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Sample records for groundhogs marmota monax

  1. 2011 Groundhog Reservoir Bathymetric Contours

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The U.S. Geological Survey performed a bathymetric survey of Groundhog Reservoir using a man-operated boat-mounted multibeam echo sounder integrated with a global...

  2. "Groundhog Day, Deja Vu," and the Myth of the Eternal Recurrence.

    Science.gov (United States)

    Voeltz, Richard A.

    1998-01-01

    Reveals that through the use of the movie "Groundhog Day," students in humanities courses can grasp Friedrich Nietzsche's myth of eternal recurrence; the myth addresses the question of what if everything that occurred in one's life occurred again just as it happened before. Discusses the similarities between Nietzsche's myth and the…

  3. "Groundhog Day, Deja Vu," and the Myth of the Eternal Recurrence.

    Science.gov (United States)

    Voeltz, Richard A.

    1998-01-01

    Reveals that through the use of the movie "Groundhog Day," students in humanities courses can grasp Friedrich Nietzsche's myth of eternal recurrence; the myth addresses the question of what if everything that occurred in one's life occurred again just as it happened before. Discusses the similarities between Nietzsche's myth and the…

  4. Alimentazione di Marmota marmota in praterie altimontane delle dolomiti bellunesi

    Directory of Open Access Journals (Sweden)

    Alessandro Rudatis

    2006-03-01

    Full Text Available Abstract The diet of Marmota marmota in the mountain prairie of south-eastern Italian Alps. Diet composition of two family groups of alpine marmots was investigated in two areas of the Agordino’s Dolomites (Italian Alps in June-September 2001, by means of microscopic analysis of faeces and of direct observation of feeding activity. During the whole period of activity, a high consume of Angiosperms was confirmed, especially plants in flower; among them the “graminoids” seemed to play an important role only during the initial part of the active period. Generally vegetative parts predominated over flowers. The ingestion of animal preys was not confirmed by the analysis of droppings. Comparing diet composition of the two groups, Graminaceae (Poa, Phleum, Compositae (Achillea, Cyperaceae/Juncaceae, Leguminosae (Anthyllis, Rosaceae, and Labiatae (Prunella, Stachys formed the bulk of marmot diet in the study areas. Diet showed low diversity considering the abundance of plant species in the surrounding environment. Food resources were probably used in relation to their easy digestibility, with a high content in proteins, sugar and water. The knowledge of vegetation features in relation to marmot trophic habits can represent a useful tool for the management of this species. Riassunto Il regime alimentare di due gruppi di Marmotta alpina è stato studiato in giugno-settembre 2001 in due aree delle Dolomiti agordine (SE Italia, attraverso l’analisi microscopica delle feci e l’osservazione diretta dell’attività alimentare. Durante tutto il periodo di attività si è notato un forte consumo di Angiosperme, specialmente piante a fiore, mentre le ”graminoidi” sembra giochino un ruolo importante all’inizio della stagione. In generale le parti vegetali predominano sui fiori. L’ingestione di prede animali non è stata

  5. Seasonal 4-year investigation into the role of the alpine marmot (Marmota marmota) as a carrier of zoophilic dermatophytes.

    Science.gov (United States)

    Gallo, M G; Lanfranchi, P; Poglayen, G; Calderola, S; Menzano, A; Ferroglio, E; Peano, A

    2005-06-01

    Two hundred and six samples of alpine marmot (Mamota marmota) hair (148 from adults and 58 from young subjects), 102 soil samples from the entrances to the burrows of the above individuals and 20 control specimens (obtained from adjoining areas away from the burrow systems where the rodents are not usually present) were examined from May 1994 to September 1997. Seventy-five isolates belonging to six species of dermatophytes were found in 69 of the 206 hair samples examined (33.5%). Two species were zoophilic, Microsporum canis (7.8%) and Trichophyton mentagrophytes (11.2.%), and four geophilic, Microsporum cookei (2%), M. gypseum (5.8%), Trichophyton ajelloi (3.9%) and T. terrestre (5.8%). The prevalence of each species in the hair samples did not change significantly according to year, season (chi-squared test [limit significance: P 0.05] both in year and in season comparison) or age/sex (adult versus juvenile: P=0.1; male versus female: P=0.8) of the marmot. Twenty-three of the 102 soil samples (22.5%) were positive for dermatophytes found in the hair of marmots from the same burrow systems. Five of the 20 control soil samples (25%) were positive for dermatophytes. One isolate of M. gypseum, three of T. terrestre and one of T. mentagrophytes were obtained. Compared with other free-ranging rodent hosts studied in Europe, this mycoflora is characterized by the presence and relatively high prevalence of M. canis, frequently reported in symptomatic and asymptomatic cats, dogs and fur animals. M. canis has not been isolated in other rodents in the wild. However, it has recently been reported in asymptomatic foxes (Vulpes vulpes) from northern Italy. The close link between V vulpes and M. marmota, with the former representing the most important mammal predator of the latter in the Alps (only a fraction of the predator's attacks result in the death of the rodent) may have favoured the adaptation of M. canis to this rodent host. The stable character of the M. canis

  6. Cloning, Expression and Polyclonal Antibody Preparation of the Asialoglycoprotein Receptor of Marmota Himalayan

    Institute of Scientific and Technical Information of China (English)

    YANG Yan; HUANG Huang; ZHANG Zhenghua; WANG Baoju; TIAN Yongjun; LU Mengji; YANG Dongliang

    2007-01-01

    The objective of this study is to express the carbohydrate recognition domain (CRD) of the asialoglycoprotein receptor (ASGPR) H1 and H2 subunits of Marmota himalayan in vitro, and develop polyclonal antibodies against the recombinant proteins. RT-PCR was used to amplify ASGPR CRDH1 and CRDH2 from the liver tissue of Marmota himalayan. The products of amplification were subcloned into prokaryotic expression vector pRSET-B, and expressed in E. coli BL21(DE3)plysS. The recombinant proteins were purified using Ni-NTA spin column. The purified proteins were inoculated into BALB/c mice to develop polyclonal antibodies. The sensitivity and specificity of antibodies were evaluated by enzyme-linked immunosorbent assay (ELISA), Western blotting and immunohistochemical staining (IHC). The polyclonal antibodies showed high sensitivity and specificity against both denaturated and native ASGPR proteins. We successfully amplified and expressed the ASGPR CRDs of Marmota himalayan. The nucleic sequences of ASGPR CRDH1 and CRDH2 of Marmota himalayan have been submitted to Genbank and the sequence ID are DQ 845465 and DQ845466, respectively. The proteins and antibodies prepared can be used for targeting gene therapy in a new animal model-Marmota himalayan-for the research of infectious diseases of hepatitis viruses and liver cancer treatment.

  7. Helicobacter marmotae and novel Helicobacter and Campylobacter species isolated from the livers and intestines of prairie dogs

    Science.gov (United States)

    Beisele, Maike; Shen, Zeli; Parry, Nicola; Mobley, Melissa; Taylor, Nancy S.; Buckley, Ellen; Abedin, Mohammad Z.; Dewhirst, Floyd E.

    2011-01-01

    Prairie dogs (Cynomys ludovicianus) are used to study the aetiology and prevention of gallstones because of the similarities of prairie dog and human bile gallstone composition. Epidemiological and experimental studies have suggested a connection between infection with Helicobacter species and cholesterol cholelithiasis, cholecystis and gallbladder cancer. Ten of the 34 prairie dogs in this study had positive Helicobacter species identified by PCR using Helicobacter genus-specific primers. Ten of 34 prairie dogs had positive Campylobacter species identified in the intestine by PCR with Campylobacter genus-specific primers. Six Helicobacter sp. isolates and three Campylobacter sp. isolates were identified taxonomically by 16S rRNA gene analysis. The prairie dog helicobacters fell into three clusters adjacent to Helicobacter marmotae. On the basis of 16S rRNA gene sequence analysis, three strains in two adjacent clusters were included in the species H. marmotae. Three strains were only 97.1 % similar to the sequence of H. marmotae and can be considered a novel species with the provisional designation Helicobacter sp. Prairie Dog 3. The prairie dog campylobacters formed a single novel cluster and represent a novel Campylobacter sp. with the provisional designation Campylobacter sp. Prairie Dog. They branched with Campylobacter cuniculorum at 96.3 % similarity and had the greatest sequence similarity to Campylobacter helveticus at 97.1 % similarity. Whether H. marmotae or the novel Helicobacter sp. and Campylobacter sp. identified in prairie dogs play a role in cholesterol gallstones or hepatobiliary disease requires further studies. PMID:21546560

  8. Stenochlaena palustris aqueous extract reduces hepatic peroxidative stress in Marmota caligata with induced fever

    Directory of Open Access Journals (Sweden)

    Adenan

    2010-12-01

    Full Text Available The kelakai fern (Stenochlaena palustris contains bioactive substances, such as flavonoids, steroids, and alkaloids. The kelakai is used by the Kenyah Dayak communities for the treatment of anemia, fever, and cutaneous disorders. Fever is increased temperature regulation of the body, which process indirectly increases the production of peroxides, leading to peroxidative stress. The aim of this research study was to evaluate the influence of an aqueous extract of the kelakai fern on peroxidative stress in the hoary marmot (Marmota caligata with experimentally-induced fever. This was a true experimental study, with post test-only and control group design, involving 6 groups, each made up of 4 animals. Peroxide concentration was measured by a modification of the FOX2 method and peroxidase activity by the Kanehira method. The kelakai extract was administered to the animals by gavage at weight-adjusted dosages between 7.75 x 10-4 mg/kg body weight to 1.24 x 10-2 mg/kg body weight. Data were analyzed using singe linear regression test. The results showed that kelakai extract dose significantly reduced the peroxide levels, regression equation with the Y = 2.513-106.03 X (R2 = 0.8057, indicating that 80.5% variation of peroxide levels is predicted by the kelakai extract dose. From the results we conclude that kelakai aqueous extract decreases peroxide levels in hoary marmots with experimentally-induced fever.

  9. Elevation and vegetation determine Cryptosporidium oocyst shedding by yellow-bellied marmots (Marmota flaviventris in the Sierra Nevada Mountains

    Directory of Open Access Journals (Sweden)

    Diego Montecino-Latorre

    2015-08-01

    Full Text Available Wildlife are increasingly recognized as important biological reservoirs of zoonotic species of Cryptosporidium that might contaminate water and cause human exposure to this protozoal parasite. The habitat range of the yellow-bellied marmot (Marmota flaviventris overlaps extensively with the watershed boundaries of municipal water supplies for California communities along the foothills of the Sierra Nevada. We conducted a cross-sectional epidemiological study to estimate the fecal shedding of Cryptosporidium oocysts by yellow-bellied marmots and to quantify the environmental loading rate and determine risk factors for Cryptosporidium fecal shedding in this montane wildlife species. The observed proportion of Cryptosporidium positive fecal samples was 14.7% (33/224, positive number relative to total number samples and the environmental loading rate was estimated to be 10,693 oocysts animal-1 day-1. Fecal shedding was associated with the elevation and vegetation status of their habitat. Based on a portion of the 18s rRNA gene sequence of 2 isolates, the Cryptosporidium found in Marmota flaviventris were 99.88%–100% match to multiple isolates of C. parvum in the GenBank.

  10. Pancreatic A and B cell stimulation in euthermic and hibernating marmots (Marmota flaviventris): effects of glucose and arginine administration.

    Science.gov (United States)

    Florant, G L; Hoo-Paris, R; Castex, C; Bauman, W A; Sutter, B C

    1986-01-01

    In euthermic and hibernating marmots (Marmota flaviventris), the pancreatic A and B cells respond in the appropriate secretory manner to glucose or arginine injection. Although reduced, this response, is clearly present in hibernating marmots. When glucose is administered to euthermic or hibernating marmots, plasma insulin concentrations rise and glucagon levels fall. While similar results are obtained in hibernation, the time period of the response is much longer due to the slowing of temperature dependent metabolic processes. Injection of L-arginine stimulates an increase in plasma glucose, insulin, and glucagon as expected. Measurements of plasma glucose, insulin, and glucagon under basal conditions, suggest that there are no significant differences between any phase of hibernation (eg. entrance, deep hibernation, arousal) and euthermia. These results provide indirect evidence that the pancreatic A and B cells of hibernating marmots continue to function in order to help regulate plasma glucose concentration.

  11. Fatal combined infection with canine distemper virus and orthopoxvirus in a group of Asian marmots (Marmota caudata).

