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Sample records for growth sexual development

  1. Growth response, sexual development, carcass and meat quality of ...

    African Journals Online (AJOL)

    Effects of intratesticularly administered zinc tannate (ZT) on growth performance, sexual development, slaughter, carcass and meat quality characteristics of young bull calves (-225 kg, 7 months old) were investigated. Comparisons were made across a three (treatments: ZT animals, intact bulls and burdizzo-castrated.

  2. Androgens during development in a bird species with extremely sexually dimorphic growth, the brown songlark, Cinclorhamphus cruralis

    NARCIS (Netherlands)

    Isaksson, C.; Magrath, M. J. L.; Groothuis, T. G. G.; Komdeur, J.

    2010-01-01

    In birds, early exposure to androgens has been shown to influence offspring growth and begging behaviour, and has been proposed as a mechanism for the development of sexual size dimorphism (SSD). Sex specific effects during development can occur due to sex-specific allocation of maternal androgens,

  3. Burden of non-sexually transmitted infections on adolescent growth and development in the developing world.

    Science.gov (United States)

    Di Pentima, Cecilia

    2009-12-01

    A vast majority of children living in developing countries face their teen years following a childhood of malnutrition and limited access to education and health care. In this environment of disadvantages, exposure to old and reemerging infections become a significant determinant of their likelihood to overcome poverty: tuberculosis and its rapid progression during adolescence may anticipate a premature death; malaria, as well as its debilitating recurrent febrile episodes and anemia, is responsible for most of their lost time at school or work. Furthermore, the burden of anemia and malnutrition is aggravated by infestation with common intestinal worms such as with hookworms, Trichuris trichiura and Ascaris lumbricoides. These parasites compete for iron and nutrients and produce mucosal damage and inflammation causing anorexia and worsening the intake and absorption of their marginal diets. Other infections among the many neglected tropical infectious diseases, many others common to adolescents in developed countries, and some that could be controlled by access to vaccines, add scores against the physical and intellectual fitness of millions of teens in tropical developing countries.

  4. Dissecting the function of the different chitin synthases in vegetative growth and sexual development in Neurospora crassa.

    Science.gov (United States)

    Fajardo-Somera, Rosa A; Jöhnk, Bastian; Bayram, Özgür; Valerius, Oliver; Braus, Gerhard H; Riquelme, Meritxell

    2015-02-01

    Chitin, one of the most important carbohydrates of the fungal cell wall, is synthesized by chitin synthases (CHS). Seven sequences encoding CHSs have been identified in the genome of Neurospora crassa. Previously, CHS-1, -3 and -6 were found at the Spitzenkörper(Spk) core and developing septa. We investigated the functional importance of each CHS in growth and development of N. crassa. The cellular distribution of each CHS tagged with fluorescent proteins and the impact of corresponding gene deletions on vegetative growth and sexual development were compared. CHS-2, -4, -5 and -7 were also found at the core of the Spk and in forming septa in vegetative hyphae. As the septum ring developed, CHS-2-GFP remained at the growing edge of the septum until it localized around the septal pore. In addition, all CHSs were located in cross-walls of conidiophores. A partial co-localization of CHS-1-m and CHS-5-GFP or CHS-2-GFP occurred in the Spk and septa. Analyses of deletion mutants suggested that CHS-6 has a role primarily in hyphal extension and ascospore formation, CHS-5 in aerial hyphae, conidia and ascospore formation, CHS-3 in perithecia development and CHS-7 in all of the aforementioned. We show that chs-7/csmB fulfills a sexual function and chs-6/chsG fulfills a vegetative growth function in N. crassa but not in Aspergillus nidulans, whereas vice versa chs-2/chsA fulfills a sexual function in A. nidulans but not in N. crassa. This suggests that different classes of CHSs can fulfill distinct developmental functions in various fungi. Immunoprecipitation followed by mass spectrometry of CHS-1-GFP, CHS-4-GFP and CHS-5-GFP identified distinct putative interacting proteins for each CHS. Collectively, our results suggest that there are distinct populations of chitosomes, each carrying specific CHSs, with particular roles during different developmental stages. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Growth and sexual development of Etawah-cross kids from does of different levels of milk production

    Directory of Open Access Journals (Sweden)

    I-Ketut Sutama

    1999-06-01

    Full Text Available The experiment was conducted to evaluate growth and sexual development of female Etawah-cross kids of the progeny of the does with low (Group L, medium (Group M and high (Group H milk production. The does were fed King grass (Pennisetum purpureophoides (about 2% DM of liveweight and 400 g/head of concentrate. The amount of concentrate was increased to 600 g/head during the last two months of pregnancy period and during lactation. Kids were weaned at four months of age. Thereafter, they were reared in group and were fed King grass and concentrate. The animals were weighed every two weeks. A mature vasectomized buck were joined in each group to detect the onset of first oestrus (puberty. When kids reached puberty and had a liveweight of about 20 kg, they were mated with intact buck. Ovulation rate, progesterone profiles and fertility were observed. The results showed that pre-weaning growth rates of kids in all three groups were not significantly different (67.0 vs 74.9 vs 70.5 g/day, P>0.05. At six and 12 months of ages, Groups L and M had almost the same liveweight which were higher than Group H. Consequently, Groups L and M reached puberty about 3 - 6 weeks earlier than Group H. The average liveweight at puberty was 19.9, 18.2 and 18.8 kg for Groups L, M and H, respectively, or at about 57.1-69.8% (average 63.2% of mature liveweight. The pregnancy rate following first mating was relatively high (67-73% and all does were pregnant in the following mating. Average ovulation rate at conception were low (1.1 in all groups. It was concluded that differences in milk production of the does did not significantly affect post-weaning growth and sexual development and performances of kids. Other factors at certain age or growth phases might be more important to affect growth and reproduction of Etawah-cross goat, and this may warrant further study.

  6. Female adolescent sexuality. Promoting healthy sexual development.

    Science.gov (United States)

    Blythe, M J; Rosenthal, S L

    2000-03-01

    Health care providers must recognize the specific challenges and rewards of providing services for adolescents. Quality care begins with the establishment of trust, respect, and confidentiality between the health care provider and the adolescent. Data suggest that the normal age for beginning puberty is decreasing, which has important clinical, educational, and social implications. The health care provider should be aware of the broad range of potential sexual behaviors involving adolescents, as well as the teen's acceptance of such behaviors, often dictated by age, gender, culture, and education. When providing gynecologic care to adolescent girls, the physician should not only provide contraception and screen for sexually transmitted diseases but should contribute to the development of the patient's sexual health. Especially when providing care for the younger teen, the health care provider must focus on involving a member of the family or another significant adult to provide needed support and guidance. Anticipatory guidance for parents should focus on assessing their parenting styles and promoting supervision. Although parents should strive to maintain open communication with their adolescents, they may not accurately estimate the sexual activity of and the sexual risk for their teenage children. Parents need to be encouraged to consider the implications of their own sexual behaviors. The provider should attempt to foster a comfortable environment in which youth may seek help and support for appropriate medical care while reserving the right to disclose their sexual identity when ready. Health care professionals cannot exclude heterosexual behavior on the basis that a young woman self-identifies as homosexual. Her reported sexual behaviors may not indicate her sexual orientation. Self-definition of sexual orientation is a dynamic process including factors such as fantasies, desires, and behaviors. Self-definition of sexual identity is affected by individual

  7. Growth Data - Characterization of Sexual Growth Dimorphism in Sablefish

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sexual growth dimorphism (SGD) is a common phenomenon in nature. Numerous marine fishes exhibit SGD, with females often growing faster and attaining larger sizes...

  8. Sexual dimorphism in the growth of the cranium.

    Science.gov (United States)

    Baughan, B; Demirjian, A

    1978-09-01

    The major sexual dimorphisms in body size appear at puberty but, by then, 95% of the growth of the cranium is completed. As sexual dimorphism in the cranium is as great as for other parts of the body, this suggests that it must appear at an earlier age, and that cranium/body size ratios for the two sexes will vary during growth. Results from a longitudinal study of Montreal children are used to investigate this phenomenon. The effect is expressed quantitatively by proportional growth and growth velocity curves, based on the final size of boys, which show that the dimorphism indeed makes an early appearance. The data are also analyzed on an age scale relative to the ages of peak growth velocity in stature, derived from the individual growth curves. This shows that although there is a minor pubertal spurt in growth for the external cranial dimensions of boys, it contributes relatively little to the final dimorphism in cranial size. To summarize this aspect of growth, an index of cephalization is calculated: head length X head width/stature. Cross-sectional standards for the change of the mean index with age show a linear decline for boys and girls until puberty, with a constant difference between them. After puberty, the index becomes equal in the two sexes. Individual development curves for the index are however not linear.

  9. Effect of supplementation of Sesbania sesban on post-weaning growth performance and sexual development of Menz sheep (Ethiopia)

    NARCIS (Netherlands)

    Mekoya, A.; Oosting, S.J.; Fernandez-Rivera, S.; Tamminga, S.; Tegegne, A.; Zijpp, van der A.J.

    2009-01-01

    Most supplementation experiments with fodder trees including S. sesban have been of short duration and focused mainly on feed intake and growth rate. Long-term studies regarding the effects of feeding S. sesban on reproductive performance of sheep particularly in both sexes are scanty. This study

  10. Signaling governed by G proteins and cAMP is crucial for growth, secondary metabolism and sexual development in Fusarium fujikuroi.

    Directory of Open Access Journals (Sweden)

    Lena Studt

    Full Text Available The plant-pathogenic fungus Fusarium fujikuroi is a notorious rice pathogen causing hyper-elongation of infected plants due to the production of gibberellic acids (GAs. In addition to GAs, F. fujikuroi produces a wide range of other secondary metabolites, such as fusarins, fusaric acid or the red polyketides bikaverins and fusarubins. The recent availability of the fungal genome sequence for this species has revealed the potential of many more putative secondary metabolite gene clusters whose products remain to be identified. However, the complex regulation of secondary metabolism is far from being understood. Here we studied the impact of the heterotrimeric G protein and the cAMP-mediated signaling network, including the regulatory subunits of the cAMP-dependent protein kinase (PKA, to study their effect on colony morphology, sexual development and regulation of bikaverins, fusarubins and GAs. We demonstrated that fusarubin biosynthesis is negatively regulated by at least two Gα subunits, FfG1 and FfG3, which both function as stimulators of the adenylyl cyclase FfAC. Surprisingly, the primary downstream target of the adenylyl cyclase, the PKA, is not involved in the regulation of fusarubins, suggesting that additional, yet unidentified, cAMP-binding protein(s exist. In contrast, bikaverin biosynthesis is significantly reduced in ffg1 and ffg3 deletion mutants and positively regulated by FfAC and FfPKA1, while GA biosynthesis depends on the active FfAC and FfPKA2 in an FfG1- and FfG3-independent manner. In addition, we provide evidence that G Protein-mediated/cAMP signaling is important for growth in F. fujikuroi because deletion of ffg3, ffac and ffpka1 resulted in impaired growth on minimal and rich media. Finally, sexual crosses of ffg1 mutants showed the importance of a functional FfG1 protein for development of perithecia in the mating strain that carries the MAT1-1 idiomorph.

  11. Sexual scripts and sexual risk behaviors among Black heterosexual men: development of the Sexual Scripts Scale.

    Science.gov (United States)

    Bowleg, Lisa; Burkholder, Gary J; Noar, Seth M; Teti, Michelle; Malebranche, David J; Tschann, Jeanne M

    2015-04-01

    Sexual scripts are widely shared gender and culture-specific guides for sexual behavior with important implications for HIV prevention. Although several qualitative studies document how sexual scripts may influence sexual risk behaviors, quantitative investigations of sexual scripts in the context of sexual risk are rare. This mixed methods study involved the qualitative development and quantitative testing of the Sexual Scripts Scale (SSS). Study 1 included qualitative semi-structured interviews with 30 Black heterosexual men about sexual experiences with main and casual sex partners to develop the SSS. Study 2 included a quantitative test of the SSS with 526 predominantly low-income Black heterosexual men. A factor analysis of the SSS resulted in a 34-item, seven-factor solution that explained 68% of the variance. The subscales and coefficient alphas were: Romantic Intimacy Scripts (α = .86), Condom Scripts (α = .82), Alcohol Scripts (α = .83), Sexual Initiation Scripts (α = .79), Media Sexual Socialization Scripts (α = .84), Marijuana Scripts (α = .85), and Sexual Experimentation Scripts (α = .84). Among men who reported a main partner (n = 401), higher Alcohol Scripts, Media Sexual Socialization Scripts, and Marijuana Scripts scores, and lower Condom Scripts scores were related to more sexual risk behavior. Among men who reported at least one casual partner (n = 238), higher Romantic Intimacy Scripts, Sexual Initiation Scripts, and Media Sexual Socialization Scripts, and lower Condom Scripts scores were related to higher sexual risk. The SSS may have considerable utility for future research on Black heterosexual men's HIV risk.

  12. Toddler Growth and Development

    Science.gov (United States)

    ... time, his or her physical growth and motor development will slow, but you can expect to see ... Schedule of Well-Child Care Visits . ​​ Toddler Growth & Development Physical Skills Walks alone Pulls toys behind when ...

  13. Sexual Anxiety and Eroticism Predict the Development of Sexual Problems in Youth With a History of Sexual Abuse

    Science.gov (United States)

    Simon, Valerie A.; Feiring, Candice

    2017-01-01

    Youth with confirmed histories of sexual abuse (N = 118) were followed longitudinally to examine associations between their initial sexual reactions to abuse and subsequent sexual functioning. Participants were interviewed at abuse discovery (ages 8 through 15) and again 1 and 6 years later. Eroticism and sexual anxiety emerged as distinct indices of abuse-specific sexual reactions and predicted subsequent sexual functioning. Eroticism was associated with indicators of heightened sexuality, including more sexual risk behavior and views of sexual intimacy focused on partners’ needs. Sexual anxiety was associated with indicators of diminished sexuality, including few sexual partners and avoidant views of sexual intimacy. Age at abuse discovery moderated some associations, suggesting that the timing of abuse-specific reactions affects trajectories of sexual development. Findings point to the need for a developmental approach to understanding how abuse-specific sexual reactions disrupt sexual development and the need for early interventions promoting healthy sexual development. PMID:18408212

  14. [Population Growth and Development].

    Science.gov (United States)

    Clausen, A. W.

    Rapid population growth as a central development problem, the proper domain of government in reducing population growth, and effective measures which can be taken to reduce fertility are examined. Rapid population growth puts a brake on development because it exacerbates the difficult choice between higher consumption now and the investment needed…

  15. Sexual development of prepubertal children.

    NARCIS (Netherlands)

    Graaf, H. de; Rademakers, J.

    2006-01-01

    Studies of childhood sexuality are scarce and often focus on sexual abuse. In this review, an attempt is made to establish what is known, from empirical studies, about sexual behaviors (solitary and interpersonal) and feelings in pre-pubertal boys and girls. In addition, the research methods used

  16. A skeletochronological study of growth, longevity, and age at sexual ...

    Indian Academy of Sciences (India)

    Unknown

    Longevity and age at sexual maturity in an Italian population of Rana latastei were studied by skeletochrono- ... [Guarino F M, Lunardi S, Carlomagno M and Mazzotti S 2003 A skeletochronological study of growth, longevity, and age at sexual maturity in a ..... (Italian Ministry for Higher Education, and Scientific and.

  17. Fish Culture Data - Characterization of Sexual Growth Dimorphism in Sablefish

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sexual growth dimorphism (SGD) is a common phenomenon in nature. Numerous marine fishes exhibit SGD, with females often growing faster and attaining larger sizes...

  18. Physiology Data - Characterization of Sexual Growth Dimorphism in Sablefish

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sexual growth dimorphism (SGD) is a common phenomenon in nature. Numerous marine fishes exhibit SGD, with females often growing faster and attaining larger sizes...

  19. Normal growth and development

    Science.gov (United States)

    A child's growth and development can be divided into four periods: Infancy Preschool years Middle childhood years Adolescence Soon after birth, an infant normally loses about 5% to 10% of their birth weight. By about age ...

  20. Buffer or Brake? The Role of Sexuality-Specific Parenting in Adolescents' Sexualized Media Consumption and Sexual Development.

    Science.gov (United States)

    Overbeek, Geertjan; van de Bongardt, Daphne; Baams, Laura

    2018-03-13

    One main source of sexual socialization lies within family interactions. Especially sexuality-specific parenting may determine adolescents' sexual development-adolescents' sexual behavior and sexual risk behavior, sexualized media consumption and permissive sexual attitudes-to a significant extent, but different ideas exist about how this works. In this longitudinal study, we examined two hypotheses on how sexuality-specific parenting-parenting aimed specifically at children's sexual attitudes and behaviors-relates to adolescents' sexual development. A first buffer hypothesis states that parents' instructive media discussions with their children-called instructive mediation-buffers the effect of sexualized media consumption on adolescents' sexual attitudes and behavior and, vice versa, the effect of adolescents' sexual attitudes and behavior on sexualized media consumption. A second brake hypothesis states that parents, by communicating love-and-respect oriented sexual norms, slow down adolescents' development toward increased sexualized media use, permissive sexual attitudes, and sexual behavior and sexual risk behavior. Using four-wave longitudinal data from 514 Dutch adolescents aged 13-16 years (49.8% female), we found evidence to support a brake effect. More frequent parental communication of love-and-respect oriented sexual norms was associated with less permissive sexual attitudes and, for boys, with less advanced sexual behavior and a less rapid increase in sexual risk behavior. Parents' instructive mediation regarding adolescents' sexualized media consumption was associated with less permissive sexual attitudes at baseline, but only for girls. No systematic evidence emerged for a buffer effect of parents' instructive mediation. In conclusion, although our data seem to suggest that parent-child communication about sex is oftentimes "after the fact", we also find that more directive parental communication that conveys love-and-respect oriented sexual norms

  1. Trace minerals in human growth and development.

    Science.gov (United States)

    Castillo-Durán, C; Cassorla, F

    1999-01-01

    Trace mineral deficiencies may affect several biological functions in humans, including physical growth, psychomotor development and immunity. We have reviewed the mechanisms whereby several trace mineral deficiencies may affect these biological functions at different ages (fetal life, infancy, childhood and adolescence), as well as the evidence supporting this association. We describe the effects of zinc deficiency on the hormonal regulation of growth and sexual development in both humans and animal models. We provide data regarding the effects of iron deficiency on growth and psychomotor development. We mention the effects of copper, manganese, selenium and iodine deficiencies on growth and development. We conclude that iron deficiency may affect psychomotor development, but does not appear to affect growth. Zinc deficiency may cause growth retardation and psychomotor delay.

  2. FigA, a putative homolog of low-affinity calcium system member Fig1 in Saccharomyces cerevisiae, is involved in growth and asexual and sexual development in Aspergillus nidulans.

    Science.gov (United States)

    Zhang, Shizhu; Zheng, Hailin; Long, Nanbiao; Carbó, Natalia; Chen, Peiying; Aguilar, Pablo S; Lu, Ling

    2014-02-01

    Calcium-mediated signaling pathways are widely employed in eukaryotes and are implicated in the regulation of diverse biological processes. In Saccharomyces cerevisiae, at least two different calcium uptake systems have been identified: the high-affinity calcium influx system (HACS) and the low-affinity calcium influx system (LACS). Compared to the HACS, the LACS in fungi is not well known. In this study, FigA, a homolog of the LACS member Fig1 from S. cerevisiae, was functionally characterized in the filamentous fungus Aspergillus nidulans. Loss of figA resulted in retardant hyphal growth and a sharp reduction of conidial production. Most importantly, FigA is essential for the homothallic mating (self-fertilization) process; further, FigA is required for heterothallic mating (outcrossing) in the absence of HACS midA. Interestingly, in a figA deletion mutant, adding extracellular Ca(2+) rescued the hyphal growth defects but could not restore asexual and sexual reproduction. Furthermore, quantitative PCR results revealed that figA deletion sharply decreased the expression of brlA and nsdD, which are known as key regulators during asexual and sexual development, respectively. In addition, green fluorescent protein (GFP) tagging at the C terminus of FigA (FigA::GFP) showed that FigA localized to the center of the septum in mature hyphal cells, to the location between vesicles and metulae, and between the junctions of metulae and phialides in conidiophores. Thus, our findings suggest that FigA, apart from being a member of a calcium uptake system in A. nidulans, may play multiple unexplored roles during hyphal growth and asexual and sexual development.

  3. Developing principles of growth

    DEFF Research Database (Denmark)

    Neergaard, Helle; Fleck, Emma

    of the principles of growth among women-owned firms. Using an in-depth case study methodology, data was collected from women-owned firms in Denmark and Ireland, as these countries are similar in contextual terms, e.g. population and business composition, dominated by micro, small and medium-sized enterprises......Although it has been widely recognized that the growth of women-owned businesses is central to wealth creation, innovation and economic development; limited attention has been devoted to understanding small business growth from a female perspective.This research seeks to develop an understanding....... Extending on principles put forward in effectuation theory, we propose that women grow their firms according to five principles which enable women’s enterprises to survive in the face of crises such as the current financial world crisis....

  4. A prospective investigation of the impact of childhood sexual abuse on the development of sexuality.

    Science.gov (United States)

    Noll, Jennie G; Trickett, Penelope K; Putnam, Frank W

    2003-06-01

    The sexual attitudes and activities of 77 sexually abused and 89 comparison women (mean age = 20.41, SD = 3.38) were assessed 10 years after disclosure in a longitudinal, prospective study of the long-term effects of childhood sexual abuse. Abused participants were more preoccupied with sex, younger at first voluntary intercourse, more likely to have been teen mothers, and endorsed lower birth controlefficacy than comparison participants. When psychological functioning earlier in development was examined, sexual preoccupation was predicted by anxiety, sexual aversion was predicted by childhood sexual behavior problems, and sexual ambivalence (simultaneous sexual preoccupation and sexual aversion) was predicted by pathological dissociation. Findings also indicate that biological father abuse may be associated with greater sexual aversion and sexual ambivalence.

  5. Sexual development in a 21 month-old boy caused by testosterone contamination of a topical hydrocortisone cream.

    Science.gov (United States)

    Svoren, Britta M; Wolfsdorf, Joseph I

    2005-05-01

    Sexual development, including enlargement of the penis, growth acceleration, and growth of pubic hair without an increase in the size of his testes, occurred in a 21 month-old boy over a period of several months. The sexual development was caused by dermal exposure to a hydrocortisone cream, prescribed for eczema, which was contaminated by testosterone. After use of the cream was discontinued, sexual development ceased.

  6. Evidence for the secondary sexual development of the anal fin in female kokanee salmon Oncorhynchus nerka.

    Science.gov (United States)

    Thorn, M W; Morbey, Y E

    2016-02-01

    This study examines whether the anal fin undergoes secondary sexual development similar to other reproductive traits in salmonids. This hypothesis was tested by comparing the anal-fin size of female kokanee salmon Oncorhynchus nerka that were in the early and late stages of sexual development. Females in an advanced stage of maturation had significantly larger anal fins relative to females in an early state of maturation (+4-7%), indicating that the anal fin undergoes secondary sexual development. The magnitude of this secondary growth was comparable with snout length (+9-10%), which is known to undergo secondary sexual development in female salmonids. When morphological trait dimensions were compared between the sexes, the anal fin was the only morphological trait found to have a female-biased sexual size dimorphism. This is the first study to show that the anal fin of female salmonids undergoes secondary sexual development. © 2015 The Fisheries Society of the British Isles.

  7. Improving Sexuality Education: The Development of Teacher-Preparation Standards

    Science.gov (United States)

    Barr, Elissa M.; Goldfarb, Eva S.; Russell, Susan; Seabert, Denise; Wallen, Michele; Wilson, Kelly L.

    2014-01-01

    Background: Teaching sexuality education to support young people's sexual development and overall sexual health is both needed and supported. Data continue to highlight the high rates of teen pregnancy, sexually transmitted disease, including human immunodeficiency virus (HIV) infections, among young people in the United States as well as the…

  8. Effects of exposure to 17{alpha}-ethynylestradiol during larval development on growth, sexual differentiation, and abundances of transcripts in the liver of the wood frog (Lithobates sylvaticus)

    Energy Technology Data Exchange (ETDEWEB)

    Tompsett, Amber R., E-mail: amber.tompsett@usask.ca [Toxicology Centre, University of Saskatchewan, Saskatoon, SK (Canada); Wiseman, Steve; Higley, Eric [Toxicology Centre, University of Saskatchewan, Saskatoon, SK (Canada); Giesy, John P. [Toxicology Centre, University of Saskatchewan, Saskatoon, SK (Canada); Dept. of Veterinary Biomedical Sciences, University of Saskatchewan, Saskatoon, SK (Canada); Dept. of Biology and Chemistry and State Key Laboratory for Marine Pollution, City University of Hong Kong, Hong Kong, Special Administrative Region (Hong Kong); Hecker, Markus [Toxicology Centre, University of Saskatchewan, Saskatoon, SK (Canada); School of the Environment and Sustainability, University of Saskatchewan, Saskatoon, SK (Canada)

    2013-01-15

    Populations of amphibians are in decline in certain locations around the world, and the possible contribution of environmental contaminants, including estrogenic compounds, to these declines is of potential concern. In the current study, responses of the wood frog (Lithobates sylvaticus) to exposure to 17{alpha}-ethynylestradiol (EE2), the synthetic estrogen used in oral contraceptives, during the larval period were characterized. Exposure of L. sylvaticus to 1.08, 9.55, or 80.9 {mu}g EE2/L had no effects on survival, growth, or metamorphic endpoints monitored in the current study. However, there were significant effects of exposure to EE2 on phenotypic sex ratios. In general, lesser proportions of L. sylvaticus developed as phenotypic males and greater proportions developed as phenotypic females or with mixed sex phenotypes at all concentrations of EE2 tested. Utilizing the data collected in the current study, the EC{sub 50} for complete feminization of L. sylvaticus was determined to be 7.7 {mu}g EE2/L, and the EC{sub 50} for partial feminization was determined to be 2.3 {mu}g EE2/L. In addition, after chronic exposure, abundances of transcripts of vitellogenin A2, high density lipoprotein binding protein, and 7-dehydrocholesterol reductase were 1.8-280-fold greater in livers from L. sylvaticus exposed to EE2 compared to controls. Overall, there were significant effects of exposure to all concentrations of EE2 tested, the least of which was within about 2-fold of estrogen equivalent concentrations previously measured in the environment.

  9. Effects of exposure to 17α-ethynylestradiol during larval development on growth, sexual differentiation, and abundances of transcripts in the liver of the wood frog (Lithobates sylvaticus)

    International Nuclear Information System (INIS)

    Tompsett, Amber R.; Wiseman, Steve; Higley, Eric; Giesy, John P.; Hecker, Markus

    2013-01-01

    Populations of amphibians are in decline in certain locations around the world, and the possible contribution of environmental contaminants, including estrogenic compounds, to these declines is of potential concern. In the current study, responses of the wood frog (Lithobates sylvaticus) to exposure to 17α-ethynylestradiol (EE2), the synthetic estrogen used in oral contraceptives, during the larval period were characterized. Exposure of L. sylvaticus to 1.08, 9.55, or 80.9 μg EE2/L had no effects on survival, growth, or metamorphic endpoints monitored in the current study. However, there were significant effects of exposure to EE2 on phenotypic sex ratios. In general, lesser proportions of L. sylvaticus developed as phenotypic males and greater proportions developed as phenotypic females or with mixed sex phenotypes at all concentrations of EE2 tested. Utilizing the data collected in the current study, the EC 50 for complete feminization of L. sylvaticus was determined to be 7.7 μg EE2/L, and the EC 50 for partial feminization was determined to be 2.3 μg EE2/L. In addition, after chronic exposure, abundances of transcripts of vitellogenin A2, high density lipoprotein binding protein, and 7-dehydrocholesterol reductase were 1.8–280-fold greater in livers from L. sylvaticus exposed to EE2 compared to controls. Overall, there were significant effects of exposure to all concentrations of EE2 tested, the least of which was within about 2-fold of estrogen equivalent concentrations previously measured in the environment.

  10. Lung growth and development.

    Science.gov (United States)

    Joshi, Suchita; Kotecha, Sailesh

    2007-12-01

    Human lung growth starts as a primitive lung bud in early embryonic life and undergoes several morphological stages which continue into postnatal life. Each stage of lung growth is a result of complex and tightly regulated events governed by physical, environmental, hormonal and genetic factors. Fetal lung liquid and fetal breathing movements are by far the most important determinants of lung growth. Although timing of the stages of lung growth in animals do not mimic that of human, numerous animal studies, mainly on sheep and rat, have given us a better understanding of the regulators of lung growth. Insight into the genetic basis of lung growth has helped us understand and improve management of complex life threatening congenital abnormalities such as congenital diaphragmatic hernia and pulmonary hypoplasia. Although advances in perinatal medicine have improved survival of preterm infants, premature birth is perhaps still the most important factor for adverse lung growth.

  11. How Peer Education Changed Peer Sexuality Educators' Self-Esteem, Personal Development, and Sexual Behavior.

    Science.gov (United States)

    Sawyer, Robin G.; And Others

    1997-01-01

    This study measured changes in self-esteem, personal development, and sexual behavior over one academic year in 65 sexuality peer educators from 10 universities. Qualitative data described a positive, though non-statistically significant, increase in peer educators' self-esteem, personal development, and sexual behavior as major program outcomes.…

  12. Sexuality among Adolescents with Moderate Disabilities: Promoting Positive Sexual Development

    Science.gov (United States)

    Harader, Dana L.; Fullwood, Harry; Hawthorne, Melissa

    2009-01-01

    Adolescents with moderate disabilities are not being given vital information regarding their sexuality and ways to behave responsibly with their peers. This article examines the laws that govern the education of all persons with disabilities, how societal norms and attitudes have contributed to this lack of sexuality knowledge, how these…

  13. [Sexual development in the light of socio-cultural changes].

    Science.gov (United States)

    Strauss, Bernhard

    2007-01-01

    This article briefly summarizes central components of theories of sexual development and outlines that these components depend largely on socio-cultural factors. A cultural change of human sexuality is reflected by several phenomena such as the public debate about sexual violence and its consequences, a diminuation of gender differences and a turn away from monosexuality, tremendous changes within the world of partner relationships and a mediatization of sexuality. This mediatization is paralleled by a public sexualization as well as a de-sexualization of the private sphere together with an increase of a loss of sexual desire reflecting well-known problems of human sexuality. Finally, it has to be stated that sexuality has experienced a demystification as a consequence of socio-cultural changes following the sexual liberalization.

  14. Growth in Adolescent Self-Regulation and Impact on Sexual Risk-Taking: A Curve-of-Factors Analysis.

    Science.gov (United States)

    Crandall, AliceAnn; Magnusson, Brianna M; Novilla, M Lelinneth B

    2018-04-01

    Adolescent self-regulation is increasingly seen as an important predictor of sexual risk-taking behaviors, but little is understood about how changes in self-regulation affect later sexual risk-taking. Family financial stress may affect the development of self-regulation and later engagement in sexual risk-taking. We examined whether family financial stress influences self-regulation in early adolescence (age 13) and growth in self-regulation throughout adolescence (from age 13-17 years). We then assessed the effects of family financial stress, baseline self-regulation, and the development of self-regulation on adolescent sexual risk-taking behaviors at age 18 years. Using a curve-of-factors model, we examined these relationships in a 6-year longitudinal study of 470 adolescents (52% female) and their parents from a large northwestern city in the United States. Results indicated that family financial stress was negatively associated with baseline self-regulation but not with growth in self-regulation throughout adolescence. Both baseline self-regulation and growth in self-regulation were predictive of decreased likelihood of engaging in sexual risk-taking. Family financial stress was not predictive of later sexual risk-taking. Intervening to support the development of self-regulation in adolescence may be especially protective against later sexual risk-taking.

  15. Zinc and somato-sexual development of adolescents

    Directory of Open Access Journals (Sweden)

    S.I. Turchina

    2017-03-01

    to expand existing concepts about the influence of Zn deficiency disorders on the physical and sexual development in adolescents. Materials and methods. In 70 adolescent boys aged 10–17 years Zn level was evaluated, taking into account somato-sexual development and the presence of diffuse nontoxic goiter (DNG. Teens were divided into groups: 1 20 boys aged 10–17 years with normal volume of the thyroid gland, normal physical and sexual development; 2 17 adolescents aged 14–17 years with normal sexual development and DNG; 3 15 adolescents aged 14–17 years with sexual deve­lopment delay (SDD and normal thyroid volume; 4 18 adolescents aged 14–17 years with SDD and DNG. Results. The highest values of Zn were determined during the physiological puberty by itself within its physiologic course ((16.52; 14.27–18.66 mmol/l, which is significantly more than in the pre- ((13.53; 12.77–16.41 mmol/l; p < 0.05 and late puberty ((12.59; 10.22–16.07 mmol/l; p < 0.05. The adolescents with SDD ((14.41; 12.67–15.83 mmol/l and short stature ((12.53; 8.80–15.46 mmol/l had decreased Zn level, especially in the case of DNG ((10.03; 8.51–13.76 mmol/l. Regression and factor analysis studied the nature of the relationship between anthropometric indices, the degree of development of se­condary sexual characteristics and Zn, functional state of the thyroid and reproductive systems. Conclusions. During puberty period Zn rates varies achieving its maximum level during the puberty by itself. Delayed growth and sexual development are associated with reduced Zn concentration in blood. The lowest Zn value is typical for the adolescents with DNG and SDD. There was grounded the necessity of Zincite drug application as a monotherapy or included into the complex treatment for the secondary prevention and treatment of Zn deficiency.

  16. Faith and Sexual Orientation Identity Development in Gay College Men

    Science.gov (United States)

    Dunn, Merrily; Glassmann, Danny; Garrett, J. Matthew; Badaszewski, Philip; Jones, Ginny; Pierre, Darren; Fresk, Kara; Young, Dallin; Correll-Hughes, Larry

    2015-01-01

    This study examines the experiences of gay-identified college men related to their faith and sexual orientation identity development. The findings suggest that for gay-identified college men, faith and sexual orientation identity development includes examination of one's faith and sexual orientation identity, important relationships, and a desire…

  17. On early starters and late bloomers: the development of sexual behavior in adolescence across personality types.

    Science.gov (United States)

    Baams, Laura; Overbeek, Geertjan; Dubas, Judith Semon; van Aken, Marcel A G

    2014-01-01

    Little is known about the relationship between personality and sexual development among mid-adolescents. In the current study, we used a person-centered approach to investigate the relation between personality types and the development of sexual behavior. We hypothesized that undercontrolling adolescents would engage in more advanced, casual, and risky sexual behavior compared to their resilient and overcontrolling peers. Data were used from 407 mid-adolescents (Mage = 14.5) followed across four measurement waves spanning 18 months. Results from latent class analyses (LCA) identified the three classical personality types: resilients, undercontrollers, and overcontrollers. Controlling for perceived pubertal timing and biological sex, latent growth curve analyses in Mplus showed that, at baseline, undercontrollers were more sexually experienced and engaged in more casual and risky sexual behavior than resilients and overcontrollers. Although initial levels of sexual behavior differed by personality types, over time increases in sexual behavior occurred at a similar rate across the types. Overall, the current study showed that undercontrolling adolescents are early sexual developers who engage in more advanced, casual, and risky sexual behavior than other adolescents. The implications of these findings for longer-term differences in sexual behavior between personality types in later adolescence are discussed.

  18. Sexual hormones modulate compensatory renal growth and function

    Directory of Open Access Journals (Sweden)

    Pablo J. Azurmendi

    2013-12-01

    Full Text Available The role played by sexual hormones and vasoactive substances in the compensatory renal growth (CRG that follows uninephrectomy (uNx is still controversial. Intact and gonadectomized adult Wistar rats of both sexes, with and without uNx, performed at 90 days age, were studied at age 150 days. Daily urine volume, electrolyte excretion and kallikrein activity (UKa were determined. Afterwards, glomerular filtration rate and blood pressure were measured, the kidneys weighed and DNA, protein and RNA studied to determine nuclei content and cell size. When the remnant kidney weight at age 150 days was compared with the weight of the kidney removed at the time of uNx, male uNx rats showed the greatest CRG (50% while growth in the other uNx groups was 25%, 15% and 19% in orchidectomized, female and ovariectomized rats, respectively. The small CRG observed in the uNx female rats was accompanied by the lowest glomerular filtration value, 0.56 ± 0.02 ml/min/g kwt compared, with the other uNx groups, p < 0.05. Cell size (protein or RNA/DNA was similar for all the groups except for uNx orchidectomized rats. In this group the cytoplasmatic protein or RNA content was lower than in the other groups while DNA (nuclei content was similar. Some degree of hyperplasia was determined by DNA content in the uNx groups. Male sexual hormones positively influenced CRG and its absence modulated cell size. Female sexual hormones, instead, did not appear to stimulate CRG. The kallikrein kinin system may not be involved in CRG.

  19. Sexual hormones modulate compensatory renal growth and function.

    Science.gov (United States)

    Azurmendi, Pablo J; Oddo, Elisabet M; Toledo, Jorge E; Martin, Rodolfo S; Ibarra, Fernando R; Arrizurieta, Elvira E

    2013-01-01

    The role played by sexual hormones and vasoactive substances in the compensatory renal growth (CRG) that follows uninephrectomy (uNx) is still controversial. Intact and gonadectomized adult Wistar rats of both sexes, with and without uNx, performed at 90 days age, were studied at age 150 days. Daily urine volume, electrolyte excretion and kallikrein activity (UKa) were determined. Afterwards, glomerular filtration rate and blood pressure were measured, the kidneys weighed and DNA, protein and RNA studied to determine nuclei content and cell size. When the remnant kidney weight at age 150 days was compared with the weight of the kidney removed at the time of uNx, male uNx rats showed the greatest CRG (50%) while growth in the other uNx groups was 25%, 15% and 19% in orchidectomized, female and ovariectomized rats, respectively. The small CRG observed in the uNx female rats was accompanied by the lowest glomerular filtration value, 0.56 ± 0.02 ml/ min/g kwt compared, with the other uNx groups, p hormones positively influenced CRG and its absence modulated cell size. Female sexual hormones, instead, did not appear to stimulate CRG. The kallikrein kinin system may not be involved in CRG.

  20. Inhabiting the sexual landscape: toward an interpretive theory of the development of sexual orientation and identity.

    Science.gov (United States)

    Gordon, Liahna E; Silva, Tony J

    2015-01-01

    Building on Paula Rust's (1996) concept of a sexual landscape, we propose an interpretive theory of the development of both sexual orientation and sexual identity. We seek to reconcile human agency with active and shifting influences in social context and to recognize the inherent complexity of environmental factors while acknowledging the role that biological potential plays. We ground our model in the insights of three compatible and related theoretical perspectives: social constructionism, symbolic interactionism, and scripting theory. Within this framework, we explain how sexual orientation and sexual identities develop and potentially change.

  1. Aid, Growth, and Development

    DEFF Research Database (Denmark)

    Arndt, Channing; Jones, Edward Samuel; Tarp, Finn

    This paper uses a unique panel dataset on firm-level corruption. It contains quantitative information on bribe payments by a sample of formal and informal Vietnamese firms. We show that bribe incidence is highly associated with firm-level differences in (i) visibility, (ii) sunk costs, (iii......, this premium outweighs the additional bribe cost of formalization. Formalization embodies net benefits in spite of the growth hampering effects of bribes....

  2. Individual-Based Compulsive Sexual Behavior Scale: Its Development and Importance in Examining Compulsive Sexual Behavior.

    Science.gov (United States)

    Efrati, Yaniv; Mikulincer, Mario

    2018-04-03

    Compulsive sexual behavior comprises individual-based (e.g., sexual fantasies, compulsive sexual thoughts, masturbation) and partnered (e.g., interpersonal sexual conquests, repeated infidelity) facets. Most instruments for assessing compulsive sexual behavior, however, focus less on the individual-based facet and specifically on fantasies and compulsive thoughts. In the current research, we developed and validated an individual-based compulsive sexual behavior scale (I-CSB). In Study 1 (N = 492), the factorial structure of the I-CSB was examined. In Study 2 (N = 406), we assessed I-CSB's convergent validity. In Study 3 (N = 112), we examined whether the I-CSB differentiates between individuals who suffer from compulsive sexual behavior and those who do not. Results revealed a four-factor structure for individual-based compulsive sexual behavior that is associated with an intense inner conflict regarding sexuality (high arousal contrasting with high sexual anxiety), and that accounts for approximately 75% of the differences between people with compulsive sexual behavior and controls. Results are discussed in light of the need for a broader understanding of compulsive sexual behavior.

  3. Sexual Practices and their Development Pattern among Jimma ...

    African Journals Online (AJOL)

    BACKGROUND: Traditional views of sexual behaviors are frequently changing as the factors influencing them are changing. Therefore, assessing sexual practices that are not part of the tradition would be necessary. The objective of this study was to identify the types of sexual practices, their development pattern and how ...

  4. Autism and normative sexual development : A narrative review

    NARCIS (Netherlands)

    Dewinter, J.; Vermeiren, R.; Vanweesenbeeck, I.; van Nieuwenhuizen, Ch.

    2013-01-01

    Aims and objectives To explore the existing knowledge on sexuality and autism spectrum disorders. To this end, the concept of normative sexual development was used as an organising framework. Background Sexual health can be seen as a developmental task for all children, adolescents and adults. Core

  5. Autism and normative sexual development: a narrative review

    NARCIS (Netherlands)

    Dewinter, J.; Vermeiren, R.R.J.M.; Vanwesenbeeck, I.; van Nieuwenhuizen, C.

    2013-01-01

    Aims and objectives: To explore the existing knowledge on sexuality and autism spectrum disorders. To this end, the concept of normative sexual development was used as an organising framework. Background: Sexual health can be seen as a developmental task for all children, adolescents and adults.

  6. Effects of active immunization against GnRH on serum LH, inhibin A, sexual development and growth rate in Chinese female pigs.

    Science.gov (United States)

    Zeng, X Y; Turkstra, J A; Tsigos, A; Meloen, R H; Liu, X Y; Chen, F Q; Schaaper, W M M; Oonk, H B; Guo, D Z; van de Wiel, D F M

    2002-10-15

    and intact controls. Although not significant, immunocastrates had a numerically higher average daily gain than surgical castrates and intact controls (0.74 +/- 0.04 versus 0.66 +/- 0.04 versus 0.66 +/- 0.03 kg per day, respectively; mean +/- S.E.M., P = 0.09). Results obtained in the present study demonstrate that anti-GnRH immunization can be an attractive alternative to surgical castration for Chinese crossbred female pigs. Our results also question the beneficial effect of surgical castration on growth as compared to intact controls.

  7. Molecular mechanisms of secondary sexual trait development in insects.

    Science.gov (United States)

    Prakash, Anupama; Monteiro, Antónia

    2016-10-01

    Secondary sexual traits are those traits other than the primary gametes that distinguish the sexes of a species. The development of secondary sexual traits occurs when sexually dimorphic factors, that is, molecules differentially produced by primary sex determination systems in males and females, are integrated into the gene regulatory networks responsible for sexual trait development. In insects, these molecular asymmetric factors were always considered to originate inside the trait-building cells, but recent work points to external factors, such as hormones, as potential candidates mediating secondary sexual trait development. Here, we review examples of the different molecular mechanisms producing sexually dimorphic traits in insects, and suggest a need to revise our understanding of secondary sexual trait development within the insect lineage. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. The development of a measure of correlates of child sexual abuse: the Traumatic Sexualization Survey.

    Science.gov (United States)

    Matorin, A I; Lynn, S J

    1998-04-01

    The present research developed an instrument which assesses cognitive and behavioral factors purportedly associated with child sexual abuse histories. Finkelhor and Browne's construct of traumatic sexualization served as a guide for item selection. The study resulted in a 38-item reliable measure consisting of four subscales: Avoidance and Fear of Sexual and Physical Intimacy, Thoughts About Sex, Role of Sex in Relationships, and Attraction/Interest and Sexuality. Construct validity was established using a variety of self-report instruments associated with the dimensions of traumatic sexualization. Sexually abused women scored higher than nonabused women on three TSS factors. Physically abused women differed from nonabused women on only one factor. Sexually abused women did not score significantly higher than physically abused women on any factors.

  9. Buffer or Brake? The Role of Sexuality-Specific Parenting in Adolescents’ Sexualized Media Consumption and Sexual Development

    NARCIS (Netherlands)

    G.J. Overbeek (Geertjan); van de Bongardt, D. (Daphne); Baams, L. (Laura)

    2018-01-01

    textabstractOne main source of sexual socialization lies within family interactions. Especially sexuality-specific parenting may determine adolescents’ sexual development—adolescents’ sexual behavior and sexual risk behavior, sexualized media consumption and permissive sexual attitudes—to a

  10. Buffer or Brake? The Role of Sexuality-Specific Parenting in Adolescents’ Sexualized Media Consumption and Sexual Development

    NARCIS (Netherlands)

    Overbeek, Geertjan; van de Bongardt, Daphne; Baams, Laura

    2018-01-01

    One main source of sexual socialization lies within family interactions. Especially sexuality-specific parenting may determine adolescents’ sexual development—adolescents’ sexual behavior and sexual risk behavior, sexualized media consumption and permissive sexual attitudes—to a significant extent,

  11. Improving sexuality education: the development of teacher-preparation standards.

    Science.gov (United States)

    Barr, Elissa M; Goldfarb, Eva S; Russell, Susan; Seabert, Denise; Wallen, Michele; Wilson, Kelly L

    2014-06-01

    Teaching sexuality education to support young people's sexual development and overall sexual health is both needed and supported. Data continue to highlight the high rates of teen pregnancy, sexually transmitted disease, including human immunodeficiency virus (HIV) infections, among young people in the United States as well as the overwhelming public support for sexuality education instruction. In support of the implementation of the National Sexuality Education Standards, the current effort focuses on better preparing teachers to deliver sexuality education. An expert panel was convened by the Future of Sex Education Initiative to develop teacher-preparation standards for sexuality education. Their task was to develop standards and indicators that addressed the unique elements intrinsic to sexuality education instruction. Seven standards and associated indicators were developed that address professional disposition, diversity and equity, content knowledge, legal and professional ethics, planning, implementation, and assessment. The National Teacher-Preparation Standards for Sexuality Education represent an unprecedented unified effort to enable prospective health education teachers to become competent in teaching methodology, theory, practice of pedagogy, content, and skills, specific to sexuality education. Higher education will play a key role in ensuring the success of these standards. © 2014, American School Health Association.

  12. New developments in education and training in sexual medicine.

    Science.gov (United States)

    Reisman, Yacov; Eardley, Ian; Porst, Hartmut

    2013-04-01

    INTRODUCTION.: The past 12 months have been historic ones for the field of Sexual Medicine in that we have seen the creation of the European Board examination in Sexual Medicine with the title of "Fellow of the European Committee on Sexual Medicine" (FECSM) offered to successful candidates. AIM.: The study aims to promote a high standard of care in Sexual Medicine. METHODS.: An important way of promoting high standards of care is by the development of training, regulation, and assessment framework. The background to these developments and the recent educational activities of the European Society for Sexual Medicine (ESSM) are described in this article. RESULTS.: The creation of the Multidisciplinary Joint Committee on Sexual Medicine (MJCSM) under the auspices of the European Union of Medical Specialists, with the primary purpose to develop the highest possible standards of training in Sexual Medicine in Europe, made it possible to create a process for qualification in Sexual Medicine. The ESSM educational activities created opportunities to support trainees in Sexual Medicine and the first MJCSM exam was held in Amsterdam with a high overall success rate. CONCLUSION.: These activities are intended to improve quality. The FECSM examination is the first of its type and provides a real opportunity for Sexual Medicine physicians to demonstrate and document their knowledge. © 2013 International Society for Sexual Medicine.

  13. A Prospective Investigation of the Impact of Childhood Sexual Abuse on the Development of Sexuality

    OpenAIRE

    Noll, Jennie G.; Trickett, Penelope K.; Putnam, Frank W.

    2003-01-01

    The sexual attitudes and activities of 77 sexually abused and 89 comparison women (mean age = 20.41, SD = 3.38) were assessed 10 years after disclosure in a longitudinal, prospective study of the long-term effects of childhood sexual abuse. Abused participants were more preoccupied with sex, younger at first voluntary intercourse, more likely to have been teen mothers, and endorsed lower birth control efficacy than comparison participants. When psychological functioning earlier in development...

  14. Autism and normative sexual development: a narrative review.

    Science.gov (United States)

    Dewinter, Jeroen; Vermeiren, Robert; Vanwesenbeeck, Ine; van Nieuwenhuizen, Chijs

    2013-12-01

    To explore the existing knowledge on sexuality and autism spectrum disorders. To this end, the concept of normative sexual development was used as an organising framework. Sexual health can be seen as a developmental task for all children, adolescents and adults. Core autism features are related with skills central to sexual development and functioning. More insight in sexual development in people with autism is relevant for education, support and interventions by parents and professionals in somatic and mental health care. A comprehensive search of scientific online databases and reference lists was conducted. Publications based on qualitative and quantitative research, including case studies, were selected. Fifty-five articles and reports were selected and discussed. Information was grouped according to three domains: sexual behaviour, sexual selfhood and sexual socialisation. Sexual development is a part of life for people with autism of all developmental levels and is generally understudied in this population. Most information was available on behavioural aspects and experiences of socialising agents, such as parents and professionals. Developmental processes and the relation between sexual behaviour, selfhood and socialisation remained unclear. Nurses working in schools, institutions and general health care support children, adolescents and adults with autism and advice their families, teachers, other educators and caregivers on sexuality issues. They can have an important role in daily assessment and support of this developmental domain by actively enquiring about the different aspects of sexual development and by offering information. Our findings offer an overview on the existing knowledge and support the idea that sexual development is normative for people with autism just as for anybody else. © 2013 John Wiley & Sons Ltd.

  15. Postnatal growth and development of the hairy-footed gerbil,

    African Journals Online (AJOL)

    1989-12-14

    Dec 14, 1989 ... observed at the same time intervals as growth. The physical development of the pelage, limbs, eyes, ears, teeth and reproductive organs was noted. Behavioural observations were made with regard to feeding, locomotion, audible vocalization, grooming, exploration and sexual behaviour. Depth perception ...

  16. Sexual Assertiveness Scale (SAS) for women: development and validation.

    Science.gov (United States)

    Morokoff, P J; Quina, K; Harlow, L L; Whitmire, L; Grimley, D M; Gibson, P R; Burkholder, G J

    1997-10-01

    Four studies were conducted to develop and validate the Sexual Assertiveness Scale (SAS), a measure of sexual assertiveness in women that consists of factors measuring initiation, refusal, and pregnancy-sexually transmitted disease prevention assertiveness. A total of 1,613 women from both university and community populations were studied. Confirmatory factor analyses demonstrated that the 3 factors remained stable across samples of university and community women. A structural model was tested in 2 samples, indicating that sexual experience, anticipated negative partner response, and self-efficacy are consistent predictors of sexual assertiveness. Sexual assertiveness was found to be somewhat related to relationship satisfaction, power, and length. The community sample was retested after 6 months and 1 year to establish test-retest reliability. The SAS provides a reliable instrument for assessing and understanding women's sexual assertiveness.

  17. Employment growth and regional development

    DEFF Research Database (Denmark)

    Eriksson, Rikard; Hansen, Høgni Kalsø; Winther, Lars

    2017-01-01

    This paper explores the potential drivers behind uneven regional development in the context of employment growth in Denmark and Sweden. In particular, we are interested in the roles of urbanization, industrial change and the rise of the new economy as manifested in the growth of the two economies...... in 2002–2007. The aim of this paper is, therefore, to analyse the impact of a number of key industrial sectors on regional employment growth in the two countries. The empirical analysis is based on longitudinal matched employer–employee data retrieved from official registers in each economy from 2002...... to 2007, a period of strong national growth following the crisis of early 2000. Our findings indicate that the two economies follow a similar pattern in addressing total employment growth; but looking at changes in employment levels across the national borders of these two relatively similar open...

  18. Development of a sexual function questionnaire for clinical trials of female sexual dysfunction

    NARCIS (Netherlands)

    Quirk, Frances H.; Heiman, Julia R.; Rosen, Raymond C.; Laan, Ellen; Smith, Michael D.; Boolell, Mitra

    2002-01-01

    OBJECTIVE: To better evaluate efficacy in clinical trials of drugs as potential treatments for female sexual dysfunctions (FSD), a brief, multidimensional measure of female sexual function was developed. METHODS: Data from semistructured interviews with 82 women with or without FSD, aged 19-65

  19. Alcohol and Sexual Consent Scale: Development and Validation

    Science.gov (United States)

    Ward, Rose Marie; Matthews, Molly R.; Weiner, Judith; Hogan, Kathryn M.; Popson, Halle C.

    2012-01-01

    Objective: To establish a short measure of attitudes toward sexual consent in the context of alcohol consumption. Methods: Using a multistage and systematic measurement development process, the investigators developed the Alcohol and Sexual Consent Scale using a sample of college students. Results: The resulting 12-item scale, the Alcohol and…

  20. An Ethnographic Analysis of Adolescent Sexual Minority Website Usage: Exploring Notions of Information Seeking and Sexual Identity Development

    Science.gov (United States)

    Sulfridge, Rocky M.

    2012-01-01

    This dissertation explores the website usage of adolescent sexual minorities, examining notions of information seeking and sexual identity development. Sexual information seeking is an important element within human information behavior and is uniquely problematic for young sexual minorities. Utilizing a contemporary gay teen website, this…

  1. The Development of the Sexual Assertiveness Questionnaire (SAQ): A Comprehensive Measure of Sexual Assertiveness for Women.

    Science.gov (United States)

    Loshek, Eevett; Terrell, Heather K

    2015-01-01

    Sexual assertiveness has been defined in a number of ways by many researchers, with different aspects of sexual assertiveness emphasized in different measures. Most previous measures have included condom insistence as an important aspect of sexual assertiveness, but this may not translate well to women at all life stages or in varied types of relationships. The goal of the current study was to develop a comprehensive measure of sexual assertiveness that encompasses the aspects of sexual assertiveness that have been emphasized by previous researchers, with the exception of condom insistence. Items were generated based on previous measures and definitions, and an exploratory factor analysis was conducted (Study 1) to better understand the dimensions of sexual assertiveness. The proposed scale was revised and further refined using both exploratory factor analysis and confirmatory factor analysis in Study 2. The final scale consisted of 18 items that seem to capture three dimensions of sexual assertiveness: the ability to initiate and communicate about desired sex, the ability to refuse unwanted sex, and the ability to communicate about sexual history and risk. Model fit indices indicate that this three-factor solution fits the data well. Implications and suggestions for future research are discussed.

  2. Aerobic endurance in young female athletes in respect to sexual maturation, age and growth

    Directory of Open Access Journals (Sweden)

    Maria Tereza Silveira Böhme

    2004-12-01

    Full Text Available The aims of this study were, in young female athletes: a to describe the development of aerobic endurance in relation to different sexual maturation stages by each chronological age; b to verify the existence of significant differences among the sexual maturation stages in each age; c to describe the development of aerobic endurance in relation to different ages by each sexual stage; d to verify the existence of significant differences among the ages by each sexual stage; e to verify the influence of chronological age, sexual maturation, adiposity, muscularity, physical growth and kind of sport on aerobic endurance. The sample comprised 305 female young athletes from 10 to 17 years of age, of basketball, handball, soccer and track and field, who were measured for their physical growth, adiposity, muscularity, sexual maturation stage and aerobic endurance. The variance and multiple regression analyses indicated that sexual maturation had no significant influence on the aerobic endurance of these female young athletes. RESUMO Este trabalho de pesquisa teve por objetivos, com relação a jovens atletas do sexo feminino: a descrever o desenvolvimento da resistência geral aeróbia considerando-se os diferentes níveis de maturação biológica em cada idade cronológica; b verificar a existência de diferenças significativas entre os níveis de maturação em cada idade cronológica; c descrever o desenvolvimento da resistência geral aeróbia considerando-se as diferentes idades cronológicas em cada nível de maturação biológica; d verificar a existência de diferenças significativas entre as idades cronológicas de mesmo estágio maturacional; e verificar a influência da maturação biológica, crescimento físico, adiposidade subcutânea, muscularidade, idade cronológica e o tipo de modalidade esportiva praticada sobre a resistência geral aeróbia. Para isso, uma amostra de 305 jovens atletas mulheres na faixa etária de 10 a 17 anos das

  3. Growth charts of human development

    NARCIS (Netherlands)

    Buuren, S. van

    2014-01-01

    This article reviews and compares two types of growth charts for tracking human development over age. Both charts assume the existence of a continuous latent variable, but relate to the observed data in different ways. The D-score diagram summarizes developmental indicators into a single aggregate

  4. The Development of Female Sexual Behavior Requires Prepubertal Estradiol

    NARCIS (Netherlands)

    Brock, O.; Baum, M.J.; Bakker, J.

    2011-01-01

    The classic view of brain and behavioral sexual differentiation holds that the neural mechanisms controlling sexual behavior in female rodents develop in the absence ofovarian sex hormone actions. However,inaprevious study, female aromatase knock-out (ArKO) mice, which cannot convert testosterone to

  5. Development and validation of the response to sexual difficulties scale.

    Science.gov (United States)

    Fallis, Erin E; Purdon, Christine; Rehman, Uzma S

    2013-01-01

    Leading models of sexual dysfunction, such as those proposed by Masters and Johnson (1970), Barlow (1986), and Janssen, Everaerd, Spiering, and Janssen (2000), emphasize the role of anxiety and self-monitoring in the development and persistence of sexual difficulties. These models have considerable explanatory power, but focus on the intrapersonal factors that yield anxiety and self-monitoring. Accounting for the interpersonal context in which sexual activity occurs is also likely to be important. For example, anxiety and self-monitoring may arise from negative, yet accurate, predictions about how one's partner will respond to one's own sexual functioning difficulties. The current studies describe the development and validation of the Response to Sexual Difficulties Scale (RSDS), which was designed to assess how one expects one's partner to respond to one's own sexual difficulties (RSDS-Own Difficulties) and how one expects oneself to respond to one's partner's sexual difficulties (RSDS-Partner Difficulties). Study 1 established the initial reliability and construct validity of the RSDS-Own Difficulties in a sample of adults in committed relationships (N = 59). Study 2 further examined the construct and discriminant validity of the RSDS Own Difficulties and Partner Difficulties in a sample of heterosexual couples (N = 87). Results indicated that both measures had strong internal consistency and were not redundant with measures of mood or personality. Scores on the RSDS-Own Difficulties and Partner Difficulties were strongly associated, indicating that reports of one's own response to one's partner's difficulty matched the partner's assessment of the reaction. RSDS scores predicted sexual functioning, relationship satisfaction, sexual satisfaction, and sexual communication. The RSDS may, then, provide a useful means of assessing the role of interpersonal factors in the development and persistence of sexual difficulties.

  6. Sexual development and behaviour issues in Polish teenage magazines.

    Science.gov (United States)

    Kopacz, Marek S

    2006-12-01

    Adolescents often look to mass media for information regarding issues of sexuality. As one form of media, teenage magazines have long constituted a pervasive and effective element of adolescent media exposure. Teenage magazines discuss a number of aspects concerning adolescent sexuality. Considering their potential impact on health related behaviors, the information they provide and the message(s) they send warrant attention. The aim of this study is to perform a content analysis of sexual development and behavior information presented in Polish teenage magazines. Social Cognitive Theory was used as a theoretical basis for this analysis. The media chosen for this study were general-themed publications targeting an adolescent female audience: Bravo Girl!, Filipinka and Dziewczyna. Each entry was analyzed using a structured key. The specific categories of behavior and development used for this study are: biological information, pedagogic instruction, topics of moral-ethical concern, results of sexual activity, and interpersonal relationships. Each category was then subdivided into separate units. The findings indicate that Polish teenage magazines predominantly focus on relationships, contraception and sex education. Relationships were most often of a romantic nature and discussed sexual activity or the potential of sexual activity. Non-prescription contraceptive methods were most often discussed, with attention given to pregnancy prevention. Sex education offered detailed information on sexual practices and behaviors with much discussion on losing one's virginity. The general approach of the analyzed magazines is that adolescents currently are, or soon will be, sexually active. As a result, certain sexual behavior and development issues are discussed in great detail, while other topics are somewhat neglected. Accepting information-seeking during adolescence as commonplace, these findings suggest that teenage magazines hold the potential for influencing adolescent

  7. Population growth and economic development.

    Science.gov (United States)

    Corbridge, S

    1989-01-01

    The Malthusian and neo-Malthusian approaches to the role of population growth in economic development and resource depletion are briefly outlined. Three arguments are then presented that emphasize demographic determinism, empirical evidence, and cause and effect. The author concludes that non-coercive family planning programs may have a role to play in countries that are unable to reduce inequalities, particularly for the poor and for women.

  8. [Children of homoparental families: psychological and sexual development].

    Science.gov (United States)

    Roccella, M

    2005-04-01

    In the last few years some studies have been made about homosexual parenthood and especially if this interferes with the child's development, identity and future sexual tendency. These studies prove that the parents' homosexuality does not seem to compromise the child's psychosexual development and that the child's possible homosexuality does not depend on the parents' sexual behaviour but on different factors linked to the relationship; as a matter of fact there are no relevant differences in the occurrence of homosexuality in children born from homosexual and heterosexual parents. The present study investigated the psychological and sexual development in a group of children of homoparental family. The sample observed included 37 children, 22 male and 15 female. The following psychodiagnostic tests were used for assessment: spontaneous drawing, draw-a-person test, family drawing, blacky pictures test. The developmental of the child's sexual identity was determined through the preferences and fantasies he/she showed while playing, in the relationship with his/her mates, in the way of dressing. We used interviews with the child and the parents. All the children showed a good adherence to their sexual role. The observations and interviews proved that the children's disorders are not linked to the parents' homosexuality. Being brought up by homosexual parents does not seem to compromise the child's future sexual tendency. However, in these children the sexual preference could change in adult life, being influenced by future situations and circumstances.

