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Sample records for grism instrument igi

  1. Grism and immersion grating for space telescope

    Science.gov (United States)

    Ebizuka, Noboru; Oka, Kiko; Yamada, Akiko; Ishikawa, Mami; Kashiwagi, Masako; Kodate, Kashiko; Hirahara, Yasuhiro; Sato, Shuji; Kawabata, Koji S.; Wakaki, Moriaki; Morita, Shin-ya; Simizu, Tomoyuki; Yin, Shaohui; Omori, Hitoshi; Iye, Masanori

    2017-11-01

    The grism is a versatile dispersion element for an astronomical instrument ranging from ultraviolet to infrared. Major benefit of using a grism in a space application, instead of a reflection grating, is the size reduction of optical system because collimator and following optical elements could locate near by the grism. The surface relief (SR) grism is consisted a transmission grating and a prism, vertex angle of which is adjusted to redirect the diffracted beam straight along the direct vision direction at a specific order and wavelength. The volume phase holographic (VPH) grism consists a thick VPH grating sandwiched between two prisms, as specific order and wavelength is aligned the direct vision direction. The VPH grating inheres ideal diffraction efficiency on a higher dispersion application. On the other hand, the SR grating could achieve high diffraction efficiency on a lower dispersion application. Five grisms among eleven for the Faint Object Camera And Spectrograph (FOCAS) of the 8.2m Subaru Telescope with the resolving power from 250 to 3,000 are SR grisms fabricated by a replication method. Six additional grisms of FOCAS with the resolving power from 3,000 to 7,000 are VPH grisms. We propose "Quasi-Bragg grism" for a high dispersion spectroscopy with wide wavelength range. The germanium immersion grating for instance could reduce 1/64 as the total volume of a spectrograph with a conventional reflection grating since refractive index of germanium is over 4.0 from 1.6 to 20 μm. The prototype immersion gratings for the mid-InfraRed High dispersion Spectrograph (IRHS) are successfully fabricated by a nano-precision machine and grinding cup of cast iron with electrolytic dressing method.

  2. My IGY in Antarctica

    Science.gov (United States)

    Bentley, Charles

    2012-01-01

    Dr Charles Bentley is the A.P. Crary Professor Emeritus of Geophysics, Department of Geology and Geophysics, University of Wisconsin-Madison. Dr. Bentley joined the Arctic Institute of North America in 1956 to participate in International Geophysical Year (IGY)-related activities in the Antarctic. He wintered over consecutively in 1957 and 1958 at Byrd Station, a station in the interior of West Antarctica that housed 24 men each winter - 12 Navy support people and 12 civilian scientists/technicians. During the austral summers, he also participated in over-snow traverses, first as co-leader, then leader (the other coleader went home after the first year). These traverses consisted of six men and three vehicles, and lasted several months. These traverses covered more than 1609 kilometers (1000 miles) of largely unmapped and unphotographed terrain. During these traverses, connections to Byrd Station were by radio (daily, when the transmission conditions were good enough) and roughly every 2 weeks by resupply flight.

  3. Wayne—A Simulator for HST   WFC3 IR Grism Spectroscopy

    International Nuclear Information System (INIS)

    Varley, R.; Tsiaras, A.; Karpouzas, K.

    2017-01-01

    Wayne is an algorithm that simulates Hubble Space Telescope Wide Field Camera 3 (WFC3) grism spectroscopic frames, including sources of noise and systematics. It can simulate both staring and spatial scan modes, and observations such as the transit and the eclipse of an exoplanet. Unlike many other instrument simulators, the focus of Wayne is on creating frames with realistic systematics in order to test the effectiveness of different data analysis methods in a variety of different scenarios. This approach is critical for method validation and optimizing observing strategies. In this paper we describe the implementation of Wayne for WFC3 in the near-infrared channel with the G102 and G141 grisms. We compare the simulations to real data obtained for the exoplanet HD 209458b, to verify the accuracy of the simulation. The software is now available as open source at https://github.com/ucl-exoplanets/wayne.

  4. Wayne—A Simulator for HST   WFC3 IR Grism Spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Varley, R.; Tsiaras, A. [Department of Physics and Astronomy, University College London, Gower Street, WC1E6BT London (United Kingdom); Karpouzas, K., E-mail: r.varley@ucl.ac.uk [Department of Physics, Section of Astrophysics, Astronomy and Mechanics, Aristotle University of Thessaloniki, 541 24 Thessaloniki (Greece)

    2017-07-01

    Wayne is an algorithm that simulates Hubble Space Telescope Wide Field Camera 3 (WFC3) grism spectroscopic frames, including sources of noise and systematics. It can simulate both staring and spatial scan modes, and observations such as the transit and the eclipse of an exoplanet. Unlike many other instrument simulators, the focus of Wayne is on creating frames with realistic systematics in order to test the effectiveness of different data analysis methods in a variety of different scenarios. This approach is critical for method validation and optimizing observing strategies. In this paper we describe the implementation of Wayne for WFC3 in the near-infrared channel with the G102 and G141 grisms. We compare the simulations to real data obtained for the exoplanet HD 209458b, to verify the accuracy of the simulation. The software is now available as open source at https://github.com/ucl-exoplanets/wayne.

  5. EUCLID/NISP GRISM qualification model AIT/AIV campaign: optical, mechanical, thermal and vibration tests

    Science.gov (United States)

    Caillat, A.; Costille, A.; Pascal, S.; Rossin, C.; Vives, S.; Foulon, B.; Sanchez, P.

    2017-09-01

    Dark matter and dark energy mysteries will be explored by the Euclid ESA M-class space mission which will be launched in 2020. Millions of galaxies will be surveyed through visible imagery and NIR imagery and spectroscopy in order to map in three dimensions the Universe at different evolution stages over the past 10 billion years. The massive NIR spectroscopic survey will be done efficiently by the NISP instrument thanks to the use of grisms (for "Grating pRISMs") developed under the responsibility of the LAM. In this paper, we present the verification philosophy applied to test and validate each grism before the delivery to the project. The test sequence covers a large set of verifications: optical tests to validate efficiency and WFE of the component, mechanical tests to validate the robustness to vibration, thermal tests to validate its behavior in cryogenic environment and a complete metrology of the assembled component. We show the test results obtained on the first grism Engineering and Qualification Model (EQM) which will be delivered to the NISP project in fall 2016.

  6. First Results from Contamination Monitoring with the WFC3 UVIS G280 Grism

    Science.gov (United States)

    Rothberg, B.; Pirzkal, N.; Baggett, S.

    2011-11-01

    The presence of contaminants within the optical light path of the instrument or telescope can alter photometric zeropoints and the observed flux levels of imaging and spectra, particularly at UV wavelengths. Regular monitoring of a spectro-photometric standard star using photometric filters has been used in the past to monitor the presence of contaminants and (when necessary) re-calibrate zeropoints. However, the use of the WFC3 UVIS Grism mode (G280 filter) may provide a more robust early alert detection system for the presence of contaminants, in particular, those that are photo-polymerized from the bright Earth. These contaminants may collect on surfaces in the optical light path of the telescope. The G280 grism is sensitive to light at wavelengths below the cutoff of the bluest UV filter (F218W). In this ISR, we present: 1) the first results from G280 monitoring for the period of 2010-November through 2011-August; 2) the discovery of an anomaly in the WCS header information of sub-array exposures; and 3) an outline for reducing standard G280 grism observations and the specialized case of observations obtained in sub-array mode.

  7. The Hubble Legacy Archive ACS grism data

    Science.gov (United States)

    Kümmel, M.; Rosati, P.; Fosbury, R.; Haase, J.; Hook, R. N.; Kuntschner, H.; Lombardi, M.; Micol, A.; Nilsson, K. K.; Stoehr, F.; Walsh, J. R.

    2011-06-01

    A public release of slitless spectra, obtained with ACS/WFC and the G800L grism, is presented. Spectra were automatically extracted in a uniform way from 153 archival fields (or "associations") distributed across the two Galactic caps, covering all observations to 2008. The ACS G800L grism provides a wavelength range of 0.55-1.00 μm, with a dispersion of 40 Å/pixel and a resolution of ~80 Å for point-like sources. The ACS G800L images and matched direct images were reduced with an automatic pipeline that handles all steps from archive retrieval, alignment and astrometric calibration, direct image combination, catalogue generation, spectral extraction and collection of metadata. The large number of extracted spectra (73,581) demanded automatic methods for quality control and an automated classification algorithm was trained on the visual inspection of several thousand spectra. The final sample of quality controlled spectra includes 47 919 datasets (65% of the total number of extracted spectra) for 32 149 unique objects, with a median iAB-band magnitude of 23.7, reaching 26.5 AB for the faintest objects. Each released dataset contains science-ready 1D and 2D spectra, as well as multi-band image cutouts of corresponding sources and a useful preview page summarising the direct and slitless data, astrometric and photometric parameters. This release is part of the continuing effort to enhance the content of the Hubble Legacy Archive (HLA) with highly processed data products which significantly facilitate the scientific exploitation of the Hubble data. In order to characterize the slitless spectra, emission-line flux and equivalent width sensitivity of the ACS data were compared with public ground-based spectra in the GOODS-South field. An example list of emission line galaxies with two or more identified lines is also included, covering the redshift range 0.2 - 4.6. Almost all redshift determinations outside of the GOODS fields are new. The scope of science projects

  8. Updating the HST/ACS G800L Grism Calibration

    Science.gov (United States)

    Hathi, Nimish P.; Pirzkal, Norbert; Grogin, Norman A.; Chiaberge, Marco; ACS Team

    2018-06-01

    We present results from our ongoing work on obtaining newly derived trace and wavelength calibrations of the HST/ACS G800L grism and comparing them to previous set of calibrations. Past calibration efforts were based on 2003 observations. New observations of an emission line Wolf-Rayet star (WR96) were recently taken in HST Cycle 25 (PID: 15401). These observations are used to analyze and measure various grism properties, including wavelength calibration, spectral trace/tilt, length/size of grism orders, and spacing between various grism orders. To account for the field dependence, we observe WR96 at 3 different observing positions over the HST/ACS field of view. The three locations are the center of chip 1, the center of chip 2, and the center of the WFC1A-2K subarray (center of WFC Amp A on chip 1). This new data will help us to evaluate any differences in the G800L grism properties compared to previous calibration data, and to apply improved data analysis techniques to update these old measurements.

  9. Design and functional tests of the Euclid grism mount

    Science.gov (United States)

    Rossin, Ch.; Grange, R.; Caillat, A.; Costille, A.; Sanchez, P.; Ceria, W.

    2017-11-01

    The Euclid mission selected by ESA in the Cosmic Vision program is dedicated to understand dark energy and dark matter. One of the probes based on detection of Baryonic Acoustic Oscillations required the redshift of millions of galaxies. This massive spectroscopic survey relies on the Near Infrared SpectroPhotometer (NISP) using grism in slitless mode. In this Euclid NISP context, we designed a cryogenic mount for the four grisms of the spectroscopic channel. This mount has to maintain optical performances and alignment at the cryogenic temperature of 120K and to survive launch vibrations. Due to a very small mass and volume budget allowed in the Grism Wheel Assembly our design relies on a weight relief Invar ring glued to the grism by tangential flexures. Tangential flexures have the advantage of small height but the drawback of less decoupling capabilities than bipods. We will present the design of the mount and the integration and functional tests to stay within the 60 nm RMS transmitted wavefront error budget allowed to the grism.

  10. Optical verification tests of the NISP/Euclid grism qualification model

    Science.gov (United States)

    Caillat, Amandine; Costille, Anne; Pascal, Sandrine; Vives, Sébastien; Rossin, Christelle; Sanchez, Patrice; Foulon, Benjamin

    2016-07-01

    The Euclid space mission aims at elucidating dark matter and dark energy mysteries thanks to two scientific instruments: VIS, the visible camera and NISP, the Near Infrared Spectro-Photometer. Millions of galaxies spectra will be recorded thanks to its spectroscopic mode using four grisms developed under LAM (Laboratoire d'Astrophysique de Marseille) responsibility. These dispersive optical components are made of a grating on a prism and include also, specifically for NISP, three other optical functions: spectral filtering, focus adjustment and spectral wavefront correction. Therefore, these optical elements are very challenging to manufacture (four industrial partners work on a single optical component) and to test before integration into NISP. In this paper, first we describe the optical specifications and the manufacturing process. Second, we explain the optical validation tests campaign: optical setups, measurements and data processing procedures used to validate these complex optical components, particularly for transmitted efficiency and wavefront error for which specifications are very stringent. Finally, we present the first results obtained on the grism EQM which manufacturing is on-going and almost finished.

  11. Avian IgY antibodies: characteristics and applications in immunodiagnostic

    Directory of Open Access Journals (Sweden)

    Lívia Silveira Munhoz

    2014-01-01

    Full Text Available Immunoglobulin Y (IgY is the major antibody isotype in birds, reptiles, amphibia, and lungfish, playing a similar biological role as mammal IgG. Due to its phylogenetic distance, immune diversification and presence in the egg yolk, IgY provide a number of advantages in immunodiagnostic compared to IgG from mammals. Moreover, IgY production is in agreement with international efforts to reduce, refine and if possible, to replace animals in experimentation, contributing substantially in favor of animal welfare. This article presents an overview about structural and functional features, production and applications of IgY in immunodiagnostic, as well as the advantages of chicken antibodies use.

  12. Infrared Testing of the Wide-field Infrared Survey Telescope Grism Using Computer Generated Holograms

    Science.gov (United States)

    Dominguez, Margaret Z.; Content, David A.; Gong, Qian; Griesmann, Ulf; Hagopian, John G.; Marx, Catherine T; Whipple, Arthur L.

    2017-01-01

    Infrared Computer Generated Holograms (CGHs) were designed, manufactured and used to measure the performance of the grism (grating prism) prototype which includes testing Diffractive Optical Elements (DOE). The grism in the Wide Field Infrared Survey Telescope (WFIRST) will allow the surveying of a large section of the sky to find bright galaxies.

  13. PRODUKSI ANTIBODI KUNING TELUR (IGY ANTI STREPTOCOCCUS MUTANS SEBAGAI ANTI KARIES GIGI

    Directory of Open Access Journals (Sweden)

    Okti Nadia Poetri

    2006-12-01

    Full Text Available The aim of this study was to explore IgY anti Streptococcus mutan production and the ability of Igy Streptococcus mutans blocking adhesion process. The eggs was collected from Single Comb Brown Leghorn which have been immunized by S. mutan. Agar gel precipitation test was done to detect IgY anti S. mutans in serum and egg. Egg which Countain IgY anti S. mutans was collected. IgY anti S. mutans extracted from egg yolk by mean s PEG-Amonium sulfat and purified using fast protein liquid chromatography. The purity of Igy anti S. mutans was determined by UV spectropometer. Biological activities of Igy anti S. mutans to inhibit adhession process was learned by anti adhesion test. We use two dose of IgY, which is 100 ug and 500 ug. Igy anti S. mutans formen in serum five weeks after the first immunization while it formed in egg nine weeks after the first immunization. Igy anti S. mutanss still present in serum andegg until twelve weeks from the first immunization. Igy anti S. mutanss could decrease the amount of bacteria which attach the epithelial cell surface. The amount of sticky bacteria on epithelial cell (without IgY are 40 cell bacteria/epithelial cell. After blocked by IgY anti S. mutanss the amount of bacteria turn into 30 cell bacteria/epithelial cell (for dose of 100 ug IgY and 28 cell bacteria/epitheelial cell (for dose of 500 ug IgY. This research concluded that hens were capable producing IgY anti S. mutanss in egg yolk and it can be used to solve dental caries problem which caused by S. mutanss.

  14. IgY antibodies in human nutrition for disease prevention.

    Science.gov (United States)

    Müller, Sandra; Schubert, Andreas; Zajac, Julia; Dyck, Terry; Oelkrug, Christopher

    2015-10-20

    Oral administration of preformed specific antibodies is an attractive approach against infections of the digestive system in humans and animals in times of increasing antibiotic resistances. Previous studies showed a positive effect of egg yolk IgY antibodies on bacterial intoxications in animals and humans. Immunization of chickens with specific antigens offers the possibility to create various forms of antibodies. Research shows that orally applied IgY's isolated from egg yolks can passively cure or prevent diseases of the digestive system. The use of these alternative therapeutic drugs provides further advantages: (1) The production of IgY's is a non-invasive alternative to current methods; (2) The keeping of chickens is inexpensive; (3) The animals are easy to handle; (4) It avoids repetitive bleeding of laboratory animals; (5) It is also very cost effective regarding the high IgY concentration within the egg yolk. Novel targets of these antigen specific antibodies are Helicobacter pylori and also molecules involved in signaling pathways in gastric cancer. Furthermore, also dental caries causing bacteria like Streptococcus mutans or opportunistic Pseudomonas aeruginosa in cystic fibrosis patients are possible targets. Therefore, IgY's included in food for human consumption may be able to prevent or cure human diseases.

  15. HUBBLE SPACE TELESCOPE WFC3 EARLY RELEASE SCIENCE: EMISSION-LINE GALAXIES FROM INFRARED GRISM OBSERVATIONS

    International Nuclear Information System (INIS)

    Straughn, Amber N.; Gardner, Jonathan P.; Kuntschner, Harald; Kuemmel, Martin; Walsh, Jeremy R.; Cohen, Seth H.; Windhorst, Rogier A.; Malhotra, Sangeeta; Rhoads, James; O'Connell, Robert W.; Pirzkal, Norbert; Bond, Howard E.; Meurer, Gerhardt; McCarthy, Patrick J.; Hathi, Nimish P.; Balick, Bruce; Calzetti, Daniela; Disney, Michael J.; Dopita, Michael A.; Frogel, Jay A.

    2011-01-01

    We present grism spectra of emission-line galaxies (ELGs) from 0.6 to 1.6 μm from the Wide Field Camera 3 (WFC3) on the Hubble Space Telescope. These new infrared grism data augment previous optical Advanced Camera for Surveys G800L 0.6-0.95 μm grism data in GOODS-South from the PEARS program, extending the wavelength coverage well past the G800L red cutoff. The Early Release Science (ERS) grism field was observed at a depth of two orbits per grism, yielding spectra of hundreds of faint objects, a subset of which is presented here. ELGs are studied via the Hα, [O III], and [O II] emission lines detected in the redshift ranges 0.2 ∼ B(F098M) ≅ 25 mag. Seventeen GOODS-South galaxies that previously only had photometric redshifts now have new grism-spectroscopic redshifts, in some cases with large corrections to the photometric redshifts (Δz ≅ 0.3-0.5). Additionally, one galaxy had no previously measured redshift but now has a secure grism-spectroscopic redshift, for a total of 18 new GOODS-South spectroscopic redshifts. The faintest source in our sample has a magnitude m AB(F098M) = 26.9 mag. The ERS grism data also reflect the expected trend of lower specific star formation rates for the highest mass galaxies in the sample as a function of redshift, consistent with downsizing and discovered previously from large surveys. These results demonstrate the remarkable efficiency and capability of the WFC3 NIR grisms for measuring galaxy properties to faint magnitudes and redshifts to z ∼> 2.

  16. Parfocal wide field near infrared grism design and fabrication for WFIRST

    Data.gov (United States)

    National Aeronautics and Space Administration — WFIRST will have Hubble image quality with 100x the field area of HST/WFC3. It requires both imaging and, working in the same optical train, a grism allowing...

  17. A Lyman Break Galaxy in the Epoch of Reionization from Hubble Space Telescope (HST) Grism Spectroscopy

    Science.gov (United States)

    Rhoads, James E.; Malhotra, Sangeeta; Stern, Daniel K.; Gardner, Jonathan P.; Dickinson, Mark; Pirzkal, Norbert; Spinrad, Hyron; Reddy, Naveen; Dey, Arjun; Hathi, Nimish; hide

    2013-01-01

    Slitless grism spectroscopy from space offers dramatic advantages for studying high redshift galaxies: high spatial resolution to match the compact sizes of the targets, a dark and uniform sky background, and simultaneous observation over fields ranging from five square arcminutes (HST) to over 1000 square arcminutes (Euclid). Here we present observations of a galaxy at z = 6.57 the end of the reioinization epoch identified using slitless HST grism spectra from the PEARS survey (Probing Evolution And Reionization Spectroscopically) and reconfirmed with Keck + DEIMOS. This high redshift identification is enabled by the depth of the PEARS survey. Substantially higher redshifts are precluded for PEARS data by the declining sensitivity of the ACS grism at greater than lambda 0.95 micrometers. Spectra of Lyman breaks at yet higher redshifts will be possible using comparably deep observations with IR-sensitive grisms.

  18. Chronobiological studies of chicken IgY: monitoring of infradian, circadian and ultradian rhythms of IgY in blood and yolk of chickens.

    Science.gov (United States)

    He, Jin-Xin; Thirumalai, Diraviyam; Schade, Rüdiger; Zhang, Xiao-Ying

    2014-08-15

    IgY is the functional equivalent of mammalian IgG found in birds, reptiles and amphibians. Many of its biological aspects have been explored with different approaches. In order to evaluate the rhythmicity of serum and yolk IgY, four chickens were examined and reared under the same conditions. To monitor biological oscillations of IgY in yolk and serum, the eggs and blood samples were collected over a 60 day period and the rhythm of yolk and serum IgY was determined by direct-ELISA. Results indicated that, there is a significant circaseptan rhythm in yolk IgY and circaquattran rhythm in serum IgY. The serum IgY concentration reached a peak in the morning, decreased to a minimum during the daytime and increased again at night revealing a significant circadian rhythm was superimposed by an ultradian rhythm. These data are suited to address the controversies concerning the IgY concentration in egg yolk and blood of laying hens. In addition, this study raised new questions, if the different rhythms in yolk and serum are concerned. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Evaluation of the protective efficacy of immunoglobulin Y (IgY ...

