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Sample records for gros morne national

  1. Boundary|Time|Surface: Art and Geology Meet in Gros Morne National Park, NL, Canada

    Science.gov (United States)

    Lancaster, Sydney; Waldron, John

    2015-04-01

    Environmental Art works range in scope from major permanent interventions in the landscape to less intrusive, more ephemeral site-specific installations constructed of materials from the local environment. Despite this range of intervention, however, these works all share in a tradition of art making that situates the artwork in direct response to the surrounding landscape. Andy Goldsworthy and Richard Long, for example, both favour methods that combine elements of both sculpture and performance in the creation of non-permanent interventions in the landscape, and both rely upon photographic, text-based, or video documentation as the only lasting indication of the works' existence. Similarly, Earth Scientists are responsible for interventions in the landscape, both physical and conceptual. For example, in Earth science, the periods of the geologic timescale - Cambrian, Ordovician, Silurian, etc. - were established by 19th century pioneers of geology at a time when they were believed to represent natural chapters in Earth history. Since the mid-20th century, stratigraphers have attempted to resolve ambiguities in the original definitions by defining stratotypes: sections of continuously deposited strata where a single horizon is chosen as a boundary. One such international stratotype, marking the Cambrian-Ordovician boundary, is defined at Green Point in Gros Morne National Park, Newfoundland. Boundary|Time|Surface was an ephemeral sculptural installation work constructed in June 2014. The main installation work was a fence of 52 vertical driftwood poles, 2-3 m tall, positioned precisely along the boundary stratotype horizon at Green Point in Newfoundland. The fence extended across a 150 m wave-cut platform from sea cliffs to the low-water mark, separating Ordovician from Cambrian strata. The installation was constructed by hand (with volunteer assistance) on June 22, as the wave-cut platform was exposed by the falling tide. During the remainder of the tidal cycle

  2. Highest national honour for CSIR President - (SABC Morning Live Interview)

    CSIR Research Space (South Africa)

    Sibisi, S

    2007-09-26

    Full Text Available Buildings, to admit some exceptional persons to the Order of Mapungubwe. These are people whose activities cannot but be described as excellent. They are the men and women who dared to act outside the boundaries of the ordinary, taking upon themselves...! On this day, let all citizens and patriots proclaim: Glory to the Honoured Members of the National Orders! God Bless Africa! Save her children! Grant her peace! Enquiries: Mukoni Rashitanga on 082 300 3447 Issued by GCIS on behalf of the Presidency ...

  3. Morning Star

    OpenAIRE

    Harris, Mark

    2010-01-01

    Morning Star comprises a group of paintings and drawings whose imagery derives from photographs of 1960s American hippie communes. The paintings are made using oil paint on linen. Their dimensions vary between 180 x 120, and 228 x 217 centimetres. The drawings are in pencil on watercolour paper and are all 56 x 76 centimetres. The work has been exhibited in conventional form, hanging on gallery walls. For Morning Star I made pencil drawings and oil paintings derived from images in Dick Fa...

  4. Morning sickness (image)

    Science.gov (United States)

    Morning sickness usually begins during the first month of pregnancy and continues until the 14th to 16th week. ... have nausea and vomiting through their entire pregnancy. Morning sickness is very common and does not hurt the ...

  5. Morning-After Pill

    Science.gov (United States)

    ... and within 120 hours. You can take emergency contraceptive pills anytime during your menstrual cycle. To use the ... to five weeks after taking the morning-after pill, contact him or her. These may ... B One-Step emergency contraceptive for use without a prescription for all women ...

  6. Drizzly Mornings on Xanadu

    Science.gov (United States)

    2007-10-01

    Morning forecast on Saturn's moon Titan with ESO's VLT Noted for its bizarre hydrocarbon lakes and frozen methane clouds, Saturn's largest moon, Titan, also appears to have widespread drizzles of methane, according to a team of astronomers at the University of California, Berkeley. New near-infrared images from ESO's Very Large Telescope (VLT) in Chile and the W. M. Keck Observatory in Hawaii show for the first time a nearly global cloud cover at high elevations and, dreary as it may seem, a widespread and persistent morning drizzle of methane over the western foothills of Titan's major continent, Xanadu. ESO PR Photo 47/07 ESO PR Photo 47/07 Drizzly Mornings on Titan In most of the Keck and VLT images, liquid methane clouds and drizzle appear at the morning edge of Titan, the arc of the moon that has just rotated into the light of the sun. "Titan's topography could be causing this drizzle," said Imke de Pater, member of the team that made the discovery. "The rain could be caused by processes similar to those on Earth: moisture laden clouds pushed upslope by winds condense to form a coastal rain." Lead author Máté Ádámkovics noted that only areas near Xanadu exhibited morning drizzle, and not always in the same spot. Depending on conditions, the drizzle could hit the ground or turn into a ground mist. The drizzle or mist seems to dissipate after local mid-morning, which, because Titan takes 16 Earth days to rotate once, is about three Earth days after sunrise. "Maybe only Xanadu has misty mornings," he said. Ádámkovics first saw evidence of widespread, cirrus-like clouds and methane drizzle when analysing data taken on 28 February 2005 from a new instrument on the VLT - the Spectrograph for INtegral Field Observations in the Near Infrared (SINFONI). Further images and spectra taken on April 17, 2006, by the OH-Suppressing Infra-Red Imaging Spectrograph (OSIRIS) on Keck II confirmed the clouds. Both instruments measure spectra of light at many points in an

  7. Morning and evening exercise

    Directory of Open Access Journals (Sweden)

    Dae Yun Seo

    2013-12-01

    Full Text Available A growing body of evidence suggests that exercise may contribute to preventing pathological changes, treating multiple chronic diseases, and reducing mortality and morbidity ratios. Scientific evidence moreover shows that exercise plays a key role in improving health-related physical fitness components and hormone function. Regular exercise training is one of the few strategies that has been strictly adapted in healthy individuals and in athletes. However, time-dependent exercise has different outcomes, based on the exercise type, duration, and hormone adaptation. In the present review, we therefore briefly describe the type, duration, and adaptation of exercise performed in the morning and evening. In addition, we discuss the clinical considerations and indications for exercise training.

  8. Gros temps

    Directory of Open Access Journals (Sweden)

    Jean Marie Théodat

    2008-10-01

    Full Text Available Ce sixième cahier paraît à un moment où « l’immense orgue des vents grondeurs » cher à Baudelaire fait rage dans les finances du pays le plus puissant de la planète. Les turbulences provoquées par l’explosion de la bulle financière américaine entraînent un déséquilibre mondial qui va demander des réajustements structurels et profonds dans le modèle de développement du pays le plus riche. Les fondements même de l’économie libérale se trouvent ébranlés dans le pays qui en a fait son credo et so...

  9. Discipline and credibility in the post-war australopithecine controversy: Le Gros Clark versus Zuckerman.

    Science.gov (United States)

    Richmond, Jesse

    2012-01-01

    Paleoanthropologists and outside commentators have often remarked upon the apparent difficulty of securing shared belief among experts in the science of human evolution. The field has been and continues to be particularly prone to disagreement and even controversy among its practitioners to a degree that sets it apart from other areas of scientific inquiry. The fact that the field lies at the intersection of a number of disciplines may help to explain this predicament. Displays of discipline serve as an important resource for scientists as they work to secure credibility. Where a field of inquiry spans a host of disciplinary approaches, there can be disagreement about the kind of disciplined behavior appropriate to making credible claims about that field's subject matter. A conflict of this sort emerged after WW II over the claim that the australopithecines of South Africa represented a likely ancestral link in the evolution of human beings. W. E. Le Gros Clark, working in the established disciplinary tradition of comparative anatomy, endorsed the claim of ancestry, while Solly Zuckerman, reflecting his recent immersion in war-time operations research, criticized that claim on the grounds that it came without the rigorous quantitative demonstration that he felt was the hallmark of a properly disciplined science.

  10. Socialization at the morning meeting

    DEFF Research Database (Denmark)

    Rimestad, L.; Gravengaard, Gitte

    2016-01-01

    In this ethnographic study we examine how journalism interns present ideas at morning meetings in the professional environment of a media organization. We analyse not only the idea presentation at the meeting itself, but also how editors treat the idea presentation, and how the interns perceive...

  11. Morning Receptions in a Danish ECE Context

    DEFF Research Database (Denmark)

    Kornerup, Ida; Gravgaard, Mette Lykke

    2017-01-01

    This paper focus on a special pedagogical context; morning receptions as a learning environment. The studies of mornings are part of a 3 year long research project in which different types of learning environments were investigated. Few studies have researched morning receptions in this perspecti...

  12. Differential response of pitted morning glory and ivy leaf morning glory to acifluorfen, fomesafen, and lactofen

    Energy Technology Data Exchange (ETDEWEB)

    Higgins, J.M.

    1987-01-01

    Field and laboratory investigations were conducted to examine the response of soybeans (Glycine max (L.) Merr.), pitted morning glory (Ipomoea lacunosa L.number/sup 1/ IPOLA), and ivy leaf morning glory (Ipomoea hederacea (L.) Jacq. number IPOHE) to acifluorfen, fomesafen, and lactofen. In field studies, greatest soybean injury was observed with acifluorfen and lactofen. All treatments provided 80% or greater control of pitted morning glory 15 days after treatment. Only acifluorfen and fomesafen at 0.6 kg ai ha/sup -1/ provided 80% or greater ivy leaf morning glory. The differential response of pitted morning glory and ivy leaf morning glory to these diphenyl ether herbicides was reflected in soybean seed yields. In laboratory studies, 71 to 84% of applied /sup 14/C-acifluorfen was not absorbed into the leaf surface of ivy leaf morning glory. Thirty-two to 46% of applied acifluorfen was recovered from the leaf surface of pitted morning glory. Sixty-four percent of applied /sup 14/C-lactofen was recovered from leaf surfaces of both morning glory species 96 h after treatment. Treated leaves of pitted morning glory contained 35 to 37% more /sup 14/C-acifluorfen than ivy leaf morning glory. Less than 28% of applied /sup 14/C-lactofen was absorbed into treated leaves of both morning glory species at 24, 48, and 96 h harvests.

  13. AAS 228: Day 3 morning

    Science.gov (United States)

    Kohler, Susanna

    2016-06-01

    massive disks, which in turn produce more gas giants, populating our surveys with such planets.Dr. Knutson shows that ~50% of hot Jupiters have long distance companions.Morning Press Conference Latest News from the LIGO Scientific Collaboration (by Michael Zevin)On December 26th 2015, LIGO detected its second full-fledged gravitational wave event, dubbed GW151226 (the numbers signify the date it was detected). This detection along with the full results ofLIGOs first observing run wereannounced byGabriela Gonzlez, David Reitze, and Fulvio Ricci in the morning press conference. The masses of the two black holes are smaller than those of the first confirmed event (GW150914) about 8 14 solar masses for GW151226 compared to 29 36 solar masses for GW150914. Though less visible by eye in the data, sophisticated search algorithms that match theoretically-produced templates of the gravitational waveform were able to extract it from the data and build up enough statistical confidence to declare it as a detection. The system was estimated to have merged at a distance of 1.4 billion light-years, and, due to its lower mass, stayed in LIGOs detection band for a full second (5 times longer than the more massive GW150914).Time-frequency plot of the second confirmed gravitational waveevent GW151226. Light colors represent higher energy.This discovery further solidifies this nascent field into astronomy, and has given astronomers a new sense to explore the Universe. The next observing run of LIGO will commence later in 2016 and will be more sensitive due to system upgrade, increasing the rate at which LIGO should detect these types of astrophysical events. In addition, more detectors will be joining the network of gravitational wave observatories over the next few years, which will further constrain the location at which these events occur in the cosmos and increase the likelihood of detecting an electromagnetic counterpart to a gravitational wave event. More great discoveries to come

  14. AAS 228: Day 2 morning

    Science.gov (United States)

    Kohler, Susanna

    2016-06-01

    extremely data-rich. The Galaxy Zoo project also suggests the promising prospect of synergizing the help from citizen scientists and machine learning in analyzing extremely large datasets.Extrasolar Planets: Atmospheres (by Leonardo dos Santos)Antonija Oklopi (Caltech) explains that Raman scattering of light, which works similarly to Rayleigh scattering (the process that makes Earths sky blue), can be used in the future to study the atmospheres of exoplanets. Her work is to create model spectra containing these features, from which we can learn about the presence and altitude of atmospheric clouds. Dr. Carl Melis (University of California, San Diego) studies the inner composition of exoplanets by looking at their remnants after they are destroyed by a dying star. His most recent work suggests that there is a differentiated pollution (from the core and the crust of a planet) in the disk orbiting of a white dwarf star. Samuel Grunblatt (University of Hawaii) introduces us to the main subject of his thesis: a hot-Jupiter observed by Keplers K2 mission transiting an evolved, red giant star. They used some pretty tricky data analysis in order to filter out the noise intrinsic to this type of star.Grunblatt shows the K2 transit before and after removal of granulation effects.Avi Shporer (JPL) asks the question: why are hot Jupiters so large? His research aims to study the correlation between stellar irradiation and planetary radius, and in order to have a more complete picture, they need to detect more gas giants on lower stellar irradiation regions. This idea gave rise to LCOGT K2 Warm Jupiter project, which recently discovered a brown dwarf in a long-period orbit around a Sun-like star. Paul Mason (New Mexico State University) proposes that the Milky Way is evolving to a more habitable galaxy, due to the expansion of the universe, the processing of heavier material inside stars, and the general decrease of ionizing radiation.Evolution of Galaxies (by Ben Cook)Tuesday mornings

  15. AAS 228: Day 1 morning

    Science.gov (United States)

    Kohler, Susanna

    2016-06-01

    Editors Note:This week were at the 228th AAS Meeting in San Diego, CA. Along with a team ofauthors from astrobites.com, I will bewritingupdates on selectedevents at themeeting and posting twiceeach day. Follow along here or atastrobites.com, or catch ourlive-tweeted updates from the@astrobites Twitter account. The usual posting schedule for AAS Nova will resumenext week.Come visit astrobites at the AAS booth we have swag!Things kicked off last night at our undergraduate reception booth. Thanks to all of you who stopped by we were delightedto hear from undergrads who already know and love the site, educators who want to use it in their classrooms, and students who had not yet been introduced to astrobites and were excited about a new resource!For the rest of the meeting we will be stationed at theAAS booth in the exhibit hall (booth #211-213), so drop by if you want to learn more (or pick up swag: weve got lots of stickers and sunglasses)!Mondaymorning was the official start of the meeting. Here are just a few of the talks and workshops astrobiters attended this morning.Opening Address(by Susanna Kohler)AAS President Meg Urry kicked off the meeting this morning at 8am with an overview of some of the great endeavors AAS is supporting. We astrobiters had personal motivation to drag ourselves out of bed that early: during this session, Urryannounced the new partnership between AAS and astrobites!Urry touched on some difficult topics in her welcome, including yesterdays tragedy in Orlando. Shereiteratedthe AASs support fortheCommittee for Sexual-Orientation and Gender Minorities in Astronomy (SGMA). She also reminded meeting attendees about the importance ofkeeping conference interactions professional, and pointed to the meetings anti-harassment policy.Partnership Announcement (by Michael Zevin)This morning, the American Astronomical Society announced the new partnership that it will have with Astrobites! We are beyond excited to embark on this new partnership with the

  16. Morning or evening administration of nasal calcitonin?

    DEFF Research Database (Denmark)

    Schlemmer, A; Ravn, Pernille; Hassager, C;

    1997-01-01

    The purpose of this study was to examine the effect of intranasal salmon calcitonin (sCT) administration (200 IE), given either in the morning (8:00) or evening (21:00), on the known circadian variation in biochemical markers of bone turnover. An open, placebo-controlled, randomized, crossover......). Serum osteocalcin (sOC) was measured by radioimmunoassay (RIA). The first 24 h study was performed without intervention. Prior to this control study the participants were randomized to either morning (8:00) or evening (21:00) sCT (200 IE). sCT administrations were given 4-5 days prior to and during...... in late afternoon. Both morning and evening administration of sCT significantly decreased the urinary excretion of CrossLaps/Cr approximately 3-6 h after administration with a subsequent rebound effect. sOC did not exhibit a significant circadian variation and was not affected by the calcitonin. The 24 h...

  17. The Language of the Saturday Morning Ghetto.

    Science.gov (United States)

    McCorkle, Suzanne

    A content analysis was conducted to assess the verbal climate of Saturday morning television programs, the types of verbal aggression that appear in them, and the way verbal responses relate to other program variables. Three content analysis tools were developed and applied to ten half-hour program blocks drawn randomly from the regularly…

  18. Morning Exercises are Good to Your Health

    Institute of Scientific and Technical Information of China (English)

    JENNIFER LIM

    1997-01-01

    EARLY to rise, many Chinese leave their homes and head for the streets or lanes in twos and threes to open areas by lakes, rivers or woods.Without command or guidance,people take part in morning exercises completely out of their own free wills and keep on it day by day.

  19. Caracterización de harina y almidón de frutos de banano Gros Michel (Musa acuminata AAA

    Directory of Open Access Journals (Sweden)

    Jairo Montoya-López

    2015-01-01

    Full Text Available En el estudio se determinaron las características fisicoquímicas, térmicas y reológicas de la harina y el almidón de frutos de banano Gros Michel (Musa acuminata cosechado en fincas del departamento del Quindío, Colombia. En el análisis proximal, la harina presentó un contenido de fibra de 18.82% y el almidón presentó contenidos de proteína de 1.92%, grasa de 5.3% y fibra de 2.76%. La harina presentó la temperatura más alta de absorción de calor (68.88 °C y su entalpía de gelatinización fue de 2.17 J/g; mientras que para el almidón estos valores fueron de 48.36 °C y 44.62 J/g, respectivamente. El análisis termogravimétrico (TGA de la harina o temperaturas en las cuales se registra la descomposición de carbohidratos (componentes de bajo peso molecular y polisacáridos (componentes de alto peso molecular fueron, respectivamente, de 284.51 °C y 470.42 °C; y para el almidón fueron de 307.51 °C y 500.46 °C. Los gránulos de almidón de banano tienen forma elipsoidal con un tamaño longitudinal promedio de 39.39 µm y tamaño transversal promedio de 29.47 µm. Los difractogramas de rayos X mostraron patrones de difracción tipo B. Los viscoamilogramas mostraron que para la harina la temperatura de inicio de gelatinización (Tg es de 76.3 °C, la viscosidad máxima de 1120 cP, y para el almidón la Tg fue de 70.75 °C y la viscosidad máxima de 2087 cP.

  20. Morning glory disc anomaly with Chiari type I malformation.

    Science.gov (United States)

    Arlow, Tim; Arepalli, Sruthi; Flanders, Adam E; Shields, Carol L

    2014-04-30

    Morning glory disc anomaly is a rare optic nerve dysplasia associated with various neovascular abnormalities. Due to these associations, children with morning glory disc anomaly have brain imaging and angiography to detect other congenital defects. The authors report the case of an infant with morning glory disc anomaly and coexisting Chiari type I malformation.

  1. Morning sickness: impact on offspring salt preference.

    Science.gov (United States)

    Crystal, S R; Bernstein, I L

    1995-12-01

    These studies examined the relationship between salt preference of adult offspring and their mothers' symptoms of morning sickness during pregnancy. College students who could provide information about their mothers' symptoms of morning sickness completed a survey about their dietary salt intake (study 1; n = 169) or rated and consumed ten snack foods (study 2; n = 66). In study 1 a salt-use score was calculated based on responses to the Salt Intake Questionnaire; offspring of women with moderate or severe vomiting reported a significantly higher level of salt use (p < 0.01) than those whose mothers report little or no symptoms. In study 2 saltiness and pleasantness ratings of high-salt foods, intake of those foods and total sodium intake were the focus of analysis. Offspring of women reporting moderate or severe vomiting showed a significantly greater preference for the snack food subjects rated as saltiest than those whose mothers reported no or mild vomiting. They also ate more of that food and consumed more total sodium during the test session. Effects were stronger in Caucasian than Asian subjects. These studies suggest that moderate to severe vomiting during pregnancy can be associated with significantly higher salt intake in offspring. Thus, a gestational event may be an important determinant of salt intake and preference in adulthood.

  2. Modificação do método de Bielschowsky-Gros para cortes em parafina

    Directory of Open Access Journals (Sweden)

    José Fernandez

    1958-03-01

    Full Text Available É proposta uma modificação para o método de Bielschowsky-Gros a ser aplicado em cortes em parafina, utilizável no estudo de terminações nervosas centrais e periféricas. O método é de manipulação fácil e executável em poucas horas, ao contrário da grande maioria de métodos de impregnação em cortes de parafina. A impregnação é precedida de preparador e de mordente e seguida por viragem em ouro. O preparador utilizado é a solução de formol a 2% neutralizada com carbonato de magnésio, adicionada ou não a sonifeno a 1% O emprêgo do sonifeno tem a vantagem de permtir impregnar mais vigorosamente as fibras e terminações nervosas e evitar ao máximo a impregnação das fibras conjuntivas, oferecendo perfeita limpeza da preparação. O mordente é constituído por uma solução recente de nitrato de prata a 10% na qual os cortes permanecem por tempo variável, sendo aconselhável, para a coloração do plexo simpático fundamental, permanência prolongada (cêrca de uma hora. A impregnação é feita em solução de óxido de prata amoniacal preparada como o recomenda Bielchowsky (solução de nitrato de prata a 10% acrescida de amoníaco até completa dissolução do precipitado formado, podendo ser substituída, com idênticos resultados, pelas soluções propostas por Rio-Hortega, Foot, Arteta e Jabonero. A viragem em ouro é feita utilizando a solução aconselhada por Castro (uma gota de ácido acético para cada 10ml de solução de cloreto de ouro amarelo a 1/600. Os resultados obtidos com o método proposto são satisfatórios. Conseguiu-se impregnar com perfeição neurônios do gânglio de Gasser; nas preparações com sonifeno, as fibras nervosas e os prolongamentos celulares apareciam perfeitamente impregnados e a preparação oferecia limpeza absoluta. No apêndice cecal as terminações nervosas resultavam perfeitamente impregnadas, contrastando, principalmente quando foi empregado o sonifeno, com os elementos

  3. Morning glory syndrome associated with multiple sclerosis.

    Directory of Open Access Journals (Sweden)

    Anahid Safari

    2014-09-01

    Full Text Available Morning glory syndrome (MGS is a rare congenital optic disc anomaly characterized by a funnel-shaped, excavated optic disc surrounded by chorioretinal pigmentary disturbance. The main ophthalomoscopic feature of the MGS is enlarged optic disc with a funnel shaped scleral defect; elevated peripapillary chorioretinal pigmentation; and pale fluffy tissue of glial hyperplasia overlying the optic disc. Although most of the reported cases were isolated ocular abnormality, but it may occurs in association with other ophthalmic abnormalities such as cyst of the optic nerve atrophy, congenital cataract, microophthalmos, and aniridia. Craniofacial deformities such as cleft lip and palate, hypertelorism, dysplatic ears; renal abnormalities; and cardiac defects have also been reported with MGS. Herein, we present a case of MGS associated with multiple sclerosis - a rather unusual concurrence.

  4. P6 acupressure reduces morning sickness.

    Science.gov (United States)

    Dundee, J W; Sourial, F B; Ghaly, R G; Bell, P F

    1988-08-01

    A prospective study was designed to test the efficacy of pressure at the P6 (Neiguan) acupuncture point, in preventing morning sickness. Three groups of patients in early pregnancy recorded the severity and frequency of sickness over a period of 4 consecutive days following daily pressure at P6 point, pressure at a point near the right elbow and with no treatment. Troublesome sickness was significantly less in both the genuine (23/119) and dummy (41/112) pressure groups as compared with the control series (67/119). When the data are adversely 'weighted' to compensate for the lower incidence of fully completed returns in the active treatment groups, only the P6 group show a significant reduction in sickness. No side effects occurred in either group and while anticipation of benefit may offer a partial explanation for the findings, pressure at the Neiguan point appears to have a specific therapeutic effect.

  5. Understanding "Morning Girl" through Judith Langer's "Envisionment" Model.

    Science.gov (United States)

    Tuleja, Elizabeth A.

    1998-01-01

    Relates the author's own experience of reading "Morning Girl," by Michael Dorris, as an example of practicing literary criticism. Provides an in-depth analysis of "Morning Girl" and how it could be interpreted and discussed through Langer's model of envisionment building. Illuminates Langer's theory so that it may be applied to…

  6. Morning sickness and vitamin B6 status of pregnant women.

    Science.gov (United States)

    Schuster, K; Bailey, L B; Dimperio, D; Mahan, C S

    1985-01-01

    The relationship between the vitamin B6 status of 180 pregnant women and the incidence and degree of morning sickness experienced during the first trimester was investigated. There were no significant differences in plasma pyridoxal 5'-phosphate (PLP), erythrocyte aspartate aminotransferase (AspAT) activity, and stimulation of erythrocyte AspAT activity by exogenous PLP between subjects who experienced morning sickness and those who did not. No relationship was found between these indicators of vitamin B6 status and the degree of morning sickness experienced by this group during early pregnancy. There were no differences in the number of women who experienced morning sickness or in the number with different degrees of sickness when plasma levels of PLP, erythrocyte AspAT activity or stimulation by PLP were divided into upper and lower 50th percentile groups and compared. Therefore these data show no relationship between vitamin B6 status and the incidence or degree of morning sickness.

  7. Changing Morning Report: An Educational Intervention to Address Curricular Needs

    Directory of Open Access Journals (Sweden)

    Vijay John Daniels

    2014-01-01

    Full Text Available Morning report is a case-based teaching session common to many residency programs with varying purposes and focuses. At our institution, physicians and residents felt our Internal Medicine morning report had lost its educational focus. The purpose of this project was to improve morning report using a well-known curriculum development framework for medical education. We conducted a focus group of residents to develop and implement changes to morning report. Themes from our focus group led us to split morning report with the first 30 minutes for postgraduate year 3 (PGY-3 residents to give handover, to receive feedback on diagnosis and management, and to either discuss an interesting case or receive teaching aimed at their final certification examination. The second 30 minutes involved PGY-3 residents leading PGY-1 residents in case-based discussions with an attending physician providing feedback on the content and process of teaching. We measured success based on a follow-up survey and comments from resident evaluations before and after the change. Overall, the changes were well received by both faculty and residents; however comments revealed that the success of morning report is preceptor dependent. In summary, we have successfully implemented a split morning report model to enhance resident education with positive feedback.

  8. Duane's retraction syndrome associated with morning glory syndrome.

    Science.gov (United States)

    Kawano, K; Fujita, S

    1981-01-01

    A 9-year-old boy with Duane's retraction syndrome and morning glory syndrome is presented. The right eye showed a grayish-pink optic disc, which had a deep excavation containing a white mass in its center and was surrounded by an annulus of pigment disturbance, i.e., consistent with the features of morning glory syndrome. The left eye had a congenital disturbance of ocular motility, which was typical of Duane's retraction syndrome. This is probably the first report of the association of Duane's retraction syndrome and morning glory syndrome. It is hypothesized that a noxious stimulus given at around two months of gestation was responsible for this rare association.

  9. Physiological changes, sleep, and morning mood in an isolated environment

    Science.gov (United States)

    Kraft, Norbert O.; Inoue, Natsuhiko; Mizuno, Koh; Ohshima, Hiroshi; Murai, Tadashi; Sekiguchi, Chiharu; Orasanu, J. M. (Principal Investigator)

    2002-01-01

    BACKGROUND: Previous isolation studies have shown increased 24-h urine volumes and body weight gains in subjects. This project examined those and other physiological variables in relationship to sleep motor activity, subjective sleep quality, mood, and complaints during confinement. METHODS: Six male and two female subjects lived for 7 d in the National Space Development Agency of Japan's isolation chamber, which simulates the interior of the Japanese Experiment Module. Each 24-h period included 6 h of sleep, 3 meals, and 20 min of exercise. Each morning, subjects completed Sleep Sensation and Complaint Index questionnaires. Catecholamine and creatinine excretion, urine volume, and body weight were measured on the 2 d before and 2 d after confinement, and sleep motor activity was measured during confinement. RESULTS: Confinement produced no significant change in body weight, urine volume, or questionnaire results. In contrast, epinephrine, norepinephrine, and sleep motor activity exhibited significant differences during confinement (p < 0.05). Higher nocturnal norepinephrine excretion correlated with higher sleep motor activity. CONCLUSION: The 24-h epinephrine values were slightly higher than normal throughout the experiment, but lower than for subjects working under time-stress. High sympathetic activity (as indicated by norepinephrine) may have interfered with sleep.

  10. Diclectin for morning sickness: Long-term neurodevelopment.

    Science.gov (United States)

    Nulman, Irena; Koren, Gideon

    2011-02-01

    Question A pregnant patient recently asked me whether using Diclectin for morning sickness might affect the development of her child. Answer Our recent large study does show such a trend, although the differences are not necessarily clinically significant.

  11. Comparison of morning and afternoon exercise training for asthmatic children

    Directory of Open Access Journals (Sweden)

    C.S. Silva

    2006-01-01

    Full Text Available Fitness improvement was used to compare morning with afternoon exercise periods for asthmatic children. Children with persistent moderate asthma (according to GINA criteria, 8 to 11 years old, were divided into 3 groups: morning training group (N = 23, afternoon training group (N = 23, and non-training group (N = 23. The program was based on twice a week 90-min sessions for 4 months. We measured the 9-min running distance, resting heart rate and abdominal muscle strength (sit-up number before and after the training. All children took budesonide, 400 µg/day, and an on demand inhaled ß-agonist. The distance covered in 9 min increased (mean ± SEM from 1344 ± 30 m by 248 ± 30 m for the morning group, from 1327 ± 30 m by 162 ± 20 m for the afternoon group, and from 1310 ± 20 m by 2 ± 20 m for the control group (P 0.05 for morning with afternoon comparison. The reduction of resting heart rate from 83 ± 1, 85 ± 2 and 86 ± 1 bpm was 5.1 ± 0.8 bpm in the morning group, 4.4 ± 0.8 bpm in the afternoon group, and -0.2 ± 0.7 bpm in the control group (P > 0.05 for morning with afternoon comparison and P 0.05 for morning with afternoon comparison and P < 0.05 versus control. No statistically significant differences were detected between the morning and afternoon groups in terms of physical training of asthmatic children.

  12. Creating Modern Japanese Subjects: Morning Rituals from Norito to News and Weather

    Directory of Open Access Journals (Sweden)

    Wilburn Hansen

    2016-03-01

    Full Text Available This original research on Restoration Shinto Norito seeks to explain the rhetorical devices used in the composition of a morning prayer ritual text. The nativist scholar, Hirata Atsutane, crafted this ritual to create a Japanese imperial subject with a particular understanding of native identity and national unity, appropriate to the context of a Japan in the shadow of impending modernity and fear of Western domination. The conclusions drawn concerning Hirata’s rhetoric are meant to inform our understanding of the technique and power of the contemporary Japanese morning television viewing ritual used to create post-modern Japanese citizens with an identity and unity appropriate to a global secular context.

  13. Food advertisements during children's Saturday morning television programming: are they consistent with dietary recommendations?

    Science.gov (United States)

    Kotz, K; Story, M

    1994-11-01

    Children in the United States spend more time watching television than they do in any other activity except sleep. Given the number of food commercials to which children are exposed, we thought it would be of interest to examine current food advertising during children's television programs and to assess whether the products advertised are consistent with dietary recommendations for good health. The 52.5 hours of children's Saturday morning television we viewed from five major networks contained 997 commercials selling a product and 68 public service announcements. Of the 564 food advertisements (56.5% of all advertisements), 43.6% advertised foods classified in the fats, oils, and sweet food group. The most frequently advertised product was high-sugar cereals. We found that commercials broadcast during children's Saturday morning programming promote foods predominantly high in fat and/or sugar, many of which have relatively low nutritional value. As such, the diet presented on Saturday morning television is the antithesis of what is recommended for healthful eating for children. We conclude that the issue of television food advertising to young children be revisited on a national level.

  14. Spot or early morning sample for mycobacterial culture: which?

    Science.gov (United States)

    Das, D; Dwibedi, B; Kar, S K

    2014-03-01

    Drug resistance studies ideally require two sputum specimens, one spot and one early morning, for culture in Löwenstein-Jensen medium. Although the type of specimen plays a major role in the detection of acid-fast bacilli using microscopy, this type of specimen collection puts unnecessary pressure on patients. Two sputum samples, one on the spot and another in the early morning, collected from 179 TB patients in cetylpyridinium chloride and processed for culture, yielded respectively 89.9% and 87.7% culture positivity, while culture positivity increased to 93.3% when both specimens were tested.

  15. Morning sickness: a mechanism for protecting mother and embryo.

    Science.gov (United States)

    Flaxman, S M; Sherman, P W

    2000-06-01

    Approximately two-thirds of women experience nausea or vomiting during the first trimester of pregnancy. These symptoms are commonly known as morning sickness. Hook (1976) and Profet (1988) hypothesized that morning sickness protects the embryo by causing pregnant women to physically expel and subsequently avoid foods that contain teratogenic and abortifacient chemicals, especially toxic chemicals in strong-tasting vegetables, caffeinated beverages and alcohol. We examined this hypothesis by comprehensively reviewing the relevant medical, psychological and anthropological literature. In its support, (i) symptoms peak when embryonic organogenesis is most susceptible to chemical disruption (weeks 6-18), (ii) women who experience morning sickness are significantly less likely to miscarry than women who do not (9 of 9 studies), (iii) women who vomit suffer fewer miscarriages than those who experience nausea alone, and (iv) many pregnant women have aversions to alcoholic and nonalcoholic (mostly caffeinated) beverages and strong-tasting vegetables, especially during the first trimester. Surprisingly, however, the greatest aversions are to meats, fish, poultry, and eggs. A cross-cultural analysis using the Human Relations Area Files revealed 20 traditional societies in which morning sickness has been observed and seven in which it has never been observed. The latter were significantly less likely to have animal products as dietary staples and significantly more likely to have only plants (primarily corn) as staples than the 20 societies in which morning sickness occurred. Animal products may be dangerous to pregnant women and their embryos because they often contain parasites and pathogens, especially when stored at room temperatures in warm climates. Avoiding foodborne microorganisms is particularly important to pregnant women because they are immunosuppressed, presumably to reduce the chances of rejecting tissues of their own offspring (Haig 1993). As a result

  16. Morning and Night People in the Family: A Preliminary Statement

    Science.gov (United States)

    Adams, Bert N.; And Others

    1978-01-01

    This paper is a preliminary statement about morning and night people. The authors collected and analyzed married student responses to open-ended questions concerning "morningness" and "nightness" as factors influencing individual, marital, and family adjustment. This issue has both theoretical and practical significance for marriage and the…

  17. Team Teaching in the Saturday Morning Search for Solutions.

    Science.gov (United States)

    Solomon, Pearl G.; And Others

    The Marie Curie Mathematics and Science Center at St. Thomas Aquinas College (New York), in a comprehensive effort to improve mathematics and science education, offers the Saturday Morning Search for Solutions enrichment program for area students in grades 7-12. The program is interdisciplinary, connecting technology and the study of societal…

  18. Suppressing the Morning Rise in Cortisol Impairs Free Recall

    Science.gov (United States)

    Rimmele, Ulrike; Meier, Flurina; Lange, Tanja; Born, Jan

    2010-01-01

    Elevated glucocorticoid levels impair memory retrieval. We investigated whether retrieval under naturally elevated glucocorticoid levels, i.e., during the morning rise in cortisol can be improved by suppressing cortisol. In a crossover study 16 men retrieved emotional and neutral texts and pictures (learned 3 d earlier) 30 min after morning…

  19. Suppressing the Morning Rise in Cortisol Impairs Free Recall

    Science.gov (United States)

    Rimmele, Ulrike; Meier, Flurina; Lange, Tanja; Born, Jan

    2010-01-01

    Elevated glucocorticoid levels impair memory retrieval. We investigated whether retrieval under naturally elevated glucocorticoid levels, i.e., during the morning rise in cortisol can be improved by suppressing cortisol. In a crossover study 16 men retrieved emotional and neutral texts and pictures (learned 3 d earlier) 30 min after morning…

  20. Morning Star Students: A Follow-up Study.

    Science.gov (United States)

    Sloan, Leroy V.

    Findings of two followup studies of Morning Star (a 2-year Native teacher education program established in 1975 at the Blue Quills Native Education Centre, leading to a Bachelor of Education degree from the University of Alberta) are examined in relation to the program's assumptions, organization, and delivery systems. The teacher certification of…

  1. Morning Star Cycle Two: Follow-up Study.

    Science.gov (United States)

    Sloan, L. V.

    Semi-structured telephone interviews were used to gather follow-up data on students who completed the 1977-1979 Morning Star cycle two program, a community-based Native teacher education program at the Blue Quills Native Education Centre leading to a Bachelor of Education degree from the University of Alberta. Of the 24 students who completed…

  2. Morning versus evening induction of labour for improving outcomes.

    Science.gov (United States)

    Bakker, Jannet J H; van der Goes, Birgit Y; Pel, Maria; Mol, Ben Willem J; van der Post, Joris A M

    2013-02-28

    Induction of labour is a common intervention in obstetric practice. Traditionally, in most hospitals induction of labour with medication starts early in the morning, with the start of the working day for the day shift. In human and animal studies spontaneous onset of labour is proven to have a circadian rhythm with a preference for start of labour in the evening. Moreover, when spontaneous labour starts in the evening, the total duration of labour and delivery shortens and fewer obstetric interventions are needed. Based on these observations one might assume that starting induction of labour in the evening, in harmony with the circadian rhythm of natural birth, is more beneficial for both mother and child. To assess whether induction of labour starting in the evening, coinciding with the endogenous circadian rhythm, improves the outcome of labour compared with induction of labour starting in the early morning, organised to coincide with office hours. We contacted the Trials Search Co-ordinator to search the Cochrane Pregnancy and Childbirth Group's Trials Register (28 February 2012). In addition, we searched MEDLINE (1966 to 16 February 2012) and EMBASE (1980 to 16 February 2012). We included all published and unpublished randomised controlled trials. We excluded trials that employed quasi-random methods of treatment allocation. Two review authors independently assessed trials for inclusion and risk of bias. Two review authors independently extracted data. Data were checked for accuracy. Where necessary, we contacted study authors for additional information. The search resulted in 2693 articles that we screened on title and abstract for eligibility.Thirteen studies were selected for full text assessment. We included three randomised trials involving 1150 women. Two trials compared the administration of prostaglandins in the morning versus the evening in women with an unfavourable cervix, and one trial compared induction of labour in the morning versus the evening

  3. Ressenya a Sònia Gros, «Aquella dolçor amarga». La tradició amatòria clàssica en el Curial e Güelfa. València, Publicacions de la Universitat de València, 2015, 346 pp. ISBN: 978-84-370-9648-3

    Directory of Open Access Journals (Sweden)

    Adrià Martí i Badia

    2015-12-01

    Full Text Available Review to Sònia Gros, «Aquella dolçor amarga». La tradició amatòria clàssica en el Curial e Güelfa. València, Publicacions de laUniversitat de València, 2015, 346 pp, ISBN: 978-84-370-9648-3

  4. Juvenile first rib fracture caused by morning stretching.

    Science.gov (United States)

    Lee, Seung-Joon; Yie, Kilsoo; Chon, Sung Bin

    2012-08-01

    First rib fractures are very rare, being primarily associated with external blunt trauma. Related conditions, such as sudden contraction of the neck muscle, stress fractures, and fatigue fractures, have been reported sporadically. These fractures are mostly related to repetitive or explosive physical training. However, anatomical relationships and related injury mechanisms may cause first rib fractures without repetitive sports activity. To present a case of juvenile first rib fracture caused by morning stretching without sports activity. CASE  We present a rare case report of juvenile atraumatic first rib fracture. Physicians should be aware that even morning stretching with yawning can cause a first rib fracture in children. Awareness is important for early recognition, and proper management is critical for a pain-free return to normal life. An understanding of the mechanism of atraumatic first rib fracture is important. Copyright © 2012. Published by Elsevier Inc.

  5. Acupressure therapy for morning sickness. A controlled clinical trial.

    Science.gov (United States)

    Hyde, E

    1989-01-01

    A prospective, controlled clinical trial examined the efficacy of acupressure therapy for morning sickness, using a two group, random assignment, crossover design. Subjects in Group 1 (N = 8) used acupressure wristbands for five days, followed by five days without therapy. Subjects in Group 2 (N = 8) had no therapy for five days, followed by five days use of wristbands. The Multiple Affect Adjective Checklist and Sickness Impact Profile were used, and extent of nausea was assessed at baseline, day five, and day ten. Use of acupressure wristbands relieved morning sickness for 12 of 16 subjects (chi 2 = 5.31 with Yates' correction factor, df = 1, p less than .025). Acupressure therapy resulted in statistically significant (p less than .05) reductions in anxiety, depression, behavioral dysfunction, and nausea. Limitations of the study and suggestions for future research are presented.

  6. Morning akinesia in Parkinson's disease: challenges and solutions

    Directory of Open Access Journals (Sweden)

    Tambasco N

    2016-06-01

    Full Text Available Nicola Tambasco,1 Simone Simoni,1 Pasquale Nigro,1 Federico Paolini Paoletti,1 Erica Marsili,1 Paolo Calabresi1,2 1Neurology Clinic, Azienda Ospedaliera – Università di Perugia, Perugia, 2Neurophysiology Department, IRCCS Fondazione Santa Lucia, Rome, Italy Abstract: Motor complications of Parkinson's disease (PD have been reported to occur after a few years of treatment with levodopa (L-dopa. Morning akinesia is a delayed ON of the first L-dopa daily dose, occurring in almost 60% of patients on dopaminergic treatment. This is primarily a motor symptom, but has been recently recognized as being correlated with nonmotor fluctuations. Sleep disorders and gastrointestinal dysfunction might be the underlying mechanisms. Over the past 30 years, several pharmacological and nonpharmacological approaches have been investigated. Keywords: Parkinson's disease, morning akinesia, motor fluctuation, L-dopa 

  7. Pioneering Studies of the “Morning-After” Pill

    Science.gov (United States)

    Kunjappu, Mary J.

    2011-01-01

    Yale School of Medicine produced the first proof-of-concept study on the viability of a “morning-after” pill for human use. This study was a result of a fruitful collaboration between a pair of Yale scientists, Drs. John M. Morris and Gertrude van Wagenen, who sought a non-abortion, post-coital contraceptive. They tested a variety of hormones, hormone-based synthetic drugs, and other compounds in monkeys in an effort to uncover a compound that was non-toxic but highly effective. Unfortunately, although they were unable to identify such a drug, their initial studies inspired other scientists to further pursue the concept of a “morning-after” pill, leading to the development of Food and Drug Administration (FDA)-approved emergency contraceptives. PMID:21698041

  8. 3. Germain Gros.pmd

    African Journals Online (AJOL)

    daouda.thiam

    2009-12-02

    Dec 2, 2009 ... Chinese Economic Success and Policy. Lessons for .... Revolution – rather than the creation of new institutions. ..... Chinese economic policy is largely ... as Malaysia and Singapore, states 'intervene actively in the economy in.

  9. Morning Circadian Misalignment during Short Sleep Duration Impacts Insulin Sensitivity.

    Science.gov (United States)

    Eckel, Robert H; Depner, Christopher M; Perreault, Leigh; Markwald, Rachel R; Smith, Mark R; McHill, Andrew W; Higgins, Janine; Melanson, Edward L; Wright, Kenneth P

    2015-11-16

    Short sleep duration and circadian misalignment are hypothesized to causally contribute to health problems including obesity, diabetes, metabolic syndrome, heart disease, mood disorders, cognitive impairment, and accidents. Here, we investigated the influence of morning circadian misalignment induced by an imposed short nighttime sleep schedule on impaired insulin sensitivity, a precursor to diabetes. Imposed short sleep duration resulted in morning wakefulness occurring during the biological night (i.e., circadian misalignment)-a time when endogenous melatonin levels were still high indicating the internal circadian clock was still promoting sleep and related functions. We show the longer melatonin levels remained high after wake time, insulin sensitivity worsened. Overall, we find a simulated 5-day work week of 5-hr-per-night sleep opportunities and ad libitum food intake resulted in ∼20% reduced oral and intravenous insulin sensitivity in otherwise healthy men and women. Reduced insulin sensitivity was compensated by an increased insulin response to glucose, which may reflect an initial physiological adaptation to maintain normal blood sugar levels during sleep loss. Furthermore, we find that transitioning from the imposed short sleep schedule to 9-hr sleep opportunities for 3 days restored oral insulin sensitivity to baseline, but 5 days with 9-hr sleep opportunities was insufficient to restore intravenous insulin sensitivity to baseline. These findings indicate morning wakefulness and eating during the biological night is a novel mechanism by which short sleep duration contributes to metabolic dysregulation and suggests food intake during the biological night may contribute to other health problems associated with short sleep duration. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Misled by the Morning “Fasting” Plasma Glucose

    OpenAIRE

    King, Allen B

    2015-01-01

    Because of its ease and simplicity of its measurement, the morning fasting plasma glucose (FPG), has been as used a surrogate marker for the entire basal day when titrating once-nightly basal insulin. Common in obese insulin-treated patients with type 2 diabetes, late and large evening meals elevate the FPG. This has led to dosing of basal insulin well beyond the basal requirements and contributes to hypoglycemia and weight gain seen with this therapy. It is recommended that during basal insu...

  11. Pioneering Studies of the “Morning-After” Pill

    OpenAIRE

    Kunjappu, Mary J.

    2011-01-01

    Yale School of Medicine produced the first proof-of-concept study on the viability of a “morning-after” pill for human use. This study was a result of a fruitful collaboration between a pair of Yale scientists, Drs. John M. Morris and Gertrude van Wagenen, who sought a non-abortion, post-coital contraceptive. They tested a variety of hormones, hormone-based synthetic drugs, and other compounds in monkeys in an effort to uncover a compound that was non-toxic but highly effective. Unfortunately...

  12. New timetable for a Regular morning and evening shuttle

    CERN Multimedia

    TS Department

    2008-01-01

    Starting from 31 March 2008, for one month, a new timetable for a regular morning and evening shuttle serving LHC Points 2 and 5 will be put in place. You can find all the corresponding details on the FM group WEB page: http://ts-dep.web.cern.ch/ts-dep/groups/fm/logistique/shuttle_timetable.htm Please note that during April, all other requests for transport from Meyrin and Prévessin to the LHC Points via tel. 76969 during the day (between 8:30 and 17:30) will not be met. TS/FM group Tel. 160239

  13. New timetable for a morning and evening regular shuttle

    CERN Multimedia

    TS Department

    2008-01-01

    Starting from the 31st of March 2008 and for one month, a new timetable for a morning and evening regular shuttle serving LHC Points 2 and 5, will be put in place. You can find all the corresponding details in the FM group WEB page http://ts-dep.web.cern.ch/ts-dep/groups/fm/logistique/shuttle_timetable.htm Please note that during April, every other request of transfer from Meyrin and Prevessin towards LHC Points reaching the 76969 during the day (between 8:30 and 17:30) will not be satisfied. TS/FM group 160239

  14. MORN5 expression during craniofacial development and its interaction with the BMP and TGFB pathways

    Directory of Open Access Journals (Sweden)

    Petra Cela

    2016-08-01

    Full Text Available MORN5 (MORN repeat containing 5 is encoded by a locus positioned on chromosome 17 in the chicken genome. The MORN motif is found in multiple copies in several proteins including junctophilins or phosphatidylinositol phosphate kinase family and the MORN proteins themselves are found across the animal and plant kingdoms. MORN5 protein has a characteristic punctate pattern in the cytoplasm in immunofluorescence imaging. Previously, MORN5 was found among differentially expressed genes in a microarray profiling experiment of the chicken embryo head. Here, we provided in situ hybridization to analyse, in detail, the MORN5 expression in chick craniofacial structures. The expression of MORN5 was first observed at stage HH17-18 (E2.5. MORN5 expression gradually appeared on either side of the primitive oral cavity, within the maxillary region. At stage HH20 (E3, prominent expression was localised in the mandibular prominences lateral to the midline. From stage HH20 up to HH29 (E6, there was strong expression in restricted regions of the maxillary and mandibular prominences. The frontonasal mass (in the midline of the face expresses MORN5, starting at HH27 (E5. The expression was concentrated in the corners or globular processes, which will ultimately fuse with the cranial edges of the maxillary prominences. MORN5 expression was maintained in the fusion zone up to stage HH29. In sections in situs, MORN5 expression was localised preferentially in the mesenchyme. We examined signals that regulate MORN5 expression in the face based on a previous microarray study. Here we validated the array results with in situ hybridization and QPCR. MORN5 was downregulated 24h after Noggin and/or RA treatment. We also determined that BMP pathway genes are downstream of MORN5 following siRNA knockdown. Based on these results, we conclude that MORN5 is both regulated by and required for BMP signalling. The restricted expression of MORN5 in the lip fusion zone shown here

  15. Invertebrate and vertebrate class III myosins interact with MORN repeat-containing adaptor proteins.

    Directory of Open Access Journals (Sweden)

    Kirk L Mecklenburg

    Full Text Available In Drosophila photoreceptors, the NINAC-encoded myosin III is found in a complex with a small, MORN-repeat containing, protein Retinophilin (RTP. Expression of these two proteins in other cell types showed NINAC myosin III behavior is altered by RTP. NINAC deletion constructs were used to map the RTP binding site within the proximal tail domain of NINAC. In vertebrates, the RTP ortholog is MORN4. Co-precipitation experiments demonstrated that human MORN4 binds to human myosin IIIA (MYO3A. In COS7 cells, MORN4 and MYO3A, but not MORN4 and MYO3B, co-localize to actin rich filopodia extensions. Deletion analysis mapped the MORN4 binding to the proximal region of the MYO3A tail domain. MYO3A dependent MORN4 tip localization suggests that MYO3A functions as a motor that transports MORN4 to the filopodia tips and MORN4 may enhance MYO3A tip localization by tethering it to the plasma membrane at the protrusion tips. These results establish conserved features of the RTP/MORN4 family: they bind within the tail domain of myosin IIIs to control their behavior.

  16. Morning Glory Syndrome with Carotid and Middle Cerebral Artery Vasculopathy.

    Science.gov (United States)

    Nezzar, Hachemi; Mbekeani, Joyce N; Dalens, Helen

    2015-12-01

    To report a case of incidental asymptomatic atypical morning glory syndrome (MGS) with concomitant ipsilateral carotid and middle cerebral dysgenesis. A 6-year-old child was discovered to have incidental findings of MGS, with atypia. All visual functions were normal including vision and stereopsis. Neuroimaging revealed ipsilateral carotid and middle cerebral vascular narrowing without associated collateral vessels or cerebral ischemia commonly seen in Moyamoya disease. Subsequent annual examinations have been stable, without signs of progression. This case demonstrates disparity between structural aberrations and final visual and neurological function and reinforces the association between MGS and intracranial vascular disruption. Full ancillary ophthalmic and neuroimaging studies should be performed in all patients with MGS with interval reassessments, even when the patient is asymptomatic and functionally intact.

  17. Grey zone simulations of the morning convective boundary layer development

    Science.gov (United States)

    Efstathiou, G. A.; Beare, R. J.; Osborne, S.; Lock, A. P.

    2016-05-01

    Numerical simulations of two cases of morning boundary layer development are conducted to investigate the impact of grid resolution on mean profiles and turbulent kinetic energy (TKE) partitioning from the large eddy simulation (LES) to the mesoscale limit. Idealized LES, using the 3-D Smagorinsky scheme, is shown to be capable of reproducing the boundary layer evolution when compared against measurements. However, increasing grid spacing results in the damping of resolved TKE and the production of superadiabatic temperature profiles in the boundary layer. Turbulence initiation is significantly delayed, exhibiting an abrupt onset at intermediate resolutions. Two approaches, the bounding of vertical diffusion coefficient and the blending of the 3-D Smagorinsky with a nonlocal 1D scheme, are used to model subgrid diffusion at grey zone resolutions. Simulations are compared against the coarse-grained fields from the validated LES results for each case. Both methods exhibit particular strengths and weaknesses, indicating the compromise that needs to be made currently in high-resolution numerical weather prediction. The blending scheme is able to reproduce the adiabatic profiles although turbulence is underestimated in favor of the parametrized heat flux, and the spin-up of TKE remains delayed. In contrast, the bounding approach gives an evolution of TKE that follows the coarse-grained LES very well, relying on the resolved motions for the nonlocal heat flux. However, bounding gives unrealistic static instability in the early morning temperature profiles (similar to the 3-D Smagorinsky scheme) because model dynamics are unable to resolve TKE when the boundary layer is too shallow compared to the grid spacing.

  18. Features of an interactive writing discourse: conversational involvement, conventional knowledge, and internalization in "Morning Message".

    Science.gov (United States)

    Mariage, T V

    2001-01-01

    This study describes how meaning potentials were constructed in the literacy event known as Morning Message. Morning Message provided teachers and students with opportunities to construct a written text around the experiences of one student. This discourse of writing allowed for the examination of how meaning was orchestrated and scaffolded between the teacher and her students. Three findings are discussed, including the function of a series of conversational involvement moves utilized by the teacher, the specific writing conventions and metamessages afforded in the Morning Message dialogue, and an examination of how the social dialogues of Morning Message may have come to guide independent action as internalized processes on several transfer measures.

  19. An extremely high altitude plume seen at Mars morning terminator

    Science.gov (United States)

    Sanchez-Lavega, Agustin; Garcia-Muñoz, Antonio; Garcia-Melendo, Enrique; Perez-Hoyos, Santiago; Gomez-Forrellad, Josep M.; Pellier, Christophe; Delcroix, Marc; Lopez-Valverde, Miguel Angel; Gonzalez-Galindo, Francisco; Jaeschke, Wayne; Parker, Donald C.; Phillips, James H.; Peach, Damian

    2014-11-01

    We report the occurrence in March and April 2012 of two bright very high altitude plumes at the Martian terminator at 250 km or more above the surface, thus well into the ionosphere and bordering on the exosphere. They were located at about 195 deg West longitude and -45 deg latitude (at Terra Cimmeria) and lasted for about 10 days. The features showed day-to-day variability, and were seen at the morning terminator but not at the evening limb, which indicates rapid evolution in less than 10 hours and a cyclic behavior. Photometric measurements are used to explore two possible scenarios to explain their nature. If the phenomenon is due to suspended particles (dust, CO2 or H2O ice clouds) reflecting solar radiation, the mean size is about 0.1 microns with a nadir optical depth > 0.06. Alternatively, the plume could be auroral emission above a region with a strong magnetic anomaly and where aurora has previously been detected. Importantly, both explanations defy our current understanding of the Mars upper atmosphere.AcknowledgementsThis work was supported by the Spanish MINECO projects AYA2012-36666 with FEDER support, CONSOLIDER program ASTROMOL CSD2009-00038 and AYA2011-30613-CO2-1. Grupos Gobierno Vasco IT765-13 and UPV/EHU UFI11/55.

  20. Morning sickness: adaptive cause or nonadaptive consequence of embryo viability?

    Science.gov (United States)

    Flaxman, Samuel M; Sherman, Paul W

    2008-07-01

    "Morning sickness" is the common term for nausea and vomiting in early human pregnancy (NVP). Recent interest in why NVP occurs-that is, in the evolutionary costs and benefits of NVP-has spurred the development of two alternative hypotheses. The "prophylaxis," or "maternal and embryonic protection," hypothesis suggests that NVP serves a beneficial function by expelling foods that may contain harmful toxins and microorganisms and triggering aversions to such foods throughout pregnancy. The alternative "by-product" hypothesis suggests that NVP is a nonfunctional by-product of conflict--over resource allocation--between the pregnant woman and the embryo. The critical predictions of the prophylaxis hypothesis have been developed and tested, whereas the by-product hypothesis has not been subjected to similar scrutiny. To address this gap, we developed a graphical model and used it to derive predictions from the by-product hypothesis under two different assumptions, namely, that NVP is either (i) a by-product of current conflict between a pregnant woman and an embryo or (ii) a by-product of honest signals of viability produced by the embryo. Neither version of the by-product hypothesis is fully consistent with available data. By contrast, the timing of NVP, its variation among societies, and associated patterns of food cravings and aversions are consistent with the prophylaxis hypothesis.

  1. Effects of load on good morning kinematics and EMG activity.

    Science.gov (United States)

    Vigotsky, Andrew David; Harper, Erin Nicole; Ryan, David Russell; Contreras, Bret

    2015-01-01

    Many strength and conditioning coaches utilize the good morning (GM) to strengthen the hamstrings and spinal erectors. However, little research exists on its electromyography (EMG) activity and kinematics, and how these variables change as a function of load. The purpose of this investigation was to examine how estimated hamstring length, integrated EMG (IEMG) activity of the hamstrings and spinal erectors, and kinematics of the lumbar spine, hip, knee, and ankle are affected by changes in load. Fifteen trained male participants (age = 24.6 ± 5.3 years; body mass = 84.7 ± 11.3 kg; height = 180.9 ± 6.8 cm) were recruited for this study. Participants performed five sets of the GM, utilizing 50, 60, 70, 80, and 90% of one-repetition maximum (1RM) in a randomized fashion. IEMG activity of hamstrings and spinal erectors tended to increase with load. Knee flexion increased with load on all trials. Estimated hamstring length decreased with load. However, lumbar flexion, hip flexion, and plantar flexion experienced no remarkable changes between trials. These data provide insight as to how changing the load of the GM affects EMG activity, kinematic variables, and estimated hamstring length. Implications for hamstring injury prevention are discussed. More research is needed for further insight as to how load affects EMG activity and kinematics of other exercises.

  2. Effects of load on good morning kinematics and EMG activity

    Directory of Open Access Journals (Sweden)

    Andrew David Vigotsky

    2015-01-01

    Full Text Available Many strength and conditioning coaches utilize the good morning (GM to strengthen the hamstrings and spinal erectors. However, little research exists on its electromyography (EMG activity and kinematics, and how these variables change as a function of load. The purpose of this investigation was to examine how estimated hamstring length, integrated EMG (IEMG activity of the hamstrings and spinal erectors, and kinematics of the lumbar spine, hip, knee, and ankle are affected by changes in load. Fifteen trained male participants (age = 24.6 ± 5.3 years; body mass = 84.7 ± 11.3 kg; height = 180.9 ± 6.8 cm were recruited for this study. Participants performed five sets of the GM, utilizing 50, 60, 70, 80, and 90% of one-repetition maximum (1RM in a randomized fashion. IEMG activity of hamstrings and spinal erectors tended to increase with load. Knee flexion increased with load on all trials. Estimated hamstring length decreased with load. However, lumbar flexion, hip flexion, and plantar flexion experienced no remarkable changes between trials. These data provide insight as to how changing the load of the GM affects EMG activity, kinematic variables, and estimated hamstring length. Implications for hamstring injury prevention are discussed. More research is needed for further insight as to how load affects EMG activity and kinematics of other exercises.

  3. Morning/Evening Differences in Somatosensory Inputs for Postural Control

    Directory of Open Access Journals (Sweden)

    Clément Bougard

    2014-01-01

    Full Text Available The underlying processes responsible for the differences between morning and afternoon measurements of postural control have not yet been clearly identified. This study was conducted to specify the role played by vestibular, visual, and somatosensory inputs in postural balance and their link with the diurnal fluctuations of body temperature and vigilance level. Nineteen healthy male subjects (mean age: 20.5 ± 1.3 years participated in test sessions at 6:00 a.m. and 6:00 p.m. after a normal night’s sleep. Temperature was measured before the subjects completed a sign cancellation test and a postural control evaluation with eyes both open and closed. Our results confirmed that postural control improved throughout the day according to the circadian rhythm of body temperature and sleepiness/vigilance. The path length as a function of surface ratio increased between 6:00 a.m. and 6:00 p.m. This is due to a decrease in the centre-of-pressure surface area, which is associated with an increase in path length. Romberg’s index did not change throughout the day; however, the spectral analysis (fast Fourier transform of the centre-of-pressure excursions (in anteroposterior and mediolateral directions indicated that diurnal fluctuations in postural control may occur via changes in the different processes responsible for readjustment via muscle contractions.

  4. Hello Sunday Morning: Alcohol, (non)consumption and selfhood.

    Science.gov (United States)

    Pennay, Amy; MacLean, Sarah; Rankin, Georgia

    2016-02-01

    Hello Sunday Morning (HSM) is an online program that encourages people to commit to a period of non-drinking and blog about their experiences. The purpose of this paper is to explore how HSM members negotiated their periods of abstention, with a focus on how not drinking influenced their narratives of selfhood. Thematic analysis was undertaken of 2844 blog posts from 154 Victorians who signed up to HSM in 2013 or 2014. Analysis revealed three key narratives of selfhood offered by participants: (1) abstinence resulting in a disrupted sense of self, (2) non-consumption facilitating the development of a new healthy self, and (3) anti-consumption facilitating the development of a resistant self. Individuals construct and maintain their sense of self through consumption (or non-consumption) activities, and this occurs within the broader context of the relationship between selfhood, consumption and culture. HSM members developed narratives of self by drawing on a range of wider discursive structures concerning pleasure, healthism and resistance. The typologies of non-drinking selves identified in this paper could be disseminated through platforms such as HSM to support people who are new to non-drinking in choosing how they might construct and enact alternative selfhoods in contexts where alcohol consumption is deeply embedded. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Lam Kin Chung Morning Sun China- Japan Friendship Fund Set up

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    <正>Lam Kin Chung Morning Sun Charity Fund of HoneKong has decided to donate, from January 2004, 100,000 RMB yuan each year for 5 consecutive years, which totals 500,000 RMB yuan, to set up the Lam Kin Chung Morning Sun China-Japan Friendship Fund under the China Friend-

  6. Solar flux variation of the electron temperature morning overshoot in the equatorial F region

    DEFF Research Database (Denmark)

    Stolle, Claudia; Liu, H.; Truhlik, V.

    2011-01-01

    Using 8 years of CHAMP satellite observations of the equatorial electron temperature, T-e, we investigate its behavior during the morning overshoot and at ionospheric altitudes below 450 km including its variation with solar activity. The morning T-e has a maximum at the dip equator and decreases...

  7. Morning anaerobic performance is not altered by vigilance impairment.

    Directory of Open Access Journals (Sweden)

    Romain Lericollais

    Full Text Available The aim of this study was to determine the role played by vigilance on the anaerobic performance recorded during a Wingate test performed at the bathyphase (nadir of the circadian rhythmicity. Twenty active male participants performed a 60-s Wingate test at 6 a.m. during 3 test sessions in counter-balanced order the day after either (i a normal reference night, (ii a total sleep deprivation night, or (iii a total sleep deprivation night associated with an extended simulated driving task from 9 p.m. to 5 a.m. During this task, the number of inappropriate line crossings (ILCs was used to control and quantify the effective decrease in the level of vigilance. The main findings show that (i vigilance of each participant was significantly altered (i.e., a drastic and progressive increase in ILCs is shown during the 7.5 hours of driving by the sleep deprivation night associated with an extended driving task; (ii the subjective evaluation of vigilance performed by self-rated scale revealed an increased impairment of the vigilance level between the normal reference night, the total sleep deprivation night and the total sleep deprivation night associated with an extended driving task; and (iii the morning following this last condition, during the Wingate test, the recorded cycling biomechanical parameters (peak power, mean power and fatigue index values, power decrease, and cycling kinetic and kinematic patterns were not significantly different from the two other conditions. Consequently, these results show that anaerobic performances recorded during a Wingate test performed at the bathyphase of the circadian rhythmicity are not altered by a drastic impairment in vigilance. These findings seem to indicate that vigilance is probably not a factor that contributes to circadian variations in anaerobic performance.

