Modeling the impacts of climate change and technical progress on the wheat yield in inland China: An autoregressive distributed lag approach.

Directory of Open Access Journals (Sweden)

Shiyan Zhai

Full Text Available This study aims to evaluate the impacts of climate change and technical progress on the wheat yield per unit area from 1970 to 2014 in Henan, the largest agricultural province in China, using an autoregressive distributed lag approach. The bounded F-test for cointegration among the model variables yielded evidence of a long-run relationship among climate change, technical progress, and the wheat yield per unit area. In the long run, agricultural machinery and fertilizer use both had significantly positive impacts on the per unit area wheat yield. A 1% increase in the aggregate quantity of fertilizer use increased the wheat yield by 0.19%. Additionally, a 1% increase in machine use increased the wheat yield by 0.21%. In contrast, precipitation during the wheat growth period (from emergence to maturity, consisting of the period from last October to June led to a decrease in the wheat yield per unit area. In the short run, the coefficient of the aggregate quantity of fertilizer used was negative. Land size had a significantly positive impact on the per unit area wheat yield in the short run. There was no significant short-run or long-run impact of temperature on the wheat yield per unit area in Henan Province. The results of our analysis suggest that climate change had a weak impact on the wheat yield, while technical progress played an important role in increasing the wheat yield per unit area. The results of this study have implications for national and local agriculture policies under climate change. To design well-targeted agriculture adaptation policies for the future and to reduce the adverse effects of climate change on the wheat yield, climate change and technical progress factors should be considered simultaneously. In addition, adaptive measures associated with technical progress should be given more attention.

Directed Technical Change and Economic Growth Effects of Environmental Policy

DEFF Research Database (Denmark)

Kruse-Andersen, Peter Kjær

2016-01-01

A Schumpeterian growth model is developed to investigate how environmental policy affects economic growth when environmental policy also affects the direction of technical change. In contrast to previous models, production and pollution abatement technologies are embodied in separate intermediate...... unambiguously directs research efforts toward pollution abatement technologies and away from production technologies. This directed technical change reduces economic growth and pollution emission growth. Simulation results indicate that even large environmental policy reforms have small economic growth effects....... However, these economic growth effects have relatively large welfare effects which suggest that static models and exogenous growth models leave out an important welfare effect of environmental policy....

Linking Technical Education to Business Growth: A Case Study on Building Technical Skills in India

OpenAIRE

Basant, Rakesh; Chandra, Pankaj

2007-01-01

Education has been recognized as the most important source of competitive advantage for a nation. It is the key determinant of firm level productivity which in turn drives business growth and profitability. Technical knowledge, in particular, is required both for industrial as well as service development. Technical institutions contribute to the growth of business and industry in a variety of ways. The most influential and direct impact is through their graduates who bring in new skills and p...

Surgical resident technical skill self-evaluation: increased precision with training progression.

Science.gov (United States)

Quick, Jacob A; Kudav, Vishal; Doty, Jennifer; Crane, Megan; Bukoski, Alex D; Bennett, Bethany J; Barnes, Stephen L

2017-10-01

Surgical resident ability to accurately evaluate one's own skill level is an important part of educational growth. We aimed to determine if differences exist between self and observer technical skill evaluation of surgical residents performing a single procedure. We prospectively enrolled 14 categorical general surgery residents (six post-graduate year [PGY] 1-2, three PGY 3, and five PGY 4-5). Over a 6-month period, following each laparoscopic cholecystectomy, residents and seven faculty each completed the Objective Structured Assessment of Technical Skills (OSATS). Spearman's coefficient was calculated for three groups: senior (PGY 4-5), PGY3, and junior (PGY 1-2). Rho (ρ) values greater than 0.8 were considered well correlated. Of the 125 paired assessments (resident-faculty each evaluating the same case), 58 were completed for senior residents, 54 for PGY3 residents, and 13 for junior residents. Using the mean from all OSATS categories, trainee self-evaluations correlated well to faculty (senior ρ 0.97, PGY3 ρ 0.9, junior ρ 0.9). When specific OSATS categories were analyzed, junior residents exhibited poor correlation in categories of respect for tissue (ρ -0.5), instrument handling (ρ 0.71), operative flow (ρ 0.41), use of assistants (ρ 0.05), procedural knowledge (ρ 0.32), and overall comfort with the procedure (ρ 0.73). PGY3 residents lacked correlation in two OSATS categories, operative flow (ρ 0.7) and procedural knowledge (ρ 0.2). Senior resident self-evaluations exhibited strong correlations to observers in all areas. Surgical residents improve technical skill self-awareness with progressive training. Less-experienced trainees have a tendency to over-or-underestimate technical skill. Copyright © 2017 Elsevier Inc. All rights reserved.

Technical Progress of the New Worlds Observer Mission

Science.gov (United States)

Lo, Amy; Noecker, C.; Cash, W.; NWO Study Team

2009-01-01

We report on the technical progress of the New Worlds Observer (NWO) mission concept. NWO is a two spacecraft mission that is capable of detecting and characterizing extra-solar, terrestrial planets and planetary systems. NWO consists of an external starshade and an UV-optical space telescope, flying in tandem. The starshade is a petal-shaped, opaque screen that creates an extremely dark shadow large enough to shade the telescope aperture from the target star. The NWO team has been addressing the top technology challenges of the concept, and report here our progress. We will present the current mission configuration best suited to address Terrestrial Planet Finding requirements, and highlight the technological breakthroughs that we have achieved this year. In particular, we will report on progress made in precision deployables for the large starshade, and the trajectory & alignment control system for NWO. We will also briefly highlight advances in understanding the starshade optical performance.

Technical progress faced with the challenges of the energy sector in the future

International Nuclear Information System (INIS)

Maillard, D.

1999-01-01

The colloquium organised by the Association of Energy Economists dealing with the theme 'Technical progress faced with the challenges of the energy sector in the future' takes place against a backdrop of ever-increasing initiatives in this field, for example at the World Energy Council or the International Energy Agency Faith in technical progress is widespread but should be supported by studies without any preconceived ideas. Research and development efforts must be fully supported, and in a climate of opening markets and liberalization the public authorities have a major role to pay. Historically, the markets have always been able to meet new needs thanks to technology, but the ambitious targets that the international community has set itself regarding the emission of greenhouse gases imply technical improvements and major investments. (authors)

Evaporation by mechanical vapor recompression. Technical progress report, September 1-December 31, 1979

Energy Technology Data Exchange (ETDEWEB)

Iverson, C.H.; Coury, G.E.

1979-01-01

Progress to date in the development of a study of the application of the technologies of mechanical vapor recompression and falling film evaporators as applied to the beet sugar industry is reported. Progress is reported in the following areas: technical literature search and plant visitations of existing applications of VR/FFE.

ELEMENTS OF THE NEOCLASSICAL GROWTH THEORY

Directory of Open Access Journals (Sweden)

Florina Popa

2014-12-01

Full Text Available One of the relevant components of the contemporary economic science is the economic growth theory, the economic background of the time leading to new guidelines of the research. The neoclassical growth theory - the core of modern analysis - explains how the capital accumulation and technological changes affect the economy, significant for the analysis of the economic growth process being the Solow’s neoclassical growth model. The paper brief describes the elements of the economic growth model developed by Solow, both for the situation when it allows the explanation of extensive growth and that wherein the growth is of intensive nature, as a result of the intervention of exogenous technical progress – a determinant of factors productivity growth. It is highlighted the importance of the exogenous neoclassical model, proposed by Solow, who showed the determinant role of the technical progress in the economic growth phenomenon.

Experimental Facilities Division/User Program Division technical progress report 1999-2000

International Nuclear Information System (INIS)

2001-01-01

In October 1999, the two divisions of the Advanced Photon Source (APS), the Accelerator Systems Division (ASD) and the Experimental Facilities Division (XFD), were reorganized into four divisions (see high-level APS organizational chart, Fig. 1.1). In addition to ASD and XFD, two new divisions were created, the APS Operations Division (AOD), to oversee APS operations, and the User Program Division (UPD), to serve the APS user community by developing and maintaining the highest quality user technical and administration support. Previous XFD Progress Reports (ANL/APS/TB-30 and ANL/APS/TB-34) covered a much broader base, including APS user administrative support and what was previously XFD operations (front ends, interlocks, etc.) This Progress Report summarizes the main scientific and technical activities of XFD, and the technical support, research and development (R and D) activities of UPD from October 1998 through November 2000. The report is divided into four major sections, (1) Introduction, (2) SRI-CAT Beamlines, Technical Developments, and Scientific Applications, (3) User Technical Support, and (4) Major Plans for the Future. Sections 2 and 3 describe the technical activities and research accomplishments of the XFD and UPD personnel in supporting the synchrotron radiation instrumentation (SRI) collaborative access team (CAT) and the general APS user community. Also included in this report is a comprehensive list of publications (Appendix 1) and presentations (Appendix 2) by XFD and UPD staff during the time period covered by this report. The organization of section 2, SRI CAT Beamlines, Technical Developments, and Scientific Applications has been made along scientific techniques/disciplines and not ''geographical'' boundaries of the sectors in which the work was performed. Therefore items under the subsection X-ray Imaging and Microfocusing could have been (and were) performed on several different beamlines by staff in different divisions. The management of

Progress report for 1978-79, Technical Physics Division

International Nuclear Information System (INIS)

Gopalaraman, C.P.; Deshpande, R.Y.

1980-01-01

The research and development activities of the Technical Physics Division (TPD) of the Bhabha Atomic Research Centre, Bombay, during the calendar years 1978 and 1979 are reported. The TPD's major areas of work are electronics instrumentation, crystal technology, mass spectrometers, cryogenic equipment and vacuum equipment. Some of the major achievements are: (1) fabrication of various electronic instruments and components for the pulsed nuclear magnetic resonance spectrometers, (2) growth of large size NaI(Tl) and Ge crystals, (3) growth of CsI, KDP and arsenic selenide crystals, (4) fabrication of quadrupole mass filters and (5) fabrication of mass spectrometers for gas analysis and D/H analysis in water samples. (M.G.B.)

The effects of environmental regulation and technical progress on CO2 Kuznets curve: An evidence from China

International Nuclear Information System (INIS)

Yin, Jianhua; Zheng, Mingzheng; Chen, Jian

2015-01-01

Based on environmental Kuznets curve theory, a panel data model which takes environmental regulation and technical progress as its moderating factors was developed to analyse the institutional and technical factors that affect the path of low-carbon economic development. The results indicated that there was a CO 2 emission Kuznets curve seen in China. Environmental regulation had a significant moderating effect on the curve, and the inflection of CO 2 emissions could come substantially earlier under stricter environmental regulation. Meanwhile, the impact of technical progress on the low-carbon economic development path had a longer hysteresis effect but restrained CO 2 emission during its increasing stage and accelerated its downward trend during the decreasing stage which was conducive to emission reduction. Strict environmental regulation could force the high-carbon emitting industries to transfer from the eastern regions to the central or the western regions of China, which would make the CO 2 Kuznets curve higher in its increasing stage and lower in its decreasing stage than that under looser regulation. Furthermore, energy efficiency, energy structure, and industrial structure exerted a significant direct impact on CO 2 emissions; we should consider the above factors as essential in the quest for low-carbon economic development. - Highlights: • Estimate moderating effect of environmental regulation and technical progress on EKC. • There was a CO 2 emission Kuznets curve in effect in China. • Environmental regulation presents significant moderating effect on EKC. • Technical progress moderates the relationship between income and CO 2 emissions

ERIP invention 637. Technical progress report 2nd quarter, April 1997--June 1997

Energy Technology Data Exchange (ETDEWEB)

Thacker, G.W.

1997-07-22

This technical report describes progress in the development of the Pegasus plow, a stalk and root embedding apparatus. Prototype testing is reported, and includes the addition of precision tillage. Disease data, organic matter, and nitrogen levels results are very briefly described. Progress in marketing is also reported. Current marketing issues include test use by cotton and wheat growers, establishment of dealer relationships, incorporation of design modifications, expansion of marketing activities, and expansion of loan and lease program.

Regional technical innovation suitability and economic growth in China

NARCIS (Netherlands)

Zhou, Qing; Zhu, Dan; Brouwers-Ren, Liqin

2012-01-01

This paper aims to use quantitative method to analyse the suitability of regional technical innovation and further compare its influence to regional economic growth in China. Based on literature review, the authors develop an evaluation index system containing four aspects (namely, innovators,

Connective tissue growth factor (CTGF) and cancer progression.

Science.gov (United States)

Chu, Chia-Yu; Chang, Cheng-Chi; Prakash, Ekambaranellore; Kuo, Min-Liang

2008-11-01

Connective tissue growth factor (CTGF) is a member of the CCN family of secreted, matrix-associated proteins encoded by immediate early genes that play various roles in angiogenesis and tumor growth. CCN family proteins share uniform modular structure which mediates various cellular functions such as regulation of cell division, chemotaxis, apoptosis, adhesion, motility, angiogenesis, neoplastic transformation, and ion transport. Recently, CTGF expression has been shown to be associated with tumor development and progression. There is growing body of evidence that CTGF may regulate cancer cell migration, invasion, angiogenesis, and anoikis. In this review, we will highlight the influence of CTGF expression on the biological behavior and progression of various cancer cells, as well as its regulation on various types of protein signals and their mechanisms.

Cassini RTG Program. Monthly technical progress report, 27 November--31 December 1995

International Nuclear Information System (INIS)

1996-01-01

This monthly technical progress report provided information on the following tasks: spacecraft integration and liaison; engineering support; safety analysis; qualified unicouple fabrication; ETG fabrication, assembly, and test; ground support equipment (GSE); RTG shipping and launch support; designs, reviews, and mission applications; project management, quality assurance, and reliability, and contractor acquired government owned (CAGO) property acquisition

Impact of Environmental Regulation and Technical Progress on Industrial Carbon Productivity: An Approach Based on Proxy Measure

Directory of Open Access Journals (Sweden)

Huan Zhang

2016-08-01

Full Text Available This research aims to study the main influencing factors of China’s industrial carbon productivity by incorporating environmental regulation and technical progress into an econometric model. The paper focuses on data from 35 of China’s industrial sectors and covers the period from 2006 to 2014, in order to examine the impact of environmental regulation and technical progress on carbon productivity. Methods applied include panel fixed effect model, panel random effect model and two stage least squares with instrumental variables (IV-2SLS. The effect of environmental regulation and technical progress has industrial heterogeneity. The paper subdivides industrial sectors into capital and technology intensive, resource intensive and labor intensive sectors according to factor intensiveness. The estimation results of the subgroups have uncovered that for capital and technology intensive and resource intensive sectors, environmental regulation has a more significant impact than technical progress; while for labor intensive sectors, innovation more significantly influences carbon productivity. In addition, foreign direct investment (FDI and industrialization level facilitate improving carbon productivity for the full sample. By contrast, industrial structure inhibits the overall industrial carbon productivity. The industry-specific results indicate that for capital and technology intensive sectors, optimizing of the industrial structure can improve carbon productivity; for resource intensive sectors, FDI and energy consumption structure should be emphasized more; for labor intensive sectors, industrialization levels help enhance carbon productivity. Finally the industrial sector-specific policy suggestions are proposed.

Green and technical efficient growth in Danish fresh water aquaculture

DEFF Research Database (Denmark)

Nielsen, Rasmus

2011-01-01

growth can be achieved by introducing new environmentally friendly water purification systems in Danish fresh water aquaculture. Data Envelopment Analysis is used to investigate whether different water purification systems and farm size influence technical efficiency. The empirical results indicate...

Monitoring the Durability Performance of Concrete in Nuclear Waste Containment. Technical Progress Report No. 3

International Nuclear Information System (INIS)

Ulm, Franz-Josef

2000-01-01

OAK-B135 Monitoring the Durability Performance of Concrete in Nuclear Waste Containment. Technical Progress Report No. 3(NOTE: Part II A item 1 indicates ''PAPER'', but a report is attached electronically)

Curve progression and spinal growth in brace treated idiopathic scoliosis

NARCIS (Netherlands)

Tonseth, KA; Veldhuizen, AG; Cool, JC; van Horn, [No Value

The risk of progression of idiopathic scoliosis is correlated primarily to factors that predict potential remaining skeletal growth. The aim of the current study was to evaluate spinal growth, measured as the length of the scoliotic spine on serial longitudinal radiographs, and its relationship to

The Impact of Innovation, Firm Growth and Perceptions on Technical and Scale Efficiency

NARCIS (Netherlands)

Bremmer, J.; Oude Lansink, A.G.J.M.; Huirne, R.B.M.

2008-01-01

This paper uses a two-stage approach to analyse efficiency and productivity of Dutch glasshouse firms over the period 1991-1998. The first stages uses DEA to determine productivity growth and technical and scale efficiency; the second stage applies a TOBIT model to explain technical and scale

An endogenous growth model with embodied energy-saving technical change

International Nuclear Information System (INIS)

Van Zon, A.; Yetkiner, I. H.

2003-01-01

In this paper, we extend the Romer [Journal of Political Economy 98 (Part 2) (1990) S271] model in two ways. First we include energy consumption of intermediates. Second, intermediates become heterogeneous due to endogenous energy-saving technical change. We show that the resulting model can still generate steady state growth, but the growth rate depends negatively on the growth of real energy prices. The reason is that real energy price rises will lower the profitability of using new intermediate goods, and hence, the profitability of doing research, and therefore have a negative impact on growth. We also show that the introduction of an energy tax that is recycled in the form of an R and D subsidy may increase growth. We conclude that in order to have energy efficiency growth and output growth under rising real energy prices, a combination of R and D and energy policy is called for

Sludge Treatment Evaluation: 1992 Technical progress

International Nuclear Information System (INIS)

Silva, L.J.; Felmy, A.R.; Ding, E.R.

1993-01-01

This report documents Fiscal Year 1992 technical progress on the Sludge Treatment Evaluation Task, which is being conducted by Pacific Northwest Laboratory. The objective of this task is to develop a capability to predict the performance of pretreatment processes for mixed radioactive and hazardous waste stored at Hanford and other US Department of Energy (DOE) sites. Significant cost savings can be achieved if radionuclides and other undesirable constituents can be effectively separated from the bulk waste prior to final treatment and disposal. This work is initially focused on chemical equilibrium prediction of water washing and acid or base dissolution of Hanford single-shell tank (SST) sludges, but may also be applied to other steps in pretreatment processes or to other wastes. Although SST wastes contain many chemical species, there are relatively few constituents -- Na, Al, NO 3 , NO 2 , PO 4 , SO 4 , and F -- contained in the majority of the waste. These constituents comprise 86% and 74% of samples from B-110 and U-110 SSTS, respectively. The major radionuclides of interest (Cs, Sr, Tc, U) are present in the sludge in small molal quantities. For these constituents, and other important components that are present in small molal quantities, the specific ion-interaction terms used in the Pitzer or NRTL equations may be assumed to be zero for a first approximation. Model development can also be accelerated by considering only the acid or base conditions that apply for the key pretreatment steps. This significantly reduces the number of chemical species and chemical reactions that need to be considered. Therefore, significant progress can be made by developing all the specific ion interactions for a base model and an acid dissolution model

Sludge Treatment Evaluation: 1992 Technical progress

Energy Technology Data Exchange (ETDEWEB)

Silva, L J; Felmy, A R; Ding, E R

1993-01-01

This report documents Fiscal Year 1992 technical progress on the Sludge Treatment Evaluation Task, which is being conducted by Pacific Northwest Laboratory. The objective of this task is to develop a capability to predict the performance of pretreatment processes for mixed radioactive and hazardous waste stored at Hanford and other US Department of Energy (DOE) sites. Significant cost savings can be achieved if radionuclides and other undesirable constituents can be effectively separated from the bulk waste prior to final treatment and disposal. This work is initially focused on chemical equilibrium prediction of water washing and acid or base dissolution of Hanford single-shell tank (SST) sludges, but may also be applied to other steps in pretreatment processes or to other wastes. Although SST wastes contain many chemical species, there are relatively few constituents -- Na, Al, NO[sub 3], NO[sub 2], PO[sub 4], SO[sub 4], and F -- contained in the majority of the waste. These constituents comprise 86% and 74% of samples from B-110 and U-110 SSTS, respectively. The major radionuclides of interest (Cs, Sr, Tc, U) are present in the sludge in small molal quantities. For these constituents, and other important components that are present in small molal quantities, the specific ion-interaction terms used in the Pitzer or NRTL equations may be assumed to be zero for a first approximation. Model development can also be accelerated by considering only the acid or base conditions that apply for the key pretreatment steps. This significantly reduces the number of chemical species and chemical reactions that need to be considered. Therefore, significant progress can be made by developing all the specific ion interactions for a base model and an acid dissolution model.

Decontamination Systems Information and Research Program. Quarterly technical progress report, January 1--March 31, 1994

Energy Technology Data Exchange (ETDEWEB)

1994-05-01

West Virginia University (WVU) and the US DOE Morgantown Energy Technology Center (METC) entered into a Cooperative Agreement on August 29, 1992 entitled ``Decontamination Systems Information and Research Programs.`` Stipulated within the Agreement is the requirement that WVU submit to METC a series of Technical Progress Reports on a quarterly basis. This report comprises the first Quarterly Technical Progress Report for Year 2 of the Agreement. This report reflects the progress and/or efforts performed on the sixteen (16) technical projects encompassed by the Year 2 Agreement for the period of January 1 through March 31, 1994. In situ bioremediation of chlorinated organic solvents; Microbial enrichment for enhancing in-situ biodegradation of hazardous organic wastes; Treatment of volatile organic compounds (VOCs) using biofilters; Drain-enhanced soil flushing (DESF) for organic contaminants removal; Chemical destruction of chlorinated organic compounds; Remediation of hazardous sites with steam reforming; Soil decontamination with a packed flotation column; Use of granular activated carbon columns for the simultaneous removal of organics, heavy metals, and radionuclides; Monolayer and multilayer self-assembled polyion films for gas-phase chemical sensors; Compact mercuric iodide detector technology development; Evaluation of IR and mass spectrometric techniques for on-site monitoring of volatile organic compounds; A systematic database of the state of hazardous waste clean-up technologies; Dust control methods for insitu nuclear and hazardous waste handling; Winfield Lock and Dam remediation; and Socio-economic assessment of alternative environmental restoration technologies.

Environmental Research Division technical progress report, January 1984-December 1985

International Nuclear Information System (INIS)

1986-05-01

Technical progress in the various research and assessment activities of Argonne National Laboratory's Environmental Research Division is reported for the period 1984 to 1985. Textual, graphic, and tabular information is used to briefly summarize (in separate chapters) the work of the Division's Atmospheric Physics, Environmental Effects Research, Environmental Impacts, Fundamental Molecular Physics and Chemistry, and Waste Management Programs. Information on professional qualifications, awards, and outstanding professional activities of staff members, as well as lists of publications, oral presentations, special events organized, and participants in educational programs, are provided in appendices at the end of each chapter

Environmental Research Division technical progress report, January 1984-December 1985

Energy Technology Data Exchange (ETDEWEB)

1986-05-01

Technical progress in the various research and assessment activities of Argonne National Laboratory's Environmental Research Division is reported for the period 1984 to 1985. Textual, graphic, and tabular information is used to briefly summarize (in separate chapters) the work of the Division's Atmospheric Physics, Environmental Effects Research, Environmental Impacts, Fundamental Molecular Physics and Chemistry, and Waste Management Programs. Information on professional qualifications, awards, and outstanding professional activities of staff members, as well as lists of publications, oral presentations, special events organized, and participants in educational programs, are provided in appendices at the end of each chapter.

Institutional effectiveness of REDD+ MRV: Countries progress in implementing technical guidelines and good governance requirements

NARCIS (Netherlands)

Ochieng, R.M.; Visseren-Hamakers, Ingrid; Arts, B.; Brockhaus, M.; Herold, M.

2016-01-01

The UNFCCC requires REDD+ countries wishing to receive results-based payments to measure, report and verify (MRV) REDD+ impacts; and outlines technical guidelines and good governance requirements for MRV. This article examines institutional effectiveness of REDD+ MRV by assessing countries’ progress

International and intranational technological spillovers and productivity growth in China

OpenAIRE

Fu, Xiaolan; Gong, Yundan

2009-01-01

Technological spillovers from foreign direct investment (FDI) have been regarded as a major source of technical progress and productivity growth. This paper explores the role of international and intranational technological spillovers from FDI in technical change, efficiency improvement, and total factor productivity growth in Chinese manufacturing firms using a recent Chinese manufacturing firm-level panel data set over the 2001–05 period. International industry-specific research and develop...

Index to Nuclear Safety: a technical progress review by chrology, permuted title, and author, Volume 11(1) through Volume 20(6)

Energy Technology Data Exchange (ETDEWEB)

Cottrell, W B; Passiakos, M

1980-06-01

This index to Nuclear Safety, a bimonthly technical progress review, covers articles published in Nuclear Safety, Volume II, No. 1 (January-February 1970), through Volume 20, No. 6 (November-December 1979). It is divided into three sections: a chronological list of articles (including abstracts) followed by a permuted-title (KWIC) index and an author index. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center (NSIC), covers all safety aspects of nuclear power reactors and associated facilities. Over 600 technical articles published in Nuclear Safety in the last ten years are listed in this index.

Nonequilibrium photochemical reactions induced by lasers. Technical progress report

International Nuclear Information System (INIS)

Steinfeld, J.I.

1978-04-01

Research has progressed in six principal subject areas of interest to DOE advanced (laser) isotope separation efforts. These are (1) Infrared double resonance spectroscopy of molecules excited by multiple infrared photon absorption, particularly SF 6 and vinyl chloride. (2) Infrared multiphoton excitation of metastable triplet-state molecules, e.g., biacetyl. (3) An Information Theory analysis of multiphoton excitation and collisional deactivation has been carried out. (4) The mechanism of infrared energy deposition and multiphoton-induced reactions in chlorinated ethylene derivatives; and RRKM (statistical) model accounts for all observed behavior of the system, and a deuterium-specific reaction pathway has been identified. (5) Diffusion-enhanced laser isotope separation in N 16 O/N 18 O. (6) A technical evaluation of laser-induced chemistry and isotope separation

Productivity growth in food crop production in Imo State, Nigeria ...

African Journals Online (AJOL)

Agriculture plays pivotal roles in Nigeria including food security, employment, foreign exchange earnings and poverty reduction. This study examined the growth in food crop productivity in Imo State in Nigeria with emphasis on the decomposition of total factor productivity (TFP) into technical progress, changes in technical ...

Projects at the component development and integration facility. Quarterly technical progress report, April 1, 1994--June 30, 1994

International Nuclear Information System (INIS)

1994-01-01

This quarterly technical progress report presents progress on the projects at the Component Development and Integration Facility (CDIF) during the third quarter of FY94. The CDIF is a major Department of Energy test facility in Butte, Montana, operated by MSE, Inc. Projects in progress include: Biomass Remediation Project; Heavy Metal-Contaminated Soil Project; MHD Shutdown; Mine Waste Technology Pilot Program; Plasma Projects; Resource Recovery Project; and Spray Casting Project

Estimating and decomposing productivity growth of the electricity generation industry in Malaysia: A stochastic frontier analysis

International Nuclear Information System (INIS)

See, Kok Fong; Coelli, Tim

2013-01-01

This study examines the total factor productivity (TFP) growth of the Malaysian electricity generation industry over the 1998 to 2005 period. The stochastic frontier analysis (SFA) approach is used to measure TFP change and decompose TFP growth into efficiency change and technical progress. We find that it achieved average annual TFP growth of 2.34%, with technical change contributing the most to the TFP growth over the eight year period. We hence hypothesise that the new power plants with their newer capital-embodied technologies commencing during the sample period are likely to be the main reason for this strong technical change. In addition, it is also noted that this estimate for the Malaysian electricity generation industry is larger than the estimate obtained for the electricity sector as a whole, where we obtain 1.34% per year for a comparable period. -- Highlights: •This is the first empirical study that examines the TFP growth of the Malaysian electricity generation industry using the SFA method. •An average annual TFP change of the Malaysian electricity generation industry over eight years (1998-2005) has been achieved at 2.34% per year. •The technical progress contributing the most to the TFP growth and technical efficiency change and scale change making small contributions over the sample period

Growth rates and the prevalence and progression of scoliosis in short-statured children on Australian growth hormone treatment programmes

Directory of Open Access Journals (Sweden)

McPhee Ian

2007-02-01

Full Text Available Abstract Study design and aim This was a longitudinal chart review of a diverse group (cohort of patients undergoing HGH (Human Growth Hormone treatment. Clinical and radiological examinations were performed with the aim to identify the presence and progression of scoliosis. Methods and cohort 185 patients were recruited and a database incorporating the age at commencement, dose and frequency of growth hormone treatment and growth charts was compiled from their Medical Records. The presence of any known syndrome and the clinical presence of scoliosis were included for analysis. Subsequently, skeletally immature patients identified with scoliosis were followed up over a period of a minimum four years and the radiologic type, progression and severity (Cobb angle of scoliosis were recorded. Results Four (3.6% of the 109 with idiopathic short stature or hormone deficiency had idiopathic scoliosis (within normal limits for a control population and scoliosis progression was not prospectively observed. 13 (28.8% of 45 with Turner syndrome had scoliosis radiologically similar to idiopathic scoliosis. 11 (48% of 23 with varying syndromes, had scoliosis. In the entire cohort, the growth rates of those with and without scoliosis were not statistically different and HGH treatment was not ceased because of progression of scoliosis. Conclusion In this study, there was no evidence of HGH treatment being responsible for progression of scoliosis in a small number of non-syndromic patients (four. An incidental finding was that scoliosis, similar to the idiopathic type, appears to be more prevalent in Turner syndrome than previously believed.

Technical progress and climatic change

International Nuclear Information System (INIS)

Ausubel, J.H.

1995-01-01

The global warming debate has neglected and thus underestimated the importance of technical change in considering reduction in greenhouse gases and adaptation to climate change. Relevant quantitative cases of long-run technical change during the past 100 years are presented in computing, communications, transport, energy, and agriculture. A noteworthy technological trajectory is that of decarbonization, or decreasing carbon intensity of primary energy. If human societies have not yet reached the end of the history of technology, the cost structure for mitigation and adaptation changes could be cheap. (Author)

Western Research Institute: Annual technical progress report, October 1987--September 1988

Energy Technology Data Exchange (ETDEWEB)

1988-12-01

This report describes the technical progress made by the Western Research Institute of the University of Wyoming Research Institute of the University of Wyoming Research Corporation on work performed for the period October 1, 1987 through September 30, 1988. This research involves five resource areas: oil shale, tar sand, underground coal gasification, advanced process technology, and advanced fuels research. Under the terms of the cooperative agreement, an annual project plan has been approved by DOE. The work reported herein reflects the implementation of the research in the plan and follows the structure used therein. 49 refs., 32 figs., 87 tabs.

Regulatory design governing progression of population growth phases in bacteria.

Directory of Open Access Journals (Sweden)

Agustino Martínez-Antonio

Full Text Available It has long been noted that batch cultures inoculated with resting bacteria exhibit a progression of growth phases traditionally labeled lag, exponential, pre-stationary and stationary. However, a detailed molecular description of the mechanisms controlling the transitions between these phases is lacking. A core circuit, formed by a subset of regulatory interactions involving five global transcription factors (FIS, HNS, IHF, RpoS and GadX, has been identified by correlating information from the well- established transcriptional regulatory network of Escherichia coli and genome-wide expression data from cultures in these different growth phases. We propose a functional role for this circuit in controlling progression through these phases. Two alternative hypotheses for controlling the transition between the growth phases are first, a continuous graded adjustment to changing environmental conditions, and second, a discontinuous hysteretic switch at critical thresholds between growth phases. We formulate a simple mathematical model of the core circuit, consisting of differential equations based on the power-law formalism, and show by mathematical and computer-assisted analysis that there are critical conditions among the parameters of the model that can lead to hysteretic switch behavior, which--if validated experimentally--would suggest that the transitions between different growth phases might be analogous to cellular differentiation. Based on these provocative results, we propose experiments to test the alternative hypotheses.

Regulatory design governing progression of population growth phases in bacteria.

Science.gov (United States)

Martínez-Antonio, Agustino; Lomnitz, Jason G; Sandoval, Santiago; Aldana, Maximino; Savageau, Michael A

2012-01-01

It has long been noted that batch cultures inoculated with resting bacteria exhibit a progression of growth phases traditionally labeled lag, exponential, pre-stationary and stationary. However, a detailed molecular description of the mechanisms controlling the transitions between these phases is lacking. A core circuit, formed by a subset of regulatory interactions involving five global transcription factors (FIS, HNS, IHF, RpoS and GadX), has been identified by correlating information from the well- established transcriptional regulatory network of Escherichia coli and genome-wide expression data from cultures in these different growth phases. We propose a functional role for this circuit in controlling progression through these phases. Two alternative hypotheses for controlling the transition between the growth phases are first, a continuous graded adjustment to changing environmental conditions, and second, a discontinuous hysteretic switch at critical thresholds between growth phases. We formulate a simple mathematical model of the core circuit, consisting of differential equations based on the power-law formalism, and show by mathematical and computer-assisted analysis that there are critical conditions among the parameters of the model that can lead to hysteretic switch behavior, which--if validated experimentally--would suggest that the transitions between different growth phases might be analogous to cellular differentiation. Based on these provocative results, we propose experiments to test the alternative hypotheses.

Technical meeting on progress in managing, and limiting the consequences of events exceeding the design basis

International Nuclear Information System (INIS)

Fabian, H.

2004-01-01

The Technical Groups on 'Reactor Safety' and 'Thermodynamics and Fluid Dynamics' of the Kerntechnische Gesellschaft e.V. organized a joint technical meeting on 'Progress in Managing, and Limiting the Consequences of, Events Exceeding the Design Basis' at the FTU Training Center of the Karlsruhe Research Center. The topic chosen, the papers presented, the presenters, and the non-technical part of the program met with lively interest on the part of institutions in the nuclear field. These were the objectives of the technical meeting: - Establishing a forum for communicating relevant topics. - In-depth discussion of the main topic, i.e. the advanced development of reactor safety, research in the field, and its application, in twenty selected papers presented by speakers from different institutions. - Presentation of topical work in a nuclear technology institution, the Karlsruhe Research Center. (orig.) [de

Studies in theoretical high energy particle physics: Technical progress report [February 1987-February 1988

International Nuclear Information System (INIS)

Sukhatme, U.P.; Keung, Wai-Yee; Kovacs, E.

1988-02-01

This is a technical progress report for grant No. FG02-84ER40173 for the period February 1987 to February 1988. Our research on supersymmetric quantum mechanics has yielded many interesting results. In particular, a systematic approach to the tunneling problem in double well potentials has been developed. Higgs boson related physics at the high energy hadron colliders has been extensively studied

Accelerator research studies. Technical progress report, July 1, 1985-June 30, 1986

International Nuclear Information System (INIS)

1986-01-01

Progress is reported in these areas: study of instabilities and emittance growth in periodic focusing systems for intense beams; study of collective ion acceleration by intense electron beams and pulse powered plasma focus; and study of microwave sources and parameter scaling for high-frequency linacs

The role of technical progress in the process of recalculating oil reserves; Le role du progres technique dans le processus de renouvellement des reserves petrolieres

Energy Technology Data Exchange (ETDEWEB)

Boulard, J.N. [Total/Fina/Institut Francais du Petrole (IFP), 92 - Rueil-Malmaison (France)

1999-08-01

Contrary to the concept of resources (which is essentially a geological one), the notion of reserves designates the quantities that are technically and economically recoverable. Beyond the production-related effect, the reserves therefore evolve over time in accordance with numerous technical and economic parameters. Among these parameters, it can be seen that technical progress plays a considerable role throughout the process of converting resources into reserves, including progress in the identification, accessibility and processing of the resources, and improvements in economic viability. After having tackled the problem of measuring the 'technical progress effects' and citing examples, we demonstrate that the evolution in oil reserves is subject to three types of impact. These are a quantitative impact by significantly improving the recovery rates or making it possible to identify hitherto undetectable oil fields, a qualitative impact by widening the resource base thanks to the adoption of new categories of oil (in particular the so-called 'unconventional' oils) and by carrying out the gradual substitution between these resources of differing qualities. There is also a dynamic impact, through the acceleration of resource availability. Through these three approaches, technical progress makes makes it possible to ensure continuity in oil supply and contributes significantly to the recalculation of reserves. It therefore acts as a compensating factor, counterbalancing the progressive depletion of resources. (author)

Amarillo National Resource Center for Plutonium. Quarterly technical progress report, May 1--July 31, 1998

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-09-01

Progress is reported on research projects related to the following: Electronic resource library; Environment, safety, and health; Communication, education, training, and community involvement; Nuclear and other materials; and Reporting, evaluation, monitoring, and administration. Technical studies investigate remedial action of high explosives-contaminated lands, radioactive waste management, nondestructive assay methods, and plutonium processing, handling, and storage.

GPHS-RTGs in support of the Cassini RTG Program. Semi annual technical progress report, September 26, 1994--April 2, 1995

International Nuclear Information System (INIS)

1995-01-01

The technical progress achieved during the period 26 September 1994 through 2 April 1995 on Contract DE-AC03-91SF18852 Radioisotope Thermoelectric Generators and Ancillary Activities is described herein. Monthly technical activity for the period 27 February 1995 through 2 April 1995 is included in this progress report. The report addresses tasks, including: spacecraft integration and liaison; engineering support; safety; qualified unicouple production; ETG Fabrication, assembly, and test; ground support equipment; RTG shipping and launch support; designs, reviews, and mission applications; project management, quality assurance, reliability, contract changes, CAGO acquisition (operating funds), and CAGO maintenance and repair; and CAGO acquisition (capital funds)

Fiscal Deficit, National Saving and Sustainability of Economic Growth in Emerging Economies: A Dynamic GMM Panel Data Approach

Directory of Open Access Journals (Sweden)

Buscemi Antonino

2012-01-01

Full Text Available The neoclassical growth models argued that the movement to steady states; technology, exogenous rate of savings, population growth and technical progress stimulate higher growth levels (Solow 1956. Contrary to the neoclassical argument, endogenous growth model argues that, in the theory of endogenous growth, government play a significant role in promoting accumulation of knowledge, research and development, public investment, human capital development, law and order can generate growth both in the short and long run. Moreover, they assumed technical progress as endogenous variable for growth (Barro 1995. This study analyze the effects of fiscal deficit on sustainability of economic growth and provided new empirical evidence on the effects of fiscal deficit on saving and sustainability of economic growth based on the assumption of endogenous growth model. We estimated using the reduced form of GMM method for dynamic panels covers 1990-2009 for three emerging countries that includes China, India and South Africa.

Labor Productivity Growth, Education, Health and Technological Progress: A Cross-Country Analysis

OpenAIRE

Supachet Chansarn

2010-01-01

This study aims to calculate the growth rates of labor productivity of 30 countries categorized into four groups, including G7 countries, western developed countries, eastern developed countries and eastern developing countries, during 1981 – 2005 and examine the influences of education, health and technological progress on the growth rate of labor productivity. The findings reveal that the growth rates of labor productivity of every country, except the Philippines, were greater than four per...

Works Technical Department progress report, March 1961

Energy Technology Data Exchange (ETDEWEB)

None

1961-04-19

This document details the activities of the Savannah River Works Technical Department during the month of March 1961. Topics discussed are: Reactor Technology, Separations Technology, Engineering Assistance, Health Physics, Laboratories Overview, and Technical Papers Issued.

Numerical study of how creep and progressive stiffening affect the growth stress formation in trees

DEFF Research Database (Denmark)

Ormarsson, Sigurdur; Dahlblom, O.; Johansson, M.

2010-01-01

It is not fully understood how much growth stresses affect the final quality of solid timber products in terms of e.g. shape stability. It is for example difficult to predict the internal growth stress field within the tree stem. Growth stresses are progressively generated during the tree growth...... and they are highly influenced by climate, biologic and material related factors. To increase the knowledge of the stress formation a finite element model was created to study how the growth stresses develop during the tree growth. The model is an axisymmetric general plane strain model where material for all new...... annual rings is progressively added to the tree during the analysis. The material model used is based on the theory of small strains (where strains refer to the undeformed configuration which is good approximation for strains less than 4%) where so-called biological maturation strains (growth...

Targeting fibroblast growth factor receptor signaling inhibits prostate cancer progression.

Science.gov (United States)

Feng, Shu; Shao, Longjiang; Yu, Wendong; Gavine, Paul; Ittmann, Michael

2012-07-15

Extensive correlative studies in human prostate cancer as well as studies in vitro and in mouse models indicate that fibroblast growth factor receptor (FGFR) signaling plays an important role in prostate cancer progression. In this study, we used a probe compound for an FGFR inhibitor, which potently inhibits FGFR-1-3 and significantly inhibits FGFR-4. The purpose of this study is to determine whether targeting FGFR signaling from all four FGFRs will have in vitro activities consistent with inhibition of tumor progression and will inhibit tumor progression in vivo. Effects of AZ8010 on FGFR signaling and invasion were analyzed using immortalized normal prostate epithelial (PNT1a) cells and PNT1a overexpressing FGFR-1 or FGFR-4. The effect of AZ8010 on invasion and proliferation in vitro was also evaluated in prostate cancer cell lines. Finally, the impact of AZ8010 on tumor progression in vivo was evaluated using a VCaP xenograft model. AZ8010 completely inhibits FGFR-1 and significantly inhibits FGFR-4 signaling at 100 nmol/L, which is an achievable in vivo concentration. This results in marked inhibition of extracellular signal-regulated kinase (ERK) phosphorylation and invasion in PNT1a cells expressing FGFR-1 and FGFR-4 and all prostate cancer cell lines tested. Treatment in vivo completely inhibited VCaP tumor growth and significantly inhibited angiogenesis and proliferation and increased cell death in treated tumors. This was associated with marked inhibition of ERK phosphorylation in treated tumors. Targeting FGFR signaling is a promising new approach to treating aggressive prostate cancer.

Nuclear structure theory. Annual technical progress report, October 1, 1976--September 30, 1977

International Nuclear Information System (INIS)

French, J.B.; Koltun, D.S.

1977-01-01

This report summarizes progress during the past year in the following areas of nuclear structure and reaction theory: (1) statistical spectroscopy, including giant resonances for beta and electromagnetic excitation and sum rules (including inverse-energy-weighted sum rules), statistical methods of truncating shell model spaces and renormalization of operators, study of state labelling and ''chains'' of groups, evaluation of fluctuation measures, technical aspects of operator averaging; (2) meson interactions with nuclei, including scattering and absorption of mesons by nuclei (general methods), models for absorption, single- and double-charge exchange of pions, role of rho mesons

FY 1992 work plan and technical progress reports

Energy Technology Data Exchange (ETDEWEB)

NONE

1992-11-01

The Desert Research Institute (DRI) is a division of the University of Nevada System devoted to multidisciplinary scientific research. For more than 25 years, DRI has conducted research for the US Department of Energy`s Nevada Field Office (DOE/NV) in support of operations at the Nevada Test Site (NTS). During that time, the research program has grown from an early focus on hydrologic studies to include the areas of geology, archaeology, environmental compliance and monitoring, statistics, database management, public education, and community relations. The range of DRI`s activities has also expanded to include a considerable amount of management and administrative support in addition to scientific investigations. DRI`s work plan for FY 1992 reflects a changing emphasis in DOE/NV activities from nuclear weapons testing to environmental restoration and monitoring. Most of the environmental projects from FY 1991 are continuing, and several new projects have been added to the Environmental Compliance Program. The Office of Technology Development Program, created during FY 1991, also includes a number of environmental projects. This document contains the FY 1992 work plan and quarterly technical progress reports for each DRI project.

Final Technical Progress Report: Development of Low-Cost Suspension Heliostat; December 7, 2011 - December 6, 2012

Energy Technology Data Exchange (ETDEWEB)

Bender, W.

2013-01-01

Final technical progress report of SunShot Incubator Solaflect Energy. The project succeeded in demonstrating that the Solaflect Suspension Heliostat design is viable for large-scale CSP installations. Canting accuracy is acceptable and is continually improving as Solaflect improves its understanding of this design. Cost reduction initiatives were successful, and there are still many opportunities for further development and further cost reduction.

Scientific progress as increasing verisimilitude.

Science.gov (United States)

Niiniluoto, Ilkka

2014-06-01

According to the foundationalist picture, shared by many rationalists and positivist empiricists, science makes cognitive progress by accumulating justified truths. Fallibilists, who point out that complete certainty cannot be achieved in empirical science, can still argue that even successions of false theories may progress toward the truth. This proposal was supported by Karl Popper with his notion of truthlikeness or verisimilitude. Popper's own technical definition failed, but the idea that scientific progress means increasing truthlikeness can be expressed by defining degrees of truthlikeness in terms of similarities between states of affairs. This paper defends the verisimilitude approach against Alexander Bird who argues that the "semantic" definition (in terms of truth or truthlikeness alone) is not sufficient to define progress, but the "epistemic" definition referring to justification and knowledge is more adequate. Here Bird ignores the crucial distinction between real progress and estimated progress, explicated by the difference between absolute (and usually unknown) degrees of truthlikeness and their evidence-relative expected values. Further, it is argued that Bird's idea of returning to the cumulative model of growth requires an implausible trick of transforming past false theories into true ones.

Combined macroscopic and microscopic approach to the fracture of metals. Technical progress report

International Nuclear Information System (INIS)

Asaro, R.J.; Gurland, J.; Needleman, A.; Rice, R.J.

1979-06-01

Progress is reported on microscopic fracture mechanisms, including studies of void and crack initiation in steels in the absence and presence of hydrogen, the effects of hydrogen on ductile fracture in medium and high carbon steels; elastic--plastic crack growth including the quasi-stable growth of cracks in ductile solids under increasing load and conditions of instability; and elevated temperature rupture including analysis of the stress field near a crack tip in an elastic-nonlinear viscous material under tensile load as well as the processes of diffusion, and cavitation of grain boundaries in plastically creeping materials

Generation and focusing of pulsed intense ion beams. Technical progress report, 20 August 1981-30 September 1982

International Nuclear Information System (INIS)

Hammer, D.A.; Kusse, B.R.; Sudan, R.N.

1983-07-01

The progress on this contract is described in two parts. The first deals with the technical operation of the LION accelerator which is the exact equivalent to one line of PBFA-I. The second part is concerned with the experimental results on the ion diode mounted at the front end of the LION accelerator

Strategy of technical innovation

International Nuclear Information System (INIS)

Lee, Ga Jong

1990-12-01

This book deals with policy of scientific technique and technical innovation such as research for development and types of technical innovation, historical development and process of technical innovation, economic growth, technology change and investment for research and development, structure and form of technical transfer with the meaning process, from, structure and theory, economic growth and investment of research and development with experiential analysis and case study on strategy of technical innovation in electron and fine chemical industry.

