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Sample records for group differences suggest

  1. Similarities in the structure of the transcriptional repressor AmtR in two different space groups suggest a model for the interaction with GlnK.

    Science.gov (United States)

    Sevvana, Madhumati; Hasselt, Kristin; Grau, Florian C; Burkovski, Andreas; Muller, Yves A

    2017-03-01

    AmtR belongs to the TetR family of transcription regulators and is a global nitrogen regulator that is induced under nitrogen-starvation conditions in Corynebacterium glutamicum. AmtR regulates the expression of transporters and enzymes for the assimilation of ammonium and alternative nitrogen sources, for example urea, amino acids etc. The recognition of operator DNA by homodimeric AmtR is not regulated by small-molecule effectors as in other TetR-family members but by a trimeric adenylylated PII-type signal transduction protein named GlnK. The crystal structure of ligand-free AmtR (AmtRorth) has been solved at a resolution of 2.1 Å in space group P21212. Comparison of its quaternary assembly with the previously solved native AmtR structure (PDB entry 5dy1) in a trigonal crystal system (AmtRtri) not only shows how a solvent-content reduction triggers a space-group switch but also suggests a model for how dimeric AmtR might stoichiometrically interact with trimeric adenylylated GlnK.

  2. Managing HCV infection in pediatric age group: Suggested recommendations

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    Danish Fazal

    2010-01-01

    Full Text Available Hepatitis C virus (HCV infection in children is different from the adult infection in many ways, like natural course of the disease; duration, therapeutic response and side effects profile of the drug therapy; and prognosis. Special considerations include consideration on what could be the appropriate time to investigate a suspected child, when to institute drug therapy and how to prevent vertical transmission. Although over the past one decade many landmark studies have greatly increased our insight on this subject, yet we are far from developing a consensus statement. In this article, a concise yet comprehensive review of HCV infection in children - diagnosis and treatment - is given, followed by suggested recommendations at the end. It is hoped that these recommendations will help develop local guidelines on this subject.

  3. Quantitative Approaches to Group Research: Suggestions for Best Practices

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    McCarthy, Christopher J.; Whittaker, Tiffany A.; Boyle, Lauren H.; Eyal, Maytal

    2017-01-01

    Rigorous scholarship is essential to the continued growth of group work, yet the unique nature of this counseling specialty poses challenges for quantitative researchers. The purpose of this proposal is to overview unique challenges to quantitative research with groups in the counseling field, including difficulty in obtaining large sample sizes…

  4. Quantitative Approaches to Group Research: Suggestions for Best Practices

    Science.gov (United States)

    McCarthy, Christopher J.; Whittaker, Tiffany A.; Boyle, Lauren H.; Eyal, Maytal

    2017-01-01

    Rigorous scholarship is essential to the continued growth of group work, yet the unique nature of this counseling specialty poses challenges for quantitative researchers. The purpose of this proposal is to overview unique challenges to quantitative research with groups in the counseling field, including difficulty in obtaining large sample sizes…

  5. The group discussion effect: integrative processes and suggestions for implementation.

    Science.gov (United States)

    Meleady, Rose; Hopthrow, Tim; Crisp, Richard J

    2013-02-01

    One of the most consistent findings in experimental social dilemmas research is the positive effect group discussion has on cooperative behavior. At a time when cooperation and consensus is critical to tackle global problems, ranging from debt to deforestation, understanding the dynamics of group discussion is a pressing need. Unfortunately, research investigating the underlying processes and implementation of the effect has been inconclusive. The authors present a critical review of existing explanations and integrate these perspectives into a single process model of group discussion, providing a more complete theoretical picture of how interrelated factors combine to facilitate discussion-induced cooperation. On the basis of this theoretical analysis, they consider complimentary approaches to the indirect and feasible implementation of group discussion. They argue that such strategies may overcome the barriers to direct discussion observed across a range of groups and organizations.

  6. Teaching English Pronunciation to Large Groups of Students: Some Suggestions.

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    Makarova, Veronika

    Problems in teaching English pronunciation to large groups of university students in Japan are discussed, and some solutions are offered. Pronunciation instruction requires close individual interaction between teacher and student, difficult if not impossible to achieve in a typical Japanese university classroom. However, it is possible to get…

  7. Using suggestion to model different types of automatic writing.

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    Walsh, E; Mehta, M A; Oakley, D A; Guilmette, D N; Gabay, A; Halligan, P W; Deeley, Q

    2014-05-01

    Our sense of self includes awareness of our thoughts and movements, and our control over them. This feeling can be altered or lost in neuropsychiatric disorders as well as in phenomena such as "automatic writing" whereby writing is attributed to an external source. Here, we employed suggestion in highly hypnotically suggestible participants to model various experiences of automatic writing during a sentence completion task. Results showed that the induction of hypnosis, without additional suggestion, was associated with a small but significant reduction of control, ownership, and awareness for writing. Targeted suggestions produced a double dissociation between thought and movement components of writing, for both feelings of control and ownership, and additionally, reduced awareness of writing. Overall, suggestion produced selective alterations in the control, ownership, and awareness of thought and motor components of writing, thus enabling key aspects of automatic writing, observed across different clinical and cultural settings, to be modelled.

  8. Retrohoming of a Mobile Group II Intron in Human Cells Suggests How Eukaryotes Limit Group II Intron Proliferation.

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    David M Truong

    2015-08-01

    Full Text Available Mobile bacterial group II introns are evolutionary ancestors of spliceosomal introns and retroelements in eukaryotes. They consist of an autocatalytic intron RNA (a "ribozyme" and an intron-encoded reverse transcriptase, which function together to promote intron integration into new DNA sites by a mechanism termed "retrohoming". Although mobile group II introns splice and retrohome efficiently in bacteria, all examined thus far function inefficiently in eukaryotes, where their ribozyme activity is limited by low Mg2+ concentrations, and intron-containing transcripts are subject to nonsense-mediated decay (NMD and translational repression. Here, by using RNA polymerase II to express a humanized group II intron reverse transcriptase and T7 RNA polymerase to express intron transcripts resistant to NMD, we find that simply supplementing culture medium with Mg2+ induces the Lactococcus lactis Ll.LtrB intron to retrohome into plasmid and chromosomal sites, the latter at frequencies up to ~0.1%, in viable HEK-293 cells. Surprisingly, under these conditions, the Ll.LtrB intron reverse transcriptase is required for retrohoming but not for RNA splicing as in bacteria. By using a genetic assay for in vivo selections combined with deep sequencing, we identified intron RNA mutations that enhance retrohoming in human cells, but <4-fold and not without added Mg2+. Further, the selected mutations lie outside the ribozyme catalytic core, which appears not readily modified to function efficiently at low Mg2+ concentrations. Our results reveal differences between group II intron retrohoming in human cells and bacteria and suggest constraints on critical nucleotide residues of the ribozyme core that limit how much group II intron retrohoming in eukaryotes can be enhanced. These findings have implications for group II intron use for gene targeting in eukaryotes and suggest how differences in intracellular Mg2+ concentrations between bacteria and eukarya may have

  9. Strategies for Sharing Scientific Research on Sea Level Rise: Suggestions from Stakeholder Focus Groups

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    DeLorme, D.; Hagen, S. C.; Stephens, S. H.

    2013-12-01

    This presentation reports results of focus groups with coastal resource managers on suggestions for effectively sharing sea level rise (SLR) scientific research with the public and other target audiences. The focus groups were conducted during three annual stakeholder workshops as an important and innovative component of an ongoing five-year multi-disciplinary NOAA-funded project, Ecological Effects of Sea Level Rise in the Northern Gulf of Mexico (EESLR-NGOM). The EESLR-NGOM project is assessing SLR risks to the natural and built environment along the Mississippi, Alabama, and Florida Panhandle coasts. The purpose was to engage stakeholders (e.g., coastal resource managers) in helping target, translate, and tailor the EESLR-NGOM project's scientific findings and emerging products so they are readily accessible, understandable, and useful. The focus groups provided insight into stakeholders' SLR informational and operational needs, solicited input on the project's products, and gathered suggestions for public communication and outreach. A total of three ninety-minute focus groups of between eight and thirteen participants each were conducted at annual workshops in Alabama, Florida, and Mississippi. The moderator asked a series of open-ended questions about SLR-related topics using an interview guide and encouraged participant interaction. All focus group audio-recordings were transcribed, and analyzed by carefully reading the 102 total pages of transcript data and identifying patterns and themes. Participants thought outreach about SLR impact and the EESLR-NGOM project scientific research/products was vital and acknowledged various communication challenges and opportunities. They identified three target audiences (local officials, general public, coastal resource managers themselves) that likely require different educational efforts and tools. Participants felt confident the EESLR-NGOM project products will benefit their resource planning and decision making and

  10. Heart rate variability in subjects with different hypnotic susceptibility receiving nociceptive stimulation and suggestions of analgesia.

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    Balocchi, R; Varanini, M; Menicucci, D; Santarcangelo, E L; Migliorini, S; Fontani, G; Carli, G

    2005-01-01

    The aim of the present study was to investigate the possible hypnotizability-related modulation of heart activity during nociceptive stimulation (pressor pain) and during nociceptive stimulation associated with the suggestion of analgesia in not hypnotized healthy individuals with a high (Highs) and a low (Lows) hypnotic susceptibility. ECG and respirogram were recorded. Standard time and frequency domain indexes were evaluated, together with the sd1 and sd2 values of the Poincaré plot over the RR series. Results showed self reports of analgesia in Highs and a significant increase of the respiratory frequency during stimulation in both groups. Very few significant differences between groups and among conditions were detected for mean RR and heart rate variability (HRV) through spectral analysis. and through the Poincaré indexes evaluation. On the contrary, a promising approach seems to be the study of the correlations among standard and Poincaré variables. In particular, different changes in (or even lost of) correlations were enlightened in Highs and Lows, suggesting a different modulation of RR in the two groups, probably due to the very low frequency components of HRV. Different roles of sympathetic and parasympathetic activities during stimulation can be suggested.

  11. Individual Differences in the Rubber Hand Illusion Are Related to Sensory Suggestibility.

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    Marotta, Angela; Tinazzi, Michele; Cavedini, Clelia; Zampini, Massimiliano; Fiorio, Mirta

    2016-01-01

    In the rubber hand illusion (RHI), watching a rubber hand being stroked in synchrony with one's own hidden hand may induce a sense of ownership over the rubber hand. The illusion relies on bottom-up multisensory integration of visual, tactile, and proprioceptive information, and on top-down processes through which the rubber hand is incorporated into pre-existing representations of the body. Although the degree of illusory experience varies largely across individuals, the factors influencing individual differences are unknown. We investigated whether sensory suggestibility might modulate susceptibility to the RHI. Sensory suggestibility is a personality trait related to how individuals react to sensory information. Because of its sensory nature, this trait could be relevant for studies using the RHI paradigm. Seventy healthy volunteers were classified by Sensory Suggestibility Scale (SSS) scores as having high or low suggestibility and assigned to either a high- (High-SSS) or a low-suggestibility (Low-SSS) group. Two components of the RHI were evaluated in synchronous and asynchronous stroking conditions: subjective experience of sense of ownership over the rubber hand via a 9-statement questionnaire, and proprioceptive drift as measured with a ruler. The High-SSS group was generally more susceptible to the subjective component; in the synchronous condition, they rated the statement assessing the sense of ownership higher than the Low-SSS group. The scores for this statement significantly correlated with the total SSS score, indicating that the higher the sensory suggestibility, the stronger the sense of ownership. No effect of sensory suggestibility on proprioceptive drift was observed, suggesting that the effect is specific for the subjective feeling of ownership. This study demonstrates that sensory suggestibility may contribute to participants' experience of the illusion and should be considered when using the RHI paradigm.

  12. Psychological wellness constructs: relationships and group differences

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    Liezl Gropp

    2007-03-01

    Full Text Available The objective of the study was to examine the relationships between several constructs that were hypothesised to be components underlying psychological wellness and to establish whether there were differences between managerial and non-managerial groups or between Black and White groups in respect of the wellness variables. The Personal Orientation Inventory (POI, Locus of Control Inventory (LOC, Sense of Coherence Scale (SOC, and the Bar-On EQ-I were administered to a random sample of 200 employees of a financial services company. Statistically significant differences were found between the groups on several of the wellness variables with the manager and White groups obtaining higher scores on these variables than their comparison groups. However, in respect of External Locus of Control, the non-manager and Black groups obtained the higher scores. Factor analytic results demonstrated that the wellness variables clustered in two correlated factors (r = 0,43 labeled psychological wellness and self-actualisation.

  13. Psychological wellness constructs: relationships and group differences

    OpenAIRE

    Liezl Gropp; Dirk Geldenhuys; Deléne Visser

    2007-01-01

    The objective of the study was to examine the relationships between several constructs that were hypothesised to be components underlying psychological wellness and to establish whether there were differences between managerial and non-managerial groups or between Black and White groups in respect of the wellness variables. The Personal Orientation Inventory (POI), Locus of Control Inventory (LOC), Sense of Coherence Scale (SOC), and the Bar-On EQ-I were administered to a random sample of 20...

  14. Psychological wellness constructs: Relationships and group differences.

    OpenAIRE

    2007-01-01

    The objective of the study was to examine the relationships between several constructs that were hypothesised to be components underlying psychological wellness and to establish whether there were differences between managerial and non-managerial groups or between Black and White groups in respect of the wellness variables. The Personal Orientation Inventory (POI), Locus of Control Inventory (LOC), Sense of Coherence Scale (SOC), and the Bar-On EQ-I were administered to a random sample of 200...

  15. Genome trees constructed using five different approaches suggest new major bacterial clades

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    Tatusov Roman L

    2001-10-01

    Full Text Available Abstract Background The availability of multiple complete genome sequences from diverse taxa prompts the development of new phylogenetic approaches, which attempt to incorporate information derived from comparative analysis of complete gene sets or large subsets thereof. Such attempts are particularly relevant because of the major role of horizontal gene transfer and lineage-specific gene loss, at least in the evolution of prokaryotes. Results Five largely independent approaches were employed to construct trees for completely sequenced bacterial and archaeal genomes: i presence-absence of genomes in clusters of orthologous genes; ii conservation of local gene order (gene pairs among prokaryotic genomes; iii parameters of identity distribution for probable orthologs; iv analysis of concatenated alignments of ribosomal proteins; v comparison of trees constructed for multiple protein families. All constructed trees support the separation of the two primary prokaryotic domains, bacteria and archaea, as well as some terminal bifurcations within the bacterial and archaeal domains. Beyond these obvious groupings, the trees made with different methods appeared to differ substantially in terms of the relative contributions of phylogenetic relationships and similarities in gene repertoires caused by similar life styles and horizontal gene transfer to the tree topology. The trees based on presence-absence of genomes in orthologous clusters and the trees based on conserved gene pairs appear to be strongly affected by gene loss and horizontal gene transfer. The trees based on identity distributions for orthologs and particularly the tree made of concatenated ribosomal protein sequences seemed to carry a stronger phylogenetic signal. The latter tree supported three potential high-level bacterial clades,: i Chlamydia-Spirochetes, ii Thermotogales-Aquificales (bacterial hyperthermophiles, and ii Actinomycetes-Deinococcales-Cyanobacteria. The latter group also

  16. Different modes of variation for each BG lineage suggest different functions

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    Chattaway, John; Ramirez-Valdez, R. Andrei; Chappell, Paul E.; Caesar, Joseph J. E.; Lea, Susan M.

    2016-01-01

    Mammalian butyrophilins have various important functions, one for lipid binding but others as ligands for co-inhibition of αβ T cells or for stimulation of γδ T cells in the immune system. The chicken BG homologues are dimers, with extracellular immunoglobulin variable (V) domains joined by cysteines in the loop equivalent to complementarity-determining region 1 (CDR1). BG genes are found in three genomic locations: BG0 on chromosome 2, BG1 in the classical MHC (the BF-BL region) and many BG genes in the BG region just outside the MHC. Here, we show that BG0 is virtually monomorphic, suggesting housekeeping function(s) consonant with the ubiquitous tissue distribution. BG1 has allelic polymorphism but minimal sequence diversity, with the few polymorphic residues at the interface of the two V domains, suggesting that BG1 is recognized by receptors in a conserved fashion. Any phenotypic variation should be due to the intracellular region, with differential exon usage between alleles. BG genes in the BG region can generate diversity by exchange of sequence cassettes located in loops equivalent to CDR1 and CDR2, consonant with recognition of many ligands or antigens for immune defence. Unlike the mammalian butyrophilins, there are at least three modes by which BG genes evolve. PMID:27628321

  17. Construction of Difference Equations Using Lie Groups

    Energy Technology Data Exchange (ETDEWEB)

    Axford, R.A.

    1998-08-01

    The theory of prolongations of the generators of groups of point transformations to the grid point values of dependent variables and grid spacings is developed and applied to the construction of group invariant numerical algorithms. The concepts of invariant difference operators and generalized discrete sources are introduced for the discretization of systems of inhomogeneous differential equations and shown to produce exact difference equations. Invariant numerical flux functions are constructed from the general solutions of first order partial differential equations that come out of the evaluation of the Lie derivatives of conservation forms of difference schemes. It is demonstrated that invariant numerical flux functions with invariant flux or slope limiters can be determined to yield high resolution difference schemes. The introduction of an invariant flux or slope limiter can be done so as not to break the symmetry properties of a numerical flux-function.

  18. The Suggestion of Some Comparative European Group Corporate Governance Standards after Financial Crisis, Corporate Scandals and Manipulation

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    Dinh Tran Ngoc Huy

    2016-01-01

    Full Text Available In past few years, corporate scandals and bankruptcy in US and Europe and other parts of the world show some certain evidence on weak corporate governance, weak internal control system and weak audit. Though there are a few researches which have been done in the field of international corporate governance standards, we believe that this field with more rooms to explore. Therefore, this paper chooses a different analytical approach and among its aims is to give some systematic opinions. First, it classifies European Group representative corporate governance (CG standards into two (2 groups: EASD and ECODA CG principles covered in group 1 and, group 2, including EFAMA Code and Corporate Practices from EBRD, so-called relative good CG group, while it uses ACCA and CFA principles as reference. Second, it , through analysis, shows differences between above set of standards which are and have been used as reference principles for many relevant organizations. Third, it establishes a selected comparative set of standards for European group representative corporate governance system in accordance to international standards. Last but not least, this paper covers some ideas and policy suggestions.

  19. Metacognition and Group Differences: A Comparative Study

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    Al-Hilawani, Yasser A.

    2014-01-01

    In this study, metacognition refers to performing visual analysis and discrimination of real life events and situations in naïve psychology, naïve physics, and naïve biology domains. It is used, along with measuring reaction time, to examine differences in the ability of four groups of students to select appropriate pictures that correspond with…

  20. Differences in problems of motivation in different special groups

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    Kunnen, E.S.; Steenbeek, H.W.

    1999-01-01

    In general, children with a range of special needs have below-average motivation and perceived control. We have investigated whether differences exist between the types of problem in different special groups. Theory distinguishes between two types: low motivation and perceived control can be based e

  1. Understanding Students' Attitudes about Group Work: What Does This Suggest for Instructors of Business?

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    Marks, Melanie Beth; O'Connor, Abigail H.

    2013-01-01

    A survey was administered to college students to gain insight into their attitudes about classroom group work. Students responded that group work is generally a positive experience; however, they do not necessarily prefer it to individual assignments. Students' responses also indicated concerns about instructors' motivations for using…

  2. Effects of Differences in Suggestibility within Self- and External-Control Conditions.

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    Souheaver, Gary T.; Schuldt, W. John

    1978-01-01

    Studied effects of suggestibility on performance within self- and external-control conditions. Subjects were assigned to experimental conditions--self-control, external-control, and no reward. Response rates of self and external groups were highest. Response rates of high-suggestibles in self-control conditions were not significantly different…

  3. Patterns of Ageism in Different Age Groups

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    Balázs John

    2013-08-01

    Full Text Available This paper examines age-based stereotypes in accordance with the Stereotype Content Model in four different age groups: schoolchildren, adolescents, adults and the elderly. Participants were asked to rank graphic portraits of both genders of four age clusters in terms of warmth and competence. The hypothesis that age groups, besides a positive evaluation of their own age cluster, would rate old people in an increasingly negative way as they themselves get older, was not confirmed. On the contrary, young children seem to have the most extreme prejudice against older people. Interestingly, adults and elderly appear to evaluate their own age cluster rather negatively too. Other relations between age groups indicate that ageism does not only affect old people and that it can include positive stereotypes as well. It is also argued, that ageism may have a changing pattern throughout the lifespan.

  4. Sarcopenia: Prevalence and associated factors based on different suggested definitions in community-dwelling older adults.

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    Kim, Hunkyung; Hirano, Hirohiko; Edahiro, Ayako; Ohara, Yuki; Watanabe, Yutaka; Kojima, Narumi; Kim, Miji; Hosoi, Erika; Yoshida, Yuko; Yoshida, Hideyo; Shinkai, Shoji

    2016-03-01

    The age-related loss of muscle mass and/or strength and performance, sarcopenia, has been associated with geriatric syndromes, morbidity and mortality. Although sarcopenia has been researched for many years, currently there is a lack of consensus on its definition. Some studies define sarcopenia as low muscle mass alone, whereas other studies have recently combined low muscle mass, strength and physical performance suggested by the European Working Group on Sarcopenia in Older People, as well as the Asian Working Group for Sarcopenia. The arbitrary use of various available sarcopenia definitions within the literature can cause discrepancies in the prevalence and associated risk factors. The application of population-specific cut-off values in any sample population can be problematic, particularly among different ethnicities. Using commonly used cut-off points to define sarcopenia, including solely muscle mass and combined definitions, on a community-dwelling elderly Japanese population, the prevalence of sarcopenia ranged from 2.5 to 28.0% in men and 2.3 to 11.7% in women, with muscle mass measured by dual-energy X-ray absorptiometry, and 7.1-98.0% in men and 19.8-88.0% in women measured by bioelectrical impedance analysis. Body mass index was the most prominent related factor for sarcopenia across the definitions in this Japanese sample. However, other associated hematological and chronic condition factors varied depending on the definition. © 2016 Japan Geriatrics Society.

  5. Sex Differences in Group Interaction and Task Performance.

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    Wood, Wendy; And Others

    Research on gender differences in group performance suggests that males excel at brainstorming while females excel at human relations and integration. To investigate the relations among gender, interaction style, and task performance, 264 college students (130 female, 134 male) worked in three person same sex groups on a production task which…

  6. Joint working group compliance on the Kyoto protocol: an overview of suggestions on compliance

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    Addink, G.H.

    1999-01-01

    Annex II of Decision 8/CP.4 from COP4 on "Preparation for the first session of the Conference of the Parties serving as the Meeting of the Parties to the Kyoto Protocol" established a joint working group (JWG) on compliance under the SBI and SBSTA.3 Because of the relation between the legal and the

  7. Age-group differences in inhibiting an oculomotor response.

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    Gottlob, Lawrence R; Fillmore, Mark T; Abroms, Ben D

    2007-11-01

    Age-group differences were examined in the delayed oculomotor response task, which requires that observers delay the execution of a saccade (eye movement) toward an abrupt-onset visual cue. This task differs from antisaccade and attentional capture in that inhibition causes saccades to be postponed, not redirected. Older adults executed more premature saccades than young adults, but there were no age-group differences in latency or accuracy of saccades executed at the proper time. The results suggest that older adults are less capable of inhibiting a prepotent saccadic response, but that other aspects of visual working memory related to the task are preserved.

  8. Grouping and crowding affect target appearance over different spatial scales.

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    Bilge Sayim

    Full Text Available Crowding is the impairment of peripheral target perception by nearby flankers. A number of recent studies have shown that crowding shares many features with grouping. Here, we investigate whether effects of crowding and grouping on target perception are related by asking whether they operate over the same spatial scale. A target letter T had two sets of flanking Ts of varying orientations. The first set was presented close to the target, yielding strong crowding. The second set was either close enough to cause crowding on their own or too far to cause crowding on their own. The Ts of the second set had the same orientation that either matched the target's orientation (Grouped condition or not (Ungrouped condition. In Experiment 1, the Grouped flankers reduced crowding independently of their distance from the target, suggesting that grouping operated over larger distances than crowding. In Experiments 2 and 3 we found that grouping did not affect sensitivity but produced a strong bias to report that the grouped orientation was present at the target location whether or not it was. Finally, we investigated whether this bias was a response or perceptual bias, rejecting the former in favor of a perceptual grouping explanation. We suggest that the effect of grouping is to assimilate the target to the identity of surrounding flankers when they are all the same, and that this shape assimilation effect differs in its spatial scale from the integration effect of crowding.

  9. Present-bias in different income groups

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    Can, B.; Erdem, O.

    2013-01-01

    The excessive use of credit cards and increasing consumer borrowing has been a major problem. Laibson (1997) suggests the present-bias problem as one of the driving forces of excessive borrowing. Shefrin and Thaler (1988) suggest that self-control underlies national borrowing/savings rate. We conduc

  10. Genome-wide analyses of recombination suggest that Giardia intestinalis assemblages represent different species.

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    Xu, Feifei; Jerlström-Hultqvist, Jon; Andersson, Jan O

    2012-10-01

    Giardia intestinalis is a major cause of waterborne enteric disease in humans. The species is divided into eight assemblages suggested to represent separate Giardia species based on host specificities and the genetic divergence of marker genes. We have investigated whether genome-wide recombination occurs between assemblages using the three available G. intestinalis genomes. First, the relative nonsynonymous substitution rates of the homologs were compared for 4,009 positional homologs. The vast majority of these comparisons indicate genetic isolation without interassemblage recombinations. Only a region of 6 kbp suggests genetic exchange between assemblages A and E, followed by gene conversion events. Second, recombination-detecting software fails to identify within-gene recombination between the different assemblages for most of the homologs. Our results indicate very low frequency of recombination between the syntenic core genes, suggesting that G. intestinalis assemblages are genetically isolated lineages and thus should be viewed as separated Giardia species.

  11. Simulations suggest that social and natural sciences differ in their research strategies adapted to work for different knowledge landscapes

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    Jaffe, Klaus

    2014-01-01

    Do different field of knowledge require different research strategies? A numerical model exploring different virtual knowledge landscapes, revealed different optimal search strategies. Trend following is maximized when the popularity of new discoveries determine the number of individuals researching it. This strategy works best when many researchers explore few large areas of knowledge. In contrast, individuals or small groups of researchers are better in discovering small bits of information in dispersed knowledge landscapes. The best technique for all situations simulated, is to adjust the number of researchers needed to explore a knowledge cluster according to the opportunities and the level of crowding in that cluster. Bibliometric data of scientific publications showed a continuous bipolar distribution of these strategies, ranging from natural sciences, with highly cited publications in journals containing a large number of articles, to the social sciences, with rarely cited publications in journals cont...

  12. Demographic Group Differences in Adolescents' Time Attitudes

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    Andretta, James R.; Worrell, Frank C.; Mello, Zena R.; Dixson, Dante D.; Baik, Sharon H.

    2013-01-01

    In the present study, we examined demographic differences in time attitudes in a sample of 293 adolescents. Time attitudes were measured using the Adolescent Time Attitude Scale (Mello & Worrell, 2007; Worrell, Mello, & Buhl, 2011), which assesses positive and negative attitudes toward the past, the present, and the future. Generally, African…

  13. Mitochondrial Genome Analyses Suggest Multiple Trichuris Species in Humans, Baboons, and Pigs from Different Geographical Regions.

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    Mohamed B F Hawash

    Full Text Available The whipworms Trichuris trichiura and Trichuris suis are two parasitic nematodes of humans and pigs, respectively. Although whipworms in human and non-human primates historically have been referred to as T. trichiura, recent reports suggest that several Trichuris spp. are found in primates.We sequenced and annotated complete mitochondrial genomes of Trichuris recovered from a human in Uganda, an olive baboon in the US, a hamadryas baboon in Denmark, and two pigs from Denmark and Uganda. Comparative analyses using other published mitochondrial genomes of Trichuris recovered from a human and a porcine host in China and from a françois' leaf-monkey (China were performed, including phylogenetic analyses and pairwise genetic and amino acid distances. Genetic and protein distances between human Trichuris in Uganda and China were high (~19% and 15%, respectively suggesting that they represented different species. Trichuris from the olive baboon in US was genetically related to human Trichuris in China, while the other from the hamadryas baboon in Denmark was nearly identical to human Trichuris from Uganda. Baboon-derived Trichuris was genetically distinct from Trichuris from françois' leaf monkey, suggesting multiple whipworm species circulating among non-human primates. The genetic and protein distances between pig Trichuris from Denmark and other regions were roughly 9% and 6%, respectively, while Chinese and Ugandan whipworms were more closely related.Our results indicate that Trichuris species infecting humans and pigs are phylogenetically distinct across geographical regions, which might have important implications for the implementation of suitable and effective control strategies in different regions. Moreover, we provide support for the hypothesis that Trichuris infecting primates represents a complex of cryptic species with some species being able to infect both humans and non-human primates.

  14. Epistemic Impact on Group Problem Solving for Different Science Majors

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    Mason, Andrew J

    2016-01-01

    Implementation of cognitive apprenticeship in an introductory physics lab group problem solving exercise may be mitigated by epistemic views toward physics of non-physics science majors. Quantitative pre-post data of the Force Concept Inventory (FCI) and Colorado Learning Attitudes About Science Survey (CLASS) of 39 students of a first-semester algebra-based introductory physics course, while describing typical results for a traditional-format course overall (g = +0.14), suggest differences in epistemic views between health science majors and life science majors which may correlate with differences in pre-post conceptual understanding. Audiovisual data of student lab groups working on a context-rich problem and students' written reflections described each group's typical dynamics and invoked epistemic games. We examined the effects of framework-based orientation (favored by biology majors) and performance-based orientation (favored by computer science, chemistry, and health science majors) on pre-post attitud...

  15. Differences in evolutionary pressure acting within highly conserved ortholog groups

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    Aravind L

    2008-07-01

    Full Text Available Abstract Background In highly conserved widely distributed ortholog groups, the main evolutionary force is assumed to be purifying selection that enforces sequence conservation, with most divergence occurring by accumulation of neutral substitutions. Using a set of ortholog groups from prokaryotes, with a single representative in each studied organism, we asked the question if this evolutionary pressure is acting similarly on different subgroups of orthologs defined as major lineages (e.g. Proteobacteria or Firmicutes. Results Using correlations in entropy measures as a proxy for evolutionary pressure, we observed two distinct behaviors within our ortholog collection. The first subset of ortholog groups, called here informational, consisted mostly of proteins associated with information processing (i.e. translation, transcription, DNA replication and the second, the non-informational ortholog groups, mostly comprised of proteins involved in metabolic pathways. The evolutionary pressure acting on non-informational proteins is more uniform relative to their informational counterparts. The non-informational proteins show higher level of correlation between entropy profiles and more uniformity across subgroups. Conclusion The low correlation of entropy profiles in the informational ortholog groups suggest that the evolutionary pressure acting on the informational ortholog groups is not uniform across different clades considered this study. This might suggest "fine-tuning" of informational proteins in each lineage leading to lineage-specific differences in selection. This, in turn, could make these proteins less exchangeable between lineages. In contrast, the uniformity of the selective pressure acting on the non-informational groups might allow the exchange of the genetic material via lateral gene transfer.

  16. Some Critical Differences between Self-Help and Therapy Groups.

    Science.gov (United States)

    Riordan, Richard J.; Beggs, Marilyn S.

    1988-01-01

    Presents a scheme for addressing differences between self-help groups and therapy groups, characterizing a list of group work parameters according to emphasis placed on each in therapy groups in contrast with self-help groups. Distinguishes between support groups, started by professional helping organizations or individuals, and self-help groups,…

  17. Complementation of the pha2 yeast mutant suggests functional differences for arogenate dehydratases from Arabidopsis thaliana.

    Science.gov (United States)

    Bross, Crystal D; Corea, Oliver R A; Kaldis, Angelo; Menassa, Rima; Bernards, Mark A; Kohalmi, Susanne E

    2011-08-01

    The final steps of phenylalanine (Phe) biosynthesis in bacteria, fungi and plants can occur via phenylpyruvate or arogenate intermediates. These routes are determined by the presence of prephenate dehydratase (PDT, EC4.2.1.51), which forms phenylpyruvate from prephenate, or arogenate dehydratase (ADT, EC4.2.1.91), which forms phenylalanine directly from arogenate. We compared sequences from select yeast species to those of Arabidopsis thaliana. The in silico analysis showed that plant ADTs and yeast PDTs share many common features allowing them to act as dehydratase/decarboxylases. However, plant and yeast sequences clearly group independently conferring distinct substrate specificities. Complementation of the Saccharomyces cerevisiae pha2 mutant, which lacks PDT activity and cannot grow in the absence of exogenous Phe, was used to test the PDT activity of A. thaliana ADTs in vivo. Previous biochemical characterization showed that all six AtADTs had high catalytic activity with arogenate as a substrate, while AtADT1, AtADT2 and AtADT6 also had limited activity with prephenate. Consistent with these results, the complementation test showed AtADT2 readily recovered the pha2 phenotype after ∼6 days growth at 30 °C, while AtADT1 required ∼13 days to show visible growth. By contrast, AtADT6 (lowest PDT activity) and AtADT3-5 (no PDT activity) were unable to recover the phenotype. These results suggest that only AtADT1 and AtADT2, but not the other four ADTs from Arabidopsis, have functional PDT activity in vivo, showing that there are two functional distinct groups. We hypothesize that plant ADTs have evolved to use the arogenate route for Phe synthesis while keeping some residual PDT activity.

  18. Distinction between Clock and Time, and a Suggested Experiment with Different Types of Clocks in GPS

    Science.gov (United States)

    Smarandache, Florentin

    2013-03-01

    The clock is an instrument for measuring the time, instrument that may not run perfectly (accurately) under certain conditions (like, say, in strong electromagnetic field, in strong gravitational field, in extremely high or low temperature, pressure, etc.), but this does not mean that time itself runs slower or faster as Einstein's Theory of Relativity asserts. We are referring to an absolute time, i.e. time measured not with respect to ether or non-ether, but with respect to an absolute mathematical reference frame. Several types of clocks could run at a more slowly rate in a moving frame of reference than other types of clocks; it depends on the construction material and functioning principle of each type of clock. Relativists say that ``gravity slows time''. This is incorrect, since actually gravity slows today's types of clocks. And one type of clock is slowed more or less than another type of clock. Not only gravity but other (electric, magnetic, etc.) fields or various medium composition elements or structures may slow or accelerate clocks that are in that medium. The clocks used today in the satellites for the GPS necessitate a correction with respect to the Earth clocks. But in the future, when new types of clocks will be built based on different construction material and functioning principle, the correction of the GPS clocks would be different. In order to make the distinction between ``clock'' and ``time'', we suggest a Experiment # 1 with different types of clocks for the GPS clocks, in order to prove that the resulted dilation and contraction factors are different from those obtained with today's cesium atomic clock.

  19. Functional gene analysis suggests different acetogen populations in the bovine rumen and tammar wallaby forestomach.

    Science.gov (United States)

    Gagen, Emma J; Denman, Stuart E; Padmanabha, Jagadish; Zadbuke, Someshwar; Al Jassim, Rafat; Morrison, Mark; McSweeney, Christopher S

    2010-12-01

    Reductive acetogenesis via the acetyl coenzyme A (acetyl-CoA) pathway is an alternative hydrogen sink to methanogenesis in the rumen. Functional gene-based analysis is the ideal approach for investigating organisms capable of this metabolism (acetogens). However, existing tools targeting the formyltetrahydrofolate synthetase gene (fhs) are compromised by lack of specificity due to the involvement of formyltetrahydrofolate synthetase (FTHFS) in other pathways. Acetyl-CoA synthase (ACS) is unique to the acetyl-CoA pathway and, in the present study, acetyl-CoA synthase genes (acsB) were recovered from a range of acetogens to facilitate the design of acsB-specific PCR primers. fhs and acsB libraries were used to examine acetogen diversity in the bovine rumen and forestomach of the tammar wallaby (Macropus eugenii), a native Australian marsupial demonstrating foregut fermentation analogous to rumen fermentation but resulting in lower methane emissions. Novel, deduced amino acid sequences of acsB and fhs affiliated with the Lachnospiraceae in both ecosystems and the Ruminococcaeae/Blautia group in the rumen. FTHFS sequences that probably originated from nonacetogens were identified by low "homoacetogen similarity" scores based on analysis of FTHFS residues, and comprised a large proportion of FTHFS sequences from the tammar wallaby forestomach. A diversity of FTHFS and ACS sequences in both ecosystems clustered between the Lachnospiraceae and Clostridiaceae acetogens but without close sequences from cultured isolates. These sequences probably originated from novel acetogens. The community structures of the acsB and fhs libraries from the rumen and the tammar wallaby forestomach were different (LIBSHUFF, P < 0.001), and these differences may have significance for overall hydrogenotrophy in both ecosystems.

  20. An individual differences approach to the suggestibility of memory over time.

    Science.gov (United States)

    Frost, Peter; Nussbaum, Gregory; Loconto, Taylor; Syke, Richard; Warren, Casey; Muise, Christina

    2013-04-01

    We examined how certain personality traits might relate to the formation of suggestive memory over time. We hypothesised that compliance and trust relate to initial acceptance of misinformation as memory, whereas fantasy proneness might relate to integration of misinformation into memory after later intervals (relative to the time of exposure to misinformation). Participants watched an excerpt from a movie--the simulated eyewitness event. They next answered a recall test that included embedded misinformation about the movie. Participants then answered a yes/no recognition test. A week later, participants answered a second yes/no recognition test about the movie (each yes/no recognition test included different questions). Before both recognition tests, participants were warned about the misinformation shown during recall and were asked to base their answer on the movie excerpt only. After completing the second recognition test, participants answered questions from the Neuroticism Extroversion Openness Personality Inventory-3 (McCrae, Costa, & Martin, 2005) and Creative Experiences Questionnaire (Merckelbach, Horselenberg, & Muris, 2001). While compliance correlated with misinformation effects immediately after exposure to misinformation, fantasy-prone personality accounted for more of the variability in false recognition rates than compliance after a 1-week interval.

  1. Suggestive evidence for association of two potassium channel genes with different idiopathic generalised epilepsy syndromes.

    Science.gov (United States)

    Chioza, B; Osei-Lah, A; Wilkie, H; Nashef, L; McCormick, D; Asherson, P; Makoff, A J

    2002-12-01

    Several potassium channel genes have been implicated in epilepsy. We have investigated three such genes, KCNJ3, KCNJ6 and KCNQ2, by association studies using a broad sample of idiopathic generalised epilepsy (IGE) unselected by syndrome. One of the two single nucleotide polymorphisms (SNPs) examined in one of the inward rectifying potassium channel genes, KCNJ3, was associated with IGE by genotype (P=0.0097), while its association by allele was of borderline significance (P=0.051). Analysis of the different clinical subgroups within the IGE sample showed more significant association with the presence of absence seizures (P=0.0041) and which is still significant after correction for multiple testing. Neither SNP in the other rectifying potassium channel gene, KCNJ6, was associated with IGE or any subgroup. None of the three SNPs in the voltage-gated potassium channel gene, KCNQ2, was associated with IGE. However, one SNP was associated with epilepsy with generalised tonic clonic seizures only (P=0.016), as was an SNP approximately 56 kb distant in the closely linked nicotinic acetylcholine gene CHRNA4 (P=0.014). These two SNPs were not in linkage disequilibrium with each other, suggesting that if they are not true associations they have independently occurred by chance. Neither association remains significant after correcting for multiple testing.

  2. Different inward and outward conduction mechanisms in NaVMs suggested by molecular dynamics simulations.

    Directory of Open Access Journals (Sweden)

    Song Ke

    2014-07-01

    Full Text Available Rapid and selective ion transport is essential for the generation and regulation of electrical signaling pathways in living organisms. Here, we use molecular dynamics (MD simulations with an applied membrane potential to investigate the ion flux of bacterial sodium channel NaVMs. 5.9 µs simulations with 500 mM NaCl suggest different mechanisms for inward and outward flux. The predicted inward conductance rate of ∼27±3 pS, agrees with experiment. The estimated outward conductance rate is 15±3 pS, which is considerably lower. Comparing inward and outward flux, the mean ion dwell time in the selectivity filter (SF is prolonged from 13.5±0.6 ns to 20.1±1.1 ns. Analysis of the Na+ distribution revealed distinct patterns for influx and efflux events. In 32.0±5.9% of the simulation time, the E53 side chains adopted a flipped conformation during outward conduction, whereas this conformational change was rarely observed (2.7±0.5% during influx. Further, simulations with dihedral restraints revealed that influx is less affected by the E53 conformational flexibility. In contrast, during outward conduction, our simulations indicate that the flipped E53 conformation provides direct coordination for Na+. The free energy profile (potential of mean force calculations indicates that this conformational change lowers the putative barriers between sites SCEN and SHFS during outward conduction. We hypothesize that during an action potential, the increased Na+ outward transition propensities at depolarizing potentials might increase the probability of E53 conformational changes in the SF. Subsequently, this might be a first step towards initiating slow inactivation.

  3. Diagnostic group differences in temporomandibular joint energy densities

    Science.gov (United States)

    Gallo, LM; Iwasaki, LR; Gonzalez, YM; Liu, H; Marx, DB; Nickel, JC

    2015-01-01

    Objectives Cartilage fatigue, due to mechanical work, may account for precocious development of degenerative joint disease in the temporomandibular joint (TMJ). This study compared energy densities (mJ/mm3) in TMJs of three diagnostic groups. Setting and Sample Population Sixty-eight subjects (44 women, 24 men) gave informed consent. Diagnostic criteria for temporomandibular disorders (DC/TMD) and imaging were used to group subjects according to presence of jaw muscle or joint pain (+P) and bilateral disc displacement (+DD). Material and Methods Subjects (+P+DD, n=16; −P+DD, n=16; and −P−DD, n=36) provided cone-beam computed tomography and magnetic resonance images, and jaw tracking data. Numerical modeling was used to determine TMJ loads (Fnormal). Dynamic stereometry was used to characterize individual-specific data of stress-field dynamics during 10 symmetrical jaw closing cycles. These data were used to estimate tractional forces (Ftraction). Energy densities were then calculated as W/Q(W=workdoneormechanicalenergyinput=tractionalforce×distanceofstress-fieldtranslation,Q=volumeofcartilage). ANOVA and Tukey-Kramer post-hoc analyses tested for intergroup differences. Results Mean ±standard error energy density for the +P+DD group was 12.7±1.5 mJ/mm3 and significantly greater (all adjusted p<0.04) when compared to −P+DD (7.4±1.4 mJ/mm3) and −P−DD (5.8±0.9 mJ/mm3) groups. Energy densities in −P+DD and −P−DD groups were not significantly different. Conclusion Diagnostic group differences in energy densities suggest that mechanical work may be a unique mechanism which contributes to cartilage fatigue in subjects with pain and disc displacement. PMID:25865545

  4. Ethnic Group Differences in the Outcomes of Multidisciplinary Pain Treatment

    Science.gov (United States)

    Merry, Brian; Campbell, Claudia M; Buenaver, Luis F.; McGuire, Lynanne; Haythornthwaite, Jennifer A.; Doleys, Daniel M.; Edwards, Robert R.

    2011-01-01

    Objectives The aim of this prospective investigation was to evaluate ethnic group differences in pain-related outcomes following multidisciplinary chronic pain treatment. A prospective pre- and post-treatment assessment design was employed to investigate the effects of ethnicity on changes in pain-related variables following completion of a multidisciplinary pain treatment program. Methods One hundred fifty five chronic pain patients participating in a multidisciplinary pain treatment program completed measures of pain and mood both prior to and following the four-week treatment. Primary outcome variables included pain severity, pain-related interference, and depressive symptoms. Results Baseline differences between African-Americans and Whites were observed for depressive symptoms, but not for pain severity or pain-related interference. Following multidisciplinary pain treatment, both White and African-American patients displayed post-treatment reductions in depressive symptoms and pain-related interference. However, White patients also reported reduced pain severity while African-Americans did not. Conclusions The treatment approach used in the present study appeared to be less effective in reducing self-reported pain severity in African-American versus White patients, though both groups benefited in terms of reduced depressive symptoms and pain-related interference. Moreover, the observation that improvements in functioning occurred without reductions in pain severity in African-American patients suggests that differences may exist in treatment processes as a function of ethnic group, and will consequently be an important area for future research. PMID:21731407

  5. Eliminating Age Differences in Children's and Adults' Suggestibility and Memory Conformity Effects

    Science.gov (United States)

    Otgaar, Henry; Howe, Mark L.; Brackmann, Nathalie; van Helvoort, Daniël H. J.

    2017-01-01

    We examined whether typical developmental trends in suggestion-induced false memories (i.e., age-related decrease) could be changed. Using theoretical principles from the spontaneous false memory field, we adapted 2 often-used false memory procedures: misinformation (Experiment 1) and memory conformity (Experiment 2). In Experiment 1, 7- to…

  6. Language-group Differences in Very Early Retirement in Finland

    Directory of Open Access Journals (Sweden)

    2002-07-01

    Full Text Available The purpose of this paper is to study very early retirement as an indicator for poor health, with focus on a comparison between the two language groups in Finland. Extensive longitudinal data are analysed with the help of random effects probit models. As expected from previous studies of mortality differences, the rate of retirement is lower among Swedish-speakers than among Finnish-speakers, and this cannot be attributed to socio-demographic and regional factors. Swedish-speaking males have a risk of very early retirement that is about 25 per cent lower than that of Finnish-speaking males. Among females the corresponding difference is about 15 per cent. Our results also suggest that not accounting for unobserved individual heterogeneity will bias the effect of native language downwards.

  7. Topological incongruence between nuclear and chloroplast DNA trees suggesting hybridization in the urophyllum group of the genus Fagopyrum (Polygonaceae).

    Science.gov (United States)

    Nishimoto, Yuriko; Ohnishi, Ohmi; Hasegawa, Masami

    2003-04-01

    We performed phylogenetic analyses of Fagopyrum species in the urophyllum group based on nucleotide sequences of two nuclear genes, FLORICAULA/LEAFY (FLO/LFY) and AGAMOUS (AG), and three segments of chloroplast DNA (cpDNA), rbcL-accD, trnK intron, and trnC-rpoB spacer. The FLO/LFY and AG sequences turned out to be phylogenetically more informative at the intrageneric level than the cpDNA sequences. Congruence among these gene trees, inferred by a maximum-likelihood (ML) method, demonstrated that topologies were partially incongruent between the nuclear and chloroplast DNA phylogenies. The nuclear DNA sequence data supported a monophyletic relation of F. statice, F. gilesii, and F. jinshaense, whereas the former two species formed another monophyletic relation with the F. capillatum-F. gracilipes-F. gracilipedoides-F. rubifolium clade excluding F. jinshaense in the synthetic cpDNA phylogeny. In addition, two divergent sequences of FLO/LFY were found in F. rubifolium (tetraploid). One of these was sister to F. gracilipedoides and another was sister to F. statice, and a monophyletic relation of these two genes was rejected by a bootstrap analysis. These results suggest that hybridization may have occurred during diversification of Fagopyrum species in the urophyllum group, and that F. rubifolium is possibly allotetraploid species.

  8. Epilepsy and Pregnancy: For healthy pregnancies and happy outcomes. Suggestions for service improvements from the Multispecialty UK Epilepsy Mortality Group.

    Science.gov (United States)

    Leach, J P; Smith, P E; Craig, J; Bagary, M; Cavanagh, D; Duncan, S; Kelso, A R C; Marson, A G; McCorry, D; Nashef, L; Nelson-Piercy, C; Northridge, R; Sieradzan, K; Thangaratinam, S; Walker, M; Winterbottom, J; Reuber, M

    2017-08-01

    Between 2009 and 2012 there were 26 epilepsy-related deaths in the UK of women who were pregnant or in the first post-partum year. The number of pregnancy-related deaths in women with epilepsy (WWE) has been increasing. Expert assessment suggests that most epilepsy-related deaths in pregnancy were preventable and attributable to poor seizure control. While prevention of seizures during pregnancy is important, a balance must be struck between seizure control and the teratogenic potential of antiepileptic drugs (AEDs). A range of professional guidance on the management of epilepsy in pregnancy has previously been issued, but little attention has been paid to how optimal care can be delivered to WWE by a range of healthcare professionals. We summarise the findings of a multidisciplinary meeting with representation from a wide group of professional bodies. This focussed on the implementation of optimal pregnancy epilepsy care aiming to reduce mortality of epilepsy in mothers and reduce morbidity in babies exposed to AEDs in utero. We identify in particular -What stage to intervene - Golden Moments of opportunities for improving outcomes -Which Key Groups have a role in making change -When - 2020 vision of what these improvements aim to achieve. -How to monitor the success in this field We believe that the service improvement ideas developed for the UK may provide a template for similar initiatives in other countries. Copyright © 2017 British Epilepsy Association. All rights reserved.

  9. Within-Group Differences in Sexual Orientation and Identity

    Science.gov (United States)

    Worthington, Roger L.; Reynolds, Amy L.

    2009-01-01

    The purpose of this investigation was to examine within-group differences among self-identified sexual orientation and identity groups. To understand these within-group differences, 2 types of analysis were conducted. First, a sample of 2,732 participants completed the Sexual Orientation and Identity Scale. Cluster analyses were used to identify 3…

  10. Within-Group Differences in Sexual Orientation and Identity

    Science.gov (United States)

    Worthington, Roger L.; Reynolds, Amy L.

    2009-01-01

    The purpose of this investigation was to examine within-group differences among self-identified sexual orientation and identity groups. To understand these within-group differences, 2 types of analysis were conducted. First, a sample of 2,732 participants completed the Sexual Orientation and Identity Scale. Cluster analyses were used to identify 3…

  11. Mitochondrial genome analyses suggest multiple Trichuris species in humans, baboons, and pigs from different geographical regions

    DEFF Research Database (Denmark)

    Hawash, Mohamed B. F.; Andersen, Lee O.; Gasser, Robin B.;

    2015-01-01

    BACKGROUND: The whipworms Trichuris trichiura and Trichuris suis are two parasitic nematodes of humans and pigs, respectively. Although whipworms in human and non-human primates historically have been referred to as T. trichiura, recent reports suggest that several Trichuris spp. are found...... in primates. METHODS AND FINDINGS: We sequenced and annotated complete mitochondrial genomes of Trichuris recovered from a human in Uganda, an olive baboon in the US, a hamadryas baboon in Denmark, and two pigs from Denmark and Uganda. Comparative analyses using other published mitochondrial genomes...... of Trichuris recovered from a human and a porcine host in China and from a françois' leaf-monkey (China) were performed, including phylogenetic analyses and pairwise genetic and amino acid distances. Genetic and protein distances between human Trichuris in Uganda and China were high (~19% and 15%, respectively...

  12. Quantifying and Interpreting Group Differences in Interest Profiles

    Science.gov (United States)

    Armstrong, Patrick Ian; Fouad, Nadya A.; Rounds, James; Hubert, Lawrence

    2010-01-01

    Research on group differences in interests has often focused on structural hypotheses and mean-score differences in Holland's (1997) theory, with comparatively little research on basic interest measures. Group differences in interest profiles were examined using statistical methods for matching individuals with occupations, the C-index, Q…

  13. Quantifying and Interpreting Group Differences in Interest Profiles

    Science.gov (United States)

    Armstrong, Patrick Ian; Fouad, Nadya A.; Rounds, James; Hubert, Lawrence

    2010-01-01

    Research on group differences in interests has often focused on structural hypotheses and mean-score differences in Holland's (1997) theory, with comparatively little research on basic interest measures. Group differences in interest profiles were examined using statistical methods for matching individuals with occupations, the C-index, Q…

  14. Meteoric Be-10 from Sirius Group suggests high elevation McMurdo Dry Valleys permanently frozen since 6 Ma

    Science.gov (United States)

    Dickinson, Warren W.; Schiller, Martin; Ditchburn, Bob G.; Graham, Ian J.; Zondervan, Albert

    2012-11-01

    A long-standing debate concerning Neogene Antarctic climate in the McMurdo Dry Valleys relies largely on evidence from landscape evolution, glacial modeling and stratigraphy. We provide new evidence from meteoric 10Be for the onset of frozen, hyper-arid conditions on a high elevation (1840 m) interfluve at Table Mountain. A simple decay model for the co-occurrence of meteoric 10Be and illuviated clay in cores of ice-cemented glacial sediments indicates that the clays were actively migrating down from the surface in a warm climate until the system froze between 6 and 9 Ma. Although this age range may be sensitive to possible interference by in situ produced 10Be, the implied minimum age of 6 Ma for the Sirius Group indicates that the Dry Valleys were permanently frozen down to this elevation at this time. The model also suggests denudation rates of 1-6 cm Myr-1 since freezing. These data provide an independent test of glacial-stratigraphic evidence used to determine Antarctic paleoclimate.

  15. Different groups, different motives: identity motives underlying changes in identification with novel groups.

    Science.gov (United States)

    Easterbrook, Matt; Vignoles, Vivian L

    2012-08-01

    Social identification is known to have wide-reaching implications, but theorists disagree about the underlying motives. Integrating motivated identity construction theory with recent social identity research, the authors predicted which motives underlie identification with two types of groups: interpersonal networks and social categories. In a five-wave longitudinal study of social identity processes among 268 new university residents, multilevel analyses showed that motives involved in identity enactment processes--self-esteem, belonging, and efficacy--significantly predicted within-person changes in identification with flatmates (an interpersonal network group), whereas motives involved in identity definition processes--meaning, self-esteem, and distinctiveness--significantly predicted within-person changes in identification with halls of residence (an abstract social category). This article discusses implications for research into identity motives and social identity.

  16. Sex Differences in Spatial Performance in the Elderly: A Review of the Literature and Suggestions for Research

    Science.gov (United States)

    Cohen, Donna

    1977-01-01

    This paper reviews the literature on sex differences in spatial performance in older persons, proposes a theory of measurement, operational psychogenetic structuralism, for the analysis of sex differences in cognition, and suggests research directions relevant to educational gerontology. (Author)

  17. Are interest groups different in the factors determining landscape preferences?

    Directory of Open Access Journals (Sweden)

    Maria Bacher

    2016-02-01

    Full Text Available In the last decades, rural landscape in Europe has evolved from an agricultural by-product to an important public good. This development creates not only new challenges to farming practices, it also makes participation and public involvement an indispensable tool for sustainable landscape planning. This is especially true for many European mountain regions, where tourism represents an important source of income and conflicts between locals’ and tourists’ interests should be avoided. In our study, we analyze whether discrepancies in the perception of the Alpine landscape can be located between locals and tourists and, if these differences exist, in which aspects these two groups are differing. A model employing three general factors able to describe landscape preferences regardless of the personal background is suggested and validated by confirmatory factor analysis. Our major finding shows that an attractive landscape for tourists does not have to be contradictory to a landscape that supports a high living quality for locals. Compromises in landscape planning between locals’ and tourists’ requirements seem often not to be necessary as they, generally, do not differ in the way they experience and assess the landscape.

  18. STUDIES ON HUMAN FALLOPIAN TUBAL EPITHELIUM IN DIFFERENT AGE GROUPS

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    Jayasri

    2016-02-01

    Full Text Available BACKGROUND AND AIMS The “fallopian tubes” (oviducts or uterine tubes are long paired flexuous reproductive organ which transports ova, spermatozoa, zygotes, the pre-implantation morulae and blastocyst. It has major role during reproductive period, but it remains as if vestigial organ before puberty and after menopause. Due to increasing rate of tubal block and infertility, oviducts and their structures gaining importance and have become a subject of research in present days particularly epithelium. The aim of the study is to ascertain any histological difference of tubal epithelium in different age groups and the research work could be utilized for investigation and management of infertility. MATERIALS AND METHODS Seven samples of each group i.e., prereproductive, reproductive & postmenopausal were collected from fresh unembalmed human cadavers received in the department of Anatomy, FAA Medical College, Barpeta, Assam. The slides were prepared using the standard laboratory procedure. Under low and high power objectives the type of cells were observed and epithelial height was measured in the different segments. Stress was given for any significant difference of epithelial height between the different age groups. RESULTS Study revealed that among the groups within the same segment, epithelial height was recorded highest (33.57µm in reproductive group as against the lowest (22.91µm in post-menopausal group. Epithelial structures of the prereproductive and reproductive groups were significantly differed (p<0.01 from the postmenopausal group. CONCLUSIONS From the findings of the present study it can be concluded that: 1. In all the groups fallopian tubal epithelium is of simple columnar type and contains three types of cells. Cells are ciliated, secretory & peg (intercalary cells. 2. In all the groups same type of increasing trend of epithelial height from intramural segment to ampullary segment was recorded. 3. In intergroup comparison of

  19. Different pH-sensitivity patterns of 30 sodium channel inhibitors suggest chemically different pools along the access pathway

    Science.gov (United States)

    Lazar, Alexandra; Lenkey, Nora; Pesti, Krisztina; Fodor, Laszlo; Mike, Arpad

    2015-01-01

    The major drug binding site of sodium channels is inaccessible from the extracellular side, drug molecules can only access it either from the membrane phase, or from the intracellular aqueous phase. For this reason, ligand-membrane interactions are as important determinants of inhibitor properties, as ligand-protein interactions. One-way to probe this is to modify the pH of the extracellular fluid, which alters the ratio of charged vs. uncharged forms of some compounds, thereby changing their interaction with the membrane. In this electrophysiology study we used three different pH values: 6.0, 7.3, and 8.6 to test the significance of the protonation-deprotonation equilibrium in drug access and affinity. We investigated drugs of several different indications: carbamazepine, lamotrigine, phenytoin, lidocaine, bupivacaine, mexiletine, flecainide, ranolazine, riluzole, memantine, ritanserin, tolperisone, silperisone, ambroxol, haloperidol, chlorpromazine, clozapine, fluoxetine, sertraline, paroxetine, amitriptyline, imipramine, desipramine, maprotiline, nisoxetine, mianserin, mirtazapine, venlafaxine, nefazodone, and trazodone. We recorded the pH-dependence of potency, reversibility, as well as onset/offset kinetics. As expected, we observed a strong correlation between the acidic dissociation constant (pKa) of drugs and the pH-dependence of their potency. Unexpectedly, however, the pH-dependence of reversibility or kinetics showed diverse patterns, not simple correlation. Our data are best explained by a model where drug molecules can be trapped in at least two chemically different environments: A hydrophilic trap (which may be the aqueous cavity within the inner vestibule), which favors polar and less lipophilic compounds, and a lipophilic trap (which may be the membrane phase itself, and/or lipophilic binding sites on the channel). Rescue from the hydrophilic and lipophilic traps can be promoted by alkalic and acidic extracellular pH, respectively. PMID:26441665

  20. Different pH-sensitivity patterns of 30 sodium channel inhibitors suggest chemically different pools along the access pathway.

    Directory of Open Access Journals (Sweden)

    Alexandra eLazar

    2015-09-01

    Full Text Available The major drug binding site of sodium channels is inaccessible from the extracellular side, drug molecules can only access it either from the membrane phase, or from the intracellular aqueous phase. For this reason, ligand-membrane interactions are as important determinants of inhibitor properties, as ligand-protein interactions. One way to probe this is to modify the pH of the extracellular fluid, which alters the ratio of charged vs. uncharged forms of some compounds, thereby changing their interaction with the membrane. In this electrophysiology study we used three different pH values: 6.0, 7.3 and 8.6 to test the significance of the protonation-deprotonation equilibrium in drug access and affinity. We investigated drugs of several different indications: carbamazepine, lamotrigine, phenytoin, lidocaine, bupivacaine, mexiletine, flecainide, ranolazine, riluzole, memantine, ritanserin, tolperisone, silperisone, ambroxol, haloperidol, chlorpromazine, clozapine, fluoxetine, sertraline, paroxetine, amitriptyline, imipramine, desipramine, maprotiline, nisoxetine, mianserin, mirtazapine, venlafaxine, nefazodone and trazodone. We recorded the pH-dependence of potency, reversibility, as well as onset/offset kinetics. As expected, we observed a strong correlation between the acidic dissociation constant (pKa of drugs and the pH-dependence of their potency. Unexpectedly, however, the pH-dependence of reversibility or kinetics showed diverse patterns, not simple correlation. Our data are best explained by a model where drug molecules can be trapped in at least two chemically different environments: A hydrophilic trap (which may be the aqueous cavity within the inner vestibule, which favors polar and less lipophilic compounds, and a lipophilic trap (which may be the membrane phase itself, and/or lipophilic binding sites on the channel. Rescue from the hydrophilic and lipophilic traps can be promoted by alkalic and acidic extracellular pH, respectively.

  1. ORGANIZATIONAL WORK GROUPS AND WORK TEAMS – APPROACHES AND DIFFERENCES

    Directory of Open Access Journals (Sweden)

    Raluca ZOLTAN

    2015-02-01

    Full Text Available Work groups and work teams represents basic structures of traditional and modern organizations, and during the time they have been intensively researched. However, managers often do not always consider the fundamental differences between groups and teams, which will lead to unrealistic goals and results below expectations. Thus, in the present paper we propose a review of the main researching approaches on groups and teams (psychosocial, socio-technical, and behavioral approach, in the third part of the paper being detailed the fundamental differences between groups and teams in the light of these approaches.

  2. Big Five personality group differences across academic majors

    DEFF Research Database (Denmark)

    Vedel, Anna

    characterisations are more than humoristic elements in TV shows; are there real, measurable personality differences among groups of academics? One way to study this is to look at students in different academic majors and examine whether they differ on the group level in broad personality traits. During the past...... decades, studies have regularly explored associations between enrolment in specific academic majors and scores on the Big Five personality traits; Neuroticism, Extraversion, Openness, Agreeableness, and Conscientiousness. The present review examines this research systematically, summarises group...... group differences in the Big Five personality traits were generally found in the included studies. None of the included studies reported effect sizes, though, so the magnitude of the obtained differences was not estimated. Consequently, effect sizes were calculated using means and standard deviations...

  3. Simulation Suggests that medical group mergers won't undermine the potential utility of health information exchanges.

    NARCIS (Netherlands)

    Rudin, R.S.; Schneider, E.C.; Volk, L.A.; Szolovits, P.; Salzberg, C.A.; Simon, S.R.; Bates, D.W.

    2012-01-01

    Federal and state agencies are investing substantial resources in the creation of community health information exchanges, which are consortia that enable independent health care organizations to exchange clinical data. However, under pressure to form accountable care organizations, medical groups ma

  4. Group differences in the heritability of items and test scores

    NARCIS (Netherlands)

    Wicherts, J.M.; Johnson, W.

    2009-01-01

    It is important to understand potential sources of group differences in the heritability of intelligence test scores. On the basis of a basic item response model we argue that heritabilities which are based on dichotomous item scores normally do not generalize from one sample to the next. If groups

  5. Modelling of human low frequency sound localization acuity demonstrates dominance of spatial variation of interaural time difference and suggests uniform just-noticeable differences in interaural time difference.

    Directory of Open Access Journals (Sweden)

    Rosanna C G Smith

    Full Text Available Sound source localization is critical to animal survival and for identification of auditory objects. We investigated the acuity with which humans localize low frequency, pure tone sounds using timing differences between the ears. These small differences in time, known as interaural time differences or ITDs, are identified in a manner that allows localization acuity of around 1° at the midline. Acuity, a relative measure of localization ability, displays a non-linear variation as sound sources are positioned more laterally. All species studied localize sounds best at the midline and progressively worse as the sound is located out towards the side. To understand why sound localization displays this variation with azimuthal angle, we took a first-principles, systemic, analytical approach to model localization acuity. We calculated how ITDs vary with sound frequency, head size and sound source location for humans. This allowed us to model ITD variation for previously published experimental acuity data and determine the distribution of just-noticeable differences in ITD. Our results suggest that the best-fit model is one whereby just-noticeable differences in ITDs are identified with uniform or close to uniform sensitivity across the physiological range. We discuss how our results have several implications for neural ITD processing in different species as well as development of the auditory system.

  6. Molecular Diversity of Anthracnose Pathogen Populations Associated with UK Strawberry Production Suggests Multiple Introductions of Three Different Colletotrichum Species.

    Science.gov (United States)

    Baroncelli, Riccardo; Zapparata, Antonio; Sarrocco, Sabrina; Sukno, Serenella A; Lane, Charles R; Thon, Michael R; Vannacci, Giovanni; Holub, Eric; Sreenivasaprasad, Surapareddy

    2015-01-01

    Fragaria × ananassa (common name: strawberry) is a globally cultivated hybrid species belonging to Rosaceae family. Colletotrichum acutatum sensu lato (s.l.) is considered to be the second most economically important pathogen worldwide affecting strawberries. A collection of 148 Colletotrichum spp. isolates including 67 C. acutatum s.l. isolates associated with the phytosanitary history of UK strawberry production were used to characterize multi-locus genetic variation of this pathogen in the UK, relative to additional reference isolates that represent a worldwide sampling of the diversity of the fungus. The evidence indicates that three different species C. nymphaeae, C. godetiae and C. fioriniae are associated with strawberry production in the UK, which correspond to previously designated genetic groups A2, A4 and A3, respectively. Among these species, 12 distinct haplotypes were identified suggesting multiple introductions into the country. A subset of isolates was also used to compare aggressiveness in causing disease on strawberry plants and fruits. Isolates belonging to C. nymphaeae, C. godetiae and C. fioriniae representative of the UK anthracnose pathogen populations showed variation in their aggressiveness. Among the three species, C. nymphaeae and C. fioriniae appeared to be more aggressive compared to C. godetiae. This study highlights the genetic and pathogenic heterogeneity of the C. acutatum s.l. populations introduced into the UK linked to strawberry production.

  7. Molecular Diversity of Anthracnose Pathogen Populations Associated with UK Strawberry Production Suggests Multiple Introductions of Three Different Colletotrichum Species.

    Directory of Open Access Journals (Sweden)

    Riccardo Baroncelli

    Full Text Available Fragaria × ananassa (common name: strawberry is a globally cultivated hybrid species belonging to Rosaceae family. Colletotrichum acutatum sensu lato (s.l. is considered to be the second most economically important pathogen worldwide affecting strawberries. A collection of 148 Colletotrichum spp. isolates including 67 C. acutatum s.l. isolates associated with the phytosanitary history of UK strawberry production were used to characterize multi-locus genetic variation of this pathogen in the UK, relative to additional reference isolates that represent a worldwide sampling of the diversity of the fungus. The evidence indicates that three different species C. nymphaeae, C. godetiae and C. fioriniae are associated with strawberry production in the UK, which correspond to previously designated genetic groups A2, A4 and A3, respectively. Among these species, 12 distinct haplotypes were identified suggesting multiple introductions into the country. A subset of isolates was also used to compare aggressiveness in causing disease on strawberry plants and fruits. Isolates belonging to C. nymphaeae, C. godetiae and C. fioriniae representative of the UK anthracnose pathogen populations showed variation in their aggressiveness. Among the three species, C. nymphaeae and C. fioriniae appeared to be more aggressive compared to C. godetiae. This study highlights the genetic and pathogenic heterogeneity of the C. acutatum s.l. populations introduced into the UK linked to strawberry production.

  8. Molecular Diversity of Anthracnose Pathogen Populations Associated with UK Strawberry Production Suggests Multiple Introductions of Three Different Colletotrichum Species

    Science.gov (United States)

    Baroncelli, Riccardo; Zapparata, Antonio; Sarrocco, Sabrina; Sukno, Serenella A.; Lane, Charles R.; Thon, Michael R.; Vannacci, Giovanni; Holub, Eric; Sreenivasaprasad, Surapareddy

    2015-01-01

    Fragaria × ananassa (common name: strawberry) is a globally cultivated hybrid species belonging to Rosaceae family. Colletotrichum acutatum sensu lato (s.l.) is considered to be the second most economically important pathogen worldwide affecting strawberries. A collection of 148 Colletotrichum spp. isolates including 67 C. acutatum s.l. isolates associated with the phytosanitary history of UK strawberry production were used to characterize multi-locus genetic variation of this pathogen in the UK, relative to additional reference isolates that represent a worldwide sampling of the diversity of the fungus. The evidence indicates that three different species C. nymphaeae, C. godetiae and C. fioriniae are associated with strawberry production in the UK, which correspond to previously designated genetic groups A2, A4 and A3, respectively. Among these species, 12 distinct haplotypes were identified suggesting multiple introductions into the country. A subset of isolates was also used to compare aggressiveness in causing disease on strawberry plants and fruits. Isolates belonging to C. nymphaeae, C. godetiae and C. fioriniae representative of the UK anthracnose pathogen populations showed variation in their aggressiveness. Among the three species, C. nymphaeae and C. fioriniae appeared to be more aggressive compared to C. godetiae. This study highlights the genetic and pathogenic heterogeneity of the C. acutatum s.l. populations introduced into the UK linked to strawberry production. PMID:26086351

  9. Seven law concepts on nuclear non-proliferation suggested by the International Group of Legal Experts (ILG)

    Energy Technology Data Exchange (ETDEWEB)

    Steen, G. [Djursholm (Sweden); Wredberg, L. [ILG Consultant LTD, Vienna (Austria)

    2001-03-01

    The ILG has worked as an independent group under the Swedish Support Programme on Nuclear Non-Proliferation in Central and Eastern Europe and Central Asia. The ILG's mission is concluded with this report. When developing the seven Law Concepts on national nuclear legislation that are presented in this report, the ILG has applied certain basic principles, which are firmly established in modern Western legislation. A summary of these principles is made here. They are essential cornerstones in laws and regulations that apply both to the nuclear industry and to other high technology areas, characterised by advanced safety and security requirements. Of essential importance is that the Operator alone is responsible for the fulfilment of requirements stipulated in laws and authority directives. The technical complexity of the nuclear industry and the far-reaching requirements on safety and security necessitate a qualified and complete national system of legislation and regulations. As all legislation in general, the nuclear legislation should be clear, easy to understand and give little room for misunderstandings and loopholes. It should also present the legally established requirements on safety and security in a form that facilitates the application and implementation by both state authorities, facility operators and individuals. The investigations of the causes of the Three Mile Island and Chernobyl accidents brought into focus the impact on nuclear safety from human failure. As a consequence, increased emphasis has since then been put on the development of an overall high safety culture in the nuclear field. It is recognised that a good safety culture also promotes the non-proliferation systems and safeguards measures and helps to reduce the risk of illicit trafficking. In a high safety culture environment, each individual facility employee has to be motivated and encouraged to carry out the assigned duties and responsibilities in accordance with rules and

  10. A novel virus genome discovered in an extreme environment suggests recombination between unrelated groups of RNA and DNA viruses

    Directory of Open Access Journals (Sweden)

    Diemer Geoffrey S

    2012-06-01

    Full Text Available Abstract Background Viruses are known to be the most abundant organisms on earth, yet little is known about their collective origin and evolutionary history. With exceptionally high rates of genetic mutation and mosaicism, it is not currently possible to resolve deep evolutionary histories of the known major virus groups. Metagenomics offers a potential means of establishing a more comprehensive view of viral evolution as vast amounts of new sequence data becomes available for comparative analysis. Results Bioinformatic analysis of viral metagenomic sequences derived from a hot, acidic lake revealed a circular, putatively single-stranded DNA virus encoding a major capsid protein similar to those found only in single-stranded RNA viruses. The presence and circular configuration of the complete virus genome was confirmed by inverse PCR amplification from native DNA extracted from lake sediment. The virus genome appears to be the result of a RNA-DNA recombination event between two ostensibly unrelated virus groups. Environmental sequence databases were examined for homologous genes arranged in similar configurations and three similar putative virus genomes from marine environments were identified. This result indicates the existence of a widespread but previously undetected group of viruses. Conclusions This unique viral genome carries implications for theories of virus emergence and evolution, as no mechanism for interviral RNA-DNA recombination has yet been identified, and only scant evidence exists that genetic exchange occurs between such distinct virus lineages. Reviewers This article was reviewed by EK, MK (nominated by PF and AM. For the full reviews, please go to the Reviewers' comments section.

