WorldWideScience

Sample records for group core series

  1. Diversity of Authors & Illustrators in First Grade Core Reading Series

    Science.gov (United States)

    Buescher, Eileen M.; Lightner, Sarah C.; Kelly, Robert H.

    2016-01-01

    The purposes of this study were to examine the diversity of the authors and illustrators in core reading series and to evaluate the opportunities and limitations of these texts in relation to the goals of multicultural education. The authors began their research concerned about whose stories are told in core reading series, and who gets to tell…

  2. Constructing Weyl group multiple Dirichlet series

    Science.gov (United States)

    Chinta, Gautam; Gunnells, Paul E.

    2010-01-01

    Let Phi be a reduced root system of rank r . A Weyl group multiple Dirichlet series for Phi is a Dirichlet series in r complex variables s_1,dots,s_r , initially converging for {Re}(s_i) sufficiently large, that has meromorphic continuation to {{C}}^r and satisfies functional equations under the transformations of {{C}}^r corresponding to the Weyl group of Phi . A heuristic definition of such a series was given by Brubaker, Bump, Chinta, Friedberg, and Hoffstein, and they have been investigated in certain special cases by others. In this paper we generalize results by Chinta and Gunnells to construct Weyl group multiple Dirichlet series by a uniform method and show in all cases that they have the expected properties.

  3. Cosmetology Core. Teacher Workbook. Cosmetology Series.

    Science.gov (United States)

    Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

    This teacher workbook, which is part of a series of publications designed to support instruction in Oklahoma vocational cosmetology programs, consists of 13 units of information and skills that are basic to all major instructional divisions of a cosmetology course of study. The unit topics are as follows: identifying cosmetology careers/displaying…

  4. Hunton Group core workshop and field trip

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, K.S. [ed.

    1993-12-31

    The Late Ordovician-Silurian-Devonian Hunton Group is a moderately thick sequence of shallow-marine carbonates deposited on the south edge of the North American craton. This rock unit is a major target for petroleum exploration and reservoir development in the southern Midcontinent. The workshop described here was held to display cores, outcrop samples, and other reservoir-characterization studies of the Hunton Group and equivalent strata throughout the region. A field trip was organized to complement the workshop by allowing examination of excellent outcrops of the Hunton Group of the Arbuckle Mountains.

  5. On Central Series of the Multiplicative Group of Division Rings

    Institute of Scientific and Technical Information of China (English)

    Roozbeh Hazrat

    2002-01-01

    This paper studies the descending central series of the multiplicative group of a division ring. We show that certain properties, which a term in the descending central series may have, can be lifted to the full multiplicative group,and determine quotients of consecutive terms in the descending central series in tame Henselian unramified or totally ramified cases.

  6. Vegetables and other core food groups

    NARCIS (Netherlands)

    Poelman, Astrid A.M.; Delahunty, Conor M.; Graaf, de Kees

    2017-01-01

    Vegetables are the food category least liked by children. This research investigated the sensory properties of vegetables vis-a-vis other core foods that comprise children's diets, to determine to what degree low acceptance of vegetables can be attributed to sensory properties. Vegetables (n = 34

  7. Lacunary Fourier Series for Compact Quantum Groups

    Science.gov (United States)

    Wang, Simeng

    2016-05-01

    This paper is devoted to the study of Sidon sets, {Λ(p)} -sets and some related notions for compact quantum groups. We establish several different characterizations of Sidon sets, and in particular prove that any Sidon set in a discrete group is a strong Sidon set in the sense of Picardello. We give several relations between Sidon sets, {Λ(p)} -sets and lacunarities for L p -Fourier multipliers, generalizing a previous work by Blendek and Michalic̆ek. We also prove the existence of {Λ(p)} -sets for orthogonal systems in noncommutative L p -spaces, and deduce the corresponding properties for compact quantum groups. Central Sidon sets are also discussed, and it turns out that the compact quantum groups with the same fusion rules and the same dimension functions have identical central Sidon sets. Several examples are also included.

  8. Abundance profiles and cool cores in galaxy groups

    CERN Document Server

    Johnson, Ria; Ponman, Trevor J; Rasmussen, Jesper; Sanderson, Alastair J R

    2011-01-01

    Using data from the Two Dimensional XMM-Newton Group Survey (2dXGS), we have examined the abundance profile properties of both cool core (CC) and non cool core (NCC) galaxy groups. The ten NCC systems in our sample represent a population which to date has been poorly studied in the group regime. Fitting the abundance profiles as a linear function of log radius, we find steep abundance gradients in cool core (CC) systems, with a slope of -0.54+/-0.07. In contrast, non cool core (NCC) groups have profiles consistent with uniform metallicity. Many CC groups show a central abundance dip or plateau, and we find evidence for anticorrelation between the core abundance gradient and the 1.4 GHz radio power of the brightest group galaxy (BGG) in CC systems. This may indicate the effect of AGN-driven mixing within the central ~0.1r_500. It is not possible to discern whether such behaviour is present in the NCC groups, due to the small and diverse sample with the requisite radio data. The lack of strong abundance gradien...

  9. Weyl group multiple Dirichlet series of type C

    CERN Document Server

    Beineke, Jennifer; Frechette, Sharon

    2010-01-01

    We develop the theory of Weyl group multiple Dirichlet series for root systems of type C. For an arbitrary root system of rank r and a positive integer n, these are Dirichlet series in r complex variables with analytic continuation and functional equations isomorphic to the associated Weyl group. In type C, they conjecturally arise from the Fourier-Whittaker coefficients of minimal parabolic Eisenstein series on an n-fold metaplectic cover of SO(2r+1). For any odd n, we construct an infinite family of Dirichlet series conjecturally satisfying the above analytic properties. The coefficients of these series are exponential sums built from Gelfand-Tsetlin bases of certain highest weight representations. Previous attempts to define such series by Brubaker, Bump, and Friedberg in [6] and [7] required n to be sufficiently large, so that coefficients could be described by Weyl group orbits. We demonstrate that our construction agrees with that of [6] and [7] in the case where both series are defined, and hence inher...

  10. Principal series representations of metaplectic groups over local fields

    CERN Document Server

    McNamara, Peter J

    2009-01-01

    Let G be a split reductive algebraic group over a non-archimedean local field. We study the representation theory of a central extension $\\G$ of G by a cyclic group of order n, under some mild tameness assumptions on n. In particular, we focus our attention on the development of the theory of principal series representations for $\\G$ and applications of this theory.

  11. Performance of Artificial Intelligence Workloads on the Intel Core 2 Duo Series Desktop Processors

    Directory of Open Access Journals (Sweden)

    Abdul Kareem PARCHUR

    2010-12-01

    Full Text Available As the processor architecture becomes more advanced, Intel introduced its Intel Core 2 Duo series processors. Performance impact on Intel Core 2 Duo processors are analyzed using SPEC CPU INT 2006 performance numbers. This paper studied the behavior of Artificial Intelligence (AI benchmarks on Intel Core 2 Duo series processors. Moreover, we estimated the task completion time (TCT @1 GHz, @2 GHz and @3 GHz Intel Core 2 Duo series processors frequency. Our results show the performance scalability in Intel Core 2 Duo series processors. Even though AI benchmarks have similar execution time, they have dissimilar characteristics which are identified using principal component analysis and dendogram. As the processor frequency increased from 1.8 GHz to 3.167 GHz the execution time is decreased by ~370 sec for AI workloads. In the case of Physics/Quantum Computing programs it was ~940 sec.

  12. [Crestal core elevation technique--case series and literature review].

    Science.gov (United States)

    Kolerman, R; Barnea, E

    2008-04-01

    Sinus floor augmentation is the most common surgical procedure for gaining bone volume in the posterior maxilla. The purpose of this procedure is to enable implant placement un edentulous ridges. The most common techniques for sinus augmentation are: 1. Bone added osteotome sinus floor elevation (BAOSFE). 2. Crestal core elevation (CCE). 3. Lateral window technique (LWT). Since the early 80's many articles describing the successful use of different augmentation materials for sinus elevation have been published. Although many articles have been published on the lateral window technique and the osteotome technique as described by Summers, few articles have been published on the crestsal core sinus elevation technique. This technique, first described by Summers, includes the use of wide diameter osteotomes and trephine bur with a diameter of 6 m"m. This technique is implemented in situations when the available bone for implant placement is less than 6 m"m , which impairs the possibility of achieving primary stability of the implant. In those cases crestal core elevation is performed and implant placement is postponed 3-8 months later. Modification of the technique described by Summers was published by Fugazzoto, this technique is implemented concomitant with the extraction of the upper molars. The crestal core elevation technique (CCE), which is based on the BAOSFE (Bone Added Osteotome Sinus Floor Elevation), is based on the principle of hydraulic force acting on fluids and particles which transfer the vector of force to all direction, in this case the sinus membrane. The detached core of interradicular bone prior to osteotome placement and malleting significantly reduces surgical trauma to the patient especially in cases where a significant portion of the pre-disease interradicular bone remains. The concomitant placement of particulate material and a membrane at the time of tooth extraction offers the advantage of minimizing if not eliminating significant 3

  13. Poincare series of subsets of affine Weyl groups

    OpenAIRE

    Viswanath, Sankaran

    2006-01-01

    In this note, we identify a natural class of subsets of affine Weyl groups whose Poincare series are rational functions. This class includes the sets of minimal coset representatives of reflection subgroups. As an application, we construct a generalization of the classical length-descent generating function, and prove its rationality.

  14. The amenability of the substitution group of formal power series

    Energy Technology Data Exchange (ETDEWEB)

    Babenko, Ivan K; Bogatyi, Semen A

    2011-04-30

    We study the amenability property for the group J(k) of formal power series in one variable with coefficients in a commutative ring k with identity. We show that there exists an invariant mean on the space C{sub u}*(J(k)) of uniformly continuous bounded functions on this group. This is equivalent to the fact that every continuous action of J(k) on every compact space has an invariant probability measure.

  15. Systematic mining of analog series with related core structures in multi-target activity space.

    Science.gov (United States)

    Gupta-Ostermann, Disha; Hu, Ye; Bajorath, Jürgen

    2013-08-01

    We have aimed to systematically extract analog series with related core structures from multi-target activity space to explore target promiscuity of closely related analogous. Therefore, a previously introduced SAR matrix structure was adapted and further extended for large-scale data mining. These matrices organize analog series with related yet distinct core structures in a consistent manner. High-confidence compound activity data yielded more than 2,300 non-redundant matrices capturing 5,821 analog series that included 4,288 series with multi-target and 735 series with multi-family activities. Many matrices captured more than three analog series with activity against more than five targets. The matrices revealed a variety of promiscuity patterns. Compound series matrices also contain virtual compounds, which provide suggestions for compound design focusing on desired activity profiles.

  16. An algorithm for multi-group two-dimensional neutron diffusion kinetics in nuclear reactor cores

    OpenAIRE

    Marcelo Schramm

    2016-01-01

    The objective of this thesis is to introduce a new methodology for two{dimensional multi{ group neutron diffusion kinetics in a reactor core. The presented methodology uses a polyno- mial approximation in a rectangular homogeneous domain with non{homogeneous boundary conditions. As it consists on a truncated Taylor series, its error estimates varies with the size of the rectangle. The coefficients are obtained mainly by their relations with the independent term, which is determined by the dif...

  17. MTR core loading pattern optimization using burnup dependent group constants

    Directory of Open Access Journals (Sweden)

    Iqbal Masood

    2008-01-01

    Full Text Available A diffusion theory based MTR fuel management methodology has been developed for finding superior core loading patterns at any stage for MTR systems, keeping track of burnup of individual fuel assemblies throughout their history. It is based on using burnup dependent group constants obtained by the WIMS-D/4 computer code for standard fuel elements and control fuel elements. This methodology has been implemented in a computer program named BFMTR, which carries out detailed five group diffusion theory calculations using the CITATION code as a subroutine. The core-wide spatial flux and power profiles thus obtained are used for calculating the peak-to-average power and flux-ratios along with the available excess reactivity of the system. The fuel manager can use the BFMTR code for loading pattern optimization for maximizing the excess reactivity, keeping the peak-to-average power as well as flux-ratio within constraints. The results obtained by the BFMTR code have been found to be in good agreement with the corresponding experimental values for the equilibrium core of the Pakistan Research Reactor-1.

  18. Organized thiol functional groups in mesoporous core shell colloids

    Energy Technology Data Exchange (ETDEWEB)

    Marchena, Martin H. [Gerencia Quimica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica (CNEA), Avda. Gral. Paz 1499, B1650KNA Buenos Aires (Argentina); Granada, Mara [Centro Atomico Bariloche-CNEA, 8400 San Carlos de Bariloche (Argentina); Instituto Balseiro-Centro Atomico Bariloche-CNEA, San Carlos de Bariloche 8400 (Argentina); Bordoni, Andrea V. [Gerencia Quimica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica (CNEA), Avda. Gral. Paz 1499, B1650KNA Buenos Aires (Argentina); Joselevich, Maria [Asociacion Civil Expedicion Ciencia, Cabrera 4948, C1414BGP Buenos Aires (Argentina); Troiani, Horacio [Centro Atomico Bariloche-CNEA, 8400 San Carlos de Bariloche (Argentina); Instituto Balseiro-Centro Atomico Bariloche-CNEA, San Carlos de Bariloche 8400 (Argentina); Williams, Federico J. [DQIAQyF-INQUIMAE FCEN, Universidad de Buenos Aires, Ciudad Universitaria, Pabellon II, C1428EHA Buenos Aires (Argentina); Wolosiuk, Alejandro, E-mail: wolosiuk@cnea.gov.ar [Gerencia Quimica, Centro Atomico Constituyentes, Comision Nacional de Energia Atomica (CNEA), Avda. Gral. Paz 1499, B1650KNA Buenos Aires (Argentina)

    2012-03-15

    The co-condensation in situ of tetraethoxysilane (TEOS) and mercaptopropyltrimethoxysilane (MPTMS) using cetyltrimethylammonium bromide (CTAB) as a template results in the synthesis of multilayered mesoporous structured SiO{sub 2} colloids with 'onion-like' chemical environments. Thiol groups were anchored to an inner selected SiO{sub 2} porous layer in a bilayered core shell particle producing different chemical regions inside the colloidal layered structure. X-Ray Photoelectron Spectroscopy (XPS) shows a preferential anchoring of the -SH groups in the double layer shell system, while porosimetry and simple chemical modifications confirm that pores are accessible. We can envision the synthesis of interesting colloidal objects with defined chemical environments with highly controlled properties. - Graphical abstract: Mesoporous core shell SiO{sub 2} colloids with organized thiol groups. Highlights: Black-Right-Pointing-Pointer Double shell mesoporous silica colloids templated with CTAB. Black-Right-Pointing-Pointer Sequential deposition of mesoporous SiO{sub 2} layers with different chemistries. Black-Right-Pointing-Pointer XPS shows the selective functionalization of mesoporous layers with thiol groups.

  19. Joint analysis of celestial pole offset and free core nutation series

    Science.gov (United States)

    Malkin, Zinovy

    2017-07-01

    Three combined celestial pole offset (CPO) series computed at the Paris Observatory (C04), the United States Naval Observatory (USNO), and the International VLBI Service for Geodesy and Astrometry (IVS), as well as six free core nutation (FCN) models, were compared from different perspectives, such as stochastic and systematic differences, and FCN amplitude and phase variations. The differences between the C04 and IVS CPO series were mostly stochastic, whereas a low-frequency bias at the level of several tens of μas was found between the C04 and USNO CPO series. The stochastic differences between the C04 and USNO series became considerably smaller when computed at the IVS epochs, which can indicate possible problems with the interpolation of the IVS data at the midnight epochs during the computation of the C04 and USNO series. The comparison of the FCN series showed that the series computed with similar window widths of 1.1-1.2 years were close to one another at a level of 10-20 μas, whereas the differences between these series and the series computed with a larger window width of 4 and 7 years reached 100 μas. The dependence of the FCN model on the underlying CPO series was investigated. The RMS differences between the FCN models derived from the C04, USNO, and IVS CPO series were at a level of approximately 15 μas, which was considerably smaller than the differences among the CPO series. The analysis of the differences between the IVS, C04, and USNO CPO series suggested that the IVS series would be preferable for both precession-nutation and FCN-related studies.

  20. Joint analysis of celestial pole offset and free core nutation series

    Science.gov (United States)

    Malkin, Zinovy

    2016-10-01

    Three combined celestial pole offset (CPO) series computed at the Paris Observatory (C04), the United States Naval Observatory (USNO), and the International VLBI Service for Geodesy and Astrometry (IVS), as well as six free core nutation (FCN) models, were compared from different perspectives, such as stochastic and systematic differences, and FCN amplitude and phase variations. The differences between the C04 and IVS CPO series were mostly stochastic, whereas a low-frequency bias at the level of several tens of μ as was found between the C04 and USNO CPO series. The stochastic differences between the C04 and USNO series became considerably smaller when computed at the IVS epochs, which can indicate possible problems with the interpolation of the IVS data at the midnight epochs during the computation of the C04 and USNO series. The comparison of the FCN series showed that the series computed with similar window widths of 1.1-1.2 years were close to one another at a level of 10-20 μ as, whereas the differences between these series and the series computed with a larger window width of 4 and 7 years reached 100 μ as. The dependence of the FCN model on the underlying CPO series was investigated. The RMS differences between the FCN models derived from the C04, USNO, and IVS CPO series were at a level of approximately 15 μ as, which was considerably smaller than the differences among the CPO series. The analysis of the differences between the IVS, C04, and USNO CPO series suggested that the IVS series would be preferable for both precession-nutation and FCN-related studies.

  1. Plagioclase in the Skaergaard intrusion. Part 1: Core and rim compositions in the layered series

    Science.gov (United States)

    Toplis, Michael J.; Brown, William L.; Pupier, Elsa

    2008-03-01

    The anorthite content of plagioclase grains (XAn) in 12 rocks from the layered series of the Skaergaard intrusion has been studied by electron microprobe (typically ˜30 core and ˜70 rim analyses per thin section). Mean core compositions vary continuously from An66 at the base of the layered series (LZa) to An32-30 at the top. On the other hand, crystal rims are of approximately constant composition (An50 ± 1) from the LZa to the lower Middle Zone (MZ). Above the MZ, core and rim compositions generally overlap. Profiles across individual plagioclase grains from the lower zone show that most crystals have an external zone buffered at XAn ˜50 ± 1. The simplest explanation for these features is that during postcumulus crystallization in the lower zone, interstitial liquids passed through a density maximum. This interpretation is consistent with proposed liquid lines of descent that predict silica enrichment of the liquid associated with the appearance of cumulus magnetite.

  2. Groups of Groups: The Role of Group Learning in Building Social Capital. CRLRA Discussion Paper Series.

    Science.gov (United States)

    Kilpatrick, Sue; Bell, Rowena; Falk, Ian

    The Centre for Research and Learning in Regional Australia is investigating the elements of social capital and developing a set of indicators that show when social capital is building. The indicators can be used where groups or organizations with a shared purpose engage in productive interactions that benefit not only the individual member groups…

  3. The Chandra Deep Group Survey -- cool core evolution in groups and clusters of galaxies

    CERN Document Server

    Pascut, Aurelia

    2014-01-01

    We report the results of a study which assembles deep observations with the ACIS-I instrument on the Chandra Observatory to study the evolution in the core properties of a sample of galaxy groups and clusters out to redshifts $z\\approx 1.3$. A search for extended objects within these fields yields a total of 62 systems for which redshifts are available, and we added a further 24 non-X-ray-selected clusters, to investigate the impact of selection effects and improve our statistics at high redshift. Six different estimators of cool core strength are applied to these data: the entropy (K) and cooling time ($t_{cool}$) within the cluster core, the cooling time as a fraction of the age of the Universe ($t_{cool}/t_{Uni}$), and three estimators based on the cuspiness of the X-ray surface brightness profile. A variety of statistical tests are used to quantify evolutionary trends in these cool core indicators. In agreement with some previous studies, we find that there is significant evolution in $t_{cool}/t_{Uni}$, ...

  4. Quality and overlap of individual core areas are related to group tenure in female spider monkeys.

    Science.gov (United States)

    Asensio, Norberto; Schaffner, Colleen M; Aureli, Filippo

    2015-07-01

    In species with a high degree of fission-fusion dynamics group members may differ in the use of the group home range to reduce food competition. Such differential use may result in distinct individual core areas. We studied core area quality and overlap among 21 female spider monkeys belonging to the same group over a period of 4 years. Core areas ranged between 62 and 161 ha with a mean overlap of 56% between any given two females. Only a small portion (mean = 3 ha) of each individual core area was used exclusively. No single part of the home range was used as core area by all females, and only an area of less than 1 ha was used as part of the core area by 20 of the 21 females. The time a female spent in the group (i.e., group tenure) was associated with characteristics of the core areas: the longer the group tenure, the better the quality of her core area. In addition, the longer the time two females spent together in the same group, the larger the overlap between their individual core areas. As this result was obtained while controlling for the time two females spent together in the same subgroup, females may reduce direct competition by using the same resource at different times. In sum, spider monkey females' group tenure plays a central role in the quality and overlapping patterns of their individual core areas.

  5. Core muscle activity in a series of balance exercises with different stability conditions.

    Science.gov (United States)

    Calatayud, Joaquin; Borreani, Sebastien; Martin, Julio; Martin, Fernando; Flandez, Jorge; Colado, Juan C

    2015-07-01

    Literature that provides progression models based on core muscle activity and postural manipulations is scarce. The purpose of this study was to investigate the core muscle activity in a series of balance exercises with different stability levels and additional elastic resistance. A descriptive study of electromyography (EMG) was performed with forty-four healthy subjects that completed 12 exercises in a random order. Exercises were performed unipedally or bipedally with or without elastic tubing as resistance on various unstable (uncontrolled multiaxial and uniaxial movement) and stable surfaces. Surface EMG on the lumbar multífidus spinae (LM), thoracic multífidus spinae (TM), lumbar erector spinae (LE), thoracic erector spinae (TE) and gluteus maximus (GM), on the dominant side of the body were collected to quantify the amount of muscle activity and were expressed as a % of the maximum voluntary isometric contraction (MVIC). Significant differences (pcore muscle activity. An adequate exercise progression based on global core EMG could start with seated positions, progressing to bipedal standing stance (i.e., from either multiaxial or stable surface to uniaxial surface). Following this, unipedal standing positions may be performed (i.e., from either multiaxial or stable surface to uniaxial surface) and finally, elastic resistance must be added in order to increase EMG levels (i.e., from stable surface progressing to any of the used unstable surfaces). Copyright © 2015 Elsevier B.V. All rights reserved.

  6. Puerperal Group A Streptococcal Infections: A Case Series and Discussion

    Directory of Open Access Journals (Sweden)

    Mary T. Busowski

    2013-01-01

    Full Text Available Puerperal group A streptococcal infections, a major postpartum killer during the late 19th and early 20th centuries, have become (fortunately rare. We describe a cluster of 4 serious peripartum group A streptococcal infections occurring within the past five years at a single medical center. These cases were not epidemiologically linked and serve to illustrate the continuing risk of these potentially fulminant infections.

  7. 一些特殊的p核p群%Some Special Core-p p-Groups

    Institute of Scientific and Technical Information of China (English)

    张军强; 任鹏飞

    2012-01-01

    In this paper, we investigate some special core-p p-groups, and give some examples of non-regular core-p p-groups.%给出了一些特殊的p核p群的分类,并给出了一些非正则p核p群的例子.

  8. Weyl Group Multiple Dirichlet Series Type A Combinatorial Theory (AM-175)

    CERN Document Server

    Brubaker, Ben; Friedberg, Solomon

    2011-01-01

    Weyl group multiple Dirichlet series are generalizations of the Riemann zeta function. Like the Riemann zeta function, they are Dirichlet series with analytic continuation and functional equations, having applications to analytic number theory. By contrast, these Weyl group multiple Dirichlet series may be functions of several complex variables and their groups of functional equations may be arbitrary finite Weyl groups. Furthermore, their coefficients are multiplicative up to roots of unity, generalizing the notion of Euler products. This book proves foundational results about these series an

  9. Biostatistics Series Module 3: Comparing Groups: Numerical Variables.

    Science.gov (United States)

    Hazra, Avijit; Gogtay, Nithya

    2016-01-01

    Numerical data that are normally distributed can be analyzed with parametric tests, that is, tests which are based on the parameters that define a normal distribution curve. If the distribution is uncertain, the data can be plotted as a normal probability plot and visually inspected, or tested for normality using one of a number of goodness of fit tests, such as the Kolmogorov-Smirnov test. The widely used Student's t-test has three variants. The one-sample t-test is used to assess if a sample mean (as an estimate of the population mean) differs significantly from a given population mean. The means of two independent samples may be compared for a statistically significant difference by the unpaired or independent samples t-test. If the data sets are related in some way, their means may be compared by the paired or dependent samples t-test. The t-test should not be used to compare the means of more than two groups. Although it is possible to compare groups in pairs, when there are more than two groups, this will increase the probability of a Type I error. The one-way analysis of variance (ANOVA) is employed to compare the means of three or more independent data sets that are normally distributed. Multiple measurements from the same set of subjects cannot be treated as separate, unrelated data sets. Comparison of means in such a situation requires repeated measures ANOVA. It is to be noted that while a multiple group comparison test such as ANOVA can point to a significant difference, it does not identify exactly between which two groups the difference lies. To do this, multiple group comparison needs to be followed up by an appropriate post hoc test. An example is the Tukey's honestly significant difference test following ANOVA. If the assumptions for parametric tests are not met, there are nonparametric alternatives for comparing data sets. These include Mann-Whitney U-test as the nonparametric counterpart of the unpaired Student's t-test, Wilcoxon signed-rank test

  10. On-line core monitoring system based on buckling corrected modified one group model

    Energy Technology Data Exchange (ETDEWEB)

    Freire, Fernando S., E-mail: freire@eletronuclear.gov.br [ELETROBRAS Eletronuclear Gerencia de Combustivel Nuclear, Rio de Janeiro, RJ (Brazil)

    2011-07-01

    Nuclear power reactors require core monitoring during plant operation. To provide safe, clean and reliable core continuously evaluate core conditions. Currently, the reactor core monitoring process is carried out by nuclear code systems that together with data from plant instrumentation, such as, thermocouples, ex-core detectors and fixed or moveable In-core detectors, can easily predict and monitor a variety of plant conditions. Typically, the standard nodal methods can be found on the heart of such nuclear monitoring code systems. However, standard nodal methods require large computer running times when compared with standards course-mesh finite difference schemes. Unfortunately, classic finite-difference models require a fine mesh reactor core representation. To override this unlikely model characteristic we can usually use the classic modified one group model to take some account for the main core neutronic behavior. In this model a course-mesh core representation can be easily evaluated with a crude treatment of thermal neutrons leakage. In this work, an improvement made on classic modified one group model based on a buckling thermal correction was used to obtain a fast, accurate and reliable core monitoring system methodology for future applications, providing a powerful tool for core monitoring process. (author)

  11. Biostatistics Series Module 4: Comparing Groups - Categorical Variables.

    Science.gov (United States)

    Hazra, Avijit; Gogtay, Nithya

    2016-01-01

    Categorical variables are commonly represented as counts or frequencies. For analysis, such data are conveniently arranged in contingency tables. Conventionally, such tables are designated as r × c tables, with r denoting number of rows and c denoting number of columns. The Chi-square (χ(2)) probability distribution is particularly useful in analyzing categorical variables. A number of tests yield test statistics that fit, at least approximately, a χ(2) distribution and hence are referred to as χ(2) tests. Examples include Pearson's χ(2) test (or simply the χ(2) test), McNemar's χ(2) test, Mantel-Haenszel χ(2) test and others. The Pearson's χ(2) test is the most commonly used test for assessing difference in distribution of a categorical variable between two or more independent groups. If the groups are ordered in some manner, the χ(2) test for trend should be used. The Fisher's exact probability test is a test of the independence between two dichotomous categorical variables. It provides a better alternative to the χ(2) statistic to assess the difference between two independent proportions when numbers are small, but cannot be applied to a contingency table larger than a two-dimensional one. The McNemar's χ(2) test assesses the difference between paired proportions. It is used when the frequencies in a 2 × 2 table represent paired samples or observations. The Cochran's Q test is a generalization of the McNemar's test that compares more than two related proportions. The P value from the χ(2) test or its counterparts does not indicate the strength of the difference or association between the categorical variables involved. This information can be obtained from the relative risk or the odds ratio statistic which is measures of dichotomous association obtained from 2 × 2 tables.

  12. Biostatistics series module 4: Comparing groups - categorical variables

    Directory of Open Access Journals (Sweden)

    Avijit Hazra

    2016-01-01

    Full Text Available Categorical variables are commonly represented as counts or frequencies. For analysis, such data are conveniently arranged in contingency tables. Conventionally, such tables are designated as r × c tables, with r denoting number of rows and c denoting number of columns. The Chi-square (χ2 probability distribution is particularly useful in analyzing categorical variables. A number of tests yield test statistics that fit, at least approximately, a χ2 distribution and hence are referred to as χ2 tests. Examples include Pearson′s χ2 test (or simply the χ2 test, McNemar′s χ2 test, Mantel-Haenszel χ2 test and others. The Pearson′s χ2 test is the most commonly used test for assessing difference in distribution of a categorical variable between two or more independent groups. If the groups are ordered in some manner, the χ2 test for trend should be used. The Fisher′s exact probability test is a test of the independence between two dichotomous categorical variables. It provides a better alternative to the χ2 statistic to assess the difference between two independent proportions when numbers are small, but cannot be applied to a contingency table larger than a two-dimensional one. The McNemar′s χ2 test assesses the difference between paired proportions. It is used when the frequencies in a 2 × 2 table represent paired samples or observations. The Cochran′s Q test is a generalization of the McNemar′s test that compares more than two related proportions. The P value from the χ2 test or its counterparts does not indicate the strength of the difference or association between the categorical variables involved. This information can be obtained from the relative risk or the odds ratio statistic which is measures of dichotomous association obtained from 2 × 2 tables.

  13. On a finite group having a normal series whose factors have bicyclic Sylow subgroups

    CERN Document Server

    Monakhov, V S

    2009-01-01

    We consider the structure of a finite groups having a normal series whose factors have bicyclic Sylow subgroups. In particular, we investigated groups of odd order and $A_4$-free groups with this property. Exact estimations of the derived length and nilpotent length of such groups are obtained.

  14. Lacunary Fourier Series and a Qualitative Uncertainty Principle for Compact Lie Groups

    Indian Academy of Sciences (India)

    E K Narayanan; A Sitaram

    2011-02-01

    We define lacunary Fourier series on a compact connected semisimple Lie group . If $f\\in L^1(G)$ has lacunary Fourier series and vanishes on a non empty open subset of , then we prove that vanishes identically. This result can be viewed as a qualitative uncertainty principle.

  15. Felder's elliptic quantum group and elliptic hypergeometric series on the root system A_n

    CERN Document Server

    Rosengren, Hjalmar

    2010-01-01

    We introduce a generalization of elliptic 6j-symbols, which can be interpreted as matrix elements for intertwiners between corepresentations of Felder's elliptic quantum group. For special parameter values, they can be expressed in terms of multivariable elliptic hypergeometric series related to the root system A_n. As a consequence, we obtain new biorthogonality relations for such series.

  16. Atlantic-Arctic exchange in a series of ocean model simulations (CORE-II)

    Science.gov (United States)

    Roth, Christina; Behrens, Erik; Biastoch, Arne

    2014-05-01

    In this study we aim to improve the understanding of exchange processes between the North Atlantic and the Arctic Ocean. The Nordic Sea builds an important connector between these regions, by receiving and modifying warm and saline Atlantic waters, and by providing dense overflow as a backbone of the Atlantic Meridional Overturning Circulation (AMOC). Using a hierarchy of global ocean/sea-ice models, the specific role of the Nordic Seas, both providing a feedback with the AMOC, but also as a modulator of the Atlantic water flowing into the Arctic Ocean, is examined. The models have been performed under the CORE-II protocol, in which atmospheric forcing of the past 60 years was applied in a subsequent series of 5 iterations. During the course of this 300-year long integration, the AMOC shows substantial changes, which are correlated with water mass characteristics in the Denmark Strait overflow characteristics. Quantitative analyses using Lagrangian trajectories explore the impact of these trends on the Arctic Ocean through the Barents Sea and the Fram Strait.

  17. Integral forms of Kac-Moody groups and Eisenstein series in low dimensional supergravity theories

    CERN Document Server

    Bao, Ling

    2013-01-01

    Kac-Moody groups $G$ over $\\mathbb{R}$ have been conjectured to occur as symmetry groups of supergravities in dimensions less than 3, and their integer forms $G(\\mathbb{Z})$ are conjecturally U-duality groups. Mathematical descriptions of $G(\\mathbb{Z})$, due to Tits, are functorial and not amenable to computation or applications. We construct Kac-Moody groups over $\\mathbb{R}$ and $\\mathbb{Z}$ using an analog of Chevalley's constructions in finite dimensions and Garland's constructions in the affine case. We extend a construction of Eisenstein series on finite dimensional semisimple algebraic groups using representation theory, which appeared in the context of superstring theory, to general Kac-Moody groups. This coincides with a generalization of Garland's Eisenstein series on affine Kac-Moody groups to general Kac-Moody groups and includes Eisenstein series on $E_{10}$ and $E_{11}$. For finite dimensional groups, Eisenstein series encode the quantum corrections in string theory and supergravity theories. T...

  18. Eisenstein series for higher-rank groups and string theory amplitudes

    CERN Document Server

    Green, Michael B; Russo, Jorge G; Vanhove, Pierre

    2010-01-01

    Scattering amplitudes of superstring theory are strongly constrained by the requirement that they be invariant under dualities generated by discrete subgroups, E_n(Z), of simply-laced Lie groups in the E_n series (n<= 8). In particular, expanding the four-supergraviton amplitude at low energy gives a series of higher derivative corrections to Einstein's theory, with coefficients that are automorphic functions with a rich dependence on the moduli. Boundary conditions supplied by string and supergravity perturbation theory, together with a chain of relations between successive groups in the E_n series, constrain the constant terms of these coefficients in three distinct parabolic subgroups. Using this information we are able to determine the expressions for the first two higher derivative interactions (which are BPS-protected) in terms of specific Eisenstein series. Further, we determine key features of the coefficient of the third term in the low energy expansion of the four-supergraviton amplitude (which i...

  19. A Four Group Reference Code for Solving Neutron Diffusion Equation in a VVER-440 Core

    Energy Technology Data Exchange (ETDEWEB)

    Saarinen, Simo [Fortum Nuclear Services Ltd., P.O. Box 100, 00048 Fortum (Finland)

    2008-07-01

    Nuclear reactor core power calculation is essential in the analysis of the nuclear power plant and especially the core. Currently, the core power distribution in Loviisa VVER-440 core is calculated using nodal code HEXBU-3D and pin-power reconstruction code ELSI-1440 that solve the two group neutron diffusion equation. The computer power available has increased significantly during the last decades allowing us to develop a fine mesh code HEXRE for solving the four group diffusion equation. The diffusion equations are discretized using piecewise linear polynomials. The core is discretized using one node per fuel pin cell. The axial discretization can be chosen freely. The boundary conditions are described using diffusion theory and albedos. Burnup dependence is modelled by tabulating diffusion parameters at certain burnup values and using interpolation for the intermediate values. A two degree polynomial is used for the modelling of the feedback effects. Eigenvalue calculation for both boron concentration and multiplication factor control has been formulated. A possibility to perform fuel loading and shuffling operations is implemented. HEXRE has been thoroughly compared with HEXBU-3D and ELSI-1440. The effect of the different energy and space discretizations used is investigated. Some safety criteria for the core calculated with the HEXRE and HEXBU-3D/ELSI-1440 have been compared. From the calculations (e.g. the safety criteria) we can estimate whether there exists systematic deviations in HEXBU- 3D/ELSI-1440 calculations or not. (author)

  20. Littelmann patterns and Weyl group multiple Dirichlet series of type D

    CERN Document Server

    Chinta, Gautam

    2009-01-01

    We formulate a conjecture for the local parts of Weyl group multiple Dirichlet series attached to root systems of type D. Our conjecture is analogous to the description of the local parts of type A series given by Brubaker, Bump, Friedberg, and Hoffstein in terms of Gelfand--Tsetlin patterns. Our conjecture is given in terms of patterns for irreducible representations of even orthogonal Lie algebras developed by Littelmann.

  1. ESO 3060170: A massive fossil galaxy group with a heated gas core?

    DEFF Research Database (Denmark)

    Sun, M.; Forman, W.; Vikhlinin, A.

    2004-01-01

    We present a detailed study of the ESO 3060170 galaxy group, combining Chandra, XMM-Newton, and optical observations. The system is found to be a fossil galaxy group. The group X-ray emission is composed of a central, dense, cool core (10 kpc in radius) and an isothermal medium beyond the central...... 10 kpc. The region between 10 and 50 kpc (the cooling radius) has the same temperature as the gas from 50 to 400 kpc, although the gas cooling time between 10 and 50 kpc (2-6 Gyr) is shorter than the Hubble time. Thus, the ESO 3060170 group does not have a group-sized cooling core. We suggest...

  2. ZTE Partners with KPN Group Belgium to Deploy Packet-Switched Core Network

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    27 August 2012--ZTE Corporation has signed a deal on a packet-switched core network (CN) for KPN Group Belgium (KPNGB). KPNGB will deploy ZTE's packet-switched CN equipment, which supports unified radio access. The contract is the second of its kind between ZTE and KPNfollows from a construction project with KPN Germany (E-Plus) that was completed in September 2010.

  3. The high resolution vacuum ultraviolet absorption spectra of the group VI dihydrides and deuterides Rydberg series

    CERN Document Server

    Mayhew, C A

    1984-01-01

    The high resolution absorption spectra of the important group VI dihydrides and deuterides in the vacuum ultraviolet below, and up to, their first ionisation potentials are presented. These spectra were recorded using synchrotron radiation as the background light source in conjunction with a 3m normal incidence vacuum spectrograph, equipped with holographic gratings. Due to the nature of the originating orbital for the majority of optical transitions in the VUV well developed Rydberg series are observed. One particular series can be followed up to fairly high n, so that accurate values of the first ionisation potential are determined. The identifications of the Rydberg series are made from arguments relating to their oscillator strengths, quantum defects, symmetries and from comparisons with the spectra of the corresponding united atoms i.e. the inert gases. Examples of the symmetry assignments for Rydberg series from rotational band contour analyses of the lower Rydberg members for the H sub 2 S, H sub 2 Se ...

  4. Progress Report on the Airborne Metadata and Time Series Working Groups of the 2016 ESDSWG

    Science.gov (United States)

    Evans, K. D.; Northup, E. A.; Chen, G.; Conover, H.; Ames, D. P.; Teng, W. L.; Olding, S. W.; Krotkov, N. A.

    2016-12-01

    NASA's Earth Science Data Systems Working Groups (ESDSWG) was created over 10 years ago. The role of the ESDSWG is to make recommendations relevant to NASA's Earth science data systems from users' experiences. Each group works independently focusing on a unique topic. Participation in ESDSWG groups comes from a variety of NASA-funded science and technology projects, including MEaSUREs and ROSS. Participants include NASA information technology experts, affiliated contractor staff and other interested community members from academia and industry. Recommendations from the ESDSWG groups will enhance NASA's efforts to develop long term data products. The Airborne Metadata Working Group is evaluating the suitability of the current Common Metadata Repository (CMR) and Unified Metadata Model (UMM) for airborne data sets and to develop new recommendations as necessary. The overarching goal is to enhance the usability, interoperability, discovery and distribution of airborne observational data sets. This will be done by assessing the suitability (gaps) of the current UMM model for airborne data using lessons learned from current and past field campaigns, listening to user needs and community recommendations and assessing the suitability of ISO metadata and other standards to fill the gaps. The Time Series Working Group (TSWG) is a continuation of the 2015 Time Series/WaterML2 Working Group. The TSWG is using a case study-driven approach to test the new Open Geospatial Consortium (OGC) TimeseriesML standard to determine any deficiencies with respect to its ability to fully describe and encode NASA earth observation-derived time series data. To do this, the time series working group is engaging with the OGC TimeseriesML Standards Working Group (SWG) regarding unsatisfied needs and possible solutions. The effort will end with the drafting of an OGC Engineering Report based on the use cases and interactions with the OGC TimeseriesML SWG. Progress towards finalizing

  5. Selectivity of peptide bond dissociation on excitation of a core electron: Effects of a phenyl group

    Science.gov (United States)

    Tsai, Cheng-Cheng; Chen, Jien-Lian; Hu, Wei-Ping; Lin, Yi-Shiue; Lin, Huei-Ru; Lee, Tsai-Yun; Lee, Yuan T.; Ni, Chi-Kung; Liu, Chen-Lin

    2016-09-01

    The selective dissociation of a peptide bond upon excitation of a core electron in acetanilide and N-benzylacetamide was investigated. The total-ion-yield near-edge X-ray absorption fine structure spectra were recorded and compared with the predictions from time-dependent density functional theory. The branching ratios for the dissociation of a peptide bond are observed as 16-34% which is quite significant. This study explores the core-excitation, the X-ray photodissociation pathways, and the theoretical explanation of the NEXAFS spectra of organic molecules containing both a peptide bond and a phenyl group.

  6. Challenges to validity in single-group interrupted time series analysis.

    Science.gov (United States)

    Linden, Ariel

    2017-04-01

    Single-group interrupted time series analysis (ITSA) is a popular evaluation methodology in which a single unit of observation is studied; the outcome variable is serially ordered as a time series, and the intervention is expected to "interrupt" the level and/or trend of the time series, subsequent to its introduction. The most common threat to validity is history-the possibility that some other event caused the observed effect in the time series. Although history limits the ability to draw causal inferences from single ITSA models, it can be controlled for by using a comparable control group to serve as the counterfactual. Time series data from 2 natural experiments (effect of Florida's 2000 repeal of its motorcycle helmet law on motorcycle fatalities and California's 1988 Proposition 99 to reduce cigarette sales) are used to illustrate how history biases results of single-group ITSA results-as opposed to when that group's results are contrasted to those of a comparable control group. In the first example, an external event occurring at the same time as the helmet repeal appeared to be the cause of a rise in motorcycle deaths, but was only revealed when Florida was contrasted with comparable control states. Conversely, in the second example, a decreasing trend in cigarette sales prior to the intervention raised question about a treatment effect attributed to Proposition 99, but was reinforced when California was contrasted with comparable control states. Results of single-group ITSA should be considered preliminary, and interpreted with caution, until a more robust study design can be implemented. © 2016 John Wiley & Sons, Ltd.

  7. Characterisation of Alternaria species-groups associated with core rot of apples in South Africa

    DEFF Research Database (Denmark)

    Serdani, M.; Kang, J.C.; Andersen, Birgitte

    2002-01-01

    Alternaria core rot of red apple cultivars is a serious post-harvest disease in South Africa. Thirty isolates of Alternaria spp. previously isolated from apple, together with reference isolates of A. alternata and A. infectoria, were characterised and grouped according to their sporulation patterns...... and conidial morphology. Isolates were identified as belonging to A. arborescens, A. infectoria and A. tenuissima species-groups. The isolates were also analysed for production of mycotoxins and other secondary metabolites and their cultural characteristics on DRYES medium were recorded. Apple fruit were...... the other species-groups, as all isolates had a distinction of 35 base pair insertions and 6 base pair deletions in the ITS regions. The results obtained in the present study showed that the major pathogens associated with core rot disease of Top Red apples in South Africa belong to the A. tenuissima...

  8. Using machine learning to identify structural breaks in single-group interrupted time series designs.

    Science.gov (United States)

    Linden, Ariel; Yarnold, Paul R

    2016-12-01

    Single-group interrupted time series analysis (ITSA) is a popular evaluation methodology in which a single unit of observation is being studied, the outcome variable is serially ordered as a time series and the intervention is expected to 'interrupt' the level and/or trend of the time series, subsequent to its introduction. Given that the internal validity of the design rests on the premise that the interruption in the time series is associated with the introduction of the treatment, treatment effects may seem less plausible if a parallel trend already exists in the time series prior to the actual intervention. Thus, sensitivity analyses should focus on detecting structural breaks in the time series before the intervention. In this paper, we introduce a machine-learning algorithm called optimal discriminant analysis (ODA) as an approach to determine if structural breaks can be identified in years prior to the initiation of the intervention, using data from California's 1988 voter-initiated Proposition 99 to reduce smoking rates. The ODA analysis indicates that numerous structural breaks occurred prior to the actual initiation of Proposition 99 in 1989, including perfect structural breaks in 1983 and 1985, thereby casting doubt on the validity of treatment effects estimated for the actual intervention when using a single-group ITSA design. Given the widespread use of ITSA for evaluating observational data and the increasing use of machine-learning techniques in traditional research, we recommend that structural break sensitivity analysis is routinely incorporated in all research using the single-group ITSA design. © 2016 John Wiley & Sons, Ltd.

  9. ESO 3060170: A massive fossil galaxy group with a heated gas core?

    DEFF Research Database (Denmark)

    Sun, M.; Forman, W.; Vikhlinin, A.

    2004-01-01

    .85). This is direct evidence of the importance of nongravitational processes in group centers. We derive the mass profiles within 1/3r(vir) and find that the ESO 3060170 group is the most massive fossil group known [(1-2)x10(14) M-circle dot]. The M/L ratio of the system, similar to150 at 0.3r(vir), is normal.......We present a detailed study of the ESO 3060170 galaxy group, combining Chandra, XMM-Newton, and optical observations. The system is found to be a fossil galaxy group. The group X-ray emission is composed of a central, dense, cool core (10 kpc in radius) and an isothermal medium beyond the central...

  10. A core origin for group IVA iron meteorites - A reply to Moren and Goldstein

    Science.gov (United States)

    Willis, J.; Wasson, J. T.

    1978-01-01

    Because uncertainties in experimental data are large, one has considerable latitude in choosing the input parameters needed to calculate iron meteorite cooling rates. The best way to test input parameters is by examining their ability to yield the observed properties of the meteorites. Our phase diagram yields fits to kamacite profiles that are superior to those based on the Moren-Goldstein phase diagram. Our method of allowing for the effect of P on the Ni diffusion coefficient takes into account the enhancement in this effect with decreasing temperature; Moren and Goldstein use a relationship derived for a temperature of 1100 C, well outside the 700-350 C range where kamacite growth occurs. Use of our input parameters yields cooling rates in IVA irons that are independent of composition, consistent with a core origin. Since the fractionation of siderophiles in group IVA also indicates a core origin, we conclude that this is the correct model for this group.

  11. Glycolipid core structure switching from globo- to lacto- and ganglio-series during retinoic acid-induced differentiation of TERA-2-derived human embryonal carcinoma cells.

    Science.gov (United States)

    Fenderson, B A; Andrews, P W; Nudelman, E; Clausen, H; Hakomori, S

    1987-07-01

    We have analyzed the glycolipid markers of a recently cloned human embryonal carcinoma (EC) cell line, NTERA-2, which differentiates extensively into a variety of somatic cell types when exposed to retinoic acid. These tumor cells provide a model system that can be used to study the ontogeny of glycolipid diversity during human embryonic development. Glycolipid antigens were identified by cell surface immunofluorescence and thin-layer chromatography immunostaining using a comprehensive set of anticarbohydrate monoclonal antibodies. Undifferentiated NTERA-2 cells were found to express predominantly globo-series glycolipids, including Gb3, Gb5 (IV3GalGb4), globo-ganglioside (IV3NeuAc alpha 2----3GalGb4), globo-H (IV3Fuc alpha 1----2GalGb4), and globo-A (IV3GalNAc alpha 1----3[Fuc alpha 1----2]GalGb4). When NTERA-2 cells were induced to differentiate by culturing in the presence of 10(-5) M retinoic acid, a remarkable shift of cellular glycolipids from globo-series to lacto- and ganglio-series was observed: Globo-series structures declined, particularly during the period 7-20 days after first exposure to retinoic acid, while lacto-series structures, including fucosyl alpha 1----3 type 2 chain (Lex) and sialosyl type 2 chain, and ganglio-series structures, including GM3, GD3, 9-O-acetyl-GD3, GM2, GD2, and GT3, increased. The presence of globo-A and globo-H as the major ABH blood group antigens in undifferentiated NTERA-2 cells suggests that globo-series blood group antigens are embryonic antigens, synthesis of which switches to lacto-series during human development. Two-color immunofluorescence analysis indicated preferential expression of several ganglio- and lacto-series antigens on different subsets of differentiated cells and permitted the relationship of these subsets to the development of neurons in NTERA-2 cultures to be determined. The results suggest that glycosyltransferase, particularly those involved in controlling glycoconjugate core structure assembly

  12. The Hard-Core Unemployed, An Annotated Bibliography. Reference Memorandum Series.

    Science.gov (United States)

    Mesics, Emil, Comp.; Marcus, Samuel, Comp.

    Pertinent items having to do with national policy on hard-core unemployed and specific applications and techniques drawn from organizational experiences are identified. The compilers focused upon 1968 publications; the earliest publication date is 1964. The 41 entries are organized under the following headings: (1) Poverty in the Community and the…

  13. CORE

    DEFF Research Database (Denmark)

    Krigslund, Jeppe; Hansen, Jonas; Hundebøll, Martin

    2013-01-01

    different flows. Instead of maintaining these approaches separate, we propose a protocol (CORE) that brings together these coding mechanisms. Our protocol uses random linear network coding (RLNC) for intra- session coding but allows nodes in the network to setup inter- session coding regions where flows...... intersect. Routes for unicast sessions are agnostic to other sessions and setup beforehand, CORE will then discover and exploit intersecting routes. Our approach allows the inter-session regions to leverage RLNC to compensate for losses or failures in the overhearing or transmitting process. Thus, we...... increase the benefits of XORing by exploiting the underlying RLNC structure of individual flows. This goes beyond providing additional reliability to each individual session and beyond exploiting coding opportunistically. Our numerical results show that CORE outperforms both forwarding and COPE...

  14. CORE

    DEFF Research Database (Denmark)

    Krigslund, Jeppe; Hansen, Jonas; Hundebøll, Martin

    2013-01-01

    different flows. Instead of maintaining these approaches separate, we propose a protocol (CORE) that brings together these coding mechanisms. Our protocol uses random linear network coding (RLNC) for intra- session coding but allows nodes in the network to setup inter- session coding regions where flows...... intersect. Routes for unicast sessions are agnostic to other sessions and setup beforehand, CORE will then discover and exploit intersecting routes. Our approach allows the inter-session regions to leverage RLNC to compensate for losses or failures in the overhearing or transmitting process. Thus, we...... increase the benefits of XORing by exploiting the underlying RLNC structure of individual flows. This goes beyond providing additional reliability to each individual session and beyond exploiting coding opportunistically. Our numerical results show that CORE outperforms both forwarding and COPE...

  15. A Fourier series approach for comparing groups of subjects on ambulatory blood pressure patterns.

    Science.gov (United States)

    Somes, G W; Harshfield, G A; Arheart, K L; Miller, S T

    1994-06-30

    We develop an approach to the statistical analysis of 24-hour ambulatory blood pressure monitoring where we represent each subject's profile by a different mathematical model. We first smooth the data and then use a Fourier series approach to determine the best model for each subject. We then estimate summary variables based on each subject's model to compare distinct groups of subjects. In comparing 15 adult black male hypertensives to eight adult black male normotensives we found that the two groups differ on the shift away from the mesor for both the systolic and the diastolic blood pressure profile.

  16. Practitioner perspectives from seven health professional groups on core competencies in the context of chronic care.

    Science.gov (United States)

    Fouche, Christa; Kenealy, Timothy; Mace, Jennifer; Shaw, John

    2014-11-01

    The prevalence of chronic illness is growing worldwide and management is increasingly undertaken by interprofessional teams, yet education is still generally provided in separate professions. The aim of this study was to explore the perspectives of New Zealand healthcare practitioners from seven professional groups involved in chronic care (general practice medicine, nursing, occupational therapy, pharmacy, physiotherapy, social work, and speech language therapy) on the core competencies required of those working in this area. The study was set in the context of the chronic care and shared decision-making (SDM) models. The core competencies for chronic care practitioners proposed by the World Health Organisation were used to shape the research questions. Focus groups with expert clinicians (n = 20) and semi-structured interviews with practitioners (n = 32) were undertaken. Findings indicated a high level of agreement that the core competencies were appropriate and relevant for chronic care practitioners but that many educational and practice gaps existed and interprofessional education in New Zealand was not currently addressing these gaps. Among the key issues highlighted for attention by educators and policy-makers were the following: teams and teamwork, professional roles and responsibilities, interprofessional communication, cultural competence, better engagement with patients, families, and carers, and common systems, information sharing and confidentiality.

  17. Size of the group IVA iron meteorite core: Constraints from the age and composition of Muonionalusta

    CERN Document Server

    Moskovitz, Nicholas A

    2011-01-01

    The group IVA fractionally crystallized iron meteorites display a diverse range of metallographic cooling rates. These have been attributed to their formation in a metallic core, approximately 150 km in radius, that cooled to crystallization in the absence of any appreciable insulating mantle. Here we build upon this formation model by incorporating several new constraints. These include (i) a recent U-Pb radiometric closure age of <2.5 Myr after solar system formation for the group IVA iron Muonionalusta, (ii) new measurements and modeling of highly siderophile element compositions for a suite of IVAs, and (iii) consideration of the thermal effects of heating by the decay of the short-lived radionuclide 60Fe. Our model for the thermal evolution of the IVA core suggests that it was approximately 50 - 110 km in radius after being collisionally exposed. This range is due to uncertainties in the initial abundance of live 60Fe incorporated into the IVA core. Our models define a relationship between cooling rat...

  18. Patch test results with the metalworking fluid series of the German Contact Dermatitis Research Group (DKG).

    Science.gov (United States)

    Geier, Johannes; Lessmann, Holger; Dickel, Heinrich; Frosch, Peter J; Koch, Patrick; Becker, Detlef; Jappe, Uta; Aberer, Werner; Schnuch, Axel; Uter, Wolfgang

    2004-09-01

    Based on the information of the interdisciplinary task force on allergy diagnostics in the metal branch, in 2001, the German Contact Dermatitis Research Group (DKG) compiled two metalworking fluid (MWF) test series with currently and previously used components, respectively. After 2 years of patch testing, we present results obtained with these series, based on data of the Information Network of Departments of Dermatology (IVDK). 251 metalworkers who were patch tested because of suspected MWF dermatitis in 2002 and 2003 were included in this retrospective data analysis. Of these, 206 were tested with the current MWF series and 155 with the historical MWF series. Among the current MWF allergens, monoethanolamine ranked 1st with 11.6% positive reactions. Diethanolamine (3.0%), triethanolamine (1.1%), and diglycolamine (1.9%) elicited positive reactions far less frequently. Allergic reactions to p-aminoazobenzene were frequently observed (6.0%), but the relevance of these reactions is still obscure. Positive reactions to biocides ranged from 4.5% for Bioban CS 1135 to 0.5% for iodopropynyl butylcarbamate and 2-phenoxyethanol. Concomitant reactions to formaldehyde, which caused positive reactions in 3.3%, and formaldehyde releasers occurred to varying extents without conclusive pattern. No positive reactions were seen to dibutyl phthalate, di-2-ethylhexyl phthalate, tricresyl phosphate, isopropyl myristate or benzotriazole. With the historical MWF test series, positive reactions to methyldibromo glutaronitrile (MDBGN) were observed most frequently. However, sensitization via allergen sources other than MWF seems likely, as MDBGN, during the study period, has been one of the most frequent preservative allergens in cosmetics and body care products. Other historical MWF allergens comprised morpholinyl mercaptobenzothiazole (3.3%), benzisothiazolinone (BIT; 2.0%) and Bioban P 1487(1.3%). BIT is currently used in MWF again, so it was shifted to the current MWF test series

  19. Relative stability of core groups in pollination networks in a biodiversity hotspot over four years.

    Directory of Open Access Journals (Sweden)

    Qiang Fang

    Full Text Available Plants and their pollinators form pollination networks integral to the evolution and persistence of species in communities. Previous studies suggest that pollination network structure remains nested while network composition is highly dynamic. However, little is known about temporal variation in the structure and function of plant-pollinator networks, especially in species-rich communities where the strength of pollinator competition is predicted to be high. Here we quantify temporal variation of pollination networks over four consecutive years in an alpine meadow in the Hengduan Mountains biodiversity hotspot in China. We found that ranked positions and idiosyncratic temperatures of both plants and pollinators were more conservative between consecutive years than in non-consecutive years. Although network compositions exhibited high turnover, generalized core groups--decomposed by a k-core algorithm--were much more stable than peripheral groups. Given the high rate of turnover observed, we suggest that identical plants and pollinators that persist for at least two successive years sustain pollination services at the community level. Our data do not support theoretical predictions of a high proportion of specialized links within species-rich communities. Plants were relatively specialized, exhibiting less variability in pollinator composition at pollinator functional group level than at the species level. Both specialized and generalized plants experienced narrow variation in functional pollinator groups. The dynamic nature of pollination networks in the alpine meadow demonstrates the potential for networks to mitigate the effects of fluctuations in species composition in a high biodiversity area.

  20. A Preliminary Core Domain Set for Clinical Trials of Shoulder Disorders: A Report from the OMERACT 2016 Shoulder Core Outcome Set Special Interest Group.

    Science.gov (United States)

    Buchbinder, Rachelle; Page, Matthew J; Huang, Hsiaomin; Verhagen, Arianne P; Beaton, Dorcas; Kopkow, Christian; Lenza, Mario; Jain, Nitin B; Richards, Bethan; Richards, Pamela; Voshaar, Marieke; van der Windt, Danielle; Gagnier, Joel J

    2017-01-15

    The Outcome Measures in Rheumatology (OMERACT) Shoulder Core Outcome Set Special Interest Group (SIG) was established to develop a core outcome set (COS) for clinical trials of shoulder disorders. In preparation for OMERACT 2016, we systematically examined all outcome domains and measurement instruments reported in 409 randomized trials of interventions for shoulder disorders published between 1954 and 2015. Informed by these data, we conducted an international Delphi consensus study including shoulder trial experts, clinicians, and patients to identify key domains that should be included in a shoulder disorder COS. Findings were discussed at a stakeholder premeeting of OMERACT. At OMERACT 2016, we sought consensus on a preliminary core domain set and input into next steps. There were 13 and 15 participants at the premeeting and the OMERACT 2016 SIG meeting, respectively (9 attended both meetings). Consensus was reached on a preliminary core domain set consisting of an inner core of 4 domains: pain, physical function/activity, global perceived effect, and adverse events including death. A middle core consisted of 3 domains: emotional well-being, sleep, and participation (recreation and work). An outer core of research required to inform the final COS was also formulated. Our next steps are to (1) analyze whether participation (recreation and work) should be in the inner core, (2) conduct a third Delphi round to finalize definitions and wording of domains and reach final endorsement for the domains, and (3) determine which instruments fulfill the OMERACT criteria for measuring each domain.