    African Journals Online (AJOL)

    user

    2012-09-06

    Sep 6, 2012 ... IgY, which is transferred from serum to the yolk for ... The lethal potencies of the venom (LD50) were determined by i.p. injection of Swiss outbreed mice ... The protein concentration was measured by Biuret method and the. IgY-preparation ... Mean log10 antibody titer of the IgY- extracted by. Ammonium.

  20. Anti-Pseudomonas aeruginosa IgY antibodies augment bacterial clearance in a murine pneumonia model

    DEFF Research Database (Denmark)

    Thomsen, K.; Christophersen, L.; Bjarnsholt, T.

    2016-01-01

    Background: Oral prophylactic therapy by gargling with pathogen-specific egg yolk immunoglobulins (IgY) may reduce the initial airway colonization with Pseudomonas aeruginosa in cystic fibrosis (CF) patients. IgY antibodies impart passive immunization and we investigated the effects of anti......-P. aeruginosa IgY antibodies on bacterial eradication in a murine pneumonia model. Methods: P. aeruginosa pneumonia was established in Balb/c mice and the effects of prophylactic IgY administration on lung bacteriology, clinical parameters and subsequent inflammation were compared to controls. Results......: Prophylactic administration of IgY antibodies targeting P. aeruginosa significantly reduced the bacterial burden by 2-log 24 h post-infection compared to controls and was accompanied by significantly reduced clinical symptom scores and successive inflammatory cytokine profile indicative of diminished lung...

  1. PRODUKSI IGY SPESIFIK STAPHYLOCOCCUS AUREUS DARI ISOLAT ASAL KASUS STAPHYLOCOCCOSIS PADA KELINCI

    Directory of Open Access Journals (Sweden)

    Triwardhani Cahyaningsih

    2017-04-01

    Full Text Available This experiment aims to produce immunoglobulin Y (Ig-Y Staphylococcus aureus isolates origin staphylococcosis case in rabbits. Vaccination is done several times using Staphylococcus aureus active in 109 cfu/ml. Injecting the chicken is done four weeks in a row, the first week is done by intravenous injection of S. aureus antigens, the second week of the injection sub cutan S. aureus emulsified with Freund's complete adjuvant, followed by the third and fourth week of the injection of S. aureus antigen emulsified with incomplete Freund's adjuvant. Egg samples were taken after four weeks of the last injection for identification, purification, and determination of specific IgY against S. aureus in egg yolk. IgY specificity qualitatively tests performed by the AGP test (To Gel Precipitation. IgY extraction is done using PEG - Ammonium sulfate, purified IgY concentration calculated by the method of Bradford. The results showed that IgY began to be detected in egg yolk at week six after immunization, with the average levels of IgY is 1.7 mg/ml.

  2. Instrumentation

    International Nuclear Information System (INIS)

    Prieur, G.; Nadi, M.; Hedjiedj, A.; Weber, S.

    1995-01-01

    This second chapter on instrumentation gives little general consideration on history and classification of instrumentation, and two specific states of the art. The first one concerns NMR (block diagram of instrumentation chain with details on the magnets, gradients, probes, reception unit). The first one concerns precision instrumentation (optical fiber gyro-meter and scanning electron microscope), and its data processing tools (programmability, VXI standard and its history). The chapter ends with future trends on smart sensors and Field Emission Displays. (D.L.). Refs., figs

  3. Instrumentation

    International Nuclear Information System (INIS)

    Decreton, M.

    2000-01-01

    SCK-CEN's research and development programme on instrumentation aims at evaluating the potentials of new instrumentation technologies under the severe constraints of a nuclear application. It focuses on the tolerance of sensors to high radiation doses, including optical fibre sensors, and on the related intelligent data processing needed to cope with the nuclear constraints. Main achievements in these domains in 1999 are summarised

  4. Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Decreton, M

    2001-04-01

    SCK-CEN's research and development programme on instrumentation involves the assessment and the development of sensitive measurement systems used within a radiation environment. Particular emphasis is on the assessment of optical fibre components and their adaptability to radiation environments. The evaluation of ageing processes of instrumentation in fission plants, the development of specific data evaluation strategies to compensate for ageing induced degradation of sensors and cable performance form part of these activities. In 2000, particular emphasis was on in-core reactor instrumentation applied to fusion, accelerator driven and water-cooled fission reactors. This involved the development of high performance instrumentation for irradiation experiments in the BR2 reactor in support of new instrumentation needs for MYRRHA, and for diagnostic systems for the ITER reactor.

  5. Instrumentation

    International Nuclear Information System (INIS)

    Decreton, M.

    2001-01-01

    SCK-CEN's research and development programme on instrumentation involves the assessment and the development of sensitive measurement systems used within a radiation environment. Particular emphasis is on the assessment of optical fibre components and their adaptability to radiation environments. The evaluation of ageing processes of instrumentation in fission plants, the development of specific data evaluation strategies to compensate for ageing induced degradation of sensors and cable performance form part of these activities. In 2000, particular emphasis was on in-core reactor instrumentation applied to fusion, accelerator driven and water-cooled fission reactors. This involved the development of high performance instrumentation for irradiation experiments in the BR2 reactor in support of new instrumentation needs for MYRRHA, and for diagnostic systems for the ITER reactor

  6. Quantitative immunochemistry using IgG and IgY against plant ...

    African Journals Online (AJOL)

    Quantitative immunochemistry using IgG and IgY against plant hormones. ... both of animal origin, using chemical couplings to their respective functional groups. ... enzyme-linked immunosorbent assay; ELISA) to detect and quantify these ...

  7. Instrumentation

    International Nuclear Information System (INIS)

    Decreton, M.

    2002-01-01

    SCK-CEN's R and D programme on instrumentation involves the development of advanced instrumentation systems for nuclear applications as well as the assessment of the performance of these instruments in a radiation environment. Particular emphasis is on the use of optical fibres as umbilincal links of a remote handling unit for use during maintanance of a fusion reacor, studies on the radiation hardening of plasma diagnostic systems; investigations on new instrumentation for the future MYRRHA accelerator driven system; space applications related to radiation-hardened lenses; the development of new approaches for dose, temperature and strain measurements; the assessment of radiation-hardened sensors and motors for remote handling tasks and studies of dose measurement systems including the use of optical fibres. Progress and achievements in these areas for 2001 are described

  8. Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Decreton, M

    2002-04-01

    SCK-CEN's R and D programme on instrumentation involves the development of advanced instrumentation systems for nuclear applications as well as the assessment of the performance of these instruments in a radiation environment. Particular emphasis is on the use of optical fibres as umbilincal links of a remote handling unit for use during maintanance of a fusion reacor, studies on the radiation hardening of plasma diagnostic systems; investigations on new instrumentation for the future MYRRHA accelerator driven system; space applications related to radiation-hardened lenses; the development of new approaches for dose, temperature and strain measurements; the assessment of radiation-hardened sensors and motors for remote handling tasks and studies of dose measurement systems including the use of optical fibres. Progress and achievements in these areas for 2001 are described.

  9. Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Decreton, M

    2000-07-01

    SCK-CEN's research and development programme on instrumentation aims at evaluating the potentials of new instrumentation technologies under the severe constraints of a nuclear application. It focuses on the tolerance of sensors to high radiation doses, including optical fibre sensors, and on the related intelligent data processing needed to cope with the nuclear constraints. Main achievements in these domains in 1999 are summarised.

  10. Production and purification of IgY antibodies from chicken egg yolk

    Directory of Open Access Journals (Sweden)

    Wala Ahmad Amro

    2018-06-01

    Full Text Available The isolation of polyclonal antibodies from the serum of immunized mammals has significantly contributed to scientific research and diagnosis. The fact that recent technologies allow the production of antibodies in the yolk of eggs laid by hens, has led to the development of an alternative method for antibody generation that is less stressful to animals. As hens are kept under almost all their natural conditions, antibodies are isolated from the collected eggs; this technology is expected to become an interesting alternative to the conventionally serum-based techniques that eventually require to sacrifice the animal.Here we present a modified protocol for the isolation of IgY antibodies from immunized chickens and provide comparison between two chicken breeds in relative to IgY yield per egg. Our results show the possibility of generating large quantities of highly pure IgY from chicken eggs and also show large differences in the yield of IgY production between the two studied breeds. The results of this work indicate that IgY technology can be used for the production of primary antibodies for immunological work and disease diagnosis. Keywords: IgY, Chicken egg yolk, Gel filtration chromatography, Salmonella typhimurium

  11. Instrumentation

    International Nuclear Information System (INIS)

    Umminger, K.

    2008-01-01

    A proper measurement of the relevant single and two-phase flow parameters is the basis for the understanding of many complex thermal-hydraulic processes. Reliable instrumentation is therefore necessary for the interaction between analysis and experiment especially in the field of nuclear safety research where postulated accident scenarios have to be simulated in experimental facilities and predicted by complex computer code systems. The so-called conventional instrumentation for the measurement of e. g. pressures, temperatures, pressure differences and single phase flow velocities is still a solid basis for the investigation and interpretation of many phenomena and especially for the understanding of the overall system behavior. Measurement data from such instrumentation still serves in many cases as a database for thermal-hydraulic system codes. However some special instrumentation such as online concentration measurement for boric acid in the water phase or for non-condensibles in steam atmosphere as well as flow visualization techniques were further developed and successfully applied during the recent years. Concerning the modeling needs for advanced thermal-hydraulic codes, significant advances have been accomplished in the last few years in the local instrumentation technology for two-phase flow by the application of new sensor techniques, optical or beam methods and electronic technology. This paper will give insight into the current state of instrumentation technology for safety-related thermohydraulic experiments. Advantages and limitations of some measurement processes and systems will be indicated as well as trends and possibilities for further development. Aspects of instrumentation in operating reactors will also be mentioned.

  12. Instruments

    International Nuclear Information System (INIS)

    Buehrer, W.

    1996-01-01

    The present paper mediates a basic knowledge of the most commonly used experimental techniques. We discuss the principles and concepts necessary to understand what one is doing if one performs an experiment on a certain instrument. (author) 29 figs., 1 tab., refs

  13. Therapeutic potential of combined anti-IL-1β IgY and anti-TNF-α IgY in guinea pigs with allergic rhinitis induced by ovalbumin.

    Science.gov (United States)

    Guo-Zhu, Hu; Xi-Ling, Zhu; Zhu, Wen; Li-Hua, Wu; Dan, He; Xiao-Mu, Wu; Wen-Yun, Zhou; Wei-Xu, Hu

    2015-03-01

    We have previously demonstrated that anti-IL-1β immunoglobulin yolk(IgY) inhibits pathological responses in allergic asthma guinea pigs induced by ovalbumin(OVA). This study aims to determine whether the combined blockade of IL-1β and TNF-α can more effectively inhibit allergic inflammation in allergic rhinitis(AR) guinea pigs induced by OVA. Healthy guinea pigs treated with saline were used as the healthy control. The AR guinea pigs induced by OVA were randomly divided into (1) the AR model group containing negative control animals treated with intranasal saline; (2) the 0.1% non-specific IgY treatment group treated with non-specific IgY; (3) the 0.1% anti-TNF-α IgY treatment group treated with 0.1% anti-TNF-α IgY; (4) the 0.1% anti-IL-1β IgY treatment group treated with 0.1% anti-IL-1β IgY; (5) the 0.1% combined anti-IL-1β IgY and anti-TNF-α IgY treatment group treated with 0.1% combined anti-IL-1β IgY and anti-TNF-α IgY; and (6) the fluticasone propionate treatment group treated with fluticasone propionate. Cytokines were measured using an enzyme-linked immunosorbent assay. The results showed that IL-1β, IL-5, IL-9, IL-13, IL-18, IL-22, IL-33, TNF-α, TGF-β1 and OVA-specific IgE levels in the peripheral blood (PB) and nasal lavage fluid (NLF) significantly decreased at 2h, 4h or 8h in the 0.1% combined anti-IL-1β IgY and anti-TNF-α IgY treatment group compared to the AR model group and the 0.1% non-specific IgY treatment group (P<0.05). The data suggest that blockade of IL-1β and TNF-α by intranasal instillation of combined anti-IL-1β IgY and anti-TNF-α IgY could be a potential alternative strategy for preventing and treating allergic rhinitis. Copyright © 2014. Published by Elsevier B.V.

  14. Instrumentation

    International Nuclear Information System (INIS)

    Muehllehner, G.; Colsher, J.G.

    1982-01-01

    This chapter reviews the parameters which are important to positron-imaging instruments. It summarizes the options which various groups have explored in designing tomographs and the methods which have been developed to overcome some of the limitations inherent in the technique as well as in present instruments. The chapter is not presented as a defense of positron imaging versus single-photon or other imaging modality, neither does it contain a description of various existing instruments, but rather stresses their common properties and problems. Design parameters which are considered are resolution, sampling requirements, sensitivity, methods of eliminating scattered radiation, random coincidences and attenuation. The implementation of these parameters is considered, with special reference to sampling, choice of detector material, detector ring diameter and shielding and variations in point spread function. Quantitation problems discussed are normalization, and attenuation and random corrections. Present developments mentioned are noise reduction through time-of-flight-assisted tomography and signal to noise improvements through high intrinsic resolution. Extensive bibliography. (U.K.)

  15. The complementarity-determining region sequences in IgY antivenom hypervariable regions

    Directory of Open Access Journals (Sweden)

    David Gitirana da Rocha

    2017-08-01

    Full Text Available The data presented in this article are related to the research article entitled "Development of IgY antibodies against anti-snake toxins endowed with highly lethal neutralizing activity" (da Rocha et al., 2017 [1]. Complementarity-determining region (CDR sequences are variable antibody (Ab sequences that respond with specificity, duration and strength to identify and bind to antigen (Ag epitopes. B lymphocytes isolated from hens immunized with Bitis arietans (Ba and anti-Crotalus durissus terrificus (Cdt venoms and expressing high specificity, affinity and toxicity neutralizing antibody titers were used as DNA sources. The VLF1, CDR1, CDR2, VLR1 and CDR3 sequences were validated by BLASTp, and values corresponding to IgY VL and VH anti-Ba or anti-Cdt venoms were identified, registered [Gallus gallus IgY Fv Light chain (GU815099/Gallus gallus IgY Fv Heavy chain (GU815098] and used for molecular modeling of IgY scFv anti-Ba. The resulting CDR1, CDR2 and CDR3 sequences were combined to construct the three - dimensional structure of the Ab paratope.

  16. Geomagnetism and Aeronomy activities in Italy during IGY, 1957/58

    Directory of Open Access Journals (Sweden)

    Lucilla Alfonsi

    2009-06-01

    Full Text Available In 2007 several events were organized to celebrate the fiftieth anniversary of the International Geophysical Year
    (IGY, 1957-1958. The celebrations will last until 2009 and are taking place within different contexts: the International
    Polar Year (IPY, the International Heliophysical Year (IHY, the electronic Geophysical Year (eGY
    and the International Year of Planet Earth (IYPE.
    IGY offered a very appropriate and timely occasion to undertake a series of coordinated observations of various
    geophysical phenomena all over the globe. Italy took part in the broad international effort stimulated by IGY. In
    fact, Italy participated in observations and studies in many of the proposed scientific areas, in particular Geomagnetism
    and Aeronomy. The Istituto Nazionale di Geofisica (ING started the installation of observatories,
    and updated and ensured continuous recording of geophysical observations. Geomagnetism, ionospheric
    physics, seismology, and other geophysical disciplines, were advanced. Although much of the work was undertaken
    in Italy, some attention was also devoted to other areas of the world, in particular Antarctica, where Italy
    participated in seismological observations. This paper gives a summary of the Geomagnetism and Ionospheric
    Physics activities within IGY. Furthermore, we highlight the importance of this historical event and its outcomes
    for the improvement of geophysical observations and the post-IGY growth of scientific investigations in Italy.

  17. 3D-HST: A Wide-field Grism Spectroscopic Survey with the Hubble Space Telescope

    Science.gov (United States)

    Brammer, Gabriel B.; van Dokkum, Pieter G.; Franx, Marijn; Fumagalli, Mattia; Patel, Shannon; Rix, Hans-Walter; Skelton, Rosalind E.; Kriek, Mariska; Nelson, Erica; Schmidt, Kasper B.; Bezanson, Rachel; da Cunha, Elisabete; Erb, Dawn K.; Fan, Xiaohui; Förster Schreiber, Natascha; Illingworth, Garth D.; Labbé, Ivo; Leja, Joel; Lundgren, Britt; Magee, Dan; Marchesini, Danilo; McCarthy, Patrick; Momcheva, Ivelina; Muzzin, Adam; Quadri, Ryan; Steidel, Charles C.; Tal, Tomer; Wake, David; Whitaker, Katherine E.; Williams, Anna

    2012-06-01

    We present 3D-HST, a near-infrared spectroscopic Treasury program with the Hubble Space Telescope for studying the physical processes that shape galaxies in the distant universe. 3D-HST provides rest-frame optical spectra for a sample of ~7000 galaxies at 1 < z < 3.5, the epoch when ~60% of all star formation took place, the number density of quasars peaked, the first galaxies stopped forming stars, and the structural regularity that we see in galaxies today must have emerged. 3D-HST will cover three quarters (625 arcmin2) of the CANDELS Treasury survey area with two orbits of primary WFC3/G141 grism coverage and two to four orbits with the ACS/G800L grism in parallel. In the IR, these exposure times yield a continuum signal-to-noise ratio of ~5 per resolution element at H 140 ~ 23.1 and a 5σ emission-line sensitivity of ~5 × 10-17 erg s-1 cm-2 for typical objects, improving by a factor of ~2 for compact sources in images with low sky background levels. The WFC3/G141 spectra provide continuous wavelength coverage from 1.1 to 1.6 μm at a spatial resolution of ~0farcs13, which, combined with their depth, makes them a unique resource for studying galaxy evolution. We present an overview of the preliminary reduction and analysis of the grism observations, including emission-line and redshift measurements from combined fits to the extracted grism spectra and photometry from ancillary multi-wavelength catalogs. The present analysis yields redshift estimates with a precision of σ(z) = 0.0034(1 + z), or σ(v) ≈ 1000 km s-1. We illustrate how the generalized nature of the survey yields near-infrared spectra of remarkable quality for many different types of objects, including a quasar at z = 4.7, quiescent galaxies at z ~ 2, and the most distant T-type brown dwarf star known. The combination of the CANDELS and 3D-HST surveys will provide the definitive imaging and spectroscopic data set for studies of the 1 < z < 3.5 universe until the launch of the James Webb Space

  18. 3D-HST: A WIDE-FIELD GRISM SPECTROSCOPIC SURVEY WITH THE HUBBLE SPACE TELESCOPE

    International Nuclear Information System (INIS)

    Brammer, Gabriel B.; Van Dokkum, Pieter G.; Skelton, Rosalind E.; Nelson, Erica; Bezanson, Rachel; Leja, Joel; Lundgren, Britt; Franx, Marijn; Fumagalli, Mattia; Patel, Shannon; Labbé, Ivo; Rix, Hans-Walter; Schmidt, Kasper B.; Da Cunha, Elisabete; Kriek, Mariska; Erb, Dawn K.; Fan, Xiaohui; Förster Schreiber, Natascha; Illingworth, Garth D.; Magee, Dan

    2012-01-01

    We present 3D-HST, a near-infrared spectroscopic Treasury program with the Hubble Space Telescope for studying the physical processes that shape galaxies in the distant universe. 3D-HST provides rest-frame optical spectra for a sample of ∼7000 galaxies at 1 2 ) of the CANDELS Treasury survey area with two orbits of primary WFC3/G141 grism coverage and two to four orbits with the ACS/G800L grism in parallel. In the IR, these exposure times yield a continuum signal-to-noise ratio of ∼5 per resolution element at H 140 ∼ 23.1 and a 5σ emission-line sensitivity of ∼5 × 10 –17 erg s –1 cm –2 for typical objects, improving by a factor of ∼2 for compact sources in images with low sky background levels. The WFC3/G141 spectra provide continuous wavelength coverage from 1.1 to 1.6 μm at a spatial resolution of ∼0.''13, which, combined with their depth, makes them a unique resource for studying galaxy evolution. We present an overview of the preliminary reduction and analysis of the grism observations, including emission-line and redshift measurements from combined fits to the extracted grism spectra and photometry from ancillary multi-wavelength catalogs. The present analysis yields redshift estimates with a precision of σ(z) = 0.0034(1 + z), or σ(v) ≈ 1000 km s –1 . We illustrate how the generalized nature of the survey yields near-infrared spectra of remarkable quality for many different types of objects, including a quasar at z = 4.7, quiescent galaxies at z ∼ 2, and the most distant T-type brown dwarf star known. The combination of the CANDELS and 3D-HST surveys will provide the definitive imaging and spectroscopic data set for studies of the 1 < z < 3.5 universe until the launch of the James Webb Space Telescope.

  19. IGI (the Italian Grid initiative) and its impact on the Astrophysics community

    Science.gov (United States)

    Pasian, F.; Vuerli, C.; Taffoni, G.