  8. Morning blood pressure surge: the reliability of different definitions.

    Science.gov (United States)

    Stergiou, George S; Mastorantonakis, Stylianos E; Roussias, Leonidas G

    2008-08-01

    Preliminary evidence suggests that the morning surge (MS) in blood pressure (BP) is an independent predictor of cerebrovascular disease. However, the optimal definition of MS is uncertain. To compare the reproducibility of several MS definitions used in the literature, 132 untreated hypertensives were assessed with ambulatory BP monitoring twice, 2 weeks apart. Five MS definitions were compared. MS-1: the average BP of the first hour after rising minus the average BP of the first hour before rising; MS-2: BP 2 h after rising minus that of 2 h before rising; MS-3: BP 3 h after rising minus that of 3 h before rising; MS-4: BP 2 h after rising minus the average BP during sleep; MS-5: BP 2 h after rising minus the average BP of 3 consecutive readings, centered on the lowest reading during sleep. The reproducibility of each MS definition was assessed using the concordance correlation coefficient (CCC), the standard deviation of differences (SDD) and the coefficient of variation (CV) between repeated MS assessments, and the agreement in detecting "surgers," defined as subjects at the top quartile (Q4) of the MS distribution. CCCs were 0.20/0.30, 0.43/0.45, 0.53/0.51, 0.51/0.47, and 0.46/0.48 (systolic/diastolic) for MS-1 to MS-5 respectively; SDDs were 14.3/11.4, 12.1/9.9, 11.2/9.5, 10.3/8.2, and 11.9/9.8, respectively; CVs were 0.49/0.57, 0.44/0.39, 0.37/0.35, 0.36/0.31, and 0.27/0.24, respectively; and the agreement in detecting "surgers" was 69%/70%, 71%/76%, 75%/75%, 81%/83%, and 74%/75%, with kappa of 0.18/0.20, 0.23/0.36, 0.33/0.33, 0.49/0.53 and 0.29/0.31, respectively. There are important differences in the reproducibility of MS calculated by different methods. MS4 appears to provide the most reproducible definition of MS.

  9. Once-daily atomoxetine for treating pediatric attention-deficit/hyperactivity disorder: comparison of morning and evening dosing.

    Science.gov (United States)

    Block, Stan L; Kelsey, Douglas; Coury, Daniel; Lewis, Donald; Quintana, Humberto; Sutton, Virginia; Schuh, Kory; Allen, Albert J; Sumner, Calvin

    2009-09-01

    In this 3-arm, randomized, double-blind trial, once-daily morning-dosed atomoxetine, evening-dosed atomoxetine, and placebo were compared for treating pediatric attention-deficit/hyperactivity disorder (ADHD). Patients received morning atomoxetine/evening placebo (n = 102), morning placebo/evening atomoxetine (n = 93), or morning placebo/evening placebo (n = 93) for about 6 weeks. Core symptom efficacy was measured at weeks 0, 1, 3, and 6. Parent assessments of the child's home behaviors in the evening and early morning were collected daily during the first 2 weeks of treatment. Morning-dosed and evening-dosed atomoxetine significantly decreased core ADHD symptoms relative to placebo and produced symptom improvements that were measured up to 24 hours later. Morning dosing was superior to evening dosing on some efficacy measures. Evening dosing showed greater tolerability with significantly more patients receiving morning atomoxetine reporting at least 1 adverse event than those receiving evening atomoxetine.

  10. Changes in the processing of heavy {alpha}-contaminated equipment at the Marcoule center; L'evolution du conditionnement des gros materiels contamines en {alpha} sur le centre de Marcoule

    Energy Technology Data Exchange (ETDEWEB)

    Seyfried, P. [Commissariat a l' Energie Atomique, Chusclan (France). Centre de Production de Plutonium de Marcoule

    1969-07-01

    The processing of heavy {alpha}-contaminated equipment at the Marcoule Centre has been carried out for a long time by a rather expensive 'manual' method. It has become necessary to reduce these costs by using more automated methods. Two studies which have been carried out have shown that when the amount of waste to be treated is large and is composed mainly of plastic material, it is possible to design economic installations using cooling and shock demolition, conventional compaction leading to rather poor results. For average quantities, a cutting-up reservoir, used also for other purposes, makes it possible to solve these processing problems at Marcoule. The costs involved are much lower than those previously required in the case of so-called 'manual' methods. (author) [French] Le conditionnement du gros materiel contamine en {alpha} a longtemps ete effectue sur le Centre de Marcoule par une methode 'manuelle' assez couteuse. Il est apparu necessaire de chercher a reduire les couts en utilisant des methodes plus automatisees. Deux etudes ont permis de montrer que lorsque les quantites a traiter sont grandes et interessent surtout des dechets plastiques, on pouvait concevoir economiquement des installations utilisant le refroidissement et choc, le compactage classique donnant des resultats assez decevants. Pour les quantites moyennes, une piscine de decoupage, utilisable d'ailleurs a d'autres fins, permet de resoudre, a Marcoule, le probleme du conditionnement. Les frais sont tres inferieurs a ceux anciennement engages avec les methodes 'manuelles'. (auteur)

  11. Differential islet and incretin hormone responses in morning versus afternoon after standardized meal in healthy men

    DEFF Research Database (Denmark)

    Lindgren, Ola; Mari, Andrea; Deacon, Carolyn F

    2009-01-01

    ) and total (t) glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) after meal ingestion and made an estimation of beta-cell function by model analysis of glucose and C-peptide. RESULTS: Peak glucose was lower in the morning than in the afternoon (6.1 +/- 0.2 vs. 7.4 +/- 0....../liter . min, P = 0.007) were all higher in the morning. AUC30(iGLP-1) (r = 0.68; P = 0.021) and AUC30(iGIP) (r = 0.78; P = 0.001) both correlated to AUC30(insulin). Model analysis of beta-cell function showed a higher first-hour potentiation factor in the morning (P = 0.009). This correlated negatively...... with the 60-min glucose level (r = -0.63; P cell function, and lower glucose after the morning...

  12. Comparison of overnight, morning and 24-hour urine collections in the assessment of diabetic microalbuminuria

    DEFF Research Database (Denmark)

    Eshøj, O; Feldt-Rasmussen, B; Larsen, M L

    1987-01-01

    With the aim of comparing different urine collection periods in the assessment of micro-albuminuria, urinary albumin excretion rates (AERs) were measured in samples from 24 h, overnight, and morning urine collections in 54 patients aged 17 to 62 years with insulin-dependent diabetes mellitus...... with a mean duration of 15 years. The AER in overnight urine was found to be reduced by 25% compared to the rate in 24 h and morning urine. Assessing the ability to predict a 24 h AER within the microalbuminuric range (20-200 micrograms/min) we found a sensitivity of 90% and a specificity of 88% for both...... overnight and morning urine samples. These values were slightly improved by relating AER to the excretion of creatinine and it is concluded that overnight as well as morning urine collections can be used when diagnosing microalbuminuria in insulin-dependent diabetics. Furthermore the results show...

  13. Breathe Fresh Morning:China-Columbia Business Breakfast Meeting

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ On February 16, the China Council for the Promotion of International Trade (CCPIT) and the National Business Association of Columbia (ANDI) jointly hosted the China-Columbia Business Breakfast Meeting in Bogota, capital city of Columbia. Chinese Vice Presi-dent Xi Jinping who was on an official visit to Columbia and Columbian Vice President Francisco Santos attended the event.

  14. Predictors and Trajectories of Morning Fatigue Are Distinct from Evening Fatigue

    Science.gov (United States)

    Wright, Fay; Melkus, Gail D’Eramo; Hammer, Marilyn; Schmidt, Brian L.; Knobf, M. Tish; Paul, Steven M.; Cartwright, Frances; Mastick, Judy; Cooper, Bruce A.; Chen, Lee-May; Melisko, Michelle; Levine, Jon D.; Kober, Kord; Aouizerat, Bradley E.; Miaskowski, Christine

    2015-01-01

    Context Fatigue is the most common symptom in oncology patients during chemotherapy (CTX). Little is known about the predictors of interindividual variability in initial levels and trajectories of morning fatigue severity in these patients. Objectives An evaluation was done to determine which demographic, clinical, and symptom characteristics were associated with initial levels as well as the trajectories of morning fatigue and to compare findings with our companion paper on evening fatigue. Methods A sample of outpatients with breast, gastrointestinal, gynecological, and lung cancer (N=586) completed demographic and symptom questionnaires a total of six times over two cycles of CTX. Fatigue severity was evaluated using the Lee Fatigue Scale. Hierarchical linear modeling (HLM) was used to answer the study objectives. Results A large amount of interindividual variability was found in the morning fatigue trajectories. A piecewise model fit the data best. Patients with higher body mass index (BMI), who did not exercise regularly, with a lower functional status, and who had higher levels of state anxiety, sleep disturbance and depressive symptoms, reported higher levels of morning fatigue at enrollment. Variations in the trajectories of morning fatigue were predicted by the patients’ ethnicity and younger age. Conclusion The modifiable risk factors that were associated with only morning fatigue were BMI, exercise, and state anxiety. Modifiable risk factors that were associated with both morning and evening fatigue included functional status, depressive symptoms, and sleep disturbance. Using this information, clinicians can identify patients at higher risk for more severe morning fatigue and evening fatigue, provide individualized patient education, and tailor interventions to address the modifiable risk factors. PMID:25828559

  15. How to deal with morning bad breath: A randomized, crossover clinical trial

    OpenAIRE

    Jeronimo M Oliveira-Neto; Sandra Sato; Vinicius Pedrazzi

    2013-01-01

    Context: The absence of a protocol for the treatment of halitosis has led us to compare mouthrinses with mechanical oral hygiene procedures for treating morning breath by employing a hand-held sulfide monitor. Aims: To compare the efficacy of five modalities of treatment for controlling morning halitosis in subjects with no dental or periodontal disease. Settings and Design: This is a five-period, randomized, crossover clinical trial. Materials and Methods: Twenty volunteers were randomly ass...

  16. Basal encephalocele associated with morning glory syndrome: case report Encefalocele basal associada a síndrome "morning glory": relato de caso

    Directory of Open Access Journals (Sweden)

    Ivanete Minotto

    2007-12-01

    Full Text Available The basal encephaloceles refer to rare entities and they correspond to herniation of brain tissue through defects of skull along the cribiform plate or the sphenoid bone. A rare morning glory syndrome, with characteristic retinal defect has been reported in association with basal encephaloceles. Hypophysis hormonal deficiencies may occur. We accounted for a pituitary dwarfism with delayed diagnosed transsphenoidal encephalocele associated with morning glory syndrome, showing the alterations found in retinography, computed tomography and magnetic resonance imaging.As encefaloceles basais são entidades raras e correspondem a herniações do tecido cerebral através de um defeito do crânio, ao longo da lâmina crivosa etmoidal ou do osso esfenoidal. A rara síndrome morning glory, com alterações de fundo de olho características pode apresentar-se associada à encefalocele basal. Deficiências hormonais hipofisárias podem ocorrer. Relatamos caso de nanismo hipofisário com encefalocele transesfenoidal de diagnóstico tardio associada à síndrome de morning glory, mostrando as alterações na retinografia, tomografia computadorizada e ressonância magnética.

  17. Nation

    DEFF Research Database (Denmark)

    Østergaard, Uffe

    2014-01-01

    Nation er et gammelt begreb, som kommer af det latinske ord for fødsel, natio. Nationalisme bygger på forestillingen om, at mennesker har én og kun én national identitet og har ret til deres egen nationalstat. Ordet og forestillingen er kun godt 200 år gammel, og i 1900-tallet har ideologien bredt...... sig over hele verden. Nationalisme er blevet global....

  18. Phylogenetics and diversification of morning glories (tribe Ipomoeeae, Convolvulaceae) based on whole plastome sequences.

    Science.gov (United States)

    Eserman, Lauren A; Tiley, George P; Jarret, Robert L; Leebens-Mack, Jim H; Miller, Richard E

    2014-01-01

    Morning glories are an emerging model system, and resolving phylogenetic relationships is critical for understanding their evolution. Phylogenetic studies demonstrated that the largest morning glory genus, Ipomoea, is not monophyletic, and nine other genera are derived from within Ipomoea. Therefore, systematic research is focused on the monophyletic tribe Ipomoeeae (ca. 650-900 species). We used whole plastomes to infer relationships across Ipomoeeae. Whole plastomes were sequenced for 29 morning glory species, representing major lineages. Phylogenies were estimated using alignments of 82 plastid genes and whole plastomes. Divergence times were estimated using three fossil calibration points. Finally, evolution of root architecture, flower color, and ergot alkaloid presence was examined. Phylogenies estimated from both data sets had nearly identical topologies. Phylogenetic results are generally consistent with prior phylogenetic hypotheses. Higher-level relationships with weak support in previous studies were recovered here with strong support. Molecular dating analysis suggests a late Eocene divergence time for the Ipomoeeae. The two clades within the tribe, Argyreiinae and Astripomoeinae, diversified at similar times. Reconstructed most recent common ancestor of the Ipomoeeae had blue flowers, an association with ergot-producing fungi, and either tuberous or fibrous roots. Phylogenetic results provide confidence in relationships among Ipomoeeae lineages. Divergence time estimation results provide a temporal context for diversification of morning glories. Ancestral character reconstructions support previous findings that morning glory morphology is evolutionarily labile. Taken together, our study provides strong resolution of the morning glory phylogeny, which is broadly applicable to the evolution and ecology of these fascinating species.

  19. Gaming the System: Creation of a Random Case-Generating Game for Use in Morning Report.

    Science.gov (United States)

    Kamra, Pallavi; Borman-Shoap, Emily C; Zhang, Lei; Pitt, Michael B

    2017-09-16

    Case-based morning reports are a staple of residency education. Little is known about the role of game-based learning in facilitating case-based discussions. Compare an educational game that can be used for creating impromptu case-based sessions to traditional morning report. We created a game called Differential Diagnosis Slot Machine, which allows participants to quickly generate theoretical cases for discussion.Five traditional morning report (TMR) and game-based morning report (GBMR) sessions were conducted. Participants completed an anonymous survey after each session rating their learning, enjoyment, participation, and desire for similar future sessions. Learners also described who they learned from during the session. Two-group comparison was done using logistic regression with generalized estimating equations. Statistical significance was determined at p game-based morning report was rated as equivalent or better than traditional morning report in all self-rated categories. It also allowed for more peer-directed learning and as it encourages creative problem solving may be a useful adjunct for case-based teaching. Copyright © 2017 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

  20. Losartan/Hydrochlorothiazide Combination Therapy Surpasses High-dose Angiotensin Receptor Blocker in the Reduction of Morning Home Blood Pressure in Patients with Morning Hypertension

    Directory of Open Access Journals (Sweden)

    Nakamura,Yoshio

    2012-12-01

    Full Text Available Angiotensin receptor blockers (ARBs are the first-line antihypertensive agents. In clinical practice, it is often difficult to achieve the recommended blood pressure level by ARBs in their ordinal dosages alone. This study examined the practical efficacy of a combination therapy of ARB with thiazide diuretics for lowering morning home blood pressure (MHBP in comparison to high-dose ARB therapy in patients with morning hypertension administered an ordinal dosage of ARB. This study was performed in a prospective, randomized, open-labeled and blind-endpoint fashion. Patients were considered to have morning hypertension when their self-measured systolic MHBPs were 135mmHg or higher, irrespective of their diastolic MHBP and office blood pressures (OBPs. Forty-eight outpatients with morning hypertension receiving the ordinal dosage of ARB were given either losartan/hydrochlorothiazide (n=26 or high-dose ARB (n=22 in place of their previously prescribed ARB. No change in any medication was permitted during this period. Decreases of both systolic and diastolic MHBP after 3 months of treatment were significantly greater in the losartan/hydrochlorothiazide group than in the high-dose ARB group (p<0.05, respectively. The ratio of adverse events was somewhat high (23.1% in the losartan/hydrochlorothiazide group, 9.1% in the high-dose ARB group, respectively. However, there were no significant differences in any particular adverse event between groups. This study suggested losartan/hydrochlorothiazide might be superior to high-dose ARB for reducing morning home blood pressure.

  1. Association between the rate of the morning surge in blood pressure and cardiovascular events and stroke

    Institute of Scientific and Technical Information of China (English)

    LUO Yu; WANG Yan-li; WU Ying-biao; XU Yao; Geoffrey A.Head; Macgrathy Barry; LIANG Yu-lu

    2013-01-01

    Background The exaggerated surge in morning blood pressure (BP) that many patients experience upon awakening may be closely related to target organ damage and may be a predictor of cardiovascular complications.However,no previous studies have evaluated the rate of this surge independently of the evening period.It remains unclear whether the rate of increase experienced during the surge is a significant or independent determinant of cardiovascular events.Methods We randomly selected 340 ambulatory BP monitoring (ABPM) patients.All subjects without type 2 diabetes mellitus were divided into two groups:hypertensive group (n=170) and normotensive group (n=170).We analyzed ambulatory blood pressure recordings using a double logistic curve-fitting procedure to determine whether the magnitude of the surge in BP and heart rate (HR) in the morning is related to the level of BP in hypertensive individuals.We evaluated the association between the rate of the morning surge in systolic BP (SBP) and the incidence of myocardial infarction and stroke in normotensive and hypertensive subjects.Results Comparisons between hypertensive and normotensive subjects showed that the rates of the morning surges in SBP,mean BP (MBP),and diastolic BP (DBP) were greater in the hypertensive group (P <0.05) than in the normotensive group.The rate of morning surge in BP was found to be correlated with the daytime SBP (r=0.236,P <0.01),the difference between the day and night plateau (r=0.249,P <0.01),and the night SBP (r=-0.160,P <0.05),respectively.After controlling for age,sex,and mean systolic pressure within 24 hours (24 h SBP),the rate of morning surge in SBP was closely correlated with daytime SBP (r=0.463,P <0.001),night SBP (r=-0.173,P <0.05),and the difference between the day and night plateau (r=0.267,P <0.001).Logistic regression analysis revealed that the rate of morning surge in SBP was an independent determinant of myocardial infarction (OR=1.266,95% CI=1.153-1.389,P

  2. EPA Holds National Sustainable Design Expo

    Science.gov (United States)

    WASHINGTON, DC - Environmental Protection Agency (EPA) Deputy Administrator Stan Meiburg will open the 11th Annual National Sustainable Design Expo Saturday morning in Alexandria, Va. The expo will host student teams from colleges and universities across t

  3. Morning and evening physical exercise differentially regulate the autonomic nervous system during nocturnal sleep in humans.

    Science.gov (United States)

    Yamanaka, Yujiro; Hashimoto, Satoko; Takasu, Nana N; Tanahashi, Yusuke; Nishide, Shin-Ya; Honma, Sato; Honma, Ken-Ichi

    2015-11-01

    Effects of daily physical exercise in the morning or in the evening were examined on circadian rhythms in plasma melatonin and core body temperature of healthy young males who stayed in an experimental facility for 7 days under dim light conditions (Sleep polysomnogram (PSG) and heart rate variability (HRV) were also measured. Subjects performed 2-h intermittent physical exercise with a bicycle ergometer at ZT3 or at ZT10 for four consecutive days, where zeitgeber time 0 (ZT0) was the time of wake-up. The rising phase of plasma melatonin rhythm was delayed by 1.1 h without exercise. Phase-delay shifts of a similar extent were detected by morning and evening exercise. But the falling phase shifted only after evening exercise by 1.0 h. The sleep PSG did not change after morning exercise, while Stage 1+2 sleep significantly decreased by 13.0% without exercise, and RE sleep decreased by 10.5% after evening exercise. The nocturnal decline of rectal temperature was attenuated by evening exercise, but not by morning exercise. HRV during sleep changed differentially. Very low frequency (VLF) waves increased without exercise. VLF, low frequency (LF), and high frequency (HF) waves increased after morning exercise, whereas HR increased after evening exercise. Morning exercise eventually enhanced the parasympathetic activity, as indicated by HRV, while evening exercise activated the sympathetic activity, as indicated by increase in heart rate in the following nocturnal sleep. These findings indicated differential effects of morning and evening exercise on the circadian melatonin rhythm, PSG, and HRV.

  4. Elevated nocturnal and morning blood pressure in patients with obstructive sleep apnea syndrome

    Institute of Scientific and Technical Information of China (English)

    HE Quan-ying; WANG Bei; LIN Qi-chang; ZHANG Jin-nong; LIU Hui-guo; LUO Yuan-ming; LIU Jian-hong; WANG Shi; XIAO Gao-hui; LU Gan; ZHANG Jin; FENG Jing; FENG Xue-wei; CHEN Bao-yuan; ZHANG Xi-long; LIANG Zong-an; HUANG Shao-guang; KANG Jian; WANG Guang-fa; ZHANG Li-qiang; MA Li-jun

    2012-01-01

    Background The nocturnal nondipping and elevated morning blood pressure (BP) in patients with obstructive sleep apnea syndrome (OSAS) have not yet been well investigated in Chinese patients.This study aimed to describe the BP profile,and to elucidate the relationships between daytime BP and nighttime BP,and between evening BP and morning BP in patients with OSAS.Methods Twenty teaching hospital sleep centers in China were organized by the Chinese Medical Association to participate in this study and 2297 patients were recruited between January 2004 and April 2006.BP assessments were made at four time points (daytime,evening,nighttime and morning) and polysomnography (PSG) was performed and subjects were classified into four groups by their apnea-hypopnea index (AHI):control,n=213 with AHI<5; mild,n=420 with AHI ≥5 and<15; moderate,n=460 with AHI≥15 and<30; and severe,n=1204 with AHI >30.SPSS 11.5 software package was used for statistical analysis and figure drawing.Results All the average daytime,nighttime,evening and morning BPs were positively correlated with AHI and negatively correlated with nadir nocturnal oxygen saturation.The ralios of nighttime/daytime and morning/evening average BP were positively correlated with AHI.The ratio of nighttime/daytime systolic BP became a “reversed BP dipping” pattern until the classification reached severe,while the ratio of nighttime/daytime diastolic BP became reversed at moderate.Similarly,the ratio of morning/evening diastolic BP becomes reversed even at mild.Conclusions OSAS may result in higher BP levels at all four time points.The ratios of nighttime/daytime and morning/evening BP increase with increased AHI.The increasing of diastolic BP,which is inclined to rise more quickly,is not parallel with increasing systolic BP.

  5. Morning glory systemically accumulates scopoletin and scopolin after interaction with Fusarium oxysporum.

    Science.gov (United States)

    Shimizu, Bun-ichi; Miyagawa, Hisashi; Ueno, Tamio; Sakata, Kanzo; Watanabe, Ken; Ogawa, Kei

    2005-01-01

    An isolate of non-pathogenic Fusarium, Fusarium oxysporum 101-2 (NPF), induces resistance in the cuttings of morning glory against Fusarium wilt caused by F. oxysporum f. sp. batatas O-17 (PF). The effect of NPF on phenylpropanoid metabolism in morning glory cuttings was studied. It was found that morning glory tissues responded to treatment with NPF bud-cell suspension (108 bud-cells/ml) with the activation of phenylalanine ammonia-lyase (PAL). PAL activity was induced faster and greater in the NPF-treated cuttings compared to cuttings of a distilled water control. High performance liquid chromatography analysis of the extract from tissues of morning glory cuttings after NPF treatment showed a quicker induction of scopoletin and scopolin synthesis than that seen in the control cuttings. PF also the induced synthesis of these compounds at 10(5) bud-cells/ml, but inhibited it at 10(8) bud-cells/ml. Possibly PF produced constituent(s) that elicited the inhibitory effect on induction of the resistance reaction. These compounds could potentially be useful as markers to detect early beginning interactions between Fusarium and morning glory tissues cuttings.

  6. Morning report blog: a web-based tool to enhance case-based learning.

    Science.gov (United States)

    Bogoch, Isaac I; Frost, David W; Bridge, Suzanne; Lee, Todd C; Gold, Wayne L; Panisko, Daniel M; Cavalcanti, Rodrigo B

    2012-01-01

    Morning report is an interactive case-based teaching session common to internal medicine training programs across North America. We report here on a morning report web log ("blog"), created and updated after morning report sessions by the Chief Medical Resident with pertinent clinical topics, links to journal articles, and medical images. Trainees on their internal medicine rotation were e-mailed a web link with each posting. The aim was to enhance learning on clinical topics discussed at morning report by reinforcing topics and promoting further reading. The educational impact of the blog was evaluated using detailed web metrics and surveys of attendees. The intended audience spent on average more than 5 min reading the blog and viewed more than 3 pages per visit. Almost half of attendees accessed the blog after completing their internal medicine rotation. The blog was also accessed by a global audience. Trainees rated the blogs a useful learning tool and cited it to be among the top 3 educational resources accessed during their rotation. In summary, a morning report blog was perceived by learners to be an effective complement to case-based teaching sessions. The combination of novel web metrics and survey data allowed for a multifaceted evaluation of the educational impact of the blog.

  7. Standing body sway in women with and without morning sickness in pregnancy.

    Science.gov (United States)

    Yu, Yawen; Chung, Hyun Chae; Hemingway, Lauren; Stoffregen, Thomas A

    2013-01-01

    Morning sickness typically is attributed to hormonal changes in pregnancy. We asked whether morning sickness is associated with changes in standing postural equilibrium, as occurs in research on visually induced motion sickness. Twenty-one pregnant women (mean age=30 years, mean height=163cm; mean weight=63kg) were tested during the first trimester. Laboratory-based balance measures were collected, along with perceived postural stability, the presence of morning sickness, and the severity of subjective symptoms. We varied the distance between the feet and the visual task performed during stance. Participants were classified as either experiencing (Sick, n=12) or not experiencing (Well, n=9) morning sickness. Perceived balance stability was lower for Sick than for Well women. The positional variability of sway was reduced for the Sick group, relative to the Well group. Positional variability decreased with wider stance width, and was reduced during performance of a more demanding visual task. Stance width and visual task also influenced the temporal dynamics of sway. Effects of stance width and visual task on postural sway were similar to effects in non-pregnant adults, suggesting that sensitive tuning of posture is maintained during the first trimester. The findings suggest that women with morning sickness may attempt to stabilize their bodies by reducing overall body sway. It may be useful to recommend that women adopt wider stance early in pregnancy.

  8. A Toxoplasma MORN1 null mutant undergoes repeated divisions but is defective in basal assembly, apicoplast division and cytokinesis.

    Directory of Open Access Journals (Sweden)

    Alexander Lorestani

    Full Text Available The membrane occupation and recognition nexus protein 1 (MORN1 is highly conserved among apicomplexan parasites and is associated with several structures that have a role in cell division. Here we dissected the role of MORN1 using the relatively simple budding process of Toxoplasma gondii as a model. Ablation of MORN1 in a conditional null mutant resulted in pronounced defects suggesting a central role for MORN1 in apicoplast segregation and in daughter cell budding. Lack of MORN1 resulted in double-headed parasites. These Janus-headed parasites form two complete apical complexes but fail to assemble a basal complex. Moreover, these parasites were capable of undergoing several more budding rounds resulting in the formation of up to 16-headed parasites conjoined at the basal end. Despite this segregation defect, the mother's cytoskeleton was completely disassembled in every budding round. Overall this argues that successful completion of the budding is not required for cell cycle progression. None of the known basal complex components, including a set of recently identified inner membrane complex (IMC proteins, localized correctly in these multi-headed parasites. These data suggest that MORN1 is essential for assembly of the basal complex, and that lack of the basal complex abolishes the contractile capacity assigned to the basal complex late in daughter formation. Consistent with this hypothesis we observe that MORN1 mutants fail to efficiently constrict and divide the apicoplast. We used the null background provided by the mutant to dissect the function of subdomains of the MORN1 protein. This demonstrated that deletion of a single MORN domain already prevented the function of MORN1 whereas a critical role for the short linker between MORN domains 6 and 7 was identified. In conclusion, MORN1 is required for basal complex assembly and loss of MORN1 results in defects in apicoplast division and daughter segregation.

  9. The morning morality effect: the influence of time of day on unethical behavior.

    Science.gov (United States)

    Kouchaki, Maryam; Smith, Isaac H

    2014-01-01

    Are people more moral in the morning than in the afternoon? We propose that the normal, unremarkable experiences associated with everyday living can deplete one's capacity to resist moral temptations. In a series of four experiments, both undergraduate students and a sample of U.S. adults engaged in less unethical behavior (e.g., less lying and cheating) on tasks performed in the morning than on the same tasks performed in the afternoon. This morning morality effect was mediated by decreases in moral awareness and self-control in the afternoon. Furthermore, the effect of time of day on unethical behavior was found to be stronger for people with a lower propensity to morally disengage. These findings highlight a simple yet pervasive factor (i.e., the time of day) that has important implications for moral behavior.

  10. Morning plasma cortisol is low among obese women with polycystic ovary syndrome.

    Science.gov (United States)

    Shabir, Iram; Ganie, Mohd Ashraf; Praveen, Edavan P; Khurana, Madan L; John, Jomimol; Gupta, Nandita; Kumar, Guresh; Ammini, Ariachery C

    2013-12-01

    Polycystic ovary syndrome (PCOS) is the most common cause for androgen excess in women. It is associated with wide variety of metabolic disorders. The present study assessed morning plasma cortisol in women with PCOS. One hundred and ninety seven cases and 55 controls were enrolled for this study. The mean age of patients and controls were 23 ± 5.6 years and 25 ± 4.3 years. One hundred twelve (56%) women with PCOS had BMI >25. Serum cortisol levels were significantly higher in lean PCOS women compared to controls (13.4 ± 5.1 versus 11.3 ± 4.5, p acne and hirsutism with increase in BMI. Morning plasma cortisol was lower among obese women with PCOS. Morning plasma cortisol correlated negatively with BMI in PCOS women with normal glucose tolerance.

  11. Istradefylline is recommended for morning use: a report of 4 cases.

    Science.gov (United States)

    Matsuura, Keita; Tomimoto, Hidekazu

    2015-01-01

    We herein describe four cases of patients with Parkinson's disease who were treated with istradefylline (ISD) in the evening and had severe daytime sleepiness. The time to onset of sleepiness varied between 2 weeks to 3 months. All patients recovered after changing the timing of the ISD dosage from evening to morning. ISD is an A2A receptor antagonist with a caffeine-like arousal effect that may worsen the quality of sleep and thus increase daytime sleepiness. This report provides the first evidence of daytime sleepiness induced by evening ISD treatment. We propose that ISD should therefore only be used in the morning, particularly if taken by professional drivers.

  12. Unilateral morning glory optic disc anomaly in a case with Down syndrome

    OpenAIRE

    Altun, Ahmet; Altun, Gulengul; Kurna, Sevda Aydin; Olcaysu, Osman Okan; Aki, Suat Fazil

    2014-01-01

    Background This case is unique because it is the first reported case of Down syndrome with morning glory optic disc anomaly in literature. Case presentation A 15-year-old girl with features of Down syndrome presented to the Clinic of Ophthalmology for a regular ophthalmologic examination. Her best corrected visual acuity was 20/50 in the right eye and 20/20 in the left eye. The fundus examination revealed findings compatible with unilateral morning glory optic disc anomaly in the right eye. T...

  13. Cost-effectiveness of modified-release prednisone in the treatment of moderate to severe rheumatoid arthritis with morning stiffness based on directly elicited public preference values

    Directory of Open Access Journals (Sweden)

    Dunlop W

    2013-10-01

    Full Text Available William Dunlop,1 Itrat Iqbal,1 Ifty Khan,2 Mario Ouwens,3 Louise Heron4 1Mundipharma International Limited, Cambridge, 2University College London, London, United Kingdom; 3Mapi HEOR, Houten, The Netherlands; 4Adelphi Values, Macclesfield, Cheshire, United Kingdom Background: Assessing the cost-effectiveness of treatments in rheumatoid arthritis (RA is of growing importance due to the chronic nature of the disease, rising treatment costs, and budget-constrained health care systems. This analysis assesses the cost-effectiveness of modified-release (MR prednisone compared with immediate-release (IR prednisone for the treatment of morning stiffness due to RA. Methods: A health state transition model was used to categorize RA patients into four health states, defined by duration of morning stiffness. The model applied a 1-year time horizon and adopted a UK National Health Service (NHS perspective. Health benefits were measured in quality-adjusted life years (QALYs and the final output was the incremental cost-effectiveness ratio (ICER. Efficacy data were derived from the CAPRA-1 (Circadian Administration of Prednisone in Rheumatoid Arthritis study, drug costs from the British National Formulary (BNF, and utility data from a direct elicitation time-trade-off (TTO study in the general population. Sensitivity analyses were conducted. Results: Mean treatment costs per patient were higher for MR-prednisone (£649.70 than for IR-prednisone (£46.54 for the duration of the model. However, the model generated an incremental QALY of 0.044 in favor of MR-prednisone which resulted in an ICER of £13,577. Deterministic sensitivity analyses did not lead to significant changes in the ICER. Probabilistic sensitivity analysis reported that MR-prednisone had an 84% probability of being cost-effective at a willingness-to-pay threshold of £30,000 per QALY. The model only considers drug costs and there was a lack of comparative long-term data for IR

  14. A Pareto Improving Strategy for the Time-Dependent Morning Commute Problem

    OpenAIRE

    Garcia, Reinaldo Crispiniano

    1999-01-01

    This dissertation describes a strategy which makes all commuters better off (i.e. a Pareto effecient strategy) for the time-dependent morning commute problem, even if the collected revenues are not returned to the population of commuters. The proposed strategy will apply road pricing as a tool for congestion management, a practice usually called congestion pricing. 

  15. Prognostic value of the morning blood pressure surge in 5645 subjects from 8 populations

    DEFF Research Database (Denmark)

    Li, Yan; Thijs, Lutgarde; Hansen, Tine W;

    2010-01-01

    Previous studies on the prognostic significance of the morning blood pressure surge (MS) produced inconsistent results. Using the International Database on Ambulatory Blood Pressure in Relation to Cardiovascular Outcome, we analyzed 5645 subjects (mean age: 53.0 years; 54.0% women) randomly recru...

  16. Phylogenetics and diversification of morning glories (tribe ipomoeeae, convolvulaceae) based on whole plastome sequences

    Science.gov (United States)

    Phylogenetic studies have demonstrated the largest morning glory genus, Ipomoea, is not monophyletic, and nine other segregate genera are derived from within Ipomoea. Therefore, systematic research is focused on the monophyletic tribe Ipomoeeae (c. 650-900 species). We used whole plastid genomes to ...

  17. Self-awakening improves alertness in the morning and during the day after partial sleep deprivation.

    Science.gov (United States)

    Ikeda, Hiroki; Kubo, Tomohide; Kuriyama, Kenichi; Takahashi, Masaya

    2014-12-01

    The ability to awaken at a predetermined time without an alarm is known as self-awakening. Self-awakening improves morning alertness by eliminating sleep inertia; however, the effects of self-awakening on daytime alertness and alertness that has deteriorated as a result of sleep loss are unknown. The aim of this study was to determine the effects of self-awakening on both morning and daytime alertness after partial sleep deprivation. Fifteen healthy males without the habit of self-awakening participated in a cross-over trial including forced awakening and self-awakening conditions. In each condition, participants' sleep was restricted to 5 h per night in their homes for 4 consecutive days. They completed a psychomotor vigilance task and subjective ratings of sleepiness immediately upon awakening each morning. On the fourth day, participants completed subjective ratings of sleepiness, a psychomotor vigilance task and sleep latency tests in the laboratory seven times at 1-h intervals during the day. The response speed on the psychomotor vigilance task, in the morning and during the day, was higher in the self-awakening than the forced awakening condition. Our results showed that self-awakening improved alertness (assessed by response speeds) by reducing sleep inertia and alleviated daytime sleepiness heightened by partial sleep deprivation.

  18. Morning and evening light treatment of seasonal affective disorder : response, relapse and prediction

    NARCIS (Netherlands)

    Meesters, Y.; Jansen, J.H.C.; Lambers, P.A.; Bouhuys, A.L.; Beersma, D.G.M.; Hoofdakker, R.H. van den

    Patients with seasonal affective disorder were randomly assigned to treatment with light in the morning (9.00-12.00 a.m.; n = 16; ML) or evening (6.00-9.00 p.m.; n = 11; EL). An intensive 24-day assessment procedure revealed the same response rates: 57% for ML, 50% for EL. During the rest of the

  19. Strengthening German Programs through Community Engagement and Partnerships with Saturday Morning Schools

    Science.gov (United States)

    Hellebrandt, Josef

    2014-01-01

    German university programs can increase enrollments and diversify their curricula through academic community partnerships with surrounding schools. This article informs about two community-supported initiatives between the German Studies Program at Santa Clara University and the South Bay Deutscher Schulverein, a Saturday Morning School in…

  20. Neuroticism and Morning Cortisol Secretion: Both Heritable, But No Shared Genetic Influences

    NARCIS (Netherlands)

    Riese, H; Rijsdijk, F.V.; Rosmalen, J.G.M.; Snieder, Harold; Ormel, J.

    2009-01-01

    Neuroticism is widely used as an explanatory concept in etiological research of psychopathology. To clarify what neuroticism actually represents, we investigated the phenotypic and genetic relationship between neuroticism and the morning cortisol secretion. In the current classic twin study, 125 fem

  1. Neuroticism and Morning Cortisol Secretion : Both Heritable, But No Shared Genetic Influences

    NARCIS (Netherlands)

    Riese, Harriette; Rijsdijk, Fruehling V.; Rosmalen, Judith G. M.; Snieder, Harold; Ormel, Johan

    2009-01-01

    Neuroticism is widely used as an explanatory concept in etiological research of psychopathology. To clarify what neuroticism actually represents, we investigated the phenotypic and genetic relationship between neuroticism and the morning cortisol secretion. In the current classic twin study, 125 fem

  2. Prognostic value of the morning blood pressure surge in 5645 subjects from 8 populations

    DEFF Research Database (Denmark)

    2010-01-01

    recruited in 8 countries. The sleep-through and the preawakening MS were the differences in the morning blood pressure with the lowest nighttime blood pressure and the preawakening blood pressure, respectively. We computed multivariable-adjusted hazard ratios comparing the risk in ethnic- and sex...

  3. Application of a Detailed Emission Model for Heavy Duty Diesel Engine Simulations Application d'un modèle détaillé d'émissions pour la simulation de gros moteurs diesel

    Directory of Open Access Journals (Sweden)

    Magnusson I.

    2006-12-01

    Full Text Available A detailed chemical model describing the formation of soot and NO is applied to simulate emission formation in a heavy duty diesel engine. Cylinder flow and spray development is simulated using an engine CFD code - Speedstar. Combustion is described using a simple eddy break-up model. Modeling of the emission-chemistry/turbulent-flow interaction is based on a flamelet approach. Contrary to a typical flamelet concept, transport equations are solved for mass fractions of soot and NO. The reason being that these major emission constituencies are assumed to change slowly in comparison to typical time scales for chemical processes or transport processes important for combustion. Chemical reactions leading to production and destruction of soot and NO are, however, assumed to be fast. Soot and NO source terms are therefore evaluated from a flamelet library using a presumed probability density function and integrating over mixture fraction space. Results from simulations are compared to engine measurements inform of exhaust emission data and cylinder pressure. Un modèle avec chimie détaillée décrivant la formation des suies et du NO est appliqué à la simulation de la formation des polluants dans un gros moteur Diesel. L'écoulement et le spray sont modélisés avec le code de calcul Speedstar. La combustion est représentée par le modèle eddy break-up . La modélisation de l'interaction entre l'écoulement turbulent et la chimie des polluants est basée sur une approche de type flamelet . Cependant, à la différence d'autres travaux, des équations de transport pour les fractions massiques de suies et de NO sont résolues. Cela est justifié par la supposition que les temps caractéristiques de formation de ces composés sont longs comparés à ceux associés aux phénomènes de transport et aux réactions chimiques associées à la combustion. Cependant, les vitesses de réaction se rapportant aux suies et au NO sont supposées rapides. Cela

  4. The return to the USA of doxylamine-pyridoxine delayed release combination (Diclegis®) for morning sickness--a new morning for American women.

    Science.gov (United States)

    Koren, Gideon

    2013-01-01

    The US FDA approval in April 2013 of Diclegis®, the doxylamine-pyridoxine combination for morning sickness, is a major milestone, particularly since it is indicated for use in pregnancy and the FDA has labeled it a pregnancy category A drug the strongest evidence of fetal safety. After thirty years of being orphaned from an FDA-labeled drug for the most common medical condition in pregnancy, American women and their health care providers have a therapeutic solution that is likely to positively impact millions of women each year. This review highlights the milestones of this antiemetic agent over the last 40 years.

  5. Nighttime feeding likely alters morning metabolism but not exercise performance in female athletes.

    Science.gov (United States)

    Ormsbee, Michael J; Gorman, Katherine A; Miller, Elizabeth A; Baur, Daniel A; Eckel, Lisa A; Contreras, Robert J; Panton, Lynn B; Spicer, Maria T

    2016-07-01

    The timing of morning endurance competition may limit proper pre-race fueling and resulting performance. A nighttime, pre-sleep nutritional strategy could be an alternative method to target the metabolic and hydrating needs of the early morning athlete without compromising sleep or gastrointestinal comfort during exercise. Therefore, the purpose of this investigation was to examine the acute effects of pre-sleep chocolate milk (CM) ingestion on next-morning running performance, metabolism, and hydration status. Twelve competitive female runners and triathletes (age, 30 ± 7 years; peak oxygen consumption, 53 ± 4 mL·kg(-1)·min(-1)) randomly ingested either pre-sleep CM or non-nutritive placebo (PL) ∼30 min before sleep and 7-9 h before a morning exercise trial. Resting metabolic rate (RMR) was assessed prior to exercise. The exercise trial included a warm-up, three 5-min incremental workloads at 55%, 65%, and 75% peak oxygen consumption, and a 10-km treadmill time trial (TT). Physiological responses were assessed prior, during (incremental and TT), and postexercise. Paired t tests and magnitude-based inferences were used to determine treatment differences. TT performances were not different ("most likely trivial" improvement with CM) between conditions (PL: 52.8 ± 8.4 min vs CM: 52.8 ± 8.0 min). RMR was "likely" increased (4.8%) and total carbohydrate oxidation (g·min(-1)) during exercise was "possibly" or likely increased (18.8%, 10.1%, 9.1% for stage 1-3, respectively) with CM versus PL. There were no consistent changes to hydration indices. In conclusion, pre-sleep CM may alter next-morning resting and exercise metabolism to favor carbohydrate oxidation, but effects did not translate to 10-km running performance improvements.

  6. Morning Sickness

    Science.gov (United States)

    ... report card Careers Archives Pregnancy Before or between pregnancies Nutrition, weight & fitness Prenatal care Is it safe? Labor & ... Careers Archives Health Topics Pregnancy Before or between pregnancies Nutrition, weight & fitness Prenatal care Is it safe? Labor & ...

  7. Morning Sunshine

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    As the capital city of the last dynasties in the history of China,Beijing developed a com- plicated fortification system,consisting of city walls,gates,watchtowers and moats.Although most of the defense architecture has been dismantled to make way for modern infrastructure, some old names still stay with the city.Chaoyang District in the northeasteru part of the city proper earns its name from the east gate of the ancient inner city:Chaoyang Gate.

  8. Morning sickness

    Science.gov (United States)

    ... of protein and carbohydrates. Try peanut butter on apple slices or celery; nuts; cheese and crackers; and ... stomach. You may have to try several different brands of prenatal vitamins before finding one you can ...

  9. Morning sickness

    Science.gov (United States)

    ... and complex carbohydrates, such as peanut butter on apple slices or celery; nuts; cheese; crackers; milk; cottage ... Pregnancy Browse the Encyclopedia A.D.A.M., Inc. is accredited by URAC, also known as the ...

  10. Morning glory disc anomaly, midline cranial defects and abnormal carotid circulation: an association worth looking for

    Energy Technology Data Exchange (ETDEWEB)

    Quah, Boon Long [Kandang Kerbau Women' s and Children' s Hospital, Singapore National Eye Centre, Department of Ophthalmology (Singapore); Hamilton, Jill [Hospital for Sick Children, Department of Paediatrics, Toronto, ON (Canada); Blaser, Susan [Hospital for Sick Children, Department of Diagnostic Imaging, Toronto, ON (Canada); Heon, Elise; Tehrani, Nasrin N. [Hospital for Sick Children, Department of Ophthalmology and Vision Sciences, Toronto, ON (Canada)

    2005-05-01

    We report on a 4-year-old boy who presented to the ophthalmology department for assessment of convergent strabismus. Ophthalmic examination showed a left morning glory optic disc anomaly and retinal detachment. Plain films obtained for investigation of short stature prior to ophthalmic examination revealed delayed bone age. Ophthalmological findings prompted CT and MRI imaging and angiographic investigations. Midline cranial defects and abnormal carotid circulation were identified. These findings may be associated with morning glory optic disc anomaly, and their association is often under-recognized. It is important that clinicians and radiologists be aware of this spectrum of disorders, as the vascular abnormalities may predispose the patient to transient ischemic attacks and strokes. Growth delay may result from hypopituitarism. (orig.)

  11. Morning and evening personality characteristics in a sample of young Italians.

    Science.gov (United States)

    Cavallera, G M; Giampietro, M

    2007-02-01

    The goal of this study was to investigate associations of morning and evening personality types with personality dimensions in a convenient sample of 60 men and 60 women, ages 18 to 29 years. A short form of the Morningness-Eveningness Questionnaire and a personality questionnaire Come mi vedo (How I see myself), based on the 5-factor model of personality, were given. Several personality dimensions appear to be significantly correlated with Morningness scores: Conscientiousness (positively) and Openmindedness (negatively). The analysis indicated morning types tend to reach their goals resolutely and to plan their steps, they prefer to be precise, tidy, punctual, trustworthy; they have a sense of duty and responsibility; they are also less original and less open to culture and novelties, less curious, conformist, traditionalist, and less well-informed, hardworking, steady, tenacious, and diligent, on the Come mi vedo.

  12. The pathogenesis of retinal detachment with morning glory disc and optic pit.

    Science.gov (United States)

    Irvine, A R; Crawford, J B; Sullivan, J H

    1986-01-01

    A child with nonrhegmatogenous retinal detachment associated with morning glory disc underwent first a vitrectomy and then, some months later, an optic nerve sheath fenestration. The latter procedure led to retinal reattachment. It also produced a biopsy specimen that confirmed the perineural herniation of poorly differentiated retinal tissue in this condition, similar to that in congenital pit of the optic nerve. It demonstrated continuity of the vitreous cavity with the perineural space, both histologically and by the fact that gas injected through the pars plana into the vitreous cavity bubbled out the window in the optic nerve sheath. The authors suggest that morning glory disc and optic pit share similar anatomic features, differing more in degree than in kind, and that the porous nature of the poorly differentiated tissue herniated around the optic nerve into the subarachnoid space in these conditions makes several sources of subretinal fluid possible.

  13. Changing Family Practices with Assistive Technology: MOBERO Improves Morning and Bedtime Routines for Children with ADHD

    DEFF Research Database (Denmark)

    Sonne, Tobias; Müller, Jörg; Marshall, Paul;

    ’ frustration levels. Additionally, use of MOBERO was associated with a 16.5% reduction in core ADHD symptoms and an 8.3% improvement in the child’s sleep habits, both measured by standardized questionnaires. Our study highlights the potential of assistive technologies to change the everyday practices......Families of children with Attention Deficit Hyperactivity Disorder (ADHD) often report morning and bedtime routines to be stressful and frustrating. Through a design process involving domain professionals and families we designed MOBERO, a smartphone-based system that assists families...... in establishing healthy morning and bedtime routines with the aim to assist the child in becoming independent and lowering the parents’ frustration levels. In a two-week intervention with 13 children with ADHD and their families, MOBERO significantly improved children’s independence and reduced parents...

  14. A low glycaemic index breakfast cereal preferentially prevents children's cognitive performance from declining throughout the morning.

    Science.gov (United States)

    Ingwersen, Jeanet; Defeyter, Margaret Anne; Kennedy, David O; Wesnes, Keith A; Scholey, Andrew B

    2007-07-01

    This study investigated whether the glycaemic index (GI) of breakfast cereal differentially affects children's attention and memory. Using a balanced cross-over design, on two consecutive mornings 64 children aged 6-11 years were given a high GI cereal and a low GI cereal in a counterbalanced order. They performed a series of computerised tests of attention and memory, once prior to breakfast and three times following breakfast at hourly intervals. The results indicate that children's performance declines throughout the morning and that this decline can be significantly reduced following the intake of a low GI cereal as compared with a high GI cereal on measures of accuracy of attention (M=-6.742 and -13.510, respectively, p<0.05) and secondary memory (M=-30.675 and -47.183, respectively, p<0.05).

  15. Detection of Early Morning Daily Activities with Static Home and Wearable Wireless Sensors

    Directory of Open Access Journals (Sweden)

    David Vanderpool

    2007-10-01

    Full Text Available This paper describes a flexible, cost-effective, wireless in-home activity monitoring system for assisting patients with cognitive impairments due to traumatic brain injury (TBI. The system locates the subject with fixed home sensors and classifies early morning bathroom activities of daily living with a wearable wireless accelerometer. The system extracts time- and frequency-domain features from the accelerometer data and classifies these features with a hybrid classifier that combines Gaussian mixture models and a finite state machine. In particular, the paper establishes that despite similarities between early morning bathroom activities of daily living, it is possible to detect and classify these activities with high accuracy. It also discusses system training and provides data to show that with proper feature selection, accurate detection and classification are possible for any subject with no subject specific training.

  16. Morning blood pressure surge and arterial stiffness in newly diagnosed hypertensive patients.

    Science.gov (United States)

    Kıvrak, Ali; Özbiçer, Süleyman; Kalkan, Gülhan Yüksel; Gür, Mustafa

    2017-06-01

    We aimed to investigate the relationship between the morning blood pressure (BP) surge and arterial stiffness in patients with newly diagnosed hypertension. Three hundred and twenty four (mean age 51.7 ± 11.4 years) patients who had newly diagnosed hypertension with 24 h ambulatory BP monitoring were enrolled. Parameters of arterial stiffness, pulse wave velocity and augmentation index (Aix) were measured by applanation tonometry and aortic distensibility was calculated by echocardiography. Compared with the other groups, pulse wave velocity, day-night systolic BP (SBP) difference (p arterial stiffness which is a surrogate endpoint for cardiovascular diseases. The inverse relationship between morning BP surge and aortic distensibility and direct relation found in our study is new to the literature.

  17. Neuroticism and Morning Cortisol Secretion: Both Heritable, But No Shared Genetic Influences

    OpenAIRE

    Riese, Harriette; Rijsdijk, Fruehling V.; Rosmalen, Judith G. M.; Snieder, Harold; Ormel, Johan

    2009-01-01

    Neuroticism is widely used as an explanatory concept in etiological research of psychopathology. To clarify what neuroticism actually represents, we investigated the phenotypic and genetic relationship between neuroticism and the morning cortisol secretion. In the current classic twin study, 125 female twin pairs (74 monozygotic and 51 dizygotic pairs) participated. For each participant, 4 different neuroticism scores were available to calculate a neuroticism composite score that was used in ...

  18. A cereal-based evening meal rich in indigestible carbohydrates increases plasma butyrate the next morning

    DEFF Research Database (Denmark)

    Nilsson, Anne C; Östman, Elin M; Knudsen, Knud Erik Bach

    2010-01-01

    , mean ± SD: 25.9 ± 3.2 y, BMI consumed all test meals in a random order on separate evenings. At a standardized breakfast following evening test meals...... concentrations the following morning compared with an evening meal with white wheat bread (P involving colonic fermentation and generation of SCFA, where in particular...... butyric acid may be involved. This mechanism may be one explanation by which whole grain is protective against type 2 diabetes and cardiovascular disease....

  19. Awake at 4 a.m.: Treatment of Insomnia With Early Morning Awakenings Among Older Adults

    OpenAIRE

    Fiorentino, Lavinia; Martin, Jennifer L.

    2010-01-01

    Insomnia is a common problem among older adults. In particular, older adults experience insomnia coupled with early morning awakenings due to an interaction between age-related changes in circadian rhythm timing coupled with behavior changes that contribute to sustained poor sleep. Cognitive–behavioral therapy for insomnia (CBT-I), at times coupled with circadian interventions (e.g., timed light exposure), are likely to be most successful in optimizing sleep quality. In delivering CBT-I to ol...

  20. Transcriptome Profiling of Beach Morning Glory (Ipomoea imperati under Salinity and Its Comparative Analysis with Sweetpotato.

    Directory of Open Access Journals (Sweden)

    Julio Solis

    Full Text Available The response and adaption to salt remains poorly understood for beach morning glory [Ipomoea imperati (Vahl Griseb], one of a few relatives of sweetpotato, known to thrive under salty and extreme drought conditions. In order to understand the genetic mechanisms underlying salt tolerance of a Convolvulaceae member, a genome-wide transcriptome study was carried out in beach morning glory by 454 pyrosequencing. A total of 286,584 filtered reads from both salt stressed and unstressed (control root and shoot tissues were assembled into 95,790 unigenes with an average length of 667 base pairs (bp and N50 of 706 bp. Putative differentially expressed genes (DEGs were identified as transcripts overrepresented under salt stressed tissues compared to the control, and were placed into metabolic pathways. Most of these DEGs were involved in stress response, membrane transport, signal transduction, transcription activity and other cellular and molecular processes. We further analyzed the gene expression of 14 candidate genes of interest for salt tolerance through quantitative reverse transcription PCR (qRT-PCR and confirmed their differential expression under salt stress in both beach morning glory and sweetpotato. The results comparing transcripts of I. imperati against the transcriptome of other Ipomoea species, including sweetpotato are also presented in this study. In addition, 6,233 SSR markers were identified, and an in silico analysis predicted that 434 primer pairs out of 4,897 target an identifiable homologous sequence in other Ipomoea transcriptomes, including sweetpotato. The data generated in this study will help in understanding the basics of salt tolerance of beach morning glory and the SSR resources generated will be useful for comparative genomics studies and further enhance the path to the marker-assisted breeding of sweetpotato for salt tolerance.

  1. Effects of cereal bars for breakfast and mid-morning snacks on mood and memory.

    Science.gov (United States)

    Smith, Andrew P; Wilds, Amanda

    2009-01-01

    The aim of the present study was to examine the effects of consuming cereal bars, given either for breakfast or a mid-morning snack, on mood and memory. Thirty-two volunteers (16 males, 16 females; mean age, 20 years 9 months) were randomly assigned to one of four groups formed by combining breakfast (cereal bar versus no breakfast) and snack (cereal bar versus no snack) conditions. A baseline session was completed at 08:30 h followed by breakfast at 9:00 h, another test at 10:00 h, followed by a mid-morning snack and then a final test at 12:00 h. In each session, volunteers rated their mood and carried out four memory tasks: free recall; recognition memory; a verbal reasoning task; and a semantic processing task. The results showed that volunteers who consumed a cereal bar for breakfast felt more alert, happy and sociable and less anxious. In addition, they also recalled more words in a free recall task. When the cereal bar was consumed as a mid-morning snack, alertness and hedonic tone increased, especially in the group who received no breakfast. The group who had no breakfast reported reduced anxiety after consumption of the snack. Recall was also improved after the snack. These findings show that consuming cereal bars in the early and mid-morning leads to beneficial behavioural effects. The results confirm earlier research on effects of breakfast and extend our knowledge of effects of snacks. Consumption of cereal bars may have important practical applications especially in situations where preparation of breakfast is difficult.

  2. Orbitofrontal Gray Matter Relates to Early Morning Awakening: A Neural Correlate of Insomnia Complaints?

    OpenAIRE

    Stoffers, Diederick; Moens, Sarah; Benjamins, Jeroen; van Tol, Marie-José; Penninx, Brenda W. J. H.; Veltman, Dick J.; van der wee, Nic J. A.; Van Someren, Eus J.W.

    2012-01-01

    Sleep complaints increase profoundly with age; prevalence estimates of insomnia in the elderly reach up to 37%. The three major types of nocturnal complaints are difficulties initiating (DIS) and maintaining (DMS) sleep and early morning awakening (EMA), of which the latter appears most characteristic for aging. The neural correlates associated with these complaints have hardly been investigated, hampering the development of rational treatment and prevention. A recent study on structural brai...

  3. Characterization of a novel gravitropic mutant of morning glory, weeping2

    Science.gov (United States)

    Kitazawa, Daisuke; Miyazawa, Yutaka; Fujii, Nobuharu; Nitasaka, Eiji; Takahashi, Hideyuki

    2008-09-01

    In higher plants, gravity is a major environmental cue that governs growth orientation, a phenomenon termed gravitropism. It has been suggested that gravity also affects other aspects of morphogenesis, such as circumnutation and winding movements. Previously, we showed that these aspects of plant growth morphology require amyloplast sedimentation inside gravisensing endodermal cells. However, the molecular mechanism of the graviresponse and its relationship to circumnutation and winding remains obscure. Here, we have characterized a novel shoot gravitropic mutant of morning glory, weeping2 ( we2). In the we2 mutant, the gravitropic response of the stem was absent, and hypocotyls exhibited a severely reduced gravitropic response, whereas roots showed normal gravitropism. In agreement with our previous studies, we found that we2 mutant has defects in shoot circumnutation and winding. Histological analysis showed that we2 mutant forms abnormal endodermal cells. We identified a mutation in the morning glory homolog of SHORT-ROOT ( PnSHR1) that was genetically linked to the agravitropic phenotype of we2 mutant, and which may underlie the abnormal differentiation of endodermal cells in this plant. These results suggest that the phenotype of we2 mutant is due to a mutation of PnSHR1, and that PnSHR1 regulates gravimorphogenesis, including circumnutation and winding movements, in morning glory.

  4. Are neuroticism and extraversion related to morning cortisol release in healthy older people?

    Science.gov (United States)

    Puig-Perez, Sara; Almela, Mercedes; Pulopulos, Matías M; Hidalgo, Vanesa; Salvador, Alicia

    2016-12-01

    The cortisol awakening response (CAR) is a discrete component of the hypothalamic-pituitary-adrenal axis (HPA-axis) function that has been widely related to both health and some personality traits. There is evidence that neuroticism and extraversion affect health and well-being and play a damaging or protective role, respectively. In this study, we aimed to explore the relationship between these personality dimensions and morning cortisol concentrations in people aged 55 or older. To do so, morning saliva samples were collected on two consecutive weekdays from a total of 160 older men and women. Neuroticism and extraversion were assessed using the Eysenck Personality Questionnaire-Revised, short form (EPQ-RS). Our results showed that neuroticism was negatively related to overall morning cortisol concentrations (AUCG) (i.e., area under the curve with respect to the ground in cortisol levels), but not to the CAR. When we explored sex as a moderator, neuroticism was related to a CAR of increased magnitude in women, although this relationship was not significant in men. No significant relationships were found between extraversion and CAR or AUCG, regardless of sex. In conclusion, neuroticism - but not extraversion - was related to HPA-axis function in older adults, highlighting its potential relevance in health alterations associated with HPA-axis functioning.

  5. Morning Frost in Trench Dug by Phoenix, Sol 113 (False Color)

    Science.gov (United States)

    2008-01-01

    This image from the Surface Stereo Imager on NASA's Phoenix Mars Lander shows morning frost inside the 'Snow White' trench dug by the lander, in addition to subsurface ice exposed by use of a rasp on the floor of the trench. The camera took this image at about 9 a.m. local solar time during the 113th Martian day of the mission (Sept. 18, 2008). Bright material near and below the four-by-four set of rasp holes in the upper half of the image is water-ice exposed by rasping and scraping in the trench earlier the same morning. Other bright material especially around the edges of the trench, is frost. Earlier in the mission, when the sun stayed above the horizon all night, morning frost was not evident in the trench. This image is presented in false color that enhances the visibility of the frost. The trench is 4 to 5 centimeters (about 2 inches) deep, about 23 centimeters (9 inches) wide. Phoenix landed on a Martian arctic plain on May 25, 2008. The mission is led by the University of Arizona, Tucson, on behalf of NASA. Project management of the mission is led by NASA's Jet Propulsion Laboratory, Pasadena, Calif. Spacecraft development was by Lockheed Martin Space Systems, Denver.

  6. Effects of morning rise in cortisol concentration on regulation of lipolysis in subcutaneous adipose tissue.

    Science.gov (United States)

    Samra, J S; Clark, M L; Humphreys, S M; Macdonald, I A; Matthews, D R; Frayn, K N

    1996-12-01

    Cortisol has a well-defined circadian rhythm. The aim of the study was to examine the effect of the morning rise in cortisol concentration on lipolysis in adipose tissue. Ten healthy subjects were studied on two occasions, and six of these were studied on three occasions. During the first two occasions, either a control or cortisol suppression study was performed by using metyrapone, and on the third occasion exogenous cortisol replacement was given in addition to metyrapone. Lipolysis in the subcutaneous adipose tissue of the anterior abdominal wall was studied by measurement of arteriovenous differences. Reduction in the early morning rise in cortisol led to significantly decreased venoarterialized differences for nonesterified fatty acids (P adipose tissue. At the same time the arterialized plasma triacylglycerol concentration increased (P adipose lipoprotein lipase (EC 3.1.1.34) rate of action (P effects on lipolysis. We conclude that the morning rise in plasma cortisol concentration plays an important role in the regulation of lipolysis in adipose tissue in normal healthy adults.

  7. [Nutritional analysis of breakfast on rising and mid-morning snack in a college population].

    Science.gov (United States)

    Durá Travé, T

    2013-01-01

    To carry out a descriptive study on the breakfast model in a college population and to analyze the energy and nutrients provided, in connection with established nutritional requirements. Registry of food intake for breakfast (on rising and mid-morning snack) of a school day in a sample of 740 college students (286 men and 454 women) with ages ranging 19-24 years. Gender, age, weight, height, and body mass index, and type of residence were collected from each interviewee. Percentages intakes of nutrients have been calculated in proportion to established dietary recommendations (%IR). 93.2% had breakfast on rising and 83.8% took a mid-morning snack daily, and 53.5% do both intakes. The most common foods were dairy products (92.6%), cereals (58.8%) and sweet food (57.9%) at breakfast, and cereals (46.6%), fruits (40.7%) and sausages (34.9%) at mid-morning. The %IR of the calorie intake was 24.4% in males and 24.6% in females (n.s.). The %IR of the cholesterol intake was 38.2% in males and 23.9% in females (p academic performance. Copyright © AULA MEDICA EDICIONES 2013. Published by AULA MEDICA. All rights reserved.

  8. Cytokine gene associations with self-report ratings of morning and evening fatigue in oncology patients and their family caregivers.

    Science.gov (United States)

    Dhruva, Anand; Aouizerat, Bradley E; Cooper, Bruce; Paul, Steven M; Dodd, Marylin; West, Claudia; Wara, William; Lee, Kathryn; Dunn, Laura B; Langford, Dale J; Merriman, John D; Baggott, Christina; Cataldo, Janine; Ritchie, Christine; Kober, Kord M; Leutwyler, Heather; Miaskowski, Christine

    2015-03-01

    The purpose of this study was to evaluate for differences in variations in pro- and anti-inflammatory cytokine genes between participants who were classified as having low and high levels of morning and evening fatigue and to evaluate for differences in phenotypic characteristics between these two groups. In a sample of 167 oncology outpatients with breast, prostate, lung, or brain cancer and 85 of their family caregivers, growth mixture modeling was used to identify latent classes of individuals based on ratings of morning and evening fatigue obtained prior to, during, and for 4 months following completion of radiation therapy. Differences in single nucleotide polymorphisms and haplotypes in 15 cytokine genes were evaluated between the latent classes. Multiple logistic regression was used to assess the effect of phenotypic and genotypic characteristics on morning and evening fatigue class membership. Associations were found between morning fatigue and number of comorbidities as well as variations in tumor necrosis factor alpha (TNFA) rs1800629 and rs3093662. Evening fatigue was associated with caring for children at home and variations in interleukin 4 (IL4) rs2243248 and TNFA rs2229094. Younger age and lower performance status were associated with both morning and evening fatigue. These findings suggest that inflammatory mediators are associated with the development of morning and evening fatigue. However, because different phenotypic characteristics and genomic markers are associated with diurnal variations in fatigue, morning and evening fatigue may be distinct but related symptoms.