Some Approaches to the Accounting and Analysis of the Impact of Scientific and Technological Progress in the Harrod-Domar Economic Growth Model

Directory of Open Access Journals (Sweden)

Dilenko Viktor O.

2016-11-01

Full Text Available The paper presents methods for the accounting of autonomous and induced scientific and technological progress in the Harrod-Domar model of economic dynamics that imply determining the incremental capital/output ratio of the model in the form of special functions of time. As part of the received version of the Harrod-Domar model, on the basis of conditional data there conducted a numerical study of some aspects of the impact of parameters of scientific and technological progress and the initial state of the economy being modeled on peculiarities of corresponding trajectories of its dynamics. A simple economic and mathematical problem of determining an optimal value of investments in the implementation of the induced STP is formulated, and content interpretation of the obtained solution is carried out. Possible directions of development of the obtained results may be associated with the application of the proposed modification of the Harrod-Domar model to build and analyze mathematical models of optimal economic growth in view of the induced STP, as well as with the prospective use of these results to improve dynamic models of the Leontief type in terms of considering innovation processes (scientific and technical progress of various kinds.

The U.S. nuclear waste management program - technical progress at Yucca Mountain

Energy Technology Data Exchange (ETDEWEB)

Barrett, L.H. [U.S. Department of Energy (United States)

2001-07-01

This paper discusses the current status of a national program being developed by the U.S. Department of Energy for the management of spent nuclear fuel and high-level radioactive waste produced by civilian nuclear power generation and defense-related activities. In 1987 the U.S. Congress directed the Department to characterize the Yucca Mountain site in Nevada and determine its suitability for development of a geologic repository. This paper will focus on the technical progress that has been made after more than 15 years of scientific and engineering investigations at Yucca Mountain, and the remaining work that is being done to support a decision on whether to recommend the site for development of a geologic repository. (author)

The Model of Optimum Economic Growth with the Induced Scientific-Technological Progress

Directory of Open Access Journals (Sweden)

Dilenko Viktor A.

2017-07-01

Full Text Available On the basis of the economic dynamics of the Harrod – Domar model, a model of optimum economic growth in line with the induced scientific-technological progress (STP has been built. In order to reflect the induced scientific-technological progress, with this model is proposed to further allocate the income element that is specially used for the investment of innovation activity, implementation of which reduces the capital intensity in development of the discussed economy. For the simplest way of presenting an economic mechanism for the investment of induced STP, analytical solutions of an appropriate task in optimum management have been obtained. Studying these decisions allowed to reveal the characteristics of the impact of parameters of scientific-technological progress and the analyzed economic system on choosing the best trajectory for its evolution. Possible directions for further developing the results presented can be considered the tasks in building and analyzing models of optimum economic growth that implement different investment options for the induced STP, as well as the models in which this investment mechanism is not exogenouslyed, but rather the result of the corresponding economic-mathematical research.

Habit formation, work ethics, and technological progress

OpenAIRE

Faria, João Ricardo; León-Ledesma, Miguel A.

2002-01-01

Work ethics affects labor supply. This idea is modeled assuming that work is habit forming. This paper introduces working habits in a neoclassical growth model and compares its outcomes with a model without habit formation. In addition, it analyzes the impact of different forms of technical progress. The findings are that i) labor supply in the habit formation case is higher than in the neoclassical case; ii) unlike in the neoclassical case, labor supply in the presence of habit formation wil...

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Kindergarten. Technical Report # 0921

Science.gov (United States)

Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in kindergarten. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2008 and administered to approximately 2800 students from…

The neoclassical theory of growth and distribution

Directory of Open Access Journals (Sweden)

Robert M. Solow

2000-12-01

Full Text Available The paper surveys the neoclassical theory of growth. As a preliminary, the meaning of the adjective "neoclassical" is discussed. The basic model is then sketched, and the conditions ensuring a stationary state are illustrated. The issue of the convergence to a stationary state (and that of the speed of convergence is further considered. A discussion of "primary factors" opens the way to the "new" theory of growth, with endogenous technical progress. A number of extensions of the basic model are then recalled: two-sector and multi-sectoral models, overlapping generations models, the role of money in growth models.

Decontamination Systems Information and Research Program. Quarterly technical progress report, January 1--March 31, 1993

Energy Technology Data Exchange (ETDEWEB)

1993-04-01

This reports reports the progress/efforts performed on six technical projects: 1. systematic assessment of the state of hazardous waste clean-up technologies; 2. site remediation technologies (SRT):drain- enhanced soil flushing for organic contaminants removal; 3. SRT: in situ bio-remediation of organic contaminants; 4. excavation systems for hazardous waste sites: dust control methods for in-situ nuclear waste handling; 5. chemical destruction of polychlorinated biphenyls; and 6. development of organic sensors: monolayer and multilayer self-assembled films for chemical sensors.

Fibroblast growth factor-2-induced host stroma reaction during initial tumor growth promotes progression of mouse melanoma via vascular endothelial growth factor A-dependent neovascularization.

Science.gov (United States)

Tsunoda, Satoshi; Nakamura, Toshiyuki; Sakurai, Hiroaki; Saiki, Ikuo

2007-04-01

Fibroblast growth factor (FGF)-2 has been considered to play a critical role in neovascularization in several tumors; however, its precise role in tumor progression is not fully understood. In the present study, we have characterized the role of FGF-2 in B16-BL6 mouse melanoma cells, focusing on effects during the initial phase of tumor growth. FGF-2 was injected at the tumor inoculation site of dorsal skin during the initial phase. FGF-2 induced marked tumor growth and lymph node metastasis. This was well correlated with an increase in neovascularization in the host stroma. FGF-2 also recruited inflammatory and mesenchymal cells in host stroma. Marked tumor growth, pulmonary metastasis and intensive neovascularization in tumor parenchyma were also observed after a single injection of FGF-2 into the footpad inoculation site. In contrast, repeated injections of FGF-2 at a site remote from the footpad tumor were ineffective in promoting tumor growth and metastasis. These promoting activities of FGF-2 were blocked by local injections of a glucocorticoid hormone, suggesting that host inflammatory responses induced by FGF-2 are associated with FGF-2-induced tumor progression. In addition, although FGF-2 did not promote cellular proliferation and vascular endothelial growth factor A (VEGFA) mRNA expression in B16-BL6 cells in vitro, FGF-2 induced VEGFA expression in host stroma rather than tumor tissue, and local injections of a neutralizing antibody against VEGFA inhibited these activities of FGF-2 in vivo. These results indicate that abundant FGF-2 during the initial phase of tumor growth induces VEGFA-dependent intensive neovascularization in host stroma, and supports marked tumor growth and metastasis.

GPHS-RTGs in support of the Cassini Mission. Semi annual technical progress report, 1 April 1996--29 September 1996

International Nuclear Information System (INIS)

1996-01-01

This technical progress report discusses work on the Radioisotope Generators and Ancillary Activities for the Cassini spacecraft. The Cassini spacecraft is expected to launch in October 1997, and will explore Saturn and its moons. This progress report discusses issues in: spacecraft integration and liason, engineering support, safety, qualified unicouple fabrication, ETG fabrication and testing, ground support equipment, RTG shipping and launch support, designs, reviews and mission application. Safety analysis of the RTGs during reentry and launch accidents are covered. This report covers the period of April 1 to September 29, 1996

Technical reliability of geological disposal for high-level radioactive wastes in Japan. The second progress report. Part 1. Geological environment of Japan

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-11-01

Based on the Advisory Committee Report on Nuclear Fuel Cycle Backend Policy submitted to the Japanese Government in 1997, JNC documents the progress of research and development program in the form of the second progress report (the first one published in 1992). It summarizes an evaluation of the technical reliability and safety of the geological disposal concept for high-level radioactive wastes (HLW) in Japan. The present document, the part 1 of the progress report, describes first in detail the role of geological environment in high-level radioactive wastes disposal, the features of Japanese geological environment, and programs to proceed the investigation in geological environment. The following chapter summarizes scientific basis for possible existence of stable geological environment, stable for a long period needed for the HLW disposal in Japan including such natural phenomena as volcano and faults. The results of the investigation of the characteristics of bed-rocks and groundwater are presented. These are important for multiple barrier system construction of deep geological disposal. The report furthermore describes the present status of technical and methodological progress in investigating geological environment and finally on the results of natural analog study in Tono uranium deposits area. (Ohno, S.)

Multistep change in epidermal growth factor receptors during spontaneous neoplastic progression in Chinese hamster embryo fibroblasts

International Nuclear Information System (INIS)

Wakshull, E.; Kraemer, P.M.; Wharton, W.

1985-01-01

Whole Chinese hamster embryo lineages have been shown to undergo multistep spontaneous neoplastic progression during serial passage in culture. The authors have studied the binding, internalization, and degradation of 125 I-labeled epidermal growth factor at four different stages of transformation. The whole Chinese hamster embryo cells lost cell surface epidermal growth factor receptors gradually during the course of neoplastic progression until only 10% of the receptor number present in the early-passage cells (precrisis) were retained in the late-passage cells (tumorigenic). No differences in internalization rates, chloroquine sensitivity, or ability to degrade hormone between the various passage levels were seen. No evidence for the presence in conditioned medium of transforming growth factors which might mask or down-regulate epidermal growth factor receptor was obtained. These results suggest that a reduction in cell surface epidermal growth factor receptor might be an early event during spontaneous transformation in whole Chinese hamster embryo cells

High-Efficiency Nitride-Based Solid-State Lighting. Final Technical Progress Report

International Nuclear Information System (INIS)

Paul T. Fini; Shuji Nakamura

2005-01-01

In this final technical progress report we summarize research accomplished during Department of Energy contract DE-FC26-01NT41203, entitled ''High-Efficiency Nitride-Based Solid-State Lighting''. Two teams, from the University of California at Santa Barbara (Principle Investigator: Dr. Shuji Nakamura) and the Lighting Research Center at Rensselaer Polytechnic Institute (led by Dr. N. Narendran), pursued the goals of this contract from thin film growth, characterization, and packaging/luminaire design standpoints. The UCSB team initially pursued the development of blue gallium nitride (GaN)-based vertical-cavity surface-emitting lasers, as well as ultraviolet GaN-based light emitting diodes (LEDs). In Year 2, the emphasis shifted to resonant-cavity light emitting diodes, also known as micro-cavity LEDs when extremely thin device cavities are fabricated. These devices have very directional emission and higher light extraction efficiency than conventional LEDs. Via the optimization of thin-film growth and refinement of device processing, we decreased the total cavity thickness to less than 1 (micro)m, such that micro-cavity effects were clearly observed and a light extraction efficiency of over 10% was reached. We also began the development of photonic crystals for increased light extraction, in particular for so-called ''guided modes'' which would otherwise propagate laterally in the device and be re-absorbed. Finally, we pursued the growth of smooth, high-quality nonpolar a-plane and m-plane GaN films, as well as blue light emitting diodes on these novel films. Initial nonpolar LEDs showed the expected behavior of negligible peak wavelength shift with increasing drive current. M-plane LEDs in particular show promise, as unpackaged devices had unsaturated optical output power of ∼ 3 mW at 200 mA drive current. The LRC's tasks were aimed at developing the subcomponents necessary for packaging UCSB's light emitting diodes, and packaging them to produce a white light

Index to Nuclear Safety: a technical progress review by chronology, permuted title, and author. Vol. 11(1)--Vol. 18(6)

Energy Technology Data Exchange (ETDEWEB)

Cottrell, W.B.; Klein, A.

1978-04-11

This index to Nuclear Safety covers articles published in Nuclear Safety, Vol. 11, No. 1 (January-February 1970), through Vol. 18, No. 6 (November-December 1977). It is divided into three sections: a chronological list of articles (including abstracts) followed by a permuted-title (KWIC) index and an author index. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center (NSIC), covers all safety aspects of nuclear power reactors and associated facilities. Over 450 technical articles published in Nuclear Safety in the last eight years are listed in this index.

Index to Nuclear Safety: a technical progress review by chronology, permuted title, and author. Vol. 11(1)--Vol. 18(6)

International Nuclear Information System (INIS)

Cottrell, W.B.; Klein, A.

1978-01-01

This index to Nuclear Safety covers articles published in Nuclear Safety, Vol. 11, No. 1 (January-February 1970), through Vol. 18, No. 6 (November-December 1977). It is divided into three sections: a chronological list of articles (including abstracts) followed by a permuted-title (KWIC) index and an author index. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center (NSIC), covers all safety aspects of nuclear power reactors and associated facilities. Over 450 technical articles published in Nuclear Safety in the last eight years are listed in this index

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 1. Technical Report # 0919

Science.gov (United States)

Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grade 1. These measures, available as part of easyCBM [TM], an online progress monitoring assessment system, were developed in 2008 and administered to approximately 2800 students from schools…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 2. Technical Report # 0920

Science.gov (United States)

Alonzo, Julie; Lai, Cheng Fei; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 7. Technical Report 0908

Science.gov (United States)

Lai, Cheng Fei; Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

Technical reliability of geological disposal for high-level radioactive wastes in Japan. The second progress report. Introductory part and summaries

International Nuclear Information System (INIS)

1999-11-01

Based on the Advisory Committee Report on Nuclear Fuel Cycle Backend Policy submitted to the Japanese Government in 1997, JNC documents the progress of research and development program in the form of the second progress report (the first one published in 1992). It summarizes an evaluation of the technical reliability and safety of the geological disposal concept for high-level radioactive wastes (HLW) in Japan and comprises seven chapters. Chapter I briefly describes the importance of HLW management in promoting nuclear energy utilization. According to the long-term program, the HLW separated from spent fuels at reprocessing plants is to be vitrified and stored for a period of 30 to 50 years to allow cooling, then be disposed of in a deep geological formation. Chapter II mainly explains the concepts of geological disposal in Japan. Chapters III to V are devoted to discussions on three important technical elements (the geological environment of Japan, engineering technology and safety assessment of the geological disposal system) which are necessary for reliable realization of the geological disposal concept. Chapter VI demonstrates the technical ground for site selection and for setup of safety standards of the disposal. Chapter VII summarizes together with plans for future research and development. (Ohno, S.)

Progresso tecnico, forme di mercato e disoccupazione. ( Technical progress, market forms and unemployment

Directory of Open Access Journals (Sweden)

A. ASIMAKOPULOS A.

2013-12-01

Full Text Available Lo scopo del presente lavoro è triplice . Il primo obiettivo è quello di sottolineare l'importanza delle intuizioni da trovare nel lavoro di Sylos Labini . Il secondo scopo è quello di espandere su di essa distinguendo tra i diversi tipi di progresso tecnico . Infine , il terzo obiettivo è quello di commentare il confronto di Labini di Ricardo e Keynes sulla possibilità di disoccupazione tecnologica . Per quanto riguarda la sua descrizione del progresso tecnologico come " risparmio di lavoro " , l'autore mostra che una descrizione più completa sarebbe più utile per i suoi scopiThe purpose of the present paper is threefold. The first purpose is to emphasise the importance of the insights to be found in Sylos Labini’s work. The second purpose is to expand upon it by distinguishing  between the different types of technical progress. Finally, the third purpose is to comment on Labini’s comparison of Ricardo and Keynes on the possibility of technological unemployment. Regarding his description of technological progress as “labour saving”, the author shows that a more comprehensive description would be more useful for his purposes.JEL: E24, J64, O33

Technical progress and efficiency changes in football teams participating in the UEFA Champions League

Directory of Open Access Journals (Sweden)

Lucía Isabel García Cebrián

2015-09-01

Full Text Available This paper commits to calculate and analyze productivy levels and its components for teams that participated in the UEFA Champions League between 2003 and 2012. It will pursue three objectives: 1 evaluate resources usage, 2 analyze the productivity levels of the football teams and the sports results, and 3 see the influence of participation experience in reference to productivity and sports results. Using Malmquist Productivity Index, the results reflect a lack of consistent progression of efficiency, productivity, and technical change. This competition does not reward the efficient usage of resources and there is not a conclusive relationshop between permanence in the competition and productivity.

Volatiles combustion in fluidized beds. Technical progress report, 4 March 1993--3 June 1993

Energy Technology Data Exchange (ETDEWEB)

Hesketh, R.P.

1993-09-01

The goal of this project is to investigate the conditions in which volatiles will burn within both the dense and freeboard regions of fluidized beds. Experiments using a fluidized bed operated at incipient fluidization will be performed to characterize the effect of particle surface area, initial fuel concentration, and particle type on the inhibition of volatiles within a fluidized bed. The work conducted during the period 4 March, 1993 through 3 June, 1993 is reported in this technical progress report. The work during this time period consists primarily of the startup and trouble shooting of the fluidized bed reactor and gas phase modeling of methane and propane.

Economic growth and decline in mortality in developing countries: an analysis of the World Bank development datasets.

Science.gov (United States)

Renton, A; Wall, M; Lintott, J

2012-07-01

The 1999 World Bank report claimed that growth in gross domestic product (GDP) between 1960 and 1990 only accounted for 15% of concomitant growth in life expectancy in developing countries. These findings were used repeatedly by the World Health Organization (WHO) to support a policy shift away from promoting social and economic development, towards vertical technology-driven programmes. This paper updates the 1999 World Bank report using the World Bank's 2005 dataset, providing a new assessment of the relative contribution of economic growth. Time-series analysis. Cross-sectional time-series regression analysis using a random effect model of associations between GDP, education and technical progress and improved health outcomes. The proportion of improvement in health indicators between 1970 and 2000 associated with changes in GDP, education and technical progress was estimated. In 1970, a 1% difference in GDP between countries was associated with 6% difference in female (LEBF) and 5% male (LEBM) life expectancy at birth. By 2000, these values had increased to 14% and 12%, explaining most of the observed health gain. Excluding Europe and Central Asia, the proportion of the increase in LEBF and LEBM attributable to increased GDP was 31% and 33% in the present analysis, vs. 17% and 14%, respectively, estimated by the World Bank. In the poorest countries, higher GDPs were required in 2000 than in 1970 to achieve the same health outcomes. In the poorest countries, socio-economic change is likely to be a more important source of health improvement than technical progress. Technical progress, operating by increasing the size of the effect of a unit of GDP on health, is likely to benefit richer countries more than poorer countries, thereby increasing global health inequalities. Copyright © 2012 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

Guidance for growth factors, projections, and control strategies for the 15 percent rate-of-progress plans

International Nuclear Information System (INIS)

1993-03-01

Section 182(b)(1) of the Clean Air Act (Act) requires all ozone nonattainment areas classified as moderate and above to submit a State Implementation Plan (SIP) revision by November 15, 1993, which describes, in part, how the areas will achieve an actual volatile organic compound (VOC) emissions reduction of at least 15 percent during the first 6 years after enactment of the Clean Air Act Amendments of 1990 (CAAA). In addition, the SIP revision must describe how any growth in emissions from 1990 through 1996 will be fully offset. It is important to note that section 182(b)(1) also requires the SIP for moderate areas to provide for reductions in VOC and nitrogen oxides (NOx) emissions as necessary to attain the national primary ambient air quality standard for ozone by November 15, 1996. The guidance document focuses on the procedures for developing 1996 projected emissions inventories and control measures which moderate and above ozone nonattainment areas must include in their rate-of-progress plans. The document provides technical guidance to support the policy presented in the 'General Preamble: Implementation of Title I of the CAAA of 1990' (57 FR 13498)

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 3. Technical Report # 09-02

Science.gov (United States)

Alonzo, Julie; Lai, Cheng Fei; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 5. Technical Report # 09-01

Science.gov (United States)

Lai, Cheng Fei; Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 4. Technical Report # 09-03

Science.gov (United States)

Alonzo, Julie; Lai, Cheng Fei; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

The Development of K-8 Progress Monitoring Measures in Mathematics for Use with the 2% and General Education Populations: Grade 8. Technical Report # 09-04

Science.gov (United States)

Lai, Cheng Fei; Alonzo, Julie; Tindal, Gerald

2009-01-01

In this technical report, we describe the development and piloting of a series of mathematics progress monitoring measures intended for use with students in grades kindergarten through eighth grade. These measures, available as part of easyCBM[TM], an online progress monitoring assessment system, were developed in 2007 and 2008 and administered to…

National Council on Radiation Protection and Measurements semiannual technical progress report, March 1989--August 1989

International Nuclear Information System (INIS)

Ney, W.R.

1991-01-01

This semiannual technical progress report is for the period 1 March 1989 through 31 August 1989. This National Council on Radiation Protection and Measurements (NCRP) program is designed to provide recommendations for radiation protection based on scientific principles. During this period several reports were published covering the topics of occupational radiation exposure, medical exposure, radon control, dosimetry, and radiation protection standards. Accomplishments of various committees are also reported; including the committees on dental x-ray protection, radiation safety in uranium mining and milling, ALARA, instrumentation, records maintenance, occupational exposures of medical personnel, emergency planning, and others. (SM)

Index to Nuclear Safety: a technical progress review by chronology, permuted title, and author, Volume 18 (1) through Volume 22 (6)

International Nuclear Information System (INIS)

Cottrell, W.B.; Passiakos, M.

1982-06-01

This index to Nuclear Safety covers articles published in Nuclear Safety, Volume 18, Number 1 (January-February 1977) through Volume 22, Number 6 (November-December 1981). The index is divided into three section: a chronological list of articles (including abstracts), a permuted-title (KWIC) index, and an author index. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center, covers all safety aspects of nuclear power reactors and associated facilities. Over 300 technical articles published in Nuclear Safety in the last 5 years are listed in this index

Index to Nuclear Safety: a technical progress review by chronology, permuted title, and author, Volume 18 (1) through Volume 22 (6)

Energy Technology Data Exchange (ETDEWEB)

Cottrell, W.B.; Passiakos, M.

1982-06-01

This index to Nuclear Safety covers articles published in Nuclear Safety, Volume 18, Number 1 (January-February 1977) through Volume 22, Number 6 (November-December 1981). The index is divided into three section: a chronological list of articles (including abstracts), a permuted-title (KWIC) index, and an author index. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center, covers all safety aspects of nuclear power reactors and associated facilities. Over 300 technical articles published in Nuclear Safety in the last 5 years are listed in this index.

Index to Nuclear Safety. A technical progress review by chronology, permuted title, and author. Vol. 11, No. 1--Vol. 17, No. 6

International Nuclear Information System (INIS)

Cottrell, W.B.; Klein, A.

1977-01-01

This index to Nuclear Safety covers articles in Nuclear Safety Vol. 11, No. 1 (Jan.-Feb. 1970), through Vol. 17, No. 6 (Nov.-Dec. 1976). The index includes a chronological list of articles (including abstract) followed by KWIC and Author Indexes. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center, covers all safety aspects of nuclear power reactors and associated facilities. The index lists over 350 technical articles in the last six years of publication

Index to Nuclear Safety. A technical progress review by chronology, permuted title, and author. Vol. 11, No. 1--Vol. 17, No. 6

Energy Technology Data Exchange (ETDEWEB)

Cottrell, W.B.; Klein, A.

1977-02-23

This index to Nuclear Safety covers articles in Nuclear Safety Vol. 11, No. 1 (Jan.-Feb. 1970), through Vol. 17, No. 6 (Nov.-Dec. 1976). The index includes a chronological list of articles (including abstract) followed by KWIC and Author Indexes. Nuclear Safety, a bimonthly technical progress review prepared by the Nuclear Safety Information Center, covers all safety aspects of nuclear power reactors and associated facilities. The index lists over 350 technical articles in the last six years of publication.

Evaluation of geothermal energy in Arizona. Arizona geothermal planning/commercialization team. Quarterly topical progress report, July 1-September 30, 1980

Energy Technology Data Exchange (ETDEWEB)

White, D.H.; Mancini, F.; Goldstone, L.A.; Malysa, L.

1980-01-01

Progress is reviewed on the following: area development plans, evaluation of geothermal applications, continued evaluation of geothermal resources, engineering and economic analyses, technical assistance in the state of Arizona, the impact of various growth patterns upon geothermal energy development, and the outreach program. (MHR)

Technical innovation and management

Energy Technology Data Exchange (ETDEWEB)

Yoon, Yang Cheol

1982-08-15

This book gives explanations of the conception of technical innovation, development plan in Korea, connection between technology and a growth factor in national income, problem of technical innovation in developing country, analysis on cooperation between a developed country and a developing country, evaluation and strategy of technical development in Korea, technical innovation of industry, management of technical industry, analysis of special condition in Korea.

Technical innovation and management

International Nuclear Information System (INIS)

Yoon, Yang Cheol

1982-08-01

This book gives explanations of the conception of technical innovation, development plan in Korea, connection between technology and a growth factor in national income, problem of technical innovation in developing country, analysis on cooperation between a developed country and a developing country, evaluation and strategy of technical development in Korea, technical innovation of industry, management of technical industry, analysis of special condition in Korea.

Biomedical Progress Rates as New Parameters for Models of Economic Growth in Developed Countries

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Alex Zhavoronkov

2013-11-01

Full Text Available While the doubling of life expectancy in developed countries during the 20th century can be attributed mostly to decreases in child mortality, the trillions of dollars spent on biomedical research by governments, foundations and corporations over the past sixty years are also yielding longevity dividends in both working and retired population. Biomedical progress will likely increase the healthy productive lifespan and the number of years of government support in the old age. In this paper we introduce several new parameters that can be applied to established models of economic growth: the biomedical progress rate, the rate of clinical adoption and the rate of change in retirement age. The biomedical progress rate is comprised of the rejuvenation rate (extending the productive lifespan and the non-rejuvenating rate (extending the lifespan beyond the age at which the net contribution to the economy becomes negative. While staying within the neoclassical economics framework and extending the overlapping generations (OLG growth model and assumptions from the life cycle theory of saving behavior, we provide an example of the relations between these new parameters in the context of demographics, labor, households and the firm.

Biomedical progress rates as new parameters for models of economic growth in developed countries.

Science.gov (United States)

Zhavoronkov, Alex; Litovchenko, Maria

2013-11-08

While the doubling of life expectancy in developed countries during the 20th century can be attributed mostly to decreases in child mortality, the trillions of dollars spent on biomedical research by governments, foundations and corporations over the past sixty years are also yielding longevity dividends in both working and retired population. Biomedical progress will likely increase the healthy productive lifespan and the number of years of government support in the old age. In this paper we introduce several new parameters that can be applied to established models of economic growth: the biomedical progress rate, the rate of clinical adoption and the rate of change in retirement age. The biomedical progress rate is comprised of the rejuvenation rate (extending the productive lifespan) and the non-rejuvenating rate (extending the lifespan beyond the age at which the net contribution to the economy becomes negative). While staying within the neoclassical economics framework and extending the overlapping generations (OLG) growth model and assumptions from the life cycle theory of saving behavior, we provide an example of the relations between these new parameters in the context of demographics, labor, households and the firm.

Progress report : Technical Physics Division

International Nuclear Information System (INIS)

Gopalaraman, C.P.; Deshpande, R.Y.

1978-01-01

The research and development work carried out in the Technical Physics Division of the Bhabha Atomic Research Centre, Bombay, is reported. Some of the achievements are: (1) fabrication of mass spectrometers for heavy water analysis and lithium 6/7 isotope ratio measurement, (2) fabrication of electronic components for mass spectrometers, (3) growing of sodium iodide crystals for radiation detectors, (4) development of sandwich detectors comprising of NaI(Tl) and CaI(Na), (5) fabrication of mass spectrometer type leak detectors and (6) fabrication of the high vacuum components of the vacuum system of the variable energy cyclotron based at Calcutta. (M.G.B.)

ERECTA-family receptor kinase genes redundantly prevent premature progression of secondary growth in the Arabidopsis hypocotyl.

Science.gov (United States)

Ikematsu, Shuka; Tasaka, Masao; Torii, Keiko U; Uchida, Naoyuki

2017-03-01

Secondary growth is driven by continuous cell proliferation and differentiation of the cambium that acts as vascular stem cells, producing xylem and phloem to expand vascular tissues laterally. During secondary growth of hypocotyls in Arabidopsis thaliana, the xylem undergoes a drastic phase transition from a parenchyma-producing phase to a fiber-producing phase at the appropriate time. However, it remains to be fully elucidated how progression of secondary growth is properly controlled. We focused on phenotypes of hypocotyl vasculatures caused by double mutation in ERECTA (ER) and ER-LIKE1 (ERL1) receptor-kinase genes to elucidate their roles in secondary growth. ER and ERL1 redundantly suppressed excessive radial growth of the hypocotyl vasculature during secondary growth. ER and ERL1 also prevented premature initiation of the fiber differentiation process mediated by the NAC SECONDARY WALL THICKENING PROMOTING FACTORs in the hypocotyl xylem. Upon floral transition, the hypocotyl xylem gained a competency to respond to GA in a BREVIPEDICELLUS-dependent manner, which was a prerequisite for fiber differentiation. However, even after the floral transition, ER and ERL1 prevented precocious initiation of the GA-mediated fiber formation. Collectively, our findings reveal that ER and ERL1 redundantly prevent premature progression of sequential events in secondary growth. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.

Connective tissue growth factor immunohistochemical expression is associated with gallbladder cancer progression.

Science.gov (United States)

Garcia, Patricia; Leal, Pamela; Alvarez, Hector; Brebi, Priscilla; Ili, Carmen; Tapia, Oscar; Roa, Juan C

2013-02-01

Gallbladder cancer (GBC) is an aggressive neoplasia associated with late diagnosis, unsatisfactory treatment, and poor prognosis. Molecular mechanisms involved in GBC pathogenesis remain poorly understood. Connective tissue growth factor (CTGF) is thought to play a role in the pathologic processes and is overexpressed in several human cancers, including GBC. No information is available about CTGF expression in early stages of gallbladder carcinogenesis. Objective.- To evaluate the expression level of CTGF in benign and malignant lesions of gallbladder and its correlation with clinicopathologic features and GBC prognosis. Connective tissue growth factor protein was examined by immunohistochemistry on tissue microarrays containing tissue samples of chronic cholecystitis (n = 51), dysplasia (n = 15), and GBC (n = 169). The samples were scored according to intensity of staining as low/absent and high CTGF expressers. Statistical analysis was performed using the χ(2) test or Fisher exact probability test with a significance level of P Connective tissue growth factor expression showed a progressive increase from chronic cholecystitis to dysplasia and then to early and advanced carcinoma. Immunohistochemical expression (score ≥2) was significantly higher in advanced tumors, in comparison with chronic cholecystitis (P < .001) and dysplasia (P = .03). High levels of CTGF expression correlated with better survival (P = .04). Our results suggest a role for CTGF in GBC progression and a positive association with better prognosis. In addition, they underscore the importance of considering the involvement of inflammation on GBC development.

AN ANALYSIS OF HUMAN CAPITAL DEVELOPMENT AND PRODUCTIVITY GROWTH- CASE STUDY, NIGERIA

Directory of Open Access Journals (Sweden)

Opeyemi Oluwabunmi Adejumo

2017-09-01

Full Text Available In order to address the direction of causality between human capital and productivity growth in Nigeria, the study first investigated the pattern of productivity growth in Nigeria between 1970 and 2010. Following the endogenous growth model, which argued that technical progress, through an effective labor force, could lead to long-run growth which can be determined from within an economy; but it actually depends on the efficiency with which resources available to such an economy are utilized. This is against the exogenous growth model which emphasized that long-run growth can be attained by some unexplained technological progress, which is exogenous to any economy. Based on this controversy in literature, this study empirically determined the productivity growth in Nigeria, as well as the causal relation between human capital development and productivity growth in Nigeria using the Engle-Granger causality test. The results revealed that productivity growth has been very low and unstable in Nigeria as it oscillated between -1.5% and 0.6%. In addition, the nexus between human capital and productivity growth was examined. The findings revealed that while productivity growth caused human capital development, human capital development did not cause productivity growth.

Solar lease grant program. Technical progress report

Energy Technology Data Exchange (ETDEWEB)

1981-04-01

Progress on a lease program for the installation of a solar water heater with no installation charge is reported. Information on the announcement of the program, the selection of participants, the contractural agreement, progress on installation of equipment, monitoring, and evaluation is summarized. The status of the budget concerned with the program is announced. Forms used for applications for the program and an announcement from Resource Alternatives for Cilco customers are presented.

Economic growth and health progress in England and Wales: 160 years of a changing relation.

Science.gov (United States)

Tapia Granados, José A

2012-03-01

Using data for England and Wales during the years 1840-2000, a negative relation is found between economic growth--measured by the rate of growth of gross domestic product (GDP)--and health progress--as indexed by the annual increase in life expectancy at birth (LEB). That is, the lower is the rate of growth of the economy, the greater is the annual increase in LEB for both males and females. This effect is much stronger, however, in 1900-1950 than in 1950-2000, and is very weak in the 19th century. It appears basically at lag zero, though some short-lag effects of the same negative sign are found. In the other direction of causality, there are very small effects of the change in LEB on economic growth. These results add to an emerging consensus that in the context of long-term declining trends, mortality oscillates procyclically during the business cycle, declining faster in recessions. Therefore, LEB increases faster during recessions than during expansions. The investigation also shows how the relation between economic growth and health progress changed in England and Wales during the study period. No evidence of cointegration between income--as indexed by GDP or GDP per capita--and health--as indexed by LEB--is found. Copyright © 2012 Elsevier Ltd. All rights reserved.

Technical progress report

International Nuclear Information System (INIS)

1996-01-01

This report summarizes experimental and theoretical work in basic nuclear physics carried out between October 1, 1995, the closing of our last Progress Report, and September 30, 1996 at the Nuclear Physics Laboratory of the University of Colorado, Boulder, under contracts DE-FG03-93ER-40774 and DE-FG03-95ER-40913 with the United States Department of Energy. The experimental contract supports broadly-based experimental research in intermediate energy nuclear physics. This report includes results from studies of Elementary Systems involving the study of the structure of the nucleon via polarized high-energy positron scattering (the HERMES experiment) and lower energy pion scattering from both polarized and unpolarized nucleon targets. Results from pion- and kaon-induced reactions in a variety of nuclear systems are reported under the section heading Meson Reactions; the impact of these and other results on understanding the nucleus is presented in the Nuclear Structure section. In addition, new results from scattering of high-energy electrons (from CEBAF/TJNAF) and pions (from KEK) from a broad range of nuclei are reported in the section on Incoherent Reactions. Finally, the development and performance of detectors produced by the laboratory are described in the section titled Instrumentation

Basic fibroblast growth factor in an animal model of spontaneous mammary tumor progression.

Science.gov (United States)

Kao, Steven; Mo, Jeffrey; Baird, Andrew; Eliceiri, Brian P

2012-06-01

Although basic fibroblast growth factor (FGF2) was the first pro-angiogenic molecule discovered, it has numerous activities on the growth and differentiation of non-vascular cell types. FGF2 is both stimulatory and inhibitory, depending on the cell type evaluated, the experimental design used and the context in which it is tested. Here, we investigated the effects of manipulating endogenous FGF2 on the development of mammary cancer to determine whether its endogenous contribution in vivo is pro- or anti-tumorigenic. Specifically, we examined the effects of FGF2 gene dosing in a cross between a spontaneous breast tumor model (PyVT+ mice) and FGF2-/- (FGF KO) mice. Using these mice, the onset and progression of mammary tumors was determined. As predicted, female FGF2 WT mice developed mammary tumors starting around 60 days after birth and by 80 days, 100% of FGF2 WT female mice had mammary tumors. In contrast, 80% of FGF2 KO female mice had no palpable tumors until nearly three weeks later (85 days) at times when 100% of the WT cohort was tumor positive. All FGF KO mice were tumor-bearing by 115 days. When we compared the onset of mammary tumor development and the tumor progression curves between FGF het and FGF KO mice, we observed a difference, which suggested a gene dosing effect. Analysis of the tumors demonstrated that there were significant differences in tumor size depending on FGF2 status. The delay in tumor onset supports a functional role for FGF2 in mammary tumor progression, but argues against an essential role for FGF2 in overall mammary tumor progression.

A systematic assessment of the state of hazardous waste clean-up technologies. Quarterly technical progress report, April 1--June 30, 1993

Energy Technology Data Exchange (ETDEWEB)

Berg, M.T.; Reed, B.E.; Gabr, M.

1993-07-01

West Virginia University (WVU) and the US DOE Morgantown Energy Technology Center (METC) entered into a Cooperative Agreement on August 29, 1992 entitled ``Decontamination Systems Information and Research Programs.`` Stipulated within the Agreement is the requirement that WVU submit to METC a series of Technical Progress Report for Year 1 of the Agreement. This report reflects the progress and/or efforts performed on the following nine technical projects encompassed by the Year 1 Agreement for the period of April 1 through June 30, 1993: Systematic assessment of the state of hazardous waste clean-up technologies; site remediation technologies -- drain-enhanced soil flushing (DESF) for organic contaminants removal; site remediation technologies -- in situ bioremediation of organic contaminants; excavation systems for hazardous waste sites; chemical destruction of polychlorinated biphenyls; development of organic sensors -- monolayer and multilayer self-assembled films for chemical sensors; Winfield lock and dam remediation; Assessments of Technologies for hazardous waste site remediation -- non-treatment technologies and pilot scale test facility implementation; and remediation of hazardous sites with stream reforming.

Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression.

Directory of Open Access Journals (Sweden)

Nitin Patel

Full Text Available Prostate cancer (PCa is the second-leading cause of cancer-related mortality, after lung cancer, in men from developed countries. In its early stages, primary tumor growth is dependent on androgens, thus generally can be controlled by androgen deprivation therapy (ADT. Eventually however, the disease progresses to castration-resistant prostate cancer (CRPC, a lethal form in need of more effective treatments. G-protein coupled receptors (GPCRs comprise a large clan of cell surface proteins that have been implicated as therapeutic targets in PCa growth and progression. The findings reported here provide intriguing evidence of a role for the newly characterized glutamate family member GPR158 in PCa growth and progression. We found that GPR158 promotes PCa cell proliferation independent of androgen receptor (AR functionality and that this requires its localization in the nucleus of the cell. This suggests that GPR158 acts by mechanisms different from other GPCRs. GPR158 expression is stimulated by androgens and GPR158 stimulates AR expression, implying a potential to sensitize tumors to low androgen conditions during ADT via a positive feedback loop. Further, we found GPR158 expression correlates with a neuroendocrine (NE differentiation phenotype and promotes anchorage-independent colony formation implying a role for GPR158 in therapeutic progression and tumor formation. GPR158 expression was increased at the invading front of prostate tumors that formed in the genetically defined conditional Pten knockout mouse model, and co-localized with elevated AR expression in the cell nucleus. Kaplan-Meier analysis on a dataset from the Memorial Sloan Kettering cancer genome portal showed that increased GPR158 expression in tumors is associated with lower disease-free survival. Our findings strongly suggest that pharmaceuticals targeting GPR158 activities could represent a novel and innovative approach to the prevention and management of CRPC.

GT-MHR COMMERCIALZATION STUDY. TECHNICAL PROGRESS AND COST MANAGEMENT REPORT FOR THE PERIOD MAY 1 THROUGH MAY 31, 2003

International Nuclear Information System (INIS)

SHENOY, A.S.

2003-01-01

A271 GT-MHR COMMERCIALZATION STUDY TECHNICAL PROGRESS AND COST MANAGEMENT REPORT FOR THE PERIOD MAY 1 THROUGH MAY 31, 2003. Petten advised GA the start of the HFR-EU2 irradiation is being delayed until late July 2004. HFR-EU1 (pebble fuel) is also delayed until February/March 2004. The reason for the delays was implementation of new financial regulations at Petten that delayed the contracts for capsule fabrication. Review of the MHR-2 Fuel Product Specification was completed. Revision of the specification to incorporate the review results is in progress. Detailed test matrices have been drafted for capsule irradiation tests and for post-irradiation heating tests proposed for development and qualification of advanced coated-particle fuels capable of meeting anticipated VHTR fuel performance requirements

Index to Nuclear Safety. A technical progress review by chronology, permuted title, and author. Vol 11, No. 1 through Vol. 16, No. 6

International Nuclear Information System (INIS)

Cottrell, W.B.; Klein, A.

1976-04-01

This index to Nuclear Safety covers articles in Nuclear Safety Vol. 11, No. 1 (Jan.-Feb. 1970) through Vol. 16, No. 6 (Nov.-Dec. 1975). Included in the index is a chronological list of articles (including abstract) followed by both a KWIC index and an Author Index. Nuclear Safety is a bimonthly technical progress review prepared by the Nuclear Safety Information Center and covers all safety aspects of nuclear power reactors and associated facilities. The index lists over 300 technical articles in the last six years of publication

Index to Nuclear Safety. A technical progress review by chronology, permuted title, and author. Vol 11, No. 1 through Vol. 16, No. 6

Energy Technology Data Exchange (ETDEWEB)

Cottrell, W.B.; Klein, A.

1976-04-01

This index to Nuclear Safety covers articles in Nuclear Safety Vol. 11, No. 1 (Jan.-Feb. 1970) through Vol. 16, No. 6 (Nov.-Dec. 1975). Included in the index is a chronological list of articles (including abstract) followed by both a KWIC index and an Author Index. Nuclear Safety is a bimonthly technical progress review prepared by the Nuclear Safety Information Center and covers all safety aspects of nuclear power reactors and associated facilities. The index lists over 300 technical articles in the last six years of publication.

Urology technical and non-technical skills development: the emerging role of simulation.

Science.gov (United States)

Rashid, Prem; Gianduzzo, Troy R J

2016-04-01

To review the emerging role of technical and non-technical simulation in urological education and training. A review was conducted to examine the current role of simulation in urology training. A PUBMED search of the terms 'urology training', 'urology simulation' and 'urology education' revealed 11,504 titles. Three hundred and fifty-seven abstracts were identified as English language, peer reviewed papers pertaining to the role of simulation in urology and related topics. Key papers were used to explore themes. Some cross-referenced papers were also included. There is an ongoing need to ensure that training time is efficiently utilised while ensuring that optimal technical and non-technical skills are achieved. Changing working conditions and the need to minimise patient harm by inadvertent errors must be taken into account. Simulation models for specific technical aspects have been the mainstay of graduated step-wise low and high fidelity training. Whole scenario environments as well as non-technical aspects can be slowly incorporated into the curriculum. Doing so should also help define what have been challenging competencies to teach and evaluate. Dedicated time, resources and trainer up-skilling are important. Concurrent studies are needed to help evaluate the effectiveness of introducing step-wise simulation for technical and non-technical competencies. Simulation based learning remains the best avenue of progressing surgical education. Technical and non-technical simulation could be used in the selection process. There are good economic, logistic and safety reasons to pursue the process of ongoing development of simulation co-curricula. While the role of simulation is assured, its progress will depend on a structured program that takes advantage of what can be delivered via this medium. Overall, simulation can be developed further for urological training programs to encompass technical and non-technical skill development at all stages, including

Power systems development facility. Quarterly technical progress report, January 1, 1994--March 31, 1994

Energy Technology Data Exchange (ETDEWEB)

1994-07-01

This quarterly technical progress report summarizes work completed during the last quarter of the Second Budget Period, January 1 through March 31, 1994, entitled {open_quotes}Hot Gas Cleanup Test Facility for Gasification and Pressurized Combustion.{close_quotes} The objective of this project is to evaluate hot gas particulate control technologies using coal-derived gas streams. This will entail the design, construction, installation, and use of a flexible test facility which can operate under realistic gasification and combustion conditions. The major particulate control device issues to be addressed include the integration of the particulate control devices into coal utilization systems, on-line cleaning techniques, chemical and thermal degradation of components, fatigue or structural failures, blinding, collection efficiency as a function of particle size, and scale-up of particulate control systems to commercial size.

48 CFR 742.1170-4 - Progress reporting requirements and contract clause.

Science.gov (United States)

2010-10-01

... progress. (b) Because the cognizant technical officer is the individual most familiar with the contractor's performance, the contractor must submit the progress reports directly to the cognizant technical officer. The cognizant technical officer must review the reports and advise the contracting officer, in writing, of any...

Technical and Vocational Education and Training for Economic Growth in Pakistan

Directory of Open Access Journals (Sweden)

Shirin Nooruddin

2017-06-01

Full Text Available This discussion paper aims to highlight the existing scenario of Technical and Vocational Education and Training (TVET for the economic growth in Pakistan. It specifically analysis the status of vocational training, related policies and practices with reference to the 18th Amendment, which abolishes the concurrent list and grants more provincial autonomy in the matters of education. Article 25A of the Constitution of the Islamic Republic of Pakistan (iv states that the provinces should set priorities for access and quality education based on the provincial needs and develop action plans for its actualization. A developing country like Pakistan needs to devise a systematic, well thought and sophisticated policy for TVET; therefore, this paper proposes a policy following the simple framework of input, process and output. The inputs are predominantly focused on highlighting and matching demand and supply of the TVET. The process thoroughly discusses both the formal and informal education arrangements. Finally, the outputs are deliberated in the form of economic effects such as the manpower structures, technological development, manpower quality and economic behavior leading to the ultimate goal of economic growth and development of the country.

Does gross capital formation matter for economic growth in the CEMAC sub-region?

Directory of Open Access Journals (Sweden)

Emmanuel Nkoa Ongo

2014-11-01

Full Text Available This paper examines the effect of gross capital formation on the economic growth of the CEMAC sub- region. It draws inspiration from the endogenous growth model. Data for the study is collected from the World Bank Development Indicators. The estimation technique used for this study is the Generalized Least Square estimation technique. The results show that private investment has a significant positive association with economic growth. This is also the case of technical progress and infrastructural development. On the contrary, labour force tends to affect negatively economic growth in this sub-region. This suggests that countries of the sub region need to implement realistic employment policies.

The Ecology of Technological Progress: How Symbiosis and Competition Affect the Growth of Technology Domains

Science.gov (United States)

Carnabuci, Gianluca

2010-01-01

We show that the progress of technological knowledge is an inherently ecological process, wherein the growth rate of each technology domain depends on dynamics occurring in "other" technology domains. We identify two sources of ecological interdependence among technology domains. First, there are symbiotic interdependencies, implying…

Nuclear structure theory. Annual technical progress report, July 1, 1975--September 30, 1976

International Nuclear Information System (INIS)

French, J.B.; Koltun, D.S.

1976-01-01

This report summarizes progress during the past year in the following areas of nuclear structure and reaction theory: Meson interactions with nucleons and nuclei, including elastic and inelastic scattering of pions, three-body theories of scattering and absorption of pions by deuterons, π-p bremsstrahlung, and multiple-excitation models for meson absorption by heavier nuclei. Studies of the inverse scattering problem including 1 S 0 nucleon-nucleon scattering; the relativistic two-body problem, particularly for relativistic effects at low energies: the unitary-pole expansion in nucleon-nucleon scattering with hard-core interactions. Statistical spectroscopy including: strength distributions and sum rules(both energy weighted and inverse energy weighted) for nuclear excitations; fluctuations and correlations in spectra, strengths and expectation values; studies of Garvey-Kelson and similar mass relationships; spectroscopy in huge spaces including spectral methods for renormalization of the interaction and for using (two + three)-body Skyrme interactions; technical aspects of operator averaging

Flat-plate solar array progress and plans

Science.gov (United States)

Callaghan, W. T.; Henry, P. K.

