et avis de subventions de déplacement) à porter à la signature de l'agent d'administration de subventions.

  19. Des statistiques essentielles | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    un programme de recherche sur le terrain mené pour le compte du Centre international de recherche sur les maladies diarrhéiques. Au début, les accoucheuses traditionnelles faisaient état de variations démographiques hebdomadaires dans ...

  20. Publications | Page 192 | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    L''objectif de cette étude est d''établir des relations entre les perceptions locales ... comme sujet d''une grande pertinence dans la recherche en sciences sociales. ... La recherche sur le rôle économique et social du secteur informel des TIC est ...

  1. Qu'est-ce qu'une bonne recherche?

    International Development Research Centre (IDRC) Digital Library (Canada)

    Corey Piccioni

    types de recherches présentent également des différences sur les plans de .... Dans le cas de la recherche qualitative, le critère de la validité a été jugé important par ...... Feminist research: definitions, methodology, methods and evaluation.

  2. À propos du CRDI | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le Centre de recherches pour le développement international (CRDI) finance des travaux de recherche dans les pays en développement afin d'y favoriser la croissance, de réduire la pauvreté et d'impulser des changements positifs à grande échelle.

  3. Realization of a second level neural network trigger for the H1 experiment at HERA

    International Nuclear Information System (INIS)

    Koehne, J.K.; Fent, J.; Froechtenicht, W.; Gaede, F.; Gruber, A.; Haberer, W.; Kiesling, C.; Kobler, T.; Moeck, J.; Wegner, A.; Goldner, D.; Kraemerkaemper, T.; Kolander, M.; Kolanoski, H.

    1997-01-01

    Since 1996 the H1 experiment is fully equipped with two independent fast pattern recognition systems operating as second level triggers (L2). The decision time is 20 μs. One of the two is the neural network trigger. It runs an array of presently ten VME-boards with CNAPS 1064 chips (20 MHz, 128 Mcps) by adaptive solutions. The input trigger data from the detector components arrive in various formats on a 8 x 16 bit wide 10 MHz bus. Before usable as 8-bit input values to the CNAPS they are preprocessed by several bit-manipulating algorithms and arithmetic functions implemented on XILINX 4008 field programmable gate arrays (FPGA). The startup strategy for the new system is to concentrate on photoproduction channels or low multiplicity final states which so far could only be efficiently triggered with unacceptable high rates. (orig.)

  4. J/ψ and ρ0 meson production at H1

    International Nuclear Information System (INIS)

    Kenyon, I.R.

    1996-01-01

    The production of J/ψ and ρ 0 mesons from e-p collisions, both in Deep Inelastic Scattering (DIS) and at Q 2 ∼ 0, has been studied using the H1 detector at HERA. The features of elastic ρ 0 production at Q 2 ∼ 0 are those expected from the Generalized Vector Dominance Model (VDM). However the elastic DIS ρ 0 and DIS J/ψ production as well as the elastic J/ψ production at Q 2 ∼ 0 all show features consistent with models that are inspired by perturbative QCD (pQCD). This pattern indicates that the appearance of a hard scale in vector meson production (either the quark mass, or large Q 2 ) results in a transition from VDM to pQCD. A final topic is the comparison of inelastic J/ψ production to a prediction from the photon-gluon fusion process in NLO. (author)

  5. Transmutation detectors

    Energy Technology Data Exchange (ETDEWEB)

    Viererbl, L., E-mail: vie@ujv.c [Research Centre Rez Ltd. (Czech Republic); Nuclear Research Institute Rez plc (Czech Republic); Lahodova, Z. [Research Centre Rez Ltd. (Czech Republic); Nuclear Research Institute Rez plc (Czech Republic); Klupak, V. [Nuclear Research Institute Rez plc (Czech Republic); Sus, F. [Research Centre Rez Ltd. (Czech Republic); Nuclear Research Institute Rez plc (Czech Republic); Kucera, J. [Research Centre Rez Ltd. (Czech Republic); Nuclear Physics Institute, Academy of Sciences of the Czech Republic (Czech Republic); Kus, P.; Marek, M. [Research Centre Rez Ltd. (Czech Republic); Nuclear Research Institute Rez plc (Czech Republic)

    2011-03-11

    We have designed a new type of detectors, called transmutation detectors, which can be used primarily for neutron fluence measurement. The transmutation detector method differs from the commonly used activation detector method in evaluation of detector response after irradiation. Instead of radionuclide activity measurement using radiometric methods, the concentration of stable non-gaseous nuclides generated by transmutation in the detector is measured using analytical methods like mass spectrometry. Prospective elements and nuclear reactions for transmutation detectors are listed and initial experimental results are given. The transmutation detector method could be used primarily for long-term measurement of neutron fluence in fission nuclear reactors, but in principle it could be used for any type of radiation that can cause transmutation of nuclides in detectors. This method could also be used for measurement in accelerators or fusion reactors.

  6. Transmutation detectors

    International Nuclear Information System (INIS)

    Viererbl, L.; Lahodova, Z.; Klupak, V.; Sus, F.; Kucera, J.; Kus, P.; Marek, M.

    2011-01-01

    We have designed a new type of detectors, called transmutation detectors, which can be used primarily for neutron fluence measurement. The transmutation detector method differs from the commonly used activation detector method in evaluation of detector response after irradiation. Instead of radionuclide activity measurement using radiometric methods, the concentration of stable non-gaseous nuclides generated by transmutation in the detector is measured using analytical methods like mass spectrometry. Prospective elements and nuclear reactions for transmutation detectors are listed and initial experimental results are given. The transmutation detector method could be used primarily for long-term measurement of neutron fluence in fission nuclear reactors, but in principle it could be used for any type of radiation that can cause transmutation of nuclides in detectors. This method could also be used for measurement in accelerators or fusion reactors.

  7. Résultats de recherche | Page 12 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le programme de recherche Croissance de l'économie et débouchés économiques des femmes (CEDEF) est une initiative de collaboration entre le CRDI, le Department for International Development du Royaume-Uni et la Fondation William et Flora Hewlett. Projet ...

  8. Résultats de recherche | Page 12 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Recherche sur les stratégies de prévention du VIH chez les adolescents. En Afrique, le VIH a des répercussions dévastatrices sur les jeunes. À l'échelle mondiale, les jeunes de 15 à 24 ans représentent près du tiers des nouvelles infections. Projet.

  9. Résultats de recherche | Page 53 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    innovation ? Le cadre de vie offert aux populations en Afrique centrale en général et au Cameroun en particulier, les confronte au quotidien à une variété de sollicitations besoins qui pourraient bénéficier des résultats de la recherche. Published date.

  10. Résultats de recherche | Page 83 | CRDI - Centre de recherches ...

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    Liens entre le savoir et l'innovation dans les services de gestion des déchets solides de trois municipalités du Sri Lanka. Ce projet de recherche-action portera sur l'innovation dans la prestation de services par les administrations locales au Sri Lanka. Projet.

  11. Résultats de recherche | Page 51 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Second Science with Africa Conference : dans quelle mesure l'exemption de la recherche peut-elle promouvoir l'innovation à travers une formulation la plus à même de favoriser l'accès aux connaissances brevetées ? Published date. 1 janvier 2010. Études.

  12. Résultats de recherche | Page 2 | CRDI - Centre de recherches pour ...

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    Programme de leadership sur le climat : Renforcer la résilience de l'Afrique au moyen de la recherche, des politiques et de la pratique. Le renforcement de la résilience de l'Afrique aux changements climatiques exigera l'élaboration et la mise en oeuvre de stratégies efficaces d'adaptation. Projet ...

  13. Résultats de recherche | Page 21 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Des résultats de recherche mènent à la réalisation d'essais de prévention du VIH dans ... Téléphones mobiles, Internet et sexospécificité au Myanmar ... Les formateurs ont immédiatement eu la chance de mettre en pratique leurs nouvelles ...

  14. Résultats de recherche | Page 424 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les enjeux éthiques d'internet en Afrique de l'Ouest : Vers un modèle éthique ... de développement international et les institutions de recherche du monde entier. ... que ce soit dans des situations où une intervention a eu lieu, comme au Koso.

  15. Résultats de recherche | Page 44 | CRDI - Centre de recherches ...

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    Une étude examine les liens qui existent entre la protection sociale et la ... Programme de recherche sur le virus Zika Canada-Amérique latine et ... Le salaire minimum n'est pas toujours le meilleur moyen d'accroître le bien-être social.

  16. Résultats de recherche | Page 13 | CRDI - Centre de recherches ...

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    égalité entre ... À l'approche de 2015, la communauté internationale évalue de façon ... sont-elles capables d'adopter des modes de production plus écologiques ? ... Droits d'auteur · Éthique de la recherche · Politique de libre accès · Politique de ...

  17. Résultats de recherche | Page 9 | CRDI - Centre de recherches pour ...

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    égalité entre ... À l'approche de 2015, la communauté internationale évalue de façon ... sont-elles capables d'adopter des modes de production plus écologiques ? ... Droits d'auteur · Éthique de la recherche · Politique de libre accès · Politique de ...

  18. Résultats de recherche | Page 11 | CRDI - Centre de recherches ...

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    L'objectif général de ce projet de recherche-action est de contribuer à ... et du contrôle des femmes sur les terres et leur participation dans les instances de prise de ... Autonomisation juridique pour atteindre un niveau de gestion équitable, ...

  19. Résultats de recherche | Page 74 | CRDI - Centre de recherches ...

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    Agenda panafricain de recherche sur l'intégration pédagogique des TIC : 3ème Conférence internationale consacrée aux TIC appliquées à l'enseignement, à la formation et au développement, Accra, Ghana, 28-30 mai 2008. Published date. 1 janvier 2008 ...

  20. Résultats de recherche | Page 115 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les pratiques commerciales ou concurrentielles inéquitables constituent une part importante des lois antitrust de nombreux pays. ... le soutien du CRDI, a créé un projet de recherche concertée sur le droit administratif international (Global Administrative Law [GAL] Project) dans le but de faire en sorte que les universitair.

  1. Résultats de recherche | Page 18 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    L'Initiative des conseils subventionnaires de la recherche scientifique en ... en matière de coopération dans les domaines de la science internationale, ... Le CRDI soutient Shirkat Gah afin d'améliorer les droits génésiques des Pakistanaises.

  2. Résultats de recherche | Page 9 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    L'initiative Gouvernance démocratique, droits des femmes et égalité entre les ... est un principe important du programme de coopération internationale du Canada. ... Conseils subventionnaires de la recherche scientifique : un examen des ...

  3. Résultats de recherche | Page 29 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    L'Initiative des conseils subventionnaires de la recherche scientifique en ... en matière de coopération dans les domaines de la science internationale, ... Le CRDI soutient Shirkat Gah afin d'améliorer les droits génésiques des Pakistanaises.

  4. Résultats de recherche | Page 17 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    L'Initiative des conseils subventionnaires de la recherche scientifique en ... en matière de coopération dans les domaines de la science internationale, ... Le CRDI soutient Shirkat Gah afin d'améliorer les droits génésiques des Pakistanaises.

  5. Résultats de recherche | Page 13 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Centre de recherches pour le développement international ... Remarque : Le CRDI a conclu des ententes de coopération scientifique et technique avec certains ... Ces ententes établissent le cadre de coopération et définissent les droits et les ...

  6. Résultats de recherche | Page 13 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... SCIENTIFIQUE ET TECHNIQUE 10 Apply POLITIQUE SCIENTIFIQUE ET ... Phase 2 de l'Initiative canadienne d'immunisation internationale (CIII-2) en Haïti ... Consolidation de centres de recherche sur la reconstruction en Haïti ... au sujet des terres est l'un des grands obstacles à la signature d'accords de paix.

  7. Résultats de recherche | Page 2 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Israel Science Foundation, l'Azrieli Foundation et les Instituts de recherche en s ... (titulaire d'un doctorat de l'Université de Londres) et un chercheur invité à la School of Politics and Sociology du Birkbeck College de l'Université de Londres.

  8. Résultats de recherche | Page 114 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... PETITES ENTREPRISES 37 Apply PETITES ENTREPRISES filter · POLITIQUE .... Régionalisation du recrutement du personnel de santé au Burkina Faso ... de la société civile canadienne d'éclairer les politiques canadiennes sur les droits de la ... Recherche sur les stratégies de prévention du VIH chez les adolescents.

  9. Résultats de recherche | Page 3 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Soutien organisationnel de la phase 2 de l'Initiative Think tank : Science, Technology and Innovation Policy Research Organization. Ce financement contribuera à renforcer le rôle de la Science, Technology and Innovation Policy Research Organization (STIPRO) en tant qu'organisme crédible de recherche sur les ...

  10. Résultats de recherche | Page 433 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Qualitative Research for Tobacco Control : A How-to Introductory Manual for Researchers and Development Practitioners. Ce guide pratique est destiné à encourager les intervenants, où qu'ils se trouvent dans le monde, à s'engager dans la recherche contre le tabac en faisant appel à des méthodes et des outils qualitatifs.

  11. Résultats de recherche | Page 4 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Donner aux filles et aux femmes le pouvoir de décider. Répondre au besoin non satisfait en planification familiale de l'Afrique en intensifiant la recherche sur la santé sexuelle et reproductive et sur la santé des adolescents. Perspectives. CLIMATE CHANGE ADAPTATION GENDER EQUALITY WATER SUPPLY ...

  12. Résultats de recherche | Page 22 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    L'Initiative des conseils subventionnaires de la recherche scientifique en Afrique subsaharienne remporte le prix de la diplomatie scientifique. Les prix de la diplomatie scientifique reconnaissent les réalisations remarquables en matière de coopération dans les domaines de la science internationale, de la technologie et de ...

  13. Résultats de recherche | Page 7 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le programme Droits des femmes et participation citoyenne (DFPC) du CRDI appuie un ensemble de recherches comparatives visant à déterminer si les institutions de démocratie et de gouvernance tiennent compte des droits des femmes et de l'égali. Projet ...

  14. Résultats de recherche | Page 38 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Subventions pour la coopération en recherche entre le Canada, l'Amérique latine et ... Répercussions de la floriculture sur l'environnement et la santé en Équateur ... en plus fréquentes entre des professionnels issus de différentes disciplines.

  15. Résultats de recherche | Page 68 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Participation des pays en développement au Projet international de code barre du vivant. Le code barre ADN est un nouvel outil de recherche taxinomique. Le code barre correspond à une très courte séquence standardisée de l'ADN d'un gène connu. Projet.

  16. Résultats de recherche | Page 4 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Participation des pays en développement au Projet international de code barre du vivant. Le code barre ADN est un nouvel outil de recherche taxinomique. Le code barre correspond à une très courte séquence standardisée de l'ADN d'un gène connu. Projet ...

  17. Résultats de recherche | Page 24 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ISMEA) étant arrivé à mi-parcours, 80 experts africains et canadiens se sont réunis à Dakar, au Sénégal, du 24 au 27 avril 2017 pour discuter des premières constatations du programme et affuter leurs compétences en matière de recherche et ...

  18. Résultats de recherche | Page 3 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    adresse principalement aux établissements de soins de santé du secteur public. ... Une équipe de recherche internationale s'emploie à protéger la santé humaine et l'environnement en améliorant les pratiques agricoles dans quatre pays ...

  19. Résultats de recherche | Page 448 | CRDI - Centre de recherches ...

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    Dominique Charron. À titre de directrice du domaine de programme Agriculture et environnement, Dominique Charron veille au bon déroulement d'activités de recherche ayant pour but d'accroître la productivité de l'agriculture et la sécurité alimentair ...

  20. Résultats de recherche | Page 74 | CRDI - Centre de recherches ...

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    Recherche transnationale : décentralisation en Afrique de l'Ouest et du Centre; apprendre des expériences locales et sectorielles - éducation, eau, santé - cas du Mali (rapport final). Published date. 1 janvier 2011. Rapports. EDUCATION ...

  1. Résultats de recherche | Page 75 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Recherche transnationale : décentralisation en Afrique de l'Ouest et du Centre; apprendre des expériences locales et sectorielles - éducation, eau, santé - cas du Mali (rapport final). Published date. 1 janvier 2011. Rapports. EDUCATION ...

  2. Résultats de recherche | Page 449 | CRDI - Centre de recherches ...

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    À titre de directrice du domaine de programme Agriculture et environnement, Dominique Charron veille au bon déroulement d'activités de recherche ayant pour but d'accroître la productivité de l'agriculture et la sécurité alimentair. Profile. -. Christel Binnie. Christel Binnie est la directrice des communications du Centre.

  3. Résultats de recherche | Page 52 | CRDI - Centre de recherches ...

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    TTI Phase 2 Institutional Support: Advocates Coalition for Development and Environment. Le financement contribuera à renforcer le rôle de l'Advocates Coalition for Development and Environment (ACODE) en tant qu'organisme crédible de recherche sur les politiques publiques en Ouganda, en améliorant sa capacité à ...

  4. Résultats de recherche | Page 26 | CRDI - Centre de recherches ...

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    ISMEA) étant arrivé à mi-parcours, 80 experts africains et canadiens se sont réunis à Dakar, au Sénégal, du 24 au 27 avril 2017 pour discuter des premières constatations du programme et affuter leurs compétences en matière de recherche et ...

  5. Résultats de recherche | Page 8 | CRDI - Centre de recherches pour ...

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    Migrations, sexospécificités et justice sociale : faire le pont entre recherche et ... Depuis 1978, le CRDI permet à la Division des relations internationales de ... Health Bridge - Les TIC au profit de la cueillette et de la gestion des données.

  6. Résultats de recherche | Page 16 | CRDI - Centre de recherches ...

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    Formation en TIC destinée aux personnes handicapées en Amérique latine ... des relations entre les bandes de jeunes et le crime organisé en Jamaïque. Projet. -. Migrations, sexospécificités et justice sociale : faire le pont entre recherche et ...

  7. Résultats de recherche | Page 69 | CRDI - Centre de recherches ...

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    Formation en TIC destinée aux personnes handicapées en Amérique latine ... des relations entre les bandes de jeunes et le crime organisé en Jamaïque. Projet. -. Migrations, sexospécificités et justice sociale : faire le pont entre recherche et ...

  8. Résultats de recherche | Page 3 | CRDI - Centre de recherches pour ...

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    Le CRDI administre l'apport de 20 millions de dollars du gouvernement du Canada à l'expansion du réseau de centre AIMS, l'objectif de l'initiative Next Einstein de l'Institut Africain des Sciences ... Entre chercheurs et entrepreneurs - pour la recherche et la promotion de l'entrepreneuriat en Afrique francophone.

  9. Résultats de recherche | Page 29 | CRDI - Centre de recherches ...

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    Ce projet (PAGE II, pour Policy Analysis on Growth and Employment II) mis en place par le Partenariat en politiques économiques (PEP) soutiendra la recherche qualitative, le développement des capacités et l'interaction avec la sphère des politique. Projet.

  10. Résultats de recherche | Page 36 | CRDI - Centre de recherches ...

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    Recherche sur l'environnement alimentaire urbain obésogène, ses facteurs et les leviers politiques potentiels en Afrique du Sud et au Ghana. Plusieurs pays en développement d'Afrique connaissent une détérioration de l'environnement alimentaire. Projet.

  11. Résultats de recherche | Page 113 | CRDI - Centre de recherches ...

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    . Lancé conjointement par l'Agence canadienne de développement international (ACDI) et le CRDI, le Fonds canadien de recherche sur la sécurité alimentaire internationale (FCRSAI) est doté 61 654 707 CAD (ACDI : 50 000 000 CAD; CRDI ...

  12. Résultats de recherche | Page 26 | CRDI - Centre de recherches ...

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    Projet de recherche sur les sexospécificités et les TIC en Afrique (GRACE) ... Bilan social des services sanitaires dans les collectivités de deux districts de l' ... Les subtilités des interactions entre les technologies de l'information et de la ...

  13. Résultats de recherche | Page 5 | CRDI - Centre de recherches pour ...

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    L'initiative Gouvernance démocratique, droits des femmes et égalité entre les sexes du CRDI appuie un ensemble de recherches comparatives visant à déterminer si les institutions de démocratie et de gouvernance tiennent compte des droits des f. Projet.

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    Cette recherche s'inscrit dans le contexte d'une superposition de deux faits ... de technologies de l'information et de la communication (TIC), ou télécentre, dans ... Le Centro de Tecnologia e Sociedade (CTS - centre pour la technologie et la ...

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    Projet pilote d'utilisation des TIC pour la surveillance de la maladie de Chagas en ... Il s'agit du premier d'une série de neuf projets de recherche financés par le ... Le Centro de Tecnologia e Sociedade (CTS - centre pour la technologie et la ...

  16. Pulmonary function in patients with pandemic H1N1

    Directory of Open Access Journals (Sweden)

    Soraia Koppe

    Full Text Available Abstract Introduction: The influenza A (H1N1 was responsible for the 2009 pandemic, especially with severe pulmonary complications. Objective: To describe characteristics of patients in a university hospital in Curitiba - PR with laboratory diagnosis of influenza A (H1N1 and its post hospital discharge in the 2009 lung function pandemic. Methodology: A retrospective observational study. It was used as a data source the institution Epidemiology Service (SEPIH and spirometry tests of patients who were admitted in 2009, 18 years without lung disease associated and non-pregnant. Descriptive statistics were used and applied Fisher's exact test for relationship between comorbidity and spirometry tests. Results: There were 84 confirmed cases, of these 11 were eligible for the study with a mean age of 44.27 years (± 9.63 and 63.63% males. 54.54% of the 11 patients had comorbidities associated with systemic arterial hypertension (54.54%, diabetes (18.18% and late postoperative period of kidney transplantation (18.18% were the most frequent. Most patients (81.81% had BMI ≥ 25kg / m². The Spirometry test was performed approximately 40.09 (± 15.27 days after discharge, of these, 5 had restrictive pattern and all had abnormal chest radiograph results. There was no statistically significant difference between the results of Spirometry and comorbidities (p=0.24. Conclusions: The group evaluated in this research did not show a direct relationship between Spirometry and comorbidities, but changes in Spirometry in some patients after hospital discharge stood out, suggesting changes in lung function due to influenza A (H1N1.

  17. Underreporting of 2009 H1N1 Influenza Cases

    Centers for Disease Control (CDC) Podcasts

    2009-12-08

    Influenza cases are difficult to track because many people don't go to the doctor or get tested for flu when they're sick. The first months of the 2009 H1N1 influenza pandemic were no different. In this podcast, CDC's Dr. Carrie Reed discusses a study in the December issue of Emerging Infectious Diseases that looked at the actual number of cases reported and estimated the true number of cases when correcting for underreporting.  Created: 12/8/2009 by Emerging Infectious Diseases.   Date Released: 12/8/2009.

  18. Comparative pathology of pigs infected with Korean H1N1, H1N2, or H3N2 swine influenza A viruses

    OpenAIRE

    Lyoo, Kwang-Soo; Kim, Jeong-Ki; Jung, Kwonil; Kang, Bo-Kyu; Song, Daesub

    2014-01-01

    Background The predominant subtypes of swine influenza A virus (SIV) in Korea swine population are H1N1, H1N2, and H3N2. The viruses are genetically close to the classical U.S. H1N1 and triple-reassortant H1N2 and H3N2 viruses, respectively. Comparative pathogenesis caused by Korean H1N1, H1N2, and H3N2 SIV was evaluated in this study. Findings The H3N2 infected pigs had severe scores of gross and histopathological lesions at post-inoculation days (PID) 2, and this then progressively decrease...

  19. Detector Unit

    CERN Multimedia

    1960-01-01

    Original detector unit of the Instituut voor Kernfysisch Onderzoek (IKO) BOL project. This detector unit shows that silicon detectors for nuclear physics particle detection were already developed and in use in the 1960's in Amsterdam. Also the idea of putting 'strips' onto the silicon for high spatial resolution of a particle's impact on the detector were implemented in the BOL project which used 64 of these detector units. The IKO BOL project with its silicon particle detectors was designed, built and operated from 1965 to roughly 1977. Detector Unit of the BOL project: These detectors, notably the ‘checkerboard detector’, were developed during the years 1964-1968 in Amsterdam, The Netherlands, by the Natuurkundig Laboratorium of the N.V. Philips Gloeilampen Fabrieken. This was done in close collaboration with the Instituut voor Kernfysisch Onderzoek (IKO) where the read-out electronics for their use in the BOL Project was developed and produced.

  20. Detector trends

    International Nuclear Information System (INIS)

    Charpak, G.

    1986-01-01

    The author describes briefly the development of detectors for high energy physics experiments. Especially considered are semiconductor microstrip detectors, drift tubes, holographic bubble chambers, scintillating fiber optics, and calorimeters. (HSI).

  1. Infrared detectors

    CERN Document Server

    Rogalski, Antonio

    2010-01-01

    This second edition is fully revised and reorganized, with new chapters concerning third generation and quantum dot detectors, THz detectors, cantilever and antenna coupled detectors, and information on radiometry and IR optics materials. Part IV concerning focal plane arrays is significantly expanded. This book, resembling an encyclopedia of IR detectors, is well illustrated and contains many original references … a really comprehensive book.-F. Sizov, Institute of Semiconductor Physics, National Academy of Sciences, Kiev, Ukraine

  2. About a significance of the avian linker histone (H1) polymorphic ...

    Indian Academy of Sciences (India)

    60

    structural disorder may specify histone H1 interaction with both DNA and partnering proteins through ... from the studies conducted on mammalian model, including the human H1 variants. However ..... Thus, the disparate layout of histone H1.