  9. Insufficient duration of action of antihypertensive drugs mediates high blood pressure in the morning in hypertensive population: the Ohasama study.

    Science.gov (United States)

    Chonan, Kenichi; Hashimoto, Junichiro; Ohkubo, Takayoshi; Tsuji, Ichiro; Nagai, Kenichi; Kikuya, Masahiro; Hozawa, Atsushi; Matsubara, Mitsunobu; Suzuki, Michiko; Fujiwara, Tohru; Araki, Tsutomu; Satoh, Hiroshi; Hisamichi, Shigeru; Imai, Yutaka

    2002-05-01

    Blood pressure (BP) usually peaks in the morning. The circadian variation of the onset of cardiovascular disease mimics this circadian BP variation. To examine the determinants of the BP difference between the self-recorded BP in the morning (home BP) and daytime average ambulatory BP a cross sectional study was done in the general population of Ohasama, Japan. 1207 subjects > or = 20 years measured both home (more than 14 times) and ambulatory BPs (326 treated for hypertension and 881 untreated subjects), The prevalence of subjects with the systolic BP difference (home BP in the morning - daytime ambulatory BP) of > or = 10 mmHg (high morning BP) was 5.6% in untreated normotensives, 2.9% in untreated hypertensives, and 25.8% in treated hypertensives. This trend was also observed for diastolic pressure. Multiple regression analysis demonstrated that age, male sex, and use of antihypertensive drugs were positively associated and day-night difference of BP was negatively associated with the high morning BP, respectively. These results suggest an insufficient duration of antihypertensive action of widely used antihypertensive drugs in Japan from the 1980s to 1990s. The amplitude of the day-night difference of ambulatory BP in subjects with a high morning BP was lower (non-dipping) than that without high morning BP. The high morning BP is not necessarily accompanied by hypertension but might be mediated, at least in part, by an insufficient duration of action of antihypertensive drugs. The high morning BP accompanies so-called non-dipper pattern of circadian BP variation. An insufficient duration of action of drugs may partly mediate non-dipping in subjects with antihypertensive medication.

  10. The role of dew as a night-time reservoir and morning source for atmospheric ammonia

    Science.gov (United States)

    Wentworth, Gregory R.; Murphy, Jennifer G.; Benedict, Katherine B.; Bangs, Evelyn J.; Collett, Jeffrey L., Jr.

    2016-06-01

    Several field studies have proposed that the volatilization of NH3 from evaporating dew is responsible for an early morning pulse of ammonia frequently observed in the atmospheric boundary layer. Laboratory studies conducted on synthetic dew showed that the fraction of ammonium (NH4+) released as gas-phase ammonia (NH3) during evaporation is dependent on the relative abundances of anions and cations in the dew. Hence, the fraction of NH3 released during dew evaporation (Frac(NH3)) can be predicted given dew composition and pH. Twelve separate ambient dew samples were collected at a remote high-elevation grassland site in Colorado from 28 May to 11 August 2015. Average [NH4+] and pH were 26 µM and 5.2 respectively and were on the lower end of dew [NH4+] and pH observations reported in the literature. Ambient dew mass (in g m-2) was monitored with a dewmeter, which continuously measured the mass of a tray containing artificial turf representative of the grass canopy to track the accumulation and evaporation of dew. Simultaneous measurements of ambient NH3 indicated that a morning increase in NH3 was coincident in time with dew evaporation and that either a plateau or decrease in NH3 occurred once the dew had completely evaporated. This morning increase in NH3 was never observed on mornings without surface wetness (neither dew nor rain, representing one-quarter of mornings during the study period). Dew composition was used to determine an average Frac(NH3) of 0.94, suggesting that nearly all NH4+ is released back to the boundary layer as NH3 during evaporation at this site. An average NH3 emission of 6.2 ng m-2 s-1 during dew evaporation was calculated using total dew volume (Vdew) and evaporation time (tevap) and represents a significant morning flux in a non-fertilized grassland. Assuming a boundary layer height of 150 m, the average mole ratio of NH4+ in dew to NH3 in the boundary layer at sunrise is roughly 1.6 ± 0.7. Furthermore, the observed loss of NH3 during

  11. Status of home blood pressure measured in morning and evening: evaluation in normotensives and hypertensives in Japanese urban population.

    Science.gov (United States)

    Kawabe, Hiroshi; Saito, Ikuo; Saruta, Takao

    2005-06-01

    To assess home blood pressure status in a Japanese urban population, we analyzed home blood pressure values in normotensive subjects determined by casual blood pressure (mmHg), hypertensive subjects without medication (> or = 140/90 mmHg) and treated hypertensive patients. The subjects (468 male, 232 female; mean age 41 years old) were recruited from a company located in Tokyo. Home blood pressure was measured with a semi-automatic device (Omron HEM-759P). Subjects were instructed to perform triplicate morning and evening measurements on 7 consecutive days. In the treated hypertensive group (n = 70), there was a significant difference between morning (139 +/- 12/88 +/- 9 mmHg) and evening (130 +/- 12/79 +/- 8 mmHg) home blood pressure. In the normotensive group (n = 558), however, only the diastolic blood pressure (DBP) component of the home blood pressure was significantly different between morning (115 +/- 13/72 +/- 9 mmHg) and evening (114 +/- 12/68 +/- 8 mmHg). In the nontreated hypertensive group (n = 72), casual blood pressure (145 +/- 14/92 +/- 9 mmHg) was higher than morning (138 +/- 16/89 +/- 11 mmHg) and evening (134 +/- 16/83 +/- 11 mmHg) home blood pressure, but no difference was seen between morning and evening systolic blood pressure (SBP). According to the reference value of the Japanese Society of Hypertension 2004 (SBP > or = 135 mmHg and/or DBP > or = 85 mmHg), 7.2% (systolic) and 8.7% (diastolic) of subjects in the normotensive group were classified as hypertensive by home blood pressure. Casual blood pressure in the treated hypertensive group was normal in 64.3% for SBP and 70.0% for DBP. However, their morning SBP (32.9%), morning DBP (40.0%), evening SBP (10.0%), and evening DBP (17.1%) were classified as hypertensive by home blood pressure. Furthermore, patients who were taking antihypertensive drug(s) only in the morning (n = 52) showed higher morning SBP (6 mmHg, p = 0.086) and morning DBP (6 mmHg, p = 0.005) than patients taking drug(s) by

  12. The role of breakfast and a mid-morning snack on the ability of children to concentrate at school.

    Science.gov (United States)

    Benton, David; Jarvis, Megan

    2007-02-28

    The effect on the ability of children to attend to their school work, of the size of breakfast and whether a mid-morning snack had been consumed, was considered. Nine year old children were studied for four days. They reported what they had eaten for breakfast and days when they either had or had not eaten a mid-morning snack were contrasted. For an hour in the late morning, while performing individual work, activity sampling was used to establish the time spent on task. Those who had eaten a small breakfast, on average 61 kcal, spent significantly less time attending to their work than those who had eaten larger meals. The adverse effect of a small breakfast was reversed by the consumption of a mid-morning snack.

  13. Relationship of Morning Cortisol to Circadian Phase and Rising Time in Young Adults with Delayed Sleep Times

    Directory of Open Access Journals (Sweden)

    Mark S. Rea

    2012-01-01

    Full Text Available The present study was aimed at further elucidating the relationship between circadian phase, rising time, and the morning cortisol awakening response (CAR. The results presented here are a secondary analysis of experimental data obtained from a study of advanced sleep-wake schedules and light exposures on circadian phase advances measured by dim-light melatonin onset (DLMO. The present results demonstrate that morning CAR is strongly related to rising time and more weakly related to DLMO phase.

  14. Effects of a late supper on digestion and the absorption of dietary carbohydrates in the following morning

    OpenAIRE

    Tsuchida, Yukie; Hata, Sawa; Sone, Yoshiaki

    2013-01-01

    Background Our previous experiment showed that the light intensity exposed on the subjects during evening time had no effect in the following morning on the efficiency of the digestion and absorption of dietary carbohydrates ingested at a usual suppertime. People who keep late hours usually have a late suppertime; thus, we examined the effects of a late suppertime on gastrointestinal activity in the following morning in comparison to that of a usual suppertime. Methods Twelve female universit...

  15. Verification of impact of morning showering and mist sauna bathing on human physiological functions and work efficiency during the day

    Science.gov (United States)

    Lee, Soomin; Fujimura, Hiroko; Shimomura, Yoshihiro; Katsuura, Tetsuo

    2015-09-01

    Recently, a growing number in Japan are switching to taking baths in the morning (morning bathing). However, the effects of the morning bathing on human physiological functions and work efficiency have not yet been revealed. Then, we hypothesized that the effect of morning bathing on physiological functions would be different from those of night bathing. In this study, we measured the physiological functions and work efficiency during the day following the morning bathing (7:10-7:20) including showering, mist sauna bathing, and no bathing as a control. Ten male healthy young adults participated in this study as the subjects. We evaluated the rectal temperature (Tre), skin temperature (Tsk), heart rate (HR), heart rate variability (HRV), blood pressure (BP), the relative power density of the alpha wave (α-wave ratio) of electroencephalogram, alpha attenuation coefficient (AAC), and the error rate of the task performance. As a result, we found that the HR after the mist sauna bathing was significantly lower than those after no bathing rest 3 (11:00). Furthermore, we verified that the α-wave ratio of the Pz after the mist sauna bathing was significantly lower than those after no bathing during the task 6 (15:00). On the other hand, the α-wave ratio of the Pz after the mist sauna bathing was significantly higher than those after showering during the rest 3 (11:00). Tsk after the mist sauna bathing was higher than those after the showering at 9:00 and 15:00. In addition, the error rate of the task performance after the mist sauna bathing was lower than those after no bathing and showering at 14:00. This study concludes that a morning mist sauna is safe and maintains both skin temperature compared to other bathing methods. Moreover, it is presumed that the morning mist sauna bathing improves work efficiency comparing other bathing methods during the task period of the day following the morning bathing.

  16. How to deal with morning bad breath: A randomized, crossover clinical trial

    Directory of Open Access Journals (Sweden)

    Jeronimo M Oliveira-Neto

    2013-01-01

    Full Text Available Context: The absence of a protocol for the treatment of halitosis has led us to compare mouthrinses with mechanical oral hygiene procedures for treating morning breath by employing a hand-held sulfide monitor. Aims: To compare the efficacy of five modalities of treatment for controlling morning halitosis in subjects with no dental or periodontal disease. Settings and Design: This is a five-period, randomized, crossover clinical trial. Materials and Methods: Twenty volunteers were randomly assigned to the trial. Testing involved the use of a conventional tongue scraper, a tongue scraper joined to the back of a toothbrush′s head, two mouthrinses (0.05% cetylpyridinium chloride and 0.12% chlorhexidine digluconate and a soft-bristled toothbrush and fluoride toothpaste for practicing oral hygiene. Statistical Analysis Used: Data analysis was performed using SPSS version 17 for Windows and NCSS 2007 software (P < 0.05. The products and the periods were compared with each other using the Friedman′s test. When significant differences (P < 0.05 were determined, the products and periods were compared in pairs by using the Wilcoxon′s test and by adjusting the original significance level (0.05 for multiple comparisons by using the Bonferroni′s method. Results: The toothbrush′s tongue scraper was able to significantly reduce bad breath for up to 2 h. Chlorhexidine reduced bad breath only at the end of the second hour, an effect that lasted for 3 h. Conclusions: Mechanical tongue cleaning was able to immediately reduce bad breath for a short period, whereas chlorhexidine and mechanical oral hygiene reduced bad breath for longer periods, achieving the best results against morning breath.

  17. The Differential Hormonal Milieu of Morning versus Evening May Have an Impact on Muscle Hypertrophic Potential

    Science.gov (United States)

    Allen, Jeremy; Grosset, Jean-Francois

    2016-01-01

    Substantial gains in muscle strength and hypertrophy are clearly associated with the routine performance of resistance training. What is less evident is the optimal timing of the resistance training stimulus to elicit these significant functional and structural skeletal muscle changes. Therefore, this investigation determined the impact of a single bout of resistance training performed either in the morning or evening upon acute anabolic signalling (insulin-like growth factor-binding protein-3 (IGFBP-3), myogenic index and differentiation) and catabolic processes (cortisol). Twenty-four male participants (age 21.4±1.9yrs, mass 83.7±13.7kg) with no sustained resistance training experience were allocated to a resistance exercise group (REP). Sixteen of the 24 participants were randomly selected to perform an additional non-exercising control group (CP) protocol. REP performed two bouts of resistance exercise (80% 1RM) in the morning (AM: 0800 hrs) and evening (PM: 1800 hrs), with the sessions separated by a minimum of 72 hours. Venous blood was collected immediately prior to, and 5 min after, each resistance exercise and control sessions. Serum cortisol and IGFBP-3 levels, myogenic index, myotube width, were determined at each sampling period. All data are reported as mean ± SEM, statistical significance was set at P≤0.05. As expected a significant reduction in evening cortisol concentration was observed at pre (AM: 98.4±10.5, PM: 49.8±4.4 ng/ml, P0.05). Timing of resistance training regimen in the evening appears to augment some markers of hypertrophic potential, with elevated IGFBP-3, suppressed cortisol and a superior cellular environment. Further investigation, to further elucidate the time course of peak anabolic signalling in morning vs evening training conditions, are timely. PMID:27583459

  18. The effect of morning exercise on mental health of female police employees

    Directory of Open Access Journals (Sweden)

    Hassani Mohammad

    2015-06-01

    Full Text Available       Background & Aims of the Study: According to the report of world health, organization mental disorder is one of the important causes of disability in the world and it can result in decrease in the success and advancement of employees. Thus, the purpose of this research is evaluation and comparison of mental health status and its related factors in female employees who take part in morning exercise and who are exempt in one of the police units. This is a descriptive-analytic and cross sectional study. Materials & Methods: The population of this research included 85 female employees who took part in morning exercise as one group and the other group included 65 inactive people who were ill and exempt from exercise. The measurement tool in the research was the Goldberg and Hiller questionnaire of mental health that was consisted of 28 questions. Various studies in the world and in Iran suggest the high validity and reliability of the GHQ-28 questionnaire. The validity of the questionnaire has been approved in more than 70 countries and its reliability has been estimated to be between 82% and 92% in different researches and in different social groups. The data were analyzed using the descriptive statistics (frequency, mean and standard of deviation and deduction statistics (independent t-test in SPSS 16 software. Results: Analysis of the research hypotheses at significant level (p<0.05 showed that morning exercise had significant effect on mental health and its subscales such as physical complaint, anxiety, social dysfunction and depression in employees. Moreover, a significant difference was observed by comparing the active and inactive groups in relation to mental health and its subscales. Conclusions: The results of the research show that the effect of exercise and physical activities on mental health can't be denied. According to the researches that have been done, exercise is effective in two aspects of physical and mental.       

  19. Saturday-morning television: do sponsors promote high-risk behavior for burn injury?

    Science.gov (United States)

    Palmieri, Tina L; Aoki, Traci; Combs, Elena; Curri, Terese; Garma, Sylvia; Kaulkin, Cammie; Lawless, Mary Beth; Nelson, Kate; Sanders, Johanna; Warden, Nancy; Greenhalgh, David G

    2004-01-01

    Television has become an important tool for learning and socialization in children. Although television violence has been associated with adverse effects, data on depiction of fire and burn injury are lacking. We sought to determine whether Saturday-morning television programming, viewed primarily by children, depicts fire and burn injury as safe or without consequence, thus potentially increasing the incidence of burn injury in children. This was a prospective observational study. Saturday-morning children's television programs were videotaped from 7 AM to 11 AM for eight different television networks during a 6-month period. Tapes were scored for scenes depicting fire or smoke by independent observers. Recorded items included show category, scene type, gender target, context of fire, and outcome after exposure to flame. Fire events were documented during programs and their associated commercials. A total of 108 hours of children's programs, 16 hours per network, were recorded. Scenes depicting fire or smoke were identified 1960 times, with 39% of events occurring during the program itself and 61% in commercials. Fire was depicted as either safe or without consequence in 64% of incidents. Action adventure stories accounted for 56% of flame depictions. Overall, one incident involving flame and fire was portrayed for each 3 minutes of television programming. Saturday-morning television programming frequently depicts fire as safe, empowering, or exciting. The incidence of flame use in programming varies between stations but is most prevalent in action/adventure stories. Television commercials, although brief, provide the majority of the misinformation regarding fire. Medical professional societies should alert the public to this potential hazard and recommend responsible portrayal of fire in children's television programming.

  20. Target organ damage in primary hypertensive patients: role of the morning heart rate surge.

    Science.gov (United States)

    Zhan, Yuliang; Kang, Ting; Wei, Yunfeng

    The morning heart rate surge (MHRS) and morning blood pressure surge (MBPS) may be responsible for the high prevalence of cardiovascular events during the morning period. The clinical significance of the MBPS has been well established, but that of the MHRS remains unclear. Thus, we evaluated the association between the MHRS and target organ damage (TOD). A cross-sectional study of 580 hypertensive patients was performed. MHRS and heart rate variability (HRV) were analyzed by 24 h electrocardiogram. TOD was assessed by estimated glomerular filtration rate, carotid intima-media thickness (IMT), and left ventricular mass index. The prevalence of TOD tended to decrease with sleep-trough MHRS (first to fourth quartiles: 71%, 70.3%, 58.6%, and 52.7%, respectively) or prewaking MHRS quartiles (first to fourth quartiles: 65.3%, 73.6%, 61.4%, and 54.2%, respectively), whereas the opposite trend was observed for standard deviation of all normal NN intervals (SDNN). Moreover, sleep-trough MHRS, prewaking MHRS, SDNN, and SDNN index were significantly lower in patients with TOD than in those without TOD. According to four logistic regression models, the associations of prewaking MHRS, SDNN, and SDNN index with TOD were lost after adjustment for age and BP. Patients in the first (≤11.125 bpm) and second sleep-trough MHRS quartiles (11.125-15.75 bpm) had a 1.95-2.06-fold increased risk of TOD compared with those in the fourth quartile (p < 0.05). A blunted sleep-trough MHRS, which may serve as a surrogate marker for autonomic imbalance, was independently associated with TOD in primary hypertensive patients.

  1. Quantity and quality of nocturnal sleep affect morning glucose measurement in acutely burned children.

    Science.gov (United States)

    Mayes, Theresa; Gottschlich, Michele M; Khoury, Jane; Simakajornboon, Narong; Kagan, Richard J

    2013-01-01

    Hyperglycemia after severe burn injury has long been recognized, whereas sleep deprivation after burns is a more recent finding. The postburn metabolic effects of poor sleep are not clear despite reports in other populations demonstrating the association between sleep insufficiency and deleterious endocrine consequences. The aim of this study was to determine whether a relationship between sleep and glucose dynamics exists in acutely burned children. Two overnight polysomnography runs (2200 to 0600) per subject were conducted in 40 patients with a mean (± SEM) age of 9.4 ± 0.7 years, 50.1 ± 2.9% TBSA burn, and 43.2 ± 3.6% full-thickness injury. Serum glucose was drawn in the morning (0600) immediately after the sleep test. Insulin requirements during the 24-hour period preceding the 0600 glucose measurement were recorded. Generalized linear models were used by the authors to evaluate percent time in each stage of sleep, percent wake time, total sleep time, sleep efficiency, and morning serum glucose, accounting for insulin use. Increased time awake (P = .04, linear; P = .02, quadratic) and reduced time spent in stage 1 sleep (P = .03, linear) were associated with higher glucose levels. Sleep efficiency (P = .01, linear; P = .02, quadratic) and total sleep time (P = .01 linear; P = .02, quadratic) were inversely associated with glucose level. Morning glucose levels appear to be affected by the quality and quantity of overnight sleep in children who have sustained extensive burn injuries. Future research is needed to elucidate the metabolic and neuroendocrine consequences of sleep deprivation on metabolism after burns.

  2. Brightness and color variation for evening and morning twilights at Bahria of Egypt IV

    Directory of Open Access Journals (Sweden)

    A.H. Hassan

    2014-06-01

    Full Text Available Photoelectric observations of twilight (evening and morning Bahria (φ = 28° 42.94′ N, λ = 28° 59.99′ E in Egypt were done in the period between 1983 and 1985. A semiautomatic photoelectric scanner equipped with a refractor of diameter D = 10 cm and focal length f = 24 cm was used. The phenomena were followed in altitude and azimuth each 10°. For evening twilight, we find a minimum value in the color index (CI curves at Do = 12.5°. The color index (CI is found to be in the range between −1.5 and 3. A decrease on both sides of the CI toward large and small depressions is seen indicating a red background. This red color decreases on both sides of the maximum although being positive. No change of the maximum values is noticed with the azimuth. The (B–R curves show positive maximum values at 11° ⩽ Do ⩽ 13° with a decrease on both sides. Color indices are studied for the three bands (B–V, (B–R and (V–R for morning and evening twilights. For morning twilight, the (B–V color index curves show minimum (CI values with positive (B–V at Do around 8°. This can denote a dominating yellow color of the sky till Do ≈ 8–10°, where the sky is as bright in the yellow as in the blue. Stability is reached at Do = 12–14°. We believe that, the dawn shows itself at Do ⩽ 15°, while the nightfall shows itself at Do ⩽ 18°.

  3. Phylogenetic and chemotypic diversity of Periglandula species in eight new morning glory hosts (Convolvulaceae).

    Science.gov (United States)

    Beaulieu, Wesley T; Panaccione, Daniel G; Ryan, Katy L; Kaonongbua, Wittaya; Clay, Keith

    2015-01-01

    Periglandula ipomoeae and P. turbinae (Ascomycota, Clavicipitaceae) are recently described fungi that form symbiotic associations with the morning glories (Convolvulaceae) Ipomoea asarifolia and Turbina corymbosa, respectively. These Periglandula species are vertically transmitted and produce bioactive ergot alkaloids in seeds of infected plants and ephemeral mycelia on the adaxial surface of young leaves. Whether other morning glories that contain ergot alkaloids also are infected by Periglandula fungi is a central question. Here we report on a survey of eight species of Convolvulaceae (Argyreia nervosa, I. amnicola, I. argillicola, I. gracilis, I. hildebrandtii, I. leptophylla, I. muelleri, I. pes-caprae) for ergot alkaloids in seeds and associated clavicipitaceous fungi potentially responsible for their production. All host species contained ergot alkaloids in four distinct chemotypes with concentrations of 15.8-3223.0 μg/g. Each chemotype was a combination of four or five ergot alkaloids out of seven alkaloids detected across all hosts. In addition, each host species exhibited characteristic epiphytic mycelia on adaxial surfaces of young leaves with considerable interspecific differences in mycelial density. We sequenced three loci from fungi infecting each host: the nuclear rDNA internal transcribed spacer region (ITS), introns of the translation factor 1-α gene (tefA) and the dimethylallyl-tryptophan synthase gene (dmaW), which codes for the enzyme that catalyzes the first step in ergot alkaloid biosynthesis. Phylogenetic analyses confirmed that these fungi are in the family Clavicipitaceae and form a monophyletic group with the two described Periglandula species. This study is the first to report Periglandula spp. from Asian, Australian, African and North American species of Convolvulaceae, including host species with a shrub growth form and host species occurring outside of the tropics. This study demonstrates that ergot alkaloids in morning glories

  4. Nine out of 10 food advertisements shown during Saturday morning children's television programming are for foods high in fat, sodium, or added sugars, or low in nutrients.

    Science.gov (United States)

    Batada, Ameena; Seitz, Maia Dock; Wootan, Margo G; Story, Mary

    2008-04-01

    A 2005 review by the Institute of Medicine of the National Academies concluded that food marketing influences children's food preferences, consumption, and health. Given the powerful influence of marketing on children's diets, this cross-sectional study examined the types of foods, the nutritional quality of those foods, and the marketing techniques and messages used in food advertising during Saturday morning children's television programming. During 27.5 hours of programming in May 2005, 49% of advertisements shown were for food (281 food advertisements out of 572 total advertisements). The most commonly advertised food categories were ready-to-eat breakfast cereal and cereal bars (27% of all food advertisements), restaurants (19% of food advertisements), and snack foods (18% of food advertisements). Ninety-one percent of food advertisements were for foods or beverages high in fat, sodium, or added sugars or were low in nutrients. Cartoon characters were used in 74% of food advertisements, and toy or other giveaways were used in 26% of food advertisements. About half of food advertisements contained health/nutrition or physical activity messages and 86% of food advertisements contained emotional appeals. This study provides food and nutrition professionals with information about the amount and types of food children are encouraged to eat during Saturday morning television programming. The findings can help food and nutrition professionals counsel children about healthful eating and/or develop programs or policies to balance those advertisements with healthful eating messages.

  5. A Comparative Feminist Study of The Color Purple and Good Morning, Miss

    Institute of Scientific and Technical Information of China (English)

    王敏; 井媛

    2012-01-01

      Chi Li and Alice Walker are both feminist writers. In their Good Morning, Miss and The Color Purple, male-central⁃ism and the benighted state of women are thoroughly exposed. Sisterhood plays an important role in the awakening of women in both books, but the prospect of man-woman relationship is sharply different. By making comparison and analyzing the underly⁃ing reasons, it can be seen that there’s still a distance between the Western and Chinese feminism.

  6. Reading Haikuography as Racial Representation in Sonia Sanchez’s Morning Haiku

    Directory of Open Access Journals (Sweden)

    Sally Michael Hanna

    2015-02-01

    Full Text Available This study explores the role of haiku in the production of readerly and/or writerly text and in the creation of images that represent some form of “vortex” in Morning Haiku, a 2010 volume written by the African American renowned author Sonia Sanchez. Haiku in this context is adopted as a transformational poetic platform of self discovery that draws upon African American blues and jazz motifs. I would like to argue that the volume is an attempt at feminist racial representation leading to the reclamation of black/ female history or “herstory.”   Key words: Haiku, writerly text, history, herstory, blackness

  7. Effect of morning school schedule on sleep and anthropometric variables in adolescents: a follow-up study.

    Science.gov (United States)

    Brandalize, Michelle; Pereira, Rico Felden; Leite, Neiva; Filho, Geraldo Lorenzi; Louzada, Fernando Mazzilli

    2011-11-01

    The aim of this study was to assess whether the shift from afternoon to morning classes reduces the duration of sleep and whether this reduction has any relation to body fat measurements. This is a follow-up study in which students (n = 379), 12.4 (SD(+/-)0.7) yrs old, were evaluated before and after the school schedule shift, with a 1-yr interval between the first and second data collections. Adolescents were divided into two groups: an afternoon-morning group (students who shifted from afternoon to morning classes) and an afternoon-afternoon group (students who remained in afternoon classes). The morning schedule of classes lasted from 07:30 and 12:00?h, and the afternoon schedule of classes lasted from 13:00 and 17:30?h. Self-reported bedtime, wake-up time, and time-in-bed were obtained. Body mass index, waist circumference, and body fat percentage were obtained by direct measures. The results showed a reduction of time-in-bed during weekdays for those students who changed to the morning session (p < .001). Analysis of covariance (ANCOVA) for repeated measures of anthropometric differences between afternoon-afternoon and afternoon-morning groups showed no effect of the school schedule change on weight gain. In conclusion, the time-in-bed reduction in the period analyzed cannot be considered to be a mediating factor to modifications in overweight anthropometric indicators.

  8. Can breakfast tryptophan and vitamin B6 intake and morning exposure to sunlight promote morning-typology in young children aged 2 to 6 years?

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    Nakade Miyo

    2012-05-01

    Full Text Available Abstract This study tried to examine, from epidemiological and physiologic anthropological (Japanese culture on breakfast points of view, the integrated effects of the amount of tryptophan and vitamin B6 intake and the following exposure to sunlight on the circadian typology and sleep habits in young Japanese children aged 2 to 6 years, using the newly-evaluated calculating system of tryptophan (Tryptophan Index 2009 and vitamin B6 intake (VitaminB6 Index 2009 at breakfast. The positive and significant correlation was shown between the Morningness-Eveningness (M-E score and the Tryptophan Index and also the Vitamin B6 Index. This positive correlation between M-E score and amount of tryptophan intake was shown only by children who were exposed to sunlight for longer than 10min after breakfast. These results might support the following hypothesis: higher tryptophan and vitamin B6 intake at breakfast could promote the synthesis of serotonin via light stimulation in the morning in children.

  9. Can breakfast tryptophan and vitamin B6 intake and morning exposure to sunlight promote morning-typology in young children aged 2 to 6 years?

    Science.gov (United States)

    2012-01-01

    This study tried to examine, from epidemiological and physiologic anthropological (Japanese culture on breakfast) points of view, the integrated effects of the amount of tryptophan and vitamin B6 intake and the following exposure to sunlight on the circadian typology and sleep habits in young Japanese children aged 2 to 6 years, using the newly-evaluated calculating system of tryptophan (Tryptophan Index 2009) and vitamin B6 intake (VitaminB6 Index 2009) at breakfast. The positive and significant correlation was shown between the Morningness-Eveningness (M-E) score and the Tryptophan Index and also the Vitamin B6 Index. This positive correlation between M-E score and amount of tryptophan intake was shown only by children who were exposed to sunlight for longer than 10min after breakfast. These results might support the following hypothesis: higher tryptophan and vitamin B6 intake at breakfast could promote the synthesis of serotonin via light stimulation in the morning in children. PMID:22738346

  10. A New Baroreceptor Sensitivity-Restoring Ca-Channel Blocker Diminishes Age-Related Morning Blood Pressure Increase in Hypertensive Patients: Open-Label Monitoring of Azelnidipine Treatment for Hypertension in the Early Morning (At-HOME Study

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    Mitsunori Sugiyama

    2010-01-01

    Full Text Available Background: Morning blood pressure (BP surge, which exhibits an age-related increase, is a risk factor for stroke in elderly hypertensive patients, independently of the 24-h BP level. We studied the effect of the new baroreceptor sensitivity (BRS-restoring Ca-channel blocker (CCB azelnidipine (AZ on this age-related morning BP increase. Methods: We conducted a 16-week prospective study to clarify the effect of morning dosing of AZ on home BPs measured in the morning and in the evening in 2,546 hypertensive patients (mean age, 65.1 years; female, 53.6%. Results: At baseline, ME-Dif (morning systolic BP [SBP]–evening SBP increased with age, independently of ME-Ave (average of the morning and evening SBPs. This age-related increase of ME-Dif was exaggerated by regular alcohol drinking and beta-blocker use. After AZ treatment (14.3 ± 3.6 mg/day, ME-AV and ME-Dif were significantly reduced independently of each other, with reductions of –18.1 ± 15.6 and –2.5 ± 13.2 mmHg, respectively (both p < 0.001. AZ treatment decreased age-related increase in ME-Dif particularly in patients who were regular consumers of alcohol and in beta-blocker users. Conclusions: The new BRS-restoring CCB AZ significantly reduced age-related increase in morning BP and had some potential benefit on cardiovascular protection in hypertension, particularly in elderly patients and/or consumers of alcohol.

  11. Evaluation of behavioral states among morning and evening active healthy individuals

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    M.P. Hidalgo

    2002-07-01

    Full Text Available The Horne-Östberg questionnaire partly covers some factors that may be important determinants of peak time and characterize patterns of behavior. We conducted a study for the evaluation of self-reported behavioral states (hunger sensation, availability for study, physical exercise, solving daily problems, and time preferences as expressions of underlying cyclic activity. Three hundred and eighteen community subjects without history of medical, psychiatric, or sleep disorders were evaluated in a cross-sectional design. A self-report about daily highest level of activity was used to categorize individuals into morning, evening, and indifferently active. Time-related behavioral states were evaluated with 23 visual analog questions. The responses to most analogic questions were significantly different between morning and evening active subjects. Logistic regression analysis identified a group of behaviors more strongly associated with the self-reported activity pattern (common wake up time, highest subjective fatigue, as well as wake up, bedtime, exercise and study preferences. These findings suggested that the patterns of activity presented by normal adults were related to specific common behavioral characteristics that may contribute to peak time.

  12. Quantitative evaluation of regular morning meetings aimed at improving work practices associated with effective interdisciplinary communication.

    Science.gov (United States)

    Aston, Judy; Shi, Edward; Bullôt, Helen; Galway, Robyn; Crisp, Jackie

    2006-04-01

    In 2000, an interdisciplinary surgical morning meeting (SMM) was introduced into the infants' and toddlers' ward of a major paediatric hospital to help overcome a number of communication and work process problems among the health professionals providing care to children/families. The objective of this study was to evaluate the impact of the SMM on a range of work practices. Comparative design including pre- and postintervention data collection was used. Data were collected on 100 patient records. Twenty children, from each of the five diagnostic-related groups most commonly admitted to the ward, were included. Demographic, medical review, documentation, critical incidents and complaint variables were obtained from three sources: the hospital clinical information system, the children's medical records and the hospital reporting systems for complaints and critical incidents. Children in the postintervention group were significantly more likely to be reviewed regularly by medical staff, to be reviewed in the morning, to have plans for discharge documented regularly throughout their admission and to have admission summary sheets completed at the time of discharge. The findings of the quantitative evaluation add some weight to the arguments for the purposely structured introduction of interdisciplinary teams into acute-care environments.

  13. Traditional Tongan cures for morning sickness and their mutagenic/toxicological evaluations.

    Science.gov (United States)

    Ostraff, M; Anitoni, K; Nicholson, A; Booth, G M

    2000-07-01

    Every year millions of women become pregnant, and more than 60% of them will develop some form of morning sickness. Yet drugs like Thalidomide, Bendectin and other possibly potent teratogens administered for pre-partum nausea have severely limited any medicinal intervention. In Tonga, women have been treated for morning sickness for hundreds of years. Two types of traditional treatments exist, the first one consists of an infusion of fresh leaves, commonly called vai momoko. The second type of treatment is called vai haka, which is made from the boiled bark of several trees. In this paper we describe the results of 6 months of intensive interviews in Tonga regarding the second type of treatment called vai haka. In addition, we tested vai haka for mutagenic and teratogenic effects. Data from the Ames TA-98 mutagenic bioassay clearly indicate that vai haka is not mutagenic with or without S-9 activation. Twenty-six experimental CD-1 white mice were gavaged with 0.1 ml of vai haka (at 540xthe human dose) while the control group of 17 mice were gavaged with 0.1 ml of water to determine teratogenic and developmental effects of the vai haka. No significant teratogenic or developmental anomalies occurred in the mice dosed with vai haka compared to the controls.

  14. Evening and morning alterations in Obstructive Sleep Apnea red blood cell proteome

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    Amélia Feliciano

    2017-04-01

    Full Text Available This article presents proteomics data referenced in [1] Using proteomics-based evaluation of red blood cells (RBCs, we have identified differentially abundant proteins associated with Obstructive Sleep Apnea Syndrome (OSA. RBCs were collected from peripheral blood of patients with moderate/severe OSA or snoring at pre- (evening and post-night (morning polysomnography, so that proteome variations between these time points could be assessed. RBC cytoplasmic fraction depleted of hemoglobin, using Hemovoid™ system, were analyzed by two-dimensional fluorescence difference gel electrophoresis (2D-DIGE, the 2D image software-based analyzed and relevant differentially abundant proteins identified by mass spectrometry (MS. MS identified 31 protein spots differentially abundant corresponding to 21 unique proteins possibly due to the existence of post-translational modification regulations. Functional analysis by bioinformatics tools indicated that most proteins are associated with catalytic, oxidoreductase, peroxidase, hydrolase, ATPase and anti-oxidant activity. At morning a larger numbers of differential proteins including response to chemical stimulus, oxidation reduction, regulation of catalytic activity and response to stress were observed in OSA. The data might support further research in OSA biomarker discovery and validation.

  15. Sudden early-morning awakening impairs immediate tactical planning in a changing 'emergency' scenario.

    Science.gov (United States)

    Horne, Jim; Moseley, Robert

    2011-06-01

    This was a realistic military-type exercise assessing unexpected, abrupt early-morning awakening effects on immediate 'executive function' and the ability to comprehend and deal with a sudden emergency under a changing situation. Twenty (average age 21years) healthy, highly motivated junior officer reservists were assigned randomly to two equal, independent groups, unforewarned as to what would happen. The experimental group was woken abruptly at 03:00h (plan of engagement with minimal loss of resources, to be completed within 15min. A control group slept until 07:30h; they were then presented with the identical emergency 1h later. Participants worked individually, under time pressure, receiving written information, map and other details, all containing relevant, irrelevant and misleading information. Halfway through, they were given (unexpectedly) a critical update necessitating a change of tactics. Performance was scored blind by instructors, under five categories. Eight of the experimental group versus three controls failed overall, with significant group differences on three specific categories relying on flexible decision-making: 'identification of available cover', 'use of available assets' and 'extraction of relevant from irrelevant information'. Other, logical and highly trained skills were unimpaired. Ours was a 'worst case scenario', combining short sleep, circadian 'trough' and sleep inertia, all of which differentiated the two groups, unlike typical laboratory studies. Nevertheless, it was relevant to real-life situations involving highly motivated, trained individuals making critical innovative decisions in the early morning versus the normal waking day. © 2010 European Sleep Research Society.

  16. LWD–TCP complex activates the morning gene CCA1 in Arabidopsis

    Science.gov (United States)

    Wu, Jing-Fen; Tsai, Huang-Lung; Joanito, Ignasius; Wu, Yi-Chen; Chang, Chin-Wen; Li, Yi-Hang; Wang, Ying; Hong, Jong Chan; Chu, Jhih-Wei; Hsu, Chao-Ping; Wu, Shu-Hsing

    2016-01-01

    A double-negative feedback loop formed by the morning genes CIRCADIAN CLOCK ASSOCIATED1 (CCA1)/LATE ELONGATED HYPOCOTYL (LHY) and the evening gene TIMING OF CAB EXPRESSION1 (TOC1) contributes to regulation of the circadian clock in Arabidopsis. A 24-h circadian cycle starts with the peak expression of CCA1 at dawn. Although CCA1 is targeted by multiple transcriptional repressors, including PSEUDO-RESPONSE REGULATOR9 (PRR9), PRR7, PRR5 and CCA1 HIKING EXPEDITION (CHE), activators of CCA1 remain elusive. Here we use mathematical modelling to infer a co-activator role for LIGHT-REGULATED WD1 (LWD1) in CCA1 expression. We show that the TEOSINTE BRANCHED 1-CYCLOIDEA-PCF20 (TCP20) and TCP22 proteins act as LWD-interacting transcriptional activators. The concomitant binding of LWD1 and TCP20/TCP22 to the TCP-binding site in the CCA1 promoter activates CCA1. Our study reveals activators of the morning gene CCA1 and provides an action mechanism that ensures elevated expression of CCA1 at dawn to sustain a robust clock. PMID:27734958

  17. Morning melatonin ingestion and diurnal variation of short-term maximal performances in soccer players.

    Science.gov (United States)

    Ghattassi, K; Hammouda, O; Graja, A; Boudhina, N; Chtourou, H; Hadhri, S; Driss, T; Souissi, N

    2016-03-01

    Aim Very few studies have investigated the temporal specificity of melatonin (MEL) ingestion upon short-term maximal athletic performances. The aim of the present study was to explore the effect of morning MEL ingestion on cognitive and physical performances measured in the afternoon. Methods Twelve soccer players from a Tunisian squad (17.9 ± 1.3 years, 1.74 ± 0.06 m and 62.0 ± 8.8 kg) participated in the present study. They performed two testing sessions at 08:00 h, 12:00 h and 16:00 h after either MEL (5mg) or placebo (PLA) ingestion, in a randomized order. During each period, the participants performed the following cognitive and physical tests: reaction time and vigilance tests, medicine-ball throw (MBT), five jumps, handgrip strength (HG), and agility tests. Results cognitive and physical performances were significantly higher at 16:00 h compared to 08:00 h during the two conditions (p ingestion did not affect physical and cognitive performances measured at 12:00 h and 16:00 h. Conclusion morning MEL ingestion has no unfavourable effect on afternoon physical and cognitive performances in soccer players.

  18. Morning ambush attacks by black-footed ferrets on emerging prairie dogs

    Science.gov (United States)

    Eads, D.A.; Biggins, D.E.; Jachowski, D.S.; Livieri, T.M.; Millspaugh, J.J.; Forsberg, M.

    2010-01-01

    Black-footed ferrets (Mustela nigripes) often hunt at night, attacking normally diurnal prairie dogs (Cynomys spp.) in underground burrow systems. While monitoring black-footed ferrets in South Dakota during morning daylight hours, we observed an adult female ferret ambush a black-tailed prairie dog (C. ludovicianus) emerging from a burrow. On a neighboring colony, we observed a second adult female ferret engaging in similar ambush behaviors on 12 occasions, although prey was not visible. We retrospectively assessed radio-telemetry data on white-tailed prairie dogs (C. leucurus) and a male and a female ferret to evaluate ferret activity in relation to timing of prairie dog emergence. Activity of radio-collared ferrets was high during the hourly period when prairie dogs first emerged and the following 2 hr, relative to later daylight hours. Such behavior is consistent with behaviors observed in South Dakota. Nighttime movements by ferrets might involve hunting but also reconnaissance of prey preparatory to morning ambush attacks.

  19. The Diurnal Temperature Cycle and Its Relation to Boundary-Layer Structure During the Morning Transition

    Science.gov (United States)

    Ketzler, G.

    2014-05-01

    The morning portion of the near-surface diurnal temperature cycle is analyzed in combination with heat-flux and vertical temperature-gradient data. During summer, mean diurnal cycles of temperature rates-of-change show periods that can be related to defined points of the morning transition (MT). The start of the MT is clearly marked with a temperature discontinuity, apparent even on individual days, while the end of the transition is apparent only when using averages over many days. The findings concerning the timing of the MT using temperature cycle analysis correspond well with studies using heat-flux measurements. Mean diurnal cycles of temperature rates-of-change for stations in different urban and valley positions show differences that can partly be explained by apparent effects of the surroundings. For the valley situation, the timing differences and their relation to station position in the valley are generally plausible, while urban effects on the diurnal cycle are apparent but less distinct, which may be due to the small number of stations used. The results indicate that warming already begins before heat-flux crossover, which is the current definition of the beginning of the MT. This definition should be extended to include the phase between the temperature rate-of-change crossover and heat-flux crossover, which represents the early part of the MT before warming reaches instrument level.

  20. Relevance of Morning and Evening Energy and Macronutrient Intake during Childhood for Body Composition in Early Adolescence

    Directory of Open Access Journals (Sweden)

    Tanja Diederichs

    2016-11-01

    Full Text Available (1 Background: This study investigated the relevance of morning and evening energy and macronutrient intake during childhood for body composition in early adolescence; (2 Methods: Analyses were based on data from 372 DONALD (DOrtmund Nutritional and Anthropometric Longitudinally Designed study participants. Explorative life-course plots were performed to examine whether morning or evening energy and macronutrient intake at 3/4 years, 5/6 years, or 7/8 years is critical for fat mass index (FMI [kg/m2] and fat free mass index (FFMI [kg/m2] in early adolescence (10/11 years. Subsequently, exposures in periods identified as consistently critical were examined in depth using adjusted regression models; (3 Results: Life-course plots identified morning fat and carbohydrate (CHO intake at 3/4 years and 7/8 years as well as changes in these intakes between 3/4 years and 7/8 years as potentially critical for FMI at 10/11 years. Adjusted regression models corroborated higher FMI values at 10/11 years among those who had consumed less fat (p = 0.01 and more CHO (p = 0.01 in the morning at 7/8 years as well as among those who had decreased their morning fat intake (p = 0.02 and increased their morning CHO intake (p = 0.05 between 3/4 years and 7/8 years; (4 Conclusion: During childhood, adherence to a low fat, high CHO intake in the morning may have unfavorable consequences for FMI in early adolescence.

  1. Effects of Acute Endurance Exercise Performed in the Morning and Evening on Inflammatory Cytokine and Metabolic Hormone Responses.

    Directory of Open Access Journals (Sweden)

    Hyeon-Ki Kim

    Full Text Available To compare the effects of endurance exercise performed in the morning and evening on inflammatory cytokine responses in young men.Fourteen healthy male participants aged 24.3 ± 0.8 years (mean ± standard error performed endurance exercise in the morning (0900-1000 h on one day and then in the evening (1700-1800 h on another day with an interval of at least 1 week between each trial. In both the morning and evening trials, the participants walked for 60 minutes at approximately 60% of the maximal oxygen uptake (VO2max on a treadmill. Blood samples were collected to determine hormones and inflammatory cytokines at pre-exercise, immediately post exercise, and 2 h post exercise.Plasma interleukin (IL-6 and adrenaline concentrations were significantly higher immediately after exercise in the evening trial than in the morning trial (P < 0.01, both. Serum free fatty acids concentrations were significantly higher in the evening trial than in the morning trial at 2 h after exercise (P < 0.05. Furthermore, a significant correlation was observed between the levels of IL-6 immediately post-exercise and free fatty acids 2 h post-exercise in the evening (r = 0.68, P < 0.01.These findings suggest that the effect of acute endurance exercise in the evening enhances the plasma IL-6 and adrenaline concentrations compared to that in the morning. In addition, IL-6 was involved in increasing free fatty acids, suggesting that the evening is more effective for exercise-induced lipolysis compared with the morning.

  2. Online self-expression and experimentation as 'reflectivism': Using text analytics to examine the participatory forum Hello Sunday Morning.

    Science.gov (United States)

    Carah, Nicholas; Meurk, Carla; Angus, Daniel

    2017-03-01

    Hello Sunday Morning is an online health promotion organisation that began in 2009. Hello Sunday Morning asks participants to stop consuming alcohol for a period of time, set a goal and document their progress on a personal blog. Hello Sunday Morning is a unique health intervention for three interrelated reasons: (1) it was generated outside a clinical setting, (2) it uses new media technologies to create structured forms of participation in an iterative and open-ended way and (3) participants generate a written record of their progress along with demographic, behavioural and engagement data. This article presents a text analysis of the blog posts of Hello Sunday Morning participants using the software program Leximancer. Analysis of blogs illustrates how participants' expressions change over time. In the first month, participants tended to set goals, describe their current drinking practices in individual and cultural terms, express hopes and anxieties and report on early efforts to change. After month 1, participants continued to report on efforts to change and associated challenges and reflect on their place as individuals in a drinking culture. In addition to this, participants evaluated their efforts to change and presented their 'findings' and 'theorised' them to provide advice for others. We contextualise this text analysis with respect to Hello Sunday Morning's development of more structured forms of online participation. We offer a critical appraisal of the value of text analytics in the development of online health interventions.

  3. Light activates output from evening neurons and inhibits output from morning neurons in the Drosophila circadian clock.

    Directory of Open Access Journals (Sweden)

    Marie Picot

    2007-11-01

    Full Text Available Animal circadian clocks are based on multiple oscillators whose interactions allow the daily control of complex behaviors. The Drosophila brain contains a circadian clock that controls rest-activity rhythms and relies upon different groups of PERIOD (PER-expressing neurons. Two distinct oscillators have been functionally characterized under light-dark cycles. Lateral neurons (LNs that express the pigment-dispersing factor (PDF drive morning activity, whereas PDF-negative LNs are required for the evening activity. In constant darkness, several lines of evidence indicate that the LN morning oscillator (LN-MO drives the activity rhythms, whereas the LN evening oscillator (LN-EO does not. Since mutants devoid of functional CRYPTOCHROME (CRY, as opposed to wild-type flies, are rhythmic in constant light, we analyzed transgenic flies expressing PER or CRY in the LN-MO or LN-EO. We show that, under constant light conditions and reduced CRY function, the LN evening oscillator drives robust activity rhythms, whereas the LN morning oscillator does not. Remarkably, light acts by inhibiting the LN-MO behavioral output and activating the LN-EO behavioral output. Finally, we show that PDF signaling is not required for robust activity rhythms in constant light as opposed to its requirement in constant darkness, further supporting the minor contribution of the morning cells to the behavior in the presence of light. We therefore propose that day-night cycles alternatively activate behavioral outputs of the Drosophila evening and morning lateral neurons.

  4. Does raising morning rectal temperature to evening levels offset the diurnal variation in muscle force production?

    Science.gov (United States)

    Edwards, Ben J; Pullinger, Samuel A; Kerry, Jonathan W; Robinson, William R; Reilly, Tom P; Robertson, Colin M; Waterhouse, James M

    2013-05-01

    Muscle force production and power output in active males, regardless of the site of measurement (hand, leg, or back), are higher in the evening than in the morning. This diurnal variation is attributed to motivational, peripheral and central factors, and higher core and, possibly, muscle temperatures in the evening. This study investigated whether increasing morning rectal temperatures to evening resting values, by active or passive warm-ups, leads to muscle force production and power output becoming equal to evening values in motivated subjects. Ten healthy active males (mean ± SD: age, 21.2 ± 1.9 yrs; body mass, 75.4 ± 8 kg; height, 1.76 ± .06 m) completed the study, which was approved by the University Ethics Committee. The subjects were familiarized with the techniques and protocol and then completed four sessions (separated by at least 48 h): control morning (07:30 h) and evening (17:30 h) sessions (with an active 5-min warm-up) and then two further sessions at 07:30 h but proceeded by an extended active or passive warm-up to raise rectal temperature to evening values. These last two sessions were counterbalanced in order of administration. During each trial, three measures of handgrip strength, isokinetic leg strength measurements (of knee flexion and extension at 1.05 and 4.19 rad.s(-1) through a 90° range of motion), and four measures of maximal voluntary contraction (MVC) on an isometric ergometer (utilizing the twitch-interpolation technique) were performed. Rectal and intra-aural temperatures, ratings of perceived exertion (RPE) and thermal comfort (TC) were measured. Measurements were made after the subjects had reclined for 30 min and after the warm-ups and prior to the measurement of handgrip and isokinetic and isometric ergometry. Muscle temperature was taken after the warm-up and immediately before the isokinetic and MVC measurements. Warm-ups were either active (cycle ergometer at 150 W) or passive (resting in a room at 35 °C, relative

  5. Localized auroral disturbance in the morning sector of topside ionosphere as a standing electromagnetic wave

    Energy Technology Data Exchange (ETDEWEB)

    Dubinin, E.M.; Israelevich, P.L.; Nikolaeva, N.S.; Podgornyi, I.M.; Kutiev, I.

    1985-06-01

    The fine structure and plasma properties of an auroral disturbance observed with the Intercosmos-Bulgaria-1300 satellite are analyzed. The disturbance was detected in the morning sector of the sky at an altitude of about 850 km in December of 1981. Strong jumps (about 80 mV/m) in the electric and magnetic fields and fluctuations of ion density were detected within the disturbance. The electric and magnetic fields were characterized by a distinct spatial-temporal relationship typical for a standing quasi-monochromatic wave with a frequency of 1 Hz. The ratio of the amplitudes of electric and magnetic fluctuations was equal to the velocity of Alfven waves. The strong parallel component of the electric field (about 30 mV/m) and the large ion density of the fluctuations indicate changes in the plasma properties of the disturbance. The possibility of anomalous resistivity effects in the disturbance is also briefly considered. 23 references.

  6. Effects of air pollutants on plant cell tissue cultures. [Tobacco, rose soybean, periwinkle, and morning glory

    Energy Technology Data Exchange (ETDEWEB)

    1967-01-01

    Experiments were conducted to determine morphological and physiological effects of air pollutants on plant tissue cultures. Several cultures will be exposed to polluted atmospheres for various periods and observed for effects. The cultures which have been developed for this purpose are: tobacco pith, rose stem, soybean stem, periwinkle, and morning glory. Exposures will follow two regimens: a relatively high concentration of pollutant for a short duration and a low concentration for a long duration. Effects of pollutants on cell morphology will be observed microscopically. Effects on cell physiology may include altered respiratory quotients which will be determined by Warburg respirometry techniques. The design of an apparatus that is being developed to mix a pollutant with air and deliver it to the cultures is described.

  7. Awake at 4 AM: treatment of insomnia with early morning awakenings among older adults.

    Science.gov (United States)

    Fiorentino, Lavinia; Martin, Jennifer L

    2010-11-01

    Insomnia is a common problem among older adults. In particular, older adults experience insomnia coupled with early morning awakenings due to an interaction between age-related changes in circadian rhythm timing coupled with behavior changes that contribute to sustained poor sleep. Cognitive-behavioral therapy for insomnia (CBT-I), at times coupled with circadian interventions (e.g., timed light exposure), are likely to be most successful in optimizing sleep quality. In delivering CBT-I to older adults, modifications are sometimes necessary to accommodate for medical problems, lifestyle, social factors, and patient preferences. Addition of circadian interventions can ameliorate the negative effects of inappropriately timed sleep as well. These treatment methods can be highly effective and benefits can be long-standing. A case example is used to illustrate these points.

  8. Congestion Behavior under Uncertainty on Morning Commute with Preferred Arrival Time Interval

    Directory of Open Access Journals (Sweden)

    LingLing Xiao

    2014-01-01

    Full Text Available This paper extends the bottleneck model to study congestion behavior of morning commute with flexible work schedule. The proposed model assumes a stochastic bottleneck capacity which follows a uniform distribution and homogeneous commuters who have the same preferred arrival time interval. The commuters are fully aware of the stochastic properties of travel time and schedule delay distributions at all departure times that emerge from day-to-day capacity variations. The commuters’ departure time choice follows user equilibrium (UE principle in terms of the expected trip cost. Analytical and numerical solutions of this model are provided. The equilibrium departure time patterns are examined which show that the stochastic capacity increases the mean trip cost and lengthens the rush hour. The adoption of flexitime results in less congestion and more efficient use of bottleneck capacity than fixed-time work schedule. The longer the flexi-time interval is, the more uniformly distributed the departure times are.

  9. Matrix-mini-tablets of lornoxicam for targeting early morning peak symptoms of rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    Abdul Hadi Mohd

    2014-05-01

    Full Text Available Objective(s: The aim of present research was to develop matrix-mini-tablets of lornoxicam filled in capsule for targeting early morning peak symptoms of rheumatoid arthritis. Materials and Methods:Matrix-mini-tablets of lornoxicam were prepared by direct compression method using microsomal enzyme dependent and pH-sensitive polymers which were further filled into an empty HPMC capsule. To assess the compatibility, FT-IR and DSC studies for pure drug, polymers and their physical mixture were performed. The formulated batches were subjected to physicochemical studies, estimation of drug content, in vitro drug release, drug release kinetics, and stability studies. Results:  When FTIR and DSC studies were performed it was found that there was no interaction between lornoxicam and polymers which used. All the physicochemical properties of prepared matrix-mini-tablets were found to be in normal limits. The percentage of drug content was found to be 99.60±0.07%. Our optimized matrix mini-tablets-filled-capsule formulation F30 released lornoxicam after a lag time of 5.02±0.92 hr, 95.48±0.65 % at the end of 8 hr and 99.90±0.83 % at the end of 12 hr. Stability was also found for this formulation as per the guidelines of International Conference on Harmonisation of Technical Requirements of Pharmaceuticals for Human Use. Conclusion: A novel colon targeted delivery system of lornoxicam was successfully developed by filling matrix-mini-tablets into an empty HPMC capsule shell for targeting early morning peak symptoms of rheumatoid arthritis.

  10. Cold Exposure Can Induce an Exaggerated Early-Morning Blood Pressure Surge in Young Prehypertensives.

    Directory of Open Access Journals (Sweden)

    Cian-Hui Hong

    Full Text Available Prehypertension is related to a higher risk of cardiovascular events than normotension. Our previous study reported that cold exposure elevates the amplitude of the morning blood pressure surge (MBPS and is associated with a sympathetic increase during the final sleep transition, which might be critical for sleep-related cardiovascular events in normotensives. However, few studies have explored the effects of cold exposure on autonomic function during sleep transitions and changes of autonomic function among prehypertensives. Therefore, we conducted an experiment for testing the effects of cold exposure on changes of autonomic function during sleep and the MBPS among young prehypertensives are more exaggerate than among young normotensives. The study groups consisted of 12 normotensive and 12 prehypertensive male adults with mean ages of 23.67 ± 0.70 and 25.25 ± 0.76 years, respectively. The subjects underwent cold (16°C and warm (23°C conditions randomly. The room temperature was maintained at either 23°C or 16°C by central air conditioning and recorded by a heat-sensitive sensor placed on the forehead and extended into the air. BP was measured every 30 minutes by using an autonomic BP monitor. Electroencephalograms, electrooculograms, electromyograms, electrocardiograms, and near body temperature were recorded by miniature polysomnography. Under cold exposure, a significantly higher amplitude of MBPS than under the warm condition among normotensives; however, this change was more exaggerated in prehypertensives. Furthermore, there was a significant decrease in parasympathetic-related RR and HF during the final sleep transition and a higher early-morning surge in BP and in LF% among prehypertensives, but no such change was found in normotensives. Our study supports that cold exposure might increase the risk of sleep-related cardiovascular events in prehypertensives.

  11. Matrix-mini-tablets of lornoxicam for targeting early morning peak symptoms of rheumatoid arthritis

    Science.gov (United States)

    Mohd, Abdul Hadi; Raghavendra Rao, Nidagurthi Guggilla; Avanapu, Srinivasa Rao

    2014-01-01

    Objective(s): The aim of present research was to develop matrix-mini-tablets of lornoxicam filled in capsule for targeting early morning peak symptoms of rheumatoid arthritis. Materials and Methods: Matrix-mini-tablets of lornoxicam were prepared by direct compression method using microsomal enzyme dependent and pH-sensitive polymers which were further filled into an empty HPMC capsule. To assess the compatibility, FT-IR and DSC studies for pure drug, polymers and their physical mixture were performed. The formulated batches were subjected to physicochemical studies, estimation of drug content, in vitro drug release, drug release kinetics, and stability studies. Results: When FTIR and DSC studies were performed it was found that there was no interaction between lornoxicam and polymers which used. All the physicochemical properties of prepared matrix-mini-tablets were found to be in normal limits. The percentage of drug content was found to be 99.60±0.07%. Our optimized matrix mini-tablets-filled-capsule formulation F30 released lornoxicam after a lag time of 5.02±0.92 hr, 95.48±0.65 % at the end of 8 hr and 99.90±0.83 % at the end of 12 hr. Stability was also found for this formulation as per the guidelines of International Conference on Harmonisation of Technical Requirements of Pharmaceuticals for Human Use. Conclusion: A novel colon targeted delivery system of lornoxicam was successfully developed by filling matrix-mini-tablets into an empty HPMC capsule shell for targeting early morning peak symptoms of rheumatoid arthritis. PMID:24967065

  12. Morning Cortisol Levels and Cognitive Abilities in People With Type 2 Diabetes

    Science.gov (United States)

    Reynolds, Rebecca M.; Strachan, Mark W.J.; Labad, Javier; Lee, Amanda J.; Frier, Brian M.; Fowkes, F. Gerald; Mitchell, Rory; Seckl, Jonathan R.; Deary, Ian J.; Walker, Brian R.; Price, Jackie F.

    2010-01-01

    OBJECTIVE People with type 2 diabetes are at increased risk of cognitive impairment but the mechanism is uncertain. Elevated glucocorticoid levels in rodents and humans are associated with cognitive impairment. We aimed to determine whether fasting cortisol levels are associated with cognitive ability and estimated lifetime cognitive change in an elderly population with type 2 diabetes. RESEARCH DESIGN AND METHODS This was a cross-sectional study of 1,066 men and women aged 60–75 years with type 2 diabetes, living in Lothian, Scotland (the Edinburgh Type 2 Diabetes Study). Cognitive abilities in memory, nonverbal reasoning, information processing speed, executive function, and mental flexibility were tested, and a general cognitive ability factor, g, was derived. Prior intelligence was estimated from vocabulary testing, and adjustment for scores on this test was used to estimate lifetime cognitive change. Relationships between fasting morning plasma cortisol levels and cognitive ability and estimated cognitive change were tested. Models were adjusted for potential confounding and/or mediating variables including metabolic and cardiovascular variables. RESULTS In age-adjusted analyses, higher fasting cortisol levels were not associated with current g or with performance in individual cognitive domains. However, higher fasting cortisol levels were associated with greater estimated cognitive decline in g and in tests of working memory and processing speed, independent of mood, education, metabolic variables, and cardiovascular disease (P < 0.05). CONCLUSIONS High morning cortisol levels in elderly people with type 2 diabetes are associated with estimated age-related cognitive change. Strategies targeted at lowering cortisol action may be useful in ameliorating cognitive decline in individuals with type 2 diabetes. PMID:20097784

  13. Ambulatory Morning Report: A Case-Based Method of Teaching EBM Through Experiential Learning.

    Science.gov (United States)

    Luciano, Gina L; Visintainer, Paul F; Kleppel, Reva; Rothberg, Michael B

    2016-02-01

    Evidence-based medicine (EBM) skills are important to daily practice, but residents generally feel unskilled incorporating EBM into practice. The Kolb experiential learning theory, as applied to curricular planning, offers a unique methodology to help learners build an EBM skill set based on clinical experiences. We sought to blend the learner-centered, case-based merits of the morning report with an experientially based EBM curriculum. We describe and evaluate a patient-centered ambulatory morning report combining the User's Guides to the Medical Literature approach to EBM and experiential learning theory in the internal medicine department at Baystate Medical Center. The Kolb experiential learning theory postulates that experience transforms knowledge; within that premise we designed a curriculum to build EBM skills incorporating residents' patient encounters. By developing structured clinical questions based on recent clinical problems, residents activate prior knowledge. Residents acquire new knowledge through selection and evaluation of an article that addresses the structured clinical questions. Residents then apply and use new knowledge in future patient encounters. To assess the curriculum, we designed an 18-question EBM test, which addressed applied knowledge and EBM skills based on the User's Guides approach. Of the 66 residents who could participate in the curriculum, 61 (92%) completed the test. There was a modest improvement in EBM knowledge, primarily during the first year of training. Our experiential curriculum teaches EBM skills essential to clinical practice. The curriculum differs from traditional EBM curricula in that ours blends experiential learning with an EBM skill set; learners use new knowledge in real time.

  14. Communicating through caregiver singing during morning care situations in dementia care.

    Science.gov (United States)

    Hammar, Lena Marmstål; Emami, Azita; Engström, Gabriella; Götell, Eva

    2011-03-01

    It is well known that persons with dementia (PWD) have problems expressing and interpreting communication, making interaction with others difficult. Interaction between PWD and their caregivers is crucial, and several strategies have been investigated to facilitate communication during caregiving. Music therapeutic caregiving (MTC)--when caregivers sing for or together with PWD during caregiving activities--has been shown to enhance communication for PWD, evoking more vitality and positive emotions. The aim of this study was to describe how PWD and their caregivers express verbal and nonverbal communication and make eye contact during the care activity 'getting dressed', during morning care situations without and with MTC. Findings revealed that during the situations without MTC, the caregivers led the dressing procedure with verbal instructions and body movements and seldom invited the PWD to communicate or participate in getting dressed. Patterns in responses to caregivers' instructions included both active and compliant responses and reactions that were resistant and aggressive, confused, and disruptive. In contrast to the 'ordinary' morning care situation, during MTC, the caregivers seemed interested in communicating with the PWD and solicited their mutual engagement. Although verbal communication consisted of singing about things other than getting dressed, e.g. dancing, love, sailing, God, the PWD mostly responded to caregivers in a composed manner, by being active, compliant, and relaxed, though some were also resistant or incongruent. The authors conclude that MTC could be a way for PWD and their caregivers to successfully interact and co-operate during caring situations, as it seems to evoke enhanced communication for both partners in this context.

