WorldWideScience

Sample records for group catalogue g3cv1

  1. The new OGC Catalogue Services 3.0 specification - status of work

    Science.gov (United States)

    Bigagli, Lorenzo; Voges, Uwe

    2013-04-01

    We report on the work of the Open Geospatial Consortium Catalogue Services 3.0 Standards Working Group (OGC Cat 3.0 SWG for short), started in March 2008, with the purpose to process change requests on the Catalogue Services 2.0.2 Implementation Specification (OGC 07-006r1) and produce a revised version thereof, comprising the related XML schemas and abstract test suite. The work was initially intended as a minor revision (version 2.1), but later retargeted as a major update of the standard and rescheduled (the anticipated roadmap ended in 2008). The target audience of Catalogue Services 3.0 includes: • Implementors of catalogue services solutions. • Designers and developers of catalogue services profiles. • Providers/users of catalogue services. The two main general areas of enhancement included: restructuring the specification document according to the OGC standard for modular specifications (OGC 08-131r3, also known as Core and Extension model); incorporating the current mass-market technologies for discovery on the Web, namely OpenSearch. The document was initially split into four parts: the general model and the three protocol bindings HTTP, Z39.50, and CORBA. The CORBA binding, which was very rarely implemented, and the Z39.50 binding have later been dropped. Parts of the Z39.50 binding, namely Search/Retrieve via URL (SRU; same semantics as Z39.50, but stateless), have been provided as a discussion paper (OGC 12-082) for possibly developing a future SRU profile. The Catalogue Services 3.0 specification is structured as follows: • Part 1: General Model (Core) • Part 2: HTTP Protocol Binding (CSW) In CSW, the GET/KVP encoding is mandatory. The POST/XML encoding is optional. SOAP is supported as a special case of the POST/XML encoding. OpenSearch must always be supported, regardless of the implemented profiles, along with the OpenSearch Geospatial and Temporal Extensions (OGC 10-032r2). The latter specifies spatial (e.g. point-plus-radius, bounding

  2. Dark Energy Survey Year 1 Results: Weak Lensing Shape Catalogues

    Energy Technology Data Exchange (ETDEWEB)

    Zuntz, J.; et al.

    2017-08-04

    We present two galaxy shape catalogues from the Dark Energy Survey Year 1 data set, covering 1500 square degrees with a median redshift of $0.59$. The catalogues cover two main fields: Stripe 82, and an area overlapping the South Pole Telescope survey region. We describe our data analysis process and in particular our shape measurement using two independent shear measurement pipelines, METACALIBRATION and IM3SHAPE. The METACALIBRATION catalogue uses a Gaussian model with an innovative internal calibration scheme, and was applied to $riz$-bands, yielding 34.8M objects. The IM3SHAPE catalogue uses a maximum-likelihood bulge/disc model calibrated using simulations, and was applied to $r$-band data, yielding 21.9M objects. Both catalogues pass a suite of null tests that demonstrate their fitness for use in weak lensing science. We estimate the 1$\\sigma$ uncertainties in multiplicative shear calibration to be $0.013$ and $0.025$ for the METACALIBRATION and IM3SHAPE catalogues, respectively.

  3. IAEA Catalogue of Services for Nuclear Infrastructure Development. Rev. 1, April 2014

    International Nuclear Information System (INIS)

    2014-04-01

    This IAEA Catalogue offers a wide range of services to Member States embarking on a new nuclear power programme or expanding an existing one. A new IAEA Catalogue of Services for Nuclear Infrastructure Development helps Member States to identify and request IAEA assistance for national organizations at different stages of the development or expansion of a nuclear power programme. This IAEA Catalogue of Services is presented in two tables. It is based on the IAEA Milestones Approach for nuclear power infrastructure development, documented in 'Milestones in the Development of a National Infrastructure for Nuclear Power' (IAEA Nuclear Energy Series NG-G-3.1). The two tables allow users to identify and select available IAEA services by: i) The three phases of the IAEA Milestones Approach, or ii) Organizations typically involved in the development of a nuclear power programme: the government / Nuclear Energy Programme Implementing Organization (NEPIO), the regulatory body and the owner operator of a nuclear power plant. This Catalogue includes information on the following IAEA services: i) Workshops / Training Courses; ii) Expert Missions / Advisory Services; iii) Review Missions / Peer Reviews; iv) Training tools and networks. The Catalogue lists both existing IAEA services and those being developed for the 19 issues to be addressed in developing a national nuclear infrastructure. Each existing service is linked to a relevant IAEA webpage that either describes a particular service or gives practical examples of the type of assistance that the Agency offers (e.g. workshops or missions). The owners of these webpages can be contacted for more detailed information or to request assistance. This IAEA Catalogue of Services will be updated regularly

  4. TENCompetence Learning Design Toolkit, Runtime component, ccsi_v3_2_10c_v1_4

    NARCIS (Netherlands)

    Sharples, Paul; Popat, Kris; Llobet, Lau; Santos, Patricia; Hernández-Leo, Davinia; Miao, Yongwu; Griffiths, David; Beauvoir, Phillip

    2010-01-01

    Sharples, P., Popat, K., Llobet, L., Santos, P., Hernandez-Leo, D., Miao, Y., Griffiths, D. & Beauvoir, P. (2009) TENCompetence Learning Design Toolkit, Runtime component, ccsi_v3_2_10c_v1_4 This release is composed of three files corresponding to CopperCore Service Integration (CCSI) v3.2-10cv1.4,

  5. Derivation of photometric redshifts for the 3XMM catalogue

    Science.gov (United States)

    Georgantopoulos, I.; Corral, A.; Mountrichas, G.; Ruiz, A.; Masoura, V.; Fotopoulou, S.; Watson, M.

    2017-10-01

    We present the results from our ESA Prodex project that aims to derive photometric redshifts for the 3XMM catalogue. The 3XMM DR-6 offers the largest X-ray survey, containing 470,000 unique sources over 1000 sq. degrees. We cross-correlate the X-ray positions with optical and near-IR catalogues using Bayesian statistics. The optical catalogue used so far is the SDSS while currently we are employing the recently released PANSTARRS catalogue. In the near IR we use the Viking, VHS, UKIDS surveys and also the WISE W1 and W2 filters. The estimation of photometric redshifts is based on the TPZ software. The training sample is based on X-ray selected samples with available SDSS spectroscopy. We present here the results for the 40,000 3XMM sources with available SDSS counterparts. Our analysis provides very reliable photometric redshifts with sigma(mad)=0.05 and a fraction of outliers of 8% for the optically extended sources. We discuss the wide range of applications that are feasible using this unprecedented resource.

  6. A global catalogue of Ceres impact craters ≥ 1 km and preliminary analysis

    Science.gov (United States)

    Gou, Sheng; Yue, Zongyu; Di, Kaichang; Liu, Zhaoqin

    2018-03-01

    The orbital data products of Ceres, including global LAMO image mosaic and global HAMO DTM with a resolution of 35 m/pixel and 135 m/pixel respectively, are utilized in this research to create a global catalogue of impact craters with diameter ≥ 1 km, and their morphometric parameters are calculated. Statistics shows: (1) There are 29,219 craters in the catalogue, and the craters have a various morphologies, e.g., polygonal crater, floor fractured crater, complex crater with central peak, etc.; (2) The identifiable smallest crater size is extended to 1 km and the crater numbers have been updated when compared with the crater catalogue (D ≥ 20 km) released by the Dawn Science Team; (3) The d/D ratios for fresh simple craters, obviously degraded simple crater and polygonal simple crater are 0.11 ± 0.04, 0.05 ± 0.04 and 0.14 ± 0.02 respectively. (4) The d/D ratios for non-polygonal complex crater and polygonal complex crater are 0.08 ± 0.04 and 0.09 ± 0.03. The global crater catalogue created in this work can be further applied to many other scientific researches, such as comparing d/D with other bodies, inferring subsurface properties, determining surface age, and estimating average erosion rate.

  7. Comparison of Different Compression to Ventilation Ratios (2: 1, 3: 1, and 4: 1) during Cardiopulmonary Resuscitation in a Porcine Model of Neonatal Asphyxia.

    Science.gov (United States)

    Pasquin, Matteo P; Cheung, Po-Yin; Patel, Sparsh; Lu, Min; Lee, Tze-Fun; Wagner, Michael; O'Reilly, Megan; Schmölzer, Georg M

    2018-04-12

    High-quality chest compression is essential during neonatal cardiopulmonary resuscitation (CPR). However, the optimal compression to ventilation ratio (C:V) that should be used during neonatal CPR to optimize coronary and cerebral perfusion while providing adequate ventilation remains unknown. We hypothesized that different C:V ratios (e.g., 2: 1 or 4: 1) will reduce the time to return of spontaneous circulation (ROSC) in severely asphyxiated piglets. Thirty-one newborn piglets (1-4 days old) were anesthetized, intubated, instrumented, and exposed to 50-min normocapnic hypoxia followed by asphyxia. Piglets were randomized into 4 groups: 2: 1 (n = 8), 3: 1 (n = 8), 4: 1 (n = 8) C:V ratio, or a sham group (n = 7). Cardiac function, carotid blood flow, cerebral oxygenation, and respiratory parameters were continuously recorded throughout the experiment. Thirty-one piglets were included in the study, and there was no difference in the duration of asphyxia or the degree of asphyxiation (as indicated by pH, PaCO2, and lactate) among the different groups. The median (IQR) time to ROSC was similar between the groups with 127 (82-210), 96 (88-126), and 119 (83-256) s in the 2: 1, 3: 1, and 4: 1 C:V ratio groups, respectively (p = 0.67 between groups). Similarly, there was no difference in 100% oxygen requirement or epinephrine administration between the experimental groups. Different C:V ratios resulted in similar ROSC, mortality, oxygen, and epinephrine administration during resuscitation in a porcine model of neonatal asphyxia. © 2018 S. Karger AG, Basel.

  8. Cataloguing outside the box a practical guide to cataloguing special collections materials

    CERN Document Server

    Falk, Patricia

    2010-01-01

    A practical guide to cataloguing and processing the unique special collections formats in the Browne Popular Culture Library (BPCL) and the Music Library and Sound Recordings Archives (MLSRA) at Bowling Green State University (BGSU) (e.g. fanzines, popular sound recordings, comic books, motion picture scripts and press kits, popular fiction). Cataloguing Outside the Box provides guidance to professionals in library and information science facing the same cataloguing challenges. Additionally, name authority work for these collections is addressed.provides practical guidelines and solutions for

  9. Identification and expression analysis of four 14-3-3 genes during fruit ripening in banana (Musa acuminata L. AAA group, cv. Brazilian).

    Science.gov (United States)

    Li, Mei-Ying; Xu, Bi-Yu; Liu, Ju-Hua; Yang, Xiao-Liang; Zhang, Jian-Bin; Jia, Cai-Hong; Ren, Li-Cheng; Jin, Zhi-Qiang

    2012-02-01

    To investigate the regulation of 14-3-3 proteins in banana (Musa acuminata L. AAA group, cv. Brazilian) fruit postharvest ripening, four cDNAs encoding 14-3-3 proteins were isolated from banana and designated as Ma-14-3-3a, Ma-14-3-3c, Ma-14-3-3e, and Ma-14-3-3i, respectively. Amino acid sequence alignment showed that the four 14-3-3 proteins shared a highly conserved core structure and variable C-terminal as well as N-terminal regions with 14-3-3 proteins from other plant species. Phylogenetic analysis revealed that the four 14-3-3 genes belong to the non-ε groups. They were differentially and specifically expressed in various tissues. Real-time RT-PCR analysis indicated that these four genes function differentially during banana fruit postharvest ripening. Three genes, Ma-14-3-3a, Ma-14-3-3c, and Ma-14-3-3e, were significantly induced by exogenous ethylene treatment. However, gene function differed in naturally ripened fruits. Ethylene could induce Ma-14-3-3c expression during postharvest ripening, but expression patterns of Ma-14-3-3a and Ma-14-3-3e suggest that these two genes appear to be involved in regulating ethylene biosynthesis during fruit ripening. No obvious relationship emerged between Ma-14-3-3i expression in naturally ripened and 1-MCP (1-methylcyclopropene)-treated fruit groups during fruit ripening. These results indicate that the 14-3-3 proteins might be involved in various regulatory processes of banana fruit ripening. Further studies will mainly focus on revealing the detailed biological mechanisms of these four 14-3-3 genes in regulating banana fruit postharvest ripening.

  10. M3.2.3 Personas Catalogue

    DEFF Research Database (Denmark)

    Guldbæk Rasmussen, Katja; Iversen, Rie; Petersen, Gitte

    This catalogue contains 7 personas developed for use in the Europeana projects. The premise of this work has been to find already existing personas within the domains of archives, museums and libraries in Europe. These have then been pared down to their essentials and rebuilt, using input from...... Europeana partners and research on behavior and search patterns. If you have never worked with personas before,please take the time to read the short introduction in the chapter about method. The personas, and a brief “How To” is the central issue in this catalogue and therefore placed at the front....... For those wanting to dig a little deeper into how the personas were created, more in-depth material can be found in the chapters at the back....

  11. Gaia Data Release 1. Catalogue validation

    NARCIS (Netherlands)

    Arenou, F.; Luri, X.; Babusiaux, C.; Fabricius, C.; Helmi, A.; Robin, A. C.; Vallenari, A.; Blanco-Cuaresma, S.; Cantat-Gaudin, T.; Findeisen, K.; Reylé, C.; Ruiz-Dern, L.; Sordo, R.; Turon, C.; Walton, N. A.; Shih, I.-C.; Antiche, E.; Barache, C.; Barros, M.; Breddels, M.; Carrasco, J. M.; Costigan, G.; Diakité, S.; Eyer, L.; Figueras, F.; Galluccio, L.; Heu, J.; Jordi, C.; Krone-Martins, A.; Lallement, R.; Lambert, S.; Leclerc, N.; Marrese, P. M.; Moitinho, A.; Mor, R.; Romero-Gómez, M.; Sartoretti, P.; Soria, S.; Soubiran, C.; Souchay, J.; Veljanoski, J.; Ziaeepour, H.; Giuffrida, G.; Pancino, E.; Bragaglia, A.

    Context. Before the publication of the Gaia Catalogue, the contents of the first data release have undergone multiple dedicated validation tests. Aims: These tests aim to provide in-depth analysis of the Catalogue content in order to detect anomalies and individual problems in specific objects or in

  12. Isolation and characterization of a virus (CvV-BW1 that infects symbiotic algae of Paramecium bursaria in Lake Biwa, Japan

    Directory of Open Access Journals (Sweden)

    Kasahara Masahiro

    2010-09-01

    Full Text Available Abstract Background We performed an environmental study of viruses infecting the symbiotic single-celled algae of Paramecium bursaria (Paramecium bursaria Chlorella virus, PBCV in Lake Biwa, the largest lake in Japan. The viruses detected were all Chlorella variabilis virus (CvV = NC64A virus. One of them, designated CvV-BW1, was subjected to further characterization. Results CvV-BW1 formed small plaques and had a linear DNA genome of 370 kb, as judged by pulsed-field gel electrophoresis. Restriction analysis indicated that CvV-BW1 DNA belongs to group H, one of the most resistant groups among CvV DNAs. Based on a phylogenetic tree constructed using the dnapol gene, CvV was classified into two clades, A and B. CvV-BW1 belonged to clade B, in contrast to all previously identified virus strains of group H that belonged to clade A. Conclusions We conclude that CvV-BW1 composes a distinct species within C. variabilis virus.

  13. VizieR Online Data Catalog: Catalogue of features in the S4G (Herrera-Endoqui+, 2015)

    Science.gov (United States)

    Herrera-Endoqui, M.; Diaz-Garcia, S.; Laurikainen, E.; Salo, H.

    2015-08-01

    Table 2 contains the properties of bars, ring- and lens-structures in the S4G. Data for bars contains the visual estimated barlength, the maximum ellipticity in the bar region, the visual estimated position angle, and the barlength obtained from the ellipticity maximum. They are given in both the sky plane and the disk plane, the conversion is made using P4 orientation parameters (Salo et al., 2015ApJS..219....4S; Table 1). For bars the disk plane values are given only when a reliable ellipticity maximum was found and the galaxy inclination i<65 deg. For other features the parameters are obtained from fitting ellipses to points tracing the structure. A quality flag for our measurement is also given: 1 indicates a good fit and unambiguously identified feature, 2 indicates a hard to trace feature, 3 indicates an uncertain feature identification (due to high inclination of host galaxy or incomplete feature). Table 3 contains the properties of spiral arms in the S4G. Type of spiral arms, the pitch angle, the inner and the outer radius are given for every spiral segment (see the catalogue web page). The type of spiral arms are taken from Buta et al. (2015ApJS..217...32B, Cat. J/ApJS/217/32): G for grand design, M for multiple, and F for flocculent spiral arms. Our estimation of the quality of the fit is also given (1.0 = good; 2.0 = acceptable). (2 data files).

  14. Illumination dependence of I-V and C-V characterization of Au/InSb/InP(1 0 0) Schottky structure

    International Nuclear Information System (INIS)

    Akkal, B.; Benamara, Z.; Bouiadjra, N. Bachir; Tizi, S.; Gruzza, B.

    2006-01-01

    The effects of surface preparation and illumination on electric parameters of Au/InSb/InP(100) Schottky diode were investigated, in the later diode InSb forms a fine restructuration layer allowing to block In atoms migration to surface. In order to study the electric characteristics under illumination, we make use of an He-Ne laser of 1 mW power and 632.8 nm wavelength. The current-voltage I(V G ), the capacitance-voltage C(V G ) measurements were plotted and analysed. The saturation current I s , the serial resistance R s and the mean ideality factor n are, respectively, equal to 2.03 x 10 -5 A, 85 Ω, 1.7 under dark and to 3.97 x 10 -5 A, 67 Ω, 1.59 under illumination. The analysis of I(V G ) and C(V G ) characteristics allows us to determine the mean interfacial state density N ss and the transmission coefficient θ n equal, respectively, to 4.33 x 10 12 eV -1 cm -2 , 4.08 x 10 -3 under dark and 3.79 x 10 12 eV -1 cm -2 and 5.65 x 10 -3 under illumination. The deep discrete donor levels presence in the semiconductor bulk under dark and under illumination are responsible for the non-linearity of the C -2 (V G ) characteristic

  15. EN-CV during LS1: upgrade, consolidation, maintenance, operation

    International Nuclear Information System (INIS)

    Nonis, M.

    2012-01-01

    The Cooling and Ventilation (CV) Group in the Engineering Department (EN) will be heavily involved in several projects and activities during the long shutdown in 2013 and 2014 (LS1) within a time-frame limited to around twelve months. According to the requests received so far, most projects are related to the upgrade of users' equipment, consolidation work, and the construction of new plants. However, through the experience gained from the first years of the LHC run, some projects are also needed to adapt the existing installations to the new operating parameters. Some of these projects are presented hereafter, outlining the impact that they will have on operational working conditions or risks of breakdown. Among these projects we find: the PM32 raising pumps, the cooling of the CERN Control Center, R2E, the backup cooling towers for ATLAS and cryogenics, a thermosyphon for ATLAS, or new pumps in UWs. Finally, EN-CV activities during LS1 for maintenance, operation, and commissioning will be mentioned since they represent a major workload for the Group

  16. VIRAC: the VVV Infrared Astrometric Catalogue

    Science.gov (United States)

    Smith, L. C.; Lucas, P. W.; Kurtev, R.; Smart, R.; Minniti, D.; Borissova, J.; Jones, H. R. A.; Zhang, Z. H.; Marocco, F.; Contreras Peña, C.; Gromadzki, M.; Kuhn, M. A.; Drew, J. E.; Pinfield, D. J.; Bedin, L. R.

    2018-02-01

    We present VIRAC version 1, a near-infrared proper motion and parallax catalogue of the VISTA Variables in the Via Lactea (VVV) survey for 312 587 642 unique sources averaged across all overlapping pawprint and tile images covering 560 deg2 of the bulge of the Milky Way and southern disc. The catalogue includes 119 million high-quality proper motion measurements, of which 47 million have statistical uncertainties below 1 mas yr-1. In the 11 stars and brown dwarfs, subdwarfs, white dwarfs) and kinematic distance measurements of young stellar objects. Nearby objects discovered include LTT 7251 B, an L7 benchmark companion to a G dwarf with over 20 published elemental abundances, a bright L subdwarf, VVV 1256-6202, with extremely blue colours and nine new members of the 25 pc sample. We also demonstrate why this catalogue remains useful in the era of Gaia. Future versions will be based on profile fitting photometry, use the Gaia absolute reference frame and incorporate the longer time baseline of the VVV extended survey.

  17. Molecular mapping of powdery mildew resistance gene Eg-3 in cultivated oat (Avena sativa L. cv. Rollo).

    Science.gov (United States)

    Mohler, Volker; Zeller, Friedrich J; Hsam, Sai L K

    2012-05-01

    Powdery mildew is a prevalent fungal disease affecting oat (Avena sativa L.) production in Europe. Common oat cultivar Rollo was previously shown to carry the powdery mildew resistance gene Eg-3 in common with cultivar Mostyn. The resistance gene was mapped with restriction fragment length polymorphism (RFLP) markers from Triticeae group-1 chromosomes using a population of F(3) lines from a cross between A. byzantina cv. Kanota and A. sativa cv. Rollo. This comparative mapping approach positioned Eg-3 between cDNA-RFLP marker loci cmwg706 and cmwg733. Since both marker loci were derived from the long arm of barley chromosome 1H, the subchromosomal location of Eg-3 was assumed to be on the long arm of oat chromosome 17. Amplified fragment length polymorphism (AFLP) marker technology featured as an efficient means for obtaining markers closely linked to Eg-3.

  18. No-horizon theorem for spacetimes with spacelike G{sub 1} isometry groups

    Energy Technology Data Exchange (ETDEWEB)

    Goncalves, Sergio M C V [Department of Physics, Yale University, New Haven, CT 06511 (United States)

    2003-12-21

    We consider four-dimensional spacetimes (M, g) which obey the Einstein equations G = T and admit a global spacelike G{sub 1} = R isometry group. By means of dimensional reduction and local analysis on the reduced (2 + 1) spacetime, we obtain a sufficient condition on T which guarantees that (M, g) cannot contain apparent horizons. Given any (3 + 1) spacetime with spacelike translational isometry, the no-horizon condition can be readily tested without the need for dimensional reduction. This provides thus a useful and encompassing apparent horizon test for G{sub 1}-symmetric spacetimes. We argue that this adds further evidence towards the validity of the hoop conjecture and signals possible (albeit arguably unlikely) violations of strong cosmic censorship.

  19. 3CV+2: modelo de calidad para la construcción de la vivienda 3CV+2: quality model for dwelling construction

    Directory of Open Access Journals (Sweden)

    Salvador García Rodríguez

    2008-08-01

    Full Text Available Este artículo presenta el modelo y los resultados que, desde Junio de 2005, se han alcanzado en el desarrollo del Programa Nacional de Certificación de los Procesos Constructivos de la Vivienda en base al Modelo 3cv+2. El programa se ha desarrollado con base a un convenio entre el Tecnológico de Monterrey y la Cámara Nacional de la Industria de Desarrollo y Promoción de Vivienda. Actualmente se encuentran voluntariamente en el programa 52 empresas inmobiliarias de diferentes estados de la República Mexicana. El modelo de calidad 3cv+2 es una metodología que busca establecer en los niveles operativos de la construcción criterios que permitan reducir la variabilidad del proceso de construcción, y además permita de manera sistemática, y en un proceso de mejora continua, evaluar el desempeño de calidad en proyectos de construcción de vivienda. El modelo 3cv+2 define en su nombre el alcance del mismo, 3 criterios de calidad para la vivienda (insumos, proceso y producto, apoyado por 2 auditorías (+2, la auditoría interna de la propia empresa, mas la auditoría externa hecha por el Tecnológico de Monterrey. El modelo 3cv+2 busca garantizar que los insumos utilizados en la construcción de las viviendas sean de calidad superior, y que los procesos de ejecución posean características de calidad, productividad, eficiencia, racionalización, y estandarización; de tal manera que insumos y productos sean de alto valor agregado, y garanticen la calidad especificada en las etapas parciales y en la vivienda terminada.This paper presents the model and the results that have been achieved during the development of the National Quality Certification Program based on the model 3cv +2 from June 2005. This program has been developed based on an agreement between the Monterrey Tech and the National Chamber of Housing Industry. Nowadays, the program has 52 voluntary real estate companies from different states of Mexico. The 3cv+2 quality model is a

  20. CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Terra-FM1_Edition1-CV)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2006-11-02] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

  1. Dark Energy Survey Year 1 Results: galaxy mock catalogues for BAO

    Energy Technology Data Exchange (ETDEWEB)

    Avila, S.; et al.

    2017-12-17

    Mock catalogues are a crucial tool in the analysis of galaxy surveys data, both for the accurate computation of covariance matrices, and for the optimisation of analysis methodology and validation of data sets. In this paper, we present a set of 1800 galaxy mock catalogues designed to match the Dark Energy Survey Year-1 BAO sample (Crocce et al. 2017) in abundance, observational volume, redshift distribution and uncertainty, and redshift dependent clustering. The simulated samples were built upon HALOGEN (Avila et al. 2015) halo catalogues, based on a $2LPT$ density field with an exponential bias. For each of them, a lightcone is constructed by the superposition of snapshots in the redshift range $0.451.4$. Uncertainties introduced by so-called photometric redshifts estimators were modelled with a \\textit{double-skewed-Gaussian} curve fitted to the data. We also introduce a hybrid HOD-HAM model with two free parameters that are adjusted to achieve a galaxy bias evolution $b(z_{\\rm ph})$ that matches the data at the 1-$\\sigma$ level in the range $0.61.0$. We further analyse the galaxy mock catalogues and compare their clustering to the data using the angular correlation function $ w(\\theta)$, the comoving transverse separation clustering $\\xi_{\\mu<0.8}(s_{\\perp})$ and the angular power spectrum $C_\\ell$.

  2. C-V and G-V characteristics of ion-implanted MOS structures depending upon the geometrical structure of the implanted region

    International Nuclear Information System (INIS)

    Zohta, Y.

    1977-01-01

    It is found that the capacitance-voltage (C-V) and conductance-voltage (G-V) characteristics of MOS capacitors, into which ions of the opposite conductivity type are implanted, depend strongly upon the geometrical structure of the ion-implanted region. This phenomenon can be analyzed in terms of lateral current flow which connects an inversion layer formed in the ion-implanted region to a surrounding nonimplanted substrate. On the basis of this model, the C-V and G-V characteristics are calculated using a simple equivalent circuit, and general relationships inherent in this model are obtained. MOS capacitors with an ion-implanted layer of different geometries have been prepared to measure their C-V and G-V characteristics. Comparison of experimental measurements with theory substantiates the lateral current flow model

  3. Canine Circovirus 1 (CaCV-1) and Canine Parvovirus 2 (CPV-2): Recurrent Dual Infections in a Papillon Breeding Colony.

    Science.gov (United States)

    Thaiwong, T; Wise, A G; Maes, R K; Mullaney, T; Kiupel, M

    2016-11-01

    Recurrent outbreaks of sudden death and bloody diarrhea were reported in March 2013 and February 2014 in a breeding colony of Papillon dogs. During the first outbreak, 1 adult dog and 2 eight-month-old puppies died. During the second outbreak, 2 ten-week-old puppies died. One puppy from the first outbreak and 2 puppies from the second outbreak were examined at necropsy. Histologically, all 3 puppies had severe segmental crypt necrosis of the small intestine and marked lymphoid follicle depletion in the spleen and Peyer's patches. Real-time (RT) polymerase chain reaction (PCR) demonstrated abundant canine parvovirus (CPV-2) DNA (Ctcanine circovirus 1 (CaCV-1). Very high levels of CaCV-1 DNA (Ct<13) were detected in small intestine, lymph nodes, and spleen. In situ hybridization for CaCV-1 detected rare positive nuclei of regenerating crypt epithelium but abundant amounts of CaCV-1 nucleic acid in the cytoplasm and nuclei of histiocytes in all lymphoid tissues, including granulomatous inflammatory foci and hepatic Kupffer cells. Significant levels of CaCV-1 DNA were detected in blood and serum (Ct as low as 13) but not feces from 3 surviving dogs at 2 months or 1 year after the outbreak, respectively. We hypothesize that CPV-2 infection predisposed dogs to CaCV-1 infection and ultimately resulted in more severe clinical disease. © The Author(s) 2016.

  4. CERES ERBE-like Monthly Regional Averages (ES-9) in HDF ( CER_ES9_Aqua-FM3_Edition1-CV)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    The ERBE-like Monthly Regional Averages (ES-9) product contains a month of space and time averaged Clouds and the Earth's Radiant Energy System (CERES) data for a single scanner instrument. The ES-9 is also produced for combinations of scanner instruments. All instantaneous shortwave and longwave fluxes at the Top-of-the-Atmosphere (TOA) from the CERES ES-8 product for a month are sorted by 2.5-degree spatial regions, by day number, and by the local hour of observation. The mean of the instantaneous fluxes for a given region-day-hour bin is determined and recorded on the ES-9 along with other flux statistics and scene information. For each region, the daily average flux is estimated from an algorithm that uses the available hourly data, scene identification data, and diurnal models. This algorithm is 'like' the algorithm used for the Earth Radiation Budget Experiment (ERBE). The ES-9 also contains hourly average fluxes for the month and an overall monthly average for each region. These average fluxes are given for both clear-sky and total-sky scenes. The following CERES ES9 data sets are currently available: CER_ES9_FM1+FM2_Edition1 CER_ES9_PFM+FM1+FM2_Edition1 CER_ES9_PFM+FM1+FM2_Edition2 CER_ES9_PFM+FM1_Edition1 CER_ES9_PFM+FM2_Edition1 CER_ES9_PFM+FM1_Edition2 CER_ES9_PFM+FM2_Edition2 CER_ES9_TRMM-PFM_Edition1 CER_ES9_TRMM-PFM_Edition2 CER_ES9_Terra-FM1_Edition1 CER_ES9_Terra-FM2_Edition1 CER_ES9_FM1+FM2_Edition2 CER_ES9_Terra-FM1_Edition2 CER_ES9_Terra-FM2_Edition2 CER_ES9_Aqua-FM3_Edition1 CER_ES9_Aqua-FM4_Edition1 CER_ES9_FM1+FM2+FM3+FM4_Edition1 CER_ES9_Aqua-FM3_Edition2 CER_ES9_Aqua-FM4_Edition2 CER_ES9_FM1+FM3_Edition2 CER_ES9_FM1+FM4_Edition2 CER_ES9_Aqua-FM3_Edition1-CV CER_ES9_Aqua-FM4_Edition1-CV CER_ES9_Terra-FM1_Edition1-CV CER_ES9_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1998-01-01; Stop_Date=2006-10-31] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost

  5. Khatyrka, a new CV3 find from the Koryak Mountains, Eastern Russia

    Science.gov (United States)

    MacPherson, Glenn J.; Andronicos, Christopher L.; Bindi, Luca; Distler, Vadim V.; Eddy, Michael P.; Eiler, John M.; Guan, Yunbin; Hollister, Lincoln S.; Kostin, Alexander; Kryachko, Valery; Steinhardt, William M.; Yudovskaya, Marina; Steinhardt, Paul J.

    2013-08-01

    A new meteorite find, named Khatyrka, was recovered from eastern Siberia as a result of a search for naturally occurring quasicrystals. The meteorite occurs as clastic grains within postglacial clay-rich layers along the banks of a small stream in the Koryak Mountains, Chukotka Autonomous Okrug of far eastern Russia. Some of the grains are clearly chondritic and contain Type IA porphyritic olivine chondrules enclosed in matrices that have the characteristic platy olivine texture, matrix olivine composition, and mineralogy (olivine, pentlandite, nickel-rich iron-nickel metal, nepheline, and calcic pyroxene [diopside-hedenbergite solid solution]) of oxidized-subgroup CV3 chondrites. A few grains are fine-grained spinel-rich calcium-aluminum-rich inclusions with mineral oxygen isotopic compositions again typical of such objects in CV3 chondrites. The chondritic and CAI grains contain small fragments of metallic copper-aluminum-iron alloys that include the quasicrystalline phase icosahedrite. One grain is an achondritic intergrowth of Cu-Al metal alloys and forsteritic olivine ± diopsidic pyroxene, both of which have meteoritic (CV3-like) oxygen isotopic compositions. Finally, some grains consist almost entirely of metallic alloys of aluminum + copper ± iron. The Cu-Al-Fe metal alloys and the alloy-bearing achondrite clast are interpreted to be an accretionary component of what otherwise is a fairly normal CV3 (oxidized) chondrite. This association of CV3 chondritic grains with metallic copper-aluminum alloys makes Khatyrka a unique meteorite, perhaps best described as a complex CV3 (ox) breccia.

  6. The Gaia Catalogue Second Data Release and Its Implications to Optical Observations of Man-Made Earth Orbiting Objects

    Science.gov (United States)

    Frith, James M.; Buckalew, Brent A.; Cowardin, Heather M.; Lederer, Susan M.

    2018-01-01

    The Gaia catalogue second data release and its implications to optical observations of man-made Earth orbiting objects. Abstract and not the Final Paper is attached. The Gaia spacecraft was launched in December 2013 by the European Space Agency to produce a three-dimensional, dynamic map of objects within the Milky Way. Gaia's first year of data was released in September 2016. Common sources from the first data release have been combined with the Tycho-2 catalogue to provide a 5 parameter astrometric solution for approximately 2 million stars. The second Gaia data release is scheduled to come out in April 2018 and is expected to provide astrometry and photometry for more than 1 billion stars, a subset of which with a the full 6 parameter astrometric solution (adding radial velocity) and positional accuracy better than 0.002 arcsec (2 mas). In addition to precise astrometry, a unique opportunity exists with the Gaia catalogue in its production of accurate, broadband photometry using the Gaia G filter. In the past, clear filters have been used by various groups to maximize likelihood of detection of dim man-made objects but these data were very difficult to calibrate. With the second release of the Gaia catalogue, a ground based system utilizing the G band filter will have access to 1.5 billion all-sky calibration sources down to an accuracy of 0.02 magnitudes or better. In this talk, we will discuss the advantages and practicalities of implementing the Gaia filters and catalogue into data pipelines designed for optical observations of man-made objects.

  7. Central Asia earthquake catalogue from ancient time to 2009

    Directory of Open Access Journals (Sweden)

    Natalya N. Mikhailova

    2015-04-01

    Full Text Available In this work, we present the seismic catalogue compiled for Central Asia (Kazakhstan, Kyrgyzstan, Tajikistan, Uzbekistan and Turkmenistan in the framework of the Earthquake Model Central Asia (EMCA project. The catalogue from 2000 B.C. to 2009 A.D. is composed by 33,034 earthquakes in the MLH magnitude (magnitude by surface waves on horizontal components widely used in practice of the former USSR countries range from 1.5 to 8.3. The catalogue includes both macroseimic and instrumental constrained data, with about 32,793 earthquake after 1900 A.D. The main sources and procedure used to compile the catalogues are discussed, and the comparison with the ISC-GEM catalogue presented. Magnitude of completeness analysis shows that the catalogue is complete down to magnitude 4 from 1959 and to magnitude 7 from 1873, whereas the obtained regional b value is 0.805.

  8. Catalogue 2.0 the future of the library catalogue

    CERN Document Server

    Chambers, Sally

    2014-01-01

    Brings together some of the foremost international cataloguing practitioners and thought leaders, including Lorcan Dempsey, Emmanuelle Bermès, Marshall Breeding and Karen Calhoun, to provide an overview of the current state of the art of the library catalogue and look ahead to see what the library catalogue might become.

  9. BKE: The catalogue of Bunker-Est Vesuvian station

    International Nuclear Information System (INIS)

    Sarao, A.; Peresan, A.; Vaccari, F.; De Natale, G.; Mariano, A.

    2002-06-01

    A catalogue of 9003 earthquakes associated to the Vesuvian volcano activity as recorded at Bunker Est station (BKE), located on Mt. Vesuvius and operated by the Osservatorio Vesuviano (OV), is presented here. The aim of this catalogue is to integrate the information collected in the catalogue compiled by OV that contains the volcanic earthquakes recorded at station OVO (OVO catalogue) since February 1972. A brief statistical description of the data included in the catalogue BKE and of the empirical relations used for the estimate of the magnitude MBKE from the duration is provided, together with the essential information about the catalogue source. A complete list of the events reported in the catalogue BKE and a description of its format is given in the Appendix. The catalogue BKE has been realized with the cooperation of the University of Trieste - Department of Earth Sciences, the International Centre for Theoretical Physics (ICTP) - Structure and Non-linear Dynamics of the earth (SAND) Group, and the Osservatorio Vesuviano of Naples in the framework of the project 'Eruptive Scenarios from Physical Modeling and Experimental Volcanology' funded by INGV. (author)

  10. Organisation des travaux ST-CV

    CERN Document Server

    Martel, C; CERN. Geneva. ST Division

    2003-01-01

    Débutée il y a deux ans, la phase de construction des installations de refroidissement du LHC a atteint en 2003 son apogée. De nombreux autres projets sont également gérés par le groupe dans divers secteurs du laboratoire. La spécificité du groupe est de réaliser des installations complexes impliquant des spécificités diverses telles qu’aéraulique, hydraulique, électrique, etc. Pour faire face à ces demandes la section travaux du groupe ST CV a adopté une structure capable de réaliser ces divers projets avec un minimum de personnel. La première partie de ce document décrit l’organisation de la section travaux ST CV. Dans une deuxième partie, les auteurs dressent un état des lieux des chantiers par projet en décrivant plus particulièrement les activités dans les domaines du traitement d’air et de refroidissement par eau.

  11. Mineralogy and Petrography of MIL 090001, a Highly Altered CV Chondrite from the Reduced Sub-Group

    Science.gov (United States)

    Keller, Lindsay P.

    2011-01-01

    MIL 090001 is a large (greater than 6 kg) CV chondrite from the reduced subgroup (CV(sub red)) that was recovered during the 2009-2010 ANSMET field season [1]. The CV(sub red) subgroup meteorites retain primitive characteristics and have escaped the Na and Fe meta-somatism that affected the oxidized (CV(sub ox)) subgroups. MIL 090001 is, however, reported to be altered [1], and thus a major objective of this study is to characterize its mineralogy and petrography and the extent of the alteration.

  12. CERES ERBE-like Instantaneous TOA Estimates (ES-8) in HDF (CER_ES8_Terra-FM1_Edition1-CV)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    The ES-8 archival data product contains a 24-hour, single-satellite, instantaneous view of scanner fluxes at the top-of-atmosphere (TOA) reduced from spacecraft altitude unfiltered radiances using Earth Radiation Budget Experiment (ERBE) scanner Inversion algorithms and the ERBE shortwave (SW) and longwave (LW) Angular Distribution Models (ADMs). The ES-8 also includes the total (TOT), SW, LW, and window (WN) channel radiometric data; SW, LW, and WN unfiltered radiance values; and the ERBE scene identification for each measurement. These data are organized according to the CERES 3.3-second scan into 6.6-second records. As long as there is one valid scanner measurement within a record, the ES-8 record will be generated. The following CERES ES8 data sets are currently available: CER_ES8_TRMM-PFM_Edition1 CER_ES8_TRMM-PFM_Edition2 CER_ES8_TRMM-PFM_Transient-Ops2 CER_ES8_Terra-FM1_Edition1 CER_ES8_Terra-FM2_Edition1 CER_ES8_Terra-FM1_Edition2 CER_ES8_Terra-FM2_Edition2 CER_ES8_Aqua-FM3_Edition1 CER_ES8_Aqua-FM4_Edition1 CER_ES8_Aqua-FM3_Edition2 CER_ES8_Aqua-FM4_Edition2 CER_ES8_Aqua-FM3_Edition1-CV CER_ES8_Aqua-FM4_Edition1-CV CER_ES8_Terra-FM1_Edition1-CV CER_ES8_Terra-FM1_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2006-09-30] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

  13. Construction of a subgenomic CV-B3 replicon expressing emerald green fluorescent protein to assess viral replication of a cardiotropic enterovirus strain in cultured human cells.

    Science.gov (United States)

    Wehbe, Michel; Huguenin, Antoine; Leveque, Nicolas; Semler, Bert L; Hamze, Monzer; Andreoletti, Laurent; Bouin, Alexis

    2016-04-01

    Coxsackieviruses B (CV-B) (Picornaviridae) are a common infectious cause of acute myocarditis in children and young adults, a disease, which is a precursor to 10-20% of chronic myocarditis and dilated cardiomyopathy (DCM) cases. The mechanisms involved in the disease progression from acute to chronic myocarditis phase and toward the DCM clinical stage are not fully understood but are influenced by both viral and host factors. Subgenomic replicons of CV-B can be used to assess viral replication mechanisms in human cardiac cells and evaluate the effects of potential antiviral drugs on viral replication activities. Our objectives were to generate a reporter replicon from a cardiotropic prototype CV-B3/28 strain and to characterize its replication properties into human cardiac primary cells. To obtain this replicon, a cDNA plasmid containing the full CV-B3/28 genome flanked by a hammerhead ribozyme sequence and an MluI restriction site was generated and used as a platform for the insertion of sequences encoding emerald green fluorescent protein (EmGFP) in place of those encoding VP3. In vitro transcribed RNA from this plasmid was transfected into HeLa cells and human primary cardiac cells and was able to produce EmGFP and VP1-containing polypeptides. Moreover, non-structural protein biological activity was assessed by the specific cleavage of eIF4G1 by viral 2A(pro). Viral RNA replication was indirectly demonstrated by inhibition assays, fluoxetine was added to cell culture and prevented the EmGFP synthesis. Our results indicated that the EmGFP CV-B3 replicon was able to replicate and translate as well as the CV-B3/28 prototype strain. Our EmGFP CV-B3 replicon will be a valuable tool to readily investigate CV-B3 replication activities in human target cell models. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. eGenomics: Cataloguing Our Complete Genome Collection III

    Directory of Open Access Journals (Sweden)

    Dawn Field

    2007-01-01

    Full Text Available This meeting report summarizes the proceedings of the “eGenomics: Cataloguing our Complete Genome Collection III” workshop held September 11–13, 2006, at the National Institute for Environmental eScience (NIEeS, Cambridge, United Kingdom. This 3rd workshop of the Genomic Standards Consortium was divided into two parts. The first half of the three-day workshop was dedicated to reviewing the genomic diversity of our current and future genome and metagenome collection, and exploring linkages to a series of existing projects through formal presentations. The second half was dedicated to strategic discussions. Outcomes of the workshop include a revised “Minimum Information about a Genome Sequence” (MIGS specification (v1.1, consensus on a variety of features to be added to the Genome Catalogue (GCat, agreement by several researchers to adopt MIGS for imminent genome publications, and an agreement by the EBI and NCBI to input their genome collections into GCat for the purpose of quantifying the amount of optional data already available (e.g., for geographic location coordinates and working towards a single, global list of all public genomes and metagenomes.

  15. Immunogenicity and safety of the 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) co-administered with DTPa vaccine in Japanese children: A randomized, controlled study.

    Science.gov (United States)

    Iwata, Satoshi; Kawamura, Naohisa; Kuroki, Haruo; Tokoeda, Yasunobu; Miyazu, Mitsunobu; Iwai, Asayuki; Oishi, Tomohiro; Sato, Tomohide; Suyama, Akari; François, Nancy; Shafi, Fakrudeen; Ruiz-Guiñazú, Javier; Borys, Dorota

    2015-01-01

    This phase III, randomized, open-label, multicenter study (NCT01027845) conducted in Japan assessed the immunogenicity, safety, and reactogenicity of 10-valent pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV, given intramuscularly) co-administered with diphtheria-tetanus-acellular pertussis vaccine (DTPa, given subcutaneously). Infants (N=360 ) were randomized (2:1) to receive either PHiD-CV and DTPa (PHiD-CV group) or DTPa alone (control group) as 3-dose primary vaccination (3-4-5 months of age) and booster vaccination (17-19 months of age). Immune responses were measured before and one month after primary/booster vaccination and adverse events (AEs) were recorded. Post-primary immune responses were non-inferior to those in pivotal/efficacy European or Latin American pneumococcal protein D-conjugate vaccine studies. For each PHiD-CV serotype, at least 92.6% of infants post-primary vaccination and at least 97.7% of children post-booster had pneumococcal antibody concentrations ≥0.2 μg/ml, and at least 95.4% post-primary and at least 98.1% post-booster had opsonophagocytic activity (OPA) titers ≥8 . Geometric mean antibody concentrations and OPA titers (except OPA titer for 6B) were higher post-booster than post-priming for each serotype. All PHiD-CV-vaccinated children had anti-protein D antibody concentrations ≥100 EL.U/ml one month post-primary/booster vaccination and all were seroprotected/seropositive against each DTPa antigen. Redness and irritability were the most common solicited AEs in both groups. Incidences of unsolicited AEs were comparable between groups. Serious AEs were reported for 47 children (28 in PHiD-CV group); none were assessed as vaccine-related. In conclusion, PHiD-CV induced robust immune responses and was well tolerated when co-administered with DTPa in a 3-dose priming plus booster regimen to Japanese children.

  16. Avaliação das subclasses IgG1 e IgG3 na doença hemolítica perinatal Assessment of IgG1 and IgG3 subclasses in perinatal hemolytic disease

    Directory of Open Access Journals (Sweden)

    Maria A. Araújo

    2003-01-01

    Full Text Available A doença hemolítica perinatal (DHPN ainda é um problema clínico. Nenhum teste isolado prediz, com segurança, a gravidade do quadro hemolítico. O objetivo do presente estudo foi determinar as subclasses de anticorpos IgG1 e IgG3 por citometria de fluxo no soro de 42 gestantes isoimunizadas e correlacionar os dados obtidos com a gravidade da DHPN. A distribuição dos fetos ou neonatos segundo a gravidade do quadro hemolítico evidenciou 13 casos com doença leve, 16 casos com doença moderada e 13 com doença grave. As subclasses foram detectadas em 33/42 (79% amostras. A subclasse IgG1, isoladamente, foi evidenciada em 14/33 (42,4% casos. Na relação entre gravidade da doença e subclasses de IgG, observou-se que IgG1 isolada foi encontrada em todos os grupos, e os valores da mediana de intensidade de fluorescência (MIF foram significativamente mais altos nas formas mais graves da DHPN (pThe hemolytic disease of the newborn (HDN continues to be a clinical problem in spite of prophylaxis. To date, none of the available tests, developed to predict the severity of HDN, has provided complete reliability. The objective of the present study was to determine the IgG1 and IgG3 subclasses in 42 isoimmunized pregnant women, and to correlate them with clinical severity of hemolytic disease. The IgG subclasses were determined employing flow cytometry. According to the clinical severity of HDN, fetuses and newborn babies were classified as 13 mild, 16 moderate and 13 severe cases. The IgG subclasses were detected in 33 of the 42 pregnant women. Of these, IgG1 was predominant in 72.7% of the cases; either isolated (42.4% or in association with IgG3 (30.3%. IgG1 was present in all the three clinical severity categories, however, its values were significantly higher in cases with greater clinical severity of HDN (p<0.01. On the other hand, the distribution of IgG3 values within each group was not statistically significant (p=0.11. IgG3 seems to be more

  17. Mind the Gap when Data Mining the Ritter-Kolb Cataclysmic Variable Catalogue

    Science.gov (United States)

    Sparks, Warren M.; Sion, Edward M.

    2017-01-01

    The cataclysmic variable (CV) binary consists of a white dwarf primary and a low-mass secondary which overflows its Roche lobe. The Ritter-Kolb catalogue (2003, A&A, 404, 301) is a collection (~1000) of CV binaries and related objects. We have mined this catalogue for CVs with unevolved secondaries whose mass ratio (secondary/primary) is known (~130). A plot of the secondary mass verses the log of the orbital period exhibits the well-known period gap at 2-3 hrs. In addition, this plot shows that the secondary masses just above the period gap are collectively much larger than those just below. The average of the first ten secondary masses above the period is 180% larger than the average below the gap.The disrupted magnetic braking hypothesis (Howell, Nelson, and Rappaport 2001, ApJ, 550, 897 [HNR]) predicts that when the secondary becomes fully convective, the magnetic braking, which has driven the secondary out of thermal equilibrium, stops. In adjusting to thermal equilibrium the secondary shrinks below its Roche lobe and no longer loses mass. The binary system ceases to appear as a CV until gravitational radiation loss brings the secondary back in contact with its Roche lobe. This scenario is at odds with the apparent secondary mass loss across the period gap. Either the secondary continues to lose mass while crossing the period gap or the secondary masses are miscalculated!Magnetic braking causes the secondary to expand or inflate larger than its single star counterpart. Any orbital parameter calculation which assumes a radius-mass relationship based on single main-sequence stars will overestimate the mass of the secondary. We can approximate this mass overestimation from calculations by HNR which take into account the thermal heating from magnetic braking. Using this approximation as a first-order correction to the secondary mass, we replot the deflated secondary mass versus the binary period. The deflated masses immediately above and below the period gap are

  18. Catalogue of meteorites from South America

    CERN Document Server

    Acevedo, Rogelio Daniel; García, Víctor Manuel

    2014-01-01

    The first Catalogue of Meteorites from South America includes new specimens never previously reported, while doubtful cases and pseudometeorites have been deliberately omitted.The falling of these objects is a random event, but the sites where old meteorites are found tend to be focused in certain areas, e.g. in the deflation surfaces in Chile's Atacama Desert, due to favorable climate conditions and ablation processes.Our Catalogue provides basic information on each specimen like its provenance and the place where it was discovered (in geographic co-ordinates and with illustrative maps), its

  19. The Euro-Mediterranean Tsunami Catalogue

    Directory of Open Access Journals (Sweden)

    Alessandra Maramai

    2014-08-01

    Full Text Available A unified catalogue containing 290 tsunamis generated in the European and Mediterranean seas since 6150 B.C. to current days is presented. It is the result of a systematic and detailed review of all the regional catalogues available in literature covering the study area, each of them having their own format and level of accuracy. The realization of a single catalogue covering a so wide area and involving several countries was a complex task that posed a series of challenges, being the standardization and the quality of the data the most demanding. A “reliability” value was used to rate equally the quality of the data for each event and this parameter was assigned based on the trustworthiness of the information related to the generating cause, the tsunami description accuracy and also on the availability of coeval bibliographical sources. Following these criteria we included in the catalogue events whose reliability ranges from 0 (“very improbable tsunami” to 4 (“definite tsunami”. About 900 documentary sources, including historical documents, books, scientific reports, newspapers and previous catalogues, support the tsunami data and descriptions gathered in this catalogue. As a result, in the present paper a list of the 290 tsunamis with their main parameters is reported. The online version of the catalogue, available at http://roma2.rm.ingv.it/en/facilities/data_bases/52/catalogue_of_the_euro-mediterranean_tsunamis, provides additional information such as detailed descriptions, pictures, etc. and the complete list of bibliographical sources. Most of the included events have a high reliability value (3= “probable” and 4= “definite” which makes the Euro-Mediterranean Tsunami Catalogue an essential tool for the implementation of tsunami hazard and risk assessment.

  20. Slurry sampling in serum blood for mercury determination by CV-AFS

    International Nuclear Information System (INIS)

    Aranda, Pedro R.; Gil, Raul A.; Moyano, Susana; De Vito, Irma; Martinez, Luis D.

    2009-01-01

    The heavy metal mercury (Hg) is a neurotoxin known to have a serious health impact even at relatively low concentrations. A slurry method was developed for the sensitive and precise determination of mercury in human serum blood samples by cold vapor generation coupled to atomic fluorescence spectrometry (CV-AFS). All variables related to the slurry formation were studied. The optimal hydrochloric concentration and tin(II) chloride concentration for CV generation were evaluated. Calibration within the range 0.1-10 μg L -1 Hg was performed with the standard addition method, and compared with an external calibration. Additionally, the reliability of the results obtained was evaluated by analyzing mercury in the same samples, but submitted to microwave-assisted digestion method. The limit of detection was calculated as 25 ng L -1 and the relative standard deviation was 3.9% at levels around of 0.4 μg L -1 Hg

  1. Irradiated graphite studies prior to decommissioning of G1, G2 and G3 reactors

    International Nuclear Information System (INIS)

    Bonal, J.P.; Vistoli, J.Ph.; Combes, C.

    2005-01-01

    G1 (46 MW th ), G2 (250 MW th ) and G3 (250 MW th ) are the first French plutonium production reactors owned by CEA (Commissariat a l'Energie Atomique). They started to be operated in 1956 (G1), 1959 (G2) and 1960 (G3); their final shutdown occurred in 1968, 1980 and 1984 respectively. Each reactor used about 1200 tons of graphite as moderator, moreover in G2 and G3, a 95 tons graphite wall is used to shield the rear side concrete from neutron irradiation. G1 is an air cooled reactor operated at a graphite temperature ranging from 30 C to 230 C; G2 and G3 are CO 2 cooled reactors and during operation the graphite temperature is higher (140 C to 400 C). These reactors are now partly decommissioned, but the graphite stacks are still inside the reactors. The graphite core radioactivity has decreased enough so that a full decommissioning stage may be considered. Conceming this decommissioning, the studies reported here are: (i) stored energy in graphite, (ii) graphite radioactivity measurements, (iii) leaching of radionuclide ( 14 C, 36 Cl, 63 Ni, 60 Co, 3 H) from graphite, (iv) chlorine diffusion through graphite. (authors)

  2. Effects of {gamma}-ray irradiation on the C-V and G/{omega}-V characteristics of Al/SiO{sub 2}/p-Si (MIS) structures

    Energy Technology Data Exchange (ETDEWEB)

    Doekme, Ilbilge [Science Education Department, Faculty of Education, Ahi Evran University, Kirsehir (Turkey)], E-mail: ilbilgedokme@gazi.edu.tr; Durmus, Perihan; Altindal, Semsettin [Physics Department, Faculty of Arts and Sciences, Gazi University, 06500 Teknikokullar, Ankara (Turkey)

    2008-03-15

    The effect of the {sup 60}C{sub o} ({gamma}-ray) exposure on the electrical characteristics of Al/SiO{sub 2}/p-Si (MIS) structures has been investigated using capacitance-voltage (C-V) and conductance-voltage (G/{omega}-V) measurements. The MIS structures were stressed with a bias of 0 V during {sup 60}C{sub o}{gamma}-sources irradiation with the total dose range from 0 to 25 kGy. The C-V and G/{omega}-V characteristics were measured at 500 kHz and room temperature before and after {sup 60}C{sub o}{gamma}-ray irradiation. The results indicated that {gamma}-irradiation caused an increase in the barrier height {phi}{sub B}, interface states N{sub ss} and depletion layer width W{sub D} obtained from reverse bias C-V measurements. The series resistance R{sub s} profile for various radiation doses was obtained from forward and reverse bias C-V and G/{omega}-V measurements. Both C-V and G/{omega}-V characteristics indicate that the total dose radiation hardness of MIS structures may be limited by the decisive properties of the SiO{sub 2}/Si interface to radiation-induced damage. After {gamma}-irradiation, the decrease in capacitance of MIS structure results in the increase in the semiconductor depletion width.

  3. Impact of magnitude uncertainties on seismic catalogue properties

    Science.gov (United States)

    Leptokaropoulos, K. M.; Adamaki, A. K.; Roberts, R. G.; Gkarlaouni, C. G.; Paradisopoulou, P. M.

    2018-05-01

    Catalogue-based studies are of central importance in seismological research, to investigate the temporal, spatial and size distribution of earthquakes in specified study areas. Methods for estimating the fundamental catalogue parameters like the Gutenberg-Richter (G-R) b-value and the completeness magnitude (Mc) are well established and routinely applied. However, the magnitudes reported in seismicity catalogues contain measurement uncertainties which may significantly distort the estimation of the derived parameters. In this study, we use numerical simulations of synthetic data sets to assess the reliability of different methods for determining b-value and Mc, assuming the G-R law validity. After contaminating the synthetic catalogues with Gaussian noise (with selected standard deviations), the analysis is performed for numerous data sets of different sample size (N). The noise introduced to the data generally leads to a systematic overestimation of magnitudes close to and above Mc. This fact causes an increase of the average number of events above Mc, which in turn leads to an apparent decrease of the b-value. This may result to a significant overestimation of seismicity rate even well above the actual completeness level. The b-value can in general be reliably estimated even for relatively small data sets (N < 1000) when only magnitudes higher than the actual completeness level are used. Nevertheless, a correction of the total number of events belonging in each magnitude class (i.e. 0.1 unit) should be considered, to deal with the magnitude uncertainty effect. Because magnitude uncertainties (here with the form of Gaussian noise) are inevitable in all instrumental catalogues, this finding is fundamental for seismicity rate and seismic hazard assessment analyses. Also important is that for some data analyses significant bias cannot necessarily be avoided by choosing a high Mc value for analysis. In such cases, there may be a risk of severe miscalculation of

  4. Halo substructure in the SDSS-Gaia catalogue: streams and clumps

    Science.gov (United States)

    Myeong, G. C.; Evans, N. W.; Belokurov, V.; Amorisco, N. C.; Koposov, S. E.

    2018-04-01

    We use the Sloan Digital Sky Survey (SDSS)-Gaia Catalogue to identify six new pieces of halo substructure. SDSS-Gaia is an astrometric catalogue that exploits SDSS data release 9 to provide first epoch photometry for objects in the Gaia source catalogue. We use a version of the catalogue containing 245 316 stars with all phase-space coordinates within a heliocentric distance of ˜10 kpc. We devise a method to assess the significance of halo substructures based on their clustering in velocity space. The two most substantial structures are multiple wraps of a stream which has undergone considerable phase mixing (S1, with 94 members) and a kinematically cold stream (S2, with 61 members). The member stars of S1 have a median position of (X, Y, Z) = (8.12, -0.22, 2.75) kpc and a median metallicity of [Fe/H] = -1.78. The stars of S2 have median coordinates (X, Y, Z) = (8.66, 0.30, 0.77) kpc and a median metallicity of [Fe/H] = -1.91. They lie in velocity space close to some of the stars in the stream reported by Helmi et al. By modelling, we estimate that both structures had progenitors with virial masses ≈1010M⊙ and infall times ≳ 9 Gyr ago. Using abundance matching, these correspond to stellar masses between 106 and 107M⊙. These are somewhat larger than the masses inferred through the mass-metallicity relation by factors of 5 to 15. Additionally, we identify two further substructures (S3 and S4 with 55 and 40 members) and two clusters or moving group (C1 and C2 with 24 and 12) members. In all six cases, clustering in kinematics is found to correspond to clustering in both configuration space and metallicity, adding credence to the reliability of our detections.

  5. An All-Sky Portable (ASP) Optical Catalogue

    Science.gov (United States)

    Flesch, Eric Wim

    2017-06-01

    This optical catalogue combines the all-sky USNO-B1.0/A1.0 and most-sky APM catalogues, plus overlays of SDSS optical data, into a single all-sky map presented in a sparse binary format that is easily downloaded at 9 Gb zipped. Total count is 1 163 237 190 sources and each has J2000 astrometry, red and blue magnitudes with PSFs and variability indicator, and flags for proper motion, epoch, and source survey and catalogue for each of the photometry and astrometry. The catalogue is available on http://quasars.org/asp.html, and additional data for this paper is available at http://dx.doi.org/10.4225/50/5807fbc12595f.

  6. Scalable global grid catalogue for Run3 and beyond

    Science.gov (United States)

    Martinez Pedreira, M.; Grigoras, C.; ALICE Collaboration

    2017-10-01

    The AliEn (ALICE Environment) file catalogue is a global unique namespace providing mapping between a UNIX-like logical name structure and the corresponding physical files distributed over 80 storage elements worldwide. Powerful search tools and hierarchical metadata information are integral parts of the system and are used by the Grid jobs as well as local users to store and access all files on the Grid storage elements. The catalogue has been in production since 2005 and over the past 11 years has grown to more than 2 billion logical file names. The backend is a set of distributed relational databases, ensuring smooth growth and fast access. Due to the anticipated fast future growth, we are looking for ways to enhance the performance and scalability by simplifying the catalogue schema while keeping the functionality intact. We investigated different backend solutions, such as distributed key value stores, as replacement for the relational database. This contribution covers the architectural changes in the system, together with the technology evaluation, benchmark results and conclusions.

  7. Neisseria meningitidis Group A IgG1 and IgG2 Subclass Immune Response in African Children Aged 12–23 Months Following Meningococcal Vaccination

    Science.gov (United States)

    Holme, Daniel; Findlow, Helen; Sow, Samba O.; Idoko, Olubukola T.; Preziosi, Marie-Pierre; Carlone, George; Plikaytis, Brian D.; Borrow, Ray

    2015-01-01

    Background. A group A meningococcal conjugate vaccine, PsA-TT, was licensed in 2010 and was previously studied in a phase 2 clinical trial to evaluate its safety and immunogenicity in African children 12–23 months of age. Methods. Subjects received either PsA-TT; meningococcal group A, C, W, Y polysaccharide vaccine (PsACWY); or Haemophilus influenzae type b conjugate vaccine (Hib-TT). Forty weeks following primary vaccination, the 3 groups were further randomized to receive either PsA-TT, one-fifth dose of PsACWY, or Hib-TT. Group A–specific immunoglobulin G (IgG) subclass response was characterized using an enzyme-linked immunosorbent assay. Results. The predominant IgG subclass response, regardless of vaccine, was IgG1. One month following primary vaccination, the geometric mean concentrations (GMCs) of IgG1 and IgG2 in the PsA-TT group were 21.73 µg/mL and 6.27 µg/mL, whereas in the PsACWY group the mean GMCs were 2.01 µg/mL and 0.97 µg/mL, respectively (P Group A–specific IgG1 and IgG2 GMCs remained greater in the PsA-TT group than in the PsACWY group 40 weeks following primary vaccination (P vaccines. Conclusions. Vaccination of African children aged 12–24 months with either PsA-TT or PsACWY elicited a predominantly IgG1 response. The IgG1:IgG2 mean ratio decreased following successive vaccination with PsACWY, indicating a shift toward IgG2, suggestive of the T-cell–independent immune response commonly associated with polysaccharide antigens. Clinical Trials Registration. SRCTN78147026. PMID:26553689

  8. ESO Catalogue Facility Design and Performance

    Science.gov (United States)

    Moins, C.; Retzlaff, J.; Arnaboldi, M.; Zampieri, S.; Delmotte, N.; Forchí, V.; Klein Gebbinck, M.; Lockhart, J.; Micol, A.; Vera Sequeiros, I.; Bierwirth, T.; Peron, M.; Romaniello, M.; Suchar, D.

    2013-10-01

    The ESO Phase 3 Catalogue Facility provides investigators with the possibility to ingest catalogues resulting from ESO public surveys and large programs and to query and download their content according to positional and non-positional criteria. It relies on a chain of tools that covers the complete workflow from submission to validation and ingestion into the ESO archive and catalogue repository and a web application to browse and query catalogues. This repository consists of two components. One is a Sybase ASE relational database where catalogue meta-data are stored. The second one is a Sybase IQ data warehouse where the content of each catalogue is ingested in a specific table that returns all records matching a user's query. Spatial indexing has been implemented in Sybase IQ to speed up positional queries and relies on the Spherical Geometry Toolkit from the Johns Hopkins University which implements the Hierarchical Triangular Mesh (HTM) algorithm. It is based on a recursive decomposition of the celestial sphere in spherical triangles and the assignment of an index to each of them. It has been complemented with the use of optimized indexes on the non-positional columns that are likely to be frequently used as query constraints. First tests performed on catalogues such as 2MASS have confirmed that this approach provides a very good level of performance and a smooth user experience that are likely to facilitate the scientific exploitation of catalogues.

  9. LU60645GT and MA132843GT Catalogues of Lunar and Martian Impact Craters Developed Using a Crater Shape-based Interpolation Crater Detection Algorithm for Topography Data

    Science.gov (United States)

    Salamuniccar, Goran; Loncaric, Sven; Mazarico, Erwan Matias

    2012-01-01

    For Mars, 57,633 craters from the manually assembled catalogues and 72,668 additional craters identified using several crater detection algorithms (CDAs) have been merged into the MA130301GT catalogue. By contrast, for the Moon the most complete previous catalogue contains only 14,923 craters. Two recent missions provided higher-quality digital elevation maps (DEMs): SELENE (in 1/16° resolution) and Lunar Reconnaissance Orbiter (we used up to 1/512°). This was the main motivation for work on the new Crater Shape-based interpolation module, which improves previous CDA as follows: (1) it decreases the number of false-detections for the required number of true detections; (2) it improves detection capabilities for very small craters; and (3) it provides more accurate automated measurements of craters' properties. The results are: (1) LU60645GT, which is currently the most complete (up to D>=8 km) catalogue of Lunar craters; and (2) MA132843GT catalogue of Martian craters complete up to D>=2 km, which is the extension of the previous MA130301GT catalogue. As previously achieved for Mars, LU60645GT provides all properties that were provided by the previous Lunar catalogues, plus: (1) correlation between morphological descriptors from used catalogues; (2) correlation between manually assigned attributes and automated measurements; (3) average errors and their standard deviations for manually and automatically assigned attributes such as position coordinates, diameter, depth/diameter ratio, etc; and (4) a review of positional accuracy of used datasets. Additionally, surface dating could potentially be improved with the exhaustiveness of this new catalogue. The accompanying results are: (1) the possibility of comparing a large number of Lunar and Martian craters, of e.g. depth/diameter ratio and 2D profiles; (2) utilisation of a method for re-projection of datasets and catalogues, which is very useful for craters that are very close to poles; and (3) the extension of the

  10. Framework and catalogue of tools for Participatory monitoring for Farmer Family Learning Groups and Marketing Associations

    DEFF Research Database (Denmark)

    Vaarst, Mette; Nalunga, Jane; Tibasiima, Thaddeo

    2016-01-01

    This catalogue of ideas has been developed in a joint effort by six organisations (Caritas Kampala, Uganda Rural Development (URDT), Sulma Foods, Africa2000Network (A2N), National Organic Agricultural Movement of Uganda (NOGAMU), and Organic Denmark) in the project ECOSAF in Uganda. The focus...... of this project (2013-2015) was Farmer Family Learning Groups (FFLG) as a method for developing long-term food security through social capital building. Furthermore, another project based on the FFLG approach but focusing on the formation of Marketing Associations (MAs) contributed to this booklet. This project...... was carried through in a joined effort between Sustainable Agricultural Trainers Network (SATNET), NOGAMU and OD. SATNET is an umbrella organization with 40 member organisations, and in the project, a number of MAs linked up to the organization as well. This catalogue is a result of inputs from more than 40...

  11. Irpinia 1980, Southern Latium and Abruzzi National Park 1984, Zafferana Etnea (Sicily) 1984, Mexico City 1985 earthquakes: Catalogues of damage

    International Nuclear Information System (INIS)

    Sofo, G.

    1987-01-01

    The iconographic and descriptive documentation is collected in catalogues which are compiled in the most objective form in order to permit: (1) the determination of the behaviour of typologies and structural details; (2) the assessment of their relations with the aspects of buildings as a whole; (3) the comparison with analogue or sharply different typologies. The aim of catalogues is to establish an irreplaceble experimental basis for studies devoted to: - verify deficiencies or properties of design and building techniques; - verify possible insufficiency of antiseismic regulations; - establish univoque correlations between structural effects and macroseismic intensity. Catalogues give also reliable information for building seismic instrumentation programs, e.g. the one that ENEA is developing in cooperation with the Ministry of Works. Catalogues have been framed into a necessary compromise between representative completeness and the exigencies of survey over a sufficiently large number of buildings. (orig./HP)

  12. Determination of spatial parameters for different star groups in the Hertzsprung-Russell diagram

    International Nuclear Information System (INIS)

    Kharadze, E.K.; Bartaya, R.A.; Vereshchagin, S.V.; Dluzhnevskaya, O.B.; Pavlovskaya, E.D.; Piskunov, A.Eh.; AN SSSR, Moscow. Astronomicheskij Sovet; Moskovskij Gosudarstvennyj Univ.

    1987-01-01

    Space densities and parameters of z-distribution for ten star groups in the Hertzsprung - Russell diagram (A - K3, A - G4, A - G5) were determined. Data from the Abastumani two-dimensional spectral classification catalogue, and a statistical procedure of data processing, allowing to take into account uncertainties of observational data as well as the catalogue selection effect, were used. The study of the space distributions allowed to carry out an independent estimation of a luminosity dispersion for different sequences in the Hertsprung - Russell diagram

  13. Energy research projects in the Nordic countries - catalogue 1983

    International Nuclear Information System (INIS)

    1983-01-01

    The Nordic energy ministers at their meeting February 9, 1982 agreed upon a working plan for the Nordic energy cooperation. As part of this plan a contact group was established in order to maintain coordination and cooperation within the area of energy research and development. This group decided April 1982 to establish a catalogue of energy research projects in the Nordic countries. A pilot catalogue was published in June 1982. The 1983 catalogue gives an up-to-date survey of energy research and development projects in the Nordic countries. About 2125 projects are described, and information is given on investigator(s), performing organization, financing body, funds, and period. The catalogue is prepared by the Nordic energy libraries through their cooperation in Nordic Atomic Libraries Joint Secretariat. The information is also included in the data base Nordic Energy Index (NEI), which is online accessible at I/S Datacentralen, Copenhagen, via EURONET, SCANNET, TYMNET, AND TELENET. (BP)

  14. Design and development of correlation techniques to maintain a space surveillance system catalogue

    Science.gov (United States)

    Olmedo, E.; Sánchez Ortiz, Noelia; Lerate, Mercedes; Belló-Mora, Miguel; Klinkrad, H.

    2009-10-01

    A growing interest exists in a future, autonomous European Space Surveillance System (ESSS). Currently, most of the knowledge about Earth-orbiting space objects is based on information provided by the USASPACECOM. This paper presents the required initial orbit determination (IOD) and correlation techniques to process optical measurements. Former studies were focused on the handling of radar measurements, which are summarised with the aim of describing a global procedure for processing hybrid measurement types (combination of radar and optic data for catalogue maintenance). The introduction of manoeuvres are presented due to their importance in the space object catalogue maintenance. The detection of uncatalogued objects and the successful correlation of already catalogued objects involve two different tasks for telescopes: survey and tasking. Assumptions for both strategies are developed on the basis of the previous work developed at the University of Berne (see [T. Flohrer, T. Schildknecht, R. Musci, E. Stöveken, Performance estimation for GEO space surveillance, Advances in Space Research 35 (2005). [1]; T. Flohrer, T. Schildknecht, R. Musci, Proposed strategies for optical observations in a future European Space Surveillance Network, presented in the 36th COSPAR Scientific Assembly (2006). [2]; R. Musci, T. Schildknecht, M. Ploner, Orbit improvement for GEO objects using follow-up observations, Advances in Space Research 34 (2004). [3]; R. Musci, T. Schildknecht, M. Ploner, G. Beutler, Orbit improvement for GTO objects using follow-up observations, Advances in Space Research 35 (2005). [4]; R. Musci, T. Schildknecht, T. Flohrer, G. Beutler, Concept for a catalogue of space debris in GEO, Proceedings of the Fourth European Conference on Space Debris, (ESA SP-587, 2005). [5

  15. VizieR Online Data Catalog: Catalogue of Radio Stars (Wendker, 2001)

    Science.gov (United States)

    Wendker, H. J.

    2015-06-01

    The first version of this catalogue was published in Abh.Hamburger Sternw. 1978, Vol.10, p 1ff. (CDS Catalogue II/129). A second version was published in 1987 (1987A&AS...69...87W) and microfiches (CDS Catalogue II/147). A third version was published 1995A&AS..109..177W (CDS Catalogue II/199). The basic concept of the earlier versions is preserved (in file "catalog.txt"), namely one entry per star per frequency per paper. Space is now provided, however, to add more informations. These may be of technical or astronomical nature. Usually month and year of observation and the number of independent data points or length of monitoring session are given. In the file "catalog.txt", all radio data are preceded by a header which contains information on the star or stellar system. (Note, that a physical stellar system is regarded as one single entry and that comments pertaining to individual components are found directly behind the observational data). Stellar data like names, position, proper motion, magnitudes and spectroscopic types are given in fixed format in a self-explanatory fashion. It is tried to have typical values from commonly available references. It is not intended to compete here with other compilations. These header informations are collected when the star is entered for the first time. They are only changed when new values are available while additional radio references are added. An arbitrarily expandable section for unformatted text finishes the header. Finally, the units of the radio data remain in MHz (column#1) and mJy (columns #2. and #3). All coordinates refer to epoch and equinox 1950.0 (e.g. B1950). This is a so-called merged version e.g. all stars, those detected at least once and those with upper limits only, are listed in order of ascending right ascension. The detected stars are marked with a "D" in the outermost right hand column in lines 1 to 5 ('D' in column "Det" of the file "stars.dat"). The last updating occurred on 2001-Mar-06. In this

  16. UCI2001: The updated catalogue of Italy

    International Nuclear Information System (INIS)

    Peresan, A.; Panza, G.F.

    2002-05-01

    A new updated earthquake catalogue for the Italian territory, named UCI2001, is described here; it consists of an updated and revised version of the CCI1996 catalogue (Peresan et al., 1997). The revision essentially corresponds to the incorporation of data from the NEIC (National Earthquake Information Centre) and ALPOR (Catalogo delle Alpi Orientali) catalogues, while the updating is performed using the NEIC Preliminary Determinations of Epicenters since 1986. A brief overview of the catalogues used for the monitoring of seismicity in the Italian area is provided, together with the essential information about the structure of the UCI2001 catalogue and a description of its format. A complete list of the events, as on May 1 2002, is given in the Appendix. (author)

  17. Synthesis of three-dimensional mesoporous Cu-Al layered double hydroxide/g-C3N4 nanocomposites on Ni-foam for enhanced supercapacitors with excellent long-term cycling stability.

    Science.gov (United States)

    Adhikari, Surya Prasad; Awasthi, Ganesh Prasad; Kim, Kyung-Suk; Park, Chan Hee; Kim, Cheol Sang

    2018-03-26

    In this study, a novel composite of Cu-Al layered double hydroxide (LDH) nanosheets and g-C3N4-covered Ni-foam was fabricated via a simple and facile two-step process. First, g-C3N4 sheets were deposited on Ni-foam by via electrodeposition method on a three-electrode system (Ni-foam@g-C3N4) and then, Cu-Al LDH nanosheets were grown on the Ni-foam via in situ redox reaction using a hydrothermal process (Ni-foam@Cu-Al LDH/g-C3N4). The FE-SEM image confirmed that the Cu-Al LDH nanosheets arose vertically and were anchored on the surface of electrodeposited g-C3N4 sheets, thus generating unique 3D porous interconnected networks. The electrochemical capacitive performances of the as-prepared samples were evaluated by cyclic volatammetry (CV), galvanostatic charge/discharge tests, and electrochemical impedance spectra (EIS) Nyquist plots. The specific capacitances of the Ni-foam@Cu-Al LDH/g-C3N4 nanocomposite measured from the CV curve (770.98 F g-1 at 50 mV s-1) and the galvanostatic charge/discharge curve (831.871 at 0.4 A g-1) were significantly higher than the others. Moreover, the Ni-foam@Cu-Al LDH/g-C3N4 nanocomposite revealed a remarkable high-current capacitive behavior and the capacitance retention could be maintained at 92.71% even after 5000 cycles of CV. Thus, the obtained results demonstrated that the as-prepared nanocomposite has great potential to be used as a novel supercapacitor electrode.

  18. A Catalogue of marine biodiversity indicators

    Directory of Open Access Journals (Sweden)

    Heliana Teixeira

    2016-11-01

    Full Text Available A Catalogue of Marine Biodiversity Indicators was developed with the aim of providing the basis for assessing the environmental status of the marine ecosystems. Useful for the implementation of the Marine Strategy Framework Directive (MSFD, this catalogue allows the navigation of a database of indicators mostly related to biological diversity, non-indigenous species, food webs, and seafloor integrity. Over 600 indicators were compiled, which were developed and used in the framework of different initiatives (e.g. EU policies, research projects and in national and international contexts (e.g. Regional Seas Conventions, and assessments in non-European seas. The catalogue reflects the current scientific capability to address environmental assessment needs by providing a broad coverage of the most relevant indicators for marine biodiversity and ecosystem integrity.The available indicators are reviewed according to their typology, data requirements, development status, geographical coverage, relevance to habitats or biodiversity components, and related human pressures. Through this comprehensive overview, we discuss the potential of the current set of indicators in a wide range of contexts, from large-scale to local environmental programs, and we also address shortcomings in light of current needs.Developed by the DEVOTES Project, the catalogue is freely available through the DEVOTool software application, which provides browsing and query options for the associated metadata. The tool allows extraction of ranked indicator lists best fulfilling selected criteria, enabling users to search for suitable indicators to address a particular biodiversity component, ecosystem feature, habitat or pressure in a marine area of interest.This tool is useful for EU Member States, Regional Sea Conventions, the European Commission, non-governmental organizations, managers, scientists and any person interested in marine environmental assessment. It allows users to

  19. A Catalogue of Marine Biodiversity Indicators

    KAUST Repository

    Teixeira, Heliana; Berg, Torsten; Uusitalo, Laura; Fü rhaupter, Karin; Heiskanen, Anna Stiina; Mazik, Krysia; Lynam, Christopher P.; Neville, Suzanna; Rodriguez, J. German; Papadopoulou, Nadia; Moncheva, Snejana; Churilova, Tanya; Kryvenko, Olga; Krause-Jensen, Dorte; Zaiko, Anastasija; Verí ssimo, Helena; Pantazi, Maria; Carvalho, Susana; Patrí cio, Joana; Uyarra, Maria C.; Borja, À ngel

    2016-01-01

    A Catalogue of Marine Biodiversity Indicators was developed with the aim of providing the basis for assessing the environmental status of the marine ecosystems. Useful for the implementation of the Marine Strategy Framework Directive (MSFD), this catalogue allows the navigation of a database of indicators mostly related to biological diversity, non-indigenous species, food webs, and seafloor integrity. Over 600 indicators were compiled, which were developed and used in the framework of different initiatives (e.g., EU policies, research projects) and in national and international contexts (e.g., Regional Seas Conventions, and assessments in non-European seas). The catalogue reflects the current scientific capability to address environmental assessment needs by providing a broad coverage of the most relevant indicators for marine biodiversity and ecosystem integrity. The available indicators are reviewed according to their typology, data requirements, development status, geographical coverage, relevance to habitats or biodiversity components, and related human pressures. Through this comprehensive overview, we discuss the potential of the current set of indicators in a wide range of contexts, from large-scale to local environmental programs, and we also address shortcomings in light of current needs. Developed by the DEVOTES Project, the catalogue is freely available through the DEVOTool software application, which provides browsing and query options for the associated metadata. The tool allows extraction of ranked indicator lists best fulfilling selected criteria, enabling users to search for suitable indicators to address a particular biodiversity component, ecosystem feature, habitat, or pressure in a marine area of interest. This tool is useful for EU Member States, Regional Sea Conventions, the European Commission, non-governmental organizations, managers, scientists, and any person interested in marine environmental assessment. It allows users to build

  20. A Catalogue of Marine Biodiversity Indicators

    KAUST Repository

    Teixeira, Heliana

    2016-11-04

    A Catalogue of Marine Biodiversity Indicators was developed with the aim of providing the basis for assessing the environmental status of the marine ecosystems. Useful for the implementation of the Marine Strategy Framework Directive (MSFD), this catalogue allows the navigation of a database of indicators mostly related to biological diversity, non-indigenous species, food webs, and seafloor integrity. Over 600 indicators were compiled, which were developed and used in the framework of different initiatives (e.g., EU policies, research projects) and in national and international contexts (e.g., Regional Seas Conventions, and assessments in non-European seas). The catalogue reflects the current scientific capability to address environmental assessment needs by providing a broad coverage of the most relevant indicators for marine biodiversity and ecosystem integrity. The available indicators are reviewed according to their typology, data requirements, development status, geographical coverage, relevance to habitats or biodiversity components, and related human pressures. Through this comprehensive overview, we discuss the potential of the current set of indicators in a wide range of contexts, from large-scale to local environmental programs, and we also address shortcomings in light of current needs. Developed by the DEVOTES Project, the catalogue is freely available through the DEVOTool software application, which provides browsing and query options for the associated metadata. The tool allows extraction of ranked indicator lists best fulfilling selected criteria, enabling users to search for suitable indicators to address a particular biodiversity component, ecosystem feature, habitat, or pressure in a marine area of interest. This tool is useful for EU Member States, Regional Sea Conventions, the European Commission, non-governmental organizations, managers, scientists, and any person interested in marine environmental assessment. It allows users to build

  1. VIRAC: The VVV Infrared Astrometric Catalogue

    OpenAIRE

    Smith, L. C.; Lucas, P. W.; Kurtev, R.; Smart, R.; Minniti, D.; Borissova, J.; Jones, H. R. A; Zhang, Z. H.; Marocco, F.; Peña, C. Contreras; Gromadzki, M.; Kuhn, M. A.; Drew, J. E.; Pinfield, D. J.; Bedin, L. R.

    2017-01-01

    We present VIRAC version 1, a near-infrared proper motion and parallax catalogue of the VISTA VVV survey for 312,587,642 unique sources averaged across all overlapping pawprint and tile images covering 560 deg$^2$ of the bulge of the Milky Way and southern disk. The catalogue includes 119 million high quality proper motion measurements, of which 47 million have statistical uncertainties below 1 mas yr$^{-1}$. In the 11$

  2. Origin and Population Dynamics of a Novel HIV-1 Subtype G Clade Circulating in Cape Verde and Portugal.

    Science.gov (United States)

    de Pina-Araujo, Isabel Inês M; Delatorre, Edson; Guimarães, Monick L; Morgado, Mariza G; Bello, Gonzalo

    2015-01-01

    The human immunodeficiency virus type 1 (HIV-1) subtype G is the most prevalent and second most prevalent HIV-1 clade in Cape Verde and Portugal, respectively; but there is no information about the origin and spatiotemporal dispersal pattern of this HIV-1 clade circulating in those countries. To this end, we used Maximum Likelihood and Bayesian coalescent-based methods to analyze a collection of 578 HIV-1 subtype G pol sequences sampled throughout Portugal, Cape Verde and 11 other countries from West and Central Africa over a period of 22 years (1992 to 2013). Our analyses indicate that most subtype G sequences from Cape Verde (80%) and Portugal (95%) branched together in a distinct monophyletic cluster (here called G(CV-PT)). The G(CV-PT) clade probably emerged after a single migration of the virus out of Central Africa into Cape Verde between the late 1970s and the middle 1980s, followed by a rapid dissemination to Portugal a couple of years later. Reconstruction of the demographic history of the G(CV-PT) clade circulating in Cape Verde and Portugal indicates that this viral clade displayed an initial phase of exponential growth during the 1980s and 1990s, followed by a decline in growth rate since the early 2000s. Our data also indicate that during the exponential growth phase the G(CV-PT) clade recombined with a preexisting subtype B viral strain circulating in Portugal, originating the CRF14_BG clade that was later disseminated to Spain and Cape Verde. Historical and recent human population movements between Angola, Cape Verde and Portugal probably played a key role in the origin and dispersal of the G(CV-PT )and CRF14_BG clades.

  3. CvADH1, a member of short-chain alcohol dehydrogenase family, is inducible by gibberellin and sucrose in developing watermelon seeds.

    Science.gov (United States)

    Kim, Joonyul; Kang, Hong-Gyu; Jun, Sung-Hoon; Lee, Jinwon; Yim, Jieun; An, Gynheung

    2003-01-01

    To understand the molecular mechanisms that control seed formation, we selected a seed-preferential gene (CvADH1) from the ESTs of developing watermelon seeds. RNA blot analysis and in situ localization showed that CvADH1 was preferentially expressed in the nucellar tissue. The CvADH1 protein shared about 50% homology with short-chain alcohol dehydrogenase including ABA2 in Arabidopsis thaliana, stem secoisolariciresinol dehydrogenase in Forsythia intermedia, and 3beta-hydroxysterol dehydrogenase in Digitalis lanata. We investigated gene-expression levels in seeds from both normally pollinated fruits and those made parthenocarpic via N-(2-chloro-4-pyridyl)-N'-phenylurea treatment, the latter of which lack zygotic tissues. Whereas the transcripts of CvADH1 rapidly started to accumulate from about the pre-heart stage in normal seeds, they were not detectable in the parthenocarpic seeds. Treating the parthenogenic fruit with GA(3) strongly induced gene expression, up to the level accumulated in pollinated seeds. These results suggest that the CvADH1 gene is induced in maternal tissues by signals made in the zygotic tissues, and that gibberellin might be one of those signals. We also observed that CvADH1 expression was induced by sucrose in the parthenocarpic seeds. Therefore, we propose that the CvADH1 gene is inducible by gibberellin, and that sucrose plays an important role in the maternal tissues of watermelon during early seed development.

  4. Netherlands Oil and Gas Catalogue 2010

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-04-15

    The Netherlands Oil and Gas Catalogue 2010 is a specialist publication from IRO (the Association of Dutch Suppliers in the Oil and Gas Industry) and Pedemex. A wealth of relevant business information has been collected with the greatest care to be included in this publication, and subsequently brought together in an easy to digest order. The catalogue is broken down into the following headings: (1) Engineering, Consultancy and Research; (2) Exploration, Drilling and Production; (3) Construction and Fabrication; (4) Contracting,Transport and Installation; (5) Equipment Supply; (6) Miscellaneous. In addition you can by using keywords, rapidly identify the company you are looking for. A list is also enclosed with the names and contact details of IRO members, and the sectors in which they are active.