  3. Experiences at HERA with the H1 data acquisition system

    International Nuclear Information System (INIS)

    Haynes, W.J.

    1992-09-01

    The recently commissioned HERA collider provides a significant pointer to the problems that have to be surmounted in data acquisition systems at the next generation of hadron machines. With bunch crossings, between 30 GeV electrons and 820 GeV protons, 96 nanoseconds apart, the H1 experiment illustrates the application of sophisticated pipelining solutions in the readout of several hundred thousand electronic channels. A modular, multiprocessor design structure emphasis the architectural concepts necessary to cope with large data throughput and yet remain flexible enough to exploit ongoing technological advances in both hardware and software. The range of techniques implemented will be surveyed, covering various digitisation solutions at the front-end through to embedded microprocessor arrays in standard busses controlled by graphics-based stations executing object- orientated code. The experiences gained in developing such a system are also discussed. (orig.)

  4. H1N1 pandemic preparedness and business continuity plan

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-10-15

    SaskPower's H1N1 pandemic preparedness and business continuity plan was designed to prepare SaskPower employees for elevated levels of absenteeism during a potential pandemic. Emergency management and business continuity will be facilitated if critical duties and essential services are maintained without interruption. A layered approach was used to develop a range of response measures designed to meet a range of possible pandemic threats. The plan identified essential activities, tasks and functions and outlined methods of mitigating supply disruptions and possible shortages. Methods of minimizing illness in employees were discussed, as well as methods of maintaining a safe and secure work environment. The measures were developed in accordance with the World Health Organization (WHO) 6 phases of pandemic alert. The plan was also designed to be read by SaskPower's key suppliers in order to ensure their pandemic readiness. 5 tabs.

  5. Results from the H1 experiment at HERA

    International Nuclear Information System (INIS)

    Roeck, A. de

    1994-01-01

    New results from the H1 experiment at HERA on photoproduction, deep inelastic scattering and search for exotic particles are presented. Clear evidence is found for hard scattering in photoproduction interactions. Jets have been observed and used to examine the x γ distribution, indicating the need for a gluonic component in the photon. Hadronic final states and jet cross sections have been measured in deep inelastic scattering. A class of deep inelastic events with diffractive characteristics has been observed. The proton structure function F 2 (x, Q 2 ) has been measured in the new Bjorken-x region 10 -4 -2 and is found to rise with decreasing x. New limits for leptoquarks, squarks and excited electrons have been deduced. (orig.)

  6. Technicon H*1 Hematology System: Optical Design Considerations

    Science.gov (United States)

    Colella, G. M.; Tycko, D. H.; Groner, W.

    1988-06-01

    The Technicon H*1 systemTM is a clinical laboratory flow cytometer which performs a complete hematology profile, providing quantitative information on the various types of cells in a blood sample. A light-scattering method, using a HeNe laser, determines in a single flow channel the red cell count, platelet count, and the distributions of red cell volume, red cell hemoglobin concentration, and platelet volume. To accomplish this the scattered light from each red cell in the sample is measured in real time at two angular intervals. The cell volume and the hemoglobin concentration within the cell are derived from these two measurements. Severe accuracy and precision specifications are placed on the medically important red cell count (RBC) and the mean red cell volume (MCV). From the point of view of optical system design, the dominant factor is the requirement that RBC and MCV have precision and accuracy of the order of 2%. Signal-to-noise and scattering-angle definition requirements dictated the choice of a HeNe laser light source. The optics includes an illumination system for producing a sharply defined, uniformly illuminated scattering region and a detection system which must accurately define the accepted scattering angles. In previous cytometric methods for determining MCV only a single quantity was measured for each cell. Such methods cannot disentangle the independent effects of cell size and hemoglobin concentration on the measurement, thus compromising MCV accuracy. The present double-angle scattering method overcomes this accuracy problem. The H*1 red cell method, the supporting optical design and data demonstrating that the use of this technique eliminates interference between the observed red cell indices are presented.

  7. Ophthalmic antihistamines and H1-H4 receptors.

    Science.gov (United States)

    Wade, Laurie; Bielory, Leonard; Rudner, Shara

    2012-10-01

    Antihistamines exert pharmacologic effects by binding to four histamine receptors (H1-H4) at different affinities, producing variable effects depending on the receptor they predominantly bind to. This review's purpose is to determine the relative potency of antihistamines by comparing their binding affinities to these receptors. Studies on binding affinities of antihistamines to histamine receptors were reviewed and the dissociation constant for inhibitor binding (Ki) analyzed to determine the most and least potent antihistamine for each receptor. We retrieved the binding affinities for nineteen antihistamines. For H1 receptors, pyrilamine exhibited the highest affinity (Ki = 0.8 nM), and thioperamide the lowest (Ki = 280, 000 nM). For H2 receptors, ranitidine exhibited the highest affinity (Ki = 187 nM), and olopatadine the lowest (Ki = 100 ,000 nM). For the recently discovered H3 and H4 receptors, thioperamide exhibited the highest affinity (Ki = 1.1 nM), and olopatadine exhibited the lowest (Ki = 79 ,400 nM), to H3. Data on binding affinities to the H4 receptor exist for: ketotifen, pheniramine, ranitidine, cimetidine and thioperamide. Of these, thioperamide exhibited the highest affinity (Ki = 27 nM), whereas cimetidine and ranitidine exhibited the lowest affinity (Ki = >10, 000 nM) for H4 receptors. This review summarizes the relative potency of antihistamines based on their binding affinities to the four histamine receptors. Although data on binding affinities of antihistamines to the H4 receptor are sparse, it is apparent that further research on these histamine subtypes may open new venues for more direct treatment with a higher therapeutic efficacy on allergic disorders including those affecting the ocular surface.

  8. Calibration of the VIRGO experiment: from the testing of the detector to the search of coalescing binaries with the central interferometer; Calibration de l'experience VIRGO: de l'etalonnage du detecteur a la recherche de signaux de coalescences binaires avec l'interferometre central

    Energy Technology Data Exchange (ETDEWEB)

    Veziant, O

    2003-05-01

    The aim of the VIRGO experiment is the detection of gravitational waves. The detector is based on a Michelson interferometer with three-kilometer long arms. Before the availability of the complete detector, most of the technical choices have been tested on a small scale interferometer (central interferometer or CITF). This allowed to record the first technical data of the experiment. The calibration of the CITF data has been studied in this thesis. This work involved some local operations such as the calibration of the electronics of the detection system, and also some more global operation such as the characterisation of the detector response function. The latter is used to unfold the data from experimental effects and to estimate the detector sensitivity. A monitoring procedure of this response function has been applied to produce a time series of reconstructed data, i.e. data free from experimental distortions. The implementation of VIRGO will make use of an optical calibrator using the radiation pressure of a laser beam to act on the interferometer mirrors and characterize its response. The optical calibrator has been designed and assembled in laboratory and its performances have been measured. The physics analysis following the calibration step was tackled through a coalescing binary search algorithm. The latter was applied both on simulated data and on CITF data in order to estimate the detector noise level and to check the effects of the reconstruction procedure. (author)

  9. La influenza A (H1N1: estado actual del conocimiento Influenza A (H1N1 virus: current information

    Directory of Open Access Journals (Sweden)

    Laura Margarita González Valdés

    2010-03-01

    Full Text Available Se revisó la bibliografía actualizada sobre el tema a partir de los principales buscadores, y reuniones internacionales realizadas sobre la pandemia de la influenza A (H1N1. Se tratan los aspectos relacionados con la historia, la aparición de la pandemia, la biología de la enfermedad, la epidemiología, el cuadro clínico, el tratamiento y el pronóstico y la prevención. La gripe A (H1N1 es una pandemia causada por una variante nueva del virus de la Influenza A que ha sufrido cambios antigénicos en la hemaglutinina y la neuraminidasa. Esto hace que la población sea altamente vulnerable a la infección y produce una sobrecarga temporal enorme a los servicios de salud. El virus se trasmite como otros virus Influenza. Su letalidad es similar a la de la influenza estacional, pero puede incrementarse en personas con factores de riesgo y en adultos jóvenes sanos. El asma y el embarazo parecen ser condiciones de base importantes para incrementar la severidad de la infección. Puede existir cierta protección por inmunidad cruzada con cepas que circularon en el pasado. El espectro clínico va desde personas asintomáticas hasta las formas graves que requieren internación en cuidados intensivos, con rápido deterioro hasta llegar a la insuficiencia respiratoria en un plazo de 24 horas. La vacunación durante la pandemia no parece ser suficientemente efectiva. Son necesarios antivirales (oseltamivir y zanamivir, y las medidas preventivas higiénico-sanitarias son muy eficaces.An updated review using the main search motors and international meetings already celebrated related to Influenza A H1N1 pandemics. Items related to the history, the appearance of the pandemics, the biology of the disease, its epidemiology, clinics, treatment, prognosis and prevention. Grippe A H1N1 is a pandemic caused by a new variant of the Influenza A virus that has suffered antigenic changes in haemaglutinin and neuraminidase. This turns populations more susceptible to

  10. Résultats de recherche | Page 407 | CRDI - Centre de recherches ...

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    403 · 404 · 405 · 406; 407; 408 · 409 · 410 · 411 … suivant › · dernier » · Ce que nous faisons · Financement · Ressources · À propos du CRDI. Savoir. Innovation. Solutions. Carrières · Communiquez avec nous · Plan du site · Droits d'auteur · Éthique de la recherche · Politique de libre accès · Politique de confidentialité ...

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    Renforcement des capacités en vue d'essais cliniques en matière de prévention du VIH/sida. L'Agence canadienne de développement international (ACDI) finance le programme de renforcement des capacités pour des essais en matière de prévention du VIH/sida en Afrique sous l'égide de l'Initiative de recherche en ...

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    Renforcement des capacités de recherche associées aux essais cliniques en matière de prévention du VIH/sida. Relativement peu d'installations africaines disposent des capacités cliniques et de laboratoire nécessaires pour concevoir, gérer et mener des essais en matière de prévention du VIH/sida. Projet.

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    Bourses doctorales pour renforcer le leadership en Afrique subsaharienne dans la recherche sur la prévention du VIH. L'Afrique demeure la région la plus durement touchée par l'épidémie de sida, et la prévention du VIH/sida demeure une priorité mondiale en matière de santé.

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    Cette subvention aide à transférer les activités d'élaboration des indices mondiaux de dons privés du Center for Global Prosperity de l'Hudson Institute à la Lilly Family School of Philanthropy de l'Université de l'Indiana. Projet. Réseau d'échanges et de recherche dans les deltas de l'océan Indien occidental. Le réseau ...

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    Recherche sur les systèmes d'innovation et l'inclusion sociale dans les économies émergentes (les pays BRICS) et ailleurs. Comment la science, la technologie et l'innovation peuvent-elles contribuer à la réduction de la pauvreté et au développement inclusif, en particulier au Brésil, en Russie, en Inde, en Chine et en ...

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    Solutionner les problèmes du système d'autobus urbain au Salvador. Un trajet en autobus public au Salvador peut être une expérience périlleuse, mais un projet de recherche contribue à améliorer ce système de transport qui dessert des millions de gens. Date de publication. 19 juillet 2017. Research in Action. Economic ...

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    À l'approche de 2015, la communauté internationale évalue de façon critique la ... La participation accrue des femmes au marché du travail en Amérique latine a ... sont-elles capables d'adopter des modes de production plus écologiques ? ... Droits d'auteur · Éthique de la recherche · Politique de libre accès · Politique de ...

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    ... de recherche internationale sur l'adaptation aux changements climatiques 5 ... Dans les pays en développement, des millions d'enfants n'ont pas accès à une ... Les plateformes numériques de marché telles qu'AirBnB et Uber, parfois ... en réseau transforme les modes d'accès à l'information partout dans le monde.

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    Interventions de recherche rapides de l'International Crisis Group - s'attaquer aux défis en matière de gouvernance et de sécurité. Au cours des derniers mois, des centaines de milliers de citoyens en Algérie, au Maroc et en Tunisie se sont mobilisés pour exiger une plus grande responsabilité et légitimité du gouvernement ...

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    L'Inde et le Sri Lanka sont d'importants producteurs de légumes et de fruits tropicaux, mais ils enregistrent chaque année des pertes après récolte atteignant de 35 % à 40 % qui sont évaluées à environ 800 millions de dollars. Projet. Consortium de recherche pour le développement de l'agriculture en Haïti. Même avant le ...

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    33 · 34 · 35 · 36; 37; 38 · 39 · 40 · 41 … suivant › · dernier » · Ce que nous faisons · Financement · Ressources · À propos du CRDI. Savoir. Innovation. Solutions. Carrières · Communiquez avec nous · Plan du site · Droits d'auteur · Éthique de la recherche · Politique de libre accès · Politique de confidentialité · Transparence ...

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    Le projet régional de recherche-développement s''est proposé de trouver des solutions appropriées afin de contribuer à la fois à l''amélioration de la gestion des ressources forestières et à la réduction de la pauvreté des communautés qui en dépen. Published date. 30 septembre 2012. Rapports. AGROPASTEURS ...

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    Centre de recherches pour le développement international Gouvernement du Canada .... la faim dans les collectivités agricoles du Sud où les ressources sont limitées. ... de la société civile au processus de réforme de l'éducation nationale. ... compétition écosystèmes et santé humaine en Afrique de l'Ouest (100772).

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    ... Afrique et en Asie 4 Apply Initiative de recherche concertée sur l'adaptation en Afrique ... L'harmonisation de la politique nationale en matière de S-T avec la Stratégie nationale ... Paix, sécurité humaine et développement durable en Afrique ... Les Indiennes de tous les milieux disposent de droits extrêmement limités en ...

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    L'agriculture au service de l'amélioration de la nutrition et de la santé: soutien à un programme du Groupe consultatif pour la recherche agricole. L'agriculture a fait des progrès remarquables au cours des dernières décennies, mais on ne peut en dire autant quant à l'amélioration de la nutrition et de la santé des pauvres ...

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    Bourse de perfectionnement professionnel : Agriculture et sécurité alimentaire ... Appel à notes conceptuelles pour le projet de recherche sur l'égalité des sexes et la décentralisation au Myanmar ... Une nouvelle stratégie de sécurité alimentaire et nutritionnelle qui établit des liens entre l'agriculture, la santé et la nutrition.

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    ... SCIENTIFIQUE ET TECHNIQUE 10 Apply POLITIQUE SCIENTIFIQUE ET ... Juristes et économistes internationaux contre la pauvreté (JEICP) est un ... Subventions pour la coopération en recherche entre le Canada et l'Afrique ... Brésil, Paraguay et Uruguay) des droits, de la démocratie et de l'intégration régionale. Projet.

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    Sécurité alimentaire en Afrique : fonds Cultiver l'avenir de l'Afrique 2. Le présent appel a pour but d'appuyer des travaux de recherche appliquée de pointe menés sur le terrain ou en laboratoire qui sont susceptibles d'entraîner d'importantes retombées et de permettre d'obtenir des résultats innovants, tout spécialement p.

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    MERCOSUR : recherche et intégration économiques - phase IV. Le Red Mercosur de Investigaciones Económicas (Red Mercosur) a été créé en 1998 à la suite d'un projet subventionné par le CRDI visant à fournir un mécanisme de soutien technique et une « optique régionale » (à la différence des optiques nati. Projet ...

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    ... de recherches pour le développement international (CRDI) ont jeté un regard critique sur la manière dont les technologies de l'information et de la communication (TIC) ... Ejercicio de los derechos y participación de las mujeres en los espacios locales: Promesas y realidades de la descentralización en América Latina.

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    Plateforme de recherche sur la protection sociale, l'inclusion financière et les TIC financée par plusieurs bailleurs de fonds ... Les entrepreneurs migrants représentent une force appréciable au sein du secteur non structuré en Afrique australe; or, leur rôle demeure bien souvent invisible aux yeux des responsables des ...

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    Le rôle de l'IL6 dans le cancer du foie lié à l'hépatopathie métabolique. Le cancer du foie est souvent mortel. Il n'existe que très peu ... Chaire de recherche trilatérale Canada – Afrique du Sud sur les changements climatiques et les interactions entre l'humain et la faune. La diminution de la nourriture disponible à la faune ...

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    La recherche présentée dans cet ouvrage démontre comment on utilise des données de SIG pour illustrer des relations de cause à effet entre les conditions de l'environnement et la santé. Publication Date. 1 décembre 1995. Livres. La guerre du tabac : L'expérience canadienne. La guerre du tabac décrit le combat que se ...

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    ... DE SANTÉ filter · Coopération internationale 22 Apply Coopération ... de la pauvreté en Afrique de l'Est avec des liens entre la recherche et les médias ... de professionnels des départements des sciences de la santé, de médecine, ... Pour offrir des services de santé publique équitables dans des contextes où les ...

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    Il s'agit du cinquième ouvrage d'une collection qui en compte cinq et qui collige les résultats de recherches intensives sur les systèmes d'innovation nationaux dans les pays BRICS : le Brésil, la Russie, l'Inde, la Chine et l'Afrique du Sud. Publication Date. 27 septembre 2013. Livres ...

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    L'appel à notes conceptuelles sur la dimension économique de la lutte antitabac dans les pays à faible revenu et les pays à revenu intermédiaire (PFR-PRI) offre jusqu'à 1 million de CAD sur un maximum de quatre ans pour appuyer des recherches fond. Region. North and Central America. Deadline. 15 décembre 2017.

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    Les appels à propositions de recherche sur la mise en œuvre s'inscrivent dans le cadre des objectifs du programme Santé des mères et des enfants du CRDI, qui contribue à améliorer la vie des femmes, des enfants et des adolescents en soutenant des rec. Deadline. 23 mai 2017. Grants and Awards ...

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    Une équipe de recherche internationale s'emploie à protéger la santé humaine et l'environnement en améliorant les pratiques agricoles dans quatre pays d'Asie. En vedette. Development Gender. Le monde a besoin de plus de femmes scientifiques. Les femmes sont très sous-représentées en sciences, ne constituant que ...

  19. Résultats de recherche | Page 29 | CRDI - Centre de recherches ...

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    Quatre éléments clés pour favoriser la santé et le bien-être pour tous. Cinq consultations régionales ont permis d'explorer le rôle des instituts de recherche et des établissements universitaires en ce qui a trait à la mise en oeuvre et au suivi des objectifs. Date de publication. 14 septembre 2017. Projet.

  20. Résultats de recherche | Page 16 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Systèmes d'information sanitaire ou santé sexuelle et reproductive des adolescents au Moyen-Orient et en Afrique du Nord. Les appels à propositions de recherche sur la mise en œuvre s'inscrivent dans le cadre des objectifs du programme Santé des mères et des enfants du CRDI, qui contribue à améliorer la vie des ...

  1. Résultats de recherche | Page 8 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... basée sur l'estime de soi pour renforcer l'autonomisation chez les adol. Ce projet de recherche action vise à réduire les grossesses précoces au Benin à travers le développement et la promotion d'une intervention innovante et basée sur les données probantes, conciliant la santé sexuelle et reproductive, l'estime de soi.

  2. Résultats de recherche | Page 10 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... basée sur l'estime de soi pour renforcer l'autonomisation chez les adol. Ce projet de recherche action vise à réduire les grossesses précoces au Benin à travers le développement et la promotion d'une intervention innovante et basée sur les données probantes, conciliant la santé sexuelle et reproductive, l'estime de soi.

  3. Résultats de recherche | Page 32 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Élaborer une stratégie de recherche sur les légumineuses ... Améliorer les perspectives et les moyens de subsistance pour les communautés marginalisées en Égypte grâce à l'utilisation d'outils numériques ... La lutte contre l'inégalité en ligne : Mettre les plateformes numériques au service du développement inclusif.

  4. Résultats de recherche | Page 14 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Systèmes d'information sanitaire ou santé sexuelle et reproductive des adolescents en Afrique de l'Ouest. Les appels à propositions de recherche sur la mise en œuvre s'inscrivent dans le cadre des objectifs du programme Santé des mères et des enfants du CRDI, qui contribue à améliorer la vie des femmes, des enfants ...

  5. Résultats de recherche | Page 44 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... Croissance de l'économie et débouchés économiques des femmes (38) Apply ... à des niveaux importants de développement économique et humain, il doit y avoir ... La recherche peut jouer un rôle capital dans la création de politiques qui ... mais ils sont rarement évalués ou comptabilisés dans l'économie de marché.

  6. Résultats de recherche | Page 24 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cette recherche porte sur les changements qui se sont produits dans la violence criminelle en milieu urbain concurremment à l'évolution sociopolitique de la Côte d'Ivoire depuis les années 1990. Projet. Nature et acteurs de la violence urbaine en République démocratique du Congo. La République démocratique du ...

  7. Résultats de recherche | Page 4 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le chômage persistant chez les jeunes qui vivent dans des collectivités à faible revenu (on les appelle aussi " jeunes à risque ") est relié en partie au mauvais fonctionnement du marché du travail dans les pays en développement. Projet. -. Bourse de recherche postdoctorale sur l'Amérique centrale et les Caraïbes au ...

  8. Identification of Human H1N2 and Human-Swine Reassortant H1N2 and H1N1 Influenza A Viruses among Pigs in Ontario, Canada (2003 to 2005)†

    OpenAIRE

    Karasin, Alexander I.; Carman, Suzanne; Olsen, Christopher W.

    2006-01-01

    Since 2003, three novel genotypes of H1 influenza viruses have been recovered from Canadian pigs, including a wholly human H1N2 virus and human-swine reassortants. These isolates demonstrate that human-lineage H1N2 viruses are infectious for pigs and that viruses with a human PB1/swine PA/swine PB2 polymerase complex can replicate in pigs.

  9. Physics from the first year of H1 at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Kiesling, C. [Max-Planck-Institut fuer Physik, Muenchen (Germany)

    1994-12-01

    In this report the author summarizes the results from the H1 experiment at HERA, using the data from the first year of running, 1992, when an integrated luminosity of 25 nb{sup {minus}1} has been recorded. These results include photoproduction, the measurement of the deep inelastic scattering, both for neutral current reactions and the search for physics beyond the Standard Model. Apart from the measurement of a moderate rise in the total photoproduction cross section, clear evidence is seen for hard interactions in single particle spectra and jet production, requiring a {open_quotes}resolved{close_quotes} photon as expected in QCD. The investigation of the global properties of hadronic final states in deep inelastic scattering demonstrates the need for further improvement of present QCD models. Evidence is found for a class of events with diffractive characteristics, exhibiting a large gap of hadronic energy flow about the proton direction. The proton structure function F{sub 2}{sup p}(x, Q{sup 2}) has been measured for neutral current events for Bjorken x in the range 10{sup {minus}4} - 10{sup {minus}2} and Q{sup 2} > 5 GeV{sup 2}, showing a steep rise towards small x. Furthermore, using 1993 data, a measurement of the cross section for charged current events is presented, clearly demonstrating, for the first time, the propagator effect of the W boson. Finally, new limits on leptoquarks, leptogluons, and excited electrons have been determined.

  10. Physics from the first year of H1 at HERA

    International Nuclear Information System (INIS)

    Kiesling, C.

    1994-08-01

    In this report we summarize the results from the H1 experiment at HERA, using the data from the first year of running, 1992, where an integrated luminosity of 25 nb -1 has been recorded. These results include photoproduction, the measurement of the deep inelastic scattering, both for neutral current reactions, and the search for physics beyond the standard model. Apart from the measurement of a moderate rise in the total photoproduction cross section, clear evidence is seen for hard interactions in single particle spectra and jet production, requiring a ''resolved'' photon as expected is QCD. The investigation of the global properties of hadronic final states in deep inelastic scattering demonstrates the need for further improvement of present QCD models. Evidence is found for a class of events with diffractive characteristics, exhibiting a large gap of hadronic energy flow about the proton direction. The proton structure function F 2 p (x,Q 2 ) has been measured for neutral current events for Bjorken x in the range 10 -4 - 10 -2 and Q 2 > 5 GeV 2 , showing a steep rise towards small x. Furthermore, using 1993 data, a measurement of the cross section for charged current events is presented, clearly demonstrating, for the first time, the propagator effect of the W boson. Finally, new limits on leptoquarks, leptogluons, and excited electrons have been determined. (orig.)

  11. Recent results from the H1 collaboration at HERA

    International Nuclear Information System (INIS)

    Feltesse, J.

    1994-01-01

    New results from the H1 experiment at the electron-proton collider HERA are reported. Evidence for hard scattering in gamma diffraction in photoproduction events is presented. The hadronic final state in low x deep inelastic scattering (DIS) events has been analyzed. Transverse energy flow and cross section for production of jets at high x j are compared to the expectations of present Monte Carlo programs and to analytical calculations based on the BFKL evolution equation. DIS interactions with no hadronic energy flow in a large interval of rapidity around the incident proton direction are presented. The data are compared to models based on deep inelastic pomeron scattering or on MVD contributions. Measured cross sections for the production of multijet in DIS events at HERA are used to provide a preliminary measurement of the strong coupling constant alpha s , together with the first direct measurement of the gluon density in the proton. The cross section of the charged current process e - p → ν e + hadrons is measured. The effects of the W propagator term is visible for the first time. New limits on leptoquarks, leptogluons, Squarks from R-parity violating supersymmetry and on excited leptons are given. (author). 20 figs., 34 refs

  12. Renforcement de la recherche en sciences sociales en Iraq | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cette subvention permettra à l'Iraq Institute for Strategic Studies d'établir les capacités de recherche en sciences sociales du pays en entreprenant une recherche sur le terrain et une enquête dans trois régions, soit Bagdad, le sud de l'Iraq et le Kurdistan. Il s'agira pour l'institut de cerner les forces et les faiblesses en la ...