  15. Damage suffered by swamp morning glory (Ipomoea aquatica Forsk) exposed to vanadium (V).

    Science.gov (United States)

    Chen, Ting; Li, Ting-Qiang; Yang, Jin-Yan

    2016-03-01

    To elucidate the physiological and morphological responses generated by vanadium (V) in plants, hydroponic culture experiments were performed with swamp morning glory (Ipomoea aquatica Forsk) exposed to 0 mg L(-1) to 2.50 mg L(-1) pentavalent V [V(V)] in Hoagland nutrient solutions. The concentration of chlorophyll a, chlorophyll b, and carotene peaked at a V(V) concentration of 0.05 mg L(-1) and gradually decreased at higher V(V) concentrations. Similarly, the plant biomass was stimulated at low levels of V(V) and was inhibited when V(V) concentrations exceeded 0.1 mg L(-1). Pentavalent V had negative effects on the uptake of phosphorus (P) by roots, shoots, and leaves. The biological absorption coefficients of V of the roots were higher than those of the aerial parts. Under low concentrations of V(V) exposure, the predominant species of V in the aerial parts was tetravalent V [V(IV)], whereas V(V) became more prevalent when concentrations of V(V) in the solution was higher than 0.50 mg L(-1). In the roots, however, the concentrations of V(V) were always higher than those of the V(IV), except in the control group. Organelles in the V(V)-treated leaves were distorted, and the periplasmic space became wider. These results indicate V(V) has concentration-dependent effects on the physiological properties of swamp morning glory, whereas the plant has the ability to develop self-protective function to adapt to the toxicity of V(V).

  16. Attenuation of circadian variation by combined antianginal therapy with suppression of morning and evening increases in transient myocardial ischemia

    DEFF Research Database (Denmark)

    Egstrup, K

    1991-01-01

    three 6-hour periods (p less than 0.01); a lesser peak was noted in the evening. The effects of metoprolol and combined therapy with metoprolol and nifedipine on the circadian variation of ischemic activity were studied in two subgroups of patients in a random, double-blind study design (31 patients...... receiving metoprolol and 42 receiving combined therapy). During therapy with metoprolol the morning increase in ischemic activity was attenuated, and the highest frequency of ischemia was then noted in the evening (6 AM to 12 noon compared with 6 PM to 12 midnight; p less than 0.05). Combined therapy...... abolished the morning peak as did metoprolol monotherapy, but even the evening increase in ischemic activity was attenuated (p less than 0.05). The diurnal distribution of the mean heart rate at the onset of ischemia, when patients were off therapy, showed a morning increase similar to the increase...

  17. The Effect of atmospheric humidity level to the determination of Islamic Fajr/morning prayer time and twilight appearance

    Science.gov (United States)

    Rohmah, Nihayatur

    2016-11-01

    Islamic prayer times are based on the astronomical position of the Sun in the sky. One of them is the Fajr prayer. It is marked by some indicators in the morning twilight which is white light spread in the Eastern horizon. However, determining the true time of twilight can be difficult. One of the reasons is the effect of atmospheric humidity to the appearance of morning twilight. The higher the humidity, the redder twilight sky appearance. This paper discusses this effect. It is shown that despite of the same Sun's position, sky color can vary considerably. Observations of various solar dip angle have been made to study this effect. Visibility for different angle can change accordingly. We obtained that the average solar dip for Fajr prayer by morning twilight images was -18°39'29.4".

  18. Herbage intake and ruminal digestion of dairy cows grazed on perennial ryegrass pasture either in the morning or evening.

    Science.gov (United States)

    Ueda, Koichiro; Mitani, Tomohiro; Kondo, Seiji

    2016-08-01

    This study aimed to clarify diurnal fluctuations of herbage intake, ruminal fermentation of herbage carbohydrates and proteins, and digesta particulate weight in the rumen of grazing dairy cows. Six ruminally cannulated, non-lactating dairy cows were grazed on perennial ryegrass/white clover pasture either in the morning (04.00 to 08.00 hours) or the evening (16.00 to 20.00 hours). Cows grazed in the evening spent more time (P dairy cows compared with morning grazing, in terms of ruminal fermentable energy intake and nitrogen utilization efficiency.

  19. Effects of short duration morning bright light in healthy elderly subjects. I: subjective feeling and ophthalmological examinations.

    Science.gov (United States)

    Fukuda, N; Kohsaka, M; Sasamoto, Y; Koyama, E; Kobayashi, R; Honma, H; Matsubara, H; Nakano, T; Sakakibara, S

    1998-04-01

    Seven aged subjects aged 61-78 years were exposed to 6000 lx bright light for 30 min during morning hours at their homes for 1 week. Visual analog scale was recorded before bedtime and after rising to assess subjective feelings. Ophthalmological examinations were made before and after light exposure, to exclude pre-existing ocular disorders and to detect ocular damage. Furthermore, ocular fatigue was self-evaluated immediately before and after exposure. Visual analog scale results indicated that alertness reduced significantly before bedtime. Ophthalmological abnormalities were not found after exposure. These findings suggest that short duration morning bright light exposure reduces night-time vigilance.

  20. Morning cortisol is lower in obese individuals with normal glucose tolerance

    Directory of Open Access Journals (Sweden)

    Praveen EP

    2011-09-01

    Full Text Available Edavan P Praveen1, Jaya Prakash Sahoo1, Bindu Kulshreshtha2, Madan L Khurana3, Nandita Gupta1, Sada Nand Dwivedi3, Guresh Kumar3, Ariachery C Ammini11Department of Endocrinology, All India Institute of Medical Sciences, 2Ram Manohar Lohia Hospital, 3Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, IndiaBackground: There is no consensus on the role of cortisol in the pathogenesis of obesity and metabolic syndrome (MS. This cross-sectional study aimed to analyze the relationship of morning plasma cortisol and adrenocorticotropic hormone (ACTH levels with body mass index (BMI and glucose tolerance.Subjects and methods: The sample frame was the “Offspring of individuals with diabetes study” database. A total of 358 offspring of individuals with type 2 diabetes mellitus (T2DM and 287 individuals without a known family history of T2DM were recruited for the study. Subjects who were ≥10 years of age were selected from the database for analysis. Subjects with T2DM were excluded. All participants underwent a 75 g oral glucose tolerance test (OGTT, and blood samples were collected at 0, 30, 60, and 120 minutes for glucose, insulin and C-peptide. Plasma cortisol, ACTH, and lipid profile were estimated from the fasting sample.Results: Four hundred and ninety-five participants (305 males [62%] and 190 females [38%] were included in the analysis. ACTH and cortisol levels were higher in normal-weight subjects than in overweight/obese subjects. Both ACTH and cortisol increased as fasting plasma glucose increased. Cortisol levels were significantly lower in offspring of T2DM subjects with MS than in offspring of T2DM subjects without MS. When adjusted for BMI, the significance was marginal. In males, cortisol levels were negatively correlated with early insulin secretion during OGTT (insulinogenic index [0–30] and positively with waist circumference and serum high-density lipoprotein cholesterol. In females, fasting

  1. Short-term variation in near-highway air pollutant gradients on a winter morning

    Directory of Open Access Journals (Sweden)

    J. L. Durant

    2010-09-01

    Full Text Available Quantification of exposure to traffic-related air pollutants near highways is hampered by incomplete knowledge of the scales of temporal variation of pollutant gradients. The goal of this study was to characterize short-term temporal variation of vehicular pollutant gradients within 200–400 m of a major highway (>150 000 vehicles/d. Monitoring was done near Interstate 93 in Somerville (Massachusetts from 06:00 to 11:00 on 16 January 2008 using a mobile monitoring platform equipped with instruments that measured ultrafine and fine particles (6–1000 nm, particle number concentration (PNC; particle-phase (>30 nm NO3, SO42−, and organic compounds; volatile organic compounds (VOCs; and CO2, NO, NO2, and O3. We observed rapid changes in pollutant gradients due to variations in highway traffic flow rate, wind speed, and surface boundary layer height. Before sunrise and peak traffic flow rates, downwind concentrations of particles, CO2, NO, and NO2 were highest within 100–250 m of the highway. After sunrise pollutant levels declined sharply (e.g., PNC and NO were more than halved and the gradients became less pronounced as wind speed increased and the surface boundary layer rose allowing mixing with cleaner air aloft. The levels of aromatic VOCs and NO3, SO42− and organic aerosols were generally low throughout the morning, and their spatial and temporal variations were less pronounced compared to PNC and NO. O3 levels increased throughout the morning due to mixing with O3-enriched air aloft and were generally lowest near the highway reflecting reaction with NO. There was little if any evolution in the size distribution of 6–225 nm particles with distance from the highway. These results suggest that to improve the accuracy of exposure estimates to near-highway pollutants

  2. The human endogenous circadian system causes greatest platelet activation during the biological morning independent of behaviors.

    Directory of Open Access Journals (Sweden)

    Frank A J L Scheer

    Full Text Available BACKGROUND: Platelets are involved in the thromboses that are central to myocardial infarctions and ischemic strokes. Such adverse cardiovascular events have day/night patterns with peaks in the morning (~9 AM, potentially related to endogenous circadian clock control of platelet activation. The objective was to test if the human endogenous circadian system influences (1 platelet function and (2 platelet response to standardized behavioral stressors. We also aimed to compare the magnitude of any effects on platelet function caused by the circadian system with that caused by varied standardized behavioral stressors, including mental arithmetic, passive postural tilt and mild cycling exercise. METHODOLOGY/PRINCIPAL FINDINGS: We studied 12 healthy adults (6 female who lived in individual laboratory suites in dim light for 240 h, with all behaviors scheduled on a 20-h recurring cycle to permit assessment of endogenous circadian function independent from environmental and behavioral effects including the sleep/wake cycle. Circadian phase was assessed from core body temperature. There were highly significant endogenous circadian rhythms in platelet surface activated glycoprotein (GP IIb-IIIa, GPIb and P-selectin (6-17% peak-trough amplitudes; p ≤ 0.01. These circadian peaks occurred at a circadian phase corresponding to 8-9 AM. Platelet count, ATP release, aggregability, and plasma epinephrine also had significant circadian rhythms but with later peaks (corresponding to 3-8 PM. The circadian effects on the platelet activation markers were always larger than that of any of the three behavioral stressors. CONCLUSIONS/SIGNIFICANCE: These data demonstrate robust effects of the endogenous circadian system on platelet activation in humans--independent of the sleep/wake cycle, other behavioral influences and the environment. The 9 AM timing of the circadian peaks of the three platelet surface markers, including platelet surface activated GPIIb-IIIa, the

  3. Circadian rhythm genes CLOCK and PER3 polymorphisms and morning gastric motility in humans.

    Directory of Open Access Journals (Sweden)

    Mitsue Yamaguchi

    Full Text Available Clock genes regulate circadian rhythm and are involved in various physiological processes, including digestion. We therefore investigated the association between the CLOCK 3111T/C single nucleotide polymorphism and the Period3 (PER3 variable-number tandem-repeat polymorphism (either 4 or 5 repeats 54 nt in length with morning gastric motility.Lifestyle questionnaires and anthropometric measurements were performed with 173 female volunteers (mean age, 19.4 years. Gastric motility, evaluated by electrogastrography (EGG, blood pressure, and heart rate levels were measured at 8:30 a.m. after an overnight fast. For gastric motility, the spectral powers (% normal power and dominant frequency (DF, peak of the power spectrum of the EGG were evaluated. The CLOCK and PER3 polymorphisms were determined by polymerase chain reaction (PCR restriction fragment length polymorphism analysis.Subjects with the CLOCK C allele (T/C or C/C genotypes: n = 59 showed a significantly lower DF (mean, 2.56 cpm than those with the T/T genotype (n = 114, 2.81 cpm, P < 0.05. Subjects with the longer PER3 allele (PER34/5 or PER35/5 genotypes: n = 65 also showed a significantly lower DF (2.55 cpm than those with the shorter PER34/4 genotype (n = 108, 2.83 cpm, P < 0.05. Furthermore, subjects with both the T/C or C/C and PER34/5 or PER35/5 genotypes showed a significantly lower DF (2.43 cpm, P < 0.05 than subjects with other combinations of the alleles (T/T and PER34/4 genotype, T/C or C/C and PER34/4 genotypes, and T/T and PER34/5 or PER35/5 genotypes.These results suggest that minor polymorphisms of the circadian rhythm genes CLOCK and PER3 may be associated with poor morning gastric motility, and may have a combinatorial effect. The present findings may offer a new viewpoint on the role of circadian rhythm genes on the peripheral circadian systems, including the time-keeping function of the gut.

  4. Effect of the angiotensin II receptor antagonist olmesartan on morning home blood pressure in hypertension: HONEST study at 16 weeks.

    Science.gov (United States)

    Kario, K; Saito, I; Kushiro, T; Teramukai, S; Ishikawa, Y; Hiramatsu, K; Kobayashi, F; Shimada, K

    2013-12-01

    Morning home blood pressure (BP) levels are more closely associated with cardiovascular risk than clinic BP levels. However, control of morning home BP has been worse than that of clinic BP in clinical practice. We examined the effects of olmesartan-based treatment using data (n=21 341) from the first 16 weeks of the Home BP measurement with Olmesartan Naive patients to Establish Standard Target blood pressure (HONEST) study, a prospective observational study for olmesartan-naive patients with essential hypertension. After 16-week olmesartan-based treatment, the clinic and morning home systolic BP (SBP) lowered from 151.6±16.4 and 153.6±19.0 mm Hg to 135.0±13.7 and 135.5±13.7 mm Hg, respectively (Polmesartan-based treatment, the proportion of patients with masked and white coat hypertension changed from 11.8 to 24.2% and 5.6 to 11.9%. In conclusion, both clinic and morning home BP in all, DM and CKD patients improved with 16-week olmesartan-based treatment in the 'real world', and the results showed a sustained 24-hour BP-lowering effect of olmesartan. Decrease in clinic and home BP resulted in an increased rate of masked and white coat hypertension, and further management is needed in those patients.

  5. Depictions of Alcohol Use in a UK Government Partnered Online Social Marketing Campaign: "Hollyoaks" "The Morning after the Night before"

    Science.gov (United States)

    Atkinson, Amanda Marie; Sumnall, Harry; Measham, Fiona

    2011-01-01

    Aims: This study analysed the depiction of alcohol in an online government partnered social marketing campaign: Hollyoaks "The Morning After the Night Before". This was a new initiative, providing Internet-delivered episodes of a popular terrestrial drama targeted at young people. Methods: All the 12 episodes were coded for "visual…

  6. Frequency and Types of Foods Advertised on Saturday Morning and Weekday Afternoon English- and Spanish-Language American Television Programs

    Science.gov (United States)

    Bell, Robert A.; Cassady, Diana; Culp, Jennifer; Alcalay, Rina

    2009-01-01

    Objective: To describe food advertised on networks serving children and youth, and to compare ads on English-language networks with ads on Spanish networks. Design: Analysis of television food advertisements appearing on Saturday morning and weekday afternoons in 2005-2006. A random sample of 1,130 advertisements appearing on 12 networks catering…

  7. Sleep-Wake Cycle, Daytime Sleepiness, and Attention Components in Children Attending Preschool in the Morning and Afternoon Shifts

    Science.gov (United States)

    Belísio, Aline S.; Kolodiuk, Fernanda F.; Louzada, Fernando M.; Valdez, Pablo; Azevedo, Carolina V. M.

    2017-01-01

    Children tend to sleep and wake up early and to exhibit daytime sleep episodes. To evaluate the impact of school start times on sleepiness and attention in preschool children, this study compared the temporal patterns of sleep, daytime sleepiness, and the components of attention between children aged 4-6 years that study in the morning (n = 66)…

  8. Virginia Tech Lumenhaus to be exhibited in Times Square, featured on ABC's Good Morning America, Jan. 28

    OpenAIRE

    Chadwick, Heather Riley

    2010-01-01

    The Virginia Tech Lumenhaus, an innovative, solar-powered house designed, constructed, and operated by students and faculty for the U.S. Department of Energy Solar Decathlon, will be exhibited in Times Square in New York City Jan. 27-31 and will be featured on ABC's Good Morning America on Thursday, Jan. 28.

  9. Depictions of Alcohol Use in a UK Government Partnered Online Social Marketing Campaign: "Hollyoaks" "The Morning after the Night before"

    Science.gov (United States)

    Atkinson, Amanda Marie; Sumnall, Harry; Measham, Fiona

    2011-01-01

    Aims: This study analysed the depiction of alcohol in an online government partnered social marketing campaign: Hollyoaks "The Morning After the Night Before". This was a new initiative, providing Internet-delivered episodes of a popular terrestrial drama targeted at young people. Methods: All the 12 episodes were coded for "visual…

  10. Effects of morning versus evening combined strength and endurance training on physical performance, muscle hypertrophy, and serum hormone concentrations.

    Science.gov (United States)

    Küüsmaa, Maria; Schumann, Moritz; Sedliak, Milan; Kraemer, William J; Newton, Robert U; Malinen, Jari-Pekka; Nyman, Kai; Häkkinen, Arja; Häkkinen, Keijo

    2016-12-01

    This study investigated the effects of 24 weeks of morning versus evening same-session combined strength (S) and endurance (E) training on physical performance, muscle hypertrophy, and resting serum testosterone and cortisol diurnal concentrations. Forty-two young men were matched and assigned to a morning (m) or evening (e) E + S or S + E group (mE + S, n = 9; mS + E, n = 9; eE + S, n = 12; and eS + E, n = 12). Participants were tested for dynamic leg press 1-repetition maximum (1RM) and time to exhaustion (Texh) during an incremental cycle ergometer test both in the morning and evening, cross-sectional area (CSA) of vastus lateralis and diurnal serum testosterone and cortisol concentrations (0730 h; 0930 h; 1630 h; 1830 h). All groups similarly increased 1RM in the morning (14%-19%; p muscle mass (time-of-day main effect; p muscle mass, while the E + S training order might be more beneficial for endurance performance development. However, training order and time seem to influence the magnitude of adaptations only when the training period exceeded 12 weeks.

  11. Natural association of two different betasatellites with Sweet potato leaf curl virus in wild morning glory (Ipomoea purpurea) in India.

    Science.gov (United States)

    Swapna Geetanjali, A; Shilpi, S; Mandal, Bikash

    2013-08-01

    Wild morning glory (Ipomoea purpurea) was observed to be affected by leaf curl and yellow vein diseases during summer-rainy season of 2009 in New Delhi, India. The virus was experimentally transmitted through whitefly, Bemisia tabaci to I. purpurea that reproduced the two distinct symptoms. Sequence analysis of multiple full-length clones obtained through rolling circle amplification from the leaf curl and yellow vein samples showed 91.8-95.3% sequence identity with Sweet potato leaf curl virus (SPLCV) and the isolates were phylogenetically distinct from those reported from Brazil, China, Japan and USA. Interestingly, two different betasatellites, croton yellow vein mosaic betasatellite and papaya leaf curl betasatellite were found with SPLCV in leaf curl and yellow vein diseases of I. purpurea, respectively. This study is the first report of occurrence of SPLCV in wild morning glory in India. SPLCV was known to infect other species of morning glory; our study revealed that I. purpurea, a new species of morning glory was a natural host of SPLCV. To date, betasatellite associated with SPLCV in Ipomoea spp. is not known. Our study provides evidence of natural association of two different betasatellites with SPLCV in leaf curl and yellow vein diseases of I. purpurea.

  12. Short blue light pulses (30 min) in the morning support a sleep-advancing protocol in a home setting

    NARCIS (Netherlands)

    Geerdink, Moniek; Walbeek, Thijs; Beersma, Dominicus; Hommes, V.; Gordijn, Margaretha

    2016-01-01

    Many people in our modern civilized society sleep later on free days compared to work days. This discrepancy in sleep timing will lead to so-called 'social jetlag' on work days with negative consequences for performance and health. Light therapy in the morning is often proposed as the most effective

  13. Effects of snoezelen, integrated in 24 h dementia care, on nurse-patient communication during morning care.

    NARCIS (Netherlands)

    Weert, J.C.M. van; Dulmen, A.M. van; Spreeuwenberg, P.M.M.; Ribbe, M.W.; Bensing, J.M.

    2005-01-01

    OBJECTIVE: To investigate the effectiveness of snoezelen, integrated in 24-hour care, on the communication of Certified Nursing Assistants (CNAs) and demented nursing home residents during morning care. METHODS: A quasi-experimental pre- and post-test design was conducted, comparing sic psychogeriat

  14. Effects of snoezelen, integrated in 24 h dementia care, on nurse–patient communication during morning care

    NARCIS (Netherlands)

    Weert, J.C.M. van; Dulmen, A.M. van; Spreeuwenberg, P.M.M.; Ribbe, M.W.; Bensing, J.

    2005-01-01

    Objective: To investigate the effectiveness of snoezelen, integrated in 24-hour care, on the communication of Certified Nursing Assistants (CNAs) and demented nursing home residents during morning care. Methods: A quasi-experimental pre- and post-test design was conducted, comparing sic psychogeriat

  15. Effects of snoezelen, integrated in 24 h dementia care, on nurse-patient communication during morning care

    NARCIS (Netherlands)

    Weert, van J.C.M.; Dulmen, van A.M.; Spreeuwenberg, P.M.M.; Ribbe, M.W.; Bensing, J.M.

    2005-01-01

    OBJECTIVE: To investigate the effectiveness of snoezelen, integrated in 24-hour care, on the communication of Certified Nursing Assistants (CNAs) and demented nursing home residents during morning care. METHODS: A quasi-experimental pre- and post-test design was conducted, comparing sic psychogeriat

  16. Food selectivity and diet switch can explain the slow feeding of herbivorous coral-reef fishes during the morning.

    Directory of Open Access Journals (Sweden)

    Ruth Khait

    Full Text Available Most herbivorous coral-reef fishes feed slower in the morning than in the afternoon. Given the typical scarcity of algae in coral reefs, this behavior seems maladaptive. Here we suggest that the fishes' slow feeding during the morning is an outcome of highly selective feeding on scarcely found green algae. The rarity of the food requires longer search time and extended swimming tracks, resulting in lower bite rates. According to our findings by noon the fish seem to stop their search and switch to indiscriminative consumption of benthic algae, resulting in apparent higher feeding rates. The abundance of the rare preferable algae gradually declines from morning to noon and seems to reach its lowest levels around the switch time. Using in situ experiments we found that the feeding pattern is flexible, with the fish exhibiting fast feeding rates when presented with ample supply of preferable algae, regardless of the time of day. Analyses of the fish's esophagus content corroborated our conclusion that their feeding was highly selective in the morning and non-selective in the afternoon. Modeling of the fishes' behavior predicted that the fish should perform a diel diet shift when the preferred food is relatively rare, a situation common in most coral reefs found in a warm, oligotrophic ocean.

  17. The Impact of Radiation on the GABLS3 Large-Eddy Simulation through the Night and during the Morning Transition

    NARCIS (Netherlands)

    Edwards, J.M.; Basu, S.; Bosveld, F.C.; Holtslag, A.A.M.

    2014-01-01

    Large-eddy simulation in the GABLS3 intercomparison is concerned with the developed stable boundary layer (SBL) and the ensuing morning transition. The impact of radiative transfer on simulations of this case is assessed. By the time of the reversal of the surface buoyancy flux, a modest reduction o

  18. Sleep-Wake Cycle, Daytime Sleepiness, and Attention Components in Children Attending Preschool in the Morning and Afternoon Shifts

    Science.gov (United States)

    Belísio, Aline S.; Kolodiuk, Fernanda F.; Louzada, Fernando M.; Valdez, Pablo; Azevedo, Carolina V. M.

    2017-01-01

    Children tend to sleep and wake up early and to exhibit daytime sleep episodes. To evaluate the impact of school start times on sleepiness and attention in preschool children, this study compared the temporal patterns of sleep, daytime sleepiness, and the components of attention between children aged 4-6 years that study in the morning (n = 66)…

  19. Nursing assistants' behavior during morning care: effects of the implementation of snoezelen, integrated in 24-hours dementia care.

    NARCIS (Netherlands)

    Weert, J.C.M. van; Janssen, B.M.; Dulmen, A.M. van; Spreeuwenberg, P.M.M.; Bensing, J.M.; Ribbe, M.W.

    2006-01-01

    Aim: This paper reports an investigation of the effects of the implementation of snoezelen, or multisensory stimulation, on the quality of nursing assistants' behaviour during morning care. Background: Nursing assistants in long-term dementia care are often unaware of the impact of their behaviour o

  20. Chronotype, Light Exposure, Sleep, and Daytime Functioning in High School Students Attending Morning or Afternoon School Shifts: An Actigraphic Study.

    Science.gov (United States)

    Martin, Jeanne Sophie; Gaudreault, Michael M; Perron, Michel; Laberge, Luc

    2016-04-01

    Adolescent maturation is associated with delays of the endogenous circadian phase. Consequently, early school schedules may lead to a mismatch between internal and external time, which can be detrimental to adolescent sleep and health. In parallel, chronotype is known to play a role in adolescent health; evening chronotype adolescents are at higher risk for sleep problems and lower academic achievement. In the summer of 2008, Kénogami High School (Saguenay, Canada) was destroyed by fire. Kénogami students were subsequently relocated to Arvida High School (situated 5.3 km away) for the 2008-2009 academic year. A dual school schedule was implemented, with Arvida students attending a morning schedule (0740-1305 h) and Kénogami students an afternoon schedule (1325-1845 h). This study aimed to investigate the effects of such school schedules and chronotype on sleep, light exposure, and daytime functioning. Twenty-four morning and 33 afternoon schedule students wore an actigraph during 7 days to measure sleep and light exposure. Academic achievement was obtained from school. Subjects completed validated questionnaires on daytime sleepiness, psychological distress, social rhythms, school satisfaction, alcohol, and chronotype. Overall, afternoon schedule students had longer sleep duration, lower sleepiness, and lower light exposure than morning schedule students. Evening chronotypes (E-types) reported higher levels of sleepiness than morning chronotypes (M-types) in both morning and afternoon schedules. Furthermore, M-types attending the morning schedule reported higher sleepiness than M-types attending the afternoon schedule. No difference was found between morning and afternoon schedule students with regard to academic achievement, psychological distress, social rhythms, school satisfaction, and alcohol consumption. However, in both schedules, M-type had more regular social rhythms and lower alcohol consumption. In summary, this study emphasizes that an early school

  1. Determinants of the Morning-Evening Home Blood Pressure Difference in Treated Hypertensives: The HIBA-Home Study

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    Lucas S. Aparicio

    2014-01-01

    Full Text Available Background. The morning home blood pressure (BP rise is a significant asymptomatic target organ damage predictor in hypertensives. Our aim was to evaluate determinants of home-based morning-evening difference (MEdiff in Argentine patients. Methods. Treated hypertensive patients aged ≥18 years participated in a cross-sectional study, after performing home morning and evening BP measurement. MEdiff was morning minus evening home average results. Variables identified as relevant predictors were entered into a multivariable linear regression analysis model. Results. Three hundred sixty-seven medicated hypertensives were included. Mean age was 66.2 (14.5, BMI 28.1 (4.5, total cholesterol 4.89 (1.0 mmol/L, 65.9% women, 11.7% smokers, and 10.6% diabetics. Mean MEdiff was 1.1 (12.5 mmHg systolic and 2.3 (6.1 mmHg diastolic, respectively. Mean self-recorded BP was 131.5 (14.1 mmHg systolic and 73.8 (7.6 mmHg diastolic, respectively. Mean morning and evening home BPs were 133.1 (16.5 versus 132 (15.7 systolic and 75.8 (8.4 versus 73.5 (8.2 diastolic, respectively. Significant beta-coefficient values were found in systolic MEdiff for age and smoking and in diastolic MEdiff for age, smoking, total cholesterol, and calcium-channel blockers. Conclusions. In a cohort of Argentine medicated patients, older age, smoking, total cholesterol, and use of calcium channel blockers were independent determinants of home-based MEdiff.

  2. Quality of Morning Report Courses in the Department of Infectious Diseases : A Prospective Study of Academic Members

    Directory of Open Access Journals (Sweden)

    Parviz Saleh

    2012-06-01

    Full Text Available Introduction: Morning report is one of the most important corner stones of medical train-ing and education in internal medicine training program. However, the pattern and exact template is not definitely described. Studying the quality of morning report courses helps to find out the weak and power points of the courses. The aim of this research is to study the quality of morning report courses prospectively with the assistance of the academic members, residents, and the students in the Department of Infectious Diseases at Tabriz University of Medical Sciences in 2010, Tabriz, Iran. Methods: In this cross-sectional study, the comments of the academic members, residents, and the students in the Infec-tious diseases course who attended to the morning report course meetings were collected utilizing two separate questionnaires about the goals of the classes. Results: The mean spending time for morning report classes was 60±20 minutes. 68.2% of participants were satisfied because of the acceptable discipline of the meetings. 57.85% of sessions were run by off call attendants. 95.2% of the reports were according to charts in the absence of the patients. In 47.1% of courses, the class management was teacher-centered. The ethical and social issues in 95.1% of cases have been observed. The evaluation of classes was gener-ally good. Conclusion: Although in this study the evaluation of meetings were generally good, it seems that the goals and the planning of the meetings should be revised.

  3. EFFECT OF MORNING AND EVENING RAMIPRIL TAKING ON AMBULATORY BLOOD PRESSURE PROFILE IN PATIENTS WITH ARTERIAL HYPERTENSION

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    V. M. Gorbunov

    2016-01-01

    Full Text Available Aim. To compare antihypertensive effect of ramipril monotherapy at morning and evening taking.Material and methods. 22 patients (10 men, 12 women; aged 62,1±1,9 y.o. with arterial hypertension of 1-2 stage were involved into the open randomized crossover study. Patients were randomized into 2 groups depending on ramipril taking time (morning or evening. Ambulatory blood pressure (BP monitoring (ABPM was performed. Patients of both groups were comparable in basic clinical characteristics and initial ABPM indices. Analysis of peak and phase characteristics of 24 hour BP profile was used as well as standard evaluation. Treatment duration was 3 weeks. Ramipril dose titration was made in 1,5 weeks. The average daily dose of ramipril was 6,1 mg in the morning taking, and 5,0 mg in the evening taking.Results. 20 patients finished study completely. 24 hour initial level of systolic (SBP and diastolic BP (DBP was 141,5±1,6/85,3±1,1 mm Hg. After ramipril monotherapy with evening taking BP reduced to 132,6±1,6/79,8±1,1 mm Hg (p<0,001 and with morning taking – to 131,8±1,6/79,2±1,1 mm Hg (p<0,001. Evening ramipril taking led to significant improvement of 24 hour BP profile. Night SBP/DBP reduction became deeper from 7,7±1,2/11,5±1,3% to 12,5±1,2/19,1±1,3 % (p<0,01. Morning taking did not have significant influence on these indices. Ramipril did not result in clinically significant hypotension including night one.Conclusion. Evening ramipril taking is effective and safe. It can be recommended to patients with insufficient night BP dipping (non dippers. 

  4. Subjective effects of caffeine among introverts and extraverts in the morning and evening.

    Science.gov (United States)

    Liguori, A; Grass, J A; Hughes, J R

    1999-08-01

    In previous studies of psychomotor performance, the stimulant effects of caffeine differed by personality characteristics. For example, caffeine improved the task performance of extraverts but overaroused introverts and thus impaired their performance. The present study compared the effects of caffeine on subjective arousal among introverts and extraverts. Seventeen introverts and 19 extraverts drank coffee that contained doses of 0, 2, and 4 mg/kg caffeine during morning and evening sessions in a within-subjects, randomized, double-blind, crossover design. At 30-min intervals for 180 min after drinking, participants completed the Profile of Mood States, a battery of self-report visual analog scales, and the Digit Symbol Substitution Test (DSST). Caffeine effects on mood and task performance did not significantly interact with extraversion, except for nonsignificant trends for caffeine to increase happiness and vigor more among extraverts than introverts. No 3-way interactions of group, time, and dose were found on any scales or on the DSST. Results do not support the hypothesis that caffeine differentially affects extraverts and introverts, particularly at different times of the day.

  5. La formule des traces tordue d’après le Friday Morning Seminar

    CERN Document Server

    Labesse, Jean-Pierre

    2013-01-01

    La formule des traces pour un groupe réductif connexe arbitraire est due à James Arthur. Le cas tordu a fait l'objet du Friday Morning Seminar à l'Institute for Advanced Study de Princeton pendant l'année académique 1983-1984. Lors de ce séminaire, des exposés ont été présentés par Laurent Clozel, Jean-Pierre Labesse et Robert Langlands. Les notes de ces exposés, rédigées dans l'urgence, avaient besoin d'être revues et complétées. L'ambition des auteurs du présent ouvrage est de donner, en s'appuyant sur ces notes, une preuve complète pour la formule des traces tordue, dans sa version primitive i.e. sa forme non invariante. Ceci est la première étape du projet de l'équipe parisienne animée par Laurent Clozel et Jean-Loup Waldspurger, dont le but est de donner une preuve complète de la stabilisation de la formule des traces tordue, qui est l'outil fondamental utilisé par J. Arthur dans son livre à paraître sur l'endoscopie tordue pour le groupe linéaire avec application aux groupes ...

  6. Blood pressure morning surge, exercise blood pressure response and autonomic nervous system.

    Science.gov (United States)

    Tanindi, Asli; Ugurlu, Murat; Tore, Hasan Fehmi

    2015-08-01

    We investigated blood pressure (BP) response to exercise with respect to BP morning surge (MS), and the association between MS, exercise treadmill test (ETT) and heart rate variability (HRV) indices. Eighty-four healthy subjects without hypertension were enrolled. Ambulatory BP monitoring and 24-hour Holter recordings were obtained for sleep-trough MS and HRV indices: low-frequency (LF) component, high-frequency (HF) component and LF/HF ratio. ETT was performed, and BPs were obtained at rest, end of each stage, and recovery. Third-minute heart rate recovery (HRR) and BP recovery ratio (BPRR) were calculated. When analysed in quartiles of MS, systolic BP at low workloads was higher in the highest than in the lowest quartile, although maximum BPs at maximum exercise were not significantly different. BPRR was highest in the highest quartile in contrast to HRR, which was lowest in the highest quartile. LF/HF was highest during both at daytime and night-time in the highest quartile. BPRR and LF/HF were positively, and HRR was inversely associated with MS. Subjects with a high MS have higher BP at low workloads, at which most daily activities are performed, and impairment in some indices, which indirectly reflect the autonomic nervous system.

  7. Wavelike Structures in the Turbulent Layer During the Morning Development of Convection at Dome C, Antarctica

    Science.gov (United States)

    Petenko, Igor; Argentini, Stefania; Casasanta, Giampietro; Kallistratova, Margarita; Sozzi, Roberto; Viola, Angelo

    2016-11-01

    In the period January-February 2014, observations were made at the Concordia station, Dome C, Antarctica to study atmospheric turbulence in the boundary layer using a high-resolution sodar. The turbulence structure was observed beginning from the lowest height of about 2 m, with a vertical resolution of less than 2 m. Typical patterns of the diurnal evolution of the spatio-temporal structure of turbulence detected by the sodar are analyzed. Here, we focus on the wavelike processes observed within the transition period from stable to unstable stratification occurring in the morning hours. Thanks to the high-resolution sodar measurements during the development of the convection near the surface, clear undulations were detected in the overlying turbulent layer for a significant part of the time. The wavelike pattern exhibits a regular braid structure, with undulations associated with internal gravity waves attributed to Kelvin-Helmholtz shear instability. The main spatial and temporal scales of the wavelike structures were determined, with predominant periodicity of the observed wavy patterns estimated to be 40-50 s. The horizontal scales roughly estimated using Taylor's frozen turbulence hypothesis are about 250-350 m.

  8. New sensitive serum melatonin radioimmunoassay employing the Kennaway G280 antibody: Syrian hamster morning adrenergic response.

    Science.gov (United States)

    Vaughan, G M

    1993-09-01

    A new procedure with the G280 antibody of Kennaway provides an assay for circulating melatonin (aMT) with a sample volume (200 microliters), an analytic (0.33 pg/ml) and functional (0.62-0.80 pg/ml) detectability, a 50% displacement dose (6.4 pg/ml), a Kd (0.657 pM), and measured circulating daytime levels lower than reported for previous procedures, and 100% assay recovery. The normal daytime range in adult human and Syrian hamster serum was 0.4-4 pg/ml. The pattern of fall of the nocturnal surge of Syrian hamster serum aMT near the time of lights-on was unaltered by extended darkness. Isoproterenol (ISO) injection 1 hr after lights-on, when aMT had reached daytime levels, raised serum and pineal aMT dramatically 2 hr postinjection. The same dose of ISO injected 4 hr into light produced only a small detectable increase. Novel extension of nocturnal darkness did not affect the responses to ISO. Thus, when they are allowed to occur at the usual time on a 10-hr dark schedule, both the fall from the nocturnal aMT surge and the subsequent loss of pineal beta-adrenergic responsiveness in this species occur endogenously (probably entrained) rather than from gating by acute effects of morning light. Changes in daytime serum aMT consistent with concomitant changes in the pineal can be measured with a sufficiently sensitive radioimmunoassay.

  9. NUTRITIONAL, METABOLIC AND CARDIOVASCULAR CORRELATIONS OF MORNING CORTISOL IN HEALTH CARE WORKERS IN A GASTROENTEROLOGY SERVICE

    Directory of Open Access Journals (Sweden)

    Aline GUERRA

    2015-06-01

    Full Text Available Background Workplace stress has been associated with obesity. Diminished body weight has also been anticipated in some contexts. Objective In a cohort of healthcare personnel, morning cortisol was compared to nutritional and metabolic variables, aiming to identify the correlates of such marker. Methods Population n=185, 33.8 ± 9.8 years, 88.1% females, body mass index (BMI 25.6 ± 4.4 kg/m2, included nurses and other nosocomial professionals, the majority with high social-economic status (75.2%. Participants were stratified according to BMI, fasting blood glucose (FBG and metabolic syndrome (MS. Fasting plasma cortisol and the Framingham Coronary Risk Score was calculated. Results Mean cortisol was acceptable (19.4 ± 7.9 µg/dL although with elevation in 21.6%. No correlation with FBG or MS occurred, and nonobese persons (BMI <25 exhibited the highest values (P=0.049. Comparison of the lowest and highest cortisol quartiles confirmed reduced BMI and waist circumference in the former, with unchanged Framingham Coronary Risk Score. Conclusion Cortisol correlated with reduced BMI. Despite low BMI and waist circumference, Framingham Coronary Risk Score was not benefitted, suggesting that exposure to cardiovascular risk continues, besides psychological strain. Initiatives to enhance organizational and staff health are advisable in the hospital environment.

  10. Studying the antiemetic effect of vitamin B6 for morning sickness: pyridoxine and pyridoxal are prodrugs.

    Science.gov (United States)

    Matok, Ilan; Clark, Shannon; Caritis, Steve; Miodovnik, Menachem; Umans, Jason G; Hankins, Gary; Mattison, Donald R; Koren, Gideon

    2014-12-01

    Vitamin B6 has been known to possess antiemetic effects since 1942. This water soluble compound has several forms in the circulation including pyridoxine, pyridoxal, and pyridoxal phosphate. The active antiemetic form of vitamin B6 is unknown. This was a pre-specified substudy of a randomized, placebo-controlled trial comparing the antiemetic effect of the doxylamine-vitamin B6 combination (Diclectin®) (n = 131) to placebo (n = 126) in women with nausea and vomiting of pregnancy. Serum concentrations of pyridoxine, pyridoxal, and pyridoxal 5' phosphate (PLP) and doxylamine were measured on Days 4, 8, and 15. With Diclectin® exhibiting a significant antiemetic effect in pregnancy, serum concentrations of pyridoxine were unmeasurable in almost all patients and those of pyridoxal were undetectable in half of patients. In contrast, PLP was measurable at sustained, stable steady-state levels in all patients. Our data suggest that there is a correlation between PLP levels and PUQE score of morning sickness symptoms when pyridoxine and pyridoxal levels are undetectable, and hence they might be prodrugs of PLP, which may be the active antiemetic form of vitamin B6.

  11. Original research in the classroom: why do zebrafish spawn in the morning?

    Science.gov (United States)

    Liang, Jennifer O; Abata, Katie; Bachelder, Eric; Bartley, Becca; Bozadjieva, Nadejda; Caskey, Victoria; Christianson, Benjamin; Detienne, Shannon; Dillon, Cassandra; Ecklund, Derek; Eckwright, David; Erickson, Raymond; Fadness, Tyler; Fealey, Michael; Fetter, Nicholas; Flatten, Michael; Fulton, Joshua; Galloway, Ryan; Gauer, Jacob; Hagler, Michael; Hammer, Andrea; Hasbargen, David; Heckmann, Brandon; Hildebrandt, Anne; Hillesheim, Jaclyn; Hoffman, Meghan; Hovey, Jonathan; Iverson, Sonja; Joyal, Matthew; Jubran, Rami; Keller, Stephanie; Kent, Derek; Kiefer, Brendan; King, Jacob; Kuefler, Aaron; Larson, Alex; Lewis, Nathan; Lu, Po-nien; Malone, Jessica; Mickolichek, Chelsey; Mitchell, Sean; Nelson, Pamela; Nemec, Michelle; Olsen, Shayna; Olson, Kendelle; Pautz, Kelsey; Pieper, Kelsey; Remackel, Michelle; Rengo, Cody; Sekenski, Jaime; Sievers, Tyson; Slavik, Brittney; Sloan, Jami; Smrekar, Candice; Stromquist, Emily; Tandberg, Patrick; Taurinskas, Nicholas; Thiele, Mark; Timinski, Peter; Tusa, Barite; Tuthill, Andrew; Uher, Bradley; Ward, Amy; Wilson, Luke; Young, Nathan

    2011-12-01

    As part of an upper level undergraduate developmental biology course at the University of Minnesota Duluth, we developed a unit in which students carried out original research as part of a cooperative class project. Students had the opportunity to gain experience in the scientific method from experimental design all of the way through to the preparation of publication on their research that included text, figures, and tables. This kind of inquiry-based learning has been shown to have many benefits for students, including increased long-term learning and a better understanding of the process of scientific discovery. In our project, students designed experiments to explore why zebrafish typically spawn in the first few hours after the lights come on in the morning. The results of our experiments suggest that spawning still occurs when the dark-to-light transition is altered or absent. This is consistent with the work of others that demonstrates that rhythmic spawning behavior is regulated by an endogenous circadian clock. Our successes and failures carrying out original research as part of an undergraduate course should contribute to the growing approaches for using zebrafish to bring the excitement of experimental science to the classroom.

  12. Nutritional, metabolic and cardiovascular correlations of morning cortisol in health care workers in a gastroenterology service.

    Science.gov (United States)

    Guerra, Aline; Soares, Rafael Marques; Pezzi, Fernanda; Karkow, Francisco Juarez; Faintuch, Joel

    2015-01-01

    Workplace stress has been associated with obesity. Diminished body weight has also been anticipated in some contexts. In a cohort of healthcare personnel, morning cortisol was compared to nutritional and metabolic variables, aiming to identify the correlates of such marker. Population n=185, 33.8 ± 9.8 years, 88.1% females, body mass index (BMI) 25.6 ± 4.4 kg/m2, included nurses and other nosocomial professionals, the majority with high social-economic status (75.2%). Participants were stratified according to BMI, fasting blood glucose (FBG) and metabolic syndrome (MS). Fasting plasma cortisol and the Framingham Coronary Risk Score was calculated. Mean cortisol was acceptable (19.4 ± 7.9 µg/dL) although with elevation in 21.6%. No correlation with FBG or MS occurred, and nonobese persons (BMI Framingham Coronary Risk Score. Cortisol correlated with reduced BMI. Despite low BMI and waist circumference, Framingham Coronary Risk Score was not benefitted, suggesting that exposure to cardiovascular risk continues, besides psychological strain. Initiatives to enhance organizational and staff health are advisable in the hospital environment.

  13. IMPACT OF MORNING STIFFNESS, EDUCATION, AND AGE ON THE FUNCTIONAL STATUS OF PATIENTS WITH RHEUMATOID ARTHRITIS.

    Science.gov (United States)

    Sahatçiu-Meka, Vjollca; Rexhepi, Sylejman; Manxhuka-Kerliu, Suzana; Pallaska, Kelmend; Murtezani, Ardiana; Osmani-Vllasolli, Teuta; Rexhepi, Mjellma; Rexhepi, Blerta

    2015-01-01

    The purpose of this study was to explore the relationship between disability status and duration of morning stiffness in hands with regard to age, level of education, and gender in patients with rheumatoid arthritis (RA). Also, the authors wanted to investigate this relationship with regard to the presence of rheumatoid factor, i.e., the serological status. A retrospective study was conducted in 250 patients with the classic form of RA (186 females, s64 males, mean age Xb = 49.96 y ears, range 25-60 years, disease duration 1-27 years, Xb = 6.41) previously diagnosed with RA according to the ACR (American College of Rheumatology 1987 criteria). All patients were in Steinbrocker functional classes II and III. The probability level was expressed by p 0.05) seronegative, (r = 0.12, y = 0.00x + 2.30, p > 0.05) seropositive]. High positive values were obtained for the linear correlation coefficient between duration of the disease and functional class (p high values were obtained regarding the coefficient of correlation between age and functional class [(r = 0.29, p disability. Functional disability increased with the duration of the disease, depended on age and educational level, and was more pronounced in older age, regardless of RA serological status. With regard to serological status and sex, the differences were non-significant.

  14. GEOS-2 observations of energetic electrons in the morning sector during auroral radio absorption events

    Energy Technology Data Exchange (ETDEWEB)

    Collis, P.N.; Korth, A.

    1985-04-01

    The temporal development of two auroral absorption events in the morning sector is compared with simultaneous observations of electrons from the satellite GEOS-2, utilizing the good energy resolution over the range 15-300 keV to show that the electrons effective in contributing to the observed radio absorption are confined to the range 30-130 keV. By far the most important are those below 80 keV, and as a geophysical monitor the riometer may be considered an efficient indicator of electron fluxes of energy typically of 60-70 keV. The ionospheric effects of the precipitated fluxes are predicted, and the results used to discuss the validity of the model atmosphere and of the profiles of effective recombination coefficient and specific absorption. Integration of the calculated profiles of incremental radio absorption yields total estimates within 30 percent of the observed intensities. The absorbing layer maximizes at altitudes of 85-90 km and has a typical half-height of 25 km. It is shown further that the electron-flux characteristics are consistent with gradient-curvature drift from a particle source in the midnight sector. 33 references.

  15. Morning and Evening Oscillators Cooperate to Reset Circadian Behavior in Response to Light Input

    Directory of Open Access Journals (Sweden)

    Pallavi Lamba

    2014-05-01

    Full Text Available Light is a crucial input for circadian clocks. In Drosophila, short light exposure can robustly shift the phase of circadian behavior. The model for this resetting posits that circadian photoreception is cell autonomous: CRYPTOCHROME senses light, binds to TIMELESS (TIM, and promotes its degradation, which is mediated by JETLAG (JET. However, it was recently proposed that interactions between circadian neurons are also required for phase resetting. We identify two groups of neurons critical for circadian photoreception: the morning (M and the evening (E oscillators. These neurons work synergistically to reset rhythmic behavior. JET promotes acute TIM degradation cell autonomously in M and E oscillators but also nonautonomously in E oscillators when expressed in M oscillators. Thus, upon light exposure, the M oscillators communicate with the E oscillators. Because the M oscillators drive circadian behavior, they must also receive inputs from the E oscillators. Hence, although photic TIM degradation is largely cell autonomous, neural cooperation between M and E oscillators is critical for circadian behavioral photoresponses.

  16. Reevaluation of the role of duration of morning stiffness in the assessment of rheumatoid arthritis activity.

    Science.gov (United States)

    Khan, Nasim A; Yazici, Yusuf; Calvo-Alen, Jaime; Dadoniene, Jolanta; Gossec, Laure; Hansen, Troels M; Huisman, Margriet; Kallikorm, Riina; Muller, Raili; Liveborn, Margareth; Oding, Rolf; Luchikhina, Elena; Naranjo, Antonio; Rexhepi, Sylejman; Taylor, Peter; Tlustochowich, Witold; Tsirogianni, Afrodite; Sokka, Tuulikki

    2009-11-01

    To evaluate the utility of the duration of morning stiffness (MS), as a patient-reported outcome (PRO), in assessing rheumatoid arthritis (RA) disease activity. We acquired information on 5439 patients in QUEST-RA, an international database of patients with RA evaluated by a standard protocol. MS duration was assessed from time of waking to time of maximal improvement. Ability of MS duration to differentiate RA activity states, based on Disease Activity Score (DAS)28, was assessed by analysis of variance; and a receiver-operating characteristic (ROC) curve was plotted for discriminating clinically active (DAS28 > 3.2) from less active (DAS28 PRO index based on physical function, pain, and general health (GH), in predicting the 3-variable DAS28 (DAS28v3). MS duration had moderate correlation (r = 0.41-0.48) with pain, Health Assessment Questionnaire, and GH; and weak correlation (r = 0.23-0.39) with joint counts and erythrocyte sedimentation rate. MS duration differed significantly among patients with different RA activity (p 3.2). MS duration has a moderate correlation with RA disease activity. Assessment of MS duration may be clinically helpful in patients with low RAPID3 scores.

  17. Desempenho e características de carcaça do escargot francês (Helix aspersa maxima alimentado com rações contendo diferentes óleos vegetais Performance and carcass characteristics of “gros gris” (Helix aspersa maxima fed with different vegetable oils in diets

    Directory of Open Access Journals (Sweden)

    Carmino Hayashi

    2004-02-01

    Full Text Available Objetivando avaliar a utilização de óleos vegetais de diferentes origens em rações no desempenho e características de carcaça do escargot francês “gros gris” (Helix aspersa maxima, 240 animais com peso inicial médio de 0,11g, foram distribuídos em um delineamento inteiramente casualizado com seis tratamentos e quatro repetições com dez animais cada, em aquários de 12L. As rações foram formuladas de forma a diferirem quanto ao emprego (3 % da ração dos óleos de soja, canola, girassol, linhaça, arroz e milho. Os valores médios de peso final, conversão alimentar, taxa de eficiência protéica, rendimento de carcaça, percentagem de concha e taxa de sobrevivência dos animais alimentados com as rações com os diferentes óleos não diferiram (p>0,01 entre si. Os teores de umidade, cinza, proteína bruta e lipídeos totais e a relação ácidos graxos poliinsaturados/ácidos graxos saturados da porção comestível dos animais submetidos as diferentes rações não foram influenciados (p>0,05. Entretanto, os animais que receberam dieta com óleo de linhaça apresentaram o melhor (p0,05 nos teores de umidade e cinza das conchas dos animais submetidos às diferentes rações. Por outro lado, os animais que receberam óleo de linhaça tiveram concha com menor (pAiming to evaluate the use of different vegetable oil sources on performance and carcass characteristics of “gros gris” (Helix aspersa maxima diets, two hundred forty snails with initial average weight of 0.11g samples were distributed in an entirely randomized design with six treatments and four replications in twelve-liter aquaria. The diets were formulated to have differences on soybean, canola, sunflower, linseed, rice and corn oil inclusion at 3% of the diet. The average final weight, feed conversion, protein efficiency rate, carcass yields, percentage of shell and survival rates were not affected (p>0.01 by the use of different oils. The moisture, ash, crud

  18. Reappraisal of the diagnostic and prognostic value of morning stiffness in arthralgia and early arthritis: Results from the Groningen EARC, Leiden EARC, ESPOIR, Leiden EAC and REACH

    NARCIS (Netherlands)

    J.A.B. van Nies (Jessica A.B.); C. Alves (Celina); A.L.S. Radix-Bloemen (Audrey L.S.); C. Gaujoux-Viala (Cécile); T.W.J. Huizinga (Tom); J.M.W. Hazes (Mieke); E. Brouwer (Eric); B. Fautrel (Bruno); Mil, A.H.M.H.-V. (Annette H.M. van der Helm-van)

    2015-01-01

    textabstractIntroduction: Morning stiffness is assessed daily in the diagnostic process of arthralgia and arthritis, but large-scale studies on the discriminative ability are absent. This study explored the diagnostic value of morning stiffness in 5,202 arthralgia and arthritis patients and the prog

  19. Reappraisal of the diagnostic and prognostic value of morning stiffness in arthralgia and early arthritis : results from the Groningen EARC, Leiden EARC, ESPOIR, Leiden EAC and REACH

    NARCIS (Netherlands)

    van Nies, Jessica A. B.; Alves, Celina; Radix-Bloemen, Audrey L. S.; Gaujoux-Viala, Cecile; Huizinga, Tom W. J.; Hazes, Johanna M. W.; Brouwer, Elisabeth; Fautrel, Bruno; van der Helm-van Mil, Annette H. M.

    2015-01-01

    Introduction: Morning stiffness is assessed daily in the diagnostic process of arthralgia and arthritis, but large-scale studies on the discriminative ability are absent. This study explored the diagnostic value of morning stiffness in 5,202 arthralgia and arthritis patients and the prognostic value

  20. Asymmetric time interval between evening and morning milking and its effect on the total daily milk yield

    Directory of Open Access Journals (Sweden)

    Gustav Chládek

    2011-01-01

    Full Text Available Samples of milk obtained in the course of evening and morning milking performed in variable time intervals of either 11 and 13 hours (n = 1.282 or 10 and 14 hours (n = 370 were collected with the aim to quantify the effect of the length of a variable (asymmetric time interval between evening and morning milking on the total amount and composition of daily milk production of dairy cows. Milk samples were analysed in an accredited (EN ISO 17025 laboratory in Brno-Tuřany (Czech Republic and the following contents of individual milk components were estimated: fat (F; g.100g−1, total protein (TP; g.100g−1, lactose (L; lactose monohydrate; g.100g−1, and somatic cell counts (SCC; ­103.ml−1 were estimated in. It was found out that with the increasing total daily milk production the shares of evening and morning milk yield increased as well; however, the percentages of evening and/or morning yields in the total yield remained practically unchanged and represented 43.5 % and 56.5% or 40.4 % and 59.6 % in variants with intervals of 11 and 13 hours and/or 10 and 14 hours, respectively. In the variant with the milking interval of 11 and 13 hours, values of correlation coefficients between the above parameters (i.e. F, TP, L, SCC, and log SCC of evening and morning milk yields on the one hand and the total milk performance on the other ranged from the minimum r = 0.896 (F to the maximum r = 0.980 (TP. In the variant with the interval of 10 and 14 hours, the corresponding values of correlation coefficients were r = 0.848 (F and r = 0.983 (TP. These correlations were statistically highly significant in all cases (P ≤ 0.001. Further, linear regression equations enabling the estimation of milk parameters of the total milk yield on the base of results obtained in evening and morning milking was calculated as well. Values of coefficients of determination (R2 of these equations ranged from 0.803 (F to 0.960 (TP and from 0.718 (F to 0.966 (TP for

  1. Orbitofrontal gray matter relates to early morning awakening: a neural correlate of insomnia complaints?

    Science.gov (United States)

    Stoffers, Diederick; Moens, Sarah; Benjamins, Jeroen; van Tol, Marie-José; Penninx, Brenda W J H; Veltman, Dick J; Van der Wee, Nic J A; Van Someren, Eus J W

    2012-01-01

    Sleep complaints increase profoundly with age; prevalence estimates of insomnia in the elderly reach up to 37%. The three major types of nocturnal complaints are difficulties initiating (DIS) and maintaining (DMS) sleep and early morning awakening (EMA), of which the latter appears most characteristic for aging. The neural correlates associated with these complaints have hardly been investigated, hampering the development of rational treatment and prevention. A recent study on structural brain correlates of insomnia showed that overall severity, but not duration, of insomnia complaints is associated with lower gray matter (GM) density in part of the left orbitofrontal cortex (OFC). Following up on this, we investigated, in an independent sample of people not diagnosed with insomnia, whether individual differences in GM density are associated with differences in DIS, DMS, and EMA. Sixty five healthy participants (mean age = 41 years, range 18-56) filled out questionnaires and underwent structural magnetic resonance imaging. Three compound Z-scores were computed for questionnaire items relating to DIS, DMS, and EMA. Whole-brain voxel-based morphometry was used to investigate their association with GM density. Results show that participants with lower GM density in a region where the left inferior OFC borders the insula report more EMA, but not DIS or DMS. This is the first study to investigate structural brain correlates of specific sleep characteristics that can translate into complaints in insomniacs. The selective association of EMA with orbitofrontal GM density makes our findings particularly relevant to elderly people, where EMA represents the most characteristic complaint. It is hypothesized that low GM density in aforementioned orbitofrontal area affects its role in sensing comfort. An intact ability to evaluate comfort may be crucial to maintain sleep, especially at the end of the night when sleep is vulnerable because homeostatic sleep propensity has

  2. Memory and mood during the night and in the morning after repeated evening doses of MDMA.

    Science.gov (United States)

    Kuypers, K P C; Wingen, M; Ramaekers, J G

    2008-11-01

    Previously it has been shown that MDMA causes memory impairment during daytime testing. However, MDMA is usually taken in the evening or during the night. In addition, it is known that sleep deprivation also causes memory impairment. The present study aimed to assess whether evening doses of MDMA added to, or interacted with the memory impairment due to sleep deprivation. Fourteen healthy subjects participated in a double-blind, placebo-controlled, two-way cross-over study. Treatments consisted of MDMA 75 and 50 mg divided over the evening or double placebo. Memory tests and subjective measures of mood were conducted at baseline and three times post dosing that is at 6.30 pm, 9.30 pm, 1.30 am and 7 am, respectively -1.5, 1.5, 5.5 and 11 h relative to drug intake (first dose). Memory performance detoriated progessively over time as a function of sleep loss, independent of treatment. MDMA added to this impairment as indicated by a significant main effect of MDMA on verbal and spatial memory performance. Mood ratings and response speed revealed an MDMA by Time interaction. After administration of MDMA response speed improved and feelings of vigor, friendliness, elation, anxiety, confusion, arousal and positive mood increased in magnitude during the night, while all these parameters returned to placebo-like levels on the final morning session. It is concluded that evening doses of MDMA selectively impair memory performance, and that this impairment is additional to the effect of sleep deprivation on memory performance.

  3. Milk-based phospholipids increase morning cortisol availability and improve memory in chronically stressed men.

    Science.gov (United States)

    Schubert, Melanie; Contreras, Carina; Franz, Nadin; Hellhammer, Juliane

    2011-06-01

    Phospholipids (PLs) have been shown to dampen the activity and reactivity of the hypothalamic-pituitary-adrenal axis (HPAA). To further investigate stress protective effects of PL, 75 chronically stressed men aged 30 to 51 years were enrolled in a randomized and placebo-controlled trial. The subjects received a bovine milk drink with either 0.5% PL, 1% PL, or a placebo for 42 days to test the hypothesis that supplementation with specific phospholipids would normalize the cortisol response of the HPAA. For determining HPAA activity, the cortisol awakening response was studied before and after treatment. In addition, participants were exposed to an acute stressor, the Trier Social Stress Test, to assess treatment effects on stress reactivity and stress-related memory impairment. After receiving PL-enriched milk, both PL groups showed a delayed decline from peak levels in morning salivary cortisol, suggesting a prolonged availability of free cortisol. Treatment with 0.5% PL additionally resulted in a stronger increase of cortisol after awakening, whereas no such differences could be observed in the 1% PL group and the placebo group, respectively. The acute stress response did not significantly differ among placebo and PL groups. An exploratory data analysis further revealed that elderly participants receiving the higher PL dosage had a significant better memory performance after the Trier Social Stress Test as compared with elderly participants from the placebo and low-PL dosage group; no such difference was observed at baseline. Our results suggest that PL may increase the availability of cortisol in chronically stressed men and may attenuate stress-induced memory impairments. Results of the present study are discussed within the context of previous research and current state of knowledge. Copyright © 2011 Elsevier Inc. All rights reserved.

  4. Is cortisol excretion independent of menstrual cycle day? A longitudinal evaluation of first morning urinary specimens.

    Directory of Open Access Journals (Sweden)

    Pablo A Nepomnaschy

    Full Text Available BACKGROUND: Cortisol is frequently used as a marker of physiologic stress levels. Using cortisol for that purpose, however, requires a thorough understanding of its normal longitudinal variability. The current understanding of longitudinal variability of basal cortisol secretion in women is very limited. It is often assumed, for example, that basal cortisol profiles do not vary across the menstrual cycle. This is a critical assumption: if cortisol were to follow a time dependent pattern during the menstrual cycle, then ignoring this cyclic variation could lead to erroneous imputation of physiologic stress. Yet, the assumption that basal cortisol levels are stable across the menstrual cycle rests on partial and contradictory evidence. Here we conduct a thorough test of that assumption using data collected for up to a year from 25 women living in rural Guatemala. METHODOLOGY: We apply a linear mixed model to describe longitudinal first morning urinary cortisol profiles, accounting for differences in both mean and standard deviation of cortisol among women. To that aim we evaluate the fit of two alternative models. The first model assumes that cortisol does not vary with menstrual cycle day. The second assumes that cortisol mean varies across the menstrual cycle. Menstrual cycles are aligned on ovulation day (day 0. Follicular days are assigned negative numbers and luteal days positive numbers. When we compared Models 1 and 2 restricting our analysis to days between -14 (follicular and day 14 (luteal then day of the menstrual cycle did not emerge as a predictor of urinary cortisol levels (p-value>0.05. Yet, when we extended our analyses beyond that central 28-day-period then day of the menstrual cycle become a statistically significant predictor of cortisol levels. SIGNIFICANCE: The observed trend suggests that studies including cycling women should account for day dependent variation in cortisol in cycles with long follicular and luteal phases.

  5. Morning rise of blood pressure and subcutaneous small resistance artery structure.

    Science.gov (United States)

    Rizzoni, Damiano; Porteri, Enzo; Platto, Caterina; Rizzardi, Nicola; De Ciuceis, Carolina; Boari, Gianluca E M; Muiesan, Maria Lorenza; Salvetti, Massimo; Zani, Francesca; Miclini, Marco; Paiardi, Silvia; Castellano, Maurizio; Rosei, Enrico Agabiti

    2007-08-01

    It has been previously demonstrated that the morning rise (MoR) of blood pressure (BP) may predict major cardiovascular events in hypertensive patients. Structural alterations of small resistance arteries, as evaluated by the tunica media to internal lumen ratio (M/L) of subcutaneous small resistance arteries, may also predict cardiovascular events. Because an increased M/L may amplify the effect of hypertensive stimuli, the present study aimed to evaluate the possible relationships between MoR and M/L in a population of hypertensive patients. Sixty-four patients with essential hypertension were included in the present study. All patients were submitted to a biopsy of subcutaneous fat. Small resistance arteries were dissected and mounted on an isometric myograph, and the M/L was measured. In addition, MoR was calculated from ambulatory blood pressure monitoring (ABPM) according to four previously published different methods (MoR1 to MoR4). A statistically significant correlation was observed between M/L and MoR1 (r = 0.52, P < 0.001), MoR2 (r = 0.32, P < 0.01), MoR3 (r = 0.25, P < 0.05) and MoR4 (r = 0.27, P < 0.05), as well as between internal diameter of subcutaneous small arteries and MoR1 (r = -0.45, P < 0.001) and MoR2 (r = -0.28, P < 0.05). Our results indicate that subcutaneous small artery structure is related to MoR, possibly because an altered vascular structure may amplify BP changes or, vice versa, because a greater MoR may further damage peripheral vasculature.