  11. Identifying Differences in Cultural Behavior in Online Groups

    Energy Technology Data Exchange (ETDEWEB)

    Gregory, Michelle L.; Engel, David W.; Bell, Eric B.; Mcgrath, Liam R.

    2012-07-23

    We have developed methods to identify online communities, or groups, using a combination of structural information variables and content information variables from weblog posts and their comments to build a characteristic footprint for groups. We have worked with both explicitly connected groups and 'abstract' groups, in which the connection between individuals is in interest (as determined by content based features) and behavior (metadata based features) as opposed to explicit links. We find that these variables do a good job at identifying groups, placing members within a group, and helping determine the appropriate granularity for group boundaries. The group footprint can then be used to identify differences between the online groups. In the work described here we are interested in determining how an individual's online behavior is influenced by their membership in more than one group. For example, individuals belong to a certain culture; they may belong as well to a demographic group, and other 'chosen' groups such as churches or clubs. There is a plethora of evidence surrounding the culturally sensitive adoption, use, and behavior on the Internet. In this work we begin to investigate how culturally defined internet behaviors may influence behaviors of subgroups. We do this through a series of experiments in which we analyze the interaction between culturally defined behaviors and the behaviors of the subgroups. Our goal is to (a) identify if our features can capture cultural distinctions in internet use, and (b) determine what kinds of interaction there are between levels and types of groups.

  12. The effect of preoperative suggestions on perioperative dreams and dream recalls after administration of different general anesthetic combinations: a randomized trial in maxillofacial surgery.

    Science.gov (United States)

    Gyulaházi, Judit; Varga, Katalin; Iglói, Endre; Redl, Pál; Kormos, János; Fülesdi, Béla

    2015-01-01

    Images evoked immediately before the induction of anesthesia with the help of suggestions may influence dreaming during anesthesia.The aim of the study was to assess the incidence of evoked dreams and dream recalls by employing suggestions before induction of anesthesia while administering different general anesthetic combinations. This is a single center, prospective randomized including 270 adult patients scheduled for maxillofacial surgical interventions. Patients were assigned to control, suggestion and dreamfilm groups according to the psychological method used. According to the anesthetic protocol there were also three subgroups: etomidate & sevoflurane, propofol & sevoflurane, propofol & propofol groups. Primary outcome measure was the incidence of postoperative dreams in the non-intervention group and in the three groups receiving different psychological interventions. Secondary endpoint was to test the effect of perioperative suggestions and dreamfilm-formation training on the occurrance of dreams and recallable dreams in different general anesthesiological techniques. Dream incidence rates measured in the control group did not differ significantly (etomidate & sevoflurane: 40%, propofol & sevoflurane: 26%, propofol & propofol: 39%). A significant increase could be observed in the incidence rate of dreams between the control and suggestion groups in the propofol & sevoflurane (26%-52%) group (p = 0.023). There was a significant difference in the incidence of dreams between the control and dreamfilm subgroup in the propofol & sevoflurane (26% vs. 57%), and in the propofol & propofol group (39% vs.70%) (p = 0.010, and p = 0.009, respectively). Similar to this, there was a significant difference in dream incidence between the dreamfilm and the suggestion subgroups (44% vs. 70%) in the propofol & propofol group (p = 0.019). Propofol as an induction agent contributed most to dream formation and recalls (χ2-test p value: 0.005). The content of images and dreams

  13. Big Five personality group differences across academic majors

    DEFF Research Database (Denmark)

    Vedel, Anna

    2016-01-01

    During the past decades, a number of studies have explored personality group differences in the Big Five personality traits among students in different academic majors. To date, though, this research has not been reviewed systematically. This was the aim of the present review. A systematic litera...... effect sizes were found regularly. The results from the present review indicate that substantial personality group differences across academic majors exist. Implications for research and practice are discussed.......During the past decades, a number of studies have explored personality group differences in the Big Five personality traits among students in different academic majors. To date, though, this research has not been reviewed systematically. This was the aim of the present review. A systematic...... literature search identified twelve eligible studies yielding an aggregated sample size of 13,389. Eleven studies reported significant group differences in one or multiple Big Five personality traits. Consistent findings across studies were that students of arts/humanities and psychology scored high...

  14. Health inequalities and social group differences: what should we measure?

    Science.gov (United States)

    Murray, C. J.; Gakidou, E. E.; Frenk, J.

    1999-01-01

    Both health inequalities and social group health differences are important aspects of measuring population health. Despite widespread recognition of their magnitude in many high- and low-income countries, there is considerable debate about the meaning and measurement of health inequalities, social group health differences and inequities. The lack of standard definitions, measurement strategies and indicators has and will continue to limit comparisons--between and within countries, and over time--of health inequalities, and perhaps more importantly comparative analyses of their determinants. Such comparative work, however, will be essential to find effective policies for governments to reduce health inequalities. This article addresses the question of whether we should be measuring health inequalities or social group health differences. To help clarify the strengths and weaknesses of these two approaches, we review some of the major arguments for and against each of them. PMID:10444876

  15. Cytogenetic and Molecular Data Suggest Deuterodon pedri Eigenmann, 1907 (Teleostei: Characidae) Is a Member of an Ancient Coastal Group.

    Science.gov (United States)

    Coutinho-Sanches, Natália; Dergam, Jorge Abdala

    2015-10-01

    The genus Deuterodon has been taxonomically recently redefined. Seven of its species have been included in this genus, whereas three others are regarded as Incertae Sedis in Characidae. One of latter is Deuterodon pedri, an endemic species from Santo Antônio River in Minas Gerais. Cytogenetic and molecular data on 21 specimens of D. pedri allowed to reevaluate the phylogenetic position of this taxon. The specimens showed karyotypic formula 12m+12sm+20st+6a, low heterochromatin content, nucleolar organizer regions present in two chromosome pairs, and 10 and 2 labeled regions by fluorescence in situ hybridization with 18S and 5S probes respectively, a karyotype similar to Deuterodon stigmaturus. The phylogenetic tree generated by a cytochrome oxidase subunit I fragment revealed that D. pedri and Deuterodon singularis are closely related and are the sister-group of Deuterodon parahybae, Deuterodon iguape, Astyanax giton, Astyanax intermedius, Astyanax ribeirae, Astyanax scabripinnis, and Probolodus heterostomus. The same arrangement was partially recovered with the nuclear gene RAG2. Our data indicate the genus Deuterodon is not monophyletic and that it is closely related to other species that occur in Brazil coastal basins.

  16. Salient features of otoacoustic emissions are common across tetrapod groups and suggest shared properties of generation mechanisms.

    Science.gov (United States)

    Bergevin, Christopher; Manley, Geoffrey A; Köppl, Christine

    2015-03-17

    Otoacoustic emissions (OAEs) are faint sounds generated by healthy inner ears that provide a window into the study of auditory mechanics. All vertebrate classes exhibit OAEs to varying degrees, yet the biophysical origins are still not well understood. Here, we analyzed both spontaneous (SOAE) and stimulus-frequency (SFOAE) otoacoustic emissions from a bird (barn owl, Tyto alba) and a lizard (green anole, Anolis carolinensis). These species possess highly disparate macromorphologies of the inner ear relative to each other and to mammals, thereby allowing for novel insights into the biomechanical mechanisms underlying OAE generation. All ears exhibited robust OAE activity, and our chief observation was that SFOAE phase accumulation between adjacent SOAE peak frequencies clustered about an integral number of cycles. Being highly similar to published results from human ears, we argue that these data indicate a common underlying generator mechanism of OAEs across all vertebrates, despite the absence of morphological features thought essential to mammalian cochlear mechanics. We suggest that otoacoustic emissions originate from phase coherence in a system of coupled oscillators, which is consistent with the notion of "coherent reflection" but does not explicitly require a mammalian-type traveling wave. Furthermore, comparison between SFOAE delays and auditory nerve fiber responses for the barn owl strengthens the notion that most OAE delay can be attributed to tuning.

  17. The effects of different gender groupings on middle school students' performance in science lab

    Science.gov (United States)

    Drab, Deborah D.

    Grouping students for labs in science classes is a common practice. This mixed methods quasi-experimental action research study examines homogeneous and heterogeneous gender grouping strategies to determine what gender grouping strategy is the most effective in a coeducational science classroom setting. Sixth grade students were grouped in same-gender and mixed-gender groups, alternating each quarter. Over the course of an academic year, data were collected from four sources. The teacher-researcher observed groups working during hands-on activities to collect data on student behaviors. Students completed post-lab questionnaires and an end-of-course questionnaire about their preferences and experiences in the different grouping strategies. Student scores on written lab assignments were also utilized. Data analysis focused on four areas: active engagement, student achievement, student perceptions of success and cooperative teamwork. Findings suggest that teachers may consider grouping students of different ability levels according to different gender grouping strategies to optimize learning.

  18. Superstitions regarding health problems in different ethnic groups in Karachi.

    Science.gov (United States)

    Bukhari, S S I; Pardhan, A; Khan, A S; Ahmed, A; Choudry, F J; Pardhan, K; Nayeem, K; Khan, M

    2002-08-01

    To find out the superstitions regarding health problems in different ethnic groups, their implications over the socio-economic development of that group and to what extent can those superstitions be related to their level of literacy. The study was a questionnaire-based survey, 20 subjects from each ethnic group were selected by cluster sampling of residential areas where that particular group has its highest concentration, making a total of 100 subjects. It was found that most people (73%) do have some superstitious beliefs. Fifty percent of people believe in them as a part of culture and tradition, another 25% got them from their elders. No significant difference was found between different racial groups (p value = 0.9). According to literacy rate, 73.5% of literate community and 94.1% illiterate community were found to have superstitions. The occupation of the breadwinner of family didn't have a significant impact over the belief in superstitions (p value = 0.6). Majority of our population believes in superstitions, which are more common in illiterates. These superstitions not only predict health seeking behaviour of a person but also play a major role in shaping the response of a community to any health intervention program. Without the knowledge of these superstitions, effective community participation cannot be achieved.

  19. INDIVIDUAL PSYCHOLOGICAL CHARACTERISTICS OF RAILWAYS OPERATORS OF DIFFERENT AGE GROUPS

    Directory of Open Access Journals (Sweden)

    Bugaeva V. M.

    2015-10-01

    Full Text Available The article presents the results of the study of some individual psychological characteristics of the drivers of rail transport in the age groups 25–34 and 35–45 years. We have identified a number of differences between the two age groups associated with both features individually-psychological sphere, and in the psycho-physiological features. Features of age-related psychological differences can be explained by the age characteristics of the representatives of each group; psycho-physiological features of age differences may reflect developed in the course of a long professional activity features. We have also developed adaptive strategies, consciously or unconsciously selected during the long-running monotonous activities and in small social groups (teams of drivers allow, on the one hand, higher quality performance of their professional duties, on the other — to avoid the harmful effects of stressful situations at work. It can be assumed that the composition of drivers age group 35– 45 years is the result of natural selection, when those who did not cope with this type of activity is simply dismissed or transferred to other kinds of professions

  20. Impact of Education on the Income of Different Social Groups

    Science.gov (United States)

    Yue, Changjun; Liu, Yanping

    2007-01-01

    This study investigates, statistically and econometrically, the income level, income inequality, education inequality, and the relationship between education and income of different social groups, on the basis of the Chinese Urban Household Survey conducted in 2005, the Gini coefficient and the quartile regression method. Research findings…

  1. Testing for difference between two groups of functional neuroimaging experiments

    DEFF Research Database (Denmark)

    Nielsen, Finn Årup; Chen, Andrew C. N.; Hansen, Lars Kai

    2004-01-01

    We describe a meta-analytic method that tests for the difference between two groups of functional neuroimaging experiments. We use kernel density estimation in three-dimensional brain space to convert points representing focal brain activations into a voxel-based representation. We find the maximum...

  2. Seven law concepts on nuclear non-proliferation suggested by the International Group of Legal Experts (ILG)

    Energy Technology Data Exchange (ETDEWEB)

    Steen, G. [Djursholm (Sweden); Wredberg, L. [ILG Consultant LTD, Vienna (Austria)

    2001-03-01

    The ILG has worked as an independent group under the Swedish Support Programme on Nuclear Non-Proliferation in Central and Eastern Europe and Central Asia. The ILG's mission is concluded with this report. When developing the seven Law Concepts on national nuclear legislation that are presented in this report, the ILG has applied certain basic principles, which are firmly established in modern Western legislation. A summary of these principles is made here. They are essential cornerstones in laws and regulations that apply both to the nuclear industry and to other high technology areas, characterised by advanced safety and security requirements. Of essential importance is that the Operator alone is responsible for the fulfilment of requirements stipulated in laws and authority directives. The technical complexity of the nuclear industry and the far-reaching requirements on safety and security necessitate a qualified and complete national system of legislation and regulations. As all legislation in general, the nuclear legislation should be clear, easy to understand and give little room for misunderstandings and loopholes. It should also present the legally established requirements on safety and security in a form that facilitates the application and implementation by both state authorities, facility operators and individuals. The investigations of the causes of the Three Mile Island and Chernobyl accidents brought into focus the impact on nuclear safety from human failure. As a consequence, increased emphasis has since then been put on the development of an overall high safety culture in the nuclear field. It is recognised that a good safety culture also promotes the non-proliferation systems and safeguards measures and helps to reduce the risk of illicit trafficking. In a high safety culture environment, each individual facility employee has to be motivated and encouraged to carry out the assigned duties and responsibilities in accordance with rules and

  3. Neurogenesis in the water flea Daphnia magna (Crustacea, Branchiopoda) suggests different mechanisms of neuroblast formation in insects and crustaceans.

    Science.gov (United States)

    Ungerer, Petra; Eriksson, Bo Joakim; Stollewerk, Angelika

    2011-09-01

    Within euarthropods, the morphological and molecular mechanisms of early nervous system development have been analysed in insects and several representatives of chelicerates and myriapods, while data on crustaceans are fragmentary. Neural stem cells (neuroblasts) generate the nervous system in insects and in higher crustaceans (malacostracans); in the remaining euarthropod groups, the chelicerates (e.g. spiders) and myriapods (e.g. millipedes), neuroblasts are missing. In the latter taxa, groups of neural precursors segregate from the neuroectoderm and directly differentiate into neurons and glial cells. In all euarthropod groups, achaete-scute homologues are required for neuroblast/neural precursor group formation. In the insects Drosophila melanogaster and Tribolium castaneum achaete-scute homologues are initially expressed in clusters of cells (proneural clusters) in the neuroepithelium but expression becomes restricted to the future neuroblast. Subsequently genes such as snail and prospero are expressed in the neuroblasts which are required for asymmetric division and differentiation. In contrast to insects, malacostracan neuroblasts do not segregate into the embryo but remain in the outer neuroepithelium, similar to vertebrate neural stem cells. It has been suggested that neuroblasts are present in another crustacean group, the branchiopods, and that they also remain in the neuroepithelium. This raises the questions how the molecular mechanisms of neuroblast selection have been modified during crustacean and insect evolution and if the segregation or the maintenance of neuroblasts in the neuroepithelium represents the ancestral state. Here we take advantage of the recently published Daphnia pulex (branchiopod) genome and identify genes in Daphnia magna that are known to be required for the selection and asymmetric division of neuroblasts in the fruit fly D. melanogaster. We unambiguously identify neuroblasts in D. magna by molecular marker gene expression and

  4. Job Attitudes among Different Occupational Status Groups. An Economic Analysis.

    Science.gov (United States)

    Ronen, Simcha; Sadan, Simcha

    1984-01-01

    An economic model is applied to employee attitudinal variables to compare the contribution of intrinsic and extrinsic factors to job satisfaction for skilled workers and managers in an electronics manufacturing organization. Intrinsic rewards are found to increase in importance as employment level increases, suggesting different frames of…

  5. Properties of graphene inks stabilized by different functional groups

    Energy Technology Data Exchange (ETDEWEB)

    Wei Di; Li Hongwei; Bower, Chris; Andrew, Piers; Ryhaenen, Tapani [Nokia Research Centre, Broers Building, 21 JJ Thomson Avenue, Cambridge CB3 0FA (United Kingdom); Han Dongxue; Zhang Qixian; Niu Li; Yang Huafeng, E-mail: di.wei@nokia.com, E-mail: lniu@ciac.jl.cn [State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun City 130022, Jilin Province (China)

    2011-06-17

    Different graphene inks have been synthesized by chemical methods. These uniform dispersions were stabilized by various functional groups such as room temperature ionic liquid, polyaniline, polyelectrolyte (poly[2,5-bis(3-sulfonatopropoxy)-1,4-ethynylphenylene-alt-1, 4-ethynylphenylene] sodium salt) and poly(styrenesulfonate) (PSS). The dispersions can be easily cast into high-quality, free-standing films but with very different physiochemical properties such as surface tension and adhesion. SEM and AFM methods have been applied to have a detailed study of the properties of the inks. It is found that graphenes modified by p-type polyaniline show the highest surface tension. Diverse surface adhesive properties to the substrate are also found with various functional groups. The different viscoelasticities of graphene inks were related to the microscopic structure of their coating layer and subsequently related to the configuration, chemistry and molecular dimensions of the modifying molecules to establish the property-structure relationship. Modifications of graphene inks made from chemical reduction cannot only enable cost-effective processing for printable electronics but also extend the applications into, for example, self-assembly of graphene via bottom-up nano-architecture and surface energy engineering of the graphenes. To fabricate useful devices, understanding the surface properties of graphene inks is very important. It is the first paper of this kind to study the surface tension and adhesion of graphene influenced by different functional groups.

  6. Microscopic study of human spleen in different age groups

    Directory of Open Access Journals (Sweden)

    Lizamma Alex

    2015-07-01

    Full Text Available Background: The microscopic structure of spleen is variable depending on the developmental stage of the organ, and the age and immune status of the individual. The aim of the investigation was to study the microscopic structure of human spleen in different age groups, starting from a six month old foetus up to the eighth decade of life. Methods: Seventy formalin fixed human spleens obtained postmortem, were included in the study. They were classified into different age groups, in both sexes, for a detailed study of the microscopic details. Results: The white pulp of spleen showed peri-arteriolar lymphatic sheath (PALS and lymphatic follicles. The corona or mantle zone and the germinal centre were discernible in many of the Malpighian bodies. The marginal zone separating the red pulp from the white pulp also could be clearly demarcated. The marginal sinus and peri-follicular zone could be seen in some sections only. The capsule thickness, trabecular network, cellularity of white pulp and red pulp, the connective tissue framework seen in the red pulp etc., showed variations in the different age groups. Conclusion: The microscopic structure of spleen varies in different age groups, with the PALS and the white pulp showing scanty cellularity in the six month foetus, and almost uniform cellularity in all areas of spleen at full term. Thereafter the follicles showed increase in its cellularity up to the third decade, and then seemed becoming progressively atrophic. Further studies are required on age related changes in the cellular architecture of this organ correlating with its functions. [Int J Res Med Sci 2015; 3(7.000: 1701-1706

  7. Bone Mineral Density Evaluation in Four Different Occupational Groups

    Directory of Open Access Journals (Sweden)

    Mustafa Turgut Yıldızgören

    2015-04-01

    Full Text Available Objective: The aim of this study was to evaluate bone mineral density (BMD and to discuss the potential risk factors for osteoporosis in four different occupational groups. Materials and Methods: In this study, 100 males who were admitted to our clinics for their periodic occupational controls and 40 healthy subjects were included. Demographic features of the participants were recorded. BMD was evaluated by Dual-energy x-ray absorptiometry (DXA from lumbar vertebrae and proximal femur. Results: Participants were mainly from the following four occupational groups; accumulator manufacturers (n=30, 21.4%, painting workers (n=30, 21.4%, welders (n=15, 10.7%, and quartz miners (n=25, 17.9% sectors. In addition, there were 40 healthy subjects (28.6%. Compared with the control group, femoral neck T-scores (p=0.023 and Z-scores (p=0.031 were significantly lower in miners. L2-L4 BMD values were significantly lower in accumulator manufacturers (p=0.041 and quartz miners (p=0.022 as compared with the control group. Conclusion: Workers in the accumulator and mining sectors had lower BMD than control subjects. Clinicians should keep in mind occupational risk factors related with chemical exposure for osteoporosis while questioning osteoporosis risk factors. (Turkish Journal of Osteoporosis 2015;21: 19-22

  8. Different Polycomb group complexes regulate common target genes in Arabidopsis.

    Science.gov (United States)

    Makarevich, Grigory; Leroy, Olivier; Akinci, Umut; Schubert, Daniel; Clarenz, Oliver; Goodrich, Justin; Grossniklaus, Ueli; Köhler, Claudia

    2006-09-01

    Polycomb group (PcG) proteins convey epigenetic inheritance of repressed transcriptional states. Although the mechanism of the action of PcG is not completely understood, methylation of histone H3 lysine 27 (H3K27) is important in establishing PcG-mediated transcriptional repression. We show that the plant PcG target gene PHERES1 is regulated by histone trimethylation on H3K27 residues mediated by at least two different PcG complexes in plants, containing the SET domain proteins MEDEA or CURLY LEAF/SWINGER. Furthermore, we identify FUSCA3 as a potential PcG target gene and show that FUSCA3 is regulated by MEDEA and CURLY LEAF/SWINGER. We propose that different PcG complexes regulate a common set of target genes during the different stages of plant development.

  9. Latent cluster analysis of ALS phenotypes identifies prognostically differing groups.

    Directory of Open Access Journals (Sweden)

    Jeban Ganesalingam

    Full Text Available BACKGROUND: Amyotrophic lateral sclerosis (ALS is a degenerative disease predominantly affecting motor neurons and manifesting as several different phenotypes. Whether these phenotypes correspond to different underlying disease processes is unknown. We used latent cluster analysis to identify groupings of clinical variables in an objective and unbiased way to improve phenotyping for clinical and research purposes. METHODS: Latent class cluster analysis was applied to a large database consisting of 1467 records of people with ALS, using discrete variables which can be readily determined at the first clinic appointment. The model was tested for clinical relevance by survival analysis of the phenotypic groupings using the Kaplan-Meier method. RESULTS: The best model generated five distinct phenotypic classes that strongly predicted survival (p<0.0001. Eight variables were used for the latent class analysis, but a good estimate of the classification could be obtained using just two variables: site of first symptoms (bulbar or limb and time from symptom onset to diagnosis (p<0.00001. CONCLUSION: The five phenotypic classes identified using latent cluster analysis can predict prognosis. They could be used to stratify patients recruited into clinical trials and generating more homogeneous disease groups for genetic, proteomic and risk factor research.

  10. Gestational diabetes mellitus: Challenges for different ethnic groups.

    Science.gov (United States)

    Yuen, Lili; Wong, Vincent W

    2015-07-25

    Ethnicity is defined as "belonging to a social group that has a common national or cultural tradition". Membership of certain ethnic groups has long been associated with increased risk of gestational diabetes mellitus (GDM). Studies that examined ethnic differences amongst women with GDM were often conducted in western countries where women from various ethnic backgrounds were represented. The prevalence of GDM appears to be particularly high among women from South Asia and South East Asia, compared to Caucasian, African-American and Hispanic communities. For some, but not all ethnic groups, the body mass index is a risk factor for the development of GDM. Even within a particular ethnic group, those who were born in their native countries have a different risk profile for GDM compared to those born in western countries. In terms of treatment, medical nutrition therapy (MNT) plays a key role in the management of GDM and the prescription of MNT should be culturally sensitive. Limited studies have shown that women who live in an English-speaking country but predominantly speak a language other than English, have lower rates of dietary understanding compared with their English speaking counterparts, and this may affect compliance to therapy. Insulin therapy also plays an important role and there appears to be variation as to the progression of women who progress to requiring insulin among different ethnicities. As for peri-natal outcomes, women from Pacific Islander countries have higher rates of macrosomia, while women from Chinese backgrounds had lower adverse pregnancy outcomes. From a maternal outcome point of view, pregnant women from Asia with GDM have a higher incidence of abnormal glucose tolerance test results post-partum and hence a higher risk of future development of type 2 diabetes mellitus. On the other hand, women from Hispanic or African-American backgrounds with GDM are more likely to develop hypertension post-partum. This review highlights the fact

  11. Stable isotopes suggest differences in diet between historic and reintroduced Przewalskís horses in the Gobi desert

    Science.gov (United States)

    Burnik Šturm, Martina; Spasskaya, Natalia N.; Sablin, Mikhail V.; Voigt, Christian C.; Kaczensky, Petra

    2016-04-01

    In historic times, two wild equid species, the Przewalski᾽s horse (PH; Equus ferus przewalskii) and the Asiatic wild ass (khulan, KH; Equus hemionus), roamed the Eurasian steppes. By the end of the 1960s, PHs had been driven to extinction in the wild and the range of KHs became severely restricted to the least productive habitats. However, PHs survived in captivity and reintroductions since the 1990s have brought the species back to parts of its native range in Mongolia and northern China where they again overlap with KHs. Ecological research on PHs and KHs has increased in recent years, but very little information is available on the ecology of the original PHs prior to extinction in the wild. We applied stable isotope analysis (13C, 15N, and 2H) of segmentally cut tail hair of PHs and KHs, collected during expeditions in NW China and SW Mongolia in 1889-1899, to draw inferences about the species feeding ecology. We compared tail hair isotope patterns of historic individuals to those of their extant counterparts from the Mongolian Gobi. A previous study of isotopic tail hair signatures of extant PHs (N=6) and KHs (N=6) suggested species specific differences in diet, with PHs being year-round grazers, but KHs switching between being grazers in summer and mixed feeders in winter (Burnik Šturm et al., in prep.). The comparison of isotope patterns of extant with historic samples confirms diet seasonality in historic KHs (N=3), but detects the same seasonality in five out of six PHs, suggesting that historic PHs had a different isotopic dietary niche than extant PHs. While we are still unable to fully understand the underlying reasons for this change in PHs, our results clearly suggest that the isotopic dietary niche of PHs was wider in the past, suggesting a higher diet flexibility, and overlapped with that of KHs, suggesting a high competition potential over Gobi pastures between the two equid species in historic times. Reference: Burnik Šturm, M., Ganbaatar, O

  12. Prevalence of cilantro (Coriandrum sativum disliking among different ethnocultural groups

    Directory of Open Access Journals (Sweden)

    Mauer Lilli

    2012-05-01

    Full Text Available Abstract Background Cilantro, the leaf of the Coriandrum sativum plant, is an herb that is widely consumed globally and has purported health benefits ranging from antibacterial to anticancer activities. Some individuals report an extreme dislike for cilantro, and this may explain the different cilantro consumption habits between populations. However, the prevalence of cilantro dislike has not previously been reported in any population. The objective of this study was to determine the prevalence of cilantro dislike among different ethnocultural groups from a population of young adults living in Canada. Subjects (n = 1,639 between the ages of 20 and 29 years were participants of the Toronto Nutrigenomics and Health Study. Individuals rated their preference for cilantro on a 9-point scale from ‘dislike extremely’ to ‘like extremely’. Subjects also had the option to select ‘have not tried’ or ‘would not try’. Subjects who selected 1 to 4 were classified as disliking cilantro. Results The prevalence of dislike ranged from 3 to 21%. The proportion of subjects classified as disliking cilantro was 21% for East Asians, 17% for Caucasians, 14% for those of African descent, 7% for South Asians, 4% for Hispanics, and 3% for Middle Eastern subjects. Conclusions These findings show that the prevalence of cilantro dislike differs widely between various ethnocultural groups.

  13. Comparison between different reactions of group IV hydride with H

    Institute of Scientific and Technical Information of China (English)

    ZHANG; Shaolong; ZHANG; Xuqiang; ZHANG; Qinggang; ZHANG; Yici

    2006-01-01

    The four-dimensional time-dependent quantum dynamics calculations for reactions of group IV hydride with H are carried out by employing the semirigid vibrating rotor target model and the time-dependent wave packet method. The reaction possibility, cross section and rate constants for reactions (H+SiH4 and H+GeH4) in different initial vibrational and rotational states are obtained. The common feature for such kind of reaction process is summarized. The theoretical result is consistent with available measurement, which indicates the credibility of this theory and the potential energy surface.

  14. Percutaneous nephrolithotomy in children in different age groups

    DEFF Research Database (Denmark)

    Guven, Selcuk; Frattini, Antonio; Onal, Bulent

    2013-01-01

    in the participating centres in the PCNL Global Study, as categorised in different age groups. PATIENTS AND METHODS: •  The Clinical Research Office of the Endourological Society (CROES) Study was conducted from November 2007 to December 2009, and included 96 centres and >5800 patients. •  All children aged ≤14 years...... was preferred in 22 patients (20.5%). The overall mean operative duration was 97.02 min; blood transfusion rate, fever and stone-free rates were 9%, 14% and 70.1%, respectively. •  A comparison of the paediatric PCNL cases according to age groups showed no statistically significant differences between...... the subgroups for patient characteristics, co-morbidities, renal anomalies, or previous surgical history. •  In the evaluation of the operative details, the mean sheath size and nephrostomy tube size were larger in school-age children than the preschool children (P= 0.01 and 0.002, respectively...

  15. Patterns of bacteria-host associations suggest different ecological strategies between two reef building cold-water coral species

    Science.gov (United States)

    Meistertzheim, Anne.-Leila; Lartaud, Franck; Arnaud-Haond, Sophie; Kalenitchenko, Dimitri; Bessalam, Manon; Le Bris, Nadine; Galand, Pierre E.

    2016-08-01

    Cold-water corals (CWC) are main ecosystem engineers of the deep sea, and their reefs constitute hot-spots of biodiversity. However, their ecology remains poorly understood, particularly, the nature of the holobiont formed by corals with their associated bacterial communities. Here, we analyzed Madrepora oculata and Lophelia pertusa samples, collected from one location in a Mediterranean canyon in two different seasons (autumn and spring), in order to test for species specificity and temporal stability of the host-bacteria associations. The 16S rRNA sequencing revealed host-specific patterns of bacterial communities associated with L. pertusa and M. oculata, both in terms of community composition and diversity. All analyzed M. oculata polyps exhibited temporally and spatially similar bacterial communities dominated by haplotypes homologous to the known cnidarians-associated genus Endozoicomonas. In contrast, the bacterial communities associated with L. pertusa varied among polyps from the same colony, as well as among distinct colonies and between seasons. While the resilient consortium formed by M. oculata and its bacterial community fit the definition of holobiont, the versatility of the L. pertusa microbiome suggests that this association is more influenced by the environmental conditions or nutritional status. Our results thus highlight distinct host/microbes association strategies for these two closely related Scleractinians sharing the same habitat, suggesting distinct sensitivity to environmental change.

  16. Gender differences of athletes in different classification groups of sports and sport disciplines

    Directory of Open Access Journals (Sweden)

    Olena Tarasevych

    2016-04-01

    Full Text Available Purpose: to identify the percentage of masculine, androgynous and feminine figures in different classification groups, sports and sports disciplines, depending on the sport qualification. Material & Methods: the study was conducted on the basis of the Kharkiv State Academy of Physical Culture among students – representatives of different sports that have different athletic skills using analysis and compilation of scientific and methodical literature, survey, testing the procedure S. Bam "Masculinity / femininity "Processing and statistical data. Results: based on the testing method established S. Bam percentage masculine, androgynous and feminine personalities among athletes and athletes in various sports classification groups depending on their athletic skills. Conclusions: among sportsmen and women in a variety of classification groups of sports is not revealed feminine personalities; masculine identity, among both men and women predominate in sports; androgyny attitude towards men and women are different.

  17. Energetic differences between bacterioplankton trophic groups and coral reef resistance.

    Science.gov (United States)

    McDole Somera, Tracey; Bailey, Barbara; Barott, Katie; Grasis, Juris; Hatay, Mark; Hilton, Brett J; Hisakawa, Nao; Nosrat, Bahador; Nulton, James; Silveira, Cynthia B; Sullivan, Chris; Brainard, Russell E; Rohwer, Forest

    2016-04-27

    Coral reefs are among the most productive and diverse marine ecosystems on the Earth. They are also particularly sensitive to changing energetic requirements by different trophic levels. Microbialization specifically refers to the increase in the energetic metabolic demands of microbes relative to macrobes and is significantly correlated with increasing human influence on coral reefs. In this study, metabolic theory of ecology is used to quantify the relative contributions of two broad bacterioplankton groups, autotrophs and heterotrophs, to energy flux on 27 Pacific coral reef ecosystems experiencing human impact to varying degrees. The effective activation energy required for photosynthesis is lower than the average energy of activation for the biochemical reactions of the Krebs cycle, and changes in the proportional abundance of these two groups can greatly affect rates of energy and materials cycling. We show that reef-water communities with a higher proportional abundance of microbial autotrophs expend more metabolic energy per gram of microbial biomass. Increased energy and materials flux through fast energy channels (i.e. water-column associated microbial autotrophs) may dampen the detrimental effects of increased heterotrophic loads (e.g. coral disease) on coral reef systems experiencing anthropogenic disturbance.

  18. Understanding of Adultery in Families Belonging to Different Ethnic Groups

    Directory of Open Access Journals (Sweden)

    Akhmadeeva E. V.

    2014-01-01

    Full Text Available The results of a pilot study aimed at identifying and analyzing understanding of adultery in ethnically homogeneous families who are representatives of the Bashkir, Russian and Tatar of ethnic groups are presented. Within the framework of the psychological approach, family is regarded as the space of joint life activity, within which the specific needs of the people connected by ties of blood are satisfied. To achieve this goal, E. V. Akhmadeeva designed the inventory “My attitude to adultery”, in which respondents were asked to give the definition of adultery and to mention the reasons, based on which adultery may occur. Also, a modified version of the Rokeach Value Survey (RVS was used, allowing determining the spouses’ dominant values of a series of terminal and instrumental values. Marital satisfaction was detected with use of the marriage satisfaction questionnaire by V. V. Stolin, G. P. Butenko, T. L. Romanova. On the base of respondents’ answers in the questionnaire in order to define the level of satisfaction by marriage there have been distinguished three categories of people who consider their marriage to be successful, less successful and unsuccessful. Gender and age differences in understanding the adultery have been revealed. Having analyzed the works of outstanding psychologists there have been found out the psychological sense and meaning of “ethnic group”, “ethnic culture”, “sexual culture”, “adultery”. Identified dominant values of the spouses. The reasons of adultery commitment and non-commitment as respondents understand it have been found. As can be seen from this study, none ethnic group encourages adultery. However, the possibility of committing adultery is allowed, and there are differences in explaining the reasons for committing this action.

  19. Differences between Belgian and Brazilian group A Streptococcus epidemiologic landscape.

    Directory of Open Access Journals (Sweden)

    Pierre Robert Smeesters

    Full Text Available BACKGROUND: Group A Streptococcus (GAS clinical and molecular epidemiology varies with location and time. These differences are not or are poorly understood. METHODS AND FINDINGS: We prospectively studied the epidemiology of GAS infections among children in outpatient hospital clinics in Brussels (Belgium and Brasília (Brazil. Clinical questionnaires were filled out and microbiological sampling was performed. GAS isolates were emm-typed according to the Center for Disease Control protocol. emm pattern was predicted for each isolate. 334 GAS isolates were recovered from 706 children. Skin infections were frequent in Brasília (48% of the GAS infections, whereas pharyngitis were predominant (88% in Brussels. The mean age of children with GAS pharyngitis in Brussels was lower than in Brasília (65/92 months, p<0.001. emm-typing revealed striking differences between Brazilian and Belgian GAS isolates. While 20 distinct emm-types were identified among 200 Belgian isolates, 48 were found among 128 Brazilian isolates. Belgian isolates belong mainly to emm pattern A-C (55% and E (42.5% while emm pattern E (51.5% and D (36% were predominant in Brasília. In Brasília, emm pattern D isolates were recovered from 18.5% of the pharyngitis, although this emm pattern is supposed to have a skin tropism. By contrast, A-C pattern isolates were infrequently recovered in a region where rheumatic fever is still highly prevalent. CONCLUSIONS: Epidemiologic features of GAS from a pediatric population were very different in an industrialised country and a low incomes region, not only in term of clinical presentation, but also in terms of genetic diversity and distribution of emm patterns. These differences should be taken into account for designing treatment guidelines and vaccine strategies.

  20. MicroRNAs and phylogenomics resolve the relationships of Tardigrada and suggest that velvet worms are the sister group of Arthropoda.

    Science.gov (United States)

    Campbell, Lahcen I; Rota-Stabelli, Omar; Edgecombe, Gregory D; Marchioro, Trevor; Longhorn, Stuart J; Telford, Maximilian J; Philippe, Hervé; Rebecchi, Lorena; Peterson, Kevin J; Pisani, Davide

    2011-09-20

    Morphological data traditionally group Tardigrada (water bears), Onychophora (velvet worms), and Arthropoda (e.g., spiders, insects, and their allies) into a monophyletic group of invertebrates with walking appendages known as the Panarthropoda. However, molecular data generally do not support the inclusion of tardigrades within the Panarthropoda, but instead place them closer to Nematoda (roundworms). Here we present results from the analyses of two independent genomic datasets, expressed sequence tags (ESTs) and microRNAs (miRNAs), which congruently resolve the phylogenetic relationships of Tardigrada. Our EST analyses, based on 49,023 amino acid sites from 255 proteins, significantly support a monophyletic Panarthropoda including Tardigrada and suggest a sister group relationship between Arthropoda and Onychophora. Using careful experimental manipulations--comparisons of model fit, signal dissection, and taxonomic pruning--we show that support for a Tardigrada + Nematoda group derives from the phylogenetic artifact of long-branch attraction. Our small RNA libraries fully support our EST results; no miRNAs were found to link Tardigrada and Nematoda, whereas all panarthropods were found to share one unique miRNA (miR-276). In addition, Onychophora and Arthropoda were found to share a second miRNA (miR-305). Our study confirms the monophyly of the legged ecdysozoans, shows that past support for a Tardigrada + Nematoda group was due to long-branch attraction, and suggests that the velvet worms are the sister group to the arthropods.

  1. Small Group Learning: Do Group Members' Implicit Theories of Ability Make a Difference?

    Science.gov (United States)

    Beckmann, Nadin; Wood, Robert E.; Minbashian, Amirali; Tabernero, Carmen

    2012-01-01

    We examined the impact of members' implicit theories of ability on group learning and the mediating role of several group process variables, such as goal-setting, effort attributions, and efficacy beliefs. Comparisons were between 15 groups with a strong incremental view on ability (high incremental theory groups), and 15 groups with a weak…

  2. Small Group Learning: Do Group Members' Implicit Theories of Ability Make a Difference?

    Science.gov (United States)

    Beckmann, Nadin; Wood, Robert E.; Minbashian, Amirali; Tabernero, Carmen

    2012-01-01

    We examined the impact of members' implicit theories of ability on group learning and the mediating role of several group process variables, such as goal-setting, effort attributions, and efficacy beliefs. Comparisons were between 15 groups with a strong incremental view on ability (high incremental theory groups), and 15 groups with a weak…

  3. Body image and eating disturbances across ethnic groups: more similarities than differences.

    Science.gov (United States)

    Shaw, Heather; Ramirez, Lisa; Trost, Ariel; Randall, Pat; Stice, Eric

    2004-03-01

    Sociocultural models of eating pathology posit that ethnic minority groups should show fewer eating disturbances than Whites. Thus, the authors tested whether there were ethnic differences in eating disorder symptoms and risk factors for eating pathology and whether the relations between risk factors and eating pathology differed across ethnic groups, with data from adolescent and adult females (N = 785). Only 1 of the 14 tests of main effect differences between ethnic groups was significant and none of the 49 tests of whether ethnicity moderated the relations of risk factors to eating pathology were significant. Findings provide little support for the hypothesized ethnic differences in eating disturbances and suggest that ethnic minority groups have reached parity with Whites in this domain.

  4. Gender Similarities and Differences in Preadolescent Peer Groups

    Science.gov (United States)

    Xie, Hongling; Shi, Bing

    2009-01-01

    The Social Cognitive Mapping procedure was used to identify peer social groups in 26 fifth-grade classrooms from six elementary schools in a northeastern urban school district. Four group structural features were examined: size, the number of subcliques, cohesion, and salience hierarchy. Ethnic diversity index was calculated for each group. An…

  5. Different expression patterns of duplicated PHANTASTICA-like genes in Lotus japonicus suggest their divergent functions during compound leaf development

    Institute of Scientific and Technical Information of China (English)

    Jiang Hong LUO; Jun YAN; Lin WENG; Jun YANG; Zhong ZHAO; Jiang Hua CHEN; Xiao He HU; Da LUO

    2005-01-01

    Recent studies on leaf development demonstrate that the mechanism on the adaxial-abaxial polarity pattern formation could be well conserved among the far-related species, in which PHANTASTICA (PAHN)-like genes play important roles. In this study, we explored the conservation and diversity on functions of PHAN-like genes during the compound leaf development in Lotusjaponicus, a papilionoid legume. Two PHAN-like genes in L. japonicus, LjPHANa and LjPHANb,were found to originate from a gene duplication event and displayed different expression patterns during compound leaf development. Two mutants, reduced leaflets1 (rel1) and reduced leaflets3 (rel3), which exhibited decreased adaxial identity of leaflets and reduced leaflet initiation, were identified and investigated. The expression patterns of both LjPHANs in rel mutants were altered and correlated with abnormalities of compound leaves. Our data suggest that LjPHANa and LjPHANb play important but divergent roles in regulating adaxial-abaxial polarity of compound leaves in L. japonicus.

  6. The fasted/fed mouse metabolic acetylome: N6-acetylation differences suggest acetylation coordinates organ-specific fuel switching.

    Science.gov (United States)

    Yang, Li; Vaitheesvaran, Bhavapriya; Hartil, Kirsten; Robinson, Alan J; Hoopmann, Michael R; Eng, Jimmy K; Kurland, Irwin J; Bruce, James E

    2011-09-02

    The elucidation of extra-nuclear lysine acetylation has been of growing interest, as the cosubstrate for acetylation, acetyl CoA, is at a key metabolic intersection. Our hypothesis was that mitochondrial and cytoplasmic protein acetylation may be part of a fasted/re-fed feedback control system for the regulation of the metabolic network in fuel switching, where acetyl CoA would be provided by fatty acid oxidation, or glycolysis, respectively. To test this, we characterized the mitochondrial and cytoplasmic acetylome in various organs that have a high metabolic rate relative to their mass, and/or switch fuels, under fasted and re-fed conditions (brain, kidney, liver, skeletal muscle, heart muscle, white and brown adipose tissues). Using immunoprecipitation, coupled with LC-MS/MS label free quantification, we show there is a dramatic variation in global quantitative profiles of acetylated proteins from different organs. In total, 733 acetylated peptides from 337 proteins were identified and quantified, out of which 31 acetylated peptides from the metabolic proteins that may play organ-specific roles were analyzed in detail. Results suggest that fasted/re-fed acetylation changes coordinated by organ-specific (de)acetylases in insulin-sensitive versus -insensitive organs may underlie fuel use and switching. Characterization of the tissue-specific acetylome should increase understanding of metabolic conditions wherein normal fuel switching is disrupted, such as in Type II diabetes.

  7. Entrepreneurial networking differences: An ethnic in-group and out-group analysis

    Directory of Open Access Journals (Sweden)

    Boris Urban

    2011-03-01

    Full Text Available Orientation: Researching entrepreneurship using a network perspective is important, as social networks are assets for small business owners struggling to survive in competitive markets.Research purpose: The research question of this study has focused on what we can learn about entrepreneurial networking, considering that there is an under-explored and unarticulated set of networking principles and practices which have not been previously analysed in terms of a multiethnic country context.Motivation for the study: Often the lack of network use is reported as a feature of entrepreneurs, who have less opportunity to utilise formal social capital features. Social networks provided by extended family, community-based or organisational relationships are often theorised to supplement the effects of education, experience and financial capital.Research design, approach and method: Based on hypothesised differences in networking ties, network assistance and support relationships, a survey was used to collect data on quantitative measures. Descriptive statistics were calculated and differential tests were conducted to test the hypotheses.Main findings: Results indicate that entrepreneurial networking is largely independent on group composition. Generally at least some aspects of networking are generic and as a consequence, a more integrated view of networking can be adopted.Practical/managerial implications: The practical value of the present study points to several areas of interest to entrepreneurs, policy makers and educators, through demonstrating the multifaceted nature of entrepreneurial networks for different groups and their explanatory potential in understanding networking.Contribution/value-add: Despite the importance of entrepreneurial networking, little empirical or theoretical research has examined the dynamics of networking in a developing country context such as South Africa, which has lower than expected total entrepreneurship activity.

  8. Different Agendas? The Views of Different Occupational Groups on Special Needs Education

    Science.gov (United States)

    Lindqvist, G.; Nilholm, C.; Almqvist, L.; Wetso, G. -M.

    2011-01-01

    The purpose of the present paper is to investigate how different occupational groups explain why children have problems in school, how they believe schools should help these children and the role they believe that special educational needs coordinators (SENCOs) should have in such work. A questionnaire was distributed to all teaching and support…

  9. Suggested guidelines for the provision and assessment of orthodontic education in Europe. A report from the Professional Development Group of the EURO-QUAL BIOMED II Project.

    Science.gov (United States)

    Eaton, K A; Adamidis, J P; McDonald, J P; Seeholzer, H; Sieminska-Piekarczyk, B

    2000-12-01

    The suggested guidelines for the provision and assessment of Orthodontic education in Europe, which are introduced, set out, and discussed in this paper, resulted from the work of the Professional Development Group (PDG) of the EURO-QUAL BIOMED II project. They were published in the final report of the project, after comments had been received from a range of national and European bodies and societies, including the British and the European Orthodontic Societies, Royal Colleges, and the General Dental Council.

  10. An improved numerical model suggests potential differences of wind-blown sand between on Earth and Mars

    Science.gov (United States)

    Bo, T. L.; Fu, L. T.; Liu, L.; Zheng, X. J.

    2017-06-01

    The studies on wind-blown sand are crucial for understanding the change of climate and landscape on Mars. However, the disadvantages of the saltation models may result in unreliable predictions. In this paper, the saltation model has been improved from two main aspects, the aerodynamic surface roughness and the lift-off parameters. The aerodynamic surface roughness is expressed as function of particle size, wind strength, air density, and air dynamic viscosity. The lift-off parameters are improved through including the dependence of restitution coefficient on incident parameters and the correlation between saltating speed and angle. The improved model proved to be capable of reproducing the observed data well in both stable stage and evolution process. The modeling of wind-blown sand is promoted by all improved aspects, and the dependence of restitution coefficient on incident parameters could not be ignored. The constant restitution coefficient and uncorrelated lift-off parameter distributions would lead to both the overestimation of the sand transport rate and apparent surface roughness and the delay of evolution process. The distribution of lift-off speed and the evolution of lift-off parameters on Mars are found to be different from those on Earth. This may thus suggest that it is inappropriate to predict the evolution of wind-blown sand by using the lift-off velocity obtained in steady state saltation. And it also may be problematic to predict the wind-blown sand on Mars through applying the lift-off velocity obtained upon terrestrial conditions directly.

  11. Differences in Sleep Duration among Four Different Population Groups of Older Adults in South Africa.

    Science.gov (United States)

    Peltzer, Karl

    2017-05-09

    The study aims to investigate sleep duration in four different population groups in a national probability sample of older South Africans who participated in the Study of Global Ageing and Adult Health (SAGE) Wave 1. A national population-based cross-sectional study with a sample of 3284 aged 50 years or older in South Africa was conducted in 2008. The questionnaire included socio-demographic characteristics, health variables, and self-reported sleep duration. Results indicate that White Africans compared to other population groups had the lowest mean sleep duration (7.88 h among men and 7.46 h among women). The prevalence of short sleep was the highest among both men and women among the White African (18.8% in men and 16.9% in women) and Indian or Asian African population groups (14.5% in men and 17.1% in women), and lowest among both men and women in the Black African (7.0% in men and 6.5% in women) and multi-ancestry population groups (15.6% in men and 12.7% in women). The prevalence of long sleep was among both men and women the highest in the Black African population group (56.2% in men and 58.5% in women), and the lowest in the White African population group (36.4% in men and 24.3% in women). In a Poisson regression model, adjusted for sociodemographics and chronic disease status, coming from the male and female White African population group was associated with short sleep. In addition, coming from the Indian or Asian African population group was associated with short sleep. No population group differences were found regarding long sleep prevalence. White Africans reported more short sleep duration than the other population groups, while there were no racial or ethnic differences in long sleep. White Africans are more likely to have sleep durations that are associated with negative health outcomes. An explanation of the high short sleep prevalence among White Africans may be related to their racial or ethnic minority status in South Africa.

  12. Differences in Sleep Duration among Four Different Population Groups of Older Adults in South Africa

    Directory of Open Access Journals (Sweden)

    Karl Peltzer

    2017-05-01

    Full Text Available The study aims to investigate sleep duration in four different population groups in a national probability sample of older South Africans who participated in the Study of Global Ageing and Adult Health (SAGE Wave 1. A national population-based cross-sectional study with a sample of 3284 aged 50 years or older in South Africa was conducted in 2008. The questionnaire included socio-demographic characteristics, health variables, and self-reported sleep duration. Results indicate that White Africans compared to other population groups had the lowest mean sleep duration (7.88 h among men and 7.46 h among women. The prevalence of short sleep was the highest among both men and women among the White African (18.8% in men and 16.9% in women and Indian or Asian African population groups (14.5% in men and 17.1% in women, and lowest among both men and women in the Black African (7.0% in men and 6.5% in women and multi-ancestry population groups (15.6% in men and 12.7% in women. The prevalence of long sleep was among both men and women the highest in the Black African population group (56.2% in men and 58.5% in women, and the lowest in the White African population group (36.4% in men and 24.3% in women. In a Poisson regression model, adjusted for sociodemographics and chronic disease status, coming from the male and female White African population group was associated with short sleep. In addition, coming from the Indian or Asian African population group was associated with short sleep. No population group differences were found regarding long sleep prevalence. White Africans reported more short sleep duration than the other population groups, while there were no racial or ethnic differences in long sleep. White Africans are more likely to have sleep durations that are associated with negative health outcomes. An explanation of the high short sleep prevalence among White Africans may be related to their racial or ethnic minority status in South Africa.

  13. Sex differences in the emergence of leadership during competitions within and between groups.

    Science.gov (United States)

    Van Vugt, Mark; Spisak, Brian R

    2008-09-01

    This experiment investigated potential gender biases in the emergence of leadership in groups. Teams played a public-goods game under conditions of intra- or intergroup competition. We predicted and found a strong preference for female leaders during intragroup competition and male leaders during intergroup competition. Furthermore, during intragroup competition, a female leader was more instrumental than a male leader in raising group investments, but this pattern was reversed during intergroup competition. These findings suggest that particular group threats elicit specific gender-biased leader prototypes. We speculate about the evolutionary and cultural origins of these sex differences in the emergence of leadership.

  14. Internalin profiling and multilocus sequence typing suggest four Listeria innocua subgroups with different evolutionary distances from Listeria monocytogenes

    Directory of Open Access Journals (Sweden)

    Wang Jun

    2010-03-01

    Full Text Available Abstract Background Ecological, biochemical and genetic resemblance as well as clear differences of virulence between L. monocytogenes and L. innocua make this bacterial clade attractive as a model to examine evolution of pathogenicity. This study was attempted to examine the population structure of L. innocua and the microevolution in the L. innocua-L. monocytogenes clade via profiling of 37 internalin genes and multilocus sequence typing based on the sequences of 9 unlinked genes gyrB, sigB, dapE, hisJ, ribC, purM, gap, tuf and betL. Results L. innocua was genetically monophyletic compared to L. monocytogenes, and comprised four subgroups. Subgroups A and B correlated with internalin types 1 and 3 (except the strain 0063 belonging to subgroup C and internalin types 2 and 4 respectively. The majority of L. innocua strains belonged to these two subgroups. Subgroup A harbored a whole set of L. monocytogenes-L. innocua common and L. innocua-specific internalin genes, and displayed higher recombination rates than those of subgroup B, including the relative frequency of occurrence of recombination versus mutation (ρ/θ and the relative effect of recombination versus point mutation (r/m. Subgroup A also exhibited a significantly smaller exterior/interior branch length ratio than expected under the coalescent model, suggesting a recent expansion of its population size. The phylogram based on the analysis with correction for recombination revealed that the time to the most recent common ancestor (TMRCA of L. innocua subgroups A and B were similar. Additionally, subgroup D, which correlated with internalin type 5, branched off from the other three subgroups. All L. innocua strains lacked seventeen virulence genes found in L. monocytogenes (except for the subgroup D strain L43 harboring inlJ and two subgroup B strains bearing bsh and were nonpathogenic to mice. Conclusions L. innocua represents a young species descending from L. monocytogenes and

  15. Negative impact of asthma on patients in different age groups

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    Marcela Batan Alith

    2015-02-01

    Full Text Available Objective: To evaluate the impact of asthma on patients in Brazil, by age group (12-17 years, 18-40 years, and ≥ 41 years. Methods: From a survey conducted in Latin America in 2011, we obtained data on 400 patients diagnosed with asthma and residing in one of four Brazilian state capitals (São Paulo, Rio de Janeiro, Curitiba, and Salvador. The data had been collected using a standardized questionnaire in face-to-face interviews. For the patients who were minors, the parents/guardians had completed the questionnaire. The questions addressed asthma control, number of hospitalizations, number of emergency room visits, and school/work absenteeism, as well as the impact of asthma on the quality of life, sleep, and leisure. We stratified the data by the selected age groups. Results: The proportions of patients who responded in the affirmative to the following questions were significantly higher in the 12- to 17-year age group than in the other two groups: "Have you had at least one episode of severe asthma that prevented you from playing/exercising in the last 12 months?" (p = 0.012; "Have you been absent from school/work in the last 12 months?" (p < 0.001; "Have you discontinued your asthma relief or control medication in the last 12 months?" (p = 0.008. In addition, 30.2% of the patients in the 12- to 17-year age group reported that normal physical exertion was very limiting (p = 0.010 vs. the other groups, whereas 14% of the patients in the ≥ 41-year age group described social activities as very limiting (p = 0.011 vs. the other groups. Conclusions: In this sample, asthma had a greater impact on the patients between 12 and 17 years of age, which might be attributable to poor treatment compliance.

  16. Negative impact of asthma on patients in different age groups.

    Science.gov (United States)

    Alith, Marcela Batan; Gazzotti, Mariana Rodrigues; Montealegre, Federico; Fish, James; Nascimento, Oliver Augusto; Jardim, José Roberto

    2015-01-01

    To evaluate the impact of asthma on patients in Brazil, by age group (12-17 years, 18-40 years, and ≥ 41 years). From a survey conducted in Latin America in 2011, we obtained data on 400 patients diagnosed with asthma and residing in one of four Brazilian state capitals (São Paulo, Rio de Janeiro, Curitiba, and Salvador). The data had been collected using a standardized questionnaire in face-to-face interviews. For the patients who were minors, the parents/guardians had completed the questionnaire. The questions addressed asthma control, number of hospitalizations, number of emergency room visits, and school/work absenteeism, as well as the impact of asthma on the quality of life, sleep, and leisure. We stratified the data by the selected age groups. The proportions of patients who responded in the affirmative to the following questions were significantly higher in the 12- to 17-year age group than in the other two groups: "Have you had at least one episode of severe asthma that prevented you from playing/exercising in the last 12 months?" (p = 0.012); "Have you been absent from school/work in the last 12 months?" (p your asthma relief or control medication in the last 12 months?" (p = 0.008). In addition, 30.2% of the patients in the 12- to 17-year age group reported that normal physical exertion was very limiting (p = 0.010 vs. the other groups), whereas 14% of the patients in the ≥ 41-year age group described social activities as very limiting (p = 0.011 vs. the other groups). In this sample, asthma had a greater impact on the patients between 12 and 17 years of age, which might be attributable to poor treatment compliance.

  17. Compound specific isotopic fractionation patterns suggest different carbon metabolisms among Chloroflexus-like bacteria in hot spring microbial mats

    NARCIS (Netherlands)

    Sinninghe Damsté, J.S.; Meer, M.T.J. van der; Schouten, S.; Leeuw, J.W. de; Ward, D.M.

    2003-01-01

    Stable carbon isotope fractionations between dissolved inorganic carbon and lipid biomarkers suggest photoautotrophy by Chloroflexus-like organisms in sulfidic and nonsulfidic Yellowstone hot springs. Where co-occurring, cyanobacteria appear to cross-feed Chloroflexus-like organisms supporting photo

  18. Features of Chronic Bronchitis in Different Age Groups

    Directory of Open Access Journals (Sweden)

    Galina L. Ignatova

    2014-03-01

    Full Text Available Background: Lung diseases are assuming greater relevance and importance today. Chronic bronchitis is a self-nosology, which may precede the development of COPD, the importance of which can hardly be overestimated. The main problem in this disease is caused by late diagnosis and treatment due to the delay by patients in seeking medical help. The aim of the work was to study the distribution and exposure to tobacco smoke, especially chronic bronchitis, depending on various factors, including age. Methods: We examined 1779 persons, including 855 men and 924 women. The mean age of the population was 35.83±8.3 years. We conducted surveys and spirometry. The outcome was assessed after a bronchodilation test was performed with salbutamol 400 mcg. We performed all statistical analysis using software package Statistica 10. Results: We identified chronic bronchitis in 9.2% of the cases in the group of younger individuals and in 14.9% of the cases in the group of older individuals, during the active detection of chronic bronchitis using questionnaires. The prevalence of cigarette smoking was slightly higher among the younger (39.5% than the older persons (33.6%; the frequency of smoking in a group of chronic bronchitis was reliably higher. Also, in this group, the performance spirometry reliably decreased. Conclusions: Outpatient survey is an effective method of identifying chronic bronchitis. Smoking is a major risk factor in the group of young respondents and the prevalence of smoking is inversely related to the education level of the respondents, regardless of age. As the decline in the Forced Expiratory Volume (FEV1 and FEV1/FVC is the main criterion diagnosis of COPD, it revealed significant declines in the FEV1 of the younger smoking individuals, which may help to predict the development of COPD in the older age group.

  19. [Lactase polymorphism in representatives of different ethnic-territorial groups].

    Science.gov (United States)

    Kozlov, A I; Sheremet'eva, V A; Kondik, V M

    1992-01-01

    Lactase polymorphism was studied in the native population of West Siberia and also in Buryatia. LAC*R frequency observed is-Khants- 0.8367, Mansi - 0.8660, Nenets - 0.8944, Buryats - 0.6883. The data obtained are considered to be the result of natural selection under traditional historical economical-cultural environment of the ethnic groups in question.

  20. Identification, modeling, and characterization studies of Tetrahymena thermophila myosin FERM domains suggests a conserved core fold but functional differences.

    Science.gov (United States)

    Martin, Che L; Singh, Shaneen M

    2015-11-01

    Myosins (MYO) define a superfamily of motor proteins which facilitate movement along cytoskeletal actin filaments in an ATP-dependent manner. To date, over 30 classes of myosin have been defined that vary in their roles and distribution across different taxa. The multidomain tail of myosin is responsible for the observed functional differences in different myosin classes facilitating differential binding to different cargos. One domain found in this region, the FERM domain, is found in several diverse proteins and is involved in many biological functions ranging from cell adhesion and actin-driven cytoskeleton assembly to cell signaling. Recently, new classes of unconventional myosin have been identified in Tetrahymena thermophila. In this study, we have identified, modeled, and characterized eight FERM domains from the unconventional T. thermophila myosins as their complete functional MyTH4-FERM cassettes. Our results reveal notable sequence, structural, and electrostatic differences between T. thermophila and other characterized FERM domains. Specifically, T. thermophila FERM domains contain helical inserts or extensions, which contribute to significant differences in surface electrostatic profiles of T. thermophila myosin FERMs when compared to the conventional FERM domains. Analyses of the modeled domains reveal differences in key functional residues as well as phosphoinositide-binding signatures and affinities. The work presented here broadens the scope of our understanding of myosin classes and their inherent functions, and provides a platform for experimentalists to design rational experimental studies to test the functional roles for T. thermophila myosins.

  1. THE DIFFERENCES OF DRIVING BEHAVIOR AMONG DIFFERENT DRIVER AGE GROUPS AT SIGNALIZED INTERSECTIONS

    Directory of Open Access Journals (Sweden)

    Jian John LU, Ph.D., P.E.

    2000-01-01

    Full Text Available Over the past few years the population of older drivers has substantially increased across the United States. Older drivers are a group of special interest because of their potential age-related deficiencies. It is essential to understand their driving behavior and adjust the conditions of roadway systems according to their requirements. Likewise, driving behavior of older drivers needs to be considered in order to adequately estimate capacities at intersections. In the past few years, research projects were performed by the University of South Florida to analyze the differences of driving behavior among different driver age groups. Typically, the driving behavior of older drivers was evaluated by analyzing their start-up lost time and saturation headway at signalized intersections as compared to young and mid-age driver groups. Research results were based on data collected from signalized intersections with different land-use types. These intersections are located in west and central Florida where the elderly population has been increasing rapidly in recent years. From the results it was found that the presence of older drivers significantly reduced intersection capacity at all study sites because of their higher lost times and lower saturation flow rates. Therefore, driving behavior of older drivers should be considered in designing intersections located in places with a significant older driver population. In the research, models were developed to predict start-up lost time and saturation headway values generated by older drivers. Then, the variation in capacities with an increasing percentage of older drivers in the traffic stream was modeled. Finally, adjustment factors for different percentages of older drivers were developed to adjust intersection capacity. These factors are believed to account for the presence of older drivers in the traffic stream. The adjustment factors may be used in capacity analysis and design procedures for

  2. Food risk perceptions by different consumer groups in Germany

    OpenAIRE

    Roosen, Jutta; Thiele, Silke; Hansen, Kristin

    2004-01-01

    This paper presents an analysis of the changing food risk perceptions of German consumers over the period 1992 to 2002. We analyse the respondents' general risk attitudes and their specific perceptions of food risks. Using cluster analysis we generate a typology of four consumer types. One group is worried about natural food risks, the second does not worry about any types of food risks, the third is concerned about technical food risks and the fourth is concerned about all food risks. A mult...

  3. Integrating Gender and Group Differences into Bridging Strategy

    Science.gov (United States)

    Yılmaz, Serkan; Eryılmaz, Ali

    2010-08-01

    The main goal of this study was to integrate gender and group effect into bridging strategy in order to assess the effect of bridging analogy-based instruction on sophomore students' misconceptions in Newton's Third Law. Specifically, the authors developed and benefited from anchoring analogy diagnostic test to merge the effect of group and gender into the strategy. Newton's third law misconception test, attitude scale toward Newton's third law, and classroom observation checklists were the other measuring tools utilized throughout this quasi-experimental study. The researchers also developed or used several teaching/learning materials such as gender and group splitted concept diagrams, lesson plans, gender splitted frequency tables, make sense scales, PowerPoint slides, flash cards, and demonstrations. The convenience sample of the study chosen from the accessible population involved 308 students from two public universities. The results of multivariate analysis of covariance indicated that the bridging strategy had a significant effect on students' misconceptions in Newton's third law whereas it had no significant effect on students' attitudes toward Newton's third law.

  4. Attachment disorganization in different clinical groups: What underpins unresolved attachment?

    Directory of Open Access Journals (Sweden)

    Juen Florian

    2013-01-01

    Full Text Available This paper summarizes findings and clinical implications of research on attachment disorganization in diverse clinical groups. Disorganized/unresolved attachment is overrepresented in these groups compared to healthy control participants, but disorder specific characteristics of this attachment pattern are still poorly understood. The focus of this study was to explore defensive processes in participants whose narratives were classified as disorganized/unresolved using the Adult Attachment Projective Picture System (AAP. Besides the predominance of disorganized attachment, clinical participants demonstrated more “segregated system material” especially in stories representing aloneness and more “Personal Experience material” compared to healthy individuals. Within the disorganized/ unresolved clinical individuals, BPD and PTSD patients showed the highest proportion of attachment disorganization and were less able to use other attachment-related defenses to maintain organized. Furthermore, PTSD patients were emotionally overwhelmed by the projective attachment scenes compared to the other clinical groups as indexed by an incapacity to complete sections of the AAP. BPD and addicted patients were characterized by a high degree of self-other boundary confusion. Depressive and schizophrenic patients showed a high overall defensive intensity to remain organized.

  5. Importance of life domains in different cultural groups.

    Science.gov (United States)

    Elizur, Dov; Kantor, Jeffrey; Yaniv, Eyal; Sagie, Abraham

    2008-01-01

    This study assessed the role of individualism and collectivism in the shaping of personal values of Canadians, Israelis, and Palestinians. Based on Sagie and Elizur's (1996) multifaceted approach, we distinguished personal values that are individual centered (i.e., associated with one's home, family, or work) from collective-centered values (i.e., associated with the religion, sports, or politics). The magnitude of the difference between both value types differs according to cultural orientation. As compared with Palestinians, we predicted that Canadians and Israelis would rank individual-centered values higher and collective-centered values lower. Data obtained from samples of Palestinians, Israelis, and Canadians supported this hypothesis.

  6. Different redox sensitivity of endoplasmic reticulum associated degradation clients suggests a novel role for disulphide bonds in secretory proteins.

    Science.gov (United States)

    Medraño-Fernandez, Iria; Fagioli, Claudio; Mezghrani, Alexandre; Otsu, Mieko; Sitia, Roberto

    2014-04-01

    To maintain proteostasis in the endoplasmic reticulum (ER), terminally misfolded secretory proteins must be recognized, partially unfolded, and dislocated to the cytosol for proteasomal destruction, in a complex process called ER-associated degradation (ERAD). Dislocation implies reduction of inter-chain disulphide bonds. When in its reduced form, protein disulphide isomerase (PDI) can act not only as a reductase but also as an unfoldase, preparing substrates for dislocation. PDI oxidation by Ero1 favours substrate release and transport across the ER membrane. Here we addressed the redox dependency of ERAD and found that DTT stimulates the dislocation of proteins with DTT-resistant disulphide bonds (i.e., orphan Ig-μ chains) but stabilizes a ribophorin mutant (Ri332) devoid of them. DTT promotes the association of Ri332, but not of Ig-µ, with PDI. This discrepancy may suggest that disulphide bonds in cargo proteins can be utilized to oxidize PDI, hence facilitating substrate detachment and degradation also in the absence of Ero1. Accordingly, Ero1 silencing retards Ri332 degradation, but has little if any effect on Ig-µ. Thus, some disulphides can increase the stability and simultaneously favour quality control of secretory proteins.

  7. Identification of an Isothiocyanate on the HypEF Complex Suggests a Route for Efficient Cyanyl-Group Channeling during [NiFe]-Hydrogenase Cofactor Generation.

    Directory of Open Access Journals (Sweden)

    Sven T Stripp

    Full Text Available [NiFe]-hydrogenases catalyze uptake and evolution of H2 in a wide range of microorganisms. The enzyme is characterized by an inorganic nickel/ iron cofactor, the latter of which carries carbon monoxide and cyanide ligands. In vivo generation of these ligands requires a number of auxiliary proteins, the so-called Hyp family. Initially, HypF binds and activates the precursor metabolite carbamoyl phosphate. HypF catalyzes removal of phosphate and transfers the carbamate group to HypE. In an ATP-dependent condensation reaction, the C-terminal cysteinyl residue of HypE is modified to what has been interpreted as thiocyanate. This group is the direct precursor of the cyanide ligands of the [NiFe]-hydrogenase active site cofactor. We present a FT-IR analysis of HypE and HypF as isolated from E. coli. We follow the HypF-catalyzed cyanation of HypE in vitro and screen for the influence of carbamoyl phosphate and ATP. To elucidate on the differences between HypE and the HypEF complex, spectro-electrochemistry was used to map the vibrational Stark effect of naturally cyanated HypE. The IR signature of HypE could ultimately be assigned to isothiocyanate (-N=C=S rather than thiocyanate (-S-C≡N. This has important implications for cyanyl-group channeling during [NiFe]-hydrogenase cofactor generation.

  8. Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis.

    Science.gov (United States)

    Christie, M; Jorissen, R N; Mouradov, D; Sakthianandeswaren, A; Li, S; Day, F; Tsui, C; Lipton, L; Desai, J; Jones, I T; McLaughlin, S; Ward, R L; Hawkins, N J; Ruszkiewicz, A R; Moore, J; Burgess, A W; Busam, D; Zhao, Q; Strausberg, R L; Simpson, A J; Tomlinson, I P M; Gibbs, P; Sieber, O M

    2013-09-26

    Biallelic protein-truncating mutations in the adenomatous polyposis coli (APC) gene are prevalent in sporadic colorectal cancer (CRC). Mutations may not be fully inactivating, instead producing WNT/β-catenin signalling levels 'just-right' for tumourigenesis. However, the spectrum of optimal APC genotypes accounting for both hits, and the influence of clinicopathological features on genotype selection remain undefined. We analysed 630 sporadic CRCs for APC mutations and loss of heterozygosity (LOH) using sequencing and single-nucleotide polymorphism microarrays, respectively. Truncating APC mutations and/or LOH were detected in 75% of CRCs. Most truncating mutations occurred within a mutation cluster region (MCR; codons 1282-1581) leaving 1-3 intact 20 amino-acid repeats (20AARs) and abolishing all Ser-Ala-Met-Pro (SAMP) repeats. Cancers commonly had one MCR mutation plus either LOH or another mutation 5' to the MCR. LOH was associated with mutations leaving 1 intact 20AAR. MCR mutations leaving 1 vs 2-3 intact 20AARs were associated with 5' mutations disrupting or leaving intact the armadillo-repeat domain, respectively. Cancers with three hits had an over-representation of mutations upstream of codon 184, in the alternatively spliced region of exon 9, and 3' to the MCR. Microsatellite unstable cancers showed hyper-mutation at MCR mono- and di-nucleotide repeats, leaving 2-3 intact 20AARs. Proximal and distal cancers exhibited different preferred APC genotypes, leaving a total of 2 or 3 and 0 to 2 intact 20AARs, respectively. In conclusion, APC genotypes in sporadic CRCs demonstrate 'fine-tuned' interdependence of hits by type and location, consistent with selection for particular residual levels of WNT/β-catenin signalling, with different 'optimal' thresholds for proximal and distal cancers.