  1. Core competencies for shared decision making training programs: insights from an international, interdisciplinary working group.

    Science.gov (United States)

    Légaré, France; Moumjid-Ferdjaoui, Nora; Drolet, Renée; Stacey, Dawn; Härter, Martin; Bastian, Hilda; Beaulieu, Marie-Dominique; Borduas, Francine; Charles, Cathy; Coulter, Angela; Desroches, Sophie; Friedrich, Gwendolyn; Gafni, Amiram; Graham, Ian D; Labrecque, Michel; LeBlanc, Annie; Légaré, Jean; Politi, Mary; Sargeant, Joan; Thomson, Richard

    2013-01-01

    Shared decision making is now making inroads in health care professionals' continuing education curriculum, but there is no consensus on what core competencies are required by clinicians for effectively involving patients in health-related decisions. Ready-made programs for training clinicians in shared decision making are in high demand, but existing programs vary widely in their theoretical foundations, length, and content. An international, interdisciplinary group of 25 individuals met in 2012 to discuss theoretical approaches to making health-related decisions, compare notes on existing programs, take stock of stakeholders concerns, and deliberate on core competencies. This article summarizes the results of those discussions. Some participants believed that existing models already provide a sufficient conceptual basis for developing and implementing shared decision making competency-based training programs on a wide scale. Others argued that this would be premature as there is still no consensus on the definition of shared decision making or sufficient evidence to recommend specific competencies for implementing shared decision making. However, all participants agreed that there were 2 broad types of competencies that clinicians need for implementing shared decision making: relational competencies and risk communication competencies. Further multidisciplinary research could broaden and deepen our understanding of core competencies for shared decision making training.

  2. The Character of the Principal Series of Representations of the Real Unimodular Group

    OpenAIRE

    Basu, Debabrata

    2001-01-01

    The character of the principal series of representations of SL(n,R) is evaluated by using Gel'fand and Naimark's definition of character. This representation is realized in the space of functions defined on the right coset space of SL(n,R) with respect to the subgroup of real triangular matrices. This form of the representations considerably simplifies the problem of determination of the integral kernel of the group ring which is fundamental in the Gel'fand-Naimark theory of character. An imp...

  3. The effect of core stability training on balance and mobility in ambulant individuals with multiple sclerosis: a multi-centre series of single case studies.

    Science.gov (United States)

    Freeman, J A; Gear, M; Pauli, A; Cowan, P; Finnigan, C; Hunter, H; Mobberley, C; Nock, A; Sims, R; Thain, J

    2010-11-01

    Core stability training is popular in the management of people with multiple sclerosis (MS); however, scientific evidence to support its effectiveness is scarce. To explore the effectiveness of core stability training on balance and mobility. A multi-centre series of eight single case studies was undertaken. Eight ambulant individuals with stable MS participated in 16 face-to-face core stability training sessions, delivered by a neurophysiotherapist, plus a daily home exercise programme. A range of outcomes were measured: 10-m timed walk, 12-item MS walking scale, timed get up and go, functional reach tests, timed single leg stance, visual analogue scales of two activities, and the Activities-specific Balance Confidence Scale. Visual analysis of trend, level and slope demonstrated improvement in five subjects (62%) in seven measures. This was confirmed by the two standard deviation band method of analysis for six measures. Analysis of group data (repeated measures within subjects analysis of variance) indicated significant improvement between baseline and intervention phases for timed walk (p = 0.019), MSWS-12 Scale (p = 0.041), forward (p = 0.015) and lateral reach (p = 0.012). In general, no further improvements were made following withdrawal of the intervention. This study provides preliminary evidence of the effectiveness of an 8-week core stability training programme in improving balance and mobility in ambulant people with MS. Variations in response to intervention are evident. Assessor-blinded randomized controlled studies are required to confirm these findings and determine patient characteristics which identify those who benefit most from this intervention.

  4. Genetic variation of maturity groups and four E genes in the Chinese soybean mini core collection

    Science.gov (United States)

    Huang, Xinyang; Zhou, Jing; Zeng, Haiyan; Sun, Shi; Jia, Hongchang; Li, Wenbin; Zhou, Xinan; Li, Suzhen; Chen, Pengyin; Wu, Cunxiang; Guo, Yong; Han, Tianfu; Qiu, Lijuan

    2017-01-01

    The mini core collection (MCC) has been established by streamlining core collection (CC) chosen from China National Genebank including 23,587 soybean (Glycine max) accessions by morphological traits and simple sequence repeat (SSR) markers. Few studies have been focused on the maturity that has been considered as one of the most critical traits for the determination of the adaptation-growing region of the soybean. In the current study, two hundred and ninty-nine accessions of MCC planted for two years at four locations namely in Heihe, Harbin, Jining and Wuhan cities in China were used to assess the variation of maturity in MCC and identify the integrated effect of 4 E loci on flowering and maturity time in soybean. Forty-two North American varieties served as references of maturity groups (MG). Each accession in MCC was classified by comparing with the MG references in the days from VE (emergence) and physiological maturity (R7). The results showed that MCC covered a large range of MGs from MG000 to MGIX/X. Original locations and sowing types were revealed as the major affecting factors for maturity groups of the MCC accessions. The ratio of the reproductive period to the vegetative period (R/V) varied among MCC accessions. Genotyping of 4 maturity genes (i.e. E1, E2, E3 and E4) in 228 accessions indicated that recessive alleles e1, e2, e3 and e4 promoted earlier flowering and shortened the maturity time with different effects, while the dominate alleles were always detected in accessions with longer maturity. The allelic combinations determined the diversification of soybean maturity groups and adaptation to different regions. Our results indicated that the maturity of Chinese soybean MCC showed genetic diversities in phenotype and genotype, which provided information for further MG classification, geographic adaptation analysis of Chinese soybean cultivars, as well as developing new soybean varieties with adaptation to specific regions. PMID:28207889

  5. A New Calibrated Sunspot Group Series Since 1749: Statistics of Active Day Fractions

    CERN Document Server

    Usoskin, I G; Lockwood, M; Mursula, K; Owens, M; Solanki, S K

    2015-01-01

    Although the sunspot-number series have existed since the mid-19th century, they are still the subject of intense debate, with the largest uncertainty being related to the "calibration" of the visual acuity of individual observers in the past. Daisy-chain regression methods are applied to inter-calibrate the observers which may lead to significant bias and error accumulation. Here we present a novel method to calibrate the visual acuity of the key observers to the reference data set of Royal Greenwich Observatory sunspot groups for the period 1900-1976, using the statistics of the active-day fraction. For each observer we independently evaluate their observational thresholds [S_S] defined such that the observer is assumed to miss all of the groups with an area smaller than S_S and report all the groups larger than S_S. Next, using a Monte-Carlo method we construct, from the reference data set, a correction matrix for each observer. The correction matrices are significantly non-linear and cannot be approximate...

  6. Manufacturing Phenomena or Preserving Phenomena? Core Issues in the Identification of Peer Social Groups with Social Cognitive Mapping Procedures

    Science.gov (United States)

    Farmer, Thomas W.; Xie, Hongling

    2013-01-01

    In this commentary on the "Multiple Meanings of Peer Groups in Social Cognitive Mapping," Thomas W. Farmer and Hongling Xie discuss core issues in the identification of peer social groups in natural settings using the social cognitive mapping (SCM) procedures. Farmer and Xie applaud the authors for their efforts to advance the study of…

  7. Manufacturing Phenomena or Preserving Phenomena? Core Issues in the Identification of Peer Social Groups with Social Cognitive Mapping Procedures

    Science.gov (United States)

    Farmer, Thomas W.; Xie, Hongling

    2013-01-01

    In this commentary on the "Multiple Meanings of Peer Groups in Social Cognitive Mapping," Thomas W. Farmer and Hongling Xie discuss core issues in the identification of peer social groups in natural settings using the social cognitive mapping (SCM) procedures. Farmer and Xie applaud the authors for their efforts to advance the study of…

  8. A 17-billion-solar-mass black hole in a group galaxy with a diffuse core.

    Science.gov (United States)

    Thomas, Jens; Ma, Chung-Pei; McConnell, Nicholas J; Greene, Jenny E; Blakeslee, John P; Janish, Ryan

    2016-04-21

    Quasars are associated with and powered by the accretion of material onto massive black holes; the detection of highly luminous quasars with redshifts greater than z = 6 suggests that black holes of up to ten billion solar masses already existed 13 billion years ago. Two possible present-day 'dormant' descendants of this population of 'active' black holes have been found in the galaxies NGC 3842 and NGC 4889 at the centres of the Leo and Coma galaxy clusters, which together form the central region of the Great Wall--the largest local structure of galaxies. The most luminous quasars, however, are not confined to such high-density regions of the early Universe; yet dormant black holes of this high mass have not yet been found outside of modern-day rich clusters. Here we report observations of the stellar velocity distribution in the galaxy NGC 1600--a relatively isolated elliptical galaxy near the centre of a galaxy group at a distance of 64 megaparsecs from Earth. We use orbit superposition models to determine that the black hole at the centre of NGC 1600 has a mass of 17 billion solar masses. The spatial distribution of stars near the centre of NGC 1600 is rather diffuse. We find that the region of depleted stellar density in the cores of massive elliptical galaxies extends over the same radius as the gravitational sphere of influence of the central black holes, and interpret this as the dynamical imprint of the black holes.

  9. Gas Sloshing and Radio Galaxy Dynamics in the Core of the 3C 449 Group

    Science.gov (United States)

    Lal, Dharam V.; Kraft, Ralph P.; Randall, Scott W.; Forman, William R.; Nulsen, Paul E.; Roediger, Elke; ZuHone, John A.; Hardcastle, Martin J.; Jones, Christine; Croston, Judith H.

    2013-01-01

    We present results from a 140 ks Chandra/ACIS-S observation of the hot gas around the canonical FR I radio galaxy 3C 449. An earlier, shorter 30 ks Chandra observation of the group gas showed an unusual entropy distribution and a surface brightness edge in the gas that could be a strong shock around the inner radio lobes. In our deeper data we find no evidence for a temperature increase inside of the brightness edge, but a temperature decrease across part of the edge. This suggests that the edge is a "sloshing" cold front due to a merger within the last 1.3-1.6 Gyr. Both the northern and southern inner jets are bent slightly to the west in projection as they enter their respective lobes, suggesting that the sloshing core is moving to the east. The straight inner jet flares at approximately the position where it crosses the contact edge, suggesting that the jet is entraining and thermalizing some of the hot gas as it crosses the edge.We also detect filaments of X-ray emission around the southern inner radio jet and lobe which we attribute to low entropy entrained gas. The lobe flaring and gas entrainment were originally predicted in simulations of Loken et al. and are confirmed in our deep observation.

  10. The European standard series. European Environmental and Contact Dermatitis Research Group (EECDRG)

    DEFF Research Database (Denmark)

    Bruynzeel, D P; Andersen, Klaus Ejner; Camarasa, J G

    1995-01-01

    Changes to the European standard series which have taken place since the last officially recommended alterations in 1988, are explained. New to the series is the sesquiterpene lactone mix. The PPD black rubber mix and the quinoline mix have been replaced by single components; one of the p-hydroxy......-hydroxybenzoates has been left out of the paraben mix. Ethylenediamine dihydrochloride has been dropped from the series....

  11. The European standard series. European Environmental and Contact Dermatitis Research Group (EECDRG)

    DEFF Research Database (Denmark)

    Bruynzeel, D P; Andersen, Klaus Ejner; Camarasa, J G

    1995-01-01

    Changes to the European standard series which have taken place since the last officially recommended alterations in 1988, are explained. New to the series is the sesquiterpene lactone mix. The PPD black rubber mix and the quinoline mix have been replaced by single components; one of the p-hydroxy......-hydroxybenzoates has been left out of the paraben mix. Ethylenediamine dihydrochloride has been dropped from the series....

  12. Quantum Unique Ergodicity for Eisenstein Series on the Hilbert Modular Group over a Totally Real Field

    DEFF Research Database (Denmark)

    Truelsen, Jimi Lee

    W. Luo and P. Sarnak have proved quantum unique ergodicity for Eisenstein series on $PSL(2,Z) \\backslash H$. We extend their result to Eisenstein series on $PSL(2,O) \\backslash H^n$, where $O$ is the ring of integers in a totally real field of degree $n$ over $Q$ with narrow class number one, using...... the Eisenstein series considered by I. Efrat. We also give an expository treatment of the theory of Hecke operators on non-holomorphic Hilbert modular forms....

  13. Analyzing Group Level Effects with Clustered Data Using Taylor Series Linearization

    Directory of Open Access Journals (Sweden)

    Francis L. Huang

    2014-11-01

    Full Text Available Clustered data (e.g., students within schools are often analyzed in educational research where data are naturally nested. As a consequence, multilevel modeling (MLM has commonly been used to study the contextual or group-level (e.g., school effects on individual outcomes. The current study investigates the use of an alternative procedure to MLM: regression using Taylor series linearization (TSL variance estimation. Despite the name, regressions using TSL are straightforward to conduct, can yield consistent and unbiased estimates and standard errors (given the appropriate conditions, and can be performed using a variety of commercially- and freely-available statistical software. I analyze a subsample of the High School and Beyond (HSB dataset using MLM, regression using TSL, and ordinary least squares regression and compare results. In addition, 12,000 random samples are drawn from the HSB dataset of varying level-one and level-two sample sizes in order to compute biases in standard errors based on the different conditions. Sample R and SAS syntax showing how to run regressions using TSL are provided

  14. Large intraspecific genetic variation within the Saffron-Crocus group (Crocus L., Series Crocus; Iridaceae)

    DEFF Research Database (Denmark)

    Larsen, Bjarne; Orabi, Jihad; Pedersen, Carsten

    2015-01-01

    Series Crocus comprises ten autumn-flowering species, including the cultivated Crocus sativus, Saffron-Crocus. Interspecific genetic variation was examined in all species of the series, except for C. naqabensis. Intraspecific genetic and morphological variation was considered in the three Greek...

  15. Quantum Unique Ergodicity for Eisenstein Series on the Hilbert Modular Group over a Totally Real Field

    DEFF Research Database (Denmark)

    Truelsen, Jimi Lee

    W. Luo and P. Sarnak have proved quantum unique ergodicity for Eisenstein series on $PSL(2,Z) \\backslash H$. We extend their result to Eisenstein series on $PSL(2,O) \\backslash H^n$, where $O$ is the ring of integers in a totally real field of degree $n$ over $Q$ with narrow class number one, usi...

  16. Quantum unique ergodicity of Eisenstein series on the Hilbert modular group over a totally real field

    DEFF Research Database (Denmark)

    Truelsen, Jimi Lee

    2011-01-01

    W. Luo and P. Sarnak have proved the quantum unique ergodicity property for Eisenstein series on PSL(2, )\\. Their result is quantitative in the sense that they find the precise asymptotics of the measure considered. We extend their result to Eisenstein series on , where is the ring of integers in...

  17. Perceived pros and cons of smoking and quitting in hard-core smokers: a focus group study.

    Science.gov (United States)

    Bommelé, Jeroen; Schoenmakers, Tim M; Kleinjan, Marloes; van Straaten, Barbara; Wits, Elske; Snelleman, Michelle; van de Mheen, Dike

    2014-02-18

    In the last decade, so-called hard-core smokers have received increasing interest in research literature. For smokers in general, the study of perceived costs and benefits (or 'pros and cons') of smoking and quitting is of particular importance in predicting motivation to quit and actual quitting attempts. Therefore, this study aims to gain insight into the perceived pros and cons of smoking and quitting in hard-core smokers. We conducted 11 focus group interviews among current hard-core smokers (n = 32) and former hard-core smokers (n = 31) in the Netherlands. Subsequently, each participant listed his or her main pros and cons in a questionnaire. We used a structural procedure to analyse the data obtained from the group interviews and from the questionnaires. Using the qualitative data of both the questionnaires and the transcripts, the perceived pros and cons of smoking and smoking cessation were grouped into 6 main categories: Finance, Health, Intrapersonal Processes, Social Environment, Physical Environment and Food and Weight. Although the perceived pros and cons of smoking in hard-core smokers largely mirror the perceived pros and cons of quitting, there are some major differences with respect to weight, social integration, health of children and stress reduction, that should be taken into account in clinical settings and when developing interventions. Based on these findings we propose the 'Distorted Mirror Hypothesis'.

  18. Coordination of opposing sex-specific and core muscle groups regulates male tail posture during Caenorhabditis elegans male mating behavior

    Directory of Open Access Journals (Sweden)

    Sternberg Paul W

    2009-06-01

    Full Text Available Abstract Background To survive and reproduce, animals must be able to modify their motor behavior in response to changes in the environment. We studied a complex behavior of Caenorhabditis elegans, male mating behavior, which provided a model for understanding motor behaviors at the genetic, molecular as well as circuit level. C. elegans male mating behavior consists of a series of six sub-steps: response to contact, backing, turning, vulva location, spicule insertion, and sperm transfer. The male tail contains most of the sensory structures required for mating, in addition to the copulatory structures, and thus to carry out the steps of mating behavior, the male must keep his tail in contact with the hermaphrodite. However, because the hermaphrodite does not play an active role in mating and continues moving, the male must modify his tail posture to maintain contact. We provide a better understanding of the molecular and neuro-muscular pathways that regulate male tail posture during mating. Results Genetic and laser ablation analysis, in conjunction with behavioral assays were used to determine neurotransmitters, receptors, neurons and muscles required for the regulation of male tail posture. We showed that proper male tail posture is maintained by the coordinated activity of opposing muscle groups that curl the tail ventrally and dorsally. Specifically, acetylcholine regulates both ventral and dorsal curling of the male tail, partially through anthelmintic levamisole-sensitive, nicotinic receptor subunits. Male-specific muscles are required for acetylcholine-driven ventral curling of the male tail but dorsal curling requires the dorsal body wall muscles shared by males and hermaphrodites. Gamma-aminobutyric acid activity is required for both dorsal and ventral acetylcholine-induced curling of the male tail and an inhibitory gamma-aminobutyric acid receptor, UNC-49, prevents over-curling of the male tail during mating, suggesting that cross

  19. The contribution of adenines in the catalytic core of 10-23 DNAzyme improved by the 6-amino group modifications.

    Science.gov (United States)

    Zhu, Junfei; Li, Zhiwen; Wang, Qi; Liu, Yang; He, Junlin

    2016-09-15

    In the catalytic core of 10-23 DNAzyme, its five adenine residues are moderate conservative, but with highly conserved functional groups like 6-amino group and 7-nitrogen atom. It is this critical conservation that these two groups could be modified for better contribution. With 2'-deoxyadenosine analogues, several functional groups were introduced at the 6-amino group of the five adenine residues. 3-Aminopropyl substituent at 6-amino group of A15 resulted in a five-fold increase of kobs. More efficient DNAzymes are expected by delicate design of the linkage and the external functional groups for this 6-amino group of A15. With this modification approach, other functional groups or residues could be optimized for 10-23 DNAzyme.

  20. Development of a Provisional Core Domain Set for Polymyalgia Rheumatica : Report from the OMERACT 12 Polymyalgia Rheumatica Working Group

    NARCIS (Netherlands)

    Helliwell, Toby; Brouwer, Elisabeth; Pease, Colin T.; Hughes, Rodney; Hill, Catherine L.; Neill, Lorna M.; Halls, Serena; Simon, Lee S.; Mallen, Christian D.; Boers, Maarten; Kirwan, John R.; Mackie, Sarah L.

    2016-01-01

    Objective. The Outcome Measures in Rheumatology (OMERACT) polymyalgia rheumatica (PMR) working group aims to develop a core set of outcome measures to be used in clinical trials for PMR. Previous reports from OMERACT 11 included a qualitative study of the patient experience and a preliminary literat

  1. Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition.

    Science.gov (United States)

    Wood, Michael R; Noetzel, Meredith J; Tarr, James C; Rodriguez, Alice L; Lamsal, Atin; Chang, Sichen; Foster, Jarrett J; Smith, Emery; Chase, Peter; Hodder, Peter S; Engers, Darren W; Niswender, Colleen M; Brandon, Nicholas J; Wood, Michael W; Duggan, Mark E; Conn, P Jeffrey; Bridges, Thomas M; Lindsley, Craig W

    2016-09-01

    This Letter describes the chemical optimization of a novel series of M4 PAMs based on a non-enolizable ketone core, identified from an MLPCN functional high-throughput screen. The HTS hit was potent, selective and CNS penetrant; however, the compound was highly cleared in vitro and in vivo. SAR provided analogs for which M4 PAM potency and CNS exposure were maintained; yet, clearance remained high. Metabolite identification studies demonstrated that this series was subject to rapid, and near quantitative, reductive metabolism to the corresponding secondary alcohol metabolite that was devoid of M4 PAM activity. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Dendritic host molecules with a polycationic core and an outer Shell of dodecyl groups

    NARCIS (Netherlands)

    van de Coevering, R.; Bruijnincx, P.C.A.; van Walree, C.A.; Klein Gebbink, R.J.M.; van Koten, G.

    2007-01-01

    The synthesis of a topologically new type of dendrimer is presented in which a permanently positively charged core is decorated with a shell that is apolar and aliphatic in nature. The novel polyionic dendrimers were successfully applied as hosts for a predefined number of anionic guests, as is show

  3. Switching of the core structures of glycosphingolipids from globo- and lacto- to ganglio-series upon human embryonic stem cell differentiation.

    Science.gov (United States)

    Liang, Yuh-Jin; Kuo, Huan-Hsien; Lin, Chi-Hung; Chen, Yen-Ying; Yang, Bei-Chia; Cheng, Yuan-Yuan; Yu, Alice L; Khoo, Kay-Hooi; Yu, John

    2010-12-28

    A systematic survey of expression profiles of glycosphingolipids (GSLs) in two hESC lines and their differentiated embryoid body (EB) outgrowth with three germ layers was carried out using immunofluorescence, flow cytometry, and MALDI-MS and MS/MS analyses. In addition to the well-known hESC-specific markers stage-specific embryonic antigen 3 (SSEA-3) and SSEA-4, we identified several globosides and lacto-series GSLs, previously unrevealed in hESCs, including Gb(4)Cer, Lc(4)Cer, fucosyl Lc(4)Cer, Globo H, and disialyl Gb(5)Cer. During hESC differentiation into EBs, MS analysis revealed a clear-cut switch in the core structures of GSLs from globo- and lacto- to ganglio-series, which was not as evident by immunostaining with antibodies against SSEA-3 and SSEA-4, owing to their cross-reactivities with various glycosphingolipids. Such a switch was attributable to altered expression of key glycosyltransferases (GTs) in the biosynthetic pathways by the up-regulation of ganglio-series-related GTs with simultaneous down-regulation of globo- and lacto-series-related GTs. Thus, these results provide insights into the unique stage-specific transition and mechanism for alterations of GSL core structures during hESC differentiation. In addition, unique glycan structures uncovered by MS analyses may serve as surface markers for further delineation of hESCs and help identify of their functional roles not only in hESCs but also in cancers.

  4. Power law classification scheme of time series correlations. On the example of G20 group

    Science.gov (United States)

    Miśkiewicz, Janusz

    2013-05-01

    A power law classification scheme (PLCS) of time series correlations is proposed. It is shown that PLCS provides the ability to classify nonlinear correlations and measure their stability. PLCS has been applied to gross domestic product (GDP) per capita of G20 members and their correlations analysed. It has been shown that the method does not only recognise linear correlations properly, but also allows to point out converging time series as well as to distinguish nonlinear correlations. PLCS is capable of crash recognition as it is shown in the Argentina example. Finally the strength of correlations and the stability of correlation matrices have been used to construct a minimum spanning tree (MST). The results were compared with those based on the ultrametric distance (UD). Comparing the structures of MST, UD and PLCS indicates that the latter one is more complicated, but better fits the expected economic relations within the G20.

  5. The bow shock, cold fronts and disintegrating cool core in the merging galaxy group RXJ0751.3+5012

    CERN Document Server

    Russell, H R; McNamara, B R; Edge, A C; Sanders, J S; Nulsen, P E J; Baum, S A; Donahue, M; O'Dea, C P

    2014-01-01

    We present a new Chandra X-ray observation of the off-axis galaxy group merger RXJ0751.3+5012. The hot atmospheres of the two colliding groups appear highly distorted by the merger. The images reveal arc-like cold fronts around each group core, produced by the motion through the ambient medium, and the first detection of a group merger shock front. We detect a clear density and temperature jump associated with a bow shock of Mach number M=1.9+/-0.4 ahead of the northern group. Using galaxy redshifts and the shock velocity of 1100+/-300 km/s, we estimate that the merger axis is only 10deg from the plane of the sky. From the projected group separation of 90 kpc, this corresponds to a time since closest approach of 0.1 Gyr. The northern group hosts a dense, cool core with a ram pressure stripped tail of gas extending 100 kpc. The sheared sides of this tail appear distorted and broadened by Kelvin-Helmholtz instabilities. We use the presence of this substructure to place an upper limit on the magnetic field stren...

  6. Persistent threats to validity in single-group interrupted time series analysis with a cross over design.

    Science.gov (United States)

    Linden, Ariel

    2017-04-01

    The basic single-group interrupted time series analysis (ITSA) design has been shown to be susceptible to the most common threat to validity-history-the possibility that some other event caused the observed effect in the time series. A single-group ITSA with a crossover design (in which the intervention is introduced and withdrawn 1 or more times) should be more robust. In this paper, we describe and empirically assess the susceptibility of this design to bias from history. Time series data from 2 natural experiments (the effect of multiple repeals and reinstatements of Louisiana's motorcycle helmet law on motorcycle fatalities and the association between the implementation and withdrawal of Gorbachev's antialcohol campaign with Russia's mortality crisis) are used to illustrate that history remains a threat to ITSA validity, even in a crossover design. Both empirical examples reveal that the single-group ITSA with a crossover design may be biased because of history. In the case of motorcycle fatalities, helmet laws appeared effective in reducing mortality (while repealing the law increased mortality), but when a control group was added, it was shown that this trend was similar in both groups. In the case of Gorbachev's antialcohol campaign, only when contrasting the results against those of a control group was the withdrawal of the campaign found to be the more likely culprit in explaining the Russian mortality crisis than the collapse of the Soviet Union. Even with a robust crossover design, single-group ITSA models remain susceptible to bias from history. Therefore, a comparable control group design should be included, whenever possible. © 2016 John Wiley & Sons, Ltd.

  7. Core Concepts of Human Rights and Inclusion of Vulnerable Groups in the Namibian Policy on Orthopaedic Technical Services

    Directory of Open Access Journals (Sweden)

    Malcolm MacLachlan

    2012-12-01

    Full Text Available Purpose: Despite a highly progressive legislation and clear governmental commitment, living conditions among persons with disabilities in Namibia are systematically lower than among persons without disabilities. This implies that persons with disabilities are denied equal opportunities to participate and contribute to society, and consequently are denied their human rights.Methods: EquiFrame, an innovative policy analysis framework, was used to analyse Namibian Policy on Orthopaedic Technical Services. EquiFrame evaluates the degree of stated commitment of an existing health policy to 21 Core Concepts of human rights and to 12 Vulnerable Groups, guided by the ethos of universal, equitable and accessible health services.Results: A number of Core Concepts of human rights and Vulnerable Groups were found to be absent in the Namibian Policy on Orthopaedic Technical Services, and its Overall Summary Ranking was assessed as Moderate.Conclusion and Implications: The Namibian health sector faces significant challenges in addressing inequities with respect to its policy on Orthopaedic Technical Services. If policy content, or policy ‘on the books’, is not inclusive of vulnerable groups and observant of core concepts of human rights, then health practices are also unlikely to do so. This paper illustrates that EquiFrame can provide the strategic guidance for the reform of Namibian Orthopaedic Technical Services policy, leading to universal and equitable access to healthcare.doi: 10.5463/dcid.v23i3.132

  8. Education of Minority Ethnic Groups in Scotland: A Review of Research. SCRE Research Report Series.

    Science.gov (United States)

    Powney, Janet; McPake, Joanna; Hall, Stuart; Lyall, Lindsay

    This review examines research done and information made available regarding the education of minority ethnic groups in Scotland. Compilers of the review used and commented on available statistical information and Scottish studies relevant to minority ethnic groups and their education at all levels. The intent of the review was to determine whether…

  9. Intensification of the Learning Process: Educational Grouping Questionnaire. A Series of Reports Designed for Classroom Use.

    Science.gov (United States)

    Bucks County Public Schools, Doylestown, PA.

    This report consists of a classification of elementary school age children and information concerning an Educational Grouping Questionnaire, which is designed to help the classroom teacher group her students. (See TM 001 368 for example of questionnaire; see TM 001 363 for summary of report; for other related documents, see TM 001 160, 364-366,…

  10. Synthesis of a series of maltotriose phosphates with an evaluation of the utility of a fluorous phosphate protecting group.

    Science.gov (United States)

    Liu, Lin; Pohl, Nicola L B

    2013-03-22

    A series of methyl maltotrioside phosphates were synthesized for application in the determination of the actual molecular substrate of the Lafora enzyme involved in Lafora disease. Several different synthetic routes were applied for the successful synthesis of six methyl maltotrioside phosphate regioisomers. The utility of a new fluorous phosphate protecting group was also evaluated, but its utility was found to be limited in this particular late stage introduction.

  11. Measuring Group Synchrony: A Cluster-Phase Method for Analyzing Multivariate Movement Time-Series

    Directory of Open Access Journals (Sweden)

    Michael eRichardson

    2012-10-01

    Full Text Available A new method for assessing group synchrony is introduced as being potentially useful for objectively determining degree of group cohesiveness or entitativity. The cluster-phase method of Frank and Richardson (2010 was used to analyze movement data from the rocking chair movements of six-member groups who rocked their chairs while seated in a circle facing the center. In some trials group members had no information about others’ movements (their eyes were shut or they had their eyes open and gazed at a marker in the center of the group. As predicted, the group level synchrony measure was able to distinguish between situations where synchrony would have been possible and situations where it would be impossible. Moreover, other aspects of the analysis illustrated how the cluster phase measures can be used to determine the type of patterning of group synchrony, and, when integrated with multi-level modeling, can be used to examine individual-level differences in synchrony and dyadic level synchrony as well.

  12. Convergence in Lp-norm of Fourier Series on the Complete Product of Quaternion Groups with Bounded Orders

    Institute of Scientific and Technical Information of China (English)

    Gyorgy GAT; Rodolfo TOLEDO

    2014-01-01

    A well-known result for Vilenkin systems is the fact that for all 1 < p < ∞ the n-th partial sums of Fourier series of all functions in the space Lp converge to the function in Lp-norm. This statement can not be generalized to any representative product system on the complete product of finite non-abelian groups, but even then it is true for the complete product of quaternion groups with bounded orders and monomial representative product system ordered in a specific way.

  13. New core-substituted with electron-donating group 1,8-naphthalimides towards optoelectronic applications

    Energy Technology Data Exchange (ETDEWEB)

    Schab-Balcerzak, Ewa, E-mail: eschab-balcerzak@cmpw-pan.edu.pl [Centre of Polymer and Carbon Materials, Polish Academy of Sciences, 34 M. Curie-Sklodowska Street, 41-819 Zabrze (Poland); Institute of Chemistry, University of Silesian, 9 Szkolna Street, 40-006 Katowice (Poland); Siwy, Mariola [Centre of Polymer and Carbon Materials, Polish Academy of Sciences, 34 M. Curie-Sklodowska Street, 41-819 Zabrze (Poland); Filapek, Michal; Kula, Slawomir; Malecki, Grzegorz [Institute of Chemistry, University of Silesian, 9 Szkolna Street, 40-006 Katowice (Poland); Laba, Katarzyna; Lapkowski, Mieczyslaw [Centre of Polymer and Carbon Materials, Polish Academy of Sciences, 34 M. Curie-Sklodowska Street, 41-819 Zabrze (Poland); Faculty of Chemistry, Silesian University of Technology, 9 Strzody Steet, 44-100 Gliwice (Poland); Janeczek, Henryk; Domanski, Marian [Centre of Polymer and Carbon Materials, Polish Academy of Sciences, 34 M. Curie-Sklodowska Street, 41-819 Zabrze (Poland)

    2015-10-15

    New 1,8-naphthalimides with thiophene or bithiophene structure attached by an imine linkage to naphthalene core were synthesized. The structures of obtained compounds were characterized by FTIR, {sup 1}H NMR spectroscopy, elemental analysis and for elected compounds by HRMS (ESI) spectrometry. Thermal, optical and electrochemical properties of obtained 1,8-naphthalimides were investigated. Most of them exhibited glass-forming properties with glass transition temperatures in the range of 73–278 °C. Optical properties of the prepared compounds were examined by UV–vis and photoluminescence (PL) measurements. They emitted light in chloroform solution with emission maximum at ca. 500 nm with the highest quantum yield of fluorescence around 0.46 and green one in NMP solution. In blend with PMMA blue emission was observed with the highest quantum yield of fluorescence around 0.24. All compounds are electrochemically active, and undergo reversible reduction and irreversible or quasi-reversible oxidation process as was found in cyclic and differential pulse voltammetry (CV and DPV) studies. They showed electrochemical band gaps in the range 2.28–2.68 eV. Additionally, the electronic properties, that is, orbital energies and resulting energy gap were calculated by density functional theory (DFT). Additionally, selected compounds were preliminary tested as electroluminescence materials in devices with structure ITO/PVK:NI blend/Al. - Highlights: • We obtained new core substituted 1,8-naphthalimides. • They emitted light in CHCl{sub 3} with the largest PL quantum yield measure for these compounds of 0.46. • They emitted blue light in a blend with PMMA with the largest Φ{sub f} 0.24 measured for these compounds. • Their electrochemical energy band gap was in the range of 2.28–2.68 eV. • Preliminary investigations showed that green electroluminescence was observed.

  14. A new series of two-ring-based side chain liquid crystalline polymers: synthesis and mesophase characterization

    CSIR Research Space (South Africa)

    Reddy, GSM

    2013-05-01

    Full Text Available A new series of side chain liquid crystalline polymers containing a core, a butamethylenoxy spacer, ester groups, and terminal alkoxy groups were synthesised and their structures were confirmed. The core was constructed with two phenyl rings...

  15. Core-firm Based View on the Mechanism of Constructing a Corporate Innovation Ecosystem: A Case Study of Haier Group

    DEFF Research Database (Denmark)

    Jiang, Shimei; Wang, Ziyuan; Hu, Yimei

    2016-01-01

    The fierce transformation of the competitive status of business world in the 21st century has urged the innovation activities turned from mechanistic and deterministic to ecological and organic. The study firstly defines the concept of core firm based on reviewing existing corporate innovation...... ecosystem literature, and then adopts a multi-embedded case study method on Haier Group’s corporate innovation ecosystem, focusing on six exploratory sub-cases. Based on qualitative coding and analysis on the value realization of six new product/technology of the Haier Group, we investigate how a core firm...... constructing a corporate innovation ecosystem through building up an innovation platform that include multi-level collaborative relationships based on different technologies; while at the same time integrating non-technological issues such as strategy, culture, management, organization, institution and market...

  16. Duality for Ext-groups and extensions of discrete series for graded Hecke algebras

    NARCIS (Netherlands)

    Chan, K.Y.

    2016-01-01

    In this paper, we study extensions of graded affine Hecke algebra modules. In particular, based on an explicit projective resolution on graded affine Hecke algebra modules, we prove a duality result for Ext-groups. This duality result with an Ind-Res resolution gives an algebraic proof of the fact t

  17. Report of the Expert Group Meeting on Population Projections. Asian Population Studies Series No. 33.

    Science.gov (United States)

    United Nations Economic and Social Commission for Asia and the Pacific, Bangkok (Thailand).

    A group of experts on population projections was convened in Thailand in late 1975. It was organized by the United Nations Economic and Social Commission for Asia and the Pacific. This report is the result of background papers used at the conference, reactions to the papers, and further writing. Chapter headings are: (1) Introduction; (2) The Role…

  18. Theories of behaviour change synthesised into a set of theoretical groupings: introducing a thematic series on the theoretical domains framework.

    Science.gov (United States)

    Francis, Jill J; O'Connor, Denise; Curran, Janet

    2012-04-24

    Behaviour change is key to increasing the uptake of evidence into healthcare practice. Designing behaviour-change interventions first requires problem analysis, ideally informed by theory. Yet the large number of partly overlapping theories of behaviour makes it difficult to select the most appropriate theory. The need for an overarching theoretical framework of behaviour change was addressed in research in which 128 explanatory constructs from 33 theories of behaviour were identified and grouped. The resulting Theoretical Domains Framework (TDF) appears to be a helpful basis for investigating implementation problems. Research groups in several countries have conducted TDF-based studies. It seems timely to bring together the experience of these teams in a thematic series to demonstrate further applications and to report key developments. This overview article describes the TDF, provides a brief critique of the framework, and introduces this thematic series.In a brief review to assess the extent of TDF-based research, we identified 133 papers that cite the framework. Of these, 17 used the TDF as the basis for empirical studies to explore health professionals' behaviour. The identified papers provide evidence of the impact of the TDF on implementation research. Two major strengths of the framework are its theoretical coverage and its capacity to elicit beliefs that could signify key mediators of behaviour change. The TDF provides a useful conceptual basis for assessing implementation problems, designing interventions to enhance healthcare practice, and understanding behaviour-change processes. We discuss limitations and research challenges and introduce papers in this series.

  19. Lead optimization of the VU0486321 series of mGlu1 PAMs. Part 1: SAR of modifications to the central aryl core.

    Science.gov (United States)

    Garcia-Barrantes, Pedro M; Cho, Hyekyung P; Blobaum, Anna L; Niswender, Colleen M; Conn, P Jeffrey; Lindsley, Craig W

    2015-11-15

    This Letter describes the lead optimization of the VU0486321 series of mGlu1 positive allosteric modulators (PAMs). While first generation PAMs from Roche were reported in the late 1990s, little effort has focused on the development of mGlu1 PAMs since. New genetic data linking loss-of-function mutant mGlu1 receptors to schizophrenia, bipolar disorder and other neuropsychiatric disorders has rekindled interest in the target, but the ideal in vivo probe, for example, with good PK, brain penetration and low plasma protein binding, for robust target validation has been lacking. Here we describe the first modifications to the central aryl core of the VU0486321 series, where robust SAR was noted. Moreover, structural variants were identified that imparted selectivity (up to >793-fold) versus mGlu4.

  20. Photoluminescence effects of graphitic core size and surface functional groups in carbon dots: COO− induced red-shift emission

    KAUST Repository

    Hola, Katerina

    2014-04-01

    We present a simple molecular approach to control the lipophilic/ hydrophilic nature of photoluminescent carbon dots (CDs) based on pyrolysis of alkyl gallate precursors. Depending on the gallic acid derivative used, CDs with different alkyl groups (methyl, propyl, lauryl) on the surface can be obtained by isothermal heating at 270 C. This precursor-derived approach allows not only the control of lipophilicity but also the length of the particular alkyl chain enables the control over both the size and photoluminescence (PL) of the prepared CDs. Moreover, the alkyl chains on the CDs surface can be readily converted to carboxylate groups via a mild base hydrolysis to obtain water dispersible CDs with a record biocompatibility. The observed differences in PL properties of CDs and time-resolved PL data, including contributions from carbogenic cores and surface functional group, are rationalized and discussed in detail using time-dependent density functional theory (TD-DFT) calculations. © 2013 Elsevier Ltd. All rights reserved.

  1. Allied Geographical Section, Southwest Pacific Area, Terrain Handbook 57. Jolo Group (Philippine Series)

    Science.gov (United States)

    1945-02-12

    A political subdivision of a municipality. Baguio: Typhoon. Bodega: Warehouse. Banca : Canoe made by hollowing out a log. Batil: Small sailing...2 COASTAL INFORMATION A—OFFSHORE CONDITIONS 1. GENERAL: Jolo is one of largest and most centrally situated islands in Sulu Archipelago...has houses grouped tightly along Maimbung R which is main transportation avenue. h. Roads: Route 1 (Jolo to Liangliang) runs through central

  2. Report from the kick-off meeting of the Cochrane Skin Group Core Outcome Set Initiative (CSG-COUSIN).

    Science.gov (United States)

    Schmitt, J; Deckert, S; Alam, M; Apfelbacher, C; Barbaric, J; Bauer, A; Chalmers, J; Chosidow, O; Delamere, F; Doney, E; Eleftheriadou, V; Grainge, M; Johannsen, L; Kottner, J; Le Cleach, L; Mayer, A; Pinart, M; Prescott, L; Prinsen, C A C; Ratib, S; Schlager, J G; Sharma, M; Thomas, K S; Weberschock, T; Weller, K; Werner, R N; Wild, T; Wilkes, S R; Williams, H C

    2016-02-01

    A major obstacle of evidence-based clinical decision making is the use of nonstandardized, partly untested outcome measurement instruments. Core Outcome Sets (COSs) are currently developed in different medical fields to standardize and improve the selection of outcomes and outcome measurement instruments in clinical trials, in order to pool results of trials or to allow indirect comparison between interventions. A COS is an agreed minimum set of outcomes that should be measured and reported in all clinical trials of a specific disease or trial population. The international, multidisciplinary Cochrane Skin Group Core Outcome Set Initiative (CSG-COUSIN) aims to develop and implement COSs in dermatology, thus making trial evidence comparable and, herewith, more useful for clinical decision making. The inaugural meeting of CSG-COUSIN was held on 17-18 March 2015 in Dresden, Germany, as the exclusive theme of the Annual Cochrane Skin Group Meeting. In total, 29 individuals representing a broad mix of different stakeholder groups, professions, skills and perspectives attended. This report provides a description of existing COS initiatives in dermatology, highlights current methodological challenges in COS development, and presents the concept, aims and structure of CSG-COUSIN.

  3. Time series analysis applied to construct US natural gas price functions for groups of states

    Energy Technology Data Exchange (ETDEWEB)

    Kalashnikov, V.V. [Departamento de Ingenieria Industrial y de Sistemas, Tecnologico de Monterrey, Av. Eugenio Garza Sada 2501 Sur, Col. Tecnologico, Monterrey, Nuevo Leon, 64849 (Mexico); Matis, T.I. [Deparment of Industrial Engineering, Texas Tech University, 2500 Broadway, Lubbock, TX 79409 (United States); Perez-Valdes, G.A. [Departamento de Ingenieria Industrial y de Sistemas, Tecnologico de Monterrey, Av. Eugenio Garza Sada 2501 Sur, Col. Tecnologico, Monterrey, Nuevo Leon, 64849 (Mexico); Deparment of Industrial Engineering, Texas Tech University, 2500 Broadway, Lubbock, TX 79409 (United States)

    2010-07-15

    The study of natural gas markets took a considerably new direction after the liberalization of the natural gas markets during the early 1990s. As a result, several problems and research opportunities arose for those studying the natural gas supply chain, particularly the marketing operations. Consequently, various studies have been undertaken about the econometrics of natural gas. Several models have been developed and used for different purposes, from descriptive analysis to practical applications such as price and consumption forecasting. In this work, we address the problem of finding a pooled regression formula relating the monthly figures of price and consumption volumes for each state of the United States during the last twenty years. The model thus obtained is used as the basis for the development of two methods aimed at classifying the states into groups sharing a similar price/consumption relationship: a dendrogram application, and an heuristic algorithm. The details and further applications of these grouping techniques are discussed, along with the ultimate purpose of using this pooled regression model to validate data employed in the stochastic optimization problem studied by the authors. (author)

  4. Patient-perceived value of Medication Therapy Management (MTM services: a series of focus groups

    Directory of Open Access Journals (Sweden)

    Amanda Brummel, PharmD

    2012-01-01

    Full Text Available Objective: To determine the patient-perceived value of MTM services and non-financial barriers preventing patients with insurance coverage from receiving MTM services. Design: Focus groups. Setting: Fairview Pharmacy Services, Minneapolis, MN.Participants: Three focus groups, each with five to nine participants, consisting of different participant populations: (i patients who paid out-of-pocket to receive MTM services; (ii insurance beneficiaries, under which MTM is a covered benefit and participants may have received incentives for receiving MTM services; (iii patients with an insurance plan which covers MTM services who were recruited to receive MTM services but declined. Intervention: MTM services. Main Outcome Measure: Patient-perceived value of MTM services and non-financial barriers. Results: Seven themes were identified relating to the patient-perceived value of MTM services: collaboration of the health care team, MTM pharmacist as a supporter/advocate/confidant, MTM pharmacist as a resource for questions and education, accessibility to the MTM pharmacist, financial incentives for participation in MTM services, MTM pharmacy as a specialty field, and the MTM pharmacist as a coordinator. Three themes were identified regarding patient-perceived non-financial barriers to receiving MTM services, including: availability of the MTM pharmacist, patient/physician lack of knowledge of MTM services, patient’s belief that MTM services are not needed. Conclusion: MTM is a service which patients identify as valuable. Patients are able to identify non-financial barriers that may prevent some patients from receiving MTM services. This study provides preliminary evidence of both the value and barriers perceived by patients.

  5. Switching of the core structures of glycosphingolipids from globo- and lacto- to ganglio-series upon human embryonic stem cell differentiation

    Science.gov (United States)

    Liang, Yuh-Jin; Kuo, Huan-Hsien; Chen, Yen-Ying; Yang, Bei-Chia; Cheng, Yuan-Yuan; Yu, Alice L.; Khoo, Kay-Hooi; Yu, John

    2010-01-01

    A systematic survey of expression profiles of glycosphingolipids (GSLs) in two hESC lines and their differentiated embryoid body (EB) outgrowth with three germ layers was carried out using immunofluorescence, flow cytometry, and MALDI-MS and MS/MS analyses. In addition to the well-known hESC-specific markers stage-specific embryonic antigen 3 (SSEA-3) and SSEA-4, we identified several globosides and lacto-series GSLs, previously unrevealed in hESCs, including Gb4Cer, Lc4Cer, fucosyl Lc4Cer, Globo H, and disialyl Gb5Cer. During hESC differentiation into EBs, MS analysis revealed a clear-cut switch in the core structures of GSLs from globo- and lacto- to ganglio-series, which was not as evident by immunostaining with antibodies against SSEA-3 and SSEA-4, owing to their cross-reactivities with various glycosphingolipids. Such a switch was attributable to altered expression of key glycosyltransferases (GTs) in the biosynthetic pathways by the up-regulation of ganglio-series–related GTs with simultaneous down-regulation of globo- and lacto-series–related GTs. Thus, these results provide insights into the unique stage-specific transition and mechanism for alterations of GSL core structures during hESC differentiation. In addition, unique glycan structures uncovered by MS analyses may serve as surface markers for further delineation of hESCs and help identify of their functional roles not only in hESCs but also in cancers. PMID:21149694

  6. Anisotropies in the Neutrino Fluxes and Heating Profiles in Two-dimensional, Time-dependent, Multi-group Radiation Hydrodynamics Simulations of Rotating Core-Collapse Supernovae

    CERN Document Server

    Walder, R; Ott, C D; Livne, E; Jarrah, M

    2004-01-01

    Using the 2D multi-group, flux-limited diffusion version of the code VULCAN/2D, that also incorporates rotation, we have calculated the collapse, bounce, shock formation, and early post-bounce evolutionary phases of a core-collapse supernova for a variety of initial rotation rates. This is the first series of such multi-group calculations undertaken in supernova theory with fully multi-D tools. We find that though rotation generates pole-to-equator angular anisotropies in the neutrino radiation fields, the magnitude of the asymmetries is not as large as previously estimated. Moreover, we find that the radiation field is always more spherically symmetric than the matter distribution, with its plumes and convective eddies. We present the dependence of the angular anisotropy of the neutrino fields on neutrino species, neutrino energy, and initial rotation rate. Only for our most rapidly rotating model do we start to see qualitatively different hydrodynamics, but for the lower rates consistent with the pre-collap...

  7. 2D Multi-Angle, Multi-Group Neutrino Radiation-Hydrodynamic Simulations of Postbounce Supernova Cores

    CERN Document Server

    Ott, Christian D; Dessart, Luc; Livne, Eli

    2008-01-01

    We perform axisymmetric (2D) multi-angle, multi-group neutrino radiation-hydrodynamics calculations of the postbounce phase of core-collapse supernovae using a genuinely 2D discrete-ordinate (S_n) method. We follow the long-term postbounce evolution of the cores of one nonrotating and one rapidly-rotating 20-solar-mass stellar model for ~400 milliseconds from 160 ms to ~550 ms after bounce. We present a multi-D analysis of the multi-angle neutrino radiation fields and compare in detail with counterpart simulations carried out in the 2D multi-group flux-limited diffusion (MGFLD) approximation to neutrino transport. We find that 2D multi-angle transport is superior in capturing the global and local radiation-field variations associated with rotation-induced and SASI-induced aspherical hydrodynamic configurations. In the rotating model, multi-angle transport predicts much larger asymptotic neutrino flux asymmetries with pole to equator ratios of up to ~2.5, while MGFLD tends to sphericize the radiation fields al...

  8. Vibrational spectra study of fluorescent dendrimers built from the cyclotriphosphazene core with terminal dansyl and carbamate groups

    Science.gov (United States)

    Furer, V. L.; Vandyukova, I. I.; Vandyukov, A. E.; Fuchs, S.; Majoral, J. P.; Caminade, A. M.; Kovalenko, V. I.

    2011-08-01

    The FTIR and FT Raman spectra of the "Janus"-type dendrimers, possessing five carbamate groups on one side and five fluorescent dansyl derivatives on the other side, with amide G1 and hydrazone G2 central linkages were studied. These surface-block dendrimers are obtained by the coupling of two different dendrons. The FTIR and FT-Raman spectra of the zero generation dendrons, built from the hexafunctional cyclotriphosphazene core, with five dansyl terminal groups and one carbamate G0 v and one oxybenzaldehyde function G0v have been recorded. The structural optimization and normal mode analysis were performed for dendron G0v on the basis of the density functional theory (DFT). The calculated geometrical parameters and harmonic vibrational frequencies are predicted in a good agreement with the experimental data. It was found that dendron molecule G0v has a concave lens structure with planar -O-C6H4-CHdbnd O fragments and slightly non-planar cyclotriphosphazene core. The experimental IR and Raman spectra of dendron G0v were interpreted by means of potential energy distributions. Relying on DFT calculations a complete vibrational assignment is proposed. The strong band 1597 cm -1 show marked changes of the optical density in dependence of substituents in the aromatic ring. The frequencies of ν(N-H) bands in the IR spectra reveal the presence of the different types of H-bonds in the dendrimers.

  9. Core group approach to identify college students at risk for sexually transmitted infections "Core group" para identificar universitários em risco para infecções sexualmente transmissíveis

    Directory of Open Access Journals (Sweden)

    Miguel A Sánchez-Alemán

    2008-06-01

    Full Text Available OBJECTIVE: To analyze the core group for sexually transmitted infections (STI among college students. METHODS: Cross-sectional study carried out in a convenience sample comprising 711 college students of the public university of Morelos, Mexico, between 2001 and 2003. Sociodemographic and sexual behavior information were collected using self-applied questionnaires. Herpes simplex 2 (HSV-2 infection was tested in the blood. The number of sexual partners in the last year and cocaine consumption were used as indicators to construct the dependent variable "level of STI risk" in three categories: low, medium and high risk (core group. A multinomial analysis was conducted to evaluate whether different sex behaviors were associated with the variable "level of STI risk". RESULTS: There was significant association between HSV-2 seroprevalence and the variable "level of STI risk": 13%, 5.6% and 3.8% were found in high (core group, medium and low categories, respectively. There were gender differences regarding the core group. Men started having sexual intercourse earlier, had more sex partners, higher alcohol and drug consumption, higher frequency of sex intercourse with sex workers, exchanging sex for money, occasional and concurrent partners compared to women. CONCLUSIONS: The study findings suggest existing contextual characteristics in the study population that affect their sex behavior. In Mexico, the cultural conception of sexuality is determined mainly by gender differences where men engage in higher risky sexual behavior than women.OBJETIVO: Identificar al grupo core de infecciones de transmisión sexual (ITS en una población de estudiantes universitarios mexicanos. MÉTODOS: Se realizó un estudio transversal en una muestra por conveniencia que incluyó 711 estudiantes de una universidad pública de Morelos, México, entre 2001 y 2003. Las características sociodemográficas y de comportamiento sexual se obtuvieron mediante un cuestionario auto

  10. Group cognitive behaviour therapy for adults with Asperger syndrome and anxiety or mood disorder: a case series.

    Science.gov (United States)

    Weiss, Jonathan A; Lunsky, Yona

    2010-01-01

    Individuals with Asperger syndrome are at increased risk for mental health problems compared with the general population, especially with regard to mood and anxiety disorders. Generic mental health services are often ill-equipped to offer psychotherapeutic treatments to this population, and specialized supports are difficult to find. This case series used a manualized cognitive behaviour therapy group programme (Mind Over Mood) with three adults diagnosed with Asperger syndrome, who were each unable to access psychotherapy through mainstream mental health services. This review highlights the benefits of a cognitive behaviour therapy (CBT) group approach for adults with Asperger syndrome and suggests some potential modifications to traditional CBT provision.  © 2010 John Wiley & Sons, Ltd.

  11. A Predictive HQSAR Model for a Series of Tricycle Core Containing MMP-12 Inhibitors with Dibenzofuran Ring

    Directory of Open Access Journals (Sweden)

    Jamal Shamsara

    2014-01-01

    Full Text Available MMP-12 is a member of matrix metalloproteinases (MMPs family involved in pathogenesis of some inflammatory based diseases. Design of selective matrix MMPs inhibitors is still challenging because of binding pocket similarities among MMPs family. We tried to generate a HQSAR (hologram quantitative structure activity relationship model for a series of MMP-12 inhibitors. Compounds in the series of inhibitors with reported biological activity against MMP-12 were used to construct a predictive HQSAR model for their inhibitory activity against MMP-12. The HQSAR model had statistically excellent properties and possessed good predictive ability for test set compounds. The HQSAR model was obtained for the 26 training set compounds showing cross-validated q2 value of 0.697 and conventional r2 value of 0.986. The model was then externally validated using a test set of 9 compounds and the predicted values were in good agreement with the experimental results (rpred2=0.8733. Then, the external validity of the model was confirmed by Golbraikh-Tropsha and rm2 metrics. The color code analysis based on the obtained HQSAR model provided useful insights into the structural features of the training set for their bioactivity against MMP-12 and was useful for the design of some new not yet synthesized MMP-12 inhibitors.

  12. A 17-billion-solar-mass black hole in a group galaxy with a diffuse core

    CERN Document Server

    Thomas, Jens; McConnell, Nicholas J; Greene, Jenny E; Blakeslee, John P; Janish, Ryan

    2016-01-01

    Quasars are associated with and powered by the accretion of material onto massive black holes; the detection of highly luminous quasars with redshifts greater than z = 6 suggests that black holes of up to ten billion solar masses already existed 13 billion years ago. Two possible present-day dormant descendants of this population of active black holes have been found in the galaxies NGC 3842 and NGC 4889 at the centres of the Leo and Coma galaxy clusters, which together form the central region of the Great Wall - the largest local structure of galaxies. The most luminous quasars, however, are not confined to such high-density regions of the early Universe; yet dormant black holes of this high mass have not yet been found outside of modern-day rich clusters. Here we report observations of the stellar velocity distribution in the galaxy NGC 1600 - a relatively isolated elliptical galaxy near the centre of a galaxy group at a distance of 64 Mpc from Earth. We use orbit superposition models to determine that the ...

  13. Human embryonic stem cell-derived hematopoietic cells maintain core epigenetic machinery of the polycomb group/Trithorax Group complexes distinctly from functional adult hematopoietic stem cells.

    Science.gov (United States)

    Schnerch, Angelique; Lee, Jung Bok; Graham, Monica; Guezguez, Borhane; Bhatia, Mickie

    2013-01-01

    Hematopoietic cells derived from human embryonic stem cells (hESCs) have a number of potential utilities, including the modeling of hematological disorders in vitro, whereas the use for cell replacement therapies has proved to be a loftier goal. This is due to the failure of differentiated hematopoietic cells, derived from human pluripotent stem cells (hPSCs), to functionally recapitulate the in vivo properties of bona fide adult hematopoietic stem/progenitor cells (HSPCs). To better understand the limitations of differentiation programming at the molecular level, we have utilized differential gene expression analysis of highly purified cells that are enriched for hematopoietic repopulating activity across embryonic, fetal, and adult human samples, including in vivo explants of human HSPCs 8-weeks post-transplantation. We reveal that hESC-derived hematopoietic progenitor cells (eHPCs) fail to express critical transcription factors which are known to govern self-renewal and myeloid/lymphoid development and instead retain the expression of Polycomb Group (PcG) and Trithorax Group (TrxG) factors which are more prevalent in embryonic cell types that include EZH1 and ASH1L, respectively. These molecular profiles indicate that the differential expression of the core epigenetic machinery comprising PcGs/TrxGs in eHPCs may serve as previously unexplored molecular targets that direct hematopoietic differentiation of PSCs toward functional HSPCs in humans.

  14. Group IVA irons: New constraints on the crystallization and cooling history of an asteroidal core with a complex history

    Science.gov (United States)

    McCoy, T. J.; Walker, R. J.; Goldstein, J. I.; Yang, J.; McDonough, W. F.; Rumble, D.; Chabot, N. L.; Ash, R. D.; Corrigan, C. M.; Michael, J. R.; Kotula, P. G.