    Science.gov (United States)

    Origgi, F C; Sattler, U; Pilo, P; Waldvogel, A S

    2013-09-01

    A fatal combined infection with canine distemper virus (CDV) and orthopoxvirus (OPXV) in Asian marmots (Marmota caudata) is reported in this article. A total of 7 Asian marmots from a small zoological garden in Switzerland were found dead in hibernation during a routine check in the winter of 2011. The marmots died in February 2011. No clinical signs of disease were observed at any time. The viruses were detected in all individuals for which the tissues were available (n = 3). Detection of the viruses was performed by reverse transcription polymerase chain reaction. The most consistent gross lesion was a neck and thorax edema. A necrotizing pharyngitis and a multifocal necrotizing pneumonia were observed histologically. Numerous large intracytoplasmic eosinophilic inclusions were seen in the epithelial cells of the pharynx, of the airways, and in the skin keratinocytes. Brain lesions were limited to mild multifocal gliosis. Phylogenetic analysis revealed that the marmot CDV strain was closely related to the clusters of CDVs detected in Switzerland in wild carnivores during a local outbreak in 2002 and the 2009-2010 nationwide epidemic, suggesting a spillover of this virus from wildlife. The OPXV was most closely related to a strain of cowpoxvirus, a poxvirus species considered endemic in Europe. This is the first reported instance of CDV infection in a rodent species and of a combined CDV and OPXV infection.

  12. Environmental Assessment: T-10 Hush House Tinker Air Force Base, Oklahoma

    Science.gov (United States)

    2008-07-01

    Notropis girardi Arkansas River Shiner T T Mammals Marmota monax Woodchuck SS2 Reptiles Phrynosoma cornutum Texas Horned Lizard SS2...and Soldier Creeks that are located on Tinker AFB (Tinker AFB 2002). Some ponds on the facility have been stocked with fish including catfish

  13. Environmental Assessment: Construction of Air Traffic Control Tower Tinker Air Force Base, Oklahoma

    Science.gov (United States)

    2009-03-01

    Species of Oklahoma County (Continued) Scientific Name Common Name State Status1 Federal Status1 Mammals Marmota monax Woodchuck SS2 Reptiles...2002a). Some ponds on the facility have been stocked with fish including catfish (Ictalurus punctatus), largemouth bass (Micropterus salmoides

  14. 野生白化喜马拉雅旱獭体内寄生虫检测与控制%Survey on the internal parasites infection and control technique in albinism Marmota himalayana

    Institute of Scientific and Technical Information of China (English)

    陶元清

    2015-01-01

    Objective To investigate the internal parasites infection in albino Marmota himalayan,and to provide a basis for seting up the quality standard of Marmota himalayana.Methods 21 wild albinism and 30 wild nomal Marmota himalayana from the same origin were detected by method as intestinal parasites in stool examination and serological testing, toxoplasma gondii and echinococcosis parasite infections of each animal, then detected the internal parasites and eggs under platoscope and microscope.Results The natural infectious rate of the roundworm in wild albinism and nomal Marmota Himalayana were respectively 71.4% (15 /21) and 66.7% (20 /30), using the exact probability method of inspection, there was no significant difference in the roundworm infection rate between two groups marmota; antibody test results of Serum toxoplasma gondii and Echinoocosis were negative.Application of albendazole and Ivermectin injection drug expelling and purification, effect to be trusted.Conclusions Monitoring results and the cure method can be used as an albino Himalayan marmot displacement experiment of animal parasite quality monitoring index and purification method.%目的:调查白化旱獭重要病原体的自然感染状况,为建立白化旱獭寄生虫学质量控制标准提供依据。方法对21只野生的白化旱獭和30只正常毛色旱獭采用粪便检查法和血清学方法检测了蠕虫、弓形体、棘球蚴等体内寄生虫感染情况。结果51只野生白化喜马拉雅旱獭和正常毛色旱獭检出蠕虫1种,弓形体和棘球蚴抗体检测结果均为阴性。应用阿苯达唑片剂和伊维菌素注射液进行了旱獭体内寄生虫驱虫和净化,效果良好。结论监测结果初步表明白化旱獭寄生虫学质量符合种群动物的寄生虫要求。

  15. Stable isotopes in yellow-bellied marmot (Marmota flaviventris) fossils reveal environmental stability in the late Quaternary of the Colorado Rocky Mountains

    Science.gov (United States)

    Reynard, Linda M.; Meltzer, David J.; Emslie, Steven D.; Tuross, Noreen

    2015-03-01

    High elevation plant and animal communities are considered extremely sensitive to environmental change. We investigated an exceptional fossil record of yellow-bellied marmot (Marmota flaviventris) specimens that was recovered from Cement Creek Cave (elev. 2860 m) and ranged in age from radiocarbon background circa 49.8 cal ka BP to ~ 1 cal ka BP. We coupled isotopic and radiocarbon measurements (δ18O, δD, δ15N, δ13C, and 14C) of bone collagen from individually-AMS dated specimens of marmots to assess ecological responses by this species to environmental change over time in a high elevation basin in the Rocky Mountains of southwestern Colorado, USA. We find little change in all four isotope ratios over time, demonstrating considerable environmental stability during periods when the marmots were present. The stable ecology and the apparent persistence of the small mammal community in the cave fauna throughout the late Quaternary are in marked contrast to the changes that occurred in the large mammal community, including local extirpation and extinction, at the end of the Pleistocene.

  16. Insights into the evolution of pathogenicity of Escherichia coli from genomic analysis of intestinal E. coli of Marmota himalayana in Qinghai–Tibet plateau of China

    Science.gov (United States)

    Lu, Shan; Jin, Dong; Wu, Shusheng; Yang, Jing; Lan, Ruiting; Bai, Xiangning; Liu, Sha; Meng, Qiong; Yuan, Xuejiao; Zhou, Juan; Pu, Ji; Chen, Qiang; Dai, Hang; Hu, Yuanyuan; Xiong, Yanwen; Ye, Changyun; Xu, Jianguo

    2016-01-01

    Escherichia coli is both of a widespread harmless gut commensal and a versatile pathogen of humans. Domestic animals are a well-known reservoir for pathogenic E. coli. However, studies of E. coli populations from wild animals that have been separated from human activities had been very limited. Here we obtained 580 isolates from intestinal contents of 116 wild Marmot Marmota himalayana from Qinghai–Tibet plateau, China, with five isolates per animal. We selected 125 (hereinafter referred to as strains) from the 580 isolates for genome sequencing, based on unique pulse field gel electrophoresis patterns and at least one isolate per animal. Whole genome sequence analysis revealed that all 125 strains carried at least one and the majority (79.2%) carried multiple virulence genes based on the analysis of 22 selected virulence genes. In particular, the majority of the strains carried virulence genes from different pathovars as potential 'hybrid pathogens'. The alleles of eight virulence genes from the Marmot E. coli were found to have diverged earlier than all known alleles from human and other animal E. coli. Phylogenetic analysis of the 125 Marmot E. coli genomes and 355 genomes selected from 1622 human and other E. coli strains identified two new phylogroups, G and H, both of which diverged earlier than the other phylogroups. Eight of the 12 well-known pathogenic E. coli lineages were found to share a most recent common ancestor with one or more Marmot E. coli strains. Our results suggested that the intestinal E. coli of the Marmots contained a diverse virulence gene pool and is potentially pathogenic to humans. These findings provided a new understanding of the evolutionary origin of pathogenic E. coli. PMID:27924811

  17. Insights into the evolution of pathogenicity of Escherichia coli from genomic analysis of intestinal E. coli of Marmota himalayana in Qinghai-Tibet plateau of China.

    Science.gov (United States)

    Lu, Shan; Jin, Dong; Wu, Shusheng; Yang, Jing; Lan, Ruiting; Bai, Xiangning; Liu, Sha; Meng, Qiong; Yuan, Xuejiao; Zhou, Juan; Pu, Ji; Chen, Qiang; Dai, Hang; Hu, Yuanyuan; Xiong, Yanwen; Ye, Changyun; Xu, Jianguo

    2016-12-07

    Escherichia coli is both of a widespread harmless gut commensal and a versatile pathogen of humans. Domestic animals are a well-known reservoir for pathogenic E. coli. However, studies of E. coli populations from wild animals that have been separated from human activities had been very limited. Here we obtained 580 isolates from intestinal contents of 116 wild Marmot Marmota himalayana from Qinghai-Tibet plateau, China, with five isolates per animal. We selected 125 (hereinafter referred to as strains) from the 580 isolates for genome sequencing, based on unique pulse field gel electrophoresis patterns and at least one isolate per animal. Whole genome sequence analysis revealed that all 125 strains carried at least one and the majority (79.2%) carried multiple virulence genes based on the analysis of 22 selected virulence genes. In particular, the majority of the strains carried virulence genes from different pathovars as potential 'hybrid pathogens'. The alleles of eight virulence genes from the Marmot E. coli were found to have diverged earlier than all known alleles from human and other animal E. coli. Phylogenetic analysis of the 125 Marmot E. coli genomes and 355 genomes selected from 1622 human and other E. coli strains identified two new phylogroups, G and H, both of which diverged earlier than the other phylogroups. Eight of the 12 well-known pathogenic E. coli lineages were found to share a most recent common ancestor with one or more Marmot E. coli strains. Our results suggested that the intestinal E. coli of the Marmots contained a diverse virulence gene pool and is potentially pathogenic to humans. These findings provided a new understanding of the evolutionary origin of pathogenic E. coli.

  18. The First Case of Familial Albinism Marmota himalayana from Qinghai Province%我国首例白化喜马拉雅旱獭家族的发现及其描述

    Institute of Scientific and Technical Information of China (English)

    陶元清; 汪元忠; 王虎; 郭庆

    2009-01-01

    喜马拉雅旱獭Marmota himalayana属啮齿目Rodentia松鼠科Sciuridae旱獭属Marmota,是大型地栖性啮齿动物,为青藏高原特有种。其正常体色为自鼻端经两眼眉问到两耳前方之间有似三角形的黑色毛区。眼黑色。嘴四周为黄白色、淡棕黄色或桔黄色,眼眶黑色,面部两颊到耳外侧基部呈黄褐色或淡棕黄色。耳壳呈淡棕黄色或深黄色。颈背和体背部同色,呈沙黄色、棕黄色或草黄色。毛基黑褐色,中段草黄色或浅黄色,毛尖黑色。背部至臀部黑色毛尖多显著,常形成不规则的黑色细斑纹。体侧黑色毛尖较少,故体侧较体背毛色稍浅。

  19. Beyond the Talking Groundhogs: Trends in Science Trade Books

    Science.gov (United States)

    Rearden, Kristin T.; Broemmel, Amy D.

    2008-01-01

    Resources for selecting high-quality elementary science trade books include lists exclusively for science and those that contain a broad spectrum of content foci such as the IRA's "Teachers' Choices" list. In this study, the genres and content areas of science-based "Teachers' Choices" books from the list's inception in 1988 through 2004 were…

  20. Groundhog Day: Expectation Management by Examining Warfare in the Early Twentieth Century Balkans

    Science.gov (United States)

    2007-06-15

    Serbian. 86 hern ict h s e le ayton Peace Accords, signed in December 1991 and the subsequ people ir to ere willing to burn the house or...Croats and Slovenes after World War I. On June 12th, the European Union recognized the new nation and the United States followed on June 15th.12 elt

  1. Lead in tissues of woodchucks fed crown vetch growing adjacent to a highway.

    Science.gov (United States)

    Young, R W; Ridgely, S L; Blue, J T; Bache, C A; Lisk, D J

    1986-01-01

    Woodchucks (Marmota monax) were fed crown vetch (Coronilla varia) growing along a major highway that was harvested in 1979, before unleaded gas was widely used, and again in 1985. Crown vetch, harvested 300 m from the nearest road, was fed as the control. The crops were fed as 50% dry weight of the diet for 58 d. The concentrations of lead in the control, 1979 crop, and 1985 crop were, respectively, 0.74, 50.65, and 6.78 ppm dry weight. The average +/- SE) concentrations (ppm, dry weight) of lead found in the tissues of the control, 1979, and 1985 dietary-treatment animals were, respectively, kidney, 0.36 +/- 0.05, 5.78 +/- 0.72, and 0.79 +/- 0.09; liver, 0.09 +/- 0.01, 4.71 +/- 0.17, and 0.46 +/- 0.06; muscle, 0.07 +/- 0.01, 0.14 +/- 0.02, and 0.07 +/- 0.00; blood, 0.09 +/- 0.02, 2.17 +/- 0.13, and 0.31 +/- 0.05; and bone, 1.27 +/- 0.25, 47.52 +/- 7.05, and 3.71 +/- 0.65. No significant differences (p greater than 0.05) between dietary treatments were found in the general hematological analyses of the woodchucks. The ecological significance of these findings is discussed.