  9. Three-dimensional preservation of cellular and subcellular structures suggests 1.6 billion-year-old crown-group red algae

    Science.gov (United States)

    Bengtson, Stefan; Sallstedt, Therese; Belivanova, Veneta; Whitehouse, Martin

    2017-01-01

    The ~1.6 Ga Tirohan Dolomite of the Lower Vindhyan in central India contains phosphatized stromatolitic microbialites. We report from there uniquely well-preserved fossils interpreted as probable crown-group rhodophytes (red algae). The filamentous form Rafatazmia chitrakootensis n. gen, n. sp. has uniserial rows of large cells and grows through diffusely distributed septation. Each cell has a centrally suspended, conspicuous rhomboidal disk interpreted as a pyrenoid. The septa between the cells have central structures that may represent pit connections and pit plugs. Another filamentous form, Denaricion mendax n. gen., n. sp., has coin-like cells reminiscent of those in large sulfur-oxidizing bacteria but much more recalcitrant than the liquid-vacuole-filled cells of the latter. There are also resemblances with oscillatoriacean cyanobacteria, although cell volumes in the latter are much smaller. The wider affinities of Denaricion are uncertain. Ramathallus lobatus n. gen., n. sp. is a lobate sessile alga with pseudoparenchymatous thallus, “cell fountains,” and apical growth, suggesting florideophycean affinity. If these inferences are correct, Rafatazmia and Ramathallus represent crown-group multicellular rhodophytes, antedating the oldest previously accepted red alga in the fossil record by about 400 million years. PMID:28291791

  10. Meta-analytic results of ethnic group differences in peer victimization.

    Science.gov (United States)

    Vitoroulis, Irene; Vaillancourt, Tracy

    2015-03-01

    Research on the prevalence of peer victimization across ethnicities indicates that no one group is consistently at higher risk. In the present two meta-analyses representing 692,548 children and adolescents (age 6-18 years), we examined ethnic group differences in peer victimization at school by including studies with (a) ethnic majority-minority group comparisons (k = 24), and (b) White and Black, Hispanic, Asian, and Aboriginal comparisons (k = 81). Methodological moderating effects (measure type, definition of bullying, publication type and year, age, and country) were examined in both analyses. Using Cohen's d, results indicated a null effect size for the ethnic majority-minority group comparison. Moderator analyses indicated that ethnic majority youth experienced more peer victimization than ethnic minorities in the US (d = .23). The analysis on multiple group comparisons between White and Black (d = .02), Hispanic (d = .08), Asian (d = .05), Aboriginal (d = -.02) and Biracial (d = -.05) groups indicated small effect sizes. Overall, results from the main and moderator analyses yielded small effects of ethnicity, suggesting that ethnicity assessed as a demographic variable is not an adequate indicator for addressing ethnic group differences in peer victimization. Although few notable differences were found between White and non-White groups regarding rates of peer victimization, certain societal and methodological limitations in the assessment of peer victimization may underestimate differences between ethnicities. Aggr. Behav. Aggr. Behav. 42:149-170, 2015. © 2014 Wiley Periodicals, Inc. © 2014 Wiley Periodicals, Inc.

  11. Population Analysis of Adverse Events in Different Age Groups Using Big Clinical Trials Data.

    Science.gov (United States)

    Luo, Jake; Eldredge, Christina; Cho, Chi C; Cisler, Ron A

    2016-10-17

    Understanding adverse event patterns in clinical studies across populations is important for patient safety and protection in clinical trials as well as for developing appropriate drug therapies, procedures, and treatment plans. The objective of our study was to conduct a data-driven population-based analysis to estimate the incidence, diversity, and association patterns of adverse events by age of the clinical trials patients and participants. Two aspects of adverse event patterns were measured: (1) the adverse event incidence rate in each of the patient age groups and (2) the diversity of adverse events defined as distinct types of adverse events categorized by organ system. Statistical analysis was done on the summarized clinical trial data. The incident rate and diversity level in each of the age groups were compared with the lowest group (reference group) using t tests. Cohort data was obtained from ClinicalTrials.gov, and 186,339 clinical studies were analyzed; data were extracted from the 17,853 clinical trials that reported clinical outcomes. The total number of clinical trial participants was 6,808,619, and total number of participants affected by adverse events in these trials was 1,840,432. The trial participants were divided into eight different age groups to support cross-age group comparison. In general, children and older patients are more susceptible to adverse events in clinical trial studies. Using the lowest incidence age group as the reference group (20-29 years), the incidence rate of the 0-9 years-old group was 31.41%, approximately 1.51 times higher (P=.04) than the young adult group (20-29 years) at 20.76%. The second-highest group is the 50-59 years-old group with an incidence rate of 30.09%, significantly higher (Pdata suggest that age-associated adverse events should be considered in planning, monitoring, and regulating clinical trials.

  12. Mangroves, hurricanes, and lightning strikes: Assessment of Hurricane Andrew suggests an interaction across two differing scales of disturbance

    Science.gov (United States)

    Smith, Thomas J.; Robblee, Michael B.; Wanless, Harold R.; Doyle, Thomas W.

    1994-01-01

    The track of Hurricane Andrew carried it across one of the most extensive mangrove for ests in the New World. Although it is well known that hurricanes affect mangrove forests, surprisingly little quantitative information exists concerning hurricane impact on forest structure, succession, species composition, and dynamics of mangrove-dependent fauna or on rates of eco-system recovery (see Craighead and Gilbert 1962, Roth 1992, Smith 1992, Smith and Duke 1987, Stoddart 1969).After Hurricane Andrew's passage across south Florida, we assessed the environmental damage to the natural resources of the Everglades and Biscayne National Parks. Quantitative data collected during subsequent field trips (October 1992 to July 1993) are also provided. We present measurements of initial tree mortality by species and size class, estimates of delayed (or continuing) tree mortality, and observations of geomorphological changes along the coast and in the forests that could influence the course of forest recovery. We discuss a potential interaction across two differing scales of disturbance within mangrove forest systems: hurricanes and lightning strikes.

  13. Intergenerational family solidarity: value differences between immigrant groups and generations.

    Science.gov (United States)

    Merz, Eva-Maria; Ozeke-Kocabas, Ezgi; Oort, Frans J; Schuengel, Carlo

    2009-06-01

    Although immigrants may be more dependent on their immediate family for support, they may also experience a wider generation-gap in values regarding intergenerational solidarity, because of processes of acculturation. Based on large scale survey data (N = 2,028), differences between first and second generation immigrants in values regarding intergenerational solidarity were examined among family members in the Netherlands with an immigration background from Turkey, Morocco, Suriname, and The Dutch Antilles. Using a multilevel analytic approach, effects of family and individual characteristics on values regarding intergenerational solidarity were tested, considering the perspectives of two generations. It was found that immigrants with Moroccan and Turkish backgrounds scored higher on values with respect to intergenerational family solidarity than immigrants stemming from Suriname and The Antilles. First generation immigrants placed higher values on family solidarity compared to second generation immigrants. Additionally, religious denomination was a significant predictor of higher values with respect to intergenerational family solidarity. Immigration and acculturation may create great strains in migrant families. Policies to support the fabric of intergenerational solidarity should consider ethnic and religious background and immigration history.

  14. Adequate dosing of micronutrients for different age groups in the life cycle.

    Science.gov (United States)

    Bienz, Denise; Cori, Hector; Hornig, Dietrich

    2003-09-01

    Many studies of micronutrient supplementation in developing countries have used single-nutrient supplements with either vitamins or minerals. However, people in these countries often suffer from multiple, rather than single, micronutrient deficiencies. The objective of this paper is to discuss the factors that go into determining the adequate dosing of vitamins and/or minerals for people of different ages. To elaborate on the adequacy of micronutrient doses in supplements, a model described by the US FNB was used, which calculates the difference between the mean observed intake for an individual and the estimated average requirement for a life stage and gender group. This model allows estimating the degree of confidence that a certain nutrient intake (from supplements and diet) is adequate. The US/Canadian DRI values have been used as the basis for these calculations, from which it can be concluded that a daily supplement of one RDA of each micronutrient is adequate to cover the personal requirements of all individuals in each respective age and gender group of the population, provided that 20 to 40% of an RDA is supplied by the diet--likely a realistic value for developing countries. DRI values vary significantly between different age groups, reflecting changing needs over a life cycle. With the objective of a supplement to be adequate and safe, the design of a one-for-all supplement covering all age groups is not realistic. Such a supplement would either underscore or surpass the required intake of some of the age groups. Additionally the dosage of certain micronutrients might exceed the upper level of intake for lower age groups. Therefore, it is suggested that three different supplements following the one RDA concept for all micronutrients be developed for research use in developing countries for the following age groups; 1 to 3 years, 4 to 13 years, and females > 14 years (excluding during pregnancy).

  15. Atomic resolution structure of a lysine-specific endoproteinase from Lysobacter enzymogenes suggests a hydroxyl group bound to the oxyanion hole.

    Science.gov (United States)

    Asztalos, Peter; Müller, Astrid; Hölke, Werner; Sobek, Harald; Rudolph, Markus G

    2014-07-01

    Lysobacter enzymogenes lysyl endoproteinase (LysC) is a trypsin-type serine protease with a high pH optimum that hydrolyses all Lys-Xaa peptide bonds. The high specificity of LysC renders it useful for biotechnological purposes. The K30R variant of a related lysyl endoproteinase from Achromobacter lyticus has favourable enzymatic properties that might be transferrable to LysC. To visualize structural differences in the substrate-binding sites, the crystal structures of wild-type and the K30R variant of LysC were determined. The mutation is located at a distance of 12 Å from the catalytic triad and subtly changes the surface properties of the substrate-binding site. The high pH optimum of LysC can be attributed to electrostatic effects of an aromatic Tyr/His stack on the catalytic aspartate and is a general feature of this enzyme subfamily. LysC crystals in complex with the covalent inhibitor N(α)-p-tosyl-lysyl chloromethylketone yielded data to 1.1 and 0.9 Å resolution, resulting in unprecedented precision of the active and substrate-binding sites for this enzyme subfamily. Error estimates on bond lengths and difference electron density indicate that instead of the expected oxyanion a hydroxyl group binds to the partially solvent-exposed oxyanion hole. Protonation of the alkoxide catalytic intermediate might be a recurring feature during serine protease catalysis.

  16. Testing Group Mean Differences of Latent Variables in Multilevel Data Using Multiple-Group Multilevel CFA and Multilevel MIMIC Modeling.

    Science.gov (United States)

    Kim, Eun Sook; Cao, Chunhua

    2015-01-01

    Considering that group comparisons are common in social science, we examined two latent group mean testing methods when groups of interest were either at the between or within level of multilevel data: multiple-group multilevel confirmatory factor analysis (MG ML CFA) and multilevel multiple-indicators multiple-causes modeling (ML MIMIC). The performance of these methods were investigated through three Monte Carlo studies. In Studies 1 and 2, either factor variances or residual variances were manipulated to be heterogeneous between groups. In Study 3, which focused on within-level multiple-group analysis, six different model specifications were considered depending on how to model the intra-class group correlation (i.e., correlation between random effect factors for groups within cluster). The results of simulations generally supported the adequacy of MG ML CFA and ML MIMIC for multiple-group analysis with multilevel data. The two methods did not show any notable difference in the latent group mean testing across three studies. Finally, a demonstration with real data and guidelines in selecting an appropriate approach to multilevel multiple-group analysis are provided.

  17. Relationship between Duffy blood groups genotypes and malaria infection in different ethnic groups of Choco- Colombia

    Directory of Open Access Journals (Sweden)

    Gonzalez, Lina

    2012-09-01

    Full Text Available Background: The negative homozygous condition for the Duffy blood group (Fy-/Fy- confers natural resistance to Plasmodium vivax infection. In this direction, studies carried out in Colombia are scarce.Objective: To describe the relationship between Duffy genotypes in three ethnic communities in La Italia (Chocó and malaria infection.Methodology: a descriptive, cross-sectional study in symptomatic and asymptomatic malaria subjects. Sample size : AfroAmerican, 73; Amerindian (Emberá, 74 and Mestizo, 171. Presence of Plasmodium infection was assessed by thick smear and the status of the Duffy gene by PCR and RFLP in order to identify the substitutions T-46C y A131G which origin the genotypes T/T, T/C , C/C y G/G, G/A, A/A.Results: Infection by Plasmodium was detected in 17% with 62% due to P. falciparum and 27% to P. vivax. Duffy genotypes were significantly associated to ethnicity (p=0,003. Individuals with the C/C, A/A diplotype were exclusively infected by P. falciparum, whereas other diplotypes were infected with either species. In the Amerindian and Mestizo populations, the frequency of the T-46 allele was 0,90-1,00, among Afrocolombians this was 0,50, equal to the C allele and with absence of heterozygous At locus 131, the highest frequency of the G allele was 0,30 in Amerindians and the A allele was 0,69 in Afrocolombians. Conclusions: In the Amerindian and mestizo populations studied, a predominance of the allele T-46 (FY+ was observed, but P. vivax was not the most common. Infection by P. vivax was out ruled in all FY- individuals.

  18. Diversification strategies in family and non-family groups: main differences according non-family group type

    Directory of Open Access Journals (Sweden)

    Alejandro Hernández Trasobares

    2016-01-01

    Full Text Available In the last decade, the interest for the study of ownership structure as a determinant of diversification arises. However, there is a lack of researches that analyze the influence of the nature of the ultimate owner in the level and type of diversification. Therefore, the objective of this paper is to analyze the diversification strategies used by the main Spanish business groups whose parent company is listed on the stock markets, and to study the differences between family and non-family business groups, considering in these last, the type of ultimate owner. In the study a sample of ninety-nine listed companies is used, where companies that constitute the business group are identified. In the paper are used as econometric methodologies the binomial logistic models and panel data models. The results show that family nature of business group positively influences in specialization and related diversification and negatively on unrelated diversification. Family groups differ most form those non-family groups where there is not a reference shareholder than can exercise effective control and ownership dispersion is higher, the groups referred as “non effective control”. The research allows further analysis of differences between family and non-family groups, considering the nature of the ultimate owner for non-family groups.

  19. Grouping normal type Ia supernovae by UV to optical color differences

    Energy Technology Data Exchange (ETDEWEB)

    Milne, Peter A. [University of Arizona, Steward Observatory, 933 North Cherry Avenue, Tucson, AZ 85719 (United States); Brown, Peter J. [George P. and Cynthia Woods Mitchell Institute for Fundamental Physics and Astronomy, Texas A. and M. University, Department of Physics and Astronomy, 4242 TAMU, College Station, TX 77843 (United States); Roming, Peter W. A. [Space Science and Engineering Division, Southwest Research Corporation, P.O. Drawer 28510, San Antonio, TX 78228-0510 (United States); Bufano, Filomena [Universidad Andres Bello, Departmento de Cincias Fisicas, Avda. Republica 220, Santiago (Chile); Gehrels, Neil, E-mail: pbrown@physics.tamu.edu [NASA-Goddard Space Flight Center, Astrophysics Science Division, Codes 660.1 and 662, Greenbelt, MD 20771 (United States)

    2013-12-10

    Observations of many Type Ia supernovae (SNe Ia) for multiple epochs per object with the Swift Ultraviolet Optical Telescope instrument have revealed that there exists order to the differences in the UV-optical colors of optically normal supernovae (SNe). We examine UV-optical color curves for 23 SNe Ia, dividing the SNe into four groups, and find that roughly one-third of 'NUV-blue' SNe Ia have bluer UV-optical colors than the larger 'NUV-red' group. Two minor groups are recognized, 'MUV-blue' and 'irregular' SNe Ia. While we conclude that the latter group is a subset of the NUV-red group, containing the SNe with the broadest optical peaks, we conclude that the 'MUV-blue' group is a distinct group. Separating into the groups and accounting for the time evolution of the UV-optical colors lowers the scatter in two NUV-optical colors (e.g., u – v and uvw1 – v) to the level of the scatter in b – v. This finding is promising for extending the cosmological utilization of SNe Ia into the NUV. We generate spectrophotometry of 33 SNe Ia and determine the correct grouping for each. We argue that there is a fundamental spectral difference in the 2900-3500 Å wavelength range, a region suggested to be dominated by absorption from iron-peak elements. The NUV-blue SNe Ia feature less absorption than the NUV-red SNe Ia. We show that all NUV-blue SNe Ia in this sample also show evidence of unburned carbon in optical spectra, whereas only one NUV-red SN Ia features that absorption line. Every NUV-blue event also exhibits a low gradient of the Si II λ6355 absorption feature. Many NUV-red events also exhibit a low gradient, perhaps suggestive that NUV-blue events are a subset of the larger low-velocity gradient group.

  20. Patients' experiences and expectations of general practice: a questionnaire study of differences by ethnic group

    Science.gov (United States)

    Ogden, Jane; Jain, Asha

    2005-01-01

    Background Research has highlighted variations in morbidity, mortality and health needs by ethnic group, and suggests that some ethnic groups may receive a poorer service. Aim To explore the impact of ethnic group on patients' experiences and expectations of their general practice consultation. Design of study Cross-sectional survey. Setting One general practice in a multicultural area of London. Method A total of 604 consecutive patients attending their general practice (response rate = 60.4%) who described their ethnic group as white British, black African, black African Caribbean or Vietnamese completed a measure relating to their experiences and their expectations of the general practice consultation in terms of treatment, communication, patients' agenda, patients' choice and doctor consistency. Results No differences were found for the black African or black African Caribbean patients. The Vietnamese patients reported better experiences of communication, more focus on their agenda and more attention to their choices than the white British patients. However, they also reported expecting lower levels of communication, less focus on their own agenda and reported wanting less GP consistency than the other ethnic groups. Conclusion Vietnamese patients state that they are receiving better standards of care in general practice than other ethnic groups. However, they also state that they expect less. This may illustrate a problem with assessing experiences of primary care. Higher scores of experience may not illustrate better consultations as such, but only better when compared with a lower level of initial expectation. A lower expectation is easier to fulfil. PMID:15904553

  1. Shallow crustal velocities and volcanism suggested from ambient noise studies using a dense broadband seismic network in the Tatun Volcano Group of Taiwan

    Science.gov (United States)

    Huang, Yu-Chih; Lin, Cheng-Horng; Kagiyama, Tsuneomi

    2017-07-01

    The Tatun Volcano Group (TVG) is situated adjacent to the Taipei metropolis and was active predominantly around 0.8-0.2 Ma (Pleistocene). Various recent lines of evidence suggest that the TVG is a potentially active volcano and that future volcanic eruptions cannot be ruled out. Geothermal activities are largely constrained to faults, but the relationship between volcanism and detailed velocity structures is not well understood. We analyzed ambient seismic noise of daily vertical components from 2014 using a dense seismic network of 40 broadband stations. We selected a 0.02° grid spacing to construct 2D and 3D shallow crustal phase velocity maps in the 0.5-3 s period band. Two S-wave velocity profiles transect Chishingshan (Mt. CS) in the shallow 3 km crust are further derived. The footwall of the Shanchiao Fault is dominated by low velocity, which may relate to Tertiary bedrock buried under andesitic lava flows dozens to hundreds of meters thick. The hanging wall of the Shanchiao Fault is the location of recent major volcanic activities. Low velocity zones in the southeast of Dayoukeng (DYK) may be interpreted as hydrothermal reservoirs or water-saturated Tertiary bedrock related to Cenozoic structures in the shallow crust. High velocities conspicuously dominate the east of the TVG, where the earliest stages of volcanism in the TVG are located, but where surface hydro-geothermal activities were absent in recent times. Between the Shanchiao Fault and Kanchiao Fault high velocities were detected, which converge below Mt. CS and may be related to early stages of magma conduits that gradually consolidated. These two faults may play a significant role with the TVG. The submarine volcanism adjacent to the Keelung coastline also requires further attention.

  2. Gender-stereotyping and cognitive sex differences in mixed- and same-sex groups.

    Science.gov (United States)

    Hirnstein, Marco; Coloma Andrews, Lisa; Hausmann, Markus

    2014-11-01

    Sex differences in specific cognitive abilities are well documented, but the biological, psychological, and sociocultural interactions that may underlie these differences are largely unknown. We examined within a biopsychosocial approach how gender stereotypes affect cognitive sex differences when adult participants were tested in mixed- or same-sex groups. A total of 136 participants (70 women) were allocated to either mixed- or same-sex groups and completed a battery of sex-sensitive cognitive tests (i.e., mental rotation, verbal fluency, perceptual speed) after gender stereotypes or gender-neutral stereotypes (control) were activated. To study the potential role of testosterone as a mediator for group sex composition and stereotype boost/threat effects, saliva samples were taken before the stereotype manipulation and after cognitive testing. The results showed the typical male and female advantages in mental rotation and verbal fluency, respectively. In general, men and women who were tested in mixed-sex groups and whose gender stereotypes had not been activated performed best. Moreover, a stereotype threat effect emerged in verbal fluency with reduced performance in gender stereotyped men but not women. Testosterone levels did not mediate the effects of group sex composition and stereotype threat nor did we find any relationship between testosterone and cognitive performance in men and women. Taken together, the findings suggest that an interaction of gender stereotyping and group sex composition affects the performance of men and women in sex-sensitive cognitive tasks. Mixed-sex settings can, in fact, increase cognitive performance as long as gender-stereotyping is prevented.

  3. Food prices and consumer demand: differences across income levels and ethnic groups.

    Directory of Open Access Journals (Sweden)

    Cliona Ni Mhurchu

    Full Text Available BACKGROUND: Targeted food pricing policies may improve population diets. To assess their effects on inequalities, it is important to determine responsiveness to price changes across income levels and ethnic groups. OBJECTIVE: Our goal was to estimate price elasticity (PE values for major commonly consumed food groups in New Zealand, by income and ethnicity. PE values represent percentage change in demand associated with 1% change in price of that good (own-PE or another good (cross-PE. DESIGN: We used food expenditure data from national household economic surveys in 2007/08 and 2009/10 and Food Price Index data from 2007 and 2010. Adopting an Almost Ideal Demand System approach, own-PE and cross-PE estimates were derived for 24 food categories, household income quintiles, and two ethnic groups (Māori and non-Māori. RESULTS: Own-PE estimates (with two exceptions ranged from -0.44 to -1.78. Cross-PE estimates were generally small; only 31% of absolute values were greater than 0.10. Excluding the outlier 'energy drinks', nine of 23 food groups had significantly stronger own-PEs for the lowest versus highest income quintiles (average regression-based difference across food groups -0.30 (95% CI -0.62 to 0.02. Six own-PEs were significantly stronger among Māori; the average difference for Māori: non-Māori across food groups was -0.26 (95% CI -0.52 to 0.00. CONCLUSIONS: Food pricing policies have potential to improve population diets. The greater sensitivity of low-income households and Māori to price changes suggests the beneficial effects of such policies on health would be greatest for these groups.

  4. Food prices and consumer demand: differences across income levels and ethnic groups.

    Science.gov (United States)

    Ni Mhurchu, Cliona; Eyles, Helen; Schilling, Chris; Yang, Qing; Kaye-Blake, William; Genç, Murat; Blakely, Tony

    2013-01-01

    Targeted food pricing policies may improve population diets. To assess their effects on inequalities, it is important to determine responsiveness to price changes across income levels and ethnic groups. Our goal was to estimate price elasticity (PE) values for major commonly consumed food groups in New Zealand, by income and ethnicity. PE values represent percentage change in demand associated with 1% change in price of that good (own-PE) or another good (cross-PE). We used food expenditure data from national household economic surveys in 2007/08 and 2009/10 and Food Price Index data from 2007 and 2010. Adopting an Almost Ideal Demand System approach, own-PE and cross-PE estimates were derived for 24 food categories, household income quintiles, and two ethnic groups (Māori and non-Māori). Own-PE estimates (with two exceptions) ranged from -0.44 to -1.78. Cross-PE estimates were generally small; only 31% of absolute values were greater than 0.10. Excluding the outlier 'energy drinks', nine of 23 food groups had significantly stronger own-PEs for the lowest versus highest income quintiles (average regression-based difference across food groups -0.30 (95% CI -0.62 to 0.02)). Six own-PEs were significantly stronger among Māori; the average difference for Māori: non-Māori across food groups was -0.26 (95% CI -0.52 to 0.00). Food pricing policies have potential to improve population diets. The greater sensitivity of low-income households and Māori to price changes suggests the beneficial effects of such policies on health would be greatest for these groups.

  5. Do racial and ethnic group differences in performance on the MCAT exam reflect test bias?

    Science.gov (United States)

    Davis, Dwight; Dorsey, J Kevin; Franks, Ronald D; Sackett, Paul R; Searcy, Cynthia A; Zhao, Xiaohui

    2013-05-01

    The Medical College Admission Test (MCAT) is a standardized examination that assesses fundamental knowledge of scientific concepts, critical reasoning ability, and written communication skills. Medical school admission officers use MCAT scores, along with other measures of academic preparation and personal attributes, to select the applicants they consider the most likely to succeed in medical school. In 2008-2011, the committee charged with conducting a comprehensive review of the MCAT exam examined four issues: (1) whether racial and ethnic groups differ in mean MCAT scores, (2) whether any score differences are due to test bias, (3) how group differences may be explained, and (4) whether the MCAT exam is a barrier to medical school admission for black or Latino applicants. This analysis showed that black and Latino examinees' mean MCAT scores are lower than white examinees', mirroring differences on other standardized admission tests and in the average undergraduate grades of medical school applicants. However, there was no evidence that the MCAT exam is biased against black and Latino applicants as determined by their subsequent performance on selected medical school performance indicators. Among other factors which could contribute to mean differences in MCAT performance, whites, blacks, and Latinos interested in medicine differ with respect to parents' education and income. Admission data indicate that admission committees accept majority and minority applicants at similar rates, which suggests that medical students are selected on the basis of a combination of attributes and competencies rather than on MCAT scores alone.

  6. Salivary Alpha Amylase Activity in Human Beings of Different Age Groups Subjected to Psychological Stress

    National Research Council Canada - National Science Library

    Sahu, Gopal K; Upadhyay, Seema; Panna, Shradha M

    2014-01-01

    ... in different age groups is least studied. This article reports the activity of sAA in human subjects of different age groups subjected to psychological stress induced through stressful video clip...

  7. Examining the role of different age groups, and of vaccination during the 2012 Minnesota pertussis outbreak.

    Science.gov (United States)

    Worby, Colin J; Kenyon, Cynthia; Lynfield, Ruth; Lipsitch, Marc; Goldstein, Edward

    2015-08-17

    There is limited information on the roles of different age groups during pertussis outbreaks. Little is known about vaccine effectiveness against pertussis infection (both clinically apparent and subclinical), which is different from effectiveness against reportable pertussis disease, with the former influencing the impact of vaccination on pertussis transmission in the community. For the 2012 pertussis outbreak in Minnesota, we estimated odds ratios for case counts in pairs of population groups before vs. after the epidemic's peak. We found children aged 11-12y, 13-14y and 8-10y experienced the greatest rates of depletion of susceptible individuals during the outbreak's ascent, with all ORs for each of those age groups vs. groups outside this age range significantly above 1, with the highest ORs for ages 11-12y. Receipt of the fifth dose of DTaP was associated with a decreased relative role during the outbreak's ascent compared to non-receipt [OR 0.16 (0.01, 0.84) for children aged 5, 0.13 (0.003, 0.82) for ages 8-10y, indicating a protective effect of DTaP against pertussis infection. No analogous effect of Tdap was detected. Our results suggest that children aged 8-14y played a key role in propagating this outbreak. The impact of immunization with Tdap on pertussis infection requires further investigation.

  8. Molecular dynamics re-refinement of two different small RNA loop structures using the original NMR data suggest a common structure.

    Science.gov (United States)

    Henriksen, Niel M; Davis, Darrell R; Cheatham, Thomas E

    2012-08-01

    Restrained molecular dynamics simulations are a robust, though perhaps underused, tool for the end-stage refinement of biomolecular structures. We demonstrate their utility-using modern simulation protocols, optimized force fields, and inclusion of explicit solvent and mobile counterions-by re-investigating the solution structures of two RNA hairpins that had previously been refined using conventional techniques. The structures, both domain 5 group II intron ribozymes from yeast ai5γ and Pylaiella littoralis, share a nearly identical primary sequence yet the published 3D structures appear quite different. Relatively long restrained MD simulations using the original NMR restraint data identified the presence of a small set of violated distance restraints in one structure and a possibly incorrect trapped bulge nucleotide conformation in the other structure. The removal of problematic distance restraints and the addition of a heating step yielded representative ensembles with very similar 3D structures and much lower pairwise RMSD values. Analysis of ion density during the restrained simulations helped to explain chemical shift perturbation data published previously. These results suggest that restrained MD simulations, with proper caution, can be used to "update" older structures or aid in the refinement of new structures that lack sufficient experimental data to produce a high quality result. Notable cautions include the need for sufficient sampling, awareness of potential force field bias (such as small angle deviations with the current AMBER force fields), and a proper balance between the various restraint weights.

  9. What Do Students Think about Group Work in Business Education? An Investigation into the Benefits, Challenges, and Student-Suggested Solutions

    Science.gov (United States)

    Lee, Seung Hwan Mark; Smith, Donna; Sergueeva, Ksenia

    2016-01-01

    The authors sought to gain insight on how students view group learning and development as part of their business education experience. Specifically, the authors categorize benefits and challenges using S. A. Wheelan's (2005) integrated model of group development. Additionally, they investigate (from the students' perspective) best practices that…

  10. What Do Students Think about Group Work in Business Education? An Investigation into the Benefits, Challenges, and Student-Suggested Solutions

    Science.gov (United States)

    Lee, Seung Hwan Mark; Smith, Donna; Sergueeva, Ksenia

    2016-01-01

    The authors sought to gain insight on how students view group learning and development as part of their business education experience. Specifically, the authors categorize benefits and challenges using S. A. Wheelan's (2005) integrated model of group development. Additionally, they investigate (from the students' perspective) best practices that…

  11. 团购网站可持续发展研究%Research on the Problems in Group Purchase Websites and Development Suggestions

    Institute of Scientific and Technical Information of China (English)

    张涛

    2012-01-01

    作为一种新兴的电子商务模式,团购网站在国内迅速发展,但在实际运行中其问题日趋明显。本论文通过对网络团购的现状分析入手,浅谈其中存在的问题并提出几点对策。%As a new consumption patterns and business model,group purchase can realize consumer,business,group purchase websites and society in multi-win-win situation.Now,group purchase websites have become the main form of network group purchase.But because of the lack of corresponding supervision mechanism and the low cost of establishing and operating group purchase websites can be a problem.This assay just focous on the solution of it.

  12. Perspective Taking Explains Gender Differences in Late Adolescents' Attitudes Toward Disadvantaged Groups.

    Science.gov (United States)

    Smith, Colin Tucker; Shepperd, James A; Miller, Wendi A; Graber, Julia A

    2016-07-01

    Adolescents' attitudes toward disadvantaged groups are surprisingly understudied. What we know from these few studies is that adolescents' attitudes tend to become more favorable over time and that adolescent girls display more favorable attitudes than do adolescent boys. However, researchers have not offered explanations for why these effects occur. We proposed that changes in social-cognitive abilities that accompany adolescent development increase perspective taking and that the increased perspective taking facilitates more favorable attitudes toward disadvantaged groups. Because girls develop social-cognitive abilities earlier than boys, girls should show greater perspective taking and thus more positive attitudes toward disadvantaged groups than should boys. Importantly, we propose that these more positive attitudes are explained better by perspective taking than by gender. Participants were late adolescents (n = 803, 53.3 % female, ages 15-19) from high schools in north-central Florida (United States) participating in an ongoing, multi-wave study. Participants completed a measure of perspective-taking and reported their attitudes toward three disadvantaged groups (Black, gay, and poor people) during their third year of high school and, again, 6 months later during their fourth year of high school. Our findings provided strong support for our theorizing. Girls generally reported warmer attitudes than did boys toward disadvantaged groups, with the gender differences in warmth tending to diminish across time. Similarly, girls were higher than boys in perspective-taking abilities at both time points, although boys increased over time whereas girls did not. Crucially, perspective taking mediated observed gender differences in attitudes, suggesting that perspective taking is a mechanism for improving attitudes toward disadvantaged groups during late adolescence.

  13. Understanding childhood asthma in focus groups: perspectives from mothers of different ethnic backgrounds

    Directory of Open Access Journals (Sweden)

    McKenzie Sheila

    2001-09-01

    Full Text Available Abstract Background Diagnosing childhood asthma is dependent upon parental symptom reporting but there are problems in the use of words and terms. The purpose of this study was to describe and compare understandings of childhood 'asthma' by mothers from three different ethnic backgrounds who have no personal experience of diagnosing asthma. A better understanding of parents' perceptions of an illness by clinicians should improve communication and management of the illness. Method Sixty-six mothers living in east London describing their ethnic backgrounds as Bangladeshi, white English and black Caribbean were recruited to 9 focus groups. Discussion was semi-structured. Three sessions were conducted with each ethnic group. Mothers were shown a video clip of a boy with audible wheeze and cough and then addressed 6 questions. Sessions were recorded and transcribed verbatim. Responses were compared within and between ethnic groups. Results Each session, and ethnic group overall, developed a particular orientation to the discussion. Some mothers described the problem using single signs, while others imitated the sound or made comparisons to other illnesses. Hereditary factors were recognised by some, although all groups were concerned with environmental triggers. Responses about what to do included 'normal illness' strategies, use of health services and calls for complementary treatment. All groups were concerned about using medication every day. Expectations about the quality of life were varied, with recognition that restrictions may be based on parental beliefs about asthma, rather than asthma itself. Conclusion Information from these focus groups suggests mothers know a great deal about childhood asthma even though they have no personal experience of it. Knowledge of how mothers from these ethnic backgrounds perceive asthma may facilitate doctor – patient communication with parents of children experiencing breathing difficulties.

  14. Do fly parasites of bats and their hosts coevolve?speciation in Trichobius phyllostomae group (Diptera, Streblidae and their hosts (Chiroptera, Phyllostomidae suggests that they do not

    Directory of Open Access Journals (Sweden)

    Gustavo Graciolli

    2012-12-01

    Full Text Available We examined whether, like many parasite-host systems of coevolution, a group of obligate parasitic bat flies (Trichobius phyllostomae Kessel and related species cospeciate with their hosts. We first did a cladistic analysis of the T. phyllostomae group and combined that analysis with a phylogenetic hypothesis from the literature for the Stenodermatinae bats. The cladistic analysis included, as outgroups, one species from each morphological group and complex of Trichobius Gervais, and one species from the following genera: Paratrichobius Miranda-Ribeiro, Megistopoda Macquart, Megistapophysys Dick & Wenzel, Neotrichobius Wenzel & Aitken, Speiseria Kessel and Strebla Wiedemann. The cladogram was rooted with a species of Strebla in the subfamily Streblinae. One cladogram was obtained and which found Trichobius to be polyphyletic. The phylogenetic hypothesis as follows: (Paratrichobius, (Neotrichobius, (Megistopoda, Megistapophysis is the sister-group of the phyllostomae group and the following relationships within the ingroup, (((T. vampyropis Wenzel, Trichobius sp. 2 ((T. hispidus Wenzel, T. petersoni Wenzel ((Trichobius sp. 1 (T. phyllostomae, T. brennani Wenzel. When we compared phylogenies through historical association analyses, cospeciation was uncommon, while host-switching was more common and better explained the association between the phyllostomae group and their bat hosts.

  15. Population biology of intestinal enterococcus isolates from hospitalized and nonhospitalized individuals in different age groups.

    Science.gov (United States)

    Tedim, Ana P; Ruiz-Garbajosa, Patricia; Corander, Jukka; Rodríguez, Concepción M; Cantón, Rafael; Willems, Rob J; Baquero, Fernando; Coque, Teresa M

    2015-03-01

    The diversity of enterococcal populations from fecal samples from hospitalized (n = 133) and nonhospitalized individuals (n = 173) of different age groups (group I, ages 0 to 19 years; group II, ages 20 to 59 years; group III, ages ≥60 years) was analyzed. Enterococci were recovered at similar rates from hospitalized and nonhospitalized persons (77.44% to 79.77%) of all age groups (75.0% to 82.61%). Enterococcus faecalis and Enterococcus faecium were predominant, although seven other Enterococcus species were identified. E. faecalis and E. faecium (including ampicillin-resistant E. faecium) colonization rates in nonhospitalized persons were age independent. For inpatients, E. faecalis colonization rates were age independent, but E. faecium colonization rates (particularly the rates of ampicillin-resistant E. faecium colonization) significantly increased with age. The population structure of E. faecium and E. faecalis was determined by superimposing goeBURST and Bayesian analysis of the population structure (BAPS). Most E. faecium sequence types (STs; 150 isolates belonging to 75 STs) were linked to BAPS groups 1 (22.0%), 2 (31.3%), and 3 (36.7%). A positive association between hospital isolates and BAPS subgroups 2.1a and 3.3a (which included major ampicillin-resistant E. faecium human lineages) and between community-based ampicillin-resistant E. faecium isolates and BAPS subgroups 1.2 and 3.3b was found. Most E. faecalis isolates (130 isolates belonging to 58 STs) were grouped into 3 BAPS groups, BAPS groups 1 (36.9%), 2 (40.0%), and 3 (23.1%), with each one comprising widespread lineages. No positive associations with age or hospitalization were established. The diversity and dynamics of enterococcal populations in the fecal microbiota of healthy humans are largely unexplored, with the available knowledge being fragmented and contradictory. The study offers a novel and comprehensive analysis of enterococcal population landscapes and suggests that E. faecium

  16. [Detection of influenza B virus antibodies in different age groups using hemagglutination inhibition tests].

    Science.gov (United States)

    Sonuvar, S; Kocabeyoğlu, O; Emekdaş

    1991-01-01

    Antibody levels against influenza B virus were investigated by using hemagglutination-inhibition (HA-I) tests in 402 sera obtained from different age groups. Hemagglutination antigens were obtained by production of influenza B virus (B/Singapur/LLC 6201) in trypsinized Madin Darby Bovine Kidney (MDBK) cell cultured and they were used in tests. In 355 out of 402 sera (88.3%) antibodies against influenza B virus were detected at titers varying between 1/20 and 1/1280. However in 47 sera (11.7%) no antibodies were detected at 1/20 titer. High titers of antibody (1/640-1/1280) were not detected in none of the sera obtained from an age group between 1 and 14. However high titer antibodies were detected in 15.6% of the sera from an age group between 26 and 35, in the 17.3% of the sera from a group above 50 years of age. Our findings suggest that the increase in the rates of seropositivity against influenza B virus depends on getting older and, that the infections by this virus may be widely seen in our country.

  17. Arbuscular mycorrhizal fungal phylogenetic groups differ in affecting host plants along heavy metal levels.

    Science.gov (United States)

    He, Lei; Yang, Haishui; Yu, Zhenxing; Tang, Jianjun; Xu, Ligen; Chen, Xin

    2014-10-01

    Arbuscular mycorrhizal fungi (AMF) are important components of soil microbial communities, and play important role in plant growth. However, the effects of AMF phylogenetic groups (Glomeraceae and non-Glomeraceae) on host plant under various heavy metal levels are not clear. Here we conducted a meta-analysis to compare symbiotic relationship between AMF phylogenetic groups (Glomeraceae and non-Glomeraceae) and host plant functional groups (herbs vs. trees, and non-legumes vs. legumes) at three heavy metal levels. In the meta-analysis, we calculate the effect size (ln(RR)) by taking the natural logarithm of the response ratio of inoculated to non-inoculated shoot biomass from each study. We found that the effect size of Glomeraceae increased, but the effect size of non-Glomeraceae decreased under high level of heavy metal compared to low level. According to the effect size, both Glomeraceae and non-Glomeraceae promoted host plant growth, but had different effects under various heavy metal levels. Glomeraceae provided more benefit to host plants than non-Glomeraceae did under heavy metal condition, while non-Glomeraceae provided more benefit to host plants than Glomeraceae did under no heavy metal. AMF phylogenetic groups also differed in promoting plant functional groups under various heavy metal levels. Interacting with Glomeraceae, herbs and legumes grew better than trees and non-legumes did under high heavy metal level, while trees and legumes grew better than herbs and non-legumes did under medium heavy metal level. Interacting with non-Glomeraceae, herbs and legumes grew better than trees and non-legumes did under no heavy metal. We suggested that the combination of legume with Glomeraceae could be a useful way in the remediation of heavy metal polluted environment.

  18. Group decisions and individual differences: route fidelity predicts flight leadership in homing pigeons (Columba livia).

    Science.gov (United States)

    Freeman, Robin; Mann, Richard; Guilford, Tim; Biro, Dora

    2011-02-23

    How social-living animals make collective decisions is currently the subject of intense scientific interest, with increasing focus on the role of individual variation within the group. Previously, we demonstrated that during paired flight in homing pigeons, a fully transitive leadership hierarchy emerges as birds are forced to choose between their own and their partner's habitual routes. This stable hierarchy suggests a role for individual differences mediating leadership decisions within homing pigeon pairs. What these differences are, however, has remained elusive. Using novel quantitative techniques to analyse habitual route structure, we show here that leadership can be predicted from prior route-following fidelity. Birds that are more faithful to their own route when homing alone are more likely to emerge as leaders when homing socially. We discuss how this fidelity may relate to the leadership phenomenon, and propose that leadership may emerge from the interplay between individual route confidence and the dynamics of paired flight.

  19. Identification of copy number variants defining genomic differences among major human groups.

    Directory of Open Access Journals (Sweden)

    Lluís Armengol

    Full Text Available BACKGROUND: Understanding the genetic contribution to phenotype variation of human groups is necessary to elucidate differences in disease predisposition and response to pharmaceutical treatments in different human populations. METHODOLOGY/PRINCIPAL FINDINGS: We have investigated the genome-wide profile of structural variation on pooled samples from the three populations studied in the HapMap project by comparative genome hybridization (CGH in different array platforms. We have identified and experimentally validated 33 genomic loci that show significant copy number differences from one population to the other. Interestingly, we found an enrichment of genes related to environment adaptation (immune response, lipid metabolism and extracellular space within these regions and the study of expression data revealed that more than half of the copy number variants (CNVs translate into gene-expression differences among populations, suggesting that they could have functional consequences. In addition, the identification of single nucleotide polymorphisms (SNPs that are in linkage disequilibrium with the copy number alleles allowed us to detect evidences of population differentiation and recent selection at the nucleotide variation level. CONCLUSIONS: Overall, our results provide a comprehensive view of relevant copy number changes that might play a role in phenotypic differences among major human populations, and generate a list of interesting candidates for future studies.

  20. Ten Thousand Voices on Marine Climate Change in Europe: Different Perceptions among Demographic Groups and Nationalities

    Directory of Open Access Journals (Sweden)

    Paul J. Buckley

    2017-07-01

    Full Text Available Over the past few decades, substantial funding has been directed toward improving scientific understanding and management of impacts of climate change in the marine environment. Following concerns that the key messages from these studies were not reaching the public, a comprehensive opinion poll of 10,000 European citizens in 10 countries was conducted to establish levels of awareness, concern, and trust among different demographic groups (by age, gender, proximity to the coast and nationalities. Citizens exhibited varying levels of self-declared “informedness” and concern. Citizens from Germany, Italy and Spain claimed to be the most informed on marine climate change issues; those from Czech Republic, Netherlands and Estonia claimed to be least informed. Respondents were least aware of ocean acidification and most aware of melting sea ice, pollution and overfishing. Citizens of Italy suggested that they were generally most concerned about marine climate change issues. Respondents from coastal areas claimed to be both more informed and more concerned than those living inland, as did females and older age groups (54–64 years. European citizens obtain information about climate change in the seas and ocean from different sources, particularly television and the internet. Trust in the various media sources varies among countries and demographic groups. Television is trusted most in Estonia, Germany and Ireland and least in France. The internet is trusted most in Italy, Czech Republic and Estonia, but least in France and the United Kingdom. 18–24 year olds are the biggest users of the internet, but trust this source less than older age groups. Academic scientists or those working for environmental NGOs are trusted more than scientists working for government or industry. Citizens from France are more trusting of industry than any other country polled. In terms of policy actions, most respondents highlighted mitigation measures as opposed to

  1. Light interception in species with different functional groups coexisting in moorland plant communities.

    Science.gov (United States)

    Kamiyama, Chiho; Oikawa, Shimpei; Kubo, Takuya; Hikosaka, Kouki

    2010-11-01

    Competition for light is one of the most essential mechanisms affecting species composition. It has been suggested that similar light acquisition efficiency (Φ(mass), absorbed photon flux per unit aboveground mass) may contribute to species coexistence in multi-species communities. On the other hand, it is known that traits related with light acquisition vary among functional groups. We studied whether Φ(mass) was similar among species with different functional groups coexisting in moorland communities. We conducted stratified clipping in midsummer when the stand biomass reached a maximum. Light partitioning among species was estimated using a model accounting for both direct and diffuse light. Evergreen species were found to have a significantly lower Φ(mass) than deciduous species, which resulted from their lower absorbed photon flux per unit leaf area and lower specific leaf area. Shrubs had a smaller leaf mass fraction, but their Φ(mass) was not lower than that of herbs because they had a higher leaf position due to the presence of wintering stems. Species with vertical leaves had a higher Φ(mass) than those with horizontal leaves despite vertical leaves being a decided disadvantage in terms of light absorption. This higher Φ(mass) was achieved by a greater leaf height in species with vertical leaves. Our results clearly demonstrate that light acquisition efficiency was different among the functional groups. However, the trend observed is not necessarily the same as that expected based on prior knowledge, suggesting that disadvantages in some traits for light acquisition efficiency are partly compensated for by other traits.

  2. Food intake of individuals with and without diabetes across different countries and ethnic groups

    Science.gov (United States)

    Nöthlings, U; Boeing, H; Maskarinec, G; Sluik, D; Teucher, B; Kaaks, R; Tjønneland, A; Halkjaer, J; Dethlefsen, C; Overvad, K; Amiano, P; Toledo, E; Bendinelli, B; Grioni, S; Tumino, R; Sacerdote, C; Mattiello, A; Beulens, JWJ; Iestra, JA; Spijkerman, AMW; van der A, DL; Nilsson, P; Sonestedt, E; Rolandsson, O; Franks, PW; Vergnaud, A-C; Romaguera, D; Norat, T; Kolonel, LN

    2011-01-01

    Background/Objectives Given the importance of nutrition therapy in diabetes management, we hypothesized that food intake differs between individuals with and without diabetes. We investigated this hypothesis in two large prospective studies including different countries and ethnic groups. Methods Study populations were the EPIC (European Prospective Investigation into Cancer and Nutrition)-Study and the Multiethnic Cohort Study (MEC). Dietary intake was assessed via food frequency questionnaires, and calibrated using 24h-recall information for the EPIC-Study. Only confirmed self-reports of diabetes at cohort entry were included: 6192 diabetes patients in EPIC and 13 776 in the MEC. For the cross-sectional comparison of food intake and lifestyle variables at baseline, individuals with and without diabetes were matched 1:1 on sex, age in five year categories, BMI in 2.5 kg/m2 categories, and country. Results Higher intake of softdrinks (by 13 and 44% in the EPIC and MEC), and lower consumption of sweets, juice, wine, and beer (>10% difference) were observed in participants with diabetes compared to those without. Consumption of vegetables, fish and meat was slightly higher in individuals with diabetes in both studies, but the differences were less than 10%. Findings were more consistent across different ethnic groups than countries, but generally showed largely similar patterns. Conclusions Although diabetes patients are expected to undergo nutritional education, we found only small differences in dietary behavior in comparison to cohort members without diabetes. These findings suggest that emphasis on education is needed to improve the current behaviors in order to assist in the prevention of complications. PMID:21346715

  3. On the properties of compact groups identified in different photometric bands

    CERN Document Server

    Taverna, Antonela; Zandivarez, Ariel; Joray, Francisco; Kanagusuku, Maria Jose

    2016-01-01

    Historically, compact group catalogues vary not only in their identification algorithms and selection functions, but also in their photometric bands. Differences between compact group catalogues have been reported. However, it is difficult to assess the impact of the photometric band in these differences given the variety of identification algorithms. We used the mock lightcone built by Henriques et al. (2012) to identify and compare compact groups in three different photometric bands: $K$, $r$, and $u$. We applied the same selection functions in the three bands, and found that compact groups in the u-band look the smallest in projection, the difference between the two brightest galaxies is the largest in the K-band, while compact groups in the r-band present the lowest compactness. We also investigated the differences between samples when galaxies are selected only in one particular band (pure compact groups) and those that exist regardless the band in which galaxies were observed (common compact groups). We...

  4. Infrared Thermography to Evaluate Heat Tolerance in Different Genetic Groups of Lambs

    Directory of Open Access Journals (Sweden)

    Concepta McManus

    2015-07-01

    Full Text Available Heat stress is considered a limiting factor for sheep production. We used information from physiological characteristics linked to heat tolerance to determine whether infrared thermography temperatures were able to separate groups of animals and determine the most important variables in this differentiation. Forty-eight four-month-old male lambs from eight genetic groups were used. Physiological (rectal temperature–RT, heart rate–HR, respiratory rate–RR and blood traits, infrared thermography temperatures, heat tolerance indices, body measurements, weight and carcass traits were measured. Statistical analyses included variance, correlations, factor, discrimination and regression. Observing the correlations between physiological characteristics (RT, RR and HR with temperatures measured by infrared thermography, regions for further studies should include the mean temperature of flank, nose and rump. Results show that there are strong relationships between thermograph measurements and RR, RT and HR in lambs, which are suggested to be directly correlated with heat tolerance capacity of the different genetic groups evaluated in this study. The assessment of body surface temperature measured by the thermograph could be used as a noninvasive tool to assess heat tolerance of the animals.

  5. Infrared Thermography to Evaluate Heat Tolerance in Different Genetic Groups of Lambs

    Science.gov (United States)

    McManus, Concepta; Bianchini, Eliandra; Paim, Tiago do Prado; de Lima, Flavia Gontijo; Braccini Neto, José; Castanheira, Marlos; Esteves, Geisa Isilda Ferreira; Cardoso, Caio Cesar; Dalcin, Vanessa Calderaro

    2015-01-01

    Heat stress is considered a limiting factor for sheep production. We used information from physiological characteristics linked to heat tolerance to determine whether infrared thermography temperatures were able to separate groups of animals and determine the most important variables in this differentiation. Forty-eight four-month-old male lambs from eight genetic groups were used. Physiological (rectal temperature–RT, heart rate–HR, respiratory rate–RR) and blood traits, infrared thermography temperatures, heat tolerance indices, body measurements, weight and carcass traits were measured. Statistical analyses included variance, correlations, factor, discrimination and regression. Observing the correlations between physiological characteristics (RT, RR and HR) with temperatures measured by infrared thermography, regions for further studies should include the mean temperature of flank, nose and rump. Results show that there are strong relationships between thermograph measurements and RR, RT and HR in lambs, which are suggested to be directly correlated with heat tolerance capacity of the different genetic groups evaluated in this study. The assessment of body surface temperature measured by the thermograph could be used as a noninvasive tool to assess heat tolerance of the animals. PMID:26193274

  6. Comparison of 12-step groups to mutual help alternatives for AUD in a large, national study: Differences in membership characteristics and group participation, cohesion, and satisfaction.

    Science.gov (United States)

    Zemore, Sarah E; Kaskutas, Lee Ann; Mericle, Amy; Hemberg, Jordana

    2017-02-01

    the 12-step alternatives showed equivalent activity involvement and higher levels of satisfaction and cohesion, compared to 12-step members. Results suggest differences across 12-step groups and their alternatives that may be relevant when advising clients on a choice of mutual help group. Meanwhile, findings for high levels of participation, satisfaction, and cohesion among members of the mutual help alternatives suggest promise for these groups in addressing addiction problems. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. Several Suggestions about the Construction of the Group of Medical Engineering%对医学工程技术队伍建设的几点建议

    Institute of Scientific and Technical Information of China (English)

    毛英军; 谢立旗; 王明刚

    2012-01-01

    本文通过对部队和地方12所三级甲等医院医学工程部门的人员编制、业务工作等情况的调研,就如何加强医学工程技术队伍建设、促进医疗设备质量安全控制工作、提高保障能力提出 几点建议.%After researching the circumstances of dept of medical equipment about the staff and the scope of business from 12 tertiary A class hospital in recent years. There are some suggestions about how to wind the level of the medical engineering team, promoting the control of medical equipment quality and safety and improving security ability.

  8. Facial resemblance to emotions: group differences, impression effects, and race stereotypes.

    Science.gov (United States)

    Zebrowitz, Leslie A; Kikuchi, Masako; Fellous, Jean-Marc

    2010-02-01

    The authors used connectionist modeling to extend previous research on emotion overgeneralization effects. Study 1 demonstrated that neutral expression male faces objectively resemble angry expressions more than female faces do, female faces objectively resemble surprise expressions more than male faces do, White faces objectively resemble angry expressions more than Black or Korean faces do, and Black faces objectively resemble happy and surprise expressions more than White faces do. Study 2 demonstrated that objective resemblance to emotion expressions influences trait impressions even when statistically controlling possible confounding influences of attractiveness and babyfaceness. It further demonstrated that emotion overgeneralization is moderated by face race and that racial differences in emotion resemblance contribute to White perceivers' stereotypes of Blacks and Asians. These results suggest that intergroup relations may be strained not only by cultural stereotypes but also by adaptive responses to emotion expressions that are overgeneralized to groups whose faces subtly resemble particular emotions.

  9. Prevalence of vaginitis in different age groups among females in Greece.

    Science.gov (United States)

    Sianou, Argiri; Galyfos, George; Moragianni, Dimitra; Baka, Stavroula

    2017-08-01

    Patients with vaginitis were classified into four groups: Group A (prepubertal under-aged females); Group B (pubertal under-aged females); Group C (reproductive age adult females); Group D (postmenopausal adult females). All vaginal specimens underwent microscopy, amine testing, Gram staining and culturing. Overall, 163 patients were included (33, 14, 81 and 35 patients, respectively). The most common infection was bacterial vaginosis (BV), followed by Ureaplasma infection, aerobic vaginitis (AV) and candidiasis. The most common AV-associated organism was Escherichia coli and the most common BV-associated organism was Gardnerella vaginalis. AV was more frequent in Group A, BV in Group C and Ureaplasma infections in Groups C/D. Decreased lactobacilli concentrations were associated with BV in fertile patients (Groups B-C). Although presentation of vaginitis is similar among females of different age in Greece, type and prevalence of pathogens differ. Normal vaginal flora changes are associated with higher risk of vaginitis in specific age groups. Impact Statement The worldwide incidence of reproductive tract infections has been increasing, with specific pathogens being associated with significant risk of morbidity and complications. However, literature data on the distribution of such infections in different age groups is limited. Therefore, the aim of this study was to provide data on the prevalence and causes of vaginitis in adult and non-adult females of all ages. This study has shown that although presentation of vaginitis is similar among females of different age groups and menstrual status in Greece, type and prevalence of responsible pathogens are different among groups. Changes in normal vaginal flora seem to be associated with higher risk of vaginitis in specific age-groups as well. These findings could contribute in adjusting diagnostic and therapeutic strategies for each age group according to the prevailing pathogens. Further research on antibiotic

  10. Effect of Different Types of Small-Group Activities on Students' Conversations

    Science.gov (United States)

    Young, Krista K.; Talanquer, Vicente

    2013-01-01

    Teaching reform efforts in chemistry education often involve engaging students in small-group activities of different types. This study focused on the analysis of how activity type affected the nature of group conversations. In particular, we analyzed the small-group conversations of students enrolled in a chemistry course for nonscience majors.…

  11. Fluorescently tuned nitrogen-doped carbon dots from carbon source with different content of carboxyl groups

    Directory of Open Access Journals (Sweden)

    Hao Wang

    2015-08-01

    Full Text Available In this study, fluorescent nitrogen-doped carbon dots (NCDs were tuned via varying the sources with different number of carboxyl groups. Owing to the interaction between amino and carboxyl, more amino groups conjugate the surface of the NCDs by the source with more carboxyl groups. Fluorescent NCDs were tuned via varying the sources with different content of carboxyl groups. Correspondingly, the nitrogen content, fluorescence quantum yields and lifetime of NCDs increases with the content of carboxyl groups from the source. Furthermore, cytotoxicity assay and cell imaging test indicate that the resultant NCDs possess low cytotoxicity and excellent biocompatibility.

  12. Fluorescently tuned nitrogen-doped carbon dots from carbon source with different content of carboxyl groups

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Hao; Wang, Yun; Dai, Xiao; Zou, Guifu, E-mail: kqzhang@suda.edu.cn, E-mail: zouguifu@suda.edu.cn [College of Physics, Optoelectronics and Energy and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215006 (China); Gao, Peng; Zhang, Ke-Qin, E-mail: kqzhang@suda.edu.cn, E-mail: zouguifu@suda.edu.cn; Du, Dezhuang [National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123 (China); Guo, Jun [Testing and Analysis Center, Soochow University, Suzhou 215123 (China)

    2015-08-01

    In this study, fluorescent nitrogen-doped carbon dots (NCDs) were tuned via varying the sources with different number of carboxyl groups. Owing to the interaction between amino and carboxyl, more amino groups conjugate the surface of the NCDs by the source with more carboxyl groups. Fluorescent NCDs were tuned via varying the sources with different content of carboxyl groups. Correspondingly, the nitrogen content, fluorescence quantum yields and lifetime of NCDs increases with the content of carboxyl groups from the source. Furthermore, cytotoxicity assay and cell imaging test indicate that the resultant NCDs possess low cytotoxicity and excellent biocompatibility.

  13. Difference in susceptibility to malaria between two sympatric ethnic groups in Mali.

    Science.gov (United States)

    Dolo, Amagana; Modiano, David; Maiga, Boubacar; Daou, Modibo; Dolo, Guimogo; Guindo, Hamadoun; Ba, Mamadou; Maiga, Hama; Coulibaly, Drissa; Perlman, Hedvig; Blomberg, Marita Troye; Touré, Yeya Tiemoko; Coluzzi, Mario; Doumbo, Ogobara

    2005-03-01

    We compared malaria indicators among sympatric groups to study human heterogeneities in the response to Plasmodium falciparum malaria infection. Four cross-sectional surveys and two longitudinal surveys in two sympatric ethnic groups (Dogon and Fulani) in Mali were carried out from 1998 to 2000. Spleen and parasite rates were evaluated during the cross-sectional surveys and disease incidence was assessed during longitudinal surveys. In spite of similar sociocultural factors and entomologic inoculation rates between ethnic groups, the Fulani had a significantly higher spleen enlargement rate, lower parasite rate, and were less affected by the disease than the Dogon group, whose frequency of hemoglobin C was higher than that recorded among the Fulani group. The Fulani group had significantly higher levels of IgG and IgE against crude malaria antigen than the Dogon group, suggesting a role of anti-malaria antibodies in the immune protection seen in this group.

  14. Intestinal parasitic infections in different groups of immunocompromised patients in Kashan and Qom cities, central Iran.

    Science.gov (United States)

    Rasti, Sima; Hassanzadeh, Malihe; Hooshyar, Hossein; Momen-Heravi, Mansooreh; Mousavi, Seyed Gholam Abbas; Abdoli, Amir

    Intestinal parasitic infections (IPIs) are important causes of morbidity and mortality in patients with immunocompromising conditions. The aim of this study was to determine the prevalence of IPIs in different groups of immunocompromised patients, including hemodialysis patients (HD), renal transplant recipients (RTR), cancer and HIV/AIDS patients in comparison with healthy individuals in two central cities of Iran (Kashan and Qom). In this case-control study, the stool samples of 135 HD, 50 RTR, 60 cancer patients, 20 HIV/AIDS patients and 120 healthy subjects were tested using direct-smear, formol-ether concentration, Ziehl-Neelsen staining and Agar plate method. The overall infection rate was 11.7% (31/265) in patient groups and 0% (0/120) in the control group. The frequency of parasites was 25% in HIV/AIDS patients, 11.9% (16/135) in HD, 12.0% (6/50) in RTR and 6.7% (4/60) in cancer patients. Blastocystis hominis (4.2%) and Giardia lamblia (3.0%) were the most prevalent parasites in patient groups. The infection rate was significantly higher in male (17.6%) than female (5.4%) patients (p = .002), but no statistically significant association was observed according to the age and educational levels. This study showed a high prevalence of IPIs in immunocompromised patients. The results of this study suggest that periodic stool examinations for screening of IPIs should be included as a part of routine medical care in these patients.

  15. The disease burden across different ethnic groups in Amsterdam, the Netherlands, 2011-2030.

    Science.gov (United States)

    Ikram, Umar Z; Kunst, Anton E; Lamkaddem, Majda; Stronks, Karien

    2014-08-01

    Current disease burden estimates do not provide evidence across different ethnic groups. This study aims to assess the disease burden as measured by the disability-adjusted life years (DALYs) for six ethnic groups in Amsterdam, the Netherlands, for 2011 and 2030. The DALYs were calculated by combining three components: disease-/sex-/age-specific DALYs per person; disease-specific relative risks (RRs) by ethnicity; and sex-/age-specific population sizes by ethnicity in Amsterdam in 2011 and 2030. Disease-specific DALYs were derived from the National Institute of Public Health. The RRs were obtained through a systematic review of studies published in 1997-2008. The population figures were gathered from the Statistics Netherlands and municipality of Amsterdam. The findings suggest that cardiovascular diseases and anxiety and depressive disorders dominate disease burden in all ethnic groups in 2011 and 2030. In most of the non-Western ethnic minorities, diabetes mellitus is the strongest contributor to the disease burden. The total disease burden will increase more strongly in non-Western ethnic minorities than ethnic Dutch. The 2030 disease burden is estimated to be highest among Surinamese and Antilleans. In ethnic minorities, diabetes plays an important role in the disease burden, and the total disease burden will grow stronger than ethnic Dutch, resulting in a higher total disease burden for some ethnic groups in 2030. We encourage researchers to estimate the disease burden by ethnicity so that health priorities can be set in the fields of policy, health care and research. © The Author 2013. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  16. A study on biochemical differences among five different groups of rice striped stem borer Chilo suppressalis Walker (Lepidoptera: Pyralidae

    Directory of Open Access Journals (Sweden)

    A Zibaee

    2008-02-01

    Full Text Available Identification of biodiversity in different rice striped stem borer (Chilo supprressalis populations is very important to adopt suitable integrated pest management procedures. Larvae were collected from five different regions in north of Iran including Gourabzarmikh (Go, Sheikhmahaleh (Sh, Rasht (Ra, Amol (Am and Babol (Ba. Activity levels of five enzymes including alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, lactate dehydrogenase and alpha-amylase were evaluated in 4th instar larvae. In addition, five non-enzymatic compounds such as glucose, cholesterol, total protein, uric acid and urea were also measured. Amount of measured compounds showed significant differences in all groups except for alanine aminotransferase and aspartate aminotransferase. Hierarchical agglomerative clustering under UPGMA model demonstrated that Ba population had the most genetic distance and was separated from other groups. In the second group, Go population had the most genetic distance from others and two groups of Ra and Sh had the least genetic distances.

  17. Short term memory development : Differences in serial position curves between age groups and latent classes

    NARCIS (Netherlands)

    Koppenol, G.V.; Bouwmeester, S.; Vermunt, J.K.

    2014-01-01

    In studies on the development of cognitive processes, children are often grouped based on their ages before analyzing the data. After the analysis, the differences between age groups are interpreted as developmental differences. We argue that this approach is problematic because the variance in

  18. Measurement Error Correction Formula for Cluster-Level Group Differences in Cluster Randomized and Observational Studies

    Science.gov (United States)

    Cho, Sun-Joo; Preacher, Kristopher J.

    2016-01-01

    Multilevel modeling (MLM) is frequently used to detect cluster-level group differences in cluster randomized trial and observational studies. Group differences on the outcomes (posttest scores) are detected by controlling for the covariate (pretest scores) as a proxy variable for unobserved factors that predict future attributes. The pretest and…

  19. Gender and Ethnic Group Differences on the GMAT Analytical Writing Assessment.

    Science.gov (United States)

    Bridgeman, Brent; McHale, Frederick

    Gender and ethnic group differences on the Analytical Writing Assessment that is part of the Graduate Management Admissions Test were evaluated. Data from the first operational administration for 36,583 examinees in October 1994 were used. Standardized differences from the White male reference group were computed separately for men and women in…

  20. Sex differences in general intelligence: a psychometric investigation of group differences in mean and variability as measured by the Raven's Standard Progressive Matrices

    OpenAIRE

    Savage-McGlynn, Emily

    2011-01-01

    Approved hardbound copy has subtitle "a psychometric investigation of group differences in mean and variability as measured by the Raven's Standard Progressive Matrices Plus" Researchers and the general public alike continue to debate ‘which is the smarter sex?’ Research to date suggests that males outperform females, females outperform males, while others find no differences in mean or variance. These inconsistent results are thought to occur for two reasons. First, studies rely on opport...

  1. What Lies Beneath: Sub-Articular Long Bone Shape Scaling in Eutherian Mammals and Saurischian Dinosaurs Suggests Different Locomotor Adaptations for Gigantism

    OpenAIRE

    2013-01-01

    Eutherian mammals and saurischian dinosaurs both evolved lineages of huge terrestrial herbivores. Although significantly more saurischian dinosaurs were giants than eutherians, the long bones of both taxa scale similarly and suggest that locomotion was dynamically similar. However, articular cartilage is thin in eutherian mammals but thick in saurischian dinosaurs, differences that could have contributed to, or limited, how frequently gigantism evolved. Therefore, we tested the hypothesis tha...

  2. Research the image of Samara city by students of the different professional groups

    OpenAIRE

    Lubov Davydkina

    2012-01-01

    The article presents results of the research of psychological areas in structure of an image of city of different professional groups: reveals value of psychological zoning of city space during structuring of an image of city. The author partitions and describes psychological areas and criteria of zoning of a group image of Samara city; compares psychological areas of different professional groups, describes the structure of psychological area, reveals the concept of a psy...

  3. Can dietary factors explain differences in serum cholesterol profiles among different ethnic groups (Chinese, Malays and Indians) in Singapore?

    NARCIS (Netherlands)

    Deurenberg-Yap, M.; Li, T.; Tan, W.L.; Staveren, van W.A.; Suok Chai Chew,; Deurenberg, P.

    2001-01-01

    In Singapore. there exists differences in risk factors for coronary heart disease among the three main ethnic groups: Chinese, Malays and Indians. This study aimed to investigate if differences in dietary intakes of fat, types of fat, cholesterol, fruits, vegetables and grain foods could explain the

  4. Can dietary factors explain differences in serum cholesterol profiles among different ethnic groups (Chinese, Malays and Indians) in Singapore?

    NARCIS (Netherlands)

    Deurenberg-Yap, M.; Li, T.; Tan, W.L.; Staveren, van W.A.; Suok Chai Chew,; Deurenberg, P.

    2001-01-01

    In Singapore. there exists differences in risk factors for coronary heart disease among the three main ethnic groups: Chinese, Malays and Indians. This study aimed to investigate if differences in dietary intakes of fat, types of fat, cholesterol, fruits, vegetables and grain foods could explain the

  5. Extending the cereus group genomics to putative food-bornepathogens of different toxicity

    Energy Technology Data Exchange (ETDEWEB)

    Lapidus, Alla; Goltsman, Eugene; Auger, Sandrine; Galleron,Nathalie; Segurens, Beatrice; Dossat, Carole; Land, Miriam L.; Broussole,Veronique; Brillard, Julien; Guinebretiere, Marie-Helene; Sanchis,Vincent; Nguen-the, Christophe; Lereclus, Didier; Richardson, Paul; Winker, Patrick; Weissenbach, Jean; Ehrlich, S.Dusko; Sorokin, Alexei

    2006-08-24

    The cereus group represents sporulating soil bacteriacontaining pathogenic strains which may cause diarrheic or emetic foodpoisoning outbreaks. Multiple locus sequence typing revealed a presencein natural samples of these bacteria of about thirty clonal complexes.Application of genomic methods to this group was however biased due tothe major interest for representatives closely related to B. anthracis.Albeit the most important food-borne pathogens were not yet defined,existing dataindicate that they are scattered all over the phylogenetictree. The preliminary analysis of the sequences of three genomesdiscussed in this paper narrows down the gaps in our knowledge of thecereus group. The strain NVH391-98 is a rare but particularly severefood-borne pathogen. Sequencing revealed that the strain must be arepresentative of a novel bacterial species, for which the name Bacilluscytotoxis is proposed. This strain has a reduced genome size compared toother cereus group strains. Genome analysis revealed absence of sigma Bfactor and the presence of genes encoding diarrheic Nhe toxin, notdetected earlier. The strain B. cereus F837/76 represents a clonalcomplex close to that of B. anthracis. Including F837/76, three such B.cereus strains had been sequenced. Alignment of genomes suggests that B.anthracis is their common ancestor. Since such strains often emerge fromclinical cases, they merit a special attention. The third strain, KBAB4,is a typical psychrotrophe characteristic to unbiased soil communities.Phylogenic studies show that in nature it is the most active group interms of gene exchange. Genomic sequence revealed high presence ofextra-chromosomal genetic material (about 530 kb) that may account forthis phenomenon. Genes coding Nhe-like toxin were found on a big plasmidin this strain. This may indicate a potential mechanism of toxicityspread from the psychrotrophic strain community. The results of thisgenomic work and ecological compartments of different strains incite

  6. Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity

    Energy Technology Data Exchange (ETDEWEB)

    Lapidus, Alla L. [U.S. Department of Energy, Joint Genome Institute; Goltsman, Eugene [U.S. Department of Energy, Joint Genome Institute; Auger, Sandrine [Genetique Microbienne; Galleron, Nathalie [Genetique Microbienne; Segurens, Beatrice [Center National Sequencage, F-91057 Evry, France; Simon, Jorg [Johann Wolfgang Goethe University, Frankfurt am Main, Germany; Dossat, Carole [Genoscope/Centre National de la Recherche Scientifique-Unite Mixte de Recherche; Land, Miriam L [ORNL; Broussolle, Veronique [Securite et Qualite des Produits d' Origine Vegetale; Brillard, Julien [Securite et Qualite des Produits d' Origine Vegetale; Guinebretiere, Marie-Helene [Securite et Qualite des Produits d' Origine Vegetale; Sanchis, Vincent [Genetique Microbienne; Nguen-the, Christophe [Securite et Qualite des Produits d' Origine Vegetale; Lereclus, Didier [Genetique Microbienne; Richardson, P M [U.S. Department of Energy, Joint Genome Institute; Wincker, Patrick [Genoscope/Centre National de la Recherche Scientifique-Unite Mixte de Recherche; Weissenbach, Jean [Genoscope/Centre National de la Recherche Scientifique-Unite Mixte de Recherche; Ehrlich, Dusko [Genetique Microbienne; Sorokin, Alexei [Genetique Microbienne

    2008-01-01

    The Bacillus cereus group represents sporulating soil bacteria containing pathogenic strains which may cause diarrheic or emetic food poisoning outbreaks. Multiple locus sequence typing revealed a presence in natural samples of these bacteria of about 30 clonal complexes. Application of genomic methods to this group was however biased due to the major interest for representatives closely related to Bacillus anthracis. Albeit the most important food-borne pathogens were not yet defined, existing data indicate that they are scattered all over the phylogenetic tree. The preliminary analysis of the sequences of three genomes discussed in this paper narrows down the gaps in our knowledge of the B. cereus group. The strain NVH391-98 is a rare but particularly severe food-borne pathogen. Sequencing revealed that the strain should be a representative of a novel bacterial species, for which the name Bacillus cytotoxis or Bacillus cytotoxicus is proposed. This strain has a reduced genome size compared to other B. cereus group strains. Genome analysis revealed absence of sigma B factor and the presence of genes encoding diarrheic Nhe toxin, not detected earlier. The strain B. cereus F837/76 represents a clonal complex close to that of B. anthracis. Including F837/76, three such B. cereus strains had been sequenced. Alignment of genomes suggests that B. anthracis is their common ancestor. Since such strains often emerge from clinical cases, they merit a special attention. The third strain, KBAB4, is a typical facultative psychrophile generally found in soil. Phylogenic studies show that in nature it is the most active group in terms of gene exchange. Genomic sequence revealed high presence of extra-chromosomal genetic material (about 530 kb) that may account for this phenomenon. Genes coding Nhe-like toxin were found on a big plasmid in this strain. This may indicate a potential mechanism of toxicity spread from the psychrophile strain community. The results of this genomic

  7. Clinical Implications for Muscle Strength Differences in Women of Different Age and Racial Groups: The WIN Study

    Science.gov (United States)

    Trudelle-Jackson, Elaine; Ferro, Emerenciana; Morrow, James R.