1984-01-01

The Flat-Plate Solar Array Project (FSA), sponsored by the U.S. Department of Energy (DOE) and managed by the Jet Propulsion Laboratory (JPL), has achieved progress in a broad range of technical activities since that reported at the Fourth European Communities Conference. A particularly important analysis has been completed recently which confirms the adoption into practice by the U.S. Photovoltaic (PV Industry, of all the low-cost module technology elements proposed at the 16th Project Integration Meeting for a $2.80/Wp (1980 U.S. Dollars) design approach in the fall of 1980. This work presents along with a projection, using the same techniques, for what is believed to be a very credible ribbon-based module design for less that $0.55/Wp (1980 U.S. Dollars). Other areas to be reported upon include low-cost Si feedstock refinement; ribbon growth; process sequence development for cells; environmental isolation; engineering science investigations; and module testing progress.

Growth hormone treatment and risk of recurrence or progression of brain tumors in children: a review.

Science.gov (United States)

Bogarin, Roberto; Steinbok, Paul

2009-03-01

Brain tumors are one of the most common types of solid neoplasm in children. As life expectancy of these patients has increased with new and improved therapies, the morbidities associated with the treatments and the tumor itself have become more important. One of the most common morbidities is growth hormone deficiency, and since recombinant growth hormone (GH) became available, its use has increased exponentially. There is concern that in the population of children with brain tumors, GH treatment might increase the risk of tumor recurrence or progression or the appearance of a second neoplasm. In the light of this ongoing concern, the current literature has been reviewed to provide an update on the risk of tumor recurrence, tumor progression, or new intracranial tumor formation when GH is used to treat GH deficiency in children, who have had or have intracranial tumors. On the basis of this review, the authors conclude that the use of GH in patients with brain tumor is safe. GH therapy is not associated with an increased risk of central nervous system tumor progression or recurrence, leukemia (de novo or relapse), or extracranial non-leukemic neoplasms.

Technical solutions to enable embedded generation growth

Energy Technology Data Exchange (ETDEWEB)

Lynch, C.A.; Todd, S.; Millar, W.; Wood, H.S.

2003-07-01

This report describes the results of one of a series of studies commissioned by the UK Department of Trade and Industry into various aspects of embedded generation with the aim of supporting the development and deployment of electrical sources (particularly their ease of connection to the network) to deliver power to consumers. The first phase of the project involved a literature review and meetings with embedded generation developers and planning engineers from distribution network operators (DNOs). The second phase investigated embedded generation at different levels of the distribution network and included modelling a representative network. Technologies that could facilitate a significant increase in embedded generation were identified and estimates made of when and where significant development would be needed. Technical problems identified by DNOs were concerned with thermal loading, voltage regulation, fault levels, protection and network operation. A number of non-technical (commercial and regulatory) problems were also identified. The report describes the UK regulatory framework, the present situation, the British power system, the accommodation of embedded generation by established means, the representative model and technical innovations.

Nuclear waste glass melter: an update of technical progress

International Nuclear Information System (INIS)

Brouns, R.A.; Hanson, M.S.

1984-08-01

The direct slurry-fed ceramic-lined melter is currently the reference US process for treating defense and civilian high-level liquid waste. Extensive nonradioactive pilot-scale testing at Pacific Northwest Laboratory (PNL) and Savannah River Laboratory has proven the process, defined operating parameters, and identified successful equipment design concepts. Programs at PNL continue to support several of the planned US vitrification plants through preparation of equipment designs and flowsheet testing. Current emphasis is on remotization of equipment, radioactive verification testing, and resolution of remaining technical issues. Development of this technology, technical status, and planned development activities are discussed. 9 references, 4 figures

THE CORRELATION BETWEEN RESEARCH AND DEVELOPMENT AND THE ECONOMIC GROWTH IN ROMANIA

Directory of Open Access Journals (Sweden)

Dragomir Laurentiu

2008-05-01

Full Text Available The increasing productivity of production factors, due to progresses in science and technology is today the engine of economic growth. The economic theory managed to endogenize the technical progress, first as a result of the unintended activities of firms, then as the result of profit driven behaviour of economic agents. In globalization the stock of knowledge becomes available also to developing countries and the production technologies and their employment are more democratic regarding the availability. For the developing countries it still remains the problem of financial resources and availability. Developing new technologies has a prohibitive costs, at least until the moment in which large scale production allows for the reduction of costs. Long term economic growth will depend on the creation of global technology stock, including the leverage effect of sustained RxD. In this paper we will approach the progress of Romania in the area of knowledge base economy, especially regarding the policies in the RxD sector.

ZnO growth technologies: current status and perspectives

International Nuclear Information System (INIS)

Lupan, Oleg

2011-01-01

Development of new technologies for ZnO nano materials and thin films is of critical importance for further fundamental investigations and practical applications. We discuss on the main technical control of the synthesis of zinc oxide and its properties, which are of significance in understanding the growth mechanism and further developing ZnO-based devices. Next, we present a brief summary of recent research activities, current status and progress in developing improved control of technological processes for zinc oxide as advanced material.

Productivity growth and technological progress in the Brazilian agricultural sector

Directory of Open Access Journals (Sweden)

Marcelo Farid Pereira

2002-12-01

Full Text Available Starting in the 1970's, the Brazilian agricultural sector has experienced an important process of modernization, whose principal effects include advances in technological progress and gains in productivity. The primary objective of this paper is to analyze technological progress and total productivity growth in the Brazilian agricultural sector during the period from 1970 to 1996. The methodology used here is based on the Malmquist productivity index and techniques in mathematical programming called Data Envelopment Analysis. The results show that significant progress was made in this sector of the economy but concentrated in only some regions of the country.O setor agropecuário brasileiro passou por um processo de modernização a partir dos anos 70, conseqüentemente, espera-se que exista uma contrapartida de progresso tecnológico e de ganhos de produtividade para o setor. Diante de tal fato tem-se como objetivo, neste estudo, avaliar o progresso tecnológico e o crescimento da produtividade total dos fatores (PTF do setor agropecuário brasileiro ao longo do período de 1970 a 1996. A metodologia utilizada foi baseada no índice Malmquist de produtividade e nas técnicas de programação matemática denominadas de Análise de Envoltória de Dados (DEA. Os resultados alcançados foram condizentes com estudos prévios e apontam para progresso técnico e ganhos de produtividade para o setor, porém concentrados em algumas regiões.

48 CFR 2052.211-70 - Preparation of technical reports.

Science.gov (United States)

2010-10-01

....211-70 Preparation of technical reports. As prescribed at 2011.104-70(a), the contracting officer... Reports (JAN 1993) All technical reports required by Section C and all Technical Progress Reports required... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Preparation of technical...

FY13 Annual Progress Report for SECA Core Technology Program

Energy Technology Data Exchange (ETDEWEB)

Stevenson, Jeffry W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Koeppel, Brian J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

2014-01-31

This progress report covers technical work performed during fiscal year 2013 at PNNL under Field Work Proposal (FWP) 40552. The report highlights and documents technical progress in tasks related to advanced cell and stack component materials development and computational design and simulation.

The challenge of the future. Technical progress and ecological perspectives

International Nuclear Information System (INIS)

Jischa, M.F.

1993-01-01

The book introduces readers into the interrelated global problems population dynamics, energy supply, imminent climate catastrophe, environmetal pollution, finite resources and the conflict between the North and South. It encourages probing more deeply into the technical challenges of the future. The author demonstrates why economic and technical issues will soon be outstripped by questions of the environmental, human and social compatibility of new technologies. (orig./UA) [de

AGRO-ECONOMICAL ASPECTS OF GROWTH STIMULANTS AND MICROFERTILIZERS APPLICATION ON BUCKWHEAT

OpenAIRE

Kozlobaeva E. A.; Kozlobaev A. V.

2015-01-01

The article highlights the food value of buckwheat. It is said that the achievement of its biological potential under prevailing conditions of cultivation is impossible without the introduction of modern scientific and technical progress. The authors describe variants of integrated application of growth stimulants and microfertilizers in buckwheat production technology. Recommended technologies have been tested in conditions of the Central Chernozem region. It is revealed that the best varian...

Periodic progress report, 6 months

DEFF Research Database (Denmark)

Juhl, Thomas Winther; Nielsen, Jakob Skov

This is the first progress report of the BriteEuram project named "High Power Laser Cutting for Heavy Industry" ("Powercut"). The report contains a summary of the objectives of the first period, an overview of the technical progress, a comparison between the planed and the accomplished work...

How Stock Markets Development Affect Endogenous Growth Theory

Directory of Open Access Journals (Sweden)

Najeb Masoud

2013-10-01

Full Text Available This paper can bedescribed as a significant exploratory study that will provide a significantcontribution to knowledge to consider crucial issues which need to be barriersto understanding or a temptation/ requirement to judge some practices as‘better’ than others for stock market development effective approach andimplement successful stock market performance and economic growth. Recentanalysis of the link between financial development and growth, gained frominsights acquired as a result of using the technique of endogenous growthmodels, has illustrated that growth without exogenous technical progress andthat growth rates could be related to technology, income distribution andinstitutional arrangements. This provides the theoretical background thatempirical studies have lacked; illustrating that financial intermediationaffects the level of economic growth. Resulting models have provided newimpetus to empirical research of the effects of financial development. Thebirth of the new endogenous growth theory has facilitated the development ofimproved growth models where the long-term rate could be affected by a numberof elements. These included technology, education and health policies in theprocess of economic development, capital accumulation, government policies andinstitutional activities in the role of financial development in economicgrowth.

Construction of LDPC codes over GF(q) with modified progressive edge growth

Institute of Scientific and Technical Information of China (English)

CHEN Xin; MEN Ai-dong; YANG Bo; QUAN Zi-yi

2009-01-01

A parity check matrix construction method for constructing a low-density parity-check (LDPC) codes over GF(q) (q>2) based on the modified progressive edge growth (PEG) algorithm is introduced. First, the nonzero locations of the parity check matrix are selected using the PEG algorithm. Then the nonzero elements are defined by avoiding the definition of subcode. A proof is given to show the good minimum distance property of constructed GF(q)-LDPC codes. Simulations are also presented to illustrate the good error performance of the designed codes.

Transforming Growth Factor-Beta and Oxidative Stress Interplay: Implications in Tumorigenesis and Cancer Progression

Science.gov (United States)

Krstić, Jelena; Trivanović, Drenka; Mojsilović, Slavko; Santibanez, Juan F.

2015-01-01

Transforming growth factor-beta (TGF-β) and oxidative stress/Reactive Oxygen Species (ROS) both have pivotal roles in health and disease. In this review we are analyzing the interplay between TGF-β and ROS in tumorigenesis and cancer progression. They have contradictory roles in cancer progression since both can have antitumor effects, through the induction of cell death, senescence and cell cycle arrest, and protumor effects by contributing to cancer cell spreading, proliferation, survival, and metastasis. TGF-β can control ROS production directly or by downregulating antioxidative systems. Meanwhile, ROS can influence TGF-β signaling and increase its expression as well as its activation from the latent complex. This way, both are building a strong interplay which can be taken as an advantage by cancer cells in order to increment their malignancy. In addition, both TGF-β and ROS are able to induce cell senescence, which in one way protects damaged cells from neoplastic transformation but also may collaborate in cancer progression. The mutual collaboration of TGF-β and ROS in tumorigenesis is highly complex, and, due to their differential roles in tumor progression, careful consideration should be taken when thinking of combinatorial targeting in cancer therapies. PMID:26078812

La teoria neoclassica della crescita e della distribuzione (Neoclassical Theory of growth and Income Distribution

Directory of Open Access Journals (Sweden)

Robert M. Solow

2000-05-01

Full Text Available The paper surveys the neoclassical theory of growth. As a preliminary, the meaning of the adjective "neoclassical" is discussed. The basic model is then sketched, and the conditions ensuring a stationary state are illustrated. The issue of the convergence to a stationary state (and that of the speed of convergence is further considered. A discussion of "primary factors" opens the way to the "new" theory of growth, with endogenous technical progress. A number of extensions of the basic model are then recalled: two-sector and multi-sectoral models, overlapping generations models, the role of money in growth models.

PFBC HGCU Test Facility. Technical progress report No. 24, Third quarter, CY 1995

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-10-01

This is the twenty-fourth and final Technical Progress Report submitted to the Department of Energy (DOE) in connection with the cooperative agreement between the DOE and Ohio Power Company for the Tidd PFBC Hot Gas Clean Up Test Facility. This report covers the work completed during the Third Quarter of CY 1995. All activity this quarter was directed toward the completion of the program final report. A draft copy of the final report was forwarded to DOE during this quarter, and DOE submitted their comments on the report to AEPSC. DOE requested that Westinghouse write an appendix to the report covering the performance of the fail-safe regenerator devices during Tad operation, and Westinghouse subsequently prepared the appendix. Additional DOE comments were incorporated into the report, and it will be issued in camera-ready form by the end of October, 1995, which is the program end date. Appendix 1 presents the results of filter candle posttest examination by Westinghouse performed on selected filter candles following final shutdown of the system.

A Dominant-Negative PPARγ Mutant Promotes Cell Cycle Progression and Cell Growth in Vascular Smooth Muscle Cells

Directory of Open Access Journals (Sweden)

Joey Z. Liu

2009-01-01

Full Text Available PPARγ ligands have been shown to have antiproliferative effects on many cell types. We herein report that a synthetic dominant-negative (DN PPARγ mutant functions like a growth factor to promote cell cycle progression and cell proliferation in human coronary artery smooth muscle cells (CASMCs. In quiescent CASMCs, adenovirus-expressed DN-PPARγ promoted G1→S cell cycle progression, enhanced BrdU incorporation, and increased cell proliferation. DN-PPARγ expression also markedly enhanced positive regulators of the cell cycle, increasing Rb and CDC2 phosphorylation and the expression of cyclin A, B1, D1, and MCM7. Conversely, overexpression of wild-type (WT or constitutively-active (CA PPARγ inhibited cell cycle progression and the activity and expression of positive regulators of the cell cycle. DN-PPARγ expression, however, did not up-regulate positive cell cycle regulators in PPARγ-deficient cells, strongly suggesting that DN-PPARγ effects on cell cycle result from blocking the function of endogenous wild-type PPARγ. DN-PPARγ expression enhanced phosphorylation of ERK MAPKs. Furthermore, the ERK specific-inhibitor PD98059 blocked DN-PPARγ-induced phosphorylation of Rb and expression of cyclin A and MCM7. Our data thus suggest that DN-PPARγ promotes cell cycle progression and cell growth in CASMCs by modulating fundamental cell cycle regulatory proteins and MAPK mitogenic signaling pathways in vascular smooth muscle cells (VSMCs.

Sequential purification and crystal growth for the production of low cost silicon substrates. Quarterly technical progress report No. 1, 15 September 1979-31 December 1979

Energy Technology Data Exchange (ETDEWEB)

Liaw, M.; Secco, F.; Ingle, B.; Down, D.

1980-02-01

Over the past several years, Motorola's Materials Technology Laboratory (MTL), has been conducting several projects with goals directed at the production of high quality low cost silicon crystals. One of the projects which is being investigated is the direct purification of MG-Si. A unique characteristic of the approach used by this project is the use of a crystal puller to perform both purification and crystal growth. Sequential steps of purification were taken. By the completion of this series of purification, the purified MG-Si melt will be further purified by impurity redistribution using ingot pulling. The final purified silicon will be in an ingot form of desired dimensions for slicing into silicon sheets. The sequential steps of purification include: (1) leaching of MG-Si charge, (2) phase separation, (3) reactive gas treatment, (4) liquid-liquid extraction (called Slagging), and (5) purification by redistribution of impurities using ingot pulling. Progress on items (1) and (2) is reported. (WHK)

Appropriability, Technological Opportunity, Market Demand, and Technical Change - Empirical Evidence from Switzerland

OpenAIRE

Harabi, Najib

1992-01-01

The purpose of this paper is to analyze both theoretically and empirically those factors which underlay the - empirically observable - inter-industry differences in technical progress. At the theoretical level economists agree more and more that technical progress can be explained at the industry level by the following three factors: (1) the technological opportunities, (2) the appropriability conditions, meaning the ability to capture and protect the results of technical innovations and (3) ...

High temperature turbine technology program. Phase II. Technology test and support studies. Annual technical progress report, January 1, 1979-December 31, 1979

Energy Technology Data Exchange (ETDEWEB)

1980-01-01

Work performed on the High Temperature Turbine Technology Program, Phase II - Technology Test and Support Studies during the period from January 1, 1979 through December 31, 1979 is summarized. Objectives of the program elements as well as technical progress and problems encountered during this Phase II annual reporting period are presented. Progress on design, fabrication and checkout of test facilities and test rigs is described. LP turbine cascade tests were concluded. 350 hours of testing were conducted on the LP rig engine first with clean distillate fuel and then with fly ash particulates injected into the hot gas stream. Design and fabrication of the turbine spool technology rig components are described. TSTR 60/sup 0/ sector combustor rig fabrication and testing are reviewed. Progress in the design and fabrication of TSTR cascade rig components for operation on both distillate fuel and low Btu gas is described. The new coal-derived gaseous fuel synthesizing facility is reviewed. Results and future plans for the supporting metallurgical programs are discussed.

GPHS-RTGs in support of the Cassini mission. Semi annual technical progress report, 2 October 1995--31 March 1996

International Nuclear Information System (INIS)

1996-01-01

The technical progress achieved during the period 2 October 1995 through 31 March 1996 on Contract No. DE-AC03-91SF18852, Radioisotope Generators and Ancillary Activities is described herein. This report is organized by the program task structure as follows: spacecraft integration and liaison; engineering support; safety; qualified unicouple fabrication; ETG fabrication, assembly, and test; ground support equipment (GSE); RTG shipping and launch support; designs, reviews, and mission applications; project management, quality assurance and reliability, contract changes, non-capital CAGO acquisition, and CAGO maintenance; contract acquired government-owned property (CAGO) acquisition; and program calendars

ISABELLE: a progress report

Energy Technology Data Exchange (ETDEWEB)

Hahn, H

1980-01-01

This paper discusses the ISABELLE project, which has the objective of constructing a high-energy proton colliding beam facility at Brookhaven National Laboratory. The major technical features of the intersecting storage accelerators with their projected performance are described. Application of over 1000 superconducting magnets in the two rings represents the salient characteristic of the machine. The status of the entire project, the technical progress made so far, and difficulties encountered are reviewed.

ISABELLE: a progress report

International Nuclear Information System (INIS)

Hahn, H.

1980-01-01

This paper discusses the ISABELLE project, which has the objective of constructing a high-energy proton colliding beam facility at Brookhaven National Laboratory. The major technical features of the intersecting storage accelerators with their projected performance are described. Application of over 1000 superconducting magnets in the two rings represents the salient characteristic of the machine. The status of the entire project, the technical progress made so far, and difficulties encountered are reviewed

Role for transforming growth factor-beta1 in alport renal disease progression.

Science.gov (United States)

Sayers, R; Kalluri, R; Rodgers, K D; Shield, C F; Meehan, D T; Cosgrove, D

1999-11-01

Alport syndrome results from mutations in either the alpha3(IV), alpha4(IV), or alpha5(IV) collagen genes. The disease is characterized by a progressive glomerulonephritis usually associated with a high-frequency sensorineural hearing loss. A mouse model for an autosomal form of Alport syndrome [collagen alpha3(IV) knockout] was produced and characterized. In this study, the model was exploited to demonstrate a potential role for transforming growth factor-beta1 (TGF-beta1) in Alport renal disease pathogenesis. Kidneys from normal and Alport mice, taken at different stages during the course of renal disease progression, were analyzed by Northern blot, in situ hybridization, and immunohistology for expression of TGF-beta1 and components of the extracellular matrix. Normal and Alport human kidney was examined for TGF-beta1 expression using RNase protection. The mRNAs encoding TGF-beta1 (in both mouse and human), entactin, fibronectin, and the collagen alpha1(IV) and alpha2(IV) chains were significantly induced in total kidney as a function of Alport renal disease progression. The induction of these specific mRNAs was observed in the glomerular podocytes of animals with advanced disease. Type IV collagen, laminin-1, and fibronectin were markedly elevated in the tubulointerstitium at 10 weeks, but not at 6 weeks, suggesting that elevated expression of specific mRNAs on Northern blots reflects events associated with tubulointerstitial fibrosis. The concomitant accumulation of mRNAs encoding TGF-beta1 and extracellular matrix components in the podocytes of diseased kidneys may reflect key events in Alport renal disease progression. These data suggest a role for TGF-beta1 in both glomerular and tubulointerstitial damage associated with Alport syndrome.

The general technical regulation and the standardization

International Nuclear Information System (INIS)

Laverie, Michel; Houze, Christian; Lebouleux, Philippe

1980-01-01

Through a certain number of procedures, the thorough appreciation of the safety of a nuclear installation relies more on a specific appreciation taking into account the references as a whole, than on a technical regulation which claims to cover all the problems. Nevertheless, a French technical regulation structure regarding the safety domain must be built up progressively. The authors consider the principles of such a structure, and together they make the inventory of the works, finished, in progress or contemplated. The description of this specifically French approach emphazises the multiple and complementary forms given to statutory implements [fr

Non-technical constraints to eradication: the Italian experience.

Science.gov (United States)

Moda, Giuliana

2006-02-25

Although technical constraints to eradication of bovine tuberculosis are well-recognised, non-technical constraints can also delay progress towards eradication, leading to inefficiency and increased programme costs. This paper seeks to analyse the main non-technical constraints that can interfere with the successful implementation of tuberculosis eradication plans, based on experiences from an area of high tuberculosis prevalence in Regione Piemonte, Italy. The main social and economic constraints faced in the past 20 years are reviewed, including a social reluctance to recognise the importance of seeking eradication as the goal of disease control, effective communication of technical issues, the training and the organization of veterinary services, the relationship between the regional authority and farmers and their representatives, and data management and epidemiological reporting. The paper analyses and discusses the solutions that were applied in Regione Piemonte and the benefits that were obtained. Tuberculosis eradication plans are one of the most difficult tasks of the Veterinary Animal Health Services, and non-technical constraints must be considered when progress towards eradication is less than expected. Organizational and managerial resources can help to overcome social or economic obstacles, provided the veterinary profession is willing to address technical, but also non-technical, constraints to eradication.

From scientific progress to economic growth the economics and the economy of science

CERN Document Server

Witte, Frank

2017-01-01

he past few centuries have seen an enormous increase in living standards in many parts of the world and these economies have become more complex than ever before. At the same time, progress in science and technology has reached unprecedented heights, taking us far beyond the wildest dreams of a few generations ago. Questions as to how science, technology and the economy interact are pertinent and important ones, whose partial answers require a view "from across the fence" between disciplines. This book provides an introduction to the vast and varied field of the economics of science. It is a unique blend of an economic perspective on the way science works, what makes scientists tick, and a study of the impact of scientific and technological progress on economies and their growth. Whether it is about the speculative market of ideas or science and technology as engines of the economy, there is something here for economists, engineers and scientists alike.

TECHNICAL COORDINATION

CERN Multimedia

A. Ball and W. Zeuner

2011-01-01

In this report we will review the main achievements of the Technical Stop and the progress of several centrally-managed projects to support CMS operation and maintenance and prepare the way for upgrades. Overview of the extended Technical Stop  The principal objectives of the extended Technical Stop affecting the detector itself were the installation of the TOTEM T1 telescopes on both ends, the readjustment of the alignment link-disk in YE-2, the replacement of the light-guide sleeves for all PMs of both HFs, and some repairs on TOTEM T2 and CASTOR. The most significant tasks were, however, concentrated on the supporting infrastructure. A detailed line-by-line leak search was performed in the C6F14 cooling system of the Tracker, followed by the installation of variable-frequency drives on the pump motors of the SS1 and SS2 tracker cooling plants to reduce pressure transients during start-up. In the electrical system, larger harmonic filters were installed in ...

Effects of humic substances on the migration of radionuclides: complexation and transport of actinides. First technical progress report (work period 01.97 - 12.97)

International Nuclear Information System (INIS)

Buckau, G.

1998-08-01

The present report describes progress within the first year of the EC-project 'Effects of Humic Substances on the Migration of Radionuclides: Complexation and Transport of Actinides'. The project is conducted within the EC-Cluster 'Radionuclide Transport/Retardation Processes'. Contrary to formal requirements of the Commission, this report with a great deal of detail is established already after one year of project work. It is scheduled to be followed by a second technical progress report covering the second year of the project. In agreement with the contractual obligations a final report of similar technical detail will also be generated. The report contains an executive summary written by the coordinator (FZK/INE) with strong support from the other three task leaders (BGS, CEA-SGC and RMC-E). More detailed results are given by individual contributions of the project partners in 13 annexes. In the executive summary report the origin of results presented is given, also serving as guidance for finding more detailed results in the annexes. Not all results are discussed or referred to in the executive summary report and thus readers with a deeper interest also need to consult the annexes. (orig.)

Effect of progressive drought stress on growth, leaf gas exchange, and antioxidant production in two maize cultivars.

Science.gov (United States)

Anjum, Shakeel Ahmad; Tanveer, Mohsin; Ashraf, Umair; Hussain, Saddam; Shahzad, Babar; Khan, Imran; Wang, Longchang

2016-09-01

Drought stress is one of the major environmental factors responsible for reduction in crop productivity. In the present study, responses of two maize cultivars (Rung Nong 35 and Dong Dan 80) were examined to explicate the growth, yield, leaf gas exchange, leaf water contents, osmolyte accumulation, membrane lipid peroxidation, and antioxidant activity under progressive drought stress. Maize cultivars were subjected to varying field capacities (FC) viz., well-watered (80 % FC) and drought-stressed (35 % FC) at 45 days after sowing. The effects of drought stress were analyzed at 5, 10, 15, 20, ad 25 days after drought stress (DAS) imposition. Under prolonged drought stress, Rung Nong 35 exhibited higher reduction in growth and yield as compared to Dong Dan 80. Maize cultivar Dong Dan 80 showed higher leaf relative water content (RWC), free proline, and total carbohydrate accumulation than Run Nong 35. Malondialdehyde (MDA) and superoxide anion were increased with prolongation of drought stress, with higher rates in cultivar Run Nong 35 than cultivar Dong Dan 80. Higher production of superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) and glutathione reductase (GR) resulted in improved growth and yield in Dong Dan 80. Overall, the cultivar Dong Dan 80 was better able to resist the detrimental effects of progressive drought stress as indicated by better growth and yield due to higher antioxidant enzymes, reduced lipid peroxidation, better accumulation of osmolytes, and maintenance of tissue water contents.

Building Professional and Technical Skills in the Use of Earth Observations through the NASA DEVELOP National Program: Best Practices & Lessons Learned

Science.gov (United States)

Crepps, G.; Ross, K. W.; Childs-Gleason, L. M.; Allsbrook, K. N.; Rogers, L.; Ruiz, M. L.; Clayton, A.

2017-12-01

The NASA DEVELOP National Program offers 10-week research opportunities to participants to work on rapid feasibility projects utilizing NASA Earth observations in a variety of applications, including ecological forecasting, water resources, disasters, and health and air quality. DEVELOP offers a unique collaborative environment in which students, recent graduates, and transitioning career professionals are placed on interdisciplinary teams to conduct projects. DEVELOP offers a variety of opportunities and resources to build participants technical skills in remote sensing and GIS, as well as interpersonal and leadership skills. As a capacity building program, DEVELOP assesses participants' growth by using entrance and exit personal growth assessments, as well as gathering general program feedback through an exit survey. All of this information is fed back into the program for continual improvement. DEVELOP also offers a progression of opportunities through which participants can advance through the program, allowing participants to build a diverse set of technical and leadership skills. This presentation will explore best practices including the use of pre- and post-growth assessments, offering advanced leadership opportunities, and overall capacity building impacts on participants.

La teoria neoclassica della crescita e della distribuzione (Neoclassical Theory of growth and Income Distribution

Directory of Open Access Journals (Sweden)

Robert M. Solow

2012-10-01

Full Text Available The paper surveys the neoclassical theory of growth. As a preliminary, the meaning of the adjective "neoclassical" is discussed. The basic model is then sketched, and the conditions ensuring a stationary state are illustrated. The issue of the convergence to a stationary state (and that of the speed of convergence is further considered. A discussion of "primary factors" opens the way to the "new" theory of growth, with endogenous technical progress. A number of extensions of the basic model are then recalled: two-sector and multi-sectoral models, overlapping generations models, the role of money in growth models.       JEL Codes: O41, E25Keywords: Distribution, Growth, Income Distribution, Income

Progress Report Oct to Dec 1975(2)

International Nuclear Information System (INIS)

1976-01-01

Progress report NO. 2 of Tehran Nuclear Research Centre outlines a brief description of the progress made in each section of the centre. A complete list of dissertations for Master's degrees studied at the Nuclear Research Centre and a list of new technical employee are given at the beginning of the report. Research activities in the third section include, isotope separation, laser research, radiation chemistry, reactor management, environmental research, neutron physics, reactor engineering, and nuclear medicine. The fourth section deals with education and training; technical support and health physics are discussed in sections five and six respectively

Progress report for '89

International Nuclear Information System (INIS)

Podest, M.

1990-08-01

The 1989 Progress Report presents the most important scientific and technical achievements of the Nuclear Research Institute's research work. Some specialized products prepared at or fabricated by the NRI are mentioned as well. (author). 24 figs., 8 tabs., 101 refs

C-Mod Collaboration Informal Technical Progress Report

International Nuclear Information System (INIS)

Kenneth W. Gentle

2007-01-01

The aims of the collaboration have not changed. A specific list of tasks was agreed upon during the Fall of 2006 in preparation for the 2007 C-Mod campaign by Earl Marmar, Head of the Alcator Project, Kenneth Gentle, Principal Investigator, and William Rowan, Collaboration Coordinator with the facilitation of Adam Rosenberg (DOE grant monitor for the collaboration). The activities follow the list of tasks and are discussed in this progress report

The Golden Age of Technical Communication

Science.gov (United States)

Kimball, Miles A.

2017-01-01

This article uses a historical perspective to describe the development of the profession of technical communication through three ages: Brass, Beige, and Glass. I compare this development to the growth of the academic discipline and both to the explosion of noninstitutional technical communication--the growing body of tactical technical…

Progress report 1979

International Nuclear Information System (INIS)

1980-12-01

This progress report deals with technical and research work done at the AAEC Research Establishment in the twelve month period ending September 30, 1979. Work done in the following research divisions is reported: Applied Maths and Computing, Chemical Technology, Engineering Research, Environmental Science, Instrumentation and Control, Isotope, Materials and Physics

Insulin-Like Growth Factor-1 Inscribes a Gene Expression Profile for Angiogenic Factors and Cancer Progression in Breast Epithelial Cells

Directory of Open Access Journals (Sweden)

J.S. Oh

2002-01-01

Full Text Available Activation of the insulin-like growth factor-1 receptor (IGF-11R by IGF-1 is associated with the risk and progression of many types of cancer, although despite this it remains unclear how activated IGF-1 R contributes to cancer progression. In this study, gene expression changes elicited by IGF-1 were profiled in breast epithelial cells. We noted that many genes are functionally linked to cancer progression and angiogenesis. To validate some of the changes observed, the RNA and/or protein was confirmed for c-fos, cytochrome P4501Al, cytochrome P450 1131, interleukin-1 beta, fas ligand, vascular endothelial growth factor, and urokinase plasminogen activator. Nuclear proteins were also temporally monitored to address how gene expression changes were regulated. We found that IGF-1 stimulated the nuclear translocation of phosphorylated AKT, hypoxic-inducible factor-1 alpha, and phosphorylated cAMP-responsive element-binding protein, which correlated with temporal changes in gene expression. Next, the promoter regions of IGF-1-regulated genes were searched in silico. The promoters of genes that clustered together had similar regulatory regions. In summary, IGF-1 inscribes a gene expression profile relevant to cancer progression, and this study provides insight into the mechanism(s whereby some of these changes occur.

Progress report [of] Technical Physics Division

International Nuclear Information System (INIS)

Vijendran, P.; Deshpande, R.Y.

1975-01-01

Activities of the Technical Physics Division of the Bhabha Atomic Research Centre, Bombay, over the last few years are reported. This division is engaged in developing various technologies supporting the development of nuclear technology. The various fields in which development is actively being carried out are : (i) vacuum technology, (ii) mass spectrometry, (iii) crystal technology, (iv) cryogenics, and (v) magnet technology. For surface studies, the field emission microscope and the Auger electron spectrometer and other types of spectrometers have been devised and perfected. Electromagnets of requisite strength to be used in MHD programme and NMR instruments are being fabricated. Various crystals such as NaI(Tl), Ge, Fluorides, etc. required as windows and prisms in X and gamma-ray spectroscopy, have been grown. In the cryogenics field, expansion engines required for air liquefaction plants, vacuum insulated dewars, helium gas thermometers etc. have been constructed. In addition to the above, the Division provides consultancy and training to personnel from various institutions and laboratories. Equipment and systems perfected are transferred to commercial organizations for regular production. (A.K.)

The development of an e-learning software, ''Technical ethics''

International Nuclear Information System (INIS)

Matsue, Kazuki; Madarame, Haruki; Okamoto, Koji

2004-01-01

For the engineers and researchers, it is coming to the time when they are asked not only technical progress but also their ethics view. In this study, I aim to develop of the education software ''Technical Ethics'', which cultivates ethics view of the engineers. (author)

Probabilistic Mass Growth Uncertainties

Science.gov (United States)

Plumer, Eric; Elliott, Darren

2013-01-01

Mass has been widely used as a variable input parameter for Cost Estimating Relationships (CER) for space systems. As these space systems progress from early concept studies and drawing boards to the launch pad, their masses tend to grow substantially, hence adversely affecting a primary input to most modeling CERs. Modeling and predicting mass uncertainty, based on historical and analogous data, is therefore critical and is an integral part of modeling cost risk. This paper presents the results of a NASA on-going effort to publish mass growth datasheet for adjusting single-point Technical Baseline Estimates (TBE) of masses of space instruments as well as spacecraft, for both earth orbiting and deep space missions at various stages of a project's lifecycle. This paper will also discusses the long term strategy of NASA Headquarters in publishing similar results, using a variety of cost driving metrics, on an annual basis. This paper provides quantitative results that show decreasing mass growth uncertainties as mass estimate maturity increases. This paper's analysis is based on historical data obtained from the NASA Cost Analysis Data Requirements (CADRe) database.

Final Technical Report

Energy Technology Data Exchange (ETDEWEB)

John Ross

2003-04-30

The Final Technical Report summarizes research accomplishments and Publications in the period of 5/1/99 to 4/30/03 done on the grant. Extensive progress was made in the period covered by this report in the areas of chemical kinetics of non-linear systems; spatial structures, reaction - diffusion systems, and thermodynamic and stochastic theory of electrochemical and general systems.

Technical reliability of geological disposal for high-level radioactive wastes in Japan. The second progress report. An extra issue: background of the geological disposal

International Nuclear Information System (INIS)

1999-11-01

Based on the Advisory Committee Report on Nuclear Fuel Cycle Backend Policy submitted to the Japanese Government in 1997, JNC documents the progress of research and development program in the form of the second progress report (the first one published in 1992). It summarizes an evaluation of the technical reliability and safety of the geological disposal concept for high-level radioactive wastes (HLW) in Japan. The present document, an extra issue of the progress report, was prepared for the expected readers of the report to have background information on the geological disposal. Thus it gives information about (1) generation of high-level radioactive wastes, (2) history of plans proposed for HLW disposal in Japan, and (3) procedure until the geological disposal plan is finally adopted and basic future schedules. It further discusses on such problems in HLW treatment and disposal, as for example a problem of reliable safety for a very long period. (Ohno, S.)

GT-MHR COMMERCIALZATION STUDY. TECHNICAL PROGRESS AND COST MANAGEMENT REPORT FOR THE PERIOD JUNE 1 THROUGH JUNE 30, 2003

International Nuclear Information System (INIS)

SHENOY, A.S.

2003-01-01

A271 GT-MHR COMMERCIALZATION STUDY TECHNICAL PROGRESS AND COST MANAGEMENT REPORT FOR THE PERIOD JUNE 1 THROUGH JUNE 30, 2003. Petten was provided with irradiation dimensional change data for both fuel compacts and H-451 graphite for design of the graphite sleeves that hold the fuel compacts to be irradiated in HFR-EU2. The Fuel Sample Product Specification for the Fuel Performance Irradiation Test Capsule MHR-2 was completed and approved. A Work Breakdown Structure was prepared for the development and qualification of advanced coated-particle fuels capable of meeting anticipated fuel performance requirements and work was initiated on preparation of schedules and a cost estimates for the test matrices

Electrical and Electronics Technical Team Roadmap

Energy Technology Data Exchange (ETDEWEB)

None

2013-06-01

The Electrical and Electronics Technical Team’s (EETT's) mission is to enable cost-effective, smaller, lighter, and efficient power electronics and electric motors for electric traction drive systems (ETDSs) while maintaining performance of internal combustion engine (ICE)-based vehicles. The EETT also identifies technology gaps, establishes R&D targets, develops a roadmap to achieve technical targets and goals, and evaluates the R&D progress toward meeting the established R&D targets and goals.

Progressive loss of sensitivity to growth control by retinoic acid and transforming growth factor-beta at late stages of human papillomavirus type 16-initiated transformation of human keratinocytes.

Science.gov (United States)

Creek, K E; Geslani, G; Batova, A; Pirisi, L

1995-01-01

Retinoids (vitamin A and its natural and synthetic derivatives) have shown potential as chemopreventive agents, and diets poor in vitamin A and/or its precursor beta-carotene have been linked to an increased risk of cancer at several sites including the cervix. Human papillomavirus (HPV) plays an important role in the etiology of cervical cancer. We have developed an in vitro model of cancer progression using human keratinocytes (HKc) immortalized by HPV16 DNA (HKc/HPV16). Although immortal, early passage HKc/HPV16, like normal HKc, require epidermal growth factor (EGF) and bovine pituitary extract (BPE) for proliferation and undergo terminal differentiation in response to serum and calcium. However, following prolonged culture, growth factor independent HKc/HPV16 lines that no longer require EGF and BPE can be selected (HKc/GFI). Further selection of HKc/GFI produces lines that are resistant to serum- and calcium- induced terminal differentiation (HKc/DR). HKc/DR, but not early passage HKc/HPV16, are susceptible to malignant conversion following transfection with viral Harvey ras or Herpes simplex virus type II DNA. We have investigated the sensitivity of low to high passage HKc/HPV16 and HKc/GFI to growth control by all-trans-retinoic acid (RA, an active metabolite of vitamin A). Early passage HKc/HPV16 are very sensitive to growth inhibition by RA, and in these cells RA decreases the expression of the HPV16 oncogenes E6 and E7. However, as the cells progress in culture they lose their sensitivity to RA. Growth inhibition by RA may be mediated through the cytokine transforming growth factor-beta (TGF-beta), a potent inhibitor of epithelial cell proliferation. RA treatment of HKc/HPV16 and HKc/GFI results in a dose-and time-dependent induction (maximal of 3-fold) in secreted levels of TGF-beta. Also, Northern blot analysis of mRNA isolated from HKc/HPV16 demonstrated that RA treatment induced TGF-beta 1 and TGF-beta 2 expression about 3- and 50-fold, respectively

Generalization of international centrifugal zone growth of metal-ceramic composites. Technical report

Energy Technology Data Exchange (ETDEWEB)

Sekerka, R.F.; Hartzell, R.A.

1976-08-01

The electric and temperature fields within inductively heated materials have been calculated in order to better understand the essential features of the crystal growth process called Internal Centrifugal Zone Growth (ICZG). A complicated two-dimensional problem has been studied via a simple one-dimensional model which applies to infinitely long samples heated by infinitely long induction coils. Two such one-dimensional models are presented. In the first model, all material properties of the sample are assumed to be independent of temperature. The coupled differential equations determining the electric field and temperature distributions within the sample are solved analytically. Resulting profiles of temperature and electromagnetic fields within the sample provide a basis for more sophisticated models. The second model deals with materials (e.g., oxides) whose electrical conductivities are very low at room temperature but increase significantly with temperature. The differential equations for electromagnetic and temperature fields are consequently strongly coupled, resulting in multiple steady state solutions, some of which are unstable. An understanding of this instability is of utmost importance with regard to crystal growth via ICZG, because it has been observed that an increase in the electrical conductivity of the sample when melting occurs can cause a catastrophic increase in surface temperature. The modeling predicts, however, that the instability can be controlled through a judicious choice of RF frequency, sample size, and sample alloying. Progress has been made in solving the two-dimensional differential equations. Many problems are encountered that are not present in one-dimensional modeling. The method of solution is outlined, but no solutions have yet been obtained.

Generalization of international centrifugal zone growth of metal-ceramic composites. Technical report

International Nuclear Information System (INIS)

Sekerka, R.F.; Hartzell, R.A.

1976-08-01

The electric and temperature fields within inductively heated materials have been calculated in order to better understand the essential features of the crystal growth process called Internal Centrifugal Zone Growth (ICZG). A complicated two-dimensional problem has been studied via a simple one-dimensional model which applies to infinitely long samples heated by infinitely long induction coils. Two such one-dimensional models are presented. In the first model, all material properties of the sample are assumed to be independent of temperature. The coupled differential equations determining the electric field and temperature distributions within the sample are solved analytically. Resulting profiles of temperature and electromagnetic fields within the sample provide a basis for more sophisticated models. The second model deals with materials (e.g., oxides) whose electrical conductivities are very low at room temperature but increase significantly with temperature. The differential equations for electromagnetic and temperature fields are consequently strongly coupled, resulting in multiple steady state solutions, some of which are unstable. An understanding of this instability is of utmost importance with regard to crystal growth via ICZG, because it has been observed that an increase in the electrical conductivity of the sample when melting occurs can cause a catastrophic increase in surface temperature. The modeling predicts, however, that the instability can be controlled through a judicious choice of RF frequency, sample size, and sample alloying. Progress has been made in solving the two-dimensional differential equations. Many problems are encountered that are not present in one-dimensional modeling. The method of solution is outlined, but no solutions have yet been obtained

ATR Technical Specification Upgrade Program

International Nuclear Information System (INIS)

McCracken, R.T.; Durney, J.L.; Freund, G.A.

1990-01-01

The Advanced Test Reactor (ATR) is a 250 MW, uranium-aluminum fueled test reactor which began full power operation in 1969. The initial operation was controlled by an Operating Limits document based on the original Safety Analysis Report. Additional safety bases were later developed to support Technical Specifications which were approved and implemented in 1977. The Technical Specifications which were initially developed with content and format specified in ANSI/ANS--15.1, ''The Development of Technical Specifications for Research Reactors.'' The safety basis documentation and the Technical Specifications have been updated as required to maintain them current with the ATR facility configuration. All revisions have been made with a content, format and style consistent with the original. A major, two-phase program to upgrade the content, format and style is in progress. This paper describes the first phase of this program

Technical progress report, 1 April-30 June 1981

Energy Technology Data Exchange (ETDEWEB)

None

1981-01-01

This report describes the technical accomplishments during the quarter ending June 1981, on the commercial nuclear waste management programs under the direction of the Office of Nuclear Waste Isolation (ONWI). The ONWI program is organized into 8 tasks entitled: systems, waste package, site, repository, regulatory and institutional, test facilities and excavations, land acquisition, and program management. Principal investigators in each of these areas have submitted summaries of quarterly highlights for inclusion in this report. Separate abstracts have been prepared for 5 of these tasks for inclusion in the Energy Data Base. (DMC)

Technical progress of nuclear energy: economic and environmental prospects

International Nuclear Information System (INIS)

Naudet, G.

1994-01-01

This document deals with three different aspects of the nuclear energy: first the operating and economic performances of nuclear power plants in the world, the French nuclear competitiveness. Then, the technical and economic perspectives about reactors and fuels cycle and the advantages towards atmospheric pollution are discussed to favour a new worldwide nuclear development. (TEC). 8 refs., 4 figs., 6 tabs

Allelic deletions of cell growth regulators during progression of bladder cancer

DEFF Research Database (Denmark)

Primdahl, H; von der Maase, H; Christensen, M

2000-01-01

Cell growth regulators include proteins of the p53 pathway encoded by the genes CDKN2A (p16, p14arf), MDM2, TP53, and CDKN1A (p21) as well as proteins encoded by genes like RB1, E2F, and MYCL. In the present study we investigated allelic deletions of all these genes in each recurrent bladder tumor...... difference in the numbers of gene loci hit by deletions muscle-invasive versus noninvasive tumors (P = 0.0000002), with the genes most often hit by deletions in muscle-invasive tumors being TP53, RB1, and MYCL. A number of novel findings were made. Losses of MYCL and RB1 alleles were more pronounced...... that a characteristic difference between recurrent noninvasive and recurrent progressing bladder tumors is loss of cell cycle-regulatory genes in the latter group....

Self vs expert assessment of technical and non-technical skills in high fidelity simulation.

Science.gov (United States)

Arora, Sonal; Miskovic, Danilo; Hull, Louise; Moorthy, Krishna; Aggarwal, Rajesh; Johannsson, Helgi; Gautama, Sanjay; Kneebone, Roger; Sevdalis, Nick

2011-10-01

Accurate assessment is imperative for learning, feedback and progression. The aim of this study was to examine whether surgeons can accurately self-assess their technical and nontechnical skills compared with expert faculty members' assessments. Twenty-five surgeons performed a laparoscopic cholecystectomy (LC) in a simulated operating room. Technical and nontechnical performance was assessed by participants and faculty members using the validated Objective Structured Assessment of Technical Skills (OSATS) and the Non-Technical Skills for Surgeons scale (NOTSS). Assessment of technical performance correlated between self and faculty members' ratings for experienced (median score, 30.0 vs 31.0; ρ = .831; P = .001) and inexperienced (median score, 22.0 vs 28.0; ρ = .761; P = .003) surgeons. Assessment of nontechnical skills between self and faculty members did not correlate for experienced surgeons (median score, 8.0 vs 10.5; ρ = -.375; P = .229) or their more inexperienced counterparts (median score, 9.0 vs 7.0; ρ = -.018; P = .953). Surgeons can accurately self-assess their technical skills in virtual reality LC. Conversely, formal assessment with faculty members' input is required for nontechnical skills, for which surgeons lack insight into their behaviours. Copyright © 2011 Elsevier Inc. All rights reserved.