  9. Effects of sexual maturation and 17ß-Estradiol on nutrient partitioning and mechanisms regulating growth and nutrient metabolism in Rainbow Trout Oncorhynchus mykiss

    Science.gov (United States)

    In female rainbow trout sexual maturation occurs parallel with declines in growth performance and mobilization of nutrient stores that partition energy away from growth and toward gonad development. For this reason sterile triploids are often reared for their ability to produce larger fillets and a...

  10. Sexual Behavior, Sexual Attraction, and Sexual Orientation Among Adults Aged 18-44 in the United States: Data From the 2011-2013 National Survey of Family Growth.

    Science.gov (United States)

    Copen, Casey E; Chandra, Anjani; Febo-Vazquez, Isaedmarie

    2016-01-07

    This report provides national estimates of sexual behavior, sexual attraction, and sexual orientation among women and men aged 18-44 in the United States, based on the 2011-2013 National Survey of Family Growth (NSFG). Data for the 2011-2013 NSFG were collected through in-person interviews with 10,416 women and men aged 15-44 in the household population in the United States. In this report, data are shown only for 9,175 adults aged 18-44. The data presented in this report were primarily collected using audio computer-assisted self-interviewing, in which the respondent enters his or her answers into the computer without telling them to an interviewer. The overall response rate for the 2011-2013 NSFG was 72.8%. Regarding opposite-sex sexual behavior, 94.2% of women and 92.0% of men aged 18-44 had ever had vaginal intercourse; 86.2% of women and 87.4% of men had ever had oral sex; and 35.9% of women and 42.3% of men had ever had anal sex. Almost three times as many women (17.4%) reported any same-sex contact in their lifetime compared with men (6.2%) aged 18-44. Feelings of attraction "only to the opposite sex" were more common for men (92.1%) compared with women (81.0%) aged 18-44. Among those aged 18-44, 92.3% of women and 95.1% of men said they were "heterosexual or straight"; 1.3% of women and 1.9% of men said they were "homosexual, gay, or lesbian"; 5.5% of women and 2.0% of men said they were bisexual; and 0.9% of women and 1.0% of men said "don't know" or "refused" (i.e., "did not report") on sexual orientation. Sexual attraction and sexual orientation correlate closely but not completely with reports of sexual behavior. Sexual behavior, sexual attraction, and sexual orientation vary by age, marital or cohabiting status, education, and race and Hispanic origin. All material appearing in this report is in the public domain and may be reproduced or copied without permission; citation as to source, however, is appreciated.

  11. [Development of sexuality and motivational aspects of sexual behavior in men with obsessive-compulsive disorders].

    Science.gov (United States)

    2014-09-01

    Sexual behavior and formation of sexuality in men with obsessive-compulsive disorder is one of the pressing issues in contemporary medicine. Obsessive-compulsive disorder is characterized by the development of intrusive thoughts, memories, movements and actions, as well as a variety of pathological fears (phobias). Increase in the number of patients with this pathology in modern clinical practice of neurotic disorders, the young age of the patients and as a result violation of interpersonal, communicational and sexual nature is quite apparent. The study involved 35 men aged 23 to 47 years with clinical signs of OCD. We determined the severity of obsessive-compulsive symptoms using the Yale-Brown scale. We established the presence of a mild degree of disorder in 34,3% of cases; in 48,6% of cases disorder of moderate severity was diagnosed; remaining 17.1% were assessed subclinical condition of OCD at the applicable scale. The system of motivational maintenance of sexual behavior in men with obsessive-compulsive disorders is investigated. Motives of sexual behavior of the investigated men with the pathology are determined. The presented research in men with OCD have established multidimensionality and complexity of motivational ensuring of sexual behavior.

  12. The Role of Sexually Explicit Material (SEM) in the Sexual Development of Black Young Same-Sex-Attracted Men

    Science.gov (United States)

    Morgan, Anthony; Ogunbajo, Adedotun; Trent, Maria; Harper, Gary W.; Fortenberry, J. Dennis

    2015-01-01

    Sexually explicit material (SEM) (including Internet, video, and print) may play a key role in the lives of Black same-sex sexually active youth by providing the only information to learn about sexual development. There is limited school-and/or family-based sex education to serve as models for sexual behaviors for Black youth. We describe the role SEM plays in the sexual development of a sample of Black same-sex attracted (SSA) young adolescent men ages 15–19. Adolescents recruited from clinics, social networking sites, and through snowball sampling were invited to participate in a 90-min, semi-structured qualitative interview. Most participants described using SEM prior to their first same-sex sexual experience. Participants described using SEM primarily for sexual development, including learning about sexual organs and function, the mechanics of same-gender sex, and to negotiate one’s sexual identity. Secondary functions were to determine readiness for sex; to learn about sexual performance, including understanding sexual roles and responsibilities (e.g., “top” or “bottom”); to introduce sexual performance scripts; and to develop models for how sex should feel (e.g., pleasure and pain). Youth also described engaging in sexual behaviors (including condom non-use and/or swallowing ejaculate) that were modeled on SEM. Comprehensive sexuality education programs should be designed to address the unmet needs of young, Black SSA young men, with explicit focus on sexual roles and behaviors that may be inaccurately portrayed and/or involve sexual risk-taking (such as unprotected anal intercourse and swallowing ejaculate) in SEM. This work also calls for development of Internet-based HIV/STI prevention strategies targeting young Black SSA men who maybe accessing SEM. PMID:25677334

  13. Effects of obesity on human sexual development.

    Science.gov (United States)

    Wagner, Isabel V; Sabin, Mathew A; Pfäffle, Roland W; Hiemisch, Andreas; Sergeyev, Elena; Körner, Antje; Kiess, Wieland

    2012-01-31

    Puberty is a period of physical and psychological maturation, with long-term effects on health. During the 20(th) century, a secular trend towards earlier puberty occurred in association with improvements in nutrition. The worldwide pandemic of childhood obesity has renewed interest in the relationship between body composition in childhood and the timing and tempo of puberty. Limited evidence suggests that earlier puberty is associated with a tendency towards central fat deposition; therefore, pubertal status needs to be carefully considered in the categorization of childhood and adolescent overweight and obesity. In the other direction, rapid early weight gain is associated with advanced puberty in both sexes, and a clear association exists between increasing BMI and earlier pubertal development in girls. Evidence in boys is less clear, with the majority of studies showing obesity to be associated with earlier puberty and voice break, although a subgroup of boys with obesity exhibits late puberty, perhaps as a variation of constitutional delay in growth and puberty. The possible mechanisms linking adiposity with pubertal timing are numerous, but leptin, adipocytokines and gut peptides are central players. Other possible mediators include genetic variation and environmental factors such as endocrine disrupting chemicals. This Review presents current evidence on this topic, highlighting inconsistencies and opportunities for future research.

  14. Sexual Anxiety and Eroticism Predict the Development of Sexual Problems in Youth With a History of Sexual Abuse

    OpenAIRE

    Simon, Valerie A.; Feiring, Candice

    2008-01-01

    Youth with confirmed histories of sexual abuse (N = 118) were followed longitudinally to examine associations between their initial sexual reactions to abuse and subsequent sexual functioning. Participants were interviewed at abuse discovery (ages 8 through 15) and again 1 and 6 years later. Eroticism and sexual anxiety emerged as distinct indices of abuse-specific sexual reactions and predicted subsequent sexual functioning. Eroticism was associated with indicators of heightened sexuality, i...

  15. History, Gender, Sexuality and Women's Development in the Global ...

    African Journals Online (AJOL)

    The global South-Africa in general and Nigeria in particular, is a continent grappling with forces which are anti-development, yet the continent is yearning for development at all levels of human endeavour. Some of these forces are the issue of gender, sexuality, women development, affirmative action, and gender ...

  16. Blooming Sexuality : A Biopsychosocial Perspective on Adolescent Romantic and Sexual Development

    NARCIS (Netherlands)

    Baams, L.|info:eu-repo/dai/nl/352220023

    2015-01-01

    The aim of this dissertation was to examine adolescent romantic and sexual development, in a biopsychosocial model, in which physical, psychological, and social contextual factors are considered. The findings of this dissertation show the importance of individual factors such as pubertal status and

  17. Identifying Adolescent Patients at Risk for Sexually Transmitted Infections: Development of a Brief Sexual Health Screening Survey.

    Science.gov (United States)

    Victor, Elizabeth C; Chung, Richard; Thompson, Robert J

    2015-08-01

    This study examined the association between survey responses to health behaviors, personality/psychosocial factors, and self-reported sexually transmitted infections (STIs) to create a brief survey to identify youth at risk for contracting STIs. Participants included 200 racially diverse 14- to 18-year-old patients from a pediatric primary care clinic. Two sexual behavior variables and one peer norm variable were used to differentiate subgroups of individuals at risk of contracting a STI based on reported history of STIs using probability (decision tree) analyses. These items, as well as sexual orientation and having ever had oral sex, were used to create a brief sexual health screening (BSHS) survey. Each point increase in total BSHS score was associated with exponential growth in the percentage of sexually active adolescents reporting STIs. Findings suggest that the BSHS could serve as a useful tool for clinicians to quickly and accurately detect sexual risk among adolescent patients. © The Author(s) 2014.

  18. The Developmental Association of Sexual Self-Concept with Sexual Behavior among Adolescent Women

    OpenAIRE

    Hensel, Devon J.; Fortenberry, J. Dennis; O’Sullivan, Lucia F.; Orr, Donald P.

    2010-01-01

    Developing a sexual self-concept is an important developmental task of adolescence; however, little empirical evidence describes this development, nor how these changes are related to development in sexual behavior. Using longitudinal cohort data from adolescent women, we invoked latent growth curve analysis to: (1) examine reciprocal development in sexual self-concept (sexual openness, sexual esteem and sexual anxiety) over a four year time frame; (2) describe the relationship of these traje...

  19. OPINIONS AND ATTITUDES OF PARENTS AND STUDENTS FOR SEXUAL DEVELOPMENT, SEXUAL BEHAVIOR AND GENDER IDENTITY OF PERSONS WITH AUTISM IN THE REPUBLIC OF MACEDONIA

    OpenAIRE

    MLADENOVSKA Bisera; TRAJKOVSKI Vladimir

    2015-01-01

    Persons with autism can experience severe issues during the puberty and adolescence resulting from the changes that occur in their body. People with autism are sexual beings. They have sexual needs and desires as other people. Sexual development is part of the overall development of their personality.The main objective of this research was to present sexual development, sexual behavior, and sexual identity among persons with autism. Furthermore, we determined the views and opinions of the par...

  20. Sex-specific growth in chicks of the sexually dimorphic Black-tailed Godwit

    NARCIS (Netherlands)

    Loonstra, A. H. Jelle; Verhoeven, Mo A.; Piersma, Theunis

    Sexual size dimorphism (SSD) is common in birds and has been linked to various selective forces. Nevertheless, the question of how and when the sexes start to differentiate from each other is poorly studied. This is a critical knowledge gap, as sex differences in growth may cause different responses

  1. Sexual and Religious Identity Development Among Adolescent and Emerging Adult Sexual Minorities

    OpenAIRE

    Dahl, Angie L.

    2011-01-01

    As the majority of Americans identify with a religious affiliation, the religious context is an important backdrop upon which identity development occurs. For lesbian, gay, bisexual, transgender, queer, questioning, and allied (LGBTQA) youths, the process of development may be complicated in a religious context due to denominational positions on same-sex sexuality. While recent researchers highlighted the importance of contextual influences on LGBTQA developmental processes, few studies have ...

  2. Racial Residential Segregation and Risky Sexual Behavior Among Non-Hispanic Blacks, National Survey of Family Growth, 2006 – 2010

    Science.gov (United States)

    Lutfi, Khaleeq; Trepka, Mary Jo; Fennie, Kristopher P.; Ibanez, Gladys; Gladwin, Hugh

    2015-01-01

    Sexually transmitted infections (STIs) including human immunodeficiency virus (HIV) have disproportionately affected the non-Hispanic black population in the United States. A person’s community can affect his or her STI risk by the community’s underlying prevalence of STIs, sexual networks, and social influences on individual behaviors. Racial residential segregation—the separation of racial groups in a residential context across physical environments—is a community factor that has been associated with negative health outcomes. The objective of this study was to examine if non-Hispanic blacks living in highly segregated areas were more likely to have risky sexual behavior. Demographic and sexual risk behavior data from non-Hispanic blacks aged 15 – 44 years participating in the National Survey of Family Growth were linked to Core-Based Statistical Area segregation data from the U.S. Census Bureau. Five dimensions measured racial residential segregation, each covering a different concept of spatial variation. Multilevel logistic regressions were performed to test the effect of each dimension on sexual risk behavior controlling for demographics and community poverty. Of the 3,643 participants, 588 (14.5%) reported risky sexual behavior as defined as two or more partners in the last 12 months and no consistent condom use. Multilevel analysis results show that racial residential segregation was associated with risky sexual behavior with the association being stronger for the centralization [aOR (95% CI)][2.07 (2.05 – 2.08)] and concentration [2.05 (2.03 – 2.07)] dimensions. This suggests risky sexual behavior is more strongly associated with neighborhoods with high concentrations of non-Hispanic blacks and an accumulation of non-Hispanic blacks in an urban core. Findings suggest racial residential segregation is associated with risky sexual behavior in non-Hispanic blacks 15 – 44 years of age with magnitudes varying by dimension. Incorporating

  3. Young women's perceived health and lifetime sexual experience: results from the national survey of family growth.

    Science.gov (United States)

    Hall, Kelli S; Moreau, Caroline; Trussell, James

    2012-05-01

    Sexuality is a component of health and well-being for all women, including adolescents. Yet relationships between young women's health perceptions and sexual behavior are unclear. We examined associations between perceived health and lifetime sexual experiences among young U.S. women. We used data from 4,413 young women ages 15-24 years in the National Survey of Family Growth, 2002-2008. Descriptive, bivariate, and multivariate statistics estimated relationships between categories of perceived health and types of lifetime sexual experience. A self-rated health Likert item and sexual history questions were administered with a computer-assisted survey instrument. Young women reported excellent (30%), very good (41%), good (23%), and fair-poor (6%) health. Sexual experiences included vaginal (64%), oral (64%), and anal (20%) sex. Negative experiences included involuntary sex (11%) and sexually transmitted infection (STI) history (8%). In multivariate logistic regression models, lower perceived health ("good" rather than "excellent") was positively associated with vaginal (odds ratio [OR] 1.5, confidence interval [CI] 1.1-2.1, P = 0.02), oral (OR 1.5, CI 1.1-2.1, P = 0.005), and anal (OR 1.4, CI 1.0-2.0, P = 0.03) sex. In models stratified by age, point estimates for vaginal (OR 1.8, CI 1.2-2.6, P = 0.002) and oral (OR 1.9, CI 1.4-2.6, P sexual experiences, point estimates were stable in models including STI history but statistically insignificant when including involuntary sexual experience. Other characteristics associated with sexual experiences varied by type of experience and included age, race/ethnicity, employment situation, poverty level, insurance status, childhood family situation, religious service participation, cohabitation/marital experience, and body mass index.   Further investigation is warranted to disentangle potentially negative relationships between perceived health (as well as response bias and more objective health outcomes), sociodemographic

  4. A parallel process growth mixture model of conduct problems and substance use with risky sexual behavior.

    Science.gov (United States)

    Wu, Johnny; Witkiewitz, Katie; McMahon, Robert J; Dodge, Kenneth A

    2010-10-01

    Conduct problems, substance use, and risky sexual behavior have been shown to coexist among adolescents, which may lead to significant health problems. The current study was designed to examine relations among these problem behaviors in a community sample of children at high risk for conduct disorder. A latent growth model of childhood conduct problems showed a decreasing trend from grades K to 5. During adolescence, four concurrent conduct problem and substance use trajectory classes were identified (high conduct problems and high substance use, increasing conduct problems and increasing substance use, minimal conduct problems and increasing substance use, and minimal conduct problems and minimal substance use) using a parallel process growth mixture model. Across all substances (tobacco, binge drinking, and marijuana use), higher levels of childhood conduct problems during kindergarten predicted a greater probability of classification into more problematic adolescent trajectory classes relative to less problematic classes. For tobacco and binge drinking models, increases in childhood conduct problems over time also predicted a greater probability of classification into more problematic classes. For all models, individuals classified into more problematic classes showed higher proportions of early sexual intercourse, infrequent condom use, receiving money for sexual services, and ever contracting an STD. Specifically, tobacco use and binge drinking during early adolescence predicted higher levels of sexual risk taking into late adolescence. Results highlight the importance of studying the conjoint relations among conduct problems, substance use, and risky sexual behavior in a unified model. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  5. Consanguinity and Disorders of Sexual Developments in the Sudan ...

    African Journals Online (AJOL)

    Background: Consanguinity is very common in the Sudanese society. There is a lack of studies on consanguinity and its impact on genetic diseases in Sudan. In this study we correlated Disorders of Sexual developments (DSDs), as an example of genetic conditions, in relation with consanguinity. Material and Methods: A ...

  6. Relationship of obesity and secondary sexual development in girls

    Directory of Open Access Journals (Sweden)

    Ida Ayu Sri Kusuma Dewi

    2010-03-01

    Conclusions This study established that mean age of secondary sexual development was younger in obese girl than non-obese group. Bone age range on obese girls was wider than non-obese girls. [Paediatr Indones. 2010;50:49-5].

  7. Developing adolescent sexuality in context: Relations with parents and peers

    NARCIS (Netherlands)

    Bongardt, D. van de

    2015-01-01

    In this dissertation it was investigated how various aspects of adolescents’ developing sexuality (behaviors, cognitions, emotions) are intertwined over time with adolescents’ relations with parents and peers. The overall goal of the six empirical studies, which utilized a multi-method approach

  8. Population, sexual and reproductive health, rights and sustainable development: forging a common agenda.

    Science.gov (United States)

    Newman, Karen; Fisher, Sarah; Mayhew, Susannah; Stephenson, Judith

    2014-05-01

    This article suggests that sexual and reproductive health and rights activists seeking to influence the post-2015 international development paradigm must work with sustainable development advocates concerned with a range of issues, including climate change, environmental issues, and food and water security, and that a way of building bridges with these communities is to demonstrate how sexual and reproductive health and rights are relevant for these issues. An understanding of population dynamics, including urbanization and migration, as well as population growth, can help to clarify these links. This article therefore suggests that whether or not sexual and reproductive health and rights activists can overcome resistance to discussing "population", become more knowledgeable about other sustainable development issues, and work with others in those fields to advance the global sustainable development agenda are crucial questions for the coming months. The article also contends that it is possible to care about population dynamics (including ageing and problems faced by countries with a high proportion of young people) and care about human rights at the same time. It expresses concern that, if sexual and reproductive health and rights advocates do not participate in the population dynamics discourse, the field will be left free for those for whom respecting and protecting rights may be less of a priority. Copyright © 2014 Reproductive Health Matters. Published by Elsevier Ltd. All rights reserved.

  9. Development and Refinement of a Targeted Sexual Risk Reduction Intervention for Women With a History of Childhood Sexual Abuse.

    Science.gov (United States)

    Senn, Theresa E; Braksmajer, Amy; Hutchins, Heidi; Carey, Michael P

    2017-11-01

    Childhood sexual abuse (CSA) is associated with sexual risk behavior in adulthood. Traditional sexual risk reduction interventions do not meet the unique needs of women who have been sexually abused. In the current paper, we describe the four-stage process we followed to develop and refine a targeted sexual risk reduction intervention for this population. First, initial quantitative work revealed that the intervention should address how maladaptive thoughts related to traumatic sexualization, trust, powerlessness, and guilt/shame (traumagenic dynamics constructs) influence current sexual behavior. Second, qualitative interviews with 10 women who reported a history of CSA ( M age = 34 years; 90% African American) as well as current sexual risk behavior provided support for targeting maladaptive thoughts associated with these traumagenic dynamics constructs. Third, based on the qualitative and quantitative results, we developed a 5-session, group-delivered intervention to address the maladaptive thoughts that occurred as a result of CSA, as well as the cognitive-behavioral determinants of sexual risk behavior. This intervention drew heavily on cognitive behavioral techniques to address cognitions associated with CSA and the links between these cognitions and current sexual risk behavior. Techniques from trauma-based therapies, as well as motivational techniques, were also incorporated into the intervention. Finally, we refined the intervention with 24 women ( M age = 33 years; 79% African American), and assessed feasibility and acceptability. These women reported high levels of satisfaction with the intervention. The resultant intervention is currently being evaluated in a small, randomized controlled trial.

  10. Density affects gametophyte growth and sexual expression of Osmunda cinnamomea (Osmundaceae: Pteridophyta).

    Science.gov (United States)

    Huang, Yao-moan; Chou, Hsueh-mei; Chiou, Wen-liang

    2004-08-01

    To understand how gametophyte densities affect the sexual expression and sizes of Osmunda cinnamomea and to provide information on the density of growth needed to favour successful reproduction, fresh spores were sown at various densities and subsequent gametophyte growth was studied. Spores were sown and cultured in the laboratory. Subsequent gameophytes at different population densities were sampled and their sexual expression and sizes were recorded. One-year-old multispore cultures of the fern O. cinnamomea demonstrated that population density affected gametophyte growth and sexual expression. As density increased, gametophytes became significantly smaller and more slender. Female and asexual gametophytes dominated in populations of low and high densities, respectively. At intermediate population densities, hermaphroditic and male gametophytes were dominant. Female gametophytes were larger than gametophytes of all other types. Hermaphroditic gametophytes were larger than male gametophytes, which were larger than asexual gametophytes. Large gametophytes were wide-cordate, whereas smaller ones tended to be narrow-spathulate. Gametophyte size of O. cinnamomea is negatively related to the population density, which significantly affects gametophytes' sexual expression. The presence of unisexual and bisexual gametophytes at intermediate densities indicates that both intergametophytic and intragametophytic selfing may occur.

  11. Homosexuality as a consequence of epigenetically canalized sexual development.

    Science.gov (United States)

    Rice, William R; Friberg, Urban; Gavrilets, Sergey

    2012-12-01

    Male and female homosexuality have substantial prevalence in humans. Pedigree and twin studies indicate that homosexuality has substantial heritability in both sexes, yet concordance between identical twins is low and molecular studies have failed to find associated DNA makers. This paradoxical pattern calls for an explanation. We use published data on fetal androgen signaling and gene regulation via nongenetic changes in DNA packaging (epigenetics) to develop a new model for homosexuality. It is well established that fetal androgen signaling strongly influences sexual development. We show that an unappreciated feature of this process is reduced androgen sensitivity in XX fetuses and enhanced sensitivity in XY fetuses, and that this difference is most feasibly mused by numerous sex-specific epigenetic modifications ("epi-marks") originating in embryonic stem cells. These epi-marks buffer XX fetuses from masculinization due to excess fetal androgen exposure and similarly buffer XY fetuses from androgen underexposure. Extant data indicates that individual epi-marks influence some but not other sexually dimorphic traits, vary in strength across individuals, and are produced during ontogeny and erased between generations. Those that escape erasure will steer development of the sexual phenotypes they influence in a gonad-discordant direction in opposite sex offspring, mosaically feminizing XY offspring and masculinizing XX offspring. Such sex-specific epi-marks are sexually antagonistic (SA-epi-marks) because they canalize sexual development in the parent that produced them, but contribute to gonad-trait discordances in opposite-sex offspring when unerased. In this model, homosexuality occurs when stronger-than-average SA-epi-marks (influencing sexual preference) from an opposite-sex parent escape erasure and are then paired with a weaker-than-average de novo sex-specific epi-marks produced in opposite-sex offspring. Our model predicts that homosexuality is part of a

  12. Cameroon - Fiscal policy for growth and development

    OpenAIRE

    World Bank

    2010-01-01

    Cameroon's growth achievement is disappointing and the country is not likely to meet most of the Millennium Development Goals (MDGs) on its current trajectory. Underemployment is extremely high, with risks of social unrest and instability. The fallout of the current global economic crisis is making more challenging the attainment of growth targets foreseen in the new Growth and Employment ...

  13. Population Growth and Economic and Social Development.

    Science.gov (United States)

    Clausen, A. W.

    1985-01-01

    All evidence shows that fast population growth slows development in the developing countries. It is the combination of social development and family planning that is so powerful in reducing fertility. Governments must act now. (RM)

  14. Growth and pubertal development in elite female rhythmic gymnasts.

    Science.gov (United States)

    Georgopoulos, N; Markou, K; Theodoropoulou, A; Paraskevopoulou, P; Varaki, L; Kazantzi, Z; Leglise, M; Vagenakis, A G

    1999-12-01

    Optimal growth depends upon both environmental and genetic factors. Among environmental factors that could alter growth and sexual maturation are stress and intensive physical training. The influence of these factors has been documented in a variety of sports, but there is limited information on rhythmic gymnasts, who have entirely different training and performance requirements. The study was conducted during the 13th European Championships in Patras, Greece, and included 255 female rhythmic gymnasts, aged 11-23 yr. The study included measurement of height and weight, assessment of breast and pubic hair development, estimation of body fat and skeletal maturation, and registration of menarcheal age and parental height. Gymnasts were taller than average height for age, with mean height above and mean weight below the 50th percentile. Actual height SD score was positively correlated to weight SD score (P rhythmic gymnasts, psychological and somatic efforts have profound effects on growth and sexual development. Despite these aberrations, adult height is not expected to be affected.

  15. [Does childhood obesity affect sexual development?].

    Science.gov (United States)

    Wagner, I V; Sergeyev, E; Dittrich, K; Gesing, J; Neef, M; Adler, M; Geserick, M; Pfäffle, R W; Körner, A; Kiess, W

    2013-04-01

    The process of pubertal development is only partly understood and is influenced by many different factors. During the twentieth century there was a general trend toward earlier pubertal development. Fat mass is thought to be a major inducer of puberty. Owing to the rising epidemic of childhood obesity, the relationship between body composition in children and the rate and timing of puberty needs to be investigated. Some studies suggest that central obesity is associated with an earlier onset of pubertal development. Rapid weight gain in early life is linked to advanced puberty in both sexes. A clear correlation exists between increasing body mass index (BMI) and earlier pubertal development in girls. In boys the data are controversial: The majority of studies propose that there is an earlier puberty and voice break in obese boys, but some studies show the opposite. There are several factors and mechanisms that seem to link obesity and puberty, for example, leptin, adipocytokines, and gut peptides. Important players include genetic variation and environmental factors (e.g., endocrine-disrupting chemicals). This article presents the latest studies and evidence on this topic, underlining the inconsistencies in the data and, therefore, the need for further research in this area.

  16. Understanding Early Sexual Development (For Parents)

    Science.gov (United States)

    ... get both in and out of the home. Preschool (Ages 3 to 5) By preschool, most kids have developed a strong sense of ... swim together. Issues that parents of elementary school-age kids might face include: Bad language. Children will pick up bad language and inappropriate ...

  17. High temperatures influence sexual development differentially in ...

    Indian Academy of Sciences (India)

    Samadhan Krushna Phuge

    2017-06-20

    Jun 20, 2017 ... These results suggest that high temperature probably acts through stress hormones and favours the small-sized sex. Keywords. Euphlyctis cyanophlyctis; gonadal development; metamorphosis; sex ratio; temperature-dependent sex determination. 1. Introduction. The process of gonadal sex determination ...

  18. High temperatures influence sexual development differentially in ...

    Indian Academy of Sciences (India)

    Although sex determination in amphibians is believed to be a genetic process, environmental factors such as temperatureare known to influence the sex differentiation and development. Extremely low and high temperatures influence gonadaldevelopment and sex ratio in amphibians but the mechanism of action is not ...

  19. Development of a Curriculum on Sexual Exploitation and Self-Protection for Handicapped Students.

    Science.gov (United States)

    Ryerson, Ellen; Sundem, Jennifer McGilvray

    1981-01-01

    To assist handicapped persons in preventing sexual exploitation, the Curriculum for Developing an Awareness of Sexual Exploitation and Teaching Self Protection Techniques was developed and pilot tested with 13 special education teachers in Seattle, Washington. (SB)

  20. The Role of Sexual Health Professionals in Developing a Shared Concept of Risky Sexual Behavior and HIV Transmission

    Science.gov (United States)

    Alexander, Kamila A.; Fannin, Ehriel F.; Baker, Jillian L.; Davis, Zupenda M.

    2015-01-01

    “Risky sexual behavior” accounts for the majority of new HIV infections regardless of gender, age, geographic location, or ethnicity. The phrase, however, refers to a relatively nebulous concept that hampers development of effective sexual health communication strategies. The purpose of this paper is to propose development of a shared conceptual understanding of “risky sexual behavior.” We reviewed multidisciplinary HIV/AIDS literature to identify definitions of risky sexual behavior. Both the linguistic components and the social mechanisms that contribute to the concept of risky sexual behaviors were noted. Risky sexual behavior was often defined in a subjective manner in the literature, even in the scientific research. We urge a paradigm shift to focus on explicit behaviors and the social context of those behaviors in determining HIV risk. We also propose a new definition that reduces individual biases and promotes a broader discussion of the degree of sexual risk across a diversity of behavioral contexts. Sexual health professionals can strengthen practice and research initiatives by operating from a concise working definition of risky sexual behavior that is broadly transferable and expands beyond a traditional focus on identity-based groups. PMID:26184496

  1. Being sexually attracted to minors : Sexual development, coping with forbidden feelings, and relieving sexual arousal in self-identified pedophiles

    NARCIS (Netherlands)

    Houtepen, J.A.B.M.; Sijtsema, J.J.; Bogaerts, S.

    2016-01-01

    This article aims to provide more insight into pedophilic attraction and risk and protective factors for offending in nonclinical pedophiles. Fifteen participants were interviewed about sexuality, coping, and sexual self-regulation. Many participants struggled with acknowledging pedophilic interest

  2. Adolescents' use of sexually explicit Internet material and their sexual attitudes and behavior: Parallel development and directional effects.

    Science.gov (United States)

    Doornwaard, Suzan M; Bickham, David S; Rich, Michael; ter Bogt, Tom F M; van den Eijnden, Regina J J M

    2015-10-01

    Although research has repeatedly demonstrated that adolescents' use of sexually explicit Internet material (SEIM) is related to their endorsement of permissive sexual attitudes and their experience with sexual behavior, it is not clear how linkages between these constructs unfold over time. This study combined 2 types of longitudinal modeling, mean-level development and cross-lagged panel modeling, to examine (a) developmental patterns in adolescents' SEIM use, permissive sexual attitudes, and experience with sexual behavior, as well as whether these developments are related; and (b) longitudinal directionality of associations between SEIM use on the 1 hand and permissive sexual attitudes and sexual behavior on the other hand. We used 4-wave longitudinal data from 1,132 7th through 10th grade Dutch adolescents (M(age) T1 = 13.95; 52.7% boys) and estimated multigroup models to test for moderation by gender. Mean-level developmental trajectories showed that boys occasionally and increasingly used SEIM over the 18-month study period, which co-occurred with increases in their permissive attitudes and their experience with sexual behavior. Cross-lagged panel models revealed unidirectional effects from boys' SEIM use on their subsequent endorsement of permissive attitudes, but no consistent directional effects between their SEIM use and sexual behavior. Girls showed a similar pattern of increases in experience with sexual behavior, but their SEIM use was consistently low and their endorsement of permissive sexual attitudes decreased over the 18-month study period. In contrast to boys, girls' SEIM use was not longitudinally related to their sexual attitudes and behavior. Theoretical and practical implications of these gender-specific findings are discussed. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

  3. Financial development, uncertainty and economic growth

    NARCIS (Netherlands)

    Lensink, B.W.

    By performing a cross-country growth regression for the 1970-1998 period this paper finds evidence for the fact that the impact of policy uncertainty on economic growth depends on the development of the financial sector. It appears that a higher level of financial development partly mitigates the

  4. Growth and nutrition effects on gilt development

    Science.gov (United States)

    The growth and development of gilts are a component of their lifetime potential for productivity. Growth and development affects not only their ability to reach puberty, they also likely affect their reproductive performance through later parities and their physical soundness as they age. Because of...

  5. Financial Development, Environmental Quality and Economic Growth

    Directory of Open Access Journals (Sweden)

    Shushu Li

    2015-07-01

    Full Text Available In this study, the relationships between financial development, environmental quality and economic growth are studied based on data from 102 countries over the period 1980–2010 using the generalized method of moments (GMM estimation. The econometric results show the following three basic conclusions: First, both financial development and environmental quality have a significant impact on economic growth and should be included in the production function of the economic growth model as important variables. Second, there is a significant and robust “inverted U-shaped” relationship between financial development and economic growth; with the improvement of the level of financial development, economic growth would first increase and then decrease, which is consistent with the results of previous studies. Third, there is also a significant and robust “inverted U-shaped” relationship between economic growth and carbon emissions, indicating that there exists a “critical point” at which achieving economic growth comes at the expense of environmental quality, and after passing the critical point, the deterioration of environmental quality will lead to a significant slowdown in economic growth. In addition, the econometric analysis in this paper also shows that there was a mutually promoting and strengthening relationship between financial development and environmental quality. Specifically, the degree of financial development can further strengthen the promoting effect of environmental quality on economic growth; meanwhile, an improvement in environmental quality can also strengthen the promoting effect of financial development on economic growth. Financial development and environmental quality could influence economic growth through strengthening the marginal product effects of capital and labor, which further indicates the that both financial and environmental factors play an important role in modern economic development.

  6. SEXUAL DEVELOPMENT, EDUCATION AND SEXUAL ABUSE OF PERSONS WITH DISABILITIES IN THE REPUBLIC OF MACEDONIA

    Directory of Open Access Journals (Sweden)

    Olivera RASHIKJ

    2009-11-01

    Full Text Available At social community level there are still myths and stereotypes, which refer to sexuality of the persons with disabilities. The most common wrong assumptions are those stating that persons with disabilities are asexual – long life children and the opposite ideas which state that persons with disabilities are sexually impulsive. The truth is that sexuality is an integral part of each life starting in the childhood and stretching throughout the whole life. The main goal of this master thesis, presented on 190 sheets, was to elaborate the characteristics of sexual development of persons with disabilities, more exactly of persons with mental retardation, vision impairments, auditive impairments and persons with physical impairments. Furthermore, to determine the degree and manner of acquired sex education and to make comparison in terms of prevalence and reasons for sexual abuse of persons with different types and degrees of disabilities, as well as to stress the possibilities for prevention.The sample of the research was consisted of 317 examinees separated in 6 groups and one control group. The first group included 98 examinees with mental retardation, out of which 36 at the age between 10 and 15 years from the Special Primary Schools “Idnina” and “Dr. Zlatan Sremac”, 29 examinees with mild mental retardation older than 15 years from the State Secondary School for Rehabilitation and Education “St. Naum Ohridski”, 33 examinees with moderate mental retardation no older than 10 years of age, from Institution for Rehabilitation of the Children and Youth – Topansko Pole. The second group included 25 persons with visual impairments from the Institution for Rehabilitation of Children and Youth with Visual Impairments “Dimitar Vlahov”, out of which 8 were at the age between 10 and 15 years and 17 examinees were older than 15 years. The third group included 19 examinees with auditive impairments at the age between 10 and 15 years from

  7. Development and Validation of the Sexual Contingent Self-Worth Scale.

    Science.gov (United States)

    Glowacka, Maria; Rosen, Natalie O; Vannier, Sarah; MacLellan, Margaret C

    2017-01-01

    Sexual contingent self-worth (CSW) refers to self-worth that is dependent on maintaining a sexual relationship, and has not been studied previously. This novel construct may have implications for sexual, relationship, and psychological well-being, because it could affect the cognitions, affect, and behaviors of individuals in sexual relationships. The purpose of this study was to develop the Sexual Contingent Self-Worth Scale and examine its reliability and validity in community samples. Two separate online studies (N = 329 and N = 282) included men and women who were in committed, sexually active relationships. The Sexual CSW Scale was adapted from a validated measure of relationship CSW. In Study 1, participants completed the Sexual CSW Scale, whereas in Study 2, participants also responded to standardized measures of related constructs. In addition, participants completed the Sexual CSW Scale again two weeks later in Study 2. Factor analysis yielded two subscales: (a) sexual CSW dependent on positive sexual events in the relationship and (b) sexual CSW dependent on negative sexual events. Results indicated good construct validity, incremental validity, internal consistency, and test-retest reliability for the Sexual CSW Scale. This research contributes to the fields of both CSW and sexuality by introducing a novel domain of CSW.

  8. Italy's growth and development plan

    International Nuclear Information System (INIS)

    2005-01-01

    To pursue and re launch the objectives of the Lisbon strategy for the development of the European Union, each country has drawn up an implementation plan that takes account of its own characteristics and situations [it

  9. The biomechanical basis of bone strength development during growth.

    Science.gov (United States)

    Kontulainen, Saija A; Hughes, Julie M; Macdonald, Heather M; Johnston, James D

    2007-01-01

    Understanding the development of the material composition and structure of bone during growth, both key determinants of bone strength, and identifying factors that regulate the development of these properties are important for developing effective lifestyle interventions to optimize peak bone strength. New imaging technologies provide the ability to measure estimates of both the material composition and structure of bone, and thus, estimates of whole bone strength. During childhood and adolescence, bone structure is altered by growth in length and width, which is associated with increases in mass, and alterations in tissue density. These processes lead to a bone with an optimal size, shape, and architecture to withstand the normal physiological loads imposed on it. Longitudinal bone growth is the result of endochondral ossification, a process that continues throughout childhood and rapidly increases during the adolescent growth spurt. Along the shaft, long bones continually grow in width, thus improving the resistance to bending forces by depositing new bone on the periosteal surface with simultaneous resorption on the endocortical surface. Sexual dimorphism in periosteal bone formation and endosteal bone resorption result in sex-specific differences in adult bone conformation. Changes in linear and periosteal growth are closely tied to changes in bone mass, with approximately one quarter of adult total body bone mineral accrued during the 2 years around the adolescent growth spurt. These structural and material changes are under mechanical regulation and influenced by the hormonal environment. Overall, bones must continually adapt their geometry and mass to withstand loads from increases in bone length, muscle mass and external forces during growth. However, the tempo, timing, and extent of such adaptations are also closely regulated by several systemic hormones.

  10. From Millennium Development Goals to post-2015 sustainable development: sexual and reproductive health and rights in an evolving aid environment.

    Science.gov (United States)

    Hill, Peter S; Huntington, Dale; Dodd, Rebecca; Buttsworth, Michael

    2013-11-01

    Using research from country case studies, this paper offers insights into the range of institutional and structural changes in development assistance between 2005 and 2011, and their impact on the inclusion of a sexual and reproductive health and rights agenda in national planning environments. At a global level during this period, donors supported more integrative modalities of aid - sector wide approaches, poverty reduction strategy papers, direct budgetary support - with greater use of economic frameworks in decision-making. The Millennium Development Goals brought heightened attention to maternal mortality, but at the expense of a broader sexual and reproductive health and rights agenda. Advocacy at the national planning level was not well linked to programme implementation; health officials were disadvantaged in economic arguments, and lacked financial and budgetary controls to ensure a connection between advocacy and action. With increasing competency in higher level planning processes, health officials are now refocusing the post-2015 development goals. If sexual and reproductive health and rights is to claim engagement across all its multiple elements, advocates need to link them to the key themes of sustainable development: inequalities in gender, education, growth and population, but also to urbanisation, migration, women in employment and climate change. Copyright © 2013 Reproductive Health Matters. Published by Elsevier Ltd. All rights reserved.

  11. Stages of growth in economic development

    Czech Academy of Sciences Publication Activity Database

    Kejak, Michal

    2003-01-01

    Roč. 27, č. 5 (2003), s. 771-800 ISSN 0165-1889 Institutional research plan: CEZ:AV0Z7085904 Keywords : growth * human capital * development Subject RIV: AH - Economics Impact factor: 0.690, year: 2003

  12. The white collar complex is involved in sexual development of Fusarium graminearum.

    Directory of Open Access Journals (Sweden)

    Hun Kim

    Full Text Available Sexual spores (ascospores of Fusarium graminearum, a homothallic ascomycetous fungus, are believed to be the primary inocula for epidemics of the diseases caused by this species in cereal crops. Based on the light requirement for the formation of fruiting bodies (perithecia of F. graminearum under laboratory conditions, we explored whether photoreceptors play an important role in sexual development. Here, we evaluated the roles of three genes encoding putative photoreceptors [a phytochrome gene (FgFph and two white collar genes (FgWc-1 and FgWc-2] during sexual development in F. graminearum. For functional analyses, we generated transgenic strains lacking one or two genes from the self-fertile Z3643 strain. Unlike the wild-type (WT and add-back strains, the single deletion strains (ΔFgWc-1 and ΔFgWc-2 produced fertile perithecia under constant light on complete medium (CM, an unfavorable medium for sexual development as well as on carrot agar (a perithecial induction condition. The expression of mating-type (MAT genes increased significantly in the gene deletion strains compared to the WT under both conditions. Deletion of FgFph had no significant effect on sexual development or MAT gene expression. In contrast, all of the deletion strains examined did not show significant changes in other traits such as hyphal growth, mycotoxin production, and virulence. A split luciferase assay confirmed the in vivo protein-protein interactions among three photoreceptors along with FgLaeA, a global regulator of secondary metabolism and fungal development. Introduction of an intact copy of the A. nidulans LreA and LreB genes, which are homologs of FgWc-1 and FgWc-2, into the ΔFgWc-1 and ΔFgWc-2 strains, respectively, failed to repress perithecia formation on CM in the gene deletion strains. Taken together, these results demonstrate that FgWc-1 and FgWc-2, two central components of the blue-light sensing system, negatively regulate sexual development in F

  13. Perpetration of Sexual Coercion and Victim of Sexual Coercion Scales: development and validation.

    Science.gov (United States)

    Mathes, Eugene W; McCoy, Jamie

    2011-04-01

    The purpose of this research was to create two scales, one to measure the tendency to perpetrate sexual coercion and one the tendency to be a victim of sexual coercion (Study 1), and to provide data validating the scales (Studies 2 and 3). Using the rational method of scale construction, two 13-item scales were constructed: the Perpetrator of Sexual Coercion Scale and the Victim of Sexual Coercion Scale. Construct validity (Study 2) was based on significant correlations with measures of engaging in promiscuous sex and abuse of alcohol. Support was found for the hypothesis (Study 3) that sexual coercion, being a victim of sexual coercion, alcohol abuse, and sexual promiscuity were associated with the pursuit of immediate pleasure through alcohol and sex.

  14. Developing a Practical Parenting Workshop: A Case Study in Family Sexual Communication

    Science.gov (United States)

    Croatt, Heidi S.

    2012-01-01

    This dissertation discusses the development and assessment of a parent intervention and training program. Out of concern for the sexual health of adolescents in the United States, both parents and researchers have called for programs assisting parents in the sexual education of their children. Encouraging sexual communication and increasing the…

  15. Differences in Psychological Distress and Esteem Based on Sexual Identity Development

    Science.gov (United States)

    Shepler, Dustin; Perrone-McGovern, Kristin

    2016-01-01

    A sample of 791 college students between the ages of 18 and 25 years were administered a series of measures to determine their sexual identity development status, global self-esteem, global psychological distress, sexual-esteem and sexual distress. As hypothesized, results indicated no significant difference in terms of psychological distress,…

  16. Empowering or oppressing? Development and exploration of the Enjoyment of Sexualization Scale.

    Science.gov (United States)

    Liss, Miriam; Erchull, Mindy J; Ramsey, Laura R

    2011-01-01

    Sexualization of girls and women in America is rampant and has many negative consequences. Women, however, often report enjoying being sexually admired by men. Given this paradox, it is unclear whether such enjoyment represents an authentic empowerment of women's sexuality or is related to traditional feminine norms and sexist beliefs. In Studies 1 and 2, the authors developed and tested the eight-item Enjoyment of Sexualization Scale (ESS). It had good reliability and was differentiated from related constructs including body surveillance, body shame, self-sexualizing behaviors, and appearance-contingent self-esteem. In Study 3, endorsement of traditional gender norms, endorsement of benevolent sexism, and endorsement of hostile sexism were all positively related to the ESS. Moreover, women who both enjoyed sexualization and engaged in self-objectification reported more negative eating attitudes. Overall, there was little support for positive effects of enjoying sexualization. The extent to which enjoying sexualization actually empowers women or contributes to their oppression is discussed.

  17. Financial Development, Growth and Equity in Brazil

    OpenAIRE

    Armando Castelar Pinheiro; Regis Bonelli

    2015-01-01

    Financial markets help to foster growth and productivity through their role in mobilizing savings to finance investment and production, selecting and monitoring investment projects, diversifying risks, and allowing investment and production to be carried out in the most productive scale and time frame. This paper examines the links between financial development, growth and equity. The focus is on the Brazilian case, but we also aim at contributing to a broader discussion on the role of financ...

  18. Development and Validation of the Sexual Abstinence Scale (SAS ...

    African Journals Online (AJOL)

    The Sexual Abstinence Scale (SAS) is designed to assess healthy sexual behaviour among adolescents as a way to reduce the incidence of HIV and other sexually transmitted diseases. This cross sectional study took place in two phases. The first phase comprised of 1030 adolescents randomly selected from senior ...

  19. Development of the Sexual Minority Adolescent Stress Inventory

    Directory of Open Access Journals (Sweden)

    Sheree M. Schrager

    2018-03-01

    Full Text Available Although construct measurement is critical to explanatory research and intervention efforts, rigorous measure development remains a notable challenge. For example, though the primary theoretical model for understanding health disparities among sexual minority (e.g., lesbian, gay, bisexual adolescents is minority stress theory, nearly all published studies of this population rely on minority stress measures with poor psychometric properties and development procedures. In response, we developed the Sexual Minority Adolescent Stress Inventory (SMASI with N = 346 diverse adolescents ages 14–17, using a comprehensive approach to de novo measure development designed to produce a measure with desirable psychometric properties. After exploratory factor analysis on 102 candidate items informed by a modified Delphi process, we applied item response theory techniques to the remaining 72 items. Discrimination and difficulty parameters and item characteristic curves were estimated overall, within each of 12 initially derived factors, and across demographic subgroups. Two items were removed for excessive discrimination and three were removed following reliability analysis. The measure demonstrated configural and scalar invariance for gender and age; a three-item factor was excluded for demonstrating substantial differences by sexual identity and race/ethnicity. The final 64-item measure comprised 11 subscales and demonstrated excellent overall (α = 0.98, subscale (α range 0.75–0.96, and test–retest (scale r > 0.99; subscale r range 0.89–0.99 reliabilities. Subscales represented a mix of proximal and distal stressors, including domains of internalized homonegativity, identity management, intersectionality, and negative expectancies (proximal and social marginalization, family rejection, homonegative climate, homonegative communication, negative disclosure experiences, religion, and work domains (distal. Thus, the SMASI development process illustrates

  20. Public Education and Growth in Developing Countries

    DEFF Research Database (Denmark)

    Schuppert, Christiane; Wirz, Nadja

    governments can invest in human capital to facilitate the adoption of new technologies invented abroad or, instead, focus on consumptive public spending. Although human capital is pivotal for growth, the model reveals that incentives to invest in public education vanish if a country is poorly endowed......Human capital plays a key role in fostering technology adoption, the major source of economic growth in developing countries. Consequently, enhancing the level of human capital should be a matter of public concern. The present paper studies public education incentives in an environment in which...... with human capital. Rather, governments of these poorly-endowed countries focus on consumptive public spending. As a result, while their better-endowed counterparts build up human capital thereby promoting technology adoption and growth, the growth process in poorly-endowed countries stagnates....

  1. Anxiety and Depressive Symptoms Among People Living with HIV and Childhood Sexual Abuse: The Role of Shame and Posttraumatic Growth.

    Science.gov (United States)

    Willie, Tiara C; Overstreet, Nicole M; Peasant, Courtney; Kershaw, Trace; Sikkema, Kathleen J; Hansen, Nathan B

    2016-08-01

    There is a critical need to examine protective and risk factors of anxiety and depressive symptoms among people living with HIV in order to improve quality of life. Structural equation modeling was used to examine the associations between HIV-related shame, sexual abuse-related shame, posttraumatic growth, and anxiety and depressive symptoms among a cohort of 225 heterosexual women and men who have sex with men (MSM) living with HIV who have experienced childhood sexual abuse (CSA). Higher sexual abuse-related shame was related to more anxiety and depressive symptoms for heterosexual women. Higher posttraumatic growth predicted less anxiety symptoms for only heterosexual women. Higher posttraumatic growth predicted less depressive symptoms for heterosexual women and MSM, but the magnitude of this effect was stronger for heterosexual women than MSM. Psychosocial interventions may need to be tailored to meet the specific needs of heterosexual women and MSM living with HIV and CSA.

  2. Endogenous growth theory and regional development policy

    Directory of Open Access Journals (Sweden)

    Cvetanović Slobodan

    2015-01-01

    Full Text Available The numerous versions of endogenous explanations of economic growth emphasize the importance of technological change driving forces, as well as the existence of appropriate institutional arrangements. Endogenous growth theory contributes to a better understanding of various experiences with long-term growth of countries and regions. It changes the key assumptions of the Neoclassical growth theory and participates in the modern regional development physiology explanation. Based on these conclusions, the paper: a explicates the most important theoretical postulates of the theory, b explains the most important factors of economic growth in the regions in light of the Endogenous growth theory messages and c emphasizes the key determinants of regional competitiveness which in our view is conceptually between the phenomena of micro- and macro-competitiveness and represents their necessary and unique connection. First of all, micro-competitiveness is transformed into a regional competitiveness; then regional competitiveness is transformed into a macro-competitiveness. In turn, macro - influences the microeconomic competitiveness, and the circle is closed. After that, the process starts over again.

  3. Disturbances of bone growth and development

    International Nuclear Information System (INIS)

    Ledesma-Medina, J.; Newman, B.; Oh, K.S.

    1988-01-01

    ''What is growth anyway? Can one talk about positive growth in childhood, neutral growth in maturity, and negative growth in old age? Our goal is to help promote normal positive growth in infants and children. To achieve this, we must be cognizant of the morphologic changes of both normal and abnormal bone formation as they are reflected in the radiographic image of the skeleton. The knowledge of the various causes and the pathophysiologic mechanisms of the disturbances of bone growth and development allows us to recognize the early radiographic manifestations. Endocrine and metabolic disorders affect the whole skeleton, but the early changes are best seen in the distal ends of the femurs, where growth rate is most rapid. In skeletal infections and in some vascular injuries two-or three-phase bone scintigraphy supercedes radiography early in the course of the disease. MRI has proved to be very helpful in the early detection of avascular bone necrosis, osteomyelitis, and tumor. Some benign bone tumors and many bone dysplasias have distinct and diagnostic radiographic findings that may preclude further studies. In constitutional diseases of bone, including chromosomal aberrations, skeletal surveys of the patient and all family members together with biochemical and cytogenetic studies are essential for both diagnosis and genetic counseling. Our role is to perform the least invasive and most informative diagnostic imaging modalities that corroborate the biochemical and histologic findings to establish the definitive diagnosis. Unrecognized, misdiagnosed, or improperly treated disturbance of bone growth can result in permanent deformity usually associated with disability. 116 references

  4. A Study of Myometrial Growth and Development.

    Science.gov (United States)

    Cramer, Stewart F; Oshri, Assaf; Heller, Debra S

    2015-10-01

    To evaluate myometrial growth and development. Thirty-five autopsy uteri, ranging from 10 weeks' gestation to age 18 years, acquired over 3 decades from 2 hospitals, were studied based on specimen availability, photographed for documentation, and reviewed at the end of the study. Most were embedded in toto, with 1 block and 1 slide per case. Some were immunostained for actin, CD10, MIB-1, and/or trichrome stain for collagen and muscle. Myometrial thickness was measured by ocular micrometry when sections were nontangential and analyzed by paired-sample t tests and bivariate linear regression. Two university-affiliated hospitals. From 20 to 34 weeks, lateral wall corpus thickness increased 6-fold, with a 4- to 6-fold perinatal burst of growth (P development. There was a pubertal burst of inframucosal myometaplasia. Myometaplasia accounted for most myometrial growth, especially in the perinatal and pubertal bursts of growth. Pressure effects, related to myometrial tone, appeared to affect myometrial development. True endocervix, with a fibrous wall and mucinous epithelium, appeared late in development. Copyright © 2015 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  5. Will inclusive growth succeed? | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2017-05-15

    May 15, 2017 ... Civil society, government, private sectors, and researchers must rally together towards such a promising framework. But who has heard about inclusive growth outside of international development circles? Let's continue to diversify the conversation and document what works and what doesn't to ensure that ...

  6. Genome-wide association study (GWAS for growth rate and age at sexual maturation in Atlantic salmon (Salmo salar.

    Directory of Open Access Journals (Sweden)

    Alejandro P Gutierrez

    Full Text Available Early sexual maturation is considered a serious drawback for Atlantic salmon aquaculture as it retards growth, increases production times and affects flesh quality. Although both growth and sexual maturation are thought to be complex processes controlled by several genetic and environmental factors, selection for these traits has been continuously accomplished since the beginning of Atlantic salmon selective breeding programs. In this genome-wide association study (GWAS we used a 6.5K single-nucleotide polymorphism (SNP array to genotype ∼ 480 individuals from the Cermaq Canada broodstock program and search for SNPs associated with growth and age at sexual maturation. Using a mixed model approach we identified markers showing a significant association with growth, grilsing (early sexual maturation and late sexual maturation. The most significant associations were found for grilsing, with markers located in Ssa10, Ssa02, Ssa13, Ssa25 and Ssa12, and for late maturation with markers located in Ssa28, Ssa01 and Ssa21. A lower level of association was detected with growth on Ssa13. Candidate genes, which were linked to these genetic markers, were identified and some of them show a direct relationship with developmental processes, especially for those in association with sexual maturation. However, the relatively low power to detect genetic markers associated with growth (days to 5 kg in this GWAS indicates the need to use a higher density SNP array in order to overcome the low levels of linkage disequilibrium observed in Atlantic salmon before the information can be incorporated into a selective breeding program.

  7. Genome-wide association study (GWAS) for growth rate and age at sexual maturation in Atlantic salmon (Salmo salar).

    Science.gov (United States)

    Gutierrez, Alejandro P; Yáñez, José M; Fukui, Steve; Swift, Bruce; Davidson, William S

    2015-01-01

    Early sexual maturation is considered a serious drawback for Atlantic salmon aquaculture as it retards growth, increases production times and affects flesh quality. Although both growth and sexual maturation are thought to be complex processes controlled by several genetic and environmental factors, selection for these traits has been continuously accomplished since the beginning of Atlantic salmon selective breeding programs. In this genome-wide association study (GWAS) we used a 6.5K single-nucleotide polymorphism (SNP) array to genotype ∼ 480 individuals from the Cermaq Canada broodstock program and search for SNPs associated with growth and age at sexual maturation. Using a mixed model approach we identified markers showing a significant association with growth, grilsing (early sexual maturation) and late sexual maturation. The most significant associations were found for grilsing, with markers located in Ssa10, Ssa02, Ssa13, Ssa25 and Ssa12, and for late maturation with markers located in Ssa28, Ssa01 and Ssa21. A lower level of association was detected with growth on Ssa13. Candidate genes, which were linked to these genetic markers, were identified and some of them show a direct relationship with developmental processes, especially for those in association with sexual maturation. However, the relatively low power to detect genetic markers associated with growth (days to 5 kg) in this GWAS indicates the need to use a higher density SNP array in order to overcome the low levels of linkage disequilibrium observed in Atlantic salmon before the information can be incorporated into a selective breeding program.

  8. Perceptions of Childhood Sexual Abuse Survivors: Development and Initial Validation of a New Scale to Measure Stereotypes of Adult Survivors of Childhood Sexual Abuse

    Science.gov (United States)

    Zafar, Sadia; Ross, Erin C.

    2013-01-01

    The Childhood Sexual Abuse Stereotypes Scale was developed to assess stereotypes of adult survivors of childhood sexual abuse. Scale items were derived from two studies that elicited cultural and personal beliefs about, and emotions experienced towards adult childhood sexual abuse survivors among university undergraduates. Two scales, Emotions and…

  9. Influence of ovariectomy on metabolic and endocrine parameters during sexual development in the female pig.

    Science.gov (United States)

    Prunier, A; Louveau, I

    1997-09-01

    During pubertal maturation, the increase in blood concentrations of sexual steroids is associated with a spurt in plasma IGF-I in primates, rats and cattle. However, data on the influence of sex steroids on plasma IGF-I during this physiological period are contradictory. Therefore, the present experiment was undertaken to understand better the relationships between pubertal development, energy metabolic regulation and the IGF-I/IGFBP system in crossbred gilts (Large White x Landrace). Circulating concentrations of hormones and metabolites were examined in ovariectomized (n = 6) and sham-operated females (n = 9) during sexual development. Surgery and first blood samplings were performed at 70 days of age. Growth curves were similar in ovariectomized and entire females. First oestrus and ovulation occurred between 178 and 209 days in entire gilts. From 84 days of age, plasma FSH concentration was lower in sham-operated than in ovariectomized gilts (P feedback exerted by ovarian secretions on the gonadotrophin axis in entire gilts. Preprandial concentration of plasma glucose was not influenced by age whereas plasma free fatty acids decreased with age (P gilts. Plasma IGF-I and 43-39 kDa IGFBP levels increased whereas plasma 34 kDa IGFBP decreased with age (P gilts (P > 0.1). This experiment shows that gonadal steroids are not involved or play only a minor role in the control of IGF-I and IGFBP plasma levels during pubertal development in the female pig.

  10. Experimental evidence of polymorphysm of sexual development in Capitella sp. B (Polychaeta: Capitellidae from Barcelona, Spain

    Directory of Open Access Journals (Sweden)

    Nuria Méndez

    2002-06-01

    Full Text Available The development and growth of Capitella sp. B obtained from Barcelona were studied under culture conditions. Trochophore and metatrochophore larvae hatched non-simultaneously (two release periods from single brood tubes. This is the first laboratory evidence of polymorphysm of sexual development in the Capitella capitata species-complex. During the first release period, only free swimming trochophores hatched. The females, still bearing larvae inside the brood tube, were transferred to another dish. After three days, ciliated metatrochophores hatched from 8.7% of the transferred broods. In a culture experiment, larvae maintained in sediment enriched with artificial food grew to immature and mature adults. In this condition, the larvae that hatched during the first release reached the immature adult stage, while the larvae derived from the second release became mature adults. Oogenesis was observed three times in one female from the second release, though no spawning and fertilization occurred under incubation with sib mature males. Two different sizes of coelomic oocytes were observed. Polymorphysm of sexual development is discussed as an advantageous reproductive strategy enhancing survival in organic enriched sediments.

  11. Sexual Dimorphism of Growth Hormone in the Hypothalamus: Regulation by Estradiol

    Science.gov (United States)

    Addison, Melisande L.

    2012-01-01

    GH is best known as an anterior pituitary hormone fundamental in regulating growth, differentiation, and metabolism. GH peptide and mRNA are also present in brain, in which their functions are less well known. Here we describe the distribution of GH neurons and fibers and sex differences in Gh mRNA in adult mouse brain. Cell bodies exhibiting GH immunoreactivity are distributed in many brain regions, particularly in the hypothalamus in which retrograde labeling suggests that some of these cells project to the median eminence. To determine whether Gh mRNA is sexual dimorphic, we carried out quantitative RT-PCR on microdissected brain nuclei. Ovary-intact mice had elevated Gh mRNA in the arcuate nucleus and medial preoptic area (MPOA) compared with gonad-intact males. In males, castration increased Gh mRNA in the MPOA, whereas ovariectomy decreased Gh mRNA in both regions. When gonadectomized adults of both sexes were treated with estradiol Gh mRNA increased in females but had no effect in castrated males. Tamoxifen was able to blunt the rise in Gh mRNA in response to estradiol in females. In addition, we found that estrogen receptor-α is coexpressed in GH neurons in the MPOA and arcuate nucleus. In summary, the findings reveal sexual dimorphisms in Gh gene expression in areas of the brain associated with reproduction and behavior. Interestingly, estradiol enhances Gh mRNA in females only, suggesting that multiple factors orchestrate this sexual dimorphism. PMID:22315455

  12. OPINIONS AND ATTITUDES OF PARENTS AND STUDENTS FOR SEXUAL DEVELOPMENT, SEXUAL BEHAVIOR AND GENDER IDENTITY OF PERSONS WITH AUTISM IN THE REPUBLIC OF MACEDONIA

    Directory of Open Access Journals (Sweden)

    Bisera MLADENOVSKA

    2010-04-01

    Full Text Available Persons with autism can experience severe issues during the puberty and adolescence resulting from the changes that occur in their body. People with autism are sexual beings. They have sexual needs and desires as other people. Sexual development is part of the overall development of their personality.The main objective of this research was to present sexual development, sexual behavior, and sexual identity among persons with autism. Furthermore, we determined the views and opinions of the parents and students, special educators and rehabilitators, about children with autism. Basic tasks of this research were: to determine whether persons with autism have a clear picture and concept of their sexuality, whether the parents discuss this topic with their children, whether and how persons with autism know what sex is, what is contraception, unwanted pregnancy, sexually transmitted diseases or intimate parts of the body, whether they show some kind of sexual behavior, and whether the parents and students should be educated regarding the sexual development, behavior, and sexual identity of persons with autism.The survey was conducted over a period of almost 3 months, which included 94 respondents.Obtained data was collected, grouped, tabled, and processed with the standard statistical program Microsoft Office Excel 2003, applying χ2 tests and Fisher's Еxact test. Statistical important difference was at the level of p<0.05.From the analysis and interpretation of the results, we can conclude that in Macedonian families and schools there is a very small extent or no existence of communication between the parents and professionals with persons with autism about sexual development, sexual behavior, and sexual identity. Persons with autism have very little or no general knowledge about sexuality.