    2011-01-01

    Background Reduction in muscle strength is strongly associated with functional decline in women, and women with lower quadriceps strength adjusted for body weight are more likely to develop knee osteoarthritis. Objective To compare body weight--adjusted strength among women of different age/racial groups. Study Design Cross-sectional study of muscle strength in 918 women aged 20--83 (M ± SD = 52 ± 13). Methods An orthopedic examination was conducted including measurement of handgrip and lower extremity strength (hip abductors/external rotators, knee flexors/extensors). Data were grouped into young (20--39 years, n = 139), middle (40--54 years, n = 300), and older (55+ years, n = 424) ages for white (n = 699) and African American (AA) (n = 164) women. Means and standard deviations for strength adjusted for body weight were calculated for each age and racial group and compared using 2-way multivariate analysis of variance and post hoc tests. Results No significant age-by-race interaction (P = .092) but significant main effects for age and race (P < .001). Pairwise comparisons revealed significant differences in knee extensor and flexor strength between all age groups. For grip and hip external rotator strength, significant differences were found between the middle and older groups. Differences in hip abductor strength were found between the young and middle-aged groups. AA women had lower strength than white women in all muscle groups (P < .05) except hip external rotators. Conclusions Strength decreased with age in all muscle groups but magnitude of decrease varied by muscle. Strengthening programs should target different muscles, depending on a woman's age and race. PMID:21666779

  8. Clinical presentation of infective endocarditis caused by different groups of non-beta haemolytic streptococci.

    Science.gov (United States)

    Nilson, B; Olaison, L; Rasmussen, M

    2016-02-01

    Streptococci are common causes of infective endocarditis (IE) and matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has provided a practical tool for their species determination. We aimed to investigate if particular groups of non-beta heamolytic streptococci were associated with IE or to specific presentations thereof. The Swedish Registry of Infective Endocarditis was used to identify cases of IE caused by streptococci and a local database to identify cases of streptococcal bacteremia. The bacteria were grouped using MALDI-TOF MS and the clinical characteristics of IE caused by different groups were compared. We identified a group of 201 streptococcal IE isolates: 18 isolates belonged to the anginosus, 19 to the bovis, 140 to the mitis, 17 to the mutans, and seven to the salivarius groups. The mitis and mutans groups were significantly more common and the anginosus group less common among IE cases as compared to all cause bacteremia. Patients infected with the bovis group isolates were older, had more cardiac devices, and had more commonly prosthetic valve IE compared to IE caused by streptococci of the other groups. Twenty-one percent of patients needed surgery, and in-hospital mortality was 8% with no significant differences between the groups. Grouping of non-beta haemolytic streptococci using MALDI-TOF MS can provide a basis for decision-making in streptococcal bacteremia. IE caused by bovis group isolates have clinical characteristics distinguishing them from IE caused by other groups of Streptococcus.

  9. Metabolism of Oxycodone in Human Hepatocytes from Different Age Groups and Prediction of Hepatic Plasma Clearance

    Science.gov (United States)

    Korjamo, Timo; Tolonen, Ari; Ranta, Veli-Pekka; Turpeinen, Miia; Kokki, Hannu

    2012-01-01

    Oxycodone is commonly used to treat severe pain in adults and children. It is extensively metabolized in the liver in adults, but the maturation of metabolism is not well understood. Our aim was to study the metabolism of oxycodone in cryopreserved human hepatocytes from different age groups (3 days, 2 and 5 months, 4 years, adult pool) and predict hepatic plasma clearance of oxycodone using these data. Oxycodone (0.1, 1, and 10 μM) was incubated with hepatocytes for 4 h, and 1 μM oxycodone also with CYP3A inhibitor ketoconazole (1 μM). Oxycodone and noroxycodone concentrations were determined at several time points with liquid chromatography–mass spectrometry. In vitro clearance of oxycodone was used to predict hepatic plasma clearance, using the well-stirred model and published physiological parameters. Noroxycodone was the major metabolite in all batches and ketoconazole inhibited the metabolism markedly in most cases. A clear correlation between in vitro oxycodone clearance and CYP3A4 activity was observed. The predicted hepatic plasma clearances were typically much lower than the published median total plasma clearance from pharmacokinetic studies. The data suggests that there are no children-specific metabolites of oxycodone. Moreover, CYP3A activity seems to be the major determinant in metabolic clearance of oxycodone regardless of age group or individual variability in hepatocyte batches. PMID:22291644

  10. Unique transcriptomic response to sepsis is observed among patients of different age groups.

    Science.gov (United States)

    Raymond, Steven L; López, María Cecilia; Baker, Henry V; Larson, Shawn D; Efron, Philip A; Sweeney, Timothy E; Khatri, Purvesh; Moldawer, Lyle L; Wynn, James L

    2017-01-01

    Sepsis is a major cause of morbidity and mortality, especially at the extremes of age. To understand the human age-specific transcriptomic response to sepsis, a multi-cohort, pooled analysis was conducted on adults, children, infants, and neonates with and without sepsis. Nine public whole-blood gene expression datasets (636 patients) were employed. Age impacted the transcriptomic host response to sepsis. Gene expression from septic neonates and adults was more dissimilar whereas infants and children were more similar. Neonates showed reductions in inflammatory recognition and signaling pathways compared to all other age groups. Likewise, adults demonstrated decreased pathogen sensing, inflammation, and myeloid cell function, as compared to children. This may help to explain the increased incidence of sepsis-related organ failure and death in adults. The number of dysregulated genes in septic patients was proportional to age and significantly differed among septic adults, children, infants, and neonates. Overall, children manifested a greater transcriptomic intensity to sepsis as compared to the other age groups. The transcriptomic magnitude for adults and neonates was dramatically reduced as compared to children and infants. These findings suggest that the transcriptomic response to sepsis is age-dependent, and diagnostic and therapeutic efforts to identify and treat sepsis will have to consider age as an important variable.

  11. Group differences in the legitimization of inequality: Questioning the role of social dominance orientation.

    Science.gov (United States)

    Pehrson, Samuel; Carvacho, Héctor; Sibley, Chris G

    2017-03-01

    Social dominance orientation (SDO) is conceived as an individual's level of support for group-based hierarchy in general that causes support for more specific group hierarchies. According to social dominance theory, group differences in SDO underpin ideological and behavioural group differences related to specific group hierarchies. Using representative 5-year longitudinal panel data from New Zealand (N = 3,384), we test whether SDO mediates effects of sex and ethnicity on legitimizing myths (LMs) relating to gender and ethnic hierarchy over time. The SDO mediation hypothesis is supported in the case of hostile sexism. However, it is unsupported in the case of benevolent sexism and LMs relating to ethnic hierarchy, where there was no cross-lagged effect of SDO. Moreover, being in the dominant ethnic group is associated with more legitimization of ethnic hierarchy but less legitimization of gender hierarchy, which is inconsistent with the notion of a general orientation underpinning group differences in legitimation. There was mixed evidence for a reverse path whereby specific LMs mediate group differences in SDO across time. We argue for the need to find alternative ways to theorize ideological consensus and difference between groups.

  12. The influence of climatic seasonality on the diversity of different tropical pollinator groups.

    Directory of Open Access Journals (Sweden)

    Stefan Abrahamczyk

    Full Text Available Tropical South America is rich in different groups of pollinators, but the biotic and abiotic factors determining the geographical distribution of their species richness are poorly understood. We analyzed the species richness of three groups of pollinators (bees and wasps, butterflies, hummingbirds in six tropical forests in the Bolivian lowlands along a gradient of climatic seasonality and precipitation ranging from 410 mm to 6250 mm. At each site, we sampled the three pollinator groups and their food plants twice for 16 days in both the dry and rainy seasons. The richness of the pollinator groups was related to climatic factors by linear regressions. Differences in species numbers between pollinator groups were analyzed by Wilcoxon tests for matched pairs and the proportion in species numbers between pollinator groups by correlation analyses. Species richness of hummingbirds was most closely correlated to the continuous availability of food, that of bees and wasps to the number of food plant species and flowers, and that of butterflies to air temperature. Only the species number of butterflies differed significantly between seasons. We were not able to find shifts in the proportion of species numbers of the different groups of pollinators along the study gradient. Thus, we conclude that the diversity of pollinator guilds is determined by group-specific factors and that the constant proportions in species numbers of the different pollinator groups constitute a general pattern.

  13. The Influence of Climatic Seasonality on the Diversity of Different Tropical Pollinator Groups

    Science.gov (United States)

    Abrahamczyk, Stefan; Kluge, Jürgen; Gareca, Yuvinka; Reichle, Steffen; Kessler, Michael

    2011-01-01

    Tropical South America is rich in different groups of pollinators, but the biotic and abiotic factors determining the geographical distribution of their species richness are poorly understood. We analyzed the species richness of three groups of pollinators (bees and wasps, butterflies, hummingbirds) in six tropical forests in the Bolivian lowlands along a gradient of climatic seasonality and precipitation ranging from 410 mm to 6250 mm. At each site, we sampled the three pollinator groups and their food plants twice for 16 days in both the dry and rainy seasons. The richness of the pollinator groups was related to climatic factors by linear regressions. Differences in species numbers between pollinator groups were analyzed by Wilcoxon tests for matched pairs and the proportion in species numbers between pollinator groups by correlation analyses. Species richness of hummingbirds was most closely correlated to the continuous availability of food, that of bees and wasps to the number of food plant species and flowers, and that of butterflies to air temperature. Only the species number of butterflies differed significantly between seasons. We were not able to find shifts in the proportion of species numbers of the different groups of pollinators along the study gradient. Thus, we conclude that the diversity of pollinator guilds is determined by group-specific factors and that the constant proportions in species numbers of the different pollinator groups constitute a general pattern. PMID:22073268

  14. What could critical mathematics education mean for different groups of students?

    DEFF Research Database (Denmark)

    Skovsmose, Ole

    2016-01-01

    In this article I consider what critical mathematics education could mean for different groups of students. Much discussion and research has addressed students at social risk. My point, however, is that critical mathematics education concerns other groups as well: for example, students in comfort......In this article I consider what critical mathematics education could mean for different groups of students. Much discussion and research has addressed students at social risk. My point, however, is that critical mathematics education concerns other groups as well: for example, students...... in comfortable positions, blind students, elderly students, "other" students, university students, as well as engineering students. By considering such different groups of students, I will show that "reading and writing the world with mathematics" opens towards a range of different interpretations, which brings...

  15. Theories of Suggestion.

    Science.gov (United States)

    Brown, W

    1928-02-01

    The word "suggestion" has been used in educational, scientific and medical literature in slightly different senses. In psychological medicine the use of suggestion has developed out of the earlier use of hypnotic influence.Charcot defined hypnosis as an artificial hysteria, Bernheim as an artificially increased suggestibility. The two definitions need to be combined to give an adequate account of hypnosis. Moreover, due allowance should be made for the factors of dissociation and of rapport in hypnotic phenomena.The relationships between dissociation, suggestibility, and hypnotizability.Theories of suggestion propounded by Pierre Janet, Freud, McDougall, Pawlow and others. Ernest Jones's theory of the nature of auto-suggestion. Janet explains suggestion in terms of ideo-motor action in which the suggested idea, because of the inactivity of competing ideas, produces its maximum effect. Freud explains rapport in terms of the sex instinct "inhibited in its aim" (transference) and brings in his distinction of "ego" and "ego-ideal" (or "super-ego") to supplement the theory. Jones explains auto-suggestion in terms of narcissism. McDougall explains hypnotic suggestion in terms of the instinct of self-abasement. But different instincts may supply the driving power to produce suggestion-effects in different circumstances. Such instincts as those of self-preservation (fear) and gregariousness may play their part. Auto-suggestion as a therapeutic factor is badly named. It supplements, but does not supplant the will, and makes complete volition possible.

  16. Holter monitoring for syncope: diagnostic yield in different patient groups and impact on device implantation.

    Science.gov (United States)

    Kühne, M; Schaer, B; Moulay, N; Sticherling, C; Osswald, S

    2007-12-01

    Holter monitoring is routinely used in patients referred for the evaluation of syncope, but its diagnostic value in different patient groups is unclear, as is its impact on device implantation (pacemaker or cardioverter-defibrillator). To determine the diagnostic yield of Holter monitoring in the routine evaluation of syncope, and its impact on subsequent device implantation. Retrospective record review. We reviewed all Holter studies in patients referred with syncope between 2000 and 2005. Strict criteria were applied to determine whether a study was diagnostic. The diagnostic value of Holter monitoring (overall and in five subgroups: age, gender, structural heart disease, ejection fraction, medication) and its impact on the implantation of devices, were determined. Of 4877 Holter studies, 826 were performed in patients with syncope (age 72 +/- 15 years): 71 (8.6%) were considered to explain the syncope. Structural heart disease, ejection fraction and age were significant predictors of a diagnostic study (all p Holter did not explain their syncope, after mean 7 months, whereas 45 patients (5.4%) received a pacemaker based on the Holter results (p = 0.32). The overall diagnostic yield of Holter monitoring in the evaluation of syncope was 8.6%, with dramatic differences between subgroups. Our data suggest that the impact of Holter monitoring on device implantation is generally overestimated.

  17. Cause and Causality in Daycare Research: An Investigation of Group Differences in Swedish Child Care.

    Science.gov (United States)

    Wessels, Holger; Lamb, Michael E.; Hwang, Carl-Philip

    1996-01-01

    Illustrates problems facing researchers trying to demonstrate causal relationships between types of nonparental care and differences between groups of Swedish children. Argues that efforts must be made to validate and interpret differences that are found. Indicates ways to avoid misinterpretation of differences that are attributable to…

  18. Variations of Weight of Thyroid Gland in Different Age and Sex Groups of Bangladeshi Cadavers.

    Science.gov (United States)

    Sultana, R; Khan, M K; Mannan, S; Asaduzzaman, S M; Sultana, M; Sultana, J; Farzana, T; Epsi, E Z; Wahed, F; Sultana, S

    2015-07-01

    A cross sectional descriptive study was designed to find out the difference in weight of the thyroid gland of Bangladeshi people in relation to age and sex. The present study was performed on 70 post mortem human thyroid gland (35 of male and 35 of female) collected from the morgue in the Department of Forensic Medicine, Mymensingh Medical College, Mymensingh by purposive sampling technique. The specimens were collected from Bangladeshi cadavers of age ranging from 10 years to 85 years. All the specimens were grouped into three categories Group A (upto 20 years), Group B (21 to 50 years) and Group C (>50 years) according to age. Dissection was performed according to standard autopsy techniques. The weight of the thyroid glands were measured and recorded. The mean weight of the thyroid gland was 6.94 ± 5.20 gm in Group A, 7.91 ± 5.89 gm in Group B and 10.42 ± 6.27 gm in Group C. The mean weight of the thyroid gland in male was 7.0 ± 5.77 gm in Group A, 9.94 ± 7.63 gm in Group B and 11.89 ± 5.73 gm in Group C and in female was 6.88 ± 4.88 gm in Group A, 5.88 ± 2.15 gm in Group B and 9.10 ± 6.74 gm in Group C. Variance analysis shows that there was no significant difference in mean weight between the Age Group A & B, B & C and C & A. There was significant difference of weight of thyroid gland between sex in age Group B but in Group A and Group C were statistically insignificant. The weight of the thyroid gland was found to increases with age. In statistical analysis, differences between age groups were analyzed by using one way ANOVA test. The present study will help to increase the information pool on the weight of thyroid gland of Bangladeshi people.

  19. What lies beneath: sub-articular long bone shape scaling in eutherian mammals and saurischian dinosaurs suggests different locomotor adaptations for gigantism.

    Science.gov (United States)

    Bonnan, Matthew F; Wilhite, D Ray; Masters, Simon L; Yates, Adam M; Gardner, Christine K; Aguiar, Adam

    2013-01-01

    Eutherian mammals and saurischian dinosaurs both evolved lineages of huge terrestrial herbivores. Although significantly more saurischian dinosaurs were giants than eutherians, the long bones of both taxa scale similarly and suggest that locomotion was dynamically similar. However, articular cartilage is thin in eutherian mammals but thick in saurischian dinosaurs, differences that could have contributed to, or limited, how frequently gigantism evolved. Therefore, we tested the hypothesis that sub-articular bone, which supports the articular cartilage, changes shape in different ways between terrestrial mammals and dinosaurs with increasing size. Our sample consisted of giant mammal and reptile taxa (i.e., elephants, rhinos, sauropods) plus erect and non-erect outgroups with thin and thick articular cartilage. Our results show that eutherian mammal sub-articular shape becomes narrow with well-defined surface features as size increases. In contrast, this region in saurischian dinosaurs expands and remains gently convex with increasing size. Similar trends were observed in non-erect outgroup taxa (monotremes, alligators), showing that the trends we report are posture-independent. These differences support our hypothesis that sub-articular shape scales differently between eutherian mammals and saurischian dinosaurs. Our results show that articular cartilage thickness and sub-articular shape are correlated. In mammals, joints become ever more congruent and thinner with increasing size, whereas archosaur joints remained both congruent and thick, especially in sauropods. We suggest that gigantism occurs less frequently in mammals, in part, because joints composed of thin articular cartilage can only become so congruent before stress cannot be effectively alleviated. In contrast, frequent gigantism in saurischian dinosaurs may be explained, in part, by joints with thick articular cartilage that can deform across large areas with increasing load.

  20. What lies beneath: sub-articular long bone shape scaling in eutherian mammals and saurischian dinosaurs suggests different locomotor adaptations for gigantism.

    Directory of Open Access Journals (Sweden)

    Matthew F Bonnan

    Full Text Available Eutherian mammals and saurischian dinosaurs both evolved lineages of huge terrestrial herbivores. Although significantly more saurischian dinosaurs were giants than eutherians, the long bones of both taxa scale similarly and suggest that locomotion was dynamically similar. However, articular cartilage is thin in eutherian mammals but thick in saurischian dinosaurs, differences that could have contributed to, or limited, how frequently gigantism evolved. Therefore, we tested the hypothesis that sub-articular bone, which supports the articular cartilage, changes shape in different ways between terrestrial mammals and dinosaurs with increasing size. Our sample consisted of giant mammal and reptile taxa (i.e., elephants, rhinos, sauropods plus erect and non-erect outgroups with thin and thick articular cartilage. Our results show that eutherian mammal sub-articular shape becomes narrow with well-defined surface features as size increases. In contrast, this region in saurischian dinosaurs expands and remains gently convex with increasing size. Similar trends were observed in non-erect outgroup taxa (monotremes, alligators, showing that the trends we report are posture-independent. These differences support our hypothesis that sub-articular shape scales differently between eutherian mammals and saurischian dinosaurs. Our results show that articular cartilage thickness and sub-articular shape are correlated. In mammals, joints become ever more congruent and thinner with increasing size, whereas archosaur joints remained both congruent and thick, especially in sauropods. We suggest that gigantism occurs less frequently in mammals, in part, because joints composed of thin articular cartilage can only become so congruent before stress cannot be effectively alleviated. In contrast, frequent gigantism in saurischian dinosaurs may be explained, in part, by joints with thick articular cartilage that can deform across large areas with increasing load.

  1. Self-Assembled Monolayers on Gold of β-Cyclodextrin Adsorbates with Different Anchoring Groups

    NARCIS (Netherlands)

    Méndez Ardoy, Alejandro; Steentjes, Tom; Kudernac, Tibor; Huskens, Jurriaan

    2014-01-01

    We designed multivalent β-cyclodextrin-based adsorbates bearing different anchoring groups aiming to yield stable monolayers with improved packing and close contact of the cavity to the gold surface. Toward this end the primary rim of the β-cyclodextrin was decorated with several functional groups,

  2. A standardized approach to qualitative content analysis of focus group discussions from different countries.

    NARCIS (Netherlands)

    Moretti, F.; Vliet, L. van; Bensing, J.; Deledda, G.; Mazzi, M.; Rimondini, M.; Zimmermann, C.; Fletcher, I.

    2011-01-01

    OBJECTIVE: To describe the methodological procedures of a multi-centre focus group research for obtaining content categories also suitable for categorical statistical analyses. METHODS: Inductive content analyses were performed on a subsample of 27 focus groups conducted in three different countries

  3. Doing Anger Differently: Two Controlled Trials of Percussion Group Psychotherapy for Adolescent Reactive Aggression

    Science.gov (United States)

    Currie, Michael; Startup, Mike

    2012-01-01

    This study evaluates efficacy and effectiveness of "Doing Anger Differently" (DAD), a group treatment for reactively aggressive 12-15 year old males. DAD uses percussion exercises to aid treatment. Study 1 compared a ten-week treatment with a waitlist control at pre, post and 6 month (treatment group only) follow-up. Study 2 replicated Study 1,…

  4. A standardized approach to qualitative content analysis of focus group discussions from different countries.

    NARCIS (Netherlands)

    Moretti, F.; Vliet, L. van; Bensing, J.; Deledda, G.; Mazzi, M.; Rimondini, M.; Zimmermann, C.; Fletcher, I.

    2011-01-01

    OBJECTIVE: To describe the methodological procedures of a multi-centre focus group research for obtaining content categories also suitable for categorical statistical analyses. METHODS: Inductive content analyses were performed on a subsample of 27 focus groups conducted in three different countries

  5. Time to Maximal Voluntary Isometric Contraction (MVC) for Five Different Muscle Groups in College Adults.

    Science.gov (United States)

    Morris, A. F.; And Others

    1983-01-01

    College men and women were studied to ascertain the force-time components of a rapid voluntary muscle contraction for five muscle groups. Researchers found that the time required for full contraction differs: (1) in men and women; and (2) among the five muscle groups. (Authors/PP)

  6. On the relative role of different age groups in influenza epidemics

    Directory of Open Access Journals (Sweden)

    Colin J. Worby

    2015-12-01

    While the relative importance of different age groups in propagating influenza outbreaks varies, children aged 5–17 play the leading role during the largest influenza A epidemics. Extra vaccination efforts for this group may contribute to reducing the epidemic's impact in the whole community.

  7. Integration of individual and social information for decision-making in groups of different sizes

    National Research Council Canada - National Science Library

    Seongmin A Park; Sidney Goïame; Jean-Claude Dreher

    2017-01-01

    ... (individual information) with those of others (social information). Here, we investigated the neurocomputational mechanisms of how we adapt our judgments to those made by groups of different sizes, in the context of jury decisions for a criminal...

  8. Group Differences in Test-Taking Behaviour: An Example from a High-Stakes Testing Program

    Science.gov (United States)

    Stenlund, Tova; Eklöf, Hanna; Lyrén, Per-Erik

    2017-01-01

    This study investigated whether different groups of test-takers vary in their reported test-taking behaviour in a high-stakes test situation. A between-group design (N = 1129) was used to examine whether high and low achievers, as well as females and males, differ in their use of test-taking strategies, and in level of reported test anxiety and…

  9. Group Differences in Test-Taking Behaviour: An Example from a High-Stakes Testing Program

    Science.gov (United States)

    Stenlund, Tova; Eklöf, Hanna; Lyrén, Per-Erik

    2017-01-01

    This study investigated whether different groups of test-takers vary in their reported test-taking behaviour in a high-stakes test situation. A between-group design (N = 1129) was used to examine whether high and low achievers, as well as females and males, differ in their use of test-taking strategies, and in level of reported test anxiety and…

  10. Group cohesion in exercise classes: An examination of gender and type of exercise class differences

    Directory of Open Access Journals (Sweden)

    Hülya Aşçı

    2011-10-01

    Full Text Available Group cohesion has been attributed to the higher levels of attendance and performance and lower levels of drop-outs in exercise classes. Cohesion can be affected by different type of exercise classes and gender. Therefore, the main purpose of the study was to compare the group cohesion levels of martial arts participants (aikido, taekwondo, karate, and kendo with aerobic-like participants (aerobics, aero-steps, phys-gym, and high-low aerobics. This causal comparative study also aimed at examining sex differences in group cohesion in exercise classes. There were 140 participants (Mage=28.1 SD= 8.01 and female= 138 male= 2 in aerobic-like classes and 137 participants (Mage= 22.2 SD= 3.8 and female= 48 male= 89 in martial arts classes. Results revealed no sex differences between the groups on the perceptions of cohesion. On the other hand, except for individual attractions to the group-task dimension, participants of martial art classes had higher levels of group cohesion than the participants of aerobic-like classes. Consequently, it was concluded that different types of exercise classes may have different levels of cohesion and those differences were discussed within the context of exercise classes.

  11. Group cohesion in exercise classes: An examination of gender and type of exercise class differences

    Directory of Open Access Journals (Sweden)

    Selçuk Akpınar

    2011-10-01

    Full Text Available Group cohesion has been attributed to the higher levels of attendance and performance and lower levels of drop-outs in exercise classes. Cohesion can be affected by different type of exercise classes and gender. Therefore, the main purpose of the study was to compare the group cohesion levels of martial arts participants (aikido, taekwondo, karate, and kendo with aerobic-like participants (aerobics, aero-steps, phys-gym, and high-low aerobics. This causal comparative study also aimed at examining gender differences in group cohesion in exercise classes. There were 140 participants (Mage=28.1 SD= 8.01 and female= 138 male= 2 in aerobic-like classes and 137 participants (Mage= 22.2 SD= 3.8 and female= 48 male= 89 in martial arts classes. Results revealed no gender differences between the groups on the perceptions of cohesion. On the other hand, except for individual attractions to the group-task dimension, participants of martial art classes had higher levels of group cohesion than the participants of aerobic-like classes. Consequently, it was concluded that different types of exercise classes may have different levels of cohesion and those differences were discussed within the context of exercise classes. 

  12. Focus Groups Reveal Differences in Career Experiences Between Male and Female Geoscientists

    Science.gov (United States)

    Oconnell, S.; Frey, C. D.; Holmes, M.

    2003-12-01

    We conducted twelve telephone focus groups of geoscientists to discover what motivates geoscientists to enter our field and stay in our field. There were separate male and female groups from six different professional categories: administrators, full and associate professors, non-tenure track personnel, assistant professors, post-docs and PhD candidates, Bachelor's and Master's candidates. A total of 96 geoscientists participated. Specifically, respondents were asked what initially brought them into the geosciences. Three dominant themes emerged: the subject matter itself, undergraduate experiences, and relationships. A total of 51 responses to this question related to the subject matter itself. Approximately 61 percent (31) of those responses were given by male focus group participants. Across all focus groups, participants brought up issues such as a general appreciation of the outdoors, weather, rocks, and dinosaurs. Following closely behind the general subject matter is undergraduate events. Fifty-one responses mentioned something about undergraduate experiences such as an introductory class, a laboratory experience, or field experiences. While both female and male participants discussed the role of interpersonal relationships in their decision to become a geoscientist, females were slightly more likely to bring up relevant relationships (26 times for females compared to 21 for males). These relationships varied in both groups from a parent or grandparents influence to camping trips with professors. When respondents were asked whether they had ever considered leaving the geosciences and under what circumstances, there was a striking difference between males and females: males were far less likely to have ever considered leaving. Younger males were more likely to consider leaving than older geoscientists. They feel challenged by the financial constraints of graduate school and the time constraints of academic vs. family life. Many females considered leaving at

  13. Prevalence of self-reported food allergy in different age groups of georgian population.

    Science.gov (United States)

    Lomidze, N; Gotua, M

    2015-04-01

    Epidemiological studies in high income countries suggested that a big proportion of the population in Europe and America report adverse reactions to food. Self-reported prevalence of food allergy varied from 1.2% to 17% for milk, 0.2% to 7% for egg, 0% to 2% for peanuts and fish, 0% to 10% for shellfish, and 3% to 35% for any food. The aim of our study was to report the prevalence of self-reported food allergy in the different age groups of Georgian population and to reveal the most common self-reported food allergens. ISAAC phase III study methodology and questionnaires were used for data collection. Questions about food allergy were added to the survey and involved questions about self-reported food allergy. 6-7 years old 6140 children (response rate-94,5%) and 13-14 years old 5373 adolescents (response rate-86,9%) from two locations of Georgia, Tbilisi and Kutaisi were surveyed. 500 randomly assessed adults from Tbilisi aged 18 years and older were added later (response rate-97,6%). Findings revealed that self-reported food allergy among 6-7 years old age group and 13-14 years old age were almost the same (15,7% and 15,9% correspondingly) and slightly lower in adult population - 13,9%. Study revealed, that hen's egg was the commonest implicated food for 6-7 years age group, hazel nut - for 13-14 years old age group followed by hen's egg. Walnut and hazel nut were most reported foods for adult population. The findings also revealed that food allergy is one of the most important risk factor for symptoms associated with asthma (OR-3,05; 95%CI 2.50-3.74), rhinoconjunctivitis (OR-2,85; 95%CI 2.24-3.64) and eczema (OR-5,42; 95%CI 4.08-7.18) in childhood. The data has provided the first epidemiological information related to food allergy among children and adults in Georgia. Results should serve as baseline information for food allergy screening, diagnosis and treatment. Our findings can also inform the public health officials on the disease burden and may offer some

  14. THE DIFFERENCES IN MORAL, GROUP IDENTITY AND THE PERCON’S VARIABILITY DEPENDING ON THE EDUCATION

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    Irina Aleksandrobna Kolinichenko

    2017-06-01

    Results. The results of the study have revealed the dominance of all specified assessment parameters in the group of test subjects with incomplete higher education: higher level of moral development in all dilemmas (the opposition of life values (compassion and following the law, self-interest – the interests of the city (law, business (benefit and law, personal interests (career and the freedom of another person, except for the dilemma of the opposition between the interests of a majority and a single person. The differences have also been revealed between the two groups of test subjects according to the group identity, group variability, the desirability of the common categories of identity.

  15. Constructing a Measurement Method of Differences in Group Preferences Based on Relative Entropy

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    Shiyu Zhang

    2017-01-01

    Full Text Available In the research and data analysis of the differences involved in group preferences, conventional statistical methods cannot reflect the integrity and preferences of human minds; in particular, it is difficult to exclude humans’ irrational factors. This paper introduces a preference amount model based on relative entropy theory. A related expansion is made based on the characteristics of the questionnaire data, and we also construct the parameters to measure differences in the data distribution of different groups on the whole. In this paper, this parameter is called the center distance, and it effectively reflects the preferences of human minds. Using the survey data of securities market participants as an example, this paper analyzes differences in market participants’ attitudes toward the effectiveness of securities regulation. Based on this method, differences between groups that were overlooked by analysis of variance are found, and certain aspects obscured by general data characteristics are also found.

  16. Comparison of Hemagglutination and Hemolytic Activity of Various Bacterial Clinical Isolates Against Different Human Blood Groups

    Science.gov (United States)

    HRV, Rajkumar; Devaki, Ramakrishna

    2016-01-01

    Among the various pathogenic determinants shown by microorganisms hemagglutination and hemolysin production assume greater significance in terms of laboratory identification. This study evaluated the hemagglutination and hemolytic activity of various bacterial isolates against different blood groups. One hundred and fifty bacterial strains, isolated from clinical specimens like urine, pus, blood, and other body fluids were tested for their hemagglutinating and hemolytic activity against human A, B, AB, and O group red blood cells. Among the 150 isolates 81 were Escherichia coli, 18 were Klebsiella pneumoniae, 19 were Pseudomonas aeruginosa, 10 were Pseudomonas spp, six were Proteus mirabilis, and the rest 16 were Staphylococcus aureus. Nearly 85% of the isolates agglutinated A group cells followed by B and AB group (59.3% and 60.6% respectively). Least number of isolates agglutinated O group cells (38.0%). When the hemolytic activity was tested, out of these 150 isolates 79 (52.6%) hemolyzed A group cells, 61 (40.6%) hemolyzed AB group cells, 46 (30.6%) hemolyzed B group cells, and 57 (38.6%) isolates hemolyzed O group cells. Forty-six percent of the isolates exhibited both hemagglutinating and hemolytic property against A group cells, followed by B and AB group cells (28.6% and 21.3% respectively). Least number of isolates i.e., 32 (21.3%) showed both the properties against O group cells. The isolates showed wide variation in their hemagglutination and hemolytic properties against different combinations of human blood group cells. The study highlights the importance of selection of the type of cells especially when human RBCs are used for studying the hemagglutination and hemolytic activity of bacterial isolates because these two properties are considered as characteristic of pathogenic strains. PMID:27014523

  17. Blood pressure differences by ethnic group among United States children and adolescents.

    Science.gov (United States)

    Rosner, Bernard; Cook, Nancy; Portman, Ron; Daniels, Steve; Falkner, Bonita

    2009-09-01

    Large differences in blood pressure (BP) by ethnic group are apparent among adults. There is uncertainty as to whether similar differences by ethnic group exist among children and, if so, the age of onset. BP measurements were obtained from 58 698 children at 78 556 visits using Pediatric Task Force data, a collection of 11 studies with BP data from children and adolescents age 1 to 17 years. Generalized estimating equation methods were used to identify sex-specific differences in body mass index (BMI)-adjusted rates of BP elevation and prehypertension by ethnic group. Significant BMI-adjusted differences in rates of BP elevation were found between Hispanic boys versus white boys (odds ratio: 1.21; 95% CI: 1.07 to 1.37; P=0.002). No overall significant differences were found between black boys versus white boys (odds ratio: 1.03; 95% CI: 0.95 to 1.12; P=0.49); however, there was significant effect modification (P=0.01) with significant differences found for normal-weight boys (BMI: or =85th percentile; OR black versus white: 0.90; 95% CI: 0.78 to 1.05; P=0.20). No overall ethnic group differences in BMI-adjusted rates of hypertension were found for girls. Ethnic differences in prevalence rates of pediatric BP elevation that are not explained by obesity are present, primarily in boys. Whether these differences are attributable to genetic or environmental factors is unknown.

  18. BLOOD PRESSURE DIFFERENCES BY ETHNIC GROUP AMONG U.S. CHILDREN AND ADOLESCENTS

    Science.gov (United States)

    Rosner, Bernard; Cook, Nancy; Portman, Ron; Daniels, Steve; Falkner, Bonita

    2011-01-01

    Large differences in blood pressure by ethnic group are apparent among adults. There is uncertainty as to whether similar differences by ethnic group exist among children and if so, the age of onset. Blood pressure (BP) measurements were obtained from 58,698 children at 78,556 visits using data from the Pediatric Task Force data, a collection of 11 studies with BP data from children and adolescents age 1–17. Generalized estimating equation methods were used to identify sex-specific differences in body mass index (BMI)-adjusted rates of BP elevation and pre-hypertension by ethnic group. Significant BMI-adjusted differences in rates of BP elevation were found between Hispanic boys vs. Caucasian boys (OR = 1.21, 95% CI = 1.07–1.37, p=0.002). No overall significant differences were found between African-American (AA) boys vs. Caucasian (Cauc) boys (OR = 1.03, 95% CI = 0.95–1.12, p=0.49); however, there was significant effect modification (p = 0.01) with significant differences found for normal weight boys (BMI ethnic group differences in BMI-adjusted rates of hypertension were found for girls. Ethnic differences in prevalence rates of pediatric BP elevation that are not explained by obesity are present, primarily in boys. Whether these differences are due to genetic or environmental factors is unknown. PMID:19652080

  19. Body mass index and percent body fat: a meta analysis among different ethnic groups.

    Science.gov (United States)

    Deurenberg, P; Yap, M; van Staveren, W A

    1998-12-01

    To study the relationship between percent body fat and body mass index (BMI) in different ethnic groups and to evaluate the validity of the BMI cut-off points for obesity. Meta analysis of literature data. Populations of American Blacks, Caucasians, Chinese, Ethiopians, Indonesians, Polynesians and Thais. Mean values of BMI, percent body fat, gender and age were adapted from original papers. The relationship between percent body fat and BMI differs in the ethnic groups studied. For the same level of body fat, age and gender, American Blacks have a 1.3 kg/m2 and Polynesians a 4.5 kg/m2 lower BMI compared to Caucasians. By contrast, in Chinese, Ethiopians, Indonesians and Thais BMIs are 1.9, 4.6, 3.2 and 2.9 kg/m2 lower compared to Caucasians, respectively. Slight differences in the relationship between percent body fat and BMI of American Caucasians and European Caucasians were also found. The differences found in the body fat/BMI relationship in different ethnic groups could be due to differences in energy balance as well as to differences in body build. The results show that the relationship between percent body fat and BMI is different among different ethnic groups. This should have public health implications for the definitions of BMI cut-off points for obesity, which would need to be population-specific.

  20. The applicability of measures of socioeconomic position to different ethnic groups within the UK

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    Lambert Helen

    2009-02-01

    Full Text Available Abstract Background In this paper we seek to tease out differences in socioeconomic position between ethnic groups. There are 3 main reasons why conventional socioeconomic indicators and asset based measures may not be equally applicable to all ethnic groups: 1 Differences in response rate to conventional socioeconomic indicators 2 Cultural and social differences in economic priorities/opportunities 3 Differences in housing quality, assets and debt within socioeconomic strata Methods The sample consisted of White (n = 227, African-Caribbean (n = 213 and Indian and Pakistani (n = 233 adults aged between 18 and 59 years living in Leeds as measured in a stratified population survey. Measures included income, education, employment, car ownership, home ownership, housing quality, household assets, investments, debt, perceived ability to obtain various sums and perceived level of financial support given and received. Results Response rates to education and income questions were similar for the different ethnic groups. Overall response rates for income were much lower than those for education and biased towards wealthier people. There were differences between ethnic groups in economic priorities/opportunities particularly in relation to car ownership, home ownership, investment and debt. Differences in living conditions, household assets and debt between ethnic groups were dependent on differences in education; however differences in car ownership, home ownership, ability to obtain £10 000, and loaning money to family/friends and income from employment/self employment persisted after adjustment for education. Conclusion In the UK, education appears to be an effective variable for measuring variation in SEP across ethnic groups but the ability to account for SEP differences may be improved by the addition of car and home ownership, ability to obtain £10 000, loaning money to family/friends and income from employment/self employment. Further research

  1. Clinical-anthropometric characteristics of COPD outpatients belonging to the different groups and having different severity of airway obstruction

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    Gashynova K.Y.

    2015-06-01

    Full Text Available The aim of the study was to compare the clinical and anthropometric characteristics of patients with COPD, which differ in the degree of airways obstruction and belong to groups A, B, C, D in accordance with GOLD, 2011 classification. A total of 112 ambulatory COPD patients in remission made the study sample. Anthropometric data, body mass index, medical history, dyspnea by mMRC scale, and spirometry was performed for all patients. There was confirmed that outpatients with COPD is a heterogeneous group, in which the majority are those with moderate (48.22 % and severe (30.36 %, airway obstruction. Despite the vast majority of men among outpatients, the percentage of women among patients with mild to moderate obstruction (22.58±5.31 % was significantly higher (p=0.002 as compared with those with severe or very severe limitation of airflow (6.00±3.36 %. Patients with severe and very severe obstruction were of significantly older age (p = 0.024. At the same time, the distribution of patients according to the GOLD, 2011 classification, demonstrate that all groups did not differ on any of the anthropometric indicators, including gender and age (p > 0.050. Distribution of patients by groups with different risk for future exacerbations is not a mirror image of gradation in accordance with the degree of airway obstruction. Every second (50.00±4.43 % of cases patient is included in group C and every tenth (10.20±4.32 % belongs to the group D not due to degree of bronchial obstruction, but due to the number of exa­cerbations in the past year. Therefore, in future studies it is advisable to use both principles of patients’ classification.

  2. Differences in Intracellular Fate of Two Spotted Fever Group Rickettsia in Macrophage-Like Cells

    Science.gov (United States)

    Curto, Pedro; Simões, Isaura; Riley, Sean P.; Martinez, Juan J.

    2016-01-01

    Spotted fever group (SFG) rickettsiae are recognized as important agents of human tick-borne diseases worldwide, such as Mediterranean spotted fever (Rickettsia conorii) and Rocky Mountain spotted fever (Rickettsia rickettsii). Recent studies in several animal models have provided evidence of non-endothelial parasitism by pathogenic SFG Rickettsia species, suggesting that the interaction of rickettsiae with cells other than the endothelium may play an important role in pathogenesis of rickettsial diseases. These studies raise the hypothesis that the role of macrophages in rickettsial pathogenesis may have been underappreciated. Herein, we evaluated the ability of two SFG rickettsial species, R. conorii (a recognized human pathogen) and Rickettsia montanensis (a non-virulent member of SFG) to proliferate in THP-1 macrophage-like cells, or within non-phagocytic cell lines. Our results demonstrate that R. conorii was able to survive and proliferate in both phagocytic and epithelial cells in vitro. In contrast, R. montanensis was able to grow in non-phagocytic cells, but was drastically compromised in the ability to proliferate within both undifferentiated and PMA-differentiated THP-1 cells. Interestingly, association assays revealed that R. montanensis was defective in binding to THP-1-derived macrophages; however, the invasion of the bacteria that are able to adhere did not appear to be affected. We have also demonstrated that R. montanensis which entered into THP-1-derived macrophages were rapidly destroyed and partially co-localized with LAMP-2 and cathepsin D, two markers of lysosomal compartments. In contrast, R. conorii was present as intact bacteria and free in the cytoplasm in both cell types. These findings suggest that a phenotypic difference between a non-pathogenic and a pathogenic SFG member lies in their respective ability to proliferate in macrophage-like cells, and may provide an explanation as to why certain SFG rickettsial species are not associated

  3. Differences in intracellular fate of two spotted fever group Rickettsia in macrophage-like cells

    Directory of Open Access Journals (Sweden)

    Pedro Curto

    2016-07-01

    Full Text Available Spotted fever group (SFG rickettsiae are recognized as important agents of human tick-borne diseases worldwide, such as Mediterranean spotted fever (R. conorii and Rocky Mountain spotted fever (R. rickettsii. Recent studies in several animal models have provided evidence of non-endothelial parasitism by pathogenic SFG Rickettsia species, suggesting that the interaction of rickettsiae with cells other than the endothelium may play an important role in pathogenesis of rickettsial diseases. These studies raise the hypothesis that the role of macrophages in rickettsial pathogenesis may have been underappreciated. Herein, we evaluated the ability of two SFG rickettsial species, R. conorii (a recognized human pathogen and R. montanensis (a non-virulent member of SFG to proliferate in THP-1 macrophage-like cells, or within non-phagocytic cell lines. Our results demonstrate that R. conorii was able to survive and proliferate in both phagocytic and epithelial cells in vitro. In contrast, R. montanensis was able to grow in non-phagocytic cells, but was drastically compromised in the ability to proliferate within both undifferentiated and PMA-differentiated THP-1 cells. Interestingly, association assays revealed that R. montanensis was defective in binding to THP-1-derived macrophages; however, the invasion of the bacteria that are able to adhere did not appear to be affected. We have also demonstrated that R. montanensis which entered into THP-1-derived macrophages were rapidly destroyed and partially co-localized with LAMP-2 and cathepsin D, two markers of lysosomal compartments. In contrast, R. conorii was present as intact bacteria and free in the cytoplasm in both cell types. These findings suggest that a phenotypic difference between a non-pathogenic and a pathogenic SFG member lies in their respective ability to proliferate in macrophage-like cells, and may provide an explanation as to why certain SFG rickettsial species are not associated with

  4. [The assessment of flow velocity in carotid and intracranial arteries in three different age groups].

    Science.gov (United States)

    Niebudek, S

    1998-01-01

    In this report we assess the systolic maximal flow velocity in carotid and intracranial arteries in 191 subjects with no history of cerebral vascular disease in 3 age groups: 20-40 years (1 group), 41-60 years (2 group), and above 60 years (3 group). The subjects were assessed using Sonomed Transcranial Doppler Spectrograph according to generally accepted principles. The purpose of the study was to establish the mean value of maximal flow velocity in each particular artery in three age groups, and to observe the changes in this parameter with age. The results were analyzed using statistical methods and a significant decrease in blood flow, Vmax, was found in all investigated arteries. A mean decrease of 8.02% in flow velocity Vmax was found, when comparing groups 2 and 1, and difference 15.99% comparing 3 and 1.

  5. Structure of TatA paralog, TatE, suggests a structurally homogeneous form of Tat protein translocase that transports folded proteins of differing diameter.

    Science.gov (United States)

    Baglieri, Jacopo; Beck, Daniel; Vasisht, Nishi; Smith, Corinne J; Robinson, Colin

    2012-03-01

    The twin-arginine translocation (Tat) system transports folded proteins across bacterial and plant thylakoid membranes. Most current models for the translocation mechanism propose the coalescence of a substrate-binding TatABC complex with a separate TatA complex. In Escherichia coli, TatA complexes are widely believed to form the translocation pore, and the size variation of TatA has been linked to the transport of differently sized substrates. Here, we show that the TatA paralog TatE can substitute for TatA and support translocation of Tat substrates including AmiA, AmiC, and TorA. However, TatE is found as much smaller, discrete complexes. Gel filtration and blue native electrophoresis suggest sizes between ∼50 and 110 kDa, and single-particle processing of electron micrographs gives size estimates of 70-90 kDa. Three-dimensional models of the two principal TatE complexes show estimated diameters of 6-8 nm and potential clefts or channels of up to 2.5 nm diameter. The ability of TatE to support translocation of the 90-kDa TorA protein suggests alternative translocation models in which single TatA/E complexes do not contribute the bulk of the translocation channel. The homogeneity of both the TatABC and the TatE complexes further suggests that a discrete Tat translocase can translocate a variety of substrates, presumably through the use of a flexible channel. The presence and possible significance of double- or triple-ring TatE forms is discussed.

  6. Students of Different Subjects Have Different Levels of Extrinsic and Intrinsic Motivation to Learn English: Two Different Groups of EFL Students in Japan

    Science.gov (United States)

    Green, Kieran; Fujita, Junichi

    2016-01-01

    Here is documented investigation to assess the motivational drivers of a group of Japanese, first-year, dental-university students taking part in compulsory EFL classes and to compare those motivational drivers with an investigation into the motivational drivers of a group of Japanese IT students. There was a clear difference between extrinsic and…

  7. The Nature-Nurture Controversy Revisited: Divorce and Gender as Factors in Children's Racial Group Differences.

    Science.gov (United States)

    Jenkins, Jeanne E.; Guidubaldi, John

    1997-01-01

    Examined divorce and gender as factors in racial differences in performance of elementary age children on Hahnemann Elementary School Behavior Rating Scale, Wechsler Intelligence Scale for Children-Revised, Wide Range Achievement Test, Vineland Teachers Questionnaire, and an interview. Found more racial group differences within the divorced…

  8. Smoking and Adolescence: Exploring Tobacco Consumption and Related Attitudes in Three Different Adolescent Groups in Switzerland

    Science.gov (United States)

    Bosson, Marlene; Maggiori, Christian; Gygax, Pascal Mark; Gay, Christelle

    2012-01-01

    The present study constitutes an investigation of tobacco consumption, related attitudes and individual differences in smoking or non-smoking behaviors in a sample of adolescents of different ages in the French-speaking part of Switzerland. We investigated three school-age groups (7th-grade, 9th-grade, and the second-year of high school) for…

  9. Overweight and obesity among Dutch workers: Differences between occupational groups and sectors

    NARCIS (Netherlands)

    Proper, K.I.; Hildebrandt, V.H.

    2010-01-01

    Purpose To describe the prevalence of overweight and obesity among different occupational groups and sectors in a representative sample of the Dutch working population, and to test whether these differences still exist after adjustment for socio-demographic variables. Methods Cross-sectional data am

  10. Overweight and obesity among Dutch workers: differences between occupational groups and sectors

    NARCIS (Netherlands)

    Proper, K.I.; Hildebrandt, V.H.

    2009-01-01

    Purpose: To describe the prevalence of overweight and obesity among different occupational groups and sectors in a representative sample of the Dutch working population, and to test whether these differences still exist after adjustment for socio-demographic variables. Methods: Cross-sectional data

  11. The Comparison of Different Age Groups on the Attitudes toward and the Use of ICT

    Science.gov (United States)

    Kubiatko, Milan

    2013-01-01

    Different factors may be influencing the use of information and communication technology (ICT). One of the important factors is age. The society is divided into different groups according to age. A well-known age-based categorization, commonly used especially in the field of economics,, is based on whether people belong to the Millennial…

  12. Understanding Disproportionate Representation in Special Education by Examining Group Differences in Behavior Ratings

    Science.gov (United States)

    Peters, Christina D.; Kranzler, John H.; Algina, James; Smith, Stephen W.; Daunic, Ann P.

    2014-01-01

    The aim of the current study was to examine mean-group differences on behavior rating scales and variables that may predict such differences. Sixty-five teachers completed the Clinical Assessment of Behavior-Teacher Form (CAB-T) for a sample of 982 students. Four outcome variables from the CAB-T were assessed. Hierarchical linear modeling was used…

  13. The use and risk of portable electronic devices while cycling among different age groups

    NARCIS (Netherlands)

    Goldenbeld, C.; Houtenbos, M.; Ehlers, E.; De Waard, D.

    Introduction: In the Netherlands, a survey was set up to monitor the extent of the use of portable, electronic devices while cycling amongst different age groups of cyclists and to estimate the possible consequences for safety. Method: The main research questions concerned age differences in the

  14. Understanding Disproportionate Representation in Special Education by Examining Group Differences in Behavior Ratings

    Science.gov (United States)

    Peters, Christina D.; Kranzler, John H.; Algina, James; Smith, Stephen W.; Daunic, Ann P.

    2014-01-01

    The aim of the current study was to examine mean-group differences on behavior rating scales and variables that may predict such differences. Sixty-five teachers completed the Clinical Assessment of Behavior-Teacher Form (CAB-T) for a sample of 982 students. Four outcome variables from the CAB-T were assessed. Hierarchical linear modeling was used…

  15. Sex differences in early-life programming of the hypothalamic-pituitary-adrenal axis in humans suggest increased vulnerability in females: a systematic review.

    Science.gov (United States)

    Carpenter, T; Grecian, S M; Reynolds, R M

    2017-04-01

    Fetal glucocorticoid overexposure is a key mechanism linking early development with later-life disease. In humans, low birth weight associates with increased fasting cortisol, hypothalamic-pituitary-adrenal (HPA) axis reactivity, and with cardiovascular risk and cognitive decline. As there are sex differences in these adult diseases, we hypothesized that there may be sex differences in programming of the HPA axis in response to prenatal stressors. We conducted a systematic review following Meta-Analysis of Observational Studies in Epidemiology and Preferred Reporting Items for Systematic Reviews and Meta-Analysis. We searched Embase, MEDLINE and Web of Science from inception to 31 October 2016. We included studies related to sex differences, prenatal exposures and HPA axis. We excluded studies investigating specific disease states. The 23 included studies investigated the consequences of low birth weight, preterm birth and maternal stressors of asthma, psychosocial stress and glucocorticoid medications on HPA axis outcomes of placental glucocorticoid biology and offspring HPA axis function in early life and later life. Female offspring exposed to stressors had increased HPA axis reactivity compared with males. Furthermore, the female placenta increased its permeability to maternal glucocorticoids following maternal stress with changes in the expression of 11β-hydroxysteroid dehydrogenase enzymes in response to maternal glucocorticoid exposure or asthma. Among males there was some evidence of altered diurnal cortisol secretion. We conclude that although there is some evidence of male vulnerability leading to altered diurnal cortisol secretion, the female HPA axis is more vulnerable to programming, particularly in terms of its reactivity; this suggests a mechanism underlying sex differences in later-life diseases.

  16. 87Sr/86Sr Ratios in Carbonate From the Red Lake and Steep Rock Groups in Canada Suggest Rb-enriched Continental Crust was Influencing Seawater Chemistry Prior to 3.0 Ga

    Science.gov (United States)

    Satkoski, A.; Fralick, P. W.; Beard, B. L.; Johnson, C.

    2015-12-01

    Previous work has suggested that prior to 2.5 Ga, Sr isotope compositions of seawater were essentially mantle buffered and the effects of continental weathering on seawater chemistry were negligible. To test this, we collected Sr isotope data from 2.93 and 2.80 Ga carbonates that are part of the Red Lake and Steep Rock groups (Canada), respectively. To better understand carbonate formation and any post-depositional alteration, Sr isotopes are considered with O isotopes and REEs, as well as Rb and Sr contents, including correction for decay of 87Rb. All samples have Y/Ho ratios higher than chondrite and have positive La anomalies, which, combined with low Rb contents suggests that clastic contamination is negligible. Samples we consider near pristine have δ18O (VSMOW) values >20‰. Samples with the highest Y/Ho ratios and largest La anomalies from Red Lake and Steep Rock have initial 87Sr/86Sr ratios of 0.7018-0.7020. This Sr isotope composition is significantly more radiogenic than contemporaneous mantle (0.7011-0.7012), especially at a time when the isotopic difference between the crust and mantle was much less than today. This implies that radiogenic continental crust was emergent and shed detritus into the world's oceans prior to 3.0 Ga, in contrast with proposals for submerged continental crust, but in line with new estimates that continental crust at 3.0 Ga was 60-70% of current volume. We contend that this large amount of crust combined with enhanced Archean weathering could account for the radiogenic Sr isotope compositions we report here, and suggests a significant impact from continental weathering on ocean chemistry during the Archean.

  17. Genetic and environmental contributions to population group differences on the Raven's Progressive Matrices estimated from twins reared together and apart.

    Science.gov (United States)

    Rushton, J Philippe; Bons, Trudy Ann; Vernon, Philip A; Cvorović, Jelena

    2007-07-22

    We carried out two studies to test the hypothesis that genetic and environmental influences explain population group differences in general mental ability just as they do individual differences within a group. We estimated the heritability and environmentality of scores on the diagrammatic puzzles of the Raven's Coloured and/or Standard Progressive Matrices (CPM/SPM) from two independent twin samples and correlated these estimates with group differences on the same items. In Study 1, 199 pairs of 5- to 7-year-old monozygotic (MZ) and dizygotic (DZ) twins reared together provided estimates of heritability and environmentality for 36 puzzles from the CPM. These estimates correlated with the differences between the twins and 94 Serbian Roma (both rs=0.32; Ns=36; psadult MZ and DZ twins reared apart provided estimates of heritability and environmentality for 58 puzzles from the SPM. These estimates correlated with the differences among 11 diverse samples including (i) the reared-apart twins, (ii) another sample of Serbian Roma, and (iii) East Asian, White, South Asian, Coloured and Black high school and university students in South Africa. In 55 comparisons, group differences were more pronounced on the more heritable and on the more environmental items (mean rs=0.40 and 0.47, respectively; Ns=58; ps<0.05). After controlling for measurement reliability and variance in item pass rates, the heritabilities still correlated with the group differences, although the environmentalities did not. Puzzles found relatively difficult (or easy) by the twins were those found relatively difficult (or easy) by the others (mean r=0.87). These results suggest that population group differences are part of the normal variation expected within a universal human cognition.

  18. Estimating the contribution of genetic variants to difference in incidence of disease between population groups.

    Science.gov (United States)

    Moonesinghe, Ramal; Ioannidis, John P A; Flanders, W Dana; Yang, Quanhe; Truman, Benedict I; Khoury, Muin J

    2012-08-01

    Genome-wide association studies have identified multiple genetic susceptibility variants to several complex human diseases. However, risk-genotype frequency at loci showing robust associations might differ substantially among different populations. In this paper, we present methods to assess the contribution of genetic variants to the difference in the incidence of disease between different population groups for different scenarios. We derive expressions for the contribution of a single genetic variant, multiple genetic variants, and the contribution of the joint effect of a genetic variant and an environmental factor to the difference in the incidence of disease. The contribution of genetic variants to the difference in incidence increases with increasing difference in risk-genotype frequency, but declines with increasing difference in incidence between the two populations. The contribution of genetic variants also increases with increasing relative risk and the contribution of joint effect of genetic and environmental factors increases with increasing relative risk of the gene-environmental interaction. The contribution of genetic variants to the difference in incidence between two populations can be expressed as a function of the population attributable risks of the genetic variants in the two populations. The contribution of a group of genetic variants to the disparity in incidence of disease could change considerably by adding one more genetic variant to the group. Any estimate of genetic contribution to the disparity in incidence of disease between two populations at this stage seems to be an elusive goal.

  19. Glioma cell line proliferation controlled by different chemical functional groups in vitro

    Institute of Scientific and Technical Information of China (English)

    Su-Ju XU; Fu-Zhai CUI; Xiao-Long YU; Xiang-Dong KONG

    2013-01-01

    Glioma cell line C6 cultured on silicon surfaces modified by different chemical functional groups, including mercapto (-SH), carboxyl (-COOH), amino (-NH2), hydroxyl (-OH) and methyl (-CH3) groups, was studied here to investigate the influence of surface chemistry on the cell proliferation, adhesion and apoptosis. AFM confirmed the similar characteristic of different functional groups occupation. The adhering C6 exhibited morphological changes in response to different chemical functional groups. The C6 adhered to -COOH, -NH2, -OH and -CH3 surfaces and flattened morphology, while those on -SH surface exhibited the smallest contact area with mostly rounded morphology, which led to the death of cancer cells. The results of MTT assay showed that the -COOH and -NH2 groups promoted ceil proliferation, while the -SH significantly inhibited the proliferation. Compared with other chemical functional groups, the -SH group exhibited its unique effect on the fate of cancer cells, which might provide means for the design of biomaterials to prevent and treat glioma.

  20. Age Group Differences in Perceived Age Discrimination: Associations With Self-Perceptions of Aging.

    Science.gov (United States)

    Giasson, Hannah L; Queen, Tara L; Larkina, Marina; Smith, Jacqui

    2017-08-01

    From midlife onwards, age stereotypes increasingly underlie social judgments and contribute to age-based discrimination. Whereas many studies compare differences between young and older adults in reports of age discrimination or sensitivity to age stereotypes, few consider age group differences among adults over 50. We form subgroups corresponding to social age group membership (early midlife, late midlife, young old, oldest old) and examine differences in reported experiences of everyday age discrimination and associations with self-perceptions of aging. Using cross-sectional and longitudinal data from the Health and Retirement Study (HRS: N = 15,071; M Age = 68, range 50-101), multivariate logistic regression was used to examine experiences of everyday discrimination attributed to age, and associations between age discrimination and self-perceptions of aging, in four age groups: early midlife, late midlife, young old, oldest old. People in the early midlife group (aged 50-59) reported more experiences of unfair treatment than the older age groups but were less likely to attribute their experiences to age discrimination. After controlling for covariates, individuals in all age groups who perceived their own aging positively were less likely to report experiences of age discrimination. The magnitude of this effect, however, was greatest in the early midlife group. Findings support proposals that midlife is a pivotal life period when individuals adjust to life events and social role transitions. Future longitudinal studies will provide further insight into whether positive self-perceptions of aging are especially important in this phase of the life course.

  1. [Effect of obesity on pulmonary function in asthmatic children of different age groups].

    Science.gov (United States)

    Xu, Xiao-Wen; Huang, Ying; Wang, Jian; Zhang, Xue-Li; Liang, Fan-Mei; Luo, Rong

    2017-05-01

    To study the effect of obesity on pulmonary function in newly diagnosed asthmatic children of different age groups. Two hundred and ninety-four children with newly diagnosed asthma were classified into preschool-age (obese, overweight, and normal-weight subgroups based on their body mass index (BMI). All the children underwent pulmonary function tests, including large airway function tests [forced vital capacity (FVC%) and forced expiratory volume in one second (FEV1%)] and small airway function tests [maximal expiratory flow at 25% of vital capacity (MEF25%), maximal expiratory flow at 50% of vital capacity (MEF50%), and maximal expiratory flow at 75% of vital capacity (MEF75%)]. The school-age group showed lower FEV1%, MEF25%, and MEF50% than the preschool-age group (Pchildren in the school-age group had lower FEV1%, MEF25%, and MEF50% compared with their counterparts in the preschool-age group (Pchildren in the school-age group showed lower FVC% and MEF50% than those in the preschool-age group. However, all the pulmonary function parameters showed no significant differences between the obese children in the preschool-age and school-age groups. In the preschool-age group, FVC%, FEV1%, and MEF75% of the obese children were lower than those of the normal-weight children. In the school-age group, only FVC% and FEV1% showed differences between the obese and normal-weight children (Pobesity on the pulmonary function varies with age in children with asthma, and the effect is more obvious in those of preschool age.

  2. Clinical and immunological characteristics of hemorrhagic fever with renal syndrome in women of different age groups

    Directory of Open Access Journals (Sweden)

    Kutdusova A.M.

    2012-09-01

    Full Text Available Objective: To evaluate the clinical and immunological features of the hemorrhagic fever with renal syndrome in women of different age groups. Materials and methods: Clinical and laboratory characteristics of hemorrhagic fever with renal syndrome in 148 women aged 17 to 65 years old have been investigated. Patients have been divided into two groups: group I included 101 patients with normal menstrual rhythm, group II included 47 female patients with menopause. In 57 women (36 from group I, 21 — from group II the content of CD3+, CD4+, CD8+, CD16+, CD19+ — sub-populations of peripheral blood lymphocytes has been determined. Results: In compared groups significant differences in structure and frequency of complications of the disease have been revealed. Unidirectional tendency to increase significantly reduced absolute rates of investigated lymphocyte subpopulations in dynamics of the disease has been identified. It also has been stated that by the time of early convalescence in case of severe form of HFRS the indices did not reach the standard level. In an older group of women deeper damage and long-term recovery of immune system have been marked. Conclusion: According to the results of clinical and immunological studies the research work has revealed that in young women the response of the immune system to HFRS has developed faster and stronger than that in patients during the menopause period.

  3. Individualisation of Migration from the East? Comparison of Different Socio-Demographic Groups and their Migration Intentions

    Directory of Open Access Journals (Sweden)

    Maarja Saar

    2016-12-01

    Full Text Available Recent studies on Eastern European migration argue that moving for self-development reasons is becoming increasingly common among this group. Furthermore, it is suggested that migration from the East is becoming individualised and less dependent on social surroundings. Nevertheless, most such results rely on interviews conducted among certain social groups, such as the young and highly skilled. Hence, the comparison between different social groups and their motivations is rarely provided and, therefore, the claims about increased individualisation might be premature. This article uses the Estonian Household Module Survey, including responses from 620 Estonians intending to migrate, to evaluate if migration flows are indeed becoming more individualised and less dependent on social surroundings. Using cluster analysis, three different groups — self-development, economic and life quality migrants — are formed, which are then tested using regression analysis to check for the influence of socio-demographic variables. The article concludes that socio-demographic variables such as gender, age, ethnicity, family status and socio-economic status are still relevant for migration intentions. Indeed, a new group of Eastern European migrants, mainly oriented towards self-development, is emerging; however, it is small and consists mostly of young, Estonian-speaking females. The results complicate the notions of free mobility and liquid migration from Eastern Europe and illustrate that there is a need to pay attention to the increasing group differences in these societies

  4. Mitochondrial carbonic anhydrase CA VB: differences in tissue distribution and pattern of evolution from those of CA VA suggest distinct physiological roles.

    Science.gov (United States)

    Shah, G N; Hewett-Emmett, D; Grubb, J H; Migas, M C; Fleming, R E; Waheed, A; Sly, W S

    2000-02-15

    A cDNA for a second mouse mitochondrial carbonic anhydrase (CA) called CA VB was identified by homology to the previously characterized murine CA V, now called CA VA. The full-length cDNA encodes a 317-aa precursor that contains a 33-aa classical mitochondrial leader sequence. Comparison of products expressed from cDNAs for murine CA VB and CA VA in COS cells revealed that both expressed active CAs that localized in mitochondria, and showed comparable activities in crude extracts and in mitochondria isolated from transfected COS cells. Northern blot analyses of total RNAs from mouse tissues and Western blot analyses of mouse tissue homogenates showed differences in tissue-specific expression between CA VB and CA VA. CA VB was readily detected in most tissues, while CA VA expression was limited to liver, skeletal muscle, and kidney. The human orthologue of murine CA VB was recently reported also. Comparison of the CA domain sequence of human CA VB with that reported here shows that the CA domains of CA VB are much more highly conserved between mouse and human (95% identity) than the CA domains of mouse and human CA VAs (78% identity). Analysis of phylogenetic relationships between these and other available human and mouse CA isozyme sequences revealed that mammalian CA VB evolved much more slowly than CA VA, accepting amino acid substitutions at least 4.5 times more slowly since each evolved from its respective human-mouse ancestral gene around 90 million years ago. Both the differences in tissue distribution and the much greater evolutionary constraints on CA VB sequences suggest that CA VB and CA VA have evolved to assume different physiological roles.

  5. Differences Between Colon Cancer Primaries and Metastases Using a Molecular Assay for Tumor Radiation Sensitivity Suggest Implications for Potential Oligometastatic SBRT Patient Selection

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, Kamran A. [Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida (United States); Fulp, William J.; Berglund, Anders E. [Department of Biostatistics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida (United States); Hoffe, Sarah E.; Dilling, Thomas J. [Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida (United States); Eschrich, Steven A. [Department of Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida (United States); Shridhar, Ravi [Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida (United States); Torres-Roca, Javier F., E-mail: javier.torresroca@moffitt.org [Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida (United States)

    2015-07-15

    Purpose: We previously developed a multigene expression model of tumor radiation sensitivity index (RSI) with clinical validation in multiple independent cohorts (breast, rectal, esophageal, and head and neck patients). The purpose of this study was to assess differences between RSI scores in primary colon cancer and metastases. Methods and Materials: Patients were identified from our institutional review board–approved prospective observational protocol. A total of 704 metastatic and 1362 primary lesions were obtained from a de-identified metadata pool. RSI was calculated using the previously published rank-based algorithm. An independent cohort of 29 lung or liver colon metastases treated with 60 Gy in 5 fractions stereotactic body radiation therapy (SBRT) was used for validation. Results: The most common sites of metastases included liver (n=374; 53%), lung (n=116; 17%), and lymph nodes (n=40; 6%). Sixty percent of metastatic tumors, compared with 54% of primaries, were in the RSI radiation-resistant peak, suggesting metastatic tumors may be slightly more radiation resistant than primaries (P=.01). In contrast, when we analyzed metastases based on anatomical site, we uncovered large differences in RSI. The median RSIs for metastases in descending order of radiation resistance were ovary (0.48), abdomen (0.47), liver (0.43), brain (0.42), lung (0.32), and lymph nodes (0.31) (P<.0001). These findings were confirmed when the analysis was restricted to lesions from the same patient (n=139). In our independent cohort of treated lung and liver metastases, lung metastases had an improved local control rate compared to that in patients with liver metastases (2-year local control rate of 100% vs 73.0%, respectively; P=.026). Conclusions: Assessment of radiation sensitivity between primary and metastatic tissues of colon cancer histology revealed significant differences based on anatomical location of metastases. These initial results warrant validation in a larger

  6. Photo-physical and interactional behavior of two members of group B vitamins in different solvent media

    Science.gov (United States)

    Zakerhamidi, M. S.; Zare Haghighi, L.; Seyed Ahmadian, S. M.

    2017-09-01

    In this paper, absorption and fluorescence spectra of vitamin B12 (cyanocobalamin) and vitamin B6 (pyridoxine) were recorded in solvents with different polarity, at room temperature. These vitamins' photo-physical behavior depends strongly on the solvent's nature along with different attached groups in their structures. In order to investigate the solvent-solute interactions and environmental effect on spectral variations, linear solvation energy relationships concept, suggested by Kamlet and Taft was used. Solvatochromic method was also used for measuring the ground and excited state dipole moments of these vitamins. According to our experimental results, dipole moment of these groups of vitamins in excited state is larger than ground state. Furthermore, obtained photo-physical and interactional properties of used vitamins can give important information on how this group of vitamins behaves in biological systems.

  7. Dynamics of hormonal status in women of different age groups in hemorrhagic fever with renal syndrome

    Directory of Open Access Journals (Sweden)

    Murzabaeva R.Т.