Nuclear theory research. Technical progress report

International Nuclear Information System (INIS)

1982-01-01

Progress is briefly described on the following studies: (1) Dirac phenomenology for deuteron elastic scattering, (2) Dirac wave functions in nuclear distorted wave calculations, (3) impulse approximation for p→p → dπ + reaction above the 3-3 resonance, (4) coherent π production, (5) nuclear potentials from Dirac bound state wavefunctions, (6) nonlocality effects in nuclear reactions, (7) unhappiness factors in DWBA description of (t,p) and (p,t) reactions, (8) absolute normalization of three-nucleon transfer reactions, (9) formulation of a finite-range CCBA computer program, (10) crossing symmetric solutions of the low equations, (11) pion scattering from quark bags, (12) study of the p 11 channel in the delta model, (13) isovector corrections in pion-nucleus scattering, (14) pionic excitation of nuclear giant resonances, and (15) isospin dependence of the second-order pion-nucleus optical potential

Industrial policy, production efficiency improvement and the Chinese county economic growth

Directory of Open Access Journals (Sweden)

Wang Zhenhua

2016-12-01

Full Text Available This study aims at analyzing the difference in the level of economic development between China’s counties from the two perspectives of industrial policy and production efficiency. Based on panel data of 1830 Chinese counties, this study employs the new classical economic growth theory framework to analyze the counties’ economic growth by the perpetual inventory method, Malmquist index, among others. The results show that the economy of the counties exhibits δ convergence since 2004, and the absolute differences in the different counties are expanding. Industrial policy ensures the additional deepening of the level of capital in the county. Additionally, a substantial difference was observed between the agricultural sector and the non-agricultural sector, whereby the total factor productivity and the technical efficiency are on the rise, resulting in the phenomenon of dual paths of technological progress. In summary, the capital deepening difference between the sectors, production efficiency, and dual paths of technological progress owing to the counties’ industrial policy are the basic reasons for the regional differences in the level of economic development in China.

Tumor heterogeneity and progression: conceptual foundations for modeling.

Science.gov (United States)

Greller, L D; Tobin, F L; Poste, G

1996-01-01

A conceptual foundation for modeling tumor progression, growth, and heterogeneity is presented. The purpose of such models is to aid understanding, test ideas, formulate experiments, and to model cancer 'in machina' to address the dynamic features of tumor cell heterogeneity, progression, and growth. The descriptive capabilities of such an approach provides a consistent language for qualitatively reasoning about tumor behavior. This approach provides a schema for building conceptual models that combine three key phenomenological driving elements: growth, progression, and genetic instability. The growth element encompasses processes contributing to changes in tumor bulk and is distinct from progression per se. The progression element subsumes a broad collection of processes underlying phenotypic progression. The genetics elements represents heritable changes which potentially affect tumor character and behavior. Models, conceptual and mathematical, can be built for different tumor situations by drawing upon the interaction of these three distinct driving elements. These models can be used as tools to explore a diversity of hypotheses concerning dynamic changes in cellular populations during tumor progression, including the generation of intratumor heterogeneity. Such models can also serve to guide experimentation and to gain insight into dynamic aspects of complex tumor behavior.

Basalt Waste Isolation Project Technical Program Evaluation Process: a criteria-based method

International Nuclear Information System (INIS)

Babad, H.; Evans, G.C.; Wolfe, B.A.

1982-01-01

The need to objectively evaluate the progress being made by the Basalt Waste Isolation Project (BWIP) toward establishing the feasibility of siting a nuclear waste repository in basalt (NWRB) mandates a process for evaluating the technical work of the project. To assist BWIP management in the evaluation process, the Systems Department staff has developed a BWIP Technical Program Evaluation Process (TPEP). The basic process relates progress on project technical work to the SWIP Functional and System Performance Criteria as defined in National Waste Terminal Storage (MWTS) Criteria Documents. The benefits of the TPEP to BWIP and future plans for TPEP are discussed. During fiscal year (FY) 1982, TPEP wll be further formalized and further applied to the review of BWIP technical activities

Technical Progress Report on Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration

Energy Technology Data Exchange (ETDEWEB)

Bill Stanley; Patrick Gonzalez; Sandra Brown; Jenny Henman; Ben Poulter; Sarah Woodhouse Murdock; Neil Sampson; Tim Pearson; Sarah Walker; Zoe Kant; Miguel Calmon; Gilberto Tiepolo

2006-06-30

The Nature Conservancy is participating in a Cooperative Agreement with the Department of Energy (DOE) National Energy Technology Laboratory (NETL) to explore the compatibility of carbon sequestration in terrestrial ecosystems and the conservation of biodiversity. The title of the research project is ''Application and Development of Appropriate Tools and Technologies for Cost-Effective Carbon Sequestration''. The objectives of the project are to: (1) improve carbon offset estimates produced in both the planning and implementation phases of projects; (2) build valid and standardized approaches to estimate project carbon benefits at a reasonable cost; and (3) lay the groundwork for implementing cost-effective projects, providing new testing ground for biodiversity protection and restoration projects that store additional atmospheric carbon. This Technical Progress Report discusses preliminary results of the six specific tasks that The Nature Conservancy is undertaking to answer research needs while facilitating the development of real projects with measurable greenhouse gas reductions. The research described in this report occurred between April 1st and July 30th 2006. The specific tasks discussed include: Task 1: carbon inventory advancements; Task 2: emerging technologies for remote sensing of terrestrial carbon; Task 3: baseline method development; Task 4: third-party technical advisory panel meetings; Task 5: new project feasibility studies; and Task 6: development of new project software screening tool. Work is being carried out in Brazil, Belize, Chile, Peru and the USA.

Nodal colloid goiter: clinical and morphological criteria of thyroid autonomy and progressive growth

Directory of Open Access Journals (Sweden)

S S Antonova

2006-03-01

Full Text Available Goal. To work up clinical and morphological criteria of thyroid authonomy and progressive growth in nodal colloid goiter (NCG. Methods. A group of patients with nodal euthyroid goiter (NEG (40 patients and a group of patients with nodular toxic goiter (NTG (40 patients were formed to compare clinical and morphological criteria of NCG growth to/with development of functional autonomy (FA. All patients were conducted research including physical examination, thyroid palpation, ultrasound, blood level of TSH and T4, scintigraphy, aspiration (needle biopsy, immunocytological and immunohistological reactions and statistics. In the study the method of indirect immunoperoxidase reaction with monoclonal rat/mouse antigens to Ki-67, TSH, galectin-3, Apo-test (“Dako Corporation”, “Novocastra Laboratories Ltd.” was used. Results. 1. In NEG expression of cell proliferation marker Ki-67 for certain rises pro rata to increase of proliferation degree, and in NTG grows according to FA development. 2. Apoptosis expression in NEG decreases according to degree of thyrocytes in a nodule, but in NTG falls pro rata to accumulation of thyroid FA. 3. Positive reaction for TSH in NEG tissue was found in 100%, whereas negative reaction for this receptor in NTG tissue was observed in 81% of all cases. 4. Galectin-3 was expressed in focuses of severe dysplasia of thyroid nodes tissue comparable to galectin-3 expression in the tissue of high-grade differentiated adenocarcinomas. Summary/conclusion. 1. Severe and moderate expression of Ki-67 and mild or negative immunomorphological reaction for Apo-test allows to refer such kinds of nodules to fast-growing/rapid-growing ones. 2. Reliable negative expression TSH receptor in the tissue of NCG is evidence of FA development and is an indication for a treatment of radioactive iodine or for an operation. 3. Galectin-3 probably is an early marker of malignant transformation in thyroid tissue. 4. Having conducted complex

Overexpression of Insulin-like Growth Factor-1 Receptor Is Associated With Penile Cancer Progression.

Science.gov (United States)

Ball, Mark W; Bezerra, Stephania M; Chaux, Alcides; Faraj, Sheila F; Gonzalez-Roibon, Nilda; Munari, Enrico; Sharma, Rajni; Bivalacqua, Trinity J; Netto, George J; Burnett, Arthur L

2016-06-01

To evaluate insulin-like growth factor-1 receptor (IGF1R) expression in penile cancer and its association with oncologic outcomes. Tissue microarrays were constructed from 53 patients treated at our institution. Expression of IGF1R was evaluated using a Her2-like scoring system. Overexpression was defined as 1+ or greater membranous staining. Association of IGF1R expression with pathologic features was assessed with comparative statistics, and association with local recurrence, progression to nodal or distance metastases, or death was assessed with Kaplan-Meier survival analysis and Cox proportional hazard regression models. Overall, IGF1R overexpression was seen in 33 (62%) cases. With a median follow-up of 27.8 months, IGF1R overexpression was associated with inferior progression-free survival (PFS) (P  =  .003). In a multivariable model controlling for grade, T stage, perineural invasion, and lymphovascular invasion, IGF1R expression was independently associated with disease progression (hazard ratio 2.3, 95% confidence interval 1.1-5.1, P  =  .03. Comparing patients without IGF1R overexpression to those with overexpression, 5-year PFS was 94.1% vs 45.8%. IGF1R overexpression was associated with inferior PFS in penile cancer. Drugs that target IGF1R and downstream messengers may have a therapeutic benefit in patients that exhibit IGF1R overexpression. Copyright © 2016 Elsevier Inc. All rights reserved.

Up-regulation of hepatoma-derived growth factor facilitates tumor progression in malignant melanoma [corrected].

Directory of Open Access Journals (Sweden)

Han-En Tsai

Full Text Available Cutaneous malignant melanoma is the fastest increasing malignancy in humans. Hepatoma-derived growth factor (HDGF is a novel growth factor identified from human hepatoma cell line. HDGF overexpression is correlated with poor prognosis in various types of cancer including melanoma. However, the underlying mechanism of HDGF overexpression in developing melanoma remains unclear. In this study, human melanoma cell lines (A375, A2058, MEL-RM and MM200 showed higher levels of HDGF gene expression, whereas human epidermal melanocytes (HEMn expressed less. Exogenous application of HDGF stimulated colony formation and invasion of human melanoma cells. Moreover, HDGF overexpression stimulated the degree of invasion and colony formation of B16-F10 melanoma cells whereas HDGF knockdown exerted opposite effects in vitro. To evaluate the effects of HDGF on tumour growth and metastasis in vivo, syngeneic mouse melanoma and metastatic melanoma models were performed by manipulating the gene expression of HDGF in melanoma cells. It was found that mice injected with HDGF-overexpressing melanoma cells had greater tumour growth and higher metastatic capability. In contrast, mice implanted with HDGF-depleted melanoma cells exhibited reduced tumor burden and lung metastasis. Histological analysis of excised tumors revealed higher degree of cell proliferation and neovascularization in HDGF-overexpressing melanoma. The present study provides evidence that HDGF promotes tumor progression of melanoma and targeting HDGF may constitute a novel strategy for the treatment of melanoma.

Technical reliability of geological disposal for high-level radioactive wastes in Japan. The second progress report. Part 3. Safety assessment for geological disposal systems

International Nuclear Information System (INIS)

1999-11-01

Based on the Advisory Committee Report on Nuclear Fuel Cycle Backend Policy submitted to the Japanese Government in 1997, JNC documents the progress of research and development program in the form of the second progress report (the first one published in 1992). It summarizes an evaluation of the technical reliability and safety of the geological disposal concept for high-level radioactive wastes (HLW) in Japan. The present document, the part 3 of the progress report, concerns safety assessment for geological disposal systems definitely introduced in part 1 and 2 of this series and consists of 9 chapters. Chapter I concerns the methodology for safety assessment while Chapter II deals with diversity and uncertainty about the scenario, the adequate model and the required data of the systems above. Chapter III summarizes the components of the geological disposal system. Chapter IV refers to the relationship between radioactive wastes and human life through groundwater, i.e. nuclide migration. In Chapter V is made a reference case which characterizes the geological environmental data using artificial barrier specifications. (Ohno. S.)

Career Technical Education Pathways Initiative Annual Report

Science.gov (United States)

California Community Colleges, Chancellor's Office, 2014

2014-01-01

California's education system--the largest in the United States--is an essential resource for ensuring strong economic growth in the state. The Career Technical Education Pathways Initiative (the Initiative) became law in 2005 with Senate Bills 70 and 1133 and provided more than $380 million over eight years to improve career technical education…

Defining a Progress Metric for CERT RMM Improvement

Science.gov (United States)

2017-09-14

REV-03.18.2016.0 Defining a Progress Metric for CERT-RMM Improvement Gregory Crabb Nader Mehravari David Tobar September 2017 TECHNICAL ...fendable resource allocation decisions. Technical metrics measure aspects of controls implemented through technology (systems, soft- ware, hardware...implementation metric would be the percentage of users who have received anti-phishing training . • Effectiveness/efficiency metrics measure whether

Introducing errors in progress ratios determined from experience curves

NARCIS (Netherlands)

van Sark, W.G.J.H.M.

2008-01-01

Progress ratios (PRs) derived from historical data in experience curves are used for forecasting development of many technologies as a means to model endogenous technical change in for instance climate–economy models. These forecasts are highly sensitive to uncertainties in the progress ratio. As a

The Basalt Waste Isolation Project technical program evaluation process: A criteria-based method

International Nuclear Information System (INIS)

Babad, H.; Evans, C.; Wolfe, B.A.

1982-01-01

The need to objectively evaluate the progress being made by the Basalt Waste Isolation Project (BWIP) toward establishing the feasibility of siting a nuclear waste repository in basalt (NWRB) mandates a process for evaluating the technical work of the project. To assist BWIP management in the evaluation process, the Systems Department staff has developed a BWIP Technical Program Evaluation Process (TPEP). The basic process relates progress on project technical work to the BWIP Functional and System Performance Criteria as defined in National Waste Terminal Storage (NWTS) Criteria Documents. The benefits of the TPEP to BWIP and future plans for TPEP are discussed. During fiscal year (FY) 1982, TPEP will be further formalized and further applied to the review of BWIP technical activities

Feed-in tariffs versus quotas: how to promote renewable s and stimulate technical progress for cost decrease?

International Nuclear Information System (INIS)

Menanteau, Ph.; Finon, D.; Lamy, M.L.

2002-01-01

Incentive schemes for the development of renewable energy sources may focus on quantities (defining national targets and setting up bidding systems, or quota systems providing for green certificate trading), or they may focus on prices (feed-in tariffs). Whatever the system chosen, the role of the public authorities is quite specific: to stimulate technical progress and speed up the technological learning processes so that ultimately renewable energy technologies will be able to compete with conventional technologies, once the environmental costs have been internalized. A comparison of instruments must thus take into account the characteristics of the innovation process and adoption conditions (uncertainties regarding cost curves, learning effects) which means also looking at dynamic efficiency criteria. The paper concludes that a system of feed-in tariffs is more efficient than a bidding system, but highlights the theoretical interest of green certificate trading which must be confirmed through practice, given the influence of market structures and rules on the performance of this type of approach. (author)

Modification of the technical properties of Lactobacillus johnsonii NCC 533 by supplementing the growth medium with unsaturated fatty acids.

Science.gov (United States)

Muller, J A; Ross, R P; Sybesma, W F H; Fitzgerald, G F; Stanton, C

2011-10-01

The aim of this study was to investigate the influence of supplementing growth medium with unsaturated fatty acids on the technical properties of the probiotic strain Lactobacillus johnsonii NCC 533, such as heat and acid tolerance, and inhibition of Salmonella enterica serovar Typhimurium infection. Our results showed that the membrane composition and morphology of L. johnsonii NCC 533 were significantly changed by supplementing a minimal Lactobacillus medium with oleic, linoleic, and linolenic acids. The ratio of saturated to unsaturated plus cyclic fatty acids in the bacterial membrane decreased by almost 2-fold when minimal medium was supplemented with unsaturated fatty acids (10 μg/ml). The subsequent acid and heat tolerance of L. johnsonii decreased by 6- and 20-fold when the strain was grown in the presence of linoleic and linolenic acids, respectively, compared with growth in oleic acid (all at 10 μg/ml). Following acid exposure, significantly higher (P acid content was detected in the membrane when growth medium was supplemented with linoleic or linolenic acid, indicating that saturation of the membrane fatty acids occurred during acid stress. Cell integrity was determined in real time during stressed conditions using a fluorescent viability kit in combination with flow cytometric analysis. Following heat shock (at 62.5°C for 5 min), L. johnsonii was unable to form colonies; however, 60% of the bacteria showed no cell integrity loss, which could indicate that the elevated heat inactivated vital processes within the cell, rendering it incapable of replication. Furthermore, L. johnsonii grown in fatty acid-enriched minimal medium had different adhesion properties and caused a 2-fold decrease in S. enterica serovar Typhimurium UK1-lux invasion of HT-29 epithelial cells compared with bacteria grown in minimal medium alone. This could be related to changes in the hydrophobicity and fluidity of the membrane. Our study shows that technical properties

Dendrimer-Based Selective Proteostasis-Inhibition Strategy to Control NSCLC Growth and Progression.

Directory of Open Access Journals (Sweden)

Kyla Walworth

-DDN. Moreover, we confirmed by clonogenic-assay that DDNDBeQ treatment significantly (p<0.001 inhibits H1299 colony-formation as compared to control/DDN. Overall, encapsulation of potent VCP-inhibitor DBeQ into a dendrimer allows selective VCP-mediated proteostasis-inhibition for controlling NSCLC-tumor growth and progression to allow tumor-targeted sustained drug delivery.

Sources of technical assistance

International Nuclear Information System (INIS)

Laue, H.J.

1977-01-01

This paper shows examples of technical assistance programmes within bilateral cooperation agreements between the Federal Republic of Germany and a number of developing countries of very different characteristics and summarizes the possibilities of technical assistance granted by international organizations, such as IAEA, UNDP, etc. A basic requirement for a successful transfer of technology is a high knowledge level of the indigenous scientists and engineers. Therefore, programmes for training and education and for information exchange are presented. Based on these, the means and methods of planning, performance and quality assurance are explained by practical examples and are related to the progress achieved in the use of nuclear energy and in establishing a national industry in the developing countries. (orig.) [de

Geothermal progress monitor. Progress report No. 3, March-April 1980

Energy Technology Data Exchange (ETDEWEB)

1980-01-01

Progress is reviewed in the following areas: electric uses; direct heat uses; drilling activities; exploration; leases; outreach and technical assistance; feasibility studies and application demonstrations; geothermal loan guarantee program; general activities; R and D activities; legal, institutional, and regulatory activities; environmental activities; and state, local, and private sector activities. Also included are a list of reports and publications and a directory of individuals in the geothermal community. (MHR)

Voluntary medical male circumcision scale-up in Nyanza, Kenya: evaluating technical efficiency and productivity of service delivery.

Science.gov (United States)

Omondi Aduda, Dickens S; Ouma, Collins; Onyango, Rosebella; Onyango, Mathews; Bertrand, Jane

2015-01-01

Voluntary medical male circumcision (VMMC) service delivery is complex and resource-intensive. In Kenya's context there is still paucity of information on resource use vis-à-vis outputs as programs scale up. Knowledge of technical efficiency, productivity and potential sources of constraints is desirable to improve decision-making. To evaluate technical efficiency and productivity of VMMC service delivery in Nyanza in 2011/2012 using data envelopment analysis. Comparative process evaluation of facilities providing VMMC in Nyanza in 2011/2012 using output orientated data envelopment analysis. Twenty one facilities were evaluated. Only 1 of 7 variables considered (total elapsed operation time) significantly improved from 32.8 minutes (SD 8.8) in 2011 to 30 minutes (SD 6.6) in 2012 (95%CI = 0.0350-5.2488; p = 0.047). Mean scale technical efficiency significantly improved from 91% (SD 19.8) in 2011 to 99% (SD 4.0) in 2012 particularly among outreach compared to fixed service delivery facilities (CI -31.47959-4.698508; p = 0.005). Increase in mean VRS technical efficiency from 84% (SD 25.3) in 2011 and 89% (SD 25.1) in 2012 was not statistically significant. Benchmark facilities were #119 and #125 in 2011 and #103 in 2012. Malmquist Productivity Index (MPI) at fixed facilities declined by 2.5% but gained by 4.9% at outreach ones by 2012. Total factor productivity improved by 83% (p = 0.032) in 2012, largely due to progress in technological efficiency by 79% (p = 0.008). Significant improvement in scale technical efficiency among outreach facilities in 2012 was attributable to accelerated activities. However, ongoing pure technical inefficiency requires concerted attention. Technological progress was the key driver of service productivity growth in Nyanza. Incorporating service-quality dimensions and using stepwise-multiple criteria in performance evaluation enhances comprehensiveness and validity. These findings highlight site-level resource use and sources of

Voluntary Medical Male Circumcision Scale-Up in Nyanza, Kenya: Evaluating Technical Efficiency and Productivity of Service Delivery

Science.gov (United States)

Omondi Aduda, Dickens S.; Ouma, Collins; Onyango, Rosebella; Onyango, Mathews; Bertrand, Jane

2015-01-01

Background Voluntary medical male circumcision (VMMC) service delivery is complex and resource-intensive. In Kenya’s context there is still paucity of information on resource use vis-à-vis outputs as programs scale up. Knowledge of technical efficiency, productivity and potential sources of constraints is desirable to improve decision-making. Objective To evaluate technical efficiency and productivity of VMMC service delivery in Nyanza in 2011/2012 using data envelopment analysis. Design Comparative process evaluation of facilities providing VMMC in Nyanza in 2011/2012 using output orientated data envelopment analysis. Results Twenty one facilities were evaluated. Only 1 of 7 variables considered (total elapsed operation time) significantly improved from 32.8 minutes (SD 8.8) in 2011 to 30 minutes (SD 6.6) in 2012 (95%CI = 0.0350–5.2488; p = 0.047). Mean scale technical efficiency significantly improved from 91% (SD 19.8) in 2011 to 99% (SD 4.0) in 2012 particularly among outreach compared to fixed service delivery facilities (CI -31.47959–4.698508; p = 0.005). Increase in mean VRS technical efficiency from 84% (SD 25.3) in 2011 and 89% (SD 25.1) in 2012 was not statistically significant. Benchmark facilities were #119 and #125 in 2011 and #103 in 2012. Malmquist Productivity Index (MPI) at fixed facilities declined by 2.5% but gained by 4.9% at outreach ones by 2012. Total factor productivity improved by 83% (p = 0.032) in 2012, largely due to progress in technological efficiency by 79% (p = 0.008). Conclusions Significant improvement in scale technical efficiency among outreach facilities in 2012 was attributable to accelerated activities. However, ongoing pure technical inefficiency requires concerted attention. Technological progress was the key driver of service productivity growth in Nyanza. Incorporating service-quality dimensions and using stepwise-multiple criteria in performance evaluation enhances comprehensiveness and validity. These findings

EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth

Directory of Open Access Journals (Sweden)

Naiara Perurena

2017-01-01

Full Text Available Abstract Background Activated protein C/endothelial protein C receptor (APC/EPCR axis is physiologically involved in anticoagulant and cytoprotective activities in endothelial cells. Emerging evidence indicates that EPCR also plays a role in breast stemness and human tumorigenesis. Yet, its contribution to breast cancer progression and metastasis has not been elucidated. Methods Transcriptomic status of EPCR was examined in a cohort of 286 breast cancer patients. Cell growth kinetics was evaluated in control and EPCR and SPARC/osteonectin, Cwcv, and kazal-like domains proteoglycan (SPOCK1/testican 1 silenced breast cancer cells in 2D, 3D, and in co-culture conditions. Orthotopic tumor growth and lung and osseous metastases were evaluated in several human and murine xenograft breast cancer models. Tumor-stroma interactions were further studied in vivo by immunohistochemistry and flow cytometry. An EPCR-induced gene signature was identified by microarray analysis. Results Analysis of a cohort of breast cancer patients revealed an association of high EPCR levels with adverse clinical outcome. Interestingly, EPCR knockdown did not affect cell growth kinetics in 2D but significantly reduced cell growth in 3D cultures. Using several human and murine xenograft breast cancer models, we showed that EPCR silencing reduced primary tumor growth and secondary outgrowths at metastatic sites, including the skeleton and the lungs. Interestingly, these effects were independent of APC ligand stimulation in vitro and in vivo. Transcriptomic analysis of EPCR-silenced tumors unveiled an effect mediated by matricellular secreted proteoglycan SPOCK1/testican 1. Interestingly, SPOCK1 silencing suppressed in vitro 3D growth. Moreover, SPOCK1 ablation severely decreased orthotopic tumor growth and reduced bone metastatic osteolytic tumors. High SPOCK1 levels were also associated with poor clinical outcome in a subset breast cancer patients. Our results suggest that EPCR

Technical change and total factor productivity growth: the case of Chinese provinces

OpenAIRE

Heshmati, Almas; Kumbhakar, Subal C.

2010-01-01

In the literature technical change is mostly assumed to be exogenous and specified as a function of time. However, some exogenous external factors other than time can also affect technical change. In this paper we model technical change via time trend (purely external non-economic) as well as other exogenous (external economic) factors (technology shifters). We define technology index based on the external economic factors which are indicators of ‘technology’. Thus our definition of productio...

River Protection Project waste feed delivery program technical performance measurement assessment plan

International Nuclear Information System (INIS)

O'TOOLE, S.M.

1999-01-01

This plan establishes a formal technical performance-monitoring program. Technical performance is assessed by establishing requirements based performance goals at the beginning of a program and routinely evaluating progress in meeting these goals at predetermined milestones throughout the project life cycle

Salicylic acid antagonizes abscisic acid inhibition of shoot growth and cell cycle progression in rice

Science.gov (United States)

Meguro, Ayano; Sato, Yutaka

2014-04-01

We analysed effects of abscisic acid (ABA, a negative regulatory hormone), alone and in combination with positive or neutral hormones, including salicylic acid (SA), on rice growth and expression of cell cycle-related genes. ABA significantly inhibited shoot growth and induced expression of OsKRP4, OsKRP5, and OsKRP6. A yeast two-hybrid assay showed that OsKRP4, OsKRP5, and OsKRP6 interacted with OsCDKA;1 and/or OsCDKA;2. When SA was simultaneously supplied with ABA, the antagonistic effect of SA completely blocked ABA inhibition. SA also blocked ABA inhibition of DNA replication and thymidine incorporation in the shoot apical meristem. These results suggest that ABA arrests cell cycle progression by inducing expression of OsKRP4, OsKRP5, and OsKRP6, which inhibit the G1/S transition, and that SA antagonizes ABA by blocking expression of OsKRP genes.

Integral Fast Reactor Program annual progress report, FY 1994

International Nuclear Information System (INIS)

Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, J.J.

1994-12-01

This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1994. Technical accomplishments are presented in the following areas of the IFR technology development activities: metal fuel performance; pyroprocess development; safety experiments and analyses; core design development; fuel cycle demonstration; and LMR technology R ampersand D

Progress in molecular precursors for electronic materials

Energy Technology Data Exchange (ETDEWEB)

Buhro, W.E. [Washington Univ., St. Louis, MO (United States)

1996-09-01

Molecular-precursor chemistry provides an essential underpinning to all electronic-materials technologies, including photovoltaics and related areas of direct interest to the DOE. Materials synthesis and processing is a rapidly developing field in which advances in molecular precursors are playing a major role. This article surveys selected recent research examples that define the exciting current directions in molecular-precursor science. These directions include growth of increasingly complex structures and stoichiometries, surface-selective growth, kinetic growth of metastable materials, growth of size-controlled quantum dots and quantum-dot arrays, and growth at progressively lower temperatures. Continued progress in molecular-precursor chemistry will afford precise control over the crystal structures, nanostructures, and microstructures of electronic materials.

Geothermal direct-heat utilization assistance. Quarterly project progress report, April--June 1993

Energy Technology Data Exchange (ETDEWEB)

Lienau, P.

1993-06-01

Technical assistance was provided to 60 requests from 19 states. R&D progress is reported on: evaluation of lineshaft turbine pump problems, geothermal district heating marketing strategy, and greenhouse peaking analysis. Two presentations and one tour were conducted, and three technical papers were prepared. The Geothermal Progress Monitor reported: USGS Forum on Mineral Resources, Renewable Energy Tax Credits Not Working as Congress Intended, Geothermal Industry Tells House Panel, Newberry Pilot Project, and Low-Temperature Geothermal Resources in Nevada.

South Africa's greenhouse gas emissions under business-as-usual: The technical basis of 'Growth without Constraints' in the Long-Term Mitigation Scenarios

International Nuclear Information System (INIS)

Winkler, Harald; Hughes, Alison; Marquard, Andrew; Haw, Mary; Merven, Bruno

2011-01-01

This article describes the methodology for projecting business-as-usual GHG trajectory developed in technical work for South Africa's Long-Term Mitigation Scenarios (LTMSs), in particular the 'Growth without Constraints' (GWCs) scenario. Technically rigorous projections are important as developing countries define their commitment to act on mitigation relative to business-as-usual (BAU). The key drivers for the GWC scenario include GDP (both growth rate and composition), population, discount rate and technological change. GDP emerged as an important driver in the research for LTMS and further analysis. If South Africa's economy grows without constraints over the next few decades, GHG emissions will continue to escalate, multiplying more than four-fold by mid-century. There is little gain in energy efficiency, and emissions continue to be dominated by energy use and supply, the latter remaining coal-based in GWC. We analyse the projections (not predictions) in relation to various measures. The LTMS GWC scenario is compared to other projections, nationally and internationally. A broadly comparable projection is being used at national level, for electricity planning. When compared to projections from international models, we find that the assumptions about GDP growth rates are a key factor, and suggest that comparisons of global data-sets against national analyses is important. - Highlights: → Specifies business-as-usual GHG trajectory for South Africa's Long-Term Mitigation Scenarios. → Provides details on methodology, drivers of emissions and key parameters. → In a scenario of Growth without Constraints, emissions would quadruple by 2050. → Analysis of resulting emission projection, not a prediction. → Compares projections from other national and international models.

Technical writing in the radiologic technology curriculum.

Science.gov (United States)

Bell, R

1979-01-01

Although courses in technical writing are no longer suggested in the Curriculum Guide for Programs in Radiologic Technology, the writer believes that writing is essential to the growth of the profession and development of the professional. Emphasis is placed on some of the benefits that accrue to students who are exposed to technical writing as part of their technology curriculum.

Growth, institutions and power groups. The forgotten effects in Sinaloa, 1994-2014

Directory of Open Access Journals (Sweden)

Ezequiel Avilés Ochoa

2018-01-01

Full Text Available Through a non-numerical model, this research identifies the relations of causality revealed by omissions of the power groups that are in charge of political and economic institutions in Sinaloa, and which account for the weak local economic growth. This contribution lies in the use of a methodology that evaluates economic performance based on the subjective assessment of experts’ thinking, who are members of the power elite. For this purpose, postulates of the fuzzy subset theory and the forgotten effects model are introduced. The results suggest that the causes of technological backwardness are a fragile democracy and a weak citizen participation, which reduce growth potential by accumulating degrees of omission. Deficient investment in human capital, technology and research and development leads to insufficient technical progress, educational backwardness, technological stagnation and crime.

Geothermal direct-heat utilization assistance. Quarterly progress report, April--June 1993

Energy Technology Data Exchange (ETDEWEB)

1993-08-01

Progress is reported on the following R&D activities: evaluation of lineshaft turbine pump problems, geothermal district heating marketing strategy, and greenhouse peaking analysis. Other activities are reported on technical assistance, technology transfer, and the geothermal progress monitor.

Integral Fast Reactor Program. Annual progress report, FY 1992

Energy Technology Data Exchange (ETDEWEB)

Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, M.J.

1993-06-01

This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1992. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R&D.

Scientific Progress in Strategic Management

DEFF Research Database (Denmark)

Foss, Nicolai Juul

Does the RBV represent a case of scientific progress? And has it emerged as the dominant approach to the analysis of competitive advantage for this reason? Conventional criteria for scientific progress, notably those of the growth of knowledge literature, are not particularly helpful for understa...

Gatlinburg conference: barometer of progress in analytical chemistry

International Nuclear Information System (INIS)

Shults, W.D.

1981-01-01

Much progress has been made in the field of analytical chemistry over the past twenty-five years. The AEC-ERDA-DOE family of laboratories contributed greatly to this progress. It is not surprising then to find a close correlation between program content of past Gatlinburg conferences and developments in analytical methodology. These conferences have proved to be a barometer of technical status

Do the ban on use of anti-microbial growth promoter impact on technical change and the efficiency of slaughter-pig production

DEFF Research Database (Denmark)

Lawson, Lartey; Otto, Lars; Jensen, Peter Vig

2005-01-01

infections, and in effect stimu-lated the utilization of feedstuff and reduced the mortality rate. However, fears for increas-ing bacteria resistance with subsequent health hazards for humans and livestock has lead to societal debates about the pros and cons of its use in livestock production. Antibiotic......This study aims at investigating the effects of the ban on the use of anti-microbial growth promoters in the production of “Finishing Pigs” for slaughter. We investigate if the ban on the use of anti-microbial growth promoters has for specialised pig-producers altered the productivity of inputs......, technical change and the efficiency of production. This paper complements an earlier paper that investigated the impact of the ban on weaned-pig produc-tion. Background: The study is motivated by the fact that antimicrobial growth promoters have been known world wide to protect livestock from bacteria...

Technical reliability of geological disposal for high-level radioactive wastes in Japan. The second progress report. Part 2. Engineering technology for geological disposal

International Nuclear Information System (INIS)

1999-11-01

Based on the Advisory Committee Report on Nuclear Fuel Cycle Backend Policy submitted to the Japanese Government in 1997, JNC documents the progress of research and development program in the form of the second progress report (the first one published in 1992). It summarizes an evaluation of the technical reliability and safety of the deep geological disposal concept for high-level radioactive wastes (HLW) in Japan. The present document, part 2 of the progress report, concerns engineering aspect with reference to Japanese geological disposal plan, according to which the vitrified HLW will be disposed of into a deep, stable rock mass with thick containers and surrounding buffer materials at the depth of several hundred meters. It discusses on multi-barrier systems consisting of a series of engineered and natural barriers that will isolate radioactive nuclides effectively and retard their migrations to the biosphere environment. Performance of repository components, including specifications of containers for vitrified HLW and their overpacks under design as well as buffer material such as Japanese bentonite to be placed in between are described referring also to such possible problems as corrosion arising from the supposed system. It also presents plans and designs for underground disposal facilities, and the presumed management of the underground facilities. (Ohno, S.)

Modification of the Technical Properties of Lactobacillus johnsonii NCC 533 by Supplementing the Growth Medium with Unsaturated Fatty Acids ▿

Science.gov (United States)

Muller, J. A.; Ross, R. P.; Sybesma, W. F. H.; Fitzgerald, G. F.; Stanton, C.

2011-01-01

The aim of this study was to investigate the influence of supplementing growth medium with unsaturated fatty acids on the technical properties of the probiotic strain Lactobacillus johnsonii NCC 533, such as heat and acid tolerance, and inhibition of Salmonella enterica serovar Typhimurium infection. Our results showed that the membrane composition and morphology of L. johnsonii NCC 533 were significantly changed by supplementing a minimal Lactobacillus medium with oleic, linoleic, and linolenic acids. The ratio of saturated to unsaturated plus cyclic fatty acids in the bacterial membrane decreased by almost 2-fold when minimal medium was supplemented with unsaturated fatty acids (10 μg/ml). The subsequent acid and heat tolerance of L. johnsonii decreased by 6- and 20-fold when the strain was grown in the presence of linoleic and linolenic acids, respectively, compared with growth in oleic acid (all at 10 μg/ml). Following acid exposure, significantly higher (P acid content was detected in the membrane when growth medium was supplemented with linoleic or linolenic acid, indicating that saturation of the membrane fatty acids occurred during acid stress. Cell integrity was determined in real time during stressed conditions using a fluorescent viability kit in combination with flow cytometric analysis. Following heat shock (at 62.5°C for 5 min), L. johnsonii was unable to form colonies; however, 60% of the bacteria showed no cell integrity loss, which could indicate that the elevated heat inactivated vital processes within the cell, rendering it incapable of replication. Furthermore, L. johnsonii grown in fatty acid-enriched minimal medium had different adhesion properties and caused a 2-fold decrease in S. enterica serovar Typhimurium UK1-lux invasion of HT-29 epithelial cells compared with bacteria grown in minimal medium alone. This could be related to changes in the hydrophobicity and fluidity of the membrane. Our study shows that technical properties

Technical progress report for the quarter 1 October-31 December 1980

International Nuclear Information System (INIS)

1981-01-01

This report describes the technical accomplishments on the commercial nuclear waste management programs and on the geologic disposal of nuclear wastes. The program is organized into eight tasks: systems, waste package, site, repository, regulatory and institutional, test facilities and excavations, land acquisition, and program management

Development of TRITN : In-house technical information network of Technical Research Institute in The Chugoku Electric Power Co., Inc.

Science.gov (United States)

Ebara, Hisao

With the increase in information amount, progress in information network, diversified technology and change in in-house organization the Technical Research Institute has necessitated to shift the conventional technical database processing by use of personal computers into new system promised for future use. It enables to; provide classification system which meets the needs of the institute; execute distributed processing using workstations; make the low cost processing using commercial softwares; make networks using LAN, WAN personal computer communication, and provide primary materials (text data) on facsimiles using optical disks. Such features are those of technical information database system "TRITN" which is available to any persons and at any time. This paper describes how TRITN was developed and the system outline.

Office of Waste Isolation progress report, October 1976

International Nuclear Information System (INIS)

1977-01-01

Progress of the National Waste Terminal Storage program is reported under: technical projects, facility projects, systems projects, and regulatory affairs. Various media (salt, shales, rocks) for geologic storage are covered

A New Stage in the Development of Secondary Vocational-Technical Schools

Science.gov (United States)

Sedakov, V.

1977-01-01

Recommends that projected growth in the technical-vocational sector of education in the Soviet Union be accompanied by qualitative improvements in areas of political socialization, cultural transmission, and technical development. (Author/DB)

Annual technical progress report: reactor safety, Government fiscal year 1978

International Nuclear Information System (INIS)

1978-01-01

Progress in LMFBR safety studies on accident debris behavior is reported under the following subtask titles: high-temperature-concentration aerosols, large-scale molten fuel tests, sodium release tests, and risk analysis

Recent progress in sodium technology

Energy Technology Data Exchange (ETDEWEB)

Hallett, W. J.

1963-10-15

Progress over the past year in U. S. laboratories studying some of the materials and engineering problems that must be resolved in bringing the technology of sodium to an economically and technically attractive point is reviewed. The status of sodium cooled power reactors in the U. S. is described. (P.C.H.)

1984-85 ISN progress report

International Nuclear Information System (INIS)

1985-01-01

This progress report ISN 1984-1985 deals with the following subjects: nuclear physics theory, peripheral and intermediate energy physics, characteristics of reaction mechanisms in heavy ion collisions, nuclear structure, fundamental interactions, experimental methods and new instrumentation, some interdisciplinary research activities and technical activities, the SARA cyclotron and finally, technology transfer and valorisation [fr

Instrumentation of dynamic gas pulse loading system. Technical progress report, first quarter 1992

Energy Technology Data Exchange (ETDEWEB)

Mohaupt, H.

1992-04-14

The overall goal of this work is to further develop and field test a system of stimulating oil and gas wells, which increases the effective radius of the well bore so that more oil can flow into it, by recording pressure during the gas generation phase in real time so that fractures can be induced more predictably in the producing formation. Task 1: Complete the laboratory studies currently underway with the prototype model of the instrumentation currently being studied. Task 2: Perform field tests of the model in the Taft/Bakersfield area, utilizing operations closest to the engineers working on the project, and optimize the unit for various conditions encountered there. Task 3: Perform field test of the model in DGPL jobs which are scheduled in the mid-continent area, and optimize the unit for downhole conditions encountered there. Task 4: Analyze and summarize the results achieved during the complete test series, documenting the steps for usage of downhole instrumentation in the field, and compile data specifying use of the technology by others. Task 5: Prepare final report for DOE, and include also a report on the field tests completed. Describe and estimate the probability of the technology being commercialized and in what time span. The project has made substantial technical progress, though we are running about a month behind schedule. Expenditures are in line with the schedule. Increased widespread interest in the use of DGPL stimulation has kept us very busy. The computer modeling and test instrumentation developed under this program is already being applied to commercial operations.

The BGO collaboration progress report 1990

International Nuclear Information System (INIS)

Anon.

1990-01-01

A large solid angle BGO calorimeter is under contruction for photo-nuclear experiments at intermediate energy facilities. In this note the status progress of the project, the technical steps undertaken in the construction of the apparatus and the goals of this initiative are reviewed

Savannah River Plant, Works Technical Department monthly progress report for March 1956

International Nuclear Information System (INIS)

1956-01-01

This document details activities of the Works Technical Department during the month of March 1956. It covers reactor technology, separations technology, engineering assistance and heavy water technology

Technical progress report for the quarter 1 October-31 December 1980

Energy Technology Data Exchange (ETDEWEB)

1981-01-01

This report describes the technical accomplishments on the commercial nuclear waste management programs and on the geologic disposal of nuclear wastes. The program is organized into eight tasks: systems, waste package, site, repository, regulatory and institutional, test facilities and excavations, land acquisition, and program management. (DLC)

TECHNICAL COORDINATION

CERN Multimedia

Austin Ball

2013-01-01

  Since the last report, much visible progress has been made, as the LS1 programme approaches the halfway point. From early October, technical and safety shift-crew have been present around the clock, allowing detectors to stay switched on overnight, ensuring that safety systems are operational and instructions for non-expert shift-crew are clear. LS1 progress Throughout the summer, whilst the solenoid vacuum tank and YB0 surfaces were accessible, an extensive installation programme took place to prepare for Tracker colder operation and the PLT installation, in 2014, the Phase 1 Pixel Tracker installation, in 2016–’17, and the HCAL Phase 1 upgrade completion, ending in LS2. This included pipework for N2 or dry air to flush the Tracker bulkhead region, many sensors to monitor temperature and dew point in the Tracker and its service channels, heating wires outside the Tracker cooling bundles, supports for the new vacuum-jacketed, concentric, CO2 Pixel cooling lines, the PLT cool...

Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

International Nuclear Information System (INIS)

Till, C.E.; Chang, Y.I.

1993-01-01

The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions

Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

Energy Technology Data Exchange (ETDEWEB)

Till, C.E.; Chang, Y.I.

1993-03-01

The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions.

Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

Energy Technology Data Exchange (ETDEWEB)

Till, C.E.; Chang, Y.I.

1993-01-01

The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions.

Integral Fast Reactor Program annual progress report, FY 1991

International Nuclear Information System (INIS)

1992-06-01

This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1991. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R ampersand D

Integral Fast Reactor Program. Annual progress report, FY 1993

Energy Technology Data Exchange (ETDEWEB)

Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, M.J.

1994-10-01

This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1993. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R and D.

Integral Fast Reactor Program. Annual progress report, FY 1993

International Nuclear Information System (INIS)

Chang, Y.I.; Walters, L.C.; Laidler, J.J.; Pedersen, D.R.; Wade, D.C.; Lineberry, M.J.

1994-10-01

This report summarizes highlights of the technical progress made in the Integral Fast Reactor (IFR) Program in FY 1993. Technical accomplishments are presented in the following areas of the IFR technology development activities: (1) metal fuel performance, (2) pyroprocess development, (3) safety experiments and analyses, (4) core design development, (5) fuel cycle demonstration, and (6) LMR technology R and D

Effective legal protection in the licensing of technical installations

International Nuclear Information System (INIS)

Froehler, L.

1987-01-01

Undeterminate concepts of law shall match the dynamism of technical progress in licensing technical installations (e.g. section 7, para. 2 no. 3 Atomic Energy Act). The administration and the courts have the duty to equalize normative deficits of regulation. Decrees and administrative provisions have an important impact. Administrative courts shall exercise legal protection more efficiently what e.g. can be possible after a shortening of stages of appeal. (CW) [de

Determination of aims military-technical policy of Ukraine

Directory of Open Access Journals (Sweden)

O. F. Salnikova

2014-06-01

Full Text Available In the article the aims of military-technical policy are considered. Determination of aims (tasks of military-technical policy, its maintenance, requirements to it and directions of its further development it must come true by the analysis of different factors of external and internal environment. Among such factors: geopolitical and military-political position of Ukraine and its military doctrine; realized and operating programs of development (reformation of the soldiery forming and them technical rigging; terms of future military operations and progress of their maintenance, forms, methods and characteristic signs of battle actions trend; substantive provisions of art of war; conceptions, theories and doctrines of battle application of the soldiery forming of the different states; resources dedicated by the state on development of military-technical sphere and others like that. The fundamental chart of sequence of forming of public military-technical policy is presented in the article.

Humic substances in performance assessment of nuclear waste disposal: Actinide and iodine migration in the far-field. First technical progress report

International Nuclear Information System (INIS)

Buckau, G.

2003-04-01

The present project is one in a series of research activities supported by the European Commission on the role of humic substances for the long-term safety of nuclear waste disposal. These activities started in the mid eighties within the MIRAGE project (MIgration of RAdionuclides in the GEosphere) with the most recent project being ''Effects of humic substances on the migration of radionuclides: Complexation and transport of actinides (HUMICS)'' (FI4W-CT96-0028). The HUMICS project was conducted within the fourths framework of the European Commissions research program. It started January 1997 and had a duration of three years. The results of the HUMICS project can be found in three open technical progress reports and a final report [1-4]. In analogy with the HUMICS project, the present project makes use of annual technical progress reports where individual results are published as papers in the form of annexes. By this approach, results rapidly become available to interested parties in a compact form before their publication in various scientific journals and conference proceedings. Furthermore, some of the more preliminary and/or detailed results are not likely to appear in scientific journals and proceedings. The present project is conducted within the fifths framework of the European Commissions research program. It started November 2001 and has a duration of three years. The present report covers the first project year, i.e. November 2001 to September 2002. The project is divided into eight different work packages. These are (i) ''Critical assessment of experimental methods'', (ii) ''Generation and characterization of humic substances'', (iii) ''Radionuclide humate interaction data by designed system investigations'', (iv) ''Characterization of radionuclide humate complexes'', (v) ''Natural chemical analogue studies'', (vi) ''Radionuclide transport experiments'', (vii) ''Model development'', and (viii) ''Performance assessment''. Division of work into

Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

International Nuclear Information System (INIS)

Till, C.E.; Chang, Y.I.

1991-01-01

The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions. 10 refs

Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

Energy Technology Data Exchange (ETDEWEB)

Till, C.E.; Chang, Y.I.

1991-01-01

The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions. 10 refs.

Progress and status of the Integral Fast Reactor (IFR) fuel cycle development

International Nuclear Information System (INIS)

Till, C.E.; Chang, Y.I.

1991-01-01

The Integral Fast Reactor (IFR) fuel cycle holds promise for substantial improvements in economics, diversion-resistance, and waste management. This paper discusses technical features of the IFR fuel cycle, its technical progress, the development status, and the future plans and directions. (author)

GT-MHR COMMERCIALIZATION STUDY TECHNICAL PROGRESS AND COST MANAGEMENT REPORT FOR THE PERIOD AUGUST 1 THROUGH AUGUST 31, 2003

International Nuclear Information System (INIS)

Shenoy, A.S.