    IGI - the Association for the Italian Grid Infrastructure - has been established as a consortium of 14 different national institutions to provide long term sustainability to the Italian Grid. Its formal predecessor, the Grid.it project, has come to a close in 2006; to extend the benefits of this project, IGI has taken over and acts as the national coordinator for the different sectors of the Italian e-Infrastructure present in EGEE. IGI plans to support activities in a vast range of scientificdisciplines - e.g. Physics, Astrophysics, Biology, Health, Chemistry, Geophysics, Economy, Finance - and any possible extensions to other sectors such as Civil Protection, e-Learning, dissemination in Universities and secondary schools. Among these, the Astrophysics community is active as a user, by porting applications of various kinds, but also as a resource provider in terms of computing power and storage, and as middleware developer.

  20. Produksi IgY Antivirus Avian Influenza H5N1 dan Prospek Pemanfaatannya dalam Pengebalan Pasif

    Directory of Open Access Journals (Sweden)

    I Wayan Teguh Wibawan

    2009-09-01

    Full Text Available Immunoglobulin Y (IgY in yolk has been shown in several studies to prevent both bacterial and viralinfections. This research was conducted to find evidence that IgY specific against avian influenza virus(AIV of H5N1 subtype can be produced in a large quantity in egg yolk. Laying hens were vaccinated withAI killed-vaccine (IPB-Shigeta. The IgY was purified using affinity chromatograpy technique, and anti-H5activity was measured using a standard haemaglutination inhibition (HI and agar gel immunodifusion.The concentration of IgY was calculated, and the protein pattern was detected using polyacrilamid gel(AGID electrophoresis (PAGE. Anti H5 antibody as high as 27 – 29 HI units was detected and produce aspecific line of precipitation in AGID. The concentration of IgY was 7.89 mg/ml. Purified specific IgY consistof 6 main protein bands with molecular weights ranging from 35 to 225 kD. These proteins were sensitiveto heat treatment (75oC for 30 minutes, to acid condition (pH2 as well as the pepsin and trypsin. Theseresults indicated the possibility of using specific IgY for passive immunisation to prevent AIV infection oras immunotherapeutic applications for AI treatment in humans.

  1. The potency of chicken egg yolk immunoglobulin (IgY specific as immunotherapy to Mycobacterium tuberculosis infection

    Directory of Open Access Journals (Sweden)

    Sri Agus Sudjarwo

    2017-01-01

    Full Text Available The aim of this study was to characterize of chicken egg yolk immunoglobulins (IgYs specific as immunotherapy to Mycobacterium tuberculosis complex (MTBC infection. Lohmann laying hens were immunized intramuscularly with antigenic of MTBC. Egg yolk was separated from egg white, and IgY antibody was then purified by multiple polyethylene glycols 6000 extraction and ammonium sulfate purification steps. The IgY anti-MTBC concentration in egg yolk increased at 2 weeks and it reached a maximum at 4 weeks after immunization. After 6 weeks, the levels of IgY anti-MTBC decreased gradually. The antibody of MTBC was detected and produces a specific line of precipitation in agar gel precipitation test beginning the week 2 after the first immunization. Analysis of results obtained with ELISA showed a significant increase in the MTBC specific antibodies after 2 weeks and reached a plateau at 4 weeks from the booster immunization. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis revealed the IgY preparation to be pure and dissociated into protein bands with molecular weights of 112, 78, 69, 49, and 28 kDa and Western blot analysis shown the presence of anti-MTBC IgY in egg yolks, with molecular weights of approximately 78 kDa. These results suggested that egg yolk could be a practical strategy in large-scale production of specific anti-MTBC IgY for immunotherapy of TBC.

  2. The ability of IgY to recognize surface proteins of Streptococcus mutans

    Directory of Open Access Journals (Sweden)

    Basri A. Gani

    2009-12-01

    Full Text Available Background: Streptococcus mutans are gram positive bacteria classified into viridians group, and have a role in pathogenesis of dental caries. It’s adhesion to the tooth surface is mediated by cell surface proteins, which interact with specific receptor located in tooth pellicle. Glucan binding protein, Glukosyltransferase, and antigen I/II are basic proteins of S. mutans, which have a role in initiating the interaction. A previous study showed that chicken’s IgY can interfere the interaction. Purpose: The objective of this study was to assess the ability of IgY in recognizing the surface molecule of Streptococcus mutans expressed by various serotypes (c, d, e, f and a strain derived from IPB, Bogor. Method: Western blot was used as a method to determine such capability. Result: The result showed that IgY has a potency to recognize antigen I/II, but not the other proteins on the cell surface of all bacteria tested. Conclusion: The ability of IgY to bind the surface protein, antigen I/II, indicates that this avian antibody could be used as a candidate for anti-adhesion in preventing dental caries.

  3. Evidence of IgY subclass diversification in snakes: evolutionary implications.

    Science.gov (United States)

    Wang, Tao; Sun, Yi; Shao, Wenwei; Cheng, Gang; Li, Lingxiao; Cao, Zubing; Yang, Zhi; Zou, Huiying; Zhang, Wei; Han, Binyue; Hu, Yang; Ren, Liming; Hu, Xiaoxiang; Guo, Ying; Fei, Jing; Hammarström, Lennart; Li, Ning; Zhao, Yaofeng

    2012-10-01

    Mammalian IgG and IgE are thought to have evolved from IgY of nonmammalian tetrapods; however, no diversification of IgY subclasses has been reported in reptiles or birds, which are phylogenetically close to mammals. To our knowledge, we report the first evidence of the presence of multiple IgY-encoding (υ) genes in snakes. Two υ genes were identified in the snake Elaphe taeniura, and three υ genes were identified in the Burmese python (Python molurus bivittatus). Although four of the υ genes displayed a conventional four-H chain C region exon structure, one of the υ genes in the Burmese python lacked the H chain C region 2 exon, thus exhibiting a structure similar to that of the mammalian γ genes. We developed mouse mAbs specific for the IgY1 and IgY2 of E. taeniura and showed that both were expressed in serum; each had two isoforms: one full-length and one truncated at the C terminus. The truncation was not caused by alternative splicing or transcriptional termination. We also identified the μ and δ genes, but no α gene, in both snakes. This study provides valuable clues for our understanding of Ig gene evolution in tetrapods.

  4. IgY Technology: Extraction of Chicken Antibodies from Egg Yolk by Polyethylene Glycol (PEG) Precipitation

    Science.gov (United States)

    Pauly, Diana; Chacana, Pablo A.; Calzado, Esteban G.; Brembs, Björn; Schade, Rüdiger

    2011-01-01

    Hens can be immunized by means of i.m. vaccination (Musculus pectoralis, left and right, injection volume 0.5-1.0 ml) or by means of Gene-Gun plasmid-immunization. Dependent on the immunogenicity of the antigen, high antibody-titres (up to 1:100,000 - 1:1,000,000) can be achieved after only one or 3 - 4 boost immunizations. Normally, a hen lays eggs continuously for about 72 weeks, thereafter the laying capacity decreases. This protocol describes the extraction of total IgY from egg yolk by means of a precipitation procedure (PEG. Polson et al. 1980). The method involves two important steps. The first one is the removal of lipids and the second is the precipitation of total IgY from the supernatant of step one. After dialysis against a buffer (normally PBS) the IgY-extract can be stored at -20°C for more than a year. The purity of the extract is around 80 %, the total IgY per egg varies from 40-80 mg, dependent on the age of the laying hen. The total IgY content increases with the age of the hen from around 40 mg/egg up to 80 mg/egg (concerning PEG precipitation). The laying capacity of a hen per year is around 325 eggs. That means a total potential harvest of 20 g total IgY/year based on a mean IgY content of 60 mg total IgY/egg (see Table 1). PMID:21559009

  5. [Clinical study on the effect of anti-gingivitis IgY toothpaste in control of gingivitis and dental plaque].

    Science.gov (United States)

    Zhang, Wei; Feng, Xi-Ping; Tao, Dan-Ying; Chen, Jian-Fen

    2016-08-01

    To observe the effect of anti-gingivitis IgY toothpaste in control of gingivitis and plaque. The study was a double-blind, randomized, parallel-controlled clinical trail with a total of 100 subjects who were divided into two groups, experimental group and control group. The subjects in experimental group used anti-gingivitis IgY toothpaste to brush twice daily for 3 minutes, and the subjects in control group used none anti-gingivitis IgY toothpaste. The examiner recorded GI, PI and BOP index of all subjects at the baseline, 6-weeks and 12-weeks. SPSS21.0 software package was used for statistical analysis. Twelve weeks later, there were significant differences in GI and BOP between the two groups. Yet no significant difference was found in PI. Anti-gingivitis IgY toothpaste is effective in control of gingivitis.

  6. Aktivitas Biologis Imunoglobulin Yolk Anti Parvovirus Setelah Perlakuan Suhu (BIOLOGY ACTIVITIES OF IgY PARVOVIRUS AFTER HEAT TREATMENT

    Directory of Open Access Journals (Sweden)

    I Gusti Ayu Agung Suartini

    2016-02-01

    Full Text Available This study aims to determine the effect of temperature on the biological activity of various crude and precipitate specific Immunoglobulin (IgY Canine parvovirus (CPV. Hiperimun serum conducted on Isa Brown chickens injected with antigen CPV. Crude yolk Ig preparations derived from chicken serum without purification while the yolk Ig preparations precipitates obtained by the chicken serum was precipitated with ammonium sulfate and dialyzed. Both types of Ig yolk given treatment temperature 50ºC, 60ºC, 70ºC, and 80ºC for 15 minutes. To test Gel Precipitation Test (AGPT is performed to determine whether there is a specific IgY CPV in the serum of chickens. Biological activity of both types of Ig detected with Barriers Haemagglutination test (HI. The design used in this study is completely randomized design factorial. The results of this study indicate that the temperature was highly significant on the activities of IgY crude and precipitates. Activities IgY crude and precipitate down to the treatment temperature of 50ºC, 60ºC, 70ºC, and 80ºC. Geometric Mean Titer crude IgY respectively - were 26.67, 26, 25.33, and <2º Unit HI while IgY precipitates are respectively 26.33, 25.67, 24, and <2º Unit HI. Based on the results of this study concluded that the biological activity of crude IgY better than IgY precipitates after treatment of a wide range of temperatures.

  7. Protective effect of an egg yolk-derived immunoglobulin (IgY) against Prevotella intermedia-mediated gingivitis.

    Science.gov (United States)

    Hou, Y-Y; Zhen, Y-H; Wang, D; Zhu, J; Sun, D-X; Liu, X-T; Wang, H-X; Liu, Y; Long, Y-Y; Shu, X-H

    2014-04-01

    To investigate the effects of an egg yolk-derived immunoglobulin (IgY) specific to Prevotella intermedia in vitro and in vivo. An IgY specific to P. intermedia was produced by immunizing hens with formaldehyde-inactivated P. intermedia and showed high titres when subjected to an ELISA. The obtained IgY inhibited the growth of P. intermedia in a dose-dependent manner at concentrations from 1 to 20 mg ml(-1) in Center for Disease Control and Prevention liquid medium. Forty rats were challenged with P. intermedia on gingivae and then randomly divided into four groups, which were syringed respectively with phosphate-buffered saline, 1 mg ml(-1) of tinidazole, 20 mg ml(-1) of nonspecific IgY and 20 mg ml(-1) of the IgY specific to P. intermedia at a dosage of 300 μl per day. Gingival index (GI), plaque index (PI), bleeding on probing (BOP), counts of white blood cell (WBC) and histopathological slide of the gums were measured after treatment for 15 days. The gingivitis rats treated with the IgY specific to P. intermedia showed significantly decreased GI, PI, BOP and WBC (P intermedia-mediated gingivitis. A new immunoglobulin specific to P. intermedia was developed from egg yolk. This specific IgY can dose-dependently inhibit the growth of P. intermedia and protect rats from gingivitis induced by P. intermedia. The new IgY has potential for the treatment of P. intermedia-mediated gingivitis. © 2013 The Society for Applied Microbiology.

  8. Chicken egg yolk antibodies (IgY) as non-antibiotic production enhancers for use in swine production: a review

    OpenAIRE

    Li, Xiaoyu; Wang, Lili; Zhen, Yuhong; Li, Shuying; Xu, Yongping

    2015-01-01

    In recent years, the use of in-feed antibiotics for growth and disease prevention in livestock production has been under severe scrutiny. The use and misuse of in-feed antibiotics has led to problems with drug residues in animal products and increased bacterial resistance. Chicken egg yolk antibodies (IgY) have attracted considerable attention as an alternative to antibiotics to maintain swine health and performance. Oral administration of IgY possesses many advantages over mammalian IgG such...

  9. Protective effects of chicken egg yolk antibody (IgY) against experimental Vibrio splendidus infection in the sea cucumber (Apostichopus japonicus).

    Science.gov (United States)

    Li, Xiaoyu; Jing, Kailin; Wang, Xitao; Li, Yuan; Zhang, Meixia; Li, Zhen; Xu, Le; Wang, Lili; Xu, Yongping

    2016-01-01

    Vibrio splendidus is one of the most harmful pathogens associated with skin ulceration syndrome in the sea cucumber (Apostichopus japonicus) due to its high virulence and frequency of appearance. The objective of this study was to determine the effectiveness of chicken egg yolk antibody (IgY) against V. splendidus infection in the sea cucumber. Whole V. splendidus cells were used as an immunogen to immunize 20 White Leghorn hens (25 weeks old). IgY was produced from egg yolks obtained from these immunized hens using water dilution, two-step salt precipitation and ultrafiltration. The purity of the IgY produced was approximately 83%. Enzyme-linked Immunosorbent Assay indicated a high specificity for IgY with a maximum antibody titer of 320,000. The growth of V. splendidus in liquid medium was significantly inhibited by IgY in a dose-dependent manner at concentrations ranging from 1 to 10 mg/mL. The protective effects of IgY were evaluated in sea cucumber by intraperitoneally injecting anti-V. splendidus IgY antibodies (10 mg/mL) or immersing the sea cucumber in aqueous IgY (1 g/L) after an intraperitoneal injection of V. splendidus. Intraperitoneal injection resulted in an 80% survival while immersion resulted in a 75% survival during the 11-day experimental period. The survival rates were significantly higher than the positive control and the non-specific IgY group (P sea cucumber treated with specific IgY than those treated with non-specific IgY. The phagocytosis of coelomocytes for V. splendidus in the presence of specific IgY was significantly (P sea cucumbers against V. splendidus infection. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Effect of Chicken Egg Yolk Antibodies (IgY) against Diarrhea in Domesticated Animals: A Systematic Review and Meta-Analysis

    OpenAIRE

    Diraviyam, Thirumalai; Zhao, Bin; Wang, Yuan; Schade, Ruediger; Michael, Antonysamy; Zhang, Xiaoying

    2014-01-01

    Background IgY antibodies are serum immunoglobulin in birds, reptiles and amphibians, and are transferred from serum to egg yolk to confer passive immunity to their embryos and offspring. Currently, the oral passive immunization using chicken IgY has been focused as an alternative to antibiotics for the treatment and control of diarrhea in animals and humans. This systematic review was focused to determine the effect of IgY in controlling and preventing diarrhea in domesticated animals includ...

  11. Research on the Earth's Interior Conducted by Russia after IGY: The Geotraverse Project and "Intermargins"

    Directory of Open Access Journals (Sweden)

    A G Rodnikov

    2009-04-01

    Full Text Available Fifty years have passed since the International Geophysical Year (IGY of 1957.58, one of the most important and noble initiatives in the history of science and in the history of humanity in general. IGY became the model for subsequent international scientific initiatives in various fields of solid Earth research, including the Upper Mantle Project (1961.71, the Geodynamic Project (1971.80, the Geotraverse Project (1987.2003, and the "InterMARGINS" Project (2003. The Russian investigations as part of the Geotraverse Project and "InterMARGINS" were aimed at research into the deep structure of the continental margins of East Eurasia, which are characterized by high seismicity, volcanism, and natural cataclysms hazardous to people living there.

  12. IgY antibodies protect against human Rotavirus induced diarrhea in the neonatal gnotobiotic piglet disease model.

    Directory of Open Access Journals (Sweden)

    Celina G Vega

    Full Text Available Group A Rotaviruses are the most common cause of severe, dehydrating diarrhea in children worldwide. The aim of the present work was to evaluate protection against rotavirus (RV diarrhea conferred by the prophylactic administration of specific IgY antibodies (Ab to gnotobiotic piglets experimentally inoculated with virulent Wa G1P[8] human rotavirus (HRV. Chicken egg yolk IgY Ab generated from Wa HRV hyperimmunized hens specifically recognized (ELISA and neutralized Wa HRV in vitro. Supplementation of the RV Ab free cow milk diet with Wa HRV-specific egg yolk IgY Ab at a final ELISA Ab titer of 4096 (virus neutralization -VN- titer = 256 for 9 days conferred full protection against Wa HRV associated diarrhea and significantly reduced virus shedding. This protection was dose-dependent. The oral administration of semi-purified passive IgY Abs from chickens did not affect the isotype profile of the pig Ab secreting cell (ASC responses to Wa HRV infection, but it was associated with significantly fewer numbers of HRV-specific IgA ASC in the duodenum. We further analyzed the pigś immune responses to the passive IgY treatment. The oral administration of IgY Abs induced IgG Ab responses to chicken IgY in serum and local IgA and IgG Ab responses to IgY in the intestinal contents of neonatal piglets in a dose dependent manner. To our knowledge, this is the first study to show that IgY Abs administered orally as a milk supplement passively protect neonatal pigs against an enteric viral pathogen (HRV. Piglets are an animal model with a gastrointestinal physiology and an immune system that closely mimic human infants. This strategy can be scaled-up to inexpensively produce large amounts of polyclonal IgY Abs from egg yolks to be applied as a preventive and therapeutic passive Ab treatment to control RV diarrhea.

  13. VizieR Online Data Catalog: Hubble Legacy Archive ACS grism data (Kuemmel+, 2011)

    Science.gov (United States)

    Kuemmel, M.; Rosati, P.; Fosbury, R.; Haase, J.; Hook, R. N.; Kuntschner, H.; Lombardi, M.; Micol, A.; Nilsson, K. K.; Stoehr, F.; Walsh, J. R.

    2011-09-01

    A public release of slitless spectra, obtained with ACS/WFC and the G800L grism, is presented. Spectra were automatically extracted in a uniform way from 153 archival fields (or "associations") distributed across the two Galactic caps, covering all observations to 2008. The ACS G800L grism provides a wavelength range of 0.55-1.00um, with a dispersion of 40Å/pixel and a resolution of ~80Å for point-like sources. The ACS G800L images and matched direct images were reduced with an automatic pipeline that handles all steps from archive retrieval, alignment and astrometric calibration, direct image combination, catalogue generation, spectral extraction and collection of metadata. The large number of extracted spectra (73,581) demanded automatic methods for quality control and an automated classification algorithm was trained on the visual inspection of several thousand spectra. The final sample of quality controlled spectra includes 47919 datasets (65% of the total number of extracted spectra) for 32149 unique objects, with a median iAB-band magnitude of 23.7, reaching 26.5 AB for the faintest objects. Each released dataset contains science-ready 1D and 2D spectra, as well as multi-band image cutouts of corresponding sources and a useful preview page summarising the direct and slitless data, astrometric and photometric parameters. This release is part of the continuing effort to enhance the content of the Hubble Legacy Archive (HLA) with highly processed data products which significantly facilitate the scientific exploitation of the Hubble data. In order to characterize the slitless spectra, emission-line flux and equivalent width sensitivity of the ACS data were compared with public ground-based spectra in the GOODS-South field. An example list of emission line galaxies with two or more identified lines is also included, covering the redshift range 0.2-4.6. Almost all redshift determinations outside of the GOODS fields are new. The scope of science projects possible

  14. Development and immunochemical evaluation of a novel chicken IgY antibody specific for KLK6

    Directory of Open Access Journals (Sweden)

    Sotiropoulou Georgia

    2012-12-01

    Full Text Available Abstract Background Human kallikrein-related peptidase 6 (KLK6 has been implicated in various types of cancer and in neurodegenerative and demyelinating diseases including multiple sclerosis. Further, anti-KLK6 antibodies attenuated disease manifestations in the mouse model of multiple sclerosis. Availability of specific antibodies against KLK6 is fundamental to the development of improved diagnostic and/or immunotherapeutic applications. Here, we exploited the enhanced immunogenicity of mammalian proteins in avian species to generate a polyclonal antibody against KLK6. Results Chicken were immunized with recombinant KLK6 and antibodies Y (IgYs were purified from egg yolk with a simple procedure and evaluated for KLK6 detection by ELISA and Western blot using recombinant proteins and human cell lysates and supernatants. The anti-KLK6 Y polyclonal exhibited high affinity for KLK6 with a detection limit of 30 fmol. On the other hand, the widely used rabbit polyclonal antibody that was raised against the same recombinant KLK6 had a detection limit of 300 fmol. Moreover, the IgYs did not display any crossreactivity with recombinant KLKs or endogenous KLKs and other cellular proteins. Conclusions Based on its high specificity and sensitivity the developed anti-KLK6 IgY is expected to aid the development of improved diagnostic tools for the detection of KLK6 in biological and clinical samples.