    2012-06-01

    Full Text Available Objective: To study the hormonal parameters in women of different age groups in hemorrhagic fever with renal syndrome. Materials and methods: We have studied the content of cortisol, thyrotropic hormone (TTH, triiodothyro-nine (T3, free thyroxin (FT4, luteinizing hormone (LH, follicle-stimulating hormone (FSH, testosterone, estradiol, progesterone, prolactin in blood serum of 62 women with moderate (33 and severe (29 HFRS forms age (17-62. They were divided into 2 groups: the first group (33 patients women with the normal menstrual cycle, the second group (29 women consisted of patients in climacteric period. Results: TTH secretion increase, T3 and FT4 — decrease with their normalization to the recovery period were registered in the thyroid system of the compared groups. Blood cortisol level was high during the illness. Gonadotropic hypophysis function study demonstrated that LH and blood prolactin concentrations were increased since oliguria period; FSH was authentic reduced. The indices of these hormones were restored to the normal level by the reconvalescence period. LH and FSH contents were authentic higher in women of the second group in comparison with the first group. The hyperprolactinemia was observed in both women groups during the whole period of disease. The increased progesterone and testosterone concentrations have been manifested in blood serum. The estradiol concentration had different direction tendencies. Conclusion: Thus, the complex study of hypophysic- thyreoid and gonadotropic hormone state of adrenal system and the sexual hormone levels in women of different age groups in HFRS revealed the hormone status indces changes due to the period and severity of the disease, connected with the virus action, intoxication, the general inflammation reactions and their age.

  8. Cultural and age differences of three groups of Taiwanese young children's creativity and drawing.

    Science.gov (United States)

    Wei, Mei-Hue; Dzeng, Annie

    2013-06-01

    This study investigated the cultural and age effects on children's overall creativity and drawing. 1,055 children ages 6 to 8 from three groups--urban and rural Taiwanese children and Taiwanese children of immigrant mothers, all in public schools--were given a creativity test, a people-drawing test, and a free-drawing test. The results showed that the older Taiwanese children scored higher than the young Taiwanese children on people-drawing and free-drawing, but not overall creativity. Drawing and creativity scores increased in accordance with age. In the six-year-old group, a group difference was found only on the scale of people-drawing. Urban Taiwanese children in the eight-year-old group scored higher than the other two groups of children on creativity and free-drawing. Results are discussed in terms of educational opportunities.

  9. Predictability and Reliability of Different Anterio-Posterior Skeletal Discrepancy Indicators in Different Age Groups - A Cephalometric Study

    Science.gov (United States)

    Tiwari, Rana; Gupta, Abhishek; Joshi, Rishi; Tiwari, Anil; Sen, Priyank

    2016-01-01

    Introduction The lateral cephalometric skeletal discrepancy indicators play a major role in diagnosing and preparing a case for orthognathic surgeries and the dentofacial corrections. Aim The study was aimed to check the reliability and the predictability of different anterio-posterior skeletal discrepancy indicators in different age groups and to derive the most reliable indicator for the orthodontic diagnosis. Materials and Methods A cross-sectional study was conducted on a sample of 100 subjects including 29 adolescent (15 males and 14 females) and 71 adult (41 males and 30 females) subjects with the mean age of 19.05 ± 5.78 years. All the subjects had Angle’s Class I molar relationship. The lateral cephalograms of the sample were taken under the standard setting and hand tracing of the cephalometric radiographs using a sharp 4H pencil were made on acetate tracing paper. The anterio-posterior cephalometric indicators like β-angle, Wits appraisal (mm), Sella- Nasion plane to Point A and Point B distance (SN-AB mm) and Maxillo-Mandibular plane angle bisector to Point A and Point B distance (MM-AB mm) were measured. Intra-examiner reliability of tracings was evaluated using Intra Class Correlation (ICC) test. Mann Whitney U-test was applied for comparison of parameters between different malocclusion groups. Concurrent validity of various parameters was calculated using Cohen’s kappa. A p-value <0.05 was considered statistically significant. Results The comparison of intra-examiner reliability of tracings in Angle’s Class I adolescent group showed, MM-AB to have an almost perfect agreement followed by Wits. Intra-examiner reliability of tracings in Angle’s Class I adult group showed moderate agreement for Wits and MM-AB showed almost perfect agreement and all the parameters showed statistically significant ICC. Comparison of parameters between adolescent and adult, Angle’s Class I malocclusion group showed significant difference between adolescent and

  10. ANALYSIS OF RAILWAY USER TRAVEL BEHAVIOUR PATTERNS OF DIFFERENT AGE GROUPS

    Directory of Open Access Journals (Sweden)

    Takamasa AKIYAMA

    2009-01-01

    Full Text Available In recent years, there have been requirments for a transport environment that will foster the development of safe, comfortable townships. The study of urban activities amid an aging society and effective use of public transport modes in addressing environmental problems have become particularly important issues. This study analyzes travel behaviour patterns of varying age groups using urban railways in order to examine the relationship between urban public transport use and urban activities. specifically, it analyzes the composition of urban activity and travel behaviour patterns among urban railway users in the Keihanshin (Kyoto-Osaka-Kobe metropolitan area. This paper looks at urban activities within aging societies and identifies the differences in travel behaviour of railway users by separating them into young, middle aged and senior citizen age groups. Analysis makes particular use of the Railway station Database, which is a compilation of existing studies into attributes of railway stations and their surroundings, and results of person trip surveys. Rail use behaviour characteristics have been sorted by age group because mobility via urban railway systems is varied by age group. As a result, differences in railway usage patterns (travel objectives, distance and time, and number of transfers, etc. have been identified and so too have differences in urban activity patterns related to free activities (shopping, recreation. Furthermore, the study developed a travel behaviour pattern estimation model which is capable of categorizing specific transport behaviour patterns and estimating rail users and transport behaviour patterns from the relationship with areas surrounding railway stations to ensure future mobility by public transport for older age groups. The results make it possible to put forward proposals for urban rail services that will facilitate urban activities for the different age groups. Eventually, it will be possible to understand

  11. Typing of feline calicivirus isolates from different clinical groups by virus neutralisation tests.

    Science.gov (United States)

    Dawson, S; McArdle, F; Bennett, M; Carter, M; Milton, I P; Turner, P; Meanger, J; Gaskell, R M

    1993-07-03

    One hundred and thirteen isolates of feline calicivirus originating from seven different clinical groups were typed by virus neutralisation tests using eight different cat antisera. The clinical groups comprised 'healthy' cats, cases of acute oral/respiratory disease, chronic stomatitis, acute febrile lameness syndrome, vaccine reactions (clinical disease seen within 21 days of vaccination) and vaccine breakdowns (clinical disease seen more than 21 days after but within one year of vaccination). Isolates from the vaccine reaction cases were grouped into those associated with acute oral/respiratory disease alone and those associated with the lameness syndrome, and the latter group was further subdivided according to the vaccine used. Two groups appeared significantly different from others with some of the antisera. Thus the lameness vaccine reaction isolates associated with vaccine B were significantly different from the isolates from all the other clinical groups, including other lameness isolates, with a number of the antisera. In addition, the chronic stomatitis isolates were significantly different from those from the 'healthy' and the acute oral/respiratory disease groups with one or two of the antisera. Eighty-five to 88 per cent of the isolates were neutralised by antisera raised against F9 or F9-like vaccine strains at a dilution of 1 in 2. Twenty antibody units of such antisera neutralised 42 to 80 per cent of the isolates. A bivalent antiserum raised against a vaccine F9 strain and field strain LS015 neutralised 96 per cent of the isolates at a dilution of 1 in 2, and 20 antibody units neutralised 68 per cent of isolates. Antisera to field strain F65 neutralised all the remaining isolates at a dilution of 1 in 2 and 44 per cent of the remaining isolates at a dilution of 20 antibody units. Therefore, strains LS015 and F65 may be of use in the production of a polyvalent feline calicivirus vaccine, together with the widely used strain F9.

  12. Parameter identification and synchronization for uncertain network group with different structures

    Science.gov (United States)

    Li, Chengren; Lü, Ling; Sun, Ying; Wang, Ying; Wang, Wenjun; Sun, Ao

    2016-09-01

    We design a novel synchronization technique to research the synchronization of network group constituted of uncertain networks with different structures. Based on Lyapunov theorem, the selection principles of the control inputs and the parameter identification laws of the networks are determined, and synchronization conditions of the network group are obtained. Some numerical simulations are provided to verify the correctness and effectiveness of the synchronization technique. We find that the network number, the number of network nodes and network connections indeed will not affect the stability of synchronization of network group.

  13. [Symptomatic and asymptomatic infections of Demodex spp. in eye lashes of patients of different age groups].

    Science.gov (United States)

    Kuźna-Grygiel, Wanda; Kosik-Bogacka, Danuta; Czepita, Damian; Sambor, Izabella

    2004-01-01

    Demodex folliculorum and Demodex brevis were looked for on eyelashes sampled from 481 people, aged 3 through 96. The persons studied were divided into 9 age groups. Magnitude of the infection symptoms was assessed based on macroscopic changes of eye-lid edges and on interviews with patients. An increase of the prevalence of infection and intensification of the symptoms were observed to coincide with the age increase of the persons studied. No significant differences were demonstrated between the infection frequencies of women and men. Symptoms of ocular demodecosis were more frequent only in women of group III (aged 21-30) and group V (41-50) (p < 0.05).

  14. Prevalence of primary headache disorders diagnosed according to ICHD-3 beta in three different social groups

    DEFF Research Database (Denmark)

    Lebedeva, Elena R; Kobzeva, Natalia R; Gilev, Denis

    2016-01-01

    .5% in blood donors. Age-adjusted prevalence of tension-type headache (TTH) among females was almost the same in students and blood donors (68.8% and 66.7%) but female workers had a lower prevalence of TTH (57%). Age-adjusted prevalence of TTH among males did not differ significantly between students and blood...... prevalence was high and differed markedly among the three social groups. It is important that headache epidemiology also focus on socially defined groups in order to target future preventive efforts.......BACKGROUND: The aim of our study was to estimate the one-year prevalence of primary headache disorders in three different social groups using the third edition beta of the International Classification of Headache Disorders (ICHD-3 beta). MATERIAL AND METHODS: The study population included a total...

  15. Catalytical Activities of Reconstructed Hemoglobin with Different Central Ions in Prosthetic Group

    Institute of Scientific and Technical Information of China (English)

    LIU Jian-yu; SUN Bao-wei; LI Yuan-zong; CHANG Wen-bao

    2003-01-01

    Hemoglobin(Hb) was de-prosthetized, which was then reconstructed with the prosthetic groups with different central metal ions including Fe(Ⅲ), Co(Ⅱ) and Mn(Ⅱ). The spectral properties along with the catalase and peroxidase activities of the reconstructed hemoglobin were compared with those of Hb and prosthetic groups with different ions. When the central ion is iron, the reconstituted Hb(rHb) has the highest catalase and peroxidase activities. Maybe it is the reason that iron is chosen as the central ion in the prosthetic groups of natural hemoproteins. Different from peroxidase activity, the catalase activity of hemin cannot be enhanced by the microenvironment of apoHb. This result shows that the structure of apoHb is more similar to that of apoHRP than that of apocatalase.

  16. Dominant negative phenotype of Bacillus thuringiensis Cry1Ab, Cry11Aa and Cry4Ba mutants suggest hetero-oligomer formation among different Cry toxins.

    Directory of Open Access Journals (Sweden)

    Daniela Carmona

    Full Text Available BACKGROUND: Bacillus thuringiensis Cry toxins are used worldwide in the control of different insect pests important in agriculture or in human health. The Cry proteins are pore-forming toxins that affect the midgut cell of target insects. It was shown that non-toxic Cry1Ab helix α-4 mutants had a dominant negative (DN phenotype inhibiting the toxicity of wildtype Cry1Ab when used in equimolar or sub-stoichiometric ratios (1∶1, 0.5∶1, mutant∶wt indicating that oligomer formation is a key step in toxicity of Cry toxins. METHODOLOGY/PRINCIPAL FINDINGS: The DN Cry1Ab-D136N/T143D mutant that is able to block toxicity of Cry1Ab toxin, was used to analyze its capacity to block the activity against Manduca sexta larvae of other Cry1 toxins, such as Cry1Aa, Cry1Ac, Cry1Ca, Cry1Da, Cry1Ea and Cry1Fa. Cry1Ab-DN mutant inhibited toxicity of Cry1Aa, Cry1Ac and Cry1Fa. In addition, we isolated mutants in helix α-4 of Cry4Ba and Cry11Aa, and demonstrate that Cry4Ba-E159K and Cry11Aa-V142D are inactive and completely block the toxicity against Aedes aegypti of both wildtype toxins, when used at sub-stoichiometric ratios, confirming a DN phenotype. As controls we analyzed Cry1Ab-R99A or Cry11Aa-E97A mutants that are located in helix α-3 and are affected in toxin oligomerization. These mutants do not show a DN phenotype but were able to block toxicity when used in 10∶1 or 100∶1 ratios (mutant∶wt probably by competition of binding with toxin receptors. CONCLUSIONS/SIGNIFICANCE: We show that DN phenotype can be observed among different Cry toxins suggesting that may interact in vivo forming hetero-oligomers. The DN phenotype cannot be observed in mutants affected in oligomerization, suggesting that this step is important to inhibit toxicity of other toxins.

  17. Profiling of Junior College Football Players and Differences between Position Groups

    Directory of Open Access Journals (Sweden)

    Robert G. Lockie

    2016-08-01

    Full Text Available This study profiled junior college football players. Sixty-two subjects completed vertical jump (VJ; height and peak power, standing broad jump (SBJ, 36.58 m sprint, pro-agility shuttle, three-cone drill, and maximal-repetition bench press and front squat. The sample included 2 quarterbacks (QB, 7 running backs (RB, 13 wide receivers (WR, 1 tight end (TE, 18 defensive backs (DB, 8 linebackers (LB, and 13 offensive and defensive linemen (LM. To investigate positional differences, subjects were split into skill (SK; WR, DB, big skill (BSK; QB, RB, TE, LB, and LM groups. A one-way ANOVA determined between-group differences. LM were taller and heavier than SK and BSK players. The SK and BSK groups were faster than LM in the 0–36.58 m sprint, pro-agility shuttle, and three-cone drill (p ≤ 0.009. The SK group had greater VJ height and SBJ distance; LM generated greater VJ peak power (p ≤ 0.022. There were no between-group differences in the strength endurance tests. Compared to Division I data, junior college players were smaller, slower, and performed worse in jump tests. Positional differences in junior college football are typical to that of established research. Junior college players should attempt to increase body mass, and improve speed and lower-body power.

  18. Identifying target groups for environmentally sustainable transport: assessment of different segmentation approaches

    DEFF Research Database (Denmark)

    Haustein, Sonja; Hunecke, Marcel

    2013-01-01

    Recently, the use of attitude-based market segmentation to promote environmentally sustainable transport has significantly increased. The segmentation of the population into meaningful groups sharing similar attitudes and preferences provides valuable information about how green measures should...... be designed and promoted in order to attract different user groups. This review highlights advances in the understanding of mode choice from a psychological perspective, taking into account behavioural theories of car use and car-use reduction. In this contribution, attitudinal, sociodemographic, geographical...... and behavioural segmentations are compared regarding marketing criteria. Although none of the different approaches can claim absolute superiority, attitudinal approaches show advantages in providing startingpoints for interventions to reduce car use....

  19. Cognitive-behavioral group therapy for girls victims of sexual violence in Brazil: Are there differences in effectiveness when applied by different groups of psychologists?: effectiveness of group therapy for girls victims of sexual violence

    Directory of Open Access Journals (Sweden)

    Luisa Fernanda Habigzang

    Full Text Available The effectiveness of a cognitive-behavioral group therapy model for the treatment of girls victims of sexual violence (SV was investigated when applied by different groups of practitioners: researchers/psychologists who developed it (G1 and psychologists from the public social care network trained by the first group (G2. A quasi-experimental study was carried out, in which the group therapy model was applied by the two groups. A total of 103 girls victims of sexual violence (SV, aged between seven and 16 years (M=11.76 years, SD=2.02 years were included, with 49 attended by G1, and 54 by G2. The results indicated a significant reduction in the symptoms of depression, anxiety, stress, and PTSD. The comparison between the results obtained by the two groups of practitioners in the application of the model indicated no significant differences in the rates of improvement of the participants. These results indicate the effectiveness of the cognitive-behavioral group therapy model evaluated and the possibility of it being used as a care strategy by psychology practitioners working in public services.

  20. Persistent organohalogen contaminants in plasma from groups of humans with different occupations in Bangladesh.

    Science.gov (United States)

    Zamir, R; Athanasiadou, M; Nahar, N; Mamun, M I R; Mosihuzzaman, M; Bergman, A

    2009-01-01

    The present study is aimed to assess persistent organic halogenated pollutants in humans living in Bangladesh. The results are compared to other similar studies in the region and globally. Human blood plasma were collected from groups of men and women with different occupations, i.e. being students, garment industry workers, employees at the Power Development Board (PDB), all groups in Dhaka, fishermen and fishermen wife's from Dhaka and another group from Barisal district. The plasma was analysed for hexachlorobenzene (HCB), the hexachlorocyclohexane isomers, alpha-HCH, beta-HCH, gamma-HCH and delta-HCH, the DDT group of chemicals, chlordane compounds, trans-chlordane, cis-chlordane, oxychlordane, trans-nonachlor, trans-heptachlorepoxide, methoxychlor and mirex. The most abundant contaminant, in all groups studied, p,p'-DDE is dominating, with p,p'-DDT/Sigma DDT ratios indicating recent and ongoing DDT exposure. Among the other pesticides analysed beta-HCH is the most abundant indicating the use of technical HCH products instead of Lindane (gamma-HCH). While the Sigma DDT is present in the low ppm range the beta-HCH is detected in up to approx. 400 ppb, lipid basis. The beta-HCH is most abundant in the groups of students. In contrast to the pesticides analysed very low concentrations of polychlorinated biphenyls (PCB) are present in all study groups, with e.g. CB-153 in the range of 5-30 ng g(-1) fat. The concentrations of the DDT group of chemical differ significantly between fishermen and fishermen's wives living and working in the Dhaka area versus those living and working in Barisal. Also, fishermen and their wives had significantly different concentrations of DDT compared to garment industry workers.

  1. Analysis of postural control and muscular performance in young and elderly women in different age groups

    Directory of Open Access Journals (Sweden)

    Matheus M. Gomes

    2015-02-01

    Full Text Available BACKGROUND: muscle strength and power are two factors affecting balance. The impact of muscle strength and power on postural control has not been fully explored among different age strata over sixty. OBJECTIVES: the aim of the present study was to assess the muscle strength and power of elderly women in different age groups and determine their correlation with postural control. METHOD: eighty women were divided into four groups: the young 18-30 age group (n=20; the 60-64 age group (n=20; the 65-69 age group (n=20; and the 70-74 age group (n=20. The participants underwent maximum strength (one repetition maximum or 1-RM and muscle power tests to assess the knee extensor and flexor muscles at 40%, 70%, and 90% 1-RM intensity. The time required by participants to recover their balance after disturbing their base of support was also assessed. RESULTS: the elderly women in the 60-64, 65-69, and 70-74 age groups exhibited similar muscle strength, power, and postural control (p>0.05; however, these values were lower than those of the young group (p<0.05 as expected. There was a correlation between muscle strength and power and the postural control performance (p<0.05. CONCLUSION: despite the age difference, elderly women aged 60 to 74 years exhibited similar abilities to generate strength and power with their lower limbs, and this ability could be one factor that explains the similar postural control shown by these women.

  2. Physical-psychiatric comorbidity: patterns and explanations for ethnic group differences.

    Science.gov (United States)

    Erving, Christy L

    2017-02-07

    This paper examines ethnic differences in the co-occurrence of physical and psychiatric health problems (physical-psychiatric comorbidity) for women and men. The following ethnic groups are included: Non-Latino Whites, African Americans, Caribbean Blacks, Spanish Caribbean Blacks, Mexicans, Cubans, Puerto Ricans, Other Latinos, Chinese, Filipinos, Vietnamese, and Other Asian Americans. In addition, the study assesses the extent to which social factors (socioeconomic status, stress exposure, social support) account for ethnic differences in physical-psychiatric comorbidity (PPC). This study uses data from the Collaborative Psychiatric Epidemiology Surveys (CPES) (N = 12,787). Weighted prevalence rates of physical-psychiatric comorbidity (PPC) - the co-occurrence of physical and psychiatric health problems - are included to examine ethnic group differences among women and men. Multinomial logistic regression analysis was used to determine group differences in PPC before and after adjusting for social factors. Puerto Rican men have significantly higher risk of PPC in comparison to Non-Latino White men. Among women, Blacks and Cubans were more likely than Non-Latino Whites to experience PPC as opposed to 'Psychiatric Only' health problems. Social factors account for the Puerto Rican/Non-Latino White difference in comorbid health among men, but have little explanatory power for understanding ethnic differences in comorbidity among women. These findings have implications for medical care and can guide intervention programs in targeting a specific constellation of co-occurring physical and psychiatric health problems for diverse ethnic groups in the United States. As comorbidity rates increase, it is crucial to identify the myriad factors that give rise to ethnic group differences therein.

  3. Electrical conductivity of old oceanic mantle in the northwestern Pacific I: 1-D profiles suggesting differences in thermal structure not predictable from a plate cooling model

    Science.gov (United States)

    Baba, Kiyoshi; Tada, Noriko; Matsuno, Tetsuo; Liang, Pengfei; Li, Ruibai; Zhang, Luolei; Shimizu, Hisayoshi; Abe, Natsue; Hirano, Naoto; Ichiki, Masahiro; Utada, Hisashi

    2017-08-01

    Seafloor magnetotelluric (MT) experiments were recently conducted in two areas of the northwestern Pacific to investigate the nature of the old oceanic upper mantle. The areas are far from any tectonic activity, and "normal" mantle structure is therefore expected. The data were carefully analyzed to reduce the effects of coastlines and seafloor topographic changes, which are significant boundaries in electrical conductivity and thus distort seafloor MT data. An isotropic, one-dimensional electrical conductivity profile was estimated for each area. The profiles were compared with those obtained from two previous study areas in the northwestern Pacific. Between the four profiles, significant differences were observed in the thickness of the resistive layer beyond expectations based on cooling of homogeneous oceanic lithosphere over time. This surprising feature is now further clarified from what was suggested in a previous study. To explain the observed spatial variation, dynamic processes must be introduced, such as influence of the plume associated with the formation of the Shatsky Rise, or spatially non-uniform, small-scale convection in the asthenosphere. There is significant room of further investigation to determine a reasonable and comprehensive interpretation of the lithosphere-asthenosphere system beneath the northwestern Pacific. The present results demonstrate that electrical conductivity provides key information for such investigation.[Figure not available: see fulltext.

  4. Child mental health differences amongst ethnic groups in Britain: a systematic review

    Directory of Open Access Journals (Sweden)

    Leon David A

    2008-07-01

    Full Text Available Abstract Background Inter-ethnic differences have been reported for many mental health outcomes in the UK, but no systematic review on child mental health has been published. The aim of this review is to compare the population-based prevalence of child mental disorders between ethnic groups in Britain, and relate these findings to ethnic differences in mental health service use. Methods A systematic search of bibliographic databases for population-based and clinic-based studies of children aged 0–19, including all ethnic groups and the main child mental disorders. We synthesised findings by comparing each minority group to the White British study sample. Results 31 population-based and 18 clinic-based studies met the inclusion criteria. Children in the main minority groups have similar or better mental health than White British children for common disorders, but may have higher rates for some less common conditions. The causes of these differences are unclear. There may be unmet need for services among Pakistani and Bangladeshi children. Conclusion Inter-ethnic differences exist but are largely unexplained. Future studies should address the challenges of cross-cultural psychiatry and investigate reasons for inter-ethnic differences.

  5. Interpreting the clinical importance of group differences in chronic pain clinical trials: IMMPACT recommendations.

    Science.gov (United States)

    Dworkin, Robert H; Turk, Dennis C; McDermott, Michael P; Peirce-Sandner, Sarah; Burke, Laurie B; Cowan, Penney; Farrar, John T; Hertz, Sharon; Raja, Srinivasa N; Rappaport, Bob A; Rauschkolb, Christine; Sampaio, Cristina

    2009-12-01

    An essential component of the interpretation of results of randomized clinical trials of treatments for chronic pain involves the determination of their clinical importance or meaningfulness. This involves two distinct processes--interpreting the clinical importance of individual patient improvements and the clinical importance of group differences--which are frequently misunderstood. In this article, we first describe the essential differences between the interpretation of the clinical importance of patient improvements and of group differences. We then discuss the factors to consider when evaluating the clinical importance of group differences, which include the results of responder analyses of the primary outcome measure, the treatment effect size compared to available therapies, analyses of secondary efficacy endpoints, the safety and tolerability of treatment, the rapidity of onset and durability of the treatment benefit, convenience, cost, limitations of existing treatments, and other factors. The clinical importance of individual patient improvements can be determined by assessing what patients themselves consider meaningful improvement using well-described methods. In contrast, the clinical meaningfulness of group differences must be determined by a multi-factorial evaluation of the benefits and risks of the treatment and of other available treatments for the condition in light of the primary goals of therapy. Such determinations must be conducted on a case-by-case basis, and are ideally informed by patients and their significant others, clinicians, researchers, statisticians, and representatives of society at large.

  6. Driver style and driver skill – Clustering sub-groups of drivers differing in their potential danger in traffic

    DEFF Research Database (Denmark)

    Martinussen, Laila Marianne; Møller, Mette; Prato, Carlo Giacomo

    based on a combined use of the DBQ and the DSI. Moreover, the joint use of the two instruments was applied to identify sub-groups of drivers that differ in their potential danger in traffic (as measured by frequency of aberrant driving behaviors and level of driving skills), as well as to test whether...... the sub-groups of drivers differed in characteristics such as age, gender, annual mileage and accident involvement. 3908 drivers aged 18–84 participated in the survey. The results suggested that the drivers are consistent in their reporting of driving ability, as the self-reported driving skill level...... mirrored the self-reported frequency of aberrant driving behaviors. K-means cluster analysis revealed four distinct clusters that differed in the frequency of aberrant driving behavior and driving skills, as well as individual characteristics and driving related factors such as annual mileage, accident...

  7. Differences in Intracellular Fate of Two Spotted Fever Group Rickettsia in Macrophage-Like Cells

    OpenAIRE

    Pedro Curto; Isaura Simoes; Riley, Sean P; Juan Jose Martinez

    2016-01-01

    Spotted fever group (SFG) rickettsiae are recognized as important agents of human tick-borne diseases worldwide, such as Mediterranean spotted fever (Rickettsia conorii) and Rocky Mountain spotted fever (Rickettsia rickettsii). Recent studies in several animal models have provided evidence of non-endothelial parasitism by pathogenic SFG Rickettsia species, suggesting that the interaction of rickettsiae with cells other than the endothelium may play an important role in pathogenesis of rickett...

  8. Relationships between Gross Motor Abilities and Problematic Behaviors of Handicapped Children in Different Age Groups.

    Science.gov (United States)

    Uesugi, Masayuki; Araki, Tomoko; Fujii, Shun; Itotani, Keisuke; Otani, Yoshitaka; Seiichi, Takemasa

    2014-12-01

    [Purpose] In this study, we examined problematic behaviors of independent-walking and non-independent-walking handicapped children in the infant, school child and adolescent development phases, using the Japanese version of the Aberrant Behavior Checklist (ABC-J) to determine if such behaviors relate to their gross motor abilities. [Subjects and Methods] The subjects were 86 handicapped children who were receiving physical therapy. The subjects were classified into three groups by age. Using the Gross Motor Function Classification System (GMFCS), each group was further divided into an independent-walking group and non-independent-walking group. Thirteen physical therapists and 8 occupational therapists, who were treating the subject children, rated the subjects using the ABC-J. [Results] Significant differences were observed between the independent-walking and the non-independent-walking groups in the stereotypy and lethargy scores of infants. [Conclusion] For schoolchildren and adolescents, no significant differences were observed between the independent-walking and the non-independent-walking groups in their problematic behavior scores.

  9. Difference between the attitudes towards minority groups among parents and their children

    OpenAIRE

    Mićević Jelena

    2005-01-01

    The aim of this research is to establish if there are differences between discrimination attitudes of parents and their children towards various marginal groups (the Chinese, Roma, the rich, the poor, persons of different sex, disabled persons). 849 persons were examined in this research: 310 of children and 539 of parents. The questionnaire of identical form for parents and their children was used to examine these discrimination attitudes. The questionnaire contains the open-type questions a...

  10. A network-level explanation for the differences in HIV prevalence in South Africa's racial groups.

    Science.gov (United States)

    Kenyon, Chris; Dlamini, Sipho; Boulle, Andrew; White, Richard G; Badri, Motasim

    2009-09-01

    Analyses of individual-level risk factors have not been able to adequately explain why HIV has spread so extensively in southern Africa and why this has occurred especially within certain racial or ethnic groups. Using data from a longitudinal study of a representative sample of adolescents aged 14-22 living in Cape Town, South Africa, this article presents evidence of how differences in individual-level risk factors as well as sexual network structures between different racial or ethnic groups may help explain the differential spread of HIV in South Africa. Particular emphasis is placed on how levels of partner concurrency, respondent concurrency, mutual concurrency, serial concurrency and numbers of sexual partners and an average early age of sexual debut combine in different ways in the different racial or ethnic groups to create networks of sexual partnerships that differ in the density of their interconnections and hence potential for HIV spread. These network-level differences offer a potential explanation for the observed generalised HIV epidemic seen among the population of black South Africans.

  11. Electrochemiluminescent Detection of Hydrogen Peroxide via Some Luminol Imide Derivatives with Different Substituent Groups

    Directory of Open Access Journals (Sweden)

    Tifeng Jiao

    2013-01-01

    Full Text Available Some luminol imide derivatives with different substituent groups have been designed and synthesized. Their electrochemiluminescence properties have been measured with a view to developing new biosensors. The ECL response to hydrogen peroxide in the presence of these luminescent derivatives has been investigated taking into account crucial factors such as the applied potential value, injection volume of hydrogen peroxide, and the substituent groups in molecular structures. The experimental data demonstrated that the substituent groups in these imide derivatives can have a profound effect upon the ECL abilities of these studied compounds. The present research work affords new and useful exploration for the design and development of new soft matter for ECL biosensors with luminol functional groups.

  12. The Effects of Social Misdirection on Magic Tricks: How Deceived and Undeceived Groups Differ

    Directory of Open Access Journals (Sweden)

    Ryo Tachibana

    2014-05-01

    Full Text Available Characteristics of perception and cognition in our daily lives can be elucidated through studying misdirection, a technique used by magicians to manipulate attention. Recent findings on the effects of social misdirection induced by joint attention have been disputed, and differences between deceived (failed to detect the magic trick and undeceived (detected the magic trick groups remain unclear. To examine how social misdirection affects deceived and undeceived groups, we showed participants movie clips of the “cups & balls,” a classic magic trick, and measured participants' eye positions (i.e. where participants looked while viewing the clips using an eye tracker. We found that the undeceived group looked less at the magician's face than the deceived group. These results indicate that deceived individuals have difficulty trying not to allocate attention to the face. We conclude that social misdirection captures attention, influencing the emergence of deception.

  13. Growth, bone maturation, and biochemical changes in Brazilian children from two different socioeconomic groups.

    Science.gov (United States)

    Linhares, E D; Round, J M; Jones, D A

    1986-10-01

    A study of blood biochemistry related to skeletal growth in 900 Brazilian children aged 7 to 17 yr is reported. Two groups were studied, a privileged and underprivileged sample. Anthropometry and measures of bone maturation in the control group were comparable with American and British standards. Underprivileged children showed growth impairment and delay in bone maturation. No signs of rickets were found in either group. Plasma calcium, magnesium, vitamin D, and total protein did not differ in the two groups of Brazilian children. Plasma alkaline phosphatase and inorganic phosphorus were abnormal in the underprivileged children. Alkaline-phosphatase activity and phosphorus levels did not fall towards adult levels after the predicted age of the adolescent spurt for underprivileged children. Menarche was delayed in the underprivileged girls.

  14. Ethnic group differences in cardiometabolic disease risk factors independent of body mass index among American youth.

    Science.gov (United States)

    Messiah, Sarah E; Arheart, Kristopher L; Lopez-Mitnik, Gabriela; Lipshultz, Steven E; Miller, Tracie L

    2013-03-01

    The purpose of this analysis was to identify any ethnic group differences in the prevalence of cardiometabolic disease risk factors independent of BMI in United States youth. Data on 3,510 boys and girls aged 8-11 years from the 1999-2008 National Health and Nutrition Examination Surveys were analyzed to determine the prevalence of 1 or ≥3 cardiometabolic disease risk factors: abnormal waist circumference and systolic (SBP) and diastolic blood pressure (DBP), increased concentrations of fasting triglyceride, and decreased concentrations of high-density lipoprotein (HDL) cholesterol before and after adjusting for BMI. Abnormal waist circumference and HDL-cholesterol significantly differed by ethnic group before and after adjusting for BMI (P ethnic group disparities not related to BMI alone, even in children as young as 8-11 years. Programs to prevent and treat eventual cardiometabolic disease in children could be tailored for specific ethnic backgrounds as a result. Copyright © 2013 The Obesity Society.

  15. Different stories of group work: Exploring problem solving in engineering education

    Directory of Open Access Journals (Sweden)

    Maria Berge

    2012-06-01

    Full Text Available This article aims to further the understanding of group work in higher education, primarily in science.This is done through an empirical investigation of problem solving in small groups. Position theory isused as an analytic tool for describing the complex and dynamic processes of group work, focusing simultaneously on the physics content and the student community and how they constitute each other. We analysed four video-recorded sessions with students from two Master’s programs, Engineering Physics and Bioengineering, respectively. The students addressed two introductory mechanics problems.The analysis resulted in a characterisation in terms of seven ‘storylines’ of two different kinds. These are argued to reflect different aspects of engineering student communities, where one kind of storylines captures ways of approaching the problems and the other kind exemplifies boundary work involved in the constitution of communities.

  16. Grouping Normal Type Ia Supernovae by UV to Optical Color Differences

    CERN Document Server

    Milne, Peter A; Roming, Peter W A; Bufano, Filomena; Gehrels, Neil

    2013-01-01

    Observations of many SNe Ia with the UVOT instrument on the Swift satellite has revealed that there exists order to the differences in the UV-OPT colors of normal SNe. We examine UV-OPT color curves for 25 SNe Ia, dividing them into 4 groups, finding that ~1/3 of these SNe Ia have bluer UV-OPT colors than the larger group, with these "NUV-blue" SNe Ia 0.4 mag bluer than the "NUV-red" SNe Ia in u-v. Another group of events feature colors similar to NUV-red SNe Ia in the u-v to uvw1-v colors, but similar to the NUV-blue SNe Ia in the uvm2-v color. We name these events "MUV-blue". The last group initially has colors similar to NUV-red SNe Ia, but with color curves that feature more modest changes than the larger NUV-red group. These "irregular" events are comprised of all the NUV-red events with the broadest optical peaks, which leads us to consider this minor group a subset of the NUV-red group. When so separated and the accounting is made for the rapid time evolution of the UV-OPT colors, we find that the scat...

  17. Job Search and the Theory of Planned Behavior: Minority-Majority Group Differences in The Netherlands

    Science.gov (United States)

    van Hooft, Edwin A. J.; Born, Marise Ph.; Taris, Toon W.; van der Flier, Henk

    2004-01-01

    The labor market in many Western countries increasingly diversifies. However, little is known about job search behavior of ''non-traditional'' applicants such as ethnic minorities. This study investigated minority-majority group differences in the predictors of job search behavior, using the theory of planned behavior (Ajzen, 1985). Data were…

  18. The Knowledge-Based Reasoning of Physical Education Teachers: A Comparison between Groups with Different Expertise

    Science.gov (United States)

    Reuker, Sabine

    2017-01-01

    The study addresses professional vision, including the abilities of selective attention and knowledge-based reasoning. This article focuses on the latter ability. Groups with different sport-specific and pedagogical expertise (n = 60) were compared according to their observation and interpretation of sport activities in a four-field design. The…

  19. Differences Between Human Figure Drawings of Child Molesters and Control Groups.

    Science.gov (United States)

    Johnston, Frances A.; Johnston, Shawn A.

    1986-01-01

    Attempted to identify differences between human figure drawings of adult and juvenile child molesters and adult and juvenile control groups, based on ratings obtained for psychodiagnostic signs. Results revealed, for the molesters, factors of overall quality with a component of gender identity confusion, figure-size only, fingers only, and hidden…

  20. [Features of arterial blood pressure in elderly persons of different ethnic groups in Yakutsk].

    Science.gov (United States)

    Nikitin, Iu P; Tatarinova, O V; Neustroeva, V N; Shcherbakova, L V; Sidorov, A S

    2013-01-01

    The differences in arterial blood pressure in the sample of population in the age of 60 and older of different ethnic groups in Yakutsk, as well as its connection with the other cardiovascular diseases risk factors have been analyzed. It was shown that the average values of systolic and diastolic blood pressure in subsample of the Yakuts appeared to be lower than in Caucasoid gerontic persons. The average values of systolic arterial blood pressure both in the Yakuts and in the Caucasoids were detected higher than normal values in all age-dependent subgroups. The average values of diastolic blood pressure in both ethnic groups were within the limits of high normal level. From 60 to 90 years and older the decrease in systolic and diastolic arterial blood pressure was detected; it was more marked in Caucasoid gerontic persons. The average values of pulse pressure in the Yakuts and in the Caucasoids appeared to be higher than the existing standard and didn't have any differences in ethnic groups. In both ethnical subsamples, pulse pressure values increase was observed in persons of 60-89 years old and its decrease after 90. Persons with overweight, obesity, central (abdominal) obesity, dyslypoproteidemias irrespective of belonging to ethnical group were characterized as having higher levels of arterial blood pressure. Statistically significant differences in the levels of arterial blood pressure in the Yakuts and in the Caucasoids depending on hyperglycemia, smoking, the presence of burdened anamnesis, educational level, marital status was not detected.

  1. Radio vs. Television: Their Cognitive Impact on Children of Different Socioeconomic and Ethnic Groups.

    Science.gov (United States)

    Greenfield, Patricia; Beagles-Roos, Jessica

    1988-01-01

    Reports on two studies which compared the impact of radio and television on children from different social classes and ethnic groups. Found that radio was more stimulating than television to the imagination (especially among white children) and that television led to greater overall recall of information. (ARH)

  2. Diagnostic Group Differences in Parent and Teacher Ratings on the BRIEF and Conners' Scales

    Science.gov (United States)

    Sullivan, Jeremy R.; Riccio, Cynthia A.

    2007-01-01

    Objective: Behavioral rating scales are common instruments used in evaluations of ADHD and executive function. It is important to explore how different diagnostic groups perform on these measures, as this information can be used to provide criterion-related validity evidence for the measures. Method: Data from 92 children and adolescents were used…

  3. Correlates of sedentary time in different age groups: results from a large cross sectional Dutch survey

    NARCIS (Netherlands)

    Bernaards, C.; Hildebrandt, V.H.; Hendriksen, I.J.

    2016-01-01

    Background. Evidence shows that prolonged sitting is associated with an increased risk of mortality, independent of physical activity (PA). The aim of the study was to identify correlates of sedentary time (ST) in different age groups and day types (i.e. school-/work day versus non-school-/non-work

  4. Self-Compassion among College Counseling Center Clients: An Examination of Clinical Norms and Group Differences

    Science.gov (United States)

    Lockard, Allison J.; Hayes, Jeffrey A.; Neff, Kristin; Locke, Benjamin D.

    2014-01-01

    There has been growing interest in the mental health benefits of self-compassion. This study was designed to establish norms on the Self-Compassion Scale-Short Form, a popular measure of self-compassion for individuals seeking counseling, and to examine group differences in self-compassion based on gender, race/ethnicity, sexual orientation,…

  5. Psychosocial Concerns of Sexual Minority Youth: Complexity and Caution in Group Differences

    Science.gov (United States)

    Poteat, V. Paul; Aragon, Steven R.; Espelage, Dorothy L.; Koenig, Brian W.

    2009-01-01

    This investigation tested a large adolescent sample (n = 14,439) for significant group differences on psychosocial concerns on the basis of intersecting identities of sexual orientation (lesbian, gay, bisexual, questioning/less certain, heterosexual), race (Whites, racial minorities), and gender (boys, girls). A significant 2-way interaction…

  6. Job search and the theory of planned behavior: Minority – majority group differences in The Netherlands

    NARCIS (Netherlands)

    E.A.J. van Hooft (Edwin); M.Ph. Born (Marise); T.W. Taris (Toon); H. van der Flier (Henk)

    2003-01-01

    textabstractThe labor market in many Western countries increasingly diversifies. However, little is known about job search behavior of 'non-traditional' applicants such as ethnic minorities. This study investigated minority – majority group differences in the predictors of job search behavior, using

  7. Cultural Orientations in the United States: (Re)Examining Differences among Ethnic Groups.

    Science.gov (United States)

    Coon, Heather M.; Kemmelmeier, Markus

    2001-01-01

    Investigated differences in individualism and collectivism between the U.S.'s four largest ethnic groups (African Americans, Asian Americans, Hispanic Americans, and European Americans). Surveys of Michigan college students indicated that Asian Americans and African Americans but not Hispanic Americans scored higher in collectivism that did…

  8. Does the EDI Measure School Readiness in the Same Way across Different Groups of Children?

    Science.gov (United States)

    Guhn, Martin; Gadermann, Anne; Zumbo, Bruno D.

    2007-01-01

    The present study investigates whether the Early Development Instrument (Offord & Janus, 1999) measures school readiness similarly across different groups of children. We employ ordinal logistic regression to investigate differential item functioning, a method of examining measurement bias. For 40,000 children, our analysis compares groups…

  9. Job search and the theory of planned behavior: Minority – majority group differences in The Netherlands

    NARCIS (Netherlands)

    E.A.J. van Hooft (Edwin); M.Ph. Born (Marise); T.W. Taris (Toon); H. van der Flier (Henk)

    2003-01-01

    textabstractThe labor market in many Western countries increasingly diversifies. However, little is known about job search behavior of 'non-traditional' applicants such as ethnic minorities. This study investigated minority – majority group differences in the predictors of job search behavior, using

  10. Group differences in the aesthetic evaluation of nature development plans : A multilevel approach

    NARCIS (Netherlands)

    van den Berg, AE; Vlek, CAJ; Coeterier, JF

    1998-01-01

    The study presented here addresses theoretical, methodological and practical aspects of the issue of group differences in the aesthetic evaluation of natural landscapes. Beauty ratings of an agrarian landscape and five computer simulations of nature development plans in this landscape were collected

  11. Learning Mathematics with Technology: The Influence of Virtual Manipulatives on Different Achievement Groups

    Science.gov (United States)

    Moyer-Packenham, Patricia; Suh, Jennifer

    2012-01-01

    This study examined the influence of virtual manipulatives on different achievement groups during a teaching experiment in four fifth-grade classrooms. During a two-week unit focusing on two rational number concepts (fraction equivalence and fraction addition with unlike denominators) one low achieving, two average achieving, and one high…

  12. Defining dimensions of distinctiveness : Group variability makes a difference to differentiation

    NARCIS (Netherlands)

    Jetten, J; Spears, R; Manstead, ASR

    1998-01-01

    We tested the prediction, derived from an integration of social identity and self-categorization principles, that the relation between in-group distinctiveness and positive differentiation is curvilinear. Moderate distinctiveness is argued to provide the critical combination of intergroup difference

  13. The effect of interventions on Twitter in four target groups using different measures of influence

    NARCIS (Netherlands)

    Maanen, P.P. van; Wijn, R.; Boertjes, E.

    2014-01-01

    In this paper, the influence of interventions on Twitter users is studied. We define influence in (a) number of participants, (b) size of the audience, (c) amount of activity, and (d) reach. Influence is studied for four different target groups: (a) politicians, (b) journalists, (c) employees and (d

  14. The effect of interventions on Twitter in four target groups using different measures of influence

    NARCIS (Netherlands)

    Maanen, P.P. van; Wijn, R.; Boertjes, E.

    2014-01-01

    In this paper, the influence of interventions on Twitter users is studied. We define influence in (a) number of participants, (b) size of the audience, (c) amount of activity, and (d) reach. Influence is studied for four different target groups: (a) politicians, (b) journalists, (c) employees and (d

  15. Influence of controlled and uncontrolled interventions on Twitter in different target groups

    NARCIS (Netherlands)

    Maanen, P.P. van; Aarts, O.; Boertjes, E.; Wijn, R.

    2013-01-01

    In this paper the influence of interventions on Twitter users is studied. We define influence in a) number of participants, b) size of the audience, c) amount of activity, and d) reach. Influence is studied for four different target groups: a) politicians, b) journalists, c) employees and d) the gen

  16. Using Different Methods to Access the Difficult Task of Delimiting Species in a Complex Neotropical Hyperdiverse Group

    Science.gov (United States)

    Costa-Silva, Guilherme J.; Rodriguez, Mónica S.; Roxo, Fábio F.; Foresti, Fausto; Oliveira, Claudio

    2015-01-01

    The genus Rineloricaria is a Neotropical freshwater fish group with a long and problematic taxonomic history, attributed to the large number of species and the pronounced similarity among them. In the present work, taxonomic information and different molecular approaches were used to identify species boundaries and characterize independent evolutionary units. We analyzed 228 samples assembled in 53 distinct morphospecies. A general mixed yule-coalescent (GMYC) analysis indicated the existence of 70 entities, while BOLD system analyses showed the existence of 56 distinct BINs. When we used a new proposed integrative taxonomy approach, mixing the results obtained by each analysis, we identified 73 OTUs. We suggest that Rineloricaria probably has some complexity in the known species and several species not formally described yet. Our data suggested that other hyperdiverse fish groups with wide distributions can be further split into many new evolutionary taxonomic units. PMID:26332320

  17. Consumption of Cisatracurium in different age groups, using a closed loop computer controlled system.

    Science.gov (United States)

    Joomye, Shehzaad; Yan, Donglai; Wang, Haiyun; Zhou, Guoqiang; Wang, Guolin

    2014-01-01

    We devised this study to quantify the effect of age on the consumption of cisatracurium under general anaesthesia, using a computer controlled closed loop infusion system. We further investigated this effect on, sufentanil and propofol consumption. 74 patients of physical status I and II, requiring general anaesthesia for elective abdominal surgery, were assigned to three groups. Patients in group 1 were aged from 20 to 45, group 2 were from 46 to 64, and group 3 above 65 years old. General Anesthesia was maintained with propofol and muscle paralysis was maintained using a closed-loop computer controlled infusion of cisatracurium. For analgesia, intermittent bolus of sufentanil 10 μg was given. Cisatracurium consumption in group 1, 2 and 3 were 1.8 ± 0.3, 1.6 ± 0.4 and 1.3 ± 0.4 μg/kg/min respectively. There was significant difference of cisatracurium consumption between group 1 and 3 (P = 0.002), and the consumption of cisatracurium in group 3 was less as compared with group 2 (P = 0.04). The average recovery index of patients in group 1, 2 and 3 were 8.8 ± 2.6, 11.5 ± 2.9 and 12.7 ± 2.5 minutes respectively. There were difference between group 1 and 2 (P = 0.02). As compared with group 1, the recovery index was still longer in group 3 (P = 0.001). Patients in group 1, 2 and 3 consumed an average sufentanil 0.4 ± 0.1, 0.4 ± 0.1 and 0.3 ± 0.1 μg/kg/hr, respectively. There were statistical significant between group 1 and 3 (P < 0.0001), and the same trend was found between group 2 and 3 (P = 0.03). The Consumption of propofol in group 1, 2 and 3 were 5.1 ± 0.4, 4.3 ± 0.6 and 3.1 ± 0.5 mg/kg/hr. The difference in the propofol consumption was found statistically significant when comparing between any two groups. We concluded that the sensitivity of anesthetic agents increased with age. Less medication was required to achieve a desirable effect in older patients specially those

  18. Dynamics of telomere length in different age groups in a Latvian population.

    Science.gov (United States)

    Zole, Egija; Pliss, Liana; Ranka, Renate; Krumina, Astrida; Baumanis, Viesturs

    2013-12-01

    The shortening of telomeres with ageing is a well-documented observation; however, the reported number of nucleotides in telomeres varies between different laboratories and studies. Such variability is likely caused by ethnic differences between the populations studied. Until now, there were no studies that investigated the variability of telomere length in a senescent Latvian population of the most common mitochondrial haplogroups, defined as H (45%), U (25%), Y chromosomal N1c (40%) and R1a1 (40%). Telomere length was determined in 121 individuals in different age groups, including a control group containing individuals of 20-40 years old and groups of individuals between 60-70 years old, 71-80 years old, 81-90 years old, and above 90 years old. Telomere length was determined using the Southern blot telomeric restriction fragment assay (TRF). Decreased telomere length with ageing was confirmed, but a comparison of centenarians and individuals between 60-90 years of age did not demonstrate a significant difference in telomere length. However, significant variability in telomere length was observed in the control group, indicating probable rapid telomere shortening in some individuals that could lead up to development of health status decline appearing with ageing. Telomere length measured in mononuclear blood cells (MNC) was compared with the telomere length measured in whole peripheral white blood cells (WBC) using TRF. Telomere length in MNC was longer than in WBC for the control group with individuals 20 to 40 years old; in contrast, for the group of individuals aged 65 to 85 years old, measured telomere length was shorter in MNC when compared to WBC.

  19. Consultation and illness behaviour in response to symptoms: a comparison of models from different disciplinary frameworks and suggestions for future research directions.

    Science.gov (United States)

    Wyke, Sally; Adamson, Joy; Dixon, Diane; Hunt, Kate

    2013-06-01

    We all get ill and social scientific interest in how we respond - the study of illness behaviour - continues unabated. Existing models are useful, but have been developed and applied within disciplinary silos, resulting in wasted intellectual and empirical effort and an absence of accumulation of knowledge across disciplines. We present a critical review and detailed comparison of three process models of response to symptoms: the Illness Action Model, the Common Sense Model of the Self-Regulation of Health and Illness and the Network Episode Model. We suggest an integrated framework in which symptoms, responses and actions are simultaneously interpreted and evaluated in the light of accumulated knowledge and through interactions. Evaluation may be subconscious and is influenced by the extent to which the symptoms impose themselves, expectations of outcomes, the resources available and understanding of symptoms' salience and possible outcomes. Actions taken are part of a process of problem solving through which both individuals and their immediate social network seek to (re)achieve 'normality'. Response is also influenced by social structure (directly and indirectly), cultural expectations of health, the meaning of symptoms, and access to and understandings of the legitimate use of services. Changes in knowledge, in embodied state and in emotions can all be directly influential at any point. We do not underestimate the difficulty of operationalising an integrated framework at different levels of analysis. Attempts to do so will require us to move easily between disciplinary understandings to conduct prospective, longitudinal, research that uses novel methodologies to investigate response to symptoms in the context of affective as well as cognitive responses and interactions within social networks. While challenging such an approach would facilitate accumulation of knowledge across disciplines and enable movement beyond description to change in individual and

  20. Cysteamine, zinc, and thiols modify detectability of rat pituitary prolactin: a comparison with effects on bovine prolactin suggests differences in hormone storage

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, L.S.; Lorenson, M.Y.

    1986-03-01

    Little is known about the structure of prolactin (PRL) within secretory granules. Evidence from our previous studies in bovine tissue preparations suggests that control of secretion may reside, in part, in the conversion of storage hormone to releasable PRL. The conversion can be monitored by measuring changes in immunodetectability since the oligomeric, storage form is poorly recognized by antisera raised against monomeric PRL. Since many investigators use rats to study the secretory process and changes in detectability of rat pituitary PRL occur during lactation (depletion-transformation), we undertook the present immunodetectability studies to gain insight into the storage structure of rat (r) PRL. Cysteamine and zinc inhibited tissue PRL immunoassayability in male rat pituitary homogenates and also in partially purified secretory granules as they had inhibited bovine (b) PRL; however, zinc inhibited the rodent hormone less potently than the bovine. In vitro incubation of rat tissue samples without additions resulted in increases in rPRL detectability of up to 84% after 180 minutes; such incubation of bovine samples had no significant effect. A striking additional difference between the species was that exposure to reduced glutathione (GSH), cysteine, homocysteine, mercaptoethanol, and dithiothreitol inhibited rPRL by up to 44%. This compared to thiol stimulation of bPRL by as much as 450%. The inhibitory GSH effect on rPRL was abolished when 0.5% sodium dodecyl sulfate (SDS) was included; in contrast, the stimulatory GSH effect on bPRL did not change with added SDS. SDS alone had no effect on rat homogenate PRL, and only increased rat granule rPRL by 23% compared to its ability to increase bPRL assayability by 44%.

  1. Lie group invariant finite difference schemes for the neutron diffusion equation

    Energy Technology Data Exchange (ETDEWEB)

    Jaegers, P.J.

    1994-06-01

    Finite difference techniques are used to solve a variety of differential equations. For the neutron diffusion equation, the typical local truncation error for standard finite difference approximation is on the order of the mesh spacing squared. To improve the accuracy of the finite difference approximation of the diffusion equation, the invariance properties of the original differential equation have been incorporated into the finite difference equations. Using the concept of an invariant difference operator, the invariant difference approximations of the multi-group neutron diffusion equation were determined in one-dimensional slab and two-dimensional Cartesian coordinates, for multiple region problems. These invariant difference equations were defined to lie upon a cell edged mesh as opposed to the standard difference equations, which lie upon a cell centered mesh. Results for a variety of source approximations showed that the invariant difference equations were able to determine the eigenvalue with greater accuracy, for a given mesh spacing, than the standard difference approximation. The local truncation errors for these invariant difference schemes were found to be highly dependent upon the source approximation used, and the type of source distribution played a greater role in determining the accuracy of the invariant difference scheme than the local truncation error.

  2. The crossroads of anxiety: distinct neurophysiological maps for different symptomatic groups

    Directory of Open Access Journals (Sweden)

    Gerez M

    2016-01-01

    Full Text Available Montserrat Gerez,1–3 Enrique Suárez,2,3 Carlos Serrano,2,3 Lauro Castanedo,2 Armando Tello1,3 1Departamento de Neurofisiología Clínica, Hospital Español de México, Mexico City, Mexico; 2Departamento de Psiquiatría, Hospital Español de México, Mexico City, Mexico; 3Unidad de Postgrado, Universidad Nacional Autónoma de México, Mexico City, Mexico Background: Despite the devastating impact of anxiety disorders (ADs worldwide, long-lasting debates on causes and remedies have not solved the clinician’s puzzle: who should be treated and how? Psychiatric classifications conceptualize ADs as distinct entities, with strong support from neuroscience fields. Yet, comorbidity and pharmacological response suggest a single “serotonin dysfunction” dimension. Whether AD is one or several disorders goes beyond academic quarrels, and the distinction has therapeutic relevance. Addressing the underlying dysfunctions should improve treatment response. By its own nature, neurophysiology can be the best tool to address dysfunctional processes.Purpose: To search for neurophysiological dysfunctions and differences among panic disorder (PD, agoraphobia-social-specific phobia, obsessive–compulsive disorder (OCD and generalized anxiety disorder.Methods: A sample population of 192 unmedicated patients and 30 aged-matched controls partook in this study. Hypothesis-related neurophysiological variables were combined into ten independent factors: 1 dysrhythmic patterns, 2 delta, 3 theta, 4 alpha, 5 beta (whole-head absolute power z-scores, 6 event-related potential (ERP combined latency, 7 ERP combined amplitude (z-scores, 8 magnitude, 9 site, and 10 site of hyperactive networks. Combining single variables into representative factors was necessary because, as in all real-life phenomena, the complexity of interactive processes cannot be addressed through single variables and the multiplicity of potentially implicated variables would demand an extremely large

  3. Group differences in measures of voice production and revised values of maximum airflow declination rate.

    Science.gov (United States)

    Perkell, J S; Hillman, R E; Holmberg, E B

    1994-08-01

    In previous reports, aerodynamic and acoustic measures of voice production were presented for groups of normal male and female speakers [Holmberg et al., J. Acoust. Soc. Am. 84, 511-529 (1988); J. Voice 3, 294-305 (1989)] that were used as norms in studies of voice disorders [Hillman et al., J. Speech Hear. Res. 32, 373-392 (1989); J. Voice 4, 52-63 (1990)]. Several of the measures were extracted from glottal airflow waveforms that were derived by inverse filtering a high-time-resolution oral airflow signal. Recently, the methods have been updated and a new study of additional subjects has been conducted. This report presents previous (1988) and current (1993) group mean values of sound pressure level, fundamental frequency, maximum airflow declination rate, ac flow, peak flow, minimum flow, ac-dc ratio, inferred subglottal air pressure, average flow, and glottal resistance. Statistical tests indicate overall group differences and differences for values of several individual parameters between the 1988 and 1993 studies. Some inter-study differences in parameter values may be due to sampling effects and minor methodological differences; however, a comparative test of 1988 and 1993 inverse filtering algorithms shows that some lower 1988 values of maximum flow declination rate were due at least in part to excessive low-pass filtering in the 1988 algorithm. The observed differences should have had a negligible influence on the conclusions of our studies of voice disorders.

  4. Comparison of Y-STR polymorphisms in three different Slovak population groups.

    Science.gov (United States)

    Petrejcíková, Eva; Siváková, Daniela; Soták, Miroslav; Bernasovská, Jarmila; Bernasovský, Ivan; Rebała, Krzysztof; Boronová, Iveta; Bôziková, Alexandra; Sovicová, Adriana; Gabriková, Dana; Maceková, Sona; Svícková, Petra; Carnogurská, Jana

    2010-01-01

    Eleven Y-chromosomal microsatellite loci included in the Powerplex Y multiplex kit were analyzed in different Slovak population samples: Habans (n = 39), Romanies (n = 100) and Slovak Caucasian (n = 148) individuals, respectively, from different regions of Slovakia. The analysis of molecular variance between populations indicated that 89.27% of the haplotypic variations were found within populations and only 10.72% between populations (Fst = 0.1027; p = 0.0000). The haplotype diversities were ranging from 0.9258 to 0.9978, and indicated a high potential for differentiating between male individuals. The study reports differences in allele frequencies between the Romanies, Habans and Slovak Caucasian men. Selected loci showed that both the Romany and Haban population belonged to endogamous and relatively small founder population groups, which developed in relatively reproductive isolated groups surrounded by the Slovak Caucasian population.

  5. Big Five personality group differences across academic majors: A systematic review

    DEFF Research Database (Denmark)

    Vedel, Anna

    2016-01-01

    literature search identified twelve eligible studies yielding an aggregated sample size of 13,389. Eleven studies reported significant group differences in one or multiple Big Five personality traits. Consistent findings across studies were that students of arts/humanities and psychology scored high......During the past decades, a number of studies have explored personality group differences in the Big Five personality traits among students in different academic majors. To date, though, this research has not been reviewed systematically. This was the aim of the present review. A systematic...... on Neuroticism and Openness; students of political sc. scored high on Openness; students of economics, law, political sc., andmedicine scored high on Extraversion; students ofmedicine, psychology, arts/humanities, and sciences scored high on Agreeableness; and students of arts/humanities scored low...

  6. [Cellulase and xylanase activities of Fusarium Lk:Fr. genus fungi of different trophic groups].

    Science.gov (United States)

    Kurchenko, I M; Sokolova, O V; Zhdanova, N M; Iarynchyn, A M; Iovenko, O M

    2008-01-01

    A comparative analysis of cellulase and xylanase activities of 26 fungal strains of phytopathogenic, saprophytic and endophytic Fusarium species has been realized using the qualitative reactions. The rare of their linear growth on the media with carboxymethyl cellulose or xylane has been studied. It was shown that the fungi of genus Fusarium belonging to different trophic groups possessed low activities of investigated enzymes as a whole, but in endophytic strains their levels were lower than in phytopathogenic ones. At the same time the distinct strain dependence of cellulase and xylanase activities was fixed in the fungi of different trophic groups. As far as the cellulase and xylanase activities in phytopathogenic isolates varied from complete absence to high levels, and since the activity maximum for each of the investigated strains was observed in different growth terms the conclusion was made that the cellulase and xylanase activities could not be considered as possible markers of the fungal isolate pathogenicity on the strain level.

  7. [Antipsychotics of different clinical/pharmacological groups in treatment of negative disorders in schizophrenia].

    Science.gov (United States)

    Danilov, D S

    2014-01-01

    The possibility of using different anti psychotics in treatment of negative disorders in schizophrenia is considered. Mechanisms of the development of "antinegative" effect during treatment with typical neuroleptics, atypical neuroleptics with dopamine-serotonin activity and atypical neuroleptics (partial dopamine receptor agonists) are analyzed. Their efficacy is discussed in the comparative context. In conclusion, a differential approach to schizophrenia treatment is suggested.

  8. Tuning of electronic properties and dynamical stability of graphene oxide with different functional groups

    Science.gov (United States)

    Dabhi, Shweta D.; Jha, Prafulla K.

    2017-09-01

    The structural, electronic and vibrational properties of graphene oxide (GO) with varying proportion of epoxy and hydroxyl functional groups have been studied using density functional theory. The functional groups and oxygen density have an obvious influence on the electronic and vibrational properties. The dependence of band gap on associated functional groups and oxygen density shows a possibility of tuning the band gap of graphene by varying the functional groups as well as oxidation level. The absorption of high oxygen content in graphene leads to the gap opening and resulting in a transition from semimetal to semiconductor. Phonon dispersion curves show no imaginary frequency or no softening of any phonon mode throughout the Brillouin zone which confirms the dynamical stability of all considered GO models. Different groups and different oxygen density result into the varying characteristics of phonon modes. The computed results show good agreement with the experimental observations. Our results present interesting possibilities for engineering the electronic properties of graphene and GO and impact the fabrication of new electronics.

  9. The relationship between personality traits and anxiety/depression levels in different drug abusers' groups.

    Science.gov (United States)

    Tatalović Vorkapić, Sanja; Dadić-Hero, Elizabeta; Ružić, Klementina

    2013-01-01

    Aim. Since psychosocial characteristics of drug abuse involve mainly specific personality and emotional changes, it is very important to investigate characteristics of addictive personality in relationship with emotional state of the individual. Considering that, the objective of this study was to analyse the relationship between personality structure and emotional state of two different groups: heroin addicts and recreate drug abusers. Methods. The total of 288 (219 males and 69 females; 191 heroin addicts and 97 recreate drug users) clients of Centre for the prevention and treatment of drug abuse in Rijeka completed Eysenck's Personality Questionnaire (EPQ R/A), Beck's Anxiety Inventory (BAI) and Beck's Depression Inventory (BDI). Their average age was 22. Results. In the group of heroin addicts, higher levels of anxiety and depression were significantly correlated with higher levels of psychoticism, neuroticism, criminality and addiction. In the group of recreate drug users, higher extraversion and social conformity were determined. Furthermore, in the first group was found even higher depression. However when the anxiety level was compared between these two groups, there was no significant difference. Conclusion. Overall, the findings implied that the used measurement instruments could serve as the useful diagnostic tools that could ensure advantageous treatment directions.

  10. The relationship between personality traits and anxiety/depression levels in different drug abusers' groups

    Directory of Open Access Journals (Sweden)

    Tatalović Vorkapić Sanja

    2013-12-01

    Full Text Available AIM: Since psychosocial characteristics of drug abuse involve mainly specific personality and emotional changes, it is very important to investigate characteristics of addictive personality in relationship with emotional state of the individual. Considering that, the objective of this study was to analyse the relationship between personality structure and emotional state of two different groups: heroin addicts and recreate drug abusers. METHODS: The total of 288 (219 males and 69 females; 191 heroin addicts and 97 recreate drug users clients of Centre for the prevention and treatment of drug abuse in Rijeka completed Eysenck's Personality Questionnaire (EPQ R/A, Beck's Anxiety Inventory (BAI and Beck's Depression Inventory (BDI. Their average age was 22. RESULTS: In the group of heroin addicts, higher levels of anxiety and depression were significantly correlated with higher levels of psychoticism, neuroticism, criminality and addiction. In the group of recreate drug users, higher extraversion and social conformity were determined. Furthermore, in the first group was found even higher depression. However when the anxiety level was compared between these two groups, there was no significant difference. CONCLUSION: Overall, the findings implied that the used measurement instruments could serve as the useful diagnostic tools that could ensure advantageous treatment directions.

  11. The Difference of Food Pattern and Physical Acti vity between Obese and Non Obese Teenage Group.

    Directory of Open Access Journals (Sweden)

    Kartika Suryaputra

    2012-06-01

    Full Text Available Obesity in teenage is a syndrome that happened because of fat accumulation in the body. Obesity occured because of complex interaction between parental fatness, food pattern, and physical activity. In Indonesia, prevalence of teenage obesity is gradually increasing. The aim of this research was to analyze about the difference of foodpattern and physical activity between obesity and non obesity teenage group. This study was an analytical observational research with cross sectional design. The samples were 40 teenage from Santa Agnes seniorhigh school Surabaya (age 15-17 that was taken by simple random sampling, that divers to 20 obese and 20 non obese teenage group. The data were analysed by Mann Whitney test for nutrition knowledge, pocket money, food pattern, fast food’s consumption, snack’s consumption pattern, consumption level of energy, carbohydrat, protein, and fat, physical activity and parental fatness. The result of the statistic test showed that variables significant difference are nutrition knowledge, pocket money, food pattern, fastfood’s consumption, snack’s consumption pattern, energy consumption level, carbohydrate consumption level, protein consumption level, fat consumption level, physical activity and parental fatness between obese and non obese teenage group. The conlusion is that significant differences are food pattern and physical activity between obese and non obese teenage group. Recommendation is necessary to provide information and education to teenage about healthy food and adequate physical activity to prevent obesity

  12. Differences in presence and distribution of various food groups in persons with spinal cord injury

    Directory of Open Access Journals (Sweden)

    Ivana Kinkorová

    2017-06-01

    Full Text Available The aim of this study was to analyse the dietary habits of subjects with spinal cord injury (SCI, especially to evaluate differences in the presence and distribution of various food groups among a group of males and females. Subjects (n = 50, n1 = 36 males, n2 = 14 females completed a frequency questionnaire, which included questions focused on the detection of size of consumed foods and frequency of consumption of various food groups (cereals, potatoes, vegetables, fruits, dairy products, meat, meat products, fats, sweets. We noted significant differences in the composition of breakfast (meat intake, lunch (vegetable intake, dairy intake, dinner (dairy intake, sweet intake, snacks (fats intake in males and females. Differences in dietary habits of males and females with SCI especially concerned sizes of consumed servings of food, but also the representation of individual food groups in the diet throughout the day. In this context, the adapted food pyramid can be used as a visual tool to facilitate understanding and the maintenance of a healthy diet.

  13. Cephalometric and anthropometric data of obstructive apnea in different age groups

    Directory of Open Access Journals (Sweden)

    Paulo de Tarso Moura Borges

    2015-02-01

    Full Text Available Introduction: Patients with obstructive sleep apnea syndrome usually present with changes in upper airway morphology and/or body fat distribution, which may occur throughout life and increase the severity of obstructive sleep apnea syndrome with age. Objective: To correlate cephalometric and anthropometric measures with obstructive sleep apnea syndrome severity in different age groups. Methods: A retrospective study of cephalometric and anthropometric measures of 102 patients with obstructive sleep apnea syndrome was analyzed. Patients were divided into three age groups (≥20 and <40 years, ≥40 and <60 years, and ≥60 years. Pearson's correlation was performed for these measures with the apnea-hypopnea index in the full sample, and subsequently by age group. Results: The cephalometric measures MP-H (distance between the mandibular plane and the hyoid bone and PNS-P (distance between the posterior nasal spine and the tip of the soft palate and the neck and waist circumferences showed a statistically significant correlation with apnea-hypopnea index in both the full sample and in the ≥40 and <60 years age group. These variables did not show any significant correlation with the other two age groups (<40 and ≥60 years. Conclusion: Cephalometric measurements MP-H and PNS-P and cervical and waist circumfer- ences correlated with obstructive sleep apnea syndrome severity in patients in the ≥40 and <60 age group.

  14. Cephalometric and anthropometric data of obstructive apnea in different age groups.

    Science.gov (United States)

    Borges, Paulo de Tarso Moura; Silva, Benedito Borges da; Moita Neto, José Machado; Borges, Núbia Evangelista de Sá; Li, Li M

    2015-01-01

    Patients with obstructive sleep apnea syndrome usually present with changes in upper airway morphology and/or body fat distribution, which may occur throughout life and increase the severity of obstructive sleep apnea syndrome with age. To correlate cephalometric and anthropometric measures with obstructive sleep apnea syndrome severity in different age groups. A retrospective study of cephalometric and anthropometric measures of 102 patients with obstructive sleep apnea syndrome was analyzed. Patients were divided into three age groups (≥20 and <40 years, ≥40 and <60 years, and ≥60 years). Pearson's correlation was performed for these measures with the apnea-hypopnea index in the full sample, and subsequently by age group. The cephalometric measures MP-H (distance between the mandibular plane and the hyoid bone) and PNS-P (distance between the posterior nasal spine and the tip of the soft palate) and the neck and waist circumferences showed a statistically significant correlation with apnea-hypopnea index in both the full sample and in the ≥40 and <60 years age group. These variables did not show any significant correlation with the other two age groups (<40 and ≥60 years). Cephalometric measurements MP-H and PNS-P and cervical and waist circumferences correlated with obstructive sleep apnea syndrome severity in patients in the ≥40 and <60 age group. Copyright © 2014 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  15. Subject domain differences in secondary school teachers' attitudes towards grouping pupils by ability

    Directory of Open Access Journals (Sweden)

    Hallam Susan

    2008-01-01

    Full Text Available Previous research has revealed that teachers' attitudes to ability grouping are influenced by the type of ability grouping adopted in the school where they teach. This research aimed to compare the attitudes of teachers of different subjects teaching low, high or mixed ability classes in years 7 to 9 in 45 secondary schools. Over 1500 teachers from 45 secondary schools, with a range of subject specialisms completed a questionnaire which elicited their responses to statements of beliefs about ability grouping and its effects. Teachers of mathematics and modern foreign languages were more in favour of structured ability grouping than those teaching English and humanities. Science, arts and PE, and ICT, design and business studies teachers expressed intermediate attitudes. Attitudes were determined in part by conceptions of the nature of the subject but also by the type of ability groupings adopted by the school in which they taught. In taking decisions about the type of ability grouping to adopt consideration needs to be given to the nature of the subject matter to be taught and the attitudes of the teachers who teach that subject.

  16. RR Lyrae Luminosity Differences between Oosterhoff Group I and II Cluster Systems and the Origin of the Oosterhoff Dichotomy

    Science.gov (United States)

    Lee, Jae-Woo; Carney, Bruce W.