    2011-11-01

    We report analyses of 14 group IVA iron meteorites, and the ungrouped but possibly related, Elephant Moraine (EET) 83230, for siderophile elements by laser ablation ICP-MS and isotope dilution. EET was also analyzed for oxygen isotopic composition and metallographic structure, and Fuzzy Creek, currently the IVA with the highest Ni concentration, was analyzed for metallographic structure. Highly siderophile elements (HSE) Re, Os and Ir concentrations vary by nearly three orders of magnitude over the entire range of IVA irons, while Ru, Pt and Pd vary by less than factors of five. Chondrite normalized abundances of HSE form nested patterns consistent with progressive crystal-liquid fractionation. Attempts to collectively model the HSE abundances resulting from fractional crystallization achieved best results for 3 wt.% S, compared to 0.5 or 9 wt.% S. Consistent with prior studies, concentrations of HSE and other refractory siderophile elements estimated for the bulk IVA core and its parent body are in generally chondritic proportions. Projected abundances of Pd and Au, relative to more refractory HSE, are slightly elevated and modestly differ from L/LL chondrites, which some have linked with group IVA, based on oxygen isotope similarities. Abundance trends for the moderately volatile and siderophile element Ga cannot be adequately modeled for any S concentration, the cause of which remains enigmatic. Further, concentrations of some moderately volatile and siderophile elements indicate marked, progressive depletions in the IVA system. However, if the IVA core began crystallization with ˜3 wt.% S, depletions of more volatile elements cannot be explained as a result of prior volatilization/condensation processes. The initial IVA core had an approximately chondritic Ni/Co ratio, but a fractionated Fe/Ni ratio of ˜10, indicates an Fe-depleted core. This composition is most easily accounted for by assuming that the surrounding silicate shell was enriched in iron

  15. The global stratotype section and point (GSSP) for the base of the holocene series/epoch (Quaternary System/Period) in the NGRIP ice core

    DEFF Research Database (Denmark)

    Walker, Mike; Johnsen, Sigfus Johann; Rasmussen, Sune Olander;

    2008-01-01

    The Greenland ice core from NorthGRIP (NGRIP) contains a proxy climate record across the Pleistocene–Holocene boundary of unprecedented clarity and resolution. Analysis of an array of physical and chemical parameters within the ice enables the base of the Holocene, as reflected in the first signs...... of climatic warming at the end of the Younger Dryas/Greenland Stadial 1 cold phase, to be located with a high degree of precision. This climatic event is most clearly reflected in an abrupt shift in deuterium excess values, accompanied by more gradual changes in d18O, dust concentration, a range of chemical...... the Global Stratotype Section and Point (GSSP) for the base of the Holocene Series/Epoch (Quaternary System/Period)....

  16. Optimal Renormalization-Group Improvement of the Perturbative Series for the $e^+e^-$-Annihilation Cross-Section

    CERN Document Server

    Ahmady, M R; Elias, V; Fariborz, A H; McKeon, D G C; Sherry, T N; Squires, A; Steele, T G

    2003-01-01

    Using renormalization-group methods, we derive differential equations for the all-orders summation of logarithmic corrections to the QCD series for $R(s) =\\sigma(e^+e^- \\to {\\rm hadrons})/\\sigma(e^+e^- \\to \\mu^+\\mu^-)$, as obtained from the imaginary part of the purely-perturbative vector-current correlation function. We present explicit solutions for the summation of leading and up to three subsequent subleading orders of logarithms. The summations accessible from the four-loop vector-correlator not only lead to a substantial reduction in sensitivity to the renormalization scale, but necessarily impose a common infrared bound on perturbative approximations to $R(s)$, regardless of the infrared behaviour of the true QCD couplant.

  17. The first three coefficients in the high temperature series expansion of free energy for simple potential models with hard-sphere cores and continuous tails.

    Science.gov (United States)

    Zhou, Shiqi; Solana, J R

    2013-08-08

    The first three coefficients of the high temperature series expansion (HTSE) of the Helmholtz free energy for a number of simple potential models with hard-sphere cores plus continuous tails are obtained for the first time from Monte Carlo simulations. The potential models considered include Square-well, Sutherland, attractive Yukawa, and triangle-well with different potential ranges, as well as a model potential qualitatively resembling the depletion potential in colloidal dispersions. The simulation data are used to evaluate performance of a recent coupling parameter series expansion (CPSE) in calculating for these coefficients, and a traditional macroscopic compressibility approximation (MCA) for the second-order coefficient only. A comprehensive comparison based on these coefficients from the two theoretical approaches and simulations enables one to conclude that (i) unlike one common experience that the widely used MCA usually underestimates the second-order coefficient, the MCA can both overestimate and underestimate the second-order coefficient, and worsens as the range of the potential decreases; and (ii) in contrast, the CPSE not only reproduce the trends in the density dependence of the perturbation coefficients, even the third one, observed in the simulations, but also the agreement is quantitative in most cases, and this clearly highlights the potential of the CPSE in providing accurate estimations for the higher-order coefficients, thus giving rise to an accurate higher-order HTSE.

  18. The Effect of Environment on the Formation of Halpha Filaments and Cool Cores in Galaxy Groups and Clusters

    CERN Document Server

    McDonald, Michael; Mushotzky, Richard

    2011-01-01

    We present the results of a combined X-ray and Halpha study of 10 galaxy groups and 17 galaxy clusters using the Chandra X-ray Observatory and the Maryland Magellan Tunable Filter. We find no difference in the morphology or detection frequency of Halpha filaments in groups versus clusters, over the mass range 10^13 < M_500 < 10^15 Msun. The detection frequency of Halpha emission is shown to be only weakly dependent on the total mass of the system, at the 52% confidence level. In contrast, we find that the presence of Halpha filaments is strongly correlated with both the global (89% confidence level) and core (84%) ICM entropy, as well as the X-ray cooling rate (72%). The Halpha filaments are therefore an excellent proxy for the cooling ICM. The Halpha filaments are more strongly correlated with the cooling properties of the ICM than with the radio properties of the BCG; this further supports the scenario where these filaments are directly associated with a thermally-unstable, rapidly cooling ICM, rather...

  19. Petrographic maturity parameters of a Devonian shale maturation series, Appalachian Basin, USA. ICCP Thermal Indices Working Group interlaboratory exercise

    Science.gov (United States)

    Araujo, Carla Viviane; Borrego, Angeles G.; Cardott, Brian; das Chagas, Renata Brenand A.; Flores, Deolinda; Goncalves, Paula; Hackley, Paul C.; Hower, James C.; Kern, Marcio Luciano; Kus, Jolanta; Mastalerz, Maria; Filho, João Graciano Mendonça; de Oliveira Mendonça, Joalice; Rego Menezes, Taissa; Newman, Jane; Suarez-Ruiz, Isabel; Sobrinho da Silva, Frederico; Viegas de Souza, Igor

    2014-01-01

    This paper presents results of an interlaboratory exercise on organic matter optical maturity parameters using a natural maturation series comprised by three Devonian shale samples (Huron Member, Ohio Shale) from the Appalachian Basin, USA. This work was conducted by the Thermal Indices Working Group of the International Committee for Coal and Organic Petrology (ICCP) Commission II (Geological Applications of Organic Petrology). This study aimed to compare: 1. maturation predicted by different types of petrographic parameters (vitrinite reflectance and spectral fluorescence of telalginite), 2. reproducibility of the results for these maturation parameters obtained by different laboratories, and 3. improvements in the spectral fluorescence measurement obtained using modern detection systems in comparison with the results from historical round robin exercises.Mean random vitrinite reflectance measurements presented the highest level of reproducibility (group standard deviation 0.05) for low maturity and reproducibility diminished with increasing maturation (group standard deviation 0.12).Corrected fluorescence spectra, provided by 14 participants, showed a fair to good correspondence. Standard deviation of the mean values for spectral parameters was lowest for the low maturity sample but was also fairly low for higher maturity samples.A significant improvement in the reproducibility of corrected spectral fluorescence curves was obtained in the current exercise compared to a previous investigation of Toarcian organic matter spectra in a maturation series from the Paris Basin. This improvement is demonstrated by lower values of standard deviation and is interpreted to reflect better performance of newer photo-optical measuring systems.Fluorescence parameters measured here are in good agreement with vitrinite reflectance values for the least mature shale but indicate higher maturity than shown by vitrinite reflectance for the two more mature shales. This red shift in

  20. Enhanced efficiency of female-to-male HIV transmission in core groups in developing countries: the need to target men.

    Science.gov (United States)

    O'Farrell, N

    2001-02-01

    The spread of heterosexual HIV in developing countries is heterogeneous. Factors that explain the wide diversity of HIV prevalences in different countries are undetermined. International aid organizations currently appear to be focusing activities mainly on women rather than on men. To identify critical determinants contributing to the high rates of heterosexual HIV transmission in developing countries through a review of studies investigating HIV per-act transmission rates, and to discuss how these factors might be prioritized through HIV-prevention interventions. Studies investigating the per-act HIV transmission rate were identified through a MEDLINE search and a review of the abstracts of the Annual International AIDS Conferences. When the summary mean per-act HIV transmission rates were calculated, the ratio of female-to-male HIV transmission in developing countries compared with that in the developed world was 341, whereas that for male-to-female transmission was 2.9. Enhanced female-to-male HIV transmission in male core groups is a critical determinant of high-prevalence HIV epidemics among heterosexuals in developing countries. In addition to condom promotion, there is a need for an increased emphasis on HIV-prevention activities in men to decrease their susceptibility in developing countries, particularly in the countries most affected by the epidemic.

  1. Multi-Group Formulation of the Temperature-Dependent Resonance Scattering Model and its Impact on Reactor Core Parameters

    Energy Technology Data Exchange (ETDEWEB)

    Ghrayeb, Shadi Z. [Pennsylvania State Univ., University Park, PA (United States). Dept. of Mechanical and Nuclear Engineering; Ougouag, Abderrafi M. [Idaho National Laboratory (INL), Idaho Falls, ID (United States); Ouisloumen, Mohamed [Westinghouse Electric Company, Cranberry Township, PA (United States); Ivanov, Kostadin N. [Pennsylvania State Univ., University Park, PA (United States). Dept. of Mechanical and Nuclear Engineering

    2014-01-01

    A multi-group formulation for the exact neutron elastic scattering kernel is developed. It incorporates the neutron up-scattering effects, stemming from lattice atoms thermal motion and accounts for it within the resulting effective nuclear cross-section data. The effects pertain essentially to resonant scattering off of heavy nuclei. The formulation, implemented into a standalone code, produces effective nuclear scattering data that are then supplied directly into the DRAGON lattice physics code where the effects on Doppler Reactivity and neutron flux are demonstrated. The correct accounting for the crystal lattice effects influences the estimated values for the probability of neutron absorption and scattering, which in turn affect the estimation of core reactivity and burnup characteristics. The results show an increase in values of Doppler temperature feedback coefficients up to -10% for UOX and MOX LWR fuels compared to the corresponding values derived using the traditional asymptotic elastic scattering kernel. This paper also summarizes the results done on this topic to date.

  2. IUPAC-NIST Solubility Data Series. 85. Transition and 12-14 Main Group Metals, Lanthanide, Actinide, and Ammonium Halates

    Science.gov (United States)

    Miyamoto, Hiroshi

    2008-06-01

    This paper is the fourth and final volume in the halate solubility series. The solubility data for halates of transition metals, lanthanides, actinides, ammonium, and metallic elements of the main groups 12-14 are reviewed. Where appropriate, binary, ternary, and multicomponent systems are critically evaluated. Most of the solubility results were obtained in water or aqueous solutions of electrolytes. The solubility in organic solvents and aqueous-organic solvent mixtures is also collected in this volume. All these data were critically examined for their reliability. The best values were selected on the basis of critical evaluations and presented in tabular form. Fitting equations and graphical plots are also provided. When numerical data were not reported in an original publication, they were read out from figures and digitized by the compilers. The quantities, units, and symbols used in this volume are in accord with IUPAC recommendations. We always reported the original data and, if necessary, transferred them into the IUPAC recommended units and symbols. The literature on the solubility data was researched through 2002. The halates of these metals play a role in industrial processes. For example, some halates are essential as catalysts, heat stabilizers, and blanching reagents for manufacturing polymer products such as textiles and resins. Some iodates are used in pyrotechnic compounds for weather modification and colored smoke generation. The nonlinear halate crystals are important in construction of optical devices.

  3. Validation of the ICF Core Set for Vocational Rehabilitation from the perspective of patients with spinal cord injury using focus groups.

    Science.gov (United States)

    Aiachini, Beatrice; Cremascoli, Sonia; Escorpizo, Reuben; Pistarini, Caterina

    2016-01-01

    The International Classification of Functioning, Disability and Health (ICF) Core Set for Vocational Rehabilitation is an application of the ICF of the World Health Organization with the purpose of identifying problems and resources relevant for people in a vocational rehabilitation given a health condition. The objective of the study was to validate the Comprehensive ICF Core Set for Vocational Rehabilitation from the perspective of patients with spinal cord injury (SCI). The specific aims were to explore the aspects of functioning and health important to patients with SCI regarding return to work and to examine to what extent these aspects are represented by the current version of the Comprehensive ICF Core Set for Vocational Rehabilitation. Focus group interviews were conducted. The sampling of patients followed the maximum variation strategy. Sample size satisfied saturation criterion. The focus groups were digitally recorded and transcribed verbatim. The meaning condensation procedure was used for the data analysis. After qualitative data analysis, the resulting concepts were linked to ICF categories according to established linking rules. Twenty-four SCI patients participated in seven focus groups. Sixty-three ICF categories out of 90 ICF categories contained in the Comprehensive ICF Core Set for Vocational Rehabilitation were reported by the patients. Forty-two additional categories that are not covered in the Comprehensive ICF Core Set for Vocational Rehabilitation were found but adding the health condition-specific ICF Core Set for SCI in long-term context, only 11 categories were not covered. The existing version of the Comprehensive ICF Core Set for Vocational Rehabilitation was confirmed almost entirely by the focus groups to explore the vocational situation of patients with SCI. Implications for Rehabilitation Validation of the ICF Core Set for Vocational Rehabilitation as a useful tool to facilitate social reintegration and rehabilitation of patients

  4. Caregiver Use of the Core Components of Technology-Enhanced Helping the Noncompliant Child: A Case Series Analysis of Low-Income Families.

    Science.gov (United States)

    Anton, Margaret T; Jones, Deborah J; Cuellar, Jessica; Forehand, Rex; Gonzalez, Michelle; Honeycutt, Amanda; Khavjou, Olga; Newey, Greg; Edwards, Alex; Jacobs, Mary; Pitmman, Sarah

    2016-05-01

    Children from low-income families are more likely to develop early-onset disruptive behavior disorders (DBDs) compared to their higher income counterparts. Low-income families of children with early-onset DBDs, however, are less likely to engage in the standard-of-care treatment, behavioral parent training (BPT), than families from other sociodemographic groups. Preliminary between-group findings suggested technology-enhanced BPT was associated with increased engagement and boosted treatment outcomes for low-income families relative to standard BPT. The current study used a case series design to take this research a step further by examining whether there was variability in use of, and reactions to, the smartphone enhancements within technology-enhanced BPT and the extent to which this variability paralleled treatment outcome. Findings provide a window into the uptake and use of technology-enhanced service delivery methods among low-income families, with implications for the broader field of children's mental health.

  5. A new family of four-ring bent-core nematic liquid crystals with highly polar transverse and end groups

    Directory of Open Access Journals (Sweden)

    Kalpana Upadhyaya

    2013-01-01

    Full Text Available Non-symmetrically substituted four-ring achiral bent-core compounds with polar substituents, i.e.., chloro in the bent or transverse direction in the central core and cyano in the lateral direction at one terminal end of the molecule, are designed and synthesized. These molecules possess an alkoxy chain attached at only one end of the bent-core molecule. The molecular structure characterization is consistent with data from elemental and spectroscopic analysis. The materials thermal behaviour and phase characterization have been investigated by differential scanning calorimetry and polarizing microscopy. All the compounds exhibit a wide-ranging monotropic nematic phase.

  6. Biomembrane disruption by silica-core nanoparticles: effect of surface functional group measured using a tethered bilayer lipid membrane.

    Science.gov (United States)

    Liu, Ying; Zhang, Zhen; Zhang, Quanxuan; Baker, Gregory L; Worden, R Mark

    2014-01-01

    Engineered nanomaterials (ENM) have desirable properties that make them well suited for many commercial applications. However, a limited understanding of how ENM's properties influence their molecular interactions with biomembranes hampers efforts to design ENM that are both safe and effective. This paper describes the use of a tethered bilayer lipid membrane (tBLM) to characterize biomembrane disruption by functionalized silica-core nanoparticles. Electrochemical impedance spectroscopy was used to measure the time trajectory of tBLM resistance following nanoparticle exposure. Statistical analysis of parameters from an exponential resistance decay model was then used to quantify and analyze differences between the impedance profiles of nanoparticles that were unfunctionalized, amine-functionalized, or carboxyl-functionalized. All of the nanoparticles triggered a decrease in membrane resistance, indicating nanoparticle-induced disruption of the tBLM. Hierarchical clustering allowed the potency of nanoparticles for reducing tBLM resistance to be ranked in the order amine>carboxyl~bare silica. Dynamic light scattering analysis revealed that tBLM exposure triggered minor coalescence for bare and amine-functionalized silica nanoparticles but not for carboxyl-functionalized silica nanoparticles. These results indicate that the tBLM method can reproducibly characterize ENM-induced biomembrane disruption and can distinguish the BLM-disruption patterns of nanoparticles that are identical except for their surface functional groups. The method provides insight into mechanisms of molecular interaction involving biomembranes and is suitable for miniaturization and automation for high-throughput applications to help assess the health risk of nanomaterial exposure or identify ENM having a desired mode of interaction with biomembranes. © 2013. Published by Elsevier B.V. All rights reserved.

  7. NOVEL HYPERBRANCHED POLY(PHENYLENE OXIDE)S WITH PHENOLIC TERMINAL GROUPS: EFFECTS OF REACTION TIME AND CORE MOLECULES ON THE MOLECULAR WEIGHT AND POLYDISPERSITY

    Institute of Scientific and Technical Information of China (English)

    Ji-gui Zhang; Hai-qiao Wang; Xiao-yu Li

    2006-01-01

    A novel hyperbranched poly(phenylene oxide) (HPPO) with phenolic terminal groups was prepared from 4-bromo-4′,4″-dihydroxytriphenylmethane as AB2 monomer in dimethylsulfoxide (DMSO) via a modified Ullmann reaction.The molecular weight and polydispersity (PD) of the resulting polymers increased with increasing reaction time. In the presence of core molecules (bisphenol A and 1,3,5-trihydroxybenzene), which have the similar molecular backbones to the reactive monomer, the molecular weight could be controlled by varying the core-to-monomer ratio. Incorporation of a very small amount of core molecules could lead to a higher molecular weight as compared with that without the addition of core molecules. However, when the core content reached certain extent, the molecular weight would decrease with the further increase in the core content. A new similar behavior of control over the PD was also obtained. The resulting polymers were characterized by 1H-NMR, 13C-NMR, FT-IR, and GPC.

  8. Effects of electron-withdrawing group and electron-donating core combinations on physical properties and photovoltaic performance in D-pi-A star-shaped small molecules

    NARCIS (Netherlands)

    Luponosov, Yuriy N.; Min, Jie; Solodukhin, Alexander N.; Kozlov, Oleg V.; Obrezkova, Marina A.; Peregudova, Svetlana M.; Ameri, Tayebeh; Chvalun, Sergei N.; Pshenichnikov, Maxim S.; Brabec, Christoph J.; Ponomarenko, Sergei A.

    2016-01-01

    The first representatives of star-shaped molecules having 3-alkylrhodanine (alkyl-Rh) electron-withdrawing groups, linked through bithiophene pi-spacer with electron-donating either triphenylamine (TPA) or tris(2-methoxyphenyl)amine (m-TPA) core were synthesized. The physical properties and photovol

  9. Polycomb group proteins Ring1A/B are functionally linked to the core transcriptional regulatory circuitry to maintain ES cell identity

    NARCIS (Netherlands)

    Endoh, M.; Endo, T.A.; Endoh, T.; Fujimura, Y.; Ohara, O.; Toyoda, T.; Otte, A.P.; Okano, M.; Brockdorff, N.; Vidal, M.; Koseki, H.

    2008-01-01

    The Polycomb group (PcG) proteins mediate heritable silencing of developmental regulators in metazoans, participating in one of two distinct multimeric protein complexes, the Polycomb repressive complexes 1 (PRC1) and 2 (PRC2). Although PRC2 has been shown to share target genes with the core transcr

  10. Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core.

    Science.gov (United States)

    Wood, Michael R; Noetzel, Meredith J; Engers, Julie L; Bollinger, Katrina A; Melancon, Bruce J; Tarr, James C; Han, Changho; West, Mary; Gregro, Alison R; Lamsal, Atin; Chang, Sichen; Ajmera, Sonia; Smith, Emery; Chase, Peter; Hodder, Peter S; Bubser, Michael; Jones, Carrie K; Hopkins, Corey R; Emmitte, Kyle A; Niswender, Colleen M; Wood, Michael W; Duggan, Mark E; Conn, P Jeffrey; Bridges, Thomas M; Lindsley, Craig W

    2016-07-01

    This Letter describes the chemical optimization of a novel series of M4 positive allosteric modulators (PAMs) based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core, identified from an MLPCN functional high-throughput screen. The HTS hit was potent and selective, but not CNS penetrant. Potency was maintained, while CNS penetration was improved (rat brain:plasma Kp=0.74), within the original core after several rounds of optimization; however, the thieno[2,3-d]pyrimidine core was subject to extensive oxidative metabolism. Ultimately, we identified a 6-fluoroquinazoline core replacement that afforded good M4 PAM potency, muscarinic receptor subtype selectivity and CNS penetration (rat brain:plasma Kp>10). Moreover, this campaign provided fundamentally distinct M4 PAM chemotypes, greatly expanding the available structural diversity for this exciting CNS target.

  11. ENVIRONMENTAL TECHNOLOGY VERIFICATION, TEST REPORT OF CONTROL OF BIOAEROSOLS IN HVAC SYSTEMS, FILTRATION GROUP, AEROSTAR "C-SERIES" POLYESTER PANEL FILTER

    Science.gov (United States)

    The Environmental Technology Verification report discusses the technology and performance of the AeroStar "C-Series" Polyester Panel Filter air filter for dust and bioaerosol filtration manufactured by Filtration Group. The pressure drop across the filter was 126 Pa clean and 267...

  12. Perceived pros and cons of smoking and quitting in hard-core smokers: a focus group study.

    NARCIS (Netherlands)

    Bommelé, J.; Schoenmakers, T.M.; Kleinjan, M.; Straaten, B. van; Wits, E.; Snelleman, M.; Mheen, D. van de

    2014-01-01

    Background: In the last decade, so-called hard-core smokers have received increasing interest in research literature. For smokers in general, the study of perceived costs and benefits (or ‘pros and cons’) of smoking and quitting is of particular importance in predicting motivation to quit and actual

  13. Perceived pros and cons of smoking and quitting in hard-core smokers: A focus group study

    NARCIS (Netherlands)

    J. Bommelé (Jeroen); T.M. Schoenmakers (Tim); M. Kleinjan (Marloes); B. van Straaten (Barbara); E. Wits (Elske); M. Snelleman (Michelle); H. van de Mheen (Dike)

    2014-01-01

    textabstractBackground: In the last decade, so-called hard-core smokers have received increasing interest in research literature. For smokers in general, the study of perceived costs and benefits (or 'pros and cons') of smoking and quitting is of particular importance in predicting motivation to qui

  14. Perceived pros and cons of smoking and quitting in hard-core smokers: a focus group study.

    NARCIS (Netherlands)

    Bommelé, J.; Schoenmakers, T.M.; Kleinjan, M.; Straaten, B. van; Wits, E.; Snelleman, M.; Mheen, D. van de

    2014-01-01

    Background: In the last decade, so-called hard-core smokers have received increasing interest in research literature. For smokers in general, the study of perceived costs and benefits (or ‘pros and cons’) of smoking and quitting is of particular importance in predicting motivation to quit and actual

  15. Empowering Grandparents Raising Grandchildren: A Training Manual for Group Leaders. Springer Series on Life Styles and Issues in Aging.

    Science.gov (United States)

    Cox, Carole B.

    Noting that grandparents in the parenting role are often overwhelmed by the problems of their children, grandchildren, and the social milieu in which they live, this manual presents a 14-session workshop series designed to empower grandparents who are raising their grandchildren alone. Designed to complement "To Grandmother's House We Go and…

  16. An ethnomedicinal study of the Seri people; a group of hunter-gatherers and fishers native to the Sonoran Desert.

    Science.gov (United States)

    Narchi, Nemer E; Aguilar-Rosas, Luis Ernesto; Sánchez-Escalante, José Jesús; Waumann-Rojas, Dora Ofelia

    2015-08-11

    Worldwide, coastal communities' ethnomedicinal knowledge has been sporadically recorded and poorly understood. Based on the ethnomedicinal knowledge of the Seri people; a hunting-gathering and fishing society of Northwestern Mexico, this study assesses a) the biological richness of Seri ethnomedicinal knowledge, b) the fidelity level of Seri remedies, and c) the association between gender, age, years of formal schooling and Seri ethnomedicinal knowledge. To assess the degree of ethnomedicinal knowledge proficiency, we conducted 75 open-ended semi-structured interviews collecting information on ethnomedicinal knowledge of marine and terrestrial organisms and the socio-demographic profile of each collaborator. With the support of primary collaborators, we collected the materials to be used as stimuli along our interviews. A correlation analysis was used to determine the relationship between gender, literacy and age with the ethnomedicinal knowledge proficiency. A paired t-test was used to determine differences in the number of remedies known by gender among members of the Seri community. A total of 28 medicinal specimens were presented as stimuli material. Marine remedies (12 species), were represented by 4 algae, 3 mollusks, 3 echinoderms, on reptile, and one annelid. Terrestrial plants (13 species) were distributed in 12 families. About 40 % of marine preparations used the organism in whole. In contrast, 29 % of of the remedies involving plants made use of leafy branches. Stimuli materials are used against 17 ailments mainly, being diarrhea, colds, menstrual problems, and swelling the ailments against most organisms (44 %) are used for. Marine organisms presented higher fidelity level values overall, suggesting that lower fidelity levels in terrestrial plants reflect a process of continuous and ongoing experimentation with easily accessible biological materials. Highest fidelity level values were recorded for Atriplex barclayana (93.87 %) Batis maritima (84

  17. Invariant differential operators on H-type groups and discrete components in restrictions of complementary series of rank one semisimple groups

    DEFF Research Database (Denmark)

    Möllers, Jan; Ørsted, Bent; Zhang, Genkai

    2016-01-01

    on the nilpotent radicals $N$ and $N_1$ of the minimal parabolics in $G$ and $G_1$, respectively. The groups $N$ and $N_1$ are of H-type and we construct explicitly invariant differential operators between $N$ and $N_1$. These operators induce the projections onto the discrete components. Our construction...... of the invariant differential operators is carried out uniformly in the framework of H-type groups and also works for those H-type groups which do not occur as nilpotent radical of a parabolic subgroup in a semisimple group....

  18. Monte Carlo and theoretical calculations of the first four perturbation coefficients in the high temperature series expansion of the free energy for discrete and core-softened potential models

    Science.gov (United States)

    Zhou, Shiqi; Solana, J. R.

    2013-06-01

    The first four perturbation coefficients in the expansion of the Helmholtz free energy in power series of the inverse of the reduced temperature for a number of potential models with hard-sphere cores plus core-softened and discontinuous tails are obtained from Monte Carlo simulations. The potential models considered include square-well, double square-well, and square-shoulder plus square-well, with different potential parameters. These simulation data are used to evaluate the performance of a traditional macroscopic compressibility approximation (MCA) for the second order coefficient and a recent coupling parameter series expansion (CPSE) for the first four coefficients. Comprehensive comparison indicates the incapability of the MCA for the second order coefficient in most non-stringent situations, and significance of the CPSE in accurately calculating these four coefficients.

  19. Two- and Three-Dimensional Multi-Physics Simulations of Core Collapse Supernovae: A Brief Status Report and Summary of Results from the "Oak Ridge" Group

    CERN Document Server

    Mezzacappa, Anthony; Lentz, Eric J; Hix, W Raphael; Messer, O E Bronson; Harris, J Austin; Lingerfelt, Eric J; Endeve, Eirik; Yakunin, Konstantin N; Blondin, John M; Marronetti, Pedro

    2014-01-01

    We summarize the results of core collapse supernova theory from one-, two-, and three-dimensional models and provide a snapshot of the field at this time. We also present results from the "Oak Ridge" group in this context. Studies in both one and two spatial dimensions define the necessary} physics that must be included in core collapse supernova models: a general relativistic treatment of gravity (at least an approximate one), spectral neutrino transport, including relativistic effects such as gravitational redshift, and a complete set of neutrino weak interactions that includes state-of-the-art electron capture on nuclei and energy-exchanging scattering on electrons and nucleons. Whether or not the necessarily approximate treatment of this physics in current models that include it is sufficient remains to be determined in the context of future models that remove the approximations. We summarize the results of the Oak Ridge group's two-dimensional supernova models. In particular, we demonstrate that robust n...

  20. Exact conditional distribution of a three-phase invariant in the space group P1. I. Derivation and simplification of the Fourier series.

    Science.gov (United States)

    Shmueli, U; Rabinovich, S; Weiss, G H

    1989-06-01

    An exact expression is derived for the conditional probability density function of a three-phase invariant and the general result is applied to the space group P1. The expression for the conditional density is given in terms of a sixfold Fourier series. A straightforward numerical evaluation of this series, without further analysis, is extremely time consuming. Much of the present paper is therefore devoted to an exposition of symmetries hidden in the various summations. The computational effort required for the evaluation of the above expression is thereby reduced to manageable proportions in a number of interesting cases. Results of numerical computations of the exact conditional density are given in the second paper in this series. It is also shown that the exact expression for the conditional probability reduces to that given by Cochran [Acta Cryst. (1955), 8, 473-478].

  1. Phenyl Groups Result in the Highest Benzene Storage and Most Efficient Desulfurization in a Series of Isostructural Metal-Organic Frameworks.

    Science.gov (United States)

    He, Wen-Wen; Yang, Guang-Sheng; Tang, Yu-Jia; Li, Shun-Li; Zhang, Shu-Ran; Su, Zhong-Min; Lan, Ya-Qian

    2015-06-26

    A series of isoreticular metal-organic frameworks (MOFs; NENU-511-NENU-514), which all have high surface areas and strong adsorption capacities, have been successfully constructed by using mixed ligands. NENU-513 has the highest benzene capacity of 1687 mg g(-1) at 298 K, which ranks as the top MOF material among those reported up to now. This NENU series has been used for adsorptive desulfurization because of its permanent porosity. The results indicate that this series has a higher adsorptive efficiency in the removal of organosulfur compounds than other MOF materials, especially NENU-511, which has the highest adsorptive efficiency in the ambient atmosphere. This study proves that the design and synthesis of targeted MOFs with higher surface areas and with functional groups present is an efficient method to enhance benzene-storage capacity and the adsorption of organosulfur compounds. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. A journey from the outskirts to the cores of groups : I. Color- and mass-segregation in 20K-zCOSMOS groups

    NARCIS (Netherlands)

    Presotto, V.; Iovino, A.; Scodeggio, M.; Cucciati, O.; Knobel, C.; Bolzonella, M.; Oesch, P.; Finoguenov, A.; Tanaka, M.; Kovac, K.; Peng, Y.; Zamorani, G.; Bardelli, S.; Pozzetti, L.; Kampczyk, P.; Lopez-Sanjuan, C.; Vergani, D.; Zucca, E.; Tasca, L. A. M.; Carollo, C. M.; Contini, T.; Kneib, J. -P.; Le Fevre, O.; Lilly, S.; Mainieri, V.; Renzini, A.; Bongiorno, A.; Caputi, K.; de la Torre, S.; de Ravel, L.; Franzetti, P.; Garilli, B.; Lamareille, F.; Le Borgne, J. -F.; Le Brun, V.; Maier, C.; Mignoli, M.; Pello, R.; Perez-Montero, E.; Ricciardelli, E.; Silverman, J. D.; Tresse, L.; Barnes, L.; Bordoloi, R.; Cappi, A.; Cimatti, A.; Coppa, G.; Koekemoer, A. M.; McCracken, H. J.; Moresco, M.; Nair, P.; Welikala, N.

    2012-01-01

    Context. Studying theevolution of galaxies located within groups may have important implications for our understanding of the global evolution of the galaxy population as a whole. The fraction of galaxies bound in groups at z ~ 0 is as high as 60% and therefore any mechanism (among the many suggeste

  3. DFT study of structure, IR and Raman spectra of the first generation dendron built from cyclotriphosphazene core with terminal carbamate and ester groups

    Science.gov (United States)

    Furer, V. L.; Vandyukov, A. E.; Fuchs, S.; Majoral, J. P.; Caminade, A. M.; Kovalenko, V. I.

    2012-06-01

    The FTIR and FT-Raman spectra of the first generation dendron built from the cyclotriphosphazene core, five arms sbnd Osbnd C6H4sbnd CHdbnd Nsbnd N(CH3)sbnd P(S)rbond2 with ten carbamate terminal groups and one ester function Gv1 have been recorded. The IR and Raman spectra of the zero generation dendron Gv0 and first generation dendrimer G1 with the same core and terminal groups were also examined. The structural optimization and normal mode analysis were performed for dendron Gv1 on the basis of the density functional theory (DFT). The calculated geometrical parameters and harmonic vibrational frequencies are predicted in a good agreement with the experimental data. It was found that Gv1 has a concave lens structure with planar sbnd Osbnd C6H4sbnd CHdbnd Nsbnd N(CH3)sbnd P(S)rbond2 fragments and slightly non-planar cyclotriphosphazene core. The carbamate groups attached to different arms show significant deviations from a symmetrical arrangement relative to the local planes of repeating units. The experimental IR spectrum of Gv1 dendron was interpreted by means of potential energy distributions. The strong band 1604 cm-1 shows marked changes of the optical density in dependence of the carbamate, ester or azomethyne substituents in the aromatic ring. The frequencies of ν(Nsbnd H) and ν(Cdbnd O) bands in the IR spectra reveal the presence of the different types of H-bonds in the studied dendrimers.

  4. Core competencies in internal medicine.

    Science.gov (United States)

    Porcel, José Manuel; Casademont, Jordi; Conthe, Pedro; Pinilla, Blanca; Pujol, Ramón; García-Alegría, Javier

    2012-06-01

    The working group on Competencies of Internal Medicine from the Spanish Society of Internal Medicine (SEMI) proposes a series of core competencies that we consider should be common to all European internal medicine specialists. The competencies include aspects related to patient care, clinical knowledge, technical skills, communication skills, professionalism, cost-awareness in medical care and academic activities. The proposal could be used as a working document for the Internal Medicine core curriculum in the context of the educational framework of medical specialties in Europe.

  5. A Comparative Study of Effectiveness of Peer Assessment of Individuals' Contributions to Group Projects in Undergraduate Construction Management Core Units

    Science.gov (United States)

    Jin, Xiao-Hua

    2012-01-01

    In recent years, various forms of group work have been introduced in university courses across various subject domains, including construction management courses. Although the use of group work in higher education has sound pedagogical reasons and advantages, group work has its own drawbacks. Therefore, the acceptance by students and the success…

  6. International Earth Science Constellation Mission Operations Working Group September 27-29, 2016 Aqua Spring 2017 IAM Series

    Science.gov (United States)

    Good, Susan M.

    2016-01-01

    This Aqua Spring 2017 IAM Series powerpoint presentation will be presented at the MOWG meeting in Albuquerque, NM. Topics to be discussed are: recap Aqua 2016 IAM campaign maneuver results and post 2016 IAM MLT evolution; current DMU strategy; 2017 IAM campaign dates and planning; Aqua latest lifetime MLT team predictions. Susan Good is a contractor who supports David Tracewell in code 595 therefore this is being routed through 595. Eric Moyer, ESMO Deputy Project Manager-Technical has reviewed and approved this presentation.

  7. Application of Pool group technology in EPC core network%池组(Pool)化技术在EPC核心网中的应用探讨

    Institute of Scientific and Technical Information of China (English)

    李军

    2013-01-01

    MME Pool technology as an important means of EPC core network security, can effectively help mobile operators to solve the network load balancing and disaster recovery in the LTE core network, to maximize network resource value, to provide customers with better service quality. The EPC core network architecture and the Pool group in EPC core network applications are introduced in this paper. The MME Pool network planning principles are summed up based on the application analysis of MME Pool load balancing and disaster recovery. A reference is provided for the MME Pool deployment and application in this article.%MME Pool技术作为EPC核心网络安全保障的一个重要手段,能够有效的帮助移动运营商解决LTE核心网络中存在的负载均衡和容灾备份问题,最大化网络资源价值,为客户提供更好的服务质量。文章首先对池组化在EPC核心网的应用进行了介绍,通过对MME Pool技术的负载均衡和容灾备份应用分析,总结出MME Pool的组网规划原则,为MME Pool的部署和应用提供了参考。

  8. A homologous series of regioselectively tetradeprotonated group 8 metallocenes: new inverse crown ring compounds synthesized via a mixed sodium-magnesium tris(diisopropylamide) synergic base.

    Science.gov (United States)

    Andrikopoulos, Prokopis C; Armstrong, David R; Clegg, William; Gilfillan, Carly J; Hevia, Eva; Kennedy, Alan R; Mulvey, Robert E; O'Hara, Charles T; Parkinson, John A; Tooke, Duncan M

    2004-09-22

    Subjecting ferrocene, ruthenocene, or osmocene to the synergic amide base sodium-magnesium tris(diisopropylamido) affords a unique homologous series of metallocene derivatives of general formula [(M(C(5)H(3))(2))Na(4)Mg(4)(i-Pr(2)N)(8)] (where M = Fe (1), Ru (2), or Os (3)). X-ray crystallographic studies of 1-3 reveal a common molecular "inverse crown" structure comprising a 16-membered [(NaNMgN)(4)](4+) "host" ring and a metallocenetetraide [M(C(5)H(3))(2)](4-) "guest" core, the cleaved protons of which are lost selectively from the 1, 1', 3, and 3'-positions. Variable-temperature NMR spectroscopic studies indicate that 1, 2, and 3 each exist as two distinct interconverting conformers in arene solution, the rates of exchange of which have been calculated using coalescence and EXSY NMR measurements.

  9. Surface-pressure Distributions on a Systematic Group of NACA 1-series Cowlings with and Without Spinners

    Science.gov (United States)

    Boswinkle, Robert W JR; Keith, Arvid L JR

    1948-01-01

    A method for calculating the flow fields of axially symmetric bodies from their pressure distributions is reported in NACA RM No. L8I17. In order to facilitate application of this method to the important case of the cowling-spinner combination, for use in the design of propellers, the present paper presents static-pressure distributions on the tops of 79 high-critical-speed NACA 1-series cowling-spinner combinations over wide ranges of inlet-velocity ratio at angles of attack of 0 degrees, 2 degrees, 4 degrees, and 6 degrees. Static-pressure distributions around the nose sections of several cowlings are given in greater detail to aid in estimating the pressures near the stagnation points and to show the effect of changes in the internal lip shape. The effects of the operation of a typical propeller on the surface pressures on the cowling are shown for one configuration. The pressure distributions over the nine NACA 1-series nose inlets used as the basic components of these combinations are also presented ro supplement the existing open-nose-cowling data of NACA ACR No. L5F30a which are applicable to the case of the rotating cowling.

  10. Magnetic adsorbent of Fe3O4@SiO2 core-shell nanoparticles modified with thiol group for chloroauric ion adsorption

    Science.gov (United States)

    Roto, Roto; Yusran, Yusran; Kuncaka, Agus

    2016-07-01

    The magnetic adsorbent of Fe3O4@SiO2 core-shell nanoparticles modified with thiol group was synthesized for chloroauric ([AuCl4]-) adsorption. The Fe3O4 nanoparticles were prepared by co-precipitation method under mechanical stirring and coated with SiO2 by acid hydrolysis of Na2SiO3 under N2 purging. The coating of Fe3O4 nanoparticles with SiO2 prevents particles' agglomeration by forming Fe3O4 Fe3O4 Fe3O4@SiO2 core-shell and avoids dissolution of the Fe3O4 core in the acidic medium. The coated Fe3O4 particle was modified with a thiol group using 3-mercaptopropyltrimethoxysilane via silanization reaction. The results suggest that SiO2-coated Fe3O4 particles have a size of 10-20 nm. The FTIR and EDX data indicate that the thiol groups are successfully attached to the surface of the nanoparticles. The [AuCl4]- ion adsorption by the Fe3O4@SiO2 core-shell nanoparticles followed Langmuir isotherm model with a maximum adsorption capacity of 115 mg/g and free energy (ΔG°) of 24.8 kJ/mol. The thiourea solution can be used to desorb most of the adsorbed [AuCl4]- ion. The adsorption using magnetic compounds provides easy access to the separation for both preparation and recovery.

  11. Outcomes of polio eradication activities in Uttar Pradesh, India: the Social Mobilization Network (SM Net and Core Group Polio Project (CGPP

    Directory of Open Access Journals (Sweden)

    Singh Vibha

    2011-05-01

    Full Text Available Abstract Background The primary strategy to interrupt transmission of wild poliovirus in India is to improve supplemental immunization activities and routine immunization coverage in priority districts with a focus on 107 high-risk blocks of western Uttar Pradesh and central Bihar. Villages or urban areas with a history of wild poliovirus transmission, or hard-to-reach or resistant populations are categorized as high-risk areas within blocks. The Social Mobilization Network (SM Net was formed in Uttar Pradesh in 2003 to support polio eradication efforts through improved planning, implementation and monitoring of social mobilization activities in those high-risk areas. In this paper, we examine the vaccination outcomes in districts of SM Net where the CORE Group works. Methods We carried out a secondary data analysis of routine monitoring information collected by the SM Net and the Government of India. These data include information about vaccination outcomes in SM Net areas and non-SM Net areas within the districts where the CORE Group operates. Statistical analysis was used to compare, between SM Net and non-SM Net areas, vaccination outcomes considered sensitive to social mobilization efforts of the SM Net. We employed Generalized Estimating Equations (GEE statistical method to account for Intra-cluster Correlation (ICC, and used 'Quasi-likelihood under the independence model criterion (QIC' as the model selection method. Results Vaccination outcomes in SM Net areas were as high as or higher than in non-SM Net areas. There was considerable variation in vaccination outcomes between districts. Conclusions While not conclusive, the results suggest that the social mobilization efforts of the SM Net and the CORE Group are helping to increase vaccination levels in high-risk areas of Uttar Pradesh. Vaccination outcomes in CORE Group areas were equal or higher than in non-CORE, non-SM Net areas. This occurred even though SM Net areas are those with

  12. Solution processable diketopyrrolopyrrole (DPP cored small molecules with BODIPY end groups as novel donors for organic solar cells

    Directory of Open Access Journals (Sweden)

    Diego Cortizo-Lacalle

    2014-11-01

    Full Text Available Two novel triads based on a diketopyrrolopyrrole (DPP central core and two 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY units attached by thiophene rings have been synthesised having high molar extinction coefficients. These triads were characterised and used as donor materials in small molecule, solution processable organic solar cells. Both triads were blended with PC71BM as an acceptor in different ratios by wt % and their photovoltaic properties were studied. For both the triads a modest photovoltaic performance was observed, having an efficiency of 0.65%. Moreover, in order to understand the ground and excited state properties and vertical absorption profile of DPP and BODIPY units within the triads, theoretical DFT and TDDFT calculations were performed.

  13. Solution processable diketopyrrolopyrrole (DPP) cored small molecules with BODIPY end groups as novel donors for organic solar cells.

    Science.gov (United States)

    Cortizo-Lacalle, Diego; Howells, Calvyn T; Pandey, Upendra K; Cameron, Joseph; Findlay, Neil J; Inigo, Anto Regis; Tuttle, Tell; Skabara, Peter J; Samuel, Ifor D W

    2014-01-01

    Two novel triads based on a diketopyrrolopyrrole (DPP) central core and two 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) units attached by thiophene rings have been synthesised having high molar extinction coefficients. These triads were characterised and used as donor materials in small molecule, solution processable organic solar cells. Both triads were blended with PC71BM as an acceptor in different ratios by wt % and their photovoltaic properties were studied. For both the triads a modest photovoltaic performance was observed, having an efficiency of 0.65%. Moreover, in order to understand the ground and excited state properties and vertical absorption profile of DPP and BODIPY units within the triads, theoretical DFT and TDDFT calculations were performed.

  14. Platinum-group elements in the cores of potassium feldspar spherules from the Cretaceous-Tertiary boundary at Caravaca (Spain

    Directory of Open Access Journals (Sweden)

    Palomo, I.

    1994-04-01

    Full Text Available The abundant spherules present in the Cretaceous-Tertiary boundary layer at Caravaca are diagenetically transformed to potassium feldspar. Before our study no possible relicts of the precursor material had been reported. but in this paper we describe the presence of cores in these spherules that could represent a relict of the «unknown precursor». These cores are made up of C mixed with Si. Mg. AL Cr. Ca among other elements. Laser Ablation System analysis also reveals an enrichment in pe;E could suggest an extraterrestrial origin for this material. PI. Pd and Ir do not show a chondritic ratio: however. asevere modification of their concentration could be expected during the early diagenetic processes.Las esférulas existentes en la lámina de sedimento del tránsito Cretácico-Terciario de la sección de Caravaca han sido transformadas diagenéticamente a feldespato potásico. En este trabajo se describe la existencia de núcleos encontrados en el interior de las esférulas. los cuales' pueden representar relictos del material precursor. Dichos núcleos están constituidos por C. Si. Mg, AL Cr y Ca entre otros elementos. Se pone de relieve, por vez primera, su notable enriquecimiento en elementos del grupo del platino, cuyas relaciones no condríticas pueden ser debidas a la existencia de importantes modificaciones en su concentración inicial causadas por los procesos diagenéticos y por la existencia de materia orgánica.

  15. A core phylogeny of Dictyostelia inferred from genomes representative of the eight major and minor taxonomic divisions of the group.

    Science.gov (United States)

    Singh, Reema; Schilde, Christina; Schaap, Pauline

    2016-11-17

    Dictyostelia are a well-studied group of organisms with colonial multicellularity, which are members of the mostly unicellular Amoebozoa. A phylogeny based on SSU rDNA data subdivided all Dictyostelia into four major groups, but left the position of the root and of six group-intermediate taxa unresolved. Recent phylogenies inferred from 30 or 213 proteins from sequenced genomes, positioned the root between two branches, each containing two major groups, but lacked data to position the group-intermediate taxa. Since the positions of these early diverging taxa are crucial for understanding the evolution of phenotypic complexity in Dictyostelia, we sequenced six representative genomes of early diverging taxa. We retrieved orthologs of 47 housekeeping proteins with an average size of 890 amino acids from six newly sequenced and eight published genomes of Dictyostelia and unicellular Amoebozoa and inferred phylogenies from single and concatenated protein sequence alignments. Concatenated alignments of all 47 proteins, and four out of five subsets of nine concatenated proteins all produced the same consensus phylogeny with 100% statistical support. Trees inferred from just two out of the 47 proteins, individually reproduced the consensus phylogeny, highlighting that single gene phylogenies will rarely reflect correct species relationships. However, sets of two or three concatenated proteins again reproduced the consensus phylogeny, indicating that a small selection of genes suffices for low cost classification of as yet unincorporated or newly discovered dictyostelid and amoebozoan taxa by gene amplification. The multi-locus consensus phylogeny shows that groups 1 and 2 are sister clades in branch I, with the group-intermediate taxon D. polycarpum positioned as outgroup to group 2. Branch II consists of groups 3 and 4, with the group-intermediate taxon Polysphondylium violaceum positioned as sister to group 4, and the group-intermediate taxon Dictyostelium polycephalum

  16. Validation and Verification the Expanded Table for Transition Metal Carbonyl and Main Group Element Cluster Series which obey the 18-Electron and 8-Electron (octet Rules respectively

    Directory of Open Access Journals (Sweden)

    Enos Masheija Kiremire

    2014-12-01

    Full Text Available The transition metal carbonyl clusters and Main group element clusters belong to natural series based on the number theory. The number series of the cluster series have been generated using the empirical formula k = ½ (E-V where k represents the linkages or bonds that glue together the cluster elements which obey the eighteen electron rule or the octet rule and E is related to the sum of eighteen electrons or the eight electrons and V is the sum of the valence electrons. An expanded cluster table been constructed to accommodate the analysis of medium to relatively large clusters of high nuclearity. Using the knowledge of k-value and the cluster table it is possible for a given cluster formula to be categorized into its type of series and its geometry deduced. This is relatively easy for simple to medium clusters. It is hoped that this simple approach to be adapted to categorize and deduce structures of clusters with high nuclearity. This approach to clusters using number theory will complement the existing clusters theories such as Wade-Mingos rules1-7, Jemmismno rules8-9 and topology rules10.

  17. Ethnic Groups: Negroes, Spanish Speaking, American Indians, and Eskimos. Part 4 of a Bibliographic Series on Meeting Special Educational Needs.

    Science.gov (United States)

    Poliakoff, Lorraine, Comp.

    This bibliography on ethnic groups cites 117 documents acquired and processed by the ERIC Clearinghouse on Teacher Education from July 1968 to December 1969. Organization is in three sections: Negroes--58 items; Spanish Speaking People--33 items; and American Indians and Eskimos--26 items. Each section is further broken down by document type:…

  18. Oxidation of ketone groups in transported biomass burning aerosol from the 2008 Northern California Lightning Series fires

    Science.gov (United States)

    Hawkins, Lelia N.; Russell, Lynn M.

    2010-11-01

    Submicron particles were collected from June to September 2008 in La Jolla, California to investigate the composition and sources of atmospheric aerosol in an anthropogenically-influenced coastal site. Factor analysis of aerosol mass spectrometry (AMS) and Fourier transform infrared (FTIR) spectroscopy measurements revealed that the two largest sources of submicron organic mass (OM) at the sampling site were (1) fossil fuel combustion associated with ship and diesel truck emissions near the ports of Los Angeles and Long Beach and (2) aged smoke from large wildfires burning in central and northern California. During non-fire periods, fossil fuel combustion contributed up to 95% of FTIR OM, correlated to sulfur, and consisted mostly of alkane (86%) and carboxylic acid groups (9%). During fire periods, biomass burning contributed up to 74% of FTIR OM, consisted mostly of alkane (48%), ketone (25%), and carboxylic acid groups (17%), and correlated to AMS-derived factors resembling brush fire smoke, wood smoldering and flaming particles, and biogenic secondary organic aerosol. The two AMS-derived biomass burning factors were identified as oxygenated and hydrocarbon biomass burning aerosol on the basis of spectral similarities to smoldering and flaming smoke particles, respectively. In addition, the ratio of oxygenated to hydrocarbon biomass burning OM shows a clear diurnal trend with an afternoon peak, consistent with photochemical oxidation. Back trajectory analysis indicates that 2-4-day old forest fire emissions include substantial ketone groups, which have both lower O/C and lower m/ z 44/OM fraction than carboxylic acid groups. Air masses with more than 4-day old emissions have higher carboxylic acid/ketone group ratios, showing that atmospheric processing of these ketone-containing organic aerosol particles results in increased m/ z 44 and O/C. These observations may provide functionally-specific evidence for the type of chemical processing that is responsible for

  19. Lepton Mixing Predictions from Infinite Group Series $D^{(1)}_{9n, 3n}$ with Generalized CP

    CERN Document Server

    Li, Cai-Chang; Ding, Gui-Jun

    2016-01-01

    We have performed a comprehensive analysis of the type D group $D^{(1)}_{9n, 3n}$ as flavor symmetry and the generalized CP symmetry. All possible residual symmetries and their consequences for the prediction of the mixing parameters are studied. We find that only one type of mixing pattern is able to accommodate the measured values of the mixing angles in both "direct" and "variant of semidirect" approaches, and four types of mixing patterns are phenomenologically viable in the "semidirect" approach. The admissible values of the mixing angles as well as CP violating phases are studied in detail for each case. It is remarkable that the first two smallest $D^{(1)}_{9n,3n}$ groups with $n=1, 2$ can fits the experimental data very well. The phenomenological predictions for neutrinoless double beta decay are discussed.

  20. Nutrition and fatty acid composition in different botanical groups of groundnut (Arachis hypogaea. L in ICRISAT mini core collection

    Directory of Open Access Journals (Sweden)

    Ganapati Mukri , ,Shridevi Jakkeral and H.L Nadaf

    2014-09-01

    Full Text Available Breeding for enhanced nutritional quality is need of the hour. India not only needs increased quantity of food to feed the growing population but also quality food to mitigate hidden hunger. Oil is the major energy source of the Indian diet. Chemical composition of oil decides its edible nature. Even in edible oil fatty acid composition in general and ratio of oleic acid to linoleic acid of the oil plays major role in deciding its quality. In India, availability of breeding line to improve groundnut oil quality is limited. Screening of different botanical group may give some idea about choice of material for further crop improvement program. In present study botanical group hypogaea, found to have higher amount of oleic acid and fastigiata group recorded high protein and oil content. Growing season also matters in the expression of different fatty acid. Rainy season is found to have better for the better expression of all studied traits.

  1. Technical report series on global modeling and data assimilation. Volume 5: Documentation of the AIRES/GEOS dynamical core, version 2

    Science.gov (United States)

    Suarez, Max J. (Editor); Takacs, Lawrence L.

    1995-01-01

    A detailed description of the numerical formulation of Version 2 of the ARIES/GEOS 'dynamical core' is presented. This code is a nearly 'plug-compatible' dynamics for use in atmospheric general circulation models (GCMs). It is a finite difference model on a staggered latitude-longitude C-grid. It uses second-order differences for all terms except the advection of vorticity by the rotation part of the flow, which is done at fourth-order accuracy. This dynamical core is currently being used in the climate (ARIES) and data assimilation (GEOS) GCMs at Goddard.

  2. Differential aspects of stroke and congestive heart failure in quality of life reduction: a case series with three comparison groups

    Science.gov (United States)

    2011-01-01

    Background To assess QOL of patients with stroke in comparison to other groups (caregivers and CHF patients), to identify which items of QOL are more affected on each group and what is the functional profile of patients with stroke. Methods Consecutive stroke or congestive heart failure (CHF) patients were evaluated and compared to their caregivers (caregivers). The NIH Stroke Scale (NIHSS) and EuroQoL-5D (EQ-5D) scale were applied. Results We evaluated 67 patients with stroke, 62 with CHF and 67 caregivers. For stroke patients, median NIHSS score was four. EQ-5D score was significantly worse in stroke, as compared to CHF and caregivers (0.52, 0.69 and 0.65, respectively). Mobility and usual activity domains were significantly affected in stroke and CHF patients as compared to caregivers; and self-care was more affected in stroke as compared with the other two groups. Conclusions Despite a mild neurological deficit, there was a significantly worse QOL perception in stroke as compared to CHF patients, mostly in their perception of self-care. PMID:21831270

  3. Differential aspects of stroke and congestive heart failure in quality of life reduction: a case series with three comparison groups

    Directory of Open Access Journals (Sweden)

    Cincura Carolina

    2011-08-01

    Full Text Available Abstract Background To assess QOL of patients with stroke in comparison to other groups (caregivers and CHF patients, to identify which items of QOL are more affected on each group and what is the functional profile of patients with stroke. Methods Consecutive stroke or congestive heart failure (CHF patients were evaluated and compared to their caregivers (caregivers. The NIH Stroke Scale (NIHSS and EuroQoL-5D (EQ-5D scale were applied. Results We evaluated 67 patients with stroke, 62 with CHF and 67 caregivers. For stroke patients, median NIHSS score was four. EQ-5D score was significantly worse in stroke, as compared to CHF and caregivers (0.52, 0.69 and 0.65, respectively. Mobility and usual activity domains were significantly affected in stroke and CHF patients as compared to caregivers; and self-care was more affected in stroke as compared with the other two groups. Conclusions Despite a mild neurological deficit, there was a significantly worse QOL perception in stroke as compared to CHF patients, mostly in their perception of self-care.

  4. Common Core State Standards for Mathematics: Teacher Self-Learning Series. Module 1: Introduction to the Common Core State Standards in Mathematics--The Need, the Development Process, the Common Languages, and the Structure

    Science.gov (United States)

    Louisiana Department of Education, 2013

    2013-01-01

    This module provides background information and presents the new terminology used in the Common Core State Standards for Mathematics (CCSSM). Educators should complete this module to understand the need for common standards, determine information about who developed the Standards, and learn the terminology and the coding used in the CCSSM. An…

  5. An unadjusted 25 group neutron cross section set for fast reactor core calculations from JENDL-2 library

    Energy Technology Data Exchange (ETDEWEB)

    Devan, K.; Gopalakrishnan, V.; Lee, S.M. [Nuclear Data Section Indira Ganhi Centre for Atomic Research, Tamilnadu (India)

    1994-12-31

    We have created a 25 group neutron cross section set (IGCJENDL) for nuclides of interest to LMFBRs from the Japanese Evaluated Nuclear Data Library - Version 2 (JENDL-2) in the format of French adjusted Cadarache Version 2 set (1969). The integral validation of IGCJENDL set was done by analyzing nine fast critical assemblies proposed by Cross Section Evaluation Working Group (CSEWG). The calculated integral parameters agreed reasonably well with the reported measured values. It is found that this set predicts the integral parameters, k-eff in particular, close to that predicted by adjusted CARNAVAL IV (French) or BNAB-78 (Russian) sets, for a 1200 MWe theoretical benchmark, representing a large power reactor.