  2. Isolation and antibiotic resistance detection of Enterococcus gallinarums from Marmota himalayana%喜马拉雅旱獭源鹑鸡肠球菌的分离及其耐药性检测

    Institute of Scientific and Technical Information of China (English)

    2016-01-01

    目的 了解青藏高原喜马拉雅旱獭携带院内感染病原菌鹑鸡肠球菌情况,并检测其对临床常用抗菌药物的耐药性.方法 选择性培养基、革兰染色、生化反应和16S rRNA基因序列分析方法对细菌进行分离和鉴定;K-B纸片法检测菌株对15种抗菌药物的耐药情况,并应用PCR方法检测毒力基因和耐药基因.结果 79份喜马拉雅旱獭肠道样本中共分离到3株鹑鸡肠球菌,其中1株对利福平中介,3株均对奎奴普丁中介,对其他被检抗菌药物均敏感;未检测到常见肠球菌毒力基因(asa1、esp、hyl、gelE和cylA)和相关耐药基因.结论 首次在青藏高原旱獭粪便中分离到鹑鸡肠球菌,常见的毒力基因检测阴性,对常见抗菌药物敏感.

  3. The research of bubonic plague and the preventable tactics in Marmota Himarlayana in Qingzang area of China%青藏地区喜马拉雅旱獭的鼠疫及防治策略

    Institute of Scientific and Technical Information of China (English)

    井燕; 徐来祥; 王玉山

    2007-01-01

    从喜马拉雅旱獭的生物学特征,鼠疫的危害,喜马拉雅旱獭鼠疫的发生与分布特点以及鼠疫检测的方法等方面,论述了多年来我国学者对喜马拉雅旱獭鼠疫研究的进展,进而提出了鼠疫的防治策略.

  4. What's Happening in February?

    Science.gov (United States)

    Weissman, Ron; And Others

    Brief information is given on 12 February events celebrated by Puerto Ricans: Groundhog Day; Candlemas; St. Valentine's Day; Mardi Gras; Ash Wednesday; Black History; and the birthdays of Thomas Alva Edison, Abraham Lincoln, Susan B. Anthony, Julia de Burgos, Luis Munoz Marin, and George Washington. Designed as a teacher resource, the booklet…

  5. 中国旱獭去唾液酸糖蛋白受体糖基结合域的原核表达与多克隆抗体的制备%Cloning, prokaryotic expression and polyclonal antibody preparation of the asialoglycoprotein receptor of marmota himalayan

    Institute of Scientific and Technical Information of China (English)

    杨燕; 黄凰; 刘慎沛; 张振华; 王宝菊; 田拥军; 杨东亮

    2007-01-01

    目的:构建中国旱獭去唾液酸糖蛋白受体(ASGPR)H1和H2亚基糖基识别域(CRD)的原核表达质粒,体外表达纯化后制备多克隆抗体.方法:RT-PCR扩增出中国旱獭肝组织中ASGPR CRDH1和CRDH2 cDNA,将其克隆至原核表达载体pRSET-B中,在大肠杆菌BL21(DE3)pLysS内诱导表达.用纯化的重组蛋白免疫BALB/c小鼠制备多克隆抗体,并采用酶联免疫吸附试验、Western blot及免疫组织化学检测抗体的灵敏度和特异性.结果:成功构建了中国旱獭去唾液酸糖蛋白受体H1和H2亚基糖基识别域原核表达质粒pRSET-B.CRDH1和pRSET-B.CRDH2,目的蛋白可以高效表达,用其免疫BALB/c小鼠获得了高效价的特异性多克隆抗体.结论:首次成功表达了中国旱獭去唾液酸糖蛋白受体H1和H2亚基糖基识别域多肽,且纯度高,免疫原性强,用其免疫小鼠获得的多克隆抗体特异性好、效价高,为在HBV感染模型-中国旱獭体内进行肝脏疾病的靶向治疗奠定了实验基础.

  6. Dicty_cDB: Contig-U15566-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 1 ( AL935140 ) Zebrafish DNA sequence from clone DKEYP-122E7 in ... 48 1.2 1 ( EF555519 ) Marmota himalay...ana clone W41 microsatellite seque... 48 1.2 1 ( AM446059 ) Vitis vinifera contig V

  7. Permanent genetic resources added to Molecular Ecology Resources Database 1 June 2012-31 July 2012.

    Science.gov (United States)

    Barat, Ashoktaru; Bravo, S P; Chandra, Suresh; Corrêa, A S; Giombini, M I; Guedes, R N C; Huailei, Ma; Lal, Kuldeep K; Liang, Lu; Matura, Rakesh; Mohindra, Vindhya; Oliveira, L O; Patangia, Ruchi; Qiyong, Liu; Sah, Rama Shankar; Singh, Akanksha; Singh, Birender Kumar; Singh, Rajeev K; Tosto, D S; Tripathi, Ratnesh K; Vinson, C C

    2012-11-01

    This article documents the addition of 96 microsatellite marker loci to the Molecular Ecology Resources Database. Loci were developed for the following species: Clarias batrachus, Marmota himalayana, Schizothorax richardsonii, Sitophilus zeamais and Syagrus romanzoffiana. These loci were cross-tested on the following species: Clarias dussumeri, Clarias gariepinus, Heteropneustus fossilis, Sitophilus granarius and Sitophilus oryzae.

  8. Animal models for HCV and HBV studies

    Directory of Open Access Journals (Sweden)

    Isabelle Chemin

    2007-02-01

    the infectivity of infectious clones of HCV without chimpanzees. Chimpanzees became infected when RNA transcripts from molecular clones were inoculated directly into the liver. The infection generated by such transfection did not differ significantly from that observed in animals infected intravenously with wild-type HCV. It furthermore permits true homologous challenge in studies of protective immunity and in testing the efficacy of vaccine candidates.

    Finally, this in vivo transfection system has made it possible to test for the first time the importance of genetic elements for HCV infectivity.

    Although chimpanzees are the only animals fully permissive for HBV infection, their use for research purpose is severely limited by the high costs and strong ethical constrains. The only alternative source of HBV-permissive hepatocytes is the Asian tree shrew Tupaia belangeri. Though experimental infection of these squirrel-like mammals, phylogenetically related to primates, results only in a mild, transient replication, primary hepatocytes isolated from T. belangeri turned out to be a reliable tool for in vitro HBV infection experiments.

    Along with invaluable infection studies in chimpanzees, avian and mammalian HBV-related viruses continue to offer ample opportunities for studies in naturally occurring hosts. In general, most of our progresses in hepatitis B virus research are based on infection studies with two HBV-related animal viruses: the woodchuck HBV (WHV, which infects the Eastern American woodchuck (Marmota monax, and the duck HBV (DHBV, which infects Peking ducks. Both animal models have been essential for understanding various steps of viral life-cycle and factors involved in establishment of virus

  9. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: "Flamenkofantaasiad" 2. mail Jõhvi kontserdimajas, "Frank Sinatra gala" 6. mail Vanemuise kontserdisaalis, 7. mail Pärnu kontserdimajas ja 9. mail Tallinna Linnahallis, Brides in Bloom 2. mail Tallinnas Rock Cafes, Demis Roussos 6. mail Saku Suurhallis, Vaiko Epilk ja Eliit heliplaadi "3: Kosmoseodüsseia" esitluskontsert 8. mail Rock Cafés, Chalice'i ja Jürmo Eespere trio kontserdist 6. mail Estonia Talveaias, Ultima Thule, Evergreen 86, Groundhog Day rokk-kontserdil 2. mail Tartus Vabaduse puiesteel

  10. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: "Flamenkofantaasiad" 2. mail Jõhvi kontserdimajas, "Frank Sinatra gala" 6. mail Vanemuise kontserdisaalis, 7. mail Pärnu kontserdimajas ja 9. mail Tallinna Linnahallis, Brides in Bloom 2. mail Tallinnas Rock Cafes, Demis Roussos 6. mail Saku Suurhallis, Vaiko Epilk ja Eliit heliplaadi "3: Kosmoseodüsseia" esitluskontsert 8. mail Rock Cafés, Chalice'i ja Jürmo Eespere trio kontserdist 6. mail Estonia Talveaias, Ultima Thule, Evergreen 86, Groundhog Day rokk-kontserdil 2. mail Tartus Vabaduse puiesteel

  11. The paternity of Madalena: a case of authorship attribution

    Directory of Open Access Journals (Sweden)

    Deise Joelen Tarouco de Freitas

    2017-07-01

    Full Text Available This article belongs to the area of study of authorship attribution. We study the case of a short story published in a newspaper called A Marmota, in 1859, in Rio de Janeiro, Brazil. The signature of the text was M. de A., the same signature used by two brazilian writers that collaborated with A Marmota, at the same time. One of them was Machado de Assis, the most iconic and canonic Brazilian writer, and the other was an almost unknown writer called Manuel D. Moreira de Azevedo.  In this work, we use the program Hyperbase that can turn the corpus in a big database. We analyze here the structural data by differents algorithms and arrive to an authentication.

  12. A sanção da toleima: em "Marquesa, porque eu serei marquês"

    Directory of Open Access Journals (Sweden)

    Maria Angélica Seabra Rodrigues Martins

    1990-10-01

    Full Text Available Em 1861, Machado de Assis publicou em A Marmota uma série de artigos, posteriormente reunidos em Miscelânea (2, 1962, na forma de um . opúsculo. Sob o título de "Queda que as mulheres têm para os tolos", o Autor define aí sua filosofia acerca do relacionamento homem/mulher onde esta, segundo os ditames da sociedade do século XIX, era apenas um meio utilizado pelo homem, através do contrato matrimonial, para ascender social e politicamente.

  13. New Mycomya species from the Himalayas (Diptera, Mycetophilidae): 2. Subgenera Calomycomya, Cymomya, Neomycomya and Pavomya subg. n.

    Science.gov (United States)

    Väisänen, Rauno

    2013-01-01

    Myconya Rondani specimens from the Himalayas, mostly Nepal and Myanmar, are revised. Pavoniya subg. n. is described. Altogether nine species from the subgenera Calomycoinya, Cymnoniya, Neoinycoinya and Pavomya subg. n. are recorded from the Himalayas and Indian subcontinent. The paper includes a key to the subgenera of Myconiya and the Himalayan species of Mycomya of the four subgenera. The following eight new species are described: M. aonyx, M. cuon, M. kainbaitiensis, M. marmota, M. paguina, M. panthera, M. ratufa and M. wah. Mycomyafiubriata (Meigen) is recorded from Myanmar.

  14. A NEW SPECIES OF THE GENUS NEOTROMBICULA FROM QINGHAI,CHINA(ACARI:TROMBICULIDAE)%青海省新恙螨属一新种(蜱螨亚纲:恙螨科)

    Institute of Scientific and Technical Information of China (English)

    吴克梅; 李超

    2001-01-01

    This paper reports a new species of the genus Neotrombicula.All measurements are given in micrometers. Neotrombicula paramarmotae sp.nov. (Figs.1-4)   Idiosoma measuring (188-266)×(165-218) in unengored specimens. SIF=7Bs-N-3-2111-1000. fp=B.B.NNB/7Bs. Gnathobase lightly punctate. Scutum pentagonal in shape, with punctations on its surface, AL/AM, SB/PL, PL>AL> AM; sensillae flagelliform, with 6-8 branches on distal half; PW/SD=1.37-1.40. Eyes 2.2, anterior larger. Dorsal setae 52-54 , arranged 2-10-2-10-2-10-6-6-4-2. Sternal setae 2.2. 26 preanal setae, 16 post-anal setae. NDV=94-96. Coxal setae 1.1.1, Ⅰ=245-500, Ⅱ=209-215, Ⅲ=241-255, IP=709-723.   This new species is mostly similar to N. marmotae Wen, 1984 it can be separated from the latter in having dorsal idiosomal setae arranged beginning 10-2-10-2(12-15-10-10 in N.marmotae), palpal genu seta with 5 branches, ventral seta on the palpal tibia with 5 branches,standerd measurements on the scutum are short: AW 69, PW 81, SB 27, AP 27,(AW 71,PW 95, SB 33, AP 34, in N.marmotae) , NDV=94-96, (NDV=104 in N.marmotae).   Holotype,3 paratypes,larvae collected off Pitymys irene Thomas, 1911,  17 Jun. 1995 from Minhe County (36°36′N,102°56′E),Qinghai Province.The type specimens are deposited in the Research Institute of Endemic Disease Control of Qinghai Province.%记述新恙螨属Neotrombicula Hirst,1925 一新种,拟旱獭新恙螨Neotrombicula paramarmotae sp.nov.,模式标本采自民和县的松田鼠Pitymys irene Thomas,1911体上。标本存放在青海省地方病防治研究所。量度单位均为μm。

  15. Power Characterisation for Fine-Grain Reconfigurable Fabrics

    Directory of Open Access Journals (Sweden)

    Tobias Becker

    2010-01-01

    Full Text Available This paper proposes a benchmarking methodology for characterising the power consumption of the fine-grain fabric in reconfigurable architectures. This methodology is part of the GroundHog 2009 power benchmarking suite. It covers active and inactive power as well as advanced low-power modes. A method based on random number generators is adopted for comparing activity modes. We illustrate our approach using five field-programmable gate arrays (FPGAs that span a range of process technologies: Xilinx Virtex-II Pro, Spartan-3E, Spartan-3AN, Virtex-5, and Silicon Blue iCE65. We find that, despite improvements through process technology and low-power modes, current devices need further improvements to be sufficiently power efficient for mobile applications. The Silicon Blue device demonstrates that performance can be traded off to achieve lower leakage.