  13. Development of rat female genital cortex and control of female puberty by sexual touch.

    Science.gov (United States)

    Lenschow, Constanze; Sigl-Glöckner, Johanna; Brecht, Michael

    2017-09-01

    Rat somatosensory cortex contains a large sexually monomorphic genital representation. Genital cortex undergoes an unusual 2-fold expansion during puberty. Here, we investigate genital cortex development and female rat sexual maturation. Ovariectomies and estradiol injections suggested sex hormones cause the pubertal genital cortex expansion but not its maintenance at adult size. Genital cortex expanded by thalamic afferents invading surrounding dysgranular cortex. Genital touch was a dominant factor driving female sexual maturation. Raising female rats in contact with adult males promoted genital cortex expansion, whereas contact to adult females or nontactile (audio-visual-olfactory) male cues did not. Genital touch imposed by human experimenters powerfully advanced female genital cortex development and sexual maturation. Long-term blocking of genital cortex by tetrodotoxin in pubescent females housed with males prevented genital cortex expansion and decelerated vaginal opening. Sex hormones, sexual experience, and neural activity shape genital cortex, which contributes to the puberty promoting effects of sexual touch.

  14. Development of rat female genital cortex and control of female puberty by sexual touch.

    Directory of Open Access Journals (Sweden)

    Constanze Lenschow

    2017-09-01

    Full Text Available Rat somatosensory cortex contains a large sexually monomorphic genital representation. Genital cortex undergoes an unusual 2-fold expansion during puberty. Here, we investigate genital cortex development and female rat sexual maturation. Ovariectomies and estradiol injections suggested sex hormones cause the pubertal genital cortex expansion but not its maintenance at adult size. Genital cortex expanded by thalamic afferents invading surrounding dysgranular cortex. Genital touch was a dominant factor driving female sexual maturation. Raising female rats in contact with adult males promoted genital cortex expansion, whereas contact to adult females or nontactile (audio-visual-olfactory male cues did not. Genital touch imposed by human experimenters powerfully advanced female genital cortex development and sexual maturation. Long-term blocking of genital cortex by tetrodotoxin in pubescent females housed with males prevented genital cortex expansion and decelerated vaginal opening. Sex hormones, sexual experience, and neural activity shape genital cortex, which contributes to the puberty promoting effects of sexual touch.

  15. Development of Romantic Relationships and Sexual Activity in Young Adults With Cerebral Palsy: A Longitudinal Study

    NARCIS (Netherlands)

    Wiegerink, D.J.; Stam, H.J.; Gorter, J.W.; Cohen-Kettenis, P.T.; Roebroeck, M.E.

    2010-01-01

    Objectives: To describe the development of romantic relationships and sexual activity of young adults with cerebral palsy (CP), to investigate whether this development is associated with demographic and physical characteristics, and to compare the sexual activity of this group with an

  16. On early starters and late bloomers: the development of sexual behavior in adolescence across personality types

    NARCIS (Netherlands)

    Baams, L.; Overbeek, G.; Dubas, J.S.; van Aken, M.A.G.

    2014-01-01

    Little is known about the relationship between personality and sexual development among mid-adolescents. In the current study, we used a person-centered approach to investigate the relation between personality types and the development of sexual behavior. We hypothesized that undercontrolling

  17. Disorders of sexual development and associated changes in the pituitary-gonadal axis in dogs.

    NARCIS (Netherlands)

    Buijtels, J.J.C.W.M.; de Gier, J.; Kooistra, H.S.; Grinwis, G.C.M.; Naan, E.C.; Zijlstra, C.; Okkens, A.C.

    2012-01-01

    Normal sexual differentiation depends on completion of chromosomal sex determination, gonadal differentiation, and development of the phenotypic sex. An irregularity in any of these three steps can lead to a disorder in sexual development (DSD). We examined nine dogs with DSD by abdominal

  18. Perceived realism moderates the relation between sexualized media consumption and permissive sexual attitudes in Dutch adolescents.

    Science.gov (United States)

    Baams, Laura; Overbeek, Geertjan; Dubas, Judith Semon; Doornwaard, Suzan M; Rommes, Els; van Aken, Marcel A G

    2015-04-01

    This study examined whether the development of sexualized media consumption and permissive sexual attitudes would be more strongly interrelated when adolescents perceived sexualized media images as highly realistic. We used data from a three-wave longitudinal sample of 444 Dutch adolescents aged 13-16 years at baseline. Results from parallel process latent growth modeling multigroup analyses showed that higher initial levels of sexualized media consumption were associated with higher initial level of permissive sexual attitudes. Moreover, increases of sexualized media consumption over time were associated with increases of permissive sexual attitudes over time. Considering the moderation by perceived realism, we found these effects only for those who perceived sexualized media as more realistic. Findings for male and female adolescents were similar except for the relations between initial levels and subsequent development. Among male adolescents who perceived sexualized media images to be realistic, higher initial levels of permissive sexual attitudes were related to subsequent less rapid development of sexualized media consumption. For male adolescents who perceived sexualized media to be less realistic, higher initial levels of sexualized media consumption were related to a subsequent less rapid development of permissive sexual attitudes. These relations were not found for female adolescents. Overall, our results suggest that, in male and female adolescents, those with a high level of perceived realism showed a correlated development of sexualized media consumption and permissive sexual attitudes. These findings point to a need for extended information on how to guide adolescents in interpreting and handling sexualized media in everyday life.

  19. Developments in judicial approaches to sexual and reproductive health.

    Science.gov (United States)

    Cook, Rebecca J

    2002-01-01

    This article reviews the jurisprudence on reproductive and sexual health of national and international tribunals. This review reveals a shift from controlling reproduction and sexuality through the use of criminal law to impose a moral order, to the use of administrative law to ensure availability of safe and effective services, and, finally, to the use of human rights to promote respect for human dignity. The conventional use of criminal law to prohibit provision of reproductive and sexual health services, underage sex, and relations between same-sex partners is waning. Due in part to research showing how criminal law harms reproductive health, an emerging judicial trend is toward the more pragmatic use of law to reduce the harm to health associated with sexuality and reproduction. Most recently, courts are recognizing that respect for individuals' needs to protect their reproductive and sexual health is a matter of social justice.

  20. Population growth and development: the Kenyan experience.

    Science.gov (United States)

    Nyamwange, M

    1995-01-01

    Rapid population growth in Kenya and high fertility impacts negatively on economic development. The growth and high fertility results in declines in gross national product, per capita food consumption, and land quality; a high dependency ratio; urban crowding; and inadequate health systems. East Africa has the highest crude birth rates in Africa, and Kenya has the highest birth rate of 54/1000 population in East Africa. The African crude death rate is 50% higher than the world average, but Kenya's death rate is the lowest in East Africa and comparable to North American and European death rates. Kenya has the highest rate of natural increase of about 4%. Population growth rates rose over the decades. Kenya's average population density is well above the sub-Saharan African average and much lower than very high density countries. Population is unequally distributed. Regional densities are widely divergent, and the highest densities in Western province are well above densities in Rwanda and Burundi. Urban growth has increased, as has migration to urban areas. Nairobi has 57% of urban population. Improved health and nutrition have contributed to increased life expectancy. The desired family size is large. The impact of demographic factors on economic conditions is evident in the decline in gross national product per capita growth to under 1% during 1972-88. A slight upswing occurred during 1988-93, but other crises are emerging. Food production has not kept pace with population growth. Production has been low due to serious land degradation, short fallow periods, and traditional farming practices. Population pressure has forced families to shift agriculture onto marginal lands, and desertification has increased. A growing proportion of the population is unemployed or underemployed. Population programs should address the underlying conditions for fertility decline.

  1. Social and economic growth of developing nations

    International Nuclear Information System (INIS)

    Gregersen, H.M.; Laarman, J.G.

    1989-01-01

    This paper reports on social and economic growth of developing nations. Trees and forests are often of immeasurable importance to developing countries of the world. To be of value, however, effective and efficient institutions, programs, and policies must be designed and focused on such resources. Forest economics and policy researchers can contribute much to such activities. To be most effective, forest economics research should be designed to improve understanding of social forestry, watershed management, and nontimber forest outputs; enhance ability to effectively address environmental consequences of forestry development; heighten skill in guiding development of industrial forestry enterprises; and improve effectiveness of international aid for forestry development. Guided by such strategic directions, forest economics research can contribute much to the economic and social well-being of developing nations

  2. Attitudes and Moral Development During a College Course on Human Sexuality

    OpenAIRE

    Galway, Mary Alison

    1998-01-01

    The goal of this research project was to understand better how classroom teaching, as purposeful social construction, can influence student attitudes in the direction of increased sensitivity to the diversity and complexity of issues involving human sexuality and individual choices. To develop this understanding, pre- and post-semester attitudes about the topics of gender, sexual orientation, sex education, and sexual coercion were gathered along with demographic information. Written end-of-c...

  3. Status epilepticus during early development disrupts sexual behavior in adult female rats: recovery with sexual experience.

    Science.gov (United States)

    Coria-Avila, Genaro Alfonso; Paredes-Ramos, Pedro; Galán, Ricardo; Herrera-Covarrubias, Deissy; López-Meraz, Maria-Leonor

    2014-05-01

    Female sexual behavior is sensitive to stress and diseases. Some studies have shown that status epilepticus (SE) can affect sexual proceptivity and receptivity in female rats and also increases reject responses towards males. However, epidemiologic studies indicate that SE is more frequent in young individuals. Herein, we assessed the effects of SE in infant females on their sexual behavior during adulthood. Thirteen-day-old (P13) rat pups received intraperitoneal injections of lithium chloride (3 mEq/kg). Twenty hours later, at P14, SE was induced by subcutaneous injection of pilocarpine hydrochloride (100 mg/kg s.c.). Control animals were given an equal volume of saline subcutaneously. The animals were weaned at P21 and, later in adulthood, were ovariectomized and hormone-primed with estradiol+progesterone, and their sexual behavior assessed during 4 separate trials of 30 min each with a stud male. Our results indicate that proceptive behaviors (solicitations and hops and darts) were impaired during the first trial, but no alterations were observed for receptivity and attractivity. By trial 3, all SE females displayed normal proceptivity. These results indicate that SE in infancy readily affects proceptivity in a reversible manner. We discuss the role of sexual experience in recovery. Copyright © 2014 Elsevier Inc. All rights reserved.

  4. Post-larval development and sexual dimorphism of the spider crab Maja brachydactyla (Brachyura: Majidae

    Directory of Open Access Journals (Sweden)

    Guillermo Guerao

    2009-12-01

    Full Text Available The post-larval development of the majid crab Maja brachydactyla Balss, 1922 was studied using laboratory-reared larvae obtained from adult individuals collected in the NE Atlantic. The morphology of the first juvenile stage is described in detail, while the most relevant morphological changes and sexual differentiation are highlighted for subsequent juvenile stages, until juvenile 8. The characteristic carapace spines of the adult phase are present in the first juvenile stage, though with great differences in the degree of development and relative size. The carapace shows a high length/weight ratio, which becomes similar to that of adults at stage 7-8. Males and females can be distinguished from juvenile stage 4, based on sexual dimorphism in the pleopods and the presence of gonopores. In addition, the allometric growth of the pleon is sex-dependent from juvenile stage 4, with females showing a positive allometry (b=1.23 and males an isometric allometry (b=1.02.

  5. Growth models and analysis of development

    Energy Technology Data Exchange (ETDEWEB)

    Mathur, G.

    1979-10-01

    This paper deals with remnants of neoclassical elements in Keynesian and post-Keynesian thought, and attempts to demonstrate that the elimination of these elements from our modes of thinking would not impoverish economic analysis as a means of solving real problems. In the Keynesian analysis the causation from investment to savings is exhibited in terms of income determination. When put in terms of a capital-theory model, the vector of savings is represented in two ways: real savings and counterpart real savings. The former coincides with the investment vector and the latter with the vector of consumption goods foregone for diverting resources towards equipment making. Thus the Keynesian causation in capital theory terms makes the concept of national savings as an independent variable redudant. The Robinsonian causation in a golden age with full employment and its reversal of direction in a steady state with non-employment are then considered. But in each of these, variables like rate of savings and output/capital ratio are found to be dormant variables. They are termed as null variables which, being of no account in both full-employment and unemployment situations, could, without loss, be deleted from the repertory of analytical tools. The Harrod formula of warranted rate of growth, when put in causal form, thus becomes a redundant portion of economics of growth. The real determinants of the growth rate and real wage rate on which the analysis of growth or of development should be based, are also depicted.

  6. Development and Validation of the Juvenile Sexual Offense Recidivism Risk Assessment Tool-II.

    Science.gov (United States)

    Epperson, Douglas L; Ralston, Christopher A

    2015-12-01

    This article describes the development and initial validation of the Juvenile Sexual Offense Recidivism Risk Assessment Tool-II (JSORRAT-II). Potential predictor variables were extracted from case file information for an exhaustive sample of 636 juveniles in Utah who sexually offended between 1990 and 1992. Simultaneous and hierarchical logistic regression analyses were used to identify the group of variables that was most predictive of subsequent juvenile sexual recidivism. A simple categorical scoring system was applied to these variables without meaningful loss of accuracy in the development sample for any sexual (area under the curve [AUC] = .89) and sexually violent (AUC = .89) juvenile recidivism. The JSORRAT-II was cross-validated on an exhaustive sample of 566 juveniles who had sexually offended in Utah in 1996 and 1997. Reliability of scoring the tool across five coders was quite high (intraclass correlation coefficient [ICC] = .96). Relative to the development sample, however, there was considerable shrinkage in the indices of predictive accuracy for any sexual (AUC = .65) and sexually violent (AUC = .65) juvenile recidivism. The reduced level of accuracy was not explained by severity of the index sexual offense, time at risk, or missing data. Capitalization on chance and other explanations for the possible reduction in predictive accuracy are explored, and potential uses and limitations of the tool are discussed. © The Author(s) 2014.

  7. Factors of early trauma in the development of sexual anomalies in men

    Directory of Open Access Journals (Sweden)

    Novoselova M.L.

    2014-09-01

    Full Text Available According to the activities of the Investigative Committee of the Russian Federation, in 2013 reports have been published on investigations of sexual offenses (Article 131 and 132 of the Criminal Code at 10,228 cases. [12] In 2002, 8117 cases were investigated on these articles. [3] During the decade, the number of such offenses increased by more than 20 percent. Increasing the number of sexual offenses, their frequency and risk of relapse necessitated studying the problems of people with sexual disorders. But, in spite of numerous studies, currently not all subjects in this sphere have received the same attention. The problem of sexual assault has been relatively recently considered with the use of modern achievements of psychiatry and sexuality. In this regard, the influence of factors such as early trauma is currently still poorly understood. Our paper is devoted to the study of early trauma factors and their role in the development of sexual anomalies in men. The article contains a review of contemporary Russian and foreign literature on this topic. We also carried out an analytical and theoretical study of cases of subjects who have committed crimes of a sexual nature. This review helped to assess the role of factors of early trauma and showed how these factors can influence the development of various sexual abnormalities. In addition, we revealed the main biologically conditioned factors of early trauma and traced their influence on the development of sexual paraphilias.

  8. Secondary Traumatic Stress and Adjustment in Therapists Who Work with Sexual Violence Survivors: The Moderating Role of Posttraumatic Growth

    Science.gov (United States)

    Samios, Christina; Rodzik, Amber K.; Abel, Lisa M.

    2012-01-01

    Due to their secondary exposure to the traumatic events disclosed by clients, therapists who work with sexual violence survivors are at risk of experiencing secondary traumatic stress. We examined whether the negative effects of secondary traumatic stress on therapist adjustment would be buffered by posttraumatic growth. Sixty-one therapists who…

  9. Population growth and sustainable development in China.

    Science.gov (United States)

    Gui, S

    1998-12-01

    This article identifies the adverse impacts of population growth in China and offers suggestions for attaining sustainable development. Although China has below replacement level fertility, population will continue to increase. Chinese demographers project that the total fertility rate will average 2.1 each year until 2010, 2.1 until 2050, or 1.88 until 2010 and 1.6 during 2010-2050 under high, medium, and low variants, respectively. Total population would number 1.69 billion, 1.50 billion, or 1.46 billion under various projections, respectively, by 2050. Continued growth is expected to seriously slow economic development, to hinder improvements in the quality of and full use of human resources, to depress increases in per-capita economic development levels, and to impact on reasonable use of resources and environmental protection. The averting of 5 million births would save 35.5 billion yuan. Population growth has reduced the per-capita share of cultivated land from 0.19 to 0.08 hectares during 1952-95. There are about 150-190 million surplus rural laborers. Registered unemployment in cities was 3.1% in 1997. 11.5 million were laid-off workers. The working-age population will exceed 900 million during 2007-26. China's gross national product (GNP) was the 8th highest in the world in 1990, but its per-capita GNP was in 100th place. China's abundant natural resources are seriously reduced when population is considered. Environmental damage is already evident. Population growth needs to be controlled through family planning, an old-age social security program, and long-term population policies. Society needs healthier births and childbearing and better educated children.

  10. Attenuation of cortisol across development for victims of sexual abuse.

    Science.gov (United States)

    Trickett, Penelope K; Noll, Jennie G; Susman, Elizabeth J; Shenk, Chad E; Putnam, Frank W

    2010-01-01

    Inconsistencies exist in literature examining hypothalamic-pituitary-adrenal (HPA) axis activity in children and adults who have experienced childhood abuse. Hence, the extent and manner to which childhood abuse may disrupt HPA axis development is largely unknown. To address these inconsistencies, the developmental course of nonstress cortisol in a long-term longitudinal study was assessed at six time points from childhood through adolescence and into young adulthood to determine whether childhood abuse results in disrupted cortisol activity. Nonstress, morning cortisol was measured in 84 females with confirmed familial sexual abuse and 89 nonabused, comparison females. Although dynamically controlling for co-occurring depression and anxiety, hierarchical linear modeling (HLM) showed that relative to comparison females, the linear trend for abused females was significantly less steep when cortisol was examined across development from age 6 to age 30, t (1, 180) = -2.55, p cortisol activity starting in adolescence with significantly lower levels of cortisol by early adulthood, F (1, 162) = 4.78, p cortisol activity was initially significantly higher, t (1, 425) = 2.18, p cortisol hyposecretion subsequent to a period of heightened secretion.

  11. Sexual maturity in growing dinosaurs does not fit reptilian growth models.

    Science.gov (United States)

    Lee, Andrew H; Werning, Sarah

    2008-01-15

    Recent histological studies suggest relatively rapid growth in dinosaurs. However, the timing of reproductive maturity (RM) in dinosaurs is poorly known because unambiguous indicators of RM are rare. One exception is medullary bone (MB), which is an ephemeral bony tissue that forms before ovulation in the marrow cavities of birds as a calcium source for eggshelling. Recently, MB also was described in a single specimen of the saurischian dinosaur Tyrannosaurus rex. Here, we report two other occurrences of MB: in another saurischian dinosaur, Allosaurus, and in the ornithischian dinosaur Tenontosaurus. We show by counting lines of arrested growth and performing growth curve reconstructions that Tenontosaurus, Allosaurus, and Tyrannosaurus were reproductively mature by 8, 10, and 18 years, respectively. RM in these dinosaurs coincided with a transition from growth acceleration to deceleration. It also far precedes predictions based on the growth rates of living reptiles scaled to similar size. Despite relatively rapid growth, dinosaurs were similar to reptiles in that RM developed before reaching asymptotic size. However, this reproductive strategy also occurs in medium- to large-sized mammals and correlates with a strategy of prolonged multiyear growth. RM in actively growing individuals suggests that these dinosaurs were born relatively precocial and experienced high adult mortality. The origin of the modern avian reproductive strategy in ornithuran birds likely coincided with their extreme elevations in growth rate and truncations to growth duration.

  12. Development of a measure of college students' adherence to religious doctrine concerning sexual behavior.

    Science.gov (United States)

    Victor, Elizabeth C; Bowman, Hilary; Thompson, Robert J

    2015-01-01

    The authors developed a 14-item measure of adherence to religious doctrine concerning sexual behavior (ARDSB). The ARDSB psychometric properties were investigated to better understand religious motivations associated with changes in sexual behavior that may provide support for sexual health promotion and prevention programs. Four hundred eighty-three undergraduates aged 18 to 26. Data were collected from an online survey during the 2012-2013 academic school year. Principle components factor analysis identified 2 factors: reasons to break religious doctrine and reasons to adhere to religious doctrine concerning sexual behavior. The subscales had good internal consistency. Correlations, t tests, and analyses of variance of the subscales with measures of intrinsic and extrinsic religiosity and self-reported sexual behavior and risk provide support for concurrent validity. The ARDSB could be employed as a measure to better understand sexual behavior; it is inexpensive and relatively easy to employ in both research and campus ministry settings.

  13. [Research advances in the effects of environmental factors on the growth and development of Aurelia spp].

    Science.gov (United States)

    Wang, Jian-Yan; Yu, Zhi-Gang; Zhen, Yu; Mi, Tie-Zhu; Yao, Qing-Zhen; Wang, Guo-Shan

    2012-11-01

    Aurelia spp. is a cosmopolitan coastal species, and also, one dominant species of large jellyfish in the coastal waters of China. In recent years, Aurelia spp. bloom events occur frequently in the world, causing severe damage to marine ecosystems, coastal economy, and society development. Aurelia spp. has a complicated life history comprising a benthic asexually-reproducing polyp generation and a sexually-reproducing medusa generation, and various vegetative reproduction (budding, strobilation, and podocyst production) and sexual reproduction. Surrounding physical and biological factors affect each growth stage of Aurelia spp., especially the juvenile stage of planktonic-benthic life cycle, which has major effect on the population dynamics of Aurelia spp. This paper reviewed the research advances in the effects of environmental factors on Aurelia spp. at its different growth and development stages, and discussed some problems worthy of further study, aimed to provide useful reference for the research of the key factors controlling the jellyfish blooms in coastal waters of China.

  14. Sustainable development, demography and sexual and reproductive health: inseparable linkages and their policy implications.

    Science.gov (United States)

    Herrmann, Michael

    2014-05-01

    The greatest challenge today is to meet the needs of current and future generations, of a large and growing world population, without imposing catastrophic pressures on the natural environment. Meeting this challenge depends on decisive policy changes in three areas: more inclusive economic growth, greener economic growth, and population policies. This article focuses on efforts to address and harness demographic changes for sustainable development, which are largely outside the purview of the current debate. Efforts to this end must be based on the recognition that demographic changes are the cumulative result of individual choices and opportunities, and that demographic changes are best addressed through policies that enlarge these choices and opportunities, with a focus on ensuring unrestricted and universal access to sexual and reproductive health information and services, empowering women to fully participate in social, economic and political life, and investing in the education of the younger generation beyond the primary level. The article provides a strong argument for why the Programme of Action that was agreed at the International Conference on Population and Development (ICPD) 20 years ago continues to hold important implications and lessons for the formulation of the post-2015 development agenda, which is expected to supersede the Millennium Development Goals (MDGs). Copyright © 2014 Reproductive Health Matters. Published by Elsevier Ltd. All rights reserved.

  15. Sexual orientation and gender identity: developments in EU law

    Directory of Open Access Journals (Sweden)

    Evangelia (Lilian Tsourdi

    2013-04-01

    Full Text Available The amended version of the EU Qualification Directive, adopted in2011, marks further progress in ensuring LGBTI applicants’ rightsby explicitly adding gender identity alongside sexual orientation as acause of persecution.

  16. Childhood Sexual Abuse, Stigmatization, Internalizing Symptoms, and the Development of Sexual Difficulties and Dating Aggression

    Science.gov (United States)

    Feiring, Candice; Simon, Valerie A.; Cleland, Charles M.

    2009-01-01

    Potential pathways from childhood sexual abuse (CSA) to subsequent romantic intimacy problems were examined in a prospective longitudinal study of 160 ethnically diverse youth with confirmed CSA histories. Participants were interviewed at the time of abuse discovery, when they were 8-15 years of age, and again 1-6 years later. Stigmatization…

  17. Exploring the Sexual Development Experiences of Black Bisexual Male Adolescents Over Time.

    Science.gov (United States)

    Morgan, Anthony; Saunders, Brianna; Dodge, Brian; Harper, Gary; Arrington Sanders, Renata

    2018-01-03

    Scant research has sought to explore the development of dimensions of sexual orientation among Black bisexual male adolescents (BBMA). Understanding how sexual attractions, behaviors, and identities evolve among BBMA over time is crucial to understanding the most appropriate support strategies to provide during this developmental period. We sought to understand and describe the sexual orientation development experiences in a sample of BBMA over the course of 1 year. We further sought to understand the sociocontextual factors that may play a role during this development process. Fifteen BBMA, aged 15-19 years, were interviewed about sexual debut experiences (baseline) and were re-interviewed three times over a 1-year period about sexual attractions, behaviors, and identity at each follow-up point. A three-person team used inductive open coding to analyze each participant's data set. The mean Kinsey scale score for the sample was 2.93 (SD = 1.2) most closely translating to "heterosexual/gay-equally." A case study analysis was used to identify themes related to sexual attractions, behavior, and identity over time, within and across participants. Among the sample of young men, two unique groups were identified based on self-reported sexual identity and experiences of same- and other-sex sexual attractions and behaviors over time. The first group consisted of seven young men who consistently described their sexual identity as bisexual from baseline to the final follow-up. These young men also described similar experiences related to same- and other-sex sexual and romantic attractions and more consistently described same- and other-sex sexual behaviors. The second group consisted of eight young men that described changing sexual identity and same- and other-sex sexual romantic attractions over time. Participants described sociocontextual factors such as religion, masculinity, and homophobia played during their development. Findings from this study underscore the

  18. Sexual dimorphism in cortisol secretion starts after age 10 in healthy children: urinary cortisol metabolite excretion rates during growth.

    Science.gov (United States)

    Wudy, Stefan A; Hartmann, Michaela F; Remer, Thomas

    2007-10-01

    Detailed data on the physiological pattern of adrenocortical activity during normal growth are lacking. An established method to determine adrenocortical glucocorticoid secretion is the measurement of 24-h excretion rates of major urinary cortisol metabolites (C21). To test the hypothesis that the frequently reported higher cortisol secretion in men than in women develops during puberty, we examined C21 together with excretions of combined urinary free and conjugated cortisol (F(comb)) in 400 healthy boys and girls aged 3-18 yr using GC-MS. Daily excretion rates of C21, F(comb), and body surface area (BSA)-corrected F(comb) significantly increased with age in both sexes. In contrast, C21/BSA (microgxm(-2).day(-1)) declined from the age of 3-4 yr to 7-8 yr in boys and girls (P activity (allotetrahydrocortisol/tetrahydrocortisol) in females compared with males. Our results demonstrate dynamic changes in adrenocortical activity in healthy children resulting in an emerging sexual dimorphism in cortisol secretion after age 11. The latter can be explained, at least partly, by diverging 5alpha-reductase activities in boys and girls. F(comb), a frequently analyzed GC-MS parameter, proved not to reflect dynamic changes in cortisol secretion. In conclusion, the varying metabolic need for cortisol during normal growth may have implications for future improvements in glucocorticoid replacement therapy.

  19. Assessing the Sexual Knowledge of Women in Secure Settings: The Development of a New Screening Measure

    Science.gov (United States)

    Long, Clive G.; Krawczyk, Kirsten M.; Kenworthy, Nathalie E.

    2013-01-01

    Little research has been published on the need for sexual education for women in secure psychiatric facilities when patients present with a combination of learning disability, mental illness and personality disorder. The development of a brief, feasible, gender-speci?c sexual knowledge questionnaire is described, which has

  20. Sociosexual Identity Development and Sexual Risk Taking of Acculturating Collegiate Gay and Bisexual Men

    Science.gov (United States)

    Wilkerson, J. Michael; Brooks, Ann K.; Ross, Michael W.

    2010-01-01

    How collegiate gay and bisexual men acquire a sociosexual identity appears to affect their sexual health. Analysis of interview data from 25 self-identified collegiate gay or bisexual men resulted in the development of a collective sexual script for men acquiring a sociosexual identity. Changes in an individual's acting out of a cultural scenario…

  1. Positive Youth Development Interventions Impacting the Sexual Health of Young Minority Adolescents: A Systematic Review

    Science.gov (United States)

    Harris, LaNita W.; Cheney, Marshall K.

    2018-01-01

    A systematic literature review was conducted to assess the utility of Positive Youth Development (PYD) concepts in promoting positive sexual health behaviors in young minority adolescents (n = 12 studies). Interventions reported significant associations between PYD-focused interventions and ever having sex, sexual partners in the last 30 days,…

  2. Retrospective Recall of Sexual Orientation Identity Development among Gay, Lesbian, and Bisexual Adults

    Science.gov (United States)

    Calzo, Jerel P.; Antonucci, Toni C.; Mays, Vickie M.; Cochran, Susan D.

    2011-01-01

    Although recent attention has focused on the likelihood that contemporary sexual minority youth (i.e., gay, lesbian, bisexual [GLB]) are "coming out" at younger ages, few studies have examined whether early sexual orientation identity development is also present in older GLB cohorts. We analyzed retrospective data on the timing of sexual…

  3. Developing a Scale of Perception of Sexual Abuse in Youth Sports (SPSAYS)

    Science.gov (United States)

    Baker, Thomas A., III.; Byon, Kevin K.

    2014-01-01

    A scale was developed to measure perceptions of sexual abuse in youth sports by assessing (a) the perceived prevalence of sexual abuse committed by pedophilic youth sport coaches, (b) the perceived likelihood that a coach is a pedophile, (c) perceptions on how youth sport organizations should manage the risk of pedophilia, and (d) media influence…

  4. Effect of zeranol on sexual development of crossbred bulls.

    Science.gov (United States)

    Godfrey, R W; Randel, R D; Rouquette, F M

    1989-07-01

    Three groups of 1/2 Simmental X 1/4 Brahman X 1/4 Hereford bull calves were used during two different years to study effects of zeranol on sexual development. At 154 d of age, half the calves were implanted with 36 mg zeranol and half, not implanted, served as controls. Implanted calves were reimplanted at 90-d intervals throughout the trial (9 mo) each year. Trial 1 was conducted with 24 calves and Trial 2 was conducted the following year with 10 bulls. Twenty-four days after weaning (200 d of age) and at 28-d intervals thereafter, bulls in drylot in Trial 1 were weighted, scrotal circumference (SC) was measured and an ejaculate of semen was collected by electroejaculation to determine puberty. At these times, bulls were given 200 micrograms of GnRH i.m. and blood was collected at 0, 1, 2, 3, 4 and 5 h after GnRH. Serum concentrations of LH and testosterone (TEST) were determined. At slaughter, testis weight, length and circumference and pubertal status were recorded. Bulls implanted with zeranol had smaller SC than control bulls during the entire 9-mo period (P less than .0001). More control bulls reached puberty than did implanted bulls (82.4 vs 23.5%, respectively; P less than .001). Control bulls had larger testis measurements at slaughter (P less than .0001). Implants did not alter total weight gain or ADG (P greater than .10).(ABSTRACT TRUNCATED AT 250 WORDS)

  5. 'Popping the clutch': novel mechanisms regulating sexual development in Cryptococcus neoformans.

    Science.gov (United States)

    Park, Yoon-Dong; Williamson, Peter R

    2012-06-01

    Sexual reproduction in fungal pathogens such as Cryptococcus provides natural selection and adaptation of the organisms to environmental conditions by allowing beneficial mutations to spread. However, successful mating in these fungi requires a time-critical induction of signaling pheromones when appropriate partners become available. Recently, it has been shown that the fungus uses the transcriptional equivalent of the racing technique: 'popping the clutch'-pushing in the clutch pedal, putting the car in gear, revving with the gas pedal, and then dropping the clutch pedal to accelerate rapidly. In the same way, Cryptococcus during vegetative growth constitutively matches a high rate of pheromone synthesis with a high rate of degradation to produce repressed levels of transcript. Then, when mating is required, the fungus drops the degradative machinery, resulting in a rapid induction of the pheromone. Pairing with this novel regulatory cycle is a host of mitogen-activated protein kinase cascades, cyclic AMP-dependent, and calcium-calcineurin signaling pathways that maintain these high rates of pheromone synthesis and prime downstream pathways for an effective mating response. The intersection of a number of virulence-associated traits with sexual development such as the synthesis of an immune-disruptive laccase as well as a protective polysaccharide capsule makes these rapid regulatory strategies a formidable foe in the battle against human disease.

  6. Disturbance of physical growth and development

    International Nuclear Information System (INIS)

    Nakamura, Nori; Akiyama, Mitoshi

    1992-01-01

    It has been thought that physical growth, such as height, weight, sitting height, chest circumference, and head circumference, was retarded among A-bomb survivors exposed in childhood. In this paper, physical growth and development among A-bomb survivors are discussed in the context of exposure doses estimated by T65D. The 1966-1968 survey for Hiroshima's survivors has shown that there was no consistent tendency for either height or weight among A-bomb survivors under the age of 11 when the estimated doses were 99 rad or less. In the group of 100 rad or more, however, both height and weight were found to be lower than the average among these age groups of A-bomb survivors. Similar findings were observed among girls in Nagasaki's survivors. According to the distance from the hypocenter, height was definitely shorter at the age of both 10 and 17 years among in uterus exposed A-bomb survivors in the group of 100 rad or more than the group of less than 100 rad; this was common in both Hiroshima and Nagasaki. Similarly, head circumstance was also smaller at the age of both 10 and 17 years in such A-bomb survivors. There was no evidence of correlation between physical growth and A-bomb radiation in F 1 offspring of A-bomb survivors. (N.K.)

  7. Operational development of small plant growth systems

    Science.gov (United States)

    Scheld, H. W.; Magnuson, J. W.; Sauer, R. L.

    1986-01-01

    The results of a study undertaken on the first phase of an empricial effort in the development of small plant growth chambers for production of salad type vegetables on space shuttle or space station are discussed. The overall effort is visualized as providing the underpinning of practical experience in handling of plant systems in space which will provide major support for future efforts in planning, design, and construction of plant-based (phytomechanical) systems for support of human habitation in space. The assumptions underlying the effort hold that large scale phytomechanical habitability support systems for future space stations must evolve from the simple to the complex. The highly complex final systems will be developed from the accumulated experience and data gathered from repetitive tests and trials of fragments or subsystems of the whole in an operational mode. These developing system components will, meanwhile, serve a useful operational function in providing psychological support and diversion for the crews.

  8. Varieties of Male-Sexual-Identity Development in Clinical Practice:A Neuropsychoanalytic Model

    Directory of Open Access Journals (Sweden)

    Frans eStortelder

    2014-12-01

    Full Text Available Variations of sexual-identity development are present in all cultures, as well as in many animal species. Freud, founding father of psychoanalysis, believed that all men have an inherited, bisexual disposition, and that many varieties of love and desire are experienced as alternative pathways to intimacy.In the neuropsychoanalytic model, psychic development starts with the constitutional self. The constitutional self is comprised of the neurobiological factors which contribute to sexual-identity development. These neurobiological factors are focused on biphasic sexual organization in the prenatal phase, based on variations in genes, sex hormones, and brain circuits. This psychosocial construction of sexual identity is determined through contingent mirroring by the parents and peers of the constitutional self. The development of the self—or personal identity—is linked with the development of sexual identity, gender-role identity, and procreative identity. Incongruent mirroring of the constitutional self causes alienation in the development of the self. Such alienation can be treated within the psychoanalytic relationship.This article presents a contemporary, neuropsychoanalytic, developmental theory of male-sexual identity relating to varieties in male-sexual-identity development, with implications for psychoanalytic treatment, and is illustrated with three vugnettes from clinical practice.

  9. Content analysis of public opinion on sexual expression and dementia: Implications for nursing home policy development.

    Science.gov (United States)

    Syme, Maggie L; Yelland, Erin; Cornelison, Laci; Poey, Judith L; Krajicek, Ryan; Doll, Gayle

    2017-08-01

    We examined public opinion of sexual expression and dementia to inform nursing home policy and practice. A content analysis was conducted on public comments (N=1194) posted in response to a New York Times article about a highly publicized legal case involving a husband engaging in sexual acts with his wife who had dementia, living in a nursing home. Researchers utilized constant comparative analysis to code the comments; reliability analysis showed moderately strong agreement at the subcategory level. Data were also coded to indicate whether the commenter thought the couple should or should not have been allowed to be sexual. One primary theme was identified: conditions necessary for someone to be sexual. Six categories were identified within this theme, with the public commentary considering factors such as marital relationships, intimacy needs and several sexual consent-related issues as key conditions necessary to be sexual in a nursing home setting. Overall, the majority of commenters were in support of sexual expression for an individual with dementia in the described situation. This study revealed sexual expression among individuals with dementia is a contentious issue with strong public opinions about how this should be managed in a nursing home setting. These opinions should be considered as policy related to sexual expression in nursing homes is developed. © 2016 The Authors. Health Expectations Published by John Wiley & Sons Ltd.

  10. Effects of sexually dimorphic growth hormone secretory patterns on arachidonic acid metabolizing enzymes in rodent heart

    International Nuclear Information System (INIS)

    Zhang, Furong; Yu, Xuming; He, Chunyan; Ouyang, Xiufang; Wu, Jinhua; Li, Jie; Zhang, Junjie; Duan, Xuejiao; Wan, Yu; Yue, Jiang

    2015-01-01

    The arachidonic acid (AA) metabolizing enzymes are the potential therapeutic targets of cardiovascular diseases (CVDs). As sex differences have been shown in the risk and outcome of CVDs, we investigated the regulation of heart AA metabolizing enzymes (COXs, LOXs, and CYPs) by sex-dependent growth hormone (GH) secretory patterns. The pulsatile (masculine) GH secretion at a physiological concentration decreased CYP1A1 and CYP2J3 mRNA levels more efficiently in the H9c2 cells compared with the constant (feminine) GH secretion; however, CYP1B1 mRNA levels were higher following the pulsatile GH secretion. Sex differences in CYP1A1, CYP1B1, and CYP2J11 mRNA levels were observed in both the wild-type and GHR deficient mice. No sex differences in the mRNA levels of COXs, LOXs, or CYP2E1 were observed in the wild-type mice. The constant GH infusion induced heart CYP1A1 and CYP2J11, and decreased CYP1B1 in the male C57/B6 mice constantly infused with GH (0.4 μg/h, 7 days). The activity of rat Cyp2j3 promoter was inhibited by the STAT5B protein, but was activated by C/EBPα (CEBPA). Compared with the constant GH administration, the levels of the nuclear phosphorylated STAT5B protein and its binding to the rat Cyp2j3 promoter were higher following the pulsatile GH administration. The constant GH infusion decreased the binding of the nuclear phosphorylated STAT5B protein to the mouse Cyp2j11 promoter. The data suggest the sexually dimorphic transcription of heart AA metabolizing enzymes, which might alter the risk and outcome of CVDs. GHR-STAT5B signal transduction pathway may be involved in the sex difference in heart CYP2J levels. - Highlights: • The transcription of heart Cyp1a1, Cyp1b1 and Cyp2j genes is sexually dimorphic. • There are no sex differences in the mRNA levels of heart COXs, LOXs, or CYP2E1. • GHR-STAT5B pathway is involved in sexually dimorphic transcription of heart Cpy2j genes. • Heart CYPs-mediated metabolism pathway of arachidonic acid may be sex

  11. Is it bullying or sexual harassment? Knowledge, attitudes, and professional development experiences of middle school staff.

    Science.gov (United States)

    Charmaraman, Linda; Jones, Ashleigh E; Stein, Nan; Espelage, Dorothy L

    2013-06-01

    This study fills a gap in the literature by examining how school staff members view bullying and sexual harassment and their role in preventing both. Given recent legislation, increasingly more attention is paid to bully prevention; however, student-on-student sexual harassment is less addressed. Four focus groups were conducted with 32 staff members from 4 midwestern public middle schools. Questions assessed professional development opportunities on bullying and sexual harassment prevention/intervention, personal definitions of these behaviors, and their perceptions of school norms regarding such behavior. Staff members recalled receiving more professional development on bullying than sexual harassment. They tended to define sexual harassment as something that occurs between adults and/or adults and students and did perceive their role in enforcing a "sexual harassment-free" peer-to-peer school zone. When school administrators fail to provide professional development on both bullying and sexual harassment, staff members do not understand that sexual harassment occurs between students. Thus, they are unaware of policies to protect students from harmful experiences in educational settings and are not likely to understand their own role in preventing them. © 2013, American School Health Association.

  12. Relative growth, ontogeny, and sexual dimorphism in gorilla (Gorilla gorilla gorilla and G. g. beringei): evolutionary and ecological considerations.

    Science.gov (United States)

    Taylor, A B

    1997-01-01

    Gorillas are the largest and among the most sexually dimorphic of all extant primates. While gorillas have been incorporated in broad-level comparisons among large-bodied hominoids or in studies of the African apes, comparisons between gorilla subspecies have been rare. During the past decade, however, behavioral, morphological, and molecular data from a number of studies have indicated that the western lowland (Gorilla gorilla gorilla) and eastern mountain (Gorilla gorilla beringei) subspecies differ to a greater extent than has been previously believed. In this study I compare patterns of relative growth of the postcranial skeleton to evaluate whether differences between subspecies result from the differential extension of common patterns of relative growth. In addition, patterns of ontogeny and sexual dimorphism are also examined. Linear skeletal dimensions and skeletal weight were obtained for ontogenetic series of male and female G.g. gorilla (n = 315) and G.g. beringei (n = 38). Bivariate and multivariate methods of analysis were used to test for differences in patterns of relative growth, ontogeny, and sexual dimorphism between sexes of each subspecies and in same-sex comparisons between subspecies. Results indicate males and females of both subspecies are ontogenetically scaled for postcranial proportions and that females undergo an earlier skeletal growth spurt compared to males. However, results also indicate that the onset of the female growth spurt occurs at different dental stages in lowland and mountain gorillas and that mountain gorillas may be characterized by higher rates of growth. Finally, data demonstrate lowland and mountain gorilla females do not differ significantly in adult body size, but mountain gorilla males are significantly larger than lowland gorilla males, suggesting mountain gorillas are characterized by a higher degree of sexual dimorphism in body size. Thus, although lowland and mountain gorillas do not appear to have evolved novel

  13. The Subjective Sexual Arousal Scale for Men (SSASM): preliminary development and psychometric validation of a multidimensional measure of subjective male sexual arousal.

    Science.gov (United States)

    Althof, Stanley E; Perelman, Michael A; Rosen, Raymond C

    2011-08-01

    Sexual arousal is a multifaceted process that involves both mental and physical components. No instrument has been developed and validated to assess subjective aspects of male sexual arousal. To develop and psychometrically validate a self-administered scale for assessing subjective male sexual arousal. Using recommendations of the Food and Drug Administration (FDA) guidance on patient-reported outcome instruments, important aspects of male sexual arousal were identified via qualitative research (focus groups and interviews) of U.S. men with erectile dysfunction (ED) and healthy controls. After a preliminary questionnaire was developed by a panel of experts, a quantitative study of men with ED and controls was conducted to psychometrically validate the Subjective Sexual Arousal Scale for Men (SSASM). To develop a male sexual arousal scale and determine its factor structure, reliability, and construct validity. Five aspects of male sexual arousal were identified from the qualitative focus groups and cognitive interviews. Men's preferred language for describing sexual arousal and preferred response formats were incorporated into the questions. Factor analysis of data from the quantitative study of 304 men aged 21 to 70 years identified five domains with eigenvalues >1: sexual performance (six items), mental satisfaction (five items), sexual assertiveness (three items), partner communication (three items), and partner relationship (three items). The five domains had a high degree of internal consistency (Cronbach's alpha values 0.88-0.94). Test-retest reliability over a 2- to 4-week period was high-moderately high (r values 0.75-0.88) for the five domain scores. Correlations between SSASM domain scores and standardized scale scores for social desirability, general health, life satisfaction, and sexual function demonstrated the construct validity of the scale. Preliminary validation data suggest that the 20-item SSASM scale may be useful as a multidimensional, reliable

  14. Inclusive growth versus pro-poor growth: Implications for tourism development

    NARCIS (Netherlands)

    Bakker, Martine; Messerli, H.R.

    2017-01-01

    Inclusive growth and pro-poor growth are terms embraced but not fully understood in the tourism community. This paper discusses the main concepts of inclusive growth and their implication for tourism development across the developing world. Is inclusive growth simply another term for pro-poor in

  15. Epilepsia y desarrollo sexual en adolescentes = Epilepsy and sexual development in adolescents

    Directory of Open Access Journals (Sweden)

    Carrizosa Moog, Jaime

    2011-03-01

    Full Text Available Los efectos de las epilepsias y de los fármacos antiepilépticos en el desarrollo sexual de los adolescentes han sido poco estudiados. Las epilepsias per se pueden alterar los ritmos de secreción de las hormonas del eje hipotálamo-hipofisiario y contribuir a que se altere la evolución puberal. Los fármacos antiepilépticos pueden afectar la talla en ambos sexos y producir cambios en el tamaño testicular y en la longitud del pene. En las mujeres adolescentes existen los riesgos del síndrome de ovario poliquístico y de la epilepsia catamenial. En los hombres se pueden afectar la fertilidad y el desempeño sexual. Es necesario hacer más estudios sobre este asunto, que incluyan los efectos de los nuevos medicamentos anticonvulsivantes.

  16. Reduced Treatment-Emergent Sexual Dysfunction as a Potential Target in the Development of New Antidepressants

    Directory of Open Access Journals (Sweden)

    David S. Baldwin

    2013-01-01

    Full Text Available Pleasurable sexual activity is an essential component of many human relationships, providing a sense of physical, psychological, and social well-being. Epidemiological and clinical studies show that depressive symptoms and depressive illness are associated with impairments in sexual function and satisfaction, both in untreated and treated patients. The findings of randomized placebo-controlled trials demonstrate that most of the currently available antidepressant drugs are associated with the development or worsening of sexual dysfunction, in a substantial proportion of patients. Sexual difficulties during antidepressant treatment often resolve as depression lifts but can endure over long periods and may reduce self-esteem and affect mood and relationships adversely. Sexual dysfunction during antidepressant treatment is typically associated with many possible causes, but the risk and type of dysfunction vary with differing compounds and should be considered when making decisions about the relative merits and drawbacks of differing antidepressants. A range of interventions can be considered when managing patients with sexual dysfunction associated with antidepressants, including the prescription of phosphodiesterase-5 inhibitors, but none of these approaches can be considered “ideal.” As treatment-emergent sexual dysfunction is less frequent with certain drugs, presumably related to differences in their pharmacological properties, and because current management approaches are less than ideal, a reduced burden of treatment-emergent sexual dysfunction represents a tolerability target in the development of novel antidepressants.

  17. Development of a structure-validated Sexual Dream Experience Questionnaire (SDEQ) in Chinese university students.

    Science.gov (United States)

    Chen, Wanzhen; Qin, Ke; Su, Weiwei; Zhao, Jialian; Zhu, Zhouyu; Fang, Xiangming; Wang, Wei

    2015-01-01

    Sexual dreams reflect the waking-day life, social problems and ethical concerns. The related experience includes different people and settings, and brings various feelings, but there is no systematic measure available to date. We have developed a statement-matrix measuring the sexual dream experience and trialed it in a sample of 390 young Chinese university students who had a life-long sexual dream. After both exploratory and confirmatory factor analyses, we have established a satisfactory model of four-factor (32 items). Together with an item measuring the sexual dream frequency, we developed a Sexual Dream Experience Questionnaire (SDEQ) based on the 32 items, and subsequently named four factors (scales) as joyfulness, aversion, familiarity and bizarreness. No gender differences were found on the four scale scores, and no correlations were found between the four scales and the sexual dream frequency or the sexual experience in real life. The SDEQ might help to characterize the sexual dreams in the healthy people and psychiatric patients. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. REGIONAL DEVELOPMENT THROUGH GROWTH AND URBAN DEVELOPMENT POLES IN ROMANIA

    Directory of Open Access Journals (Sweden)

    Stefana VARVARI

    2015-09-01

    Full Text Available In 2008 the Ministry of Development, Public Works and Housing (now the Ministry of Regional Development and Public Administration prepared the growth poles policy for Romania, establishing seven growth poles to be financed through the Regional Operational Programme 2007-1013, under the Priority Axis no. 1. For 2007-2013 there were also established 11 urban development poles. At present the Ministry is discussing with the European Commission the new Regional Operational Programme 2014-2020 in which the main policy lines regarding integrated territorial development also take into consideration the improvement of the quality of life and the “appearance” of towns and strengthening their role in the region. The main urban agglomerations (county seats are seen as development engines of the regions. The authors analyze the results obtained and the problems that appeared at regional level in what concerns the projects financed under Axis 1 of the ROP 2007-2013 by answering two main questions: did they really had the estimated impact on the growth and urban development poles and on the regions? and was there really an integrated approach used? Based on the results obtained from the analysis of the previous programming period the authors try to recommend some improvements that could be taken into consideration for the development of the Integrated urban development plans and priority projects that are going to be financed by ESI funds under Axis 4 of the new ROP 2014-2020, recommendations that could be taken into consideration when preparing the Guidelines for applicants for this axis.

  19. Sex, drugs and sports: prostaglandins, epitestosterone and sexual development.

    Science.gov (United States)

    Sanders, Bryan K

    2007-01-01

    Amateau and McCarthy's findings published in Nature Neuroscience (June 2004) are noteworthy for suggesting a role for prostaglandins in sexual development. However, evidence suggests that in manipulating PGE2, they unknowingly implicated 3alpha-hydroxysteroid dehydrogenase [E.C. 1.1.1.50], 3(or 17)alpha-hydroxysteroid dehydrogenase [E.C. 1.1.1.209] and their respective products, androsterone (ADT) and epitestosterone (EpiT), in the developmental masculinization of sex behavior. EpiT is generally regarded as a hormonally inactive 17alpha-epimer of testosterone (T). In rats, the kidney is the primary site of EpiT formation, whereas in humans it originates from the gonads, with only a small contribution secreted by the adrenals. Because the ratio of T to EpiT is nearly constant, it is presently used for assessing steroid abuse in competitive sports, where the World Anti-Doping Agency (WADA) considers a T/EpiT ratio >4 evidence of T doping. Despite its central role in the detection of illict anabolic steroid use, our knowledge of factors effecting EpiT production is poor. Clues in the literature, however, reveal that prostaglandin-mediated processes, such as LHRH release, may influence its production. Antimycotics, NSAIDs, and opioid analgesics used in sports medicine are all known to effect prostaglandin E2 synthesis. Primary PGs are potent inhibitors of ADT oxidation, while indomethacin, a prostaglandin blocker, powerfully inhibits 3alpha-HSD reduction and ADT oxidation. This is significant because ADT inhibits the oxidation of EpiT, and may modulate its antiandrogenic and neuroprotective effects. It is hypothesized that the T/EpiT ratio is increased by COX-2 inhibitors and opiod analgesics, and decreased by antimycotics that do not impair testosterone biosynthesis. Given the devastating personal and career consequences that may result from false positive drug tests, substantive research on the effects of PGE2 manipulations on EpiT is warranted.

  20. Green economic growth premise for sustainable development

    Directory of Open Access Journals (Sweden)

    Carmen Lenuţa TRICĂ

    2013-01-01

    Full Text Available Accelerating the global issues such as natural resource depletion, damage to the natural environment, economic and financial crises and consumption growth led to the shift of the development paradigm from consumption to sustainable development and recognition of the new path, namely green economy.At the European level a number of international organizations discussed issues of transition to green economy (EC, UNEP, OECD. In 2008, UNEP launched “Green Economy Initiative to Get the Global Markets Back to Work”, aiming to mobilize and re-focuse the global economy towards.This is the twin challenge of moving towards a green economy: radically reducing the footprint of developed countries, while simultaneously raising levels of social and material well being in developing countries.Without public intervention, the related market failures (i.e. market prices that do not fully reflect the environmental degradation generated by economic activity may delay or even prevent the development of environmentally-friendly technologies.Furthermore, in sectors such as electricity, network effects arising from existing infrastructures create additional barriers to the adoption of alternative sources of power, further hampering incentives to invest in new technologies.Given that the transition to a green economy requires increasing of investment in economic sectors that contribute to enhancing of natural capital and reduce environmental risks, we intend to analyze the main measures taken by Romania to ensure transition to green economy.

  1. Fetal programming of sexual development and reproductive function.

    Science.gov (United States)

    Zambrano, Elena; Guzmán, Carolina; Rodríguez-González, Guadalupe L; Durand-Carbajal, Marta; Nathanielsz, Peter W

    2014-01-25

    The recent growth of interest in developmental programming of physiological systems has generally focused on the cardiovascular system (especially hypertension) and predisposition to metabolic dysfunction (mainly obesity and diabetes). However, it is now clear that the full range of altered offspring phenotypes includes impaired reproductive function. In rats, sheep and nonhuman primates, reproductive capacity is altered by challenges experienced during critical periods of development. This review will examine available experimental evidence across commonly studied experimental species for developmental programming of female and male reproductive function throughout an individual's life-course. It is necessary to consider events that occur during fetal development, early neonatal life and prior to and during puberty, during active reproductive life and aging as reproductive performance declines. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  2. Consenting to sexual activity: the development and psychometric assessment of dual measures of consent.

    Science.gov (United States)

    Jozkowski, Kristen N; Sanders, Stephanie; Peterson, Zoë D; Dennis, Barbara; Reece, Michael

    2014-04-01

    Sexual assault prevention efforts have focused on educating students to obtain consent as a mechanism to reduce sexual assault, yet little is known about how college students consent to sex. Additionally, there are currently no measures available to assess students' consent to sex. The current study aimed to better understand college students consent by using a systematic approach to develop validated measures of sexual consent. This study integrated mixed methods via three phases and two waves of data collection to develop two measures of consent. In Phase 1, qualitative data were collected from college students (n = 185) to inform the design of quantitative measures aimed at assessing sexual consent at last sexual intercourse. In Phase 2, items were written for the closed-ended quantitative instrument and reviewed by a team of experts, educators, and clinicians. In Phase 3, a quantitative survey was administered to college students (n = 660) which included the measures of consent developed from the Phase 1 data; the measures were assessed for their psychometric properties. Exploratory factor analyses were utilized to assess the measures and resulted in five factors each for both consent scales. Both scales had high internal consistency reliability, showed gender differences, and showed differences across relationship status (single vs. in a relationship). The two newly developed measures assess unique constructs of consent and demonstrate assessments of specific concepts. Our findings provide an important contribution to the field of sexuality as these measures can be used in future research to better understand sexual consent.

  3. Anticipation of the sexual and gender development of children adopted by same-sex couples.

    Science.gov (United States)

    Gato, Jorge; Fontaine, Anne Marie

    2013-01-01

    The present study aimed to characterize beliefs surrounding the sexual and gender development of children adopted by lesbian and gay couples. Participants were 768 Portuguese university students. Using a quasiexperimental design, participants were presented with identical descriptions of a couple interested in adopting a child, manipulating couple sexual orientation and child gender. Participants were then asked to anticipate three aspects of the sexual and gender development of the adopted child: sexual orientation, gender role behavior, and gender identity. MANOVAs and follow-up ANOVAs were conducted in order to analyze the data. Results indicated that participants, particularly males, considered children adopted by either lesbian or gay couples to have a lower probability of developing a normative sexual and gender identity than children adopted by heterosexual couples. Both men and women considered that children would emulate the sexual orientation of their same-sex parents, and that a boy's gender role behavior was more at risk if he was adopted by a lesbian couple. Moreover, men were apprehensive about the gender role behavior of a boy adopted by a gay male couple. Overall, these results indicate persistence of biased evaluations of the sexual and gender development of children adopted by lesbian and gay parents. Furthermore, both gender of the participant and gender of the child play an important role in these evaluations. Results are discussed and interpreted as a way of "doing gender" in the context of hegemonic masculinity.

  4. The Conditions under which Growth-Fostering Relationships Promote Resilience and Alleviate Psychological Distress among Sexual Minorities: Applications of Relational Cultural Theory.

    Science.gov (United States)

    Mereish, Ethan H; Poteat, V Paul

    2015-09-01

    Relational cultural theory posits that resilience and psychological growth are rooted in relational connections and are facilitated through growth-fostering relationships. Framed within this theory, the current study examined the associations between growth-fostering relationships (i.e., relationships characterized by authenticity and mutuality) with a close friend and psychological distress among sexual minorities. More specifically, we tested the moderating effects of individuals' internalized homophobia and their friend's sexual orientation on the associations between growth-fostering relationship with their close friend and level of psychological distress. A sample of sexual minorities ( N = 661) were recruited online and completed a questionnaire. The 3-way interaction between (a) growth-fostering relationship with a close friend, (b) the close friend's sexual orientation, and (c) internalized homophobia was significant in predicting psychological distress. Among participants with low levels of internalized homophobia, a stronger growth-fostering relationship with a close heterosexual or LGBT friend was associated with less psychological distress. Among participants with high levels of internalized homophobia, a stronger growth-fostering relationship with a close LGBT friend was associated with less psychological distress but not with a heterosexual friend. Our results demonstrate that growth-fostering relationships may be associated with less psychological distress but under specific conditions. These findings illuminate a potential mechanism for sexual minorities' resilience and provide support for relational cultural theory. Understanding resilience factors among sexual minorities is critical for culturally sensitive and affirmative clinical practice and future research.

  5. The Conditions under which Growth-Fostering Relationships Promote Resilience and Alleviate Psychological Distress among Sexual Minorities: Applications of Relational Cultural Theory

    Science.gov (United States)

    Mereish, Ethan H.; Poteat, V. Paul

    2015-01-01

    Relational cultural theory posits that resilience and psychological growth are rooted in relational connections and are facilitated through growth-fostering relationships. Framed within this theory, the current study examined the associations between growth-fostering relationships (i.e., relationships characterized by authenticity and mutuality) with a close friend and psychological distress among sexual minorities. More specifically, we tested the moderating effects of individuals’ internalized homophobia and their friend’s sexual orientation on the associations between growth-fostering relationship with their close friend and level of psychological distress. A sample of sexual minorities (N = 661) were recruited online and completed a questionnaire. The 3-way interaction between (a) growth-fostering relationship with a close friend, (b) the close friend’s sexual orientation, and (c) internalized homophobia was significant in predicting psychological distress. Among participants with low levels of internalized homophobia, a stronger growth-fostering relationship with a close heterosexual or LGBT friend was associated with less psychological distress. Among participants with high levels of internalized homophobia, a stronger growth-fostering relationship with a close LGBT friend was associated with less psychological distress but not with a heterosexual friend. Our results demonstrate that growth-fostering relationships may be associated with less psychological distress but under specific conditions. These findings illuminate a potential mechanism for sexual minorities’ resilience and provide support for relational cultural theory. Understanding resilience factors among sexual minorities is critical for culturally sensitive and affirmative clinical practice and future research. PMID:26380836

  6. Measuring cervical cancer risk: development and validation of the CARE Risky Sexual Behavior Index.

    Science.gov (United States)

    Reiter, Paul L; Katz, Mira L; Ferketich, Amy K; Ruffin, Mack T; Paskett, Electra D

    2009-12-01

    To develop and validate a risky sexual behavior index specific to cervical cancer research. Sexual behavior data on 428 women from the Community Awareness Resources and Education (CARE) study were utilized. A weighting scheme for eight risky sexual behaviors was generated and validated in creating the CARE Risky Sexual Behavior Index. Cutpoints were then identified to classify women as having a low, medium, or high level of risky sexual behavior. Index scores ranged from 0 to 35, with women considered to have a low level of risky sexual behavior if their score was less than six (31.3% of sample), a medium level if their score was 6–10 (30.6%), or a high level if their score was 11 or greater (38.1%). A strong association was observed between the created categories and having a previous abnormal Pap smear test (p Sexual Behavior Index provides a tool for measuring risky sexual behavior level for cervical cancer research. Future studies are needed to validate this index in varied populations and test its use in the clinical setting.

  7. Sexuality

    OpenAIRE

    Williamson, I. R.

    2001-01-01

    This is a chapter in an edited book which dealt with inequalities in the British education system. Because of several policy developments relating to both lesbian and gay rights and educational provision, the chapter has become a little dated. However, at the time the book was well-received and was included on the reading lists of a number of teacher training programmes in the UK. The book received a very favourable review in the Australian publication Journal of Educational Enquiry (Raduntz...

  8. Development of romantic relationships and sexual activity in young adults with cerebral palsy: a longitudinal study.

    Science.gov (United States)

    Wiegerink, Diana J; Stam, Henk J; Gorter, Jan Willem; Cohen-Kettenis, Peggy T; Roebroeck, Marij E

    2010-09-01

    To describe the development of romantic relationships and sexual activity of young adults with cerebral palsy (CP), to investigate whether this development is associated with demographic and physical characteristics, and to compare the sexual activity of this group with an age-appropriate Dutch reference population. Prospective longitudinal study with 3 biannual assessments. Eight rehabilitation centers and departments in the southwestern regions of The Netherlands. Young adults (N=103; 61 men, 42 women) with CP without cognitive disabilities (age range at first assessment, 16-20 y; 82% Gross Motor Function Classification System level I or II). Not applicable. Sexual interest, romantic relationships, and sexual activity. We observed a significant increase in dating in young adults with CP during the 4-year period; however, the experience in romantic relationships did not increase largely during this period. Young adults with a lower education level began dating later than those with higher levels. Significantly more women were in current romantic relationships than men. During the 4 years, participants' sexual experience increased significantly for all sexual milestones evaluated. Level of gross motor function was associated significantly with intercourse experience. Compared with an age-appropriate Dutch reference population, young adults with CP participated at a lower level in romantic relationships and sexual activities, but had equal sexual interest at the final assessment. Young ambulatory adults with CP had similar sexual interests and had increasing experiences with romantic relationships and sexual activities during the transition from late adolescence to young adulthood. However, the percentage of young adults with CP in current romantic relationships was low, especially for men.