  5. Alcohol promotions in Australian supermarket catalogues.

    Science.gov (United States)

    Johnston, Robyn; Stafford, Julia; Pierce, Hannah; Daube, Mike

    2017-07-01

    In Australia, most alcohol is sold as packaged liquor from off-premises retailers, a market increasingly dominated by supermarket chains. Competition between retailers may encourage marketing approaches, for example, discounting, that evidence indicates contribute to alcohol-related harms. This research documented the nature and variety of promotional methods used by two major supermarket retailers to promote alcohol products in their supermarket catalogues. Weekly catalogues from the two largest Australian supermarket chains were reviewed for alcohol-related content over 12 months. Alcohol promotions were assessed for promotion type, product type, number of standard drinks, purchase price and price/standard drink. Each store catalogue included, on average, 13 alcohol promotions/week, with price-based promotions most common. Forty-five percent of promotions required the purchase of multiple alcohol items. Wine was the most frequently promoted product (44%), followed by beer (24%) and spirits (18%). Most (99%) wine cask (2-5 L container) promotions required multiple (two to three) casks to be purchased. The average number of standard drinks required to be purchased to participate in catalogue promotions was 31.7 (SD = 24.9; median = 23.1). The median price per standard drink was $1.49 (range $0.19-$9.81). Cask wines had the lowest cost per standard drink across all product types. Supermarket catalogues' emphasis on low prices/high volumes of alcohol reflects that retailers are taking advantage of limited restrictions on off-premise sales and promotion, which allow them to approach market competition in ways that may increase alcohol-related harms in consumers. Regulation of alcohol marketing should address retailer catalogue promotions. [Johnston R, Stafford J, Pierce H, Daube M. Alcohol promotions in Australian supermarket catalogues. Drug Alcohol Rev 2017;36:456-463]. © 2016 Australasian Professional Society on Alcohol and other Drugs.

  6. Research and characterisation of blazar candidates among the Fermi/LAT 3FGL catalogue using multivariate classifications

    Science.gov (United States)

    Lefaucheur, Julien; Pita, Santiago

    2017-06-01

    Context. In the recently published 3FGL catalogue, the Fermi/LAT collaboration reports the detection of γ-ray emission from 3034 sources obtained after four years of observations. The nature of 1010 of those sources is unknown, whereas 2023 have well-identified counterparts in other wavelengths. Most of the associated sources are labelled as blazars (1717/2023), but the BL Lac or FSRQ nature of 573 of these blazars is still undetermined. Aims: The aim of this study was two-fold. First, to significantly increase the number of blazar candidates from a search among the large number of Fermi/LAT 3FGL unassociated sources (case A). Second, to determine the BL Lac or FSRQ nature of the blazar candidates, including those determined as such in this work and the blazar candidates of uncertain type (BCU) that are already present in the 3FGL catalogue (case B). Methods: For this purpose, multivariate classifiers - boosted decision trees and multilayer perceptron neural networks - were trained using samples of labelled sources with no caution flag from the 3FGL catalogue and carefully chosen discriminant parameters. The decisions of the classifiers were combined in order to obtain a high level of source identification along with well controlled numbers of expected false associations. Specifically for case A, dedicated classifications were generated for high (| b | >10◦) and low (| b | ≤10◦) galactic latitude sources; in addition, the application of classifiers to samples of sources with caution flag was considered separately, and specific performance metrics were estimated. Results: We obtained a sample of 595 blazar candidates (high and low galactic latitude) among the unassociated sources of the 3FGL catalogue. We also obtained a sample of 509 BL Lacs and 295 FSRQs from the blazar candidates cited above and the BCUs of the 3FGL catalogue. The number of expected false associations is given for different samples of candidates. It is, in particular, notably low ( 9

  7. Users and Union Catalogues

    Science.gov (United States)

    Hartley, R. J.; Booth, Helen

    2006-01-01

    Union catalogues have had an important place in libraries for many years. Their use has been little investigated. Recent interest in the relative merits of physical and virtual union catalogues and a recent collaborative project between a physical and several virtual union catalogues in the United Kingdom led to the opportunity to study how users…

  8. Clinical outcome of chemoradiotherapy for T1G3 bladder cancer

    International Nuclear Information System (INIS)

    Inoue, Masaharu; Ishioka, Jun-ichiro; Fukuda, Hiroshi; Kageyama, Yukio; Saito, Yoshihiro; Higashi, Yotsuo

    2008-01-01

    The aim of this study was to determine the clinical outcome of a bladder-sparing approach using chemoradiotherapy (CRT) for T1G3 bladder cancer. Between May 2000 and August 2007, 11 patients with T1G3 bladder cancer and who were negative for macroscopic residual tumor were treated by CRT after transurethral resection of bladder tumor (TUR-Bt). Pelvic irradiation was given at a dose of 40 Gy in 4 weeks. Intra-arterial administration of cisplatin and systemic administration of methotrexate were carried out in the first and third weeks of radiotherapy. One month after CRT, response was evaluated by restaging TUR-Bt. For persistent tumor after CRT or tumor recurrence, patients received additional treatment. Median follow-up was 21.2 months. Complete response was achieved in 10 of 11 patients (90.9%). Local recurrence for the entire group of 11 patients was 22.1% at both 2 and 5 years. Tumor progression was 0% at 5 years. Disease-specific survival rates were 100% at 5 years. All of survivors retained functioning bladders. Bladder preservation by CRT is a curative treatment option for T1G3 bladder cancer and a reasonable alternative to intravesical treatment or early cystectomy. (author)

  9. The IKEA Catalogue

    DEFF Research Database (Denmark)

    Brown, Barry; Bleecker, Julian; D'Adamo, Marco

    2016-01-01

    This paper is an introduction to the "Future IKEA Catalogue", enclosed here as an example of a design fiction produced from a long standing industrial-academic collaboration. We introduce the catalogue here by discussing some of our experiences using design fiction` with companies and public sector...

  10. Catalogue of theses

    International Nuclear Information System (INIS)

    Paranjpe, S.V.

    1975-01-01

    The catalogue lists 442 theses submitted by the scientists of the Bhabha Atomic Research Centre, since its inception, to the various universities in India and abroad for the award of M. Sc. and Ph. D. degrees. Theses are grouped under broad subject headings which are arranged in the order of Universal Decimal Classification Scheme. In addition to the author and guide index, a detailed subject index is appended which enhances the utility of the compilation. (S.V.P.)

  11. Updated earthquake catalogue for seismic hazard analysis in Pakistan

    Science.gov (United States)

    Khan, Sarfraz; Waseem, Muhammad; Khan, Muhammad Asif; Ahmed, Waqas

    2018-03-01

    A reliable and homogenized earthquake catalogue is essential for seismic hazard assessment in any area. This article describes the compilation and processing of an updated earthquake catalogue for Pakistan. The earthquake catalogue compiled in this study for the region (quadrangle bounded by the geographical limits 40-83° N and 20-40° E) includes 36,563 earthquake events, which are reported as 4.0-8.3 moment magnitude (M W) and span from 25 AD to 2016. Relationships are developed between the moment magnitude and body, and surface wave magnitude scales to unify the catalogue in terms of magnitude M W. The catalogue includes earthquakes from Pakistan and neighbouring countries to minimize the effects of geopolitical boundaries in seismic hazard assessment studies. Earthquakes reported by local and international agencies as well as individual catalogues are included. The proposed catalogue is further used to obtain magnitude of completeness after removal of dependent events by using four different algorithms. Finally, seismicity parameters of the seismic sources are reported, and recommendations are made for seismic hazard assessment studies in Pakistan.

  12. Cultivation of CNPA G3 sesame irrigated with saline water and fertilized with nitrate-N and ammonium-N

    Directory of Open Access Journals (Sweden)

    Geovani S. de Lima

    Full Text Available ABSTRACT The study aimed to evaluate the effects of irrigation with saline water and fertilization with nitrate (NO3--N and ammonium (NH4+-N ratios on growth, flowering, water consumption and water use efficiency of the sesame cv. CNPA G3. The treatments were distributed in randomized blocks in a 5 x 5 factorial with three replicates, referring to five levels of electrical conductivity of the irrigation water - ECw (0.6, 1.2, 1.8, 2.4 and 3.0 dS m-1 and nitrate (NO3--N and ammonium (NH4+-N (200/0, 150/50, 100/100, 50/150, 0/200 mg kg-1 ratios. Irrigation with saline water above 0.6 dS m-1 inhibited the growth, delayed flowering and promoted early maturation of capsules of sesame, cv. CNPA G3. The proportion of 0/200 mg kg-1 of NO3--N/NH4+-N promoted the greatest increase relative to stem diameter and height of sesame plants. Water consumption decreases with increasing ECw and was significantly lower in plants fertilized with the proportion of 0/200 of NO3--N/NH4+-N. The interaction between ECw levels and ammonium/nitrate proportions significantly affect water use efficiency, and the highest value was obtained with ECw of 0.6 dS m-1 and fertilization with 150:50 mg kg-1 of NO3--N and NH4+-N.

  13. Chest compression during sustained inflation versus 3:1 chest compression:ventilation ratio during neonatal cardiopulmonary resuscitation: a randomised feasibility trial.

    Science.gov (United States)

    Schmölzer, Georg M; O Reilly, Megan; Fray, Caroline; van Os, Sylvia; Cheung, Po-Yin

    2017-10-07

    Current neonatal resuscitation guidelines recommend 3:1 compression:ventilation (C:V) ratio. Recently, animal studies reported that continuous chest compressions (CC) during a sustained inflation (SI) significantly improved return of spontaneous circulation (ROSC). The approach of CC during SI (CC+SI) has not been examined in the delivery room during neonatal resuscitation. It is a feasibility study to compare CC+SI versus 3:1 C:V ratio during neonatal resuscitation in the delivery room. We hypothesised that during neonatal resuscitation, CC+SI will reduce the time to ROSC. Our aim was to examine if CC+SI reduces ROSC compared with 3:1 C:V CPR in preterm infants rate of 90/min during an SI with a duration of 20 s (CC+SI). After 20 s, the SI was interrupted for 1 s and the next SI was started for another 20 s until ROSC. Infants in the '3:1 group' received CC using 3:1 C:V ratio until ROSC. Overall the mean (SD) time to ROSC was significantly shorter in the CC+SI group with 31 (9) s compared with 138 (72) s in the 3:1 C:V group (p=0.011). CC+SI is feasible in the delivery room. Clinicaltrials.gov NCT02083705, pre-results. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  14. On Hydronymic Catalogues Composition Principles: Cataloguing of Hydronyms of the Msta River Basin

    OpenAIRE

    Valery L. Vasilyev; Nina N. Vikhrova

    2015-01-01

    The article presents a brief review of the few Russian hydronymic catalogues (relating to the basins of the Don, Oka, Svir and other rivers) based on the hydrographic principle. The authors argue that, in comparison with alphabetized hydronymic dictionaries, hydronymic catalogues have some obvious advantages for onomastic lexicography. This kind of catalogues should include, firstly, all historically attested forms of a hydronym (including those considered to be occasional miswritings) and, s...

  15. Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA

    OpenAIRE

    Friew, Yeshitila N; Boyko, Vitaly; Hu, Wei-Shau; Pathak, Vinay K

    2009-01-01

    Abstract Background Host restriction factor APOBEC3G (A3G) blocks human immunodeficiency virus type 1 (HIV-1) replication by G-to-A hypermutation, and by inhibiting DNA synthesis and provirus formation. Previous reports have suggested that A3G is a dimer and its virion incorporation is mediated through interactions with viral or nonviral RNAs and/or HIV-1 Gag. We have now employed a bimolecular fluorescence complementation assay (BiFC) to analyze the intracellular A3G-A3G, A3G-RNA, and A3G-Ga...

  16. Astrometry with A-Track Using Gaia DR1 Catalogue

    Science.gov (United States)

    Kılıç, Yücel; Erece, Orhan; Kaplan, Murat

    2018-04-01

    In this work, we built all sky index files from Gaia DR1 catalogue for the high-precision astrometric field solution and the precise WCS coordinates of the moving objects. For this, we used build-astrometry-index program as a part of astrometry.net code suit. Additionally, we added astrometry.net's WCS solution tool to our previously developed software which is a fast and robust pipeline for detecting moving objects such as asteroids and comets in sequential FITS images, called A-Track. Moreover, MPC module was added to A-Track. This module is linked to an asteroid database to name the found objects and prepare the MPC file to report the results. After these innovations, we tested a new version of the A-Track code on photometrical data taken by the SI-1100 CCD with 1-meter telescope at TÜBİTAK National Observatory, Antalya. The pipeline can be used to analyse large data archives or daily sequential data. The code is hosted on GitHub under the GNU GPL v3 license.

  17. On Hydronymic Catalogues Composition Principles: Cataloguing of Hydronyms of the Msta River Basin

    Directory of Open Access Journals (Sweden)

    Valery L. Vasilyev

    2015-06-01

    Full Text Available The article presents a brief review of the few Russian hydronymic catalogues (relating to the basins of the Don, Oka, Svir and other rivers based on the hydrographic principle. The authors argue that, in comparison with alphabetized hydronymic dictionaries, hydronymic catalogues have some obvious advantages for onomastic lexicography. This kind of catalogues should include, firstly, all historically attested forms of a hydronym (including those considered to be occasional miswritings and, secondly, all non-hydronymic names making part of the respective hydronymic microsystem and providing “external” (i. e., chronological, derivational, etymological, ethno-historical information about the hydronym. The authors point out that the cataloguing of hydronyms based on the hydrographic principle entails some difficulties: impossibility to localize some bodies of water mentioned in ancient and medieval documents; differences in the indication of the same bodies of water on old and contemporary maps; historical differences in establishing hydrographic hierarchies; historical changes of lake-river systems, etc. The authors also share their experience in creating a hydronymic catalogue of the Msta River basin in Novgorod and Tver Regions of Russia. They describe the principles of the composition of the catalogue and present a short excerpt of it that orders names in the system of the Volma River, one of the Msta’s left tributaries.

  18. CERES ERBE-like Instantaneous TOA Estimates (ES-8) in HDF (CER_ES8_Aqua-FM4_Edition1-CV)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    The ES-8 archival data product contains a 24-hour, single-satellite, instantaneous view of scanner fluxes at the top-of-atmosphere (TOA) reduced from spacecraft altitude unfiltered radiances using Earth Radiation Budget Experiment (ERBE) scanner Inversion algorithms and the ERBE shortwave (SW) and longwave (LW) Angular Distribution Models (ADMs). The ES-8 also includes the total (TOT), SW, LW, and window (WN) channel radiometric data; SW, LW, and WN unfiltered radiance values; and the ERBE scene identification for each measurement. These data are organized according to the CERES 3.3-second scan into 6.6-second records. As long as there is one valid scanner measurement within a record, the ES-8 record will be generated. The following CERES ES8 data sets are currently available: CER_ES8_TRMM-PFM_Edition1 CER_ES8_TRMM-PFM_Edition2 CER_ES8_TRMM-PFM_Transient-Ops2 CER_ES8_Terra-FM1_Edition1 CER_ES8_Terra-FM2_Edition1 CER_ES8_Terra-FM1_Edition2 CER_ES8_Terra-FM2_Edition2 CER_ES8_Aqua-FM3_Edition1 CER_ES8_Aqua-FM4_Edition1 CER_ES8_Aqua-FM3_Edition2 CER_ES8_Aqua-FM4_Edition2 CER_ES8_Aqua-FM3_Edition1-CV CER_ES8_Aqua-FM4_Edition1-CV CER_ES8_Terra-FM1_Edition1-CV CER_ES8_Terra-FM1_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2005-03-29] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

  19. Grid Enabled Geospatial Catalogue Web Service

    Science.gov (United States)

    Chen, Ai-Jun; Di, Li-Ping; Wei, Ya-Xing; Liu, Yang; Bui, Yu-Qi; Hu, Chau-Min; Mehrotra, Piyush

    2004-01-01

    Geospatial Catalogue Web Service is a vital service for sharing and interoperating volumes of distributed heterogeneous geospatial resources, such as data, services, applications, and their replicas over the web. Based on the Grid technology and the Open Geospatial Consortium (0GC) s Catalogue Service - Web Information Model, this paper proposes a new information model for Geospatial Catalogue Web Service, named as GCWS which can securely provides Grid-based publishing, managing and querying geospatial data and services, and the transparent access to the replica data and related services under the Grid environment. This information model integrates the information model of the Grid Replica Location Service (RLS)/Monitoring & Discovery Service (MDS) with the information model of OGC Catalogue Service (CSW), and refers to the geospatial data metadata standards from IS0 19115, FGDC and NASA EOS Core System and service metadata standards from IS0 191 19 to extend itself for expressing geospatial resources. Using GCWS, any valid geospatial user, who belongs to an authorized Virtual Organization (VO), can securely publish and manage geospatial resources, especially query on-demand data in the virtual community and get back it through the data-related services which provide functions such as subsetting, reformatting, reprojection etc. This work facilitates the geospatial resources sharing and interoperating under the Grid environment, and implements geospatial resources Grid enabled and Grid technologies geospatial enabled. It 2!so makes researcher to focus on science, 2nd not cn issues with computing ability, data locztic, processir,g and management. GCWS also is a key component for workflow-based virtual geospatial data producing.

  20. APOBEC3G inhibits elongation of HIV-1 reverse transcripts.

    Directory of Open Access Journals (Sweden)

    Kate N Bishop

    2008-12-01

    Full Text Available APOBEC3G (A3G is a host cytidine deaminase that, in the absence of Vif, restricts HIV-1 replication and reduces the amount of viral DNA that accumulates in cells. Initial studies determined that A3G induces extensive mutation of nascent HIV-1 cDNA during reverse transcription. It has been proposed that this triggers the degradation of the viral DNA, but there is now mounting evidence that this mechanism may not be correct. Here, we use a natural endogenous reverse transcriptase assay to show that, in cell-free virus particles, A3G is able to inhibit HIV-1 cDNA accumulation not only in the absence of hypermutation but also without the apparent need for any target cell factors. We find that although reverse transcription initiates in the presence of A3G, elongation of the cDNA product is impeded. These data support the model that A3G reduces HIV-1 cDNA levels by inhibiting synthesis rather than by inducing degradation.

  1. Planck 2013 results. XXIX. Planck catalogue of Sunyaev-Zeldovich sources

    CERN Document Server

    Ade, P.A.R.; Armitage-Caplan, C.; Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Aussel, H.; Baccigalupi, C.; Banday, A.J.; Barreiro, R.B.; Barrena, R.; Bartelmann, M.; Bartlett, J.G.; Battaner, E.; Benabed, K.; Benoit, A.; Benoit-Levy, A.; Bernard, J.P.; Bersanelli, M.; Bielewicz, P.; Bikmaev, I.; Bobin, J.; Bock, J.J.; Bohringer, H.; Bonaldi, A.; Bond, J.R.; Borrill, J.; Bouchet, F.R.; Bridges, M.; Bucher, M.; Burenin, R.; Burigana, C.; Butler, R.C.; Cardoso, J.F.; Carvalho, P.; Catalano, A.; Challinor, A.; Chamballu, A.; Chary, R.R.; Chen, X.; Chiang, L.Y.; Chiang, H.C.; Chon, G.; Christensen, P.R.; Churazov, E.; Church, S.; Clements, D.L.; Colombi, S.; Colombo, L.P.L.; Comis, B.; Couchot, F.; Coulais, A.; Crill, B.P.; Curto, A.; Cuttaia, F.; Da Silva, A.; Dahle, H.; Danese, L.; Davies, R.D.; Davis, R.J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Delouis, J.M.; Democles, J.; Desert, F.X.; Dickinson, C.; Diego, J.M.; Dolag, K.; Dole, H.; Donzelli, S.; Dore, O.; Douspis, M.; Dupac, X.; Efstathiou, G.; Ensslin, T.A.; Eriksen, H.K.; Feroz, F.; Finelli, F.; Flores-Cacho, I.; Forni, O.; Frailis, M.; Franceschi, E.; Fromenteau, S.; Galeotta, S.; Ganga, K.; Genova-Santos, R.T.; Giard, M.; Giardino, G.; Gilfanov, M.; Giraud-Heraud, Y.; Gonzalez-Nuevo, J.; Gorski, K.M.; Grainge, K.J.B.; Gratton, S.; Gregorio, A.; N, E.Groeneboom; Gruppuso, A.; Hansen, F.K.; Hanson, D.; Harrison, D.; Hempel, A.; Henrot-Versille, S.; Hernandez-Monteagudo, C.; Herranz, D.; Hildebrandt, S.R.; Hivon, E.; Hobson, M.; Holmes, W.A.; Hornstrup, A.; Hovest, W.; Huffenberger, K.M.; Hurier, G.; Hurley-Walker, N.; Jaffe, T.R.; Jaffe, A.H.; Jones, W.C.; Juvela, M.; Keihanen, E.; Keskitalo, R.; Khamitov, I.; Kisner, T.S.; Kneissl, R.; Knoche, J.; Knox, L.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lahteenmaki, A.; Lamarre, J.M.; Lasenby, A.; Laureijs, R.J.; Lawrence, C.R.; Leahy, J.P.; Leonardi, R.; Leon-Tavares, J.; Lesgourgues, J.; Li, C.; Liddle, A.; Liguori, M.; Lilje, P.B.; Linden-Vornle, M.; Lopez-Caniego, M.; Lubin, P.M.; Macias-Perez, J.F.; MacTavish, C.J.; Maffei, B.; Maino, D.; Mandolesi, N.; Maris, M.; Marshall, D.J.; Martin, P.G.; Martinez-Gonzalez, E.; Masi, S.; Matarrese, S.; Matthai, F.; Mazzotta, P.; Mei, S.; Meinhold, P.R.; Melchiorri, A.; Melin, J.B.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschenes, M.A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Naselsky, P.; Nati, F.; Natoli, P.; Nesvadba, N.P.H.; Netterfield, C.B.; Norgaard-Nielsen, H.U.; Noviello, F.; Novikov, D.; Novikov, I.; O'Dwyer, I.J.; Olamaie, M.; Osborne, S.; Oxborrow, C.A.; Paci, F.; Pagano, L.; Pajot, F.; Paoletti, D.; Pasian, F.; Patanchon, G.; Pearson, T.J.; Perdereau, O.; Perotto, L.; Perrott, Y.C.; Perrotta, F.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Popa, L.; Poutanen, T.; Pratt, G.W.; Prezeau, G.; Prunet, S.; Puget, J.L.; Rachen, J.P.; Reach, W.T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Roudier, G.; Rowan-Robinson, M.; Rubino-Martin, J.A.; Rumsey, C.; Rusholme, B.; Sandri, M.; Santos, D.; Saunders, R.D.E.; Savini, G.; Scott, D.; Seiffert, M.D.; Shellard, E.P.S.; Shimwell, T.W.; Spencer, L.D.; Starck, J.L.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sunyaev, R.; Sureau, F.; Sutton, D.; Suur-Uski, A.S.; Sygnet, J.F.; Tauber, J.A.; Tavagnacco, D.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Turler, M.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vibert, L.; Vielva, P.; Villa, F.; Vittorio, N.; Wade, L.A.; Wandelt, B.D.; White, M.; White, S.D.M.; Yvon, D.; Zacchei, A.; Zonca, A.

    2014-01-01

    We describe the all-sky Planck catalogue of clusters and cluster candidates derived from Sunyaev--Zeldovich (SZ) effect detections using the first 15.5 months of Planck satellite observations. The catalogue contains 1227 entries, making it over six times the size of the Planck Early SZ (ESZ) sample and the largest SZ-selected catalogue to date. It contains 861 confirmed clusters, of which 178 have been confirmed as clusters, mostly through follow-up observations, and a further 683 are previously-known clusters. The remaining 366 have the status of cluster candidates, and we divide them into three classes according to the quality of evidence that they are likely to be true clusters. The Planck SZ catalogue is the deepest all-sky cluster catalogue, with redshifts up to about one, and spans the broadest cluster mass range from (0.1 to 1.6) 10^{15}Msun. Confirmation of cluster candidates through comparison with existing surveys or cluster catalogues is extensively described, as is the statistical characterization...

  2. Planck 2015 results. XXVIII. The Planck Catalogue of Galactic Cold Clumps

    CERN Document Server

    Ade, P.A.R.; Arnaud, M.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Banday, A.J.; Barreiro, R.B.; Bartolo, N.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bonaldi, A.; Bonavera, L.; Bond, J.R.; Borrill, J.; Bouchet, F.R.; Boulanger, F.; Bucher, M.; Burigana, C.; Butler, R.C.; Calabrese, E.; Catalano, A.; Chamballu, A.; Chiang, H.C.; Christensen, P.R.; Clements, D.L.; Colombi, S.; Colombo, L.P.L.; Combet, C.; Couchot, F.; Coulais, A.; Crill, B.P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R.D.; Davis, R.J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Désert, F.-X.; Dickinson, C.; Diego, J.M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T.A.; Eriksen, H.K.; Falgarone, E.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A.A.; Franceschi, E.; Frejsel, A.; Galeotta, S.; Galli, S.; Ganga, K.; Giard, M.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K.M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J.E.; Hansen, F.K.; Hanson, D.; Harrison, D.L.; Helou, G.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S.R.; Hivon, E.; Hobson, M.; Holmes, W.A.; Hornstrup, A.; Hovest, W.; Huffenberger, K.M.; Hurier, G.; Jaffe, A.H.; Jaffe, T.R.; Jones, W.C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kisner, T.S.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Lawrence, C.R.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Liguori, M.; Lilje, P.B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P.M.; Macías-Pérez, J.F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Marshall, D.J.; Martin, P.G.; Martínez-González, E.; Masi, S.; Matarrese, S.; Mazzotta, P.; McGehee, P.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschênes, M.-A.; Moneti, A.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Murphy, J.A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C.B.; Nørgaard-Nielsen, H.U.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C.A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Paoletti, D.; Pasian, F.; Patanchon, G.; Pearson, T.J.; Pelkonen, V.-M.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Pratt, G.W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J.P.; Reach, W.T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rubiño-Martín, J.A.; Rusholme, B.; Sandri, M.; Santos, D.; Savelainen, M.; Savini, G.; Scott, D.; Seiffert, M.D.; Shellard, E.P.S.; Spencer, L.D.; Stolyarov, V.; Sudiwala, R.; Sunyaev, R.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J.A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vielva, P.; Villa, F.; Wade, L.A.; Wandelt, B.D.; Wehus, I.K.; Yvon, D.; Zacchei, A.

    2016-01-01

    We present the Planck Catalogue of Galactic Cold Clumps (PGCC), an all-sky catalogue of Galactic cold clump candidates detected by Planck. This catalogue is the full version of the Early Cold Core (ECC) catalogue, which was made available in 2011 with the Early Release Compact Source Catalogue (ERCSC) and contained 915 high S/N sources. It is based on the Planck 48 months mission data that are currently being released to the astronomical community. The PGCC catalogue is an observational catalogue consisting exclusively of Galactic cold sources. The three highest Planck bands (857, 545, 353 GHz) have been combined with IRAS data at 3 THz to perform a multi-frequency detection of sources colder than their local environment. After rejection of possible extragalactic contaminants, the PGCC catalogue contains 13188 Galactic sources spread across the whole sky, i.e., from the Galactic plane to high latitudes, following the spatial distribution of the main molecular cloud complexes. The median temperature of PGCC so...

  3. Multifaceted counter-APOBEC3G mechanisms employed by HIV-1 Vif.

    Science.gov (United States)

    Britan-Rosich, Elena; Nowarski, Roni; Kotler, Moshe

    2011-07-29

    In the absence of human immunodeficiency virus type 1 (HIV-1) Vif protein, the host antiviral deaminase apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (A3G) restricts the production of infectious HIV-1 by deamination of dC residues in the negative single-stranded DNA produced by reverse transcription. The Vif protein averts the lethal threat of deamination by precluding the packaging of A3G into assembling virions by mediating proteasomal degradation of A3G. In spite of this robust Vif activity, residual A3G molecules that escape degradation and incorporate into newly assembled virions are potentially deleterious to the virus. We hypothesized that virion-associated Vif inhibits A3G enzymatic activity and therefore prevents lethal mutagenesis of the newly synthesized viral DNA. Here, we show that (i) Vif-proficient HIV-1 particles released from H9 cells contain A3G with lower specific activity compared with Δvif-virus-associated A3G, (ii) encapsidated HIV-1 Vif inhibits the deamination activity of recombinant A3G, and (iii) purified HIV-1 Vif protein and the Vif-derived peptide Vif25-39 inhibit A3G activity in vitro at nanomolar concentrations in an uncompetitive manner. Our results manifest the potentiality of Vif to control the deamination threat in virions or in the pre-integration complexes following entry to target cells. Hence, virion-associated Vif could serve as a last line of defense, protecting the virus against A3G antiviral activity. Copyright © 2011 Elsevier Ltd. All rights reserved.

  4. The two union catalogues of Myanmar

    Energy Technology Data Exchange (ETDEWEB)

    Hla, Win [Myanmar Scientific and Technological Research Dept., Yangon (Myanmar)

    1995-04-01

    The article mentions about the two union catalogues of Myanmar. The first one is the ``Consolidated Catalogue of journals and the periodicals contained in the libraries of Kasuali, Calcutta, Bombay, Madras, Coonoor, Rangoon and Shillong``. This was published by Indian Research Fund Association of Calcutta in 1933. This is the first union catalogue of medical periodicals for both Myanmar and India as well. The second one is ``the Regional Union Catalogue of Scientific Serials: Yangon``. This was published in 1977, its second printing in 1989. This union catalogue excludes medical serials. Twenty libraries took part in the compilation and publishing of the union catalogue with Technical Information Centre of Myanmar Scientific and Technological Research Department, (formerly Central Research Organization), No. 6, Kaba Aye Pagoda Road, Yankin P.O. Yangon, Myanmar, taking the leading role.

  5. The two union catalogues of Myanmar

    International Nuclear Information System (INIS)

    Hla, Win

    1995-01-01

    The article mentions about the two union catalogues of Myanmar. The first one is the ''Consolidated Catalogue of journals and the periodicals contained in the libraries of Kasuali, Calcutta, Bombay, Madras, Coonoor, Rangoon and Shillong''. This was published by Indian Research Fund Association of Calcutta in 1933. This is the first union catalogue of medical periodicals for both Myanmar and India as well. The second one is ''the Regional Union Catalogue of Scientific Serials: Yangon''. This was published in 1977, its second printing in 1989. This union catalogue excludes medical serials. Twenty libraries took part in the compilation and publishing of the union catalogue with Technical Information Centre of Myanmar Scientific and Technological Research Department, (formerly Central Research Organization), No. 6, Kaba Aye Pagoda Road, Yankin P.O. Yangon, Myanmar, taking the leading role

  6. Second ROSAT all-sky survey (2RXS) source catalogue

    Science.gov (United States)

    Boller, Th.; Freyberg, M. J.; Trümper, J.; Haberl, F.; Voges, W.; Nandra, K.

    2016-04-01

    Aims: We present the second ROSAT all-sky survey source catalogue, hereafter referred to as the 2RXS catalogue. This is the second publicly released ROSAT catalogue of point-like sources obtained from the ROSAT all-sky survey (RASS) observations performed with the position-sensitive proportional counter (PSPC) between June 1990 and August 1991, and is an extended and revised version of the bright and faint source catalogues. Methods: We used the latest version of the RASS processing to produce overlapping X-ray images of 6.4° × 6.4° sky regions. To create a source catalogue, a likelihood-based detection algorithm was applied to these, which accounts for the variable point-spread function (PSF) across the PSPC field of view. Improvements in the background determination compared to 1RXS were also implemented. X-ray control images showing the source and background extraction regions were generated, which were visually inspected. Simulations were performed to assess the spurious source content of the 2RXS catalogue. X-ray spectra and light curves were extracted for the 2RXS sources, with spectral and variability parameters derived from these products. Results: We obtained about 135 000 X-ray detections in the 0.1-2.4 keV energy band down to a likelihood threshold of 6.5, as adopted in the 1RXS faint source catalogue. Our simulations show that the expected spurious content of the catalogue is a strong function of detection likelihood, and the full catalogue is expected to contain about 30% spurious detections. A more conservative likelihood threshold of 9, on the other hand, yields about 71 000 detections with a 5% spurious fraction. We recommend thresholds appropriate to the scientific application. X-ray images and overlaid X-ray contour lines provide an additional user product to evaluate the detections visually, and we performed our own visual inspections to flag uncertain detections. Intra-day variability in the X-ray light curves was quantified based on the

  7. Profile catalogue for airfoil sections based on 3D computations

    DEFF Research Database (Denmark)

    Bertagnolio, F.; Sørensen, Niels N.; Johansen, Jeppe

    2006-01-01

    This report is a continuation of the Wind Turbine Airfoil Catalogue [1] which objective was, firstly to provide a database of aerodynamic characteristics for a wide range of airfoil profiles aimed at wind turbine applications, and secondly to test thetwo-dimensional Navier-Stokes solver EllipSys2D...... and the actual fluid flow, and thereby the incorrect prediction of airfoil characteristics. In addition, other features of the flow solver, such astransition and turbulence modelling, and their influence onto the numerical results are investigated. Conclusions are drawn regarding the evaluation of airfoil...

  8. Fox grape cv. Bordô (Vitis labrusca L. and grapevine cv. Chardonnay (Vitis vinifera L. cultivated in vitro under different carbohydrates, amino acids and 6-Benzylaminopurine levels

    Directory of Open Access Journals (Sweden)

    Dayse Cristina de Carvalho

    2013-04-01

    Full Text Available The aim of this work was to study the influence of sucrose and glucose, amino acids and BAP (6-Benzylaminopurine levels on in vitro shoot regeneration of fox grape cv. Bordô and grapevine cv. Chardonnay. The nodal segments from micropropagated material were used as explants and half-strength MS medium as the basal medium. Sucrose and glucose at 15, 30 and 45 g.L-1 were tested as a carbon source and the supplementation of adenine, asparagine, alanine, glycine, cysteine, glutamine, arginine was tested at 40 g.L-1. The BAP levels (1 and 5 μM in solid and double-phase media were evaluated and compared with a control medium without BAP. Bordô had best in vitro growth than Chardonnay. Sucrose was a better carbohydrate source than glucose for both the cultivars. Bordô and Chardonnay had different amino acid preferences for some parameters. In conclusion, for in vitro shoot regeneration from the nodal segments, culture on solid medium with 5 μM BAP, 15 g.L-1 sucrose for Bordô and 45 g.L-1 sucrose for Chardonnay showed better results. Similarly, the supplementation of 40 g.L-1 arginine for Bordô and 40 g.L-1 arginine or glycine for Chardonnay showed better results.

  9. Distributed Multi-interface Catalogue for Geospatial Data

    Science.gov (United States)

    Nativi, S.; Bigagli, L.; Mazzetti, P.; Mattia, U.; Boldrini, E.

    2007-12-01

    inventory systems. Prominent features include: 1)Support to distributed queries over a hierarchical data model, supporting incremental queries (i.e. query over collections, to be subsequently refined) and opaque/translucent chaining; 2)Support to several client protocols, through a compound front-end interface module. This allows to accommodate a (growing) number of cataloguing standards, or profiles thereof, including the OGC CSW interface, ebRIM Application Profile (for Core ISO Metadata and other data models), and the ISO Application Profile. The presented catalog clearinghouse supports both the opaque and translucent pattern for service chaining. In fact, the clearinghouse catalog may be configured either to completely hide the underlying federated services or to provide clients with services information. In both cases, the clearinghouse solution presents a higher level interface (i.e. OGC CSW) which harmonizes multiple lower level services (e.g. OGC CSW, WMS and WCS, THREDDS, etc.), and handles all control and interaction with them. In the translucent case, client has the option to directly access the lower level services (e.g. to improve performances). In the GEOSS context, the solution has been experimented both as a stand-alone user application and as a service framework. The first scenario allows a user to download a multi-platform client software and query a federation of cataloguing systems, that he can customize at will. The second scenario support server-side deployment and can be flexibly adapted to several use-cases, such as intranet proxy, catalog broker, etc.

  10. Searching the databases: a quick look at Amazon and two other online catalogues.

    Science.gov (United States)

    Potts, Hilary

    2003-01-01

    The Amazon Online Catalogue was compared with the Library of Congress Catalogue and the British Library Catalogue, both also available online, by searching on both neutral (Gay, Lesbian, Homosexual) and pejorative (Perversion, Sex Crime) subject terms, and also by searches using Boolean logic in an attempt to identify Lesbian Fiction items and religion-based anti-gay material. Amazon was much more likely to be the first port of call for non-academic enquiries. Although excluding much material necessary for academic research, it carried more information about the individual books and less historical homophobic baggage in its terminology than the great national catalogues. Its back catalogue of second-hand books outnumbered those in print. Current attitudes may partially be gauged by the relative numbers of titles published under each heading--e.g., there may be an inverse relationship between concern about child sex abuse and homophobia, more noticeable in U.S. because of the activities of the religious right.

  11. CERES ERBE-like Monthly Regional Averages (ES-9) in HDF ( CER_ES9_Terra-FM1_Edition1-CV)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    The ERBE-like Monthly Regional Averages (ES-9) product contains a month of space and time averaged Clouds and the Earth's Radiant Energy System (CERES) data for a single scanner instrument. The ES-9 is also produced for combinations of scanner instruments. All instantaneous shortwave and longwave fluxes at the Top-of-the-Atmosphere (TOA) from the CERES ES-8 product for a month are sorted by 2.5-degree spatial regions, by day number, and by the local hour of observation. The mean of the instantaneous fluxes for a given region-day-hour bin is determined and recorded on the ES-9 along with other flux statistics and scene information. For each region, the daily average flux is estimated from an algorithm that uses the available hourly data, scene identification data, and diurnal models. This algorithm is 'like' the algorithm used for the Earth Radiation Budget Experiment (ERBE). The ES-9 also contains hourly average fluxes for the month and an overall monthly average for each region. These average fluxes are given for both clear-sky and total-sky scenes. The following CERES ES9 data sets are currently available: CER_ES9_FM1+FM2_Edition1 CER_ES9_PFM+FM1+FM2_Edition1 CER_ES9_PFM+FM1+FM2_Edition2 CER_ES9_PFM+FM1_Edition1 CER_ES9_PFM+FM2_Edition1 CER_ES9_PFM+FM1_Edition2 CER_ES9_PFM+FM2_Edition2 CER_ES9_TRMM-PFM_Edition1 CER_ES9_TRMM-PFM_Edition2 CER_ES9_Terra-FM1_Edition1 CER_ES9_Terra-FM2_Edition1 CER_ES9_FM1+FM2_Edition2 CER_ES9_Terra-FM1_Edition2 CER_ES9_Terra-FM2_Edition2 CER_ES9_Aqua-FM3_Edition1 CER_ES9_Aqua-FM4_Edition1 CER_ES9_FM1+FM2+FM3+FM4_Edition1 CER_ES9_Aqua-FM3_Edition2 CER_ES9_Aqua-FM4_Edition2 CER_ES9_FM1+FM3_Edition2 CER_ES9_FM1+FM4_Edition2 CER_ES9_Aqua-FM3_Edition1-CV CER_ES9_Aqua-FM4_Edition1-CV CER_ES9_Terra-FM1_Edition1-CV CER_ES9_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1998-01-01; Stop_Date=2006-09-30] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost

  12. Impact of cadmium on forage kale (Brassica oleracea var. viridis cv "Prover") after 3-,10- and 56-day exposure to a Cd-spiked field soil.

    Science.gov (United States)

    Bernard, Fabien; Dumez, Sylvain; Lemière, Sébastien; Platel, Anne; Nesslany, Fabrice; Deram, Annabelle; Vandenbulcke, Franck; Cuny, Damien

    2018-03-15

    Cadmium (Cd) is a highly toxic element for living organisms and is widespread in metal-contaminated soils. As organisms which can grow up on these polluted areas, plants have some protection mechanisms against Cd issues. Among the plant kingdom, the Brassicaceae family includes species which are known to be able to tolerate and accumulate Cd in their tissues. In this study, Brassica oleracea var. viridis cv "Prover" was exposed to a range of artificially Cd-contaminated soils (from 2.5 up to 20 mg kg -1 ) during 3, 10, and 56 days and the effects on life traits, photosynthesis activity, antioxidant enzymatic activities were studied. Metal accumulation was quantified, as well as DNA damage, by means of the comet assay and immunodetection of 8-OHdG levels. Globally, B. oleracea was relatively tolerant to those Cd exposures. However, comet assay and detection of 8-OHdG revealed some DNA damage but which are not significant. According to metal accumulation analysis, B. oleracea var. viridis cv Prover could be a good candidate for alternative growing in contaminated areas.

  13. INDXENDF, Preparation of Visual Catalogue of ENDF Format Data

    International Nuclear Information System (INIS)

    Silva, Orion de O.; Paviotti Corcuera, R.; De Moraes Cunha, M.; Ferreira, P.A.

    1996-01-01

    1 - Description of program or function: This program is a video catalogue for libraries in the ENDF-4, ENDF-5 or ENDF-6 format (Evaluated Nuclear Data File) which can be run on an IBM-PC or compatible computer. This user friendly catalogue is of interest to nuclear and reactor physics researchers. The input is the filename of ENDF data and the two output files contain: i. the list of materials with corresponding laboratory, author and date of evaluation; ii. information about the MF and MT numbers for each material. The program is written in the C language whose capability of providing windows and 'interrupts' along with speed and portability, has been greatly exploited. The system allows output of options (i) and (ii) either on screen, printer or hard disk. 2 - Method of solution: The source code of about 3000 lines was written in C. The routines for windowing were based on the following works: Hummel (1988), Stevens (1989), Lafore (1987), Borland International (1988a, 1988b) and Schildt (1988, 1989). 3 - Restrictions on the complexity of the problem: The executable program occupies about 52 Kb of memory. The extra hard disk space needed depends upon the size of the ENDF/B data file to be processed (e.g. the Activation file contains about 1.3 M-bytes, the General Purpose ENDF/B-VI has four parts, each containing about 12 M-bytes). To run the program the 'datafile' and the executable code '.EXE' file should be on the hard-drive. The program may be run on any IBM/PC or compatible with at least 640 Kb RAM

  14. A randomized study of the immunogenicity and safety of Japanese encephalitis chimeric virus vaccine (JE-CV) in comparison with SA14-14-2 vaccine in children in the Republic of Korea.

    Science.gov (United States)

    Kim, Dong Soo; Houillon, Guy; Jang, Gwang Cheon; Cha, Sung-Ho; Choi, Soo-Han; Lee, Jin; Kim, Hwang Min; Kim, Ji Hong; Kang, Jin Han; Kim, Jong-Hyun; Kim, Ki Hwan; Kim, Hee Soo; Bang, Joon; Naimi, Zulaikha; Bosch-Castells, Valérie; Boaz, Mark; Bouckenooghe, Alain

    2014-01-01

    A new live attenuated Japanese encephalitis chimeric virus vaccine (JE-CV) has been developed based on innovative technology to give protection against JE with an improved immunogenicity and safety profile. In this phase 3, observer-blind study, 274 children aged 12-24 months were randomized 1:1 to receive one dose of JE-CV (Group JE-CV) or the SA14-14-2 vaccine currently used to vaccinate against JE in the Republic of Korea (Group SA14-14-2). JE neutralizing antibody titers were assessed using PRNT50 before and 28 days after vaccination. The primary endpoint of non-inferiority of seroconversion rates on D28 was demonstrated in the Per Protocol analysis set as the difference between Group JE-CV and Group SA14-14-2 was 0.9 percentage points (95% confidence interval [CI]: -2.35; 4.68), which was above the required -10%. Seroconversion and seroprotection rates 28 days after administration of a single vaccine dose were 100% in Group JE-CV and 99.1% in Group SA14-14-2; all children except one (Group SA14-14-2) were seroprotected. Geometric mean titers (GMTs) increased in both groups from D0 to D28; GM of titer ratios were slightly higher in Group JE-CV (182 [95% CI: 131; 251]) than Group SA14-14-2 (116 [95% CI: 85.5, 157]). A single dose of JE-CV was well tolerated and no safety concerns were identified. In conclusion, a single dose of JE-CV or SA14-14-2 vaccine elicited a comparable immune response with a good safety profile. Results obtained in healthy Korean children aged 12-24 months vaccinated with JE-CV are consistent with those obtained in previous studies conducted with JE-CV in toddlers.

  15. INTERSTOCK EFFECT ON THE GROWTH OF MANDARIN CV BATU 55, TANGERINE CV PONTIANAK AND LIME CV NIMAS PROPAGATED BY GRAFTING

    Directory of Open Access Journals (Sweden)

    Sugiyatno A.

    2017-10-01

    Full Text Available Japansche citroen (JC rootstock is still the main choice for producing citrus seeds for its high availability and compatibility. Other rootstocks have been used in the production, yet they produce unsatisfying results. Based on the theory, there is an alternative to use rootstock as interstock in order to stimulate the growth of scion. The objective of this reseach is to understand the effect of interstock on the growth of Mandarin cv. Batu 55, Tangerine cv. Pontianak and Lime cv. Nimas. This research was conducted in the screen house of Tlekung Experimental Field of Indonesian Citrus and Subtropical Fruits Research Institute (ICSFRI in Batu-East Java, located on 950 m asl, from January to April 2016. This research was arranged in a CRD design with 4 replications and 24 interstock-scion combination treatments. The interstocks used in this study were Carizzo citrange, Citrumello, Poncirus trifoliata, Volkameriana, Rough lemon, Troyer citrange, Kanci and control (JC combined with 3 scions namely Mandarin cv. Batu 55, Tangerine cv. Pontianak and Lime cv. Nimas propagated by grafting. The result showed the percentage of successful grafting ranged between 37.5% to 100%, while the percentage of the shoot formed on grafted plants was 75%-100%. The use of Poncirus trifoliata as interstock has stimulated fastest bud break on Tangerine cv. Pontianak in just 24.75 days while the Troyer citrange has stimulated better shoot growth in Lime cv. Nimas, resulted to the highest shoot around 52.20 cm which was significantly different from other treatments. Meanwhile, Carizzo citrange has been found to have some influences to the plant diameter and the number of leave of Lime cv. Nimas but showed insignificant effect on the growth of its own diameter. The use of interstock showed that it can be used to promote the growth of scion which usually has slow growth when it is directly grafted on the rootstock.

  16. NASA space geodesy program: Catalogue of site information

    Science.gov (United States)

    Bryant, M. A.; Noll, C. E.

    1993-01-01

    This is the first edition of the NASA Space Geodesy Program: Catalogue of Site Information. This catalogue supersedes all previous versions of the Crustal Dynamics Project: Catalogue of Site Information, last published in May 1989. This document is prepared under the direction of the Space Geodesy and Altimetry Projects Office (SGAPO), Code 920.1, Goddard Space Flight Center. SGAPO has assumed the responsibilities of the Crustal Dynamics Project, which officially ended December 31, 1991. The catalog contains information on all NASA supported sites as well as sites from cooperating international partners. This catalog is designed to provde descriptions and occupation histories of high-accuracy geodetic measuring sites employing space-related techniques. The emphasis of the catalog has been in the past, and continues to be with this edition, station information for facilities and remote locations utilizing the Satellite Laser Ranging (SLR), Lunar Laser Ranging (LLR), and Very Long Baseline Interferometry (VLBI) techniques. With the proliferation of high-quality Global Positioning System (GPS) receivers and Doppler Orbitography and Radiopositioning Integrated by Satellite (DORIS) transponders, many co-located at established SLR and VLBI observatories, the requirement for accurate station and localized survey information for an ever broadening base of scientists and engineers has been recognized. It is our objective to provide accurate station information to scientific groups interested in these facilities.

  17. Improvement Of Search Process In Electronic Catalogues

    Directory of Open Access Journals (Sweden)

    Titas Savickas

    2014-05-01

    Full Text Available The paper presents investigation on search in electronic catalogues. The chosen problem domain is the search system in the electronic catalogue of Lithuanian Academic Libraries. The catalogue uses ALEPH system with MARC21 bibliographic format. The article presents analysis of problems pertaining to the current search engine and user expectations related to the search system of the electronic catalogue of academic libraries. Subsequent to analysis, the research paper presents the architecture for a semantic search system in the electronic catalogue that uses search process designed to improve search results for users.

  18. Enhancement of electrochemical performance of LiNi_1_/_3Co_1_/_3Mn_1_/_3O_2 by surface modification with MnO_2

    International Nuclear Information System (INIS)

    Guo, Xin; Cong, Li-Na; Zhao, Qin; Tai, Ling-Hua; Wu, Xing-Long; Zhang, Jing-Ping; Wang, Rong-Shun; Xie, Hai-Ming; Sun, Li-Qun

    2015-01-01

    LiNi_1_/_3Co_1_/_3Mn_1_/_3O_2 is successfully coated with MnO_2 by a chemical deposition method. The X-ray diffraction (XRD), scanning electron microscope (SEM) and high resolution transmission electron microscope (HRTEM) results demonstrate that MnO_2 forms a thin layer on the surface of LiNi_1_/_3Co_1_/_3Mn_1_/_3O_2 without destroying the crystal structure of the core material. Compared with pristine LiNi_1_/_3Co_1_/_3Mn_1_/_3O_2, the MnO_2-coated sample shows enhanced electrochemical performance especially the rate capability. Even at a current density of 750 mA g"−"1, the discharge capacity of MnO_2-coated LiNi_1_/_3Co_1_/_3Mn_1_/_3O_2 is 155.15 mAh g"−"1, while that of the pristine electrode is only 132.84 mAh g"−"1 in the range of 2.5–4.5 V. The cyclic voltammetry (CV) and X-ray photoelectron spectroscopy (XPS) curves show that the MnO_2 coating layer reacts with Li"+ during cycling, which is responsible for the higher discharge capacity of MnO_2-coated LiNi_1_/_3Co_1_/_3Mn_1_/_3O_2. Electrochemical impedance spectroscopy (EIS) results confirmed that the MnO_2 coating layer plays an important role in reducing the charge transfer resistance on the electrolyte–electrode interfaces. - Highlights: • MnO_2 coated LiNi_1_/_3Co_1_/_3Mn_1_/_3O_2 cathode material is synthesized for the first time. • MnO_2 offers available sites for insertion of extracted lithium. • The preserved surface and crystal structures results in the improved kinetics.

  19. Galactic Bulge Giants: Probing Stellar and Galactic Evolution. 1. Catalogue of Spitzer IRAC and MIPS Sources (PREPRINT)

    Science.gov (United States)

    2010-12-29

    1997), the 2 Micron All Sky Survey ( 2MASS ; Skrutskie et al. 2006), the Midcourse Space Experiment (MSX) catalogue, and the Infra- Red Astronomical...made for these sources with a search radius of 3.′′0 with DENIS and 2MASS , and 30.′′0 for identification with an MSX or IRAS counterpart. The... 2MASS and DENIS counterpart (depending on the field, between 3.1% and 6.7% of the sources), or (ii) a DENIS and 2MASS counterpart at a distance

  20. WFCatalog: A catalogue for seismological waveform data

    Science.gov (United States)

    Trani, Luca; Koymans, Mathijs; Atkinson, Malcolm; Sleeman, Reinoud; Filgueira, Rosa

    2017-09-01

    This paper reports advances in seismic waveform description and discovery leading to a new seismological service and presents the key steps in its design, implementation and adoption. This service, named WFCatalog, which stands for waveform catalogue, accommodates features of seismological waveform data. Therefore, it meets the need for seismologists to be able to select waveform data based on seismic waveform features as well as sensor geolocations and temporal specifications. We describe the collaborative design methods and the technical solution showing the central role of seismic feature catalogues in framing the technical and operational delivery of the new service. Also, we provide an overview of the complex environment wherein this endeavour is scoped and the related challenges discussed. As multi-disciplinary, multi-organisational and global collaboration is necessary to address today's challenges, canonical representations can provide a focus for collaboration and conceptual tools for agreeing directions. Such collaborations can be fostered and formalised by rallying intellectual effort into the design of novel scientific catalogues and the services that support them. This work offers an example of the benefits generated by involving cross-disciplinary skills (e.g. data and domain expertise) from the early stages of design, and by sustaining the engagement with the target community throughout the delivery and deployment process.

  1. Catalogue of European earthquakes with intensities higher than 4

    International Nuclear Information System (INIS)

    Van Gils, J.M.; Leydecker, G.

    1991-01-01

    The catalogue of European earthquakes with intensities higher than 4 contains some 20 000 seismic events that happened in member countries of the European Communities, Switzerland and Austria. It was prepared on the basis of already existing national catalogues and includes historical data as well as present-day data. All historical data are harmonized as far as possible to the same intensity scale (MSK-scale) to make them suitable for computerization. Present-day data include instrumental and macroseismic data. Instrumental data are expressed in terms of magnitude (Richter scale) while macroseismic data are given in intensities. Compilation of seismic data can provide a basis for statistically supported studies of site selection procedures and the qualitative assessment of seismic risks. Three groups of seismic maps illustrate the content of the catalogue for different time periods and different intensities

  2. ALS mutant SOD1 interacts with G3BP1 and affects stress granule dynamics.

    Science.gov (United States)

    Gal, Jozsef; Kuang, Lisha; Barnett, Kelly R; Zhu, Brian Z; Shissler, Susannah C; Korotkov, Konstantin V; Hayward, Lawrence J; Kasarskis, Edward J; Zhu, Haining

    2016-10-01

    Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. Mutations in Cu/Zn superoxide dismutase (SOD1) are responsible for approximately 20 % of the familial ALS cases. ALS-causing SOD1 mutants display a gain-of-toxicity phenotype, but the nature of this toxicity is still not fully understood. The Ras GTPase-activating protein-binding protein G3BP1 plays a critical role in stress granule dynamics. Alterations in the dynamics of stress granules have been reported in several other forms of ALS unrelated to SOD1. To our surprise, the mutant G93A SOD1 transgenic mice exhibited pathological cytoplasmic inclusions that co-localized with G3BP1-positive granules in spinal cord motor neurons. The co-localization was also observed in fibroblast cells derived from familial ALS patient carrying SOD1 mutation L144F. Mutant SOD1, unlike wild-type SOD1, interacted with G3BP1 in an RNA-independent manner. Moreover, the interaction is specific for G3BP1 since mutant SOD1 showed little interaction with four other RNA-binding proteins implicated in ALS. The RNA-binding RRM domain of G3BP1 and two particular phenylalanine residues (F380 and F382) are critical for this interaction. Mutant SOD1 delayed the formation of G3BP1- and TIA1-positive stress granules in response to hyperosmolar shock and arsenite treatment in N2A cells. In summary, the aberrant mutant SOD1-G3BP1 interaction affects stress granule dynamics, suggesting a potential link between pathogenic SOD1 mutations and RNA metabolism alterations in ALS.

  3. Technology Catalogue

    International Nuclear Information System (INIS)

    1994-02-01

    The Department of Energy's Office of Environmental Restoration and Waste Management (EM) is responsible for remediating its contaminated sites and managing its waste inventory in a safe and efficient manner. EM's Office of Technology Development (OTD) supports applied research and demonstration efforts to develop and transfer innovative, cost-effective technologies to its site clean-up and waste management programs within EM's Office of Environmental Restoration and Office of Waste Management. The purpose of the Technology Catalogue is to provide performance data on OTD-developed technologies to scientists and engineers assessing and recommending technical solutions within the Department's clean-up and waste management programs, as well as to industry, other federal and state agencies, and the academic community. OTD's applied research and demonstration activities are conducted in programs referred to as Integrated Demonstrations (IDs) and Integrated Programs (IPs). The IDs test and evaluate.systems, consisting of coupled technologies, at specific sites to address generic problems, such as the sensing, treatment, and disposal of buried waste containers. The IPs support applied research activities in specific applications areas, such as in situ remediation, efficient separations processes, and site characterization. The Technology Catalogue is a means for communicating the status. of the development of these innovative technologies. The FY93 Technology Catalogue features technologies successfully demonstrated in the field through IDs and sufficiently mature to be used in the near-term. Technologies from the following IDs are featured in the FY93 Technology Catalogue: Buried Waste ID (Idaho National Engineering Laboratory, Idaho); Mixed Waste Landfill ID (Sandia National Laboratories, New Mexico); Underground Storage Tank ID (Hanford, Washington); Volatile organic compound (VOC) Arid ID (Richland, Washington); and VOC Non-Arid ID (Savannah River Site, South Carolina)

  4. On compact galaxies in the UGC catalogue

    International Nuclear Information System (INIS)

    Kogoshvili, N.G.

    1980-01-01

    A problem of separation of compact galaxies in the UGC Catalogue is considered. Value of surface brightness equal to or less than 21sup(m) was used as compactness criterion from a square second of arc. 96 galaxies, which are brighter than 14sup(m)5 satisfy this criterion. Among compact galaxies discovered in the UGC Catalogue 7% are the Zwicky galaxies, 15% belong to the Markarian galaxies and 27% of galaxies are part of a galaxy list with high surface brightness. Considerable divergence in estimates of total share of compact galaxies in the B.A. Worontsov-Veljaminov Morphological Catalogue of Galaxies (MCG) and the UGC Catalogue is noted. This divergence results from systematical underestimation of visible sizes of compact galaxies in the MCG Catalogue as compared with the UGC Catalogue [ru

  5. Clay club catalogue of characteristics of argillaceous rocks

    International Nuclear Information System (INIS)

    2005-01-01

    The OECD/NEA Working Group on the Characterisation, the Understanding and the Performance of Argillaceous Rocks as Repository Host Formations, namely the Clay Club, examines the various argillaceous rocks that are being considered for the deep geological disposal of radioactive waste, i.e. from plastic, soft, poorly indurated clays to brittle, hard mud-stones or shales. The Clay Club considered it necessary and timely to provide a catalogue to gather in a structured way the key geo-scientific characteristics of the various argillaceous formations that are - or were - studied in NEA member countries with regard to radioactive waste disposal. The present catalogue represents the outcomes of this Clay Club initiative. (author)

  6. Nebula observations. Catalogues and archive of photoplates

    Science.gov (United States)

    Shlyapnikov, A. A.; Smirnova, M. A.; Elizarova, N. V.

    2017-12-01

    A process of data systematization based on "Academician G.A. Shajn's Plan" for studying the Galaxy structure related to nebula observations is considered. The creation of digital versions of catalogues of observations and publications is described, as well as their presentation in HTML, VOTable and AJS formats and basic principles of work in the interactive application of International Virtual Observatory the Aladin Sky Atlas.

  7. Epigenetic regulation of HIV-1 latency: focus on polycomb group (PcG) proteins.

    Science.gov (United States)

    Khan, Sheraz; Iqbal, Mazhar; Tariq, Muhammad; Baig, Shahid M; Abbas, Wasim

    2018-01-01

    HIV-1 latency allows the virus to persist until reactivation, in a transcriptionally silent form in its cellular reservoirs despite the presence of effective cART. Such viral persistence represents a major barrier to HIV eradication since treatment interruption leads to rebound plasma viremia. Polycomb group (PcG) proteins have recently got a considerable attention in regulating HIV-1 post-integration latency as they are involved in the repression of proviral gene expression through the methylation of histones. This epigenetic regulation plays an important role in the establishment and maintenance of HIV-1 latency. In fact, PcG proteins act in complexes and modulate the epigenetic signatures of integrated HIV-1 promoter. Key role played by PcG proteins in the molecular control of HIV-1 latency has led to hypothesize that PcG proteins may represent a valuable target for future HIV-1 therapy in purging HIV-1 reservoirs. In this regard, various small molecules have been synthesized or explored to specifically block the epigenetic activity of PcG. In this review, we will highlight the possible therapeutic approaches to achieve either a functional or sterilizing cure of HIV-1 infection with special focus on histone methylation by PcG proteins together with current and novel pharmacological approaches to reactivate HIV-1 from latency that could ultimately lead towards a better clearance of viral latent reservoirs.

  8. Fox grape cv. Bordô (Vitis labrusca L.) and grapevine cv. Chardonnay (Vitis vinifera L.) cultivated in vitro under different carbohydrates, amino acids and 6-Benzylaminopurine levels

    OpenAIRE

    Carvalho, Dayse Cristina de; Silva, André Luís Lopes da; Schuck, Mariane Ruzza; Purcino, Marivel; Tanno, Guilherme Nakao; Biasi, Luiz Antonio

    2013-01-01

    The aim of this work was to study the influence of sucrose and glucose, amino acids and BAP (6-Benzylaminopurine) levels on in vitro shoot regeneration of fox grape cv. Bordô and grapevine cv. Chardonnay. The nodal segments from micropropagated material were used as explants and half-strength MS medium as the basal medium. Sucrose and glucose at 15, 30 and 45 g.L-1 were tested as a carbon source and the supplementation of adenine, asparagine, alanine, glycine, cysteine, glutamine, arginine wa...

  9. Elimination of browning exudate and in vitro development of shoots in Pistacia vera L. cv. mateur and Pistacia atlantica Desf. Culture

    Directory of Open Access Journals (Sweden)

    M. I. Trujillo

    2014-01-01

    Full Text Available We report diminution and/or elimination of browning exudate followed by in vitro establishment of in Pistacia vera cv. mateur and Pistacia atlantica explants. Soaking P. vera cv. mateur explants prior to culture in L-cysteine HCl for 15 min (100 µM inhibits blackening of the modified Murashige and Skoog medium - MS + 400 mg/l NH4NO3 - and of the explants; while shoot formation was increased. The browning in P. vera cv. mateur and P. atlantica explants dissolved when modified MS and Quoirin and Lepoivre - QL.4 - media were supplemented with activated charcoal (from 1 to 3 g l-1 and with 4 and 8 days of darkness. These treatments were enough to eliminate browning from the explants and to improve the shoots elongation, but symptoms of chlorosis were detected. On the other hand, AgNO3 (from 15 to 40 µ1V1 showed a very strong antibrowning effect on the medium and explants of P. atlantica. Thus shoot organogenesis was best achieved and the developing sturdy shoots had large and green leaves.

  10. NREL Information Resources Catalogue 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-04-03

    This is the sixth annual catalogue listing documents produced by NREL during the last fiscal year. Each year the catalogue is mailed to state energy offices, DOE support offices, and to anyone looking to find out more information about NREL's activities and publications.

  11. Regulated production and anti-HIV type 1 activities of cytidine deaminases APOBEC3B, 3F, and 3G.

    Science.gov (United States)

    Rose, Kristine M; Marin, Mariana; Kozak, Susan L; Kabat, David

    2005-07-01

    APOBEC3G and 3F (A3G and A3F) cytidine deaminases incorporate into retroviral cores where they lethally hypermutate nascent DNA reverse transcripts. As substantiated here, the viral infectivity factor (Vif) encoded by human immunodeficiency virus type-1 (HIV-1) binds A3G and A3F and induces their degradation, thereby precluding their incorporation into viral progeny. Previous evidence suggested that A3G is expressed in H9 and other nonpermissive cells that contain this antiviral defense but not in several permissive cells, and that overexpression of A3G or A3F makes permissive cells nonpermissive. Using a broader panel of cell lines, we confirmed a correlation between A3G and cellular abilities to inactivate HIV-1(Deltavif). However, there was a quantitative discrepancy because several cells with weak antiviral activities had similar amounts of wild-type A3G mRNA and protein compared to H9 cells. Antiviral activity of H9 cells was also attenuated in some conditions. These quantitative discrepancies could not be explained by the presence of A3F or other A3G paralogs in some of the cell lines. Thus, A3A, A3B, and A3C had weak but significant anti-HIV-1 activities and did not dominantly interfere with A3G or A3F antiviral functions. Control of A3G synthesis by the protein kinase C/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathway was also similar in permissive and nonpermissive cells. A3G in highly permissive cells is degraded by Vif, suggesting that it is not in a sequestered site, and is specifically incorporated in low amounts into HIV-1(Deltavif). Although A3G and/or A3F inactivate HIV-1(Deltavif) and are neutralized by Vif, the antiviral properties of cell lines are also influenced by other cellular and viral factors.

  12. Extending the ISC-GEM Global Earthquake Instrumental Catalogue

    Science.gov (United States)

    Di Giacomo, Domenico; Engdhal, Bob; Storchak, Dmitry; Villaseñor, Antonio; Harris, James

    2015-04-01

    After a 27-month project funded by the GEM Foundation (www.globalquakemodel.org), in January 2013 we released the ISC-GEM Global Instrumental Earthquake Catalogue (1900 2009) (www.isc.ac.uk/iscgem/index.php) as a special product to use for seismic hazard studies. The new catalogue was necessary as improved seismic hazard studies necessitate that earthquake catalogues are homogeneous (to the largest extent possible) over time in their fundamental parameters, such as location and magnitude. Due to time and resource limitation, the ISC-GEM catalogue (1900-2009) included earthquakes selected according to the following time-variable cut-off magnitudes: Ms=7.5 for earthquakes occurring before 1918; Ms=6.25 between 1918 and 1963; and Ms=5.5 from 1964 onwards. Because of the importance of having a reliable seismic input for seismic hazard studies, funding from GEM and two commercial companies in the US and UK allowed us to start working on the extension of the ISC-GEM catalogue both for earthquakes that occurred beyond 2009 and for earthquakes listed in the International Seismological Summary (ISS) which fell below the cut-off magnitude of 6.25. This extension is part of a four-year program that aims at including in the ISC-GEM catalogue large global earthquakes that occurred before the beginning of the ISC Bulletin in 1964. In this contribution we present the updated ISC GEM catalogue, which will include over 1000 more earthquakes that occurred in 2010 2011 and several hundreds more between 1950 and 1959. The catalogue extension between 1935 and 1949 is currently underway. The extension of the ISC-GEM catalogue will also be helpful for regional cross border seismic hazard studies as the ISC-GEM catalogue should be used as basis for cross-checking the consistency in location and magnitude of those earthquakes listed both in the ISC GEM global catalogue and regional catalogues.

  13. Assembly of the Lactuca sativa, L. cv. Tizian draft genome sequence reveals differences within major resistance complex 1 as compared to the cv. Salinas reference genome.

    Science.gov (United States)

    Verwaaijen, Bart; Wibberg, Daniel; Nelkner, Johanna; Gordin, Miriam; Rupp, Oliver; Winkler, Anika; Bremges, Andreas; Blom, Jochen; Grosch, Rita; Pühler, Alfred; Schlüter, Andreas

    2018-02-10

    Lettuce (Lactuca sativa, L.) is an important annual plant of the family Asteraceae (Compositae). The commercial lettuce cultivar Tizian has been used in various scientific studies investigating the interaction of the plant with phytopathogens or biological control agents. Here, we present the de novo draft genome sequencing and gene prediction for this specific cultivar derived from transcriptome sequence data. The assembled scaffolds amount to a size of 2.22 Gb. Based on RNAseq data, 31,112 transcript isoforms were identified. Functional predictions for these transcripts were determined within the GenDBE annotation platform. Comparison with the cv. Salinas reference genome revealed a high degree of sequence similarity on genome and transcriptome levels, with an average amino acid identity of 99%. Furthermore, it was observed that two large regions are either missing or are highly divergent within the cv. Tizian genome compared to cv. Salinas. One of these regions covers the major resistance complex 1 region of cv. Salinas. The cv. Tizian draft genome sequence provides a valuable resource for future functional and transcriptome analyses focused on this lettuce cultivar. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Retendering of ST-CV maintenance contract

    CERN Document Server

    Battistin, M

    2003-01-01

    During the next three years, the ST/CV group will be deeply involved in the installation works for the LHC project. During this period the need for maintenance activity will decrease. The minimum level will be reached during the “long shutdown” of the PS and SPS machines in 2005. The budget for the maintenance will decrease accordingly, thus the CV group had to review its maintenance strategy. The new contract, which started on January 1st 2003, has been defined to cope with these workload variations during the next years and to guarantee the minimum maintenance activity on the existing equipment. A lump-sum contract based on a win-win strategy has been discarded. The contractor no longer has to guarantee the performance of the CERN cooling and ventilation systems. A new price list strategy based on performance indicators and penalties has been chosen. The contractor now has to guarantee the performance of every maintenance operation demanded by CERN. This modification obliged the Operation section of the...

  15. Molecular Characterization of Echinococcus granulosus Cysts in North Indian Patients: Identification of G1, G3, G5 and G6 Genotypes

    Science.gov (United States)

    Sharma, Monika; Sehgal, Rakesh; Fomda, Bashir Ahmad; Malhotra, Anil; Malla, Nancy

    2013-01-01

    Background Cystic echinococcosis (CE) caused by the Echinococcus granulosus, is a major public health problem worldwide, including India. The different genotypes of E. granulosus responsible for human hydatidosis have been reported from endemic areas throughout the world. However, the genetic characterization of E. granulosus infecting the human population in India is lacking. The aim of study was to ascertain the genotype(s) of the parasite responsible for human hydatidosis in North India. Methodology/Principal Findings To study the transmission patterns of E. granulosus, genotypic analysis was performed on hydatid cysts obtained from 32 cystic echinococcosis (CE) patients residing in 7 different states of North India. Mitochondrial cytochrome c oxidase subunit1 (cox1) sequencing was done for molecular identification of the isolates. Most of the CE patients (30/32) were found to be infected with hydatid cyst of either G3 (53.1%) or G1 (40.62%) genotype and one each of G5 (cattle strain) and G6 (camel strain) genotype. Conclusions/Significance These findings demonstrate the zoonotic potential of G1 (sheep strain) and G3 (buffalo strain) genotypes of E. granulosus as these emerged as predominant genotypes infecting the humans in India. In addition to this, the present study reports the first human CE case infected with G5 genotype (cattle strain) in an Asian country and presence of G6 genotype (camel strain) in India. The results may have important implications in the planning of control strategies for human hydatidosis. PMID:23785531

  16. Evidence Based Cataloguing: Moving Beyond the Rules

    Directory of Open Access Journals (Sweden)

    Kathy Carter

    2010-12-01

    Full Text Available Cataloguing is sometimes regarded as a rule-bound, production-based activity that offers little scope for professional judgement and decision-making. In reality, cataloguing involves challenging decisions that can have significant service and financial impacts. The current environment for cataloguing is a maelstrom of changing demands and competing visions for the future. With information-seekers turning en masse to Google and their behaviour receiving greater attention, library vendors are offering “discovery layer” products to replace traditional OPACs, and cataloguers are examining and debating a transformed version of their descriptive cataloguing rules (Resource Description and Access or RDA. In his “Perceptions of the future of cataloging: Is the sky really falling?” (2009, Ivey provides a good summary of this environment. At the same time, myriad new metadata formats and schema are being developed and applied for digital collections in libraries and other institutions. In today’s libraries, cataloguing is no longer limited to management of traditional AACR and MARC-based metadata for traditional library collections. And like their parent institutions, libraries cannot ignore growing pressures to demonstrate accountability and tangible value provided by their services. More than ever, research and an evidence based approach can help guide cataloguing decision-making.

  17. [Effects of electroacupuncture of "Guanyuan" (CV 4)-"Zhongji" (CV 3) on ovarian P450 arom and P450c 17alpha expression and relevant sex hormone levels in rats with polycystic ovary syndrome].

    Science.gov (United States)

    Sun, Jie; Zhao, Ji-meng; Ji, Rong; Liu, Hui-rong; Shi, Yin; Jin, Chun-lan

    2013-12-01

    To observe the effect of electroacupuncture (EA) on ovarian P 450 arom and P 450 c 17 alpha (aromatases) expression and related sex hormone levels in polycystic ovary syndrome (PCOS) rats. Thirty SD rats were randomly divided into normal control group, model group and EA group (10 rats/group). PCOS model was made by intragastric administration of letrozole at 1 mg/kg per day for consecutive 21 days. "Guanyuan" (CV 4) and "Zhongji" (CV 3) acupoints were stimulated 20 min by EA (2 mA, 2 Hz), once daily for consecutive 14 days. The damp ovarian weight was weighed and the pathological changes of the ovarian tissue were observed after H. E. staining. Ultrastructural changes of the ovarian tissue were observed by transmission electron microscope. Immunohistochemical staining was adopted to detect ovarian follicle granulosa cell P 450 arom and follicle membrane cell P 450 c 17 alpha expression. The contents of estradiol (E 2), estrone (E 1), androstenedione (ASD), testosterone (T), follicle-stimulating hormone (FSH) and luteinizing hormone (LH) in the ovarian tissue were measured by ELISA. Compared with the normal group, there was a significant increase in the damp weight of both left and right ovarian tissues in the model group (P ovarian weight was remarkably reduced (P ovarian tissue such as thickening of the superficial albugineous coat of the ovary, thinning of the granular cell layer, and disappearance of the intraovular oocytes and coronaradiata under light microscope, and mitochondrion swelling, fracture or disappearance of mitochondrial cristae, and enlargement of the endoplasmic reticulum, etc. after modeling were obviously improved in the EA group. In comparison to the control group, the expression of the follicle granulosa cell P450 arom was significantly down-regulated and that of follicle membrane cell P 450 c 17 alpha was significantly upregulated in the model group (P ovarian tissues (P ovarian E 1 and E2 (P ovarian ASD, T and LH levels were notably

  18. Detoxification of microcystin-LR in water by Portulaca oleracea cv.

    Science.gov (United States)

    Isobe, Takatoshi; Okuhata, Hiroshi; Miyasaka, Hitoshi; Jeon, Bong-Seok; Park, Ho-Dong

    2014-03-01

    Microcystin-LR (0.02 μg/ml) in the hydroculture medium of Portulaca oleracea cv., became below the detection level (<0.0001 μg/ml) by HPLC analysis after 7 days. The toxicity of microcystin estimated with protein phosphatase inhibition assay, however, remained at 37% of the initial level, indicating that microcystin-LR was transformed by P. oleracea cv. into unknown compound(s) of lower toxicity. Copyright © 2013 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  19. Reactivation of UV- and γ-irradiated herpes virus in UV- and X-irradiated CV-1 cells

    International Nuclear Information System (INIS)

    Takimoto, K.; Niwa, O.; Sugahara, T.

    1982-01-01

    Enhanced reactivation of UV- and γ-irradiated herpes virus was investigated by the plaque assay on CV-1 monkey kidney monolayer cells irradiated with UV light or X-rays. Both UV- and X-irradiated CV-1 cells showed enhancement of survival of UV-irradiated virus, while little or no enhancement was detected for γ-irradiated virus assayed on UV- or X-irradiated cells. The enhanced reactivation of UV-irradiated virus was greater when virus infection was delayed 24 or 48 h, than for infection immediately following the irradiation of cells. Thus the UV- or X-irradiated CV-1 cells are able to enhance the repair of UV damaged herpes virus DNA, but not of γ-ray damaged ones. (author)

  20. Catalogue of Geadephaga (Coleoptera: Adephaga of America, north of Mexico

    Directory of Open Access Journals (Sweden)

    Yves Bousquet

    2012-11-01

    Full Text Available All scientific names of Trachypachidae, Rhysodidae, and Carabidae (including cicindelines recorded from America north of Mexico are catalogued. Available species-group names are listed in their original combinations with the author(s, year of publication, page citation, type locality, location of the name-bearing type, and etymology for many patronymic names. In addition, the reference in which a given species-group name is first synonymized is recorded for invalid taxa. Genus-group names are listed with the author(s, year of publication, page citation, type species with way of fixation, and etymology for most. The reference in which a given genus-group name is first synonymized is recorded for many invalid taxa. Family-group names are listed with the author(s, year of publication, page citation, and type genus. The geographical distribution of all species-group taxa is briefly summarized and their state and province records are indicated.One new genus-group taxon, Randallius new subgenus (type species: Chlaenius purpuricollis Randall, 1838, one new replacement name, Pterostichus amadeus new name for Pterostichus vexatus Bousquet, 1985, and three changes in precedence, Ellipsoptera rubicunda (Harris, 1911 for Ellipsoptera marutha (Dow, 1911, Badister micans LeConte, 1844 for Badister ocularis Casey, 1920, and Agonum deplanatum Ménétriés, 1843 for Agonum fallianum (Leng, 1919, are proposed. Five new genus-group synonymies and 65 new species-group synonymies, one new species-group status, and 12 new combinations (see Appendix 5 are established.The work also includes a discussion of the notable private North American carabid collections, a synopsis of all extant world geadephagan tribes and subfamilies, a brief faunistic assessment of the fauna, a list of valid species-group taxa, a list of North American fossil Geadephaga (Appendix 1, a list of North American Geadephaga larvae described or illustrated (Appendix 2, a list of Geadephaga species

  1. Practical cataloguing AACR, RDA and MARC 21

    CERN Document Server

    Welsh, Anne

    2012-01-01

    Written at a time of transition in international cataloguing, this book provides cataloguers and students with a background in general cataloguing principles, the code (AACR2) and format (MARC 21) and the new standard (RDA). It provides library managers with an overview of the development of RDA in order to equip them to make the transition.

  2. Supersymmetric M3-branes and G2 manifolds

    International Nuclear Information System (INIS)

    Cvetic, M.; Gibbons, G.W.; Lue, H.; Pope, C.N.

    2002-01-01

    We obtain a generalisation of the original complete Ricci-flat metric of G 2 holonomy on (R 4 xS 3 to a family with a nontrivial parameter λ. For generic λ the solution is singular, but it is regular when λ={-1,0,+1}. The case λ=0 corresponds to the original G 2 metric, and λ={-1,1} are related to this by an S 3 automorphism of the SU(2) 3 isometry group that acts on the S 3 xS 3 principal orbits. We then construct explicit supersymmetric M3-brane solutions in D=11 supergravity, where the transverse space is a deformation of this class of G 2 metrics. These are solutions of a system of first-order differential equations coming from a superpotential. We also find M3-branes in the deformed backgrounds of new G 2 holonomy metrics that include one found by A. Brandhuber, J. Gomis, S. Gubser and S. Gukov, and show that they also are supersymmetric

  3. Supersymmetric M3-branes and G2 manifolds

    Science.gov (United States)

    Cvetič, M.; Gibbons, G. W.; Lü, H.; Pope, C. N.

    2002-01-01

    We obtain a generalisation of the original complete Ricci-flat metric of G2 holonomy on R4×S 3 to a family with a nontrivial parameter λ. For generic λ the solution is singular, but it is regular when λ={-1,0,+1}. The case λ=0 corresponds to the original G2 metric, and λ={-1,1} are related to this by an S3 automorphism of the SU(2) 3 isometry group that acts on the S3× S3 principal orbits. We then construct explicit supersymmetric M3-brane solutions in D=11 supergravity, where the transverse space is a deformation of this class of G2 metrics. These are solutions of a system of first-order differential equations coming from a superpotential. We also find M3-branes in the deformed backgrounds of new G2 holonomy metrics that include one found by A. Brandhuber, J. Gomis, S. Gubser and S. Gukov, and show that they also are supersymmetric.

  4. Molecular characterization of Echinococcus granulosus cysts in north Indian patients: identification of G1, G3, G5 and G6 genotypes.

    Directory of Open Access Journals (Sweden)

    Monika Sharma

    Full Text Available BACKGROUND: Cystic echinococcosis (CE caused by the Echinococcus granulosus, is a major public health problem worldwide, including India. The different genotypes of E. granulosus responsible for human hydatidosis have been reported from endemic areas throughout the world. However, the genetic characterization of E. granulosus infecting the human population in India is lacking. The aim of study was to ascertain the genotype(s of the parasite responsible for human hydatidosis in North India. METHODOLOGY/PRINCIPAL FINDINGS: To study the transmission patterns of E. granulosus, genotypic analysis was performed on hydatid cysts obtained from 32 cystic echinococcosis (CE patients residing in 7 different states of North India. Mitochondrial cytochrome c oxidase subunit1 (cox1 sequencing was done for molecular identification of the isolates. Most of the CE patients (30/32 were found to be infected with hydatid cyst of either G3 (53.1% or G1 (40.62% genotype and one each of G5 (cattle strain and G6 (camel strain genotype. CONCLUSIONS/SIGNIFICANCE: These findings demonstrate the zoonotic potential of G1 (sheep strain and G3 (buffalo strain genotypes of E. granulosus as these emerged as predominant genotypes infecting the humans in India. In addition to this, the present study reports the first human CE case infected with G5 genotype (cattle strain in an Asian country and presence of G6 genotype (camel strain in India. The results may have important implications in the planning of control strategies for human hydatidosis.

  5. Influência do 1-MCP na conservação pós-colheita de rosas cv. Vega Influence of 1-MCP on postharvest conservation of roses cv. Vega

    Directory of Open Access Journals (Sweden)

    Júlia De Pietro

    2010-10-01

    Full Text Available Objetivou-se, neste trabalho, estudar aspectos da fisiologia pós-colheita de rosas cortadas cv. Vega, tratadas com diferentes concentrações de 1-metilcicloropropeno (1-MCP. O experimento foi conduzido em delineamento inteiramente casualizado, em esquema fatorial composto por dois fatores: quatro tratamentos pós-colheita e quatro datas de avaliação (0; 4; 8; 12 dias. As flores foram submetidas aos seguintes tratamentos: 1 Água destilada (controle; 2 1-MCP (100 ppb; 3 1-MCP (250 ppb; 4 1-MCP (500 ppb. Foram realizadas as seguintes avaliações: massa fresca, cor, turgescência, curvatura, taxa respiratória, conteúdo relativo de água, conteúdo de carboidratos solúveis, de redutores e de antocianina. Ao contrário do tratamento controle, todas as concentrações de 1-MCP foram eficientes para retardar a senescência das flores, porém, a concentração de 1-MCP a 500 ppb destacou-se pela melhor manutenção da qualidade, além de prolongar a vida decorativa das hastes até 19 dias.The objective of this work was to study aspects of postharvest physiology of cut roses cv. Vega, treated with different concentrations of 1-metilcloropropene (1-MCP. The experiment was conducted in a complete randomized design composed of two factors: four postharvest treatments and four dates of evaluation (0; 4; 8; 12 days. The following treatments were used: 1 distilled water; 2 1-metilciclopropeno (1-MCP 100 ppb; 3 1-MCP 250 ppb; 4 1-MCP 500 ppb. The following evaluations were made: fresh weight, color, turgor, curvature, respiration rate, relative water content, content of soluble carbohydrates, reducing and anthocyanin. Unlike treatment with distilled water, all concentrations of 1-MCP were effective in delaying the senescence of flowers; however, the concentration of 1-MCP at 500 ppb was highlighted by better maintenance of quality and extended decorate life stem up to 19 days.

  6. Avaliação da cv. Merlot para elaboração de vinho tinto Evaluation of cv. Merlot to make red wine

    Directory of Open Access Journals (Sweden)

    Luiz Antenor Rizzon

    2003-12-01

    Full Text Available A uva Merlot é uma das responsáveis pelas características dos vinhos tintos de Saint Émillion, região de Bordeaux, França. Foi introduzida no Rio Grande do Sul através da Estação Agronômica de Porto Alegre. É, atualmente, uma das cultivares tinta de Vitis vinifera L. com maior volume de produção da Serra Gaúcha. É utilizada para a elaboração de vinho tinto para ser consumido jovem. O objetivo do presente trabalho foi avaliar o potencial enológico da cv. Merlot para a elaboração de vinho tinto fino. Para isso, realizaram-se estudos para caracterizar o cacho, o mosto e o vinho nas safras de 1987 a 1994, em Bento Gonçalves, RS. Os resultados evidenciaram que a cv. Merlot tem cacho com peso médio de 161,9g e baga esférica e pequena, pesando 1,61g. No mosto, o valor médio de açúcar é de 18,4ºBrix; o da acidez total, de 104meqL-1; e o do pH, de 3,21. O vinho se caracteriza por ter teores médios de 10,8% v/v de álcool; 70,3meqL-1 de acidez titulável; e pH de 3,49. Sob o aspecto sensorial, o vinho Merlot apresenta cor vermelho-violáceo com boa intensidade. Gustativamente distingue-se pela maciez, equilíbrio e fineza.Merlot is a traditional grape of the Saint Émillion wines, Bordeaux region - France. It was introduced into, the State of Rio Grande do Sul by the Estação Agronômica de Porto Alegre, Brazil. Today, of the red grape cultivars it shows the largest production in the Serra Gaúcha region. The purpose of this work was to evaluate the enological potential of Merlot grapes for red winemaking. To achieve this purpose, variables related to berry clusters, must and wine were measured between 1987 and 1994 vintages, from Merlot vineyards located in the municipality of Bento Gonçalves. The results showed that Merlot grapes have clusters of medium size (161.9g and small berries (1.61g. The must showed adequate sugar level (18.4ºBrix, high titratable acidity (104mqL-1 and medium pH 3.21. The wine Merlot had an

  7. Sustainable energy catalogue - for European decision-makers. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Gram, S.; Jacobsen, Soeren

    2006-10-15

    The Green paper - A European Strategy for Sustainable, Competitive and Secure Energy, 2006 states that Europe has a rising dependency on imported energy reserves, which are concentrated in a few countries. The Rising gas and oil prices along with demands on lower emissions of CO2 adds pressure on the need for a new energy future for Europe. EU has since 1990 planned to become world leader in the renewable energy field. Therefore the EU member states have agreed that by 2010 21% of the consumed electricity and 5,75% of the consumed gasoline and diesel should originate from renewable energy sources. If the EU countries are to reach their goals, a commitment on several levels to develop and install energy from sustainable energy sources is needed. The purpose of this catalogue is to offer planners and decision-makers in EU states an inspirational tool to be used during local or regional transition towards sustainable energy technologies. The catalogue can also be used by everyone else who needs an overview of the sustainable energy technologies and their current development level and future potential, among others educational use is relevant. The catalogue provides an introduction to the following technologies that are already or are estimated to become central to a development with renewable energy in EU: Technologies for wind energy, wave energy, geothermal energy, bioenergy, solar energy, hydropower and fuel cells. The catalogue also includes a section about energy systems, which also includes a part about technologies for efficient use of energy. The catalogue could have included a few other technologies as e.g. heating pumps, but due to the size of the catalogue a priority was necessary. The catalogue does not claim to give all answers or to be complete regarding all details about the individual technologies; even so it offers information, which cannot easily be looked up on the Internet. In the back of the catalogue, under 'References and links' there

  8. G3BP1, G3BP2 and CAPRIN1 are required for translation of interferon stimulated mRNAs and are targeted by a dengue virus non-coding RNA.