  16. Stars on Local Time: A Personal Almanac

    Science.gov (United States)

    Gottlieb-Roberts, M.

    2016-01-01

    First presented at INSAP VIII, the artwork A Personal Almanac is my interpretation of the familiar seasons-of-life allegory. The booklet's eight pairs of seasonal pages— spring equinox through the cross-quarter Groundhog Day—portray a life in the decades from the 1940s to the 2010s under the stars of rural Georgia, France, Miami, West Africa and the other places I have lived. A Personal Almanac is included in the art book A Durable Tale, the illustrated story of my thirty-year search in the Southeast United States and in West Africa for living memories of old star almanacs. In that odyssey I uncovered some very deep roots for an oral literature of the African desert, the nomadic bard's star story that I believe inspired creation of the first nine tablets of the standard version Babylonian Gilgamesh.

  17. Once upon an algorithm how stories explain computing

    CERN Document Server

    Erwig, Martin

    2017-01-01

    How Hansel and Gretel, Sherlock Holmes, the movie Groundhog Day, Harry Potter, and other familiar stories illustrate the concepts of computing. Picture a computer scientist, staring at a screen and clicking away frantically on a keyboard, hacking into a system, or perhaps developing an app. Now delete that picture. In Once Upon an Algorithm, Martin Erwig explains computation as something that takes place beyond electronic computers, and computer science as the study of systematic problem solving. Erwig points out that many daily activities involve problem solving. Getting up in the morning, for example: You get up, take a shower, get dressed, eat breakfast. This simple daily routine solves a recurring problem through a series of well-defined steps. In computer science, such a routine is called an algorithm. Erwig illustrates a series of concepts in computing with examples from daily life and familiar stories. Hansel and Gretel, for example, execute an algorithm to get home from the forest. The movie Groundho...

  18. Nietzsche, and the life as a work of art

    Directory of Open Access Journals (Sweden)

    Marcia Beatriz Bello

    2010-11-01

    Full Text Available Through the proposals of the philosopher Friedrich Nietzsche regarding life-affirmation in spite of all the inherent pain and suffering, we will see how it is possible, according to the author, to live life as if it was an artistic work. To do this, we briefly use terms as Eternal Recurrence, Amor Fati, and Dionysian Wisdom. Towards the end, we briefly analyse the movie Groundhog Day. This article was prepared as the basis for the workshop/seminar presented during the Latin American and Caribbean Summit on Arts Education (Cumbre Latinoamericana y del Caribe de Arte y Educación, that took place in Bogota in November 2009.

  19. Eruption styles of Quaternary basalt in the southern Sierra Nevada Kern Plateau recorded in outcrop and mineral-scale stratigraphies

    Science.gov (United States)

    Browne, B. L.; Becerra, R. A.

    2015-12-01

    The Kern River Plateau in the southern Sierra Nevada contains Quaternary basalt (~0.1 km3) and rhyolite (~2 km3) that ascended through ~30 km of Mesozoic granitic crust. Basaltic vents include from oldest to youngest: Little Whitney Cone, Tunnel and South Fork Cones, and unglaciated Groundhog Cone. Little Whitney Cone is a 120-m-high pile of olivine-CPX-phyric scoria overlying two columnar jointed lava flows extending to the south and east. Tunnel Cone formed through a Hawaiian style eruption along a 400-m-long north-south trending fissure that excavated at least three 25-65-m-wide craters. Crater walls up to 12 meters high are composed of plagioclase-olivine-phyric spatter-fed flows that dip radially away from the crater center and crumble to form steep unconsolidated flanks. South Fork Cone is a 170-m-tall pile of plagioclase-olivine-phyric scoria that formed as a result of Strombolian to violent Strombolian eruptions. It overlies the South Fork Cone lava, the largest lava flow of the Kern Plateau (~0.05 km3), which flowed 7.5 km west into the Kern River Canyon. Scoria and ash fall deposits originating from South Fork Cone are found up to 2 km from the vent. Groundhog Cone is a 140-m-tall cinder and spatter cone breached on the north flank by a 0.03 km3 lava flow that partially buried the South Fork Cone lava and extends 5 km west to Kern River Canyon. Trends in mineral assemblage, texture, composition, and xenocryst abundance exist as a function of eruption style. Scoria and spatter deposits typically have (1) elevated olivine/plagioclase ratios, (2) oscillatory zoned (An63-An72) plagioclase phenocrysts surrounded by unzoned rims and (3) abundant xenocrysts, where up to 20% of plagioclase >200 micron diameter in some samples are granitoid xenocrysts with resorbed and/or reacted textures overprinted by abrupt compositional changes. In contrast, lava flow samples have (1) reduced olivine/plagioclase ratios and (2) plagioclase aggregates with oscillatory zoned

  20. 青海省群众猎捕旱獭的经验与方法

    Institute of Scientific and Technical Information of China (English)

    郑生武

    1981-01-01

    @@ 旱獭(Marmota hmalayana Hodgson)俗称哈拉,是青海高原草甸草原上广泛栖息的动物,数量很大,它是一种具有较高的经济价值的狩猎动物.旱獭皮是我国传统出口商品,肉、油可食.油还是工业上制造高级润滑油的原料.我省广大农牧民群众素有措捕习惯,群众猎捕旱獭的经验与方法是极其丰富的.自己因工作的关系,十几年来向群众学习了许多猎捕旱獭的经验与方法.结合个人体会,总结于下.

  1. [Origin of the plague microbe Yersinia pestis: structure of the process of speciation].

    Science.gov (United States)

    Suntsov, V V

    2012-01-01

    The origin and evolution of the plague microbe Yersinia pestis are considered in the context of propositions of modern Darwinism. It was shown that the plague pathogen diverged from the pseudotuberculous microbe Yersinia pseudotuberculosis O:1b in the mountain steppe landscapes of Central Asia in the Sartan: 22000-15000 years ago. Speciation occurred in the tarbagan (Marmota sibirica)--flea (Oropsylla silantiewi) parasitic system. The structure of the speciation process included six stages: isolation, genetic drift, enhancement of intrapopulational polymorphism, the beginning of pesticin synthesis (genetic conflict and emergence of hiatus), specialization (stabilization of characteristics), and adaptive irradiation (transformation of the monotypic species Y. pestis tarbagani into a polytypic species). The scenario opens up wide prospects for construction of the molecular phylogeny of the plague microbe Y. pestis and for investigation of the biochemical and molecular-genetic aspects of "Darwinian" evolution of pathogens from many other nature-focal infections.

  2. Association Between Himalayan Marmot Density and Climatic Factor

    Institute of Scientific and Technical Information of China (English)

    WEI Rong-jie; WANG Hu; HE Jian; JIN Yong; ZHENG Yi; DAI Rui-xia; YANG Yong-hai; XIONG Hao-ming; TIAN Fu-zhang; WANG Zu-yun

    2014-01-01

    Objective: This study aims to explore the association between the density of Himalayan marmot (Marmota himalayana) and climatic factors such as temperature, precipitation, humidity, vapour pressure, sunshine percentage, wind velocity, which are closely associated with global climate change, and to provide a reference for plague prevention and control. Methods: We conducted a regression analysis to find the possible climate factors associated with the density of Himalaya marmot, and analyzed the response characters of Himalayan marmot to climate change. Results:Daily precipitation days (>=0.1 mm) and sunshine percentage were significantly associated with the density of Himalayan marmot ( p<0.01). Conclusion:Climate change was associated with the risk of plague. This phenomenon is valuable for Himalayan marmot and plague prevention. More studies are needed to understand the impact of climate change on Himalayan marmot and plague.

  3. [Macro- and microevolution as related to the problem of origin and global expansion of the plague pathogen Yersinia pestis].

    Science.gov (United States)

    Suntsov, V V; Suntsova, N I

    2008-01-01

    The ratio of macro- and microevolutionary processes is considered with reference to the ecological scenario of the origin of the plague pathogen and its subsequent natural and anthropogenic global expansion. The macroevolutionary transformation of the ancestral pseudotuberculosis microbe clone into the initial plague microbe Yersinia pestis tarbagani occurred in Central Asia at the end of the Late Pleistocene by a "vertical" Darwinian way in an inadaptive heterothermal continual intermediate environment--the Mongolian marmot Marmota sibirica-flea Oropsylla silantiewi system--via a sequence of unstable and currently extinct intermediate forms. Its natural geographic expansion on the "oil spot" principle in the postglacial time led to the microevolutionary formation of 20-30 hostal subspecies circulating in populations of the background species of burrowing rodents and pikas in arid areas of Eurasia. The intercontinental spread of the "marmot" and "rat" pathogen subspecies in the past few centuries has been exclusively anthropogenic, with the involvement of synanthropic (ship) rats.

  4. The interactive potential of post-modern film narrative - Frequency, Order and Simultaneity

    Directory of Open Access Journals (Sweden)

    Carlos Sena Caires

    2009-05-01

    Full Text Available A considerable number of contemporary films are now using narrative models that allow several adaptations on digital and interactive operating systems. This trend is seen in films such as Memento by Christopher Nolan (2000, Irréversible by Gaspar Noé (2002 and Smoking / No Smoking by Alain Resnais (1993, concerning the chronological organization of their narrative parts – here it is a question of order. Or in films such as Elephant by Gus Van Sant (2003, Groundhog Day by Harold Ramis, 1993 and Rashômon by Akira Kurosawa (1950, for the diegetic repetition – a question of frequency. Or even, in films such as Magnolia by Paul Thomas Anderson (1999 and Short Cuts by Robert Altman, 1993 which use the idea of expansion or compression of the narrative – a question of simultaneity. To change the accessibility of the cinematographic experience and to constantly re-evaluate the way in which the narrative tool is used, is from now on considered the interactive potential of the contemporary film narrative.

  5. [Analysis on the results of etiology and serology of plague in Qinghai province from 2001 to 2010].

    Science.gov (United States)

    Yang, Yonghai; Wang, Mei; Zhao, Xiaolong; Zhao, Zhongzhi; Zhang, Aiping; Wei, Rongjie; Wei, Baiqing; Wang, Zuyun

    2014-02-01

    To analyze the results of etiology and serology of plague among human and infected animals in Qinghai province from 2001 to 2010. Thirty-seven cases of human infected with plague, 53 541 different animal samples, 5 685 sets of vector insects flea and 49 039 different animal serum samples were obtained between 2001 and 2010. A total of 7 811 samples of serum from healthy farmers and herdsmen in 14 counties in Qinghai from 2005 to 2007 were collected. Yersinia pestis (Y. pestis) were detected in visceral and secretions from human, infected animals and vector insects, respectively. Plague antigen was detected by reverse indirect hemagglutination assay (RIHA) in those samples. Indirect hemagglutination assay (IHA) was used to test plague FI antibody in serum of human and infected animals. 37 human plague cases were confirmed, 21 strains of plague Y. pestis were isolated from human cases and 14 positive were detected out. 133 of 7 811 samples of human serum were IHA positive, with the positive rate at 1.7%. A total of 146 strains of plague were isolated from infected animals and vector insects, 99 out of which were from infected animals, with a ratio of Marmota himalayan at 72.7% (72/99) and the other 47 were from vector insects, with a ratio of callopsylla solaris at 68.1% (32/47). The number of IHA and PIHA positive were 300 and 10, respectively. A total of 3 animals and 3 insects species were identified as new epidemic hosts for plague. The natural plague focus of Microtus fuscus was discovered and confirmed and coexisted with natural focus of Marmota himalayan in Chengduo county, Yushu prefecture. The epidemic situation of plague is distributed mainly in Haixi, Yushu and Hainan prefectures. From 2001 to 2010, animal infected with plague was detected in successive years and human plague was very common in Qinghai. New infected animals and vector insects species and new epidemic areas were confirmed, hence the trend of plague prevalence for humans and animals is very