  9. Hormone symphony during root growth and development.

    Science.gov (United States)

    Garay-Arroyo, Adriana; De La Paz Sánchez, María; García-Ponce, Berenice; Azpeitia, Eugenio; Alvarez-Buylla, Elena R

    2012-12-01

    Hormones regulate plant growth and development in response to external environmental stimuli via complex signal transduction pathways, which in turn form complex networks of interaction. Several classes of hormones have been reported, and their activity depends on their biosynthesis, transport, conjugation, accumulation in the vacuole, and degradation. However, the activity of a given hormone is also dependent on its interaction with other hormones. Indeed, there is a complex crosstalk between hormones that regulates their biosynthesis, transport, and/or signaling functionality, although some hormones have overlapping or opposite functions. The plant root is a particularly useful system in which to study the complex role of plant hormones in the plastic control of plant development. Physiological, cellular, and molecular genetic approaches have been used to study the role of plant hormones in root meristem homeostasis. In this review, we discuss recent findings on the synthesis, signaling, transport of hormones and role during root development and examine the role of hormone crosstalk in maintaining homeostasis in the apical root meristem. Copyright © 2012 Wiley Periodicals, Inc.

  10. Animal studies on growth and development.

    Science.gov (United States)

    Lerchl, Alexander

    2011-12-01

    Despite the fact that no plausible biological mechanism has yet been identified how electromagnetic fields below recommended exposure limits could negatively affect health of animals or humans, many experiments have been performed in various animal species, mainly mice and rats, to investigate the possible effects on growth and development. While older studies often suffered from sub-optimal exposure conditions, recent investigations, using sophisticated exposure devices and thus preventing thermal effects, have been performed without these limitations. In principle, two types of studies can be addressed: those which have investigated the carcinogenic or co-carcinogenic effects of exposure in developing animals, and those which have been done in developing animals without the focus on carcinogenic or co-carcinogenic effects. In both areas, the vast majority of publications did not show adverse effects. The largest study so far has been done in normal mice which have been chronically exposed to UMTS signals up to 1.3 W/kg SAR, thus 16 times higher than the whole-body exposure limit for humans. Even after four generations, no systematic or dose-dependent alterations in development or fertility could be found, supporting the view that negative effects on humans are very unlikely. Ongoing experiments in our laboratory investigate the effects of head-only exposure in rats (up to 10 W/kg local SAR) which are exposed from 14 days of age daily for 2 h. A battery of behavioral tests is performed in young, adult, and pre-senile animals. The results will help to clarify possible effects of exposure on brain development. Copyright © 2011 Elsevier Ltd. All rights reserved.

  11. Survival, growth and sexual maturation in Atlantic salmon exposed to infectious pancreatic necrosis

    DEFF Research Database (Denmark)

    Lillehammer, Marie; Ødegård, Jørgen; Madsen, Per

    2013-01-01

    Background Outbreaks of infectious pancreatic necrosis (IPN) in Atlantic salmon can result in reduced growth rates in a fraction of the surviving fish (runts). Genetic and environmental variation also affects growth rates within different categories of healthy animals and runts, which complicates...... may be useful for the genetic analysis of diseases detected mainly through indicator traits....... identification of runts. Mixture models are commonly used to identify the underlying structures in such data, and the aim of this study was to develop Bayesian mixture models for the genetic analysis of health status (runt/healthy) of surviving fish from an IPN outbreak. Methods Five statistical models were...

  12. The Role of Sexual Health Professionals in Developing a Shared Concept of Risky Sexual Behavior as it Relates to HIV Transmission.

    Science.gov (United States)

    Brawner, Bridgette M; Alexander, Kamila A; Fannin, Ehriel F; Baker, Jillian L; Davis, Zupenda M

    2016-01-01

    "Risky sexual behavior" accounts for the majority of new HIV infections regardless of gender, age, geographic location, or ethnicity. The phrase, however, refers to a relatively nebulous concept that hampers development of effective sexual health communication strategies. The purpose of this paper was to propose development of a shared conceptual understanding of "risky sexual behavior." We reviewed multidisciplinary HIV/AIDS literature to identify definitions of risky sexual behavior. Both the linguistic components and the social mechanisms that contribute to the concept of risky sexual behaviors were noted. Risky sexual behavior was often defined in a subjective manner in the literature, even in the scientific research. We urge a paradigm shift to focus on explicit behaviors and the social context of those behaviors in determining HIV risk. We also propose a new definition that reduces individual biases and promotes a broader discussion of the degree of sexual risk across a diversity of behavioral contexts. Sexual health professionals can strengthen practice and research initiatives by operating from a concise working definition of risky sexual behavior that is broadly transferable and expands beyond a traditional focus on identity-based groups. © 2015 Wiley Periodicals, Inc.

  13. Taking ICPD beyond 2015: negotiating sexual and reproductive rights in the next development agenda.

    Science.gov (United States)

    Girard, Françoise

    2014-01-01

    On the twentieth anniversary of the International Conference on Population and Development (ICPD), activists, governments and diplomats engaged in the fight for sexual and reproductive health and rights (SRHR) are anxious to ensure that these issues are fully reflected in the development agenda to succeed the Millennium Development Goals after 2015. In inter-governmental negotiations since 1994 and particularly in the period 2012-2014, governments have shown that they have significantly expanded their understanding of a number of so-called 'controversial' issues in the ICPD agenda, whether safe abortion, adolescent sexual and reproductive health services, comprehensive sexuality education or sexual rights. As in the past and in spite of an increasingly complex and difficult multilateral environment, countering the highly organised conservative opposition to SRHR has required a well-planned and determined mobilisation by progressive forces from North and South.

  14. Does globalization contribute to economic growth in developing ...

    African Journals Online (AJOL)

    This paper examines empirically whether or not globalization contributes to economic growth in developing countries, drawing empirical lessons from Nigeria. The globalization – growth link, is anchored on Husain Schematic representation, Solow model, and the new growth (endogenous growth) theory. The paper adopts ...

  15. What young people want from a sexual health website: design and development of Sexunzipped.

    Science.gov (United States)

    McCarthy, Ona; Carswell, Kenneth; Murray, Elizabeth; Free, Caroline; Stevenson, Fiona; Bailey, Julia V

    2012-10-12

    Sexual health education in the United Kingdom is of variable quality, typically focusing on the biological aspects of sex rather than on communication, relationships, and sexual pleasure. The Internet offers a unique opportunity to provide sexual health education to young people, since they can be difficult to engage but frequently use the Internet as a health information resource. To explore through qualitative research young people's views on what elements of a sexual health website would be appealing and engaging, and their views on the content, design, and interactive features of the Sexunzipped intervention website. We recruited 67 young people aged 16-22 years in London, UK. We held 21 focus groups and 6 one-to-one interviews to establish sexual health priorities, views on website look and feel, and what features of a sexual heath website would attract and engage them. Two researchers facilitated the focus groups, using a semistructured topic guide to lead the discussions and asking open questions to elicit a range of views. The discussions and interviews were audio recorded and detailed notes were made on key topics from the audio recording. Young people's views influenced design templates for the content and interactive features of Sexunzipped. Young people particularly wanted straightforward information on sexual pleasure, sexually transmitted infections and pregnancy, how to communicate with partners, how to develop skills in giving pleasure, and emotions involved in sex and relationships. Focus group participants wanted social interaction with other young people online and wanted to see themselves reflected in some way such as through images or videos. While it is challenging to meet all of young people's technological and design requirements, consultation with the target audience is valuable and necessary in developing an online sexual health intervention. Young people are willing to talk about sensitive issues, enjoy the discussions, and can offer key

  16. Retrospective Recall of Sexual Orientation Identity Development Among Gay, Lesbian, and Bisexual Adults

    Science.gov (United States)

    Calzo, Jerel P.; Antonucci, Toni C.; Mays, Vickie M.; Cochran, Susan D.

    2011-01-01

    Although recent attention has focused on the likelihood that contemporary sexual minority youth (i.e., gay, lesbian, bisexual [GLB]) are “coming out” at younger ages, few studies have examined if early sexual orientation identity development is also present in older GLB cohorts. We analyze retrospective data on the timing of sexual orientation milestones in a sample of sexual minorities drawn from the California Quality of Life Surveys. Latent profile analysis of 1,260 GLB adults, ages 18-84 years identified three trajectories of development: Early (n = 951, milestones spanning ages 12 to 20), Middle (n = 239, milestones spanning ages 18 to 31), and Late (n = 70, milestones spanning ages 32 to 43). Motivated by previous research on variability in adolescent developmental trajectories, post-hoc analyses of the Early Profile group identified two sub-groups: Child-Onset (n = 284, milestones spanning ages 8 to 18), and Teen-Onset (n = 667, milestones spanning ages 14 to 22). Nearly all patterns of development were identity-centered, with average age of self-identification as GLB preceding average age of first same-sex sexual activity. Overall, younger participants and the majority of older participants were classified to the Early Profile, suggesting that early development is common regardless of age cohort. The additional gender differences observed in the onset and pace of sexual orientation identity development warrant future research. PMID:21942662

  17. Both cell-autonomous mechanisms and hormones contribute to sexual development in vertebrates and insects.

    Science.gov (United States)

    Bear, Ashley; Monteiro, Antónia

    2013-08-01

    The differentiation of male and female characteristics in vertebrates and insects has long been thought to proceed via different mechanisms. Traditionally, vertebrate sexual development was thought to occur in two phases: a primary and a secondary phase, the primary phase involving the differentiation of the gonads, and the secondary phase involving the differentiation of other sexual traits via the influence of sex hormones secreted by the gonads. In contrast, insect sexual development was thought to depend exclusively on cell-autonomous expression of sex-specific genes. Recently, however, new evidence indicates that both vertebrates and insects rely on sex hormones as well as cell-autonomous mechanisms to develop sexual traits. Collectively, these new data challenge the traditional vertebrate definitions of primary and secondary sexual development, call for a redefinition of these terms, and indicate the need for research aimed at explaining the relative dependence on cell-autonomous versus hormonally guided sexual development in animals. © 2013 The Authors. BioEssays published by WILEY Periodicals, Inc.

  18. The Development of a Sexual Abuse Severity Score: Characteristics of Childhood Sexual Abuse Associated with Trauma Symptomatology, Somatization, and Alcohol Abuse

    Science.gov (United States)

    Zink, Therese; Klesges, Lisa; Stevens, Susanna; Decker, Paul

    2009-01-01

    Childhood sexual abuse (CSA) is common and is associated with both mental and physical health problems in adulthood. Using data from an age- and sex-stratified population survey of 600 Olmsted County, Minnesota, residents, a Sexual Abuse Severity Score was developed. The abuse characteristics of 156 CSA respondents were associated with…

  19. Coming Out and the Potential for Growth in Sexual Minorities: The Role of Social Reactions and Internalized Homonegativity.

    Science.gov (United States)

    Solomon, David; McAbee, James; Åsberg, Kia; McGee, Ashley

    2015-01-01

    Coming out is a significant and sometimes difficult process in the lives of sexual minorities, but disclosure can also affect wellbeing in positive ways, including reduced distress and greater relationship satisfaction. This study investigates the possibility of stress-related growth and depreciation following coming out. To obtain a diverse sample with varying coming-out experiences, data were collected from undergraduate students as well as from online sources, including lesbian, gay, and bisexual support groups and Pride groups. Regression analyses indicated that negative social reactions to coming out predicted both growth and depreciation, although they more strongly predicted depreciation. Positive social reactions were positively related to stress-related growth, while internalized homonegativity was inversely associated with growth. Although the two sample sources (online and campus) differed in some ways, sample source was not a significant predictor in the regressions, nor was it indicated as a moderator in exploratory ANOVA analyses.

  20. Hox in hair growth and development

    Science.gov (United States)

    Awgulewitsch, Alexander

    2003-05-01

    The evolutionarily conserved Hox gene family of transcriptional regulators has originally been known for specifying positional identities along the longitudinal body axis of bilateral metazoans, including mouse and man. It is believed that subsequent to this archaic role, subsets of Hox genes have been co-opted for patterning functions in phylogenetically more recent structures, such as limbs and epithelial appendages. Among these, the hair follicle is of particular interest, as it is the only organ undergoing cyclical phases of regression and regeneration during the entire life span of an organism. Furthermore, the hair follicle is increasingly capturing the attention of developmental geneticists, as this abundantly available miniature organ mimics key aspects of embryonic patterning and, in addition, presents a model for studying organ renewal. The first Hox gene shown to play a universal role in hair follicle development is Hoxc13, as both Hoxc13-deficient and overexpressing mice exhibit severe hair growth and patterning defects. Differential gene expression analyses in the skin of these mutants, as well as in vitro DNA binding studies performed with potential targets for HOXC13 transcriptional regulation in human hair, identified genes encoding hair-specific keratins and keratin-associated proteins (KAPs) as major groups of presumptive Hoxc13 downstream effectors in the control of hair growth. The Hoxc13 mutant might thus serve as a paradigm for studying hair-specific roles of Hoxc13 and other members of this gene family, whose distinct spatio-temporally restricted expression patterns during hair development and cycling suggest discrete functions in follicular patterning and hair cycle control. The main conclusion from a discussion of these potential roles vis-à-vis current expression data in mouse and man, and from the perspective of the results obtained with the Hoxc13 transgenic models, is that members of the Hox family are likely to fulfill essential roles

  1. Recent sexual victimization and drinking behavior in newly matriculated college students: a latent growth analysis.

    Science.gov (United States)

    Griffin, Melissa J; Wardell, Jeffrey D; Read, Jennifer P

    2013-12-01

    College matriculation is a time of developmental and social change and is often a time of heavy drinking. Sexual victimization (SV) is prevalent in late adolescence and poses additional risk for problem drinking behavior. Thus, matriculating students with a SV history may be at heightened risk for maladaptive alcohol use while transitioning through the first year of college. Furthermore, victimization that has occurred close to college matriculation may confer particular risk for problem alcohol use, because the added stressor of coping with a SV while negotiating the transition into college may lead to risky drinking behavior. Therefore, examining the influence of SV timing (i.e., recency) on drinking patterns in freshman year was the aim of the present study. Matriculating undergraduates with a history of SV were assessed at six points during freshman year. Using latent growth curve modeling, we tested differences in trajectories of drinking behavior (i.e., alcohol use, binge drinking) between students who reported a recent SV and those who reported a more distal SV. Students endorsing a recent SV evidenced greater overall levels of alcohol use and higher levels of binge drinking than individuals with SV that was less recent. Moreover, the recent SV group showed significantly more variability in drinking outcomes over freshman year, with escalations mapping onto more salient periods of transition over the first college year. SV that occurs close to college entry is associated with specific and persistent risk for maladaptive drinking behavior in newly matriculated college students. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  2. Divorce and sexual risk among U.S. women: findings from the national survey of family growth.

    Science.gov (United States)

    Liddon, Nicole; Leichliter, Jami S; Habel, Melissa A; Aral, Sevgi O

    2010-11-01

    Most research focusing on marital status and sexual risk has compared married and single midadult women without differentiating single women by their ever married status. We elucidate differences in sexual risk among divorced and never married women. Data from the National Survey of Family Growth (NSFG) (n = 5,081) were analyzed to compare divorced and never married women in terms of recent and lifetime sex partners, condom use at last vaginal sex, and other sexual risk behaviors. Overall, 13.1% of the women were currently divorced or separated, 62.1% were currently married, 8.3% were cohabitating, and 16.4% were never married. Divorced/separated women were more likely to report 5 or more lifetime sex partners and 2 or more sex partners in the past year than never married women. They were less likely to report condom use. Current findings expose sexual behavioral discrepancies within the single category of women and the need to redefine risk groups for surveillance and intervention efforts.

  3. CAPITAL MARKET DEVELOPMENT AND ECONOMIC GROWTH: THE CASE OF ROMANIA

    Directory of Open Access Journals (Sweden)

    FLAVIA BARNA

    2010-01-01

    Full Text Available Capital markets play an important role in the economic development of emerging capital markets. Well functioning markets insure that both corporations and investors get or receive fair prices for their securities. In the literature on endogenous growth, the link between capital markets development and economic growth has received much attention. Thispaper examines the correlation between capital market development and economic growth in Romania using a regression function. The results show that the capital market development is positively correlated with economic growth, with feed-back effect, but the strongest link is from economic growth to capital market, suggesting that financial development follows economic growth, economic growth determining financial institutions to change and develop.

  4. Changing patterns of adolescent sexual behavior: consequences for health and development.

    Science.gov (United States)

    Friedman, H L

    1992-07-01

    Sexuality is a fundamental quality of human life, important for health, happiness, individual development, and indeed for the preservation of the human race. During the dynamic period of adolescence in which the passage from childhood to maturity takes place, sexuality takes on new dimensions; feelings become more intense, relationships become more complex, and the consequences of sexual behavior are radically altered. This not only affects the behavior of young people but also of those who interact with them, their families and peers, and those who work in the health, education, youth, social welfare, and other sectors. In the contemporary world the conditions of life for many young people have also changed, and with it patterns of sexual behavior. In general, earlier puberty, later marriage, a decline in the family leading to less control and more autonomy, and intense exposure to sexual stimuli via the mass media and travel across cultural boundaries have made pre-marital adolescent sexual activity more common. This has added to traditional problems of early marriage, newer problems of early pregnancy, childbirth, and induced abortion outside of marriage, sexually transmitted diseases, and human immunodeficiency syndrome infection leading to acquired immunodeficiency syndrome. But the work of the World Health Organization (WHO), along with many others in the field, strongly suggests that given appropriate information and services, trust and equity between the sexes, young people will behave responsibly and well. In this paper some of the findings from methods developed by WHO for research, training, advocacy, and evaluation, and findings in relation to patterns and determinants of sexual and reproductive health and development will be described, and future directions suggested.

  5. Development and validation of a five-factor sexual satisfaction and distress scale for women: the Sexual Satisfaction Scale for Women (SSS-W).

    Science.gov (United States)

    Meston, Cindy; Trapnell, Paul

    2005-01-01

    This article presents data based on the responses of over 800 women who contributed to the development of the Sexual Satisfaction Scale for Women (SSS-W). The aim of this study was to develop a comprehensive, multifaceted, valid, and reliable self-report measure of women's sexual satisfaction and distress. Phase I involved the initial selection of items based on past literature and on interviews of women diagnosed with sexual dysfunction and an exploratory factor analysis. Phase II involved an additional administration of the questionnaire, factor analyses, and refinement of the questionnaire items. Phase III involved administration of the final questionnaire to a sample of women with clinically diagnosed sexual dysfunction and controls. Psychometric evaluation of the SSS-W conducted in a sample of women meeting DSM-IV-TR criteria for female sexual dysfunction and in a control sample provided preliminary evidence of reliability and validity. The ability of the SSS-W to discriminate between sexually functional and dysfunctional women was demonstrated for each of the SSS-W domain scores and total score. The SSS-W is a brief, 30-item measure of sexual satisfaction and sexual distress, composed of five domains supported by factor analyses: contentment, communication, compatibility, relational concern, and personal concern. It exhibits sound psychometric properties and has a demonstrated ability to discriminate between clinical and nonclinical samples.

  6. Development of a Cued Pro- and Antisaccade Paradigm: An Indirect Measure to Explore Automatic Components of Sexual Interest.

    Science.gov (United States)

    Oberlader, Verena A; Ettinger, Ulrich; Banse, Rainer; Schmidt, Alexander F

    2017-11-01

    We developed a cued pro- and antisaccade paradigm (CPAP) to explore automatic components of sexual interest. Heterosexual participants (n = 32 women, n = 25 men) had to perform fast eye movements toward and away from sexually relevant or irrelevant stimuli across a congruent (i.e., prosaccade toward sexually relevant stimuli, antisaccade away from sexually irrelevant stimuli) and an incongruent condition (i.e., prosaccade toward sexually irrelevant stimuli, antisaccade away from sexually relevant stimuli). We hypothesized that pro- and antisaccade performance would be influenced by the sexual interest-specific relevance of the presented stimulus (i.e., nude female or male stimulus) and the instructed task (i.e., pro- or antisaccade) and, thus, differ meaningfully between conditions. Results for prosaccades toward sexually relevant stimuli in the congruent condition showed that error rates were lower and latencies were shorter compared with prosaccades toward sexually irrelevant stimuli in the incongruent condition, but only for male participants. In addition, error rates for antisaccades away from sexually irrelevant stimuli in the congruent condition were lower than for antisaccades away from sexually relevant stimuli in the incongruent condition, for both female and male participants. Latencies of antisaccades, however, did not differ between conditions. In comparison with established indirect sexual interest paradigms, the CPAP benefits from measuring highly automated processes less prone to deliberate control. To this end, the CPAP could be applied to explore the interplay of early automatic and deliberate components of sexual information processing.

  7. Sexual size dimorphism and growth plasticity in snakes: an experiment on the Western Diamond-backed Rattlesnake (Crotalus atrox).

    Science.gov (United States)

    Taylor, Emily N; Denardo, Dale F

    2005-07-01

    We conducted an experiment to examine the effects of sex and food intake on growth, mass gain, and attainment of sexual maturity in Western Diamond-backed Rattlesnakes (Crotalus atrox). We also measured testosterone levels to determine whether testosterone might be involved in the male-biased sexual size dimorphism observed in this species. We collected neonate rattlesnakes and raised them in the laboratory for 2 years on either a high-intake diet (fed one mouse per week) or a low-intake diet (fed one mouse every 3 weeks). High-intake snakes grew and gained mass more rapidly than low-intake snakes, but males did not grow or gain mass more rapidly than females in either treatment group. High-intake snakes attained reproductive maturity earlier than low-intake snakes, indicating that size, not age, is the critical determinant of reproductive maturity. Males had higher levels of testosterone than females but did not grow more quickly, suggesting that testosterone may not affect growth in this species and may therefore not be the proximate determinant of sexual size dimorphism.

  8. Development of a comprehensive survey of sexuality issues including a self-report version of the International Spinal Cord Injury sexual function basic data sets.

    Science.gov (United States)

    New, P W; Currie, K E

    2016-08-01

    Questionnaire development, validation and completion. Develop comprehensive survey of sexuality issues including validated self-report versions of the International Spinal Cord Injury male sexual function and female sexual and reproductive function basic data sets (SR-iSCI-sexual function). People with spinal cord damage (SCD) living in the community, Australia from August 2013 to June 2014. An iterative process involving rehabilitation medicine clinicians, a nurse specialising in sexuality issues in SCD and people with SCD who developed a comprehensive survey that included the SR-iSCI-sexual function. Participants recruitment through spinal rehabilitation review clinic and community organisations that support people with SCD. Surveys completed by 154 people. Most were male (n=101, 65.6%). Respondents' median age was 50 years (interquartile range (IQR) 38-58), and they were a median of 10 years (IQR 4-20) after the onset of SCD. Sexual problems unrelated to SCD were reported by 12 (8%) respondents, and 114 (n=75.5%) reported sexual problems because of SCD. Orgasms were much less likely (χ(2)=13.1, P=0.006) to be normal in males (n=5, 5%) compared with females (n=11, 22%). Males had significantly worse (χ(2)=26.0, P=0.001) psychogenic genital functioning (normal n=9, 9%) than females (normal n=13, 26%) and worse (χ(2)=10.8, P=0.013) reflex genital functioning. Normal ejaculation was reported in only three (3%) men. Most (n=26, 52%) women reported reduced or absent menstruation pattern since SCD. The SR-iSCI-sexual function provides a useful tool for researchers and clinicians to collect information regarding patient-reported sexual functioning after SCD and to facilitate comparative studies.

  9. The role of masturbation in healthy sexual development: perceptions of young adults.

    Science.gov (United States)

    Kaestle, Christine E; Allen, Katherine R

    2011-10-01

    Despite efforts to identify masturbation as a strategy to improve sexual health, promote relational intimacy, and reduce unwanted pregnancy, STIs, and HIV transmission, masturbation as a context for healthy sexual development has been met with silence or trepidation in the scientific and educational communities. Relegated to the realm of commercial media, rather than rational discourse in families, schools, and the general public, young people receive mixed messages about this non-reproductive sexual behavior. In order to explore how young adults have learned about masturbation and currently perceive masturbation, we conducted a grounded theory study of 72 college students (56 females; 16 males) enrolled in a human sexuality class. Findings revealed that a young adult's perceptions of and feelings toward masturbation were the result of a developmental process that included: (1) learning about the act of masturbation and how to do it, (2) learning and internalizing the social contradiction of stigma and taboo surrounding this pleasurable act, and (3) coming to terms with this tension between stigma and pleasure. Although nearly all participants learned about masturbation through the media and peers (not parents or teachers), gender was salient in coming to terms with the contradiction of stigma and pleasure. Most of the women reported either still struggling with the contradiction or accepting it as normal. Most of the men recognized the beneficial aspects for healthy sexual development that result from masturbation. Both male and female participants identified differential sexual scripts as contributing to the double standard.

  10. Financial development and economic growth. An empirical analysis for Ireland

    Directory of Open Access Journals (Sweden)

    Antonios Adamopoulos

    2010-07-01

    Full Text Available This study investigated the relationship between financial development and economicgrowth for Ireland for the period 1965-2007 using a vector error correction model (VECM.Questions were raised whether financial development causes economic growth or reverselytaking into account the positive effect of industrial production index. Financial marketdevelopment is estimated by the effect of credit market development and stock marketdevelopment on economic growth. The objective of this study was to examine the long-runrelationship between these variables applying the Johansen cointegration analysis takinginto account the maximum eigenvalues and trace statistics tests. Granger causality testsindicated that economic growth causes credit market development, while there is a bilateralcausal relationship between stock market development and economic growth. Therefore, itcan be inferred that economic growth has a positive effect on stock market development andcredit market development taking into account the positive effect of industrial productiongrowth on economic growth for Ireland.

  11. Testosterone and pubertal development as predictors of sexual activity: a panel analysis of adolescent males.

    Science.gov (United States)

    Halpern, C T; Udry, J R; Campbell, B; Suchindran, C

    1993-01-01

    Strong cross-sectional relationships between testosterone (T) and sexual activity have been found for human adolescent males, even when level of pubertal development is controlled; however, it has not been demonstrated that sexual behavior increases over time as a consequence of hormonal changes. The purpose of this paper was to extend previous cross-sectional findings by demonstrating that sexual behavior is initiated and increases within individuals over time as a direct function of changes in T levels, rather than indirectly through pubertal development. Analyses are based on a 3-year panel study of about 100 7th- and 8th-grade adolescent boys. Pubertal development and changes in pubertal development were significantly and positively related to changes in sexual ideation, noncoital behavior, and to the transition to sexual intercourse. Testosterone levels at study entry were significantly related to coital status at Time 1 and also predicted the transition to nonvirgin status. However, changes in hormone levels during the 3 years of study participation did not predict changes in ideation or noncoital sexual activity, regardless of the period of change or the lag time to effects. The panel data suggest, in contrast to earlier cross-sectional results, that change in pubertal development is related to the initiation of sexual activity because of its social stimulus value, and not solely because it is determined by, or is a proxy for, changing hormone levels. Possible causes of the different findings in the cross-sectional and panel data are examined, and the implications and meaning of hormone/behavior relationships based on single measures are discussed.

  12. The Developmental Association of Sexual Self-Concept with Sexual Behavior among Adolescent Women

    Science.gov (United States)

    Hensel, Devon J.; Fortenberry, J. Dennis; O'Sullivan, Lucia F.; Orr, Donald P.

    2011-01-01

    Developing a sexual self-concept is an important developmental task of adolescence; however, little empirical evidence describes this development, nor how these changes are related to development in sexual behavior. Using longitudinal cohort data from adolescent women, we invoked latent growth curve analysis to: (1) examine reciprocal development…

  13. Adolescents' Use of Sexually Explicit Internet Material and Their Sexual Attitudes and Behavior: Parallel Development and Directional Effects

    Science.gov (United States)

    Doornwaard, Suzan M.; Bickham, David S.; Rich, Michael; ter Bogt, Tom F. M.; van den Eijnden, Regina J. J. M.

    2015-01-01

    Although research has repeatedly demonstrated that adolescents' use of sexually explicit Internet material (SEIM) is related to their endorsement of permissive sexual attitudes and their experience with sexual behavior, it is not clear how linkages between these constructs unfold over time. This study combined 2 types of longitudinal modeling,…

  14. Role of Growth Factors in the Development of Mandible

    Directory of Open Access Journals (Sweden)

    Deepu Leander

    2011-01-01

    Growth factors are a large family of polypeptide molecules that regulate cell division in many tissues by autocrine or paracrine mechanisms. Depending on what receptors are activated, growth factors can initiate mitogenic, antiproliferative or trophic effects, that is growth factors act as positive or negative modulators of cell proliferation. The synergistic and orchestrated influences of various growth factors and other regulatory factors that are endogenously expressed in the condyle have been well documented. Growth factors do not only play an important role in embryonic development and adult tissue homeostasis but also in pathological situations, like infection and wound healing. Consequently, the applications of growth factors have therapeutic applications.

  15. Population Growth and Poverty in the Developing World.

    Science.gov (United States)

    Birdsall, Nancy

    1980-01-01

    The link between rapid population growth and the absolute poverty which currently afflicts 780 million people in developing countries (excluding China and other centrally planned economies) is examined. As a result of rapid population growth, many countries suffer slow per capita income growth, a lack of progress in reducing income inequality, and…

  16. Models of Economic Growth and Development in the Context of ...

    African Journals Online (AJOL)

    The Way Forward for Africa. Lansana Keita* ... to such progress. Key Words: economic growth, economic development, human capital, growth models. Résumé. La littérature économique depuis l'avènement de l'économie moderne a été ..... between the economy's growth rate according to investment and the propensity to ...

  17. The evolution of development of vascular cambia and secondary growth

    Science.gov (United States)

    Andrew Groover; Rachel Spicer

    2010-01-01

    Secondary growth from vascular cambia results in radial, woody growth of stems. The innovation of secondary vascular development during plant evolution allowed the production of novel plant forms ranging from massive forest trees to flexible, woody lianas. We present examples of the extensive phylogenetic variation in secondary vascular growth and discuss current...

  18. Growth and development and their environmental and biological determinants

    Directory of Open Access Journals (Sweden)

    Kelly da Rocha Neves

    2016-05-01

    Conclusion: The results showed a high prevalence of stunting and below‐average results for cognitive/language development among the participating children. Both environmental and biological factors were related to growth and development. However, biological variables showed a greater association with growth, whereas environmental variables were associated with development.

  19. BANKING SECTOR DEVELOPMENT AND ECONOMIC GROWTH INPALESTINE; 1995-2014

    Directory of Open Access Journals (Sweden)

    Gaber H. Abugamea

    2016-07-01

    Full Text Available This study uses both OLS regression estimation and Granger Causality test toinvestigate the relationship between the banking sector development andeconomic growth in Palestine over the period 1995-2014.OLS results show asignificant impact of banking size with a negative sign, insignificant impact ofcredit lending with a marginal one for lag credit andinsignificant impact ofefficiency on economic growth, respectively.Granger Causality testresultsshowone way causality runningfrom banking size to(GDPeconomic growthandfrom banking efficiency to(GDP per capitaeconomic growth one. Overall resultsreveals a weak nexus between banking sector development and economic growth.In specific, it recommends more improving in banking lending policy to beeffective in promoting economic growth.

  20. Infantile sexuality: Its place in the conceptual developments of Anna Freud and Donald W. Winnicott.

    Science.gov (United States)

    Joyce, Angela

    2016-06-01

    This essay explores the place of infantile sexuality in the theories of Anna Freud and Donald W Winnicott. Both Anna Freud and D.W. Winnicott incorporated and at the same time changed the classical psychoanalytic account of infantile sexuality and the instinctual drives. Whilst Anna Freud remained closer to her father's original conceptualization, she developed a multidimensional model of development which gave the drives a foundational status whist also maintaining their significance in giving meaning and texture to children's subjective experience. Winnicott also retained much of S. Freud's original theorizing except that in a fundamental way he turned it on its head when considering earliest development. For him the establishment of the self was paramount, and the drives and infantile sexuality merely served to give substance to that self. Copyright © 2016 Institute of Psychoanalysis.

  1. Inositol-phosphate signaling as mediator for growth and sexual reproduction in Podospora anserina.

    Science.gov (United States)

    Xie, Ning; Ruprich-Robert, Gwenaël; Chapeland-Leclerc, Florence; Coppin, Evelyne; Lalucque, Hervé; Brun, Sylvain; Debuchy, Robert; Silar, Philippe

    2017-09-01

    The molecular pathways involved in the development of multicellular fruiting bodies in fungi are still not well known. Especially, the interplay between the mycelium, the female tissues and the zygotic tissues of the fruiting bodies is poorly documented. Here, we describe PM154, a new strain of the model ascomycetes Podospora anserina able to mate with itself and that enabled the easy recovery of new mutants affected in fruiting body development. By complete genome sequencing of spod1, one of the new mutants, we identified an inositol phosphate polykinase gene as essential, especially for fruiting body development. A factor present in the wild type and diffusible in mutant hyphae was able to induce the development of the maternal tissues of the fruiting body in spod1, but failed to promote complete development of the zygotic ones. Addition of myo-inositol in the growth medium was able to increase the number of developing fruiting bodies in the wild type, but not in spod1. Overall, the data indicated that inositol and inositol polyphosphates were involved in promoting fruiting body maturation, but also in regulating the number of fruiting bodies that developed after fertilization. The same effect of inositol was seen in two other fungi, Sordaria macrospora and Chaetomium globosum. Key role of the inositol polyphosphate pathway during fruiting body maturation appears thus conserved during the evolution of Sordariales fungi. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Economic development and growth in transition countries

    NARCIS (Netherlands)

    Rusinova, D.T.

    2010-01-01

    The countries of Central and Eastern Europe and the former Soviet Union, commonly referred to as "transition countries", have undergone transformations unparalleled in recent economic history. This book concentrates on three aspects of the transition process: the factors driving growth, the effect

  3. Fostering inclusive growth | IDRC - International Development ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2017-05-12

    May 12, 2017 ... IDI provides a more nuanced assessment of economic progress than GDP. The report features a policy framework that outlines areas such as education, infrastructure, ethics, investment, entrepreneurship, and social protection as focus points for governments to improve their inclusive growth strategies.

  4. Developing, Implementing, and Evaluating a Condom Promotion Program Targeting Sexually Active Adolescents.

    Science.gov (United States)

    Alstead, Mark; Campsmith, Michael; Halley, Carolyn Swope; Hartfield, Karen; Goldblum, Gary; Wood, Robert W.

    1999-01-01

    Describes the development, implementation, and evaluation of an HIV prevention program promoting condom use among sexually active adolescents. It mobilized target communities to guide program development and implementation; created a mass media campaign to promote correct condom use; and recruited public agencies and organizations to distribute…

  5. The pharmaceuticalization of sexual risk: vaccine development and the new politics of cancer prevention.

    Science.gov (United States)

    Mamo, Laura; Epstein, Steven

    2014-01-01

    Vaccine development is a core component of pharmaceutical industry activity and a key site for studying pharmaceuticalization processes. In recent decades, two so-called cancer vaccines have entered the U.S. medical marketplace: a vaccine targeting hepatitis B virus (HBV) to prevent liver cancers and a vaccine targeting human papillomavirus (HPV) to prevent cervical and other cancers. These viruses are two of six sexually transmissible infectious agents (STIs) that are causally linked to the development of cancers; collectively they reference an expanding approach to apprehending cancer that focuses attention simultaneously "inward" toward biomolecular processes and "outward" toward risk behaviors, sexual practices, and lifestyles. This paper juxtaposes the cases of HBV and HPV and their vaccine trajectories to analyze how vaccines, like pharmaceuticals more generally, are emblematic of contemporary pharmaceuticalization processes. We argue that individualized risk, in this case sexual risk, is produced and treated by scientific claims of links between STIs and cancers and through pharmaceutical company and biomedical practices. Simultaneous processes of sexualization and pharmaceuticalization mark these cases. Our comparison demonstrates that these processes are not uniform, and that the production of risks, subjects, and bodies depends not only on the specificities of vaccine development but also on the broader political and cultural frames within which sexuality is understood. Copyright © 2013 Elsevier Ltd. All rights reserved.

  6. Potential contribution of progesterone receptors to the development of sexual behavior in male and female mice.

    Science.gov (United States)

    Desroziers, Elodie; Brock, Olivier; Bakker, Julie

    2017-04-01

    We previously showed that estradiol can have both defeminizing and feminizing effects on the developing mouse brain. Pre- and early postnatal estradiol defeminized the ability to show lordosis in adulthood, whereas prepubertal estradiol feminized this ability. Furthermore, we found that estradiol upregulates progesterone receptors (PR) during development, inducing both a male-and female-typical pattern of PR expression in the mouse hypothalamus. In the present study, we took advantage of a newly developed PR antagonist (ZK 137316) to determine whether PR contributes to either male- or female-typical sexual differentiation. Thus groups of male and female C57Bl/6j mice were treated with ZK 137316 or OIL as control: males were treated neonatally (P0-P10), during the critical period for male sexual differentiation, and females were treated prepubertally (P15-P25), during the critical period for female sexual differentiation. In adulthood, mice were tested for sexual behavior. In males, some minor effects of neonatal ZK treatment on sexual behavior were observed: latencies to the first mount, intromission and ejaculation were decreased in neonatally ZK treated males; however, this effect disappeared by the second mating test. By contrast, female mice treated with ZK during the prepubertal period showed significantly less lordosis than OIL-treated females. Mate preferences were not affected in either males or females treated with ZK during development. Taken together, these results suggest a role for PR and thus perhaps progesterone in the development of lordosis behavior in female mice. By contrast, no obvious role for PR can be discerned in the development of male sexual behavior. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. Development of sexual behavior in free-ranging female Japanese macaques.

    Science.gov (United States)

    Leca, Jean-Baptiste; Gunst, Noëlle; Vasey, Paul L

    2014-09-01

    We studied the development of sexual behaviors in female Japanese macaques (Macaca fuscata) living at Arashiyama, Japan, in a group where adult females routinely exhibit sexual interactions with both males and females. Our cross-sectional data on juvenile, adolescent, and adult females supported most of our predictions related to the learning hypothesis, which holds that adolescence serves to provide females with a period in which to practice adult female-like sexual behavioral patterns, including sexual solicitations, sexual mounts, and spatio-temporal coordination during consortships. We found evidence for a gradual acquisition of adult-like behavioral patterns (e.g., more frequent solicitations with body contact, more frequent complete mounts, more diverse solicitation patterns and complete mounting postures, and longer consortships involving prolonged inter-mount grasping behavior between partners), and a gradual disappearance of less effective immature behavioral patterns (e.g., less frequent non-contact solicitations, ambiguous mounting initiations, and incomplete mounts). We distinguished between three major categories of sexual behavioral patterns based on their speed of development, ranging from fast (e.g., diversity in mounting postures and genital stimulation during mounting) to slow (e.g., contact solicitations and grasping behavior between consortship partners), with some being intermediate (e.g., range of solicitation patterns and expression of complete mounts). This study showed that the emergence of both conceptive and non-conceptive adult sexual behaviors can be traced back to immature behavioral patterns in adolescent female Japanese macaques, with a major threshold occurring at the age of 4 years. © 2014 Wiley Periodicals, Inc.

  8. Questionnaire development and validity to measure sexual intention among youth in Malaysia

    Directory of Open Access Journals (Sweden)

    Noor Azimah Muhammad

    2017-02-01

    Full Text Available Abstract Background From the Theory of Planned Behaviour perspective, sexual intention is determined by a permissive attitude, perception of social norms and perceived self-efficacy in performing sexual activity. The aim of this study was to develop and validate the Youth Sexual Intention Questionnaire (YSI-Q, which was designed to measure sexual intention among youths in Malaysia. Methods A total of 25 items were developed based on literature reviews encompassing four main constructs: sexual intention, attitude, social norms and self-efficacy. The YSI-Q then underwent a validation process that included content and face validity, exploratory factor analysis (EFA, reliability analysis, and confirmatory factor analysis (CFA. This study was conducted on unmarried youths aged 18 to 22 years who were studying in colleges around Klang Valley, Malaysia. Results EFA supported the four factor structure, but five items were removed due to incorrect placement or low factor loading (<0.60. Internal reliability using Cronbach’s alpha ranged between 0.89 and 0.94. The CFA further confirmed the construct, convergent and discriminant validity of the YSI-Q with χ 2 = 392.43, df = 164, p < 0.001, χ 2/df = 2.40, CFI = 0.93 and TLI = 0.92 and RMSEA = 0.08. Conclusion The final set of YSI-Q consisted of 20 items measuring sexual intention (five items, attitude (five items, social norms (six items and self-efficacy (four items of practicing sexual activity. YSI-Q was shown to be a reliable and valid tool to be used among Malaysian youths.

  9. Evolution of development of vascular cambia and secondary growth.

    Science.gov (United States)

    Spicer, Rachel; Groover, Andrew

    2010-05-01

    Secondary growth from vascular cambia results in radial, woody growth of stems. The innovation of secondary vascular development during plant evolution allowed the production of novel plant forms ranging from massive forest trees to flexible, woody lianas. We present examples of the extensive phylogenetic variation in secondary vascular growth and discuss current knowledge of genes that regulate the development of vascular cambia and woody tissues. From these foundations, we propose strategies for genomics-based research in the evolution of development, which is a next logical step in the study of secondary growth.

  10. Development of Technology Transfer Economic Growth Metrics

    Science.gov (United States)

    Mastrangelo, Christina M.

    1998-01-01

    The primary objective of this project is to determine the feasibility of producing technology transfer metrics that answer the question: Do NASA/MSFC technical assistance activities impact economic growth? The data for this project resides in a 7800-record database maintained by Tec-Masters, Incorporated. The technology assistance data results from survey responses from companies and individuals who have interacted with NASA via a Technology Transfer Agreement, or TTA. The goal of this project was to determine if the existing data could provide indications of increased wealth. This work demonstrates that there is evidence that companies that used NASA technology transfer have a higher job growth rate than the rest of the economy. It also shows that the jobs being supported are jobs in higher wage SIC codes, and this indicates improvements in personal wealth. Finally, this work suggests that with correct data, the wealth issue may be addressed.

  11. Corruption and growth in developing countries

    OpenAIRE

    Lacroix, Jean

    2013-01-01

    Corruption is morally condemnable but what about its economical effect on the efficiency of on economy? Different transmission channels positively and negatively correlated with growth exist. The aim of this work is to catch the overall reality behind this impressively high number of transmission channels. Another task is to show the concrete consequences of corruption on a little economy like Haïti and what could be the consequences of the weaknesses induced by corruption. A presentation of ...

  12. Resources and Development: Structure and Growth

    OpenAIRE

    Syrquin Moshe

    2007-01-01

    The sustained increase in per capita product and the sweeping structural changes that characterize the epoch that Simon Kuznets (1966) defined as Modern Economic Grosth (MEG) were made possible by the substitution of inanimate power for animal power as a source of energy. Malthusian limits to growth were overcome by the pervasive application of science-based technology to production. The paper summarizes the main features of the structural transformation during MEG and the likely evolution of...

  13. The Relationship Between Financial Development and Economic Growth)

    OpenAIRE

    Afşar, Aslı

    2007-01-01

    The relation between the development of financial system and economic growth has been discussed for a long time. Financial system has been accepted as the most important of the economic system. The reason is that it is the center of transferring-process of funds which is needed most for economic growth. Mostly general economic success depends on the efficiency of the financial system. On the other hand, economic growth brings about increasing national income and causes a development in the in...

  14. Growth and project finance in the least developed countries

    OpenAIRE

    Lisbeth F. la Cour; Jennifer Müller

    2014-01-01

    This article examines the effects of project finance on economic growth in the least developed countries (LDC). Inspired by the neoclassical growth model we set up an econometric model to estimate the effects of project finance for a sample consisting of 38 of the least developed countries using data from the period 1994-2007. The results of our study suggest, that project finance has a significant positive effect on economic growth and therefore constitute an important source of ...

  15. Fungal metabolic plasticity and sexual development mediate induced resistance to arthropod fungivory.

    Science.gov (United States)

    Döll, Katharina; Chatterjee, Subhankar; Scheu, Stefan; Karlovsky, Petr; Rohlfs, Marko

    2013-11-22

    Prey organisms do not tolerate predator attack passively but react with a multitude of inducible defensive strategies. Although inducible defence strategies are well known in plants attacked by herbivorous insects, induced resistance of fungi against fungivorous animals is largely unknown. Resistance to fungivory is thought to be mediated by chemical properties of fungal tissue, i.e. by production of toxic secondary metabolites. However, whether fungi change their secondary metabolite composition to increase resistance against arthropod fungivory is unknown. We demonstrate that grazing by a soil arthropod, Folsomia candida, on the filamentous fungus Aspergillus nidulans induces a phenotype that repels future fungivores and retards fungivore growth. Arthropod-exposed colonies produced significantly higher amounts of toxic secondary metabolites and invested more in sexual reproduction relative to unchallenged fungi. Compared with vegetative tissue and asexual conidiospores, sexual fruiting bodies turned out to be highly resistant against fungivory in facultative sexual A. nidulans. This indicates that fungivore grazing triggers co-regulated allocation of resources to sexual reproduction and chemical defence in A. nidulans. Plastic investment in facultative sex and chemical defence may have evolved as a fungal strategy to escape from predation.

  16. Heterospecific exposure affects the development of secondary sexual traits in male zebra finches (Taeniopygia guttata).

    Science.gov (United States)

    Gehrold, Andrea; Leitner, Stefan; Laucht, Silke; Derégnaucourt, Sébastien

    2013-03-01

    In many animal species, social signals can affect the reproductive physiology and behaviour of conspecifics. In a few species that exhibit vocal learning, exposure to conspecific and sometimes heterospecific sounds can also influence their vocal development. Here we show that heterospecific exposure can affect the development of secondary sexual traits of male zebra finches (Taeniopygia guttata). In a first experiment, we trained young males with a passive playback of domesticated canary (Serinus canaria) song. Song playback enhanced the sexual development of the birds: they started to sing during the presentation of a video clip of a female earlier during development and exhibited secondary sexual plumage ornaments faster than males of the control group kept in silence. Two out of five birds exhibited clear evidence of imitation of canary song. In a second experiment, we raised young male finches with young male canaries in pairs until adulthood. Again, the live contact with a heterospecific companion affected the development of plumage ornaments in finches. We also observed some evidences of vocal convergence, both for calls and song. Moreover, young males of both species could recognize the call of their heterospecific companion when adults. These results suggest that heterospecific exposure can affect both the sexual and the vocal development of the zebra finch and can have long lasting effects. This article is part of a Special Issue entitled: insert SI title. Copyright © 2013 Elsevier B.V. All rights reserved.

  17. Developing an affirmative position statement on sexual and gender diversity for psychology professionals in South Africa

    Directory of Open Access Journals (Sweden)

    Cornelius J. Victor

    2017-06-01

    Full Text Available Background. Against the background of the dominance of patriarchy and heteronormativity in Africa and the resultant stigma, discrimination and victimisation of sexually and gender-diverse people, this article reports on the development of an affirmative position statement by the Psychological Society of South Africa (PsySSA for psychology professionals working with sexually and gender-diverse people. The position statement is an attempt to contribute positively to the de-stigmatisation, amongst psychology professionals, of all people with diverse sexual and gender identities. Objective. In documenting and reflecting on the process of developing the statement — a first on the African continent — the article aims to contribute to the potential resources available to others in their work on similar projects around the world. Design. Although initially intended to be relevant to the African continent, the position statement is appropriate to the South African context specifically, but developed in consultation with a range of stakeholders, also from other African countries. Results. Concerns expressed during stakeholder consultations, and thus taken into account in the development of the statement, include relevance to other African countries, negotiating the politics of representation and language, the importance of including gender and biological variance in addition to sexuality, and the need to be sensitive to how Western influence is constructed in some African contexts. Conclusion. Other national psychology organisations stand to benefit by ‘lessons learned’ during this country-specific process with global implications, especially with respect to broadening the lens from lesbian, gay, bisexual, transgender and intersex (LGBTI to sexual and gender diversity, as well as an acknowledgement of the multiple and fluid developmental pathways around sexuality and gender, in general.

  18. Age, growth rate and size at sexual maturity of Labeobarbus aeneus ...

    African Journals Online (AJOL)

    Of 193 L. aeneus collected by gillnetting, 96 were assessed for sexual maturity, and ages were estimated using scales (n = 143) and whole otoliths (n = 167). Whole otoliths were found to be the most appropriate method for ageing. Both males and females were present in all age classes, which ranged from 2 to 19 years.

  19. Age estimation, growth rate and size at sexual maturity of tigerfish ...

    African Journals Online (AJOL)

    A total of 206 tigerfish Hydrocynus vittatus, collected by angling in August 2005, 2006 and 2007, was assessed for sexual maturity and relative ages were estimated from 135 of these, using scales and whole and sectioned otoliths. Sectioned otoliths were the most appropriate method for ageing H. vittatus of up to 20 years ...

  20. Sex-specific growth in chicks of the sexually dimorphic Black-tailed Godwit

    NARCIS (Netherlands)

    Loonstra, A.H.J.; Verhoeven, M.A.; Piersma, T.

    2018-01-01

    Sexual size dimorphism (SSD) is common in birds and has been linked to various selectiveforces. Nevertheless, the question of how and when the sexes start to differentiatefrom each other is poorly studied. This is a critical knowledge gap, as sex differences ingrowth may cause different responses to

  1. Sexual dimorphism in size, age, maturation, and growth characteristics of boarfish (Capros aper) in the Northeast Atlantic

    DEFF Research Database (Denmark)

    Hüssy, Karin; Coad, Julie Olivia; Farrell, Edward D.

    2012-01-01

    stock with sexual dimorphism, where females are, on average, larger than males. No seasonal effects occur in size distribution and sex ratio, indicating that females and males stay together in shoals throughout the year. Females become increasingly dominant in abundance at larger sizes and older ages...... in abundance in the Northeast Atlantic. This study presents detailed biological information relevant to understanding stock structure and dynamics. Boarfish are a long-lived species that reach a maximum age of >30 years. The size distribution is skewed towards larger sizes, as expected from an unexploited....... There is no significant difference in length at maturity nor age at maturity between the two sexes, with L50 = 9.7 cm and A50 = 3.4 years. Growth is dimorphic following von Bertalanffy growth characteristics, with a common t = –2.897, but significantly different K and Linf values, where females have K = 0.145 and Linf...

  2. Bringing sexual and reproductive health in the urban contexts to the forefront of the development agenda: the case for prioritizing the urban poor.

    Science.gov (United States)

    Mberu, Blessing; Mumah, Joyce; Kabiru, Caroline; Brinton, Jessica

    2014-09-01

    Estimates suggest that over 90 % of population increase in the least developed countries over the next four decades will occur in urban areas. These increases will be driven both by natural population growth and rural-urban migration. Moreover, despite its status as the world's least urbanized region, the urban population in the sub-Saharan Africa region is projected to increase from under 40 % currently to over 60 % by 2050. Currently, approximately 70 % of all urban residents in the region live in slums or slum-like conditions. Sexual and reproductive health (SRH) risks for the urban poor are severe and include high rates of unwanted pregnancies, sexually transmitted infections, and poor maternal and child health outcomes. However, the links between poverty, urbanization, and reproductive health priorities are still not a major focus in the broader development agenda. Building on theoretical and empirical data, we show that SRH in urban contexts is critical to the development of healthy productive urban populations and, ultimately, the improvement of quality of life. We posit that a strategic focus on the sexual and reproductive health of urban residents will enable developing country governments achieve international goals and national targets by reducing health risks among a large and rapidly growing segment of the population. To that end, we identify key research, policy and program recommendations and strategies required for bringing sexual and reproductive health in urban contexts to the forefront of the development agenda.

  3. The Maestro (Mro gene is dispensable for normal sexual development and fertility in mice.

    Directory of Open Access Journals (Sweden)

    Lee Smith

    Full Text Available The mammalian gonad arises as a bipotential primordium from which a testis or ovary develops depending on the chromosomal sex of the individual. We have previously used DNA microarrays to screen for novel genes controlling the developmental fate of the indifferent embryonic mouse gonad. Maestro (Mro, which encodes a HEAT-repeat protein, was originally identified as a gene exhibiting sexually dimorphic expression during mouse gonad development. Wholemount in situ hybridisation analysis revealed Mro to be expressed in the embryonic male gonad from approximately 11.5 days post coitum, prior to overt sexual differentiation. No significant expression was detected in female gonads at the same developmental stage. In order to address its physiological function, we have generated mice lacking Maestro using gene targeting. Male and female mice homozygous for a Mro null allele are viable and fertile. We examined gonad development in homozygous male embryos in detail and observed no differences when compared to wild-type controls. Immunohistochemical analysis of homozygous mutant testes of adult mice revealed no overt abnormalities. Expression profiling using DNA microarrays also indicated no significant differences between homozygote embryonic male gonads and controls. We conclude that Maestro is dispensable for normal male sexual development and fertility in laboratory mice; however, the Mro locus itself does have utility as a site for insertion of transgenes for future studies in the fields of sexual development and Sertoli cell function.

  4. An in vivo model fish system to test chemical effects on sexual differentiation and development: exposure to ethinyl estradiol

    Science.gov (United States)

    Papoulias, Diana M.; Noltie, Douglas B.; Tillitt, Donald E.

    2000-01-01

    A model system was characterized which may be used as an in vivo screen for effects of chemicals or environmental mixtures on sexual differentiation and development of reproductive organs and gametes. We evaluated the effects of a model environmental estrogen, ethinyl estradiol (EE2), on the d-rR strain of medaka, Oryzias latipes, using a nano-injection exposure. Gonad histopathology indicated that a single injection of 0.5–2.5 ng EE2/egg can cause phenotypic sex-reversal of genetic males to females. Sex-reversals could be detected as early as 7 days post-hatch. Sex-reversed males had female-typical duct development and the secondary sex characteristics we measured were generally consistent with phenotype, with the exception of a few EE2-exposed XX and XY females which possessed ambiguous anal fins. Using discriminant analysis, we determined that the presence or absence of the secondary sex characteristic, a dorsal fin notch, was a very reliable indicator of gonadal sex. No instances of gonadal intersexes were observed. Ethinyl estradiol also appeared to reduce growth but not condition (weight-at-length) and exposed XX females appeared to have a higher incidence of atretic follicles relative to controls. Our results suggest that estrogenic chemicals may influence sexual differentiation and development and that the medaka model is well suited to assessing these effects.

  5. Wealth, welfare and sustainable growth and development

    Energy Technology Data Exchange (ETDEWEB)

    Moe, Thorvald

    2011-07-01

    This Policy Note discuses, based on modern development theory and wealth accounting, challenges for economic- and fiscal policies in resource-producing countries defined as countries - both developed and developing low income countries - which rely heavily on non-renewable or exhaustible natural wealth.(Author)

  6. Impact of Childhood Sexual Abuse on College Student Development: A Seven-Vectors Perspective

    Science.gov (United States)

    Goldberg, Daniel B.

    2016-01-01

    The application of theory in this article expanded on Chickering and Reisser's ([Chickering, A. W., 1993]) 7-vectors framework by considering the effects of childhood sexual abuse (CSA) on the normal experience of student development in higher education. The article includes an overview of the prevalence and effects of CSA and a case study of a…

  7. Development and characterization of microsatellite markers in the sexual-apomictic complex Taraxacum officinale (dandelion)

    NARCIS (Netherlands)

    Falque, M.; Keurentjes, J.J.B.; Bakx-Schotman, J.M.T.; Van Dijk, P.J.

    1998-01-01

    Microsatellite markers were developed in Taraxacum officinale to study gene flow between sexual and apomictic plants and to identify clones. Twenty five thousand genomic DNA clones were hybridized with a (CT)(12)D probe. The density of (GA/CT)(n) repeats was estimated at one every 61 kb in the T.

  8. Effect of cytosine arabinoside on cerebellar neurofilaments during development: A sexual dimorphism

    Directory of Open Access Journals (Sweden)

    Christos Koros

    2014-01-01

    These data show that the neurofilament cytoskeleton in the developing rat cerebellum exhibits resistance to AraC that appears sexually dimorphic. In young males the resistance is exemplified by a lack of responsiveness, whereas in juvenile females it is presented by an androgenization-sensitive NF upregulation.

  9. Development of an adolescent inpatient sexual abuse group: application of Lewin's model of change.

    Science.gov (United States)

    Riddle, C R

    1994-01-01

    The development and implementation of an adolescent sexual abuse group on an inpatient psychiatric unit is described. Steps of Kurt Lewin's model of change are used as a framework for this planned change. Specific issues concerning group procedure and process are detailed. Recommendations for this group and broader use of the Lewin model are included.

  10. The Development and Psychometric Assessment of the Adolescent Sexual Coercion Risk Scale

    Science.gov (United States)

    Bramsen, Rikke Holm; Lasgaard, Mathias; Elklit, Ask; Koss, Mary P.

    2011-01-01

    The objective of this study was to develop a psychometric measure of risk for sexual victimization from adolescent peers. Items were generated on the basis of the literature and on consultations with a multidisciplinary group of key informants. The items were administered to a sample of 327 female Grade-9 students and examined using exploratory…

  11. Let's Talk about Sex: Development of a Sexual Health Program for Nepali Women

    Science.gov (United States)

    Kaufman, Michelle R.; Harman, Jennifer J.; Shrestha, Deepti Khati

    2012-01-01

    The purpose of this study was to develop and test the feasibility of conducting a sexual health intervention for women in Nepal, a country with high political and economic instability and strong patriarchal systems. Of the 88 women enrolled, 100% retention was obtained over three sessions, and 85% completed a 1-month follow-up. Recruitment was so…

  12. Discovering Sexual Health Conversations between Adolescents and Youth Development Professionals

    Science.gov (United States)

    Gupta, Niodita; Chandak, Aastha; Gilson, Glen; Pelster, Aja Kneip; Schober, Daniel J.; Goldsworthy, Richard; Baldwin, Kathleen; Fortenberry, J. Dennis; Fisher, Christopher

    2015-01-01

    Youth development professionals (YDPs) working at community-based organizations are in a unique position to interact with the adolescents because they are neither parents/guardians nor teachers. The objectives of this study were to explore qualitatively what sexual health issues adolescents discuss with YDPs and to describe those issues using the…

  13. State Legislative Developments on Campus Sexual Violence: Issues in the Context of Safety

    Science.gov (United States)

    Morse, Andrew; Sponsler, Brian A.; Fulton, Mary

    2015-01-01

    NASPA--Student Affairs Administrators in Higher Education and Education Commission of the States (ECS) have partnered to address legislative developments and offer considerations for leaders in higher education and policy on two top-level safety issues facing the higher education community: campus sexual violence and guns on campus. The first in a…

  14. Research on Adolescent Sexual Orientation: Development, Health Disparities, Stigma, and Resilience

    Science.gov (United States)

    Saewyc, Elizabeth M.

    2011-01-01

    The decade between 1998 and 2008 saw rapid increases in research on adolescent sexual orientation development and related health issues, both in the quantity and in the quality of studies. While much of the research originated in North America, studies from other countries also contributed to emerging understanding of developmental trajectories…

  15. Effectiveness of structured teaching programme on knowledge regarding sexual health among young adults

    OpenAIRE

    Atul Kumar; Mahalingam Venkateshan; Selvi

    2016-01-01

    Background: Adulthood is the pinnacle of all stages of human growth and development. Sexuality plays the axial role in all the spheres of human life. Individual's health can be regarded on the reciprocal function of his sexuality and sexual practices. Abnormal sexuality results in deviation in physical, physiological, psychological and even economical disturbances. The main aim of the study was to evaluate the effectiveness of structured teaching programme on knowledge regarding sexual health...

  16. Suzie's Mommy Is Having a Baby: Don't Freak out! Healthy Sexuality Development in Young Children

    Science.gov (United States)

    Sciaraffa, Mary

    2012-01-01

    Is it the teacher's job to assist children in developing a healthy sexual identity in early childhood? A healthy sexual identity is developed over the course of a lifetime through the "process of acquiring information and forming attitudes, beliefs, and values about such important topics as identity, relationships, and intimacy." Teachers may feel…

  17. Men's Responses to Women's Sexual Refusals: Development and Construct Validity of a Virtual Dating Simulation of Sexual Aggression.

    Science.gov (United States)

    Abbey, Antonia; Pegram, Sheri E; Woerner, Jacqueline; Wegner, Rhiana

    2018-01-01

    To provide evidence regarding the construct validity of a sexual aggression proxy in which male participants go on multiple virtual dates with a woman. A unique strength of this proxy is participants' opportunity to make choices throughout the simulation about how they interact with their virtual date. These decisions determine their exposure to the female agent's sexual refusals. Piloting included focus groups (n = 82), surveys (n = 95), and cognitive interviews (n = 32). To establish construct validity, 87 male participants completed two separate sessions: 1) an online survey with measures of discriminant and convergent validity; and 2) a lab session in which they went on multiple dates that included nonsexual options, sexual options which the female agent accepted, and sexual options she refused. Sexual aggression was operationalized as the total number of sexual refusals that participants' received. There was strong correlational evidence for discriminant and convergent validity. As hypothesized, there were some differences in the risk factors associated with refusals received on casual as compared to steady dates. Additionally, the number of refusals received was associated with the types of thoughts and actions commonly reported by perpetrators. This simulation provides a new approach for examining sexual aggression in controlled experiments that vary factors within the simulation such as the man's and woman's intoxication and past sexual history. Because what happens is based on each individual's responses, it could be adapted for use in prevention and treatment programs.