    Science.gov (United States)

    Bidet, Katell; Dadlani, Dhivya; Garcia-Blanco, Mariano A

    2014-07-01

    Viral RNA-host protein interactions are critical for replication of flaviviruses, a genus of positive-strand RNA viruses comprising major vector-borne human pathogens including dengue viruses (DENV). We examined three conserved host RNA-binding proteins (RBPs) G3BP1, G3BP2 and CAPRIN1 in dengue virus (DENV-2) infection and found them to be novel regulators of the interferon (IFN) response against DENV-2. The three RBPs were required for the accumulation of the protein products of several interferon stimulated genes (ISGs), and for efficient translation of PKR and IFITM2 mRNAs. This identifies G3BP1, G3BP2 and CAPRIN1 as novel regulators of the antiviral state. Their antiviral activity was antagonized by the abundant DENV-2 non-coding subgenomic flaviviral RNA (sfRNA), which bound to G3BP1, G3BP2 and CAPRIN1, inhibited their activity and lead to profound inhibition of ISG mRNA translation. This work describes a new and unexpected level of regulation for interferon stimulated gene expression and presents the first mechanism of action for an sfRNA as a molecular sponge of anti-viral effectors in human cells.

  9. BioCatalogue: a universal catalogue of web services for the life sciences.

    Science.gov (United States)

    Bhagat, Jiten; Tanoh, Franck; Nzuobontane, Eric; Laurent, Thomas; Orlowski, Jerzy; Roos, Marco; Wolstencroft, Katy; Aleksejevs, Sergejs; Stevens, Robert; Pettifer, Steve; Lopez, Rodrigo; Goble, Carole A

    2010-07-01

    The use of Web Services to enable programmatic access to on-line bioinformatics is becoming increasingly important in the Life Sciences. However, their number, distribution and the variable quality of their documentation can make their discovery and subsequent use difficult. A Web Services registry with information on available services will help to bring together service providers and their users. The BioCatalogue (http://www.biocatalogue.org/) provides a common interface for registering, browsing and annotating Web Services to the Life Science community. Services in the BioCatalogue can be described and searched in multiple ways based upon their technical types, bioinformatics categories, user tags, service providers or data inputs and outputs. They are also subject to constant monitoring, allowing the identification of service problems and changes and the filtering-out of unavailable or unreliable resources. The system is accessible via a human-readable 'Web 2.0'-style interface and a programmatic Web Service interface. The BioCatalogue follows a community approach in which all services can be registered, browsed and incrementally documented with annotations by any member of the scientific community.

  10. CV-Online tahab Londoni börsile / Annika Matson

    Index Scriptorium Estoniae

    Matson, Annika, 1976-

    2004-01-01

    Personaliotsinguga tegelev firma tahab tulevikus minna Londoni ja OMXi börsile. Diagramm: CV-Online Group loodab tänavu esmakordselt positiivse kulumieelse ärikasumi. Vt. samas: Üks CV-Online'i aktsionäridest on ka Google'i aktsionär; Väsinud ootamast esimest IPOt

  11. Analysis of the seismic catalogues for the Vrancea Region, Romania

    International Nuclear Information System (INIS)

    Romashkova, L.L.; Kossobokov, V.G.

    2005-11-01

    Vrancea (Romania) is a geographical region between Eastern and Southern Carpathian Mountains. The region is characterized by a rather high level of seismic activity mainly at intermediate (up to 200 km) depths. These intermediate-depth earthquakes occur between 45 deg-46 deg N and 26 deg-27 deg E. The shallow earthquakes are dispersed over a much broader territory. We performed the comparative analysis of earthquake catalogues available for Vrancea region aiming at the compilation of a data set, to be as complete and homogeneous as possible, which, hopefully, will be used for the prediction of strong and possibly moderate earthquakes in the region by means of M8 algorithm. The two catalogues under study are: 1) Global Hypocenter Data Base catalogue, NEIC (GHDB, 1989) and 2) local Vrancea seismic catalogue (Moldoveanu et al., 1995) and their updates. (author)

  12. Model Validation for Estimating the Leaf Stomatal Conductance in cv. Cabernet Sauvignon Grapevines Validación de un modelo para estimar la conductancia estomática de hojas en vides cv. Cabernet Sauvignon.

    Directory of Open Access Journals (Sweden)

    Francisco Jara-Rojas

    2009-03-01

    Full Text Available The coupled model of assimilation and stomatal conductance (A-g s was evaluated to estimate leaf stomatal conductance of a drip-irrigated vineyard (Vitis vinifera L. cv. Cabernet Sauvignon located in the Pencahue Valley (35º22’ S, 71°47’ W, 150 m.a.s.l., Maule Region, Chile, during the 2003-2004 and the 2004-2005 growing seasons. Additionally, a calibration of the three parameters mesophyll conductance (g m, maximum specific humidity (Dmax and coupled factor (f0 was applied on vines growing in 35 L pots. An infrared gas analyzer was used to calibrate and evaluate the A-g s which allowed simultaneous measuring of the leaf net CO2 assimilation (A and stomatal conductance (g s in 2 to 3 h intervals of time. The calibration indicated that the g m,, Dmax and f0 values were 1.15 mm s-1, 52.31 g kg-1 and 0.90, respectively. The validation in the drip-irrigated vineyard indicated that the A-g s model was able to estimate the leaf stomatal conductance with a root mean square error (RMSE of 0.05 mol m-2 s-1, model efficiency of 61% and agreement index of 90%. The sensitivity analysis indicated that the A-g s model is affected considerably by the g m, Dmax and f0 parameterization.Validación de un modelo para estimar la conductancia estomática de hojas en vides cv. Cabernet Sauvignon. El modelo acoplado de asimilación neta y conductancia estomática (A-g s fue evaluado para estimar la conductancia estomática de hojas (g s de un viñedo regado por goteo (Vitis vinifera L. cv. Cabernet Sauvignon ubicado en el Valle de Pencahue (35º22’ S; 71º47’ O; 150 m.s.n.m., Región del Maule, Chile, durante las temporadas 2003-2004 y 2004-2005. Además, se realizó una calibración de la conductancia del mesófilo (g m, valor máximo de humedad específica a saturación (Dmax y el factor acoplado (f0 en vides creciendo en maceteros de 35 L. Para calibrar y evaluar el modelo A-g s se utilizó un analizador infrarrojo de gases, el cual permitió medir simult

  13. Genetic variants in CHI3L1 influencing YKL-40 levels

    DEFF Research Database (Denmark)

    Kjaergaard, Alisa D; Johansen, Julia S; Nordestgaard, Børge G

    2013-01-01

    Despite its important role in many serious diseases, the genetic background for plasma YKL-40 has still not been systematically catalogued. Therefore, we aimed at identifying genetic variants in CHI3L1 influencing plasma YKL-40 levels in the general population.......Despite its important role in many serious diseases, the genetic background for plasma YKL-40 has still not been systematically catalogued. Therefore, we aimed at identifying genetic variants in CHI3L1 influencing plasma YKL-40 levels in the general population....

  14. Transport Infrastructure in the Process of Cataloguing Brownfields

    Science.gov (United States)

    Kramářová, Zuzana

    2017-10-01

    To begin with, the identification and follow-up revitalisation of brownfields raises a burning issue in territorial planning as well as in construction engineering. This phenomenon occurs not only in the Czech Republic and Europe, but also world-wide experts conduct its careful investigation. These issues may be divided into several areas. First, it is identifying and cataloguing single territorial localities; next, it means a complex process of locality revitalisation. As a matter of fact, legislative framework represents a separate area, which is actually highly specific in individual countries in accordance with the existing law, norms and regulations (it concerns mainly territorial planning and territory segmentation into appropriate administrative units). Legislative base of the Czech Republic was analysed in an article at WMCAUS in 2016. The solution of individual identification and following cataloguing of brownfields is worked out by Form of Regional Studies within the Legislation of the Czech Republic. Due to huge the scale of issues to be tackled, their content is only loosely defined in regard to Building Act and its implementing regulations, e.g. examining the layout of future construction in the area, locating architecturally or otherwise interesting objects, transport or technical infrastructure management, tourism, socially excluded localities etc. Legislative base does not exist, there is no common method for identifying and cataloguing brownfields. Therefore, individual catalogue lists are subject to customer’s requirements. All the same, the relevant information which the database contains may be always examined. One of them is part about transport infrastructure. The information may be divided into three subareas - information on transport accessibility of the locality, information on the actual infrastructure in the locality and information on the transport accessibility of human resources.

  15. Molecular cloning and expression of five glutathione S-transferase (GST) genes from Banana (Musa acuminata L. AAA group, cv. Cavendish).

    Science.gov (United States)

    Wang, Zhuo; Huang, Suzhen; Jia, Caihong; Liu, Juhua; Zhang, Jianbin; Xu, Biyu; Jin, Zhiqiang

    2013-09-01

    Three tau class MaGSTs responded to abiotic stress, MaGSTF1 and MaGSTL1 responded to signaling molecules, they may play an important role in the growth of banana plantlet. Glutathione S-transferases (GST) are multifunctional detoxification enzymes that participate in a variety of cellular processes, including stress responses. In this study, we report the molecular characteristics of five GST genes (MaGSTU1, MaGSTU2, MaGSTU3, MaGSTF1 and MaGSTL1) cloned from banana (Musa acuminate L. AAA group, cv. Cavendish) using a RACE-PCR-based strategy. The predicted molecular masses of these GSTs range from 23.4 to 27.7 kDa and their pIs are acidic. At the amino acid level, they share high sequence similarity with GSTs in the banana DH-Pahang (AA group) genome. Phylogenetic analysis showed that the deduced amino acid sequences of MaGSTs also have high similarity to GSTs of other plant species. Expression analysis by semi-quantitative RT-PCR revealed that these genes are differentially expressed in various tissues. In addition, their expression is regulated by various stress conditions, including exposure to signaling molecules, cold, salinity, drought and Fusarium oxysporum f specialis(f. Sp) cubense Tropical Race 4 (Foc TR4) infection. The expression of the tau class MaGSTs (MaGSTU1, MaGSTU2 and MaGSTU3) mainly responded to cold, salinity and drought while MaGSTF1 and MaGSTL1 expressions were upregulated by signaling molecules. Our findings suggest that MaGSTs play a key role in both development and abiotic stress responses.

  16. G3BP1, G3BP2 and CAPRIN1 are required for translation of interferon stimulated mRNAs and are targeted by a dengue virus non-coding RNA.

    Directory of Open Access Journals (Sweden)

    Katell Bidet

    2014-07-01

    Full Text Available Viral RNA-host protein interactions are critical for replication of flaviviruses, a genus of positive-strand RNA viruses comprising major vector-borne human pathogens including dengue viruses (DENV. We examined three conserved host RNA-binding proteins (RBPs G3BP1, G3BP2 and CAPRIN1 in dengue virus (DENV-2 infection and found them to be novel regulators of the interferon (IFN response against DENV-2. The three RBPs were required for the accumulation of the protein products of several interferon stimulated genes (ISGs, and for efficient translation of PKR and IFITM2 mRNAs. This identifies G3BP1, G3BP2 and CAPRIN1 as novel regulators of the antiviral state. Their antiviral activity was antagonized by the abundant DENV-2 non-coding subgenomic flaviviral RNA (sfRNA, which bound to G3BP1, G3BP2 and CAPRIN1, inhibited their activity and lead to profound inhibition of ISG mRNA translation. This work describes a new and unexpected level of regulation for interferon stimulated gene expression and presents the first mechanism of action for an sfRNA as a molecular sponge of anti-viral effectors in human cells.

  17. Automorphism group of nonabelian groups of order p{sup 3}

    Energy Technology Data Exchange (ETDEWEB)

    Sarmin, Nor Haniza [Department of Mathematical Sciences, Faculty of Science, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru (Malaysia); Barakat, Yasamin [Department of Mathematical Sciences, Faculty of Science, Universiti Teknologi Malaysia, 81310 UTM Johor Bahru, Malaysia and Islamic Azad University-Ahvaz Branch, Ahvaz (Iran, Islamic Republic of)

    2014-06-19

    Let G be a nonabelian group of order p{sup 3}, where p is a prime number. Then G is a two generated group that its commutator, centre and Frattini subgroup coincide and are of order p. Hence, the quotient group of G over its centre and also Frattini quotient group of G, both are of order p{sup 2}. However, the first mentioned quotient is isomorphic to the inner group of G, which is a normal subgroup of automorphism group of G. Whereas, Frattini quotient group of G is an abelian elementary group that can be considered as a vector space of dimension two over Z{sub p}, the field of integers modulo p. In this paper, we consider to apply these properties of G to characterize the automorphism group of G.

  18. Electroacupuncture stimulation at CV4 prevents ovariectomy-induced osteoporosis in rats via Wnt-β-catenin signaling.

    Science.gov (United States)

    Fan, Huailing; Ji, Feng; Lin, Ying; Zhang, Mulan; Qin, Wei; Zhou, Qi; Wu, Qiang

    2016-03-01

    The present study aimed to investigate the effect of electroacupuncture stimulation at CV4 (also termed Guanyuan) on femoral osteocalcin also termed bone gla protein (BGP), alkaline phosphatase (ALP), bone mineral density (BMD) and biomechanics, as well as the Wnt‑β‑catenin signaling pathway in rats with postmenopausal osteoporosis. Female Sprague‑Dawley rats (4.5‑months old) were randomly divided into sham, Ovx, CV4 and mock groups (n=10/group). With the exception of those in the sham group, the rats were ovariectomized to induce postmenopausal osteoporosis. The rats in the CV4 and mock groups were given electroacupuncture at CV4 and non‑acupoint, respectively. The rats in the Ovx model and sham groups underwent identical fixing procedures, but did not undergo electroacupuncture. Following treatment, hematoxylin and eosin staining was used to observe morphological changes in the left femoral trabecular bone, and a three‑point‑bending test was used to analyze femur biomechanics and determine the BMD. In addition, an enzyme‑linked immunosorbent assay was used to measure the serum levels of ALP/BGP and reverse transcription‑quantitative polymerase chain reaction was used detect the expression levels of Wnt3a, β‑catenin and Runx2. In the present study, it was demonstrated that electroacupuncture at CV4 significantly improved the osteoporotic morphological changes that occurred in the ovariectomized rats, increased serum ALP and BGP levels, enhanced the maximum and fracture loads, increased BMD (Pelectroacupuncture stimulation at CV4 affected bone formation and promoted bone metabolism in rats with postmenopausal osteoporosis, possibly by activating the Wnt‑β‑catenin signaling pathway.

  19. Plasminogen activator inhibitor-1 4G/5G polymorphism in infertile women with and without endometriosis.

    Science.gov (United States)

    Gonçalves-Filho, Rubens P; Brandes, Ariel; Christofolini, Denise M; Lerner, Tatiana G; Bianco, Bianca; Barbosa, Caio P

    2011-05-01

    To evaluate PAI-1 genotypes in a group of infertile women with or without endometriosis and control subjects. Case-control study. Human Reproduction Center of Medicina do ABC Faculty. One hundred and forty infertile women with endometriosis, 64 women with idiopathic infertility and 148 fertile women as control subjects. The PAI-1 4G/5G polymorphism was identified by restriction fragment length polymorphism-polymerase chain reaction. Genotype distribution and allele frequency of the 4G/5G polymorphism of the PAI-1 gene. The frequencies of genotypes 4G/4G, 4G/5G and 5G/5G of the PAI-1 gene in the infertile women with endometriosis were 38.6, 37.1 and 24.3%, respectively, and in the control group 24.3, 33.8 and 41.9%, respectively (p=0.003). When the infertile women with endometriosis were divided according to their endometriosis stage, genotypes 4G/4G, 4G/5G and 5G/5G were identified, respectively, in 36.7, 32.9 and 30.4% of the patients with minimal/mild endometriosis (p=0.102) and in 41.0, 42.6 and 16.4% of the patients with moderate/severe endometriosis (p=0.001); in the women with idiopathic infertility, these genotypes were found at a frequency of 29.7, 34.3 and 36%, respectively (p=0.637). The data suggest that, in Brazilian women, the PAI-1 4G/5G polymorphism may be associated with a risk of endometriosis-associated infertility. © 2011 The Authors Acta Obstetricia et Gynecologica Scandinavica© 2011 Nordic Federation of Societies of Obstetrics and Gynecology.

  20. Planck 2013 results. XXXII. The updated Planck catalogue of Sunyaev-Zeldovich sources

    Science.gov (United States)

    Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Armitage-Caplan, C.; Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Aussel, H.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Barrena, R.; Bartelmann, M.; Bartlett, J. G.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bikmaev, I.; Bobin, J.; Bock, J. J.; Böhringer, H.; Bonaldi, A.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Bridges, M.; Bucher, M.; Burenin, R.; Burigana, C.; Butler, R. C.; Cardoso, J.-F.; Carvalho, P.; Catalano, A.; Challinor, A.; Chamballu, A.; Chary, R.-R.; Chen, X.; Chiang, H. C.; Chiang, L.-Y.; Chon, G.; Christensen, P. R.; Churazov, E.; Church, S.; Clements, D. L.; Colombi, S.; Colombo, L. P. L.; Comis, B.; Couchot, F.; Coulais, A.; Crill, B. P.; Curto, A.; Cuttaia, F.; Da Silva, A.; Dahle, H.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Delouis, J.-M.; Démoclès, J.; Désert, F.-X.; Dickinson, C.; Diego, J. M.; Dolag, K.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Dupac, X.; Efstathiou, G.; Enßlin, T. A.; Eriksen, H. K.; Feroz, F.; Ferragamo, A.; Finelli, F.; Flores-Cacho, I.; Forni, O.; Frailis, M.; Franceschi, E.; Fromenteau, S.; Galeotta, S.; Ganga, K.; Génova-Santos, R. T.; Giard, M.; Giardino, G.; Gilfanov, M.; Giraud-Héraud, Y.; González-Nuevo, J.; Górski, K. M.; Grainge, K. J. B.; Gratton, S.; Gregorio, A.; Groeneboom, N., E.; Gruppuso, A.; Hansen, F. K.; Hanson, D.; Harrison, D.; Hempel, A.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huffenberger, K. M.; Hurier, G.; Hurley-Walker, N.; Jaffe, A. H.; Jaffe, T. R.; Jones, W. C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Khamitov, I.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Knox, L.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Laureijs, R. J.; Lawrence, C. R.; Leahy, J. P.; Leonardi, R.; León-Tavares, J.; Lesgourgues, J.; Li, C.; Liddle, A.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; MacTavish, C. J.; Maffei, B.; Maino, D.; Mandolesi, N.; Maris, M.; Marshall, D. J.; Martin, P. G.; Martínez-González, E.; Masi, S.; Massardi, M.; Matarrese, S.; Matthai, F.; Mazzotta, P.; Mei, S.; Meinhold, P. R.; Melchiorri, A.; Melin, J.-B.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mikkelsen, K.; Mitra, S.; Miville-Deschênes, M.-A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nastasi, A.; Nati, F.; Natoli, P.; Nesvadba, N. P. H.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Noviello, F.; Novikov, D.; Novikov, I.; O'Dwyer, I. J.; Olamaie, M.; Osborne, S.; Oxborrow, C. A.; Paci, F.; Pagano, L.; Pajot, F.; Paoletti, D.; Pasian, F.; Patanchon, G.; Pearson, T. J.; Perdereau, O.; Perotto, L.; Perrott, Y. C.; Perrotta, F.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Popa, L.; Poutanen, T.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Reach, W. T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Roudier, G.; Rowan-Robinson, M.; Rubiño-Martín, J. A.; Rumsey, C.; Rusholme, B.; Sandri, M.; Santos, D.; Saunders, R. D. E.; Savini, G.; Schammel, M. P.; Scott, D.; Seiffert, M. D.; Shellard, E. P. S.; Shimwell, T. W.; Spencer, L. D.; Starck, J.-L.; Stolyarov, V.; Stompor, R.; Streblyanska, A.; Sudiwala, R.; Sunyaev, R.; Sureau, F.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Tavagnacco, D.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tramonte, D.; Tristram, M.; Tucci, M.; Tuovinen, J.; Türler, M.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vibert, L.; Vielva, P.; Villa, F.; Vittorio, N.; Wade, L. A.; Wandelt, B. D.; White, M.; White, S. D. M.; Yvon, D.; Zacchei, A.; Zonca, A.

    2015-09-01

    We update the all-sky Planck catalogue of 1227 clusters and cluster candidates (PSZ1) published in March 2013, derived from detections of the Sunyaev-Zeldovich (SZ) effect using the first 15.5 months of Planck satellite observations. As an addendum, we deliver an updated version of the PSZ1 catalogue, reporting the further confirmation of 86 Planck-discovered clusters. In total, the PSZ1 now contains 947 confirmed clusters, of which 214 were confirmed as newly discovered clusters through follow-up observations undertaken by the Planck Collaboration. The updated PSZ1 contains redshifts for 913 systems, of which 736 (~ 80.6%) are spectroscopic, and associated mass estimates derived from the Yz mass proxy. We also provide a new SZ quality flag for the remaining 280 candidates. This flag was derived from a novel artificial neural-network classification of the SZ signal. Based on this assessment, the purity of the updated PSZ1 catalogue is estimated to be 94%. In this release, we provide the full updated catalogue and an additional readme file with further information on the Planck SZ detections. The catalogue is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/581/A14

  1. VizieR Online Data Catalog: A unified supernova catalogue (Lennarz+, 2012)

    Science.gov (United States)

    Lennarz, D.; Altmann, D.; Wiebusch, C.

    2011-11-01

    A supernova catalogue containing data for 5526 extragalactic supernovae that were discovered up to 2010 December 31. It combines several catalogues that are currently available online in a consistent and traceable way. During the comparison of the catalogues inconsistent entries were identified and resolved where possible. Remaining inconsistencies are marked transparently and can be easily identified. Thus it is possible to select a high-quality sample in a most simple way. Where available, redshift-based distance estimates to the supernovae were replaced by journal-refereed distances. (1 data file).

  2. The Plasminogen Activator Inhibitor 1 4G/5G Polymorphism and the Risk of Alzheimer's Disease.

    Science.gov (United States)

    Fekih-Mrissa, Najiba; Mansour, Malek; Sayeh, Aicha; Bedoui, Ines; Mrad, Meriem; Riahi, Anis; Mrissa, Ridha; Nsiri, Brahim

    2017-09-01

    The aim of this study was to determine whether plasminogen activator inhibitor 1 (PAI-1) is associated with the risk of Alzheimer's disease (AD) in Tunisian patients. We analyzed the genotype and allele frequency distribution of the PAI-1 polymorphism in 60 Tunisian patients with AD and 120 healthy controls. The results show a significantly increased risk of AD in carriers of the 4G/4G and 4G/5G genotypes versus the wild-type 5G/5G genotype (4G/4G: 28.33% in patients vs 10.0% in controls; P 5G: 55.0% in patients vs 38.33% in controls; OR = 4.45; P < 10 -3 ). The 4G allele was also more frequently found in patients compared with controls; P < 10 -3 ; OR = 3.07. For all participants and by gender, homozygotic carriers (4G/4G) were at an increased risk of AD over heterozygotes and women were at an increased risk over their male genotype counterparts. The odds ratio for AD among 4G/4G carriers for any group was approximately twice that of heterozygotes in the same group. Women homozygotes ranked highest for AD risk (OR = 20.8) and, in fact, women heterozygotes (OR = 9.03) ranked higher for risk than male homozygotes (OR = 6.12). These preliminary exploratory results should be confirmed in a larger study.

  3. Redshift distributions of galaxies in the Dark Energy Survey Science Verification shear catalogue and implications for weak lensing

    Energy Technology Data Exchange (ETDEWEB)

    Bonnett, C.; Troxel, M. A.; Hartley, W.; Amara, A.; Leistedt, B.; Becker, M. R.; Bernstein, G. M.; Bridle, S. L.; Bruderer, C.; Busha, M. T.; Carrasco Kind, M.; Childress, M. J.; Castander, F. J.; Chang, C.; Crocce, M.; Davis, T. M.; Eifler, T. F.; Frieman, J.; Gangkofner, C.; Gaztanaga, E.; Glazebrook, K.; Gruen, D.; Kacprzak, T.; King, A.; Kwan, J.; Lahav, O.; Lewis, G.; Lidman, C.; Lin, H.; MacCrann, N.; Miquel, R.; O’Neill, C. R.; Palmese, A.; Peiris, H. V.; Refregier, A.; Rozo, E.; Rykoff, E. S.; Sadeh, I.; Sánchez, C.; Sheldon, E.; Uddin, S.; Wechsler, R. H.; Zuntz, J.; Abbott, T.; Abdalla, F. B.; Allam, S.; Armstrong, R.; Banerji, M.; Bauer, A. H.; Benoit-Lévy, A.; Bertin, E.; Brooks, D.; Buckley-Geer, E.; Burke, D. L.; Capozzi, D.; Carnero Rosell, A.; Carretero, J.; Cunha, C. E.; D’Andrea, C. B.; da Costa, L. N.; DePoy, D. L.; Desai, S.; Diehl, H. T.; Dietrich, J. P.; Doel, P.; Fausti Neto, A.; Fernandez, E.; Flaugher, B.; Fosalba, P.; Gerdes, D. W.; Gruendl, R. A.; Honscheid, K.; Jain, B.; James, D. J.; Jarvis, M.; Kim, A. G.; Kuehn, K.; Kuropatkin, N.; Li, T. S.; Lima, M.; Maia, M. A. G.; March, M.; Marshall, J. L.; Martini, P.; Melchior, P.; Miller, C. J.; Neilsen, E.; Nichol, R. C.; Nord, B.; Ogando, R.; Plazas, A. A.; Reil, K.; Romer, A. K.; Roodman, A.; Sako, M.; Sanchez, E.; Santiago, B.; Smith, R. C.; Soares-Santos, M.; Sobreira, F.; Suchyta, E.; Swanson, M. E. C.; Tarle, G.; Thaler, J.; Thomas, D.; Vikram, V.; Walker, A. R.

    2016-08-01

    We present photometric redshift estimates for galaxies used in the weak lensing analysis of the Dark Energy Survey Science Verification (DES SV) data. Four model- or machine learning-based photometric redshift methods { annz2, bpz calibrated against BCC-U fig simulations, skynet, and tpz { are analysed. For training, calibration, and testing of these methods, we also construct a catalogue of spectroscopically confirmed galaxies matched against DES SV data. The performance of the methods is evalu-ated against the matched spectroscopic catalogue, focusing on metrics relevant for weak lensing analyses, with additional validation against COSMOS photo-zs. From the galaxies in the DES SV shear catalogue, which have mean redshift 0.72 ±0.01 over the range 0:3 < z < 1:3, we construct three tomographic bins with means of z = {0.45; 0.67,1.00g}. These bins each have systematic uncertainties δz ≲ 0.05 in the mean of the fiducial skynet photo-z n(z). We propagate the errors in the redshift distributions through to their impact on cosmological parameters estimated with cosmic shear, and find that they cause shifts in the value of σ8 of approx. 3%. This shift is within the one sigma statistical errors on σ8 for the DES SV shear catalog. We also found that further study of the potential impact of systematic differences on the critical surface density, Σcrit, contained levels of bias safely less than the statistical power of DES SV data. We recommend a final Gaussian prior for the photo-z bias in the mean of n(z) of width 0:05 for each of the three tomographic bins, and show that this is a sufficient bias model for the corresponding cosmology analysis.

  4. CERES ERBE-like Monthly Geographical Averages (ES-4) in HDF (CER_ES4_Terra-FM2_Edition1-CV)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    The ERBE-like Monthly Geographical Averages (ES-4) product contains a month of space and time averaged Clouds and the Earth's Radiant Energy System (CERES) data for a single scanner instrument. The ES-4 is also produced for combinations of scanner instruments. For each observed 2.5-degree spatial region, the daily average, the hourly average over the month, and the overall monthly average of shortwave and longwave fluxes at the Top-of-the-Atmosphere (TOA) from the CERES ES-9 product are spatially nested up from 2.5-degree regions to 5- and 10-degree regions, to 2.5-, 5-, and 10-degree zonal averages, and to global monthly averages. For each nested area, the albedo and net flux are given. For each region, the daily average flux is estimated from an algorithm that uses the available hourly data, scene identification data, and diurnal models. This algorithm is 'like' the algorithm used for the Earth Radiation Budget Experiment (ERBE). The following CERES ES4 data sets are currently available: CER_ES4_FM1+FM2_Edition1 CER_ES4_PFM+FM1+FM2_Edition1 CER_ES4_PFM+FM1+FM2_Edition2 CER_ES4_PFM+FM1_Edition1 CER_ES4_PFM+FM2_Edition1 CER_ES4_TRMM-PFM_Edition1 CER_ES4_TRMM-PFM_Edition2 CER_ES4_Terra-FM1_Edition1 CER_ES4_Terra-FM2_Edition1 CER_ES4_FM1+FM2_Edition2 CER_ES4_Terra-FM1_Edition2 CER_ES4_Terra-FM2_Edition2 CER_ES4_Aqua-FM3_Edition1 CER_ES4_Aqua-FM4_Edition1 CER_ES4_FM1+FM2+FM3+FM4_Edition1 CER_ES4_Aqua-FM3_Edition2 CER_ES4_Aqua-FM4_Edition2 CER_ES4_FM1+FM3_Edition2 CER_ES4_FM1+FM4_Edition2 CER_ES4_PFM+FM1_Edition2 CER_ES4_PFM+FM2_Edition2 CER_ES4_Aqua-FM3_Edition1-CV CER_ES4_Aqua-FM4_Edition1-CV CER_ES4_Terra-FM1_Edition1-CV CER_ES4_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1998-01-01; Stop_Date=2006-10-31] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Latitude_Resolution=2.5 degree; Longitude_Resolution=2.5 degree; Horizontal

  5. CERES ERBE-like Monthly Geographical Averages (ES-4) in HDF (CER_ES4_Aqua-FM4_Edition1-CV)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    The ERBE-like Monthly Geographical Averages (ES-4) product contains a month of space and time averaged Clouds and the Earth's Radiant Energy System (CERES) data for a single scanner instrument. The ES-4 is also produced for combinations of scanner instruments. For each observed 2.5-degree spatial region, the daily average, the hourly average over the month, and the overall monthly average of shortwave and longwave fluxes at the Top-of-the-Atmosphere (TOA) from the CERES ES-9 product are spatially nested up from 2.5-degree regions to 5- and 10-degree regions, to 2.5-, 5-, and 10-degree zonal averages, and to global monthly averages. For each nested area, the albedo and net flux are given. For each region, the daily average flux is estimated from an algorithm that uses the available hourly data, scene identification data, and diurnal models. This algorithm is 'like' the algorithm used for the Earth Radiation Budget Experiment (ERBE). The following CERES ES4 data sets are currently available: CER_ES4_FM1+FM2_Edition1 CER_ES4_PFM+FM1+FM2_Edition1 CER_ES4_PFM+FM1+FM2_Edition2 CER_ES4_PFM+FM1_Edition1 CER_ES4_PFM+FM2_Edition1 CER_ES4_TRMM-PFM_Edition1 CER_ES4_TRMM-PFM_Edition2 CER_ES4_Terra-FM1_Edition1 CER_ES4_Terra-FM2_Edition1 CER_ES4_FM1+FM2_Edition2 CER_ES4_Terra-FM1_Edition2 CER_ES4_Terra-FM2_Edition2 CER_ES4_Aqua-FM3_Edition1 CER_ES4_Aqua-FM4_Edition1 CER_ES4_FM1+FM2+FM3+FM4_Edition1 CER_ES4_Aqua-FM3_Edition2 CER_ES4_Aqua-FM4_Edition2 CER_ES4_FM1+FM3_Edition2 CER_ES4_FM1+FM4_Edition2 CER_ES4_PFM+FM1_Edition2 CER_ES4_PFM+FM2_Edition2 CER_ES4_Aqua-FM3_Edition1-CV CER_ES4_Aqua-FM4_Edition1-CV CER_ES4_Terra-FM1_Edition1-CV CER_ES4_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1998-01-01; Stop_Date=2005-03-29] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Latitude_Resolution=2.5 degree; Longitude_Resolution=2.5 degree; Horizontal

  6. Basal transcription of APOBEC3G is regulated by USF1 gene in hepatocyte

    Energy Technology Data Exchange (ETDEWEB)

    Zeng, Yanli [Department of Infectious Diseases, Zhengzhou University People' s Hospital (Henan Provincial People' s Hospital), Zhengzhou, 450003 (China); Li, Hui [The Central Hospital of Wuhan, Tongji Medical College Huazhong University of Science Technology, Wuhan, 430000 (China); Zhang, Xiaoju [Department of Respiratory Medicine, Zhengzhou University People' s Hospital (Henan Provincial People' s Hospital), Zhengzhou, 450003 (China); Shang, Jia [Department of Infectious Diseases, Zhengzhou University People' s Hospital (Henan Provincial People' s Hospital), Zhengzhou, 450003 (China); Kang, Yi, E-mail: kykangyi@163.com [Department of Infectious Diseases, Zhengzhou University People' s Hospital (Henan Provincial People' s Hospital), Zhengzhou, 450003 (China)

    2016-01-29

    Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G, A3G) exert antiviral defense as an important factor of innate immunity. A variety of cytokines such as IFN-γ,IL2,IL15,IL7 could induce the transcription of A3G. However, the regulation of other nuclear factor on the transcription of A3G have not been reported at the present. To gain new insights into the transcriptional regulation of this restriction factor, we cloned and characterized the promoter region of A3G and investigate the modulation of USF1 gene on the transcription of A3G. We identified a 232 bp region that was sufficient to regulate the activity of full promoter. Transcriptional start sites (TSS) were identified by the luciferase reporter assays of plasmids containing full or shorter fragments of the A3G promoter. The results demonstrated that the core promoter of A3G is located within the region -159/-84 relative to the TSS. Transcriptional activity of A3G core promoter regulated by USF1 was dependent on an E-box (located at position -91/-86 relative to the major TSS) and was abolished after mutation of this DNA element. USF1 gene can take part in basal transcription regulation of the human A3G gene in hepatocyte, and the identified E-box represented a binding site for the USF1. - Highlights: • The core promoter of A3G is located within the region −159/−84 relative to the TSS. • Transcriptional activity of A3G core promoter regulated by USF1 was dependent on an E-box (located at position −91/−86 relative to the major TSS). • USF1 gene can take part in basal transcription regulation of the human A3G gene in hepatocyte.

  7. Basal transcription of APOBEC3G is regulated by USF1 gene in hepatocyte

    International Nuclear Information System (INIS)

    Zeng, Yanli; Li, Hui; Zhang, Xiaoju; Shang, Jia; Kang, Yi

    2016-01-01

    Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G (APOBEC3G, A3G) exert antiviral defense as an important factor of innate immunity. A variety of cytokines such as IFN-γ,IL2,IL15,IL7 could induce the transcription of A3G. However, the regulation of other nuclear factor on the transcription of A3G have not been reported at the present. To gain new insights into the transcriptional regulation of this restriction factor, we cloned and characterized the promoter region of A3G and investigate the modulation of USF1 gene on the transcription of A3G. We identified a 232 bp region that was sufficient to regulate the activity of full promoter. Transcriptional start sites (TSS) were identified by the luciferase reporter assays of plasmids containing full or shorter fragments of the A3G promoter. The results demonstrated that the core promoter of A3G is located within the region -159/-84 relative to the TSS. Transcriptional activity of A3G core promoter regulated by USF1 was dependent on an E-box (located at position -91/-86 relative to the major TSS) and was abolished after mutation of this DNA element. USF1 gene can take part in basal transcription regulation of the human A3G gene in hepatocyte, and the identified E-box represented a binding site for the USF1. - Highlights: • The core promoter of A3G is located within the region −159/−84 relative to the TSS. • Transcriptional activity of A3G core promoter regulated by USF1 was dependent on an E-box (located at position −91/−86 relative to the major TSS). • USF1 gene can take part in basal transcription regulation of the human A3G gene in hepatocyte.

  8. Program Aplikasi Optimalisasi Perencanaan Produksi Dengan Metode Goal Programming (Kasus Cv. G

    Directory of Open Access Journals (Sweden)

    Zahedi Zahedi

    2010-06-01

    Full Text Available Indonesia today is still a State agrarian. Thus agriculture in Indonesia always get more attention by the government. Many government programs are rolled out to support the agricultural development of Indonesia, and one of them is the fertilizer subsidy to farmers Indonesia. Fertilizer itself is very useful to nourish the soil and provide vitamins to the plants, thus increasing the amount of production generated. Therefore it is necessary fertilizer for agriculture in Indonesia. CV. G company is one of the companies that produce fertilizer. Fertilizer produced by this company is an organic fertilizer and inorganic fertilizer. Problems faced by these companies are in planning the production of fertilizer produced. Companies want to optimize the amount of production of each fertilizer, maximize revenues, minimize production costs, and simultaneously optimize the working hours of employees. To meet these objectives, this research created program package using goal programming methods. Goal programming method can provide an effective solution / equilibrium toward the goals set, and the calculation will be assisted by using the Simplex method that has been modified. This method is an extension of linear programming, linear programming which can only solve problems with a single goal while the goal programming to solve problems with multiple objectives.

  9. Library catalogues as resources for book history: case study of Novosel’s bookstore catalogue in Zagreb (1794 - 1825

    Directory of Open Access Journals (Sweden)

    Marijana Tomić

    2008-07-01

    Full Text Available The aim of the paper is to analyze the book catalogue of Novosel’s bookstore, which operated in Zagreb from 1794 to 1825, and investigate the history of books and writing in Zagreb at the turn of the 19th century. The catalogue we analyzed is believed to have been published in 1801. Bearing in mind that the market-based economy started to develop in the late 18th century, it can be stipulated that Novosel and his staff and successors based the offer in their bookstore on market analysis, i.e. their readers’ needs. The increase in offer has sparked off new advertising techniques, i.e. printing of catalogues. It follows that their book catalogue reflects the image of the cultural and intellectual status and needs of readers in those times. The paper provides a short overview of book trade in the late 18th century Zagreb and of bookstore advertisements published both in books and individually, as well as a short overview of Novosel’s bookstore business. In the analysis we partly use the methodology introduced by Robert Darnton, the so-called Darnton’s circle, which takes a holistic view of the history of books taking into consideration all stages a book needs to go through - from the author, publisher, printer, bookstores, to readers, including the author him/herself as a reader. Every element is considered in relation to other elements in the circle, and in connection with external factors such as the economic and social environment, and political and intellectual influences. The books presented in the catalogue have been analyzed using different criteria: language, genre and country where they were printed. Books printed in Croatia and those written in Croatian have been given priority. In the catalogue analysis we used the database Skupni katalog hrvatskih knjižnica (joint Croatian library catalogue in order to reconstruct the printing year and printing shops that have not been listed in the catalogues. Using this methodology, we partly

  10. Efeito de reguladores de crescimento em uva apirênica, cv. BRS Clara Effect of growth regulators on the seedless grape cv. BRS Clara

    Directory of Open Access Journals (Sweden)

    Jair Costa Nachtigal

    2005-08-01

    Full Text Available O presente trabalho teve por objetivo verificar o efeito da aplicação de diferentes concentrações do ácido giberélico (AG3, do thidiazuron (TDZ e do forchlorfenuron (CPPU no aumento do tamanho dos cachos e das bagas e no teor de sólidos solúveis totais de uva sem semente, cv. BRS Clara. As plantas foram conduzidas no sistema de latada, sobre o porta-enxerto IAC 572, no espaçamento 2,5 x 2,0m e com irrigação por microaspersão. Os experimentos foram conduzidos na Estação Experimental de Viticultura Tropical, da Embrapa Uva e Vinho, em Jales-SP. Os reguladores de crescimento foram aplicados via pulverização localizada no cacho, utilizando-se de concentrações de 0 a 4mg.L-1 de CPPU; 0 a 10mg.L-1 de TDZ, e de 0 a 90mg.L-1 de AG3, isolados ou em conjunto. De modo geral, a aplicação dos reguladores de crescimento promove a melhoria da qualidade dos cachos da cv. BRS Clara; o uso do TDZ e do CPPU em conjunto com o AG3 produz um efeito sinérgico, proporcionando melhor resposta do que o uso isolado do AG3; os tratamentos com 60mg.L-1 de AG3; 20mg.L-1 de AG3 + 4mg.L-1 de CPPU, e 10mg.L-1 de AG3 + 5mg.L-1 de TDZ proporcionam os melhores resultados para o aumento do diâmetro das bagas; a aplicação de AG3 antes da floração da cv. BRS Clara provoca abortamento excessivo, reduzindo a qualidade comercial dos cachos; a utilização de concentrações elevadas dos reguladores reduz o teor de sólidos solúveis totais.The objective of this study was to evaluate the effect of different concentrations of gibberellic acid (AG3, thidiazuron (TDZ and forchlorfenuron (CPPU on the size of bunches and berries and on the total soluble solids content, when applied in different concentrations on the seedless grapes, cv. BRS Clara. The grapevines were grafted on the rootstock IAC 572, trained in the pergola system and, spaced 2.5 x 2.0m and irrigated by micro sprinklers. The experiments were carried out at the Embrapa Grape and Wine Experimental

  11. Cataloguing In Special Libraries In The 1990s

    Directory of Open Access Journals (Sweden)

    Elizabeth Makin

    1996-01-01

    Full Text Available Cataloguing in special libraries has been virtually ignored in the literature since the turn of the century, although there are many books and papers on cataloguing in general. It is not clear why this should be so, since it can be argued that the needs of special libraries are different from those of public, academic and national libraries. Special libraries are primarily interested in the information content of documents in the sense that they have little or no interest in documents except as "packages" in which information may be encapsulated. It is therefore reasonable to assume, a priori, that special libraries would undertake detailed indexing and light cataloguing, perhaps reducing the catalogue to the status of a finding list. This paper reports the results of a survey of current cataloguing practice in special libraries.

  12. The prevalence of 4G/5G polymorphism of plasminogen activator inhibitor-1 (PAI-1) gene in central serous chorioretinopathy and its association with plasma PAI-1 levels.

    Science.gov (United States)

    Sogutlu Sari, Esin; Yazici, Alper; Eser, Betül; Erol, Muhammet Kazim; Kilic, Adil; Ermis, Sitki Samet; Koytak, Arif; Akşit, Hasan; Yakut, Tahsin

    2014-12-01

    Central serous chorioretinopathy (CSCR) is a poorly understood disease and the choroidal circulation abnormality induced by the plasminogen activator inhibitor type 1 (PAI-1) seems to be associated with the pathogenesis. There are many reports indicating that 4 G/5 G polymorphism of the PAI-1 gene is a risk factor for several diseases related to the elevated serum levels of PAI-1. To evaluate the 4 G/5 G polymorphism of the PAI-1 gene and its association with serum levels of PAI-1 in acute CSCR patients. Sixty CSCR patients and 50 healthy control patients were included. The PAI-1 4 G/5 G was genotyped using the polymerase chain reaction-restriction technique. Serum PAI-1 level was measured using enzyme-linked immunosorbent assay. Demographic data consisting of age, sex, body mass index (BMI) as well as genotype disturbances and serum PAI-1 levels were compared between the groups. Statistical significance for differences in the serum PAI-1 levels of each group with different genotypes was also analyzed. The CSCR group consisted of 40 male (66.7%) and 20 female (33.3%) patients with a mean age of 46.7 ± 8.39 years. The control group consisted of 32 male (64%) and 18 female (36%) healthy subjects with a mean age of 45.8 ± 8.39 years. There was no statistically significant difference between the groups in terms of age, sex and BMI. In the CSCR group the genotype frequencies were 4 G/4G: 30% (n = 18), 4G/5 G: 50% (n = 30), 5 G/5G: 20% (n = 12) and in the control group genotype frequencies were 34% (n = 17), 42% (n = 21) and 24% (n = 12), respectively. There was no statistically significant difference in the distribution of genotypes among the groups (chi-squared, p = 0.70). The CSCR group had a significantly higher serum PAI-1 concentration than the control group (p = 0.001). In both groups the mean plasma PAI-1 concentration did not vary significantly among the different genotypes (p > 0.05). Although our results demonstrated that the patients with acute CSCR have

  13. Nutritive evaluation of Medicago truncutula (cv. jernalong) pasture ...

    African Journals Online (AJOL)

    Nutritive evaluation of Medicago truncutula (cv. jernalong) pasture for sheep. 1. Seasonal .... obtained by laboratory work, using in vitro techniques. (Engels et al. .... model that was used to explain 92,3% of the variance in. IVDOM content.

  14. Catalogue of Korean manuscripts and rare books

    DEFF Research Database (Denmark)

    Lerbæk Pedersen, Bent

    2014-01-01

    Catalogue of Korean manuscripts and rare books in The Royal Library, Copenhagen and the National Museum of Denmark......Catalogue of Korean manuscripts and rare books in The Royal Library, Copenhagen and the National Museum of Denmark...

  15. THE INFLUENCE OF POTATO CYST NEMATODE G. ROSTOCHIENSIS INFESTATION ON DIFFERENT POTATO CULTIVARS

    Directory of Open Access Journals (Sweden)

    Gregor Urek

    2008-07-01

    Full Text Available The potato cyst nematode Globodera rostochiensis is one of the most serious pests of potato in Slovenia. Precise nematode identification and knowledge about potato cultivars, which are most suitable for growing in the Slovenian climate conditions and most resistant to G. rostochiensis, are necessary to develop an effective integrated pest control. Here we report the results of the influence of G. rostochiensis pathotype Ro1/4 on the yield of different potato cultivars: the susceptible cultivar Desiree, the resistant cultivars White Lady, Miranda, Aladin, Sante and Adora, and the clone KIS 94-1/5-14. The yield of cv. White Lady was the highest and that of susceptible cv. Desiree the lowest. The influence of several resistant and one susceptible potato cultivars on population dynamics of G. rostochiensis was also determined. The total number of cysts/100 cm3 and the number of eggs and juveniles per cyst increased in the susceptible cv. Desiree and decreased in the resistant cultivars White Lady, Sante and Adora.

  16. QRLs for tomato powdery mildew resisance (Oidium lycopersici) in Lycopersicon parviflorum G1.1601 colocalize with two qualitative powdery mildew resistance genes

    NARCIS (Netherlands)

    Bai, Y.; Huang, C.C.; Hulst, van der R.G.M.; Meijer-Dekens, R.G.; Bonnema, A.B.; Lindhout, W.H.

    2003-01-01

    Tomato (Lycopersicon esculentum) is susceptible to the powdery mildew Oidium lycopersici, but several wild relatives such as Lycopersicon parviflorum G1.1601 are completely resistant. An F-2 population from a cross of Lycopersicon esculentum cv. Moneymaker x Lycopersicon parviflorum G1.1601 was used

  17. Towards a Next-Generation Catalogue Cross-Match Service

    Science.gov (United States)

    Pineau, F.; Boch, T.; Derriere, S.; Arches Consortium

    2015-09-01

    We have been developing in the past several catalogue cross-match tools. On one hand the CDS XMatch service (Pineau et al. 2011), able to perform basic but very efficient cross-matches, scalable to the largest catalogues on a single regular server. On the other hand, as part of the European project ARCHES1, we have been developing a generic and flexible tool which performs potentially complex multi-catalogue cross-matches and which computes probabilities of association based on a novel statistical framework. Although the two approaches have been managed so far as different tracks, the need for next generation cross-match services dealing with both efficiency and complexity is becoming pressing with forthcoming projects which will produce huge high quality catalogues. We are addressing this challenge which is both theoretical and technical. In ARCHES we generalize to N catalogues the candidate selection criteria - based on the chi-square distribution - described in Pineau et al. (2011). We formulate and test a number of Bayesian hypothesis which necessarily increases dramatically with the number of catalogues. To assign a probability to each hypotheses, we rely on estimated priors which account for local densities of sources. We validated our developments by comparing the theoretical curves we derived with the results of Monte-Carlo simulations. The current prototype is able to take into account heterogeneous positional errors, object extension and proper motion. The technical complexity is managed by OO programming design patterns and SQL-like functionalities. Large tasks are split into smaller independent pieces for scalability. Performances are achieved resorting to multi-threading, sequential reads and several tree data-structures. In addition to kd-trees, we account for heterogeneous positional errors and object's extension using M-trees. Proper-motions are supported using a modified M-tree we developed, inspired from Time Parametrized R-trees (TPR

  18. Leaf anatomy of cassava (Manihot esculenta Crantz. cv. IAC-12 after herbicides application to control weeds in Minas Gerais, Brazil

    Directory of Open Access Journals (Sweden)

    Daniel Valadão Silva

    2017-07-01

    Full Text Available Micro-morphological changes precede the appearance of visible damage after herbicide application and are essential in providing data for the safe recommendation in chemical management of weeds. Therefore, the aim of this research was to verify the anatomical changes of leaf tissue caused by application of herbicides in cassava (Manihot esculenta Crantz. cv. IAC-12. A greenhouse experiment was conducted with post-emergence herbicides treatments as follows: nicossulfuron (60 g a.i ha-1, fluazifop (250 g a.i ha-1, fomesafem (250 g a.i ha-1, metribuzin (480 g a.i ha-1, oxyfluorfen (720 g a.i ha-1 and the mixture fluazifop + fomesafen (200 + 250 g a.i ha-1, and an untreated control, respectively. The results obtained have allowed to affirm the cassava plants (cultivar IAC-12, exhibited changes in leaf anatomy in response to herbicide application even on cassava leaves without no visual toxicity symptoms. The products caused alterations both in tissue thickness as in tissue proportion in the leaf blade. For the fluazifop, a eudicotyledonous selective herbicide, changes were observed in tissue thickness and proportion of leaf blade, even without any visual toxicity detected. Cassava plants (IAC-12, showed structural changes in leaf anatomy in response to application of herbicides. The leaf anatomy of cassava cv. IAC-12, can be used to indicate the herbicide effect on cassava (Manihot esculenta Crantz.cv. IAC-12 plants.

  19. Addressing the Challenge: Cataloguing Electronic Books in Academic Libraries

    Directory of Open Access Journals (Sweden)

    Shuzhen Zhao

    2010-03-01

    Full Text Available Objective ‐ This paper explores the various issues and challenges arising from e‐book cataloguing experienced at the University of Windsor’s Leddy Library and the Ontario Council of University Libraries (OCUL. This discussion uses an evidence based approach to identify and resolve issues relevant to academic libraries as well as to consortia. With the ever rising popularity of e‐books within academic libraries, cataloguing librarians are actively seeking more effective methods of managing this new electronic medium, including the development of new cataloguing policies and procedures. This paper will explore the various issues and challenges surrounding e‐book cataloguing and processing within academic libraries, and will identify new policies and procedures that may be used to effectively assist in e‐book management.Methods ‐ This paper presents a case study of e‐book cataloguing practices undertaken by a Canadian academic library and the consortium with which it is affiliated. Towards this end, the University of Windsor’s Leddy Library will be the prime focus of this study, with its establishment of a new e‐book MARC records database. The research is based on the results of the e‐book MARC project undertaken by the Leddy Library and the Ontario Council of University Libraries (OCUL.Through analysis of various suppliers’ MARC records and the actual implementation of the e‐book MARC project, the authors developed and evaluated a new approach to e‐book cataloguing for use in academic libraries.Results ‐ This practice‐based approach towards the development of a new method of e‐book cataloguing required continual modification and examination of e‐book MARC records within the target library. The Leddy Library’s e‐book MARC project provided an excellent opportunity to test the library’s existing cataloguing standards and procedures for print format, while at the same time, identifying related e‐books issues

  20. On the moroccan tsunami catalogue

    Directory of Open Access Journals (Sweden)

    F. Kaabouben

    2009-07-01

    Full Text Available A primary tool for regional tsunami hazard assessment is a reliable historical and instrumental catalogue of events. Morocco by its geographical situation, with two marine sides, stretching along the Atlantic coast to the west and along the Mediterranean coast to the north, is the country of Western Africa most exposed to the risk of tsunamis. Previous information on tsunami events affecting Morocco are included in the Iberian and/or the Mediterranean lists of tsunami events, as it is the case of the European GITEC Tsunami Catalogue, but there is a need to organize this information in a dataset and to assess the likelihood of claimed historical tsunamis in Morocco. Due to the fact that Moroccan sources are scarce, this compilation rely on historical documentation from neighbouring countries (Portugal and Spain and so the compatibility between the new tsunami catalogue presented here and those that correspond to the same source areas is also discussed.

  1. Catalogue of HI PArameters (CHIPA)

    Science.gov (United States)

    Saponara, J.; Benaglia, P.; Koribalski, B.; Andruchow, I.

    2015-08-01

    The catalogue of HI parameters of galaxies HI (CHIPA) is the natural continuation of the compilation by M.C. Martin in 1998. CHIPA provides the most important parameters of nearby galaxies derived from observations of the neutral Hydrogen line. The catalogue contains information of 1400 galaxies across the sky and different morphological types. Parameters like the optical diameter of the galaxy, the blue magnitude, the distance, morphological type, HI extension are listed among others. Maps of the HI distribution, velocity and velocity dispersion can also be display for some cases. The main objective of this catalogue is to facilitate the bibliographic queries, through searching in a database accessible from the internet that will be available in 2015 (the website is under construction). The database was built using the open source `` mysql (SQL, Structured Query Language, management system relational database) '', while the website was built with ''HTML (Hypertext Markup Language)'' and ''PHP (Hypertext Preprocessor)''.

  2. CERES ERBE-like Monthly Regional Averages (ES-9) in HDF ( CER_ES9_Aqua-FM4_Edition1-CV)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    The ERBE-like Monthly Regional Averages (ES-9) product contains a month of space and time averaged Clouds and the Earth's Radiant Energy System (CERES) data for a single scanner instrument. The ES-9 is also produced for combinations of scanner instruments. All instantaneous shortwave and longwave fluxes at the Top-of-the-Atmosphere (TOA) from the CERES ES-8 product for a month are sorted by 2.5-degree spatial regions, by day number, and by the local hour of observation. The mean of the instantaneous fluxes for a given region-day-hour bin is determined and recorded on the ES-9 along with other flux statistics and scene information. For each region, the daily average flux is estimated from an algorithm that uses the available hourly data, scene identification data, and diurnal models. This algorithm is 'like' the algorithm used for the Earth Radiation Budget Experiment (ERBE). The ES-9 also contains hourly average fluxes for the month and an overall monthly average for each region. These average fluxes are given for both clear-sky and total-sky scenes. The following CERES ES9 data sets are currently available: CER_ES9_FM1+FM2_Edition1 CER_ES9_PFM+FM1+FM2_Edition1 CER_ES9_PFM+FM1+FM2_Edition2 CER_ES9_PFM+FM1_Edition1 CER_ES9_PFM+FM2_Edition1 CER_ES9_PFM+FM1_Edition2 CER_ES9_PFM+FM2_Edition2 CER_ES9_TRMM-PFM_Edition1 CER_ES9_TRMM-PFM_Edition2 CER_ES9_Terra-FM1_Edition1 CER_ES9_Terra-FM2_Edition1 CER_ES9_FM1+FM2_Edition2 CER_ES9_Terra-FM1_Edition2 CER_ES9_Terra-FM2_Edition2 CER_ES9_Aqua-FM3_Edition1 CER_ES9_Aqua-FM4_Edition1 CER_ES9_FM1+FM2+FM3+FM4_Edition1 CER_ES9_Aqua-FM3_Edition2 CER_ES9_Aqua-FM4_Edition2 CER_ES9_FM1+FM3_Edition2 CER_ES9_FM1+FM4_Edition2 CER_ES9_Aqua-FM3_Edition1-CV CER_ES9_Aqua-FM4_Edition1-CV CER_ES9_Terra-FM1_Edition1-CV CER_ES9_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1998-01-01; Stop_Date=2005-03-29] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost

  3. A comparison of aphasic and non-brain-injured adults on a dichotic CV-syllable listening task.

    Science.gov (United States)

    Shanks, J; Ryan, W

    1976-06-01

    A dichotic CV-syllable listening task was administered to a group of eleven non-brain-injured adults and to a group of eleven adult aphasics. The results of this study may be summarized as follows: 1)The group of non-brain-injured adults showed a slight right ear advantage for dichotically presented CV-syllables. 2)In comparison with the control group the asphasic group showed a bilateral deficit in response to the dichotic CV-syllables, superimposed on a non-significant right ear advantage. 3) The asphasic group demonstrated a great deal of intersubject variability on the dichotic task with six aphasics showing a right ear preference for the stimuli. The non-brain-injured subjects performed more homogeneously on the task. 4) The two subgroups of aphasics, a right ear advantage group and a left ear advantage group, performed significantly different on the dichotic listening task. 5) Single correct data analysis proved valuable by deleting accuracy of report for an examination of trials in which there was true competition for the single left hemispheric speech processor. These results were analyzed in terms of a functional model of auditory processing. In view of this model, the bilateral deficit in dichotic performance of the asphasic group was accounted for by the presence of a lesion within the dominant left hemisphere, where the speech signals from both ears converge for final processing. The right ear advantage shown by one asphasic subgroup was explained by a lesion interfering with the corpus callosal pathways from the left hemisphere; the left ear advantage observed within the other subgroup was explained by a lesion in the area of the auditory processor of the left hemisphere.

  4. A randomised trial to evaluate the immunogenicity, reactogenicity, and safety of the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) co-administered with routine childhood vaccines in Singapore and Malaysia.

    Science.gov (United States)

    Lim, Fong Seng; Koh, Mia Tuang; Tan, Kah Kee; Chan, Poh Chong; Chong, Chia Yin; Shung Yehudi, Yeo Wee; Teoh, Yee Leong; Shafi, Fakrudeen; Hezareh, Marjan; Swinnen, Kristien; Borys, Dorota

    2014-10-02

    The immunogenicity, reactogenicity, and safety of the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) co-administered with routine childhood vaccines were evaluated among infants from Singapore and Malaysia, where PHiD-CV has been licensed. In the primary vaccination phase, 298 infants from Singapore and 168 infants from Malaysia were randomised to receive the Phase III Clinical (Clin) or the Commercial (Com) lot of PHiD-CV at 2, 3, and 5 months of age. In the booster vaccination phase, 238 toddlers from Singapore received one dose of the PHiD-CV Commercial lot at 18-21 months of age. Immune responses to pneumococcal polysaccharides were measured using 22F-inhibition enzyme-linked immunosorbent assay (ELISA) and functional opsonophagocytic activity (OPA) assay and to protein D, using ELISA. Immune responses induced by primary vaccination with the PHiD-CV Commercial lot were non-inferior to the Phase III Clinical lot in terms of adjusted antibody geometric mean concentration (GMC) ratios for each vaccine pneumococcal serotype and protein D. For each vaccine pneumococcal serotype, ≥93.6% and ≥88.5% of infants from Malaysia and Singapore had post-primary vaccination antibody concentrations ≥0.2 μg/mL and OPA titres ≥8, in the Clin and Com groups, respectively. For each vaccine pneumococcal serotype, ≥60.8% and ≥98.2% of toddlers from Singapore had pre- and post-booster antibody concentrations ≥0.2 μg/mL, in the Clin and Com groups, respectively. All children, except one, had measurable anti-protein D antibodies and the primary and booster doses of the co-administered vaccines were immunogenic. The incidence of each grade 3 solicited symptom was ≤11.1% in both study phases. No serious adverse events considered causally related to vaccination were reported throughout the study. PHiD-CV given as three-dose primary vaccination to infants in Singapore and Malaysia and booster vaccination to toddlers in

  5. Catalogue of Exoplanets in Multiple-Star-Systems

    Science.gov (United States)

    Schwarz, Richard; Funk, Barbara; Bazsó, Ákos; Pilat-Lohinger, Elke

    2017-07-01

    Cataloguing the data of exoplanetary systems becomes more and more important, due to the fact that they conclude the observations and support the theoretical studies. Since 1995 there is a database which list most of the known exoplanets (The Extrasolar Planets Encyclopaedia is available at http://exoplanet.eu/ and described at Schneider et al. 2011). With the growing number of detected exoplanets in binary and multiple star systems it became more important to mark and to separate them into a new database. Therefore we started to compile a catalogue for binary and multiple star systems. Since 2013 the catalogue can be found at http://www.univie.ac.at/adg/schwarz/multiple.html (description can be found at Schwarz et al. 2016) which will be updated regularly and is linked to the Extrasolar Planets Encyclopaedia. The data of the binary catalogue can be downloaded as a file (.csv) and used for statistical purposes. Our database is divided into two parts: the data of the stars and the planets, given in a separate list. Every columns of the list can be sorted in two directions: ascending, meaning from the lowest value to the highest, or descending. In addition an introduction and help is also given in the menu bar of the catalogue including an example list.

  6. Catalogue of Meteor Showers and Storms in Korean History

    Directory of Open Access Journals (Sweden)

    Sang-Hyeon Ahn

    2004-03-01

    Full Text Available We present a more complete and accurate catalogue of astronomical records for meteor showers and meteor storms appeared in primary official Korean history books, such as Samguk-sagi, Koryo-sa, Seungjeongwon-ilgi, and Choson-Wangjo-Sillok. So far the catalogue made by Imoto and Hasegawa in 1958 has been widely used in the international astronomical society. The catalogue is based on a report by Sekiguchi in 1917 that is mainly based on secondary history books. We observed that the catalogue has a number of errors in either dates or sources of the records. We have thoroughly checked the primary official history books, instead of the secondary ones, in order to make a corrected and extended catalogue. The catalogue contains 25 records of meteor storms, four records of intense meteor-showers, and five records of usual showers in Korean history. We also find that some of those records seem to correspond to some presently active meteor showers such as the Leonids, the Perseids, and the ¥ç-Aquarids-Orionids pair. However, a large number of those records do not correspond to such present showers. This catalogue we obtained can be useful for various astrophysical studies in the future.

  7. Atmosfera modificada e 1-metilciclopropeno na conservação pós-colheita de kiwis cv. Bruno Modified atmosphere and 1-methylciclopropene on postharvest conservation of kiwis cv. Bruno

    Directory of Open Access Journals (Sweden)

    Leandro Camargo Neves

    2003-12-01

    Full Text Available Neste trabalho avaliou-se, em kiwis da cv Bruno, a ação do 1-Metilciclopropeno (1-MCP, na concentração de 625 ppb, associado ou não à atmosfera modificada gerada com o emprego de embalagem de polietileno de baixa densidade (PEBD, de 22µm. Os tratamentos testados foram: T1, controle (sem embalagem e 1-MCP; T2, sem embalagem com 1-MCP; T3, com embalagem de PEBD sem 1-MCP; T4, embalagem de PEBD mais o 1-MCP, sendo após armazenados em câmara fria a - 0,5 ± 0,5 ºC e 95 ± 5% de umidade relativa (U.R.. As avaliações foram realizadas após o pré-resfriamento, aos 45 dias, 45 + 5 dias (22 ± 3ºC e 75 ± 5% de U.R., 90 dias e 90 + 5 dias (22 ± 3ºC e 75 ± 5% de U.R.. As variáveis analisadas foram: firmeza de polpa (FP, sólidos totais (ST, acidez titulável (AT, concentração de etileno e de CO2 e análise sensorial (somente ao final do experimento. A maior firmeza de polpa e acidez titulável, o menor conteúdo de sólidos totais, as menores concentrações de etileno e CO2 e a melhor aceitabilidade pelos julgadores foi obtida com os frutos acondicionadas em PEBD de 22 µm e tratadas com 1-MCP.In this work was evaluated, for kiwis cv. Bruno, the Methylcyclopropene action (1-MCP, in concentration of 625 ppb, associated or not with modified atmosphere (MA using low density polyethylene bags (LDPE of 22µm. The following treatments were tested: T1: control (no bags and 1-MCP; T2 no bags with 1-MCP; T3 LDPE bags no 1-MCP; T4 LDPE bags and 1-MCP, then they were stored in cold chamber at - 0,5 ± 0,5 ºC and 95 ± 5% of RH for 45 or 90 days. The fruits were evaluated after pre-cooling, 45 days, 45 + 5 days (22 ± 3ºC and 75 ± 5% of RH., 90 days and 90 + 5 days (22 ± 3ºC and 75 ± 5% of RH.. The parameters analyzed were: pulp firmness (PF, total solids (TS, titritable acidity (TA, ethylene and CO2 concentration, and sensorial analyzes (only in the end of the experiment. The largest pulp firmness and titritable acidity, the smaller

  8. Technology Catalogue. First edition

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-01

    The Department of Energy`s Office of Environmental Restoration and Waste Management (EM) is responsible for remediating its contaminated sites and managing its waste inventory in a safe and efficient manner. EM`s Office of Technology Development (OTD) supports applied research and demonstration efforts to develop and transfer innovative, cost-effective technologies to its site clean-up and waste management programs within EM`s Office of Environmental Restoration and Office of Waste Management. The purpose of the Technology Catalogue is to provide performance data on OTD-developed technologies to scientists and engineers assessing and recommending technical solutions within the Department`s clean-up and waste management programs, as well as to industry, other federal and state agencies, and the academic community. OTD`s applied research and demonstration activities are conducted in programs referred to as Integrated Demonstrations (IDs) and Integrated Programs (IPs). The IDs test and evaluate.systems, consisting of coupled technologies, at specific sites to address generic problems, such as the sensing, treatment, and disposal of buried waste containers. The IPs support applied research activities in specific applications areas, such as in situ remediation, efficient separations processes, and site characterization. The Technology Catalogue is a means for communicating the status. of the development of these innovative technologies. The FY93 Technology Catalogue features technologies successfully demonstrated in the field through IDs and sufficiently mature to be used in the near-term. Technologies from the following IDs are featured in the FY93 Technology Catalogue: Buried Waste ID (Idaho National Engineering Laboratory, Idaho); Mixed Waste Landfill ID (Sandia National Laboratories, New Mexico); Underground Storage Tank ID (Hanford, Washington); Volatile organic compound (VOC) Arid ID (Richland, Washington); and VOC Non-Arid ID (Savannah River Site, South Carolina).

  9. Dynamical problems in the preparation of the catalogue of one-apparition comets

    International Nuclear Information System (INIS)

    Sitarski, G.

    1979-01-01

    The idea of recomputing all the orbits of long-period comets arose about ten years ago. The work was undertaken at the Warsaw Astronomical Observatory with the cooperation of Slovakian astronomers at the Astronomical Institute in Bratislava and Tatranska Lomnica. To make reasonable the idea of the new catalogue, the following problems have been taken into consideration when recomputing the cometary orbits: 1. to collect all the observations of one-apparition comets and to reduce them to the one system of star catalogues; 2. to define precisely various types of observations and to include in them the corrections of precession, aberration, etc.; 3. to determine the mathematical criteria for eliminating and weighting the observations; and 4. to take into account nongravitational effects in the comet's motion. (Auth.)

  10. Competencies and materials for repositioning cataloguers for ...

    African Journals Online (AJOL)

    The purpose of this study was to determine the competencies and materials for repositioning cataloguers for information management in an electronic era. The survey method was adopted for the research design using questionnaire for data collection. The population comprised of 44 cataloguers in 12 universities in ...

  11. DIDERO 3G: herramienta para la planificación estratégica de redes móviles híbridas 2G/3G

    OpenAIRE

    Portilla Figueras, José Antonio; Hackbarth Planeta, Klaus Dietrich; Fuente Cosío, Luis P. de la

    2002-01-01

    This paper presents the project DIDERO 3G that the Telematic Engineering Group of the University of Cantabria is going to develop. The aim of DIDERO is to perform strategic network planning for an hybrid 2G/3G Mobile network to provide as a result of this planning tecno-economical reports that could guide a mobile operator to take decissions about when and where to deploy 3G. DIDERO 3G can also serve the National Regulatory Atuhtorities as an objetvive basis to perform mo...

  12. TeV γ-ray observations of the young synchrotron-dominated SNRs G1.9+0.3 and G330.2+1.0 with H.E.S.S.

    Science.gov (United States)

    H.E.S.S. Collaboration; Abramowski, A.; Aharonian, F.; Benkhali, F. Ait; Akhperjanian, A. G.; Angüner, E.; Anton, G.; Balenderan, S.; Balzer, A.; Barnacka, A.; Becherini, Y.; Becker Tjus, J.; Bernlöhr, K.; Birsin, E.; Bissaldi, E.; Biteau, J.; Böttcher, M.; Boisson, C.; Bolmont, J.; Bordas, P.; Brucker, J.; Brun, F.; Brun, P.; Bulik, T.; Carrigan, S.; Casanova, S.; Cerruti, M.; Chadwick, P. M.; Chalme-Calvet, R.; Chaves, R. C. G.; Cheesebrough, A.; Chrétien, M.; Colafrancesco, S.; Cologna, G.; Conrad, J.; Couturier, C.; Cui, Y.; Dalton, M.; Daniel, M. K.; Davids, I. D.; Degrange, B.; Deil, C.; deWilt, P.; Dickinson, H. J.; Djannati-Ataï, A.; Domainko, W.; O'C. Drury, L.; Dubus, G.; Dutson, K.; Dyks, J.; Dyrda, M.; Edwards, T.; Egberts, K.; Eger, P.; Espigat, P.; Farnier, C.; Fegan, S.; Feinstein, F.; Fernandes, M. V.; Fernandez, D.; Fiasson, A.; Fontaine, G.; Förster, A.; Füßling, M.; Gajdus, M.; Gallant, Y. A.; Garrigoux, T.; Giavitto, G.; Giebels, B.; Glicenstein, J. F.; Grondin, M.-H.; Grudzińska, M.; Häffner, S.; Hahn, J.; Harris, J.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hervet, O.; Hillert, A.; Hinton, J. A.; Hofmann, W.; Hofverberg, P.; Holler, M.; Horns, D.; Jacholkowska, A.; Jahn, C.; Jamrozy, M.; Janiak, M.; Jankowsky, F.; Jung, I.; Kastendieck, M. A.; Katarzyński, K.; Katz, U.; Kaufmann, S.; Khélifi, B.; Kieffer, M.; Klepser, S.; Klochkov, D.; Kluźniak, W.; Kneiske, T.; Kolitzus, D.; Komin, Nu.; Kosack, K.; Krakau, S.; Krayzel, F.; Krüger, P. P.; Laffon, H.; Lamanna, G.; Lefaucheur, J.; Lemière, A.; Lemoine-Goumard, M.; Lenain, J.-P.; Lennarz, D.; Lohse, T.; Lopatin, A.; Lu, C.-C.; Marandon, V.; Marcowith, A.; Marx, R.; Maurin, G.; Maxted, N.; Mayer, M.; McComb, T. J. L.; Méhault, J.; Meintjes, P. J.; Menzler, U.; Meyer, M.; Moderski, R.; Mohamed, M.; Moulin, E.; Murach, T.; Naumann, C. L.; de Naurois, M.; Niemiec, J.; Nolan, S. J.; Oakes, L.; Ohm, S.; Wilhelmi, E. de Oña; Opitz, B.; Ostrowski, M.; Oya, I.; Panter, M.; Parsons, R. D.; Arribas, M. Paz; Pekeur, N. W.; Pelletier, G.; Perez, J.; Petrucci, P.-O.; Peyaud, B.; Pita, S.; Poon, H.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raab, S.; Raue, M.; Reimer, A.; Reimer, O.; Renaud, M.; Reyes, R. de los; Rieger, F.; Rob, L.; Romoli, C.; Rosier-Lees, S.; Rowell, G.; Rudak, B.; Rulten, C. B.; Sahakian, V.; Sanchez, D. A.; Santangelo, A.; Schlickeiser, R.; Schüssler, F.; Schulz, A.; Schwanke, U.; Schwarzburg, S.; Schwemmer, S.; Sol, H.; Spengler, G.; Spies, F.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stinzing, F.; Stycz, K.; Sushch, I.; Szostek, A.; Tavernet, J.-P.; Tavernier, T.; Taylor, A. M.; Terrier, R.; Tluczykont, M.; Trichard, C.; Valerius, K.; van Eldik, C.; van Soelen, B.; Vasileiadis, G.; Venter, C.; Viana, A.; Vincent, P.; Völk, H. J.; Volpe, F.; Vorster, M.; Vuillaume, T.; Wagner, S. J.; Wagner, P.; Ward, M.; Weidinger, M.; Weitzel, Q.; White, R.; Wierzcholska, A.; Willmann, P.; Wörnlein, A.; Wouters, D.; Zabalza, V.; Zacharias, M.; Zajczyk, A.; Zdziarski, A. A.; Zech, A.; Zechlin, H.-S.

    2014-06-01

    The non-thermal nature of the X-ray emission from the shell-type supernova remnants (SNRs) G1.9+0.3 and G330.2+1.0 is an indication of intense particle acceleration in the shock fronts of both objects. This suggests that the SNRs are prime candidates for very-high-energy (VHE; E > 0.1 TeV) γ-ray observations. G1.9+0.3, recently established as the youngest known SNR in the Galaxy, also offers a unique opportunity to study the earliest stages of SNR evolution in the VHE domain. The purpose of this work is to probe the level of VHE γ-ray emission from both SNRs and use this to constrain their physical properties. Observations were conducted with the H.E.S.S. (High Energy Stereoscopic System) Cherenkov Telescope Array over a more than six-year period spanning 2004-2010. The obtained data have effective livetimes of 67 h for G1.9+0.3 and 16 h for G330.2+1.0. The data are analysed in the context of the multiwavelength observations currently available and in the framework of both leptonic and hadronic particle acceleration scenarios. No significant γ-ray signal from G1.9+0.3 or G330.2+1.0 was detected. Upper limits (99 per cent confidence level) to the TeV flux from G1.9+0.3 and G330.2+1.0 for the assumed spectral index Γ = 2.5 were set at 5.6 × 10-13 cm-2 s-1 above 0.26 TeV and 3.2 × 10-12 cm-2 s-1 above 0.38 TeV, respectively. In a one-zone leptonic scenario, these upper limits imply lower limits on the interior magnetic field to BG1.9 ≳ 12 μG for G1.9+0.3 and to BG330 ≳ 8 μG for G330.2+1.0. In a hadronic scenario, the low ambient densities and the large distances to the SNRs result in very low predicted fluxes, for which the H.E.S.S. upper limits are not constraining.

  13. HIV-1 Vif promotes the formation of high molecular mass APOBEC3G complexes

    OpenAIRE

    Goila-Gaur, Ritu; Khan, Mohammad A.; Miyagi, Eri; Kao, Sandra; Opi, Sandrine; Takeuchi, Hiroaki; Strebel, Klaus

    2007-01-01

    HIV-1 Vif inhibits the antiviral activity of APOBEC3G (APO3G) by inducing proteasomal degradation. Here, we studied the effects of Vif on APO3G in vitro. In this system, Vif did not cause APO3G degradation. Instead, Vif induced changes in APO3G that affected immunoprecipitation of the native protein. This effect required wt Vif and was reversed by heat-denaturation of APO3G. Sucrose gradient analysis demonstrated that wt Vif induced the gradual transition of APO3G translated in vitro or expre...

  14. Potential energy and dipole moment surfaces of the triplet states of the O2(X3Σg-) - O2(X3Σg-,a1Δg,b1Σg+) complex.

    Science.gov (United States)

    Karman, Tijs; van der Avoird, Ad; Groenenboom, Gerrit C

    2017-08-28

    We compute four-dimensional diabatic potential energy surfaces and transition dipole moment surfaces of O 2 -O 2 , relevant for the theoretical description of collision-induced absorption in the forbidden X 3 Σ g -  → a 1 Δ g and X 3 Σ g -  → b 1 Σ g + bands at 7883 cm -1 and 13 122 cm -1 , respectively. We compute potentials at the multi-reference configuration interaction (MRCI) level and dipole surfaces at the MRCI and complete active space self-consistent field (CASSCF) levels of theory. Potentials and dipole surfaces are transformed to a diabatic basis using a recent multiple-property-based diabatization algorithm. We discuss the angular expansion of these surfaces, derive the symmetry constraints on the expansion coefficients, and present working equations for determining the expansion coefficients by numerical integration over the angles. We also present an interpolation scheme with exponential extrapolation to both short and large separations, which is used for representing the O 2 -O 2 distance dependence of the angular expansion coefficients. For the triplet ground state of the complex, the potential energy surface is in reasonable agreement with previous calculations, whereas global excited state potentials are reported here for the first time. The transition dipole moment surfaces are strongly dependent on the level of theory at which they are calculated, as is also shown here by benchmark calculations at high symmetry geometries. Therefore, ab initio calculations of the collision-induced absorption spectra cannot become quantitatively predictive unless more accurate transition dipole surfaces can be computed. This is left as an open question for method development in electronic structure theory. The calculated potential energy and transition dipole moment surfaces are employed in quantum dynamical calculations of collision-induced absorption spectra reported in Paper II [T. Karman et al., J. Chem. Phys. 147, 084307 (2017)].

  15. Effect of pre-harvest fruit bagging on post-harvest quality of guava cv. Swarupkathi

    Directory of Open Access Journals (Sweden)

    Md. Mokter Hossain

    2018-04-01

    The investigation was carried out at Germplasm Centre (BAU-GPC, Bangladesh Agricultural University, during March to July 2016 in order to investigate the effect of pre-harvest fruit bagging on post-harvest quality of guava cv. Swarupkathi. Four different bagging materials viz. brown paper bag, white paper bag, white polythene bag, black polythene bag included for the study and uncovered fruits were used as control treatment. The experiment was laid out in randomized complete block design with three replications. Fruit bagging treatments showed significant effects on different parameters studied. It was observed that fruit size, fruit weight, vitamin C concentration, and moisture content increased due to fruit bagging. Fruits were gained maximum in size (6.59 cm length, 5.86 cm diameter and weight (164.26 g under white paper bag followed by white polythene bag (131.3g. The skin color of fruits was very attractive in case of white paper bag than that of other treatments. Total soluble solid concentration of the fruit was found maximum (12.33% Brix under brown paper bag while maximum vitamin C concentration (162.14 mg 100 g-1 was recorded under white paper bag. Uncovered fruits showed maximum total sugar, non-reducing sugar, reducing sugar concentrations (10.13%, 6.05%, 4.08%, respectively.The results revealed that fruit bagging in general, improved the growth and quality of guava fruits as compared to control. Among the various fruit covering materials, white paper bag was found to be the best for overall improvement of physical and chemical quality of guava cv. Swarupkathi. [Fundam Appl Agric 2018; 3(1.000: 363-371

  16. IJ-OpenCV: Combining ImageJ and OpenCV for processing images in biomedicine.

    Science.gov (United States)

    Domínguez, César; Heras, Jónathan; Pascual, Vico

    2017-05-01

    The effective processing of biomedical images usually requires the interoperability of diverse software tools that have different aims but are complementary. The goal of this work is to develop a bridge to connect two of those tools: ImageJ, a program for image analysis in life sciences, and OpenCV, a computer vision and machine learning library. Based on a thorough analysis of ImageJ and OpenCV, we detected the features of these systems that could be enhanced, and developed a library to combine both tools, taking advantage of the strengths of each system. The library was implemented on top of the SciJava converter framework. We also provide a methodology to use this library. We have developed the publicly available library IJ-OpenCV that can be employed to create applications combining features from both ImageJ and OpenCV. From the perspective of ImageJ developers, they can use IJ-OpenCV to easily create plugins that use any functionality provided by the OpenCV library and explore different alternatives. From the perspective of OpenCV developers, this library provides a link to the ImageJ graphical user interface and all its features to handle regions of interest. The IJ-OpenCV library bridges the gap between ImageJ and OpenCV, allowing the connection and the cooperation of these two systems. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. VizieR Online Data Catalog: Dwarf novae outbursts properties (Otulakowska-Hypka+, 2016)

    Science.gov (United States)

    Otulakowska-Hypka, M.; Olech, A.; Patterson, J.

    2017-11-01

    In this study, we used the following available catalogue data sources. The catalogue and atlas of CVs (https://archive.stsci.edu/prepds/cvcat/) by Downes et al. (2001PASP..113..764D, Cat. V/123) which contains 1830 objects that have been classified as a CV before 2006 February 1, when the catalogue was frozen. Catalogue of cataclysmic binaries, low-mass X-ray binaries and related objects (http://www.mpa-garching.mpg.de/RKcat/) by Ritter & Kolb (2003A&A...404..301R, Cat. B/cb). Although the reference corresponds to a catalogue which is over 10yr old, its newest edition 7.21 (2013 December 31) has been used in this study. This catalogue contains 1094 CVs. Catalogue of J. Patterson, that is the supplementary electronic material to the publication Patterson (2011) containing properties of 292 non-magnetic CVs with orbital periods smaller than 3h (http://cbastro.org/dwarfnovashort/) (1 data file).

  18. A 'new generation' earthquake catalogue

    Directory of Open Access Journals (Sweden)

    E. Boschi

    2000-06-01

    Full Text Available In 1995, we published the first release of the Catalogo dei Forti Terremoti in Italia, 461 a.C. - 1980, in Italian (Boschi et al., 1995. Two years later this was followed by a second release, again in Italian, that included more earthquakes, more accurate research and a longer time span (461 B.C. to 1990 (Boschi et al., 1997. Aware that the record of Italian historical seismicity is probably the most extensive of the whole world, and hence that our catalogue could be of interest for a wider interna-tional readership, Italian was clearly not the appropriate language to share this experience with colleagues from foreign countries. Three years after publication of the second release therefore, and after much additional research and fine tuning of methodologies and algorithms, I am proud to introduce this third release in English. All the tools and accessories have been translated along with the texts describing the development of the underlying research strategies and current contents. The English title is Catalogue of Strong Italian Earthquakes, 461 B.C. to 1997. This Preface briefly describes the scientific context within which the Catalogue of Strong Italian Earthquakes was conceived and progressively developed. The catalogue is perhaps the most impor-tant outcome of a well-established joint project between the Istituto Nazionale di Geofisica, the leading Italian institute for basic and applied research in seismology and solid earth geophysics, and SGA (Storia Geofisica Ambiente, a private firm specialising in the historical investigation and systematisation of natural phenomena. In her contribution "Method of investigation, typology and taxonomy of the basic data: navigating between seismic effects and historical contexts", Emanuela Guidoboni outlines the general framework of modern historical seismology, its complex relation with instrumental seismology on the one hand and historical research on the other. This presentation also highlights

  19. A Study of Equipment Accuracy and Test Precision in Dual Energy X-ray Absorptiometry

    International Nuclear Information System (INIS)

    Dong, Kyung Rae; Kim, Ho Sung; Jung, Woon Kwan

    2008-01-01

    Because there is a difference depending on the environment as for an inspection equipment the important part of bone density scan and the precision/accuracy of a tester, the management of quality must be made systematically. The equipment failure caused by overload effect due to the aged equipment and the increase of a patient was made frequently. Thus, the replacement of equipment and additional purchases of new bone density equipment caused a compatibility problem in tracking patients. This study wants to know whether the clinical changes of patient's bone density can be accurately and precisely reflected when used it compatibility like the existing equipment after equipment replacement and expansion. Two equipment of GE Lunar Prodigy Advance(P1 and P2) and the Phantom HOLOGIC Spine Road(HSP) were used to measure equipment precision. Each device scans 20 times so that precision data was acquired from the phantom(Group 1). The precision of a tester was measured by shooting twice the same patient, every 15 members from each of the target equipment in 120 women(average age 48.78, 20-60 years old)(Group 2). In addition, the measurement of the precision of a tester and the cross-calibration data were made by scanning 20 times in each of the equipment using HSP, based on the data obtained from the management of quality using phantom(ASP) every morning (Group 3). The same patient was shot only once in one equipment alternately to make the measurement of the precision of a tester and the cross-calibration data in 120 women(average age 48.78, 20-60 years old)(Group 4). It is steady equipment according to daily Q.C Data with 0.996 g/cm 2 , change value(%CV) 0.08. The meanSD and a %CV price are ALP in Group 1(P1 : , , P2 : , %CV=0.192). The mean±SD and a %CV price are P1 : 1.064±0.002 g/cm 2 , %CV=0.190 g/cm 2 , P2 : 1.061±0.003 g/cm 3 , %CV=0.163 in Group 2. The average error±2SD and %CV are P1 - (spine: 0.001±0.013 g/cm 2 , %CV=0.94, Femur: 0.001±0.019 g/cm 2 , %CV

  20. A Study of Equipment Accuracy and Test Precision in Dual Energy X-ray Absorptiometry

    Energy Technology Data Exchange (ETDEWEB)

    Dong, Kyung Rae [Dept. of Radiological Technology, Gwangju Health College, Gwangju (Korea, Republic of); Kim, Ho Sung [Dept. of Nuclear Medicine, Asan Medical Center, Seoul (Korea, Republic of); Jung, Woon Kwan [Dept. of Nuclear Energy Technology, Chosun University, Gwangju (Korea, Republic of)

    2008-03-15

    Because there is a difference depending on the environment as for an inspection equipment the important part of bone density scan and the precision/accuracy of a tester, the management of quality must be made systematically. The equipment failure caused by overload effect due to the aged equipment and the increase of a patient was made frequently. Thus, the replacement of equipment and additional purchases of new bone density equipment caused a compatibility problem in tracking patients. This study wants to know whether the clinical changes of patient's bone density can be accurately and precisely reflected when used it compatibility like the existing equipment after equipment replacement and expansion. Two equipment of GE Lunar Prodigy Advance(P1 and P2) and the Phantom HOLOGIC Spine Road(HSP) were used to measure equipment precision. Each device scans 20 times so that precision data was acquired from the phantom(Group 1). The precision of a tester was measured by shooting twice the same patient, every 15 members from each of the target equipment in 120 women(average age 48.78, 20-60 years old)(Group 2). In addition, the measurement of the precision of a tester and the cross-calibration data were made by scanning 20 times in each of the equipment using HSP, based on the data obtained from the management of quality using phantom(ASP) every morning (Group 3). The same patient was shot only once in one equipment alternately to make the measurement of the precision of a tester and the cross-calibration data in 120 women(average age 48.78, 20-60 years old)(Group 4). It is steady equipment according to daily Q.C Data with 0.996 g/cm{sup 2}, change value(%CV) 0.08. The meanSD and a %CV price are ALP in Group 1(P1 : , , P2 : , %CV=0.192). The mean{+-}SD and a %CV price are P1 : 1.064{+-}0.002 g/cm{sup 2}, %CV=0.190 g/cm{sup 2}, P2 : 1.061{+-}0.003 g/cm{sup 3}, %CV=0.163 in Group 2. The average error{+-}2SD and %CV are P1 - (spine: 0.001{+-}0.013 g/cm{sup 2}, %CV=0

  1. A catalogue of crude oil and oil product properties, 1990

    International Nuclear Information System (INIS)

    Bobra, M.A.; Callaghan, S.