  15. Swift UVOT Grism Observations of Nearby Type Ia Supernovae - I. Observations and Data Reduction

    Science.gov (United States)

    Pan, Y.-C.; Foley, R. J.; Filippenko, A. V.; Kuin, N. P. M.

    2018-05-01

    Ultraviolet (UV) observations of Type Ia supernovae (SNe Ia) are useful tools for understanding progenitor systems and explosion physics. In particular, UV spectra of SNe Ia, which probe the outermost layers, are strongly affected by the progenitor metallicity. In this work, we present 120 Neil Gehrels Swift Observatory UV spectra of 39 nearby SNe Ia. This sample is the largest UV (λ Ia to date, doubling the number of UV spectra and tripling the number of SNe with UV spectra. The sample spans nearly the full range of SN Ia light-curve shapes (Δm15(B) ≈ 0.6-1.8 mag). The fast turnaround of Swift allows us to obtain UV spectra at very early times, with 13 out of 39 SNe having their first spectra observed ≳ 1 week before peak brightness and the earliest epoch being 16.5 days before peak brightness. The slitless design of the Swift UV grism complicates the data reduction, which requires separating SN light from underlying host-galaxy light and occasional overlapping stellar light. We present a new data-reduction procedure to mitigate these issues, producing spectra that are significantly improved over those of standard methods. For a subset of the spectra we have nearly simultaneous Hubble Space Telescope UV spectra; the Swift spectra are consistent with these comparison data.

  16. DISENTANGLING AGN AND STAR FORMATION ACTIVITY AT HIGH REDSHIFT USING HUBBLE SPACE TELESCOPE GRISM SPECTROSCOPY

    Energy Technology Data Exchange (ETDEWEB)

    Bridge, Joanna S.; Zeimann, Gregory R.; Trump, Jonathan R.; Gronwall, Caryl; Ciardullo, Robin; Fox, Derek; Schneider, Donald P., E-mail: jsbridge@psu.edu [Department of Astronomy and Astrophysics, The Pennsylvania State University, University Park, PA 16802 (United States)

    2016-08-01

    Differentiating between active galactic nucleus (AGN) activity and star formation in z ∼ 2 galaxies is difficult because traditional methods, such as line-ratio diagnostics, change with redshift, while multi-wavelength methods (X-ray, radio, IR) are sensitive to only the brightest AGNs. We have developed a new method for spatially resolving emission lines using the Hubble Space Telescope /Wide Field Camera 3 G141 grism spectra and quantifying AGN activity through the spatial gradient of the [O iii]/H β line ratio. Through detailed simulations, we show that our novel line-ratio gradient approach identifies ∼40% more low-mass and obscured AGNs than obtained by classical methods. Based on our simulations, we developed a relationship that maps the stellar mass, star formation rate, and measured [O iii]/H β gradient to the AGN Eddington ratio. We apply our technique to previously studied stacked samples of galaxies at z ∼ 2 and find that our results are consistent with these studies. This gradient method will also be able to inform other areas of galaxy evolution science, such as inside-out quenching and metallicity gradients, and will be widely applicable to future spatially resolved James Webb Space Telescope data.

  17. DISENTANGLING AGN AND STAR FORMATION ACTIVITY AT HIGH REDSHIFT USING HUBBLE SPACE TELESCOPE GRISM SPECTROSCOPY

    International Nuclear Information System (INIS)

    Bridge, Joanna S.; Zeimann, Gregory R.; Trump, Jonathan R.; Gronwall, Caryl; Ciardullo, Robin; Fox, Derek; Schneider, Donald P.

    2016-01-01

    Differentiating between active galactic nucleus (AGN) activity and star formation in z ∼ 2 galaxies is difficult because traditional methods, such as line-ratio diagnostics, change with redshift, while multi-wavelength methods (X-ray, radio, IR) are sensitive to only the brightest AGNs. We have developed a new method for spatially resolving emission lines using the Hubble Space Telescope /Wide Field Camera 3 G141 grism spectra and quantifying AGN activity through the spatial gradient of the [O iii]/H β line ratio. Through detailed simulations, we show that our novel line-ratio gradient approach identifies ∼40% more low-mass and obscured AGNs than obtained by classical methods. Based on our simulations, we developed a relationship that maps the stellar mass, star formation rate, and measured [O iii]/H β gradient to the AGN Eddington ratio. We apply our technique to previously studied stacked samples of galaxies at z ∼ 2 and find that our results are consistent with these studies. This gradient method will also be able to inform other areas of galaxy evolution science, such as inside-out quenching and metallicity gradients, and will be widely applicable to future spatially resolved James Webb Space Telescope data.

  18. Production of IgY by layers injected with Salmonella typhimurium

    Directory of Open Access Journals (Sweden)

    Hee, H. L.

    2017-06-01

    Full Text Available In the present study, production of IgY and performance of layers immunised with Salmonella typhimurium were evaluated. Thirty 23-wk old layers (Lohmann Brown with average body weight of 1.6 � 0.03 kg. were randomly and equally divided into two groups. Both groups were placed in a specific pathogen free room equipped with an exhaust fan. The layers were placed in single battery cages with slightly tilted floor which allowed eggs to roll straight into the collecting tray. Lyophilized, attenuated whole cells of S. typhimurium strain [serotype: Somatic (O, antigen 1, 4, (5, 12, flagella (H N12 phase I: 1; phase II: 1, 2 (Group B] that were emulsified with Freund�s complete adjuvant were used to immunise the layers intramuscularly 3 times at 2-wk interval (treatment group. Layers in the control group were injected with a solution of sterilized phosphate-buffered saline (PBS emulsified with an equal volume of Freund�s complete adjuvant. The experimental period lasted for 14 wks. Specific antibodies were detected by enzyme-linked immunosorbent assay. The results showed that the birds lost weight during the injection period, but the weights slowly increased in the following weeks. However, the weight of layers in the treated group remained lower (P<0.05 when compared to the period before injection. The loss in body weight of layers was the result of reduced feed intake, in particular during the injection weeks. Layers in the control group had a higher egg production, by about 10.1% than layers in the treatment group throughout the experimental period. The egg production for layers in treatment group showed a significant decrease (P<0.05 during the immunization period by 28.8%. The egg production significantly increased (P<0.05 to 71.9% after this period, but the production did not reach the level before immunisation. The weight of eggs of treated layers were significantly lower (P<0.05 than the control layers during the injection weeks. The egg

  19. Moving Beyond IGY: An Electronic Geophysical Year (eGY) Concept

    Science.gov (United States)

    Baker, D. N.; Barton, C. E.; Rodger, A. S.; Thompson, B. J.; Fraser, B.; Papitashvili, V.

    2003-12-01

    During the International Geophysical Year (1957-1958), member countries established many new geophysical observatories pursuing the major IGY objectives - to collect geophysical data as widely as possible and to provide free access to these data for all scientists around the globe. Today, geophysics has attained a rather good understanding within traditional regions, i.e., the atmosphere, ionosphere, magnetosphere, and other such geospheres. At the same time, it has become clear that much of the new and important science is coming from the studies of interfaces and coupling between geospheres. Thus, if geophysical data are made `'transparently'' available to a much wider range of scientists and students than to those who do the observations, then new and exciting discoveries can be expected. An International Association of Geomagnetic and Aeronomy (IAGA) task force, recognizing that a key achievement of the IGY was the establishment of a worldwide system of data centers and physical observatories, proposes that for the 50th anniversary of IGY, the worldwide scientific community should endorse and promote an electronic Geophysical Year (eGY) initiative. The proposed eGY concept would both commemorate the IGY in 2007-2008 and provide a forward impetus to geophysics in 21st century, similar to that provided by the IGY fifty years ago. The IAGA task force strongly advocates: (1) Securing permission and release of existing data; (2) Creating access to information; and (3) Conversion of relevant analog data to digital form. The eGY concept embraces all available and upcoming geophysical data (e.g., atmospheric, ionospheric, geomagnetic, gravity, etc.) through the establishment of a series of virtual geophysical observatories now being `'deployed'' in cyberspace. The eGY concept is modern, global, and timely; it is attractive, pragmatic, and affordable. The eGY is based on the existing and continually developing computing/networking technologies (e.g., XML, Semantic Web

  20. Chicken IgY Fc expressed by Eimeria mitis enhances the immunogenicity of E. mitis.

    Science.gov (United States)

    Qin, Mei; Tang, Xinming; Yin, Guangwen; Liu, Xianyong; Suo, Jingxia; Tao, Geru; Ei-Ashram, Saeed; Li, Yuan; Suo, Xun

    2016-03-21

    Eimeria species are obligate intracellular apicomplexan parasites, causing great economic losses in the poultry industry. Currently wild-and attenuated- type anticoccidial vaccines are used to control coccidiosis. However, their use in fast growing broilers is limited by vaccination side effects caused by medium and/or low immunogenic Eimeria spp. There is, therefore, a need for a vaccine with high immunogenicity for broilers. The avian yolk sac IgY Fc is the avian counterpart of the mammalian IgG Fc, which enhances immunogenicity of Fc-fusion proteins. Here, we developed a stable transgenic Eimeria mitis expressing IgY Fc (Emi.chFc) and investigated whether the avian IgY Fc fragment enhances the immunogenicity of E. mitis. Two-week-old broilers were immunized with either Emi.chFc or wild type Eimeria and challenged with wild type E. mitis to analyze the protective properties of transgenic Emi.chFc. Chickens immunized with Emi.chFc had significantly lower oocyst output, in comparison with PBS, mock control (transgenic E. mitis expressing HA1 from H9N2 avian influenza virus) and wildtype E. mitis immunized groups after challenge, indicating that IgY Fc enhanced the immunogenicity of E. mitis. Our findings suggest that IgY Fc-expressing Eimeria may be a better coccidiosis vaccine, and transgenic Eimeria expressing Fc-fused exogenous antigens may be used as a novel vaccine-delivery vehicle against a wide variety of pathogens.

  1. Leveraging 3D-HST Grism Redshifts to Quantify Photometric Redshift Performance

    Science.gov (United States)

    Bezanson, Rachel; Wake, David A.; Brammer, Gabriel B.; van Dokkum, Pieter G.; Franx, Marijn; Labbé, Ivo; Leja, Joel; Momcheva, Ivelina G.; Nelson, Erica J.; Quadri, Ryan F.; Skelton, Rosalind E.; Weiner, Benjamin J.; Whitaker, Katherine E.

    2016-05-01

    We present a study of photometric redshift accuracy in the 3D-HST photometric catalogs, using 3D-HST grism redshifts to quantify and dissect trends in redshift accuracy for galaxies brighter than JH IR > 24 with an unprecedented and representative high-redshift galaxy sample. We find an average scatter of 0.0197 ± 0.0003(1 + z) in the Skelton et al. photometric redshifts. Photometric redshift accuracy decreases with magnitude and redshift, but does not vary monotonically with color or stellar mass. The 1σ scatter lies between 0.01 and 0.03 (1 + z) for galaxies of all masses and colors below z 2), dusty star-forming galaxies for which the scatter increases to ˜0.1 (1 + z). We find that photometric redshifts depend significantly on galaxy size; the largest galaxies at fixed magnitude have photo-zs with up to ˜30% more scatter and ˜5 times the outlier rate. Although the overall photometric redshift accuracy for quiescent galaxies is better than that for star-forming galaxies, scatter depends more strongly on magnitude and redshift than on galaxy type. We verify these trends using the redshift distributions of close pairs and extend the analysis to fainter objects, where photometric redshift errors further increase to ˜0.046 (1 + z) at {H}F160W=26. We demonstrate that photometric redshift accuracy is strongly filter dependent and quantify the contribution of multiple filter combinations. We evaluate the widths of redshift probability distribution functions and find that error estimates are underestimated by a factor of ˜1.1-1.6, but that uniformly broadening the distribution does not adequately account for fitting outliers. Finally, we suggest possible applications of these data in planning for current and future surveys and simulate photometric redshift performance in the Large Synoptic Survey Telescope, Dark Energy Survey (DES), and combined DES and Vista Hemisphere surveys.

  2. Spatially Resolved HST Grism Spectroscopy of a Lensed Emission Line Galaxy at z ~ 1

    Science.gov (United States)

    Frye, Brenda L.; Hurley, Mairead; Bowen, David V.; Meurer, Gerhardt; Sharon, Keren; Straughn, Amber; Coe, Dan; Broadhurst, Tom; Guhathakurta, Puragra

    2012-07-01

    We take advantage of gravitational lensing amplification by A1689 (z = 0.187) to undertake the first space-based census of emission line galaxies (ELGs) in the field of a massive lensing cluster. Forty-three ELGs are identified to a flux of i 775 = 27.3 via slitless grism spectroscopy. One ELG (at z = 0.7895) is very bright owing to lensing magnification by a factor of ≈4.5. Several Balmer emission lines (ELs) detected from ground-based follow-up spectroscopy signal the onset of a major starburst for this low-mass galaxy (M * ≈ 2 × 109 M ⊙) with a high specific star formation rate (≈20 Gyr-1). From the blue ELs we measure a gas-phase oxygen abundance consistent with solar (12+log(O/H) = 8.8 ± 0.2). We break the continuous line-emitting region of this giant arc into seven ~1 kpc bins (intrinsic size) and measure a variety of metallicity-dependent line ratios. A weak trend of increasing metal fraction is seen toward the dynamical center of the galaxy. Interestingly, the metal line ratios in a region offset from the center by ~1 kpc have a placement on the blue H II region excitation diagram with f ([O III])/f (Hβ) and f ([Ne III])/f (Hβ) that can be fitted by an active galactic nucleus (AGN). This asymmetrical AGN-like behavior is interpreted as a product of shocks in the direction of the galaxy's extended tail, possibly instigated by a recent galaxy interaction. Based, in part, on data obtained with the W. M. Keck Observatory, which is operated as a scientific partnership among the California Institute of Technology, the University of California, and NASA, and was made possible by the generous financial support of the W. M. Keck Foundation.

  3. I.G.Y. Ascaplots annals of the international geophysical year, v.20

    CERN Document Server

    Stoffregen, W

    Annals of the International Geophysical Year, Volume 20, Part II: I.G.Y. Ascaplots is a four-chapter text that provides the data on half-hourly auroral all-sky camera plots from 115 stations for the period 1958-1959. This period cover two winters in the northern hemisphere characterized by high auroral activity. This part also presents the list of stations, as well as the maps of the northern and southern distribution of all-sky cameras, with some modifications and additions to the earlier list. Data from the added Japanese station in the Antarctic are received and are included with the data

  4. IgY Technology: Extraction of Chicken Antibodies from Egg Yolk by Polyethylene Glycol (PEG) Precipitation

    OpenAIRE

    Pauly, Diana; Chacana, Pablo A.; Calzado, Esteban G.; Brembs, Bj?rn; Schade, R?diger

    2011-01-01

    Hens can be immunized by means of i.m. vaccination (Musculus pectoralis, left and right, injection volume 0.5-1.0 ml) or by means of Gene-Gun plasmid-immunization. Dependent on the immunogenicity of the antigen, high antibody-titres (up to 1:100,000 - 1:1,000,000) can be achieved after only one or 3 - 4 boost immunizations. Normally, a hen lays eggs continuously for about 72 weeks, thereafter the laying capacity decreases. This protocol describes the extraction of total IgY from egg yolk b...

  5. Effect of passive immunization by anti-gingipain IgY on periodontal health of dogs

    Directory of Open Access Journals (Sweden)

    Rahman A.K.M. Shofiqur

    2011-09-01

    Full Text Available Anti-gingipain IgY (IgY-GP, known as hyperimmune γ-livetin from egg yolk, inhibits the enzyme activity, growth and adherence of Porphyromonas gingivalis to gingival epithelial cells. Our objective was to evaluate the efficacy of IgY-GP on periodontal health of dogs. IgY-GP was prepared from the egg yolk of hens immunized with the gingipain from Porphyromonas gingivalis ATCC 33277. Two in vivo trial models were conducted on 15 adult dogs with periodontitis by giving IgY-GP-supplemented dog feed for 8 weeks and direct application of the IgY in dental ointment to the periodontal pockets at weekly interval for 4 weeks. Clinical parameters including gingivitis, periodontitis, oral health index, bleeding on probe (BOP, pocket depth (PD, and dental calculus removal pattern for selected premolar teeth were recorded at baseline, 4 and 8 weeks post treatment.IgY-GP showed strong cross-reactivity with gingipain from Porphyromonas gulae and inhibited the enzyme activity in vitro. In the dog trials, IgY-GP resulted in significant improvement of oral health parameters including gingivitis and periodontitis scores, BOP, dental calculus removal. No adverse events during and after antibody applications were noted. Oral immunotherapy by using IgY-GP is a new promising alternative to conventional preventive and therapeutic methods to improve oral health status in dogs.

  6. Effect of chicken egg yolk antibodies (IgY against diarrhea in domesticated animals: a systematic review and meta-analysis.

    Directory of Open Access Journals (Sweden)

    Thirumalai Diraviyam

    Full Text Available BACKGROUND: IgY antibodies are serum immunoglobulin in birds, reptiles and amphibians, and are transferred from serum to egg yolk to confer passive immunity to their embryos and offspring. Currently, the oral passive immunization using chicken IgY has been focused as an alternative to antibiotics for the treatment and control of diarrhea in animals and humans. This systematic review was focused to determine the effect of IgY in controlling and preventing diarrhea in domesticated animals including Piglets, Mice, Poultry and Calves. METHODS AND RESULTS: Previous research reports focused on treatment effect of Chicken IgY against diarrhea were retrieved from different electronic data bases (MEDLINE, EMBASE, SPRINGER-LINK, WILEY, AGRICOLA, MEDWELL Journals, Scientific Publish, Chinese articles from Core periodicals in 2012. A total of 61 studies in 4 different animal classes met the inclusion criteria. Data on study characteristics and outcome measures were extracted. The pooled relative risk (RR of 49 studies of different animals [Piglets--22; Mice--14; Poultry--7 and Calves--6] in meta-analyses revealed that, IgY significantly reduced the risk of diarrhea in treatment group when compare to the placebo. However, the 95% confidence intervals of the majority of studies in animal class piglets and calves embrace RR of one. The same results were obtained in sub group analyses (treatment regiment--prophylactic or therapeutic; pathogen type--bacterial or viral. Perhaps, this inconsistency in the effect of IgY at the individual study level and overall effect measures could be influenced by the methodological heterogeneity. CONCLUSION: The present systematic review (SR and meta-analysis demonstrated the beneficial effect of IgY. This supports the opinion that IgY is useful for prophylaxis and treatment. However, more intensive studies using the gold standard animal experiments with the focus to use IgY alone or in combination with other alternative

  7. Effect of Chicken Egg Yolk Antibodies (IgY) against Diarrhea in Domesticated Animals: A Systematic Review and Meta-Analysis

    Science.gov (United States)

    Diraviyam, Thirumalai; Zhao, Bin; Wang, Yuan; Schade, Ruediger; Michael, Antonysamy; Zhang, Xiaoying

    2014-01-01

    Background IgY antibodies are serum immunoglobulin in birds, reptiles and amphibians, and are transferred from serum to egg yolk to confer passive immunity to their embryos and offspring. Currently, the oral passive immunization using chicken IgY has been focused as an alternative to antibiotics for the treatment and control of diarrhea in animals and humans. This systematic review was focused to determine the effect of IgY in controlling and preventing diarrhea in domesticated animals including Piglets, Mice, Poultry and Calves. Methods and Results Previous research reports focused on treatment effect of Chicken IgY against diarrhea were retrieved from different electronic data bases (MEDLINE, EMBASE, SPRINGER-LINK, WILEY, AGRICOLA, MEDWELL Journals, Scientific Publish, Chinese articles from Core periodicals in 2012). A total of 61 studies in 4 different animal classes met the inclusion criteria. Data on study characteristics and outcome measures were extracted. The pooled relative risk (RR) of 49 studies of different animals [Piglets – 22; Mice – 14; Poultry – 7 and Calves – 6] in meta-analyses revealed that, IgY significantly reduced the risk of diarrhea in treatment group when compare to the placebo. However, the 95% confidence intervals of the majority of studies in animal class piglets and calves embrace RR of one. The same results were obtained in sub group analyses (treatment regiment – prophylactic or therapeutic; pathogen type – bacterial or viral). Perhaps, this inconsistency in the effect of IgY at the individual study level and overall effect measures could be influenced by the methodological heterogeneity. Conclusion The present systematic review (SR) and meta-analysis demonstrated the beneficial effect of IgY. This supports the opinion that IgY is useful for prophylaxis and treatment. However, more intensive studies using the gold standard animal experiments with the focus to use IgY alone or in combination with other alternative

  8. Antiparasitic effects induced by polyclonal IgY antibodies anti-phospholipase A2 from Bothrops pauloensis venom.

    Science.gov (United States)

    Borges, Isabela Pacheco; Silva, Mariana Ferreira; Santiago, Fernanda Maria; de Faria, Lucas Silva; Júnior, Álvaro Ferreira; da Silva, Rafaela José; Costa, Mônica Soares; de Freitas, Vitor; Yoneyama, Kelly Aparecida Geraldo; Ferro, Eloísa Amália Vieira; Lopes, Daiana Silva; Rodrigues, Renata Santos; de Melo Rodrigues, Veridiana

    2018-06-01

    Activities of phospholipases (PLAs) have been linked to pathogenesis in various microorganisms, and implicated in cell invasion and so the interest in these enzymes as potential targets that could contribute to the control of parasite survival and proliferation. Chicken eggs immunized with BnSP-7, a Lys49 phospholipase A 2 (PLA 2 ) homologue from Bothrops pauloensis snake venom, represent an excellent source of polyclonal antibodies with potential inhibitory activity on parasite PLA s. Herein, we report the production, characterization and anti-parasitic effect of IgY antibodies from egg yolks of hens immunized with BnSP-7. Produced antibodies presented increasing avidity and affinity for antigenic toxin epitopes throughout immunization, attaining a plateau after 4weeks. Pooled egg yolks-purified anti-BnSP-7 IgY antibodies were able to specifically recognize different PLA 2 s from Bothrops pauloensis and Bothrops jararacussu venom. Antibodies also neutralized BnSP-7 cytotoxic activity in C2C12 cells. Also, the antibodies recognized targets in Leishmania (Leishmania) amazonensis and Toxoplasma gondii extracts by ELISA and immunofluorescence assays. Anti-BnSP-7 IgY antibodies were cytotoxic to T. gondii tachyzoite and L. (L.) amazonensis promastigotes, and were able to decrease proliferation of both parasites treated before infection. These data suggest that the anti-BnSP-7 IgY is an important tool for discovering new parasite targets and blocking parasitic effects. Copyright © 2018 Elsevier B.V. All rights reserved.