  13. Renforcement de la recherche en sciences sociales en Iraq | CRDI ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cette subvention permettra à l'Iraq Institute for Strategic Studies d'établir les capacités de recherche en sciences sociales du pays en entreprenant une recherche sur le terrain et une enquête dans trois régions, soit Bagdad, le sud de l'Iraq et le Kurdistan. Il s'agira pour l'institut de cerner les forces et les faiblesses en la ...

  14. Initiative internationale des chaires de recherche | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Initiative de recherche de sept ans dotée d'un budget de 8 millions de dollars canadiens. L'Initiative internationale des chaires de recherche a pour but de jumeler d'éminents chercheurs d'universités du Canada avec des homologues de pays en développement afin de relever quelques-uns des plus grands défis auxquels ...

  15. La recherche-action participative facilite l'adaptation aux ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Ces travaux comprenaient un riche portefeuille de recherches sur l'adaptation aux changements climatiques dans le secteur de l'agriculture. La méthodologie privilégiée dans le cadre du programme, la recherche-action participative, s'est avérée fructueuse et a permis de mettre au point et de déployer des solutions ...

  16. Bulletin #109 | CRDI - Le Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... offres d'emploi. Appel à propositions de recherche sur les villes résilientes en Amérique latine. Date butoir : 13 juin 2016. Programme de recherche sur le virus Zika Canada-Amérique latine et Caraïbes Date butoir : 12 juillet 2016. POSSIBILITÉS D'EMPLOIS Agent de ressources humaines · Analyste des opérations de TI.

  17. initiative des conseils subventionnaires de la recherche scientifique ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Dorine Odongo

    1.6 Site Web. 1.7 Date de la constitution/de l'incorporation (MM/JJ/AAAA). 1.8 Catégorie (p. ex. institut de recherche,. ONG, think tank, établissement de recherche et d'enseignement universitaires). 1.9 Dirigeant de l'organisme partenaire. (nom complet, titre et adresse courriel). 2.0 Personne-ressource ou coordonnateur.

  18. Principes redditionnels à l'intention des organismes de recherche ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les chercheurs se pencheront sur les principes éthiques qui sous-tendent le cadre redditionnel dans différents contextes et cultures et réévalueront les outils et normes de recherche existants à la lumière du cadre. Le projet aura pour extrants un recueil de bonnes pratiques en matière de recherche et un manuel sur ...

  19. Publications | Page 157 | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à accroître l'impact de nos investissements et à promouvoir la recherche au service du développement. Nous communiquons les ... Research for Development in the Dry Arab Region : The Cactus Flower. Les collectivités établies sur des ...

  20. Voir toutes les initiatives | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Voici les projets appuyés par The William and Flora Hewlett Foundation. Votre recherche n'a donné aucun résultat. Vous pourriez essayer : d'utiliser des synonymes,; d'enlever les filtres de recherche, ou; d'utiliser des mots-clés plus généraux. Nous finançons des chercheurs qui inspirent des changements mondiaux.

  1. Publications | Page 213 | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Projet de recherche : gouvernance et qualité des soins au Bénin; rapport final de recherche (restricted access). Dans le cadre de l''objectif social de l''OMS " Santé pour tous ", les pays africains comme le Bénin ont entrepris des reformes de leur système de santé avec la décentralisation des structures de soins et la mise en ...

  2. Ethiopia : tous les projets | Page 3 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le gouvernement de l'Éthiopie utilise de plus en plus les résultats de recherche dans l'élaboration de ses politiques et un nombre croissant de professionnels axés sur la recherche sont chargés des politiques. Date de début : 2 juillet 2009. End Date: 28 octobre 2014. Sujet: RESEARCH CENTRES, RESEARCH ...

  3. Research and development of a gaseous detector PIM (parallel ionization multiplier) dedicated to particle tracking under high hadron rates; Recherche et developpement d'un detecteur gazeux PIM (Parallel Ionization Multiplier) pour la trajectographie de particules sous un haut flux de hadrons

    Energy Technology Data Exchange (ETDEWEB)

    Beucher, J

    2007-10-15

    PIM (Parallel Ionization Multiplier) is a multi-stage micro-pattern gaseous detector using micro-meshes technology. This new device, based on Micromegas (micro-mesh gaseous structure) detector principle of operation, offers good characteristics for minimum ionizing particles track detection. However, this kind of detectors placed in hadron environment suffers discharges which degrade sensibly the detection efficiency and account for hazard to the front-end electronics. In order to minimize these strong events, it is convenient to perform charges multiplication by several successive steps. Within the framework of a European hadron physics project we have investigated the multi-stage PIM detector for high hadrons flux application. For this part of research and development, a systematic study for many geometrical configurations of a two amplification stages separated with a transfer space operated with the gaseous mixture Ne + 10% CO{sub 2} has been performed. Beam tests realised with high energy hadrons at CERN facility have given that discharges probability could be strongly reduced with a suitable PIM device. A discharges rate lower to 10{sup 9} by incident hadron and a spatial resolution of 51 {mu}m have been measured at the beginning efficiency plateau (>96 %) operating point. (author)

  4. A monoclonal antibody-based ELISA for differential diagnosis of 2009 pandemic H1N1

    Science.gov (United States)

    The swine-origin 2009 pandemic H1N1 virus (pdmH1N1) is genetically related to North American swine H1 influenza viruses and unrelated to human seasonal H1 viruses. Currently, specific diagnosis of pdmH1N1 relies on RT-PCR. In order to develop an assay that does not rely in amplification of the viral...

  5. Comparative pathology of pigs infected with Korean H1N1, H1N2, or H3N2 swine influenza A viruses.

    Science.gov (United States)

    Lyoo, Kwang-Soo; Kim, Jeong-Ki; Jung, Kwonil; Kang, Bo-Kyu; Song, Daesub

    2014-09-24

    The predominant subtypes of swine influenza A virus (SIV) in Korea swine population are H1N1, H1N2, and H3N2. The viruses are genetically close to the classical U.S. H1N1 and triple-reassortant H1N2 and H3N2 viruses, respectively. Comparative pathogenesis caused by Korean H1N1, H1N2, and H3N2 SIV was evaluated in this study. The H3N2 infected pigs had severe scores of gross and histopathological lesions at post-inoculation days (PID) 2, and this then progressively decreased. Both the H1N1 and H1N2 infected pigs lacked gross lesions at PID 2, but they showed moderate to severe pneumonia on PID 4, 7 and 14. The pigs infected with H1N1 had significant scores of gross and histopathological lesions when compared with the other pigs infected with H1N2, H3N2, and mock at PID 14. Mean SIV antigen-positive scores were rarely detected for pigs infected with H1N2 and H3N2 from PID 7, whereas a significantly increased amount of viral antigens were found in the bronchioles and alveolar epithelium of the H1N1infected pigs at PID 14. We demonstrated that Korean SIV subtypes had different pulmonary pathologic patterns. The Korean H3N2 rapidly induced acute lung lesions such as broncho-interstitial pneumonia, while the Korean H1N1 showed longer course of infection as compared to other strains.

  6. Genetic Characterization of H1N1 and H1N2 Influenza A Viruses Circulating in Ontario Pigs in 2012.

    Science.gov (United States)

    Grgić, Helena; Costa, Marcio; Friendship, Robert M; Carman, Susy; Nagy, Éva; Poljak, Zvonimir

    2015-01-01

    The objective of this study was to characterize H1N1 and H1N2 influenza A virus isolates detected during outbreaks of respiratory disease in pig herds in Ontario (Canada) in 2012. Six influenza viruses were included in analysis using full genome sequencing based on the 454 platform. In five H1N1 isolates, all eight segments were genetically related to 2009 pandemic virus (A(H1N1)pdm09). One H1N2 isolate had hemagglutinin (HA), polymerase A (PA) and non-structural (NS) genes closely related to A(H1N1)pdm09, and neuraminidase (NA), matrix (M), polymerase B1 (PB1), polymerase B2 (PB2), and nucleoprotein (NP) genes originating from a triple-reassortant H3N2 virus (tr H3N2). The HA gene of five Ontario H1 isolates exhibited high identity of 99% with the human A(H1N1)pdm09 [A/Mexico/InDRE4487/09] from Mexico, while one Ontario H1N1 isolate had only 96.9% identity with this Mexican virus. Each of the five Ontario H1N1 viruses had between one and four amino acid (aa) changes within five antigenic sites, while one Ontario H1N2 virus had two aa changes within two antigenic sites. Such aa changes in antigenic sites could have an effect on antibody recognition and ultimately have implications for immunization practices. According to aa sequence analysis of the M2 protein, Ontario H1N1 and H1N2 viruses can be expected to offer resistance to adamantane derivatives, but not to neuraminidase inhibitors.

  7. Genetic Characterization of H1N1 and H1N2 Influenza A Viruses Circulating in Ontario Pigs in 2012.

    Directory of Open Access Journals (Sweden)

    Helena Grgić

    Full Text Available The objective of this study was to characterize H1N1 and H1N2 influenza A virus isolates detected during outbreaks of respiratory disease in pig herds in Ontario (Canada in 2012. Six influenza viruses were included in analysis using full genome sequencing based on the 454 platform. In five H1N1 isolates, all eight segments were genetically related to 2009 pandemic virus (A(H1N1pdm09. One H1N2 isolate had hemagglutinin (HA, polymerase A (PA and non-structural (NS genes closely related to A(H1N1pdm09, and neuraminidase (NA, matrix (M, polymerase B1 (PB1, polymerase B2 (PB2, and nucleoprotein (NP genes originating from a triple-reassortant H3N2 virus (tr H3N2. The HA gene of five Ontario H1 isolates exhibited high identity of 99% with the human A(H1N1pdm09 [A/Mexico/InDRE4487/09] from Mexico, while one Ontario H1N1 isolate had only 96.9% identity with this Mexican virus. Each of the five Ontario H1N1 viruses had between one and four amino acid (aa changes within five antigenic sites, while one Ontario H1N2 virus had two aa changes within two antigenic sites. Such aa changes in antigenic sites could have an effect on antibody recognition and ultimately have implications for immunization practices. According to aa sequence analysis of the M2 protein, Ontario H1N1 and H1N2 viruses can be expected to offer resistance to adamantane derivatives, but not to neuraminidase inhibitors.

  8. In vitro reassortment between endemic H1N2 and 2009 H1N1 pandemic swine influenza viruses generates attenuated viruses.

    Directory of Open Access Journals (Sweden)

    Ben M Hause

    Full Text Available The pandemic H1N1 (pH1N1 influenza virus was first reported in humans in the spring of 2009 and soon thereafter was identified in numerous species, including swine. Reassortant viruses, presumably arising from the co-infection of pH1N1 and endemic swine influenza virus (SIV, were subsequently identified from diagnostic samples collected from swine. In this study, co-infection of swine testicle (ST cells with swine-derived endemic H1N2 (MN745 and pH1N1 (MN432 yielded two reassortant H1N2 viruses (R1 and R2, both possessing a matrix gene derived from pH1N1. In ST cells, the reassortant viruses had growth kinetics similar to the parental H1N2 virus and reached titers approximately 2 log(10 TCID(50/mL higher than the pH1N1 virus, while in A549 cells these viruses had similar growth kinetics. Intranasal challenge of pigs with H1N2, pH1N1, R1 or R2 found that all viruses were capable of infecting and transmitting between direct contact pigs as measured by real time reverse transcription PCR of nasal swabs. Lung samples were also PCR-positive for all challenge groups and influenza-associated microscopic lesions were detected by histology. Interestingly, infectious virus was detected in lung samples for pigs challenged with the parental H1N2 and pH1N1 at levels significantly higher than either reassortant virus despite similar levels of viral RNA. Results of our experiment suggested that the reassortant viruses generated through in vitro cell culture system were attenuated without gaining any selective growth advantage in pigs over the parental lineages. Thus, reassortant influenza viruses described in this study may provide a good system to study genetic basis of the attenuation and its mechanism.

  9. Seroprevalence of H1N1, H3N2 and H1N2 influenza viruses in pigs in seven European countries in 2002-2003.

    Science.gov (United States)

    Van Reeth, Kristien; Brown, Ian H; Dürrwald, Ralf; Foni, Emanuela; Labarque, Geoffrey; Lenihan, Patrick; Maldonado, Jaime; Markowska-Daniel, Iwona; Pensaert, Maurice; Pospisil, Zdenek; Koch, Guus

    2008-05-01

    Avian-like H1N1 and human-like H3N2 swine influenza viruses (SIV) have been considered widespread among pigs in Western Europe since the 1980s, and a novel H1N2 reassortant with a human-like H1 emerged in the mid 1990s. This study, which was part of the EC-funded 'European Surveillance Network for Influenza in Pigs 1', aimed to determine the seroprevalence of the H1N2 virus in different European regions and to compare the relative prevalences of each SIV between regions. Laboratories from Belgium, the Czech Republic, Germany, Italy, Ireland, Poland and Spain participated in an international serosurvey. A total of 4190 sow sera from 651 farms were collected in 2002-2003 and examined in haemagglutination inhibition tests against H1N1, H3N2 and H1N2. In Belgium, Germany, Italy and Spain seroprevalence rates to each of the three SIV subtypes were high (> or =30% of the sows seropositive) to very high (> or =50%), except for a lower H1N2 seroprevalence rate in Italy (13.8%). Most sows in these countries with high pig populations had antibodies to two or three subtypes. In Ireland, the Czech Republic and Poland, where swine farming is less intensive, H1N1 was the dominant subtype (8.0-11.7% seropositives) and H1N2 and H3N2 antibodies were rare (0-4.2% seropositives). Thus, SIV of H1N1, H3N2 and H1N2 subtype are enzootic in swine producing regions of Western Europe. In Central Europe, SIV activity is low and the circulation of H3N2 and H1N2 remains to be confirmed. The evolution and epidemiology of SIV throughout Europe is being further monitored through a second 'European Surveillance Network for Influenza in Pigs'.

  10. Seroprevalence of H1N1, H3N2 and H1N2 influenza viruses in pigs in seven European countries in 2002-2003

    NARCIS (Netherlands)

    Reeth, K.; Brown, I.H.; Durrwald, R.; Foni, E.; Labarque, G.; Lenihan, P.; Maldonado, J.; Markowska-Daniel, I.; Pensaert, M.; Pospisil, Z.; Koch, G.

    2008-01-01

    Objectives Avian-like H1N1 and human-like H3N2 swine influenza viruses (SIV) have been considered widespread among pigs in Western Europe since the 1980s, and a novel H1N2 reassortant with a human-like H1 emerged in the mid 1990s. This study, which was part of the EC-funded 'European Surveillance

  11. Novel reassortant influenza A(H1N2) virus derived from A(H1N1)pdm09 virus isolated from swine, Japan, 2012.

    Science.gov (United States)

    Kobayashi, Miho; Takayama, Ikuyo; Kageyama, Tsutomu; Tsukagoshi, Hiroyuki; Saitoh, Mika; Ishioka, Taisei; Yokota, Yoko; Kimura, Hirokazu; Tashiro, Masato; Kozawa, Kunihisa

    2013-12-01

    We isolated a novel influenza virus A(H1N2) strain from a pig on January 13, 2012, in Gunma Prefecture, Japan. Phylogenetic analysis showed that the strain was a novel type of double-reassortant virus derived from the swine influenza virus strains H1N1pdm09 and H1N2, which were prevalent in Gunma at that time.

  12. Regioselectivity in the Thermal Rearrangement of Unsymmetrical 4-Methyl-4H-1,2,4-triazoles to 1-Methyl-1H-1,2,4-triazoles

    Directory of Open Access Journals (Sweden)

    Per H.J. Carlsen

    2001-11-01

    Full Text Available The rearrangement of 4-methyl-3,5-diaryl-4H-1,2,4-triazoles to the corresponding 1-methyl-3,5-diaryl-1H-1,2,4-triazoles showed regioselectivity comparable to that observed for the alkylation of 3,5-diaryl-1H-1,2,4-triazoles. This lends support to a proposed mechanism for the rearrangement that involves consecutive nucleophilic displacements steps.

  13. Characterization of Si detectors, search for vertex and potentiality of detecting a light charged Higgs boson in the CMS experiment; Caracterisation des detecteurs silicium, recherche de Vertex et etude du potentiel de decouverte d'un boson de Higgs charge leger dans l'experience CMS

    Energy Technology Data Exchange (ETDEWEB)

    Estre, N

    2004-07-01

    The CMS (compact muon solenoid) detector that will be set on the future LHC (large hadron collider) accelerator will enable us to continue our search for the Higgs boson as well as to look for any hint for a new physics beyond the standard model. CMS is composed of an efficient muon detector, an electromagnetic calorimeter and of a tracker with high spatial resolution, this tracker is the topic of this thesis. The tracker will allow an accurate reconstruction of charged-particles trajectories and the reconstruction of the primary interaction vertex. The tracker's technology is based on micro-strip Si detectors, tests performed with the SPS particle beam show that these detectors have an impact reconstruction efficiency greater than 98% and a piling-up rate limited to 6%. The spatial resolution concerning particle trajectories is about 45 {mu}m for an interval of 183 {mu}m between 2 strips. The simulation for the search for a light charged Higgs boson show that an excess of {tau}{nu}{sub {tau}} + bb-bar + qq-bar' events is possible to be observed for any value of tan({beta}) up to M{sub A} = 122 GeV/c{sup 2} during the first year of operation and up to 136 GeV/c{sup 2} afterwards. With the assumption that this event excess is due to the decay of charged Higgs bosons we can state that the assessment of its mass will be possible till m{sub H} = 150 GeV/c{sup 2} with an accuracy of 15 GeV/c{sup 2}. (A.C.)

  14. Experimental infection with H1N1 European swine influenza virus protects pigs from an infection with the 2009 pandemic H1N1 human influenza virus.

    Science.gov (United States)

    Busquets, Núria; Segalés, Joaquim; Córdoba, Lorena; Mussá, Tufaria; Crisci, Elisa; Martín-Valls, Gerard E; Simon-Grifé, Meritxell; Pérez-Simó, Marta; Pérez-Maíllo, Monica; Núñez, Jose I; Abad, Francesc X; Fraile, Lorenzo; Pina, Sonia; Majó, Natalia; Bensaid, Albert; Domingo, Mariano; Montoya, María

    2010-01-01

    The recent pandemic caused by human influenza virus A(H1N1) 2009 contains ancestral gene segments from North American and Eurasian swine lineages as well as from avian and human influenza lineages. The emergence of this A(H1N1) 2009 poses a potential global threat for human health and the fact that it can infect other species, like pigs, favours a possible encounter with other influenza viruses circulating in swine herds. In Europe, H1N1, H1N2 and H3N2 subtypes of swine influenza virus currently have a high prevalence in commercial farms. To better assess the risk posed by the A(H1N1) 2009 in the actual situation of swine farms, we sought to analyze whether a previous infection with a circulating European avian-like swine A/Swine/Spain/53207/2004 (H1N1) influenza virus (hereafter referred to as SwH1N1) generated or not cross-protective immunity against a subsequent infection with the new human pandemic A/Catalonia/63/2009 (H1N1) influenza virus (hereafter referred to as pH1N1) 21 days apart. Pigs infected only with pH1N1 had mild to moderate pathological findings, consisting on broncho-interstitial pneumonia. However, pigs inoculated with SwH1N1 virus and subsequently infected with pH1N1 had very mild lung lesions, apparently attributed to the remaining lesions caused by SwH1N1 infection. These later pigs also exhibited boosted levels of specific antibodies. Finally, animals firstly infected with SwH1N1 virus and latter infected with pH1N1 exhibited undetectable viral RNA load in nasal swabs and lungs after challenge with pH1N1, indicating a cross-protective effect between both strains. © INRA, EDP Sciences, 2010.

  15. Characterization of a newly emerged genetic cluster of H1N1 and H1N2 swine influenza virus in the United States.

    Science.gov (United States)

    Vincent, Amy L; Ma, Wenjun; Lager, Kelly M; Gramer, Marie R; Richt, Juergen A; Janke, Bruce H

    2009-10-01

    H1 influenza A viruses that were distinct from the classical swine H1 lineage were identified in pigs in Canada in 2003–2004; antigenic and genetic characterization identified the hemagglutinin (HA) as human H1 lineage. The viruses identified in Canadian pigs were human lineage in entirety or double (human–swine) reassortants. Here, we report the whole genome sequence analysis of four human-like H1 viruses isolated from U.S. swine in 2005 and 2007. All four isolates were characterized as triple reassortants with an internal gene constellation similar to contemporary U.S. swine influenza virus (SIV), with HA and neuraminidase (NA) most similar to human influenza virus lineages. A 2007 human-like H1N1 was evaluated in a pathogenesis and transmission model and compared to a 2004 reassortant H1N1 SIV isolate with swine lineage HA and NA. The 2007 isolate induced disease typical of influenza virus and was transmitted to contact pigs; however, the kinetics and magnitude differed from the 2004 H1N1 SIV. This study indicates that the human-like H1 SIV can efficiently replicate and transmit in the swine host and now co-circulates with contemporary SIVs as a distinct genetic cluster of H1 SIV.

  16. Nouvelle initiative des chaires de recherche Canada-Afrique du Sud ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    8 déc. 2016 ... Elles s'appuient sur le South African Research Chairs Initiative (SARChl), ainsi que sur le programme de chaires de recherche industrielle, dont le financement provient en partie du Conseil de recherches en sciences naturelles et en génie du Canada (CRSNG) et du Programme des chaires de recherche ...

  17. Tirer des connaissances de la recherche locale et les utiliser aux ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    gs

    La Carnegie Corporation of New York (CCNY) et le Centre de recherches pour le développement international (CRDI) annoncent le lancement d'une initiative de recherche concertée intitulée Tirer des connaissances de la recherche locale et les utiliser aux fins de la consolidation de la paix et du renforcement de l'État.

  18. Search for excited leptons in the data of the H1 experiment at the HERA collider

    International Nuclear Information System (INIS)

    Delerue, N.

    2002-09-01

    Composite models are one of the possible extensions of the Standard Model. One of their implications, at the energy in the reach of present particles accelerators, would be the excitation of leptons. This PhD. thesis describes the search for excited leptons with the H1 detector installed on the electron-proton collider HERA in Hamburg (Germany). The data used were accumulated between 1994 and 2000 and amount to an integrated luminosity of 120 pb -1 . The analysis of 6 different topologies were done and cover all the branching ratios of desexcitation of excited electron and neutrino. The numbers of candidates found during those analysis is in agreement with the Standard Model expectations. This means that no evidence of excited leptons production was found at HERA. This result was translated in the form of exclusion limits on the coupling of excited leptons (f/A) depending on the mass of the excited lepton. For the first time at HERA we addressed the case were the natural decay width of the excited neutrino is wider than the experimental resolution. For the first time also, a study of the variation of limit depending on the ratio f' / f was carried out. This study lead to the setting of limits independent of this ratio. The limits obtained extend results previously obtained at HERA and also the results of direct searches at LEP. (orig.)

  19. KS0 production at high Q2 in deep inelastic ep scattering at H1

    International Nuclear Information System (INIS)

    Ruiz Tabasco, Julia Elizabeth

    2010-12-01

    The production of K S 0 mesons is studied using deep-inelastic scattering events (DIS) recorded with the H1 detector at the HERA ep collider. The measurements are performed in the phase space defined by the four-momentum transfer squared of the photon, 145 GeV 2 2 . The differential production cross sections of the K S 0 meson are presented as function of the kinematic variables Q 2 and x, the transverse momentum p T and the pseudorapidity η of the particle in laboratory frame, and as function of the momentum fraction x p BF and transverse momentum p T BF in the Breit Frame. Moreover, the K S 0 production rate is compared to the production of charged particles and to the production of DIS events in the same region of phase space. The data are compared to theoretical predictions, based on leading order Monte Carlo programs with matched parton showers. The Monte Carlo models are also used for studies of the flavour contribution to the K S 0 production and parton density function dependence. (orig.)

  20. Cryogenic detectors

    International Nuclear Information System (INIS)

    Zehnder, A.

    1987-01-01

    Presently the development of new large scale detector systems, used in very high energy physics experiments, is very active. In the low energy range, the introduction of charge coupled devices allows improved spacial and energy resolution. In the keV region, high resolution can only be achieved via the well established diffraction spectrometers with the well-known disadvantage of a small throughput. There exist no efficient detectors for non-ionizing radiation such as coherent nuclear scattering of weakly interacting particles. The development of high resolution solid state detectors in the keV-region with the possibility of nuclear recoil detection is therefore highly desired. Such detectors applied in astro and particle physics would thus allow one to obtain new information not achievable otherwise. Three types of cryogenic detectors exist: Calorimeters/Bolometers. This type is sensitive to the produced excess phonons and measures the deposited energy by detecting the heat pulses. Excess charge carriers should be used to produce phonons. Tunneling junctions. This type is sensitive to excess charge produced by the Cooper pair breakup. Excess phonons should be used to break up Cooper pairs. Superheated superconducting granules (SSG). An SSG detector consists of granules, the metastability of which is disturbed by radiation. The Meissner effect then causes a change in the field distribution of the applied external field, which can be detected. The present paper discusses the basic principle of calorimetric and tunneling junction detectors and some of their applications. 26 refs., 7 figs., 1 tab

  1. Detectors - Electronics

    International Nuclear Information System (INIS)

    Bregeault, J.; Gabriel, J.L.; Hierle, G.; Lebotlan, P.; Leconte, A.; Lelandais, J.; Mosrin, P.; Munsch, P.; Saur, H.; Tillier, J.