    1999-09-01

    We present a comparative study of the Oosterhoff II cluster M2 and the Oosterhoff I cluster M3. Both have similar metallicities, [Fe/H]=-1.62 for M2 and -1.66 for M3, but very different horizontal-branch (HB) morphologies (B-R)/(B+V+R)=0.92 for M2 and 0.08 for M3. A period shift analysis and main-sequence fitting show that RRab variables in M2 are about 0.2 mag brighter than those in M3. Comparisons of the M2 period shift with Oosterhoff I clusters NGC 3201 and NGC 7006 also yield similar results, while a comparison between M2 and the Oosterhoff II cluster NGC 5986 reveals that the RR Lyrae luminosities are very similar. The luminosity difference is thought to be due to the evolutionary effect described in 1990 by Lee, Demarque, & Zinn: the M2 RRab variables have evolved away from the zero-age horizontal branch (ZAHB), while most M3 RRab variables lie near the ZAHB. A comparison of the mean period change rates of two clusters supports this hypothesis. Our relative age estimation using the difference in color between the base of giant branch and turn-off point shows that M2 is about 2 Gyr older than M3. Our result strongly suggests that the Oosterhoff dichotomy is due to age differences between Oosterhoff group I and II. This is consistent with the idea that the global second parameter is age. We discuss the kinematic differences between Oosterhoff group I and II clusters. Our result shows that the Oosterhoff group I clusters have zero or retrograde rotation with =-68+/-56 km s^-1 and sigma_los=131+/-28 km s^-1, while the Oosterhoff group II clusters have prograde rotation with =+94+/-47 km s^-1 and sigma_los=115+/-29 km s^-1, confirming a similar conclusion of van den Bergh. The difference in kinematics and ages between Oosterhoff group I and II clusters suggests that they may have different origins: The Oosterhoff II clusters were formed very early in the proto-Galaxy while the Oosterhoff I clusters were formed at different locations and at a later time, and were

  17. Geochemical characteristics of different maceral groups in the Huangxian Coal,China

    Institute of Scientific and Technical Information of China (English)

    CAI Zhen-yu; WANG Jin-xi; JIN Yu-jie; ZHANG Hong-jian; JIN Kan-kun

    2004-01-01

    In order to research how lignite is utilized, two coal samples of seams 2 and 4were taken from the Huangxian Basin, China. The samples were separated into vitrinite,sporinite, and resinite. Geo-chemical and pyrolysis methods were used to analyse three maceral groups and two seam samples. The results indicate that the resinite and sporinite groups have higher extract yields, S1, S2, HI values, and pyrolysis compounds.These differences may shed light on the usage of the Huangxian lignite. Seam 2 produces more gas and oil than seam 4 does because seam 2 contains more resinite and sporinite macerals.

  18. Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design.

    Science.gov (United States)

    Ping, Li-Hua; Joseph, Sarah B; Anderson, Jeffrey A; Abrahams, Melissa-Rose; Salazar-Gonzalez, Jesus F; Kincer, Laura P; Treurnicht, Florette K; Arney, Leslie; Ojeda, Suany; Zhang, Ming; Keys, Jessica; Potter, E Lake; Chu, Haitao; Moore, Penny; Salazar, Maria G; Iyer, Shilpa; Jabara, Cassandra; Kirchherr, Jennifer; Mapanje, Clement; Ngandu, Nobubelo; Seoighe, Cathal; Hoffman, Irving; Gao, Feng; Tang, Yuyang; Labranche, Celia; Lee, Benhur; Saville, Andrew; Vermeulen, Marion; Fiscus, Susan; Morris, Lynn; Karim, Salim Abdool; Haynes, Barton F; Shaw, George M; Korber, Bette T; Hahn, Beatrice H; Cohen, Myron S; Montefiori, David; Williamson, Carolyn; Swanstrom, Ronald

    2013-07-01

    Understanding human immunodeficiency virus type 1 (HIV-1) transmission is central to developing effective prevention strategies, including a vaccine. We compared phenotypic and genetic variation in HIV-1 env genes from subjects in acute/early infection and subjects with chronic infections in the context of subtype C heterosexual transmission. We found that the transmitted viruses all used CCR5 and required high levels of CD4 to infect target cells, suggesting selection for replication in T cells and not macrophages after transmission. In addition, the transmitted viruses were more likely to use a maraviroc-sensitive conformation of CCR5, perhaps identifying a feature of the target T cell. We confirmed an earlier observation that the transmitted viruses were, on average, modestly underglycosylated relative to the viruses from chronically infected subjects. This difference was most pronounced in comparing the viruses in acutely infected men to those in chronically infected women. These features of the transmitted virus point to selective pressures during the transmission event. We did not observe a consistent difference either in heterologous neutralization sensitivity or in sensitivity to soluble CD4 between the two groups, suggesting similar conformations between viruses from acute and chronic infection. However, the presence or absence of glycosylation sites had differential effects on neutralization sensitivity for different antibodies. We suggest that the occasional absence of glycosylation sites encoded in the conserved regions of env, further reduced in transmitted viruses, could expose specific surface structures on the protein as antibody targets.

  19. Joint source based morphometry identifies linked gray and white matter group differences.

    Science.gov (United States)

    Xu, Lai; Pearlson, Godfrey; Calhoun, Vince D

    2009-02-01

    We present a multivariate approach called joint source based morphometry (jSBM), to identify linked gray and white matter regions which differ between groups. In jSBM, joint independent component analysis (jICA) is used to decompose preprocessed gray and white matter images into joint sources and statistical analysis is used to determine the significant joint sources showing group differences and their relationship to other variables of interest (e.g. age or sex). The identified joint sources are groupings of linked gray and white matter regions with common covariation among subjects. In this study, we first provide a simulation to validate the jSBM approach. To illustrate our method on real data, jSBM is then applied to structural magnetic resonance imaging (sMRI) data obtained from 120 chronic schizophrenia patients and 120 healthy controls to identify group differences. JSBM identified four joint sources as significantly associated with schizophrenia. Linked gray-white matter regions identified in each of the joint sources included: 1) temporal--corpus callosum, 2) occipital/frontal--inferior fronto-occipital fasciculus, 3) frontal/parietal/occipital/temporal--superior longitudinal fasciculus and 4) parietal/frontal--thalamus. Age effects on all four joint sources were significant, but sex effects were significant only for the third joint source. Our findings demonstrate that jSBM can exploit the natural linkage between gray and white matter by incorporating them into a unified framework. This approach is applicable to a wide variety of problems to study linked gray and white matter group differences.

  20. Differences in outcomes between GOLD groups in patients with COPD in the TIOSPIR® trial

    Directory of Open Access Journals (Sweden)

    Dusser D

    2016-01-01

    patients, respectively.Conclusion: The data obtained from the TIOSPIR® trial, supporting earlier studies, suggest that proportionally more CV medication and CV deaths occur in GOLD Group B COPD patients, although deaths attributed to respiratory causes are more prevalent in Groups C and D. Keywords: TIOSPIR®, GOLD, cardiovascular comorbidity, mortality, respiratory death, cardiovascular death

  1. [Effects of Meek skin grafting on patients with extensive deep burn at different age groups].

    Science.gov (United States)

    Di, H P; Niu, X H; Li, Q; Li, X L; Xue, J D; Cao, D Y; Han, D W; Xia, C D

    2017-03-20

    Objective: To investigate the effect of Meek skin grafting on patients with extensive deep burn at different age groups. Methods: Eighty-four patients with extensive deep burns conforming to the study criteria were hospitalized in our unit from April 2011 to April 2015. Patients were divided into children group (C, with age less than 12 years old), young and middle-aged group (YM, with age more than 18 years and less than 50 years old), and old age group (O, with age more than 55 years old) according to age, with 28 patients in each group. All patients received Meek skin grafting treatment. The use of autologous skin area, operation time, wound healing time, and hospitalization time were recorded. The survival rate of skin graft on post operation day 7, complete wound healing rate in post treatment week 2, and the mortality were calculated. Data were processed with one-way analysis of variance, t test, and χ(2) test. Results: The use of autologous skin area of patients in group C was (5.1±1.0)% total body surface area (TBSA), significantly less than (8.3±1.0)%TBSA and (8.3±1.4)%TBSA in groups YM and O, respectively (with t values 32.900 and 52.624, respectively, P values below 0.05). The operation time, wound healing time, and hospitalization time of patients in group C were (1.368±0.562) h, (9.6±0.6) and (32±11) d, significantly shorter than those in group YM [(3.235±0.011) h, (16.9±2.6) and (48±12) d, respectively] and group O [(3.692±0.481) h, (17.3±2.6) and (46±13) d, respectively, with t values from 4.350 to 21.160, P values below 0.05]. The survival rate of skin graft of patients on post operation day 7 in group C was (92±15)%, significantly higher than (81±10)% and (72±12)% in groups YM and O, respectively (with t values 5.509 and 3.229, respectively, P values below 0.05). The above indexes in groups YM and O were similar (with t values from 0.576 to 22.958, P values above 0.05). Complete wound healing rate in post treatment week 2 and the

  2. The impact of global warming on the range distribution of different climatic groups of Aspidoscelis costata costata.

    Science.gov (United States)

    Güizado-Rodríguez, Martha Anahí; Ballesteros-Barrera, Claudia; Casas-Andreu, Gustavo; Barradas-Miranda, Victor Luis; Téllez-Valdés, Oswaldo; Salgado-Ugarte, Isaías Hazarmabeth

    2012-12-01

    The ectothermic nature of reptiles makes them especially sensitive to global warming. Although climate change and its implications are a frequent topic of detailed studies, most of these studies are carried out without making a distinction between populations. Here we present the first study of an Aspidoscelis species that evaluates the effects of global warming on its distribution using ecological niche modeling. The aims of our study were (1) to understand whether predicted warmer climatic conditions affect the geographic potential distribution of different climatic groups of Aspidoscelis costata costata and (2) to identify potential altitudinal changes of these groups under global warming. We used the maximum entropy species distribution model (MaxEnt) to project the potential distributions expected for the years 2020, 2050, and 2080 under a single simulated climatic scenario. Our analysis suggests that some climatic groups of Aspidoscelis costata costata will exhibit reductions and in others expansions in their distribution, with potential upward shifts toward higher elevation in response to climate warming. Different climatic groups were revealed in our analysis that subsequently showed heterogeneous responses to climatic change illustrating the complex nature of species geographic responses to environmental change and the importance of modeling climatic or geographic groups and/or populations instead of the entire species' range treated as a homogeneous entity.

  3. Differences in nutrient requirements imply a non-linear emergence of leaders in animal groups.

    Directory of Open Access Journals (Sweden)

    Cédric Sueur

    Full Text Available Collective decision making and especially leadership in groups are among the most studied topics in natural, social, and political sciences. Previous studies have shown that some individuals are more likely to be leaders because of their social power or the pertinent information they possess. One challenge for all group members, however, is to satisfy their needs. In many situations, we do not yet know how individuals within groups distribute leadership decisions between themselves in order to satisfy time-varying individual requirements. To gain insight into this problem, we build a dynamic model where group members have to satisfy different needs but are not aware of each other's needs. Data about needs of animals come from real data observed in macaques. Several studies showed that a collective movement may be initiated by a single individual. This individual may be the dominant one, the oldest one, but also the one having the highest physiological needs. In our model, the individual with the lowest reserve initiates movements and decides for all its conspecifics. This simple rule leads to a viable decision-making system where all individuals may lead the group at one moment and thus suit their requirements. However, a single individual becomes the leader in 38% to 95% of cases and the leadership is unequally (according to an exponential law distributed according to the heterogeneity of needs in the group. The results showed that this non-linearity emerges when one group member reaches physiological requirements, mainly the nutrient ones - protein, energy and water depending on weight - superior to those of its conspecifics. This amplification may explain why some leaders could appear in animal groups without any despotism, complex signalling, or developed cognitive ability.

  4. Grain yield of coffee conilon different maturity groups by REML / BLUP

    Directory of Open Access Journals (Sweden)

    Cíntia Machado de Oliveira Moulin Carias

    2014-02-01

    Full Text Available This study aimed to estimate genetic parameters and evaluate the grain yield clones coffee Conilon three maturity groups by REML / BLUP. We studied 20 clones of coffee Conilon early ripening, maturation 20 intermediate and 20 late maturing for the characteristic grain yield. For each group, represented by different times of ripening of fruits installed an experiment was conducted in a randomized block design with four replications, plots with five plants spaced 3.0 m X 1.2 m with 2777 plantas/ha-1e evaluations were made in the years 2006, 2007, 2008 and 2009, during harvest, conducted and ceded by the Institute Capixaba Research, Technical Assistance and Rural Extension (Incaper. The average heritability (0.28, 0.38 and the value of accuracy (0.68, 0.69 of clone selection were higher for the group of early and intermediate maturity, respectively. In the late group, the experimental accuracy was not satisfactory and therefore, a low accuracy in inference about the mean genotypic, reflecting the difficulty of selection. Clones 14 and 17 of the early group and 20, 14 and 17 of the intermediate group occupied the first places in the middle of the feature and productivity were also allocated in the same positions for MHVG (Genetic Stability of Values, PRVG (Adaptability of Genetic Values and MHPRVG (Stability and Adaptability of Genetic Values, indicating a high yield, stability and adaptability to variations in four crops for these genotypes. The interaction clones x crops was significant for the three maturity groups, characterizing a complex type of interaction, which is problematic for the breeder due to inconsistency of the superiority of clones against variations of crops. The combined results showed superiority of the group over the intermediate early and late.

  5. What Makes a Difference for Disadvantaged Girls? Investigating the Interplay between Group Composition and Positive Youth Development in Sport

    Directory of Open Access Journals (Sweden)

    Hebe Schaillée

    2015-06-01

    Full Text Available It has been suggested that group composition can influence the experiences of individual group members in social programmes (Weiss, 1998. The purpose of the present study was to examine the relationship between peer group composition in sports programmes and positive youth development (PYD in disadvantaged girls, as well as to determine whether it was moderated by personal characteristics. Two hundred young women aged between 10 and 24 completed a questionnaire including, among others, the “Youth Experience Survey for Sport” (YES-S (MacDonald, Côté, Eys, & Deakin, 2012 and questions regarding participants’ socio-economic characteristics (i.e., nationality, education, family situation. Multilevel regression analyses were performed to take into account the hierarchical data structure. At the group level, a higher percentage of girls from a low educational track and with a migration background predicted greater PYD, as indicated by higher levels of personal and social skills, cognitive skills and goal setting. Results showed interaction effects between the respondents’ family structures on the participant and team levels. The overall statistical models for the different developmental domains accounted for variance ranging from 14.7% (personal and social skills to 30.3% (cognitive skills. Results indicated that the extent to which disadvantaged girls derive benefits from their participation in sport also depends on the group composition. The interaction effects between the group composition and individual characteristics suggest that when girls participate in a group of similar peers, those from non-intact families will derive more benefits than their counterparts from intact families.

  6. What Makes a Difference for Disadvantaged Girls? Investigating the Interplay between Group Composition and Positive Youth Development in Sport

    Directory of Open Access Journals (Sweden)

    Hebe Schaillée

    2015-06-01

    Full Text Available It has been suggested that group composition can influence the experiences of individual group members in social programmes (Weiss, 1998. The purpose of the present study was to examine the relationship between peer group composition in sports programmes and positive youth development (PYD in disadvantaged girls, as well as to determine whether it was moderated by personal characteristics. Two hundred young women aged between 10 and 24 completed a questionnaire including, among others, the “Youth Experience Survey for Sport” (YES-S (MacDonald, Côté, Eys, & Deakin, 2012 and questions regarding participants’ socio-economic characteristics (i.e., nationality, education, family situation. Multilevel regression analyses were performed to take into account the hierarchical data structure. At the group level, a higher percentage of girls from a low educational track and with a migration background predicted greater PYD, as indicated by higher levels of personal and social skills, cognitive skills and goal setting. Results showed interaction effects between the respondents’ family structures on the participant and team levels. The overall statistical models for the different developmental domains accounted for variance ranging from 14.7% (personal and social skills to 30.3% (cognitive skills. Results indicated that the extent to which disadvantaged girls derive benefits from their participation in sport also depends on the group composition. The interaction effects between the group composition and individual characteristics suggest that when girls participate in a group of similar peers, those from non-intact families will derive more benefits than their counterparts from intact families.

  7. A micrometeorological technique for detecting small differences in methane emissions from two groups of cattle

    Science.gov (United States)

    Laubach, Johannes; Grover, Samantha P. P.; Pinares-Patiño, Cesar S.; Molano, German

    2014-12-01

    Potential approaches for reducing enteric methane (CH4) emissions from cattle will require verification of their efficacy at the paddock scale. We designed a micrometeorological approach to compare emissions from two groups of grazing cattle. The approach consists of measuring line-averaged CH4 mole fractions upwind and downwind of each group and using a backward-Lagrangian stochastic model to compute CH4 emission rates from the observed mole fractions, in combination with turbulence statistics measured by a sonic anemometer. With careful screening for suitable wind conditions, a difference of 10% in group emission rates could be detected. This result was corroborated by simultaneous measurements of daily CH4 emissions from each animal with the sulfur hexafluoride (SF6) tracer-ratio technique.

  8. The effect of hydroxyl group on the electronic structure of carbon nanotubes with different diameters

    Science.gov (United States)

    Kheirmand, M.

    2016-09-01

    A single hydroxyl group is functionalized on both sides of one ring of several carbon nanotubes (CNT) as CNT-OH. The electronic structure and chemical bonding parameters are studied with the help of quantum theory of atoms in molecules (QTAIM). Anionic states of the CNT-O as deprotonated hydroxyl are studied in order to get insight into the nature of CNT-OH species, considering frozen and relaxed geometries of CNT-O compounds. The results show a significant difference between inside or outside substituted hydroxyl groups; and also complicated behavior of the CNT's diameter, and it can be concluded that hydroxyl group can be used to tune the CNT's properties, effectively, in interesting application of these nanostructures.

  9. Ethnic group differences in cardiovascular risk assessment scores: national cross-sectional study.

    Science.gov (United States)

    Dalton, Andrew R H; Bottle, Alex; Soljak, Michael; Majeed, Azeem; Millett, Christopher

    2014-08-01

    There are marked inequalities in cardiovascular disease (CVD) incidence and outcomes between ethnic groups. CVD risk scores are increasingly used in preventive medicine and should aim to accurately reflect differences between ethnic groups. Ethnicity, as an independent risk factor for CVD, can be accounted for in CVD risk scores primarily using two methods, either directly incorporating it as a risk factor in the algorithm or through a post hoc adjustment of risk. We aim to compare these two methods in terms of their prediction of CVD across ethnic groups using representative national data from England. A cross-sectional study using data from the Health Survey for England. We measured ethnic group differences in risk estimation between the QRISK2, which includes ethnicity and Joint British Societies 2 (JBS2) algorithm, which uses post hoc risk adjustment factor for South Asian men. The QRISK2 score produces lower median estimates of CVD risk than JBS2 overall (6.6% [lower quartile-upper quartile (LQ-UQ)=4.0-18.6] compared with 9.3% [LQ-UQ=2.3-16.9]). Differences in median risk scores are significantly greater in South Asian men (7.5% [LQ-UQ=3.6-12.5]) compared with White men (3.0% [LQ-UQ=0.7-5.9]). Using QRISK2, 19.1% [95% confidence interval (CI)=16.2-22.0] fewer South Asian men are designated at high risk compared with 8.8% (95% CI=5.9-7.8) fewer in White men. Across all ethnic groups, women had a lower median QRISK2 score (0.72 [LQ-UQ=- 0.6 to 2.13]), although relatively more (2.0% [95% CI=1.4-2.6]) were at high risk than with JBS2. Ethnicity is an important CVD risk factor. Current scoring tools used in the UK produce significantly different estimates of CVD risk within ethnic groups, particularly in South Asian men. Work to accurately estimate CVD risk in ethnic minority groups is important if CVD prevention programmes are to address health inequalities.

  10. Use of an Innovative Personality-Mindset Profiling Tool to Guide Culture-Change Strategies among Different Healthcare Worker Groups.

    Directory of Open Access Journals (Sweden)

    M Lindsay Grayson

    Full Text Available Important culture-change initiatives (e.g. improving hand hygiene compliance are frequently associated with variable uptake among different healthcare worker (HCW categories. Inherent personality differences between these groups may explain change uptake and help improve future intervention design.We used an innovative personality-profiling tool (ColourGrid® to assess personality differences among standard HCW categories at five large Australian hospitals using two data sources (HCW participant surveys [PS] and generic institution-wide human resource [HR] data to: a compare the relative accuracy of these two sources; b identify differences between HCW groups and c use the observed profiles to guide design strategies to improve uptake of three clinically-important initiatives (improved hand hygiene, antimicrobial stewardship and isolation procedure adherence.Results from 34,243 HCWs (HR data and 1045 survey participants (PS data suggest that HCWs were different from the general population, displaying more individualism, lower power distance, less uncertainty avoidance and greater cynicism about advertising messages. HR and PS data were highly concordant in identifying differences between the three key HCW categories (doctors, nursing/allied-health, support services and predicting appropriate implementation strategies. Among doctors, the data suggest that key messaging should differ between full-time vs part-time (visiting senior medical officers (SMO, VMO and junior hospital medical officers (HMO, with SMO messaging focused on evidence-based compliance, VMO initiatives emphasising structured mandatory controls and prestige loss for non-adherence, and for HMOs focusing on leadership opportunity and future career risk for non-adherence.Compared to current standardised approaches, targeted interventions based on personality differences between HCW categories should result in improved infection control-related culture-change uptake. Personality

  11. [THE PERCENTAGE OF BLOOD SERUM TESTS WITH HEMOLYSIS IN DIFFERENT GROUPS OF PATIENTS].

    Science.gov (United States)

    Moshkin, A V

    2015-06-01

    In the process of laboratory analysis most of the errors occur at the pre-analytical stage. The percentage of blood serum tests with hemolysis is largely applied as an indicator of quality of sampling and transport of blood tests in laboratory. The study was carried out to analyze percentage of tests with hemolysis in different groups of in- and out-patients. The percentage of tests with hemolysis was estimated according actual recommendation of IFCC working group "Laboratory Errors and Patient Safety" as percentage oftests with free hemoglobin more than 0.5 g/l of total amount of serum tests analyzed on biochemical analyzer capable to measure hemolysis index. The hemolysis was identified in 199 (1.4%) out of 14 170 samples. The large dispersion of results in different groups of patient was established. In children younger than 7 years treated in hospital percentage of hemolysis amounted to 2.44%, in patients of reanimation department - 2.38%. In adult patients of hospital this indicator of quality ranged from 0.31% to 1.59%. In two groups of out-patients this indicator amounted to 0.36% (clinic personnel, dispensarization) and 1.81% (out-patients). Such a dispersion complicates inter-laboratory comparison of quality according this particular indicator. The necessity is substantiated to apply more efforts concerning harmonization of indicators of quality in laboratory medicine.

  12. Conclusions Regarding Cross-Group Differences in Happiness Depend on Difficulty of Reaching Respondents*

    Science.gov (United States)

    Heffetz, Ori; Rabin, Matthew

    2015-01-01

    A growing literature explores differences in subjective well-being across demographic groups, often relying on surveys with high nonresponse rates. By using the reported number of call attempts made to participants in the University of Michigan’s Surveys of Consumers, we show that comparisons among easy-to-reach respondents differ from comparisons among hard-to-reach ones. Notably, easy-to-reach women are happier than easy-to-reach men, but hard-to-reach men are happier than hard-to-reach women, and conclusions of a survey could reverse with more attempted calls. Better alternatives to comparing group sample averages might include putting greater weight on hard-to-reach respondents or even extrapolating trends in responses. PMID:26316655

  13. Ultrasensitive optical microfiber coupler based sensors operating near the turning point of effective group index difference

    Science.gov (United States)

    Li, Kaiwei; Zhang, Ting; Liu, Guigen; Zhang, Nan; Zhang, Mengying; Wei, Lei

    2016-09-01

    We propose and study an optical microfiber coupler (OMC) sensor working near the turning point of effective group index difference between the even supermode and odd supermode to achieve high refractive index (RI) sensitivity. Theoretical calculations reveal that infinite sensitivity can be obtained when the measured RI is close to the turning point value. This diameter-dependent turning point corresponds to the condition that the effective group index difference equals zero. To validate our proposed sensing mechanism, we experimentally demonstrate an ultrahigh sensitivity of 39541.7 nm/RIU at a low ambient RI of 1.3334 based on an OMC with the diameter of 1.4 μm. An even higher sensitivity can be achieved by carrying out the measurements at RI closer to the turning point. The resulting ultrasensitive RI sensing platform offers a substantial impact on a variety of applications from high performance trace analyte detection to small molecule sensing.

  14. Level of choreographic preparedness of sportsmen of different age groups in sports aerobics

    Directory of Open Access Journals (Sweden)

    Valentina Todorova

    2016-08-01

    Full Text Available Purpose: the analysis of choreographic preparedness of different age groups of sportsmen on sports aerobics. Material & Methods: videos of competitive programs of the sportsmen, who are specialized in aerobics, different age groups, method of expert evaluations are used for the quantitative analysis of choreographic preparedness; methods of mathematical analysis and synthesis are used for the determination of level of choreographic preparedness of sportsmen. Results: the level of choreographic preparedness is determined on the basis of the rating scale of the criteria of implementation of the competitive programs (Competition rules of 2013–2016 of teams-participants of the Championship of Ukraine for sports aerobics. Conclusions: indicators, to which it is necessary to pay attention in the course of choreographic preparation at stages of long-term training of sportsmen, are defined.

  15. Adolescent Substance Use Groups: Antecedent and Concurrent Personality Differences in a Longitudinal Study

    DEFF Research Database (Denmark)

    Oliva, E. M.; Keyes, M.; Iacono, W. G.;

    2012-01-01

    personality and age-18 substance use in a community sample of 1,298 twins (96% Caucasian, 49% male). Personality measures at ages 11 and 18 assessed positive emotionality (agentic and communal), negative emotionality, and constraint. Substance use groupsabstainers, experimenters, and problem userswere created......This study attempted to extend Shedler and Block's () influential study, which found that adolescent drug experimenters had the healthiest personality functioning compared to abstainers and frequent users. Using a prospective design, we examined the relationship between antecedent and concurrent...... at age 18. Age-18 substance use groups differed in age-11 and age-18 constraint such that problem users were lower than experimenters, who were lower than abstainers. Age-18 substance use groups did not differ in age-18 positive emotionality. However, abstainers were significantly lower than...

  16. Conclusions Regarding Cross-Group Differences in Happiness Depend on Difficulty of Reaching Respondents.

    Science.gov (United States)

    Heffetz, Ori; Rabin, Matthew

    2013-12-01

    A growing literature explores differences in subjective well-being across demographic groups, often relying on surveys with high nonresponse rates. By using the reported number of call attempts made to participants in the University of Michigan's Surveys of Consumers, we show that comparisons among easy-to-reach respondents differ from comparisons among hard-to-reach ones. Notably, easy-to-reach women are happier than easy-to-reach men, but hard-to-reach men are happier than hard-to-reach women, and conclusions of a survey could reverse with more attempted calls. Better alternatives to comparing group sample averages might include putting greater weight on hard-to-reach respondents or even extrapolating trends in responses.

  17. Expectations of students of different age groups in Agricultural Technician the Professional Education

    Directory of Open Access Journals (Sweden)

    Vanderlei Both

    2013-09-01

    Full Text Available It is proposed from this investigative study to analyze the expectations of entering students of technical course in Agriculture, with different age groups, as the contribution of professional education for its professionalism and continued education. A mixed questionnaire was applied and, to evaluate the data, the group was divided into two categories. Differences in their school history were evidenced, as well as their expectations regarding the course. The younger students have a tendency to be conducting the course because they could not join a college. On the other hand, older students seek in technical knowledge to act professionally or to be a complement of their graduation. Thus, the teachers and the school need to strengthen the possibilities that the course provide, in order to stimulate the course ending, in order to form professionals to contribute to the community.

  18. Genetic affinity among five different population groups in India reflecting a Y-chromosome gene flow.

    Science.gov (United States)

    Saha, Anjana; Sharma, Swarkar; Bhat, Audesh; Pandit, Awadesh; Bamezai, Ramesh

    2005-01-01

    Four binary polymorphisms and four multiallelic short tandem repeat (STR) loci from the nonrecombining region of the human Y-chromosome were typed in different Indian population groups from Uttar Pradeh (UP), Bihar (BI), Punjab (PUNJ), and Bengal (WB) speaking the Indo-Aryan dialects and from South India (SI) with the root in the Dravidian language. We identified four major haplogroups [(P) 1+, (C and F) 2+, (R1a) 3, (K) 26+] and 114 combinations of Y-STR haplotypes. Analyses of the haplogroups indicated no single origin from any lineage but a result of a conglomeration of different lineages from time to time. The phylogenetic analyses indicate a high degree of population admixture and a greater genetic proximity for the studied population groups when compared with other world populations.

  19. Cross-cultural differences in relationship- and group-based trust.

    Science.gov (United States)

    Yuki, Masaki; Maddux, William W; Brewer, Marilynn B; Takemura, Kosuke

    2005-01-01

    Two experiments explored differences in depersonalized trust (trust toward a relatively unknown target person) across cultures. Based on a recent theoretical framework that postulates predominantly different bases for group behaviors in Western cultures versus Eastern cultures, it was predicted that Americans would tend to trust people primarily based on whether they shared category memberships; however, trust for Japanese was expected to be based on the likelihood of sharing direct or indirect interpersonal links. Results supported these predictions. In both Study 1 (questionnaire study) and Study 2 (online money allocation game), Americans trusted ingroup members more than outgroup members; however, the existence of a potential indirect relationship link increased trust for outgroup members more for Japanese than for Americans. Implications for understanding group processes across cultures are discussed.

  20. Malaysian cultural differences in knowledge, attitudes and practices related to erectile dysfunction: focus group discussions.

    Science.gov (United States)

    Low, W Y; Wong, Y L; Zulkifli, S N; Tan, H M

    2002-12-01

    This qualitative study aimed to examine cultural differences in knowledge, attitudes and practices related to erectile dysfunction (ED) utilizing focus group discussion. Six focus groups consisting of 66 men, 45-70-y-old were conducted-two Malay groups (n=18), two Chinese groups (n=25) and two Indian groups (n=23). Participants were purposely recruited from the general public on a voluntary basis with informed consent. Transcripts were analyzed using qualitative data analysis software ATLASti. The Malay and Chinese traditional remedies for preventing or treating ED are commonly recognized among all races. Many have a negative perception of someone with ED. Malay and Chinese men tended to blame their wife for their problem and thought that the problem might lead to extra-marital affairs, unlike the Indian men who attributed their condition to fate. Malays would prefer traditional medicine for the problem. The Chinese felt they would be more comfortable with a male doctor whilst this is not so with the Malays or Indians. Almost all prefer the doctor to initiate discussion on sexual issues related to their medical condition. There is a need for doctors to consider cultural perspectives in a multicultural society as a lack of understanding of this often contributes to an inadequate consultation.

  1. Aggression and cortisol levels in three different group housing routines for lactating sows.

    Science.gov (United States)

    Thomsson, Ola; Bergqvist, Ann-Sofi; Sjunnesson, Ylva; Eliasson-Selling, Lena; Lundeheim, Nils; Magnusson, Ulf

    2015-02-18

    Lactating sows in Swedish organic piglet production are commonly group-housed with piglets in a multi-suckling pen within 14 days after farrowing. Nursing behaviour may be disturbed when lactating sows are moved to a new environment and mixed with other sows, as they spend more time fighting with other sows and exploring the new surroundings. This can disrupt the inhibitory effect of suckling on ovarian activity and increase the risk of lactational oestrus, making efficient reproductive management difficult. Therefore this study evaluated aggression and levels of the stress hormone cortisol in lactating sows group-housed together with their piglets at one (W1), two (W2) or three (W3) weeks post farrowing. There was no significant difference (P > 0.05) between the three management routines (W1, W2, W3) regarding number of attacks initiated or received in the mixed group. After mixing, W2 sows had a lower number of shoulder scratches (P sows. Among the W3 sows, there was a lower (P sows were group housed compared to when they were individually housed. The cortisol response, measured as variation in cortisol concentration in saliva, was also lower (P sows compared with W1 sows. For all management routines, sows already living in the new environment (resident sows) initiated more attacks (P sows entering the new environment (intruder sows). Overall, multiparous sows initiated more attacks and received fewer attacks than primiparous sows (P sows at three weeks post farrowing is less stressful than mixing and group housing sows at one week post farrowing. The results also indicate that parity and whether a sow is a resident or intruder in the group housing environment may have an effect on aggression levels when sows are group-housed.

  2. The relationship between personality traits and anxiety/depression levels in different drug abusers' groups

    OpenAIRE

    2013-01-01

    AIM: Since psychosocial characteristics of drug abuse involve mainly specific personality and emotional changes, it is very important to investigate characteristics of addictive personality in relationship with emotional state of the individual. Considering that, the objective of this study was to analyse the relationship between personality structure and emotional state of two different groups: heroin addicts and recreate drug abusers. METHODS: The total of 288 (219 males and 69 females; 191...

  3. Young and Older Emotional Faces: Are there Age-Group Differences in Expression Identification and Memory?

    OpenAIRE

    2009-01-01

    Studies finding that older compared to young adults are less able to identify facial expressions and have worse memory for negative than positive faces have used only young faces. Studies finding that both age groups are more accurate at recognizing faces of their own than other ages have used mostly neutral faces. Thus, age-differences in processing faces may not extend to older faces, and preferential memory for own-age faces may not extend to emotional faces. To investigate these possibili...

  4. Vibrotactile sense in patients with different upper limb disorders compared with a control group

    DEFF Research Database (Denmark)

    Laursen, Lise Hedegaard; Jepsen, Jørgen Riis; Sjøgaard, Gisela

    2006-01-01

    BACKGROUND: Upper limb disorders (ULDs) are common, and so are the difficulties with regard to their specific diagnoses. According to diagnostic consensus criteria, specific diagnoses include neuropathy and muscular- and connective-tissue disorders (MCDs). There is a need for valid objective...... diagnostic tools to reveal underlying mechanisms for specific diagnoses. OBJECTIVE: To investigate the possible differences in vibration perception threshold (VPT) and tolerance to suprathreshold stimulation (STS) between controls and specific diagnostic ULD patient groups with uni- and bilateral neuropathy...

  5. Ten Thousand Voices on Marine Climate Change in Europe: Different Perceptions among Demographic Groups and Nationalities

    KAUST Repository

    Buckley, Paul J.

    2017-07-11

    Over the past few decades, substantial funding has been directed toward improving scientific understanding and management of impacts of climate change in the marine environment. Following concerns that the key messages from these studies were not reaching the public, a comprehensive opinion poll of 10,000 European citizens in 10 countries was conducted to establish levels of awareness, concern, and trust among different demographic groups (by age, gender, proximity to the coast) and nationalities. Citizens exhibited varying levels of self-declared

  6. The Therapeutic role of Magnesium in different depressive syndromes of the male population comprising of different age groups

    Directory of Open Access Journals (Sweden)

    *N. Bano

    2011-12-01

    Full Text Available The basic and fundamental role of Mg as being the second most abundant intercellular cation is established in various studies. It is identified as a divalent metal cofactor in over 300 enzymatic reactions involving energy metabolism and protein and nucleic acid synthesis. The biological function is identified in neuromuscular excitability. Mg ion regulates calcium ion flow in neuronal channels, helping to regulate neuronal Nitric Oxide production1. Mg deficiency causes NMDA coupled Calcium channels to be biased towards opening, causing neuronal injury & neurological dysfunction, which may appear to humans as major depression. The present study confirms a reduction in the symptoms of depression found in the male population comprising of different age group by Mg treatment. CSF Mg has been found low in treatment resistant suicidal depression. Brain Mg is also low in TRD using phosphorous nuclear magnetic resonance Spectroscopy2. A 2009 randomized clinical trial shows that Mg therapy was an effective as TCAs in depressed diabetics. Increase in brain Mg enhances both short term synaptic facilitation and long term potentiation and improves learning and memory function3 The present study is based on findings that male subjects diagnosed as depressed showed a marked reduction in behavioral and somatic features of the disease after administration of Magnesium supplement. Physiological and somatic anxiety was also alleviated in a certain age group which displayed recovery from Insomnia and agitation. Suicidal tendency was also negative in all age groups. This study focuses on the behavioral and somatic responses pertaining to brain biochemical changes induced by Magnesium therapy.

  7. The Multilevel Mixed Intact Group Analysis: A Mixed Method to Seek, Detect, Describe, and Explain Differences Among Intact Groups

    Science.gov (United States)

    Schoonenboom, Judith

    2016-01-01

    Educational innovations often involve intact subgroups, such as school classes or university departments. In small-scale educational evaluation research, typically involving 1 to 20 subgroups, differences among these subgroups are often neglected. This article presents a mixed method from a qualitative perspective, in which differences among…

  8. Intimate relationships among adolescents in different social groups in northern Thailand.

    Science.gov (United States)

    Tangmunkongvorakul, Arunrat; Carmichael, Gordon; Banwell, Cathy; Seubsman, Sam-Ang; Sleigh, Adrian

    2010-11-01

    With the influence of modernization, there is evidence of increasing Thai adolescent sexual activity. The purpose of this study was to describe and compare the intimate relationships of adolescents in different social groups in northern Thailand, and to note the health implications of their behavior. Quantitative and qualitative data from more than 1,750 unmarried young people aged 17-20 years revealed that adolescents from different social and educational backgrounds had significantly different types of intimate relationships. In the Thai context, social class differences are mostly based on young people's educational backgrounds and their families' financial power. Perceptions of love and relationships were interpreted according to social strata and sex. Notably, less well-off young people were likely to engage in much riskier sexual relationships. The present study provides detailed and constructive information to help plan and improve sexual and reproductive health counselling, programs and services for young people in northern Thailand.

  9. Exposure To Harmful Workplace Practices Could Account For Inequality In Life Spans Across Different Demographic Groups.

    Science.gov (United States)

    Goh, Joel; Pfeffer, Jeffrey; Zenios, Stefanos

    2015-10-01

    The existence of important socioeconomic disparities in health and mortality is a well-established fact. Many pathways have been adduced to explain inequality in life spans. In this article we examine one factor that has been somewhat neglected: People with different levels of education get sorted into jobs with different degrees of exposure to workplace attributes that contribute to poor health. We used General Social Survey data to estimate differential exposures to workplace conditions, results from a meta-analysis that estimated the effect of workplace conditions on mortality, and a model that permitted us to estimate the overall effects of workplace practices on health. We conclude that 10-38 percent of the difference in life expectancy across demographic groups can be explained by the different job conditions their members experience.

  10. Sarcoidosis HLA class II genotyping distinguishes differences of clinical phenotype across ethnic groups

    Science.gov (United States)

    Sato, Hiroe; Woodhead, Felix A.; Ahmad, Tariq; Grutters, Jan C.; Spagnolo, Paolo; van den Bosch, Jules M.M.; Maier, Lisa A.; Newman, Lee S.; Nagai, Sonoko; Izumi, Takateru; Wells, Athol U.; du Bois, Roland M.; Welsh, Kenneth I.

    2010-01-01

    The HLA class II (DRB1 and DQB1) associations with sarcoidosis have been studied by several groups but often without consistent results. In this paper, we consider the hypothesis that observed inconsistencies relate to distinct, genetically encoded disease phenotypes which differ in prevalence between centres. We therefore typed HLA-DRB1 and DQB1 in 340 UK, 139 Dutch and 163 Japanese sarcoidosis patients and, respectively, 354, 218 and 168 healthy controls from these populations. We applied consistent phenotyping and genotyping and investigated associations between HLA class II alleles and distinct disease phenotypes within and between ethnic groups. DRB1*01 and DQB1*0501 are protective against all manifestations of sarcoidosis. Lung-predominant sarcoidosis is associated with DRB1*12 and *14. Löfgren's syndrome is a common sarcoidosis phenotype in the Dutch and is strongly associated with the DRB1*0301 allele. This phenotype is not seen among the Japanese in whom DRB1*0301 is absent. The same allele is protective for UK uveitis. Sarcoid uveitis is common in Japan. The DRB1*04–DQB1*0301 haplotype is a risk factor for this disease manifestation in Japanese and UK subjects but protective for sarcoidosis overall. We show that distinct sarcoidosis phenotypes have similar genetic associations across ethnic groups. The disease case mix differs between centres and may be explained by different ethnic allelic frequencies. PMID:20685690

  11. Group differences in physician responses to handheld presentation of clinical evidence: a verbal protocol analysis

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    Pavlovic Nada J

    2007-07-01

    Full Text Available Abstract Background To identify individual differences in physicians' needs for the presentation of evidence resources and preferences for mobile devices. Methods Within-groups analysis of responses to semi-structured interviews. Interviews consisted of using prototypes in response to task-based scenarios. The prototypes were implemented on two different form factors: a tablet style PC and a pocketPC. Participants were from three user groups: general internists, family physicians and medicine residents, and from two different settings: urban and semi-urban. Verbal protocol analysis, which consists of coding utterances, was conducted on the transcripts of the testing sessions. Statistical relationships were investigated between staff physicians' and residents' background variables, self-reported experiences with the interfaces, and verbal code frequencies. Results 47 physicians were recruited from general internal medicine, family practice clinics and a residency training program. The mean age of participants was 42.6 years. Physician specialty had a greater effect on device and information-presentation preferences than gender, age, setting or previous technical experience. Family physicians preferred the screen size of the tablet computer and were less concerned about its portability. Residents liked the screen size of the tablet, but preferred the portability of the pocketPC. Internists liked the portability of the pocketPC, but saw less advantage to the large screen of the tablet computer (F[2,44] = 4.94, p = .012. Conclusion Different types of physicians have different needs and preferences for evidence-based resources and handheld devices. This study shows how user testing can be incorporated into the process of design to inform group-based customization.

  12. Variation in Weed Seed Fate Fed to Different Holstein Cattle Groups.

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    Rahimi, Salman; Mashhadi, Hamid Rahimian; Banadaky, Mehdi Dehghan; Mesgaran, Mohsen Beheshtian

    2016-01-01

    Weed seeds may maintain their viability when passing through the digestive tract of cattle and can be therefore dispersed by animal movement or the application of manure. Whether different cattle types of the same species can cause differential weed seed fate is largely unknown to us particularly under non-grazed systems similar to Holstein-Friesian dairy farming. We investigated the effect on the seed survival of four weed species in the digestive tracts of four groups of Holstein cattle: lactating cows, feedlot male calves, dry cows and growing heifers. The weed species used were Cuscuta campestris, Polygonum aviculare, Rumex crispus and Sorghum halepense. Cattle excretion was sampled for recovery and viability of seeds at four 24 hourly intervals after seed intake. The highest seed recovery occurred two days after seed intake in all cattle groups. Averaged over weed species, dry and lactating cows had the lowest and highest seed recovery of 36.4% and 74.4% respectively. No significant differences were observed in seed recovery of the four weed species when their seeds were fed to dry cows. Based on a power model fitted to seed viability data, the estimated time to 50% viability loss after seed intake, over all cattle groups ranged from 65 h (R. crispus) to 76 h (P. aviculare). Recovered seeds from the dung of feedlot male calves showed the highest mortality among cattle groups. Significant correlation was found between seed viability and ruminal pH (r = 0.86; Pweed infestation caused by livestock should account for the variation amongst cattle groups in seed persistence. Our findings can be used as a guideline for evaluating the potential risk of the spread of weeds via the application of cattle manure.

  13. Evaluation and comparison of tooth size discrepancies among different malocclusion groups

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    Mujagić, A.

    2016-09-01

    Full Text Available Introduction: The compliance of proportions between the mesiodistal dimensions of the upper and the lower teeth is necessary for good intercuspidation. Given that a significant discrepancy in tooth size can prevent ideal occlusion at the end of orthodontic treatment, the absence of tooth size discrepancy is a significant factor for the realization of the ideal occlusion. Aim: Aim of this study was to determine whether there is a difference in the incidence of tooth size discrepancies among different skeletal malocclusion groups in the orthodontic patients. Material and methods: The sample comprised 300 pretreatment study casts (118 males and 182 females with fully erupted and complete permanent dentition except third molars, which were selected randomly from records of orthodontic patients. All subjects were divided in three groups, according to the Angle classification of malocclusion. The measurements were made on study models with digital calipers accurately to 0.01 mm. The Class was defined by using the Steiner analysis on lateral cephalograms. The subjects were divided into three groups depending on the value of the ANB angle. For every subject, the value of the angles SNA, SNB and ANB was measured. The reliability of measurements was examined by the Pearson’s correlation coefficient. To determine whether there were gender differences an independent sample t-test was performed. Results: There is no statistically significant differences in Bolton’s discrepancy by different gender, or at different classes. The average value of the anterior Bolton ratio was 78.16 and of the overall were 90.87. Values of the anterior and overall Bolton ratios are highest in patients with Class III. The highest average value of anterior discrepancy was in male subjects with III Class (-0.72, while the highest average value of overall discrepancy was in male subjects with II Class (0.65. Conclusion: The results of the study show that there are no

  14. Upper limb joint motion of two different user groups during manual wheelchair propulsion

    Science.gov (United States)

    Hwang, Seonhong; Kim, Seunghyeon; Son, Jongsang; Lee, Jinbok; Kim, Youngho

    2013-02-01

    Manual wheelchair users have a high risk of injury to the upper extremities. Recent studies have focused on kinematic and kinetic analyses of manual wheelchair propulsion in order to understand the physical demands on wheelchair users. The purpose of this study was to investigate upper limb joint motion by using a motion capture system and a dynamometer with two different groups of wheelchair users propelling their wheelchairs at different speeds under different load conditions. The variations in the contact time, release time, and linear velocity of the experienced group were all larger than they were in the novice group. The propulsion angles of the experienced users were larger than those of the novices under all conditions. The variances in the propulsion force (both radial and tangential) of the experienced users were larger than those of the novices. The shoulder joint moment had the largest variance with the conditions, followed by the wrist joint moment and the elbow joint moment. The variance of the maximum shoulder joint moment was over four times the variance of the maximum wrist joint moment and eight times the maximum elbow joint moment. The maximum joint moments increased significantly as the speed and load increased in both groups. Quick and significant manipulation ability based on environmental changes is considered an important factor in efficient propulsion. This efficiency was confirmed from the propulsion power results. Sophisticated strategies for efficient manual wheelchair propulsion could be understood by observation of the physical responses of each upper limb joint to changes in load and speed. We expect that the findings of this study will be utilized for designing a rehabilitation program to reduce injuries.

  15. Synchrotron-based XRD from rat bone of different age groups.

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    Rao, D V; Gigante, G E; Cesareo, R; Brunetti, A; Schiavon, N; Akatsuka, T; Yuasa, T; Takeda, T

    2017-05-01

    Synchrotron-based XRD spectra from rat bone of different age groups (w, 56 w and 78w), lumber vertebra at early stages of bone formation, Calcium hydroxyapatite (HAp) [Ca10(PO4)6(OH)2] bone fill with varying composition (60% and 70%) and bone cream (35-48%), has been acquired with 15keV synchrotron X-rays. Experiments were performed at Desy, Hamburg, Germany, utilizing the Resonant and Diffraction beamline (P9), with 15keV X-rays (λ=0.82666 A(0)). Diffraction data were quantitatively analyzed using the Rietveld refinement approach, which allowed us to characterize the structure of these samples in their early stages. Hydroxyapatite, received considerable attention in medical and materials sciences, since these materials are the hard tissues, such as bone and teeth. Higher bioactivity of these samples gained reasonable interest for biological application and for bone tissue repair in oral surgery and orthopedics. The results obtained from these samples, such as phase data, crystalline size of the phases, as well as the degree of crystallinity, confirm the apatite family crystallizing in a hexagonal system, space group P63/m with the lattice parameters of a=9.4328Å and c=6.8842Å (JCPDS card #09-0432). Synchrotron-based XRD patterns are relatively sharp and well resolved and can be attributed to the hexagonal crystal form of hydroxyapatite. All the samples were examined with scanning electron microscope at an accelerating voltage of 15kV. The presence of large globules of different sizes is observed, in small age groups of the rat bone (8w) and lumber vertebra (LV), as distinguished from, large age groups (56 and 78w) in all samples with different magnification, reflects an amorphous phase without significant traces of crystalline phases. Scanning electron microscopy (SEM) was used to characterize the morphology and crystalline properties of Hap, for all the samples, from 2 to 100μm resolution.

  16. PREVALENCE OF VITAMIN D DEFICIENCY IN DIFFERENT GROUPS OF CHRONIC RENAL FAILURE PATIENTS.

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    Bistra T. Galunska

    2015-09-01

    Full Text Available Purpose: To determine and compare the vitamin D status of different groups CKD patients on hemodialysis, peritoneal dialysis, or no renal replacement therapy and to evaluate the effect of vitamin D therapy. Patients and Methods: This pilot study enrolled 40 consecutive CKD patients (21 men, 19 women divided into three groups: 15 CKD patients in 1,2,3,4 stage of the disease without renal replacement therapy (RRT; 10CKD patients on hemodialysis (HD and 15 CKD patients on peritoneal dialysis (PD, ten of which were on vitamin D therapy. Vitamin D status was determined by serum 25-xydroxyvitamin D (25OHD. Results: Ninety percent of patients were in vitamin D deficiency/insufficiency; and only 4 patients (10.0% reached 25OHD levels above 75nmol/L. The median 25OHD level was 31.15nmol/L (interquartile range: 16.67-48.33nmol/L.Tendency of worse vitamin D status in women than in men was observed. Higher 25OHD levels were found in pre-dialysis patients (median 44.81nmol/L, 25%-75% percentile 16.24-52.21nmol/L and lower in HD (median 31.15nmol/L, 25%-75% percentile 13.04-64.45nmol/L and PD patients (median 33.38nmol/L, 25%-75% percentile 23.15-48.49nmol/L, but the difference did not reach statistical significance. Better vitamin D status was found in the PD group of patients receiving vitamin D preparations (p<0.05. Conclusions: 25OHD deficiency/insufficiency is prevalent in renal failure patients with or without renal replacement therapy. It seems that vitamin D therapy improves the vitamin D status of PD patients. Further larger studies are needed to clarify the effect of specific type vitamin D therapy on serum 25OHD levels and clinical outcome in different groups of CKD patients.

  17. Differences in social skills performance between institutionalized juvenile male offenders and a comparable group of boys without offence records.

    Science.gov (United States)

    Spence, S H

    1981-09-01

    Eighteen institutionalized young male offenders and 18 boys without criminal records, comparable in terms of age, academic performance and social background, were videotaped during a five-minute standardized interview with a previously unknown adult. The videotapes were then subjected to a behavioural analysis of 13 responses which had previously been suggested to be important social skill components. The tapes were also shown to six independent judges who rated each tape in terms of social skills performance, social anxiety, friendliness, and employability. The offender group was found to differ significantly from the non-offender group in terms of the level of eye-contact, head movements, amount spoken, fiddling movements, and gross body movements. The offender group was also rated in significantly less favourably terms on the scales of social skills performance, social anxiety, and employability, compared to the non-offender groups. No significant difference was found in terms of friendliness ratings. Correlation analyses between the specific behavioural measures and the subjective rating scales revealed statistically significant associations between six of the 13 behavioural measures and one or more of the subjective rating scales. The provides some indication of the type of responses important in determining the impression made by adolescent male in an interview situation.

  18. Human candidate polymorphisms in sympatric ethnic groups differing in malaria susceptibility in Mali.

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    Bakary Maiga

    Full Text Available Malaria still remains a major public health problem in Mali, although disease susceptibility varies between ethnic groups, particularly between the Fulani and Dogon. These two sympatric groups share similar socio-cultural factors and malaria transmission rates, but Fulani individuals tend to show significantly higher spleen enlargement scores, lower parasite prevalence, and seem less affected by the disease than their Dogon neighbours. We have used genetic polymorphisms from malaria-associated genes to investigate associations with various malaria metrics between the Fulanai and Dogon groups. Two cross sectional surveys (transmission season 2006, dry season 2007 were performed. Healthy volunteers from the both ethnic groups (n=939 were recruited in a rural setting. In each survey, clinical (spleen enlargement, axillary temperature, weight and parasitological data (malaria parasite densities and species were collected, as well as blood samples. One hundred and sixty six SNPs were genotyped and 5 immunoassays (AMA1, CSP, MSP1, MSP2, total IgE were performed on the DNA and serum samples respectively. The data confirm the reduced malaria susceptibility in the Fulani, with a higher level of the protective O-blood group, and increased circulating antibody levels to several malaria antigens (p<10(-15. We identified SNP allele frequency differences between the 2 ethnic groups in CD36, IL4, RTN3 and ADCY9. Moreover, polymorphisms in FCER1A, RAD50, TNF, SLC22A4, and IL13 genes were correlated with antibody production (p-value<0.003. Further work is required to understand the mechanisms underpinning these genetic factors.

  19. Human candidate polymorphisms in sympatric ethnic groups differing in malaria susceptibility in Mali.

    Science.gov (United States)

    Maiga, Bakary; Dolo, Amagana; Touré, Ousmane; Dara, Victor; Tapily, Amadou; Campino, Susana; Sepulveda, Nuno; Risley, Paul; Silva, Nilupa; Silva, Nipula; Corran, Patrick; Rockett, Kirk A; Kwiatkowski, Dominic; Clark, Taane G; Troye-Blomberg, Marita; Doumbo, Ogobara K

    2013-01-01

    Malaria still remains a major public health problem in Mali, although disease susceptibility varies between ethnic groups, particularly between the Fulani and Dogon. These two sympatric groups share similar socio-cultural factors and malaria transmission rates, but Fulani individuals tend to show significantly higher spleen enlargement scores, lower parasite prevalence, and seem less affected by the disease than their Dogon neighbours. We have used genetic polymorphisms from malaria-associated genes to investigate associations with various malaria metrics between the Fulanai and Dogon groups. Two cross sectional surveys (transmission season 2006, dry season 2007) were performed. Healthy volunteers from the both ethnic groups (n=939) were recruited in a rural setting. In each survey, clinical (spleen enlargement, axillary temperature, weight) and parasitological data (malaria parasite densities and species) were collected, as well as blood samples. One hundred and sixty six SNPs were genotyped and 5 immunoassays (AMA1, CSP, MSP1, MSP2, total IgE) were performed on the DNA and serum samples respectively. The data confirm the reduced malaria susceptibility in the Fulani, with a higher level of the protective O-blood group, and increased circulating antibody levels to several malaria antigens (p<10(-15)). We identified SNP allele frequency differences between the 2 ethnic groups in CD36, IL4, RTN3 and ADCY9. Moreover, polymorphisms in FCER1A, RAD50, TNF, SLC22A4, and IL13 genes were correlated with antibody production (p-value<0.003). Further work is required to understand the mechanisms underpinning these genetic factors.

  20. Comparison of Masking Level Difference in Patients with Multiple Sclerosis and Healthy Control Group

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    Soghrat Faghihzadeh

    2012-03-01

    Full Text Available Background and Aim: Multiple sclerosis (MS is a neurological disorder that involves central nervous system. Studies have showed that multiple sclerosis affects behavioral central auditory tests, such as masking release or masking level difference (MLD. The purpose of this study is to compare the masking level difference between multiple sclerosis patients and normal subjects.Methods: This cross sectional and non-interventional study was conducted on 32 multiple sclerosis patients aged between 20-50 years and 32 controls matched for age and gender in Faculty of Rehabilitation, Tehran University of Medical Sciences. masking level difference test was performed on each subject.Results: The mean masking level difference in the two groups was significantly different (p<0.01 however, gender did not prove to play a role in this difference.Conclusion: As part of the multiple sclerosis diagnosis panel, masking level difference test is an efficient modality for evaluation of hearing impairment and monitoring of rehabilitation progress.

  1. Stoichiometric differences in DNA molecules containing the atpA gene suggest mechanisms for the generation of mitochondrial genome diversity in maize.

    Science.gov (United States)

    Small, I D; Isaac, P G; Leaver, C J

    1987-04-01

    Four genomic arrangements of the maize mitochondrial atpA gene (encoding the alpha subunit of the F(1) ATPase), have been characterized. Most N (fertile) and S (male-sterile) cytoplasms contain two atpA arrangements of equal abundance. Prolonged exposure of blots of maize mitochondrial DNA probed with atpA-specific sequences show that cytoplasms previously reported to lack one of the atpA arrangements do contain the second arrangement but at low levels. Similarly, restriction fragments containing the atpA gene previously thought unique to male-sterile S and T cytoplasms are present in low abundance in fertile cytoplasms. These observations suggest that fertile and male-sterile cytoplasms of maize may be more closely related than previously thought, and suggest possible mechanisms to explain the observed mitochondrial genome diversity.

  2. Infestation by Rhipicephalus (Boophilus microplus in heifers from different genetics groups

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    Adilson Marini

    2010-01-01

    Full Text Available An assessment of the infestation of ticks Rhipicephalus (Boophilus microplus in 59 heifers of three genetic groups was run: Nellore, Guzerá and ½ Angus x ½ Nellore, belonging to the roster APTA Regional Andradina / SP. Every 28 days held the count of ticks, where the left side of the animal, with evaluation of only engorged females with more than 4.5 mm in the period from June 2007 to May 2008. The genetic group (P 0.05. The count of ticks was higher in the rainy season (4.32 ± 5.20 in comparison with the dry season (3.74 ± 5.54. Despite the higher counts of ticks during the experimental period, in heifers ½ Angus x ½ Nellore, this genetic group obtained the highest average daily weight gain (0.57 kg/day. Heifers and bulls Nellore and Guzerá were not statistically different in relation to daily weight gain, with averages of 0.37 and 0.40kg/day, respectively. ½ Angus heifers genetic group cattle have a higher infestation by ticks.

  3. Group-based differences in anti-aging bias among medical students.

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    Ruiz, Jorge G; Andrade, Allen D; Anam, Ramanakumar; Taldone, Sabrina; Karanam, Chandana; Hogue, Christie; Mintzer, Michael J

    2015-01-01

    Medical students (MS) may develop ageist attitudes early in their training that may predict their future avoidance of caring for the elderly. This study sought to determine MS' patterns of explicit and implicit anti-aging bias, intent to practice with older people and using the quad model, the role of gender, race, and motivation-based differences. One hundred and three MS completed an online survey that included explicit and implicit measures. Explicit measures revealed a moderately positive perception of older people. Female medical students and those high in internal motivation showed lower anti-aging bias, and both were more likely to intend to practice with older people. Although the implicit measure revealed more negativity toward the elderly than the explicit measures, there were no group differences. However, using the quad model the authors identified gender, race, and motivation-based differences in controlled and automatic processes involved in anti-aging bias.

  4. Mapping biodiversity value worldwide: combining higher-taxon richness from different groups

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    Williams, P. H.; Gaston, K. J.; Humphries, C. J.

    1997-01-01

    Maps of large-scale biodiversity are urgently needed to guide conservation, and yet complete enumeration of organisms is impractical at present. One indirect approach is to measure richness at higher taxonomic ranks, such as families. The difficulty is how to combine information from different groups on numbers of higher taxa, when these taxa may in effect have been defined in different ways, particularly for more distantly related major groups. In this paper, the regional family richness of terrestrial and freshwater seed plants, amphibians, reptiles and mammals is mapped worldwide by combining: (i) absolute family richness; (ii) proportional family richness; and (iii) proportional family richness weighted for the total species richness in each major group. The assumptions of the three methods and their effects on the results are discussed, although for these data the broad pattern is surprisingly robust with respect to the method of combination. Scores from each of the methods of combining families are used to rank the top five richness hotspots and complementary areas, and hotspots of endemism are mapped by unweighted combination of range-size rarity scores.

  5. Statistically significant faunal differences among Middle Ordovician age, Chickamauga Group bryozoan bioherms, central Alabama

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    Crow, C.J.

    1985-01-01

    Middle Ordovician age Chickamauga Group carbonates crop out along the Birmingham and Murphrees Valley anticlines in central Alabama. The macrofossil contents on exposed surfaces of seven bioherms have been counted to determine their various paleontologic characteristics. Twelve groups of organisms are present in these bioherms. Dominant organisms include bryozoans, algae, brachiopods, sponges, pelmatozoans, stromatoporoids and corals. Minor accessory fauna include predators, scavengers and grazers such as gastropods, ostracods, trilobites, cephalopods and pelecypods. Vertical and horizontal niche zonation has been detected for some of the bioherm dwelling fauna. No one bioherm of those studied exhibits all 12 groups of organisms; rather, individual bioherms display various subsets of the total diversity. Statistical treatment (G-test) of the diversity data indicates a lack of statistical homogeneity of the bioherms, both within and between localities. Between-locality population heterogeneity can be ascribed to differences in biologic responses to such gross environmental factors as water depth and clarity, and energy levels. At any one locality, gross aspects of the paleoenvironments are assumed to have been more uniform. Significant differences among bioherms at any one locality may have resulted from patchy distribution of species populations, differential preservation and other factors.

  6. Capturing Age-group Differences and Developmental Change with the BASC Parent Rating Scales.

    Science.gov (United States)

    Barbot, Baptiste; Hein, Sascha; Luthar, Suniya S; Grigorenko, Elena L

    2014-07-01

    Estimation of age-group differences and intra-individual change across distinct developmental periods is often challenged by the use of age-appropriate (but non-parallel) measures. We present a short version of the Behavior Assessment System (Reynolds & Kamphaus, 1998), Parent Rating Scales for Children (PRS-C) and Adolescents (PRS-A), which uses only their common-items to derive estimates of the initial constructs optimized for developmental studies. Measurement invariance of a three-factor model (Externalizing, Internalizing, Adaptive Skills) was tested across age-groups (161 mothers using PRS-C; 200 mothers using PRS-A) and over time (115 mothers using PRS-C at baseline and PRS-A five years later) with the original versus short PRS. Results indicated that the short PRS holds a sufficient level of invariance for a robust estimation of age-group differences and intra-individual change, as compared to the original PRS, which held only weak invariance leading to flawed developmental inferences. Importance of test-content parallelism for developmental studies is discussed.

  7. Curve of Spee and its relationship to vertical eruption of teeth among different malocclusion groups.

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    Veli, Ilknur; Ozturk, Mehmet Ali; Uysal, Tancan

    2015-03-01

    Our objectives were to assess the depth of the curve of Spee (COS) in different malocclusion groups, to relate this to the eruption of anterior or posterior teeth quantitatively, and to determine whether the depth of the COS is affected by the vertical eruption of anterior or posterior teeth. Two hundred conventional lateral cephalograms and 3-dimensional models of untreated patients (70 boys, mean age: 16.4 ± 1.4 years; 130 young women, mean age: 18.1 ± 1.8 years) were included and assigned to 4 malocclusion groups as Class I, Class II Division 1, Class II Division 2, and Class III. The depth of the COS, overjet, and overbite were measured on 3-dimensional models. The perpendicular distance between the incisal tip of the mandibular central incisor (L1-MP), the deepest point of the COS (S-MP), and the distobuccal cusp tip of the mandibular second molar (L7-MP) to the mandibular plane were calculated and proportioned with each other. The Pearson correlation coefficient was calculated, and multiple linear regression analysis was carried out. Also, multivariate analysis of variance was performed at the P Class II Division 2 > Class I > Class III malocclusion groups. Statistically significant positive correlations were found between the depth of the COS and L1-MP/S-MP (r = 0.541) and L7-MP/S-MP (r = 0.269) in the Class I and Class III subjects, and between the depth of the COS and overjet (r = 0.483) and L7-MP/S-MP (r = 0.289) in the Class II Division 1 subjects. All variables except overjet had positive correlations with the depth of the COS in Class II Division 2 subjects. The multivariate analysis of variance showed statistically significant differences in overjet, overbite, L1-MP/S-MP, L7-MP/S-MP, and the depth of the COS (P overjet differed, vertical eruption of the anterior teeth did not differ among the different malocclusion groups and had a significant contribution to the depth of the COS in subjects with Class I and Class III malocclusions. Copyright

  8. Historical, theoretical methodological foundations of recreational activity of different population groups

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    Olena Andreeva

    2015-04-01

    Full Text Available Purpose: to justify and develop historical, theoretical and methodological foundations of recreational activity to meet the recreational needs of different population groups. Material and Methods: analysis and systematization of the special scientific and methodological literature and informational Internet resources; comparative method, historical analysis; systemic approach. The study involved school and college students and adults, in total of 1150 persons. Results: historical backgrounds of formation and development of recreation in the world and Ukraine are analyzed. Theoretical generalization of certain concepts of motivation in the area of physical recreation is provided, as well as theoretical and organizational principles of leisure and recreation in foreign countries are discussed. Conclusions: historical backgrounds of development of knowledge about recreation are identified and conceptual approaches to development of the theoretical and methodological foundations of recreational activities of various population groups are determined.

  9. Ethnic and gender differences in the association between discrimination and depressive symptoms among five immigrant groups.

    Science.gov (United States)

    Kim, Il-Ho; Noh, Samuel

    2014-12-01

    This study examines ethnic and gender differences in exposure to discrimination and its association with depressive symptoms among five immigrant groups. Data were derived from a cross-sectional survey of 900 adult immigrants (50.8% men, 49.2% women) sampled from five ethnic immigrant communities in Toronto between April and September 2001. Men reported higher levels of discrimination than women. Ethiopians had the highest perception of discrimination followed by Korean, Iranian, Vietnamese, and Irish immigrants. With regard to discrimination-related depressive symptoms, Iranian and Korean men showed a greater risk than their Irish counterparts. Among women, Vietnamese and Irish seemed to be more vulnerable to discrimination than other ethnic groups. Despite experiencing the highest level of discrimination, Ethiopian men and women showed no association between discrimination and depressive symptoms. The exposure and psychological response to discrimination vary significantly across ethnicities and gender.

  10. INVESTIGATION OF BRAND NAME-COUNTRY OF ORIGIN PREFERENCE IN FOUR DIFFERENT PRODUCT GROUPS WITH RESPECT TO CONSPICUOUS CONSUMPTION TENDENCY

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    Volkan Doğan

    2013-10-01

    Full Text Available The aim of this study is to examine different preferences for brand name–country of origin shaped in line with levels of conspicuous consumption tendency and to determine Turkish consumers’ preferences for brand name–country of origin combinations in different product groups. The study was conducted in Eskisehir (Turkey with a sample of 413 people chosen through convenience sampling. The study data were collected with a questionnaire and face-face-to interviews. The participants’ preferences for brand name-country of origin combinations were determined separately based on four different product groups(hedonic, utilitarian, durable and non-durable. The study showed that, for all the four product groups, the participants preferred the products with a Turkish brand name and Turkey as the country of origin most, followed by the products with a French brand name and France as the country of origin. This finding suggests that, with respect to the four product groups in the study, Turkish consumers preferred domestic products over foreign products. Also, the participants who preferred French brand name-France as the country of origin for the hedonic product, French brand name-Turkey as the country of origin for the utilitarian product, French brand name-Turkey as the country of origin for the durable product and French brand name-France as the country of origin for the non-durable product were found to have highest tendency of conspicuous consumption in the corresponding product groups. In other words, as the level of conspicuous consumption increased, the participants tended to prefer French brand name-France as the country of origin for the hedonic product, French brand name-Turkey as the country of origin for the utilitarian product, French brand name-Turkey as the country of origin for the durable product and French brand name-France as the country of origin for the non-durable product.

  11. Generalization of Muscle Strength Capacities as Assessed From Different Variables, Tests, and Muscle Groups.

    Science.gov (United States)

    Cuk, Ivan; Prebeg, Goran; Sreckovic, Sreten; Mirkov, Dragan M; Jaric, Slobodan

    2017-02-01

    Cuk, I, Prebeg, G, Sreckovic, S, Mirkov, DM, and Jaric, S. Generalization of muscle strength capacities as assessed from different variables, tests, and muscle groups. J Strength Cond Res 31(2): 305-312, 2017-The muscle strength capacities to exert force under various movement conditions have been indiscriminately assessed from various strength tests and variables applied on different muscles. We tested the hypotheses that the distinctive strength capacities would be revealed (H1) through different strength tests, and (H2) through different strength variables. Alternatively, (H3) all strength variables independent of the selected test could depict the same strength capacity of the tested muscle. Sixty subjects performed both the standard strength test and the test of alternating contractions of 6 pairs of antagonistic muscles acting in different leg and arm joints. The dependent variables obtained from each test and muscle were the maximum isometric force and the rate of force development. A confirmatory principle component analysis set to 2 factors explained 31.9% of the total variance. The factor loadings discerned between the tested arm and leg muscles, but not between the strength tests and variables. An exploratory analysis applied on the same data revealed 6 factors that explained 60.1% of the total variance. Again, the individual factors were mainly loaded by different tests and variables obtained from the same pair of antagonistic muscles. Therefore, a comprehensive assessment of the muscle strength capacity of the tested individual should be based on a single strength test and variable obtained from a number of different muscles, than on a single muscle tested through different tests and variables. The selected muscles should act in different limbs and joints, while the maximum isometric force should be the variable of choice.

  12. Water content differences have stronger effects than plant functional groups on soil bacteria in a steppe ecosystem.

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    Ximei Zhang

    Full Text Available Many investigations across natural and artificial plant diversity gradients have reported that both soil physicochemical factors and plant community composition affect soil microbial communities. To test the effect of plant diversity loss on soil bacterial communities, we conducted a five-year plant functional group removal experiment in a steppe ecosystem in Inner Mongolia (China. We found that the number and composition type of plant functional groups had no effect on bacterial diversity and community composition, or on the relative abundance of major taxa. In contrast, bacterial community patterns were significantly structured by soil water content differences among plots. Our results support researches that suggest that water availability is the key factor structuring soil bacterial communities in this semi-arid ecosystem.

  13. Retrospective study of cancer types in different ethnic groups and genders at Karachi.

    Science.gov (United States)

    Khaliq, Sheikh Abdul; Naqvi, Syed Baqir; Fatima, Anab

    2013-12-01

    Retrospective study of Cancer types in different ethnic groups & genders determines the pattern of cancers in different ethnic groups & genders during the last eight years reported in Oncology wards of hospitals of Karachi, Pakistan. Every single one male & female case with histologically and cytologically established cancer was enrolled from January 2003 to December 2010. Data for all patients were collected retrospectively by patient's file & charts, which represents the population of Karachi, Interior Sindh & Balochistan. 5134 patients (Male = 2432 / Female = 2702) investigated for their diagnosis of cancer type, ethnicity, age & gender. Classification of malignancy was done according to the International Classification of Disease coding system by W.H.O (ICD-10). The statistical analysis was performed for mean, standard error & proportions for ethnic groups & genders. Proportionately 47.37% males and among which major ethnic groups 17% Sindhi, 17% Immigrant, 4% Baloch, 3% Pukhtoon, ≈ 4% Punjabi, 1% Siraiki, 2% Minorities and 52.62% females, in which 16% Sindhi, 21% Immigrant, 4% Baloch 3% Pukhtoon, 5% Punjabi, 1% Siraiki, 3% Minorities. Mean age of males = 45.75 years, SE ± 0.227 and for females = 44.07, SE ± 0.183. The three most occurring tumors in all cancers of male were found Head & Neck, Adenoma/Carcinoma of Glands & Body cavity membranes, GIT, and females Breast, Head & Neck, Adenoma/Carcinoma of Glands & Body cavity membranes, GIT. The analysis of data indicates Head & Neck is most common cancer among male, in the similar way Breast cancer is the most common malignancy among female.