  6. Common Core State Standards and Teacher Effectiveness. Q&A with Ross Wiener, Ph.D. REL Mid-Atlantic Teacher Effectiveness Webinar Series

    Science.gov (United States)

    Regional Educational Laboratory Mid-Atlantic, 2013

    2013-01-01

    In this REL Mid-Atlantic webinar, Dr. Ross Wiener, Vice President and Executive Director of the Education and Society Program, Aspen Institute, discussed strategies for integrating the Common Core State Standards (CCSS) into teacher effectiveness systems, including ways in which the CCSS can support professional growth and inform teacher…

  7. Core/shell-type nanorods of Tb{sup 3+}-doped LaPO{sub 4}, modified with amine groups, revealing reduced cytotoxicity

    Energy Technology Data Exchange (ETDEWEB)

    Runowski, Marcin [Adam Mickiewicz University, Department of Rare Earths, Faculty of Chemistry (Poland); Dąbrowska, Krystyna [Polish Academy of Sciences, Bacteriophage Laboratory, Institute of Immunology and Experimental Therapy (Poland); Grzyb, Tomasz [Adam Mickiewicz University, Department of Rare Earths, Faculty of Chemistry (Poland); Miernikiewicz, Paulina [Polish Academy of Sciences, Bacteriophage Laboratory, Institute of Immunology and Experimental Therapy (Poland); Lis, Stefan, E-mail: blis@amu.edu.pl [Adam Mickiewicz University, Department of Rare Earths, Faculty of Chemistry (Poland)

    2013-11-15

    A simple co-precipitation reaction between Ln{sup 3+} cations (Ln = lanthanide) and phosphate ions in the presence of polyethylene glycol (PEG), including post-treatment under hydrothermal conditions, leads to the formation of Tb{sup 3+}-doped LaPO{sub 4} crystalline nanorods. The nanoparticles obtained can be successfully coated with amorphous and porous silica, forming core/shell-type nanorods. Both products reveal intensive green luminescence under UV lamp irradiation. The surface of the core/shell-type product can also be modified with –NH{sub 2} groups via silylation procedure, using 3-aminopropyltriethoxysilane as a modifier. Powder X-ray diffraction, transmission electron microscopy, and scanning electron microscopy confirm the desired structure and needle-like shape of the products synthesized. Fourier transform infrared spectroscopy and specific surface area measurements by Brunauer–Emmett–Teller method reveal a successful surface modification with amine groups of the core/shell-type nanoparticles prepared. The nanomaterials synthesized exhibit green luminescence characteristic of Tb{sup 3+} ions, as solid powders and aqueous colloids, examined by spectrofluorometry. The in vitro cytotoxicity studies reveal different degree toxicity of the products. LaPO{sub 4}:Tb{sup 3+}@SiO{sub 2}@NH{sub 2} exhibits the smallest toxicity against B16F0 mouse melanoma cancer cells and human skin microvascular endothelial cell lines, in contrast to the most toxic LaPO{sub 4}:Tb{sup 3+}@SiO{sub 2}.Graphical Abstract.

  8. Phylogenetic diversity in the core group of Peziza inferred from ITS sequences and morphology

    DEFF Research Database (Denmark)

    Hansen, K.; Læssøe, Thomas; Pfister, D.H.

    2002-01-01

    ), shallowly cup- to disc-shaped apothecia (A) and large (up to 15 cm), deeply cup-shaped to expanded apothecia (B). The overall exciple structure (a stratified or non-stratified medullary layer) and to some degree spore surface relief, likewise support the groupings. Clade A contains taxa with smooth......, stratified or non-stratified medullary exciple (or thickness of the excipular layers), cell types in the outermost exciple and moniliform vs filiform paraphyses were not correlated with the subgroups supported by ITS analyses and appeared to be plastic. Therefore, P. cerea and P. micropus are placed...

  9. Performance of the TPSS Functional on Predicting Core Level Binding Energies of Main Group Elements Containing Molecules: A Good Choice for Molecules Adsorbed on Metal Surfaces.

    Science.gov (United States)

    Pueyo Bellafont, Noèlia; Viñes, Francesc; Illas, Francesc

    2016-01-12

    Here we explored the performance of Hartree-Fock (HF), Perdew-Burke-Ernzerhof (PBE), and Tao-Perdew-Staroverov-Scuseria (TPSS) functionals in predicting core level 1s binding energies (BEs) and BE shifts (ΔBEs) for a large set of 68 molecules containing a wide variety of functional groups for main group elements B → F and considering up to 185 core levels. A statistical analysis comparing with X-ray photoelectron spectroscopy (XPS) experiments shows that BEs estimations are very accurate, TPSS exhibiting the best performance. Considering ΔBEs, the three methods yield very similar and excellent results, with mean absolute deviations of ∼0.25 eV. When considering relativistic effects, BEs deviations drop approaching experimental values. So, the largest mean percentage deviation is of 0.25% only. Linear trends among experimental and estimated values have been found, gaining offsets with respect to ideality. By adding relativistic effects to offsets, HF and TPSS methods underestimate experimental values by solely 0.11 and 0.05 eV, respectively, well within XPS chemical precision. TPSS is posed as an excellent choice for the characterization, by XPS, of molecules on metal solid substrates, given its suitability in describing metal substrates bonds and atomic and/or molecular orbitals.

  10. Liquid-liquid reductive extraction in molten fluoride salt/liquid aluminium as a core of process for the An/Ln group separation

    Energy Technology Data Exchange (ETDEWEB)

    Conocar, O

    2007-06-15

    This report concerns a pyrochemical process based on liquid-liquid extraction in a molten fluoride/liquid aluminium system as a core process for actinide (An)/lanthanide (Ln) group separation, studied at CEA. The basic and demonstrative experiments have established the feasibility of the An/Ln group separation in the molten fluoride/liquid aluminium system (U, Pu, Np, Am, Cm traces from Nd, Ce, Eu, Sm, Eu, La - An/Ln separation factors over 1000 - An recovery yield over 98 % in one batch). The main experimental efforts must now be targeted on the recovery of actinides from the Al matrix. A thermodynamic and bibliographical survey has been done. It shows that back-extraction in a molten chloride melt could be a promising technique for this purpose.

  11. The Streptococcus milleri group--an unrecognized cause of disease in cystic fibrosis: a case series and literature review.

    Science.gov (United States)

    Parkins, Michael D; Sibley, Christopher D; Surette, Michael G; Rabin, Harvey R

    2008-05-01

    The "Streptococcus milleri" group (SMG) is increasingly recognized for their role in pyogenic infections including empyema and solid organ abscesses. However, SMG disease has rarely been identified in cystic fibrosis (CF). Inherent difficulties in both growing the organisms and distinguishing SMG from less virulent oropharyngeal viridans streptococci may have led to a decreased recognition of this as a CF pathogen. We report on six cases of SMG-related infection over a 4-year time-frame occurring within an adult CF clinic in Canada, and a further four cases identified through a literature review. SMG manifested disease as bronchopulmonary exacerbations in 7 of 10 patients, and 4 of 10 patients had extra-pulmonary dissemination of SMG infection. Noticeably, pulmonary exacerbations were frequently associated with atypically malodorous sputum. Furthermore, patients clinically responded to anti-microbial therapies with no anti-Pseudomonal activity. There was a consistent correlation of SMG disease and co-colonization with P. aeruginosa leading to speculation of polymicrobial interactions resulting in enhanced virulence. SMG deserves considerable attention as a potential pathogen within the airways of patients with CF.

  12. The EMCDDA/Pompidou Group treatment demand indicator protocol: a European core item set for treatment monitoring and reporting.

    Science.gov (United States)

    Simon, R; Donmall, M; Hartnoll, R; Kokkevi, A; Ouwehand, A W; Stauffacher, M; Vicente, J

    1999-12-01

    Over the last decades inside and outside of Europe, treatment-based data have been used in epidemiological research on drugs and drug abuse. They offer information on hidden populations and allow to follow socially stigmatised behaviour. As this type of research can be done on rather low budgets, there are long-term projects run in many countries. Experts from the national systems in several EU member states have been working together to develop a common standard on the basis of the Pompidou Group (PG) Definitive Protocol. The items and basic definitions of the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA)/PG Treatment Demand Indicator Protocol are described, which plays an important role in the process of harmonisation of data collection for the EMCDDA. Implementation strategies are described, and future steps are discussed.

  13. Supramolecular assembly and nanostructures of a series of luminol derivatives with aromatic/alkyl substituted groups in Langmuir-Blodgett films.

    Science.gov (United States)

    Jiao, Tifeng; Xing, Yuanyuan; Zhang, Qingrui; Zhang, Li; Liu, Minghua; Zhou, Jingxin; Gao, Faming

    2014-06-01

    A series of functional luminol derivatives with aromatic and alkyl substituted groups has been designed and synthesized from the reaction of the corresponding chloride precursors with luminol. These compounds can be spread on water surface to form stable Langmuir films at the air-water interface. It has been found that UV and IR spectra confirmed the characteristic aromatic segment, imide group, and aromatic/alkyl substituted groups. In addition, for the interfacial assembly process of compounds with alkyl substituted groups, there are obvious spectral changes for the alkyl chains. AFM results indicated that various different aggregated domains may be fabricated in the transferred LB films. For all cases, the substituted groups in molecular structures have an important effect in regulating the aggregation mode and spectral changes in organized molecular films. The present results showed that the modified luminol derivatives may have potential application in functional material fields such as ECL sensor, which may give some insight to study the relationship between the molecular structures and supramolecular aggregation of amphiphiles in organized molecular films.

  14. Multilevel Group Analysis on Bayesian in fMRI Time Series%Bayesian方法对fMRI数据的多层群组分析

    Institute of Scientific and Technical Information of China (English)

    周广田; 杨丰; 田晓英

    2016-01-01

    This paper suggests a method to process fMRI time series based on Bayesian inference for group analysis. The method uses multilevel divided by voxel, subject and group as pair comparison to reinforce posterior probability in group analysis from single subjects as priors. And also it combines classical statistics, i.e., t-test to obtain voxel activation at subject level as prior for Bayesian inference at group level. It effectively solves computation expensive and complexity. And it shows robust on Bayesian inference for group analysis.%本文采用Bayesian方法对fMRI时间序列数据对群组进行分析,群组按照体素、脑体、个体分为多层,比较个体的特征选取作为先验加强群组的后验计算,对个体的参数估计结合经典统计方法获得体素的激活区域作为群组Bayesian推理的先验,可以有效解决计算复杂性和计算成本,有效应用在群组分析中。

  15. Finding a Path to Entrustment in Undergraduate Medical Education: A Progress Report From the AAMC Core Entrustable Professional Activities for Entering Residency Entrustment Concept Group.

    Science.gov (United States)

    Brown, David R; Warren, Jamie B; Hyderi, Abbas; Drusin, Ronald E; Moeller, Jeremy; Rosenfeld, Melvin; Orlander, Philip R; Yingling, Sandra; Call, Stephanie; Terhune, Kyla; Bull, Janet; Englander, Robert; Wagner, Dianne P

    2017-06-01

    To better prepare graduating medical students to transition to the professional responsibilities of residency, 10 medical schools are participating in an Association of American Medical Colleges pilot to evaluate the feasibility of explicitly teaching and assessing 13 Core Entrustable Professional Activities for Entering Residency. The authors focused on operationalizing the concept of entrustment as part of this process. Starting in 2014, the Entrustment Concept Group, with representatives from each of the pilot schools, guided the development of the structures and processes necessary for formal entrustment decisions associated with students' increased responsibilities at the start of residency. Guiding principles developed by the group recommend that formal, summative entrustment decisions in undergraduate medical education be made by a trained group, be based on longitudinal performance assessments from multiple assessors, and incorporate day-to-day entrustment judgments by workplace supervisors. Key to entrustment decisions is evidence that students know their limits (discernment), can be relied on to follow through (conscientiousness), and are forthcoming despite potential personal costs (truthfulness), in addition to having the requisite knowledge and skills. The group constructed a developmental framework for discernment, conscientiousness, and truthfulness to pilot a model for transparent entrustment decision making. The pilot schools are studying a number of questions regarding the pathways to and decisions about entrustment. This work seeks to inform meaningful culture change in undergraduate medical education through a shared understanding of the assessment of trust and a shared trust in that assessment.

  16. Ab Initio Description of Open-Shell Nuclei: Merging No-Core Shell Model and In-Medium Similarity Renormalization Group

    CERN Document Server

    Gebrerufael, Eskendr; Hergert, Heiko; Roth, Robert

    2016-01-01

    We merge two successful ab initio nuclear-structure methods, the no-core shell model (NCSM) and the multi-reference in-medium similarity renormalization group (IM-SRG) to define a new many-body approach for the comprehensive description of ground and excited states of closed and open-shell nuclei. Building on the key advantages of the two methods---the decoupling of excitations at the many-body level in the IM-SRG and the access to arbitrary nuclei, eigenstates, and observables in the NCSM---their combination enables fully converged no-core calculations for an unprecedented range of nuclei and observables at moderate computational cost. We present applications in the carbon and oxygen isotopic chains, where conventional NCSM calculations are still feasible and provide an important benchmark. The efficiency and rapid convergence of the new approach make it ideally suited for ab initio studies of the complete spectroscopy of nuclei up into the medium-mass regime.

  17. Two-dimensional, Time-dependent, Multi-group, Multi-angle Radiation Hydrodynamics Test Simulation in the Core-Collapse Supernova Context

    CERN Document Server

    Livne, E; Walder, R; Lichtenstadt, I; Thompson, T A; Livne, Eli; Burrows, Adam; Walder, Rolf; Lichtenstadt, Itamar; Thompson, Todd A.

    2004-01-01

    We have developed a time-dependent, multi-energy-group, and multi-angle (S$_n$) Boltzmann transport scheme for radiation hydrodynamics simulations, in one and two spatial dimensions. The implicit transport is coupled to both 1D (spherically-symmetric) and 2D (axially-symmetric) versions of the explicit Newtonian hydrodynamics code VULCAN. The 2D variant, VULCAN/2D, can be operated in general structured or unstructured grids and though the code can address many problems in astrophysics it was constructed specifically to study the core-collapse supernova problem. Furthermore, VULCAN/2D can simulate the radiation/hydrodynamic evolution of differentially rotating bodies. We summarize the equations solved and methods incorporated into the algorithm and present results of a time-dependent 2D test calculation. A more complete description of the algorithm is postponed to another paper. We highlight a 2D test run that follows for 22 milliseconds the immediate post-bounce evolution of a collapsed core. We present the r...

  18. Ab Initio Description of Open-Shell Nuclei: Merging No-Core Shell Model and In-Medium Similarity Renormalization Group.

    Science.gov (United States)

    Gebrerufael, Eskendr; Vobig, Klaus; Hergert, Heiko; Roth, Robert

    2017-04-14

    We merge two successful ab initio nuclear-structure methods, the no-core shell model (NCSM) and the multireference in-medium similarity renormalization group (IM-SRG) to define a new many-body approach for the comprehensive description of ground and excited states of closed and open-shell nuclei. Building on the key advantages of the two methods-the decoupling of excitations at the many-body level in the IM-SRG and the access to arbitrary nuclei, eigenstates, and observables in the NCSM-their combination enables fully converged no-core calculations for an unprecedented range of nuclei and observables at moderate computational cost. We present applications in the carbon and oxygen isotopic chains, where conventional NCSM calculations are still feasible and provide an important benchmark. The efficiency and rapid convergence of the new approach make it ideally suited for ab initio studies of the complete spectroscopy of nuclei up into the medium-mass regime.

  19. Series Transmission Line Transformer

    Science.gov (United States)

    Buckles, Robert A.; Booth, Rex; Yen, Boris T.

    2004-06-29

    A series transmission line transformer is set forth which includes two or more of impedance matched sets of at least two transmissions lines such as shielded cables, connected in parallel at one end ans series at the other in a cascading fashion. The cables are wound about a magnetic core. The series transmission line transformer (STLT) which can provide for higher impedance ratios and bandwidths, which is scalable, and which is of simpler design and construction.

  20. Summation of series

    CERN Document Server

    Jolley, LB W

    2004-01-01

    Over 1,100 common series, all grouped for easy reference. Arranged by category, these series include arithmetical and geometrical progressions, powers and products of natural numbers, figurate and polygonal numbers, inverse natural numbers, exponential and logarithmic series, binomials, simple inverse products, factorials, trigonometrical and hyperbolic expansions, and additional series. 1961 edition.

  1. Polar Order and Symmetry Breaking at the Boundary between Bent-Core and Rodlike Molecular Forms: When 4-Cyanoresorcinol Meets the Carbosilane End Group.

    Science.gov (United States)

    Westphal, Eduard; Gallardo, Hugo; Caramori, Giovanni Finoto; Sebastián, Nerea; Tamba, Maria-Gabriela; Eremin, Alexey; Kawauchi, Susumu; Prehm, Marko; Tschierske, Carsten

    2016-06-01

    Two isomeric achiral bent-core liquid crystals involving a 4-cyanoresorcinol core and containing a carbosilane unit as nanosegregating segment were synthesized and were shown to form ferroelectric liquid-crystalline phases. Inversion of the direction of one of the COO groups in these molecules leads to a distinct distribution of the electrostatic potential along the surface of the molecule and to a strong change of the molecular dipole moments. Thus, a distinct degree of segregation of the carbosilane units and consequent modification of the phase structure and coherence length of polar order result. For the compound with larger dipole moment (CN1) segregation of the carbosilane units is suppressed, and this compound forms paraelectric SmA and SmC phases; polar order is only achieved after transition to a new LC phase, namely, the ferroelectric leaning phase (SmCLs PS ) with the unique feature that tilt direction and polar direction coincide. The isomeric compound CN2 with a smaller dipole moment forms separate layers of the carbosilane groups and shows a randomized polar SmA phase (SmAPAR ) and ferroelectric polydomain SmCs PS phases with orthogonal combination of tilt and polar direction and much higher polarizations. Thus, surprisingly, the compound with the smaller molecular dipole moment shows increased polar order in the LC phases. Besides ferroelectricity, mirror-symmetry breaking with formation of a conglomerate of macroscopic chiral domains was observed in one of the SmC phases of CN1. These investigations contribute to the general understanding of the development of polar order and chirality in soft matter.

  2. Environmental health research recommendations from the Inter-Environmental Health Sciences Core Center Working Group on unconventional natural gas drilling operations.

    Science.gov (United States)

    Penning, Trevor M; Breysse, Patrick N; Gray, Kathleen; Howarth, Marilyn; Yan, Beizhan

    2014-11-01

    Unconventional natural gas drilling operations (UNGDO) (which include hydraulic fracturing and horizontal drilling) supply an energy source that is potentially cleaner than liquid or solid fossil fuels and may provide a route to energy independence. However, significant concerns have arisen due to the lack of research on the public health impact of UNGDO. Environmental Health Sciences Core Centers (EHSCCs), funded by the National Institute of Environmental Health Sciences (NIEHS), formed a working group to review the literature on the potential public health impact of UNGDO and to make recommendations for needed research. The Inter-EHSCC Working Group concluded that a potential for water and air pollution exists that might endanger public health, and that the social fabric of communities could be impacted by the rapid emergence of drilling operations. The working group recommends research to inform how potential risks could be mitigated. Research on exposure and health outcomes related to UNGDO is urgently needed, and community engagement is essential in the design of such studies.

  3. Core biopsy needle versus standard aspiration needle for endoscopic ultrasound-guided sampling of solid pancreatic masses: a randomized parallel-group study.

    Science.gov (United States)

    Lee, Yun Nah; Moon, Jong Ho; Kim, Hee Kyung; Choi, Hyun Jong; Choi, Moon Han; Kim, Dong Choon; Lee, Tae Hoon; Cha, Sang-Woo; Cho, Young Deok; Park, Sang-Heum

    2014-12-01

    An endoscopic ultrasound (EUS)-guided fine needle biopsy (EUS-FNB) device using a core biopsy needle was developed to improve diagnostic accuracy by simultaneously obtaining cytological aspirates and histological core samples. We prospectively compared the diagnostic accuracy of EUS-FNB with standard EUS-guided fine needle aspiration (EUS-FNA) in patients with solid pancreatic masses. Between January 2012 and May 2013, consecutive patients with solid pancreatic masses were prospectively enrolled and randomized to undergo EUS-FNB using a core biopsy needle or EUS-FNA using a standard aspiration needle at a single tertiary center. The specimen was analyzed by onsite cytology, Papanicolaou-stain cytology, and histology. The main outcome measure was diagnostic accuracy for malignancy. The secondary outcome measures were: the median number of passes required to establish a diagnosis, the proportion of patients in whom the diagnosis was established with each pass, and complication rates. The overall accuracy of combining onsite cytology with Papanicolaou-stain cytology and histology was not significantly different for the FNB (n = 58) and FNA (n = 58) groups (98.3 % [95 %CI 94.9 % - 100 %] vs. 94.8 % [95 %CI 91.9 % - 100 %]; P = 0.671). Compared with FNA, FNB required a significantly lower median number of needle passes to establish a diagnosis (1.0 vs. 2.0; P < 0.001). On subgroup analysis of 111 patients with malignant lesions, the proportion of patients in whom malignancy was diagnosed on the first pass was significantly greater in the FNB group (72.7 % vs. 37.5 %; P < 0.001). The overall accuracy of FNB and FNA in patients with solid pancreatic masses was comparable; however, fewer passes were required to establish the diagnosis of malignancy using FNB.This study was registered on the UMIN Clinical Trial Registry (UMIN000014057). © Georg Thieme Verlag KG Stuttgart · New York.

  4. Determinants of performance of supplemental immunization activities for polio eradication in Uttar Pradesh, India: social mobilization activities of the Social mobilization Network (SM Net and Core Group Polio Project (CGPP

    Directory of Open Access Journals (Sweden)

    Weiss William M

    2013-01-01

    Full Text Available Abstract Background The primary strategy to interrupt transmission of wild poliovirus in India is to improve supplemental immunization activities (SIAs and routine immunization coverage in priority districts. The CORE Group, part of the Social Mobilization Network (SM Net, has been successful in improving SIA coverage in high-risk areas of Uttar Pradesh (UP. The SM Net works through community level mobilisers (from the CORE Group and UNICEF and covers more than 2 million children under the age of five. In this paper, we examine the reasons the CORE Group had been successful through exploration of which social mobilization activities of the CORE Group predicted better performance of SIAs. Methods We carried out a secondary data analysis of routine monitoring information collected by the CORE Group and the Government of India for SIAs. These data included information about vaccination outcomes of SIAs in CORE Group areas and non-CORE Group areas within the districts where the CORE Group operates, along with information about the number of various social mobilization activities carried out for each SIA. We employed Generalized Linear Latent and Mixed Model (GLLAMM statistical analysis methods to identify which social mobilization activities predicted SIA performance, and to account for the intra-class correlation (ICC between multiple observations within the same geographic areas over time. Results The number of mosque announcements carried out was the most consistent determinant of improved SIA performance across various performance measures. The number of Bullawa Tollies carried out also appeared to be an important determinant of improved SIA performance. The number of times other social mobilization activities were carried out did not appear to determine better SIA performance. Conclusions Social mobilization activities can improve the performance of mass vaccination campaigns. In the CORE Group areas, the number of mosque announcements and

  5. Discotic liquid crystalline tris(hexahexyloxytriphenylene)triazines with separate columns of triphenylene and triazine cores

    NARCIS (Netherlands)

    Umesh, C.P.; Gangarapu, S.; Marcelis, A.T.M.; Zuilhof, H.

    2014-01-01

    A series of novel discotic liquid crystal compounds containing three pendent triphenylenes connected to a triazine core via spacers of different length that were linked via a triazole group as obtained from an azide–alkyne click reaction was investigated. All compounds of the series exhibit

  6. 网站群系统核心功能研究%Research on the Core Functions of the Website Group System

    Institute of Scientific and Technical Information of China (English)

    马亮

    2015-01-01

    网站群系统是现代建设网站的首先技术,尤其是在同一组织机构中建设多个网站。采用网站群系统建设网站,可以把众多网站置于一套站群系统之下,由于各网站使用同一数据库及系统,网站之间不会形成信息孤岛,利于信息的搜索和使用,另外由于站群系统多由专业的软件公司开发,公司的专业能力保证了站群系统的安全性。笔者在单位负责全校网站建设,使用过几个站群系统,使用中也对其中一个问题产生了兴趣,网站群系统的核心功能到底是什么?今天这篇论文就此展开研究。%Website group system is the first technology of the modern construction site, especially in the same organization in the construction of multiple sites. The website group system construction site, you can put many site under a standing group of sys-tem under, due to the site using the same database and system, between the website does not form information isolated island, to search and use of information, also due to the station group system multi developed by professional software company, compa-ny's professional ability ensures the system security station. I in the unit responsible for the construction of the whole school website, use a few station group system, use of one of the questions generated interest, the core function of the website group system in the end is what? Today, this thesis is a research on this thesis.

  7. The t-core of an s-core

    OpenAIRE

    Fayers, Matthew

    2010-01-01

    We consider the $t$-core of an $s$-core partition, when $s$ and $t$ are coprime positive integers. Olsson has shown that the $t$-core of an $s$-core is again an $s$-core, and we examine certain actions of the affine symmetric group on $s$-cores which preserve the $t$-core of an $s$-core. Along the way, we give a new proof of Olsson's result. We also give a new proof of a result of Vandehey, showing that there is a simultaneous $s$- and $t$-core which contains all others.

  8. The t-core of an s-core

    OpenAIRE

    Fayers, Matthew

    2010-01-01

    We consider the $t$-core of an $s$-core partition, when $s$ and $t$ are coprime positive integers. Olsson has shown that the $t$-core of an $s$-core is again an $s$-core, and we examine certain actions of the affine symmetric group on $s$-cores which preserve the $t$-core of an $s$-core. Along the way, we give a new proof of Olsson's result. We also give a new proof of a result of Vandehey, showing that there is a simultaneous $s$- and $t$-core which contains all others.

  9. Conversation therapy with people with aphasia and conversation partners using video feedback: a group and case series investigation of changes in interaction.

    Directory of Open Access Journals (Sweden)

    Wendy Best

    2016-11-01

    Full Text Available Conversation therapies employing video for feedback and to facilitate outcome measurement are increasingly used with people with post-stroke aphasia and their conversation partners; however the evidence base for change in everyday interaction remains limited. We investigated the effect of Better Conversations with Aphasia, an intervention that is freely available online (https:// extend.ucl.ac.uk/. Eight people with chronic agrammatic aphasia, and their regular conversation partners participated in the tailored 8 week program involving significant video feedback. We explored changes in (i conversation facilitators (such as multi-modal turns by people with aphasia and (ii conversation barriers (such as use of test questions by conversation partners. The outcome of intervention was evaluated directly by measuring change in video-recorded everyday conversations. The study employed a pre-post design with multiple 5 minute samples of conversation before and after intervention, scored by trained raters blind to the point of data collection. Group level analysis showed no significant increase in conversation facilitators. There was, however, a significant reduction in the number of conversation barriers. The case series data revealed variability in conversation behaviors across occasions for the same dyad and between different dyads. Specifically, post-intervention there was a significant increase in facilitator behaviors for two dyads, a decrease for one and no significant change for five dyads. There was a significant decrease in barrier behaviors for five dyads and no significant change for three dyads. The reduction in barrier behaviors was considerable; on average change from over 8 to fewer than 3 barrier behaviors in 5 minutes conversation. The pre-post design has the limitation of no comparison group. However, change occurs in targeted conversational behaviors and in people with chronic aphasia and their partners. The findings suggest change

  10. Search for a meteoritic component in drill cores from the Bosumtwi impact structure, Ghana: Platinum group element contents and osmium isotopic characteristics

    Science.gov (United States)

    McDonald, Iain; Peucker-Ehrenbrink, Bernhard; Coney, Louise; Ferrière, Ludovic; Reimold, Wolf Uwe; Koeberl, Christian

    An attempt was made to detect a meteoritic component in both crater-fill (fallback) impact breccias and fallout suevites (outside the crater rim) at the Bosumtwi impact structure in Ghana. Thus far, the only clear indication for an extraterrestrial component related to this structure has been the discovery of a meteoritic signature in Ivory Coast tektites, which formed during the Bosumtwi impact event. Earlier work at Bosumtwi indicated unusually high levels of elements that are commonly used for the identification of meteoritic contamination (i.e., siderophile elements, including the platinum group elements [PGE]) in both target rocks and impact breccias from surface exposures around the crater structure, which does not allow unambiguous verification of an extraterrestrial signature. The present work, involving PGE abundance determinations and Os isotope measurements on drill core samples from inside and outside the crater rim, arrives at the same conclusion. Despite the potential of the Os isotope system to detect even small amounts of extraterrestrial contribution, the wide range in PGE concentrations and Os isotope composition observed in the target rocks makes the interpretation of unradiogenic, high-concentration samples as an impact signature ambiguous.

  11. Large Core Code Evaluation Working Group Benchmark Problem Four: neutronics and burnup analysis of a large heterogeneous fast reactor. Part 1. Analysis of benchmark results. [LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Cowan, C.L.; Protsik, R.; Lewellen, J.W. (eds.)

    1984-01-01

    The Large Core Code Evaluation Working Group Benchmark Problem Four was specified to provide a stringent test of the current methods which are used in the nuclear design and analyses process. The benchmark specifications provided a base for performing detailed burnup calculations over the first two irradiation cycles for a large heterogeneous fast reactor. Particular emphasis was placed on the techniques for modeling the three-dimensional benchmark geometry, and sensitivity studies were carried out to determine the performance parameter sensitivities to changes in the neutronics and burnup specifications. The results of the Benchmark Four calculations indicated that a linked RZ-XY (Hex) two-dimensional representation of the benchmark model geometry can be used to predict mass balance data, power distributions, regionwise fuel exposure data and burnup reactivities with good accuracy when compared with the results of direct three-dimensional computations. Most of the small differences in the results of the benchmark analyses by the different participants were attributed to ambiguities in carrying out the regionwise flux renormalization calculations throughout the burnup step.

  12. A DFT and Semiempirical Model-Based Study of Opioid Receptor Affinity and Selectivity in a Group of Molecules with a Morphine Structural Core

    Directory of Open Access Journals (Sweden)

    Tamara Bruna-Larenas

    2012-01-01

    Full Text Available We report the results of a search for model-based relationships between mu, delta, and kappa opioid receptor binding affinity and molecular structure for a group of molecules having in common a morphine structural core. The wave functions and local reactivity indices were obtained at the ZINDO/1 and B3LYP/6-31 levels of theory for comparison. New developments in the expression for the drug-receptor interaction energy expression allowed several local atomic reactivity indices to be included, such as local electronic chemical potential, local hardness, and local electrophilicity. These indices, together with a new proposal for the ordering of the independent variables, were incorporated in the statistical study. We found and discussed several statistically significant relationships for mu, delta, and kappa opioid receptor binding affinity at both levels of theory. Some of the new local reactivity indices incorporated in the theory appear in several equations for the first time in the history of model-based equations. Interaction pharmacophores were generated for mu, delta, and kappa receptors. We discuss possible differences regulating binding and selectivity in opioid receptor subtypes. This study, contrarily to the statistically backed ones, is able to provide a microscopic insight of the mechanisms involved in the binding process.

  13. Delayed presentation of fracture of lateral condyle of humerus in pediatric age group treated by ORIF and ulnar peg grafting: A case series

    Directory of Open Access Journals (Sweden)

    Nishikant Kumar

    2015-01-01

    Full Text Available Background: Fractures of lateral condyle of humerus in pediatric age group, the most common being distal humerus epiphyseal injury, are commonly associated with delayed presentation to terminal health care providers. Reasons accounted might be at every level, right from the patient to the physician. In the backdrop of existing disputed treatment strategy operative v/s non-operative treatment of fractures having more than 3-week duration of injury, same were treated by open reduction and k wire fixation using ulnar peg graft. Final functional result was evaluated with longest follow up of over 1 year. Materials and Methods: Twenty children having fracture of lateral condyle of humerus with duration of trauma more than 3 week were included in the prospective study. Age ranged from 5 years to 15 years. Average age was 8 years. Among the 20 patients, 8 were male and 12 were female. Average time of presentation was after 5 weeks of injury. Seven patients had milch type 1 injury and 13 patients had milch type II injury. All patients were treated by open reduction and internal fixation using k wires and ulnar peg graft. The follow-up period was over 1 year. Result: Results were evaluated using radiograph, and functional results were evaluated using the Liverpool elbow scoring system. In the present series, all fractures united with 92% excellent, 5% good, and 3% poor results. Poor results were associated with greater displacement of fracture, prior repeated attempts of close reduction, and history of massage. Conclusion: Being an epiphyseal injury and a common occurrence, fracture of lateral condyle of humerus in pediatric age group are commonly maltreated, with error contributed right from parents to even physician. Common reasons of delayed presentation are ignorance on parents′ side, malpractice by some bone-setters, poorly done radiograph, inaccurate radiographic interpretation by the physician, and poor selection of treatment methods.

  14. Proteomics Core

    Data.gov (United States)

    Federal Laboratory Consortium — Proteomics Core is the central resource for mass spectrometry based proteomics within the NHLBI. The Core staff help collaborators design proteomics experiments in a...

  15. Proteomics Core

    Data.gov (United States)

    Federal Laboratory Consortium — Proteomics Core is the central resource for mass spectrometry based proteomics within the NHLBI. The Core staff help collaborators design proteomics experiments in...

  16. Fourier series

    CERN Document Server

    Tolstov, Georgi P

    1962-01-01

    Richard A. Silverman's series of translations of outstanding Russian textbooks and monographs is well-known to people in the fields of mathematics, physics, and engineering. The present book is another excellent text from this series, a valuable addition to the English-language literature on Fourier series.This edition is organized into nine well-defined chapters: Trigonometric Fourier Series, Orthogonal Systems, Convergence of Trigonometric Fourier Series, Trigonometric Series with Decreasing Coefficients, Operations on Fourier Series, Summation of Trigonometric Fourier Series, Double Fourie

  17. A、B色系IPS E.max LT底层材料色度值和相对透明率测定%Relative translucency and chromatic value test of A and B color series IPS E.max LT core materials

    Institute of Scientific and Technical Information of China (English)

    邵龙泉; 孙挺; 伊元夫; 邓斌; 温宁; 刘琦

    2011-01-01

    目的:测定A、B色系IPS E.max LT底层材料的CIE-1976-L* a* b*色度值和相对透明率.方法:制作直径为13mm、厚度为0.3 mm和0.5 mm的A、B色系盘状IPS E.max LT试件,色号包括A1、A2、A3、A3.5、A4、B1、B2、B3、B4,共计18组(n=5),应用CM-5分光测色计测试试件在标准黑、白背景下的表面光反射率Y值,记录Yb、Yw平均值,计算相对透明率(Yb/Yw);测试A、B色系瓷锭的色度值.结果:同一色系内,各组瓷锭明度值的总体均数不相等,组间差异具有显著性(P<0.01).从A1到A4、B1到B4,明度值均逐渐减低.相同厚度、相同色系的试件组间相对透明率差异无显著性(P>0.05),相对透明率数值分布范围为0.330 9~0.5875.相同色号、不同厚度的2组试件组间差异均具有显著性,0.3 mm组底层材料的相对透明率小于0.5 mm组(P<0.05).结论:厚度是A、B色系IPS E.max LT底层材料相对透明率的重要相关因素.%Objective: To study the relative translucency and chromatic value of IPS E. Max A and B color series core materials. Methods: Cylindrical core materials dentine porcelain specimen disks with diameter of 13.0 mm, thickness of 0.3 mm or 0.5 mm were respectively made(ra=5). The reflectivity value(Yb and Yw) of all samples was determined with CM-5 chromatism instrument, and the relative translucency(Yb/Yw) was calculated. The chromatic value of ceramic ingots provided by the manufacturer was measuredtoo. Results: L * of ceramic ingots was significantly different among specimen groups of A or B color series( P <0.01). From Al to A4 and from B1 to B4, L * declined. There was no significant different among specimen groups which had same thickness and belonged to same color series. The range of relative translucency was between 0. 330 9 and 0.587 5. Significant difference was found between specimen groups which had different thickness and same color number( P < 0.05 ). Conclusion: Thickness is an important factor of translucency for

  18. A Discussion of the Various Groups of Readers in the Fairytale Project, with a Detailed Description of the "Core-Groups" in Denmark and Turkey. Fairytale: An Interdisciplinary Turco-Danish Study of the Collective v. the Individual Nature of the Response to Literature. Report No. 10. Revised.

    Science.gov (United States)

    Dollerup, Cay; And Others

    Prepared as part of the interdisciplinary Turko-Danish Fairytale Project, this paper contains descriptions of the core group of readers (600 18-year-old students) and the special groups of readers (each composed of approximately 50 subjects) who participated in the investigation of the collective versus the individual nature of the reader response…

  19. 多群粒子输运问题在多核集群系统上的混合并行计算%Hybrid Parallel Computation of Multi-Group Particle transport Equations on Multi-Core Cluster Systems

    Institute of Scientific and Technical Information of China (English)

    迟利华; 刘杰; 龚春叶; 徐涵; 蒋杰; 胡庆丰

    2009-01-01

    The parallel performance of solving the multi-group particle transport equations on the unstructure meshes is analyzed Adapting to the characteristics of multi-core cluster systems, this paper desgins a MPI/OpenMP hybrid parallel code. For the meshes, the space domain decomposition is adopted, and MPI between the computations of multi-core CPU nodes is used. When each MPI process begin to compute the variables of the energy groups, several OpenMP threads will be forked, and the threads start to compute simultaneously in the same mutli-core CPU node. Using the MPI/OpenMP hybrid parallel code, we solve a 2D mutli-group particle transport equation on a cluster with mutli-core CPU nodes, and the results show that the code has good scalability and can be scaled to 1024 CPU cores.%本文分析了非结构网格多群粒子输运Sn方程求解的并行性,拟合多核机群系统的特点,设计了MPI/OpenMP混合程序,针对空间网格点采用区域分解划分,计算结点间基于消息传递MPI编程,每个MPI计算进程在计算过程中碰到关于能群的计算,就生成多个OpenMP线程,计算结点内针对能群进行多线程并行计算.数值测试结果表明,非结构网格上的粒子输运问题的混合并行计算能较好地匹配多核机群系统的硬件结构,具有良好的可扩展性,可以扩展到1 024个CPU核.

  20. Ice cores

    DEFF Research Database (Denmark)

    Svensson, Anders

    2014-01-01

    Ice cores from Antarctica, from Greenland, and from a number of smaller glaciers around the world yield a wealth of information on past climates and environments. Ice cores offer unique records on past temperatures, atmospheric composition (including greenhouse gases), volcanism, solar activity......, dustiness, and biomass burning, among others. In Antarctica, ice cores extend back more than 800,000 years before present (Jouzel et al. 2007), whereas. Greenland ice cores cover the last 130,000 years...

  1. Ice cores

    DEFF Research Database (Denmark)

    Svensson, Anders

    2014-01-01

    Ice cores from Antarctica, from Greenland, and from a number of smaller glaciers around the world yield a wealth of information on past climates and environments. Ice cores offer unique records on past temperatures, atmospheric composition (including greenhouse gases), volcanism, solar activity......, dustiness, and biomass burning, among others. In Antarctica, ice cores extend back more than 800,000 years before present (Jouzel et al. 2007), whereas. Greenland ice cores cover the last 130,000 years...

  2. 用重整化群理论研究硬核Asakura-Oosawa流体的相平衡%Study on the Phase Equilibria of Hard Core Asakura-Oosawa Fluids with Renormalization-group Theory

    Institute of Scientific and Technical Information of China (English)

    付东

    2004-01-01

    An analytical equation of state (EOS) for hard core Asakura-Oosawa (AO) fluid is established by combining the AO potential, the first-order perturbation theory and the radial distribution function (RDF) for the hard sphere fluid. The phase equilibria are studied by using the renormalization-group (RG) theory. The obtained results agree well with the simulation data. Investigation shows that the attractive range parameter plays an important role in the phase equilibria for AO fluid.

  3. Grouped frequent sequential patterns derived from terrestrial image time series to monitor landslide behaviour - Application to the dynamics of the Sanières/Roche Plombée rockslide.

    Science.gov (United States)

    Péricault, Youen; Pothier, Catherine; Méger, Nicolas; Trouvé, Emmanuel; Vernier, Flavien; Rigotti, Christophe; Malet, Jean-Philippe

    2016-04-01

    Image time series acquired with remote sensing methods based on optical terrestrial photogrammetry have great potential for understanding and monitoring the Earth surface dynamics at local scale, and are particularly interesting for landslide monitoring. Image correlation techniques can be applied to calculate the displacement fields, in either the image geometry or the terrain geometry if orthorectification procedures are applied. The resulting products are times series of displacement vectors for each epoch in which knowledge extraction techniques can be applied to discover relevant movement patterns in space and time. We used an unsupervised method (Grouped Frequent Sequential patterns / GFS-patterns) based on the mining of the displacement field. The method was originally developed for the analysis of time series of satellite images. It involves the extraction of trends / sub-trends affecting each pixel covering at least a minimum surface area and sufficiently connected to each other. The results of the mining are presented in spatio-temporal location maps (STL-map) of each GFS-pattern. In these maps, the spatial information is given by the pixel locations and the time information is displayed using a color ramp. The method is tested on a time series of 36 optical terrestrial images of the Sanières/Roche Plombée rockslide (South East French Alps) from 28 of July to 1 September 2014. From this series 35 2D displacement fields were calculated for epochs of three days, and the time series of vector magnitude and direction were analysed with GFS-patterns / STL-map. The method allowed identifying several patterns corresponding to different kinematical behaviour of the rockslide (long-term creep at the top of the slope, surficial movement of the debris at the base of the slope). The unsupervised knowledge extraction method GFS-pattern / STL-map, originally developed to analyse time series of satellite images showed in this study real possibilities of use for

  4. Time Series

    OpenAIRE

    Gil-Alana, L.A.; Moreno, A; Pérez-de-Gracia, F. (Fernando)

    2011-01-01

    The last 20 years have witnessed a considerable increase in the use of time series techniques in econometrics. The articles in this important set have been chosen to illustrate the main themes in time series work as it relates to econometrics. The editor has written a new concise introduction to accompany the articles. Sections covered include: Ad Hoc Forecasting Procedures, ARIMA Modelling, Structural Time Series Models, Unit Roots, Detrending and Non-stationarity, Seasonality, Seasonal Adju...

  5. Synthesis, characterization, and antitumor activity of a series of novel cisplatin analogs with cis-1,4-diaminocyclohexane as nonleaving amine group.

    Science.gov (United States)

    Shamsuddin, S; Takahashi, I; Siddik, Z H; Khokhar, A R

    1996-03-01

    A series of novel platinum(II) complexes of the type PtII(cis-1,4-DACH)X (where cis-1,4-DACH = cis-1,4-diaminocyclohexane and X = dichloro, sulfato, oxalato, malonato, methylmalonato, tartronato, or 1,1-cyclobutanedicarboxylato [CBDCA) ligand and novel platinum(IV) complexes of the types PtIV(cis-1,4-DACH)trans(Y)2Cl2 (where Y = chloro, hydroxo, acetato, propionato, or butyrato ligand) and PtIV(cis-1,4-DACH)trans(Cl)2(X) (where X = oxalato or CBDCA ligand) were synthesized and characterized by elemental analysis, infrared, and 195Pt NMR spectroscopic techniques. Platinum complexes had good in vitro cytotoxic activity against murine leukemia L1210/0 (IC50 = 0.0032-1.60 microM) and human ovarian A2780 (IC50 = 0.045-0.430 microM) cell lines.

  6. Development of Few Group Cross Section Calculation Model for Core Nuclear Design Code CYCAS%堆芯核设计程序CYCAS少群截面模型开发

    Institute of Scientific and Technical Information of China (English)

    杨伟焱; 汤春桃; 毕光文; 杨波

    2016-01-01

    少群截面模型为堆芯三维扩散计算提供实时的节块均匀少群截面,是堆芯计算程序的关键模型之一.CYCAS程序是上海核工程研究设计院最新开发的堆芯三维核设计程序.本文在详细解析影响节块截面的各种因素的基础上,提出应用于CYCAS程序的少群截面的模型.该模型采用能谱修正方法处理由于能谱变化所引入的二次效应,采用微观燃耗修正方法处理燃耗历史效应.单组件和A P1000核电厂的数值验证计算表明,该模型具有很高的计算精度.%The few group cross section calculation model generates node homogeneous few group cross section for core 3D diffusion calculation ,w hich is one of the key models of core calculation code .CYCAS is the new core 3D nuclear design code developed by Shanghai Nuclear Engineering Research & Design Institute (SNERDI) .A new model based on detail analysis of the factors affecting node cross section was developed for CYCAS .In the model ,the energy spectrum correction method was used to process the second order effect introduced by energy spectrum change , and the micro-depletion correction method was utilized to treat depletion history effect .The numerical results of unit assembly and AP1000 core validate the high accuracy of the new model within CYCAS .

  7. Transformer core

    NARCIS (Netherlands)

    Mehendale, A.; Hagedoorn, Wouter; Lötters, Joost Conrad

    2010-01-01

    A transformer core includes a stack of a plurality of planar core plates of a magnetically permeable material, which plates each consist of a first and a second sub-part that together enclose at least one opening. The sub-parts can be fitted together via contact faces that are located on either side

  8. Transformer core

    NARCIS (Netherlands)

    Mehendale, A.; Hagedoorn, Wouter; Lötters, Joost Conrad

    2008-01-01

    A transformer core includes a stack of a plurality of planar core plates of a magnetically permeable material, which plates each consist of a first and a second sub-part that together enclose at least one opening. The sub-parts can be fitted together via contact faces that are located on either side

  9. Schumpeter's core works revisited

    DEFF Research Database (Denmark)

    Andersen, Esben Sloth

    2012-01-01

    This paper organises Schumpeter’s core books in three groups: the programmatic duology,the evolutionaryeconomic duology,and the socioeconomic synthesis. By analysing these groups and their interconnections from the viewpoint of modern evolutionaryeconomics,the paper summarises resolved problems...

  10. The Anatomical Society core regional anatomy syllabus for undergraduate medicine.

    Science.gov (United States)

    Smith, C F; Finn, G M; Stewart, J; Atkinson, M A; Davies, D C; Dyball, R; Morris, J; Ockleford, C; Parkin, I; Standring, S; Whiten, S; Wilton, J; McHanwell, S

    2016-01-01

    The Anatomical Society's core syllabus for anatomy (2003 and later refined in 2007) set out a series of learning outcomes that an individual medical student should achieve on graduation. The core syllabus, with 182 learning outcomes grouped in body regions, referenced in the General Medical Council's Teaching Tomorrow's Doctors, was open to criticism on the grounds that the learning outcomes were generated by a relatively small group of anatomists, albeit some of whom were clinically qualified. We have therefore used a modified Delphi technique to seek a wider consensus. A Delphi panel was constructed involving 'experts' (n = 39). The revised core syllabus of 156 learning outcomes presented here is applicable to all medical programmes and may be used by curriculum planners, teachers and students alike in addressing the perennial question: 'What do I need to know ?'

  11. Cancer in human immunodeficiency virus-infected children : A case series from the Children's Cancer Group and the National Cancer Institute

    NARCIS (Netherlands)

    Granovsky, MO; Mueller, BU; Nicholson, HS; Rosenberg, PS; Rabkin, CS

    1998-01-01

    Purpose: To describe the spectrum of malignancies in human immunodeficiency virus (HIV)-infected children and the clinical outcome of patients with these tumors. Methods: We retrospectively surveyed the Children's Cancer Group (CCG) and the National Cancer institute (NCI) for cases of cancer that oc

  12. A Comparison of Four Linear Equating Methods for the Common-Item Nonequivalent Groups Design Using Simulation Methods. ACT Research Report Series, 2013 (2)

    Science.gov (United States)

    Topczewski, Anna; Cui, Zhongmin; Woodruff, David; Chen, Hanwei; Fang, Yu

    2013-01-01

    This paper investigates four methods of linear equating under the common item nonequivalent groups design. Three of the methods are well known: Tucker, Angoff-Levine, and Congeneric-Levine. A fourth method is presented as a variant of the Congeneric-Levine method. Using simulation data generated from the three-parameter logistic IRT model we…

  13. Paying the Price of Desolvation in Solvent-Exposed Protein Pockets: Impact of Distal Solubilizing Groups on Affinity and Binding Thermodynamics in a Series of Thermolysin Inhibitors.

    Science.gov (United States)

    Cramer, Jonathan; Krimmer, Stefan G; Heine, Andreas; Klebe, Gerhard

    2017-07-13

    In lead optimization, open, solvent-exposed protein pockets are often disregarded as prospective binding sites. Because of bulk-solvent proximity, researchers are instead enticed to attach charged polar groups at inhibitor scaffolds to improve solubility and pharmacokinetic properties. It is rarely considered that solvent effects from water reorganization in the first hydration shell of protein-ligand complexes can have a significant impact on binding. We investigate the thermodynamic fingerprint of thermolysin inhibitors featuring terminal charged ammonium groups that are gradually pulled from a distal, solvent-exposed position into the flat, bowl-shaped S2' pocket. Even for the most remote attachment, costs for partial desolvation of the polar group next to the protein-solvent interface are difficult to compensate by interactions with the protein or surrounding water molecules. Through direct comparison with hydrophobic analogues, a significant 180-fold affinity loss was recorded, which questions popular strategies to attach polar ligand-solubilizing groups at the exposed terminus of substituents accommodated in flat open pockets.

  14. Cancer in human immunodeficiency virus-infected children : A case series from the Children's Cancer Group and the National Cancer Institute

    NARCIS (Netherlands)

    Granovsky, MO; Mueller, BU; Nicholson, HS; Rosenberg, PS; Rabkin, CS

    1998-01-01

    Purpose: To describe the spectrum of malignancies in human immunodeficiency virus (HIV)-infected children and the clinical outcome of patients with these tumors. Methods: We retrospectively surveyed the Children's Cancer Group (CCG) and the National Cancer institute (NCI) for cases of cancer that oc

  15. Cancer in human immunodeficiency virus-infected children : A case series from the Children's Cancer Group and the National Cancer Institute

    NARCIS (Netherlands)

    Granovsky, MO; Mueller, BU; Nicholson, HS; Rosenberg, PS; Rabkin, CS

    Purpose: To describe the spectrum of malignancies in human immunodeficiency virus (HIV)-infected children and the clinical outcome of patients with these tumors. Methods: We retrospectively surveyed the Children's Cancer Group (CCG) and the National Cancer institute (NCI) for cases of cancer that

  16. Report of the Expert Group Meeting on Population and Development Planning (Bangkok, 5-11 July 1977). Asian Population Studies Series No. 39.

    Science.gov (United States)

    United Nations Economic and Social Commission for Asia and the Pacific, Bangkok (Thailand).

    A group of experts on population and development planning met in Bangkok, Thailand in July, 1977. The meeting was organized by the United Nations Economic and Social Commission for Asia and the Pacific. This report is the result of background papers used at the conference, reactions to the papers, and further writing. The purpose of the meeting…

  17. A compact and realistic cerebral cortical layout derived from prewhitened resting-state fMRI time series: Cherniak's adjacency rule, size law, and metamodule grouping upheld.

    Science.gov (United States)

    Lewis, Scott M; Christova, Peka; Jerde, Trenton A; Georgopoulos, Apostolos P

    2012-01-01

    We used hierarchical tree clustering to derive a functional organizational chart of 52 human cortical areas (26 per hemisphere) from zero-lag correlations calculated between single-voxel, prewhitened, resting-state BOLD fMRI time series in 18 subjects. No special "resting-state networks" were identified. There were four major features in the resulting tree (dendrogram). First, there was a strong clustering of homotopic, left-right hemispheric areas. Second, cortical areas were concatenated in multiple, partially overlapping clusters. Third, the arrangement of the areas revealed a layout that closely resembled the actual layout of the cerebral cortex, namely an orderly progression from anterior to posterior. And fourth, the layout of the cortical areas in the tree conformed to principles of efficient, compact layout of components proposed by Cherniak. Since the tree was derived on the basis of the strength of neural correlations, these results document an orderly relation between functional interactions and layout, i.e., between structure and function.

  18. 团体心理辅导技术在职业核心能力培养中的应用%The Application of Group Counseling Techniques in The Professional Core Ability Training

    Institute of Scientific and Technical Information of China (English)

    赵娟

    2016-01-01

    Professional core ability refers to the basic ability except post professional ability of people in the professional career , which has universal applicability and wide range of mobility , and it is accompanied by a lifelong ability of sustainable development .The appli-cation of group psychological counseling to the cultivation of professional core competence has a strong feasibility .In the process of the cultivation of professional core ability , role play, group games, and a variety of group counseling technology can be used to change the traditional view of students and education , and to promote the students'consciousness , so as to improve the effect of teaching .%职业核心能力指人们职业生涯中岗位专业能力之外的基本能力,具有普遍的适用性和广泛的可迁移性,是伴随人终生的可持续发展的能力。将团体心理咨询技术应用到职业核心能力培养中具有较强的可行性。在职业核心能力培养过程中,可以通过角色扮演、团体游戏等多种团体心理辅导技术,改变传统学生观、教育观,促进学生自觉领悟,从而提高教育教学效果。

  19. 慢性非特异性腰痛与核心肌群的研究新进展%The Research Process of Chronic Non-specific Low Back Pain and Core Muscle Group

    Institute of Scientific and Technical Information of China (English)

    林鸿生; 罗平

    2015-01-01

    The segmental instability and control lost of lumbar vertebra is one of the most important factors that causes chronic non-specific low back pain (CNSLBP), increasing core muscle group especially the muscle strength and control ability of deep muscle groups of trunk is an efficient way to increase the stability and controlling of lumbar vertebra. This article would review the new process of CNSLBP and core muscle group, in or-der to provide some scientific theoretical basis for the treatment research of CNSLBP.%腰椎的节段性失稳和失控制是引起慢性非特异性腰痛(CNSLBP)的最重要的因素之一,提高核心肌群尤其是躯干深层肌群的肌力和控制能力是增加腰椎稳定性和控制性的有效途径.本文综述CNSLBP与核心肌群的新进展,为进一步研究CNSLBP的治疗方法提供科学的理论依据.

  20. 基于财务指标的南方物流集团核心竞争力评价%Evaluation of Core Competitivity of South Logistics Group Based on Financial Indexes

    Institute of Scientific and Technical Information of China (English)

    花雅南

    2014-01-01

    In this paper, from the perspective of financial management and the establishment of its evaluation index system, we studied the problem of the measurement and assessment of the core competitivity of the logistics enterprises, then surrounding the six major factors composing the core competitivity of these enterprises, built the overall evaluation index system, and at the end, used the AHP to analyze empirically the core competitivity of the three affiliates of the South Logistics Group.%从财务管理及其指标评价体系构建的角度研究了物流企业核心竞争力的衡量和测评问题,围绕构成物流企业核心竞争力的六大因素,从财务的角度构建了其整体评价指标体系,最后利用层次分析法对南方物流集团三家下属分公司核心竞争力进行了实证分析。

  1. DiGIR1 and NaGIR1: naturally occurring group I-like ribozymes with unique core organization and evolved biological role

    DEFF Research Database (Denmark)

    Johansen, Steinar; Einvik, Christer; Nielsen, Henrik

    2002-01-01

    introns (twin-ribozyme introns) in distantly related organisms. The Didymium GIR1 (DiGIR1) and Naegleria GIR1 (NaGIR1) share fundamental features in structural organization and reactivity, and display significant differences when compared to the related group I splicing ribozymes. GIR1 lacks...

  2. Ice Cores

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Records of past temperature, precipitation, atmospheric trace gases, and other aspects of climate and environment derived from ice cores drilled on glaciers and ice...

  3. Core BPEL

    DEFF Research Database (Denmark)

    Hallwyl, Tim; Højsgaard, Espen

    extensions. Combined with the fact that the language definition does not provide a formal semantics, it is an arduous task to work formally with the language (e.g. to give an implementation). In this paper we identify a core subset of the language, called Core BPEL, which has fewer and simpler constructs......, does not allow omissions, and does not contain ignorable elements. We do so by identifying syntactic sugar, including default values, and ignorable elements in WS-BPEL. The analysis results in a translation from the full language to the core subset. Thus, we reduce the effort needed for working...... formally with WS-BPEL, as one, without loss of generality, need only consider the much simpler Core BPEL. This report may also be viewed as an addendum to the WS-BPEL standard specification, which clarifies the WS-BPEL syntax and presents the essential elements of the language in a more concise way...

  4. Core BPEL

    DEFF Research Database (Denmark)

    Hallwyl, Tim; Højsgaard, Espen

    extensions. Combined with the fact that the language definition does not provide a formal semantics, it is an arduous task to work formally with the language (e.g. to give an implementation). In this paper we identify a core subset of the language, called Core BPEL, which has fewer and simpler constructs......, does not allow omissions, and does not contain ignorable elements. We do so by identifying syntactic sugar, including default values, and ignorable elements in WS-BPEL. The analysis results in a translation from the full language to the core subset. Thus, we reduce the effort needed for working...... formally with WS-BPEL, as one, without loss of generality, need only consider the much simpler Core BPEL. This report may also be viewed as an addendum to the WS-BPEL standard specification, which clarifies the WS-BPEL syntax and presents the essential elements of the language in a more concise way...

  5. Core benefits

    National Research Council Canada - National Science Library

    Keith, Brian W

    2010-01-01

    This SPEC Kit explores the core employment benefits of retirement, and life, health, and other insurance -benefits that are typically decided by the parent institution and often have significant governmental regulation...

  6. Chart Series

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Centers for Medicare and Medicaid Services (CMS) offers several different Chart Series with data on beneficiary health status, spending, operations, and quality...

  7. Case series

    African Journals Online (AJOL)

    abp

    2013-06-20

    Jun 20, 2013 ... Upper cervical spine injuries: a management of a series of 70 cases. El Fatemi ... women, with traffic accidents being the major traumatic cause. .... osteosynthesis is preferred to respect the biomechanics of the cervical spine ...

  8. Harmonic Series Meets Fibonacci Sequence

    Science.gov (United States)

    Chen, Hongwei; Kennedy, Chris

    2012-01-01

    The terms of a conditionally convergent series may be rearranged to converge to any prescribed real value. What if the harmonic series is grouped into Fibonacci length blocks? Or the harmonic series is arranged in alternating Fibonacci length blocks? Or rearranged and alternated into separate blocks of even and odd terms of Fibonacci length?