    1998-01-01

    The reports presents the main results obtained in the fields of radiation detectors and associated electronics. In the domain of X-ray gas detectors for the keV range efforts were undertaken to rise the detector efficiency. Multiple gap parallel plate chambers of different types as well as different types of X → e - converters were tested to improve the efficiency (values of 2.4% at 60 KeV were reached). In the field of scintillators a study of new crystals has been carried out (among which Lutetium orthosilicate). CdTe diode strips for obtaining X-ray imaging were studied. The complete study of a linear array of 8 CdTe pixels has been performed and certified. The results are encouraging and point to this method as a satisfying solution. Also, a large dimension programmable chamber was used to study the influence of temperature on the inorganic scintillators in an interval from -40 deg. C to +150 deg. C. Temperature effects on other detectors and electronic circuits were also investigated. In the report mentioned is also the work carried out for the realization of the DEMON neutron multidetector. For neutron halo experiments different large area Si detectors associated with solid and gas position detectors were realized. In the frame of a contract with COGEMA a systematic study of Li doped glasses was undertaken aiming at replacing with a neutron probe the 3 He counters presently utilized in pollution monitoring. An industrial prototype has been realised. Other studies were related to integrated analog chains, materials for Cherenkov detectors, scintillation probes for experiments on fundamental processes, gas position sensitive detectors, etc. In the field of associated electronics there are mentioned the works related to the multidetector INDRA, data acquisition, software gamma spectrometry, automatic gas pressure regulation in detectors, etc

  2. Hydrogen detector

    International Nuclear Information System (INIS)

    Kumagaya, Hiromichi; Yoshida, Kazuo; Sanada, Kazuo; Chigira, Sadao.

    1994-01-01

    The present invention concerns a hydrogen detector for detecting water-sodium reaction. The hydrogen detector comprises a sensor portion having coiled optical fibers and detects hydrogen on the basis of the increase of light transmission loss upon hydrogen absorption. In the hydrogen detector, optical fibers are wound around and welded to the outer circumference of a quartz rod, as well as the thickness of the clad layer of the optical fiber is reduced by etching. With such procedures, size of the hydrogen detecting sensor portion can be decreased easily. Further, since it can be used at high temperature, diffusion rate is improved to shorten the detection time. (N.H.)

  3. 20 CFR 655.705 - What Federal agencies are involved in the H-1B and H-1B1 programs, and what are the...

    Science.gov (United States)

    2010-04-01

    ... Employers Seeking To Employ Nonimmigrants on H-1b Visas in Specialty Occupations and as Fashion Models, and... whether the individual is a fashion model of distinguished merit and ability, and whether the... § 655.700(d)(4). Each employer seeking an H-1B nonimmigrant in a specialty occupation or as a fashion...

  4. Antigenic variation of H1N1, H1N2 and H3N2 swine influenza viruses in Japan and Vietnam.

    Science.gov (United States)

    Takemae, Nobuhiro; Nguyen, Tung; Ngo, Long Thanh; Hiromoto, Yasuaki; Uchida, Yuko; Pham, Vu Phong; Kageyama, Tsutomu; Kasuo, Shizuko; Shimada, Shinichi; Yamashita, Yasutaka; Goto, Kaoru; Kubo, Hideyuki; Le, Vu Tri; Van Vo, Hung; Do, Hoa Thi; Nguyen, Dang Hoang; Hayashi, Tsuyoshi; Matsuu, Aya; Saito, Takehiko

    2013-04-01

    The antigenicity of the influenza A virus hemagglutinin is responsible for vaccine efficacy in protecting pigs against swine influenza virus (SIV) infection. However, the antigenicity of SIV strains currently circulating in Japan and Vietnam has not been well characterized. We examined the antigenicity of classical H1 SIVs, pandemic A(H1N1)2009 (A(H1N1)pdm09) viruses, and seasonal human-lineage SIVs isolated in Japan and Vietnam. A hemagglutination inhibition (HI) assay was used to determine antigenic differences that differentiate the recent Japanese H1N2 and H3N2 SIVs from the H1N1 and H3N2 domestic vaccine strains. Minor antigenic variation between pig A(H1N1)pdm09 viruses was evident by HI assay using 13 mAbs raised against homologous virus. A Vietnamese H1N2 SIV, whose H1 gene originated from a human strain in the mid-2000s, reacted poorly with post-infection ferret serum against human vaccine strains from 2000-2010. These results provide useful information for selection of optimal strains for SIV vaccine production.

  5. Search for non-baryonic dark matter with cryogenic detectors based on ionisation and heat detection. Analysis of experimental data from the Edelweiss-I experiment; Recherche de la matiere noire non-baryonique a l'aide de detecteurs cryogeniques a double composante ionisation et chaleur: Analyse et Interpretation des donnees de l'experience EDELWEISS-I

    Energy Technology Data Exchange (ETDEWEB)

    Sanglard, V

    2005-11-15

    The method of direct detection of WIMPs (weakly interactive massive particles) that are present in the halo of our galaxy rests on the detection of their interaction with a target nucleus. The Edelweiss experiment uses this technique with 3 cryogenic detectors operating on 2 modes ionization and heat. Each detector is made of a 320 g germanium crystal with 2 faces equipped with electrodes. In order to improve the collection of charges, an amorphous layer of Ge or Si is laid between the crystal surface and the electrodes. The validation of the detector system has been made with Co{sup 57} and Cs{sup 137} gamma sources and a Cf{sup 252} neutron source. We present a comparison with simulation results and experimental data for the validation of the response to nuclear recoils. The whole experimental data collected by Edelweiss-I from 2000 till 2003 has been analysed. 40 events have been selected, 6 among them with an energy over 30 keV. Limits for the interaction cross-section between a WIMP and a nucleon have been deduced from the experimental data. The Yellin method has enabled us to determine a limit without knowing the background noise. The best sensitivity appears to be 1.5*10{sup -6} pb for a WIMP's mass of 80 GeV/c{sup 2} and a confidence level of 90 per cent. In terms of events, the limit for an energy range of 30 - 100 keV is 0.12 events per kg and per day. (A.C.)

  6. Résultats de recherche | Page 85 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Amélioration de la santé des mères et des enfants dans les régions rurales mal desservies du Nigeria grâce à la recherche visant la mise en oeuvre. La santé des mères et des enfants est une priorité pour le Nigeria, mais d'importants défis et possibilités à l'échelon des États influencent les efforts déployés pour réduire les ...

  7. Résultats de recherche | Page 15 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Étude des soins de santé primaires dispensés dans les pays du cône Sud. Les pays membres du Réseau de recherche sur les systèmes et services de santé dans les pays du cône Sud (Red de Investigación en Sistemas y Servicios de Salud en el Cono Sur) ont des systèmes de santé considérablement segmentés et ...

  8. Résultats de recherche | Page 29 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Étude des soins de santé primaires dispensés dans les pays du cône Sud. Les pays membres du Réseau de recherche sur les systèmes et services de santé dans les pays du cône Sud (Red de Investigación en Sistemas y Servicios de Salud en el Cono Sur) ont des systèmes de santé considérablement segmentés et ...

  9. Résultats de recherche | Page 147 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Étude des soins de santé primaires dispensés dans les pays du cône Sud. Les pays membres du Réseau de recherche sur les systèmes et services de santé dans les pays du cône Sud (Red de Investigación en Sistemas y Servicios de Salud en el Cono Sur) ont des systèmes de santé considérablement segmentés et ...

  10. Résultats de recherche | Page 26 | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Après la rupture d'un grand barrage au sud-est du Brésil, des déchets métalliques et de boue contaminèrent l'eau et causèrent la pire catastrophe écologique de l'histoire de la nation. La recherche d'Adalto Bianchini aide son pays à réviser sa règlementation relative à une de ses ressources les plus précieuses. Date de ...

  11. Résultats de recherche | Page 2 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    L'accès équitable à l'eau et la gestion efficace de l'eau sont des éléments essentiels au développement durable, à la protection des écosystèmes et à la ... Les pays membres du Réseau de recherche sur les systèmes et services de santé dans les pays du cône Sud (Red de Investigación en Sistemas y Servicios de Salud ...

  12. Résultats de recherche | Page 6 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Programme de bourse de recherche sur les questions touchant la sécurité, les stupéfiants et la démocratie en Amérique latine et dans les Caraïbes. Cette subvention soutiendra un programme de bourses et d'ateliers sur les liens entre la sécurité, le crime organisé, les stupéfiants et la démocratie en Amérique latine et ...

  13. Résultats de recherche | Page 8 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Élites, crime organisé, violence et érosion de l'État en Colombie, au Guatemala, au Honduras et au Nicaragua. En dépit d'un consensus sur le fait que le crime organisé en Amérique latine prend de l'ampleur et prolifère sur le plan géographique, peu de travaux de recherche s'intéressent à l'incidence du crime organisé ...

  14. H1DS: A new web-based data access system

    Energy Technology Data Exchange (ETDEWEB)

    Pretty, D.G., E-mail: david.pretty@anu.edu.au; Blackwell, B.D.

    2014-05-15

    Highlights: • We present H1DS, a new RESTful web service for accessing fusion data. • We examine the scalability and extensibility of H1DS. • We present a fast and user friendly web browser client for the H1DS web service. • A summary relational database is presented as an application of the H1DS API. - Abstract: A new data access system, H1DS, has been developed and deployed for the H-1 Heliac at the Australian Plasma Fusion Research Facility. The data system provides access to fusion data via a RESTful web service. With the URL acting as the API to the data system, H1DS provides a scalable and extensible framework which is intuitive to new users, and allows access from any internet connected device. The H1DS framework, originally designed to work with MDSplus, has a modular design which can be extended to provide access to alternative data storage systems.

  15. H1DS: A new web-based data access system

    International Nuclear Information System (INIS)

    Pretty, D.G.; Blackwell, B.D.

    2014-01-01

    Highlights: • We present H1DS, a new RESTful web service for accessing fusion data. • We examine the scalability and extensibility of H1DS. • We present a fast and user friendly web browser client for the H1DS web service. • A summary relational database is presented as an application of the H1DS API. - Abstract: A new data access system, H1DS, has been developed and deployed for the H-1 Heliac at the Australian Plasma Fusion Research Facility. The data system provides access to fusion data via a RESTful web service. With the URL acting as the API to the data system, H1DS provides a scalable and extensible framework which is intuitive to new users, and allows access from any internet connected device. The H1DS framework, originally designed to work with MDSplus, has a modular design which can be extended to provide access to alternative data storage systems

  16. Study of hadrons energy resolution in a liquid argon calorimeter for the H1 experiment and study of supersymmetric particles detection at Hera

    International Nuclear Information System (INIS)

    Besancon, M.

    1989-08-01

    Tests of liquid Argon calorimeters have been carried out at CERN in 1986 and 1987 in order to study the properties of the forthcoming H1 detector calorimeter installed at the HERA collider. In the first part of this work, from data analysis, several weighting methods of the measured charge for hadronic showers are proposed and discussed. These weighting methods allow to correct the non compensation of liquid Argon calorimeters and so to optimize the hadrons energy resolution. The problem of electrons and pions identification is also met. In the second part, selectron and squark production is considered in the electrons protons collisions of HERA. Signal extraction from standard background is studied with the help of a simulation of supersymmetric and deep inelastic scattering processes as well as a rough simulation of the H1 detector [fr

  17. DUMAND detector

    CERN Multimedia

    This object is one of the 256 other detectors of the DUMAND (Deep Underwater Muon And Neutrino Detection) experiment. The goal of the experiment was the construction of the first deep ocean high energy neutrino detector, to be placed at 4800 m depth in the Pacific Ocean off Keahole Point on the Big Island of Hawaii. A few years ago, a European conference with Cosmic experiments was organized at CERN as they were projects like DUMAND in Hawaii. Along with the conference, a temporary exhibition was organised as well. It was a collaboration of institutions from Germany, Japan, Switzerland and the U.S.A. CERN had borrowed equipment and objects from different institutes around the world, including this detector of the DUMAND experiment. Most of the equipment were sent back to the institutes, however this detector sphere was offered to a CERN member of the personnel.

  18. Detector applications

    International Nuclear Information System (INIS)

    Pehl, R.H.

    1977-10-01

    Semiconductor detectors are now applied to a very wide range of problems. The combination of relatively low cost, excellent energy resolution, and simultaneous broad energy-spectrum analysis is uniquely suited to many applications in both basic and applied physics. Alternative techniques, such as magnetic spectrometers for charged-particle spectroscopy, while offering better energy resolution, are bulky, expensive, and usually far more difficult to use. Furthermore, they do not directly provide the broad energy-spectrum measurements easily accomplished using semiconductor detectors. Scintillation detectors, which are approximately equivalent to semiconductor detectors in convenience and cost, exhibit 10 to 100 times worse energy resolution. However, their high efficiency and large potential size recommend their use in some measurements

  19. Isolation and genetic characterization of avian-like H1N1 and novel ressortant H1N2 influenza viruses from pigs in China.

    Science.gov (United States)

    Yu, Hai; Zhang, Peng-Chao; Zhou, Yan-Jun; Li, Guo-Xin; Pan, Jie; Yan, Li-Ping; Shi, Xiao-Xiao; Liu, Hui-Li; Tong, Guang-Zhi

    2009-08-21

    As pigs are susceptible to both human and avian influenza viruses, they have been proposed to be intermediate hosts or mixing vessels for the generation of pandemic influenza viruses through reassortment or adaptation to the mammalian host. In this study, we reported avian-like H1N1 and novel ressortant H1N2 influenza viruses from pigs in China. Homology and phylogenetic analyses showed that the H1N1 virus (A/swine/Zhejiang/1/07) was closely to avian-like H1N1 viruses and seemed to be derived from the European swine H1N1 viruses, which was for the first time reported in China; and the two H1N2 viruses (A/swine/Shanghai/1/07 and A/swine/Guangxi/13/06) were novel ressortant H1N2 influenza viruses containing genes from the classical swine (HA, NP, M and NS), human (NA and PB1) and avian (PB2 and PA) lineages, which indicted that the reassortment among human, avian, and swine influenza viruses had taken place in pigs in China and resulted in the generation of new viruses. The isolation of avian-like H1N1 influenza virus originated from the European swine H1N1 viruses, especially the emergence of two novel ressortant H1N2 influenza viruses provides further evidence that pigs serve as intermediate hosts or "mixing vessels", and swine influenza virus surveillance in China should be given a high priority.

  20. Syntheses and modulations in the chromatin contents of histones H1/sup o/ and H1 during G1 and S phases in Chinese hamsters cells

    International Nuclear Information System (INIS)

    D'Anna, J.A.; Gurley, L.R.; Tobey, R.A.

    1982-01-01

    Flow cytometry, conventional autoradiography, and autoradiography employing high concentrations of high specific activity [ 3 H]thymidine indicate that (1) treatment of Chinese hamster ovary (line CHO) cells with butyrate truly blocks cells in G 1 and (2) cells blocked in G 1 by isoleucine deprivation remain blocked in G 1 when they are released into complete medium containing butyrate. Measurements of H1/sup o/ content relative to core histones and H1/sup o/:H1 ratios indicate that H1/sup o/ is enhanced somewhat in G 1 cells arrested by isoleucine deprivation; however, (1) treatment with butyrate greatly increases the H1/sup o/ content in G 1 -blocked cells, and (2) the enhancement is very sensitive to butyrate concentration. Measurements of relative histone contents in the isolated chromatin of synchronized cultures also suggest that the acid-soluble content of histone H1 (relative to core histones) becomes greatly depleted in the isolated chromatin when synchronized cells are blocked in early S phase by sequential use of isoleucine deprivation and hydroxyurea blockade. We also have measured [ 3 H]lysine incorporation, various protein ratios, and relative rates of deposition of newly synthesized H1/sup o/, H1, and H4 onto chromatin during G 1 and S in the absence of butyrate. The results suggest a dynamic picture of chromatin organization in which (1) newly synthesized histone H1/sup o/ binds to chromatin during traverse of G 1 and S phases and (2) histone H1 dissociates from (or becomes loosely bound to) chromatin during prolonged early S-phase block with hydroxyurea

  1. Smoke detectors

    International Nuclear Information System (INIS)

    Bryant, J.; Howes, J.H.; Smout, D.W.S.

    1979-01-01

    A smoke detector is described which provides a smoke sensing detector and an indicating device and in which a radioactive substance is used in conjunction with two ionisation chambers. The system includes an outer electrode, a collector electrode and an inner electrode which is made of or supports the radioactive substance which, in this case, is 241 Am. The invention takes advantage of the fact that smoke particles can be allowed to enter freely the inner ionisation chamber. (U.K.)

  2. Radiation detector

    International Nuclear Information System (INIS)

    Gillies, W.

    1980-01-01

    The radiation detector for measuring e.g. a neutron flux consists of a central emitter, an insulating shell arranged around it, and a tube-shaped collector enclosing both. The emitter itself is composed of a great number of stranded, spiral wires of small diameter giving a defined flexibility to the detector. For emitter material Pt, Rh, V, Co, Ce, Os or Ta may be used. (DG) [de

  3. Split detector

    International Nuclear Information System (INIS)

    Cederstrand, C.N.; Chism, H.R.

    1982-01-01

    A gas analyzer is disclosed which provides a dual channel capability for the simultaneous determination of the presence and concentration of two gases in a stream of sample gas and which has a single infrared source, a single sample cell, two infrared bandpass filters, and two infrared detectors. A separator between the filters and detectors prevents interchange of radiation between the filters. The separator is positioned by fitting it in a slot

  4. 26 CFR 1.1402(h)-1 - Members of certain religious groups opposed to insurance.

    Science.gov (United States)

    2010-04-01

    ... insurance. 1.1402(h)-1 Section 1.1402(h)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Tax on Self-Employment Income § 1.1402(h)-1... 1402(h) and this section refer does not include liability insurance of a kind that provides only for...

  5. 26 CFR 1.643(h)-1 - Distributions by certain foreign trusts through intermediaries.

    Science.gov (United States)

    2010-04-01

    ... intermediaries. 1.643(h)-1 Section 1.643(h)-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Estates, Trusts, and Beneficiaries § 1.643(h)-1... section, FT is deemed to have distributed XYZ stock with a value of 85X to C on December 1, 2001. (h...

  6. 76 FR 62455 - Announcement of Updated Funding Availability for H-1B Technical Skills Training Grants

    Science.gov (United States)

    2011-10-07

    ... 10-13] Announcement of Updated Funding Availability for H-1B Technical Skills Training Grants AGENCY... the availability of $240 million for the H-1B Technical Skills Training Grants to be awarded through a... additional applicants to apply for the H-1B Technical Skills Training Grants competition that will close on...

  7. Factors Influencing School Closure and Dismissal Decisions: Influenza A (H1N1), Michigan 2009

    Science.gov (United States)

    Dooyema, Carrie A.; Copeland, Daphne; Sinclair, Julie R.; Shi, Jianrong; Wilkins, Melinda; Wells, Eden; Collins, Jim

    2014-01-01

    Background: In fall 2009, many US communities experienced school closures during the influenza A H1N1 pandemic (pH1N1) and the state of Michigan reported 567 closures. We conducted an investigation in Michigan to describe pH1N1-related school policies, practices, and identify factors related to school closures. Methods: We distributed an online…

  8. Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States.

    Science.gov (United States)

    Rajao, Daniela S; Anderson, Tavis K; Kitikoon, Pravina; Stratton, Jered; Lewis, Nicola S; Vincent, Amy L

    2018-05-01

    Several lineages of influenza A viruses (IAV) currently circulate in North American pigs. Genetic diversity is further increased by transmission of IAV between swine and humans and subsequent evolution. Here, we characterized the genetic and antigenic evolution of contemporary swine H1N1 and H1N2 viruses representing clusters H1-α (1A.1), H1-β (1A.2), H1pdm (1A.3.3.2), H1-γ (1A.3.3.3), H1-δ1 (1B.2.2), and H1-δ2 (1B.2.1) currently circulating in pigs in the United States. The δ1-viruses diversified into two new genetic clades, H1-δ1a (1B.2.2.1) and H1-δ1b (1B.2.2.2), which were also antigenically distinct from the earlier H1-δ1-viruses. Further characterization revealed that a few key amino acid changes were associated with antigenic divergence in these groups. The continued genetic and antigenic evolution of contemporary H1 viruses might lead to loss of vaccine cross-protection that could lead to significant economic impact to the swine industry, and represents a challenge to public health initiatives that attempt to minimize swine-to-human IAV transmission. Published by Elsevier Inc.

  9. Data of evolutionary structure change: 1CR9H-1RUPH [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1CR9H-1RUPH 1CR9 1RUP H H KVKLQQSGAELVRSGASVKLSCTASGFNIKDY-YIQWVK...ine> TYR CA 299 TRP CA 347 1RUP... H 1RUPH YCAGLLWYDGGAGS...2550649642944336 1 1RUP H 1RUPH GYINY-SGFTS

  10. Study of charm and beauty production at HERA/H1 using dilepton events

    International Nuclear Information System (INIS)

    Goettlich, M.

    2007-04-01

    A measurement is presented which investigates the production of charm and beauty quarks in ep collisions at a centre-of-mass energy of 318 GeV. Data taken by the H1 detector at the HERA collider in the years 1999, 2000, 2004 and 2005 are analysed. The collected data correspond to an integrated luminosity of 221.6 pb -1 . This is the rst measurement of charm and beauty cross sections using HERA II data. Events with two or more jets of transverse momentum p t >5(4) GeV in the polar angular range 20 t >2(1) GeV in the polar angular ranges 30 1 2 2 2 , and for inelasticities 0.1 t rel of the leptons with respect to the jet they are associated to and the charge and angle correlation of the leptons are exploited to extract the fractions of charm and beauty events on a statistical basis. For the first time at H1, visible charm and beauty cross sections for the production of dijet and dilepton events are determined: σ(ep→ec anti cX→ejjμeX ' )=4.6±1.0(stat.)±0.5(sys.) pb, σ(ep→ec anti cX→ejjμμX ' )=2.7 ±0.9(stat.)±0.3(sys.) pb, σ(ep→eb anti bX→ejjμeX ' )=9.4±1.2(stat.)±0.9(sys.) pb, and σ(ep →eb anti bX→ejjμμX ' )=10.4 ± 1.5(stat.) ± 1.0(sys.) pb. To gain a deeper understanding of dilepton correlations in beauty events, differential dilepton cross sections are determined using the observable p t rel alone. The invariant mass m(μl), the transverse momentum p t (μl), the polar angle θ(μl) and the charge and angle correlation vertical stroke Δφ(μ 1 ,l 2 ) vertical stroke x Q(μ 1 ) x Q(l 2 ) of the dilepton system are investigated. In addition, differential jet cross sections are determined. The measurements are compared with leading order QCD calculations, supplemented with parton showers. The charm cross sections are consistent with the predictions, while the predicted beauty cross sections are somewhat lower than the measurement. The predicted differential beauty cross sections describe the shape of the measurements. (orig.)

  11. Epigenetics and autism spectrum disorder: A report of an autism case with mutation in H1 linker histone HIST1H1e and literature review.

    Science.gov (United States)

    Duffney, Lara J; Valdez, Purnima; Tremblay, Martine W; Cao, Xinyu; Montgomery, Sarah; McConkie-Rosell, Allyn; Jiang, Yong-Hui

    2018-04-27

    Genetic mutations in genes encoding proteins involved in epigenetic machinery have been reported in individuals with autism spectrum disorder (ASD), intellectual disability, congenital heart disease, and other disorders. H1 histone linker protein, the basic component in nucleosome packaging and chromatin organization, has not been implicated in human disease until recently. We report a de novo deleterious mutation of histone cluster 1 H1 family member e (HIST1H1E; c.435dupC; p.Thr146Hisfs*50), encoding H1 histone linker protein H1.4, in a 10-year-old boy with autism and intellectual disability diagnosed through clinical whole exome sequencing. The c.435dupC at the 3' end of the mRNA leads to a frameshift and truncation of the positive charge in the carboxy-terminus of the protein. An expression study demonstrates the mutation leads to reduced protein expression, supporting haploinsufficiency of HIST1H1E protein and loss of function as an underlying mechanism of dysfunction in the brain. Taken together with other recent cases with mutations of HIST1H1E in intellectual disability, the evidence supporting the link to causality in disease is strong. Our finding implicates the deficiency of H1 linker histone protein in autism. The systematic review of candidate genes implicated in ASD revealed that 42 of 215 (19.5%) genes are directly involved in epigenetic regulations and the majority of these genes belong to histone writers, readers, and erasers. While the mechanism of how haploinsufficiency of HIST1H1E causes autism is entirely unknown, our report underscores the importance of further study of the function of this protein and other histone linker proteins in brain development. © 2018 Wiley Periodicals, Inc.

  12. G1- and S-phase syntheses of histones H1 and H1o in mitotically selected CHO cells: utilization of high-performance liquid chromatography

    International Nuclear Information System (INIS)

    D'Anna, J.A.; Thayer, M.M.; Tobey, R.A.; Gurley, L.R.