  14. Comparison of different sampling techniques and of different culture methods for detection of group B streptococcus carriage in pregnant women.

    Science.gov (United States)

    El Aila, Nabil A; Tency, Inge; Claeys, Geert; Saerens, Bart; Cools, Piet; Verstraelen, Hans; Temmerman, Marleen; Verhelst, Rita; Vaneechoutte, Mario

    2010-09-29

    Streptococcus agalactiae (group B streptococcus; GBS) is a significant cause of perinatal and neonatal infections worldwide. To detect GBS colonization in pregnant women, the CDC recommends isolation of the bacterium from vaginal and anorectal swab samples by growth in a selective enrichment medium, such as Lim broth (Todd-Hewitt broth supplemented with selective antibiotics), followed by subculture on sheep blood agar. However, this procedure may require 48 h to complete. We compared different sampling and culture techniques for the detection of GBS. A total of 300 swabs was taken from 100 pregnant women at 35-37 weeks of gestation. For each subject, one rectovaginal, one vaginal and one rectal ESwab were collected. Plating onto Columbia CNA agar (CNA), group B streptococcus differential agar (GBSDA) (Granada Medium) and chromID Strepto B agar (CA), with and without Lim broth enrichment, were compared. The isolates were confirmed as S. agalactiae using the CAMP test on blood agar and by molecular identification with tDNA-PCR or by 16S rRNA gene sequence determination. The overall GBS colonization rate was 22%. GBS positivity for rectovaginal sampling (100%) was significantly higher than detection on the basis of vaginal sampling (50%), but not significantly higher than for rectal sampling (82%). Direct plating of the rectovaginal swab on CNA, GBSDA and CA resulted in detection of 59, 91 and 95% of the carriers, respectively, whereas subculturing of Lim broth yielded 77, 95 and 100% positivity, respectively. Lim broth enrichment enabled the detection of only one additional GBS positive subject. There was no significant difference between GBSDA and CA, whereas both were more sensitive than CNA. Direct culture onto GBSDA or CA (91 and 95%) detected more carriers than Lim broth enrichment and subculture onto CNA (77%). One false negative isolate was observed on GBSDA, and three false positives on CA. In conclusion, rectovaginal sampling increased the number GBS

  15. Hypnosis, suggestion, and suggestibility: an integrative model.

    Science.gov (United States)

    Lynn, Steven Jay; Laurence, Jean-Roch; Kirsch, Irving

    2015-01-01

    This article elucidates an integrative model of hypnosis that integrates social, cultural, cognitive, and neurophysiological variables at play both in and out of hypnosis and considers their dynamic interaction as determinants of the multifaceted experience of hypnosis. The roles of these variables are examined in the induction and suggestion stages of hypnosis, including how they are related to the experience of involuntariness, one of the hallmarks of hypnosis. It is suggested that studies of the modification of hypnotic suggestibility; cognitive flexibility; response sets and expectancies; the default-mode network; and the search for the neurophysiological correlates of hypnosis, more broadly, in conjunction with research on social psychological variables, hold much promise to further understanding of hypnosis.

  16. The Perception of Critical Success Factors for PPP Projects in Different Stakeholder Groups

    Directory of Open Access Journals (Sweden)

    Joanna Węgrzyn

    2016-06-01

    Full Text Available Objective:  The main goal of the research is to enhance understanding which factors are perceived as critical for the success of public-private partnerships (PPPs by different stakeholder groups on different stages of the project life cycle. Research Design & Methods:  The paper builds on a larger research study looking at the development of the best practice framework for PPPs. The research is based on both a literature review and empirical studies. To examinethe perception of critical success factors (CSFs a questionnaire was conducted within different stakeholder groups for PPPs in Poland. Findings:  The article concentrates on one of the two dimensions ofa PPP project success which is the idea of critical success factors. The research reveals that public and private parties do not share common perception of the PPPsuccess. In general, the private sector assigns lower values to the CSFs analysed from the whole life perspective of a PPP project. Implications & Recommendations: The research indicates that the interpretation of a PPP project success depends of the stakeholders' role  in the project. Future research might try to integrate a wider range of stakeholdersengaged in PPPs such as financial institutions or a final user of the services provided under a PPP project. Contribution & Value Added: The results of the study provides helpful information to identify areas that stakeholders should pay a specialattention to in order to achieve the success of a PPP project.

  17. Sport Tourism Centres from Top Athletes’ Perspective: Differences among Sport Groups

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    Polanec Anze

    2014-09-01

    Full Text Available Background: Sport tourism plays an important role in the tourism industry and consequently in the economy. Sport tourism centres as providers of sport services need to be familiar with the basic needs of their customers and tailor their services accordingly. Objectives: The aim of the paper is to determine the models for customizing sport tourism services to address the needs specific for an individual sport. Methods/Approach: A questionnaire has been created and sent electronically or physically to top athletes from Slovenia, Central and Eastern Europe. Respondents were mainly from Slovenia and mostly representatives of national sports federations. The Mann Whitney and the Kruskall-Wallis tests were applied in order to test differences among sport groups. Results: The conducted Mann-Whitney non-parametric tests show that representatives of different sport groups have different perspectives on sport tourism services. Conclusions: The results of the study can be used by sport tourism centres in the process of tailoring their services, planning marketing activities or developing strategic projects.

  18. Identification of a novel PNMA-MS1 gene in marsupials suggests the LTR retrotransposon-derived PNMA genes evolved differently in marsupials and eutherians.

    Science.gov (United States)

    Iwasaki, Sawa; Suzuki, Shunsuke; Pelekanos, Matthew; Clark, Helen; Ono, Ryuichi; Shaw, Geoff; Renfree, Marilyn B; Kaneko-Ishino, Tomoko; Ishino, Fumitoshi

    2013-10-01

    Two major gene families derived from Ty3/Gypsy long terminal repeat (LTR) retrotransposons were recently identified in mammals. The sushi-ichi retrotransposon homologue (SIRH) family comprises 12 genes: 11 in eutherians including Peg10 and Peg11/Rtl1 that have essential roles in the eutherian placenta and 1 that is marsupial specific. Fifteen and 12 genes were reported in the second gene family, para-neoplastic antigen MA (PNMA), in humans and mice, respectively, although their biological functions and evolutionary history remain largely unknown. Here, we identified two novel candidate PNMA genes, PNMA-MS1 and -MS2 in marsupials. Like all eutherian-specific PNMA genes, they exhibit the highest homology to a Gypsy12_DR (DR, Danio rerio) Gag protein. PNMA-MS1 is conserved in both Australian and South American marsupial species, the tammar wallaby and grey short-tailed opossum. However, no PNMA-MS1 orthologue was found in eutherians, monotremes or non-mammalian vertebrates. PNMA-MS1 was expressed in the ovary, mammary gland and brain during development and growth in the tammar, suggesting that PNMA-MS1 may have acquired a marsupial-specific function. However, PNMA-MS2 seems to be a pseudogene. The absence of marsupial orthologues of eutherian PNMA genes suggests that the retrotransposition events of the Gypsy12_DR-related retrotransposons that gave rise to the PNMA family occurred after the divergence of marsupials and eutherians.

  19. Determination of equivalent breast phantoms for different age groups of Taiwanese women: An experimental approach

    Energy Technology Data Exchange (ETDEWEB)

    Dong, Shang-Lung; Chu, Tieh-Chi; Lin, Yung-Chien; Lan, Gong-Yau; Yeh, Yu-Hsiu; Chen, Sharon; Chuang, Keh-Shih [Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101 Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan (China); Department of Radiology, Cheng Hsin General Hospital, 45 Cheng Hsin Street, Pai-Tou District, Taipei 11220, Taiwan (China); Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung 80708, Taiwan (China); Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101 Section 2, Kuang-Fu Road, Hsinchu 30013, Taiwan (China)

    2011-07-15

    Purpose: Polymethylmethacrylate (PMMA) slab is one of the mostly used phantoms for studying breast dosimetry in mammography. The purpose of this study was to evaluate the equivalence between exposure factors acquired from PMMA slabs and patient cases of different age groups of Taiwanese women in mammography. Methods: This study included 3910 craniocaudal screen/film mammograms on Taiwanese women acquired on one mammographic unit. The tube loading, compressed breast thickness (CBT), compression force, tube voltage, and target/filter combination for each mammogram were collected for all patients. The glandularity and the equivalent thickness of PMMA were determined for each breast using the exposure factors of the breast in combination with experimental measurements from breast-tissue-equivalent attenuation slabs. Equivalent thicknesses of PMMA to the breasts of Taiwanese women were then estimated. Results: The average {+-} standard deviation CBT and breast glandularity in this study were 4.2 {+-} 1.0 cm and 54% {+-} 23%, respectively. The average equivalent PMMA thickness was 4.0 {+-} 0.7 cm. PMMA slabs producing equivalent exposure factors as in the breasts of Taiwanese women were determined for the age groups 30-49 yr and 50-69 yr. For the 4-cm PMMA slab, the CBT and glandularity values of the equivalent breast were 4.1 cm and 65%, respectively, for the age group 30-49 yr and 4.4 cm and 44%, respectively, for the age group 50-69 yr. Conclusions: The average thickness of PMMA slabs producing the same exposure factors as observed in a large group of Taiwanese women is less than that reported for American women. The results from this study can provide useful information for determining a suitable thickness of PMMA for mammographic dose survey in Taiwan. The equivalence of PMMA slabs and the breasts of Taiwanese women is provided to allow average glandular dose assessment in clinical practice.

  20. São paulo judo team: study of competitive behavior tendency between athlets of differents groups

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    Helio Serassuelo Junior

    2006-12-01

    Full Text Available The main purpose of this research was to identify the competitive behavior tendency of Judo players according to personal tendencies of competing, winning and setting goals. The samples were separated by circumstantially being part (n=15 or not (n=37 of São Paulo State Team, in two different groups, A and B specifi cally, from different social background and between 14 and 21 years old. The evaluation tools were: Evaluation System ACS – 2 to collect information about competitive tendency; and a second one to obtain Sportive and Personal information about age, practice time and performance level. The Spearman Coeffi cient was used to analyze the intra-group relations between qualitative variables (tendencies of winning, competing and setting goals, and quantitative variables (age, practice time, performance level. The Q-Square was used to analyze the qualitative variables between groups and the test t for the quantitative variables. The results showed that there are signifi cant differences in the variables involved in this study between groups A and B, except for competing tendencies. In conclusion, no differences had been found between qualitative and quantitative variables, in the intra-group analyses but in inter-groups analyses there are signifi cant differences that showed the athletes with more age, practice time and performance level obtain best scores for the competitive tendencies analyzed, these elements can indicate possibilities to reach best results in sport competitions. The Evaluation System ACS – 2 was shown as a good and effi cient model to identify the different competitive behavior tendencies employed by male Judo players. RESUMO O presente estudo teve como objetivo principal identifi car as tendências de comportamento competitivo de atletas masculinos de Judô, em relação às suas tendências pessoais em vencer, competir e estabelecer metas. Os dados foram coletados, utilizando o Sistema de Avaliação ACS – 2 e o

  1. Statistical group differences in anatomical shape analysis using Hotelling T2 metric

    Science.gov (United States)

    Styner, Martin; Oguz, Ipek; Xu, Shun; Pantazis, Dimitrios; Gerig, Guido

    2007-03-01

    Shape analysis has become of increasing interest to the neuroimaging community due to its potential to precisely locate morphological changes between healthy and pathological structures. This manuscript presents a comprehensive set of tools for the computation of 3D structural statistical shape analysis. It has been applied in several studies on brain morphometry, but can potentially be employed in other 3D shape problems. Its main limitations is the necessity of spherical topology. The input of the proposed shape analysis is a set of binary segmentation of a single brain structure, such as the hippocampus or caudate. These segmentations are converted into a corresponding spherical harmonic description (SPHARM), which is then sampled into a triangulated surfaces (SPHARM-PDM). After alignment, differences between groups of surfaces are computed using the Hotelling T2 two sample metric. Statistical p-values, both raw and corrected for multiple comparisons, result in significance maps. Additional visualization of the group tests are provided via mean difference magnitude and vector maps, as well as maps of the group covariance information. The correction for multiple comparisons is performed via two separate methods that each have a distinct view of the problem. The first one aims to control the family-wise error rate (FWER) or false-positives via the extrema histogram of non-parametric permutations. The second method controls the false discovery rate and results in a less conservative estimate of the false-negatives. Prior versions of this shape analysis framework have been applied already to clinical studies on hippocampus and lateral ventricle shape in adult schizophrenics. The novelty of this submission is the use of the Hotelling T2 two-sample group difference metric for the computation of a template free statistical shape analysis. Template free group testing allowed this framework to become independent of any template choice, as well as it improved the

  2. Dominant negative phenotype of Bacillus thuringiensis Cry1Ab, Cry11Aa and Cry4Ba mutants suggest hetero-oligomer formation among different Cry toxins.

    NARCIS (Netherlands)

    Carmona, D.; Rodriguez-Almazan, C.; Munoz-Garay, C.; Portugal, L.; Perez, C.; Maagd, de R.A.; Bakker, P.; Soberon, M.; Bravo, A.

    2011-01-01

    Background - Bacillus thuringiensis Cry toxins are used worldwide in the control of different insect pests important in agriculture or in human health. The Cry proteins are pore-forming toxins that affect the midgut cell of target insects. It was shown that non-toxic Cry1Ab helix a-4 mutants had a d

  3. Phylogenetic Analysis of Human Parvovirus B19 Sequences from Eleven Different Countries Confirms the Predominance of Genotype 1 and Suggests the Spread of Genotype 3b▿

    Science.gov (United States)

    Hübschen, Judith M.; Mihneva, Zefira; Mentis, Andreas F.; Schneider, François; Aboudy, Yair; Grossman, Zehava; Rudich, Hagit; Kasymbekova, Kalia; Sarv, Inna; Nedeljkovic, Jasminka; Tahita, Marc C.; Tarnagda, Zekiba; Ouedraogo, Jean-Bosco; Gerasimova, A. G.; Moskaleva, T. N.; Tikhonova, Nina T.; Chitadze, Nazibrola; Forbi, J. C.; Faneye, Adedayo O.; Otegbayo, Jesse A.; Charpentier, Emilie; Muller, Claude P.

    2009-01-01

    Phylogenetic analysis of 166 human parvovirus B19 sequences from 11 different countries attributed 91.57% to genotype 1, 5.42% to genotype 3b, and 3.01% to genotype 3a. Very similar viruses of genotype 1 circulated widely in Europe and Israel. Genotype 3b seems to show an increasing spread outside of Africa. PMID:19741071

  4. Case Finding and Medical Treatment of Type 2 Diabetes among Different Ethnic Minority Groups: The HELIUS Study

    Directory of Open Access Journals (Sweden)

    Marieke B. Snijder

    2017-01-01

    Full Text Available Aims. Prevention of diabetes complications depends on the level of case finding and successful treatment of diabetes, which may differ between ethnicities. Therefore, we studied the prevalence by age, awareness, treatment, and control of type 2 diabetes, among a multiethnic population. Methods. We included 4,541 Dutch, 3,032 South-Asian Surinamese, 4,109 African Surinamese, 2,323 Ghanaian, 3,591 Turkish, and 3,887 Moroccan participants (aged 18–70 y from the HELIUS study. The prevalence of diabetes was analysed by sex, ethnicity, and 10-year age groups. Ethnic differences in the prevalence, awareness, treatment, and control of diabetes were studied by logistic regression. Results. From the age of 31–40 years and older, the prevalence of diabetes was 3 to 12 times higher among ethnic minority groups than that among the Dutch host population. Awareness and medical treatment of diabetes were 2 to 5 times higher among ethnic minorities than that among Dutch. Among those medically treated, only 37–53% had HbA1c levels on target (≤7.0%; only Dutch men had HbA1c levels on target more often (67%. Conclusions. Our results suggest that the age limit for case finding among ethnic minority groups should be lower than that for the general population. Importantly, despite higher awareness and treatment among ethnic minorities, glycemic control was low, suggesting a need for increased efforts to improve the effectiveness of treatment in these groups.

  5. Fusing multiple neuroimaging modalities to assess group differences in perception-action coupling.

    Science.gov (United States)

    Muraskin, Jordan; Sherwin, Jason; Lieberman, Gregory; Garcia, Javier O; Verstynen, Timothy; Vettel, Jean M; Sajda, Paul

    2017-01-01

    In the last few decades, non-invasive neuroimaging has revealed macro-scale brain dynamics that underlie perception, cognition and action. Advances in non-invasive neuroimaging target two capabilities; 1) increased spatial and temporal resolution of measured neural activity, and 2) innovative methodologies to extract brain-behavior relationships from evolving neuroimaging technology. We target the second. Our novel methodology integrated three neuroimaging methodologies and elucidated expertise-dependent differences in functional (fused EEG-fMRI) and structural (dMRI) brain networks for a perception-action coupling task. A set of baseball players and controls performed a Go/No-Go task designed to mimic the situation of hitting a baseball. In the functional analysis, our novel fusion methodology identifies 50ms windows with predictive EEG neural correlates of expertise and fuses these temporal windows with fMRI activity in a whole-brain 2mm voxel analysis, revealing time-localized correlations of expertise at a spatial scale of millimeters. The spatiotemporal cascade of brain activity reflecting expertise differences begins as early as 200ms after the pitch starts and lasting up to 700ms afterwards. Network differences are spatially localized to include motor and visual processing areas, providing evidence for differences in perception-action coupling between the groups. Furthermore, an analysis of structural connectivity revealed that the players have significantly more connections between cerebellar and left frontal/motor regions, and many of the functional activation differences between the groups are located within structurally defined network modules that differentiate expertise. In short, our novel method illustrates how multimodal neuroimaging can provide specific macro-scale insights into the functional and structural correlates of expertise development.

  6. Phenotypic and functional characterization of lymphocytes from different age groups of Bolivian squirrel monkeys (Saimiri boliviensis boliviensis.

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    Pramod N Nehete

    Full Text Available Due to many physiological and genetic characteristic similarities to humans, squirrel monkeys provide an ideal animal model specifically for studying malaria, and transmissible spongiform encephalopathies (Creutzfeldt-Jacob disease. While squirrel monkeys three years and older are generally considered adult subjects suitable for use in medical research studies, little is known about the functional properties of lymphocytes in relation to the age of these animals, which could significantly impact the quality and quantity of innate and adaptive immune responses. In this study, we investigated differences in the phenotype and function of lymphocytes subsets of young (3-4 years, adult (8-10 years and aged (16-19 years squirrel monkeys. In general, animals in all three age groups exhibited comparable numbers of different lymphocyte subsets except for CD20+ B cells that were significantly lower in aged relative to young animals and T cells subsets expressing both CD4 and CD8 (double positive were significantly higher in aged relative to young animals. With increasing age, phenotypic differences in central and effector memory T cells subsets were observed, that were more pronounced for the CD8+ T cells. Despite equal proportions of CD3+ T cells among the three age groups, responses of peripheral blood mononuclear cells to T cell mitogens PHA and Con A showed lower IFN-γ producing cells in the aged group than that in the young group. Furthermore, aged animals showed significantly higher plasma levels of inflammatory cytokines IL-6, IFN-γ, TNF-α, IL-10 and IL-12. These findings suggest that while the squirrel monkeys in general share phenotypic and functional similarities of lymphocyte subsets with humans in relation to age, specific differences exist in immune function of lymphocytes between young and old animals that could potentially impact experimental outcomes for which the measurement of immunologic endpoints are critical.

  7. NS4A protein as a marker of HCV history suggests that different HCV genotypes originally evolved from genotype 1b.

    Science.gov (United States)

    Sarwar, Muhammad T; Kausar, Humera; Ijaz, Bushra; Ahmad, Waqar; Ansar, Muhammad; Sumrin, Aleena; Ashfaq, Usman A; Asad, Sultan; Gull, Sana; Shahid, Imran; Hassan, Sajida

    2011-06-23

    The 9.6 kb long RNA genome of Hepatitis C virus (HCV) is under the control of RNA dependent RNA polymerase, an error-prone enzyme, for its transcription and replication. A high rate of mutation has been found to be associated with RNA viruses like HCV. Based on genetic variability, HCV has been classified into 6 different major genotypes and 11 different subtypes. However this classification system does not provide significant information about the origin of the virus, primarily due to high mutation rate at nucleotide level. HCV genome codes for a single polyprotein of about 3011 amino acids which is processed into structural and non-structural proteins inside host cell by viral and cellular proteases. We have identified a conserved NS4A protein sequence for HCV genotype 3a reported from four different continents of the world i.e. Europe, America, Australia and Asia. We investigated 346 sequences and compared amino acid composition of NS4A protein of different HCV genotypes through Multiple Sequence Alignment and observed amino acid substitutions C22, V29, V30, V38, Q46 and Q47 in NS4A protein of genotype 1b. Furthermore, we observed C22 and V30 as more consistent members of NS4A protein of genotype 1a. Similarly Q46 and Q47 in genotype 5, V29, V30, Q46 and Q47 in genotype 4, C22, Q46 and Q47 in genotype 6, C22, V38, Q46 and Q47 in genotype 3 and C22 in genotype 2 as more consistent members of NS4A protein of these genotypes. So the different amino acids that were introduced as substitutions in NS4A protein of genotype 1 subtype 1b have been retained as consistent members of the NS4A protein of other known genotypes. These observations indicate that NS4A protein of different HCV genotypes originally evolved from NS4A protein of genotype 1 subtype 1b, which in turn indicate that HCV genotype 1 subtype 1b established itself earlier in human population and all other known genotypes evolved later as a result of mutations in HCV genotype 1b. These results were further

  8. NS4A protein as a marker of HCV history suggests that different HCV genotypes originally evolved from genotype 1b

    Directory of Open Access Journals (Sweden)

    Asad Sultan

    2011-06-01

    Full Text Available Abstract Background The 9.6 kb long RNA genome of Hepatitis C virus (HCV is under the control of RNA dependent RNA polymerase, an error-prone enzyme, for its transcription and replication. A high rate of mutation has been found to be associated with RNA viruses like HCV. Based on genetic variability, HCV has been classified into 6 different major genotypes and 11 different subtypes. However this classification system does not provide significant information about the origin of the virus, primarily due to high mutation rate at nucleotide level. HCV genome codes for a single polyprotein of about 3011 amino acids which is processed into structural and non-structural proteins inside host cell by viral and cellular proteases. Results We have identified a conserved NS4A protein sequence for HCV genotype 3a reported from four different continents of the world i.e. Europe, America, Australia and Asia. We investigated 346 sequences and compared amino acid composition of NS4A protein of different HCV genotypes through Multiple Sequence Alignment and observed amino acid substitutions C22, V29, V30, V38, Q46 and Q47 in NS4A protein of genotype 1b. Furthermore, we observed C22 and V30 as more consistent members of NS4A protein of genotype 1a. Similarly Q46 and Q47 in genotype 5, V29, V30, Q46 and Q47 in genotype 4, C22, Q46 and Q47 in genotype 6, C22, V38, Q46 and Q47 in genotype 3 and C22 in genotype 2 as more consistent members of NS4A protein of these genotypes. So the different amino acids that were introduced as substitutions in NS4A protein of genotype 1 subtype 1b have been retained as consistent members of the NS4A protein of other known genotypes. Conclusion These observations indicate that NS4A protein of different HCV genotypes originally evolved from NS4A protein of genotype 1 subtype 1b, which in turn indicate that HCV genotype 1 subtype 1b established itself earlier in human population and all other known genotypes evolved later as a result of

  9. Immunoglobulin diversity in the phylogenetically primitive shark, Heterodontus francisci. Suggested lack of structural variation between light chains isolated from different animals.

    Science.gov (United States)

    Litman, G W; Scheffel, C; Gerber-Jenson, B

    1980-06-01

    A two-step procedure employing gel filtration and anion exchange chromatography has been utilized to isolate LMW immunoglobulin from the horned shark, Heterodontus francisci. Light chains obtained by complete reduction and alkylation of the parent protein have been compared by several analytical techniques. Amino acid composition data implies a limited degree of variation in the light chains isolated from individual animals. Polyacrylamide gel electrophoresis of the CNBr digests of the light chains reveal indistinguishable banding profiles of the major peptides. Isoelectric focusing indicates limited heterogeneity in the light chain spectrotype and identity in the pI of the majority of bands detectable by staining. The suggested degree of structural similarity in the light chains of this phylogenetically primitive shark is discussed in terms of the evolutionary position of the species and current theories concerning the origins of structural diversity in immunoglobulins.

  10. Slope variation and population structure of tree species from different ecological groups in South Brazil

    Directory of Open Access Journals (Sweden)

    Edmilson Bianchini

    2010-09-01

    Full Text Available Size structure and spatial arrangement of 13 abundant tree species were determined in a riparian forest fragment inParaná State, South Brazil (23"16'S and 51"01'W. The studied species were Aspidosperma polyneuron Müll. Arg., Astronium graveolens Jacq. and Gallesia integrifolia (Spreng Harms (emergent species; Alseis floribunda Schott, Ruprechtia laxiflora Meisn. and Bougainvillea spectabilis Willd. (shade-intolerant canopy species; Machaerium paraguariense Hassl, Myroxylum peruiferum L. and Chrysophyllum gonocarpum (Mart. & Eichler ex Miq. Engl. (shade-tolerant canopy species; Sorocea bonplandii (Baill. Bürger, Trichilia casaretti C. Dc, Trichilia catigua A. Juss. and Actinostemon concolor (Spreng. Müll. Arg. (understory small trees species. Height and diameter structures and basal area of species were analyzed. Spatial patterns and slope correlation were analyzed by Moran's / spatial autocorrelation coefficient and partial Mantel test, respectively. The emergent and small understory species showed the highest and the lowest variations in height, diameter and basal area. Size distribution differed among emergent species and also among canopy shade-intolerant species. The spatial pattern ranged among species in all groups, except in understory small tree species. The slope was correlated with spatial pattern for A. polyneuron, A. graveolens, A. floribunda, R. laxiflora, M. peruiferum and T. casaretti. The results indicated that most species occurredin specific places, suggesting that niche differentiation can be an important factor in structuring the tree community.Visando contribuir para o conhecimento das estratégias devida de espécies em fragmentos florestais, foram determinadas as estruturas de tamanho e espacial de 13 espécies arbóreas do remanescente de floresta ciliar no Estado do Paraná, no Sul do Brasil (23"16'S e 51"01'W. Foram analisadas as espécies: Aspidosperma polyneuron Müll. Arg., Astronium graveolens Jacq. e Gallesia

  11. Solitary expression of CD7 among T-cell antigens in acute myeloid leukemia: identification of a group of patients with similar T-cell receptor beta and delta rearrangements and course of disease suggestive of poor prognosis

    DEFF Research Database (Denmark)

    Jensen, A W; Hokland, M; Jørgensen, H

    1991-01-01

    to the French-American-British type M4, and four were under the age of 40. Despite intensive chemotherapy, four never obtained a complete remission and the fifth died of relapse after an allogenic bone marrow transplantation. While 12 randomly selected T-cell antigen negative AML patients showed only few....... These data suggest that the solitary presence of CD7 among T-cell antigens in otherwise clearcut AML cases identifies a group of patients with similarities in antigen receptor gene configuration as well as outcome. Udgivelsesdato: 1991-Sep-1...

  12. Differences in morphological properties between the olivine group minerals formed in natural and industrial processes

    Directory of Open Access Journals (Sweden)

    Dević S.

    2007-01-01

    Full Text Available Olivines are a large isomorphic series of minerals, belonging to silicates group. Regardless of their chemical composition, any of these minerals can be formed both in natural and industrial processes. The aim of this work is to describe these minerals and differences of morphological properties between the olivines formed in nature, and those formed as byproducts of some industrial processes , as Process Metalurgy-Ironmaking. The olivines whose formation is tied to rock masses (natural process and the olivines genetically tied to industrial processes of black metallurgy slags (process metallurgy-Ironmaking are shown in this paper. The morphological properties of these minerals and their differences have been analyzed by optical microscopy in refracted and in reflected light. .

  13. Single Alternating Group Explicit (SAGE) Method for Electrochemical Finite Difference Digital Simulation

    Institute of Scientific and Technical Information of China (English)

    DENG,Zhao-Xiang(邓兆祥); LIN,Xiang-Qin(林祥钦); TONG,Zhong-Hua(童中华)

    2002-01-01

    The four different schemes of Group Explicit Method (GEM): GER, GEL, SAGE and DAGE have been claimed to be unstable when employed for electrochemical digital simulations with large model diffusion coefficient DM@ However, in this investigation, in spite of the conditional stability of GER and GEL, the SAGE scheme, which is a combination of GEL and GER, was found to be unconditionally stable when used for simulations of electrochemical reaction-diffusions and had a performance comparable with or even better than the Fast Quasi Explicit Finite Difference Method (FQEFD) in srme aspects. Corresponding differential equations of SAGE scheme for digital simulations of various electrochemical mechanisms with both uniform and exponentially expanded space units were established. The effectiveness of the SAGE method was further demonstrated by the simulations of an EC and a catalytic mechanism with very large homogoneous rate constants.

  14. Microtribological study of perfluoropolyether with different functional groups coated on hydrogen terminated Si

    Energy Technology Data Exchange (ETDEWEB)

    Minn, Myo; Satyanarayana, Nalam [Department of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117576 (Singapore); Sinha, Sujeet K., E-mail: mpesks@nus.edu.sg [Department of Mechanical Engineering, National University of Singapore, 9 Engineering Drive 1, Singapore 117576 (Singapore); Kondo, Hirofumi [Sony Chemical and Information Device Corporation, R and D Division, 1078 Kamiishikawa, Kanuma 322-8503 (Japan)

    2012-01-15

    Friction and wear properties of different perfluoropolyether (PFPE) films with and without hydrogen termination on Si (Si-H) were studied using a ball-on-disk tribometer. The physical and chemical properties of the films were evaluated using contact angle measurement, atomic force microscopy and X-ray photoelectron spectroscopy. Coating of PFPEs onto bare Si has lowered the coefficient of friction (from 0.6 for Si to {approx}0.05 with PFPE) and enhanced the wear durability (20,000 times) in comparison with those for bare Si which failed immediately. The introduction of hydrogen termination onto Si prior to PFPE coating has further increased the wear durability of PFPE with different functional groups several times (>5 times) under a normal load of 30 mN and a sliding speed of 0.052 m/s.

  15. The analysis of core and symbiotic genes of rhizobia nodulating Vicia from different continents reveals their common phylogenetic origin and suggests the distribution of Rhizobium leguminosarum strains together with Vicia seeds.

    Science.gov (United States)

    Alvarez-Martínez, Estela R; Valverde, Angel; Ramírez-Bahena, Martha Helena; García-Fraile, Paula; Tejedor, Carmen; Mateos, Pedro F; Santillana, Nery; Zúñiga, Doris; Peix, Alvaro; Velázquez, Encarna

    2009-08-01

    In this work, we analysed the core and symbiotic genes of rhizobial strains isolated from Vicia sativa in three soils from the Northwest of Spain, and compared them with other Vicia endosymbionts isolated in other geographical locations. The analysis of rrs, recA and atpD genes and 16S-23S rRNA intergenic spacer showed that the Spanish strains nodulating V. sativa are phylogenetically close to those isolated from V. sativa and V. faba in different European, American and Asian countries forming a group related to Rhizobium leguminosarum. The analysis of the nodC gene of strains nodulating V. sativa and V. faba in different continents showed they belong to a phylogenetically compact group indicating that these legumes are restrictive hosts. The results of the nodC gene analysis allow the delineation of the biovar viciae showing a common phylogenetic origin of V. sativa and V. faba endosymbionts in several continents. Since these two legume species are indigenous from Europe, our results suggest a world distribution of strains from R. leguminosarum together with the V. sativa and V. faba seeds and a close coevolution among chromosome, symbiotic genes and legume host in this Rhizobium-Vicia symbiosis.

  16. Ethnic Group Differences in Health Outcomes Among Asian American Men in California.

    Science.gov (United States)

    Mui, Paulani; Bowie, Janice V; Juon, Hee-Soon; Thorpe, Roland J

    2017-09-01

    The numbers of Asian American men are continually increasing, yet limited research exists on this understudied population. Addressing this lack of research is necessary to better inform how best to improve quality of care. This study examined health outcome differences across ethnically diverse groups of Asian American men in California, compared with non-Hispanic White men. Using data from the 2007, 2009, and 2011-2012 California Health Interview Survey, distributions of health status and health-related characteristics across ( n = 43,030) racial/ethnic groups of men (Chinese, Japanese, Korean, Filipino, Vietnamese, Other Asian Americans, and non-Hispanic Whites) were calculated. Compared with non-Hispanic Whites, odds of reporting fair or poor health were higher among Vietnamese, while odds of diabetes were higher among Korean, Filipino, and Other Asian Americans. Odds of high blood pressure were higher among Filipino and Vietnamese but lower among Other Asian Americans, while odds of disability were lower across all ethnic groups except Filipino and Vietnamese. This study's findings highlight the importance of understanding ethnic heterogeneity to develop culturally appropriate health interventions for Asian American men.

  17. SOMO (SOlution MOdeler) differences between X-Ray- and NMR-derived bead models suggest a role for side chain flexibility in protein hydrodynamics.

    Science.gov (United States)

    Rai, Nithin; Nöllmann, Marcelo; Spotorno, Bruno; Tassara, Giovanni; Byron, Olwyn; Rocco, Mattia

    2005-05-01

    Reduced numbers of frictional/scattering centers are essential for tractable hydrodynamic and small-angle scattering data modeling. We present a method for generating medium-resolution models from the atomic coordinates of proteins, basically by using two nonoverlapping spheres of differing radii per residue. The computed rigid-body hydrodynamic parameters of BPTI, RNase A, and lysozyme models were compared with a large database of critically assessed experimental values. Overall, very good results were obtained, but significant discrepancies between X-ray- and NMR-derived models were found. Interestingly, they could be accounted for by properly considering the extent to which highly mobile surface side chains differently affect translational/rotational properties. Models of larger structures, such as fibrinogen fragment D and citrate synthase, also produced consistent results. Foremost among this method's potential applications is the overall conformation and dynamics of modular/multidomain proteins and of supramolecular complexes. The possibility of merging data from high- and low-resolution structures greatly expands its scope.

  18. Comparison of cytological parameters of exfoliated buccal mucosal cells in different temperament groups

    Directory of Open Access Journals (Sweden)

    Zahra Zendehboodi

    2017-05-01

    Full Text Available Introduction: Temperament (Mizaj forms the basic concept of Iranian traditional medicine (ITM, and greatly influences the diagnosis and treatment of diseases, as well as maintains the ideal healthy state of an individual. In particular, temperament is presumed to affect the morphological, physiological, and psychological features of a person; however, its influence on biological features remains unclear in practical ITM. This study aimed to evaluate the association between the temperament and the cytological features of buccal mucosa in healthy people. Methods: The study sample included 75 healthy individuals from Fars province, southern Iran. The temperament was determined using a self-reported temperament identification scale. Based on the questionnaire, volunteers were classified in nine temperaments including one equilibrium, four simple temperaments (warm, cold, moist, and dry, and four combined temperaments (warm–moist, warm–dry, cold–moist, cold–dry. Smears collected from the buccal mucosa of participants were analyzed for biomarkers of DNA damage, cytokinetic defects, proliferative potential, and cell death using micronucleus (MN assay. Student’s t-test or Mann–Whitney U test was applied to identify the differences between groups. Results: DNA damage (nuclear buds and cell death biomarkers (condensed chromatin, karyorrhexic, pyknotic, and karyolitic cells reported significant differences between certain temperament groups. Conclusions: The present study reported that the aforementioned cytological parameters could be affected by the temperament; however, more studies with greater sample sizes are warranted.

  19. Epidemiological differences of lower urinary tract symptoms among female subpopulations and group level interventions

    Directory of Open Access Journals (Sweden)

    Avasarala Atchuta Kameswararao

    2008-01-01

    Full Text Available Objectives: 1 To study the risk factor profiles of lower urinary tract symptoms (LUTS among adolescent girls, housewives and working women and its socioeconomic and quality of life losses. 2 To undertake risk factor modifications using the adolescent girls. Design and Setting: Cross-sectional descriptive study followed by educational intervention. Statistical Methods: Cluster sampling, Proportions, confidence intervals, Chi square and t-Tests and Logistic regression. Materials and Methods: House to house survey was done in two villages and one urban ward. Seventy-five housewives, 75 working women and 180 adolescent girls were asked about the risk factors and losses due to LUTS. Three teams of adolescent girls were utilized to bring about behavioral modifications. Impact was measured through user perspectives obtained from the participants. Results: Risk factors, social, economic and quality of life losses were different among the three female populations. Overall prevalence of LUTS among the three groups is 61(18.5%. Improper anal washing technique, malnutrition, presence of vaginal discharge, use of unsanitary menstrual pads, pinworm infestation and use of bad toilets were the significant causes among girls. Presence of sexually transmitted diseases was a contributing factor among housewives and working women. Prolonged sitting the posture was also contributing to LUTS among working women. Seventy-four per cent of beneficiaries expressed that intervention is useful. Conclusions: The causes for LUTS and their consequences were differing among the three female subpopulations. Specific group level interventions using trained girls were successful.

  20. Different genetic algorithms and the evolution of specialization: a study with groups of simulated neural robots.

    Science.gov (United States)

    Ferrauto, Tomassino; Parisi, Domenico; Di Stefano, Gabriele; Baldassarre, Gianluca

    2013-01-01

    Organisms that live in groups, from microbial symbionts to social insects and schooling fish, exhibit a number of highly efficient cooperative behaviors, often based on role taking and specialization. These behaviors are relevant not only for the biologist but also for the engineer interested in decentralized collective robotics. We address these phenomena by carrying out experiments with groups of two simulated robots controlled by neural networks whose connection weights are evolved by using genetic algorithms. These algorithms and controllers are well suited to autonomously find solutions for decentralized collective robotic tasks based on principles of self-organization. The article first presents a taxonomy of role-taking and specialization mechanisms related to evolved neural network controllers. Then it introduces two cooperation tasks, which can be accomplished by either role taking or specialization, and uses these tasks to compare four different genetic algorithms to evaluate their capacity to evolve a suitable behavioral strategy, which depends on the task demands. Interestingly, only one of the four algorithms, which appears to have more biological plausibility, is capable of evolving role taking or specialization when they are needed. The results are relevant for both collective robotics and biology, as they can provide useful hints on the different processes that can lead to the emergence of specialization in robots and organisms.

  1. WMS-III performance in patients with temporal lobe epilepsy: group differences and individual classification.

    Science.gov (United States)

    Wilde, N; Strauss, E; Chelune, G J; Loring, D W; Martin, R C; Hermann, B P; Sherman, E; Hunter, M

    2001-11-01

    The utility of the WMS-III in detecting lateralized impairment was examined in a large sample of patients with temporal lobe epilepsy. Methods of analysis included evaluation of group means on the various indexes and subtest scores, the use of ROC curves, and an examination of Auditory-Visual Index discrepancy scores. In addition, performance on immediate and delayed indexes in the auditory and the visual modality was compared within each group. Of the WMS-III scores, the Auditory-Visual Delayed Index difference score appeared most sensitive to side of temporal dysfunction, although patient classification rates were not within an acceptable range to have clinical utility. The ability to predict laterality based on statistically significant index score differences was particularly weak for those with left temporal dysfunction. The use of unusually large discrepancies led to improved prediction, however, the rarity of such scores in this population limits their usefulness. Although the utility of the WMS-III in detecting laterality may be limited in preoperative cases, the WMS-III may still hold considerable promise as a measure of memory in documenting baseline performance and in detecting those that may be at risk following surgery.

  2. THE INFLUENCE OF AGE HENS ON THE INTENSITY LOAD CAPACITY FROM DIFFERENT WEIGHT GROUPS EGGS

    Directory of Open Access Journals (Sweden)

    Tatjana Pandurević

    2015-05-01

    Full Text Available The aim of this study was to determine the effect of age of hens on the intensity of load from different weight groups eggs. This paper presents the correlation connection, meaning and significance of differences connection for two weight classes (M - 53 to 63g and L – 63g to 73g, which make up the largest part of the total number of eggs produced during the entire production cycle, as well as for all of the eggs produced, as compared to age-laying hens. Between age and intensity of load to 53 weeks of age hens (SN53/34, there is a strong positive, medium and slight correlation coefficients determined and phenotypic correlation are statistically confirmed at the level of P <0.01 and P <0.05. From 53 weeks of age until the end of exploitation of laying hens (SN72/53 the correlation strength of the association was weaker and weaker, and in the last eight weeks passed in the negative, ie. Fortified negative phenotypic correlation coefficients, but were not statistically significant (P> 0.05. Between the age of hens and intensity of load hardest groups (classes eggs (L there is a complete and very strong connections and established correlation coefficients were statistically significant at P <0.001.

  3. Childhood Trauma Questionnaire (CTQ) in Brazilian Samples of Different Age Groups: Findings from Confirmatory Factor Analysis

    Science.gov (United States)

    Grassi-Oliveira, Rodrigo; Cogo-Moreira, Hugo; Salum, Giovanni Abrahão; Brietzke, Elisa; Viola, Thiago Wendt; Manfro, Gisele Gus; Kristensen, Christian Haag; Arteche, Adriane Xavier

    2014-01-01

    The Childhood Trauma Questionnaire (CTQ) is internationally accepted as a key tool for the assessment of childhood abuse and neglect experiences. However, there are relative few psychometric studies available and some authors have proposed two different factor solutions. We examined the dimensional structure and internal consistency of the Brazilian version of the CTQ. A total of 1,925 participants from eight different clinical and non-clinical samples including adolescents, adults and elders were considered in this study. First, we performed Confirmatory Factor Analysis to investigate the goodness of fit of the two proposed competitive factor structure models for the CTQ. We also investigated the internal consistency of all factors. Second, multi-group analyses were used to investigate measurement invariance and population heterogeneity across age groups and sex. Our findings revealed that the alternative factor structure as opposed to the original factor structure was the most appropriate model within adolescents and adults Brazilian samples. We provide further evidence for the validity and reliability of the CTQ within the Brazilian samples and report that the alternative model showed an improvement in fit indexes and may be a better alternative over the original model. PMID:24475237

  4. Domesticated horses differ in their behavioural and physiological responses to isolated and group housing.

    Science.gov (United States)

    Yarnell, Kelly; Hall, Carol; Royle, Chris; Walker, Susan L

    2015-05-01

    The predominant housing system used for domestic horses is individual stabling; however, housing that limits social interaction and requires the horse to live in semi-isolation has been reported to be a concern for equine welfare. The aim of the current study was to compare behavioural and physiological responses of domestic horses in different types of housing design that provided varying levels of social contact. Horses (n = 16) were divided equally into four groups and exposed to each of four housing treatments for a period of five days per treatment in a randomized block design. The four housing treatments used were single housed no physical contact (SHNC), single housed semi-contact (SHSC), paired housed full contact (PHFC) and group housed full contact (GHFC). During each housing treatment, adrenal activity was recorded using non-invasive faecal corticosterone metabolite analysis (fGC). Thermal images of the eye were captured and eye temperature was assessed as a non-invasive measure of the stress response. Behavioural analysis of time budget was carried out and an ease of handling score was assigned to each horse in each treatment using video footage. SHNC horses had significantly higher (p = 0.01) concentrations of fGC and were significantly (p = 0.003) more difficult to handle compared to the other housing types. GHFC horses, although not significantly different, had numerically lower concentrations of fGC and were more compliant to handling when compared to all other housing treatments. Eye temperature was significantly (p = 0.0001) lower in the group housed treatment when compared to all other treatments. These results indicate that based on physiological and behavioural measures incorporating social contact into the housing design of domestic horses could improve the standard of domestic equine welfare.

  5. Evaluation of Public E-Services and Information Technology Accessibility in Different Social Groups

    Directory of Open Access Journals (Sweden)

    Ramutė Naujikienė

    2012-12-01

    Full Text Available The purpose of this study is to develop an approach based on the social quality evaluation square model for evaluation of information technology usage in different social groups. Componential view to the accessibility of e-services including IT means providing the possibility to research the influences of different life conditions to usage of the public e-services. The task of this empirical study is directed towards revealing the differences of e-inclusion and e-services accessibility for social groups of citizens of Lithuania, and to compare this accessibility data with other EU countries.Design/methodology/approach—the approach is based on the square model of social quality evaluation of information technology usage in different social groups. The social division square model includes an assessment of quality according to the evaluation of socioeconomic security, social inclusion, social cohesion, and empowerment. Empowerment can be defined as consisting of individual or collective decisions to act on one’s own life.Findings—the results are demonstrated by the accessibility of public e-services data, which are evaluated by the quality of social group development according to IT applications. The hypothesis was confirmed that the e-government activities can be realized by properly selecting and installing technologies, and using technology facilities. E-services influence the capabilities of state officials to apply modern technology and increase the availability of e-services for social groups. Results consist of individual or collective decisions to act on one’s own life, to implementation of effective information technologies in the e-government activities and using of e-services. An important indicator is the implementation of e-services in the activity of citizens. It is submitted as the index of e-participation in dealing with the activities of citizens and the possibilities of authorities directly related with providing services

  6. Analyzing individual and group differences in multijoint multiwaveform gait data using the Parafac2 model.

    Science.gov (United States)

    Helwig, Nathaniel E; Hong, Sungjin; Bokhari, Ehsan

    2013-01-01

    Locomotion research often involves analyzing multiwaveform data (e.g., velocities, accelerations, etc.) from various body locations (e.g., knees, ankles, etc.) of several subjects. Therefore, some multivariate technique such as principal component analysis is often used to examine interrelationships between the many correlated waveforms. Despite its extensive use in locomotion research, principal component analysis is for two-mode data, whereas locomotion data are typically collected in higher mode form. In this paper, we present the benefits of analyzing four-mode locomotion data (subjects × time × joints × waveforms) using the Parafac2 model, which is a component model designed for analyzing variation in multimode data. Using bilateral hip, knee, and ankle angular displacement, velocity, and acceleration waveforms, we demonstrate Parafac2's ability to produce interpretable components describing (i) the fundamental patterns of variation in lower limb angular kinematics during healthy walking and (ii) the fundamental differences between normal and atypical subjects' multijoint multiwaveform locomotive patterns. Also, we illustrate how Parafac2 makes it possible to determine which waveforms best characterize the individual and/or group differences captured by each component. Our results indicate that different waveforms should be used for different purposes, confirming the need for the holistic analysis of multijoint multiwaveform locomotion data, particularly when investigating atypical motion patterns.

  7. Differences in incidence and co-occurrence of vaccine and nonvaccine human papillomavirus types in Finnish population before human papillomavirus mass vaccination suggest competitive advantage for HPV33.

    Science.gov (United States)

    Merikukka, Marko; Kaasila, Marjo; Namujju, Proscovia B; Palmroth, Johanna; Kirnbauer, Reinhard; Paavonen, Jorma; Surcel, Heljä-Marja; Lehtinen, Matti

    2011-03-01

    To understand likelihood of type replacement after vaccination against the high-risk human papillomavirus (HPV) types, we evaluated competition of the seven most common genital HPV types in a population sample of unvaccinated, fertile-aged Finnish women. First trimester sera from two consecutive pregnancies were retrieved from 3,183 Finnish women (mean age, 23.1 years) of whom 42.3% had antibodies to at least one HPV type (6/11/16/18/31/33/45) at the baseline. Antibody positivity to more than one HPV types by the second pregnancy was common among the baseline HPV seropositives. However, compared to baseline HPV-seronegative women, significantly increased incidence rate ratios (IRRs), indicating an increased risk to seroconvert for another HPV type, were consistently noted only for HPV33 among baseline HPV16 or HPV18 antibody (ab)-positive women: HPV(16ab only) (→) (16&33ab) IRR 2.9 [95% confidence interval (CI) 1.6-5.4] and HPV(18ab only) (→) (18&33ab) IRR 2.5 (95% CI 1.1-6.0), irrespectively of the presence of antibodies to other HPV types at baseline: HPV(16ab) (→) (16&33ab) IRR 3.2 (95% CI 2.0-5.2) and HPV(18ab) (→) (18&33ab) IRR 3.6 (95% CI 2.1-5.9). Our findings suggest a possible competitive advantage for HPV33 over other genital HPV types in the unvaccinated population. HPV33 should be monitored for type replacement after HPV mass vaccination. Copyright © 2010 UICC.

  8. Comparative analyses of plastid and AFLP data suggest different colonization history and asymmetric hybridization between Betula pubescens and B. nana.

    Science.gov (United States)

    Eidesen, Pernille Bronken; Alsos, Inger Greve; Brochmann, Christian

    2015-08-01

    Birches (Betula spp.) hybridize readily, confounding genetic signatures of refugial isolation and postglacial migration. We aimed to distinguish hybridization from range-shift processes in the two widespread and cold-adapted species B. nana and B. pubescens, previously shown to share a similarly east-west-structured variation in plastid DNA (pDNA). We sampled the two species throughout their ranges and included reference samples of five other Betula species and putative hybrids. We analysed 901 individual plants using mainly nuclear high-resolution markers (amplified fragment length polymorphisms; AFLPs); a subset of 64 plants was also sequenced for two pDNA regions. Whereas the pDNA variation as expected was largely shared between B. nana and B. pubescens, the two species were distinctly differentiated at AFLP loci. In B. nana, both the AFLP and pDNA results corroborated the former pDNA-based hypothesis that it expanded from at least two major refugia in Eurasia, one south of and one east of the North European ice sheets. In contrast, B. pubescens showed a striking lack of geographic structuring of its AFLP variation. We identified a weak but significant increase in nuclear (AFLP) gene flow from B. nana into B. pubescens with increasing latitude, suggesting hybridization has been most frequent at the postglacial expansion front of B. pubescens and that hybrids mainly backcrossed to B. pubescens. Incongruence between pDNA and AFLP variation in B. pubescens can be explained by efficient expansion from a single large refugium combined with leading-edge hybridization and plastid capture from B. nana during colonization of new territory already occupied by this more cold-tolerant species.

  9. Phytoplankton communities from San Francisco Bay Delta respond differently to oxidized and reduced nitrogen substrates - even under conditions that would otherwise suggest nitrogen sufficiency

    Directory of Open Access Journals (Sweden)

    Patricia M Glibert

    2014-07-01

    Full Text Available The effect of equivalent additions of nitrogen (N, 30-40 μM-N in different forms (ammonium, NH4+, and nitrate, NO3- under conditions of different light exposure on phytoplankton community composition was studied in a series of four, 5-day enclosure experiments on water collected from the nutrient-rich San Francisco Bay Delta over two years. Overall, proportionately more chlorophyll a and fucoxanthin (generally indicative of diatoms was produced per unit N taken up in enclosures enriched with NO3- and incubated at reduced (~15% of ambient light intensity than in treatments with NO3- with high (~60% of ambient light exposure or with NH4+ under either light condition. In contrast, proportionately more chlorophyll b (generally indicative of chlorophytes and zeaxanthin (generally indicative of cyanobacteria was produced in enclosures enriched with NH4+ and incubated under high light intensity than in treatments with low light or with added NO3- at either light level. Rates of maximal velocities (Vmax of uptake of N substrates, measured using 15N tracer techniques, in all enclosures enriched with NO3- were higher than those enriched with NH4+. Directionality of trends in enclosures were similar to phytoplankton community shifts observed in transects of the Sacramento River to Suisun Bay, a region in which large changes in total N quantity and form occur. These data substantiate the growing body of experimental evidence that dichotomous microbial communities develop when enriched with the same absolute concentration of oxidized vs. reduced N forms, even when sufficient N nutrient was available to the community prior to the N inoculations.

  10. A quantitative review of ethnic group differences in experimental pain response: do biology, psychology, and culture matter?

    Science.gov (United States)

    Rahim-Williams, Bridgett; Riley, Joseph L; Williams, Ameenah K K; Fillingim, Roger B

    2012-04-01

    Pain is a subjectively complex and universal experience. We examine research investigating ethnic group differences in experimental pain response and factors contributing to group differences. We conducted a systematic literature review and analysis of studies using experimental pain stimuli to assess pain sensitivity across multiple ethnic groups. Our search covered the period from 1944 to 2011, and used the PubMed bibliographic database; a reference source containing over 17 million citations. We calculated effect sizes; identified ethnic/racial group categories, pain stimuli, and measures; and examined findings regarding biopsychosociocultural factors contributing to ethnic/racial group differences. We found 472 studies investigating ethnic group differences and pain. Twenty-six of these met our review inclusion criteria of investigating ethnic group differences in experimental pain. The majority of studies included comparisons between African Americans (AA) and non-Hispanic Whites (NHW). There were consistently moderate to large effect sizes for pain tolerance across multiple stimulus modalities; AA demonstrated lower pain tolerance. For pain threshold, findings were generally in the same direction, but effect sizes were small to moderate across ethnic groups. Limited data were available for suprathreshold pain ratings. A subset of studies comparing NHW and other ethnic groups showed a variable range of effect sizes for pain threshold and tolerance. There are potentially important ethnic/racial group differences in experimental pain perception. Elucidating ethnic group differences has translational merit for culturally competent clinical care and for addressing and reducing pain treatment disparities among ethnically/racially diverse groups. Wiley Periodicals, Inc.

  11. The success of medical nutrition therapy in both genders and in different age groups

    Directory of Open Access Journals (Sweden)

    Ralević Slađana

    2013-01-01

    Full Text Available More than half of the adult population of the Republic of Serbia is overweight or obese. Obesity carries various risks and general health complications, which can significantly impair one's functioning and well-being. On the other hand, beneficial effects of body mass reduction are clearly confirmed. The therapeutic approach to obesity involves the use of various measures Treatment may include: medical nutrition therapy, programmed physical activity, medicaments and surgical treatment. The aim of this study was to examine if the effectiveness of medical nutrition therapy depends on the sex and age structure. This investigation was conducted as a retrospective study for the period from January 2008. until July 2009. During this time, 990 people came to the Counceling center. Only patients who came regularly to the controls and had BMI higher than 25 kg/m2 were included in this study. The average BMI in men was 31.55 kg/m2 and 32.66 kg/m2 in women. Compared to the first examination, majority of females (n = 35, 24.56% and males (n = 23, 25.27% reduced their BMI from 0 to 0.5 kg/m2 after medical nutrition therapy. Based on the results of X2 test, we concluded that there were statistically significant differences between men and women in effectiveness of medical nutrition therapy, while differences in the effectiveness of treatment in different age groups do not exist, neither in men nor in women.

  12. Prevalence of cytomegalovirus infection in different patient groups of a urban university in Brazil

    Directory of Open Access Journals (Sweden)

    José Hermôgenes Rocco Suassuna

    1995-06-01

    Full Text Available This study sought for etndence of previous CMV infection in patients of a general hospital serving the low income population of Rio de Janeiro. An enzyme immunoassay was used to detect anti-CMV antibodies in 713 typical hospital patients classified into eight different groups. Positive tests were found in 87% of pregnant women, 85% of newborns, 61% of pediatric patients, 77% of adolescent patients, 81% of adult patients, 87% of dialysed transplant candidates, 89% of kidney donors, and 92% of patients after transplantation. Depending of the subgroup studied these results carry different meanings and necessitate different clinical approaches. The risk of congenital disease is probably low in view of the reduced number of pregnant women still susceptible to primary infection. The number of primary infections will also be low in transplant recipients. However, those still susceptible will almost certainly acquire the infection from, their donor. Prophylactic CMV matching in kidney transplantation is not a realistic approach due to the low probability of finding pairs of seronegative donors and recipients.

  13. The epidemiology of observed temperament: Factor structure and demographic group differences.

    Science.gov (United States)

    Willoughby, Michael T; Stifter, Cynthia A; Gottfredson, Nisha C

    2015-05-01

    This study investigated the factor structure of observational indicators of children's temperament that were collected across the first three years of life in the Family Life Project (N=1205) sample. A four-factor model (activity level, fear, anger, regulation), which corresponded broadly to Rothbart's distinction between reactivity and regulation, provided an acceptable fit the observed data. Tests of measurement invariance demonstrated that a majority of the observational indicators exhibited comparable measurement properties for male vs. female, black vs. white, and poor vs. not-poor children, which improved the generalizability of these results. Unadjusted demographic group comparisons revealed small to moderate sized differences (Cohen ds=|.23-.42|) in temperamental reactivity and moderate to large sized differences (Cohen ds=-.64--.97) in regulation. Collectively, demographic variables explained more of the variation in regulation (R(2)=.25) than in reactivity (R(2)=.02-.06). Follow-up analyses demonstrated that race differences were substantially diminished in magnitude and better accounted for by poverty. These results help to validate the distinction between temperamental reactivity and regulation using observational indicators.

  14. Relative position of the mandibular foramen in different age groups of children: A radiographic study

    Directory of Open Access Journals (Sweden)

    Poonacha K

    2010-09-01

    Full Text Available Objectives: To assess the relative position of the mandibular foramen (MF and to evaluate the measurement of gonial angle (GoA and its relationship with distances between different mandibular borders in growing children between 3 and 13years of dental age. Materials and methods: The radiographs were traced to arrive at six linear and two angular measurements from which the relative position of the MF was assessed and compared in different age groups to determine the growth pattern of the mandible and changes in the location of the MF. Results: The distances between the MF and the anterior plane of the ramus were greater than that between MF and posterior plane of the ramus through all stages. There was a maximum increase in the vertical dimensions of the mandible compared with the horizontal dimensions, particularly in the late mixed dentition period. Conclusion: The mandible and its growth did not alter the position of the MF, both vertically and horizontally, in relation to different landmarks, and more obtuse GoA indicated an increased growth potential of the mandible. This has major implications in the inferior alveolar nerve block technique when used in children.

  15. Difference between the attitudes towards minority groups among parents and their children

    Directory of Open Access Journals (Sweden)

    Mićević Jelena

    2005-01-01

    Full Text Available The aim of this research is to establish if there are differences between discrimination attitudes of parents and their children towards various marginal groups (the Chinese, Roma, the rich, the poor, persons of different sex, disabled persons. 849 persons were examined in this research: 310 of children and 539 of parents. The questionnaire of identical form for parents and their children was used to examine these discrimination attitudes. The questionnaire contains the open-type questions and it is the part of questionnaire used in the investigation project of wider range. Independent estimators in the scale from 1 to 6 quantified these qualitative results obtained on the basis of open-type questions, by determine the intensity of these attitudes (in negative direction. So-called Canonical discrimination analysis was used, out of statistical methods. The obtained results show that parents and their children statistically differ significantly in discrimination attitudes towards the Chinese, male persons and disabled persons. Children express discrimination attitudes towards male sex and towards disabled persons, but do not have considerable discrimination attitudes towards the Chinese, but parents express discrimination attitudes towards the Chinese, but do not have considerable discrimination attitudes towards the male sex and towards disabled persons.

  16. Sexual peculiarities of lymphoid formations in trachea and bronchi of individuals of different age groups

    Directory of Open Access Journals (Sweden)

    V.B. Shadlinsky

    2010-03-01

    Full Text Available The aim of the investigation is to study the sexual peculiarities of lymphoid formations in trachea and bronchi of individuals of different age groups. The lymphoid apparatus of trachea and bronchi has been studied. taken from 58 humans of different age and both sexes, died or perished in accidents without pathologies of respiratory and immune systems was studied via microscopical methods. The trachea and bronchi principalis were fixated in 10% solution of formalin and in water Karnua. The longitudinal and transverse pieces were taken from cartilaginous and membranaceus walls of the upper, middle and lower one-third of the trachea and each bronchi principalis. These cuts 5-7 urn in thickness were stained with hematoxylin-eosin, azure-2-eosin, with hematoxylin-picrofucsin by Van-Gizon technique, with methyl green-pironin by Brashe technique (after fixation in water Karnua and reaction by Grymelius. The results of the research showed that during postnatal ontogenesis the sex related differences are observed in cell composition of the trachea and bronchi princiapalis' lymphoid structures. In adolescent, juvenile and 1-st mature period in females the percentage of small and big lymphocytes, cells with mitosis, plasma cells is more, but the percentage of medium lymphocytes and cells with degeneration is less than in males

  17. Visual acuity and refraction by age for children of three different ethnic groups in Paraguay

    Directory of Open Access Journals (Sweden)

    Marissa Janine Carter

    2013-04-01

    Full Text Available PURPOSE: To characterize refractive errors in Paraguayan children aged 5-16 years and investigate effect of age, gender, and ethnicity. METHODS:The study was conducted at 3 schools that catered to Mennonite, indigenous, and mixed race children. Children were examined for presenting visual acuity, autorefraction with and without cycloplegia, and retinoscopy. Data were analyzed for myopia and hyperopia (SE ≤-1 D or -0.5 D and ≥2 D or ≥3 D and astigmatism (cylinder ≥1 D. Spherical equivalent (SE values were calculated from right eye cycloplegic autorefraction data and analyzed using general linear modelling. RESULTS: There were 190, 118, and 168 children of Mennonite, indigenous and mixed race ethnicity, respectively. SE values between right/left eyes were nonsignificant. Mean visual acuity (VA without correction was better for Mennonites compared to indigenous or mixed race children (right eyes: 0.031, 0.090, and 0.102 logMAR units, respectively; P<0.000001. There were 2 cases of myopia in the Mennonite group (1.2% and 2 cases in the mixed race group (1.4% (SE ≤-0.5 D. The prevalence of hyperopia (SE ≥2 D was 40.6%, 34.2%, and 46.3% for Mennonite, indigenous and mixed race children. Corresponding astigmatism rates were 3.2%, 9.5%, and 12.7%. Females were slightly more hyperopic than males, and the 9-11 years age group was the most hyperopic. Mennonite and mixed race children were more hyperopic than indigenous children. CONCLUSIONS: Paraguayan children were remarkably hyperopic and relatively free of myopia. Differences with regard to gender, age, and ethnicity were small.

  18. Analysis of Feed for Digestibility Bali Cow in Group "Simantri" Program in Bali on Different Topographic

    Directory of Open Access Journals (Sweden)

    I Dewa Nyoman Sudita

    2015-01-01

    Full Text Available This study aims to determine the availability of feed ingredients, types and diversity as well as the proportion, relation to digestibility, VFA production and N-NH3 for Bali cow holding in the group "Simantri" program  in Bali on the different topography. Retrieving data using the method of observation at 27 group "Simantri", at 3 altitude / topography (lowland, medium and high. Variables measured: feed amount given, type and diversity of feed ingredients and proportions, sampling of feed materials, and take the liquid contents rumen. Sampling feed material to determine the nutrient content and digestibility of the ration, while knowing VFA rumen fluid contents (total and partial and N-NH3.  The results showed the higher the percentage of a natural grass in the lower ration. This condition causes the higher topography and diversity of the types of feed materials more and more.  The proportion of shrub legume Gliricidia leaves of trees, especially in the diet is relatively small (6.6%, while the potential of Gliricidia leaves pretty much at all altitude. Judging from the fulfillment of nutrients, Bali cow rations at all topographic meet the needs/head/day in the range of 6.10 to 8.14 kgDM, protein (CP ± of 750,2g  and energy ± 12 526 kcal ME.  In the test VFA rumen fluid obtained from 71.68 to 85.07 mMol in the category enough, while N-NH3: 5,21-6,11mMol still relatively low .  From this study we can conclude supply of feed for Bali cow in the group "Simantri" program in Bali nutrient content rations have to meet the needs.  The higher the proportion of legume shrub tree (Gliricidia leaves the digestibility, VFA production and N-NH3 getting better.

  19. Revisiting the modifiers: how should the evaluation and management of acute concussions differ in specific groups?

    Science.gov (United States)

    Makdissi, Michael; Davis, Gavin; Jordan, Barry; Patricios, Jon; Purcell, Laura; Putukian, Margot

    2013-04-01

    One of the key difficulties while managing concussion in sport is that there are few prognostic factors to reliably predict clinical outcome. The aims of the current paper are to review the evidence for concussion modifiers and to consider how the evaluation and management of concussion may differ in specific groups. A qualitative review of the literature on concussion was conducted with a focus on prognostic factors and specific groups including children, female athletes and elite versus non-elite players. PubMed, MEDLINE and SportsDiscus databases were reviewed. The literature demonstrates that number and severity of symptoms and previous concussions are associated with prolonged recovery and/or increased risk of complications. Brief loss of consciousness (LOC) and/or impact seizures do not reliably predict outcomes following a concussion, although a cautious approach should be adopted in an athlete with prolonged LOC or impact seizures (ie, >1 min). Children generally take longer to recover from concussions and assessment batteries have yet to be validated in the younger age group. Currently, there are insufficient data on the influence of genetics and gender on outcomes following a concussion. Several modifiers are associated with prolonged recovery or increased risk of complications following a concussion and have important implications for management. Children with concussion should be managed conservatively, with an emphasis on return to learn as well as return to sport. In cases of concussions managed with limited resources (eg, non-elite players), a conservative approach should also be taken. There should be an emphasis on concussion education in all sports and at all levels, particularly in junior and community-based competitions.

  20. Doing Anger Differently: two controlled trials of percussion group psychotherapy for adolescent reactive aggression.

    Science.gov (United States)

    Currie, Michael; Startup, Mike

    2012-08-01

    This study evaluates efficacy and effectiveness of 'Doing Anger Differently' (DAD), a group treatment for reactively aggressive 12-15 year old males. DAD uses percussion exercises to aid treatment. Study 1 compared a ten-week treatment with a waitlist control at pre, post and 6 month (treatment group only) follow-up. Study 2 replicated Study 1, but also followed up controls at 6 months. In study 1 (N = 54) the treatment resulted in lowered trait anger (Cohen's d = -1.3), aggression-reports (d = -1.0) and depression (d = -0.6), and increased self-esteem (d = 0.6), all maintained at six months. In study 2 (N = 65), aggression-reports fell to one fifth of pre-treatment levels at nine months follow-up (d = -1.2), with lowered trait anger (d = -0.4) and anger expression (d = -0.3) post-treatment.

  1. Reliability and group differences in quantitative cervicothoracic measures among individuals with and without chronic neck pain.

    Science.gov (United States)

    Shahidi, Bahar; Johnson, Cynthia L; Curran-Everett, Douglas; Maluf, Katrina S

    2012-10-31

    Clinicians frequently rely on subjective categorization of impairments in mobility, strength, and endurance for clinical decision-making; however, these assessments are often unreliable and lack sensitivity to change. The objective of this study was to determine the inter-rater reliability, minimum detectable change (MDC), and group differences in quantitative cervicothoracic measures for individuals with and without chronic neck pain (NP). Nineteen individuals with NP and 20 healthy controls participated in this case control study. Two physical therapists performed a 30-minute examination on separate days. A handheld dynamometer, gravity inclinometer, ruler, and stopwatch were used to quantify cervical range of motion (ROM), cervical muscle strength and endurance, and scapulothoracic muscle length and strength, respectively. Intraclass correlation coefficients for inter-rater reliability were significantly greater than zero for most impairment measures, with point estimates ranging from 0.45 to 0.93. The NP group exhibited reduced cervical ROM (P ≤ 0.012) and muscle strength (P ≤ 0.038) in most movement directions, reduced cervical extensor endurance (P = 0.029), and reduced rhomboid and middle trapezius muscle strength (P ≤ 0.049). Results demonstrate the feasibility of obtaining objective cervicothoracic impairment measures with acceptable inter-rater agreement across time. The clinical utility of these measures is supported by evidence of impaired mobility, strength, and endurance among patients with NP, with corresponding MDC values that can help establish benchmarks for clinically significant change.

  2. SMA carrier testing: a meta-analysis of differences in test performance by ethnic group.

    Science.gov (United States)

    MacDonald, William Kim; Hamilton, David; Kuhle, Stefan

    2014-12-01

    Spinal muscular atrophy (SMA) is a severe autosomal recessive genetic disease that occurs in about one in every 10 000 births. Prenatal carrier testing is available for SMA, and the utility of universal screening is actively debated. The aim of this study was to perform a systematic review and meta-analysis of SMA genotype frequency, carrier frequency, and carrier test performance in different ethnic groups. We performed a systematic review of the literature for studies on SMA carrier screening test performance. Ethnicity-specific allele frequencies, carrier rates, and screening test performance were determined from data of 169 000 individuals in 14 published studies. Pooled estimates were calculated for each ethnic group using a random effects meta-analysis. The detection rate of SMA screening in the non-Black population was 87-95%; however, detection rates fell to 71% among the Black population. These results highlight that although SMA carrier testing generally performs well and could be considered as a routine prenatal screen, SMA testing should be used cautiously in the Black population. © 2014 John Wiley & Sons, Ltd.

  3. Pathological gamblers and a non-psychiatric control group taking gender differences into account.

    Science.gov (United States)

    Echeburúa, Enrique; González-Ortega, Itxaso; de Corral, Paz; Polo-López, Rocío

    2013-01-01

    The current study aimed to identify personality traits, emotional states and adjustment variables in a sample of pathological gamblers as compared to a non-gambling control group taking gender differences into account. The sample for this study consisted of 206 subjects (103 pathological gamblers and 103 non-psychiatric subjects from the general population matched for age and gender). Pathological gamblers had a lower educational level and a family history of alcohol abuse higher than non-gamblers. In turn, female gamblers were affected by unemployment and a lower socioeconomic status more often than female non-gamblers. Pathological gamblers were more anxious and impulsive and suffered from a poorer self-esteem than non-gamblers. Likewise, pathological gamblers had a greater history of other Axis I psychiatric disorders and were more often affected by anxiety and depression symptoms and showed a more problematic adjustment to everyday life than non-gamblers. Alcohol abuse was not higher in pathological gamblers than in non-gamblers, but, when gender was taken into account, male gamblers were more affected by alcohol abuse than male non-gamblers. Importantly 68.6% of female gamblers versus 9.8% of control group women reported being victims of intimate partner violence. These findings can be used to specifically inform prevention and intervention efforts.