  6. 四川省鼠疫防治30年回顾%Review of Plague Control and Prevention in Sichuan Province, 1981 -2010

    Institute of Scientific and Technical Information of China (English)

    汪立茂; 吴朝学; 吴建林; 祝小平; 陈开华; 谢飞; 李光清; 罗志丹巴; 段勇军; 李帆; 祁腾

    2012-01-01

    Objective To provide strategy for plague prevention and control based on the analysis of plague prevention and control in Sichuan province during 1981 -2010. Methods The data of the plague surveillance in Sichuan province during 1981 - 2010 were collected,, arranged and analyzed. Experimental method was accordance with the " diagnostic criteria for plague". Results Totally 42 429 bacteriological materials were tested, 183 strains of yersinia pestis were isolated In indirect tests of blood, 29 980 suspected plague serum smples were tested, in which 251 were positive. Radioimmunoassay precipitation test showed that 79 in 7 611 samples were positive. Reverse suspected plague detection showed that 31 in 833 were positive. Seven species of infected animals and 3 infected medium were found. The Microtus fuscus and the Marmota himalayana plague bacteria were found. And plague occurred in 5 towns and 2 counties. Conclusion The existence of natural foci of plague in Sichuan was confirmed, and Microtus fuscus plague foci and natural foci of the himalayana marmota were found.%目的 分析四川省1981-2010年鼠疫防治的研究结果,为四川鼠疫防控工作提供对策与依据.方法 统计、整理、分析四川省1981-2010年鼠疫相关工作资料,实验方法按照“鼠疫诊断标准”进行.结果 通过调查,细菌学检测材料42 429份、分离鼠疫菌183株,鼠疫间接血疑试验血清29 980份、阳性251份,鼠疫放射免疫沉淀试验标本7 611份、阳性79份,鼠疫反向血疑试验检测标本833份、阳性31份,发现染疫动物7种,染疫媒介3种,发现青海田鼠型鼠疫菌和喜马拉雅旱獭型鼠疫菌,鼠疫发生在2县5个乡镇.结论 证实了四川鼠疫自然疫源地的存在,发现了青海田鼠疫源地和喜马拉雅旱獭鼠疫自然疫源地.

  7. Delivery mechanisms of 3D geological models - a perspective from the British Geological Survey

    Science.gov (United States)

    Terrington, Ricky; Myers, Antony; Wood, Ben; Arora, Baneet

    2013-04-01

    The past decade has seen the British Geological Survey (BGS) construct over one hundred 3D geological models using software such as GOCAD®, GSI3D, EarthVision and Petrel across the United Kingdom and overseas. These models have been produced for different purposes and at different scales and resolutions in the shallow and deep subsurface. Alongside the construction of these models, the BGS and its collaborators have developed several options for disseminating these 3D geological models to external partners and the public. Initially, the standard formats for disseminating these 3D geological models by the BGS comprised of 2D images of cross-sections, GIS raster data and specialised visualisation software such as the LithoFrame Viewer. The LithoFrame Viewer is a thick-client software that allows the user to explore the 3D geometries of the geological units using a 3D interface, and generate synthetic cross-sections and boreholes on the fly. Despite the increased functionality of the LithoFrame Viewer over the other formats, the most popular data formats distributed remained 2D images of cross-sections, CAD based formats (e.g. DWG and DXF) and GIS raster data of surfaces and thicknesses, as these were the types of data that the external partners were most used too. Since 2009 software for delivering 3D geological models has advanced and types of data available have increased. Feature Manipulation Engine (FME) has been used to increase the number of outputs from 3D geological models. These include: • 3D PDFs (Adobe Acrobat) • KMZ/KML (GoogleEarth) • 3D shapefiles (ESRI) Alongside these later outputs, the BGS has developed other software such as GroundhogTM and Geovisionary (in collaboration with Virtalis). Groundhog is fully a web based application that allows the user to generate synthetic cross-sections, boreholes and horizontal slices from 3D geological models on the fly. Geovisionary provides some of the most advanced visualisation of 3D geological models in

  8. Community building - an essential ingredient of the IT infrastructure

    Science.gov (United States)

    Kessler, Holger; Mathers, Steve; Gunnink, Jan

    2015-04-01

    Many Geological Survey Organisations (GSO) are now building systematic 3D geological models as part of their core programme. Until recently the key players from the GSOs only met occasionally at international conferences and workshops, often in the US during the annual meetings of the Geological Society of America (http://crystal.isgs.uiuc.edu/research/3DWorkshop/index.shtml). After summarising the activities of various leading GSOs in a single document by Berg et al (2010) Synopsis of current three-dimensional geological mapping and modelling in Geological Survey organizations http://nora.nerc.ac.uk/17095/) it was decided in 2013 that more regular meetings should be held in Europe to foster linkages, encourage collaboration, and most importantly share successes and resources and avoid duplication of effort and repetition of mistakes. The initial European 3D Geological Modelling Meeting was hosted by TNO in 2013. The second was held in October 2014 at BGS Edinburgh with 85 staff from 20 GSO's and academic institutions represented. This paper will present the objectives of this community, some outcomes and a plan for the future. As much as good communication between model builders is desirable, it is of course even more essential to have a strong dialogue with the end users, to this end the British Geological Survey recently hosted a well-attended seminar at the Geological Society in London presenting their recently completed geological model of London and the Thames Valley (http://www.bgs.ac.uk/research/ukGeology/nationalGeologicalModel/londonAndThamesValley.html) and the latest web-based delivery mechanism which was designed after extensive consultation with the user community (https://shop.bgs.ac.uk/Groundhog/). Meanwhile in the Netherlands the DINOloket web portal (https://www.dinoloket.nl/) is continuing to adapt to end users needs - the paper will give an update on these and other initiatives.

  9. Exploring the Bone Proteome to Help Explain Altered Bone Remodeling and Preservation of Bone Architecture and Strength in Hibernating Marmots.

    Science.gov (United States)

    Doherty, Alison H; Roteliuk, Danielle M; Gookin, Sara E; McGrew, Ashley K; Broccardo, Carolyn J; Condon, Keith W; Prenni, Jessica E; Wojda, Samantha J; Florant, Gregory L; Donahue, Seth W

    2016-01-01

    Periods of physical inactivity increase bone resorption and cause bone loss and increased fracture risk. However, hibernating bears, marmots, and woodchucks maintain bone structure and strength, despite being physically inactive for prolonged periods annually. We tested the hypothesis that bone turnover rates would decrease and bone structural and mechanical properties would be preserved in hibernating marmots (Marmota flaviventris). Femurs and tibias were collected from marmots during hibernation and in the summer following hibernation. Bone remodeling was significantly altered in cortical and trabecular bone during hibernation with suppressed formation and no change in resorption, unlike the increased bone resorption that occurs during disuse in humans and other animals. Trabecular bone architecture and cortical bone geometrical and mechanical properties were not different between hibernating and active marmots, but bone marrow adiposity was significantly greater in hibernators. Of the 506 proteins identified in marmot bone, 40 were significantly different in abundance between active and hibernating marmots. Monoaglycerol lipase, which plays an important role in fatty acid metabolism and the endocannabinoid system, was 98-fold higher in hibernating marmots compared with summer marmots and may play a role in regulating the changes in bone and fat metabolism that occur during hibernation.

  10. The Bonneville Estates Rockshelter rodent fauna and changes in Late Pleistocene-Middle Holocene climates and biogeography in the Northern Bonneville Basin, USA

    Science.gov (United States)

    Schmitt, Dave N.; Lupo, Karen D.

    2012-07-01

    Excavations at Bonneville Estates Rockshelter, Nevada recovered rodent remains from stratified deposits spanning the past ca. 12,500 14C yr BP (14,800 cal yr BP). Specimens from horizons dating to the late Pleistocene and early Holocene include species adapted to montane and moist and cool habitats, including yellow-bellied marmot (Marmota flaviventris) and bushy-tailed woodrat (Neotoma cinerea). Shortly after 9000 14C BP (10,200 cal yr BP) these mammals became locally extinct, or nearly so, taxonomic diversity declined, and the region became dominated by desert woodrats (Neotoma lepida) and other species well-adapted to xeric, low-elevation settings. The timing and nature of changes in the Bonneville Estates rodent fauna are similar to records reported from nearby Homestead and Camels Back caves and provide corroborative data on terminal Pleistocene-early Holocene environments and mammalian responses to middle Holocene desertification. Moreover, the presence of northern pocket gopher (Thomomys talpoides) at Bonneville Estates adds to a sparse regional record for that species and, similar to Homestead Cave, it appears that the ca. 9500 14C yr BP (10,800 cal yr BP) replacement of the northern pocket gopher by Botta's pocket gopher in the Great Salt Lake Desert vicinity was also in response to climate change.

  11. Small-mammal data on early and middle Holocene climates and biotic communities in the Bonneville Basin, USA

    Science.gov (United States)

    Schmitt, D.N.; Madsen, D.B.; Lupo, K.D.

    2002-01-01

    Archaeological investigations in Camels Back Cave, western Utah, recovered a series of small-mammal bone assemblages from stratified deposits dating between ca. 12,000 and 500 14C yr B.P. The cave's early Holocene fauna includes a number of species adapted to montane or mesic habitats containing grasses and/or sagebrush (e.g., Lepus townsendii, Marmota flaviventris, Reithrodontomys megalotis, and Brachylagus idahoensis) which suggest that the region was relatively cool and moist until after 8800 14C yr B.P. Between ca. 8600 and 8100 14C yr B.P. these mammals became locally extinct, taxonomic diversity declined, and there was an increase in species well-adapted to xeric, low-elevation habitats, including ground squirrels, Lepus californicus and Neotoma lepida. The early small-mammal record from Camels Back Cave is similar to the 11,300-6000 14C yr B.P. mammalian sequence from Homestead Cave, northwestern Utah, and provides corroborative data on Bonneville Basin paleoenvironments and mammalian responses to middle Holocene desertification. ?? 2002 University of Washington.

  12. Prey preferences of the snow leopard (Panthera uncia: regional diet specificity holds global significance for conservation.

    Directory of Open Access Journals (Sweden)

    Salvador Lyngdoh

    Full Text Available The endangered snow leopard is a large felid that is distributed over 1.83 million km(2 globally. Throughout its range it relies on a limited number of prey species in some of the most inhospitable landscapes on the planet where high rates of human persecution exist for both predator and prey. We reviewed 14 published and 11 unpublished studies pertaining to snow leopard diet throughout its range. We calculated prey consumption in terms of frequency of occurrence and biomass consumed based on 1696 analysed scats from throughout the snow leopard's range. Prey biomass consumed was calculated based on the Ackerman's linear correction factor. We identified four distinct physiographic and snow leopard prey type zones, using cluster analysis that had unique prey assemblages and had key prey characteristics which supported snow leopard occurrence there. Levin's index showed the snow leopard had a specialized dietary niche breadth. The main prey of the snow leopard were Siberian ibex (Capra sibrica, blue sheep (Pseudois nayaur, Himalayan tahr (Hemitragus jemlahicus, argali (Ovis ammon and marmots (Marmota spp. The significantly preferred prey species of snow leopard weighed 55±5 kg, while the preferred prey weight range of snow leopard was 36-76 kg with a significant preference for Siberian ibex and blue sheep. Our meta-analysis identified critical dietary resources for snow leopards throughout their distribution and illustrates the importance of understanding regional variation in species ecology; particularly prey species that have global implications for conservation.

  13. Stable isotopes reflect the ecological stability of two high-elevation mammals from the late Quaternary of Colorado

    Science.gov (United States)

    McLean, Bryan S.; Emslie, Steven D.

    2012-05-01

    The vertebrate fossil record of Cement Creek Cave, Colorado, spans from > 45,000 yr ago to the present and represents the richest stratified series of high-elevation (> 2900 m) mammal remains known from the late Quaternary of North America. Stable carbon and oxygen isotope analyses of tooth enamel were used to assess potential ecological responses of two species found commonly throughout the cave, Yellow-bellied marmots (Marmota flaviventris) and Bushy-tailed woodrats (Neotoma cinerea), to late Quaternary climate and environmental changes of the Southern Rocky Mountains. Results indicate that despite such perturbations, the dietary ecologies of both species were maintained across this period. Neither taxon shifted to consuming C4 taxa or different C3 functional groups; similarly, no significant shifts in surface water use were detected. Variations in enamel δ13C were observed, however, that represent the physiological responses of high-elevation plants to changing levels of late Quaternary atmospheric CO2. While our findings extend both the geographic and elevational record of this plant CO2 response, they simultaneously highlight the ecological stability of high-elevation M. flaviventris and N. cinerea during climate changes of late Quaternary magnitude.