  9. Microwave assisted synthesis of a series of charge-transfer photosensitizers having quinoxaline-2(1H)-one as anchoring group onto TiO2 surface

    Science.gov (United States)

    Caicedo, Mauricio; Echeverry, Carlos A.; Guimarães, Robson R.; Ortiz, Alejandro; Araki, Koiti; Insuasty, Braulio

    2017-04-01

    In this work, we present the synthesis of novel donor-acceptor compounds based on 3-methylquinoxaline-2(1H)one which follow an easy synthetic route, involving Knoevenagel reaction with electron-donor groups such as N,N-dimethylaminobenzene, ferrocene, triphenylamine (TPA) and ((E)-4,4'-(ethene-1,2-diyl) bis (N,N-diphenylaniline). Additionally, the optical properties were measured by means of the absorption and emission spectroscopy suggesting a push-pull behavior which was further confirmed by electrochemical experiments. Finally, the quinoxaline-2(1H)one fragment not only bestow wide absorption, but also can chelate to titanium ions on the TiO2 surface, allowing a strong electron coupling between the excited-state energy level of the dyes and the conduction band of TiO2.

  10. Percutaneous injection of autologous, culture-expanded mesenchymal stem cells into carpometacarpal hand joints: a case series with an untreated comparison group.

    Science.gov (United States)

    Centeno, Christopher J; Freeman, Michael D

    2014-03-01

    In the present study, we describe six patients who received autologous mesenchymal stem cell (MSC) therapy for symptomatic carpometacarpal (CMC) joint and hand osteoarthritis (OA). Six patients who received injections of adult autologous culture expanded MSCs in their thumb CMC joints were followed for 1 year posttreatment, and matched with four procedure candidates who remained untreated. We observed positive outcomes in the treatment group for both symptoms and function related to the OA, compared with a reported worsening among the untreated controls. While these results should be interpreted with caution because of the small number of treated subjects and lack of placebo control and randomization, we find sufficient evidence for further investigation of MSC therapy as an alternative to more invasive surgery in patients with OA of the hand.

  11. Hydrogen-bond stabilized columnar discotic benzenetrisamides with pendant triphenylene groups

    NARCIS (Netherlands)

    Paraschiv, I.; Lange, de K.; Giesbers, M.; Lagen, van B.; Grozema, F.C.; Abellon, R.D.; Siebbeles, L.D.A.; Sudhölter, E.J.R.; Zuilhof, H.; Marcelis, A.T.M.

    2008-01-01

    series of 1,3,5-benzenetrisamide derivatives with three hexaalkoxytriphenylene pendant groups were prepared, in which the triphenylene groups are connected to the central 1,3,5-benzenetrisamide core through a flexible spacer. The length of this spacer, as well as the size of the ortho-substituent at

  12. Factorial invariance of child self-report across healthy and chronic health condition groups: a confirmatory factor analysis utilizing the PedsQLTM 4.0 Generic Core Scales.

    Science.gov (United States)

    Limbers, Christine A; Newman, Daniel A; Varni, James W

    2008-07-01

    The objective of the present study was to examine the factorial invariance of the PedsQL 4.0 Generic Core Scales for child self-report across 11,433 children ages 5-18 with chronic health conditions and healthy children. Multigroup Confirmatory Factor Analysis was performed specifying a five-factor model. Two multigroup structural equation models, one with constrained parameters and the other with unconstrained parameters, were proposed in order to compare the factor loadings across children with chronic health conditions and healthy children. Metric invariance (i.e., equal factor loadings) was demonstrated based on stability of the Comparative Fit Index (CFI) between the two models, and several additional indices of practical fit including the root mean squared error of approximation, the Non-normed Fit Index, and the Parsimony Normed Fit Index. The findings support an equivalent five-factor structure on the PedsQL 4.0 Generic Core Scales across healthy and chronic health condition groups. These findings suggest that when differences are found across chronic health condition and healthy groups when utilizing the PedsQL, these differences are more likely real differences in self-perceived health-related quality of life, rather than differences in interpretation of the PedsQL items as a function of health status.

  13. Multidimensional Recurrence Quantification Analysis (MdRQA) for the Analysis of Multidimensional Time-Series: A Software Implementation in MATLAB and Its Application to Group-Level Data in Joint Action.

    Science.gov (United States)

    Wallot, Sebastian; Roepstorff, Andreas; Mønster, Dan

    2016-01-01

    We introduce Multidimensional Recurrence Quantification Analysis (MdRQA) as a tool to analyze multidimensional time-series data. We show how MdRQA can be used to capture the dynamics of high-dimensional signals, and how MdRQA can be used to assess coupling between two or more variables. In particular, we describe applications of the method in research on joint and collective action, as it provides a coherent analysis framework to systematically investigate dynamics at different group levels-from individual dynamics, to dyadic dynamics, up to global group-level of arbitrary size. The Appendix in Supplementary Material contains a software implementation in MATLAB to calculate MdRQA measures.

  14. 客户信任网络下病毒式营销核心群体的挖掘%Mining the Core Group Based on Customer Trust Network for viral Marketing

    Institute of Scientific and Technical Information of China (English)

    夏秀峰; 赵秀涛

    2011-01-01

    At present, there is little work being done on choosing the best viral marketing strategy intelligently by using data mining. In order to mining the core group in a customer network, this paper defines a Customer Trust Network(CTN) based on trust statements between customers, builds a CTN Based Diffusion of Product Information(CTNBDPI) model, and then presents a mining algorithm called VMCGM( Viral Marketing Core Group Mining), along with an approach to design sequential marketing actions. The model does research on isolated customers'recommendation behavior by taking their characteristics and environmental factors into account. The experimental results show that the proposed model can better reflect the diffusion of product information in viral marketing , and demonstrates the algorithm has higher accuracy as well as lower time complexity than previous work.%目前,国内外对利用数据挖掘实现智能化制定病毒式营销策略的研究亟待深入.为了挖掘客户网络中的核心群体,定义了一种基于信任关系的客户信任网络CTN(Customer Trust Network),在此基础上创建了产品信息扩散模型CTNBDPI(CTN Based Diffusion of Product Information),提出了核心群体挖掘算法VMCGM(Viral Marketing Core Group Mining)与连续病毒式营销策略的制定方法.CTNBDPI模型引入客户特征与环境因素解决了孤立点的接受与推荐问题,实验证明可以更好地反映病毒式营销中产品信息扩散的规律,与已有研究相忧,VMCGM算法具有较低的时间复杂度和较高的准确性.

  15. Geomagnetism of earth's core

    Science.gov (United States)

    Benton, E. R.

    1983-01-01

    Instrumentation, analytical methods, and research goals for understanding the behavior and source of geophysical magnetism are reviewed. Magsat, launched in 1979, collected global magnetometer data and identified the main terrestrial magnetic fields. The data has been treated by representing the curl-free field in terms of a scalar potential which is decomposed into a truncated series of spherical harmonics. Solutions to the Laplace equation then extend the field upward or downward from the measurement level through intervening spaces with no source. Further research is necessary on the interaction between harmonics of various spatial scales. Attempts are also being made to analytically model the main field and its secular variation at the core-mantle boundary. Work is also being done on characterizing the core structure, composition, thermodynamics, energetics, and formation, as well as designing a new Magsat or a tethered satellite to be flown on the Shuttle.

  16. Geomagnetism of earth's core

    Science.gov (United States)

    Benton, E. R.

    1983-01-01

    Instrumentation, analytical methods, and research goals for understanding the behavior and source of geophysical magnetism are reviewed. Magsat, launched in 1979, collected global magnetometer data and identified the main terrestrial magnetic fields. The data has been treated by representing the curl-free field in terms of a scalar potential which is decomposed into a truncated series of spherical harmonics. Solutions to the Laplace equation then extend the field upward or downward from the measurement level through intervening spaces with no source. Further research is necessary on the interaction between harmonics of various spatial scales. Attempts are also being made to analytically model the main field and its secular variation at the core-mantle boundary. Work is also being done on characterizing the core structure, composition, thermodynamics, energetics, and formation, as well as designing a new Magsat or a tethered satellite to be flown on the Shuttle.

  17. Special series on "The meaning of behavioral medicine in the psychosomatic field" establishment of a core curriculum for behavioral science in Japan: The importance of such a curriculum from the perspective of psychology.

    Science.gov (United States)

    Shimazu, Akihito; Nakao, Mutsuhiro

    2016-01-01

    This article discusses the core curriculum for behavioral science, from the perspective of psychology, recommended by the Japanese Society of Behavioral Medicine and seeks to explain how the curriculum can be effectively implemented in medical and health-related departments. First, the content of the core curriculum is reviewed from the perspective of psychology. We show that the curriculum features both basic and applied components and that the basic components are closely related to various aspects of psychology. Next, we emphasize two points to aid the effective delivery of the curriculum: 1) It is necessary to explain the purpose and significance of basic components of behavioral science to improve student motivation; and 2) it is important to encourage student self-efficacy to facilitate application of the acquired knowledge and skills in clinical practice.

  18. Core strength training using a combination of home exercises and a dynamic sling system for the management of low back pain in pre-professional ballet dancers: a case series.

    Science.gov (United States)

    Kline, Jessica Beckmann; Krauss, John R; Maher, Sara F; Qu, Xianggui

    2013-01-01

    Estimates of low back pain prevalence in USA ballet dancers range from 8% to 23%. Lumbar stabilization and extensor muscle training has been shown to act as a hypoalgesic for low back pain. Timing and coordination of multifidi and transverse abdominis muscles are recognized as important factors for spinal stabilization. The purpose of this study was to explore the effects of training methods using home exercises and a dynamic sling system on core strength, disability, and low back pain in pre-professional ballet dancers. Five participants were randomly assigned to start a traditional unsupervised lumbar stabilization home exercise program (HEP) or supervised dynamic sling training to strengthen the core and lower extremities. Measurements were taken at baseline and at weeks 3 and 6 for disability using the patient specific functional scale (PSFS), pain using the Numerical Pain Rating System (NPRS), core strength and endurance using timed plank, side-plank, and bridge positions, and sciatic nerve irritability using the straight leg raise (SLR). Data were analyzed using descriptive statistics. From initial to final measurements, all participants demonstrated an improvement in strength and SLR range, and those with initial pain and disability reported relief of symptoms. These results suggest that dynamic sling training and a HEP may help to increase strength, decrease pain, and improve function in dancers without aggravating sciatic nerve irritation.

  19. Mining and recommending strategies based on core groups in Web viral marketing%Web病毒式营销核心群体挖掘与推荐策略

    Institute of Scientific and Technical Information of China (English)

    夏秀峰; 张晓飞

    2013-01-01

    Web病毒式营销已经成为电子商务领域中的重要营销策略,核心群体在其中发挥着重要的作用.为了挖掘核心群体并对其进行商品推荐,在Web客户信任网络(customer trust network,CTN)的基础上考虑了信任度、评价分数以及推荐次数等因素定义了影响度的概念,提出了以影响度为基础的节点网络影响集的构建方法以及基于网络影响集的核心群体挖掘算法MCGNIS(mining core group based on network-influence set),并以挖掘出的核心群体为对象建立了基于网络影响集的推荐模型RCGNIS(recommending model for core group based on network-influence set),设计了相应的推荐算法来计算商品对核心群体的可推荐度.实验证明,以节点网络影响集为基础挖掘出的核心群体在Web客户信任网络中具有较高的网络覆盖率(network-coverage,NC),推荐模型RCGNIS具有很好的推荐准确性,同时又保持了推荐的多样性.

  20. Exposures series

    OpenAIRE

    Stimson, Blake

    2011-01-01

    Reaktion Books’ Exposures series, edited by Peter Hamilton and Mark Haworth-Booth, is comprised of 13 volumes and counting, each less than 200 pages with 80 high-quality illustrations in color and black and white. Currently available titles include Photography and Australia, Photography and Spirit, Photography and Cinema, Photography and Literature, Photography and Flight, Photography and Egypt, Photography and Science, Photography and Africa, Photography and Italy, Photography and the USA, P...

  1. Core Java

    CERN Document Server

    Horstmann, Cay S

    2013-01-01

    Fully updated to reflect Java SE 7 language changes, Core Java™, Volume I—Fundamentals, Ninth Edition, is the definitive guide to the Java platform. Designed for serious programmers, this reliable, unbiased, no-nonsense tutorial illuminates key Java language and library features with thoroughly tested code examples. As in previous editions, all code is easy to understand, reflects modern best practices, and is specifically designed to help jumpstart your projects. Volume I quickly brings you up-to-speed on Java SE 7 core language enhancements, including the diamond operator, improved resource handling, and catching of multiple exceptions. All of the code examples have been updated to reflect these enhancements, and complete descriptions of new SE 7 features are integrated with insightful explanations of fundamental Java concepts.

  2. Inductive effect of methyl group in a series of methylated indoles: A graph theoretical analysis in the light of density functional theory and correlation with experimental charge transfer transition energies

    Indian Academy of Sciences (India)

    Amit S Tiwary; Asok K Mukherjee

    2013-07-01

    The inductive effect of methyl group has been quantified by expressing highest occupied molecular orbital (HOMO) and HOMO-1 energies of indole and a series of methylated indoles using a combination of graph theory (GT) and the Coulson-Longuett-Higgins perturbation method. By correlating these expressions with the corresponding Kohn-Sham orbital energies of the indoles obtained by density functional theory (DFT) calculation at the B3LYP/6-31++G(d,p) and M06-2X/6-31++G(d,p) levels of theory, the inductive effect parameter ℎ has been estimated; the Coulomb integral of -conjugated carbon atom also comes out from the analysis. A correlation of the GT results with the HOMO and HOMO-1 energies obtained by the HF/STO-3G method yield almost the same values of ℎ and . Finally, when these estimated ℎ and are used to calculate the vertical ionization potentials of the methylated indoles in the series, an excellent correlation with experimental charge transfer transition energies of their molecular complexes with tetracyanoethylene is obtained which complies with Mulliken’s theory of charge transfer.

  3. 基于51系列单片机的并行多任务系统内核设计%Design of Multitasking System Core Based on 51 Series Microcontroller

    Institute of Scientific and Technical Information of China (English)

    任龙平; 刘清平

    2016-01-01

    With the development in the intelligent control domain, running single task or looping multi-mission at foreground and background, the system can seldom satisfy some real-time multitasking control. So the multitasking operating system has become an embedded research focus. The operating system core adopts AT89C52RC MCU as the carrier and uses C language to program on keil platform for the development environment in this paper. The sys-tem core has characteristics of multiple task creation and the task delay service, by using the preemptive scheduling algorithm.%随着智能控制领域的发展,单任务或者任务轮循式前后台的系统往往满足不了具有实时性的多任务控制,所以多任务操作系统一直都作为嵌入式研究的重点。本文以keil平台为开发环境,采用AT89C52RC单片机为载体,选用C语言编程实现操作系统内核,其内核采用抢占式调度算法,具有多任务创建与任务延时服务的特性。

  4. Exploration and exploitation of homologous series of bis(acrylamidoalkanes containing pyridyl and phenyl groups: β-sheet versus two-dimensional layers in solid-state photochemical [2 + 2] reactions

    Directory of Open Access Journals (Sweden)

    Mousumi Garai

    2015-09-01

    Full Text Available The homologous series of phenyl and pyridyl substituted bis(acrylamidoalkanes have been synthesized with the aim of systematic analysis of their crystal structures and their solid-state [2 + 2] reactivities. The changes in the crystal structures with respect to a small change in the molecular structure, that is by varying alkyl spacers between acrylamides and/or by varying the end groups (phenyl, 2-pyridyl, 3-pyridyl, 4-pyridyl on the C-terminal of the amide, were analyzed in terms of hydrogen-bonding interference (N—H...Npy versus N—H...O=C and network geometries. In this series, a greater tendency towards the formation of N—H...O hydrogen bonds (β-sheets and two-dimensional networks over N—H...N hydrogen bonds was observed. Among all the structures seven structures were found to have the required alignments of double bonds for the [2 + 2] reaction such that the formations of single dimer, double dimer and polymer are facilitated. However, only four structures were found to exhibit such a solid-state [2 + 2] reaction to form a single dimer and polymers. The two-dimensional hydrogen-bonding layer via N—H...O hydrogen bonds was found to promote solid-state [2 + 2] photo-polymerization in a single-crystal-to-single-crystal manner. Such two-dimensional layers were encountered only when the spacer between acryl amide moieties is butyl. Only four out of the 16 derivatives were found to form hydrates, two each from 2-pyridyl and 4-pyridyl derivatives. The water molecules in these structures govern the hydrogen-bonding networks by the formation of an octameric water cluster and one-dimensional zigzag water chains. The trends in the melting points and densities were also analyzed.

  5. Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group.

    Science.gov (United States)

    Bungard, Christopher J; Williams, Peter D; Ballard, Jeanine E; Bennett, David J; Beaulieu, Christian; Bahnck-Teets, Carolyn; Carroll, Steve S; Chang, Ronald K; Dubost, David C; Fay, John F; Diamond, Tracy L; Greshock, Thomas J; Hao, Li; Holloway, M Katharine; Felock, Peter J; Gesell, Jennifer J; Su, Hua-Poo; Manikowski, Jesse J; McKay, Daniel J; Miller, Mike; Min, Xu; Molinaro, Carmela; Moradei, Oscar M; Nantermet, Philippe G; Nadeau, Christian; Sanchez, Rosa I; Satyanarayana, Tummanapalli; Shipe, William D; Singh, Sanjay K; Truong, Vouy Linh; Vijayasaradhi, Sivalenka; Wiscount, Catherine M; Vacca, Joseph P; Crane, Sheldon N; McCauley, John A

    2016-07-14

    A novel HIV protease inhibitor was designed using a morpholine core as the aspartate binding group. Analysis of the crystal structure of the initial lead bound to HIV protease enabled optimization of enzyme potency and antiviral activity. This afforded a series of potent orally bioavailable inhibitors of which MK-8718 was identified as a compound with a favorable overall profile.

  6. On-line core axial power distribution synthesis method from in-core and ex-core neutron detectors

    Energy Technology Data Exchange (ETDEWEB)

    In, Wang Kee; Cho, Byung Oh [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-10-01

    This document describes the methodology in detail and the synthesis coefficients of the Fourier series expansion and the cubic spline synthesis techniques. A computer program was developed to generate the synthesis coefficients and the core power distribution. For the illustration, various axial power shapes for YGN 3 Cycle 1 and SMART were synthesized using the simulated in-core and/or ex-core detector signals. The results of this study will be useful to select the best synthesis method for the SMART core monitoring and protection systems and to evaluate the accuracy of the synthesized power shape. 4 refs., 13 figs., 5 tabs. (Author)

  7. DCP Series

    Directory of Open Access Journals (Sweden)

    Philip Stearns

    2011-06-01

    Full Text Available Photo essay. A collection of Images produced by intentionally corrupting the circuitry of a Kodak DC280 2 MP digitalcamera. By rewiring the electronics of a digital camera, glitched images are produced in a manner that parallels chemically processing unexposed film or photographic paper to produce photographic images without exposure to light. The DCP Series of Digital Images are direct visualizations of data generated by a digital camera as it takes a picture. Electronic processes associated with the normal operations of the camera, which are usually taken for granted, are revealed through an act of intervention. The camera is turned inside­out through complexes of short­circuits, selected by the artist, transforming the camera from a picture taking device to a data capturing device that renders raw data (electronic signals as images. In essence, these images are snap­shots of electronic signals dancing through the camera's circuits, manually rerouted, written directly to the on­board memory device. Rather than seeing images of the world through a lens, we catch a glimpse of what the camera sees when it is forced to peer inside its own mind.

  8. Modeling Core Collapse Supernovae

    Science.gov (United States)

    Mezzacappa, Anthony

    2017-01-01

    Core collapse supernovae, or the death throes of massive stars, are general relativistic, neutrino-magneto-hydrodynamic events. The core collapse supernova mechanism is still not in hand, though key components have been illuminated, and the potential for multiple mechanisms for different progenitors exists. Core collapse supernovae are the single most important source of elements in the Universe, and serve other critical roles in galactic chemical and thermal evolution, the birth of neutron stars, pulsars, and stellar mass black holes, the production of a subclass of gamma-ray bursts, and as potential cosmic laboratories for fundamental nuclear and particle physics. Given this, the so called ``supernova problem'' is one of the most important unsolved problems in astrophysics. It has been fifty years since the first numerical simulations of core collapse supernovae were performed. Progress in the past decade, and especially within the past five years, has been exponential, yet much work remains. Spherically symmetric simulations over nearly four decades laid the foundation for this progress. Two-dimensional modeling that assumes axial symmetry is maturing. And three-dimensional modeling, while in its infancy, has begun in earnest. I will present some of the recent work from the ``Oak Ridge'' group, and will discuss this work in the context of the broader work by other researchers in the field. I will then point to future requirements and challenges. Connections with other experimental, observational, and theoretical efforts will be discussed, as well.

  9. El mono y el cacao: la búsqueda de un mito a través de los relieves del Grupo de la Serie Inicial de Chichén Itzá Monkey and Cacao: in Search of a Myth Through the Initial Series Group Reliefs in Chichén Itzá

    Directory of Open Access Journals (Sweden)

    Martha Ilia Nájera Coronado

    2012-01-01

    Full Text Available Recientes estudios sobre el cacao han subrayado la relevancia del árbol y de su fruto en diferentes ámbitos de la cultura maya y podría afirmarse que, después del maíz, fue la planta más venerada; su valor destaca en la esfera económica, en la social y, por supuesto, también en la religiosa. A pesar de ello se desconocen mitos sobre cómo los hombres llegaron a obtenerlo; por ello, con base en el modelo mítico mesoamericano del maíz, se propone una interpretación sustentada principalmente en el análisis de algunos de los relieves del Grupo de la Serie Inicial ubicado en Chichén Itzá, en la que el simio juega un papel relevante.Recent studies about cacao symbolism have stressed the importance of this plant and its bean in several contexts of ancient Maya culture, sustaining the assumption that it was the most revered plant after corn. Its value stands out in economic and social terms and, of course, in religious contexts. However, we do not know the mythical beliefs related with its procurement for the human beings; in this paper we propose a possible interpretation, based on the maize mythical model and supported by several representations from the Initial Series Group of Chichén Itzá, where monkeys play an important role.

  10. PHYLOMETABOLIC CORE OF INTESTINAL MICROBIOTA

    Directory of Open Access Journals (Sweden)

    S. I. Sitkin

    2015-01-01

    Full Text Available The authors  discuss the  theory  of human  superorganism and its microbiota (microbiome, whose mutualistic  interactions  is realized within the  microbiota – gut – brain axis that includes endocrine, immune and neurohumoral pathways. The newest concepts  of microbiome enterotypes and core microbiota  are  presented, which are  important  for understanding of the  role of symbiotic  microorganisms  in human  vital activities, for explanation of pathophysiology of many  chronic  human  diseases  (beyond  gastrointestinal disorders, as well as for the  search of effective therapeutic targets. As highly promising are considered  the functional approaches to studies  of microbiota  that  allowed to formulate the concept  of phylometabolic (phylofunctional core. This is a series of evolutionally stable microorganisms  responsible  for majority of the  main microbiome  functions, such as fermentation  of polysaccharides  (glycans, production of short-chain  fatty acids (butyrate, propionate, acetate, hydrogen  utilization, production of lactate, metabolism of aminoacids, bile acids, choline, production  of vitamins and  some  biologically active substances – anti-inflammatory, anti-microbial, immunostimulatory. The authors are first to describe the main functional groups  of microorganisms  of   gut microbiota phylometabolic core, providing key metabolic functions, as well as the leading characteristics of the  phylometabolic core as such. The perspectives  of modification  of composition  and functions  of phylometabolic microbiota  core are discussed based on metabiotics  as a virtually new class of therapeutic agents. A hypothesis has been proposed that  the  ratios  between main  components of the key gut microbiota may reflect fundamental  processed  related  to a mutualistic interactions between microbiota and human body, as well as they may serve as effective biological markers of

  11. Algebraic Groups

    DEFF Research Database (Denmark)

    2007-01-01

    The workshop continued a series of Oberwolfach meetings on algebraic groups, started in 1971 by Tonny Springer and Jacques Tits who both attended the present conference. This time, the organizers were Michel Brion, Jens Carsten Jantzen, and Raphaël Rouquier. During the last years, the subject...... of algebraic groups (in a broad sense) has seen important developments in several directions, also related to representation theory and algebraic geometry. The workshop aimed at presenting some of these developments in order to make them accessible to a "general audience" of algebraic group......-theorists, and to stimulate contacts between participants. Each of the first four days was dedicated to one area of research that has recently seen decisive progress: \\begin{itemize} \\item structure and classification of wonderful varieties, \\item finite reductive groups and character sheaves, \\item quantum cohomology...

  12. Modeling of Pulsed Transformer with Nanocrystalline Cores

    Directory of Open Access Journals (Sweden)

    Amir Baktash

    2014-07-01

    Full Text Available Recently tape wound cores, due to their excellent properties, are widely used in transformers for pulsed or high frequency applications. The spiral structure of these cores affects the flux distribution inside the core and causes complication of the magnetic analysis and consequently the circuit analysis. In this paper, a model based on reluctance networks method is used to analyze the magnetic flux in toroidal wound cores and losses calculation. A Preisach based hysteresis model is included in the model to consider the nonlinear characteristic of the core. Magnetic losses are calculated by having the flux density in different points of the core and using the hysteresis model. A transformer for using in a series resonant converter is modeled and implemented. The modeling results are compared with experimental measurements and FEM results to evaluate the validity of the model. Comparisons show the accuracy of the model besides its simplicity and fast convergence.

  13. Overview of the HUPO Plasma Proteome Project: Results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database

    Energy Technology Data Exchange (ETDEWEB)

    Omenn, Gilbert; States, David J.; Adamski, Marcin; Blackwell, Thomas W.; Menon, Rajasree; Hermjakob, Henning; Apweiler, Rolf; Haab, Brian B.; Simpson, Richard; Eddes, James; Kapp, Eugene; Moritz, Rod; Chan, Daniel W.; Rai, Alex J.; Admon, Arie; Aebersold, Ruedi; Eng, Jimmy K.; Hancock, William S.; Hefta, Stanley A.; Meyer, Helmut; Paik, Young-Ki; Yoo, Jong-Shin; Ping, Peipei; Pounds, Joel G.; Adkins, Joshua N.; Qian, Xiaohong; Wang, Rong; Wasinger, Valerie; Wu, Chi Yue; Zhao, Xiaohang; Zeng, Rong; Archakov, Alexander; Tsugita, Akira; Beer, Ilan; Pandey, Akhilesh; Pisano, Michael; Andrews, Philip; Tammen, Harald; Speicher, David W.; Hanash, Samir M.

    2005-08-13

    HUPO initiated the Plasma Proteome Project (PPP) in 2002. Its pilot phase has (1) evaluated advantages and limitations of many depletion, fractionation, and MS technology platforms; (2) compared PPP reference specimens of human serum and EDTA, heparin, and citrate-anticoagulated plasma; and (3) created a publicly-available knowledge base (www.bioinformatics. med.umich.edu/hupo/ppp; www.ebi.ac.uk/pride). Thirty-five participating laboratories in 13 countries submitted datasets. Working groups addressed (a) specimen stability and protein concentrations; (b) protein identifications from 18 MS/MS datasets; (c) independent analyses from raw MS-MS spectra; (d) search engine performance, subproteome analyses, and biological insights; (e) antibody arrays; and (f) direct MS/SELDI analyses. MS-MS datasets had 15 710 different International Protein Index (IPI) protein IDs; our integration algorithm applied to multiple matches of peptide sequences yielded 9504 IPI proteins identified with one or more peptides and 3020 proteins identified with two or more peptides (the Core Dataset). These proteins have been characterized with Gene Ontology, InterPro, Novartis Atlas, OMIM, and immunoassay based concentration determinations. The database permits examination of many other subsets, such as 1274 proteins identified with three or more peptides. Reverse protein to DNA matching identified proteins for 118 previously unidentified ORFs. We recommend use of plasma instead of serum, with EDTA (or citrate) for anticoagulation. To improve resolution, sensitivity and reproducibility of peptide identifications and protein matches, we recommend combinations of depletion, fractionation, and MS/MS technologies, with explicit criteria for evaluation of spectra, use of search algorithms, and integration of homologous protein matches. This Special Issue of PROTEOMICS presents papers integral to the collaborative analysis plus many reports of supplementary work on various aspects of the PPP workplan

  14. Synthesis and property studies on a series of novel triazole derivatives containing different aryl group units%新型芳环桥连三氮唑衍生物的合成及其性质研究

    Institute of Scientific and Technical Information of China (English)

    王婷; 朱槿; 王金云; 黄晴菲; 王启卫

    2016-01-01

    A series of compounds containingtriazole group were synthesized via the coupling reaction between 1,2-bis[chloro(phen-yl) methylidene] hydrazine and different aniline moiety. All of them were fully characterized by proton nuclear magnetic resonance spectroscopy or mass spectrometry methods. Thermal stability,optical and electrochemical properties of these compounds were stud-ied by TGA,DSC,UV-Vis and cyclic voltammetry. These materials exhibited good thermal stabilities and had the potential to be fab-ricated into OLED devices as electron-transport materials. To further evaluate the feasibility of those new materials for optoelectronic applications,(TD-)DFT((time-dependent)density functional theory)calculations were performed to characterize the electronic structures and absorption transition properties of these new compounds.%报道了以1,2-双[氯(苯基)亚甲基]腙与一系列含苯胺基团的化合物进行缩合反应,合成了一系列含有不同连接基团结构的三唑衍生物,其结构经1 H NMR或MS表征.用TGA,DSC,UV-Vis和循环伏安法研究了化合物的热稳定性、光学和电化学性质,其结果表明这一系列化合物具有良好的热稳定性和优良的光学及电化学性质,并且采用(含时)密度泛函理论方法研究了其电子结构和吸收跃迁性质.结果显示该类化合物作为电子传输材料在OLEDs器件中具有潜在的应用价值.

  15. Thoughts on " false citations" among a series of published articles by a research group%对某课题组所发表系列论文中“假引”现象的思考

    Institute of Scientific and Technical Information of China (English)

    王福军; 冷怀明; 郭建秀

    2011-01-01

    Through analyzing some " false citations" among a series of articles published by a research group, we elaborates the limitations of impact factor as it has been used to evaluate the academic quality of a single article, and identify the role of "false citation" in this evaluation. We advocate that we need to make a comprehensive analysis to evaluate the academic quality of a single article, including impact factor, total citation of the journal, comments from peer reviewers, and its social values. We hope that we should understand the role of impact factor in evaluating academic quality of a single article, and thus take some measures to reduce and even to put an end of false citation.%通过对某课题组所发表系列论文中“假引”现象的分析,阐述以期刊影响因子作为单篇论文学术质量评价指标的局限性及正确认识“假引”现象对单篇论文学术质量评价的意义。认为对于单篇论文应运用期刊影响因子、总被引频次并结合同行评议及论文的社会价值等进行综合评价,并应采取相应的措施减少甚至杜绝“假引”问题。

  16. Are medical residents a "core group" for future improvement of influenza vaccination coverage in health-care workers? A study among medical residents at the University Hospital of Palermo (Sicily).

    Science.gov (United States)

    Amodio, Emanuele; Tramuto, Fabio; Maringhini, Guido; Asciutto, Rosario; Firenze, Alberto; Vitale, Francesco; Costantino, Claudio; Calamusa, Giuseppe

    2011-10-19

    residents appears to be habitual, with little comprehension of the rationale and logic for vaccination, including the need to be vaccinated to protect patients from nosocomial influenza infection. Our study suggests the importance of prioritizing residents for vaccination campaigns, as they represent "the future" and include a core group that habitually accepts vaccination.

  17. Dual-core antiresonant hollow core fibers.

    Science.gov (United States)

    Liu, Xuesong; Fan, Zhongwei; Shi, Zhaohui; Ma, Yunfeng; Yu, Jin; Zhang, Jing

    2016-07-25

    In this work, dual-core antiresonant hollow core fibers (AR-HCFs) are numerically demonstrated, based on our knowledge, for the first time. Two fiber structures are proposed. One is a composite of two single-core nested nodeless AR-HCFs, exhibiting low confinement loss and a circular mode profile in each core. The other has a relatively simple structure, with a whole elliptical outer jacket, presenting a uniform and wide transmission band. The modal couplings of the dual-core AR-HCFs rely on a unique mechanism that transfers power through the air. The core separation and the gap between the two cores influence the modal coupling strength. With proper designs, both of the dual-core fibers can have low phase birefringence and short modal coupling lengths of several centimeters.

  18. Restitution report of the working group called 'access to the information' implemented in the framework of the public debate EPR ''head of series'' at Flamanville; Rapport de restitution du groupe de travail dit ''Acces a l'information'' Groupe de travail mis en place dans le cadre du debat public EPR ''tete de serie'' a Flamanville

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-02-15

    The works realized by this working group show some strong conclusions. The citizen confidence in the information access availability must be reinforced. The existence of secrets protecting the industrialists and the Nation interests seems all the more legitimate since they are well limited.The respect of the industrial and commercial secret is not an opposition to a better access to the nuclear safety documents. The defense secret is an indispensable element of the nuclear safety but its role and limits must be debated. (A.L.B.)

  19. Core stability training on lower limb balance strength.

    Science.gov (United States)

    Dello Iacono, Antonio; Padulo, Johnny; Ayalon, Moshe

    2016-01-01

    This study aimed to assess the effects of core stability training on lower limbs' muscular asymmetries and imbalances in team sport. Twenty footballers were divided into two groups, either core stability or control group. Before each daily practice, core stability group (n = 10) performed a core stability training programme, while control group (n = 10) did a standard warm-up. The effects of the core stability training programme were assessed by performing isokinetic tests and single-leg countermovement jumps. Significant improvement was found for knee extensors peak torque at 3.14 rad · s(-1) (14%; P core stability group. The jump tests showed a significant reduction in the strength asymmetries in core stability group (-71.4%; P = 0.02) while a concurrent increase was seen in the control group (33.3%; P core exercises for optimal lower limbs strength balance development in young soccer players.

  20. An Antarctic ice core recording both supernovae and solar cycles

    CERN Document Server

    Motizuki, Yuko; Makishima, Kazuo; Bamba, Aya; Nakai, Yoichi; Yano, Yasushige; Igarashi, Makoto; Motoyama, Hideaki; Kamiyama, Kokichi; Suzuki, Keisuke; Imamura, Takashi

    2009-01-01

    Ice cores are known to be rich in information regarding past climates, and the possibility that they record astronomical phenomena has also been discussed. Rood et al. were the first to suggest, in 1979, that nitrate ion (NO3-) concentration spikes observed in the depth profile of a South Pole ice core might correlate with the known historical supernovae (SNe), Tycho (AD 1572), Kepler (AD 1604), and SN 1181 (AD 1181). Their findings, however, were not supported by subsequent examinations by different groups using different ice cores, and the results have remained controversial and confusing. Here we present a precision analysis of an ice core drilled in 2001 at Dome Fuji station in Antarctica. It revealed highly significant three NO3- spikes dating from the 10th to the 11th century. Two of them are coincident with SN 1006 (AD 1006) and the Crab Nebula SN (AD 1054), within the uncertainty of our absolute dating based on known volcanic signals. Moreover, by applying time-series analyses to the measured NO3- con...

  1. Time series prediction in agroecosystems

    Science.gov (United States)

    Cortina-Januchs, M. G.; Quintanilla-Dominguez, J.; Vega-Corona, A.; Andina, D.

    2012-04-01

    This work proposes a novel model to predict time series such as frost, precipitation, temperature, solar radiation, all of them important variables for the agriculture process. In the proposed model, Artificial Neural Networks (ANN) combined with clustering algorithms and sensor data fusion are used. The real time series are obtained from different sensors. The clustering algorithms find relationships between variables, clustering involves the task of dividing data sets, which assigns the same label to members who belong to the same group, so that each group is homogeneous and distinct from the others. Those relationships provide information to the ANN in order to obtain the time series prediction. The most important issue of ANN in time series prediction is generalization, which refers to their ability to produce reasonable predictions on data sets other than those used for the estimation of the model parameters.

  2. Henoch-Schönlein purpura in adults: a case series from a multidisciplinary study group Púrpura de Henoch-Schönlein em adultos: uma série de casos de um grupo de estudo multidisciplinar

    Directory of Open Access Journals (Sweden)

    Boris A. Cruz

    2006-12-01

    Full Text Available BACKGROUND: Henoch-Schönlein purpura (HSP is a systemic vasculitis involving small vessels with the deposition of immune complexes containing IgA. It has been extensively studied in children, but in adults, its natural history is much less known. OBJECTIVES: to report a series of patients with HSP presenting in their adulthood. PATIENTS AND METHODS: the Minas Gerais Vasculitis Study Group´s Members (MGVSG were invited to report patients with HSP who appeared in their adulthood. A standardized retrospective chart review was done. RESULTS: eleven patients, two male and nine female, age 39.4 +/- 20.1 yearsold were studied. Nine patients presented purpura, seven presented arthritis, four patients had gastrointestinal involvement and ten patients (91% presented glomerulonephritis (GN. Eight patients were subjected to renal biopsies. Six of them presented endocapillary proliferative GN and only two of them had minimal mesangial proliferation. In the other three patients, HSP was confirmed by skin biopsies. All patients received steroids, in five of them steroids were combined with other immunosuppressive agents. After a follow-up of 39.0 +/- 64.6 months, four patients (36% presented impairment of renal function, but only one (9% developed end stage renal disease and was successfully appeared to renal transplantation. At the end of follow-up, seven patients (64% are in complete remission and four in partial remission. CONCLUSION: in adulthood, HSP represents a distinct clinical syndrome with a higher frequency of renal involvement and more severe systemic vasculitis. Nevertheless, the final outcome in this series was as good as reported in children, maybe due to aggressive immunosuppressive therapy.INTRODUÇÃO: púrpura de Henoch-Schönlein (PHS é uma vasculite sistêmica que acomete vasos de pequeno calibre com depósitos de imunocomplexos contendo IgA. Esta vasculite já foi extensamente estudada em crianças, mas sua história natural em adultos

  3. Animal MRI Core

    Data.gov (United States)

    Federal Laboratory Consortium — The Animal Magnetic Resonance Imaging (MRI) Core develops and optimizes MRI methods for cardiovascular imaging of mice and rats. The Core provides imaging expertise,...

  4. Classification of Promoters Based on the Combination of Core Promoter Elements Exhibits Different Histone Modification Patterns

    Science.gov (United States)

    Natsume-Kitatani, Yayoi; Mamitsuka, Hiroshi

    2016-01-01

    Four different histones (H2A, H2B, H3, and H4; two subunits each) constitute a histone octamer, around which DNA wraps to form histone-DNA complexes called nucleosomes. Amino acid residues in each histone are occasionally modified, resulting in several biological effects, including differential regulation of transcription. Core promoters that encompass the transcription start site have well-conserved DNA motifs, including the initiator (Inr), TATA box, and DPE, which are collectively called the core promoter elements (CPEs). In this study, we systematically studied the associations between the CPEs and histone modifications by integrating the Drosophila Core Promoter Database and time-series ChIP-seq data for histone modifications (H3K4me3, H3K27ac, and H3K27me3) during development in Drosophila melanogaster via the modENCODE project. We classified 96 core promoters into four groups based on the presence or absence of the TATA box or DPE, calculated the histone modification ratio at the core promoter region, and transcribed region for each core promoter. We found that the histone modifications in TATA-less groups were static during development and that the core promoters could be clearly divided into three types: i) core promoters with continuous active marks (H3K4me3 and H3K27ac), ii) core promoters with a continuous inactive mark (H3K27me3) and occasional active marks, and iii) core promoters with occasional histone modifications. Linear regression analysis and non-linear regression by random forest showed that the TATA-containing groups included core promoters without histone modifications, for which the measured RNA expression values were not predictable accurately from the histone modification status. DPE-containing groups had a higher relative frequency of H3K27me3 in both the core promoter region and transcribed region. In summary, our analysis showed that there was a systematic link between the existence of the CPEs and the dynamics, frequency and influence

  5. Classification of Promoters Based on the Combination of Core Promoter Elements Exhibits Different Histone Modification Patterns.

    Directory of Open Access Journals (Sweden)

    Yayoi Natsume-Kitatani

    Full Text Available Four different histones (H2A, H2B, H3, and H4; two subunits each constitute a histone octamer, around which DNA wraps to form histone-DNA complexes called nucleosomes. Amino acid residues in each histone are occasionally modified, resulting in several biological effects, including differential regulation of transcription. Core promoters that encompass the transcription start site have well-conserved DNA motifs, including the initiator (Inr, TATA box, and DPE, which are collectively called the core promoter elements (CPEs. In this study, we systematically studied the associations between the CPEs and histone modifications by integrating the Drosophila Core Promoter Database and time-series ChIP-seq data for histone modifications (H3K4me3, H3K27ac, and H3K27me3 during development in Drosophila melanogaster via the modENCODE project. We classified 96 core promoters into four groups based on the presence or absence of the TATA box or DPE, calculated the histone modification ratio at the core promoter region, and transcribed region for each core promoter. We found that the histone modifications in TATA-less groups were static during development and that the core promoters could be clearly divided into three types: i core promoters with continuous active marks (H3K4me3 and H3K27ac, ii core promoters with a continuous inactive mark (H3K27me3 and occasional active marks, and iii core promoters with occasional histone modifications. Linear regression analysis and non-linear regression by random forest showed that the TATA-containing groups included core promoters without histone modifications, for which the measured RNA expression values were not predictable accurately from the histone modification status. DPE-containing groups had a higher relative frequency of H3K27me3 in both the core promoter region and transcribed region. In summary, our analysis showed that there was a systematic link between the existence of the CPEs and the dynamics, frequency

  6. Graded core/shell semiconductor nanorods and nanorod barcodes

    Science.gov (United States)

    Alivisatos, A. Paul; Scher, Erik C.; Manna, Liberato

    2009-05-19

    Disclosed herein is a graded core/shell semiconductor nanorod having at least a first segment of a core of a Group II-VI, Group III-V or a Group IV semiconductor, a graded shell overlying the core, wherein the graded shell comprises at least two monolayers, wherein the at least two monolayers each independently comprise a Group II-VI, Group III-V or a Group IV semiconductor.

  7. 利丰公司核心扩张模式与供应链策略研究%Study on Core Expansion Mode and Supply Chain Strategy of Li&Fung Group

    Institute of Scientific and Technical Information of China (English)

    谢政谕

    2011-01-01

    运用Zook的核心扩张理论,从产品扩张、地理扩张、价值链扩张、通路扩张、顾客扩张和新事业扩张六个方面分析了利丰公司的核心扩张模式,并对利丰公司支持这种核心扩张模式的供应链策略进行了分析.%The paper uses Zook's Core Expansion Theory to analyze Li&Fung's core expansion mode from the following six dimensions: product expansion, geography expansion, value chain expansion, channel expansion, customer expansion and new business expansion and also probes into the supply chain strategy which supports the core expansion mode.

  8. Ecological risk assessment of land use in core area of Changsha-Zhuzhou-Xiangtan urban group%长株潭城市群核心区土地利用生态风险评价

    Institute of Scientific and Technical Information of China (English)

    傅丽华; 谢炳庚; 张晔; 邓楚雄; 左婕

    2011-01-01

    With the rapid development of Changsha - Zhuzhou - Xiangtan Urban group, the change of land use structure and mode caused by human' s activities has formed, a great ecological and environment pressure . The land use ecological risk assessment based on GIS and landscape ecology were used for selecting the typical transect core area of this urban group as the study area, and the Xiangjiang River shoreline as sample belt. Based on the "Source" and "sink" theory with the function of landscape ecological risk assessment, the index analysis framework and the ecological risk assessment model for spatial analysis and comprehenive evaluation was established.The results show that the high ecological risk is in the built-up area of Changsha, Zhuzhou and Xiangtan are followed. Among them, the risk index value is decreased from urban built-up areas to urban fringe. The ecological risk index in the junction of three cities is low. According to the character and distribution of the ecological risk, the corresponding risk control management strategies are proposed.%随着长株潭城市群的快速发展,人类活动导致的土地利用结构及方式改变对生态环境构成了巨大压力.运用GIS和景观生态学方法的土地利用生态风险评价,以长株潭城市群核心区为研究区域,选择湘江岸线为典型样带,建立了基于"源"与"汇"景观功能的土地利用生态风险评价指标体系,并构建了评价模型,对生态风险进行了空间分析和综合评价.结果表明,长沙市建成区的土地利用生态风险指数整体最高,株洲和湘潭居次.其中,从城市群建成区向外,风险指数逐渐降低,长沙、株洲、湘潭三市交界处生态风险指数也较低.根据研究区域生态风险状况、变化和分布特征,提出了相应的风险调控策略和管理方法,为实现区域土地利用与生态、社会、经济的可持续发展提供决策依据.

  9. Growth outside the core.

    Science.gov (United States)

    Zook, Chris; Allen, James

    2003-12-01

    Growth in an adjacent market is tougher than it looks; three-quarters of the time, the effort fails. But companies can change those odds dramatically. Results from a five-year study of corporate growth conducted by Bain & Company reveal that adjacency expansion succeeds only when built around strong core businesses that have the potential to become market leaders. And the best place to look for adjacency opportunities is inside a company's strongest customers. The study also found that the most successful companies were able to consistently, profitably outgrow their rivals by developing a formula for pushing out the boundaries of their core businesses in predictable, repeatable ways. Companies use their repeatability formulas to expand into any number of adjacencies. Some companies make repeated geographic moves, as Vodafone has done in expanding from one geographic market to another over the past 13 years, building revenues from $1 billion in 1990 to $48 billion in 2003. Others apply a superior business model to new segments. Dell, for example, has repeatedly adapted its direct-to-customer model to new customer segments and new product categories. In other cases, companies develop hybrid approaches. Nike executed a series of different types of adjacency moves: it expanded into adjacent customer segments, introduced new products, developed new distribution channels, and then moved into adjacent geographic markets. The successful repeaters in the study had two common characteristics. First, they were extraordinarily disciplined, applying rigorous screens before they made an adjacency move. This discipline paid off in the form of learning curve benefits, increased speed, and lower complexity. And second, in almost all cases, they developed their repeatable formulas by studying their customers and their customers' economics very, very carefully.

  10. A Bibliography of Canadian Day Care Research. Report of the Task Force on Child Care: Series 6 = Bibliographie des etudes sur la garde des enfants au Canada. Rapport du groupe d'etude sur la garde des enfants.

    Science.gov (United States)

    Pence, Alan R.

    Part of an effort to provide detailed analyses of issues of special relevance to child care and parental leave policies and the effects of these issues on the changing Canadian family, this volume, the last in a series of six, provides a bibliography of Canadian day care research. (RH)

  11. Report and Selected Papers of the Expert Group Meeting on Organizational Aspects of Integrating Family Planning with Development Programmes (Bangkok, 29 November-4 December 1976). Asian Population Studies Series No. 36.

    Science.gov (United States)

    United Nations Economic and Social Commission for Asia and the Pacific, Bangkok (Thailand).

    This publication reports the eleventh meeting in a series of regional seminars convened by the Economic and Social Commission for Asia and the Pacific (ESCAP) on the subject of fertility and family planning. The main objectives of the meeting were to: (1) identify the characteristics of regional integrated family planning programs; (2) identify…

  12. The Fluxgate Ring-Core Internal Field

    DEFF Research Database (Denmark)

    Primdahl, Fritz; Brauer, Peter; Merayo, José M.G.

    2002-01-01

    A large number of measured demagnetizing factors for fluxgate ring cores of a wide range of cross section shapes have been compiled from the literature and plotted against the core cross-sectional area over the squared mean core diameter. The points group close to a straight line through the origin...... that the demagnetizing factor for thin rings is proportional to the ring cross-sectional area divided by the diameter squared....

  13. Analysis of low-frequency climate periodicity in lacustrine sediments from the Enciso Group (Lower Cretaceous, Cameros basin, La Rioja, Spain) and its application to the correlation and dating of the series; Analisis de la periodicidad climatica de baja frecuencia registrada en los sedimentos lacustres del Grupo Enciso (Cretacico Inferior de la cuenca de Cameros, La Rioja): Aplicaciones a la correlacion y datacion de la serie

    Energy Technology Data Exchange (ETDEWEB)

    Angulo, A.; Munoz, A.

    2013-06-01

    We have characterized seven facies linked to three sedimentary environments: distal riverine, siliciclastic lacustrine and carbonate lacustrine, in the Lower Cretaceous syn-rift deposits in the Cameros basin (Enciso Group). The analysis was conducted on a 996-metre-thick series consisting of 74 sedimentary cycles. The facies were analysed using the Markov chains method. We identified three type-sequences linked to the recognised sedimentary environments. By studying the relationships between the facies we were able to develop a sedimentological model, with the relative position of each facies related to the lake shoreline. From this model we could construct a time series based on semi-quantitative depth (depth rank) and analyse it with the Wavelet and REDFIT programs. Spectral analysis identified periodic sedimentary cycles comparable to Milankovitch frequencies. The results show power-spectrum maxima (confidence level >99%) at 90.56 m, 16.66 m, 7.14 m, 5.37 m and 3.93 m. The sedimentary cycle interpreted as short eccentricity (16.66 m) is the most easily identifiable in the outcrop and constitutes the basis of our sequential analysis. The accumulation rate calculated for the Enciso Group is 175 m/Ma. Sedimentation of the Enciso Group at the Munilla section covers a time span of about 6 Ma, from the Upper Hauterivian to the the Middle Aptian. (Author)

  14. The synthesis, design and applications of lanthanide cored complexes

    Science.gov (United States)

    Phelan, Gregory David

    Novel luminescent materials based on lanthanide cored complexes have been designed and synthesized. The complexes consist of a beta-diketone ligand chelated to a lanthanide metal such as europium or gadolinium. A series of beta-diketone ligands were designed and synthesized. The ligands consist of a polycyclic aromatic sensitizer, phenanthrene, and a second functional group. The second groups consisted of another unit of phenanthrene, a dendritic structure, or a fluorinated alkyl chain. The europium complexes have been incorporated into organic light emitting devices that have a major emission at 615 nm and a maximum brightness of 300 cd/m2. The gadolinium complexes were used to dope into the resulting organic light emitting devices to help improve the efficiency of the device. The use of the gadolinium complexes results in a 25 fold increase in efficiency.

  15. k-core covers and the core

    NARCIS (Netherlands)

    Sanchez-Rodriguez, E.; Borm, Peter; Estevez-Fernandez, A.; Fiestras-Janeiro, G.; Mosquera, M.A.

    2015-01-01

    This paper extends the notion of individual minimal rights for a transferable utility game (TU-game) to coalitional minimal rights using minimal balanced families of a specific type, thus defining a corresponding minimal rights game. It is shown that the core of a TU-game coincides with the core of

  16. Academic Rigor: The Core of the Core

    Science.gov (United States)

    Brunner, Judy

    2013-01-01

    Some educators see the Common Core State Standards as reason for stress, most recognize the positive possibilities associated with them and are willing to make the professional commitment to implementing them so that academic rigor for all students will increase. But business leaders, parents, and the authors of the Common Core are not the only…

  17. k-core covers and the core

    NARCIS (Netherlands)

    Sanchez-Rodriguez, E.; Borm, Peter; Estevez-Fernandez, A.; Fiestras-Janeiro, G.; Mosquera, M.A.

    This paper extends the notion of individual minimal rights for a transferable utility game (TU-game) to coalitional minimal rights using minimal balanced families of a specific type, thus defining a corresponding minimal rights game. It is shown that the core of a TU-game coincides with the core of

  18. Series editorial: Network and Service Management Series

    NARCIS (Netherlands)

    Pavlou, George; Pras, Aiko

    2010-01-01

    This is the ninth issue of the series on Network and Service Management, which is typically published twice a year. It was originally published in April and October, but since last year it is published in July and December. The series provides articles on the latest developments in this well establi

  19. Series editorial: Network and Service Management Series

    NARCIS (Netherlands)

    Pavlou, George; Pras, Aiko

    2011-01-01

    This is the 11th issue of the series on Network and Service Management, which is typically published twice a year. It was originally published in April and October but since last year it is published in July and December. The series provides articles on the latest developments in this well-establish

  20. Tailoring Sandwich Face/Core Interfaces for Improved Damage Tolerance

    DEFF Research Database (Denmark)

    Lundsgaard-Larsen, Christian; Berggreen, Christian; Carlsson, Leif A.

    2010-01-01

    Various modifications of the face/core interface in foam core sandwich specimens are examined in a series of two papers. This paper constitutes part I and describes the finite element analysis of a sandwich test specimen, i.e. a DCB specimen loaded by uneven bending moments (DCB-UBM). Using...

  1. A European core curriculum in cariology: the knowledge base

    NARCIS (Netherlands)

    Anderson, P.; Beeley, J.; Monteiro, P.M.; de Soet, H.; Andrian, S.; Amaechi, B.; Huysmans, M.C.D.N.J.M.

    2011-01-01

    This paper is part of a series of papers towards a European Core Curriculum in Cariology for undergraduate dental students. The European Core Curriculum in Cariology is the outcome of a joint workshop of the European Organization for Caries Research (ORCA) together with the Association for Dental Ed

  2. Core-Plus Mathematics. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2010

    2010-01-01

    "Core-Plus Mathematics" is a four-year curriculum that replaces the traditional sequence with courses that each feature interwoven strands of algebra and functions, statistics and probability, geometry and trigonometry, and discrete mathematics. The first three courses in the series provide a common core of broadly useful mathematics,…

  3. Strategic Enrollment Management: Core Strategies and Best Practices

    Science.gov (United States)

    Bontrager, Bob

    2004-01-01

    This second of a two-part series builds on the core concepts and structural considerations discussed in the first part (in the Winter 2004 issue of "College and University") to identify the core strategies and best practices that characterize successful enrollment management (SEM) organizations. Successful SEM operations place a high premium on…

  4. Comodules over semiperfect corings

    CERN Document Server

    Caenepeel, S

    2011-01-01

    We discuss when the Rat functor associated to a coring satisfying the left $\\alpha$-condition is exact. We study the category of comodules over a semiperfect coring. We characterize semiperfect corings over artinian rings and over qF-rings.

  5. Coring Sample Acquisition Tool

    Science.gov (United States)

    Haddad, Nicolas E.; Murray, Saben D.; Walkemeyer, Phillip E.; Badescu, Mircea; Sherrit, Stewart; Bao, Xiaoqi; Kriechbaum, Kristopher L.; Richardson, Megan; Klein, Kerry J.

    2012-01-01

    A sample acquisition tool (SAT) has been developed that can be used autonomously to sample drill and capture rock cores. The tool is designed to accommodate core transfer using a sample tube to the IMSAH (integrated Mars sample acquisition and handling) SHEC (sample handling, encapsulation, and containerization) without ever touching the pristine core sample in the transfer process.

  6. Banded transformer cores

    Science.gov (United States)

    Mclyman, C. W. T. (Inventor)

    1974-01-01

    A banded transformer core formed by positioning a pair of mated, similar core halves on a supporting pedestal. The core halves are encircled with a strap, selectively applying tension whereby a compressive force is applied to the core edge for reducing the innate air gap. A dc magnetic field is employed in supporting the core halves during initial phases of the banding operation, while an ac magnetic field subsequently is employed for detecting dimension changes occurring in the air gaps as tension is applied to the strap.

  7. A Review of Subsequence Time Series Clustering

    Science.gov (United States)

    Teh, Ying Wah

    2014-01-01

    Clustering of subsequence time series remains an open issue in time series clustering. Subsequence time series clustering is used in different fields, such as e-commerce, outlier detection, speech recognition, biological systems, DNA recognition, and text mining. One of the useful fields in the domain of subsequence time series clustering is pattern recognition. To improve this field, a sequence of time series data is used. This paper reviews some definitions and backgrounds related to subsequence time series clustering. The categorization of the literature reviews is divided into three groups: preproof, interproof, and postproof period. Moreover, various state-of-the-art approaches in performing subsequence time series clustering are discussed under each of the following categories. The strengths and weaknesses of the employed methods are evaluated as potential issues for future studies. PMID:25140332

  8. Assessing Stationarity in Ice Core Record-Sea Level Pressure Relationships for Yukon Territory Ice Core Records

    Science.gov (United States)

    Kelsey, E. P.; Wake, C. P.; Osterberg, E. C.