  9. General applicability of chicken egg yolk antibodies: the performance of IgY immunoglobulins raised against the hypoxia-inducible factor 1alpha

    OpenAIRE

    Camenisch, G; Tini, M; Chilov, D; Kvietikova, I; Srinivas, V; Caro, J; Spielmann, P; Wenger, R H; Gassmann, M

    1999-01-01

    Avian embryos and neonates acquire passive immunity by transferring maternal immunoglobulins from serum to egg yolk. Despite being a convenient source of antibodies, egg yolk immunoglobulins (IgY) from immunized hens have so far received scant attention in research. Here we report the generation and rapid isolation of IgY from the egg yolk of hens immunized against the alpha subunit of the human hypoxia-inducible factor 1 (HIF-1alpha). Anti-HIF-1alpha IgY antibodies were affinity purified and...

  10. HUBBLE SPACE TELESCOPE WFC3 GRISM SPECTROSCOPY AND IMAGING OF A GROWING COMPACT GALAXY AT z = 1.9

    International Nuclear Information System (INIS)

    Van Dokkum, Pieter G.; Brammer, Gabriel

    2010-01-01

    We present HST/WFC3 grism near-IR spectroscopy of the brightest galaxy at z > 1.5 in the GOODS-South WFC3 ERS grism pointing. The spectrum is of remarkable quality and shows the redshifted Balmer lines Hβ, Hγ, and Hδ in absorption at z = 1.902 ± 0.002. The absorption lines can be produced by a post-starburst stellar population with a luminosity-weighted age of ∼0.5 Gyr. The mass-to-light ratio inferred from the spectrum implies a stellar mass of (4 ± 1) x 10 11 M sun . We determine the morphology of the galaxy from a deep WFC3 H 160 image. Similar to other massive galaxies at z ∼ 2 the galaxy is compact, with an effective radius of 2.1 ± 0.3 kpc. Although most of the light is in a compact core, the galaxy has two red, smooth spiral arms that appear to be tidally induced. The spatially resolved spectroscopy demonstrates that the center of the galaxy is quiescent whereas the surrounding disk is forming stars, as it shows Hβ in emission. The galaxy interacts with a companion at a projected distance of 18 kpc, which also shows prominent tidal features. The companion is a factor of ∼10 fainter than the primary galaxy and may have a lower metallicity. It is tempting to interpret these observations as evidence for the growth of compact, quiescent high-redshift galaxies through minor mergers, which has been proposed by several recent observational and theoretical studies. Interestingly both objects host luminous active galactic nuclei, which implies that these mergers can be accompanied by significant black hole growth.

  11. Solar Cycle variations of ƒoF2 from IGY to 1990

    Directory of Open Access Journals (Sweden)

    M. K. Goel

    Full Text Available Noontime monthly median values of F2-layer critical frequency foF2 (m for some ionospheric stations representing low- and mid-latitudes are examined for their dependence on solar activity for the years 1957 (IGY to 1990. This is the period for which ionospheric data in digital form is available in two CD-ROMs at the World Data Center, Boulder. It is observed that at mid-latitudes, foF2 (m shows nearly a linear relationship with R12 (the 12-month running average of the Zurich sunspot number, though this relation is nonlinear for low-latitudes. These results indicate some departures from the existing information often used in theoretical and applied areas of space research.Key words. Ionosphere (equatorial ionosphere; mid-latitude ionosphere; modelling and forecasting

  12. Grid: From EGEE to EGI and from INFN-Grid to IGI

    International Nuclear Information System (INIS)

    Giselli, A.; Mazzuccato, M.

    2009-01-01

    In the last fifteen years the approach of the computational Grid has changed the way to use computing resources. Grid computing has raised interest worldwide in academia, industry, and government with fast development cycles. Great efforts, huge funding and resources have been made available through national, regional and international initiatives aiming at providing Grid infrastructures, Grid core technologies, Grid middle ware and Grid applications. The Grid software layers reflect the architecture of the services developed so far by the most important European and international projects. In this paper Grid e-Infrastructure story is given, detailing European, Italian and international projects such as EGEE, INFN-Grid and NAREGI. In addition the sustainability issue in the long-term perspective is described providing plans by European and Italian communities with EGI and IGI.

  13. Eficacia experimental de anticuerpos IgY producidos en huevos, contra el veneno de la serpiente peruana Bothrops atrox Experimental efficacy of IgY antibodies produced in eggs against the venom of the Peruvian snake Bothrops atrox

    Directory of Open Access Journals (Sweden)

    Julio C. Mendoza

    2012-03-01

    Full Text Available Objetivos. Desarrollar un protocolo de inmunización para producir inmunoglobulinas IgY de origen aviar contra el veneno de la serpiente peruana Bothrops atrox y evaluar la capacidad neutralizante. Materiales y métodos. Se inmunizaron seis gallinas de postura de la raza hy line brown con 500 μg/dosis de veneno de B. atrox en un periodo de dos meses. Cada semana, los huevos fueron colectados para el aislamiento de inmunoglobulinas IgY a partir de la yema, usando dos pasos consecutivos con αcido caprνlico y sulfato de amonio. La detecciσn de anticuerpos se realizσ por inmunodifusiσn doble mientras que el tνtulo y reactividad cruzada se determinaron por las técnicas de ELISA y Western blot. El cálculo de DL50 y de la DE50 del antiveneno IgY producido se realizó utilizando el método de Probits. Resultados. La masa de anticuerpos aislados fue de 8,5 ± 1,35 mg de IgY/mL de yema. Asimismo, la DE50 del antiveneno aviar fue calculada en 575 μL de antiveneno/mg de veneno. Adicionalmente, los ensayos de reactividad cruzada mostraron que el veneno de B. atrox comparte mas epνtopes comunes con el veneno de B. brazili (47% que con otros veneno del mismo género, en tanto que los venenos de Lachesis muta (19% y Crotalus durissus (12% mostraron una baja reactividad cruzada. Conclusiones. Se ha obtenido IgY purificada contra el veneno de B. atrox con capacidad neutralizante y se ha demostrado su utilidad como herramienta inmunoanalítica para evaluar la reactividad cruzada con venenos de otras especies.Objectives. To develop an immunization protocol in order to produce avian IgY immunoglobulins against Bothrops atrox Peruvian snake venom and to evaluate its neutralizing capacity. Materials and methods. Six Hy Line Brown hens were immunized each two weeks using 500μg/doses of B. atrox venom in a period of two months. Each week, eggs were collected for IgY isolation from yolk using two consecutive steps with caprilic acid and ammonium sulfate

  14. Production, Characterization and Use of Monoclonal Antibodies Recognizing IgY Epitopes Shared by Chicken, Turkey, Pheasant, Peafowl and Sparrow

    Directory of Open Access Journals (Sweden)

    Ajda Biček

    2004-01-01

    Full Text Available Chicken antibodies are not only a part of immune defense but are more and more popular commercial products in form of chicken polyclonal, monoclonal or recombinant antibodies. We produced and characterized mouse monoclonal antibodies (mAbs that recognize epitopes located on heavy or light chain of chicken immunoglobulin Y (chIgY shared also by some other Phasianidae birds. The use of mAbs 1F5 and 2F10 that recognize heavy chain on chIgY common epitopes was demonstrated on immunoglobulins of turkey, pheasant and peafowl. Chicken IgY light chain specific mAb 3E10 revealed the presence of common epitopes on immunoglobulins of turkey, pheasant and sparrow. Monoclonal antibody clone 1F5/3G2 was used to prepare horseradish peroxidase (HRP conjugate and immunoadsorbent column. Conjugated mAbs were demonstrated to be excellent secondary antibodies for diagnostics of certain infections in different avian species. Since they do not react with mammalian immunoglobulins using our mAbs as secondary antibodies in human serodiagnostics would minimize background staining that appears when using mouse detection system. In dot immunobinding assay (DIBA and immunoblot assay they recognized specific IgY antibodies against Mycoplasma synoviae, Mycoplasma gallisepticum and Newcastle disease virus in sera of infected or vaccinated birds. Immunoadsorption as a method for removal of IgY from samples in which Mycoplasma synoviae specific IgY was predominant immunoglobulin class enabled more exact demonstration of specific IgA and IgM antibodies. Herein we are presenting effective mAbs useful in diagnostics of avian and mammalian infections as well as in final steps of detection and purification of chicken antibodies and their subunits produced in vivo or in vitro as polyclonal, monoclonal or recombinant antibodies.

  15. Growth inhibition of Staphylococcus aureus and escherichia coli strains by neutralizing IgY antibodies from ostrich egg yolk

    Directory of Open Access Journals (Sweden)

    Fernando Luiz Tobias

    2012-06-01

    Full Text Available Ostrich raising around the world have some key factors and farming profit depend largely on information and ability of farmers to rear these animals. Non fertilized eggs from ostriches are discharged in the reproduction season. Staphylococcus aureus and Escherichia coli are microorganisms involved in animal and human diseases. In order to optimize the use of sub products of ostrich raising, non fertilized eggs of four selected birds were utilized for development of polyclonal IgY antibodies. The birds were immunized (200ug/animal with purified recombinant staphylococcal enterotoxin C (recSEC and synthetic recRAP, both derived from S. aureus, and recBFPA and recEspB involved in E. coli pathogenicity, diluted in FCA injected in the braquial muscle. Two subsequent immunization steps with 21 days intervals were repeated in 0,85% saline in FIA. Blood and eggs samples were collected before and after immunization steps. Egg yolk immunoglobulins were purified by precipitation with 19% sodium sulfate and 20% ammonium sulphate methodologies. Purified IgY 50µL aliquots were incubated in 850µL BHI broth containing 50µL inoculums of five strains of S. aureus and five strains of E.coli during four hours at 37ºC. Growth inhibition was evaluated followed by photometry reading (DO550nm. Egg yolk IgY preparation from hiperimmunized birds contained antibodies that inhibited significantly (p<0,05 growth of strains tested. Potential use of ostrich IgY polyclonal antibodies as a diagnostic and therapeutic tool is proposed for diseased animals.

  16. OBTENCIÓN DE ANTICUERPOS POLICLONALES IgY ANTIPARVOVIRUS CANINO A PARTIR DE YEMA DE HUEVO DE GALLINA

    Directory of Open Access Journals (Sweden)

    Pinto, J.

    2005-06-01

    Full Text Available Inmunizando un grupo de diez gallinas de postura raza Lohmann de 16 semanas de edad con parvovirus canino (CPV cepa vacunal, se obtuvieron anticuerpos IgY policlonales contra CPV en yema de huevo.En la extracción de los anticuerpos de la yema se requirieron dos pasos, el primero para la remoción de lípidos y el segundo para la precipitación de proteínas. Para la remoción de lípidos se usó el método PBS:Cloroformo y para la precipitación de los anticuerpos solubles (Inmunoglobulinas-IgY se usó el método de salting-out con sulfato de amonio ((NH42SO4. La evaluación del proceso se efectuó empleando el método comercial estándar “EGGstract IgY Purification System®” de PROMEGA.La metodología empleada permitió la obtención de anticuerpos IgY policlonales contra CPV a partir de yema de huevo de gallina en concentraciones altas por mililitro de yema, con una pureza aceptable y títulos altos; los resultados fueron comparables con el método comercial.

  17. Homogeneous immunoassay for human IgG using oriented hen egg IgY immobilized on gold sol nanoparticles

    International Nuclear Information System (INIS)

    Yeritsyan, H.E.; Gasparyan, V.K.

    2012-01-01

    Homogeneous immunoassays using (red) gold nanoparticles represent an attractive detection scheme because of the option of photometric readout. We have applied oriented immobilization of hen egg immunoglobulin Y (IgY) on gold nanoparticles when developing a homogeneous immunoassay for human IgG. In oriented immobilization, as opposed to random immobilization, the antigen binding capabilities of the antibodies are retained. It is shown that such immunoassay has significantly better sensitivity in comparison with methods based on conventional immobilization of affinity-purified antibodies. It is also shown that hen egg IgY is better suited than rabbit antibodies, because much more antibody can be immobilized on gold nanoparticles without any destabilization, probably because of the more acidic nature of these antibodies. In addition, hen egg IgY can be supplied in higher quantity and can be prepared more easily than IgG from rabbits. Bleeding and slaughtering of animals is not needed. The assay presented here has a wide detection range (30-500 ng. mL -1 ) and a limit of detection as low as 30 ng. mL -1 of human IgG. (author)

  18. Extensive diversification of IgD-, IgY-, and truncated IgY(δFc)-encoding genes in the red-eared turtle (Trachemys scripta elegans).

    Science.gov (United States)

    Li, Lingxiao; Wang, Tao; Sun, Yi; Cheng, Gang; Yang, Hui; Wei, Zhiguo; Wang, Ping; Hu, Xiaoxiang; Ren, Liming; Meng, Qingyong; Zhang, Ran; Guo, Ying; Hammarström, Lennart; Li, Ning; Zhao, Yaofeng

    2012-10-15

    IgY(ΔFc), containing only CH1 and CH2 domains, is expressed in the serum of some birds and reptiles, such as ducks and turtles. The duck IgY(ΔFc) is produced by the same υ gene that expresses the intact IgY form (CH1-4) using different transcriptional termination sites. In this study, we show that intact IgY and IgY(ΔFc) are encoded by distinct genes in the red-eared turtle (Trachemys scripta elegans). At least eight IgY and five IgY(ΔFc) transcripts were found in a single turtle. Together with Southern blotting, our data suggest that multiple genes encoding both IgY forms are present in the turtle genome. Both of the IgY forms were detected in the serum using rabbit polyclonal Abs. In addition, we show that multiple copies of the turtle δ gene are present in the genome and that alternative splicing is extensively involved in the generation of both the secretory and membrane-bound forms of the IgD H chain transcripts. Although a single μ gene was identified, the α gene was not identified in this species.

  19. SWIFT/UVOT GRISM MONITORING OF NGC 5548 IN 2013: AN ATTEMPT AT Mg ii REVERBERATION MAPPING

    Energy Technology Data Exchange (ETDEWEB)

    Cackett, E. M.; Troyer, J. [Department of Physics and Astronomy, Wayne State University, 666 W. Hancock St, Detroit, MI 48201 (United States); Gültekin, K. [Department of Astronomy, University of Michigan, 1085 S. University Ave, Ann Arbor, MI 48109 (United States); Bentz, M. C. [Department of Physics and Astronomy, Georgia State University, Atlanta, GA 30303 (United States); Fausnaugh, M. M.; Peterson, B. M. [Department of Astronomy, The Ohio State University, 140 West 18th Ave, Columbus, OH 43210 (United States); Vestergaard, M., E-mail: ecackett@wayne.edu [Dark Cosmology Centre, The Niels Bohr Institute, Juliane Maries Vej 30, DK-2100 Copenhagen Ø (Denmark)

    2015-09-10

    Reverberation-mapping-based scaling relations are often used to estimate the masses of black holes from single-epoch spectra of active galactic nuclei (AGNs). While the radius–luminosity relation that is the basis of these scaling relations is determined using reverberation mapping of the Hβ line in nearby AGNs, the scaling relations are often extended to use other broad emission lines, such as Mg ii, in order to get black hole masses at higher redshifts when Hβ is redshifted out of the optical waveband. However, there is no radius–luminosity relation determined directly from Mg ii. Here, we present an attempt to perform reverberation mapping using Mg ii in the well-studied nearby Seyfert 1 NGC 5548. We used Swift to obtain UV grism spectra of NGC 5548 once every two days from 2013 April to September. Concurrent photometric UV monitoring with Swift provides a well determined continuum light curve that shows strong variability. The Mg ii emission line, however, is not strongly correlated with the continuum variability, and there is no significant lag between the two. We discuss these results in the context of using Mg ii scaling relations to estimate high-redshift black hole masses.

  20. Quality of electricity service: Evaluation of nuisance index (IGI) of industrial customers; Qualite du service electrique:evaluation de l`indice de gene individuel des clients industriels

    Energy Technology Data Exchange (ETDEWEB)

    Naggar, R. [Hydro-Quebec, Montreal, PQ (Canada)

    1996-08-01

    The effects of power interruption on individual industrial customers by computing an individual nuisance index (IGI) is one of the tools planned by Hydro-Quebec to measure quality of service to its customers. When fully functioning, IGI will represent a combined value of loss of sales, overtime, lost materials and other direct costs, each IGI tailor-made for a particular company. Data for computing the index will be obtained from Hydro-Quebec`s own customer classification database, plus a commercial technical database (DTC) containing data required for the assessment of the nuisance, and a survey carried out by Hydro-Quebec involving some 1600 industrial customers. As of this date, the DTC is not yet available. A statistical analysis of survey responses was substituted to provide default values based on available parameters. Hydro-Quebec is confident that this new approach to evaluating service quality will open new horizons in quality assurance. 3 refs., 5 tabs.

  1. Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils

    DEFF Research Database (Denmark)

    Thomsen, K.; Christophersen, L.; Bjarnsholt, T.

    2015-01-01

    with P. aeruginosa by augmenting the phagocytic competence of PMNs may postpone the deteriorating chronic biofilm infection. Anti-P. aeruginosa IgY antibodies significantly increase the PMN-mediated respiratory burst and subsequent bacterial killing of P. aeruginosa in vitro. The mode of action...... is attributed to IgY-facilitated formation of immobilized bacteria in aggregates, as visualized by fluorescence microscopy and the induction of increased bacterial hydrophobicity. Thus, the present study demonstrates that avian egg yolk immunoglobulins (IgY) targeting P. aeruginosa modify bacterial fitness...

  2. Egg yolk IgY: protection against rotavirus induced diarrhea and modulatory effect on the systemic and mucosal antibody responses in newborn calves.

    Science.gov (United States)

    Vega, C; Bok, M; Chacana, P; Saif, L; Fernandez, F; Parreño, V

    2011-08-15

    Bovine rotavirus (BRV) is an important cause of diarrhea in newborn calves. Local passive immunity is the most efficient protective strategy to control the disease. IgY technology (the use of chicken egg yolk immunoglobulins) is an economic and practical alternative to prevent BRV diarrhea in dairy calves. The aim of this study was to evaluate the protection and immunomodulation induced by the oral administration of egg yolk enriched in BRV specific IgY to experimentally BRV infected calves. All calves in groups Gp 1, 2 and 3 received control colostrum (CC; BRV virus neutralization Ab titer - VN=65,536; ELISA BRV IgG(1)=16,384) prior to gut closure. After gut closure, calves received milk supplemented with 6% BRV-immune egg yolk [(Gp 1) VN=2048; ELISA IgY Ab titer=4096] or non-immune control egg yolk [(Gp 2) VNcontrols (Gp 3 and 4, respectively). Calves were inoculated with 10(5.85)focus forming units (FFU) of virulent BRV IND at 2 days of age. Control calves (Gp 3 and 4) and calves fed control IgY (Gp 2) were infected and developed severe diarrhea. Around 80% calves in Gp 1 (IgY 4096) were infected, but they showed 80% (4/5) protection against BRV diarrhea. Bovine RV-specific IgY Ab were detected in the feces of calves in Gp 1, indicating that avian antibodies (Abs) remained intact after passage through the gastrointestinal tract. At post infection day 21, the duodenum was the major site of BRV specific antibody secreting cells (ASC) in all experimental groups. Mucosal ASC responses of all isotypes were significantly higher in the IgY treated groups, independently of the specificity of the treatment, indicating that egg yolk components modulated the immune response against BRV infection at the mucosal level. These results indicate that supplementing newborn calves' diets for the first 14 days of life with egg yolk enriched in BRV-specific IgY represents a promising strategy to prevent BRV diarrhea. Moreover a strong active ASC immune response is induced in the

  3. 3D-HST GRISM SPECTROSCOPY OF A GRAVITATIONALLY LENSED, LOW-METALLICITY STARBURST GALAXY AT z = 1.847

    International Nuclear Information System (INIS)

    Brammer, Gabriel B.; Sánchez-Janssen, Rubén; Labbé, Ivo; Franx, Marijn; Fumagalli, Mattia; Patel, Shannon; Da Cunha, Elisabete; Rix, Hans-Walter; Schmidt, Kasper B.; Van der Wel, Arjen; Erb, Dawn K.; Lundgren, Britt; Momcheva, Ivelina; Nelson, Erica; Skelton, Rosalind E.; Van Dokkum, Pieter G.; Wake, David A.; Whitaker, Katherine E.; Marchesini, Danilo; Quadri, Ryan

    2012-01-01

    We present Hubble Space Telescope (HST) imaging and spectroscopy of the gravitational lens SL2SJ02176-0513, a cusp arc at z = 1.847. The UV continuum of the lensed galaxy is very blue, which is seemingly at odds with its redder optical colors. The 3D-HST WFC3/G141 near-infrared spectrum of the lens reveals the source of this discrepancy to be extremely strong [O III] λ5007 and Hβ emission lines with rest-frame equivalent widths of 2000 ± 100 and 520 ± 40 Å, respectively. The source has a stellar mass ∼10 8 M ☉ , sSFR ∼ 100 Gyr –1 , and detection of [O III] λ4363 yields a metallicity of 12 + log (O/H) = 7.5 ± 0.2. We identify local blue compact dwarf analogs to SL2SJ02176-0513, which are among the most metal-poor galaxies in the Sloan Digital Sky Survey. The local analogs resemble the lensed galaxy in many ways, including UV/optical spectral energy distribution, spatial morphology, and emission line equivalent widths and ratios. Common to SL2SJ02176-0513 and its local counterparts is an upturn at mid-IR wavelengths likely arising from hot dust heated by starbursts. The emission lines of SL2SJ02176-0513 are spatially resolved owing to the combination of the lens and the high spatial resolution of HST. The lensed galaxy is composed of two clumps with combined size r e ∼300 pc, and we resolve significant differences in UV color and emission line equivalent width between them. Though it has characteristics occasionally attributed to active galactic nuclei, we conclude that SL2SJ02176-0513 is a low-metallicity star-bursting dwarf galaxy. Such galaxies will be found in significant numbers in the full 3D-HST grism survey.