  4. Deoxynivalenol Exposure in Norway, Risk Assessments for Different Human Age Groups

    Science.gov (United States)

    Sundheim, Leif; Lillegaard, Inger Therese; Fæste, Christiane Kruse; Brantsæter, Anne-Lise; Brodal, Guro; Eriksen, Gunnar Sundstøl

    2017-01-01

    Deoxynivalenol (DON) is the most common mycotoxin in Norwegian cereals, and DON is detected in most samples of crude cereal grain and cereal food commodities such as flour, bran, and oat flakes. The Norwegian Scientific Committee for Food Safety assessed the risk for adverse effects of deoxynivalenol (DON) in different age groups of the domestic population. This review presents the main results from the risk assessment, supplemented with some recently published data. Impairment of the immune system together with reduced feed intake and weight gain are the critical effects of DON in experimental animals on which the current tolerable daily intake was established. Based on food consumption and occurrence data, the mean exposure to DON in years with low and high levels of DON in the flour, respectively, were in the range of or up to two times the Tolerable Daily Intake (TDI) in 1-year-old infants and 2-year-old children. In years with high mean DON concentration, the high (95th-percentile) exposure exceeded the TDI by up to 3.5 times in 1-, 2- , 4-, and 9-year-old children. The assessment concluded that exceeding the TDI in infants and children is of concern. The estimated dietary DON intakes in adolescent and adult populations are in the range of the TDI or below, and are not a health concern. Acute human exposure to DON is not of concern in any age group. PMID:28165414

  5. Reliability and group differences in quantitative cervicothoracic measures among individuals with and without chronic neck pain

    Directory of Open Access Journals (Sweden)

    Shahidi Bahar

    2012-10-01

    Full Text Available Abstract Background Clinicians frequently rely on subjective categorization of impairments in mobility, strength, and endurance for clinical decision-making; however, these assessments are often unreliable and lack sensitivity to change. The objective of this study was to determine the inter-rater reliability, minimum detectable change (MDC, and group differences in quantitative cervicothoracic measures for individuals with and without chronic neck pain (NP. Methods Nineteen individuals with NP and 20 healthy controls participated in this case control study. Two physical therapists performed a 30-minute examination on separate days. A handheld dynamometer, gravity inclinometer, ruler, and stopwatch were used to quantify cervical range of motion (ROM, cervical muscle strength and endurance, and scapulothoracic muscle length and strength, respectively. Results Intraclass correlation coefficients for inter-rater reliability were significantly greater than zero for most impairment measures, with point estimates ranging from 0.45 to 0.93. The NP group exhibited reduced cervical ROM (P ≤ 0.012 and muscle strength (P ≤ 0.038 in most movement directions, reduced cervical extensor endurance (P = 0.029, and reduced rhomboid and middle trapezius muscle strength (P ≤ 0.049. Conclusions Results demonstrate the feasibility of obtaining objective cervicothoracic impairment measures with acceptable inter-rater agreement across time. The clinical utility of these measures is supported by evidence of impaired mobility, strength, and endurance among patients with NP, with corresponding MDC values that can help establish benchmarks for clinically significant change.

  6. Effective Dose of Radon 222 Bottled Water in Different Age Groups Humans: Bandar Abbas City, Iran.

    Science.gov (United States)

    Fakhri, Yadolah; Mahvi, Amir Hossein; Langarizadeh, Ghazaleh; Zandsalimi, Yahya; Amirhajeloo, Leila Rasouli; Kargosha, Morteza; Moradi, Mahboobeh; Moradi, Bigard; Mirzaei, Maryam

    2015-06-04

    Radon 222 is a natural radioactive element with a half-life of 3.8 days. It is odorless and colorless as well as water-soluble. Consuming waters which contain high concentration of 222Rn would increase the effective dose received by different age groups. It would also be followed by an increased prevalence of cancer. In this research, 72 samples of the most commonly used bottled water in Bandar Abbas were collected in 3 consecutive months, May, June and July of 2013. Concentration 222Rn of was measured by radon-meter model RTM166-2. The effective dose received by the 4 age groups, male and female adults as well as children and infants was estimated using the equation proposed by UNSCEAR. The results revealed that the mean and range concentration of 222Rn in bottled waters were 641±9 Bq/m3 and 0-901 Bq/m3, respectively. The mean concentration of 222Rn in the well-known Marks followed this Zam Zam>Bishe>Koohrng>Dassani>Christal>Polour>Damavand>Sivan. Infants were observed to receive a higher effective dose than children. The highest and lowest effective dose received was found to belong to male adults and children, respectively.

  7. Relationship between physical attributes and heat stress in dairy cattle from different genetic groups

    Science.gov (United States)

    Alfonzo, Evelyn Priscila München; Barbosa da Silva, Marcos Vinicius Gualberto; dos Santos Daltro, Darlene; Stumpf, Marcelo Tempel; Dalcin, Vanessa Calderaro; Kolling, Giovani; Fischer, Vivian; McManus, Concepta Margaret

    2016-02-01

    Dairy cattle raised under harsh conditions have to adapt and prevent heat stress. The aim of this study was to evaluate physical characteristics and their association with heat tolerance in different genetic groups of dairy cattle. Thickness of the skin and coat, length and number of hairs, body measurements, as well as physiological parameters and body temperatures by infrared thermography were determined in 19 Holstein and 19 Girolando (½ and ¾ Holstein) cows. The Holstein cattle were less tolerant to heat stress than Girolando (GH50 and GH75 Holstein), because of the difficulty in dissipating heat due to the larger body size, as well as thicker and longer hairs. The correlations between physical characteristics, physiological parameters, and thermographic measurements prove to be inconsistent among genetic groups and therefore are not predictive of heat tolerance, while the regressions of morphometric characteristics on physiological and thermographic measures were not significant. Thus, the physical characteristics were not good predictors of physiological indices and thermographic temperature and so should not be used.

  8. Deoxynivalenol Exposure in Norway, Risk Assessments for Different Human Age Groups

    Directory of Open Access Journals (Sweden)

    Leif Sundheim

    2017-02-01

    Full Text Available Deoxynivalenol (DON is the most common mycotoxin in Norwegian cereals, and DON is detected in most samples of crude cereal grain and cereal food commodities such as flour, bran, and oat flakes. The Norwegian Scientific Committee for Food Safety assessed the risk for adverse effects of deoxynivalenol (DON in different age groups of the domestic population. This review presents the main results from the risk assessment, supplemented with some recently published data. Impairment of the immune system together with reduced feed intake and weight gain are the critical effects of DON in experimental animals on which the current tolerable daily intake was established. Based on food consumption and occurrence data, the mean exposure to DON in years with low and high levels of DON in the flour, respectively, were in the range of or up to two times the Tolerable Daily Intake (TDI in 1-year-old infants and 2-year-old children. In years with high mean DON concentration, the high (95th-percentile exposure exceeded the TDI by up to 3.5 times in 1-, 2- , 4-, and 9-year-old children. The assessment concluded that exceeding the TDI in infants and children is of concern. The estimated dietary DON intakes in adolescent and adult populations are in the range of the TDI or below, and are not a health concern. Acute human exposure to DON is not of concern in any age group.

  9. Different organochlorine contaminant profiles in groups of flounders (Platichthys flesus) from sampling locations around Denmark

    DEFF Research Database (Denmark)

    Vorkamp, Katrin; Svendsen, Tore Christian; Rønsholdt, Bent;

    2012-01-01

    Flounders (Platichthys flesus) from the waters around Denmark were analysed for their organochlorine (OC) profile to study whether fish from the same genetic population could be separated into characteristic subpopulations, based on their feeding grounds. The chemical analysis of fish liver...... provided a data set of 16 OC compounds in 94 samples from 2004 to 2006. Except for hexachlorocyclohexane, OC compounds were intercorrelated, indicating similar environmental fate and bioaccumulation. OC profiles are less affected than absolute concentrations by potentially confounding biological factors...... and thus more suitable for studies of intrapopulation differences in relation to feeding grounds. Principal component analysis grouped the samples according to locations. All but three of the 94 samples could be reclassified. Samples from the same and additional locations collected in 2003 provided...

  10. Strengthening resistance self-efficacy: influence of teaching approaches and gender on different consumption groups.

    Science.gov (United States)

    Heyne, Thomas; Bogner, Franz X

    2009-01-01

    Our study focused on strengthening the individual self-efficacy of low achieving 8th graders reducing drug-specific peer pressure through theoretical and practical training. The subject of the intervention was based on a substance-specific life skills program offering both teacher-centered and student-centered teaching approaches. A cluster analysis identified four consumption groups in our pre-test setting: (1) A "potentially curious" sample; (2) an "actually curious" sample; (3) an "experimenter" sample; and (4) a "consumer" sample. Self-efficacy was measured three times in a pre-, post-, and retention-test design. Only the "potentially curious" sub-sample showed higher resistance self-efficacy, boys and girls revealed no differences. Altogether, a short- and middle-term consistent increase was detected in both teaching methods. Consequences to increase the efficiency of drug prevention measurements are being discussed.

  11. A muscle stem cell for every muscle: variability of satellite cell biology among different muscle groups

    Directory of Open Access Journals (Sweden)

    Matthew Emerson Randolph

    2015-10-01

    Full Text Available The human body contains approximately 640 individual skeletal muscles. Despite the fact that all of these muscles are composed of striated muscle tissue, the biology of these muscles and their associated muscle stem cell populations are quite diverse. Skeletal muscles are affected differentially by various muscular dystrophies, such that certain genetic mutations specifically alter muscle function in only a subset of muscles. Additionally, defective muscle stem cells have been implicated in the pathology of some muscular dystrophies. The biology of muscle stem cells varies depending on their embryologic origins and the muscles with which they are associated. Here we review the biology of skeletal muscle stem cell populations of eight different muscle groups. Understanding the biological variation of skeletal muscles and their resident stem cells could provide valuable insight into mechanisms underlying the susceptibility of certain muscles to myopathic disease.

  12. Specific and unspecific gynecological alarm symptoms -prevalence estimates in different age groups

    DEFF Research Database (Denmark)

    Balasubramaniam, Kirubakaran; Ravn, Pernille; Larsen, Pia V;

    2015-01-01

    OBJECTIVE: To determine prevalence estimates of gynecological alarm symptoms in different age groups and to describe common patterns of gynecological symptoms. DESIGN: Web-based cross-sectional survey study. SETTING: Nationwide in Denmark. POPULATION: A random sample of 51 090 women aged 20 years...... guidelines. MAIN OUTCOME MEASURES: Prevalence estimates of self-reported experience of gynecological alarm symptoms within the preceding 4 weeks. RESULTS: A total of 26 466 women (54.5%) participated in the study. Some 80.3% had experienced at least one of the alarm symptoms within the preceding 4 weeks......: Gynecological alarm symptoms are frequent in the general population, mostly among younger women. Older women reported fewer symptoms, and they often appeared as single symptoms. This article is protected by copyright. All rights reserved....

  13. Assessment of acutely mentally ill patients' satisfaction of care: there is a difference among ethnic groups.

    Science.gov (United States)

    Anders, Robert L; Olson, Tom; Bader, Julia

    2007-03-01

    The relationship between quality of care and patient satisfaction has been documented. The specific research aim related to this study is to determine if differences exist among Caucasians, Asians, and Pacific Islanders who are hospitalized for an acute mental illness with regard to their perceived satisfaction with the care. The results of the overall study have been reported elsewhere. The sample was composed of 138 patients, of whom 34.7% were Caucasian, 31.2% Pacific Islanders, and 34.8% Asians. Within 24 hours of discharge, patients completed the Perceptions of Care instrument. Caucasians were over-represented in our sample in comparison to their percentage in the general population of Hawaii. These patients were significantly more satisfied (p = .04) with their care than the other ethnic groups. No single variable was found to specifically indicate why they were more satisfied than Pacific Islanders and Asians.

  14. GPU-acceleration of parallel unconditionally stable group explicit finite difference method

    CERN Document Server

    Parand, K; Hossayni, Sayyed A

    2013-01-01

    Graphics Processing Units (GPUs) are high performance co-processors originally intended to improve the use and quality of computer graphics applications. Since researchers and practitioners realized the potential of using GPU for general purpose, their application has been extended to other fields out of computer graphics scope. The main objective of this paper is to evaluate the impact of using GPU in solution of the transient diffusion type equation by parallel and stable group explicit finite difference method. To accomplish that, GPU and CPU-based (multi-core) approaches were developed. Moreover, we proposed an optimal synchronization arrangement for its implementation pseudo-code. Also, the interrelation of GPU parallel programming and initializing the algorithm variables was discussed, using numerical experiences. The GPU-approach results are faster than a much expensive parallel 8-thread CPU-based approach results. The GPU, used in this paper, is an ordinary laptop GPU (GT 335M) and is accessible for e...

  15. The Role of Family Influences on Adolescent Smoking in Different Racial/Ethnic Groups

    Science.gov (United States)

    Xiao, Yang; Gordon, Judith S.; Khoury, Jane C.

    2012-01-01

    Introduction: Although differing levels of family influences may explain some of the varying racial/ethnic trends in adolescent smoking behavior, clarification of which influences are protective against smoking may aid in the development of future ethnic-specific smoking prevention interventions. We sought to identify and compare the association of family influences on adolescent smoking among Black, Hispanic, and White adolescents in a cross-sectional national sample. Methods: Data from 6,426 parent–child dyads from Round 1 of the National Survey of Parents and Youth were analyzed. The association of family influences with ever-smokers and recent smokers was evaluated. Multinomial logistic regression using SUDAAN software was used. Results: While all measures of family influences except for parent–adolescent activities and intention to monitor were significantly protective against recent smoking and ever smoking among Whites, ethnic-specific family influence predictors of smoking were found in Blacks and Hispanics. Higher parental monitoring, higher intention to monitor, and higher connectedness were protective among Hispanics, while higher parental punishment and favorable attitude toward monitoring were protective against smoking among Blacks. For family influences significantly associated with protection against smoking, consistently greater protection was afforded against recent smoking than against ever smoking. Conclusions: Higher levels of family influences are protective against smoking among all racial/ethnic groups. There are consistencies in family influences on youth smoking; however, there may be specific family influences that should be differentially emphasized within racial/ethnic groups in order to protect against smoking behavior. Our results offer insight for designing strategies for preventing smoking in youth of different racial/ethnic backgrounds. PMID:22180584

  16. Bodily differences between Cold- and Heat-prescription groups in Sasang medicine

    Directory of Open Access Journals (Sweden)

    Young Joo Park

    2016-06-01

    Conclusion: In the SY-type men, the chest circumference was significantly greater in the Heat-prescription group compared to the Cold-prescription group. In the TE-type men, the rib-to-pelvic circumference ratio was significantly higher in the Heat-prescription group than in the Cold-prescription group.

  17. Stomatal cell wall composition: distinctive structural patterns associated with different phylogenetic groups.

    Science.gov (United States)

    Shtein, Ilana; Shelef, Yaniv; Marom, Ziv; Zelinger, Einat; Schwartz, Amnon; Popper, Zoë A; Bar-On, Benny; Harpaz-Saad, Smadar

    2017-04-01

    Stomatal morphology and function have remained largely conserved throughout ∼400 million years of plant evolution. However, plant cell wall composition has evolved and changed. Here stomatal cell wall composition was investigated in different vascular plant groups in attempt to understand their possible effect on stomatal function. A renewed look at stomatal cell walls was attempted utilizing digitalized polar microscopy, confocal microscopy, histology and a numerical finite-elements simulation. The six species of vascular plants chosen for this study cover a broad structural, ecophysiological and evolutionary spectrum: ferns ( Asplenium nidus and Platycerium bifurcatum ) and angiosperms ( Arabidopsis thaliana and Commelina erecta ) with kidney-shaped stomata, and grasses (angiosperms, family Poaceae) with dumbbell-shaped stomata ( Sorghum bicolor and Triticum aestivum ). Three distinct patterns of cellulose crystallinity in stomatal cell walls were observed: Type I (kidney-shaped stomata, ferns), Type II (kidney-shaped stomata, angiosperms) and Type III (dumbbell-shaped stomata, grasses). The different stomatal cell wall attributes investigated (cellulose crystallinity, pectins, lignin, phenolics) exhibited taxon-specific patterns, with reciprocal substitution of structural elements in the end-walls of kidney-shaped stomata. According to a numerical bio-mechanical model, the end walls of kidney-shaped stomata develop the highest stresses during opening. The data presented demonstrate for the first time the existence of distinct spatial patterns of varying cellulose crystallinity in guard cell walls. It is also highly intriguing that in angiosperms crystalline cellulose appears to have replaced lignin that occurs in the stomatal end-walls of ferns serving a similar wall strengthening function. Such taxon-specific spatial patterns of cell wall components could imply different biomechanical functions, which in turn could be a consequence of differences in

  18. Discussions and Suggestions on Dietary Survey of Key Population Group of Nuclear Facilities%核设施关键人群组膳食调查中若干问题的讨论与建议

    Institute of Scientific and Technical Information of China (English)

    谭承军; 熊小伟; 魏国良; 王韶伟; 商照荣

    2015-01-01

    通过对核设施关键人群组膳食调查方法局限性与现存问题的梳理,认为关键人群组膳食调查方法单一、调查内容不统一、关键人群组界定和认识有待于完善,提出如下建议:年龄组划分为婴儿(≤1岁)、儿童(2~6岁)、少年(7~17岁)和成人组(>17岁);膳食调查中粮食类细化到谷类、薯类和豆类,蔬菜至少细分为叶类和非叶类蔬菜;海产品细化到鱼类、甲壳类、软体类和藻类。在缺乏关键人群组食物消费量时,建议采用厂址半径5 km范围内膳食调查数据变化范围值的95%作为摄入率代替可能关键人群组的食物消费量。%By analyzing the dietary survey methods of key population groups of nuclear facilities, the paper argues that the current methods are too simple, the survey content is not consistent, and that the identification of key groups still need to be improved. The following suggestions are raised:the age groups are divided into infant (≤1 years), child (2~6 years old), teenager (7~17 years old) and adult group ( > 17 years);staple food are divided into frumentum, tubers and beans; vegetables are divided into leaf vegetables and non-leaf vegetables;and sea food are divided into fish, crustacean, mollusks and algae. In case of the absence of key groups’ diet amount data, it is suggested that 95% of the resulted amount range within 5 km of the facility is used.

  19. Explaining the link between objective and perceived differences in groups: The role of the belonging and distinctiveness motives.

    Science.gov (United States)

    Ormiston, Margaret E

    2016-02-01

    Group diversity research often focuses on objective diversity, or the actual compositional attributes of the group (e.g., differences in sex or functional background), and its impact on group processes and performance. More recently, diversity researchers have called for consideration of group members' perceptions of diversity, or their subjective understanding of differences within their group, because these perceptions have important effects on group outcomes. In fact, research has indicated only a modest correlation between objective and perceived diversity. Although the subjective nature of group diversity has important implications for group outcomes, we are still unclear about why and when perceived diversity diverges from objective diversity. In this article, I examine the role of identity motives, or motives that guide self-definition, in shaping member's perceptions of themselves and their group's composition. I argue that group members want to balance their needs for belonging and distinctiveness, but high levels of objective differences make them feel too distinct whereas low levels of objective differences makes them feel too deindividuated. Individual differences in the need to belong and be distinct further influence the degree to which these motives are satisfied. In turn, when these motives are unsatisfied, they will affect members' perceptions of differences. The presented theory helps to explain the discrepancy between objective differences and members' perceptions of differences, and ultimately helps integrate opposing findings in the diversity literature.

  20. Genetic and environmental contributions to population group differences on the Raven's Progressive Matrices estimated from twins reared together and apart

    OpenAIRE

    Rushton, J. Philippe; Bons, Trudy Ann; Vernon, Philip A; Čvorović, Jelena

    2007-01-01

    We carried out two studies to test the hypothesis that genetic and environmental influences explain population group differences in general mental ability just as they do individual differences within a group. We estimated the heritability and environmentality of scores on the diagrammatic puzzles of the Raven's Coloured and/or Standard Progressive Matrices (CPM/SPM) from two independent twin samples and correlated these estimates with group differences on the same items. In Study 1, 199 pair...

  1. Dissociative disorders and other psychopathological groups: exploring the differences through the Somatoform Dissociation Questionnaire (SDQ-20).

    Science.gov (United States)

    Amaral do Espirito Santo, Helena Maria; Pio-Abreu, José Luís

    2007-12-01

    The Somatoform Dissociation Questionnaire is a self-report questionnaire that has proven to be a reliable and valid instrument. The objectives of this study were to validate the Portuguese version and to determine its capability to distinguish patients with dissociative disorders from others with psychopathological disorders. 234 patients answered the translated version of Somatoform Dissociation Questionnaire. The Portuguese Dissociative Disorders Interview Schedule was used to validate clinical diagnosis. Patients with dissociative disorder (n = 113) were compared to a control group of 121 patients with various anxiety and depression disorders. Reliability measured by Cronbach's a was 0.88. The best performance of the Portuguese form was at a cut-off point of 35, which distinguishes between dissociative disorder and neurotic disorders with a good diagnostic efficacy (sensitivity = 0.73). The somatoform dissociation was significantly more frequent in dissociative disorder patients, conversion disorder patients and post-traumatic stress disorder patients. These findings suggest that dissociative disorders can be differentiated from other psychiatric disorders through somatoform dissociation. The Portuguese version of the Somatoform Dissociation Questionnaire has fine psychometric features that sustain its cross-cultural validity.

  2. Welfare Balance of Different Interest Groups During Rural-urban Land Conversion

    Institute of Scientific and Technical Information of China (English)

    Peng Kaili; Zhang Peng; Zhang Anlu

    2009-01-01

    Rural-urban land conversion is currently a common social economic phenomenon during the process of economic development and rural urbanization in China.Rural-urban land conversion is positively effective as far as social and economic benefits are concerned (Yang,2002),but its negative effect is also evident,resulting in such problems as low efficiency of rural land configuration and loss of social welfare.Consequently,farmers should also have an equal chance to enjoy the social welfare enhanced by land conversion.Based on the theories of welfare economy,this paper puts forward policy suggestions by discussing the welfare changes of various interest groups,builds the model of welfare distribution,and analyzes the conditions of maximizing social welfare.The absolute and opposite value of social welfare is closely related with the speed of rural-urban land conversion,and governments should give farmers and collectives fair compensation to make up for the utility loss caused by land expropriation,which are conclusions drawn from this paper.This study aims to provide a theoretical basis for regulating targets and evaluation criteria,realizing the mechanism and implementation of public polices during rural-urban land conversion.

  3. High-fidelity simulation among bachelor students in simulation groups and use of different roles.

    Science.gov (United States)

    Thidemann, Inger-Johanne; Söderhamn, Olle

    2013-12-01

    Cost limitations might challenge the use of high-fidelity simulation as a teaching-learning method. This article presents the results of a Norwegian project including two simulation studies in which simulation teaching and learning were studied among students in the second year of a three-year bachelor nursing programme. The students were organised into small simulation groups with different roles; nurse, physician, family member and observer. Based on experiences in different roles, the students evaluated the simulation design characteristics and educational practices used in the simulation. In addition, three simulation outcomes were measured; knowledge (learning), Student Satisfaction and Self-confidence in Learning. The simulation was evaluated to be a valuable teaching-learning method to develop professional understanding and insight independent of roles. Overall, the students rated the Student Satisfaction and Self-confidence in Learning as high. Knowledge about the specific patient focus increased after the simulation activity. Students can develop practical, communication and collaboration skills, through experiencing the nurse's role. Assuming the observer role, students have the potential for vicarious learning, which could increase the learning value. Both methods of learning (practical experience or vicarious learning) may bridge the gap between theory and practice and contribute to the development of skills in reflective and critical thinking.

  4. Pharmacotherapeutic directions of iodine herbal remedies use for different groups of thyroid deseases treatment

    Directory of Open Access Journals (Sweden)

    Інна Миколаївна Владимирова

    2015-11-01

    Full Text Available Recently, the increase of endocrine diseases is observed worldwide. Diabetes mellitus and thyroid gland pathologies are the most widespread. Endocrine diseases can be acute or chronic. In some cases, they are life threatening.There are different reasons of thyroid gland pathologies development. Both poor nutrition and poor quality water use, and unfavorable environmental conditions, including radiation, are among them. Iodine deficiency is determined to be one of the main reasons of these diseases.Aim. Determination of the pharmacotherapeutic directions of iodine herbal remedies use for different groups of thyroid diseases treatment.Methods. Thyroid stimulating action determination (primary screening and model pathology has been carried out by the method of “goiter reaction” in rats at the Central Scientific-Research Laboratory of National University of Pharmacy. Determination of thyroid hormone blood level in rats has been carried out at the Laboratory of Radioactive Endocrinology of the State Institution “Grigoriev Institute for medical Radiology NAMS of Ukraine”.Results. According to the research results generalization, correctness of developed algorithms was confirmed; peculiarities of the influence on pathological processes in thyroid, and prospects of implementation and use of herbs and herbal remedies for thyroid diseases prevention and treatment were determined.Conclusion. Obtained experimental data are actual for the modern medicine, and new scientific research, specifying their place in etiology, pathogenesis and peculiarities of clinical course of many diseases, will improve the efficiency of treatment and prevention of thyroid diseases

  5. Constraining anisotropy of the universe from different groups of type-Ia supernovae

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Zhe; Li, Xin [Chinese Academy of Sciences, Institute of High Energy Physics, Beijing (China); Chinese Academy of Sciences, Theoretical Physics Center for Science Facilities, Beijing (China); Lin, Hai-Nan; Wang, Sai [Chinese Academy of Sciences, Institute of High Energy Physics, Beijing (China)

    2014-03-15

    Recently released Planck data and other astronomical observations show that the universe may be anisotropic on large scales. Inspired by this, anisotropic cosmological models have been proposed. We note that the Finsler-Randers spacetime provides an appropriate framework for the anisotropic cosmology. By adding an arbitrary 1-form to the Friedmann-Robertson-Walker line element, a privileged axis in the universe is picked out. The distance-redshift relation is modified to be direction-dependent. We wish that the anisotropic cosmological model may be tested crossly by independent observations. Type-Ia supernovae (SNe Ia) calibrated from four different light curve fitters are used to constrain the possible anisotropy of the universe. The magnitudes of anisotropy are all between 2-5 %, but the systematic uncertainty cannot be excluded. The directions of the privileged axis seem to differ from each other. The statistical significance is not high enough to make a convincing conclusion. Nevertheless, the 1σ contours in the (l,b) plane obtained from four groups of SNe Ia have an overlap, centering at (l,b) ∼ (170 , 0 ). Monte Carlo simulation shows that the anisotropy is unlikely to be caused by the selection effect. (orig.)

  6. Management in non-traumatic arm, neck and shoulder complaints: differences between diagnostic groups.

    Science.gov (United States)

    Feleus, Anita; Bierma-Zeinstra, Sita M A; Miedema, Harald S; Verhaar, Jan A N; Koes, Bart W

    2008-09-01

    Arm, neck and/or shoulder complaints are common in western societies. In the Netherlands, general practice guidelines are issued on shoulder pain and epicondylitis only. Little is known about actual management of the total range of diagnoses. The objectives of the study are: to determine management in patients consulting the GP with a new episode of non-traumatic arm neck and shoulder complaints up to 6 months after the first consultation. To evaluate differences in management between patients with specific diagnoses versus non-specific diagnoses and between specific diagnostic groups. In a prospective cohort study in general practice. We recruited 682 eligible patients. Data on diagnosis, management, patient- and complaint-characteristics were collected. Co-occurrence of treatment options was presented in scaled rectangles. After 6 months, additional diagnostic tests had been performed in 18% of the patients, mainly radiographic examination (14%). Further, 49% had been referred for physiotherapy and 12% to the medical specialist. Patients with specific diagnoses were more frequently referred for specialist treatment, and patients with non-specific diagnoses for physiotherapy. Corticosteroid injections (17%) were mainly applied specific diagnoses (e.g. impingement syndrome, frozen shoulder, carpal tunnel and M. Quervain). Frequencies of prescribed medication (51%) did not differ between specific and non-specific diagnoses. In 19% of the patients no referral, prescribed analgesics or injection was applied. Braces (4%) were mainly prescribed in epicondylitis. Overall, management most frequently consisted of prescribed analgesics and referral for physiotherapy. Specific and non-specific diagnostic subgroups differed in the frequency corticosteroid injections were applied, and referrals to physiotherapy and to a medical specialist.

  7. Influenza C virus high seroprevalence rates observed in 3 different population groups.

    Science.gov (United States)

    Salez, Nicolas; Mélade, Julien; Pascalis, Hervé; Aherfi, Sarah; Dellagi, Koussay; Charrel, Rémi N; Carrat, Fabrice; de Lamballerie, Xavier

    2014-08-01

    The epidemiology of Influenza C virus (FLUCV) infections remains poorly characterised. Here, we have examined the age- and location-specific seroprevalence of antibodies against FLUCV in 1441 sera from metropolitan continental France (Marseille), South-West Indian Ocean French territories (Reunion Island) and United-Kingdom (Edinburgh) using a combination of haemagglutination inhibition, virus neutralisation and ELISA assays. Our results show that immunity to FLUCV is common in all locations studied (global seroprevalence values >50%) and that the first immunising contacts generally occur early in life (i.e., in the 0-4 year-old age group). The latter item is further supported by the detection of FLUCV RNA by RT-PCR in naso-pharyngeal samples collected in patient attending the Emergency Room of the Public hospitals of Marseille, France with a large majority of children under 10 years-old: 17 (60.7%) in children ≤3 yo, 10 (35.7%) in the 4-10 yo age group and 1 (3.6%) in an adult (49yo). The temporal distribution of cases was atypical with regard to influenza (a large proportion of cases occurred in spring and summer) and the clinical presentation was diverse, including but being not limited to classical Influenza-like-Ilnesses. Altogether, our results indicate an intense circulation of FLUCV in the different study areas and an early occurrence of infection in human life. Flu C appears to be a widely under-diagnosed and under-studied human paediatric disease that obviously deserves further clinical and epidemiological characterisation. Copyright © 2014 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

  8. Appearances can be deceptive: different diversification patterns within a group of Mediterranean earthworms (Oligochaeta, Hormogastridae).

    Science.gov (United States)

    Novo, Marta; Almodóvar, Ana; Fernández, Rosa; Trigo, Dolores; Díaz-Cosín, Darío J; Giribet, Gonzalo

    2012-08-01

    Many recent studies on invertebrates have shown how morphology not always captures the true diversity of taxa, with cryptic speciation often being discussed in this context. Here, we show how diversification patterns can be very different in two clades of closely related earthworms in the genus Hormogaster stressing the risk of using nonspecific substitution rate values across taxa. On the one hand, the Hormogaster elisae species complex, endemic to the central Iberian Peninsula, shows morphological stasis. On the other hand, a clade of Hormogaster from the NE Iberian Peninsula shows an enormous morphological variability, with 15 described morphospecies. The H. elisae complex, however, evolves faster genetically, and this could be explained by the harsher environmental conditions to which it is confined-as detected in this study, that is, sandier and slightly poorer soils with lower pH values than those of the other species in the family. These extreme conditions could be at the same time limiting morphological evolution and thus be responsible for the observed morphological stasis in this clade. Contrarily, Hormogaster species from the NE Iberian Peninsula, although still inhabiting harsher milieu than other earthworm groups, have had the opportunity to evolve into a greater morphological disparity. An attempt to delimit species within this group following the recently proposed general mixed Yule-coalescent method showed a higher number of entities than expected under the morphospecies concept, most probably due to the low vagility of these animals, which considerably limits gene flow between distant conspecific populations, but also because of the decoupling between morphological and genetic evolution in the H. elisae complex. © 2012 Blackwell Publishing Ltd.

  9. Patterns of Adverse Drug Reactions in Different Age Groups: Analysis of Spontaneous Reports by Community Pharmacists.

    Directory of Open Access Journals (Sweden)

    Yun Mi Yu

    Full Text Available To evaluate the clinical manifestations and causative drugs associated with adverse drug reactions (ADRs spontaneously reported by community pharmacists and to compare the ADRs by age.ADRs reported to the Regional Pharmacovigilance Center of the Korean Pharmaceutical Association by community pharmacists from January 2013 to June 2014 were included. Causality was assessed using the WHO-Uppsala Monitoring Centre system. The patient population was classified into three age groups. We analyzed 31,398 (74.9% ADRs from 9,705 patients, identified as having a causal relationship, from a total pool of 41,930 ADRs from 9,873 patients. Median patient age was 58.0 years; 66.9% were female.Gastrointestinal system (34.4%, nervous system (14.4%, and psychiatric (12.1% disorders were the most frequent symptoms. Prevalent causative drugs were those for acid-related disorders (11.4%, anti-inflammatory products (10.5%, analgesics (7.2%, and antibacterials (7.1%. Comparisons by age revealed diarrhea and antibacterials to be most commonly associated with ADRs in children (p < 0.001, whereas dizziness was prevalent in the elderly (p < 0.001. Anaphylactic reaction was the most frequent serious event (19.7%, mainly associated with cephalosporins and non-steroidal anti-inflammatory drugs. Among 612 ADRs caused by nonprescription drugs, the leading symptoms and causative drugs were skin disorders (29.6% and non-steroidal anti-inflammatory drugs (16.2%, respectively.According to the community pharmacist reports, the leading clinical manifestations and causative drugs associated with ADRs in outpatients differed among age groups.

  10. Group Differences in Student Performance in the Selection to Higher Education: Tests vs Grades

    Directory of Open Access Journals (Sweden)

    Christina Wikström

    2017-08-01

    Full Text Available Student selection in the Swedish admission to higher education system is based on two fundamentally different performance measures: their criterion-referenced upper secondary grade point average (GPA and their score on a norm-referenced and multiple-choice admissions test [Swedish admissions test (SweSAT]. Several student characteristics are known to affect rankings in such assessments. The objectives of this study are to assess main and interactive effects of several variables that influence rankings obtained from these measures in greater detail than previously attempted and assess the findings from a fairness perspective. The data consist of test scores, upper secondary grades, and background information for SweSAT participants aged 19–25 years, who took the test in the autumn of 2011 (N = 23,214 or spring of 2012 (N = 27,075. The data were analyzed through correlation and regression analyses. The results support previous findings that gender, parents’ education, and immigration status are all influential. Males obtain better SweSAT scores than females, while females obtain better GPAs, in accordance with previous findings regarding gender-related variations in rankings provided by similar instruments. Moreover, we found the same pattern in scores for specific components of the test and grades in specific subjects, suggesting that the test and GPA measure different, gender-related, things. In addition, students with an immigrant background seem to be more highly ranked by grades than by the SweSAT, largely due to differences in assessments of their verbal skills.

  11. Species groups occupying different trophic levels respond differently to the invasion of semi-natural vegetation by Solidago canadensis

    NARCIS (Netherlands)

    Groot, de M.; Kleijn, D.; Jogan, N.

    2007-01-01

    We studied the impact of the invasive plant species Solidago canadensis on the species richness of vascular plants and the abundance, species richness and diversity of butterflies, hoverflies and carabid beetles in herbaceous semi-natural habitats near Ljubljana, Slovenia. The species groups were sa

  12. Intrapartum caesarean rates differ significantly between ethnic groups--relationship to induction.

    LENUS (Irish Health Repository)

    Ismail, Khadijah I

    2012-01-31

    OBJECTIVE: Given international variation in obstetric practices and outcomes, comparison of labour outcomes in different ethnic groups could provide important information regarding the underlying reasons for rising caesarean delivery rates. Increasing numbers of women from Eastern European countries are now delivering in Irish maternity hospitals. We compared labour outcomes between Irish and Eastern European (EE) women in a large tertiary referral center. STUDY DESIGN: This was a prospective consecutive cohort study encompassing a single calendar year. The cohort comprised 5550 Irish and 867 EE women delivered in a single institution in 2009. Women who had multiple pregnancies, breech presentation, and elective or pre-labour caesarean sections (CS) were excluded. Data obtained from birth registers included maternal age, nationality, parity, gestation, onset of labour, mode of delivery and birth weight. RESULTS: The overall intrapartum CS rate was 11.4% and was significantly higher in Irish compared to EE women (11.8% vs. 8.8%; p=0.008). The proportion of primiparas was lower in Irish compared to EE women (44.8% vs. 63.6%; p<0.0001). The intrapartum CS rate was almost doubled in Irish compared to EE primiparas (20.7% vs. 11.0%; p<0.0001). Analysis of primiparas according to labour onset revealed a higher intrapartum CS rate in Irish primiparas in both spontaneous (13.5% vs. 7.2%; p<0.0001) and induced labour (29.5% vs. 19.3%; p=0.005). Irish women were older with 19.7% of primiparas aged more than 35, compared to 1.6% of EE women (p<0.0001). The primigravid CS rate in Irish women was significantly higher in women aged 35 years or older compared women aged less than 35 (30.6% vs. 18.3%; p<0.0001) consistent in both spontaneous and induced labour. The primiparous induction rate was 45.4% in Irish women compared to 32% in EE women, and more Irish women were induced before 41 weeks gestation. CONCLUSION: The results highlight that primigravid intrapartum CS rates were

  13. Self-Reported Differences in Empowerment Between Lurkers and Posters in Online Patient Support Groups

    NARCIS (Netherlands)

    Uden-Kraan, van Cornelia F.; Drossaert, Constance H.C.; Taal, Erik; Seydel, Erwin R.; Laar, van de Mart A.F.J.

    2008-01-01

    Background: Patients who visit online support groups benefit in various ways. Results of our earlier study indicated that participation in online support groups had a profound effect on the participants’ feelings of “being empowered.” However, most studies of online patient support groups have focus

  14. Group Differences between English and Spanish Speakers' Reading Fluency Growth in Bilingual Immersion Education

    Science.gov (United States)

    Taub, Gordon E.; Sivo, Stephen A.; Puyana, Olivia E.

    2017-01-01

    This study investigates second language acquisition of learners enrolled in a dual language/two-way bilingual immersion program. Two groups of third-grade students participated in this study. The first group was composed of Spanish-dominant participants learning English, and the second group was composed of English-dominant students learning…

  15. Stability Parameters for Grain Yield and its Component Traits in Maize Hybrids of Different FAO Maturity Groups

    Directory of Open Access Journals (Sweden)

    Dragan Djurovic

    2014-12-01

    Full Text Available An objective evaluation of maize hybrids in intensive cropping systems requires identification not only of yield components and other agronomically important traits but also of stability parameters. Grain yield and its components were assessed in 11 maize hybrids with different lengths of growing season (FAO 300-700 maturity groups using analysis of variance and regression analysis at three different locations in Western Serbia. The test hybrids and locations showed significant differences in grain yield, grain moisture content at maturity, 1,000-kernel weight and ear length. A significant interaction was observed between all traits and the environment. The hybrids with higher mean values of the traits, regardless of maturity group, generally exhibited sensitivity i.e. adaptation to more favourable environmental conditions as compared to those having lower mean values. Regression coefficient (bi values for grain yield mostly suggested no significant differences relative to the mean. The medium-season hybrid gave high yields and less favourable values of stability parameters at most locations and in most years, as compared to mediumlate hybrids. As compared to medium-early hybrids, medium-late hybrids (FAO 600 and 700 mostly exhibited unfavourable values of stability parameters i.e. a specific response and better adaptation to favourable environmental conditions, and gave higher average yields. Apart from producing lower average yields, FAO 300 and 400 hybrids showed higher yield stability as compared to the other hybrids tested. Medium-late hybrids had higher yields and showed a better response to favourable environmental conditions compared to early-maturing hybrids. Therefore, they can be recommended for intensive cultural practices and low-stress environments. Due to their more favourable stability parameter values, medium-early hybrids can be recommended for low-intensity cultural practices and stressful environments.

  16. δ13 and water-use efficiency indicated by δ13 of different plant functional groups on Changbai Mountains, Northeast China

    Institute of Scientific and Technical Information of China (English)

    TAN WenBing; WANG GuoAn; HAN JiaMao; LIU Min; ZHOU LiPing; LUO Ting; CAO ZiYu; CHENG ShuZhi

    2009-01-01

    Leaf δ13 of different plant functional groups (trees, shrubs and forbs; evergreen and deciduous; an-nual, biennial and perennial) were examined on the Changbai Mountains, China. Life form has a sig-nificant influence on plant δ13, suggesting that leaf δ13 is also ideal for distinguishing functional groups species in temperate and frigid zones with high humidity. Additionally, the difference of wa-ter-use efficiency (WUE) is significant among different plant functional groups.δ13 and WUE are in the following order of forbs biennial herbs > perennial herbs, not in accor-dance with the pattern obtained by previous studies in deserts, suggesting that the ranking of δ13 and WUE among annual, biennial and perennial herbs may be dependent on local water availability.

  17. Integrated Analysis and Visualization of Group Differences in Structural and Functional Brain Connectivity: Applications in Typical Ageing and Schizophrenia

    OpenAIRE

    Langen, Carolyn D.; Tonya White; Arfan Ikram, M.; Vernooij, Meike W.; Niessen, Wiro J.

    2015-01-01

    Structural and functional brain connectivity are increasingly used to identify and analyze group differences in studies of brain disease. This study presents methods to analyze uni- and bi-modal brain connectivity and evaluate their ability to identify differences. Novel visualizations of significantly different connections comparing multiple metrics are presented. On the global level, "bi-modal comparison plots" show the distribution of uni- and bi-modal group differences and the relationshi...

  18. Prevalence of visual impairment and refractive errors among different ethnic groups in schoolchildren in Turpan, China.

    Science.gov (United States)

    Chin, Man Pan; Siong, Kar Ho; Chan, Ka Ho; Do, Chi Wai; Chan, Henry Ho Lung; Cheong, Allen Ming Yan

    2015-05-01

    There is currently limited information about ethnic differences in myopia prevalence within mainland China, especially in rural or semi-rural areas. We examined the prevalence of refractive errors, visual impairment and spectacle coverage in school children of varying ethnicity in Turpan, Xinjiang province. A community eye care service was provided for five schools. Presenting monocular distance and near visual acuity (VA), and ocular alignment were assessed. Retinoscopy and cycloplegic subjective refraction were performed for participants with presenting visual impairment (distance VA worse than 0.3 logMAR; Snellen 6/12 or 20/40) or abnormal binocular vision. Questionnaires administered prior to the eye examinations were used to collect information regarding personal lifestyle and parental myopia. A total of 646 out of 690 (94%) subjects aged four to 19 years (11.9 ± 2.6; mean ± S.D.) completed the eye examination. Three hundred and eighty-two (59%) of participants were of Uyghur ethnicity, followed by Han, 176 (27%) and Hui, 74 (12%). The mean age of Uyghur, Han and Hui students was 12.3 ± 2.7, 11.4 ± 2.6 and 11.4 ± 2.3 years respectively, in which the Uyghur students were significantly older than the Han and Hui students (F(3,631) = 5.58 p visual impairment was not significantly different among the ethnic groups (p = 0.26). After cycloplegic refraction, most subjects' VA (98%) improved to better than 0.3 logMAR (Snellen 6/12 or 20/40). The prevalence of "clinically-significant myopia" (≤-0.50 dioptres) was 27%, 18% and 13% in Han, Hui and Uyghur children, respectively (p Hui > Uyghur). As reported previously, uncorrected/under-corrected refractive error was the main cause of presenting visual impairment. © 2015 The Authors Ophthalmic & Physiological Optics © 2015 The College of Optometrists.

  19. Comparison of different sampling techniques and of different culture methods for detection of group B streptococcus carriage in pregnant women

    OpenAIRE

    Verhelst Rita; Temmerman Marleen; Verstraelen Hans; Cools Piet; Saerens Bart; Claeys Geert; Tency Inge; El Aila Nabil A; Vaneechoutte Mario

    2010-01-01

    Abstract Background Streptococcus agalactiae (group B streptococcus; GBS) is a significant cause of perinatal and neonatal infections worldwide. To detect GBS colonization in pregnant women, the CDC recommends isolation of the bacterium from vaginal and anorectal swab samples by growth in a selective enrichment medium, such as Lim broth (Todd-Hewitt broth supplemented with selective antibiotics), followed by subculture on sheep blood agar. However, this procedure may require 48 h to complete....

  20. Lending Groups and Different Social Capitals in Developed and Developing Countries

    Directory of Open Access Journals (Sweden)

    Diego A. B. Marconatto

    2016-11-01

    Full Text Available Lending groups (LGs and social capital are two central elements to the many microfinance solutions operating around the world. However, LG effectiveness in reducing transaction costs and lending risks for microfinance institutions (MFIs is mediated by institutional environments. Starting from this assumption, we discuss the existent interactions between the institutional environments of developed (Anglo-Saxon and communitarian and developing countries with different stocks of social capital (individual, network and institutional and the influences of this interaction on LG effectiveness. In order to do so, we applied the institutional perspective of O. Williamson to build a theoretical framework to examine the interaction of all these conditions, allowing for analysis of their main relations within the microfinance context. Based on this framework, we propose on the one hand that in developing and Anglo-Saxon developed nations, stocks of both individual and network social capital are the most important for an LG’s effectiveness. However, in Anglo-Saxon countries, these two stocks of social capital are complemented by formal contracting devices. In communitarian developed countries, on the other hand, the stocks of institutional social capital have a stronger positive impact on LG dynamics.

  1. Detecting the Subtle Shape Differences in Hemodynamic Responses at the Group Level

    Directory of Open Access Journals (Sweden)

    Gang eChen

    2015-10-01

    Full Text Available The nature of the hemodynamic response (HDR is still not fully understood due to the multifaceted processes involved. Aside from the overall amplitude, the response may vary across cognitive states, tasks, brain regions, and subjects with respect to characteristics such as rise and fall speed, peak duration, undershoot shape, and overall duration. Here we demonstrate that the fixed-shape or adjusted-shape methods may fail to detect some shape subtleties. In contrast, the estimated-shape method (ESM through multiple basis functions can provide the opportunity to identify some subtle shape differences and achieve higher statistical power at both individual and group levels. Previously, some dimension reduction approaches focused on the peak magnitude, or made inferences based on the area under the curve or interaction, which can lead to potential misidentifications. By adopting a generic framework of multivariate modeling (MVM, we showcase a hybrid approach that is validated by simulations and real data. Unlike the few analyses that were limited to main effect, two- or three-way interactions, we extend the approach to an inclusive platform that is more adaptable than the conventional GLM, achieving a practical equipoise among representation, false positive control, statistical power, and modeling flexibility.

  2. ENDOGENOUS INTOXICATION IN ANIMALS OF DIFFERENT AGE GROUPS IN CASE OF POLYTRAUMA

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    S. R. Pidruchna

    2017-02-01

    Full Text Available Background.  Associated injury is a worldwide social and economic problem. Age related aspects of endogenous intoxication are not studied comprehensively. Annually, from 44 000 to 65 000 citizens die because of traumatic injuries. As a result, this number increased by 32.6% for the last 10 years.     The detoxification system, as a component of the functional systems of the organism, experiences significant changes in case of polytrauma. Objective. The study was aimed to discover pathogenetic peculiarities of the multiple trauma in age aspect in different disease periods and to explore the level of endogenous intoxication in this condition. Methods. The experiments were performed on 72 white male rats aged 3, 6 and 12 months, which underwent simulation of severe skeletal trauma and examination of the contents of middle mass molecules and endogenous intoxication index (markers of endogenous intoxication in 1, 4 and 24 hours after the associated injury. Results. The most significant increase of the middle mass molecules was fixed in 24 hours after modeling of severe skeletal injuries in all groups of animals, especially it was the most pronounced in 12-month-old animals. The erythrocyte intoxication index reached the highest level in 4 hours after the injury, its increase was most significant in sexually mature adult animals. Conclusion. A significant increasing of endogenous intoxication markers in 12-month-old rats, if compared to 3- and 6-month-old animals, can be caused by the decrease in compensatory protection mechanisms.

  3. [Comparative characteristics of antioxidant status in women with diabetes type 2 of different age groups].

    Science.gov (United States)

    Ishonina, O G; Mikashinovich, Z I; Olempieva, E V; Kovalenko, T D

    2011-01-01

    The purpose of this study was to evaluate the metabolic processes in women with diabetes mellitus type 2 of different age groups. It is established that hyperglycemia in aged women is characterized by the development of pronounced oxidative stress, which is the result of changes in the primary structure of protein molecules due to non enzymatic glycosylation of amino acid residues in the active sites. It is known that observed depletion of reduced glutathione pool is associated with high risk of genotoxicity, because it correlates with activation of mitochondrial, chromatin dysfunction and fragmentation of the DNA. In addition, hydroperoxides of polyunsaturated fatty acids formation leads to necrosis and apoptosis. It can be assumed that the diabetes mellitus type 2 triggers processes of apoptosis, which leads to the activation of aging programs and increase the mortality of patients. Obviously, the change in the concentration of thiol antioxidants, as well as the change in concentration of LPO molecular products may be one of the criteria for evaluation of aging and the efficiency of the treatment of patients.

  4. Antioxidant and haematological biomarkers in different groups of horses supplemented with polyunsaturated oil and vitamin E.

    Science.gov (United States)

    Mélo, S K M; Diniz, A I A; de Lira, V L; de Oliveira Muniz, S K; da Silva, G R; Manso, H E C da C C; Manso Filho, H C

    2016-10-01

    Oxidative stress has been correlated with pathologies that impair the performance of athlete horses. The aim of this study was to assess the effects of supplementation with a mixture of polyunsaturated oil and vitamin E on the antioxidant and haematological biomarkers of horses. Horses under maintenance care (n = 6) and horses in training (n = 10) received 100 and 300 ml of the oil mixture respectively. Supplementation was provided for a period of 8 weeks, together with isocaloric inclusion. Blood samples were collected at three time periods (pretest, after 4 weeks and after 8 weeks) to analyse the following: the red blood cell count (RBCc); haemoglobin (Hb); haematocrit (HT); leucocytes; lymphocytes; platelets; the mean corpuscular volume (MCV); the mean corpuscular haemoglobin concentration (MCHC); the standard deviation of the red blood cell distribution width (RDW-SD); the coefficient of variation of the red blood cell distribution width (RDW-CV); glutathione peroxidase (GPx); superoxide dismutase (SOD); uric acid (UrAc); total plasma proteins (TPP); and creatine kinase (CK). After the 8 weeks of supplementation, animals under maintenance care exhibited significant increases in SOD, UrAc, the white blood cell count (WBCc), the RDW-SD and the RDW-CV (p supplementation with polyunsaturated oil and vitamin E increases blood antioxidants among animals under maintenance and in training, with different trends, while contributing to the fight against oxidative stress in each group analysed.

  5. Size of government and entrepreneurship. Analysis of three groups of countries with different economic development

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    Juan Carlos Díaz Casero

    2015-07-01

    Full Text Available This study analyzes the impact of the "size of government" in entrepreneurial activity for countries with different levels of economical development. It has been used the variables "size of government" of the economic freedom indices released by the Economic Freedom Network (2000-2009 and by The Heritage Foundation (2000-2011, and the variables of "entrepreneurship" released by the Global Entrepreneurship Monitor. Furthermore, the same analysis has been carried out grouping the countries by development level, following the classification elaborated by the World Economic Forum. Statistical analyses of correlations have shown that the “size of government” is related to entrepreneurship. The variables "Size of Government: Expenditures, Taxes and Enterprises" and " Government Size” have revealed a positive correlation with the total, opportunity and necessity entrepreneurial activity indices for the economies based on efficiency and innovation, thus less taxes on income and lower government spending, increase the entrepreneurship of the country. In “factor driven economies”, there is no relationship between the size of government and entrepreneurship

  6. Young and older emotional faces: are there age group differences in expression identification and memory?

    Science.gov (United States)

    Ebner, Natalie C; Johnson, Marcia K

    2009-06-01

    Studies have found that older compared with young adults are less able to identify facial expressions and have worse memory for negative than for positive faces, but those studies have used only young faces. Studies finding that both age groups are more accurate at recognizing faces of their own than other ages have used mostly neutral faces. Thus, age differences in processing faces may not extend to older faces, and preferential memory for own age faces may not extend to emotional faces. To investigate these possibilities, young and older participants viewed young and older faces presented either with happy, angry, or neutral expressions; participants identified the expressions displayed and then completed a surprise face recognition task. Older compared with young participants were less able to identify expressions of angry young and older faces and (based on participants' categorizations) remembered angry faces less well than happy faces. There was no evidence of an own age bias in memory, but self-reported frequency of contact with young and older adults and awareness of own emotions played a role in expression identification of and memory for young and older faces.

  7. Clinical validation of different echocardiographic motion pictures expert group-4 algorythms and compression levels for telemedicine.

    Science.gov (United States)

    Barbier, Paolo; Alimento, Marina; Berna, Giovanni; Cavoretto, Dario; Celeste, Fabrizio; Muratori, Manuela; Guazzi, Maurizio D

    2004-01-01

    Tele-echocardiography is not widely used because of lengthy transmission times when using standard Motion Pictures Expert Groups (MPEG)-2 lossy compression algorythms, unless expensive high bandwidth lines are used. We sought to validate the newer MPEG-4 algorythms to allow further reduction in echocardiographic motion video file size. Four cardiologists expert in echocardiography read blindly 165 randomized uncompressed and compressed 2D and color Doppler normal and pathologic motion images. One Digital Video and 3 MPEG-4 compression algorythms were tested, the latter at 3 decreasing compression quality levels (100%, 65% and 40%). Mean diagnostic and image quality scores were computed for each file and compared across the 3 compression levels using uncompressed files as controls. File dimensions decreased from a range of uncompressed 12-83 MB to MPEG-4 0.03-2.3 MB. All algorythms showed mean scores that were not significantly different from uncompressed source, except the MPEG-4 DivX algorythm at the highest selected compression (40%, p=.002). These data support the use of MPEG-4 compression to reduce echocardiographic motion image size for transmission purposes, allowing cost reduction through use of low bandwidth lines.

  8. Comparison of the serum sensitivity of uropathogenic strains of Escherichia coli isolated from different diagnostic groups

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    J. Vraneš,

    2005-02-01

    Full Text Available The bactericidal activity of serum caused by complement system is an important defence mechanism protecting the host organism against infection. The capacity to resist bactericidal activity of normal human serum contributes to the virulence of many gram-negative pathogens. Serum resistance in bacteria has been attributed to their surface components, but exact mechanism of resistance which most likely involves multiple factors is not well understood. In this study, the capacity of Escherichia coli to resist the bactericidal action of serum was examined in 85 clinical isolates obtained from patients with acute pyelonephritis (n=23, acute cystitis (n=22, chronic pyelonephritis (n=22 and asymptomatic bacteriuria (n=18. Serum sensitivity was also examined in relation to the serogroup specificity and expression of the different adhesins of the strains.Bacterial susceptibility to serum killing was measured by assessing regrowth after incubation in serum according to Schiller and Hatch method. The adhesins of E. coli were determined by hemagglutination and inhibition of hemagglutiation, and serotyping was performed on glass slides and confirmed using a mechanized microtechnique.The significant correlation between serum resistance of uropathogenic strains of E. coli and expression of P-fimbriae and O6 serogroup was observed.Theincidence of serum-resistant E. coli strains was significantly higher in strains isolated from urine of patients with acute pyelonephritis, as compared to strains isolated in other diagnostic groups, which is in accordance with higher virulence and invasive potential of these strains.

  9. Potential pathogenic role of aggregative-adhering Corynebacterium diphtheriae of different clonal groups in endocarditis.

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    Hirata Jr, R; Pereira, G A; Filardy, A A; Gomes, D L R; Damasco, P V; Rosa, A C P; Nagao, P E; Pimenta, F P; Mattos-Guaraldi, A L

    2008-11-01

    Invasive diseases caused by Corynebacterium diphtheriae have been described increasingly. Several reports indicate the destructive feature of endocarditis attributable to nontoxigenic strains. However, few reports have dealt with the pathogenicity of invasive strains. The present investigation demonstrates a phenotypic trait that may be used to identify potentially invasive strains. The study also draws attention to clinical and microbiological aspects observed in 5 cases of endocarditis due to C. diphtheriae that occurred outside Europe. Four cases occurred in female school-age children (7-14 years) treated at different hospitals in Rio de Janeiro, Brazil. All patients developed other complications including septicemia, renal failure and/or arthritis. Surgical treatment was performed on 2 patients for valve replacement. Lethality was observed in 40% of the cases. Microorganisms isolated from 5 blood samples and identified as C. diphtheriae subsp mitis (N = 4) and C. diphtheriae subsp gravis (N = 1) displayed an aggregative adherence pattern to HEp-2 cells and identical one-dimensional SDS-PAGE protein profiles. Aggregative-adhering invasive strains of C. diphtheriae showed 5 distinct RAPD profiles. Despite the clonal diversity, all 5 C. diphtheriae invasive isolates seemed to display special bacterial adhesive properties that may favor blood-barrier disruption and systemic dissemination of bacteria. In conclusion, blood isolates from patients with endocarditis exhibited a unique adhering pattern, suggesting a pathogenic role of aggregative-adhering C. diphtheriae of different clones in endocarditis. Accordingly, the aggregative-adherence pattern may be used as an indication of some invasive potential of C. diphtheriae strains.

  10. Potential pathogenic role of aggregative- adhering Corynebacterium diphtheriae of different clonal groups in endocarditis

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    R. Hirata Jr.

    2008-11-01

    Full Text Available Invasive diseases caused by Corynebacterium diphtheriae have been described increasingly. Several reports indicate the destructive feature of endocarditis attributable to nontoxigenic strains. However, few reports have dealt with the pathogenicity of invasive strains. The present investigation demonstrates a phenotypic trait that may be used to identify potentially invasive strains. The study also draws attention to clinical and microbiological aspects observed in 5 cases of endocarditis due to C. diphtheriae that occurred outside Europe. Four cases occurred in female school-age children (7-14 years treated at different hospitals in Rio de Janeiro, Brazil. All patients developed other complications including septicemia, renal failure and/or arthritis. Surgical treatment was performed on 2 patients for valve replacement. Lethality was observed in 40% of the cases. Microorganisms isolated from 5 blood samples and identified as C. diphtheriae subsp mitis (N = 4 and C. diphtheriae subsp gravis (N = 1 displayed an aggregative adherence pattern to HEp-2 cells and identical one-dimensional SDS-PAGE protein profiles. Aggregative-adhering invasive strains of C. diphtheriae showed 5 distinct RAPD profiles. Despite the clonal diversity, all 5 C. diphtheriae invasive isolates seemed to display special bacterial adhesive properties that may favor blood-barrier disruption and systemic dissemination of bacteria. In conclusion, blood isolates from patients with endocarditis exhibited a unique adhering pattern, suggesting a pathogenic role of aggregative-adhering C. diphtheriae of different clones in endocarditis. Accordingly, the aggregative-adherence pattern may be used as an indication of some invasive potential of C. diphtheriae strains.

  11. Prevalence of cytomegalovirus infection in different patient groups of a urban university in Brazil

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    José Hermôgenes Rocco Suassuna

    1995-06-01

    Full Text Available This study sought for etndence of previous CMV infection in patients of a general hospital serving the low income population of Rio de Janeiro. An enzyme immunoassay was used to detect anti-CMV antibodies in 713 typical hospital patients classified into eight different groups. Positive tests were found in 87% of pregnant women, 85% of newborns, 61% of pediatric patients, 77% of adolescent patients, 81% of adult patients, 87% of dialysed transplant candidates, 89% of kidney donors, and 92% of patients after transplantation. Depending of the subgroup studied these results carry different meanings and necessitate different clinical approaches. The risk of congenital disease is probably low in view of the reduced number of pregnant women still susceptible to primary infection. The number of primary infections will also be low in transplant recipients. However, those still susceptible will almost certainly acquire the infection from, their donor. Prophylactic CMV matching in kidney transplantation is not a realistic approach due to the low probability of finding pairs of seronegative donors and recipients.Evidência de infecção passada por citomegalovírus foi pesquisada em pacientes de um hospital que serve à população de baixa renda na cidade do Rio de faneiro. Realizou-se, com um imunoensaio enzimãtico, a pesquisa de anticoipos anti-CMV em 713 pacientes hospitalares, divididos em oito grupos. As taxas observadas foram 87% para grávidas, 85% para recém-natos, 61% para pacientes pediátricos, 77% para adolescentes e 81% para adultos, 87% para pacientes em diálise, 89% para doadores de rim e 92% para pacientes após o transplante renal. Estes resultados têm diferentes significados e implicam em diferentes abordagens clínicas dependendo do subgrupo estudado. O risco de infecção congênita provavelmente é baixo devido ao reduzido número de mulheres grávidas ainda susceptíveis a infecções primárias. Pelo mesmo motivo, o número de

  12. Microsporogenesis in Paspalum conspersum Schrad. (Virgata group) with different ploidy levels.

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    Janke, L; Souza, F H D; Valls, J F M; Pagliarini, M S

    2013-10-24

    Knowledge about the cytology and reproductive behavior of a species is indispensable for hybridization programs. This is especially true for species belonging to the genus Paspalum, among which apomixis and a wide range of ploidy levels are frequently found. Paspalum conspersum Schrad. is a robust and warm-season perennial bunchgrass native to South America. Previous studies have indicated that both tetraploid and hexaploid races exist in this species; however, only information related to tetraploids has been applied to another taxon. In this study, a cytological investigation in two Brazilian accessions collected in different regions revealed tetraploidy in the accession BRA-012823 (2n = 4x = 40), with chromosome pairing in bivalents and normal meiosis and tetrad formation, and pentaploidy (2n = 5x = 50) in the accession BRA-022748, which presented total asynapsis. In this latter accession, 50 univalents could be scored at diakinesis. After alignment at the metaphase plate, sister chromatids segregated to the poles. Only one meiotic division (equational) occurred, and after cytokinesis, 100% of the dyads that formed had 2n microspores. The meiotic behavior during microsporogenesis, which showed 10 delayed univalents to reach the metaphase plate, suggests that this accession is a recent natural hybrid constituted by a parental genome with 40 chromosomes and another with 10 chromosomes. The potential usage of these accessions in Paspalum breeding has been discussed.

  13. The Influence of Culture on Agroecosystem Structure: A Comparison of the Spatial Patterns of Homegardens of Different Ethnic Groups in Thailand and Vietnam.

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    Pijika Timsuksai

    Full Text Available Different ethnic groups have evolved distinctive cultural models which guide their interactions with the environment, including their agroecosystems. Although it is probable that variations in the structures of homegardens among separate ethnic groups reflect differences in the cultural models of the farmers, empirical support for this assumption is limited. In this paper the modal horizontal structural patterns of the homegardens of 8 ethnic groups in Northeast Thailand and Vietnam are described. Six of these groups (5 speaking Tai languages and 1 speaking Vietnamese live in close proximity to each other in separate villages in Northeast Thailand, and 2 of the groups (one Tai-speaking and one Vietnamese-speaking live in different parts of Vietnam. Detailed information on the horizontal structure of homegardens was collected from samples of households belonging to each group. Although each ethnic group has a somewhat distinctive modal structure, the groups cluster into 2 different types. The Tai speaking Cao Lan, Kalaeng, Lao, Nyaw, and Yoy make up Type I while both of the Vietnamese groups, along with the Tai speaking Phu Thai, belong to Type II. Type I gardens have predominantly organic shapes, indeterminate boundaries, polycentric planting patterns, and multi-species composition within planting areas. Type II homegardens have geometric shapes, sharp boundaries, lineal planting patterns, and mono-species composition of planting areas. That the homegardens of most of the Tai ethnic groups share a relatively similar horizontal structural pattern that is quite different from the pattern shared by both of the Vietnamese groups suggests that the spatial layout of homegardens is strongly influenced by their different cultural models.

  14. The Influence of Culture on Agroecosystem Structure: A Comparison of the Spatial Patterns of Homegardens of Different Ethnic Groups in Thailand and Vietnam.

    Science.gov (United States)

    Timsuksai, Pijika; Rambo, A Terry

    2016-01-01

    Different ethnic groups have evolved distinctive cultural models which guide their interactions with the environment, including their agroecosystems. Although it is probable that variations in the structures of homegardens among separate ethnic groups reflect differences in the cultural models of the farmers, empirical support for this assumption is limited. In this paper the modal horizontal structural patterns of the homegardens of 8 ethnic groups in Northeast Thailand and Vietnam are described. Six of these groups (5 speaking Tai languages and 1 speaking Vietnamese) live in close proximity to each other in separate villages in Northeast Thailand, and 2 of the groups (one Tai-speaking and one Vietnamese-speaking) live in different parts of Vietnam. Detailed information on the horizontal structure of homegardens was collected from samples of households belonging to each group. Although each ethnic group has a somewhat distinctive modal structure, the groups cluster into 2 different types. The Tai speaking Cao Lan, Kalaeng, Lao, Nyaw, and Yoy make up Type I while both of the Vietnamese groups, along with the Tai speaking Phu Thai, belong to Type II. Type I gardens have predominantly organic shapes, indeterminate boundaries, polycentric planting patterns, and multi-species composition within planting areas. Type II homegardens have geometric shapes, sharp boundaries, lineal planting patterns, and mono-species composition of planting areas. That the homegardens of most of the Tai ethnic groups share a relatively similar horizontal structural pattern that is quite different from the pattern shared by both of the Vietnamese groups suggests that the spatial layout of homegardens is strongly influenced by their different cultural models.

  15. The differences between Groupon and other group-buying intermediaries: : from transactional and relational coordination perspectives

    OpenAIRE

    Jia, Yijing; Wu, Qiongshen

    2011-01-01

    Groupon is a popular group-buying website offering daily deals and has experiencedfast growth. It has attracted amounts of imitators and they sprang up all over the world.We treat this phenomenon by taking Groupon as an intermediary executing coordinationbetween merchants and customers in the group-buying activities. To see the particularpractices of Groupon in operating transactional and relational coordination mechanisms,we collect diverse group-buying forms from the earliest buying club si...

  16. Do structured arrangements for multidisciplinary peer group supervision make a difference for allied health professional outcomes?

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    Kuipers P

    2013-10-01

    Full Text Available Pim Kuipers,1,2 Susan Pager,1 Karen Bell,3 Fiona Hall,4 Melissa Kendall2,5,6 1Centre for Functioning and Health Research, Metro South Health, Brisbane, Queensland, Australia; 2Centre for Community Science, School of Human Services, Griffith University, Queensland, Australia; 3Darling Downs Hospital and Health Service, Queensland, Australia; 4Allied Health Professions Office of Queensland, Health Service and Innovation Division, Queensland, Australia; 5Acquired Brain Injury Outreach Service, Metro South Health, Brisbane, Queensland, Australia; 6Transitional Rehabilitation Programme, Metro South Health, Brisbane, Queensland, Australia Abstract: Peer group supervision, particularly in multidisciplinary formats, presents a potential means of providing professional support, and specifically clinical supervision, for allied health professionals. Debate exists regarding the extent to which the activities of these groups should be formalized. Results drawn from an evaluation of a large-scale peer group supervision initiative are described. Analysis of 192 responses from professionals involved in peer groups indicates that participants in groups that used formal documentation – which adopted the tools provided in training, and particularly those that used formal evaluation of their groups – rated their groups as having better processes and greater impact. Interestingly, multidisciplinary peer groups were rated as having similar impacts, processes, and purposes as the more homogenous single-discipline groups. It is concluded that the implementation of formal arrangements enhances the processes and outcomes of peer groups implemented for professional support and clinical supervision. Multidisciplinary membership of such groups is perceived as equally beneficial as single-discipline groups. Keywords: allied health, professional supervision, clinical supervision, professional support, multidisciplinary

  17. Selective interactions between vertebrate polycomb homologs and the SUV39H1 histone lysine methyltransferase suggest that histone H3-K9 methylation contributes to chromosomal targeting of Polycomb group proteins.

    Science.gov (United States)

    Sewalt, Richard G A B; Lachner, Monika; Vargas, Mark; Hamer, Karien M; den Blaauwen, Jan L; Hendrix, Thijs; Melcher, Martin; Schweizer, Dieter; Jenuwein, Thomas; Otte, Arie P

    2002-08-01

    Polycomb group (PcG) proteins form multimeric chromatin-associated protein complexes that are involved in heritable repression of gene activity. Two distinct human PcG complexes have been characterized. The EED/EZH2 PcG complex utilizes histone deacetylation to repress gene activity. The HPC/HPH PcG complex contains the HPH, RING1, BMI1, and HPC proteins. Here we show that vertebrate Polycomb homologs HPC2 and XPc2, but not M33/MPc1, interact with the histone lysine methyltransferase (HMTase) SUV39H1 both in vitro and in vivo. We further find that overexpression of SUV39H1 induces selective nuclear relocalization of HPC/HPH PcG proteins but not of the EED/EZH2 PcG proteins. This SUV39H1-dependent relocalization concentrates the HPC/HPH PcG proteins to the large pericentromeric heterochromatin domains (1q12) on human chromosome 1. Within these PcG domains we observe increased H3-K9 methylation. Finally, we show that H3-K9 HMTase activity is associated with endogenous HPC2. Our findings suggest a role for the SUV39H1 HMTase and histone H3-K9 methylation in the targeting of human HPC/HPH PcG proteins to modified chromatin structures.

  18. Chemical composition and in vitro digestibility of indigenous pasture plants in different plant groups (Preliminary report

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    Torstein H. Garmo

    1986-06-01

    Full Text Available Several plant species from the following plant groups: ferns + horsetails, lichens, conifers (juniper, three leaves (Salix spp., Betula spp., Populus tremula, Sorbus aucuparid, heathers, grassens, rushes/sedges and forbs were collected in a mountain area of southerns Norway during the growing season from the 15th of June up to the 15th of September the years 1982 — 1984. Mean values (% of dry matter of the different chemical constituents and in vitro dry matter digestibility of the different plant groups sampled throughout the growing season are given in Table 2. The mean crude protein content varied from 4.1% in lichens up to 17.5% in forbs; the crude fat were lowest for rushes/sedges (1.9% and highest in juniper (13.3%; the crude fibre varied from 14.1% to 26.1% of three leaves and grasses, respectively; NFE showed lowest values for grasses (54% and highest in lichens (74%. Ferns + horsetails contained the greatest (13.3% and lichens the lowest (1.9% amount of ash of the different plant groups. The levels of the macrominerals calcium, phosphorus, magnesium and potassium were all lowest in lichens (0.15; 0.09; 0.05; 0.13% and highest in the forbs (1.19; 0.36; 0.37; 1.65%. Sodium levels varied from 0.029% in the heathers to 0.116% of ferns + horsetails. The forbs showed the highest mean in vitro dry matter digestibility (69% and lichens the lowest (35%. However, the in vitro method (using sheep rumen inoculum probably underestimates the dry matter digestibility of lichens, three leaves, juniper and heathers. Great variations in most of the chemical constituents as well as in vitro dry matter digestibility throughout the growing season for the different plant groups were demonstrated (Table 2. Keywords: nutrients, macrominerals, digestibility, livestock, wild ruminants, native pastures.Kjemisk innhald og in vitro fordøyelsesgrad av planter innan ulike plantegrupper frå fjellbeite (Førebels rapport.Abstract in Norwwegia