  18. Growth and development after hematopoietic cell transplant in children.

    Science.gov (United States)

    Sanders, J E

    2008-01-01

    Hematopoietic cell transplantation (HCT) following high-dose chemotherapy or chemoradiotherapy for children with malignant or nonmalignant hematologic disorders has resulted in an increasing number of long-term disease-free survivors. The preparative regimens include high doses of alkylating agents, such as CY with or without BU, and may include TBI. These agents impact the neuroendocrine system in growing children and their subsequent growth and development. Children receiving high-dose CY or BUCY have normal thyroid function, but those who receive TBI-containing regimens may develop thyroid function abnormalities. Growth is not impacted by chemotherapy-only preparative regimens, but TBI is likely to result in growth hormone deficiency and decreased growth rates that need to be treated with synthetic growth hormone therapy. Children who receive high-dose CY-only have normal development through puberty, whereas those who receive BUCY have a high incidence of delayed pubertal development. Following fractionated TBI preparative regimens, approximately half of the patients have normal pubertal development. These data demonstrate that the growth and development problems after HCT are dependent upon the preparative regimen received. All children should be followed for years after HCT for detection of growth and development abnormalities that are treatable with appropriate hormone therapy.

  19. Role of sexual abuse in development of conversion disorder: case report.

    Science.gov (United States)

    Sobot, V; Ivanovic-Kovacevic, S; Markovic, J; Misic-Pavkov, G; Novovic, Z

    2012-02-01

    Described case report speaks in favour of the relation between childhood sexual abuse with the development of conversion disorder. Following Salmonella poisoning, adolescent, at the age of 16, develops series of severe somatic symptoms. Results of diagnostic procedures excluded organic foundation of the symptoms; diagnosis of conversion disorder is established. Soon, patient's problems stop abruptly and spontaneously, and the aetiology of the mental disorder remains unexplained. Six years later, adolescent reveals for the first time data about the childhood sexual abuse during the forensic evaluation (within the court process related to the request for compensation for the complications which occurred following the Salmonella infection). During the forensic evaluation, we had insight into the previous medical history, while an interview, psychological and psychiatric exploration was conducted with the examinee. Data about the sexual abuse retrospectively explain the dynamics of the development of conversion disorder. The described case indicates that sexual abuse of children and adolescents frequently remains unrecognized, which has sequels for treatment and prevention of subsequent consequences for mental health. It is important to emphasize the significance of examining history of abuse during the diagnostic of certain mental disorders. Forensic implications of the case have not been discussed in details for the needs of this report.

  20. ISLAMIC FINANCE DEVELOPMENT AND ECONOMIC GROWTH: EMPIRICAL EVIDENCE FROM TURKEY

    Directory of Open Access Journals (Sweden)

    Mustapha JOBARTEH

    2017-02-01

    Full Text Available This work is a study on Islamic finance development and economic growth nexus for Turkey. It employs the econometric methods of unit root, co-integration, and Granger causality in a VECM framework; and the results, which are robust to all measures of Islamic finance development, show a unidirectional short and long run causality from Islamic finance development to economic growth. Hence, it is recommended that policy makers increase their efforts in promoting Islamic finance in Turkey.

  1. Problems of urban development and growth

    Science.gov (United States)

    Gerlach, A. C.; Wray, J. R.

    1972-01-01

    The increase in the density of human population in urban areas and the effects on various aspects of the environment are discussed. The application of remote sensors to measure, analyze, and predict urban changes and their environmental impact is described. Examples of urban area mapping by aerial photography are included. The methods which have been developed to acquire, analyze, utilize, and preserve remotely sensed data on urban development are presented.

  2. Irradiation growth of Zircaloy (LWBR) development program

    International Nuclear Information System (INIS)

    Williard, H.J.

    1984-01-01

    Irradiation growth of recrystallized annealed (RXA) Zircaloy is divided into four stages and a model is presented to account for each stage. Stage I is a short time, low-strain transient caused by the accumulation of point defects, small interstitial loops, and vacancy clusters. Stage II is a quasi-steady-state region of relatively low strain rate during which the loops grow and intrinsic dislocations climb. Stage III is a transient during which the strain rate increases due to the production and motion of irradiation-induced dislocation lines. Stage IV is a high-strain-rate, steady-state region during which nonrecoverable strain is caused predominantly by glide of the irradiationinduced dislocations. The proposed model is based on two new mechanisms: (1) direct production of an interstitial dislocation loop accompanied by a vacancy cluster in the primary damage event, and (2) production of dislocations due to the activation of Frank-Read sources by internal stresses caused by interaction of the loops with themselves and with intrinsic (cold work) dislocations. Nonconservative, recoverable strain is due to climb of all dislocations, whereas conservative, nonrecoverable strain is caused by glide of irradiation-induced and intrinsic dislocations under the action of the internal stress. The conservative strain follows a (1-3f) texture dependence

  3. Networks: Innovation, Growth and Sustainable Development

    Directory of Open Access Journals (Sweden)

    Peter Johnston

    2013-05-01

    Full Text Available The emergence of the Internet as a measureable manifestation of our social and economic relationships changed the domination of networks in our lives. From about 2000, the internet has allowed us to study and understand the type of networks in which we live, and to model their behaviour. The Internet has fundamentally changed the distribution of wealth. The rich became richer simply because of the larger scale of the trading network and stretched national wealth distributions. Network effects are therefore likely to be responsible for much of the perceived increases in inequalities in the last 20-30 years, and policies to tackle poverty must therefore address the extent to which the poor can engage with society's networks of wealth creation. The greatest challenge to continued growth and prosperity, and therefore to peace and justice, is climate change. The potential cost of inaction on climate change could be as high. Our self-organising social networks have structured our societies and economies, and are now reflected in our technology networks. We can now replicate their evolution in computer simulations and can therefore better assess how to deal with the greatest challenges facing us in the next few decades.

  4. Abnormal cortical development after premature birth shown by altered allometric scaling of brain growth.

    Directory of Open Access Journals (Sweden)

    Olga Kapellou

    2006-08-01

    Full Text Available We postulated that during ontogenesis cortical surface area and cerebral volume are related by a scaling law whose exponent gives a quantitative measure of cortical development. We used this approach to investigate the hypothesis that premature termination of the intrauterine environment by preterm birth reduces cortical development in a dose-dependent manner, providing a neural substrate for functional impairment.We analyzed 274 magnetic resonance images that recorded brain growth from 23 to 48 wk of gestation in 113 extremely preterm infants born at 22 to 29 wk of gestation, 63 of whom underwent neurodevelopmental assessment at a median age of 2 y. Cortical surface area was related to cerebral volume by a scaling law with an exponent of 1.29 (95% confidence interval, 1.25-1.33, which was proportional to later neurodevelopmental impairment. Increasing prematurity and male gender were associated with a lower scaling exponent (p < 0.0001 independent of intrauterine or postnatal somatic growth.Human brain growth obeys an allometric scaling relation that is disrupted by preterm birth in a dose-dependent, sexually dimorphic fashion that directly parallels the incidence of neurodevelopmental impairments in preterm infants. This result focuses attention on brain growth and cortical development during the weeks following preterm delivery as a neural substrate for neurodevelopmental impairment after premature delivery.

  5. The impact of sexual abuse on female development: Lessons from a multigenerational, longitudinal research study

    Science.gov (United States)

    Noll, Jennie G.; Putnam, Frank W.

    2013-01-01

    This is a report on the research design and findings of a 23-year longitudinal study of the impact of intrafamilial sexual abuse on female development. The conceptual framework integrated concepts of psychological adjustment with theory regarding how psychobiological factors might impact development. Participants included 6- to 16-year-old females with substantiated sexual abuse and a demographically similar comparison group. A cross-sequential design was used and six assessments have taken place, with participants at median age 11 at the first assessment and median age 25 at the sixth assessment. Mothers of participants took part in the early assessments and offspring took part at the sixth assessment. Results of many analyses, both within circumscribed developmental stages and across development, indicated that sexually abused females (on average) showed deleterious sequelae across a host of biopsychosocial domains including: earlier onsets of puberty, cognitive deficits, depression, dissociative symptoms, maladaptive sexual development, hypothalamic–pituitary–adrenal attenuation, asymmetrical stress responses, high rates of obesity, more major illnesses and healthcare utilization, dropping out of high school, persistent psottraumatic stress disorder, self-mutilation, Diagnostic and Statistical Manual of Mental Disorders diagnoses, physical and sexual revictimization, premature deliveries, teen motherhood, drug and alcohol abuse, and domestic violence. Offspring born to abused mothers were at increased risk for child maltreatment and overall maldevelopment. There was also a pattern of considerable within group variability. Based on this complex network of findings, implications for optimal treatments are elucidated. Translational aspects of extending observational research into clinical practice are discussed in terms that will likely have a sustained impact on several major public health initiatives. PMID:23786689

  6. Symbiotic regulation of plant growth, development and reproduction

    Science.gov (United States)

    Russell J. Rodriguez; D. Carl Freeman; E. Durant McArthur; Yong Ok Kim; Regina S. Redman

    2009-01-01

    The growth and development of rice (Oryzae sativa) seedlings was shown to be regulated epigenetically by a fungal endophyte. In contrast to un-inoculated (nonsymbiotic) plants, endophyte colonized (symbiotic) plants preferentially allocated resources into root growth until root hairs were well established. During that time symbiotic roots expanded at...

  7. The Role of Stock Market Development on Economic Growth in ...

    African Journals Online (AJOL)

    African Research Review ... Abstract. This study investigated the role of stock market development on economic growth of Nigeria using a 15-year time series data from 1994 - 2008. ... This result implies that liquidity has propensity to spur economic growth in Nigeria and that market capitalization influences market liquidity.

  8. Growth, development, and behavior: confronting the issues of international adoption.

    Science.gov (United States)

    Baldwin, Shelly

    2011-02-01

    In evaluating children who have been adopted internationally, health care providers must consider the psychosocioemotional risk factors these children bring with them that ultimately affect their physical growth, development, and emotional, behavioral, and cognitive functioning. This third-in-a-series article explores these considerations and offers information regarding growth and developmental delays and the potential for behavioral and psychosocial concerns.

  9. The Role of Stock Market Development on Economic Growth in ...

    African Journals Online (AJOL)

    growth of Nigeria using a 15-year time series data from 1994-2008. The method of analysis used is Ordinary Least Square (OLS) techniques. The study measures the relationship between stock market development indices and economic growth. The stock market capitalization ratio was used as a proxy for market size while ...

  10. health needs sustainable development, not more economic growth

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. HEALTH NEEDS SUSTAINABLE DEVELOPMENT, NOT MORE ECONOMIC GROWTH. The pursuit of carbon-emitting economic growth has not provided economic and social stability – key determinants of health - for much of the world's population. Better health for all ...

  11. International Trade as an Engine of Growth in Developing Countries ...

    African Journals Online (AJOL)

    This study examines international trade as an engine of growth in developing countries, a case study of Nigeria. A review of the literature reveals that countries that are more open to international trade tends to experience higher growth rate and per-capital income than countries who do not trade or closed economy.

  12. The Use of Twitter for Professional Growth and Development

    Science.gov (United States)

    Gerstein, Jackie

    2011-01-01

    Twitter, the micro blogging tool, has seen unprecedented growth in the past year and is expected to continue into the future. Twitter's power, engagement, and popularity lie in its endless networking opportunities. Its potential as a venue for professional growth and development needs to be explored, discussed, and ultimately used as such. A brief…

  13. Africa's Growth and Development Strategies: A Critical Review ...

    African Journals Online (AJOL)

    At independence in the late 1950s and early 1960s, there were high hopes about the growth prospects of the new politically independent. African states. Economic conditions, such as per capita real income, were comparable to other developing countries like South Korea and. Taiwan. By the mid-1970s, the growth profile ...

  14. Remittances, financial development and economic growth: Empirical evidence from Lesotho

    Directory of Open Access Journals (Sweden)

    Athenia Bongani Sibindi

    2014-11-01

    Full Text Available Increasingly remittances now constitute a great source of foreign currency inflows for many developing countries. In some instances remittances have outpaced the growth of foreign direct investment (FDI. Amongst others, remittances can be used as a vehicle of savings mobilisation as well as fostering the supply of credit by providing liquidity to the market. In this article we investigate the causal relationship between the remittances, financial development and economic growth in Lesotho for the period 1975 to 2010. We make use of per capita remittances, real per capita broad money supply and real per capita growth domestic product as the proxies for remittances, financial development and economic growth respectively. We then test for cointegration amongst the variables by applying the Johansen procedure and then test for Granger causality based on the vector error correction model (VECM. Our results confirm the existence of at least one cointegrating relationship and also indicate that the direction of causality runs from remittances to the economy without feedback. The results also suggest that financial development Granger causes economic growth without feedback which is consistent with ‘supply-leading’ growth hypothesis. The results also confirm a causal relationship running from financial development to remittances without feedback. The results also lend credence to the “complementarity’ hypothesis in that, remittances complement rather than substitute financial development in bringing about economic growth.

  15. How Stock Markets Development Affect Endogenous Growth Theory

    Directory of Open Access Journals (Sweden)

    Najeb Masoud

    2013-10-01

    Full Text Available This paper can bedescribed as a significant exploratory study that will provide a significantcontribution to knowledge to consider crucial issues which need to be barriersto understanding or a temptation/ requirement to judge some practices as‘better’ than others for stock market development effective approach andimplement successful stock market performance and economic growth. Recentanalysis of the link between financial development and growth, gained frominsights acquired as a result of using the technique of endogenous growthmodels, has illustrated that growth without exogenous technical progress andthat growth rates could be related to technology, income distribution andinstitutional arrangements. This provides the theoretical background thatempirical studies have lacked; illustrating that financial intermediationaffects the level of economic growth. Resulting models have provided newimpetus to empirical research of the effects of financial development. Thebirth of the new endogenous growth theory has facilitated the development ofimproved growth models where the long-term rate could be affected by a numberof elements. These included technology, education and health policies in theprocess of economic development, capital accumulation, government policies andinstitutional activities in the role of financial development in economicgrowth.

  16. Population growth and development: the case of Bangladesh.

    Science.gov (United States)

    Nakibullah, A

    1998-04-01

    In a poor, overly populated country such as Bangladesh, some believe that a high rate of population growth is a cause of poverty which impedes economic development. Population growth would therefore be exogenous to economic development. However, others believe that rapid population growth is a consequence rather than a cause of poverty. Population growth is therefore endogenous to economic development. Findings are presented from an investigation of whether population growth has been exogenous or endogenous with respect to Bangladesh's development process during the past 3 decades. The increase in per capita real gross domestic product (GDP) is used as a measure of development. Data on population, real GDP per capita, and real investment share of GDP are drawn from the Penn World Table prepared by Summers and Heston in 1991. The data are annual and cover the period 1959-90. Analysis of the data indicate that population growth is endogenous to Bangladesh's development process. These findings are reflected both in the Granger causality tests and the decompositions of variances of detrended real GDP per capita and population growth.

  17. Sexuality and Sexual Rights in Muslim Societies

    OpenAIRE

    Liz Ercevik Amado

    2009-01-01

    In August 2008, the Coalition for Sexual and Bodily Rights in Muslim Societies (CSBR) organized the CSBR Sexuality Institute, the first international Institute on sexuality and sexual rights in Muslim societies in Malaysia. Liz Amado presents how the Institute expanded the discourse, knowledge and thinking around sexuality in Muslim societies, as well as providing a unique space for the much needed exchange of information and experience among sexual rights advocates. Development (2009) 52, 59...

  18. Growth & development of Indian children adopted in Sweden.

    Science.gov (United States)

    Proos, Lemm A

    2009-11-01

    More than 6800 children from India have been adopted in Sweden over the last four decades. At arrival many were undernourished and suffered from infectious diseases. Catch-up growth was common. Unexpectedly, cases of early pubertal development were subsequently reported. In order to investigate the growth and development of adopted children more in detail we studied 114 children adopted from India prospectively during two years. The majority were stunted at arrival and caught up in height and weight after two years. Psychomotor retardation and common infections diminished fairly soon. Those that were stunted did not attain the higher catch-up levels of those not stunted at arrival. Low birthweight also limited the degree of catch-up growth. 107 girls were analysed retrospectively in another study. The median menarcheal age was 11.6 yr (range 7.3-14.6 yr) which is significantly earlier than the mean in Swedish and privileged Indian girls (13.0 and 12.4-12.9 yr, respectively). The pubertal linear growth component was normal in duration and magnitude but likewise started 1.5 yr earlier. The final height/age was 154 cm (-1.4 SDS) and the weight/age 46.9 kg (-1.1 SDS) 8 per cent were 145 cm or shorter. Stunting limited catch-up growth and final height. Those that were most stunted at arrival, and had the fastest catch-up growth, had the earliest menarche. Good maternal and child nutrition is necessary for full expression of a child's growth potential. What is lost in growth early in life can only partially be recovered by catch-up growth. Such growth is associated with risk for early pubertal development which abbreviates the childhood growth period and limits final height. The mechanism underlying the early pubertal development, and the optimal management of nutrition rehabilitation after chronic malnutrition, need to be clarified by further studies.

  19. Histone deacetylation during brain development is essential for permanent masculinization of sexual behavior.

    Science.gov (United States)

    Matsuda, Ken Ichi; Mori, Hiroko; Nugent, Bridget M; Pfaff, Donald W; McCarthy, Margaret M; Kawata, Mitsuhiro

    2011-07-01

    Epigenetic histone modifications are emerging as important mechanisms for conveyance of and maintenance of effects of the hormonal milieu to the developing brain. We hypothesized that alteration of histone acetylation status early in development by sex steroid hormones is important for sexual differentiation of the brain. It was found that during the critical period for sexual differentiation, histones associated with promoters of essential genes in masculinization of the brain (estrogen receptor α and aromatase) in the medial preoptic area, an area necessary for male sexual behavior, were differentially acetylated between the sexes. Consistent with these findings, binding of histone deacetylase (HDAC) 2 and 4 to the promoters was higher in males than in females. To examine the involvement of histone deacetylation on masculinization of the brain at the behavioral level, we inhibited HDAC in vivo by intracerebroventricular infusion of the HDAC inhibitor trichostatin A or antisense oligodeoxynucleotide directed against the mRNA for HDAC2 and -4 in newborn male rats. Aspects of male sexual behavior in adulthood were significantly reduced by administration of either trichostatin A or antisense oligodeoxynucleotide. These results demonstrate that HDAC activity during the early postnatal period plays a crucial role in the masculinization of the brain via modifications of histone acetylation status.

  20. REFLECTIONS ON THE GROWTH AND DEVELOPMENT OF ...

    African Journals Online (AJOL)

    Shittu

    Islamic philosophy went through stages before finally standing on its own. ... believes this development occurs by a dialectical process, that is, a process through .... human ability. 13. Ibn Sina however went further in later life to distinguish between Peripatetic philosophy and what he called “Oriental philosophy”. (al-hikmah ...

  1. Economic development, growth, institutions and geography

    NARCIS (Netherlands)

    Bhupatiraju, S.; Verspagen, B.

    2013-01-01

    In this paper, we test the Rodrik et al (2004) framework to explain differences in development levels across countries by using a broader set of definitions for institutions, geography and economic variables. We use a multi-faceted database to measure institutions in an attempt to go beyond the

  2. Financial Development and Inclusive Growth in Nigeria: A Threshold Analysis

    Directory of Open Access Journals (Sweden)

    Taofeek Olusola Ayinde

    2016-10-01

    Full Text Available This study investigates the relationship between financial development and inclusive growth in Nigeria for the period 1980 – 2013. The technique of analysis is the quantile regression; which is to obtain a threshold for which the former impacts on the latter. The result shows a threshold level of 90th percentile. Interestingly, the study also found that the impact of financial development on inclusive growth depends on the measure of the former up to the threshold level and not beyond. Through a granger causality test, the direction of causality is through the inclusive growth rather than through financial development; through the financial deepening measure. While the study found that either a low level or high level of openness on trade and capital investment are desirable for inclusive growth in Nigeria, the results also reveal that government involvement in the workings of the Nigeria economy and financial openness are sensitive to the pattern of financial development. With financial deepening, both are negatively related to inclusive growth but positively related to inclusive growth when financial widening is considered. This suggests that government intervention in the activities of the private sector is detrimental when the latter are to drive financial development process. However, the involvement of government in ensuring the appropriate level of financial widening, through the central bank operations, produces a positive impact on growth.

  3. Financial Development Following Economic Growth: The Chinese Case

    Directory of Open Access Journals (Sweden)

    Chan il Park

    2003-06-01

    Full Text Available The purpose of this paper is to investigate the relationship between financial development and economic growth based on Chinese experiences during the period of 1979~2000. This study places more emphasis on the causality running from economic growth to financThe purpose of this paper is to investigate the relationship between financial development and economic growth based on Chinese experiences during the period of 1979~2000. This study places more emphasis on the causality running from economic growth to financial development contrary to the mainstream view, which asserts that the well-functioning financial systems exert a large positive impact on economic growth via two channels- capital accumulation and technological innovations. The reverse causality is postulated by considering two factors in developments of the country's financial system. Firstly, this paper argues that the rapid accumulation of financial assets and the remarkable expansion of the financial system during the examined period are due primarily to income rises and changes in industrial structures rather than inefficient financial reforms. Secondly, it is recognized in this study that various financial reform measures undertaken by the state since 1994 are emerged endogenously in response to Chinese financial disorders and macroeconomic imbalances built up during the 1979~93 period. This line of thinking is not following the mainstream view in which financial reforms are regarded as policy variables (or exogenous variables in promoting economic growth. These two factors imply that the causality may run from economic growth to financial development at least in China.

  4. In ovo exposure to o,p -DDE affects sexual development but not sexual differentiation in Japanese medaka (Oryzias latipes).

    Science.gov (United States)

    Papoulias, D.M.; Villalobos, Sergio A.; Meadows, J.; Noltie, Douglas B.; Giesy, J.P.; Tillitt, D.E.

    2003-01-01

    Despite being banned in many countries, dichlorodiphenyltrichloroethane (DDT) and its metabolites dichlorodiphenyldichloroethylene (DDE) and dichlorodiphenyldichloroethane (DDD) continue to be found in fish tissues at concentrations of concern. Like o,p -DDT, o,p -DDE is estrogenic and is believed to exert its effects through binding to the estrogen receptor. The limited toxicologic data for o,p -DDE suggest that it decreases fecundity and fertility of fishes. We conducted an egg injection study using the d-rR strain of medaka and environmentally relevant concentrations of o,p -DDE to examine its effects on sexual differentiation and development. The gonads of exposed fish showed no evidence of sex reversal or intersex. However, other gonad abnormalities occurred in exposed individuals. Females exhibited few vitellogenic oocytes and increased atresia. Male testes appeared morphologically normal but were very small. Gonadosomatic index values for both sexes were lower for exposed fish. Our observations of abnormal female and very small male gonads after in ovo o,p -DDE exposure may be indicative of effects on early endocrine processes important for normal ovarian and testicular development.

  5. Teenagers in the United States: sexual activity, contraceptive use, and childbearing, national survey of family growth 2006-2008.

    Science.gov (United States)

    Abma, Joyce C; Martinez, Gladys M; Copen, Casey E

    2010-06-01

    This report presents national estimates of sexual activity, contraceptive use, and births among males and females 15-19 years of age in the United States in 2006-2008 from the National Survey of Family Growth (NSFG). Selected data are also presented from the 1988, 1995, and 2002 NSFGs, and from the 1988 and 1995 National Survey of Adolescent Males (NSAM), conducted by the Urban Institute. Descriptive tables of numbers and percents are presented and discussed. Data were collected through in-person interviews of the household population in the United States, conducted between July 2006 and December 2008. Interviews were conducted with 7,356 females-1,381 of whom were teenagers--and 6,140 males--1,386 of whom were teenagers-for a total of 2,767 teenagers. The overall response rate for the 2006-2008 NSFG was 75%. The response rate for female teenagers was 77% and for male teenagers 75%. In 2006-2008, about 42% of never-married female teenagers (4.3 million), and about 43% of never-married male teenagers (4.5 million) had had sexual intercourse at least once. These levels of sexual experience have not changed significantly from 2002, the last time the NSFG collected these data. Among never-married teenagers, 79% of females and 87% of males used a method of contraception at first sex. With a few exceptions, teenagers' use of contraceptives has changed little since 2002, and the condom remained the most commonly used method. One exception was an increase in the use of condoms and the use of a condom combined with a hormonal contraceptive (dual method use) among males. Another exception was a significant increase in the percent of female teenagers who had ever used periodic abstinence, or the "calendar rhythm" method. This method had been used by 17% of female teenagers in 2006-2008.

  6. Development of a minimal growth medium for Lactobacillus plantarum.

    Science.gov (United States)

    Wegkamp, A; Teusink, B; de Vos, W M; Smid, E J

    2010-01-01

    A medium with minimal requirements for the growth of Lactobacillus plantarum WCFS was developed. The composition of the minimal medium was compared to a genome-scale metabolic model of L. plantarum. By repetitive single omission experiments, two minimal media were developed: PMM5 (true minimal medium) and PMM7 [a pseudominimal medium, supporting proper biomass formation of 350 mg l(-1) dry weight (DW)]. The specific growth rate of L. plantarum on PMM7 was found to be 50% and 63% lower when compared to growth on established growth media (chemically defined medium and MRS, respectively). Using a genome-scale metabolic model of L. plantarum, it was predicted that PMM5 and PMM7 would not support the growth of L. plantarum. This is because the biosynthesis of para-aminobenzoic acid (pABA) was predicted to be essential for growth. The discrepancy in simulated growth and experimental growth on PMM7 was further investigated for pABA; a molecule which plays an important role in folate production. The growth performance and folate production were determined on PMM7 in the presence and absence of pABA. It was found that a 12,000-fold reduction in folate pools exerted no influence on formation of biomass or growth rate of L. plantarum cultures when grown in the absence of pABA. Largely reduced folate production pools do not have an effect on the growth of L. plantarum, showing that L. plantarum makes folate in a large excess. These experiments illustrate the importance of combining genome-scale metabolic models with growth experiments on minimal media.

  7. Asynchrony in craniomandibular development and growth in Enhydra lutris nereis (Carnivora: Mustelidae): Are southern sea otters born to bite?

    Science.gov (United States)

    Law, Chris J; Baliga, Vikram B.; Tinker, M. Tim; Mehta, Rita S.

    2017-01-01

    Weaning represents a major ontogenetic dietary shift in southern sea otters (Enhydra lutris nereis), as juveniles must transition from depending on mother’s milk to independently processing hard-shelled invertebrates. When the skulls of juveniles have reached sufficient maturity to transition to a durophagous diet remains to be investigated. Here, we conducted a comprehensive analysis of skull development and growth and sexual dimorphism using geometric morphometric approaches in 204 southern sea otter skulls. We found that southern sea otters of both sexes exhibit dramatic changes in cranial and mandibular shape and size over ontogeny. Although the majority of these changes occur in the pup stage, full development and growth of the skull does not occur until well after weaning. We hypothesize that the slower maturation of the crania of newly weaned juveniles serves as a handicap by constraining jaw adductor muscle size, biting ability and feeding on hard-shelled prey. In our analysis of sexual dimorphism, we found significant sexual shape and size dimorphism in adult craniomandibular morphology that arose through differences in developmental and growth rates and duration. We postulate that males are selected to attain mature crania faster to presumably reach adult biting ability sooner, gaining a competitive advantage in obtaining food and in male–male agonistic interactions.

  8. Framework for Creating a Smart Growth Economic Development Strategy

    Science.gov (United States)

    This step-by-step guide can help small and mid-sized cities, particularly those that have limited population growth, areas of disinvestment, and/or a struggling economy, build a place-based economic development strategy.

  9. Foreign aid, governance quality, and economic growth in developing countries : foreign aid and growth

    OpenAIRE

    Biboh, Nkoumboh Henrietta

    2007-01-01

    Most poor developing countries, especially those with limited natural resources, low savings and investment levels, natural disaster stricken, need help from the affluent nations in order to meet some of their development objectives. Still, some that are rich in natural resources equally depend on some form of aid. Though most growth theories stress on investment as an important step to steady economic growth, they are mostly silent on the importance of aid as a component of in vestment and...

  10. Growth and Project Finance in the Least Developed Countries

    DEFF Research Database (Denmark)

    la Cour, Lisbeth F.; Müller, Jennifer

    2014-01-01

    data from the period 1994-2007. The results of our study suggest, that project finance has a significant positive effect on economic growth and therefore constitute an important source of financing in the selected set of countries. Additionally, the project sheds light on other factors of importance......This article examines the effects of project finance on economic growth in the least developed countries (LDC). Inspired by the neoclassical growth model we set up an econometric model to estimate the effects of project finance for a sample consisting of 38 of the least developed countries using...... for economic growth in LDCs. We find that a higher regulatory quality, lower government consumption and a higher level of education helps increase growth. The significance of these variables are, however, not as consistently robust as the results for project finance....

  11. Law, Economic Growth and Human Development: Evidence from Africa

    OpenAIRE

    Asongu Simplice

    2011-01-01

    This paper cuts adrift the mainstream approach to the legal-origins debate on the law-growth nexus by integrating both overall economic and human components in our understanding of how regulation quality and the rule of law lie at the heart of economic and inequality adjusted human developments. Findings summarily reveal that legal-origin does not explain economic growth and human development beyond the mechanisms of law. Our results support the current consensus that, English common-law coun...

  12. Sexual harassment.

    Science.gov (United States)

    Sbraga, T P; O'Donohue, W

    2000-01-01

    We review the current state of sexual harassment theory, research, treatment, and prevention. Definitional problems and implications are discussed. An examination of the epidemiology of sexual harassment is presented, highlighting correlates that include characteristics of the organizational environment, the perpetrator, and the recipient of unwanted sexual behavior. Normative responses to sexual harassment and consequences are discussed. Descriptions of the most prevalent models of sexual harassment are offered and the empirical evidence for them is briefly reviewed. From there, the effect of model development and evaluation on the prevention and treatment of sexual harassment is considered. We comment on the steps that would need to be taken to develop viable prevention and treatment programs. Suggestions for fruitful avenues of research and theory development are offered.

  13. Sexual Understanding and Development of Young People with Intellectual Disabilities: Mothers' Perspectives of Within-Family Context

    Science.gov (United States)

    Pownall, Jaycee D.; Jahoda, Andrew; Hastings, Richard; Kerr, Linda

    2011-01-01

    The sexual development of young people with intellectual disabilities is a marker of their transition to adulthood and affects their sense of well being and identity. Cognitive impairments and a socially marginalized position increase dependence on their families to assist with sexual matters. In this study, the authors adopted a novel…

  14. The development of sexual behavior in túngara frogs (Physalaemus pustulosus).

    Science.gov (United States)

    Baugh, Alexander T; Ryan, Michael J

    2010-02-01

    We examined the emergence of a critical component of sex, response to sexual signals-phonotaxis-in male and female túngara frogs (Physalaemus pustulosus). We determined the ontogenetic trajectories of phonotactic responses as animals developed from metamorphic froglets to reproductive adults. The results demonstrated that species-typical phonotaxis emerges quite early during postmetamorphic development, well before sexual maturity, suggesting that a developmentally early bias in the auditory system for species-typical signals might be a more general phenomenon than previously thought, and that the neural circuits responsible for processing and responding to conspecific advertisement signals in a species-typical manner might develop long before the coordinated behavior is demanded of the organism.

  15. Attenuation of cortisol across development for victims of sexual abuse

    OpenAIRE

    TRICKETT, PENELOPE K.; NOLL, JENNIE G.; SUSMAN, ELIZABETH J.; SHENK, CHAD E.; PUTNAM, FRANK W.

    2010-01-01

    Inconsistencies exist in literature examining hypothalamic–pituitary–adrenal (HPA) axis activity in children and adults who have experienced childhood abuse. Hence, the extent and manner to which childhood abuse may disrupt HPA axis development is largely unknown. To address these inconsistencies, the developmental course of nonstress cortisol in a long-term longitudinal study was assessed at six time points from childhood through adolescence and into young adulthood to determine whether chil...

  16. Financial development and economic growth in Ghana: Does the measure of financial development matter?

    Directory of Open Access Journals (Sweden)

    George Adu

    2013-07-01

    Full Text Available The aim of this paper is to investigate the long-run growth effects of financial development in Ghana. We find that the growth effect of financial development is sensitive to the choice of proxy. Both the credit to the private sector as ratios to GDP and total domestic credit are conducive for growth, while broad money stock to GDP ratio is not growth-inducing. The indexes created from principal component analysis confirmed the sensitivity of the effect to the choice of proxy. The findings here suggest that whether financial development is good or bad for growth depends on the indicator used to proxy for financial development.

  17. Normal Development of the Corpus Callosum and Evolution of Corpus Callosum Sexual Dimorphism in Infancy.

    Science.gov (United States)

    Chang, Chaw-Liang; Chiu, Nan-Chang; Yang, Yi-Chen; Ho, Che-Sheng; Hung, Kun-Long

    2018-04-01

    The aim of this study was to establish reference ranges for the corpus callosum in infancy and to clarify how sexual dimorphism evolves between the fetal stage and infancy. Normal sonograms from cerebral ultrasonographic examinations of 1- to 6-month-old healthy full-term infants were selected. The length and thickness of the corpus callosum were determined, and the effect of sex on these values was analyzed. Studies on corpus callosum sexual dimorphism were reviewed. In total, sonograms from 236 1- to 6-month-old infants (120 male and 116 female) were collected, and the typical values (5th-95th percentiles) of the corpus callosum were determined for each group. During the first 2 months, with and without brain size adjustment, the corpus callosum in female infants was significantly thicker than that in male infants (mean thickness ± SD: 1 month, male infant, 1.8 ± 0.3 mm; female infant, 2.1 ± 0.3 mm; P = .005; 2 months, male infant, 1.8 ± 0.2 mm; female infant, 2.0 ± 0.3 mm; P = .002). The corpus callosum thickness of male and female infants had no significant differences after 2 months of age. Sexual dimorphism was not detected in corpus callosum length. Our study provides reference data on typical corpus callosum development in infants. In the fetal period and early infancy, the corpus callosum in female infants is thicker than that in male infants. From 3 months onward, the corpus callosum sexual dimorphism becomes insignificant throughout childhood. The evolvement of corpus callosum sexual dimorphism suggests that maternal factors may influence brain development. © 2017 by the American Institute of Ultrasound in Medicine.

  18. Sexual differences in food intake, digestive tract size, and growth performance of the dab, Limanda limanda L.

    Science.gov (United States)

    Lozán, JoséLuis

    Sexual dimorphism in food intake, size of the digestive tract, hepatosomatic index and respiration were studied in dab from the southeastern North Sea both in the field and the laboratory, in order to explain observed differences in growth. The results show that the food intake of females is significantly greater than that of males. In a tank experiment 20-cm-long females consumed 73% more food than similar-sized males. Studies of deep-frozen samples caught during the main feeding period in August revealed that females contained 1.5 times as much food as males. Females appeared to have a significantly larger digestive tract than males determined on a dry-weight basis. During autumn and winter, females had heavier livers than males. No significant differences were found in the oxygen consumption rate.

  19. Beyond Cairo: sexual and reproductive rights of young people in the new development agenda.

    Science.gov (United States)

    Barroso, Carmen

    2014-01-01

    At the 1994 United Nations International Conference on Population and Development (ICPD), women's rights advocates fundamentally shifted the way the global development community views poverty, gender equality and reproductive rights. While the ICPD's call to action led to a marked improvement in reproductive health, more remains to be done to secure the sexual and reproductive rights and health of all, particularly for young people. As we approach the 20-year anniversary of Cairo, several global processes are happening concurrently that have implications for the future of the sexual and reproductive health and rights agenda, including the 20-year review of progress towards achieving the Cairo Programme of Action, the review of the Millennium Development Goals, and the open group discussions about the sustainable development goals and the new development agenda post-2015. There are five key areas of action where significant investment is needed moving forward to ensure young people's access and safeguard their rights: repeal outdated laws and create new policies that safeguard young people's health and rights; provide youth-friendly sexual and reproductive health services; guarantee young people's access to information and education; end gender discrimination and ensure government accountability.

  20. Developing a realistic sexual network model of chlamydia transmission in Britain

    Directory of Open Access Journals (Sweden)

    Mercer Catherine

    2006-01-01

    Full Text Available Abstract Background A national chlamydia screening programme is currently being rolled out in the UK and other countries. However, much of the epidemiology remains poorly understood. In this paper we present a stochastic, individual based, dynamic sexual network model of chlamydia transmission and its parameterisation. Mathematical models provide a theoretical framework for understanding the key epidemiological features of chlamydia: sexual behaviour, health care seeking and transmission dynamics. Results The model parameters were estimated either directly or by systematic fitting to a variety of appropriate data sources. The fitted model was representative of sexual behaviour, chlamydia epidemiology and health care use in England. We were able to recapture the observed age distribution of chlamydia prevalence. Conclusion Estimating parameters for models of sexual behaviour and transmission of chlamydia is complex. Most of the parameter values are highly correlated, highly variable and there is little empirical evidence to inform estimates. We used a novel approach to estimate the rate of active treatment seeking, by combining data sources, which improved the credibility of the model results. The model structure is flexible and is broadly applicable to other developed world settings and provides a practical tool for public health decision makers.

  1. Redefining Individual Growth and Development Indicators: Oral Language

    Science.gov (United States)

    Bradfield, Tracy A.; Besner, Amanda C.; Wackerle-Hollman, Alisha K.; Albano, Anthony D.; Rodriguez, Michael C.; McConnell, Scott R.

    2014-01-01

    Language skills developed during preschool contribute strongly to later reading and academic achievement. Effective preschool assessment and intervention should focus on core components of language development, specifically oral language skills. The Early Language and Literacy Individual Growth and Development Indicators (IGDIs) are a set of…

  2. Nuclear energy consumption and economic growth in nine developed countries

    International Nuclear Information System (INIS)

    Wolde-Rufael, Yemane; Menyah, Kojo

    2010-01-01

    This article attempts to test the causal relationship between nuclear energy consumption and real GDP for nine developed countries for the period 1971-2005 by including capital and labour as additional variables. Using a modified version of the Granger causality test developed by Toda and Yamamoto (1995), we found a unidirectional causality running from nuclear energy consumption to economic growth in Japan, Netherlands and Switzerland; the opposite uni-directional causality running from economic growth to nuclear energy consumption in Canada and Sweden; and a bi-directional causality running between economic growth and nuclear energy consumption in France, Spain, the United Kingdom and the United States. In Spain, the United Kingdom and the USA, increases in nuclear energy consumption caused increases in economic growth implying that conservation measures taken that reduce nuclear energy consumption may negatively affect economic growth. In France, Japan, Netherlands and Switzerland increases in nuclear energy consumption caused decreases in economic growth, suggesting that energy conservation measure taken that reduce nuclear energy consumption may help to mitigate the adverse effects of nuclear energy consumption on economic growth. In Canada and Sweden energy conservation measures affecting nuclear energy consumption may not harm economic growth.

  3. Using GIS for Developing Sustainable Urban Growth Case Kyrenia Region

    Science.gov (United States)

    Kara, C.; Akçit, N.

    2018-03-01

    It is critical to develop urban layers for analysis sustainable urban development possibilities within planning process. Kyrenia Region has many physical, environmental or economic issues that may danger the growth possibilities in sustainable manner. From this point, this study uses different spatial layers such as slope, distance to roads, distance to central zone, vegetation, soil productivity, environmental protection zones, distance to open/green space, distance to education for supporting sustainable urban growth policies and define suitable areas for urban development within this perspective. The study tries to convert sustainable urban growth policies such as; compact growth, environmental protection, equal accessibility to basic services; into spatial layers and establish proper framework for multi criteria evaluation in Kyrenia Region within using geographical information systems. It shows suitability values for Kyrenia region and constraints zones at final section. It clearly presents the suitable areas for the sustainable urbanization and also unsuitable or risky areas for reducing the possible disasters and may happen in the future.

  4. Financial sector development & firm growth in BRICS countries

    Directory of Open Access Journals (Sweden)

    Shame Mugova

    2017-11-01

    Full Text Available The development of an economy’s financial sector facilitates improved access to capital. This study focuses on firm growth in terms of how much assets it controls and BRICS is chosen as the empirical medium of investigation. The impact financial sector development on firm growth amongst 3353 listed firms in BRICS countries is investigated using a GMM estimation technique. Firm’s investment in assets increases the organizational resources and productive capacity needed to achieve growth in the market. Financial sector development improves access to capital and firms with higher access to external finance pursue growth opportunities using debt. Financial sector development helps firms to adjust their capital structures quickly thereby minimizing the costs of staying off target. The speed of adjustment of firms towards their target capital structure facilitates financing of firm growth. The study found that listed firms in Brazil, Russia India, China and South Africa have a target total liabilities-to-total assets ratio and financial sector development helps firms to partially adjust towards target levels and pursue growth opportunities

  5. Risk factors and outcomes of chronic sexual harassment during the transition to college: Examination of a two-part growth mixture model

    OpenAIRE

    McGinley, Meredith; Wolff, Jennifer M.; Rospenda, Kathleen M.; Liu, Li; Richman, Judith A.

    2016-01-01

    A two-part latent growth mixture model was implemented in order to examine heterogeneity in the growth of sexual harassment (SH) victimization in college and university students, and the extent to which SH class membership explains substance use and mental health outcomes for certain groups of students. Demographic risk factors, mental health, and substance use were examined as they related to chronically experienced SH victimization. Incoming freshmen students (N = 2855; 58% female; 54% Whit...

  6. Fgfr1 signalling in the development of a sexually selected trait in vertebrates, the sword of swordtail fish

    Directory of Open Access Journals (Sweden)

    Meyer Axel

    2008-10-01

    Full Text Available Abstract Background One of Darwin's chosen examples for his idea of sexual selection through female choice was the "sword", a colourful extension of the caudal fin of male swordtails of the genus Xiphophorus. Platyfish, also members of the genus Xiphophorus, are thought to have arisen from within the swordtails, but have secondarily lost the ability to develop a sword. The sustained increase of testosterone during sexual maturation initiates sword development in male swordtails. Addition of testosterone also induces sword-like fin extensions in some platyfish species, suggesting that the genetic interactions required for sword development may be dormant, rather than lost, within platyfish. Despite considerable interest in the evolution of the sword from a behavioural or evolutionary point of view, little is known about the developmental changes that resulted in the gain and secondary loss of the sword. Up-regulation of msxC had been shown to characterize the development of both swords and the gonopodium, a modified anal fin that serves as an intromittent organ, and prompted investigations of the regulatory mechanisms that control msxC and sword growth. Results By comparing both development and regeneration of caudal fins in swordtails and platyfish, we show that fgfr1 is strongly up-regulated in developing and regenerating sword and gonopodial rays. Characterization of the fin overgrowth mutant brushtail in a platyfish background confirmed that fin regeneration rates are correlated with the expression levels of fgfr1 and msxC. Moreover, brushtail re-awakens the dormant mechanisms of sword development in platyfish and activates fgfr1/msxC-signalling. Although both genes are co-expressed in scleroblasts, expression of msxC in the distal blastema may be independent of fgfr1. Known regulators of Fgf-signalling in teleost fins, fgf20a and fgf24, are transiently expressed only during regeneration and thus not likely to be required in developing swords

  7. Report of the international consensus development conference on female sexual dysfunction: definitions and classifications

    NARCIS (Netherlands)

    Basson, R.; Berman, J.; Burnett, A.; Derogatis, L.; Ferguson, D.; Fourcroy, J.; Goldstein, I.; Graziottin, A.; Heiman, J.; Laan, E.; Leiblum, S.; Padma-Nathan, H.; Rosen, R.; Segraves, K.; Segraves, R. T.; Shabsigh, R.; Sipski, M.; Wagner, G.; Whipple, B.

    2000-01-01

    PURPOSE: Female sexual dysfunction is highly prevalent but not well defined or understood. We evaluated and revised existing definitions and classifications of female sexual dysfunction. MATERIALS AND METHODS: An interdisciplinary consensus conference panel consisting of 19 experts in female sexual

  8. The influence of certain environmental factors on the sexual development and reproductive ability of Karakul sheep

    International Nuclear Information System (INIS)

    Faure, A.S.

    1986-01-01

    An investigation conducted on the influence of season of birth on sexual development, reproduction and luteinizing hormone of karakul sheep is described. The influence of season of birth on testosterone and semen properties of rams as well as nutrition and exogenous oestrogen of ewes are discussed. A radioimmunology technique was used for the determination of testosterone concentration of karakul rams. A Radioimmunology technique was also used for the determination of the plasma concentration of oestrogen and progesterone of ewe lambs. Results obtained, provided sufficient evidence that the Karakul sheep can reproduce successfully early in life which is desirable to enhance reproduction. It also emphasised the importance of optimal nutrition to promote sexual development and reproduction

  9. People with Intellectual Disabilities Talk About Sexuality: Implications for the Development of Sex Education

    OpenAIRE

    Schaafsma, D.; Kok, G.; Stoffelen, J. M. T.; Curfs, L. M. G.

    2016-01-01

    Existing sex education programmes have failed in involving people with intellectual disabilities in the development of these programmes. Not involving the target population decreases the likelihood that the sex education programme will be effective. This study was conducted to assess the perspectives of people with intellectual disabilities on several sexuality-related topics. Semi-structured interviews were held with 20 people with intellectual disabilities covering topics such as: sex educa...

  10. Metabolic Profiling Reveals Effects of Age, Sexual Development and Neutering in Plasma of Young Male Cats.

    Directory of Open Access Journals (Sweden)

    David Allaway

    Full Text Available Neutering is a significant risk factor for obesity in cats. The mechanisms that promote neuter-associated weight gain are not well understood but following neutering, acute changes in energy expenditure and energy consumption have been observed. Metabolic profiling (GC-MS and UHPLC-MS-MS was used in a longitudinal study to identify changes associated with age, sexual development and neutering in male cats fed a nutritionally-complete dry diet to maintain an ideal body condition score. At eight time points, between 19 and 52 weeks of age, fasted blood samples were taken from kittens neutered at either 19 weeks of age (Early Neuter (EN, n = 8 or at 31 weeks of age (Conventional Neuter (CN, n = 7. Univariate and multivariate analyses were used to compare plasma metabolites (n = 370 from EN and CN cats. Age was the primary driver of variance in the plasma metabolome, including a developmental change independent of neuter group between 19 and 21 weeks in lysolipids and fatty acid amides. Changes associated with sexual development and its subsequent loss were also observed, with differences at some time points observed between EN and CN cats for 45 metabolites (FDR p<0.05. Pathway Enrichment Analysis also identified significant effects in 20 pathways, dominated by amino acid, sterol and fatty acid metabolism. Most changes were interpretable within the context of male sexual development, and changed following neutering in the CN group. Felinine metabolism in CN cats was the most significantly altered pathway, increasing during sexual development and decreasing acutely following neutering. Felinine is a testosterone-regulated, felid-specific glutathione derivative secreted in urine. Alterations in tryptophan, histidine and tocopherol metabolism observed in peripubertal cats may be to support physiological functions of glutathione following diversion of S-amino acids for urinary felinine secretion.

  11. Puberty and adolescent sexuality.

    Science.gov (United States)

    Fortenberry, J Dennis

    2013-07-01

    This article is part of a Special Issue "Puberty and Adolescence". Sexuality emerges as a major developmental element of puberty and the adolescent years that follow. However, connecting the sexuality that emerges with puberty and elements of adult sexuality is difficult because much adolescent sexuality research addresses the transition to partnered sexual behaviors (primarily coitus) and consequences such as unplanned pregnancy and sexually transmitted infections. This review proposes a framework of an expanded understanding of puberty and adolescent sexuality from the perspective of four hallmarks of adult sexuality: sexual desire; sexual arousal; sexual behaviors; and, sexual function. This approach thus addresses important gaps in understanding of the ontogeny of sex and the continuum of sexuality development from adolescence through the adult lifespan. Copyright © 2013 Elsevier Inc. All rights reserved.

  12. Becoming a sexual being: The ‘elephant in the room’ of adolescent brain development

    Directory of Open Access Journals (Sweden)

    Ahna Ballonoff Suleiman

    2017-06-01

    Full Text Available The onset of adolescence is a time of profound changes in motivation, cognition, behavior, and social relationships. Existing neurodevelopmental models have integrated our current understanding of adolescent brain development; however, there has been surprisingly little focus on the importance of adolescence as a sensitive period for romantic and sexual development. As young people enter adolescence, one of their primary tasks is to gain knowledge and experience that will allow them to take on the social roles of adults, including engaging in romantic and sexual relationships. By reviewing the relevant human and animal neurodevelopmental literature, this paper highlights how we should move beyond thinking of puberty as simply a set of somatic changes that are critical for physical reproductive maturation. Rather, puberty also involves a set of neurobiological changes that are critical for the social, emotional, and cognitive maturation necessary for reproductive success. The primary goal of this paper is to broaden the research base and dialogue about adolescent romantic and sexual development, in hopes of advancing understanding of sex and romance as important developmental dimensions of health and well-being in adolescence.

  13. Becoming a sexual being: The 'elephant in the room' of adolescent brain development.

    Science.gov (United States)

    Suleiman, Ahna Ballonoff; Galván, Adriana; Harden, K Paige; Dahl, Ronald E

    2017-06-01

    The onset of adolescence is a time of profound changes in motivation, cognition, behavior, and social relationships. Existing neurodevelopmental models have integrated our current understanding of adolescent brain development; however, there has been surprisingly little focus on the importance of adolescence as a sensitive period for romantic and sexual development. As young people enter adolescence, one of their primary tasks is to gain knowledge and experience that will allow them to take on the social roles of adults, including engaging in romantic and sexual relationships. By reviewing the relevant human and animal neurodevelopmental literature, this paper highlights how we should move beyond thinking of puberty as simply a set of somatic changes that are critical for physical reproductive maturation. Rather, puberty also involves a set of neurobiological changes that are critical for the social, emotional, and cognitive maturation necessary for reproductive success. The primary goal of this paper is to broaden the research base and dialogue about adolescent romantic and sexual development, in hopes of advancing understanding of sex and romance as important developmental dimensions of health and well-being in adolescence. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  14. Sexual and reproductive health and rights in the post-2015 development agenda.

    Science.gov (United States)

    Sen, Gita

    2014-01-01

    Women's health is currently shaped by the confluence of two important policy trends - the evolution of health system reform policies and from the early 1990s onwards, a strong articulation of a human rights-based approach to health that has emphasised laws and policies to advance gender equality and sexual and reproductive health and rights (SRHR). The drive for sexual and reproductive rights represents an inclusive trend towards human rights to health that goes beyond the right to health services, directing attention to girls' and women's rights to bodily autonomy, integrity and choice in relation to sexuality and reproduction. Such an expanded concept of the right to health is essential if laws, policies and programmes are to respect, protect and fulfil the health of girls and women. However, this expanded understanding has been ghettoised from the more mainstream debates on the right to health and was only partially included in the Millennium Development Goals. The paper argues in favour of a twofold approach in placing SRHR effectively in the context of the post-2015 development agenda: first, firmly ground it in an inclusive approach to the right to health; and second, drawing on two decades of national-level implementation, propose a forward-looking agenda focusing on quality, equality and accountability in policies and in programmes. This can build on good practice while addressing critical challenges central to the development framework itself.

  15. Changes in lipid composition during sexual development of the malaria parasite Plasmodium falciparum.

    Science.gov (United States)

    Tran, Phuong N; Brown, Simon H J; Rug, Melanie; Ridgway, Melanie C; Mitchell, Todd W; Maier, Alexander G

    2016-02-06

    The development of differentiated sexual stages (gametocytes) within human red blood cells is essential for the propagation of the malaria parasite, since only mature gametocytes will survive in the mosquito's midgut. Hence gametocytogenesis is a pre-requisite for transmission of the disease. Physiological changes involved in sexual differentiation are still enigmatic. In particular the lipid metabolism-despite being central to cellular regulation and development-is not well explored. Here the lipid profiles of red blood cells infected with the five different sexual stages of Plasmodium falciparum were analysed by mass spectrometry and compared to those from uninfected and asexual trophozoite infected erythrocytes. Fundamental differences between erythrocytes infected with the different parasite stages were revealed. In mature gametocytes many lipids that decrease in the trophozoite and early gametocyte infected red blood cells are regained. In particular, regulators of membrane fluidity, cholesterol and sphingomyelin, increased significantly during gametocyte maturation. Neutral lipids (serving mainly as caloriometric reserves) increased from 3 % of total lipids in uninfected to 27 % in stage V gametocyte infected red blood cells. The major membrane lipid class (phospholipids) decreased during gametocyte development. The lipid profiles of infected erythrocytes are characteristic for the particular parasite life cycle and maturity stages of gametocytes. The obtained lipid profiles are crucial in revealing the lipid metabolism of malaria parasites and identifying targets to interfere with this deadly disease.

  16. Metabolic Profiling Reveals Effects of Age, Sexual Development and Neutering in Plasma of Young Male Cats.

    Science.gov (United States)

    Allaway, David; Gilham, Matthew S; Colyer, Alison; Jönsson, Thomas J; Swanson, Kelly S; Morris, Penelope J

    2016-01-01

    Neutering is a significant risk factor for obesity in cats. The mechanisms that promote neuter-associated weight gain are not well understood but following neutering, acute changes in energy expenditure and energy consumption have been observed. Metabolic profiling (GC-MS and UHPLC-MS-MS) was used in a longitudinal study to identify changes associated with age, sexual development and neutering in male cats fed a nutritionally-complete dry diet to maintain an ideal body condition score. At eight time points, between 19 and 52 weeks of age, fasted blood samples were taken from kittens neutered at either 19 weeks of age (Early Neuter (EN), n = 8) or at 31 weeks of age (Conventional Neuter (CN), n = 7). Univariate and multivariate analyses were used to compare plasma metabolites (n = 370) from EN and CN cats. Age was the primary driver of variance in the plasma metabolome, including a developmental change independent of neuter group between 19 and 21 weeks in lysolipids and fatty acid amides. Changes associated with sexual development and its subsequent loss were also observed, with differences at some time points observed between EN and CN cats for 45 metabolites (FDR pcats was the most significantly altered pathway, increasing during sexual development and decreasing acutely following neutering. Felinine is a testosterone-regulated, felid-specific glutathione derivative secreted in urine. Alterations in tryptophan, histidine and tocopherol metabolism observed in peripubertal cats may be to support physiological functions of glutathione following diversion of S-amino acids for urinary felinine secretion.

  17. Growth and development and their environmental and biological determinants.

    Science.gov (United States)

    da Rocha Neves, Kelly; de Souza Morais, Rosane Luzia; Teixeira, Romero Alves; Pinto, Priscilla Avelino Ferreira

    2016-01-01

    To investigate child growth, cognitive/language development, and their environmental and biological determinants. This was a cross-sectional, predictive correlation study with all 92 children aged 24-36 months who attended the municipal early childhood education network in a town in the Vale do Jequitinhonha region, in 2011. The socioeconomic profile was determined using the questionnaire of the Associação Brasileira de Empresas de Pesquisa. The socio-demographicand maternal and child health profiles were created through a self-prepared questionnaire. The height-for-age indicator was selected to represent growth. Cognitive/language development was assessed through the Bayley Scale of Infant and Toddler Development. The quality of educational environments was assessed by Infant/Toddler Environment Scale; the home environment was assessed by the Home Observation for Measurement of the Environment. The neighborhood quality was determined by a self-prepared questionnaire. A multivariate linear regression analysis was performed. Families were predominantly from socioeconomic class D, with low parental education. The prevalence of stunted growth was 14.1%; cognitive and language development were below average at 28.6% and 28.3%, respectively. Educational institutions were classified as inadequate, and 69.6% of homes were classified as presenting a risk for development. Factors such as access to parks and pharmacies and perceived security received the worst score regarding neighborhood environment. Biological variables showed a greater association with growth and environmental variables with development. The results showed a high prevalence of stunting and below-average results for cognitive/language development among the participating children. Both environmental and biological factors were related to growth and development. However, biological variables showed a greater association with growth, whereas environmental variables were associated with development

  18. Insulin-like growth factors in embryonic and fetal growth and skeletal development (Review).

    Science.gov (United States)

    Agrogiannis, Georgios D; Sifakis, Stavros; Patsouris, Efstratios S; Konstantinidou, Anastasia E

    2014-08-01

    The insulin-like growth factors (IGF)-I and -II have a predominant role in fetal growth and development. IGFs are involved in the proliferation, differentiation and apoptosis of fetal cells in vitro and the IGF serum concentration has been shown to be closely correlated with fetal growth and length. IGF transcripts and peptides have been detected in almost every fetal tissue from as early in development as pre‑implantation to the final maturation stage. Furthermore, IGFs have been demonstrated to be involved in limb morphogenesis. However, although ablation of Igf genes in mice resulted in growth retardation and delay in skeletal maturation, no impact on outgrowth and patterning of embryonic limbs was observed. Additionally, various molecular defects in the Igf1 and Igf1r genes in humans have been associated with severe intrauterine growth retardation and impaired skeletal maturation, but not with truncated limbs or severe skeletal dysplasia. The conflicting data between in vitro and in vivo observations with regard to bone morphogenesis suggests that IGFs may not be the sole trophic factors involved in fetal skeletal growth and that redundant mechanisms may exist in chondro- and osteogenesis. Further investigation is required in order to elucidate the functions of IGFs in skeletal development.

  19. Effect of young maternal age and skeletal growth on placental growth and development.

    Science.gov (United States)

    Hayward, C E; Greenwood, S L; Sibley, C P; Baker, P N; Jones, R L

    2011-12-01

    Teenagers are susceptible to delivering small-for-gestational-age infants. Previous studies implicate continued skeletal growth as a contributory factor, and impaired placental development was the primary cause of fetal growth restriction in growing adolescent sheep. The aims of this study were to examine the impact of young maternal age and growth on placental development. Placentas were collected from 31 teenagers, of which 12 were growing and 17 non-growing based on knee height measurements. An adult control group (n = 12) was included. Placental weight and morphometric measurements of villous, syncytiotrophoblast, fibrin and vessel areas, as well as indices of proliferation and apoptosis, were analysed in relation to maternal growth and age. Growing teenagers had a higher birthweight:placental weight ratio than non-growing teenagers (p adult and teenage pregnancies. Maternal smoking, a potential confounding factor, did not exert a major influence on the placental parameters examined, except for a stimulatory effect on placental proliferation (p development, and is consistent with our recent observations that maternal growth was not detrimental to fetal growth. Copyright © 2011 Elsevier Ltd. All rights reserved.

  20. Exposure to monocrotophos pesticide during sexual development causes the feminization/demasculinization of the reproductive traits and a reduction in the reproductive success of male guppies (Poecilia reticulata).

    Science.gov (United States)

    Tian, Hua; Li, Yun; Wang, Wei; Wu, Peng; Ru, Shaoguo

    2012-09-01

    Monocrotophos is a highly toxic organophosphorus pesticide that has been confirmed to be an endocrine-disrupting chemical. To evaluate the influence of this pollutant on the reproductive system of male fish, we studied the sex steroid levels, reproductive traits, sex ratio, and reproductive success in male guppies (Poecilia reticulata) exposed to 40% monocrotophos pesticide at the nominal concentrations of 0.01, 0.10, and 1.00 mg/L for 90 days from birth to adulthood in a semi-static exposure system. Radioimmunoassay and western blot analyses demonstrated that the long-term exposure to monocrotophos pesticide during the sexual development of male guppies caused a significant increase in 17β-estradiol levels and consequently induced vitellogenin synthesis, suggesting the feminization of the males. Monocrotophos pesticide also caused a significant decrease in testosterone levels, which consequently inhibited testis growth and reduced the sperm count and the area and intensity of their sexually attractive orange spots, which collectively indicated the significant demasculinization of the male sexual characteristics. Furthermore, these changes in the sexual characteristics at the cellular and organ levels translated into ecologically important effects on the reproductive success at the individual level, as measured by a decrease in offspring production and survival rate. The present study provides the first evidence that monocrotophos pesticide can cause severe reproductive abnormalities in fish due to its endocrine-disrupting action. Copyright © 2012 Elsevier Inc. All rights reserved.

  1. Growth And Oil Futures Prices In Developing Countries

    OpenAIRE

    Salah Abosedra; Sajal Ghosh

    2011-01-01

    This paper examines cointegration and causality between oil prices and economic growth for the oil importing developing countries of Turkey, India, Pakistan, The Philippines and Korea. The study finds the absence of cointegrating relationship between oil prices and economic activity but the existence of unidirectional short-run causality running from oil prices to economic growths for The Philippines and Pakistan. Unidirectional causality is also found to exist from six and nine month futures...

  2. Developing a financial inclusion index and inclusive growth in India

    OpenAIRE

    Susanta Kumar SETHY

    2016-01-01

    Financial inclusion is one of the systems through which Inclusive Growth can be achieved in developing countries like India where large sections are unable or hopeless to contribute in the financial system. An inclusive financial system mobilizes more resources for productive purposes leading to higher economic growth, better opportunities and reduction of poverty. This study, proposed an Index of financial inclusion – a multidimensional measure. The Financial Inclusion Index c...

  3. Growth, economic development and structural transition in small vulnerable states

    OpenAIRE

    Read, Robert

    2001-01-01

    This paper reviews the critical theoretical and policy issues relating to growth, economic development and structural transition in small states. The paper discusses alternative perspectives on small size and highlights the salient characteristics which give rise to their economic sub-optimality. The theoretical and empirical relationship between size and growth is reviewed, including recent inferences relating to structural transition and comparative advantage in small states. This discussio...

  4. Human Capital, Population Growth and Economic Development: Beyond Correlations

    OpenAIRE

    Rosenzweig, Mark R.