    2014-12-01

    We assess the stationarity of the relationship between Northern Hemisphere winter (Dec-Feb) sea-level pressure (SLP) and proxy time series (major ions, accumulation, and stable isotopes) from the Eclipse (3017 m asl) and the Mt. Logan Prospector-Russell Col (PRCol; 5340 m asl) ice cores from Yukon, Canada. We develop a novel spatial calibration procedure to identify ranges of ice core values that are associated with consistent winter SLP anomaly patterns. Each ice core variable time series was ranked and divided into groups of 13 years each. We assess stationarity by splitting the 1872-2001 analysis period in half (1872-1936 and 1937-2001) and comparing the locations and magnitudes of SLP anomaly patterns during the two periods for each group of ice core values. Northern Hemisphere monthly mean SLP from the 20th Century Reanalysis dataset are used. The high accumulation rate (1.38 m a-1) at Eclipse allows us to analyze 6-month seasonal mean values (Oct-Mar and Apr-Sep), whereas annual mean values are used from PRCol where the accumulation rate is lower (0.40 m a-1). The Eclipse cold season accumulation and PRCol annual mean sodium concentrations (Na+) exhibit the strongest correlations with winter SLP anomaly patterns. In particular, the lowest and highest 20% annual Na+ values at PRCol and lowest 10% cold season accumulation values at Eclipse exhibit stationarity with consistent SLP anomaly patterns in the North Pacific for all three time periods. A weaker Aleutian Low consistently occurred in the central to eastern North Pacific for the lowest Na+ years at PRCol and lowest accumulation cold seasons at Eclipse, although these groups of years are mostly independent. A stronger Aleutian Low occurs in the North Pacific for the highest Na+ years at PRCol. A stationary SLP anomaly pattern is not observed through all three time periods for high cold season accumulation at Eclipse. Application of this calibration procedure with other traditional calibration and

  9. Preparation and characterization of PDMS/PMMA core-shell latex particles having functional group in surface layer%表层功能化PDMS/PMMA核壳乳胶粒子的制备与表征

    Institute of Scientific and Technical Information of China (English)

    张国青; 刘喜军

    2014-01-01

    In this paper, the polydimethyl siloxane/polymethyl methacrylate(PDMS/PMMA)core-shell latex particles (-320 nm)respectively with itaconic acid(ITA),maleic anhydride(MAH)and glycidyl methacrylate(GMA) as functional monomer in surface layer were successfully synthesized employing pre-emulsification semi-continuous process by seeded emulsion polymerization method. Octamethyl cyclotetrasiloxane(D 4 )and Tetravinyl tetramethyl cyelotetrasiloxane as the main monomer were compounded to form PDMS core latex particles with methyl triethoxysilane(MTES)as cross-linking agent. The effects of the reaction time, surfactant and catalyst concentration, and the ratio of D 4 and VD 4 on the polymerization system were studied, and the optimal synthesizing process of PDMS core latex particles was defined.By laser particle size analyzer, Fourier transform infrared spectrometer and transmission electron microscopy analysis showed that the core monomer conversion was nearly 85%and PDMS latex particle size was at about 290 nm when the reaction time was 10 h,surfactant concentration was 5.3%, catalyst concentration was 5.3%,and D4∶VD4=4∶1.%分别以衣康酸(ITA)、马来酸酐(MAH)和甲基丙烯酸缩水甘油酯(GMA)为功能单体,采用预乳化半连续工艺通过种子乳液聚合方法成功合成了表层功能化的聚二甲基硅氧烷/聚甲基丙烯酸甲酯(PDMS/PMMA)核壳乳胶粒子(~320 nm)。PDMS核乳胶粒子以八甲基环四硅氧烷(D 4)和四甲基四乙烯基环四硅氧烷(VD 4)为单体、甲基三乙氧基硅烷(MTES)为交联剂构建而成,实验研究了反应时间、乳化剂和催化剂用量、单体D 4与VD 4比例对聚合体系的影响,并确定了PDMS核乳胶粒子合成最佳工艺。通过激光粒度分析仪、傅里叶变换红外光谱仪、透射电子显微镜等分析表明:当反应时间为10 h、乳化剂用量为核单体总量的5.3%、催化剂用量为核单体总量的5.3%

  10. Time series analysis.

    NARCIS (Netherlands)

    2013-01-01

    Time series analysis can be used to quantitatively monitor, describe, explain, and predict road safety developments. Time series analysis techniques offer the possibility of quantitatively modelling road safety developments in such a way that the dependencies between the observations of time series

  11. Graded core/shell semiconductor nanorods and nanorod barcodes

    Science.gov (United States)

    Alivisatos, A. Paul; Scher, Erik C.; Manna, Liberato

    2010-12-14

    Graded core/shell semiconductor nanorods and shaped nanorods are disclosed comprising Group II-VI, Group III-V and Group IV semiconductors and methods of making the same. Also disclosed are nanorod barcodes using core/shell nanorods where the core is a semiconductor or metal material, and with or without a shell. Methods of labeling analytes using the nanorod barcodes are also disclosed.

  12. Differential Effects on Student Demographic Groups of Using ACT® College Readiness Assessment Composite Score, Act Benchmarks, and High School Grade Point Average for Predicting Long-Term College Success through Degree Completion. ACT Research Report Series, 2013 (5)

    Science.gov (United States)

    Radunzel, Justine; Noble, Julie

    2013-01-01

    In this study, we evaluated the differential effects on racial/ethnic, family income, and gender groups of using ACT® College Readiness Assessment Composite score and high school grade point average (HSGPA) for predicting long-term college success. Outcomes included annual progress towards a degree (based on cumulative credit-bearing hours…

  13. The core paradox.

    Science.gov (United States)

    Kennedy, G. C.; Higgins, G. H.

    1973-01-01

    Rebuttal of suggestions from various critics attempting to provide an escape from the seeming paradox originated by Higgins and Kennedy's (1971) proposed possibility that the liquid in the outer core was thermally stably stratified and that this stratification might prove a powerful inhibitor to circulation of the outer core fluid of the kind postulated for the generation of the earth's magnetic field. These suggestions are examined and shown to provide no reasonable escape from the core paradox.

  14. K-core inflation

    OpenAIRE

    Alexander L. Wolman

    2011-01-01

    K-core inflation is a new class of underlying inflation measures. The two most popular measures of underlying inflation are core inflation and trimmed mean inflation. The former removes fixed categories of goods and services (food and energy) from the inflation calculation, and the latter removes fixed percentiles of the weighted distribution of price changes. In contrast, k-core inflation specifies a size of relative price change to be removed from the inflation calculation. Thus, the catego...

  15. A compact and realistic cerebral cortical layout derived from prewhitened resting-state fMRI time series: Cherniak’s adjacency rule, size law and metamodule grouping upheld

    Directory of Open Access Journals (Sweden)

    Scott M Lewis

    2012-09-01

    Full Text Available We used hierarchical tree clustering to derive a functional organizational chart of 52 human cortical areas (26 per hemisphere from zero-lag correlations calculated between single-voxel, prewhitened, resting-state BOLD fMRI time series in 18 subjects. No special resting-state networks were identified. There were four major features in the resulting tree (dendrogram. First, there was a strong clustering of homotopic, left-right hemispheric areas. Second, cortical areas were concatenated in multiple, partially overlapping clusters. Third, the arrangement of the areas revealed a layout that closely resembled the actual layout of the cerebral cortex, namely an orderly progression from anterior to posterior. And fourth, the layout of the cortical areas in the tree conformed to principles of efficient, compact layout of components proposed by Cherniak. Since the tree was derived on the basis of the strength of neural correlations, these results document an orderly relation between functional interactions and layout, i.e. between structure and function.

  16. Nuclear reactor core modelling in multifunctional simulators

    Energy Technology Data Exchange (ETDEWEB)

    Puska, E.K. [VTT Energy, Nuclear Energy, Espoo (Finland)

    1999-06-01

    The thesis concentrates on the development of nuclear reactor core models for the APROS multifunctional simulation environment and the use of the core models in various kinds of applications. The work was started in 1986 as a part of the development of the entire APROS simulation system. The aim was to create core models that would serve in a reliable manner in an interactive, modular and multifunctional simulator/plant analyser environment. One-dimensional and three-dimensional core neutronics models have been developed. Both models have two energy groups and six delayed neutron groups. The three-dimensional finite difference type core model is able to describe both BWR- and PWR-type cores with quadratic fuel assemblies and VVER-type cores with hexagonal fuel assemblies. The one- and three-dimensional core neutronics models can be connected with the homogeneous, the five-equation or the six-equation thermal hydraulic models of APROS. The key feature of APROS is that the same physical models can be used in various applications. The nuclear reactor core models of APROS have been built in such a manner that the same models can be used in simulator and plant analyser applications, as well as in safety analysis. In the APROS environment the user can select the number of flow channels in the three-dimensional reactor core and either the homogeneous, the five- or the six-equation thermal hydraulic model for these channels. The thermal hydraulic model and the number of flow channels have a decisive effect on the calculation time of the three-dimensional core model and thus, at present, these particular selections make the major difference between a safety analysis core model and a training simulator core model. The emphasis on this thesis is on the three-dimensional core model and its capability to analyse symmetric and asymmetric events in the core. The factors affecting the calculation times of various three-dimensional BWR, PWR and WWER-type APROS core models have been

  17. One Health Core Competency Domains.

    Science.gov (United States)

    Frankson, Rebekah; Hueston, William; Christian, Kira; Olson, Debra; Lee, Mary; Valeri, Linda; Hyatt, Raymond; Annelli, Joseph; Rubin, Carol

    2016-01-01

    The emergence of complex global challenges at the convergence of human, animal, and environmental health has catalyzed a movement supporting "One Health" approaches. Despite recognition of the importance of One Health approaches to address these complex challenges, little effort has been directed at identifying the seminal knowledge, skills, and attitudes necessary for individuals to successfully contribute to One Health efforts. Between 2008 and 2011, three groups independently embarked on separate initiatives to identify core competencies for professionals involved with One Health approaches. Core competencies were considered critically important for guiding curriculum development and continuing professional education, as they describe the knowledge, skills, and attitudes required to be effective. A workshop was convened in 2012 to synthesize the various strands of work on One Health competencies. Despite having different mandates, participants, and approaches, all of these initiatives identified similar core competency domains: management; communication and informatics; values and ethics; leadership; teams and collaboration; roles and responsibilities; and systems thinking. These core competency domains have been used to develop new continuing professional education programs for One Health professionals and help university curricula prepare new graduates to be able to contribute more effectively to One Health approaches.

  18. One Health Core Competency Domains

    Science.gov (United States)

    Frankson, Rebekah; Hueston, William; Christian, Kira; Olson, Debra; Lee, Mary; Valeri, Linda; Hyatt, Raymond; Annelli, Joseph; Rubin, Carol

    2016-01-01

    The emergence of complex global challenges at the convergence of human, animal, and environmental health has catalyzed a movement supporting “One Health” approaches. Despite recognition of the importance of One Health approaches to address these complex challenges, little effort has been directed at identifying the seminal knowledge, skills, and attitudes necessary for individuals to successfully contribute to One Health efforts. Between 2008 and 2011, three groups independently embarked on separate initiatives to identify core competencies for professionals involved with One Health approaches. Core competencies were considered critically important for guiding curriculum development and continuing professional education, as they describe the knowledge, skills, and attitudes required to be effective. A workshop was convened in 2012 to synthesize the various strands of work on One Health competencies. Despite having different mandates, participants, and approaches, all of these initiatives identified similar core competency domains: management; communication and informatics; values and ethics; leadership; teams and collaboration; roles and responsibilities; and systems thinking. These core competency domains have been used to develop new continuing professional education programs for One Health professionals and help university curricula prepare new graduates to be able to contribute more effectively to One Health approaches. PMID:27679794

  19. One Health Core Competency Domains

    Directory of Open Access Journals (Sweden)

    Rebekah Frankson

    2016-09-01

    Full Text Available The emergence of complex global challenges at the convergence of human, animal, and environmental health has catalyzed a movement supporting ‘One Health’ approaches. Despite recognition of the importance of One Health approaches to address these complex challenges, little effort has been directed at identifying the seminal knowledge, skills and attitudes necessary for individuals to successfully contribute to One Health efforts. Between 2008 and 2011, three groups independently embarked on separate initiatives to identify core competencies for professionals involved with One Health approaches. Core competencies were considered critically important for guiding curriculum development and continuing professional education as they describe the knowledge, skills and attitudes required to be effective. A workshop was convened in 2012 to synthesize the various strands of work on One Health competencies. Despite having different mandates, participants, and approaches, all of these initiatives identified similar core competency domains: management; communication and informatics; values and ethics; leadership; teams and collaboration; roles and responsibilities; and systems thinking. These core competency domains have been used to develop new continuing professional education programs for One Health professionals and help university curricula prepare new graduates to be able to contribute more effectively to One Health approaches.

  20. Sediment Core Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides instrumentation and expertise for physical and geoacoustic characterization of marine sediments. DESCRIPTION: The multisensor core logger measures...

  1. Sediment Core Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides instrumentation and expertise for physical and geoacoustic characterization of marine sediments.DESCRIPTION: The multisensor core logger measures...

  2. Core and Valence Structures in K beta X-ray Emission Spectra of Chromium Materials

    NARCIS (Netherlands)

    Torres Deluigi, Maria; de Groot, Frank M. F.|info:eu-repo/dai/nl/08747610X; Lopez-Diaz, Gaston; Tirao, German; Stutz, Guillermo; Riveros de la Vega, Jose

    2014-01-01

    We analyze the core and valence transitions in chromium in a series of materials with a number of different ligands and including the oxidation states: Cr-II, Cr-III, Cr-IV, and Cr-VI. To study the core-to-core transitions we employ the CTM4XAS program and investigate the shapes, widths,

  3. Paleomagnetic correlation of surface and subsurface basaltic lava flows and flow groups in the southern part of the Idaho National Laboratory, Idaho, with paleomagnetic data tables for drill cores

    Science.gov (United States)

    Champion, Duane E.; Hodges, Mary K.V.; Davis, Linda C.; Lanphere, Marvin A.

    2011-01-01

    Paleomagnetic inclination and polarity studies have been conducted on thousands of subcore samples from 51 coreholes located at and near the Idaho National Laboratory. These studies are used to paleomagnetically characterize and correlate successive stratigraphic intervals in each corehole to similar depth intervals in adjacent coreholes. Paleomagnetic results from 83 surface paleomagnetic sites, within and near the INL, are used to correlate these buried lava flow groups to basaltic shield volcanoes still exposed on the surface of the eastern Snake River Plain. Sample handling and demagnetization protocols are described as well as the paleomagnetic data averaging process. Paleomagnetic inclination comparisons between coreholes located only kilometers apart show comparable stratigraphic successions of mean inclination values over tens of meters of depth. At greater distance between coreholes, comparable correlation of mean inclination values is less consistent because flow groups may be missing or additional flow groups may be present and found at different depth intervals. Two shallow intersecting cross-sections, A-A- and B-B- (oriented southwest-northeast and northwest-southeast, respectively), drawn through southwest Idaho National Laboratory coreholes show the corehole to corehole or surface to corehole correlations derived from the paleomagnetic inclination data. From stratigraphic top to bottom, key results included the (1) Quaking Aspen Butte flow group, which erupted from Quaking Aspen Butte southwest of the Idaho National Laboratory, flowed northeast, and has been found in the subsurface in corehole USGS 132; (2) Vent 5206 flow group, which erupted near the southwestern border of the Idaho National Laboratory, flowed north and east, and has been found in the subsurface in coreholes USGS 132, USGS 129, USGS 131, USGS 127, USGS 130, USGS 128, and STF-AQ-01; and (3) Mid Butte flow group, which erupted north of U.S. Highway 20, flowed northwest, and has been

  4. The solar core as never seen before

    Energy Technology Data Exchange (ETDEWEB)

    Eff-Darwich, A; Korzennik, S G, E-mail: adarwich@iac.es, E-mail: skorzennik@cfa.harvard.edu [Instituto de Astrofisica de Canarias (IAC), E-38200 La Laguna, Tenerife (Spain); Department de Edafologia y Geologia, Universidad de La Laguna (ULL), E-38206 La Laguna, Tenerife (Spain); Harvard-Smithsonian Center for Astrophysics, 60 Garden St. Cambridge, MA, 02138 (United States)

    2011-01-01

    One of the main drawbacks in the analysis of the dynamics of the solar core comes from the lack of consistent data sets that cover the low and intermediate degree range (l = 1,200). It is usually necessary to merge data obtained from different instruments and/or fitting methodologies and hence one introduces undesired systematic errors. In contrast, we present the results of analyzing MDI rotational splittings derived by a single fitting methodology applied to 4608-, 2304-, etc..., down to 182-day long time series. The direct comparison of these data sets and the analysis of the numerical inversion results have allowed us to constrain the dynamics of the solar core and to establish the accuracy of these data as a function of the length of the time-series.

  5. Accumulation in Dasuopu ice core in Qinghai-Tibet Plateau and solar activity

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The time series of accumulation in recent 300 years correlated well with solar activity in Dasuopu ice core. Results of spectrum analysis on the accumulation time series of the Dasuopu ice core shows that there are some periods that coincide with the periods of solar activity. By comparing the long-time change trend of the accumulation in the Dasuopu ice core with various kinds of indexes of solar activity intensity, a negative correlation is found between the trend and solar activity.

  6. Fourier Series Operating Package

    Science.gov (United States)

    Charnow, Milton L.

    1961-01-01

    This report presents a computer program for multiplying, adding, differentiating, integrating, "barring" and scalarly multiplying "literal" Fourier series as such, and for extracting the coefficients of specified terms.

  7. Ice Core Investigations

    Science.gov (United States)

    Krim, Jessica; Brody, Michael

    2008-01-01

    What can glaciers tell us about volcanoes and atmospheric conditions? How does this information relate to our understanding of climate change? Ice Core Investigations is an original and innovative activity that explores these types of questions. It brings together popular science issues such as research, climate change, ice core drilling, and air…

  8. Making an Ice Core.

    Science.gov (United States)

    Kopaska-Merkel, David C.

    1995-01-01

    Explains an activity in which students construct a simulated ice core. Materials required include only a freezer, food coloring, a bottle, and water. This hands-on exercise demonstrates how a glacier is formed, how ice cores are studied, and the nature of precision and accuracy in measurement. Suitable for grades three through eight. (Author/PVD)

  9. Ice Core Investigations

    Science.gov (United States)

    Krim, Jessica; Brody, Michael

    2008-01-01

    What can glaciers tell us about volcanoes and atmospheric conditions? How does this information relate to our understanding of climate change? Ice Core Investigations is an original and innovative activity that explores these types of questions. It brings together popular science issues such as research, climate change, ice core drilling, and air…

  10. Iowa Core Annual Report

    Science.gov (United States)

    Iowa Department of Education, 2015

    2015-01-01

    One central component of a great school system is a clear set of expectations, or standards, that educators help all students reach. In Iowa, that effort is known as the Iowa Core. The Iowa Core represents the statewide academic standards, which describe what students should know and be able to do in math, science, English language arts, and…

  11. Mercury's core evolution

    Science.gov (United States)

    Deproost, Marie-Hélène; Rivoldini, Attilio; Van Hoolst, Tim

    2016-10-01

    Remote sensing data of Mercury's surface by MESSENGER indicate that Mercury formed under reducing conditions. As a consequence, silicon is likely the main light element in the core together with a possible small fraction of sulfur. Compared to sulfur, which does almost not partition into solid iron at Mercury's core conditions and strongly decreases the melting temperature, silicon partitions almost equally well between solid and liquid iron and is not very effective at reducing the melting temperature of iron. Silicon as the major light element constituent instead of sulfur therefore implies a significantly higher core liquidus temperature and a decrease in the vigor of compositional convection generated by the release of light elements upon inner core formation.Due to the immiscibility in liquid Fe-Si-S at low pressure (below 15 GPa), the core might also not be homogeneous and consist of an inner S-poor Fe-Si core below a thinner Si-poor Fe-S layer. Here, we study the consequences of a silicon-rich core and the effect of the blanketing Fe-S layer on the thermal evolution of Mercury's core and on the generation of a magnetic field.

  12. Mars' core and magnetism.

    Science.gov (United States)

    Stevenson, D J

    2001-07-12

    The detection of strongly magnetized ancient crust on Mars is one of the most surprising outcomes of recent Mars exploration, and provides important insight about the history and nature of the martian core. The iron-rich core probably formed during the hot accretion of Mars approximately 4.5 billion years ago and subsequently cooled at a rate dictated by the overlying mantle. A core dynamo operated much like Earth's current dynamo, but was probably limited in duration to several hundred million years. The early demise of the dynamo could have arisen through a change in the cooling rate of the mantle, or even a switch in convective style that led to mantle heating. Presently, Mars probably has a liquid, conductive outer core and might have a solid inner core like Earth.

  13. Exploring Cosmic Origins with CORE: Cosmological Parameters

    CERN Document Server

    Di Valentino, Eleonora; Gerbino, Martina; Poulin, Vivian; Bouchet, François R; Lesgourgues, Julien; Melchiorri, Alessandro; Chluba, Jens; Clesse, Sebastien; Delabrouille, Jacques; Dvorkin, Cora; Forastieri, Francesco; Galli, Silvia; Hooper, Deanna C; Lattanzi, Massimiliano; Martins, Carlos J A P; Salvati, Laura; Cabass, Giovanni; Caputo, Andrea; Giusarma, Elena; Hivon, Eric; Natoli, Paolo; Pagano, Luca; Paradiso, Simone; Rubino-Martin, Jose Alberto; Achucarro, Ana; Ballardini, Mario; Bartolo, Nicola; Baumann, Daniel; Bartlett, James G; de Bernardis, Paolo; Bonaldi, Anna; Bucher, Martin; Cai, Zhen-Yi; De Zotti, Gianfranco; Diego, Josè Maria; Errard, Josquin; Ferraro, Simone; Finelli, Fabio; Genova-Santos, Ricardo T; Gonzalez-Nuevo, Joaquin; Grandis, Sebastian; Greenslade, Josh; Hagstotz, Steffen; Handley, Will; Hindmarsh, Mark; Hernandez-Monteagudo, Carlos; Kiiveri, Kimmo; Kunz, Martin; Lasenby, Anthony; Liguori, Michele; Lopez-Caniego, Marcos; Luzzi, Gemma; Melin, Jean-Baptiste; Mohr, Joseph J; Negrello, Mattia; Paoletti, Daniela; Remazeilles, Mathieu; Ringeval, Christophe; Valiviita, Jussi; Van Tent, Bartjan; Vennin, Vincent; Vittorio, Nicola

    2016-01-01

    We forecast the main cosmological parameter constraints achievable with the CORE space mission which is dedicated to mapping the polarisation of the Cosmic Microwave Background (CMB). CORE was recently submitted in response to ESA's fifth call for medium-sized mission proposals (M5). Here we report the results from our pre-submission study of the impact of various instrumental options, in particular the telescope size and sensitivity level, and review the great, transformative potential of the mission as proposed. Specifically, we assess the impact on a broad range of fundamental parameters of our Universe as a function of the expected CMB characteristics, with other papers in the series focusing on controlling astrophysical and instrumental residual systematics. In this paper, we assume that only a few central CORE frequency channels are usable for our purpose, all others being devoted to the cleaning of astrophysical contaminants. On the theoretical side, we assume LCDM as our general framework and quantify...

  14. Mutagenicity in a Molecule: Identification of Core Structural Features of Mutagenicity Using a Scaffold Analysis.

    Directory of Open Access Journals (Sweden)

    Kuo-Hsiang Hsu

    Full Text Available With advances in the development and application of Ames mutagenicity in silico prediction tools, the International Conference on Harmonisation (ICH has amended its M7 guideline to reflect the use of such prediction models for the detection of mutagenic activity in early drug safety evaluation processes. Since current Ames mutagenicity prediction tools only focus on functional group alerts or side chain modifications of an analog series, these tools are unable to identify mutagenicity derived from core structures or specific scaffolds of a compound. In this study, a large collection of 6512 compounds are used to perform scaffold tree analysis. By relating different scaffolds on constructed scaffold trees with Ames mutagenicity, four major and one minor novel mutagenic groups of scaffold are identified. The recognized mutagenic groups of scaffold can serve as a guide for medicinal chemists to prevent the development of potentially mutagenic therapeutic agents in early drug design or development phases, by modifying the core structures of mutagenic compounds to form non-mutagenic compounds. In addition, five series of substructures are provided as recommendations, for direct modification of potentially mutagenic scaffolds to decrease associated mutagenic activities.

  15. Korrelasjon mellom core styrke, core stabilitet og utholdende styrke i core

    OpenAIRE

    Berg-Olsen, Andrea Marie; Fugelsøy, Eivor; Maurstad, Ann-Louise

    2010-01-01

    Formålet med studien var å se hvilke korrelasjon det er mellom core styrke, core stabilitet og utholdende styrke i core. Testingen bestod av tre hoveddeler hvor vi testet core styrke, core stabilitet og utholdende styrke i core. Innenfor core styrke og utholdende styrke i core ble tre ulike tester utført. Ved måling av core stabilitet ble det gjennomført kun en test. I core styrke ble isometrisk abdominal fleksjon, isometrisk rygg ekstensjon og isometrisk lateral fleksjon testet. Sit-ups p...

  16. Korrelasjon mellom core styrke, core stabilitet og utholdende styrke i core

    OpenAIRE

    Berg-Olsen, Andrea Marie; Fugelsøy, Eivor; Maurstad, Ann-Louise

    2010-01-01

    Formålet med studien var å se hvilke korrelasjon det er mellom core styrke, core stabilitet og utholdende styrke i core. Testingen bestod av tre hoveddeler hvor vi testet core styrke, core stabilitet og utholdende styrke i core. Innenfor core styrke og utholdende styrke i core ble tre ulike tester utført. Ved måling av core stabilitet ble det gjennomført kun en test. I core styrke ble isometrisk abdominal fleksjon, isometrisk rygg ekstensjon og isometrisk lateral fleksjon testet. Sit-ups p...

  17. Earth's inner core: Innermost inner core or hemispherical variations?

    NARCIS (Netherlands)

    Lythgoe, K. H.; Deuss, A.; Rudge, J. F.; Neufeld, J. A.

    2014-01-01

    The structure of Earth's deep inner core has important implications for core evolution, since it is thought to be related to the early stages of core formation. Previous studies have suggested that there exists an innermost inner core with distinct anisotropy relative to the rest of the inner core.

  18. Earth's inner core: Innermost inner core or hemispherical variations?

    NARCIS (Netherlands)

    Lythgoe, K. H.; Deuss, A.; Rudge, J. F.; Neufeld, J. A.

    2014-01-01

    The structure of Earth's deep inner core has important implications for core evolution, since it is thought to be related to the early stages of core formation. Previous studies have suggested that there exists an innermost inner core with distinct anisotropy relative to the rest of the inner core.

  19. Seri Kinship Terminology.

    Science.gov (United States)

    Moser, Mary B.; Marlett, Stephen A.

    The Seri language contains over 50 kinship terms and represents one of the most highly elaborated kinship systems described to date. This paper discusses Seri kinship terminology and centers around, but is not limited to, the set of obligatory possessed noun stems that are inflected with the following possessive prefixes": "hi-,""ma-," and "a-."…

  20. Time Series Momentum

    DEFF Research Database (Denmark)

    Moskowitz, Tobias J.; Ooi, Yao Hua; Heje Pedersen, Lasse

    2012-01-01

    under-reaction and delayed over-reaction. A diversified portfolio of time series momentum strategies across all asset classes delivers substantial abnormal returns with little exposure to standard asset pricing factors and performs best during extreme markets. Examining the trading activities...... of speculators and hedgers, we find that speculators profit from time series momentum at the expense of hedgers....

  1. Periodic Time Series Models

    NARCIS (Netherlands)

    Ph.H.B.F. Franses (Philip Hans); R. Paap (Richard)

    2004-01-01

    textabstractThis book considers periodic time series models for seasonal data, characterized by parameters that differ across the seasons, and focuses on their usefulness for out-of-sample forecasting. Providing an up-to-date survey of the recent developments in periodic time series, the book

  2. Fourier Series Optimization Opportunity

    Science.gov (United States)

    Winkel, Brian

    2008-01-01

    This note discusses the introduction of Fourier series as an immediate application of optimization of a function of more than one variable. Specifically, it is shown how the study of Fourier series can be motivated to enrich a multivariable calculus class. This is done through discovery learning and use of technology wherein students build the…

  3. AMTEC vapor-vapor series connected cells

    Science.gov (United States)

    Underwood, Mark L.; Williams, Roger M.; Ryan, Margaret A.; Nakamura, Barbara J.; Oconnor, Dennis E.

    1995-08-01

    An alkali metal thermoelectric converter (AMTEC) having a plurality of cells structurally connected in series to form a septum dividing a plenum into two chambers, and electrically connected in series, is provided with porous metal anodes and porous metal cathodes in the cells. The cells may be planar or annular, and in either case a metal alkali vapor at a high temperature is provided to the plenum through one chamber on one side of the wall and returned to a vapor boiler after condensation at a chamber on the other side of the wall in the plenum. If the cells are annular, a heating core may be placed along the axis of the stacked cells. This arrangement of series-connected cells allows efficient generation of power at high voltage and low current.

  4. SERI Wind Energy Program

    Energy Technology Data Exchange (ETDEWEB)

    Noun, R. J.

    1983-06-01

    The SERI Wind Energy Program manages the areas or innovative research, wind systems analysis, and environmental compatibility for the U.S. Department of Energy. Since 1978, SERI wind program staff have conducted in-house aerodynamic and engineering analyses of novel concepts for wind energy conversion and have managed over 20 subcontracts to determine technical feasibility; the most promising of these concepts is the passive blade cyclic pitch control project. In the area of systems analysis, the SERI program has analyzed the impact of intermittent generation on the reliability of electric utility systems using standard utility planning models. SERI has also conducted methodology assessments. Environmental issues related to television interference and acoustic noise from large wind turbines have been addressed. SERI has identified the causes, effects, and potential control of acoustic noise emissions from large wind turbines.

  5. Different strategies in solving series completion inductive reasoning problems : An fMRI and computational study

    NARCIS (Netherlands)

    Liang, Peipeng; Jia, Xiuqin; Taatgen, Niels A.; Zhong, Ning; Li, Kuncheng

    2014-01-01

    Neural correlate of human inductive reasoning process is still unclear. Number series and letter series completion are two typical inductive reasoning tasks, and with a common core component of rule induction. Previous studies have demonstrated that different strategies are adopted in number series

  6. Weaving a Tapestry from Threads Spun by Geneticists: The Series Perspectives on Genetics, 1987-2008.

    Science.gov (United States)

    Dove, William F

    2016-07-01

    The Perspectives column was initiated in 1987 when Jan Drake, Editor-in-Chief of GENETICS, invited Jim Crow and William Dove to serve as coeditors of "Anecdotal, Historical, and Critical Commentaries." As the series evolved over 21 years, under the guidance of Crow and Dove, the input of stories told by geneticists from many countries created a panorama of 20th-century genetics. Three recurrent themes are visible: how geneticists have created the science (as solitary investigators, in pairs, or in cooperative groups); how geneticists work hard, but find ways to have fun; and how public and private institutions have sustained the science of genetics, particularly in the United States. This article ends by considering how the Perspectives series and other communication formats can carry forward the core science of genetics from the 20th into the 21st century.

  7. Combining nutation and surface gravity observations to estimate the Earth's core and inner core resonant frequencies

    Science.gov (United States)

    Ziegler, Yann; Lambert, Sébastien; Rosat, Séverine; Nurul Huda, Ibnu; Bizouard, Christian

    2017-04-01

    Nutation time series derived from very long baseline interferometry (VLBI) and time varying surface gravity data recorded by superconducting gravimeters (SG) have long been used separately to assess the Earth's interior via the estimation of the free core and inner core resonance effects on nutation or tidal gravity. The results obtained from these two techniques have been shown recently to be consistent, making relevant the combination of VLBI and SG observables and the estimation of Earth's interior parameters in a single inversion. We present here the intermediate results of the ongoing project of combining nutation and surface gravity time series to improve estimates of the Earth's core and inner core resonant frequencies. We use VLBI nutation time series spanning 1984-2016 derived by the International VLBI Service for geodesy and astrometry (IVS) as the result of a combination of inputs from various IVS analysis centers, and surface gravity data from about 15 SG stations. We address here the resonance model used for describing the Earth's interior response to tidal excitation, the data preparation consisting of the error recalibration and amplitude fitting for nutation data, and processing of SG time-varying gravity to remove any gaps, spikes, steps and other disturbances, followed by the tidal analysis with the ETERNA 3.4 software package, the preliminary estimates of the resonant periods, and the correlations between parameters.

  8. Glass-clad semiconductor core optical fibers

    Science.gov (United States)

    Morris, Stephanie Lynn

    Glass-clad optical fibers comprising a crystalline semiconductor core have garnered considerable recent attention for their potential utility as novel waveguides for applications in nonlinear optics, sensing, power delivery, and biomedicine. As research into these fibers has progressed, it has become evident that excessive losses are limiting performance and so greater understanding of the underlying materials science, coupled with advances in fiber processing, is needed. More specifically, the semiconductor core fibers possess three performance-limiting characteristics that need to be addressed: (a) thermal expansion mismatches between crystalline core and glass cladding that lead to cracks, (b) the precipitation of oxide species in the core upon fiber cooling, which results from partial dissolution of the cladding glass by the core melt, and (c) polycrystallinity; all of which lead to scattering and increased transmission losses. This dissertation systematically studies each of these effects and develops both a fundamental scientific understanding of and practical engineering methods for reducing their impact. With respect to the thermal expansion mismatch and, in part, the dissolution of oxides, for the first time to our knowledge, oxide and non-oxide glass compositions are developed for a series of semiconductor cores based on two main design criteria: (1) matching the thermal expansion coefficient between semiconductor core and glass cladding to minimize cracking and (2) matching the viscosity-temperature dependences, such that the cladding glass draws into fiber at a temperature slightly above the melting point of the semiconductor in order to minimize dissolution and improve the fiber draw process. The x[Na 2O:Al2O3] + (100 - 2x)SiO2 glass compositional family was selected due to the ability to tailor the glass properties to match the aforementioned targets through slight variations in composition and adjusting the ratios of bridging and non-bridging oxygen

  9. IGCSE core mathematics

    CERN Document Server

    Wall, Terry

    2013-01-01

    Give your core level students the support and framework they require to get their best grades with this book dedicated to the core level content of the revised syllabus and written specifically to ensure a more appropriate pace. This title has been written for Core content of the revised Cambridge IGCSE Mathematics (0580) syllabus for first teaching from 2013. ? Gives students the practice they require to deepen their understanding through plenty of practice questions. ? Consolidates learning with unique digital resources on the CD, included free with every book. We are working with Cambridge

  10. Core shroud corner joints

    Science.gov (United States)

    Gilmore, Charles B.; Forsyth, David R.

    2013-09-10

    A core shroud is provided, which includes a number of planar members, a number of unitary corners, and a number of subassemblies each comprising a combination of the planar members and the unitary corners. Each unitary corner comprises a unitary extrusion including a first planar portion and a second planar portion disposed perpendicularly with respect to the first planar portion. At least one of the subassemblies comprises a plurality of the unitary corners disposed side-by-side in an alternating opposing relationship. A plurality of the subassemblies can be combined to form a quarter perimeter segment of the core shroud. Four quarter perimeter segments join together to form the core shroud.

  11. Biospecimen Core Resource - TCGA

    Science.gov (United States)

    The Cancer Genome Atlas (TCGA) Biospecimen Core Resource centralized laboratory reviews and processes blood and tissue samples and their associated data using optimized standard operating procedures for the entire TCGA Research Network.

  12. NICHD Zebrafish Core

    Data.gov (United States)

    Federal Laboratory Consortium — The core[HTML_REMOVED]s goal is to help researchers of any expertise perform zebrafish experiments aimed at illuminating basic biology and human disease mechanisms,...

  13. iPSC Core

    Data.gov (United States)

    Federal Laboratory Consortium — The induced Pluripotent Stem Cells (iPSC) Core was created in 2011 to accelerate stem cell research in the NHLBI by providing investigators consultation, technical...

  14. Reference: -300CORE [PLACE

    Lifescience Database Archive (English)

    Full Text Available -300CORE Forde BG, Heyworth A, Pywell J, Kreis M Nucleotide sequence of a B1 hordein gene and the identifica...tion of possible upstream regulatory elements in endosperm storage protein genes fr

  15. INTEGRAL core programme

    Science.gov (United States)

    Gehrels, N.; Schoenfelder, V.; Ubertini, P.; Winkler, C.

    1997-01-01

    The International Gamma Ray Astrophysics Laboratory (INTEGRAL) mission is described with emphasis on the INTEGRAL core program. The progress made in the planning activities for the core program is reported on. The INTEGRAL mission has a nominal lifetime of two years with a five year extension option. The observing time will be divided between the core program (between 30 and 35 percent during the first two years) and general observations. The core program consists of three main elements: the deep survey of the Galactic plane in the central radian of the Galaxy; frequent scans of the Galactic plane in the search for transient sources, and pointed observations of several selected sources. The allocation of the observation time is detailed and the sensitivities of the observations are outlined.

  16. Focusing on Core Business

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    China is regulating state-owned enterprises that are investing outside of their core business realms, concerned that poor investment decisions could lead to loss of state-owned assets, but some doubt the effect of the new regulation

  17. Organizing Core Tasks

    DEFF Research Database (Denmark)

    Boll, Karen

    Civil servants conduct the work which makes welfare states functions on an everyday bases: Police men police, school teachers teach, and tax inspectors inspect. Focus in this paper is on the core tasks of tax inspectors. The paper argues that their core task of securing the collection of revenue...... has remained much the same within the last 10 years. However, how the core task has been organized has changed considerable under the influence of various “organizing devices”. The paper focusses on how organizing devices such as risk assessment, output-focus, effect orientation, and treatment...... projects influence the organization of core tasks within the tax administration. The paper shows that the organizational transformations based on the use of these devices have had consequences both for the overall collection of revenue and for the employees’ feeling of “making a difference”. All in all...

  18. Rich-cores in networks

    CERN Document Server

    Ma, Athen

    2014-01-01

    A core is said to be a group of central and densely connected nodes which governs the overall behavior of a network. Profiling this meso--scale structure currently relies on a limited number of methods which are often complex, and have scalability issues when dealing with very large networks. As a result, we are yet to fully understand its impact on network properties and dynamics. Here we introduce a simple method to profile this structure by combining the concepts of core/periphery and rich-club. The key challenge in addressing such association of the two concepts is to establish a way to define the membership of the core. The notion of a "rich-club" describes nodes which are essentially the hub of a network, as they play a dominating role in structural and functional properties. Interestingly, the definition of a rich-club naturally emphasizes high degree nodes and divides a network into two subgroups. Our approach theoretically couples the underlying principle of a rich-club with the escape time of a rand...

  19. The Next Generation Virgo Cluster Survey. VII. The intrinsic shapes of low-luminosity galaxies in the core of the Virgo cluster, and a comparison with the Local Group

    CERN Document Server

    Sanchez-Janssen, R; MacArthur, L A; Cote, P; Blakeslee, J P; Cuillandre, J -C; Duc, P -A; Durrell, P; Gwyn, S; McConnachie, A W; Boselli, A; Courteau, S; Emsellem, E; Mei, S; Peng, E; Puzia, T H; Roediger, J; Simard, L; Boyer, F; Santos, M

    2016-01-01

    (Abridged) We investigate the intrinsic shapes of low-luminosity galaxies in the central 300 kpc of the Virgo cluster using deep imaging obtained as part of the NGVS. We build a sample of nearly 300 red-sequence cluster members in the yet unexplored $-14 < M_{g} < -8$ magnitude range. The observed distribution of apparent axis ratios is then fit by families of triaxial models with normally-distributed intrinsic ellipticities and triaxialities. We develop a Bayesian framework to explore the posterior distribution of the model parameters, which allows us to work directly on discrete data, and to account for individual, surface brightness-dependent axis ratio uncertainties. For this population we infer a mean intrinsic ellipticity E=0.43, and a mean triaxiality T=0.16. This implies that faint Virgo galaxies are best described as a family of thick, nearly oblate spheroids with mean intrinsic axis ratios 1:0.94:0.57. We additionally attempt a study of the intrinsic shapes of Local Group satellites of similar...

  20. Treatment of lower extremity biomechanics correction combined with spinal core muscle groups training for chronic nonspecific low back pain%下肢生物力学矫正联合脊柱区核心肌群训练治疗慢性非特异性下腰痛

    Institute of Scientific and Technical Information of China (English)

    李小金; 韩秀兰; 成守珍

    2014-01-01

    Objective To discuss clinical effects of lower extremity biomechanics correction with spinal core muscle groups training for the treatment of patients with chronic non-specific low back pain (LBP). Methods Thirty-two chronic non-specific LBP patients treated by lower extremity biomechanics correction were randomly divided into observation group and control group, with 16 patients in each group. They were all configured biomechanics orthopedic insole, and treated by conventional physical therapy and manipulation therapy at the same time. In addition, patients in observation group performed spinal core muscle group training. Before and after treatment, pain visual analogue scale (VAS) and LBP Oswestry disability index (ODI) scores in two groups were recorded and compared. Results At 1, 6 months after the treatment, VAS and ODI scores improved, the differences between pre- and post-treatment had statistical significance (P 0.05), while there was statistical difference between two groups after the treatment (P <0.05). Conclusion For non-specific LBP patients, spinal core muscle groups training strengthens the efficacy of lower extremity biomechanics correction, as a result, could relieve lumbar pain and improve the quality of life.%目的:探讨下肢生物力学矫正联合脊柱区核心肌群训练对慢性非特异性下腰痛患者的治疗效果。方法将符合要求并接受下肢生物力学矫正治疗的32例慢性非特异性下腰痛患者随机分为观察组与对照组,每组各16例,两组患者均配置生物力学矫形鞋垫,并进行常规理疗、手法治疗等,观察组患者联合脊柱区核心肌群训练。记录并比较两组患者治疗前后疼痛视觉模拟量表(VAS)评分和腰腿痛Oswestry功能障碍指数(ODI)评分。结果两组患者治疗前VAS、ODI评分比较,差异无统计学意义(P>0.05);治疗后1、6个月VAS评分、ODI评分均有改善,观察组改善较对照组

  1. Historical Climatology Series

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Historical Climatology Series (HCS) is a set of climate-related publications published by NOAA's National Climatic Data Center beginning in 1978. HCS is...

  2. Multivariate Time Series Search

    Data.gov (United States)

    National Aeronautics and Space Administration — Multivariate Time-Series (MTS) are ubiquitous, and are generated in areas as disparate as sensor recordings in aerospace systems, music and video streams, medical...

  3. Long time series

    DEFF Research Database (Denmark)

    Hisdal, H.; Holmqvist, E.; Hyvärinen, V.;

    Awareness that emission of greenhouse gases will raise the global temperature and change the climate has led to studies trying to identify such changes in long-term climate and hydrologic time series. This report, written by the......Awareness that emission of greenhouse gases will raise the global temperature and change the climate has led to studies trying to identify such changes in long-term climate and hydrologic time series. This report, written by the...

  4. Long time series

    DEFF Research Database (Denmark)

    Hisdal, H.; Holmqvist, E.; Hyvärinen, V.

    Awareness that emission of greenhouse gases will raise the global temperature and change the climate has led to studies trying to identify such changes in long-term climate and hydrologic time series. This report, written by the......Awareness that emission of greenhouse gases will raise the global temperature and change the climate has led to studies trying to identify such changes in long-term climate and hydrologic time series. This report, written by the...

  5. 以病例为核心的药学本科生临床见习分组作业教学方案的设计与实施%Design and implementation of a teaching program of clinical probation in groups with case reports as its core for pharmaceutical undergraduates

    Institute of Scientific and Technical Information of China (English)

    王卓; 蔡和平; 黄瑾; 杨黎; 孙华君; 高申

    2012-01-01

    Objective: To present a teaching program of clinical probation in groups with case reports as its core for pharmaceutical undergraduates, and describe the implementation process and results of the program. Methods: With reference to the contents of routine pharmaceutical care by clinical pharmacists and in accordance with the training program of pharmaceutical undergraduates, the teaching program was designed with case reports as its core. At the same time, it was centered round the collection of patient history, the evaluation of pharmaceutical care, the analysis and treatment of drug-related problems, as well as the analysis and implementation of pharmaceutical care. Teaching forms,such as clinical teaching, group practice, written work coupled with oral discussion were organically integrated in the teaching program. Results: As a result, students were very enthusiastic about this teaching method and high scores were achieved in various tests, and there was a unanimously positive response to this teaching mode. Conclusion: It is necessary for pharmaceutical undergraduates to have clinical probation practice. The mode of group practice with the case reports as its core has achieved better teaching results.%目的:提出一种以病例为核心的药学本科生临床见习分组作业的教学方案,并描述其实施过程和实施效果.方法:参照临床药师日常药学服务所含内容,依据药学本科生培养方案,设计以病例教学为核心,围绕病人病史采集、药物治疗方案评价、药物相关问题分析与处理、药学服务的分析与实施等内容,采用临床教学、分组实践,书面作业与口头讨论相结合的教学方法进行.结果:学员学习热情高,考核成绩优良,学员对此教学方式反映积极.结论:药学生临床见习教学有较大的必要性,以病例为核心的分组作业方式具有较好的教学效果.

  6. Comparison of HCV core and coreE1E2 virus-like particles generated by stably transfected Leishmania tarentolae for stimulation of Th1 immune responses in mice.

    Science.gov (United States)

    Bolhassani, Azam; Davoudi, Noushin; Agi, Elnaz; Motevalli, Fatemeh

    2017-01-25

    Virus-like particles (VLPs) could be improved into successful immunogens as well as a potent delivery vehicle, but however, the current expression systems for VLPs production have some limitations. Recently, we developed a novel strategy to produce two HCV VLPs containing core or coreE1E2 proteins using stably transfected Leishmania tarentolae promastigotes. Then, BALB/c mice were injected by both viral like particles in different immunization strategies such as homologous DNA-, homologous VLP-, and heterologous DNA/ VLP-based immunizations. TEM microscopy indicated HCV core and HCV coreE1E2 VLP assembly with average size of 30-40 and 40-60 nm after purification, respectively. Our results showed that homologous immunizations with both HCV core or coreE1E2 VLPs significantly induced anti-core or anti-coreE1E2 antibody responses, respectively as well as secretion of IFN-γ cytokine as compared to other strategies. Moreover, DNA-prime/VLP-boost regimens significantly elicited higher levels of IFN-γ and antibody responses in comparison with homologous DNA/DNA regimens. The groups immunized with homologous or heterologous coreE1E2 VLPs showed markedly higher immune responses as compared to groups immunized with core VLP regimens against coreE1E2 protein. The crude HCV VLPs generated by Leishmania expression system could elicit a Th1-type response as a promising vaccine candidate against HCV infections.

  7. Packing in protein cores

    Science.gov (United States)

    Gaines, J. C.; Clark, A. H.; Regan, L.; O'Hern, C. S.

    2017-07-01

    Proteins are biological polymers that underlie all cellular functions. The first high-resolution protein structures were determined by x-ray crystallography in the 1960s. Since then, there has been continued interest in understanding and predicting protein structure and stability. It is well-established that a large contribution to protein stability originates from the sequestration from solvent of hydrophobic residues in the protein core. How are such hydrophobic residues arranged in the core; how can one best model the packing of these residues, and are residues loosely packed with multiple allowed side chain conformations or densely packed with a single allowed side chain conformation? Here we show that to properly model the packing of residues in protein cores it is essential that amino acids are represented by appropriately calibrated atom sizes, and that hydrogen atoms are explicitly included. We show that protein cores possess a packing fraction of φ ≈ 0.56 , which is significantly less than the typically quoted value of 0.74 obtained using the extended atom representation. We also compare the results for the packing of amino acids in protein cores to results obtained for jammed packings from discrete element simulations of spheres, elongated particles, and composite particles with bumpy surfaces. We show that amino acids in protein cores pack as densely as disordered jammed packings of particles with similar values for the aspect ratio and bumpiness as found for amino acids. Knowing the structural properties of protein cores is of both fundamental and practical importance. Practically, it enables the assessment of changes in the structure and stability of proteins arising from amino acid mutations (such as those identified as a result of the massive human genome sequencing efforts) and the design of new folded, stable proteins and protein-protein interactions with tunable specificity and affinity.

  8. Posn(R) and Eisenstein series

    CERN Document Server

    Jorgenson, Jay

    2005-01-01

    Posn(R) and Eisenstein Series provides an introduction, requiring minimal prerequisites, to the analysis on symmetric spaces of positive definite real matrices as well as quotients of this space by the unimodular group of integral matrices. The approach is presented in very classical terms and includes material on special functions, notably gamma and Bessel functions, and focuses on certain mathematical aspects of Eisenstein series.

  9. Facile Determination of Molecular Structure Trends in Amphiphilic Core Corona Star Polymer Synthesis via Dielectric Property Measurement.

    Science.gov (United States)

    Hild, Frederic; Nguyen, Nam T; Deng, Eileen; Katrib, Juliano; Dimitrakis, Georgios; Lau, Phei-Li; Irvine, Derek J

    2016-08-01

    The use of dielectric property measurements to define specific trends in the molecular structures of poly(caprolactone) containing star polymers and/or the interbatch repeatability of the synthetic procedures used to generate them is demonstrated. The magnitude of the dielectric property value is shown to accurately reflect: (a) the number of functional groups within a series of materials with similar molecular size when no additional intermolecular order is present in the medium, (b) the polymer molecular size for a series of materials containing a fixed core material and so functional group number, and/or (c) the batch to batch repeatability of the synthesis method. The dielectric measurements are validated by comparison to spectroscopic/chromatographic data.

  10. Group Cooperation in Outdoor Education

    Science.gov (United States)

    Matthews, Bruce E.

    1978-01-01

    Utilizing the Beatles' Yellow Submarine fantasy (e.g., the Blue Meanies), this outdoor education program is designed for sixth graders and special education students. Activities developed at the Cortland Resident Outdoor Education Camp include a series of group stress/challenge activities to be accomplished by everyone in the group, as a group.…

  11. 血管源性轻度认知障碍中医核心术语在不同人群中应答情况研究%Research of the Core Terminology of Traditional Chinese Medicine on Vascular Mild Cognitive Impairment for the Response in Different Groups

    Institute of Scientific and Technical Information of China (English)

    薛斐然; 刘文娜; 张允岭; 金香兰; 牛焕敏; 张艳霞; 陈宝鑫; 傅晨; 郑硕; 南一楠

    2013-01-01

    Objective To verify and optimize the core terminology of traditional Chinese medicine on vascular mild cognitive impairment for the response in different groups. Methods By the investigation of the chief complains of the patients and the explanation of the relatives for 945 cases of cognitive impairment, the information was collected on the scene. The chi - square analysis and reliability analysis method were a-dopted to verify and optimize the core terminology of traditional Chinese medicine for vascular mild cognitive impairment. Results Twelve core terms were verified and optimized, including memory loss , misunderstanding" , "absent mind" , " poor behavior" , " disliking speech, word repetition, mis - speaking" , " illogical and poor words , sorrow and worries , disability , keeping away from crowd , disliking movement, somnolence" ,"drowsiness at daytime and restlessness at night". For the term,"suspiciousness and hesitant decision , a further discussion and clinical re - verification was required. Conclusion The twelve core terms better reflect the state of the patients with vascular mild cognitive impairment. All of these terms distinguish from the terminology of dementia and western medicine and can be used for the symptom description.%目的 就不同人群临床应答情况验证、优化血管源性轻度认知障碍中医核心术语.方法 通过对945例有认知障碍主诉或家属代诉患者的调查,现场收集信息,采用卡方分析、信度分析的方法验证、优化血管源性轻度认知障碍中医核心术语.结果 验证并优化出"转盼遗忘""多忘善误""神思不聚""持筹握算差""言语懒、重复、言善误""言辞颠倒、贫乏""忧愁思虑""庶事皆废""居暗避人""思维反应迟钝""懒动嗜卧""日间静则瞌睡、夜间躁扰不宁"12项核心术语,"多疑寡断"需进行进一步论证及临床再验证.结论 12项核心术语能较好的体现血管源性轻度认知障碍患者的状态,所有术语

  12. On Sums of Numerical Series and Fourier Series

    Science.gov (United States)

    Pavao, H. Germano; de Oliveira, E. Capelas

    2008-01-01

    We discuss a class of trigonometric functions whose corresponding Fourier series, on a conveniently chosen interval, can be used to calculate several numerical series. Particular cases are presented and two recent results involving numerical series are recovered. (Contains 1 note.)

  13. Inner core structure behind the PKP core phase triplication

    NARCIS (Netherlands)

    Blom, Nienke A.; Deuss, Arwen; Paulssen, Hanneke; Waszek, Lauren

    2015-01-01

    The structure of the Earth's inner core is not well known between depths of ∼100–200 km beneath the inner core boundary. This is a result of the PKP core phase triplication and the existence of strong precursors to PKP phases, which hinder the measurement of inner core compressional PKIKP waves at e

  14. Inner core structure behind the PKP core phase triplication

    NARCIS (Netherlands)

    Blom, Nienke A.; Deuss, Arwen; Paulssen, Hanneke; Waszek, Lauren

    The structure of the Earth's inner core is not well known between depths of ∼100–200 km beneath the inner core boundary. This is a result of the PKP core phase triplication and the existence of strong precursors to PKP phases, which hinder the measurement of inner core compressional PKIKP waves at

  15. Pressure Core Characterization

    Science.gov (United States)

    Santamarina, J. C.

    2014-12-01

    Natural gas hydrates form under high fluid pressure and low temperature, and are found in permafrost, deep lakes or ocean sediments. Hydrate dissociation by depressurization and/or heating is accompanied by a multifold hydrate volume expansion and host sediments with low permeability experience massive destructuration. Proper characterization requires coring, recovery, manipulation and testing under P-T conditions within the stability field. Pressure core technology allows for the reliable characterization of hydrate bearing sediments within the stability field in order to address scientific and engineering needs, including the measurement of parameters used in hydro-thermo-mechanical analyses, and the monitoring of hydrate dissociation under controlled pressure, temperature, effective stress and chemical conditions. Inherent sampling effects remain and need to be addressed in test protocols and data interpretation. Pressure core technology has been deployed to study hydrate bearing sediments at several locations around the world. In addition to pressure core testing, a comprehensive characterization program should include sediment analysis, testing of reconstituted specimens (with and without synthetic hydrate), and in situ testing. Pressure core characterization technology can be used to study other gas-charged formations such as deep sea sediments, coal bed methane and gas shales.

  16. Focus group discussions

    CERN Document Server

    Hennink, Monique M

    2014-01-01

    The Understanding Research series focuses on the process of writing up social research. The series is broken down into three categories: Understanding Statistics, Understanding Measurement, and Understanding Qualitative Research. The books provide researchers with guides to understanding, writing, and evaluating social research. Each volume demonstrates how research should be represented, including how to write up the methodology as well as the research findings. Each volume also reviews how to appropriately evaluate published research. Focus Group Discussions addresses the challenges associated with conducting and writing focus group research. It provides detailed guidance on the practical and theoretical considerations in conducting focus group discussions including: designing the discussion guide, recruiting participants, training a field team, moderating techniques and ethical considerations. Monique Hennink describes how a methodology section is read and evaluated by others, such as journal reviewers or ...

  17. Preparation of core-crosslinked linear-dendritic copolymer micelles with enhanced stability and their application for drug solubilisation.

    Science.gov (United States)

    Zhou, Zhengyuan; Forbes, Robert T; D'Emanuele, Antony

    2017-05-15

    In this study we explore the preparation of core-crosslinked micelles of linear-dendritic methoxy-poly(ethylene glycol) (MPEG)-co-poly(ester-sulfide) (PES) polymers to improve the stability of such polymeric micelle systems against premature disintegration and drug release. A series of MPEG-PES copolymers were synthesised via stepwise reactions of acetylation and thiol-ene photoreaction. Surface tension measurement showed that the copolymers with ethenyl surface groups could self-associate in dilute aqueous solutions to form micelles. Crosslinking within the micelle cores in the presence of dithioerythritol (DTT) linker was initiated under UV radiation. The formation of core-crosslinked micelles was confirmed by HPLC in combination with charged aerosol detection (CAD). The copolymers were found to readily hydrolyse under acidic conditions due to the ester-containing dendrons. Drug solubilisation capacities of the micellar solutions were determined using griseofulvin as a poorly water-soluble model drug. The solubility of griseofulvin showed a 10-fold enhancement in 1% w/v micelle solution and increased with the concentration of the copolymers. Drug release studies indicated that a more sustained release of griseofulvin was achieved for the core-crosslinked micelles compared to the non-crosslinked micelles, attributable to greater stability of the crosslinked core structure. The findings of this study present a new pathway towards developing biodegradable polymeric nanocarriers. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Early detection of metabolic and energy disorders by thermal time series stochastic complexity analysis

    Energy Technology Data Exchange (ETDEWEB)

    Lutaif, N.A. [Departamento de Clínica Médica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP (Brazil); Palazzo, R. Jr [Departamento de Telemática, Faculdade de Engenharia Elétrica e Computação, Universidade Estadual de Campinas, Campinas, SP (Brazil); Gontijo, J.A.R. [Departamento de Clínica Médica, Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Campinas, SP (Brazil)

    2014-01-17

    Maintenance of thermal homeostasis in rats fed a high-fat diet (HFD) is associated with changes in their thermal balance. The thermodynamic relationship between heat dissipation and energy storage is altered by the ingestion of high-energy diet content. Observation of thermal registers of core temperature behavior, in humans and rodents, permits identification of some characteristics of time series, such as autoreference and stationarity that fit adequately to a stochastic analysis. To identify this change, we used, for the first time, a stochastic autoregressive model, the concepts of which match those associated with physiological systems involved and applied in male HFD rats compared with their appropriate standard food intake age-matched male controls (n=7 per group). By analyzing a recorded temperature time series, we were able to identify when thermal homeostasis would be affected by a new diet. The autoregressive time series model (AR model) was used to predict the occurrence of thermal homeostasis, and this model proved to be very effective in distinguishing such a physiological disorder. Thus, we infer from the results of our study that maximum entropy distribution as a means for stochastic characterization of temperature time series registers may be established as an important and early tool to aid in the diagnosis and prevention of metabolic diseases due to their ability to detect small variations in thermal profile.

  19. Early detection of metabolic and energy disorders by thermal time series stochastic complexity analysis

    Directory of Open Access Journals (Sweden)

    N.A. Lutaif

    2014-01-01

    Full Text Available Maintenance of thermal homeostasis in rats fed a high-fat diet (HFD is associated with changes in their thermal balance. The thermodynamic relationship between heat dissipation and energy storage is altered by the ingestion of high-energy diet content. Observation of thermal registers of core temperature behavior, in humans and rodents, permits identification of some characteristics of time series, such as autoreference and stationarity that fit adequately to a stochastic analysis. To identify this change, we used, for the first time, a stochastic autoregressive model, the concepts of which match those associated with physiological systems involved and applied in male HFD rats compared with their appropriate standard food intake age-matched male controls (n=7 per group. By analyzing a recorded temperature time series, we were able to identify when thermal homeostasis would be affected by a new diet. The autoregressive time series model (AR model was used to predict the occurrence of thermal homeostasis, and this model proved to be very effective in distinguishing such a physiological disorder. Thus, we infer from the results of our study that maximum entropy distribution as a means for stochastic characterization of temperature time series registers may be established as an important and early tool to aid in the diagnosis and prevention of metabolic diseases due to their ability to detect small variations in thermal profile.

  20. Early detection of metabolic and energy disorders by thermal time series stochastic complexity analysis.

    Science.gov (United States)

    Lutaif, N A; Palazzo, R; Gontijo, J A R

    2014-01-01

    Maintenance of thermal homeostasis in rats fed a high-fat diet (HFD) is associated with changes in their thermal balance. The thermodynamic relationship between heat dissipation and energy storage is altered by the ingestion of high-energy diet content. Observation of thermal registers of core temperature behavior, in humans and rodents, permits identification of some characteristics of time series, such as autoreference and stationarity that fit adequately to a stochastic analysis. To identify this change, we used, for the first time, a stochastic autoregressive model, the concepts of which match those associated with physiological systems involved and applied in male HFD rats compared with their appropriate standard food intake age-matched male controls (n=7 per group). By analyzing a recorded temperature time series, we were able to identify when thermal homeostasis would be affected by a new diet. The autoregressive time series model (AR model) was used to predict the occurrence of thermal homeostasis, and this model proved to be very effective in distinguishing such a physiological disorder. Thus, we infer from the results of our study that maximum entropy distribution as a means for stochastic characterization of temperature time series registers may be established as an important and early tool to aid in the diagnosis and prevention of metabolic diseases due to their ability to detect small variations in thermal profile.