  14. The Effect of Anthelmintic Treatment on Coccidia Oocyst Shedding in a Wild Mammal Host with Intermittent Cestode Infection

    Directory of Open Access Journals (Sweden)

    Radovan Václav

    2014-01-01

    Full Text Available While hosts are routinely exploited by a community of parasite species, the principles governing host responses towards parasites are unclear. Identifying the health outcomes of coinfections involving helminth macroparasites and microparasites is one area of importance for public and domestic animal health. For instance, it is controversial how deworming programmes affect incidence and severity of such important microparasite diseases as malaria. One problem is that most study systems involve domestic and laboratory animals with conditions hardly comparable to those of free-living animals. Here, we study the effect of anthelmintic treatment on coccidia infection intensity in wild Alpine marmots, M. marmota. Our results lend support to the hypothesis that helminth infection has a positive effect on concurrent microparasite infection. However, our work also points to the fact that within-host interactions between helminths and microparasites are context-dependent and can turn to negative ones once helminth burdens increase. Our study suggests that coccidia benefit from intermittent helminth infection in marmots due to the protective effects of helminth infection only during the early phase of the host’s active season. Also, the marmot’s response towards coccidia infection appears optimal only under no helminth infection when the host immune response towards coccidia would not be compromised, thereby pointing to the importance of regular intestinal helminth elimination by marmots just before hibernation.

  15. Small mammals of the Mongolian mountain steppe region near Erdensant: insights from live-trapping and bird pellet remains.

    Directory of Open Access Journals (Sweden)

    Joanne L. Isaac

    2005-12-01

    Full Text Available Relatively little is known of the distribution, abundance and ecology of small mammals in Mongolia and as a result there is scant knowledge of the effects of environmental and anthropogenic factors on small mammal populations. The aim of this study was to assess the occurrence of small mammals in mountain steppe habitat from live-trapping and analysis of mammal remains from raptor pellets and below nests. During live-trapping, root voles ( Microtus oeconemus were the most commonly caught species accounting for 47.5 % of captures, striped hamsters ( Cricetulus barabensis and pika ( Ochotona hyperborea accounted for 30 % and 22.5 % of captures respectively. Temperature influenced trapping success, with small mammals appearing to avoid being active at temperatures over 20 ̊C. The three species caught on the trapping grid appeared to avoid competition for resources through both temporal and spatial differences in the use of available habitat. Mammals identified from raptor pellets and other remains included the grey hamster ( Cricatulus migratorius , Siberian marmot ( Marmota sibirica , red fox ( Vulpes vulpes , long-tailed souslik ( Citellus undulatus and the Daurian mole ( Myospalax aspalax. Results are discussed in terms of their relevance to the conservation of mammals in Mongolia and their co-existence with livestock and humans.

  16. Mapping risk of plague in Qinghai-Tibetan Plateau, China.

    Science.gov (United States)

    Qian, Quan; Zhao, Jian; Fang, Liqun; Zhou, Hang; Zhang, Wenyi; Wei, Lan; Yang, Hong; Yin, Wenwu; Cao, Wuchun; Li, Qun

    2014-07-10

    Qinghai-Tibetan Plateau of China is known to be the plague endemic region where marmot (Marmota himalayana) is the primary host. Human plague cases are relatively low incidence but high mortality, which presents unique surveillance and public health challenges, because early detection through surveillance may not always be feasible and infrequent clinical cases may be misdiagnosed. Based on plague surveillance data and environmental variables, Maxent was applied to model the presence probability of plague host. 75% occurrence points were randomly selected for training model, and the rest 25% points were used for model test and validation. Maxent model performance was measured as test gain and test AUC. The optimal probability cut-off value was chosen by maximizing training sensitivity and specificity simultaneously. We used field surveillance data in an ecological niche modeling (ENM) framework to depict spatial distribution of natural foci of plague in Qinghai-Tibetan Plateau. Most human-inhabited areas at risk of exposure to enzootic plague are distributed in the east and south of the Plateau. Elevation, temperature of land surface and normalized difference vegetation index play a large part in determining the distribution of the enzootic plague. This study provided a more detailed view of spatial pattern of enzootic plague and human-inhabited areas at risk of plague. The maps could help public health authorities decide where to perform plague surveillance and take preventive measures in Qinghai-Tibetan Plateau.

  17. Spatial prediction and analysis of Himalayan marmot plague natural epidemic foci in China based on HJ-1 satellite data

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Plague,caused by the gram-negative bacterium Yersinia pestis,is a serious and rapidly progressing illness in humans that can be fatal if not treated effectively.The Qinghai-Tibet Plateau is the largest area of natural Himalayan marmot(Marmota himalayana) plague foci in China and covers more than 630000 km2.Akesai County in Gansu Province is a part of this natural focus of plague and was chosen as a study area.Our study used an ecological niche modeling(ENM) approach to predict the potential distribution of the Himalayan marmot.Environment and Disaster Monitor Satellite(HJ-1) data was used to investigate environment factors that affect plague host animal activity.Host animal point data from active surveillance was combined with environmental variables from the HJ-1 satellite and other databases,and the models of the potential distribution of Himalayan marmot were produced with the Genetic Algorithm for Rule-Set Production(GARP).The probability of marmot presence was divided into 0-5%,5%-20%,20%-40%,40%-80%,and 80%-100% subgroups.Areas with 80%-100% probability exhibited the greatest potential for the presence of Himalayan marmot.According to the predicted potential distribution of Himalayan marmot in the study area,active surveillance of plague hosts and plague control and prevention could be more efficient.

  18. Effects of tourists on behavior and demography of Olympic marmots.

    Science.gov (United States)

    Griffin, Suzanne C; Valois, Tanguy; Taper, Mark L; Scott Mills, L

    2007-08-01

    If changes in animal behavior resulting from direct human disturbance negatively affect the persistence of a given species or population, then these behavioral changes must necessarily lead to reduced demographic performance. We tested for the effects of human disturbance on Olympic marmots (Marmota olympus), a large ground-dwelling squirrel that has disappeared from several areas where recreation levels are high. We assessed the degree to which antipredator and foraging behavior and demographic rates (survival and reproduction) differed between sites with high recreation levels (high use) and those with little or no recreation (low use). Compared with the marmots at low-use sites, marmots at high-use sites displayed significantly reduced responses to human approach, which could be construed as successful accommodation of disturbance or as a decrease in predator awareness. The marmots at high-use sites also looked up more often while foraging, which suggests an increased wariness. Marmots at both types of sites had comparable reproductive and survival rates and were in similar body condition. Until now, the supposition that marmots can adjust their behavior to avoid negative demographic consequences when confronted with heavy tourism has been based on potentially ambiguous behavioral data. Our results support this hypothesis in the case of Olympic marmots and demonstrate the importance of considering demographic data when evaluating the impacts of recreation on animal populations.

  19. Methodology of determining soil structure in important groundwater areas: case studies in Kauvonkangas, Finnish Lapland

    Science.gov (United States)

    Kupila, Juho

    2016-04-01

    will also include the main flow directions of the groundwater. Structure models will be done with Groundhog -software. Kauvonkangas -project is funded by local water supply companies Meri-Lapin Vesi and Tervolan Vesi, Ministry of Agriculture and Forestry, and Geological Survey of Finland.

  20. Spatially explicit modelling of forest structure and function using airborne lidar and hyperspectral remote sensing data combined with micrometeorological measurements

    Science.gov (United States)

    Thomas, Valerie Anne

    This research models canopy-scale photosynthesis at the Groundhog River Flux Site through the integration of high-resolution airborne remote sensing data and micrometeorological measurements collected from a flux tower. Light detection and ranging (lidar) data are analysed to derive models of tree structure, including: canopy height, basal area, crown closure, and average aboveground biomass. Lidar and hyperspectral remote sensing data are used to model canopy chlorophyll (Chl) and carotenoid concentrations (known to be good indicators of photosynthesis). The integration of lidar and hyperspectral data is applied to derive spatially explicit models of the fraction of photosynthetically active radiation (fPAR) absorbed by the canopy as well as a species classification for the site. These products are integrated with flux tower meteorological measurements (i.e., air temperature and global solar radiation) collected on a continuous basis over 2004 to apply the C-Fix model of carbon exchange to the site. Results demonstrate that high resolution lidar and lidar-hyperspectral integration techniques perform well in the boreal mixedwood environment. Lidar models are well correlated with forest structure, despite the complexities introduced in the mixedwood case (e.g., r2=0.84, 0.89, 0.60, and 0.91, for mean dominant height, basal area, crown closure, and average aboveground biomass). Strong relationships are also shown for canopy scale chlorophyll/carotenoid concentration analysis using integrated lidar-hyperspectral techniques (e.g., r2=0.84, 0.84, and 0.82 for Chl(a), Chl(a+b), and Chl(b)). Examination of the spatially explicit models of fPAR reveal distinct spatial patterns which become increasingly apparent throughout the season due to the variation in species groupings (and canopy chlorophyll concentration) within the 1 km radius surrounding the flux tower. Comparison of results from the modified local-scale version of the C-Fix model to tower gross ecosystem

  1. Analysis of the carrot and stick policy of repeal of the sustainable growth rate formula: the good, the bad, and the ugly.

    Science.gov (United States)

    Manchikanti, Laxmaiah; Staats, Peter S; Boswell, Mark V; Hirsch, Joshua A

    2015-01-01

    The Balanced Budget Act which became law in 1997 was designed to help stem the increasing in costs of healthcare. The Sustainable Growth Rate (SGR) formula was incorporated into that law as a method of helping balance the budget through a complex formula tying reimbursement to the growth in the economy. Soon after its inception, the flawed nature of the formula, linking the balancing of the federal budget to physician professional fees was realized. Congress has provided multiple short-term fixes known as SGR patches over the years so as to avoid generally progressively larger negative corrections to professional reimbursement. The near annual SGR correction requirement has been compared to Groundhog Day in the legislative arena. Over the years, physician and other providers faced numerous looming, large cuts. Most recently, on April 1, 2015 physicians faced a 21.2% cut in provider payments. To the surprise of many, in April 2015 a bipartisan bicameral effort permanently repealed the Medicare SGR formula for controlling provider payment. The repeal of SGR means the temporary measures to override the growth rate formula will no longer dominate Medicare policy discussions and now the focus turns to continue payment reforms. The MACRA provides physicians and other health care professionals with stable fee update for 5 years and it follows with a new incentive program, termed the Merit-based Incentive Payment System (MIPS) replacing and consolidating pre-existing incentive payment programs: meaningful use of electronic health records (EHR), physician quality reporting system, and the value-based payment modified. Thus, payments to clinicians will be subjected to adjustments based on participation in MIPS or other approved alternative payment mechanisms. This legislation also creates numerous other regulations. The MACRA has been criticized for providing insufficient statutory updates, enacting a flawed quality and performance improvement program associated with MIPS

  2. Comprehensive analysis of gene expression patterns of hedgehog-related genes

    Directory of Open Access Journals (Sweden)

    Baillie David

    2006-10-01

    Full Text Available Abstract Background The Caenorhabditis elegans genome encodes ten proteins that share sequence similarity with the Hedgehog signaling molecule through their C-terminal autoprocessing Hint/Hog domain. These proteins contain novel N-terminal domains, and C. elegans encodes dozens of additional proteins containing only these N-terminal domains. These gene families are called warthog, groundhog, ground-like and quahog, collectively called hedgehog (hh-related genes. Previously, the expression pattern of seventeen genes was examined, which showed that they are primarily expressed in the ectoderm. Results With the completion of the C. elegans genome sequence in November 2002, we reexamined and identified 61 hh-related ORFs. Further, we identified 49 hh-related ORFs in C. briggsae. ORF analysis revealed that 30% of the genes still had errors in their predictions and we improved these predictions here. We performed a comprehensive expression analysis using GFP fusions of the putative intergenic regulatory sequence with one or two transgenic lines for most genes. The hh-related genes are expressed in one or a few of the following tissues: hypodermis, seam cells, excretory duct and pore cells, vulval epithelial cells, rectal epithelial cells, pharyngeal muscle or marginal cells, arcade cells, support cells of sensory organs, and neuronal cells. Using time-lapse recordings, we discovered that some hh-related genes are expressed in a cyclical fashion in phase with molting during larval development. We also generated several translational GFP fusions, but they did not show any subcellular localization. In addition, we also studied the expression patterns of two genes with similarity to Drosophila frizzled, T23D8.1 and F27E11.3A, and the ortholog of the Drosophila gene dally-like, gpn-1, which is a heparan sulfate proteoglycan. The two frizzled homologs are expressed in a few neurons in the head, and gpn-1 is expressed in the pharynx. Finally, we compare the