    1990-09-01

    This catalogue is a compilation of available data on crude oils and petroleum products. The emphasis of the catalogue is upon oils which could potentially impact Canada's environment. Other oils which are unlikely to be of direct Canadian concern are also included because they have been well characterized and used in relevant studies. The properties listed for each oil are those which will provide an indication of a spilled oil's environmental behaviour and effects. The properties on which data is provided include API gravity, density, viscosity, interfacial tension, pour point, flash point, vapor pressure, volatility and component distribution, emulsion formation tendency and stability, weathering, dispersability, major hydrocarbon groups, aqueous solubility, toxicity, sulfur content, fire point, and wax content. Most of the chemical-physical properties listed in this catalogue were measured using standard tests. For certain properties, data are given at different temperatures and for different degrees of oil weathering. An oil's degree of weathering is expresed as the volume or weight percent evaporated from the fresh oil. Weathered oils used for testing were artificially weathered by gas stripping following the method of Mackay and Stiver. 109 refs

  2. A catalogue of crude oil and oil product properties, 1992

    International Nuclear Information System (INIS)

    Whiticar, S.; Bobra, M.; Liuzzo, P.; Callaghan, S.; Fingas, M.; Jokuty, P.; Ackerman, F.; Cao, J.

    1993-02-01

    This catalogue is a compilation of available data on crude oils and petroleum products. The emphasis of the catalogue is upon oils which could potentially impact Canada's environment. Other oils which are unlikely to be of direct Canadian concern are also included because they have been well characterized and used in relevant studies. The properties listed for each oil are those which will provide an indication of a spilled oil's environmental behaviour and effects. The properties on which data is provided include API gravity, density, viscosity, interfacial tension, pour point, flash point, vapor pressure, volatility and component distribution, emulsion formation tendency and stability, weathering, dispersability, major hydrocarbon groups, aqueous solubility, toxicity, sulfur content, fire point, and wax content. Most of the chemical-physical properties listed in this catalogue were measured using standard tests. For certain properties, data are given at different temperatures and for different degrees of oil weathering. An oil's degree of weathering is expresed as the volume or weight percent evaporated from the fresh oil. Weathered oils used for testing were artificially weathered by gas stripping following the method of Mackay and Stiver. 140 refs

  3. Multi-Shock Shield Performance at 15 MJ for Catalogued Debris

    Science.gov (United States)

    Miller, J. E.; Davis, B. A.; Christiansen, E. L.; Lear, D. M.

    2015-01-01

    While orbital debris of ten centimeters or more are tracked and catalogued, the difficulty of finding and accurately accounting for forces acting on the objects near the ten centimeter threshold results in both uncertainty of their presence and location. These challenges result in difficult decisions for operators balancing potential costly operational approaches with system loss risk. In this paper, the assessment of the feasibility of protecting a spacecraft from this catalogued debris is described using numerical simulations and a test of a multi-shock shield system against a cylindrical projectile impacting normal to the surface with approximately 15 MJ of kinetic energy. The hypervelocity impact test has been conducted at the Arnold Engineering Development Complex (AEDC) with a 598 g projectile at 6.905 km/s on a NASA supplied multi-shock shield. The projectile used is a hollow aluminum and nylon cylinder with an outside diameter of 8.6 cm and length of 10.3 cm. Figure 1 illustrates the multi-shock shield test article, which consisted of five separate bumpers, four of which are fiberglass fabric and one of steel mesh, and two rear walls, each consisting of Kevlar fabric. The overall length of the test article was 2.65 m. The test article was a 5X scaled-up version of a smaller multi-shock shield previously tested using a 1.4 cm diameter aluminum projectile for an inflatable module project. The distances represented by S1 and S1/2 in the figure are 61 cm and 30.5 cm, respectively. Prior to the impact test, hydrodynamic simulations indicated that some enhancement to the standard multi-shock system is needed to address the effects of the cylindrical shape of the projectile. Based on the simulations, a steel mesh bumper has been added to the shield configuration to enhance the fragmentation of the projectile. The AEDC test occurred as planned, and the modified NASA multi-shock shield successfully stopped 598 g projectile using 85.6 kg/m(exp 2). The fifth bumper

  4. The AKARI IRC asteroid flux catalogue: updated diameters and albedos

    Science.gov (United States)

    Alí-Lagoa, V.; Müller, T. G.; Usui, F.; Hasegawa, S.

    2018-05-01

    The AKARI IRC all-sky survey provided more than twenty thousand thermal infrared observations of over five thousand asteroids. Diameters and albedos were obtained by fitting an empirically calibrated version of the standard thermal model to these data. After the publication of the flux catalogue in October 2016, our aim here is to present the AKARI IRC all-sky survey data and discuss valuable scientific applications in the field of small body physical properties studies. As an example, we update the catalogue of asteroid diameters and albedos based on AKARI using the near-Earth asteroid thermal model (NEATM). We fit the NEATM to derive asteroid diameters and, whenever possible, infrared beaming parameters. We fit groups of observations taken for the same object at different epochs of the survey separately, so we compute more than one diameter for approximately half of the catalogue. We obtained a total of 8097 diameters and albedos for 5170 asteroids, and we fitted the beaming parameter for almost two thousand of them. When it was not possible to fit the beaming parameter, we used a straight line fit to our sample's beaming parameter-versus-phase angle plot to set the default value for each fit individually instead of using a single average value. Our diameters agree with stellar-occultation-based diameters well within the accuracy expected for the model. They also match the previous AKARI-based catalogue at phase angles lower than 50°, but we find a systematic deviation at higher phase angles, at which near-Earth and Mars-crossing asteroids were observed. The AKARI IRC All-sky survey is an essential source of information about asteroids, especially the large ones, since, it provides observations at different observation geometries, rotational coverages and aspect angles. For example, by comparing in more detail a few asteroids for which dimensions were derived from occultations, we discuss how the multiple observations per object may already provide three

  5. Supersymmetric M3-branes and G{sub 2} manifolds

    Energy Technology Data Exchange (ETDEWEB)

    Cvetic, M. E-mail: cvetic@cvetic.hep.upenn.edu; Gibbons, G.W.; Lue, H.; Pope, C.N

    2002-01-07

    We obtain a generalisation of the original complete Ricci-flat metric of G{sub 2} holonomy on R{sup 4}xS{sup 3} to a family with a nontrivial parameter {lambda}. For generic {lambda} the solution is singular, but it is regular when {lambda}={l_brace}-1,0,+1{r_brace}. The case {lambda}=0 corresponds to the original G{sub 2} metric, and {lambda}={l_brace}-1,1{r_brace} are related to this by an S{sub 3} automorphism of the SU(2){sup 3} isometry group that acts on the S{sup 3}xS{sup 3} principal orbits. We then construct explicit supersymmetric M3-brane solutions in D=11 supergravity, where the transverse space is a deformation of this class of G{sub 2} metrics. These are solutions of a system of first-order differential equations coming from a superpotential. We also find M3-branes in the deformed backgrounds of new G{sub 2} holonomy metrics that include one found by A. Brandhuber, J. Gomis, S. Gubser and S. Gukov, and show that they also are supersymmetric.

  6. Publications catalogue 1982-83

    International Nuclear Information System (INIS)

    1982-04-01

    This catalogue lists the technical reports, papers, speeches, regulatory documents, news releases, information bulletins, notices, and miscellaneous documents issued by the Canadian Atomic Energy Control Board between 1977 and 1982

  7. Wilting and biological additive effect on in situ degradability and chemical composition of Arachis pintoi cv Belomonte silage

    OpenAIRE

    Rosana Aparecida Possenti; Evaldo Ferrari Júnior; Valdinei Tadeu Paulino; Ivani Pozar Otsuk; Patrícia Brás

    2010-01-01

    The purpose of this work was to evaluate the effect of wilting and biological additive amendment on chemical composition, fermentation and ruminal degradability of Arachis pintoi cv Belmonte silage. The following treatments were analysed: T1- Arachis pintoi cv Belmonte fresh forage; T2 - Arachis pintoi cv Belmonte fresh forage plus bacterial additive added to the forage prior to the ensilage; T3- Arachis pintoi cv Belmonte wilted by the sun for 4 hours; T4- Arachis pintoi cv Belmonte wilted b...

  8. Planck 2013 results. XXVIII. The Planck Catalogue of Compact Sources

    DEFF Research Database (Denmark)

    Planck Collaboration,; Ade, P. A. R.; Aghanim, N.

    2013-01-01

    The Planck Catalogue of Compact Sources (PCCS) is the catalogue of sources detected in the Planck nominal mission data. It consists of nine single-frequency catalogues of compact sources containing reliable sources, both Galactic and extragalactic, detected over the entire sky. The PCCS covers th...

  9. CHALLENGES AND OPPORTUNITIES OF CATALOGUE RETAILING

    OpenAIRE

    Heri Bezic; Katija Vojvodic; Zrinka Gjanovic

    2012-01-01

    Today`s retail environment is characterised by new, store and non-store, retailing formats, a wide range of new products, the use of new information and communication technologies and, consequently, the changing customer behaviour. Catalogue retailing is a non-store retail format that has a long history in North America and Europe. Previous research revealed that the primary shopping motives related to catalogue retailing were convenience oriented. Other motives included recreational orientat...

  10. Fc-Glycosylation in Human IgG1 and IgG3 Is Similar for Both Total and Anti-Red-Blood Cell Anti-K Antibodies

    Directory of Open Access Journals (Sweden)

    Myrthe E. Sonneveld

    2018-01-01

    Full Text Available After albumin, immunoglobulin G (IgG are the most abundant proteins in human serum, with IgG1 and IgG3 being the most abundant subclasses directed against protein antigens. The quality of the IgG-Fc-glycosylation has important functional consequences, which have been found to be skewed toward low fucosylation in some antigen-specific immune responses. This increases the affinity to IgG1-Fc-receptor (FcγRIIIa/b and thereby directly affects downstream effector functions and disease severity. To date, antigen-specific IgG-glycosylation have not been analyzed for IgG3. Here, we analyzed 30 pregnant women with anti-K alloantibodies from a prospective screening cohort and compared the type of Fc-tail glycosylation of total serum- and antigen-specific IgG1 and IgG3 using mass spectrometry. Total serum IgG1 and IgG3 Fc-glycoprofiles were highly similar. Fc glycosylation of antigen-specific IgG varied greatly between individuals, but correlated significantly with each other for IgG1 and IgG3, except for bisection. However, although the magnitude of changes in fucosylation and galactosylation were similar for both subclasses, this was not the case for sialylation levels, which were significantly higher for both total and anti-K IgG3. We found that the combination of relative IgG1 and IgG3 Fc-glycosylation levels did not improve the prediction of anti-K mediated disease over IgG1 alone. In conclusion, Fc-glycosylation profiles of serum- and antigen-specific IgG1 and IgG3 are highly similar.

  11. CV controls from design to operation

    CERN Document Server

    Blanc, D

    2002-01-01

    The cooling and Ventilation (CV) group has emphasised the need to redefine its organisational structure at the end of 98. The main objective of this operation was to ensure the CV group to be more competitive and efficient through the growing tasks of the LHC projects. The main evolution given to this reorganisation is that the new structure is more project oriented and then operates on three distinct axes: Design, Work and Operation. Process control project management requires a complete and early interaction and participation of all the actors involved. This procedure to be efficient and constructive must be considered and performed not only during the design stage but along the project planning phases and must go beyond the completion work including the process control operation activity. The paper explains the present project management for process control. It describes the present constraints and gives suggestions to a different approach to these projects to improve performances and efficiency of a contr...

  12. Anticipatory grip force between 1 and 3g

    Science.gov (United States)

    White, Olivier; Van Loon, ing.. Jack J. W. A.; Thonnard, Jean-Louis; Hermsdorfer, Joachim; Lefevre, Philippe

    One remarkable capacity of utilizing common tools appropriately as soon as we grasp them relies on the ability to determine in advance the grip force (GF) required to handle them in relation to their mechanical properties and the surrounding environment. This anticipatory strategy avoids the uncompressible delays in the feedback system. The predictive control of GF is made possible because the nervous system can learn, store and then select the internal representations of the dynamics of innumerable objects, known as internal models. Beside this flexibility, the nervous system's ability to learn different task dynamics is often limited in classical robotic experiments The environment itself can be profoundly modified in altered gravity or centrifugation. The few studies that investigated motor adaptation in such contexts did not consider the interaction between gravitational phases and even less the transitions across environments. Here, we tested subject's abilities to adapt to levels of gravitational fields generated by a human centrifuge. In Experiment 1, seven subjects performed 4 lifting trials in each gravitational phase (1 to 2.5g and then 2.5 to 1g by steps of 0.5g) with a 0.12 kg instrumented object. In Experiment 2, six subjects performed vertical oscillations of the object during transitions between 1 and 3g (0.5g steps, ascending and descending phases, profile repeated twice). We continuously measured GF, load force (LF) and ambient gravity. We hypothesized that participants were able to predictively adjust GF to the new environment. In Experiment 1, participants adjusted their GF proportionally to gravity and decreased GF across trials within a given gravitational environment. Preload phases decreased over time from 300ms to 50ms irrespective of gravity. We quantified the abilities of participants to switch across environments by subtracting GF recorded in the last trial in the current gravity level from GF during the first trial in the new environment

  13. Seismological database for Banat seismic region (Romania) - Part 1: The parametric earthquake catalogue

    International Nuclear Information System (INIS)

    Oros, E.; Popa, M.; Moldovan, I. A.

    2008-01-01

    The most comprehensive seismological database for Banat seismic region (Romania) has been achieved. This paper refers to the essential characteristics of the first component of this database, namely the Parametric Earthquakes Catalogue for the Banat Seismic Region (PECBSR). PECBSR comprises 7783 crustal earthquakes (3 ≤ h ≤ 25 km) with 0.4 ≤ M i ≥ 5.6 (M i is M L , M D , M S , M W , Mm and/or mb from compiled sources) occurred in the Banat region and its surroundings between years 1443 and 2006. Different magnitude scales were converted into moment magnitude scale, Mw. The completeness of PECBSR strongly depends on the time. (authors)

  14. 3:1 compression to ventilation ratio versus continuous chest compression with asynchronous ventilation in a porcine model of neonatal resuscitation.

    Science.gov (United States)

    Schmölzer, Georg M; O'Reilly, Megan; Labossiere, Joseph; Lee, Tze-Fun; Cowan, Shaun; Nicoll, Jessica; Bigam, David L; Cheung, Po-Yin

    2014-02-01

    In contrast to the resuscitation guidelines of children and adults, guidelines on neonatal resuscitation recommend synchronized 90 chest compressions with 30 manual inflations (3:1) per minute in newborn infants. The study aimed to determine if chest compression with asynchronous ventilation improves the recovery of bradycardic asphyxiated newborn piglets compared to 3:1 Compression:Ventilation cardiopulmonary resuscitation (CPR). Term newborn piglets (n=8/group) were anesthetized, intubated, instrumented and exposed to 45-min normocapnic hypoxia followed by asphyxia. Protocolized resuscitation was initiated when heart rate decreased to 25% of baseline. Piglets were randomized to receive resuscitation with either 3:1 compressions to ventilations (3:1C:V CPR group) or chest compressions with asynchronous ventilations (CCaV) or sham. Continuous respiratory parameters (Respironics NM3(®)), cardiac output, mean systemic and pulmonary artery pressures, and regional blood flows were measured. Piglets in 3:1C:V CPR and CCaV CPR groups had similar time to return of spontaneous circulation, survival rates, hemodynamic and respiratory parameters during CPR. The systemic and regional hemodynamic recovery in the subsequent 4h was similar in both groups and significantly lower compared to sham-operated piglets. Newborn piglets resuscitated by CCaV had similar return of spontaneous circulation, survival, and hemodynamic recovery compared to those piglets resuscitated by 3:1 Compression:Ventilation ratio. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  15. G2 and G3 reactors design; Description des reacteurs G2 et G3

    Energy Technology Data Exchange (ETDEWEB)

    Herreng,; Ertaud,; Pasquet, [Societe Alsacienne de Constructions Mecaniques (France)

    1958-07-01

    'FRANCE ATOME' Manufacturers Party has been entrusted with the G2 and G3 reactors engineering by the french A.E.C., for the first-five-year french project. Although these reactors are essentially plutonium generators, everyone has been linked with a power station which is supposed to supply with 40 MW, 'Electricite de France' has taken the liability upon itself. The reactor core includes most of G1 reactor parts (central gap excluded): horizontal channels, graphite parallelepipedic bricks stacking, steel thermal shield. The cooling is provided with CO{sub 2} under a 15 atmospheres pressure. This pressure is kept steady in a press-stressed concrete packing-case which is a cylinder horizontally shaped. Steel strips tightened encircle the concrete cylinder; itself protected by sole-plates. The cylinder bottom has brought about unusual problems which have been solved by the choice of an hemispheric shape. Packing-case tightness is provided by a 30 mm iron-plate connected with the inner wall of concrete. One of the reactor's special characteristics is the possibility of loading and unloading while operating. On loading side, barrel locks, each weighting 50 tons, allow new cans, at a pressure of 15 atmospheres, to pass. The cans process almost in a steady way through the channel, and finally drop down through bent spouts, then through spiral toboggans into a new lock. The cooling CO{sub 2} flow is provided with 3 turbo-bellows, these are actuated by average pressure-steam, obtained from exchangers. Every reactor supplies 4 exchangers which have been very difficult to build and to set up. The secondary cycle is standard and contains 3 stages (pressure 10,3: 2 and 0,5 kg/cm{sup 2}). Steam can be condensed in the event of a group turbo-generator stopping, with no modifion for the normal operating conditions of the reactor. Auxiliary circuits have to assure the continuous purifying of cooling CO{sub 2}, its storage and drain. 49 boron carbide rods are used to control the

  16. Reactions of small negative ions with O2(a 1[Delta]g) and O2(X 3[Sigma]g-)

    Science.gov (United States)

    Midey, Anthony; Dotan, Itzhak; Seeley, J. V.; Viggiano, A. A.

    2009-02-01

    The rate constants and product ion branching ratios were measured for the reactions of various small negative ions with O2(X 3[Sigma]g-) and O2(a 1[Delta]g) in a selected ion flow tube (SIFT). Only NH2- and CH3O- were found to react with O2(X) and both reactions were slow. CH3O- reacted by hydride transfer, both with and without electron detachment. NH2- formed both OH-, as observed previously, and O2-, the latter via endothermic charge transfer. A temperature study revealed a negative temperature dependence for the former channel and Arrhenius behavior for the endothermic channel, resulting in an overall rate constant with a minimum at 500 K. SF6-, SF4-, SO3- and CO3- were found to react with O2(a 1[Delta]g) with rate constants less than 10-11 cm3 s-1. NH2- reacted rapidly with O2(a 1[Delta]g) by charge transfer. The reactions of HO2- and SO2- proceeded moderately with competition between Penning detachment and charge transfer. SO2- produced a SO4- cluster product in 2% of reactions and HO2- produced O3- in 13% of the reactions. CH3O- proceeded essentially at the collision rate by hydride transfer, again both with and without electron detachment. These results show that charge transfer to O2(a 1[Delta]g) occurs readily if the there are no restrictions on the ion beyond the reaction thermodynamics. The SO2- and HO2- reactions with O2(a) are the only known reactions involving Penning detachment besides the reaction with O2- studied previously [R.S. Berry, Phys. Chem. Chem. Phys., 7 (2005) 289-290].

  17. The European Large-Area ISO Survey (ELAIS): the final band-merged catalogue

    DEFF Research Database (Denmark)

    Rowan-Robinson, M.; Lari, C.; Perez-Fournon, I.

    2004-01-01

    We present the final band-merged European Large-Area ISO Survey (ELAIS) Catalogue at 6.7, 15, 90 and 175 mum, and the associated data at U, g', r', i', Z, J, H, K and 20 cm. The origin of the survey, infrared and radio observations, data-reduction and optical identifications are briefly reviewed...

  18. VizieR Online Data Catalog: XMM-Newton slew survey Source Catalogue, version 2.0 (XMM-SSC, 2017)

    Science.gov (United States)

    XMM-SSC

    2018-01-01

    XMMSL2 is the second catalogue of X-ray sources found in slew data taken from the European Space Agency's (ESA) XMM-Newton observatory, and has been constructed by members of the XMM SOC and the EPIC consortium on behalf of ESA. This release uses results of work which has been carried out within the framework of the EXTraS project ("Exploring the X-ray variable and Transient Sky"), funded from the EU's Seventh Framework Programme under grant agreement no.607452. This is the first release of XMMSL2 which contains data taken between revolutions 314 and 2758. The previous catalogue was called XMMSL1_Delta6 and contained slews up to revolution 2441. The release includes two FITS files. A full catalogue (xmmsl2_total.fits.gz), containing 72352 detections found with a likelihood of DETML>8 and a "clean" catalogue (xmmsl2clean.fits.gz) where all known bad sources have been removed and where the detection limit has been raised to DETML>10.5 in general and DETML>15.5 for sources found in images with a higher than usual background. Efforts have been made to identify spurious detections and 3017 have been flagged as such in the full catalogue. (3 data files).

  19. Matilda, where are you: subject description of juvenile fiction in the Slovenian catalogue and catalogues of neighbouring countries

    Directory of Open Access Journals (Sweden)

    Alenka Šauperl

    2009-01-01

    Full Text Available Differences in subject description of juvenile fiction was investigated on five examples of international classics in five library catalogues: Oton Župančič Public Library (Knjižnica Otona Župančiča in Ljubljana, Slovenia, Stadtbibliothek public library in Graz, Austria, integrated catalogues of libraries in the Gorizia region in Italy (Sistema bibliotecario della Provincia di Gorizia and the Karlovac region in Croatia (Skupni katalog knjižnica Karlovačke županije in September 2008. As Slovenian youth rarely speaks languages of neighbouring countries, British Library catalogue was added.Results show that catalogue records are inconsistent within an individual library as well as in comparision with other libraries in the sample. Librarians do not make consistent subject descriptions. Class number, which is present in all catalogues except in the Austrian one, usually represents: the author’s country, language and/or nationality,the literary genre, and the target audience.Subject headings in the sample bring information on the subject (aboutness, author’s country, language and/or nationality, the literary genre, and target audience. Summaries tell more on the story. But they can also bring information on emotional experience of the reader, information on the author or history of the literary work. It would be economically beneficial if subject description could be more consistent. But uniform subject description is not possible because of diverse library collections and users.The solution might be in the use of multiple levels of subject description regarding to the type of the libraries.

  20. The Raincoast eCatalogue: the creation of an electronic catalogue as a supplemental selling tool for sales representatives

    OpenAIRE

    Kemp, Elizabeth Anne

    2011-01-01

    Raincoast Books Distribution Ltd. is a Canadian book distributor that provides sales, marketing and distribution services for a number of international and Canadian publishers. Each publishing season Raincoast Books distributes approximately 25,000 paper catalogues to sales representatives and retail accounts. Traditional paper catalogues have major disadvantages including their static format, high cost of production and distribution, inclusion of frontlist titles only and environmental impac...

  1. Relationship between post-SARS osteonecrosis and PAI-1 4G/5G gene polymorphisms.

    Science.gov (United States)

    Sun, Wei; Li, Zirong; Shi, Zhengcai; Wang, Bailiang; Gao, Fuqiang; Yang, Yurun; Guo, Wanshou

    2014-05-01

    To explore the correlation between post-severe acute respiratory symptom (SARS) patients with osteonecrosis, investigate the etiology of post-SARS osteonecrosis and select the sensitive molecular symbols for early diagnosis and distinguish the high-risk population. The studied subjects were divided into two groups. Sixty-two post-SARS patients with osteonecrosis were one group, and 52 age- and sex-matched healthy people were as normal controlled group. Empty stomach blood samples from cubital veins were collected from both groups. Plasminogen activator inhibitor (PAI) by means of enzyme-linked immunosorbent assay and PAI-1 4G/5G polymorphism was detected by polymerase chain reaction and solid phase oligonucleotide assay. The blood agents of post-SARS patients changed obviously with 15.64 ± 13.85 U/ml while the control group 7.96 ± 4.27 U/ml; 4G/4G genotype for the PAI-1 polymorphism detected in post-SARS group was more than that of the control group, but had no statistical significance. The plasma PAI activity was related to homozygote 4G/4G genotype. This reveals that homozygote 4G/4G genotype may be a susceptible gene mark to Chinese osteonecrosis patients. Plasminogen activator inhibitor-1 is sensitive blood symbol for screening high-risk susceptible population; 4G/4G PAI-1 genotype may be an etiological factor in osteonecrosis.

  2. The PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteins.

    Science.gov (United States)

    An, Ningfei; Blumer, Joe B; Bernard, Michael L; Lanier, Stephen M

    2008-09-05

    Activator of G-protein signaling 3 (AGS3) is one of nine mammalian proteins containing one or more G-protein regulatory (GPR) motifs that stabilize the GDP-bound conformation of Galphai. Such proteins have revealed unexpected functional diversity for the "G-switch" in the control of events within the cell independent of the role of heterotrimeric G-proteins as transducers for G-protein-coupled receptors at the cell surface. A key question regarding this class of proteins is what controls their subcellular positioning and interaction with G-proteins. We conducted a series of yeast two-hybrid screens to identify proteins interacting with the tetratricopeptide repeat (TPR) of AGS3, which plays an important role in subcellular positioning of the protein. We report the identification of Frmpd1 (FERM and PDZ domain containing 1) as a regulatory binding partner of AGS3. Frmpd1 binds to the TPR domain of AGS3 and coimmunoprecipitates with AGS3 from cell lysates. Cell fractionation indicated that Frmpd1 stabilizes AGS3 in a membrane fraction. Upon cotransfection of COS7 cells with Frmpd1-GFP and AGS3-mRFP, AGS3-mRFP is observed in regions of the cell cortex and also in membrane extensions or processes where it appears to be colocalized with Frmpd1-GFP based upon the merged fluorescent signals. Frmpd1 knockdown (siRNA) in Cath.a-differentiated neuronal cells decreased the level of endogenous AGS3 in membrane fractions by approximately 50% and enhanced the alpha2-adrenergic receptor-mediated inhibition of forskolin-induced increases in cAMP. The coimmunoprecipitation of Frmpd1 with AGS3 is lost as the amount of Galphai3 in the cell is increased and AGS3 apparently switches its binding partner from Frmpd1 to Galphai3 indicating that the interaction of AGS3 with Frmpd1 and Galphai3 is mutually exclusive. Mechanistically, Frmpd1 may position AGS3 in a membrane environment where it then interacts with Galphai in a regulated manner.

  3. An application of data mining techniques in designing catalogue for a laundry service

    Directory of Open Access Journals (Sweden)

    Khasanah Annisa Uswatun

    2018-01-01

    Full Text Available Catalogues are the media that companies use to promote their products or services. Since catalogue is one of marketing media, the first essential step before designing product catalogue is determining the market target. Besides, it is also important to put some information that appeal to the target market, such as discount or promos by analysing customer pattern preferences in using services or buying product. This study conduct two data mining technique. The first is clustering analysis to segment customer and the second one is association rule mining to discover an interesting pattern about the services that commonly used by the customer at the same service time. Thus, the results will be used as a recommendation to make an attractive marketing strategy to be put in the service catalogue promo for a laundry in Sleman Yogyakarta. The clustering result showed that the biggest customer segment is university student who come 3 until 5 times in a month on weekends, while the association rule result showed that clothes, shoes, and bed sheet have strong relationship. The catalogue design is presented in the end of the paper.

  4. Effects of 2G and 3G mobile phones on performance and electrophysiology in adolescents, young adults and older adults.

    Science.gov (United States)

    Leung, S; Croft, R J; McKenzie, R J; Iskra, S; Silber, B; Cooper, N R; O'Neill, B; Cropley, V; Diaz-Trujillo, A; Hamblin, D; Simpson, D

    2011-11-01

    This study examined sensory and cognitive processing in adolescents, young adults and older adults, when exposed to 2nd (2G) and 3rd (3G) generation mobile phone signals. Tests employed were the auditory 3-stimulus oddball and the N-back. Forty-one 13-15 year olds, forty-two 19-40 year olds and twenty 55-70 year olds were tested using a double-blind cross-over design, where each participant received Sham, 2G and 3G exposures, separated by at least 4 days. 3-Stimulus oddball task: Behavioural: accuracy and reaction time of responses to targets were not affected by exposure. Electrophysiological: augmented N1 was found in the 2G condition (independent of age group). N-back task: Behavioural: the combined groups performed less accurately during the 3G exposure (compared to Sham), with post hoc tests finding this effect separately in the adolescents only. Electrophysiological: delayed ERD/ERS responses of the alpha power were found in both 3G and 2G conditions (compared to Sham; independent of age group). Employing tasks tailored to each individual's ability level, this study provides support for an effect of acute 2G and 3G exposure on human cognitive function. The subtlety of mobile phone effect on cognition in our study suggests that it is important to account for individual differences in future mobile phone research. Copyright © 2011 International Federation of Clinical Neurophysiology. All rights reserved.

  5. Quantifying uncertainty in NDSHA estimates due to earthquake catalogue

    Science.gov (United States)

    Magrin, Andrea; Peresan, Antonella; Vaccari, Franco; Panza, Giuliano

    2014-05-01

    The procedure for the neo-deterministic seismic zoning, NDSHA, is based on the calculation of synthetic seismograms by the modal summation technique. This approach makes use of information about the space distribution of large magnitude earthquakes, which can be defined based on seismic history and seismotectonics, as well as incorporating information from a wide set of geological and geophysical data (e.g., morphostructural features and ongoing deformation processes identified by earth observations). Hence the method does not make use of attenuation models (GMPE), which may be unable to account for the complexity of the product between seismic source tensor and medium Green function and are often poorly constrained by the available observations. NDSHA defines the hazard from the envelope of the values of ground motion parameters determined considering a wide set of scenario earthquakes; accordingly, the simplest outcome of this method is a map where the maximum of a given seismic parameter is associated to each site. In NDSHA uncertainties are not statistically treated as in PSHA, where aleatory uncertainty is traditionally handled with probability density functions (e.g., for magnitude and distance random variables) and epistemic uncertainty is considered by applying logic trees that allow the use of alternative models and alternative parameter values of each model, but the treatment of uncertainties is performed by sensitivity analyses for key modelling parameters. To fix the uncertainty related to a particular input parameter is an important component of the procedure. The input parameters must account for the uncertainty in the prediction of fault radiation and in the use of Green functions for a given medium. A key parameter is the magnitude of sources used in the simulation that is based on catalogue informations, seismogenic zones and seismogenic nodes. Because the largest part of the existing catalogues is based on macroseismic intensity, a rough estimate

  6. VizieR Online Data Catalog: REFLEX Galaxy Cluster Survey catalogue (Boehringer+, 2004)

    Science.gov (United States)

    Boehringer, H.; Schuecker, P.; Guzzo, L.; Collins, C. A.; Voges, W.; Cruddace, R. G.; Ortiz-Gil, A.; Chincarini, G.; de Grandi, S.; Edge, A. C.; MacGillivray, H. T.; Neumann, D. M.; Schindler, S.; Shaver, P.

    2004-05-01

    The following tables provide the catalogue as well as several data files necessary to reproduce the sample preparation. These files are also required for the cosmological modeling of these observations in e.g. the study of the statistics of the large-scale structure of the matter distribution in the Universe and related cosmological tests. (13 data files).

  7. Differential contributions of ubiquitin-modified APOBEC3G lysine residues to HIV-1 Vif-induced degradation

    OpenAIRE

    Turner, Tiffany; Shao, Qiujia; Wang, Weiran; Wang, Yudi; Wang, Chenliang; Kinlock, Ballington; Liu, Bindong

    2016-01-01

    Apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (A3G) is a host restriction factor that impedes HIV-1 replication. Viral integrity is salvaged by HIV-1 virion infectivity factor (Vif), which mediates A3G polyubiquitination and subsequent cellular depletion. Previous studies have implied that A3G polyubiquitination is essential for Vif-induced degradation. However, the contribution of polyubiquitination to the rate of A3G degradation remains unclear. Here we show that A3G po...

  8. Inhibition of PI3K by ZSTK474 suppressed tumor growth not via apoptosis but G0/G1 arrest

    International Nuclear Information System (INIS)

    Dan, Shingo; Yoshimi, Hisashi; Okamura, Mutsumi; Mukai, Yumiko; Yamori, Takao

    2009-01-01

    Phosphoinositide 3-kinase (PI3K) is a potential target in cancer therapy. Inhibition of PI3K is believed to induce apoptosis. We recently developed a novel PI3K inhibitor ZSTK474 with antitumor efficacy. In this study, we have examined the underlying mode of action by which ZSTK474 exerts its antitumor efficacy. In vivo, ZSTK474 effectively inhibited the growth of human cancer xenografts. In parallel, ZSTK474 treatment suppressed the expression of phospho-Akt, suggesting effective PI3K inhibition, and also suppressed the expression of nuclear cyclin D1 and Ki67, both of which are hallmarks of proliferation. However, ZSTK474 treatment did not increase TUNEL-positive apoptotic cells. In vitro, ZSTK474 induced marked G 0 /G 1 arrest, but did not increase the subdiploid cells or activate caspase, both of which are hallmarks of apoptosis. These results clearly indicated that inhibition of PI3K by ZSTK474 did not induce apoptosis but rather induced strong G 0 /G 1 arrest, which might cause its efficacy in tumor cells.

  9. High level of APOBEC3F/3G editing in HIV-2 DNA vif and pol sequences from antiretroviral-naive patients.

    Science.gov (United States)

    Bertine, Mélanie; Charpentier, Charlotte; Visseaux, Benoit; Storto, Alexandre; Collin, Gilles; Larrouy, Lucile; Damond, Florence; Matheron, Sophie; Brun-Vézinet, Françoise; Descamps, Diane

    2015-04-24

    In HIV-1, hypermutation introduced by APOBEC3F/3G cytidine deaminase activity leads to defective viruses. In-vivo impact of APOBEC3F/3G editing on HIV-2 sequences remains unknown. The objective of this study was to assess the level of APOBEC3F/3G editing in HIV-2-infected antiretroviral-naive patients. Direct sequencing of vif and pol regions was performed on HIV-2 proviral DNA from antiretroviral-naive patients included in the French Agence Nationale de Recherches sur le SIDA et les hépatites virales CO5 HIV-2 cohort. Hypermutated sequences were identified using Hypermut2.0 program. HIV-1 proviral sequences from Genbank were also assessed. Among 82 antiretroviral-naive HIV-2-infected patients assessed, 15 (28.8%) and five (16.7%) displayed Vif proviral defective sequences in HIV-2 groups A and B, respectively. A lower proportion of defective sequences was observed in protease-reverse transcriptase region. A higher median number of G-to-A mutations was observed in HIV-2 group B than in group A, both in Vif and protease-reverse transcriptase regions (P = 0.02 and P = 0.006, respectively). Compared with HIV-1 Vif sequences, a higher number of Vif defective sequences was observed in HIV-2 group A (P = 0.00001) and group B sequences (P = 0.013). We showed for the first time a high level of APOBEC3F/3G editing in HIV-2 sequences from antiretroviral-naive patients. Our study reported a group effect with a significantly higher level of APOBEC3F/3G editing in HIV-2 group B than in group A sequences.

  10. Switchable Synthesis of 4,5-Functionalized 1,2,3-Thiadiazoles and 1,2,3-Triazoles from 2-Cyanothioacetamides under Diazo Group Transfer Conditions.

    Science.gov (United States)

    Filimonov, Valeriy O; Dianova, Lidia N; Galata, Kristina A; Beryozkina, Tetyana V; Novikov, Mikhail S; Berseneva, Vera S; Eltsov, Oleg S; Lebedev, Albert T; Slepukhin, Pavel A; Bakulev, Vasiliy A

    2017-04-21

    High yield solvent-base-controlled, transition metal-free synthesis of 4,5-functionalized 1,2,3-thiadiazoles and 1,2,3-triazoles from 2-cyanothioacetamides and sulfonyl azides is described. Under diazo transfer conditions in the presence of a base in an aprotic solvent 2-cyanothioacetamides operating as C-C-S building blocks produce 5-amino-4-cyano-1,2,3-thiadiazoles exclusively. The use of alkoxide/alcohol system completely switches the reaction course due to the change of one of the reaction centers in the 2-cyanothioacetamide (C-C-N building block) resulting in the formation of 5-sulfonamido-1,2,3-triazole-4-carbothioamide sodium salts as the only products. The latter serve as good precursors for 5-amino-1,2,3-thiadiazole-4-carboximidamides, the products of Cornforth-type rearrangement occurring in neutral protic medium or under acid conditions. According to DFT calculations (B3LYP/6-311+G(d,p)) the rearrangement proceeds via intermediate formation of a diazo compound, and can be catalyzed by acids via the protonation of oxygen atom of the sulfonamide group.

  11. Poly(2,5-dimercapto-1,3,4-thiadiazole) as a Cathode for Rechargeable Lithium Batteries with Dramatically Improved Performance

    KAUST Repository

    Gao, Jie

    2012-05-29

    Organosulfur compounds with multiple thiol groups are promising for high gravimetric energy density electrochemical energy storage. We have synthesized a poly(2,5-dimercapto-1,3,4-thiadiazole) (PDMcT)/poly(3,4-ethylenedioxythiophene) (PEDOT) composite cathode for lithium-ion batteries with a new method and investigated its electrochemical behavior by charge/discharge cycles and cyclic voltammetry (CV) in an ether-based electrolyte. Based on a comparison of the electrochemical performance with a carbonate-based electrolyte, we found a much higher discharge capacity, but also a very attractive cycling performance of PDMcT by using a tetra(ethylene glycol) dimethyl ether (TEGDME)-based electrolyte. The first discharge capacity of the as-synthesized PDMcT/PEDOT composite approached 210 mAh g -1 in the TEGDME-based electrolyte. CV results clearly show that the redox reactions of PDMcT are highly reversible in this TEGDME-based electrolyte. The reversible capacity remained around 120 mAh g -1 after 20 charge/discharge cycles. With improved cycling performance and very low cost, PDMcT could become a very promising cathode material when combined with a TEGDME-based electrolyte. The poor capacity in the carbonate-based electrolyte is a consequence of the irreversible reaction of the DMcT monomer and dimer with the solvent, emphasizing the importance of electrolyte chemistry when studying molecular-based battery materials. The nature of the electrolyte has a dramatic effect on the performance of poly(2,5-dimercapto-1,3,4-thiadiazole) (PDMcT) as a cathode material in lithium-ion batteries. Whereas the use of an ethylene/diethyl carbonate (EC/DEC)-based electrolyte resulted in very poor performance, the use of a tetra(ethylene glycol) dimethyl ether (TEGDME)-based electrolyte dramatically improved the performance in terms of both the discharge capacity and capacity retention (see scheme). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Broad Absorption Line Quasar catalogues with Supervised Neural Networks

    International Nuclear Information System (INIS)

    Scaringi, Simone; Knigge, Christian; Cottis, Christopher E.; Goad, Michael R.

    2008-01-01

    We have applied a Learning Vector Quantization (LVQ) algorithm to SDSS DR5 quasar spectra in order to create a large catalogue of broad absorption line quasars (BALQSOs). We first discuss the problems with BALQSO catalogues constructed using the conventional balnicity and/or absorption indices (BI and AI), and then describe the supervised LVQ network we have trained to recognise BALQSOs. The resulting BALQSO catalogue should be substantially more robust and complete than BI-or AI-based ones.

  13. Antiradiation Antitoxin IgG : Immunological neutralization of Radiation Toxins at Acute Radiation Syndromes.

    Science.gov (United States)

    Popov, Dmitri; Maliev, Slava

    Introduction: High doses of radiation induce apoptotic necrosis of radio-sensitive cells. Mild doses of radiation induce apoptosis or controlled programmed death of radio-sensitive cells with-out development of inflammation and formation of Radiation Toxins. Cell apoptotic necrosis initiates Radiation Toxins (RT)formation. Radiation Toxins play an important role as a trig-ger mechanism for inflammation development and cell lysis. If an immunotherapy approach to treatment of the acute radiation syndromes (ARS) were to be developed, a consideration could be given to neutralization of radiation toxins (Specific Radiation Determinants-SRD) by specific antiradiation antibodies. Therapeutic neutralization effects of the blocking anti-radiation antibodies on the circulated RT had been studied. Radiation Toxins were isolated from the central lymph of irradiated animals with Cerebrovascular(Cv ARS),Cardiovascular (Cr ARS),Gastrointestinal(Gi ARS) and Haemopoietic (Hp ARS) forms of ARS. To accomplish this objective, irradiated animals were injected with a preparation of anti-radiation immunoglobulin G (IgG) obtained from hyperimmune donors. Radiation-induced toxins that we call Specific Radiation Determinants (SRD) possess toxic (neurotoxic, haemotoxic) characteristics as well as specific antigenic properties. Depending on direct physiochemical radiation damage, they can induce development of many of the pathological processes associated with ARS. We have tested several specific hyperimmune IgG preparations against these radiation toxins and ob-served that their toxic properties were neutralized by the specific antiradiation IgGs. Material and Methods: A scheme of experiments was following: 1.Isolation of radiation toxins (RT) from the central lymph of irradiated animals with different form of ARS. 2.Transformation of a toxic form of the RT to a toxoid form of the RT. 3.Immunization of radiation naive animals. Four groups of rabbits were inoculated with a toxoid form of SRD

  14. Serum-induced G0/G1 transition in chemically transformed 3T3 cells

    International Nuclear Information System (INIS)

    Gray, H.E.; Buchou, T.; Mester, J.

    1987-01-01

    Quiescent, chemically transformed (benzo-a-pyrene) BALB/c 3T3 cells (BP A31) enter the cell division cycle when exposed to complete medium containing 10% fetal calf serum (FCS); the number of cells recruited is a function of the duration of serum exposure. The recruitment of cells by short (<4 h) serum pulses is not inhibited by simultaneous exposure to cycloheximide (CH), and therefore the initial commitment does not require protein synthesis. The cells enter S phase with a constant delay following the removal of CH, even if CH exposure has been continued for as long as 20 h after the end of the serum pulse. The cell recruitment by serum pulses was inhibited by 5,6-dichloro-1-β-D-ribofuranosyl-benzimidazole (DRB), an inhibitor of cytoplasmic mRNA accumulation. These data suggest that serum exposure produces a stable memory that is necessary and sufficient for the eventual progression through G1 to S phase that occurs when protein synthesis is resumed after the removal of CH; this memory probably consists of mRNA species that are induced by serum and that are stable in the absence of protein synthesis. Unexpectedly, pretreatment of quiescent BP A31 cells with CH (8-24 h) dramatically increased the fraction of the total cell population that is recruited by a serum pulse of fixed duration

  15. FORMULASI STRATEGI PENINGKATAN PRODUKSI DOMBA CV MITRA TANI FARM, CIAMPEA, BOGOR

    Directory of Open Access Journals (Sweden)

    Amalia Sholehana

    2014-04-01

    Full Text Available ABSTRACTThis research was conducted to formulate to increase the sheep production at CV Mitra Tani Farm (CV MT Farm, Ciampea, Bogor. The research was conducted using descriptive analysis by analyzing the problem experienced by CV. MitraTani Farm. Primary data and secondary data were gathered at this research. The research was also conducted using several analytical methods such as value chain mapping, internal factor evaluation (IFE and external factor evaluation (EFE matrix, SWOT and quantitative strategic planning matrix (QSPM. Based on the value chain analysis, the current production of sheep at CV MT farm is highly depending on the supply from its partners and internal farmers. According to the IFE and EFE results, the differences of each weighted values were respectively 2,120 and 0,686 so the position of the company in the SWOT matrix was situated at Quadrant I. Therefore the company needs to use a growth strategy. The QSPM sequenced the strategy priority as follow (1 increasing the number of lambs, (2 developing the management, (3 strengthening the capital and ownership, (4 improving the quality through technology. The result of the gross profit margin calculation, if the sheep‘s selling is increased up to 1000 sheep per month then the possible annual profit that can be earned by CV MT farm is 40,34% of the total production.Keywords: MT Farm, sheep production, strategies, SWOT, QSPM, gross profit marginABSTRAKPenelitian ini dilakukan untuk memformulasikan strategi peningkatan produksi domba di CV Mitra Tani Farm (CV MT Farm, Ciampea, Bogor. Pendekatan penelitian yang diterapkan adalah analisis deskriptif yang dilakukan dengan mempelajari permasalahan dari objek yang diteliti. Data yang dikumpulkan dalam penelitian ini adalah data primer dan data sekunder. Penelitian dilakukan menggunakan alat analisis berupa pemetaan rantai nilai,  matriks IFE (Internal Factor Evaluation dan EFE (External Factor Evaluation, SWOT, dan QSPM (Quantitative

  16. The ASAS-SN bright supernova catalogue - III. 2016

    Science.gov (United States)

    Holoien, T. W.-S.; Brown, J. S.; Stanek, K. Z.; Kochanek, C. S.; Shappee, B. J.; Prieto, J. L.; Dong, Subo; Brimacombe, J.; Bishop, D. W.; Bose, S.; Beacom, J. F.; Bersier, D.; Chen, Ping; Chomiuk, L.; Falco, E.; Godoy-Rivera, D.; Morrell, N.; Pojmanski, G.; Shields, J. V.; Strader, J.; Stritzinger, M. D.; Thompson, Todd A.; Woźniak, P. R.; Bock, G.; Cacella, P.; Conseil, E.; Cruz, I.; Fernandez, J. M.; Kiyota, S.; Koff, R. A.; Krannich, G.; Marples, P.; Masi, G.; Monard, L. A. G.; Nicholls, B.; Nicolas, J.; Post, R. S.; Stone, G.; Wiethoff, W. S.

    2017-11-01

    This catalogue summarizes information for all supernovae discovered by the All-Sky Automated Survey for SuperNovae (ASAS-SN) and all other bright (mpeak ≤ 17), spectroscopically confirmed supernovae discovered in 2016. We then gather the near-infrared through ultraviolet magnitudes of all host galaxies and the offsets of the supernovae from the centres of their hosts from public data bases. We illustrate the results using a sample that now totals 668 supernovae discovered since 2014 May 1, including the supernovae from our previous catalogues, with type distributions closely matching those of the ideal magnitude limited sample from Li et al. This is the third of a series of yearly papers on bright supernovae and their hosts from the ASAS-SN team.

  17. Moments of the Spin Structure Functions g1p and g1d for 0.05 < Q2 < 3.0 GeV2

    Energy Technology Data Exchange (ETDEWEB)

    Prok, Yelena; Bosted, Peter; Burkert, Volker; Deur, Alexandre; Dharmawardane, Kahanawita; Dodge, Gail; Griffioen, Keith; Kuhn, Sebastian; Minehart, Ralph; Adams, Gary; Amaryan, Moscov; Amaryan, Moskov; Anghinolfi, Marco; Asryan, G.; Audit, Gerard; Avagyan, Harutyun; Baghdasaryan, Hovhannes; Baillie, Nathan; Ball, J.P.; Ball, Jacques; Baltzell, Nathan; Barrow, Steve; Battaglieri, Marco; Beard, Kevin; Bedlinskiy, Ivan; Bektasoglu, Mehmet; Bellis, Matthew; Benmouna, Nawal; Berman, Barry; Biselli, Angela; Blaszczyk, Lukasz; Boyarinov, Sergey; Bonner, Billy; Bouchigny, Sylvain; Bradford, Robert; Branford, Derek; Briscoe, William; Brooks, William; Bultmann, S.; Bueltmann, Stephen; Butuceanu, Cornel; Calarco, John; Careccia, Sharon; Carman, Daniel; Casey, Liam; Cazes, Antoine; Chen, Shifeng; Cheng, Lu; Cole, Philip; Collins, Patrick; Coltharp, Philip; Cords, Dieter; Corvisiero, Pietro; Crabb, Donald; Crede, Volker; Cummings, John; Dale, Daniel; Dashyan, Natalya; De Masi, Rita; De Vita, Raffaella; De Sanctis, Enzo; Degtiarenko, Pavel; Denizli, Haluk; Dennis, Lawrence; Dhuga, Kalvir; Dickson, Richard; Djalali, Chaden; Doughty, David; Dugger, Michael; Dytman, Steven; Dzyubak, Oleksandr; Egiyan, Hovanes; Egiyan, Kim; Elfassi, Lamiaa; Elouadrhiri, Latifa; Eugenio, Paul; Fatemi, Renee; Fedotov, Gleb; Feldman, Gerald; Fersch, Robert; Feuerbach, Robert; Forest, Tony; Fradi, Ahmed; Funsten, Herbert; Garcon, Michel; Gavalian, Gagik; Gevorgyan, Nerses; Gilfoyle, Gerard; Giovanetti, Kevin; Girod, Francois-Xavier; Goetz, John; Golovach, Evgeny; Gothe, Ralf; Guidal, Michel; Guillo, Matthieu; Guler, Nevzat; Guo, Lei; Gyurjyan, Vardan; Hadjidakis, Cynthia; Hafidi, Kawtar; Hakobyan, Hayk; Hanretty, Charles; Hardie, John; Hassall, Neil; Heddle, David; Hersman, F.; Hicks, Kenneth; Hleiqawi, Ishaq; Holtrop, Maurik; Huertas, Marco; Hyde, Charles; Ilieva, Yordanka; Ireland, David; Ishkhanov, Boris; Isupov, Evgeny; Ito, Mark; Jenkins, David; Jo, Hyon-Suk; Johnstone, John; Joo, Kyungseon; Juengst, Henry; Kalantarians, Narbe; Keith, Christopher; Kellie, James; Khandaker, Mahbubul; Kim, Kui; Kim, Kyungmo; Kim, Wooyoung; Klein, Andreas; Klein, Franz; Klusman, Mike; Kossov, Mikhail; Krahn, Zebulun; Kramer, Laird; Kubarovsky, Valery; Kuhn, Joachim; Kuleshov, Sergey; Kuznetsov, Viacheslav; Lachniet, Jeff; Laget, Jean; Langheinrich, Jorn; Lawrence, Dave; Lima, Ana; Livingston, Kenneth; Lu, Haiyun; Lukashin, K.; MacCormick, Marion; Marchand, Claude; Markov, Nikolai; Mattione, Paul; McAleer, Simeon; McKinnon, Bryan; McNabb, John; Mecking, Bernhard; Mestayer, Mac; Meyer, Curtis; Mibe, Tsutomu; Mikhaylov, Konstantin; Mirazita, Marco; Miskimen, Rory; Mokeev, Viktor; Morand, Ludyvine; Moreno, Brahim; Moriya, Kei; Morrow, Steven; Moteabbed, Maryam; Mueller, James; Munevar Espitia, Edwin; Mutchler, Gordon; Nadel-Turonski, Pawel; Nasseripour, Rakhsha; Niccolai, Silvia; Niculescu, Gabriel; Niculescu, Maria-Ioana; Niczyporuk, Bogdan; Niroula, Megh; Niyazov, Rustam; Nozar, Mina; O' Rielly, Grant; Osipenko, Mikhail; Ostrovidov, Alexander; Park, Kijun; Pasyuk, Evgueni; Paterson, Craig; Anefalos Pereira, S.; Philips, Sasha; Pierce, J.; Pivnyuk, Nikolay; Pocanic, Dinko; Pogorelko, Oleg; Popa, Iulian; Pozdnyakov, Sergey; Preedom, Barry; Price, John; Procureur, Sebastien; Protopopescu, Dan; Qin, Liming; Raue, Brian; Riccardi, Gregory; Ricco, Giovanni; Ripani, Marco; Ritchie, Barry; Rosner, Guenther; Rossi, Patrizia; Rowntree, David; Rubin, Philip; Sabatie, Franck; Salamanca, Julian; Salgado, Carlos; Santoro, Joseph; Sapunenko, Vladimir; Schumacher, Reinhard; Seely, Mikell; Serov, Vladimir; Sharabian, Youri; Sharov, Dmitri; Shaw, Jeffrey; Shvedunov, Nikolay; Skabelin, Alexander; Smith, Elton; Smith, Lee; Sober, Daniel; Sokhan, Daria; Stavinskiy, Aleksey; Stepanyan, Samuel; Stepanyan, Stepan; Stokes, Burnham; Stoler, Paul; Strakovski, Igor; Strauch, Steffen; Suleiman, Riad; Taiuti, Mauro; Tedeschi, David; Tkabladze, Avtandil; Tkachenko, Svyatoslav; Todor, Luminita; Ungaro, Maurizio; V

    2009-02-01

    The spin structure functions $g_1$ for the proton and the deuteron have been measured over a wide kinematic range in $x$ and \\Q2 using 1.6 and 5.7 GeV longitudinally polarized electrons incident upon polarized NH$_3$ and ND$_3$ targets at Jefferson Lab. Scattered electrons were detected in the CEBAF Large Acceptance Spectrometer, for $0.05 < Q^2 < 5 $\\ GeV$^2$ and $W < 3$ GeV. The first moments of $g_1$ for the proton and deuteron are presented -- both have a negative slope at low \\Q2, as predicted by the extended Gerasimov-Drell-Hearn sum rule. The first result for the generalized forward spin polarizability of the proton $\\gamma_0^p$ is also reported, and shows evidence of scaling above $Q^2$ = 1.5 GeV$^2$. Although the first moments of $g_1$ are consistent with Chiral Perturbation Theory (\\ChPT) calculations up to approximately $Q^2 = 0.06$ GeV$^2$, a significant discrepancy is observed between the $\\gamma_0^p$ data and \\ChPT\\ for $\\gamma_0^p$,even at the lowest \\Q2.

  18. The presence of PAI-1 4G/5G and ACE DD genotypes increases the risk of early-stage AVF thrombosis in hemodialysis patients.

    Science.gov (United States)

    Güngör, Yahya; Kayataş, Mansur; Yıldız, Gürsel; Özdemir, Öztürk; Candan, Ferhan

    2011-01-01

    In this study, we investigated the relationship between early arteriovenous fistula (AVF) thrombosis with angiotensin-converting enzyme (ACE) gene and thrombophilic factor gene polymorphisms. Thirty-five patients who suffered from three or more fistula thrombosis episodes in the early period after AVF operation and 33 control patients with no history of thrombosis for at least 3 years were enrolled in this study. Factor V G1691A Leiden, factor V H1299R (R2), prothrombin G20210A, factor XIIIV34L, β-fibrinogen-455 G-A, glycoprotein IIIa L33P human platelet antigens (HPA-1), methylenetetrahydrofolate reductase C677T, and methylenetetrahydrofolate reductase A1298C gene polymorphisms were similar in both groups (p > 0.05). Plasminogen activator inhibitor 1 (PAI-1) 4G/5G genotype in the study group and 4G/4G genotype in the control group were significantly higher (p = 0.014). No significant difference was detected in terms of the 5G/5G genotype. With regard to the ACE gene polymorphism, the control group showed more ID genotype (19/33, 57.6%), whereas the study group showed more DD genotype (17/35, 48.6%). II genotype was similar in both groups (x(2) = 7.40, p = 0.025). The rate of ACE inhibitor-angiotensin II receptor blockers use was 5/35 in the study group (14.3%) and 5/33 in the control group (15.2%). Individuals with PAI-1 4G/5G genotype showed 5.03 times more risk of thrombosis when compared with 4G/4G and 5G/5G genotypes [p = 0.008, OR = 5.03, 95% confidence interval (1.44:17.64)]. Individuals with ACE DD genotype showed 4.25 times more risk of thrombosis when compared with II and ID [p = 0.008, OR = 4.25, 95% confidence interval (1.404:12.83)]. PAI-1 4G/5G and ACE DD genotypes are associated with increased risk for early AVF thrombosis.

  19. Optimization of ultrasound and microwave assisted extractions of polyphenols from black rice (Oryza sativa cv. Poireton) husk.

    Science.gov (United States)

    Jha, Pankaj; Das, Arup Jyoti; Deka, Sankar Chandra

    2017-11-01

    Phenolic compounds were extracted from the husk of milled black rice (cv. Poireton) by using a combination of ultrasound assisted extraction and microwave assisted extraction. Extraction parameters were optimized by response surface methodology according to a three levels, five variables Box-Behnken design. The appropriate process variables (extraction temperature and extraction time) to maximize the ethanolic extraction of total phenolic compounds, flavonoids, anthocyanins and antioxidant activity of the extracts were obtained. Extraction of functional components with varying ethanol concentration and microwave time were significantly affected by the process variables. The best possible conditions obtained by RSM for all the factors included 10.02 min sonication time, 49.46 °C sonication temperature, 1:40.79 (w/v) solute solvent ratio, 67.34% ethanol concentration, and 31.11 s microwave time. Under the given solutions, the maximum extraction of phenolics (1.65 mg/g GAE), flavonoids (3.04 mg/100 g), anthocyanins (3.39 mg/100 g) and antioxidants (100%) were predicted, while the experimental values included 1.72 mg/g GAE of total phenolics, 3.01 mg/100 g of flavonoids, 3.36 mg/100 g of anthocyanins and 100% antioxidant activity. The overall results indicated positive impact of co-application of microwave and ultrasound assisted extractions of phenolic compounds from black rice husk.

  20. Efectividad de cepas rizobianas nativas de sabana en Vigna unguiculata (L. Walp. cv. C4A-3

    Directory of Open Access Journals (Sweden)

    Juliana Mayz

    2010-07-01

    fertilizer. In Venezuela, cowpea is highly consumed and is cultivated in eastern savannahs, whose soil characteristics may negatively affect rhizobial population. These expositions reinforce the importance of the evaluation of the native rhizobial flora and emphasize the necessity to increase the exploitation of the Biological Nitrogen Fixation. In this context, 6 rhizobial strains isolated from cowpea cv. Tejero Criollo non-inoculated and previously catalogued as effectives (JV91, JV94 y JV101 and ineffectives (JV99, JV103, y JV104 in cultivar TC9-6 were evaluated in the cultivar C4A-3. The experiment was carried out in greenhouse by 45 days, where in addition, two non-inoculated control treatments were included. Suspension of individually cultivated strains was used for inoculation. Accordingly with nodulation typology (nodule number, total dry weight and per nodule and colour, growth parameter values (shoot dry weight, height and leaves number and nitrogen concentration and total nitrogen estimates, the strains JV91, JV99 and JV101 were the most effective in nitrogen fixation. Total nitrogen and concentration correlated significantly with dry weight and height of shoots and leaves number. The results show the existence of effective strains in savannah soils for this cultivar, and emphasize the importance of evaluating the indigenous strains, before proceeding to inoculate with foreign strains. Key words: Rhizobium; cowpea; nitrogen fixation; Venezuela.

  1. A new version of the European tsunami catalogue: updating and revision

    Directory of Open Access Journals (Sweden)

    S. Tinti

    2001-01-01

    Full Text Available A new version of the European catalogue of tsunamis is presented here. It differs from the latest release of the catalogue that was produced in 1998 and is known as GITEC tsunami catalogue in some important aspects. In the first place, it is a database built on the Visual FoxPro 6.0 DBMS that can be used and maintained under the PC operating systems currently available. Conversely, the GITEC catalogue was compatible only with Windows 95 and older PC platforms. In the second place, it is enriched by new facilities and a new type of data, such as a database of pictures that can be accessed easily from the main screen of the catalogue. Thirdly, it has been updated by including the newly published references. Minute and painstaking search for new data has been undertaken to re-evaluate cases that were not included in the GITEC catalogue, though they were mentioned in previous catalogues; the exclusion was motivated by a lack of data. This last work has focused so far on Italian cases of the last two centuries. The result is that at least two events have been found which deserve inclusion in the new catalogue: one occurred in 1809 in the Gulf of La Spezia, and the other occurred in 1940 in the Gulf of Palermo. Two further events are presently under investigation.

  2. International Atomic Energy Agency Publications. Catalogue 1986-1999

    International Nuclear Information System (INIS)

    2000-11-01

    This catalogue lists all sales publications of the International Atomic Energy Agency issued from 1986 up to the end of 1999 and still available. Some earlier titles which form part of an established series or are still considered important have also been included. The catalogue is in CD-ROM format

  3. Activation of salicylic acid metabolism and signal transduction can enhance resistance to Fusarium wilt in banana (Musa acuminata L. AAA group, cv. Cavendish).

    Science.gov (United States)

    Wang, Zhuo; Jia, Caihong; Li, Jingyang; Huang, Suzhen; Xu, Biyu; Jin, Zhiqiang

    2015-01-01

    Fusarium wilt caused by the fungus Fusarium oxysporum f. sp. cubens (Foc) is the most serious disease that attacks banana plants. Salicylic acid (SA) can play a key role in plant-microbe interactions. Our study is the first to examine the role of SA in conferring resistance to Foc TR4 in banana (Musa acuminata L. AAA group, cv. Cavendish), which is the greatest commercial importance cultivar in Musa. We used quantitative real-time reverse polymerase chain reaction (qRT-PCR) to analyze the expression profiles of 45 genes related to SA biosynthesis and downstream signaling pathways in a susceptible banana cultivar (cv. Cavendish) and a resistant banana cultivar (cv. Nongke No. 1) inoculated with Foc TR4. The expression of genes involved in SA biosynthesis and downstream signaling pathways was suppressed in a susceptible cultivar and activated in a resistant cultivar. The SA levels in each treatment arm were measured using high-performance liquid chromatography. SA levels were decreased in the susceptible cultivar and increased in the resistant cultivar. Finally, we examined the contribution of exogenous SA to Foc TR4 resistance in susceptible banana plants. The expression of genes involved in SA biosynthesis and signal transduction pathways as well as SA levels were significantly increased. The results suggest that one reason for banana susceptibility to Foc TR4 is that expression of genes involved in SA biosynthesis and SA levels are suppressed and that the induced resistance observed in banana against Foc TR4 might be a case of salicylic acid-dependent systemic acquired resistance.

  4. OpenCV 3.0 computer vision with Java

    CERN Document Server

    Baggio, Daniel Lélis

    2015-01-01

    If you are a Java developer, student, researcher, or hobbyist wanting to create computer vision applications in Java then this book is for you. If you are an experienced C/C++ developer who is used to working with OpenCV, you will also find this book very useful for migrating your applications to Java. All you need is basic knowledge of Java, with no prior understanding of computer vision required, as this book will give you clear explanations and examples of the basics.

  5. APOBEC3G inhibits HIV-1 RNA elongation by inactivating the viral trans-activation response element.

    Science.gov (United States)

    Nowarski, Roni; Prabhu, Ponnandy; Kenig, Edan; Smith, Yoav; Britan-Rosich, Elena; Kotler, Moshe

    2014-07-29

    Deamination of cytidine residues in viral DNA is a major mechanism by which APOBEC3G (A3G) inhibits vif-deficient human immunodeficiency virus type 1 (HIV-1) replication. dC-to-dU transition following RNase-H activity leads to viral cDNA degradation, production of non-functional proteins, formation of undesired stop codons and decreased viral protein synthesis. Here, we demonstrate that A3G provides an additional layer of defense against HIV-1 infection dependent on inhibition of proviral transcription. HIV-1 transcription elongation is regulated by the trans-activation response (TAR) element, a short stem-loop RNA structure required for elongation factors binding. Vif-deficient HIV-1-infected cells accumulate short viral transcripts and produce lower amounts of full-length HIV-1 transcripts due to A3G deamination of the TAR apical loop cytidine, highlighting the requirement for TAR loop integrity in HIV-1 transcription. We further show that free single-stranded DNA (ssDNA) termini are not essential for A3G activity and a gap of CCC motif blocked with juxtaposed DNA or RNA on either or 3'+5' ends is sufficient for A3G deamination. These results identify A3G as an efficient mutator and that deamination of (-)SSDNA results in an early block of HIV-1 transcription. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. An Assessment of Online Public Access Catalogue (OPAC ...

    African Journals Online (AJOL)

    The main purpose of this study was to assess the computerized catalogue and its utilization in university libraries in Lagos state. Survey research method was employed for the study. The population for the study was drawn from two university libraries in Lagos state that have automated their catalogues. These libraries are ...

  7. The ASAS-SN bright supernova catalogue - III. 2016

    DEFF Research Database (Denmark)

    Holoien, T. W. -S.; Brown, J. S.; Stanek, K. Z.

    2017-01-01

    This catalogue summarizes information for all supernovae discovered by the All-Sky Automated Survey for SuperNovae (ASAS-SN) and all other bright (m(peak)d......This catalogue summarizes information for all supernovae discovered by the All-Sky Automated Survey for SuperNovae (ASAS-SN) and all other bright (m(peak)d...

  8. Emgu CV essentials

    CERN Document Server

    Shi, Shin

    2013-01-01

    This book provides a practical guide to Emgu CV libraries, with sample code and examples used throughout to explain the concepts clearly. Each chapter deals with a different aspect of the Computer Vision field and the implementation of that topic in Emgu CV.If you are a C# programmer working on computer vision projects, this book is for you. You should have prior experience with C#.

  9. VizieR Online Data Catalog: WATCH Solar X-Ray Burst Catalogue (Crosby+ 1998)

    Science.gov (United States)

    Crosby, N.; Lund, N.; Vilmer, N.; Sunyaev, R.

    1998-01-01

    Catalogue containing solar X-ray bursts measured by the Danish Wide Angle Telescope for Cosmic Hard X-Rays (WATCH) experiment aboard the Russian satellite GRANAT in the deca-keV energy range. Table 1 lists the periods during which solar observations with WATCH are available (WATCH ON-TIME) and where the bursts listed in the catalogue have been observed. (2 data files).

  10. Serum IgG2 and tissue IgG2 plasma cell elevation in orbital IgG4-related disease (IgG4-RD): Potential use in IgG4-RD assessment.

    Science.gov (United States)

    Chan, Anita S Y; Mudhar, Hardeep; Shen, Sunny Yu; Lang, Stephanie S; Fernando, Malee; Hilmy, Maryam Hazly; Guppy, Naomi Jayne; Rennie, Ian; Dunkley, Lisa; Al Jajeh, Issam

    2017-11-01

    To determine the role of serum and tissue IgG2 in orbital biopsies with the histological features of IgG4-related disease (IgG4-RD) in comparison with non-IgG4-related orbital inflammatory disorders (OID), including autoimmune disorders. This is an international (Sheffield, UK, and Singapore) collaborative, retrospective case review of 69 patients (38 from Singapore National Eye Centre and 31 from Royal Hallamshire Hospital, Sheffield) with orbital inflammatory biopsies between 2002 and 2016. Clinical information and histology were reviewed and cases were classified into three groups: Group 1: IgG4-RD orbital inflammation (n=43); Group 2: idiopathic OID (n=12) and Group 3: autoimmune OID (n=14). Serum IgG1, IgG2, IgG3 and IgG4 levels were collated where available and immunohistochemistry (IHC) for tissue IgG2 plasma cells was performed. Dual IHC showed IgG2 plasma cells as a distinct population from IgG4 plasma cells. Significant (twofold) serum IgG2 elevation was noted among IgG4-RD (group 1), idiopathic (group 2) and autoimmune OID (group 3). Similarly, significant elevation of tissue IgG2 plasma cells was also seen among IgG4-RD (group 1), idiopathic and autoimmune OID (groups 2 and 3). Significant elevations of serum IgG2 and tissue IgG2 plasma cells are present in orbital IgG4-RD in comparison with non-IgG4 orbital inflammation (idiopathic and autoimmune OID), suggesting that IgG2 may play a role in IgG4-RD. A serum IgG2 cut-off >5.3g/L was found to be 80% sensitive and 91.7% specific for orbital IgG4-RD, with an accuracy of 0.90. Tissue IgG2 and IgG4 subclass reporting may provide additional insight regarding the 'IgG4-RD' pathogenesis. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  11. Application of 1-methylcyclopropene on mango fruit (Cv. Kesar): potential for shelf life enhancement and retention of quality.

    Science.gov (United States)

    Sakhale, B K; Gaikwad, S S; Chavan, R F

    2018-02-01

    The present investigation was carried out to study the effect of gaseous application of 1-methylcyclopropene (1-MCP) on quality and shelf life of mango fruits of Cv. Kesar. The freshly harvested matured mango fruits were washed, cleaned and treated with fungicide at 500 ppm concentration for 10 min. The fruits were then subjected to 1-MCP treatment at different concentrations (500, 1000, 1500, 2000 ppb) and exposed for 18 and 24 h at 20 °C temperature in an air tight chamber along with control sample. The results indicated that the ripening in the early stages of mango was delayed by 1-MCP and shelf life of the fruits was increased with increase in the concentration of 1-MCP, also the physico-chemical changes such as percent physiological loss in weight of fruit, total soluble solids and colour was slowly increased and ascorbic acid content was effectively reduced. 1-MCP treatment of 2000 ppb for 24 h exposure time gave the best results for percent physiological loss in weight of fruit from 6.1 to 13% and ascorbic acid content from 80.28 to 22.34 mg/100 g, total soluble solids increased from 7.3 to 16.23 °Brix and the colour was improved from 50.9 to 68.6 h with shelf life of 20 days.

  12. Evaluation of the hemoglobin A1c-analyzer TOSOH HLC-723 G7.

    Science.gov (United States)

    Gremmels, Heinz-Detlef; Richter, Anja; Watzke, Ivonne

    2003-01-01

    The TOSOH HLC-723 G7 is a compact analyzer designed for the measurement of HbA1c under routine laboratory conditions. The analyzer has an automatic blood tube supply and positive sample identification. Samples are transported automatically via racks in a continuous-load mode, cap piercing is optional. Tests devoted to the assessment of reproducibility and accuracy of analytical results indicated that over a test period of 17 days, the intra-assay variation (CV) was 1.79%, and the inter-assay variation 2.60%, respectively. A comparison with the predecessor model G5 showed a very good correlation (r = 0.997, y = 1.0041x - 0.00172; n = 149). The presence of high triglyceride, bilirubin or urea concentrations in patient samples did not influence the analytical precision. The labile HbA1c fraction (L-A1c) is clearly separated during chromatography and thus does not compromise HbA1c analysis. With a protocol of 1.2 minutes, the TOSOH G7 is a very fast analyzer, designed for laboratories with a high throughput of samples.

  13. G 126.1-0.8-14: A molecular shell related to Sh2-187

    Science.gov (United States)

    Cichowolski, S.; Pineault, S.; Gamen, R.; Ortega, M. E.; Arnal, E. M.; Suad, L. A.

    2014-10-01

    We present a multi-wavelength study of a region where a well defined molecular shell, named G 126.1-0.8-14, is observed. The distance of G 126.1-0.8-14 is about 1 kpc. Based on HI and CO data we analyze the atomic and molecular gas related to the structure and estimate its main physical properties. From the radio continuum and infrared data we analyze whether the emission associated with G 126.1-0.8-14 has a thermal origin. To disentangle the possible origin of the shell, and given the lack of catalogued O-type stars in the area, we observed with GEMINI the spectra of four OB stars located in projection inside the shell, to get their accurate spectral types and distances. The young HII region Sh2-187 is located onto the densest part of this molecular shell. A search for young stellar object candidates (cYSOs) was made using infrared point source catalogs. Several cYSOs are found spread out onto the shell. Based on all the available data, we discuss the possible origin of G 126.1-0.8-14 as well as its role in the formation of a new generation of stars.

  14. Innovative maintenance concept 0f Siemens Energy Service. Turbine documentation in an online catalogue; Innovatives Instandhaltungskonzept bei Siemens Energy Service. Turbinendokumentation als Onlinekatalog

    Energy Technology Data Exchange (ETDEWEB)

    Bitzer, Gerd [Wessendorf Software and Consulting, Berlin (Germany); Stass, Georg [Tema Technologie Marketing AG, Berlin (Germany)

    2010-10-04

    For optimization of its maintenance services, Siemens Energy Services has drawn up an online catalogue as a standardized solution for turbine documentation for customers and service technicians. The new catalogue offers power plant operators internet access to the current documentation of service-relevant replacement parts for machinery. The catalogues are based on SAP data using the Linkone software; each of them has up to 3,000 material items and 1,000 illustrations of replacement parts depending on the type of turbine. The project partner was the Berlin consulting service Wessendorf Software + Consulting (WSC) who have vast experience in the implementation of international catalogue and documentation projects with SAP software. After a project period of 15 months, the innovative solution was implemented in April 2010 and then launched in the market. (orig.)

  15. Frequency Of C3435 Mdr1 And A6896g Cyp3a5 Single Nucleotide Polymorphism in an Iranian Population and Comparison with Other Ethnic Groups

    Directory of Open Access Journals (Sweden)

    N. AZARPIRA

    2006-11-01

    Full Text Available Background:It is well recognized that different patients respond in different ways to medications. The inter-individual variations are greater than the intera- individual variations,a finding consistent with the notion that inheritance is a determinant of drug responses. The recent identification of genetic polymorphisms in drug-metabolizing enzymes and drug transporters led to the hypothesis that genetic factors may be implicated in this interindividual variation. Single nucleotide polymorphism in common metabolic pathway,cytochrome P450 and common transporter,multidrug resistance-1 gene are two important sites that might involve clinically significant genetic variations. Ethnicity greatly influences these genetic polymorphism distributions. Methods: We studied the inheritance patterns of polymorphisms for MDR1 and CYP3A5 genes in the Iranian population and compared its genotype and allele frequencies with 3 different ethnic groups: Caucasian (United Kingdom, Chinese and Japanese. Results: We found striking differences in the distribution of MDR allelic variants between Iranian,Japanese and Chinese (p<0.02 and similar between the Iranian and Caucasian population.(p=0.06.Almost 50% of Iranian and Caucasian individuals were homozygous carriers of the variant T allele compared with 32% of the Japanese and 43% of the Chinese (p<0.02.More than half of Iranian subjects have at least one T allele,with lower P-gp level in small intestine.We also noted dramatic differences in the CYP3A5 alleles and genotypes distribution between Iranian subjects with other compared populations.99% of Iranian individuals were homozygous carriers of the variant G allele compared with about 70% of the Chinese and Japanese and 19% of the Caucasian population. The G/G genotype has a very low level of active cytochrome P450 enzyme.Conclusion:Our results emphasize the role of ethnicity in interindividual variability of the pharmacokinetic and pharmacodynamic characteristics

  16. Learning openCV computer vision with the openCV library

    CERN Document Server

    Bradski, Gary

    2008-01-01

    Learning OpenCV puts you right in the middle of the rapidly expanding field of computer vision. Written by the creators of OpenCV, the widely used free open-source library, this book introduces you to computer vision and demonstrates how you can quickly build applications that enable computers to see" and make decisions based on the data. With this book, any developer or hobbyist can get up and running with the framework quickly, whether it's to build simple or sophisticated vision applications

  17. The PMA Catalogue as a realization of the extragalactic reference system in optical and near infrared wavelengths

    Science.gov (United States)

    Akhmetov, Volodymyr S.; Fedorov, Peter N.; Velichko, Anna B.

    2018-04-01

    We combined the data from the Gaia DR1 and Two-Micron All Sky Survey (2MASS) catalogues in order to derive the absolute proper motions more than 420 million stars distributed all over the sky in the stellar magnitude range 8 mag 2MASS catalogue objects, the 2-dimensional median filter was used. The PMA system of proper motion has been obtained by direct link to 1.6 millions extragalactic sources. The short analysis of the absolute proper motion of the PMA stars Catalogue is presented in this work. From a comparison of this data with same stars from the TGAS, UCAC4 and PPMXL catalogues, the equatorial components of the mutual rotation vector of these coordinate systems are determined.

  18. Catalogue of knowledge and skills for sleep medicine.

    Science.gov (United States)

    Penzel, Thomas; Pevernagie, Dirk; Dogas, Zoran; Grote, Ludger; de Lacy, Simone; Rodenbeck, Andrea; Bassetti, Claudio; Berg, Søren; Cirignotta, Fabio; d'Ortho, Marie-Pia; Garcia-Borreguero, Diego; Levy, Patrick; Nobili, Lino; Paiva, Teresa; Peigneux, Philippe; Pollmächer, Thomas; Riemann, Dieter; Skene, Debra J; Zucconi, Marco; Espie, Colin

    2014-04-01

    Sleep medicine is evolving globally into a medical subspeciality in its own right, and in parallel, behavioural sleep medicine and sleep technology are expanding rapidly. Educational programmes are being implemented at different levels in many European countries. However, these programmes would benefit from a common, interdisciplinary curriculum. This 'catalogue of knowledge and skills' for sleep medicine is proposed, therefore, as a template for developing more standardized curricula across Europe. The Board and The Sleep Medicine Committee of the European Sleep Research Society (ESRS) have compiled the catalogue based on textbooks, standard of practice publications, systematic reviews and professional experience, validated subsequently by an online survey completed by 110 delegates specialized in sleep medicine from different European countries. The catalogue comprises 10 chapters covering physiology, pathology, diagnostic and treatment procedures to societal and organizational aspects of sleep medicine. Required levels of knowledge and skills are defined, as is a proposed workload of 60 points according to the European Credit Transfer System (ECTS). The catalogue is intended to be a basis for sleep medicine education, for sleep medicine courses and for sleep medicine examinations, serving not only physicians with a medical speciality degree, but also PhD and MSc health professionals such as clinical psychologists and scientists, technologists and nurses, all of whom may be involved professionally in sleep medicine. In the future, the catalogue will be revised in accordance with advances in the field of sleep medicine. © 2013 European Sleep Research Society.

  19. Planck 2015 results. XXVI. The Second Planck Catalogue of Compact Sources

    CERN Document Server

    Ade, P.A.R.; Argueso, F.; Arnaud, M.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Banday, A.J.; Barreiro, R.B.; Bartolo, N.; Battaner, E.; Beichman, C.; Benabed, K.; Benoit, A.; Benoit-Levy, A.; Bernard, J.P.; Bersanelli, M.; Bielewicz, P.; Bock, J.J.; Bohringer, H.; Bonaldi, A.; Bonavera, L.; Bond, J.R.; Borrill, J.; Bouchet, F.R.; Boulanger, F.; Bucher, M.; Burigana, C.; Butler, R.C.; Calabrese, E.; Cardoso, J.F.; Carvalho, P.; Catalano, A.; Challinor, A.; Chamballu, A.; Chary, R.R.; Chiang, H.C.; Christensen, P.R.; Clemens, M.; Clements, D.L.; Colombi, S.; Colombo, L.P.L.; Combet, C.; Couchot, F.; Coulais, A.; Crill, B.P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R.D.; Davis, R.J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Desert, F.X.; Dickinson, C.; Diego, J.M.; Dole, H.; Donzelli, S.; Dore, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Ensslin, T.A.; Eriksen, H.K.; Falgarone, E.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A.A.; Franceschi, E.; Frejsel, A.; Galeotta, S.; Galli, S.; Ganga, K.; Giard, M.; Giraud-Heraud, Y.; Gjerlow, E.; Gonzalez-Nuevo, J.; Gorski, K.M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J.E.; Hansen, F.K.; Hanson, D.; Harrison, D.L.; Helou, G.; Henrot-Versille, S.; Hernandez-Monteagudo, C.; Herranz, D.; Hildebrandt, S.R.; Hivon, E.; Hobson, M.; Holmes, W.A.; Hornstrup, A.; Hovest, W.; Huffenberger, K.M.; Hurier, G.; Jaffe, A.H.; Jaffe, T.R.; Jones, W.C.; Juvela, M.; Keihanen, E.; Keskitalo, R.; Kisner, T.S.; Kneissl, R.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lahteenmaki, A.; Lamarre, J.M.; Lasenby, A.; Lattanzi, M.; Lawrence, C.R.; Leahy, J.P.; Leonardi, R.; Leon-Tavares, J.; Lesgourgues, J.; Levrier, F.; Liguori, M.; Lilje, P.B.; Linden-Vornle, M.; Lopez-Caniego, M.; Lubin, P.M.; Macias-Perez, J.F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Maris, M.; Marshall, D.J.; Martin, P.G.; Martinez-Gonzalez, E.; Masi, S.; Matarrese, S.; McGehee, P.; Meinhold, P.R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschenes, M.A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Murphy, J.A.; Naselsky, P.; Nati, F.; Natoli, P.; Negrello, M.; Netterfield, C.B.; Norgaard-Nielsen, H.U.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C.A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, T.J.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Pratt, G.W.; Prezeau, G.; Prunet, S.; Puget, J.L.; Rachen, J.P.; Reach, W.T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rowan-Robinson, M.; Rubino-Martin, J.A.; Rusholme, B.; Sandri, M.; Sanghera, H.S.; Santos, D.; Savelainen, M.; Savini, G.; Scott, D.; Seiffert, M.D.; Shellard, E.P.S.; Spencer, L.D.; Stolyarov, V.; Sudiwala, R.; Sunyaev, R.; Sutton, D.; Suur-Uski, A.S.; Sygnet, J.F.; Tauber, J.A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tornikoski, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Turler, M.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vielva, P.; Villa, F.; Wade, L.A.; Walter, B.; Wandelt, B.D.; Wehus, I.K.; Yvon, D.; Zacchei, A.; Zonca, A.

    2016-01-01

    The Second Planck Catalogue of Compact Sources is a catalogue of sources detected in single-frequency maps from the full duration of the Planck mission and supersedes previous versions of the Planck compact source catalogues. It consists of compact sources, both Galactic and extragalactic, detected over the entire sky. Compact sources detected in the lower frequency channels are assigned to the PCCS2, while at higher frequencies they are assigned to one of two sub-catalogues, the PCCS2 or PCCS2E, depending on their location on the sky. The first of these catalogues covers most of the sky and allows the user to produce subsamples at higher reliabilities than the target 80% integral reliability of the catalogue. The PCCS2E contains sources detected in sky regions where the diffuse emission makes it difficult to quantify the reliability of the detections. Both the PCCS2 and PCCS2E include polarization measurements, in the form of polarized flux densities, or upper limits, and orientation angles for all seven pol...

  20. Remapping simulated halo catalogues in redshift space

    OpenAIRE

    Mead, Alexander; Peacock, John

    2014-01-01

    We discuss the extension to redshift space of a rescaling algorithm, designed to alter the effective cosmology of a pre-existing simulated particle distribution or catalogue of dark matter haloes. The rescaling approach was initially developed by Angulo & White and was adapted and applied to halo catalogues in real space in our previous work. This algorithm requires no information other than the initial and target cosmological parameters, and it contains no tuned parameters. It is shown here ...

  1. Creation of Defects Catalogue for Nonconforming Product Identification in the Foundry Organization

    Directory of Open Access Journals (Sweden)

    Andrea Sütőová

    2013-12-01

    Full Text Available The paper deals with system of casting defects classification problematics and creation of defects catalogue in the foundry organization. There is described the value of correct defects classification and identification in the literature review and also some tools for defects classification are mentioned. Existing defects classifications and catalogues are often unusable for particular production processes and casting technology. Many foundries therefore create their own defects catalogues. The sample of created catalogue, which classifies and describes defects occuring in the aluminium foundry organization and its benefits are presented in the paper. The created catalogue primarily serves as a visual support for production operators and quality control processes.

  2. APOBEC3G Variants and Protection against HIV-1 Infection in Burkina Faso.

    Science.gov (United States)

    Compaore, Tegwinde Rebeca; Soubeiga, Serge Theophile; Ouattara, Abdoul Karim; Obiri-Yeboah, Dorcas; Tchelougou, Damehan; Maiga, Mamoudou; Assih, Maleki; Bisseye, Cyrille; Bakouan, Didier; Compaore, Issaka Pierre; Dembele, Augustine; Martinson, Jeremy; Simpore, Jacques

    2016-01-01

    Studies on host factors, particularly the APOBEC3G gene, have previously found an association with AIDS progression in some populations and against some HIV-1 strains but not others. Our study had two main objectives: firstly, to screen a population from Burkina Faso for three variants of APOBEC3G previously described, and secondly to analyze the effect of these three variants and their haplotypes on HIV-1 infection with Circulating Recombinant Forms (CRFs) present in Burkina Faso. This case control study involved 708 seropositive and seronegative individuals. Genotyping was done by the TaqMan allelic discrimination method. Minor allele frequencies of rs6001417 (p<0.05), rs8177832 (P<0.05), and rs35228531 (P<0.001) were higher in seronegative subjects. The rs6001417 and rs8177832 SNPs were associated with HIV-1 infection in an additive model (P<0.01). Furthermore the SNP rs35228531 was also associated with HIV-1 infection in a dominant model (P<0.001). Odds ratio analysis of genotypes and alleles of the different APOBEC3G variants showed that there is a strong association between the minor genetic variants, genotype of the three SNPs, and HIV-1 status. Haplotype analysis demonstrated that rs6001417, rs8177832, and rs35228531 are in linkage disequilibrium. The haplotype GGT from the rs6001417, rs8177832 and rs35228531 respectively has a protective effect OR = 0.54 [0.43-0.68] with P<0.001. There was also associations between the haplotypes GGC OR = 1.6 [1.1;-2.3] P<0.05, and CGC OR = 5.21 [2.4-11.3] P<0.001, which increase the risk of infection by HIV-1 from almost two (2) to five (5) fold. This study demonstrates an association of rs6001417, rs8177832, and rs35228531 of APOBEC3G with HIV-1 infection in a population from Burkina Faso.