    1985-01-01

    The authors have employed high-performance liquid chromatography (HPLC) to investigate the syntheses of histones H1 and H1o as synchronized cells traverse from mitosis to S phase. Chinese hamster (line CHO) cells were synchronized by mitotic selection, and, at appropriate times, they were pulse labeled for 1 h with [ 3 H]lysine. Histones H1 and H1o were extracted by blending radiolabeled and carrier cells directly in 0.83 M HC1O 4 ; the total HC1O 4 -soluble, Cl 3 CCO 2 H-precipitable proteins were then separated by a modification of an HPLC system employing three mu Bondapak reversed-phase columns. These procedures (1) produce minimally perturbed populations of synchronized proliferating cells and (2) maximize the recovery of radiolabeled histones during isolation and analysis. Measurements of rates of synthesis indicate that the rate of H1 synthesis increases as cells traverse from early to mid G1; as cells enter S phase, the rate of H1 synthesis increases an additional congruent to 22-fold and is proportional to the number of S-phase cells. In contrast to H1, the rate of H1o synthesis is nearly constant throughout G1. As cells progress into S phase, the rate of H1o synthesis increases so that it also appears to be proportional to the number of S-phase cells. Except for the first 1-2 h after mitotic selection, these results are similar to those obtained when cells are synchronized in G1 with the isoleucine deprivation procedure

  13. Influenza A (H1N1) neuraminidase inhibitors from Vitis amurensis

    DEFF Research Database (Denmark)

    Nguyen, Ngoc Anh; Dao, Trong Tuan; Tung, Bui Thanh

    2011-01-01

    Recently, a novel H1N1 influenza A virus (H1N1/09 virus) was identified and considered a strong candidate for a novel influenza pandemic. As part of an ongoing anti-influenza screening programme on natural products, eight oligostilbenes were isolated as active principles from the methanol extract...... of Vitis amurensis. This manuscript reports the isolation, structural elucidation, and anti-viral activities of eight compounds on various neuraminidases from influenza A/PR/8/34 (H1N1), novel swine-origin influenza A (H1N1), and oseltamivir-resistant novel H1N1 (H274Y) expressed in 293T cells...

  14. Search for gluinos decaying into b-jets and transverse missing energy with the detector D0 at the Tevatron; Recherche de gluinos dans la topologie a jets de quarks b et energie transverse manquante avec le detecteur D0 au TeVatron

    Energy Technology Data Exchange (ETDEWEB)

    Millet, Th

    2007-05-15

    The standard model of particle physics is the model of reference to explain the subatomic phenomena. This theoretical model has been successful for about 35 years. Although it has never been directly refuted, it has some theoretical and experimental limitations at high energy. That is why several new theories are trying to propose some extensions for this model. The supersymmetry is a possible extension, which is appreciated for its theoretical neatness. The work, which is presented in this manuscript, is dedicated to the search for a supersymmetric signal. The main feature of this signal are the presence of 4 b-jets and the high transverse missing energy. This search have been performed with the Run II data collected with the D0 detector from April 2003 to March 2006 (1 fb{sup -1}). The signature of such a topology needs a good energy resolution for the jets and a precise measure of the transverse missing energy. Consequently, it is essential to understand the information given by the calorimeter which is one of the crucial parts of the detector for such a search. The presence of the b-jets in the final state implies a efficient b-tagging. The b-tagging is a discriminant variable for the signal with respect to the standard model background. The hadronic colliders like the Tevatron are characterized by a QCD cross section which is many orders of magnitude larger than the supersymmetric signal cross section. Therefore, it is important to find fast and efficient selection cuts based on the calorimeter at the trigger level. The most important part of my work before the signal search has been dedicated on the study and the design of the trigger conditions for the jets and transverse missing energy signals. (author)

  15. Search for Higgs bosons in 2 lepton events and validation of a background noise detector in the DELPHI experiment; Recherche de bosons de higgs neutres dans les evenements a deux leptons isoles a LEP2 et mise au point d'un detecteur de controle du bruit de fond dans l'experience DELPHI

    Energy Technology Data Exchange (ETDEWEB)

    Lethuillier, M. [CEA/Saclay, Dept. d' Astrophysique, de la Physique des Particules, de la Physique Nucleaire et de l' Instrumentation Associee (DAPNIA), 91 - Gif-sur-Yvette (France)]|[Paris-7 Univ., 75 (France)

    1999-04-01

    This thesis presents two studies made within the DELPHI experiment in the context of the energy rise of the LEP collider. The first study concerns the setting up of a silicon plate detector that allows a continuous measurement of the background generated by the beams, particularly synchrotron radiation, the intensity of which increases strongly with the beam energy. This silicon monitor ensures a better safety of the more fragile DELPHI sub-detectors, especially the Time Projection Chamber, and gives a very precise measurement of the time of flight and energy of particles (2.1 ns and 3.6 keV resolution), thus allowing to identify the machine elements from which the background originates. The second study is devoted to the search for a neutral Higgs boson, produced in association with a Z boson decaying into an electron or a muon pair; we have searched for Higgs boson decays in b quarks, {tau} leptons or into invisible decay products as it is predicted by some supersymmetry scenarios. No signal has been observed in the 54 and 158 pb{sup -1} data recorded at {radical}s=183 and 189 GeV. Combining this result with those from other search channels, the hypothesis for a standard Higgs boson with a mass less than 94.5 GeV/c{sup 2} can be excluded at more than 95 % confidence level. In the frame of the Minimal Supersymmetric Model, this limit becomes 82.4 GeV/c{sup 2}, independently of the free parameter tan{beta}. Finally, as far as invisible decays are concerned, the limit becomes 90.2 GeV/c{sup 2}, independently of the branching ratio into invisible decay products. (author)

  16. Identification of reassortant pandemic H1N1 influenza virus in Korean pigs.

    Science.gov (United States)

    Han, Jae Yeon; Park, Sung Jun; Kim, Hye Kwon; Rho, Semi; Nguyen, Giap Van; Song, Daesub; Kang, Bo Kyu; Moon, Hyung Jun; Yeom, Min Joo; Park, Bong Kyun

    2012-05-01

    Since the 2009 pandemic human H1N1 influenza A virus emerged in April 2009, novel reassortant strains have been identified throughout the world. This paper describes the detection and isolation of reassortant strains associated with human pandemic influenza H1N1 and swine influenza H1N2 (SIV) viruses in swine populations in South Korea. Two influenza H1N2 reassortants were detected, and subtyped by PCR. The strains were isolated using Madin- Darby canine kidney (MDCK) cells, and genetically characterized by phylogenetic analysis for genetic diversity. They consisted of human, avian, and swine virus genes that were originated from the 2009 pandemic H1N1 virus and a neuraminidase (NA) gene from H1N2 SIV previously isolated in North America. This identification of reassortment events in swine farms raises concern that reassortant strains may continuously circulate within swine populations, calling for the further study and surveillance of pandemic H1N1 among swine.

  17. Shaped detector

    International Nuclear Information System (INIS)

    Carlson, R.W.

    1981-01-01

    A radiation detector or detector array which has a non-constant spatial response, is disclosed individually and in combination with a tomographic scanner. The detector has a first dimension which is oriented parallel to the plane of the scan circle in the scanner. Along the first dimension, the detector is most responsive to radiation received along a centered segment of the dimension and less responsive to radiation received along edge segments. This non-constant spatial response can be achieved in a detector comprised of a scintillation crystal and a photoelectric transducer. The scintillation crystal in one embodiment is composed of three crystals arranged in layers, with the center crystal having the greatest light conversion efficiency. In another embodiment, the crystal is covered with a reflective substance around the center segment and a less reflective substance around the remainder. In another embodiment, an optical coupling which transmits light from adjacent the center segment with the greatest intensity couples the scintillation crystal and the photoelectric transducer. In yet another embodiment, the photoelectric transducer comprises three photodiodes, one receiving light produced adjacent the central segment and the other two receiving light produced adjacent the edge segments. The outputs of the three photodiodes are combined with a differential amplifier

  18. Gamma multi-detectors and nuclear structure studies: search for superdeformed structures in {sup 147}Gd and {sup 144}Gd isotopes using Crystal Castle; simulation calculations for EUROGAM multi-detector definition; Multidetecteurs gamma et etudes de structure nucleaire: recherche avec le Chateau de Cristal de structures superdeformees dans les isotopes {sup 147}Gd et {sup 144}Gd; calculs de simulation pour la definition du multidetecteur EUROGAM

    Energy Technology Data Exchange (ETDEWEB)

    France, G de

    1992-12-31

    Computer simulations have been used for the calculation of the new generation of 4 {pi}{gamma} multi-detectors (Castle Crystal) of EUROGAM system (phase I and II). Two superdeformed bands (I and II), comprising 16 and 13 transitions respectively, have been described for {sup 147}Gd nucleus during the {sup 122}Sn({sup 30}Si,5n) fusion-evaporation reaction in a 155 MeV bombardment energy. Dynamic inertia momentum similarities and gamma transition energy similarities have been observed between band I and {sup 148}Gd nucleus and between band II and {sup 146}Gd nucleus, respectively. These similarities can be related to a pseudo-spin symmetry. Calculations suggest the existence of an octupolar susceptibility in this mass region. {sup 144}Gd nucleus has been studied using {sup 120}Sn({sup 29}Si,5n) fusion-evaporation reaction in a 155 MeV bombardment energy and using {sup 100}Mo({sup 48}Ti,4n) reactions in a 200 MeV bombardment energy. {gamma}-{gamma} coincidences have revealed the existence of a 58 keV width valley in the matrix representation compatible with theoretical predictions. In spite of the evidence for about ten transitions during these experiments, no superdeformed structure has been demonstrated for {sup 144}Gd nucleus. (J.S.). 87 refs., 57 figs., 41 tabs.

  19. Histone H1x is highly expressed in human neuroendocrine cells and tumours

    International Nuclear Information System (INIS)

    Warneboldt, Julia; Haller, Florian; Horstmann, Olaf; Danner, Bernhard C; Füzesi, László; Doenecke, Detlef; Happel, Nicole

    2008-01-01

    Histone H1x is a ubiquitously expressed member of the H1 histone family. H1 histones, also called linker histones, stabilize compact, higher order structures of chromatin. In addition to their role as structural proteins, they actively regulate gene expression and participate in chromatin-based processes like DNA replication and repair. The epigenetic contribution of H1 histones to these mechanisms makes it conceivable that they also take part in malignant transformation. Based on results of a Blast data base search which revealed an accumulation of expressed sequence tags (ESTs) of H1x in libraries from neuroendocrine tumours (NETs), we evaluated the expression of H1x in NETs from lung and the gastrointestinal tract using immunohistochemisty. Relative protein and mRNA levels of H1x were analysed by Western blot analysis and quantitative real-time RT-PCR, respectively. Since several reports describe a change of the expression level of the replacement subtype H1.0 during tumourigenesis, the analysis of this subtype was included in this study. We found an increased expression of H1x but not of H1.0 in NET tissues in comparison to corresponding normal tissues. Even though the analysed NETs were heterogenous regarding their grade of malignancy, all except one showed a considerably higher protein amount of H1x compared with corresponding non-neoplastic tissue. Furthermore, double-labelling of H1x and chromogranin A in sections of pancreas and small intestine revealed that H1x is highly expressed in neuroendocrine cells of these tissues. We conclude that the high expression of histone H1x in NETs is probably due to the abundance of this protein in the cells from which these tumours originate

  20. The N-terminal domain determines the affinity and specificity of H1 binding to chromatin

    International Nuclear Information System (INIS)

    Öberg, Christine; Belikov, Sergey

    2012-01-01

    Highlights: ► wt Human histone H1.4 and hH1.4 devoid of N-terminal domain, ΔN-hH1.4, were compared. ► Both histones bind to chromatin, however, ΔN-hH1.4 displays lower binding affinity. ► Interaction of ΔN-hH1.4 with chromatin includes a significant unspecific component. ► N-terminal domain is a determinant of specificity of histone H1 binding to chromatin. -- Abstract: Linker histone H1, one of the most abundant nuclear proteins in multicellular eukaryotes, is a key component of the chromatin structure mainly due to its role in the formation and maintenance of the 30 nm chromatin fiber. It has a three-domain structure; a central globular domain flanked by a short N-terminal domain and a long, highly basic C-terminal domain. Previous studies have shown that the binding abilities of H1 are at large determined by the properties of the C-terminal domain; much less attention has been paid to role of the N-terminal domain. We have previously shown that H1 can be reconstituted via cytoplasmic mRNA injection in Xenopus oocytes, cells that lack somatic H1. The heterologously expressed H1 proteins are incorporated into in vivo assembled chromatin at specific sites and the binding event is monitored as an increase in nucleosomal repeat length (NRL). Using this setup we have here compared the binding properties of wt-H1.4 and hH1.4 devoid of its N-terminal domain (ΔN-hH1.4). The ΔN-hH1.4 displays a drastically lower affinity for chromatin binding as compared to the wild type hH1.4. Our data also indicates that ΔN-hH1.4 is more prone to unspecific chromatin binding than the wild type. We conclude that the N-terminal domain of H1 is an important determinant of affinity and specificity of H1-chromatin interactions.

  1. A search for R-parity violating squark production with the H1 experiment at HERA

    Energy Technology Data Exchange (ETDEWEB)

    Herbst, Michael Clemens

    2011-12-15

    A search for R-parity violating supersymmetry is performed in the complete HERA data set taken at a centre-of-mass energy of {radical}(s)=319 GeV with the H1 detector. The integrated luminosity of the data sets corresponds to 255 pb{sup -1} of positron-proton, and 183 pb{sup -1} of electron-proton collision data. By introducing a lepton-quark-squark coupling {lambda}{sup '} the resonant production of single squarks is expected. Several exclusive selection channels, based on the topologies of final states expected from direct squark decays, and squark decays via gauginos are defined. The selection channels are based on an electron or a neutrino in the final state, and may contain further jets and leptons. All of the selection channels show a good agreement with the background expectation from standard model processes. The results are interpreted in terms of exclusion limits, obtained for the minimal supersymmetric standard model, and for the minimal supergravity model, constraining the strength of the R-parity violating couplings {lambda}{sub 1j1}{sup '} and {lambda}{sub 11k}{sup '}, and the supersymmetric model parameters, under the single coupling dominance hypothesis. For an R{sub p} coupling strength comparable to the electromagnetic coupling strength, {lambda}{sub 1j1}{sup '} or {lambda}{sub 11k}{sup '}={radical}(4{pi}{alpha}{sub em})=0.3, squark masses up to 275 GeV are excluded for u{sup j}{sub L} squarks, with d{sup k}{sub R} squarks further excluded up to 290 GeV, for all three squark generations j,k=1,2,3 at the 95% confidence level. (orig.)

  2. Charm and beauty production in D*μ events at H1/HERA

    International Nuclear Information System (INIS)

    Lucaci-Timoce, A.I.

    2007-07-01

    Charm and beauty photoproduction is investigated with the H1 detector at HERA using events with a reconstructed D * meson and a muon. Data taken during the years 1999-2000 and 2004-2006, corresponding to a total integrated luminosity of 320 pb -1 , are analysed. The D * mesons with transverse momentum p t (D * )>1.5 GeV and pseudorapidity vertical stroke η(D * ) vertical stroke *± →D (-)0 π s ± →(K -+ π ± )π s ± . In addition, muons with momentum p(μ)>2 GeV and vertical stroke η(μ) vertical stroke * meson and the muon. The charm and beauty cross sections were measured in photoproduction, i.e. for photon virtualities Q 2 2 , and for inelasticities 0.05 vis (ep→ec anti cX→eD *± μX)=314±33(stat)±101(syst)pb σ vis (ep→eb anti bX→eD *± μX)=90±20(stat)±26(syst)pb. The measurements are compared to leading order QCD calculations supplemented with parton showers as predicted by the PYTHIA Monte Carlo event generator. A ratio data/theory of 1.2±0.1(stat)±0.4(syst) and of 1.3±0.3(stat)±0.4(syst) is obtained for charm and beauty, respectively. Differential cross sections for the variables describing the D * μ system like transverse momentum p t (D * μ), pseudorapidity η(D * μ), invariant mass M(D * μ) and inelasticity y(D * μ) are measured and compared to the PYTHIA and the CASCADE Monte Carlo event generators. The theoretical models describe the shape of the differential distributions. Transverse momentum studies of the D * μ pair indicate a sensitivity to differing implementations of QCD dynamics in the simulation programs. (orig.)

  3. A search for R-parity violating squark production with the H1 experiment at HERA

    International Nuclear Information System (INIS)

    Herbst, Michael Clemens

    2011-12-01

    A search for R-parity violating supersymmetry is performed in the complete HERA data set taken at a centre-of-mass energy of √(s)=319 GeV with the H1 detector. The integrated luminosity of the data sets corresponds to 255 pb -1 of positron-proton, and 183 pb -1 of electron-proton collision data. By introducing a lepton-quark-squark coupling λ ' the resonant production of single squarks is expected. Several exclusive selection channels, based on the topologies of final states expected from direct squark decays, and squark decays via gauginos are defined. The selection channels are based on an electron or a neutrino in the final state, and may contain further jets and leptons. All of the selection channels show a good agreement with the background expectation from standard model processes. The results are interpreted in terms of exclusion limits, obtained for the minimal supersymmetric standard model, and for the minimal supergravity model, constraining the strength of the R-parity violating couplings λ 1j1 ' and λ 11k ' , and the supersymmetric model parameters, under the single coupling dominance hypothesis. For an R p coupling strength comparable to the electromagnetic coupling strength, λ 1j1 ' or λ 11k ' =√(4πα em )=0.3, squark masses up to 275 GeV are excluded for u j L squarks, with d k R squarks further excluded up to 290 GeV, for all three squark generations j,k=1,2,3 at the 95% confidence level. (orig.)

  4. Unpolarized neutral current e{sup {+-}}p cross section measurements at the H1 experiment, HERA

    Energy Technology Data Exchange (ETDEWEB)

    Habib, Shiraz Z.

    2009-11-15

    Measurements of the unpolarized inclusive neutral current reduced cross section in e{sup {+-}}p scattering at a center of mass energy {radical}(s) {approx_equal} 319 GeV are presented. The data was collected by the H1 detector during the HERA II running phase, after the 2000 luminosity upgrade, and corresponds to an integrated luminosity of 145 pb{sup -1} and 167 pb{sup -1} for the e{sup -}p and e{sup +}p periods respectively. The cross section measurements were made for the negative four-momentum transfer squared range 65{<=} Q{sup 2}{<=}30000 GeV{sup 2} and Bjorken-x range 0.00085{<=}x{<=}0.65. Dedicated measurements at inelasticity y=0.75 and Q{sup 2}{<=}800 GeV{sup 2} are also made. The details of the analysis are presented here. The cross section measurements presented here are found to agree with previously published data as well as predictions determined from various NLO QCD fits. Scaling violation of the F{sub 2} structure function as well differences between the e{sup -} and e{sup +} cross sections at high Q{sup 2} due to the xF{sub 3} structure function have been observed. The cross sections in the range Q{sup 2}{<=}800 GeV{sup 2} at inelasticity y=0.75 suggest non-zero values of the longitudinal structure function F{sub L}. (orig.)

  5. Effect of priming with H1N1 influenza viruses of variable antigenic distances on challenge with 2009 pandemic H1N1 virus.

    Science.gov (United States)

    O'Donnell, Christopher D; Wright, Amber; Vogel, Leatrice N; Wei, Chih-Jen; Nabel, Gary J; Subbarao, Kanta

    2012-08-01

    Compared to seasonal influenza viruses, the 2009 pandemic H1N1 (pH1N1) virus caused greater morbidity and mortality in children and young adults. People over 60 years of age showed a higher prevalence of cross-reactive pH1N1 antibodies, suggesting that they were previously exposed to an influenza virus or vaccine that was antigenically related to the pH1N1 virus. To define the basis for this cross-reactivity, ferrets were infected with H1N1 viruses of variable antigenic distance that circulated during different decades from the 1930s (Alaska/35), 1940s (Fort Monmouth/47), 1950s (Fort Warren/50), and 1990s (New Caledonia/99) and challenged with 2009 pH1N1 virus 6 weeks later. Ferrets primed with the homologous CA/09 or New Jersey/76 (NJ/76) virus served as a positive control, while the negative control was an influenza B virus that should not cross-protect against influenza A virus infection. Significant protection against challenge virus replication in the respiratory tract was observed in ferrets primed with AK/35, FM/47, and NJ/76; FW/50-primed ferrets showed reduced protection, and NC/99-primed ferrets were not protected. The hemagglutinins (HAs) of AK/35, FM/47, and FW/50 differ in the presence of glycosylation sites. We found that the loss of protective efficacy observed with FW/50 was associated with the presence of a specific glycosylation site. Our results suggest that changes in the HA occurred between 1947 and 1950, such that prior infection could no longer protect against 2009 pH1N1 infection. This provides a mechanistic understanding of the nature of serological cross-protection observed in people over 60 years of age during the 2009 H1N1 pandemic.

  6. Measurement of charm and beauty dijet cross sections in photoproduction at HERA using the H1 vertex detector

    International Nuclear Information System (INIS)

    Finke, L.

    2007-01-01

    A measurement of charm and beauty dijet photoproduction cross sections at the ep collider HERA is presented. The lifetime signature of c- and b-flavoured hadrons is exploited to determine the fractions of events in the sample containing charm or beauty. Differential dijet cross sections for charm and beauty, and their relative contributions to the flavour inclusive dijet photoproduction cross section, are measured. Taking into account the theoretical uncertainties, the charm cross sections are consistent with a QCD calculation in next-to-leading order, the predicted cross sections for beauty production being somewhat lower than the measurement. (author)

  7. Measurement of charm and beauty dijet cross sections in photoproduction at HERA using the H1 vertex detector

    International Nuclear Information System (INIS)

    Aktas, A.; Andreev, V.; Anthonis, T.

    2006-04-01

    A measurement of charm and beauty dijet photoproduction cross sections at the ep collider HERA is presented. Events are selected with two or more jets of transverse momentum p jet 1(2)t >11(8) GeV in the central range of pseudo-rapidity -0.9 jet 1(2) obs γ . Taking into account the theoretical uncertainties, the charm cross sections are consistent with a QCD calculation in next-to-leading order, while the predicted cross sections for beauty production are somewhat lower than the measurement. (Orig.)

  8. BES detector

    International Nuclear Information System (INIS)

    Bai, J.Z.; Bian, Q.; Chen, G.M.; Chen, L.J.; Chen, S.N.; Chen, Y.Q.; Chen, Z.Q.; Chi, Y.K.; Cui, H.C.; Cui, X.Z.; Deng, S.S.; Deng, Y.W.; Ding, H.L.; Dong, B.Z.; Dong, X.S.; Du, X.; Du, Z.Z.; Feng, C.; Feng, Z.; Fu, Z.S.; Gao, C.S.; Gao, M.L.; Gao, S.Q.; Gao, W.X.; Gao, Y.N.; Gu, S.D.; Gu, W.X.; Guan, Y.Z.; Guo, H.F.; Guo, Y.N.; Guo, Y.Y.; Han, S.W.; Han, Y.; Hao, W.; He, J.; He, K.R.; He, M.J.; Hou, X.J.; Hu, G.Y.; Hu, J.S.; Hu, J.W.; Huang, D.Q.; Huang, Y.Z.; Jia, Q.P.; Jiang, C.H.; Ju, Q.; Lai, Y.F.; Lang, P.F.; Li, D.S.; Li, F.; Li, H.; Li Jia; Li, J.T.; Li Jin; Li, L.L.; Li, P.Q.; Li, Q.M.; Li, R.B.; Li, S.Q.; Li, W.; Li, W.G.; Li, Z.X.; Liang, G.N.; Lin, F.C.; Lin, S.Z.; Lin, W.; Liu, Q.; Liu, R.G.; Liu, W.; Liu, X.; Liu, Z.A.; Liu, Z.Y.; Lu, C.G.; Lu, W.D.; Lu, Z.Y.; Lu, J.G.; Ma, D.H.; Ma, E.C.; Ma, J.M.; Mao, H.S.; Mao, Z.P.; Meng, X.C.; Ni, H.L.; Nie, J.; Nie, Z.D.; Niu, W.P.; Pan, L.J.; Qi, N.D.; Qian, J.J.; Qu, Y.H.; Que, Y.K.; Rong, G.; Ruan, T.Z.; Shao, Y.Y.; Shen, B.W.; Shen, D.L.; Shen, J.; Sheng, H.Y.; Sheng, J.P.; Shi, H.Z.; Song, X.F.; Sun, H.S.; Tang, F.K.; Tang, S.Q.; Tian, W.H.; Wang, F.; Wang, G.Y.; Wang, J.G.; Wang, J.Y.; Wang, L.S.; Wang, L.Z.; Wang, M.; Wang, P.; Wang, P.L.; Wang, S.M.; Wang, S.Q.; Wang, T.J.; Wang, X.W.; Wang, Y.Y.; Wang, Z.H.; Wang, Z.J.; Wei, C.L.; Wei, Z.Z.; Wu, J.W.; Wu, S.H.; Wu, S.Q.; Wu, W.M.; Wu, X.D.; Wu, Z.D.; Xi, D.M.; Xia, X.M.; Xiao, J.; Xie, P.P.; Xie, X.X.; Xu, J.G.; Xu, R.S.; Xu, Z.Q.; Xuan, B.C.; Xue, S.T.; Yan, J.; Yan, S.P.; Yan, W.G.; Yang, C.Z.; Yang, C.M.; Yang, C.Y.; Yang, X.F.; Yang, X.R.; Ye, M.H.; Yu, C.H.; Yu, C.S.; Yu, Z.Q.; Zhang, B.Y.; Zhang, C.D.; Zhang, C.C.; Zhang, C.Y.; Zhang, D.H.; Zhang, G.; Zhang, H.Y.; Zhang, H.L.; Zhang, J.W.; Zhang, L.S.; Zhang, S.Q.; Zhang, Y.P.; Zhang, Y.; Zhang, Y.M.; Zhao, D.X.; Zhao, J.W.; Zhao, M.; Zhao, P.D.; Zhao, P.P.; Zhao, W.R.; Zhao, Z.G.; Zhao, Z.Q.; Zheng, J.P.; Zheng, L.S.; Zheng, M.; Zheng, W.S.; Zheng, Z.P.; Zhong, G.P.; Zhou, G.P.; Zhou, H.S.; Zhou, J.; Zhou Li; Zhou Lin; Zhou, M.; Zhou, Y.S.; Zhou, Y.H.; Zhu, G.S.; Zhu, Q.M.; Zhu, S.G.; Zhu, Y.C.; Zhu, Y.S.; Zhuang, B.A.