  4. A Search for Lyα Emission from Galaxies AT 6 < z < 8 Using Deep HST Grism Observations: Discovery of a z = 7.5 Galaxy

    Science.gov (United States)

    Larson, Rebecca L.; Finkelstein, Steven; Pirzkal, Nor; Ryan, Russell; Tilvi, Vithal; Malhotra, Sangeeta; Rhoads, James; Finkelstein, Keely; Jung, Intae; Christensen, Lise; Cimatti, Andrea; Ferreras, Ignacio; Grogin, Norman; Koekemoer, Anton; Hathi, Nimish; O'Connell, Robert; Östlin, Göran; Pasquali, Anna; Rothberg, Barry; Windhorst, Rogier; FIGS Team

    2018-01-01

    We have built an automated detection method to find Lyα emission lines in HST grism data from 6 state of the intergalactic medium (IGM) during the epoch of reionization. We use 160 orbits of G102 slitless spectroscopy obtained from HST/WFC3 for the Faint Infrared Grism Survey (FIGS; PI: Malhotra) that were optimized to sample previously-identified high-redshift galaxy candidates. This dataset has already been used to identify one of these candidates, at redshift z = 7.51, which has been observed to have Lyα emission detectable with the HST Grism (Finkelstein et al. 2013; Tilvi et al. 2016). The FIGS data use five separate roll-angles of HST in an effort to mitigate the overall contamination effects of nearby galaxies and we have created a method that accounts for and removes the contamination from surrounding galaxies, while also removing any dispersed continuum light from each individual spectrum (Pirzkal et al. 2017). Using our new automated process we searched for significant (> 3σ) emission lines via two different methods. First, we compared the results for each galaxy across all roll angles and identified significant lines detected in more than one roll angle. Second, we performed a fit to all five roll angles simultaneously, accounting for the total flux of the emission line across all of our spectra. We have examined the spectra for 64 z > 7 candidates in our sample and found one new candidate Lyα emission line at a (> 5σ) level at 1.03µm (FIGS ID: GS2 1406 also named CANDELS ID: z7 PAR2 2909). After comparing this emission line with the broadband photometric colors, we conclude that this line is Lyα at z = 7.542 ± 0.003. This galaxy has the highest Lyα rest-frame equivalent width (EWLyα) yet published at z > 7 (110 ± 14 A).

  5. SOFIA science instruments: commissioning, upgrades and future opportunities

    Science.gov (United States)

    Smith, Erin C.; Miles, John W.; Helton, L. Andrew; Sankrit, Ravi; Andersson, B. G.; Becklin, Eric E.; De Buizer, James M.; Dowell, C. D.; Dunham, Edward W.; Güsten, Rolf; Harper, Doyal A.; Herter, Terry L.; Keller, Luke D.; Klein, Randolf; Krabbe, Alfred; Logsdon, Sarah; Marcum, Pamela M.; McLean, Ian S.; Reach, William T.; Richter, Matthew J.; Roellig, Thomas L.; Sandell, Göran; Savage, Maureen L.; Temi, Pasquale; Vacca, William D.; Vaillancourt, John E.; Van Cleve, Jeffrey E.; Young, Erick T.

    2014-07-01

    The Stratospheric Observatory for Infrared Astronomy (SOFIA) is the world's largest airborne observatory, featuring a 2.5 meter effective aperture telescope housed in the aft section of a Boeing 747SP aircraft. SOFIA's current instrument suite includes: FORCAST (Faint Object InfraRed CAmera for the SOFIA Telescope), a 5-40 μm dual band imager/grism spectrometer developed at Cornell University; HIPO (High-speed Imaging Photometer for Occultations), a 0.3-1.1μm imager built by Lowell Observatory; GREAT (German Receiver for Astronomy at Terahertz Frequencies), a multichannel heterodyne spectrometer from 60-240 μm, developed by a consortium led by the Max Planck Institute for Radio Astronomy; FLITECAM (First Light Infrared Test Experiment CAMera), a 1-5 μm wide-field imager/grism spectrometer developed at UCLA; FIFI-LS (Far-Infrared Field-Imaging Line Spectrometer), a 42-200 μm IFU grating spectrograph completed by University Stuttgart; and EXES (Echelon-Cross-Echelle Spectrograph), a 5-28 μm highresolution spectrometer designed at the University of Texas and being completed by UC Davis and NASA Ames Research Center. HAWC+ (High-resolution Airborne Wideband Camera) is a 50-240 μm imager that was originally developed at the University of Chicago as a first-generation instrument (HAWC), and is being upgraded at JPL to add polarimetry and new detectors developed at Goddard Space Flight Center (GSFC). SOFIA will continually update its instrument suite with new instrumentation, technology demonstration experiments and upgrades to the existing instrument suite. This paper details the current instrument capabilities and status, as well as the plans for future instrumentation.

  6. Production and purification of avian antibodies (IgYs from inclusion bodies of a recombinant protein central in NAD+ metabolism

    Directory of Open Access Journals (Sweden)

    Paula A. Moreno-González

    2013-08-01

    Full Text Available The use of hens for the production of polyclonal antibodies reduces animal intervention and moreover yields a higher quantity of antibodies than other animal models.  The phylogenetic distance between bird and mammal antigens, often leads to more specific avian antibodies than their mammalian counterparts.Since a large amount of antigen is required for avian antibody production, the use of recombinant proteins for this procedure has been growing faster over the last years. Nevertheless, recombinant protein production through heterologous systems frequently prompts the protein to precipitate, forming insoluble aggregates of limited utility (inclusion bodies. A methodology for the production of avian polyclonal antibodies, using recombinant protein from inclusion bodies is presented in this article.In order to produce the antigen, a recombinant Nicotinamide mononucleotide adenylyltransferase from Giardia intestinalis (His-GiNMNAT was expressed in Escherichia coli.  The protein was purified through solubilization from inclusion bodies prior to its renaturalization.  Antibodies were purified from egg yolk of immunized hens by water dilution, followed by ammonium sulfate precipitation and thiophilic affinity chromatography.The purified antibodies were tested against His-GiNMNAT protein in Western blot essays. From one egg yolk, 14.4 mg of highly pure IgY were obtained; this antibody was able to detect 15ng of His-GiNMNAT.  IgY specificity was improved by means of antigen affinity purification, allowing its use for parasite protein recognition.

  7. Anti-Interleukin-1 Beta/Tumor Necrosis Factor-Alpha IgY Antibodies Reduce Pathological Allergic Responses in Guinea Pigs with Allergic Rhinitis

    Directory of Open Access Journals (Sweden)

    Hu Wei-xu

    2016-01-01

    Full Text Available This study aims to determine whether the combined blockade of IL-1β and TNF-α can alleviate the pathological allergic inflammatory reaction in the nasal mucosa and lung tissues in allergic rhinitis (AR guinea pigs. Healthy guinea pigs treated with saline were used as the healthy controls. The AR guinea pigs were randomly divided into (1 the AR model group treated with intranasal saline; (2 the 0.1% nonspecific IgY treatment group; (3 the 0.1% anti-TNF-α IgY treatment group; (4 the 0.1% anti-IL-1β IgY treatment group; (5 the 0.1% combined anti-IL-1β and TNF-α IgY treatment group; and (6 the fluticasone propionate treatment group. The inflammatory cells were evaluated using Wright’s staining. Histopathology was examined using hematoxylin-eosin staining. The results showed that the number of eosinophils was significantly decreased in the peripheral blood, nasal lavage fluid, and bronchoalveolar lavage fluid (P<0.05, and eosinophil, neutrophil, and lymphocyte infiltration and edema were significantly reduced or absent in the nasal mucosa and lung tissues (P<0.05 in the combined 0.1% anti-IL-1β- and TNF-α IgY-treated guinea pigs. The data suggest that topical blockade of IL-1β and TNF-α could reduce pathological allergic inflammation in the nasal mucosa and lung tissues in AR guinea pigs.

  8. Anti-Interleukin-1 Beta/Tumor Necrosis Factor-Alpha IgY Antibodies Reduce Pathological Allergic Responses in Guinea Pigs with Allergic Rhinitis.

    Science.gov (United States)

    Wei-Xu, Hu; Wen-Yun, Zhou; Xi-Ling, Zhu; Zhu, Wen; Li-Hua, Wu; Xiao-Mu, Wu; Hui-Ping, Wei; Wen-Ding, Wang; Dan, He; Qin, Xiang; Guo-Zhu, Hu

    2016-01-01

    This study aims to determine whether the combined blockade of IL-1β and TNF-α can alleviate the pathological allergic inflammatory reaction in the nasal mucosa and lung tissues in allergic rhinitis (AR) guinea pigs. Healthy guinea pigs treated with saline were used as the healthy controls. The AR guinea pigs were randomly divided into (1) the AR model group treated with intranasal saline; (2) the 0.1% nonspecific IgY treatment group; (3) the 0.1% anti-TNF-α IgY treatment group; (4) the 0.1% anti-IL-1β IgY treatment group; (5) the 0.1% combined anti-IL-1β and TNF-α IgY treatment group; and (6) the fluticasone propionate treatment group. The inflammatory cells were evaluated using Wright's staining. Histopathology was examined using hematoxylin-eosin staining. The results showed that the number of eosinophils was significantly decreased in the peripheral blood, nasal lavage fluid, and bronchoalveolar lavage fluid (P guinea pigs. The data suggest that topical blockade of IL-1β and TNF-α could reduce pathological allergic inflammation in the nasal mucosa and lung tissues in AR guinea pigs.

  9. Discovery of a z = 7.452 High Equivalent Width Lyα Emitter from the Hubble Space Telescope  Faint Infrared Grism Survey

    Science.gov (United States)

    Larson, Rebecca L.; Finkelstein, Steven L.; Pirzkal, Norbert; Ryan, Russell; Tilvi, Vithal; Malhotra, Sangeeta; Rhoads, James; Finkelstein, Keely; Jung, Intae; Christensen, Lise; Cimatti, Andrea; Ferreras, Ignacio; Grogin, Norman; Koekemoer, Anton M.; Hathi, Nimish; O’Connell, Robert; Östlin, Göran; Pasquali, Anna; Pharo, John; Rothberg, Barry; Windhorst, Rogier A.; The FIGS Team

    2018-05-01

    We present the results of an unbiased search for Lyα emission from continuum-selected 5.6 data set consists of 160 orbits of G102 slitless grism spectroscopy obtained with the Hubble Space Telescope(HST)/WFC3 as part of the Faint Infrared Grism Survey (FIGS; PI: Malhotra), which obtains deep slitless spectra of all sources in four fields, and was designed to minimize contamination in observations of previously identified high-redshift galaxy candidates. The FIGS data can potentially spectroscopically confirm the redshifts of galaxies, and as Lyα emission is resonantly scattered by neutral gas, FIGS can also constrain the ionization state of the intergalactic medium during the epoch of reionization. These data have sufficient depth to detect Lyα emission in this epoch, as Tilvi et al. have published the FIGS detection of previously known Lyα emission at z = 7.51. The FIGS data use five separate roll angles of HST to mitigate the contamination by nearby galaxies. We created a method that accounts for and removes the contamination from surrounding galaxies and also removes any dispersed continuum light from each individual spectrum. We searched for significant (>4σ) emission lines using two different automated detection methods, free of any visual inspection biases. Applying these methods on photometrically selected high-redshift candidates between 5.6 7 (140.3 ± 19.0 Å).

  10. 3D-HST Grism Spectroscopy of a Gravitationally Lensed, Low-metallicity Starburst Galaxy at z = 1.847

    Science.gov (United States)

    Brammer, Gabriel B.; Sánchez-Janssen, Rubén; Labbé, Ivo; da Cunha, Elisabete; Erb, Dawn K.; Franx, Marijn; Fumagalli, Mattia; Lundgren, Britt; Marchesini, Danilo; Momcheva, Ivelina; Nelson, Erica; Patel, Shannon; Quadri, Ryan; Rix, Hans-Walter; Skelton, Rosalind E.; Schmidt, Kasper B.; van der Wel, Arjen; van Dokkum, Pieter G.; Wake, David A.; Whitaker, Katherine E.

    2012-10-01

    We present Hubble Space Telescope (HST) imaging and spectroscopy of the gravitational lens SL2SJ02176-0513, a cusp arc at z = 1.847. The UV continuum of the lensed galaxy is very blue, which is seemingly at odds with its redder optical colors. The 3D-HST WFC3/G141 near-infrared spectrum of the lens reveals the source of this discrepancy to be extremely strong [O III] λ5007 and Hβ emission lines with rest-frame equivalent widths of 2000 ± 100 and 520 ± 40 Å, respectively. The source has a stellar mass ~108 M ⊙, sSFR ~ 100 Gyr-1, and detection of [O III] λ4363 yields a metallicity of 12 + log (O/H) = 7.5 ± 0.2. We identify local blue compact dwarf analogs to SL2SJ02176-0513, which are among the most metal-poor galaxies in the Sloan Digital Sky Survey. The local analogs resemble the lensed galaxy in many ways, including UV/optical spectral energy distribution, spatial morphology, and emission line equivalent widths and ratios. Common to SL2SJ02176-0513 and its local counterparts is an upturn at mid-IR wavelengths likely arising from hot dust heated by starbursts. The emission lines of SL2SJ02176-0513 are spatially resolved owing to the combination of the lens and the high spatial resolution of HST. The lensed galaxy is composed of two clumps with combined size re ~300 pc, and we resolve significant differences in UV color and emission line equivalent width between them. Though it has characteristics occasionally attributed to active galactic nuclei, we conclude that SL2SJ02176-0513 is a low-metallicity star-bursting dwarf galaxy. Such galaxies will be found in significant numbers in the full 3D-HST grism survey. Based on observations made with the NASA/ESA Hubble Space Telescope, program 12328, obtained at the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS 5-26555.

  11. Dengue virus specific IgY provides protection following lethal dengue virus challenge and is neutralizing in the absence of inducing antibody dependent enhancement.

    Directory of Open Access Journals (Sweden)

    Ashley L Fink

    2017-07-01

    Full Text Available Dengue hemorrhagic fever (DHF and dengue shock syndrome (DSS are severe disease manifestations that can occur following sequential infection with different dengue virus serotypes (DENV1-4. At present, there are no licensed therapies to treat DENV-induced disease. DHF and DSS are thought to be mediated by serotype cross-reactive antibodies that facilitate antibody-dependent enhancement (ADE by binding to viral antigens and then Fcγ receptors (FcγR on target myeloid cells. Using genetically engineered DENV-specific antibodies, it has been shown that the interaction between the Fc portion of serotype cross-reactive antibodies and FcγR is required to induce ADE. Additionally, it was demonstrated that these antibodies were as neutralizing as their non-modified variants, were incapable of inducing ADE, and were therapeutic following a lethal, antibody-enhanced infection. Therefore, we hypothesized that avian IgY, which do not interact with mammalian FcγR, would provide a novel therapy for DENV-induced disease. We demonstrate here that goose-derived anti-DENV2 IgY neutralized DENV2 and did not induce ADE in vitro. Anti-DENV2 IgY was also protective in vivo when administered 24 hours following a lethal DENV2 infection. We were also able to demonstrate via epitope mapping that both full-length and alternatively spliced anti-DENV2 IgY recognized different epitopes, including epitopes that have not been previously identified. These observations provide evidence for the potential therapeutic applications of goose-derived anti-DENV2 IgY.

  12. Dengue virus specific IgY provides protection following lethal dengue virus challenge and is neutralizing in the absence of inducing antibody dependent enhancement.

    Science.gov (United States)

    Fink, Ashley L; Williams, Katherine L; Harris, Eva; Alvine, Travis D; Henderson, Thomas; Schiltz, James; Nilles, Matthew L; Bradley, David S

    2017-07-01

    Dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) are severe disease manifestations that can occur following sequential infection with different dengue virus serotypes (DENV1-4). At present, there are no licensed therapies to treat DENV-induced disease. DHF and DSS are thought to be mediated by serotype cross-reactive antibodies that facilitate antibody-dependent enhancement (ADE) by binding to viral antigens and then Fcγ receptors (FcγR) on target myeloid cells. Using genetically engineered DENV-specific antibodies, it has been shown that the interaction between the Fc portion of serotype cross-reactive antibodies and FcγR is required to induce ADE. Additionally, it was demonstrated that these antibodies were as neutralizing as their non-modified variants, were incapable of inducing ADE, and were therapeutic following a lethal, antibody-enhanced infection. Therefore, we hypothesized that avian IgY, which do not interact with mammalian FcγR, would provide a novel therapy for DENV-induced disease. We demonstrate here that goose-derived anti-DENV2 IgY neutralized DENV2 and did not induce ADE in vitro. Anti-DENV2 IgY was also protective in vivo when administered 24 hours following a lethal DENV2 infection. We were also able to demonstrate via epitope mapping that both full-length and alternatively spliced anti-DENV2 IgY recognized different epitopes, including epitopes that have not been previously identified. These observations provide evidence for the potential therapeutic applications of goose-derived anti-DENV2 IgY.

  13. Chicken Egg Yolk Antibodies (IgY) for Prophylaxis and Treatment of Rotavirus Diarrhea in Human and Animal Neonates: A Concise Review

    Science.gov (United States)

    Thu, Hlaing Myat; Myat, Theingi Win; Win, Mo Mo; Thant, Kyaw Zin; Rahman, Shofiqur; Umeda, Kouji; Nguyen, Sa Van; Icatlo, Faustino C.; Higo-Moriguchi, Kyoko; Taniguchi, Koki; Tsuji, Takao; Oguma, Keiji; Kim, Sang Jong; Bae, Hyun Suk

    2017-01-01

    The rotavirus-induced diarrhea of human and animal neonates is a major public health concern worldwide. Until recently, no effective therapy is available to specifically inactivate the rotavirion particles within the gut. Passive immunotherapy by oral administration of chicken egg yolk antibody (IgY) has emerged of late as a fresh alternative strategy to control infectious diseases of the alimentary tract and has been applied in the treatment of diarrhea due to rotavirus infection. The purpose of this concise review is to evaluate evidence on the properties and performance of anti-rotavirus immunoglobulin Y (IgY) for prevention and treatment of rotavirus diarrhea in human and animal neonates. A survey of relevant anti-rotavirus IgY basic studies and clinical trials among neonatal animals (since 1994-2015) and humans (since 1982-2015) have been reviewed and briefly summarized. Our analysis of a number of rotavirus investigations involving animal and human clinical trials revealed that anti-rotavirus IgY significantly reduced the severity of clinical manifestation of diarrhea among IgY-treated subjects relative to a corresponding control or placebo group. The accumulated information as a whole depicts oral IgY to be a safe and efficacious option for treatment of rotavirus diarrhea in neonates. There is however a clear need for more randomized, placebo controlled and double-blind trials with bigger sample size to further solidify and confirm claims of efficacy and safety in controlling diarrhea caused by rotavirus infection especially among human infants with health issues such as low birth weights or compromised immunity in whom it is most needed. PMID:28316465

  14. PURIFICACIÓN DE IgY CONTRA LA SUBUNIDAD NR3 DEL RECEPTOR NMDA DE CEREBRO DE RATA

    Directory of Open Access Journals (Sweden)

    Gina Méndez C

    2008-04-01

    Full Text Available Objetivo. Obtener anticuerpos tipo IgY contra péptidos sintéticos de las subunidades NR3A y NR3B del receptor NMDA de ratas, para reconocer y seguir la expresión de estas subunidades en extractos de cerebro de rata de diferentes edades. Materiales y métodos. Se diseñaron dos péptidos empleando los sistemas de la base de datos Entrez y el programa ClustalW-PBIL de alineamientos múltiples contra las subunidades NR3A y NR3B del receptor NMDA; una vez sintetizados por el método SSPS-fmoc fueron utilizados para inocular gallinas (Gallus gallus, variedad Hy Line Brown de 16 semanas de edad; al cabo de 57 días postinoculación se purificó IgY específica y se enfrentaron a extractos de cerebro de rata postnatal y adulta. Resultados. Se detectaron las subunidades NR3A y NR3B y se relacionó su expresión con la edad del animal; siendo mayor la expresión de la subunidad NR3A en extracto de cerebro de rata postnatal. No se encontró diferencia marcada en la expresión de la subunidad NR3B en las edades mencionadas. Conclusiones. Esta es la primera investigación que emplea proteína nativa para el reconocimiento de la subunidad NR3 del receptor NMDA, lo cual muestra la especificidad de los anticuerpos generados y contribuye con el entendimiento de las funciones de este receptor y su relación con la regulación de la memoria espacial.