  3. APOBEC3G Variants and Protection against HIV-1 Infection in Burkina Faso.

    Directory of Open Access Journals (Sweden)

    Tegwinde Rebeca Compaore

    Full Text Available Studies on host factors, particularly the APOBEC3G gene, have previously found an association with AIDS progression in some populations and against some HIV-1 strains but not others. Our study had two main objectives: firstly, to screen a population from Burkina Faso for three variants of APOBEC3G previously described, and secondly to analyze the effect of these three variants and their haplotypes on HIV-1 infection with Circulating Recombinant Forms (CRFs present in Burkina Faso. This case control study involved 708 seropositive and seronegative individuals. Genotyping was done by the TaqMan allelic discrimination method. Minor allele frequencies of rs6001417 (p<0.05, rs8177832 (P<0.05, and rs35228531 (P<0.001 were higher in seronegative subjects. The rs6001417 and rs8177832 SNPs were associated with HIV-1 infection in an additive model (P<0.01. Furthermore the SNP rs35228531 was also associated with HIV-1 infection in a dominant model (P<0.001. Odds ratio analysis of genotypes and alleles of the different APOBEC3G variants showed that there is a strong association between the minor genetic variants, genotype of the three SNPs, and HIV-1 status. Haplotype analysis demonstrated that rs6001417, rs8177832, and rs35228531 are in linkage disequilibrium. The haplotype GGT from the rs6001417, rs8177832 and rs35228531 respectively has a protective effect OR = 0.54 [0.43-0.68] with P<0.001. There was also associations between the haplotypes GGC OR = 1.6 [1.1;-2.3] P<0.05, and CGC OR = 5.21 [2.4-11.3] P<0.001, which increase the risk of infection by HIV-1 from almost two (2 to five (5 fold. This study demonstrates an association of rs6001417, rs8177832, and rs35228531 of APOBEC3G with HIV-1 infection in a population from Burkina Faso.

  4. Uniform Title in Theory and in Slovenian and Croatian Cataloguing Practice

    Directory of Open Access Journals (Sweden)

    Marija Petek

    2013-09-01

    Full Text Available ABSTRACTPurpose:  The paper investigates the importance and development of uniform title that enables collocation in the library catalogue. Research results on use of uniform titles in two union catalogues, the Slovenian COBISS and the Croatian CROLIST are also presented.Methodology/approach:  Theoretical apects of the uniform title are treated: for the first time by Panizzi, then in the Paris Principles being the basis for the Verona's cataloguing code; in the latest International Cataloguing Principles including conceptual models Functional Requirements for Bibliographic Records (FRBR and Functional Requirements for Authority Data (FRAD; and last but not least in the international cataloguing code Resource Description and Access (RDA. To find out whether the uniform titles are used consistently according to the Verona's cataloguing code and to the requirements of the bibliographic formats COMARC and UNIMARC, the frequency of tags 300 and 500 in bibliographic records is explored.Results:  The research results indicate that the use of uniform titles in COBISS and CROLIST is not satisfactory and that the tags 300 and 500 are often missing in bibliographic recods. In online catalogues a special attention should be given to the uniform title as it is considered an efficient linking device in the catalogue and as it enables collocation.Research limitations:  The research is limited to bibliographic records for translations of works of personal authors and of anonymous works; corporate authors are not included.Originality/practical implications:  Presenting development of the uniform title from the very beginning up to now and the first research on the uniform title in COBISS.

  5. Analysis of 23G and 25G+vitrectomy for retinal detachment

    Directory of Open Access Journals (Sweden)

    Ying-Li Lu

    2016-06-01

    Full Text Available AIM: To compare the clinical effect of 23G and 25G+ vitrectomy for retinal detachment. METHODS: Forty seven patients with retinal detachment were treated with 23G vitrectomy(27 eyes in 27 cases as group Aand 25G+ vitrectomy(20 eyes in 20 cases as group B. The operation time and the incidence of intraoperative complications were recorded. The occurrence of retinal reposition, visual acuity, intraocular pressure(IOPand complications were observed. Postoperative follow-up time of the two groups were 3d, 1wk, 3mo.The relevant records were statistically analyzed and compared. RESULTS: The operation time of 23G group and 25G+ group were 50.21+4.52min, 49.15+5.14min,respectively and there was no significant difference between the two groups(P>0.05. The main complications were retinal hemorrhage and iatrogenic retinal hole. There were 3 eyes with retinal hemorrhage, 2 eyes with iatrogenic retinal hole in 23G group, and 1 eye with retinal hemorrhage, 1 eye with iatrogenic retinal hole in the 25G+ group, and the difference was statistically significant(PP>0.05. The number of eyes with hypotonia in 23G and 25G+ group were 3 and 1 eyes respectively, the difference was statistically significant(PP>0.05. At the last follow-up, the results showed that 26 eyes(96%with retinal reposition in 23G group, 19 eyes(95%in 25G+ group, the difference was not statistically significant(P>0.05. CONCLUSION: The clinical effect of 23G and 25G+ vitrectomy for retinal detachment is similar, but 25G+ vitrectomy can reduce incidence of complications and early postoperative low IOP.

  6. Embeddings of SU/sup c/3 in unifying gauge groups

    International Nuclear Information System (INIS)

    Slansky, R.

    1978-01-01

    Hypothetical models that attempt to unify electromagnetic, weak, and strong interactions into a simple, compact gauge group G are discussed. The problem of embedding the strong group SU 3 /sup c/ in any larger simple group is solved, and a complete classification of theories where the color in some representation is restricted to 1/sup c/, 3/sup c/, and anti 3/sup c/ is given

  7. Light-induced translocation of Pyronine G from mitochondria to nucleoli in monkey kidney CV-1 cells

    Science.gov (United States)

    Geze, Marc; Dellinger, M.; Bazin, M.; Santus, Rene C.

    1996-12-01

    Pyronine G (3,6-bis-N,N-dimethylaminoxanthylium chloride; PG) is a cationic dye that concentrates in mitochondria of living cells due to the high membrane potential of these organelles, similarly to rhodamine 123 and many other cationic dyes. Pyronine G also shows a preferential affinity for RNA. Upon light irradiation PG has been shown to induce cell death, but the photosensitizing properties of this molecule and the mechanism of cell death are not well understood. Microfluorometry and most particularly microspectrofluorometry are now powerful non-invasive techniques for quantitative studies of single living cells in real time which allow, for example, knowing how living cells are affected by photosensitization. To demonstrate the usefulness of image acquisition with high resolution and high sensitive camera, we present data on photosensitizer relocalization during illumination leading to functional and structural damage in the cells.

  8. 26 CFR 1.1366-3 - Treatment of family groups.

    Science.gov (United States)

    2010-04-01

    ... more shareholders of the S corporation holds an interest in a passthrough entity (e.g., a partnership... (CONTINUED) INCOME TAXES Small Business Corporations and Their Shareholders § 1.1366-3 Treatment of family... more shareholders of an S corporation, renders services for, or furnishes capital to, the corporation...

  9. PAI-1 mRNA expression and plasma level in rheumatoid arthritis: relationship with 4G/5G PAI-1 polymorphism.

    Science.gov (United States)

    Muñoz-Valle, José Francisco; Ruiz-Quezada, Sandra Luz; Oregón-Romero, Edith; Navarro-Hernández, Rosa Elena; Castañeda-Saucedo, Eduardo; De la Cruz-Mosso, Ulises; Illades-Aguiar, Berenice; Leyva-Vázquez, Marco Antonio; Castro-Alarcón, Natividad; Parra-Rojas, Isela

    2012-12-01

    Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting the synovial membrane, cartilage and bone. PAI-1 is a key regulator of the fibrinolytic system through which plasminogen is converted to plasmin. The plasmin activates the matrix metalloproteinase system, which is closely related with the joint damage and bone destruction in RA. The aim of this study was to investigate the relationship between 4G/5G PAI-1 polymorphism with mRNA expression and PAI-1 plasma protein levels in RA patients. 113 RA patients and 123 healthy subjects (HS) were included in the study. The 4G/5G PAI-1 polymorphism was determined by polymerase chain reaction-restriction fragment length polymorphism method; the PAI-1 mRNA expression was determined by real-time PCR; and the soluble PAI-1 (sPAI-1) levels were quantified using an ELISA kit. No significant differences in the genotype and allele frequencies of 4G/5G PAI-1 polymorphism were found between RA patients and HS. However, the 5G/5G genotype was the most frequent in both studied groups: RA (42%) and HS (44%). PAI-1 mRNA expression was slightly increased (0.67 fold) in RA patients with respect to HS (P = 0.0001). In addition, in RA patients, the 4G/4G genotype carriers showed increased PAI-1 mRNA expression (3.82 fold) versus 4G/5G and 5G/5G genotypes (P = 0.0001), whereas the sPAI-1 plasma levels did not show significant differences. Our results indicate that the 4G/5G PAI-1 polymorphism is not a marker of susceptibility in the Western Mexico. However, the 4G/4G genotype is associated with high PAI-1 mRNA expression but not with the sPAI-1 levels in RA patients.

  10. The Limbic-Prefrontal Network Modulated by Electroacupuncture at CV4 and CV12

    Directory of Open Access Journals (Sweden)

    Jiliang Fang

    2012-01-01

    Full Text Available fMRI studies showed that acupuncture could induce hemodynamic changes in brain networks. Many of these studies focused on whether specific acupoints could activate specific brain regions and were often limited to manual acupuncture at acupoints on the limbs. In this fMRI study, we investigated acupuncture's modulation effects on brain functional networks by electroacupuncture (EA at acupoints on the midline of abdomen. Acupoints Guanyuan (CV4 and Zhongwan (CV12 were stimulated in 21 healthy volunteers. The needling sensations, brain activation, and functional connectivity were studied. We found that the limbic-prefrontal functional network was deactivated by EA at CV4 and CV12. More importantly, the local functional connectivity was significantly changed during EA stimulation, and the change persisted during the period after the stimulation. Although minor differences existed, both acupoints similarly modulated the limbic-prefrontal functional network, which is overlapped with the functional circuits associated with emotional and cognitive regulation.

  11. Aminoethoxivinilglicina no controle do amadurecimento de frutos de caqui cv. Fuyu Aminoethoxyvinylglycine in the ripening control of persimmon fruits cv. Fuyu

    Directory of Open Access Journals (Sweden)

    Angela Fuentes Fagundes

    2006-04-01

    Full Text Available Objetivou-se avaliar o efeito de aminoethoxivinilglicina (AVG, aplicado na pós-colheita, no amadurecimento de frutos de caqui (Diospyros kaki L. cv. Fuyu, armazenados à temperatura de 0 ± 2 ºC. Os frutos foram imersos durante dois minutos em solução de AVG, na concentração de 0; 415; 830 e 1.200 g ha-1 e dissolvidos em água destilada e adição de espalhante adesivo (óleo vegetal a 0,02% (v/v, secos à temperatura ambiente no barracão e armazenados em câmara fria a 0 ± 2 ºC e 95±2 % UR, e avaliados aos 32 e 52 dias com relação à firmeza, sólidos solúveis, pH da polpa, acidez titulável e injúria por frio. O AVG mostrou-se promissor no uso pós-colheita em caqui, onde os frutos tratados conservaram índices de firmeza linear em função da dose e teores de AT, SS e pH aceitáveis para o 'Fuyu'. Porém os frutos apresentaram translucidez, característica de injúria por frio, indicando a necessidade de novos estudos para se compreender a fisiologia pós-colheita deste fruto.An experiment was carried out to analyze the effect of the application of Aminoethoxyvinylglycine (AVG in post harvest application in persimmon fruits (Diospyros kaki L. cv. Fuyu stored at a temperature of 0 ± 2ºC. The fruits were immersed for two minutes into an AVG solution at a concentration of 0; 415; 830; 1200 g ha-1 and dissolved in distillated water. Then it was added adhesive spreader (vegetable oil 0.02% (v/v, dried at room temperature and stored at 0 ± 2 ºC and 95±2 % humidity. The treatments were evaluated on the 32nd and 52nd days to check the firmness, soluble solids, pH of the pulp, tritable acidity and chilling injury. The AVG may be promising in post harvest use with persimmon fruits, where treated fruits preserved linear levels of firmness in function of the doses and TA, SS and pH levels are acceptable for cv. Fuyu. However, fruits showed translucency, which are characteristics of chilling injury, indicating that new studies are

  12. Remapping dark matter halo catalogues between cosmological simulations

    Science.gov (United States)

    Mead, A. J.; Peacock, J. A.

    2014-05-01

    We present and test a method for modifying the catalogue of dark matter haloes produced from a given cosmological simulation, so that it resembles the result of a simulation with an entirely different set of parameters. This extends the method of Angulo & White, which rescales the full particle distribution from a simulation. Working directly with the halo catalogue offers an advantage in speed, and also allows modifications of the internal structure of the haloes to account for non-linear differences between cosmologies. Our method can be used directly on a halo catalogue in a self-contained manner without any additional information about the overall density field; although the large-scale displacement field is required by the method, this can be inferred from the halo catalogue alone. We show proof of concept of our method by rescaling a matter-only simulation with no baryon acoustic oscillation (BAO) features to a more standard Λ cold dark matter model containing a cosmological constant and a BAO signal. In conjunction with the halo occupation approach, this method provides a basis for the rapid generation of mock galaxy samples spanning a wide range of cosmological parameters.

  13. Chest Compressions during Sustained Inflations Improve Recovery When Compared to a 3:1 Compression:Ventilation Ratio during Cardiopulmonary Resuscitation in a Neonatal Porcine Model of Asphyxia.

    Science.gov (United States)

    Li, Elliott S; Görens, Immanuel; Cheung, Po-Yin; Lee, Tze-Fun; Lu, Min; O'Reilly, Megan; Schmölzer, Georg M

    2017-01-01

    Recently, sustained inflations (SI) during chest compression (CC) (CC+SI) have been suggested as an alternative to the current approach during neonatal resuscitation. No previous study compared CC+SI using CC rates of 90/min to the current 3:1 compression:ventilation ratio (C:V). To determine whether CC+SI versus a 3:1 C:V reduces the time to the return of spontaneous circulation (ROSC) and improves hemodynamic recovery in newborn piglets with asphyxia-induced bradycardia. Term newborn piglets were anesthetized, intubated, instrumented, and exposed to 45-min normocapnic hypoxia followed by asphyxia. Cardiopulmonary resuscitation (CPR) was initiated when the heart rate decreased to 25% of baseline. Piglets were randomized into 3 groups: CC during SI at a rate of 90 CC/min (SI+CC 90, n = 8), a 3:1 C:V using 90 CC and 30 inflations (3:1, n = 8), or a sham group (n = 6). Cardiac function, carotid blood flow, cerebral oxygenation, and respiratory parameters were continuously recorded throughout the experiment. CC+SI significantly reduced the median (IQR) time of ROSC, i.e., 34 s (28-156 s) versus 210 s (72-300 s) in the 3:1 group (p = 0.048). CC+SI also significantly reduced the requirement for 100% oxygen, improved respiratory parameters, and resulted in a similar hemodynamic recovery. CC+SI during CPR significantly improved ROSC in a porcine model of neonatal resuscitation. This is of considerable clinical relevance because improved respiratory and hemodynamic parameters potentially minimize morbidity and mortality in newborn infants. © 2017 S. Karger AG, Basel.

  14. HER-2 immunohistochemical expression as prognostic marker in high-grade T1 bladder cancer (T1G3

    Directory of Open Access Journals (Sweden)

    Luca Bongiovanni

    2013-06-01

    Full Text Available Objectives: To evaluate if the Human epidermal growth factor receptor 2 (HER-2 expression levels may be used as potential prognostic marker in high grade T1 blad- der cancer (T1G3 Methods: Specimens from transurethral resection of bladder tumour (TURBT of 103 patients with high-grade T1 bladder cancer were collected. This pathologic database was reviewed. Four-year follow-up data were matched with pathologic data. Eighty-three patients entered the study. HER-2 staining was performed. Patients were grouped for HER-2 status. Statistical analysis included Kaplan Meier survival analysis and Log-rank test. Results: Pathological review of TURBT specimens confirmed high-grade T1 transitional cell bladder cancer in all patients. Median follow-up was 12 months (mean 23,5; range 3-48. Twenty-one patients (25.4% present strong HER-2 expression (3+, 28 (33.7% moderate expression (2+, 26 (33.7% weak staining (1+ and 8 (9.6% negative expression (0. Thirty- one patients of 83 (37.4% had not evidence of disease, 41 (49.4% recurred, 11 (13.2% had a progression of disease. Forty-one patients had high grade T1 recurrence. Patients with HER-2 status 0 did not showed progression of disease. Patients with HER-2 status 3+, undergoing cys- tectomy because progression of disease, had a pathological stage > pT2 and a nodal involve- ment. Median Disease-Free Survival (DFS for all patients was 12 months (DFS probability (pDFS = 49.3%; 95% CI, -11.1/+10.1. Median DFS in HER-2 groups was 8 (pDFS 37.5%; 95% CI,-28.8/+29.9, 24 (pDFS 46.1%; 95% CI,-19.5/+17.5, 20 (pDFS 46.4%; 95% CI,-18.8/+16.9 and 10 months (pDFS 47.6%; 95% CI,-21.9/+19.1 respectively in HER-2 status 0,1+,2+,3+. Log-Rank test is not statistically significant (p = 0,39. Conclusions: This study showed that HER-2 expression does not represent a prognostic mark- er of recurrence/progression of disease in high-grade T1 bladder cancer.

  15. A human repair gene ERCC5 is involved in group G xeroderma pigmentosum

    International Nuclear Information System (INIS)

    Shiomi, Tadahiro

    1994-01-01

    In E. coli, ultraviolet-induced DNA damage is removed by the coordinated action of UVR A, B, C, and D proteins (1). In Saccharomyces cerevisiae, more than ten genes have been reported to be involved in excision repair (2). The nucleotide excision repair pathway has been extensively studied in these organisms. To facilitate studying nucleotide excision repair in mammalian cells. Ultraviolet-sensitive rodent cell mutants have been isolated and classified into 11 complementation groups (9,10). The human nucleotide excision repair genes which complement the defects of the mutants have been designated as the ERCC (excision repair cross-complementing) genes; a number is added to refer to the particular rodent complementation group that is corrected by the gene. Recently, several human DNA repair genes have been cloned using rodent cell lines sensitive to ultraviolet. These include ERCC2 (3), ERCC3 (4), and ERCC6 (5), which correspond to the defective genes in the ultraviolet-sensitive human disorders xeroderma pigmentosum (XP) group D (6) and group B (4), and Cockayne's syndrome (CS) group B (7), respectively. The human excision repair gene ERCC5 was cloned after DNA-mediated gene transfer of human HeLa cell genomic DNA into the ultraviolet-sensitive mouse mutant XL216, a member of rodent complementation group 5 (11,12) and the gene was mapped on human chromosome 13q32.3-q33.1 by the replication R-banding fluorescence in situ hybridization method (13). The ERCC5 cDNA encodes a predicted 133 kDa nuclear protein that shares some homology with product of the yeast DNA repair gene RAD 2. Transfection with mouse ERCC5 cDNA restored normal levels of ultraviolet-resistance to XL216 cells. Microinjection of ERCC5 cDNA specifically restored the defect of XP group G cells (XP-G) as measured by unscheduled DNA synthesis (UDS), and XP-G cells stably transformed with ERCC5 cDNA showed nearly normal ultraviolet resistance. (J.P.N.)

  16. Planck 2015 results: XXVIII. The Planck Catalogue of Galactic cold clumps

    DEFF Research Database (Denmark)

    Ade, P. A R; Aghanim, N.; Arnaud, M.

    2016-01-01

    We present the Planck Catalogue of Galactic Cold Clumps (PGCC), an all-sky catalogue of Galactic cold clump candidates detected by Planck. This catalogue is the full version of the Early Cold Core (ECC) catalogue, which was made available in 2011 with the Early Release Compact Source Catalogue (E...

  17. NONUNIFORM EXPANSION OF THE YOUNGEST GALACTIC SUPERNOVA REMNANT G1.9+0.3

    International Nuclear Information System (INIS)

    Borkowski, Kazimierz J.; Reynolds, Stephen P.; Green, David A.; Hwang, Una; Petre, Robert; Krishnamurthy, Kalyani; Willett, Rebecca

    2014-01-01

    We report measurements of the X-ray expansion of the youngest Galactic supernova remnant, G1.9+0.3, using Chandra observations in 2007, 2009, and 2011. The measured rates strongly deviate from uniform expansion, decreasing radially by about 60% along the X-ray bright SE-NW axis from 0.84% ± 0.06% yr –1 to 0.52% ± 0.03% yr –1 . This corresponds to undecelerated ages of 120-190 yr, confirming the young age of G1.9+0.3 and implying a significant deceleration of the blast wave. The synchrotron-dominated X-ray emission brightens at a rate of 1.9% ± 0.4% yr –1 . We identify bright outer and inner rims with the blast wave and reverse shock, respectively. Sharp density gradients in either the ejecta or ambient medium are required to produce the sudden deceleration of the reverse shock or the blast wave implied by the large spread in expansion ages. The blast wave could have been decelerated recently by an encounter with a modest density discontinuity in the ambient medium, such as may be found at a wind termination shock, requiring strong mass loss in the progenitor. Alternatively, the reverse shock might have encountered an order-of-magnitude density discontinuity within the ejecta, such as may be found in pulsating delayed-detonation Type Ia models. We demonstrate that the blast wave is much more decelerated than the reverse shock in these models for remnants at ages similar to G1.9+0.3. Similar effects may also be produced by dense shells possibly associated with high-velocity features in Type Ia spectra. Accounting for the asymmetry of G1.9+0.3 will require more realistic three-dimensional Type Ia models

  18. Efeito de substrato artificial no enraizamento de estacas de calanchoe (Kalanchoe x blossfeldiana cv. singapur, crassulaceae Artificial substract effect on the rooting of calanchoe (Kalanchoe x blossfeldiana cv. singapur, crassulaceae cuttings

    Directory of Open Access Journals (Sweden)

    A.L. Gonçalves

    1994-08-01

    Full Text Available Dez misturas artificiais foram estudadas para avaliar o efeito sobre o enraizamento de estacas apicais de Kalanchoe x blossfeldiana cv. Singapur, da família Crassulaceae. Essas misturas foram as seguintes: vermiculita + casca de arroz tostada nas proporções 1:1, 2:1 e 3:1; vermiculita + torta de filtro Oliver nas proporções 1:1, 2:1 e 3:1; vermiculita + turfa da região de Atibaia-SP, nas proporções 1:l, 2:le3:l; vermiculita + casca de pinheiro (mistura comercial. Os melhores resultados foram obtidos com a mistura vermiculita + torta de filtro Oliver em todas as proporções, vermiculita + casca de arroz tostada 3:1 e vermiculita + turfa 3:1. Os piores desempenhos foram os das misturas vermiculita + casca de pinheiro e vermiculita + turfa 1:1.Ten different artificial mixtures were studied as rooting media for Kalanchoe x blossfeldiana cv. Singapur cuttings. They were: vermiculite + toasted rice hulls (1:1, 2:1, 3:1; vermiculite + Oliver filter cake (1:1, 2:1, 3:1; vermiculite + peat (1:1, 2:1, 3:1; and vermiculite + pine bark (commercial mixture. The best results were observed for vermiculite + Oliver filter cake (1:1, 2:1, 3:1, vermiculite + toasted rice hulls (3:1 and vermiculite + peat (3:1. The worst results were observed with vermiculite + pine bark and vermiculite + peat (1:1.

  19. Australian comments on data catalogues

    Energy Technology Data Exchange (ETDEWEB)

    Symonds, J L [A.A.E.C. Research Establishment, Lucas Heights (Australia)

    1968-05-01

    Between the need for some neutron data and a final evaluated set of data, the need for an action file, a bibliographic and reference file of catalogue, and a data storage and retrieval file is discussed.

  20. Generation and characterization of APOBEC3G-positive 293T cells for HIV-1 Vif study

    OpenAIRE

    Piroozmand, Ahmad; Yamamoto, Yoshihiko; Khamsri, Boonruang; Fujita, Mikako; Uchiyama, Tsuneo; Adachi, Akio

    2007-01-01

    We have established a number of 293T cell lines that express a human anti HIV-1 factor APOBEC3G. Out of seven cell clones examined, four were readily demonstrated to express APOBEC3G by immunoblotting analysis. In particular, two clones (A3G-C1 and -C4) were found to produce a much higher level of functional APOBEC3G relative to that by pooled cell clones. The transfection efficiency of all these cell clones were similar to that of the parental cells, producing a comparable level of virions u...

  1. Ablation of PPP1R3G reduces glycogen deposition and mitigates high-fat diet induced obesity.

    Science.gov (United States)

    Zhang, Yongxian; Gu, Jin; Wang, Lin; Zhao, Zilong; Pan, Yi; Chen, Yan

    2017-01-05

    Glycogen and triglyceride are two major forms of energy storage in the body and provide the fuel during different phases of food deprivation. However, how glycogen metabolism is linked to fat deposition in adipose tissue has not been clearly characterized. We generated a mouse model with whole-body deletion of PPP1R3G, a glycogen-targeting subunit of protein phosphatase-1 required for glycogen synthesis. Upon feeding with high-fat diet, the body weight and fat composition are significantly reduced in the PPP1R3G -/- mice compared to the wild type controls. The metabolic rate of the mice as measured by O 2 consumption and CO 2 production is accelerated by PPP1R3G deletion. The high-fat diet-induced liver steatosis is also slightly relieved by PPP1R3G deletion. The glycogen level in adipose tissue is reduced by PPP1R3G deletion. In 3T3L1 cells, overexpression of PPP1R3G leads to increases of both glycogen and triglyceride levels. In conclusion, our study indicates that glycogen is actively involved in fat accumulation in adipose tissue and obesity development upon high-fat diet. Our study also suggests that PPP1R3G is an important player that links glycogen metabolism to lipid metabolism in vivo. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  2. Catalogue of Positions and Proper Motions of Stars in the Vicinity of Open Clusters

    Directory of Open Access Journals (Sweden)

    Protsyuk, Yu.I.

    2017-01-01

    Full Text Available In the Research Institute Mykolaiv Astronomical Observatory (MAO the catalogue of position and proper motions of stars in the 544 square areas of nearly (1×1°around the Galactic open clusters was created using photographic and CCD observations. 293 plates of (5×5°obtained with the MAO Zonal Astrograph (D=116 mm, F=2040 mm in 1962-1993 and more than 20 thousands CCD frames (0.7×0.7° obtained with KT-50 telescope (D=500 mm, F=3000 mm in 2011-2015 were used. Almost 270 thousands FITS files from the IVOA image archives with observational epoch from 1953 to 2010 were downloaded and processed. The created catalogue contains more than 2.3 million stars (7.5-18.5m in the ICRS system with the accuracy of positions on both coordinates ranged from 0.02" to 0.05". Inner accuracy of proper motions is ~0.004"/year.

  3. 123 I production using CV-28 cyclotron from IPEN-CNEN/SP

    International Nuclear Information System (INIS)

    Mestnik, S.A.C.; Mengatti, J.; Nieto, W.; Yanagawa, S.I.; Sumiya, L.C.A.; Silva, C.P.G.; Osso Junior, J.A.

    1992-01-01

    The main conditions for iodine 123 production by 124 Te (p,2 n) 123 I reaction were presented, using the cyclotron CV-28 at IPEN-CNEN/SP, with protons of E max = 24 MeV. Two types of targets (Te O 2 and Te O 2 + 2% Al 2 O 3 ) and the influence of Al 2 O 3 in iodine release were studied. After the selection, the 124 Te O 2 (96,2%) target, was melted in platinum support and irradiated with proton current until 12 mu A. The separation of 123 I was made by dry distillation, using induction furnace and O 2 atmosphere. (C.G.C.)

  4. Plasminogen activator inhibitor-1 4G/5G polymorphism, factor V Leiden, prothrombin mutations and the risk of VTE recurrence.

    Science.gov (United States)

    Sundquist, Kristina; Wang, Xiao; Svensson, Peter J; Sundquist, Jan; Hedelius, Anna; Larsson Lönn, Sara; Zöller, Bengt; Memon, Ashfaque A

    2015-11-25

    Plasminogen-activator inhibitor (PAI)-1 is an important inhibitor of the plasminogen/plasmin system. PAI-1 levels are influenced by the 4G/5G polymorphism in the PAI-1 promoter. We investigated the relationship between the PAI-1 polymorphism and VTE recurrence, and its possible modification by factor V Leiden (FVL) and prothrombin (PTM) mutations. Patients (n=1,069) from the Malmö Thrombophilia Study were followed from discontinuation of anticoagulant treatment until diagnosis of VTE recurrence or the end of the study (maximum follow-up 9.8 years). One hundred twenty-seven patients (11.9 %) had VTE recurrence. PAI-1 was genotyped by TaqMan PCR. Cox regression analysis adjusted for age, sex and acquired risk factors of VTE showed no evidence of an association between PAI-1 genotype and risk of VTE recurrence in the study population as a whole. However, by including an interaction term in the analysis we showed that FVL but not PTM modified the effect of PAI-1 genotype: patients with the 4G allele plus FVL had a higher risk of VTE recurrence [hazard ratio (HR) =2.3, 95 % confidence interval (CI) =1.5-3.3] compared to patients with the 4G allele but no FVL (reference group) or FVL irrespective of PAI-1 genotype (HR=1.8, 95 % CI=1.3-2.5). Compared to reference group, 5G allele irrespective of FVL was associated with lower risk of VTE recurrence only when compared with 4G allele together with FVL. In conclusion, FVL has a modifying effect on PAI-1 polymorphism in relation to risk of VTE recurrence. The role of PAI-1 polymorphism as a risk factor of recurrent VTE may be FVL dependent.

  5. Assessing the catalogue module of Alice for window software ...

    African Journals Online (AJOL)

    The paper presents a general description of Alice For Window Software with a detailed analysis of the catalogue module. It highlights the basic features of the module such as add, edit, delete, search field and the grab button. The cataloguing process is clearly delineated. The paper also discusses Alice For Window ...

  6. Features, events and processes evaluation catalogue for argillaceous media

    International Nuclear Information System (INIS)

    Mazurek, M.; Pearson, F.J.; Volckaert, G.; Bock, H.

    2003-01-01

    The OECD/NEA Working Group on the Characterisation, the Understanding and the Performance of Argillaceous Rocks as Repository Host Formations for the disposal of radioactive waste (known as the 'Clay Club') launched a project called FEPCAT (Features, Events and Processes Catalogue for argillaceous media) in late 1998. The present report provides the results of work performed by an expert group to develop a FEPs database related to argillaceous formations, whether soft or indurated. It describes the methodology used for the work performed, provides a list of relevant FEPs and summarises the knowledge on each of them. It also provides general conclusions and identifies priorities for future work. (authors)

  7. MKP1 phosphatase mediates G1-specific dephosphorylation of H3Serine10P in response to DNA damage

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, Ajit K.; Khan, Shafqat A.; Sharda, Asmita; Reddy, Divya V; Gupta, Sanjay, E-mail: sgupta@actrec.gov.in

    2015-08-15

    Highlights: • Reversible reduction of H3S10 phosphorylation after DNA damage is G1 phase specific. • Dynamic balance between MAP kinases, MKP1 and MSK1 regulate H3S10P during DDR. • MKP1 associates with chromatin bearing γH2AX in response to DNA damage. • Inhibition of MKP1 activity with specific inhibitor promotes radiation-induced cell death. - Abstract: Histone mark, H3S10 phosphorylation plays a dual role in a cell by maintaining relaxed chromatin for active transcription in interphase and condensed chromatin state in mitosis. The level of H3S10P has also been shown to alter on DNA damage; however, its cell cycle specific behavior and regulation during DNA damage response is largely unexplored. In the present study, we demonstrate G1 cell cycle phase specific reversible loss of H3S10P in response to IR-induced DNA damage is mediated by opposing activities of phosphatase, MKP1 and kinase, MSK1 of the MAP kinase pathway. We also show that the MKP1 recruits to the chromatin in response to DNA damage and correlates with the decrease of H3S10P, whereas MKP1 is released from chromatin during recovery phase of DDR. Furthermore, blocking of H3S10 dephosphorylation by MKP1 inhibition impairs DNA repair process and results in poor survival of WRL68 cells. Collectively, our data proposes a pathway regulating G1 cell cycle phase specific reversible reduction of H3S10P on IR induced DNA damage and also raises the possibility of combinatorial modulation of H3S10P with specific inhibitors to target the cancer cells in G1-phase of cell cycle.

  8. Evaluation of past and future alterations in tuff at Yucca Mountain, Nevada, based on the clay mineralogy of drill cores USW G-1, G-2, and G-3

    International Nuclear Information System (INIS)

    Bish, D.L.

    1989-03-01

    The tuffs at Yucca Mountain in south-central Nevada are being studied by the Yucca Mountain Project (YMP) to determine their suitability for a high-level radioactive waste repository. For predictive purposes, it is important to understand the alteration history of Yucca Mountain and to know how the minerals in Yucca Mountain tuffs respond to changing conditions such as elevated temperatures. The clay mineralogy of these tuffs has been examined using x-ray powder diffraction, and approximation temperatures of alteration have been determined using available clay mineral data and fluid inclusion analyses. Also, several illites from drill holes USW G-1 and G-2 have been dated using K/Ar techniques, yielding ages of about 11 Myr. The clay mineral in Yucca Mountain tuffs are predominantly interstratified illite/smectites, with minor amounts of chloride, kaolinite, and interstratified chlorite/smectite at depth in USW G-1 and G-2. The reactions observed for these illite/smectites are similar to those observed in pelitic rocks. With depths, the illite/smectites transform from random interstratifications (R = 0) through ordered intermediates (R = 1) to illite in USW G-2 and to Kalkberg (R ≥ 3) interstratifications in USW G-1. The illite/smectites in USW G-3 have not significantly transformed. It appears that the illites in deeper rock results from hydrothermal and diagenetic reactions of earlier-formed smectites. These data demonstrate that the rocks at depth in the northern end of Yucca Mountain were significantly altered about 11 Myr ago. Both clay mineralogy and fluid inclusions suggest that the rocks at depth in USW G-2 have been subjected to postdepositional temperatures of at least 275/degree/C, those in USW G-1 have reached 200/degree/C, and USW G-3 rocks probably have not exceeded 100/degree/C. 64 refs., 9 figs., 3 tabs

  9. An Equivalent Moment Magnitude Earthquake Catalogue for Western Turkey and its Quantitative Properties

    Science.gov (United States)

    Leptokaropoulos, Konstantinos; Vasilios, Karakostas; Eleftheria, Papadimitriou; Aggeliki, Adamaki; Onur, Tan; Zumer, Pabuçcu

    2013-04-01

    technique introduced in this study may constitute a useful tool for future seismicity research in Western Turkey. Acknowledgements: This work was partially supported by the research project titled as "Seismotectonic properties of the eastern Aegean: Implications on the stress field evolution and seismic hazard assessment in a tectonically complex area", GSRT 10 T UR/ 1-3-9, Joint Research and Technology Programmes 2010 - 2011, financed by the Ministry of Education of Greece.

  10. Non-CpG methylation of the PGC-1alpha promoter through DNMT3B controls mitochondrial density

    DEFF Research Database (Denmark)

    Barres, Romain; Osler, Megan E; Yan, Jie

    2009-01-01

    -CpG nucleotides. Non-CpG methylation was acutely increased in human myotubes by exposure to tumor necrosis factor-alpha (TNF-alpha) or free fatty acids, but not insulin or glucose. Selective silencing of the DNA methyltransferase 3B (DNMT3B), but not DNMT1 or DNMT3A, prevented palmitate-induced non......-CpG methylation of PGC-1alpha and decreased mtDNA and PGC-1alpha mRNA. We provide evidence for PGC-1alpha hypermethylation, concomitant with reduced mitochondrial content in type 2 diabetic patients, and link DNMT3B to the acute fatty-acid-induced non-CpG methylation of PGC-1alpha promoter....

  11. [Induced expression of Serratia marcescens ribonuclease III gene in transgenic Nicotiana tabacum L. cv. SR1 tobacco plants].

    Science.gov (United States)

    Zhirnov, I V; Trifonova, E A; Romanova, A V; Filipenko, E A; Sapotsky, M V; Malinovsky, V I; Kochetov, A V; Shumny, V K

    2016-11-01

    Transgenic Nicotiana tabacum L. cv. SR1 plants, characterized by an increase in the level of dsRNA-specific hydrolytic activity after induction by wounding, were obtained. The Solanum lycopersicum anionic peroxidase gene promoter (new for plant genetic engineering) was for the first time used for the induced expression of the target Serratia marcescens RNase III gene. Upon infection with the tobacco mosaic virus (TMV), the transgenic plants of the obtained lines did not differ significantly from the control group in the level of TMV capsid protein accumulation. In general, no delay in the development of the infection symptoms was observed in transgenic plants as compared with the control group. The obtained transgenic plants represent a new model for the study of the biological role of endoribonucleases from the RNase III family, including in molecular mechanisms of resistance to pathogens.

  12. Profile catalogue for airfoil sections based on 3D

    Energy Technology Data Exchange (ETDEWEB)

    Bertagnolio, F.; Soerensen, Niels N.; Johansen, Jeppe

    2006-12-15

    This report is a continuation of the Wind Turbine Airfoil Catalogue which objective was, firstly to provide a database of aerodynamic characteristics for a wide range of airfoil profiles aimed at wind turbine applications, and secondly to test the two-dimensional Navier-Stokes solver EllipSys2D by comparing its results with experimental data. In the present work, the original two-dimensional results are compared with three-dimensional calculations as it was surmised that the two-dimensional assumption might be in some cases responsible for discrepancies between the numerical flow solution and the actual fluid flow, and thereby the incorrect prediction of airfoil characteristics. In addition, other features of the flow solver, such as transition and turbulence modelling, and their influence onto the numerical results are investigated. Conclusions are drawn regarding the evaluation of airfoil aerodynamic characteristics, as well as the use of the Navier-Stokes solver for fluid flow calculations in general. (au)

  13. Immediate Effect of Needling at CV-12 (Zhongwan) Acupuncture Point on Blood Glucose Level in Patients with Type 2 Diabetes Mellitus: A Pilot Randomized Placebo-Controlled Trial.

    Science.gov (United States)

    Kumar, Ranjan; Mooventhan, A; Manjunath, Nandi Krishnamurthy

    2017-08-01

    Diabetes mellitus is a major global health problem. Needling at CV-12 has reduced blood glucose level in diabetic rats. The aim of this study was to evaluate the effect of needling at CV-12 (Zhongwan) on blood glucose level in patients with type 2 diabetes mellitus (T2DM). Forty T2DM patients were recruited and randomized into either the acupuncture group or placebo control group. The participants in the acupuncture group were needled at CV-12 (4 cun above the center of the umbilicus), and those in the placebo control group were needled at a placebo point on the right side of the abdomen (1 cun beside the CV-12). For both groups, the needle was retained for 30 minutes. Assessments were performed prior to and after the intervention. Statistical analysis was performed using SPSS version 16. There was a significant reduction in random blood glucose level in the acupuncture group compared to baseline. No such significant change was observed in the placebo control group. The result of this study suggests that 30 minutes of needling at CV-12 might be useful in reducing blood glucose level in patients with T2DM. Copyright © 2017. Published by Elsevier B.V.

  14. Expression of transcription factors after short-term exposure of Arabidopsis thaliana cell cultures to hyper-g, and to simulated and sounding rocket micro-g

    Science.gov (United States)

    Hampp, R.; Babbick, M.

    Previous microarray studies with cell cultures of Arabidopsis thaliana cv Columbia have shown responses in gene expression which were partly specific to exposure to microgravity sounding rocket experiment TEXUS In order to get access to early responses upon changes in gravitational fields we used exposure times as short as 2 min For this purpose we selected a range of genes which code for different groups of transcription factors WRKY ERF MYB MADS Samples were taken in 5-min clinorotation 2- and 3-dimensional hypergravity 8g and 2-min intervals sounding rocket experiment Amounts of transcripts were determined by quantitative RT PCR Most transcripts showed a significant transient change in content within a time frame of up to 30 min after changing the external gravitational field strength They could be grouped into 1 basic stress responses which occurred under all conditions 2 clinorotation-related effects which were either identical or opposite between 2D 60 rpm 4x10 -2 g and 3D clinorotation random positioning machine and 3 alterations specific to the microgravity exposure under sounding rocket conditions MAXUS The data are discussed in relation to gravitation-dependent signalling chains and with regard to the simulation of microgravity by means of clinorotation Supported by a grant from the Deutsches Zentrum f u r Luft- und Raumfahrt e V grant no 50 WB 0143

  15. Tomographic local 2D analyses of the WISExSuperCOSMOS all-sky galaxy catalogue

    Science.gov (United States)

    Novaes, C. P.; Bernui, A.; Xavier, H. S.; Marques, G. A.

    2018-05-01

    The recent progress in obtaining larger and deeper galaxy catalogues is of fundamental importance for cosmological studies, especially to robustly measure the large scale density fluctuations in the Universe. The present work uses the Minkowski Functionals (MF) to probe the galaxy density field from the WISExSuperCOSMOS (WSC) all-sky catalogue by performing tomographic local analyses in five redshift shells (of thickness δz = 0.05) in the total range of 0.10 methodology reveals 1 - 3 regions of the GNC maps in each redshift shell with an uncommon behaviour (extreme regions), i.e., p-value < 1.4%. Indeed, the resulting MF curves show signatures that suggest the uncommon behaviour to be associated with the presence of over- or under-densities there, but contamination due to residual foregrounds is not discarded. Additionally, even though our analyses indicate a good agreement among data and simulations, we identify 1 highly extreme region, seemingly associated to a large clustered distribution of galaxies. Our results confirm the usefulness of the MF to analyse GNC maps from photometric galaxy datasets.

  16. Developing a prenatal nursing care International Classification for Nursing Practice catalogue.

    Science.gov (United States)

    Liu, L; Coenen, A; Tao, H; Jansen, K R; Jiang, A L

    2017-09-01

    This study aimed to develop a prenatal nursing care catalogue of International Classification for Nursing Practice. As a programme of the International Council of Nurses, International Classification for Nursing Practice aims to support standardized electronic nursing documentation and facilitate collection of comparable nursing data across settings. This initiative enables the study of relationships among nursing diagnoses, nursing interventions and nursing outcomes for best practice, healthcare management decisions, and policy development. The catalogues are usually focused on target populations. Pregnant women are the nursing population addressed in this project. According to the guidelines for catalogue development, three research steps have been adopted: (a) identifying relevant nursing diagnoses, interventions and outcomes; (b) developing a conceptual framework for the catalogue; (c) expert's validation. This project established a prenatal nursing care catalogue with 228 terms in total, including 69 nursing diagnosis, 92 nursing interventions and 67 nursing outcomes, among them, 57 nursing terms were newly developed. All terms in the catalogue were organized by a framework with two main categories, i.e. Expected Changes of Pregnancy and Pregnancy at Risk. Each category had four domains, representing the physical, psychological, behavioral and environmental perspectives of nursing practice. This catalogue can ease the documentation workload among prenatal care nurses, and facilitate storage and retrieval of standardized data for many purposes, such as quality improvement, administration decision-support and researches. The documentations of prenatal care provided data that can be more fluently communicated, compared and evaluated across various healthcare providers and clinic settings. © 2016 International Council of Nurses.

  17. MANAJEMEN RANTAI PASOKAN JAGUNG ASALAN PADA CV AMIN DI LAMPUNG TENGAH

    Directory of Open Access Journals (Sweden)

    Rahmad Budiono

    2016-10-01

    Full Text Available Salah satu komoditi palawija yang memiliki peranan yang penting di Indonesia adalah jagung, karena merupakan sumber protein dan kalori yang sangat dibutuhkan oleh ayam peternak. Pengiriman yang belum tepat waktu merupakan penyebab belum efisiennya kinerja rantai pasokan jagung. Oleh karena itu penelitian ini bertujuan untuk (1 mengidentifikasi dan mengkaji pengelolaan rantai pasokan jagung pada CV. AMIN, (2 menganalisis kinerja rantai pasokan jagung dalam hal efisiensi dan pelaksanaan kemitraan, dan (3 menganalisis alternatif kebijakan pengembangan manajemen rantai pasokan berdasarkan hasil evaluasi rantai pasokan.Penelitian akan dilakukan di CV. AMIN, Jl. Raya Merapi, Lampung Tengah dan petani mitra yang berada di kabupaten Nganjuk. Penelitian mengenai manajemen rantai pasokan Jagung tersebut dilakukan pada bulan Desember 2012 hingga Januari 2013. Pengumpulan data dilakukan dengan observasi. Responden dalam penelitian ini adalah petani jagung yang berada di Nganjuk, Pengepul, pihak CV. AMIN, dan Gudang Ternak. Penelitian dilakukan dengan metode analisis deskriptif kerangka Food Supply Chain Networking (FSCN, analisis tataniaga, dan analisis deskriptif dengan menggunakan kesesuaian atribut.

  18. PAI-1 4G/5G gene polymorphism is associated with angiographic patency in ST-elevation myocardial infarction patients treated with thrombolytic therapy.

    Science.gov (United States)

    Ozkan, Bugra; Cagliyan, Caglar E; Elbasan, Zafer; Uysal, Onur K; Kalkan, Gulhan Y; Bozkurt, Mehmet; Tekin, Kamuran; Bozdogan, Sevcan T; Ozalp, Ozge; Duran, Mustafa; Sahin, Durmus Y; Cayli, Murat

    2012-09-01

    In this study, we examined the relationship between PAI-1 4G/5G polymorphism and patency of the infarct-related artery after thrombolysis in patients with ST-elevation myocardial infarction (STEMI). Acute STEMI patients who received thrombolytic therapy within first 12 h were included in our study. The PAI-1 4G/5G promoter region insertion/deletion polymorphism was studied from venous blood samples. Patients with the PAI-1 4G/5G gene polymorphism were included in group 1 and the others were included in group 2. Coronary angiography was performed in all patients in the first 24 h after receiving thrombolytic therapy. Thrombolysis in myocardial infarction (TIMI) 0-1 flow in the infarct-related artery was considered as 'no flow', TIMI 2 flow as 'slow flow', and TIMI 3 flow as 'normal flow'. A total of 61 patients were included in our study. Thirty patients (49.2%) were positive for the PAI-1 4G/5G gene polymorphism, whereas 31 of them (50.8%) were in the control group. There were significantly more patients with 'no flow' (14 vs. 6; P=0.02) and less patients with 'normal flow' (8 vs. 19; P=0.02) in group 1. In addition, time to thrombolytic therapy (TTT) was maximum in the 'no flow' group and minimum in the 'normal flow' group (P=0.005). In the logistic regression analysis, TTT (odds ratio: 0.9898; 95% confidence interval: 0.982-0.997; P=0.004) and the PAI-1 4G/5G gene polymorphism (odds ratio: 4.621; 95% confidence interval: 1.399-15.268; P5G gene polymorphism and TTT are associated independently with 'no flow' after thrombolysis in patients with STEMI.

  19. Effect of Sodium Cyanide on Wheat (Triticum durum cv. Altar and T. aestivum cv. Cumhuriyet)

    DEFF Research Database (Denmark)

    Gemici, Meliha; Karshenass, A.M.; Tan, Kit

    2008-01-01

    The effect of sodium cyanide on the morphology of stem, leaves and grain yields of Triticum durum cv. Altar and Triticum aestivum cv. Cumhuriyet grown under glass was studied. Seeds were planted in six different sets of pots containing ordinary garden soil. After formation of the first leaves......, the first set was used as the control and watered using ordinary bottled water sold commercially. The other five sets with T. durum cv. Altar and T. aestivum cv. Cumhuriyet seedlings were additionally watered with various concentrations of sodium cyanide, the test-quantity used being 10-50 mg/L. Growth...... of individual plants was monitored until grain production. It was found that the sodium cyanide concentrations in the feed solutions affected plant stature, with the plants becoming progressively dwarfed with increasing dosage. Anomalies in the morphological and anatomical structure of the plant were also noted...

  20. Global Compilation of InSAR Earthquake Source Models: Comparisons with Seismic Catalogues and the Effects of 3D Earth Structure

    Science.gov (United States)

    Weston, J. M.; Ferreira, A. M.; Funning, G. J.

    2010-12-01

    should map epicentral locations accurately, this allows us to obtain a first independent estimate of epicentral location errors in the seismic catalogues. InSAR depths are systematically shallower than those in the EHB catalogue with differences of 5-10km; we discuss the possible reasons for these differences, which allow us to place constraints on the accuracy of both ICMT and EHB depth determinations. Finally, we carry out long-period surface-wave CMT inversions using four different 3D global tomographic models and two different forward modelling techniques to assess the effect of inaccurate wave propagation formulations and/or 3D Earth structure on the source parameter comparisons. We find that comparing InSAR source models with the range of seismic solutions that we obtain is a useful way to assess limitations in the earthquake models, notably in identifying inaccuracies in the retrieved earthquake slip distribution using InSAR. Moreover, we find that using more accurate formulations, together with the best fitting Earth models, further reduces differences between the seismic moment determined using InSAR and seismic data.

  1. 4G/5G polymorphism modulates PAI-1 circulating levels in obese women.

    Science.gov (United States)

    Fernandes, Karla S; Sandrim, Valéria C

    2012-05-01

    The increase in plasminogen activator inhibitor type 1 (PAI-1) has been described as a risk factor to thrombosis-related diseases. In addition, it has been demonstrated that the variant 4G of polymorphism 4G/5G located in promoter region of PAI-1 gene is associated with higher PAI-1 levels. We investigate the role of this polymorphism on circulating PAI-1 concentration in a population of 57 obese women (23%, 4G/4G; 49%, 4G/5G and 28%, 5G/5G genotypes). Our results demonstrate a genotype-specific modulation on PAI-1 levels in obese women, thus 5G/5G genotype presented significantly lower levels of plasma PAI-1 when compared to 4G/4G group (46 ± 19 ng/mL vs. 63 ± 13 ng/mL, respectively). Our findings indicate that obese carriers of 4G/4G genotype may have increased risk to develop thrombotic diseases.

  2. Avaliação da cv. Tannat para elaboração de vinho tinto Evaluation of cv. Tannat to elaborate red wine

    Directory of Open Access Journals (Sweden)

    Luiz Antenor Rizzon

    2004-06-01

    Full Text Available A uva Tannat, originária do Sudoeste da França, foi introduzida no Rio Grande do Sul, pela Estação Experimental de Caxias do Sul. É uma cultivar difundida na Serra Gaúcha para elaboração de vinho tinto, utilizado para corte e para a produção de vinho varietal. O objetivo do presente trabalho foi avaliar o potencial enológico da cv. Tannat para a elaboração de vinho tinto fino nessa região vitícola. Para isso, realizaram-se estudos para caracterizar o cacho, o mosto e o vinho nas safras de 1987 a 1994, a partir de um vinhedo localizado em Bento Gonçalves, RS. Os resultados evidenciaram que a cv. Tannat tem cacho com peso médio de 216,1g e baga esférica pequena (1,54g. O mosto apresenta teor elevado de acidez titulável (155meq/L-1. O vinho se caracteriza por teores elevados em: polifenóis totais (I 280= 43,0, taninos (1,9g/L, antocianinas (539mg/L, potássio (1.856mg/L-1 e soma dos álcoois superiores (512mg/L-1. As características sensoriais do vinho Tannat na Serra Gaúcha evidenciam uma cor vermelha-violácea intensa, tânicos, nervosos, relativamente duros e aromas de frutas vermelhas. É recomendável para corte com outros vinhos tintos finos para intensificar sua cor e estrutura e também para a produção de vinho varietal podendo melhorar com o amadurecimento em barricas de carvalho.The Tannat grape is native to the Southwest of France, and was introduced into the State of Rio Grande do Sul by the Caxias do Sul Experimental Station. It is a cultivar diffused in the Serra Gaucha region with the purpose of elaborating varietal red wine for blending. The purpose of this work was to evaluate the enological potential of the Tannat grape for red wine in this region. To achieve this objective, variables related to the berries, clusters, must, and wine were evaluated from the 1987 to 1994 vintages, in a vineyard established in Bento Gonçalves, RS, Brazil. The results showed that Tannat grapes have large clusters (216.1g and

  3. High resolution spectral analysis of oxygen. IV. Energy levels, partition sums, band constants, RKR potentials, Franck-Condon factors involving the X3Σg−, a1Δg and b1Σg+ states

    International Nuclear Information System (INIS)

    Yu, Shanshan; Drouin, Brian J.; Miller, Charles E.

    2014-01-01

    We have updated the isotopically invariant Dunham fit of O 2 with newly reported literature transitions to derive (1) the energy levels, partition sums, band-by-band molecular constants, and RKR potentials for the X 3 Σ g − , a 1 Δ g , and b 1 Σ g + states of the six O 2 isotopologues: 16 O 16 O, 16 O 17 O, 16 O 18 O, 17 O 17 O, 17 O 18 O, and 18 O 18 O; (2) Franck-Condon factors for their a 1 Δ g −X 3 Σ g − , b 1 Σ g + −X 3 Σ g − , and a 1 Δ g −b 1 Σ g + band systems. This new spectroscopic parameterization characterizes all known transitions within and between the X 3 Σ g − , a 1 Δ g , and b 1 Σ g + states within experimental uncertainty and can be used for accurate predictions of as yet unmeasured transitions. All of these results are necessary to provide a consistent linelist of all transitions which will be reported in a followup paper

  4. The SOAR Gravitational Arc Survey – I. Survey overview and photometric catalogues

    Energy Technology Data Exchange (ETDEWEB)

    Furlanetto, Cristina; Santiago, Basílio X.; Makler, Martín; Cypriano, Eduardo S.; Caminha, Gabriel B.; Pereira, Maria E. S.; Neto, Angelo Fausti; Estrada, Juan; Lin, Huan; Hao, Jiangang; McKay, Timothy A.; da Costa, Luiz N.; Maia, Marcio A. G.

    2013-04-11

    We present the first results of the SOAR (Southern Astrophysical Research) Gravitational Arc Survey (SOGRAS). The survey imaged 47 clusters in two redshift intervals centered at $z=0.27$ and $z=0.55$, targeting the richest clusters in each interval. Images were obtained in the $g'$, $r'$ and $i'$ bands using the SOAR Optical Imager (SOI), with a median seeing of 0.83, 0.76 and 0.71 arcsec, respectively, in these filters. Most of the survey clusters are located within the Sloan Digital Sky Survey (SDSS) Stripe 82 region and all of them are in the SDSS footprint. Photometric calibration was therefore performed using SDSS stars located in our SOI fields. We reached for galaxies in all fields the detection limits of $g \\sim 23.5$, $r \\sim 23$ and $i \\sim 22.5$ for a signal-to-noise ratio (S/N) = 3. As a by-product of the image processing, we generated a source catalogue with 19760 entries, the vast majority of which are galaxies, where we list their positions, magnitudes and shape parameters. We compared our galaxy shape measurements to those of local galaxies and concluded that they were not strongly affected by seeing. From the catalogue data, we are able to identify a red sequence of galaxies in most clusters in the lower $z$ range. We found 16 gravitational arc candidates around 8 clusters in our sample. They tend to be bluer than the central galaxies in the lensing cluster. A preliminary analysis indicates that $\\sim 10%$ of the clusters have arcs around them, with a possible indication of a larger efficiency associated to the high-$z$ systems when compared to the low-$z$ ones. Deeper follow-up images with Gemini strengthen the case for the strong lensing nature of the candidates found in this survey.

  5. An astrophysical interpretation of the remarkable g-mode frequency groups of the rapidly rotating γ Dor star, KIC 5608334

    Science.gov (United States)

    Saio, Hideyuki; Bedding, Timothy R.; Kurtz, Donald W.; Murphy, Simon J.; Antoci, Victoria; Shibahashi, Hiromoto; Li, Gang; Takata, Masao

    2018-06-01

    The Fourier spectrum of the γ-Dor variable KIC 5608334 shows remarkable frequency groups at ˜3, ˜6, ˜9, and 11-12 d-1. We explain the four frequency groups as prograde sectoral g modes in a rapidly rotating star. Frequencies of intermediate-to-high radial order prograde sectoral g modes in a rapidly rotating star are proportional to |m| (i.e. ν ∝ |m|) in the corotating frame as well as in the inertial frame. This property is consistent with the frequency groups of KIC 5608334 as well as the period versus period-spacing relation present within each frequency group, if we assume a rotation frequency of 2.2 d-1, and that each frequency group consists of prograde sectoral g modes of |m| = 1, 2, 3, and 4, respectively. In addition, these modes naturally satisfy near-resonance conditions νi ≈ νj + νk with mi = mj + mk. We even find exact resonance frequency conditions (within the precise measurement uncertainties) in many cases, which correspond to combination frequencies.

  6. Book reviews - Catalogue of Meteorites, 5th ed., revised and enlarged, by Monica M. Grady. Cambridge University Press, 2000, 689 pp., US $150.00 (ISBN 0521-66303-2)

    Science.gov (United States)

    Ivanova, Marina A.

    2002-02-01

    The Catalogue of Meteorites has a long tradition and is one of the most important reference publications for meteorite researchers and cosmochemists. The first Guide to the Catalogue of Meteorites was published in 1881 by Lazarus Fletcher, Keeper of Minerals at the British Museum (Natural History), and contained a description of the nature of meteorites and a list of the 361 samples then in the museum's collection. Over the past century, this list was expanded to include more than just the meteorites that were in the possession of the British Museum; an attempt was made to include names, location, and other information on all meteorites known at the time. Thus, the first Catalogue of Meteorites was published in 1923 by G. T. Prior. His successor at the British Museum was Max H. Hey, who published appendixes to Prior's Catalogue, as well as the second and third editions of the Catalogue of Meteoritesin 1953 and 1966. An appendix to the third edition was published in 1977. Traditionally, the Catalogue contained a listing of all the specimens in any of the world's meteorite collections, in museums or otherwise. With the discovery of large numbers of meteorites in Antarctica, starting in 1969, the publishers of the Catalogue encountered some problems, as hundreds-even thousands-of specimens, many of which may be paired, were brought back from Antarctica from the 1970s onward. The fourth edition of the Catalogue, published in 1985 by Andrew Graham, Alex Bevan, and Robert Hutchison, was the first to deal with this sudden inflation of the number of meteorites. Because most of the thousands of Antarctic meteorites (except the obviously more unusual types, such as irons and certain achondrites) had not been studied in any detail, the fourth edition of the Catalogue wisely limited the entries of these meteorites (in some cases, only those with masses larger than 500 g were included in the Catalogue). The fourth edition of the Catalogue was a handsome and handy reference book

  7. The Arabidopsis homolog of human G3BP1 is a key regulator of stomatal and apoplastic immunity

    KAUST Repository

    Abulfaraj, Aala A.; Mariappan, Kiruthiga; Bigeard, Jean; Manickam, Prabhu; Blilou, Ikram; Guo, Xiujie; Al-Babili, Salim; Pflieger, Delphine; Hirt, Heribert; Rayapuram, Naganand

    2018-01-01

    Mammalian Ras-GTPase–activating protein SH3-domain–binding proteins (G3BPs) are a highly conserved family of RNA-binding proteins that link kinase receptor-mediated signaling to RNA metabolism. Mammalian G3BP1 is a multifunctional protein that functions in viral immunity. Here, we show that the Arabidopsis thaliana homolog of human G3BP1 negatively regulates plant immunity. Arabidopsis g3bp1 mutants showed enhanced resistance to the virulent bacterial pathogen Pseudomonas syringae pv. tomato. Pathogen resistance was mediated in Atg3bp1 mutants by altered stomatal and apoplastic immunity. Atg3bp1 mutants restricted pathogen entry into stomates showing insensitivity to bacterial coronatine–mediated stomatal reopening. AtG3BP1 was identified as a negative regulator of defense responses, which correlated with moderate up-regulation of salicylic acid biosynthesis and signaling without growth penalty.

  8. The Arabidopsis homolog of human G3BP1 is a key regulator of stomatal and apoplastic immunity

    KAUST Repository

    Abulfaraj, Aala Abdulaziz Hussien

    2018-05-31

    Mammalian Ras-GTPase–activating protein SH3-domain–binding proteins (G3BPs) are a highly conserved family of RNA-binding proteins that link kinase receptor-mediated signaling to RNA metabolism. Mammalian G3BP1 is a multifunctional protein that functions in viral immunity. Here, we show that the Arabidopsis thaliana homolog of human G3BP1 negatively regulates plant immunity. Arabidopsis g3bp1 mutants showed enhanced resistance to the virulent bacterial pathogen Pseudomonas syringae pv. tomato. Pathogen resistance was mediated in Atg3bp1 mutants by altered stomatal and apoplastic immunity. Atg3bp1 mutants restricted pathogen entry into stomates showing insensitivity to bacterial coronatine–mediated stomatal reopening. AtG3BP1 was identified as a negative regulator of defense responses, which correlated with moderate up-regulation of salicylic acid biosynthesis and signaling without growth penalty.

  9. Acceptance and Commitment Group Therapy (ACT-G) for health anxiety.

    Science.gov (United States)

    Eilenberg, Trine

    2016-10-01

    transfer benefits and also includes a matched general population register control cohort (n=12,600). In this thesis, we wish to answer the following questions: 1) Is ACT-G an acceptable, feasible and effective treatment approach for patients with severe health anxiety? 2) Can ACT-G improve severe illness worry compared with a waitlist control condition, and are the recently introduced diagnostic criteria for health anxiety acceptable for the patients? 3) Do patients with health anxiety show more sick leave than the general population during a 5-year period, and can ACT-G reduce sick leave measured by transfer benefits (weeks on sickness-related benefits) at 1-year follow-up? As ACT has not previously been examined as treatment approach for health anxiety, we initially conducted an uncontrolled pilot study to test the newly developed manualised program (ACT-G). The study included 34 patients with severe health anxiety and showed very low dropout and high treatment satisfaction. Significant improvements in self-reported illness worry were demonstrated post-treatment, and the results were sustained and further improved at 3- and 6-months follow-up compared to baseline. The subsequent RCT found high acceptance of the diagnosis of health anxiety. All patients (except 1) accepted the diagnosis as the right diagnosis to fit their ailment, and the majority of the patients found that the diagnosis helped them to better understand their symptoms. In an intention-to-treat analysis, ACT-G showed significant effect in the improvement of self-reported illness worry and other secondary measures compared with a waitlist control condition, both post-treatment and at 10-month follow-up (6 months post-treatment). The results were considered clinically significant as 2/3 of the patients in ACT-G at follow-up had demonstrated a pre-defined treatment response, and ¼ of the patients were considered to no longer have clinical case status. Furthermore, the number needed to treat was found to be 2

  10. On the uniform perfectness of equivariant diffeomorphism groups for principal G manifolds

    Directory of Open Access Journals (Sweden)

    Kazuhiko Fukui

    2017-01-01

    Full Text Available We proved in [K. Abe, K. Fukui, On commutators of equivariant diffeomorphisms, Proc. Japan Acad. 54 (1978, 52-54] that the identity component \\(\\text{Diff}\\,^r_{G,c}(M_0\\ of the group of equivariant \\(C^r\\-diffeomorphisms of a principal \\(G\\ bundle \\(M\\ over a manifold \\(B\\ is perfect for a compact connected Lie group \\(G\\ and \\(1 \\leq r \\leq \\infty\\ (\\(r \

  11. Post dural puncture headache after spinal anaesthesia for caesarean section: a comparison of 25G quince, 27G quince and 27G whitacre spinal needles

    International Nuclear Information System (INIS)

    Shaikh, J.M.; Memon, M.; Khan, M.

    2008-01-01

    To compare the frequency and severity of post dural puncture headache in obstetric patients using 25G Quincke, 27G Quincke and 27G Whitacre spinal needles. Comparative, randomized, double-blind, interventional study. 480 ASA I-II full term pregnant women, 18 to 45 years of age, scheduled for elective Caesarean section, under spinal anaesthesia, were randomized into three groups: Group I (25G Quincke spinal needle: n=168), Group II (27G Quincke spinal needle: n=160) and Group III (27G Whitacre spinal needle: n=152). Spinal anaesthesia was performed with 1.5-2.0 ml 0.75% hyperbaric bupivacaine using 25G Quincke spinal needle (Group I), 27G Quincke spinal needle (Group II) and 27G Whitacre spinal needle (Group III) at L3-4 inter-vertebral space. Each patient was assessed daily for four consecutive days following Caesarean section. Frequency and severity and of postdural puncture headache (PDPH) were recorded. Data were analyzed using SPSS-11. Frequency of PDPH following the use of 25G Quincke (Group I), 27G Quincke (Group II) and 27G Whitacre (Group III) spinal needles was 8.3% (14/168), 3.8% (6/160) and 2.0% (3/152) respectively. In Group I, PDPH was mild in 5 patients, moderate in 7 patients and severe in 2 patients. In Group II, it was mild in 2, moderate in 3 and severe in 1 patient. In group III, it was mild in 2 and moderate in 1 patient. Severe PDPH did not occur in Group III. Most of the patients with PDPH developed it on 1st and 2nd postoperative day. When using a 27G Whitacre spinal needle, the frequency and severity of PDPH was significantly lower than when a 25G Quincke or 27G Quincke needle was used. (author)

  12. Multiband Study of Radio Sources of the RCR Catalogue with Virtual Observatory Tools

    Directory of Open Access Journals (Sweden)

    Zhelenkova O. P.

    2012-09-01

    Full Text Available We present early results of our multiband study of the RATAN Cold Revised (RCR catalogue obtained from seven cycles of the “Cold” survey carried with the RATAN-600 radio telescope at 7.6 cm in 1980-1999, at the declination of the SS 433 source. We used the 2MASS and LAS UKIDSS infrared surveys, the DSS-II and SDSS DR7 optical surveys, as well as the USNO-B1 and GSC-II catalogues, the VLSS, TXS, NVSS, FIRST and GB6 radio surveys to accumulate information about the sources. For radio sources that have no detectable optical candidate in optical or infrared catalogues, we additionally looked through images in several bands from the SDSS, LAS UKIDSS, DPOSS, 2MASS surveys and also used co-added frames in different bands. We reliably identified 76% of radio sources of the RCR catalogue. We used the ALADIN and SAOImage DS9 scripting capabilities, interoperability services of ALADIN and TOPCAT, and also other Virtual Observatory (VO tools and resources, such as CASJobs, NED, Vizier, and WSA, for effective data access, visualization and analysis. Without VO tools it would have been problematic to perform our study.

  13. Chronology of formation of early solar system solids from bulk Mg isotope analyses of CV3 chondrules

    Science.gov (United States)

    Chen, Hsin-Wei; Claydon, Jennifer L.; Elliott, Tim; Coath, Christopher D.; Lai, Yi-Jen; Russell, Sara S.

    2018-04-01

    We have analysed the petrography, major element abundances and bulk Al-Mg isotope systematics of 19 ferromagnesian chondrules from the CV3 chondrites Allende, Mokoia, and Vigarano, together with an Al-rich chondrule and refractory olivine from Mokoia. Co-variations of Al/Mg with Na/Mg and Ti/Mg in our bulk chondrules suggest their compositions are dominantly controlled by reworking of different proportions of chondrule components (e.g. mafic minerals and mesostatis); their precursors are thus fragments from prior generations of chondrules. Our samples show a range in fractionation corrected 26Mg/24Mg (Δ‧26Mg) ∼ 60 ppm, relative to precisions behaviour once 26Al was effectively extinct ((26Al/27Al)0 3.4 ± 0.6 × 10-5. Overall, our samples record a sequence of events from the formation of ferromagnesian objects within 0.5 Ma of CAI to re-equilibration of chondrules and silicate vapour >2 Ma post CAI, assuming an initially homogeneous 26Al/27Al. Metamorphism on the asteroid parent body may have played a subsequent role in affecting Mg isotope composition, but we argue this had a minor influence on the observations here.

  14. Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3'-diindolylmethane in HT-29 human colon cancer cells

    Directory of Open Access Journals (Sweden)

    Choi Hyun

    2009-05-01

    Full Text Available Abstract Background 3,3'-Diindolylmethane (DIM, an indole derivative produced in the stomach after the consumption of broccoli and other cruciferous vegetables, has been demonstrated to exert anti-cancer effects in both in vivo and in vitro models. We have previously determined that DIM (0 – 30 μmol/L inhibited the growth of HT-29 human colon cancer cells in a concentration-dependent fashion. In this study, we evaluated the effects of DIM on cell cycle progression in HT-29 cells. Methods HT-29 cells were cultured with various concentrations of DIM (0 – 30 μmol/L and the DNA was stained with propidium iodide, followed by flow cytometric analysis. [3H]Thymidine incorporation assays, Western blot analyses, immunoprecipitation and in vitro kinase assays for cyclin-dependent kinase (CDK and cell division cycle (CDC2 were conducted. Results The percentages of cells in the G1 and G2/M phases were dose-dependently increased and the percentages of cells in S phase were reduced within 12 h in DIM-treated cells. DIM also reduced DNA synthesis in a dose-dependent fashion. DIM markedly reduced CDK2 activity and the levels of phosphorylated retinoblastoma proteins (Rb and E2F-1, and also increased the levels of hypophosphorylated Rb. DIM reduced the protein levels of cyclin A, D1, and CDK4. DIM also increased the protein levels of CDK inhibitors, p21CIP1/WAF1 and p27KIPI. In addition, DIM reduced the activity of CDC2 and the levels of CDC25C phosphatase and cyclin B1. Conclusion Here, we have demonstrated that DIM induces G1 and G2/M phase cell cycle arrest in HT-29 cells, and this effect may be mediated by reduced CDK activity.

  15. Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3'-diindolylmethane in HT-29 human colon cancer cells.

    Science.gov (United States)

    Choi, Hyun Ju; Lim, Do Young; Park, Jung Han Yoon

    2009-05-29

    3,3'-Diindolylmethane (DIM), an indole derivative produced in the stomach after the consumption of broccoli and other cruciferous vegetables, has been demonstrated to exert anti-cancer effects in both in vivo and in vitro models. We have previously determined that DIM (0 - 30 micromol/L) inhibited the growth of HT-29 human colon cancer cells in a concentration-dependent fashion. In this study, we evaluated the effects of DIM on cell cycle progression in HT-29 cells. HT-29 cells were cultured with various concentrations of DIM (0 - 30 micromol/L) and the DNA was stained with propidium iodide, followed by flow cytometric analysis. [3H]Thymidine incorporation assays, Western blot analyses, immunoprecipitation and in vitro kinase assays for cyclin-dependent kinase (CDK) and cell division cycle (CDC)2 were conducted. The percentages of cells in the G1 and G2/M phases were dose-dependently increased and the percentages of cells in S phase were reduced within 12 h in DIM-treated cells. DIM also reduced DNA synthesis in a dose-dependent fashion. DIM markedly reduced CDK2 activity and the levels of phosphorylated retinoblastoma proteins (Rb) and E2F-1, and also increased the levels of hypophosphorylated Rb. DIM reduced the protein levels of cyclin A, D1, and CDK4. DIM also increased the protein levels of CDK inhibitors, p21CIP1/WAF1 and p27KIPI. In addition, DIM reduced the activity of CDC2 and the levels of CDC25C phosphatase and cyclin B1. Here, we have demonstrated that DIM induces G1 and G2/M phase cell cycle arrest in HT-29 cells, and this effect may be mediated by reduced CDK activity.

  16. Catalogue of ptyctimous mites (Acari, Oribatida) of the world.

    Science.gov (United States)

    NiedbaŁa, Wojciech; Liu, Dong

    2018-03-11

    As important representatives of Oribatida (Acari), ptyctimous mites comprise more than 1400 described species in 40 genera and subgenera, with nearly cosmopolitan distribution except for the Arctic and Antarctic Regions. They are capable of folding the aspidosoma under the opisthosoma to protect their appendages, and are primarily soil and litter inhabitants, feeding on fungi and decaying plant remains with various levels of specificity. Our purpose was to provide a detailed catalogue of all known ptyctimous mite species in the world with information of distribution, taxonomic issues and some remarks. Data of known juvenile  instars of ptyctimous mites which were not included in Norton Ermilov (2014) were added. We hope that our catalogue with bibliography will be helpful in taxonomic and ecological studies.        The catalogue presents taxonomic information and geographic distribution of 1431 known species of the world belonging to 42 genera and eight families (not including data of genus and species inquirenda, nomina nuda and species without author name). Among them, 261 species are listed as synonyms, 43 species inquirenda, nine homonyms, 17 new synonyms, one new subgenus Mahuntritia subgenus nov. and three new names are included in the catalogue.

  17. Version 2000 of the Catalogue of Galactic Planetary Nebulae

    Science.gov (United States)

    Kohoutek, L.

    2001-11-01

    The ``Catalogue of Galactic Planetary Nebulae (Version 2000)'' appears in Abhandlungen aus der Hamburger Sternwarte, Band XII in the year 2001. It is a continuation of CGPN(1967) and contains 1510 objects classified as galactic PNe up to the end of 1999. The lists of possible pre-PNe and possible post-PNe are also given. The catalogue is restricted only to the data belonging to the location and identification of the objects. It gives identification charts of PNe discovered since 1965 (published in the supplements to CGPN) and those charts of objects discovered earlier, which have wrong or uncertain identification. The question ``what is a planetary nebula'' is discussed and the typical values of PNe and of their central stars are summarized. Short statistics about the discoveries of PNe are given. The catalogue is also available in the Centre de Données, Strasbourg and at Hamburg Observatory via internet. The Catalogue is only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/cgi-bin/qcat?J/A+A/378/843

  18. Tetrahydro-2,1,3-boraoxazines - a new group boron heterocyclics

    International Nuclear Information System (INIS)

    Piotrowska, H.; Serafin, B.; Urbanski, T.; Vasudeva, S.K.

    1977-01-01

    The synthesis of new group of compounds derivative of tetrahydro-2,1,3 boraoxazine(5) by condensation of aminoalcohols 3 with aryloboronic acids(4) was carried out. The properties of new compounds are presented. (B.C.)

  19. INTERACT Station Catalogue - 2015

    DEFF Research Database (Denmark)

    INTERACT stations are located in all major environmental envelopes of the Arctic providing an ideal platform for studying climate change and its impact on the environment and local communities. Since alpine environments face similar changes and challenges as the Arctic, the INTERACT network also ...... catalogue includes descriptions of 73 research stations included in the network at the time of printing....

  20. Inhibition of Rac1 activity induces G1/S phase arrest through the GSK3/cyclin D1 pathway in human cancer cells.

    Science.gov (United States)

    Liu, Linna; Zhang, Hongmei; Shi, Lei; Zhang, Wenjuan; Yuan, Juanli; Chen, Xiang; Liu, Juanjuan; Zhang, Yan; Wang, Zhipeng

    2014-10-01

    Rac1 has been shown to regulate the cell cycle in cancer cells. Yet, the related mechanism remains unclear. Thus, the present study aimed to investigate the mechanism involved in the regulation of G1/S phase transition by Rac1 in cancer cells. Inhibition of Rac1 by inhibitor NSC23766 induced G1/S phase arrest and inhibited the proliferation of A431, SW480 and U2-OS cells. Suppression of GSK3 by shRNA partially rescued G1/S phase arrest and inhibition of proliferation. Incubation of cells with NSC23766 reduced p-AKT and inactivated p-GSK3α and p-GSK3β, increased p-cyclin D1 expression and decreased the level of cyclin D1 protein. Consequently, cyclin D1 targeting transcriptional factor E2F1 expression, which promotes G1 to S phase transition, was also reduced. In contrast, constitutive active Rac1 resulted in increased p-AKT and inactivated p-GSK3α and p-GSK3β, decreased p-cyclin D1 expression and enhanced levels of cyclin D1 and E2F1 expression. Moreover, suppression of GSK3 did not alter p-AKT or Rac1 activity, but decreased p-cyclin D1 and increased total cyclin D1 protein. However, neither Rac1 nor GSK3 inhibition altered cyclin D1 at the RNA level. Moreover, after inhibition of Rac1 or GSK3 following proteasome inhibitor MG132 treatment, cyclin D1 expression at the protein level remained constant, indicating that Rac1 and GSK3 may regulate cyclin D1 turnover through phosphorylation and degradation. Therefore, our findings suggest that inhibition of Rac1 induces cell cycle G1/S arrest in cancer cells by regulation of the GSK3/cyclin D1 pathway.

  1. Planck 2013 results. XXIX. Planck catalogue of Sunyaev-Zeldovich sources

    DEFF Research Database (Denmark)

    Ade, P. A. R.; Aghanim, N.; Armitage-Caplan, C.

    2013-01-01

    We describe the all-sky Planck catalogue of clusters and cluster candidates derived from Sunyaev-Zeldovich (SZ) effect detections using the first 15.5 months of Planck satellite observations. The catalogue contains 1227 entries, making it over six times the size of the Planck Early SZ (ESZ) sampl...

  2. Pengaruh sistem vulkanisasi konvensional (CV dan semi efisien (SEV terhadap sifat aging dan termal vulkanisat campuran karet alam dan karet butil

    Directory of Open Access Journals (Sweden)

    Arum Yuniari

    2015-12-01

    Full Text Available The purpose of this research was to study the effect of CV and SEV curing systems on aging and thermal properties of natural rubber and butyl rubber blends. The mixing of rubber and rubber chemicals using two roll-mills and the vulcanization process was carried out by the hydraulic press at 160° C and 150 kg/cm2. The research design used two variations; first, the CV curing system (accelerator/sulfur (1.0/2.5 phr and SEV curing system (accelerator/sulfur (2.1/1.5 phr, second, the ratio of natural rubber/butyl: 100/0; 95/5; 90/10; 85/15; 80/20; 75/25; 70/30; 65/35; 60/40 and 55/45 phr. The parameter observed were tensile strength, elongation at break, hardness before and after aging and thermal properties, e.g.TG/DTA and DSC. The results showed that CV curing systems provided tensile, elongation at break properties gave higher quality and better aging properties. TG/DTA analysis of vulcanizates processed with CV curing systems provided slightly better thermal stability than of the SEV curing system.

  3. Evaluation of a competitive enzyme-linked immunosorbent assay for measurements of soluble HLA-G protein

    DEFF Research Database (Denmark)

    Rasmussen, M; Dahl, M; Buus, S

    2014-01-01

    . We report a novel method, a competitive immunoassay, for measuring HLA-G5/sHLA-G1 in biological fluids. The sHLA-G immunoassay is based upon a competitive enzyme-linked immunosorbent assay (ELISA) principle. It includes a recombinant sHLA-G1 protein in complex with β2-microglobulin and a peptide...... as a standard, biotinylated recombinant sHLA-G1 as an indicator, and the MEM-G/9 anti-HLA-G monoclonal antibody (mAb) as the capture antibody. The specificity and sensitivity of the assay were evaluated. Testing with different recombinant HLA class I proteins and different anti-HLA class I mAbs showed....../ml. An intra-assay coefficient of variation (CV) of 15.5% at 88 ng/ml and an inter-assay CV of 23.1% at 39 ng/ml were determined. An assay based on the competitive sHLA-G ELISA may be important for measurements of sHLA-G proteins in several conditions: assisted reproduction, organ transplantation, cancer...

  4. Plasminogen activator inhibitor-1 4G/5G gene polymorphism and coronary artery disease in the Chinese Han population: a meta-analysis.

    Directory of Open Access Journals (Sweden)

    Yan-yan Li

    Full Text Available BACKGROUND: The polymorphism of plasminogen activator inhibitor-1 (PAI-1 4G/5G gene has been indicated to be correlated with coronary artery disease (CAD susceptibility, but study results are still debatable. OBJECTIVE AND METHODS: The present meta-analysis was performed to investigate the association between PAI-1 4G/5G gene polymorphism and CAD in the Chinese Han population. A total of 879 CAD patients and 628 controls from eight separate studies were involved. The pooled odds ratio (OR for the distribution of the 4G allele frequency of PAI-1 4G/5G gene and its corresponding 95% confidence interval (CI was assessed by the random effect model. RESULTS: The distribution of the 4 G allele frequency was 0.61 for the CAD group and 0.51 for the control group. The association between PAI-1 4G/5G gene polymorphism and CAD in the Chinese Han population was significant under an allelic genetic model (OR = 1.70, 95% CI = 1.18 to 2.44, P = 0.004. The heterogeneity test was also significant (P<0.0001. Meta-regression was performed to explore the heterogeneity source. Among the confounding factors, the heterogeneity could be explained by the publication year (P = 0.017, study region (P = 0.014, control group sample size (P = 0.011, total sample size (P = 0.011, and ratio of the case to the control group sample size (RR (P = 0.019. In a stratified analysis by the total sample size, significantly increased risk was only detected in subgroup 2 under an allelic genetic model (OR = 1.93, 95% CI = 1.09 to 3.35, P = 0.02. CONCLUSIONS: In the Chinese Han population, PAI-1 4G/5G gene polymorphism was implied to be associated with increased CAD risk. Carriers of the 4G allele of the PAI-1 4G/5G gene might predispose to CAD.

  5. The effect of subminimal inhibitory concentrations of penicillin on growth rate and haemolysin activity of group G Streptococcus

    Directory of Open Access Journals (Sweden)

    Verônica V. Vieira

    1993-09-01

    Full Text Available The influence of the subminimal inhibitory concentrations (1/3 and 1/4 of the MIC of penicillin on growth rate and on haemolysin production of a strain of group G Streptococcus was studied. It was shown that 1/3 of the MIC almost completely inhibited the bacterial growth, but it was not able to inhibit haemolysin activity in the culture supernate. The generation time of bacteria grown in 1/4 of the MIC was approximately twice longer than that of the control culture. In all cultures, the haemolysin, after being produced (or liberated, reached a peak and decreased to low levels, which could suggest that group G Streptococcus produces some end products of metabolism that are able to inhibit haemolysin activity.

  6. Facile synthesis of Fe3O4/g-C3N4/HKUST-1 composites as a novel biosensor platform for ochratoxin A.

    Science.gov (United States)

    Hu, Shuisheng; Ouyang, Wenjun; Guo, Longhua; Lin, Zhenyu; Jiang, Xiaohua; Qiu, Bin; Chen, Guonan

    2017-06-15

    A fluorescent biosensor for ochratoxin A was fabricated on the basis of a new nanocomposite (Fe 3 O 4 /g-C 3 N 4 /HKUST-1 composites). Fe 3 O 4 /g-C 3 N 4 /HKUST-1 was synthesized in this work for the first time, which combined HKUST-1 with g-C 3 N 4 to improve its chemical stability. Fe 3 O 4 /g-C 3 N 4 /HKUST-1 composites have strong adsorption capacity for dye-labeled aptamer and are able to completely quench the fluorescence of the dye through the photoinduced electron transfer (PET) mechanism. In the presence of ochratoxin A (OTA), it can bind with the aptamer with high affinity, causing the releasing of the dye-labeled aptamer from the Fe 3 O 4 /g-C 3 N 4 /HKUST-1 and therefore results in the recovery of fluorescence. The fluorescence intensity of the biosensor has a linear relationship with the OTA concentration in the range of 5.0-160.0ng/mL. The LOD of sensor is 2.57ng/mL (S/N=3). This fluorescence sensor based on the Fe 3 O 4 /g-C 3 N 4 /HKUST-1 composites has been applied to detect OTA in corn with satisfying results. Copyright © 2016. Published by Elsevier B.V.

  7. Geranyl acetate esterase controls and regulates the level of geraniol in lemongrass (Cymbopogon flexuosus Nees ex Steud.) mutant cv. GRL-1 leaves.

    Science.gov (United States)

    Ganjewala, Deepak; Luthra, Rajesh

    2009-01-01

    Essential oil isolated from lemongrass (Cymbopogon flexuosus) mutant cv. GRL-1 leaves is mainly composed of geraniol (G) and geranyl acetate (GA). The proportion of G and GA markedly fluctuates during leaf development. The proportions of GA and G in the essential oil recorded at day 10 after leaf emergence were approximately 59% and approximately 33% respectively. However, the level of GA went down from approximately 59 to approximately 3% whereas the level of G rose from approximately 33 to approximately 91% during the leaf growth period from day 10 to day 50. However, the decline in the level of GA was most pronounced in the early (day 10 to day 30) stage of leaf growth. The trend of changes in the proportion of GA and G has clearly indicated the role of an esterase that must be involved in the conversion of GA to G during leaf development. We isolated an esterase from leaves of different ages that converts GA into G and has been given the name geranyl acetate esterase (GAE). The GAE activity markedly varied during the leaf development cycle; it was closely correlated with the monoterpene (GA and G) composition throughout leaf development. GAE appeared as several isoenzymes but only three (GAE-I, GAE-II, and GAE-III) of them had significant GA cleaving activity. The GAE isoenzymes pattern was greatly influenced by the leaf developmental stages and so their GA cleaving activities. Like the GAE activity, GAE isoenzyme patterns were also found to be consistent with the monoterpene (GA and G) composition. GAE had an optimum pH at 8.5 and temperature at 30 degrees C. Besides GAE, a compound with phosphatase activity capable of hydrolyzing geranyl diphosphate (GPP) to produce geraniol has also been isolated.