    1994-01-01

    The Beijing Spectrometer (BES) is a general purpose solenoidal detector at the Beijing Electron Positron Collider (BEPC). It is designed to study exclusive final states in e + e - annihilations at the center of mass energy from 3.0 to 5.6 GeV. This requires large solid angle coverage combined with good charged particle momentum resolution, good particle identification and high photon detection efficiency at low energies. In this paper we describe the construction and the performance of BES detector. (orig.)

  9. Differential affinity of mammalian histone H1 somatic subtypes for DNA and chromatin

    Directory of Open Access Journals (Sweden)

    Mora Xavier

    2007-05-01

    Full Text Available Abstract Background Histone H1 is involved in the formation and maintenance of chromatin higher order structure. H1 has multiple isoforms; the subtypes differ in timing of expression, extent of phosphorylation and turnover rate. In vertebrates, the amino acid substitution rates differ among subtypes by almost one order of magnitude, suggesting that each subtype might have acquired a unique function. We have devised a competitive assay to estimate the relative binding affinities of histone H1 mammalian somatic subtypes H1a-e and H1° for long chromatin fragments (30–35 nucleosomes in physiological salt (0.14 M NaCl at constant stoichiometry. Results The H1 complement of native chromatin was perturbed by adding an additional amount of one of the subtypes. A certain amount of SAR (scaffold-associated region DNA was present in the mixture to avoid precipitation of chromatin by excess H1. SAR DNA also provided a set of reference relative affinities, which were needed to estimate the relative affinities of the subtypes for chromatin from the distribution of the subtypes between the SAR and the chromatin. The amounts of chromatin, SAR and additional H1 were adjusted so as to keep the stoichiometry of perturbed chromatin similar to that of native chromatin. H1 molecules freely exchanged between the chromatin and SAR binding sites. In conditions of free exchange, H1a was the subtype of lowest affinity, H1b and H1c had intermediate affinities and H1d, H1e and H1° the highest affinities. Subtype affinities for chromatin differed by up to 19-fold. The relative affinities of the subtypes for chromatin were equivalent to those estimated for a SAR DNA fragment and a pUC19 fragment of similar length. Avian H5 had an affinity ~12-fold higher than H1e for both DNA and chromatin. Conclusion H1 subtypes freely exchange in vitro between chromatin binding sites in physiological salt (0.14 M NaCl. The large differences in relative affinity of the H1 subtypes for

  10. Predicting H1N1 vaccine uptake and H1N1-related health beliefs: the role of individual difference in consideration of future consequences.

    Science.gov (United States)

    Nan, Xiaoli; Kim, Jarim

    2014-01-01

    This research examines the influence of individual difference in consideration of future consequences on H1N1 vaccine uptake and H1N1-related health beliefs (i.e., perceived susceptibility to and severity of the H1N1 flu, perceived efficacy and safety of the H1N1 vaccine, and perceived self-efficacy in obtaining the H1N1 vaccine). A survey of 411 college students showed that consideration of future consequences had no direct effect on vaccine uptake, but higher consideration of future consequences was associated with greater perceived severity of the flu, higher perceived effectiveness of the vaccine, and greater perceived self-efficacy. Additional analysis suggested that consideration of future consequences had a significant indirect effect on vaccine uptake through perceived vaccine efficacy. Results of the study also revealed gender and racial differences in some of the H1N1-related health beliefs. Implications of the findings for vaccine risk communication are discussed.

  11. Mitochondrial haplogroup H1 in north Africa: an early holocene arrival from Iberia.

    Directory of Open Access Journals (Sweden)

    Claudio Ottoni

    Full Text Available The Tuareg of the Fezzan region (Libya are characterized by an extremely high frequency (61% of haplogroup H1, a mitochondrial DNA (mtDNA haplogroup that is common in all Western European populations. To define how and when H1 spread from Europe to North Africa up to the Central Sahara, in Fezzan, we investigated the complete mitochondrial genomes of eleven Libyan Tuareg belonging to H1. Coalescence time estimates suggest an arrival of the European H1 mtDNAs at about 8,000-9,000 years ago, while phylogenetic analyses reveal three novel H1 branches, termed H1v, H1w and H1x, which appear to be specific for North African populations, but whose frequencies can be extremely different even in relatively close Tuareg villages. Overall, these findings support the scenario of an arrival of haplogroup H1 in North Africa from Iberia at the beginning of the Holocene, as a consequence of the improvement in climate conditions after the Younger Dryas cold snap, followed by in situ formation of local H1 sub-haplogroups. This process of autochthonous differentiation continues in the Libyan Tuareg who, probably due to isolation and recent founder events, are characterized by village-specific maternal mtDNA lineages.

  12. Finding the Higgs boson of the standard model in the channel ZH → e+e-b$\\bar{b}$ with the D0 detector at the Tevatron; Recherche du boson de Higgs du nideke standard dans le canal ZH → e+e-b$\\bar{b}$ avec le detecteur DØ aupres du Tevatron

    Energy Technology Data Exchange (ETDEWEB)

    Calpas, Betty Constante [Univ. of the Mediterranean, Marseille (France)

    2010-06-11

    The organization of this thesis consists of three main ideas: the first presents the theoretical framework and experimental, as well as objects used in the analysis and the second relates to the various work tasks of service that I performed on the calorimeter, and the third is the search for the Higgs boson in the channel ZH → e+e-b$\\bar{b}$. Thus, this thesis has the following structure: Chapter 1 is an introduction to the standard model of particle physics and the Higgs mechanism; Chapter 2 is an overview of the complex and the acceleration of the Tevatron at Fermilab DØ detector; Chapter 3 is an introduction to physical objects used in this thesis; Chapter 4 presents the study made on correcting the energy measured in the calorimeter; Chapter 5 describes the study of certification of electrons in the calorimeter; Chapter 6 describes the study of certification of electrons in the intercryostat region of calorimeter; Chapter 7 Detailed analysis on the search for Higgs production in the channel ZH → e+e-b$\\bar{b}$; and Chapter 8 presents the final results of the calculations of upper limits to the production cross section of the Higgs boson on a range of low masses.

  13. Search for new physics in the jets and missing transverse energy topology with the D0 detector at the Tevatron; Recherche de nouvelle physique dans la topologie a jets et energie transverse manquante avec le detecteur D0 au TeVatron

    Energy Technology Data Exchange (ETDEWEB)

    Makovec, N

    2006-05-15

    Although the standard model of particle physics agrees perfectly with experimental data, it is unlikely the final theory describing particles and their interactions. New phenomena has been searched in the jets and missing transverse energy topology. Such phenomena may be due to the pair production of leptoquarks decaying into a quark and a neutrino or the pair production of stops decaying into a charm and a neutralino which is assumed to be the lightest supersymmetric particle. These searches have been performed with the Ddiamter detector at hadronic collider TeVatron with a center of mass energy of 1.96 TeV. This kind of searches needs a good understanding of the jet energy calibration. The determination of the relative jet energy scale has allowed us to reduce the systematic uncertainties on the jet energy measurement when comparing the data and the simulation. Moreover a new method has been developed in order to correct simulated jets for the differences observed in the jet energy scale, the jet energy resolution and the jet reconstruction efficiency between the data and the simulation. The data analysis, performed with an integrated luminosity of 310 pb{sup -1}, has not observed any excess. This result are interpreted in terms of limit on the mass of the particles: leptoquarks with a mass smaller than 136 GeV and stops with a mass smaller than 131 GeV, for a neutralino mass equal to 46 GeV, are excluded with 95% confidence level. (author)

  14. Histone H1 heterogeneity in the midge, Chironomus thummi. Structural comparison of the H1 variants in an organism where their intrachromosomal localization is possible.

    Science.gov (United States)

    Hoyer-Fender, S; Grossbach, U

    1988-09-01

    1. Seven subfractions of histone H1 have been isolated and purified from larvae of Chironomus thummi (Diptera). They have been denominated I-1, II-1, II-2, II-3, III-1, III-2, and III-3, according to the order of migration in two steps of preparative electrophoresis. 2. The amino acid compositions are similar to those of other H1 histones. Subfractions I-1 and II-1 were found to contain one methionine and two tyrosine residues, II-2 contained two methionine and three tyrosine residues, and III-1 one methionine and three tyrosine residues. The other subfractions contained one or two methionine and two or three tyrosine residues. For subfractions I-1 and II-1 a chain length of about 252 amino acids was estimated. 3. Peptide pattern analyses after chemical cleavage at the methionine and tyrosine residues, and enzymatic cleavage with thrombin and chymotrypsin, respectively, showed that all subfractions have different individual primary structures. A comparison of peptide sizes and of the positions in the peptide patterns of epitopes recognized by monoclonal antibodies was made to check whether some of the subfractions could arise by proteolytic degradation of others. This possibility can be excluded for five of the subfractions and is very improbable for the two others. Treatment of C. thummi H1 with alkaline phosphatase did not change the pattern of subfractions, while the phosphorylated subfraction of histone H2A disappeared after this treatment. Most and very probably all subfractions are thus H1 sequence variants. 4. Inbred strains and individual larvae of C. thummi were found to comprise all seven variants. The H1 heterogeneity can therefore not be due to allelic polymorphism. Salivary gland nuclei were found to contain variant I-1 and at least some of the other variants. 5. H1 from Drosophila melanogaster and from calf thymus were used as reference molecules in all cleavage experiments and yielded the peptide patterns expected from the sequence. The comparison

  15. Vertex detectors

    International Nuclear Information System (INIS)

    Lueth, V.

    1992-07-01

    The purpose of a vertex detector is to measure position and angles of charged particle tracks to sufficient precision so as to be able to separate tracks originating from decay vertices from those produced at the interaction vertex. Such measurements are interesting because they permit the detection of weakly decaying particles with lifetimes down to 10 -13 s, among them the τ lepton and charm and beauty hadrons. These two lectures are intended to introduce the reader to the different techniques for the detection of secondary vertices that have been developed over the past decades. The first lecture includes a brief introduction to the methods used to detect secondary vertices and to estimate particle lifetimes. It describes the traditional technologies, based on photographic recording in emulsions and on film of bubble chambers, and introduces fast electronic registration of signals derived from scintillating fibers, drift chambers and gaseous micro-strip chambers. The second lecture is devoted to solid state detectors. It begins with a brief introduction into semiconductor devices, and then describes the application of large arrays of strip and pixel diodes for charged particle tracking. These lectures can only serve as an introduction the topic of vertex detectors. Time and space do not allow for an in-depth coverage of many of the interesting aspects of vertex detector design and operation

  16. Smoke detectors

    International Nuclear Information System (INIS)

    Macdonald, E.

    1976-01-01

    A smoke detector is described consisting of a ventilated ionisation chamber having a number of electrodes and containing a radioactive source in the form of a foil supported on the surface of the electrodes. This electrode consists of a plastic material treated with graphite to render it electrically conductive. (U.K.)

  17. Semiconductor Detectors

    International Nuclear Information System (INIS)

    Cortina, E.

    2007-01-01

    Particle detectors based on semiconductor materials are among the few devices used for particle detection that are available to the public at large. In fact we are surrounded by them in our daily lives: they are used in photoelectric cells for opening doors, in digital photographic and video camera, and in bar code readers at supermarket cash registers. (Author)

  18. Capillary detectors

    International Nuclear Information System (INIS)

    Konijn, J.; Winter, K.; Vilain, P.; Wilquet, G.; Fabre, J.P.; Kozarenko, E.; Kreslo, I.; Goldberg, J.; Hoepfner, K.; Bay, A.; Currat, C.; Koppenburg, P.; Frekers, D.; Wolff, T.; Buontempo, S.; Ereditato, A.; Frenkel, A.; Liberti, B.; Martellotti, G.; Penso, G.; Ekimov, A.; Golovkin, S.; Govorun, V.; Medvedkov, A.; Vasil'chenko, V.

    1998-01-01

    The option for a microvertex detector using glass capillary arrays filled with liquid scintillator is presented. The status of capillary layers development and possible read-out techniques for high rate environment are reported. (Copyright (c) 1998 Elsevier Science B.V., Amsterdam. All rights reserved.)

  19. Publications | Page 221 | CRDI - Centre de recherches pour le ...

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    Mariage et divorce à Dakar : itinéraires féminins (restricted access) · Trois exemples de recherche-action dans le secteur public québécois (open access) · Exercice Outcome Mapping : TIC et Gouvernance Locale (restricted access) · Atelier de formation des membres de la COPES-AOC en mobilisation des ressources, ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    Amérique du Nord et de l'Europe pour inclure maintenant un plus grand nombre d'établissements de recherche africains. Activité antérieure : Le CRDI au Congrès mondial sur la santé publique 2015. Le 14e Congrès mondial sur la santé publique ...

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    ... charge de morbidité croissante liée aux maladies non transmissibles (MNT) dans les ... les compétences en recherche et les connaissances en Afrique pour garantir la ... Prevalence and predictors of cigarette smoking among adolescents of ...

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    ), organisation non gouvernementale indépendante, participe aux recherches et aux activités de promotion en matière de législation agraire depuis l'adoption des accords de paix il y a dix ans. Date de début : 30 juin 2007. End Date: 1 ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

  5. Financing Innovation | CRDI - Centre de recherches pour le ...

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    Universidade Federal do Rio de Janeiro (UFRJ), au Brésil. Marcelo G. Pessoa de Matos est professeur adjoint et chercheur principal au RedeSist, un réseau de recherche sur les systèmes de production et d'innovation locaux établi ...

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    Inde. S'il se peut bien que les changements climatiques viennent aggraver le problème, il ressort de recherches menées dans deux bassins versants du sud du pays que la pollution industrielle, l'exploitation non réglementée des ressources et ...

  7. Initiative Think tank | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    L'ITT est le fruit d'un partenariat regroupant cinq bailleurs de fonds. Lancée en 2008, l'ITT est administrée par le Centre de Recherches pour le Développement International (CRDI), un organisme canadien.

  8. Ce que nous faisons | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le CRDI appuie des travaux de recherche dans les pays en voie de développement en vue de produire un changement réel et durable. Ce savoir peut servir d'outil pour résoudre des problèmes mondiaux urgents. Nous partageons ce savoir avec les autres en :

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    africain. Il y a deux ans, le Centre de recherches pour le développement ... African Youth on the Information Highway : Participation and Leadership in Community Development. Tout comme elle l'a fait dans le Nord industrialisé, la révolution de ...

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    africain. Il y a deux ans, le Centre de recherches pour le développement ... African Youth on the Information Highway : Participation and Leadership in Community Development. Tout comme elle l'a fait dans le Nord industrialisé, la révolution de ...

  11. La recherche en action : des solutions locales, des effets durables ...

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    15 déc. 2010 ... Le Centre de recherches pour le développement international (CRDI) appuie la production et l'application de connaissances qui améliorent de façon notable la situation des habitants des pays en développement.

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    Avec nos livres, nos articles, nos publications de recherche et nos études, ... Téléphones mobiles, Internet et sexospécificité au Myanmar ... Les formateurs ont immédiatement eu la chance de mettre en pratique leurs nouvelles compétences.

  13. David M. Malone | CRDI - Centre de recherches pour le ...

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    Cette exposition précoce à un mode de vie cosmopolite a eu l'heur de plaire au ... Une bonne partie des travaux de recherche de l'institut portent sur l'ONU et les .... INTERNET5 : Favoriser l'autonomisation des femmes au moyen d'Internet.

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    ... la recherche sur des questions essentielles de développement international. ... le courrier électronique, Internet; la télémédecine, l'enseignement à distance, ... agriculteurs des régions où il y a eu domestication et évolution des cultur.

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    Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ... de développement (BAD) a eu lieu du 2 au 5 décembre 2015 en Azerbaïdjan. ... Les lieux d'accès public, notamment les cafés Internet urbains et les ...

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    ... des gouvernements étrangers ont eu des effets économiques positifs tout comme ... L'accès à Internet est devenu une priorité pour les pays en développement. ... les régions rurales mal desservies du Nigeria grâce à la recherche visant la ...

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    Ce projet de recherche permettra à des femmes, des hommes et des enfants pauvres et vulnérables de faire face et de s'adapter aux changements climatiques dans la région asiatique de l'Hindu Kush-Himalaya. Sujet(s): ADAPTATION. Région(s): Bangladesh, India, Nepal, Pakistan. Financement total : CA$ 13,500,000.00.

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    Asie centrale. Asie centrale. Read more about Renforcement de la recherche en sciences sociales en Iraq. Langue French. Read more about Strengthening Social Science Research in Iraq. Langue English. Read more about Genetically Modified Organisms : Public Knowledge, Attitudes and Perceptions (India). Langue ...

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    Avec nos livres, nos articles, nos publications de recherche et nos études, nous ... les régions périurbaines ont des caractéristiques sociales, économiques et ... de Tecnologías y Ciencias Aplicadas ont constaté que les poissons contaminés ...

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    Avec nos livres, nos articles, nos publications de recherche et nos études, nous ... les régions périurbaines ont des caractéristiques sociales, économiques et ... de Tecnologías y Ciencias Aplicadas ont constaté que les poissons contaminés ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    Publication du rapport de BSR sur le travail des enfants en Birmanie. Le CRDI finance plusieurs projets de recherche sur les facteurs expliquant le travail des enfants, incluant le rapport intitulé 'Child labor in Myanmar's Garment Sector' écrit récemment par l'organisme Business for Social Responsibility (BSR).

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    ... en appuyant la recherche sur des questions essentielles de développement international. ... Dix ans de réforme : Politique scientifique et technologique en Chine ... Knowledge Shared : Participatory Evaluation in Development Cooperation ... Le droit au logement est un droit fondamental de la personne réaffirmé en juin ...

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    Asie du Sud (le Bangladesh, l'Inde, le Népal, le Pakistan et le Sri Lanka). Parmi les 16 demandeurs d'Asie du Sud retenus, neuf viennent de l'Inde. La recherche sur les politiques en Asie du Sud s'effectue principalement en Inde, forte d'une ...

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    Qualitative Research for Tobacco Control : A How-to Introductory Manual for Researchers and Development Practitioners. Ce guide pratique est destiné à encourager les intervenants, où qu'ils se trouvent dans le monde, à s'engager dans la recherche contre le tabac en faisant appel à des méthodes et des outils qualita.

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  12. Recherche sur l'adaptation aux changements climatiques

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    Corey Piccioni

    consortiums travaillent dans des zones vulnérables aux changements climatiques en Afrique et en Asie, notamment dans les bassins hydrographiques alimentés .... Le projet de recherche Pathways to Resilience in Semi-Arid Economies (PRISE) vise à réduire les risques et à opti- miser les possibilités de développement ...

  13. African Climate Change Fellowship | CRDI - Centre de recherches ...

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    Extrants. Articles de revue. Spatial fields' dispersion as a farmer strategy to reduce agro-climatic risk at the household level in pearl millet-based systems in the Sahel : a modeling ... L'Initiative des conseils subventionnaires de la recherche scientifique en Afrique subsaharienne remporte le prix de la diplomatie scientifique.

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    Nous sommes déterminés à améliorer les conditions de vie et les moyens de subsistance en appuyant la recherche sur des questions essentielles de développement international. Les publications du CRDI et des chercheurs que nous subventionnons constituent un important moyen de susciter des changements positifs.

  17. Professorat de recherche sur les droits de la personne reconnus ...

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    Pour ce projet, le CRDI s'associe à la Norman Paterson School of International Affairs (NPSIA) pour réaliser un programme de recherche portant sur les droits de la personne reconnus internationalement. La subvention servira à payer pendant deux ans la moitié du salaire et des avantages sociaux du professeur agrégé ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    Nous sommes déterminés à améliorer les conditions de vie et les moyens de subsistance en appuyant la recherche sur des questions essentielles de développement international. Les publications du CRDI et des chercheurs que nous subventionnons constituent un important moyen de susciter des changements positifs.

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

  1. Entretien avec Susan Holtz | CRDI - Centre de recherches pour le ...

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    26 nov. 2010 ... ... Centre de recherches pour le développement international comme l'un des ... Toutefois, le discours public sur l'intégration d'objectifs environnementaux et .... très conservatrice des experts du droit commercial international, ...

  2. Mexico : tous les projets | Page 4 | CRDI - Centre de recherches ...

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    Le code barre ADN est un nouvel outil de recherche taxinomique. Date de début : 1 avril 2010. End Date: 1 octobre 2013. Sujet: BIOLOGY, BIODIVERSITY, ECOLOGY. Région: Argentina, South America, Costa Rica, North and Central America, Kenya, Peru, South Africa, North of Sahara, South of Sahara, Mexico, Canada.

  3. canada : tous les projets | Page 8 | CRDI - Centre de recherches ...

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    Région: Brazil, South America, Canada, North and Central America, India, Far East Asia, South Korea, Central Asia, South Asia. Programme: Économies en réseaux. Financement total : CA$ 203,800.00. Modalités institutionnelles pour faire des partenariats de recherche universités-communautés une pratique courante.

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

  13. Publications | Page 135 | CRDI - Centre de recherches pour le ...

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    Visitez la Bibliothèque numérique du CRDI maintenant. ... ÉTUDE DE CAS — mondiale : Repenser les stratégies de recherche agricole. Repenser ... La gestion de la demande en eau, un instrument de justice sociale – Les femmes, comme les hommes, ont beaucoup à offrir en matière de gestion des ressources hydriques.

  14. Publications | Page 84 | CRDI - Centre de recherches pour le ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement ... Utilisez cet outil de recherche pour trouver une publication précise liée à votre ... La gestion de la demande en eau, un instrument de justice sociale.

  15. TTI Phase 2 Institutional Support: Consortium pour la Recherche E ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Improved research, better performance ... et sociale (CRES) en tant qu'organisme crédible de recherche sur les politiques publiques au Sénégal,. ... Sexospécificités et développement de l'entreprise en Afrique - étude interpays comparative.

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

  18. Publications | Page 231 | CRDI - Centre de recherches pour le ...

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    Projet de recherche "intégration des technologies de l'information et de la communication dans les apprentissages de base à l'école élémentaire au Sénégal" : rapport technique final (restricted access) ...

  19. Publications | Page 225 | CRDI - Centre de recherches pour le ...

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    Projet de recherche "intégration des technologies de l'information et de la communication dans les apprentissages de base à l'école élémentaire au Sénégal" : rapport technique final (restricted access) ...

  20. cambodia : tous les projets | Page 4 | CRDI - Centre de recherches ...

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    Sujet: TRANSPORT INFRASTRUCTURE, INTERNATIONAL TRANSPORT, REGIONAL INTEGRATION, TRADE FACILITATION. Région: Central Asia, Far East Asia, South Asia, Cambodia, China, Laos, Viet Nam, Thailand. Programme: Emploi et croissance. Financement total : CA$ 300,000.00. Programme de recherche sur ...

  1. Droits d'auteur | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Droits d'auteur détenus par le CRDI Sauf indication contraire, les droits d'auteur relatifs aux documents mis en ligne sur le présent site Web sont détenus par le Centre de recherches pour le développement international (CRDI).

  2. Publications | Page 103 | CRDI - Centre de recherches pour le ...

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    Le FIE 2008 fait avancer le cadre écobiosocial de l'OMS. Le Programme spécial de recherche et de formation concernant les maladies tropicales (TDR) de l'OMS a élaboré le concept du champ « écobiosocial », qui combine les perspectives écologiques, biologiques et sociales « pour mieux.

  3. Publications | Page 208 | CRDI - Centre de recherches pour le ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

  4. Publications | Page 32 | CRDI - Centre de recherches pour le ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

  5. Publications | Page 173 | CRDI - Centre de recherches pour le ...

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    E-Commerce in the Asian Context : Selected Case Studies. Le commerce électronique en Asie retient beaucoup l'attention en raison de la prolifération des connexions Internet et des technologies connexes dans la région. Face à cette tendance, le Centre de recherches pour le développement international (.

  6. Publications | Page 165 | CRDI - Centre de recherches pour le ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en ... Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons ... La décentralisation de la gestion forestière met-elle les forêts en danger ou ...

  7. Publications | Page 163 | CRDI - Centre de recherches pour le ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en ... Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons ... La décentralisation de la gestion forestière met-elle les forêts en danger ou ...