  1. REPARATION AND FLUORESCENT PROPERTIES OF Eu3+-CONTAINING CORE-SHELL NANOPARTICLES

    Institute of Scientific and Technical Information of China (English)

    Zheng-hui Wang; Li-feng yan; Qing-shi Zhu

    2003-01-01

    By using a two-stage soapless emulsion polymerization, four kinds of core-shell nanoparticles have been prepared,which are composed of a polystyrene core having an average diameter of 256 nm and a poly(methyl methacrylate-co-acrylic acid) shell. The transmission electron microscopy (TEM) micrographs and the atomic force microscopy (AFM) images evidenced the presence of a core-shell structure. In the infrared spectra, the shift of VCOOH to lower wavenumber with increasing Eu3+ ion content indicates that coordination between the oxygen of the carboxylic group and Eu3+ has occurred.The fluorescence intensity of 5D0-7F2 transition was observed to reach its maximum with a carboxyl group molar percentage of 40% in the shell and an Eu3+/-COO- molar ratio of 1:3. The fluorescence intensity ratio of 5D0-7F2 to 5D0-7F1 transition reached its maximum with an Eu3+/-COO- molar ratio of 1:3 for all the four series.

  2. Conceptual study of advanced PWR core design. Development of advanced PWR core neutronics analysis system

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Chang Hyo; Kim, Seung Cho; Kim, Taek Kyum; Cho, Jin Young; Lee, Hyun Cheol; Lee, Jung Hun; Jung, Gu Young [Seoul National University, Seoul (Korea, Republic of)

    1995-08-01

    The neutronics design system of the advanced PWR consists of (i) hexagonal cell and fuel assembly code for generation of homogenized few-group cross sections and (ii) global core neutronics analysis code for computations of steady-state pin-wise or assembly-wise core power distribution, core reactivity with fuel burnup, control rod worth and reactivity coefficients, transient core power, etc.. The major research target of the first year is to establish the numerical method and solution of multi-group diffusion equations for neutronics code development. Specifically, the following studies are planned; (i) Formulation of various numerical methods such as finite element method(FEM), analytical nodal method(ANM), analytic function expansion nodal(AFEN) method, polynomial expansion nodal(PEN) method that can be applicable for the hexagonal core geometry. (ii) Comparative evaluation of the numerical effectiveness of these methods based on numerical solutions to various hexagonal core neutronics benchmark problems. Results are follows: (i) Formulation of numerical solutions to multi-group diffusion equations based on numerical methods. (ii) Numerical computations by above methods for the hexagonal neutronics benchmark problems such as -VVER-1000 Problem Without Reflector -VVER-440 Problem I With Reflector -Modified IAEA PWR Problem Without Reflector -Modified IAEA PWR Problem With Reflector -ANL Large Heavy Water Reactor Problem -Small HTGR Problem -VVER-440 Problem II With Reactor (iii) Comparative evaluation on the numerical effectiveness of various numerical methods. (iv) Development of HEXFEM code, a multi-dimensional hexagonal core neutronics analysis code based on FEM. In the target year of this research, the spatial neutronics analysis code for hexagonal core geometry(called NEMSNAP-H temporarily) will be completed. Combination of NEMSNAP-H with hexagonal cell and assembly code will then equip us with hexagonal core neutronics design system. (Abstract Truncated)

  3. “1+1+3”三段化教学模式下的城乡规划专业核心课程群优化研究∗%Study on Optimization of Urban and Rural Planning Specialty Core Curriculum Group in “1+1+3”Three Segment Type Teaching Mode

    Institute of Scientific and Technical Information of China (English)

    吕静

    2015-01-01

    Jilin Jianzhu University takes the new requirement to adapt to the discipline and professional development as the starting point. According to process of specialty cognition of students and professional teaching rules, the school actively promote the reform in teaching basic platform , the teaching contents and the curriculum system. The college focus on the connection of course group construction in the longitudinal and transverse in optimization study of core curriculum group , to ensure to cultivate students' ability to smoothly connected among different stages and to achieve the teaching reform which takes "thick foundation, high quality, strong ability"as the core, and takes the practicing ability promotion as the goal.%吉林建筑大学以适应城乡规划学学科建设及专业发展的新要求为出发点,根据学生对专业的认知进程和专业教学的规律,积极推进在课程体系、教学基础平台和教学内容的改革,从而建构起“1+1+3”的三段化教学模式。在核心课程群优化研究上注重课程群建设在纵向和横向的衔接,以确保学生能力的培养在各阶段之间得以顺畅衔接,架构学生“厚基础、高素质、强能力”为核心能力培养的教学改革目标。

  4. Statistical analysis of the core authors groups of domestic nursing discipline during the Eleventh Five-Year%“十一五”期间国内护理学科核心著者群体的统计分析

    Institute of Scientific and Technical Information of China (English)

    李锐臻; 韩世范; 程金莲; 王益锵

    2013-01-01

    目的 调查“十一五”期间国内护理学科学术研究队伍的现状.方法 利用综合指数法确定出学科核心著者群体,从文献计量学角度,对其年龄结构、机构分布、地域分布、高被引文献主题及其研究内容进行统计分析.结果 “十一五”期间护理学科核心著者群体以40 ~ 59岁年龄段的研究人员最多;理论型著者18名,应用型著者27名;75.56%的核心著者分布在北京市、上海市、广东省;73.24%的高被引文献主题分布在护理管理、临床护理、护理教育领域.结论 应注重改善护理学科学术研究队伍的年龄结构,优化学科研究资源的配置,提高应用型研究的比例.%Objective To investigate the status of academic research team of domestic nursing discipline during the Eleventh Five-Year.Methods Subject core author groups were identified by using comprehensive index method.The age structure,institution distribution,regional distribution,high cited literature themes and research content were analyzed from the perspective of literature metrology.Results The prevalent age of core author groups was ranged from 40 to 59.There were 18 theoretical authors,and 27 applied authors.About 75.56% core authors distributed in Beijing,Shanghai,Guangdong province,and 73.24% cited literature subject distributed in the field of nursing management,clinical nursing and nursing education.Conclusion The age structure of academic research team should be improved,and resource allocation of subject research should be optimized,so as to improve the proportion of applied research.

  5. On the Evolution of the Dense Core Mass Function

    CERN Document Server

    Williams, Jonathan J Swift Jonathan P

    2008-01-01

    The mass distributions of dense cores in star-forming regions are measured to have a shape similar to the initial mass function of stars. This has been generally interpreted to mean that the constituent cores will form individual stars or stellar systems at a nearly constant star formation efficiency. This article presents a series of numerical experiments evolving distributions of dense cores into stars to quantify the effects of stellar multiplicity, global core fragmentation, and a varying star formation efficiency. We find that the different evolutionary schemes have an overall small effect on the shape of the resultant distribution of stars. Our results imply that at the current level of observational accuracy the comparison between the mass functions of dense cores and stars alone is insufficient to discern between different evolutionary models. Observations over a wide range of mass scales including the high or low-mass tails of these distributions have the largest potential for discerning between diff...

  6. GREEN CORE HOUSE

    Directory of Open Access Journals (Sweden)

    NECULAI Oana

    2017-05-01

    Full Text Available The Green Core House is a construction concept with low environmental impact, having as main central element a greenhouse. The greenhouse has the innovative role to use the biomass energy provided by plants to save energy. Although it is the central piece, the greenhouse is not the most innovative part of the Green Core House, but the whole building ensemble because it integrates many other sustainable systems as "waste purification systems", "transparent photovoltaic panels" or "double skin façades".

  7. Birefringent hollow core fibers

    DEFF Research Database (Denmark)

    Roberts, John

    2007-01-01

    Hollow core photonic crystal fiber (HC-PCF), fabricated according to a nominally non-birefringent design, shows a degree of un-controlled birefringence or polarization mode dispersion far in excess of conventional non polarization maintaining fibers. This can degrade the output pulse in many...... and an increased overlap between the polarization modes at the glass interfaces. The interplay between these effects leads to a wavelength for optimum polarization maintenance, lambda(PM), which is detuned from the wavelength of highest birefringence. By a suitable fiber design involving antiresonance of the core...

  8. Birefringent hollow core fibers

    DEFF Research Database (Denmark)

    Roberts, John

    2007-01-01

    Hollow core photonic crystal fiber (HC-PCF), fabricated according to a nominally non-birefringent design, shows a degree of un-controlled birefringence or polarization mode dispersion far in excess of conventional non polarization maintaining fibers. This can degrade the output pulse in many...... and an increased overlap between the polarization modes at the glass interfaces. The interplay between these effects leads to a wavelength for optimum polarization maintenance, lambda(PM), which is detuned from the wavelength of highest birefringence. By a suitable fiber design involving antiresonance of the core...

  9. Stochastic Lie group integrators

    CERN Document Server

    Malham, Simon J A

    2007-01-01

    We present Lie group integrators for nonlinear stochastic differential equations with non-commutative vector fields whose solution evolves on a smooth finite dimensional manifold. Given a Lie group action that generates transport along the manifold, we pull back the stochastic flow on the manifold to the Lie group via the action, and subsequently pull back the flow to the corresponding Lie algebra via the exponential map. We construct an approximation to the stochastic flow in the Lie algebra via closed operations and then push back to the Lie group and then to the manifold, thus ensuring our approximation lies in the manifold. We call such schemes stochastic Munthe-Kaas methods after their deterministic counterparts. We also present stochastic Lie group integration schemes based on Castell--Gaines methods. These involve using an underlying ordinary differential integrator to approximate the flow generated by a truncated stochastic exponential Lie series. They become stochastic Lie group integrator schemes if...

  10. Rheumatoid Arthritis Educational Video Series

    Medline Plus

    Full Text Available ... Patient Webcasts / Rheumatoid Arthritis Educational Video Series Rheumatoid Arthritis Educational Video Series This series of five videos ... member of our patient care team. Managing Your Arthritis Managing Your Arthritis Managing Chronic Pain and Depression ...

  11. Rheumatoid Arthritis Educational Video Series

    Science.gov (United States)

    ... Patient Webcasts / Rheumatoid Arthritis Educational Video Series Rheumatoid Arthritis Educational Video Series This series of five videos ... member of our patient care team. Managing Your Arthritis Managing Your Arthritis Managing Chronic Pain and Depression ...

  12. Rheumatoid Arthritis Educational Video Series

    Medline Plus

    Full Text Available ... Corner / Patient Webcasts / Rheumatoid Arthritis Educational Video Series Rheumatoid Arthritis Educational Video Series This series of five videos was designed to help you learn more about Rheumatoid Arthritis (RA). You will learn how the diagnosis of ...

  13. Rheumatoid Arthritis Educational Video Series

    Science.gov (United States)

    ... Corner / Patient Webcasts / Rheumatoid Arthritis Educational Video Series Rheumatoid Arthritis Educational Video Series This series of five videos ... Your Arthritis Managing Chronic Pain and Depression in Arthritis Nutrition & Rheumatoid Arthritis Arthritis and Health-related Quality of Life ...

  14. Vibroacoustic Characterization of Corrugated-Core and Honeycomb-Core Sandwich Panels

    Science.gov (United States)

    Allen, Albert; Schiller, Noah

    2016-01-01

    The vibroacoustic characteristics of two candidate launch vehicle fairing structures, corrugated- core and honeycomb-core sandwich designs, were studied. The study of these structures has been motivated by recent risk reduction efforts focused on mitigating high noise levels within the payload bays of large launch vehicles during launch. The corrugated-core sandwich concept is of particular interest as a dual purpose structure due to its ability to harbor resonant noise control systems without appreciably adding mass or taking up additional volume. Specifically, modal information, wavelength dispersion, and damping were determined from a series of vibrometer measurements and subsequent analysis procedures carried out on two test panels. Numerical and analytical modeling techniques were also used to assess assumed material properties and to further illuminate underlying structural dynamic aspects. Results from the tests and analyses described herein may serve as a reference for additional vibroacoustic studies involving these or similar structures.

  15. The efficacy of a supervised and a home-based core strengthening programme in adults with poor core stability: a three-arm randomised controlled trial.

    Science.gov (United States)

    Chuter, V H; de Jonge, X A K Janse; Thompson, B M; Callister, R

    2015-03-01

    Poor core stability is linked to a range of musculoskeletal pathologies and core-strengthening programmes are widely used as treatment. Treatment outcomes, however, are highly variable, which may be related to the method of delivery of core strengthening programmes. We investigated the effect of identical 8 week core strengthening programmes delivered as either supervised or home-based on measures of core stability. Participants with poor core stability were randomised into three groups: supervised (n=26), home-based (n=26) or control (n=26). Primary outcomes were the Sahrmann test and the Star Excursion Balance Test (SEBT) for dynamic core stability and three endurance tests (side-bridge, flexor and Sorensen) for static core stability. The exercise programme was devised and supervised by an exercise physiologist. Analysis of covariance on the change from baseline over the 8 weeks showed that the supervised group performed significantly better on all core stability measures than both the home-based and control group. The home-based group produced significant improvements compared to the control group in all static core stability tests, but not in most of the dynamic core stability tests (Sahrmann test and two out of three directions of the SEBT). Our results support the use of a supervised core-strengthening programme over a home-based programme to maximise improvements in core stability, especially in its dynamic aspects. Based on our findings in healthy individuals with low core stability, further research is recommended on potential therapeutic benefits of supervised core-strengthening programmes for pathologies associated with low core stability. ACTRN12613000233729. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  16. Time series analysis

    CERN Document Server

    Madsen, Henrik

    2007-01-01

    ""In this book the author gives a detailed account of estimation, identification methodologies for univariate and multivariate stationary time-series models. The interesting aspect of this introductory book is that it contains several real data sets and the author made an effort to explain and motivate the methodology with real data. … this introductory book will be interesting and useful not only to undergraduate students in the UK universities but also to statisticians who are keen to learn time-series techniques and keen to apply them. I have no hesitation in recommending the book.""-Journa

  17. Applied time series analysis

    CERN Document Server

    Woodward, Wayne A; Elliott, Alan C

    2011-01-01

    ""There is scarcely a standard technique that the reader will find left out … this book is highly recommended for those requiring a ready introduction to applicable methods in time series and serves as a useful resource for pedagogical purposes.""-International Statistical Review (2014), 82""Current time series theory for practice is well summarized in this book.""-Emmanuel Parzen, Texas A&M University""What an extraordinary range of topics covered, all very insightfully. I like [the authors'] innovations very much, such as the AR factor table.""-David Findley, U.S. Census Bureau (retired)""…

  18. Eisenstein series and automorphic representations

    CERN Document Server

    Fleig, Philipp; Kleinschmidt, Axel; Persson, Daniel

    2015-01-01

    We provide an introduction to the theory of Eisenstein series and automorphic forms on real simple Lie groups G, emphasising the role of representation theory. It is useful to take a slightly wider view and define all objects over the (rational) adeles A, thereby also paving the way for connections to number theory, representation theory and the Langlands program. Most of the results we present are already scattered throughout the mathematics literature but our exposition collects them together and is driven by examples. Many interesting aspects of these functions are hidden in their Fourier coefficients with respect to unipotent subgroups and a large part of our focus is to explain and derive general theorems on these Fourier expansions. Specifically, we give complete proofs of Langlands' constant term formula for Eisenstein series on adelic groups G(A) as well as the Casselman--Shalika formula for the p-adic spherical Whittaker vector associated to unramified automorphic representations of G(Q_p). Somewhat ...

  19. Comparison of New and Old Sunspot Number Time Series

    Science.gov (United States)

    Cliver, E. W.

    2016-11-01

    Four new sunspot number time series have been published in this Topical Issue: a backbone-based group number in Svalgaard and Schatten ( Solar Phys., 2016; referred to here as SS, 1610 - present), a group number series in Usoskin et al. ( Solar Phys., 2016; UEA, 1749 - present) that employs active day fractions from which it derives an observational threshold in group spot area as a measure of observer merit, a provisional group number series in Cliver and Ling ( Solar Phys., 2016; CL, 1841 - 1976) that removed flaws in the Hoyt and Schatten ( Solar Phys. 179, 189, 1998a; 181, 491, 1998b) normalization scheme for the original relative group sunspot number (RG, 1610 - 1995), and a corrected Wolf (international, RI) number in Clette and Lefèvre ( Solar Phys., 2016; SN, 1700 - present). Despite quite different construction methods, the four new series agree well after about 1900. Before 1900, however, the UEA time series is lower than SS, CL, and SN, particularly so before about 1885. Overall, the UEA series most closely resembles the original RG series. Comparison of the UEA and SS series with a new solar wind B time series (Owens et al. in J. Geophys. Res., 2016; 1845 - present) indicates that the UEA time series is too low before 1900. We point out incongruities in the Usoskin et al. ( Solar Phys., 2016) observer normalization scheme and present evidence that this method under-estimates group counts before 1900. In general, a correction factor time series, obtained by dividing an annual group count series by the corresponding yearly averages of raw group counts for all observers, can be used to assess the reliability of new sunspot number reconstructions.

  20. In vitro evaluation of the fracture strength of all-ceramic core materials on zirconium posts.

    Science.gov (United States)

    Ozcan, Nihal; Sahin, Erdal

    2013-10-01

    For most endodontically treated teeth, tooth-colored post-core systems are preferable for esthetic reasons. Therefore, improvements in material strength must also consider tooth colored post-core complexes. The objective of this study was to evaluate the difference in tooth colored post-core complex strengths. A total of 33 human maxillary central incisor teeth were used for this study, with three groups of 11 teeth. Three different methods were used to fabricate all-ceramic post-core restorations: zirconia blanks, Cerec 3D-milled to one-piece post-core restorations (Test Group 1); feldspathic cores (from feldspathic prefabricated CAD/CAM blocks) adhesively luted to CosmoPost zirconia posts (Test Group 2); and IPS Empress cores directly pressed to CosmoPost zirconia posts (Test Group 3). All-ceramic crowns from feldspathic ceramic were constructed using a CAD/CAM system (Cerec 3D) for all specimens. The post-core complexes were tested to failure with the load applied at 45° angled relative to the tooth long axis. The load at fracture was recorded. The maximum fracture strength of the milled zirconia cores (Test Group 1) was 577 N; corresponding values for the milled feldspathic cores (Test Group 2) and the pressed cores (Test Group 3) were 586 and 585 N, respectively. Differences were not statistically significant at P cores adhesively luted on zirconia posts and one-piece all-ceramic zirconium post-core structures offer a viable alternative to conventional pressing.

  1. Theory of groups of finite order

    CERN Document Server

    Burnside, W

    2013-01-01

    After introducing permutation notation and defining group, the author discusses the simpler properties of group that are independent of their modes of representation; composition-series of groups; isomorphism of a group with itself; Abelian groups; groups whose orders are the powers of primes; Sylow's theorem; more. 18 illustrations. A classic introduction.

  2. Investigation of EAS cores

    Science.gov (United States)

    Shaulov, S. B.; Beyl, P. F.; Beysembaev, R. U.; Beysembaeva, E. A.; Bezshapov, S. P.; Borisov, A. S.; Cherdyntceva, K. V.; Chernyavsky, M. M.; Chubenko, A. P.; Dalkarov, O. D.; Denisova, V. G.; Erlykin, A. D.; Kabanova, N. V.; Kanevskaya, E. A.; Kotelnikov, K. A.; Morozov, A. E.; Mukhamedshin, R. A.; Nam, R. A.; Nesterova, N. M.; Nikolskaya, N. M.; Pavluchenko, V. P.; Piskal, V. V.; Puchkov, V. S.; Pyatovsky, S. E.; Ryabov, V. A.; Sadykov, T. Kh.; Schepetov, A. L.; Smirnova, M. D.; Stepanov, A. V.; Uryson, A. V.; Vavilov, Yu. N.; Vildanov, N. G.; Vildanova, L. I.; Zayarnaya, I. S.; Zhanceitova, J. K.; Zhukov, V. V.

    2017-06-01

    The development of nuclear-electromagnetic cascade models in air in the late forties have shown informational content of the study of cores of extensive air showers (EAS). These investigations were the main goal in different experiments which were carried out over many years by a variety of methods. Outcomes of such investigations obtained in the HADRON experiment using an X-ray emulsion chamber (XREC) as a core detector are considered. The Ne spectrum of EAS associated with γ-ray families, spectra of γ-rays (hadrons) in EAS cores and the Ne dependence of the muon number, ⟨Nμ⟩, in EAS with γ-ray families are obtained for the first time at energies of 1015-1017 eV with this method. A number of new effects were observed, namely, an abnormal scaling violation in hadron spectra which are fundamentally different from model predictions, an excess of muon number in EAS associated with γ-ray families, and the penetrating component in EAS cores. It is supposed that the abnormal behavior of γ-ray spectra and Ne dependence of the muon number are explained by the emergence of a penetrating component in the 1st PCR spectrum `knee' range. Nuclear and astrophysical explanations of the origin of the penetrating component are discussed. The necessity of considering the contribution of a single close cosmic-ray source to explain the PCR spectrum in the knee range is noted.

  3. Some Core Contested Concepts

    Science.gov (United States)

    Chomsky, Noam

    2015-01-01

    Core concepts of language are highly contested. In some cases this is legitimate: real empirical and conceptual issues arise. In other cases, it seems that controversies are based on misunderstanding. A number of crucial cases are reviewed, and an approach to language is outlined that appears to have strong conceptual and empirical motivation, and…

  4. Looking for Core Values

    Science.gov (United States)

    Carter, Margie

    2010-01-01

    People who view themselves as leaders, not just managers or teachers, are innovators who focus on clarifying core values and aligning all aspects of the organization with these values to grow their vision. A vision for an organization can't be just one person's idea. Visions grow by involving people in activities that help them name and create…

  5. Nucleosome Core Particle

    Science.gov (United States)

    1997-01-01

    Nucleosome Core Particle grown on STS-81. The fundamental structural unit of chromatin and is the basis for organization within the genome by compaction of DNA within the nucleus of the cell and by making selected regions of chromosomes available for transcription and replication. Principal Investigator's are Dr. Dan Carter and Dr. Gerard Bunick of New Century Pharmaceuticals.

  6. Investigation of EAS cores

    Directory of Open Access Journals (Sweden)

    Shaulov S.B.

    2017-01-01

    Full Text Available The development of nuclear-electromagnetic cascade models in air in the late forties have shown informational content of the study of cores of extensive air showers (EAS. These investigations were the main goal in different experiments which were carried out over many years by a variety of methods. Outcomes of such investigations obtained in the HADRON experiment using an X-ray emulsion chamber (XREC as a core detector are considered. The Ne spectrum of EAS associated with γ-ray families, spectra of γ-rays (hadrons in EAS cores and the Ne dependence of the muon number, ⟨Nμ⟩, in EAS with γ-ray families are obtained for the first time at energies of 1015–1017 eV with this method. A number of new effects were observed, namely, an abnormal scaling violation in hadron spectra which are fundamentally different from model predictions, an excess of muon number in EAS associated with γ-ray families, and the penetrating component in EAS cores. It is supposed that the abnormal behavior of γ-ray spectra and Ne dependence of the muon number are explained by the emergence of a penetrating component in the 1st PCR spectrum ‘knee’ range. Nuclear and astrophysical explanations of the origin of the penetrating component are discussed. The necessity of considering the contribution of a single close cosmic-ray source to explain the PCR spectrum in the knee range is noted.

  7. The Earth's Core.

    Science.gov (United States)

    Jeanloz, Raymond

    1983-01-01

    The nature of the earth's core is described. Indirect evidence (such as that determined from seismological data) indicates that it is an iron alloy, solid toward its center but otherwise liquid. Evidence also suggests that it is the turbulent flow of the liquid that generates the earth's magnetic field. (JN)

  8. Some Core Contested Concepts

    Science.gov (United States)

    Chomsky, Noam

    2015-01-01

    Core concepts of language are highly contested. In some cases this is legitimate: real empirical and conceptual issues arise. In other cases, it seems that controversies are based on misunderstanding. A number of crucial cases are reviewed, and an approach to language is outlined that appears to have strong conceptual and empirical motivation, and…

  9. Languages for Dublin Core.

    Science.gov (United States)

    Baker, Thomas

    1998-01-01

    Focusing on languages for the Dublin Core, examines the experience of some related ways to seek semantic interoperability through simplicity: planned languages, interlingua constructs, and pidgins. Also defines the conceptual and organizational problem of maintaining a metadata standard in multiple languages. (AEF)

  10. Core calculations of JMTR

    Energy Technology Data Exchange (ETDEWEB)

    Nagao, Yoshiharu [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment

    1998-03-01

    In material testing reactors like the JMTR (Japan Material Testing Reactor) of 50 MW in Japan Atomic Energy Research Institute, the neutron flux and neutron energy spectra of irradiated samples show complex distributions. It is necessary to assess the neutron flux and neutron energy spectra of an irradiation field by carrying out the nuclear calculation of the core for every operation cycle. In order to advance core calculation, in the JMTR, the application of MCNP to the assessment of core reactivity and neutron flux and spectra has been investigated. In this study, in order to reduce the time for calculation and variance, the comparison of the results of the calculations by the use of K code and fixed source and the use of Weight Window were investigated. As to the calculation method, the modeling of the total JMTR core, the conditions for calculation and the adopted variance reduction technique are explained. The results of calculation are shown. Significant difference was not observed in the results of neutron flux calculations according to the difference of the modeling of fuel region in the calculations by K code and fixed source. The method of assessing the results of neutron flux calculation is described. (K.I.)

  11. The core and cosmopolitans

    DEFF Research Database (Denmark)

    Dahlander, Linus; Frederiksen, Lars

    2012-01-01

    Users often interact and help each other solve problems in communities, but few scholars have explored how these relationships provide opportunities to innovate. We analyze the extent to which people positioned within the core of a community as well as people that are cosmopolitans positioned...

  12. Adult educators' core competences

    DEFF Research Database (Denmark)

    Wahlgren, Bjarne

    2016-01-01

    environment as well as the kind of adult education concerned (e.g. basic education, work-related education etc.). However, it seems that it is possible to identify certain competence requirements which transcend national, cultural and functional boundaries. This research note summarises these common or “core...

  13. Adult educators' core competences

    DEFF Research Database (Denmark)

    Wahlgren, Bjarne

    2016-01-01

    environment as well as the kind of adult education concerned (e.g. basic education, work-related education etc.). However, it seems that it is possible to identify certain competence requirements which transcend national, cultural and functional boundaries. This research note summarises these common or “core...

  14. A generalization of the theory of Coleman power series

    OpenAIRE

    Ota, Kazuto

    2014-01-01

    Shinichi Kobayashi found a generalization of the Coleman power series theory to formal groups of elliptic curves and applied it to a study of $p$-adic height pairings. In this paper, we generalize his theory of Coleman power series to general formal groups.

  15. Little Herder Reading Series.

    Science.gov (United States)

    Bureau of Indian Affairs (Dept. of Interior), Washington, DC.

    The Little Herder Reading Series is comprised of 4 volumes based on the life of a Navajo Indian girl. The books are written in English blank verse and describe many facets of Indian life. The volumes contain illustrations by Hoke Denetsosie which give a pictorial representation of the printed verse. The reading level is for the middle and upper…

  16. Composition: Unity - Diversity series

    DEFF Research Database (Denmark)

    Bergstrøm-Nielsen, Carl

    2015-01-01

    Unity-Diversity series are open compositions to be realised by improvising musicians. See more about my composition practise in the entry "Composition - General Introduction". This work is licensed under a Creative Commons "by-nc" License. You may for non-commercial purposes use and distribute it...

  17. Parent's Journal. [Videotape Series].

    Science.gov (United States)

    1999

    Parent's Journal is a set of 16 videotapes for parents of prenatal, infant, and toddler-age children, created by the Alaska Native Home Base Video Project of the Tlingit and Haida Head Start Program. This series offers culturally relevant solutions to the challenges of parenting, drawing on the life stories and experiences of capable mothers and…

  18. Family Feathers. [Videotape Series].

    Science.gov (United States)

    1999

    Family Feathers is a set of 18 videotapes for parents of preschool children, created by the Alaska Native Home Base Video Project of the Tlingit and Haida Head Start Program. This series offers culturally relevant solutions to the challenges of parenting, drawing on practical advice from Tlingit and Haida parents, wisdom from elders, and some of…

  19. Visual time series analysis

    DEFF Research Database (Denmark)

    Fischer, Paul; Hilbert, Astrid

    2012-01-01

    commands, our application is select-and-click-driven. It allows to derive many different sequences of deviations for a given time series and to visualize them in different ways in order to judge their expressive power and to reuse the procedure found. For many transformations or model-ts, the user may...

  20. Composition: Unity - Diversity series

    DEFF Research Database (Denmark)

    Bergstrøm-Nielsen, Carl

    2015-01-01

    Unity-Diversity series are open compositions to be realised by improvising musicians. See more about my composition practise in the entry "Composition - General Introduction". This work is licensed under a Creative Commons "by-nc" License. You may for non-commercial purposes use and distribute it...

  1. Discrimination. Opposing Viewpoints Series.

    Science.gov (United States)

    Williams, Mary E., Ed.

    Books in the Opposing Viewpoints series challenge readers to question their own opinions and assumptions. By reading carefully balanced views, readers confront new ideas on the topic of interest. The Civil Rights Act of 1964, which prohibited job discrimination based on age, race, religion, gender, or national origin, provided the groundwork for…

  2. SOME PROPERTIES OF MULTIPLE TAYLOR SERIES AND RANDOM TAYLOR SERIES

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Some polar coordinates are used to determine the domain and the ball of convergence of a multiple Taylor series. In this domain and in this ball the series converges,converges absolutely and converges uniformly on any compact set. Growth and other properties of the series may also be studied. For some random multiple Taylor series there are some corresponding properties.

  3. Fibonacci Series on Microstructures

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ It is a big challenge for materials scientists to produce highly ordered micro- and nanostructures in a designed pattern with uniform size and shape.By controlling the geometry and the stress upon cooling, CAS researchers coaxed a microstructure to selfassemble into the triangular tessellation and Fibonacci number patterns on its surface. Their work ‘Triangular and Fibonacci number patterns driven by stress on core/shell microstructures' was published on the August 5 issue of Science.

  4. Group X

    Energy Technology Data Exchange (ETDEWEB)

    Fields, Susannah

    2007-08-16

    This project is currently under contract for research through the Department of Homeland Security until 2011. The group I was responsible for studying has to remain confidential so as not to affect the current project. All dates, reference links and authors, and other distinguishing characteristics of the original group have been removed from this report. All references to the name of this group or the individual splinter groups has been changed to 'Group X'. I have been collecting texts from a variety of sources intended for the use of recruiting and radicalizing members for Group X splinter groups for the purpose of researching the motivation and intent of leaders of those groups and their influence over the likelihood of group radicalization. This work included visiting many Group X websites to find information on splinter group leaders and finding their statements to new and old members. This proved difficult because the splinter groups of Group X are united in beliefs, but differ in public opinion. They are eager to tear each other down, prove their superiority, and yet remain anonymous. After a few weeks of intense searching, a list of eight recruiting texts and eight radicalizing texts from a variety of Group X leaders were compiled.

  5. Introduction to time series and forecasting

    CERN Document Server

    Brockwell, Peter J

    2016-01-01

    This book is aimed at the reader who wishes to gain a working knowledge of time series and forecasting methods as applied to economics, engineering and the natural and social sciences. It assumes knowledge only of basic calculus, matrix algebra and elementary statistics. This third edition contains detailed instructions for the use of the professional version of the Windows-based computer package ITSM2000, now available as a free download from the Springer Extras website. The logic and tools of time series model-building are developed in detail. Numerous exercises are included and the software can be used to analyze and forecast data sets of the user's own choosing. The book can also be used in conjunction with other time series packages such as those included in R. The programs in ITSM2000 however are menu-driven and can be used with minimal investment of time in the computational details. The core of the book covers stationary processes, ARMA and ARIMA processes, multivariate time series and state-space mod...

  6. Development of core design and analyses technology for integral reactor

    Energy Technology Data Exchange (ETDEWEB)

    Zee, Sung Quun; Lee, C. C.; Song, J. S. and others

    1999-03-01

    Integral reactors are developed for the applications such as sea water desalination, heat energy for various industries, and power sources for large container ships. In order to enhance the inherent and passive safety features, low power density concept is chosen for the integral reactor SMART. Moreover, ultra-longer cycle and boron-free operation concepts are reviewed for better plant economy and simple design of reactor system. Especially, boron-free operation concept brings about large difference in core configurations and reactivity controls from those of the existing large size commercial nuclear power plants and also causes many differences in the safety aspects. The ultimate objectives of this study include detailed core design of a integral reactor, development of the core design system and technology, and finally acquisition of the system design certificate. The goal of the first stage is the conceptual core design, that is, to establish the design bases and requirements suitable for the boron-free concept, to develop a core loading pattern, to analyze the nuclear, thermal and hydraulic characteristics of the core and to perform the core shielding design. Interface data for safety and performance analyses including fuel design data are produced for the relevant design analysis groups. Nuclear, thermal and hydraulic, shielding design and analysis code systems necessary for the core conceptual design are established through modification of the existing design tools and newly developed methodology and code modules. Core safety and performance can be improved by the technology development such as boron-free core optimization, advaned core monitoring and operational aid system. Feasiblity study on the improvement of the core protection and monitoring system will also contribute toward core safety and performance. Both the conceptual core design study and the related technology will provide concrete basis for the next design phase. This study will also

  7. Spatially resolved measurement of rock core porosity.

    Science.gov (United States)

    Marica, F; Chen, Q; Hamilton, A; Hall, C; Al, T; Balcom, B J

    2006-01-01

    Density weighted, centric scan, Conical SPRITE MRI techniques are applied in the current work for local porosity measurements in fluid saturated porous media. The methodology is tested on a series of sandstone core samples. These samples vary in both porosity and degree of local heterogeneity due to bedding plane structure. The MRI porosity measurement is in good agreement with traditional gravimetric measurements of porosity. Spatially resolved porosity measurements reveal significant porosity variation in some samples. This novel MRI technique should have applications to the characterization of local porosity in a wide variety of porous media.

  8. Detection of the translational oscillations of the Earth's solid inner core based on the international superconducting gravimeter observations

    Institute of Scientific and Technical Information of China (English)

    SUN Heping; XU Jianqiao; B.Ducarme

    2004-01-01

    Based on the 21 series of the high precision tidal gravity observations recorded using superconducting gravimeters (SG) at 14 stations distributed globally (in totally about 86 years), the translational oscillations of the Earth's solid inner core (ESIC) is detected in this paper. All observations are divided into two groups with G-Ⅰ group (8 relatively longer observational series) and G-Ⅱ group (13 relatively shorter observational series). The detailed corrections to minute original observations for each station are carried out, the error data due to the earthquakes, power supply impulses and some perturbations as change in atmospheric pressure and so on are carefully deleted for the first step, the gravity residuals are obtained after removing further synthetic tidal gravity signals. The Fast Fourier Transform analysis is carried out for each residual series, the estimations of the product spectral densities in the sub-tidal band are obtained by using a multi-station staking technique. The 8 common peaks are found after further removing the remaining frequency dependent pressure signals. The eigenperiods, quality factors and resonant strengths for these peaks are simulated. The numerical results show that the discrepancies of the eigenperiods for 3 of 8 peaks, compared to those of theoretical computation given by Smith, are only 0.4%, -0.4% and 1.0%. This coincidence signifies that the dynamical phenomenon of the Earth's solid inner core can be detected by using high precision ground gravity observations. The reliability of the numerical computation is also checked, the spectral peak splitting phenomenon induced by Earth's rotation and ellipticity is preliminary discussed in this paper.

  9. CAC - NUCLEAR THERMAL ROCKET CORE ANALYSIS CODE

    Science.gov (United States)

    Clark, J. S.

    1994-01-01

    One of the most important factors in the development of nuclear rocket engine designs is to be able to accurately predict temperatures and pressures throughout a fission nuclear reactor core with axial hydrogen flow through circular coolant passages. CAC is an analytical prediction program to study the heat transfer and fluid flow characteristics of a circular coolant passage. CAC predicts as a function of time axial and radial fluid conditions, passage wall temperatures, flow rates in each coolant passage, and approximate maximum material temperatures. CAC incorporates the hydrogen properties model STATE to provide fluid-state relations, thermodynamic properties, and transport properties of molecular hydrogen in any fixed ortho-para combination. The program requires the general core geometry, the core material properties as a function of temperature, the core power profile, and the core inlet conditions as function of time. Although CAC was originally developed in FORTRAN IV for use on an IBM 7094, this version is written in ANSI standard FORTRAN 77 and is designed to be machine independent. It has been successfully compiled on IBM PC series and compatible computers running MS-DOS with Lahey F77L, a Sun4 series computer running SunOS 4.1.1, and a VAX series computer running VMS 5.4-3. CAC requires 300K of RAM under MS-DOS, 422K of RAM under SunOS, and 220K of RAM under VMS. No sample executable is provided on the distribution medium. Sample input and output data are included. The standard distribution medium for this program is a 5.25 inch 360K MS-DOS format diskette. CAC was developed in 1966, and this machine independent version was released in 1992. IBM-PC and IBM are registered trademarks of International Business Machines. Lahey F77L is a registered trademark of Lahey Computer Systems, Inc. SunOS is a trademark of Sun Microsystems, Inc. VMS is a trademark of Digital Equipment Corporation. MS-DOS is a registered trademark of Microsoft Corporation.

  10. Analytical chemistry methods for metallic core components: Revision March 1985

    Energy Technology Data Exchange (ETDEWEB)

    1985-03-01

    This standard provides analytical chemistry methods for the analysis of alloys used to fabricate core components. These alloys are 302, 308, 316, 316-Ti, and 321 stainless steels and 600 and 718 Inconels and they may include other 300-series stainless steels.

  11. Cutting Tools. Youth Training Scheme. Core Exemplar Work Based Project.

    Science.gov (United States)

    Further Education Staff Coll., Blagdon (England).

    This trainer's guide is intended to assist supervisors of work-based career training projects in teaching students to compare the performance of two different types of engineering cutting tools and to determine their cost-effectiveness and efficiency. The guide is one in a series of core curriculum modules that is intended for use in combination…

  12. Application of Core Dynamics Modeling to Core-Mantle Interactions

    Science.gov (United States)

    Kuang, Weijia

    2003-01-01

    Observations have demonstrated that length of day (LOD) variation on decadal time scales results from exchange of axial angular momentum between the solid mantle and the core. There are in general four core-mantle interaction mechanisms that couple the core and the mantle. Of which, three have been suggested likely the dominant coupling mechanism for the decadal core-mantle angular momentum exchange, namely, gravitational core-mantle coupling arising from density anomalies in the mantle and in the core (including the inner core), the electromagnetic coupling arising from Lorentz force in the electrically conducting lower mantle (e.g. D-layer), and the topographic coupling arising from non-hydrostatic pressure acting on the core-mantle boundary (CMB) topography. In the past decades, most effort has been on estimating the coupling torques from surface geomagnetic observations (kinematic approach), which has provided insights on the core dynamical processes. In the meantime, it also creates questions and concerns on approximations in the studies that may invalidate the corresponding conclusions. The most serious problem is perhaps the approximations that are inconsistent with dynamical processes in the core, such as inconsistencies between the core surface flow beneath the CMB and the CMB topography, and that between the D-layer electric conductivity and the approximations on toroidal field at the CMB. These inconsistencies can only be addressed with numerical core dynamics modeling. In the past few years, we applied our MoSST (Modular, Scalable, Self-consistent and Three-dimensional) core dynamics model to study core-mantle interactions together with geodynamo simulation, aiming at assessing the effect of the dynamical inconsistencies in the kinematic studies on core-mantle coupling torques. We focus on topographic and electromagnetic core-mantle couplings and find that, for the topographic coupling, the consistency between the core flow and the CMB topography is

  13. Exploiting Symmetry in Integer Convex Optimization using Core Points

    CERN Document Server

    Herr, Katrin; Schürmann, Achill

    2012-01-01

    We consider convex programming problems with integrality constraints that are invariant under a linear symmetry group. We define a core point of such a symmetry group as an integral point for which the convex hull of its orbit does not contain integral points other than the orbit points themselves. These core points allow us to decompose symmetric integer convex programming problems. Especially for symmetric integer linear programs we describe two algorithms based on this decomposition. Using a characterization of core points for direct products of symmetric groups, we show that prototype implementations can compete with state-of-the art commercial solvers and solve an open MIPLIB problem.

  14. Sandwiched structural panel having a bi-directional core structure

    Science.gov (United States)

    Weddendorf, Bruce (Inventor)

    1995-01-01

    A structural panel assembly has a bi-directional core structure sandwiched between and secured to a pair of outer side wall members. The core structure is formed from first and second perpendicular series of elongated strip members having crenelated configurations. The strip members in the first series thereof are transversely interwoven with the strip members in the second series thereof in a manner such that crest portions of the strip members in the first series overlie and oppose trough portions of the strip members in the second series, and trough portions of the strip members in the first series underlie and oppose crest portions of the strip members in the second series. The crest portions of all of the strip members lie generally in a first plane and are secured to the inner side of one of the panel assembly outer side walls, and the trough portions of all of the strip members lie generally in a second plane and are secured to the inner side of the other panel assembly outer side wall.

  15. Group morphology

    NARCIS (Netherlands)

    Roerdink, Jos B.T.M.

    2000-01-01

    In its original form, mathematical morphology is a theory of binary image transformations which are invariant under the group of Euclidean translations. This paper surveys and extends constructions of morphological operators which are invariant under a more general group TT, such as the motion group

  16. USGS Core Research Center (CRC) Collection of Core

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The Core Research Center (CRC) was established in 1974 by the U.S. Geological Survey (USGS) to preserve valuable rock cores for use by scientists and educators from...

  17. Ice Cores of the National Ice Core Laboratory

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The U.S. National Ice Core Laboratory (NICL) is a facility for storing, curating, and studying ice cores recovered from the polar regions of the world. It provides...

  18. Core level photoemission of rotaxanes : A summary on binding energies

    NARCIS (Netherlands)

    Mendoza, S. M.; Berna, J.; Perez, E. M.; Kay, E. R.; Mateo-Alonso, A.; De Nadai, C.; Zhang, S.; Baggerman, J.; Wiering, P. G.; Leigh, D. A.; Prato, M.; Brouwer, A.M.; Rudolf, P.; Nadaï, C. De

    2008-01-01

    Several rotaxanes were studied by XPS in the form of thin films or monolayers on gold substrates. Here we report a database of photoemission spectra of the C 1s, N 1s and F 1s core levels. Binding energy ranges are summarized, classifying the core levels according to the chemical groups that form pa

  19. Core level photoemission of rotaxanes: A summary on binding energies

    Energy Technology Data Exchange (ETDEWEB)

    Mendoza, S.M. [Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen (Netherlands); Berna, J.; Perez, E.M.; Kay, E.R. [School of Chemistry, University of Edinburgh, King' s Buildings, West Mains Road, Edinburgh EH9 3JJ (United Kingdom); Mateo-Alonso, A. [Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, 34127 Trieste (Italy); De Nadai, C. [Laboratoire Interdisciplinaire de Spectroscopie Electronique, Facultes Universitaires Notre Dame de la Paix, 61 Rue de Bruxelles, B-5000 Namur (Belgium); Zhang, S. [School of Chemistry, University of Edinburgh, King' s Buildings, West Mains Road, Edinburgh EH9 3JJ (United Kingdom); Baggerman, J.; Wiering, P.G. [Van' t Hoff Institute for Molecular Sciences, University of Amsterdam, Nieuwe Achtergracht 129, NL-1018 WS Amsterdam (Netherlands); Leigh, D.A. [School of Chemistry, University of Edinburgh, King' s Buildings, West Mains Road, Edinburgh EH9 3JJ (United Kingdom); Prato, M. [Dipartimento di Scienze Farmaceutiche, Universita di Trieste, Piazzale Europa 1, 34127 Trieste (Italy); Brouwer, A.M. [Van' t Hoff Institute for Molecular Sciences, University of Amsterdam, Nieuwe Achtergracht 129, NL-1018 WS Amsterdam (Netherlands); Rudolf, P. [Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, 9747 AG Groningen (Netherlands)], E-mail: P.Rudolf@rug.nl

    2008-09-15

    Several rotaxanes were studied by XPS in the form of thin films or monolayers on gold substrates. Here we report a database of photoemission spectra of the C 1s, N 1s and F 1s core levels. Binding energy ranges are summarized, classifying the core levels according to the chemical groups that form part of the rotaxanes.

  20. Core Outlet Temperature Study

    Energy Technology Data Exchange (ETDEWEB)

    Moisseytsev, A. [Argonne National Laboratory (ANL), Argonne, IL (United States); Hoffman, E. [Argonne National Laboratory (ANL), Argonne, IL (United States); Majumdar, S. [Argonne National Laboratory (ANL), Argonne, IL (United States)

    2008-07-28

    It is a known fact that the power conversion plant efficiency increases with elevation of the heat addition temperature. The higher efficiency means better utilization of the available resources such that higher output in terms of electricity production can be achieved for the same size and power of the reactor core or, alternatively, a lower power core could be used to produce the same electrical output. Since any nuclear power plant, such as the Advanced Burner Reactor, is ultimately built to produce electricity, a higher electrical output is always desirable. However, the benefits of the higher efficiency and electricity production usually come at a price. Both the benefits and the disadvantages of higher reactor outlet temperatures are analyzed in this work.

  1. Dynamics of core accretion

    Science.gov (United States)

    Nelson, Andrew F.; Ruffert, Maximilian

    2013-02-01

    We perform three-dimensional hydrodynamic simulations of gas flowing around a planetary core of mass Mpl = 10M⊕ embedded in a near Keplerian background flow, using a modified shearing box approximation. We assume an ideal gas behaviour following an equation of state with a fixed ratio of the specific heats, γ = 1.42, consistent with the conditions of a moderate-temperature background disc with solar composition. No radiative heating or cooling is included in the models. We employ a nested grid hydrodynamic code implementing the `Piecewise Parabolic Method' with as many as six fixed nested grids, providing spatial resolution on the finest grid comparable to the present-day diameters of Neptune and Uranus. We find that a strongly dynamically active flow develops such that no static envelope can form. The activity is not sensitive to plausible variations in the rotation curve of the underlying disc. It is sensitive to the thermodynamic treatment of the gas, as modelled by prescribed equations of state (either `locally isothermal' or `locally isentropic') and the temperature of the background disc material. The activity is also sensitive to the shape and depth of the core's gravitational potential, through its mass and gravitational softening coefficient. Each of these factors influences the magnitude and character of hydrodynamic feedback of the small-scale flow on the background, and we conclude that accurate modelling of such feedback is critical to a complete understanding of the core accretion process. The varying flow pattern gives rise to large, irregular eruptions of matter from the region around the core which return matter to the background flow: mass in the envelope at one time may not be found in the envelope at any later time. No net mass accretion into the envelope is observed over the course of the simulation and none is expected, due to our neglect of cooling. Except in cases of very rapid cooling however, as defined by locally isothermal or

  2. Series elastic actuators

    Science.gov (United States)

    Williamson, Matthew M.

    1995-01-01

    This thesis presents the design, construction, control and evaluation of a novel for controlled actuator. Traditional force controlled actuators are designed from the premise that 'Stiffer is better'. This approach gives a high bandwidth system, prone to problems of contact instability, noise, and low power density. The actuator presented in this thesis is designed from the premise that 'Stiffness isn't everything'. The actuator, which incorporates a series elastic element, trades off achievable bandwidth for gains in stable, low noise force control, and protection against shock loads. This thesis reviews related work in robot force control, presents theoretical descriptions of the control and expected performance from a series elastic actuator, and describes the design of a test actuator constructed to gather performance data. Finally the performance of the system is evaluated by comparing the performance data to theoretical predictions.

  3. Some core contested concepts.

    Science.gov (United States)

    Chomsky, Noam

    2015-02-01

    Core concepts of language are highly contested. In some cases this is legitimate: real empirical and conceptual issues arise. In other cases, it seems that controversies are based on misunderstanding. A number of crucial cases are reviewed, and an approach to language is outlined that appears to have strong conceptual and empirical motivation, and to lead to conclusions about a number of significant issues that differ from some conventional beliefs.

  4. Causality between time series

    CERN Document Server

    Liang, X San

    2014-01-01

    Given two time series, can one tell, in a rigorous and quantitative way, the cause and effect between them? Based on a recently rigorized physical notion namely information flow, we arrive at a concise formula and give this challenging question, which is of wide concern in different disciplines, a positive answer. Here causality is measured by the time rate of change of information flowing from one series, say, X2, to another, X1. The measure is asymmetric between the two parties and, particularly, if the process underlying X1 does not depend on X2, then the resulting causality from X2 to X1 vanishes. The formula is tight in form, involving only the commonly used statistics, sample covariances. It has been validated with touchstone series purportedly generated with one-way causality. It has also been applied to the investigation of real world problems; an example presented here is the cause-effect relation between two climate modes, El Ni\\~no and Indian Ocean Dipole, which have been linked to the hazards in f...

  5. Central core disease

    Directory of Open Access Journals (Sweden)

    Jungbluth Heinz

    2007-05-01

    Full Text Available Abstract Central core disease (CCD is an inherited neuromuscular disorder characterised by central cores on muscle biopsy and clinical features of a congenital myopathy. Prevalence is unknown but the condition is probably more common than other congenital myopathies. CCD typically presents in infancy with hypotonia and motor developmental delay and is characterized by predominantly proximal weakness pronounced in the hip girdle; orthopaedic complications are common and malignant hyperthermia susceptibility (MHS is a frequent complication. CCD and MHS are allelic conditions both due to (predominantly dominant mutations in the skeletal muscle ryanodine receptor (RYR1 gene, encoding the principal skeletal muscle sarcoplasmic reticulum calcium release channel (RyR1. Altered excitability and/or changes in calcium homeostasis within muscle cells due to mutation-induced conformational changes of the RyR protein are considered the main pathogenetic mechanism(s. The diagnosis of CCD is based on the presence of suggestive clinical features and central cores on muscle biopsy; muscle MRI may show a characteristic pattern of selective muscle involvement and aid the diagnosis in cases with equivocal histopathological findings. Mutational analysis of the RYR1 gene may provide genetic confirmation of the diagnosis. Management is mainly supportive and has to anticipate susceptibility to potentially life-threatening reactions to general anaesthesia. Further evaluation of the underlying molecular mechanisms may provide the basis for future rational pharmacological treatment. In the majority of patients, weakness is static or only slowly progressive, with a favourable long-term outcome.

  6. Structure determination of KLaS2, KPrS2, KEuS2, KGdS2, KLuS2, KYS2, RbYS2, NaLaS2 and crystal-chemical analysis of the group 1 and thallium(I) rare-earth sulfide series.

    Science.gov (United States)

    Fábry, Jan; Havlák, Lubomír; Dušek, Michal; Vaněk, Přemysl; Drahokoupil, Jan; Jurek, Karel

    2014-04-01

    One of the purposes of this work is to provide a crystallographic review of group 1 and thallium rare-earth ternary sulfides M(+)Ln(3+)S2. We have therefore determined crystal structures of KLaS2, KPrS2, KEuS2, KGdS2, KLuS2, KYS2, RbYS2, which belong to the α-NaFeO2 structural family (R3m), as well as NaLaS2, which is derived from the disordered NaCl structural type (Fm3m). The determined structures were compared with known members of the group 1 as well as thallium(I) rare-earth sulfides by the standard tools of crystal-chemical analysis such as comparison of bond-valences, analysis of interatomic distances and comparison of the unit-cell parameters. The results indicate why the cubic structural type is limited to Li(+) and Na(+) members of the series only. The analysis has also revealed frequent problems in the reported crystal structures, especially in the determination of the K(+) compounds, probably due to severe absorption and different accuracy and sensitivity of various instruments. Intense diffuse scattering has been discovered in NaLaS2, which will be the subject of further investigation. The newly determined as well as already known structures are summarized, together with critical comments about possible errors in the previous structure determinations.

  7. The use of television series in health education.

    Science.gov (United States)

    Elkamel, F

    1995-06-01

    This paper reviews evidence of the impact which television generally, and drama series in particular, can have on health beliefs, attitudes and behaviours. It describes how a television series, The Family House, was planned in Egypt to disseminate key health messages in an entertaining context. As only a very small number of television series were specifically developed to address health issues, and even fewer were evaluated, this paper presents important new data derived from focus group discussions and survey interviews which help in understanding the potential television series can have for health education. Finally, the paper presents data on the cost-effectiveness of The Family House series.

  8. Numerical analysis and experiment to identify origin of buckling in rapid cycling synchrotron core

    Energy Technology Data Exchange (ETDEWEB)

    Morita, Y., E-mail: yuichi.morita@kek.jp [High Energy Accelerator Research Organization (KEK), 1-1 Oho, Tsukuba, Ibaraki (Japan); Kageyama, T. [High Energy Accelerator Research Organization (KEK), 1-1 Oho, Tsukuba, Ibaraki (Japan); Akoshima, M. [The National Institute of Advanced Industrial Science and Technology (AIST), 1-1-1 Umezono, Tsukuba, Ibaraki (Japan); Torizuka, S.; Tsukamoto, M. [National Institute for Materials Science (NIMS), 1-2-1 Sengen, Tsukuba, Ibaraki (Japan); Yamashita, S. [International Center for Elementary Particle Physics (ICEPP), University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo (Japan); Yoshikawa, N. [Institute of Industrial Science (IIS), University of Tokyo, 4-6-1 Komaba, Meguro, Tokyo (Japan)

    2013-11-11

    The accelerating cavities used in the rapid cycling synchrotron (RCS) of the Japan Proton Accelerator Research Complex (J-PARC) are loaded with magnetic alloy (MA) cores. Over lengthly periods of RCS operation, significant reductions in the impedance of the cavities resulting from the buckling of the cores were observed. A series of thermal structural simulations and compressive strength tests showed that the buckling can be attributed to the low-viscosity epoxy resin impregnation of the MA core that causes the stiffening of the originally flexible MA–ribbon–wound core. Our results showed that thermal stress can be effectively reduced upon using a core that is not epoxy-impregnated. -- Highlights: • Study to identify the origin of buckling in the MA cores is presented. • Thermal stress simulations and compressive strength tests were carried out. • Results show that thermal stress is the origin of core buckling. • Thermal stress can be reduced by using cores without epoxy impregnation.

  9. Prevalence of anisotropic shell growth in rare earth core-shell upconversion nanocrystals.

    Science.gov (United States)

    Zhang, Chao; Lee, Jim Yang

    2013-05-28

    Through a series of carefully executed experiments, we discovered the prevalence of anisotropic shell growth in many upconversion NaREF4 systems caused by a combination of factors: selective adsorption of ligands on the core surface due to the core crystal structure, ligand etching, and the lattice mismatch between core and shell components. This could lead to incomplete shell formation in core-shell nanocrystals under certain conditions. Shell growth is always faster in the a and b crystallographic directions than in the c direction. In the case of a larger lattice mismatch between the core and shell, shell growth only occurs in the a and b directions resulting in an oblong core-shell structure. These findings are useful for rationalizing shell-dependent emission properties, understanding the emission mechanisms in complex core-shell nanostructures, and for creating accurate models of core-shell designs for multifunctionality and optimal performance in applications.

  10. Core-seis: a code for LMFBR core seismic analysis

    Energy Technology Data Exchange (ETDEWEB)

    Chellapandi, P.; Ravi, R.; Chetal, S.C.; Bhoje, S.B. [Indira Gandhi Centre for Atomic Research, Kalpakkam (India). Reactor Group

    1995-12-31

    This paper deals with a computer code CORE-SEIS specially developed for seismic analysis of LMFBR core configurations. For demonstrating the prediction capability of the code, results are presented for one of the MONJU reactor core mock ups which deals with a cluster of 37 subassemblies kept in water. (author). 3 refs., 7 figs., 2 tabs.

  11. Core Exercises: Why You Should Strengthen Your Core Muscles

    Science.gov (United States)

    Healthy Lifestyle Fitness You know core exercises are good for you — but do you include core exercises in your fitness routine? Here's why ... 18, 2014 Original article: http://www.mayoclinic.org/healthy-lifestyle/fitness/in-depth/core-exercises/art-20044751 . Mayo Clinic Footer Legal Conditions and ...

  12. Parsimonious Linear Fingerprinting for Time Series

    Science.gov (United States)

    2010-09-01

    like to detect such groups of harmonics. Fig. 1(d) gives a quick preview of the visualization and effectiveness of the proposed PLiF method: For the...coefficients of each individual frequency. As we find harmonic frequency sets in music , in real time- series like motions, we will expect to usually find

  13. A Time Series Forecasting Method

    Directory of Open Access Journals (Sweden)

    Wang Zhao-Yu

    2017-01-01

    Full Text Available This paper proposes a novel time series forecasting method based on a weighted self-constructing clustering technique. The weighted self-constructing clustering processes all the data patterns incrementally. If a data pattern is not similar enough to an existing cluster, it forms a new cluster of its own. However, if a data pattern is similar enough to an existing cluster, it is removed from the cluster it currently belongs to and added to the most similar cluster. During the clustering process, weights are learned for each cluster. Given a series of time-stamped data up to time t, we divide it into a set of training patterns. By using the weighted self-constructing clustering, the training patterns are grouped into a set of clusters. To estimate the value at time t + 1, we find the k nearest neighbors of the input pattern and use these k neighbors to decide the estimation. Experimental results are shown to demonstrate the effectiveness of the proposed approach.