2003-01-01

OAK A271 GT-MHR COMERCIALiZATION STUDY TECHNICAL PROGRESS AND COST MANAGEMENT REPORT FOR THE PERIOD AUGUST 1 THROUGH AUGUST 31, 2003. In the process of fabricating the MHR-1 irradiation test capsule, Petten has advised that three thermocouples (out of 24) and the Self Powered Neutron detector were damaged during high temperature brazing with the upper capsule lid. Procurement of new TCs and SPN is in process but there will be a delay in the irradiation test of about nine weeks. Startup of the irradiation is now projected to be July or August 2004. In preparation for performing the nuclear design analysis activities required by the advanced fuel studies task, a complete 3-D nuclear design analysis is first being performed of the GT-MHR reference design. This will serve as the baseline for studies of the advanced fuel nuclear design performance

Fundamental studies of separation processes. Technical progress report

International Nuclear Information System (INIS)

Rogers, L.B.

1975-06-01

Studies using high-precision gas chromatography and supercritical fluid chromatography have produced new types of information on liquid crystals and on behavior of substances in the region of the critical temperature, respectively. In addition, the first successful studies of the effects of pressure on cation exchange have been made using aqueous solutions of alkali metal nitrates. In contrast, progress on separations of isotopic species using gas chromatography has been disappointing. In that area, the chief accomplishment has been a determination of the levels of accuracy and precision with which isotopic abundances can be measured using our quadrupole mass spectrometer. (U.S.)

The Michigan high-level radioactive waste program: Final technical progress report

International Nuclear Information System (INIS)

1987-01-01

This report comprises the state of Michigan's final technical report on the location of a proposed high-level radioactive waste disposal site. Included are a list of Michigan's efforts to review the DOE proposal and a detailed report on the application of geographic information systems analysis techniques to the review process

The improvement of near-term CdTe processing and product capabilities and establishment of next-generation CdTe technology. Annual technical progress report, September 1, 1995--August 31, 1996

Energy Technology Data Exchange (ETDEWEB)

Kester, J.; Albright, S. [Golden Photon, Inc., CO (United States)

1997-07-01

The potential of photovoltaics to become a major global business enterprise still lingers outside the limits of industrial capabilities. For the Cadmium Sulfide/Cadmium Telluride (CdS/CdTe) system this potential has continued to focus on improvements in efficiency, stability, and cost reduction. This triad is the primary objective of the present subcontract with NREL entitled {open_quotes}The Improvement of Near-term CdTe Processing and Product Capabilities & Establishment of Next Generation CdTe Technology{close_quotes}. This subcontract represents an intermediate stage of NREL`s plan to assist the growth of the photovoltaic industry in overcoming the scientific and technical barriers to commercialization. This report outlines the progress that has been made during the period of August 1995 through August 1996. The objectives of this subcontract are to improve processing methods, quantify and understand efficiency improvement mechanisms, meet life-testing goals, and address cadmium safety concerns. Task and subtask goals are defined to meet these objectives in specific areas. The approach to fulfilling the subcontract goals is through a balanced plan of process improvement and mechanism identification. These are carried out and continued through monitoring under various long term and accelerated stress conditions. GPI maintains an on-going awareness of all safety related issues, can in particular, those involving cadmium.

Site characterization progress report: Yucca Mountain, Nevada. Progress report number 17, April 1, 1997--September 30, 1997

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-04-01

The US Department of Energy`s (DOE) Office of Civilian Radioactive Waste Management (OCRWM), created with the enactment of the Nuclear Waste Policy Act of 1982 (NWPA), is tasked to accept and dispose of the nation`s high-level radioactive waste and spent nuclear fuel in a deep geologic repository (high-level radioactive waste program). The report summarizes significant site characterization activities during the period from April 1, 1997 through September 30, 1997, in the evaluation of Yucca Mountain as a potential site for the geologic disposal of spent nuclear fuel and high-level radioactive wastes. The progress report also cites technical reports and research products that provide the detailed information on these activities. Chapter 2 outlines technical and regulatory issues that must be addressed by the Project and planned work toward achieving future objectives concerning the viability assessment, the environmental impact statement, the site recommendation, and the license application. Chapter 3 describes technical progress in preclosure radiological safety analysis, postclosure performance assessment, and performance confirmation activities. Chapter 4 describes various aspects of repository and waste package design and construction. It also discusses the Exploration Studies Facility cross drift. Chapter 5 describes site characterization activities, and Chapter 6 contains a complete list of references.

Site characterization progress report: Yucca Mountain, Nevada. Progress report number 17, April 1, 1997 - September 30, 1997

International Nuclear Information System (INIS)

1998-04-01

The US Department of Energy's (DOE) Office of Civilian Radioactive Waste Management (OCRWM), created with the enactment of the Nuclear Waste Policy Act of 1982 (NWPA), is tasked to accept and dispose of the nation's high-level radioactive waste and spent nuclear fuel in a deep geologic repository (high-level radioactive waste program). The report summarizes significant site characterization activities during the period from April 1, 1997 through September 30, 1997, in the evaluation of Yucca Mountain as a potential site for the geologic disposal of spent nuclear fuel and high-level radioactive wastes. The progress report also cites technical reports and research products that provide the detailed information on these activities. Chapter 2 outlines technical and regulatory issues that must be addressed by the Project and planned work toward achieving future objectives concerning the viability assessment, the environmental impact statement, the site recommendation, and the license application. Chapter 3 describes technical progress in preclosure radiological safety analysis, postclosure performance assessment, and performance confirmation activities. Chapter 4 describes various aspects of repository and waste package design and construction. It also discusses the Exploration Studies Facility cross drift. Chapter 5 describes site characterization activities, and Chapter 6 contains a complete list of references

The Role of Insulin-Like Growth Factor 1 in the Progression of Age-Related Hearing Loss

Directory of Open Access Journals (Sweden)

Lourdes Rodríguez-de la Rosa

2017-12-01

Full Text Available Aging is associated with impairment of sensorial functions and with the onset of neurodegenerative diseases. As pari passu circulating insulin-like growth factor 1 (IGF-1 bioavailability progressively decreases, we see a direct correlation with sensory impairment and cognitive performance in older humans. Age-related sensory loss is typically caused by the irreversible death of highly differentiated neurons and sensory receptor cells. Among sensory deficits, age-related hearing loss (ARHL, also named presbycusis, affects one third of the population over 65 years of age and is a major factor in the progression of cognitive problems in the elderly. The genetic and molecular bases of ARHL are largely unknown and only a few genes related to susceptibility to oxidative stress, excitotoxicity, and cell death have been identified. IGF-1 is known to be a neuroprotective agent that maintains cellular metabolism, activates growth, proliferation and differentiation, and limits cell death. Inborn IGF-1 deficiency leads to profound sensorineural hearing loss both in humans and mice. IGF-1 haploinsufficiency has also been shown to correlate with ARHL. There is not much information available on the effect of IGF-1 deficiency on other human sensory systems, but experimental models show a long-term impact on the retina. A secondary action of IGF-1 is the control of oxidative stress and inflammation, thus helping to resolve damage situations, acute or made chronic by aging. Here we will review the primary actions of IGF-1 in the auditory system and the underlying molecular mechanisms.

Significance of technical rules for environmental pollution control

International Nuclear Information System (INIS)

Grefen, K.

1989-01-01

Technical rules for environmental pollution control are very important in times of intensified technical progress and especially in view of the alterations of the legislative basis of the European Market in 1992. In the fields of jurisprudence, science and technology they serve as a decision-making aid for authorities, specialists in plant development and operation and the preparatory stages of international legislation. The topic is explained by the development of guidelines with the VDI-Commission on Air Pollution Prevention. (orig.) [de

TECHNICAL COORDINATION

CERN Multimedia

Austin Ball

Summary of progress since last CMS week. Ten years of construction work have been completed. CMS is closed, in very close to the ideal low luminosity configuration, and performed well in the first tests with LHC beam. Behind this encouraging news is the story of a summer of intense commitment by many teams (from the collaboration and 3 CERN departments) working together, against the clock and despite many minor setbacks, to ensure that the experiment was ready to play a leading role in the excitement of September 10. Following beampipe bakeout and refill with pure neon, a magnificent effort by the ECAL group and the pt 5 technical crew made it possible to install and commission all 4 ECAL endcap Dees before the end of August. In the shadow of this activity, the barrel and forward pixel trackers and part of the beam monitoring were installed within the vac tank. The pt 5 technical teams then succeeded in safely removing the 20t installation tables and their support blocks from beneath the already installed ...

Activity Progress report 1982-1985

International Nuclear Information System (INIS)

1986-01-01

This reports gives a summary of all activities of the Elementary Particle Physics Department at Saclay between the beginning of 1982 and the end of 1985. The experiments in progress or in preparation are presented by subject. The main technical studies and achievements are also described. Finally lists of publications and information concerning Department organization are given [fr

Emerging Trends in the Globalization of Knowledge: The Role of the Technical Report in Aerospace Research and Development

Science.gov (United States)

Pinelli, Thomas E.; Golich, Vicki L.

1997-01-01

Economists, management theorists, business strategists, and governments alike recognize knowledge as the single most important resource in today's global economy. Because of its relationship to technological progress and economic growth, many governments have taken a keen interest in knowledge, specifically its production, transfer, and use. This paper focuses on the technical report as a product for disseminating the results of aerospace research and development (R&D) and its use and importance to aerospace engineers and scientists. The emergence of knowledge as an intellectual asset, its relationship to innovation, and its importance in a global economy provides the context for the paper. The relationships between government and knowledge and between government and innovation are used to placed knowledge within the context of publicly-funded R&D. Data, including the reader preferences of NASA technical reports, are derived from the NASA/DOD Aerospace Knowledge Diffusion Research Project, a ten-year study of knowledge diffusion in the U.S. aerospace industry.

A Simple extension of Dematerialization Theory: Incorporation of Technical Progress and the Rebound Effect

OpenAIRE

Magee, Christopher L.; Devezas, Tessaleno C.

2016-01-01

Dematerialization is the reduction in the quantity of materials needed to produce something useful over time. Dematerialization fundamentally derives from ongoing increases in technical performance but it can be counteracted by demand rebound - increases in usage because of increased value (or decreased cost) that also results from increasing technical performance. A major question then is to what extent technological performance improvement can offset and is offsetting continuously increasin...

Electronic refrigerant leak detector. Quarterly technical progress report

Energy Technology Data Exchange (ETDEWEB)

Talamas, E. Jr.

1998-10-15

The project comprises three main tasks. They are (1) Develop, design, and fabricate sensors, (2) Develop, design, and fabricate test instruments, (3) Testing and data analysis. The milestone includes 17 sub-tasks for the 52-weeks project period, starting on May 1, 1998 and ending on April 30, 1999. As stated in the Application for Federal Assistance, Micronic intended to relocate to a new office by June of 1998. This decision was delayed, since the first partial payment was transferred on August 12, 1998. Micronic plans to relocate this November. A second Provisional Application for a US patent has been filed. Progress made during this period is reported.

Professional Technical Standards in Colleges and Schools of Pharmacy

Science.gov (United States)

Berry, Tricia M.; Chichester, Clinton O.; Sanoski, Cynthia A.; Woodward, Donald A.; Worley, Marcia M.; Early, Johnnie L.

2011-01-01

Objective To determine the prevalence, characteristics, and use of professional technical standards among colleges and schools of pharmacy accredited by the Accreditation Council for Pharmacy Education (ACPE). Methods The Web site of every college and school of pharmacy accredited by ACPE was searched to identify information regarding the availability, content, and use of technical standards and to obtain demographic information. Results Information was obtained from all of the 114 colleges and schools of pharmacy and 67 (59%) had technical standards in place. Common themes for technical standards were: observation; communication; motor; intellectual, conceptual, integrative and quantitative abilities; and behavioral and social attributes. Of those colleges and schools with technical standards, 61 (91%) had standards that addressed all 5 of these themes and 34 (51%) specified that the technical standards were used in their admission, progression, and graduation procedures. Conclusion More than half of the colleges and schools of pharmacy examined in this study have technical standards; however, 41% have yet to develop and implement them. Colleges and schools of pharmacy looking for guidance in technical standards development could use the technical standards themes identified in this study. PMID:21655404

Coal to SNG: Technical progress, modeling and system optimization through exergy analysis

International Nuclear Information System (INIS)

Li, Sheng; Ji, Xiaozhou; Zhang, Xiaosong; Gao, Lin; Jin, Hongguang

2014-01-01

Highlights: • Technical progresses of coal to SNG technologies are reported. • The entire coal to SNG system is modeled. • Coupling between SNG production and power generation is investigated. • Breakthrough points for further energy saving are determined. • System performance is optimized based on the first and second laws of thermodynamics. - Abstract: For both energy security and CO 2 emission reduction, synthetic natural gas (SNG) production from coal is an important path to implement clean coal technologies in China. In this paper, an overview of the progress of coal to SNG technologies, including the development of catalysts, reactor designs, synthesis processes, and systems integration, is provided. The coal to SNG system is modeled, the coupling between SNG production and power generation is investigated, the breakthrough points for further energy savings are determined, and the system performance is optimized based on the first and the second laws of thermodynamics. From the viewpoint of the first law of thermodynamics, the energy conversion efficiency of coal to SNG system can reach 59.8%. To reduce the plant auxiliary power, the breakthrough points are the development of low-energy-consumption oxygen production technology and gas purification technology or seeking new oxidants for coal gasification instead of oxygen. From the viewpoint of the second law of thermodynamics, the major exergy destruction in a coal to SNG system occurs in the coal gasification unit, SNG synthesis unit and the raw syngas cooling process. How to reduce the exergy destruction in these units is the key to energy savings and system performance enhancement. The conversion ratio of the first SNG synthesis reactor and the split ratio of the recycle gas are key factors that determine the performance of both the SNG synthesis process and the whole plant. A “turning point” phenomenon is observed: when the split ratio is higher than 0.90, the exergy destruction of the SNG

Power systems development facility. Quarterly technical progress report, July 1--September 30, 1993

Energy Technology Data Exchange (ETDEWEB)

1993-12-31

This quarterly technical progress report summarizes work completed during the Second Quarter of the Second Budget Period, July 1 through September 30, 1993, under the Department of Energy (DOE) Cooperative Agreement No. DE-FC21-90MC25140 entitled ``Hot Gas Cleanup Test Facility for Gasification and Pressurized Combustion.`` The objective of this project is to evaluate hot gas particle control technologies using coal-derived gas streams. This will entail the design, construction, installation, and use of a flexible test facility which can operate under realistic gasification and combustion conditions. The major particulate control device issues to be addressed include the integration of the particulate control devices into coal utilization systems, on-line cleaning techniques, chemical and thermal degradation of components, fatigue or structural failures, blinding, collection efficiency as a function of particle size, and scaleup of particulate control systems to commercial size. The conceptual design of the facility was extended to include a within scope, phased expansion of the existing Hot Gas Cleanup Test Facility Cooperative Agreement to also address systems integration issues of hot particulate removal in advanced coal-based power generation systems. This expansion included the consideration of the following modules at the test facility in addition to the existing Transport Reactor gas source and Hot Gas Cleanup Units: Carbonizer/Pressurized Circulating Fluidized Bed Gas Source. Hot Gas Cleanup Units to mate to all gas streams; Combustion Gas Turbine; and Fuel Cell and associated gas treatment. This expansion to the Hot Gas Cleanup Test Facility is herein referred to as the Power Systems Development Facility (PSDF). The major emphasis during this reporting period was continuing the detailed design of the facility.

Private sector involvement in the US program of technical assistance to IAEA safeguards

International Nuclear Information System (INIS)

Pepper, S.E.; Epel, L.; Maise, G.; Reisman, A.; Skalyo, J.

1995-01-01

The US Program of Technical Assistance to IAEA Safeguards (POTAS) relies on technical expertise found in the U. S private and public sectors. Since 1993, the international Safeguards Project Office (ISPO) has sought to increase the role of the private sector in POTAS. ISPO maintains and continues to develop a database of US companies interested in providing technical expertise to the IAEA. This database is used by ISPO to find appropriate contractors to respond to IAEA requests for technical assistance when the assistance can be provided by the private sector. The private sector is currently providing support in the development of equipment, training, and procedure preparation. POTAS also supports the work of private consultants. This paper discusses ISPO's efforts to identify suitable vendors and discusses conditions that hinder more substantial involvement by the private sector. In addition, the paper will discuss selected projects that are currently in progress and identify common problems that impede the progress and success of tasks performed by the private sector

Progress of the HTR-10 project

International Nuclear Information System (INIS)

Zhong, D.; Xu, Y.

1996-01-01

This paper briefly introduces the main technical features and the design specifications of the HTR-10. Present status and main progress of the license applications, the design and manufacture of the main components and the engineering experiments as well as the construction of the HTR-10 are summarized. (author). 3 tabs

Tanks Focus Area FY98 midyear technical review

Energy Technology Data Exchange (ETDEWEB)

Schlahta, S.N.; Brouns, T.M.

1998-06-01

The Tanks Focus Area (TFA) serves as the DOE`s Office of Environmental Management`s national technology and solution development program for radioactive waste tank remediation. Its technical scope covers the major functions that comprise a complete tank remediation system: waste retrieval, waste pretreatment, waste immobilization, tank closure, and characterization of both the waste and tank with safety integrated into all the functions. In total, 17 technologies and technical solutions were selected for review. The purpose of each review was to understand the state of development of each technology selected for review and to identify issues to be resolved before the technology or technical solution progressed to the next level of maturity. The reviewers provided detailed technical and programmatic recommendations and comments. The disposition of these recommendations and comments and their impact on the program is documented in this report.

Tanks Focus Area FY98 midyear technical review

International Nuclear Information System (INIS)

Schlahta, S.N.; Brouns, T.M.

1998-06-01

The Tanks Focus Area (TFA) serves as the DOE's Office of Environmental Management's national technology and solution development program for radioactive waste tank remediation. Its technical scope covers the major functions that comprise a complete tank remediation system: waste retrieval, waste pretreatment, waste immobilization, tank closure, and characterization of both the waste and tank with safety integrated into all the functions. In total, 17 technologies and technical solutions were selected for review. The purpose of each review was to understand the state of development of each technology selected for review and to identify issues to be resolved before the technology or technical solution progressed to the next level of maturity. The reviewers provided detailed technical and programmatic recommendations and comments. The disposition of these recommendations and comments and their impact on the program is documented in this report

Whole Body Vibration Retards Progression of Atherosclerosis via Insulin-Like Growth Factor 1 in Apolipoprotein E-Deficient Mice.

Science.gov (United States)

Wu, He; Zhang, Yibo; Yang, Xuan; Li, Xian; Shao, Zhenya; Zhou, Zipeng; Li, Yuanlong; Pan, Shuwen; Liu, Chang

2018-01-01

Whole body vibration (WBV) has a marked impact on lipid metabolism and the endocrine system, which is related to the progression of atherosclerosis (AS). To investigate the effects of WBV, we measured the atherosclerotic plaque area of apolipoprotein E-knockout (ApoE -/- ) AS mice, which were trained by WBV (15 Hz, 30 min) for 12 weeks. Simultaneously, serum levels of lipids, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 1 receptor (IGF-1R), interleukin 6 (IL-6), and the mRNA and protein levels of the same in the aorta were compared between the control and WBV groups. The results indicated that WBV significantly reduced the atherosclerotic plaque area with lower very low-density lipoprotein (VLDL) and oxidized low-density lipoprotein (ox-LDL) in the blood. Moreover, the levels of IGF-1 in serum and expression of IL-6, IGF-1R, and p-IGF-1R protein in the mice aorta decreased significantly in the WBV group. In addition, we found that serum IGF-1 in mice increased to the highest concentration in 30 min after WBV for 10, 30, 60, and 120 minutes. These results suggested that appropriate WBV may delay the progression of AS, which was associated with acutely elevated serum IGF-1 and lower levels of IGF-1 and IL-6 in the aorta for long-term treatment.

Chemistry of gaseous lower-valent actinide halides. Technical progress report

International Nuclear Information System (INIS)

Hildenbrand, D.L.

1984-01-01

Objective is to provide thermochemical data for key actinide halide and oxyhalide systems. Progress is reported on bond dissociation energies of gaseous ThCl 4 , ThCl 3 , ThCl 2 , and ThCl; bond dissociation energies of ruthenium fluorides; and mass spectroscopy of UF 6

Career Technical Education Pathways Initiative

Science.gov (United States)

California Community Colleges, Chancellor's Office, 2013

2013-01-01

California's education system--the largest in the United States--is an essential resource for ensuring strong economic growth in the state. The Career Technical Education Pathways Initiative (referred to as the Initiative in this report), which became law in 2005, brings together community colleges, K-12 school districts, employers, organized…

Jet Joint Undertaking. Progress report 1990

International Nuclear Information System (INIS)

1991-03-01

This JET Progress Reports provides an overview summary and puts into context the scientific and technical advances made on JET during 1990. In addition, the Report is supplemented by appendices of contributions (in preprint form) of the more important JET articles published during the year, which set out the details of JET activities

Geothermal Progress Monitor Report No. 2, January/February 1980

Energy Technology Data Exchange (ETDEWEB)

1980-01-01

Progress is reviewed in the following aspects of the program: electrical uses; direct-heat uses; leases; outreach and technical assistance; general activities; legal, institutional, and regulatory activities; and reports and publications. (MHR)

Technical and tactical soccer players' performance in conceptual small-sided games

Directory of Open Access Journals (Sweden)

Cristian Javier Ramirez Lizana

2015-09-01

Full Text Available AbstractConceptual small-sided games (CSSGs may be interesting as a methodology for training soccer players given its connection to the unpredictability that is inherent to soccer. Our aim was investigate, through videogrammetry, if the technical and tactical principles promoted through the adoption of distinct rules from two distinct CSSGs (maintaining ball possession; and progression to the target would actually be achieved. The study included 24 athletes assigned to 6-player teams. Our data showed that the CSSGs' organising principles create situations with differing levels of difficulty that obey the propositions of maintaining ball possession and progression to the target, i.e., CSSGs permit systematic training on technical and tactical components in order to emphasize the concepts adopted in this study in games context. Our data credit the CSSGs for teaching technical and tactical lessons that, when coupled with adequate physical conditioning, can facilitate a player's capacity to merge thoughts and events in different situations.

Quarterly technical progress report, February 1, 1996--April 30, 1996

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-05-28

This report from the Amarillo National REsource Center for PLutonium provides research highlights and provides information regarding the public dissemination of information. The center is a a scientific resource for information regarding the issues of the storage, disposition, potential utilization and transport of plutonium, high explosives, and other hazardous materials generated from nuclear weapons dismantlement. The center responds to informational needs and interpretation of technical and scientific data raised by interested parties and advisory groups. Also, research efforts are carried out on remedial action programs and biological/agricultural studies.

High CD49f expression is associated with osteosarcoma tumor progression: a study using patient-derived primary cell cultures.

Science.gov (United States)

Penfornis, Patrice; Cai, David Z; Harris, Michael R; Walker, Ryan; Licini, David; Fernandes, Joseph D A; Orr, Griffin; Koganti, Tejaswi; Hicks, Chindo; Induru, Spandana; Meyer, Mark S; Khokha, Rama; Barr, Jennifer; Pochampally, Radhika R

2014-08-01

Overall prognosis for osteosarcoma (OS) is poor despite aggressive treatment options. Limited access to primary tumors, technical challenges in processing OS tissues, and the lack of well-characterized primary cell cultures has hindered our ability to fully understand the properties of OS tumor initiation and progression. In this study, we have isolated and characterized cell cultures derived from four central high-grade human OS samples. Furthermore, we used the cell cultures to study the role of CD49f in OS progression. Recent studies have implicated CD49f in stemness and multipotency of both cancer stem cells and mesenchymal stem cells. Therefore, we investigated the role of CD49f in osteosarcomagenesis. First, single cell suspensions of tumor biopsies were subcultured and characterized for cell surface marker expression. Next, we characterized the growth and differentiation properties, sensitivity to chemotherapy drugs, and anchorage-independent growth. Xenograft assays showed that cell populations expressing CD49f(hi) /CD90(lo) cell phenotype produced an aggressive tumor. Multiple lines of evidence demonstrated that inhibiting CD49f decreased the tumor-forming ability. Furthermore, the CD49f(hi) /CD90(lo) cell population is generating more aggressive OS tumor growth and indicating this cell surface marker could be a potential candidate for the isolation of an aggressive cell type in OSs. © 2014 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

Technical aspects of high converter reactors

International Nuclear Information System (INIS)

1992-02-01

The meeting provided an opportunity to review and discuss national R and D programs, various technical aspects of and worldwide progress in the implementation of high conversion reactors. The meeting was attended by 66 participants from 18 countries and 2 international organizations. 33 papers were presented. A separate abstract was prepared for each of these papers. Refs, figs, tabs, slides and diagram

Endogenous induced technical change and the costs of Kyoto

International Nuclear Information System (INIS)

Buonanno, Paolo; Carraro, Carlo; Galeotti, M.

2001-09-01

Many predictions and conclusions in the climate change literature have been made and drawn on the basis of theoretical analyses and quantitative models that are either static or that allow for simple forms of changes in technology, often along exogenously given time paths. It is therefore not clear a priori whether those conclusions and policy recipes still hold in the more realistic case of endogenously evolving technologies. In this paper, a quantitative tool with the features of an endogenous growth model is presented, which also accounts for the possibility that technical change can be induced by environmental policy measures. Both the output production technology and the emission-output ratio depend upon the stock of knowledge, which accumulates through R and D activities. R and D is thus an additional policy variable that comes into play along with pollution abatement and capital investment. Two versions of this climate model are studied, one with endogenous technical change but exogenous environmental technical change (i.e. no induced technical change) and the other with both endogenous and induced technical change. Hence, in both models technical change evolves endogenously as far as the production technology is concerned, but endogenous environmental (or induced) technical change is only accounted for in the second version. Finally, a third version of the model also captures technological spillover effects. As an application, the three versions of the model are simulated allowing for trade of pollution permits as specified in the Kyoto Protocol and assessing the implications in terms of cost efficiency, economic growth and R and D efforts of the three different specifications of technical change

Proceedings: Computer Science and Data Systems Technical Symposium, volume 1

Science.gov (United States)

Larsen, Ronald L.; Wallgren, Kenneth

1985-01-01

Progress reports and technical updates of programs being performed by NASA centers are covered. Presentations in viewgraph form are included for topics in three categories: computer science, data systems and space station applications.

The 1988 progress report of the Nuclear Safety and Protection Institut

International Nuclear Information System (INIS)

Anon.

1988-01-01

The 1988 progress report of the Nuclear Safety and Protection Institut (CEA, France). The Institute's fields of action involve: The activities and technical safety of the nuclear power plants, the environmental and human radiation protection which includes technical, health and medical aspects, the nuclear materials compatibility and control and the accident intervention actions. The 1988 Institute activities are characterized by the continuity of the previous technical safety directives, by the improvement of the nuclear risk communication and of the international cooperation [fr

100 Areas technical activities report, engineers - March 1951

Energy Technology Data Exchange (ETDEWEB)

1951-04-01

This is the monthly 100 areas technical activities report from the engineering division for the month of March 1951. It reports on engineering activities related directly to the different production reactors, and gives progress reports on various engineering projects which are in development by the engineering group.

Bioethics for Technical Experts

Science.gov (United States)

Asano, Shigetaka

Along with rapidly expanding applications of life science and technology, technical experts have been implicated more and more often with ethical, social, and legal problems than before. It should be noted that in this background there are scientific and social uncertainty elements which are inevitable during the progress of life science in addition to the historically-established social unreliability to scientists and engineers. In order to solve these problems, therefore, we should establish the social governance with ‘relief’ and ‘reliance’ which enables for both citizens and engineers to share the awareness of the issues, to design social orders and criterions based on hypothetical sense of values for bioethics, to carry out practical use management of each subject carefully, and to improve the sense of values from hypothetical to universal. Concerning these measures, the technical experts can learn many things from the present performance in the medical field.

Technical Progress and Development Directions of Oceanic Spatial Information Datum

Directory of Open Access Journals (Sweden)

BAO Jingyang

2017-10-01

Full Text Available This paper briefly analyzes the basic development and technical situation of oceanic spatial information datum, reviews the main processes of oceanic vertical datum and correlative oceanic tidal study, such as improvement and perfect methods of determining tidal station vertical datum, realizing form of vertical datum controlled by tidal station, effect on maintaining vertical datum by long-term tidal station, oceanic tidal model establishing, and also construction and transformation of tidal datum, and then forecasts the key development directions of oceanic spatial information datum on high-accuracy marine position service, vertical datum and the transferring model refinement and spatial datum application.

Role of ADAMs in cancer formation and progression.

LENUS (Irish Health Repository)

Duffy, Michael J

2012-02-01

The ADAMs (a disintegrin and metalloproteinase) comprise a family of multidomain transmembrane and secreted proteins. One of their best-established roles is the release of biologically important ligands, such as tumor necrosis factor-alpha, epidermal growth factor, transforming growth factor-alpha, and amphiregulin. Because these ligands have been implicated in the formation and progression of tumors, it might be expected that the specific ADAMs involved in their release would also be involved in malignancy. Consistent with this hypothesis, emerging data from model systems suggest that ADAMs, such as ADAM-9, ADAM-12, ADAM-15, and ADAM-17, are causally involved in tumor formation\\/progression. In human cancer, specific ADAMs are up-regulated, with levels generally correlating with parameters of tumor progression and poor outcome. In preclinical models, selective ADAM inhibitors against ADAM-10 and ADAM-17 have been shown to synergize with existing therapies in decreasing tumor growth. The ADAMs are thus a new family of potential targets for the treatment of cancer, especially malignancies that are dependent on human epidermal growth factor receptor ligands or tumor necrosis factor-alpha.

Whole Body Vibration Retards Progression of Atherosclerosis via Insulin-Like Growth Factor 1 in Apolipoprotein E-Deficient Mice

Directory of Open Access Journals (Sweden)

He Wu

2018-01-01

Full Text Available Whole body vibration (WBV has a marked impact on lipid metabolism and the endocrine system, which is related to the progression of atherosclerosis (AS. To investigate the effects of WBV, we measured the atherosclerotic plaque area of apolipoprotein E-knockout (ApoE−/− AS mice, which were trained by WBV (15 Hz, 30 min for 12 weeks. Simultaneously, serum levels of lipids, insulin-like growth factor 1 (IGF-1, insulin-like growth factor 1 receptor (IGF-1R, interleukin 6 (IL-6, and the mRNA and protein levels of the same in the aorta were compared between the control and WBV groups. The results indicated that WBV significantly reduced the atherosclerotic plaque area with lower very low-density lipoprotein (VLDL and oxidized low-density lipoprotein (ox-LDL in the blood. Moreover, the levels of IGF-1 in serum and expression of IL-6, IGF-1R, and p-IGF-1R protein in the mice aorta decreased significantly in the WBV group. In addition, we found that serum IGF-1 in mice increased to the highest concentration in 30 min after WBV for 10, 30, 60, and 120 minutes. These results suggested that appropriate WBV may delay the progression of AS, which was associated with acutely elevated serum IGF-1 and lower levels of IGF-1 and IL-6 in the aorta for long-term treatment.

Canine tracheal epithelial cells are more sensitive than rat tracheal epithelial cells to transforming growth factor beta induced growth inhibition

International Nuclear Information System (INIS)

Hubbs, A.F.; Hahn, F.F.; Kelly, G.; Thomassen, D.G.

1988-01-01

Transforming growth factor beta (TGFβ) markedly inhibited growth of canine tracheal epithelial (CTE) cells. Reduced responsiveness to TGFβ-induced growth inhibition accompanied neoplastic progression of these cells from primary to transformed to neoplastic. This was similar to the relationship between neoplastic progression and increased resistance to TGFβ-induced growth inhibition seen for rat tracheal epithelial (RTE) cells. The canine cells were more sensitive than rat cells to TGFβ-induced growth inhibition at all stages in the neoplastic process. (author)

Bench-scale testing of on-line control of column flotation using a novel analyzer. Third quarterly technical progress report, April 1, 1993--June 30, 1993

Energy Technology Data Exchange (ETDEWEB)

1993-08-24

This document contains the third quarterly technical progress report for PTI`s Bench-Scale Testing Project of a circuit integrating PTI`s KEN-FLOTETM Column Flotation Technology and PTI`s On-Line Quality Monitor and Control System. The twelve-month project involves installation and testing of a 200--300 lb/hr. bench-scale flotation circuit at PETC`s Coal Preparation Process Research Facility (CPPRF) for two bituminous coals (Upper Freeport and Pittsburgh No. 8 Seam Raw Coals). Figure 1 contains the project plan, as well as the approach to completing the major tasks within the twelve-month project schedule. The project is broken down into three phases, which include: Phase I -- Preparation: The preparation phase was performed principally at PTI`s Calumet offices from October through December, 1992. It involved building of the equipment and circuitry, as well as some preliminary design and equipment testing; Phase II -- ET Circuit Installation and Testing: This installation and testing phase of the project was performed at PETC`s CPPRF from January through June, 1993, and was the major focus of the project. It involved testing of the continuous 200--300 lb/hr. circuit; and Phase III -- Project Finalization: The project finalization phase is occurring from July through September, 1993, at PTI`s Calumet offices and involves finalizing analytical work and data evaluation, as well as final project reporting. This Third Quarterly Technical Progress Report principally summarizes the results from the benchscale testing with the second coal (Pittsburgh No. 8 Seam Coal), which occurred in April through June, 1993. It also contains preliminary economic evaluations that will go into the Final Report, as well as the plan for the final reporting task.

Proceedings: Computer Science and Data Systems Technical Symposium, volume 2

Science.gov (United States)

Larsen, Ronald L.; Wallgren, Kenneth

1985-01-01

Progress reports and technical updates of programs being performed by NASA centers are covered. Presentations in viewgraph form, along with abstracts, are included for topics in three catagories: computer science, data systems, and space station applications.

Sensitivity of climate change mitigation estimates to assumptions about technical change

International Nuclear Information System (INIS)

Dowlatabadi, H.

1998-01-01

With greater certainty in anthropogenic influence on observed changes in climate there is increasing pressure for agreements to control emissions of greenhouse gases ([HOUGHTON]). While it is difficult to assess the appropriate level of mitigation, it has been argued that flexibility in meeting emission targets offers significant economic savings. Such flexibility can be exercised in terms of timing of mitigation (i.e. delay) or geographic location of the intervention (e.g. permit trading and Joint-Implementation). Much of this insight is based on standard models of technical change in energy supply and demand. However, standard model formulations rarely consider: (i) a link between the pattern of technical change and policy interventions; (ii) economies of learning; and (iii) technical progress in discovery and recovery of oil and gas. While there is evidence to support the importance of these factors in historic patterns of technical progress, the data necessary to calibrate internally consistent economic models of these phenomena have not been available. In this paper simple representations of endogenous and induced technical change have been used to explore the sensitivity of mitigation cost estimates to how technical change is represented in energy economics models. The scenarios involve control of CO 2 emissions to limit its concentration to no more than 550 ppm(v), starting in the year 2000, and delayed to 2025. This sensitivity analysis has revealed four robust insights: (i) If endogenous technical change is assumed, expected business as usual emissions are higher than otherwise estimated - nevertheless, while 25% greater CO 2 control is required for meeting the CO 2 concentration target, the cost of mitigation is 40% lower; (ii) If technical progress in oil and gas discovery and recovery is assumed, energy use and CO 2 emissions increase by 75% and 65%, respectively above the standard estimates; (iii) If the economies of learning exhibited in various

Autobiographical Writing in the Technical Writing Course

Science.gov (United States)

Gellis, Mark

2011-01-01

Professionals in the workplace are rarely asked to write autobiographical essays. Such essays, however, are an excellent tool for helping students explore their growth as professionals. This article explores the use of such essays in a technical writing class.

Attenuated expression of HRH4 in colorectal carcinomas: a potential influence on tumor growth and progression

International Nuclear Information System (INIS)

Fang, Zhengyu; Wan, Jun; Yao, Wantong; Xiong, Yi; Li, Jiana; Liu, Li; Shi, Lei; Zhang, Wei; Zhang, Chao; Nie, Liping

2011-01-01

Earlier studies have reported the production of histamine in colorectal cancers (CRCs). The effect of histamine is largely determined locally by the histamine receptor expression pattern. Recent evidence suggests that the expression level of histamine receptor H4 (HRH4) is abnormal in colorectal cancer tissues. However, the role of HRH4 in CRC progression and its clinical relevance is not well understood. The aim of this study is to evaluate the clinical and molecular phenotypes of colorectal tumors with abnormal HRH4 expression. Immunoblotting, real-time PCR, immunofluorescence and immunohistochemistry assays were adopted to examine HRH4 expression in case-matched CRC samples (n = 107) and adjacent normal tissues (ANTs). To assess the functions of HRH4 in CRC cells, we established stable HRH4-transfected colorectal cells and examined cell proliferation, colony formation, cell cycle and apoptosis in these cells. The protein levels of HRH4 were reduced in most of the human CRC samples regardless of grade or Dukes classification. mRNA levels of HRH4 were also reduced in both early-stage and advanced CRC samples. In vitro studies showed that HRH4 over-expression caused growth arrest and induced expression of cell cycle proteins in CRC cells upon exposure to histamine through a cAMP -dependent pathway. Furthermore, HRH4 stimulation promoted the 5-Fu-induced cell apoptosis in HRH4-positive colorectal cells. The results from the current study supported previous findings of HRH4 abnormalities in CRCs. Expression levels of HRH4 could influence the histamine-mediated growth regulation in CRC cells. These findings suggested a potential role of abnormal HRH4 expression in the progression of CRCs and provided some new clues for the application of HRH4-specific agonist or antagonist in the molecular therapy of CRCs

Attenuated expression of HRH4 in colorectal carcinomas: a potential influence on tumor growth and progression

Directory of Open Access Journals (Sweden)

Zhang Wei

2011-05-01

Full Text Available Abstract Background Earlier studies have reported the production of histamine in colorectal cancers (CRCs. The effect of histamine is largely determined locally by the histamine receptor expression pattern. Recent evidence suggests that the expression level of histamine receptor H4 (HRH4 is abnormal in colorectal cancer tissues. However, the role of HRH4 in CRC progression and its clinical relevance is not well understood. The aim of this study is to evaluate the clinical and molecular phenotypes of colorectal tumors with abnormal HRH4 expression. Methods Immunoblotting, real-time PCR, immunofluorescence and immunohistochemistry assays were adopted to examine HRH4 expression in case-matched CRC samples (n = 107 and adjacent normal tissues (ANTs. To assess the functions of HRH4 in CRC cells, we established stable HRH4-transfected colorectal cells and examined cell proliferation, colony formation, cell cycle and apoptosis in these cells. Results The protein levels of HRH4 were reduced in most of the human CRC samples regardless of grade or Dukes classification. mRNA levels of HRH4 were also reduced in both early-stage and advanced CRC samples. In vitro studies showed that HRH4 over-expression caused growth arrest and induced expression of cell cycle proteins in CRC cells upon exposure to histamine through a cAMP -dependent pathway. Furthermore, HRH4 stimulation promoted the 5-Fu-induced cell apoptosis in HRH4-positive colorectal cells. Conclusion The results from the current study supported previous findings of HRH4 abnormalities in CRCs. Expression levels of HRH4 could influence the histamine-mediated growth regulation in CRC cells. These findings suggested a potential role of abnormal HRH4 expression in the progression of CRCs and provided some new clues for the application of HRH4-specific agonist or antagonist in the molecular therapy of CRCs.

World progress toward fusion energy

International Nuclear Information System (INIS)

Davies, N.A.

1989-01-01

The author discusses international progress in fusion research during the last three years. Much of the technical progress has been achieved through international collaboration in magnetic fusion research. This progress has stimulated political interest in a multinational effort, aimed at designing and possibly constructing the world's first experimental fusion reactor. This interest was reflected in recent summit-level discussions involving President Mitterand, General Secretary Gorbachev, and President Reagan. Most recently, the European Community (EC), Japan, the United States, and the U.S.S.R. have decided to begin serious preparation for taking the next step toward practical fusion energy. These parties have agreed to begin the design and supporting R and D for an International Thermonuclear Experimental Reactor (ITER) under the auspices of the International Atomic Energy Agency (IAEA). The initiation of this international program to prepare for a fusion test reactor is discussed

Dynamic crack growth in a nonlocal progressively cavitating solid

DEFF Research Database (Denmark)

Needleman, A.; Tvergaard, Viggo

1998-01-01

Dynamic crack growth is analyzed numerically using a nonlocal constitutive formulation for a porous ductile material. The delocalization relates to the void growth and coalescence mechanism and is incorporated in terms of an integral condition on the rate of increase of the void volume fraction....... The material is modeled as elastic-viscoplastic with the thermal softening due to adiabatic heating accounted for. Finite element computations are carried our for edge cracked specimens subject to tensile impact loading. Two values of the material characteristic length and two finite-element discretizations...... are used in most computations. The effect of the material characteristic length on the crack growth behavior and on the mesh sensitivity of the results is considered. For comparison purposes, results are also obtained For the corresponding local constitutive relation. The crack growth resistance is found...

Endogenous induced technical change and the costs of Kyoto

International Nuclear Information System (INIS)

Buonanno, Paolo; Carraro, Carlo; Galeotti, Marzio

2003-01-01

We present a model for climate change policy analysis which accounts for the possibility that technology evolves endogenously and that technical change can be induced by environmental policy measures. Both the output production technology and the emission-output ratio depend upon a stock of knowledge, which accumulates through R and D activities. Two versions of this model are studied, one with endogenous technical change but exogenous environmental technical change and the other with both endogenous and induced technical change. A third version also captures technological spillover effects. As an application, the model is simulated allowing for trade of pollution permits as specified in the Kyoto Protocol and assessing the implications in terms of cost efficiency, economic growth and R and D efforts of the three different specifications of technical change

Fifth technical meeting on quality

International Nuclear Information System (INIS)

Girard, A.

1998-01-01

This article reports on the 5th Technical Meeting on Quality which was held in San Diego on 20-22 October 1997 and which was attended by representatives of the Home and Joint Central Team and of manufacturers currently involved in the Large R and D projects. The meeting made progress towards the finalization of the ITER Quality Manual document for inclusion in the Final Design Report and the definition of the quality necessary for ITER procurement and construction

Environmental Research Division technical progress report: January 1986--October 1987

International Nuclear Information System (INIS)

1988-07-01

Technical process in the various research activities of Argonne National Laboratory's Environmental Research Division is reported for the period 1986-1987. Textual, graphic, and tabular information is used to briefly summarize (in separate chapters) the work of the Division's Atmospheric Physics, Environmental Effects Research, Fundamental Molecular Physics and Chemistry, and Organic Geochemistry and Environmental Instrumentation Programs. Information on professional qualifications, awards, and outstanding professional activities of staff members, as well as lists of publications, oral presentations, special events organized, and participants in educational programs, are provided in appendices at the end of each chapter. Individual projects under each division are processed separately for the data bases

Environmental Research Division technical progress report: January 1986--October 1987

Energy Technology Data Exchange (ETDEWEB)

1988-07-01

Technical process in the various research activities of Argonne National Laboratory's Environmental Research Division is reported for the period 1986-1987. Textual, graphic, and tabular information is used to briefly summarize (in separate chapters) the work of the Division's Atmospheric Physics, Environmental Effects Research, Fundamental Molecular Physics and Chemistry, and Organic Geochemistry and Environmental Instrumentation Programs. Information on professional qualifications, awards, and outstanding professional activities of staff members, as well as lists of publications, oral presentations, special events organized, and participants in educational programs, are provided in appendices at the end of each chapter. Individual projects under each division are processed separately for the data bases.

A new look at the decomposition of agricultural productivity growth incorporating weather effects.

Science.gov (United States)

Njuki, Eric; Bravo-Ureta, Boris E; O'Donnell, Christopher J

2018-01-01

Random fluctuations in temperature and precipitation have substantial impacts on agricultural output. However, the contribution of these changing configurations in weather to total factor productivity (TFP) growth has not been addressed explicitly in econometric analyses. Thus, the key objective of this study is to quantify and to investigate the role of changing weather patterns in explaining yearly fluctuations in TFP. For this purpose, we define TFP to be a measure of total output divided by a measure of total input. We estimate a stochastic production frontier model using U.S. state-level agricultural data incorporating growing season temperature and precipitation, and intra-annual standard deviations of temperature and precipitation for the period 1960-2004. We use the estimated parameters of the model to compute a TFP index that has good axiomatic properties. We then decompose TFP growth in each state into weather effects, technological progress, technical efficiency, and scale-mix efficiency changes. This approach improves our understanding of the role of different components of TFP in agricultural productivity growth. We find that annual TFP growth averaged 1.56% between 1960 and 2004. Moreover, we observe substantial heterogeneity in weather effects across states and over time.

Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma.

Science.gov (United States)

Mazzocca, Antonio; Fransvea, Emilia; Dituri, Francesco; Lupo, Luigi; Antonaci, Salvatore; Giannelli, Gianluigi

2010-02-01

Tumor-stroma interactions in hepatocellular carcinoma (HCC) are of key importance to tumor progression. In this study, we show that HCC invasive cells produce high levels of connective tissue growth factor (CTGF) and generate tumors with a high stromal component in a xenograft model. A transforming growth factor beta (TGF-beta) receptor inhibitor, LY2109761, inhibited the synthesis and release of CTGF, as well as reducing the stromal component of the tumors. In addition, the TGF-beta-dependent down-regulation of CTGF diminished tumor growth, intravasation, and metastatic dissemination of HCC cells by inhibiting cancer-associated fibroblast proliferation. By contrast, noninvasive HCC cells were found to produce low levels of CTGF. Upon TGF-beta1 stimulation, noninvasive HCC cells form tumors with a high stromal content and CTGF expression, which is inhibited by treatment with LY2109761. In addition, the acquired intravasation and metastatic spread of noninvasive HCC cells after TGF-beta1 stimulation was blocked by LY2109761. LY2109761 interrupts the cross-talk between cancer cells and cancer-associated fibroblasts, leading to a significant reduction of HCC growth and dissemination. Interestingly, patients with high CTGF expression had poor prognosis, suggesting that treatment aimed at reducing TGF-beta-dependent CTGF expression may offer clinical benefits. Taken together, our preclinical results indicate that LY2109761 targets the cross-talk between HCC and the stroma and provide a rationale for future clinical trials.

Technical writing versus technical writing

Science.gov (United States)

Dillingham, J. W.