  6. Orbitofrontal gray matter relates to early morning awakening: a neural correlate of insomnia complaints?

    Directory of Open Access Journals (Sweden)

    Diederick eStoffers

    2012-06-01

    Full Text Available Sleep complaints increase profoundly with age; prevalence estimates of insomnia in elderly people reach up to 37%. The three major types of nocturnal complaints are difficulties initiating sleep (DIS, difficulties maintaining sleep (DMS and early morning awakening (EMA, of which the latter appears most characteristic for aging. The neural correlates associated with these complaints have hardly been investigated, hampering the development of rational treatment and prevention. A recent study on structural brain correlates of insomnia showed that overall severity, but not duration, of insomnia complaints is associated with lower gray matter (GM density in part of the left orbitofrontal cortex. Following up on this, we investigated, in an independent sample of people not diagnosed with insomnia, whether individual differences in GM density are associated with differences in DIS, DMS and EMA.65 healthy participants filled out questionnaires and underwent structural magnetic resonance imaging. Three compound Z-scores were computed for questionnaire items relating to DIS, DMS and EMA. Whole-brain voxel-based morphometry was used to investigate their association with GM density. Results show that participants with lower GM density in a region where the left inferior orbitofrontal cortex borders the insula report more EMA, but not DIS or DMS.This is the first study to investigate structural brain correlates of specific sleep characteristics that can translate into complaints in insomniacs. The selective association of EMA with orbitofrontal GM density makes our findings particularly relevant to elderly people, where EMA represents the most characteristic complaint. It is hypothesized that low GM density in aforementioned orbitofrontal area affects its role in sensing comfort. An intact ability to evaluate comfort may be crucial to maintain sleep, especially at the end of the night when sleep is vulnerable because homeostatic sleep propensity has

  7. Work/non-workday differences in mother, child, and mother-child morning cortisol in a sample of working mothers and their children.

    Science.gov (United States)

    Hibel, Leah C; Trumbell, Jill M; Mercado, Evelyn

    2014-01-01

    Mothers have been shown to have higher morning cortisol on days they go to work compared to non-workdays; however, it is unknown how maternal workday associates with child morning cortisol or the attunement of mother-child morning cortisol. This study examined the presence and stability of morning cortisol levels and slopes (i.e., cortisol awakening response or CAR) in a sample of 2-4year old children in out-of-home child care with working mothers. In addition, we examined the differential contributions of maternal workday on mother-child attunement in morning cortisol. Mother and child morning cortisol was sampled twice a day (awakening and 30min later) across four consecutive days (2 non-workdays; 2 workdays) among 47 working mothers and their young children. Mothers also reported on compliance with sampling procedures and provided demographic information. While children exhibited stability in cortisol levels, children's CARs were variable, with children's non-work CARs not predictive of work CARs. Similarly, a significant morning rise in cortisol was only found on workdays, not non-workdays. Overall, mothers had higher cortisol levels and steeper CARs than their children. Further, maternal workday moderated the attunement of mother-child morning cortisol, such that mothers and children had concordant cortisol levels on non-workdays, but discordant cortisol levels on workdays. Morning cortisol may be more variable in pre-school aged children than adults but may be similarly responsive to the social environment. Further, workday mornings may be a time of reduced mother-child cortisol attunement. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Temporal variability in urinary phthalate metabolite excretion based on spot, morning, and 24-h urine samples: Considerations for epidemiological studies

    DEFF Research Database (Denmark)

    Frederiksen, Hanne; Kranich, Selma K.; Jørgensen, Niels;

    2013-01-01

    Urinary phthalate excretion is used as marker of phthalate exposure in epidemiological studies. Here we examine the reliability of urinary phthalate levels in exposure classification by comparing the inter- and intrasubject variation of urinary phthalate metabolite levels. Thirty-three young...... healthy men each collected two spot, three first-morning, and three 24-h urine samples during a 3-month period. Samples were analyzed for the content of 12 urinary metabolites of 7 different phthalates. Variability was assessed as intraclass correlation coefficients (ICC). For the metabolites of diethyl...... of exposures for these two phthalates in population studies and hence an attenuation of the power to detect possible exposure-outcome associations. The only slightly higher ICCs for 24-h pools compared to first-morning and spot urine samples does not seem to justify the extra effort needed to collect 24-h...

  9. Morning Salivary Cortisol in Young Children: Reference Values and the Effects of Age, Sex, and Acute Bronchiolitis.

    Science.gov (United States)

    Rolfsjord, Leif Bjarte; Bakkeheim, Egil; Berents, Teresa Løvold; Alm, Johan; Skjerven, Håvard Ove; Carlsen, Kai-Håkon; Mowinckel, Petter; Sjöbeck, Ann-Christine; Carlsen, Karin Cecilie Lødrup

    2017-05-01

    To identify morning salivary cortisol reference values in infancy and at 2 years of age and to investigate the influence of age, sex and acute bronchiolitis. In this South-East Norwegian cohort study, 308 children hospitalized with moderate to severe acute bronchiolitis in infancy in 2010-2011 were compared with 223 healthy controls included in 2012 by measuring morning salivary cortisol levels at inclusion and at 2 years of age. Samples were collected shortly after awakening after 6 am. The influences of age, sex, and acute bronchiolitis were assessed by regression analysis. In infancy, cortisol values were higher in acute bronchiolitis, with an age- and sex-adjusted weighted mean group difference of 13.9 nmol/L (95% CI 8.1-19.7; P bronchiolitis than in healthy infants. ClinicalTrials.gov: NCT00817466. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  10. “Always the same stairs, always the same room”: the uncanny architecture of Jean Rhys's Good morning, midnight

    OpenAIRE

    Zimmerman, Emma

    2015-01-01

    Jean Rhys’s Good Morning, Midnight (1939) is a novel that returns obsessively to the uncanny architecture of the Parisian hotel, through providing insight into the deracinated experiences of protagonist Sasha Jansen, a woman existing at the peripheries of the interwar city. Strikingly, this uncanny architecture structures the narrative itself, in the form of frequent disruptions in temporality, stylistic negotiations of memory, and distinct fragmented typography. An architectural interpretati...

  11. Emotional Experience in the Mornings and the Evenings: Consideration of Age Differences in Specific Emotions by Time of Day

    Directory of Open Access Journals (Sweden)

    Tammy eEnglish

    2014-03-01

    Full Text Available Considerable evidence points to age-related improvements in emotional well-being with age. In order to gain a more nuanced understanding of the nature of these apparent shifts in experience, we examined age differences in a range of emotional states in the mornings and evenings in a sample of 135 community-residing participants across 10 consecutive days. Participants ranged in age from 22 to 93 years. Each participant completed a diary in the morning and again in the evening every day for the study period. During each of the assessments, participants reported the degree to which they experienced emotions sampled from all four quadrants of the affective circumplex. Overall, participants felt less positive and more negative in the evenings than in the mornings. As expected, older adults reported a relatively more positive emotional experience than younger adults at both times of day. Importantly, however, age effects varied based on emotion type and time of day. Older adults reported experiencing more positive emotion than relatively younger adults across a range of different positive states (although age differences emerged most consistently for low arousal positive states. Age-related reductions in negative experience were observed only for reports of low arousal negative emotions. There were no age differences in anger, anxiety, or sadness. For some emotions, age differences were stronger in the mornings (e.g., relaxed whereas for other emotions age differences were more pronounced in the evenings (e.g., enthusiastic. Findings are discussed in the context of adulthood changes in motivation and emotional experience.

  12. Emotional experience in the mornings and the evenings: consideration of age differences in specific emotions by time of day.

    Science.gov (United States)

    English, Tammy; Carstensen, Laura L

    2014-01-01

    Considerable evidence points to age-related improvements in emotional well-being with age. In order to gain a more nuanced understanding of the nature of these apparent shifts in experience, we examined age differences in a range of emotional states in the mornings and evenings in a sample of 135 community-residing participants across 10 consecutive days. Participants ranged in age from 22 to 93 years. Each participant completed a diary in the morning and again in the evening every day for the study period. During each of the assessments, participants reported the degree to which they experienced emotions sampled from all four quadrants of the affective circumplex. Overall, participants felt less positive and more negative in the evenings than in the mornings. As expected, older adults reported a relatively more positive emotional experience than younger adults at both times of day. Importantly, however, age effects varied based on emotion type and time of day. Older adults reported experiencing more positive emotion than relatively younger adults across a range of different positive states (although age differences emerged most consistently for low arousal positive states). Age-related reductions in negative experience were observed only for reports of low arousal negative emotions. There were no age differences in anger, anxiety, or sadness. For some emotions, age differences were stronger in the mornings (e.g., relaxed) whereas for other emotions age differences were more pronounced in the evenings (e.g., enthusiastic). Findings are discussed in the context of adulthood changes in motivation and emotional experience.

  13. Effect of extended morning fasting upon ad libitum lunch intake and associated metabolic and hormonal responses in obese adults

    OpenAIRE

    Chowdhury, E. A.; Richardson, J. D.; Tsintzas, K; Thompson, D.; Betts, J A

    2015-01-01

    Background/Objectives: Breakfast omission is positively associated with obesity and increased risk of disease. However, little is known about the acute effects of extended morning fasting upon subsequent energy intake and associated metabolic/regulatory factors in obese adults. Subjects/Methods: In a randomised cross-over design, 24 obese men (n=8) and women (n=16) extended their overnight fast by omitting breakfast consumption or ingesting a typical carbohydrate-rich breakfast of 2183±393 kJ...

  14. Long-term impact of role stress and cognitive rumination upon morning and evening saliva cortisol secretion.

    Science.gov (United States)

    Rydstedt, Leif W; Cropley, Mark; Devereux, Jason

    2011-05-01

    The long-term impact of role stress (conflict and ambiguity), cognitive rumination and their interaction were analysed upon morning and evening saliva cortisol secretion. The sample consisted of 52 male and 24 female British white-collars who had participated in a survey study on psychosocial working conditions 3.5 years earlier. Saliva cortisol secretion was measured over seven consecutive days with two measures: in the morning on awakening and at 22.00 hours. Stepwise linear multiple regression analyses was used for the statistical analyses. Role ambiguity at baseline and the interaction between role ambiguity and trait rumination contributed to explaining elevations in morning saliva cortisol secretion 3.5 years later (R(2) = 0.045; F = 4.57; p organisational downsizing and restructuring, may contribute to long-term psycho-physiological reactivity. This could expose workers to increased health risks. Therefore, stress management programmes should include the concept of role stress, especially at a time where many work organisations are undergoing significant change. Management should also be made aware of the importance of communicating clear goals, objectives and lines of authority as well as providing sufficient training for those in new job roles.

  15. Morning cortisol secretion in school-age children is related to the sleep pattern of the preceding night.

    Science.gov (United States)

    Lemola, Sakari; Perkinson-Gloor, Nadine; Hagmann-von Arx, Priska; Brand, Serge; Holsboer-Trachsler, Edith; Grob, Alexander; Weber, Peter

    2015-02-01

    Sleep disturbance in childhood is common and a risk factor for poor mental health. Evidence indicates that disturbed sleep is associated with altered hypothalamic-pituitary-adrenal axis (HPAA) activity. Knowledge regarding the association between HPAA-activity and objective sleep measures particularly regarding sleep architecture in school-age children is missing. Sleep-electroencephalography was administered to 113 children aged 6-10 years (including 58 children born very preterm and 55 born at term) during one night at the children's homes and sleep duration, sleep continuity, and sleep architecture were assessed. To assess the cortisol awakening response at the following morning, cortisol secretion was measured at awakening, 10, 20, and 30min later. Regression analyses controlling child age, gender, prematurity status, and the awakening time revealed that morning cortisol secretion was negatively associated with sleep duration and slow wave sleep and positively associated with the relative amount of Stage 2 sleep during the preceding night. In addition, morning cortisol secretion linearly increased with age. In conclusion, associations of sleep disturbance with poor mental health may be confounded with altered HPAA-activity.

  16. Effects of waking time and breakfast intake prior to evaluation of psychomotor performance in the early morning.

    Science.gov (United States)

    Bougard, Clément; Moussay, Sébastien; Gauthier, Antoine; Espié, Stéphane; Davenne, Damien

    2009-02-01

    Many studies conducted in the field of chronobiology report diurnal fluctuation in cognitive and physical performance that occurs in phase with the body temperature circadian rhythm. Waking time and whether or not breakfast is consumed are currently considered to influence the diurnal fluctuation in data collected in the morning at 06:00 h and evening at 18:00 h. Nineteen male subjects participated in four test sessions to examine if wake-up time (04:00 h or 05:00 h) and eating or not eating breakfast influence psychomotor performance capacity at 06:00 h. All four sessions were separated by >/=36 h and were completed in a counterbalanced order. Each test session comprised sign cancellation, Epworth Sleepiness Scale, simple reaction time, and manual dexterity tests. Most of the results indicate that psychomotor performance when evaluated at 06:00 h under each of the four different study situations (two waking times and two breakfast conditions) is not statistically significantly different. Consequently, previous results that documented diurnal fluctuations in morning and evening performance capacities, with test sessions at 06:00 h, are confirmed. Being less efficient in the early morning than in the afternoon potentially exposes people to elevated risk of accident and injury at this time of the day. Prior waking time and/or consumption of a light meal, plus other countermeasures mentioned in the literature, are insufficient to prevent this risk.

  17. Investigation and Analysis of Promotion of Sports Campus on Physical and Mental Health of College Students---Taking Waving Dance in Morning Exercises As An Example%运动校园促进大学生身心健康的调查与分析--以早操开展摆手舞为例

    Institute of Scientific and Technical Information of China (English)

    李海

    2014-01-01

    Using literature, questionnaire, interview and mathematical statistics to investigate and analyze morning situation for students of Hubei University of Arts School of Mechanical and Automotive Engineering. The results show that most students think that a single morning exercise programs, a lack of enthusiasm. Recommendation: Morning increase management body, rich morning exercise program, to carry out traditional sports with national characteristics, stimulate students desire to exercise.%运用文献资料法、问卷调查法、访谈法与数理统计法对湖北文理学院机械与汽车工程学院的全体学生晨练情况进行调查分析。结果显示,大部分学生认为晨练项目单一,缺乏积极性。建议:加大晨练的管理体质、丰富晨练项目,开展具有民族特色的传统体育项目,激发学生的锻炼欲望。

  18. Oxidative stress by peripheral blood mononuclear cells is increased in hypertensives with an extreme-dipper pattern and/or morning surge in blood pressure.

    Science.gov (United States)

    Maeda, Kensaku; Yasunari, Kenichi; Watanabe, Takanori; Nakamura, Munehiro

    2005-09-01

    Because oxidative stress and inflammation are known to play important roles in the pathogenesis of cardiovascular events that occur most frequently in the morning, we studied the association between reactive oxygen species (ROS) formation by polymorphonuclear leukocytes (PMNs) or mononuclear cells (MNCs) and morning blood pressure (BP) rhythm. A total of 31 hypertensives in whom ambulatory BP monitoring was performed participated in this study. They were first divided into three groups according to their nocturnal BP rhythm (non-dippers, dippers and extreme dippers), and then into two groups according to their morning BP change (surge-type and sustained-type). ROS formation by PMNs and MNCs was measured by gated flow cytometry. C-reactive protein and traditional risk factors such as age, gender, body mass index, hemoglobin A1c, and total cholesterol were also measured. ROS formation by MNCs was significantly increased in extreme dippers (vs. dippers, p<0.05, n=11) and in morning BP surge-type hypertensives (vs. sustained-type, p<0.05, n=13). In patients who were both extreme dippers and morning BP surge-types, ROS formation by MNCs was significantly higher than that in other groups. These results suggest that both extreme dippers and morning BP surge-type hypertensives may suffer increased ROS formation by MNCs, and that increased ROS formation by MNCs may underlie morning strokes.

  19. A Geophysical Study in Grand Teton National Park and Vicinity, Teton County, Wyoming: With Sections on Stratigraphy and Structure and Precambrian Rocks

    Science.gov (United States)

    Behrendt, John Charles; Tibbetts, Benton L.; Bonini, William E.; Lavin, Peter M.; Love, J.D.; Reed, John C.

    1968-01-01

    An integrated geophysical study - comprising gravity, seismic refraction, and aeromagnetic surveys - was made of a 4,600-km2 area in Grand Teton National Park and vicinity, Wyoming, for the purpose of obtaining a better understanding of the structural relationships in the region. The Teton range is largely comprised of Precambrian crystalline rocks and layered metasedimentary gneiss, but it also includes granitic gneiss, hornblende-plagioclase gneiss, granodiorite, and pegmatite and diabase dikes. Elsewhere, the sedimentary section is thick. The presence of each system except Silurian provides a chronological history of most structures. Uplift of the Teton-Gros Ventre area began in the Late Cretaceous; most of the uplift occurred after middle Eocene time. Additional uplift of the Teton Range and downfaulting of Jackson Hole began in the late Pliocene and continues to the present. Bouguer anomalies range from -185 mgal over Precambrian rocks of the Teton Range to -240 mgal over low-density Tertiary and Cretaceous sedimentary rocks of Jackson Hole. The Teton fault (at the west edge of Jackson Hole), as shown by steep gravity gradients and seismic-refraction data, trends north-northeast away from the front of the Teton Range in the area of Jackson Lake. The Teton fault either is shallowly inclined in the Jenny Lake area, or it consists of a series of fault steps in the fault zone; it is approximately vertical in the Arizona Creek area. Seismic-refraction data can be fitted well by a three-layer gravity model with velocities of 2.45 km per sec for the Tertiary and Cretaceous rocks above the Cloverly Formation, 3.9 km per sec for the lower Mesozoic rocks, and 6.1 km per sec for the Paleozoic (limestone and dolomite) and Precambrian rocks. Gravity models computed along two seismic profiles are in good agreement (sigma=+- 2 mgal) if density contrasts with the assumed 2.67 g per cm2 Paleozoic and Precambrian rocks are assumed to be -0.35 and -0.10 g per cm2 for the 2

  20. "Social jetlag" in morning-type college students living on campus: implications for physical and psychological well-being.

    Science.gov (United States)

    Lau, Esther Yuet Ying; Wong, Mark Lawrence; Ng, Eddie Chi Wai; Hui, Chi-chiu Harry; Cheung, Shu Fai; Mok, Doris Shui Ying

    2013-08-01

    Although on-campus residence allows easier access to campus facilities, existing studies showed mixed results regarding the relationship between college residence and students' well-being indicators, such as sleep behaviors and mood. There was also a lack of studies investigating the role of chronotype in the relationship between on-campus residence and well-being. In particular, the temporal relationships among these factors were unclear. Hence, this longitudinal study aims to fill in these gaps by first reporting the well-being (measured in terms of mood, sleep, and quality of life) among students living on and off campus across two academic semesters. We explored factors predicting students' dropout in university residences. Although students living on campus differ in their chronotypes, activities in campus residence (if any) are mostly scheduled in the nighttime. We therefore tested if individual differences in chronotype interact with campus residence in affecting well-being. Our final sample consisted of 215 campus residents and 924 off-campus-living students from 10 different universities or colleges in Hong Kong or Macau. Their mean age was 20.2 years (SD=2.3); 6.5% of the participants are female. Participants completed self-reported questionnaires online on their sleep duration, sleep quality, chronotype, mood, and physical and psychological quality of life. Across two academic semesters, we assessed if students living on and off campus differed in our well-being measures after we partialed out the effects of demographic information (including age, sex, family income, and parents' education) and the well-being measures at baseline (T1). The results showed that, campus residents exhibited longer sleep duration, greater sleep efficiency, better sleep quality, and less feeling of stress than off-campus-living students. From one semester to the next, around 10% of campus residents did not continue to live on campus. Logistic regression showed that a morning

  1. Epinephrine preworkout elevation may offset early morning melatonin concentrations to maintain maximal muscular force and power in track athletes.

    Science.gov (United States)

    Kraemer, William J; Boyd, Brittny M; Hooper, David R; Fragala, Maren S; Hatfield, Disa L; Dunn-Lewis, Courtenay; Comstock, Brett A; Szivak, Tunde K; Flanagan, Shawn D; Looney, David P; Newton, Robert U; Vingren, Jakob L; Häkkinen, Keijo; White, Mark T; Volek, Jeff S; Maresh, Carl M

    2014-09-01

    The optimal time of day for training has become an important question for many strength and conditioning specialists, and this study was designed to add some insights into this complex question. The primary purpose of this investigation was to examine physical performance within the temporal context of the relationship between physical performance, epinephrine, and melatonin concentrations in the early morning (0530 hours) and late (1500 hours) afternoon in elite collegiate male track and field athletes (jumpers and sprinters). Subjects had a mean (±SD) age, height, and body mass of 20.4 (±1.6) years, 185.8 (±9.4) cm, and 77.9 (±8.5) kg, respectively. Blood was obtained before each AM and PM testing session. Mean plasma melatonin concentrations were 34.9 ± 22.7 pg·ml and 4.8 ± 3.3 pg·ml for the AM vs. PM trials, respectively, demonstrating a significant (p ≤ 0.05) difference between time points. Mean resting plasma epinephrine concentrations for AM (171.7 ± 33.7 pmol·L) and PM (127.6 ± 47.8 pmol·L) also differed significantly between trails at the different times. In addition, significant differences were observed with respect to foot quickness in the AM (5.14 ± 1.06 seconds) and PM (4.39 ± 0.76 seconds). Mean peak power output for vertical jump power was 5,407.1 ± 1,272.9 W, 5,384.6 ± 888.3 W for AM vs. PM trials, respectively, which were not significantly different. The results of this investigation indicate that time of day did not negatively impact whole body physical performance in trained track athletes but did impact the quality of quickness. Thus in the morning, whole body power performances may be enhanced through adrenergic arousal when melatonin is elevated. However, this was not the case for movements requiring quickness and accuracy of movement. To compensate for the "sleepiness" associated with high concentrations of melatonin, being secreted from the pineal gland representing a continued "sleepiness" effect on the body, early

  2. Human circadian system causes a morning peak in prothrombotic plasminogen activator inhibitor-1 (PAI-1) independent of the sleep/wake cycle.

    Science.gov (United States)

    Scheer, Frank A J L; Shea, Steven A

    2014-01-23

    Serious adverse cardiovascular events peak in the morning, possibly related to increased thrombosis in critical vessels. Plasminogen activator inhibitor-1 (PAI-1), which inhibits fibrinolysis, is a key circulating prothrombotic factor that rises in the morning in humans. We tested whether this morning peak in PAI-1 is caused by the internal circadian system or by behaviors that typically occur in the morning, such as altered posture and physical activity. Twelve healthy adults underwent a 2-week protocol that enabled the distinction of endogenous circadian effects from behavioral and environmental effects. The results demonstrated a robust circadian rhythm in circulating PAI-1 with a peak corresponding to ∼6:30 am. This rhythm in PAI-1 was 8-times larger than changes in PAI-1 induced by standardized behavioral stressors, including head-up tilt and 15-minute cycle exercise. If this large endogenous morning peak in PAI-1 persists in vulnerable individuals, it could help explain the morning peak in adverse cardiovascular events.

  3. Flavoring agents present in a dentifrice can modify volatile sulphur compounds (VSCs) formation in morning bad breath.

    Science.gov (United States)

    Peruzzo, Daiane Cristina; Salvador, Sérgio Luis; Sallum, Antonio Wilson; Nogueira-Filho, Getúlio da Rocha

    2008-01-01

    This study aimed to evaluate the effects of a flavor-containing dentifrice on the formation of volatile sulphur compounds (VSCs) in morning bad breath. A two-step, blinded, crossover, randomized study was carried out in 50 dental students with a healthy periodontium divided into two experimental groups: flavor-containing dentifrice (test) and non-flavor-containing dentifrice (control). The volunteers received the designated dentifrice and a new toothbrush for a 3 X/day brushing regimen for 2 periods of 30 days. A seven-day washout interval was used between the periods. The assessed parameters were: plaque index (PI), gingival index (GI), organoleptic breath scores (ORG), VSC levels (as measured by a portable sulphide monitor) before (H1) and after (H2) cleaning of the tongue, tongue coating (TC) wet weight and BANA test from TC samples. The intra-group analysis showed a decrease in ORG, from 3 to 2, after 30 days for the test group (p flavor also did not interfere in the BANA results between groups (p > 0.05). These findings suggest that a flavor-containing dentifrice seems to prevent VSCs formation in morning bad breath regardless of the amount of TC in periodontally healthy subjects.

  4. Circumnutation and its dependence on the gravity response in rice, morning glory and pea plants: verification by spaceflight experiments

    Science.gov (United States)

    Takahashi, Hideyuki; Kobayashi, Akie; Fujii, Nobuharu; Yano, Sachiko; Shimazu, Toru; Kim, Hyejeong; Tomita, Yuuta; Miyazawa, Yutaka

    Plant organs display helical growth movement known as circumnutation. This movement helps plant organs find suitable environmental cues. The amplitude, period and shape of the circumnutation differ depending on plant species or organs. Although the mechanism for circumnutation is unclear, it has long been argued whether circumnutation is involved with gravitropic response. Previously, we showed that shoots of weeping morning glory (we1 and we2) are impaired in not only the differentiation of endodermis (gravisensing cells) and gravitropic response, but also winding and circumnutation (Kitazawa et al., PNAS 102: 18742-18747, 2005). Here, we report a reduced circumnutation in the shoots of rice and the roots of pea mutants defective in gravitropic response. Coleoptiles of clinorotated rice seedlings and decapped roots of pea seedlings also showed a reduction of their circumnutational movement. These results suggest that circumnutation is tightly related with gravitropic response. In the proposed spaceflight experiments, “Plant Rotation”, we will verify the hypothesis that circumnutation requires gravity response, by using microgravity environment in KIBO module of the International Space Station. We will grow rice and morning glory plants under both muG and 1G conditions on orbit and monitor their growth by a camera. The downlinked images will be analyzed for the measurements of plant growth and nutational movements. This experiment will enable us to answer the question whether circumnutation depends on gravity response or not.

  5. Stress contagion in the classroom? The link between classroom teacher burnout and morning cortisol in elementary school students.

    Science.gov (United States)

    Oberle, Eva; Schonert-Reichl, Kimberly A

    2016-06-01

    The purpose of this study was to explore the link between classroom teachers' burnout levels and students' physiological stress response. Drawing from a stress-contagion framework, we expected higher levels of teacher burnout to be related to elevated cortisol levels in elementary school students (N = 406, 50% female, Mean age = 11.26, SD = .89). Classroom teacher burnout was assessed with the Maslach Burnout Inventory modified for teachers. Salivary cortisol was collected as an indicator of students' hypothalamic-pituitary-adrenal (HPA) functioning. We collected salivary cortisol in children at 9 a.m., 11:30 a.m., and 2 p.m. in the classroom setting. Using Multilevel Modeling, we found that children's morning cortisol levels significantly varied between classrooms (10% variability). Higher levels of classroom teacher burnout significantly predicted the variability in morning cortisol. Teacher burnout reduced the unexplained variability in cortisol at the classroom level to 4.6%. This is the first study to show that teachers' occupational stress is linked to students' physiological stress regulation. We discuss the present findings in the context of potential stress contagion in the classroom, considering empirical and practical relevance. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Elevated morning cortisol is a stratified population-level biomarker for major depression in boys only with high depressive symptoms.

    Science.gov (United States)

    Owens, Matthew; Herbert, Joe; Jones, Peter B; Sahakian, Barbara J; Wilkinson, Paul O; Dunn, Valerie J; Croudace, Timothy J; Goodyer, Ian M

    2014-03-04

    Major depressive disorder (MD) is a debilitating public mental health problem with severe societal and personal costs attached. Around one in six people will suffer from this complex disorder at some point in their lives, which has shown considerable etiological and clinical heterogeneity. Overall there remain no validated biomarkers in the youth population at large that can aid the detection of at-risk groups for depression in general and for boys and young men in particular. Using repeated measurements of two well-known correlates of MD (self-reported current depressive symptoms and early-morning cortisol), we undertook a population-based investigation to ascertain subtypes of adolescents that represent separate longitudinal phenotypes. Subsequently, we tested for differential risks for MD and other mental illnesses and cognitive differences between subtypes. Through the use of latent class analysis, we revealed a high-risk subtype (17% of the sample) demarcated by both high depressive symptoms and elevated cortisol levels. Membership of this class of individuals was associated with increased levels of impaired autobiographical memory recall in both sexes and the greatest likelihood of experiencing MD in boys only. These previously unidentified findings demonstrate at the population level a class of adolescents with a common physiological biomarker specifically for MD in boys and for a mnemonic vulnerability in both sexes. We suggest that the biobehavioral combination of high depressive symptoms and elevated morning cortisol is particularly hazardous for adolescent boys.

  7. Morning and nocturnal serum melatonin rhythm levels in patients with major depressive disorder: an analytical cross-sectional study

    Directory of Open Access Journals (Sweden)

    Shahnaz Khaleghipour

    Full Text Available CONTEXT AND OBJECTIVE: The pineal gland is an adaptive organ that precisely regulates the biological rhythms of melatonin brain hemostasis. Variation in the regulation of melatonin rhythms is a likely cause of depressive disorder. The purpose of this study was to measure serum melatonin levels in patients with major depressive disorder (MDD and normal control subjects. DESIGN AND SETTING: Analytical cross-sectional study at the industrial medical unit of the Iron Smelting Company of Isfahan, Iran. METHODS: The morning and nocturnal serum melatonin levels of patients and controls were measured using the enzyme-linked immunosorbent assay (ELISA method. All data were assessed using variance analysis. RESULTS: The morning and nocturnal serum melatonin levels of depressed and healthy subjects differed (P < 0.05. The nocturnal serum melatonin levels of depressed women were lower than those of depressed men (P < 0.05. CONCLUSIONS: The findings of this study showed that the nocturnal serum melatonin levels in the depressed patients were lower than in the controls. Thus, the peak melatonin phase in the depressed patients was reached with delay. CLINICAL TRIAL REGISTRATION NUMBER: NCT01357083

  8. Morning-evening difference of team-handball-related short-term maximal physical performances in female team handball players.

    Science.gov (United States)

    Mhenni, Thouraya; Michalsik, Lars Bojsen; Mejri, Mohamed Arbi; Yousfi, Narimen; Chaouachi, Anis; Souissi, Nizar; Chamari, Karim

    2017-05-01

    This study investigated the two different time-of-day effect on team-handball-related short-term maximal physical performances. At two different time-of-day, fifteen young female team handball players performed different physical tests: HandGrip (HG) test, Ball-Throwing Velocity (BTV) test, Modified Agility T-test (MAT) and Repeated Shuttle-Sprint and Jump Ability (RSSJA) test. Rating of perceived exertion (RPE) scale was determined following the termination of the last test. Measurements were performed at two separate testing sessions (i.e., in the morning (7:00-8:30 h) and in the early evening (17:00-18:30 h)) in a randomised and counter-balanced setting on non-consecutive days. The results showed that HG (P = 0.0013), BTV (P = 0.0027) and MAT (P handball players, team-handball-related short-term maximal physical performances were better in the afternoon than in the morning.

  9. Effects of waking time and breakfast intake prior to evaluation of physical performance in the early morning.

    Science.gov (United States)

    Bougard, Clement; Bessot, Nicolas; Moussay, Sebastien; Sesboue, Bruno; Gauthier, Antoine

    2009-02-01

    Diurnal variation in both core body temperature and indicators of physical performance are usually observed when measures are taken at 06:00 and 18:00 h. However, differences have been reported between findings in the literature; this may be in some part due to methodological reasons, such as if the experimenter allowed subjects to eat breakfast before the morning 06:00 h session, or even the waking time of subjects. Eleven diurnally active male subjects participated in four test sessions to examine if the time of morning wakening (04:00 or 05:00 h) and eating or not eating breakfast influence body temperature, flexibility, force production, and aerobic performance at 06:00 h. All four sessions were separated by > or = 36 h and were completed in a counterbalanced order. Each test session comprised a sit-and-reach test, an arm maximal voluntary torque evaluation (isometric, concentric at 1.05 rad.s(-1) and at 4.19 rad.s(-1)), and a 10 min all-out cycle ergometer test. Our results indicate the effects of waking time or food intake depend on the parameter tested. Consequently, we advise researchers to take care in experimental design and to at least standardize the time of awakening and consumption of breakfast.

  10. Competency-structured case discussion in the morning meeting: enhancing CanMEDS integration in daily practice

    Directory of Open Access Journals (Sweden)

    Hassan IS

    2015-05-01

    Full Text Available Imad Salah Hassan, Hadi Kuriry, Lina Al Ansari, Ali Al-Khathami, Mohammed Al Qahtani, Thari Al Anazi, Mahfooz Farooqui, Hamdan Al Jahdali Department of Medicine 1443, King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia Abstract: Outcome-focused, competency-based educational curricula have become the norm in residency training programs. The Canadian Medical Education Directives for Specialists (CanMEDS framework is one example of such a curriculum. However, models for incorporating all the competencies in everyday clinical practice have been difficult to accomplish. In this manuscript, a CanMEDS, competency-structured, acute case discussion in a regular morning meeting was undertaken. All the diagnostic and therapeutic interventions were explicitly organized and discussed under their respective CanMEDS competency headings. Post exercise, the majority of residents felt that they were more competent in all the competencies and indicated their willingness to continue having similarly structured acute case discussions in the future. Keywords: CanMEDS roles, residents, morning meeting

  11. Focus on ODA | Gros plan sur l’APD

    Directory of Open Access Journals (Sweden)

    2012-05-01

    Full Text Available Evolution of Selected DAC Members’ ODA, 1990–2010 (in percentage of GNIEvolution de l’APD d’une sélection de pays membres du CAD, 1990-2010 (en pourcentage du RNBSource: OECD, OECD.Stat Extracts, http://stats.oecd.org/Index.aspx.ODA by Donor Country | L’APD par pays donateurDAC Members’ Net ODA, 2010 (in million USDAPD nette des pays membres du CAD, 2010 (en millions USD­DAC Members’ Net ODA, 2010 (in percentage of GNIAPD nette des pays membres du CAD, 2010 (en pourcentage du RNBSource:...

  12. Järgmine on Euroopa eluasemeturg / Daniel Gros

    Index Scriptorium Estoniae

    Gros, Daniel

    2008-01-01

    Ilmunud ka: Den za Dnjom 22. veebr. lk. 26. USA kinnisvarakriis avaldab oma mõju ka Euroopale, kus kinnisvarahinnad on kümnendiga samuti järsult tõusnud. Tõenäoliselt järgneb sellele liialdusele mõningane alahindamine

  13. Zoom on India | Gros plan sur l’Inde

    Directory of Open Access Journals (Sweden)

    2012-05-01

    Full Text Available Indian Energy Production and Consumption (in Million Tonnes of Oil EquivalentProduction et consommation d’énergie en Inde (en millions de tonnes d’équivalent pétroleSource: World Bank, World Bank Development Indicators, 2010.Indian Oil, Gas and Coal Imports (in Million Tonnes of Oil Equivalent, 2008*Importations indiennes de pétrole, de gaz et de charbon (en millions de tonnes d’équivalent pétrole, 2008** 2009 for coal data | 2009 pour les données sur le charbon.Sources: British Petroleum...

  14. The EAGLE Concept-Framework for a Future Land Morning System

    Science.gov (United States)

    Arnold, Stephan; Hezeu, Gerard; Valcarcel Sanz, Nuria

    2016-08-01

    The EAGLE concept embodies a new approach for land monitoring initiatives following an object-oriented approach in landscape modelling. It aims at providing a basis for an integrated European Land Monitoring Framework. Once implemented, the EAGLE concept with its data model and tools can help to harmonize and make comparable different LC/LU classification systems on national and European level. Also, it can provide guidance for mapping initiatives and field campaigns to describe landscape in an application- neutral manner by the descriptive decomposition of the landscape instead of classification. The EAGLE concept ´s target is after all the pan-European dimension, but also can be broadened up to be check on the dimension of global test beds.

  15. Short Blue Light Pulses (30 Min) in the Morning Support a Sleep-Advancing Protocol in a Home Setting.

    Science.gov (United States)

    Geerdink, Moniek; Walbeek, Thijs J; Beersma, Domien G M; Hommes, Vanja; Gordijn, Marijke C M

    2016-10-01

    Many people in our modern civilized society sleep later on free days compared to work days. This discrepancy in sleep timing will lead to so-called 'social jetlag' on work days with negative consequences for performance and health. Light therapy in the morning is often proposed as the most effective method to advance the circadian rhythm and sleep phase. However, most studies focus on direct effects on the circadian system and not on posttreatment effects on sleep phase and sleep integrity. In this placebo-controlled home study we investigated if blue light, rather than amber light therapy, can phase shift the sleep phase along with the circadian rhythm with preservation of sleep integrity and performance. We selected 42 participants who suffered from 'social jetlag' on workdays. Participants were randomly assigned to either high-intensity blue light exposure or amber light exposure (placebo) with similar photopic illuminance. The protocol consisted of 14 baseline days without sleep restrictions, 9 treatment days with either 30-min blue light pulses or 30-min amber light pulses in the morning along with a sleep advancing scheme and 7 posttreatment days without sleep restrictions. Melatonin samples were taken at days 1, 7, 14 (baseline), day 23 (effect treatment), and day 30 (posttreatment). Light exposure was recorded continuously. Sleep was monitored through actigraphy. Performance was measured with a reaction time task. As expected, the phase advance of the melatonin rhythm from day 14 to day 23 was significantly larger in the blue light exposure group, compared to the amber light group (84 min ± 51 (SD) and 48 min ± 47 (SD) respectively; t36 = 2.23, p light group compared to slightly later in the amber light group (-21 min ± 33 (SD) and +12 min ± 33 (SD) respectively; F1,35 = 9.20, p light group compared to the blue light group during sleep in the treatment period (F1,32 = 4.40, p light treatment (F1,13 = 17.1, p light condition (F1

  16. Influence of chronotype on responses to a standardized, self-paced walking task in the morning vs afternoon: a pilot study.

    Science.gov (United States)

    Vitale, Jacopo A; Calogiuri, Giovanna; Weydahl, Andi

    2013-06-01

    The response to sub-maximal physical activity performed in the morning and late afternoon by individuals with different chronotypes was investigated. 22 participants filled out the Morningness-Eveningness Questionnaire and underwent a self-paced walking task that consisted of walking from the top to the bottom of a hill and back three times (1,836 meters, with a slope of 14.16%). The task was repeated twice: late afternoon (16:30) and early morning (08:30). Walking speed (time for completion in seconds), heart rate, and perceived exertion were measured during each task, with overall results given as a general descriptive analysis. Preliminary findings suggest that chronotype is likely to influence the responses to exercise, mostly with evening-types seeming at a disadvantage when performing a physical task in the morning. Individuals can be classified by circadian typology or chronotype, which is the propensity to be a morning-type, evening-type, or neither-type. The circadian typology, commonly referred to as being a morning person or an evening person or somewhere in between, is involved not only in the expression of physiological rhythms, but also in habits and lifestyles, such as sleeping patterns (Park, Matsumoto, Seo, & Shinkoda, 1999) that emerge especially during adolescence (Park, Matsumoto, Seo, Kang, & Nagashima, 2002) and remain throughout adult life (Koukkari & Sothern, 2006).

  17. Comparison between the effect of 6 weeks of morning or evening aerobic exercise on appetite and anthropometric indices: a randomized controlled trial.

    Science.gov (United States)

    Alizadeh, Z; Younespour, S; Rajabian Tabesh, M; Haghravan, S

    2017-03-26

    Several studies have shown that exercise is directly related to creating negative energy balance and changes in appetite. However, few studies have examined the effect of exercise time during the day on these factors. The aim of the present study was to demonstrate the effect of 6 weeks of morning and evening aerobic exercise on appetite and anthropometric indices. A total of 48 overweight females were recruited to this clinical trial. By the time of exercise, they were divided into two groups (morning or evening) and performed 6 weeks of exercise with a target heart rate on the ventilatory threshold. Appetite change, calorie intake and anthropometric indices were assessed. Consistent changes in appetite scores were not found during the 6 weeks (P > 0.05). Calorie consumption of the morning group decreased significantly more than that of the evening group (P = 0.02) during the 6 weeks. In addition, significant changes in body weight, body mass index, abdominal skin fold thickness and abdominal circumference were seen in the morning group. It appears that moderate- to high-intensity aerobic exercise in the morning could be considered a more effective programme than evening exercise on appetite control, calorie intake and weight loss in inactive overweight women. However, the limitations of the study, such as short-term duration, should be noticed.

  18. Ionospheric conductances and currents of a morning sector auroral arc from Swarm-A electric and magnetic field measurements

    Science.gov (United States)

    Juusola, L.; Archer, W. E.; Kauristie, K.; Burchill, J. K.; Vanhamäki, H.; Aikio, A. T.

    2016-11-01

    We show the first ionospheric Hall and Pedersen conductances derived from Swarm magnetic and electric field measurements during a crossing of a morning sector auroral arc. Only Swarm-A was used, with assumptions of negligible azimuthal gradients and vanishing eastward electric field. We find upward field-aligned current, enhanced Hall and Pedersen conductances, and relatively weak electric field coincident with the arc. Poleward of the arc, the field-aligned current was downward, conductances lower, and the electric field enhanced. The arc was embedded in a westward electrojet, immediately equatorward of the peak current density. The equatorward portion of the electrojet could thus be considered conductance dominant and the poleward portion electric field dominant. Although the electric field measured by Swarm was intense, resulting in conductances lower than those typically reported, comparable electric fields have been observed earlier. These results demonstrate how Swarm data can significantly contribute to our understanding of the ionospheric electrodynamics.

  19. Normal Morning MCH Levels and No Association with REM or NREM Sleep Parameters in Narcolepsy Type 1 and Type 2

    DEFF Research Database (Denmark)

    Schrölkamp, Maren; Jennum, Poul J; Gammeltoft, Steen;

    2017-01-01

    STUDY OBJECTIVES: Other than hypocretin-1 (HCRT-1) deficiency in narcolepsy type 1 (NT1), the neurochemical imbalance of NT1 and narcolepsy type 2 (NT2) with normal HCRT-1 levels is largely unknown. The neuropeptide melanin-concentrating hormone (MCH) is mainly secreted during sleep and is involved...... in rapid eye movement (REM) and nonrapid eye movement (NREM) sleep regulation. Hypocretin neurons reciprocally interact with MCH neurons. We hypothesized that altered MCH secretion contributes to the symptoms and sleep abnormalities of narcolepsy and that this is reflected in morning cerebrospinal fluid...... (CSF) MCH levels, in contrast to previously reported normal evening/afternoon levels. METHODS: Lumbar CSF and plasma were collected from 07:00 to 10:00 from 57 patients with narcolepsy (subtypes: 47 NT1; 10 NT2) diagnosed according to International Classification of Sleep Disorders, Third Edition...

  20. A Sorrow Halved? A Daily Diary Study on Talking About Experienced Workplace Incivility and Next-Morning Negative Affect.

    Science.gov (United States)

    Tremmel, Stephanie; Sonnentag, Sabine

    2017-08-31

    Incivility by coworkers and customers can have detrimental consequences for employees' affective well-being at work. However, little is known about whether incivility also impairs employees' affect at home and how long these negative effects may last. In this diary study, we examine whether incivility by coworkers and customers is related to next-morning negative affect via negative affect at the end of the workday and at bedtime, and investigate different modes of social sharing (i.e., conversations about experienced mistreatment) as day-level moderators of this relationship. Daily diary data collected over 10 workdays (N = 113 employees) revealed that coworker incivility was indirectly related to bedtime negative affect via negative affect at the end of the workday, and customer incivility was indirectly related to next-morning negative affect via negative affect at the end of the workday and at bedtime. Although we found no moderating effect for conversations in an affective sharing mode (i.e., conversation partners provide comfort and consolation), the relationship between workplace incivility and employees' negative affect was buffered by conversations in a cognitive sharing mode (i.e., conversation partners suggest alternative explanations or reappraisal of uncivil behavior). In line with social sharing theory, our results suggest that talking about experienced mistreatment can, under specific circumstances, offset the negative relationship of uncivil coworker and customer behavior and employees' negative affect. This study advances current research on workplace incivility by studying negative affect 3 times a day and thus sheds light on the mechanism connecting workplace incivility and employees' affective well-being at home. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  1. Baseline morning cortisol level as a predictor of pituitary-adrenal reserve: a comparison across three assays.

    Science.gov (United States)

    Sbardella, Emilia; Isidori, Andrea M; Woods, Conor P; Argese, Nicola; Tomlinson, Jeremy W; Shine, Brian; Jafar-Mohammadi, Bahram; Grossman, Ashley B

    2017-02-01

    The short ACTH stimulation test (250 μg) is the dynamic test most frequently used to assess adrenal function. It is possible that a single basal cortisol could be used to predict the dynamic response, but research has been hampered by the use of different assays and thresholds. To propose a morning baseline cortisol criterion of three of the most commonly used modern cortisol immunoassays - Advia Centaur (Siemens), Architect (Abbott) and the Roche Modular System (Roche) - that could predict adrenal sufficiency. Observational, retrospective cross-sectional study at two centres. Retrospective analysis of the results of 1019 Short Synacthen tests (SSTs) with the Advia Centaur, 449 SSTs with the Architect and 2050 SSTs with the Roche Modular System assay. Serum cortisol levels were measured prior to injection of 250 μg Synacthen and after 30 min. Overall, we were able to collate data from a total of 3518 SSTs in 3571 patients. Using receiver-operator curve analysis, baseline cortisol levels for predicting passing the SST with 100% specificity were 358 nmol/l for Siemens, 336 nmol/l for Abbott and 506 nmol/l for Roche. Utilizing these criteria, 589, 158 and 578 SSTs, respectively, for Siemens, Abbott and Roche immunoassays could have been avoided. We have defined assay-specific morning cortisol levels that are able to predict the integrity of the hypothalamo-pituitary-adrenal axis. We propose that this represents a valid tool for the initial assessment of adrenal function and has the potential to obviate the need for dynamic testing in a significant number of patients. © 2016 John Wiley & Sons Ltd.

  2. The efficacy of fluticasone furoate administered in the morning or evening is comparable in patients with persistent asthma.

    Science.gov (United States)

    Kempsford, R D; Bal, J; Baines, A; Renaux, J; Ravindranath, R; Thomas, P S

    2016-03-01

    The inhaled corticosteroid fluticasone furoate (FF) is efficacious as a once-daily treatment for the management of asthma. Asthma is associated with circadian changes, with worsening lung function at night. We compared the efficacy of once-daily FF in the morning or evening for the treatment of asthma. Adults with persistent bronchial asthma were enrolled into this randomised, repeat-dose, double-blind, double-dummy, placebo-controlled, three-way crossover study. After a 14-day run-in period, patients received either: FF 100 μg in the morning (AM); FF 100 μg in the evening (PM); or placebo, via the ELLIPTA(®) dry powder inhaler. Patients received all three treatments (14 ± 2 day duration) separated by a 14- to 21-day washout period. The primary endpoint was 24-h weighted mean forced expiratory volume in 1 s (FEV1) measured at the end of each 14-day treatment. A total of 28 patients aged between 19 and 67 years were randomised and 21 (75%) completed all three study arms. Once-daily administration of FF 100 μg resulted in an increased 24-hour weighted mean FEV1; differences between the adjusted means for AM and PM FF dosing versus placebo were 0.077 L (90% confidence interval [CI]: 0.001, 0.152) and 0.105 L (90% CI: 0.029, 0.180), respectively (adjusted mean difference: -0.028 L [90% CI: -0.102, 0.045]). AM or PM doses had comparable incidences of adverse events (AEs; 18/23 versus 18/24, respectively), no serious AEs occurred. AM and PM doses of once-daily FF 100 μg produced comparable improvements in lung function relative to placebo. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  3. Effects of time-of-day on neuromuscular function in untrained men: Specific responses of high morning performers and high evening performers.

    Science.gov (United States)

    Küüsmaa, Maria; Sedliak, Milan; Häkkinen, Keijo

    2015-01-01

    It has been clearly established that maximal force varies during the day in human muscles but the exact mechanisms behind the diurnal rhythms are still not fully clarified. Therefore, the aim of this study was to examine the diurnal rhythms in maximal isometric force production in a large group of participants and also by separating the high morning performance types (n = 8) and the high evening performance types (n = 19) from the neutral types (n = 45) based on their actual maximal isometric force levels. Measurements were performed in the morning (7:26 h ± 63 min) and in the evening (17:57 h ± 74 min) for maximal bilateral isometric leg press force (MVCLP) together with myoelectric activity (EMGLP), maximal unilateral isometric knee extension force (MVCKE) and maximal voluntary activation level (VA%) during maximal unilateral isometric knee extension force (MVCVA) together with myoelectric activity (EMGVA). In addition, venous blood samples were drawn four times a day and serum testosterone and cortisol concentrations were analyzed. None of the participants belonged to the extreme morning or evening chronotype according to the Munich Chronotype Questionnaire. In the total group of participants, MVCLP and MVCKE were 4.4 ± 12.9% (p variation. The high morning performance types showed lower force values in the evening compared to the morning for MVCLP (10.8 ± 9.1%; p variation was observed for MVCVA and VA%. The high evening performance types showed higher force values in the evening for MVCLP (16.1 ± 15.9%; p variations. EMGLP and EMGVA did not show significant diurnal fluctuations in any group. Serum testosterone and cortisol concentrations showed normal daily rhythms with higher values observed in the morning in all of the groups (p explain the diurnal fluctuations in maximal strength performance, but peripheral mechanisms were also possibly involved.

  4. The effect of two weeks morning and afternoon special training program on performance and plasma levels of IL-17 and cortisol in wushu athletes

    Directory of Open Access Journals (Sweden)

    B ghayeblo

    2016-02-01

    Full Text Available Background & Aims: Recent evidences (knowing the effects of time on physiological variables show that the human body undergoes a lot of changes during the day and the night and has a special ability in each hour. Competition in the morning Confronts athletes with the problem of susceptibility to infection and inflammation. The purpose of this study was to examine The effect of two weeks morning and afternoon special training program on performance and plasma levels of IL-17 and cortisol in boy wushu athletes Materials and Methods: Fourteen sanda boy athletes were purposefully selected and after Bruce and  rast tests run, divided into the two Similar groups morning-time training group (N = 7, training time 9 a.m. and evening-time training group (N=7, training time 18 pm . The Subjects were trained for two weeks (6 session in each week according to an Sanda sport specific training program. Values of peak anaerobic power, average anaerobic power, minimum anaerobic power and fatigue index measured with Field  rast test. To determine the amount of plasma IL-17 and cortisol , the participants’ blood samples was taken In the fasting state three times, 24 h before the first training session in baseline status and Immediately after tests at 9 am and 48 h after the last training session immediately after tests performance at 9 a.m. Data were analyzed using repeated measures, independent-samplesT-test, ,paired- samplesT-test  and Covariance. Results: The results showed that there were significant differences between the amounts of plasma IL-17 of the two groups after two weeks(P0.05. Conclusion: It seems likely transition training time to the morning, 2 weeks before the competition in the morning, decrease inflammatory factors such as IL-17 in sanda boys. Therefore appears that two weeks transition training time from evening to morning can increase the safety of athletes immune during the competition.

  5. Sleep and Alertness Management III: Effects of a Nap and Hypnotics on Performance During the Late Evening, Night and Early Morning in Marmosets

    Science.gov (United States)

    2006-11-01

    hypnotics on performance Info-DenV@tno.nl during the late evening, night and early morning in marmosets Date November 2006 Author(s) Dr. I.H.C.I.M...so-called post-nap hangovers. In this study, the marmoset monkey model was validated as a model for testing the effects of drugs on performance during...evening, night and early morning missions was tested. It was proven that the homeostasis in marmoset monkeys after sleep deprivation is similar to the

  6. Nation/non-nation

    DEFF Research Database (Denmark)

    Sonnichsen, André; Gad, Ulrik Pram

    2008-01-01

    Is nationality the only way of organizing political community? Given the ubiquity of the national principle, one might think so. But, in practice, the national principle is constantly challenged by what can be termed non-national identities. This article looks at manners in which such deviating...

  7. Nationalism in Stateless Nations

    DEFF Research Database (Denmark)

    Thomsen, Robert Chr.

    previously independent countries, are excellent examples of this. Building on theories of national identity-formation and nationalism, it traces the development of cultural and political nationalism, and changing images of the national self. With a focus on important fomenting factors and actors...... - intellectuals, political parties and the media - the book combines historical, sociological, political and media studies analyses in an interdisciplinary investigation, providing a comprehensive account of the waxing and waning of nationalism....

  8. Association between glycemic control and morning blood surge with vascular endothelial dysfunction in type 2 diabetes mellitus patients

    Directory of Open Access Journals (Sweden)

    Rama Kumari Nuthalapati

    2016-01-01

    Full Text Available Objective: Morning blood pressure surge (MBPS is an independent predictor of cardiovascular events. However, little is known about the association between glycemic control and MBPS, and its effect on vascular injury in patients with type 2 diabetes mellitus (T2DM. The current study examined the association between glycemic control and MBPS and the involvement of MBPS in the development of vascular dysfunction in T2DM patients. Materials and Methods: One hundred and twenty-two consecutive T2DM outpatients from the Department of Cardiology and Endocrinology were enrolled in this study. We did MBPS in T2DM patients, 85 (male (69.7% patients and 37 (female patients (30.3%; mean age 60.1 ± 9.39; (n = 122 using 24 h ambulatory blood pressure monitoring and assessed vascular function by brachial artery flow-mediated dilation (FMD and nitroglycerin-mediated dilation (NMD. Results: The correlation between MBPS and various clinical variables were examined by single regression analysis in all subjects. MBPS showed significant and positive correlation with pulse rate (P = 0.01, fasting blood sugar (P = 0.002, and postprandial blood sugar (P = 0.05. To further confirm the association of insulin resistance (IR with MBPS in T2DM patients, we examined the correlation between homeostasis model assessment-IR (HOMA-IR, an established marker of IR and MBPS in diabetic (DM patients who were not taking insulin no significant association with MBPS in T2DM patients (P = 0.41, angiotensin-converting enzyme/angiotensin receptor blocker (P = 0.07. We examined the relationship between MBPS and vascular injury by measuring endothelium-dependent FMD and endothelium-independent NMD in T2DM patients. Among the various traditional risk factors for atherosclerosis such as DM duration (P = 0.04, platelet reactivity (P = 0.04 and morning surge (P = 0.002 emerged as significant factors. HOMA-IR was a negative correlation with FMD. Conclusions: The current study demonstrated that

  9. Comparison of a morning polypill, evening polypill and individual pills on LDL-cholesterol, ambulatory blood pressure and adherence in high-risk patients; a randomized crossover trial

    NARCIS (Netherlands)

    Lafeber, M.; Grobbee, D. E.; Schrover, I. M.; Thom, S.; Webster, R.; Rodgers, A.; Visseren, F. L. J.; Bots, M. L.; Spiering, W.

    2015-01-01

    Aims: Cardiovascular polypills are a novel strategy in the prevention of cardiovascular disease. Based on considerations about the effectiveness, the individual pills of a polypill are taken at different times of the day. This study aimed therefore to compare the use of a polypill in the morning, in

  10. The Growing Trend of Reading Movements in Japan: Animacion a la Lectura, Ten-Minutes Reading in the Morning, and Reading Aloud by Parents.

    Science.gov (United States)

    Adachi, Sachiko

    This study examines the growing trend of reading movements in Japan and their origins. There are three main movements: Animacion a la Lectura; Ten-Minutes Reading in the Morning; and Reading Aloud by Parents in schools. This paper reports on the three movements from a review of the literature, personal observations, and practice. The paper…

  11. Morning nutrition and executive function processes in preadolescents: gender variations in phasic modulation of frontal eeg theta activity during a go/ no-go task

    Science.gov (United States)

    Frontal EEG theta activity has been related to executive functions (i.e., goal-directed behavior such as inhibition and flexibility of action). We studied the effects of morning nutritional status on frontal theta-executive function relationships using stimulus-locked responses [event-related increa...

  12. Morning nutrition and executive function processes in preadolescents: modulation of frontal event-related theta, beta and gamma EEG oscillations during a go/ no-go task

    Science.gov (United States)

    Executive functions (i.e., goal-directed behavior such as inhibition and flexibility of action) have been linked to frontal brain regions and to covariations in oscillatory brain activity, e.g., theta and gamma activity. We studied the effects of morning nutritional status on executive function rel...

  13. Monday Morning: A Magazine for Language Teachers in China = Lundi Matin: Revue pour professeurs de langues en Chine, 1985-1992.

    Science.gov (United States)

    Monday Morning, 1992

    1992-01-01

    This document consists of all six issues of the bilingual (English and French) periodical "Monday Morning" published from its inception in 1985 through 1992. This publication was developed by the Canada/China Language Training Centre (C/CLTC), a language teaching enterprise that provides French or English language training to Chinese technicians…

  14. The perfect time to be stressed: a differential modulation of human memory by stress applied in the morning or in the afternoon.

    Science.gov (United States)

    Maheu, Françoise S; Collicutt, Patrick; Kornik, Rachel; Moszkowski, Robin; Lupien, Sonia J

    2005-12-01

    We measured the effects of a stressful experience on memory for emotionally arousing and neutral material learned after exposure to a stressor which induces a significant increase in corticosteroid stress hormones. Because memory performance can be influenced by circadian changes in corticosteroid levels, subjects were tested either in the morning or in the afternoon. Nineteen healthy men (9 in the morning group and 10 in the afternoon group) were submitted to a psychological stress task before viewing a story composed of emotionally negative and neutral segments, while another 20 healthy males (10 in the morning group and 10 in the afternoon group) viewed the story without being exposed to the psychological stressor. Salivary cortisol levels were measured before and after the stressor. Memory performance was assessed by a one week post learning delayed recall. Results show that stress-induced increases in salivary cortisol levels impaired delayed free recall of emotionally arousing material in the morning group, but not in the afternoon group. There was no effect of stress on memory for neutral material. Altogether, these findings suggest that stressing participants in the morning, at a time of high circulating levels of corticosteroids, over stimulated the corticosteroid receptors in the brain, impairing declarative memory for emotionally arousing material unrelated to the stressor. These findings suggest that the experimental context, i.e., time of day at which the experiment occurs, the nature of the to-be-remembered material (remembering the stressful event itself or material unrelated to the stressor) and the valence of the to-be-remembered material (emotionally arousing vs. neutral), modulates the effects of stress on human declarative memory.

  15. Morning sector drift-bounce resonance driven ULF waves observed in artificially-induced HF radar backscatter

    Directory of Open Access Journals (Sweden)

    L. J. Baddeley

    Full Text Available HF radar backscatter, which has been artificially-induced by a high power RF facility such as the EISCAT heater at Tromsø, has provided coherent radar ionospheric electric field data of unprecedented temporal resolution and accuracy. Here such data are used to investigate ULF wave processes observed by both the CUTLASS HF radars and the EISCAT UHF radar. Data from the SP-UK-OUCH experiment have revealed small-scale (high azimuthal wave number, m -45 waves, predominantly in the morning sector, thought to be brought about by the drift-bounce resonance processes. Conjugate observations from the Polar CAM-MICE instrument indicate the presence of a non-Maxwellian ion distribution function. Further statistical analysis has been undertaken, using the Polar TIMAS instrument, to reveal the prevalence and magnitude of the non-Maxwellian energetic particle populations thought to be responsible for generating these wave types.

    Key words. Ionosphere (active experiments; wave-particle interactions Magnetospheric physics (MHD waves and instabilities

  16. Saturday Morning Television Advertisements Aired on English and Spanish Language Networks along the Texas-Mexico Border.

    Science.gov (United States)

    Barroso, Cristina S; Rodriguez, Dianeth; Camacho, Perla L

    2011-10-18

    OBJECTIVES: The aim of this content analysis study is to characterize the TV advertisements aired to an at-risk child population along the Texas-Mexico border. METHODS: We characterized the early Saturday morning TV advertisements aired by three broadcast network categories (U.S. English language, U.S. Spanish language, and Mexican Spanish language) in Spring 2010. The number, type (food related vs. non-food related), target audience, and persuasion tactics used were recorded. Advertised foods, based on nutrition content, were categorized as meeting or not meeting current dietary guidelines. RESULTS: Most commercials were non-food related (82.7%, 397 of 480). The majority of the prepared foods (e.g., cereals, snacks, and drinks) advertised did not meet the current U.S. Dietary Guidelines. Additionally, nutrition content information was not available for many of the foods advertised on the Mexican Spanish language broadcast network category. CONCLUSIONS: For U.S. children at risk for obesity along the Texas-Mexico border exposure to TV food advertisements may result in the continuation of sedentary behavior as well as an increased consumption of foods of poor nutritional quality. An international regulatory effort to monitor and enforce the reduction of child-oriented food advertising is needed.

  17. Saturday Morning Television Advertisements Aired on English and Spanish Language Networks along the Texas-Mexico Border

    Science.gov (United States)

    Barroso, Cristina S.; Rodriguez, Dianeth; Camacho, Perla L.

    2011-01-01

    Objectives The aim of this content analysis study is to characterize the TV advertisements aired to an at-risk child population along the Texas-Mexico border. Methods We characterized the early Saturday morning TV advertisements aired by three broadcast network categories (U.S. English language, U.S. Spanish language, and Mexican Spanish language) in Spring 2010. The number, type (food related vs. non-food related), target audience, and persuasion tactics used were recorded. Advertised foods, based on nutrition content, were categorized as meeting or not meeting current dietary guidelines. Results Most commercials were non-food related (82.7%, 397 of 480). The majority of the prepared foods (e.g., cereals, snacks, and drinks) advertised did not meet the current U.S. Dietary Guidelines. Additionally, nutrition content information was not available for many of the foods advertised on the Mexican Spanish language broadcast network category. Conclusions For U.S. children at risk for obesity along the Texas-Mexico border exposure to TV food advertisements may result in the continuation of sedentary behavior as well as an increased consumption of foods of poor nutritional quality. An international regulatory effort to monitor and enforce the reduction of child-oriented food advertising is needed. PMID:22209760

  18. LANGUAGE APPRAISAL ON ATTITUDINAL SYSTEMS FOR EXPLORING IDEOLOGY IN DEATH PENALTY IN SYDNEY MORNING HERALD AND HERALD SUN EDITORIALS

    Directory of Open Access Journals (Sweden)

    Rosyida Ekawati

    2015-10-01

    Full Text Available This article deals with the ideology represented by newspaper editorials. It is from the idea that every language use is never neutral and not ideology-free. Language is used to convey meanings in a broad sense. There are meanings related to the opinions through the language as resources of evaluation. Editorial is one practice of language use full of opinions towards a certain issue on people or things. Sydney Morning Herald and Herald Sun are used as both Australian newspaper posit themselves as the high-rank newspaper in terms of circulation and online accessed. This article tries to uncover the ideologies represented by both newspaper editorials concerning death penalty of Bali Nine executed in Indonesia. Attitudinal perspective proposed by Martin and White (2005 in term of affect, judgement, and appreciation of language appraisal is used to explore ideology in the newspaper. From appraisal analysis, it is found that Indonesia dominantly appraised in negative There is no positive appreciation for Indonesia in both newspaper editorials. judgement while Australia is portrayed in positive view for the issue of death penalty in Indonesia.