  8. Analysis of ({sup 7}F{sub 0}){gamma}{sub 1g}{yields}({sup 5}D{sub 2}){gamma}{sub 5g}, {gamma}{sub 3g} and ({sup 7}F{sub 0}){gamma}{sub 1g}{yields}({sup 5}L{sub 6}){gamma}{sub 1g}, a{gamma}{sub 5g} two-photon absorption spectra of Cs{sub 2}NaYF{sub 6}:Eu{sup 3+}

    Energy Technology Data Exchange (ETDEWEB)

    Ning Lixin; Wang Dianyuan; Xia Shangda [Structure Research Laboratory, Academica Sinica, Department of Physics, University of Science and Technology of China, Heifei, Anhui (China); Thorne, Jonathan R.G. [Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford (United Kingdom); Tanner, Peter A. [Department of Biology and Chemistry, City University of Hong Kong, Kowloon (China)

    2002-04-15

    The direct calculation of transition line strengths and relative intensities is presented for two intraconfigurational two-photon absorption (TPA) transitions of Eu{sup 3+} in the cubic Cs{sub 2}NaYF{sub 6} host. Crystal field wavefunctions were utilized for the initial and final f{sup N}-electron states and various approaches were used in constructing all the 4f{sup N-1} 5d{sup 1} intermediate-state wavefunctions. The calculated relative intensities of the ({sup 7}F{sub 0}) {gamma}{sub 1g}{yields}({sup 5}D{sub 2}){gamma}{sub 5g}, {gamma}{sub 3g} TPA transitions are in reasonable agreement with experiment. The neglect of J-mixing in the initial state has only a small effect upon the calculation, whereas the neglect of spin-orbit couplings within the initial and terminal states drastically reduces the calculated transition linestrengths, but does not markedly change the intensity ratios. In the case of the ({sup 7}F{sub 0}){gamma}{sub 1g}{yields}({sup 5}L{sub 6}){gamma}{sub 1g}, a{gamma}{sub 5g} transitions, serious discrepancies between experiment and theory are found if the intermediate states are constructed from a 4f{sup 5} core comprising free ion states and the 5d{sup 1} crystal field states. Satisfactory agreement is, however, found when the 4f{sup 5} crystal field states are utilized in constructing the intermediate states. The contributions to the transition moment have been evaluated for various Hamiltonian terms and the results are discussed. (author)

  9. Where do we go with Union Catalogues?

    Directory of Open Access Journals (Sweden)

    Edmund Chamberlain

    2013-07-01

    Full Text Available The United Kingdom boasts union catalogues for its major research libraries, journal holdings, archives and, most recently, for its public library collections. For researchers wanting to locate material across the UK, such aggregations have long served as a first stop for researchers wanting to find the right material and also provided a showcase for our formidable research collections. In the global networked environment, search engines and social networks can fulfil much of the functionality of union catalogues and have become the natural places to which our users go for search and discovery, even in academic situations. Right now, there is a ‘disconnect’ between the data describing our collections and the places users first turn to start their searches. This can be fixed by exposing descriptive data to wider audiences beyond the silo of the local catalogue, but data publishing is a fast moving area with little obvious short-term institutional-level gain and some start-up barriers. Publishing library data to the open web at the level of a national aggregation would utilize existing skill sets and infrastructure, minimize risk and maximize impact.

  10. A multimembership catalogue for 1876 open clusters using UCAC4 data

    Science.gov (United States)

    Sampedro, L.; Dias, W. S.; Alfaro, E. J.; Monteiro, H.; Molino, A.

    2017-10-01

    The main objective of this work is to determine the cluster members of 1876 open clusters, using positions and proper motions of the astrometric fourth United States Naval Observatory (USNO) CCD Astrograph Catalog (UCAC4). For this purpose, we apply three different methods, all based on a Bayesian approach, but with different formulations: a purely parametric method, another completely non-parametric algorithm and a third, recently developed by Sampedro & Alfaro, using both formulations at different steps of the whole process. The first and second statistical moments of the members' phase-space subspace, obtained after applying the three methods, are compared for every cluster. Although, on average, the three methods yield similar results, there are also specific differences between them, as well as for some particular clusters. The comparison with other published catalogues shows good agreement. We have also estimated, for the first time, the mean proper motion for a sample of 18 clusters. The results are organized in a single catalogue formed by two main files, one with the most relevant information for each cluster, partially including that in UCAC4, and the other showing the individual membership probabilities for each star in the cluster area. The final catalogue, with an interface design that enables an easy interaction with the user, is available in electronic format at the Stellar Systems Group (SSG-IAA) web site (http://ssg.iaa.es/en/content/sampedro-cluster-catalog).

  11. HR diagrams derived from the Michigan Spectral Catalogue

    International Nuclear Information System (INIS)

    Houk, N.; Fesen, R.

    1978-01-01

    The authors present some HR diagrams constructed using data from the Michigan Spectral Catalogues. Houk (1975) has been systematically reclassifying the Henry Draper stars on the MK system, from the south pole northward. Objective-prism plates, with a reciprocal dispersion of 108 A/mm, have been taken with the Michigan Curtis Schmidt telescope at Cerro Tololo Inter-American Observatory in Chile. The spectra are classified visually from the plates, and the results are put onto IBM cards and magnetic tape from which the catalogues are produced. (Auth.)

  12. Effect of inoculation and nitrogen top-dressing on yields and fodder value of winter pea cv. Maksimirski ozimi in wheat cv. Sana mixture

    Directory of Open Access Journals (Sweden)

    Darko Uher

    2007-06-01

    Full Text Available Two year field trials (1999 - 2001 were performed to determine theinoculation seed winter pea and nitrogen top-dressing effect on number and active nodules of pea root and also on the green mass and dry matter yield of winter pea cv. Maksimirski ozimi and wheat cv. Sana mixture. Immediately before sowing the inoculation of pea seeds was accomplished by the indigenous variety of Rhizobium leguminosarum bv. viciae which belongs to the collection of Department of Microbiology at the Faculty of Agriculture University of Zagreb. The highest total nodule number on pea root (159 was determined on the inoculated variant as well as active nodule 144. Average mixture green mass yield were ranging from 24,65 t ha-1 (control up to 35,50 t ha-1 (inoculation. Total dry matter yields were ranging from 3,93 t ha-1 (control up to 5,66 t ha-1 (inoculation. Yields crude proteins pea in 2001 were ranging from 692 kg ha-1 (control up to 1058 kg ha-1 (inoculation and for wheat, those values ranged from 199 kg ha-1 (control up to 454 kg ha-1 (nitrogen top-dressing. Total crude proteins mixture yields were in range from 891 kg ha-1 (control up to 1360 kg ha-1 (inoculation.

  13. Points of View: Herbert Bayer’s Exhibition Catalogue for the 1930 Section Allemande

    Directory of Open Access Journals (Sweden)

    Wallis Miller

    2017-01-01

    Full Text Available Sigfried Giedion called Herbert Bayer’s exhibition catalogue for the 1930 'Section Allemande' a “minor typographical masterpiece.” Like similar catalogues, it is inexpensive, provides an inventory list, has an introduction, functions as a guide, and is illustrated. However, the majority of its images are of installations, not their contents. Bayer accommodates the catalogue type for applied arts exhibitions by listing installations as objects, but he confronts the type by showing installations as display contexts that establish points of view, emulating, idealizing and interpreting the experience of the exhibition. By independently constructing ways of seeing and understanding the exhibition, the catalogue resists being an appendage to the exhibition, despite their close relationship. Giedion may have viewed Bayer’s catalogue as an important but secondary work of graphic design, but this article argues that it is of primary significance as an exhibition catalogue, an unusual essay on the book typology that is conscious of its history while moving outside — to other types of book design and to exhibitions — to transform it.

  14. Selling pictures: the illustrated auction catalogue

    Directory of Open Access Journals (Sweden)

    Elizabeth Pergam

    2014-12-01

    Full Text Available This essay is based upon a survey of reproductions in auction catalogues – from their first appearance in the early eighteenth century until their more consistent use in the second decade of the twentieth century. Examining the role of these illustrations sheds light on how auctions functioned; it was not just the works of art that were traded, but knowledge about those works of art became currency to be exchanged. In contrast to the high end engravings and photographs of luxury illustrated art books, reproductions in auction catalogues – publications produced as ephemeral marketing tools – were of noticeably lower quality. This study of the status of reproductions, therefore, investigates the evolving understanding of art knowledge, both aesthetic and economic, and the interdependence of the market and connoisseurship.

  15. Catalogue of response spectra for unfolding in situ gamma-ray pulse-height distributions

    International Nuclear Information System (INIS)

    Dymke, N.

    1982-01-01

    To unfold in situ gamma-ray pulse-height distributions by means of a response matrix technique, the matrix must be in keeping with the measurement geometry, detector size, and energy range to be covered by the measurements. A methodology has been described for determination of standard gamma-ray spectra needed in deriving response matrices and a spectrum catalogue compiled containing graphs and data for the 0-3 MeV (4 x 4 in. NaI(Tl)) and 0-8 MeV (1.5 x 1.5 in. NaI(Tl)) ranges. (author)

  16. [Knockdown of STAT3 inhibits proliferation and migration of HepG2 hepatoma cells induced by IFN1].

    Science.gov (United States)

    Li, Xiaofang; Wang, Yuqi; Yan, Ben; Fang, Peipei; Ma, Chao; Xu, Ning; Fu, Xiaoyan; Liang, Shujuan

    2018-02-01

    Objective To prepare lentiviruses expressing shRNA sequences targeting human signal transducer and activator of transcription 3 (STAT3) and detect the effect of STAT3 knockdown on type I interferon (IFN1)-induced proliferation and migration in HepG2 cells. Methods Four STAT3-targeting shRNA sequences (shRNA1-shRNA4) and one control sequence (Ctrl shRNA) were selected and cloned respectively into pLKO.1-sp6-pgk-GFP to construct shRNA-expressing vectors. Along with backbone psPAX2 and pMD2.G vectors, they were separately transfected into HEK293T cells to prepare lentiviruses. HepG2 cells were infected with the lentiviruses. Cytoplastic STAT3 level was detected by Western blotting to screen effective shRNA sequence(s) targeting STAT3. Proliferation and migration of HepG2 cells were analyzed by CCK-8 assay and Transwell TM migration and scratching assay, respectively. To detect the effect of IFN1 on cell proliferation and migration of HepG2 cells, the cells were treated with 2000 U/mL IFNα2b for indicated time and the activation of IFN-triggered STAT1 signal transduction was assayed by Western blotting. Results Two most effective STAT3-targeting shRNA sequences shRNA1 and shRNA2 were selected, and the expression of both STAT3 shRNA significantly decreased proliferation and migration of HepG2 cells. When treated with IFNα2b, 2000 U/mL of IFN1 showed more competent in attenuating growth and migration of HepG2 cells. Our data further proved that knockdown of STAT3 increased the phosphorylation of STAT1, and IFNα2b further enhanced the activation of STAT1 signaling in HepG2 cells. Conclusion Knockdown of STAT3 inhibits cell migration and growth, and rescues IFN response through up-regulating STAT1 signal transduction in HepG2 hepatoma cells.

  17. Thermochemistry of 1,1,3,3-tetramethylguanidine and 1,1,3,3-tetramethylguanidinium nitrate

    International Nuclear Information System (INIS)

    Vitorino, Joana; Agapito, Filipe; Piedade, M. Fátima M.; Bernardes, Carlos E.S.; Diogo, Hermínio P.; Leal, João P.

    2014-01-01

    Graphical abstract: - Highlights: • The enthalpy of formation of 1,1,3,3-tetramethylguanidinium nitrate was determined by combustion calorimetry. • The cohesive energy of liquid 1,1,3,3-tetramethylguanidinium nitrate was evaluated. • The crystal structure of 1,1,3,3-tetramethylguanidinium nitrate was determined by single crystal X-ray diffraction. • Δ f H m o (l/g) of 1,1,3,3-tetramethylguanidine (tmg) were obtained by solution and Calvet calorimetry. • Δ f H m o (g) calculated by the W1-F12 procedure was in excellent agreement with the corresponding experimental value. - Abstract: Considerable efforts have recently been made to investigate how the structure of protic ionic liquids determines some of their most important properties for technological applications (e.g. low vapour pressure, conductivity). In contrast, the assessment of cohesive energies (which are also linked to those properties) based on thermodynamic results is still practically unexplored. This problem is addressed here for 1,1,3,3-tetramethylguanidinium nitrate, [Htmg][NO 3 ], through a combination of experimental and computational chemistry results at the reference temperature of 298.15 K. The standard molar enthalpies of formation, Δ f H m o ([Htmg][NO 3 ],cr)=-(311.8±2.3)kJ·mol -1 , and fusion, Δ fus H m o ([Htmg][NO 3 ])=16.2±3.8kJ·mol -1 , of solid 1,1,3,3-tetramethylguanidinium nitrate (form I polymorph) were obtained by combustion and differential scanning calorimetry, respectively. From these results Δ f H m o ([Htmg][NO 3 ],l)=-(295.6±4.4)kJ·mol -1 could be derived. Also determined were the standard molar enthalpies of formation, Δ f H m o (tmg, l)=7.7±2.8kJ·mol -1 , and vaporisation, Δ vap H m o (tmg,l)=50.0±1.2kJ·mol -1 , of 1,1,3,3-tetramethylguanidine, by reaction solution and Calvet-drop microcalorimetry, respectively, leading to Δ f H m o (tmg,g)=57.7±3.0kJ·mol -1 . This result is in excellent agreement with Δ f H m o (tmg,g)=58.4±4.0kJ·mol -1

  18. MAPLE Fabricated Fe3O4@Cinnamomum verum Antimicrobial Surfaces for Improved Gastrostomy Tubes

    Directory of Open Access Journals (Sweden)

    Alina Georgiana Anghel

    2014-06-01

    Full Text Available Cinnamomum verum-functionalized Fe3O4 nanoparticles of 9.4 nm in size were laser transferred by matrix assisted pulsed laser evaporation (MAPLE technique onto gastrostomy tubes (G-tubes for antibacterial activity evaluation toward Gram positive and Gram negative microbial colonization. X-ray diffraction analysis of the nanoparticle powder showed a polycrystalline magnetite structure, whereas infrared mapping confirmed the integrity of C. verum (CV functional groups after the laser transfer. The specific topography of the deposited films involved a uniform thin coating together with several aggregates of bio-functionalized magnetite particles covering the G-tubes. Cytotoxicity assays showed an increase of the G-tube surface biocompatibility after Fe3O4@CV treatment, allowing a normal development of endothelial cells up to five days of incubation. Microbiological assays on nanoparticle-modified G-tube surfaces have proved an improvement of anti-adherent properties, significantly reducing both Gram negative and Gram positive bacteria colonization.

  19. S3T working group. Report 1: group aims

    International Nuclear Information System (INIS)

    Pouey, M.

    1983-04-01

    The work group S3T which is aimed to designing and developing devices using unconventional holographic optics is presented. These devices find applications that are classified here in four items high resolution spectrometers, high definition imaging, high flux devices, metrology and interferometry. The problems to solve and the aims of the group in each of these cases are presented. Three synthesis of lectures are in this report. The main one concerns stigmatism conditions of concave holographic gratings used in normal incidence. This new process of focusing is very interesting for hot plasma diagnostics [fr

  20. Fish Otolith Growth in 1g and 3g Depends on the Gravity Vector

    Science.gov (United States)

    Anken, R. H.; Werner, K.; Breuer, J.; Rahmann, H.

    Size and asymmetry (size difference between the left and the right side) as well as calcium (Ca) content of inner ear otoliths of larval cichlid fish Oreochromis mossambicus were determined after a long-term stay at hypergravity conditions (3g; centrifuge). Both utricular and saccular otoliths (lapilli and sagittae, respectively) were significantly smaller after hyper-g exposure as compared to parallely raised 1g-control specimens and the absolute amount of otolith-Ca was diminished. The asymmetry of sagittae was significantly increased in the experimental animals, whereas the respective asymmetry concerning lapilli was markedly decreased. In the course of another experiment, larvae were raised in aquarium hatch baskets, from which one was placed directly above aeration equipment, which resulted in random water circulation shifting the fish around (``shifted'' specimens). The lapillar asymmetry of the ``stationary'' specimens showed a highly significant increase during early development when larvae were forced to lay on their sides due to their prominent yolk-sacs. In later developmental stages, when they began to swim freely, a dramatic decrease in lapillar asymmetry was apparent. Taken together with own previous findings according to which otolith growth stops after vestibular nerve transection, the results presented here suggest that the growth and the development of bilateral asymmetry of otoliths is guided by the environmental gravity vector, obviously involving a feedback loop between the brain and the inner ear

  1. [Changes to diagnosis-related groups in urology in 2007. Urology in the G-DRG-System 2007].

    Science.gov (United States)

    Wenke, A; Franz, D; Pühse, G; Hertle, L; Roeder, N

    2008-02-01

    The German DRG (dose-related groups) system is updated each year by the institution dealing with the remuneration in hospitals (InEK). Once again, the German Spcoety for Urology has supported the adjustment process in a constructive manner. Analysis of the changes and their implications is highly significant for urology. This article describes and discusses the main changes in the system for the specialty of urology insofar as they concern the structure of the DRG system and the catalogues of diagnoses (ICD) and of procedures (OPS). The 2007 edition of the DRG system leads to numerous changes for urology. There are new OPS codes for partial resection of the kidney, treatment of urinary incontinence and radical resection in the pelvis minor. Additional payment for implantation of a prosthetic penis is divided with reference to the type of prosthesis. At DRG level, new DRG splits are found depending on the PCCL and patient age. Combination operations on the bladder and bowel and on the male genitalia are assigned to newly established DRGs. The changes described enhance the professional accuracy of the representations of urological care provision. New strategies designed to solve problems in representation have been established (e.g. multi-step interventions). Various problems persist, e.g. those of operations on the penis (DRG M03Z) and the need for more finely defined representation of laser treatment in urology. In the short term practicable solutions to the problem of improving the quality of representation are needed.

  2. PAI-1 4G/5G polymorphism and plasma levels association in patients with coronary artery disease.

    Science.gov (United States)

    Lima, Luciana Moreira; Carvalho, Maria das Graças; Fonseca Neto, Cirilo Pereira; Garcia, José Carlos Faria; Sousa, Marinez Oliveira

    2011-12-01

    Type-1 plasminogen activator inhibitor (PAI-1) 4G/5G polymorphism may influence the PAI-1 expression. High plasma levels of PAI-1 are associated with coronary artery disease (CAD). This study investigated the influence of PAI-1 4G/5G polymorphism on plasma PAI-1 levels and its association with CAD assessed by coronary angiography. Blood sample of 35 individuals with angiographically normal coronary arteries, 31 individuals presenting mild/moderate atheromatosis, 57 individuals presenting severe atheromatosis and 38 healthy individuals (controls) were evaluated. In patients and controls, the PAI-1 4G/5G polymorphism was determined by PCR amplification using allele-specific primers. Plasma PAI-1 levels were quantified by ELISA assay (American Diagnostica). No difference was found between groups regarding age, gender and body mass index. Plasma PAI-1 levels and 4G/4G genotype frequency were significantly higher in the severe atheromatosis group compared to the other groups (p5G/5G genotype (r=0.02, p=0.4511). In addition, in a multiple logistic regression model, adjusted for all the other variables, PAI-1 was observed to be independently associated with CAD > 70% (p<0.001). The most important finding of this study was the association between 4G/4G genotype, high plasma PAI-1 levels and coronary stenosis higher than 70% in Brazilian individuals. Whether high plasma PAI-1 levels are a decisive factor for atherosclerosis worsening or it is a consequence remains to be established.

  3. Autoantibodies Specifically Against β1 Adrenergic Receptors and Adverse Clinical Outcome in Patients With Chronic Systolic Heart Failure in the β-Blocker Era: The Importance of Immunoglobulin G3 Subclass.

    Science.gov (United States)

    Nagatomo, Yuji; Li, Daniel; Kirsop, Jennifer; Borowski, Alan; Thakur, Akanksha; Tang, W H Wilson

    2016-06-01

    To elucidate the prevalence and role of β1 adrenergic receptor autoantibodies (β1AR-AAb) belonging to the immunoglobulin (Ig)G3 subclass in patients with heart failure (HF) treated with β-adrenergic blockers. Several cardiac AAbs have been reported to be present in sera from patients with dilated cardiomyopathy and other etiologies. Among AAbs, those recognizing β1AR-AAbs show agonist-like effects, have detrimental effects on cardiomyocytes, and may induce persistent myocardial damage. We quantify total IgG and IgG3 subclass β1AR-AAb in subjects with chronic stable HF with long-term follow-up. In our study cohort of 121 subjects, non-IgG31AR-AAb and IgG31AR-AAb were found to be positive in 20 (17%) and 26 patients (21%), respectively. The positive rate of IgG31AR-AAb was significantly higher for those with nonischemic compared with ischemic HF etiology (27% vs 8%, P = .01), but the positive rate for non-IgG31AR-AAb was similar between the 2 groups (18% vs 16%, respectively, P = NS). There were no significant differences in clinical and echocardiographic measures among total β1AR-AAb negative, non-IgG31AR-AAb positive, and IgG31AR-AAb positive groups at baseline. During 2.2 ± 1.2 years of follow-up, we observed similar rates of the composite endpoint of all-cause mortality, cardiac transplantation, or hospitalization resulting from HF between total IgG1AR-AAb negative and positive patients. However, the composite endpoint events were significantly more common in the patients without than in those with IgG31AR-AAb (P = .048, log-rank test). Presence of IgG31AR-AAb, not total IgG, was associated with paradoxically more favorable outcomes in our cohort of patients with chronic systolic HF largely treated by β-blockers. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. The establishment of RIA method for the assessment of soluble intracellular adhesion molecule-1 and its clinical application

    International Nuclear Information System (INIS)

    Zhang Zhiyou; Fang Peihua; Lu Mei; Gao Shuo

    2002-01-01

    Objective: To establish the radioimmunoassay (RIA) method for the assessment of soluble intracellular adhesion molecule-1 (sICAM-1) and to apply it in clinical evaluation of Graves' disease (GD). Methods: The rabbits were immunized by sICAM-1 to prepare the specific polyclonal antibody for the sICAM-1 RIA. The study population was composed of 400 healthy people, 56 simple goiter patients, 312 GD patients before treatment, 445 GD patients after treatment with antithyroid drug whose thyroid functional parameters were normal, 36 GD patients before and after 131 I treatment, 93 GD patients before and after antithyroid drug treatment, 6 GD patients before and after thyroidectomy, 52 relapse GD patients and their serum sICAM-1 levels were measured. Results: The sensitivity of sICAM-1 RIA was 66.53 μg/L. The non-specific binding was less than 8%. The intra-assay coefficients of variation (CV) were 4.25%, 4.35%, 3.99% (n=6) and the inter-assay CV were 5.55%, 2.82%, 3.48% (n=6) for 110, 220, 320 μg/L, respectively. The average recovery rate of the method was 100.88%. The serum level of sICAM-1g/L) in normal group was 168.43+-72.46 (x-bar+-2s) and in the GD groups of before and after antithyroid drug treatment the serum levels were both higher than that in normal groups (P 0.05); in the before treatment GD group it was higher than that in after treatment group (P 131 I treatment and antithyroid drug treatment GD groups, the levels were all decreased markedly after treatment (P<0.05); in the relapse GD group, it was higher than in the GD group with normal thyroid functional parameters (P<0.01). Conclusions: sICAM-1 RIA has been established successfully. The results show that sICAM-1 may be an important indicator for estimating effects of therapy, the relapse of GD and the necessity of drug administration ceasing

  5. An early 'handwritten' shell exchange catalogue of the Leiden Museum, with notes on the collectors Rethaan Macaré and Tischbein

    NARCIS (Netherlands)

    Bruggen, van A.C.

    2013-01-01

    A ‘handwritten’ (lithographed) shell exchange catalogue of the National Museum of Natural History, Leiden (The Netherlands), dated 1850 and containing 864 nominal taxa (861 molluscs and 3 brachiopods), is discussed in the context of the history of the museum. This catalogue must have been

  6. Restful Implementation of Catalogue Service for Geospatial Data Provenance

    Science.gov (United States)

    Jiang, L. C.; Yue, P.; Lu, X. C.

    2013-10-01

    Provenance, also known as lineage, is important in understanding the derivation history of data products. Geospatial data provenance helps data consumers to evaluate the quality and reliability of geospatial data. In a service-oriented environment, where data are often consumed or produced by distributed services, provenance could be managed by following the same service-oriented paradigm. The Open Geospatial Consortium (OGC) Catalogue Service for the Web (CSW) is used for the registration and query of geospatial data provenance by extending ebXML Registry Information Model (ebRIM). Recent advance of the REpresentational State Transfer (REST) paradigm has shown great promise for the easy integration of distributed resources. RESTful Web Service aims to provide a standard way for Web clients to communicate with servers based on REST principles. The existing approach for provenance catalogue service could be improved by adopting the RESTful design. This paper presents the design and implementation of a catalogue service for geospatial data provenance following RESTful architecture style. A middleware named REST Converter is added on the top of the legacy catalogue service to support a RESTful style interface. The REST Converter is composed of a resource request dispatcher and six resource handlers. A prototype service is developed to demonstrate the applicability of the approach.

  7. Security in a Replicated Metadata Catalogue

    CERN Document Server

    Koblitz, B

    2007-01-01

    The gLite-AMGA metadata has been developed by NA4 to provide simple relational metadata access for the EGEE user community. As advanced features, which will be the focus of this presentation, AMGA provides very fine-grained security also in connection with the built-in support for replication and federation of metadata. AMGA is extensively used by the biomedical community to store medical images metadata, digital libraries, in HEP for logging and bookkeeping data and in the climate community. The biomedical community intends to deploy a distributed metadata system for medical images consisting of various sites, which range from hospitals to computing centres. Only safe sharing of the highly sensitive metadata as provided in AMGA makes such a scenario possible. Other scenarios are digital libraries, which federate copyright protected (meta-) data into a common catalogue. The biomedical and digital libraries have been deployed using a centralized structure already for some time. They now intend to decentralize ...

  8. Post dural puncture headache after spinal anaesthesia for caesarean section: a comparison of 25 g Quincke, 27 g Quincke and 27 g Whitacre spinal needles.

    Science.gov (United States)

    Shaikh, Jan Muhammad; Memon, Amna; Memon, Muhammad Ali; Khan, Majida

    2008-01-01

    To compare the frequency and severity of post dural puncture headache in obstetric patients using 25G Quincke, 27G Quincke and 27G Whitacre spinal needles. Comparative, randomized, double-blind, interventional study. Liaquat University Hospital Hyderabad from October 2005 to December 2006. 480 ASA I-II full term pregnant women, 18 to 45 years of age, scheduled for elective Caesarean section, under spinal anaesthesia, were randomized into three groups: Group I (25G Quincke spinal needle: n=168), Group II (27G Quincke spinal needle: n=160) and Group III (27G Whitacre spinal needle: n=152). Spinal anaesthesia was performed with 1.5-2.0 ml 0.75% hyperbaric bupivacaine using 25G Quincke spinal needle (Group I), 27G Quincke spinal needle (Group II) and 27G Whitacre spinal needle (Group III) at L3-4 inter-vertebral space. Each patient was assessed daily for four consecutive days following Caesarean section. Frequency and severity and of postdural puncture headache (PDPH) were recorded. Data were analyzed using SPSS-11. Frequency of PDPH following the use of 25G Quincke (Group I), 27G Quincke (Group II) and 27G Whitacre (Group III) spinal needles was 8.3% (14/168), 3.8% (6/160) and 2.0% (3/152) respectively. In Group I, PDPH was mild in 5 patients, moderate in 7 patients and severe in 2 patients. In Group II, it was mild in 2, moderate in 3 and severe in 1 patient. In group III, it was mild in 2 and moderate in 1 patient. Severe PDPH did not occur in Group III. Most of the patients with PDPH developed it on 1st and 2nd postoperative day. When using a 27G Whitacre spinal needle, the frequency and severity of PDPH was significantly lower than when a 25G Quincke or 27G Quincke needle was used.

  9. Investigation of Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G promoter polymorphism in Indian venous thrombosis patients: A case-control study.

    Science.gov (United States)

    Prabhudesai, Aniket; Shetty, Shrimati; Ghosh, Kanjaksha; Kulkarni, Bipin

    2017-09-01

    The role of PAI-1 4G/5G polymorphism in venous thrombosis has been contradictory. PAI-1 4G/4G genotype is associated with elevated levels of PAI-1 resulting in a hypofibrinolytic state and a higher thrombotic risk. In this study, the distribution of genotypes and frequency of alleles of the 4G/5G polymorphism of PAI-1 gene in Indian patients with different types of venous thrombosis was investigated for its role in development of thrombosis. A total of 87 portal vein thrombosis (PVT), 71 Budd-Chiari syndrome (BCS), 156 cerebral vein thrombosis (CVT), and 163 deep vein thrombosis (DVT) patients were studied alongside 251 healthy controls for the PAI-1 4G/5G polymorphism by allele-specific PCR. Frequency of 4G/4G genotype was higher in all groups in comparison with controls. 4G/4G was associated with PVT risk (OR=2.51, 95% CI=1.29-4.96, P=.0075), BCS risk (OR=5.98, 95% CI=2.68-13.42, P<.0001), and DVT risk (OR=1.75, 95% CI=0.98-3.02, P=.0225). This is the first case-control study from India establishing PAI-1 4G/4G as a strong risk factor for abdominal thrombosis (PVT and BCS). Statistically significant association was not found between 4G/4G genotype and CVT risk. PAI-1 4G/4G is a strong risk factor for venous thrombosis in Indian patients and should be included in laboratory testing panel of thrombophilia. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  10. Variation in GYS1 interacts with exercise and gender to predict cardiovascular mortality.

    Directory of Open Access Journals (Sweden)

    Jenny Fredriksson

    Full Text Available BACKGROUND: The muscle glycogen synthase gene (GYS1 has been associated with type 2 diabetes (T2D, the metabolic syndrome (MetS, male myocardial infarction and a defective increase in muscle glycogen synthase protein in response to exercise. We addressed the questions whether polymorphism in GYS1 can predict cardiovascular (CV mortality in a high-risk population, if this risk is influenced by gender or physical activity, and if the association is independent of genetic variation in nearby apolipoprotein E gene (APOE. METHODOLOGY/PRINCIPAL FINDINGS: Polymorphisms in GYS1 (XbaIC>T and APOE (-219G>T, epsilon2/epsilon3/epsilon4 were genotyped in 4,654 subjects participating in the Botnia T2D-family study and followed for a median of eight years. Mortality analyses were performed using Cox proportional-hazards regression. During the follow-up period, 749 individuals died, 409 due to CV causes. In males the GYS1 XbaI T-allele (hazard ratio (HR 1.9 [1.2-2.9], T2D (2.5 [1.7-3.8], earlier CV events (1.7 [1.2-2.5], physical inactivity (1.9 [1.2-2.9] and smoking (1.5 [1.0-2.3] predicted CV mortality. The GYS1 XbaI T-allele predicted CV mortality particularly in physically active males (HR 1.7 [1.3-2.0]. Association of GYS1 with CV mortality was independent of APOE (219TT/epsilon4, which by its own exerted an effect on CV mortality risk in females (2.9 [1.9-4.4]. Other independent predictors of CV mortality in females were fasting plasma glucose (1.2 [1.1-1.2], high body mass index (BMI (1.0 [1.0-1.1], hypertension (1.9 [1.2-3.1], earlier CV events (1.9 [1.3-2.8] and physical inactivity (1.9 [1.2-2.8]. CONCLUSIONS/SIGNIFICANCE: Polymorphisms in GYS1 and APOE predict CV mortality in T2D families in a gender-specific fashion and independently of each other. Physical exercise seems to unmask the effect associated with the GYS1 polymorphism, rendering carriers of the variant allele less susceptible to the protective effect of exercise on the risk of CV death

  11. [G894T (NOS3) and G1958A (MTHFD1) gene polymorphisms and risk of ischemic heart disease in Yucatan, Mexico].

    Science.gov (United States)

    García-González, Igrid; Solís-Cárdenas, Alberto de Jesús; Flores-Ocampo, Jorge A; Alejos-Mex, Ricardo; Herrera-Sánchez, Luis Fernando; González-Herrera, Lizbeth Josefina

    2015-01-01

    Cardiovascular medicine is focused on the search for genetic risk markers with predictive and/or prognostic value. Among the genetic variants of interest are G894T endothelial nitric oxide synthase and G1958A methylenetetrahydrofolate dehydrogenase1 gene polymorphisms. The aim of this study was to determine the possible association between these polymorphisms and ischemic heart disease in patients from Southern of Mexico (Yucatán). Case-control study matched by age, sex and origin was designed. We studied 98 patients with coronary disease and 101 controls. Participants were evaluated for the usual risk factors. The polymorphisms were identified using the polymerase chain reaction/restriction fragment length polymorphism analysis. Informed consent was obtained from all participants. The G894T and G1958A polymorphisms were not associated with ischemic heart disease, however, the TT genotype (G894T) was associated with the angina (OR=10.2; 95%CI, 1.51-68.8; p=0.025). The genotype GT (G894T) was the most frequent in patients with family history of coronary artery disease. Multiple logistic regression analysis identified smoking (OR=5.21; 95%CI, 2.1-12.9; p=0.000), hypertension (OR=3.54; 95%CI, 1.47-8.56; p=0.005) and obesity (OR=1.16; 95%CI, 1.1-1.27; p=0.001) as risk factors predicting the ischemic heart disease. The G894T and G1958A polymorphisms showed not association with ischemic heart disease. However, homozygosis for the 894T allele (NOS3) confers at risk to develop angina on Yucatán. Copyright © 2014 Sociedad Española de Arteriosclerosis. Published by Elsevier España. All rights reserved.

  12. Importance of winter pea cv. Maksimirski ozimi in production of the milk on family farms in Croatia

    Directory of Open Access Journals (Sweden)

    Darko Uher

    2008-12-01

    Full Text Available Two year field trials (1999-2001 were carried out to determine the effect of seed winter pea inoculation and nitrogen top-dressing on number and nodule dry weight g/plant of pea root and also on the yield of winter pea cv. Maksimirski ozimi and triticale cv. Clercal mixture. Just before sowing the inoculation of pea seeds was performed by the variety of Rhizobium leguminosarum bv. viciae which is part of the microbial collection of the Department of Microbiology at the Faculty of Agriculture University of Zagreb. The highest total nodule number on pea root (28 nodule/plant was determined on the inoculated variant 2 as well as nodule dry weight (0,175 g/plant. Average pea seed yield were ranging from 1327 kg ha-1 (control up to 1825 kg ha-1 (inoculation. Average triticale grain yield were ranging from 2375 kg ha-1 (control up to 3345 kg ha-1 (nitrogen top-dressing. Average total grain yield of winter peas in mixture triticale were ranging from 3702 kg ha-1 (control up to 5045 kg ha-1 (nitrogen top-dressing. This paper and given results are a humble contribution to the research of pea growth in the Republic of Croatia.

  13. E-Catalogue “Knowledge Management Practices in Nuclear Organizations”

    International Nuclear Information System (INIS)

    Sheveleva, S.; Pasztory, Z.

    2014-01-01

    The objectives of NKM E-Catalogue: Many nuclear organizations from IAEA Member States have considerable experiences and excellent achievements in the development of Knowledge Management Systems. Depending on organization’s strategy and type of business, they choose various methods and tools of knowledge management for realizing their aims. This catalogue will be available to all Member States interested in learning about collected knowledge management practices in order to enhance their own knowledge management programmes

  14. Vaccine potential of recombinant cathepsinL1G against Fasciola gigantica in mice.

    Science.gov (United States)

    Changklungmoa, Narin; Phoinok, Natthacha; Yencham, Chonthicha; Sobhon, Prasert; Kueakhai, Pornanan

    2016-08-15

    In this study, we characterized and investigated the vaccine potential of FgCatL1G against Fasciola gigantica infection in mice. Recombinant mature FgCatL1G (rmFgCatL1G) was expressed in Escherichia coli BL21. The vaccination was performed in Imprinting Control Region (ICR) mice (n=10) by subcutaneous injection with 50μg of rmFgCatL1G combined with Freund's adjuvant. Two weeks after the second boost, mice were infected with 15 metacercariae by the oral route. The percents of protection of rmFgCatL1G vaccine were estimated to be 56.5% and 58.3% when compared with non vaccinated-infected and adjuvant-infected controls, respectively. Antibodies in the immune sera of vaccinated mice were shown by immunoblot to react with the native FgCatL1s in the extract of all stages of parasites and rmFgCatL1H, recombinant pro - FgCatL1 (rpFgCatL1). By immunohistochemistry, the immune sera also reacted with FgCatL1s in the caecal epithelial cells of the parasites. The levels of IgG1 and IgG2a in the immune sera, which are indicative of Th2 and Th1 immune responses, were also increased with IgG1 predominating. The levels of serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT) in rmFgCatL1G-immunized group showed no significant difference from the control groups, but pathological lesions of livers in rmFgCatL1G-immunized group showed significant decrease when compared to the control groups. This study indicates that rmFgCatL1G has a vaccine potential against F. gigantica in mice, and this potential will be tested in larger livestock animals. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. A search for southern ultracool dwarfs in young moving groups

    Directory of Open Access Journals (Sweden)

    Deacon N.R.

    2011-07-01

    Full Text Available We have constructed an 800-strong red object catalogue by cross-referencing optical and infrared catalogues with an extensive proper motion catalogue compiled for red objects in the southern sky to obtain proper motions. We have applied astrometric and photometric constraints to the catalogue in order to select ultracool dwarf moving group candidates. 132 objects were found to be candidates of a moving group. From this candidate list we present initial results. Using spectroscopy we have obtained reliable spectral types and space motions, and by association with moving groups we can infer an age and composition. the further study of the remainder of our candidates will provide a large sample of young brown dwarfs and confirmed members will provide benchmark ultracool dwarfs. These will make suitable targets of AO planet searches.

  16. White dwarf-main sequence binaries from LAMOST: the DR5 catalogue

    Science.gov (United States)

    Ren, J.-J.; Rebassa-Mansergas, A.; Parsons, S. G.; Liu, X.-W.; Luo, A.-L.; Kong, X.; Zhang, H.-T.

    2018-03-01

    We present the data release (DR) 5 catalogue of white dwarf-main sequence (WDMS) binaries from the Large Area Multi-Object fiber Spectroscopic Telescope (LAMOST). The catalogue contains 876 WDMS binaries, of which 757 are additions to our previous LAMOST DR1 sample and 357 are systems that have not been published before. We also describe a LAMOST-dedicated survey that aims at obtaining spectra of photometrically-selected WDMS binaries from the Sloan Digital Sky Survey (SDSS) that are expected to contain cool white dwarfs and/or early type M dwarf companions. This is a population under-represented in previous SDSS WDMS binary catalogues. We determine the stellar parameters (white dwarf effective temperatures, surface gravities and masses, and M dwarf spectral types) of the LAMOST DR5 WDMS binaries and make use of the parameter distributions to analyse the properties of the sample. We find that, despite our efforts, systems containing cool white dwarfs remain under-represented. Moreover, we make use of LAMOST DR5 and SDSS DR14 (when available) spectra to measure the Na I λλ 8183.27, 8194.81 absorption doublet and/or Hα emission radial velocities of our systems. This allows identifying 128 binaries displaying significant radial velocity variations, 76 of which are new. Finally, we cross-match our catalogue with the Catalina Surveys and identify 57 systems displaying light curve variations. These include 16 eclipsing systems, two of which are new, and nine binaries that are new eclipsing candidates. We calculate periodograms from the photometric data and measure (estimate) the orbital periods of 30 (15) WDMS binaries.

  17. Qualidade de pêssegos cv. "Eldorado" tratados com aminoetoxivinilglicina e ethephon e armazenados em atmosfera controlada Quality of cv. 'Eldorado' peach fruit treated with aminoethoxyvinylglycine and ethephon and stored in controlled atmosphere

    Directory of Open Access Journals (Sweden)

    Auri Brackmann

    2007-02-01

    Full Text Available O objetivo desse trabalho foi avaliar o efeito da combinação da aplicação em pré-colheita de aminoetoxivinilglicina (AVG e de ethephon com o armazenamento em atmosfera controlada (AC na manutenção da qualidade e na redução de desordens causadas pela baixa temperatura em pêssegos cv. "Eldorado", visando ao transporte marítimo. Os tratamentos constituíram-se da aplicação de AVG (125g ha-1 e 250g ha-1 aos 15 ou 21 dias antes da colheita, de ethephon (140g ha-1 aos sete dias antes da colheita e do controle (sem aplicação de produtos, combinados com duas condições de armazenamento em AC 1,0kPa de O2 + 3,0kPa de CO2 e 2,0kPa de O2 + 5,0kPa de CO2 a 0°C. Após 24 dias de armazenamento em AC e de mais dois e quatro dias a 15°C, simulando o período médio de transporte marítimo até a Europa, observou-se que a aplicação de ethephon aumentou a produção de etileno e reduziu a acidez titulável e a firmeza da polpa dos frutos, acelerando o amadurecimento. A aplicação de AVG na pré-colheita não retardou o amadurecimento dos frutos, porém a aplicação 125g ha-1 de AVG aos 15 dias antes da colheita reduziu a incidência de escurecimento da polpa, em relação ao controle e ao ethephon. Além disso, a condição de atmosfera controlada com 2,0kPa de O2 + 5,0kPa de CO2 permitiu maior acidez titulável e menor incidência de escurecimento da polpa.The effect of preharvest application of aminoethoxyvinylglycine (AVG and ethephon combined with controlled atmosphere (CA storage conditions on peach fruit (cv. Eldorado quality maintenance and chilling injury prevention was investigated, aiming at the maritime transport. Treatments evaluated were preharvest application of AVG (125g ha-1 and 250g ha-1 at 15 or 21 days before harvest, ethephon (140g ha-1 7 days before harvest, and control, combined with two CA conditions (1.0kPa O2 + 3.0kPa CO2 and 2.0kPa O2 + 5.0kPa CO2 at 0°C. After 24 days of CA storage plus 2 and 4 days of shelf

  18. Effects of Grapevine Leafroll associated Virus 3 (GLRaV-3) and duration of infection on fruit composition and wine chemical profile of Vitis vinifera L. cv. Sauvignon blanc.

    Science.gov (United States)

    Montero, R; Mundy, D; Albright, A; Grose, C; Trought, M C T; Cohen, D; Chooi, K M; MacDiarmid, R; Flexas, J; Bota, J

    2016-04-15

    In order to determine the effects of Grapevine Leafroll associated Virus 3 (GLRaV-3) on fruit composition and chemical profile of juice and wine from Vitis vinifera L. cv. Sauvignon blanc grown in New Zealand, composition variables were measured on fruit from vines either infected with GLRaV-3 (established or recent infections) or uninfected vines. Physiological ripeness (20.4°Brix) was the criterion established to determine the harvest date for each of the three treatments. Date of grape ripeness was strongly affected by virus infection. In juice and wine, GLRaV-3 infection prior to 2008 reduced titratable acidity compared with the uninfected control. Differences observed in amino acids from the three infection status groups did not modify basic wine chemical properties. In conclusion, GLRaV-3 infection slowed grape ripening, but at equivalent ripeness to result in minimal effects on the juice and wine chemistry. Time of infection produced differences in specific plant physiological variables. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. 3GPP SA2 architecture and functions for 5G mobile communication system

    Directory of Open Access Journals (Sweden)

    Junseok Kim

    2017-03-01

    Full Text Available The on-going development of Fifth Generation (5G mobile communication technology will be the cornerstone for applying Information and Communication Technology (ICT to various fields, e.g., smart city, smart home, connected car, etc. The 3rd Generation Partnership Project (3GPP, which has developed the most successful standard technologies in the mobile communication market such as Universal Mobile Telecommunication System (UMTS and Long Term Evolution (LTE, is currently carrying out the standardization of both 5G access network system and 5G core network system at the same time. Within 3GPP, Service and System Aspects Working Group 2 (SA2 is responsible for identifying the main functions and entities of the network. In December 2016, the 3GPP SA2 group finalized the first phase of study for the architecture and main functions of 5G mobile communication system under the study item of Next Generation system (NextGen. Currently, normative standardization is on-going based on the agreements made in the NextGen Phase 1 study. In this paper, we present the architecture and functions of 5G mobile communication system agreed in the NextGen study.

  20. Sr and Pb isotopic composition of five USGS glasses (BHVO-2G, BIR-1G, BCR-2G, TB-1G, NKT-1G)

    NARCIS (Netherlands)

    Elburg, M.A.; Vroon, P.Z.; van der Wagt, R.A.C.A.; Tchalikian, A.

    2005-01-01

    Sr isotopic compositions and Rb/Sr ratios of three USGS glasses (BHVO-2G, BIR-1G, BCR-2G) are identical to those of the original USGS reference materials. NKT-1G and TB-1G give values of 0.70351 and 0.70558, respectively. Pb isotopic ratios were measured by the standard-sample bracketing technique

  1. Planck 2013 results. XXVIII. The Planck Catalogue of Compact Sources

    CERN Document Server

    Ade, P.A.R.; Armitage-Caplan, C.; Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Baccigalupi, C.; Banday, A.J.; Barreiro, R.B.; Bartlett, J.G.; Battaner, E.; Benabed, K.; Benoit, A.; Benoit-Levy, A.; Bernard, J.P.; Bersanelli, M.; Bielewicz, P.; Bobin, J.; Bock, J.J.; Bonaldi, A.; Bonavera, L.; Bond, J.R.; Borrill, J.; Bouchet, F.R.; Bridges, M.; Bucher, M.; Burigana, C.; Butler, R.C.; Cardoso, J.F.; Carvalho, P.; Catalano, A.; Challinor, A.; Chamballu, A.; Chen, X.; Chiang, L.Y.; Chiang, H.C.; Christensen, P.R.; Church, S.; Clemens, M.; Clements, D.L.; Colombi, S.; Colombo, L.P.L.; Couchot, F.; Coulais, A.; Crill, B.P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R.D.; Davis, R.J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Delouis, J.M.; Desert, F.X.; Dickinson, C.; Diego, J.M.; Dole, H.; Donzelli, S.; Dore, O.; Douspis, M.; Dupac, X.; Efstathiou, G.; Ensslin, T.A.; Eriksen, H.K.; Finelli, F.; Forni, O.; Frailis, M.; Franceschi, E.; Galeotta, S.; Ganga, K.; Giard, M.; Giardino, G.; Giraud-Heraud, Y.; Gonzalez-Nuevo, J.; Gorski, K.M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Hansen, F.K.; Hanson, D.; Harrison, D.; Henrot-Versille, S.; Hernandez-Monteagudo, C.; Herranz, D.; Hildebrandt, S.R.; Hivon, E.; Hobson, M.; Holmes, W.A.; Hornstrup, A.; Hovest, W.; Huffenberger, K.M.; Jaffe, T.R.; Jaffe, A.H.; Jones, W.C.; Juvela, M.; Keihanen, E.; Keskitalo, R.; Kisner, T.S.; Kneissl, R.; Knoche, J.; Knox, L.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lahteenmaki, A.; Lamarre, J.M.; Lasenby, A.; Laureijs, R.J.; Lawrence, C.R.; Leahy, J.P.; Leonardi, R.; Leon-Tavares, J.; Leroy, C.; Lesgourgues, J.; Liguori, M.; Lilje, P.B.; Linden-Vornle, M.; Lopez-Caniego, M.; Lubin, P.M.; Macias-Perez, J.F.; Maffei, B.; Maino, D.; Mandolesi, N.; Maris, M.; Marshall, D.J.; Martin, P.G.; Martinez-Gonzalez, E.; Masi, S.; Matarrese, S.; Matthai, F.; Mazzotta, P.; McGehee, P.; Meinhold, P.R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschenes, M.A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Naselsky, P.; Nati, F.; Natoli, P.; Negrello, M.; Netterfield, C.B.; Norgaard-Nielsen, H.U.; Noviello, F.; Novikov, D.; Novikov, I.; O'Dwyer, I.J.; Osborne, S.; Oxborrow, C.A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, T.J.; Perdereau, O.; Perotto, L.; Perrotta, F.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Popa, L.; Poutanen, T.; Pratt, G.W.; Prezeau, G.; Prunet, S.; Puget, J.L.; Rachen, J.P.; Reach, W.T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Roudier, G.; Rowan-Robinson, M.; Rubino-Martin, J.A.; Rusholme, B.; Sandri, M.; Santos, D.; Savini, G.; Schammel, M.P.; Scott, D.; Seiffert, M.D.; Shellard, E.P.S.; Spencer, L.D.; Starck, J.L.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sunyaev, R.; Sureau, F.; Sutton, D.; Suur-Uski, A.S.; Sygnet, J.F.; Tauber, J.A.; Tavagnacco, D.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Turler, M.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Varis, J.; Vielva, P.; Villa, F.; Vittorio, N.; Wade, L.A.; Walter, B.; Wandelt, B.D.; Yvon, D.; Zacchei, A.; Zonca, A.

    2014-01-01

    The Planck Catalogue of Compact Sources (PCCS) is the catalogue of sources detected in the first 15 months of Planck operations, the "nominal" mission. It consists of nine single-frequency catalogues of compact sources, both Galactic and extragalactic, detected over the entire sky. The PCCS covers the frequency range 30--857\\,GHz with higher sensitivity (it is 90% complete at 180 mJy in the best channel) and better angular resolution (from ~33' to ~5') than previous all-sky surveys in this frequency band. By construction its reliability is >80% and more than 65% of the sources have been detected at least in two contiguous Planck channels. In this paper we present the construction and validation of the PCCS, its contents and its statistical characterization.

  2. The Availability of MeSH in Vendor-Supplied Cataloguing Records, as Seen Through the Catalogue of a Canadian Academic Health Library

    Directory of Open Access Journals (Sweden)

    Pamela S. Morgan

    2007-09-01

    Full Text Available This study examines the prevalence of medical subject headings in vendor-supplied cataloguing records for publications contained within aggregated databases or publisher collections. In the first phase, the catalogue of one Canadian academic medical library was examined to determine the extent to which medical subject headings (MeSH are available in the vendor-supplied records. In the second phase, these results were compared to the catalogues of other Canadian academic medical libraries in order to reach a generalization regarding the availability of MeSH headings for electronic resources. MeSH was more widespread in records for electronic journals but was noticeably lacking in records for electronic monographs, and for Canadian publications. There is no standard for ensuring MeSH are assigned to monograph records for health titles and there is no library in Canada with responsibility for ensuring that Canadian health publications receive Medical Subject Headings. It is incumbent upon libraries using MeSH to ensure that vendors are aware of this need when purchasing record sets.

  3. Association of the plasminogen activator inhibitor-1 (PAI-1) Gene -675 4G/5G and -844 A/G promoter polymorphism with risk of keloid in a Chinese Han population.

    Science.gov (United States)

    Wang, Yongjie; Long, Jianhong; Wang, Xiaoyan; Sun, Yang

    2014-10-28

    A keloid is pathological scar caused by aberrant response to skin injuries, characterized by excessive accumulation of histological extracellular matrix, and occurs in genetically susceptible individuals. Plasminogen activator inhibitor-1 (PAI-1) has been implicated in the pathogenesis of keloid. We investigated the association between PAI-1 polymorphisms and plasma PAI-1 level with keloid risk. A total of 242 Chinese keloid patients and 207 controls were enrolled in this study. Polymerase chain reaction-restriction technique was used to determine PAI-1 promoter polymorphism (-675 4G/5G and -844 A/G) distribution. Plasma PAI-1 levels were detected using enzyme-linked immunosorbent assay (ELISA). There was a statistically significant difference in the distribution of PAI-1 -675 4G/5G polymorphism between keloid patients and healthy controls. 4G/4G carriers were more likely to develop keloid. In contrast, the -844 A/G polymorphism distribution did not vary significantly between keloid patients and controls. The keloid patients group had a significantly higher plasma PAI-1 level than the control group. In the -675 4G/4G carrier population, the plasma PAI-1 levels were significant higher in keloid patients compared with controls. Our study provides evidence that PAI-1 promoter polymorphism -675 4G/5G and plasma PAI-1 level are associated with keloid risk. PAI-1 -675 4G/5G polymorphism may be an important hereditary factor responsible for keloid development in the Chinese Han population.

  4. Efeito de substrato artificial no enraizamento de estacas de calanchoe (Kalanchoe x blossfeldiana cv. singapur, crassulaceae) Artificial substract effect on the rooting of calanchoe (Kalanchoe x blossfeldiana cv. singapur, crassulaceae) cuttings

    OpenAIRE

    A.L. Gonçalves; K. Minami

    1994-01-01

    Dez misturas artificiais foram estudadas para avaliar o efeito sobre o enraizamento de estacas apicais de Kalanchoe x blossfeldiana cv. Singapur, da família Crassulaceae. Essas misturas foram as seguintes: vermiculita + casca de arroz tostada nas proporções 1:1, 2:1 e 3:1; vermiculita + torta de filtro Oliver nas proporções 1:1, 2:1 e 3:1; vermiculita + turfa da região de Atibaia-SP, nas proporções 1:l, 2:le3:l; vermiculita + casca de pinheiro (mistura comercial). Os melhores resultados foram...

  5. Influence of plasminogen activator inhibitor-1 (SERPINE1) 4G/5G polymorphism on circulating SERPINE-1 antigen expression in HCC associated with viral infection.

    Science.gov (United States)

    Divella, Rosa; Mazzocca, Antonio; Gadaleta, Cosimo; Simone, Giovanni; Paradiso, Angelo; Quaranta, Michele; Daniele, Antonella

    2012-01-01

    Hepatocarcinogenesis is heavily influenced by chronic hepatitis B (HBV) and C (HCV) infection. Elevated levels of plasminogen activator inhibitor-1 (SERPINE1/PAI-1) have been reported in patients with hepatocellular carcinoma (HCC) associated with viral infection. The gene encoding SERPINE1 is highly polymorphic and the frequently associated 4/5 guanosine (4G/5G) polymorphism in the gene promoter may influence its expression. Here, we investigated the distribution of genotypes and the frequency of alleles of the 4G/5G polymorphism in patients with HCC, the influence of the 4G/5G polymorphism on plasma SERPINE1 levels and its association with viral infection. A total of 75 patients with HCC were enrolled: 32 (42.6%) were HBV(+)/HCV(+), 11 (14.6%) were only HCV(+), and 32 (42.6%) were negative for both viruses. A control group of healthy donors was also enrolled (n=50). SERPINE1 plasma concentrations were determined by ELISA and the detection of the promoter 4G/5G polymorphism was performed by an allele-specific PCR analysis. We found that the frequency of both the 4G/4G genotype (p=0.02) and the 4G allele (p=0.006) were significantly higher in patients with HCC compared to the control group, and particularly higher in patients with HCC co-infected with HBV(+)/HCV(+) than in those with no viral infection. We also found that patients with the 4G/4G genotype had significantly higher plasma SERPINE1 protein levels when compared with patients with the 4G/5G or 5G/5G genotype (p5G SERPINE1 polymorphism with a higher level of SERPINE1 protein in patients with HCC with HBV(+)/HCV(+) than those without infection, suggest the presence of two distinct pathogenic mechanisms in hepatocarcinogenesis, depending on the etiology.

  6. Nutritional disorder of lettuce cv. Veronica in nutrient solution with suppressed macronutrients

    Directory of Open Access Journals (Sweden)

    Thiago Batista Firmato de Almeida

    2011-06-01

    Full Text Available Lettuce is the most popular of the leafy vegetables. It is known worldwide and its consumption occurs mainly in the natural form. The objective was to evaluate the effect of macronutrient omission on the growth and nutritional status of the lettuce cv. Veronica, and to describe the visual symptoms of nutritional deficiency. The treatments complete consisted of the solution and the individual omission of N, P, K, Ca, Mg and S, under a completely randomized design with three replications. Plants were grown in Hoagland & Arnon, in pots (8L. At 56 days after transplant we evaluated plant height, leaf number, leaf area, SPAD index, dry matter of shoots, roots and whole plant, levels of macronutrients in shoots and roots, and the nature of nutritional disorders. The omission of nutrients affected the growth variables. The nutrients found in lettuce plants from nutrient solution and the complete omission in the shoot were, respectively, N= 23.2 to 9.5, P= 5.4 to 1.3, K= 58,9 to 3.2, Ca= 12.1 to 3.6, Mg= 5.5 to 0.7 and S= 3.2 to 1.5g.kg-1. The omission of macronutrients caused quality losses, since it affected the nutrition of the vegetables and this resulted in morphological changes, reflected as symptoms of deficiency for each nutrient.

  7. EARLY-TYPE GALAXIES AT z = 1.3. I. THE LYNX SUPERCLUSTER: CLUSTER AND GROUPS AT z = 1.3. MORPHOLOGY AND COLOR-MAGNITUDE RELATION

    International Nuclear Information System (INIS)

    Mei, Simona; Raichoor, Anand; Huertas-Company, Marc; Adam Stanford, S.; Rettura, Alessandro; Jee, Myungkook J.; Holden, Brad P.; Illingworth, Garth D.; Postman, Marc; Nakata, Fumiaki; Kodama, Tadayuki; Finoguenov, Alexis; Ford, Holland C.; Rosati, Piero; Tanaka, Masayuki; Koyama, Yusei; Shankar, Francesco; Carrasco, Eleazar R.; Demarco, Ricardo; Eisenhardt, Peter

    2012-01-01

    We confirm the detection of three groups in the Lynx supercluster, at z ≈ 1.3, through spectroscopic follow-up and X-ray imaging, and we give estimates for their redshifts and masses. We study the properties of the group galaxies compared to the two central clusters, RX J0849+4452 and RX J0848+4453. Using spectroscopic follow-up and multi-wavelength photometric redshifts, we select 89 galaxies in the clusters, of which 41 are spectroscopically confirmed, and 74 galaxies in the groups, of which 25 are spectroscopically confirmed. We morphologically classify galaxies by visual inspection, noting that our early-type galaxy (ETG) sample would have been contaminated at the 30%-40% level by simple automated classification methods (e.g., based on Sérsic index). In luminosity-selected samples, both clusters and groups show high fractions of bulge-dominated galaxies with a diffuse component that we visually identified as a disk and which we classified as bulge-dominated spirals, e.g., Sas. The ETG fractions never rise above ≈50% in the clusters, which is low compared to the fractions observed in other massive clusters at z ≈ 1. In the groups, ETG fractions never exceed ≈25%. However, overall bulge-dominated galaxy fractions (ETG plus Sas) are similar to those observed for ETGs in clusters at z ∼ 1. Bulge-dominated galaxies visually classified as spirals might also be ETGs with tidal features or merger remnants. They are mainly red and passive, and span a large range in luminosity. Their star formation seems to have been quenched before experiencing a morphological transformation. Because their fraction is smaller at lower redshifts, they might be the spiral population that evolves into ETGs. For mass-selected samples of galaxies with masses M > 10 10.6 M ☉ within Σ > 500 Mpc –2 , the ETG and overall bulge-dominated galaxy fractions show no significant evolution with respect to local clusters, suggesting that morphological transformations might occur at lower

  8. Analisis Daya Saing untuk Meningkatkan Kualitas Layanan terhadap Pelanggan dengan Pendekatan CRM di CV. BLITZSPOT

    Directory of Open Access Journals (Sweden)

    Suryadi Muhammad

    2017-04-01

    Full Text Available CV. Blitzspot adalah perusahaan yang bergerak di bidang jasa penyediaan layanan internet (internet service provider, yang berkantor pusat di Komplek Padasuka Indah Ruko Blok A-1, Cimahi, Jawa Barat. Berdasarkan hasil wawancara dan hasil observasi pada data transaksi CV. Blitzspot, konsumen CV. Blitzspot yang melakukan transaksi tiap tahunnya selalu berkurang, hal ini dikarenakan konsumen sering membandingkan layanan-layanan yang ditawarkan oleh para pesaing CV. Blitzspot. Bila permasalahan tersebut belum teratasi, konsumen CV. Blitzspot akan menurun tiap tahunnya dan akan selalu berpindah ke pesaing CV. Blitzspot. Direktur Utama CV. Blitzspot ingin menganalisis daya saing untuk menentukan layanan-layanan yang akan diberikan kepada pelanggan CV. Blitzspot dan penentuan strategi untuk mempertahankan konsumen CV. Blitzspot.  Metode Analisis daya saing yang digunakan adalah Model Analisis Berlian Porter dan Metode Pengelompokkan Pelanggan yang digunakan adalah Metode LRFM. Berdasarkan hasil pengujian dan pembahasan yang telah dibuat, maka dapat ditarik kesimpulan bahwa Direktur Utama dapat menganalisis daya saing CV. Blitzspot dengan menggunakan Berlian Porter untuk meningkatkan kualitas layanan terhadap pelanggan CV. Blitzspot.

  9. Exploring best cataloguing rules in the 21st century: Changes from ...

    African Journals Online (AJOL)

    In this digital era, the need to embrace change is inevitable. The authors described fundamental changes that were necessary to move cataloguing practice to the next level. Some of these changes include but not limited to: cataloguing working tools, changes in information resources, vocabulary, main entry points and ...

  10. Earthquake Forecasting Methodology Catalogue - A collection and comparison of the state-of-the-art in earthquake forecasting and prediction methodologies

    Science.gov (United States)

    Schaefer, Andreas; Daniell, James; Wenzel, Friedemann

    2015-04-01

    Earthquake forecasting and prediction has been one of the key struggles of modern geosciences for the last few decades. A large number of approaches for various time periods have been developed for different locations around the world. A categorization and review of more than 20 of new and old methods was undertaken to develop a state-of-the-art catalogue in forecasting algorithms and methodologies. The different methods have been categorised into time-independent, time-dependent and hybrid methods, from which the last group represents methods where additional data than just historical earthquake statistics have been used. It is necessary to categorize in such a way between pure statistical approaches where historical earthquake data represents the only direct data source and also between algorithms which incorporate further information e.g. spatial data of fault distributions or which incorporate physical models like static triggering to indicate future earthquakes. Furthermore, the location of application has been taken into account to identify methods which can be applied e.g. in active tectonic regions like California or in less active continental regions. In general, most of the methods cover well-known high-seismicity regions like Italy, Japan or California. Many more elements have been reviewed, including the application of established theories and methods e.g. for the determination of the completeness magnitude or whether the modified Omori law was used or not. Target temporal scales are identified as well as the publication history. All these different aspects have been reviewed and catalogued to provide an easy-to-use tool for the development of earthquake forecasting algorithms and to get an overview in the state-of-the-art.

  11. Efficacy of pneumococcal nontypable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV in young Latin American children: A double-blind randomized controlled trial.

    Directory of Open Access Journals (Sweden)

    Miguel W Tregnaghi

    2014-06-01

    confirmed AOM, 100% (95% CI: 74.3%, 100% against vaccine serotype IPD, and 65.0% (95% CI: 11.1%, 86.2% against any IPD. Results were consistent between intent-to-treat and per-protocol analyses. Serious adverse events were reported for 21.5% (95% CI: 20.7%, 22.2% and 22.6% (95% CI: 21.9%, 23.4% of PHiD-CV and control recipients, respectively. There were 19 deaths (n = 11,798; 0.16% in the PHiD-CV group and 26 deaths (n = 11,799; 0.22% in the control group. A significant study limitation was the lower than expected number of captured AOM cases.Efficacy was demonstrated against a broad range of pneumococcal diseases commonly encountered in young children in clinical practice.www.ClinicalTrials.gov NCT00466947.

  12. Herpes simplex virus produces larger plaques when assayed on ultraviolet irradiated CV1 cells

    International Nuclear Information System (INIS)

    Coohill, T.P.; Babich, M.A.; Taylor, W.D.; Snipes, W.

    1980-01-01

    Plaque development for either untreated or UV treated irradiated Herpes simplex virus Type 1 was faster when assayed on UV irradiated CV1 cells. This Large Plaque Effect only occurred if a minimum delay of 12h between cell irradiation and viral inoculation was allowed. Shorter delays gave plaques that were smaller than controls (unirradiated virus-unirradiated cells). The effect was maximal for a 48-h delay and remained unchanged for delays as long as 84h. The effect was greatest for cell exposures of 10Jm -2 . (author)

  13. Effect of inoculation and nitrogen top-dressing on yields and fodder value of winter pea cv. Maksimirski ozimi in triticale cv. Clercal mixture

    Directory of Open Access Journals (Sweden)

    Darko Uher

    2006-07-01

    Full Text Available Two year field trials (1999-2001 were aimed to determine the inoculation seed winter pea and nitrogen top-dressing effect on number and active nodules of pea root and also on the green mass and dry matter yield of winter pea cv. Maksimirski ozimi and triticale cv. Clercal mixture. Immediately before sowing the inoculation of pea seeds was done by the indigenous variety of Rhizobium leguminosarum bv. viciae which belongs to the collection of Department of Microbiology at the Faculty of Agriculture University of Zagreb. The highest total nodule number on pea root (134 was determined on the inoculated variant as well as active nodule (120. Average mixture green mass yields were ranging from 20.9 t ha-1 (control up to 30.1 t ha-1 (inoculation + nitrogen top-dressing. Total dry matter yields were ranging from 3.71 t ha-1 (control up to 5.36 t ha-1 (nitrogen top-dressing. Pea crude protein yields in 2001 were ranging from 500 kg ha-1 (nitrogen top-dressing up to 642 kg ha-1 (inoculation and for triticale, those values were from 322 kg ha-1 (control up to 498 kg ha-1 (nitrogen top-dressing. Total mixture crude proteins yields were from 845 kg ha-1 (control up to 998 kg ha-1 (nitrogen top-dressing.

  14. Avaliação da cv. Cabernet Sauvignon para elaboração de vinho tinto

    Directory of Open Access Journals (Sweden)

    Rizzon Luiz Antenor

    2002-01-01

    Full Text Available A uva Cabernet Sauvignon, originária da região de Bordeaux, França, foi introduzida no Brasil em 1921, mas foi somente a partir de 1980 que houve incremento de seu plantio na Serra Gaúcha. É uma cultivar destinada à elaboração de vinho tinto de guarda ou jovem. Devido a sua importância, conduziu-se esse trabalho com o objetivo de determinar as características agronômicas e enológicas da cv. Cabernet Sauvignon para a elaboração de vinho tinto. Para isso, realizaram-se estudos para caracterizar o cacho, o mosto e o vinho tinto nas safras de 1987 a 1992. Os resultados evidenciaram que a cv. Cabernet Sauvignon tem cacho de tamanho médio de 149.3g/L e baga pequena de 1.40g. O mosto possui bom teor de açúcar e acidez titulável de 120meq/L, adequada para a produção de vinho tinto, o qual se caracteriza por apresentar teores elevados de álcoois superiores. Sob o aspecto sensorial, o vinho Cabernet Sauvignon se caracteriza pela cor vermelha relativamente intensa e com reflexos violáceos acentuados; pelo aroma típico que lembra pimentão-verde, que é sua característica varietal; e pelo corpo, estrutura e boa distinguibilidade.

  15. Effects of electromagnetic radiation from 3G mobile phone on heart rate, blood pressure and ECG parameters in rats.

    Science.gov (United States)

    Colak, Cengiz; Parlakpinar, Hakan; Ermis, Necip; Tagluk, Mehmet Emin; Colak, Cemil; Sarihan, Ediz; Dilek, Omer Faruk; Turan, Bahadir; Bakir, Sevtap; Acet, Ahmet

    2012-08-01

    Effects of electromagnetic energy radiated from mobile phones (MPs) on heart is one of the research interests. The current study was designed to investigate the effects of electromagnetic radiation (EMR) from third-generation (3G) MP on the heart rate (HR), blood pressure (BP) and ECG parameters and also to investigate whether exogenous melatonin can exert any protective effect on these parameters. In this study 36 rats were randomized and evenly categorized into 4 groups: group 1 (3G-EMR exposed); group 2 (3G-EMR exposed + melatonin); group 3 (control) and group 4 (control + melatonin). The rats in groups 1 and 2 were exposed to 3G-specific MP's EMR for 20 days (40 min/day; 20 min active (speech position) and 20 min passive (listening position)). Group 2 was also administered with melatonin for 20 days (5 mg/kg daily during the experimental period). ECG signals were recorded from cannulated carotid artery both before and after the experiment, and BP and HR were calculated on 1st, 3rd and 5th min of recordings. ECG signals were processed and statistically evaluated. In our experience, the obtained results did not show significant differences in the BP, HR and ECG parameters among the groups both before and after the experiment. Melatonin, also, did not exhibit any additional effects, neither beneficial nor hazardous, on the heart hemodynamics of rats. Therefore, the strategy (noncontact) of using a 3G MP could be the reason for ineffectiveness; and use of 3G MP, in this perspective, seems to be safer compared to the ones used in close contact with the head. However, further study is needed for standardization of such an assumption.

  16. Instant OpenCV starter

    CERN Document Server

    Dalal, Jayneil

    2013-01-01

    Get to grips with a new technology, understand what it is and what it can do for you, and then get to work with the most important features and tasks.A practical, quick, and hands-on guide for Python developers and hobbyists who want to get started with computer vision with OpenCV.This book is great for developers, hobbyists, and students new to computer vision who are looking to get a good grounding in how to use the OpenCV library. It's assumed that you will have some basic experience in C/C++ programming.

  17. The effect of the gate electrode on the C-V- characteristics of the structure M-TmF3-SiO2-Si

    International Nuclear Information System (INIS)

    Basily, R.R.

    1979-09-01

    The C-V characteristics of the structure M-TmF 3 -SiO 2 -Si, thermally treated at a temperature of 300 0 C for 15 minutes, were investigated. At higher temperatures to about 150 0 C, the hysteresis of the C-V characteristics is completely absent, whereas at room temperature hysteresis depends on the applied voltage and on the material of the gate electrode. The dependence of the flat band voltage shift on the applied voltage, the thickness of SiO 2 layer and the material of the gate electrode were measured. (author)

  18. The Heliospheric Cataloguing, Analysis and Techniques Service (HELCATS) project

    Science.gov (United States)

    Barnes, D.; Harrison, R. A.; Davies, J. A.; Perry, C. H.; Moestl, C.; Rouillard, A.; Bothmer, V.; Rodriguez, L.; Eastwood, J. P.; Kilpua, E.; Gallagher, P.; Odstrcil, D.

    2017-12-01

    Understanding solar wind evolution is fundamental to advancing our knowledge of energy and mass transport in the solar system, whilst also being crucial to space weather and its prediction. The advent of truly wide-angle heliospheric imaging has revolutionised the study of solar wind evolution, by enabling direct and continuous observation of both transient and background components of the solar wind as they propagate from the Sun to 1 AU and beyond. The recently completed, EU-funded FP7 Heliospheric Cataloguing, Analysis and Techniques Service (HELCATS) project (1st May 2014 - 30th April 2017) combined European expertise in heliospheric imaging, built up over the last decade in particular through leadership of the Heliospheric Imager (HI) instruments aboard NASA's STEREO mission, with expertise in solar and coronal imaging as well as the interpretation of in-situ and radio diagnostic measurements of solar wind phenomena. HELCATS involved: (1) the cataloguing of transient (coronal mass ejections) and background (stream/corotating interaction regions) solar wind structures observed by the STEREO/HI instruments, including estimates of their kinematic properties based on a variety of modelling techniques; (2) the verification of these kinematic properties through comparison with solar source observations and in-situ measurements at multiple points throughout the heliosphere; (3) the assessment of the potential for initialising numerical models based on the derived kinematic properties of transient and background solar wind components; and (4) the assessment of the complementarity of radio observations (Type II radio bursts and interplanetary scintillation) in the detection and analysis of heliospheric structure in combination with heliospheric imaging observations. In this presentation, we provide an overview of the HELCATS project emphasising, in particular, the principal achievements and legacy of this unprecedented project.

  19. Integration and magnitude homogenization of the Egyptian earthquake catalogue

    International Nuclear Information System (INIS)

    Hussein, H.M.; Abou Elenean, K.A.; Marzouk, I.A.; Abu El-Nader, E.; Peresan, A.; Korrat, I.M.; Panza, G.F.; El-Gabry, M.N.

    2008-03-01

    The aim of the present work is to compile and update a catalogue of the instrumentally recorded earthquakes in Egypt, with uniform and homogeneous source parameters as required for the analysis of seismicity and seismic hazard assessment. This in turn requires a detailed analysis and comparison of the properties of different available sources, including the distribution of events with time, the magnitude completeness and the scaling relations between different kinds of magnitude reported by different agencies. The observational data cover the time interval 1900- 2004 and an area between 22--33.5 deg N and 25--3 6 deg. E. The linear regressions between various magnitude types have been evaluated for different magnitude ranges. Using the best linear relationship determined for each available pair of magnitudes, as well as those identified between the magnitudes and the seismic moment, we convert the different magnitude types into moment magnitudes M W , through a multi-step conversion process. Analysis of the catalogue completeness, based on the MW thus estimated, allows us to identify two different time intervals with homogeneous properties. The first one (1900- 1984) appears to be complete for M W ≥ 4.5, while the second one (1985-2004) can be considered complete for magnitudes M W ≥ 3. (author)

  20. Plasminogen activator inhibitor-1 5G/5G genotype is associated with early spontaneous recanalization of the infarct-related artery in patients presenting with acute ST-elevation myocardial infarction.

    Science.gov (United States)

    Cagliyan, Caglar E; Yuregir, Ozge O; Balli, Mehmet; Tekin, Kamuran; Akilli, Rabia E; Bozdogan, Sevcan T; Turkmen, Serdar; Deniz, Ali; Baykan, Oytun A; Aslan, Huseyin; Cayli, Murat

    2013-05-01

    We aimed to examine the association between plasminogen activator inhibitor-1 (PAI-1) genetic polymorphism and early spontaneous recanalization in patients presenting with acute ST-elevation myocardial infarction. Patients admitted to our emergency department with ST-elevation myocardial infarction in the first 6 h of symptom onset were included. An immediate primary percutaneous coronary intervention was performed. Patients were grouped according to the initial patency of the infarct-related artery (IRA) as follows: total occlusion (TO) group [Thrombolysis in Myocardial Infarction (TIMI) 0-1 flow in the IRA], partial recanalization group (TIMI 2 flow in the IRA), and complete recanalization (CR) group (TIMI 3 flow in the IRA). PAI-1 4G/5G polymorphism was detected using the real-time PCR method. There were 107 patients in the TO group, 30 patients in the partial recanalization group, and 45 patients in the CR group. When we evaluated degrees of patency according to the PAI-1 genotype, TO of the IRA was the highest in patients with the PAI 4G/4G genotype (PAI-1 4G/4G: 66.7%, PAI-1 4G/5G: 65.9%, PAI-1 5G/5G: 40.4%) and CR of the IRA was the highest in patients with the PAI 5G/5G genotype (PAI-1 5G/5G: 38.5%, PAI-1 4G/5G: 19.8%, PAI-1 4G/4G: 17.9%). The distribution of genotypes in different degrees of patency of IRA was statistically significant (P=0.029). In logistic regression analysis, the PAI-1 5G/5G genotype was associated independently with the spontaneous CR of the IRA (odds ratio: 2.875, 95% confidence interval [1.059-7.086], P=0.038). Patients with the PAI-1 5G/5G genotype seem to be luckier than others in terms of early spontaneous recanalization of the IRA. Further prospective studies with large patient populations are required for more precise results.

  1. Combined effect of organic manure and potassium on growth and yield of onion cv. BARI piaz-I

    Directory of Open Access Journals (Sweden)

    H.K. Barman

    2013-06-01

    Full Text Available An experiment was conducted to find out the combined effect of cowdung and potassium on the growth and yield of onion cv. BARI piaz-I at Horticulture Farm, Bangladesh Agricultural University, Mymensingh during the period from December 2010 to March 2011. The experiment was laid out in a randomized complete block design with three replications. The two factors experiment had four levels of cowdung, viz., 0, 5, 10 and 20 tons ha-1 and four levels of potassium, viz. 0, 50, 150 and 250 kg K ha-1. Doses of cowdung and potassium showed significant variation in respect of all the parameters studied. The combination of 10 tons cowdung and 250 kg K ha-1 gave the tallest plant (46.60 cm, the highest number of leaves plant-1 (6.40, the highest length of bulb (3.27 cm, the highest diameter of bulb (4.83 cm, individual weight of bulb (51.23 g, dry matter content (12.66% and yield of bulb ha-1 (12.83 tons; whereas the control treatment gave the shortest plant (38.15 cm, lowest number of leaves plant-1 (5.68, diameter of bulb (3.41, individual weight of bulb (35.65g and gave lowest bulb yield ha-1 (9.16 tons.

  2. Catalogue of the Coreidae in the Rijksmuseum van Natuurlijke Historie : Part I. Corizinae, Alydinae

    NARCIS (Netherlands)

    Blöte, H.C.

    1934-01-01

    As a result of my further work on the reordening of the collection of bugs in the Leiden Museum I am giving now a catalogue of the Coreidae in the Museum, which will appear in some parts, as the group is rather large. Again I was enabled to visit the British Museum (Natural History), and I will

  3. Roma-BZCAT: a multifrequency catalogue of blazars

    Science.gov (United States)

    Massaro, E.; Giommi, P.; Leto, C.; Marchegiani, P.; Maselli, A.; Perri, M.; Piranomonte, S.; Sclavi, S.

    2009-02-01

    We present a new catalogue of blazars based on multifrequency surveys and on an extensive review of the literature. Blazars are classified as BL Lacertae objects, as flat spectrum radio quasars or as blazars of uncertain/transitional type. Each object is identified by a root name, coded as BZB, BZQ and BZU for these three subclasses respectively, and by its coordinates. This catalogue is being built as a tool useful for the identification of the extragalactic sources that will be detected by present and future experiments for X and gamma-ray astronomy, like Swift, AGILE, Fermi-GLAST and Simbol-X. An electronic version is available from the ASI Science Data Center web site at http://www.asdc.asi.it/bzcat.

  4. Continuous micro-earthquake catalogue of the central Southern Alps, New Zealand

    Science.gov (United States)

    Michailos, Konstantinos; Townend, John; Savage, Martha; Chamberlain, Calum

    2017-04-01

    The Alpine Fault is one of the most prominent tectonic features in the South Island, New Zealand, and is inferred to be late in its seismic cycle of M 8 earthquakes based on paleoseismological evidence. Despite this, the Alpine Fault displays low levels of contemporary seismic activity, with little documented on-fault seismicity. This low magnitude seismicity, often below the completeness level of the GeoNet national seismic catalogue, may inform us of changes in fault character along-strike and might be used for rupture simulations and hazard planning. Thus, compiling a micro-earthquake catalogue for the Southern Alps prior to an expected major earthquake is of great interest. Areas of low seismic activity, like the central part of the Alpine Fault, require data recorded over a long duration to reveal temporal and spatial seismicity patterns and provide a better understanding for the processes controlling seismogenesis. The continuity and density of the Southern Alps Microearthquake Borehole Array (SAMBA; deployed in late 2008) allows us to study seismicity in the Southern Alps over a more extended time period than has ever been done previously. Furthermore, by using data from other temporary networks (e.g. WIZARD, ALFA08, DFDP-10) we are able to extend the region covered. To generate a spatially and temporally continuous catalogue of seismicity in New Zealand's central Southern Alps, we used automatic detection and phase-picking methods. We used an automatic phase-picking method for both P- and S- wave arrivals (kPick; Rawles and Thurber, 2015). Using almost 8 years of seismic data we calculated about 9,000 preliminary earthquake. The seismicity is clustered and scattered and a previously observed seismic gap between the Wanganui and Whataroa rivers is also identified.

  5. Association of the TYMS 3G/3G genotype with poor response and GGH 354GG genotype with the bone marrow toxicity of the methotrexate in RA patients.

    Science.gov (United States)

    Jekic, Biljana; Lukovic, Ljiljana; Bunjevacki, Vera; Milic, Vera; Novakovic, Ivana; Damnjanovic, Tatjana; Milasin, Jelena; Popovic, Branka; Maksimovic, Nela; Damjanov, Nemanja; Radunovic, Goran; Kovacevic, Ljiljana; Krajinovic, Maja

    2013-03-01

    Gamma-glutamyl hydrolase (GGH), cyclin D1 (CCND1) and thymidylate synthase (TS) genes encode enzymes that are involved in methotrexate (MTX) action. In a group of 184 RA patients treated with MTX, we have investigated whether selected polymorphisms in these genes modulate MTX efficacy and/or have impact on adverse drug effects (ADEs). The efficacy of the MTX therapy has been estimated using the disease activity score in 28 joints (DAS28-ESR) based on EULAR criteria and relative DAS28 values (rDAS28). All adverse drug events were recorded. Patients were genotyped for selected polymorphisms of the GGH (-354 G > T and 452 C > T), CCND1 (870 A > G) and TYMS (variable number of tandem repeats, VNTR, and G to C substitution of triple repeat, 3R allele) gene. Association studies have been performed between obtained genotypes and the efficacy and toxicity of MTX. According to the EULAR response criteria, 146 RA patients (79.3 %) were classified as responders (good/moderate response) and 38 (20.7 %) as non-responders (poor response). Higher frequency of the TYMS 3 G/3 G genotype has been found among non-responders as compared to individuals with remaining genotypes (p = 0.02). ADEs were recorded in 53 patients. Among those patients eight experienced bone marrow toxicity, all of them carried GGH -354GG genotype (p = 0.003). No other significant association were observed. The 3 G/3 G genotype of the TYMS gene may indicate predisposition of poor response to MTX and GG genotype of GGH -354 T > G polymorphism may have high predictive value for myelosuppression in RA patients.

  6. CINDU catalogue of numerical neutron data available from the IAEA Nuclear Data Unit

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1968-05-15

    This catalogue is the index to DASTAR, the DAta STorage And Retrieval System of the IAEA Nuclear Data Unit. It is written in a slightly modified CINDA format and should be read with the help of the introduction to CINDA, Tables of abbreviations for references and laboratories mentioned in this issue are given on the verso of the front cover. The catalogue serves as a reference to all the experimental and calculated numerical data which have been entered into DASTAR, and each set of data i s indexed with a DASTAR-number, e.g. DASTAR-00434. The bibliographic references for each experiment are blocked together with the relevant DASTAR-number entry. All of the indexed data are available to anyone on request. Data should be ordered by their DASTAR-number. This issue of CINDU is distributed to data centres, members of the International Nuclear Data Committee, correspondents to the IAEA Nuclear Data Unit, and others who have expressed their interest. Entries which have been added or changed since the issue of CINDU-6 are marked with an asterisk following the entry date.

  7. Antidiabetic and anticancer activities of Mangifera indica cv. Okrong leaves

    Science.gov (United States)

    Ganogpichayagrai, Aunyachulee; Palanuvej, Chanida; Ruangrungsi, Nijsiri

    2017-01-01

    Diabetes and cancer are a major global public health problem. Plant-derived agents with undesirable side-effects were required. This study aimed to evaluate antidiabetic and anticancer activities of the ethanolic leaf extract of Mangifera indica cv. Okrong and its active phytochemical compound, mangiferin. Antidiabetic activities against yeast α-glucosidase and rat intestinal α-glucosidase were determined using 1 mM of p-nitro phenyl-α-D-glucopyranoside as substrate. Inhibitory activity against porcine pancreatic α-amylase was performed using 1 mM of 2-chloro-4 nitrophenol-α-D-maltotroside-3 as substrate. Nitrophenol product was spectrophotometrically measured at 405 nm. Anticancer activity was evaluated against five human cancer cell lines compared to two human normal cell lines using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Mango leaf extract and mangiferin exhibited dose-dependent inhibition against yeast α-glucosidase with the IC50 of 0.0503 and 0.5813 mg/ml, respectively, against rat α-glucosidase with the IC50 of 1.4528 and 0.4333 mg/ml, respectively, compared to acarbose with the IC50 of 11.9285 and 0.4493 mg/ml, respectively. For anticancer activity, mango leaf extract, at ≥200 μg/ml showed cytotoxic potential against all tested cancer cell lines. In conclusion, mango leaf possessed antidiabetic and anticancer potential in vitro. PMID:28217550

  8. The Vaporization of B2O3(l) to B2O3(g) and B2O2(g)

    Science.gov (United States)

    Jacobson, Nathan S.; Myers, Dwight L.

    2011-01-01

    The vaporization of B2O3 in a reducing environment leads to formation of both B2O3(g) and B2O2(g). While formation of B2O3(g) is well understood, many questions about the formation of B2O2(g) remain. Previous studies using B(s) + B2O3(l) have led to inconsistent thermodynamic data. In this study, it was found that after heating, B(s) and B2O3(l) appear to separate and variations in contact area likely led to the inconsistent vapor pressures of B2O2(g). To circumvent this problem, an activity of boron is fixed with a two-phase mixture of FeB and Fe2B. Both second and third law enthalpies of formation were measured for B2O2(g) and B2O3(g). From these the enthalpies of formation at 298.15 K are calculated to be -479.9 +/- 41.5 kJ/mol for B2O2(g) and -833.4 +/- 13.1 kJ/mol for B2O3(g). Ab initio calculations to determine the enthalpies of formation of B2O2(g) and B2O3(g) were conducted using the W1BD composite method and show good agreement with the experimental values.

  9. Long-Chain Acetylenic Ketones from the Micronesian Sponge Haliclona sp. Importance of the 1-yn-3-ol Group for Antitumor Activity

    Directory of Open Access Journals (Sweden)

    Guang-Xiong Zhou

    2003-11-01

    Full Text Available Abstract: Two new long-chain C33 polyacetylenic compounds, halicynones A and B were isolated from the marine sponge Haliclona sp. along with known analogs. The known compound pellynol A possessing a 1-yn-3-ol terminus, exhibited strong antitumor activity against the human colon tumor cell line HCT-116 (IC50 0.026 μg/mL, however, the corresponding 1-yn-3-one, halicynone A, was inactive, which suggests an important role for the terminal 1-yn-3-ol functional group in mediating cytotoxic activity.