  8. Publications | Page 175 | CRDI - Centre de recherches pour le ...

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    Qualitative Research for Tobacco Control : A How-to Introductory Manual for Researchers and Development Practitioners. Ce guide pratique est destiné à encourager les intervenants, où qu'ils se trouvent dans le monde, à s'engager dans la recherche contre le tabac en faisant appel à des méthodes et des outils qualitatifs.

  9. Publications | Page 73 | CRDI - Centre de recherches pour le ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

  10. Publications | Page 87 | CRDI - Centre de recherches pour le ...

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    Le CRDI collabore avec les chercheurs et les établissements des pays en développement au renforcement des capacités locales par le truchement du financement, de la mise en commun des connaissances et de la formation. Avec nos livres, nos articles, nos publications de recherche et nos études, nous visons à ...

  11. Publications | Page 133 | CRDI - Centre de recherches pour le ...

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    Le 28 juin 2006, le domaine de programme Innovation, politique et science (IPS) a présenté au Conseil des gouverneurs du CRDI un plan stratégique pour orienter la phase initiale (2006 2011) des recherches ... Simultanément, il explore certaines des options permettant d'envisager la revitalisation de ce processus.

  12. Histones H10a and H10b are the same as CHO histones H1(III) and H1(IV):new features of H10 phosphorylation during the cell cycle

    International Nuclear Information System (INIS)

    D'Anna, J.A.; Gurley, L.R.; Becker, R.R.

    1981-01-01

    Two histone H1 fractions [H1(I) and H1(II) and two histone H1 0 fractions (H1 0 a and H1 0 b) have been isolated from butyrate-treated Chinese hamster (line CHO) cells by guanidine hydrochloride gradient chromatography on Bio-Rex 70 ion-exchange resin. The fractions have been identified by electrophoresis and amino acid analyses. Electrophoretic analysis of cyanogen bromide treated H1 0 in long acid-urea-polyacrylamide gels suggests that H1 0 a and H1 0 b differ, at least, within the 20-30 residue fragment(s) removed by the cyanogen bromide clevage. Shallow-gradient Bio-Rex 70 chromatography indicates that histones H1 0 a and H1 0 b are the same as the respective CHO histones, H1(III) and H1(IV). This identification and the phosphate incorporation data of Gurley et al. (1975) reveal new features about H1 0 phosphorylation: (1) following release from G 1 arrest, H1 0 a and H1 0 b become phosphorylated in late G 1 prior to DNA synthesis; (2) H1 0 a and H1 0 b are phosphorylated at similar rates throughout the cell cycle. These and other data demonstrate that histone H1 0 is phosphorylated in a cell cycle dependent fashion which mimics that of histone H1

  13. The H1 linker histones: multifunctional proteins beyond the nucleosomal core particle.

    Science.gov (United States)

    Hergeth, Sonja P; Schneider, Robert

    2015-11-01

    The linker histone H1 family members are a key component of chromatin and bind to the nucleosomal core particle around the DNA entry and exit sites. H1 can stabilize both nucleosome structure and higher-order chromatin architecture. In general, H1 molecules consist of a central globular domain with more flexible tail regions at both their N- and C-terminal ends. The existence of multiple H1 subtypes and a large variety of posttranslational modifications brings about a considerable degree of complexity and makes studying this protein family challenging. Here, we review recent progress in understanding the function of linker histones and their subtypes beyond their role as merely structural chromatin components. We summarize current findings on the role of H1 in heterochromatin formation, transcriptional regulation and embryogenesis with a focus on H1 subtypes and their specific modifications. © 2015 The Authors.

  14. Thermodynamical study of interaction of histone H1 chromosomal protein and mitoxantrone anticancer drug

    International Nuclear Information System (INIS)

    Jafargholizadeh, Naser; Zargar, Seyed Jalal; Safarian, Shahrokh; Habibi-Rezaei, Mehran

    2012-01-01

    Highlights: ► For the first time, our results show mitoxantrone anticancer drug binds to histone H1, via hydrophobic, hydrogen, van der Waals and electrostatic interactions. ► Binding of mitoxantrone molecules to histone H1 is positive cooperative. ► Histone H1 may be considered as a new target for mitoxantrone at the chromatin level. - Using ultraviolet spectroscopy technique, we have investigated the interaction of anticancer drug, mitoxantrone with calf thymus histone H1 chromosomal protein in 100 mM phosphate buffer, pH 7.0, at temperatures 300 and 310 K. UV spectroscopy results show interactions between mitoxantrone and histone H1 with a positive cooperative binding process which was confirmed by Scatchard plot. According to the obtained results, it is concluded that histone H1 can be considered as a target for mitoxantrone binding at the chromatin level.

  15. Characteristics of atopic children with pandemic H1N1 influenza viral infection: pandemic H1N1 influenza reveals 'occult' asthma of childhood.

    Science.gov (United States)

    Hasegawa, Shunji; Hirano, Reiji; Hashimoto, Kunio; Haneda, Yasuhiro; Shirabe, Komei; Ichiyama, Takashi

    2011-02-01

    The number of human cases of pandemic H1N1 influenza viral infection has increased in Japan since April 2009, as it has worldwide. This virus is widespread in the Yamaguchi prefecture in western Japan, where most infected children exhibited respiratory symptoms. Bronchial asthma is thought to be one of the risk factors that exacerbate respiratory symptoms of pandemic H1N1-infected patients, but the pathogenesis remains unclear. We retrospectively investigated the records of 33 children with pandemic H1N1 influenza viral infection who were admitted to our hospital between October and December 2009 and analyzed their clinical features. The percentage of children with asthma attack, with or without abnormal findings on chest radiographs (pneumonia, atelectasis, etc.), caused by pandemic H1N1 influenza infection was significantly higher than that of children with asthma attack and 2008-2009 seasonal influenza infection. Of the 33 children in our study, 22 (66.7%) experienced an asthma attack. Among these children, 20 (90.9%) did not receive long-term management for bronchial asthma, whereas 7 (31.8%) were not diagnosed with bronchial asthma and had experienced their first asthma attack. However, the severity of the attack did not correlate with the severity of the pulmonary complications of pandemic H1N1 influenza viral infection. The pandemic H1N1 influenza virus greatly increases the risk of lower respiratory tract complications such as asthma attack, pneumonia, and atelectasis, when compared to the seasonal influenza virus. Furthermore, our results suggest that pandemic H1N1 influenza viral infection can easily induce a severe asthma attack, pneumonia, and atelectasis in atopic children without any history of either an asthma attack or asthma treatment. © 2011 John Wiley & Sons A/S.

  16. Comparative analyses of pandemic H1N1 and seasonal H1N1, H3N2, and influenza B infections depict distinct clinical pictures in ferrets.

    Directory of Open Access Journals (Sweden)

    Stephen S H Huang

    Full Text Available Influenza A and B infections are a worldwide health concern to both humans and animals. High genetic evolution rates of the influenza virus allow the constant emergence of new strains and cause illness variation. Since human influenza infections are often complicated by secondary factors such as age and underlying medical conditions, strain or subtype specific clinical features are difficult to assess. Here we infected ferrets with 13 currently circulating influenza strains (including strains of pandemic 2009 H1N1 [H1N1pdm] and seasonal A/H1N1, A/H3N2, and B viruses. The clinical parameters were measured daily for 14 days in stable environmental conditions to compare clinical characteristics. We found that H1N1pdm strains had a more severe physiological impact than all season strains where pandemic A/California/07/2009 was the most clinically pathogenic pandemic strain. The most serious illness among seasonal A/H1N1 and A/H3N2 groups was caused by A/Solomon Islands/03/2006 and A/Perth/16/2009, respectively. Among the 13 studied strains, B/Hubei-Wujiagang/158/2009 presented the mildest clinical symptoms. We have also discovered that disease severity (by clinical illness and histopathology correlated with influenza specific antibody response but not viral replication in the upper respiratory tract. H1N1pdm induced the highest and most rapid antibody response followed by seasonal A/H3N2, seasonal A/H1N1 and seasonal influenza B (with B/Hubei-Wujiagang/158/2009 inducing the weakest response. Our study is the first to compare the clinical features of multiple circulating influenza strains in ferrets. These findings will help to characterize the clinical pictures of specific influenza strains as well as give insights into the development and administration of appropriate influenza therapeutics.

  17. Classical and semi-classical treatments of Li3+, Ne10++H(1s) collisions

    International Nuclear Information System (INIS)

    Errea, L F; Illescas, Clara; Mendez, L; Pons, B; Riera, A; Suarez, J

    2004-01-01

    We perform molecular close-coupling and impact-parameter classical trajectory Monte Carlo calculations of total and partial cross sections for capture and ionization in collisions of highly charged ions on H(1s). We first consider Li 3+ +H(1s) as a benchmark to ascertain the complementarity of the methods, and then Ne 10+ +H(1s), which has been scarcely studied up to now, and has recently become of interest for fusion plasma research

  18. Measurement of the longitudinal proton structure function in diffraction at the H1 experiment and prospects for diffraction at LHC

    International Nuclear Information System (INIS)

    Salek, David

    2011-05-01

    A measurement of the longitudinal diffractive structure function F L D using the H1 detector at HERA is presented. The structure function is extracted from first measurements of the diffractive cross section ep→eXY at centre of mass energies √(s) of 225 and 252 GeV at high values of inelasticity y, together with a new measurement at √(s) of 319 GeV, using data taken in 2006 and 2007. Previous H1 data at √(s) of 301 GeV complete the kinematic coverage needed to extract F L D in the range of photon virtualities 2.5 2 2 and fractional proton longitudinal momentum loss 10 -4 P -2 . The measured F L D is compared with leading twist predictions based on diffractive parton densities extracted in NLO QCD fits to previous diffractive DIS data and to a model which additionally includes a higher twist contribution derived from a colour dipole approach. The photoabsorption ratio for diffraction RD is extracted for Q 2 >7 GeV 2 and compared to the analogous quantity for inclusive DIS. (orig.)

  19. Measurement of the longitudinal proton structure function in diffraction at the H1 experiment and prospects for diffraction at LHC

    Energy Technology Data Exchange (ETDEWEB)

    Salek, David

    2011-05-15

    A measurement of the longitudinal diffractive structure function F{sub L}{sup D} using the H1 detector at HERA is presented. The structure function is extracted from first measurements of the diffractive cross section ep{yields}eXY at centre of mass energies {radical}(s) of 225 and 252 GeV at high values of inelasticity y, together with a new measurement at {radical}(s) of 319 GeV, using data taken in 2006 and 2007. Previous H1 data at {radical}(s) of 301 GeV complete the kinematic coverage needed to extract F{sub L}{sup D} in the range of photon virtualities 2.57 GeV{sup 2} and compared to the analogous quantity for inclusive DIS. (orig.)

  20. Search for Higgs Boson of Minimal Standard Model in the hadronic final states with the detector ALEPH at LEP 2; Recherche du boson de Higgs du Modele Standard Minimal dans les etats finals hadroniques avec le detecteur ALEPH a LEP 2

    Energy Technology Data Exchange (ETDEWEB)

    Deschamps, Olivier [Lab. de Physique Corpusculaire, Clermont-Ferrand-2 Univ., 63 - Aubiere (France)

    1999-04-16

    In the Standard Model framework of the particle physics the mass of fermions and electroweak gauge boson mass is related to a scalar sector. In the Minimal Version of the Standard Model, a neutral scalar particle is predicted: the Higgs boson. Its mass is a free parameter of the model. The search for this boson has been actively performed at the LEP collider and it has been extended by the recent increase of its energy (LEP 2). In addition, due to the increase of the signal to background ratio at LEP 2, the data analysis has been extended to new channels. This is particularly the case of the dominant, HZ {yields} hadrons, channel leading to 65% of the e{sup +}e{sup -} {yields} HZ production process final states at LEP. The aim of the work presented in this document, is the search of the Minimal Standard Model Higgs boson in the fully hadronic final state data recorded by the ALEPH detector at LEP 2 energies. A selection tool based on an artificial neural network multi-variate method, has been developed in order to separate the signal process from known Standard Model background processes. The neural network method allows to combine non-linearly the information describing the signal, and to reach performances better than those obtained by classical method based on cuts. No evidence of signal has been seen in the data collected by ALEPH up to {radical}s = 189 GeV. Thirty-two candidates has been selected in agreement with the 26.3 events expected for the background processes. Combining all channels from Higgs boson search, the limit m{sub H} > 90.2 GeV/c{sup 2} is obtained with a 95% confidence level. (author)

  1. The first Swedish H1N2 swine influenza virus isolate represents an uncommon reassortant

    OpenAIRE

    Renström Lena HM; Isaksson Mats; Berg Mikael; Zohari Siamak; Widén Frederik; Metreveli Giorgi; Bálint Ádám; Wallgren Per; Belák Sándor; Segall Thomas; Kiss István

    2009-01-01

    Abstract The European swine influenza viruses (SIVs) show considerable diversity comprising different types of H1N1, H3N2, and H1N2 strains. The intensifying full genome sequencing efforts reveal further reassortants within these subtypes. Here we report the identification of an uncommon reassortant variant of H1N2 subtype influenza virus isolated from a pig in a multisite herd where H1N2 swine influenza was diagnosed for the first time in Sweden during the winter of 2008-2009. The majority o...

  2. Two genotypes of H1N2 swine influenza viruses appeared among pigs in China.

    Science.gov (United States)

    Xu, Chuantian; Zhu, Qiyun; Yang, Huanliang; Zhang, Xiumei; Qiao, Chuanling; Chen, Yan; Xin, Xiaoguang; Chen, Hualan

    2009-10-01

    H1N2 is one of the main subtypes of influenza, which circulates in swine all over the world. To investigate the prevalence and genetic of H1N2 in swine of China. Two H1N2 swine influenza viruses were isolated from Tianjin and Guangdong province of China in 2004 and 2006, respectively. The molecular evolution of eight gene segments was analyzed. A/Swine/Tianjin/1/2004 has low identity with A/Swine/Guangdong/2006; in the phylogenetic tree of PA gene, A/Swine/Guangdong/1/2006 and A/Swine/Guangxi/1/2006 along with the H1N2 swine isolates of North America formed a cluster; and A/Swine/Tianjin/2004 and A/Swine/Zhejiang/2004, along with the classical H1N1 swine isolates formed another cluster; except that NA gene of A/Swine/Tianjin/1/2004 fell into the cluster of the H3N2 human influenza virus, indicating the reassortment between H3N2 human and H1N1 swine influenza viruses. Two different genotypes of H1N2 appeared among pigs in China. A/swine/Guangdong/1/06 was probably from H1N2 swine influenza viruses of North America; while A/swine/Tianjin/1/04 maybe come from reassortments of classical H1N1 swine and H3N2 human viruses prevalent in North America.

  3. A reverse genetic analysis of human Influenza A virus H1N2

    OpenAIRE

    Anton, Aline

    2010-01-01

    Reassortment between influenza A viruses of different subtypes rarely appears. Even in a community where H1N1 and H3N2 viruses co-circulate, reassortment to produce persistent viruses of mixed gene segments does not readily occur. H1N2 viruses, that circulated between 2001-2003 were considered to have arisen through the reassortment of the two human influenza subtypes H1N1 and H3N2. Due to the fact they make such a rare appearance, H1N2 viruses used to have new characteristics compared to the...

  4. Reasons for Low Pandemic H1N1 2009 Vaccine Acceptance within a College Sample

    Directory of Open Access Journals (Sweden)

    Russell D. Ravert

    2012-01-01

    Full Text Available This study examined health beliefs associated with novel influenza A (H1N1 immunization among US college undergraduates during the 2009-2010 pandemic. Undergraduates (ages 18–24 years from a large Midwestern University were invited to complete an online survey during March, 2010, five months after H1N1 vaccines became available. Survey items measured H1N1 vaccine history and H1N1-related attitudes based on the health belief literature. Logistic regression was used to identify attitudes associated with having received an H1N1 vaccine, and thematic analysis of student comments was conducted to further understand influences on vaccine decisions. Among the 296 students who participated in the survey, 15.2% reported having received an H1N1 vaccine. In regression analysis, H1N1 immunization was associated with seasonal flu vaccine history, perceived vaccine effectiveness, perceived obstacles to vaccination, and vaccine safety concerns. Qualitative results illustrate the relationship of beliefs to vaccine decisions, particularly in demonstrating that students often held concerns that vaccine could cause H1N1 or side effects. Vaccine safety, efficacy, and obstacles to immunization were major considerations in deciding whether to accept the H1N1 pandemic vaccine. Therefore, focusing on those aspects might be especially useful in future vaccine efforts within the college population.

  5. Histone H1 phosphorylation is associated with transcription by RNA polymerases I and II

    Science.gov (United States)

    Zheng, Yupeng; John, Sam; Pesavento, James J.; Schultz-Norton, Jennifer R.; Schiltz, R. Louis; Baek, Sonjoon; Nardulli, Ann M.; Hager, Gordon L.; Kelleher, Neil L.

    2010-01-01

    Histone H1 phosphorylation affects chromatin condensation and function, but little is known about how specific phosphorylations impact the function of H1 variants in higher eukaryotes. In this study, we show that specific sites in H1.2 and H1.4 of human cells are phosphorylated only during mitosis or during both mitosis and interphase. Antisera generated to individual H1.2/H1.4 interphase phosphorylations reveal that they are distributed throughout nuclei and enriched in nucleoli. Moreover, interphase phosphorylated H1.4 is enriched at active 45S preribosomal RNA gene promoters and is rapidly induced at steroid hormone response elements by hormone treatment. Our results imply that site-specific interphase H1 phosphorylation facilitates transcription by RNA polymerases I and II and has an unanticipated function in ribosome biogenesis and control of cell growth. Differences in the numbers, structure, and locations of interphase phosphorylation sites may contribute to the functional diversity of H1 variants. PMID:20439994

  6. Bilan du programme autrichien de recherche sur les paysages

    Directory of Open Access Journals (Sweden)

    Karolina Begusch-Pfefferkorn

    2009-03-01

    Full Text Available Austrian Landscape Research, a programme of the Austrian Ministry of Science, has created scientific foundations for the sustainable development of Austrian landscapes and regions (plus bordering regions. Landscapes and regions were to be explored from different angles; implementing the research findings was to be part of the research work. The programme was designed to make room for science open to society, for unconventional ideas, methods, and courses of action. Programmatic targets and research principles supported this intent. The results of the programme met with national and international approval. The ALR knowledge balance is an attempt at presenting and assessing the achievements of this comprehensive contract research programme.Le programme du Ministère autrichien des Sciences, intitulé « Recherche sur le paysage autrichien », visait à construire les fondements scientifiques d’un développement durable des paysages et des régions de l’Autriche et des territoires limitrophes. Les paysages et les régions ont été étudiés selon différentes approches disciplinaires et la mise en pratique des résultats de cette étude était partie prenante du programme de recherche. La vocation de ce programme était de faire la place à une science ouverte sur la société, à des idées, méthodes et pratiques non conventionnelles. Les objectifs du programme et les principes de recherche vont dans le sens de ces exigences. Les résultats du programme ont été reconnus sur le plan national et international. Le bilan des connaissances du programme de recherche sur le paysage autrichien (KLF a pour but de présenter et d’évaluer les performances de ce vaste programme de recherche.

  7. Prior infection of chickens with H1N1 or H1N2 avian influenza elicits partial heterologous protection against highly pathogenic H5N1.

    Science.gov (United States)

    Nfon, Charles; Berhane, Yohannes; Pasick, John; Embury-Hyatt, Carissa; Kobinger, Gary; Kobasa, Darwyn; Babiuk, Shawn

    2012-01-01

    There is a critical need to have vaccines that can protect against emerging pandemic influenza viruses. Commonly used influenza vaccines are killed whole virus that protect against homologous and not heterologous virus. Using chickens we have explored the possibility of using live low pathogenic avian influenza (LPAI) A/goose/AB/223/2005 H1N1 or A/WBS/MB/325/2006 H1N2 to induce immunity against heterologous highly pathogenic avian influenza (HPAI) A/chicken/Vietnam/14/2005 H5N1. H1N1 and H1N2 replicated in chickens but did not cause clinical disease. Following infection, chickens developed nucleoprotein and H1 specific antibodies, and reduced H5N1 plaque size in vitro in the absence of H5 neutralizing antibodies at 21 days post infection (DPI). In addition, heterologous cell mediated immunity (CMI) was demonstrated by antigen-specific proliferation and IFN-γ secretion in PBMCs re-stimulated with H5N1 antigen. Following H5N1 challenge of both pre-infected and naïve controls chickens housed together, all naïve chickens developed acute disease and died while H1N1 or H1N2 pre-infected chickens had reduced clinical disease and 70-80% survived. H1N1 or H1N2 pre-infected chickens were also challenged with H5N1 and naïve chickens placed in the same room one day later. All pre-infected birds were protected from H5N1 challenge but shed infectious virus to naïve contact chickens. However, disease onset, severity and mortality was reduced and delayed in the naïve contacts compared to directly inoculated naïve controls. These results indicate that prior infection with LPAI virus can generate heterologous protection against HPAI H5N1 in the absence of specific H5 antibody.

  8. Prior infection of chickens with H1N1 or H1N2 avian influenza elicits partial heterologous protection against highly pathogenic H5N1.

    Directory of Open Access Journals (Sweden)

    Charles Nfon

    Full Text Available There is a critical need to have vaccines that can protect against emerging pandemic influenza viruses. Commonly used influenza vaccines are killed whole virus that protect against homologous and not heterologous virus. Using chickens we have explored the possibility of using live low pathogenic avian influenza (LPAI A/goose/AB/223/2005 H1N1 or A/WBS/MB/325/2006 H1N2 to induce immunity against heterologous highly pathogenic avian influenza (HPAI A/chicken/Vietnam/14/2005 H5N1. H1N1 and H1N2 replicated in chickens but did not cause clinical disease. Following infection, chickens developed nucleoprotein and H1 specific antibodies, and reduced H5N1 plaque size in vitro in the absence of H5 neutralizing antibodies at 21 days post infection (DPI. In addition, heterologous cell mediated immunity (CMI was demonstrated by antigen-specific proliferation and IFN-γ secretion in PBMCs re-stimulated with H5N1 antigen. Following H5N1 challenge of both pre-infected and naïve controls chickens housed together, all naïve chickens developed acute disease and died while H1N1 or H1N2 pre-infected chickens had reduced clinical disease and 70-80% survived. H1N1 or H1N2 pre-infected chickens were also challenged with H5N1 and naïve chickens placed in the same room one day later. All pre-infected birds were protected from H5N1 challenge but shed infectious virus to naïve contact chickens. However, disease onset, severity and mortality was reduced and delayed in the naïve contacts compared to directly inoculated naïve controls. These results indicate that prior infection with LPAI virus can generate heterologous protection against HPAI H5N1 in the absence of specific H5 antibody.

  9. Appearance of reassortant European avian-origin H1 influenza A viruses of swine in Vietnam.

    Science.gov (United States)

    Takemae, N; Nguyen, P T; Le, V T; Nguyen, T N; To, T L; Nguyen, T D; Pham, V P; Vo, H V; Le, Q V T; Do, H T; Nguyen, D T; Uchida, Y; Saito, T

    2018-03-06

    Three subtypes-H1N1, H1N2 and H3N2-of influenza A viruses of swine (IAVs-S) are currently endemic in swine worldwide, but there is considerable genotypic diversity among each subtype and limited geographical distribution. Through IAVs-S monitoring in Vietnam, two H1N2 influenza A viruses were isolated from healthy pigs in Ba Ria-Vung Tau Province, Southern Vietnam, on 2 December 2016. BLAST and phylogenetic analyses revealed that their HA and NA genes were derived from those of European avian-like H1N2 IAVs-S that contained avian-origin H1 and human-like N2 genes, and were particularly closely related to those of IAVs-S circulating in the Netherlands, Germany or Denmark. In addition, the internal genes of these Vietnamese isolates were derived from human A(H1N1)pdm09 viruses, suggesting that the Vietnamese H1N2 IAVs-S are reassortants between European H1N2 IAVs-S and human A(H1N1)pdm09v. The appearance of European avian-like H1N2 IAVs-S in Vietnam marks their first transmission outside Europe. Our results and statistical analyses of the number of live pigs imported into Vietnam suggest that the European avian-like H1N2 IAVs-S may have been introduced into Vietnam with their hosts through international trade. These findings highlight the importance of quarantining imported pigs to impede the introduction of new IAVs-S. © 2018 Blackwell Verlag GmbH.

  10. Predictors of H1N1 influenza in the emergency department: proposition for a modified H1N1 case definition.

    Science.gov (United States)

    Flick, H; Drescher, M; Prattes, J; Tovilo, K; Kessler, H H; Vander, K; Seeber, K; Palfner, M; Raggam, R B; Avian, A; Krause, R; Hoenigl, M

    2014-02-01

    Reliable and rapid diagnosis of influenza A H1N1 is essential to initiate appropriate antiviral therapy and preventive measures. We analysed the differences in clinical presentation and laboratory parameters between emergency department patients with PCR-confirmed H1N1 influenza infection (n = 199) and those with PCR-negative influenza-like illness (ILI; n = 252). Cough, wheezing, leucopenia, eosinopenia and a lower C-reactive protein remained significant predictors of H1N1 influenza. Proposed combinations of clinical symptoms with simple laboratory parameters (e.g. reported or measured fever and either cough or leucocytes definitions that use clinical criteria alone. © 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.