  19. Mozart in the Morning.

    Science.gov (United States)

    Gaustad, Susan

    1983-01-01

    A year-long music instruction unit introduces students to information about the lives of nine great composers of the classics and to their works. Each month a different composer is featured. No special training for teachers is necessary. (PP)

  20. Mozart in the Morning.

    Science.gov (United States)

    Gaustad, Susan

    1983-01-01

    A year-long music instruction unit introduces students to information about the lives of nine great composers of the classics and to their works. Each month a different composer is featured. No special training for teachers is necessary. (PP)

  1. Performance and nitrogen use efficiency in mid-lactation dairy cows fed timothy cut in the afternoon or morning.

    Science.gov (United States)

    Brito, A F; Tremblay, G F; Bertrand, A; Castonguay, Y; Bélanger, G; Michaud, R; Lafrenière, C; Martineau, R; Berthiaume, R

    2016-07-01

    Shifting cutting from morning to afternoon has been shown to increase the concentration of nonstructural carbohydrates in forages. We hypothesized that, compared with a total mixed ration containing timothy baleage and silage cut in the morning (a.m.-cut TIM), a total mixed ration containing timothy baleage and silage cut in the afternoon (p.m.-cut TIM) would improve animal performance and N use efficiency in mid-lactation Holstein cows due to enhanced supply of ruminal fermentable energy. The objective of this study was to compare the effects of p.m.- versus a.m.-cut TIM on milk yield, concentrations and yields of milk components, ruminal metabolism, and plasma concentrations of AA in mid-lactation Holstein cows. Ten (6 ruminally cannulated) primiparous cows averaging 139±13 d in milk and 550±56 kg of body weight, and 6 (2 ruminally cannulated) multiparous cows averaging 128±11 d in milk and 632±57 kg of body weight at the beginning of the experiment, were used in a crossover design. Each period lasted 21 d with 14 d for diet adaptation and 7 d for data and sample collection. The concentration of nonstructural carbohydrates (water-soluble carbohydrates plus starch) was numerically greater in the p.m.- versus the a.m.-cut TIM and averaged 13.2±1.06% and 12.2±1.13%, respectively. Treatment × parity effects were observed for milk urea N, feed efficiency, and milk N efficiency, whereas parity effects were observed for nutrient intake, milk yield, and plasma concentration of several essential and nonessential AA. Intakes of dry matter (19.3 versus 18.6 kg/d) and nonstructural carbohydrates (2.56 versus 2.31 kg/d), and yields of 4% fat-corrected milk (23.1 versus 22.2 kg/d), energy-corrected milk (25.0 versus 24.1 kg/d), milk fat (0.91 versus 0.88 kg/d), and milk protein (0.77 versus 0.73 kg/d) were all greatest with feeding p.m.-cut TIM. Milk yield (23.5 versus 22.7 kg/d) tended to increase in cows fed p.m.-cut TIM. The ruminal fermentation profiles and plasma

  2. Self- and rater-assessed effectiveness of "thinking-aloud" and "regular" morning report to intensify young physicians' clinical skills.

    Science.gov (United States)

    Hsu, Hui-Chi; Lee, Fa-Yauh; Yang, Ying-Ying; Tsao, Yen-Po; Lee, Wen-Shin; Chuang, Chiao-Lin; Chang, Ching-Chih; Huang, Chia-Chang; Huang, Chin-Chou; Ho, Shung-Tai

    2015-09-01

    This study compared the effects of the "thinking aloud" (TA) morning report (MR), which is characterized by sequential and interactive case discussion by all participants, with "regular" MR for clinical skill training of young physicians. Between February 2011 and February 2014, young physicians [including postgraduate year-1 (PGY1) residents, interns, and clerks) from our hospital were sequentially enrolled and followed for 3 months. The self- and rater-assessed educational values of two MR models for building up clinical skills of young physicians were compared. The junior (intern and clerk) attendees had higher self-assessed educational values scores and reported post-training application frequency of skills trained by TA MR compared with the senior (PGY1 resident) attendees. Higher average and percentage of increased overall rater-assessed OSCE scores were noted among the regular MR senior attendees and TA MR junior attendees than in their corresponding control groups (regular MR junior attendees and TA MR senior attendees). Interestingly, regular MRs provided additional beneficial effects for establishing the "professionalism, consulting skills and organization efficiency" aspects of clinical skills of senior/junior attendees. Moreover, senior and junior attendees benefited the most by participating in seven sessions of regular MR and TA MR each month, respectively. TA MR effectively trains junior attendees in basic clinical skills, whereas regular MR enhances senior attendees' "work reports, professionalism, organizational efficiency, skills in dealing with controversial and professional issues." Undoubtedly, all elements of the two MR models should be integrated together to ensure patient safety and good discipline among young physicians. Copyright © 2015. Published by Elsevier Taiwan.

  3. Evening use of light-emitting eReaders negatively affects sleep, circadian timing, and next-morning alertness

    Science.gov (United States)

    Chang, Anne-Marie; Aeschbach, Daniel; Duffy, Jeanne F.; Czeisler, Charles A.

    2015-01-01

    In the past 50 y, there has been a decline in average sleep duration and quality, with adverse consequences on general health. A representative survey of 1,508 American adults recently revealed that 90% of Americans used some type of electronics at least a few nights per week within 1 h before bedtime. Mounting evidence from countries around the world shows the negative impact of such technology use on sleep. This negative impact on sleep may be due to the short-wavelength–enriched light emitted by these electronic devices, given that artificial-light exposure has been shown experimentally to produce alerting effects, suppress melatonin, and phase-shift the biological clock. A few reports have shown that these devices suppress melatonin levels, but little is known about the effects on circadian phase or the following sleep episode, exposing a substantial gap in our knowledge of how this increasingly popular technology affects sleep. Here we compare the biological effects of reading an electronic book on a light-emitting device (LE-eBook) with reading a printed book in the hours before bedtime. Participants reading an LE-eBook took longer to fall asleep and had reduced evening sleepiness, reduced melatonin secretion, later timing of their circadian clock, and reduced next-morning alertness than when reading a printed book. These results demonstrate that evening exposure to an LE-eBook phase-delays the circadian clock, acutely suppresses melatonin, and has important implications for understanding the impact of such technologies on sleep, performance, health, and safety. PMID:25535358

  4. How private vehicle use increases ambient air pollution concentrations at schools during the morning drop-off of children

    Science.gov (United States)

    Adams, Matthew D.; Requia, Weeberb J.

    2017-09-01

    A child's exposure to environmental pollutants can have life-long health effects. Thus it is critical to understand the potential exposure pathways. In this paper, we examine the increase in ambient PM2.5 concentrations at schools from private vehicle use for dropping children off at school. In North America, students are commonly driven to school in a private vehicle. Additionally, students walk or cycle, or take a school bus. Our vehicle surveys recorded between 23 and 116 personal vehicles at 25 schools, where enrolment ranged from 160 to 765 students. We fit a linear regression model to predict the number of vehicles at schools we did not observe within our study area, which explained 57% of the variation in our surveys. A microsimulation traffic model was created for each of the 86 schools we studied. Outputs from the traffic model were used to determine the emissions generated at each school. PM2.5 emissions varied from 0.14 to 6.38 g. Lastly, we dispersed the emissions produced by private vehicles dropping off students, which are emissions generated by unnecessary trips because students further than walking distance are provided transportation by the school board. At the drop-off location in front of the school, we found ambient concentration increases of at least 5 μg/m3, 10 μg/m3, 25 μg/m3 and 50 μg/m3 during 16.8%, 7.6%, 2.0% and 0.5% of the mornings, respectively. This research was conducted in a medium-sized North American city and should allow transferability to similar cities. We conclude that the use of private vehicles can significantly increase local concentrations, regardless of background conditions.

  5. Wearing blue-blockers in the morning could improve sleep of workers on a permanent night schedule: a pilot study.

    Science.gov (United States)

    Sasseville, Alexandre; Benhaberou-Brun, Dalila; Fontaine, Charlotte; Charon, Marie-Claude; Hebert, Marc

    2009-07-01

    Night shiftworkers often complain of disturbed sleep during the day. This could be partly caused by morning sunlight exposure during the commute home, which tends to maintain the circadian clock on a daytime rhythm. The circadian clock is most sensitive to the blue portion of the visible spectrum, so our aim was to determine if blocking short wavelengths of light below 540 nm could improve daytime sleep quality and nighttime vigilance of night shiftworkers. Eight permanent night shiftworkers (32-56 yrs of age) of Quebec City's Canada Post distribution center were evaluated during summertime, and twenty others (24-55 yrs of age) during fall and winter. Timing, efficacy, and fragmentation of daytime sleep were analyzed over four weeks by a wrist activity monitor, and subjective vigilance was additionally assessed at the end of the night shift in the fall-winter group. The first two weeks served as baseline and the remaining two as experimental weeks when workers had to wear blue-blockers glasses, either just before leaving the workplace at the end of their shift (summer group) or 2 h before the end of the night shift (fall-winter group). They all had to wear the glasses when outside during the day until 16:00 h. When wearing the glasses, workers slept, on average +/-SD, 32+/-29 and 34+/-60 more min/day, increased their sleep efficacy by 1.95+/-2.17% and 4.56+/-6.1%, and lowered their sleep fragmentation by 1.74+/-1.36% and 4.22+/-9.16% in the summer and fall-winter group, respectively. Subjective vigilance also generally improved on Fridays in the fall-winter group. Blue-blockers seem to improve daytime sleep of permanent night-shift workers.

  6. Evening use of light-emitting eReaders negatively affects sleep, circadian timing, and next-morning alertness.

    Science.gov (United States)

    Chang, Anne-Marie; Aeschbach, Daniel; Duffy, Jeanne F; Czeisler, Charles A

    2015-01-27

    In the past 50 y, there has been a decline in average sleep duration and quality, with adverse consequences on general health. A representative survey of 1,508 American adults recently revealed that 90% of Americans used some type of electronics at least a few nights per week within 1 h before bedtime. Mounting evidence from countries around the world shows the negative impact of such technology use on sleep. This negative impact on sleep may be due to the short-wavelength-enriched light emitted by these electronic devices, given that artificial-light exposure has been shown experimentally to produce alerting effects, suppress melatonin, and phase-shift the biological clock. A few reports have shown that these devices suppress melatonin levels, but little is known about the effects on circadian phase or the following sleep episode, exposing a substantial gap in our knowledge of how this increasingly popular technology affects sleep. Here we compare the biological effects of reading an electronic book on a light-emitting device (LE-eBook) with reading a printed book in the hours before bedtime. Participants reading an LE-eBook took longer to fall asleep and had reduced evening sleepiness, reduced melatonin secretion, later timing of their circadian clock, and reduced next-morning alertness than when reading a printed book. These results demonstrate that evening exposure to an LE-eBook phase-delays the circadian clock, acutely suppresses melatonin, and has important implications for understanding the impact of such technologies on sleep, performance, health, and safety.

  7. Changes in blood lipid in elderly population following morning exercise%健康老年人晨练活动后的血脂变化

    Institute of Scientific and Technical Information of China (English)

    陈静侬

    2002-01-01

    Objective To investigate mechanisms involving the effect of exercise on blood lipid in healthy elders.Method Healthy elders aged >60 years were included in study group,In control group,age,sex and body mathched persons were included.Blood lipid was evaluated for study group before and 3 months after morning exercise.Morning exercise consisted of walking with constant velocity(60~ 80 m/min) for 40~ 50 minutes,five times a week.Level of blood lipid in study group was compared with that of control group.Result TC,TG were significantly reduced and HE increased as compared with control group 3 months after exercise(P< 0.05).No changes occurred immediately and 20 hours after first exercise(P< 0.05).Conclusion Exercise can decrease TC,TG and raise HDL-C,which is beneficial to prevention of cerebrovascular and cardiovascular diseases in healthy elders.

  8. Increased calorie intake at a specific mid-morning meal and increased intake of soft drinks are strongly associated with obesity in Mexican rural women.

    Science.gov (United States)

    Caamaño, María C; Gutierrez, Jessica; García, Olga P; Ronquillo, Dolores; Martinez, Guadalupe; Rosado, Jorge L

    2015-01-01

    The study investigated the dietary habits and foods that are associated with obesity in women from a rural area in Mexico. Anthropometry and body fat were measured in 580 women. Participants answered a socioeconomic and a food-frequency questionnaire; a subsample (n = 80) also answered three 24-hour-recall questionnaires. Results showed that obese women consumed more soft drinks and fat than did overweight and normal-weight women. Women who consumed more energy during a mid-morning meal had higher BMI. A strategy to decrease the prevalence of obesity in rural areas could be to encourage limiting the consumption of soft drinks and eliminating or reducing caloric intake at a mid-morning meal.

  9. Carbohydrates from Sources with a Higher Glycemic Index during Adolescence: Is Evening Rather than Morning Intake Relevant for Risk Markers of Type 2 Diabetes in Young Adulthood?

    Directory of Open Access Journals (Sweden)

    Tanja Diederichs

    2017-06-01

    Full Text Available Background: This study investigated whether glycemic index (GI or glycemic load (GL of morning or evening intake and morning or evening carbohydrate intake from low- or higher-GI food sources (low-GI-CHO, higher-GI-CHO during adolescence are relevant for risk markers of type 2 diabetes in young adulthood. Methods: Analyses included DOrtmund Nutritional and Anthropometric Longitudinally Designed (DONALD study participants who had provided at least two 3-day weighed dietary records (median: 7 records during adolescence and one blood sample in young adulthood. Using multivariable linear regression analyses, estimated morning and evening GI, GL, low-GI-CHO (GI < 55 and higher-GI-CHO (GI ≥ 55 were related to insulin sensitivity (N = 252, hepatic steatosis index (HSI, fatty liver index (FLI (both N = 253, and a pro-inflammatory-score (N = 249. Results: Morning intakes during adolescence were not associated with any of the adult risk markers. A higher evening GI during adolescence was related to an increased HSI in young adulthood (p = 0.003. A higher consumption of higher-GI-CHO in the evening was associated with lower insulin sensitivity (p = 0.046 and an increased HSI (p = 0.006, while a higher evening intake of low-GI-CHO was related to a lower HSI (p = 0.009. Evening intakes were not related to FLI or the pro-inflammatory-score (all p > 0.1. Conclusion: Avoidance of large amounts of carbohydrates from higher-GI sources in the evening should be considered in preventive strategies to reduce the risk of type 2 diabetes in adulthood.

  10. Highway driving in the elderly the morning after bedtime use of hypnotics: a comparison between temazepam 20 mg, zopiclone 7.5 mg, and placebo.

    Science.gov (United States)

    Leufkens, Tim R M; Vermeeren, Annemiek

    2009-10-01

    A major problem related to hypnotic drug use is residual sedation the morning after bedtime administration. This constitutes a particular safety hazard for patients who have to drive a car the next morning. Information on the severity of residual effects is mainly derived from studies conducted with young healthy volunteers. However, most users of hypnotics are older people who may be more sensitive to drug effects. The aim of this study was to evaluate the residual effects the morning after evening doses of temazepam 20 mg and zopiclone 7.5 mg on driving performance in healthy elderly drivers. Eighteen healthy elderly drivers (10 females and 8 males; mean age, 64.3 years) participated in a double-blind, 3-way crossover study. Treatments were single oral doses of temazepam 20 mg, zopiclone 7.5 mg, and placebo administered at bedtime. Subjects performed a standardized highway driving test between 10 and 11 hours after hypnotic intake. Before and after the driving test, cognitive performance was assessed. Driving performance did not differ between temazepam and placebo but was significantly impaired after zopiclone 7.5 mg (P hypnotics. Temazepam 20 mg is unlikely to impair driving 10 hours or more after bedtime administration in healthy elderly aged 75 years or younger. Zopiclone 7.5 mg moderately impairs driving in the elderly at least until 11 hours after administration. The magnitude of impairing effects in the elderly was comparable with those found previously in younger volunteers.

  11. Investigation on Current Situation of Middle School Students’ Morning Exercise in Shantou City%汕头市中学生晨练现状调查研究

    Institute of Scientific and Technical Information of China (English)

    王腊姣; 卢刚

    2014-01-01

    This paper made an investigation and study of the current situation about students ’ morning exercise in 11 middle schools in Shantou city by means of questionnaire survey , comparative analysis and mathematical statis-tics, analyzed the secondary students ’ perspective, preference, ways, motivation, place and content, restrictive factors and common misconceptions of morning exercises , discussed the positive and negative factors for the devel-opment of students ’ morning exercises in secondary schools in Shantou , and finally proposed the corresponding countermeasure and suggestion .%本文通过问卷调查法、比较分析法及数理统计法等对汕头市11所学校的中学生晨练现状进行了调查研究,分析了中学生晨练的认知态度、情绪体验、组织形式、动机类型、晨练地点与内容、晨练的制约因素以及晨练中的常见误区,探讨了汕头市中学生晨练活动发展的积极因素和不利因素,并提出相应的有益于中学生晨练活动开展的对策和建议。

  12. Comparison of acute skin reaction following morning versus late afternoon radiotherapy in patients with breast cancer who have undergone curative surgical resection.

    Science.gov (United States)

    Noh, Jae Myoung; Choi, Doo Ho; Park, Hyojung; Huh, Seung Jae; Park, Won; Seol, Seung Won; Jeong, Bae Kwon; Nam, Seok Jin; Lee, Jeong Eon; Kil, Won-Ho

    2014-05-01

    We investigated the relationship between the time of radiotherapy (RT) and treatment outcomes in breast cancer. Patients with pathologic T1-2N0-1 breast cancer who received adjuvant RT in the morning (before 10:00 AM) or late afternoon (after 3:00 PM) were eligible for inclusion in this study. We retrospectively compared the clinicopathologic characteristics, acute skin reaction, and survival outcomes according to the time of RT. The median follow-up duration was 83 months (range, 10-131 months). From the 395 eligible patients, 190 (48.1%) and 205 (51.9%) patients were classified into the morning RT group and the afternoon RT group, respectively. The clinicopathologic characteristics were relatively well balanced between the treatment groups, except for pathologic N-stage (P = 0.0409). Grade 2 or higher acute skin reaction according to the Radiation Therapy Oncology Group criteria was observed in 39 (9.9%) patients, with a higher frequency in the afternoon RT group than the morning RT group (13.7% vs 5.8%, respectively; P = 0.0088). There was no difference in the failure patterns or survival outcomes between the treatment groups. RT in late afternoon was associated with increased Grade 2 or more skin reaction after RT for breast cancer patients, but treatment outcomes did not differ according to the time of RT. Individualized considerations for treatment should be taken into account to reduce the risk of skin reactions.

  13. Morphological and physiological responses of morning glory (Ipomoea lacunosa L.) grown in a lead- and chelate-amended soil.

    Science.gov (United States)

    Kambhampati, Murty S; Begonia, Gregorio B; Begonia, Maria F T; Bufford, Yolanda

    2005-08-01

    Lead (Pb) is one of the most toxic metals in the environment and may cause drastic morphological and physiological deformities in Ipomoea lacunosa. The goal of this research was to evaluate some morphological and physiological responses of morning glory grown on a Pb- and chelate-amended soil. Soil samples were analyzed, at Mississippi State University Soil Laboratory, for physico-chemical parameters, such as soil texture (73% sand, 23% silt, 4.4% clay), organic matter (6.24 +/- 0.60%), and pH (7.95 +/- 0.03), to establish soil conditions at the beginning of the experiments. Five EDTA (ethylenediaminetetraacetic acid) concentrations (0, 0.1, 0.5, 1, 5mM) and four lead (0, 500, 1000, 2000mg/L) treatments were arranged in factorial in a Randomized Complete Block (RCB) design with five replications. Duncan's multiple comparison range test showed that the mean difference values of stomatal density were significant between 500 and 1000mg/L Pb and between 1000 and 2000mg/L Pb. Two way ANOVA (at 1% level) indicated that interaction between Pb and EDTA had a significant effect on the stomatal density and photosynthetic rates, and at 5% level Pb had a significant effect on chlorophyll concentrations. Lowest concentrations of chlorophyll were recorded at 2000mg/L Pb and 5mM EDTA and exhibited a decreasing trend specifically in the ranges of 1000 and 2000mg/L Pb and 1.0 and 5.0mM EDTA. Duncan's multiple comparison range test confirmed that mean differences between the control treatment vs. 2000mg/L Pb, and 500mg/L vs. 2000mg/L Pb were significantly different atp>0.05. There was a decrease in leaf net photosynthetic rate with increasing concentrations of Pb from 0 to 2000mg/L. In conclusion, I. lacunosa L. plants were grown to maturity in all treatments with no significant and/or apparent morphological disorders, which indicated that this species might be highly tolerant even at 2000mg/L Pb concentrations in the soil.

  14. A cross-sectional observational study to investigate daily symptom variability, effects of symptom on morning activities and therapeutic expectations of patients and physicians in COPD-SUNRISE study.

    Science.gov (United States)

    Kuyucu, Tülin; Güçlü, Salih Zeki; Saylan, Bengü; Demir, Cahit; Senol, Tuncer; Güner, Serdar; Koyuncu, Ejder; Ozen, Ferit; Oztürk, Sezai; Cangül, Zeki; Ağanoğlu, Semih; Ozkaya, Sevket; Ocak, Sevilay Ciçek; Akkurt, Hüseyin; Intepe, Yavuz Selim; Bayrak, Merve Gülcan; Güler, Tuncay; Bekçi, Taha Tahir; Soyyiğit, Sadan; Seyfettin, Salim; Kula, Ozhan; Akbay, Makbule Ozlem; Büyükgöze, Bengü; Asal, Gökhan; Başlilar, Seyma; Oztürk, Osman

    2011-01-01

    Chronic obstructive pulmonary disease (COPD) is a lung disease characterized with limitation of airflow that is not completely reversible, progressive deterioration of airways and systemic inflammation. This study has been planned to determine daily symptom variability of patients, expectations of patient and physicians from treatment and patient profiles. A total of 514 patients with COPD from 25 centers were included in this national, multicenter, cross-sectional observational study. Data regarding demographic features, concomitant diseases, history and treatment of COPD and expectations of patients and physicians were all obtained in a single visit. Mean [standard deviation (SD)] age of the patients was 64.1 (9.5) years; age range was 41-92 years, 50% of the patients were younger than 65 years and 91% were males. Educational level of the patients was at least primary school in 80.2%; and 54.3% (30.4%) of the patients had at least one concomitant disease, particularly a cardiovascular disease. Mean (SD) duration of having COPD was 5.4 (4.6) years. The majority of patients were at moderate (43.2%) and severe (35.0%) COPD stages and one or more exacerbations per year was determined in 71%. Inhaled beta-2 agonists (84.2%), inhaled steroids (76.3%) and inhaled long-acting anti-cholinergics (70.0%) were the most commonly used medications. Dyspnea (99.0%), sputum production (92.8%) and wheezing (90.5%) were the most common symptoms, and symptom variability for dyspnea (41.1%), sputum production (61.0%) and cough (53.5%) were seen the most in the morning hours (psocks/shoes (point of effect: 4.3) and showering/bathing (point of effect: 4.2) by COPD. Major treatment expectations of patients were greater symptomatic relief (82.3%) and greater mobility (70.0%), faster symptomatic relief (61.1%) and improvement in morning activities (59.3%); while major treatment expectations of physicians included increased quality of life (100.0%) and decreased morbidity (96.0%). Quitting

  15. Temporal variability of pyrethroid metabolite levels in bedtime, morning, and 24-h urine samples for 50 adults in North Carolina.

    Science.gov (United States)

    Morgan, Marsha K; Sobus, Jon R; Barr, Dana Boyd; Croghan, Carry W; Chen, Fu-Lin; Walker, Richard; Alston, Lillian; Andersen, Erik; Clifton, Matthew S

    2016-01-01

    Pyrethroid insecticides are widely used to control insects in both agricultural and residential settings worldwide. Few data are available on the temporal variability of pyrethroid metabolites in the urine of non-occupationally exposed adults. In this work, we describe the study design and sampling methodology for the Pilot Study to Estimate Human Exposures to Pyrethroids using an Exposure Reconstruction Approach (Ex-R study). Two major objectives were to quantify the concentrations of several pyrethroid metabolites in bedtime, first morning void (FMV), and 24-h urine samples as concentration (wet weight), specific-gravity (SG) corrected, creatinine (CR) corrected, and excretion rate values for 50 Ex-R adults over a six-week monitoring period and to determine if these correction approaches for urine dilution reduced the variability of the biomarker levels. The Ex-R study was conducted at the United States Environmental Protection Agency's Human Studies Facility in Chapel Hill, North Carolina USA and at participants' homes within a 40-mile radius of this facility. Recruitment of participants and field activities occurred between October 2009 and May 2011. Participants, ages 19-50 years old, provided daily food, activity, and pesticide-use diaries and collected their own urine samples (bedtime, FMV, and 24-h) during weeks 1, 2, and 6 of a six-week monitoring period. A total of 2503 urine samples were collected from the study participants. These samples were analyzed for the pyrethroid metabolites 3-phenoxybenzoic acid (3-PBA), cis/trans-3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropane carboxylic acid (cis/trans-DCCA), and 2-methyl-3-phenylbenzoic acid (MPA) using high performance liquid chromatography/tandem mass spectrometry. Only 3-PBA was frequently detected (>50%) in the adult urine samples. Median urinary 3-PBA levels were 0.88 ng/mL, 0.96 ng/mL-SG, 1.04 ng/mg, and 1.04 ng/min for concentration, SG-corrected, CR-corrected, and excretion rate values, respectively

  16. Morning and evening behavior in children and adolescents treated with atomoxetine once daily for Attention-Deficit/Hyperactivity Disorder (ADHD: Findings from two 24-week, open-label studies

    Directory of Open Access Journals (Sweden)

    Schacht Alexander

    2009-02-01

    Full Text Available Abstract Background The impact of once daily atomoxetine treatment on symptoms in children and adolescents with ADHD may vary over the day. In order to capture such variations, two studies were undertaken in children and adolescents with ADHD using two instruments that capture morning and evening behavior and ADHD-related difficulties over the day. This secondary measure analysis builds on two primary analyses that were conducted separately for children and adolescents and also published separately. Methods In two open-label studies, ADHD patients aged 6–17 years (n = 421, received atomoxetine in the morning (target-dose 0.5–1.2 mg/kg/day for up to 24 weeks. Morning and evening behavior was assessed using the investigator-rated Weekly Rating of Evening and Morning Behavior (WREMB-R scale. ADHD-related difficulties at various times of the day (morning, during school, during homework, evening were assessed using the Global Impression of Perceived Difficulties (GIPD scale, rated by patients, parents and physicians. Data from both studies were combined for this secondary measure analysis. Results Both WREMB-R subscores decreased significantly over time, the evening subscore from 13.7 (95% CI 13.2;14.2 at baseline to 8.0 (7.4;8.5 at week 2, the morning subscore from 4.3 (4.0;4.5 to 2.4 (2.2;2.6. Scores then remained stable until week 24. All GIPD items improved correspondingly. At all times of the day, patients rated ADHD-related difficulties as less severe than parents and physicians. Conclusion These findings from two open-label studies suggest that morning and evening behavior and ADHD-related difficulties in the mornings and evenings improve over time with once daily atomoxetine treatment.

  17. Antidepressant Utilization and Suicide in Europe : An Ecological Multi-National Study

    NARCIS (Netherlands)

    Gusmao, Ricardo; Quintao, Sonia; McDaid, David; Arensman, Ella; Van Audenhove, Chantal; Coffey, Claire; Vaernik, Airi; Vaernik, Peeter; Coyne, James; Hegerl, Ulrich

    2013-01-01

    Background: Research concerning the association between use of antidepressants and incidence of suicide has yielded inconsistent results and is the subject of considerable controversy. The first aim is to describe trends in the use of antidepressants and rates of suicide in Europe, adjusted for gros

  18. Effects of oil pollution at Kuwait's Greater Al-Burgan oil field on the timing of morning emergence, basking and foraging behaviors by the sand lizard Acanthodactylus scutellatus.

    Science.gov (United States)

    Al-Hashem, M Abdulla; Brain, P F; Omar, S Ahmad

    2008-02-15

    An attempt was made to study the effects of oil pollution in a desert location (the Greater Al-Burgan oil fields, an area damaged in the second Gulf War) in Kuwait on the behaviour of the Sand lizard A. scutellatus. Polluted sites with apparently different degrees of contamination (namely tar mat, soot and clear sites) were compared with control areas outside this region. Between 2002 and 2003, ten lizards (5 of each sex) on each polluted and each control site were observed in the field at a time of the year when they were highly active. Air, substrate and burrow temperatures were recorded and lizards were monitored for their morning emergence times, as well as their basking and foraging activities. The present study confirmed that the morning emergence times and the basking behavior varied in sand lizards among the different pollution site categories. Physical changes in the tar mat sites caused the substrate temperatures in these locations to rise more quickly in the morning in response to solar gain than was the case in the other sites. This gives lizards in these locations the opportunity to emerge earlier and to start eating more quickly, giving them an energetic advantage (perhaps, in turn, influencing their rates of growth and fecundity). The clear sites had the next earliest emergence and were the next hottest but it is difficult to account for this in terms of the physical characteristics of this site. The basking times were clearly shorter on the dark soot and tar mat sites that appeared to have higher solar gain than control or clear sites. There did not appear to be any obvious differences in foraging activity of lizards in the different locations. It appears that some aspects of simple behaviour in these lizards provides a reliable, noninvasive indices for assessing oil pollution in desert locations. The precise impact of these changes in these reptiles on their long-term viability needs to be evaluated.

  19. Significant concentrations of nitryl chloride sustained in the morning: investigations of the causes and impacts on ozone production in a polluted region of northern China

    Science.gov (United States)

    Tham, Yee Jun; Wang, Zhe; Li, Qinyi; Yun, Hui; Wang, Weihao; Wang, Xinfeng; Xue, Likun; Lu, Keding; Ma, Nan; Bohn, Birger; Li, Xin; Kecorius, Simonas; Größ, Johannes; Shao, Min; Wiedensohler, Alfred; Zhang, Yuanhang; Wang, Tao

    2016-12-01

    Nitryl chloride (ClNO2) is a dominant source of chlorine radical in polluted environment, and can significantly affect the atmospheric oxidative chemistry. However, the abundance of ClNO2 and its exact role are not fully understood under different environmental conditions. During the summer of 2014, we deployed a chemical ionization mass spectrometer to measure ClNO2 and dinitrogen pentoxide (N2O5) at a rural site in the polluted North China Plain. Elevated mixing ratios of ClNO2 (> 350 pptv) were observed at most of the nights with low levels of N2O5 (layer at night followed by downward mixing after breakup of the nocturnal inversion layer in the morning. We estimated that ˜ 1.7-4.0 ppbv of ClNO2 would exist in the residual layer in order to maintain the observed morning ClNO2 peaks at the surface site. Observation-based box model analysis show that photolysis of ClNO2 produced chlorine radical with a rate up to 1.12 ppbv h-1, accounting for 10-30 % of primary ROx production in the morning hours. The perturbation in total radical production leads to an increase of integrated daytime net ozone production by 3 % (4.3 ppbv) on average, and with a larger increase of 13 % (11 ppbv) in megacity outflow that was characterized with higher ClNO2 and a relatively lower oxygenated hydrocarbon (OVOC) to non-methane hydrocarbon (NMHC) ratio.

  20. Eight-month test-retest agreement in morning salivary cortisol, self- and parent-rated anxiety in boys with an Autism Spectrum Disorder.

    Science.gov (United States)

    Sharpley, Christopher F; Bitsika, Vicki; Agnew, Linda L; Andronicos, Nicholas M

    2015-11-01

    The agreement over time in morning salivary cortisol concentrations and also self- and parent-rated anxiety was investigated in a sample of 16 boys with an ASD. Cortisol and anxiety data were collected eight months apart. Results indicated that there were significant correlations between each pair of measures from the two occasions, suggesting that cortisol concentrations and anxiety did not vary much at all over that time, challenging the assumption that cortisol needs to be measured over multiple days to obtain reliable data from children with an ASD. Implications for research into the ways these children respond to chronic stressors are discussed.

  1. 长治市服务行业晨操开展的调查研究%Investigation on Morning Exercise Development of Service Industry in Changzhi City

    Institute of Scientific and Technical Information of China (English)

    李明

    2014-01-01

    本文通过文献资料法、访谈法、问卷调查法、数理统计法,对长治市服务行业晨操开展的现状进行调查分析。针对存在问题,提出相关的发展对策及建议,以期为我市服务行业晨操活动的健康发展提供有益参考,进而促进晨操活动在我市服务行业更加科学、广泛地开展。%Through using the method of literature review , interview, questionnaire and mathematical statistics , this paper makes investigation on morning exercise development of service industry in Changzhi city .Based on ex-isting problem, some suggestions and development measurements are put forward .The main purpose is to provide the benefit reference for morning exercise development of service industry in Changzhi city and promote the development more scientifically and widely.

  2. Effect of discontinuing morning dose of antihypertensive for renal transplant surgery on haemodynamic and early graft functioning: A prospective, double-blind, randomised study

    Science.gov (United States)

    Kumar, Vinod; Arya, Virendra Kumar; Sondekoppam, Rakesh V; Arora, Suman; Minz, Mukut; Garg, Rakesh; Gupta, Nishkarsh

    2017-01-01

    Background and Aims: Antihypertensive drugs are continued until the day of renal transplant surgery. These are associated with increased incidence of hypotension and bradycardia. Hence, this study was designed to evaluate perioperative haemodynamic and early graft functioning in renal recipients with discontinuation of antihypertensive drugs on the morning of surgery. Methods: This prospective, randomised, double-blind study recruited 120 patients. Group 1 patients received placebo tablet while Group 2 patients received usual antihypertensive drugs on the day of surgery. Perioperative haemodynamics and time for reinstitution of antihypertensives were the primary outcome measures. The secondary outcome measures were need for inotropic support and graft function. Perioperative haemodynamics were analysed using ANOVA and Student's t-tests with Bonferroni correction. Fischer's exact test was used for analysis. Results: Systolic blood pressure (SBP) declined, which was more in Group 2. Forty-one patients developed significant hypotension; a correlation was found between the maximum observed hypotension and number of antihypertensive medications (P = 0.003). Four cases had slow graft function (one in Group 1 and three in Group 2). Twenty-eight patients in Group 2 required mephentermine boluses to maintain their SBP compared to 13 patients in Group 1 (P drugs can be omitted on the morning of surgery without any haemodynamic fluctuations and graft function in controlled hypertensive end-stage renal disease renal transplant patients receiving a combined epidural and general anaesthesia.

  3. Nationalism in Stateless Nations

    DEFF Research Database (Denmark)

    Thomsen, Robert Chr.

    democracies need not, as argued by theories of 'classic' nationalist movements, strive for full independence. In fact, nationalist movements are adapting to circumstances by becoming autonomist rather than separatist, pragmatic rather than dogmatic, and the book illustrates how Scotland and Newfoundland, both...... - intellectuals, political parties and the media - the book combines historical, sociological, political and media studies analyses in an interdisciplinary investigation, providing a comprehensive account of the waxing and waning of nationalism....

  4. Scotland: Nation without Nationalism?

    Directory of Open Access Journals (Sweden)

    Ya. I. Maltsev

    2015-01-01

    Full Text Available In the period before 1990s two concepts were used to describe the Scottish political development: “Nation without nationalism” and “The stateless nation”. After the devolution of 1998 and electoral achievements of SNP neither of these constructions can properly characterize the processes, undergoing in Scotland. The forming of new alignment of political powers in Scotland is not yet finished, but so far its development leads to the emergence of political configuration separated from that of All-British, with regard to extreme weakening of “big” parties in Scotland. 

  5. Effect of integrated yoga therapy on pain, morning stiffness and anxiety in osteoarthritis of the knee joint: A randomized control study

    Directory of Open Access Journals (Sweden)

    John Ebnezar

    2012-01-01

    Full Text Available Aim: To study the effect of integrated yoga on pain, morning stiffness and anxiety in osteoarthritis of knees. Materials and Methods: Two hundred and fifty participants with OA knees (35-80 years were randomly assigned to yoga or control group. Both groups had transcutaneous electrical stimulation and ultrasound treatment followed by intervention (40 min for two weeks with follow up for three months. The integrated yoga consisted of yogic loosening and strengthening practices, asanas, relaxation, pranayama and meditation. The control group had physiotherapy exercises. Assessments were done on 15 th (post 1 and 90 th day (post 2. Results: Resting pain (numerical rating scale reduced better (P<0.001, Mann-Whitney U test in yoga group (post 1=33.6% and post 2=71.8% than control group (post 1=13.4% and post 2=37.5%. Morning stiffness decreased more (P<0.001 in yoga (post 1=68.6% and post 2=98.1% than control group (post 1=38.6% and post 2=71.6%. State anxiety (STAI-1 reduced (P<0.001 by 35.5% (post 1 and 58.4% (post 2 in the yoga group and 15.6% (post 1 and 38.8% (post 2 in the control group; trait anxiety (STAI 2 reduced (P<0.001 better (post 1=34.6% and post 2=57.10% in yoga than control group (post 1=14.12% and post 2=34.73%. Systolic blood pressure reduced (P<0.001 better in yoga group (post 1=−7.93% and post 2=−15.7% than the control group (post 1=−1.8% and post 2=−3.8%. Diastolic blood pressure reduced (P<0.001 better in yoga group (post 1=−7.6% and post 2=−16.4% than the control group (post 1=−2.1% and post 2=−5.0%. Pulse rate reduced (P<0.001 better in yoga group (post 1=−8.41% and post 2=−12.4% than the control group (post 1=−5.1% and post 2=−7.1%. Conclusion: Integrated approach of yoga therapy is better than physiotherapy exercises as an adjunct to transcutaneous electrical stimulation and ultrasound treatment in reducing pain, morning stiffness, state and trait anxiety, blood pressure and pulse rate in patients

  6. 优质护理服务中落实晨间护理的管理方法与体会%Methods and experiences of management about the implementation of morning care in high quality nursing service

    Institute of Scientific and Technical Information of China (English)

    林蓉金; 饶柳妹

    2013-01-01

    目的 探讨落实晨间护理有效的管理措施.方法 制订晨间护理质量评分表,护士按照评分表质量要求实施晨间护理,对晨间护理实施三级质量控制.结果 提高了护理质量和患者满意度(P<0.01).结论 运用晨间护理质量评分表管理有助于夯实基础护理,提高护理质量.%Objective To explore effective management measures for morning care. Methods The measures included formulation of morning nursing quality assessment scale, implementation of morning care according to the quality requirements, and implementation of three level quality control to morning care. Result The quality of care and patient satisfaction were improved (P < 0. 01). Conclusion The application of the morning care quality assessment scale in management can be conducive to the implementation of basic nursing,and improve the quality of nursing care.

  7. Recurrent nocturnal hypoglycaemia as a cause of morning fatigue in treated Addison's disease--favourable response to dietary management: a case report.

    Science.gov (United States)

    Petersen, Kristina S; Rushworth, R Louise; Clifton, Peter M; Torpy, David J

    2015-10-24

    Addison's disease, or primary adrenal insufficiency, is often associated with reduced well-being and fatigue despite use of currently recommended adrenal hormone replacement. Hypoglycaemia is a known manifestation of glucocorticoid deficiency, but is generally considered rare in adults and not relevant to troubling ongoing symptoms in patients with Addison's disease. A 43 year old woman with a three year history of Addison's disease complained of severe morning fatigue and headaches, despite standard glucocorticoid replacement therapy in the form of thrice daily hydrocortisone and mineralocorticoid replacement with fludrocortisone. Alternative glucocorticoid replacement regimens and the addition of dehydroepiandrosterone replacement therapy had no effect. Nocturnal hypoglycaemia was suspected and a 4-day continuous glucose monitor system (CGMS) revealed hypoglycaemia (interstitial glucose Addison's disease is unknown, but it may be that investigation for hypoglycaemia and treatment, where necessary, could assist some sufferers to achieve improved wellbeing. A systematic study of this phenomenon in Addison's disease is required.

  8. Fever of unknown origin (FUO) due to miliary BCG: The diagnostic importance of morning temperature spikes and highly elevated ferritin levels.

    Science.gov (United States)

    Cunha, Burke A; Apostolopoulou, Anna; Gian, John

    Fever of unknown origin (FUO) is defined as prolonged fever of >101 °F for at least 3 weeks that remains undiagnosed after a focused inpatient or outpatient workup. One of the most elusive FUO diagnoses is miliary tuberculosis (TB) which typically has few/no localizing signs/symptoms. Since the introduction of intravesicular Bacille Calmette-Guerin (BCG) treatment for bladder carcinoma, miliary BCG has only rarely been reported as a cause of FUO. As with miliary TB, there are few/no clues to suspect miliary BCG. We present an interesting case of FUO due to miliary BCG without any localizing signs, i.e., no lung, liver or prostate involvement. The only clues to the diagnosis of this FUO due to disseminated BCG were morning temperature spikes and otherwise unexplained highly elevated ferritin levels. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. Early morning salivary cortisol and cortisone, and adrenal responses to a simplified low-dose short Synacthen test in children with asthma.

    Science.gov (United States)

    Blair, Joanne; Lancaster, Gillian; Titman, Andrew; Peak, Matthew; Newlands, Paul; Collingwood, Catherine; Chesters, Christine; Moorcroft, Teresa; Wallin, Naomi; Hawcutt, Daniel; Gardner, Christopher; Didi, Mohammed; Lacy, David; Couriel, Jonathan

    2014-03-01

    To examine serum cortisol responses to a simplified low-dose short Synacthen test (LDSST) in children treated with inhaled corticosteroids (ICS) for asthma and to compare these to early morning salivary cortisol (EMSC) and cortisone (EMSCn) levels. Early morning salivary cortisol and EMSCn samples were collected for three consecutive days. On day three, Synacthen 500 ng/1·73 m(2) was administered intravenously. Samples were collected at 0, 15, 25, 35 min. A total of 269 subjects (160 M: 109 F), median (range) age 10·0 (5·1-15·2) years were studied. Peak cortisol in the LDSST was <500 nmol/l in 101 subjects (37·5%) and <350 nmol/l in 12 subjects (4·5%). Basal cortisol correlated with peak cortisol: r = 0·55, (95% CI: 0·46, 0·63, P < 0·0001). Time at which peak cortisol concentration was achieved was significantly related to the value of peak cortisol (P < 0·0001), with higher cortisol peaks occurring later in the test and lower cortisol peaks occurring earlier. EMSC and EMSCn had no predictive value for the identification of patients with a peak cortisol <500 nmol/l. EMSCn was superior to EMSC in identifying patients with a peak cortisol <350 nmol/l: a minimum EMSCn cut-off value of 12·5 nmol/l gave a negative predictive value of 99·2% and positive predictive value of 30·1%. Our data illustrate that basal measures of cortisol are likely to be of value in screening populations for patients at greatest risk of adrenal crisis. EMSCn shows promise as a screening tool for the identification of patients with severe adrenal insufficiency. © 2013 John Wiley & Sons Ltd.

  10. Neural reactivity to visual food stimuli is reduced in some areas of the brain during evening hours compared to morning hours: an fMRI study in women.

    Science.gov (United States)

    Masterson, Travis D; Kirwan, C Brock; Davidson, Lance E; LeCheminant, James D

    2016-03-01

    The extent that neural responsiveness to visual food stimuli is influenced by time of day is not well examined. Using a crossover design, 15 healthy women were scanned using fMRI while presented with low- and high-energy pictures of food, once in the morning (6:30-8:30 am) and once in the evening (5:00-7:00 pm). Diets were identical on both days of the fMRI scans and were verified using weighed food records. Visual analog scales were used to record subjective perception of hunger and preoccupation with food prior to each fMRI scan. Six areas of the brain showed lower activation in the evening to both high- and low-energy foods, including structures in reward pathways (P brain regions showed significantly higher activation for high-energy foods compared to low-energy foods (P brain, regardless of time of day. However, evening scans showed a lower response to both low- and high-energy food pictures in some areas of the brain. Subjectively, participants reported no difference in hunger by time of day (F = 1.84, P = 0.19), but reported they could eat more (F = 4.83, P = 0.04) and were more preoccupied with thoughts of food (F = 5.51, P = 0.03) in the evening compared to the morning. These data underscore the role that time of day may have on neural responses to food stimuli. These results may also have clinical implications for fMRI measurement in order to prevent a time of day bias.

  11. Predictors of improvement in subjective sleep quality reported by older adults following group-based cognitive behavior therapy for sleep maintenance and early morning awakening insomnia.

    Science.gov (United States)

    Lovato, Nicole; Lack, Leon; Wright, Helen; Kennaway, David J

    2013-09-01

    Cognitive behavior therapy is an effective nonpharmacologic treatment for insomnia. However, individualized administration is costly and often results in substantial variability in treatment response across individual patients, particularly so for older adults. Group-based administration has demonstrated impressive potential for a brief and inexpensive answer to the effective treatment of insomnia in the older population. It is important to identify potential predictors of response to such a treatment format to guide clinicians when selecting the most suitable treatment for their patients. The aim of our study was to identify factors that predict subjective sleep quality of older adults following group-based administration of cognitive behavior therapy for insomnia (CBT-I). Eighty-six adults (41 men; mean age, 64.10 y; standard deviation [SD], 6.80) with sleep maintenance or early morning awakening insomnia were selected from a community-based sample to participate in a 4-week group-based treatment program of CBT-I. Participants were required to complete 7-day sleep diaries and a comprehensive battery of questionnaires related to sleep quality and daytime functioning. Hierarchical multiple regression analyses were used to identify factors predicting subjective sleep quality immediately following treatment and at 3-month follow-up. Sleep diaries reported average nightly sleep efficiency (SE), which was used as the outcome measure of sleep quality. Participants with the greatest SE following treatment while controlling for pretreatment SE were relatively younger and had more confidence in their ability to sleep at pretreatment. These characteristics may be useful to guide clinicians when considering the use of a group-based CBT-I for sleep maintenance or early morning awakening insomnia in older adults. Copyright © 2013 Elsevier B.V. All rights reserved.

  12. Salivary cortisol, alpha-amylase and immunoglobulin a responses to a morning session of basketball or volleyball training in boys aged 14-18 years.

    Science.gov (United States)

    Bruzda-Zwiech, A; Konieczka, M; Hilt, A; Daszkowska, M; Grzegorczyk, J; Szczepańska, J

    2017-01-01

    This study investigates whether a single session of routine morning basketball or volleyball training affects saliva levels of cortisol, alpha-amylase (sAA) and secretory immunoglobulin A (sIgA) in boys aged 14–18 years. Twenty-nine boys who participate in basketball or volleyball training, recruited from the Marcin Gortat’s Athletic Championship School in Lodz, were enrolled in the study. The 90-minute routine exercise program included 15 minutes of warm-up followed by basketball or volleyball practice. Unstimulated saliva samples were collected prior to and immediately after the exercise, and were analysed using ELISA. One training session resulted in a significant increase of sAA concentration in all participants, as well as in the volleyball and basketball subgroups (p=0.00022; p=0.0029; p=0.0011; respectively). Post-exercise cortisol levels were significantly lower than pre-exercise levels (p=0.00002) throughout the group, as well as in the volleyball and basketball subgroups (p=0.0048; p=0.0019; p=0.0048; respectively). The exercise protocol did not significantly affect sIgA level, either in the whole examined group or the volleyball subgroup, however a weak significant increase of sIgA was observed in the basketball subgroup (p=0.046). The routine morning training session comprising a warm-up followed by basketball or volleyball practice seems to activate the sympatho-adrenal-medullary system, with a subsequent increase of alpha-amylase, but does not affect oral immunity in 14-18-year-old boys.

  13. Flinging a New Star: “Fire and Cloud” and “Bright and Morning Star” as Reflections of Richard Wright’s Changing Relationship with Communism

    Directory of Open Access Journals (Sweden)

    April Conley Kilinski

    2012-10-01

    Full Text Available Richard Wright's collection of short novella's, Uncle Tom's Children, was originally published in 1938; in 1940, after the success of Native Son, a new printing of the text appeared with two additions. The first was the introductory essay entitled "The Ethics of Living Jim Crow," which was written in 1937, and later served as part of Black Boy. The second was the novella "Bright and Morning Star." Michel Fabre notes that Harper's Magazine rejected this story, "but since it fit Party specifications even better than had the four previous stories, New Masses published it as part of a special literary supplement on May 10, [1938]" (164 . In fact, perhaps because New Masses originally published the final story, critical attention to the revised edition of book almost exclusively posits that the 1940 edition reflects Wright's commitment to Communism at the time. However, several of Wright's other writings-including the introductory essay to the 1940 edition, "The Ethics of Living Jim Crow;" "Blue print for Negro Writing," first published in New Challenge in the fall of 1937; "I Tried to be a Communist," first published in Atlantic Monthly in August and September 1944; and his responses to the Communist party's review of Native Son in 1940-also indicate that his focus in the late 1930s was more on the development of an individual black consciousness than on advancing the causes of the Communist party. By juxtaposing the final two stories, "Fire and Cloud" and "Bright and Morning Star," and considering them in terms of the other writings indicated above, I argue that the 1940 edition of Uncle Tom's Children (with the two additions demonstrates Wright's growing ambivalence with the Communist Party between the years of 1937 and 1940.

  14. Effect of a single brushing with two Zn-containing toothpastes on VSC in morning breath: a 12 h, randomized, double-blind, cross-over clinical study.

    Science.gov (United States)

    Young, A; Jonski, G

    2011-12-01

    This randomized, double-blind, 12 h clinical study tested the effect of a single brushing with two Zn-containing toothpastes on volatile sulfur compound (VSC) levels in morning breath. The following toothpastes were each tested by all 28 participants: A-Zn toothpaste, B--experimental toothpaste (Zn citrate + PVM/MA copolymer) and C--control toothpaste without Zn. The evening prior to test days participants brushed their teeth for 2 min with 1 g toothpaste. 12 h later and prior to eating or performing oral hygiene, morning breath levels of VSC (H(2)S, CH(3)SH) were analysed by gas chromatography. Subjects then rinsed for 30 s with 5 ml cysteine and breath samples were analysed for H(2)S (H(2)S(cys)). Median VSC (area under the curve) values were compared for A, B and C and the effects of A and B on VSC were compared with C. Toothpaste B was more effective than both toothpastes A and C in reducing H(2)S, CH(3)SH and H(2)S(cys) (p toothpaste C, toothpastes A and B reduced H(2)S by 35% and 68%, respectively (p = 0.003), and CH(3)SH by 12% and 47%, respectively (p = 0.002). Toothpaste B reduced H(2)S(cys) by 48% compared with toothpaste C (p = 0.001). It is suggested that the superior effect of the experimental toothpaste was most likely due to a higher Zn concentration combined with longer retention of Zn due to the PVM/MA copolymer.

  15. Prolonged-release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects.

    Science.gov (United States)

    Lemoine, Patrick; Nir, Tali; Laudon, Moshe; Zisapel, Nava

    2007-12-01

    Melatonin, secreted nocturnally by the pineal gland, is an endogenous sleep regulator. Impaired melatonin production and complaints on poor quality of sleep are common among the elderly. Non-restorative sleep (perceived poor quality of sleep) and subsequently poor daytime functioning are increasingly recognized as a leading syndrome in the diagnostic and therapeutic process of insomnia complaints. The effects of 3-weeks prolonged-release melatonin 2 mg (PR-melatonin) versus placebo treatment were assessed in a multi-center randomized placebo-controlled study in 170 primary insomnia outpatients aged > or =55 years. Improvements in quality of sleep (QOS) the night before and morning alertness (BFW) were assessed using the Leeds Sleep Evaluation Questionnaire and changes in sleep quality (QON) reported on five categorical unit scales. Rebound insomnia and withdrawal effects following discontinuation were also evaluated. PR-melatonin significantly improved QOS (-22.5 versus -16.5 mm, P = 0.047), QON (0.89 versus 0.46 units; P = 0.003) and BFW (-15.7 versus -6.8 mm; P = 0.002) compared with placebo. The improvements in QOS and BFW were strongly correlated (Rval = 0.77, P insomnia or withdrawal effects following treatment discontinuation. The incidence of adverse events was low and most side-effects were judged to be of minor severity. PR-melatonin is the first drug shown to significantly improve quality of sleep and morning alertness in primary insomnia patients aged 55 years and older-suggesting more restorative sleep, and without withdrawal symptoms upon discontinuation.

  16. Analysis on the related factors of morning surge hypertension in patients with essential hypertension%原发性高血压患者晨间血压升高的相关因素分析

    Institute of Scientific and Technical Information of China (English)

    朱艳利; 王秀莉; 朱学梅; 卓晶明; 李文华

    2011-01-01

    目的 探讨原发性高血压(EH)患者晨间血压升高的相关因素.方法 对201例EH患者进行血压监测并记录晨峰(睡-谷晨峰值>10 mmHg)发生情况,比较发生晨峰者和未发生者一般资料及血脂、空腹血糖(FBG)、胰岛素(INS)、胰岛素抵抗指数(HOMA-IR)、纤维蛋白原(FIB)水平,对睡-谷晨峰值与上述指标的关系行Pearson相关分析.结果 59例血压出现晨峰现象(晨峰组),余142例未出现(非晨峰组);两组一般资料及血脂均无显著差异;晨峰组FBG、INS、FIB、HOMA-IR均显著高于非晨峰组(P均<0.05);晨峰组睡-谷晨峰值与FBG、INS、FIB、HOMA-IR均呈现正相关.结论 高血糖、胰岛素抵抗、高胰岛素血症及血液高凝状态等与EH患者晨间血压升高有关.%Objective To investigate the related factors of morning surge hypertension in patients with essential hypertension(EH). Methods The blood pressure of 201 patients with EH were monitored and the morning blood pressure surge ( sleep-trough morning surge variability > 10 mmHg )were recorded, patients with morning surge group or not were compared in the general information and the levels of blood fat, fasting blood glucose( FBG), insulin( INS), body mass index (BMI) insulin resistance index (HOMA-IR), fibrinogen. The correlation between sleep-trough morning surge variability and above indexes were analyzed. Results Fifty-nine patients showed morning blood pressure surge( MBPS group), and the other 142 patients were not found( NMBPS group); no difference were found between the two groups in the general information and blood fat; FBG, INS, FIB, HOMA-IR in the MBPS group were significantly higher than those in the NMBPS group ( all P < 0.05 ); sleep-trough morning surge variability was positively correlated with FBG, INS, FIB, HOMA-IR.Conclusions Morning surge hypertension is closely related with high blood glucose, insulin-resistance, hyperinsulinemia and blood high coagulation.

  17. Complications - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — Complications - national data. This data set includes national-level data the hip/knee complication measure, and the Agency for Healthcare Research and Quality...

  18. HCAHPS - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — The national average for the HCAHPS survey categories. HCAHPS is a national, standardized survey of hospital patients about their experiences during a recent...

  19. Payment - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — Payment measures – national data. This data set includes national-level data for the payment measures associated with an episode of care for heart attack, heart...

  20. Leptin Level and Skipping Breakfast: The National Health and Nutrition Examination Survey III (NHANES III)

    OpenAIRE

    Keiko Asao; Amandine Sambira Marekani; Jessica VanCleave; Amy E. Rothberg

    2016-01-01

    Skipping breakfast is a common dietary habit considered to be unhealthy. However, the mechanisms underlying skipping breakfast have not been fully explored. Leptin is a hormone that regulates food intake and energy storage and secretes in a diurnal rhythm with lowest levels in the morning. We examined the association between the serum leptin level and skipping breakfast in 5714 adults in the U.S. National Health and Nutrition Examination Survey III, 1988–1994. We defined breakfast as any food...

  1. 婴幼儿牵牛花综合征的临床特征分析%Analysis of clinical features in pediatric morning glory syndrome

    Institute of Scientific and Technical Information of China (English)

    许宇; 朱颖; 赵培泉; 李家恺; 董洋; 王诗园

    2012-01-01

    目的 分析总结婴幼儿牵牛花综合征患者的一般临床特征和眼底表现.方法 回顾性分析2006年6月至2010年6月于上海交通大学医学院附属新华医院眼科就诊的牵牛花综合征患儿的临床资料,统计分析患者性别、年龄、眼别及视力等情况.观察指标包括视力检查、眼内压检查、眼前节检查、眼底检查以及屈光度检查等.对病例进行计数并求百分比.结果 共有13例(14眼)被诊断为牵牛花综合征.患儿就诊时的年龄为2个月~6岁,平均(30.6±24.7)个月.其中男性7例(54%),女性6例(46%);6只(43%)为左眼,8只(57%)为右眼;除1例患者(8%)为双眼发病外,其余12例患者均为单眼发病.能够进行视力检查的8例患者的最佳矫正视力均低于0.1.所有患者眼底表现均非常典型,似盛开的牵牛花.其中有4例(4眼,28%)合并有永存原始玻璃体增生症,9例(9眼,64%)合并有黄斑异位,1例(2眼,14%)合并有视网膜脱离.结论 牵牛花综合征是一种严重影响患者视觉功能的先天缺陷综合征.准确及时的诊断和定期随访有利于保存这类患儿的视功能.%Objective To analyze and summarize the clinical features and ocular fundus of pediatric patients with morning glory syndrome.Methods In this retrospective study, the clinical data of pediatric patients with morning glory syndrome, who were treated from June 2006 to June 2010 at the Department of Ophthalmology, Xinhua Hospital, including sex, age, right or left eye and visual acuity,were analyzed.Main outcome measures were best corrected visual acuity (BCVA),intraocular pressure,ocular fundus and dioptroscopy.Results Thirteen patients (14 eyes),7 males (54%) and 6 females (46%),were diagnosed with morning glory syndrome.They were diagnosed at an average age of (30.6±24.7)months (range from 2 months to 6 years of age).The syndrome presented in 6 left eyes (43%) and 8 right eyes (57%).Only one patient presented

  2. Culinary nationalism.

    Science.gov (United States)

    Ferguson, Priscilla Parkhurst

    2010-01-01

    Culinary consciousness raisers, cooking texts often serve as vehicles of national identification. From Pampille (Marthe Allard Daudet) and her cookbook, Les Bons Plats de France, in 1913 to the international culinary competitions of today such as the Bocuse d'or, culinary distinction promotes national interests. In contrast to the strident nationalism of the early twentieth century, culinary nationalism today operates in an increasingly globalized world. National culinary distinction defines the nation and sells its products in a highly competitive international arena. A recent culinary text, the South Korean film Le Grand Chef [Sik Gaek ] (2007), illustrates the phenomenon, subsuming national culinary promotion in a mega culinary competition, all in the service of Korean culinary achievement.

  3. National Intelligence and National Prosperity

    Science.gov (United States)

    Hunt, Earl; Wittmann, Werner

    2008-01-01

    What is the relation between the cognitive competence of a national population that nation's economic prosperity? Lynn and Vanhanen [Lynn, R. & Vanhanen, T. (2002). "IQ and the wealth of nations." Westport, CT: Praeger.] presented data pointing to an exceptionally strong relationship between IQ scores and Gross Domestic Product per capita (GDP/c).…

  4. Comparison of evening and morning dosing of travoprost 0.004%/timolol 0.5% fixed combination in 6 month period.

    Science.gov (United States)

    Suić, Smiljka Popović; Laus, Katia Novak; Dosen, Vukosava Maricic; Ekert, Miroslav; Mandić, Zdravko; Bojić, Lovro

    2010-09-01

    An open label, multi-center, 6 months observational study of new fixed combination (travoprost 0.004%/timolol 0.5%), in order to evaluate both efficacy (intraocular pressure lowering) and tolerability (patient and investigator satisfaction) of two dosing regimens--evening (PM) and morning (AM). After screening for enrollment, to 40 patients (79 eyes with primary open angle glaucoma or ocular hypertension), new fixed combination travoprost 0.004%/timolol 0.5% was prescribed once a day in the evening (PM). Patients were enrolled according to each investigator decision on indication for travoprost 0.004%/timolol 0.5% fixed combination once a day, without washout period after previous medication. Intraocular pressure was measured at 9 AM at all time control points: at baseline, after 1 month, after 3 months and after 6 month. After 1 month, screening for nonresponders (criteria: 20% intraocular pressure lowering) and subjects with major side effects was performed. At second control visit, after 3 months PM dosing, intraocular pressure was measured and patients were instructed to continue once a day the same medication, but in the morning (AM) for consequent 3 months. After 1 month, reduction in mean intraocular pressure value was 21.66%. At the visit after 3 month, the mean intraocular pressure was 15.67 +/- 2.17 mm Hg (reduction 21.14%). 3 month after dosing regimen changed to AM (6 month after beginning of travoprost 0.004%/timolol 0.5% combination therapy), reduction in intraocular pressure value was 19.86%. The differences (mean +/- standard deviation) in intraocular pressure values after 1, 3 and 6 month were all highly statistically significant compared to baseline values. The tolerability was evaluated in five steps (Likert scale) ranging from unsatisfactory to excellent by both patient and investigator--taken at 3 and 6 month control visit. 95% of patients and 100% of investigators were satisfied with the possibility of choosing dosing regimen for travoprost 0

  5. Geography and niche occupancy as determinants of yeast biodiversity: the yeast-insect-morning glory ecosystem of Kīpuka Puaulu, Hawai'i.

    Science.gov (United States)

    Lachance, Marc André; Bowles, Jane M; Starmer, William T

    2003-10-01

    Biodiversity theory proposes two types of hypotheses to account for the species composition of a given community. The first encompasses geographic and historical factors. For example, local species richness is thought to be affected by area, proximity to large landmasses, dispersal mechanisms, and climatic history, collectively known as biogeography. The second type, termed niche occupancy rules, deals with the intrinsic properties of the species as they affect their interaction with the habitat and with other members of the community. The yeast-insect-morning glory ecosystem is a good model to explore biodiversity theory in ascomycetous yeasts. Here we focus on beetles that breed or feed in morning glories and a group of ascomycetous yeasts that are associated exclusively with them. Specifically, we analyse the community found in the vicinity of Kīpuka Puaulu, a small patch of disturbed but mature forest situated amidst lava flows on the island of Hawai'i. Major members of the yeast community include Metschnikowia hawaiiensis, Metschnikowia lochheadii, and the related asexual species Candida ipomoeae and Candida kipukae. These species are nearly indistinguishable from one another in terms of nutritional requirements and abilities, although their phylogenetic range is enormous. Their distribution, both global and local, is far from random. As Kīpuka Puaulu is an island within an island, the principles of island biogeography may be invoked to explain some aspects of its yeast species composition. M. lochheadii, C. ipomoeae, and the rare species Candida hawaiiana are recent introductions from the American continent and therefore exotic, whereas M. hawaiiensis and C. kipukae might be regarded as endemic, as they are yet to be isolated elsewhere. Vectoring by certain nitidulid beetles explains the long-range dispersal of these species. However, niche occupancy rules may account in part for the local spatial distribution of the yeasts within the island of Hawai'i and

  6. Negative association between plasma aldosterone concentration/plasma renin activity and morning blood pressure surge in never-treated hypertensive patients.

    Science.gov (United States)

    Cho, Jung Sun; Ihm, Sang Hyun; Jang, Sung-Won; Chung, Woo-Baek; Choi, Yun-Seok; Shin, Dong-Il; Seo, Suk Min; Park, Mahn-Won; Kim, Gee Hee; Her, Sung-ho; Kim, Chan Joon; Kim, Tae-Hoon; Kang, Min Kyu; Chang, Kiyuk; Park, Chan Seok

    2014-01-01

    Morning blood pressure (BP) surge (MS) has been known to be a predictor of cardiovascular events. Currently, few studies have evaluated the underlying mechanism underlying MS, which may include neurohormonal factors and the renin-angiotensin-aldosterone system (RAAS). This study aimed to examine plasma aldosterone concentration (PAC) and plasma renin activity (PRA) and BP parameters with or without MS in never-treated subjects with essential hypertension. This cross-sectional study included a total of 261 patients (mean age: 48.8 years; 60.5% male) with never-treated essential hypertension who were registered in a working group at The Catholic University of Korea. The patients were divided into the MS group, which was defined as having the highest quartile of morning BP increase from sleep (>31 mmHg; n = 66) and the non-MS group (≤31 mmHg; n = 195). We collected 24-h ambulatory BP, pulse wave velocity, ankle brachial index, PAC and PRA from all patients. The measured PAC and PRA were lower in the MS group than in the non-MS group (PAC: 9.0 ± 5.4 ng/dl versus 12.2 ± 8.7 ng/dl, p < 0.001; PRA: 1.7 ± 1.3 ng/ml/h versus 2.6 ± 3.6 ng/ml/h, p = 0.002). The MS group had greater variations in daytime, nighttime and 24-h systolic blood pressure (SBPs) than the non-MS group (24-h SBP: 15.6 ± 4.4 mm Hg for the non-MS group and 18.9 ± 4.9 mmHg for the MS group; p < 0.001 for each). It is generally accepted that the sympathetic nervous system plays a major role in the regulation of BP variability. Therefore, further studies on sympathetic nervous system activation in hypertensives with extreme MS are needed. MS in enrolled patients who were at relatively low risk in this study may be less affected by the RAAS.