  10. Effect of Radiofrequency Radiation Emitted from 2G and 3G Cell Phone on Developing Liver of Chick Embryo - A Comparative Study.

    Science.gov (United States)

    D'Silva, Mary Hydrina; Swer, Rijied Thompson; Anbalagan, J; Rajesh, Bhargavan

    2017-07-01

    The increasing scientific evidence of various health hazards on exposure of Radiofrequency Radiation (RFR) emitted from both the cell phones and base stations have caused significant media attention and public discussion in recent years. The mechanism of interaction of RF fields with developing tissues of children and fetuses may be different from that of adults due to their smaller physical size and variation in tissue electromagnetic properties. The present study may provide an insight into the basic mechanisms by which RF fields interact with developing tissues in an embryo. To evaluate the possible tissue and DNA damage in developing liver of chick embryo following chronic exposure to Ultra-High Frequency/Radiofrequency Radiation (UHF/RFR) emitted from 2G and 3G cell phone. Fertilized chick embryos were incubated in four groups. Group A-experimental group exposed to 2G radiation (60 eggs), Group B- experimental group exposed to 3G radiation (60 eggs), Group C- sham exposed control group (60 eggs) and Group D- control group (48 eggs). On completion of scheduled duration, the embryos were collected and processed for routine histological studies to check structural changes in liver. The nuclear diameter and karyorrhexis changes of hepatocytes were analysed using oculometer and square reticule respectively. The liver procured from one batch of eggs from all the four groups was subjected to alkaline comet assay technique to assess DNA damage. The results were compared using one-way ANOVA test. In our study, the exposure of developing chick embryos to 2G and 3G cell phone radiations caused structural changes in liver in the form of dilated sinusoidal spaces with haemorrhage, increased vacuolations in cytoplasm, increased nuclear diameter and karyorrhexis and significantly increased DNA damage. The chronic exposure of chick embryo liver to RFR emitted from 2G and 3G cell phone resulted in various structural changes and DNA damage. The changes were more pronounced in 3

  11. In brown adipocytes, adrenergically induced β{sub 1}-/β{sub 3}-(G{sub s})-, α{sub 2}-(G{sub i})- and α{sub 1}-(G{sub q})-signalling to Erk1/2 activation is not mediated via EGF receptor transactivation

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Yanling; Fälting, Johanna M.; Mattsson, Charlotte L.; Holmström, Therése E.; Nedergaard, Jan, E-mail: jan@metabol.su.se

    2013-10-15

    Brown adipose tissue is unusual in that the neurotransmitter norepinephrine influences cell destiny in ways generally associated with effects of classical growth factors: regulation of cell proliferation, of apoptosis, and progression of differentiation. The norepinephrine effects are mediated through G-protein-coupled receptors; further mediation of such stimulation to e.g. Erk1/2 activation is in cell biology in general accepted to occur through transactivation of the EGF receptor (by external or internal pathways). We have examined here the significance of such transactivation in brown adipocytes. Stimulation of mature brown adipocytes with cirazoline (α{sub 1}-adrenoceptor coupled via G{sub q}), clonidine (α{sub 2} via G{sub i}) or CL316243 (β{sub 3} via G{sub s}) or via β{sub 1}-receptors significantly activated Erk1/2. Pretreatment with the EGF receptor kinase inhibitor AG1478 had, remarkably, no significant effect on Erk1/2 activation induced by any of these adrenergic agonists (although it fully abolished EGF-induced Erk1/2 activation), demonstrating absence of EGF receptor-mediated transactivation. Results with brown preadipocytes (cells in more proliferative states) were not qualitatively different. Joint stimulation of all adrenoceptors with norepinephrine did not result in synergism on Erk1/2 activation. AG1478 action on EGF-stimulated Erk1/2 phosphorylation showed a sharp concentration–response relationship (IC{sub 50} 0.3 µM); a minor apparent effect of AG1478 on norepinephrine-stimulated Erk1/2 phosphorylation showed nonspecific kinetics, implying caution in interpretation of partial effects of AG1478 as reported in other systems. Transactivation of the EGF receptor is clearly not a universal prerequisite for coupling of G-protein coupled receptors to Erk1/2 signalling cascades. - Highlights: • In brown adipocytes, norepinephrine regulates proliferation, apoptosis, differentiation. • EGF receptor transactivation is supposed to mediate GPCR

  12. CERES BiDirectional Scans (BDS) data in HDF (CER_BDS_Aqua-FM3_Edition1)

    Science.gov (United States)

    Wielicki, Bruce A. (Principal Investigator)

    Each BiDirectional Scans (BDS) data product contains twenty-four hours of Level-1b data for each CERES scanner instrument mounted on each spacecraft. The BDS includes samples taken in normal and short Earth scan elevation profiles in both fixed and rotating azimuth scan modes (including space, internal calibration, and solar calibration views). The BDS contains Level-0 raw (unconverted) science and instrument data as well as the geolocated converted science and instrument data. The BDS contains additional data not found in the Level-0 input file, including converted satellite position and velocity data, celestial data, converted digital status data, and parameters used in the radiance count conversion equations. The following CERES BDS data sets are currently available: CER_BDS_TRMM-PFM_Edition1 CER_BDS_Terra-FM1_Edition1 CER_BDS_Terra-FM2_Edition1 CER_BDS_Terra-FM1_Edition2 CER_BDS_Terra-FM2_Edition2 CER_BDS_Aqua-FM3_Edition1 CER_BDS_Aqua-FM4_Edition1 CER_BDS_Aqua-FM3_Edition2 CER_BDS_Aqua-FM4_Edition2 CER_BDS_Aqua-FM3_Edition1-CV CER_BDS_Aqua-FM4_Edition1-CV CER_BDS_Terra-FM1_Edition1-CV CER_BDS_Terra-FM2_Edition1-CV. [Location=GLOBAL] [Temporal_Coverage: Start_Date=1997-12-27; Stop_Date=2005-11-02] [Spatial_Coverage: Southernmost_Latitude=-90; Northernmost_Latitude=90; Westernmost_Longitude=-180; Easternmost_Longitude=180] [Data_Resolution: Temporal_Resolution=1 day; Temporal_Resolution_Range=Daily - < Weekly].

  13. Characterisation of a haemagglutinin from Hokkaido red bean (Phaseolus vulgaris cv. Hokkaido red bean).

    Science.gov (United States)

    Wong, Jack H; Wan, Chung T; Ng, Tzi B

    2010-01-15

    A haemagglutinin was purified from Japanese Hokkaido red beans (Phaseolus vulgaris cv. Hokkaido red bean) with a procedure that included three chromatographic media. Haemagglutinating activity was adsorbed on DEAE cellulose, Affi-gel blue gel and Mono S. The pure haemagglutinin was a homodimer and each subunit was around 30 kDa in molecular mass. The haemagglutinating activity of this agglutinin could not be inhibited by a variety of simple sugars at 200 mmol L(-1) concentration including alpha-L-fucose, D(+)-galactose, D(+)-glucose, D(+)-glucosamine, D(-)galactosamine, galacturonic acid, (+)-lactose, D(+)-melibose, L(-)-mannose, D(+)-mannose, D-mannosamine, D(+)-raffinose, L-rhamnose, (+)-xylose and galacturonic acid. The haemagglutinating activity was fully retained at pH 4-11 and at 0-80 degrees C, but was completely lost at extreme pH values (0-2 and 13-14) and at very high temperatures (90 degrees C and 100 degrees C). The haemagglutinin exhibited a weak mitogenic activity toward mouse splenocytes, a stronger anti-proliferative activity than Con A toward HepG2 (human hepatoma) cells and inhibited >80% of HIV-1 reverse transcriptase inhibitory activity at 3.3 micromol L(-1). It was devoid of anti-fungal activity. Hokkaido red bean haemagglutinin possesses a potent anti-proliferative effect on HepG2 cells. Copyright (c) 2009 Society of Chemical Industry.

  14. Dicty_cDB: Contig-U05312-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 246 ) PDUts1124F05 Porcine testis cDNA library I Sus sc... 48 0.32 1 ( CT631096 ) Danio rerio EST, clone ZF_mu... 46 1.2 1 ( CV877151 ) PDUts1160G12 Porcine testis cDNA library I Sus sc... 46 1.2 1 ( CT729188 ) Danio rerio EST, clone ZF_mu... 44 4.9 1 ( CV865498 ) PDUts1018G06 Porcine testis cDNA library I Sus sc... 44 4.9 1 ( CT735187 ) Danio rerio EST, clone ZF_mu...774433 ) McClintock41_B07.ab1 Homarus EST library project ... 54 0.005 1 ( AU269391 ) Dictyostelium discoideum vegetati...1 3'. 46 1.2 1 ( CK415565 ) AUF_IpPit_32_p21 Pituitary cDNA library Ictalurus...

  15. European wind turbine catalogue

    International Nuclear Information System (INIS)

    1994-01-01

    The THERMIE European Community programme is designed to promote the greater use of European technology and this catalogue contributes to the fulfillment of this aim by dissemination of information on 50 wind turbines from 30 manufacturers. These turbines are produced in Europe and are commercially available. The manufacturers presented produce and sell grid-connected turbines which have been officially approved in countries where this approval is acquired, however some of the wind turbines included in the catalogue have not been regarded as fully commercially available at the time of going to print. The entries, which are illustrated by colour photographs, give company profiles, concept descriptions, measured power curves, prices, and information on design and dimension, safety systems, stage of development, special characteristics, annual energy production, and noise pollution. Lists are given of wind turbine manufacturers and agents and of consultants and developers in the wind energy sector. Exchange rates used in the conversion of the prices of wind turbines are also given. Information can be found on the OPET network (organizations recognised by the European Commission as an Organization for the Promotion of Energy Technologies (OPET)). An article describes the development of the wind power industry during the last 10-15 years and another article on certification aims to give an overview of the most well-known and acknowledged type approvals currently issued in Europe. (AB)

  16. Catalogue of tide gauges in the Pacific

    National Research Council Canada - National Science Library

    Ridgway, N. M

    1984-01-01

    Although this catalogue is primarily intended to provide a list of sources for tidal data which can be used in postevent studies of tsunamis, it may also be useful in other branches of oceanographic...

  17. Semaphorin 3G Provides a Repulsive Guidance Cue to Lymphatic Endothelial Cells via Neuropilin-2/PlexinD1.

    Science.gov (United States)

    Liu, Xinyi; Uemura, Akiyoshi; Fukushima, Yoko; Yoshida, Yutaka; Hirashima, Masanori

    2016-11-22

    The vertebrate circulatory system is composed of closely related blood and lymphatic vessels. It has been shown that lymphatic vascular patterning is regulated by blood vessels during development, but its molecular mechanisms have not been fully elucidated. Here, we show that the artery-derived ligand semaphorin 3G (Sema3G) and the endothelial cell receptor PlexinD1 play a role in lymphatic vascular patterning. In mouse embryonic back skin, genetic inactivation of Sema3G or PlexinD1 results in abnormal artery-lymph alignment and reduced lymphatic vascular branching. Conditional ablation in mice demonstrates that PlexinD1 is primarily required in lymphatic endothelial cells (LECs). In vitro analyses show that Sema3G binds to neuropilin-2 (Nrp2), which forms a receptor complex with PlexinD1. Sema3G induces cell collapse in an Nrp2/PlexinD1-dependent manner. Our findings shed light on a molecular mechanism by which LECs are distributed away from arteries and form a branching network during lymphatic vascular development. Copyright © 2016 The Author(s). Published by Elsevier Inc. All rights reserved.

  18. Differences in outcomes between GOLD groups in patients with COPD in the TIOSPIR® trial

    DEFF Research Database (Denmark)

    Dusser, Daniel; Wise, Robert A; Dahl, Ronald

    2016-01-01

    BACKGROUND: The aim of this study was to evaluate whether Global Initiative for Chronic Obstructive Lung Disease (GOLD) classification could predict mortality risk factors and whether baseline treatment intensity would relate to mortality within each group, using data from TIOSPIR(®), the largest...... randomized clinical trial in COPD performed to date. METHODS: A total of 17,135 patients from TIOSPIR(®) were pooled and grouped by GOLD grading (A-D) according to baseline Medical Research Council breathlessness score, exacerbation history, and spirometry. All-cause mortality and adjudicated cardiovascular...... (CV) and respiratory mortality were assessed. RESULTS: Of the 16,326 patients classified, 1,248 died on treatment. Group B patients received proportionally more CV treatment at baseline. CV mortality risk, but not all-cause mortality risk, was significantly higher in Group B than Group C patients (CV...

  19. Dicty_cDB: Contig-U16278-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available Ridge pineapple sweet orange entire ... 172 9e-48 3 ( CV715589 ) UCRCS08_0005P18_f Parent Washington Navel O...cte... 165 6e-44 3 ( DN619374 ) UCRCS11_03N09_r Parent Washington Navel Orange Sc... 168 6e-44 2 ( DR908461 ...08013E01SK PhyRootSw1 Citrus sinensis cDNA clone... 168 6e-44 2 ( DN617852 ) UCRCS11_01M10_r Parent Washingt...abr00225 Antheraea assama fifth instar larval br... 190 7e-44 1 ( CX074876 ) UCRCS08_41B06_g Parent Washingt... ( CV717911 ) UCRCS08_0009L22_r Parent Washington Navel Orange ... 168 7e-44 2 ( CV717910 ) UCRCS08_0009L22_f Parent

  20. Estimating the fraction of progeny virions that must incorporate APOBEC3G for suppression of productive HIV-1 infection

    International Nuclear Information System (INIS)

    Thangavelu, Pulari U.; Gupta, Vipul; Dixit, Narendra M.

    2014-01-01

    The contest between the host factor APOBEC3G (A3G) and the HIV-1 protein Vif presents an attractive target of intervention. The extent to which the A3G–Vif interaction must be suppressed to tilt the balance in favor of A3G remains unknown. We employed stochastic simulations and mathematical modeling of the within-host dynamics and evolution of HIV-1 to estimate the fraction of progeny virions that must incorporate A3G to render productive infection unsustainable. Using three different approaches, we found consistently that a transition from sustained infection to suppression of productive infection occurred when the latter fraction exceeded ∼0.8. The transition was triggered by A3G-induced hypermutations that led to premature stop codons compromising viral production and was consistent with driving the basic reproductive number, R 0 , below unity. The fraction identified may serve as a quantitative guideline for strategies targeting the A3G–Vif axis. - Highlights: • We perform simulations and mathematical modeling of the role of APOBEC3G in suppressing HIV-1 infection. • In three distinct ways, we estimate that when over 80% of progeny virions carry APOBEC3G, productive HIV-1 infection would be suppressed. • Our estimate of this critical fraction presents quantitative guidelines for strategies targeting the APOBEC3G–Vif axis

  1. The prevalence of PAI-1 4G/5G gene variant in Serbian population

    Directory of Open Access Journals (Sweden)

    Đorđević Valentina

    2013-01-01

    Full Text Available Introduction: Plasminogen activator inhibitor 1 (PAI-1 has a major role in inhibition of firinolysis and normal haemostasis. The presence of the PAI-1 4G/4G genotype leads to increased expression of PAI-1. High blood level of PAI-1 is associated with many diseases such as thrombosis, cerebral insult, myocardial infarction, pregnancy loss, preeclampsia, insulin resistance, type 2 diabetes, breast cancer and asthma. In this study, the prevalence of PAI-1 4G/5G gene variant was determined in healthy subjects from Serbian population. Methods: The study was carried out in a group of 210 healthy subjects (105 women and 105 men. The presence of PAI-1 4G/5G gene variant was detected by PCR-RFLP analysis. Results: The prevalence of PAI-1 4G/4G genotype was 34.76% and it was increased compared to PAI-1 5G/5G genotype (19.05%. The most frequent was PAI-1 4G/5G genotype (46.19%. Allelic frequency for 4G allele was higher (0.58 compared to 5G allele (0.42. Conclusions: The prevalence of PAI-1 4G/5G gene variant in Serbian population is similar to the neighboring populations. Results of this study represent the first data for Serbian population. This study could be useful for further research where the role of PAI-1 4G/5G gene variant will be assessed in the pathogenesis of many diseases.

  2. Planck 2013 results. XXXII. The updated Planck catalogue of Sunyaev-Zeldovich sources

    DEFF Research Database (Denmark)

    Ade, P. A. R.; Aghanim, N.; Armitage-Caplan, C.

    2015-01-01

    We update the all-sky Planck catalogue of 1227 clusters and cluster candidates (PSZ1) published in March 2013, derived from detections of the Sunyaev-Zeldovich (SZ) effect using the first 15.5 months of Planck satellite observations. As an addendum, we deliver an updated version of the PSZ1 catal...

  3. EIF3G is associated with narcolepsy across ethnicities

    DEFF Research Database (Denmark)

    Holm, Anja; Lin, Ling; Faraco, Juliette

    2015-01-01

    conserved in mammals and zebrafish containing PPAN, EIF3G and DNMT1 (DNA methyltransferase 1). As mutations in DNMT1 cause a rare dominant form of narcolepsy in association with deafness, cerebellar ataxia and dementia, we questioned whether the association with P2RY11 in sporadic narcolepsy could...... be secondary to linkage disequilibrium with DNMT1. Based on genome-wide association data from two cohorts of European and Chinese ancestry, we found that the narcolepsy association signal drops sharply between P2RY11/EIF3G and DNMT1, suggesting that the association with narcolepsy does not extend into the DNMT......1 gene region. Interestingly, using transethnic mapping, we identified a novel single-nucleotide polymorphism rs3826784 (c.596-260A>G) in the EIF3G gene also associated with narcolepsy. The disease-associated allele increases EIF3G mRNA expression. EIF3G is located in the narcolepsy risk locus...

  4. Dicty_cDB: Contig-U02520-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ) KBrH001K21F KBrH, Brassica rapa HindIII BAC libra... 46 3.3 1 ( CT538104 ) A BAC library has been constructed from culti...1 ( DR026249 ) Osmo00116 F. cylindrus osmotic stress library Fra... 46 3.3 1 ( DN805411 ) 76947238 Sea Urchi...( CV793140 ) c-030216-1w_E04.abd cDNA library of Tamarix andro... 46 3.3 1 ( CV672849 ) RET7SJ_07D06.T7 Schistosoma japonicum re...012 2 ( CK416159 ) AUF_IpPit_34_o05 Pituitary cDNA library Ictalurus... 54 0.013 1 ( FE840166 ) CCAG48972.g1...99 ) NF075H11EC1F1095 Elicited cell culture Medicago t... 48 0.20 2 ( BF647354 ) NF075A06EC1F1040 Elicited cell culture Medic

  5. Synthesis and antitumoral activity of novel 3-(2-substituted-1,3,4-oxadiazol-5-yl) and 3-(5-substituted-1,2,4-triazol-3-yl) beta-carboline derivatives.

    Science.gov (United States)

    Formagio, Anelise S Nazari; Tonin, Lilian T Düsman; Foglio, Mary Ann; Madjarof, Christiana; de Carvalho, João Ernesto; da Costa, Willian Ferreira; Cardoso, Flávia P; Sarragiotto, Maria Helena

    2008-11-15

    Several novel 1-substituted-phenyl beta-carbolines bearing the 2-substituted-1,3,4-oxadiazol-5-yl and 5-substituted-1,2,4-triazol-3-yl groups at C-3 were synthesized and evaluated for their in vitro anticancer activity. The assay results pointed thirteen compounds with growth inhibition effect (GI(50)<100 microM) for all eight different types of human cancer cell lines tested. The beta-carbolines 7a and 7h, bearing the 3-(2-metylthio-1,3,4-oxadiazol-5-yl) group, displayed high selectivity and potent anticancer activity against ovarian cell line with GI(50) values lying in the nanomolar concentration range (GI(50)=10 nM for both compounds). The 1-(N,N-dimethylaminophenyl)-3-(5-thioxo-1,2,4-triazol-3-yl) beta-carboline (8g) was the most active compound, showing particular effectiveness on lung (GI(50)=0.06 microM), ovarian and renal cell lines. The potent anticancer activity presented for synthesized compounds 7a, 7h, and 8g, together with their easiness of synthesis, makes these compounds promising anticancer agents.

  6. Global fibrinolytic activity, PAI-1 level, and 4G/5G polymorphism in Thai children with arterial ischemic stroke.

    Science.gov (United States)

    Natesirinilkul, Rungrote; Sasanakul, Werasak; Chuansumrit, Ampaiwan; Kadegasem, Praguywan; Visudtibhan, Anannit; Wongwerawattanakoon, Pakawan; Sirachainan, Nongnuch

    2014-01-01

    Prolonged euglobulin clot lysis time (ECLT) and increased level of plasminogen activator inhibitor-1 (PAI-1) were reported to be risk factors of arterial ischemic stroke (AIS) by some studies; however, these findings were not supported by other studies. The objective of this study was to determine the association of ECLT, PAI-1 level, and polymorphisms of 4G and 5G of PAI-1 gene to the development of AIS in Thai children. This study included patients aged 1-18 years old. Diagnosis of AIS was confirmed by imaging study. The control group was age- and sex-matched healthy subjects. Demographic data were recorded, and blood was tested for ECLT, PAI-1 level, lipid profiles, fasting blood sugar (FBS), and 4G and 5G polymorphisms of PAI-1 gene. There were 70 subjects participating in this study, consisting of 30 patients and 40 controls. Demographic data, lipid profiles, and FBS were similar between the 2 groups. Furthermore, ECLT and PAI-1 level did not differ between patient and control groups; however, both showed significant correlation (r = .352, P = .006). The 4G/5G polymorphism was the most common genotype in both patient and control groups (69.0% vs. 80.0%). However, 4G and 5G polymorphisms of PAI-1 gene did not correlate with PAI-1 level in this study (P = .797). The PAI-1 level and 4G/5G polymorphism may not be a risk factor of AIS in this population. It was also found that the 4G/5G polymorphism was the most common PAI-1 genotype in this study. Copyright © 2014 National Stroke Association. Published by Elsevier Inc. All rights reserved.

  7. Synthesis and characterization of supramolecule self-assembly polyami-doamine (PAMAM G1-G1 NH2, CO2H end group Megamer

    Directory of Open Access Journals (Sweden)

    Omid Louie

    2014-10-01

    Full Text Available Supramolecule self-assembly polyamidoamine (PAMAM dendrimer refers to the chemical sys-tems made up of a discrete number of assembled molecular subunits or components. These strat-egies involve the covalent assembly of hierarchical components reactive monomers, branch cells or dendrons around atomic or molecular cores according to divergent/convergent dendritic branching principles, systematic filling of space around a core with shells (layers of branch cells. The polydispersity index (PDI for the supramolecule megamer are pretty closed to one, are in agreement with the Poisson probability distribution. Polyamidoamine (PAMAM den-drimer G1-G1 that it was PAMAM Megamer NH2, COOH end groupsynthesized and character-ized by FT-IR, 1H NMR, 13C NMRspectra and GelPermeation Chromatography (GPC.

  8. Efeito de substratos na aclimatização de mudas micropropagadas de abacaxizeiro cv. Pérola Acclimatization of micropropagated pineapple plants cv. "Pérola": substrata effect

    Directory of Open Access Journals (Sweden)

    Maria Aparecida Moreira

    2006-10-01

    Full Text Available Objetivou-se com este trabalho verificar o efeito da matéria orgânica como componente de substratos para mudas micropropagadas de abacaxizeiro cv. Pérola em fase de aclimatização. Mudas micropropagadas de abacaxizeiro cv. Pérola, selecionadas de acordo com o peso (aproximadamente 2 g, foram plantadas em bandejas de isopor de 72 células de 120 cm³ contendo proporções de substratos com terra, esterco bovino, Plantmax e matéria orgânica. O delineamento estatístico utilizado foi o inteiramente casualizado com 4 repetições e 3 plantas por parcela. As avaliações foram feitas 90 dias após o plantio, quando se avaliou: altura da planta, comprimento de raiz, peso de matéria fresca de raiz e parte aérea, peso de matéria seca de raiz e parte aérea e número de folhas. Com os resultados obtidos, conclui-se que a matéria orgânica tem efeito significativo no desenvolvimento das mudas. Com o substrato contendo terra, esterco e Plantmax foi obtido o melhor desenvolvimento das raízes e parte aérea.The objective of this work was to evaluate the effect of the organic matter as component of substrata for micropropagated plants of pineapple cv. Pérola in the acclimatization phase. Micropropagated plants were selected according to the weight (approximately 2g and planted in trays with 72 cels of 120 cm³, containing substrata made of soil, bovine manure, Plantmax and organic matter at different proportions. At 90 days after planting, the following parameters were evaluated: height of the plant, root length, weight of fresh matter of root and aerial part, dry matter weight of root and aerial part and number of leaves. The obtained results allowed to conclude that the organic matter has significant effect on the development of the seedlings. The best results for the development of the roots and aerial part were obtained with substratum containing soil, manure and Plantmax.

  9. CV equipment responsibilities

    CERN Document Server

    Pirollet, B

    2008-01-01

    This document describes the limits of the responsibilities of the TS/CV for fire fighting equipment at the LHC. The various interfaces, providers and users of the water supply systems and clean water raising systems are described.

  10. Evaluation of Bio-Rad D-100 HbA1c analyzer against Tosoh G8 and Menarini HA-8180V

    Directory of Open Access Journals (Sweden)

    José María Maesa

    2016-08-01

    Full Text Available Objectives: To evaluate the Bio-Rad D-100®, an HPLC analyzer for glycated hemoglobin (HbA1c determination, and to compare its performance with the Menarini HA-8180V® and Sysmex G8®. Methods: Method comparison was performed according to Clinical and Laboratory Standards Institute (CLSI EP9-A2 guidelines. We selected 100 samples from the routine laboratory workload and analyzed them in duplicate with the three analyzers. The imprecision study was performed according to CLSI EP5-A2 guidelines for both inter-assay and intra-assay variability. Bias was assessed with external quality control material. To establish linearity, CLSI EP6-A protocol was followed. Results: Method comparison (95% confidence intervals in parentheses: D-100 vs G8: Passing-Bablok regression; y=0.973(0.963–0.983×−0.07(−0.07−0.069; r=0.9989. Bland-Altman mean difference: −0.229%HbA1c (−0.256: −0.202; Relative bias plot: D-100/G8 vs D100-G8 mean ratio=0.971(0.967−0.975. D-100 vs HA-8180V: Passing-Bablok regression; y=0.944(0.932–0.958×−0.078(0.024−0.173; r=0.9989. Bland-Altman mean difference: −0.363%HbA1c (−0.401: −0.325; Relative bias plot D-100/HA-8180V vs D100-HA-8180V mean ratio=0.955(0.952−0.958. Inter-assay coefficient of variation (CV: 0.81%. Intra-assay CV: 1.04% (low level, and 0.78% (high level. Bias against target value=2.332%. Linearity: r2=0.998 in the concentration range 4.4−13.9%HbA1c. Carry-over: 0.0024%. Conclusions: The Bio-Rad D-100 shows good correlation with G8 and HA-8180V. There is a small proportional systematic difference (2.7% and 5.6%, respectively in both comparisons. Inter and intra-assay CVs are both lower than the lowest CV obtained in studies performed with D-100 and other instruments. Keywords: Glycated hemoglobin, High performance liquid chromatography, Analyzer, Intra-assay variability, Inter-assay variability

  11. Analysis of the presence of pseudoscience in the catalogues of public libraries in Spain

    Directory of Open Access Journals (Sweden)

    Sergi Cortiñas-Rovira

    2018-02-01

    Full Text Available This paper examines the presence of books regarding instances of pseudoscience as their main topic in catalogues of public libraries in Spain, as well as the opinion of such works about pseudoscience. A database is created to analyse both absolute and relative amounts of those works in all Spanish catalogues. The numbers show a small, yet worrying percentage of 0.15% titles concerning several pseudosciences and prove astrology as the most abundant instance in libraries. The study also explains the menace of homeopathy, as the works about this pseudotherapy outnumber those regarding chemotherapy in a 1/20 ratio.

  12. Studies on Colombian Cryptogams IV. A catalogue of the Hepaticae of Colombia

    NARCIS (Netherlands)

    Gradstein, S.R.; Hekking, W.H.A.

    1979-01-01

    □ The main purpose of this catalogue is to provide a complete listing of the species of liverworts hitherto known from Colombia and to summarize our present knowledge of species distribution within the country. It was prepared parallel to a catalogue of the mosses (Musci), which is being published

  13. Planck 2015 results: XXVII. The second Planck catalogue of Sunyaev-Zeldovich sources

    DEFF Research Database (Denmark)

    Ade, P. A R; Aghanim, N.; Arnaud, M.

    2016-01-01

    We present the all-sky Planck catalogue of Sunyaev-Zeldovich (SZ) sources detected from the 29 month full-mission data. The catalogue (PSZ2) is the largest SZ-selected sample of galaxy clusters yet produced and the deepest systematic all-sky surveyof galaxy clusters. It contains 1653 detections, ...

  14. Modern Special Collections Cataloguing: A University of London Case Study

    OpenAIRE

    Attar, Karen

    2013-01-01

    Recent years have seen a growing emphasis on modern special collections (in themselves no new phenomenon), with a dichotomy between guidance for detailed cataloguing in Descriptive Cataloging of Rare Materials (Books) (DCRM(B), 2007) and the value of clearing cataloguing backlogs expeditiously. This article describes the De la Mare Family Archive of Walter de la Mare's Printed Oeuvre at Senate House Library, University of London, as an example of a modern author collections in an institutiona...

  15. The inhibition of activated hepatic stellate cells proliferation by arctigenin through G0/G1 phase cell cycle arrest: persistent p27(Kip1) induction by interfering with PI3K/Akt/FOXO3a signaling pathway.

    Science.gov (United States)

    Li, Ao; Wang, Jun; Wu, Mingjun; Zhang, Xiaoxun; Zhang, Hongzhi

    2015-01-15

    Proliferation of hepatic stellate cells (HSCs) is vital for the development of fibrosis during liver injury. In this study, we describe that arctigenin (ATG), a major bioactive component of Fructus Arctii, exhibited selective cytotoxic activity via inhibiting platelet-derived growth factor-BB (PDGF-BB)-activated HSCs proliferation and arrested cell cycle at G0/G1 phase, which could not be observed in normal human hepatocytes in vitro. The cyclin-dependent kinase (CDK) 4/6 activities could be strongly inhibited by ATG through down-regulation of cyclin D1 and CDK4/6 expression in early G1 phase arrest. In the ATG-treated HSCs, the expression level of p27(Kip1) and the formation of CDK2-p27(Kip1) complex were also increased. p27(Kip1) silencing significantly attenuated the effect of ATG, including cell cycle arrest and suppression of proliferation in activated HSCs. We also found that ATG suppressed PDGF-BB-induced phosphorylation of Akt and its downstream transcription factor Forkhead box O 3a (FOXO3a), decreased binding of FOXO3a to 14-3-3 protein, and stimulated nuclear translocation of FOXO3a in activated HSCs. Furthermore, knockdown of FOXO3a expression by FOXO3a siRNA attenuated ATG-induced up-regulation of p27(Kip1) in activated HSCs. All the above findings suggested that ATG could increase the levels of p27(Kip1) protein through inhibition of Akt and improvement of FOXO3a activity, in turn inhibited the CDK2 kinase activity, and eventually caused an overall inhibition of HSCs proliferation. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Cytometry of chromatin bound Mcm6 and PCNA identifies two states in G1 that are separated functionally by the G1 restriction point1

    Directory of Open Access Journals (Sweden)

    Jacobberger James W

    2010-04-01

    Full Text Available Abstract Background Cytometric measurements of DNA content and chromatin-bound Mcm2 have demonstrated bimodal patterns of expression in G1. These patterns, the replication licensing function of Mcm proteins, and a correlation between Mcm loading and cell cycle commitment for cells re-entering the cell cycle, led us to test the idea that cells expressing a defined high level of chromatin-bound Mcm6 in G1 are committed - i.e., past the G1 restriction point. We developed a cell-based assay for tightly-bound PCNA (PCNA* and Mcm6 (Mcm6*, DNA content, and a mitotic marker to clearly define G1, S, G2, and M phases of the cell cycle. hTERT-BJ1, hTERT-RPE-1, and Molt4 cells were extracted with Triton X-100 followed by methanol fixation, stained with antibodies and DAPI, then measured by cytometry. Results Bivariate analysis of cytometric data demonstrated complex patterns with distinct clustering for all combinations of the 4 variables. In G1, cells clustered in two groups characterized by low and high Mcm6* expression. Serum starvation and release experiments showed that residence in the high group was in late G1, just prior to S phase. Kinetic experiments, employing serum withdrawal, and stathmokinetic analysis with aphidicolin, mimosine or nocodazole demonstrated that cells with high levels of Mcm6* cycled with the committed phases of the cell cycle (S, G2, and M. Conclusions A multivariate assay for Mcm6*, PCNA*, DNA content, and a mitotic marker provides analysis capable of estimating the fraction of pre and post-restriction point G1 cells and supports the idea that there are at least two states in G1 defined by levels of chromatin bound Mcm proteins.

  17. Reduction of the LVEF measured with gSPECT after 1-3 hours after physical exercise in CAD

    International Nuclear Information System (INIS)

    Cholewinski, W.; Stefaniak, B.; Poniatowicz-Frasunek, E.; Tarkowska, A.

    2004-01-01

    Aim: It has been shown that exercise may lead to the myocardial stunning with reduction of LVEF, persisting for some time despite recovery of perfusion. The aim of this study was to check whether the post-stress decrease of LVEF lasts as long as 3h after exercise. Patients, methods: The study was performed in 46 patients with CAD and in 10 normals (NMS). All patients underwent myocardial gSPECT after 99m Tc-tetrofosmin injection at rest and during stress with 2-day protocol. SPECT was started 1h after tracer injection at rest (R) and twice: 1h (S1) and 3hs(S3) after injection at stress. LVEF was calculated by the method of Germano et al. Results: All LVEF values were significantly lower in CAD patients than in the control group. In NMS mean LVEF was at rest similar to those obtained 1h and 3h after stress injection (59.0 ± 4.1, 60.0 ± 5.9, 58.0 ± 4.6, respectively; p > 0.05). A post-exercise decrease of LVEF was observed in 2 normal patients both at S1 and at S3. In CAD group LVEF values were lower at S1 than at R (50.8 ± 13.6 versus 49.3 ± 12.8; p < 0.05) and at S3 were lower than at S1 (49.3 ± 12.8 versus 46.0 ± 12.2; p < 0.001). A significant decrease of LVEF was found in 18/46 patients 1h post stress and in 36/46 3h post stress. In patients with reversible perfusion decrease, a significant correlation was found between post-exercise deterioration of perfusion and post-exercise LVEF reduction both at S1 (r = 0.744; p < 0.02) and at S3 (r = 0.734; p < 0.02). Stress induced decrease in LVEF correlated also with severity of perfusion abnormalities. Conclusions: In the majority of patients with CAD physical stress applied for diagnostic purposes results in an impairment of the LV function. A decrease of the LVEF is observed 1h after exercise, but it increases in frequency and grows stronger during the next 2h.The post-stress LVEF reduction is related to the severity of perfusion abnormalities. Patients with CAD who underwent diagnostic stress test should

  18. Efficacy of Pneumococcal Nontypable Haemophilus influenzae Protein D Conjugate Vaccine (PHiD-CV) in Young Latin American Children: A Double-Blind Randomized Controlled Trial

    Science.gov (United States)

    Tregnaghi, Miguel W.; Sáez-Llorens, Xavier; López, Pio; Abate, Hector; Smith, Enrique; Pósleman, Adriana; Calvo, Arlene; Wong, Digna; Cortes-Barbosa, Carlos; Ceballos, Ana; Tregnaghi, Marcelo; Sierra, Alexandra; Rodriguez, Mirna; Troitiño, Marisol; Carabajal, Carlos; Falaschi, Andrea; Leandro, Ana; Castrejón, Maria Mercedes; Lepetic, Alejandro; Lommel, Patricia; Hausdorff, William P.; Borys, Dorota; Guiñazú, Javier Ruiz; Ortega-Barría, Eduardo; Yarzábal, Juan P.; Schuerman, Lode

    2014-01-01

    , 67.1% (95% CI: 17.0%, 86.9%) against vaccine serotype clinically confirmed AOM, 100% (95% CI: 74.3%, 100%) against vaccine serotype IPD, and 65.0% (95% CI: 11.1%, 86.2%) against any IPD. Results were consistent between intent-to-treat and per-protocol analyses. Serious adverse events were reported for 21.5% (95% CI: 20.7%, 22.2%) and 22.6% (95% CI: 21.9%, 23.4%) of PHiD-CV and control recipients, respectively. There were 19 deaths (n = 11,798; 0.16%) in the PHiD-CV group and 26 deaths (n = 11,799; 0.22%) in the control group. A significant study limitation was the lower than expected number of captured AOM cases. Conclusions Efficacy was demonstrated against a broad range of pneumococcal diseases commonly encountered in young children in clinical practice. Trial registration www.ClinicalTrials.gov NCT00466947 Please see later in the article for the Editors' Summary PMID:24892763

  19. Effects of electromagnetic radiation produced by 3G mobile phones on rat brains: magnetic resonance spectroscopy, biochemical, and histopathological evaluation.

    Science.gov (United States)

    Dogan, M; Turtay, M G; Oguzturk, H; Samdanci, E; Turkoz, Y; Tasdemir, S; Alkan, A; Bakir, S

    2012-06-01

    The effects of electromagnetic radiation (EMR) produced by a third-generation (3G) mobile phone (MP) on rat brain tissues were investigated in terms of magnetic resonance spectroscopy (MRS), biochemistry, and histopathological evaluations. The rats were randomly assigned to two groups: Group 1 is composed of 3G-EMR-exposed rats (n = 9) and Group 2 is the control group (n = 9). The first group was subjected to EMR for 20 days. The control group was not exposed to EMR. Choline (Cho), creatinin (Cr), and N-acetylaspartate (NAA) levels were evaluated by MRS. Catalase (CAT) and glutathione peroxidase (GSH-Px) enzyme activities were measured by spectrophotometric method. Histopathological analyses were carried out to evaluate apoptosis in the brain tissues of both groups. In MRS, NAA/Cr, Cho/Cr, and NAA/Cho ratios were not significantly different between Groups 1 and 2. Neither the oxidative stress parameters, CAT and GSH-Px, nor the number of apoptotic cells were significantly different between Groups 1 and 2. Usage of short-term 3G MP does not seem to have a harmful effect on rat brain tissue.

  20. VizieR Online Data Catalog: Catalogue of Stellar Spectral Classifications (Skiff, 2010)

    Science.gov (United States)

    Skiff, B. A.

    2009-02-01

    Morgan & Abt 'MKA' paper (1972AJ.....77...35M) not appearing in the two later lists are added. Keenan made continual adjustments to the standards lists up to the time of his death. Thus the late-type standards comprise those marked as high-weight standards in the 1989 Perkins catalogue (1989ApJS...71..245K = III/150); the revised S-type standards in collaboration with Boeshaar (1980ApJS...43..379K); plus the carbon standards and class IIIb 'clump giants' in collaboration with Barnbaum (1996ApJS..105..419B and 1999ApJ...518..859K). In addition, I have made use of the final types by Keenan up to January 2000 shown at the Ohio State Web site (http://www.astronomy.ohio-state.edu/MKCool), accessed in autumn 2003. Though the present file contains all the stars in these lists, only those marked as standards are flagged as such. Garrison's list of MK 'anchor points' might also be consulted in this regard (1994mpyp.conf....3G, and http://www.astro.utoronto.ca/~garrison/mkstds.html). The catalogue includes for the first time results from many large-scale objective-prism spectral surveys done at Case, Stockholm, Crimea, Abastumani, and elsewhere. The stars in these surveys were usually identified only on charts or by other indirect means, and have been overlooked heretofore because of the difficulty in recovering the stars. More complete results from these separate publications, including notes and identifications, have been made available to the CDS, and are kept at the Lowell Observatory ftp area (ftp://ftp.lowell.edu/pub/bas/starcats). Not all of these stars are present in SIMBAD. As a 'living catalogue', an attempt will be made to keep up with current literature, and to extend the indexing of citations back in time. (2 data files).

  1. Evaluation of modified atmosphere bag and sulphur dioxide concentrations applied on highbush blueberries fruit (Vaccinium corymbosum L.) cv. Emerald

    OpenAIRE

    Rodríguez, Mario; Wyss, Anddy; Hormazábal, Nelson

    2015-01-01

    Aiming to evaluate techniques for modified atmosphere and application of sulphur anhydride upon parameters of quality of postharvest on blueberry fruit (Vaccinium corymbosum L.) cv. Emerald, an experiment of six treatments was conducted, given by the combination of two factors, modified atmosphere (with and without) and different concentrations of sulphur dioxide (generated by 0, 1 and 2 g of sodium metabisulphite) during 7, 14, 21 and 28 days at 0 °C. The dose of 2 g of modified atmosphere s...

  2. Biofilm formation of beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis isolates and its association with emm polymorphism.

    Science.gov (United States)

    Ma, Jui-Shan; Chen, Sin-Yu; Lo, Hsueh-Hsia

    2017-11-01

    Biofilm formation has been well known as a determinant of bacterial virulence. Group G Streptococcus dysgalactiae subspecies equisimilis (SDSE), a relevant pathogen with increasing medical importance, was evaluated for the biofilm-forming potential. Microtiter plate assay was used to assess the most feasible medium for group G SDSE to form a biofilm. Among 246 SDSE isolates examined, 46.7%, 43.5%, 33.3%, and 26.4% of isolates showed moderate or strong biofilm-forming abilities using tryptic soy broth (TSB), brain heart infusion broth (BHI), Todd-Hewitt broth (THB), and C medium with 30 mM glucose (CMG), respectively. The addition of glucose significantly increased the biofilm-forming ability of group G SDSE. FCT (fibronectin-collagen-T-antigen) typing of SDSE was first undertaken and 11 FCT types were found. Positive associations of stG10.0 or negative associations of stG245.0, stG840.0, and stG6.1 with biofilm-forming ability of SDSE were, respectively, found. This was the first investigation demonstrating biofilm-forming potential in clinical group G SDSE isolates; also, some significant associations of biofilm-forming ability with certain emm types were presented. © 2017 APMIS. Published by John Wiley & Sons Ltd.

  3. Brightest group galaxies - II: the relative contribution of BGGs to the total baryon content of groups at z < 1.3

    Science.gov (United States)

    Gozaliasl, Ghassem; Finoguenov, Alexis; Khosroshahi, Habib G.; Henriques, Bruno M. B.; Tanaka, Masayuki; Ilbert, Olivier; Wuyts, Stijn; McCracken, Henry J.; Montanari, Francesco

    2018-04-01

    We performed a detailed study of the evolution of the star formation rate (SFR) and stellar mass of the brightest group galaxies (BGGs) and their relative contribution to the total baryon budget within R200 (f^{BGG}_{b,200}). The sample comprises 407 BGGs selected from X-ray groups (M200 = 1012.8-1014 M⊙) out to z ˜ 1.3 identified in the Cosmic Evolution Survey (COSMOS), XMM Large-Scale Structure survey (XMM-LSS), and the All-Wavelength Extended Groth strip International Survey (AEGIS) fields. We find that BGGs constitute two distinct populations of quiescent and star-forming galaxies and their mean SFR is ˜2 dex higher than the median SFR at z 2 dex. We take into account the halo mass growth of groups in selecting the sample of BGGs and find that the mean (median) stellar mass of BGGs has grown by 0.3 dex since z = 1.3 to the present day. We show that up to ˜ 45 per cent of the stellar mass growth in a star-forming BGG can be due to its star formation activity. With respect to f^{BGG}_{b,200}, we find it to increase with decreasing redshift by ˜0.35 dex, while decreasing with halo mass in a redshift-dependent manner. We show that the slope of the relation between f^{BGG}_{b,200} and halo mass increases negatively with decreasing redshift. This trend is driven by an insufficient star formation in BGGs, compared to the halo growth rate. We separately show the BGGs with the 20 per cent highest f^{BGG}_{b,200} are generally non-star-forming galaxies and grow in mass by processes not related to star formation (e.g. dry mergers and tidal striping). We present the M⋆-Mh and M⋆/Mh-Mh relations and compare them with semi-analytic model predictions and a number of results from the literature. We quantify the intrinsic scatter in stellar mass of BGGs at fixed halo mass (σ _{log M_{\\star}}) and find that σ _{{log }M_{\\star}} increases from 0.3 dex at z ˜ 0.2-0.5 dex at z ˜ 1.0 due to the bimodal distribution of stellar mass.

  4. Tendencies in the application of the concept of catalogue marketing in Republic of Serbia and the world

    Directory of Open Access Journals (Sweden)

    Zelić Darko

    2010-01-01

    Full Text Available Catalogue marketing is one of the direct marketing channels. This concept implies making a lot of strategic and tactical decisions that determine catalogue's market success. Catalogue sales is most developed in USA (where it originated and in Western Europe. In Serbia, catalogue marketing is applied just in last few years, since big foreign catalog companies started their business in this region. Here, catalogue marketing is at a lower level of development than in the developed countries, and it comprises a minor part of total trade turnover. The positive thing is that now there are laws that regulates this area, which is encouraging for its development. More and more companies in Serbia are presenting and selling its product range through Internet catalogs. The survey, whose results are briefly presented in this article, showed that consumers in Serbia shop less by print catalogues than consumers in developed countries, and that the partition of those who buy through e-catalogues is increasing. With the increase in standard of living, and overcoming the crisis, there is a chance for catalogue marketing to become much more important concept among consumers and companies in Serbia.

  5. Evaluation of faba beans ( Vicia faba cv. Fiord) and sweet lupins ...

    African Journals Online (AJOL)

    Evaluation of faba beans ( Vicia faba cv. Fiord) and sweet lupins ( Lupizus albus cv. Kiev) as protein sources for ... P igsi n the metabolisrna ndN balance trial consurned5 % less( P < 0.01)o 1'thel upind ietc omparedto the fabab eand iet (l 370 vs. | 440 gld).N o significandt ift'erenceisn the digestiblee nergy( DE) contenta nd ...

  6. ICP OES and CV AAS in determination of mercury in an unusual fatal case of long-term exposure to elemental mercury in a teenager.

    Science.gov (United States)

    Lech, Teresa

    2014-04-01

    In this work, a case of deliberate self-poisoning is presented. A 14-year-old girl suddenly died during one of the several hospitalizations. Abdominal computer tomography showed a large number of metallic particles in the large intestine. Analysis of blood and internal organs for mercury and other toxic metals carried out by inductively coupled plasma optical emission spectrometry (ICP OES) revealed high concentrations of mercury in kidneys and liver (64,200 and 2470ng/g, respectively), less in stomach (90ng/g), and none in blood. Using cold vapor-atomic absorption spectrometry (CV AAS), high levels of mercury were confirmed in all examined materials, including blood (87ng/g), and additionally in hair. The results of analysis obtained by two techniques revealed that the exposure to mercury was considerable (some time later, it was stated that the mercury originated from thermometers that had been broken over the course of about 1 year, because of Münchausen syndrome). CV AAS is a more sensitive technique, particularly for blood samples (negative results using ICP OES), and tissue samples - with LOQ: 0.63ng/g of Hg (CV AAS) vis-à-vis 70ng/g of Hg (ICP OES). However, ICP OES may be used as a screening technique for autopsy material in acute poisoning by a heavy metal, even one as volatile as mercury. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  7. The compiled catalogue of galaxies in machine-readable form and its statistical investigation

    International Nuclear Information System (INIS)

    Kogoshvili, N.G.

    1982-01-01

    The compilation of a machine-readable catalogue of relatively bright galaxies was undertaken in Abastumani Astrophysical Observatory in order to facilitate the statistical analysis of a large observational material on galaxies from the Palomar Sky Survey. In compiling the catalogue of galaxies the following problems were considered: the collection of existing information for each galaxy; a critical approach to data aimed at the selection of the most important features of the galaxies; the recording of data in computer-readable form; and the permanent updating of the catalogue. (Auth.)

  8. The British Film Catalogue: 1895-1970.

    Science.gov (United States)

    Gifford, Denis

    This reference book catalogues nearly every commercial film produced in Britain for public entertainment from 1895 to 1970. The entries are listed chronologically by year and month. Each entry is limited to a single film and contains a cross index code number, exhibition date, main title, length, color system, production company, distribution…

  9. The mineral chemistry and origin of inclusion matrix and meteorite matrix in the Allende CV3 chondrite

    International Nuclear Information System (INIS)

    Kornacki, A.S.; Wood, J.A.; Harvard Univ., Cambridge, MA

    1984-01-01

    The two textural varieties of olivine-rich Allende inclusions consist primarily of a porous, fine-grained mafic constituent that differs from the opaque meteorite matrix of CV3 chondrites by being relatively depleted in sulfides, metal grains, and carbonaceous material. Olivine is the most abundant mineral in Allende inclusion matrix; clinopyroxene, nepheline, sodalite, and Ti-Al-pyroxene occur in lesser amounts. Olivine in unrimmed olivine aggregates is ferrous and has a narrow compositional range. Olivine in rimmed olivine aggregates is, on average, more magnesian, with a wider compositional range. Olivine grains in the granular rims of Type 1B inclusions are zoned, with magnesian cores and ferrous rinds. Ferrous olivines in both varieties of inclusions commonly contain significant amounts of Al 2 O 3 , CaO and TiO 2 , refractory elements that probably occur in submicroscopic inclusions of Ca, Al, Ti-rich glass. Defocussed beam analyses of Allende matrix materials are discussed. (author)

  10. Prospective Study of Surgical Treatment of Acromegaly: Effects on Ghrelin, Weight, Adiposity, and Markers of CV Risk

    Science.gov (United States)

    Reyes-Vidal, Carlos; Fernandez, Jean Carlos; Bruce, Jeffrey N.; Crisman, Celina; Conwell, Irene M.; Kostadinov, Jane; Geer, Eliza B.; Post, Kalmon D.

    2014-01-01

    Context: Although epidemiological studies have found that GH and IGF-1 normalization reduce the excess mortality of active acromegaly to expected rates, cross-sectional data report some cardiovascular (CV) risk markers to be less favorable in remission than active acromegaly. Objective: The objective of the study was to test the hypothesis that remission of acromegaly after surgical therapy increases weight and adiposity and some CV risk markers and these changes are paralleled by a rise in ghrelin. Design: Forty-two adults with untreated, active acromegaly were studied prospectively. Changes in outcome measures from before to after surgery were assessed in 26 subjects achieving remission (normal IGF-1) and 16 with persistent active acromegaly (elevated IGF-1) after surgery. Setting: The study was conducted at tertiary referral centers for pituitary tumors. Main Outcome Measures: Endocrine, metabolic, and CV risk parameters, anthropometrics, and body composition by dual-energy X-ray absorptiometry were measured. Results: Remission increased total ghrelin, body weight, waist circumference, C-reactive protein, homocysteine, high-density lipoprotein, and leptin and reduced systolic blood pressure, homeostasis model assessment score, triglycerides, and lipoprotein (a) by 6 months and for 32 ± 4 months after surgery. The ghrelin rise correlated with the fall in the levels of GH, IGF-1, and insulin and insulin resistance. Weight, waist circumference, and ghrelin did not increase significantly in the persistent active acromegaly group. Total body fat, trunk fat, and perentage total body fat increased by 1 year after surgery in 15 remission subjects: the increase in body fat correlated with the rise in total ghrelin. Conclusions: Although most markers of CV risk improve with acromegaly remission after surgery, some markers and adiposity increase and are paralleled by a rise in total ghrelin, suggesting that these changes may be related. Understanding the mechanisms and

  11. Digitisation of Lace Catalogues and Patterns at the Idrija Municipal Museum and Lace School

    Directory of Open Access Journals (Sweden)

    Mirjam Gnezda Bogataj

    2013-09-01

    more complicated as they are perforated, folded, rolled, however, it is one of the future challenges of lace pattern digitisation. In 2009 six sales catalogues of lace patterns from the early 20th century kept by the Idrija Municipal Museum were digitised. In 2011 they were followed by 1.050 patterns of the Zorka Rupnik collection from the second half of 20th century. Thus the originals have been preservedand safely stored in the museum while users can access and browse them with the help of computersin the museum. At the same time a part of the collection of the Lace School was digitised. The school requested to keep the scale factor of the original patterns (scale 1:1 and that necessary metadata were provided. On one hand the originals were preserved while on the other hand the collection was made accessible to children and teachers in dislocated departments of the school. Some questions regarding digitisation of lace patterns are still open:  1. Due to the capacity of the printer, reproduction is limited to A3 paper format.   2. Access to the patterns is limited by copyright rules.   3. How to reproduce – to convert digital objects to material ones (specific requirements for colour persistence, paper hardness.   4. Long-term storage and preservation of digitised materials.

  12. A facile synthesis of Li_2Fe_1_/_3Mn_1_/_3Ni_1_/_3SiO_4/C composites as cathode materials for lithium-ion batteries

    International Nuclear Information System (INIS)

    Yang, Rong; Wang, Liqing; Deng, Kunfa; Lv, Mengni; Xu, Yunhua

    2016-01-01

    The novel Li_2Fe_1_/_3Mn_1_/_3Ni_1_/_3SiO_4/C has been successfully synthesized by a feasible solution process in ternary system. The spherical carbon-coated composites are obtained using a heat treatment in the presence of sucrose. X-ray diffraction (XRD) diffractogram displays that the Li_2Fe_1_/_3Mn_1_/_3Ni_1_/_3SiO_4/C crystallized in an orthorhombic structure with a space group of Pmn21. The energy-dispersive X-ray spectroscopy mappings indicate that Fe, Mn and Ni elements are distributed homogenously in Li_2Fe_1_/_3Mn_1_/_3Ni_1_/_3SiO_4/C nano-spherical particle with size less than 50 nm. The lithium storage capacity and cycling performance of the Li_2Fe_1_/_3Mn_1_/_3Ni_1_/_3SiO_4/C presents good results when tested as cathode materials in lithium cells at room temperature. It delivers an initial discharge capacity of 181.4 mAh g"−"1 and a discharge capacity of 172.9 mAh g"−"1 after 20 cycles at 0.1C in the voltage range of 1.5–4.6V. Furthermore, it also exhibits an excellent rate capability with a capacity under different current densities of about 144.0 mAh g"−"1 (0.2 C), 117.9 mAh g"−"1 (0.5 C), 106.1 mAh g"−"1 (1 C), respectively and a good capacity cycling maintenance of 153.7 mAh g"−"1 after 60 cycles. Above results indicate that the spherical Li_2Fe_1_/_3Mn_1_/_3Ni_1_/_3SiO_4/C becomes a very promising candidate for cathode material in lithium-ion batteries. - Highlights: • Li_2Fe_1_/_3Mn_1_/_3Ni_1_/_3SiO_4/C was obtained by solution process in a ternary system. • The material was pure phase ternary solid solution with tetrahedral morphology. • The spherical particle size was less than 50 nm with graphitized carbon coating. • The nanocomposite revealed high discharge capacity and excellent rate capability.

  13. CURRENT TRENDS IN CATALOGUING AND THE CHALLENGES ...

    African Journals Online (AJOL)

    resources collected by libraries, results in rich metadata that can be used for many .... in creating timely and high quality records, cataloguers need to develop a ... is a professional function for which there is no substitutes for the human begin.

  14. [Regularity of Clinical Application of Lianquan (CV 23) in Chinese Ancient Times According to Literature of Traditional Chinese Medicine].

    Science.gov (United States)

    Deng, Mei-Jun; Liu, Chun-Yan; Xie, Yu; Zhu, Jie-Bin; Xu, Zhen-Hua

    2018-03-25

    To summarize the regularity of application of Lianquan (CV 23) in clinical practice in Chinese ancient times through analysis of ancient traditional Chinese medical (TCM) literature. A total of 60 books involving CV 23 from the 1 156 ancient TCM books listed in the fifth edition of Encyclopedia of Traditional Chinese Medicine were collected by using CV 23 as the main keyword and "Sheben" "Benchi", and "Jieben" (the other names of CV 23 in TCM)as the supplementary keywords and analyzed systematically. A database was then constructed from the collected data, including the related types of disorders or symptoms, acupoint recipes, and methods of needling and moxibustion, contraindications, etc. A total of 196 articles related to the application of CV 23 from 60 ancient classical books were collected in accordance with the inclusive criteria. Among them, 155 articles are referred to the indications of CV 23, 35 to types of disorders such as asthma, cough, tongue swelling with difficulty in speaking, protracted tongue, acute contraction of tongue root, vomiting, spasm syndrome, stroke, aphtha, problems of mouth and teeth, throat problems, etc. of the internal medicine, surgery, pediatrics, and five-sense organs; 64 items are referred to the application of single CV 23, 91 to CV 23-included recipes containing 111 adjunct acupoints, and 78 to stimulation of CV 23 with acupuncture needle, moxibustion, pricking blood, and fire needle. Moreover, of the 111 adjunct acupoints, the most commonly used are Shaoshang (LU 11), Tiantu (CV 22), Hegu (LI 4), Yuye (EX-HN 13), Zhongchong (PC 9), etc. Lianquan (CV 23) is mainly used for glossopharyngeal problems chiefly by syndrome-meridian differentiation. The supplement of complementary acupoints or five-shu points in combination with CV 23 has a synergistic effect. Moxibustion (3 moxa- cones in general) is often employed, and the needling depth is usually about 7.5 mm. The common contraindication of CV 23 is severe tongue swelling.

  15. Propagación in vitro de Heliconia bihai (L. cv. Lobster Salmón a partir de meristemos florales In vitro propagation of Heliconia bihai (L. cv. Lobster Salmón from flowering buds

    Directory of Open Access Journals (Sweden)

    Marta Leonor Marulanda-ángel

    2011-04-01

    Full Text Available Se desarrolló un protocolo de propagación in vitro a partir de meristemos florales para Heliconia bihai cv. Lobster Salmón. Para el efecto se establecieron 250 yemas florales en diferentes tiempos utilizando NaClO al 1% durante 20 min. El medio de establecimiento Murashige y Skoog con mejores resultados fue BAP (2 mg/lt, AIA (1 mg/lt y 0.1 g/lt de L-cisteína. La mayor produccion de brotes en multiplicación se obtuvo con 6 mg/lt de BAP y con un subcultivo posterior en medio con 2 mg/lt de BAP y 0.5 mg/lt de AIA, alcanzando una tasa de multiplicación de tres nuevas yemas. El enraizamiento de las plántulas in vitro se logró con 1.3 mg/lt de AIA. La aclimatación en vivero fue 92% de supervivencia. Se realizó un análisis de varianza (Anova y un test de Tukey para las variables evaluadas las cuales mostraron diferencias estadísticas en cada fase. La propagación in vitro de heliconias a partir de yemas florales requiere mayor tiempo en la fase de establecimiento y multiplicación, no obstante permite mayores porcentajes de supervivencia y una menor contaminación, ofreciendo material de siembra de diferentes especies de esta planta de interés comercial.A protocol for in vitro propagation of Heliconia bihai cv. Lobster Salmón was developed using flowering buds as initial explants. 250 flowering buds were established in different assays with NaClO at 1% during 20 minutes. The establishment in Murashige & Skoog's medium with BAP (2mg/L, AIA (1 mg/L and L-cystein (0.1 g/L showed the best results. Shoot multiplication was obtained with BAP (6 mg/L with a subsequent subculture in a medium with BAP (2 mg/L and AIA (0.5 mg/L, reaching multiplication rates of 3.0 new shoots. Rooting was achieved with AIA 1.3 mg/L. The survival rate during greenhouse acclimatization was 92%. Analysis of variance (ANOVA and Turkey's test were realized for each of the variables evaluated that showed statistical differences in all stages. The in vitro propagation of

  16. 4G/5G and A-844G Polymorphisms of Plasminogen Activator Inhibitor-1 Associated with Glioblastoma in Iran--a Case-Control Study.

    Science.gov (United States)

    Pooyan, Honari; Ahmad, Ebrahimi; Azadeh, Rakhshan

    2015-01-01

    Glioblastoma is a highly aggressive and malignant brain tumor. Risk factors are largely unknown however, although several biomarkers have been identified which may support development, angiogenesis and invasion of tumor cells. One of these biomarkers is PAI-1. 4G/5G and A-844G are two common polymorphisms in the gene promotor of PAI 1 that may be related to high transcription and expression of this gene. Studies have shown that the prevalence of the 4G and 844G allele is significantly higher in patients with some cancers and genetic disorders. We here assessed the association of 4G/5G and A-844G polymorphisms with glioblastoma cancer risk in Iranians in a case-control study. All 71 patients with clinically confirmed and 140 volunteers with no history and symptoms of glioblastoma as control group were screened for 4G/5G and A-844G polymorphisms of PAI-1, using ARMS-PCR. Genotype and allele frequencies of case and control groups were analyzed using the DeFinetti program. Our results showed significant associations between 4G/5G (p=0.01824) and A-844G (p=0.02012) polymorphisms of the PAI-1 gene with glioblastoma cancer risk in our Iranian population. The results of this study supporting an association of the PAI-1 4G/5G (p=0.01824) and A-844G (p=0.02012) polymorphisms with increasing glioblastoma cancer risk in Iranian patients.

  17. CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer.

    Science.gov (United States)

    Stefansson, Olafur Andri; Hermanowicz, Stefan; van der Horst, Jasper; Hilmarsdottir, Holmfridur; Staszczak, Zuzanna; Jonasson, Jon Gunnlaugur; Tryggvadottir, Laufey; Gudjonsson, Thorkell; Sigurdsson, Stefan

    2017-07-05

    % CpG methylation was found to be statistically significantly associated with reduced survival (HR = 2.3; P = 0.012). By thresholding at the clinically relevant CpG methylation level (>20%), we find the incidence of ALKBH3 promoter methylation to be 5% (13 out of 265). ALKBH3 is a novel addition to the catalogue of DNA repair genes found inactivated in breast cancer. Our results underscore a link between defective alkylation repair and breast cancer which, additionally, is found in association with poor disease outcome.

  18. Entanglement entropy for (3+1)-dimensional topological order with excitations

    Science.gov (United States)

    Wen, Xueda; He, Huan; Tiwari, Apoorv; Zheng, Yunqin; Ye, Peng

    2018-02-01

    Excitations in (3+1)-dimensional [(3+1)D] topologically ordered phases have very rich structures. (3+1)D topological phases support both pointlike and stringlike excitations, and in particular the loop (closed string) excitations may admit knotted and linked structures. In this work, we ask the following question: How do different types of topological excitations contribute to the entanglement entropy or, alternatively, can we use the entanglement entropy to detect the structure of excitations, and further obtain the information of the underlying topological order? We are mainly interested in (3+1)D topological order that can be realized in Dijkgraaf-Witten (DW) gauge theories, which are labeled by a finite group G and its group 4-cocycle ω ∈H4[G ;U(1 ) ] up to group automorphisms. We find that each topological excitation contributes a universal constant lndi to the entanglement entropy, where di is the quantum dimension that depends on both the structure of the excitation and the data (G ,ω ) . The entanglement entropy of the excitations of the linked/unlinked topology can capture different information of the DW theory (G ,ω ) . In particular, the entanglement entropy introduced by Hopf-link loop excitations can distinguish certain group 4-cocycles ω from the others.

  19. Microscopic origin of the 1.3 G0 conductance observed in oxygen-doped silver quantum point contacts

    KAUST Repository

    Tu, Xingchen

    2014-11-21

    © 2014 AIP Publishing LLC. Besides the peak at one conductance quantum, G0, two additional features at ∼0.4 G0 and ∼1.3 G0 have been observed in the conductance histograms of silver quantum point contacts at room temperature in ambient conditions. In order to understand such feature, here we investigate the electronic transport and mechanical properties of clean and oxygen-doped silver atomic contacts by employing the non-equilibrium Green\\'s function formalism combined with density functional theory. Our calculations show that, unlike clean Ag single-atom contacts showing a conductance of 1 G0, the low-bias conductance of oxygen-doped Ag atomic contacts depends on the number of oxygen impurities and their binding configuration. When one oxygen atom binds to an Ag monatomic chain sandwiched between two Ag electrodes, the low-bias conductance of the junction always decreases. In contrast, when the number of oxygen impurities is two and the O-O axis is perpendicular to the Ag-Ag axis, the transmission coefficients at the Fermi level are, respectively, calculated to be 1.44 for the junction with Ag(111) electrodes and 1.24 for that with Ag(100) electrodes, both in good agreement with the measured value of ∼1.3 G0. The calculated rupture force (1.60 nN for the junction with Ag(111) electrodes) is also consistent with the experimental value (1.66 ± 0.09 nN), confirming that the measured ∼1.3 G0 conductance should originate from Ag single-atom contacts doped with two oxygen atoms in a perpendicular configuration.

  20. VLBI-simulations for the estimation of degree-three Love and Shida numbers h3 and l3

    Science.gov (United States)

    Mendes Cerveira, P. J.; Boehm, J.; Wresnik, J.; Spicakova, H.; Schuh, H.

    2007-12-01

    For the displacement due to solid Earth tides, the IERS Conventions 2003 recommend several corrections to nominal values. One of these corrections is the in-phase contribution by using the real Love and Shida numbers h3 and l3 at all degree-3 tides, where only the contribution of the moon is relevant. The maximum predicted radial displacement is in the order of 1.7 mm. The nominal values are 0.292 for h3, and 0.015 for l3, respectively. Using realistic station and source catalogues, we simulated VLBI (Very Long Baseline Interferometry) group time delays, with a white noise going up to 2 cm, and taking into account the solid Earth tides displacement. Goal of this study was to investigate whether degree-3 Love and Shida numbers can be unambiguously determined from VLBI observations. Therefore, several setups w.r.t., e.g., station constellation, cutoff angle, time span, sampling interval, and different levels of white noise were tested. Attention was put into the separability and correlation between the degree-2 and degree-3 Love and Shida numbers.

  1. Case study of chondrule alteration with IR spectroscopy in NWA 2086 CV3 meteorite

    Science.gov (United States)

    Kereszturi, A.; Gyollai, I.; Szabó, M.

    2015-02-01

    Analyzing the alteration in an olivine chondrule of the NWA 2086 CV3 meteorite, infrared spectral, electron microprobe and optical microscopic observations were correlated to each other. The intensity and wavelength positions of olivine peaks changed characteristically with the progression of alteration and related Fe/Mg substitution inward of the chondrule. Moderate to good correlations were identified between Fo% composition and positions of 830 and 860 cm-1 IR peaks. The disappearance of 1020 cm-1 peak by structural change happens already at a low level alteration without changing the optical appearance of the mineral. The existence of the 980 cm-1 peak is found to be an indicator of the intact phase of olivine. While profiles perpendicular to the chondrule's perimeter showed that the alteration progressed 15-20 μm distance inward without observable fractures (probablly by some diffusion related process), the "alteration distance" from various obvious fractures inside the chondrule was only 3-5 μm distance. These observations suggest that the substitution was more effective close to the matrix, and also related to some fluids that although were able to circulate along the large internal fractures too, did not produce such strong substitution there, like what happened close to the matrix. It was also demonstrated that the poorly exploited contact mode observations with ATR based reflection method in infrared spectroscopy provide a useful tool to analyze the alteration at micrometer scale without much sample preparation, and enable identifying alterations already at such a low level where the olivines still look optically intact.

  2. 3G Standards

    DEFF Research Database (Denmark)

    Saugstrup, Dan; Henten, Anders

    2006-01-01

    Purpose – The main purpose of this paper is to analyze which standard/technology will win the 3G mobile markets. In addition, two sub topics are examined. First, which kind of victory will it be – will one technological solution be all-dominating or is co-existence more likely? Second, which....... Originality/value – The paper is based on the understanding that a vast array of different factors in a complex dynamic environment goes into the determination of the outcome of such standardization games. However, the battle between 3G standards has already reached a level, where relatively certain...... predictions can be made. And, the paper contributes with a methodologically based discussion concerning the outcome of the battle between 3G standards....

  3. YOUNG REMNANTS OF TYPE Ia SUPERNOVAE AND THEIR PROGENITORS: A STUDY OF SNR G1.9+0.3

    International Nuclear Information System (INIS)

    Chakraborti, Sayan; Childs, Francesca; Soderberg, Alicia

    2016-01-01

    SNe Ia, with their remarkably homogeneous light curves and spectra, have been used as standardizable candles to measure the accelerating expansion of the universe. Yet, their progenitors remain elusive. Common explanations invoke a degenerate star (white dwarf) that explodes upon almost reaching the Chandrasekhar limit, by either steadily accreting mass from a companion star or violently merging with another degenerate star. We show that circumstellar interaction in young Galactic supernova remnants can be used to distinguish between these single and double degenerate (DD) progenitor scenarios. Here we propose a new diagnostic, the surface brightness index, which can be computed from theory and compared with Chandra and Very Large Array (VLA) observations. We use this method to demonstrate that a DD progenitor can explain the decades-long flux rise and size increase of the youngest known galactic supernova remnant (SNR), G1.9+0.3. We disfavor a single degenerate scenario for SNR G1.9+0.3. We attribute the observed properties to the interaction between a steep ejecta profile and a constant density environment. We suggest using the upgraded VLA, ASKAP, and MeerKAT to detect circumstellar interaction in the remnants of historical SNe Ia in the Local Group of galaxies. This may settle the long-standing debate over their progenitors

  4. YOUNG REMNANTS OF TYPE Ia SUPERNOVAE AND THEIR PROGENITORS: A STUDY OF SNR G1.9+0.3

    Energy Technology Data Exchange (ETDEWEB)

    Chakraborti, Sayan; Childs, Francesca; Soderberg, Alicia, E-mail: schakraborti@post.harvard.edu [Institute for Theory and Computation, Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States)

    2016-03-01

    SNe Ia, with their remarkably homogeneous light curves and spectra, have been used as standardizable candles to measure the accelerating expansion of the universe. Yet, their progenitors remain elusive. Common explanations invoke a degenerate star (white dwarf) that explodes upon almost reaching the Chandrasekhar limit, by either steadily accreting mass from a companion star or violently merging with another degenerate star. We show that circumstellar interaction in young Galactic supernova remnants can be used to distinguish between these single and double degenerate (DD) progenitor scenarios. Here we propose a new diagnostic, the surface brightness index, which can be computed from theory and compared with Chandra and Very Large Array (VLA) observations. We use this method to demonstrate that a DD progenitor can explain the decades-long flux rise and size increase of the youngest known galactic supernova remnant (SNR), G1.9+0.3. We disfavor a single degenerate scenario for SNR G1.9+0.3. We attribute the observed properties to the interaction between a steep ejecta profile and a constant density environment. We suggest using the upgraded VLA, ASKAP, and MeerKAT to detect circumstellar interaction in the remnants of historical SNe Ia in the Local Group of galaxies. This may settle the long-standing debate over their progenitors.

  5. Provenance metadata gathering and cataloguing of EFIT++ code execution

    Energy Technology Data Exchange (ETDEWEB)

    Lupelli, I., E-mail: ivan.lupelli@ccfe.ac.uk [CCFE, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Muir, D.G.; Appel, L.; Akers, R.; Carr, M. [CCFE, Culham Science Centre, Abingdon, Oxon OX14 3DB (United Kingdom); Abreu, P. [Instituto de Plasmas e Fusão Nuclear, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa (Portugal)

    2015-10-15

    Highlights: • An approach for automatic gathering of provenance metadata has been presented. • A provenance metadata catalogue has been created. • The overhead in the code runtime is less than 10%. • The metadata/data size ratio is about ∼20%. • A visualization interface based on Gephi, has been presented. - Abstract: Journal publications, as the final product of research activity, are the result of an extensive complex modeling and data analysis effort. It is of paramount importance, therefore, to capture the origins and derivation of the published data in order to achieve high levels of scientific reproducibility, transparency, internal and external data reuse and dissemination. The consequence of the modern research paradigm is that high performance computing and data management systems, together with metadata cataloguing, have become crucial elements within the nuclear fusion scientific data lifecycle. This paper describes an approach to the task of automatically gathering and cataloguing provenance metadata, currently under development and testing at Culham Center for Fusion Energy. The approach is being applied to a machine-agnostic code that calculates the axisymmetric equilibrium force balance in tokamaks, EFIT++, as a proof of principle test. The proposed approach avoids any code instrumentation or modification. It is based on the observation and monitoring of input preparation, workflow and code execution, system calls, log file data collection and interaction with the version control system. Pre-processing, post-processing, and data export and storage are monitored during the code runtime. Input data signals are captured using a data distribution platform called IDAM. The final objective of the catalogue is to create a complete description of the modeling activity, including user comments, and the relationship between data output, the main experimental database and the execution environment. For an intershot or post-pulse analysis (∼1000

  6. Provenance metadata gathering and cataloguing of EFIT++ code execution

    International Nuclear Information System (INIS)

    Lupelli, I.; Muir, D.G.; Appel, L.; Akers, R.; Carr, M.; Abreu, P.

    2015-01-01

    Highlights: • An approach for automatic gathering of provenance metadata has been presented. • A provenance metadata catalogue has been created. • The overhead in the code runtime is less than 10%. • The metadata/data size ratio is about ∼20%. • A visualization interface based on Gephi, has been presented. - Abstract: Journal publications, as the final product of research activity, are the result of an extensive complex modeling and data analysis effort. It is of paramount importance, therefore, to capture the origins and derivation of the published data in order to achieve high levels of scientific reproducibility, transparency, internal and external data reuse and dissemination. The consequence of the modern research paradigm is that high performance computing and data management systems, together with metadata cataloguing, have become crucial elements within the nuclear fusion scientific data lifecycle. This paper describes an approach to the task of automatically gathering and cataloguing provenance metadata, currently under development and testing at Culham Center for Fusion Energy. The approach is being applied to a machine-agnostic code that calculates the axisymmetric equilibrium force balance in tokamaks, EFIT++, as a proof of principle test. The proposed approach avoids any code instrumentation or modification. It is based on the observation and monitoring of input preparation, workflow and code execution, system calls, log file data collection and interaction with the version control system. Pre-processing, post-processing, and data export and storage are monitored during the code runtime. Input data signals are captured using a data distribution platform called IDAM. The final objective of the catalogue is to create a complete description of the modeling activity, including user comments, and the relationship between data output, the main experimental database and the execution environment. For an intershot or post-pulse analysis (∼1000

  7. New extended (G'/G)-expansion method to solve nonlinear evolution equation: the (3 + 1)-dimensional potential-YTSF equation.

    Science.gov (United States)

    Roshid, Harun-Or-; Akbar, M Ali; Alam, Md Nur; Hoque, Md Fazlul; Rahman, Nizhum

    2014-01-01

    In this article, a new extended (G'/G) -expansion method has been proposed for constructing more general exact traveling wave solutions of nonlinear evolution equations with the aid of symbolic computation. In order to illustrate the validity and effectiveness of the method, we pick the (3 + 1)-dimensional potential-YTSF equation. As a result, abundant new and more general exact solutions have been achieved of this equation. It has been shown that the proposed method provides a powerful mathematical tool for solving nonlinear wave equations in applied mathematics, engineering and mathematical physics.

  8. [Correlation analysis of G870A CCND1 gene polymorphism with digestive system tumors].

    Science.gov (United States)

    Yang, Shu-Min; Shi, Ya-Lin

    2016-11-20

    To study the correlation of G870A CCND1 gene polymorphism and digestive system tumors. From August 2010 to August 2014, 164 digestive system cancer patients (including 82 patients with gastric cancer and 82 with colorectal cancer) and 82 healthy subjects (control group) were examined with PCR-restriction fragment length polymorphism (PCR-RFLP). The distribution of CCND1 gene G870A frequency in the 3 groups and its association with tumor staging and grading were analyzed. The frequencies of the GG, GA and AA genotypes in G870A CCND1 gene loci in patients with gastric cancer and colorectal cancer differed significantly from those in the control group (Pdigestive system tumors (Pdigestive system cancer risk than the GG genotype (Pdigestive system tumors. The allele A is associated with an increased risk of digestive system tumors and correlated with the tumor differentiation and staging of the tumor.

  9. Effect of Radiofrequency Radiation Emitted from 2G and 3G Cell Phone on Developing Liver of Chick Embryo – A Comparative Study

    Science.gov (United States)

    Swer, Rijied Thompson; Anbalagan, J.; Rajesh, Bhargavan

    2017-01-01

    Introduction The increasing scientific evidence of various health hazards on exposure of Radiofrequency Radiation (RFR) emitted from both the cell phones and base stations have caused significant media attention and public discussion in recent years. The mechanism of interaction of RF fields with developing tissues of children and fetuses may be different from that of adults due to their smaller physical size and variation in tissue electromagnetic properties. The present study may provide an insight into the basic mechanisms by which RF fields interact with developing tissues in an embryo. Aim To evaluate the possible tissue and DNA damage in developing liver of chick embryo following chronic exposure to Ultra-High Frequency/Radiofrequency Radiation (UHF/RFR) emitted from 2G and 3G cell phone. Materials and Methods Fertilized chick embryos were incubated in four groups. Group A-experimental group exposed to 2G radiation (60 eggs), Group B- experimental group exposed to 3G radiation (60 eggs), Group C- sham exposed control group (60 eggs) and Group D– control group (48 eggs). On completion of scheduled duration, the embryos were collected and processed for routine histological studies to check structural changes in liver. The nuclear diameter and karyorrhexis changes of hepatocytes were analysed using oculometer and square reticule respectively. The liver procured from one batch of eggs from all the four groups was subjected to alkaline comet assay technique to assess DNA damage. The results were compared using one-way ANOVA test. Results In our study, the exposure of developing chick embryos to 2G and 3G cell phone radiations caused structural changes in liver in the form of dilated sinusoidal spaces with haemorrhage, increased vacuolations in cytoplasm, increased nuclear diameter and karyorrhexis and significantly increased DNA damage. Conclusion The chronic exposure of chick embryo liver to RFR emitted from 2G and 3G cell phone resulted in various structural

  10. Informal information for web-based engineering catalogues

    Science.gov (United States)

    Allen, Richard D.; Culley, Stephen J.; Hicks, Ben J.

    2001-10-01

    Success is highly dependent on the ability of a company to efficiently produce optimal designs. In order to achieve this companies must minimize time to market and possess the ability to make fully informed decisions at the early phase of the design process. Such decisions may include the choice of component and suppliers, as well as cost and maintenance considerations. Computer modeling and electronic catalogues are becoming the preferred medium for the selection and design of mechanical components. In utilizing these techniques, the designer demands the capability to identify, evaluate and select mechanical components both quantitatively and qualitatively. Quantitative decisions generally encompass performance data included in the formal catalogue representation. It is in the area of qualitative decisions that the use of what the authors call 'Informal Information' is of crucial importance. Thus, 'Informal Information' must often be incorporated into the selection process and selection systems. This would enable more informed decisions to be made quicker, without the need for information retrieval via discussion with colleagues in the design environment. This paper provides an overview of the use of electronic information in the design of mechanical systems, including a discussion of limitations of current technology. The importance of Informal Information is discussed and the requirements for association with web based electronic catalogues are developed. This system is based on a flexible XML schema and enables the storage, classification and recall of Informal Information packets. Furthermore, a strategy for the inclusion of Informal Information is proposed, and an example case is used to illustrate the benefits.

  11. HbA1c variability in type 2 diabetes is associated with the occurrence of new-onset albuminuria within three years.

    Science.gov (United States)

    Dorajoo, Sreemanee Raaj; Ng, Joceline Shi Ling; Goh, Jessica Hui Fen; Lim, Su Chi; Yap, Chun Wei; Chan, Alexandre; Lee, Joyce Yu Chia

    2017-06-01

    To evaluate the association between HbA1c coefficient of variation (HbA1c-CV) and 3-year new-onset albuminuria risk. A retrospective cohort study involving 716 normoalbuminuric type 2 diabetes patients was conducted between 2010 and 2014. HbA1c-CV was used to categorize patients into low, moderate or high variability groups. Multivariate logistic models were constructed and validated. Integrated discrimination (IDI) and net reclassification (NRI) improvement indices were used to quantify the added predictive value of HbA1c-CV. The mean age of our cohort was 56.1±12.9years with a baseline HbA1c of 8.3±1.3%. Over 3-years of follow-up, 35.2% (n=252) developed albuminuria. An incremental risk of albuminuria was observed with moderate (6.68-13.43%) and high (above 13.44%) HbA1c-CV categories demonstrating adjusted odds ratios of 1.63 (1.12-2.38) and 3.80 (2.10-6.97) for 3-year new-onset albuminuria, respectively. Including HbA1c-CV for 3-year new-onset albuminuria prediction improved model discrimination (IDI: 0.023, NRI: 0.293, pHbA1c-CV improves 3-year prediction of new-onset albuminuria. Together with mean HbA1c, baseline urine albumin-to-creatinine ratio and presence of hypertension, accurate 3-year new-onset albuminuria prediction may be possible. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. A mini-catalogue of metal corrosion products studied by Raman microscopy

    International Nuclear Information System (INIS)

    Bouchard, M.; Smith, D.C.

    2000-01-01

    Full text.The extensive development of physical methods of analysis since the beginning of this century has revolutionised the classical observation techniques most frequently used by the archaeologist. Raman Microscopy (RM) appears to be one of the most promising tools due to the many advantages that it offers: e.g. non-destructive, in situ, micro-analysis. RM is being applied to many archaeological fields as well as to industrial or environmental sectors. In relation with parallel studies made on the identification of corrosion products on archaeological materials, and according to the principal condition for the RM characterisation of an unknown product being the comparison of its Raman spectrum with known standard spectra, the essential aim of this study is to build a mini-catalogue of standard corrosion products susceptible to be found on metallic objects; these could be from archaeological as well as from modern contexts. However, it is noted that the identification of a corrosion product may suggest either an urgent intervention from the restoration team (in the case of active corrosion products), or a stabilisation of the corrosion layer if this is considered to be a protective layer. All the standard samples are natural minerals coming from the Museum National d'Histoire Naturelle in Paris (France) and correspond to the corrosion products most frequently found on metals such copper, zinc, lead or tin. These samples have been analyzed by RM and also confirmed by powder x-ray diffraction analysis. This catalogue, including more than 30 standard species corresponding to the most common metal corrosion products, is very useful for the different studies in progress in collaboration with different archaeological metal restoration teams. The near future will probably see a mobile Raman Microprobe (MRM) equipped with many different mini-catalogues on the site of a corroded mettalic bridge, a corroded canalisation or under the sea to rapidly identify the different

  13. Development of end group for 1.3 GHZ nine cell SCRF cavity

    International Nuclear Information System (INIS)

    Yedle, Ajay; Bagre, Manish; Maurya, Tilak; Yadav, Anand; Puntambekar, Avinash; Mahawar, Ashish; Mohania, Praveen; Shrivastava, Purushottam; Joshi, Satish Chandra

    2013-01-01

    Raja Ramanna Centre for Advanced Technology (RRCAT) is developing 1.3 GHz superconducting radio frequency (SCRF) cavities as part of SCRF technology development. The 1.3 GHz nine cell SCRF cavities comprise of multiple cells and end groups at each end. These end groups are important parts of a multi-cell cavity. They serve as interface for putting RF power to cavity, pick up the signal for various RF control and have higher order modes (HOM) coupler. The multiple parts with intricate shape, complex weld geometry and stringent RF requirements pose various challenges in their manufacturing. This paper presents the efforts on development of end groups comprising of manufacturing of various parts, their fabrication by electron beam welding process and pre-qualification including mechanical measurement, vacuum leak testing RF measurement. (author)

  14. Dicty_cDB: Contig-U14329-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 2 0.41 3 ( DV113252 ) CV03005B1A12.f1 CV03-normalized library Euphorbia... 32 0.42 3 ( CB610770 ) ALBEDO0002_IaF_C05 Mature...NA non acclimated Bluecrop library Vaccin... 34 0.057 3 ( AL645532 ) Mouse DNA sequence from clone RP23-295E...formis cDNA, cleaving embryo clone:m... 38 0.085 2 ( CF811518 ) NA72 cDNA non acclimated Bluecrop library...TTEAF92THC Tetrahymena thermophila EST library, c... 44 0.22 2 ( AC096661 ) Homo sapiens BAC clone RP11-61G2...4425 ) TTEAV71THB Tetrahymena thermophila EST library, c... 44 0.27 2 ( CQ870098 ) Sequence 519 from Patent

  15. PAI-1 4G/5G polymorphism contributes to cancer susceptibility: evidence from meta-analysis.

    Science.gov (United States)

    Wang, Shangqian; Cao, Qiang; Wang, Xiaoxiang; Li, Bingjie; Tang, Min; Yuan, Wanqing; Fang, Jianzheng; Qian, Jian; Qin, Chao; Zhang, Wei

    2013-01-01

    The plasminogen activator inhibitor-1 (PAI-1) is expressed in many cancer cell types and allows the modulation of cancer growth, invasion and angiogenesis. To date, studies investigated the association between a functional polymorphism in PAI-1 (4G/5G) and risk of cancer have shown inclusive results. A meta-analysis based on 25 case-control studies was performed to address this issue. Odds ratios (OR) with corresponding 95% confidence intervals (CIs) were used to assess the association. The statistical heterogeneity across studies was examined with I(2) test. Overall, a significant increased risk of cancer was associated with the PAI-1 4G/4G polymorphism for the allele contrast (4G vs. 5G: OR = 1.10, CI = 1.03-1.18, I(2) = 49.5%), the additive genetic model (4G/4G vs. 5G/5G: OR = 1.21, CI = 1.06-1.39, I(2) = 51.9%), the recessive genetic model (4G/4G vs. 4G/5G+5G/5G: OR = 1.11, CI = 1.04-1.18, I(2) = 20.8%). In the subgroup analysis by ethnicity, the results indicated that individuals with 4G/4G genotype had a significantly higher cancer risk among Caucasians (4G/4G vs. 5G/5G: OR = 1.31, 95%CI = 1.09-1.59, I(2) = 59.6%; 4G/4G vs. 4G/5G: OR = 1.12, 95%CI = 1.04-1.21, I(2) = 3.6%; recessive model: OR = 1.12, 95%CI = 1.05-1.21, I(2) = 25.3%). The results of the present meta-analysis support an association between the PAI-1 4G/5G polymorphism and increasing cancer risk, especially among Caucasians, and those with 4G allele have a high risk to develop colorectal cancer and endometrial cancer.