  15. Hen egg yolk antibodies (IgY, production and use for passive immunization against bacterial enteric infections in chicken: a review

    Directory of Open Access Journals (Sweden)

    Chalghoumi R.

    2009-01-01

    Full Text Available Enteric infections caused by Salmonella remain a major public health burden worldwide. Poultry, particularly chickens, are known to be the main reservoir for this zoonotic pathogen. Therefore, the prevention and monitoring of Salmonella infection during the live phase may greatly reduce the contamination of poultry meat during slaughter and processing. With the ban on sub-therapeutic antibiotic usage in Europe and the increasingly strictness of the European legislation on food hygiene, passive immunization by oral administration of pathogen-specific hen egg yolk antibody (IgY may be a useful and attractive alternative. This review offers summarized information about IgY production and the use of these antibodies for passive immunization, particularly in poultry.

  16. A trial with IgY chicken antibodies to eradicate faecal carriage of Klebsiella pneumoniae and Escherichia coli producing extended-spectrum beta-lactamases

    OpenAIRE

    Jonsson, Anna-Karin; Larsson, Anders; Tängdén, Thomas; Melhus, Åsa; Lannergård, Anders

    2015-01-01

    Background: Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae is an emerging therapeutic challenge, especially in the treatment of urinary tract infections. Following an outbreak of CTX-M-15 Klebsiella pneumoniae in Uppsala, Sweden, an orphan drug trial on IgY chicken antibodies was undertaken in an attempt to eradicate faecal carriage of ESBL-producing K. pneumoniae and Escherichia coli.Methods: Hens were immunised with epitopes from freeze-dried, whole-cell bacteria (ESBL...

  17. Chicken Egg Yolk Antibodies (IgY) for Prophylaxis and Treatment of Rotavirus Diarrhea in Human and Animal Neonates: A Concise Review

    OpenAIRE

    Thu, Hlaing Myat; Myat, Theingi Win; Win, Mo Mo; Thant, Kyaw Zin; Rahman, Shofiqur; Umeda, Kouji; Nguyen, Sa Van; Icatlo, Faustino C.; Higo-Moriguchi, Kyoko; Taniguchi, Koki; Tsuji, Takao; Oguma, Keiji; Kim, Sang Jong; Bae, Hyun Suk; Choi, Hyuk Joon

    2017-01-01

    The rotavirus-induced diarrhea of human and animal neonates is a major public health concern worldwide. Until recently, no effective therapy is available to specifically inactivate the rotavirion particles within the gut. Passive immunotherapy by oral administration of chicken egg yolk antibody (IgY) has emerged of late as a fresh alternative strategy to control infectious diseases of the alimentary tract and has been applied in the treatment of diarrhea due to rotavirus infection. The purpos...

  18. Detection of Clonorchis sinensis circulating antigen in sera from Chinese patients by immunomagnetic bead ELISA based on IgY.

    Directory of Open Access Journals (Sweden)

    Ge Nie

    Full Text Available BACKGROUND: Clonorchiasis, caused by Clonorchis sinensis, is widely distributed in Southeast Asia including China. Clonorchiasis is included in control programs of neglected tropical diseases by World Health Organization (WHO because it is one of the major health problems in most endemic areas. Diagnosis of clonorchiasis plays a key role in the control programs. However, so far, there is no satisfactory method for clonorchiasis because of low sensitivity, poor practicality and high false positivity of available diagnostic tools. METHODOLOGY/PRINCIPAL FINDINGS: We developed an immunomagnetic bead enzyme-linked immunosorbent assay (ELISA based on IgY (egg yolk immunoglobulin against cysteine proteinase of C. sinensis for detection of circulating antigen in serum samples of patients infected with C. sinensis. The polyclonal IgY, coated with magnetic beads, was used as a capture antibody and a monoclonal IgG labeled with horseradish peroxidase as a detection antibody in the IgY-based immunomagnetic bead ELISA system (IgY-IMB-ELISA. The results showed that the sensitivity of IgY-IMB-ELISA was 93.3% (14 of 15 in cases of heavy infection (5000 to 9999 eggs per gram feces, i.e, EPG 5000-9999, 86.7% (13 of 15 in cases of moderate infection (EPG 1000-4999 and 75.0% (9 of 12 in cases of light infection (EPG <1000 of clonorchiasis. Together 36 of total 42 (85.7% serum samples of human clonorchiasis gave a positive reaction. There was a significant correlation between ELISA optical density and egg counts (EPG with a correlation coefficient of 0.83 in total 42 patients. There were no positive results in patients with trichinosis (n = 10 or cysticercosis (n = 10. Cross-reactivity was 6.7% (2 of 30 with schistosomiasis japonica and 10.0% (3 of 30 with paragonimiasis, respectively. No positive reaction was found in 20 healthy persons. CONCLUSIONS: Our findings suggest that IgY-IMB-ELISA appears to be a sensitive and specific assay for detection of circulating

  19. Detection of Clonorchis sinensis circulating antigen in sera from Chinese patients by immunomagnetic bead ELISA based on IgY.

    Science.gov (United States)

    Nie, Ge; Wang, Ting; Lu, Shengjun; Liu, Wenqi; Li, Yonglong; Lei, Jiahui

    2014-01-01

    Clonorchiasis, caused by Clonorchis sinensis, is widely distributed in Southeast Asia including China. Clonorchiasis is included in control programs of neglected tropical diseases by World Health Organization (WHO) because it is one of the major health problems in most endemic areas. Diagnosis of clonorchiasis plays a key role in the control programs. However, so far, there is no satisfactory method for clonorchiasis because of low sensitivity, poor practicality and high false positivity of available diagnostic tools. We developed an immunomagnetic bead enzyme-linked immunosorbent assay (ELISA) based on IgY (egg yolk immunoglobulin) against cysteine proteinase of C. sinensis for detection of circulating antigen in serum samples of patients infected with C. sinensis. The polyclonal IgY, coated with magnetic beads, was used as a capture antibody and a monoclonal IgG labeled with horseradish peroxidase as a detection antibody in the IgY-based immunomagnetic bead ELISA system (IgY-IMB-ELISA). The results showed that the sensitivity of IgY-IMB-ELISA was 93.3% (14 of 15) in cases of heavy infection (5000 to 9999 eggs per gram feces, i.e, EPG 5000-9999), 86.7% (13 of 15) in cases of moderate infection (EPG 1000-4999) and 75.0% (9 of 12) in cases of light infection (EPG <1000) of clonorchiasis. Together 36 of total 42 (85.7%) serum samples of human clonorchiasis gave a positive reaction. There was a significant correlation between ELISA optical density and egg counts (EPG) with a correlation coefficient of 0.83 in total 42 patients. There were no positive results in patients with trichinosis (n = 10) or cysticercosis (n = 10). Cross-reactivity was 6.7% (2 of 30) with schistosomiasis japonica and 10.0% (3 of 30) with paragonimiasis, respectively. No positive reaction was found in 20 healthy persons. Our findings suggest that IgY-IMB-ELISA appears to be a sensitive and specific assay for detection of circulating antigen in human clonorchiasis.

  20. Euclid Near Infrared Spectrometer and Photometer instrument concept and first test results obtained for different breadboards models at the end of phase C

    DEFF Research Database (Denmark)

    Maciaszek, Thierry; Ealet, Anne; Jahnke, Knud

    2016-01-01

    program with its launch planned for 2020 (ref [1]). The NISP (Near Infrared Spectrometer and Photometer) is one of the two Euclid instruments and is operating in the near-IR spectral region (900- 2000nm) as a photometer and spectrometer. The instrument is composed of: - a cold (135K) optomechanical...... subsystem consisting of a Silicon carbide structure, an optical assembly (corrector and camera lens), a filter wheel mechanism, a grism wheel mechanism, a calibration unit and a thermal control system - a detection subsystem based on a mosaic of 16 HAWAII2RG cooled to 95K with their front-end readout...

  1. Hypersensitive detection and quantitation of BoNT/A by IgY antibody against substrate linear-peptide.

    Directory of Open Access Journals (Sweden)

    Tao Li

    Full Text Available Botulinum neurotoxin A (BoNT/A, the most acutely poisonous substance to humans known, cleave its SNAP-25 substrate with high specificity. Based on the endopeptidase activity, different methods have been developed to detect BoNT/A, but most lack ideal reproducibility or sensitivity, or suffer from long-term or unwanted interferences. In this study, we developed a simple method to detect and quantitate trace amounts of botulinum neurotoxin A using the IgY antibody against a linear-peptide substrate. The effects of reaction buffer, time, and temperature were analyzed and optimized. When the optimized assay was used to detect BoNT/A, the limit of detection of the assay was 0.01 mouse LD50 (0.04 pg, and the limit of quantitation was 0.12 mouse LD50/ml (0.48 pg. The findings also showed favorable specificity of detecting BoNT/A. When used to detect BoNT/A in milk or human serum, the proposed assay exhibited good quantitative accuracy (88% < recovery < 111%; inter- and intra-assay CVs < 18%. This method of detection took less than 3 h to complete, indicating that it can be a valuable method of detecting BoNT/A in food or clinical diagnosis.

  2. A SOFIA FORCAST Grism Study of the Mineralogy of Dust in the Winds of Proto-planetary Nebulae: RV Tauri Stars and SRd Variables

    Energy Technology Data Exchange (ETDEWEB)

    Arneson, R. A.; Gehrz, R. D.; Woodward, C. E.; Shenoy, D. [Minnesota Institute for Astrophysics, School of Physics and Astronomy, University of Minnesota, 106 Pleasant Street S.E., Minneapolis, MN 55455 (United States); Helton, L. A. [USRA-SOFIA Science Center, NASA Ames Research Center, Moffett Field, CA 94035 (United States); Evans, A. [Astrophysics Group, Lennard Jones Laboratory, Keele University, Keele, Staffordshire ST5 5BG (United Kingdom); Keller, L. D. [Department of Physics and Astronomy, 264 Center for Natural Sciences, Ithaca College, Ithaca, NY 14850 (United States); Hinkle, K. H. [National Optical Astronomy Observatory, P.O. Box 26732, Tucson, AZ 85726 (United States); Jura, M. [Department of Physics and Astronomy, University of California, Los Angeles, CA 90095 (United States); Lebzelter, T. [Institute for Astrophysics (IfA), University of Vienna, Türkenschanzstrasse 17, A-1180 Vienna (Austria); Lisse, C. M. [Solar System Exploration Branch, Space Department, Johns Hopkins University Applied Physics Laboratory, Laurel, MD 20723 (United States); Rushton, M. T. [Astronomical Institute of the Romanian Academy, Str. Cutitul de Argint 5, Bucharest, 040557 (Romania); Mizrachi, J., E-mail: arneson@astro.umn.edu [Biomedical Engineering Department, Stony Brook University, Stony Brook, NY 11794 (United States)

    2017-07-01

    We present a SOFIA FORCAST grism spectroscopic survey to examine the mineralogy of the circumstellar dust in a sample of post-asymptotic giant branch (post-AGB) yellow supergiants that are believed to be the precursors of planetary nebulae. Our mineralogical model of each star indicates the presence of both carbon-rich and oxygen-rich dust species—contrary to simple dredge-up models—with a majority of the dust in the form of amorphous carbon and graphite. The oxygen-rich dust is primarily in the form of amorphous silicates. The spectra do not exhibit any prominent crystalline silicate emission features. For most of the systems, our analysis suggests that the grains are relatively large and have undergone significant processing, supporting the hypothesis that the dust is confined to a Keplerian disk and that we are viewing the heavily processed, central regions of the disk from a nearly face-on orientation. These results help to determine the physical properties of the post-AGB circumstellar environment and to constrain models of post-AGB mass loss and planetary nebula formation.

  3. Production and characterisation of a novel chicken IgY antibody raised against C-terminal peptide from human thymidine kinase 1.

    Science.gov (United States)

    Wu, Chuanjing; Yang, Rongjiang; Zhou, Ji; Bao, Shing; Zou, Li; Zhang, Pinggan; Mao, Yongrong; Wu, Jianping; He, Qimin

    2003-06-01

    Egg yolk is a good source of highly specific antibodies against mammalian antigens because of the phylogenetic distance between birds and mammals. Chicken egg yolk immunoglobulins (IgY) were generated to a synthetic 31-amino acid peptide from the C-terminal of human HeLa thymidine kinase 1 (TK1) enzyme. The anti-TK1 IgY antibody was purified using affinity chromatography against the 31-amino acid peptide. The purified antibody inhibited the catalytic activity of the TK1 enzyme in the CEM TK1(+) cells and recognized the 25-kDa subunit and tetrameric form of TK1, which has a pI value of 8.3. No immunoreaction was observed in CEM TK1(-) cells. Western blot of the serum TK1 (S-TK1) also showed that only a single band was found in the serum of patients with malignancies. No band was seen in healthy serum. Furthermore, dot blots and enhanced chemiluminescence (ECL) detection of S-TK1 performed on sera of preoperative patients with gastric cancer (GC) (n=31) and healthy controls (n=62) showed that the levels of S-TK1 in the sera of cancer patients were significantly different (Pstage cancer patients (four breast carcinomas, three hepatocarcinomas and four thyroid carcinomas) indicated that a strong staining of TK1 enzyme was found in the cytoplasm of malignant cells. No staining or weak staining was seen in normal tissues. We suggest that screening for TK1 using anti-TK1 IgY may be potentially useful for serological and immunohistochemical detection of TK1 as an early prognosis and for monitoring patients undergoing treatment.

  4. Detection of Shiga toxin-producing Escherichia coli by sandwich enzyme-linked immunosorbent assay using chicken egg yolk IgY antibodies

    Directory of Open Access Journals (Sweden)

    Yanil R Parma

    2012-06-01

    Full Text Available Enterohemorrhagic Escherichia coli (EHEC, a subset of Shiga toxin producing E. coli (STEC is associated with a spectrum of diseases that includes diarrhea, hemorrhagic colitis and a life-threatening hemolytic uremic syndrome (HUS. Regardless of serotype, Shiga toxins (Stx1 and/or Stx2 are uniformly expressed by all EHEC, and so exploitable targets for laboratory diagnosis of these pathogens. In this study, a sandwich ELISA for determination of Shiga toxin (Stx was developed using anti-Stx2 B subunit antibodies and its performance was compared with that of the Vero cell assay and a commercial immunoassay kit. Chicken IgY was used as capture antibody and a HRP-conjugated rabbit IgG as the detection antibody. The anti-Stx2B IgY was harvested from eggs laid by hens immunized with a recombinant protein fragment. Several parameters were tested in order to optimize the sandwich ELISA assay, including concentration of antibodies, type and concentration of blocking agent, and incubation temperatures. Supernatants from 42 STEC strains of different serotypes and stx variants, including stx2EDL933, stx2vha, stx2vhb, stx2g, stx1EDL933 and stx1d were tested. All Stx variants were detected by the sandwich ELISA, with a detection limit of 400 ng /ml Stx2. Twenty three strains negative for stx genes, including different bacteria species, showed no activity in Vero cell assay and produced negative results in ELISA, except for 2 strains. Our results show that anti-Stx2B IgY sandwich ELISA could be used in routine diagnosis as a rapid, specific and economic method for detection of Shiga toxin-producing E. coli.

  5. Detection of Shiga toxin-producing Escherichia coli by sandwich enzyme-linked immunosorbent assay using chicken egg yolk IgY antibodies

    Science.gov (United States)

    Parma, Y. R.; Chacana, P. A.; Lucchesi, P. M. A.; Rogé, A.; Granobles Velandia, C. V.; Krüger, A.; Parma, A. E.; Fernández-Miyakawa, M. E.

    2012-01-01

    Enterohemorrhagic Escherichia coli (EHEC), a subset of Shiga toxin producing E. coli (STEC) is associated with a spectrum of diseases that includes diarrhea, hemorrhagic colitis and a life-threatening hemolytic-uremic syndrome (HUS). Regardless of serotype, Shiga toxins (Stx1 and/or Stx2) are uniformly expressed by all EHEC, and so exploitable targets for laboratory diagnosis of these pathogens. In this study, a sandwich ELISA for determination of Shiga toxin (Stx) was developed using anti-Stx2B subunit antibodies and its performance was compared with that of the Vero cell assay and a commercial immunoassay kit. Chicken IgY was used as capture antibody and a HRP-conjugated rabbit IgG as the detection antibody. The anti-Stx2B IgY was harvested from eggs laid by hens immunized with a recombinant protein fragment. Several parameters were tested in order to optimize the sandwich ELISA assay, including concentration of antibodies, type and concentration of blocking agent, and incubation temperatures. Supernatants from 42 STEC strains of different serotypes and stx variants, including stx2EDL933, stx2vha, stx2vhb, stx2g, stx1EDL933, and stx1d were tested. All Stx variants were detected by the sandwich ELISA, with a detection limit of 115 ng/ml Stx2. Twenty three strains negative for stx genes, including different bacteria species, showed no activity in Vero cell assay and produced negative results in ELISA, except for two strains. Our results show that anti-Stx2B IgY sandwich ELISA could be used in routine diagnosis as a rapid, specific and economic method for detection of Shiga toxin-producing E. coli. PMID:22919675

  6. PRODUCTION AND PURIFICATION OF IgY ANTIBODIES AS A NOVEL TOOL TO PURIFY THE NR1 SUBUNIT OF NMDA RECEPTO

    Directory of Open Access Journals (Sweden)

    Edgar Antonio Reyes Montaño

    2011-12-01

    Full Text Available Producing polyclonal antibodies (IgY inchickens has advantages over those obtainedin other animal models, since theyhave been used as a tool for studyingdifferent proteins (NMDA glutamate receptorin our case, specifically the NR1subunit. We produced specific antibodiesagainst expression products by thealternative splicing of the gene encodingNMDA receptor NR1 subunit in adult ratbrain. Three peptides corresponding tothe splicing sites (N1, C1 and C2’ cassetteswere designed, synthesised and usedindividually as antigens in hens. Specificimmunoglobulins were purified fromyolks. The antibodies were then used forpurifying the NMDA receptor NR1 subunitusing affinity chromatography couplingthe three antibodies to the support.R

  7. Hen egg yolk antibodies (IgY), production and use for passive immunization against bacterial enteric infections in chicken : a review

    OpenAIRE

    Chalghoumi, Raja; Beckers, Yves; Portetelle, Daniel; Thewis, André

    2009-01-01

    Les anticorps du jaune d’oeuf de poule (IgY), production et utilisation en immunisation passive contre les infections entériques bactériennes : une revue. Les infections entériques causées par Salmonella constituent un problème majeur de santé publique à travers le monde. Il est bien connu que la volaille, en particulier le poulet de chair, constitue le principal réservoir pour ce pathogène zoonotique. Par conséquent, la prévention et la surveillance de Salmonella au cours de la phase d’éleva...