  3. Flood Risk Mapping Using LiDAR for Annapolis Royal, Nova Scotia, Canada

    Directory of Open Access Journals (Sweden)

    Tim L. Webster

    2010-09-01

    Full Text Available A significant portion of the Canadian Maritime coastline has been surveyed with airborne Light Detection and Ranging (LiDAR. The purpose of these surveys has been to map the risk of flooding from storm surges and projected long-term sea‑level rise from climate change and to include projects in all three Maritime Provinces: Prince Edward Island, New Brunswick, and Nova Scotia. LiDAR provides the required details in order to map the flood inundation from 1 to 2 m storm surge events, which cause coastal flooding in many locations in this region when they occur at high tide levels. The community of Annapolis Royal, Nova Scotia, adjacent to the Bay of Fundy, has been surveyed with LiDAR and a 1 m DEM (Digital Elevation Model was constructed for the flood inundation mapping. Validation of the LiDAR using survey grade GPS indicates a vertical accuracy better than 30 cm. A benchmark storm, known as the Groundhog Day storm (February 1–3, 1976, was used to assess the flood maps and to illustrate the effects of different sea-level rise projections based on climate change scenarios if it were to re-occur in 100 years time. Near shore bathymetry has been merged with the LiDAR and local wind observations used to model the impact of significant waves during this benchmark storm. Long-term (ca. greater than 30 years time series of water level observations from across the Bay of Fundy in Saint John, New Brunswick, have been used to estimate return periods of water levels under present and future sea-level rise conditions. Results indicate that under current sea-level rise conditions this storm has a 66 year return period. With a modest relative sea-level (RSL rise of 80 cm/century this decreases to 44 years and, with a possible upper limit rise of 220 cm/century, this decreases further to 22 years. Due to the uncertainty of climate change scenarios and sea-level rise, flood inundation maps have been constructed at 10 cm increments up to the 9 m contour

  4. Detection, Prevalence and Phylogenetic Relationships of Demodex spp and further Skin Prostigmata Mites (Acari, Arachnida) in Wild and Domestic Mammals

    Science.gov (United States)

    Sastre, Natalia; Francino, Olga; Curti, Joseph N.; Armenta, Tiffany C.; Fraser, Devaughn L.; Kelly, Rochelle M.; Hunt, Erin; Silbermayr, Katja; Zewe, Christine; Sánchez, Armand; Ferrer, Lluís

    2016-01-01

    This study was conceived to detect skin mites in social mammals through real-time qPCR, and to estimate taxonomic Demodex and further Prostigmata mite relationships in different host species by comparing sequences from two genes: mitochondrial 16S rRNA and nuclear 18S rRNA. We determined the mite prevalence in the hair follicles of marmots (13%) and bats (17%). The high prevalence found in marmots and bats by sampling only one site on the body may indicate that mites are common inhabitants of their skin. Since we found three different mites (Neuchelacheles sp, Myobia sp and Penthaleus sp) in three bat species (Miotis yumanensis, Miotis californicus and Corynorhinus townsendii) and two different mites (both inferred to be members of the Prostigmata order) in one marmot species (Marmota flaviventris), we tentatively concluded that these skin mites 1) cannot be assigned to the same genus based only on a common host, and 2) seem to evolve according to the specific habitat and/or specific hair and sebaceous gland of the mammalian host. Moreover, two M. yumanensis bats harbored identical Neuchelacheles mites, indicating the possibility of interspecific cross-infection within a colony. However, some skin mites species are less restricted by host species than previously thought. Specifically, Demodex canis seems to be more transmissible across species than other skin mites. D. canis have been found mostly in dogs but also in cats and captive bats. In addition, we report the first case of D. canis infestation in a domestic ferret (Mustela putorius). All these mammalian hosts are related to human activities, and D. canis evolution may be a consequence of this relationship. The monophyletic Demodex clade showing closely related dog and human Demodex sequences also supports this likely hypothesis. PMID:27802314

  5. Genetic basis of between-individual and within-individual variance of docility.

    Science.gov (United States)

    Martin, J G A; Pirotta, E; Petelle, M B; Blumstein, D T

    2017-04-01

    Between-individual variation in phenotypes within a population is the basis of evolution. However, evolutionary and behavioural ecologists have mainly focused on estimating between-individual variance in mean trait and neglected variation in within-individual variance, or predictability of a trait. In fact, an important assumption of mixed-effects models used to estimate between-individual variance in mean traits is that within-individual residual variance (predictability) is identical across individuals. Individual heterogeneity in the predictability of behaviours is a potentially important effect but rarely estimated and accounted for. We used 11 389 measures of docility behaviour from 1576 yellow-bellied marmots (Marmota flaviventris) to estimate between-individual variation in both mean docility and its predictability. We then implemented a double hierarchical animal model to decompose the variances of both mean trait and predictability into their environmental and genetic components. We found that individuals differed both in their docility and in their predictability of docility with a negative phenotypic covariance. We also found significant genetic variance for both mean docility and its predictability but no genetic covariance between the two. This analysis is one of the first to estimate the genetic basis of both mean trait and within-individual variance in a wild population. Our results indicate that equal within-individual variance should not be assumed. We demonstrate the evolutionary importance of the variation in the predictability of docility and illustrate potential bias in models ignoring variation in predictability. We conclude that the variability in the predictability of a trait should not be ignored, and present a coherent approach for its quantification. © 2017 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2017 European Society For Evolutionary Biology.

  6. Detection, Prevalence and Phylogenetic Relationships of Demodex spp and further Skin Prostigmata Mites (Acari, Arachnida) in Wild and Domestic Mammals.

    Science.gov (United States)

    Sastre, Natalia; Francino, Olga; Curti, Joseph N; Armenta, Tiffany C; Fraser, Devaughn L; Kelly, Rochelle M; Hunt, Erin; Silbermayr, Katja; Zewe, Christine; Sánchez, Armand; Ferrer, Lluís

    2016-01-01

    This study was conceived to detect skin mites in social mammals through real-time qPCR, and to estimate taxonomic Demodex and further Prostigmata mite relationships in different host species by comparing sequences from two genes: mitochondrial 16S rRNA and nuclear 18S rRNA. We determined the mite prevalence in the hair follicles of marmots (13%) and bats (17%). The high prevalence found in marmots and bats by sampling only one site on the body may indicate that mites are common inhabitants of their skin. Since we found three different mites (Neuchelacheles sp, Myobia sp and Penthaleus sp) in three bat species (Miotis yumanensis, Miotis californicus and Corynorhinus townsendii) and two different mites (both inferred to be members of the Prostigmata order) in one marmot species (Marmota flaviventris), we tentatively concluded that these skin mites 1) cannot be assigned to the same genus based only on a common host, and 2) seem to evolve according to the specific habitat and/or specific hair and sebaceous gland of the mammalian host. Moreover, two M. yumanensis bats harbored identical Neuchelacheles mites, indicating the possibility of interspecific cross-infection within a colony. However, some skin mites species are less restricted by host species than previously thought. Specifically, Demodex canis seems to be more transmissible across species than other skin mites. D. canis have been found mostly in dogs but also in cats and captive bats. In addition, we report the first case of D. canis infestation in a domestic ferret (Mustela putorius). All these mammalian hosts are related to human activities, and D. canis evolution may be a consequence of this relationship. The monophyletic Demodex clade showing closely related dog and human Demodex sequences also supports this likely hypothesis.

  7. Revision of the pollen beetle genus Meligethes (Coleoptera: Nitidulidae

    Directory of Open Access Journals (Sweden)

    Paolo Audisio

    2014-10-01

    Full Text Available A taxonomic revision of members of the genus Meligethes Stephens, 1830 is carried out. Taxonomic and distributional notes are provided on fiftythree Meligethes species, mostly known from the Eastern Palearctic and marginally from the Western Palearctic and the Oriental Regions. Among these, twentythree new species of Meligethes are diagnosed, figured and described: M. argentithorax sp. n. (Central China: Shaanxi, Shanxi, M. aurantirugosus sp. n. (Nepal, M. aureolineatus sp. n. (Central China: Sichuan, M. aurifer sp. n. (Central China: Shaanxi, Shanxi, M. brassicogethoides sp. n. (SW China: Yunnan, M. clinei sp. n. (SW China: Yunnan, M. elytralis sp. n. (Central China: Sichuan, M. ferruginoides sp. n. (Central China: Sichuan, M. cinereoargenteus sp. n. (Central China: Sichuan, M. henan sp. n. (Central China: Henan, M. luteoornatus sp. n. (SW China: Yunnan, M. marmota sp. n. (Nepal, M. nivalis sp. n. (SW and central China: Xizang and Chongqing, M. martes sp. n. (Central China: Shaanxi, Shanxi, Sichuan, M. nigroaeneus sp. n. (SW China: Yunnan, M. occultus sp. n. (SW China: Yunnan, M. pseudochinensis sp. n. (Central China: Hubei, M. pseudopectoralis sp. n. (SW China: Yunan, M. schuelkei sp. n. (Central China: Sichuan, Shaanxi, M. simulator sp. n. (Central-N China: Shanxi, M. stenotarsus sp. n. (SW China: Yunnan, Xizang, M. tryznai sp. n. (SW China: Yunnan, and M. volkovichi sp. n. (SW China: Yunnan. Revaluations at specific rank from synonymy are introduced for Meligethes lutra Solsky 1860, and for M. melleus Grouvelle, 1908. Three new synonymies are established: Meligethes brevipilus Kirejtshuk, 1980 = M. auripilis Reitter, 1889 (syn. n., Meligethes zakharenkoi Kirejtshuk, 2005 = M. shirakii Sadanari Hisamatsu, 1956 (syn. n., and Meligethes shirozui Sadanari Hisamatsu, 1965 = M. wagneri Rebmann, 1956 (syn. n.. Complete redescriptions are given for Meligethes binotatus Grouvelle, 1894, M. castanescens Grouvelle, 1903, M. ferrugineus Reitter, 1873

  8. Investigation on Yesinia Enterocolitica in Some Plateau Areas of Sichuan%四川部分高原地区小肠结肠炎耶尔森菌调查

    Institute of Scientific and Technical Information of China (English)

    祁腾; 李民杰; 罗科; 尕让尼玛; 罗隆泽; 汪立茂; 马丽; 陈开华; 曾明才; 吴朝学; 张小兵; 黎能金

    2011-01-01

    目的 为了解四川省高原地区喜马拉雅旱獭是否携带小肠结肠炎耶尔森菌及该菌是否和鼠疫耶尔森菌存在共生关系.方法 鼠疫常规监测中捕获的喜马拉雅旱獭,解剖时无菌操作取舌根和回盲肠内容物,置于准备好的10~15 ml改良PBS增菌培养管中,在4℃冰箱中增菌10~20 d后分离培养.结果 在德格县采样100份,分离小肠结肠炎耶尔森2株,若尔盖县采样148份,分离小肠结肠炎耶尔森菌1株.结论 四川省高原地区喜马拉雅早獭携带小肠结肠炎结肠炎耶尔森菌,该菌和鼠疫耶尔森菌可能存在共生关系.%Objective To understand whether the Himalayan marmots which lived in Sichuan Westem Plateau carrying Yersinia enterocolitica, and investigate whether the symbiotic relationship exists between Yersinia enterocolitica and Yersinia pestis. Methods The Himalayan marmots in this study were captured from routine monitoring of plague, tongue basis and the contents in cecum were taken under aseptic operation, and be placed in the prepared 10 - 15ml modified PBS tubes. All the samples cultivated 10 - 20 days in the PBS under 4℃ . Results Among 100 Marmota himalayana samples from Dege county, 2 strains of Yersinia enterocolitica were detected, and 1 Yersinia enterocolitica strain was screened from 148 samples from Ruoergai County. Conclusion The Himalayan marmots living in Sichuan westem plateau carry the Yersinia enterocolitica, and the symbiotic relationship possibly exists between Yersinia enterocolitica and Yersinia pestis.