  14. Main features and mineralization of black shale series of Mesoproterozoic erathem Laoling group Zhenzhumen formation of Jilin Province%吉林省中元古界老岭群珍珠门组黑色岩系主要特征及其成矿作用

    Institute of Scientific and Technical Information of China (English)

    李宏帅

    2014-01-01

    The minerals in the black rock series have attracted the attention of people. Organic carbon mass fraction are 35%~1.17%, with an average of 10.14%, in carbonaceous slate of Mesoproterozoic erathem Laoling group Zhenzhumen low subformation of Jilin Province. The background value of gold, copper, cobalt is high, average value is 0.148×10-6,52.94× 10-6,8.46× 10-6 respectively, and is 123, 43, 78 times in the mountains of the eastern China average values respectively. The black rock series is the obvious ore source bed of these elements. A copper cobalt deposits of small size is found in the black rock series of Zhenzhumen low subformation of Tonghua Dadingzi. The copper cobalt deposits contain the gold lens, the gold of average grade is 52.8 × 10-6, and it is quite a potential auriferous copper cobalt deposit.%黑色岩系中的矿产,早已为人们所瞩目,我省中元古宙老岭群珍珠门下亚组碳质板岩中有机碳质量分数达35.00%~1.17%,平均10.14%。其中金、铜、钴背景高,平均值分别为:0.148×10-6,52.94×10-6,8.46×10-6,是中国东部山区平均值123、43、78、倍。是这些元素的明显矿源层。在通化大顶子珍珠门下亚组黑色岩系形成一处铜钴小型矿床,其中含有金矿扁豆体,平均品位52.8×10-6,是一处颇有远景的含金铜钴矿床。

  15. ICF Core Sets for stroke

    National Research Council Canada - National Science Library

    Szilvia Geyh; Alarcos Cieza; Jan Schouten; Hugh Dickson; Peter Frommelt; Zaliha Omar; Nenad Kostanjsek; Haim Ring; Gerold Stucki

    2004-01-01

    Objective: To report on the results of the consensus process integrating evidence from preliminary studies to develop the first version of the Comprehensive ICF Core Set and the Brief ICF Core Set for stroke. Methods...

  16. Group devaluation and group identification

    NARCIS (Netherlands)

    Leach, C.W.; Rodriguez Mosquera, P.M.; Vliek, M.L.W.; Hirt, E.

    2010-01-01

    In three studies, we showed that increased in-group identification after (perceived or actual) group devaluation is an assertion of a (preexisting) positive social identity that counters the negative social identity implied in societal devaluation. Two studies with real-world groups used order manip

  17. Combustion and Energy Transfer Experiments: A Laboratory Model for Linking Core Concepts across the Science Curriculum

    Science.gov (United States)

    Barreto, Jose C.; Dubetz, Terry A.; Schmidt, Diane L.; Isern, Sharon; Beatty, Thomas; Brown, David W.; Gillman, Edward; Alberte, Randall S.; Egiebor, Nosa O.

    2007-01-01

    Core concepts can be integrated throughout lower-division science and engineering courses by using a series of related, cross-referenced laboratory experiments. Starting with butane combustion in chemistry, the authors expanded the underlying core concepts of energy transfer into laboratories designed for biology, physics, and engineering. This…

  18. ROSA full-core and DNBR capabilities

    Energy Technology Data Exchange (ETDEWEB)

    Gibcus, H.P.M.; Verhagen, F.C.M.; Wakker, P.H. [NRG, Arnhem (Netherlands)

    2012-11-01

    This paper presents the latest developments of the ROSA (Reloading Optimization by Simulated Annealing) code system with an emphasis on the first full-core version and the minimum DNBR (Departure from Nucleate Boiling Ratio) as a new optimization parameter. Designing the core loading pattern of nuclear power plants is becoming a more and more complex task. This task becomes even more complicated if asymmetries in the core loading pattern arise, for instance due to damaged fuel assemblies. For over almost two decades ROSA, NRG's (Nuclear Research and consultancy Group) loading pattern optimization code system for PWRs, has proven to be a valuable tool to reactor operators in accomplishing this task. To improve the use of ROSA for designing asymmetric loading patterns, NRG has developed a full-core version of ROSA besides the original quarter-core version which requires rotational symmetry in the computational domain. The extension of ROSA with DNBR as an optimization parameter is part of ROSA's continuous development. (orig.)

  19. ROSA full-core and DNBR capabilities

    Energy Technology Data Exchange (ETDEWEB)

    Gibcus, H.P.M.; Verhagen, F.C.M.; Wakker, P.H. [NRG, Arnhem (Netherlands)

    2013-06-15

    The latest developments of the ROSA (Reloading Optimization by Simulated Annealing) code system with an emphasis on the first full-core version and the minimum DNBR (Departure from Nucleate Boiling Ratio) as a new optimization parameter are presented. Designing the core loading pattern of nuclear power plants is becoming a more and more complex task. This task becomes even more complicated if asymmetries in the core loading pattern arise, for instance due to damaged fuel assemblies. For over almost 2 decades ROSA, NRG's (Nuclear Research and consultancy Group) loading pattern optimization code system for PWRs, has proven to be a valuable tool to reactor operators in accomplishing this task. To improve the use of ROSA for designing asymmetric loading patterns, NRG has developed a full-core version of ROSA besides the original quarter-core version which requires rotational symmetry in the computational domain. The extension of ROSA with DNBR as an optimization parameter is part of ROSA's continuous development. (orig.)

  20. Hollow-Core Fiber Lamp

    Science.gov (United States)

    Yi, Lin (Inventor); Tjoelker, Robert L. (Inventor); Burt, Eric A. (Inventor); Huang, Shouhua (Inventor)

    2016-01-01

    Hollow-core capillary discharge lamps on the millimeter or sub-millimeter scale are provided. The hollow-core capillary discharge lamps achieve an increased light intensity ratio between 194 millimeters (useful) and 254 millimeters (useless) light than conventional lamps. The capillary discharge lamps may include a cone to increase light output. Hollow-core photonic crystal fiber (HCPCF) may also be used.

  1. On core stability and extendability

    OpenAIRE

    Shellshear, Evan

    2007-01-01

    This paper investigates conditions under which the core of a TU cooperative game is stable. In particular the author extends the idea of extendability to find new conditions under which the core is stable. It is also shown that these new conditions are not necessary for core stability.

  2. Dual-core Itanium Processor

    CERN Multimedia

    2006-01-01

    Intel’s first dual-core Itanium processor, code-named "Montecito" is a major release of Intel's Itanium 2 Processor Family, which implements the Intel Itanium architecture on a dual-core processor with two cores per die (integrated circuit). Itanium 2 is much more powerful than its predecessor. It has lower power consumption and thermal dissipation.

  3. On core stability and extendability

    OpenAIRE

    Shellshear, Evan

    2007-01-01

    This paper investigates conditions under which the core of a TU cooperative game is stable. In particular the author extends the idea of extendability to find new conditions under which the core is stable. It is also shown that these new conditions are not necessary for core stability.

  4. Superconducting shielded core reactor with reduced AC losses

    Energy Technology Data Exchange (ETDEWEB)

    Cha, Yung S.; Hull, John R.

    2006-04-04

    A superconducting shielded core reactor (SSCR) operates as a passive device for limiting excessive AC current in a circuit operating at a high power level under a fault condition such as shorting. The SSCR includes a ferromagnetic core which may be either closed or open (with an air gap) and extends into and through a superconducting tube or superconducting rings arranged in a stacked array. First and second series connected copper coils each disposed about a portion of the iron core are connected to the circuit to be protected and are respectively wound inside and outside of the superconducting tube or rings. A large impedance is inserted into the circuit by the core when the shielding capability of the superconducting arrangement is exceeded by the applied magnetic field generated by the two coils under a fault condition to limit the AC current in the circuit. The proposed SSCR also affords reduced AC loss compared to conventional SSCRs under continuous normal operation.

  5. Synchronization of ice core records via atmospheric gases

    Directory of Open Access Journals (Sweden)

    T. Blunier

    2007-06-01

    Full Text Available To interpret new high resolution climate records it becomes more and more important to know about the succession of climate events. Such knowledge is hard to get especially when dealing with different types of climate archives. Even for ice cores a direct synchronization between ice cores from Greenland and Antarctica has not been possible so far due to the lack of time markers occurring in both hemispheres. Fortunately, variations in the time series of global gas records can be used as indirect time markers. Here we discuss in detail the steps that are necessary to synchronize ice cores via global gas records exemplified on the synchronization of the EPICA ice core from Dronning Maud Land to a Greenland record from North GRIP.

  6. Introduction to Time Series Modeling

    CERN Document Server

    Kitagawa, Genshiro

    2010-01-01

    In time series modeling, the behavior of a certain phenomenon is expressed in relation to the past values of itself and other covariates. Since many important phenomena in statistical analysis are actually time series and the identification of conditional distribution of the phenomenon is an essential part of the statistical modeling, it is very important and useful to learn fundamental methods of time series modeling. Illustrating how to build models for time series using basic methods, "Introduction to Time Series Modeling" covers numerous time series models and the various tools f

  7. Square summable power series

    CERN Document Server

    de Branges, Louis

    2015-01-01

    This text for advanced undergraduate and graduate students introduces Hilbert space and analytic function theory, which is centered around the invariant subspace concept. The book's principal feature is the extensive use of formal power series methods to obtain and sometimes reformulate results of analytic function theory. The presentation is elementary in that it requires little previous knowledge of analysis, but it is designed to lead students to an advanced level of performance. This is achieved chiefly through the use of problems, many of which were proposed by former students. The book's

  8. Infinite sequences and series

    CERN Document Server

    Knopp, Konrad

    1956-01-01

    One of the finest expositors in the field of modern mathematics, Dr. Konrad Knopp here concentrates on a topic that is of particular interest to 20th-century mathematicians and students. He develops the theory of infinite sequences and series from its beginnings to a point where the reader will be in a position to investigate more advanced stages on his own. The foundations of the theory are therefore presented with special care, while the developmental aspects are limited by the scope and purpose of the book. All definitions are clearly stated; all theorems are proved with enough detail to ma

  9. Historia de las series

    OpenAIRE

    Cascajosa Virino, Concepción

    2017-01-01

    Reseña: Historia de las series de Toni de la Torre: la gran impostura Durante mucho tiempo los profesores de cine en España se han quejado (amargamente y en privado) de la recurrencia en la bibliografía de los trabajos de sus estudiantes de los libros de un autor conocido por la escasa calidad de sus textos, cuyos vistosos títulos garantizan que acaben en las estanterías de las bibliotecas universitarias. Es muy propio de la cultura española hacer duras aseveraciones en foros irrelevantes y, ...

  10. Development of silane grafted ZnO core shell nanoparticles loaded diglycidyl epoxy nanocomposites film for antimicrobial applications.

    Science.gov (United States)

    Suresh, S; Saravanan, P; Jayamoorthy, K; Ananda Kumar, S; Karthikeyan, S

    2016-07-01

    In this article a series of epoxy nanocomposites film were developed using amine functionalized (ZnO-APTES) core shell nanoparticles as the dispersed phase and a commercially available epoxy resin as the matrix phase. The functional group of the samples was characterized using FT-IR spectra. The most prominent peaks of epoxy resin were found in bare epoxy and in all the functionalized ZnO dispersed epoxy nanocomposites (ZnO-APTES-DGEBA). The XRD analysis of all the samples exhibits considerable shift in 2θ, intensity and d-spacing values but the best and optimum concentration is found to be 3% ZnO-APTES core shell nanoparticles loaded epoxy nanocomposites supported by FT-IR results. From TGA measurements, 100wt% residue is obtained in bare ZnO nanoparticles whereas in ZnO core shell nanoparticles grafted DGEBA residue percentages are 37, 41, 45, 46 and 52% for 0, 1, 3, 5 and 7% ZnO-APTES-DGEBA respectively, which is confirmed with ICP-OES analysis. From antimicrobial activity test, it was notable that antimicrobial activity of 7% ZnO-APTES core shell nanoparticles loaded epoxy nanocomposite film has best inhibition zone effect against all pathogens under study.

  11. From superatomic Au25(SR)18(-) to superatomic M@Au24(SR)18(q) core-shell clusters.

    Science.gov (United States)

    Jiang, De-en; Dai, Sheng

    2009-04-06

    Au(25)(SR)(18)(-) belongs to a new type of superatom that features an icosahedral Au(13) core-shell structure and a protective layer of six RS(Au-SR)(2) motifs. This superatom has a magic number of 8 free electrons that fully fill the 1s and 1p levels of the electron-shell model. By applying this superatom concept to the core-substitution chemistry of Au(25)(SR)(18)(-), we first scanned the periodic table for the potential core atom M by applying a simple rule derived from the 8-electron count and then optimized the selected candidates by density functional theory calculations to create many series of M@Au(24)(SR)(18)(q) core-shell nanoclusters. We found that 16 elements from groups 1, 2, and 10-14 of the periodic table can maintain both electronic and geometric structures of the original Au(25)(SR)(18)(-) magic cluster, indicating that the electron-counting rule based on the superatom concept is powerful in predicting viable M@Au(24)(SR)(18)(q) clusters. Our work opens up a promising area for experimental exploration.

  12. Effect of Rotation in Cloud Core Collapse

    Science.gov (United States)

    Tsuribe, T.

    stage by rapid growth of a nonspherical first core. Second, to mimic fragmentation processes of primordial clouds, the equation of state is approximated by a simple polytropic relation with γ ˜ 1.1. A series of numerical and semianalytical calculations of the rotating collapse of an initially spherical cloud shows a criterion for fragmentation of rotating polytropic cloud cores with γ=1.1. Fragmentation during core collapse is not expected to take place if the cloud thermal energy is greater than 0.3 times its gravitational energy at the initial stage of runaway collapse. The collapse of the central small core will not be halted by centrifugal force since a nonaxisymmetric waves will appear and the flow will converge to a self-similar flow until γ exceeds 4/3. Finally, we take into account the detailed non-equilibrium chemical reactions for primordial gas that consists of pure hydrogen. The parameters of the collapse and the condition of the fragmentation are compared with those of isothermal clouds. It is shown that the geometrical flatness of the central region of the disc is a good indicator for predicting whether the clouds fragment or not. If the flatness is greater than the critical value, ˜ 4π, a cloud fragments into filaments and blobs. On the other hand, if the flatness is smaller than the critical value, fragmentation is not expected before the central core formation even if the cooling is efficient and the total mass becomes much greater than the local Jeans mass at the center.

  13. Winning Cores in Parity Games

    DEFF Research Database (Denmark)

    Vester, Steen

    2016-01-01

    We introduce the novel notion of winning cores in parity games and develop a deterministic polynomial-time under-approximation algorithm for solving parity games based on winning core approximation. Underlying this algorithm are a number properties about winning cores which are interesting...... in their own right. In particular, we show that the winning core and the winning region for a player in a parity game are equivalently empty. Moreover, the winning core contains all fatal attractors but is not necessarily a dominion itself. Experimental results are very positive both with respect to quality...

  14. Series Bosch System Development

    Science.gov (United States)

    Abney, Morgan B.; Evans, Christopher; Mansell, Matt; Swickrath, Michael

    2012-01-01

    State-of-the-art (SOA) carbon dioxide (CO2) reduction technology for the International Space Station produces methane as a byproduct. This methane is subsequently vented overboard. The associated loss of hydrogen ultimately reduces the mass of oxygen that can be recovered from CO2 in a closed-loop life support system. As an alternative to SOA CO2 reduction technology, NASA is exploring a Series-Bosch system capable of reducing CO2 with hydrogen to form water and solid carbon. This results in 100% theoretical recovery of oxygen from metabolic CO2. In the past, Bosch-based technology did not trade favorably against SOA technology due to a high power demand, low reaction efficiencies, concerns with carbon containment, and large resupply requirements necessary to replace expended catalyst cartridges. An alternative approach to Bosch technology, labeled "Series-Bosch," employs a new system design with optimized multi-stage reactors and a membrane-based separation and recycle capability. Multi-physics modeling of the first stage reactor, along with chemical process modeling of the integrated system, has resulted in a design with potential to trade significantly better than previous Bosch technology. The modeling process and resulting system architecture selection are discussed.

  15. Series overview and introduction.

    Science.gov (United States)

    Alexander, Jeanne Leventhal; Dennerstein, Lorraine

    2007-11-01

    Studies and treatments for the symptomatic menopausal woman have been reviewed elsewhere. The aim of this clinical review series is to examine the evidence for the diagnosis and treatment of the woman who presents with distressing symptoms that she attributes to menopause, whose actual etiology may be a psychiatric disorder, a pre- or co-existing problem such as sleep or cognitive problems, or a dynamic interaction among one of these and a symptomatic menopause. This series of articles will review new research on somatic symptoms of depression, the depression continuum and its impact on morbidity and functioning, treatment issues related to remission of depression, cognitive decline or impairment secondary to a mood disorder, sleep problems in women and their impact on well-being and functioning, and attention and working memory problems in women. These will all be reviewed in the context of the vulnerable female patient and her experience of increased or new distressing symptoms during her menopausal transition. Recommendations for the diagnosis and management of women with psychiatric comorbidity and a symptomatic menopause are discussed.

  16. Uranium series, volcanic rocks

    Science.gov (United States)

    Vazquez, Jorge A.

    2014-01-01

    Application of U-series dating to volcanic rocks provides unique and valuable information about the absolute timing of crystallization and differentiation of magmas prior to eruption. The 238U–230Th and 230Th-226Ra methods are the most commonly employed for dating the crystallization of mafic to silicic magmas that erupt at volcanoes. Dates derived from the U–Th and Ra–Th methods reflect crystallization because diffusion of these elements at magmatic temperatures is sluggish (Cherniak 2010) and diffusive re-equilibration is insignificant over the timescales (less than or equal to 10^5 years) typically associated with pre-eruptive storage of nearly all magma compositions (Cooper and Reid 2008). Other dating methods based on elements that diffuse rapidly at magmatic temperatures, such as the 40Ar/39Ar and (U–Th)/He methods, yield dates for the cooling of magma at the time of eruption. Disequilibrium of some short-lived daughters of the uranium series such as 210Po may be fractionated by saturation of a volatile phase and can be employed to date magmatic gas loss that is synchronous with volcanic eruption (e.g., Rubin et al. 1994).

  17. Historical Heliophysical Series of the Ebro Observatory

    Science.gov (United States)

    Curto, J. J.; Solé, J. G.; Genescà, M.; Blanca, M. J.; Vaquero, J. M.

    2016-11-01

    We present the contents of the historical heliophysical series collected at the Ebro Observatory, as well as the actions carried out to restore and save these data and to conserve the physical media containing the data and the telescopes that helped to obtain them. We also discuss the results obtained with these measurements, describe how we disseminated them, and report on the investigations that we have carried out with this information. We show the evolution of the local solar indices such as the Ebro Sunspot Number (ESN), the Ebro Group Sunspot Number (EGSN), or the Ebro Sunspot Area (ESA), which are derived directly from our data. For verification purposes, these local solar indices have been compared to the international sunspot numbers published by SILSO. Our data are reliable and correlate well with the respective international series. Finally, as an example of the possibilities that the Ebro series offer, we explain the use of these data to elucidate one of the recent problems in solar physics: the discontinuity in international data known as the Waldmeier discontinuity and, in general, the ratio between sunspots and sunspot groups. In the Ebro Observatory series, no discontinuity such as this is detected. We instead observe a rather stable ratio in the spot or group rates. This result is in agreement with the hypothesis of Svalgaard (2010, ASP CS-428, 297) that the Waldmeier discontinuity is produced only on a procedural level, perhaps by a change in the criteria used in Zürich by Waldmeier or by changing external conditions.

  18. 一核多元、中和位育:中國大陸當代少數民族教育法律與政策述評One-core with Diversities, Justice and Harmony: An Analysis of Contemporary Education Laws and Policies of Minority Ethnic Groups in Mainland China

    Directory of Open Access Journals (Sweden)

    吳明海Ming-Hai Wu

    2014-09-01

    Full Text Available 從1950年代到現在,經過60多年的持續建設,中國大陸已經建成以憲法為核心的少數民族教育法律與政策的多元一體之制度體系,有力保障並促進少數民族與民族地區教育事業的健康發展。本研究採用文獻法,著重對有關民族教育的國家層級的法律與政策文本之基本原則和要點進行歸納。中國大陸民族教育法律政策體系建立在中華民族多元一體格局的文化傳統基礎之上,有深厚的歷史基礎與廣泛的群眾基礎,具有連續性、開放性與可持續發展性。其問題的關鍵是政策執行須與廉政吏治相結合,以中和位育為原則,切實落實到位,讓各族人民的子女與廣大教師真正得到實惠。With the continuous exploration and construction in the past over 60 years from 1949 to the present time, the government of Mainland China has established an educational law and policy system of minority ethnic groups with one-core: Chinese Constitution, in a diverse environment. This system has been effectively ensuring and promoting the health development of minority groups and the education in ethnic areas. Through the literature review, this study analyses the fundamental principles and the main points of national laws and policy documents relating to ethnic group education in Mainland China. The educational law and policy system of minority ethnic groups in Mainland China, which is set up upon the pluralistic-one structure of the national cultural traditions, has a profound historical foundation and broad mass base with continuity, openness and sustainability. The key issue is that the policy implementation must be combined with the construction of clean government, and must be based on the principle of justice and harmony, so that the policies will be put into practice and truly benefit the ethnic young generation and the teachers.

  19. Synthesis of Novel Carbosilane Dendrimers with Myo-inositol Cores

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    The preparation of carbosilane dendrimers with cores of myo-inositol and the outmost periphery groups of allyl groups has been reported.By using alternate hydrosilylation and alkenylation reactions, the dendrimer have been carried up to the third generation with 48 allyl groups on the periphery.

  20. Models of the earth's core

    Science.gov (United States)

    Stevenson, D. J.

    1981-01-01

    Combined inferences from seismology, high-pressure experiment and theory, geomagnetism, fluid dynamics, and current views of terrestrial planetary evolution lead to models of the earth's core with five basic properties. These are that core formation was contemporaneous with earth accretion; the core is not in chemical equilibrium with the mantle; the outer core is a fluid iron alloy containing significant quantities of lighter elements and is probably almost adiabatic and compositionally uniform; the more iron-rich inner solid core is a consequence of partial freezing of the outer core, and the energy release from this process sustains the earth's magnetic field; and the thermodynamic properties of the core are well constrained by the application of liquid-state theory to seismic and labroatory data.

  1. Local properties of Fourier series

    OpenAIRE

    Hüseyin Bor

    2000-01-01

    A theorem on local property of |N¯,pn|k summability of factored Fourier series, which generalizes some known results, and also a general theorem concerning the |N¯,pn|k summability factors of Fourier series have been proved.

  2. Series of Reciprocal Triangular Numbers

    Science.gov (United States)

    Bruckman, Paul; Dence, Joseph B.; Dence, Thomas P.; Young, Justin

    2013-01-01

    Reciprocal triangular numbers have appeared in series since the very first infinite series were summed. Here we attack a number of subseries of the reciprocal triangular numbers by methodically expressing them as integrals.

  3. GPS Position Time Series @ JPL

    Science.gov (United States)

    Owen, Susan; Moore, Angelyn; Kedar, Sharon; Liu, Zhen; Webb, Frank; Heflin, Mike; Desai, Shailen

    2013-01-01

    Different flavors of GPS time series analysis at JPL - Use same GPS Precise Point Positioning Analysis raw time series - Variations in time series analysis/post-processing driven by different users. center dot JPL Global Time Series/Velocities - researchers studying reference frame, combining with VLBI/SLR/DORIS center dot JPL/SOPAC Combined Time Series/Velocities - crustal deformation for tectonic, volcanic, ground water studies center dot ARIA Time Series/Coseismic Data Products - Hazard monitoring and response focused center dot ARIA data system designed to integrate GPS and InSAR - GPS tropospheric delay used for correcting InSAR - Caltech's GIANT time series analysis uses GPS to correct orbital errors in InSAR - Zhen Liu's talking tomorrow on InSAR Time Series analysis

  4. GPS Position Time Series @ JPL

    Science.gov (United States)

    Owen, Susan; Moore, Angelyn; Kedar, Sharon; Liu, Zhen; Webb, Frank; Heflin, Mike; Desai, Shailen

    2013-01-01

    Different flavors of GPS time series analysis at JPL - Use same GPS Precise Point Positioning Analysis raw time series - Variations in time series analysis/post-processing driven by different users. center dot JPL Global Time Series/Velocities - researchers studying reference frame, combining with VLBI/SLR/DORIS center dot JPL/SOPAC Combined Time Series/Velocities - crustal deformation for tectonic, volcanic, ground water studies center dot ARIA Time Series/Coseismic Data Products - Hazard monitoring and response focused center dot ARIA data system designed to integrate GPS and InSAR - GPS tropospheric delay used for correcting InSAR - Caltech's GIANT time series analysis uses GPS to correct orbital errors in InSAR - Zhen Liu's talking tomorrow on InSAR Time Series analysis

  5. The clinical significance of lobular neoplasia on breast core biopsy.

    Science.gov (United States)

    Karabakhtsian, Rouzan G; Johnson, Ronald; Sumkin, Jules; Dabbs, David J

    2007-05-01

    A core biopsy diagnosis of atypical ductal epithelial hyperplasia is upstaged on follow-up excisional biopsy (FUEB) to in situ or invasive carcinoma in about 20% of cases, thus prompting a FUEB. In contrast, upstaging information for a core biopsy diagnosis of pure lobular neoplasia (LN), without mass lesions or other risk-associated lesions is less clear. In this retrospective study, we report the largest consecutive series of patients who had a breast core biopsy diagnosis of LN and a FUEB. Core needle breast biopsies with a diagnosis of LN were retrieved from our files for the period 1999 to 2005, yielding 110 patients. One hundred and one patients had a follow-up surgical excision. Cases of LN with coexisting high-risk lesions (n=9, 10%) were excluded from the study. Patients with associated mass lesions all had benign findings (n=15, 16%) and had no impact on the study results. The remaining 77 core biopsies had no masses or risk lesions and were mammographically Breast Imaging Reporting and Data System 4 (BIRADS) for microcalcifications. Overall, 8/77 (10%) of patients with a radiographic BIRADS 4 image with calcifications and a core biopsy diagnosis of LN on core biopsy were upstaged on FUEB to ductal carcinoma in situ or invasive carcinoma. The numbers upstaged from core biopsies were as follows: atypical lobular hyperplasia (ALH) 4/52 (8%), mixed ALH/lobular carcinoma in situ (LCIS) 1/9 (10%), and pure LCIS 3/16 (19%). A core biopsy of LCIS with neoplastic epithelial calcifications was nearly 3 times more likely to be upstaged on FUEB compared with ALH. We conclude that a finding of LN on breast core biopsy in a patient with a BIRADS 4 image and calcifications is associated with a risk of 8% to 19% of upstaging to a treatable disease on FUEB.

  6. Subnanometer Control of Mean Core Size during Mesofluidic Synthesis of Small (D(core) Nanoparticles.

    Science.gov (United States)

    Elliott, Edward W; Haben, Patrick M; Hutchison, James E

    2015-11-03

    A convenient, single-step synthesis is reported that produces ligand-stabilized, water-soluble gold nanoparticles (AuNPs) with subnanometer-level precision of the mean core diameter over a range of 2-9 nm for a series of desired surface chemistries. The synthesis involves the reduction of a Au(III) species with sodium borohydride in the presence of a functionalized alkyl thiosulfate (Bunte salt) to yield thiolate-protected AuNPs. A key advantage of this synthesis is that simply adjusting the pH of the gold salt solution leads to control over the AuNP core size. The speciation of Au(III), and therefore the kinetics for its reduction and the core size produced, depends upon pH. The use of pH as the sole variable to control core size is a more reliable and convenient method than traditional approaches that rely on adjusting the concentrations and ratios of ligand, metal salt, and reducing agent. The average core size increased as the pH was raised for each ligand studied. Because the influence of pH was different for each of the ligands, working curves were plotted for each ligand to identify conditions to synthesize particles with specific, targeted core diameters. Using this approach, reaction conditions can be rapidly optimized using a combination of a mesofluidic reactor and small-angle X-ray scattering (SAXS) size analysis. The use of the mesofluidic reactor was needed to ensure fast mixing given the rapid kinetics for core formation. Using the reactor, it is possible to obtain reproducible sizes across multiple syntheses (size variation) and subnanometer control of the mean core dimensions. The synthetic method demonstrated here provides an attractive alternative to two-step syntheses involving ligand exchange because it is more efficient and eliminates the possibility of nanoparticle core size changes during exchange steps. This approach enables the development of "size ladders" of particles with the same surface chemistry for investigations of structure

  7. 旬阳-白河汉江以南地区下志留统梅子垭组地层铅锌金找矿预测%Lead-Zinc-Gold Prospecting Forecast in Lower Silurian Series Meiziya Group Stratum of Southern Hanjiang Area in Xunyang-Baihe

    Institute of Scientific and Technical Information of China (English)

    唐敏杰; 刘文革

    2013-01-01

    陕西旬阳-白河地区的下志留统梅子垭组地层是近年来发现的铅锌、金主要含矿层位,其岩性主要为次深海相沉积的富含Au、Ag、Hg、Sb、As、Zn、Ba等元素的碳硅质岩-碳酸盐岩-泥质岩组合的“黑色岩系”。铜铅锌矿体受该地层控制明显,金矿受地层中脆-韧性剪切带控制;矿产呈北西向带状展布,成矿元素分带较明显,自南向北成矿元素具有金-铜-铅锌水平分带的特点;在汉江以南的矿权空白区划分出印沟垭铅锌(铜)成矿远景区、西营-鹰子山铅锌、金成矿远景区、双河-茅坪地区金多金属成矿远景区及秦家老庄-平安金多金属成矿远景区,在热水沉积岩、构造及物化探异常发育地段找矿潜力较大。%In recent years , lower Silurian series Meiziya group has been found to be the main lead and zinc , gold-beared layer in Xunyang-Baihe area ,Shaanxi province .The main lithology is sub-marine sediments rich in elements of gold , sil-ver, mercury, antimny,arsenic, zinc, barium, etc, and combined with carbonaceous silicate-carbonatite-argillaceous rock ,and it always be named "black rock series".Copper , lead and zinc deposits are controlled obviously by these strata , but the gold mine are controlled by crisp ductile shear zone beared in these strata .The minerals are distributed in northwestern banding , the ore-forming elements have a distinctive zonation;from south to north , the elements have a feature of level zon-ing by gold-copper-lead and zinc .The author marked out three mineralized blocks in lower Silurian series Meiziya group at southern Hanjiang, that is Yingouya lead-zinc (copper) metallogenic prospect area , Xiying-Yingzishan lead-zinc-gold met-allogenic prospect area , and Shuanghe Maoping gold and multi-metal metallogenic prospect area , and Qinjialaozhuang Pin-gan gold and multi-metal metallogenic prospect area .It was recognized that there are much more prospecting

  8. Contractor renormalization group and the Haldane conjecture

    Energy Technology Data Exchange (ETDEWEB)

    Weinstein, Marvin

    2001-05-01

    The contractor renormalization group formalism (CORE) is a real-space renormalization group method which is the Hamiltonian analogue of the Wilson exact renormalization group equations. In an earlier paper [Phys. Rev. D 61, 034505 (2000)] I showed that the CORE method could be used to map a theory of free quarks and quarks interacting with gluons into a generalized frustrated Heisenberg antiferromagnet (HAF) and proposed using CORE methods to study these theories. Since generalizations of HAF's exhibit all sorts of subtle behavior which, from a continuum point of view, are related to topological properties of the theory, it is important to know that CORE can be used to extract this physics. In this paper I show that despite the folklore which asserts that all real-space renormalization group schemes are necessarily inaccurate, simple CORE computations can give highly accurate results even if one only keeps a small number of states per block and a few terms in the cluster expansion. In addition I argue that even very simple CORE computations give a much better qualitative understanding of the physics than naive renormalization group methods. In particular I show that the simplest CORE computation yields a first-principles understanding of how the famous Haldane conjecture works for the case of the spin-1/2 and spin-1 HAF.

  9. Group Grammar

    Science.gov (United States)

    Adams, Karen

    2015-01-01

    In this article Karen Adams demonstrates how to incorporate group grammar techniques into a classroom activity. In the activity, students practice using the target grammar to do something they naturally enjoy: learning about each other.

  10. MUYANG GROUP

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ With its headquarters in the historic city of Yangzhou,Jiangsu Muyang Group Co.,Ltd has since its founding in 1967 grown into a well-known group corporation whose activities cover research&development.project design,manufacturing,installation and services in a multitude of industries including feed machinery and engineering,storage engineering,grain machinery and engineering,environmental protection,conveying equipment and automatic control systems.

  11. Quantification of water-level variability effect on plant species populations using paleoecological and hydrological time series data

    Science.gov (United States)

    Roehl, Edwin A.; Conrads, Paul A.; Bernhardt, Christopher

    2012-01-01

    Soil cores provide valuable data on historical changes in vegetation and hydrologic conditions. Empirical models were developed to quantify the effect of meteorological and hydrologic forcing on plant species distributions over a 110-year period in Water Conservation Area 1 (WCA1) in the Florida Everglades, also known as the Arthur R. Marshall Loxahatchee National Wildlife Refuge. Empirical models that predict plant species distributions at sites within WCA1 were developed by linking temporally sparse seed bank data from soil cores with continuous multi-decadal daily meteorological and hydrologic time series data. The meteorological data included rainfall and maximum daily temperatures that spanned the entire study period of 110 years. The hydrologic data included stage data from two gages in WCA1 established in 1954. These stage data were hindcasted to be concurrent with the meteorological data by using correlation models that fit measured stages as a function of the meteorological parameters. The historical plant species data came from seven peat cores from WCA1. Different depths from each core were carbon-dated and assayed for relative percentages of 83 plant species using pollen counts. The oldest dates were more than 1,000 years old; however, only core data that overlapped the study period were used, for a total of 67 assays among the seven cores. Twenty-three of the species had ratios of at least 5 percent for one or more of the 67 assays, hereafter referred to as the "top23". Using the assays as input vectors, the top23 were grouped using the k-means clustering into four plant classes that represented the extent to which the various species have historically appeared together. This reduced the modeling problem to one of predicting the relative ratios of the four plant classes from the hindcasted stage time-series data. A separate empirical model was developed for each class using a multi-layer perceptron artificial neural network, which provides multivariate

  12. Abelian groups

    CERN Document Server

    Fuchs, László

    2015-01-01

    Written by one of the subject’s foremost experts, this book focuses on the central developments and modern methods of the advanced theory of abelian groups, while remaining accessible, as an introduction and reference, to the non-specialist. It provides a coherent source for results scattered throughout the research literature with lots of new proofs. The presentation highlights major trends that have radically changed the modern character of the subject, in particular, the use of homological methods in the structure theory of various classes of abelian groups, and the use of advanced set-theoretical methods in the study of undecidability problems. The treatment of the latter trend includes Shelah’s seminal work on the undecidability in ZFC of Whitehead’s Problem; while the treatment of the former trend includes an extensive (but non-exhaustive) study of p-groups, torsion-free groups, mixed groups, and important classes of groups arising from ring theory. To prepare the reader to tackle these topics, th...

  13. The diagram for phyllotactic series

    Directory of Open Access Journals (Sweden)

    Joanna Szymanowska-Pułka

    2014-01-01

    Full Text Available Many authors studying phyllotaxis in various plant species have reported the occurrence of many different numbers of contact parastichy pairs that are members of different Fibonacci-like series. On the basis of these reports a diagram was constructed in which any theoretically possible series was represented by the two first members of a given series.

  14. Core Competencies in Geriatric Dentistry Fellowship Programs: a Delphi Study.

    Science.gov (United States)

    Hogue, Christie M; Andrade, Allen D; Ruiz, Jorge G; Gibson, Gretchen

    2016-07-01

    The healthcare workforce is challenged with preparing for the increasing number of older persons and complexities of their healthcare needs. Fellowship trained geriatric dentists are charged with the task of addressing the dental needs of this vastly growing cohort.The purpose of this study is to formulate a set of competencies for Geriatric Dental Fellowship Training Programs. The Delphi technique-a series of three rounds of anonymous questionnaires to obtain the opinions of experts without bringing them together. In Round 1, we proposed 45 competencies based on findings in previous literature. In Round 2, there were 19 respondents whose edits narrowed our list to 39 competencies proposed by the participants. In Round 3, based on group consensus we formulated a final list of 42 competencies. Utilizing the Delphi process, a panel of geriatric dental experts identified a set of core competencies for curriculums in dental fellowship programs. Published 2016. This article is a U.S. Government work and is in the public domain in the USA.

  15. Introduction to time series analysis and forecasting

    CERN Document Server

    Montgomery, Douglas C; Kulahci, Murat

    2008-01-01

    An accessible introduction to the most current thinking in and practicality of forecasting techniques in the context of time-oriented data. Analyzing time-oriented data and forecasting are among the most important problems that analysts face across many fields, ranging from finance and economics to production operations and the natural sciences. As a result, there is a widespread need for large groups of people in a variety of fields to understand the basic concepts of time series analysis and forecasting. Introduction to Time Series Analysis and Forecasting presents the time series analysis branch of applied statistics as the underlying methodology for developing practical forecasts, and it also bridges the gap between theory and practice by equipping readers with the tools needed to analyze time-oriented data and construct useful, short- to medium-term, statistically based forecasts.

  16. Globe: Lecture series

    CERN Multimedia

    2007-01-01

    The LHC: an accelerator of science This series of lectures is all about understanding the scientific and technological challenges of the phenomenal LHC project and assessing its innovations through their everyday applications. Come and take a sneak preview of the LHC! Communicate: the Grid, a computer of global dimensions François Grey, head of communication in CERN’s Information Technology Department How will it be possible for the 15 million billion bytes of data generated by the LHC every year to be handled and stored by a computer that doesn’t have to be the size of a skyscraper? The computer scientists have the answer: the Grid, which will harness the power of tens of thousands of computers all over the world by creating a network of computers and making them operate as one. >>> Lectures are free and require no specialist knowledge. In french. 
 >>> By reservation only: tel. +41 (0)22 767 76 76

  17. SERI Biomass Program

    Science.gov (United States)

    Bergeron, P. W.; Corder, R. E.; Hill, A. M.; Lindsey, H.; Lowenstein, M. Z.

    1983-02-01

    The biomass with which this report is concerned includes aquatic plants, which can be converted into liquid fuels and chemicals; organic wastes (crop residues as well as animal and municipal wastes), from which biogas can be produced via anerobic digestion; and organic or inorganic waste streams, from which hydrogen can be produced by photobiological processes. The Biomass Program Office supports research in three areas which, although distinct, all use living organisms to create the desired products. The Aquatic Species Program (ASP) supports research on organisms that are themselves processed into the final products, while the Anaerobic Digestion (ADP) and Photo/Biological Hydrogen Program (P/BHP) deals with organisms that transform waste streams into energy products. The P/BHP is also investigating systems using water as a feedstock and cell-free systems which do not utilize living organisms. This report summarizes the progress and research accomplishments of the SERI Biomass Program during FY 1982.

  18. Dark matter cores all the way down

    Science.gov (United States)

    Read, J. I.; Agertz, O.; Collins, M. L. M.

    2016-07-01

    We use high-resolution simulations of isolated dwarf galaxies to study the physics of dark matter cusp-core transformations at the edge of galaxy formation: M200 = 107-109 M⊙. We work at a resolution (˜4 pc minimum cell size; ˜250 M⊙ per particle) at which the impact from individual supernovae explosions can be resolved, becoming insensitive to even large changes in our numerical `sub-grid' parameters. We find that our dwarf galaxies give a remarkable match to the stellar light profile; star formation history; metallicity distribution function; and star/gas kinematics of isolated dwarf irregular galaxies. Our key result is that dark matter cores of size comparable to the stellar half-mass radius r1/2 always form if star formation proceeds for long enough. Cores fully form in less than 4 Gyr for the M200 = 108 M⊙ and ˜14 Gyr for the 109 M⊙ dwarf. We provide a convenient two parameter `CORENFW' fitting function that captures this dark matter core growth as a function of star formation time and the projected stellar half-mass radius. Our results have several implications: (i) we make a strong prediction that if Λcold dark matter is correct, then `pristine' dark matter cusps will be found either in systems that have truncated star formation and/or at radii r > r1/2; (ii) complete core formation lowers the projected velocity dispersion at r1/2 by a factor of ˜2, which is sufficient to fully explain the `too-big-to-fail problem'; and (iii) cored dwarfs will be much more susceptible to tides, leading to a dramatic scouring of the sub-halo mass function inside galaxies and groups.

  19. Complex coacervate core micelles.

    Science.gov (United States)

    Voets, Ilja K; de Keizer, Arie; Cohen Stuart, Martien A

    2009-01-01

    In this review we present an overview of the literature on the co-assembly of neutral-ionic block, graft, and random copolymers with oppositely charged species in aqueous solution. Oppositely charged species include synthetic (co)polymers of various architectures, biopolymers - such as proteins, enzymes and DNA - multivalent ions, metallic nanoparticles, low molecular weight surfactants, polyelectrolyte block copolymer micelles, metallo-supramolecular polymers, equilibrium polymers, etcetera. The resultant structures are termed complex coacervate core/polyion complex/block ionomer complex/interpolyelectrolyte complex micelles (or vesicles); i.e., in short C3Ms (or C3Vs) and PIC, BIC or IPEC micelles (and vesicles). Formation, structure, dynamics, properties, and function will be discussed. We focus on experimental work; theory and modelling will not be discussed. Recent developments in applications and micelles with heterogeneous coronas are emphasized.

  20. Understanding core conductor fabrics

    Energy Technology Data Exchange (ETDEWEB)

    Swenson, D E, E-mail: deswenson@affinity-esd.com [Affinity Static Control Consulting, LLC 2609 Quanah Drive, Round Rock, Texas, 78681 (United States)

    2011-06-23

    ESD Association standard test method ANSI/ESD STM2.1 - Garments (STM2.1), provides electrical resistance test procedures that are applicable for materials and garments that have surface conductive or surface dissipative properties. As has been reported in other papers over the past several years{sup 1} fabrics are now used in many industries for electrostatic control purposes that do not have surface conductive properties and therefore cannot be evaluated using the procedures in STM2.1{sup 2}. A study was conducted to compare surface conductive fabrics with samples of core conductor fibre based fabrics in order to determine differences and similarities with regards to various electrostatic properties. This work will be used to establish a new work item proposal within WG-2, Garments, in the ESD Association Standards Committee in the USA.

  1. Transition Icons for Time Series Visualization and Exploratory Analysis.

    Science.gov (United States)

    Nickerson, Paul; Baharloo, Raheleh; Wanigatunga, Amal A; Manini, Todd D; Tighe, Patrick J; Rashidi, Parisa

    2017-05-16

    The modern healthcare landscape has seen the rapid emergence of techniques and devices which temporally monitor and record physiological signals. The prevalence of time series data within the healthcare field necessitates the development of methods which can analyze the data in order to draw meaningful conclusions. Time series behavior is notoriously difficult to intuitively understand due to its intrinsic high-dimensionality, which is compounded in the case of analyzing groups of time series collected from different patients. Our framework, which we call Transition Icons, renders common patterns in a visual format useful for understanding the shared behavior within groups of time series. Transition Icons are adept at detecting and displaying subtle differences and similarities e.g. between measurements taken from patients receiving different treatment strategies or stratified by demographics. We introduce various methods which collectively allow for exploratory analysis of groups of time series, while being free of distribution assumptions and including simple heuristics for parameter determination. Our technique extracts discrete transition patterns from Symbolic Aggregate approXimation (SAX) representations, and compiles transition frequencies into a Bag of Patterns (BoP) constructed for each group. These transition frequencies are normalized and aligned in icon form to intuitively display the underlying patterns. We demonstrate the Transition Icon technique for two time series data sets - postoperative pain scores, and hip-worn accelerometer activity counts. We believe Transition Icons can be an important tool for researchers approaching time series data, as they give rich and intuitive information about collective time series behaviors.

  2. Expectancies and Motivations to Attend an Informal Science Lecture Series

    Science.gov (United States)

    AbiGhannam, Niveen; Kahlor, LeeAnn; Dudo, Anthony; Liang, Ming-Ching; Rosenthal, Sonny; Banner, Jay L.

    2016-01-01

    This study explored the expectancies and motivations that prompt audiences to attend a university science lecture series. The series features talks by science experts from the host campus and around the USA. Each lecture typically attracts between 300 and 600 attendees, including middle and high school student groups, university students, and…

  3. An automated approach for annual layer counting in ice cores

    DEFF Research Database (Denmark)

    Winstrup, Mai; Svensson, A. M.; Rasmussen, S. O.;

    2012-01-01

    detection algorithm lies in the way it is able to imitate the manual procedures for annual layer counting, while being based on statistical criteria for annual layer identification. The most likely positions of multiple layer boundaries in a section of ice core data are determined simultaneously......, and a probabilistic uncertainty estimate of the resulting layer count is provided, ensuring an objective treatment of ambiguous layers in the data. Furthermore, multiple data series can be incorporated and used simultaneously. In this study, the automated layer counting algorithm has been applied to two ice core...

  4. An automated approach for annual layer counting in ice cores

    DEFF Research Database (Denmark)

    Winstrup, Mai; Svensson, A. M.; Rasmussen, S. O.;

    2012-01-01

    detection algorithm lies in the way it is able to imitate the manual procedures for annual layer counting, while being based on statistical criteria for annual layer identification. The most likely positions of multiple layer boundaries in a section of ice core data are determined simultaneously......, and a probabilistic uncertainty estimate of the resulting layer count is provided, ensuring an objective treatment of ambiguous layers in the data. Furthermore, multiple data series can be incorporated and used simultaneously. In this study, the automated layer counting algorithm has been applied to an ice core...

  5. Clinical value of core length in contemporary multicore prostate biopsy.

    Science.gov (United States)

    Lee, Sangchul; Jeong, Seong Jin; Hwang, Sung Il; Hong, Sung Kyu; Lee, Hak Jong; Byun, Seok Soo; Choe, Gheeyoung; Lee, Sang Eun

    2015-01-01

    There is little data about the clinical value of core length for prostate biopsy (PBx). We investigated the clinical values of various clinicopathological biopsy-related parameters, including core length, in the contemporary multi-core PBx. Medical records of 5,243 consecutive patients who received PBx at our institution were reviewed. Among them, 3,479 patients with prostate-specific antigen (PSA) ≤ 10 ng/ml level who received transrectal ultrasound (TRUS)-guided multi (≥ 12)-core PBx at our institution were analyzed for prostate cancer (PCa). Gleason score upgrading (GSU) was analyzed in 339 patients who were diagnosed with low-risk PCa and received radical prostatectomy. Multivariate logistic regression analyses for PCa detection and prediction of GSU were performed. The mean age and PSA of the entire cohort were 63.5 years and 5.4 ng/ml, respectively. The overall cancer detection rate was 28.5%. There was no statistical difference in core length between patients diagnosed with PCa and those without PCa (16.1 ± 1.8 vs 16.1 ± 1.9 mm, P = 0.945). The core length was also not significantly different (16.4 ± 1.7 vs 16.4 ± 1.6mm, P = 0.889) between the GSU group and non-GSU group. Multivariate logistic regression analyses demonstrated that the core length of PBx did not affect PCa detection in TRUS-guided multi-core PBx (P = 0.923) and was not prognostic for GSU in patients with low-risk PCa (P = 0.356). In patients undergoing contemporary multi-core PBx, core length may not have significant impact on PCa detection and also GSU following radical prostatectomy among low-risk PCa group.

  6. Clinical value of core length in contemporary multicore prostate biopsy.

    Directory of Open Access Journals (Sweden)

    Sangchul Lee

    Full Text Available There is little data about the clinical value of core length for prostate biopsy (PBx. We investigated the clinical values of various clinicopathological biopsy-related parameters, including core length, in the contemporary multi-core PBx.Medical records of 5,243 consecutive patients who received PBx at our institution were reviewed. Among them, 3,479 patients with prostate-specific antigen (PSA ≤ 10 ng/ml level who received transrectal ultrasound (TRUS-guided multi (≥ 12-core PBx at our institution were analyzed for prostate cancer (PCa. Gleason score upgrading (GSU was analyzed in 339 patients who were diagnosed with low-risk PCa and received radical prostatectomy. Multivariate logistic regression analyses for PCa detection and prediction of GSU were performed.The mean age and PSA of the entire cohort were 63.5 years and 5.4 ng/ml, respectively. The overall cancer detection rate was 28.5%. There was no statistical difference in core length between patients diagnosed with PCa and those without PCa (16.1 ± 1.8 vs 16.1 ± 1.9 mm, P = 0.945. The core length was also not significantly different (16.4 ± 1.7 vs 16.4 ± 1.6mm, P = 0.889 between the GSU group and non-GSU group. Multivariate logistic regression analyses demonstrated that the core length of PBx did not affect PCa detection in TRUS-guided multi-core PBx (P = 0.923 and was not prognostic for GSU in patients with low-risk PCa (P = 0.356.In patients undergoing contemporary multi-core PBx, core length may not have significant impact on PCa detection and also GSU following radical prostatectomy among low-risk PCa group.

  7. Group Anonymity

    CERN Document Server

    Chertov, Oleg; 10.1007/978-3-642-14058-7_61

    2010-01-01

    In recent years the amount of digital data in the world has risen immensely. But, the more information exists, the greater is the possibility of its unwanted disclosure. Thus, the data privacy protection has become a pressing problem of the present time. The task of individual privacy-preserving is being thoroughly studied nowadays. At the same time, the problem of statistical disclosure control for collective (or group) data is still open. In this paper we propose an effective and relatively simple (wavelet-based) way to provide group anonymity in collective data. We also provide a real-life example to illustrate the method.

  8. Effect of Core Training Program on Physical Functional Performance in Female Soccer Players

    Science.gov (United States)

    Taskin, Cengiz

    2016-01-01

    The purpose of this study was to determine the effect of core training program on speed, acceleration, vertical jump, and standing long jump in female soccer players. A total of 40 female soccer players volunteered to participate in this study. They were divided randomly into 1 of 2 groups: core training group (CTG; n = 20) and control group (CG;…

  9. Advances in core drilling technology

    Science.gov (United States)

    Holdsworth, G.

    Some notable technical advances in drill design were reported at the meeting, held in Canada August 30-September 1, 1982, at the University of Calgary. Chief amongst these was a battery powered, computer assisted electromechanical core drill which has recently been used by the Danes in Greenland to continuously core to the base of the ice sheet at 2038 m. This is the deepest coring operation so far on the Greenland ice sheet. (The record for deep glacier drilling is held by the U.S. Army Cold Regions Research and Engineering Laboratory for the continuous coring through 2164 m of ice to bedrock at Byrd Station, Antarctica, in 1968). In early 1982, a current Soviet core drilling operation was reported to be at a depth of 2000 m at Vostok station, Antarctica, where the total ice thickness is about 4000 m; the goal of core drilling the entire ice thickness there could be achieved before the end of 1983.

  10. STEAM GENERATOR GROUP PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    Clark, R. A.; Lewis, M

    1985-09-01

    This report is a summary of progress in the Surry Steam Generator Group Project for 1984. Information is presented on the analysis of two baseline eddy current inspections of the generator. Round robin series of tests using standard in-service inspection techniques are described along with some preliminary results. Observations are reported of degradation found on tubing specimens removed from the generator, and on support plates characterized in-situ. Residual stresses measured on a tubing specimen are reported. Two steam generator repair demonstrations are described; one for antivibration bar replacement, and one on tube repair methods. Chemical analyses are shown for sludge samples removed from above the tube sheet.

  11. Groups and symmetry

    CERN Document Server

    Farmer, David W

    1995-01-01

    In most mathematics textbooks, the most exciting part of mathematics-the process of invention and discovery-is completely hidden from the reader. The aim of Groups and Symmetry is to change all that. By means of a series of carefully selected tasks, this book leads readers to discover some real mathematics. There are no formulas to memorize; no procedures to follow. The book is a guide: Its job is to start you in the right direction and to bring you back if you stray too far. Discovery is left to you. Suitable for a one-semester course at the beginning undergraduate level, there are no prerequ

  12. Notes on quantum groups

    Energy Technology Data Exchange (ETDEWEB)

    Pressley, A.; Chari, V. (King' s Coll., London (UK). Dept. of Mathematics Tata Inst. of Fundamental Research, Bombay (India). School of Mathematics)

    1990-12-01

    The authors presents an introduction to quantum groups defined as a deformation of the universal enveloping algebra of a Lie algebra. After the description of Hopf algebras with some examples the approach of Drinfel'd and Jimbo is described, where the quantization of a Lie algebra represents a Hopf algebra, defined over the algebra of formal power series in an indetermined h. The authors show that this approach arises from a r-matrix, which satisfies the classical Yang-Baxter equation. As example quantum sl{sub 2} is considered. Furthermore the approaches of Manin and Woroniwicz and the R-matrix approach are described. (HSI).

  13. Informal groups

    NARCIS (Netherlands)

    E. van den Berg; P. van Houwelingen; J. de Hart

    2011-01-01

    Original title: Informele groepen Going out running with a group of friends, rather than joining an official sports club. Individuals who decide to take action themselves rather than giving money to good causes. Maintaining contact with others not as a member of an association, but through an Inter

  14. The impact of core length on prostate cancer diagnosis during a standard 14-core prostate biopsy scheme.

    Science.gov (United States)

    Dell'Atti, Lucio; Ippolito, Carmelo

    2016-11-18

    Even if many studies in the literature purposed to evaluate the improvement of the prostate biopsy (PBx), few studies assessed the diagnostic value of core length in PBx. In this study, we evaluated the length of needle cores sampled during transrectal PBx (TRUSBx) and its impact on cancer diagnosis in a standard 14-core scheme. Medical records of 573 patients who underwent an initial TRUSBx with 14-cores scheme for suspicious prostate cancer (PCa) at our Department were reviewed. The PBx procedure and pathological evaluation were standardized. Cores lengths were compared in patients with versus without cancer, and were divided into group A and B, respectively. Statistical analysis was done to define an acceptable cut-off for biopsy length. The mean age of the entire cohort was 62.1 ± 7.2 years, while median total prostate-specific antigen (PSA) and prostate volume were 4.2 ng/ml and 44.7 ml, respectively. PCa was showed in 33.3% of patients. Mean core length in group A versus B was 11.9 ± 3.9 versus 11.1 ± 3.2 mm (p = 0.016). Thus, core lengths were significantly longer in patients with cancer. There were no statistically significant differences when we considered the whole length of cores sampled from the right lobe (p = 0.58) and left lobe (p = 0.34). The cancer detection rates in cores may be increased by core length in PCa patients during a TRUSBx. Our results suggest a core length of greater than 11.8 mm as a cut-off for quality warranty.

  15. Cross recurrence plot based synchronization of time series

    Directory of Open Access Journals (Sweden)

    N. Marwan

    2002-01-01

    Full Text Available The method of recurrence plots is extended to the cross recurrence plots (CRP which, among others, enables the study of synchronization or time differences in two time series. This is emphasized in a distorted main diagonal in the cross recurrence plot, the line of synchronization (LOS. A non-parametrical fit of this LOS can be used to rescale the time axis of the two data series (whereby one of them is compressed or stretched so that they are synchronized. An application of this method to geophysical sediment core data illustrates its suitability for real data. The rock magnetic data of two different sediment cores from the Makarov Basin can be adjusted to each other by using this method, so that they are comparable.

  16. Cross Recurrence Plot Based Synchronization of Time Series

    CERN Document Server

    Marwan, N; Nowaczyk, N R

    2002-01-01

    The method of recurrence plots is extended to the cross recurrence plots (CRP), which among others enables the study of synchronization or time differences in two time series. This is emphasized in a distorted main diagonal in the cross recurrence plot, the line of synchronization (LOS). A non-parametrical fit of this LOS can be used to rescale the time axis of the two data series (whereby one of it is e.g. compressed or stretched) so that they are synchronized. An application of this method to geophysical sediment core data illustrates its suitability for real data. The rock magnetic data of two different sediment cores from the Makarov Basin can be adjusted to each other by using this method, so that they are comparable.

  17. The DLESE Evaluation Core Services Project

    Science.gov (United States)

    Buhr, S. M.; Barker, L. J.; Reeves, T. C.

    2003-12-01

    The DLESE Evaluation Core Service project will conduct evaluation of DLESE and provide evaluation consultation, resources and services to the DLESE community. Through this work we anticipate that we will learn more about the impact and use of digital libraries, and will promote an evaluation mindset within the geoscience education community. Activities of the DLESE Evaluation Service team include 1) evaluation planning for and of DLESE, 2) conducting formative evaluation of DLESE (user needs, data access, collections, outreach), 3) conducting classroom evaluation of DLESE use on teaching practices and learning outcomes, and 4) collection, synthesis, and reporting of evaluation findings garnered from all core teams and major projects. Many opportunities for community involvement exist. A strand group convened during the 2004 DLESE Annual Meeting took DLESE Evaluation as their topic, provided recommendations and will continue their activities through the year. The related Evaluation Toolkit collection is now discoverable through DLESE, and upcoming activities of all the core teams will provide evaluation opportunities to be described. Other community opportunities include consulting with Evaluation Service for education grant proposals, attending an evaluation workshop,and applying for an Evaluation Minigrant (up to \\$5K per award) Progress to date will be discussed, the Evaluation Core Services team members will be introduced, and plans and opportunities will be described in more detail.

  18. Core TuLiP

    OpenAIRE

    Czenko, M.R.; Etalle, Sandro

    2007-01-01

    We propose CoreTuLiP - the core of a trust management language based on Logic Programming. CoreTuLiP is based on a subset of moded logic programming, but enjoys the features of TM languages such as RT; in particular clauses are issued by different authorities and stored in a distributed manner. We present a lookup and inference algorithm which we prove to be correct and complete w.r.t. the declarative semantics. CoreTuLiP enjoys uniform syntax and the well-established semantics and is express...

  19. Biochemistry Instrumentation Core Technology Center

    Data.gov (United States)

    Federal Laboratory Consortium — The UCLA-DOE Biochemistry Instrumentation Core Facility provides the UCLA biochemistry community with easy access to sophisticated instrumentation for a wide variety...

  20. Aqua/Aura Spring 2017 Inclination Adjust Maneuver Series

    Science.gov (United States)

    Noyes, Thomas; Stezelberger, Shane

    2017-01-01

    This will be presented at the International Earth Science Constellation Mission Operations Working Group meeting June 13-15, 2017 to discuss the AquaAura Spring 2017 Inclination Adjust Maneuver series.