    1987-01-01

    Empirical evidence on three assertions commonly-made by population policy advocates about the relationships among population growth, human capital formation and economic development is discussed and evaluated in the light of economic-biological models of household behavior and of its relevance to population policy. The three assertions are that (a) population growth and human capital investments jointly reflect and respond to changes in the economic environment, (b) larger families directly i...

  5. Conventional Development Versus Managed Growth: The Costs of Sprawl

    Science.gov (United States)

    Burchell, Robert W.; Mukherji, Sahan

    2003-01-01

    Objectives. We examined the effects of sprawl, or conventional development, versus managed (or “smart”) growth on land and infrastructure consumption as well as on real estate development and public service costs in the United States. Methods. Mathematical impact models were used to produce US estimates of differences in resources consumed according to each growth scenario over the period 2000–2025. Results. Sprawl produces a 21% increase in amount of undeveloped land converted to developed land (2.4 million acres) and approximately a 10% increase in local road lane-miles (188 300). Furthermore, sprawl causes about 10% more annual public service (fiscal) deficits ($4.2 billion) and 8% higher housing occupancy costs ($13 000 per dwelling unit). Conclusions. Managed growth can save significant amounts of human and natural resources with limited effects on traditional development procedures. PMID:12948976

  6. VALIDATION REPORT (PHASE 2) FOR THE FISH SEXUAL DEVELOPMENT TEST FOR THE DETECTION OF ENDOCRINE ACTIVE SUBSTANCES

    DEFF Research Database (Denmark)

    Holbech, Henrik; Kinnberg, Karin Lund; Petersen, Gitte

    This document presents the validation report (phase 2) of the Fish Sexual Development Test (FSDT). The Fish Sexual Development Test (FSDT) covers a life-stage where sexual development is particularly sensitive to perturbation caused by endocrine active chemicals. The chemical exposure lasts...... Guideline on the fish sexual development test to the Working Group of the National Coordinators of the Test Guidelines Programme (WNT). The project was included on the Test Guidelines workplan in 2003, and extensive validation of the test method was carried out until 2009. Two validation studies were...... for about 60 days, at the end of which endpoints of ecological relevance like the sex ratio of the exposed fish is calculated and the biomarker endpoint vitellogenin is measured in individual animals. In 2003, Denmark, on behalf of the European Nordic countries, proposed a new project o develop a Test...

  7. Functional genomics of root growth and development in Arabidopsis.

    Science.gov (United States)

    Iyer-Pascuzzi, Anjali; Simpson, June; Herrera-Estrella, Luis; Benfey, Philip N

    2009-04-01

    Roots are vital for the uptake of water and nutrients, and for anchorage in the soil. They are highly plastic, able to adapt developmentally and physiologically to changing environmental conditions. Understanding the molecular mechanisms behind this growth and development requires knowledge of root transcriptomics, proteomics, and metabolomics. Genomics approaches, including the recent publication of a root expression map, root proteome, and environment-specific root expression studies, are uncovering complex transcriptional and post-transcriptional networks underlying root development. The challenge is in further capitalizing on the information in these datasets to understand the fundamental principles of root growth and development. In this review, we highlight progress researchers have made toward this goal.

  8. Testosterone-induced adult neurosphere growth is mediated by sexually-dimorphic aromatase expression

    Directory of Open Access Journals (Sweden)

    Mark Ian Ransome

    2015-07-01

    Full Text Available We derived adult neural stem/progenitor cells (NSPCs from the sub-ventricular zone of male and female mice to examine direct responses to principal sex hormones. In the presence of epidermal growth factor (EGF and fibroblast growth factor-2 (FGF2 NSPCs of both sexes expressed nestin and sox2 and could be maintained as neurospheres without addition of any sex hormones. The reverse was not observed; neither testosterone (T, 17β-oestradiol (E2 nor progesterone (P4 was able to support neurosphere growth in the absence of EGF and FGF2. 10nM T, E2 or P4 induced nestin(+ cell proliferation within 20 minutes and enhanced neurosphere growth over 7 days irrespective of sex, which was abolished by Erk inhibition with 20M U0126. Maintaining neurospheres with each sex hormone did not affect subsequent neuronal differentiation. However, 10nM T, E2 or P4 added during differentiation increased III tubulin(+ neuron production with E2 being more potent compared to T and P4 in both sexes. Androgen receptor (AR inhibition with 20M flutamide but not aromatase inhibition with 10M letrozole reduced basal and T-induced neurosphere growth in females, while only concurrent inhibition of AR and aromatase produced the same effect in males. This sex-specific effect was supported by higher aromatase expression in male neurospheres compared to females measured by Western blot and green fluorescent protein reporter. 10M menadione induced oxidative stress, impaired neurosphere growth and up-regulated aromatase expression in both sexes. However, under oxidative stress letrozole significantly exacerbated impaired neurosphere growth in males only. While both E2 and T could prevent oxidative stress-induced growth reduction in both sexes, the effects of T were dependent on innate aromatase activity. We show for the first time that intrinsic androgen and estrogen signalling may impact the capacity of NSPCs to produce neural progenitors under pathological conditions of

  9. The impact of globalization on the industrial growth of developing ...

    African Journals Online (AJOL)

    This paper is an attempt to investigate the impact of globalization on the industrial growth of developing economies with special reference to Nigeria. Globalization has facilitated the increased flow of ideas; people, goods and services across national frontiers. Some developing countries as a result of globalization have ...

  10. Foreign direct investment, financial development and economic growth

    NARCIS (Netherlands)

    Hermes, C.L.M.; Lensink, B.W.

    2003-01-01

    This article argues that the development of the financial system of the recipient country is an important precondition for FDI to have a positive impact on economic growth. A more developed financial system positively contributes to the process of technological diffusion associated with FDI. The

  11. Population growth, human development, and deforestation in biodiversity hotspots.

    Science.gov (United States)

    Jha, S; Bawa, K S

    2006-06-01

    Human population and development activities affect the rate of deforestation in biodiversity hotspots. We quantified the effect of human population growth and development on rates of deforestation and analyzed the relationship between these causal factors in the 1980s and 1990s. We compared the averages of population growth, human development index (HDI, which measures income, health, and education), and deforestation rate and computed correlations among these variables for countries that contain biodiversity hotspots. When population growth was high and HDI was low there was a high rate of deforestation, but when HDI was high, rate of deforestation was low, despite high population growth. The correlation among variables was significant for the 1990s but not for the 1980s. The relationship between population growth and HDI had a regional pattern that reflected the historical process of development. Based on the changes in HDI and deforestation rate over time, we identified two drivers of deforestation: policy choice and human-development constraints. Policy choices that disregard conservation may cause the loss of forests even in countries that are relatively developed. Lack of development in other countries, on the other hand, may increase the pressure on forests to meet the basic needs of the human population. Deforestation resulting from policy choices may be easier to fix than deforestation arising from human development constraints. To prevent deforestation in the countries that have such constraints, transfer of material and intellectual resources from developed countries may be needed. Popular interest in sustainable development in developed countries can facilitate the transfer of these resources.

  12. Relative growth and sexual maturity of the freshwater shrimp Palaemon pandaliformis (Crustacea, Palaemonidae in northeastern of Brazil (Canavieiras, Bahia

    Directory of Open Access Journals (Sweden)

    Lucas R. P. Paschoal

    2013-03-01

    Full Text Available This study comprises the description of relative growth and sexual maturity of a population of Palaemon pandaliformis Stimpson, 1871 in Salsa River (Northeastern Brazil. Samples were collected monthly between September 2009 and August 2010. Females were larger, heavier, and showed a greater allometric coefficient (b than male specimens. Only carapace length vs. pleura length in females presented a significant difference in the relative growth pattern, indicating a puberty moult. This relationship is strictly correlated to reproduction and its success rate in female shrimps. Estimated carapace length in 50% of mature females (CL50 was 4.53 mm. It was not possible to compare obtained CL50 results due to a lack of studies on this species. Comparison was based on the size of the smallest captured ovigerous female (3.81 CL mm, which is within the scope of recorded size for estuaries located in higher latitudes. This study reveals the lack of research on this genre in freshwater environments on a national and global scale.

  13. The Impact of Stigma and Social Support on Development of Post-traumatic Growth Among Persons Living with HIV.

    Science.gov (United States)

    Kamen, Charles; Vorasarun, Chaniga; Canning, Ty; Kienitz, Eliza; Weiss, Carolyn; Flores, Sergio; Etter, Darryl; Lee, Susanne; Gore-Felton, Cheryl

    2016-06-01

    Given high rates of trauma in people living with HIV (PLH) and the health benefits of posttraumatic growth (PTG), understanding how to foster PTG in PLH exposed to trauma could be of interest to clinical psychologists working with this population. The current study examined factors theoretically related to development of PTG in PLH, namely HIV-related stigma, disclosure of HIV status, and emotional support. A sample of 334 HIV-positive adults answered a battery of self-report questionnaires. HIV-related stigma, disclosure to sexual partners, and emotional support were significant predictors of PTG: stigma was associated with lower PTG, whereas disclosure and emotional support were associated with higher PTG. Disclosure and emotional support remained significantly associated with PTG in the model including demographic factors and stigma. These findings highlight the need for development of interventions that can aid PLH in disclosing their HIV status to sexual partners and increasing available social support.

  14. Plant Growth Research for Food Production: Development and Testing of Expandable Tuber Growth Module

    Science.gov (United States)

    Cordova, Brennan A.

    2017-01-01

    Controlled and reliable growth of a variety of vegetable crops is an important capability for manned deep space exploration systems for providing nutritional supplementation and psychological benefits to crew members. Because current systems have been limited to leafy vegetables that require minimal root space, a major goal for these systems is to increase their ability to grow new types of crops, including tuber plants and root vegetables that require a large root space. An expandable root zone module and housing was developed to integrate this capability into the Veggie growth system. The expandable module uses a waterproof, gas-permeable bag with a structure that allows for root space to increase vertically throughout the growth cycle to accommodate for expanding tuber growth, while minimizing the required media mass. Daikon radishes were chosen as an ideal tuber crop for their subterraneous tuber size and rapid growth cycle, and investigations were done to study expanding superabsorbent hydrogels as a potential growth media. These studies showed improved water retention, but restricted oxygen availability to roots with pure gel media. It was determined that these hydrogels could be integrated in lower proportions into standard soil to achieve media expansion and water retention desired. Using the constructed module prototype and ideal gel and soil media mixture, Daikon radishes were grown in the system to test the capability and success of the system through a full growth cycle.

  15. Evidence on Economic Growth and Financial Development in Montenegro

    Directory of Open Access Journals (Sweden)

    Milena Lipovina-Bozovic

    2016-12-01

    Full Text Available Macroeconomic development must be supported by a stable and efficient financial system. There are many different measures of financial development that are suggested when the relationship between growth and financial system is analyzed. In this paper we will identify the most important indicators of the financial development in Montenegro. Due to the fact that in the last decade Montenegrin financial market has been developing, we want to see if that fact had an influence on the economic growth, as well as if there is significant positive relationship between the growth and financial development. The intention of this article is to use principal components in order to examine correlation among indicators and find means or main components. This technique has the advantage of giving more general measures of financial development rather than individual variables for bank or stock market development. It could be concluded that it is difficult to identify the specific components of the financial system most associated with the economic growth.

  16. The immunocompetence handicap hypothesis in two sexually dimorphic pinniped species - is there a sex difference in immunity during early development?

    NARCIS (Netherlands)

    Hall, AJ; Englehard, GH; Brasseur, SMJM; Vecchione, A; Burton, HR; Reijnders, PJH

    2003-01-01

    The 'immunocompetence handicap hypothesis' predicts that highly sexually dimorphic and polygynous species will exhibit sex differences in immunity. We tested this hypothesis in southern elephant and grey seals during their early development by measuring the following parameters: leucocyte counts,

  17. The immunocompetence handicap hypothesis in two sexually dimorphic pinniped species - there a sex difference in immunity during early development?

    NARCIS (Netherlands)

    Hall, A.J.; Engelhard, G.H.; Brasseur, S.M.J.M.; Vecchione, A.; Burton, H.R.; Reijnders, P.J.H.

    2003-01-01

    The 'immunocompetence handicap hypothesis' predicts that highly sexually dimorphic and polygynous species will exhibit sex differences in immunity. We tested this hypothesis in southern elephant and grey seals during their early development by measuring the following parameters: leucocyte counts,

  18. Relative growth, sexual dimorphism and morphometric maturity of Trichodactylus fluviatilis (Decapoda: Brachyura: Trichodactylidae from Santa Terezinha, Bahia, Brazil

    Directory of Open Access Journals (Sweden)

    Tiago Rozário da Silva

    2014-02-01

    Full Text Available Freshwater crabs are important elements in the aquatic biota of brooks, rivers, lakes and ponds, from both ecological and the socio-economic aspects. Trichodactylidae comprises 51 endemic species from the Neotropical region. Among all the species of this family, Trichodactylus fluviatilis Latreille, 1828 has the widest geographic distribution throughout Brazil. Despite that, there are few published contributions on the biology of this species. The present study investigated the following aspects of T. fluviatilis: relative growth, mean size at onset of morphometric maturity, sexual dimorphism, laterality and heterochely. Specimens were collected monthly from September 2010 through August 2011, from the Velha Eugênia Brook, municipality of Santa Teresinha, State of Bahia. Carapace width (CW, carapace length (CL, major cheliped length (MaCL and minor cheliped length (MiCL, major cheliped height (MaCH and minor cheliped height (MiCH, and width of the fifth abdominal segment (5AB were measured to evaluate the presence of sexual dimorphism; the major difference between the sexes was in the CW vs. 5AB ratio. Heterochely was observed in males and females,with the right cheliped larger than the left in 89% of males and 81% of females. Crab size at the onset of morphometric maturity (= puberty molt was estimated based on the ratio between CL, cheliped dimensions, 5AB and CW (independent variable. Females were larger than males when they reached morphometric maturity in all studied relations. We recommend the use of chelipeds and abdominal width relationships to estimate the size at the morphometric maturity in males and females, respectively.

  19. How online sexual health services could work; generating theory to support development.

    Science.gov (United States)

    Baraitser, Paula; Syred, Jonathan; Spencer-Hughes, Vicki; Howroyd, Chris; Free, Caroline; Holdsworth, Gillian

    2015-12-05

    Online sexual health services are an emerging area of service delivery. Theory of change critically analyses programmes by specifying planned inputs and articulating the causal pathways that link these to anticipated outcomes. It acknowledges the changing and contested nature of these relationships. We developed two versions of a theory of change for an online sexual health service. The first articulated the theory presented in the original programme proposal and the second documented its development in the early stages of implementation through interviews with key programme stakeholders. The programme proposal described an autonomous and empowered user completing a sexual health check using a more convenient, accessible and discreet online service and a shift from clinic based to online care. The stakeholder interviews confirmed this and described new and more complex patterns of service use as the online service creates opportunities for providers to contact users outside of the traditional clinic visit and users move between online and clinic based care. They described new types of user/provider relationships which we categorised as: those influenced by an online retail culture; those influenced by health promotion outreach and surveillance and those acknowledging the need for supported access. This analysis of stakeholder views on the likely the impacts of online sexual health services suggests three areas for further thinking and research. 1. Co-development of clinic and online services to support complex patterns of service use. 2. Developing access to online services for those who could use them with support. 3. Understanding user experience of sexual health services as increasing user autonomy and choice in some situations; creating exclusion and a need for support in others and intrusiveness and a lack of control in still others. This work has influenced the evaluation of this programme which will focus on; mapping patterns of use to understand how users

  20. Alguns aspectos observados no desenvolvimento de crianças vítimas de abuso sexual Children victims of sexual abuse: some aspects observed in their development

    Directory of Open Access Journals (Sweden)

    Mayte Raya Amazarray

    1998-01-01

    Full Text Available O abuso sexual de crianças é um dos tipos de maus-tratos mais freqüentes, apresentando implicações médicas, legais e psicossociais. Essa revisão da literatura aponta para algumas conseqüências do abuso sexual infantil, com o objetivo de entender o seu impacto no desenvolvimento da criança. Os efeitos prejudiciais do abuso sexual, a reação negativa da família e o despreparo dos profissionais constituem um potencial gerador de danos psicológicos para a criança. Devido a esses fatores, as crianças vitimizadas encontram-se em situação de risco. Portanto, faz-se necessária uma capacitação dos profissionais que trabalham com essas crianças e com suas famílias, de modo que se possa obter a versão real dos casos, bem como conduzir uma intervenção adequada.Child sexual abuse is one of the most frequent form of maltreatment, which has medical, legal, and psychosocial implications. This review of the literature points out to some consequences of child sexual abuse, aiming to the understanding of its impact on the child’s development. The adverse effects of sexual abuse, the negative reaction of the family, and the unpreparedness of professionals represent potencial source of psychological damage to the child. Due to these factors, the children who are victimized are at risk. For this reason, it is necessary to professionalize the people who work with these children and their families to allow them to do proper diagnosis and to carry out proper interventions.

  1. The Internet's Multiple Roles in Facilitating the Sexual Orientation Identity Development of Gay and Bisexual Male Adolescents.

    Science.gov (United States)

    Harper, Gary W; Serrano, Pedro A; Bruce, Douglas; Bauermeister, Jose A

    2016-09-01

    One emerging avenue for the exploration of adolescents' sexual orientation identity development is the Internet, since it allows for varying degrees of anonymity and exploration. The purpose of this phenomenological study was to examine the role of the Internet in facilitating the sexual orientation identity development process of gay and bisexual male adolescents. Qualitative interviews were conducted with an ethnically diverse sample of 63 gay/bisexual male adolescents (ages 15-23). Participants reported using a range of Internet applications as they explored and came to accept their sexual orientation identity, with the intended purpose and degree of anonymity desired determining which applications were used. Youth reported that the Internet provided a range of functions with regard to the exploration and acceptance of their sexual orientation identity, including (1) increasing self-awareness of sexual orientation identity, (2) learning about gay/bisexual community life, (3) communicating with other gay/bisexual people, (4) meeting other gay/bisexual people, (5) finding comfort and acceptance with sexual orientation, and (6) facilitating the coming out process. Future research and practice may explore the Internet as a platform for promoting the healthy development of gay and bisexual male adolescents by providing a developmentally and culturally appropriate venue for the exploration and subsequent commitment to an integrated sexual orientation identity. © The Author(s) 2015.

  2. Problematic Sexual Behaviour in a Secure Psychiatric Setting: Challenges and Developing Solutions

    Science.gov (United States)

    Hughes, Gareth V.; Hebb, Jo

    2005-01-01

    Sexually abusive behaviours are common in a forensic psychiatric population, both before admission and while hospitalized. A survey of our medium security facility found that 41% of patients had a history of sexually abusive behaviours, ranging from convictions for sexual assault through to current episodes of sexual harassment. Most forensic…

  3. Metropolitan migration and population growth in selected developing countries.

    Science.gov (United States)

    1983-01-01

    The purpose of this article is to estimate the components of metropolitan population growth in selected developing countries during 1960-1970 period. The study examines population growth in 26 cities: 5 are in Africa, 8 in Asia, and 13 in Latin America, using data from national census publications. These cities in general are the political capitals of their countries, but some additional large cities were selected in Brazil, Mexico, and South Africa. All cities, at the beginning of the 1960-1970 decade had over 500,000 population; Accra, the only exception, reached this population level during the 1960s. Some cities had over 4 million residents in 1970. Net migration contributed about 37% to total metropolitan population growth; the remainder of the growth is attributable to natural increase. Migration has a much stronger impact on metropolitan growth than suggested by the above figure: 1) Several metropolitan areas, for various reasons, are unlikely to receive many migrants; without those cities, the share of metropolitan growth from net migration is 44%. 2) Estimates of the natural increase of migrants after their arrival in the metropolitan areas, when added to migration itself, changes the total contribution of migration to 49% in some metropolitan areas. 3) Even where net migration contributes a smaller proportion to metropolitan growth than natural increase, the rates of net migration are generally high and should be viewed in the context of rapid metropolitan population growth from natural increase alone. Finally, the paper also compares the components of metropolitan growth with the components of growth in the remaining urban areas. The results show that the metropolitan areas, in general, grow faster than the remaining urban areas, and that this more rapid growth is mostly due to a higher rate of net migration. Given the significance of migration for metropolitan growth, further investigations of the effects of these migration streams, particularly with

  4. A reference growth curve for nutritional experiments in zebrafish (Danio rerio) and changes in whole body proteome during development.

    Science.gov (United States)

    Gómez-Requeni, P; Conceição, L E C; Olderbakk Jordal, A-E; Rønnestad, I

    2010-12-01

    Zebrafish is one of the most used vertebrate model organisms in molecular and developmental biology, recently gaining popularity also in medical research. However, very little work has been done to assess zebrafish as a model species in nutritional studies in aquaculture in order to utilize the methodological toolbox that this species represents. As a starting point to acquire some baseline data for further nutritional studies, growth of a population of zebrafish was followed for 15 weeks. Furthermore, whole body proteome was screened during development by means of bi-dimensional gel electrophoresis and mass spectrometry. Fish were reared under best practice laboratory conditions from hatching until 103 days post-fertilization (dpf) and regularly fed ad libitum with Artemia nauplii from 12 dpf. A growth burst occurred within 9-51 dpf, reaching a plateau after 65 dpf. Fork length and body weight were significantly lower in males than in females from 58 dpf onwards. Proteomics analysis showed 28 spot proteins differently expressed through development and according to sex. Of these proteins, 20 were successfully identified revealing proteins involved in energy production, muscle development, eye lens differentiation, and sexual maturation. In summary, zebrafish exhibited a rapid growth until approximately 50 dpf, when most individuals started to allocate part of the dietary energy intake for sexual maturation. However, proteomic analysis revealed that some individuals reached sexual maturity earlier and already from 30 dpf onwards. Thus, in order to design nutritional studies with zebrafish fed Artemia nauplii, it is recommended to select a period between 20 and 40 dpf, when fish allocate most of the ingested energy for non-reproductive growth purposes.

  5. A review of risk and protective factors for adolescent sexual and reproductive health in developing countries: an update.

    Science.gov (United States)

    Mmari, Kristin; Sabherwal, Simran

    2013-11-01

    To conduct a literature review of studies that examined risk and protective factors related to adolescent sexual and reproductive health in developing countries. A literature search was conducted using multiple databases, including PubMed, PsycINFO, Scopus, JSTOR, and the Interagency Youth Working Group. Review criteria included publications that: were conducted in a low- or middle-income country; had a sample size of at least 100 young people aged 10-24 years, and used multivariate analysis. All studies that were identified were also conducted between 1990 and 2010, a 20-year time frame. The literature search and initial review yielded a total of 244 studies that met the criteria and analyzed risk and protective factors related to the following outcomes: sexual initiation, number of sexual partners, condom use, contraceptive use, pregnancy and early childbearing, human immunodeficiency virus, sexually transmitted infections, and sexual coercion. Most studies that were conducted on adolescent sexual and reproductive health in developing countries were largely focused in Sub-Saharan African contexts, and primarily examined factors related to sexual initiation and condom use. Most factors that examined an adolescent sexual and reproductive health outcome were also focused on the individual level, although an increasing number of studies within the past 10 years have focused on family-level factors. Few studies examined factors at the community or neighborhood level, which, to date, has largely been ignored in developing country contexts. The review not only summarizes what is currently known in terms of risk and protective factors that relate to adolescent sexual and reproductive health in developing countries, but also highlights the gaps. Implications for future research are discussed. Copyright © 2013 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  6. Research & development and growth: A Bayesian model averaging analysis

    Czech Academy of Sciences Publication Activity Database

    Horváth, Roman

    2011-01-01

    Roč. 28, č. 6 (2011), s. 2669-2673 ISSN 0264-9993. [Society for Non-linear Dynamics and Econometrics Annual Conferencen. Washington DC, 16.03.2011-18.03.2011] R&D Projects: GA ČR GA402/09/0965 Institutional research plan: CEZ:AV0Z10750506 Keywords : Research and development * Growth * Bayesian model averaging Subject RIV: AH - Economics Impact factor: 0.701, year: 2011 http://library.utia.cas.cz/separaty/2011/E/horvath-research & development and growth a bayesian model averaging analysis.pdf

  7. Growth and development of cassava (Manihot esculenta crantz)

    Energy Technology Data Exchange (ETDEWEB)

    Ramanujam, T.; Muraleedharan Nair, G.; Indira, P.

    1984-07-01

    The growth and development of twelve cassava genotypes were studied under the shade in a coconut garden. Internodal elongation, thin leaves and absence of branching were the most significant morphological changes noticed under shade. Cross section of leaves grown under shade showed poor starch deposition in vascular region. Most of the photosynthates of shade grown cassava were utilized for shoot growth affecting tuber development significantly. The cultivars H 165 and CI 590 recorded higher yield under shade when compared to other cultivars. Wider spacings of cassava in coconut garden resulted in higher tuber yield. 9 references.

  8. Eye growth and myopia development: Unifying theory and Matlab model.

    Science.gov (United States)

    Hung, George K; Mahadas, Kausalendra; Mohammad, Faisal

    2016-03-01

    The aim of this article is to present an updated unifying theory of the mechanisms underlying eye growth and myopia development. A series of model simulation programs were developed to illustrate the mechanism of eye growth regulation and myopia development. Two fundamental processes are presumed to govern the relationship between physiological optics and eye growth: genetically pre-programmed signaling and blur feedback. Cornea/lens is considered to have only a genetically pre-programmed component, whereas eye growth is considered to have both a genetically pre-programmed and a blur feedback component. Moreover, based on the Incremental Retinal-Defocus Theory (IRDT), the rate of change of blur size provides the direction for blur-driven regulation. The various factors affecting eye growth are shown in 5 simulations: (1 - unregulated eye growth): blur feedback is rendered ineffective, as in the case of form deprivation, so there is only genetically pre-programmed eye growth, generally resulting in myopia; (2 - regulated eye growth): blur feedback regulation demonstrates the emmetropization process, with abnormally excessive or reduced eye growth leading to myopia and hyperopia, respectively; (3 - repeated near-far viewing): simulation of large-to-small change in blur size as seen in the accommodative stimulus/response function, and via IRDT as well as nearwork-induced transient myopia (NITM), leading to the development of myopia; (4 - neurochemical bulk flow and diffusion): release of dopamine from the inner plexiform layer of the retina, and the subsequent diffusion and relay of neurochemical cascade show that a decrease in dopamine results in a reduction of proteoglycan synthesis rate, which leads to myopia; (5 - Simulink model): model of genetically pre-programmed signaling and blur feedback components that allows for different input functions to simulate experimental manipulations that result in hyperopia, emmetropia, and myopia. These model simulation programs

  9. Sexual dimorphism and identification of single nucleotide polymorphism of growth hormone gene in muscovy duck

    Directory of Open Access Journals (Sweden)

    I. Ismoyowati

    2017-08-01

    Full Text Available This research was aimed to investigate the different growth and to identify growth hormone gene polymorphism in Muscovy ducks. Two hundred Muscovy day-old ducks consisting of white-plumed male and female duck, black and white-plumed male and female ducks. Body weight was recorded weekly and the obtained data were subject to T test. Primer design used the Custal X Program based on a database from the GeneBank Cairina moschata GH gene, partial cds (AB158762. Primer base sequence of GH gene was forward/Sequence: 5’-CTGGGGTTGTTTAGCTTGGA-3’ and reverse/Sequence: 5’-TAAACCTTCCCTGGCACAAC-3’. The DNA sequences were aligned by using the BioEdit version 7.7 for identification of the single nucleotide polymorphism. The result showed that male Muscovy duck produced higher an average body weight gain and more relative growth than those of females. The highest body weight gain was at three weeks old, and then it started to decrease at four weeks old. The sequencing PCR product obtained nucleotide polymorphism. AA genotype was observed at 136 t of black female Muscovy duck, CC in black and white male Muscovy duck, and white female Muscovy duck. Conclusively, a body weight gain of 3-week-old male Muscovy ducks was higher than that of females and GH gene polymorphism was observed in Muscovy ducks.

  10. [Penis growth and development in children and adolescents: a study based on GAMLSS].

    Science.gov (United States)

    Yi, Qing-Jie; Zeng, Yan; Zeng, Qing; Wang, Yi-Nan; Xiong, Feng

    2017-08-01

    To investigate penis development in children and adolescents aged 0-16 years, and to plot the percentile curve for penis development in different age groups. A total of 3 024 normal male neonates, children, and adolescents aged 0-16 years in Chongqing, China were selected by simple random sampling and stratified cluster sampling. The length and diameter of the penis were measured for all subjects. A descriptive statistical analysis was used to investigate the data characteristics of the penis, and the GAMLSS fitting model was used to plot the percentile curves of P 3 , P 10 , P 25 , P 50 , P 75 , P 90 , and P97 and obtain percentile reference values. The length and diameter of the penis grew rapidly before the age of 1 year, grew relatively slowly from 1 to 11 years old, and entered a rapid growth period from 11 years old. The length of the penis was positively correlated with its diameter (r=0.961, Pgrowth and development of penis length is consistent with that of penis diameter in male children and adolescents in Chongqing, and 0-1 year and 11-16 years are rapid growth periods of penis length and diameter. The percentile curve of penis length and diameter in children and adolescents aged 0-16 years in Chongqing which has been established will provide a reference for further studies on sexual development in children and adolescents.

  11. A Call to Action: Developing and Strengthening New Strategies to Promote Adolescent Sexual Health

    Directory of Open Access Journals (Sweden)

    Martha J. Decker

    2015-10-01

    Full Text Available Through considerable efforts and investments of resources, adolescent pregnancy and birth rates in the United States have decreased significantly over the past two decades. Nonetheless, large disparities persist for many populations of youth. Reducing unintended adolescent pregnancies is considered a “winnable public health battle,” but one that will require innovative thinking and continued persistence. This paper reviews the recent research literature and innovative programmatic efforts to identify six promising strategies that address the challenge of adolescent pregnancy in new ways. These strategies aim to: (1 understand and address the complexity of adolescent lives; (2 expand the provision of quality sexual health education; (3 engage youth through technology and media; (4 increase access to contraceptives and other sexual health services; (5 create tailored interventions for populations with special needs; and (6 create a supportive policy environment. By building upon lessons learned from past efforts, we can move the field toward the development, strengthening, and promotion of future strategies that enhance the sexual well-being of all adolescents.

  12. The role of population on economic growth and development: evidence from developing countries

    OpenAIRE

    Atanda, Akinwande A.; Aminu, Salaudeen B.; Alimi, Olorunfemi Y.

    2012-01-01

    The precise relationship between population growth and per capita income has been inconclusive in the literature and the nexus has been found not clearly explain the determinants of rapid population growth in developing countries that lacks fertility control and management framework. This forms the rationale for this study to access the trend of factors that influence rapid population growth in developing countries between 1980 and 2010. This paper examined the comparative trend review of pop...

  13. Perceived "out of control" sexual behavior in a cohort of young adults from the Dunedin Multidisciplinary Health and Development Study.

    Science.gov (United States)

    Skegg, Keren; Nada-Raja, Shyamala; Dickson, Nigel; Paul, Charlotte

    2010-08-01

    Out of control sexual behavior, also known as compulsive sexual behavior or sexual addiction, has not been studied in a representative sample of the general population. At age 32 years, 940 (93%) of 1,015 members of the birth cohort of the Dunedin Multidisciplinary Health and Development Study responded to a series of questions about sexual behavior, administered by computer. We enquired about sexual fantasies, urges or behavior that participants regarded as out of control during the previous year, and defined such experiences as out of control sexual experiences (OCSE). Nearly 13% of men and 7% of women reported OCSE in the past year. Women who reported such experiences were more likely than other women to have reported (elsewhere in the interview) having had high numbers of opposite sex partners, concurrent sexual relationships, or sex with a partner met on the internet, as well as a higher likelihood of same-sex attraction or behavior. Among men reporting OCSE, there was an association with having paid for heterosexual sex and with same-sex attraction and behavior. Few believed that OCSE had interfered with their lives (3.8% of all men and 1.7% of all women in the cohort). Only 0.8% of men and 0.6% of women reported that their actual sexual behavior had interfered with their lives. OCSE were also analyzed in relation to certain personality traits and to childhood sexual abuse (CSA). Some evidence of a link with impulsivity (women only) and negative affectivity was found. CSA was associated with OCSE among men. In conclusion, this population-based study has provided the first empirical estimations of the occurrence of OCSE and its relationship to a range of sexual behaviors in a representative sample.

  14. Gay and bisexual identity development among female-to-male transsexuals in North America: emergence of a transgender sexuality.

    Science.gov (United States)

    Bockting, Walter; Benner, Autumn; Coleman, Eli

    2009-10-01

    We studied a North American sample of female-to-male (FtM) transsexuals sexually attracted to men, aiming to understand their identity and sexuality in the context of a culture of transgender empowerment. Sex-reassigned FtM transsexuals, 18 years or older and attracted to men, were recruited via an FtM community conference and listserv. Participants (N = 25) responded to open-ended questions about identity development, sexual behavior, and social support. Data were analyzed by content analysis. Scores for sexual identity, self esteem, sexual functioning, and psychological adjustment were compared to those of a comparison group (N = 76 nontransgender gay and bisexual men). Of the 25 FtMs, 15 (60%) identified as gay, 8 (32%) as bisexual, and 2 (8%) as queer. All were comfortable with their gender identity and sexual orientation. The FtM group was more bisexual than the nontransgender gay and bisexual controls. No significant group differences were found in self esteem, sexual satisfaction, or psychological adjustment. For some FtMs, sexual attractions and experiences with men affirmed their gender identity; for others, self-acceptance of a transgender identity facilitated actualization of their attractions toward men. Most were "out" as transgender among friends and family, but not on the job or within the gay community. Disclosure and acceptance of their homosexuality was limited. The sexual identity of gay and bisexual FtMs appears to mirror the developmental process for nontransgender homosexual men and women in several ways; however, participants also had experiences unique to being both transgender and gay/bisexual. This signals the emergence of a transgender sexuality.

  15. Rethinking Sexual Citizenship.

    Science.gov (United States)

    Richardson, Diane

    2017-04-01

    Over the last two decades sexuality has emerged as a key theme in debates about citizenship, leading to the development of the concept of sexual citizenship. This article reviews this literature and identifies four main areas of critical framing: work that contests the significance of sexuality to citizenship; critiques that focus on the possibilities and limitations of mobilising the language of citizenship in sexual politics; analyses of sexual citizenship in relation to nationalisms and border making; and literature that critically examines western constructions of sexuality and sexual politics underpinning understandings of sexual citizenship. In order to progress the field theoretically, the article seeks to extend critiques of sexual citizenship focusing on two key aspects of its construction: the sexual citizen-subject and spaces of sexual citizenship. It argues for a critical rethink that encompasses a de-centring of a 'western-centric' focus in order to advance understandings of how sexual citizenship operates both in the Global North and South.

  16. Economic Growth of a Rapidly Developing Economy: Theoretical Formulation

    Directory of Open Access Journals (Sweden)

    Oleg Sergeyevich Sukharev

    2016-06-01

    Full Text Available The subject matter of the article is the description of economic growth. Modern economy is characterized by a high rate of changes. These changes are the limiting parameters of modern development, which requires a modification of the basic models of growth, the substantiation of the expediency and necessity of a rapid development strategy. In a simple mathematical form, the statement of the problem of economic growth in the “green economy” is examined, in which the costs of environmental measures are not considered a priori as hampering economic development (as it is common for a number of modern neoclassical and neo-Keynesian growth models. The methodological basis of the article are the econometric approach and modelling method. The article has a theoretical character. The main hypothesis supposes that the rapid development strategy cannot make an adequate development strategy under certain conditions, but may be acceptable in other its specific conditions. In this sense, the important growth conditions are the availability of resources, the effectiveness of institutions and the current economic structure, the technological effectiveness of economy, as well as the conditions of technological development (“green economy” and the path of such development. In the article, on the theoretical level of analysis, the substantiation of the adequacy of the rapid development strategy for an economic system is given, whose goal is to achieve the standard of living of the countryleader. Based on the assumptions introduced, the period for which the rapid development strategy might be implemented and the economic lag of the country might be reduced from the country-leader is determined. The conditions that ensure the impact of innovations on the rate of economic development are summarized. The introduced range of dependencies and relations can be useful for the elaboration of the theory of innovation development and for the formation of a new

  17. Compulsory sexuality.

    Science.gov (United States)

    Emens, Elizabeth F

    2014-02-01

    Asexuality is an emerging identity category that challenges the common assumption that everyone is defined by some type of sexual attraction. Asexuals--those who report feeling no sexual attraction to others--constitute one percent of the population, according to one prominent study. In recent years, some individuals have begun to identify as asexual and to connect around their experiences interacting with a sexual society. Asexuality has also become a protected classification under the antidiscrimination law of one state and several localities, but legal scholarship has thus far neglected the subject. This Article introduces asexuality to the legal literature as a category of analysis, an object of empirical study, and a phenomenon of medical science. It then offers a close examination of the growing community of self-identified asexuals. Asexual identity has revealing intersections with the more familiar categories of gender, sexual orientation, and disability, and inspires new models for understanding sexuality. Thinking about asexuality also sheds light on our legal system. Ours is arguably a sexual law, predicated on the assumption that sex is important. This Article uses asexuality to develop a framework for identifying the ways that law privileges sexuality. Across various fields, these interactions include legal requirements of sexual activity, special carve-outs to shield sexuality from law, legal protections from others' sexuality, and legal protections for sexual identity. Applying this framework, the Article traces several ways that our sexual law burdens, and occasionally benefits, asexuals. This Article concludes by closely examining asexuality's prospects for broader inclusion into federal, state, and local antidiscrimination laws.

  18. Importance of peers and dating in the development of romantic relationships and sexual activity of young adults with cerebral palsy.

    Science.gov (United States)

    Wiegerink, Diana J H G; Roebroeck, Marij E; van der Slot, Wilma Ma; Stam, Henk J; Cohen-Kettenis, Peggy T

    2010-06-01

    The aim of this study was to describe the peer group activities, romantic relationships, and sexual activity and their interrelations of young adults with cerebral palsy (CP). A cross-sectional study was performed in 87 participants (51 males, 36 females; mean age 20 y 4 mo, SD 1 y 3 mo range age 18-22 y) without cognitive disabilities. Ninety-four per cent had spastic CP and 49% unilateral CP, while 78% were classified at Gross Motor Function Classification System level I and 84% at Manual Ability Classification System level I. Peer group activities, dating, romantic relationships, and sexual activity were assessed with an interview and questionnaire. Associations were analysed using logistic regression analyses. The study cohort reported having friends and participating in activities with peers; 71% had experience of dating, 23% had a current romantic relationship, and 38% had experience of intercourse. Young adults with CP had less experience in romantic and sexual relationships than an age-appropriate Dutch reference population. Peer group activities and dating favoured development of romantic relationships and sexual activity. Older age was associated with greater sexual activity. Motor functioning, education level, and gender did not correlate with romantic relationships or sexual activity. Being involved in peer group activities and creating a context to arrange dates seems relevant for young adults with CP to develop romantic relationships and sexual activity.

  19. Transforming growth factor-beta1 null mutation causes infertility in male mice associated with testosterone deficiency and sexual dysfunction.

    Science.gov (United States)

    Ingman, Wendy V; Robertson, Sarah A

    2007-08-01

    TGFbeta1 is a multifunctional cytokine implicated in gonad and secondary sex organ development, steroidogenesis, and spermatogenesis. To determine the physiological requirement for TGFbeta1 in male reproduction, Tgfb1 null mutant mice on a Prkdc(scid) immunodeficient background were studied. TGFbeta1-deficient males did not deposit sperm or induce pseudopregnancy in females, despite an intact reproductive tract with morphologically normal penis, seminal vesicles, and testes. Serum and intratesticular testosterone and serum androstenedione were severely diminished in TGFbeta1-deficient males. Testosterone deficiency was secondary to disrupted pituitary gonadotropin secretion because serum LH and to a lesser extent serum FSH were reduced, and exogenous LH replacement with human chorionic gonadotropin (hCG) induced serum testosterone to control levels. In the majority of TGFbeta1-deficient males, spermatogenesis was normal and sperm were developmentally competent as assessed by in vitro fertilization. Analysis of sexual behavior revealed that although TGFbeta1 null males showed avid interest in females and engaged in mounting activity, intromission was infrequent and brief, and ejaculation was not attained. Administration of testosterone to adult males, even after neonatal androgenization, was ineffective in restoring sexual function; however, erectile reflexes and ejaculation could be induced by electrical stimulation. These studies demonstrate the profound effect of genetic deficiency in TGFbeta1 on male fertility, implicating this cytokine in essential roles in the hypothalamic-pituitary-gonadal axis and in testosterone-independent regulation of mating competence.

  20. Life Insurance Contribution, Insurance Development and Economic Growth in China

    Directory of Open Access Journals (Sweden)

    Wang Ying

    2017-07-01

    Full Text Available Under L-type economy, remodelling the growth power in the medium and long term is essential. The insurance industry during the 13th Five-year Plan period has been given a heavy expectation on promoting economic quality and upgrading economic efficiency, so it will try to accelerate its innovation and development process which serves national needs, market demand and people's requirements. Referring to the previous researches of Solow and Zhang and measuring Capital Stock and Total Factor Productivity independently, the paper analyses the inherent correlation between insurance (including life insurance and non-life insurance and economic growth, reveals the contribution law of the insurance development in economic growth in the short and long term from both economic scale and quality respectively. It also shows enlightenments on policy decision for insurance industry, thus helps economic stability under the downturn periods.

  1. Growth of a Species, an Association, a Science: 80 Years of Growth and Development Research

    Science.gov (United States)

    Sherwood, Richard J.; Duren, Dana L.

    2014-01-01

    Physical anthropological research was codified in the United States with the creation of the American Association of Physical Anthropology (AAPA) in 1929. That same year, a study began in yellow springs, Ohio, with a goal of identifying “what makes people different.” The approach used to answer that question was to study the growth and development of Homo sapiens. The resulting study, the Fels Longitudinal Study, is currently the longest continuous study of human growth and development in the world. Although the AAPA and the Fels Longitudinal Study have existed as separate entities for more than 80 years now, it is not surprising, given the relationship between anatomical and developmental research, there has been considerable overlap between the two. As the field of physical anthropology has blossomed to include subdisciplines such as forensics, genetics, primatology, as well as sophisticated statistical methodologies, the importance of growth and development research has escalated. Although current Fels Longitudinal Study research is largely directed at biomedical questions, virtually all findings are relevant to physical anthropology, providing insights into basic biological processes and life history parameters. Some key milestones from the early years of the AAPA and the Fels Longitudinal Study are highlighted here that address growth and development research in physical anthropology. These are still held as fundamental concepts that underscore the importance of this line of inquiry, not only across the subdisciplines of physical anthropology, but also among anthropological, biological, and biomedical inquiries. PMID:23283658

  2. Evaluating the Need for Sex Education in Developing Countries: Sexual Behaviour, Knowledge of Preventing Sexually Transmitted Infections/HIV and Unplanned Pregnancy

    Science.gov (United States)

    Singh, Susheela; Bankole, Akinrinola; Woog, Vanessa

    2005-01-01

    Young people's need for sex education is evidenced by their typically early initiation of sexual activity, the often involuntary context within which they have sexual intercourse, high-risk sexual behaviours and the inadequate levels of knowledge of means of protecting their sexual health. The earliness of initiation of sexual intercourse has…

  3. Energy intake functions and energy budgets of ectotherms and endotherms derived from their ontogenetic growth in body mass and timing of sexual maturation.

    Science.gov (United States)

    Werner, Jan; Sfakianakis, Nikolaos; Rendall, Alan D; Griebeler, Eva Maria

    2018-05-07

    Ectothermic and endothermic vertebrates differ not only in their source of body temperature (environment vs. metabolism), but also in growth patterns, in timing of sexual maturation within life, and energy intake functions. Here, we present a mathematical model applicable to ectothermic and endothermic vertebrates. It is designed to test whether differences in the timing of sexual maturation within an animal's life (age at which sexual maturity is reached vs. longevity) together with its ontogenetic gain in body mass (growth curve) can predict the energy intake throughout the animal's life (food intake curve) and can explain differences in energy partitioning (between growth, reproduction, heat production and maintenance, with the latter subsuming any other additional task requiring energy) between ectothermic and endothermic vertebrates. With our model we calculated from the growth curves and ages at which species reached sexual maturity energy intake functions and energy partitioning for five ectothermic and seven endothermic vertebrate species. We show that our model produces energy intake patterns and distributions as observed in ectothermic and endothermic species. Our results comply consistently with some empirical studies that in endothermic species, like birds and mammals, energy is used for heat production instead of growth, and with a hypothesis on the evolution of endothermy in amniotes published by us before. Our model offers an explanation on known differences in absolute energy intake between ectothermic fish and reptiles and endothermic birds and mammals. From a mathematical perspective, the model comes in two equivalent formulations, a differential and an integral one. It is derived from a discrete level approach, and it is shown to be well-posed and to attain a unique solution for (almost) every parameter set. Numerically, the integral formulation of the model is considered as an inverse problem with unknown parameters that are estimated using a

  4. Financial development and corporate growth in the EU single market

    Czech Academy of Sciences Publication Activity Database

    Bena, J.; Jurajda, Štěpán

    2011-01-01

    Roč. 78, č. 311 (2011), s. 401-428 ISSN 0013-0427 R&D Projects: GA MŠk LC542 Institutional research plan: CEZ:AV0Z70850503 Keywords : financial development * corporate growth * access to financial markets Subject RIV: AH - Economics Impact factor: 1.152, year: 2011

  5. Development of a minimal growth medium for Lactobacillus plantarum

    NARCIS (Netherlands)

    Wegkamp, H.B.A.; Teusink, B.; Vos, de W.M.; Smid, E.J.

    2010-01-01

    Aim: A medium with minimal requirements for the growth of Lactobacillus plantarum WCFS was developed. The composition of the minimal medium was compared to a genome-scale metabolic model of L. plantarum. Methods and Results: By repetitive single omission experiments, two minimal media were

  6. Financial development and growth in direct firm-level comparisons

    Czech Academy of Sciences Publication Activity Database

    Bena, Jan; Jurajda, Š.

    -, č. 317 (2007), s. 1-40 ISSN 1211-3298 R&D Projects: GA MŠk LC542 Institutional research plan: CEZ:AV0Z70850503 Keywords : financial development * corporate growth * access to financial market s Subject RIV: AH - Economics http://www.cerge-ei.cz/pdf/wp/Wp317.pdf

  7. Financial development and growth in direct firm-level comparisons

    Czech Academy of Sciences Publication Activity Database

    Bena, J.; Jurajda, Štěpán

    -, č. 6395 (2007), s. 1-26 ISSN 0265-8003 R&D Projects: GA MŠk LC542 Institutional research plan: CEZ:MSM0021620846 Keywords : access to financial market s * corporate growth * financial development Subject RIV: AH - Economics http://www.cepr.org/pubs/new-dps/dplist.asp?dpno=6395

  8. Financial development and growth in direct firm-level comparisons

    Czech Academy of Sciences Publication Activity Database

    Bena, Jan; Jurajda, Š.

    -, č. 6395 (2007), s. 1-26 ISSN 0265-8003 R&D Projects: GA MŠk LC542 Institutional research plan: CEZ:AV0Z70850503 Keywords : access to financial market s * corporate growth * financial development Subject RIV: AH - Economics http://www.cepr.org/pubs/new-dps/dplist.asp?dpno=6395

  9. Financial development and growth in direct firm-level comparisons

    Czech Academy of Sciences Publication Activity Database

    Bena, J.; Jurajda, Štěpán

    -, Č. 317 (2007), s. 1-40 ISSN 1211-3298 R&D Projects: GA MŠk LC542 Institutional research plan: CEZ:MSM0021620846 Keywords : financial development * corporate growth * access to financial market s Subject RIV: AH - Economics http://www.cerge-ei.cz/pdf/wp/Wp317.pdf

  10. Economic Growth and Development in the Undergraduate Curriculum

    Science.gov (United States)

    Acemoglu, Daron

    2013-01-01

    A central theme of this article is that economics instructors should spend more time teaching about economic growth and development at the undergraduate level because the topic is of interest to students, is less abstract than other macroeconomic topics, and is the focus of exciting research in economics. Facts and data can be presented to…

  11. Foreign direct investment and economic growth in developing ...

    African Journals Online (AJOL)

    It has been widely claimed that foreign direct investment (FDI) stimulates economic growth. In this study, an attempt is made to verify this for ten selected Sub-Saharan African (SSA) countries using data spanning from 2008 to 2013 obtained from world development indicators. Preliminary analysis conducted indicates that ...

  12. Attracting Foreign Direct Investment for Growth and Development in ...

    African Journals Online (AJOL)

    How can sub-Saharan Africa attract more FDI for its growth and development efforts? What policy options are available to these countries? What strategic alternatives can sub-Saharan countries adopt to increase FDI inflows? What role can multilateral and bilateral organisations play in this effort? This paper will address ...

  13. The Contribution of food plants to the growth, development and ...

    African Journals Online (AJOL)

    The Contribution of food plants to the growth, development and fecundity of Zonocerus variegatus (L) ... African Journal of Biotechnology ... The performance of the variegated grasshopper, Zonocerus variegatus (L) fed on different food plants namely cassava (Manihot esculenta), pawpaw (Carica papaya) and acalypha ...

  14. Soil science, population growth and food production: some historical developments

    NARCIS (Netherlands)

    Hartemink, A.E.

    2007-01-01

    The world¿s population has doubled since 1960. Currently, the developing world accounts for about 95% of the population growth with Africa as the world¿s fastest growing continent. The growing population has many implications but most of all it requires an increase in agricultural production to meet

  15. road sector development and economic growth in ethiopia1

    African Journals Online (AJOL)

    Eyerusalem

    Ibrahim Worku: Road sector development and economic growth in Ethiopia. 134 identified, i.e., the excluded instruments are "relevant", meaning correlated with the endogenous regressors. Under the null that the equation is underidentified, the statistic is distributed as chi-squared with degrees of freedom (L1-K1+1).

  16. Models of economic growth and development in the context of ...

    African Journals Online (AJOL)

    It is argued that a very necessary condition for growth and transformational development in Africa is heavy investment in human capital. It is pointed out that countries that invest much human capital to produce highly educated populaces usually reap the benefits of such in terms of high per capita GDPs, regardless of the ...

  17. Growth and development of symbiotic Arbuscular mycorrhizal fungi ...

    African Journals Online (AJOL)

    Alachlor reduced the spore germination and hyphal growth significantly at treatments higher than recommended field application rates, but non-significant effect caused by the glyphosate. The development of external hyphae was insignificantly affected in the herbicides treated soils compared with that of the untreated soil.

  18. Growth and development of abandoned babies in institutional care ...

    African Journals Online (AJOL)

    Objective: To determine the pattern of growth and development of institutionalised infants and to compare the outcome with that of infants living with their biological 1 mothers. Design: A cross-sectional survey. Setting: Seven children's homes; Kenyatta National Hospital's New Born Unit and Well Baby Clinics in Nairobi, ...

  19. Skills Development, Employment and Sustained Growth in Ghana: Sustainability Challenges

    Science.gov (United States)

    Palmer, Robert

    2009-01-01

    Against a backdrop of some two decades of sustained economic growth in Ghana, this paper argues that there are a series of sustainability challenges related to technical and vocational skills development (TVSD) that need to be addressed. This paper analyses several sustainability dimensions of TVSD related to: promoting the sustainability of…

  20. Estrogen and Growth Hormone and their Roles in Reproductive Function

    OpenAIRE

    Hüseyin Baki ÇİFTCİ

    2013-01-01

    The aim of this study was to review the effect of estrogen on growth hormone secretion and the roles of estrogen and growth hormone in reproductive function. Estrogen is the main hormone affecting growth, development, maturation and functioning of reproductive tract as well as the sexual differentiation and the behavior. Growth hormone is also important factor in sexual maturation and attainment of puberty. The impact of estrogen on growth hormone secretion has been reported in rodents and pr...

  1. Exposure to monocrotophos pesticide during sexual development causes the feminization/demasculinization of the reproductive traits and a reduction in the reproductive success of male guppies (Poecilia reticulata)

    Energy Technology Data Exchange (ETDEWEB)

    Tian, Hua; Li, Yun; Wang, Wei; Wu, Peng; Ru, Shaoguo, E-mail: rusg@ouc.edu.cn

    2012-09-01

    Monocrotophos is a highly toxic organophosphorus pesticide that has been confirmed to be an endocrine‐disrupting chemical. To evaluate the influence of this pollutant on the reproductive system of male fish, we studied the sex steroid levels, reproductive traits, sex ratio, and reproductive success in male guppies (Poecilia reticulata) exposed to 40% monocrotophos pesticide at the nominal concentrations of 0.01, 0.10, and 1.00 mg/L for 90 days from birth to adulthood in a semi‐static exposure system. Radioimmunoassay and western blot analyses demonstrated that the long‐term exposure to monocrotophos pesticide during the sexual development of male guppies caused a significant increase in 17β‐estradiol levels and consequently induced vitellogenin synthesis, suggesting the feminization of the males. Monocrotophos pesticide also caused a significant decrease in testosterone levels, which consequently inhibited testis growth and reduced the sperm count and the area and intensity of their sexually attractive orange spots, which collectively indicated the significant demasculinization of the male sexual characteristics. Furthermore, these changes in the sexual characteristics at the cellular and organ levels translated into ecologically important effects on the reproductive success at the individual level, as measured by a decrease in offspring production and survival rate. The present study provides the first evidence that monocrotophos pesticide can cause severe reproductive abnormalities in fish due to its endocrine‐disrupting action. -- Highlights: ► Monocrotophos pesticide caused an increase in 17β‐estradiol levels of male guppies. ► Monocrotophos pesticide induced vitellogenin synthesis of male guppies. ► Monocrotophos pesticide caused a decrease in testosterone levels of male guppies. ► Monocrotophos pesticide caused demasculinization of male sexual characteristics. ► Monocrotophos pesticide caused a reduction in reproductive success of male

  2. Exposure to monocrotophos pesticide during sexual development causes the feminization/demasculinization of the reproductive traits and a reduction in the reproductive success of male guppies (Poecilia reticulata)

    International Nuclear Information System (INIS)

    Tian, Hua; Li, Yun; Wang, Wei; Wu, Peng; Ru, Shaoguo

    2012-01-01

    Monocrotophos is a highly toxic organophosphorus pesticide that has been confirmed to be an endocrine‐disrupting chemical. To evaluate the influence of this pollutant on the reproductive system of male fish, we studied the sex steroid levels, reproductive traits, sex ratio, and reproductive success in male guppies (Poecilia reticulata) exposed to 40% monocrotophos pesticide at the nominal concentrations of 0.01, 0.10, and 1.00 mg/L for 90 days from birth to adulthood in a semi‐static exposure system. Radioimmunoassay and western blot analyses demonstrated that the long‐term exposure to monocrotophos pesticide during the sexual development of male guppies caused a significant increase in 17β‐estradiol levels and consequently induced vitellogenin synthesis, suggesting the feminization of the males. Monocrotophos pesticide also caused a significant decrease in testosterone levels, which consequently inhibited testis growth and reduced the sperm count and the area and intensity of their sexually attractive orange spots, which collectively indicated the significant demasculinization of the male sexual characteristics. Furthermore, these changes in the sexual characteristics at the cellular and organ levels translated into ecologically important effects on the reproductive success at the individual level, as measured by a decrease in offspring production and survival rate. The present study provides the first evidence that monocrotophos pesticide can cause severe reproductive abnormalities in fish due to its endocrine‐disrupting action. -- Highlights: ► Monocrotophos pesticide caused an increase in 17β‐estradiol levels of male guppies. ► Monocrotophos pesticide induced vitellogenin synthesis of male guppies. ► Monocrotophos pesticide caused a decrease in testosterone levels of male guppies. ► Monocrotophos pesticide caused demasculinization of male sexual characteristics. ► Monocrotophos pesticide caused a reduction in reproductive success of male

  3. [Evaluation of growth and development of institutionalized children].

    Science.gov (United States)

    Chaves, Caroline Magna Pessoa; Lima, Francisca Elisângela Teixeira; Mendonça, Larissa Bento de Araújo; Custódio, Ires Lopes; Matias, Erica Oliveira

    2013-01-01

    The study aimed to evaluate the growth and development of institutionalized children from 0-6 years old. It had a descriptive, transversal and quantitative approach, and was held in a shelter from the Bureau of Labor and Social Development of the Government of the State of Ceará, in the months of March and April 2011. The sample comprised 44 children. It the sample prevailed male children (59.1%), aged 24 to 72 months (56.8%) and with time of sheltering more than one year (72.7%). It was found that the children were in the normal range of nutrition; however, 65.9% of children did not achieve at least one of the development milestones proposed by the Ministry of Health. The study suggests a reflection on how children living in shelters are being assisted by the health team, making it necessary follow up their growth and development, in order to intervene on the alterations.

  4. The role of microbial signals in plant growth and development

    OpenAIRE

    Ortíz-Castro, Randy; Contreras-Cornejo, Hexon Angel; Macías-Rodríguez, Lourdes; López-Bucio, José

    2009-01-01

    Plant growth and development involves a tight coordination of the spatial and temporal organization of cell division, cell expansion and cell differentiation. Orchestration of these events requires the exchange of signaling molecules between the root and shoot, which can be affected by both biotic and abiotic factors. The interactions that occur between plants and their associated microorganisms have long been of interest, as knowledge of these processes could lead to the development of novel...

  5. Paths of economic development: modelling factors of endogenous growth

    OpenAIRE

    Fusari, Angelo

    1994-01-01

    This article sets out a model giving an interpretation of the engine of economic development and growth, and business cycle. Based on a peculiar concept of dynamic competition, the model explains innovation and uncertainty and describes the way equilibrating and disequilibrating processes are intertwined and operate. It also carries out concise application to successive stages of economic development, along with some econometric application, that demonstrates the degree of gene...

  6. Disorder of Sexual Development and Congenital Heart Defect in 47XYY: Clinical Disorder or Coincidence?

    Directory of Open Access Journals (Sweden)

    Hanane Latrech

    2015-01-01

    Full Text Available Background. 47XYY syndrome is a rare sex chromosome variation characterized by an additional Y chromosome. Most patients with 47XYY karyotype have normal phenotype. This disorder seems associated with a higher risk of developing behavioral and cognitive problems, tall stature, and infertility in adulthood. Sexual development disorder is a rare finding. We report a first case with an abnormal left coronary artery originating from the pulmonary artery in a 47XYY patient. Case. A one-month-old child was referred for ectopic testis and micropenis. Physical examination revealed facial dysmorphia, micropenis, and curvature of the penis with nonpalpable testis. Laboratory tests showed decreased total testosterone and anti-Mullerian hormone (AMH levels. Blood karyotyping revealed a 47XYY chromosomal formula. At the age of 3 months, the patient developed dyspnea and tachycardia. Echocardiography revealed an anomalous left coronary artery from pulmonary artery with left ventricular dysfunction requiring surgical revascularization by direct reimplantation of the left coronary artery system. Our second case was a 3-year-old child referred for hypospadias with nonpalpable left testicle. Physical examination showed hypertelorism. Blood karyotyping revealed a 47XYY chromosomal formula. Conclusion. To our knowledge, this is the first case of 47XYY syndrome associated with this congenital heart malformation and a sexual development disorder.

  7. Homosexuality via canalized sexual development: a testing protocol for a new epigenetic model.

    Science.gov (United States)

    Rice, William R; Friberg, Urban; Gavrilets, Sergey

    2013-09-01

    We recently synthesized and reinterpreted published studies to advance an epigenetic model for the development of homosexuality (HS). The model is based on epigenetic marks laid down in response to the XX vs. XY karyotype in embryonic stem cells. These marks boost sensitivity to testosterone in XY fetuses and lower it in XX fetuses, thereby canalizing sexual development. Our model predicts that a subset of these canalizing epigenetic marks stochastically carry over across generations and lead to mosaicism for sexual development in opposite-sex offspring--the homosexual phenotype being one such outcome. Here, we begin by outlining why HS has been under-appreciated as a commonplace phenomenon in nature, and how this trend is currently being reversed in the field of neurobiology. We next briefly describe our epigenetic model of HS, develop a set of predictions, and describe how epigenetic profiles of human stem cells can provide for a strong test of the model. © 2013 The Authors. Bioessays published by WILEY Periodicals, Inc.

  8. Risk factors and outcomes of chronic sexual harassment during the transition to college: Examination of a two-part growth mixture model.

    Science.gov (United States)

    McGinley, Meredith; Wolff, Jennifer M; Rospenda, Kathleen M; Liu, Li; Richman, Judith A

    2016-11-01

    A two-part latent growth mixture model was implemented in order to examine heterogeneity in the growth of sexual harassment (SH) victimization in college and university students, and the extent to which SH class membership explains substance use and mental health outcomes for certain groups of students. Demographic risk factors, mental health, and substance use were examined as they related to chronically experienced SH victimization. Incoming freshmen students (N = 2855; 58% female; 54% White) completed a survey at five time points. In addition to self-reporting gender, race, and sexual orientation, students completed measures of sexual harassment, anxiety, depression, binge drinking, and marijuana use. Overall, self-reported SH declined upon college entry, although levels rebounded by the third year of college. Results also supported a two-class solution (Infrequent and Chronic) for SH victimization. Being female, White, and a sexual minority were linked to being classified into the Chronic (relative to the Infrequent) SH class. In turn, Chronic SH class membership predicted greater anxiety, depression, and substance use, supporting a mediational model. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. Risk factors and outcomes of chronic sexual harassment during the transition to college: Examination of a two-part growth mixture model

    Science.gov (United States)

    McGinley, Meredith; Wolff, Jennifer M.; Rospenda, Kathleen M.; Liu, Li; Richman, Judith A.