  7. Using bedtime (PM) and early morning (AM) urine cortisol/creatinine ratios to evaluate pituitary-adrenal function in an office practice.

    Science.gov (United States)

    Burch, Warner

    2011-01-01

    To evaluate the use of cortisol/creatinine ratios in urine specimens collected at bedtime (PM) and the following morning (AM) in a general endocrine practice as a means of assessing pituitary-adrenal function in normal volunteers, outpatients with symptoms but no clinical endocrine dysfunction, patients with Cushing syndrome, and patients with known hypopituitarism. Double-voided PM and AM urine samples were collected from 26 healthy control subjects and 131 outpatients who had complaints of fatigue and malaise, inability to lose weight, or nonspecific concerns about potential underlying problems with their metabolism. The findings on physical examination and laboratory studies were normal in each of these outpatients. Urine was assayed for free cortisol and creatinine and expressed as ng of cortisol/mg of creatinine. Eleven patients with documented Cushing syndrome also collected urine specimens, and data for 11 patients with known hypopituitarism were also studied. A clear diurnal pattern of low cortisol excretion at night that increased some 7-fold in the morning (PAM cortisol/creatinine was 91.5 (95% CI, 65.0 to 118.0). The mean AM/PM ratio was 6.9, and the mean difference in AM-PM was 75.7. In the outpatients, there was no significant difference in PM, AM, AM/PM, and AM-PM values in comparison with those in healthy control subjects, and no significant difference was noted in these variables among the 3 groups of outpatients (those with fatigue, weight gain, and metabolism concerns). In 11 patients with Cushing syndrome, the mean PM urine cortisol/creatinine ratio was 127.0 (95% CI, 87.0 to 166.0), and there was loss of diurnal variation with the AM/PM ratio of 1.16 (95% CI, 0.98 to 1.35). Patients with hypopituitarism had little to no increase in AM urine cortisol/creatinine in comparison with PM urine cortisol/creatinine. Determination of PM and AM urine cortisol/creatinine ratios offers a convenient method for assessing pituitary-adrenal function.

  8. Is a split-dose regimen of 2 L polyethylene glycol plus ascorbic acid tolerable for colonoscopy in an early morning visit to a comprehensive medical check-up?

    Science.gov (United States)

    Seo, Ji Yeon; Lee, Changhyun; Jin, Eun Hyo; Yun, Mi Hyun; Lim, Joo Hyun; Kang, Hae Yeon; Yang, Jong In; Chung, Su Jin; Yang, Sun Young; Kim, Joo Sung

    2017-01-01

    AIM To evaluate the effectiveness and tolerability of a split-dose 2 L polyethylene glycol (PEG)/ascorbic acid (AA) regimen for healthy examinees who visited for comprehensive medical check-up in the early morning. METHODS From February 2015 to March 2015, examinees of average risk who were scheduled for a colonoscopy in the morning were retrospectively enrolled. RESULTS The 189 examinees were divided into split-dose and non-split-dose groups. The adequacy of bowel preparation for the split-dose group vs the non-split-dose group was 96.8% vs 85.2%, respectively, P sleep disturbance (P < 0.001) was more prevalent in the split-dose group, however the willingness to repeat the same preparation method (P = 0.243) was not different in both groups. The split-dose regimen was the most important factor influencing adequate bowel preparation in multivariate analysis (HR = 10.89, 95%CI: 6.53-18.17, P < 0.001). CONCLUSION A split-dose regimen of 2 L PEG/AA for an early morning colonoscopy was more effective and showed better compliance for diet restriction without any difference in satisfaction and discomfort. Introducing a split-dose regimen of 2 L PEG/AA to morning colonoscopy examinees is effective and tolerable in a comprehensive medical check-up setting.

  9. National Parks

    Data.gov (United States)

    Department of Transportation — National Park Service unit boundaries (NTAD). These park boundaries signify legislative boundary definitions and local park names have been consolidated according to...

  10. "It's tough hanging-up a call": The relationships between calling and work hours, psychological detachment, sleep quality, and morning vigor.

    Science.gov (United States)

    Clinton, Michael E; Conway, Neil; Sturges, Jane

    2017-01-01

    It has been argued that when people believe that their work is a calling, it can often be experienced as an intense and consuming passion with significant personal meaning. While callings have been demonstrated to have several positive outcomes for individuals, less is known about the potential downsides for those who experience work in this way. This study develops a multiple-meditation model proposing that, while the intensity of a calling has a positive direct effect on work-related vigor, it motivates people to work longer hours, which both directly and indirectly via longer work hours, limits their psychological detachment from work in the evenings. In turn, this process reduces sleep quality and morning vigor. Survey and diary data of 193 church ministers supported all hypotheses associated with this model. This implies that intense callings may limit the process of recovery from work experiences. The findings contribute to a more balanced theoretical understanding of callings. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  11. Consuming polydextrose in a mid-morning snack increases acute satiety measurements and reduces subsequent energy intake at lunch in healthy human subjects.

    Science.gov (United States)

    Hull, Sarah; Re, Roberta; Tiihonen, Kirsti; Viscione, Luisa; Wickham, Martin

    2012-12-01

    Polydextrose (Litesse®, DuPont) is a polysaccharide that is partially fermented in the colon. Evidence suggests that polydextrose increases satiety when consumed over several weeks; however studies assessing its acute effects on satiety are lacking. This study therefore aimed to assess the impact of different doses of polydextrose on satiety and energy intake at subsequent meals during a test day. Three yogurt-based drinks containing different amounts of polydextrose (0, 6.25 and 12.5g) were tested using a randomised, single-blinded, placebo controlled, cross-over design. Thirty-four healthy male and female volunteers were provided with a standard breakfast, then consumed the test product mid-morning, 90min before an ad libitum lunch, which was followed by an ad libitum dinner. Visual analogue scales were used to measure subjective ratings of appetite, liking and discomfort. Consuming 6.25 and 12.5g polydextrose increased satiety and decreased appetite compared to control immediately after consumption. A reduction in energy intake (218.8kJ) at lunchtime was observed for 12.5g polydextrose. This reduction in energy intake was not compensated for at dinner. This study suggests that polydextrose may aid in increasing satiety feelings post consumption and also reduce energy intake as a result.

  12. Monday Morning Among the Muslims

    Institute of Scientific and Technical Information of China (English)

    ADAM; MOORMAN

    2011-01-01

    Heat,history and culture of the Hui ethnic group—those are the three things first coming to mind when I think of Xi’an,capital city of northwest China’s Shaanxi Province.The Hui people are Xi’an’s native Muslim population

  13. Easy Like a Sunday Morning

    DEFF Research Database (Denmark)

    Erz, Antonia; Christensen, Bo T.; Tomczak, Torsten

    This research investigates how consumers judge innovations based on the meta-cognitive experiences they draw from the processing fluency of analogies in ads. An online experiment with 503 consumers tests the relationship between analogy similarity and processing fluency, and the effect the fluenc...... of analogies has on innovation liking and purchase intention....

  14. 利用晨交班提高手术室护士人文素质的相关研究%Exploring Effective Way for Improving Operating Room Nurses′Humanistic Exploring Effective Way for Improving Operating Room Nurses′Humanistic Quality by Using the Morning Shift Time Quality by Using the Morning Shift Time

    Institute of Scientific and Technical Information of China (English)

    孔德玲; 王明旭; 孔德敏; 李向利; 孔淑贞; 赵丽燕; 权小利

    2015-01-01

    Objective:To explore the effective way of cultivating the operating room nurses′humanistic quality by using the morning shift and to improve operating room nurses′comprehensive quality .Methods:The operating room nurses were divided into five specialist groups according to the nurses′levels, helping each group to determine the training topic of humanistic quality training , via taking a variety of training methods to promote operating room nurses′humanistic quality by making good use of the morning shift time .Results: Through taking a variety of training methods to promote the operating room nurses′humanistic quality by making good use of the morning shift time, the operating room nurses′humanistic care ability , theoretical knowledge , professional skills were improved significantly(P<0.05),and the operating rooms doctors, surgical patients′satisfaction of operating room nurses′service were improved ( P<0 .05 ) .Conclusion:Making good use of the morning shift time to improve the nurses′humanistic quality , at the same time , the nursing service quality and patients satisfaction were also improved .%目的:通过有效利用晨交班,采取一系列提高手术室护士人文素质的相关措施,以提高手术室护士的综合素质。方法将手术室护士按不同层级搭配,分成五个专科小组,指导各组护士结合本科室手术室护士的实际工作情况选定相关的人文素质培训主题,充分利用晨交班时间,通过多种培训手段对全科护士进行培训。结果有效利用晨交班时间,采取一系列措施提高手术室护士人文素质后,手术室护士的人文关怀能力、理论知识以及专业技能考核成绩较实施前有显著提高,差异有统计学意义(P<0.05);与此同时手术医师以及患者对手术室护理的满意度也有了较大的提升(P<0.05)。结论有效利用晨交班时间,通过采取有效措施促进手术室护士人

  15. Responsible nations

    DEFF Research Database (Denmark)

    Lippert-Rasmussen, Kasper

    2009-01-01

    In National Responsibility and Global Justice, David Miller defends the view that a member of a nation can be collectively responsible for an outcome despite the fact that: (i) she did not control it; (ii) she actively opposed those of her nation's policies that produced the outcome; and (iii......) actively opposing the relevant policy was costly for her. I argue that Miller's arguments in favor of this strong externalist view about responsibility and control are insufficient. Specifically, I show that Miller's two models of synchronic collective responsibility*the like-minded group model...

  16. Trauma morning report is the ideal environment to teach and evaluate resident communication and sign-outs in the 80 hour work week.

    Science.gov (United States)

    Ottinger, Mary E; Monaghan, Sean F; Gregg, Shea C; Stephen, Andrew H; Connolly, Michael D; Harrington, David T; Adams, Charles A; Cioffi, William G; Heffernan, Daithi S

    2017-09-01

    The 80h work week has raised concerns that complications may increase due to multiple sign-outs or poor communication. Trauma Surgery manages complex trauma and acute care surgical patients with rapidly changing physiology, clinical demands and a large volume of data that must be communicated to render safe, effective patient care. Trauma Morning Report format may offer the ideal situation to study and teach sign-outs and resident communication. Surgery Residents were assessed on a 1-5 scale for their ability to communicate to their fellow residents. This consisted of 10 critical points of the presentation, treatment and workup from the previous night's trauma admissions. Scores were grouped into three areas. Each area was scored out of 15. Area 1 consisted of Initial patient presentation. Area 2 consisted of events in the trauma bay. Area 3 assessed clarity of language and ability to communicate to their fellow residents. The residents were assessed for inclusion of pertinent positive and negative findings, as well as overall clarity of communication. In phase 1, residents were unaware of the evaluation process. Phase 2 followed a series of resident education session about effective communication, sign-out techniques and delineation of evaluation criteria. Phase 3 was a resident-blinded phase which evaluated the sustainability of the improvements in resident communication. 50 patient presentations in phase 1, 200 in phase 2, and 50 presentations in phase 3 were evaluated. Comparisons were made between the Phase 1 and Phase 2 evaluations. Area 1 (initial events) improved from 6.18 to 12.4 out of 15 (pcommunication and language) improved from 8.36 to 12.22 out of 15 (Pcommunication skills in residents. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Combined optical, EISCAT and magnetic observations of the omega bands/Ps6 pulsations and an auroral torch in the late morning hours: a case study

    Directory of Open Access Journals (Sweden)

    V. Safargaleev

    2005-07-01

    Full Text Available We present here the results of multi-instrument observations of auroral torch and Ps6 magnetic pulsations, which are assumed to be the magnetic signature of the spatially periodic optical auroras known as omega bands. Data from TV and ASC cameras in Barentsburg and Ny Ålesund, EISCAT radars in Longyearbyen and Tromsø, as well as IMAGE network were used in this study. The auroral phenomenon which was considered differed from that previously discussed, as it occurred both in an unusual place (high latitudes and at an unusual time (late morning hours. We show that this might occur due to specific conditions in the interplanetary medium, causing the appropriate deformation of the magnetosphere. In such a case, the IMF turned out to be an additional factor in driving the regime of Ps6/omega bands, namely, only by acting together could a substorm onset in the night sector and Bz variations result in their generation. Since the presumable source of Ps6/omega bands does not co-locate with convection reversal boundaries, we suggest the interpretation of the phenomena in the frame of the interchange instability instead of the Kelvin-Helmholtz instability that is widely discussed in the literature in connection with omega auroras. Some numerical characteristics of the auroral torch were obtained. We also emphasize to the dark hole in the background luminosity and the short-lived azimuthally-restricted auroral arc, since their appearance could initiate the auroral torch development.

    Keywords. Magnetospheric physics (Auroral phenomena; Plasma convection; Solar wind-magnetosphere interaction

  18. Sleep length as a function of morning shift-start time in irregular shift schedules for train drivers: self-rated health and individual differences.

    Science.gov (United States)

    Ingre, Michael; Kecklund, Göran; Akerstedt, Torbjörn; Söderström, Marie; Kecklund, Lena

    2008-04-01

    Forty-six male train drivers (mean age = 46.5, SD = 5.1) were recruited to participate in a diary study for 14 consecutive days with questions about their sleep and working hours. A polynomial mixed-effect regression model showed a curvilinear relation ( p sleep duration for shifts starting at 03:00-12:00 hand with a near linear increase for ones starting between 04:30 and 09:00 h of approximately 0.7 h for every 1 h the shift was delayed. The longest sleeps were estimated at approximately 8 h before shifts that started at approximately 10:00 h. The shortest sleeps were found for shifts that started before 04:30 h and were estimated at approximately 5 h. Individual differences were estimated with a random-effect standard deviation of 0.51 h, independent of shift start time ( p = .005). One-half of the between-subject variance was explained by subjective health. A one-step decrease in health was associated with a 26 min increase in sleep length. The results have practical implications for constructing shift schedules. Early morning shifts reduced sleep length substantially and should be mixed with later start hours to avoid the accumulation of sleep dept. Delaying the shift-start past 10:00 h had little effect on sleep opportunity; however, delaying shift-start to between 04:30 and 9:00 h had a strong impact on sleep length, with 70% of the extra time used for sleep, suggesting large positive effects for this range of shift-start times.

  19. Xanthophyll Cycle and Inactivation of Photosystem Ⅱ Reaction Centers Alleviating Reducing Pressure to Photosystem Ⅰ in Morning Glory Leaves under Short-term High Irradiance

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    investigated through chlorophyll fluorescence parameters in morning glory (Ipomoea setosa) leaves, which were dipped into water, dithiothreitol (DTT) and lincomycin (LM), respectively. During the stress, both the xanthophyll cycle and D1 protein turnover could protect PSI from photoinhibition. In DTT leaves, non-photochemical quenching (NPQ) was inhibited greatly and the oxidation level of P700 (P700+) was the lowest one. However, the maximal photochemical efficiency of PSII (Fv/Fm) in DTT leaves was higher than that of LM leaves and was lower than that of control leaves. These results suggested that PSI was more sensitive to the loss of the xanthophyll cycle than PSII under high irradiance. In LM leaves, NPQ was partly inhibited, Fv/Fm was the lowest one among three treatments under high irradiance and P700+ was at a similar level as that of control leaves. These results implied that inactivation of PSII reaction centers could protect PSI from further photoinhibition. Additionally, the lowest of the number of active reaction centers to one inactive reaction center for a PSII cross-section (RC/CSo), maximal trapping rate in a PSII cross-section (TRo/CSo), electron transport in a PSII cross-section (ETo/CSo) and the highest of 1-qP in LM leaves further indicated that severe photoinhibition of PSII in LM leaves was mainly induced by inactivation of PSII reaction centers, which limited electrons transporting to PSI. However, relative to the LM leaves the higher level of RC/CSo, TRo/CSo, Fv/Fm and the lower level of 1-qP in DTT leaves indicated that PSI photoinhibition was mainly induced by the electron accumulation at the PSI acceptor side, which induced the decrease of P700+ under high irradiance.

  20. Early morning urine collection to improve urinary lateral flow LAM assay sensitivity in hospitalised patients with HIV-TB co-infection.

    Science.gov (United States)

    Gina, Phindile; Randall, Philippa J; Muchinga, Tapuwa E; Pooran, Anil; Meldau, Richard; Peter, Jonny G; Dheda, Keertan

    2017-05-12

    Urine LAM testing has been approved by the WHO for use in hospitalised patients with advanced immunosuppression. However, sensitivity remains suboptimal. We therefore examined the incremental diagnostic sensitivity of early morning urine (EMU) versus random urine sampling using the Determine® lateral flow lipoarabinomannan assay (LF-LAM) in HIV-TB co-infected patients. Consenting HIV-infected inpatients, screened as part of a larger prospective randomized controlled trial, that were treated for TB, and could donate matched random and EMU samples were included. Thus paired sample were collected from the same patient, LF-LAM was graded using the pre-January 2014, with grade 1 and 2 manufacturer-designated cut-points (the latter designated grade 1 after January 2014). Single sputum Xpert-MTB/RIF and/or TB culture positivity served as the reference standard (definite TB). Those treated for TB but not meeting this standard were designated probable TB. 123 HIV-infected patients commenced anti-TB treatment and provided matched random and EMU samples. 33% (41/123) and 67% (82/123) had definite and probable TB, respectively. Amongst those with definite TB LF-LAM sensitivity (95%CI), using the grade 2 cut-point, increased from 12% (5-24; 5/43) to 39% (26-54; 16/41) with random versus EMU, respectively (p = 0.005). Similarly, amongst probable TB, LF-LAM sensitivity increased from 10% (5-17; 8/83) to 24% (16-34; 20/82) (p = 0.001). LF-LAM specificity was not determined. This proof of concept study indicates that EMU could improve the sensitivity of LF-LAM in hospitalised TB-HIV co-infected patients. These data have implications for clinical practice.

  1. A petal-specific InMYB1 promoter from Japanese morning glory: a useful tool for molecular breeding of floricultural crops.

    Science.gov (United States)

    Azuma, Mirai; Morimoto, Reina; Hirose, Mana; Morita, Yasumasa; Hoshino, Atsushi; Iida, Shigeru; Oshima, Yoshimi; Mitsuda, Nobutaka; Ohme-Takagi, Masaru; Shiratake, Katsuhiro

    2016-01-01

    Production of novel transgenic floricultural crops with altered petal properties requires transgenes that confer a useful trait and petal-specific promoters. Several promoters have been shown to control transgenes in petals. However, all suffer from inherent drawbacks such as low petal specificity and restricted activity during the flowering stage. In addition, the promoters were not examined for their ability to confer petal-specific expression in a wide range of plant species. Here, we report the promoter of InMYB1 from Japanese morning glory as a novel petal-specific promoter for molecular breeding of floricultural crops. First, we produced stable InMYB1_1kb::GUS transgenic Arabidopsis and Eustoma plants and characterized spatial and temporal expression patterns under the control of the InMYB1 promoter by histochemical β-glucuronidase (GUS) staining. GUS staining patterns were observed only in petals. This result showed that the InMYB1 promoter functions as a petal-specific promoter. Second, we transiently introduced the InMYB1_1 kb::GUS construct into Eustoma, chrysanthemum, carnation, Japanese gentian, stock, rose, dendrobium and lily petals by particle bombardment. GUS staining spots were observed in Eustoma, chrysanthemum, carnation, Japanese gentian and stock. These results showed that the InMYB1 promoter functions in most dicots. Third, to show the InMYB1 promoter utility in molecular breeding, a MIXTA-like gene function was suppressed or enhanced under the control of InMYB1 promoter in Arabidopsis. The transgenic plant showed a conspicuous morphological change only in the form of wrinkled petals. Based on these results, the InMYB1 promoter can be used as a petal-specific promoter in molecular breeding of floricultural crops.

  2. Lucky morning glory, Calystegia felix (Convolvulaceae: a new species from Southern California, with notes on the historical ecology of the Chino ciénega belt

    Directory of Open Access Journals (Sweden)

    Mitchell Provance

    2013-12-01

    Full Text Available A new morning glory, Calystegia felix Provance & A.C. Sanders sp. nov. (Convolvulaceae, is described from the Los Angeles, San Gabriel, and Santa Ana River basins. Historical collections of the species, which prior to 2011 had not been seen alive in 94 years, have been misidentified as Calystegia sepium (L. R. Br. subsp. binghamiae (Greene Brummitt. The undescribed species was rediscovered in the City of Chino in April of 2011, a few miles north of the location where the most recent previous collection had been made by I. M. Johnston in 1917. The plants were found just prior to their likely destruction by grading and trenching for an underground power line. Intensive searches have resulted in the discovery of five additional occurrences, all of them in the City of Chino. Calystegia felix is at high risk of soon becoming extinct in the wild. All of the known extant occurrences are associated with well-watered landscaping on recently completed industrial, commercial, and residential developments. Every known living occurrence is within the limits of a ciénega belt, which is now mostly historical. Otherwise, the new species is only known only from collections made around the turn of the 20th century in what are now heavily urbanized areas, including one from South Los Angeles and another from Pico Rivera in Los Angeles County. Calystegia felix lacks the large bracts that immediately subtend, and enclose the calyx, which are always present in members of the C. sepium complex. Affinities to C. felix are found among other western US species with graduated sepals and small, often somewhat remote bracts. We discuss the enduring confusion between C. felix and C. sepium subsp. binghamiae, and differentiate the new species from some of its more likely relatives. The taxonomic treatment is supplemented by photos of herbarium specimens and living plants. We also discuss the ecological setting of Chino’s ciénega belt, which was a mosaic of palustrine

  3. National database

    DEFF Research Database (Denmark)

    Kristensen, Helen Grundtvig; Stjernø, Henrik

    1995-01-01

    Artikel om national database for sygeplejeforskning oprettet på Dansk Institut for Sundheds- og Sygeplejeforskning. Det er målet med databasen at samle viden om forsknings- og udviklingsaktiviteter inden for sygeplejen.......Artikel om national database for sygeplejeforskning oprettet på Dansk Institut for Sundheds- og Sygeplejeforskning. Det er målet med databasen at samle viden om forsknings- og udviklingsaktiviteter inden for sygeplejen....

  4. Nation First

    Institute of Scientific and Technical Information of China (English)

    He Tao

    2012-01-01

    In addition to the success of onomic integration,the ultural effects of globalization have been considerable.The increasingly globalized culture creates the potential to alter the way people identify themselves,eroding geographic boundaries as well as local and national cultures.While the West was happily appreciating this gift from globalization,they found themselves involved in an unexpected wave of reemerging nationalism in many countries.

  5. Étude des propriétés mécaniques et rhéologiques d'échantillons de marne de la formation géologique "Morne Delmas" en Haïti

    OpenAIRE

    Guerrier, Kelly

    2013-01-01

    Haiti, like many other countries, is facing several problems in relation to its subsoil. Frequent cases of ground movement are observed in Port-au-Prince and its metropolitan area. These problems are caused by the swelling properties of the clays contained in the marl of the Morne Delmas geological formation. In addition, the pollution of these soils by waste water modify their mechanical properties, which is much more worrying considering that the country is located in one of the region of t...

  6. A randomized, double-masked, placebo-controlled crossover trial on the effects of L-ornithine on salivary cortisol and feelings of fatigue of flushers the morning after alcohol consumption

    Directory of Open Access Journals (Sweden)

    Kokubo Takeshi

    2013-02-01

    Full Text Available Abstract Background Residual alcohol effects on physiological and psychological symptoms are commonly experienced the morning after alcohol consumption. The purpose of this study was to assess the effects of L-ornithine on subjective feelings and salivary stress markers the morning after alcohol consumption and to investigate whether L-ornithine acutely accelerates ethanol metabolism. Methods This study had a randomized, placebo-controlled, double-masked crossover design. Subjects were all healthy Japanese adults with the ‘flusher’ phenotype for alcohol tolerance. In experiment 1, 11 subjects drank 0.4 g/kg body weight alcohol 1.5 h before their usual bedtime. Half an hour after drinking, they ingested either a placebo or 400 mg ornithine. The next morning on awakening, subjects completed a questionnaire containing a visual analog scale (VAS, the Oguri-Shirakawa-Azumi sleep inventory MA version (OSA-MA, and a profile of mood states (POMS and collected a saliva sample for measurement of salivary stress markers (cortisol, secretory immunoglobulin A, and α-amylase. In experiment 2, placebo or 400 mg ornithine were administrated to 16 subjects both before and after drinking, and the feeling of drunkenness, breath ethanol concentration and one-leg standing time were repeatedly investigated until 180 min after alcohol consumption. Results There were significant decreases in “awareness”, “feeling of fatigue” and “lassitude” VAS scores and in “anger-hostility” and “confusion” POMS scores and a significant increase in “sleep length” in the OSA-MA test. Salivary cortisol concentrations on awakening were reduced after ornithine supplementation. There were no differences between ornithine and placebo in any of the subjective or physiological parameters of acute alcohol metabolism. Conclusions Taking 400 mg ornithine after alcohol consumption improved various negative feelings and decreased the salivary stress marker cortisol the

  7. The Bottom Class Children Happy Morning Sports Activities Carried out Effectively%小班幼儿快乐晨间体育活动的有效开展

    Institute of Scientific and Technical Information of China (English)

    程国琴

    2014-01-01

    “Kindergarten education guidelines”put forward the infant health perspectives of “paying equal attention to body and mind”, and put the children on the first of five fields. Morning effective to organize the implementation of outdoor sports,which is an effective way to promote children’s physical and mental development, one hour in the morning is worth two in the evening, every reasonable scientific effectively organized outdoor morning sports activities can make children have a strong and healthy physique, more sunshine, cheerful, lively personality.%《幼儿园教育指导纲要》提出“身心并重”的幼儿健康观,并将幼儿健康放在了五大领域的首位。晨间户外体育活动的有效组织实施,是促进幼儿身心发展的有效途径,一日之计在于晨,每天合理科学有效地组织晨间户外体育活动,可以使幼儿拥有健康强壮的体质,更阳光、开朗、活泼的个性。

  8. 牡丹江市老年人晨练点锻炼行为的社会学分析%Sociological Analysis on the Exercise Behavior of the El-derly at Morning Exercise Sites in Mudanjiang City

    Institute of Scientific and Technical Information of China (English)

    苏贵斌; 张彦龙; 马志君

    2014-01-01

    研究通过文献资料法、问卷调查法等方法,运用了社会学的研究视角,对牡丹江市晨练点老年人参与体育活动进行了相关的分析。分析得出,牡丹江市晨练点兴起的社会条件有三个:一是经济的发展是其兴起的基础条件;二是休闲时间的增多提供了时间保证;三是人们的主观意识是其内在动力。%Through literature, questionnaire survey and other methods, using the sociological research perspective, this paper made relevant analysis on senior citizens' participation in sports activities at morning exercise sites in Mudanjiang City. We hold that there are three social conditions leading to the rise of morn-ing exercise sites in Mudanjiang City: first, economic develop-ment is the basic condition of its rise; second, an increase in leisure time has provided enough time;third, people's subjective consciousness is the inner motivation.

  9. Is there a link between hyperuricemia, morning blood pressure surge, and non-dipping blood pressure pattern in metabolic syndrome patients?

    Directory of Open Access Journals (Sweden)

    Tutal E

    2013-04-01

    Full Text Available Emre Tutal,1 Burak Sayin,1 Derun Taner Ertugrul,2 Avsin Ibis,1 Siren Sezer,1 Nurhan Özdemir1 1Department of Nephrology, Baskent University Hospital, 2Department of Endocrinology and Metabolism, Keçiören Training and Research Hospital, Ankara, Turkey Background: Hypertensive patients usually have a blunted nocturnal decrease, or even increase, in blood pressure during sleep. There is also a tendency for increased occurrence of cardiovascular events between 6 and 12 am due to increased morning blood pressure surge (MBPS. Co-occurrence of metabolic syndrome (MetS and hypertension is also a common problem. Hyperuricemia might trigger the development of hypertension, chronic renal failure, and insulin resistance. In this study, we aimed to determine whether there is a relationship between hyperuricemia, MetS, nocturnal blood pressure changes, and MBPS. Method: A total of 81 newly diagnosed hypertensive MetS patients were included in this study. Ambulatory blood pressure monitoring of patients was done and patients’ height, weight, and waist and hip circumferences were recorded. Fasting blood glucose (FBG, lipid profile, creatinine, potassium, uric acid, hematocrit levels were studied. Results: Non-dipper (ie, those whose blood pressure did not drop overnight patients had higher waist–hip ratios (WHR (P = 0.003, uric acid (P = 0.0001, FBG (P = 0.001, total and low-density lipoprotein cholesterol levels (P = 0.0001. Risk analysis revealed that hyperuricemia was a risk factor for non-dipping pattern (P < 0.0001, odds ratio = 8.1, 95% confidence interval = 1.9–33.7. Patients in the highest quadrant for uric acid levels had higher FBG (P = 0.001, low-density lipoprotein cholesterol (P = 0.017, WHR (P = 0.01, MBPS (P = 0.003, and night diastolic blood pressure compared with lowest quadrant patients (P = 0.013. Uric acid levels were also positively correlated with night ambulatory blood pressure (ABP (r = 0.268, P = 0.05, night diastolic blood

  10. Myopic defocus in the evening is more effective at inhibiting eye growth than defocus in the morning: Effects on rhythms in axial length and choroid thickness in chicks.

    Science.gov (United States)

    Nickla, Debora L; Thai, Pearl; Zanzerkia Trahan, Rinita; Totonelly, Kristen

    2017-01-01

    Animal models have shown that myopic defocus is a potent inhibitor of ocular growth: brief (1-2 h) daily periods of defocus are sufficient to counter the effects of much longer periods of hyperopic defocus, or emmetropic vision. While the variables of duration and frequency have been well-documented with regard to effect, we ask whether the efficacy of the exposures might also depend on the time of day that they are given. We also ask whether there are differential effects on the rhythms in axial length or choroidal thickness. 2-week-old chickens were divided into 2 groups: (1) "2-hr lens-wear". Chicks wore monocular +10D lenses for 2 h per day for 5 days at one of 3 times of day: 5:30 a.m. (n = 11), 12 p.m. (n = 8) or 7:30 p.m. (n = 11). (2) "2-hr minus lens-removal". Chicks wore monocular -10D lenses continually for 7 days, except for a 2-hr period when lenses were removed; the removal occurred at one of 2 times: 5:30 a.m. (n = 8) or 7:30 p.m. (n = 8). Both paradigms exposed eyes to brief myopic defocus that differed in its magnitude, and in the visual experience for the rest of the day. High frequency A-scan ultrasonography was done at the start of the experiment; on the last day, it was done at 6-hr intervals, starting at noon, over 24-hr, to assess rhythm parameters. Refractive errors were measured using a Hartinger's refractometer at the end. In both paradigms, myopic defocus in the evening was significantly more effective at inhibiting eye growth than in the morning ("2-hr lens-wear": X-C: -149 vs -83 μm/5d; "2-hr lens-removal": X-C: 91 vs 245 μm/7d; post-hoc Bonferroni test, p choroidal rhythm, there was no effect on phase, however, the amplitude was larger in most, but not all, experimental groups. These findings have potential translational applications to myopia prevention in schoolchildren, who are exposed to extended periods of hyperopic defocus during reading sessions, due to the nearness of the page. We propose that bouts of such

  11. Mesoscale structure of a morning sector ionospheric shear flow region determined by conjugate Cluster II and MIRACLE ground-based observations

    Directory of Open Access Journals (Sweden)

    O. Amm

    Full Text Available We analyse a conjunction event of the Cluster II spacecraft with the MIRACLE ground-based instrument net-work in northern Fennoscandia on 6 February 2001, between 23:00 and 00:00 UT. Shortly after the spacecraft were located at perigee, the Cluster II satellites’ magnetic footpoints move northwards over Scandinavia and Svalbard, almost perfectly aligned with the central chain of the IMAGE magnetometer network, and cross a morning sector ionospheric shear zone during this passage. In this study we focus on the mesoscale structure of the ionosphere. Ionospheric conductances, true horizontal currents, and field-aligned currents (FAC are calculated from the ground-based measurements of the IMAGE magnetometers and the STARE coherent scatter radar, using the 1-D method of characteristics. An excellent agreement between these results and the FAC observed by Cluster II is reached after averaging the Cluster measurements to mesoscales, as well as between the location of the convection reversal boundary (CRB, as observed by STARE and by the Cluster II EFW instrument. A sheet of downward FAC is observed in the vicinity of the CRB, which is mainly caused by the positive divergence of the electric field there. This FAC sheet is detached by 0.5°–2° of latitude from a more equatorward downward FAC sheet at the poleward flank of the westward electrojet. This latter FAC sheet, as well as the upward FAC at the equatorward flank of the jet, are mainly caused by meridional gradients in the ionospheric conductances, which reach up to 25 S in the electrojet region, but only ~ 5 S poleward of it, with a minimum at the CRB. Particle measurements show that the major part of the downward FAC is carried by upward flowing electrons, and only a small part by downward flowing ions. The open-closed field line boundary is found to be located 3°–4° poleward of the CRB, implying significant errors if the latter is used as a proxy of the former.

    Key words

  12. Comparing Neonatal Outcome Following the Use of Ondansetron versus Vitamin B6 in Pregnant Females with Morning Sickness: A Randomized Clinical Trial

    Directory of Open Access Journals (Sweden)

    Shahraki

    2016-09-01

    Full Text Available Background Pregnancy-related nausea and vomiting or morning sickness with an overall prevalence rate of 80% is commonly appeared at the eighth week and frequently disappeared in most pregnant females at the 16th week of gestation. The severe form of the condition named hyperemesis occurs in one per 200 to 300 pregnancies; it is accompanied by dehydration, electrolyte instability and nutritional deficits and needs medical interventions. Limited data are available on harmful effects of common antiemetic medications used within pregnancy on human neonates. Objectives The current study aimed to compare the effects of ondansetron and vitamin B6 on neonatal outcome in pregnant females with pregnancy-related nausea and vomiting. Neonatal outcome included the probable difference in neonates’ gestational age, weight, height, head circumference and frequency of apparent congenital anomalies. Methods This randomized double-blinded clinical trial was conducted on 188 primipara singleton pregnant females with pregnancy-related nausea and vomiting who referred to state healthcare centers of Zabol, Iran, in 2014. The pregnant females were randomly assigned to receive drug packages including ondansetron tablets (4 mg or vitamin B6 tablets (40 mg and patients were instructed to take one tablet twice daily. Females were followed up until delivery and neonatal outcomes including any congenital anomaly, weight, height and head circumference at birth were assessed. Results There was no difference between the groups in the mean age of mother and the mean age of gestation. No differences were found between the groups regarding birth weight (3006.93 ± 441.86 versus 2949.65 ± 457.36 g, P= 0.67, height at birth (49.50 ± 1.45 versus 48.97 ± 1.47 cm, P= 0.75 and head circumference at birth (34.23 ± 1.22 versus 33.88 ± 1.26 cm, P = 0.56. No neonatal anomaly was observed in the two groups. Conclusions No significant differences were observed between the groups based

  13. National medalist

    Science.gov (United States)

    President Clinton has chosen eight prominent American scientists to receive the 1994 National Medal of Science, the nation's highest scientific honor. Frank Press, an AGU member and geophysicist at the Carnegie Institution of Washington, numbers among the eight science medalists who will receive their medals in October, according to an announcement last week by Jack Gibbons, assistant to the president for science and technology. The president chose the other seven recipients from the fields of structural engineering, organic photochemistry, theoretical physics, biology, computer science, sociology, and biochemistry.

  14. Zoom on Electricity | Gros plan sur l’électricité

    Directory of Open Access Journals (Sweden)

    2012-05-01

    Full Text Available Share of Renewables in Electricity Generation in the World (in GWhPart de la production d’électricité à partir d’énergies renouvelables dans le monde (en GWh­Electricity Generation (in TWh, 2008Production d’électricité (en TWh, 2008* Fossils: oil, gas, coal | Energies fossiles : pétrole, gaz, charbon. ** Renewables: hydro power, biomass, wind, solar, geothermal, sea power | Energies renouvelables : hydraulique, biomasse, éolien, solaire, géothermie, énergies marines.Source: Observatoire d...

  15. Examples from the Greenland-Project - Gentle Remediation Optiones (GROs) on Pb/zn Contaminated Sites

    Science.gov (United States)

    Friesl-Hanl, Wolfgang; Kidd, Petra; Siebielec, Grzegorz

    2017-04-01

    The GREENLAND-project brought together "best practice" examples of several field applied gentle remediation techniques (EUFP7-project "Gentle remediation of trace element-contaminated land - GREENLAND; www.greenland-project.eu) with 17 partners from 11 countries. Gentle remediation options (GRO) comprise environmentally friendly technologies that have little or no negative impact on the soil. The main technologies are • phytoextraction • in situ immobilization and • assisted phytostabilization. Mining and processing activities affecting many sites worldwide negatively. The huge amounts of moved and treated materials have led to considerable flows of wastes and emissions. Alongside the many advantages of processed ores to our society, adverse effects in nature and risks for the environment and human health are observed. Three stages of impact of Pb/Zn-ore-treatment on the environment are discussed here: (1) On sites where the ores are mined impacts are the result of crushing, grinding, concentrating activities, and where additionally parts of the installations remain after abandoning the mine, as well as by the massive amounts of remaining deposits or wastes (mine tailings). (2) On sites where smelting and processing takes place, depending on the process (Welz, Doerschel) different waste materials are deposited. The Welz process waste generally contains less Cd and Pb than the Doerschel process waste which additionally shows higher water- extractable metals. (3) On sites close to the emitting source metal contamination can be found in areas for housing, gardening, and agricultural use. Emissions consist mainly from oxides and sulfides (Zn, Cd), sulfates (Zn, Pb, and Cd), chlorides (Pb) and carbonates (Cd). All these wastes and emissions pose potential risks of dispersion of pollutants into the food chain due to erosion (wind, water), leaching and the transfer into feeding stuff and food crops. In-situ treatments have the potential for improving the situation on site and will be shown by means of field experiments in Spain, Poland and Austria. Keywords: Mining and smelting, in-situ remediation, phytomanagement, gentle remediation options

  16. Pineapple juice and its fractions in enzymatic browning inhibition of banana [Musa (AAA group) Gros Michel].

    Science.gov (United States)

    Chaisakdanugull, Chitsuda; Theerakulkait, Chockchai; Wrolstad, Ronald E

    2007-05-16

    The effectiveness of pineapple juice in enzymatic browning inhibition was evaluated on the cut surface of banana slices. After storage of banana slices at 15 degrees C for 3 days, pineapple juice showed browning inhibition to a similar extent as 8 mM ascorbic acid but less than 4 mM sodium metabisulfite. Fractionation of pineapple juice by a solid-phase C18 cartridge revealed that the directly eluted fraction (DE fraction) inhibited banana polyphenol oxidase (PPO) about 100% when compared to the control. The DE fraction also showed more inhibitory effect than 8 mM ascorbic acid in enzymatic browning inhibition of banana puree during storage at 5 degrees C for 24 h. Further identification of the DE fraction by fractionation with ion exchange chromatography and confirmation using model systems indicated that malic acid and citric acid play an important role in the enzymatic browning inhibition of banana PPO.

  17. Zoom on Electricity | Gros plan sur l’électricité

    OpenAIRE

    2012-01-01

    Share of Renewables in Electricity Generation in the World (in GWh) Part de la production d’électricité à partir d’énergies renouvelables dans le monde (en GWh) ­ Electricity Generation (in TWh, 2008) Production d’électricité (en TWh, 2008) * Fossils: oil, gas, coal | Energies fossiles : pétrole, gaz, charbon. ** Renewables: hydro power, biomass, wind, solar, geothermal, sea power | Energies renouvelables : hydraulique, biomasse, éolien, solaire, géothermie, énergies marines. Source: Observ...

  18. Reactivación socio-productiva : margen Torrent Gros (Mallorca)

    OpenAIRE

    Ezeiza Karrera, Irati

    2012-01-01

    Centro autogestionado de iniciativa social y utilidad pública para la integración socio-laboral basada en la formación teorico-práctica en agricultura ecológica, permacultura, gestión medioambiental, hostelería y autoconstrucción.

  19. Reactivación socio-productiva : margen Torrent Gros (Mallorca)

    OpenAIRE

    Ezeiza Karrera, Irati

    2012-01-01

    Centro autogestionado de iniciativa social y utilidad pública para la integración socio-laboral basada en la formación teorico-práctica en agricultura ecológica, permacultura, gestión medioambiental, hostelería y autoconstrucción.

  20. Sports Nation

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    China is working to become a global sports power International Olympic Committee President Jacques Rogge watched China’s 11th National Games at Jinan’s stadium in Shandong Province on October 16, 2009. His high-profile attendance has set the

  1. Nations Within.

    Science.gov (United States)

    Sheets, Rosa Hernandez

    1998-01-01

    Karen Gayton Swisher (Sioux), chair of teacher education at Haskell Indian Nations University (Kansas), discusses the history of American Indian education, its effects on Indian families and cultures, overcoming stereotypes, how teachers can teach Indian children more effectively, the importance of Indian interpretations of Indian education and…

  2. Happy Nation

    DEFF Research Database (Denmark)

    Baron, Christian

    Happy Nation er et stykke eksperimentel teknologiformidling, der er udformet som en skønlitterær roman. Værket tager udgangspunkt i et fremtidsscenarie, hvor virtual reality er blevet en hverdagsteknologi, hvis sansedel bliver understøttet af implantater, der kan foretage dyb hjernestimulation...

  3. Nations Within.

    Science.gov (United States)

    Sheets, Rosa Hernandez

    1998-01-01

    Karen Gayton Swisher (Sioux), chair of teacher education at Haskell Indian Nations University (Kansas), discusses the history of American Indian education, its effects on Indian families and cultures, overcoming stereotypes, how teachers can teach Indian children more effectively, the importance of Indian interpretations of Indian education and…

  4. 吉首市广场中老年人晨练现状调查研究%The Investigation on the Present Situation of the Middle Aged and Elderly Doing Morning Exercise in Jishou Squares

    Institute of Scientific and Technical Information of China (English)

    黄友德

    2014-01-01

    Through the understanding of the present situation that the middle aged and elderly do morning exercise in Jishou squares, the paper provides some helpful suggestions for relevant departments to strengthen physical exercises in the elderly. The study mainly uses questionnaire survey, which is mainly carried out from three parts: sex and age of the people who do morning exercise; the sport choice, the instruction choice and the time of morning exercise; the injury situations of the people who do morning exercise. The results show that: firstly, among the people who do morning exercise, female are obviously more than male; secondly, the persons who insist on doing morning exercise are always possessing strong exercise consciousness; thirdly, almost half of the people don't receive professional guidance, they mainly choose Wushu and Tai Chi to practice; fourthly, the parts that people damage focuses on leg knees, the main reason is that their understanding of the knowledge of sports injury is not enough and they are lack of professional guidance, full preparation activity and relaxation exercises, etc. This paper suggests that our city should build and perfect fitness management system and service system of the middle aged and elderly, digging more exercise programs, improving the self-protection consciousness of the people who do morning exercise, giving full play to the local physical institutions the radiation function, etc.%文章通过对吉首市广场中老年人晨练现状的了解,进而为有关部门加强中老年人体育锻炼提供一些有益的建议。研究主要采用问卷调查法,问卷从晨练者的性别、年龄,晨练的项目选择、接受指导、坚持时间以及运动损伤情况等三部分内容进行调查;研究结果表明:晨练者女性明显多于男性;晨练者的锻炼意识较强;一半的晨练者没有接受过专业指导,所练项目以武术、太极为最多;晨练者损伤的部位主要集中在

  5. ‘A MANHÃ É UMA ESPONJA’: UM ESTUDO SOBRE A ENGENHOSIDADE SEMÂNTICA The Morning is a Sponge: a Study on Semantic Ingenuity

    Directory of Open Access Journals (Sweden)

    Roberta Pires de Oliveira

    1997-08-01

    Full Text Available O meta-conceito 'metáfora' permite a elaboração de uma hipótese sobre a interpretação de metáforas inovadoras e sua relação com a engenhosidade semântica. Um proferimento é metafórico se, e somente se, ao mesmo tempo, um intérprete atribuir-lhe uma avaliação de ficcionalidade e sua interpretação se fizer através do procedimento semântico de projeção de predicados. Dada essa definição, o artigo procura mostrar que a interpretação de proferimentos metafóricos é função da presença simultânea de restrições advindas de diferentes lugares: restrições sintáticas, semânticas e pragmáticas. São essas restrições que balizam o procedimento de projeção de predicados. Ao final, defenderemos que nesse procedimento de projeção podemos reconhecer uma engenhosidade semântica, que não se confunde com a criatividade sintática tal qual é apresentada por Chomsky. A engenhosidade semântica pode ser melhor percebida na interpretação de metáforas inovadoras. Ela está, no entanto, presente na polissemia. Trata-se da capacidade de construir relações de similaridades.A definition of metaphor is presented in the first part of this paper. Roughly speaking, an utterance is metaphorical if at the same time it is judged to be fictional and its interpretation depends on projection. Such a definition allows the distinction between two types of utterances: conventional metaphors and living metaphors. For instance: ‘Maria é um anjo’ (Mary is an angel and ‘A manhã é uma esponja’ (The morning is a sponge, respectively. The second section proposes a description of the interpretation of living metaphors. It will be argued that there are several layers of constraints with respect to the interpretation of living metaphors. The paper ends presenting the hypothesis of a "semantic" creativity (ingenuity. It will be defended that parallel to a syntactic creativity we need a semantic creativity (ingenuity. Semantic creativity

  6. Nation branding and sustainable competitiveness of nations

    OpenAIRE

    2009-01-01

    Considering the importance of explaining how a nation brand is effectively managed and how nation branding aligns the nation's brand with country management so as to gain competitiveness, this research aims to assess the role of nation branding and to create a strategic management tool for nation branding to achieve sustainable competitiveness of nations. Focusing on performance in nation branding, the dissertation develops a brand management model towards a systematic and strategic applicati...

  7. National Development Generates National Identities

    Science.gov (United States)

    2016-01-01

    The purpose of the article is to test the relationship between national identities and modernisation. We test the hypotheses that not all forms of identity are equally compatible with modernisation as measured by Human Development Index. The less developed societies are characterised by strong ascribed national identities based on birth, territory and religion, but also by strong voluntarist identities based on civic features selected and/or achieved by an individual. While the former decreases with further modernisation, the latter may either decrease or remain at high levels and coexist with instrumental supranational identifications, typical for the most developed countries. The results, which are also confirmed by multilevel regression models, thus demonstrate that increasing modernisation in terms of development contributes to the shifts from classical, especially ascribed, identities towards instrumental identifications. These findings are particularly relevant in the turbulent times increasingly dominated by the hardly predictable effects of the recent mass migrations. PMID:26841050

  8. Study on prevalence rate and influencing factors of the early morning hy-pertension in the aged%老年人群清晨高血压患病率及影响因素分析

    Institute of Scientific and Technical Information of China (English)

    蒋巧巧; 王胜煌

    2015-01-01

    目的:了解老年人群清晨高血压患病率及相关影响因素。方法回顾性分析2012年7月~2013年12月在某中心60周岁以上老年健康体检人群,分析比较老年人群清晨高血压患病情况,以及性别、年龄、体重指数(BMI)、生活方式、患相关疾病、血糖、血脂对收缩压、舒张压的影响。结果老年人群清晨高血压总患病率20.1%,主要为轻中度高血压和单纯收缩期高血压为主,女性患病率明显高于男性,各组间比较差异有统计学意义(P0.05),建议在临床治疗清晨高血压中仍需强调以健康生活方式为基础,动态血压监测和信息化管理是清晨血压管理的有效新方式。%Objective To understand the early morning hypertension prevalence rate and related factors in the aged. Methods Retrospective analysis of ≥60 health examination in the aged from July 2012 to December 2013. statistics gender,age with prevalence rate in the early morning hypertension patients. multiple linear regression analysis gender,age, smoking, drinking, salt intake, exercise time, BMI, blood glucose, blood lipid,and diabetes or other relevant diseases effect on systolic blood pressure and diastolic blood pressure. Results The elderly morning hypertension preva-lence rate was 20.1%, most of them was mild-to-moderate hypertension,isolated systolic hypertension. The influence factors of systolic blood pressure were gender,age,high salt diet,smoking,blood glucose,TG,diabetes or other rel-evant diseases. The influence factors of diastolic blood pressure were gender, age, high salt diet, smoking, drinking,physical exercise,blood glucose, blood lipid and diabetesor other relevant diseases. Conclusion The influence factors of early morning hypertension were gender,age, high salt diet, smoking, drinking, physical exercise, blood glucose,blood lipid and diabetes or other relevant diseases. So treatment of early morning hypertension still insist on healthy

  9. Antihypertensive efficacy of telmisartan vs ramipril over the 24-h dosing period, including the critical early morning hours: a pooled analysis of the PRISMA I and II randomized trials.

    Science.gov (United States)

    Williams, B; Lacourcière, Y; Schumacher, H; Gosse, P; Neutel, J M

    2009-09-01

    Cardiovascular risk is subject to circadian variation, with peak morning incidence of myocardial infarction and stroke correlating with the early morning blood pressure (BP) surge (EMBPS). Ideally, antihypertensive therapy should maintain control of BP throughout the 24-h dosing cycle. In two sister studies, Prospective, Randomized Investigation of the Safety and efficacy of Micardis vs Ramipril Using ABPM (ambulatory BP monitoring) (PRISMA) I and II, BP control was compared in patients with essential hypertension (24-h mean baseline ambulatory BP approximately 148/93 mm Hg) randomized to the angiotensin receptor blocker, telmisartan (80 mg; n=802), or the angiotensin-converting enzyme inhibitor, ramipril (5 or 10 mg; n=811), both dosed in the morning. The primary end point was the change from baseline in mean ambulatory systolic BP (SBP) and diastolic BP (DBP) during the final 6 h of the 24-h dosing cycle. The adjusted mean treatment differences in the last 6-h mean ambulatory SBP/DBP were -5.8/-4.2 mm Hg after 8 weeks and -4.1/-3.0 mm Hg after 14 weeks, in favour of telmisartan (P<0.0001 for all four comparisons). Secondary end point results, including the mean 24-h ambulatory BP monitoring, day- and night-time BP and 24-h BP load, also significantly favoured telmisartan (P<0.0001). Both treatments were well tolerated; adverse events, including cough, were less common with telmisartan. These findings suggest that telmisartan is more effective than ramipril throughout the 24-h period and during the EMBPS; this may be attributable to telmisartan's long duration of effect, which is sustained throughout the 24-h dosing period.

  10. Nation branding and sustainable competitiveness of nations

    NARCIS (Netherlands)

    Lee, Kyung Mi

    2009-01-01

    Considering the importance of explaining how a nation brand is effectively managed and how nation branding aligns the nation's brand with country management so as to gain competitiveness, this research aims to assess the role of nation branding and to create a strategic management tool for nation

  11. Nation branding and sustainable competitiveness of nations

    NARCIS (Netherlands)

    Lee, Kyung Mi

    2009-01-01

    Considering the importance of explaining how a nation brand is effectively managed and how nation branding aligns the nation's brand with country management so as to gain competitiveness, this research aims to assess the role of nation branding and to create a strategic management tool for nation br

  12. Reduction of the morning blood pressure surge treated with olmesartan in Chinese patients with mild to moderate essential hypertension--a multicenter, open-label, single treatment group clinical study.

    Science.gov (United States)

    Jiao, Yuan; Ke, Yuannan; Sun, Ningling; Wang, Jiguang; Deng, Wude; Zhu, Junren

    2012-05-01

    To investigate the morning blood pressure surge (MBPS) in Chinese patients with mild to moderate essential hypertension treated with long-term administration of olmesartan, an angiotensin II receptor antagonist according to ambulatory blood pressure monitoring (ABPM). In a multi-center, prospective study, we investigated the long-term efficacy of olmesartan by ABPM in 18-75 years-old Chinese patients with mild to moderate hypertension (clinic diastolic blood pressure [DBP] 90-109 mm Hg and systolic blood pressure [SBP] olmesartan 20 mg once daily in the morning for 24 weeks. Ambulatory blood pressure monitoring was conducted at baseline and at the end of 24 weeks. At baseline, patients with an MBPS > or = 23 mmHg were classified as the MBPS group (n = 41), and all other patients were classified as the non-MBPS group (n = 46). The mean systolic and diastolic blood pressures (SBP/DBP) over 24 hours were reduced from 141.78 +/- 12.8/91.17 +/- 7.34 to 128.35 +/- 15.86/83.58 +/- 9.53 mmHg (p olmesartan were significantly different between the two groups (p Olmesartan effectively reduces blood pressure in patients with essential hypertension, and olmesartan especially reduces the MBPS in MBPS-prone patients.

  13. Application of fresh first morning midstream urine in cytological study of bladder cancer patients%晨起第一次新鲜中段尿用于膀胱癌细胞学诊断的临床价值

    Institute of Scientific and Technical Information of China (English)

    陈岳; 徐勇; 王锦; 刘冉录; 杨阔; 张昌文; 马宝杰; 张志宏; 乔宝民

    2010-01-01

    Objective To investigate the value of the application of the fresh first morning midstream urine in cytological study of bladder cancer patients. Methods The results of the fresh first and second morning midstream urine cytological studies for 52 bladder cancer patients were analyzed.Continual three urine samples and single urine sample were treated as study objects respectively. The positive rates in different tumor stages and grades were evaluated. Results The positive rate of overall 52 patients was 78. 8 % (41/52) in fresh first morning midstream urine and 80. 8% ( 42 / 52) in the fresh second morning midstream urine. While in 156 single urine samples, the positive percentages were 56.4%(88/156) and 60. 9% (95/156). The positive rates of the fresh first and second morning midstream urine were 69.7% (23/33) and 72.7% (24/33) respectively in grade 1- 2 patients, and 44.4 % (44/99) and 48. 5 % (48/99) in 99 single urine samples. The positive rates of 42 non-muscle invasive bladder cancer patients were 73. 8% (31/42) and 76.2% (32/42) in the fresh first and second morning midstream urine, while in 126 single urine samples, the positive rates were 54.8% (69/126)and 57.1% (72/126). There were no significant differences between positive rate of the fresh first and second morning midstream urine in diagnosis of bladder cancer, low grade bladder cancer and nonmuscle invasive bladder cancer. Conclusion The fresh first morning midstream urine can be used for urine cytological study in the diagnosis of bladder cancer, even in the diagnosis of low stage and low grade bladder cancer.%目的 探讨晨起第一次中段尿脱落细胞学检查诊断膀胱癌的临床价值. 方法 分析52例经活检或手术病理确诊为膀胱癌患者晨起第一、二次新鲜中段尿脱落细胞学检查结果,以连续3 d标本结果和单次标本结果为研究对象,按总体、病理分级及临床分期分别计算2个时段尿脱落细胞阳性率,并进行统计学分析.

  14. National Security and National Development: A Critique

    African Journals Online (AJOL)

    DR Nneka

    services, decayed and collapsed infrastructure, environmental degradation and socio ... Nigeria as a nation is reported to be blessed by enormous human and natural ... There has been the tendency right from independence to view national .... security is the protection of national survival, while Ray (1987) says that national.

  15. 老年原发性高血压患者晨峰与脉搏波传导速度相关性研究%Association between morning blood pressure surge and pulse wave velocity in elderly hypertensive subjects

    Institute of Scientific and Technical Information of China (English)

    胡小亮; 路方红; 刘振东; 赵颖馨; 孙尚文; 王舒健; 潘慧; 李俊

    2011-01-01

    目的 探讨老年高血压患者血压晨峰与颈桡动脉脉搏波传导速度(crPWV)的相关性.方法 选择老年原发性高血压患者159例,根据24 h动态血压结果,将患者分为晨峰组(95例)和非晨峰组(64例).2组行crPWV检测,并测血生化.结果 晨峰组crPWV明显高于非晨峰组[(11.5±1.7)m/s vs(9.1±1.6)m/s,P<0.01].crPWV与血压晨峰(r=0.787,P<0.01)、24 h收缩压(r=0.649,P<0.01)、年龄(r=0.437,P<0.01)、空腹血糖(r=0.293,P<0.05)及LDL-c(r=0.354,P<0.05)呈正相关;以crPWV为应变量,年龄、高血压病程、体重指数、空腹血糖、24 h收缩压及舒张压、LDL-C、TC、TG、HDL-C、血压晨峰为自变量,进行多元线性逐步回归分析,血压晨峰、24 h收缩压、年龄为crPWV独立影响因素.结论 血压晨峰与动脉粥样硬化密切相关.%objective To investigate the association between morning blood pressure (MBPS) and carotid-radial pulse wave velocity(crPWV) ,in elderly patients with essential hypertension. Method According to the results of 24 h ambulatory blood pressure monitoring, 159 patients were divided in to the morning surge group(MBPS group,n= 95) and non-morning blood pressure surge group(nMBPS group, n= 64). Carotid-radial pulse wave velocity, blood glucose and lipid profiles were recorded. Results The crPWV of the MBPS group was significantly higher than that of the nMBPS group[(11.5±1.7)m/s vs (9. 1±1. 6)m/s,P<0. 01]. Pearson relation analysis showed that crPWV level positively correlated with MBPS(r=0. 787,P<0. 01),the average of 24 h SBP (r=0. 649,P<0. 01) ,age(r=0. 437,P<0. 01),FPG(r=0. 293,P<0. 05) and LDL-C(r=0. 354, P<0. 05); Multiple linear regression showed that MBPS were significant and independent factors for crPWV in elderly patients with essential hypertension. Conclusion The study showed that MBPS was closely related with atherosclerosis in patients with essential hypertension,suggesting it is justified for concurrent inhibition of morning blood

  16. Early bronchodilator action of glycopyrronium versus tiotropium in moderate-to-severe COPD patients: a cross-over blinded randomized study (Symptoms and Pulmonary function in the moRnING

    Directory of Open Access Journals (Sweden)

    Marin JM

    2016-06-01

    Full Text Available Jose M Marin,1 Kai M Beeh,2 Andreas Clemens,3 Walter Castellani,4 Lennart Schaper,5 Dinesh Saralaya,6 Anthony Gunstone,7 Ricard Casamor,8 Konstantinos Kostikas,3 Maryam Aalamian-Mattheis3 1University Hospital Miguel Servet, IISAragón, CIBERES, Zaragoza, Spain; 2Insaf Respiratory Research Institute, Wiesbaden, Germany; 3Novartis Pharma AG, Basel, Switzerland; 4Hospital Piero Palagi, Fiorenze, Italy; 5Research Institute and Practice, Berlin-Brandenburg, Germany; 6Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK; 7Staploe Medical Center, Soham, Cambridge, UK; 8Novartis Farmaceutica SA, Barcelona, Spain Background: Morning symptoms associated with COPD have a negative impact on patients’ quality of life. Long-acting bronchodilators with rapid onset may relieve patients’ symptoms. In the Symptoms and Pulmonary function in the moRnING study, we prospectively compared the rapid onset bronchodilator profile of glycopyrronium (GLY and tiotropium (TIO during the first few hours after dosing in patients with moderate-to-severe COPD.Methods: Patients were randomized (1:1 to receive either once-daily GLY (50 µg or TIO (18 µg and corresponding placebos in a cross-over design for 28 days. The primary objective was to demonstrate the superiority of GLY versus TIO in area under the curve from 0 to 4 hours (AUC0-4h forced expiratory volume in 1 second (FEV1 after the first dose. The secondary objective was to compare GLY versus TIO using the patient reported outcomes Morning COPD Symptoms Questionnaire 3 hours post-inhalation.Results: One-hundred and twenty-six patients were randomized (male 70.2%; mean age 65.7 years and 108 patients completed the study. On Day 1, GLY resulted in significantly higher FEV1 AUC0-4h after the first dose versus TIO (treatment difference [Δ], 0.030 L, 95% confidence interval 0.004–0.056, P=0.025. Improvements in morning COPD symptoms from baseline at Days 1 and 28 were similar between GLY and TIO. Post hoc

  17. On the Writing Skills in the Novel-Morning Dozing Girl%浅析《上午打瞌睡的女孩》的写作技巧

    Institute of Scientific and Technical Information of China (English)

    肖艳平

    2011-01-01

    鬼子的中篇小说《上午打瞌睡的女孩》是他的“悲悯三部曲”之一。小说中内聚焦的叙事焦点、蒙太奇式的剪辑手法以及重复、隐喻、象征等写作技巧的运用,体现了作者的高明与高超之处。%Guizi's novella "morning dozing girl" is his "compassion trilogy" one. The use of the writing skills, such as focus on the narrative, montage-style editing techniques, repetition, symbols, reflecting the author's brilliant and superb place.

  18. Composition and abundance of fishes in the interface between open water and macrophyte banks, and the dynamics of this interface during morning and evening twilight, in lake Catalão, Amazonas, Brazil

    Directory of Open Access Journals (Sweden)

    Igor David da Costa

    2011-06-01

    Full Text Available This work studied the composition and abundance of the fishes that move between macrophyte banks and open water during the morning twilight (CM and afternoon twilight (CV. The collections were made using gillnets, along banks of Paspalum repens, at Catalão lake, in Amazonas, Brazil. A total of 222 individuals and 37 species were collected. Of these, 130 individuals were collected during the CM and 92 during the CV; 80 individuals were leaving during the CM and 40 individuals were leaving during the CV. Auchenipterus nuchalis, Pellona castelnaeana, Triportheus angulatus and T. albus were the most common and concentrated species collected in the CM and Pimelodus blochii was the most common species collected in the CV.

  19. National Emergency Communications Plan

    Science.gov (United States)

    2008-07-01

    Integration Center’s ( NIC ) Incident Management Systems Integration Division (IMSID) promotes plain- language standards and associated guidance. o Within...and Command and Control Centers Coordination Centers Lead Agency Supporting/Participating Departments and Agencies National Operations Center ( NOC ...National Guard Bureau NGO Nongovernmental Organization NIC National Integration Center NIEM National Information Exchange Model National Emergency

  20. 睡眠呼吸暂停相关心率变异与晨起血压的关联性研究%Relevance of sleep apnea-associated heart rate variability to morning blood pressure

    Institute of Scientific and Technical Information of China (English)

    徐清; 张劲农; 向敏; 付薇; 彭毅

    2009-01-01

    90% (DT90%), deviation between minimal heart rate and maximal heart rate during apnea (DHR) to systolic blood pressure (SBP), diastolic blood pressure (DBP), and mean arterial blood pressure (MAP) before and after sleep. Logistic regression was performed to examine the risk factors of morning diastolic hypertension and systolic hypertension. Moreover, odds ratio (OR) and 95% confidence interval (CI) of each risk factor were calculated. Results Morning SBP, DBP and MAP in 104 subjects were (128.3±17.9), (88.6± 10.6) and (101.8 ±12.3) mm Hg respectively. They were significantly elevated as compared with their pre-sleep levels [(123.5 ± 17.8),(82.0 ±9.6) and (95.8 ± 11.5) mm Hg respectively, all P<0.01]. Thirty-seven eases (35.6%)met the diagnostic criteria of hypertension (SBP≥140 and/or DBP≥90 mm Hg) in their blood pressures before sleep while 49 cases (47. 1%) in their morning blood pressures. Spearman's correlation analysis shows that DBP after sleep was correlated with DHR (r =0.214, P<0.05). DHR in OSAHS patients with diastolic hypertension increased as compared with those without diastolic hypertension (P < 0.05). After adjusting for age, BMI, AHI, nSaO2% rain and DT90%, DHR was a predictor for the morning systolic hypertension (OR = 1. 253, 95% CI: 1. 057 - 1. 486, P < 0. 01). Conclusions Sleep apnea-associated heart rate variability is correlated with morning DBP in OSAHS patients. And it is also an independent predictive factor for morning systolic hypertension. This suggests that vagal regulation may be involved in OSAHS associated hypertension.