1981-01-01

Two terms, two job categories, 'technical writer' and 'technical author' are discussed in terms of industrial and business requirements and standards. A distinction between 'technical writing' and technical 'writing' is made. The term 'technical editor' is also considered. Problems inherent in the design of programs to prepare and train students for these jobs are discussed. A closer alliance between industry and academia is suggested as a means of preparing students with competent technical communication skills (especially writing and editing skills) and good technical skills.

Establishing a cause and effect relationship for ambient ozone exposure and tree growth in the forest: Progress and an experimental approach

International Nuclear Information System (INIS)

Manning, William J.

2005-01-01

Much has been written about the effects of ambient ozone on tree growth. Cause and effect has been established with seedlings in chambers. Results from multi-year studies with older tree seedlings, in open-top chambers, have been inconclusive, due to chamber effects. Extrapolation of results from chambers to trees in the forest is not possible. Predictive models for forest tree growth reductions caused by ozone have been developed, but not verified. Dendrochronological methods have been used to establish correlations between radial growth reductions in forest trees and ambient ozone exposure. The protective chemical ethylenediurea (EDU) has been used to protect tree seedlings from ozone injury. An experimental approach is advocated here that utilizes forest trees selected for sensitivity and non-sensitivity to ozone, dendrochronological methods, the protective chemical EDU, and monitoring data for ambient ozone, stomatal conductance, soil moisture potential, air temperature, PAR, etc. in long-term investigations to establish cause and effect relationships. - Progress is reviewed and an experimental approach is proposed to demonstrate a cause and effect relationship for ambient ozone and forest tree growth

Inertial fusion research: Annual technical report, 1985

International Nuclear Information System (INIS)

Larsen, J.T.; Terry, N.C.

1986-03-01

This report describes the inertial confinement fusion (ICF) research activities undertaken at KMS Fusion (KMSF) during 1985. It is organized into three main technical sections; the first covers fusion experiments and theoretical physics, the second is devoted to progress in materials development and target fabrication, and the third describes laser technology research. These three individual sections have been cataloged separately

Plasma Vascular Endothelial Growth Factor Concentration and Alveolar Nitric Oxide as Potential Predictors of Disease Progression and Mortality in Idiopathic Pulmonary Fibrosis

Directory of Open Access Journals (Sweden)

Jalpa Kotecha

2016-09-01

Full Text Available Background: Declining lung function signifies disease progression in idiopathic pulmonary fibrosis (IPF. Vascular endothelial growth factor (VEGF concentration is associated with declining lung function in 6 and 12-month studies. Alveolar nitric oxide concentration (CANO is increased in patients with IPF, however its significance is unclear. This study investigated whether baseline plasma VEGF concentration and CANO are associated with disease progression or mortality in IPF. Methods: 27 IPF patients were studied (maximum follow-up 65 months. Baseline plasma VEGF concentration, CANO and pulmonary function tests (PFTs were measured. PFTs were performed the preceding year and subsequent PFTs and data regarding mortality were collected. Disease progression was defined as one of: death, relative decrease of ≥10% in baseline forced vital capacity (FVC % predicted, or relative decrease of ≥15% in baseline single breath diffusion capacity of carbon monoxide (TLCO-SB % predicted. Results: Plasma VEGF concentration was not associated with progression-free survival or mortality. There was a trend towards shorter time to disease progression and death with higher CANO. CANO was significantly higher in patients with previous declining versus stable lung function. Conclusion: The role of VEGF in IPF remains uncertain. It may be of value to further investigate CANO in IPF.

Yucca Mountain Project technical status report (TSR), October 1989--March 1990

International Nuclear Information System (INIS)

1990-01-01

This Yucca Mountain Project Technical Status Report (TSR) on site characterization is the second in a series of reports that will be issued at approximately six-month intervals during site characterization. In addition, progress made toward the initiation and conduct of new site characterization activities is included. For this report, information on the technical progress made by Yucca Mountain Project participating organizations has been compiled covering the period from October 1989, through March 31, 1990. The status report consists of three sections: an introductory section; a section on the status of site characterization, which includes preparatory activities, sites programs, repository design, seals system design, waste package design, and performance assessment; and a reference section, which provides a complete listing of all published documents cited in the text. 59 refs

A Portfolio Analysis Tool for Measuring NASAs Aeronautics Research Progress toward Planned Strategic Outcomes

Science.gov (United States)

Tahmasebi, Farhad; Pearce, Robert

2016-01-01

Description of a tool for portfolio analysis of NASA's Aeronautics research progress toward planned community strategic Outcomes is presented. The strategic planning process for determining the community Outcomes is also briefly described. Stakeholder buy-in, partnership performance, progress of supporting Technical Challenges, and enablement forecast are used as the criteria for evaluating progress toward Outcomes. A few illustrative examples are also presented.

South Africa's greenhouse gas emissions under business-as-usual: The technical basis of 'Growth without Constraints' in the Long-Term Mitigation Scenarios

Energy Technology Data Exchange (ETDEWEB)

Winkler, Harald, E-mail: Harald.WInkler@uct.ac.za [University of Cape Town, Energy Research Centre, Upper Campus, Rondebosch, W Cape 7701 (South Africa); Hughes, Alison; Marquard, Andrew [University of Cape Town, Energy Research Centre, Upper Campus, Rondebosch, W Cape 7701 (South Africa); Haw, Mary [PJCarew Consulting, 103 Hout Street, Cape Town 8001 (South Africa); Merven, Bruno [University of Cape Town, Energy Research Centre, Upper Campus, Rondebosch, W Cape 7701 (South Africa)

2011-10-15

This article describes the methodology for projecting business-as-usual GHG trajectory developed in technical work for South Africa's Long-Term Mitigation Scenarios (LTMSs), in particular the 'Growth without Constraints' (GWCs) scenario. Technically rigorous projections are important as developing countries define their commitment to act on mitigation relative to business-as-usual (BAU). The key drivers for the GWC scenario include GDP (both growth rate and composition), population, discount rate and technological change. GDP emerged as an important driver in the research for LTMS and further analysis. If South Africa's economy grows without constraints over the next few decades, GHG emissions will continue to escalate, multiplying more than four-fold by mid-century. There is little gain in energy efficiency, and emissions continue to be dominated by energy use and supply, the latter remaining coal-based in GWC. We analyse the projections (not predictions) in relation to various measures. The LTMS GWC scenario is compared to other projections, nationally and internationally. A broadly comparable projection is being used at national level, for electricity planning. When compared to projections from international models, we find that the assumptions about GDP growth rates are a key factor, and suggest that comparisons of global data-sets against national analyses is important. - Highlights: > Specifies business-as-usual GHG trajectory for South Africa's Long-Term Mitigation Scenarios. > Provides details on methodology, drivers of emissions and key parameters. > In a scenario of Growth without Constraints, emissions would quadruple by 2050. > Analysis of resulting emission projection, not a prediction. > Compares projections from other national and international models.

Progress of the radioactive waste management at the Dalat Nuclear Research Institute and the role of an IAEA technical co-operation project in this process

International Nuclear Information System (INIS)

Nang, N.T.; Ngoc, O.V.; Nhu Thuy, T.T.; Nghi, D.V.; Thu, N.T.

2002-01-01

At present, the main radioactive waste generator in Vietnam is the Dalat Nuclear Research Institute (DNRI). For safe management of radioactive waste generated from this nuclear center, in 1982 Soviet specialists newly constructed one combined technology system for low level radioactive waste management. The existing system consists of two main parts, a Liquid Radioactive Waste Treatment Station and a Storage/Disposal Facility. The liquid treatment station can in principle meet the needs for this nuclear center but disposal technology and storage/disposal facilities are not good enough both with respect to safety and economy, especially the storage/disposal facility placed in Dalat, the tourist city. In order to help DNRI and Vietnam to solve the radioactive waste management problem, the IAEA Technical Co-operation (TC) project VIE/9/007 was implemented in Vietnam. The facilities and IAEA experts provided under this project gradually help to develop radioactive waste management at DNRI, Vietnam. This paper outlines progress under way in the management of the radioactive waste at the Nuclear Research Institute (NRI), Dalat, Vietnam, and the role of the IAEA Technical Co-operation (TC) project in this process. (author)

Analytical Chemistry Division annual progress report for period ending December 31, 1979

International Nuclear Information System (INIS)

Shults, W.D.; Lyon, W.S.

1980-05-01

The progress is reported in the following sections: analytical methodology, mass and emission spectrometry, technical support, bio-organic analysis, nuclear and radiochemical analysis, and quality assurance

Progress Report. Teilinstitut Nukleare Festkoerperphysik

International Nuclear Information System (INIS)

Kaefer, K.

1978-10-01

This Progress Report of the Teilinstitut Nukleare Festkoerperphysik covers the work done at the Institute during the period from June 1, 1977 to May 31, 1978. The main research areas presently under investigation are underlined by the arrangement of the report: structure and dynamics of solids, electronic structure and magnetism of solids, and the development and investigation of novel materials. Some technical developments important in carrying out this research are included as well. (orig.) [de

Assessing Progress in Mastery of Counseling Communication Skills

NARCIS (Netherlands)

A.J. Kuntze (Jeroen)

2009-01-01

textabstractDuring the last century the attention paid in higher education to the development of professional skills has progressively increased. In the first half of the last century the term ‘skill’ mainly referred to motor or technical actions, for instance driving a car or operating a machine

Technical Assessment of Cryo-Compressed Hydrogen Storage Tank Systems for Automotive Applications

Energy Technology Data Exchange (ETDEWEB)

Ahluwalia, Rajesh [Argonne National Lab. (ANL), Argonne, IL (United States); Hua, T. Q. [Argonne National Lab. (ANL), Argonne, IL (United States); Peng, J. -K. [Argonne National Lab. (ANL), Argonne, IL (United States); Lasher, S. [TIAX LLC, Lexington, MA (United States); McKenney, Kurtis [TIAX LLC, Lexington, MA (United States); Sinha, J. [TIAX LLC, Lexington, MA (United States)

2009-12-01

Technical report describing DOE's second assessment report on a third generation (Gen3) system capable of storing hydrogen at cryogenic temperatures within a pressure vessel on-board a vehicle. The report includes an overview of technical progress to date, including the potential to meet DOE onboard storage targets, as well as independent reviews of system cost and energy analyses of the technology paired with delivery costs.

Consolidated fuel reprocessing program. Progress report, July 1-September 30, 1981

International Nuclear Information System (INIS)

1981-12-01

Technical progress is reported in overview fashion in the following areas: process development, laboratory R and D, engineering research, engineering systems, integrated equipment test facility (IET) operations, and HTGR fuel reprocessing

Technical and economic feasibility of membrane technology. Fourth technical progress report, June 17-September 16, 1980

Energy Technology Data Exchange (ETDEWEB)

Sandre, A.

1980-10-01

Progress is reported on the investigation of the potential application of reverse osmosis, ultrafiltration and electrodialysis to the system of solids concentration in beet sugar process streams. During this period, emphasis was put on running reverse osmosis tests with a new prototype machine to select the most suitable membranes for the concentrating of sugar solutions. An economic analysis of using reverse osmosis in a factory producing 10/sup 6/ gal/day of thin juice is discussed. (DMC)

Pollution externalities in a Schumpeterian growth model

OpenAIRE

Koesler, Simon

2010-01-01

This paper extends a standard Schumpeterian growth model to include an environmental dimension. Thereby, it explicitly links the pollution intensity of economic activity to technological progress. In a second step, it investigates the effect of pollution on economic growth under the assumption that pollution intensities are related to technological progress. Several conclusions emerge from the model. In equilibrium, the economy follows a balanced growth path. The effect of pollution on the ec...

Impact of demographic policy on population growth.

Science.gov (United States)

Podyashchikh, P

1968-01-01

overpopulation is eliminated. This represents the primary difference between the demographic law of socialism and the law of capitalism. In the Soviet Union a gradual decrease of the birthrate and the growth rate of population is evident. The industrialization of the country and collectivization of the peasant farms carried into effect within a short time by the Soviet rule ensured quick progress in economy. The high standard of economic and cultural development achieved in the Soviet Union soon affected the indices of the population's production. The birthrate in the Soviet Union was affected essentially by the causes acting toward its decrease as in the western countries, but under socialist conditions of production these asserted themselves largely in a different way. The experience of the Soviet Union demonstrates that by making use of the scientific and technical knowledge at the command of humankind, industrialization can be realized.

Analytical Chemistry Division annual progress report for period ending December 31, 1979

Energy Technology Data Exchange (ETDEWEB)

Shults, W.D.; Lyon, W.S. (ed.)

1980-05-01

The progress is reported in the following sections: analytical methodology, mass and emission spectrometry, technical support, bio-organic analysis, nuclear and radiochemical analysis, and quality assurance. (DLC)

The present global financial and economic crisis and the oil crises of the 1970s. Opposite turning points in the development of economic growth, energy supply, and the role of nuclear power?

International Nuclear Information System (INIS)

Herrmann, Dieter

2012-01-01

After decades of extensive economic growth, the oil crises in the 1970s enforced the transition to intensive growth in a manner conserving resources, combined with a fundamental turnaround in the development of global energy supply and the role of nuclear power. Meanwhile, the world has changed considerably as a result of population growth, technical progress, and globalization - and it is in the throes of another crisis. The contribution shows, on the basis of empirical indicators, that higher commodity prices halted the period of intense growth already in late 2007. The following global financial and economic crisis can be interpreted plausibly as a return to extensive economic growth worldwide. This is likely to have far-reaching consequences for the future development of global energy supply and the role of nuclear power. (orig.)

JET Joint Undertaking. Progress report 1991 - volume 1

International Nuclear Information System (INIS)

1992-04-01

The ninth JET Progress Report provides an overview summary and puts into context the scientific and technical advances made on JET during 1991. The report contains a brief summary of the background to the project, and describes the basic objectives of JET and the principal design aspects of the machine

The environment and directed technical change: comment

International Nuclear Information System (INIS)

Hourcade, Jean-Charles; Pottier, Antonin; Espagne, Etienne

2011-11-01

This paper discusses the growth model with environmental constraints recently presented in (Acemoglu et al., 2011) which focuses on the redirection of technical change by climate policies with research subsidies and a carbon tax. First, Acemoglu et al.'s model and chosen parameters yield numerical results that do not support the conclusion that ambitious climate policies can be conducted 'without sacrificing (much or any) long-run growth'. Second, they select unrealistic key parameters for carbon sinks and elasticity of substitution. We find that more realistic parameters lead to very different results. Third, the model leads to an unrealistic conclusion when used to analyse endogenous growth, suggesting specification problems. (authors)

Tracking the Progress of English Language Learners

Science.gov (United States)

Murphy, Audrey F.

2009-01-01

Educators need to document progress for English language learners, and the best structures to put into place in order to record their growth. Beginning with the stages of language proficiency, student progress can be tracked through the use of a baseline in all four language strands and the creation of rubrics to monitor performance. Language…

Advanced thermally stable jet fuels: Technical progress report, October 1994--December 1994

Energy Technology Data Exchange (ETDEWEB)

Schobert, H.H.; Eser, S.; Song, C.; Hatcher, P.G.; Boehman, A.; Coleman, M.M.

1995-02-01

There are five tasks within this project on thermally stable coal-based jet fuels. Progress on each of the tasks is described. Task 1, Investigation of the quantitative degradation chemistry of fuels, has 5 subtasks which are described: Literature review on thermal stability of jet fuels; Pyrolytic and catalytic reactions of potential endothermic fuels: cis- and trans-decalin; Use of site specific {sup 13}C-labeling to examine the thermal stressing of 1-phenylhexane: A case study for the determination of reaction kinetics in complex fuel mixtures versus model compound studies; Estimation of critical temperatures of jet fuels; and Surface effects on deposit formation in a flow reactor system. Under Task 2, Investigation of incipient deposition, the subtask reported is Uncertainty analysis on growth and deposition of particles during heating of coal-derived aviation gas turbine fuels; under Task 3, Characterization of solid gums, sediments, and carbonaceous deposits, is subtask, Studies of surface chemistry of PX-21 activated carbon during thermal degradation of jet A-1 fuel and n-dodecane; under Task 4, Coal-based fuel stabilization studies, is subtask, Exploratory screening and development potential of jet fuel thermal stabilizers over 400 C; and under Task 5, Exploratory studies on the direct conversion of coal to high quality jet fuels, are 4 subtasks: Novel approaches to low-severity coal liquefaction and coal/resid co-processing using water and dispersed catalysts; Shape-selective naphthalene hydrogenation for production of thermally stable jet fuels; Design of a batch mode and a continuous mode three-phase reactor system for the liquefaction of coal and upgrading of coal liquids; and Exploratory studies on coal liquids upgrading using mesopores molecular sieve catalysts. 136 refs., 69 figs., 24 tabs.

Progress report of Technical Physics Division: April 1980 - March 1982

International Nuclear Information System (INIS)

Chaudhry, Ramesh; Vijendran, P.

1983-01-01

Activities, with an individual summary of each, of the Technical Physics Division (TPD) of the Bhabha Atomic Research Centre (BARC), Bombay are reported for the period April 1980 - March 1982. The major thrust of the TPD's work has been in: (i) design and fabrication of instruments, devices and equipment and (ii) development of techniques in the frontline research and technology areas like vacuum science, surface analysis, cryogenics and crystal growing. The Division also provided custombuilt electronics equipment, vacuum systems and glass components and devices to the various Divisions of BARC and other units of the DAE. Training and manpower development activities and technology transfer activities are also reported. Lists of seminars, colloquia, publications during the period of the report are given. (M.G.B.)

Technical minutes of the ninth INDC meeting. Vienna, 16-20 May 1977

International Nuclear Information System (INIS)

Motz, H.

1978-05-01

Progress reports from data centres on data measurements, facilities and evaluations, on coordinating activities are presented along with reports of technical, ad-hoc and policy subcommittees, on plans for cooperation and past meetings

Ghrelin and cancer progression.

Science.gov (United States)

Lin, Tsung-Chieh; Hsiao, Michael

2017-08-01

Ghrelin is a small peptide with 28 amino acids, and has been characterized as the ligand of the growth hormone secretagogue receptor (GHSR). In addition to its original function in stimulating pituitary growth hormone release, ghrelin is multifunctional and plays a role in the regulation of energy balance, gastric acid release, appetite, insulin secretion, gastric motility and the turnover of gastric and intestinal mucosa. The discovery of ghrelin and GHSR expression beyond normal tissues suggests its role other than physiological function. Emerging evidences have revealed ghrelin's function in regulating several processes related to cancer progression, especially in metastasis and proliferation. We further show the relative GHRL and GHSR expression in pan-cancers from The Cancer Genome Atlas (TCGA), suggesting the potential pathological role of the axis in cancers. This review focuses on ghrelin's biological function in cancer progression, and reveals its clinical significance especially the impact on cancer patient outcome. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

Crystal growth from low-temperature solutions

International Nuclear Information System (INIS)

Sangwal, K.

1994-01-01

The state of the art in crystal growth from solutions at low-temperatures has been done. The thermodynamic and kinetic parameters have been discussed in respect to different systems. The methods of crystal growth from water and organic solutions and different variants of their technical realizations have been reviewed. Also the growth by chemical reactions and gel growth have been described. The large number of examples have been shown. 21 refs, 30 figs, 3 tabs

Technical Adequacy of the easyCBM[R] Mathematics Measures: Grades 3-8, 2009-2010 Version. Technical Report #1007

Science.gov (United States)

Nese, Joseph F. T.; Lai, Cheng-Fei; Anderson, Daniel; Jamgochian, Elisa M.; Kamata, Akihito; Saez, Leilani; Park, Bitnara J.; Alonzo, Julie; Tindal, Gerald

2010-01-01

In this technical report, data are presented on the practical utility, reliability, and validity of the easyCBM[R] mathematics (2009-2010 version) measures for students in grades 3-8 within four districts in two states. Analyses include: minimum acceptable within-year growth; minimum acceptable year-end benchmark performance; internal and…

University of Florida, University research program in robotics. Annual technical progress report

International Nuclear Information System (INIS)

Crane, C.D. III; Tulenko, J.S.

1994-05-01

Progress is reported in the areas of environmental hardening, database, world modeling, vision, man-machine interface, advanced liquid metal reactor inspection robot, and articulated transporter/manipulator system (ATMS) development

University of Florida, University research program in robotics. Annual technical progress report

Energy Technology Data Exchange (ETDEWEB)

Crane, C.D. III; Tulenko, J.S.

1994-05-01

Progress is reported in the areas of environmental hardening, database, world modeling, vision, man-machine interface, advanced liquid metal reactor inspection robot, and articulated transporter/manipulator system (ATMS) development.

Post-Keynesyen Talep Yönelimli Büyüme Modelleri(Post-Keynesian Demand Oriented Growth Models

Directory of Open Access Journals (Sweden)

Yelda Bugay TEKGÜL

2013-12-01

Full Text Available Economic literature generally contains growth models dominated by classical/neo-classical approach. These models focused on the differences in the growth rates among countries in terms of supply of factors of production. Wheras capital accumulation and technical progress are viewed as the main determinant of the growth, increase in per-capita income is only determined by supply-side factors. Should the economy is in the position of under-employment and under-capacity, then these approaches are not capable of satisfactory explanation for the economic growth. Assumptions of supply-side approach are endogenous regarding the economic system and restricted by the demand. In an open economy, growth can be defined as a component of a Keynesian demand-oriented economic system and it is genarally called as Post-Keynesian growth models. These models have been developed on two main axes: “Export-led growth model”, introduced by N. Kaldor and “balance-of-payment constrained growth model”introduced by A.P.Thirwall in 1979. Export-led growth model is based on the assumption that internally determined productivity increases generate a virtous circle economy. Balance-of-payment constrained growth model, on the other hand, is based on the assumption that foreign trade deficit cannot continue forever and that long-run growth rate is a function of the export and elasticity of demand for import of the country. The objective of this paper is to discuss and critisize export-led growth and balance-of-payment constrained growth model.

The mathematics and mechanics of biological growth

CERN Document Server

Goriely, Alain

2017-01-01

This monograph presents a general mechanical theory for biological growth. It provides both a conceptual and a technical foundation for the understanding and analysis of problems arising in biology and physiology. The theory and methods is illustrated on a wide range of examples and applications. A process of extreme complexity, growth plays a fundamental role in many biological processes and is considered to be the hallmark of life itself. Its description has been one of the fundamental problems of life sciences, but until recently, it has not attracted much attention from mathematicians, physicists, and engineers. The author herein presents the first major technical monograph on the problem of growth since D’Arcy Wentworth Thompson’s 1917 book On Growth and Form. The emphasis of the book is on the proper mathematical formulation of growth kinematics and mechanics. Accordingly, the discussion proceeds in order of complexity and the book is divided into five parts. First, a general introduction on the pro...

Growth trajectories of mathematics achievement: Longitudinal tracking of student academic progress.

Science.gov (United States)

Mok, Magdalena M C; McInerney, Dennis M; Zhu, Jinxin; Or, Anthony

2015-06-01

A number of methods to investigate growth have been reported in the literature, including hierarchical linear modelling (HLM), latent growth modelling (LGM), and multidimensional scaling applied to longitudinal profile analysis (LPAMS). This study aimed at modelling the mathematics growth of students over a span of 6 years from Grade 3 to Grade 9. The sample comprised secondary longitudinal data collected in three waves from n = 866 Hong Kong students when they were in Grade 3, Grade 6, and Grade 9. Mathematics achievement was measured thrice on a vertical scale linked with anchor items. Linear and nonlinear latent growth models were used to assess students' growth. Gender differences were also examined. A nonlinear latent growth curve with a decelerated rate had a good fit to the data. Initial achievement and growth rate were negatively correlated. No gender difference was found. Mathematics growth from Grade 6 to Grade 9 was slower than that from Grade 3 to Grade 6. Students with lower initial achievement improved at a faster rate than those who started at a higher level. Gender did not affect growth rate. © 2014 The British Psychological Society.

Influence of admission marks on the academic performance of technical architecture students

OpenAIRE

Gaspar Fàbregas, Kàtia; Núñez Andrés, María Amparo; Rodríguez Jordana, Juan; Jordana Riba, Francisco de Paula

2016-01-01

Traditionally, students from higher training cycle and upper secondary school education access higher technical education with a wide range of access marks in each group. The purpose of this article is to analyse how students’ backgrounds and access marks really influence their success in the first academic year and further evolution to obtain the degree of Technical Architecture. To achieve this aim, the progress of students from different backgrounds was analysed for three acade...

Progress Report for Period Ending December 1961. Department of Reactor Physics

Energy Technology Data Exchange (ETDEWEB)

Tell, B [ed.

1962-08-15

This is the second Progress Report from the Department for Reactor Physics of Aktiebolaget Atomenergi, which is issued for the information of institutions and persons interested in the progress of the work. In this report the activities of the General Physics Section have been included, since this section nowadays belongs to the department. This is merely an informal progress report, and the results and data presented must be taken as preliminary. Final results will be submitted for publication either in the regular technical journals or as monographs in the series AE-reports.

Crystalline Repository Project. Technical progress report, October 1982-March 1983

International Nuclear Information System (INIS)

1985-01-01

This document reports the progress being made periodically on the development of a geologic repository in crystalline rock for the permanent disposal of high-level nuclear waste. The reporting elements are arranged by the work breakdown structure so that related studies are presented together. The studies are reported by the Office of Crystalline Respository Development (OCRD), a prime contractor of the US Department of Energy Repository Project Office. The studies include work by other prime contractors and by subcontractors to OCRD

Towards a space-borne quantum gravity gradiometer: progress in laboratory demonstration

Science.gov (United States)

Yu, Nan; Kohel, James M.; Kellogg, James R.; Maleki, Lute

2005-01-01

This paper describes the working principles and technical benefits of atom-wave interferometer-based inertial sensors, and gives a progress report on the development of a quantum gravity gradiometer for space applications at JPL.

Association Euratom - Risø National Laboratory, Technical University of Denmark - Annual Progress Report 2007

DEFF Research Database (Denmark)

Michelsen, Poul; Korsholm, Søren Bang; Juul Rasmussen, Jens

The programme of the Research Unit of the Fusion Association Euratom - Risø National Laboratory, Technical University of Denmark, covers work in fusion plasma physics and in fusion technology. The fusion plasma physics research focuses on turbulence and transport, and its interaction with the pla......The programme of the Research Unit of the Fusion Association Euratom - Risø National Laboratory, Technical University of Denmark, covers work in fusion plasma physics and in fusion technology. The fusion plasma physics research focuses on turbulence and transport, and its interaction...... phased out during 2007. Minor activities are system analysis, initiative to involve Danish industry in ITER contracts and public information. A summary is presented of the results obtained in the Research Unit during 2007....

Particle beam fusion progress report, January-June 1980

International Nuclear Information System (INIS)

1981-05-01

An overview and technical summaries are given for research progress in each of the following general areas: (1) fusion target studies; (2) target experiments; (3) particle beam source theory; (4) diagnostics development; (5) particle beam experiments; (6) pulsed power research and development; (7) pulse power application; and (8) Electron Beam Fusion Accelerator project

Agricultural productivity growth and technology progress in ...

African Journals Online (AJOL)

The goal of this investigation was to analyze the impact of some variables of production(input) on agricultural productivity growth (output) in China over the period 1989-2002. To this aim, Cobb-Douglas function has been used. The methodology used in this study is correct and the resulting conclusion is that labor, capital ...

Pterostilbene acts through metastasis-associated protein 1 to inhibit tumor growth, progression and metastasis in prostate cancer.

Directory of Open Access Journals (Sweden)

Kun Li

Full Text Available The development of natural product agents with targeted strategies holds promise for enhanced anticancer therapy with reduced drug-associated side effects. Resveratrol found in red wine, has anticancer activity in various tumor types. We reported earlier on a new molecular target of resveratrol, the metastasis-associated protein 1 (MTA1, which is a part of nucleosome remodeling and deacetylation (NuRD co-repressor complex that mediates gene silencing. We identified resveratrol as a regulator of MTA1/NuRD complex and re-activator of p53 acetylation in prostate cancer (PCa. In the current study, we addressed whether resveratrol analogues also possess the ability to inhibit MTA1 and to reverse p53 deacetylation. We demonstrated that pterostilbene (PTER, found in blueberries, had greater increase in MTA1-mediated p53 acetylation, confirming superior potency over resveratrol as dietary epigenetic agent. In orthotopic PCa xenografts, resveratrol and PTER significantly inhibited tumor growth, progression, local invasion and spontaneous metastasis. Furthermore, MTA1-knockdown sensitized cells to these agents resulting in additional reduction of tumor progression and metastasis. The reduction was dependent on MTA1 signaling showing increased p53 acetylation, higher apoptotic index and less angiogenesis in vivo in all xenografts treated with the compounds, and particularly with PTER. Altogether, our results indicate MTA1 as a major contributor in prostate tumor malignant progression, and support the use of strategies targeting MTA1. Our strong pre-clinical data indicate PTER as a potent, selective and pharmacologically safe natural product that may be tested in advanced PCa.

Theoretical particle physics. Technical progress report, May 1, 1985-April 30, 1986

International Nuclear Information System (INIS)

Gottlieb, S.A.; Hendry, A.W.; Kostelecky, V.A.; Lichtenberg, D.B.

1986-05-01

Research activities during this past year included theoretical work in lattice gauge theory, EMC effect, supersymmetry and supergravity, weak interactions including CP violation, and superstrings. Progress in all these areas is reported

Explaining African Growth Performance: A Production-Frontier Approach

OpenAIRE

Romain Houssa; Oleg Badunenko; Daniel J. Henderson

2010-01-01

This paper employs a production frontier approach that allows distinguishing technologic progress from efficiency development. Data on 35 African countries in 1970-2007 show that efficiency losses have constrained growth in Africa while technology progress has played a marginal growth enhancing role in the region. Moreover, physical and human capital accumulation are the main factors that drive productivity growth at the country level. Examining the outcomes of successful countries suggests t...

NAEP 1999 Long-Term Trend Technical Analysis Report: Three Decades of Student Performance. NCES 2005-484

Science.gov (United States)

Allen, Nancy L.; McClellan, Catherine A.; Stoeckel, Joan J.

2005-01-01

This report provides an update to the technical analysis procedures documenting the 1996 National Assessment of Educational Progress (NAEP) as presented in "The NAEP 1996 Technical Report" (Allen, Carlson, and Zelenak, 1999). It describes how the 1999 long-term trend data were incorporated into the trend analyses. Since no national main…

Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study. The North America ALS/IGF-I Study Group.

Science.gov (United States)

Lai, E C; Felice, K J; Festoff, B W; Gawel, M J; Gelinas, D F; Kratz, R; Murphy, M F; Natter, H M; Norris, F H; Rudnicki, S A

1997-12-01

The objective of this study was to investigate the safety and efficacy of recombinant human insulinlike growth factor-I (rhIGF-I) in the treatment of sporadic ALS. A double-blind, placebo-controlled, randomized study of 266 patients was conducted at eight centers in North America. Placebo or rhIGF-I (0.05 mg/kg/day or 0.10 mg/kg/day) was administered for 9 months. The primary outcome measure was disease symptom progression, assessed by the rate of change (per patient slope) in the Appel ALS rating scale total score. The Sickness Impact Profile (SIP), a patient-perceived, health-related quality of life assessment, was a secondary outcome variable. Progression of functional impairment in patients receiving high-dose (0.10 mg/kg/day) rhIGF-I was 26% slower than in patients receiving placebo (p = 0.01). The high-dose treatment group was less likely to terminate the study due to protocol-defined markers of disease symptom progression, and members in this group exhibited a slower decline in quality of life, as assessed by the SIP. Patients receiving 0.05 mg/kg/day of rhIGF-I exhibited trends similar to those associated with high-dose treatment, suggesting a dose-dependent response. The incidence of clinically significant adverse experiences was comparable among the three treatment groups. Recombinant human insulin-like growth factor-I slowed the progression of functional impairment and the decline in health-related quality of life in patients with ALS with no medically important adverse effects.

Assuring PSA technical adequacy for new advanced light water reactor designs

International Nuclear Information System (INIS)

Lutz, R.J.; Detar, H.L.; Schneider, R.E.

2012-01-01

The Probabilistic Safety Assessment (PSA) for an Advanced Light Water Reactor (ALWR) must exhibit a high level of technical adequacy, or technical quality, in order to be used as a reliable tool for making risk informed decisions concerning design and eventual operation of the plant. During the design phase, decisions on some design features may use the PSA as an input. Also, the PSA may be used as input to other operational decisions during plant design and construction including the development of procedures, development of technical specification limiting conditions for operation and scheduling of preventive maintenance activities. For the existing fleet of light water reactors (LWRs), PSA technical adequacy can be judged from wide ranging acceptance criteria such as the PRA (Probabilistic Risk Assessment) Standard in the United States of America that was developed jointly by the American Society of Mechanical Engineers (ASME) and the American Nuclear Society (ANS). However, the requirements for PRA technical adequacy in this PRA Standard assumes that the plant is built and has operation experience. Some of the requirements cannot be met for ALWRs in the design or construction phase and with no operational history. Key elements of a high level of technical adequacy include procedures, operator interviews, plant walk-downs and equipment reliability histories. The ability to include these key elements into the ALWR PSA to improve technical adequacy will progress as the ALWR progresses from the design stage through the construction stage and finally to the fuel load / pre-operational stage. As the technical adequacy becomes more robust, more confidence can be placed on risk-informed decisions that are made with the PSA. To assist in using the PSA as input to design and operational decisions in the design and construction stages of an ALWR, an addition to the ASME/ANS PRA Standard is being developed. The intent of this addition to the Standard is to provide

Pillars of peace: The evolution of nuclear technical cooperation

International Nuclear Information System (INIS)

Cetto, A.M.

2003-01-01

The twentieth century witnessed unprecedented scientific and technological progress, unfortunately paralleled by the development of weapons of mass destruction. And with this progress came an incredible amount of responsibility for scientists and governments. The creation of the IAEA and its technical cooperation programme brought together scientists and governments to use nuclear technology for the 'peaceful pursuits of mankind'. The programme supports application of nuclear techniques to solve socio-economic and human development problems in areas as diverse as agriculture, health, natural resource management, and radiation protection. Fifty years after President Eisenhower's famous 'Atoms for Peace' speech, the IAEA technical cooperation programme provides more than $70 million worth of experts, training, and procurement services each year to approximately 75% of its 137 Member States. But as development budgets shrink, the programme is seeking to make more meaningful use of resources at hand (national capacities, regional resources, development partners and the voluntary Technical Cooperation Fund), targeting specific problems of Member States and partnering with other sustainable development organizations. At the same time, efforts continue to overcome the past legacy that necessitated the 'Atoms for Peace' proposal in the first place. Even as development challenges are addressed, the IAEA, its partners and governments face other challenges along the way, including public opinion for a technology that had a devastating global introduction

[Shippingport Station Decommissioning Project]: FY 1987 annual progress report, October 1, 1986-September 30, 1987

International Nuclear Information System (INIS)

1988-01-01

This report presents progress on the Shippingport Station Decommissioning Project for FY 1987. There are two main topics: Project Management and Decommissioning Project Activities. Changes from technical and managerial concepts developed in the original Decommissioning Plan are presented with the related technical, economic, or schedule considerations. 3 refs., 9 figs., 4 tabs

Shippingport Station Decommissioning Project: FY 1988 annual progress report, October 1, 1987--September 30, 1988

International Nuclear Information System (INIS)

1989-01-01

This report presents progress on the Shippingport Station Decommissioning Project for FY 1988. There are two main topics: Project Management and Decommissioning Project Activities. Changes from technical and managerial concepts developed in the original Decommissioning Plan are presented with the related technical, economic, or schedular considerations. 4 refs., 17 figs., 2 tabs

Biogas Opportunities Roadmap Progress Report

Energy Technology Data Exchange (ETDEWEB)

None, None

2015-12-01

In support of the Obama Administration's Climate Action Plan, the U.S. Department of Energy, the U.S. Environmental Protection Agency, and U.S. Department of Agriculture jointly released the Biogas Opportunities Roadmap Progress Report, updating the federal government's progress to reduce methane emissions through biogas systems since the Biogas Opportunities Roadmap was completed by the three agencies in July 2014. The report highlights actions taken, outlines challenges and opportunities, and identifies next steps to the growth of a robust biogas industry.

On climate change and economic growth

International Nuclear Information System (INIS)

Fankhauser, Samuel; Tol, Richard S.J.

2005-01-01

The economic impact of climate change is usually measured as the extent to which the climate of a given period affects social welfare in that period. This static approach ignores the dynamic effects through which climate change may affect economic growth and hence future welfare. In this paper we take a closer look at these dynamic effects, in particular saving and capital accumulation. With a constant savings rate, a lower output due to climate change will lead to a proportionate reduction in investment which in turn will depress future production (capital accumulation effect) and, in almost all cases, future consumption per capita. If the savings rate is endogenous, forward looking agents would change their savings behavior to accommodate the impact of future climate change. This suppresses growth prospects in absolute and per capita terms (savings effect). In an endogenous growth context, these two effects may be exacerbated through changes in labour productivity and the rate of technical progress. Simulations using a simple climate-economy model suggest that the capital accumulation effect is important, especially if technological change is endogenous, and may be larger than the direct impact of climate change. The savings effect is less pronounced. The dynamic effects are more important, relative to the direct effects, if climate change impacts are moderate overall. This suggests that they are more of a concern in developed countries, which are believed to be less vulnerable to climate change. The magnitude of dynamic effects is not sensitive to the choice of discount rate

Hydrogen storage - are we making progress?

International Nuclear Information System (INIS)

Blair, L.; Milliken, J.; Satyapal, S.

2004-01-01

'Full text:' The efficient storage of hydrogen in compact, lightweight systems that allow greater than 300-mile range has been identified as one of the major technical challenges facing the practical commercialization of fuel cell power systems for light-duty vehicles. Following the hydrogen vision announced by President Bush in his 2003 State of the Union address, the U.S. Department of Energy issued a Grand Challenge, soliciting ideas from universities, national laboratories, and industry. DOE's National Hydrogen Storage Project, an aggressive and innovative research program focused on materials R and D, will be launched in Fiscal Year 2005. An intensive effort is also underway in the private sector, both in the U.S. and abroad, to meet the challenging on-board hydrogen storage requirements. A historical perspective of hydrogen storage research and development will be provided and the current DOE technical targets for hydrogen storage systems will be discussed. The state-of-the-art in hydrogen storage will be summarized and recent progress assessed. Finally future research directions and areas of technical emphasis will be described. (author)

ITER technology R and D progress report. Report by the Director. ITER technical advisory committee meeting, 25-27 June 2000, St. Petersburg

International Nuclear Information System (INIS)

2001-01-01

The overall philosophy for the ITER design has been to use established approaches through detailed analysis and to validate their application to ITER through technology R and D, including fabrication of full scale or scalable models of key components. All this R and D work has been done for ITER under collaboration among the Home Teams, with a total resource of about 660 KIUA. R and D issues for ITER-FEAT are almost the same as for the 1998 ITER design. Major developments and fabrication have been completed and tests have significantly progressed. The technical output from the R and D validates the technologies and confirms the manufacturing techniques and quality assurance incorporated in the ITER design, and supports the manufacturing cost estimates for important key cost drivers. The testing of models is continuing to demonstrate their performance margin and/or to optimize their operational use. Their realisation offers insights useful for a possible future collaborative construction activity. Valuable and relevant experience has already been gained in the management of industrial scale, cross-party ventures. The successful progress of these projects increases confidence in the possibility of jointly constructing ITER in an international project framework. The R and D present status is summarized in the following: details are given in Chapters 2 and 3. Significant efforts and resources have been devoted to the Seven Large R and D Projects which cover all the major key components of the basic machine of ITER and their maintenance tools

Fusion reactor materials semiannual progress report for period ending September 30, 1990

International Nuclear Information System (INIS)

1991-04-01

This is the ninth in series of semiannual technical progress reports on fusion reactor materials. This report combines research and development activities which were previously reported separately in the following technical progress reports: Alloy Development of Irradiation Performance; Damage Analysis and Fundamental Studies; and Special Purpose Materials. These activities are concerned principally with the effects of the neutronic and chemical environment on the properties and performance of reactor materials; together they form one element of the overall materials program being conducted in support of the Magnetic Fusion Energy Program of the US Department of Energy. The other major element of the program is concerned with the interactions between reactor materials and the plasma and is reported separately. The Fusion Reactor Materials Program is a national effort involving several national laboratories, universities, and industries. The purpose of this series of reports is to provide a working technical record for the use of the program participants, and to provide a means of communicating the efforts of materials scientists to the rest of the fusion community, both nationally and worldwide

Fusion reactor materials: Semiannual progress report for period ending September 30, 1987

International Nuclear Information System (INIS)

1988-03-01

This is the third in a series of semiannual technical progress reports on fusion reactor materials. This report combines research and development activities which were previously reported separately in the following technical progress reports: Alloy Development for Irradiation Performances; Damage Analysis and Fundamental Studies; Special Purpose Materials. These activities are concerned principally with the effects of the neutronic and chemical environment on the properties and performance of reactor materials; together they form one element of the overall materials program being conducted in support of the Magnetic Fusion Energy Program of the US Department of Energy. The other major element of the program is concerned with the interactions between reactor materials and the plasma and is reported separately. The Fusion Reactor Materials Program is a national effort involving several national laboratories, universities, and industries. The purpose of this series of reports is to provide a working technical record for the use of the program participants, and to provide a means of communicating the efforts of materials scientists to the rest of the fusion community, both nationally and worldwide

Contribution of population growth to per capita income and sectoral output growth in Japan, 1880-1970.

Science.gov (United States)

Yamaguchi, M; Kennedy, G

1984-09-01

The authors measured the positive and negative contributions of population and labor force growth to the growth of per capita income and sectoral output in Japan in the 1880-1970 period. A 2-sector growth accounting model that treats population and labor growth as separate variables was used. 3 alternative methods were used: the Residual method, the Verdoorn method, and the factor augmenting rate method. The total contribution of population cum labor growth to per capita income growth tended to be negative in the 1880-1930 period and positive in the 1930-40 and 1950-70. Over the 1880-1970 period as a whole, population cum labor growth made a positive contribution to per capita income growth under the Residual method (0.35%/year), the factor augmenting rate method (0.29%/year), and the Verdoorn method (0.01%/year). In addition, population cum labor growth contributed positively to sectoral output growth. The average contribution to agricultural output growth ranged from 1.03% (Verdoorn) - 1.46%/year (factor augmenting rate), while the average contribution to nonagricultural output growth ranged from 1.22% (Verdoorn) - 1.60%/year (Residual). Although these results are dependent on the model used, the fact that all 3 methods yielded consistent results suggests that population cum labor growth did make a positive contribution to per capita income and sectoral output growth in Japan. These findings imply that in economies where the rate of technical change in agricultural and nonagricultural sectors exceeds population growth, policies that reduce agricultural elasticities may be preferable; on the other hand, policies that reduce agricultural elasticities are to be avoided in economies with low rates of technical change. Moreover, in the early stages of economic development, policies that increase agricultural income and price elasticities should be considered.

Aircraft Nuclear Propulsion Project Quarterly Progress Report for Period Ending December 31, 1956

Energy Technology Data Exchange (ETDEWEB)

NA, NA [ORNL

1957-03-12

This quarterly progress report of the Aircraft Nuclear Propulsion Project at ORNL records the technical progress of research on circulating-fuel reactors and other ANP research at the Laboratory. The report is divided into five major parts: 1) Aircraft Reactor Engineering, 2) Chemistry, and 3) Metallurgy, 4) Heat Transfer and Physical Properties, Radiation Damage, and Fuel Recovery and Reprocessing, and 5) Reactor Shielding.

Symbol manipulation by computer applied to plasma physics. Technical progress report 2

International Nuclear Information System (INIS)

Rosen, B.

1977-09-01

Progress has been made in automating the calculation of parametric processes analytically by computer. The computations are performed automatically to lowest order quickly and efficiently. Work has started on a method for solving the nonlinear differential equations describing interacting modes

Experimental studies of elementary particle interactions at high energies: Technical progress report

International Nuclear Information System (INIS)

1987-01-01

This paper discusses progress of experiments at CERN and Fermilab. At CERN, data accumulation and analysis is discussed for the UA-6 experiment, which involves proton-antiproton collisions. At Fermilab, the testing of a collider detector for the Tevatron is discussed

Towards a European draft code of practice in creep crack growth testing

International Nuclear Information System (INIS)

Nikbin, K.M.

2003-01-01

Crack growth and initiation models as well as defect assessment codes need reliable and verifiable material properties data for use in their predictive methodologies. These data consist of uniaxial, multiaxial and crack initiation and growth data under static and cyclic loading at the relevant temperatures. International collaboration for developing standards in this field started in 1987 under the auspices of the VAMAS (Versailles Agreement for MAterials and Standards). Two technical Working Areas TWA11 and TWA19 committees ending 1998 have made substantial progress in unifying and standardising the methods for obtaining the relevant data. This collaboration has resulted in the development of ASTM E1457 creep crack growth testing standard. The European collaborative programme CRETE (see Acknowledgements), which began in 1999, is following up this valuable research in order to develop a European Code of Practice for elevated temperature crack growth which is planned to have a wider field of application. A Round Robin experimental, analytical and verification programme in CRETE will include testing a type 316 LN stainless steel at 550 degC and a Carbon-Manganese steel at 400 degC consisting of seven different geometries. The paper reviews the methods of analysis used for laboratory creep crack growth data and their relevance to long term crack initiation and growth in components. In addition, since design and life assessment and material properties under creep are an integral part of this project a short review of the models available for predicting creep and fatigue crack growth is presented. (author)

US carbon emissions, technological progress and economic growth since 1870

International Nuclear Information System (INIS)

Huntington, H.G.

2005-01-01

The long-term US experience emphasises the importance of controlling for electrification and other major technology transformations when evaluating the growth of carbon emissions at different stages of development. Prior to World War I, carbon emissions grew faster than economic growth by 2.3% per year. As electricity use expanded and steam engines became much larger, carbon emissions began to grow slower than economic growth by 1.6% per year. Adjusting to this technological shift, an expanding economy continues to increase carbon emissions by about 9% for each 10% faster growth. There is little evidence of a decline in this elasticity as the income level rises. These results suggest that the USA today will need to find additional policies to curb carbon emissions if it wishes to prevent any further increase in its per capita emissions, and if its per capita economy grows by more than 1.8% per year. (Author)

Microwave plasma source for neutral-beam injection systems. Quarterly technical progress report

International Nuclear Information System (INIS)

1981-01-01

The overall program is described and the technical and programmatic reasons for the decision to pursue both the RFI and ECH sources into the current hydrogen test stage is discussed. We consider the general characteristics of plasma sources in the parameter regime of interest for neutral beam applications. The operatonal characteristics, advantages and potential problems of RFI and ECH sources are discussed. In these latter two sections we rely heavily on experience derived from developing RFI and ECH ion engine sources for NASA

Maryland University sectored isochronous cyclotron (MUSIC): Progress report No. 11

Energy Technology Data Exchange (ETDEWEB)

1966-10-10

Technical progress during the past quarter has contributed to increased confidence that MUSIC will exceed its desired performance characteristics in all respects. Design studies on the magnet indicate that a field has been obtained capable of accelerating protons above the 112 MeV design objective. Initial rf study and design work indicates no major technical problems, although there are many difficult engineering problems to be solved. Center studies are just being started. Building installation and interface problems are being dealt with effectively, and no significant problems are anticipated in this area.