    2016-01-01

    A two-part latent growth mixture model was implemented in order to examine heterogeneity in the growth of sexual harassment (SH) victimization in college and university students, and the extent to which SH class membership explains substance use and mental health outcomes for certain groups of students. Demographic risk factors, mental health, and substance use were examined as they related to chronically experienced SH victimization. Incoming freshmen students (N = 2855; 58% female; 54% White) completed a survey at five time points. In addition to self-reporting gender, race, and sexual orientation, students completed measures of sexual harassment, anxiety, depression, binge drinking, and marijuana use. Overall, self-reported SH declined upon college entry, although levels rebounded by the third year of college. Results also supported a two-class solution (Infrequent and Chronic) for SH victimization. Being female, White, and a sexual minority were linked to being classified into the Chronic (relative to the Infrequent) SH class. In turn, Chronic SH class membership predicted greater anxiety, depression, and substance use, supporting a mediational model. PMID:27712687

  10. Development Aid and Growth: An association converging to zero

    DEFF Research Database (Denmark)

    Doucouliagos,, Hristos; Paldam, Martin

    This note deals with a paradox: A literature growing exponentially in spite of the fact that it keeps finding the same result. We draw upon the findings of 106 empirical studies, of which 32 appeared in the last 4 years, to examine whether development aid generates economic growth. The studies...... report aid effects that have been steadily falling over time. The newer studies find a steady continuation of the downward trend. Using meta-regression analysis, we show that total aid has never had an effect on economic growth. Theoretically, this result might be due to simultaneity bias...

  11. Gene regulation by NMDA receptor activation in the SDN-POA neurons of male rats during sexual development.

    Science.gov (United States)

    Hsu, Hseng-Kuang; Shao, Pei-Lin; Tsai, Ke-Li; Shih, Huei-Chuan; Lee, Tzu-Ying; Hsu, Chin

    2005-04-01

    The present study was designed to identify possible signaling pathways, which may play a role in prevention of neuronal apoptosis in the sexually dimorphic nucleus of the preoptic area (SDN-POA) after physiological activation of the N-methyl-D-aspartate (NMDA) receptor. Gene response to the blockage of the NMDA receptor by an antagonist (dizocilpine hydrogen maleate; MK-801) was screened after suppression subtractive hybridization (SSH). The results showed that differential screening after SSH detected the presence of some neurotrophic genes (RNA binding motif protein 3 (RBM3), alpha-tubulin) as well as apoptosis-related genes (Bcl-2, cytochrome oxidase subunit II, cytochrome oxidase subunit III) in the SDN-POA of male rats, which were down-regulated by blocking the NMDA receptor. The RT-PCR products of the aforementioned genes in MK-801-treated males were significantly less than that in untreated males. In particular, the expression of Bcl-2 mRNA, including Bcl-2 protein, in male rats were significantly suppressed by MK-801 treatment. Moreover, the binding activity of nuclear factor kappaB (NFkappaB) was significantly higher in male rats than in females, but significantly diminished by blocking the NMDA receptor with MK-801 in male rats. No significant difference in cAMP response element-binding protein (CREB) binding activity was observed among untreated male, MK-801-treated male, untreated female and MK-801-treated female groups. These results suggest that genes regulated by NMDA receptor activation might participate in neuronal growth and/or anti-apoptosis, and support an important signaling pathway of NFkappaB activation and its target gene, Bcl-2, in preventing neuronal apoptosis in the SDN-POA of male rats during sexual development.

  12. [The development of forensic nursing from the perspective of domestic violence and sexual assault preventive policies].

    Science.gov (United States)

    Hsieh, Hsiu-Fen; Wang, Hsiu-Hung; Chang, Shu-Chen

    2013-12-01

    Forensic nursing is a new nursing specialty that provides forensic nursing service to domestic violence victims and offenders. Development of the role of forensic nurses has become urgent and necessary. The high rates of domestic violence and sexual assault in Taiwan suggest that forensic nurses have an important role to play in domestic healthcare. This article highlights the significance of forensic nursing in Taiwan in the future in terms of its origin, definitions, models, roles and functions, training and education, and previous studies. Through cooperation among academia, government, industry, and law enforcement agencies, it is expected that forensic nursing will be a positive and important area of expansion for professional nursing.

  13. Stage-specific gene expression during sexual development in Phytophthora infestans

    DEFF Research Database (Denmark)

    Fabritius, Anna-Liisa; Cvitanich, Cristina; Judelson, Howard S.

    2002-01-01

    Eight genes that are upregulated during sexual development in the heterothallic oomycete, Phytophthora infestans, were identified by suppression subtractive hybridization. Two genes showed very low but detectable expression in vegetative hyphae and became induced about 40- to >100-fold early...... revealed that the predicted products of three of the genes had similarity to proteins that influence RNA stability, namely a ribonuclease activator, the pumilio family of RNA-binding proteins and RNase H. The products of two other mating-induced genes resembled two types of Phytophthora proteins previously...

  14. THE SUSTAINABLE DEVELOPMENT OF THE BRASOV GROWTH POLE

    Directory of Open Access Journals (Sweden)

    Aida CATANA

    2016-12-01

    Full Text Available The demographic dynamics analysed in the context of the relationship between economic development and social inclusion presents an image of the sustainable development of a community as well as the manner how the financial resources have been used. With an allocation of 74.3 million euro in the programming period 2007-2013, the Brasov Growth Pole has pursued the contribution to the achievement of sustainable development since 2005 by the participation in the Agenda 21. The implementation of projects with European financing in areas such as transport, social and educational infrastructure or tourism have generated changes/demographic movements, which this paper proposes to present. The evolution of the stable population, its dynamics at the level of each locality that is part of the Brasov growth pole as well as the dynamics of the number of employees or the development of the unemployment rate are presented by the cluster analysis. The effects of the European financing obtained from Regional Operational Programme 2007-2013 are thus reflected in the sustainable development of the Brasov growth pole from the point of view of the dynamics of the population

  15. The Medical Analysis of Child Sexual Abuse Images

    Science.gov (United States)

    Cooper, Sharon W.

    2011-01-01

    Analysis of child sexual abuse images, commonly referred to as pornography, requires a familiarity with the sexual maturation rating of children and an understanding of growth and development parameters. This article explains barriers that exist in working in this area of child abuse, the differences between subjective and objective analyses,…

  16. What English Can Contribute to Understanding Sexual Identities

    Science.gov (United States)

    Ellis, Viv

    2009-01-01

    English in schools is a productive curriculum space for young people to learn about sexuality, to develop a sense of their identity as sexual beings, and to understand the importance of equality and social justice. Drawing on John Dixon's theory of "personal growth," the author (a British educator) explains how teachers' attitudes about learning…

  17. Factors Associated With Condom Use Among Sexually Active US Adults, National Survey of Family Growth, 2006-2010 and 2011-2013.

    Science.gov (United States)

    Nasrullah, Muazzam; Oraka, Emeka; Chavez, Pollyanna R; Johnson, Christopher H; DiNenno, Elizabeth

    2017-04-01

    Condom-less sex can increase the risk of acquiring or transmitting HIV. To characterize the prevalence of condom use at the most recent sex act and identify factors associated with use of a condom at the most recent sex act in adults in the United States. Data from the cross-sectional National Survey of Family Growth from cycles 2006 through 2010 and 2011 through 2013 were analyzed for sexually active men and women 18 to 44 years old who reported having sex (vaginal, anal, or oral) with an opposite-sex partner in the past 12 months. HIV-related sexual risk behaviors (SRBs) in the past 12 months included sex with at least four opposite-sex partners; exchanging sex for money or drugs; sex with an injection drug user; sex with an HIV-positive person; sex with a man who previously had sex with a man (women only); sex with a man (men only); or sex with a partner who had sex with other partners. The outcome for this analysis was condom use at the most recent anal or vaginal sex act. Overall prevalence of condom use was 24.8%; only 33.8% of adults with at least one SRB reported the use of a condom. Only 46.4% of unmarried or single men (vs 14.7% married or cohabitating men) and 32.3% unmarried or single women (vs 14.1% married or cohabitating women) with SRBs reported using a condom at the most recent sexual encounter and were less likely to use a condom at the most recent sexual encounter compared with those who did not report SRBs. We did not find a significant relation between using a condom and SRBs in married or cohabitating men and women. Our analysis adds to the literature on how condom use varies by marital status. We measured the use of condoms at the most recent sexual act, which might not reflect an individual's previous behavior of condom use. Nonetheless, condom use at the most recent sexual act has been documented in previous studies as a valid proxy of condom use over time. Continued efforts are needed to promote condom use in heterosexual adults in the

  18. Embryonic Testicular Regression Syndrome Presenting as Primary Amenorrhea: A Case Report and Review of Disorders of Sexual Development.

    Science.gov (United States)

    Hunter, J D; Pierce, S R; Calikoglu, A S; Howell, J O

    2016-08-01

    Sex development depends on the synchronous interaction of complicated genetic and hormonal events. Sex differentiation begins with sex determination, which is the assignment of the embryonic bipotential gonads as either testes or ovaries on the basis of transcriptional regulation. Hormonal regulation then directs the development of the male or female phenotype. Disruptions of this intricate cascade of events result in disorders of sexual development. A 16-year-old female adolescent presented with primary amenorrhea. Evaluation revealed female external genitalia, XY karyotype, absent gonadal tissue, and rudimentary Müllerian structures. On the basis of her constellation of findings, the most logical diagnosis was the rare embryonic testicular regression syndrome. A careful understanding of embryonic sexual development is critical to the evaluation of patients with disorders of sexual development. Copyright © 2016 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  19. BUILDING NEW BUSINESS MODELS FOR SUSTAINABLE GROWTH AND DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Taco C. R. van Someren

    2011-06-01

    Full Text Available Considered are issues of methodology and methods, as well as ideology of strategic innovation. Using the tools of this approach is offered as mechanisms to develop and build business models for sustainable socio-economic economic growth and development of different regions. The connection between key problems of sustainable development and management policy of different economic entities is studied. The consultancy company Ynnovate’s experience in addressing these issues in the EU and China is shown. It is offered to the use its experience and tools in exploring the areas of cross-border economic cooperation between territories of the Russian Far East and China

  20. Steroid hormone signaling during development has a latent effect on adult male sexual behavior in the butterfly Bicyclus anynana.

    Science.gov (United States)

    Bear, Ashley; Prudic, Kathleen L; Monteiro, Antónia

    2017-01-01

    It is well established that steroid hormones regulate sexual behavior in vertebrates via organizational and activational effects. However, whether the organizational/activational paradigm applies more broadly to the sexual behavior of other animals such as insects is not well established. Here we describe the hormonal regulation of a sexual behavior in the seasonally polyphenic butterfly Bicyclus anynana is consistent with the characteristics of an organizational effect. By measuring hormone titer levels, quantifying hormone receptor gene expression in the brain, and performing hormone manipulations, we demonstrate steroid hormone signaling early in pupal development has a latent effect on adult male sexual behavior in B. anynana. These findings suggest the organizational/activational paradigm may be more highly conserved across animal taxa than previously thought.

  1. Birth Cohort Differences in Sexual Identity Development Milestones among HIV-Negative Gay and Bisexual Men in the United States.

    Science.gov (United States)

    Grov, Christian; Rendina, H Jonathon; Parsons, Jeffrey T

    2017-10-12

    The coming-out process for gay and bisexual men (GBM) involves crossing sexual identity development (SID) milestones: (1) self-awareness of sexual attraction to the same sex, (2) self-acceptance of an identity as gay or bisexual, (3) disclosure of this sexual identity to others, and (4) having sex with someone of the same sex. We examined trends in SID milestones by birth cohort in a 2015 U.S. national sample of GBM (n = 1,023). Birth cohort was independent of when men first felt sexually attracted to someone of the same sex (median age 11 to 12). However, with the exception of age of first same-sex attraction, older cohorts tended to pass other milestones at later ages than younger cohorts. Latent class analysis (LCA) of SID milestone patterns identified three subgroups. The majority (84%) began sexual identity development with same-sex attraction around the onset of puberty (i.e., around age 10) and progressed to self-identification, same-sex sexual activity, and coming out-in that order. The other two classes felt same-sex attraction during teen years (ages 12.5 to 18.0) but achieved the remaining SID milestones later in life. For 13% of men, this was during early adulthood; for 3% of men, this was in middle adulthood. Findings highlight the need to monitor ongoing generational differences in passing SID milestones.

  2. The Impact of Clergy-Perpetrated Sexual Abuse: The Role of Gender, Development, and Posttraumatic Stress

    Science.gov (United States)

    Fogler, Jason M.; Shipherd, Jillian C.; Clarke, Stephanie; Jensen, Jennifer; Rowe, Erin

    2008-01-01

    The literature on clergy-perpetrated sexual abuse suggests that there are two modal populations of survivors: boys and adult women. We review what is known about trauma and post-traumatic stress disorder following sexual abuse and explore the different treatment needs for these two survivor groups. For children, clergy-perpetrated sexual abuse can…

  3. Safeguarding children and youth in residential and foster care: Supporting healthy sexual development

    DEFF Research Database (Denmark)

    Hansen, Gitte Riis; Grandal*, Niels

    In The Netherlands, Denmark and Scotland special awareness on the subject of sexual abuse and sexual exploitation was raised by national investigations on the prevalence and content of sexual abuse in residential and foster care. In Flanders (Belgium) it was the start of the so called Helpline 17...

  4. Energy consumption, economic growth and prices: A reassessment using panel VECM for developed and developing countries

    International Nuclear Information System (INIS)

    Mahadevan, Renuka; Asafu-Adjaye, John

    2007-01-01

    This paper reinvestigates the energy consumption-GDP growth nexus in a panel error correction model using data on 20 net energy importers and exporters from 1971 to 2002. Among the energy exporters, there was bidirectional causality between economic growth and energy consumption in the developed countries in both the short and long run, while in the developing countries energy consumption stimulates growth only in the short run. The former result is also found for energy importers and the latter result exists only for the developed countries within this category. In addition, compared to the developing countries, the developed countries' elasticity response in terms of economic growth from an increase in energy consumption is larger although its income elasticity is lower and less than unitary. Lastly, the implications for energy policy calling for a more holistic approach are discussed

  5. The Sexual Development and Education of Preschool Children: Knowledge and Opinions from Doctors and Nurses.

    Science.gov (United States)

    Kurtuncu, Meltem; Akhan, Latife Utas; Tanir, İbrahim Murat; Yildiz, Hicran

    This descriptive study was carried out in order to determine the knowledge levels and attitudes of doctors and nurses regarding children's sexual development and sex education. The study was conducted with doctors and nurses who work at various clinics of two state hospitals located in the province of Istanbul. The data collection tool consisted of 58 questions. The Statistical Program for the Social Sciences, version 18.0 (SPSS 18.0) was used for data analysis. It was determined that females comprised the majority of the respondents (61 %) and were over 36 years of age (54.1 %) (37.81 ± 8.82). Of the participants in the study, 63.5 % had bachelor's degrees and 62.1 % were medical doctors. It was determined that the number of correct responses given by the respondents regarding some behaviors observed in children aged between 3 and 6 years and children's sexual development and sex education showed significant differences according to age group ( p  = 0.007), marital status ( p  = 0.004), the status of having children ( p  = 0.004), educational status ( p  = 0.005) and occupation ( p  = 0.000). However, in a review of the study findings, it was observed that culture had an important impact on sex-related approaches and that embarrassment and shyness is very common.

  6. People with Intellectual Disabilities Talk About Sexuality: Implications for the Development of Sex Education.

    Science.gov (United States)

    Schaafsma, D; Kok, G; Stoffelen, J M T; Curfs, L M G

    2017-01-01

    Existing sex education programmes have failed in involving people with intellectual disabilities in the development of these programmes. Not involving the target population decreases the likelihood that the sex education programme will be effective. This study was conducted to assess the perspectives of people with intellectual disabilities on several sexuality-related topics. Semi-structured interviews were held with 20 people with intellectual disabilities covering topics such as: sex education, relationships, sex, social media, parenthood and support. The reported frequency of sex education the participants receive is low. Their knowledge regarding sex education is mainly limited to topics such as safe sex, contraception and STI's and tends to be superficial. Additionally, knowledge on safe sex does not always translate to safe sex behaviour. Finally, relationships are important for most participants; mainly because they don't want to be alone. Findings from both this study and literature shows that there seems to be a need for high quality sex education. Topics to consider to include are: online relationships, social media and parenthood. It would also be beneficial to focus on sexuality-related skills. Finally, to increase the effectiveness of a sex education programme, it is advisable that a theory-and evidence-based framework, such as Intervention Mapping, is used for its development.

  7. [Features of physical and sexual development and reproductive behaviour in female adolescents].

    Science.gov (United States)

    Sheliia, G P; Chavchidze, A T

    2012-01-01

    Assessment of adolescent's reproductive behaviour, identification of the factors affecting this kind of behavior, represented the main goal of the study. Comprehensive examination (n=136) and interviewing (n=825) was made in female adolescents aged 14 to 19 years (randomly formed via continuous selection). Information of the state of their health, their attitude towards child - bearing and their risky habits have been evaluated. Under the present conditions, the development of the reproductive system in female adolescents is characterized by the high frequency of menstrual irregulates (24,7%), the delayed formation of the bone pelvis (25,2%) the trend for retarted development of secondary sexual characters (12,3%), the high prevalence of chronic extra genital diseases. Thus, the results of the given study proves that reproductive disorders develop under the influence of a complex of sociomedical factors and lifestyle; They predetermine reproductive abnormalities, inadequate reproductive behaviour, the low standard of knowledge of contraception.

  8. Tongue Growth during Prenatal Development in Korean Fetuses and Embryos.

    Science.gov (United States)

    Hong, Soo Jeong; Cha, Bong Geun; Kim, Yeon Sook; Lee, Suk Keun; Chi, Je Geun

    2015-11-01

    Prenatal tongue development may affect oral-craniofacial structures, but this muscular organ has rarely been investigated. In order to document the physiology of prenatal tongue growth, we histologically examined the facial and cranial base structures of 56 embryos and 106 fetuses. In Streeter's stages 13-14 (fertilization age [FA], 28 to 32 days), the tongue protruded into the stomodeal cavity from the retrohyoid space to the cartilaginous mesenchyme of the primitive cranial base, and in Streeter's stage 15 (FA, 33 to 36 days), the tongue rapidly swelled and compressed the cranial base to initiate spheno-occipital synchondrosis and continued to swell laterally to occupy most of the stomodeal cavity in Streeter's stage 16-17 (FA, 37 to 43 days). In Streeter's stage 18-20 (FA, 44 to 51 days), the tongue was vertically positioned and filled the posterior nasopharyngeal space. As the growth of the mandible and maxilla advanced, the tongue was pulled down and protruded anteriorly to form the linguomandibular complex. Angulation between the anterior cranial base (ACB) and the posterior cranial base (PCB) was formed by the emerging tongue at FA 4 weeks and became constant at approximately 124°-126° from FA 6 weeks until birth, which was consistent with angulations measured on adult cephalograms. The early clockwise growth of the ACB to the maxillary plane became harmonious with the counter-clockwise growth of the PCB to the tongue axis during the early prenatal period. These observations suggest that human embryonic tongue growth affects ACB and PCB angulation, stimulates maxillary growth, and induces mandibular movement to achieve the essential functions of oral and maxillofacial structures.

  9. Tongue Growth during Prenatal Development in Korean Fetuses and Embryos

    Directory of Open Access Journals (Sweden)

    Soo Jeong Hong

    2015-11-01

    Full Text Available Background: Prenatal tongue development may affect oral-craniofacial structures, but this muscular organ has rarely been investigated. Methods: In order to document the physiology of prenatal tongue growth, we histologically examined the facial and cranial base structures of 56 embryos and 106 fetuses. Results: In Streeter’s stages 13–14 (fertilization age [FA], 28 to 32 days, the tongue protruded into the stomodeal cavity from the retrohyoid space to the cartilaginous mesenchyme of the primitive cranial base, and in Streeter’s stage 15 (FA, 33 to 36 days, the tongue rapidly swelled and compressed the cranial base to initiate spheno-occipital synchondrosis and continued to swell laterally to occupy most of the stomodeal cavity in Streeter’s stage 16–17 (FA, 37 to 43 days. In Streeter’s stage 18–20 (FA, 44 to 51 days, the tongue was vertically positioned and filled the posterior nasopharyngeal space. As the growth of the mandible and maxilla advanced, the tongue was pulled down and protruded anteriorly to form the linguomandibular complex. Angulation between the anterior cranial base (ACB and the posterior cranial base (PCB was formed by the emerging tongue at FA 4 weeks and became constant at approximately 124°–126° from FA 6 weeks until birth, which was consistent with angulations measured on adult cephalograms. Conclusions: The early clockwise growth of the ACB to the maxillary plane became harmonious with the counter-clockwise growth of the PCB to the tongue axis during the early prenatal period. These observations suggest that human embryonic tongue growth affects ACB and PCB angulation, stimulates maxillary growth, and induces mandibular movement to achieve the essential functions of oral and maxillofacial structures.

  10. Impact of accelerated plant growth on seed variety development

    Science.gov (United States)

    Christophersen, Eric

    1998-01-01

    The commercial lives of agricultural seed products have steadily declined in recent years. The introduction of genetically engineered crop seeds in 1966 has accentuated that trend. Widespread grower demand for genetically engineered seed requires competitive response by industry followers in order to avert market share losses to the industry leaders. Limitations on plant transformation technology, regulatory requirements and patent impediments require companies to rapidly convert transformed lines into elite commercial products. Massive multigenerational backcrossing efforts are required to distribute genetically engineered traits into a broad product mix. Significant incidents of expression failures, or ``gene silencing,'' have occurred unexpectedly, requiring product substitution strategies. First-to-market strategies, competitive response, broad germplasm conversion and rescue of product failures all share the element of urgency. Technologies which reliably accelerate product development rates can expect favorable reception by commercial seed developers. A growth chamber which dramatically accelerates the rate of plant growth is described.

  11. Effects of polymeric carbohydrates on growth and development

    DEFF Research Database (Denmark)

    Knudsen, Knud Erik Bach

    The main objective of the presentation is to provide insight into the role of polymeric carbohydrates in growth and development of pigs. Polymeric carbohydrates—starch and non-starch polysaccharides (NSP)—quantitatively represent the largest portion of the diets for pigs and are therefore...... at a slower and more constant rate and with SCFA being absorbed by passive diffusion. Type and levels of polymeric carbohydrates influence growth and development through different mechanisms; first, the proportion of starch to NSP plays an important role for the content of available energy (digestible......, metabolized and net energy); available energy relative to protein is crucial for performance and carcass quality; second, the proportion of starch to NSP will influence rate and type of metabolites (glucose vs. SCFA) deriving from carbohydrate assimilation, and finally, type of starch (types A, B, and C...

  12. Structural growth trajectories and rates of change in the first 3 months of infant brain development.

    Science.gov (United States)

    Holland, Dominic; Chang, Linda; Ernst, Thomas M; Curran, Megan; Buchthal, Steven D; Alicata, Daniel; Skranes, Jon; Johansen, Heather; Hernandez, Antonette; Yamakawa, Robyn; Kuperman, Joshua M; Dale, Anders M

    2014-10-01

    The very early postnatal period witnesses extraordinary rates of growth, but structural brain development in this period has largely not been explored longitudinally. Such assessment may be key in detecting and treating the earliest signs of neurodevelopmental disorders. To assess structural growth trajectories and rates of change in the whole brain and regions of interest in infants during the first 3 months after birth. Serial structural T1-weighted and/or T2-weighted magnetic resonance images were obtained for 211 time points from 87 healthy term-born or term-equivalent preterm-born infants, aged 2 to 90 days, between October 5, 2007, and June 12, 2013. We segmented whole-brain and multiple subcortical regions of interest using a novel application of Bayesian-based methods. We modeled growth and rate of growth trajectories nonparametrically and assessed left-right asymmetries and sexual dimorphisms. Whole-brain volume at birth was approximately one-third of healthy elderly brain volume, and did not differ significantly between male and female infants (347 388 mm3 and 335 509 mm3, respectively, P = .12). The growth rate was approximately 1%/d, slowing to 0.4%/d by the end of the first 3 months, when the brain reached just more than half of elderly adult brain volume. Overall growth in the first 90 days was 64%. There was a significant age-by-sex effect leading to widening separation in brain sizes with age between male and female infants (with male infants growing faster than females by 200.4 mm3/d, SE = 67.2, P = .003). Longer gestation was associated with larger brain size (2215 mm3/d, SE = 284, P = 4×10-13). The expected brain size of an infant born one week earlier than average was 5% smaller than average; at 90 days it will not have caught up, being 2% smaller than average. The cerebellum grew at the highest rate, more than doubling in 90 days, and the hippocampus grew at the slowest rate, increasing by 47% in 90 days. There was left

  13. Development of secondary sexual characters and their relationship to ontogeny and seasonal reproductive period in Hyphessobrycon igneus (Ostariophysi: Characiformes).

    Science.gov (United States)

    Schönhofen Longoni, L; Giora, J; Bernhardt Fialho, C

    2018-01-01

    Sexual dimorphism in size, anal-fin shape and coloration of Hyphessobrycon igneus, Characidae, were examined. Males were more frequent at larger body sizes, confirming body size as a sexually dimorphic trait. Anal-fin shape and the colour of all fins were the same for females and juveniles, differing only in adult males. Likewise, only adult males had bony hooks on fin rays; larger and more sexually mature males had the most numerous and developed hooks and hooks were most developed in degree and number during peak reproductive periods. Fin hooks regressed in number and developmental degree after the reproductive period, but restarted development with the beginning of the new reproductive period without completely disappearing. Results show that bony hooks have a development and regression cycle related to reproductive seasonality. © 2017 The Fisheries Society of the British Isles.

  14. Do multiple micronutrient interventions improve child health, growth, and development?

    Science.gov (United States)

    Ramakrishnan, Usha; Goldenberg, Tamar; Allen, Lindsay H

    2011-11-01

    Micronutrient deficiencies are common and often co-occur in many developing countries. Several studies have examined the benefits of providing multiple micronutrient (MMN) interventions during pregnancy and childhood, but the implications for programs remain unclear. The key objective of this review is to summarize what is known about the efficacy of MMN interventions during early childhood on functional outcomes, namely, child health, survival, growth, and development, to guide policy and identify gaps for future research. We identified review articles including meta-analyses and intervention studies that evaluated the benefits of MMN interventions (3 or more micronutrients) in children (child morbidity, anemia, and growth. Two studies found no effects on child mortality. The findings for respiratory illness and diarrhea are mixed, although suggestive of benefit when provided as fortified foods. There is evidence from several controlled trials (>25) and 2 meta-analyses that MMN interventions improve hemoglobin concentrations and reduce anemia, but the effects were small compared to providing only iron or iron with folic acid. Two recent meta-analyses and several intervention trials also indicated that MMN interventions improve linear growth compared to providing a placebo or single nutrients. Much less is known about the effects on MMN interventions during early childhood on motor and mental development. In summary, MMN interventions may result in improved outcomes for children in settings where micronutrient deficiencies are widespread.

  15. Fibroblast growth factor (FGF) signaling in development and skeletal diseases.

    Science.gov (United States)

    Teven, Chad M; Farina, Evan M; Rivas, Jane; Reid, Russell R

    2014-12-01

    Fibroblast growth factors (FGF) and their receptors serve many functions in both the developing and adult organism. Humans contain 18 FGF ligands and four FGF receptors (FGFR). FGF ligands are polypeptide growth factors that regulate several developmental processes including cellular proliferation, differentiation, and migration, morphogenesis, and patterning. FGF-FGFR signaling is also critical to the developing axial and craniofacial skeleton. In particular, the signaling cascade has been implicated in intramembranous ossification of cranial bones as well as cranial suture homeostasis. In the adult, FGFs and FGFRs are crucial for tissue repair. FGF signaling generally follows one of three transduction pathways: RAS/MAP kinase, PI3/AKT, or PLCγ. Each pathway likely regulates specific cellular behaviors. Inappropriate expression of FGF and improper activation of FGFRs are associated with various pathologic conditions, unregulated cell growth, and tumorigenesis. Additionally, aberrant signaling has been implicated in many skeletal abnormalities including achondroplasia and craniosynostosis. The biology and mechanisms of the FGF family have been the subject of significant research over the past 30 years. Recently, work has focused on the therapeutic targeting and potential of FGF ligands and their associated receptors. The majority of FGF-related therapy is aimed at age-related disorders. Increased understanding of FGF signaling and biology may reveal additional therapeutic roles, both in utero and postnatally. This review discusses the role of FGF signaling in general physiologic and pathologic embryogenesis and further explores it within the context of skeletal development.

  16. Reproductive and sexual health and safe motherhood in the developing world.

    Science.gov (United States)

    Shah, D; Shroff, S; Sheth, S

    1999-12-01

    The aim of this paper is to discuss the main hurdles and possible solutions concerning reproductive and sexual health and safe motherhood in the developing countries. In response to the changing global situation, a broader new concept of reproductive health has emerged. The Programme of Action of The International Conference on Population and Development (ICPD) emphasizes and highlights various aspects of reproductive health. No population in the world has met the goals of the ICPD. The problems are particularly acute in developing countries: between 20 and 40% of births are unwanted or wrongly timed, posing hardships for families and jeopardizing the health of a million women and children. An estimated 50 million induced abortions are performed each year, with some 20 million of these performed under unsafe conditions or by untrained providers. Almost 600,000 women die every year due to pregnancy-related causes, 99% of them in developing countries. Approximately 7.6 million infant deaths occur during the perinatal period each year. There are more than 333 million new cases of curable sexually transmitted diseases world-wide each year. Nearly 22 million people are estimated to be infected with the human immunodeficiency virus, of whom 14 million are in sub-Saharan Africa, with rapidly increasing numbers of infected persons in South and South-East Asia. When compared to the developed world, these figures are staggering because of barriers operating at different levels and preventing women from receiving care that is timely and of good quality. United efforts of obstetricians, pediatricians, sociologists, and different governmental and non-governmental organizations are required to achieve our targets.

  17. Future Targets for Female Sexual Dysfunction.

    Science.gov (United States)

    Farmer, Melissa; Yoon, Hana; Goldstein, Irwin

    2016-08-01

    Female sexual function reflects a dynamic interplay of central and peripheral nervous, vascular, and endocrine systems. The primary challenge in the development of novel treatments for female sexual dysfunction is the identification and targeted modulation of excitatory sexual circuits using pharmacologic treatments that facilitate the synthesis, release, and/or receptor binding of neurochemicals, peptides, and hormones that promote female sexual function. To develop an evidence-based state-of-the-art consensus report that critically integrates current knowledge of the therapeutic potential for known molecular and cellular targets to facilitate the physiologic processes underlying female sexual function. State-of-the-art review representing the opinions of international experts developed in a consensus process during a 1-year period. Expert opinion was established by grading the evidence-based medical literature, intensive internal committee discussion, public presentation, and debate. Scientific investigation is urgently needed to expand knowledge and foster development of future treatments that maintain genital tissue integrity, enhance genital physiologic responsiveness, and optimize positive subjective appraisal of internal and external sexual cues. This article critically condenses the current knowledge of therapeutic manipulation of molecular and cellular targets within biological systems responsible for female sexual physiologic function. Future treatment targets include pharmacologic modulation of emotional learning circuits, restoration of normal tactile sensation, growth factor therapy, gene therapy, stem cell-based therapies, and regenerative medicine. Concurrent use of centrally and peripherally acting therapies could optimize treatment response. Copyright © 2016 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.

  18. The role of microbial signals in plant growth and development.

    Science.gov (United States)

    Ortíz-Castro, Randy; Contreras-Cornejo, Hexon Angel; Macías-Rodríguez, Lourdes; López-Bucio, José

    2009-08-01

    Plant growth and development involves a tight coordination of the spatial and temporal organization of cell division, cell expansion and cell differentiation. Orchestration of these events requires the exchange of signaling molecules between the root and shoot, which can be affected by both biotic and abiotic factors. The interactions that occur between plants and their associated microorganisms have long been of interest, as knowledge of these processes could lead to the development of novel agricultural applications. Plants produce a wide range of organic compounds including sugars, organic acids and vitamins, which can be used as nutrients or signals by microbial populations. On the other hand, microorganisms release phytohormones, small molecules or volatile compounds, which may act directly or indirectly to activate plant immunity or regulate plant growth and morphogenesis. In this review, we focus on recent developments in the identification of signals from free-living bacteria and fungi that interact with plants in a beneficial way. Evidence has accumulated indicating that classic plant signals such as auxins and cytokinins can be produced by microorganisms to efficiently colonize the root and modulate root system architecture. Other classes of signals, including N-acyl-L-homoserine lactones, which are used by bacteria for cell-to-cell communication, can be perceived by plants to modulate gene expression, metabolism and growth. Finally, we discuss the role played by volatile organic compounds released by certain plant growth-promoting rhizobacteria in plant immunity and developmental processes. The picture that emerges is one in which plants and microbes communicate themselves through transkingdom signaling systems involving classic and novel signals.

  19. Sexual reproduction and mating-type–mediated strain development in the penicillin-producing fungus Penicillium chrysogenum

    Science.gov (United States)

    Böhm, Julia; Hoff, Birgit; O’Gorman, Céline M.; Wolfers, Simon; Klix, Volker; Binger, Danielle; Zadra, Ivo; Kürnsteiner, Hubert; Pöggeler, Stefanie; Dyer, Paul S.; Kück, Ulrich

    2013-01-01

    Penicillium chrysogenum is a filamentous fungus of major medical and historical importance, being the original and present-day industrial source of the antibiotic penicillin. The species has been considered asexual for more than 100 y, and despite concerted efforts, it has not been possible to induce sexual reproduction, which has prevented sexual crosses being used for strain improvement. However, using knowledge of mating-type (MAT) gene organization, we now describe conditions under which a sexual cycle can be induced leading to production of meiotic ascospores. Evidence of recombination was obtained using both molecular and phenotypic markers. The identified heterothallic sexual cycle was used for strain development purposes, generating offspring with novel combinations of traits relevant to penicillin production. Furthermore, the MAT1-1–1 mating-type gene, known primarily for a role in governing sexual identity, was also found to control transcription of a wide range of genes with biotechnological relevance including those regulating penicillin production, hyphal morphology, and conidial formation. These discoveries of a sexual cycle and MAT gene function are likely to be of broad relevance for manipulation of other asexual fungi of economic importance. PMID:23307807

  20. Sexual reproduction and mating-type-mediated strain development in the penicillin-producing fungus Penicillium chrysogenum.

    Science.gov (United States)

    Böhm, Julia; Hoff, Birgit; O'Gorman, Céline M; Wolfers, Simon; Klix, Volker; Binger, Danielle; Zadra, Ivo; Kürnsteiner, Hubert; Pöggeler, Stefanie; Dyer, Paul S; Kück, Ulrich

    2013-01-22

    Penicillium chrysogenum is a filamentous fungus of major medical and historical importance, being the original and present-day industrial source of the antibiotic penicillin. The species has been considered asexual for more than 100 y, and despite concerted efforts, it has not been possible to induce sexual reproduction, which has prevented sexual crosses being used for strain improvement. However, using knowledge of mating-type (MAT) gene organization, we now describe conditions under which a sexual cycle can be induced leading to production of meiotic ascospores. Evidence of recombination was obtained using both molecular and phenotypic markers. The identified heterothallic sexual cycle was used for strain development purposes, generating offspring with novel combinations of traits relevant to penicillin production. Furthermore, the MAT1-1-1 mating-type gene, known primarily for a role in governing sexual identity, was also found to control transcription of a wide range of genes with biotechnological relevance including those regulating penicillin production, hyphal morphology, and conidial formation. These discoveries of a sexual cycle and MAT gene function are likely to be of broad relevance for manipulation of other asexual fungi of economic importance.

  1. Correlation of carcass meat content with development of the reproductive system in sexually immature gilts.

    Science.gov (United States)

    Jankowiak, Hanna; Kapelański, Wojciech; Bocian, Maria; Soltész, Angéla; Balogh, Péter

    2016-09-01

    This study evaluated the correlation of carcass meat content with the development of the reproductive system in sexually immature gilts of Polish Large White (PLW) and Polish Landrace (PL) breeds. The results, obtained from three groups (I, II, III) of gilts differing in lean meat percentage, indicate an effect on fattening and slaughtering traits as well as on the morphometric characteristics of the uterus. There were statistically significant differences in the values of fattening and slaughtering traits in the groups of gilts tested. Studies on the relationship between morphometric characteristics of the reproductive system and carcass meat content showed that there was a correlation between the weight of the uterus with and without the broad ligament and the meat content of the carcass. The weight of the uterus was higher (P ≤ 0.05) in gilts with lower meat content. The negative influence of high gilt meatiness on development of the reproductive system was more pronounced in PLW gilts.

  2. Sexual Dimorphism and Sex Differences inCaenorhabditis elegansNeuronal Development and Behavior.

    Science.gov (United States)

    Barr, Maureen M; García, L Rene; Portman, Douglas S

    2018-03-01

    As fundamental features of nearly all animal species, sexual dimorphisms and sex differences have particular relevance for the development and function of the nervous system. The unique advantages of the nematode Caenorhabditis elegans have allowed the neurobiology of sex to be studied at unprecedented scale, linking ultrastructure, molecular genetics, cell biology, development, neural circuit function, and behavior. Sex differences in the C . elegans nervous system encompass prominent anatomical dimorphisms as well as differences in physiology and connectivity. The influence of sex on behavior is just as diverse, with biological sex programming innate sex-specific behaviors and modifying many other aspects of neural circuit function. The study of these differences has provided important insights into mechanisms of neurogenesis, cell fate specification, and differentiation; synaptogenesis and connectivity; principles of circuit function, plasticity, and behavior; social communication; and many other areas of modern neurobiology. Copyright © 2018 by the Genetics Society of America.

  3. Effects of combined exposure to anti-androgens on development and sexual dimorphic behaviour in rats

    DEFF Research Database (Denmark)

    Christiansen, Sofie

    the combined effects of anti-androgens and demonstrate that marked effects can occur at mixture doses below the NOAELs for the single chemicals. Since unhindered androgen action is essential for human male development in foetal life, these findings are highly relevant to human risk assessment. This must......Summary Background: Androgens are key regulators of male sexual differentiation during the in utero and early postnatal development. Exposure to endocrine disrupting chemicals (EDCs) that counteract androgen action at some stage in these periods can permanently demasculinise male foetuses and lead...... to malformations of the reproductive tract. The incidence of hypospadias (where the opening of the urethra is on the underside of the penis) in young boys has increased over the last decades but it is still unclear whether human exposure to endocrine disrupting chemicals may be responsible for this increase...

  4. How queer!--the development of gender identity and sexual orientation in LGBTQ-headed families.

    Science.gov (United States)

    Istar Lev, Arlene

    2010-09-01

    This paper focuses on the impact of heteronormativity on research and clinical theory, utilizing the case of a lesbian couple with a young gender dysphoric child as a backdrop to discuss the contextual unfolding of gender development within a lesbian parented family. The extant research on LGBTQ-headed families has minimized the complexity of children's developing gender identity and sexual orientation living in queer families, and has been guided by heteronormative assumptions that presume a less optimal outcome if the children of LGBTQ parents are gay or transgender themselves. This article challenges family therapists to recognize the enormous societal pressure on LGBTQ parents to produce heterosexual, gender-normative children, and the expectations on their children, especially those questioning their own sex or gender identities. 2010 © FPI, Inc.

  5. Disruption of a Plasmodium falciparum gene linked to male sexual development causes early arrest in gametocytogenesis.

    Science.gov (United States)

    Furuya, Tetsuya; Mu, Jianbing; Hayton, Karen; Liu, Anna; Duan, Junhui; Nkrumah, Louis; Joy, Deirdre A; Fidock, David A; Fujioka, Hisashi; Vaidya, Akhil B; Wellems, Thomas E; Su, Xin-zhuan

    2005-11-15

    A male gametocyte defect in the Plasmodium falciparum Dd2 parasite was previously discovered through the observation that all progeny clones in a Dd2 x HB3 genetic cross were the result of fertilization events between Dd2 female and HB3 male gametes. A determinant linked to the defect in Dd2 was subsequently mapped to an 800-kb segment on chromosome 12. Here, we report further mapping of the determinant to an 82-kb region and the identification of a candidate gene, P. falciparum male development gene 1 (pfmdv-1), that is expressed at a lower level in Dd2 compared with the wild-type normal male gametocyte-producing ancestor W2. Pfmdv-1 protein is sexual-stage specific and is located on the gametocyte plasma membrane, parasitophorous vacuole membrane, and the membranes of cleft-like structures within the erythrocyte. Disruption of pfmdv-1 results in a dramatic reduction in mature gametocytes, especially functional male gametocytes, with the majority of sexually committed parasites developmentally arrested at stage I. The pfmdv-1-knockout parasites show disturbed membrane structures, particularly multimembrane vesicles/tubes that likely derive from deformed cleft-like structures. Mosquito infectivity of the knockout parasites was also greatly reduced but not completely lost. The results suggest that pfmdv-1 plays a key role in gametocyte membrane formation and integrity.

  6. Resilience in community: a social ecological development model for young adult sexual minority women.

    Science.gov (United States)

    Zimmerman, Lindsey; Darnell, Doyanne A; Rhew, Isaac C; Lee, Christine M; Kaysen, Debra

    2015-03-01

    Family support and rejection are associated with health outcomes among sexual minority women (SMW). We examined a social ecological development model among young adult SMW, testing whether identity risk factors or outness to family interacted with family rejection to predict community connectedness and collective self-esteem. Lesbian and bisexual women (N = 843; 57% bisexual) between the ages of 18-25 (M = 21.4; SD = 2.1) completed baseline and 12-month online surveys. The sample identified as White (54.2%), multiple racial backgrounds (16.6%), African American (9.6%) and Asian/Asian American (3.1%); 10.2% endorsed a Hispanic/Latina ethnicity. Rejection ranged from 18 to 41% across family relationships. Longitudinal regression indicated that when outness to family increased, SMW in highly rejecting families demonstrated resilience by finding connections and esteem in sexual minority communities to a greater extent than did non-rejected peers. But, when stigma concerns, concealment motivation, and other identity risk factors increased over the year, high family rejection did not impact community connectedness and SMW reported lower collective self-esteem. Racial minority SMW reported lower community connectedness, but not lower collective self-esteem. Families likely buffer or exacerbate societal risks for ill health. Findings highlight the protective role of LGBTQ communities and normative resilience among SMW and their families.

  7. Can testosterone and corticosterone predict the rate of display of male sexual behaviour, development of secondary sexual characters and fertility potential in primary broiler breeders?

    Science.gov (United States)

    McGary Brougher, S; Estevez, I; Ottinger, M A

    2005-10-01

    1. Genetic selection for growth to enhance production may be associated with stress and with modified physiological and behavioural phenotypes which depress male primary broiler breeder fertility. 2. We hypothesised that male serum testosterone (T) and corticosterone (C) concentrations might correlate with fertility, sexual behaviour, and testicular, comb and wattle size. 3. Cockerels from two genetic strains (A and B) of primary broiler breeder were penned individually with an average of 10 females across 5 age periods (30 to 51 weeks) to evaluate male fertility, behaviour, serum T and C, and comb, wattle and testicular dimensions. 4. Strain A males had higher T at age periods 2, 4 and 5 than Strain B. Both strains had basal concentrations of C, apart from an elevated concentration for Strain B in period 5. 5. Strain B had a weak but significant, positive correlation between sexual behaviour and T and C, while Strain A males with higher C had larger combs and wattles. 6. Neither T nor C correlated with fertility. We conclude that evaluation of these endocrine factors (quantifiable measurements with the potential to correlate with fertility) alone seems insufficient to predict male fertility potential in these strains of primary broiler breeder.

  8. Explaining development aid allocation by growth: A meta study

    DEFF Research Database (Denmark)

    Doucouliagos, Hristos; Paldam, Martin

    The empirical literature explaining the driving forces behind the flows of development aid consists of (at least) 166 studies. One factor that has been analyzed in 30 of these studies is  growth in the recipient country. A priori the effect may as well be positive as negative. This is  an interes......The empirical literature explaining the driving forces behind the flows of development aid consists of (at least) 166 studies. One factor that has been analyzed in 30 of these studies is  growth in the recipient country. A priori the effect may as well be positive as negative. This is......  an interesting factor for two reasons: (1) It is relatively easy to interpret the results, and (2) it  is an important piece in the picture which suggests aid ineffectiveness. The paper is a meta-analysis of the 211 growth-aid estimates found in the 30 empirical studies. Additionally, we present new evidence...

  9. [On the relationship between population growth and economic development].

    Science.gov (United States)

    Xu, D

    1983-03-29

    People are producers as well as consumers. If we look at only one side and ignore the other, we will be unable to reach impartial conclusions concerning the population problem. An obvious and close relationship exists between population growth and national economic development. If the two do not match each other, there will be numerous contradictory problems. For example, if the population grows too fast, serious social and economic problems will be created, such as a rise in the demand for living resources, an oversupply of the labor force, unemployment, and an insufficient availability of arable land, a shortage of public housing, more demand for health care and public transportation, and cultural and educational enterprises. In addition, a rapid population growth may cause more problems for the natural environment. As a result of overpopulation, the pressure on natural resources will be intensified and may therefore cause damage to the environment and create an ecological imbalance. All the above may bring very serious difficulties and obstacles to the advancement of socialism and modernized constructions. To avoid this, we must try to solve the population problem thoroughly and maintain a balanced relationship between the population growth and economic development.

  10. Individual differences in boys' and girls' timing and tempo of puberty: modeling development with nonlinear growth models.

    Science.gov (United States)

    Marceau, Kristine; Ram, Nilam; Houts, Renate M; Grimm, Kevin J; Susman, Elizabeth J

    2011-09-01

    Pubertal development is a nonlinear process progressing from prepubescent beginnings through biological, physical, and psychological changes to full sexual maturity. To tether theoretical concepts of puberty with sophisticated longitudinal, analytical models capable of articulating pubertal development more accurately, we used nonlinear mixed-effects models to describe both the timing and tempo of pubertal development in the sample of 364 White boys and 373 White girls measured across 6 years as part of the National Institute of Child Health and Human Development Study of Early Child Care and Youth Development. Individual differences in timing and tempo were extracted with models of logistic growth. Differential relations emerged for how boys' and girls' timing and tempo of development were related to physical characteristics (body mass index, height, and weight) and psychological outcomes (internalizing problems, externalizing problems, and risky sexual behavior). Timing and tempo are associated in boys but not girls. Pubertal timing and tempo are particularly important for predicting psychological outcomes in girls but only sparsely related to boys' psychological outcomes. Results highlight the importance of considering the nonlinear nature of puberty and expand the repertoire of possibilities for examining important aspects of how and when pubertal processes contribute to development.

  11. Development of novel growth methods for halide single crystals

    Science.gov (United States)

    Yokota, Yuui; Kurosawa, Shunsuke; Shoji, Yasuhiro; Ohashi, Yuji; Kamada, Kei; Yoshikawa, Akira

    2017-03-01

    We developed novel growth methods for halide scintillator single crystals with hygroscopic nature, Halide micro-pulling-down [H-μ-PD] method and Halide Vertical Bridgman [H-VB] method. The H-μ-PD method with a removable chamber system can grow a single crystal of halide scintillator material with hygroscopicity at faster growth rate than the conventional methods. On the other hand, the H-VB method can grow a large bulk single crystal of halide scintillator without a quartz ampule. CeCl3, LaBr3, Ce:LaBr3 and Eu:SrI2 fiber single crystals could be grown by the H-μ-PD method and Eu:SrI2 bulk single crystals of 1 and 1.5 inch in diameter could be grown by the H-VB method. The grown fiber and bulk single crystals showed comparable scintillation properties to the previous reports using the conventional methods.

  12. Development and evaluation of the Women's Sexual Interest Diagnostic Interview (WSID): a structured interview to diagnose hypoactive sexual desire disorder (HSDD) in standardized patients.

    Science.gov (United States)

    DeRogatis, Leonard R; Allgood, Adam; Rosen, Raymond C; Leiblum, Sandra; Zipfel, Lisa; Guo, Chun-Yuan

    2008-12-01

    Female sexual dysfunction (FSD) is a common disorder in postmenopausal women. Currently, there is no clear "gold standard" for the diagnosis of FSD. The aim of this study was to evaluate the interrater reliability of the Women's Sexual Interest Diagnostic Interview (WSID), a new structured clinical interview designed to diagnose hypoactive sexual desire disorder (HSDD). The reliability of additional interview questions focused on the diagnosis of other types of FSD was also evaluated. The main outcome measure was the level of agreement in the diagnosis of FSD among clinical experts, between clinical experts and study coordinators, and between clinical experts and patients' self-reported interactive voice response system (IVRS) version of the WSID. Two versions of WSID were developed based on current diagnostic criteria: a clinician-administered version using a structured interview guide, and a patient self-report version using an IVRS. Three sexual medicine experts developed 20 clinical scenarios portraying cases and noncases of HSDD and other FSD diagnostic subtypes. Ten actresses with experience in standardized patient interviewing rehearsed these scenarios and performed the scripted patient roles in a standardized clinical interview with clinical experts (not the author of the script) and study coordinators, on a one-on-one basis, using the WSID interview format. In addition, all actresses completed the IVRS version of the WSID. Interviews were videotaped and viewed by the expert panel. In each instance, the diagnosis that the interview was scripted to portray was considered as the "gold standard." Kappa (kappa) coefficients were utilized to assess the level of agreement among experts, between study coordinators and the "gold standard", and between the IVRS version of the WSID and the "gold standard". All experts agreed with the gold standard diagnosis provided by the author of the script (kappa=1.0). Similarly, there was perfect agreement among the experts on

  13. Sustainable development and low carbon growth strategy for India

    International Nuclear Information System (INIS)

    Parikh, Kirit

    2012-01-01

    For India, sustainable strategy means one that is economically, environmentally and socially sustainable. This calls for rapid economic growth to deal with poverty and human development. However, the relatively meagre energy resources of the country pose a huge challenge. At the same time concern for climate change has raised the bar on the use of the one energy resource that India has in some abundance, namely coal. India's strategy for sustainable development has to explore all options of reducing energy needs, enhancing efficiency of use of conventional energy resources and develop new and renewable sources. The paper identifies various technical options, their potential roles and alternative policy measures to realize them in a cost effective manner. Even for the same objectives different policy instruments are available and how one chooses a particular instrument is often critical for the success. Self-implementing incentive compatible policy that does not create vested interests that would get entrenched should be preferred. -- Highlights: ► Energy efficiency is critical for sustainable development. ► India can reduce its emission intensity by 25 % by 2020 as proposed by India at Copenhagen. ► With a more aggressive effort even 35% reduction is attainable even with 8% or 9% growth. ► Energy efficient appliances, vehicles, buildings and industrial processes are needed. ► Policies that incentivize adoption of these pose critical challenges.

  14. The gene for a lectin-like protein is transcriptionally activated during sexual development, but is not essential for fruiting body formation in the filamentous fungus Sordaria macrospora

    Directory of Open Access Journals (Sweden)

    Cebula Patricia

    2005-11-01

    Full Text Available Abstract Background The filamentous fungus Sordaria macrospora forms complex three-dimensional fruiting bodies called perithecia that protect the developing ascospores and ensure their proper discharge. In previous microarray analyses, several genes have been identified that are downregulated in sterile mutants compared to the wild type. Among these genes was tap1 (transcript associated with perithecial development, a gene encoding a putative lectin homolog. Results Analysis of tap1 transcript levels in the wild type under conditions allowing only vegetative growth compared to conditions that lead to fruiting body development showed that tap1 is not only downregulated in developmental mutants but is also upregulated in the wild type during fruiting body development. We have cloned and sequenced a 3.2 kb fragment of genomic DNA containing the tap1 open reading frame and adjoining sequences. The genomic region comprising tap1 is syntenic to its homologous region in the closely related filamentous fungus Neurospora crassa. To determine whether tap1 is involved in fruiting body development in S. macrospora, a knockout construct was generated in which the tap1 open reading frame was replaced by the hygromycin B resistance gene hph under the control of fungal regulatory regions. Transformation of the S. macrospora wild type with this construct resulted in a tap1 deletion strain where tap1 had been replaced by the hph cassette. The knockout strain displayed no phenotypic differences under conditions of vegetative growth and sexual development when compared to the wild type. Double mutants carrying the Δtap1 allele in several developmental mutant backgrounds were phenotypically similar to the corresponding developmental mutant strains. Conclusion The tap1 transcript is strongly upregulated during sexual development in S. macrospora; however, analysis of a tap1 knockout strain shows that tap1 is not essential for fruiting body formation in S. macrospora.

  15. The Use of Biofuel for Sustainable Growth in Developing Countries

    Science.gov (United States)

    Tsang, J.

    2014-12-01

    The biofuel industry is divided into four categories comprising of feedstocks used in 1st and 2nd generation bioethanol and biodiesel. In order to identify and quantify each biofuel feedstock's potential for sustainable growth, each were evaluated according to self-developed social, financial, and environmental criteria. From the investigation and analysis carried out, 1st generation biodiesel and bioethanol were determined to be feedstocks not capable of facilitating sustainable growth. Results showed low earnings before interest, taxes, depreciation and amortization (EBITDA) of -0.5 to 1 USD per gallon for biodiesel and 0.25 to 0.5 USD per gallon for bioethanol. Results also showed a poor return on asset (ROA). The energy required to produce one MJ of 1st generation biofuel fuel was at least 0.4 MJ, showing poor energy balance. Furthermore, high land, water, pesticide, and fertilizer requirements strained surrounding ecosystems by affecting the food web, thus reducing biodiversity. Over 55% of land used by the biodiesel industry in Indonesia and Malaysia involved the deforestation of local rainforests. This not only displaced indigenous organisms from their habitat and decreased their scope of nutrition, but also contributed to soil erosion and increased the probability of flooding. If left unregulated, imbalances in the ecosystem due to unsustainable growth will result in a permanent reshaping of tropical rainforest ecosystems in Southeast Asia. Algae, an example of 2nd generation biodiesel feedstock, was concluded to be the biofuel feedstock most capable of supporting sustainable growth. This is due to its low production costs of $1-1.5/gal, high biological productivity of 5000 gallons of biodiesel per acre per year, and high ROA of 25-35%. Additionally, algae's adaptability to varying environmental conditions also makes it an appealing candidate for businesses in developing countries, where access to resource supplies is unstable. Additionally, its reduced net

  16. Ecological Network Analysis for Economic Systems: Growth and Development and Implications for Sustainable Development

    Science.gov (United States)

    Huang, Jiali; Ulanowicz, Robert E.

    2014-01-01

    The quantification of growth and development is an important issue in economics, because these phenomena are closely related to sustainability. We address growth and development from a network perspective in which economic systems are represented as flow networks and analyzed using ecological network analysis (ENA). The Beijing economic system is used as a case study and 11 input–output (I-O) tables for 1985–2010 are converted into currency networks. ENA is used to calculate system-level indices to quantify the growth and development of Beijing. The contributions of each direct flow toward growth and development in 2010 are calculated and their implications for sustainable development are discussed. The results show that during 1985–2010, growth was the main attribute of the Beijing economic system. Although the system grew exponentially, its development fluctuated within only a small range. The results suggest that system ascendency should be increased in order to favor more sustainable development. Ascendency can be augmented in two ways: (1) strengthen those pathways with positive contributions to increasing ascendency and (2) weaken those with negative effects. PMID:24979465

  17. Ecological network analysis for economic systems: growth and development and implications for sustainable development.

    Science.gov (United States)

    Huang, Jiali; Ulanowicz, Robert E

    2014-01-01

    The quantification of growth and development is an important issue in economics, because these phenomena are closely related to sustainability. We address growth and development from a network perspective in which economic systems are represented as flow networks and analyzed using ecological network analysis (ENA). The Beijing economic system is used as a case study and 11 input-output (I-O) tables for 1985-2010 are converted into currency networks. ENA is used to calculate system-level indices to quantify the growth and development of Beijing. The contributions of each direct flow toward growth and development in 2010 are calculated and their implications for sustainable development are discussed. The results show that during 1985-2010, growth was the main attribute of the Beijing economic system. Although the system grew exponentially, its development fluctuated within only a small range. The results suggest that system ascendency should be increased in order to favor more sustainable development. Ascendency can be augmented in two ways: (1) strengthen those pathways with positive contributions to increasing ascendency and (2) weaken those with negative effects.

  18. The sexual consent scale-revised: development, reliability, and preliminary validity.

    Science.gov (United States)

    Humphreys, Terry P; Brousseau, Mélanie M

    2010-09-01

    The Sexual Consent Scale-Revised (SCS-R) measures an individual's beliefs, attitudes, and behaviors with respect to how sexual consent should be and is negotiated between sexual partners. This study extends previous research on sexual consent by revising a scale using the Theory of Planned Behavior (Ajzen, 1991, 2001, 2005) as its theoretical foundation. The psychometric properties of the SCS-R were established using factor analysis, construct validity tests, as well as internal consistency and test-retest reliability. Five factors emerged: perceived behavioral control, positive attitude toward establishing consent, sexual consent norms, indirect consent behaviors, and awareness of consent. Results indicated that the SCS-R can be useful for examining a variety of research questions relating to sexual consent.

  19. Growth and development in children born very low birthweight.

    Science.gov (United States)

    Scharf, Rebecca J; Stroustrup, Annemarie; Conaway, Mark R; DeBoer, Mark D

    2016-09-01

    To examine the relationships between growth (birth to age 2 years) and developmental outcomes in children born with very low birthweight (VLBW). Motor and mental development in children born with VLBW were regressed on anthropometric measurements at birth, 9 months and 2 years using multivariable regression. The Early Childhood Longitudinal Study-Birth Cohort, a longitudinal cohort, community sample, designed to be representative of children born across the USA. 950 children born with VLBW (children exhibited poor growth, with length-for-age z-scores children at 9 months (adjusted for prematurity) and 34.2% of children at 2 years. Compared with children having z-scores >-2, children with growth shortfalls in head circumference, length and weight had a higher adjusted OR (aOR) of low Bayley motor scores at 9 months and 2 years (aOR ranging from 1.8 to 3.3, all pchildren born with VLBW. While careful length measures may be a particularly useful marker, deficits in all anthropometric measures were risk factors for developmental delays. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  20. The development and evaluation of a sexual harassment contact person training package.

    Science.gov (United States)

    Blaxall, M C; Parsonson, B S; Robertson, N R

    1993-04-01

    The effectiveness of a training package to teach listening and helping skills to three pairs of sexual harrassment contact person trainees was evaluated, using a multiple probe design. The training package comprised five components: behavioral specifications, rationales, situational examples, study guides, and role-play exercises, provided in a written instructional format based on guidelines developed by Fawcett and Fletcher. Evaluation involved pre- and posttraining measures of target behavior occurrence, relevant knowledge, and self-rated confidence level. Ratings of performance were also provided by potential consumers as a measure of social validity. Findings indicated that the package was effective in increasing listening and helping skills, knowledge, and confidence of trainees and that skills generalized to new simulated cases and were maintained over time.

  1. Development and Pilot Test of a Commercial Sexual Exploitation Prevention Tool: A Brief Report.

    Science.gov (United States)

    Murphy, Molly; Bennett, Nicole; Kottke, Melissa

    2016-01-01

    Commercial sexual exploitation of children (CSEC) is a persistent problem in the United States, yet few youth-oriented CSEC prevention tools exist. The objectives of this project were to develop an educational website about CSEC for adolescents and evaluate it through pre- and posttests of adolescents' knowledge and attitudes about CSEC. Results demonstrated increases in participants' CSEC knowledge and decreases in their tolerance of CSEC after navigating the website and viewing an embedded video. Qualitative and quantitative results suggest that CSEC is deemed an important issue by adolescents and web-based content is a relevant and useful mode through which to educate adolescents about CSEC. Consideration should be given to further exploration of this and other tools for CSEC prevention tailored to adolescents' needs and preferences.

  2. Differences in teenage pregnancy rates among five developed countries: the roles of sexual activity and contraceptive use.

    Science.gov (United States)

    Darroch, J E; Singh, S; Frost, J J

    2001-01-01

    Adolescent pregnancy, birth, abortion and sexually transmitted disease (STD) rates are much higher in the United States than in most other developed countries. Government statistics or nationally representative survey data were supplemented with data collected by private organizations or for regional or local populations to conduct studies of adolescent births, abortions, sexual activity and contraceptive use in Canada, the United States, Sweden, France and Great Britain. Adolescent childbearing is more common in the United States (22% of women reported having had a child before age 20) than in Great Britain (15%), Canada (11%), France (6%) and Sweden (4%); differences are even greater for births to younger teenagers. A lower proportion of teenage pregnancies are resolved through abortion in the United States than in the other countries; however, because of their high pregnancy rate, U.S. teenagers have the highest abortion rate. The age of sexual debut varies little across countries, yet American teenagers are the most likely to have multiple partners. A greater proportion of U.S. women reported no contraceptive use at either first or recent intercourse (25% and 20%, respectively) than reported nonuse in France (11% and 12%, respectively), Great Britain (21% and 4%, respectively) and Sweden (22% and 7%, respectively). Data on contraceptive use are more important than data on sexual activity in explaining variation in levels of adolescent pregnancy and childbearing among the five developed countries; however, the higher level of multiple sexual partnership among American teenagers may help explain their higher STD rates.

  3. A Meta-Analysis of Risky Sexual Behaviour among Male Youth in Developing Countries

    OpenAIRE

    Berhan, Yifru; Berhan, Asres

    2015-01-01

    The purpose of this meta-analysis was to assess the association between risky sexual behaviour and level of education and economic status in male youth. Previous tests of the association of risky sexual behaviour with levels of education and economic status have yielded inconsistent results. Using data from 26 countries, from both within and outside Africa, we performed a meta-analysis with a specific focus on male youths’ risky sexual behaviour. We applied a random effects analytic model and...