  1. Correlation analysis between blood pressure morning peak of high-normal blood pressure and severity of coronary artery disease%正常高值血压者血压晨峰水平与冠状动脉病变程度的关系

    Institute of Scientific and Technical Information of China (English)

    郝翠平

    2015-01-01

    ObjectiveTo investigate the correlation between blood pressure morning peak of high-normal blood pressure and severity of coronary artery disease.Methods180 cases of patients with high-normal blood pressure in our hospital were given 24 h ambulatory blood pressure monitoring (ambulatory blood pressure monitoring, ABPM) and coronary angiography (coronary angiography, CAG). They were divided into morning peak group (67 cases) and non-morning peak group (113 cases) according to ABPM whether or not the morning peak phenomenon, ABPM, coronary artery lesions of two groups were compared, factors of coronary artery lesions were analyzed.ResultsThe morning peak group 24 h, day, night, morning peak systolic blood pressure were significantly higher than the average morning peak group (in turn, the value oft was 2.59, 3.46, 2.71, 11.89, allP<0.05); Coronary artery lesions of morning peak group of patients were significantly more than non-morning peak group (U=4.587 0,P<0.01); Gensini total score of morning peak group was significantly higher than the morning peak group (P<0.01); Multiple linear regression analysis showed that, MBPS, 24 h average systolic blood pressure, fasting glucose, age were independent risk factors for coronary artery disease.ConclusionThe high-normal blood pressure is closely related to MBPS severity of coronary artery disease, is an independent risk factor for coronary heart disease prediction and severity, effectively control blood pressure in patients with high-normal blood pressure can reduce morning peak target organ damage.%目的 探讨正常高值血压者血压晨峰水平与冠状动脉病变严重程度的相关性.方法 对我院收治的180例正常高值血压患者进行24 h动态血压监测(ABPM)以及冠状动脉造影(CAG).按ABPM有无晨峰现象分为晨峰组(67例)与非晨峰组(113例),比较两组患者的ABPM、冠状动脉病变支数,分析冠状动脉病变的影响因素.结果晨峰组白昼、夜间、24 h、晨峰平

  2. National Environmental Policy Act

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Environmental Policy Act (NEPA) was the first major environmental law in the United States and established national environmental policies for the...

  3. National Wetlands Inventory Polygons

    Data.gov (United States)

    Minnesota Department of Natural Resources — Wetland area features mapped as part of the National Wetlands Inventory (NWI). The National Wetlands Inventory is a national program sponsored by the US Fish and...

  4. National Convective Weather Diagnostic

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current convective hazards identified by the National Convective Weather Detection algorithm. The National Convective Weather Diagnostic (NCWD) is an automatically...

  5. National Wetlands Inventory Lines

    Data.gov (United States)

    Minnesota Department of Natural Resources — Linear wetland features (including selected streams, ditches, and narrow wetland bodies) mapped as part of the National Wetlands Inventory (NWI). The National...

  6. Sandia National Laboratories

    Data.gov (United States)

    Federal Laboratory Consortium — For more than 60 years, Sandia has delivered essential science and technology to resolve the nation's most challenging security issues.Sandia National Laboratories...

  7. National Airspace System Resources

    Data.gov (United States)

    Department of Transportation — National Airspace System Resources (NASR) maintains the national aeronautical information database, containing static data related to NAS facilities and operations....

  8. National Health Expenditure Data

    Data.gov (United States)

    U.S. Department of Health & Human Services — National Health Expenditure Accounts are comprised of the following, National Health Expenditures - Historical and Projected, Age Estimates, State Health...

  9. National identitet og kultursyn

    DEFF Research Database (Denmark)

    Lindhardt, Eva

    2013-01-01

    I kapitel bliver forholdet mellem nation, national identitet og nationalisme undersøgt med inddragelse af G. F. Herder og N.F.S. Grundtvigs syn på forholdet mellem kultur og nation samt en modstilling af det kulturelle og politiske medborgerskab. Herefter problematiseres begrebet nation med...

  10. qEMF3, a novel QTL for the early-morning flowering trait from wild rice, Oryza officinalis, to mitigate heat stress damage at flowering in rice, O. sativa.

    Science.gov (United States)

    Hirabayashi, Hideyuki; Sasaki, Kazuhiro; Kambe, Takashi; Gannaban, Ritchel B; Miras, Monaliza A; Mendioro, Merlyn S; Simon, Eliza V; Lumanglas, Patrick D; Fujita, Daisuke; Takemoto-Kuno, Yoko; Takeuchi, Yoshinobu; Kaji, Ryota; Kondo, Motohiko; Kobayashi, Nobuya; Ogawa, Tsugufumi; Ando, Ikuo; Jagadish, Krishna S V; Ishimaru, Tsutomu

    2015-03-01

    A decline in rice (Oryza sativa L.) production caused by heat stress is one of the biggest concerns resulting from future climate change. Rice spikelets are most susceptible to heat stress at flowering. The early-morning flowering (EMF) trait mitigates heat-induced spikelet sterility at the flowering stage by escaping heat stress during the daytime. We attempted to develop near-isogenic lines (NILs) for EMF in the indica-type genetic background by exploiting the EMF locus from wild rice, O. officinalis (CC genome). A stable quantitative trait locus (QTL) for flower opening time (FOT) was detected on chromosome 3. A QTL was designated as qEMF3 and it shifted FOT by 1.5-2.0 h earlier for cv. Nanjing 11 in temperate Japan and cv. IR64 in the Philippine tropics. NILs for EMF mitigated heat-induced spikelet sterility under elevated temperature conditions completing flower opening before reaching 35°C, a general threshold value leading to spikelet sterility. Quantification of FOT of cultivars popular in the tropics and subtropics did not reveal the EMF trait in any of the cultivars tested, suggesting that qEMF3 has the potential to advance FOT of currently popular cultivars to escape heat stress at flowering under future hotter climates. This is the first report to examine rice with the EMF trait through marker-assisted breeding using wild rice as a genetic resource.

  11. 妇科门诊短小手术不同时间段丙泊酚用量的比较%Comparison of propofol dosage in morning and at afternoon undergoing gynecological clinic short surgery

    Institute of Scientific and Technical Information of China (English)

    陈旭; 樊雅玲; 曾薇

    2016-01-01

    Objective To explore propofol dosage difference between in morning and at after-noon undergoing gynecological clinic short operation.Methods One thousands and nine hundred fifty eight female patients,aged 1 6-50 yr,of ASA physical status Ior II,undergoing gynecology clinic short operation,according to the operation time,were divided into two groups,Group morning (8:30-1 1:30,n =1047)and group afternoon (14:00-1 7:00,n =91 1).Each patient was intravenously injected fentanyl 0.01 μg/kg,and then propofol 2.5 mg/kg.When the observer’s assessment of alertness/se-dation (OAA/S)scores reached 0 score,the operation began.If the body moved,the surgery was stopped and 25 mg propofol was intravenously injected quickly.After 10 seconds observation,if the body movement existed,25 mg more propofol was performed,until the movement disappeared.Re-cord patients’year,height,weight,body mass index,and the heart beat,blood pressure of pre-op-eration,the number of times of cervix uteri expansion per vagina,the history of labor per vagina,the total dosage of propofol and the time length of sedation.Results The dosage of group afternoon (1 52.1 6±65.90)mg was higher than group morning’s (135.69±37.67)mg (P <0.05).There was no significant difference of time lengths of sedation between the two groups.Additional use of propofol in the afternoon group 387 (42.5%)was higher than group morning’s 1 99 (23.5%)(P <0.05).Conclusion In gynecological clinic short operation,the propofol dosage in afternoon was higher than that in the morning group.But the sedation time length in afternoon was not longer than that in the morning.%目的:探讨妇科门诊短小手术中上、下午丙泊酚用量是否存在差异。方法选择2012年10月~2015年5月妇科门诊手术患者1958例,年龄16~50岁,ASA Ⅰ或Ⅱ级,按手术时间分为上午组(8:30~11:30,n =1047)和下午组(14:00~17:00,n =911)。麻醉采用静脉注射芬太尼0.01μg/kg、丙泊酚2.5 mg/kg。

  12. 苦难中的人性异化——浅析鬼子小说《上午打瞌睡的女孩》%The Humanity Alienation in Suffering——Analysis of the Morning Dozing Girl

    Institute of Scientific and Technical Information of China (English)

    梁晗昱

    2012-01-01

    Guangxi's writer Guizi is good at describing the tragedy and suffering of nonentites in small environment.The Morning Dozing Girl shows the life of nonentites represented by Hanlu's family by distinctive writing technique and spiritual torture.The essay attempts to utilize the theory of alienation of Fromm to study the humanity alienation of individuals who survive in suffering.It also intends to seek the origin of humanity alienation and ponder over the humanity in suffering.%广西作家鬼子善于描写小环境中小人物的悲剧和苦难,《上午打瞌睡的女孩》以独特的写作手法和心灵拷问的方式展现了以寒露一家为代表的小人物的生存状况。本文试图运用佛洛姆的异化理论来探讨苦难夹缝中求生的个体是如何在人性异化道路上行走的,意在探求人性本真及人性异化的根源,思考苦难对人性的拷问。

  13. 4 C Theory and“Hercy Morning News” Distribution Marketing Strategy%4C 理论与《海西晨报》发行营销策略的构建

    Institute of Scientific and Technical Information of China (English)

    张涛

    2015-01-01

    从营销学看4C 营销理论,强调读者的中心地位,符合市场经济条件下报业经济发展的要求,4C营销理论对《海西晨报》社的发行营销策略具有重要启发。可以从生产读者欲求的报纸产品、降低读者满足阅读和购买需求的成本、提高读者阅读和购买报纸的方便程度、与读者加强沟通等四个方面进行设计和构想。%4C marketing theory emphasizes the central position of readers , to meet the requirements of the develop-ment of newspaper industry under the market economy condition .The 4C marketing theory has important inspiration to “Hercy Morning News” agency distribution marketing strategy .Specifically , it is from four aspects as issuing the newspaper for reader's desire , reducing reading cost , improving convenience of purchase , and strengthening com-munication with readers to design the marketing strategy .

  14. The story of a historic morning

    CERN Multimedia

    2008-01-01

    "To be invited to CERN and also to be involved in a historic moment is a career dream. It’s a place where everyone learns from each other and contributes their speciality to construct something unique that defies understanding." Trivan Pal, Paul Scherrer Institute "CERN is an organization of many challenges, it is difficult to represent its size and quality. Its achievements are stacked like Russian dolls in order to build a true giant." Attila Razc CERN, PH "CERN is more than a place of work. The scope of its projects and the zest of its personnel make it a place to work and to live." Pavel Tashev, Summer Student "The research happening here is such that it needs at least one or two years of a doctorate to grasp its ra...

  15. Infant salt preference and mother's morning sickness.

    Science.gov (United States)

    Crystal, S R; Bernstein, I L

    1998-06-01

    Evidence for an association between early pregnancy sickness and offspring salt (NaCl) preference has been obtained from studying offspring as young adults. To determine whether effects on NaCl preference are expressed in infancy, the present study examined 16-week-old infants whose mothers reported either little or no vomiting (N = 15) or frequent moderate to severe vomiting (N = 14) during the first 14 weeks of their pregnancy. The infants' oral-motor facial reactions to each solution and their relative intakes of distilled water and 0.1m and 0.2m NaCl were used as measures of preference. Infants of mothers who reported no or mild symptoms had a significantly lower relative intake of salt solutions than infants whose mothers reported moderate to severe symptoms (p < 0.01). The former infants also showed a greater number of aversive facial responses when given 0.2m NaCl (p < 0.05). Taken together, these findings support the hypothesis that maternal dehydration, induced by moderate to severe vomiting during pregnancy, can lead to enhanced salt preference in offspring. They also provide a potential explanation for some of the variability encountered when human infants are tested for their salt preference.

  16. Morning Sickness: Nausea and Vomiting of Pregnancy

    Science.gov (United States)

    ... be given to treat nausea and vomiting of pregnancy: Vitamin B 6 and doxylamine—Vitamin B 6 is ... early pregnancy, usually starting before 9 weeks of pregnancy. Nutrients: Nourishing substances supplied through food, such as vitamins and minerals. Thyroid Gland: A butterfly-shaped gland ...

  17. Morning Sickness: Nausea and Vomiting of Pregnancy

    Science.gov (United States)

    ... better if I have nausea and vomiting of pregnancy? Diet and lifestyle changes may help you feel better. You may ... there medical treatment for nausea and vomiting of pregnancy? If diet and lifestyle changes do not help your symptoms, or if ...

  18. National Farm Medicine Center

    Science.gov (United States)

    Research Areas Applied Sciences Biomedical Informatics Clinical Research Epidemiology Farm Medicine Human Genetics Oral-Systemic Health Clinical ... Consulting Agritourism Farm MAPPER Lyme Disease ROPS Rebate Zika Virus National Farm Medicine Center The National Farm ...

  19. National Toxicology Program

    Science.gov (United States)

    ... to Main Navigation Skip to Site Sidebar National Toxicology Program http://ntp.niehs.nih.gov Home Testing ... NTP Cell Phone Radiofrequency Radiation Studies The National Toxicology Program (NTP) has been conducting experiments in rats ...

  20. New Mexico National Cemeteries

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The United States Department of Veterans Affairs National Cemetery Administration maintains 2 national cemeteries in the state of New Mexico; the Fort Bayard...

  1. National Rehabilitation Information Center

    Science.gov (United States)

    ... including News and Notes) Welcome to the National Rehabilitation Information Center! We are conducting improvements to the ... experience. We apologize for any inconvenience The National Rehabilitation Information Center ( NARIC ) is the library of the ...

  2. National Vulvodynia Association

    Science.gov (United States)

    ... 20 years, the National Vulvodynia Association (NVA) , a nonprofit organization, has been dedicated to improving the health and ... of Use The National Vulvodynia Association is a nonprofit organization that strives to improve women's lives through education, ...

  3. Complications and Deaths - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — Complications and deaths - national data. This data set includes national-level data for the hip/knee complication measure, the Agency for Healthcare Research and...

  4. National Diabetes Education Program

    Science.gov (United States)

    ... Living Tips About WIN NIDDK Information Clearinghouses National Diabetes Education Program Together with more than 200 partners ... type 2 diabetes. Learn more about NDEP . National Diabetes Month You are the center of your diabetes ...

  5. Regional National Cooperative Observer

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA publication dedicated to issues, news and recognition of observers in the National Weather Service Cooperative Observer program. Issues published regionally...

  6. Heart Attack Payment - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — Payment for heart attack patients measure – national data. This data set includes national-level data for payments associated with a 30-day episode of care for heart...

  7. National Drug IQ Challenge

    Science.gov (United States)

    ... Reto nacional del coeficiente intelectual (CI) sobre las drogas y el alcohol 2016 National Drug IQ Challenge ... Reto nacional del coeficiente intelectual (CI) sobre las drogas y el alcohol 2015 National Drug IQ Challenge ...

  8. National Environmental Research Parks

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-01

    The National Environmental Research Parks are outdoor laboratories that provide opportunities for environmental studies on protected lands that act as buffers around Department of Energy (DOE) facilities. The research parks are used to evaluate the environmental consequences of energy use and development as well as the strategies to mitigate these effects. They are also used to demonstrate possible environmental and land-use options. The seven parks are: Fermilab National Environmental Research Park; Hanford National Environmental Research Park; Idaho National Environmental Research Park; Los Alamos National Environmental Research Park; Nevada National Environmental Research Park; Oak Ridge National Environmental Research Park; and Savannah River National Environmental Research Park. This document gives an overview of the events that led to the creation of the research parks. Its main purpose is to summarize key points about each park, including ecological research, geological characteristics, facilities, and available databases.

  9. National Register Historic Districts

    Data.gov (United States)

    Iowa State University GIS Support and Research Facility — The National Register Historic District layer is a shape file showing the boundaries of Historic Districts that are listed on the National Register of Historic Places.

  10. National Forest Boundaries

    Data.gov (United States)

    Minnesota Department of Natural Resources — This theme shows the USFS national forest boundaries in the state. This data was acquired from the GIS coordinators at both the Chippewa National Forest and the...

  11. National oceanographic information system

    Digital Repository Service at National Institute of Oceanography (India)

    Desai, B.N.; Kunte, P.D.; Bhargava, R.M.S.

    Ocean study is inherently interdisciplinary and therefore calls for a controlled and integrated approach for information generation, processing and decision making. In this context, Indian National Oceanographic Data Centre (INODC) of National...

  12. Patient survey (HCAHPS) - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — The national average for the HCAHPS survey categories. HCAHPS is a national, standardized survey of hospital patients about their experiences during a recent...

  13. National Emission Inventory (NEI)

    Data.gov (United States)

    U.S. Environmental Protection Agency — This data exchange allows states to submit data to the US Environmental Protection Agency's National Emissions Inventory (NEI). NEI is a national database of air...

  14. Prediction of National Wealth

    Science.gov (United States)

    Whetzel, Deborah L.; McDaniel, Michael A.

    2006-01-01

    In their book, IQ and the Wealth of Nations, Lynn and Vanhanen ([Lynn, R. and Vanhanen, T. (2002). IQ and the wealth of nations. Westport, CT: Praeger.]) proposed the hypothesis that "the intelligence of the populations has been a major factor responsible for the national differences in economic growth and for the gap in per capita income between…

  15. Gross National Happiness

    DEFF Research Database (Denmark)

    Giri, Krishna Prasad; Kjær-Rasmussen, Lone Krogh

    This paper investigates practices related to the ideology of infusing Gross National Happiness (GNH) into school curriculum, the effectiveness of the meditation and mind training and the implication of GNH for school environment. It also explores how GNH ambience has been managed and practiced...... of Gross National Happiness and Educating for Gross National happiness....

  16. Banal nationalism in practice

    DEFF Research Database (Denmark)

    Koefoed, Lasse Martin

    . The paper falls into four parts. First, I outline the problem in a broader European context. Second, the paper extends and elaborates on concepts such as everyday life nationalism, social poetics of the nation-state and banal nationalism. Third, the paper illustrates, on the basis of an interview analysis...

  17. National Stereotypes in Music

    NARCIS (Netherlands)

    Lajosi, K.

    2014-01-01

    Music became a marker of national identity in nineteenth-century Europe. Western art music consists of tonal systems that are universally intelligible, but certain rhythms and musical idioms have been associated with national styles. How, when, and why does a musical phrase or piece become national?

  18. 2015 National Nation-Level Geography Geodatabase

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The 2015 TIGER Geodatabases are extracts of selected nation based and state based geographic and cartographic information from the U.S. Census Bureau's Master...

  19. 代谢综合征患者血压晨峰与心脑血管事件的关系%Correlation between cardiovascular and cerebrovascular events and morning blood pressure surge in patients with metabolic syndrome

    Institute of Scientific and Technical Information of China (English)

    任春霖; 高学霞; 胡雪梅

    2012-01-01

    目的 探讨代谢综合征患者血压晨峰现象(MBPS)与心脑血管事件的相关性.方法 选择112例代谢综合征患者采用动态血压监测仪记录24 h血压,血压晨峰值≥35 mmHg患者为晨峰组(MBPS组)45例,血压晨峰值<35 mmHg患者为非晨峰组(NMBPS组)67例,两组均询问饮酒史、吸烟史、年龄、病程,测量诊室血压、身高、体重、计算体重指数(MBI),测定血糖、血脂,并对患者进行3年的随访.患者具备以下诊断标准为心脑血管事件:严重心律失常、急性冠脉综合征、缺血性脑血管病、出血性脑血管病,比较两组一般资料、动态血压各参数、心脑血管事件发生率.结果 与NMPBS组比较,MPBS组血压晨峰值、清晨平均动脉压、24 h平均收缩压、心脑血管事件发生率均明显升高,差异有统计学意义(P<0.05或P<0.01),晨峰组患者血压晨峰值与心脑血管事件发生率呈正相关.结论 代谢综合征患者血压晨峰与心脑血管事件发生密切相关,可能是心脑血管事件的独立危险因素.%Objective To investigate the correlation between cardiovascular and cerebrovascular events and morning blood pressure surge( MBPS ) in patients with metabolic syndrome. Methods A total of 112 patients with metabolic syndrome were divided into MB-PS group ( n = 45, MBPS ^ 35 mmHg ) and non-MBPS group( n = 67 , MBPS < 35 mmHg ) according to 24 h ambulatory blood pressure monitoring. All patients were investigated on drinking and smoking history, age, course of disease, blood pressure, height, weight, body mass index ( MBI ), glucose, blood lipid,and they were followed up for 3 years. General information, parameters of ambulatory blood pressure, incidence of cardiovascular and cerebrovascular events were compared between two groups. Results Compared with NMPBS group,MBPS,mean arterial pressure in the morning,24 h average systolic blood pressure,incidence of cardiovascular and cerebrovascular events in MBPS group

  20. Elites and popular nationalism.

    Science.gov (United States)

    Whitmeyer, Joseph M

    2002-09-01

    Much current theory concerning nationalism holds that elites commonly create or cause popular nationalism. In part, that thesis may be due to an overwhelming emphasis in research on nationalism on positive cases: cases where nationalism has appeared, ignoring cases where it has not. In this article, I challenge the thesis by showing numerous historical cases in which elites have promoted nationalisms that ordinary people have not adopted, or in which ordinary people have adopted a nationalism before it was taken up by elites. Even if elites do not create popular nationalism, however, they can and do shape its expression in a variety of ways, such as organizing it, providing relevant information, or providing opportunity or incentive for it. I show this through historical examples.

  1. Banal Nationalism in ESL Textbooks

    Science.gov (United States)

    Gulliver, Trevor

    2011-01-01

    Despite repeating claims that Canadians are less nationalistic than members of other nations, English as a second language (ESL) textbooks often participate in banal repetitions of nation-ness and nationalism. This banal nationalism takes the form of the marking of nation through flags, maps, routine deixis, and nationalized symbols. This study…

  2. Estudos de freqüência, morfologia e diagnóstico de Entamoeba gingivalis, Gros, 1849

    Directory of Open Access Journals (Sweden)

    Silvio Favoreto Junior

    1995-12-01

    Full Text Available Realizamos estudos de freqüência de Entamoeba gingivalis entre 100 pacientes atendidos nos ambulatórios odontológicos da Ufiiversidade Federal de Uberlândia (UFU, utilizando-se esfregaços corados pela técnica de Papanicolaou modificado, revelando um expressivo índice de 62% de positividade. A afinidade do corante pelo conteúdo vacuolarfagocítico impede uma nítida visualização das cromatinas central e periférica do núcleo do parasita. Lavados bucais de outros 10 pacientes foram utilizados para avaliar em qual método parasitológico de diagnóstico (a fresco e em coloração por hematoxilina férrica, Giemsa e Papanicolaou ocorre melhor visualização do parasita. O exame afresco do sedimento do lavado bucal revelou 100% de positividade e nítida visualização do parasita. Nenhuma técnica de coloração dos esfregaços se mostrou adequada, apresentando o núcleo freqüentemente mascarado pelos vacúolos fagocíticos. Em preparações coradas por azul de toluidina e na microscopia eletrônica de transmissão pode-se observar caracteres morfológicos típicos do protozoário.Entamoeba gingivalis is found only in its trophozoite form and it is postulated that its main transmission mechanism is through the kiss. E. gingivalis is considered pathogenic by some authors and commensal to others. It does not have a defined role in the installation of disease. To address some of this questions we studied a 100 patients who were seen through the Odontological Hospital from the Universidade Federal de Uberlândia in order to determine its frequency in the buccal cavity. The material were collected using swabs from four different buccal sites and the smears were stained by a modified Papanicolaou technique. The results revealed positivity index of 62%. The affinity of the dye to the food vacuole contents and to the ingested bactérias prevents clear visualisation of the central and peripherical chromatin constituents of the parasite's nucleus. Mouth washes with 3ml of saline from 10 patients, were used to evaluate which parasitological method of diagnosis (fresh, iron-haematoxylin stained, Giemsa and Papanicolaou gives better visualisation of the parasite. The mouth washes sediment from fresh material revealed 100% of positivity and clear visualisation of the free form and locomotion of the trophozoites. No stained technique of the smear showed adequate visualisation, presenting the nucleus partially covered by the food vacuoles. In stained preparations by toluidine blue ultrastructure analysis of the morphology of parasite can be obsewed.

  3. Estudos de freqüência, morfologia e diagnóstico de Entamoeba gingivalis, Gros, 1849

    Directory of Open Access Journals (Sweden)

    Silvio Favoreto Junior

    1995-12-01

    Full Text Available Realizamos estudos de freqüência de Entamoeba gingivalis entre 100 pacientes atendidos nos ambulatórios odontológicos da Ufiiversidade Federal de Uberlândia (UFU, utilizando-se esfregaços corados pela técnica de Papanicolaou modificado, revelando um expressivo índice de 62% de positividade. A afinidade do corante pelo conteúdo vacuolarfagocítico impede uma nítida visualização das cromatinas central e periférica do núcleo do parasita. Lavados bucais de outros 10 pacientes foram utilizados para avaliar em qual método parasitológico de diagnóstico (a fresco e em coloração por hematoxilina férrica, Giemsa e Papanicolaou ocorre melhor visualização do parasita. O exame afresco do sedimento do lavado bucal revelou 100% de positividade e nítida visualização do parasita. Nenhuma técnica de coloração dos esfregaços se mostrou adequada, apresentando o núcleo freqüentemente mascarado pelos vacúolos fagocíticos. Em preparações coradas por azul de toluidina e na microscopia eletrônica de transmissão pode-se observar caracteres morfológicos típicos do protozoário.

  4. Comparison of steady-state plasma concentrations of armodafinil and modafinil late in the day following morning administration: post hoc analysis of two randomized, double-blind, placebo-controlled, multiple-dose studies in healthy male subjects.

    Science.gov (United States)

    Darwish, Mona; Kirby, Mary; Hellriegel, Edward T

    2009-01-01

    Armodafinil, the R- and longer-lasting isomer of modafinil, may maintain higher plasma drug concentrations compared with racemic modafinil because of stereospecific differences in elimination of its isomers. This analysis set out to compare the steady-state pharmacokinetic profiles of armodafinil and modafinil on a milligram-to-milligram basis following once-daily administration. A post hoc analysis of two multiple-dose pharmacokinetic studies in healthy male subjects aged 18-50 years was conducted to compare dose-normalized (200 mg/day) plasma drug concentration and pharmacokinetic data for subjects in each study who completed 7 days of once-daily (morning) administration of armodafinil (n = 34) or modafinil (n = 18). Dose-normalized plasma concentrations of armodafinil on day 7 were higher than those of modafinil, with the greatest differences being observed later in the day. Across the 24-hour dose interval, plasma drug concentration fluctuation and swing were 28% and 42% less, respectively, with armodafinil than with modafinil. In addition, average late-day (3 pm to 7 pm after an 8 am dosing) plasma drug concentrations and partial values for the area under the plasma concentration versus time curve for 7-11 hours after dosing were both 44% higher with armodafinil. At steady state, armodafinil produces consistently higher plasma drug concentrations late in the day than modafinil when compared on a milligram-to-milligram basis. The distinct pharmacokinetic profile of armodafinil compared with that of the racemate may result in fundamentally different durations of action. These differences between the two medications cannot be made equivalent by increasing the dose of the racemate without introducing potential safety concerns.

  5. Metabolic and Physiological Characteristics of Novel Cultivars from Serpentinite Seep Fluids

    Science.gov (United States)

    Nelson, B.; Chowdhury, S.; Brazelton, W. J.; Schrenk, M. O.

    2011-12-01

    Subsurface waters associated with the alteration of ultramafic rocks become highly reducing and alkaline through a process known as serpentinization. As habitat, these fluids are in many ways metabolically constraining but can provide sufficient energy for chemolithotrophy. As part of an ongoing effort to characterize these communities, heterotrophic enrichment cultures and anaerobic microcosms were initiated with alkaline waters found at three geographically and geochemically distinct sites of active serpentinization. These include the Northern Apennine ophiolite in the Ligurian region of Italy, the Tablelands ophiolite at Gros Morne National Park, Canada and the Coast Range ophiolite at McLaughlin Natural Reserve, California. Enrichment cultures at pH 11 yielded numerous isolates related to Proteobacteria and Firmicutes, some of which are closely related to other cultivars from high pH and subsurface environments. Anaerobic water samples were amended with combinations of electron donors (hydrogen, complex organics, acetate) and acceptors (ferric iron, sulfate) in a block design. After several weeks of incubation, DNA was extracted from cell concentrations and community differences were compared by TRFLP. Of particular interest is the isolation of a putative iron reducing Firmicute from samples enriched with complex organic compounds and ferric citrate. Ongoing studies are aimed at characterizing the physiology of these isolates. These data provide important insights into the metabolic potential of serpentinite subsurface ecosystems, and are a complement to culture-independent genomic analyses.

  6. Effect of different drug administration time on blood pressure circadian rhythm and morning blood pressure of non dipper type dosing in elderly hypertensive%不同给药时间对非杓型老年高血压患者血压昼夜节律及清晨血压的影响

    Institute of Scientific and Technical Information of China (English)

    于淼; 李潞; 熊亦涵

    2013-01-01

    Objective To investigate effect of different drug administration time on blood pressure circadian rhythm and morning blood pressure of non dipper type dosing in elderly hypertensive. Methods 98 elderly non dipper hypertensive patients were selected , randomly divided into two groups, and were given amlodipine besylate 5mg for 12 weeks in the early morning and evening. Before and after treatment, two groups had monitored ambulatory blood pressure, recorded the mean blood pressure changes in day and night, calculated the percentage of circadian blood pressure difference, measured the early morning blood pressure with family self testing during, and calculated the morning blood pressure mean value and standard rate. Results After 12 weeks, the blood pressure circadian difference giving drug at night were higher than in the morning (P<0.05). No matter the family self testing early morning blood pressure in SBP or DBP, evening medication group were lower than control group in the morning, and the success rate was better (P<0.05). Conclusion Evening medication group adjusts better non dipper circadian rhythm of blood pressure in patients with essential hypertension in elderly patients and reduces the morning blood pressure.%目的:探讨不同给药时间对非杓型老年高血压患者血压昼夜节律及清晨血压的影响。方法入选非杓型老年高血压患者98例,随机分成两组,分别在清晨及晚上给予苯磺酸氨氯地平5 mg治疗12周,并于治疗前后进行24h动态血压监测,记录治疗前后两组白天、夜间平均血压变化,并计算出血压昼夜差值百分比,并于治疗期间通过家庭自测血压方法测量清晨血压,并计算出清晨血压平均值及达标率。结果12周后晚上服药组血压昼夜差值百分比高于清晨服药组(P<0.05),且家庭自测清晨血压无论是SBP还是DBP,晚上服药组均低于清晨服药组,且达标率较好(P<0.05)。结论晚上服药组能更好地调整非杓型老

  7. First Nations Power

    Energy Technology Data Exchange (ETDEWEB)

    Whitehead, K. [Whitby Hydro, ON (Canada)

    2002-07-01

    The partnership involving the First Nations of Southern First Nations Secretariat (SFNS) Economic Development Corporation and private sector companies is called First Nations Power (FNP), and is Aboriginal-owned. Business opportunities in the energy sector marketplace are being pursued through FNP. The member organizations of FNP are listed. Operating out of facilities located at Delaware First Nation in Moranviatown, Ontario, FNP utilizes strategic alliances with proven private sector firms and other First Nation organizations to advance its plans. FNP operates in the following fields: advisory services, energy management, transmission and grid connections, distribution and utility administration, retail of products and services, training and development, and power generation. The various projects include hydraulic and alternative energy sources. The business activities are briefly described, as are the energy projects and special projects. A discussion of the First Nations Power Team concludes this presentation.

  8. Nationalism and Crisis

    Directory of Open Access Journals (Sweden)

    Enrique Camacho

    2016-12-01

    Full Text Available Nationalism seems a persistent ideology in academia as much as in politics; despite the fact that it has been shown that nationalism is deeply unjust for minorities. A case for national identity is often invoked to supplement liberalism regarding the inner difficulties that liberal theories have to explain their membership, assure stability and produce endorsement. So it seems that national identity may  also be required for justice. While this controversy continues, I argue that a different approach is available. We can define a conception of legitimacy independently from a conception of justice, and then ask what legitimacy requires from our national allegiances. If everything goes well, much of the controversy from justice disappears as we find that the case for cultural nationalism may be illegitimate for liberal democracies.

  9. National HIV Testing Day

    Centers for Disease Control (CDC) Podcasts

    2011-06-09

    Dr. Kevin A. Fenton, Director of CDC's National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, discusses National HIV Testing Day, an annual observance which raises awareness of the importance of knowing one's HIV status and encourages at-risk individuals to get an HIV test.  Created: 6/9/2011 by National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention (NCHHSTP).   Date Released: 6/9/2011.

  10. National Center for Health Statistics

    Science.gov (United States)

    ... Submit Search The CDC National Center for Health Statistics Note: Javascript is disabled or is not supported ... Survey of Family Growth Vital Records National Vital Statistics System National Death Index Provider Surveys National Health ...

  11. National Aphasia Association

    Science.gov (United States)

    ... challenge. […] National Aphasia Association Response to Statements by Trump Campaign Spokesperson In response to a recent statement by Trump campaign spokesperson, Katrina Pierson, and the article which ...

  12. Performing Nation, Performing Difference

    DEFF Research Database (Denmark)

    Jensen, Lars

    , or nation building, on the one side and the stark historical realism of the stolen generations + the backdrop of the second world war bombing of Darwin by the Japanese collectively creates a number of interwoven narratives in the tapestry that forms Australian cultural history.......Baz Luhrmann's Australia is simultaneously a film made for an Australian and an international audience. One of the interesting question this raises is how Luhrmann performs the nation for the national and the international audience. The film's juxtaposition of the national epic of pioneering...

  13. Feasibility Analysis on Square Dancing as Morning Exercises in Higher Colleges---Taking Jilin Normal University for example%广场舞作为高校早操的可行性分析--以吉林师范大学为例

    Institute of Scientific and Technical Information of China (English)

    郭言斌

    2015-01-01

    After the investigations and analysis on the development status of morning exercises,this paper has analyzed line dance as morning exercise in many ways,including the value of physical exercise,mental health,body sculpt and their adapta-bility,foundation of the students and teachers,site advantage and external environment.It concluded that square dancing as the morning exercise is feasible.%在对早操现状调查分析的基础上,分别从广场舞的体育锻炼价值、心理健康、塑造形体及其适应性;以及广场舞的广泛教师及学生基础、场地优势、外部环境等方面进行了分析论证。从而得出结论广场舞作为早操是可行的。

  14. “兴趣驱动”与高校体育专业早操相结合的研究%On the Combination of"Interest Drive"and the Morning Exercises of the Sports Specialty in Colleges and Universities

    Institute of Scientific and Technical Information of China (English)

    孙阳

    2015-01-01

    早操是高校课外体育活动的重要组成部分,是体育专业学生的一门必修课,所以,重视早操、组织好早操是非常必要的。本文通过对体育专业学生早操开展情况进行分析研究,并以“兴趣驱动”为核心,从宣传、组织、管理入手提出相应对策,旨在提高早操质量,找出适宜体育专业早操的最佳内容,组织形式和模式。%Morning exercises in colleges and universities is the important part of the extracurricular sports activities, physical education is a required course for students, so, it is very necessary to pay attention to exercise and organize the morning exercises. Through the analysis and research of the morning exercises of sports specialized students, and taking the "interest drive"as the core, from the publicity, organization and management, this article puts forward the corresponding countermeasures, aiming at improving the quality of physical education exercises, and finding the best content suitable for exercises, organization form and mode.

  15. Study On the Scientific Morning Exercise of the Students in the Institute of Physical Education--Taking the students of Nanjing Sports Institute as an example%体育类高校学生科学早操之对策研究--以南京体育学院学生早操现状分析

    Institute of Scientific and Technical Information of China (English)

    葛见珠; 李松骏

    2013-01-01

    Use the survey to understand the morning exercise status of Nanjing Sports Institute students. Through different angles of the managers and students, we look at the function and value of morning exercises and correct some wrong understanding and ideas from scientific point of view. We give some suggestions for improvement based on objective conditions. We hope that there will build a positive, continuous and scientific morning exercise regime in Sports Colleges and Universities.%运用调查法对南京体育学院学生早操现状进行了解,通过管理者和学生的不同角度审视早操的功能与价值,也从科学的角度纠正一些错误的认识和观念,并根据客观条件提出了针对性的改进建议,希望在体育院校及普通高校形成一种良性的、可持续性的、科学的早操制度。

  16. Action Plans for Improving BRT Passenger Flow during Morning and Afternoon Peak Hour in Guangzhou%广州市快速公交潮汐客流的应对措施

    Institute of Scientific and Technical Information of China (English)

    冼伟雄

    2011-01-01

    为有效应对广州市快速公交早晚高峰潮汐客流问题,通过客流调查、交通仿真、实车演练等方法寻求应对措施.首先,从系统模式、BRT通道和车站、客流情况几个方面介绍了广州市快速公交系统的概况.针对BRT潮汐客流问题开展客流调查,分析客流一般规律及车站客流分布.围绕动态借道、静态借位、灵活线路、始发分流、智能调度几项措施,分别探讨了具体方法及应用案例.分析结果表明,实施这些应对措施以后,公交车辆上下客时间控制在45 s内,公交运营速度提高84%,沿线市民搭乘公交出行的方便度和舒适度得到提高.最后,指出BRT试验线的不足,并从交通一体化角度提出发展快速公交的思路.%Aiming at moming and afternoon peak hours passenger flow of Bus Rapid Transit (BRT) in Guangzhou, this paper discusses the congestion countermeasures based on passenger survey, traffic simulation, and vehicle experiment. The paper first reviews Guangzhou BRT system in terms of the system structure, BRT corridors and stops,passenger flow, and etc. By analyzing the characteristics and distribution of passengers at each stop based on BRT passenger survey during morning and afternoon peak hours, the paper illustrates several specific measures and the action plans, such as reversible lanes, capacity reserve, flexible routes, traffic diverging, and intelligent scheduling. The analysis results show that the improvement plan results in a reduction in bus pick-up/drop-off time to less than 45 seconds and a 84% increase in bus travel speed, as well as an efficient and comfortable travel environment for bus travelers. Finally, the paper outlines the shortcomings of BRT pilot line and the integrated BRT development.

  17. Suvey of Acrylamide in Saled Morning Foods form Hefei%合肥市售早餐食品中丙烯酰胺含量状况调查

    Institute of Scientific and Technical Information of China (English)

    程坚; 程江华; 李钦; 王薇; 杨松; 赵成仕; 夏春

    2011-01-01

    [Objective]High performance liquid chromatography with tandem mass spectrometry (HPLC-MS-MS) of determination method was applied,and the acrylamide content of saled morning food was investigated. [Method] 11 varieties of food samples, 107 types which were often eaten by Hefei consumer from 8 breakfast restaurant were selected randomly and the foods were determined according to classifying and processing. [ Result ] Acrylamide in fried and frying starchy foods reached the highest level, among which twisted dough-strips acrylamide content reached 1 038 μg/kg,and acrylamide in cooking food wasn' t detected. [Conclusion] Relatively healthy processing methods such as cooking should be adopted,other unhealthy processing methods such as frying and baking should be avoided,so as to reduce breakfast food as possible in the intake of fried foods.%[目的]应用高效液相色谱串联质谱联用(HPLC-MS-MS)测定方法,对合肥市售早餐食品中丙烯酰胺含量状况进行调查.[方法]随机抽取合肥市8个早餐餐馆合肥市消费者经常食用的11个品种107份食品样品,将食物按种类和加工方式等分类后测定丙烯酰胺含量.[结果]油炸和油煎类淀粉类食物中丙烯酰胺含量最高,其中油条丙烯酰胺含量达1038μg/kg,蒸煮类食物基本未检出.[结论]食物加工应采用蒸煮等相对健康的加工方式,避免采用油炸烘烤等不健康加工方式,并且尽可能地减少早餐食品中油炸类食品的摄入.

  18. Simbolos Nacionales. National Symbols.

    Science.gov (United States)

    Toro, Leonor

    Written in Spanish and English, this booklet contains information on Puerto Rico's national symbols, including its anthem, emblem, and flag. Verses to "La Borinquena," the national anthem, are given , as well as the song's historical background and musical evolution, covering contributions of Felix Astol Artes, Paco Ramirez Ortiz, Lola Rodriques…

  19. Die Rhetorik der Nation

    DEFF Research Database (Denmark)

    Finsen, H.C.

    Nationens retorik. Bogen dokumenterer en fælleseuropæisk talekonvention mellem renæssance og romantik. Det vises, hvordan talen om nation og national identitet underlægges retoriske strategier som imitation og etos. Således bliver det muligt at beskrive en verbaliseringstradition, en ars nationis...

  20. Building National Healthcare Infrastructure

    DEFF Research Database (Denmark)

    Jensen, Tina Blegind; Thorseng, Anne

    2017-01-01

    This case chapter is about the evolution of the Danish national e-health portal, sundhed.dk, which provides patient-oriented digital services. We present how the organization behind sundhed.dk succeeded in establishing a national healthcare infrastructure by (1) collating and assembling existing ...

  1. Championing Developing Nations

    Institute of Scientific and Technical Information of China (English)

    Ni Yanshuo

    2011-01-01

    THE United Nations is without doubt the only organization that represents the interests of the entire world and being a member is essential for a country's credibility.That's why when South Sudan became independent recently,the new nation's first move was to join the UN,becoming the 193rd country to attain membership.

  2. TOP 10 NATIONAL EVENTS

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    1 Development Goals Defined China’s 12th Five-Year Plan for National Economic and Social Development (2011-15) was approved by the National People’s Congress, the country’s top legislature, on March 14. Focusing on building a green economy, China plans to cut energy consumption and carbon dioxide

  3. Building National Healthcare Infrastructure

    DEFF Research Database (Denmark)

    Jensen, Tina Blegind; Thorseng, Anne

    2017-01-01

    This case chapter is about the evolution of the Danish national e-health portal, sundhed.dk, which provides patient-oriented digital services. We present how the organization behind sundhed.dk succeeded in establishing a national healthcare infrastructure by (1) collating and assembling existing...

  4. Simbolos Nacionales. National Symbols.

    Science.gov (United States)

    Toro, Leonor

    Written in Spanish and English, this booklet contains information on Puerto Rico's national symbols, including its anthem, emblem, and flag. Verses to "La Borinquena," the national anthem, are given , as well as the song's historical background and musical evolution, covering contributions of Felix Astol Artes, Paco Ramirez Ortiz, Lola Rodriques…

  5. Elderhostel: A National Program.

    Science.gov (United States)

    O'Donnell, Kathleen M.; Berkeley, William D.

    1980-01-01

    Elderhostel, modeled on the youth hostels of Europe, is a national nonprofit organization offering older adults a week-long learning experience at any one of a national network of participating colleges and universities. The history and reasons for its success are described, along with a profile of its participants and an optimistic projection of…

  6. THE MAN NATIONALITY WOMEN

    Institute of Scientific and Technical Information of China (English)

    1997-01-01

    The Man nationality,with a population of 9,821,180,live in northeast China,mainly in Liaoning Province.They have their own language,but now most of the Man nationality people use Mandarin Chinese except for a few elderly people in the remote villages of Heilongjiang Province.

  7. Denmark's National Inventory Report

    DEFF Research Database (Denmark)

    Illerup, J. B.; Lyck, E.; Winther, M.

    This report is Denmark's National Inventory Report reported to the Conference of the Parties under the United Nations Framework Convention on Climate Change (UNFCCC) due by 15 April 2001. The report contains information on Denmark's inventories for all years' from 1990 to 1999 for CO2, CH4, N2O, CO...

  8. Denmark's National Inventory Report

    DEFF Research Database (Denmark)

    Illerup, J. B.; Lyck, E.; Winther, M.

    This report is Denmark's National Inventory Report reported to the Conference of the Parties under the United Nations Framework Convention on Climate Change (UNFCCC) due by 15 April 2001. The report contains information on Denmark's inventories for all years' from 1990 to 1999 for CO2, CH4, N2O, ...

  9. The Australian National University

    Institute of Scientific and Technical Information of China (English)

    李琳

    2007-01-01

    The Australian National University was established by Federal Parliament in 1946 with a mission to bring credit to the nation and to be one of the world’s great universities.It was the country’s only full-time research university at the time,and had no undergraduate teaching responsibilities.

  10. Denmark's National Inventory Report

    DEFF Research Database (Denmark)

    Illerup, J. B.; Lyck, E.; Winther, M.

    This report is Denmark's National Inventory Report reported to the Conference of the Parties under the United Nations Framework Convention on Climate Change (UNFCCC) due by 15 April 2001. The report contains information on Denmark's inventories for all years' from 1990 to 1999 for CO2, CH4, N2O, CO...

  11. National Tests and minorities

    DEFF Research Database (Denmark)

    Andreasen, Karen Egedal

    during the design of test materials (eg. Banks, 2009; Coronel-Molina & McCarthy, 2016). While initiatives have been taken to adapt national test practices to certain regional conditions, the dominant culture will continue to be imposed via both tests and national educational objectives observed...

  12. National Down Syndrome Society

    Science.gov (United States)

    ... DONATE HERE The ABLE Act is Now the Law of the Land! LEARN HOW TO PASS ABLE IN YOUR STATE! NDSS Your Way Join Our Independent Fundraising Program! The mission of the National Down Syndrome Society is to be the national advocate for the ...

  13. Value of care - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — Value of care displays – national data. This data set includes national-level data for the value of care displays associated with an episode of care for heart...

  14. Holy Nations. Global Identities

    DEFF Research Database (Denmark)

    Along with the processes of globalisation and the end of the cold war we have seen an upsurge in religious nationalism and an increasing focus on the role of religion as a legitimising force in democratic secular states. Holy Nations & Global Identities draws on the combined theoretical and histo......Along with the processes of globalisation and the end of the cold war we have seen an upsurge in religious nationalism and an increasing focus on the role of religion as a legitimising force in democratic secular states. Holy Nations & Global Identities draws on the combined theoretical...... and historical insight of historians, political scientists and social scientists on the question of nationalism and globalisation with the methodological knowledge of religion presented by sociologists of religion. The book brings genuine theoretical explorations and original case studies on civil religion...

  15. 睡眠呼吸暂停综合征与晨峰血压、心率关系的研究%Relationship of sleep apnea syndrome to morning blood pressure surge and heart rate variability

    Institute of Scientific and Technical Information of China (English)

    李莹; 闫明; 郭吉伟; 周泠淇; 徐斌; 邓丽华; 王观宇; 郑万斌

    2014-01-01

    Objective To investigate the relationship of sleep apnea syndrome to morning blood pressure surge and heart rate variability .Methods Sixty-four patients with obstructive sleep apnea syndrome ( OSAS) and essential hypertention underwent 24-hour ambulatory blood pressure monitoring (ABPM) and 24-hour Holter.According to ABPM, they were divided into two groups:the morning blood pressure surge group ( MBPS group ) included 33 patients and the non-MBPS group with 31.In addition, the control guoup consisted of 30 healthy persons at the same time.The parameters in sleep-breathing monitoring ,circadian rhythm of blood pressure and heart rate variability among the three groups were compared .Results Patients in MBPS group and non-MBPS group had higher apnea hypopnea index ( AHI, P0.05 ) . Conclusion Patients with MBPS have higher AHI and lower minimum blood oxygen saturation level , comprise more patients with non-dipper hypertention , suffer from more serious damage to autonomic nerves and are more prone to cardiac and cerebrovascular accident .%目的:探讨睡眠呼吸暂停综合征( obstructive sleep apnea syndrome , OSAS)与晨峰血压、心率变异性的关系。方法对64例检查明确为OSAS,且合并原发性高血压的患者行24 h动态血压监测和动态心电图监测,按OSAS合并高血压患者是否合并血压晨峰分为两组:OSAS合并高血压病伴血压晨峰组(晨峰组)33例,OSAS合并高血压病不伴血压晨峰组(非晨峰组)31例,以及同期健康体检人员30例作为对照组,比较3组睡眠呼吸监测结果及血压昼夜节律变化和心率变异性结果。结果晨峰组及非晨峰组和对照组比较,呼吸紊乱指数(AHI)增高(P<0.01),最低血氧饱和度降低(P<0.01),血压昼夜节律均有明显改变( P<0.01);晨峰组和非晨峰组比较,AHI、最低血氧饱和度和血压昼夜节律也有所不同,晨峰组AHI更高(P<0.05),最

  16. Imaging Near-Surface Controls on Hot Spring Expression Using Shallow Seismic Refraction in Yellowstone National Park

    Science.gov (United States)

    Price, A. N.; Lindsey, C.; Fairley, J. P., Jr.; Larson, P. B.

    2015-12-01

    We used shallow seismic refraction to image near-surface materials in the vicinity of a small group of hot springs, located in the Morning Mist Springs area of Lower Geyser Basin, Yellowstone National Park, Wyoming. Seismic velocities in the area surveyed range from a low of 0.3 km/s to a high of approximately 2.5 km/s. The survey results indicate an irregular surface topography overlain by silty sediments. The observed seismic velocities are consistent with a subsurface model in which sorted sands and gravels, probably outwash materials from the Pinedale glaciation, are overlain by silts and fine sands deposited in the flat-lying areas of the Morning Springs area. These findings are supported by published geologic maps of the area and well logs from a nearby borehole. The near-surface materials appear to be saturated with discharging hydrothermal fluids of varying temperature, and interbedded with semi-lithified geothermal deposits (sinter). We hypothesize that the relatively low-conductivity deposits of fines at the surface may serve to confine a shallow, relatively low-temperature (sub-boiling) hydrothermal aquifer, and that the distribution of sinter in the shallow subsurface plays an important role in determining the geometry of hydrothermal discharge (hot springs) at the land surface. Few studies of the shallow controls on hot spring expression exist for the Yellowstone caldera, and the present study therefore offers a unique glimpse into near-subsurface fluid flow controls.

  17. Public acceptance of management actions and judgments of responsibility for the wolves of the southern Greater Yellowstone Area: Report to Grand Teton National Park

    Science.gov (United States)

    Taylor, Jonathan G.; Johnson, S. Shea; Shelby, Lori B.

    2005-01-01

    Introduction Wolves of Grand Teton National Park and the Greater Yellowstone Area Gray wolves (Canis lupus) appeared in Grand Teton National Park (GRTE) in October of 1998, two years after being reintroduced to Yellowstone National Park (YNP). Since that time, five packs have been within the GRTE borders - Gros Ventre Pack, Nez Perce Pack, Yellowstone Delta Pack, Teton Pack, and Green River Pack (Table 1). Wolves in the Greater Yellowstone Area are increasing and spreading out geographically (USFWS and others, 2004). This dispersion was demonstrated recently by the death of a 2-year-old female wolf from the Swan Lake pack on I-70 in Colorado (June 7, 2004; http://mountain-prairie.USFWS.gov/pressrel /04-43.htm). The organization of wolf packs in the GYA is dynamic and highly structured. In 2003, for example, a wolf from the Teton Pack joined with the Green River Pack, and several young wolves left the Teton Pack and moved south (USFWS and others, 2004). Pack size (averaging five to ten members) is dependent on hunting efficiency, which depends on prey size, type, and density. Each pack defends home ranges of several hundred square miles. The social structure of the pack is based on a breeding pair (an alpha male and female). Other wolves in the pack can be categorized as betas (males and/or females second in rank to the alphas), subordinates, pups, and occasional omegas (outcasts). Because generally only the alpha pair breeds, subordinate wolves of reproductive age must disperse from their packs and form new associations in order to breed. (http://www.nps.gov/grte/wolf/biolo.htm). The reintroduced wolves are classified by the U.S. Fish and Wildlife Service (USFWS) as "nonessential experimental" under section 10(j) of the Endangered Species Act. The recovery criteria for the GYA wolves were met in 2002 for removing the wolves from the Endangered Species List (30 or more breeding pairs). Currently, the USFWS manages wolf populations in the GYA until delisting occurs

  18. Milestones for National Technical

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    The first session of National Technical Committee of Auto Standardization was established onApri128,1988. The first session of National Technical Committee of Auto Standardization (SAC/TC 114)was established in Beijing on April 28,1988,under the approval of the National Bureau of Standards at that time,with the official from China Association of Automobile Manufacturers as its director.It played a very impoorant role,not only in the unified management of auto standards but also in the technical work of the management of auto products.

  19. United nations Orchestra

    CERN Multimedia

    MusiClub

    MusiClub United nations Orchestra www.ungenevaorchestra.ch An organizing committee has taken the initiative to create an Orchestra of the united nations at Geneva. In the context of this initiative, musicians in the following categories are invited to become members of the Orchestra and the Association: Active or retired staff of International organizations in Geneva; Active or retired employees of Permanent Missions to the United Nations at Geneva; as well as children and spouses of the above persons. For enrolment or for additional information, please contact: un.orchestra@yahoo.com

  20. National 5 physics

    CERN Document Server

    Baillie, Arthur

    2013-01-01

    A full course textbook for the new National 5 Physics syllabus!. This book is designed to act as a valuable resource for pupils studying National 5. Physics. It provides a core text which adheres closely to the SQA syllabus, with. each section of the book matching a unit of the syllabus, and each chapter. corresponding to a content area. It is an ideal - and comprehensive - teaching and. learning resource for National 5 Physics. In addition to the core text, the book. contains a variety of special features: For Interest, Research Tasks, Activities, Questions, Worked Examples, and Consolidation

  1. National Geospatial Program

    Science.gov (United States)

    Carswell, William J.

    2011-01-01

    The National Geospatial Program (NGP; http://www.usgs.gov/ngpo/) satisfies the needs of customers by providing geospatial products and services that customers incorporate into their decisionmaking and operational activities. These products and services provide geospatial data that are organized and maintained in cost-effective ways and developed by working with partners and organizations whose activities align with those of the program. To accomplish its mission, the NGP— organizes, maintains, publishes, and disseminates the geospatial baseline of the Nation's topography, natural landscape, and manmade environment through The National Map

  2. Delmarva Fox Squirrel Census Report 1977 Blackwater National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Area time counts of the endangered Delmarva Peninsula Fox Squirrels and concurrently of Eastern Grey Squirrels were conducted in 1977 on several mornings during the...

  3. Outpatient Imaging Efficiency - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — Use of medical imaging - national data. These measures give you information about hospitals' use of medical imaging tests for outpatients. Examples of medical...

  4. National ART Success Rates

    Science.gov (United States)

    ... ART and Birth Defects ART and Autism 2013 Assisted Reproductive Technology National Summary Report Recommend on Facebook Tweet Share ... live-birth rate? [PDF - 1.37MB] Section 2: ART Cycles using fresh nondonor eggs or embryos What ...

  5. National Privacy Research Strategy

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — On July 1, NITRD released the National Privacy Research Strategy. Research agencies across government participated in the development of the strategy, reviewing...

  6. National Nursing Home Survey

    Science.gov (United States)

    The National Nursing Home Survey provides includes characteristics such as size of nursing home facilities, ownership, Medicare/Medicaid certification, occupancy rate, number of days of care provided, and expenses.

  7. National Convective Weather Forecast

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The NCWF is an automatically generated depiction of: (1) current convection and (2) extrapolated signficant current convection. It is a supplement to, but does NOT...

  8. National Stroke Association

    Science.gov (United States)

    ... Virginia Washington West Virginia Wisconsin Wyoming Go National Stroke Association Our mission is to reduce the incidence ... and support for all impacted by stroke. Understanding stroke and the recovery journey can be overwhelming, but ...

  9. National Outbreak Reporting System

    Data.gov (United States)

    U.S. Department of Health & Human Services — The National Outbreak Reporting System (NORS) is a web-based platform designed to support reporting to CDC by local, state, and territorial health departments in the...

  10. National Health Interview Survey

    Data.gov (United States)

    U.S. Department of Health & Human Services — The National Health Interview Survey (NHIS) is the principal source of information on the health of the civilian noninstitutionalized population of the United States...

  11. National Suicide Prevention Lifeline

    Science.gov (United States)

    ... Initiatives Best Practices Our Network Media Resources National Suicide Prevention Lifeline We can all help prevent suicide. ... About The Lifeline Anyone could be struggling with suicide. Find more specific resources below. I'm Struggling ...

  12. GUMTI NATIONAL PARK

    African Journals Online (AJOL)

    Osondu

    2012-10-10

    Oct 10, 2012 ... their territorial habitats in the Gashaka-Gumti National Park (GGNP) ... investigation, Geographical Information System (GIS), and statistical ... It is against this background that ..... to promote, preserve, enhance, protect and.

  13. Vigne des Nations

    CERN Multimedia

    2004-01-01

    Since 1995 the Vineyard of Nations has honoured an international organisation. On 7 May, Robert Cramer, the Council of State, removed leaves from the vine at the side of Robert Aymar, Director of CERN (1 paragraph)

  14. National Coastal Mapping Program

    Data.gov (United States)

    Army Corps of Engineers, Department of the Army, Department of Defense — The U. S. Army Corps of Engineers (USACE) National Coastal Mapping Program (NCMP) is designed to provide high-resolution elevation and imagery data along U.S....

  15. National Geochemical Database: Concentrate

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Geochemistry of concentrates from the National Geochemical Database. Primarily inorganic elemental concentrations, most samples are from the continental US and...

  16. National Geochemical Database: Soil

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Geochemical analysis of soil samples from the National Geochemical Database. Primarily inorganic elemental concentrations, most samples are from the continental US...

  17. National Geochemical Database: Sediment

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Geochemical analysis of sediment samples from the National Geochemical Database. Primarily inorganic elemental concentrations, most samples are of stream sediment in...

  18. Climatological Data National Summary

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The CDNS was published from 1950 - 1980. Monthly and annual editions contain summarized climatological information from the following publications: Local...

  19. 2015 Roads National Geodatabase

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The 2015 TIGER Geodatabases are extracts of selected nation based and state based geographic and cartographic information from the U.S. Census Bureau's Master...

  20. National Multiple Sclerosis Society

    Science.gov (United States)

    ... Join the Community Stay Informed Corporate Support National Multiple Sclerosis Society Meet the Challenge to end MS Give ... in MS Research November 2, 2016 View All Multiple Sclerosis News & Press View All Clinical Trial Alerts Every ...

  1. NAIP National Metadata

    Data.gov (United States)

    Farm Service Agency, Department of Agriculture — The NAIP National Metadata Map contains USGS Quarter Quad and NAIP Seamline boundaries for every year NAIP imagery has been collected. Clicking on the map also makes...

  2. National Suicide Prevention Lifeline

    Science.gov (United States)

    ... About Suicide Prevention We Can All Prevent Suicide Mental Health & Suicide Prevention Glossary Stories of Hope and Recovery Get Involved Participate Social Media Hub Promote National Suicide Prevention Month Providers & Professionals ...

  3. National Psoriasis Foundation

    Science.gov (United States)

    ... is treated in their countries. Previous Next National Psoriasis Foundation provides you with the help you need to best manage your psoriasis or psoriatic arthritis, while promoting research to find ...

  4. National Medical Association

    Science.gov (United States)

    ... Regional Meetings CME Fall Workshop Approved CME Activities Journal CME Quiz Online CME Submit an Abstract Faculty and Invited Speakers Policies and Procedures CME Resource Links Contact CME Resources Journal of the NMA Programs Overview Programmatic Initiatives National ...

  5. National Death Index

    Data.gov (United States)

    U.S. Department of Health & Human Services — The National Death Index (NDI) is a centralized database of death record information on file in state vital statistics offices. Working with these state offices, the...

  6. National Wetlands Inventory Points

    Data.gov (United States)

    Minnesota Department of Natural Resources — Wetland point features (typically wetlands that are too small to be as area features at the data scale) mapped as part of the National Wetlands Inventory (NWI). The...

  7. National Emission Inventory

    Data.gov (United States)

    U.S. Environmental Protection Agency — The National Emission Inventory contains measured, modeled, and estimated data for emissions of all known source categories in the US (stationary sources, fires,...

  8. MQSA National Statistics

    Science.gov (United States)

    ... Standards Act and Program MQSA Insights MQSA National Statistics Share Tweet Linkedin Pin it More sharing options ... but should level off with time. Archived Scorecard Statistics 2017 Scorecard Statistics 2016 Scorecard Statistics (Archived) 2015 ...

  9. 2015 Rails National Geodatabase

    Data.gov (United States)

    US Census Bureau, Department of Commerce — The 2015 TIGER Geodatabases are extracts of selected nation based and state based geographic and cartographic information from the U.S. Census Bureau's Master...

  10. National Geochemical Database: Sediment

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Geochemical analysis of sediment samples from the National Geochemical Database. Primarily inorganic elemental concentrations, most samples are of stream sediment...

  11. National Agriculture Imagery Program

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The National Agriculture Imagery Program (NAIP) acquires aerial imagery during the agricultural growing seasons in the continental U.S. A primary goal of the NAIP...

  12. National Assessment Database

    Data.gov (United States)

    U.S. Environmental Protection Agency — The National Assessment Database stores and tracks state water quality assessment decisions, Total Maximum Daily Loads (TMDLs) and other watershed plans designed to...

  13. National Military Family Association

    Science.gov (United States)

    ... 931.6632 info@MilitaryFamily.org © 2016 - National Military Family Association Twitter Facebook Pinterest Instagram Charity Navigator Four Star Charity GuideStar Exchange Better Business Bureau Charity Watch Independent Charity of America nonprofit ...

  14. National Elevation Dataset (NED)

    Data.gov (United States)

    Kansas Data Access and Support Center — The U.S. Geological Survey has developed a National Elevation Database (NED). The NED is a seamless mosaic of best-available elevation data. The 7.5-minute elevation...

  15. Healthcare Associated Infections - National

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Healthcare-Associated Infections (HAI) measures - national data. These measures are developed by Centers for Disease Control and Prevention (CDC) and...

  16. National Hydrography Dataset (NHD)

    Data.gov (United States)

    Kansas Data Access and Support Center — The National Hydrography Dataset (NHD) is a feature-based database that interconnects and uniquely identifies the stream segments or reaches that comprise the...

  17. Women of Jino Nationality

    Institute of Scientific and Technical Information of China (English)

    1996-01-01

    The dress of the Jino nationality differs greafiy from village to village. The upper photo shows the women of Xinyuan Village, Mengwang Township, with the photo on the right featuring women from Jiamazhai Village, Jino Township.

  18. US National Grid

    Data.gov (United States)

    Kansas Data Access and Support Center — This is a polygon feature data layer of United States National Grid (1000m x 1000m polygons ) constructed by the Center for Interdisciplinary Geospatial Information...

  19. National Bycatch Report (NBR)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This system collects bycatch data and fishery landings data from all five NOAA Fisheries Regions and automates the generation of the tables required to publish the...

  20. National Emission Inventory

    Data.gov (United States)

    U.S. Environmental Protection Agency — The National Emission Inventory contains measured, modeled, and estimated data for emissions of all known source categories in the US (stationary sources, fires,...