Technical Safety Appraisal of the Rocky Flats Plant

Energy Technology Data Exchange (ETDEWEB)

Brown, Blake P.

1989-01-01

This report provides the results of a Technical Safety Appraisal (TSA) of the Rocky Flats Plant (RFP) conducted November 14 to 18 and November 28 to December 9, 1988. This appraisal covered the effectiveness and improvements in the RFP safety program across the site, evaluating progress to date against standards of accepted practice. The appraisal included coverage of the timeliness and effectiveness of actions taken in response to the recommendations/concerns in three previous Technical Safety Appraisals (TSAs) of RFP Bldg. 707 conducted in July 1986, Bldgs. 771/774 conducted in October/November 1986, and Bldgs. 776/777 conducted in January/February 1988. Results of this appraisal are given in Section IV for each of 14 technical safety areas at RFP. These results include a discussion, conclusions and any new safety concerns for each technical safety area. Appendix A contains a description of the system for categorizing concerns, and the concerns are tabulated in Appendix B. Appendix C reports on the evaluation of the contractor's actions and the current status of each of the 230 recommendations and concerns contained in the three previous TSA reports.

Technical efficiency and productivity of Chinese county hospitals: an exploratory study in Henan province, China

Science.gov (United States)

Cheng, Zhaohui; Tao, Hongbing; Cai, Miao; Lin, Haifeng; Lin, Xiaojun; Shu, Qin; Zhang, Ru-ning

2015-01-01

Objectives Chinese county hospitals have been excessively enlarging their scale during the healthcare reform since 2009. The purpose of this paper is to examine the technical efficiency and productivity of county hospitals during the reform process, and to determine whether, and how, efficiency is affected by various factors. Setting and participants 114 sample county hospitals were selected from Henan province, China, from 2010 to 2012. Outcome measures Data envelopment analysis was employed to estimate the technical and scale efficiency of sample hospitals. The Malmquist index was used to calculate productivity changes over time. Tobit regression was used to regress against 4 environmental factors and 5 institutional factors that affected the technical efficiency. Results (1) 112 (98.2%), 112 (98.2%) and 104 (91.2%) of the 114 sample hospitals ran inefficiently in 2010, 2011 and 2012, with average technical efficiency of 0.697, 0.748 and 0.790, respectively. (2) On average, during 2010–2012, productivity of sample county hospitals increased by 7.8%, which was produced by the progress in technical efficiency changes and technological changes of 0.9% and 6.8%, respectively. (3) Tobit regression analysis indicated that government subsidy, hospital size with above 618 beds and average length of stay assumed a negative sign with technical efficiency; bed occupancy rate, ratio of beds to nurses and ratio of nurses to physicians assumed a positive sign with technical efficiency. Conclusions There was considerable space for technical efficiency improvement in Henan county hospitals. During 2010–2012, sample hospitals experienced productivity progress; however, the adverse change in pure technical efficiency should be emphasised. Moreover, according to the Tobit results, policy interventions that strictly supervise hospital bed scale, shorten the average length of stay and coordinate the proportion among physicians, nurses and beds, would benefit hospital efficiency

TECHNICAL TRAINING SEMINAR: High Temperature Superconductors: Progress and Issues

CERN Multimedia

Davide Vitè

2002-01-01

Monday 24 June from 14:30 to 15:30 - Training Centre Auditorium - bldg. 593-11 High Temperature Superconductors: Progress and Issues Prof. Jan Evetts / UNIVERSITY OF CAMBRIDGE, Department of Materials Science and Metallurgy, UK Grappling with grain boundaries: Current transport processes in granular High Temperature Superconductors (HTS) The development of High Temperature Superconductors, seen from a materials scientist's point of view, is relevant to the superconductivity community at CERN: their possible high current applications can include high performance magnets for future accelerators. There is an urgent need to develop a quantitative description of HTS conductors in terms of their complex anisotropy, inhomogeneity and dimensionality. This is essential both for the practical specification of a conductor and for charting routes to conductor optimisation. The critical current, the n-value, dissipation and quenching characteristics are amongst most important parameters that make up an engineering specifi...

Growth Trajectories of Mathematics Achievement: Longitudinal Tracking of Student Academic Progress

Science.gov (United States)

Mok, Magdalena M. C.; McInerney, Dennis M.; Zhu, Jinxin; Or, Anthony

2015-01-01

Background: A number of methods to investigate growth have been reported in the literature, including hierarchical linear modelling (HLM), latent growth modelling (LGM), and multidimensional scaling applied to longitudinal profile analysis (LPAMS). Aims: This study aimed at modelling the mathematics growth of students over a span of 6 years from…

Seminar Pediatrics. Medical and Technical Applications

International Nuclear Information System (INIS)

Montivero, M.; Nespral, D.O.; Alak, Maria del Carmen

2012-01-01

The Association of Biology and Nuclear Medicine has organized the 'Seminar Pediatrics - Medical and Technical Applications', held in Buenos Aires in May 2012, in order to collaborate with the scientific growth of nuclear medicine in pediatrics. The main topics covered were: management of pediatric patients and medical application in childhood, dosimetry in pediatric nuclear medicine, scope of radioisotope - studies in nephrourological pathologies, PET in pediatrics, among others.

Nuclear waste management. Semiannual progress report, October 1982-March 1983

International Nuclear Information System (INIS)

Chikalla, T.D.; Powell, J.A.

1983-06-01

This document is one of a series of technical progress reports designed to report radioactive waste management programs at the Pacific Northwest Laboratory. Accomplishments in the following programs are reported: waste stabilization; Materials Characterization Center; waste isolation; low-level waste management; remedial action; and supporting studies

Commercial LFCM vitrification technology. Quarterly progress report, October-December 1984

Energy Technology Data Exchange (ETDEWEB)

Burkholder, H.C.; Jarrett, J.H. (comps.)

1985-07-01

This report is the first in a series of quarterly reports compiled by the Nuclear Waste Treatment Program Office at Pacific Northwest Laboratory to document progress on commercial liquid-fed ceramic melter (LFCM) vitrification technology. Progress in the following technical subject areas during the first quarter of FY 1985 is discussed: pretreatment systems, melting process chemistry, glass development and characterization, feed preparation and transfer systems, melter systems, canister filling and handling systems, off-gas systems, process/product modeling and control, and supporting studies. 33 figs., 12 tabs.

Shippingport Station Decommissioning Project: FY 1986 annual progress report, October 1, 1985 through September 30, 1986

International Nuclear Information System (INIS)

1987-01-01

This report presents progress on the Shippingport Station Decommissioning Project for FY 1986. There are two main topics: Project Management and Decommissioning Project Activities. Changes from technical and managerial concepts developed in the original Decommissioning Plan are presented with the related technical, economic, or schedule considerations. 9 refs., 4 figs., 3 tabs

Core Capabilities and Technical Enhancement -- FY-98 Annual Report

Energy Technology Data Exchange (ETDEWEB)

Miller, David Lynn

1999-04-01

The Core Capability and Technical Enhancement (CC&TE) Program, a part of the Verification, Validation, and Engineering Assessment Program, was implemented to enhance and augment the technical capabilities of the Idaho National Engineering and Environmental Laboratory (INEEL). The purpose for strengthening the technical capabilities of the INEEL is to provide the technical base to serve effectively as the Environmental Management Laboratory for the Office of Environmental Management (EM). An analysis of EM's science and technology needs as well as the technology investments currently being made by EM across the complex was used to formulate a portfolio of research activities designed to address EM's needs without overlapping work being done elsewhere. An additional purpose is to enhance and maintain the technical capabilities and research infrastructure at the INEEL. This is a progress report for fiscal year 1998 for the five CC&TE research investment areas: (a) transport aspects of selective mass transport agents, (b) chemistry of environmental surfaces, (c) materials dynamics, (d) characterization science, and (e) computational simulation of mechanical and chemical systems. In addition to the five purely technical research areas, this report deals with the science and technology foundations element of the CC&TE from the standpoint of program management and complex-wide issues. This report also provides details of ongoing and future work in all six areas.

Core capabilities and technical enhancement, FY-98 annual report

Energy Technology Data Exchange (ETDEWEB)

Miller, D.L.

1999-04-01

The Core Capability and Technical Enhancement (CCTE) Program, a part of the Verification, Validation, and Engineering Assessment Program, was implemented to enhance and augment the technical capabilities of the Idaho National Engineering and Environmental Laboratory (INEEL). The purpose for strengthening the technical capabilities of the INEEL is to provide the technical base to serve effectively as the Environmental Management Laboratory for the Department of Energy's Office of Environmental Management (EM). An analysis of EM's science and technology needs as well as the technology investments currently being made by EM across the complex was used to formulate a portfolio of research activities designed to address EM's needs without overlapping work being done elsewhere. An additional purpose is to enhance and maintain the technical capabilities and research infrastructure at the INEEL. This is a progress report for fiscal year 1998 for the five CCTE research investment areas: (a) transport aspects of selective mass transport agents, (b) chemistry of environmental surfaces, (c) materials dynamics, (d) characterization science, and (e) computational simulation of mechanical and chemical systems. In addition to the five purely technical research areas, this report deals with the science and technology foundations element of the CCTE from the standpoint of program management and complex-wide issues. This report also provides details of ongoing and future work in all six areas.

A Tool for Measuring NASA's Aeronautics Research Progress Toward Planned Strategic Community Outcomes

Science.gov (United States)

Tahmasebi, Farhad; Pearce, Robert

2016-01-01

Description of a tool for portfolio analysis of NASA's Aeronautics research progress toward planned community strategic Outcomes is presented. For efficiency and speed, the tool takes advantage of a function developed in Excels Visual Basic for Applications. The strategic planning process for determining the community Outcomes is also briefly discussed. Stakeholder buy-in, partnership performance, progress of supporting Technical Challenges, and enablement forecast are used as the criteria for evaluating progress toward Outcomes. A few illustrative examples of using the tool are also presented.

Environment and Economic Growth. Is Technical Change the Key to Decoupling?

Energy Technology Data Exchange (ETDEWEB)

Galeotti, M. [Universita di Milano, Milan (Italy)

2003-09-01

The relationship between economic growth and pollution is very complex, depending upon a host of different factors. Thus the study of this phenomenon represents a challenging endeavor. While most economics papers begin with theory and support that theory with econometric evidence, the literature on Environmental Kuznets Curves has proceeded in the opposite direction: first developing an empirical observation about the world, and then attempting to supply appropriate theories. A number of papers have aimed at providing the theoretical underpinnings to the Environmental Kuznets Curve. Prominent here is the class of optimal growth models. These are usually studied from the point of view of the analytical conditions that must hold in order to obtain an inverted-U functional relationship between pollution and growth. These models are however seldom confronted with the data. In this paper we take one popular optimal growth model designed for climate change policy analysis and carry out a few simulation exercises with the purpose of characterizing the relationship between economic growth and emissions. In particular, we try to assess the relative contribution of the ingredients of the well-known decomposition of the environment-growth relationship put forth by Grossman (1995): according to it, the presumed inverted-U pattern results from the joint effect of scale, composition, and technology components. We do this focusing on the developed regions of the world and on a global pollutant, CO2 emissions.

Nuclear structure theory. Technical progress report, September 1, 1982-August 31, 1984

International Nuclear Information System (INIS)

French, J.B.; Koltun, D.S.

1984-01-01

Research progress is reported. Spectral Averaging studies are outlined including the theory of level densities for interacting nucleons, the properties of single-particle nuclear excitations, spectral distributions for fixed symmetries, and applications to the secular behavior of fluctuation measures in complex nuclei. Collective States research is described, in particular the boson-fermion symmetries which are related to the U(5) limit of the interacting boson model. Nuclear Reaction studies are described including the statistical theory of pion absorption, direct reactions at intermediate energies, and the properties of the off-shell πN t-matrix. Progress is reported on the quark theory of nuclear matter and the construction of models for a Fermi fluid which, near the nuclear ground state, is a fluid of nucleons composed of quarks, and, at high densities or temperatures, is a quark fluid. Applications of formal scattering theory to the study of phase-conjugate optics are discussed. Publications are listed

Development of the Internet Library for the Second Progress Report on R and D for the geological disposal of HLW in Japan

International Nuclear Information System (INIS)

Shiotsuki, Masao; Ishikawa, Hirohisa

2000-01-01

This paper describes an Internet Library, the goal of which is to improve the quality assurance of the technical content of the Second Progress Report on R and D into the geological disposal of HLW in Japan. The Internet Library is used to centralize information management for the Second Progress Report. It uses a database system which stores a large quantity of technical memoranda and numeric data which provide the technical basis for the report. Members of the public and specialists are allowed access the data held on the system and may communicate their opinions and expert reviews, through the Internet. (author)

Office of Waste Isolation progress report, January 1978

International Nuclear Information System (INIS)

Zerby, C.D.

1978-01-01

This document, prepared to report progress on the National Waste Terminal Storage (NWTS) program, consists of project reports on work performed by organizations under subcontract to OWI, by DOE contractors, by OWI consultants, and by other federal agencies participating in the NWTS program. The project reports are made under the headings technical projects, facility projects, planning and analysis, and regulatory affairs

Office of Waste Isolation progress report, December 1977

International Nuclear Information System (INIS)

Zerby, C.D.

1976-01-01

This document reports progress on the OWI's portion of the National Waste Terminal Storage (NWTS) program. It comprises project reports on work performed by organizations under subcontract to OWI, by DOE contractors, by OWI consultants, and by other federal agencies participating in the NWTS program. They are made under the headings technical projects, facility projects, planning and analysis, and regulatory affairs

Office of Waste Isolation progress report, January 1978

Energy Technology Data Exchange (ETDEWEB)

Zerby, C.D.

1978-02-28

This document, prepared to report progress on the National Waste Terminal Storage (NWTS) program, consists of project reports on work performed by organizations under subcontract to OWI, by DOE contractors, by OWI consultants, and by other federal agencies participating in the NWTS program. The project reports are made under the headings technical projects, facility projects, planning and analysis, and regulatory affairs. (DLC)

Progress report of the Teilinstitut Nukleare Festkoerperphysik

International Nuclear Information System (INIS)

Heger, G.

1976-09-01

This progress report of the Teilinstitut Nukleare Festkoerperphysik covers the period from 1st June 1975 - 31st May 1976. The arrangement has been chosen to emphasis the main areas of research in which the institute is presently involved. These areas are Dynamics of Solids and Liquids, Electronic Structure and Magnetism of Solids and Development of Materials. Some of the technical developments relevant to these topics are also included. (orig.) [de

Methodology for plastic fracture - a progress report

International Nuclear Information System (INIS)

Wilkinson, J.P.D.; Smith, R.E.E.

1977-01-01

This paper describes the progress of a study to develop a methodology for plastic fracture. Such a fracture mechanics methodology, having application in the plastic region, is required to assess the margin of safety inherent in nuclear reactor pressure vessels. The initiation and growth of flaws in pressure vessels under overload conditions is distinguished by a number of unique features, such as large scale yielding, three-dimensional structural and flaw configurations, and failure instabilities that may be controlled by either toughness or plastic flow. In order to develop a broadly applicable methodology of plastic fracture, these features require the following analytical and experimental studies: development of criteria for crack initiation and growth under large scale yielding; the use of the finite element method to describe elastic-plastic behaviour of both the structure and the crack tip region; and extensive experimental studies on laboratory scale and large scale specimens, which attempt to reproduce the pertinent plastic flow and crack growth phenomena. This discussion centers on progress to date on the selection, through analysis and laboratory experiments, of viable criteria for crack initiation and growth during plastic fracture. (Auth.)

Project Progress Assessment Report (PPAR) 2015

International Nuclear Information System (INIS)

Sall, Baba

2015-01-01

This evaluation reports reviews basic information, output achievement, equipment and human resources, comment and recommendations. It highlights outputs Fully achieved, those which are partially achieved or in progress and also non achieved outputs. Regarding comments and lessons learned, counterpart stated that the overall timeline of the project is respected, even if activities are delayed to adapt to technical, financial and human resources constraints. The results obtained are in line with expectations thanks to a rigorously respected scientific approach. The Collegial Coordination of the project (DSV-LNERV-CIRAD) and the TO are in phase on the conduct of the Project the collection of baseline data is a crucial phase in the implementation of tsetse control programs. It makes it possible to implement a good strategy. The scientific and technical rigor and the good atmosphere within the Project team are also to be retained.

Project Progress Assessment Report (PPAR) 2012

International Nuclear Information System (INIS)

Sall, Baba

2012-01-01

This evaluation reports reviews basic information, output achievement, equipment and human resources, comment and recommendations. It highlights outputs Fully achieved, those which are partially achieved or in progress and also non achieved outputs. Regarding comments and lessons learned, counterpart stated that the overall timeline of the project is respected, even if activities are delayed to adapt to technical, financial and human resources constraints. The results obtained are in line with expectations thanks to a rigorously respected scientific approach. The Collegial Coordination of the project (DSV-LNERV-CIRAD) and the TO are in phase on the conduct of the Project the collection of baseline data is a crucial phase in the implementation of tsetse control programs. It makes it possible to implement a good strategy. The scientific and technical rigor and the good atmosphere within the Project team are also to be retained.

International Standards Development for Marine and Hydrokinetic Renewable Energy - Final Report on Technical Status

Energy Technology Data Exchange (ETDEWEB)

Rondorf, Neil E.; Busch, Jason; Kimball, Richard

2011-10-29

This report summarizes the progress toward development of International Standards for Marine and Hydrokinetic Renewable Energy, as funded by the U.S. Department of Energy (DOE) under the International Electrotechnical Commission (IEC) Technical Committee 114. The project has three main objectives: 1. Provide funding to support participation of key U.S. industry technical experts in 6 (originally 4) international working groups and/or project teams (the primary standards-making committees) and to attend technical meetings to ensure greater U.S. involvement in the development of these standards. 2. Provide a report to DOE and industry stakeholders summarizing the IEC standards development process for marine and hydrokinetic renewable energy, new international standards and their justifications, and provide standards guidance to industry members. 3. Provide a semi-annual (web-based) newsletter to the marine renewable energy community. The newsletter will educate industry members and stakeholders about the processes, progress, and needs of the US efforts to support the international standards development effort. The newsletter is available at www.TC114.us

Trastuzumab beyond progression in human epidermal growth factor receptor 2-positive advanced breast cancer: a german breast group 26/breast international group 03-05 study

DEFF Research Database (Denmark)

von Minckwitz, Gunter; du Bois, Andreas; Schmidt, Marcus

2009-01-01

PURPOSE: Trastuzumab shows clinical activity in human epidermal growth factor receptor 2 (HER-2)-positive early and advanced breast cancer. In the German Breast Group 26/Breast International Group 03-05 trial, we investigated if trastuzumab treatment should be continued beyond progression. METHODS......: Patients with HER-2-positive breast cancer that progresses during treatment with trastuzumab were randomly assigned to receive capecitabine (2,500 mg/m(2) body-surface area on days 1 through 14 [1,250 mg/m(2) semi-daily]) alone or with continuation of trastuzumab (6 mg/kg body weight) in 3-week cycles....... The primary end point was time to progression. RESULTS: We randomly assigned 78 patients to capecitabine and 78 patients to capecitabine plus trastuzumab. Sixty-five events and 38 deaths in the capecitabine group and 62 events and 33 deaths in the capecitabine-plus-trastuzumab group occurred during 15...

Energy budgets of animals: behavioral and ecological implications. Progress report

Energy Technology Data Exchange (ETDEWEB)

Porter, W.P.

1977-06-01

Progress is reported on the following studies: growth and reproduction of lizards; temperature and soil moisture requirements for egg hatching; metabolism measurements of developing eggs; factors controlling growth rate; longevity studies of lizards; growth and reproduction of deer mice with different levels of food and water deprivation; and critical densities of spines of cactus. (HLW)

Accelerator research studies: Technical progress report, June 1, 1988--May 31, 1989

International Nuclear Information System (INIS)

1989-01-01

This report discusses research progress in the following general topics: Study of transport and longitudinal compression of intense, high-brightness beams; study of collective ion acceleration by intense electron beams and pulse powered plasma focus; and study of microwave sources and parameter scaling for high-frequency electron-positron supercollider linacs

Growth and progression of colorectal cancer

International Nuclear Information System (INIS)

Yamada, T.; Ushio, K.; Hirota, T.

1988-01-01

There is an increasing interest in the natural history of colorectal carcinoma, now that small polypoid lesions of the large intestine can be detected effectively by radiology and endoscopy. The problems of this histo- and morphogenesis of colorectal cancer have, however, remained unsettled because the observation of the sequential change of a lesion with time by follow-up radiology and/or endoscopy is impossible once its malignancy is proved. Clinically the retrospective review of radiographic findings in overlooked cases is the only means to evaluate the natural history of colorectal cancer. This paper attempts to estimate the growth rate of colorectal cancer, based on a retrospective review of radiographic findings of overlooked cases, and analyses of the radiographic features of small polypoid lesions which may develop into advanced cancers

Technical progress report, October 1, 1980-September 30, 1981

International Nuclear Information System (INIS)

1981-01-01

Progress during the 12-month period, October 1, 1980 to September 30, 1981 on the University of Wisconsin Plasma Physics contract is described. Most of the work centers around two major experimental devices, the Levitated Octupole and Tokapole II. A major upgrade of the Octupole is underway to include 2 MW of ICRH and 1.8 MW of neutral beam heating. Meanwhile, gun optimization and low field operation has resulted in the attainment of 35% beta, a factor of 9 above the single fluid ballooning limit. The ICRH experiment is well underway, and the first neutral beam source has been installed. The Tokapole is operating reliably at the full design field of 10 kG with 12 msec discharges. Low q (approx. 0.4) discharges with flat current profiles are obtained at reduced (approx. 3kG) toroidal field. The device is presently being used to study shear Alfven wave heating, ECRH startup, poloidal ohmic heating, and plasma transport

NASA/DOD Aerospace Knowledge Diffusion Research Project. Paper 66: Emerging Trends in the Globalization of Knowledge: The Role of the Technical Report in Aerospace Research and Development

Science.gov (United States)

Pinelli,Thomas E.; Golich, Vicki L.

1997-01-01

Economists, management theorists, business strategists, and governments alike recognize knowledge as the single most important resource in today's global economy. Because of its relationship to technological progress and economic growth, many governments have taken a keen interest in knowledge; specifically its production, transfer, and use. This paper focuses on the technical report as a product for disseminating the results of aerospace research and development (R&D) and its use and importance to aerospace engineers and scientists. The emergence of knowledge as an intellectual asset, its relationship to innovation, and its importance in a global economy provides the context for the paper. The relationships between government and knowledge and government and innovation are used to place knowledge within the context of publicly-funded R&D. Data, including the reader preferences of NASA technical reports, are derived from the NASA/DoD Aerospace Knowledge Diffusion Research Project, a ten-year study of knowledge diffusion in the U.S. aerospace industry.

ESTIMATION OF THE MODERN STATE OF PROVISION OF AGRICULTURAL ENTERPRISES IN MYKOLAIV REGION BY MATERIAL AND TECHNICAL RESOURCES

Directory of Open Access Journals (Sweden)

Natalya Potryvaieva

2017-09-01

, the search for prospective ways of its renewal is urgent. In particular, the authors proposed to intensify the formation of the secondary market of restored agricultural machinery based on the experience of foreign countries. Progressive improvement of material and technical resources is seen in the development of a network of local leasing funds and funds of preferential lending to agricultural commodity producers; expansion of cooperative forms of acquisition and exploitation of high-tech; the growth of dealer centres that provide rural commodity producers with equipment on leasing terms. In the conclusions, it is proved that the reduction of the number of the main types of equipment at agricultural enterprises in Mykolaiv region led to the fact that most of the technics are used longer the normative lifetime, on-load for each type of equipment is constantly increasing due to its scarcity. Improvement of the efficiency and growth of agricultural production and the level of its intensification needs updating of the material and technical base of agricultural enterprises, which requires significant investments. Taking into account the implementation of the region targeted programs, the role of public authorities is to develop measures aimed at a comprehensive solution to problems related not only to the implementation of technical, investment, and innovation policies but also to the coordinated co-operation between the industrial, commercial, and financial strategy.

Productivity Measurement Of Technical Institute

Directory of Open Access Journals (Sweden)

Miss.Pooja Yadav

2015-05-01

Full Text Available Abstract The increasing concern over globalization between other things has made the achievement of lifetime skills vital for all classes of people. Achievement of such skills can be developed from technical education programs in the advance of any nation. Skill gaining provides knowledge and inculcates the approaches that are essential for arrival and progress into an occupation. When skills are developed in any occupation it will provide and improve the standard of living with the cover beside poverty thereby behind national development. This paper observes sampling distribution and moving average concept that how technical education can generate the required skills the significance of skill acquisition its roles benefits and sustainability in national development. It also mentions among others that government should look into and improve productivity that can encourage skill achievement for the youths. The solutions are divided the sampling box into few group before stacking up workstation and use table and some other wood product. Cost reduction for each solution was intended and the solution with highest cost decrease is chosen to increase the productivity of the college.

Measures of Student Growth

Science.gov (United States)

Texas Education Agency, 2016

2016-01-01

Beginning in the 2017-2018 school year, appraisal systems in Texas, whether the state-recommended system or a locally developed system, will need to include a measure of student growth at the individual teacher level. Student growth measures how much a student progresses academically during his or her time with a particular teacher. It takes into…

Technical Co-operation Report for 1996. Report by the Director General

International Nuclear Information System (INIS)

1997-01-01

The Agency's Technical Cooperation (TC) Programme made further progress during 1996 in implementing recent initiatives to strengthen efficiency and effectiveness. These initiatives seek to maximize the developmental contribution of counterpart institutions by emphasizing the management of technology to solve social and economic problems. The new direction has been embodied in the term ''Partners in Development''. The Partners in Development approach is reflected in last year's Report to the Board of Governors and the General Conference on Strengthening of the Agency's Technical Co-operation Activities, which provided an update on ongoing activities and elaborated new initiatives. The 1995 Technical Cooperation Report focused on the progress in implementing these initiatives. Next year, the Secretariat plans to combine the TC Report with the Report on Strengthening of the Agency's Technical Co-operation Activities in order to improve the clarity, consistency and economy of these presentations. Establishing a development partnership with Member States is the central goal of a new Strategy for TC. The refinement of this strategy required considerable effort during 1996, when the process first began to define objectives, targets and the means of accomplishing them. Alongside internal consultations, the role of SAGTAC became instrumental in reaching consensus on the main elements of the strategy. Future efforts include the formulation of implementation plans for the strategy. Once completed, the strategy will be presented to the TACC and Board in 1997. Reflecting these developments, section A of this Report presents the basic features of the TC Strategy, and the approach to be taken to achieve its objectives. The Strategy addresses among others the recommendations contained in resolution GC(40)/RES/13 on the Strengthening of Technical Co-operation: activities to improve the scientific and technological capabilities of developing countries; to achieve sustainable

The 1989 progress report: Polytechnic school laboratories' Direction

International Nuclear Information System (INIS)

1989-01-01

The 1989 progress report of the laboratories' Direction of the Polytechnic School (France) is presented. The research activities carried out in each laboratory are summarized. Scientific and technical cooperation, financial and employement aspects are included. The main fields of research are: biochemistry, chemistry, reaction mechanisms, organic synthesis, mechanics of solids, meteorology, irradiated solids, optics, physics, biophysics, lasers, mathematics, econometrics, epistemology, management and computer science [fr

Office of Waste Isolation progress report, December 1977

Energy Technology Data Exchange (ETDEWEB)

Zerby, C.D.

1976-01-31

This document reports progress on the OWI's portion of the National Waste Terminal Storage (NWTS) program. It comprises project reports on work performed by organizations under subcontract to OWI, by DOE contractors, by OWI consultants, and by other federal agencies participating in the NWTS program. They are made under the headings technical projects, facility projects, planning and analysis, and regulatory affairs. (DLC)

Growth stratal records of instantaneous and progressive limb rotation in the Precordillera thrust belt and Bermejo basin, Argentina

Science.gov (United States)

Zapata, TomáS. R.; Allmendinger, Richard W.

1996-10-01

Analysis of synorogenic deposits preserved near the thrust front zone of the Precordillera fold and thrust belt and in the Bermejo foreland basin in central Argentina documents the evolution of deformation during the last 5 Myr as well as the thrust system kinematics. Seismic lines across the area display examples of progressive and instantaneous limb rotations. The easternmost thrust plate of the Central Precordillera, the Niquivil thrust, experienced episodic motion in two main stages: a first thrust movement as a fault-propagation fold and a second movement as a high-angle anticlinal breakthrough fault after a period of quiescence. Growth strata deposited in the La Pareja intermontane basin and the Las Salinas and Bermejo anticline recorded continuous growth of Eastern Precordilleran structures beginning at ˜2.7 Ma, with uplift rates of ˜0.3 mm/yr for the Niquivil anticline, 1.08 mm/yr for the Las Salinas anticline, and between ˜0.6 and 0.38 mm/yr during the last ˜2 Myr for the Bermejo anticline. Once the Eastern Precordillera began to grow, the propagation of the Niquivil thrust stopped, restricting the deformation to the young Vallecito out-of sequence thrust. The complex geometry of growth strata deposited on the back limb of the Las Salinas anticline can be explained by using a model of a two-step fault propagation fold with constant layer thickness. The Bermejo anticline of the Eastern Precordillera is formed by the simultaneous propagation of a shallow fault, responsible for the fold shape, and a deep fault that produced vertical uplift. A growth triangle that documents instantaneous forelimb rotation for a fault-propagation fold is recorded for the first time in a published seismic line.

A New-Growth Perspective on Non-Renewable Resources

DEFF Research Database (Denmark)

Groth, Christian

This article reviews issues related to the incorporation of non-renewable resources in the theory of economic growth and development. As an offshoot of the new growth theory of the last two decades a series of contributions have studied endogenous technical change in relation to resource scarcity...

The impact of the endogenous technical change on climate policies

International Nuclear Information System (INIS)

Sassi, O.

2008-11-01

This research aims at revisiting the 'autonomous vs. induced' debate on the costs of climate policies, first by broadening the framework of the technical change induction to other economical sectors, and then by attempting to go beyond the concept of technical change induction and think in terms of a structural change induction. After a review of modes of representation of the technical progress in economical prospective models for the assessment of climate policies, the author presents the IMACLIM-R model, a recursive general equilibrium model which simulates the evolution of the world economy within 12 regions and 12 sectors between 2001 and 2100. The results obtained with this model are then presented and discussed, in the case of a reference scenario which displays a significant change towards a carbon-intensive path. These results stress the risks related to a 'laissez faire' attitude. The author explores the consequences in terms of climate policies with a more or less extended taking into account of phenomena of induction of technical and structural changes

Technical progress, the concept of individualized cancer treatment and the innovation of computer-assisted radiotherapy planning

International Nuclear Information System (INIS)

Merkle, K.; Tanneberger, S.; Matschke, S.

1985-01-01

After a first step of cancerogenesis, the further development of the tumor is an individual process. At the end of this process the tumor is formed as an individual in the individual. The individuality of cancer exists on the level of organs, tissues and cells and includes an individual tumor-host relationship. Today, optimized cancer treatment requires a most precise biological characterization possible of the tumor and of the tumor-host relationship, which will provide objective information about the individual character of every tumor. Routine analysis and strict therapeutic consideration of the clinical and biological individuality of human cancer can offer real chances for the improvement of cancer treatment. A routine acquisition of individual tumor characteristics will be possible only if methods and equipment are available for the registration of suitable parameters. In this context technical innovations have an essential influence on the realization of the concept of individualized cancer treatment. With the method of flow cytophotometry and other techniques examples are given in how far the ideas of individual cancer management can be realized by introduction of new technical solutions into medical research and clinical practice. Unfortunately there is still a lack of methodology in individualizing cancer treatment. The individualization of radiotherapy is connected to an extremely high degree of technical innovations. Particularly this refers to the topometrical description of the target volume in relation to the adjacent anatomical structures and the body contour as well as the fitting of isodoses to the shape and size of the target volume. As an example of innovation of a technical solution for individual radiotherapy planning the computer-assisted radiotherapy planning system DOPSY is described. (author)

Downcast Enrollments: A Desperate Need of Holistic Marketing for Technical Education

OpenAIRE

Mahajan, Prashant; Golahit, Suresh

2017-01-01

International audience; Purpose: Modern history has shown that only those countries, which could acquire capability to develop and apply science and technology, have found great success to grow their wealth and improve living conditions of their population. Technical education in India contributes a major share to the overall education system and plays a vital role in the social and economic development of the nation. There is a rapid growth of technical education in last decade in terms of t...

Growth and dynamics of scale invariant matter. Progress report and continuation request

International Nuclear Information System (INIS)

Savit, R.; Sander, L.M.

1986-01-01

Research concentrates on the growth of crystals. Solutions are sought for problems in growth velocity and the modeling of nonequilibrium and disorderly irreversible growth. A list of publications resulting from this work is included

Power system technical performance issues related to the application of long HVAC cables

DEFF Research Database (Denmark)

Wiechowski, on behalf of Cigre WG C4.502, W.; Sluis, L. V. der; Ohno, Teruo

2011-01-01

This paper reports the progress of work of Cigre Working Group C4.502 “Power system technical performance issues related to the application of long HVAC cables”. The primary goal of the WG C4.502 is to write a technical brochure that will serve as practical guide for performing studies necessary...... for assessing the technical performance of HV/EHV systems with large share of AC cable lines. This paper besides providing a background for formulation of WG C4.502 and its overall aim, describes the tasks that were accomplished before the interim report was submitted to Study Committee C4 System Technical...... Performance in August 2010. The work in the WG is ongoing and final report will be ready according to the time schedule in 2012. The focus of this paper is in particular to show all issues related to system technical performance with assigned weights in terms of their importance and/or uniqueness for cable...

A technical solution to a difficult problem - An update

International Nuclear Information System (INIS)

Asselstine, J.K.

1985-01-01

A goal of the Reduced Enrichment Research and Test Reactor Program (RERTR) established by the U.S. Department of Energy is to develop the technical means needed to utilize LEU instead of HEU fuels in research and test reactors and to do so without operational penalties and without affecting safety characteristics. This goal has been pursued now for seven years in cooperation with many of you who are participants in this conference. The program has made significant progress in the development, demonstration and application of new LEU research reactor fuels. According to recent projections, the percentage of HEU fuel in international commerce which is technically replaceable with LEU fuels has been growing steadily as research continues. There appears to be no technical barrier to eventual replacement of HEU fuel with LEU fuel in research and test reactors. While there are many politically complex and technically difficult issues involved in nonproliferation, I conclude that the use of highly enriched weapons grade uranium as a fuel in civilian research reactors stands out as one problem which has a straight forward technical solution. The technical solution is the effort you in the RERTR program are embarked on. Once that solution is in hand, the operators of research reactors are urged to take political and legal initiatives to make the conversion happen. By effecting this conversion they will help minimize the trade in highly enriched uranium and make the world a little safer

A technical solution to a difficult problem - An update

Energy Technology Data Exchange (ETDEWEB)

Asselstine, J K

1985-07-01

A goal of the Reduced Enrichment Research and Test Reactor Program (RERTR) established by the U.S. Department of Energy is to develop the technical means needed to utilize LEU instead of HEU fuels in research and test reactors and to do so without operational penalties and without affecting safety characteristics. This goal has been pursued now for seven years in cooperation with many of you who are participants in this conference. The program has made significant progress in the development, demonstration and application of new LEU research reactor fuels. According to recent projections, the percentage of HEU fuel in international commerce which is technically replaceable with LEU fuels has been growing steadily as research continues. There appears to be no technical barrier to eventual replacement of HEU fuel with LEU fuel in research and test reactors. While there are many politically complex and technically difficult issues involved in nonproliferation, I conclude that the use of highly enriched weapons grade uranium as a fuel in civilian research reactors stands out as one problem which has a straight forward technical solution. The technical solution is the effort you in the RERTR program are embarked on. Once that solution is in hand, the operators of research reactors are urged to take political and legal initiatives to make the conversion happen. By effecting this conversion they will help minimize the trade in highly enriched uranium and make the world a little safer.

Progress report No. 2 on the Scientific Investigation Program for the Nevada Yucca Mountain Site, October 1, 1989--March 31, 1990

International Nuclear Information System (INIS)

1990-01-01

In accordance with the requirements of Section 113(b)(3) of the Nuclear Waste Policy Act of 1982 (Pub. L. No. 97-425), as amended, the US Department of Energy (DOE) has prepared this report on the progress of scientific investigation activities at Yucca Mountain in southern Nevada for October 1, 1989, through March 31, 1990. This report is the second of a series of reports that are issued at intervals of approximately six months during the period of scientific investigation. The progress report presents short summaries of the status of scientific investigation activities and cites technical reports and research products that provide more detailed information on the activities. The report provides highlights of work started during the reporting period, work in progress, and work completed and documented during the reporting period. In addition, the report is the vehicle for discussing major changes, if any, to the DOE's scientific investigation program. The progress report conveys information in a convenient summary form to be used for informational purposes only. It is not intended to be the mechanism for controlling and documenting technical or policy positions regarding changes in schedules or the technical program. Such changes are controlled through rigorous DOE change-control procedures. The progress report only describes such approval changes. 49 refs., 3 tabs

Nuclear-waste management semiannual progress report, April 1982-September 1982

International Nuclear Information System (INIS)

Chikalla, T.D.; Powell, J.A.

1982-12-01

This document is one of a series of technical progress reports designed to report on radioactive waste management programs at Pacific Northwest Laboratory. Accomplishments in the following programs are reported: waste treatment; nuclear waste Materials Characterization Center (MCC); airborne waste management; low-level waste management; waste isolation; remedial actions; and supporting studies

Growth versus the environment - Is there a trade-off?

Energy Technology Data Exchange (ETDEWEB)

Kaageson, P

1997-04-01

The intensity of energy and materials use in OECD countries is diminishing over time despite falling metal and energy prices. Material demand is sometimes falling in absolute terms, but there are also a few examples of rapid growth. The supply of fossil fuels and minerals is being exhausted, in some cases at a rapid speed, but the question addressed here is whether the rate of depletion is so fast that there will be no time for technical progress to create adequate substitutes. Overall, this appears not to be the case. The two main industrial metals are very abundant, and most minor metals already have substitutes for many of their applications. A few metals can be expected to become very scarce, but much of the large quantities in use could be recycled. Developments in OECD Europe over the last 25 years have resulted in relative or absolute delinking between economic growth and environmental damage. On the other hand, it is uncertain whether continuing economic development along these lines will in all cases lead to the achievement of sustainable development, even over 25-30 years. Indeed, this study identifies some examples where slower GDP growth would have resulted in less damage (e.g. household waste and emissions of CO{sub 2} and NO{sub x}, and possibly the depletion of fish stocks and the negative impact of forestry and agriculture on biodiversity.) 500 refs

Technical progress review of extraction of uranium from fly ash

International Nuclear Information System (INIS)

Gao Renxi; Gao Junning; Wu Qingming; Chen Gang; Wan Hongjin; Zhang Ziyue

2014-01-01

The increasing of fly ash in coal-fired power plants at home and abroad year by year and the potential impacts to the environment attracted media attention. Although the extraction of uranium from the fly ash in coal-fired power plants had optional process from technique aspect and sufficient preliminary researches, but considering the low grade of the uranium in fly ash and particularity of the mineral composition, it is easy to have a high cost of extraction. As a consequence, it is not included in the development plan of uranium mining and metallurgy. The present applications of fly ash are only building materials, building roads and pit valley backfill, the resource utilization rate was low and was still in its early stages of development and application. In view of this, the research advances and the latest development trends of extraction of uranium from fly ash at home and abroad were introduced from the technical aspect, and the beneficial analyzes of the prospect and advices to this industry were given. (authors)

LMFBR flexible pipe joint development program. Annual technical progress report, government fiscal year 1977

International Nuclear Information System (INIS)

1978-01-01

Currently, the ASME Boiler and Pressure Vessel Code does not allow the use of flexible pipe joints (bellows) in Section III, Class 1 reactor primary piping systems. Studies have shown that the primary piping loops of LMFBR's could be simplified by using these joints. This simplification translates directly into shorter primary piping runs and reduced costs for the primary piping system. Further cost savings result through reduced vault sizes and reduced containment building diameter. In addition, the use of flexible joints localizes the motions from thermally-induced piping growth into components which are specifically designed to accommodate this motion. This reduces the stress levels in the piping system and its components. It is thus economically and structurally important that flexible piping joints be available to the LMFBR designer. The overall objective of the Flexible Joint Program is to provide this availability. This will be accomplished through the development of ASME rules which allow the appropriate use of such joints in Section III, Class 1 piping systems and through the development and demonstration of construction methods which satisfy these rules. The rule development includes analytic and testing methodology formulations which will be supported by subscale bellows testing. The construction development and demonstration encompass the design, fabrication, and in-sodium testing of prototypical LMFBR plant-size flexible pipe joints which meet all ASME rule requirements. The satisfactory completion of these developmental goals will result in an approved flexible pipe joint design for the LMFBR. Progress is summarized in the following efforts undertaken during 1977 to accomplish these goals: (1) code case support, (2) engineering and design, (3) material development, (4) testing, and (5) manufacturing development

Productivity growth patterns in US dairy products manufacturing plants

NARCIS (Netherlands)

Geylani, P.C.; Stefanou, S.E.

2011-01-01

We analyse the productivity growth patterns in the US dairy products industry using the Census Bureau's plant-level data set. We decompose Total Factor Productivity (TFP) growth into the scale and technical change components and analyse variability of plants' productivity by constructing transition

Technical efficiency and productivity of Chinese county hospitals: an exploratory study in Henan province, China.

Science.gov (United States)

Cheng, Zhaohui; Tao, Hongbing; Cai, Miao; Lin, Haifeng; Lin, Xiaojun; Shu, Qin; Zhang, Ru-Ning

2015-09-09

Chinese county hospitals have been excessively enlarging their scale during the healthcare reform since 2009. The purpose of this paper is to examine the technical efficiency and productivity of county hospitals during the reform process, and to determine whether, and how, efficiency is affected by various factors. 114 sample county hospitals were selected from Henan province, China, from 2010 to 2012. Data envelopment analysis was employed to estimate the technical and scale efficiency of sample hospitals. The Malmquist index was used to calculate productivity changes over time. Tobit regression was used to regress against 4 environmental factors and 5 institutional factors that affected the technical efficiency. (1) 112 (98.2%), 112 (98.2%) and 104 (91.2%) of the 114 sample hospitals ran inefficiently in 2010, 2011 and 2012, with average technical efficiency of 0.697, 0.748 and 0.790, respectively. (2) On average, during 2010-2012, productivity of sample county hospitals increased by 7.8%, which was produced by the progress in technical efficiency changes and technological changes of 0.9% and 6.8%, respectively. (3) Tobit regression analysis indicated that government subsidy, hospital size with above 618 beds and average length of stay assumed a negative sign with technical efficiency; bed occupancy rate, ratio of beds to nurses and ratio of nurses to physicians assumed a positive sign with technical efficiency. There was considerable space for technical efficiency improvement in Henan county hospitals. During 2010-2012, sample hospitals experienced productivity progress; however, the adverse change in pure technical efficiency should be emphasised. Moreover, according to the Tobit results, policy interventions that strictly supervise hospital bed scale, shorten the average length of stay and coordinate the proportion among physicians, nurses and beds, would benefit hospital efficiency. Published by the BMJ Publishing Group Limited. For permission to use (where

Experimental Program Final Technical Progress Report: 15 February 2007 to 30 September 2012

Energy Technology Data Exchange (ETDEWEB)

Kinney, Edward R. [University of Colorado, Boulder, CO

2014-09-12

This is the final technical report of the grant DE-FG02-04ER41301 to the University of Colorado at Boulder entitled "Intermediate Energy Nuclear Physics" and describes the results of our funded activities during the period 15 February 2007 to 30 September 2012. These activities were primarily carried out at Fermilab, RHIC, and the German lab DESY. Significant advances in these experiments were carried out by members of the Colorado group and are described in detail.

Simulating tumor growth in confined heterogeneous environments

International Nuclear Information System (INIS)

Gevertz, Jana L; Torquato, Salvatore; Gillies, George T

2008-01-01

The holy grail of computational tumor modeling is to develop a simulation tool that can be utilized in the clinic to predict neoplastic progression and propose individualized optimal treatment strategies. In order to develop such a predictive model, one must account for many of the complex processes involved in tumor growth. One interaction that has not been incorporated into computational models of neoplastic progression is the impact that organ-imposed physical confinement and heterogeneity have on tumor growth. For this reason, we have taken a cellular automaton algorithm that was originally designed to simulate spherically symmetric tumor growth and generalized the algorithm to incorporate the effects of tissue shape and structure. We show that models that do not account for organ/tissue geometry and topology lead to false conclusions about tumor spread, shape and size. The impact that confinement has on tumor growth is more pronounced when a neoplasm is growing close to, versus far from, the confining boundary. Thus, any clinical simulation tool of cancer progression must not only consider the shape and structure of the organ in which a tumor is growing, but must also consider the location of the tumor within the organ if it is to accurately predict neoplastic growth dynamics

Physics of correlated systems. Technical progress report, December 1996 - June 1999

International Nuclear Information System (INIS)

Greene, C.H.

1999-01-01

During the current funding period, which covers a period of approximately 2.5 years, the authors have tackled a number of challenging problems that involve nonperturbative particle-particle interactions in two qualitatively different areas: electron-electron interactions in photoionization and photodetachment, and atom-atom interactions in Bose-Einstein condensates. The following discusses the progress achieved in these different areas. The emphasis in this summary will concentrate on approximately the last year of research accomplishments, although the bibliography below includes all research publications that were supported during the time period of this grant

Technical Education in Pre and Post Independent India

Science.gov (United States)

Janardhana, G.; Rajasekhar, M.

2012-01-01

This paper deals with technical education growth, policies in pre and post independent India. The world is moving forward rapidly and positively, into an era where societies and economies are incrementally based on knowledge. The importance of nations in the 21st Century shall be judged not by their economic strength alone, but also by their power…

Radiology and the internet, basic principles and technical requirements

International Nuclear Information System (INIS)

Boegl, K.