  16. One-pot synthesis of a Ni–Mn3O4 nanocomposite for supercapacitors

    International Nuclear Information System (INIS)

    Xu, Guo-rong; Shi, Jin-jin; Dong, Wen-hao; Wen, Ya; Min, Xiang-ping; Tang, An-ping

    2015-01-01

    Highlights: • Ni–Mn 3 O 4 nanocomposites have been synthesized simply. • Mn 3 O 4 particles were deposited on surface of Ni particles with OH functional groups. • Ni–Mn 3 O 4 composites could be quickly conditioned to birnessite-type MnO 2 . • A specific capacitance of 230 F g1 was obtained for Ni (17.3%)–Mn 3 O 4 nanocomposite. - Abstract: Ni–Mn 3 O 4 nanocomposite has been prepared successfully by chemical oxidation in an alkaline solution of Mn 2+ on the surface of Ni nanoparticles with OH functional groups using one-pot method. The obtained Ni–Mn 3 O 4 nanocomposite was characterized using a scanning electron microscope (SEM), a transmission electron microscope (TEM), X-ray diffraction (XRD) analysis and various electrochemical techniques, such as cyclic voltammetry (CV), galvanostatic charge/discharge (GC/D) and electrochemical impedance spectroscopy (EIS). The average crystal sizes of Mn 3 O 4 were found to decrease linearly with increasing Ni content in the Ni–Mn 3 O 4 composite. The Ni–Mn 3 O 4 nanocomposite could be easily conditioned and inverted to birnessite-type MnO 2 . A specific capacitance of 230 F g1 (based on pure Mn 3 O 4 ) was obtained for the Ni (17.3%)–Mn 3 O 4 nanocomposite at a current rate of 0.25 A g1 , and 94% of the initial capacitance was retained after 1000 GC/D cycles at a current rate of 1 A g1 . It is concluded that the Ni–Mn 3 O 4 nanocomposite is a promising electrode materials for supercapacitors

  17. Microscopic origin of the 1.3 G0 conductance observed in oxygen-doped silver quantum point contacts

    KAUST Repository

    Tu, Xingchen; Wang, Minglang; Sanvito, Stefano; Hou, Shimin

    2014-01-01

    © 2014 AIP Publishing LLC. Besides the peak at one conductance quantum, G0, two additional features at ∼0.4 G0 and ∼1.3 G0 have been observed in the conductance histograms of silver quantum point contacts at room temperature in ambient conditions

  18. Process and results of the development of an ICNP® Catalogue for Cancer Pain

    Directory of Open Access Journals (Sweden)

    Marisaulina Wanderley Abrantes de Carvalho

    2013-10-01

    Full Text Available This was a methodological study conducted to describe the process and results of the development of an International Classification for Nursing Practice (ICNP® Catalogue for Cancer Pain. According to the International Council of Nurses (ICN, this catalogue contains a subset of nursing diagnoses, outcomes, and interventions to document the implementation of the nursing process in cancer patients. This catalogue was developed in several steps according to the guidelines recommended by the ICN. As a result, 68 statements on nursing diagnoses/outcomes were obtained, which were classified according to the theoretical model for nursing care related to cancer pain into physical (28, psychological (29, and sociocultural and spiritual (11 aspects. A total of 116 corresponding nursing interventions were obtained. The proposed ICNP® Catalogue for Cancer Pain aims to provide safe and systematic orientation to nurses who work in this field, thus improving the quality of patient care and facilitating the performance of the nursing process.

  19. Vienna International Centre Library Film and Video Catalogue: Peaceful applications of nuclear energy 1928-1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-12-31

    The catalogue lists films and videos which are available on free loan from Vienna International Centre Library for educational, non-commercial, non-profit showings involving no admission charges or appeals for funds. Much of the material listed has been donated to the IAEA by the Governments of Member States. The items are arranged in the catalogue by number. The catalogue also includes a title index and a subject index

  20. Vienna International Centre Library Film and Video Catalogue: Peaceful applications of nuclear energy 1928-1998

    International Nuclear Information System (INIS)

    1998-01-01

    The catalogue lists films and videos which are available on free loan from Vienna International Centre Library for educational, non-commercial, non-profit showings involving no admission charges or appeals for funds. Much of the material listed has been donated to the IAEA by the Governments of Member States. The items are arranged in the catalogue by number. The catalogue also includes a title index and a subject index

  1. Annotated catalogue of the flowering plants of São Tomé and Príncipe

    Directory of Open Access Journals (Sweden)

    E. Figueiredo

    2011-12-01

    Full Text Available A catalogue of the flowering plants of the islands of São Tomé and Príncipe (Gulf of Guinea is presented. Flowering plant diversity figures are updated to: 135 families (20 introduced, 624 genera (172 introduced, 1 104 species (301 introduced plus 15 additional infraspecific taxa. At present 119 taxa (107 species and 12 infraspecific taxa are known to be endemic to the two islands. The catalogue includes accepted names, synonyms used in recent literature, common names, voucher specimens and information on habit and habitat and on plant uses, particularly medicinally.

  2. Recurrent meningitis in a child with IgG3 subclass deficiency.

    Science.gov (United States)

    Vehapoglu, Aysel; Ozgurhan, Gamze; Demir, Aysegul Dogan; Uzuner, Selcuk; Nursoy, Mustafa Atilla; Turkmen, Serdar

    2014-08-01

    Recurrent meningitis is an uncommon life-threatening condition. Here, the case of a 6-year-old boy is reported who had two episodes of meningitis with an IgG3 subclass deficiency. The boy had aseptic meningitis at the age of 3 years, followed by bacterial meningitis at the age of 4 years. Primary immunoglobulin deficiencies are a group of disorders associated with an increased incidence and/or severity of infection. Recurrent infections, sinusitis, bronchitis, and pneumonia are the most frequently observed illnesses in patients with IgG subclass deficiencies, of which an IgG3 subclass deficiency is the most common, especially in adults. Although cases of recurrent viral or bacterial meningitis have been reported, herein a patient is presented with recurrence of aseptic and bacterial meningitis 1 year after the initial episode. Some researchers recommend that all children with episodes of recurrent meningitis should be screened for primary immunoglobulin or complement deficiencies.

  3. Isotopic coherence of refractory inclusions from CV and CK meteorites: Evidence from multiple isotope systems

    Science.gov (United States)

    Shollenberger, Quinn R.; Borg, Lars E.; Render, Jan; Ebert, Samuel; Bischoff, Addi; Russell, Sara S.; Brennecka, Gregory A.

    2018-05-01

    Calcium-aluminum-rich inclusions (CAIs) are the oldest dated materials in the Solar System and numerous previous studies have revealed nucleosynthetic anomalies relative to terrestrial rock standards in many isotopic systems. However, most of the isotopic data from CAIs has been limited to the Allende meteorite and a handful of other CV3 chondrites. To better constrain the isotopic composition of the CAI-forming region, we report the first Sr, Mo, Ba, Nd, and Sm isotopic compositions of two CAIs hosted in the CK3 desert meteorites NWA 4964 and NWA 6254 along with two CAIs from the CV3 desert meteorites NWA 6619 and NWA 6991. After consideration of neutron capture processes and the effects of hot-desert weathering, the Sr, Mo, Ba, Nd, and Sm stable isotopic compositions of the samples show clearly resolvable nucleosynthetic anomalies that are in agreement with previous results from Allende and other CV meteorites. The extent of neutron capture, as manifested by shifts in the observed 149Sm-150Sm isotopic composition of the CAIs is used to estimate the neutron fluence experienced by some of these samples and ranges from 8.40 × 1013 to 2.11 × 1015 n/cm2. Overall, regardless of CAI type or host meteorite, CAIs from CV and CK chondrites have similar nucleosynthetic anomalies within analytical uncertainty. We suggest the region that CV and CK CAIs formed was largely uniform with respect to Sr, Mo, Ba, Nd, and Sm isotopes when CAIs condensed and that CAIs hosted in CV and CK meteorites are derived from the same isotopic reservoir.

  4. Evaluation of a competitive enzyme-linked immunosorbent assay for measurements of soluble HLA-G protein.

    Science.gov (United States)

    Rasmussen, M; Dahl, M; Buus, S; Djurisic, S; Ohlsson, J; Hviid, T V F

    2014-08-01

    The human leukocyte antigen (HLA) class Ib molecule, HLA-G, has gained increased attention because of its assumed important role in immune regulation. The HLA-G protein exists in several soluble isoforms. Most important are the actively secreted HLA-G5 full-length isoform generated by alternative splicing retaining intron 4 with a premature stop codon, and the cleavage of full-length membrane-bound HLA-G1 from the cell surface, so-called soluble HLA-G1 (sHLA-G1). A specific and sensitive immunoassay for measurements of soluble HLA-G is mandatory for conceivable routine testing and research projects. We report a novel method, a competitive immunoassay, for measuring HLA-G5/sHLA-G1 in biological fluids. The sHLA-G immunoassay is based upon a competitive enzyme-linked immunosorbent assay (ELISA) principle. It includes a recombinant sHLA-G1 protein in complex with β2-microglobulin and a peptide as a standard, biotinylated recombinant sHLA-G1 as an indicator, and the MEM-G/9 anti-HLA-G monoclonal antibody (mAb) as the capture antibody. The specificity and sensitivity of the assay were evaluated. Testing with different recombinant HLA class I proteins and different anti-HLA class I mAbs showed that the sHLA-G immunoassay was highly specific. Optimal combinations of competitor sHLA-G1 and capture mAb concentrations were determined. Two versions of the assay were tested. One with a relatively wide dynamic range from 3.1 to 100.0 ng/ml, and another more sensitive version ranging from 1.6 to 12.5 ng/ml. An intra-assay coefficient of variation (CV) of 15.5% at 88 ng/ml and an inter-assay CV of 23.1% at 39 ng/ml were determined. An assay based on the competitive sHLA-G ELISA may be important for measurements of sHLA-G proteins in several conditions: assisted reproduction, organ transplantation, cancer, and certain pregnancy complications, both in research studies and possibly in the future also for clinical routine use. © 2014 John Wiley & Sons A/S. Published by John Wiley

  5. SphinX catalogue of small flares and brightenings

    Science.gov (United States)

    Gryciuk, Magdalena; Sylwester, Janusz; Gburek, Szymon; Siarkowski, Marek; Mrozek, Tomasz; Kepa, Anna

    The Solar Photometer in X-rays (SphinX) was designed to measure soft X-ray solar emission in the energy range between 1 keV and 15 keV. The instrument operated from February until November 2009 aboard CORONAS-Photon satellite, during the phase of extraordinary low minimum of solar activity. Thanks to its very high sensitivity SphinX was able to record large number of tiny flares and brightenings. A catalogue of events observed by SphinX will be presented. Results of statistical analysis of events’ characteristics will be discussed.

  6. The sixth catalogue of galactic Wolf-Rayet stars, their past and present

    International Nuclear Information System (INIS)

    Hucht, K.A. van der; Conti, P.S.; Lundstroem, I.; Stenholm, B.

    1981-01-01

    This paper presents the Sixth Catalogue of galactic Wolf-Rayet stars (Pop I), a short history on the five earlier WR catalogues, improved spectral classification, finding charts, a discussion on related objects, and a review of the current statur of Wolf-Rayet star research. The appendix presents a bibliography on most of the Wolf-Rayet literature published since 1867. (orig.)

  7. Effect of quarterly treatments with a chlorhexidine and a fluoride varnish on approximal caries in caries-susceptible teenagers: a 3-year clinical study.

    Science.gov (United States)

    Petersson, L G; Magnusson, K; Andersson, H; Almquist, B; Twetman, S

    2000-01-01

    The aim of this study was to compare the effect of two different dental varnishes on approximal caries incidence in teenagers with proven caries susceptibility during a 3-year period. Two hundred 13- to 14-year-old subjects exhibiting at least two approximal enamel caries lesions were selected to take part in the study. One hundred and eighty subjects participated after informed consent and were randomly assigned to two equally sized groups. One group was treated with a fluoride varnish (FV, Fluor Protector) containing 0.1% F every 3rd month and the participants of the other group were treated in the same mode with a chlorhexidine varnish (CV, Cervitec((R))) containing 1% chlorhexidine and 1% thymol. In total, each subject was treated 12 times during the experimental period. Approximal caries including enamel lesions (DMFS(appr)) were recorded from four bitewing radiographs exposed at the start and end of the study. The mean (+/-SD) caries prevalence at baseline was 2.2+/-3.4 in the FV group and 2.5+/-4.0 in the CV group. After 3 years, the average approximal caries incidence was 2.7+/-3.1 and 3.1+/-3.5 in the FV and CV groups, respectively. The differences at baseline and after 3 years were not statistically significant. In conclusion, treatments every 3rd month with either a fluoride- or a chlorhexidine/thymol-containing varnish showed a promising effect with low approximal caries incidence and progression in teenagers with proven caries susceptibility.

  8. Catalogue of high-mass X-ray binaries in the Galaxy (4th edition)

    NARCIS (Netherlands)

    Liu, Q.Z.; van Paradijs, J.; van den Heuvel, E.P.J.

    2006-01-01

    We present a new edition of the catalogue of high-mass X-ray binaries in the Galaxy. The catalogue contains source name(s), coordinates, finding chart, X-ray luminosity, system parameters, and stellar parameters of the components and other characteristic properties of 114 high-mass X-ray binaries,

  9. Global Roads Open Access Data Set, Version 1 (gROADSv1)

    Data.gov (United States)

    National Aeronautics and Space Administration — The Global Roads Open Access Data Set, Version 1 (gROADSv1) was developed under the auspices of the CODATA Global Roads Data Development Task Group. The data set...

  10. Polarisation properties of irradiated ammonia (NH3 and ND3) at 1 K and 25 kG

    International Nuclear Information System (INIS)

    Riechert, H.

    1982-11-01

    Dynamic Nuclear Polarisation (DNP) of irradiated ammonia was examined in some detail at 1 K and 25 kG. In continuation of earlier studies conducted in Bonn, it was attempted to gain information about the prevailing mechanism of DNP in this material. Therefore the frequency dependence of DNP in NH 3 , of deuterons and unsubstituted protons in ND 3 , as well as the polarising time tau and the relaxation time T 1 in NH 3 were measured. Also the shape of the deuteron polarisation signal observed in ND 3 is discussed. The polarisation measurements in ND 3 rule out the equal spin temperature (EST) behaviour of proton and deuteron DNP that is observed in most of the currently used target materials. It is attempted to explain the observations with a differential solid state effect model. Results of calculations for NH 3 and ND 3 incorporating the measured EPR-spectra are presented. (orig.)

  11. The Flynn effect, group differences, and g loadings

    NARCIS (Netherlands)

    te Nijenhuis, J.

    2013-01-01

    Flynn effect gains are predominantly driven by environmental factors. Might these factors also be responsible for group differences in intelligence? Group differences in intelligence have been clearly shown to strongly correlate with g loadings. The empirical studies on whether the pattern of Flynn

  12. Antibody response in vaccinated pregnant mares to recent G3BP[12] and G14P[12] equine rotaviruses

    Directory of Open Access Journals (Sweden)

    Nemoto Manabu

    2012-11-01

    Full Text Available Abstract Background Both the G3P[12] and the G14P[12] type of equine group A rotavirus (RVA have recently become predominant in many countries, including Japan. G3 types are classified further into G3A and G3B. The G3A viruses have been circulating in Europe, Australia, and Argentina, and the G3B viruses have been circulating in Japan. However, only an inactivated vaccine containing a single G3BP[12] strain is commercially available in Japan. To assess the efficacy of the current vaccine against recently circulating equine RVA strains, we examined antibody responses in pregnant mares to recent G3BP[12] and G14P[12] strains by virus neutralization test. Findings After vaccination in five pregnant mares, the geometric mean serum titers of virus-neutralizing antibody to recent G3BP[12] strains increased 5.3- to 7.0-fold and were similar to that against homologous vaccine strain. Moreover, antibody titers to recent G14P[12] strains were also increased 3.0- to 3.5-fold. Conclusions These results suggest that inoculation of mares with the current vaccine should provide foals with virus-neutralizing antibodies against not only the G3BP[12] but also the G14P[12] RVA strain via the colostrum.

  13. Which finite simple groups are unit groups?

    DEFF Research Database (Denmark)

    Davis, Christopher James; Occhipinti, Tommy

    2014-01-01

    We prove that if G is a finite simple group which is the unit group of a ring, then G is isomorphic to either (a) a cyclic group of order 2; (b) a cyclic group of prime order 2^k −1 for some k; or (c) a projective special linear group PSLn(F2) for some n ≥ 3. Moreover, these groups do all occur a...

  14. Tumultuous relationship between the human immunodeficiency virus type 1 viral infectivity factor (Vif) and the human APOBEC-3G and APOBEC-3F restriction factors.

    Science.gov (United States)

    Henriet, Simon; Mercenne, Gaëlle; Bernacchi, Serena; Paillart, Jean-Christophe; Marquet, Roland

    2009-06-01

    The viral infectivity factor (Vif) is dispensable for human immunodeficiency virus type 1 (HIV-1) replication in so-called permissive cells but is required for replication in nonpermissive cell lines and for pathogenesis. Virions produced in the absence of Vif have an aberrant morphology and an unstable core and are unable to complete reverse transcription. Recent studies demonstrated that human APOBEC-3G (hA3G) and APOBEC-3F (hA3F), which are selectively expressed in nonpermissive cells, possess strong anti-HIV-1 activity and are sufficient to confer a nonpermissive phenotype. Vif induces the degradation of hA3G and hA3F, suggesting that its main function is to counteract these cellular factors. Most studies focused on the hypermutation induced by the cytidine deaminase activity of hA3G and hA3F and on their Vif-induced degradation by the proteasome. However, recent studies suggested that several mechanisms are involved both in the antiviral activity of hA3G and hA3F and in the way Vif counteracts these antiviral factors. Attempts to reconcile the studies involving Vif in virus assembly and stability with these recent findings suggest that hA3G and hA3F partially exert their antiviral activity independently of their catalytic activity by destabilizing the viral core and the reverse transcription complex, possibly by interfering with the assembly and/or maturation of the viral particles. Vif could then counteract hA3G and hA3F by excluding them from the viral assembly intermediates through competition for the viral genomic RNA, by regulating the proteolytic processing of Pr55(Gag), by enhancing the efficiency of the reverse transcription process, and by inhibiting the enzymatic activities of hA3G and hA3F.

  15. Produção e composição química da Brachiaria brizantha cv. MG-4 sob efeito de adubação com NPK = Yield and chemical composition of Brachiaria brizantha cv. MG-4 under the effect of NPK fertilization

    Directory of Open Access Journals (Sweden)

    Thaisa Grazielle Radin Magalhães Teles

    2011-04-01

    Full Text Available O objetivo deste trabalho foi avaliar os efeitos de combinações de doses de nitrogênio, fósforo e potássio sobre a produção de matéria seca e composição química de Brachiaria brizantha cv. MG-4. O experimento foi composto por 16 tratamentos de NPK, conforme matriz experimental Plan Puebla II, distribuídos em delineamento inteiramentecasualizado com cinco repetições. Utilizou-se um Argissolo Vermelho-Amarelo Distrófico Arênico e, como fonte de N, P e K, foram utilizados sulfato de amônio e uréia, superfosfato triplo e cloreto de potássio, respectivamente. O material coletado foi separado em colmo e folha, e pré-seco para a determinação da produção matéria seca de folhas (MSF, colmos (MSC e total (MST, teor de proteína bruta (PB, N, P e K. A adubação promoveu incremento na produção da B. brizantha cv. MG-4, cujas doses de 360-370-360 g vaso-1 de NPK, respectivamente, proporcionaram 95% da maior produção de MST observada. As produtividades máximas foram nas doses de 373, 407 e 317 mg dm-3 de N de solo para MST, MSF e MSC, respectivamente. As doses de N proporcionaram incrementos nos teores de PB das folhas. As adubações fosfatada e nitrogenada proporcionaram aumento na quantidade acumulada de N, P e K na B. brizantha cv. MG-4.The objective of this work was to evaluate the effects of combinations of nitrogen (N, phosphorus (P and potassium (K on the dry matter yield and chemical composition of Brachiaria brizantha cv. MG-4. The experiment consisted of 16 combination levels of NPK, according to experimental matrix Plan Puebla II, in a completely randomized design with five replications. It used a dystrophic RedYellow Sand-Argisol; ammonium and urea sulfate, triple super phosphate and potassium chloride were used as sources of N, P and K, respectively. The harvested material was separated into leaves and stem and submitted to dry matter yield (DMY evaluations of the aerial part, crude protein (CP and determination of

  16. VizieR Online Data Catalog: Catalogue of Stellar Spectral Classifications (Skiff, 2009-2016)

    Science.gov (United States)

    Skiff, B. A.

    2014-10-01

    Morgan & Abt 'MKA' paper (1972AJ.....77...35M) not appearing in the two later lists are added. Keenan made continual adjustments to the standards lists up to the time of his death. Thus the late-type standards comprise those marked as high-weight standards in the 1989 Perkins catalogue (1989ApJS...71..245K = III/150); the revised S-type standards in collaboration with Boeshaar (1980ApJS...43..379K); plus the carbon standards and class IIIb 'clump giants' in collaboration with Barnbaum (1996ApJS..105..419B and 1999ApJ...518..859K). In addition, I have made use of the final types by Keenan up to January 2000 shown at the Ohio State Web site (http://www.astronomy.ohio-state.edu/MKCool), accessed in autumn 2003. Though the present file contains all the stars in these lists, only those marked as standards are flagged as such. Garrison's list of MK 'anchor points' might also be consulted in this regard (1994mpyp.conf....3G, and http://www.astro.utoronto.ca/~garrison/mkstds.html). The catalogue includes for the first time results from many large-scale objective-prism spectral surveys done at Case, Stockholm, Crimea, Abastumani, and elsewhere. The stars in these surveys were usually identified only on charts or by other indirect means, and have been overlooked heretofore because of the difficulty in recovering the stars. More complete results from these separate publications, including notes and identifications, have been made available to the CDS, and are kept at the Lowell Observatory ftp area (ftp://ftp.lowell.edu/pub/bas/starcats). Not all of these stars are present in SIMBAD. As a 'living catalogue', an attempt will be made to keep up with current literature, and to extend the indexing of citations back in time. (2 data files).

  17. VizieR Online Data Catalog: Catalogue of Stellar Spectral Classifications (Skiff, 2009-2012)

    Science.gov (United States)

    Skiff, B. A.

    2010-11-01

    Morgan & Abt 'MKA' paper (1972AJ.....77...35M) not appearing in the two later lists are added. Keenan made continual adjustments to the standards lists up to the time of his death. Thus the late-type standards comprise those marked as high-weight standards in the 1989 Perkins catalogue (1989ApJS...71..245K = III/150); the revised S-type standards in collaboration with Boeshaar (1980ApJS...43..379K); plus the carbon standards and class IIIb 'clump giants' in collaboration with Barnbaum (1996ApJS..105..419B and 1999ApJ...518..859K). In addition, I have made use of the final types by Keenan up to January 2000 shown at the Ohio State Web site (http://www.astronomy.ohio-state.edu/MKCool), accessed in autumn 2003. Though the present file contains all the stars in these lists, only those marked as standards are flagged as such. Garrison's list of MK 'anchor points' might also be consulted in this regard (1994mpyp.conf....3G, and http://www.astro.utoronto.ca/~garrison/mkstds.html). The catalogue includes for the first time results from many large-scale objective-prism spectral surveys done at Case, Stockholm, Crimea, Abastumani, and elsewhere. The stars in these surveys were usually identified only on charts or by other indirect means, and have been overlooked heretofore because of the difficulty in recovering the stars. More complete results from these separate publications, including notes and identifications, have been made available to the CDS, and are kept at the Lowell Observatory ftp area (ftp://ftp.lowell.edu/pub/bas/starcats). Not all of these stars are present in SIMBAD. As a 'living catalogue', an attempt will be made to keep up with current literature, and to extend the indexing of citations back in time. (2 data files).

  18. VizieR Online Data Catalog: Catalogue of Stellar Spectral Classifications (Skiff, 2009-2014)

    Science.gov (United States)

    Skiff, B. A.

    2014-10-01

    Morgan & Abt 'MKA' paper (1972AJ.....77...35M) not appearing in the two later lists are added. Keenan made continual adjustments to the standards lists up to the time of his death. Thus the late-type standards comprise those marked as high-weight standards in the 1989 Perkins catalogue (1989ApJS...71..245K = III/150); the revised S-type standards in collaboration with Boeshaar (1980ApJS...43..379K); plus the carbon standards and class IIIb 'clump giants' in collaboration with Barnbaum (1996ApJS..105..419B and 1999ApJ...518..859K). In addition, I have made use of the final types by Keenan up to January 2000 shown at the Ohio State Web site (http://www.astronomy.ohio-state.edu/MKCool), accessed in autumn 2003. Though the present file contains all the stars in these lists, only those marked as standards are flagged as such. Garrison's list of MK 'anchor points' might also be consulted in this regard (1994mpyp.conf....3G, and http://www.astro.utoronto.ca/~garrison/mkstds.html). The catalogue includes for the first time results from many large-scale objective-prism spectral surveys done at Case, Stockholm, Crimea, Abastumani, and elsewhere. The stars in these surveys were usually identified only on charts or by other indirect means, and have been overlooked heretofore because of the difficulty in recovering the stars. More complete results from these separate publications, including notes and identifications, have been made available to the CDS, and are kept at the Lowell Observatory ftp area (ftp://ftp.lowell.edu/pub/bas/starcats). Not all of these stars are present in SIMBAD. As a 'living catalogue', an attempt will be made to keep up with current literature, and to extend the indexing of citations back in time. (2 data files).

  19. VizieR Online Data Catalog: Catalogue of Stellar Spectral Classifications (Skiff, 2009-2013)

    Science.gov (United States)

    Skiff, B. A.

    2013-05-01

    Morgan & Abt 'MKA' paper (1972AJ.....77...35M) not appearing in the two later lists are added. Keenan made continual adjustments to the standards lists up to the time of his death. Thus the late-type standards comprise those marked as high-weight standards in the 1989 Perkins catalogue (1989ApJS...71..245K = III/150); the revised S-type standards in collaboration with Boeshaar (1980ApJS...43..379K); plus the carbon standards and class IIIb 'clump giants' in collaboration with Barnbaum (1996ApJS..105..419B and 1999ApJ...518..859K). In addition, I have made use of the final types by Keenan up to January 2000 shown at the Ohio State Web site (http://www.astronomy.ohio-state.edu/MKCool), accessed in autumn 2003. Though the present file contains all the stars in these lists, only those marked as standards are flagged as such. Garrison's list of MK 'anchor points' might also be consulted in this regard (1994mpyp.conf....3G, and http://www.astro.utoronto.ca/~garrison/mkstds.html). The catalogue includes for the first time results from many large-scale objective-prism spectral surveys done at Case, Stockholm, Crimea, Abastumani, and elsewhere. The stars in these surveys were usually identified only on charts or by other indirect means, and have been overlooked heretofore because of the difficulty in recovering the stars. More complete results from these separate publications, including notes and identifications, have been made available to the CDS, and are kept at the Lowell Observatory ftp area (ftp://ftp.lowell.edu/pub/bas/starcats). Not all of these stars are present in SIMBAD. As a 'living catalogue', an attempt will be made to keep up with current literature, and to extend the indexing of citations back in time. (2 data files).

  20. O{sub 2}(X{sup 3}Σ{sub g}{sup −}) and O{sub 2}(a{sup 1}Δ{sub g}) charge exchange with simple ions

    Energy Technology Data Exchange (ETDEWEB)

    Ziółkowski, Marcin; Schatz, George C., E-mail: schatz@chem.northwestern.edu [Department of Chemistry, Northwestern University, Evanston, Illinois 60208-3113 (United States); Viggiano, A. A.; Midey, Anthony [Air Force Research Laboratory, Space Vehicles Directorate, 3500 Aberdeen Ave, Kirtland AFB, New Mexico 87117 (United States); Dotan, Itzhak [Air Force Research Laboratory, Space Vehicles Directorate, 3500 Aberdeen Ave, Kirtland AFB, New Mexico 87117 (United States); Open University of Israel, 108 Ravutski St., Raanana 43107 (Israel)

    2014-06-07

    We present theory and experiments which describe charge transfer from the X{sup 3}Σ{sub g}{sup −} and a{sup 1}Δ{sub g} states of molecular oxygen and atomic and molecular cations. Included in this work are new experimental results for O{sub 2}(a{sup 1}Δ{sub g}) and the cations O{sup +}, CO{sup +}, Ar{sup +}, and N{sub 2}{sup +}, and new theory based on complete active space self-consistent field method calculations and an extended Langevin model to calculate rate constants for ground and excited O{sub 2} reacting with the atomic ions Ar{sup +}, Kr{sup +}, Xe{sup +}, Cl{sup +}, and Br{sup +}. The T-shaped orientation of the (X − O{sub 2}){sup +} potential surface is used for the calculations, including all the low lying states up to the second singlet state of the oxygen molecule b{sup 1}Σ{sub g}{sup +}. The calculated rate constants for both O{sub 2}(X{sup 3}Σ{sub g}{sup −}) and O{sub 2}(a{sup 1}Δ{sub g}) show consistent trends with the experimental results, with a significant dependence of rate constant on charge transfer exothermicity that does not depend strongly on the nature of the cation. The comparisons with theory show that partners with exothermicities of about 1 eV have stronger interactions with O{sub 2}, leading to larger Langevin radii, and also that more of the electronic states are attractive rather than repulsive, leading to larger rate constants. Rate constants for charge transfer involving O{sub 2}(a{sup 1}Δ{sub g}) are similar to those for O{sub 2}(X{sup 3}Σ{sub g}{sup −}) for a given exothermicity ignoring the electronic excitation of the O{sub 2}(a{sup 1}Δ{sub g}) state. This means (and the electronic structure calculations support) that the ground and excited states of O{sub 2} have about the same attractive interactions with ions.

  1. CERN Technical Training: Autumn 2007 Course Catalogue

    CERN Multimedia

    2007-01-01

    The following course sessions are scheduled in the framework of the CERN Technical Training Program 2007. You may find the full updated Technical Training course programme in our web-catalogue. OFFICE SOFTWARE CERN EDMS MTF en pratique F 4.9 1/2 d WORD 2007 (Short Course III) - How to work with long documents E/F 14.9 1/2 d FrontPage 2003 - niveau 1 E/F 17-18.9 2 d WORD 2007 - Niveau1: ECDL F 20.-21-9 2 d ACCESS 2007 - Level 1: ECDL E 20-21.9 2 d EXCEL 2007 (Short Course I) - How to work with Formulae E/F 21.9 1/2 d CERN EDMS Introduction E 24.9 1 d Java 2 Enterprise Edition - Part 1: Web Applications E 24-25.9 2 d Outlook 2007 (Short Course II) - Calendar, Tasks and Notes E/F 28.9 1/2 d Outlook 2007 (Short Course III) - Meeting and Delegation ...

  2. Characterization of a novel gene encoding ankyrin repeat domain from Cotesia vestalis polydnavirus (CvBV)

    International Nuclear Information System (INIS)

    Shi Min; Chen Yafeng; Huang Fang; Liu Pengcheng; Zhou Xueping; Chen Xuexin

    2008-01-01

    Cotesia vestalis (Haliday) is an endoparasitoid of Plutella xylostella (L.) larvae and injects a polydnavirus (CvBV) into its host during oviposition. In this report we describe the characterization of a gene (CvBV805) and its products. CvBV805 is located on the segment S8 of CvBV genome; it has a size of 909 bp and encodes a predicted protein of 125 amino acids. This protein contains an ankyrin repeat domain with a high degree of similarity with IκB-like genes. Gene transcripts were detected in extracts of the host as early as 2 h post-parasitization (p.p.) and continued to be detected through 24 h. Tissue-specific expression patterns showed that CvBV805 might be involved in early host immunosuppression. CvBV805 was detected in parasitized hosts at 12 h p.p. and in rBac-eGFP-CvBV805-infected Tn-5B1-4 cells at 72 h.p.i. by using western blots analysis. The size of the protein expressed in the host hemocytes and infected Tn-5B1-4 cells was 17 kDa and 56 kDa (including eGFP), respectively, which nearly corresponded with the predicted molecular weight (14.31 kDa) of CvBV805, suggesting that the protein did not undergo extensive post-translational modification. The protein was confirmed to be present within the nuclear region in hemocytes of the parasitized P. xylostella larvae at 48 h p.p. using confocal laser scanning microscopy

  3. Novel circulatory connection from the acupoint Zhong Wan(CV12 to pancreas

    Directory of Open Access Journals (Sweden)

    Minsoo Kim

    2008-03-01

    Full Text Available Objectives : Demonstrating a novel circulatory path from the acupoint(CV12 to the pancreas. Method : Alcian blue(1% solution, 20μl, pH 7.4 was injected into the acupoint(CV12. Two hours later the surfaces of internal organs were observed by using a stereomicroscope. Results : Alcian blue arrived and colored the omental fat band(OFB on the pancreas. The OFB connected the head and tail of the pancreas, the pancreas and the spleen, and the pancreas and the stomach. Conclusion : The existence of a novel circulatory path from the acupoint CV12 to the pancreas and its OFB was demonstrated.

  4. Group G streptococcal myositis in a patient with myeloproliferative neoplasm

    Directory of Open Access Journals (Sweden)

    Monica Midha, MD MBS

    2016-01-01

    Full Text Available While many cases of streptococcal infection are due to Lancefield groups A and B, there has been a rise in reported cases of infections due to group G streptococcus. We present a case of an individual with a hematologic malignancy who developed myositis secondary to group G streptococcus, with no clearly identifiable source of infection. The patient was managed with antibiotic therapy rather than surgical intervention due to high surgical risk related to severe thrombocytopenia. Targeted antibiotics initiated early in the course of disease may prevent the need for surgical intervention. Early diagnosis and treatment are critical to avoid the high morbidity and mortality of life-threatening infections caused by group G streptococcus.

  5. INFORMATION FOR USERS OF NUTS, BOLTS, SCREWS, NAILS AND RIVETS (SCEM GROUP 47)

    CERN Multimedia

    Logistics Group

    2002-01-01

    We should like to remind users that, since the closure of the self-service stores, nuts, bolts, screws, nails and rivets (Group 47 of the Stores Catalogue) can be obtained, in smaller packages than via EDH, from the 'Emergency Counter' in the Central Stores (Building 73, R-002) upon presentation of a duly completed hard-copy Materials Request form. The 'Emergency Counter' is open Mondays to Fridays from 7.30 a.m. to 11.50 a.m. and from 1.00 p.m. to 4.20 p.m. Information concerning the available packages can be found under the appropriate SCEM reference number in the Stores Catalogue. Logistics Group SPL Division

  6. IgG4-related cardiovascular disease. The emerging role of cardiovascular imaging

    Energy Technology Data Exchange (ETDEWEB)

    Mavrogeni, Sophie, E-mail: soma13@otenet.gr; Markousis-Mavrogenis, George; Kolovou, Genovefa

    2017-01-15

    Highlights: • Assessment of serum IgG4 levels and involved organ biopsy are necessary for diagnosis of IgG4-related disease. • CV involvement may manifest as cardiac pseudotumors, inflammatory periaortitis, coronary arteritis and/or pericarditis. • Echocardiography and vascular ultrasound are the most commonly used non-invasive, non-radiating imaging techniques. • CT can assess periarteritis and coronary artery aneurysms, while 18FDG-PET shows FDG uptake at the area of the lesion. • CMR offers an integrated imaging of CV system, including assessment of disease acuity, extent of fibrosis and can guide further treatment. - Abstract: Immunoglobulin 4-related disease (IgG4-related disease) is a systemic inflammatory disease that presents with increases of serum IgG4. It may affect various systems, including the cardiovascular (CV) system. Assessment of serum IgG4 levels and involved organ biopsy are necessary for diagnosis. IgG4-related disease is characterized by fibrosclerosis, lymphocytic infiltration and presence of IgG4-positive plasma cells. The disease usually responds to treatment with corticosteroids and/or immunosuppressive medication. CV involvement may manifest as cardiac pseudotumors, inflammatory periaortitis, coronary arteritis and/or pericarditis. IgG4-related cardiovascular disorders can severely affect patient prognosis. Various imaging techniques, including echocardiography, Computed Tomography (CT), 18FDG-PET, Cardiovascular Magnetic Resonance (CMR) and cardiac catheterisation, have been successfully used for early disease detection and follow-up. Echocardiography and vascular ultrasound are the most commonly used non-invasive, non-radiating imaging techniques for the evaluation of IgG4-related CV disease. Periaortitis/periarteritis can be also assessed by CT, showing a soft tissue thickening around arteries. Coronary artery aneurysms can be easily diagnosed by coronary CT. In case of active periarterial or coronary artery inflammation, 18

  7. IgG4-related cardiovascular disease. The emerging role of cardiovascular imaging

    International Nuclear Information System (INIS)

    Mavrogeni, Sophie; Markousis-Mavrogenis, George; Kolovou, Genovefa

    2017-01-01

    Highlights: • Assessment of serum IgG4 levels and involved organ biopsy are necessary for diagnosis of IgG4-related disease. • CV involvement may manifest as cardiac pseudotumors, inflammatory periaortitis, coronary arteritis and/or pericarditis. • Echocardiography and vascular ultrasound are the most commonly used non-invasive, non-radiating imaging techniques. • CT can assess periarteritis and coronary artery aneurysms, while 18FDG-PET shows FDG uptake at the area of the lesion. • CMR offers an integrated imaging of CV system, including assessment of disease acuity, extent of fibrosis and can guide further treatment. - Abstract: Immunoglobulin 4-related disease (IgG4-related disease) is a systemic inflammatory disease that presents with increases of serum IgG4. It may affect various systems, including the cardiovascular (CV) system. Assessment of serum IgG4 levels and involved organ biopsy are necessary for diagnosis. IgG4-related disease is characterized by fibrosclerosis, lymphocytic infiltration and presence of IgG4-positive plasma cells. The disease usually responds to treatment with corticosteroids and/or immunosuppressive medication. CV involvement may manifest as cardiac pseudotumors, inflammatory periaortitis, coronary arteritis and/or pericarditis. IgG4-related cardiovascular disorders can severely affect patient prognosis. Various imaging techniques, including echocardiography, Computed Tomography (CT), 18FDG-PET, Cardiovascular Magnetic Resonance (CMR) and cardiac catheterisation, have been successfully used for early disease detection and follow-up. Echocardiography and vascular ultrasound are the most commonly used non-invasive, non-radiating imaging techniques for the evaluation of IgG4-related CV disease. Periaortitis/periarteritis can be also assessed by CT, showing a soft tissue thickening around arteries. Coronary artery aneurysms can be easily diagnosed by coronary CT. In case of active periarterial or coronary artery inflammation, 18

  8. AFA 2G and AFA 3G fuel rod performance analysis

    International Nuclear Information System (INIS)

    Lu Huaquan; Liu Tong; Jiao Yongjun; Pang Hua

    2002-01-01

    For 18-months fuel cycle strategy in GNPJVC DAYA BAY unit 1/2, by means of COCCINEL, the fuel rod performance for AFA 3G and AFA 2G in transition cycle is analyzed. The design criteria which should be respected in fuel rod design are included and the design methodology is introduced. All the criteria mentioned are verified and met

  9. Effects of 2G and 3G mobile phones on human alpha rhythms: Resting EEG in adolescents, young adults, and the elderly.

    Science.gov (United States)

    Croft, R J; Leung, S; McKenzie, R J; Loughran, S P; Iskra, S; Hamblin, D L; Cooper, N R

    2010-09-01

    The present study was conducted to determine whether adolescents and/or the elderly are more sensitive to mobile phone (MP)-related bioeffects than young adults, and to determine this for both 2nd generation (2G) GSM, and 3rd generation (3G) W-CDMA exposures. To test this, resting alpha activity (8-12 Hz band of the electroencephalogram) was assessed because numerous studies have now reported it to be enhanced by MP exposure. Forty-one 13-15 year olds, forty-two 19-40 year olds, and twenty 55-70 year olds were tested using a double-blind crossover design, where each participant received Sham, 2G and 3G exposures, separated by at least 4 days. Alpha activity, during exposure relative to baseline, was recorded and compared between conditions. Consistent with previous research, the young adults' alpha was greater in the 2G compared to Sham condition, however, no effect was seen in the adolescent or the elderly groups, and no effect of 3G exposures was found in any group. The results provide further support for an effect of 2G exposures on resting alpha activity in young adults, but fail to support a similar enhancement in adolescents or the elderly, or in any age group as a function of 3G exposure. 2010 Wiley-Liss, Inc.

  10. 3D gauged supergravity from SU(2) reduction of $N=1$ 6D supergravity

    CERN Document Server

    Gava, Edi; Narain, K S

    2010-01-01

    We obtain Yang-Mills $SU(2)\\times G$ gauged supergravity in three dimensions from $SU(2)$ group manifold reduction of (1,0) six dimensional supergravity coupled to an anti-symmetric tensor multiplet and gauge vector multiplets in the adjoint of $G$. The reduced theory is consistently truncated to $N=4$ 3D supergravity coupled to $4(1+\\textrm{dim}\\, G)$ bosonic and $4(1+\\textrm{dim}\\, G)$ fermionic propagating degrees of freedom. This is in contrast to the reduction in which there are also massive vector fields. The scalar manifold is $\\mathbf{R}\\times \\frac{SO(3,\\, \\textrm{dim}\\, G)}{SO(3)\\times SO(\\textrm{dim}\\, G)}$, and there is a $SU(2)\\times G$ gauge group. We then construct $N=4$ Chern-Simons $(SO(3)\\ltimes \\mathbf{R}^3)\\times (G\\ltimes \\mathbf{R}^{\\textrm{dim}G})$ three dimensional gauged supergravity with scalar manifold $\\frac{SO(4,\\,1+\\textrm{dim}G)}{SO(4)\\times SO(1+\\textrm{dim}G)}$ and explicitly show that this theory is on-shell equivalent to the Yang-Mills $SO(3)\\times G$ gauged supergravity the...

  11. A Theoretical investigation of a potential high energy density compound 3,6,7,8-tetranitro-3,6,7,8-tetraaza-tricyclo[3.1.1.1(2,4]octane

    Directory of Open Access Journals (Sweden)

    Guozheng Zhao

    2013-01-01

    Full Text Available The B3LYP/6-31G (d density functional theory (DFT method was used to study molecular geometry, electronic structure, infrared spectrum (IR and thermodynamic properties. Heat of formation (HOF and calculated density were estimated to evaluate detonation properties using Kamlet-Jacobs equations. Thermal stability of 3,6,7,8-tetranitro-3,6,7,8-tetraaza-tricyclo [3.1.1.1(2,4]octane (TTTO was investigated by calculating bond dissociation energy (BDE at the unrestricted B3LYP/6-31G(d level. Results showed the N-NO2 bond is a trigger bond during the thermolysis initiation process. The crystal structure obtained by molecular mechanics (MM methods belongs to P2(1/C space group, with cell parameters a = 8.239 Å, b = 8.079 Å, c = 16.860 Å, Z = 4 and r = 1.922 g cm-3. Both detonation velocity of 9.79 km s-1 and detonation pressure of 44.22 GPa performed similarly to CL-20. According to the quantitative standards of energetics and stability, TTTO essentially satisfies this requirement as a high energy density compound (HEDC.

  12. Promenade Among Words and Things: The Gallery as Catalogue, the Catalogue as Gallery

    Directory of Open Access Journals (Sweden)

    Mari Lending

    2015-12-01

    Full Text Available In the mid nineteenth century new casting techniques allowed for the production of huge architectural fragments. Well-selected collections could ideally display perfect series in galleries in which the visitor could wander among monuments and experience architecture history on full scale. The disembodied material of plaster was considered capable of embodying a number of modern historical taxonomies and aesthetical programs, most importantly chronology, comparison, style, and evolution. Veritable showcases of historicism, the casts could illustrate in spatial arrangements new conceptions on the history, contemporaneity and future of architecture. Plaster cast became a main medium in which to publish antiquities as novelties for grand audiences, taking the printed and published beyond the two-dimensional space of words and images. However, due to the increasing market of casts and their sheere size and weight, the reproductions as mounted in the galleries often behaved as unruly as architecture does outside curatorial control. In the end only the catalogues, the paper versions of these imaginary museums were capable to create the orders that their plaster referents constantly aspired to destroy. An important chapter in the history of the architecture museum these plaster monuments belong to a part of architectural print culture in which catalogues were curated and galleries edited. Metaphors drawn from the realm of writing saturated the discourse on the display of casts. Images and texts fluctuated and the image-objects were compared to books, paper, pages, documents and libraries but above all to illustrations inviting promenades in time and space.

  13. G+K 1Σ+/sub g/ double-minimum excited state of H2

    International Nuclear Information System (INIS)

    Glover, R.M.; Weinhold, F.

    1977-01-01

    We have obtained a Born--Oppenheimer potential curve for the previously uncharacterized third 1 Σ + /sub g/ state of H 2 , using a correlated 20-term wavefunction of generalized James--Coolidge type. We find this potential curve to have a double-minimum character, with the inner (Rydberg-like) and outer (''ionic'') wells having minima at about 1.99 and 3.30 bohr, respectively, and an intervening maximum at 2.76 bohr. Unlike the extensively studied E+F double-minimum state, the outer well here appears to be the deeper, by some 450 cm -1 in our calculation. The inner and outer minima can apparently be associated with spectral lines that in experimental tables have previously been attributed to distinct G and K electronic states. The appropriate spectroscopic term symbol of this combined state is accordingly G+K 1 Σ + /sub g/ (1ssigma3dsigma+2pπ 2 )

  14. Key technologies and concepts for beyond-3G networks

    Science.gov (United States)

    Pehkonen, Kari; Uskela, Sami; Kalliojarvi, Kari; Oksanen, Lauri; Rikkinen, Kari

    2001-10-01

    Standardization of 3rd Generation (3G) mobile communication systems has produced the first specification releases and the commercial deployment of the 3G systems has started. Whereas 1G and 2G focused on efficiently providing voice services, in 3G a lot of attention has been devoted to solutions that support both Circuit Switched (CS) and Packet Switched (PS) communication. That has called for very flexible air interface and network solutions. 3G will continue to evolve and there are already on-going standardization activities that will, for example, boost the peak data rates up to 5-10 Mbps and improve spectral efficiency by 2-4 times. In the future, 3G evolution will be going towards 10/100 Mbps peak data rates in wide/local are coverage, respectively. This will take place partly because of technical improvements of 3G radio interface solutions, but also due to network evolution which will allow the integration other radio access methods like radio LANs into the 3G system. In longer term the 3G network evolution will be going towards ALL-IP networks. As 3G evolution seems to be going towards 10 Mbps/100 Mbps peak data rates and ALL-IP networks any beyond 3G air interface or network solution should be clearly better in order to justify its technical and commercial feasibility. Given the long evolution time of 3G and integration of other radio access schemes with 3G radio we may not even see a new, complete beyond 3G system being developed. Maybe we will just witness the emergence of a new, more advanced radio access solution which will then be connected to the evolving 3G network. As 3G evolution will continue for several years to come the research targets for any beyond 3G solutions must be set very high. When it comes to air interface, we should aim at 100 Mbps peak data rates for wide area access with high mobility, and at 1 Gbps for local area access with low mobility. Regarding possible commercial launches of any beyond 3G systems or solutions they could then

  15. The WATCH solar X-ray burst catalogue

    DEFF Research Database (Denmark)

    Crosby, N.; Lund, Niels; Vilmer, N.

    1998-01-01

    The WATCH experiment aboard the GRANAT satellite provides observations of the Sun in the deka-keV range covering the years 1990 through mid-1992. An introduction to the experiment is given followed by an explanation of how the WATCH solar burst catalogue was created. The different parameters list...

  16. The ASTRODEEP Frontier Fields catalogues. II. Photometric redshifts and rest frame properties in Abell-2744 and MACS-J0416

    Science.gov (United States)

    Castellano, M.; Amorín, R.; Merlin, E.; Fontana, A.; McLure, R. J.; Mármol-Queraltó, E.; Mortlock, A.; Parsa, S.; Dunlop, J. S.; Elbaz, D.; Balestra, I.; Boucaud, A.; Bourne, N.; Boutsia, K.; Brammer, G.; Bruce, V. A.; Buitrago, F.; Capak, P.; Cappelluti, N.; Ciesla, L.; Comastri, A.; Cullen, F.; Derriere, S.; Faber, S. M.; Giallongo, E.; Grazian, A.; Grillo, C.; Mercurio, A.; Michałowski, M. J.; Nonino, M.; Paris, D.; Pentericci, L.; Pilo, S.; Rosati, P.; Santini, P.; Schreiber, C.; Shu, X.; Wang, T.

    2016-05-01

    Aims: We present the first public release of photometric redshifts, galaxy rest frame properties and associated magnification values in the cluster and parallel pointings of the first two Frontier Fields, Abell-2744 and MACS-J0416. The released catalogues aim to provide a reference for future investigations of extragalactic populations in these legacy fields: from lensed high-redshift galaxies to cluster members themselves. Methods: We exploit a multiwavelength catalogue, ranging from Hubble Space Telescope (HST) to ground-based K and Spitzer IRAC, which is specifically designed to enable detection and measurement of accurate fluxes in crowded cluster regions. The multiband information is used to derive photometric redshifts and physical properties of sources detected either in the H-band image alone, or from a stack of four WFC3 bands. To minimize systematics, median photometric redshifts are assembled from six different approaches to photo-z estimates. Their reliability is assessed through a comparison with available spectroscopic samples. State-of-the-art lensing models are used to derive magnification values on an object-by-object basis by taking into account sources positions and redshifts. Results: We show that photometric redshifts reach a remarkable ~3-5% accuracy. After accounting for magnification, the H-band number counts are found to be in agreement at bright magnitudes with number counts from the CANDELS fields, while extending the presently available samples to galaxies that, intrinsically, are as faint as H ~ 32-33, thanks to strong gravitational lensing. The Frontier Fields allow the galaxy stellar mass distribution to be probed, depending on magnification, at 0.5-1.5 dex lower masses with respect to extragalactic wide fields, including sources at Mstar ~ 107-108 M⊙ at z > 5. Similarly, they allow the detection of objects with intrinsic star formation rates (SFRs) >1 dex lower than in the CANDELS fields reaching 0.1-1 M⊙/yr at z ~ 6-10. The

  17. Stem Cell Mobilization with G-CSF versus Cyclophosphamide plus G-CSF in Mexican Children.

    Science.gov (United States)

    Meraz, José Eugenio Vázquez; Arellano-Galindo, José; Avalos, Armando Martínez; Mendoza-García, Emma; Jiménez-Hernández, Elva

    2016-01-01

    Fifty-six aphaereses were performed in 23 pediatric patients with malignant hematological and solid tumors, following three different protocols for PBPC mobilization and distributed as follows: A: seventeen mobilized with 4 g/m(2) of cyclophosphamide (CFA) and 10 μg/kg/day of granulocyte colony stimulating factor (G-CSF), B: nineteen with CFA + G-CSF, and C: twenty only with G-CSF when the WBC count exceeded 10 × 10(9)/L. The average number of MNC/kg body weight (BW)/aphaeresis was 0.4 × 10(8) (0.1-1.4), 2.25 × 10(8) (0.56-6.28), and 1.02 × 10(8) (0.34-2.5) whereas the average number of CD34+ cells/kg BW/aphaeresis was 0.18 × 10(6)/kg (0.09-0.34), 1.04 × 10(6) (0.19-9.3), and 0.59 × 10(6) (0.17-0.87) and the count of CFU/kg BW/aphaeresis was 1.11 × 10(5) (0.31-2.12), 1.16 × 10(5) (0.64-2.97), and 1.12 × 10(5) (0.3-6.63) in groups A, B, and C, respectively. The collection was better in group B versus group A (p = 0.007 and p = 0.05, resp.) and in group C versus group A (p = 0.08 and p = 0.05, resp.). The collection of PBPCs was more effective in the group mobilized with CFM + G-CSF when the WBC exceeded 10 × 10(3)/μL in terms of MNC and CD34+ cells and there was no toxicity of the chemotherapy.

  18. Functional interaction between type III-secreted protein IncA of Chlamydophila psittaci and human G3BP1.

    Science.gov (United States)

    Borth, Nicole; Litsche, Katrin; Franke, Claudia; Sachse, Konrad; Saluz, Hans Peter; Hänel, Frank

    2011-01-31

    Chlamydophila (Cp.) psittaci, the causative agent of psittacosis in birds and humans, is the most important zoonotic pathogen of the family Chlamydiaceae. These obligate intracellular bacteria are distinguished by a unique biphasic developmental cycle, which includes proliferation in a membrane-bound compartment termed inclusion. All Chlamydiaceae spp. possess a coding capacity for core components of a Type III secretion apparatus, which mediates specific delivery of anti-host effector proteins either into the chlamydial inclusion membrane or into the cytoplasm of target eukaryotic cells. Here we describe the interaction between Type III-secreted protein IncA of Cp. psittaci and host protein G3BP1 in a yeast two-hybrid system. In GST-pull down and co-immunoprecipitation experiments both in vitro and in vivo interaction between full-length IncA and G3BP1 were shown. Using fluorescence microscopy, the localization of G3BP1 near the inclusion membrane of Cp. psittaci-infected Hep-2 cells was demonstrated. Notably, infection of Hep-2 cells with Cp. psittaci and overexpression of IncA in HEK293 cells led to a decrease in c-Myc protein concentration. This effect could be ascribed to the interaction between IncA and G3BP1 since overexpression of an IncA mutant construct disabled to interact with G3BP1 failed to reduce c-Myc concentration. We hypothesize that lowering the host cell c-Myc protein concentration may be part of a strategy employed by Cp. psittaci to avoid apoptosis and scale down host cell proliferation.

  19. A catalogue of criteria helping to evaluate the consequences of technological developments

    International Nuclear Information System (INIS)

    Peters, H.P.

    1985-01-01

    The catalogue of criteria worked out by the paper abstracted helps to give a systematic and detailed description of the consequences implied by the different alternative energy sources and systems. It particularly allows to evaluate the four energy paths developed by the Enquete Commission. The consequences described refer to energy systems, energy demand, energy supply and the effects of the respective paths on society and individuals. The relevant criteria were chosen with the help of different groups such as trade associations, trade unions or nature protection organizations. (DG) [de

  20. Germination of somatic embryos of Psidium guajava L. cv. Cuban Red Dwarf EEA 18-40 in temporary immersion systems

    Directory of Open Access Journals (Sweden)

    Jorge Vilchez Perozo

    2001-04-01

    Full Text Available Somatic embryo germination of Psidium guajava L. cv. Cuban Red Dwarf EEA 18-40 in temporary immersion systems (TIS, in which somatic embryos were cultured in the heart-torpedo stage in MS mediun at mayor half strength salt and suplemented with: 0.25 mg.l-1 of 6-bencilaminopurine (6-BAP, 10 mg.l-1 of Biobras-6 (analogous of brasinoesteriode and 20 g.l-1 of sucrose. As control was used solid cultivation medium (2.5 g.l-1 Gellan gum, Spectrum® of same composition to the one used in the TIS. The variables germination percentage and fresh weight were evaluated statistically. After ten weeks of cultivation the largest values in germination percentage (91.04% and fresh weight (1.22 g were obtained in the TIS, being statistically different to those obtained in solid medium (9.79% and 1.03 g, respectively. Key words: in vitro plant, guayaba, regeneration, RITA®,somatic embryogenesis

  1. APOBEC3G-induced hypermutation of human immunodeficiency virus type-1 is typically a discrete "all or nothing" phenomenon

    DEFF Research Database (Denmark)

    Armitage, Andrew E; Deforche, Koen; Chang, Chih-Hao

    2012-01-01

    The rapid evolution of Human Immunodeficiency Virus (HIV-1) allows studies of ongoing host-pathogen interactions. One key selective host factor is APOBEC3G (hA3G) that can cause extensive and inactivating Guanosine-to-Adenosine (G-to-A) mutation on HIV plus-strand DNA (termed hypermutation). HIV...... can inhibit this innate anti-viral defense through binding of the viral protein Vif to hA3G, but binding efficiency varies and hypermutation frequencies fluctuate in patients. A pivotal question is whether hA3G-induced G-to-A mutation is always lethal to the virus or if it may occur at sub......-lethal frequencies that could increase viral diversification. We show in vitro that limiting-levels of hA3G-activity (i.e. when only a single hA3G-unit is likely to act on HIV) produce hypermutation frequencies similar to those in patients and demonstrate in silico that potentially non-lethal G-to-A mutation rates...

  2. Instant OpenCV for iOS

    CERN Document Server

    Kornyakov, Kirill

    2013-01-01

    Filled with practical, step-by-step instructions and clear explanations for the most important and useful tasks. This book uses a very practical approach, with each recipe and their associated sample projects or examples focusing on a particular aspect of the technology.This book is intended for OpenCV developers who are interested in porting their applications to the iOS platform. Basic experience with OpenCV, computer vision, Objective C, and other iOS tools is encouraged.

  3. Visible-light-driven g-C{sub 3}N{sub 4}/Ti{sup 3+}-TiO{sub 2} photocatalyst co-exposed {0 0 1} and {1 0 1} facets and its enhanced photocatalytic activities for organic pollutant degradation and Cr(VI) reduction

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Dan; Zhang, Gaoke, E-mail: gkzhang@whut.edu.cn; Wan, Zhen

    2015-12-15

    Graphical abstract: Schematic illustration for the mechanism of photo-generated charge carrier transfers in g-C{sub 3}N{sub 4}/Ti{sup 3+}-TiO{sub 2} photocatalyst and its visible-light photocatalytic performance. - Highlights: • g-C{sub 3}N{sub 4}/Ti{sup 3+}-TiO{sub 2} composite co-exposed {0 0 1} and {1 0 1} facets of TiO{sub 2} was synthesized. • RhB and Cr(VI) aqueous solutions were used to evaluate the photocatalytic activities. • h{sup +} and ·O{sub 2}{sup −} are the critical reactive species in the degradation of RhB solution. • Surface heterojunction of co-exposed {1 0 1} and {0 0 1} facets improve the separation. - Abstract: Novel g-C{sub 3}N{sub 4/}Ti{sup 3+}-TiO{sub 2} photocatalyst co-exposed {0 0 1} and {1 0 1} facets of TiO{sub 2} was synthesized via a hydrothermal–sonication assisted strategy. The photocatalytic activities of the as-obtained photocatalyst were evaluated by the degradation of rhodamine B (RhB) and the reduction of Cr(VI) under visible-light irradiation. It was found that the g-C{sub 3}N{sub 4}/Ti{sup 3+}-TiO{sub 2} composites with 6 wt% g-C{sub 3}N{sub 4} exhibited the highest visible-light photocatalytic efficiency, which is also higher than the pure g-C{sub 3}N{sub 4} and Ti{sup 3+}-TiO{sub 2}. A possible photocatalytic mechanism was discussed on the basis of the theoretical analyses and scavenger experiments. Results show that holes (h{sup +}) and superoxide anions (·O{sub 2}{sup −}) reactive species participated in the degradation of RhB solution over the g-C{sub 3}N{sub 4}/Ti{sup 3+}-TiO{sub 2} composites. The enhanced photocatalytic activities of g-C{sub 3}N{sub 4}/Ti{sup 3+}-TiO{sub 2} composites can be attributed to the wide optical adsorption of g-C{sub 3}N{sub 4} and Ti{sup 3+} as well as the effectively separation and transportation of photo-generated electrons and holes pairs, which was resulted from the surface heterojunction between the g-C{sub 3}N{sub 4} and Ti{sup 3+}-TiO{sub 2} nanosheets co-exposed {1

  4. Nuclear Knowledge Management Case Studies Catalogue “NKM CSC”

    International Nuclear Information System (INIS)

    Atieh, T.

    2016-01-01

    Full text: Over the past several years, many nuclear organizations in IAEA’s Member States have accumulated considerable experiences and achievements in the development and application of nuclear knowledge management (NKM) methodology and tools to improve their organizational performance. The IAEA NKM Section has initiated a project entitled “NKM Case Studies Catalogue (NKM CSC)” to capture and document, as well as preserve NKM experience and facilitate its sharing among NKM practitioners and experts. This is done through collection and preservation of information of relevant experiential knowledge in “case study” format. The catalogue will therefore support community of practice mechanisms. An input template is currently under development and will be used to help contributors in Member States who are providing concise set of information about their respective case studies. This information will be made searchable and easily retrievable through a platform that supports collaboration among NKM practitioners and experts. It is planned to launch the Nuclear Knowledge Management Case Studies Catalogue “NKM CSC” at the occasion of the “Third International Conference on Nuclear Knowledge Management—Challenges and Approaches, 7-–11 November 2016, Vienna, Austria”, and to include the accepted case studies submitted to this Conference. (author

  5. Catalogue of type specimens of fungi and lichens deposited in the Herbarium of the University of Granada (Spain).

    Science.gov (United States)

    Vizoso, M Teresa; Quesada, Carmen

    2015-01-01

    A catalogue of types from the Herbarium of the University of Granada has not previously been compiled. As a result, a search of these collections in order to compile digital images for preservation and publication yielded a large number of formerly unrecognized types. This dataset contains the specimen records from the catalogue of the nomenclature types of fungi and lichens in the Herbarium of the University of Granada, Spain. These herbarium specimens are included in the GDA and GDAC collections, acronyms from Index Herbariorum (Thiers 2014). At this time, the type collection of fungi and lichens contains 88 type specimens of 49 nominal taxa, most from Agaricales and the genus Cortinarius, described from the western Mediterranean, mainly Spain, by the following authors: V.Antonin, J.Ballarà, A.Bidaud, G.F.Bills, M.Bon, C.Cano, M.Casares, G.Chevassut, M.Contu, F.Esteve-Raventós, R.Galán, L.Guzmán-Dávalos, R.Henry, E.Horak, R.Mahiques, G.Malençon, P.Moënne-Loccoz, G.Moreno, A.Ortega, F.Palazón, V.N.Suárez.-Santiago, A.Vêzda, J.Vila, and M.Villareal. For each specimen, the locality indication, species name, observation date, collector, type status, related information, associated sequences, other catalogue numbers related to each type, and image URL are recorded. The dataset is associated with an image collection named "Colección de imágenes de los tipos nomenclaturales de hongos, líquenes, musgos y algas incluidos en el Herbario de la Universidad de Granada (GDA y GDAC)" (Vizoso and Quesada 2013) which is housed and accessible at the Global Biodiversity Information Facility in Spain (GBIF.ES) Hosting and Publishing Service "Biodiversity Image Portal of Spanish collections" and is also available at the Herbarium of University of Granada institutional web (Vizoso 2014a, Vizoso 2014b). That image collection contains 113 images, of which 56 correspond to the nomenclature types of 49 taxa (47 fungi, 2 lichens), the rest of the images in this collection

  6. Renormalization group aspects of 3-dimensional Pure U(1) lattice gauge theory

    International Nuclear Information System (INIS)

    Gopfert, M.; Mack, G.

    1983-01-01

    A few surprises in a recent study of the 3-dimensional pure U(1) lattice gauge theory model, from the point of view of the renormalization group theory, are discussed. Since the gauge group U(1) of this model is abelian, the model is subject to KramersWannier duality transformation. One obtains a ferromagnet with a global symmetry group Z. The duality transformation shows that the surface tension alpha of the model equals the strong tension of the U(1) gauge model. A theorem to represent the true asymptotic behaviour of alpha is derived. A second theorem considers the correlation functions. Discrepiancies between the theorems result in a solution that ''is regarded as a catastrophe'' in renormalization group theory. A lesson is drawn: To choose a good block spin in a renormalization group procedure, know what the low lying excitations of the theory are, to avoid integrating some of them by mischief

  7. Observation of the a3Σu+-Χ1Σg+ system of calcium dimer

    International Nuclear Information System (INIS)

    Gondal, M.A.; Khan, M.A.; Rais, M.H.

    1998-01-01

    The authors report the observation of collision-induced spectra of calcium dimer in the 680-692 nm region. The spectra were recorded after resonant laser excitation of 4s4p 3 P 1 state of atomic calcium. Here the upper state a 3 Σ u + is populated through collisions. The same spectra were reproduced in a low-current glow discharge in calcium vapor. The assignment of the observed spectral lines was carried out by applying the Dunham-type analysis and the spectra were assigned to the a 3 Σ u + -Χ 1 Σ g + transition of Ca 2 . The existence of a a 3 Σ u + state with v 00 =13850±1 cm -1 and ω e ∼37.6 cm -1 is confirmed

  8. Resolving taxonmic discrepancies: Role of Electronic Catalogues of Known Organisms

    Directory of Open Access Journals (Sweden)

    Vishwas Chavan

    2005-01-01

    Full Text Available There is a disparity in availability of nomenclature change literature to the taxonomists of the developing world and availability of taxonomic papers published by developing world scientists to their counterparts in developed part of the globe. This has resulted in several discrepancies in the naming of organisms. Development of electronic catalogues of names of known organisms would help in pointing out these issues. We have attempted to highlight a few of such discrepancies found while developing IndFauna, an electronic catalogue of known Indian fauna and comparing it with existing global and regional databases.Full Text: PDF

  9. Genome-wide DNA methylation profiling identifies ALDH1A3 promoter methylation as a prognostic predictor in G-CIMP- primary glioblastoma.

    Science.gov (United States)

    Zhang, Wei; Yan, Wei; You, Gan; Bao, Zhaoshi; Wang, Yongzhi; Liu, Yanwei; You, Yongping; Jiang, Tao

    2013-01-01

    To date, the aberrations in the DNA methylation patterns that are associated with different prognoses of G-CIMP- primary GBMs remain to be elucidated. Here, DNA methylation profiling of primary GBM tissues from 13 long-term survivors (LTS; overall survival ⩾18months) and 20 short-term survivors (STS; overall survival ⩽9months) was performed. Then G-CIMP+ samples were excluded. The differentially expressed CpG loci were identified between residual 18 STS and 9 LTS G-CIMP- samples. Methylation levels of 11 CpG loci (10genes) were statistically significantly lower, and 43 CpG loci (40genes) were statistically significantly higher in the tumor tissues of LTS than those of STS G-CIMP- samples (PCIMP- samples, 3 CpG loci localized in the promoter of ALDH1A3. Furthermore, using an independent validation cohort containing 37 primary GBM samples without IDH1 mutation and MGMT promoter methylation, the hypermethylation status of ALDH1A3 promoter predicted a better prognosis with an accompanied low expression of ALDH1A3 protein. Taken together, our results defined prognosis-related methylation signatures systematically for the first time in G-CIMP- primary GBMs. ALDH1A3 promoter methylation conferred a favorable prognosis in G-CIMP- primary GBMs. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  10. Establishing elements of a synthetic biology platform for Vaccinia virus production: BioBrick™ design, serum-free virus production and microcarrier-based cultivation of CV-1 cells.

    Science.gov (United States)

    Liu, Shuchang; Ruban, Ludmila; Wang, Yaohe; Zhou, Yuhong; Nesbeth, Darren N

    2017-02-01

    Vaccinia virus (VACV) is an established vector for vaccination and is beginning to prove effective as an oncolytic agent. Industrial production of VACV stands to benefit in future from advances made by synthetic biology in genome engineering and standardisation. The CV-1 cell line can be used for VACV propagation and has been used extensively with the CRISPR/Cas9 system for making precise edits of the VACV genome. Here we take first steps toward establishing a scalable synthetic biology platform for VACV production with CV-1 cells featuring standardised biological tools and serum free cell cultivation. We propose a new BioBrick™ plasmid backbone format for inserting transgenes into VACV. We then test the performance of CV-1 cells in propagation of a conventional recombinant Lister strain VACV, VACVL-15 RFP, in a serum-free process. CV-1 cells grown in 5% foetal bovine serum (FBS) Dulbecco's Modified Eagle Medium (DMEM) were adapted to growth in OptiPRO and VP-SFM brands of serum-free media. Specific growth rates of 0.047 h -1 and 0.044 h -1 were observed for cells adapted to OptiPRO and VP-SFM respectively, compared to 0.035 h -1 in 5% FBS DMEM. Cells adapted to OptiPRO and to 5% FBS DMEM achieved recovery ratios of over 96%, an indication of their robustness to cryopreservation. Cells adapted to VP-SFM showed a recovery ratio of 82%. Virus productivity in static culture, measured as plaque forming units (PFU) per propagator cell, was 75 PFU/cell for cells in 5% FBS DMEM. VP-SFM and OptiPRO adaptation increased VACV production to 150 PFU/cell and 350 PFU/cell respectively. Boosted PFU/cell from OptiPRO-adapted cells persisted when 5% FBS DMEM or OptiPRO medium was observed during the infection step and when titre was measured using cells adapted to 5% FBS DMEM or OptiPRO medium. Finally, OptiPRO-adapted CV-1 cells were successfully cultivated using Cytodex-1 microcarriers to inform future scale up studies.

  11. Establishing elements of a synthetic biology platform for Vaccinia virus production: BioBrick™ design, serum-free virus production and microcarrier-based cultivation of CV-1 cells

    Directory of Open Access Journals (Sweden)

    Shuchang Liu

    2017-02-01

    Full Text Available Vaccinia virus (VACV is an established vector for vaccination and is beginning to prove effective as an oncolytic agent. Industrial production of VACV stands to benefit in future from advances made by synthetic biology in genome engineering and standardisation. The CV-1 cell line can be used for VACV propagation and has been used extensively with the CRISPR/Cas9 system for making precise edits of the VACV genome. Here we take first steps toward establishing a scalable synthetic biology platform for VACV production with CV-1 cells featuring standardised biological tools and serum free cell cultivation. We propose a new BioBrick™ plasmid backbone format for inserting transgenes into VACV. We then test the performance of CV-1 cells in propagation of a conventional recombinant Lister strain VACV, VACVL-15 RFP, in a serum-free process. CV-1 cells grown in 5% foetal bovine serum (FBS Dulbecco’s Modified Eagle Medium (DMEM were adapted to growth in OptiPRO and VP-SFM brands of serum-free media. Specific growth rates of 0.047 h−1 and 0.044 h−1 were observed for cells adapted to OptiPRO and VP-SFM respectively, compared to 0.035 h−1 in 5% FBS DMEM. Cells adapted to OptiPRO and to 5% FBS DMEM achieved recovery ratios of over 96%, an indication of their robustness to cryopreservation. Cells adapted to VP-SFM showed a recovery ratio of 82%. Virus productivity in static culture, measured as plaque forming units (PFU per propagator cell, was 75 PFU/cell for cells in 5% FBS DMEM. VP-SFM and OptiPRO adaptation increased VACV production to 150 PFU/cell and 350 PFU/cell respectively. Boosted PFU/cell from OptiPRO-adapted cells persisted when 5% FBS DMEM or OptiPRO medium was observed during the infection step and when titre was measured using cells adapted to 5% FBS DMEM or OptiPRO medium. Finally, OptiPRO-adapted CV-1 cells were successfully cultivated using Cytodex-1 microcarriers to inform future scale up studies.

  12. Cytokinetically quiescent (G0/G1) human multiple myeloma cells are susceptible to simultaneous inhibition of Chk1 and MEK1/2.

    Science.gov (United States)

    Pei, Xin-Yan; Dai, Yun; Youssefian, Leena E; Chen, Shuang; Bodie, Wesley W; Takabatake, Yukie; Felthousen, Jessica; Almenara, Jorge A; Kramer, Lora B; Dent, Paul; Grant, Steven

    2011-11-10

    Effects of Chk1 and MEK1/2 inhibition were investigated in cytokinetically quiescent multiple myeloma (MM) and primary CD138(+) cells. Coexposure to the Chk1 and MEK1/2 inhibitors AZD7762 and selumetinib (AZD6244) robustly induced apoptosis in various MM cells and CD138(+) primary samples, but spared normal CD138(-) and CD34(+) cells. Furthermore, Chk1/MEK1/2 inhibitor treatment of asynchronized cells induced G(0)/G(1) arrest and increased apoptosis in all cell-cycle phases, including G(0)/G(1). To determine whether this regimen is active against quiescent G(0)/G(1) MM cells, cells were cultured in low-serum medium to enrich the G(0)/G(1) population. G(0)/G(1)-enriched cells exhibited diminished sensitivity to conventional agents (eg, Taxol and VP-16) but significantly increased susceptibility to Chk1 ± MEK1/2 inhibitors or Chk1 shRNA knock-down. These events were associated with increased γH2A.X expression/foci formation and Bim up-regulation, whereas Bim shRNA knock-down markedly attenuated lethality. Immunofluorescent analysis of G(0)/G(1)-enriched or primary MM cells demonstrated colocalization of activated caspase-3 and the quiescent (G(0)) marker statin, a nuclear envelope protein. Finally, Chk1/MEK1/2 inhibition increased cell death in the Hoechst-positive (Hst(+)), low pyronin Y (PY)-staining (2N Hst(+)/PY(-)) G(0) population and in sorted small side-population (SSP) MM cells. These findings provide evidence that cytokinetically quiescent MM cells are highly susceptible to simultaneous Chk1 and MEK1/2 inhibition.

  13. Catalogue Creation for Space Situational Awareness with Optical Sensors

    Science.gov (United States)

    Hobson, T.; Clarkson, I.; Bessell, T.; Rutten, M.; Gordon, N.; Moretti, N.; Morreale, B.

    2016-09-01

    In order to safeguard the continued use of space-based technologies, effective monitoring and tracking of man-made resident space objects (RSOs) is paramount. The diverse characteristics, behaviours and trajectories of RSOs make space surveillance a challenging application of the discipline that is tracking and surveillance. When surveillance systems are faced with non-canonical scenarios, it is common for human operators to intervene while researchers adapt and extend traditional tracking techniques in search of a solution. A complementary strategy for improving the robustness of space surveillance systems is to place greater emphasis on the anticipation of uncertainty. Namely, give the system the intelligence necessary to autonomously react to unforeseen events and to intelligently and appropriately act on tenuous information rather than discard it. In this paper we build from our 2015 campaign and describe the progression of a low-cost intelligent space surveillance system capable of autonomously cataloguing and maintaining track of RSOs. It currently exploits robotic electro-optical sensors, high-fidelity state-estimation and propagation as well as constrained initial orbit determination (IOD) to intelligently and adaptively manage its sensors in order to maintain an accurate catalogue of RSOs. In a step towards fully autonomous cataloguing, the system has been tasked with maintaining surveillance of a portion of the geosynchronous (GEO) belt. Using a combination of survey and track-refinement modes, the system is capable of maintaining a track of known RSOs and initiating tracks on previously unknown objects. Uniquely, due to the use of high-fidelity representations of a target's state uncertainty, as few as two images of previously unknown RSOs may be used to subsequently initiate autonomous search and reacquisition. To achieve this capability, particularly within the congested environment of the GEO-belt, we use a constrained admissible region (CAR) to

  14. Tumor Necrosis Factor (TNF -308G>A, Nitric Oxide Synthase 3 (NOS3 +894G>T Polymorphisms and Migraine Risk: A Meta-Analysis.

    Directory of Open Access Journals (Sweden)

    Min Chen

    Full Text Available Conflicting data have been reported on the association between tumor necrosis factor (TNF -308G>A and nitric oxide synthase 3 (NOS3 +894G>T polymorphisms and migraine. We performed a meta-analysis of case-control studies to evaluate whether the TNF -308G>A and NOS3 +894G>T polymorphisms confer genetic susceptibility to migraine.We performed an updated meta-analysis for TNF -308G>A and a meta-analysis for NOS3 +894G>T based on studies published up to July 2014. We calculated study specific odds ratios (OR and 95% confidence intervals (95% CI assuming allele contrast, dominant model, recessive model, and co-dominant model as pooled effect estimates.Eleven studies in 6682 migraineurs and 22591 controls for TNF -308G>A and six studies in 1055 migraineurs and 877 controls for NOS3 +894G>T were included in the analysis. Neither indicated overall associations between gene polymorphisms and migraine risk. Subgroup analyses suggested that the "A" allele of the TNF -308G>A variant increases the risk of migraine among non-Caucasians (dominant model: pooled OR = 1.82; 95% CI 1.15 - 2.87. The risk of migraine with aura (MA was increased among both Caucasians and non-Caucasians. Subgroup analyses suggested that the "T" allele of the NOS3 +894G>T variant increases the risk of migraine among non-Caucasians (co-dominant model: pooled OR = 2.10; 95% CI 1.14 - 3.88.Our findings appear to support the hypothesis that the TNF -308G>A polymorphism may act as a genetic susceptibility factor for migraine among non-Caucasians and that the NOS3 +894G>T polymorphism may modulate the risk of migraine among non-Caucasians.

  15. Multifractal Omori law for earthquake triggering: new tests on the California, Japan and worldwide catalogues

    Science.gov (United States)

    Ouillon, G.; Sornette, D.; Ribeiro, E.

    2009-07-01

    The Multifractal Stress-Activated model is a statistical model of triggered seismicity based on mechanical and thermodynamic principles. It predicts that, above a triggering magnitude cut-off M0, the exponent p of the Omori law for the time decay of the rate of aftershocks is a linear increasing function p(M) = a0M + b0 of the main shock magnitude M. We previously reported empirical support for this prediction, using the Southern California Earthquake Center (SCEC) catalogue. Here, we confirm this observation using an updated, longer version of the same catalogue, as well as new methods to estimate p. One of this methods is the newly defined Scaling Function Analysis (SFA), adapted from the wavelet transform. This method is able to measure a mathematical singularity (hence a p-value), erasing the possible regular part of a time-series. The SFA also proves particularly efficient to reveal the coexistence and superposition of several types of relaxation laws (typical Omori sequences and short-lived swarms sequences) which can be mixed within the same catalogue. Another new method consists in monitoring the largest aftershock magnitude observed in successive time intervals, and thus shortcuts the problem of missing events with small magnitudes in aftershock catalogues. The same methods are used on data from the worldwide Harvard Centroid Moment Tensor (CMT) catalogue and show results compatible with those of Southern California. For the Japan Meteorological Agency (JMA) catalogue, we still observe a linear dependence of p on M, but with a smaller slope. The SFA shows however that results for this catalogue may be biased by numerous swarm sequences, despite our efforts to remove them before the analysis.

  16. NWA10758: A New CV3 Chondrite Bearing a Giant CAI with Hibonite-Rich Wark-Lovering Rim

    Science.gov (United States)

    Ross, D. K.; Simon, J. I.; Zolensky, M.

    2017-01-01

    Northwest Africa (NWA) 10758 is a newly identified carbonaceous chondrite that is a Bali-like oxidized CV3. The large Ca-Al rich inclusion (CAI) in this sample is approx. 2.4 x 1.4 cm. The CAI is transitional in composition between type A and type B, with interior mineralogy dominated by melilite, plus less abundant spinel and Al-Ti rich diopside, and only very minor anorthite (Fig. 1A). This CAI is largely free of secondary alteration in the exposed section we examined, with almost no nepheline, sodalite or Ca-Fe silicates. The Wark-Lovering (WL) rim on this CAI is dominated by hibonite, with lower abundances of spinel and perovskite, and with hibonite locally overlain by melilite plus perovskite (as in Fig. 1B). Note that the example shown in 1B is exceptional. Around most of the CAI, hibonite + spinel + perovskite form the WL rim, without overlying melilite. The WL rim can be unusually thick, ranging from approx. 20 microns up to approx. 150 microns. A well-developed, stratified accretionary rim infills embayments of the CAI, and thins over protuberances in the convoluted CAI surface.

  17. Sorption of europium (3) by polymer sorbents with grafted heterocyclic nitrogen-containing groupings

    International Nuclear Information System (INIS)

    Bel'tyukova, S.V.; Kravchenko, T.B.; Balamtsarashvili, G.M.; Roska, A.S.

    1990-01-01

    On polymer sorbents (copolymer of styrene-divinylbenzene) with grafted heterocyclic nitrogen-containing functional groupings of tetrazole, triazole and imidazole (sorbents 1,2,3, respectively). It is stated that europium sorption takes place from neutral solutions in presence of organic solvents. Luminescent properties of europium on sorbent are used to develope methods of its determination in high purity lanthanide and yttrium oxides. Europium determination limits consist 7.5·10 -5 μg/ml on 1 and 3 sorbents and 1.5·10 -4 μg/ml on sorbent 2, S p value is 0.089 and 0.075, respectivaly

  18. Supplementary data Fig. S1 Fig. S1. FE-SEM images of the ...

    Indian Academy of Sciences (India)

    微软用户

    Fig. S3. Cycling behavior of V2O5 nanomaterials recorded by CV at 20 mV·s-1 scan rate. Page 4. 4. Fig. S4. Fig. S4. Cycling behavior of V2O5 nanomaterials electrodes of galvanostatic charge and discharge profiles recorded by GCD at a current density of 1g-1. Page 5. 5. Fig. S5. Fig. S5. Cycling behavior of V2O5 ...

  19. Incidência de fumonisina B1, aflatoxinas B1, B2, G1 e G2, ocratoxina A e zearalenona em produtos de milho Occurrence of fumonisin B1, aflatoxins B1, B2, G1, and G2, ochratoxin A and zearalenone in corn products

    Directory of Open Access Journals (Sweden)

    Luciane Mie Kawashima

    2006-09-01

    Full Text Available Levantamentos de ocorrência de micotoxinas em alimentos foram realizados nas últimas duas décadas nas regiões Sudeste e Sul do Brasil. Levantamentos em alimentos comercializados em outras regiões têm-se limitado a aflatoxinas em amendoim e castanhas do Brasil. O presente trabalho pesquisou a presença de fumonisina B1, aflatoxinas B1, B2, G1 e G2, ocratoxina A e zearalenona em 74 amostras de produtos a base de milho adquiridas no comércio da cidade de Recife, PE, durante o período de 1999 a 2001. Fumonisina B1 foi determinada por cromatografia líquida de alta eficiência com detecção por fluorescência e as demais toxinas foram determinadas por cromatografia em camada delgada. Fumonisina B1 foi encontrada em 94,6% das amostras em concentrações variando de 20 a 8600 µg/kg. Apenas 5 amostras continham aflatoxina B1 e o teor máximo encontrado foi 20 µg/kg. Duas amostras ultrapassaram o limite de 20 µg/kg para a somatória das aflatoxinas B1, B2, G1 e G2 (farinha de milho pré-cozida com 21,5 µg/kg e quirera (xerém com 23,3 µg/kg. As aflatoxinas G1 e G2, ocratoxina A e zearalenona não foram detectadas em nenhuma das amostras. Todas as amostras contaminadas com aflatoxinas também apresentaram fumonisina B1.Research concerning the presence of mycotoxin in food has been conducted in the Southwest and South regions of Brazil over the last two decades. Research in other regions has been limited to aflatoxin in peanuts and Brazil nuts. The aim of this work is to study the presence of fumonisin B1, aflatoxins B1, B2, G1, and G2, ochratoxin A and zearalenone in 74 samples of corn products acquired in shops and food markets in the city of Recife (PE from 1999 to 2001. Fumonisin B1 was determined by high performance liquid chromatography and fluorescence was detected. The other toxins were determined by thin layer chromatography. Fumonisin B1 was found in 94.6% of the samples in levels from 20 to 8600 µg/kg. Only 5 samples contained

  20. A Monte Carlo Approach to Modeling the Breakup of the Space Launch System EM-1 Core Stage with an Integrated Blast and Fragment Catalogue

    Science.gov (United States)

    Richardson, Erin; Hays, M. J.; Blackwood, J. M.; Skinner, T.

    2014-01-01

    The Liquid Propellant Fragment Overpressure Acceleration Model (L-FOAM) is a tool developed by Bangham Engineering Incorporated (BEi) that produces a representative debris cloud from an exploding liquid-propellant launch vehicle. Here it is applied to the Core Stage (CS) of the National Aeronautics and Space Administration (NASA) Space Launch System (SLS launch vehicle). A combination of Probability Density Functions (PDF) based on empirical data from rocket accidents and applicable tests, as well as SLS specific geometry are combined in a MATLAB script to create unique fragment catalogues each time L-FOAM is run-tailored for a Monte Carlo approach for risk analysis. By accelerating the debris catalogue with the BEi blast model for liquid hydrogen / liquid oxygen explosions, the result is a fully integrated code that models the destruction of the CS at a given point in its trajectory and generates hundreds of individual fragment catalogues with initial imparted velocities. The BEi blast model provides the blast size (radius) and strength (overpressure) as probabilities based on empirical data and anchored with analytical work. The coupling of the L-FOAM catalogue with the BEi blast model is validated with a simulation of the Project PYRO S-IV destruct test. When running a Monte Carlo simulation, L-FOAM can accelerate all catalogues with the same blast (mean blast, 2 s blast, etc.), or vary the blast size and strength based on their respective probabilities. L-FOAM then propagates these fragments until impact with the earth. Results from L-FOAM include a description of each fragment (dimensions, weight, ballistic coefficient, type and initial location on the rocket), imparted velocity from the blast, and impact data depending on user desired application. LFOAM application is for both near-field (fragment impact to escaping crew capsule) and far-field (fragment ground impact footprint) safety considerations. The user is thus able to use statistics from a Monte Carlo