  11. Neutron detector

    Science.gov (United States)

    Stephan, Andrew C [Knoxville, TN; Jardret,; Vincent, D [Powell, TN

    2011-04-05

    A neutron detector has a volume of neutron moderating material and a plurality of individual neutron sensing elements dispersed at selected locations throughout the moderator, and particularly arranged so that some of the detecting elements are closer to the surface of the moderator assembly and others are more deeply embedded. The arrangement captures some thermalized neutrons that might otherwise be scattered away from a single, centrally located detector element. Different geometrical arrangements may be used while preserving its fundamental characteristics. Different types of neutron sensing elements may be used, which may operate on any of a number of physical principles to perform the function of sensing a neutron, either by a capture or a scattering reaction, and converting that reaction to a detectable signal. High detection efficiency, an ability to acquire spectral information, and directional sensitivity may be obtained.

  12. Ionization detector

    Energy Technology Data Exchange (ETDEWEB)

    Solomon, E E

    1976-02-27

    This invention concerns a fire detection system making use of a beta source. The ionisation detector includes a first and second chamber respectively comprising a first and second electrode, preferably a plate, with a common electrode separating the first and second chamber. Communication is provided between these chambers through a set of orifices and each chamber also has a set of orifices for communication with the ambient atmosphere. One or both chambers can comprise a particle source, preferably beta. The detector also has an adjustable electrode housed in one of the chambers to regulate the voltage between the fixed electrode of this chamber and the common electrode located between the chambers. The electrodes of the structure are connected to a detection circuit that spots a change in the ionisation current when a fire alarm condition arises. The detection circuit of a new type includes a relaxation oscillator with a programmable unijunction transistor and a light emitting diode.

  13. MUST detector

    International Nuclear Information System (INIS)

    Blumenfeld, Y.; Auger, F.; Sauvestre, J.E.

    1999-01-01

    The IPN-Orsay, in collaboration with the SPhN-Saclay and the DPTA Bruyeres, has built an array of 8 telescopes based on Si-strip technology for the study of direct reactions induced by radioactive beams. The detectors are described, along with the compact high density VXI electronics and the stand-alone data acquisition system developed in the laboratory. One telescope was tested using an 40 Ar beam and the measured performances are discussed. (authors)

  14. Radiation detector

    Energy Technology Data Exchange (ETDEWEB)

    Ohata, Shuichi; Takeuchi, Yoji

    1968-10-30

    Herein disclosed is an ionization chamber the airtightness of which can be readily tested. The ionization chamber is characterized in that a small amount of helium gas is filled in the chamber in combination with other ionization gases such as argon gas, xenon gas and the like. Helium leakage from the chamber is measured by a known helium gas sensor in a vacuum vessel. Hence the long term drift of the radiation detector sensitivity may be determined.

  15. Supply of neuraminidase inhibitors related to reduced influenza A (H1N1) mortality during the 2009-2010 H1N1 pandemic: an ecological study.

    Science.gov (United States)

    Miller, Paula E; Rambachan, Aksharananda; Hubbard, Roderick J; Li, Jiabai; Meyer, Alison E; Stephens, Peter; Mounts, Anthony W; Rolfes, Melissa A; Penn, Charles R

    2012-01-01

    The influenza A (H1N1) pandemic swept across the globe from April 2009 to August 2010 affecting millions. Many WHO Member States relied on antiviral drugs, specifically neuraminidase inhibitors (NAIs) oseltamivir and zanamivir, to treat influenza patients in critical condition. Such drugs have been found to be effective in reducing severity and duration of influenza illness, and likely reduced morbidity during the pandemic. However, it is less clear whether NAIs used during the pandemic reduced H1N1 mortality. Country-level data on supply of oseltamivir and zanamivir were used to predict H1N1 mortality (per 100,000 people) from July 2009 to August 2010 in forty-two WHO Member States. Poisson regression was used to model the association between NAI supply and H1N1 mortality, with adjustment for economic, demographic, and health-related confounders. After adjustment for potential confounders, each 10% increase in kilograms of oseltamivir, per 100,000 people, was associated with a 1.6% reduction in H1N1 mortality over the pandemic period (relative rate (RR) = 0.84 per log increase in oseltamivir supply). While the supply of zanamivir was considerably less than that of oseltamivir in each Member State, each 10% increase in kilogram of active zanamivir, per 100,000, was associated with a 0.3% reduction in H1N1 mortality (RR = 0.97 per log increase). While there are limitations to the ecologic nature of these data, this analysis offers evidence of a protective relationship between antiviral drug supply and influenza mortality and supports a role for influenza antiviral use in future pandemics.

  16. Ce que nous faisons | Page 10 | CRDI - Centre de recherches pour ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le CRDI finance des études de recherche dans les pays en voie de ... Coopération internationale ... Les conseils subventionnaires de la recherche scientifique sont essentiels au financement et à la promotion de la recherche et de l'innovation. ... Après plus d'un demisiècle de conflit, la signature d'un accord définitif de ...

  17. : tous les projets | Page 150 | CRDI - Centre de recherches pour le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Forum de recherche économique - Financement de base 2012-2014. Projet. Le Forum de recherche économique (ERF) est un réseau régional de recherche économique établi au Caire, qui compte 269 chercheurs affiliés. Date de début : 22 janvier 2013. End Date: 22 janvier 2016. Sujet: MIDDLE EAST, NORTH AFRICA, ...

  18. H1N1 Flu & U.S. Schools: Answers to Frequently Asked Questions

    Science.gov (United States)

    US Department of Education, 2009

    2009-01-01

    A severe form of influenza known as H1N1, commonly being called swine flu, has health officials around the world concerned. In the United States, the outbreak of H1N1 has prompted school closures and cancellation of school-related events. As the flu spreads, the Department of Education encourages school leaders, parents and students to know how to…

  19. Outcomes of Oseltamivir Treatment for H1N1 Infection During Pregnancy: A Retrospective Study

    Directory of Open Access Journals (Sweden)

    Nermin Akdemir

    2011-04-01

    CONCLUSION: In this retrospective, study, we found that, H1N1 infection during pregnancy has a good prognosis and without complication for maternal health. Although oseltamivir therapy is safe in pregnant women, it can be associated with cardiac structural cardiac malformations in H1N1 infected pregnancy newborns

  20. Digested Ara h 1 Loses Sensitizing Capacity When Separated into Fractions

    DEFF Research Database (Denmark)

    Bøgh, Katrine Lindholm; Barkholt, Vibeke; Rigby, Neil M.

    2012-01-01

    The major peanut allergen Ara h 1 is an easily digestible protein under physiological conditions. The present study revealed that pepsin digestion products of Ara h 1 retained the sensitizing potential in a Brown Norway rat model, while this sensitizing capacity was lost by separating the digest...

  1. Novel reassortant of swine influenza H1N2 virus in Germany.

    Science.gov (United States)

    Zell, Roland; Motzke, Susann; Krumbholz, Andi; Wutzler, Peter; Herwig, Volker; Dürrwald, Ralf

    2008-01-01

    European porcine H1N2 influenza viruses arose after multiple reassortment steps involving a porcine influenza virus with avian-influenza-like internal segments and human H1N1 and H3N2 viruses in 1994. In Germany, H1N2 swine influenza viruses first appeared in 2000. Two German H1N2 swine influenza virus strains isolated from pigs with clinical symptoms of influenza are described. They were characterized by the neutralization test, haemagglutination inhibition (HI) test and complete sequencing of the viral genomes. The data demonstrate that these viruses represent a novel H1N2 reassortant. The viruses showed limited neutralization by sera raised against heterologous A/sw/Bakum/1,832/00-like H1N2 viruses. Sera pools from recovered pigs showed a considerably lower HI reaction, indicative of diagnostic difficulties in using the HI test to detect these viruses with A/sw/Bakum/1,832/00-like H1N2 antigens. Genome sequencing revealed the novel combination of the human-like HAH1 gene of European porcine H1N2 influenza viruses and the NAN2 gene of European porcine H3N2 viruses.

  2. A historical perspective of influenza A(H1N2) virus.

    Science.gov (United States)

    Komadina, Naomi; McVernon, Jodie; Hall, Robert; Leder, Karin

    2014-01-01

    The emergence and transition to pandemic status of the influenza A(H1N1)A(H1N1)pdm09) virus in 2009 illustrated the potential for previously circulating human viruses to re-emerge in humans and cause a pandemic after decades of circulating among animals. Within a short time of the initial emergence of A(H1N1)pdm09 virus, novel reassortants were isolated from swine. In late 2011, a variant (v) H3N2 subtype was isolated from humans, and by 2012, the number of persons infected began to increase with limited person-to-person transmission. During 2012 in the United States, an A(H1N2)v virus was transmitted to humans from swine. During the same year, Australia recorded its first H1N2 subtype infection among swine. The A(H3N2)v and A(H1N2)v viruses contained the matrix protein from the A(H1N1)pdm09 virus, raising the possibility of increased transmissibility among humans and underscoring the potential for influenza pandemics of novel swine-origin viruses. We report on the differing histories of A(H1N2) viruses among humans and animals.

  3. Outbreak of pandemic influenza A/H1N1 2009 in Nepal.

    Science.gov (United States)

    Adhikari, Bal Ram; Shakya, Geeta; Upadhyay, Bishnu Prasad; Prakash Kc, Khagendra; Shrestha, Sirjana Devi; Dhungana, Guna Raj

    2011-03-23

    The 2009 flu pandemic is a global outbreak of a new strain of H1N1 influenza virus. Pandemic influenza A (H1N1) 2009 has posed a serious public health challenge world-wide. Nepal has started Laboratory diagnosis of Pandemic influenza A/H1N1 from mid June 2009 though active screening of febrile travellers with respiratory symptoms was started from April 27, 2009. Out of 609 collected samples, 302 (49.6%) were Universal Influenza A positive. Among the influenza A positive samples, 172(28.3%) were positive for Pandemic influenza A/H1N1 and 130 (21.3%) were Seasonal influenza A. Most of the pandemic cases (53%) were found among young people with ≤ 20 years. Case Fatality Ratio for Pandemic influenza A/H1N1 in Nepal was 1.74%. Upon Molecular characterization, all the isolated pandemic influenza A/H1N1 2009 virus found in Nepal were antigenically and genetically related to the novel influenza A/CALIFORNIA/07/2009-LIKE (H1N1)v type. The Pandemic 2009 influenza virus found in Nepal were antigenically and genetically related to the novel A/CALIFORNIA/07/2009-LIKE (H1N1)v type.

  4. Adoption of Preventive Measures and Attitudes toward the H1N1 Influenza Pandemic in Schools

    Science.gov (United States)

    Pérez, Anna; Rodríguez, Tània; López, Maria José; Continente, Xavier; Nebot, Manel

    2016-01-01

    Background: This study describes the perceived impact of H1N1 influenza and the adoption of the recommended measures to address the pandemic in schools. Methods: A cross-sectional self-reported survey was conducted in 433 schools in Barcelona addressed to the school principal or the H1N1 influenza designated person. A descriptive analysis was…

  5. Pandemic H1N1 2009 virus in Danish pigs: Diagnosis and lack of surveillance

    DEFF Research Database (Denmark)

    Larsen, Lars Erik; Nielsen, L. P.; Breum, Solvej Østergaard

    In March-April 2009, a novel pandemic H1N1 virus (H1N1v) of likely swine origin emerged in the human population globally. The first case in pigs was reported from Canada in May 2009 and presently almost all countries with pig production have reported cases. The emergence of a new influenza subtype...

  6. Safety of pandemic H1N1 vaccines in children and adolescents

    NARCIS (Netherlands)

    E.G. Wijnans (Leonoor); S. de Bie (Sandra); J.P. Dieleman (Jeanne); J. Bonhoeffer (Jan); M.C.J.M. Sturkenboom (Miriam)

    2011-01-01

    textabstractDuring the 2009 influenza A (H1N1) pandemic several pandemic H1N1 vaccines were licensed using fast track procedures, with relatively limited data on the safety in children and adolescents. Different extensive safety monitoring efforts were put in place to ensure timely detection of

  7. Hospitalizations for Pandemic (H1N1) 2009 among Maori and Pacific Islanders, New Zealand

    Science.gov (United States)

    Verrall, Ayesha; Norton, Katherine; Rooker, Serena; Dee, Stephen; Olsen, Leeanne; Tan, Chor Ee; Paull, Sharon; Allen, Richard

    2010-01-01

    Community transmission of influenza A pandemic (H1N1) 2009 was followed by high rates of hospital admissions in the Wellington region of New Zealand, particularly among Maori and Pacific Islanders. These findings may help health authorities anticipate the effects of pandemic (H1N1) 2009 in other communities. PMID:20031050

  8. Function and coding in the blowfly H1 neuron during naturalistic optic flow

    NARCIS (Netherlands)

    Hateren, J.H. van; Kern, R.; Schwerdtfeger, G.; Egelhaaf, M.

    2005-01-01

    Naturalistic stimuli, reconstructed from measured eye movements of flying blowflies, were replayed on a panoramic stimulus device. The directional movement-sensitive H1 neuron was recorded from blowflies watching these stimuli. The response of the H1 neuron is dominated by the response to fast

  9. Application of independent component analysis to H-1 MR spectroscopic imaging exams of brain tumours

    NARCIS (Netherlands)

    Szabo de Edelenyi, F.; Simonetti, A.W.; Postma, G.; Huo, R.; Buydens, L.M.C.

    2005-01-01

    The low spatial resolution of clinical H-1 MRSI leads to partial volume effects. To overcome this problem, we applied independent component analysis (ICA) on a set of H-1 MRSI exams of brain turnours. With this method, tissue types that yield statistically independent spectra can be separated. Up to

  10. Role of H1 linker histones in mammalian development and stem cell differentiation.

    Science.gov (United States)

    Pan, Chenyi; Fan, Yuhong

    2016-03-01

    H1 linker histones are key chromatin architectural proteins facilitating the formation of higher order chromatin structures. The H1 family constitutes the most heterogeneous group of histone proteins, with eleven non-allelic H1 variants in mammals. H1 variants differ in their biochemical properties and exhibit significant sequence divergence from one another, yet most of them are highly conserved during evolution from mouse to human. H1 variants are differentially regulated during development and their cellular compositions undergo dramatic changes in embryogenesis, gametogenesis, tissue maturation and cellular differentiation. As a group, H1 histones are essential for mouse development and proper stem cell differentiation. Here we summarize our current knowledge on the expression and functions of H1 variants in mammalian development and stem cell differentiation. Their diversity, sequence conservation, complex expression and distinct functions suggest that H1s mediate chromatin reprogramming and contribute to the large variations and complexity of chromatin structure and gene expression in the mammalian genome. Copyright © 2015 Elsevier B.V. All rights reserved.

  11. 78 FR 69539 - Removal of Attestation Process for Facilities Using H-1A Registered Nurses

    Science.gov (United States)

    2013-11-20

    ... of Attestation Process for Facilities Using H-1A Registered Nurses AGENCY: Employment and Training... registered nurses under the H-1A visa program. These subparts became obsolete after the authorizing statute... nonimmigrant classification exclusively for the temporary admission and employment of registered nurses, which...

  12. Influenza A(H1N1)pdm09 in critically ill children admitted to a ...

    African Journals Online (AJOL)

    tes. Fig. 1. The prevalence of seasonal and pandemic H1N1 (pH1N1) influenza A at RCWMCH and ... Full approval for the study was obtained from the Human Research ... respiratory virus infection, had not received prophylactic oseltamivir,.

  13. Age as Risk Factor for Death from Pandemic (H1N1) 2009, Chile

    Science.gov (United States)

    Dabanch, Jeannette; Nájera, Manuel; González, Claudia; Guerrero, Andrea; Olea, Andrea; Fasce, Rodrigo; Morales, Cecilia; Vega, Jeanette

    2011-01-01

    Pandemic (H1N1) 2009 affected Chile during the winter of 2009. The hospitalization rate was 0.56% overall and 3.47% for persons >60 years of age at risk for severe disease and death independent of concurrent conditions. Age >60 years was the major risk factor for death from pandemic (H1N1) 2009. PMID:21762580

  14. Outbreak of pandemic influenza A/H1N1 2009 in Nepal

    Directory of Open Access Journals (Sweden)

    Shrestha Sirjana

    2011-03-01

    Full Text Available Abstract Background The 2009 flu pandemic is a global outbreak of a new strain of H1N1 influenza virus. Pandemic influenza A (H1N1 2009 has posed a serious public health challenge world-wide. Nepal has started Laboratory diagnosis of Pandemic influenza A/H1N1 from mid June 2009 though active screening of febrile travellers with respiratory symptoms was started from April 27, 2009. Results Out of 609 collected samples, 302 (49.6% were Universal Influenza A positive. Among the influenza A positive samples, 172(28.3% were positive for Pandemic influenza A/H1N1 and 130 (21.3% were Seasonal influenza A. Most of the pandemic cases (53% were found among young people with ≤ 20 years. Case Fatality Ratio for Pandemic influenza A/H1N1 in Nepal was 1.74%. Upon Molecular characterization, all the isolated pandemic influenza A/H1N1 2009 virus found in Nepal were antigenically and genetically related to the novel influenza A/CALIFORNIA/07/2009-LIKE (H1N1v type. Conclusion The Pandemic 2009 influenza virus found in Nepal were antigenically and genetically related to the novel A/CALIFORNIA/07/2009-LIKE (H1N1v type.

  15. Study of charm and beauty production at HERA/H1 using dilepton events

    Energy Technology Data Exchange (ETDEWEB)

    Goettlich, M.

    2007-04-15

    A measurement is presented which investigates the production of charm and beauty quarks in ep collisions at a centre-of-mass energy of 318 GeV. Data taken by the H1 detector at the HERA collider in the years 1999, 2000, 2004 and 2005 are analysed. The collected data correspond to an integrated luminosity of 221.6 pb{sup -1}. This is the rst measurement of charm and beauty cross sections using HERA II data. Events with two or more jets of transverse momentum p{sub t}>5(4) GeV in the polar angular range 20 <{theta}<160 together with two leptons of transverse momentum p{sub t}>2(1) GeV in the polar angular ranges 30 <{theta}{sub 1}<130 and 20 <{theta}{sub 2}<150 , respectively, are selected. The first lepton is a muon, the second either a muon or an electron. Cross sections are measured in photoproduction, i.e. at photon virtualities Q{sup 2}<1 GeV{sup 2}, and for inelasticities 0.1H1, visible charm and beauty cross sections for the production of dijet and dilepton events are determined: {sigma}(ep{yields}ec anti cX{yields}ejj{mu}eX{sup '})=4.6{+-}1.0(stat.){+-}0.5(sys.) pb, {sigma}(ep{yields}ec anti cX{yields}ejj{mu}{mu}X{sup '})=2.7 {+-}0.9(stat.){+-}0.3(sys.) pb, {sigma}(ep{yields}eb anti bX{yields}ejj{mu}eX{sup '})=9.4{+-}1.2(stat.){+-}0.9(sys.) pb, and {sigma}(ep {yields}eb anti bX{yields}ejj{mu}{mu}X{sup '})=10.4 {+-} 1.5(stat.) {+-} 1.0(sys.) pb. To gain a deeper understanding of dilepton correlations in beauty events, differential dilepton cross sections are determined using the observable p{sub t}{sup rel} alone. The invariant mass m({mu}l), the transverse momentum p{sub t}({mu}l), the polar angle {theta}({mu}l) and the charge and angle correlation vertical

  16. Enseignement du français les apports de la recherche en linguistique

    CERN Document Server

    Avanzi, Mathieu; Corminboeuf, Gilles; Gachet, Frederic

    2014-01-01

    Cet ouvrage propose une reflexion collective sur la maniere dont l'enseignement du francais peut tirer profit (des resultats) de la recherche en linguistique. Le passage de la recherche a l'enseignement pose des questions fondamentales : comment traduire les travaux de recherche vers les contenus d'enseignement ? Comment choisir parmi les resultats de la recherche ceux qui ont vocation a etre adaptes utilement pour les besoins des apprenants ? Comment traiter le decalage souvent evoque entre le contenu des moyens d'enseignement et l'etat du savoir sur la langue ?

  17. Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication.

    Science.gov (United States)

    Holmes, J Bradley; Akman, Gokhan; Wood, Stuart R; Sakhuja, Kiran; Cerritelli, Susana M; Moss, Chloe; Bowmaker, Mark R; Jacobs, Howard T; Crouch, Robert J; Holt, Ian J

    2015-07-28

    Encoding ribonuclease H1 (RNase H1) degrades RNA hybridized to DNA, and its function is essential for mitochondrial DNA maintenance in the developing mouse. Here we define the role of RNase H1 in mitochondrial DNA replication. Analysis of replicating mitochondrial DNA in embryonic fibroblasts lacking RNase H1 reveals retention of three primers in the major noncoding region (NCR) and one at the prominent lagging-strand initiation site termed Ori-L. Primer retention does not lead immediately to depletion, as the persistent RNA is fully incorporated in mitochondrial DNA. However, the retained primers present an obstacle to the mitochondrial DNA polymerase γ in subsequent rounds of replication and lead to the catastrophic generation of a double-strand break at the origin when the resulting gapped molecules are copied. Hence, the essential role of RNase H1 in mitochondrial DNA replication is the removal of primers at the origin of replication.

  18. Charm and beauty production in D{sup *}{mu} events at H1/HERA

    Energy Technology Data Exchange (ETDEWEB)

    Lucaci-Timoce, A.I.

    2007-07-15

    Charm and beauty photoproduction is investigated with the H1 detector at HERA using events with a reconstructed D{sup *} meson and a muon. Data taken during the years 1999-2000 and 2004-2006, corresponding to a total integrated luminosity of 320 pb{sup -1}, are analysed. The D{sup *} mesons with transverse momentum p{sub t}(D{sup *})>1.5 GeV and pseudorapidity vertical stroke {eta}(D{sup *}) vertical stroke <1.5 are reconstructed via the decay channel D{sup *{+-}}{yields}D{sup (-)0}{pi}{sub s}{sup {+-}}{yields}(K{sup -+}{pi}{sup {+-}}){pi}{sub s}{sup {+-}}. In addition, muons with momentum p({mu})>2 GeV and vertical stroke {eta}({mu}) vertical stroke <1.735 are selected. With this selection, the contribution of light quark initiated events is negligible. The fractions of charm and beauty events in data are extracted exploiting the charge and azimuthal angle correlation between the D{sup *} meson and the muon. The charm and beauty cross sections were measured in photoproduction, i.e. for photon virtualities Q{sup 2}<1 GeV{sup 2}, and for inelasticities 0.05

  19. The first Swedish H1N2 swine influenza virus isolate represents an uncommon reassortant

    Directory of Open Access Journals (Sweden)

    Renström Lena HM

    2009-10-01

    Full Text Available Abstract The European swine influenza viruses (SIVs show considerable diversity comprising different types of H1N1, H3N2, and H1N2 strains. The intensifying full genome sequencing efforts reveal further reassortants within these subtypes. Here we report the identification of an uncommon reassortant variant of H1N2 subtype influenza virus isolated from a pig in a multisite herd where H1N2 swine influenza was diagnosed for the first time in Sweden during the winter of 2008-2009. The majority of the European H1N2 swine influenza viruses described so far possess haemagglutinin (HA of the human-like H1N2 SIV viruses and the neuraminidase (NA of either the European H1N2 or H3N2 SIV-like viruses. The Swedish isolate has an avian-like SIV HA and a H3N2 SIV-like NA, which is phylogenetically more closely related to H3N2 SIV NAs from isolates collected in the early '80s than to the NA of H3N2 origin of the H1N2 viruses isolated during the last decade, as depicted by some German strains, indicative of independent acquisition of the NA genes for these two types of reassortants. The internal genes proved to be entirely of avian-like SIV H1N1 origin. The prevalence of this SIV variant in pig populations needs to be determined, as well as the suitability of the routinely used laboratory reagents to analyze this strain. The description of this H1N2 SIV adds further information to influenza epidemiology and supports the necessity of surveillance for influenza viruses in pigs.

  20. The first Swedish H1N2 swine influenza virus isolate represents an uncommon reassortant.

    Science.gov (United States)

    Bálint, Adám; Metreveli, Giorgi; Widén, Frederik; Zohari, Siamak; Berg, Mikael; Isaksson, Mats; Renström, Lena Hm; Wallgren, Per; Belák, Sándor; Segall, Thomas; Kiss, István

    2009-10-28

    The European swine influenza viruses (SIVs) show considerable diversity comprising different types of H1N1, H3N2, and H1N2 strains. The intensifying full genome sequencing efforts reveal further reassortants within these subtypes. Here we report the identification of an uncommon reassortant variant of H1N2 subtype influenza virus isolated from a pig in a multisite herd where H1N2 swine influenza was diagnosed for the first time in Sweden during the winter of 2008-2009. The majority of the European H1N2 swine influenza viruses described so far possess haemagglutinin (HA) of the human-like H1N2 SIV viruses and the neuraminidase (NA) of either the European H1N2 or H3N2 SIV-like viruses. The Swedish isolate has an avian-like SIV HA and a H3N2 SIV-like NA, which is phylogenetically more closely related to H3N2 SIV NAs from isolates collected in the early '80s than to the NA of H3N2 origin of the H1N2 viruses isolated during the last decade, as depicted by some German strains, indicative of independent acquisition of the NA genes for these two types of reassortants. The internal genes proved to be entirely of avian-like SIV H1N1 origin. The prevalence of this SIV variant in pig populations needs to be determined, as well as the suitability of the routinely used laboratory reagents to analyze this strain.The description of this H1N2 SIV adds further information to influenza epidemiology and supports the necessity of surveillance for influenza viruses in pigs.