  9. Investigation on rodents infection of Orientia tsutsugamushi in some areas of Nalati Grassland, Xinjiang Uygur Auto.Reg., China%新疆伊犁那拉提草原啮齿动物感染恙虫病东方体调查

    Institute of Scientific and Technical Information of China (English)

    党荣理; 任立松; 高金拽; 马德新; 刘晓明

    2011-01-01

    为了解新疆伊犁那拉提草原啮齿动物中自然感染恙虫病东方体(Ot)的情况,在那拉提草原捕获鼠和旱獭,分别取其脾组织提取DNA,应用巢式PCR(nPCR)方法检测Ot-Sta56基因;基因分型引物扩增阳性片段,判断该地区存在的Ot基因型,部分阳性标本测序,通过NCBI网站对序列进行BLAST比较分析.结果显示,在该地区共捕获鼠67只,旱獭29只,在其中3只鼠、2只旱獭的脾中检测到阳性片段,基因型包括Karp型、Saitama型,BLAST结果显示其中1个片段的核苷酸序列与Karp型同源性为97%,另1个片段未能测出核苷酸序列.推测在那拉提地区鼠类可能感染Ot,基因型为Karp型,怀疑可能有Saitama型存在.%DNAs were extracted from spleens of the rodents captured from Nalati area of Xinjiang Uygur Auto. Reg. , and nested-polymerase chain reaction ( nPCR ) was performed to detect the Orientia tsutsugamushi ( Ot )-Sta 56 gene. Some positive samples were sequenced and analyzed by BLAST of NCBI network. A total of 67 rodents and 29 marmots were captured in Nalati area. The positive fragments were detected from the spleens of 3 mice and 2 marmots , including Karp and Saitama genotype. The detection rates of Ot from Mus musculus, Cricetulus migratorius and Marmota barbacina were 6. 06%, 2. 94% and 6. 90% , respectively. The homology of one fragment of the amplified gene nucleotide sequence to Karp strain was 99% . The other fragments could not be sequenced. It was presumed that the Karp strain was the main gene type, and the Saitama strain might exist in this area.

  10. News from Online: A Spectrum of Color

    Science.gov (United States)

    Sweeney Judd, Carolyn

    1999-06-01

    Thomas Chasteen's site ( http://www.shsu.edu/~chm_tgc/sounds/sound.html) shows how to separate colors using a tuneable monochromator. This graphic comes from his monochromator animation ( http://www.shsu.edu/~chemistry/monochromator/mono.gif). Science Media's site ( http://www.scimedia.com/index.html#scimedia) includes spectroscopy tutorials by Brian Tissue. This graphic can be found at http://www.scimedia.com/chem-ed/light/graphics/em-rad.gif (©1998 B. M. Tissue, www.scimedia.com). All the colors in the rainbow! Now that is a good place to start. Go to About Rainbows ( http://www.unidata.ucar.edu/staff/blynds/rnbw.html), a tutorial from astronomer Beverly Lynds, working with the University Corporation for Atmospheric Research. The tutorial begins with a historical perspective, complete with a sketch by René Descartes in 1637. The bibliography makes this tutorial a good starting point for color exploration. About Rainbows brings you questions to explorefor example, "What happens when you look at a rainbow through dark glasses?" Try the links to these other sites. Project SkyMath: Making Mathematical Connections ( http://www.unidata.ucar.edu/staff/blynds/Skymath.html) is especially for the middle school student. Reproducible masters of these teaching modules can be printed in English and Spanish. From Project SkyMath, you can go to Blue-Skies, a user-friendly graphical interface from The Weather Underground at the University of Michigan ( http://groundhog.sprl.umich.edu/BS.html). And speaking of blue skies, look at a great site, Why is the Sky Blue at http://acept.la.asu.edu/PiN/act/sky/sky.shtml. This is a super site from the Arizona Collaborative for Excellence in the Preparation of Teachers, by the Department of Physics and Astronomy at Arizona State University. If you go to Patterns in Nature: Light and Optics at http://acept.la.asu.edu/PiN/act/activities.shtml, plan to spend some time, for it is wonderful. Another link from the About Rainbows tutorial goes to

  11. 黑龙江阿城交界洞穴遗址的哺乳动物群%PLEISTOCENE MAMMALIAN FAUNA FROM THE JIAOJIE CAVE AT ACHENG,HEILONGJIANG PROVINCE

    Institute of Scientific and Technical Information of China (English)

    于汇历; 董为

    2011-01-01

    The Jaiojie Paleolithic Site is located in a karstic cave at Acheng, Haerbin Municipality in Heilongjiang Province. It is regarded as the oldest Paleolithic site in the province and also the northernmost one in China up to today. The geographic coordination at the cave entrance measured with the Global Positioning System ( GPS) is 45°21'07. 7"N and 127°05'16. 8"E, with an altitude of 183m. The cave deposits can be divided into 6 layers. Mammalian fossils were unearthed mainly from Layers 5 and 6 in the lower part of the cave deposits. As a Quaternary mammalian fauna,it is chronologically the earliest one in Heilongjiang Province and geographically the northernmost and easternmost in China. Layer 5 is composed of grayish green clay with some yellow clods, and the underlying Layer 6 composed of reddish yellow clay with breccia. Although the site was discovered in 1996 and systematically excavated in 1997,the fossils were never systematically described before 12 taxa were identified as follow; Mar mot a sp., Myospalax cf. Prosilurus, Ochotona sp., Lepus ( Eulagos) mandshuricus ( = Lepus wongi) , Mattes sp., Meles meles, Mustela sibirica, Ursus sp, Crocuta sp., Stephanorhinus kirchbergensis ( = Dicerorhinus mercki) ,Cervus(S. )nippon hortulorum,Capreolus capreolus manehuricus. The fossils from Layer 5 are mostly smaller forms such as Marmota sp.,Myospalax cf.prosilurus,Lepus(Eulagos) mandshuricus( = Lepus wongi) ,etc. ,and those from Layer 6 are mostly larger forms such as Stephanorhinus kirchbergensis, Cervus ( Sika) hortulorum, Crocuta etc. They are mostly northern forms. The fauna lacks typical cold forms such as Coelodonta and Mammuthus, and it was regarded as a fauna exsiting during the transition from temperate period to cold one in North Region. The comparison of fauna compositions shows that the Jiaojie fauna is close to that of the Middle Pleistocene Jinniushan and Miaohoushan faunas in Liaoning Province, the Late Pleistocene Xiaogushan and Gulongshan faunas

  12. Para um Programa de Estudo do Neolítico em Portugal

    Directory of Open Access Journals (Sweden)

    Victor dos Santos GONÇALVES

    2009-10-01

    Full Text Available RESUMEN: El autor presenta, en líneas generales, los principales problemas de análisis del Neolítico en Portugal. Problemas que sólo en algunos casos son exclusivos del territorio portugués, ya que la mayor parte de ellos están ligados a la compleja evolución global del Neolítico en el Mediterráneo occidental. A continuación va a referirse a las propias dificultades intrínsecas para la definición de un concepto de Neolítico, e indica la escasez de información que todavía hoy existe a propósito del Neolítico portugués. Cita como ejemplo de las distorsiones provocadas por esta situación el caso de la cerámica cardial, escasa en el Neolítico antiguo portugués, donde abunda la cerámica incisa e impresa no cardial. En lo que se refiere al Neolítico antiguo, señala las principales estaciones encontradas hasta hoy en Portugal y alude más ampliamente a propósito de una, inédita el abrigo «das Bocas» (Rio Maior. A continuación, analiza las perspectivas con que se tendrá que abordar el fenómeno megalítico, planteando diversos problemas y enumerando las posibles acepciones para la palabra. Igualmente se refiere a la relación entre las inhumaciones en tres grutas localizadas en la región de Alcanena (la «Gruta dos Carrascos», la «Lapa da Galinha» y la «Gruta da Marmota» y una de las fases del megalitismo coincidente con el Neolítico medio. Sin embargo, como subraya el autor, únicamente un trabajo pluridisciplinar y de equipo podrá contribuir para obtener soluciones positivas a este problema.ABSTRACT: The Author presents an outline of the mam problems of the analysis of the Neolithic in Portugal. Problems that only in certain cases are exclusively found in Portuguese territory, since most of them are connected with the global evolution of the Neolithic in the Western Mediterranean. He refers the difficulties to found a definition for the concept of Neolithic and he points out the shortage of information that still

  13. El yacimiento de Lezetxiki (Gipuzkoa, País Vasco. Los niveles musterienses.

    Directory of Open Access Journals (Sweden)

    Amelia Baldeón

    1993-01-01

    pantera. El nivel III conoce oscilaciones climáticas que reflejan la sedimentología y los pólenes, presencia de fauna fría -rinoceronte lanudo, reno, marmota- y más templada -castor, ciervo, bisonte-. Hay restos de hogares y restos humanos atribuidos al hombre de Neanderthal. La industria no presenta ningún paralelismo con las facies clásicas y todos los datos apuntan a que bien los procesos tafonómicos o la complejidad en la identificación del depósito debido a los buzamientos cruzados del relleno (N-S y W-E impiden más precisiones. En este nivel se da un claro predominio del equipamiento musteriense -a nivel técnico y tipológico- con importante presencia de materiales netamente auriñacienses. Cierran la secuencia un nivel Gravetiense (el II y otro Magdaleniense Final (el I.

  14. The influence of sulfur and hair growth on stable isotope diet estimates for grizzly bears.

    Science.gov (United States)

    Mowat, Garth; Curtis, P Jeff; Lafferty, Diana J R

    2017-01-01

    Stable isotope ratios of grizzly bear (Ursus arctos) guard hair collected from bears on the lower Stikine River, British Columbia (BC) were analyzed to: 1) test whether measuring δ34S values improved the precision of the salmon (Oncorhynchus spp.) diet fraction estimate relative to δ15N as is conventionally done, 2) investigate whether measuring δ34S values improves the separation of diet contributions of moose (Alces alces), marmot (Marmota caligata), and mountain goat (Oreamnos americanus) and, 3) examine the relationship between collection date and length of hair and stable isotope values. Variation in isotope signatures among hair samples from the same bear and year were not trivial. The addition of δ34S values to mixing models used to estimate diet fractions generated small improvement in the precision of salmon and terrestrial prey diet fractions. Although the δ34S value for salmon is precise and appears general among species and areas, sulfur ratios were strongly correlated with nitrogen ratios and therefore added little new information to the mixing model regarding the consumption of salmon. Mean δ34S values for the three terrestrial herbivores of interest were similar and imprecise, so these data also added little new information to the mixing model. The addition of sulfur data did confirm that at least some bears in this system ate marmots during summer and fall. We show that there are bears with short hair that assimilate >20% salmon in their diet and bears with longer hair that eat no salmon living within a few kilometers of one another in a coastal ecosystem. Grizzly bears are thought to re-grow hair between June and October however our analysis of sectioned hair suggested at least some hairs begin growing in July or August, not June and, that hair of wild bears may grow faster than observed in captive bears. Our hair samples may have been from the year of sampling or the previous year because samples were collected in summer when bears were

  15. El medio ambiente durante el Pleistoceno Superior en la región Cantábrica con referencia especial a sus faunas de mamíferos.

    Directory of Open Access Journals (Sweden)

    Jesús Altuna

    1992-01-01

    Full Text Available Se examinan las asociaciones de Macromamíferos que han ido sucediéndose a lo largo del Pleistoceno Superior en el Pirineo Occidental y en el Cantábrico. Se inicia la serie con restos del   final del Riss, seguidos de otros del Eem, todos ellos escasos. Se poseen más datos del Würm antiguo, en el que hacen su presencia Coelodonta antiquitatis, Mammuthus primigenius y Rangifer tarandus en la cara N del Pirineo, pero solo esta última especie en el Cantábrico. La abundancia de caballo, bovinos y cabra unida a la consiguiente disminución del ciervo denota la implantación de biotopos abiertos, consecuencia del enfriamiento climático. Persisten sin embargo asociaciones anteriores con Dicerorhinus, Megaloceros, Ursus spelaeus, Panthera spelaea, etc. En la base del Würm III se observa todavía una gran abundancia de U. spelaeus, que va decreciendo claramente hasta quedar como especie residual. En este período se da la primera aparición en el Cantábrico de Mammuthus, Coelodonta, Alopex lagopus y Gulo gulo. Persisten Megaloceros, Dicerorhinus, Crocuta, Panthera pardus y Marmota, mientras se extingue P. spelaea. En su lugar aparece P. leo. Los bovinos y el caballo van descendiendo en abundancia, pero ello puede deberse a un cambio en las apetencias cinegéticas. Los atemperamientos de Laugerie-Lascaux parecen mantenerse, a juzgar por los análisis sedimentológicos, palinológicos y faunísticos de algunos de los niveles Solutrenses, y a pesar de algunas opiniones recientes en contra. El período Solutrense Cantábrico debió de conocer oscilaciones climáticas importantes. En el Würm IV se da una gran abundancia de ciervo y cabra junto a una escasez de bovinos, caballo y sarrio. En esta abundancia parece incidir de forma importante la especialización cinegética. Desaparecen Dicerorhinus y Megaloceros. Sigue presente el reno, al que acompaña Lepu timidus y desaparecen Gulo y Alopex. El mamut y el rinoceronte lanudo, que persisten en