2000-01-01

As a new communication media the Internet has revolutionized the global exchange of information which is one of the major sources of progress in medicine. This article reviews the history of the Internet's evolution and describes some fundamental technical concepts. The importance of Internet services for everyday professional work is examined with special consideration of radiology. Special emphasis is laid on the current technical limitations that have delayed a broad practical implementation of tele-medical applications. As a highly innovative medical speciality, radiology has always been at the forefront of research and development in the field of clinical Internet applications. By taking a look at recent innovations, the impact of the Internet on the radiologist's working environment of the future is highlighted. (orig.) [de

Technical report on the accelerators

Energy Technology Data Exchange (ETDEWEB)

Bex, L [ed.

1996-12-31

GANIL operation and the technical studies performed in 1994 are described. The milestones for 1994 are: SISSI (Source d`Ions Secondaires a Supraconducteurs Intense) has been in operation and used for secondary beam production with four different primary beams. The 100 kV platform for beam injection in the CO1 has been in operation for production of metallic beams which demand is increasing. Finally the SPIRAL project (Systeme de Production d`Ions Radioactifs Acceleres en Ligne) is in progress. In late 1994 the civil work has started in view of the installation of the machine in the north part of the GANIL machine building. (K.A.). 48 refs.

Technical report on the accelerators

International Nuclear Information System (INIS)

Bex, L.

1995-01-01

GANIL operation and the technical studies performed in 1994 are described. The milestones for 1994 are: SISSI (Source d'Ions Secondaires a Supraconducteurs Intense) has been in operation and used for secondary beam production with four different primary beams. The 100 kV platform for beam injection in the CO1 has been in operation for production of metallic beams which demand is increasing. Finally the SPIRAL project (Systeme de Production d'Ions Radioactifs Acceleres en Ligne) is in progress. In late 1994 the civil work has started in view of the installation of the machine in the north part of the GANIL machine building. (K.A.)

Review and comment on the advanced spent fuel management process (1): Technical aspects and non-proliferation concerns

International Nuclear Information System (INIS)

Song, Yo Taik

2001-01-01

Efforts are made to analyze the project, the Advanced Spent Fuel Management Technology (ASFMT), which is currently carried out at Korea Atomic Energy Research Institute, on the technical feasibility and validity as well as on the nuclear non-proliferation concerns. The project is a part of a program under the 'Long and Midterm Nuclear Development Program'. On the technical analysis, reviewed the papers presented at the national and international meetings on the subject by KAERI staffs, and also participated to various technical discussions on the 'Mock-up Test', currently in progress. On the non-proliferation concerns, the ASFMT project was reviewed and analyzed in reference to various programs currently in progress or in a formulation stages in US, such as the DOE TOPS and ATW. Further reviewed the past JASNEC process and programs for possible application of the ASFMT project for JASNEC project. Provided a few thoughts for effectively carrying out the ASFMT project, and a plan for the next phase is presented

Review and comment on the advanced spent fuel management process (1): Technical aspects and non-proliferation concerns

Energy Technology Data Exchange (ETDEWEB)

Song, Yo Taik

2001-01-01

Efforts are made to analyze the project, the Advanced Spent Fuel Management Technology (ASFMT), which is currently carried out at Korea Atomic Energy Research Institute, on the technical feasibility and validity as well as on the nuclear non-proliferation concerns. The project is a part of a program under the 'Long and Midterm Nuclear Development Program'. On the technical analysis, reviewed the papers presented at the national and international meetings on the subject by KAERI staffs, and also participated to various technical discussions on the 'Mock-up Test', currently in progress. On the non-proliferation concerns, the ASFMT project was reviewed and analyzed in reference to various programs currently in progress or in a formulation stages in US, such as the DOE TOPS and ATW. Further reviewed the past JASNEC process and programs for possible application of the ASFMT project for JASNEC project. Provided a few thoughts for effectively carrying out the ASFMT project, and a plan for the next phase is presented.

The Development of CBM Vocabulary Measures: Grade 5. Technical Report #1212

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 7. Technical Report #1214

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 6. Technical Report # 1213

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 3. Technical Report #1210

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 4. Technical Report #1211

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 8. Technical Report #1215

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

The Development of CBM Vocabulary Measures: Grade 2. Technical Report #1209

Science.gov (United States)

Alonzo, Julie; Anderson, Daniel; Park, Bitnara Jasmine; Tindal, Gerald

2012-01-01

In this technical report, we describe the development and piloting of a series of vocabulary assessments intended for use with students in grades two through eight. These measures, available as part of easyCBM[TM], an online progress monitoring and benchmark/screening assessment system, were developed in 2010 and administered to approximately 1200…

Progress report of the Teilinstitut Nukleare Festkoerperphysik

International Nuclear Information System (INIS)

Geerk, J.; Linker, G.

1977-10-01

This progress report of the Teilinstitut Nukleare Festkoerperphysik covers the period from June 1sup(st), 1976 - May 31sup(st), 1977. The arrangement has been chosen to emphasize the main research areas the institute is presently involved. These areas are the Dynamics of Solids and Liquids, the Electronic Structure and Magnetism of Solids, and the Development and Investigation of New Materials. Some of the technical developments relevant to these topics are also included. (orig.) [de

A theory of economic growth with material/energy resources and dematerialization. Interaction of three growth mechanisms

Energy Technology Data Exchange (ETDEWEB)

Ayres, Robert U. [Department of Physical Resource Theory, Chalmers Institute, Gothenburg (Sweden); Van den Bergh, Jeroen C.J.M. [Department of Spatial Economics, Faculty of Economics and Business Administration, and Institute for Environmental Studies, Free University, De Boelelaan 1105, Amsterdam 1081 HV (Netherlands)

2005-10-05

The nature of energy and material resources in a non-optimizing growth theory framework is clarified. This involves two modifications of the conventional theory. Firstly, multiple feedback mechanisms or 'growth engines' are identified, such that the impact of the cost of production through demand on growth is accounted for. Secondly, a production function distinguishes between resource use, technical efficiency, and value creation. The resulting model is analytically solved under the condition of a constant growth rate. Given model complexity, numerical experiments are performed as well, providing relevant insights to the academic and political debates on 'environmental Kuznets curves' and 'dematerialization.'.

Online Career and Technical Education in the Community College

Science.gov (United States)

Garza Mitchell, Regina L.

2017-01-01

Very little empirical research has been conducted about online career and technical education (CTE). Despite the continuing enrollment growth in online education (Lokken, 2016) and the national emphasis on CTE as a means of boosting the economy (D'Amico, Morgan, Katsinas, & Friedel, 2014), relatively little is understood about the scope and…

National Waste Terminal Storage Program. Progress report, October 1, 1976--September 30, 1977

International Nuclear Information System (INIS)

Asher, J.M.

1978-04-01

The National Waste Terminal Storage Program Report comprises five sections: technical projects, facility projects, planning and analysis, regulatory affairs, and public affairs. Progress made in these areas during the period October 1, 1976, to September 30, 1977, is reported

U.C. Davis high energy particle physics research: Technical progress report -- 1990

Energy Technology Data Exchange (ETDEWEB)

NONE

1990-12-31

Summaries of progress made for this period is given for each of the following areas: (1) Task A--Experiment, H1 detector at DESY; (2) Task C--Experiment, AMY detector at KEK; (3) Task D--Experiment, fixed target detectors at Fermilab; (4) Task F--Experiment, PEP detector at SLAC and pixel detector; (5) Task B--Theory, particle physics; and (6) Task E--Theory, particle physics.

The Relationship between Career Growth and Organizational Commitment

Science.gov (United States)

Weng, Qingxiong; McElroy, James C.; Morrow, Paula C.; Liu, Rongzhi

2010-01-01

This research examines the relationship between employees' career growth and organizational commitment. Career growth was conceptualized by four factors: career goal progress, professional ability development, promotion speed and remuneration growth, while organizational commitment was conceptualized using Meyer and Allen's (1997) three component…

Divisional progress reports for period 1 July 1982 to 30 June 1983

International Nuclear Information System (INIS)

1984-09-01

This progress report deals with technical and research work done at the AAEC Research establishment for the period 1 July 1982 to 30 June 1983. Work done in the following divisions is reported: Applied Mathematics and Computing, Applied Physics, Environmental Science, Isotope, Materials, Nuclear Technology

METHOD IMPROVEMENT FOR DETERMINING THE TECHNICAL LEVEL OF CIVIL AIRCRAFT

Directory of Open Access Journals (Sweden)

2016-01-01

Full Text Available Aircraft are high-tech engineering products which are characterized by a wide range of properties including the two most important groups that respectively characterize the efficiency and technical level.Improving the aircraft efficiency is an essential factor for air transport development, but the efficiency can not be fully describe the technical system, especially in forecasting and new technology requirements development. Aircraft de- signer must evaluate the prospects of a technical solution, but it’s not always possible to calculate the efficiency accuratelyat the design stage. The operator should be able to choose the most technically-advanced aircraft available in the market inorder not to let it grow obsolete quickly. This determines the need for non-economic evaluation of technical systems that can be done by assessment of their technical level.The technical level is a general index that includes a set of technical perfection indicators. Technical perfection is reflected in terms of material and energy intensity, in terms of ergonomics, safety, etc. and is achieved as a result of origi- nal design solutions, the use of new high-strength low-density materials, the introduction of advanced technological pro-cesses, calculation methods, verification, testing, etc.There is a tight connection between the product properties and its weight, because weight is the material reflection of these properties. Therefore, improvement of the product properties usually leads to an intense increase of its weight. To deal with this phenomenon is only possible with widely using scientific and technical progress results. In accordance with this, the technical perfection can be interpreted as a major component of quality that is created without the weight increase. This approach requires investment in research and testing new technical solutions.The method was developed to determine the technical level of civil long-haul aircraft which has been modified to

Accessing key steps of human tumor progression in vivo by using an avian embryo model

Science.gov (United States)

Hagedorn, Martin; Javerzat, Sophie; Gilges, Delphine; Meyre, Aurélie; de Lafarge, Benjamin; Eichmann, Anne; Bikfalvi, Andreas

2005-02-01

Experimental in vivo tumor models are essential for comprehending the dynamic process of human cancer progression, identifying therapeutic targets, and evaluating antitumor drugs. However, current rodent models are limited by high costs, long experimental duration, variability, restricted accessibility to the tumor, and major ethical concerns. To avoid these shortcomings, we investigated whether tumor growth on the chick chorio-allantoic membrane after human glioblastoma cell grafting would replicate characteristics of the human disease. Avascular tumors consistently formed within 2 days, then progressed through vascular endothelial growth factor receptor 2-dependent angiogenesis, associated with hemorrhage, necrosis, and peritumoral edema. Blocking of vascular endothelial growth factor receptor 2 and platelet-derived growth factor receptor signaling pathways by using small-molecule receptor tyrosine kinase inhibitors abrogated tumor development. Gene regulation during the angiogenic switch was analyzed by oligonucleotide microarrays. Defined sample selection for gene profiling permitted identification of regulated genes whose functions are associated mainly with tumor vascularization and growth. Furthermore, expression of known tumor progression genes identified in the screen (IL-6 and cysteine-rich angiogenic inducer 61) as well as potential regulators (lumican and F-box-only 6) follow similar patterns in patient glioma. The model reliably simulates key features of human glioma growth in a few days and thus could considerably increase the speed and efficacy of research on human tumor progression and preclinical drug screening. angiogenesis | animal model alternatives | glioblastoma

A new semiquantitative method for evaluation of metastasis progression.

Science.gov (United States)

Volarevic, A; Ljujic, B; Volarevic, V; Milovanovic, M; Kanjevac, T; Lukic, A; Arsenijevic, N

2012-01-01

Although recent technical advancements are directed toward developing novel assays and methods for detection of micro and macro metastasis, there are still no reports of reliable, simple to use imaging software that could be used for the detection and quantification of metastasis in tissue sections. We herein report a new semiquantitative method for evaluation of metastasis progression in a well established 4T1 orthotopic mouse model of breast cancer metastasis. The new semiquantitative method presented here was implemented by using the Autodesk AutoCAD 2012 program, a computer-aided design program used primarily for preparing technical drawings in 2 dimensions. By using the Autodesk AutoCAD 2012 software- aided graphical evaluation we managed to detect each metastatic lesion and we precisely calculated the average percentage of lung and liver tissue parenchyma with metastasis in 4T1 tumor-bearing mice. The data were highly specific and relevant to descriptive histological analysis, confirming reliability and accuracy of the AutoCAD 2012 software as new method for quantification of metastatic lesions. The new semiquantitative method using AutoCAD 2012 software provides a novel approach for the estimation of metastatic progression in histological tissue sections.

Challenges of technical cooperation in the petroleum industry

International Nuclear Information System (INIS)

Al-Athel, S.A.

1992-01-01

The need and prospects for international technical cooperation in the petroleum industry are reviewed. Since it directly affects the survival of the inhabitants of the planet, environmental protection is a field that could enjoy maximum international cooperation; oil spills, product environmental hazards, waste minimization and disposal and oil field fires are the main areas identified. Technical cooperation in other areas of the industry, namely exploration, production, oil field development, refining and petrochemicals, may involve some controversy. Attention is drawn to the conflicting interests of multinational companies, who almost completely control the technology of these activities, and host developing countries. It is advocated that arrangements involving technology transfer should make provision for the growth of indigenous technology. (UK)

Advanced light source: Compendium of user abstracts and technical reports,1993-1996

Energy Technology Data Exchange (ETDEWEB)

None, None

1997-04-01

This compendium contains abstracts written by users summarizing research completed or in progress from 1993-1996, ALS technical reports describing ongoing efforts related to improvement in machine operations and research and development projects, and information on ALS beamlines planned through 1998. Two tables of contents organize the user abstracts by beamline and by area of research, and an author index makes abstracts accessible by author and by principal investigator. Technical details for each beamline including whom to contact for additional information can be found in the beamline information section. Separate abstracts have been indexed into the database for contributions to this compendium.

Circulating serum interleukin-6, serum chitinase-3-like protein-1, and plasma vascular endothelial growth factor are not predictive for remission and radiographic progression in patients with early rheumatoid arthritis

DEFF Research Database (Denmark)

Brahe, C H; Dehlendorff, C; Østergaard, M

2018-01-01

OBJECTIVE: To investigate serum interleukin-6 (IL-6), serum chitinase-3-like protein-1 (YKL-40), and plasma vascular endothelial growth factor (VEGF) as measures of disease activity and predictors of clinical remission and radiographic progression in two early rheumatoid arthritis (RA) randomized...

Technical challenges of superconductivity and cryogenics in pursuing TESLA-TTF

International Nuclear Information System (INIS)

Shu, Quan-Sheng

1996-01-01

TESLA (TeV Energy Superconducting Linear Accelerator) Collaboration is an international R ampersand D effort towards the development of an e + e - linear collider with 500 GeV center of mass by means of 20 km active superconducting accelerating structures at a frequency of 1.3 GHz. The ultimate challenges faced by the TESLA project are (1) to raise operational accelerating gradients to 25 MV/m from current world level of 5-10 MV/m, and (2) to reduce construction costs (cryomodules, klystrons, etc.) down to $2,000/MV from now about $40,000/MV. The TESLA Collaboration is building a prototype TESLA test facility (TTF) of a 500 MeV superconducting linear accelerator to establish the technical basis. TTF is presently under construction and will be commissioned at DESY in 1997, through the joint efforts of 24 laboratories from 8 countries. Significant progress has been made in reaching the high accelerating gradient of 25 MV/m in superconducting cavities, developing cryomodules and constructing TTF infrastructure, etc. This paper will briefly discuss the challenges being faced and review the progress achieved in the technical area of superconductivity and cryogenics by the TESLA Collaboration

Los Alamos National Laboratory Environmental Restoration Project quarterly technical report, April--June 1994

Energy Technology Data Exchange (ETDEWEB)

1994-08-18

This quarterly report describes the technical status of activities in the Los Alamos National Laboratory Environmental Restoration (ER) Project. Each activity is identified by an activity data sheet number, a brief title describing the activity or the technical area where the activity is located, and the name of the project leader. The Hazardous and Solid Waste Amendments (HSWA) portion of the facility operating permit requires the submission of a technical progress report on a quarterly basis. This report, submitted to fulfill the permit`s requirement, summarizes the work performed and the results of sampling and analysis in the ER Project. Suspect waste found include: Radionuclides, high explosives, metals, solvents and organics. The data provided in this report have not been validated. These data are considered ``reviewed data.``

DELUSIONS OF PROGRESS: A Case For Reconceptualising ...

African Journals Online (AJOL)

A Case For Reconceptualising Environmental Education ... assuming that economic growth and technological progress are ways to a cleaner environment ... overseas teachers came. ... this experience are several: that students .... humanity, but in an African context, they .... cross-cultural connections that recognise this.

AFR spent fuel storage program. Technical progress report, January 1981-March 1981

International Nuclear Information System (INIS)

1981-01-01

Work on this project is focused on developing design and licensing information for the model facility. Deliverables were submitted to DOE for facility modification, security design, and licensing documentation. Work is essentially complete on the high-density rack design with deliverable planned for April 30, 1981. A continuing program for completion of design and licensing information development was initiated by AGNS in February 1981. Progress to date is satisfactory

Savannah River Plant Works Technical Department monthly progress report for May 1958: Deleted Version

Energy Technology Data Exchange (ETDEWEB)

1958-06-17

This progress report by the Atomic Energy Division of the Savannah River Plant covers: Reactor Technology; Separation Technology; Engineering Assistance; Health Physics; and General Laboratory Work. (JT)

Recent progress on borophene: Growth and structures

Science.gov (United States)

Kong, Longjuan; Wu, Kehui; Chen, Lan

2018-06-01

Boron is the neighbor of carbon on the periodic table and exhibits unusual physical characteristics derived from electron-deficient, highly delocalized covalent bonds. As the nearest neighbor of carbon, boron is in many ways similar to carbon, such as having a short covalent radius and the flexibility to adopt sp 2 hybridization. Hence, boron could be capable of forming monolayer structural analogues of graphene. Although many theoretical papers have reported finding two-dimensional allotropes of boron, there had been no experimental evidence for such atom-thin boron nanostructures until 2016. Recently, the successful synthesis of single-layer boron (referred to as borophene) on the Ag(111) substrate opens the era of boron nanostructures. In this brief review, we will discuss the progress that has been made on borophene in terms of synthetic techniques, characterizations and the atomic models. However, borophene is just in infancy; more efforts are expected to be made in future on the controlled synthesis of quality samples and tailoring its physical properties.

FY2011 Annual Progress Report for Advanced Combustion Engine Research and Development

Energy Technology Data Exchange (ETDEWEB)

none,

2011-12-01

Annual Progress Report for the Advanced Combustion Engine Research and Development (R&D) subprogram supporting the mission of the Vehicle Technologies Program by removing the critical technical barriers to commercialization of advanced internal combustion engines (ICEs) for passenger and commercial vehicles that meet future federal emissions regulations.

Progression from isolated growth hormone deficiency to combined pituitary hormone deficiency.

Science.gov (United States)

Cerbone, Manuela; Dattani, Mehul T

2017-12-01

Growth hormone deficiency (GHD) can present at any time of life from the neonatal period to adulthood, as a result of congenital or acquired insults. It can present as an isolated problem (IGHD) or in combination with other pituitary hormone deficiencies (CPHD). Pituitary deficits can evolve at any time from GHD diagnosis. The number, severity and timing of occurrence of additional endocrinopathies are highly variable. The risk of progression from IGHD to CPHD in children varies depending on the etiology (idiopathic vs organic). The highest risk is displayed by children with abnormalities in the Hypothalamo-Pituitary (H-P) region. Heterogeneous data have been reported on the type and timing of onset of additional pituitary hormone deficits, with TSH deficiency being most frequent and Diabetes Insipidus the least frequent additional deficit in the majority, but not all, of the studies. ACTH deficiency may gradually evolve at any time during follow-up in children or adults with childhood onset IGHD, particularly (but not only) in presence of H-P abnormalities and/or TSH deficiency. Hence there is a need in these patients for lifelong monitoring for ACTH deficiency. GH treatment unmasks central hypothyroidism mainly in patients with organic GHD, but all patients starting GH should have their thyroid function monitored closely. Main risk factors for development of CPHD include organic etiology, H-P abnormalities (in particular pituitary stalk abnormalities, empty sella and ectopic posterior pituitary), midline brain (corpus callosum) and optic nerves abnormalities, genetic defects and longer duration of follow-up. The current available evidence supports longstanding recommendations for the need, in all patients diagnosed with IGHD, of a careful and indefinite follow-up for additional pituitary hormone deficiencies. Copyright © 2017 Elsevier Ltd. All rights reserved.

1985. Progress annual report

International Nuclear Information System (INIS)

1986-06-01

Tore Supra construction has been vigorously continued. The whole cryogenic system has been entirely delivered. On TFR priority has been given to electron cyclotron resonance heating; but also neutral heating mechanisms, pellet injection, plasma-wall interaction in the presence of pumped limiter, impurity transport and plasma turbulence have been studied and progress on diagnostics have been made. On Petula, with lower hybrid wave, the numerous results on ion heating, current drive, plasma stability in the presence of non-inductive current and on Tore Supra technical problems are important. At last, theoretical and numerical results are concerned with plasma equilibrium macroscopic evolution of plasma, RF heating, plasma instabilities, magnetic islands, turbulence, transport coefficients and spectroscopy [fr

Fusion reactor materials. Semiannual progress report for period ending September 30, 1993

Energy Technology Data Exchange (ETDEWEB)

Rowcliffe, A.F.; Burn, G.L.; Knee`, S.S.; Dowker, C.L. [comps.

1994-02-01

This is the fifteenth in a series of semiannual technical progress reports on fusion reactor materials. This report combines research and development activities which were previously reported separately in the following progress reports: Alloy Development for Irradiation Performance; Damage Analysis and Fundamental Studies; Special purpose Materials. These activities are concerned principally with the effects of the neutronic and chemical environment on the properties and performance of reactor materials; together they form one element of the overall materials programs being conducted in support of the Magnetic Fusion Energy Program of the U.S. Department of Energy. The Fusion Reactor Materials Program is a national effort involving several national laboratories, universities, and industries. The purpose of this series of reports is to provide a working technical record for the use of the program participants, and to provide a means of communicating the efforts of materials scientists to the rest of the fusion community, both nationally and worldwide.

Review of the technical bases of 40 CFR Part 190.

Energy Technology Data Exchange (ETDEWEB)

Kelly, John E.; McMahon, Kevin A.; Siegel, Malcolm Dean; Weiner, Ruth F.; Bixler, Nathan E.; Klein, Keith A. (Longenecker and Associates)

2010-07-01

The dose limits for emissions from the nuclear fuel cycle were established by the Environmental Protection Agency in 40 CFR Part 190 in 1977. These limits were based on assumptions regarding the growth of nuclear power and the technical capabilities of decontamination systems as well as the then-current knowledge of atmospheric dispersion and the biological effects of ionizing radiation. In the more than thirty years since the adoption of the limits, much has changed with respect to the scale of nuclear energy deployment in the United States and the scientific knowledge associated with modeling health effects from radioactivity release. Sandia National Laboratories conducted a study to examine and understand the methodologies and technical bases of 40 CFR 190 and also to determine if the conclusions of the earlier work would be different today given the current projected growth of nuclear power and the advances in scientific understanding. This report documents the results of that work.

Pregnancy-induced increase in circulating IGF-I is associated with progression of diabetic retinopathy in women with type 1 diabetes

DEFF Research Database (Denmark)

Nielsen, Lene Ringholm; Vestgaard, Marianne; Laugesen, Caroline S

2011-01-01

To evaluate the influence of Insulin-like Growth factor-I (IGF-I) and Placental Growth Hormone (GH) on progression of diabetic retinopathy during pregnancy in women with type 1 diabetes.......To evaluate the influence of Insulin-like Growth factor-I (IGF-I) and Placental Growth Hormone (GH) on progression of diabetic retinopathy during pregnancy in women with type 1 diabetes....

FY2013 Energy Storage R&D Progress Report

Energy Technology Data Exchange (ETDEWEB)

none,

2014-02-01

The FY 2013 Progress Report for Energy Storage R&D focuses on advancing the development of batteries to enable a large market penetration of hybrid and electric vehicles. Program targets focus on overcoming technical barriers to enable market success including: (1) significantly reducing battery cost, (2) increasing battery performance (power, energy, durability), (3) reducing battery weight & volume, and (4) increasing battery tolerance to abusive conditions such as short circuit, overcharge, and crush.

Environmental Management Science Program awards. Fiscal year 1997 annual progress report

Energy Technology Data Exchange (ETDEWEB)

Simmons, A. [ed.; Benner, W.H.; DePaolo, D.J.; Faybishenko, B.; Majer, E.L.; Pallavicini, M.; Russo, R.E.; Shultz, P.G.; Wan, J.

1997-10-01

Lawrence Berkeley National Laboratory was awarded eight Environmental Management Science Program (EMSP) research grants in Fiscal Year 1996. This report summarizes the progress of each grant in addressing significant DOE site cleanup issues after completion of the first year of research. The technical progress made to date in each of the research projects is described in greater detail in individual progress reports. The focus of the research projects covers a diversity of areas relevant to site cleanup, including bioremediation, health effects, characterization, and mixed waste. Some of the projects cut across a number of focus areas. Three of the projects are directed toward characterization and monitoring at the Idaho National Engineering and Environmental Laboratory, as a test case for application to other sites.

Environmental Management Science Program awards. Fiscal year 1997 annual progress report

International Nuclear Information System (INIS)

Simmons, A.; Benner, W.H.; DePaolo, D.J.; Faybishenko, B.; Majer, E.L.; Pallavicini, M.; Russo, R.E.; Shultz, P.G.; Wan, J.

1997-10-01

Lawrence Berkeley National Laboratory was awarded eight Environmental Management Science Program (EMSP) research grants in Fiscal Year 1996. This report summarizes the progress of each grant in addressing significant DOE site cleanup issues after completion of the first year of research. The technical progress made to date in each of the research projects is described in greater detail in individual progress reports. The focus of the research projects covers a diversity of areas relevant to site cleanup, including bioremediation, health effects, characterization, and mixed waste. Some of the projects cut across a number of focus areas. Three of the projects are directed toward characterization and monitoring at the Idaho National Engineering and Environmental Laboratory, as a test case for application to other sites

Progress report 1998

International Nuclear Information System (INIS)

1999-01-01

The O.P.R.I. is in charge of environmental general surveillance and follow-up of natural exposures; To monitor the nuclear installations, it carries out samples campaigns. The technical follow-up of medical installations concerns it too. The workers radiation protection as well as the public protection are in its attributions. We find in particular, three sanitary studies: about the North Cotentin, (the question of excess of leukemia or not, and due or not to the facility of La hague) Nogent-sur-Marne (the case of a nursery school built on a old factory using radium), and the situation of populations living in French Polynesia, areas that have worried the public with alarmist announcements published in newspapers. All the results relative to the radiations measurements for 1998 appear in this progress report. (N.C.)

Technical change in US industry: A cross-industry analysis

Science.gov (United States)

Nelson, R. R. (Editor)

1981-01-01

The nature of the public policies which have influenced the pace and pattern of technical progress in a number of American industries is studied with the view of assessing the broad effects of these policies. The industries studied are agriculture, pharmaceuticals, semiconductors, computers, civil aircraft, automobiles and residential construction. The policies considered include research and development funding as well as government procurement, education, information dissemination, patent protection, licensing, regulations, and anti-trust policies.

Internet - Technical Developments and Applications 2

CERN Document Server

Tkacz, Ewaryst; Rostanski, Maciej

2012-01-01

The unusual direct progress of civilization in many fields concerning technical sciences is being observed in the period of last two decades. Experiencing extraordinary dynamics of the development of technological processes, particularly in ways of communicating, makes us believe that  the information society is coming into existence. Having the information in today’s world of changing attitudes and socio-economic conditions can be perceived as one of the most important advantages. The content of this book is divided into four parts: ·         Mathematical and technical fundamentals, ·         Information management systems and project management ·         Information security and business continuity management ·         Interdisciplinary problems This monograph has been prepared to contribute in a significant way to the success of implementing consequences of human imagination  into social life. The authors believe that this monograph will influence the further technol...

Poverty Reduction and Shared Prosperity in Moldova : Progress and Prospects

OpenAIRE

World Bank Group

2016-01-01

Moldova has experienced rapid economic growth in the past decade, which has been accompanied by reductions in poverty and good performance in shared prosperity. Nonetheless, Moldova remains one of the poorest countries in Europe and faces challenges in sustaining the progress. The challenges for progress include spatial and cross-group inequalities, particularly because of unequal access t...

Developing Technical Writing Skills in the Physical Chemistry Laboratory: A Progressive Approach Employing Peer Review

Science.gov (United States)

Gragson, Derek E.; Hagen, John P.

2010-01-01

Writing formal "journal-style" lab reports is often one of the requirements chemistry and biochemistry students encounter in the physical chemistry laboratory. Helping students improve their technical writing skills is the primary reason this type of writing is a requirement in the physical chemistry laboratory. Developing these skills is an…

An Online Approach to Teaching International Outsourcing in Technical Communication Classes

Science.gov (United States)

St. Amant, Kirk

2005-01-01

The growth of international online access has given rise to a new production method--international outsourcing--that has important implications for technical communication practices. Successful interactions within international outsourcing require individuals to understand how cultural factors could affect online interactions. Today's technical…

Clean Energy Progress Report

Energy Technology Data Exchange (ETDEWEB)

NONE

2011-07-01

For the past several years, the IEA and others have been calling for a clean energy revolution to achieve global energy security, economic growth and climate change goals. This report analyses for the first time progress in global clean energy technology deployment against the pathways that are needed to achieve these goals. It provides an overview of technology deployment status, key policy developments and public spending on RDD&D of clean energy technologies.

LFCM [liquid-fed ceramic melter] vitrification technology: Quarterly progress report, January--March 1987

International Nuclear Information System (INIS)

Brouns, R. A.; Allen, C. R.; Powell, J. A.

1988-05-01

This report is compiled by the Nuclear Waste Treatment Program and the Hanford Waste Vitrification Program at Pacific Northwest Laboratory to describe the progress in developing, testing, applying and documenting liquid-fed ceramic melter vitrification technology. Progress in the following technical subject areas during the second quarter of FY 1987 is discussed: melting process chemistry and glass development, feed preparation and transfer systems, melter systems, canister filling and handling systems, and process/product modeling. 23 refs., 14 figs., 10 tabs

Encouraging Enrolments by People's Influence; A desperate need for Technical Education Evolution

OpenAIRE

Mahajan, Prashant; Golahit, Suresh

2017-01-01

International audience; — There is a rapid growth of technical education in last decade in terms of the no. of institutes and intake capacity in India but with improper and non-directional development. As per AICTE reports, there is noticeable gap in between the actual no. of enrolments and intake capacity of these institutes. In the year 2015-16, 46% of seats were vacant in Technical Education in India. Segmentation and 'People' factor of service mix is very important aspects in education se...

The AECL study for an intense neutron - generator (technical details)

Energy Technology Data Exchange (ETDEWEB)

Bartholomew, G A; Tunnicliffe, P R

1966-07-01

The AECL study for an intense neutron-generator has been in progress for two years. Recently the scientific and technical details and the conceptual designs were compiled in a report supporting proposals addressed to AECL's Board of Directors for further work. The compilation is being issued in this form to permit further discussion of the technical aspects. However readers are asked to appreciate that it was written primarily for an AECL audience, and specifically that those chapters giving tentative information about costs, the rate of investment and similar items have been omitted or modified, many references have been made to interim internal reports in order to complete the local documentation, but these references do not imply that the reports themselves can be made generally available. (author)

The AECL study for an intense neutron - generator (technical details)

International Nuclear Information System (INIS)

Bartholomew, G.A.; Tunnicliffe, P.R.

1966-01-01

The AECL study for an intense neutron-generator has been in progress for two years. Recently the scientific and technical details and the conceptual designs were compiled in a report supporting proposals addressed to AECL's Board of Directors for further work. The compilation is being issued in this form to permit further discussion of the technical aspects. However readers are asked to appreciate that it was written primarily for an AECL audience, and specifically that those chapters giving tentative information about costs, the rate of investment and similar items have been omitted or modified, many references have been made to interim internal reports in order to complete the local documentation, but these references do not imply that the reports themselves can be made generally available. (author)

Budgeting For National Economic Consolidation And Progression ...

African Journals Online (AJOL)

The paper exemplifies genuine concern and empathy for the perceived unimpressive pace of growth and development of Nigeria\\'s national economy. The 2007 budget aptly directed at consolidation is crystallized as affording stakeholders the potent drive towards meaningful progression in national economic management ...

Employers' Perception of Graduates with Entry-Level Technical Skills from Construction Industry Programs in Ghana and Nigeria

Science.gov (United States)

Acheampong, Philip

2013-01-01

The purpose of this comparative study was to identify the technical skills and abilities needed by prospective employees of construction industries in Ghana and Nigeria. Potential employees were defined here as recent graduates of construction industry programs with entry-level technical skills. The continuous growth in and expansion of these two…

Research in elementary particle physics: Technical progress report, June 1, 1987-May 31, 1988

International Nuclear Information System (INIS)

Kirsch, L.E.; Schnitzer, H.J.; Abbott, L.F.; Bensinger, J.R.; Blocker, C.A.

1988-01-01

The main topics discussed in the progress report: electron/photon algorithm groups; W and Z analysis; heavy quark analysis; gas gain monitoring; database upgrade; CDF test beam studies; string theory; cosmology; and neutral networks

Technical progress report

International Nuclear Information System (INIS)

1982-01-01

This report summarizes the work carried out by personnel at the Nuclear Physics Laboratory of the University of Colorado from about August 1, 1981 to October 1, 1982, under contract with the Department of Energy. The intermediate energy studies summarized in this report were carried out at the meson physics facilities at Los Alamos (LAMPF), the cyclotron at Indiana University (IUCF), and the meson physics facilities at Vancouver (TRIUMF). This year, for the first time, intermediate energy experimental studies are being reported in separate documents from the low energy and theoretical nuclear physics efforts. Experimental studies are reported on pion-nucleus interactions, charge exchange reactions, nucleon transfer reactions, and apparatus development

Technical Progress Report

Energy Technology Data Exchange (ETDEWEB)

Paul D. Ronney

2004-08-26

An ignition source was constructed that is capable of producing a pulsed corona discharge for the purpose of igniting mixtures in a test chamber. The corona generator can also be used as the ignition source for one cylinder on a test engine. The first tests were performed in a cylindrical shaped chamber to study the characteristics of the corona and analyze various electrode geometries. Next a test chamber was constructed that closely represented the dimensions of the combustion chamber of the test engine at USC. Combustion tests were performed in this chamber and various electrode diameters and geometries were tested. Higher peak pressures and faster pressure rise times were realized consistently in all test chambers versus standard spark plug ignition. A test engine was purchased for the project that has two spark plug ports per cylinder to The data acquisition and control system hardware for the USC engine lab was updated with new equipment. New software was also developed to perform the engine control and data acquisition functions including cylinder pressure monitoring. A ceramic corona electrode has been designed that fits in the new test engine and is capable of withstanding the pressures and temperatures encountered inside the combustion chamber. The corona ignition system was tested on the engine and an increase in both peak pressure and IMEP were seen in the initial test. There are issues that must be addressed before on-engine testing can continue such as EMF interference from the corona generator and electrical insulation on portions of the piston and cylinder head to prevent arcing. The EMF issue can be solved with proper shielding and grounding and various ceramic coatings are being researched for electrical insulation.

Technical Progress Report

International Nuclear Information System (INIS)

Engelhardt, G.R.; MacDonald, D.D.

1999-01-01

During the past quartile (two month period) most attention has been concentrated on the problem of definition critical temperature at which ''wet'' corrosion first became operable. It has been shown that, in principle, ''wet'' corrosion processes can not be ignored for Yucca Mountain, even for initial times, when the temperature of the surface of containers is well above the boiling temperature of water for the prevailing conditions. This is because the surfaces are covered by highly hydrophilic oxides (e.g. Fe 2 O 3 , NiO, Cr 2 O 3 ) that will hydrate to the form of corresponding hydroxides, which are proton conductors, at least when in the ''wet'' condition. Because proton conduction and the presence of ''bound'' water are all that are required for the external environment to support metallic corrosion in either its general or localized form. Thus, the temperature of dehydration of the hydroxide, e.g. M(OH) 2 → MO + H 2 O(g), is a better criterion for the upper temperature limit for ''wet'' corrosion than is the boiling temperature of ''bulk'' water. During this first task, we have reviewed the existing thermodynamic data base for the dehydration of metal hydroxides and analytical expressions have been developed that allow the upper temperature limit to be estimated

Ethanol stimulates tumor progression and expression of vascular endothelial growth factor in chick embryos.

Science.gov (United States)

Gu, Jian-Wei; Bailey, Amelia Purser; Sartin, Amanda; Makey, Ian; Brady, Ann L

2005-01-15

The mechanisms by which alcohol consumption causes cancer have not been established due to a lack of experimental studies. A chick embryo chorioallantoic membrane (CAM) model that bore human fibrosarcoma (HT1080) was used to determine whether the administration of physiologically relevant doses of ethanol could stimulate tumor growth, angiogenesis, metastasis, and vascular endothelial growth factor (VEGF) expression in tumors. HT1080 cells were inoculated onto the "upper CAM" on Day 8, saline or ethanol was administrated at a dose of 0.25 g/kg per day on the CAM, and the tumors were harvested on Day 17. VEGF mRNA and protein were determined by Northern blot analysis and enzyme-linked immunosorbent assay. Intratumoral vascular volume density (IVVD) was determined by point counting on periodic acid-Schiff-stained sections. Intravasation of HT1080 cells was determined using human-Alu polymerase chain reaction analysis. The effects of ethanol on VEGF expression and cell proliferation were examined in cultured HT1080 cells. Ethanol treatment for 9 days caused a 2.2-fold increase in tumor volume (867 +/- 138 mm(3) vs. 402 +/- 28 mm(3)), a 2.1-fold increase in IVVD (0.021 +/- 0.004 mm(3)/mm(3) vs. 0.010 mm(3)/mm(3) +/- 0.002 mm(3)/mm(3)), and a significant increase in VEGF mRNA or protein expression in tumors compared with a group of control embryos (n = 6 embryos; P 8-fold in the intravasated HT1080 cells in the CAM group compared with the control group (n = 6 embryos; P < 0.01). Physiologically relevant levels of ethanol (10 mM and 20 mM) caused a dose-related increase in VEGF mRNA and protein expression in cultured HT1080 cells. The ethanol-HT1080-conditioned media increased the proliferation of endothelial cells, but not of HT1080 cells. The findings suggest that the induction of angiogenesis and VEGF expression by ethanol represents an important mechanism of cancer progression associated with alcoholic beverage consumption. (c) 2004 American Cancer Society.

Geothermal direct-heat utilization assistance. Quarterly project progress report, July 1996--September 1996. Federal Assistance Program

Energy Technology Data Exchange (ETDEWEB)

Lienau, P.

1996-11-01

This report summarizes geothermal technical assistance, R&D and technology transfer activities of the Geo-Heat Center at Oregon Institute of Technology for the fourth quarter of FY-96. It describes 152 contacts with parties during this period related to technical assistance with geothermal direct heat projects. Areas dealt with include geothermal heat pumps, space heating, greenhouses, aquaculture, equipment, economics and resources. Research activities are summarized on greenhouse peaking. Outreach activities include the publication of a geothermal direct use Bulletin, dissemination of information, geothermal library, technical papers and seminars, and progress monitor reports on geothermal resources and utilization.

Seizing the Future: How Ohio's Career-Technical Education Programs Fuse Academic Rigor and Real-World Experiences to Prepare Students for College and Careers

Science.gov (United States)

Guarino, Heidi; Yoder, Shaun

2015-01-01

"Seizing the Future: How Ohio's Career and Technical Education Programs Fuse Academic Rigor and Real-World Experiences to Prepare Students for College and Work," demonstrates Ohio's progress in developing strong policies for career and technical education (CTE) programs to promote rigor, including college- and career-ready graduation…

An approach to knowledge structuring for advanced phases of the Technical and Management Information System (TMIS)

Science.gov (United States)

Goranson, H. T.

1986-01-01

The Technical and Management Information System (TMIS) must employ on enlightened approach to its object structure, but basic issues in conceptual structuring remain to be resolved. Sirius outlines the necessary agenda and reports on progress toward solutions.

INDOT Technical Training Plan : [Technical Summary

Science.gov (United States)

2012-01-01

A wide range of job classifications, increasing technical : performance expectations, licensing and certification requirements, : budget restrictions and frequent department : reorganization has made technical training of employees : more difficult, ...

Progress report 2011-2013 - Brazilian Energy and Nuclear Research Institute - IPEN

International Nuclear Information System (INIS)

2014-01-01

This progress report presents the results of the R&D center of IPEN in accordance with the main programs: Lasers Technology, Applications of Ionizing Radiations, Biotechnology, Renewable Energies, Radiopharmacy, Nuclear Science and Technology, Environmental Science and Technology, Nuclear Reactors and Fuel Cycle, Materials and Nanotechnology, Nuclear Safety, Education, Brazilian Multipurpose Reactor and Scientific and Technical Production

Fusion materials semiannual progress report for period ending December 31, 1999

Energy Technology Data Exchange (ETDEWEB)

Burn, G.

2000-03-01

This is the twenty-seventh in a series of semiannual technical progress reports on fusion materials. This report combines the full spectrum of research and development activities on both metallic and non-metallic materials with primary emphasis on the effects of the neutronic and chemical environment on the properties and performance of materials for in-vessel components.

Fusion materials semiannual progress report for period ending December 31, 1999

International Nuclear Information System (INIS)

Burn, G.

2000-01-01

This is the twenty-seventh in a series of semiannual technical progress reports on fusion materials. This report combines the full spectrum of research and development activities on both metallic and non-metallic materials with primary emphasis on the effects of the neutronic and chemical environment on the properties and performance of materials for in-vessel components

Progress report 2008-2010 - Brazilian Energy and Nuclear Research Institute - IPEN

International Nuclear Information System (INIS)

2011-01-01

This progress report presents the results of the R and D center of IPEN in the areas of: Lasers Technology; Renewable Energies; Nuclear Reactors and Fuel Cycle; Applications of Ionizing Radiations; Nuclear Science and Technology; Materials and Nanotechnology; Environmental Science and Technology; Radiopharmacy; Nuclear Safety; and Education. Also presents the Technical and Scientific Production od the center

AECL's progress in DUPIC fuel development

International Nuclear Information System (INIS)

Sullivan, J.D.; Ryz, M.A.; Lee, J.W.

1997-01-01

Previous papers described progress in choosing a fabrication route for the DUPIC (Direct Use of Spent PWR Fuel in CANDU) fuel cycle [1], details of the OREOX (Oxidation Reduction of Oxide fuel) process, and preliminary results of out-cell and small-scale in-cell experiments [2]. AECL's project to develop the DUPIC fuel cycle has now progressed to the stage of fabricating DUPIC fuel elements for irradiation testing in a research reactor. Because of the high radiation fields around the spent PWR fuel, all work is being done in hot cells. The equipment used for fabrication of the DUPIC fuel elements is described in this paper. The commissioning, in-cell installation and current status of the fabrication process are also described and plans for the completion of this phase of the DUPIC project are outlined. The goal of this phase of the project is demonstration of the technical feasibility of the DUPIC fuel cycle. (author)

Overexpression of high molecular weight FGF-2 forms inhibits glioma growth by acting on cell-cycle progression and protein translation

International Nuclear Information System (INIS)

Lemiere, Sylvie; Azar, Rania; Belloc, Francis; Guersel, Demir; Pyronnet, Stephane; Bikfalvi, Andreas; Auguste, Patrick

2008-01-01

In order to clarify the role of HMW FGF-2 in glioma development and angiogenesis, we over-expressed different human FGF-2 isoforms in C6 rat glioma cell line using a tetracycline-regulated expression system. Phenotypic modifications were analyzed in vitro and compared to untransfected cells or to cells over-expressing 18 kDa FGF-2 or all FGF-2 isoforms. In particular, we demonstrate that HMW FGF-2 has unique features in inhibiting glioma cell proliferation. HMW FGF-2 expressing cells showed a cell-cycle arrest at the G2M, demonstrating a role of HMW FGF-2 in controlling the entry in mitosis. Moreover, hydroxyurea was ineffective in blocking cells at the G1S boundary when HMW FGF-2 was expressed. We also show that the HMW FGF-2 isoforms inhibit 4E-BP1 phosphorylation at critical sites restoring the translation inhibitory activity of 4E-BP1. In vivo, inhibition of tumor growth was observed when cells expressed HMW FGF-2. This indicates that HMW FGF-2 inhibits tumor growth in glioma cells by acting on cell-cycle progression and protein translation

Scientific and technical progress in high-energy astrophysics at INPE

International Nuclear Information System (INIS)

Bui-Van, N.A.; Jayanthi, U.B.; Jardim, J.O.D.; Braga, J.; Santo, C.M.E.

1984-01-01

The recent advances in high-energy Astrophysics pertains to the study of compact objects in galactic nuclei, binary systems and pulsars. These aspects are best understood by the study of the emissions in X- and gamma rays of these objects through the temporal variation in flux and spectrum. The Southern Hemisphere offers some of the unique objects for investigations such as galactic center, the Vela pulsar etc. For high temporal and spectra resolution studies two telescopes 'GeLi' and 'Pulsar' were designed and constructed. To support these scientific activities, a program in balloon launching and data acquisition facilities has been developed since 1971. The 'Balloon Launching Center' of INPE has capacity to launch balloons of -850,000 m 3 with payloads weighting about 1,000 Kg. Taking advantage of these facilities, project 'Bantar', with the goal to measure the atmospheric gamma-ray radiation in the Antartic Region, is under progress. (Author) [pt

Population Growth and Poverty in the Developing World.

Science.gov (United States)

Birdsall, Nancy

1980-01-01

The link between rapid population growth and the absolute poverty which currently afflicts 780 million people in developing countries (excluding China and other centrally planned economies) is examined. As a result of rapid population growth, many countries suffer slow per capita income growth, a lack of progress in reducing income inequality, and…

Do Farm Programs Explain Mean and Variance of Technical Efficiency? Stochastic Frontier Analysis

OpenAIRE

Ranjan, Rahul; Shaik, Saleem; Mishra, Ashok K.

2010-01-01

Past literature has examined the importance of farm programs on the volatility and returns on general and agriculture economic growth. The objective of this study was to assess the impact of farm program payments on technical efficiency. The study used aggregate state level panel data from the U.S agricultural sector. Results indicate production increasing with increasing units of inputs. Results from this study indicate that farm program payments play an important role in technical efficienc...

Research in elementary particle physics. Technical progress report, June 1, 1983-May 31, 1984

International Nuclear Information System (INIS)