  4. Sexual Identity Development among Gay, Lesbian, and Bisexual Youths: Consistency and Change Over Time

    OpenAIRE

    Rosario, Margaret; Schrimshaw, Eric W.; Hunter, Joyce; Braun, Lisa

    2006-01-01

    A longitudinal report of 156 gay, lesbian, and bisexual youths examined changes in sexual identity over time. Fifty-seven percent of the youths remained consistently self-identified as gay/lesbian, 18% transited from bisexual to gay/lesbian, and 15% consistently identified as bisexual over time. Although youths who consistently identified as gay/lesbian did not differ from other youths on time since experiencing sexual developmental milestones, they reported current sexual orientation and sex...

  5. Biocontrol of Sugarcane Smut Disease by Interference of Fungal Sexual Mating and Hyphal Growth Using a Bacterial Isolate.

    Science.gov (United States)

    Liu, Shiyin; Lin, Nuoqiao; Chen, Yumei; Liang, Zhibin; Liao, Lisheng; Lv, Mingfa; Chen, Yufan; Tang, Yingxin; He, Fei; Chen, Shaohua; Zhou, Jianuan; Zhang, Lianhui

    2017-01-01

    Sugarcane smut is a fungal disease caused by Sporisorium scitamineum , which can cause severe economic losses in sugarcane industry. The infection depends on the mating of bipolar sporida to form a dikaryon and develops into hyphae to penetrate the meristematic tissue of sugarcane. In this study, we set to isolate bacterial strains capable of blocking the fungal mating and evaluate their potential in control of sugarcane smut disease. A bacterial isolate ST4 from rhizosphere displayed potent inhibitory activity against the mating of S. scitamineum bipolar sporida and was selected for further study. Phylogenetic analyses and biochemical characterization showed that the isolate was most similar to Pseudomonas guariconensis . Methanol extracts from minimum and potato dextrose agar (PDA) agar medium, on which strain ST4 has grown, showed strong inhibitory activity on the sexual mating of S. scitamineum sporida, without killing the haploid cells MAT-1 or MAT-2. Further analysis showed that only glucose, but not sucrose, maltose, and fructose, could support strain ST4 to produce antagonistic chemicals. Consistent with the above findings, greenhouse trials showed that addition of 2% glucose to the bacterial inoculum significantly increased the strain ST4 biocontrol efficiency against sugarcane smut disease by 77% than the inoculum without glucose. The results from this study depict a new strategy to screen for biocontrol agents for control and prevention of the sugarcane smut disease.

  6. Preliminary development of a scale to measure stigma relating to sexually transmitted infections among women in a high risk neighbourhood

    Directory of Open Access Journals (Sweden)

    Patrick David M

    2008-11-01

    Full Text Available Abstract Background As stigma is a socially constructed concept, it would follow that stigma related to sexual behaviours and sexually transmitted infections would carry with it many of the gender-based morals that are entrenched in social constructs of sexuality. In many societies, women tend to be judged more harshly with respect to sexual morals, and would therefore have a different experience of stigma related to sexual behaviours as compared to men. While a variety of stigma scales exist for sexually transmitted infections (STIs in general; none incorporate these female-specific aspects. The objective of this study was to develop a scale to measure the unique experience of STI-related stigma among women. Methods A pool of items was identified from qualitative and quantitative literature on sexual behaviour and STIs among women. Women attending a social evening program at a local community health clinic in a low-income neighbourhood with high prevalence of substance use were passively recruited to take part in a cross-sectional structured interview, including questions on sexual behaviour, sexual health and STI-related stigma. Exploratory factor analysis was used to identify stigma scales, and descriptive statistics were used to assess the associations of demographics, sexual and drug-related risk behaviours with the emerging scales. Results Three scales emerged from exploratory factor analysis – female-specific moral stigma, social stigma (judgement by others and internal stigma (self-judgement – with alpha co-efficients of 0.737, 0.705 and 0.729, respectively. In this population of women, internal stigma and social stigma carried higher scores than female-specific moral stigma. Aboriginal ethnicity was associated with higher internal and female-specific moral stigma scores, while older age (>30 years was associated with higher female-specific moral stigma scores. Conclusion Descriptive statistics indicated an important influence of

  7. Genomic imprinting in development, growth, behavior and stem cells.

    Science.gov (United States)

    Plasschaert, Robert N; Bartolomei, Marisa S

    2014-05-01

    Genes that are subject to genomic imprinting in mammals are preferentially expressed from a single parental allele. This imprinted expression of a small number of genes is crucial for normal development, as these genes often directly regulate fetal growth. Recent work has also demonstrated intricate roles for imprinted genes in the brain, with important consequences on behavior and neuronal function. Finally, new studies have revealed the importance of proper expression of specific imprinted genes in induced pluripotent stem cells and in adult stem cells. As we review here, these findings highlight the complex nature and developmental importance of imprinted genes.

  8. Peculiarities of sexual development and reproductive function in young women with childhood onset weight problems.

    Science.gov (United States)

    Chikvaidze, N; Kristesashvili, J; Gegechkori, M

    2014-10-01

    The risks of reproductive problems are higher in underweight and overweight or obese women, especially in case of rapid weight gain or loss. But evidence is inconsistent especially in relation to the effect of age of body weight changes. The aim of the study was detection of peculiarities of sexual development and reproductive function in underweight and overweight/obese females with childhood thinness or childhood obesity. 103 young females (48 - with low BMI, 55 - with high BMI) with different reproductive problems were examined prospectively. In all investigated patients full clinical examination was held, including body mass index (BMI), type of body fat distribution (waist-to-hip ratio), age of body weight changes, assessment of hirsutism, acne, stretch marks and hyperpigmentation, menstrual disturbances and fertility problems were recorded and gynecological ultrasound was performed. There was no difference established according to the age of menarche and types of menstrual disturbances between the groups of low BMI and high BMI females (p>.05). The correlation was established between the onset of menstrual disruption and progression of changes in body mass (R=.448, p=.005). Hirsutism, stretch marks and acantosis nigricans (hyperpigmentation) were exhibited significantly more frequently in the patients with high BMI (pdistribution of acne was almost the same in the study groups (p>.05). 74.5% of overweight and obese patients had upper body fat distribution (waist-to-hip ratio > 0.8), whilst underweight patients had mostly equal (66.7%) or lower body fat distribution (31.3%) (p=.000). Polycystic ovarian syndrome (PCOS) and metabolic syndrome (MS) was the most frequent in overweight and obese patients, whilst non-classical congenital adrenal hyperplasia (NCAH) and ovarian dysfunction prevailed in the underweight females (p<.05). Infertility was mostly observed in patients with high BMI (p<.05). In conclusion, the peculiarities of sexual development and menstrual

  9. Blue light acts as a double-edged sword in regulating sexual development of Hypocrea jecorina (Trichoderma reesei.

    Directory of Open Access Journals (Sweden)

    Chia-Ling Chen

    Full Text Available The industrially important cellulolytic filamentous fungus Trichoderma reesei is the anamorph of the pantropical ascomycete Hypocrea jecorina. H. jecorina CBS999.97 strain undergoes a heterothallic reproductive cycle, and the mating yields fertilized perithecia imbedded in stromata. Asci in the perithecia contain 16 linearly arranged ascospores. Here, we investigated H. jecorina sexual development under different light regimes, and found that visible light was dispensable for sexual development (stroma formation and ascospore discharge. By contrast, constant illumination inhibited stroma formation, and an interruption of the darkness facilitated timely stroma formation in a 12 h/12 h light-dark photoperiod. The results of genetic analyses further revealed that H. jecorina blue-light photoreceptors (BLR1, BLR2 and the photoadaptation protein ENV1 were not essential for sexual development in general. BLR1, BLR2 and ENV1 are orthologues of the conserved Neurospora crassa WC-1, WC-2 and VVD, respectively. Moreover, BLR1 and BLR2 mediate both positive and negative light-dependent regulation on sexual development, whereas ENV1 is required for dampening the light-dependent inhibitory effect in response to changes in illumination. Comparative genome-wide microarray analysis demonstrated an overview of light-dependent gene expression versus sexual potency in CBS999.97 (MAT1-2 haploid cells. Constant illumination promotes abundant asexual conidiation and high levels of hpp1 transcripts. hpp1 encodes a h (hybrid-type propheromone that exhibits features of both yeast a and a pheromone precursors. Deletion of hpp1 could rescue stroma formation but not ascospore generation under constant illumination. We inferred that the HPP1-dependent pheromone signaling system might directly prevent stroma formation or simply disallow the haploid cells to acquire sexual potency due to abundant asexual conidiation upon constant illumination.

  10. Counseling and Human Sexuality: A Training Model.

    Science.gov (United States)

    Fyfe, Bill

    1980-01-01

    Presents a counseling and human sexuality course model that provides counselors with an information base in human sexuality and assists them in exploring the emotional aspects of sexuality. Human sexuality is a vital aspect of personal development. (Author)

  11. An exploration of the judgement of sexual situations by adolescents with autism spectrum disorders versus typically developing adolescents

    NARCIS (Netherlands)

    Visser, Kirsten; Greaves-Lord, Kirstin; Tick, Nouchka T.; Verhulst, Frank C.; Maras, Athanasios; van der Vegt, Esther J M

    2017-01-01

    Background Inappropriate sexual behaviour, sexual problems and sexual victimization in adolescents with autism spectrum disorders (ASD) is regularly reported in previous research, but little is known about factors associated with these problems, nor about factors associated with a healthy sexuality

  12. How to improve the validity of sexual behaviour reporting: systematic review of questionnaire delivery modes in developing countries.

    Science.gov (United States)

    Langhaug, Lisa F; Sherr, Lorraine; Cowan, Frances M

    2010-03-01

    To systematically review comparative research from developing countries on the effects of questionnaire delivery mode. We searched Medline, EMbase and PsychINFO and ISSTDR conference proceedings. Randomized control trials and quasi-experimental studies were included if they compared two or more questionnaire delivery modes, were conducted in a developing country, reported on sexual behaviours and occurred after 1980. A total of 28 articles reporting on 26 studies met the inclusion criteria. Heterogeneity of reported trial outcomes between studies made it inappropriate to combine trial outcomes. Eighteen studies compared audio computer-assisted survey instruments (ACASI) or its derivatives [personal digital assistant (PDA) or computer-assisted personal interview (CAPI)] against another self-administered questionnaires, face-to-face interviews or random response technique. Despite wide variation in geography and populations sampled, there was strong evidence that computer-assisted interviews lowered item-response rates and raised rates of reporting sensitive behaviours. ACASI also improved data entry quality. A wide range of sexual behaviours were reported including vaginal, oral, anal and/or forced sex, age of sexual debut, condom use at first and/or last sex. Validation of self-reports using biomarkers was rare. These data reaffirm that questionnaire delivery modes do affect self-reported sexual behaviours and that use of ACASI can significantly reduce reporting bias. Its acceptability and feasibility in developing country settings should encourage researchers to consider its use when conducting sexual health research. Triangulation of self-reported data using biomarkers is recommended. Standardizing sexual behaviour measures would allow for meta-analysis.

  13. Bilateral asymmetry of the humerus during growth and development.

    Science.gov (United States)

    Blackburn, Amanda

    2011-08-01

    The development of handedness throughout growth can be investigated by using bilateral asymmetry of the humerus as a proxy for this trait. A large skeletal sample of nonadults from English archaeological sites was examined using standard metric techniques to assess when right-sided asymmetry first appears in the human skeleton. Results of this work indicate a change in directional asymmetry during growth and development, with infants and young children exhibiting no significant asymmetry and older children and adolescents demonstrating right-sidedness. This trend is consistent with what has been observed in previous studies of upper limb asymmetry in skeletal material and behaviorally in living children, adding further strength to the premise that biomechanical forces strongly influence bilateral asymmetry in the upper limb bones. Variability in the magnitude of asymmetry between different features of the humerus was also noted. This characteristic can be explained by differing degrees of genetic canalization, with length and articular dimensions being more strongly canalized than diaphyseal properties. Copyright © 2011 Wiley-Liss, Inc.

  14. The growth and development of gerontological nurse leaders in policy.

    Science.gov (United States)

    Perez, G Adriana; Mason, Diana J; Harden, J Taylor; Cortes, Tara A

    2017-11-03

    The National Hartford Center of Gerontological Nursing Excellence (NHCGNE) Scholars/Fellows Award Program was designed to promote the growth and development of nurse scientists, educators, and leaders in aging. McBride's conceptual framework of the growth and development of nurse leaders was used to examine the NHCGNE impact on health and aging policy work among scholars/fellows, including barriers, facilitators, and resources. A multimethod two-phased approach included an online survey (phase I) focused on research and policy impact at local, state, or national level. Telephone interviews (phase II) were conducted to further understand the nature, depth, and focus of respondents' policy work. Based on our findings, we propose multilevel recommendations for advancing nurse scientists' capacity to be leaders in shaping policy. Keen research skills are influential in policy advancement but not sufficient to advance policy. Preparing nurse scientists with competencies in translating research into policy can ultimately transform health and health care for older adults. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Development and psychometric evaluation of the sexual knowledge and attitudes scale for premarital couples (SKAS-PC: An exploratory mixed method study

    Directory of Open Access Journals (Sweden)

    Zohreh Sadat

    2018-02-01

    Full Text Available Background: Designing a valid and reliable questionnaire that allows a fair evaluation of sexual knowledge and attitudes and develop a proper sexual educational program is necessary. Objective: The present study was designed to develop and psychometric evaluation of the sexual knowledge and attitudes scale for premarital couples. Materials and Methods: An exploratory mixed method study was conducted in two phases; in the first, in order to develop a questionnaire an item pool was generated on sexual knowledge and attitudes through focus group discussions and individual interviews. In the second phase, the psychometric properties of the questionnaire were examined. For this purpose, face validity, content validity as well as construct validity were conducted. Reliability was assessed by the Cronbach’s alpha coefficient to assess internal consistency and test-retest reliability. Results: In the first phase an item pool with 88 questions was generated (sexual knowledge 45 items and sexual attitudes 43 items. In the second phase, the number of final items reduced to 33 and 34 items of sexual knowledge and sexual attitudes respectively, through exploratory factor analysis (EFA. Five factors for sexual knowledge and six factors for sexual attitudes identified by EFA. The Cronbach’s alpha coefficient for two sections was 0.84 and 0.81 respectively. The test- retest correlations for sexual knowledge and sexual attitude was 0.74 and 0.82 respectively. Conclusion: The findings suggest that the Sexual Knowledge and Attitudes Scale for Premarital Couples is a valid and reliable instrument. Further studies are needed to establish stronger psychometric properties for the questionnaire.

  16. Partner notification for sexually transmitted infections in developing countries: a systematic review

    Directory of Open Access Journals (Sweden)

    Vermund Sten H

    2010-01-01

    Full Text Available Abstract Background The feasibility and acceptability of partner notification (PN for sexually transmitted infections (STIs in developing countries was assessed through a comprehensive literature review, to help identify future intervention needs. Methods The Medline, Embase, and Google Scholar databases were searched to identify studies published between January 1995 and December 2007 on STI PN in developing countries. A systematic review of the research extracted information on: (1 willingness of index patients to notify partners; (2 the proportion of partners notified or referred; (3 client-reported barriers in notifying partners; (4 infrastructure barriers in notifying partners; and (5 PN approaches that were evaluated in developing countries. Results Out of 609 screened articles, 39 met our criteria. PN outcome varied widely and was implemented more often for spousal partners than for casual or commercial partners. Reported barriers included sociocultural factors such as stigma, fear of abuse for having an STI, and infrastructural factors related to the limited number of STD clinics, and trained providers and reliable diagnostic methods. Client-oriented counselling was found to be effective in improving partner referral outcomes. Conclusions STD clinics can improve PN with client-oriented counselling, which should help clients to overcome perceived barriers. The authors speculate that well-designed PN interventions to evaluate the impact on STI prevalence and incidence along with cost-effectiveness components will motivate policy makers in developing countries to allocate more resources towards STI management.

  17. Partner notification for sexually transmitted infections in developing countries: a systematic review.

    Science.gov (United States)

    Alam, Nazmul; Chamot, Eric; Vermund, Sten H; Streatfield, Kim; Kristensen, Sibylle

    2010-01-18

    The feasibility and acceptability of partner notification (PN) for sexually transmitted infections (STIs) in developing countries was assessed through a comprehensive literature review, to help identify future intervention needs. The Medline, Embase, and Google Scholar databases were searched to identify studies published between January 1995 and December 2007 on STI PN in developing countries. A systematic review of the research extracted information on: (1) willingness of index patients to notify partners; (2) the proportion of partners notified or referred; (3) client-reported barriers in notifying partners; (4) infrastructure barriers in notifying partners; and (5) PN approaches that were evaluated in developing countries. Out of 609 screened articles, 39 met our criteria. PN outcome varied widely and was implemented more often for spousal partners than for casual or commercial partners. Reported barriers included sociocultural factors such as stigma, fear of abuse for having an STI, and infrastructural factors related to the limited number of STD clinics, and trained providers and reliable diagnostic methods. Client-oriented counselling was found to be effective in improving partner referral outcomes. STD clinics can improve PN with client-oriented counselling, which should help clients to overcome perceived barriers. The authors speculate that well-designed PN interventions to evaluate the impact on STI prevalence and incidence along with cost-effectiveness components will motivate policy makers in developing countries to allocate more resources towards STI management.

  18. Finnish Official Development Aid for Sexual and Reproductive Health and Rights in Sub-Saharan Africa

    Directory of Open Access Journals (Sweden)

    Riikka Shemeikka

    2010-01-01

    Full Text Available Finland is one of the donor countries that is most supportive in family planning (FP, Sexual and Reproductive Health and Rights (SRHR and gender issues. This study examines Finnish ODA for FP and SRHR: its decision-making structure, other stakeholders and funding levels. Data consists of documents from the Ministry for Foreign Affairs (MFA and interviews conducted at the MFA and with other experts. While Parliament decides on the overall level of ODA funding, the Minister for Foreign Trade and Development has considerable autonomy. Other stakeholders such as the All-Party Parliamentary Group on Population and Development and the Family Federation of Finland (Vestliitto engage in advocacy work and have influenced development policy. Although the Development Policy 2007 mentions the importance of health and SRHR issues and HIV/AIDS is a cross-cutting issue, interviewees stated that the importance of health and SRHR in ODA has declined and that the implementation of cross-cutting issues is challenging. Multilateral funding for UNFPA, UNAIDS and GFATM, and thus the proportion of SRHR funding within the health sector, is however currently rising. Funding for population-related activities has increased and represented 4.8% of Finlands total ODA in 2009. Almost all of this funding is directed towards basic reproductive health and HIV/AIDS issues and the majority is directed through multilateral channels (78% in 2009, mainly UNFPA and UNAIDS. IPPF, Ipas and Marie Stopes International also receive support.

  19. Involvement of Stat3 in mouse brain development and sexual dimorphism: a proteomics approach.

    Science.gov (United States)

    Di Domenico, Fabio; Casalena, Gabriella; Sultana, Rukhsana; Cai, Jian; Pierce, William M; Perluigi, Marzia; Cini, Chiara; Baracca, Alessandra; Solaini, Giancarlo; Lenaz, Giorgio; Jia, Jia; Dziennis, Suzan; Murphy, Stephanie J; Alkayed, Nabil J; Butterfield, D Allan

    2010-11-29

    Although the role of STAT3 in cell physiology and tissue development has been largely investigated, its involvement in the development and maintenance of nervous tissue and in the mechanisms of neuroprotection is not yet known. The potentially wide range of STAT3 activities raises the question of tissue- and gender-specificity as putative mechanisms of regulation. To explore the function of STAT3 in the brain and the hypothesis of a gender-linked modulation of STAT3, we analyzed a neuron-specific STAT3 knockout mouse model investigating the influence of STAT3 activity in brain protein expression pattern in both males and females in the absence of neurological insult. We performed a proteomic study aimed to reveal the molecular pathways directly or indirectly controlled by STAT3 underscoring its role in brain development and maintenance. We identified several proteins, belonging to different neuronal pathways such as energy metabolism or synaptic transmission, controlled by STAT3 that confirm its crucial role in brain development and maintenance. Moreover, we investigated the different processes that could contribute to the sexual dimorphic behavior observed in the incidence of neurological and mental disease. Interestingly both STAT3 KO and gender factors influence the expression of several mitochondrial proteins conferring to mitochondrial activity high importance in the regulation of brain physiology and conceivable relevance as therapeutic target. Copyright © 2010 Elsevier B.V. All rights reserved.

  20. Polyubiquitin is required for growth, development and pathogenicity in the rice blast fungus Magnaporthe oryzae.

    Science.gov (United States)

    Oh, Yeonyee; Franck, William L; Han, Sang-Oh; Shows, Angela; Gokce, Emine; Muddiman, David C; Dean, Ralph A

    2012-01-01

    Protein ubiquitination, which is highly selective, regulates many important biological processes including cellular differentiation and pathogenesis in eukaryotic cells. Here, we integrated pharmacological, molecular and proteomic approaches to explore the role of ubiquitination in Magnaporthe oryzae, the leading fungal disease of rice world-wide. Inhibition of ubiquitin-mediated proteolysis using the 26S proteasome inhibitor, Bortezomib, significantly attenuated conidia germination, appressorium formation and pathogenicity in M. oryzae. Gene expression analysis revealed that many genes associated with protein ubiquitination were developmentally regulated during conidia germination. Only a few, including a polyubiquitin encoding gene, MGG_01282, were more abundantly expressed during appressorium formation and under nitrogen starvation. Targeted gene deletion of MGG_01282, in addition to a significant reduction in protein ubiquitination as determined by immuno blot assays, resulted in pleiotropic effects on M. oryzae including reduced growth and sporulation, abnormal conidia morphology, reduced germination and appressorium formation, and the inability to cause disease. Mutants were also defective in sexual development and were female sterile. Using mass spectrometry, we identified 63 candidate polyubiquitinated proteins under nitrogen starvation, which included overrepresentation of proteins involved in translation, transport and protein modification. Our study suggests that ubiquitination of target proteins plays an important role in nutrient assimilation, development and pathogenicity of M. oryzae.

  1. Sexual orientation and boyhood gender conformity: development of the Boyhood Gender Conformity Scale (BGCS)

    Science.gov (United States)

    Hockenberry, S L; Billingham, R E

    1987-12-01

    Two hundred twenty-five [corrected] respondents (109 [corrected] heterosexuals and 116 [corrected] homosexuals) completed a survey containing a 20-item Boyhood Gender Conformity Scale (BGCS). This scale was largely composed of edited and abridged gender items from Part A of Freund et al.'s Feminine Gender Identity Scale (FGIS-A) and Whitam's "childhood indicators." The combined scale was developed in an attempt to obtain a reliable, valid, and potent discriminating instrument for accurately classifying adult male respondents for sexual orientation on the basis of their reported boyhood gender conformity or nonconforming behavior and identity. In addition, 33% of these respondents were administered the original FGIS-A and Whitam inventory during a 2-week test-retest analysis conducted to determine the validity and reliability of the new instrument. All the original items significantly discriminated between heterosexual and homosexual respondents. From these a 13-item function and a 5-item function proved to be the most powerful discriminators between the two groups. Significant correlations between each of the three scales and a very high test-retest correlation coefficient supported the reliability and validity assumption for the BGCS. The conclusion was made that the five-item function (playing with boys, preferring [corrected] boys' games, imagining self as sports figure, reading adventure and sports stories, considered a "sissy") was the most potent and parsimonious discriminator among adult males for sexual orientation. It was similarly noted that the absence of masculine behaviors and traits appeared to be a more powerful predictor of later homosexual orientation than the traditionally feminine or cross-sexed traits and behaviors.

  2. A transcriptional switch underlies commitment to sexual development in malaria parasites.

    Science.gov (United States)

    Kafsack, Björn F C; Rovira-Graells, Núria; Clark, Taane G; Bancells, Cristina; Crowley, Valerie M; Campino, Susana G; Williams, April E; Drought, Laura G; Kwiatkowski, Dominic P; Baker, David A; Cortés, Alfred; Llinás, Manuel

    2014-03-13

    The life cycles of many parasites involve transitions between disparate host species, requiring these parasites to go through multiple developmental stages adapted to each of these specialized niches. Transmission of malaria parasites (Plasmodium spp.) from humans to the mosquito vector requires differentiation from asexual stages replicating within red blood cells into non-dividing male and female gametocytes. Although gametocytes were first described in 1880, our understanding of the molecular mechanisms involved in commitment to gametocyte formation is extremely limited, and disrupting this critical developmental transition remains a long-standing goal. Here we show that expression levels of the DNA-binding protein PfAP2-G correlate strongly with levels of gametocyte formation. Using independent forward and reverse genetics approaches, we demonstrate that PfAP2-G function is essential for parasite sexual differentiation. By combining genome-wide PfAP2-G cognate motif occurrence with global transcriptional changes resulting from PfAP2-G ablation, we identify early gametocyte genes as probable targets of PfAP2-G and show that their regulation by PfAP2-G is critical for their wild-type level expression. In the asexual blood-stage parasites pfap2-g appears to be among a set of epigenetically silenced loci prone to spontaneous activation. Stochastic activation presents a simple mechanism for a low baseline of gametocyte production. Overall, these findings identify PfAP2-G as a master regulator of sexual-stage development in malaria parasites and mark the first discovery of a transcriptional switch controlling a differentiation decision in protozoan parasites.

  3. Implementing international sexual counselling guidelines in hospital cardiac rehabilitation: development of the CHARMS intervention using the Behaviour Change Wheel.

    Science.gov (United States)

    Mc Sharry, J; Murphy, P J; Byrne, M

    2016-10-10

    Decreased sexual activity and sexual problems are common among people with cardiovascular disease, negatively impacting relationship satisfaction and quality of life. International guidelines recommend routine delivery of sexual counselling to cardiac patients. The Cardiac Health and Relationship Management and Sexuality (CHARMS) baseline study in Ireland found, similar to international findings, limited implementation of sexual counselling guidelines in practice. The aim of the current study was to develop the CHARMS multi-level intervention to increase delivery of sexual counselling by healthcare professionals. We describe the methods used to develop the CHARMS intervention following the three phases of the Behaviour Change Wheel approach: understand the behaviour, identify intervention options, and identify content and implementation options. Survey (n = 60) and focus group (n = 14) data from two previous studies exploring why sexual counselling is not currently being delivered were coded by two members of the research team to understand staff's capability, opportunity, and motivation to engage in the behaviour. All potentially relevant intervention functions to change behaviour were identified and the APEASE (affordability, practicability, effectiveness, acceptability, side effects and equity) criteria were used to select the most appropriate. The APEASE criteria were then used to choose between all behaviour change techniques (BCTs) potentially relevant to the identified functions, and these BCTs were translated into intervention content. The Template for Intervention Description and Replication (TIDieR) checklist was used to specify details of the intervention including the who, what, how and where of proposed intervention delivery. Providing sexual counselling group sessions by cardiac rehabilitation staff to patients during phase III cardiac rehabilitation was identified as the target behaviour. Education, enablement, modelling, persuasion and

  4. Growth with pollution: unsustainable development in Taiwan and its consequences.

    Science.gov (United States)

    Chi, C C

    1994-01-01

    Mutually supportive relationships between the Koumington (KMT) government and the private economic sector in Taiwan foster economic growth, which is incompatible with environmental protection. Environmental degradation in Taiwan is due almost exclusively to rapid economic growth; Taiwan should not be used as an example for developing countries. Taiwan's economic success was made possible because it did not have restrictions on pollution that its trading partners did. Air pollution reports in 1989 amounted to about 24 cases per day of appeals to environmental agencies country-wide. Major urban pollution sources include car, motorcycle, and industrial emissions. Acts passed in 1975 and 1982 have had little impact. Water pollution is caused by domestic sewage (25%), industrial waste water (54%), and domestic animal waste (21%). Untreated sewage in the water contributes to a high rate of hepatitis. Soil contamination is due to industrial development and agricultural intensification. Hazardous waste is dumped in the countryside; 3000 people in 1986 were poisoned by PCB-contaminated waste. Noise pollution standards are set at 60 decibels in residential areas and 65 decibels outside residential areas, but most find these levels too high. Industrial and toxic waste amounted in 1988 to 57,499 tons per day or 50% of Japan's volume. Waste is freely dumped into the air, water, and land. The food chain has been affected, and occupational diseases and cancer have doubled in 30 years. Deforestation on steep slopes contributes to serious soil erosion and fresh water resources problems. Economic growth maintains political legitimacy, sustains relationships between the government and the capitalist elites, and contributes to its monopoly of economic activities. The KMT government control of enterprises increased from 1 to 94 between the 1970s and 1986, while production by public enterprises declined over the same period. The Environmental Protection Agency has not been effective

  5. Development of "Long Live Love+," a School-Based Online Sexual Health Programme for Young Adults. An Intervention Mapping Approach

    Science.gov (United States)

    Mevissen, Fraukje E. F.; van Empelen, Pepijn; Watzeels, Anita; van Duin, Gee; Meijer, Suzanne; van Lieshout, Sanne; Kok, Gerjo

    2018-01-01

    This paper describes the development of a Dutch online programme called "Long Live Love+" focusing on positive, coercion-free relationships, contraception use, and the prevention of STIs, using the Intervention Mapping (IM) approach. All six steps of the approach were followed. Step 1 confirmed the need for a sexual health programme…

  6. Uncommonly Good: Exploring How Mass Media May Be a Positive Influence on Young Women's Sexual Health and Development

    Science.gov (United States)

    Ward, L. Monique; Day, Kyla M.; Epstein, Marina

    2006-01-01

    This chapter discusses several ways in which the media may serve as a positive force in young women's sexual health and development through the information and models they provide and the opportunities they offer for validation and self-expression. (Contains 1 table.)

  7. "It Could Affect You as a Person, Character-Wise": Promoting Character Development and Preventing Sexual Violence at West Point

    Science.gov (United States)

    Arbeit, Miriam R.

    2017-01-01

    The United States Military Academy at West Point develops cadets into "leaders of character" who will become Army officers. This focus on character presents an opportunity for the prevention of sexual violence through an emphasis on military values. Using constructivist grounded theory, this study examined how cadets experience their own…

  8. Relationships of Pubertal Development among Early Adolescents to Sexual and Nonsexual Risk Behaviors and Caregivers' Parenting Behaviors

    Science.gov (United States)

    Koo, Helen P.; Rose, Allison; Bhaskar, Brinda; Walker, Leslie R.

    2012-01-01

    Using a school-based sample of fifth graders (mean age = 10.38, SD = 0.66) and their parents (N = 408) from Washington, D.C., the authors examine associations of pubertal development with early adolescents' sexual and nonsexual risk behaviors and their caregivers' parenting behaviors and of these risk behaviors with parenting behaviors. Results…

  9. Is It Bullying or Sexual Harassment? Knowledge, Attitudes, and Professional Development Experiences of Middle School Staff

    Science.gov (United States)

    Charmaraman, Linda; Jones, Ashleigh E.; Stein, Nan; Espelage, Dorothy L.

    2013-01-01

    Background: This study fills a gap in the literature by examining how school staff members view bullying and sexual harassment and their role in preventing both. Given recent legislation, increasingly more attention is paid to bully prevention; however, student-on-student sexual harassment is less addressed. Methods: Four focus groups were…

  10. Development of a Clinical Instrument to Record Sexual Aggression in an Inpatient Psychiatric Setting

    Science.gov (United States)

    Jones, Nicole Tuomi; Sheitman, Brian; Hazelrigg, Mark; Carmel, Harold; Williams, Jim; Paesler, Betty

    2007-01-01

    While there are a number of instruments that assess historical factors related to sexual aggression for the purposes of risk assessment, there is a notable absence of measures that assess change in ongoing, sexually aggressive behaviours engaged in by people who reside in psychiatric hospitals. The purpose of this report is to describe the…

  11. Informing Sexual Health Intervention Development in India: Perspectives of Daughters, Mothers, and Service Providers in Mumbai

    Science.gov (United States)

    Adelson, Emiliya; Maitra, Shubhada; Nastasi, Bonnie K.

    2017-01-01

    In India, girls face many challenges that pose a threat to their sexual health and psychological well-being. The authors explore sexual health from the perspectives of adolescent girls, mothers of adolescent girls, and service providers. Focus groups and interview data were analyzed to understand the unique and shared perspectives of stakeholders.…

  12. Sexual identity development among gay, lesbian, and bisexual youths: consistency and change over time.

    Science.gov (United States)

    Rosario, Margaret; Schrimshaw, Eric W; Hunter, Joyce; Braun, Lisa

    2006-02-01

    A longitudinal report of 156 gay, lesbian, and bisexual youths examined changes in sexual identity over time. Fifty-seven percent of the youths remained consistently self-identified as gay/lesbian, 18% transited from bisexual to gay/lesbian, and 15% consistently identified as bisexual over time. Although youths who consistently identified as gay/lesbian did not differ from other youths on time since experiencing sexual developmental milestones, they reported current sexual orientation and sexual behaviors that were more same-sex centered and they scored higher on aspects of the identity integration process (e.g., more certain, comfortable, and accepting of their same-sex sexuality, more involved in gay-related social activities, more possessing of positive attitudes toward homosexuality, and more comfortable with others knowing about their sexuality) than youths who transited to a gay/lesbian identity and youths who consistently identified as bisexual. Contrary to the hypothesis that females are more sexually fluid than males, female youths were less likely to change identities than male youths. The finding that youths who transited to a gay/lesbian identity differed from consistently gay/lesbian youths suggests that identity integration continues after the adoption of a gay/lesbian sexual identity.

  13. The development of adolescents’ online sexual risk behavior and its relationship to negative online experiences

    NARCIS (Netherlands)

    Baumgartner, S.; Sumter, S.; Valkenburg, P.; Peter, J.

    2012-01-01

    The aim of this study was to investigate developmental pathways of online sexual risk behavior from early to late adolescence. Moreover, this study examined how these trajectories are related to negative online experiences, such as online sexual solicitation, online harassment, and online

  14. Ethical Parenting of Sexually Active Youth: Ensuring Safety While Enabling Development

    Science.gov (United States)

    Bay-Cheng, Laina Y.

    2013-01-01

    The protection of children from harm is commonly accepted as the cardinal duty of parents. In the USA, where young people's sexuality is often regarded with anxiety, attempts to restrict adolescent sexual behaviour are seen as ethically justified and even required of "good" parents. Running counter to popular anxiety surrounding young…

  15. Development of an Attachment-Informed Measure of Sexual Behavior in Late Adolescence

    Science.gov (United States)

    Szielasko, Alicia L.; Symons, Douglas K.; Price, E. Lisa

    2013-01-01

    There is considerable interest in relations between sexual behavior and romantic attachment styles in adolescence as attachment needs are increasingly met through intimate partners rather than parents. The objectives of this research were to organize a measure of sexual behavior within an attachment theory framework, and then show that this new…

  16. Men and Sexual Trauma

    Science.gov (United States)

    ... from the risk of sexual abuse. Early Child Development and Care, 110, 19-32. Carballo-Dieguez, A., & Dolezal, C. (1995). Association between history of childhood sexual abuse and adult HIV-risk ...

  17. Deposit growth and property development in coal-fired furnaces

    Energy Technology Data Exchange (ETDEWEB)

    Baxter, L. [Sandia National Lab., Livermore, CA (United States)

    1995-11-01

    The objectives of this research project are: (1) to provide a self-consistent database of simultaneously measured, time-resolved ash deposit properties in well-controlled and well-defined environments and (2) to provide analytical expressions that relate deposit composition and structure to deposit properties of immediate relevance to PETC`s Combustion 2000 program. This project is distinguished from related work being done elsewhere by: (1) the development and deployment of in-situ diagnostics to monitor deposit properties, including heat transfer coefficients, porosity, emissivity, tenacity, strength, density, and viscosity; (2) the time resolution of such properties during deposit growth; (3) simultaneous measurement of structural and composition properties; (4) development of algorithms from a self-consistent, simultaneously measured database that includes the interdependence of properties; and (5) application of the results to technologically relevant environments such as those being planned under Combustion 2000 program. Work completed during FY94 emphasized diagnostic development. During FY95, this development work will be completed and we will emphasize application of the diagnostics to meet the other project objectives. Included in this work are the development and application of two in-situ, real-time diagnostic systems for monitoring the properties of inorganic materials on Heat transfer surfaces and in the gas-phase during controlled combustion of selected coal samples in Sandia`s Multifuel Combustor (MFC). Also, several diagnostics are being incorporated into the MFC that will eventually be used to characterize ash deposit properties.

  18. Report of the Phase 1 of the Validation of the Fish Sexual Development Test for the Detection of Endocrine Active Substances

    DEFF Research Database (Denmark)

    Holbech, Henrik; Kinnberg, Karin Lund; Petersen, Gitte

    This document presents the validation report (phase 1) of the Fish Sexual Development Test (FSDT). The FSDT covers a life-stage where sexual development is particularly sensitive to perturbation caused by endocrine active chemicals. The chemical exposure lasts for about 60 days, at the end of which...

  19. 'Sexual violence is not good for our country’s development' : Students’ interpretations of sexual violence in a secondary school in Addis Ababa, Ethiopia

    NARCIS (Netherlands)

    Le Mat, M.L.J.

    2016-01-01

    It has been increasingly recognised that sexual violence in schools is one of the major concerns with regard to promoting sexual and reproductive health and rights. This paper examines how boys and girls define, experience, and interpret sexual violence in a secondary school in Addis Ababa,

  20. "Sexual Violence Is Not Good for Our Country's Development". Students' Interpretations of Sexual Violence in a Secondary School in Addis Ababa, Ethiopia

    Science.gov (United States)

    Le Mat, Marielle L. J.

    2016-01-01

    It has been increasingly recognised that sexual violence in schools is one of the major concerns with regard to promoting sexual and reproductive health and rights. This paper examines how boys and girls define, experience, and interpret sexual violence in a secondary school in Addis Ababa, Ethiopia, and considers from their perspectives, how…

  1. Biology of insulin-like growth factors in development.

    Science.gov (United States)

    Dupont, Joëlle; Holzenberger, Martin

    2003-11-01

    Insulin-like growth factors (IGFs) provide essential signals for the control of embryonic and postnatal development in vertebrate species. In mammals, IGFs act through and are regulated by a system of receptors, binding proteins, and related proteases. In each of the many tissues dependent on this family of growth factors, this system generates a complex interaction specific to the tissue concerned. Studies carried out over the last decade, mostly with transgenic and gene knockout mouse models, have demonstrated considerable variety in the cell type-specific and developmental stage-specific functions of IGF signals. Brain, muscle, bone, cartilage, pancreas, ovary, skin, and fat tissue have been identified as major in vivo targets for IGFs. Concentrating on several of these organ systems, we review here phenotypic analyses of mice with genetically modified IGF systems. Much progress has also been made in understanding the specific intracellular signaling cascades initiated by the binding of circulating IGFs to their cognate receptor. We also summarize the most relevant aspects of this research. Considerable efforts are currently focused on deciphering the functional specificities of intracellular pathways, particularly the molecular mechanisms by which cells distinguish growth-stimulating insulin-like signals from metabolic insulin signals. Finally, there is a growing body of evidence implicating IGF signaling in lifespan control, and it has recently been shown that this function has been conserved throughout evolution. Very rapid progress in this domain seems to indicate that longevity may be subject to IGF-dependent neuroendocrine regulation and that certain periods of the life cycle may be particularly important in the determination of individual lifespan. Copyright 2003 Wiley-Liss, Inc.

  2. Expression of PITX2 homeodomain transcription factor during rat gonadal development in a sexually dimorphic manner.

    Science.gov (United States)

    Nandi, Shyam Sundar; Ghosh, Pamela; Roy, Sib Sankar

    2011-01-01

    PITX2, a multifunctional Paired-like homeodomain transcription factor, plays obligatory role during development of organs like heart, brain and pituitary. It regulates differentiation of vascular smooth muscle cells and hematopoietic stem cells. Although we earlier reported the Pitx2/PITX2 expression in gonad, but the expression pattern of its different isoforms in mammalian gonads especially during development is still not known. As PITX2 participates in the development of multiple organs and different homeobox genes have been shown to control gonadal functions, we wanted to investigate the role of PITX2 in gonadal development and its function. The objective of our study was to know the expression profile of different Pitx2/PITX2 isoforms and its localization throughout the development of gonads. Here we show the temporal and spatial expression pattern of Pitx2/PITX2 and its localization throughout the embryonic and postnatal stages of rat gonads. Pitx2/PITX2 expression profile reveals the differential and dimorphic expression pattern of its two isoforms PITX2B2 and-Cβ throughout the embryonic development stages and also in the postnatal stages, where it becomes more prominent. This is the first report where PITX2 homeodomain transcription factor shows isoform-specific sexually dimorphic expression. In addition, PITX2 localization was found in the embryonic ovarian primordial germ cell clusters and germ cells inside the testicular cords and also in somatic cells. In adults, ovarian granulosa and theca cells as well as germ cells inside the seminiferous tubules in testis express PITX2. All the evidences suggest that the differential expression of PITX2 might be associated with sex-specific embryonic and postnatal gonadal development and the physiological processes. Copyright © 2011 S. Karger AG, Basel.

  3. In utero exposure to chloroquine alters sexual development in the male fetal rat

    International Nuclear Information System (INIS)

    Clewell, Rebecca A.; Pluta, Linda; Thomas, Russell S.; Andersen, Melvin E.

    2009-01-01

    Chloroquine (CQ), a drug that has been used extensively for the prevention and treatment of malaria, is currently considered safe for use during pregnancy. However, CQ has been shown to disrupt steroid homeostasis in adult rats and similar compounds, such as quinacrine, inhibit steroid production in the Leydig cell in vitro. To explore the effect of in utero CQ exposure on fetal male sexual development, pregnant Sprague-Dawley rats were given a daily dose of either water or chloroquine diphosphate from GD 16-18 by oral gavage. Chloroquine was administered as 200 mg/kg CQ base on GD 16, followed by two maintenance doses of 100 mg/kg CQ base on GD 16 and 18. Three days of CQ treatment resulted in reduced maternal and fetal weight on GD 19 and increased necrosis and steatosis in the maternal liver. Fetal livers also displayed mild lipid accumulation. Maternal serum progesterone was increased after CQ administration. Fetal testes testosterone, however, was significantly decreased. Examination of the fetal testes revealed significant alterations in vascularization and seminiferous tubule development after short-term CQ treatment. Anogenital distance was not altered. Microarray and RT-PCR showed down-regulation of several genes associated with cholesterol transport and steroid synthesis in the fetal testes. This study indicates that CQ inhibits testosterone synthesis and normal testis development in the rat fetus at human relevant doses.

  4. Development of radiation utilization for economic growth in China

    International Nuclear Information System (INIS)

    Lu Yanxiao

    1994-01-01

    The program of radiation utilization in China was initiated with the development of nuclear industry in the late 1950s. From then on, the establishment of relatively comprehensive nuclear industrial system and a fair number of talent technical personnel have laid the foundation for radiation utilization in industry, agriculture, medicine and so on. Radioisotopes and radiation become one of the most effective means for acquiring data and information and changing material properties in modern techniques. They are, in many respects, unique and cannot replaced by other techniques. In recent years the considerable progress in the development, commercialization and large-scale utilization of radioisotopes and radiation has been creating economic and social benefits for Chinese modernization. The applications in agriculture have mainly embodied in mutation breeding of crops and so on through radiation or in combination with other methods to provide excellent mutant varieties. The important applications in medicine are the medical diagnosis with radioimmunoassay (RIA) and radiopharmaceutical imaging, and cancer therapy with radioisotopes and electron beam. Well-established methods have bee offered for routine clinic applications to help to heal the patients and rescue the lives. The industrial applications are of key importance in economic growth in China. In fact, radiation processing and nucleonic control systems (NCS) for industrial utilization are very useful to technological transformation of Chinese traditional industries. The radiation utilization in industries can be emerging as new high-tech industries. A fuller exploitation of radiation utilization is expected to meet the requirements of high growth of national economy and to bridge the gap between China and the developed countries in the world in nuclear application. (author)

  5. Regional growth and atlasing of the developing human brain

    Science.gov (United States)

    Makropoulos, Antonios; Aljabar, Paul; Wright, Robert; Hüning, Britta; Merchant, Nazakat; Arichi, Tomoki; Tusor, Nora; Hajnal, Joseph V.; Edwards, A. David; Counsell, Serena J.; Rueckert, Daniel

    2016-01-01

    Detailed morphometric analysis of the neonatal brain is required to characterise brain development and define neuroimaging biomarkers related to impaired brain growth. Accurate automatic segmentation of neonatal brain MRI is a prerequisite to analyse large datasets. We have previously presented an accurate and robust automatic segmentation technique for parcellating the neonatal brain into multiple cortical and subcortical regions. In this study, we further extend our segmentation method to detect cortical sulci and provide a detailed delineation of the cortical ribbon. These detailed segmentations are used to build a 4-dimensional spatio-temporal structural atlas of the brain for 82 cortical and subcortical structures throughout this developmental period. We employ the algorithm to segment an extensive database of 420 MR images of the developing brain, from 27 to 45 weeks post-menstrual age at imaging. Regional volumetric and cortical surface measurements are derived and used to investigate brain growth and development during this critical period and to assess the impact of immaturity at birth. Whole brain volume, the absolute volume of all structures studied, cortical curvature and cortical surface area increased with increasing age at scan. Relative volumes of cortical grey matter, cerebellum and cerebrospinal fluid increased with age at scan, while relative volumes of white matter, ventricles, brainstem and basal ganglia and thalami decreased. Preterm infants at term had smaller whole brain volumes, reduced regional white matter and cortical and subcortical grey matter volumes, and reduced cortical surface area compared with term born controls, while ventricular volume was greater in the preterm group. Increasing prematurity at birth was associated with a reduction in total and regional white matter, cortical and subcortical grey matter volume, an increase in ventricular volume, and reduced cortical surface area. PMID:26499811

  6. You and Me and Human Sexuality: A Student Booklet Written for Deaf Adolescents.

    Science.gov (United States)

    Texas School for the Deaf, Austin.

    This student booklet, designed to teach deaf adolescents about human sexuality, is written for students with a second- to fourth-grade reading level. Topics include: (1) relationships; (2) adolescent growth and development; (3) female and male anatomy; (4) conception, fetal development, and birth; (5) contraception; and (6) sexual intercourse and…

  7. What couples say about their recovery of sexual intimacy after prostatectomy: toward the development of a conceptual model of couples’ sexual recovery after surgery for prostate cancer

    Science.gov (United States)

    Wittmann, Daniela; Carolan, Marsha; Given, Barbara; Skolarus, Ted A.; Crossley, Heather; An, Lawrence; Palapattu, Ganesh; Clark, Patricia; Montie, James E.

    2015-01-01

    Introduction Interventions designed to help couples recover sexual intimacy after prostatectomy have not been guided by a comprehensive conceptual model. Aim We examined a proposed biopsychosocial conceptual model of couples’ sexual recovery that included functional, psychological and relational aspects of sexuality, surgery-related sexual losses, and grief and mourning as recovery process. Methods We interviewed twenty couples pre-operatively and 3-months post-operatively. between 2010 and 2012. Interviews were analyzed with Analytic Induction qualitative methodology, using NVivo software. Paired t-tests described functional assessment data. Study findings led to a revised conceptual model. Main Outcome Measures Couples’ experiences were assessed through semi-structured interviews; male participants’ sexual function was assessed with the Expanded Prostate Cancer Index Composite and female participants’ sexual function with the Female Sexual Function Index. Results Pre-operatively, 30% of men had erectile dysfunction (ED), 84% of partners were post-menopausal. All valued sexual recovery, but worried about cancer spread and surgery side-effects. Faith in themselves and their surgeons led 90% of couples to overestimate erectile recovery. Post-operatively, most men had ED and lost confidence. Couples’ sexual activity decreased. Couples reported feeling loss and grief: cancer diagnosis was the first loss, followed by surgery-related sexual losses. Couples’ engagement in intentional sex, patients’ acceptance of erectile aids and partners’ interest in sex aided the recovery of couples’ sexual intimacy recovery. Unselfconscious sex, not return to erectile function baseline, was seen as the endpoint. Survey findings documented participants’ sexual function losses, confirming qualitative findings. Conclusions Couples’ sexual recovery requires addressing sexual function, feelings about losses and relationship simultaneously. Peri-operative education

  8. Indicators of physical and sexual development of adolescent boys, depending on the functional state of the thyroid gland

    Directory of Open Access Journals (Sweden)

    K. G. Kamalov

    2015-01-01

    Full Text Available Republic of Dagestan is a region with medium and severe iodine deficiency, which is associated with the development of endemic goiter and subclinical hypothyroidism. Children with goiter with or without it with SG had the worst indicators of physical, psychological and sexual development, tended to chronic somatic pathology.Objective. To examine the connection between the elevated TSH level with indicators of physical and sexual health of boys.Material and methodThere were examined 297 adolescents aged 11-13 years (76 persons in the beginning of puberty and 14-17 years (221 people in the middle and the end of puberty. The anthropometric studies of height, weight were conducted, body mass index BMI was calculated, the degree of sexual development: R - pubic body hair, G-degree sexual development, testicular volume by Prader and the size of the penis, index of virilization, level tireotroponogo hormone (TSH were assessed.Results showed that physical development of boys already in the early stages of dysfunction of the thyroid gland tends to lag behind. This is more evident in the mid to completion of puberty (boys and adolescents 14-17 years of age, secondary sexual characteristics in boys 11-13 years more marked in those with a TSH level of 0.5 to 2.6 IU/l compared with peers with TSH levels from 4.2 to 10.0 IU/l In the subgroup of 14-17 year old boys and teenagers, there is a tendency to the phenomenon of "macroorchidism" beginning at the stage of subclinical hypothyroidism.

  9. Twenty years after International Conference on Population and Development: where are we with adolescent sexual and reproductive health and rights?

    Science.gov (United States)

    Chandra-Mouli, Venkatraman; Svanemyr, Joar; Amin, Avni; Fogstad, Helga; Say, Lale; Girard, Françoise; Temmerman, Marleen

    2015-01-01

    The International Conference on Population and Development in Cairo in 1994 laid out a bold, clear, and comprehensive definition of reproductive health and called for nations to meet the educational and service needs of adolescents to enable them to deal in a positive and responsible way with their sexuality. In the context of the ongoing review of the International Conference on Population and Development Programme of Action and the considerations for a post-2015 development agenda, this article summarizes the findings of the articles presented in this volume and identifies key challenges and critical answers that need to be tackled in addressing adolescent sexual and reproductive health and rights. The key recommendations are to link the provision of sexuality education and sexual and reproductive health (SRH) services; build awareness, acceptance, and support for youth-friendly SRH education and services; address gender inequality in terms of beliefs, attitudes, and norms; and target the early adolescent period (10-14 years). The many knowledge gaps, however, point to the pressing need for further research on how to best design effective adolescent SRH intervention packages and how best to deliver them. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  10. Developing a dynamic growth model for teak plantations in India

    Directory of Open Access Journals (Sweden)

    Vindhya Prasad Tewari

    2014-05-01

    Full Text Available Background Tectona grandis (teak is one of the most important tropical timber speciesoccurring naturally in India. Appropriate growth models, based on advanced modeling techniques,are not available but are necessary for the successful management of teak stands in the country.Long-term forest planning requires mathematical models, and the principles of Dynamical SystemTheory provide a solid foundation for these. Methods The state-space approach makes it possible to accommodate disturbances and avarying environment. In this paper, an attempt has been made to develop a dynamic growthmodel based on the limited data, consisting of three annual measurements, collected from 22 teak sample plots in Karnataka, Southern India. Results A biologically consistent whole-stand growth model has been presented which uses thestate-space approach for modelling rates of change of three state-variables viz., dominant height,stems per hectare and stand basal area. Moreover, the model includes a stand volume equationas an output function to estimate this variable at any point in time. Transition functions werefitted separately and simultaneously. Moreover, a continuous autoregressive error structure isalso included in the modelling process. For fitting volume equation, generalized method of moments was used to get efficient parameter estimates under heteroscedastic conditions. Conclusions A simple model containing few free parameters performed well and is particularlywell suited to situations where available data is scarce.

  11. Growth patterns in children with intrauterine growth retardation and their correlation to neurocognitive development.

    Science.gov (United States)

    Fattal-Valevski, Aviva; Toledano-Alhadef, Hagit; Leitner, Yael; Geva, Ronny; Eshel, Rina; Harel, Shaul

    2009-07-01

    The relationship between somatic growth and neurocognitive outcome was studied in a cohort of 136 children with intrauterine growth retardation. The children were followed up from birth to 9 to 10 years of age by annual measurements of growth parameters, neurodevelopmental evaluations, and IQ. The rate of catch-up for height between 1 and 2 years of age was significantly higher than the catch-up for weight (P importance for prediction of subsequent neurodevelopmental outcome in children with intrauterine growth retardation.

  12. Fetal, neonatal, infant, and child international growth standards: an unprecedented opportunity for an integrated approach to assess growth and development.

    Science.gov (United States)

    Garza, Cutberto

    2015-07-01

    The recent publication of fetal growth and gestational age-specific growth standards by the International Fetal and Newborn Growth Consortium for the 21st Century Project and the previous publication by the WHO of infant and young child growth standards based on the WHO Multicentre Growth Reference Study enable evaluations of growth from ∼9 wk gestation to 5 y. The most important features of these projects are the prescriptive approach used for subject selection and the rigorous testing of the assertion that growth is very similar among geographically and ethnically diverse nonisolated populations when health, nutrition, and other care needs are met and the environment imposes minimal constraints on growth. Both studies documented that with adequate controls, the principal source of variability in growth during gestation and early childhood resides among individuals. Study sites contributed much less to observed variability. The agreement between anthropometric measurements common to both studies also is noteworthy. Jointly, these studies provide for the first time, to my knowledge, a conceptually consistent basis for worldwide and localized assessments and comparisons of growth performance in early life. This is an important contribution to improving the health care of children across key periods of growth and development, especially given the appropriate interest in pursuing "optimal" health in the "first 1000 d," i.e., the period covering fertilization/implantation, gestation, and postnatal life to 2 y of age. © 2015 American Society for Nutrition.

  13. Effects of polymeric carbohydrates on growth and development in pigs

    DEFF Research Database (Denmark)

    Knudsen, Knud Erik Bach

    2011-01-01

    Polymeric carbohydrates, starch and nonstarch polysaccharides (NSP), quantitatively represent the largest portion of the diets for pigs and are, therefore, the largest energy contributor. The 2 types of polysaccharides, however, have different fates and functions in the gastrointestinal tract...... carbohydrates influence growth and development through different mechanisms. First, the proportion of starch to NSP plays an important role for the content of available energy (i.e., DE, ME, and NE); available energy relative to protein is crucial for performance and carcass quality. Second, the proportion...... of starch to NSP will influence rate and type of metabolites (i.e., glucose vs. SCFA) deriving from carbohydrate assimilation. Third and finally, the type of starch (i.e., types A, B, and C) and soluble NSP will influence the release of insulin, the hormone that facilitates nutrient uptake by tissues...

  14. Relationships among sexual self-concept, sexual risk cognition and sexual communication in adolescents: a structural equation model.

    Science.gov (United States)

    Lou, Jiunn-Horng; Chen, Sheng-Hwang; Li, Ren-Hau; Yu, Hsing-Yi

    2011-06-01

    The purpose of this study was to test a model of sexual self-concept and sexual risk cognition affecting sexual communication in Taiwanese adolescents. Parent-adolescent sexual communication has been shown to influence adolescent sexual behaviour. Self-concept is an important predictor of human behaviour, especially sexual behaviour. Few researchers have assessed sexual self-concept in adolescents, despite its clear relevance to understanding adolescent sexual behaviour. A cross-sectional survey with convenience sampling was used in this study. In 2009, data were collected by questionnaire from 748 adolescent students at a junior college in Taiwan. The results revealed that the postulated model fits the data from this study well. Sexual self-concept significantly predicts sexual risk cognition and sexual communication. Sexual risk cognition significantly predicts sexual communication and has an intervening effect on the relationship between sexual self-concept and sexual communication. Sexual risk cognition is important in explaining sexuality in adolescents. Sexual self-concept has both direct and indirect effects on sexual communication. Our findings provide concrete directions for school educators in developing sexual health programmes to increase adolescent sexual self-concept and sexual communication with their parents. Future sexual health programmes about sexual self-concept and sexual risk cognition must add for increasing adolescent's sexual communication with their parents. © 2010 Blackwell Publishing Ltd.

  15. foreign direct investment and economic growth in developing ...

    African Journals Online (AJOL)

    Prof

    matters for its effect on economic growth. Few sectors reflected a positive impact of. FDI and one sector even showed a robust negative impact of FDI on economic growth. Vijayakumar and Sridharan, (2010) study the causal relationship between. Foreign Direct Investment and Growth in the BRICS countries (Brazil, Russia, ...

  16. Children victims of sexual abuse: some aspects observed in their development

    OpenAIRE

    Amazarray, Mayte Raya; Koller, Silvia Helena

    1998-01-01

    O abuso sexual de crianças é um dos tipos de maus-tratos mais freqüentes, apresentando implicações médicas, legais e psicossociais. Essa revisão da literatura aponta para algumas conseqüências do abuso sexual infantil, com o objetivo de entender o seu impacto no desenvolvimento da criança. Os efeitos prejudiciais do abuso sexual, a reação negativa da família e o despreparo dos profissionais constituem um potencial gerador de danos psicológicos para a criança. Devido a esses fatores, as crianç...

  17. Brief Intervention for Truant Youth Sexual Risk Behavior and Alcohol Use: A Parallel Process Growth Model Analysis

    Science.gov (United States)

    Dembo, Richard; Briones-Robinson, Rhissa; Ungaro, Rocio; Barrett, Kimberly; Gulledge, Laura; Winters, Ken C.; Belenko, Steven; Karas, Lora M.; Wareham, Jennifer

    2014-01-01

    Truant youths frequently experience family problems, emotional/psychological issues, substance misuse, and delinquency. They are likely engaging in alcohol use and sexual risk behavior at a higher rate than the general youth population. Early intervention services would benefit them, their families, and society. We present interim findings from an…

  18. Sexually different morphological, physiological and molecular responses of Fraxinus mandshurica flowers to floral development and chilling stress.

    Science.gov (United States)

    Zhu, Zhu; Qi, Fenghui; Yan, Chaofu; Zhan, Yaguang

    2016-02-01

    Fraxinus mandshurica is considered a dioecious hardwood, and the temporal separation of the maturation of the male and female flowers is one reason that F. mandshurica has become an endangered species in China. Rainfall and low temperature influence pollen formation and dispersal and the blooming of female flowers. Therefore, low fertilization efficiency strongly influences the population of F. mandshurica. Nevertheless, few studies have investigated the sex-specific morphological, physiological and molecular differentiation of F. mandshurica during flowering and its responses to low temperature. In this study, we investigated the sexual differences in the morphological, physiological, and biochemical parameters of F. mandshurica during flowering and determined the physiological and biochemical parameters and expression levels of related genes in response to low-temperature stress induced by exposure to 4 °C (chilling stress) during pollen dispersal and fertilization. Our study supports the hypothesis that male flowers suffer more severe injuries while female flowers are more adaptable to environmental stress during flower development in F. mandshurica. The results showed higher physiological and biochemical levels of malondialdehyde, proline, and soluble sugar, as well as the expression of genes involved in calcium signaling, cold shock and DNA methylation in male flowers compared with female flowers, which suggested that male flowers suffer from more serious peroxidation than female flowers. In contrast, higher antioxidant capacity and FmaCAT expression were detected in female flowers, providing preliminary evidence that male flowers rapidly fade after pollination and further demonstrating that female flowers need a much stronger antioxidant enzyme system to maintain embryonic growth. Most peaks related to physiological and molecular responses were observed at 2-4 h and 8-10 h of exposure to chilling stress in the female and male flowers, respectively

  19. Effect of Simulated Microgravity on Sexual Development of Male Japanese Quail

    Directory of Open Access Journals (Sweden)

    Peter Škrobánek

    2009-01-01

    Full Text Available Hypodynamia can be used to simulate weightlessness in laboratory conditions. The objective of our study was to investigate the effects of chronic hypodynamia on the growth and development of the testes and cloacal gland, and plasma testosterone concentration in Japanese quail. The testis weight in males reared under hypodynamia was significantly lower compared to agematched control between 21 and 63 days of age (P P P P < 0.05, with the exception of day 56. These results provide further evidence that although hypodynamia negatively affects the examined variables, the male Japanese quail is able to develop normally under conditions of simulated weightlessness.

  20. Influence of a past history of Gambian sleeping sickness on physical growth, sexual maturity and academic performance of children in Fontem, Cameroon.

    Science.gov (United States)

    Aroke, A H; Asonganyi, T; Mbonda, E

    1998-12-01

    Little has been published on the long-term complications of Gambian sleeping sickness (GSS) following treatment. A case-control study to compare physical growth, sexual maturity and academic performance of children with and without a past history of GSS was therefore conducted. The study took place over a period of 6 months, in the 10 villages of the Fontem GSS focus, which is known to be very endemic for the disease. Overall, 100 young subjects (aged 6-20 years) with a past history of GSS were pair-matched for age (+/- 5 months), sex, place of residence, and socio-economic and cultural backgrounds with 100 other, control subjects who had no history of GSS and who were sero-negative for GSS when checked with a card agglutination test (Testryp-CATT). On average, the cases weighed 4.25 kg less, were 3 cm shorter and had 1.15-cm smaller mid-upper-arm circumferences than the controls (P growth and sexual maturity.