  8. Therapeutic potential of anti-IL-1β IgY in guinea pigs with allergic asthma induced by ovalbumin.

    Science.gov (United States)

    Wei-xu, Hu; Qin, Xiang; Zhu, Wen; Yuan-yi, Chen; Li-feng, Zeng; Zhi-yong, Liu; Dan, He; Xiao-mu, Wu; Guo-zhu, Hu

    2014-03-01

    Interleukin-1 beta (IL-1β) plays pivotal roles in the progression of allergic airway inflammation. This study aims to determine whether the blockade of IL-1β can inhibit airway inflammation in guinea pigs with allergic asthma induced by the inhalation of aerosolized ovalbumin (OVA). Healthy guinea pigs treated with saline were used as normal controls (group C). The guinea pigs with allergic asthma induced by the inhalation of aerosolized OVA were randomly divided into three groups: (1) the M group containing negative control animals treated with saline; (2) the Z1 group containing animals treated by the inhalation of atomized 0.1% anti-IL-1β immunoglobulin yolk (IgY); and (3) the Z2 group containing positive control animals that were treated with budesonide. The inflammatory cells in the peripheral blood (PB) and bronchoalveolar lavage fluid (BALF) were evaluated using methylene blue and eosin staining. Cytokine concentrations were measured using an enzyme-linked immunosorbent assay. Pulmonary sections were examined using hematoxylin-eosin staining. Allergic inflammation and damage to the pulmonary tissues were decreased in the Z1 group compared to the M group. Eosinophils and neutrophils in the PB and BALF were significantly decreased in the Z1 group compared to the M group (Pguinea pigs with allergic asthma. The inhibitory activity may be due to the decrease in the numbers of eosinophils and neutrophils and the reduced levels of inflammatory cytokines and IgE in the PB and BALF. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Radioisotope instruments

    CERN Document Server

    Cameron, J F; Silverleaf, D J

    1971-01-01

    International Series of Monographs in Nuclear Energy, Volume 107: Radioisotope Instruments, Part 1 focuses on the design and applications of instruments based on the radiation released by radioactive substances. The book first offers information on the physical basis of radioisotope instruments; technical and economic advantages of radioisotope instruments; and radiation hazard. The manuscript then discusses commercial radioisotope instruments, including radiation sources and detectors, computing and control units, and measuring heads. The text describes the applications of radioisotop

  10. Three IgH isotypes, IgM, IgA and IgY are expressed in Gentoo penguin and zebra finch.

    Directory of Open Access Journals (Sweden)

    Binyue Han

    Full Text Available Previous studies on a limited number of birds suggested that the IgD-encoding gene was absent in birds. However, one of our recent studies showed that the gene was definitely expressed in the ostrich and emu. Interestingly, we also identified subclass diversification of IgM and IgY in these two birds. To better understand immunoglobulin genes in birds, in this study, we analyzed the immunoglobulin heavy chain genes in the zebra finch (Taeniopygia guttata and Gentoo penguin (Pygoscelis papua, belonging respectively to the order Passeriformes, the most successful bird order in terms of species diversity and numbers, and Sphenisciformes, a relatively primitive avian order. Similar to the results obtained in chickens and ducks, only three genes encoding immunoglobulin heavy chain isotypes, IgM, IgA and IgY, were identified in both species. Besides, we detected a transcript encoding a short membrane-bound IgA lacking the last two CH exons in the Gentoo penguin. We did not find any evidence supporting the presence of IgD gene or subclass diversification of IgM/IgY in penguin or zebra finch. The obtained data in our study provide more insights into the immunoglobulin heavy chain genes in birds and may help to better understand the evolution of immunoglobulin genes in tetrapods.

  11. Three IgH isotypes, IgM, IgA and IgY are expressed in Gentoo penguin and zebra finch

    Science.gov (United States)

    Han, Haitang; Zhao, Yaofeng; Pan, Qingjie; Ren, Liming

    2017-01-01

    Previous studies on a limited number of birds suggested that the IgD-encoding gene was absent in birds. However, one of our recent studies showed that the gene was definitely expressed in the ostrich and emu. Interestingly, we also identified subclass diversification of IgM and IgY in these two birds. To better understand immunoglobulin genes in birds, in this study, we analyzed the immunoglobulin heavy chain genes in the zebra finch (Taeniopygia guttata) and Gentoo penguin (Pygoscelis papua), belonging respectively to the order Passeriformes, the most successful bird order in terms of species diversity and numbers, and Sphenisciformes, a relatively primitive avian order. Similar to the results obtained in chickens and ducks, only three genes encoding immunoglobulin heavy chain isotypes, IgM, IgA and IgY, were identified in both species. Besides, we detected a transcript encoding a short membrane-bound IgA lacking the last two CH exons in the Gentoo penguin. We did not find any evidence supporting the presence of IgD gene or subclass diversification of IgM/IgY in penguin or zebra finch. The obtained data in our study provide more insights into the immunoglobulin heavy chain genes in birds and may help to better understand the evolution of immunoglobulin genes in tetrapods. PMID:28403146

  12. Quantification of antibody (IgY) titers in hen eggs following immunization and their use in detecting cell surface molecules on nitrocellulose membranes.

    Science.gov (United States)

    Ruan, Guang-Ping; Ma, Li; Meng, Xiao-Jing; Meng, Min-Jie; Wang, Xiao-Ning; Lin, Ying; Wu, Zheng-Qiang; He, Xiao-Wei; Wang, Ju-Fang; Zhu, Yong

    2007-01-01

    HLA-A*0201 alpha chain and beta2m were expressed from a prokaryotic system, and after refolding and purification, the alpha chain and beta2m were used to immunize eight laying hens. The titer of egg yolk antibody against alpha chain increased from 10(2) to 10(5.3) The titer of egg yolk antibody against beta2m increased from 10(1) to 10(4.7). The extent of titer increase is similar between the two antigens. An average of 135 mg purified polyclonal antibody (IgY) can be easily obtained from one egg yolk. The use of egg collection rather than serum collection is compatible with modern animal protection regulations. An average of 28 eggs were obtained from a laying hen every month, with a total amount of 3780 mg immunoglobulin extracted from one immunized hen every month, which would be equivalent to 630 mL of serum or 1260 mL of blood per month. Chickens are an optimal host for the production of polyclonal antibodies with high titer and high yield. Purified IgY was labeled with horseradish peroxidase and reacted with PBMC on nitrocellulose membranes indicating that the antibody can bind to the native conformation of class I HLA molecule on PBMC.

  13. Three IgH isotypes, IgM, IgA and IgY are expressed in Gentoo penguin and zebra finch.

    Science.gov (United States)

    Han, Binyue; Li, Yan; Han, Haitang; Zhao, Yaofeng; Pan, Qingjie; Ren, Liming

    2017-01-01

    Previous studies on a limited number of birds suggested that the IgD-encoding gene was absent in birds. However, one of our recent studies showed that the gene was definitely expressed in the ostrich and emu. Interestingly, we also identified subclass diversification of IgM and IgY in these two birds. To better understand immunoglobulin genes in birds, in this study, we analyzed the immunoglobulin heavy chain genes in the zebra finch (Taeniopygia guttata) and Gentoo penguin (Pygoscelis papua), belonging respectively to the order Passeriformes, the most successful bird order in terms of species diversity and numbers, and Sphenisciformes, a relatively primitive avian order. Similar to the results obtained in chickens and ducks, only three genes encoding immunoglobulin heavy chain isotypes, IgM, IgA and IgY, were identified in both species. Besides, we detected a transcript encoding a short membrane-bound IgA lacking the last two CH exons in the Gentoo penguin. We did not find any evidence supporting the presence of IgD gene or subclass diversification of IgM/IgY in penguin or zebra finch. The obtained data in our study provide more insights into the immunoglobulin heavy chain genes in birds and may help to better understand the evolution of immunoglobulin genes in tetrapods.

  14. The Grism Lens-amplified Survey from Space (GLASS). IV. Mass Reconstruction of the Lensing Cluster Abell 2744 from Frontier Field Imaging and GLASS Spectroscopy

    Science.gov (United States)

    Wang, X.; Hoag, A.; Huang, K.-H.; Treu, T.; Bradač, M.; Schmidt, K. B.; Brammer, G. B.; Vulcani, B.; Jones, T. A.; Ryan, R. E., Jr.; Amorín, R.; Castellano, M.; Fontana, A.; Merlin, E.; Trenti, M.

    2015-09-01

    We present a strong and weak lensing reconstruction of the massive cluster Abell 2744, the first cluster for which deep Hubble Frontier Fields (HFF) images and spectroscopy from the Grism Lens-Amplified Survey from Space (GLASS) are available. By performing a targeted search for emission lines in multiply imaged sources using the GLASS spectra, we obtain five high-confidence spectroscopic redshifts and two tentative ones. We confirm one strongly lensed system by detecting the same emission lines in all three multiple images. We also search for additional line emitters blindly and use the full GLASS spectroscopic catalog to test reliability of photometric redshifts for faint line emitters. We see a reasonable agreement between our photometric and spectroscopic redshift measurements, when including nebular emission in photometric redshift estimations. We introduce a stringent procedure to identify only secure multiple image sets based on colors, morphology, and spectroscopy. By combining 7 multiple image systems with secure spectroscopic redshifts (at 5 distinct redshift planes) with 18 multiple image systems with secure photometric redshifts, we reconstruct the gravitational potential of the cluster pixellated on an adaptive grid, using a total of 72 images. The resulting mass map is compared with a stellar mass map obtained from the deep Spitzer Frontier Fields data to study the relative distribution of stars and dark matter in the cluster. We find that the stellar to total mass ratio varies substantially across the cluster field, suggesting that stars do not trace exactly the total mass in this interacting system. The maps of convergence, shear, and magnification are made available in the standard HFF format.

  15. THE GRISM LENS-AMPLIFIED SURVEY FROM SPACE (GLASS). V. EXTENT AND SPATIAL DISTRIBUTION OF STAR FORMATION IN z ∼ 0.5 CLUSTER GALAXIES

    International Nuclear Information System (INIS)

    Vulcani, Benedetta; Treu, Tommaso; Malkan, Matthew; Abramson, Louis; Schmidt, Kasper B.; Poggianti, Bianca M.; Dressler, Alan; Fontana, Adriano; Pentericci, Laura; Bradac, Marusa; Hoag, Austin; Huang, Kuan-Han; He, Julie; Brammer, Gabriel B.; Trenti, Michele; Linden, Anja von der; Morris, Glenn

    2015-01-01

    We present the first study of the spatial distribution of star formation in z ∼ 0.5 cluster galaxies. The analysis is based on data taken with the Wide Field Camera 3 as part of the Grism Lens-Amplified Survey from Space (GLASS). We illustrate the methodology by focusing on two clusters (MACS 0717.5+3745 and MACS 1423.8+2404) with different morphologies (one relaxed and one merging) and use foreground and background galaxies as a field control sample. The cluster+field sample consists of 42 galaxies with stellar masses in the range 10 8 –10 11 M ⊙  and star formation rates in the range 1–20 M ⊙ yr −1 . Both in clusters and in the field, Hα is more extended than the rest-frame UV continuum in 60% of the cases, consistent with diffuse star formation and inside-out growth. In ∼20% of the cases, the Hα emission appears more extended in cluster galaxies than in the field, pointing perhaps to ionized gas being stripped and/or star formation being enhanced at large radii. The peak of the Hα emission and that of the continuum are offset by less than 1 kpc. We investigate trends with the hot gas density as traced by the X-ray emission, and with the surface mass density as inferred from gravitational lens models, and find no conclusive results. The diversity of morphologies and sizes observed in Hα illustrates the complexity of the environmental processes that regulate star formation. Upcoming analysis of the full GLASS data set will increase our sample size by almost an order of magnitude, verifying and strengthening the inference from this initial data set

  16. THE GRISM LENS-AMPLIFIED SURVEY FROM SPACE (GLASS). IV. MASS RECONSTRUCTION OF THE LENSING CLUSTER ABELL 2744 FROM FRONTIER FIELD IMAGING AND GLASS SPECTROSCOPY

    Energy Technology Data Exchange (ETDEWEB)

    Wang, X.; Schmidt, K. B.; Jones, T. A. [Department of Physics, University of California, Santa Barbara, CA 93106-9530 (United States); Hoag, A.; Huang, K.-H.; Bradac, M. [Department of Physics, University of California, Davis, CA 95616 (United States); Treu, T. [Department of Physics and Astronomy, UCLA, Los Angeles, CA 90095-1547 (United States); Brammer, G. B.; Ryan, R. E. Jr. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD, 21218 (United States); Vulcani, B. [Kavli Institute for the Physics and Mathematics of the Universe (WPI), The University of Tokyo Institutes for Advanced Study (UTIAS), the University of Tokyo, Kashiwa, 277-8582 (Japan); Amorín, R.; Castellano, M.; Fontana, A.; Merlin, E. [INAF—Osservatorio Astronomico di Roma Via Frascati 33, I-00040 Monte Porzio Catone (Italy); Trenti, M., E-mail: xinwang@physics.ucsb.edu [School of Physics, The University of Melbourne, VIC 3010 (Australia)

    2015-09-20

    We present a strong and weak lensing reconstruction of the massive cluster Abell 2744, the first cluster for which deep Hubble Frontier Fields (HFF) images and spectroscopy from the Grism Lens-Amplified Survey from Space (GLASS) are available. By performing a targeted search for emission lines in multiply imaged sources using the GLASS spectra, we obtain five high-confidence spectroscopic redshifts and two tentative ones. We confirm one strongly lensed system by detecting the same emission lines in all three multiple images. We also search for additional line emitters blindly and use the full GLASS spectroscopic catalog to test reliability of photometric redshifts for faint line emitters. We see a reasonable agreement between our photometric and spectroscopic redshift measurements, when including nebular emission in photometric redshift estimations. We introduce a stringent procedure to identify only secure multiple image sets based on colors, morphology, and spectroscopy. By combining 7 multiple image systems with secure spectroscopic redshifts (at 5 distinct redshift planes) with 18 multiple image systems with secure photometric redshifts, we reconstruct the gravitational potential of the cluster pixellated on an adaptive grid, using a total of 72 images. The resulting mass map is compared with a stellar mass map obtained from the deep Spitzer Frontier Fields data to study the relative distribution of stars and dark matter in the cluster. We find that the stellar to total mass ratio varies substantially across the cluster field, suggesting that stars do not trace exactly the total mass in this interacting system. The maps of convergence, shear, and magnification are made available in the standard HFF format.

  17. THE GRISM LENS-AMPLIFIED SURVEY FROM SPACE (GLASS). V. EXTENT AND SPATIAL DISTRIBUTION OF STAR FORMATION IN z ∼ 0.5 CLUSTER GALAXIES

    Energy Technology Data Exchange (ETDEWEB)

    Vulcani, Benedetta [Kavli Institute for the Physics and Mathematics of the Universe (WPI), The University of Tokyo Institutes for Advanced Study (UTIAS), the University of Tokyo, Kashiwa, 277-8582 (Japan); Treu, Tommaso; Malkan, Matthew; Abramson, Louis [Department of Physics and Astronomy, University of California, Los Angeles, CA 90095-1547 (United States); Schmidt, Kasper B. [Department of Physics, University of California, Santa Barbara, CA 93106-9530 (United States); Poggianti, Bianca M. [INAF-Astronomical Observatory of Padova (Italy); Dressler, Alan [The Observatories of the Carnegie Institution for Science, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Fontana, Adriano; Pentericci, Laura [INAF—Osservatorio Astronomico di Roma, Via Frascati 33, 00040 Monte Porzio Catone (Italy); Bradac, Marusa; Hoag, Austin; Huang, Kuan-Han; He, Julie [Department of Physics, University of California, Davis, CA 95616 (United States); Brammer, Gabriel B. [Space Telescope Science Institute, 3700 San Martin Drive, Baltimore, MD 21218 (United States); Trenti, Michele [School of Physics, University of Melbourne, VIC 3010 (Australia); Linden, Anja von der [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen Juliane Maries Vej 30, DK-2100 Copenhagen Ø (Denmark); Morris, Glenn [Kavli Institute for Particle Astrophysics and Cosmology, Stanford University, 452 Lomita Mall, Stanford, CA 94305-4085 (United States)

    2015-12-01

    We present the first study of the spatial distribution of star formation in z ∼ 0.5 cluster galaxies. The analysis is based on data taken with the Wide Field Camera 3 as part of the Grism Lens-Amplified Survey from Space (GLASS). We illustrate the methodology by focusing on two clusters (MACS 0717.5+3745 and MACS 1423.8+2404) with different morphologies (one relaxed and one merging) and use foreground and background galaxies as a field control sample. The cluster+field sample consists of 42 galaxies with stellar masses in the range 10{sup 8}–10{sup 11} M{sub ⊙} and star formation rates in the range 1–20 M{sub ⊙} yr{sup −1}. Both in clusters and in the field, Hα is more extended than the rest-frame UV continuum in 60% of the cases, consistent with diffuse star formation and inside-out growth. In ∼20% of the cases, the Hα emission appears more extended in cluster galaxies than in the field, pointing perhaps to ionized gas being stripped and/or star formation being enhanced at large radii. The peak of the Hα emission and that of the continuum are offset by less than 1 kpc. We investigate trends with the hot gas density as traced by the X-ray emission, and with the surface mass density as inferred from gravitational lens models, and find no conclusive results. The diversity of morphologies and sizes observed in Hα illustrates the complexity of the environmental processes that regulate star formation. Upcoming analysis of the full GLASS data set will increase our sample size by almost an order of magnitude, verifying and strengthening the inference from this initial data set.

  18. The 3D-HST Survey: Hubble Space Telescope WFC3/G141 Grism Spectra, Redshifts, and Emission Line Measurements for ~ 100,000 Galaxies

    Science.gov (United States)

    Momcheva, Ivelina G.; Brammer, Gabriel B.; van Dokkum, Pieter G.; Skelton, Rosalind E.; Whitaker, Katherine E.; Nelson, Erica J.; Fumagalli, Mattia; Maseda, Michael V.; Leja, Joel; Franx, Marijn; Rix, Hans-Walter; Bezanson, Rachel; Da Cunha, Elisabete; Dickey, Claire; Förster Schreiber, Natascha M.; Illingworth, Garth; Kriek, Mariska; Labbé, Ivo; Ulf Lange, Johannes; Lundgren, Britt F.; Magee, Daniel; Marchesini, Danilo; Oesch, Pascal; Pacifici, Camilla; Patel, Shannon G.; Price, Sedona; Tal, Tomer; Wake, David A.; van der Wel, Arjen; Wuyts, Stijn

    2016-08-01

    We present reduced data and data products from the 3D-HST survey, a 248-orbit HST Treasury program. The survey obtained WFC3 G141 grism spectroscopy in four of the five CANDELS fields: AEGIS, COSMOS, GOODS-S, and UDS, along with WFC3 H 140 imaging, parallel ACS G800L spectroscopy, and parallel I 814 imaging. In a previous paper, we presented photometric catalogs in these four fields and in GOODS-N, the fifth CANDELS field. Here we describe and present the WFC3 G141 spectroscopic data, again augmented with data from GO-1600 in GOODS-N (PI: B. Weiner). We developed software to automatically and optimally extract interlaced two-dimensional (2D) and one-dimensional (1D) spectra for all objects in the Skelton et al. (2014) photometric catalogs. The 2D spectra and the multi-band photometry were fit simultaneously to determine redshifts and emission line strengths, taking the morphology of the galaxies explicitly into account. The resulting catalog has redshifts and line strengths (where available) for 22,548 unique objects down to {{JH}}{IR}≤slant 24 (79,609 unique objects down to {{JH}}{IR}≤slant 26). Of these, 5459 galaxies are at z\\gt 1.5 and 9621 are at 0.7\\lt z\\lt 1.5, where Hα falls in the G141 wavelength coverage. The typical redshift error for {{JH}}{IR}≤slant 24 galaxies is {σ }z≈ 0.003× (1+z), I.e., one native WFC3 pixel. The 3σ limit for emission line fluxes of point sources is 2.1× {10}-17 erg s-1 cm-2. All 2D and 1D spectra, as well as redshifts, line fluxes, and other derived parameters, are publicly available.18

  19. Obtención, purificación y caracterización de anticuerpos policlonales IgY desarrollados en gallina, dirigidos contra aislamientos colombianos de Giardia duodenalis.

    Directory of Open Access Journals (Sweden)

    Dabeiba Adriana García

    2005-12-01

    Full Text Available Introducción. El desarrollo de anticuerpos policlonales requiere de animales de laboratorio, generalmente, el conejo, que deben sangrarse para su obtención. Como alternativa, se han utilizado las gallinas. Objetivo. Desarrollar anticuerpos policlonales IgY anti-Giardia duodenalis y evaluar diferentes métodos para su purificación a partir de yema de huevo. Materiales y métodos. Se inmunizaron tres gallinas intramuscularmente con trofozoítos del parásito: las inmunizaciones se realizaron a los 0, 15, 30, 45, 60, 90 y 120 días. Se recolectaron huevos en cada etapa de la inmunización y se purificó la IgY por deslipidación (D y precipitación (P mediante cinco protocolos diferentes: M1: (P: sulfato de amonio/D: dextrán sulfato-cloruro de calcio, M2: (D: dextrán sulfato-cloruro de calcio/P: sulfato de amonio, M3: (D: cloroformo/ P: sulfato de amonio 50%, M4: (D: solución A/P:solución B y M5: (D: cloroformo/P: sulfato de amonio 30%. Se realizó evaluación inmunoquímica de la IgY anti-Giardia duodenalis mediante inmunodifusión, contrainmunoelectroforesis e inmunoelectrotransferencia (Western blot; la pureza de IgY por SDS-PAGE en presencia y ausencia de reductor y la concentración de la inmunoglobulina (mg/mL por espectrofotometría y densitometría. Resultados. La IgY anti-G. duodenalis mediante evaluación inmunoquímica presentó títulos hasta de 1:32. La inmunoglobulina en ausencia de reductor mostró una banda de 180 kd y en su presencia bandas de 30 y 68 kd, características de sus cadenas liviana y pesada, respectivamente. Las mayores concentraciones de inmunoglobulina se recuperaron con el método dos (M2, 4,6 mg de IgY por mL de yema de partida. Conclusiones. Por su facilidad y economía de producción en gallinas, los anticuerpos policlonales IgY anti-Giardia así obtenidos podrán utilizarse para desarrollar inmunoensayos que detecten el parásito en eluídos de heces.

  20. CARACTERIZACIÓN DE IGYS ANTI-LECTINA DE Salvia bogotensis Y SU APLICACIÓN EN ESTUDIOS CITOQUÍMICOS PARA LA DETECCIÓN DEL ANTÍGENO TN

    Directory of Open Access Journals (Sweden)

    Nohora Vega

    2010-02-01

    Full Text Available Las inmunoglobulinas aisladas de la yema de huevo (IgY son muy utilizadas actualmente en diversos campos de las ciencias biológicas, dadas sus ventajas frente a las IgG séricas de mamíferos. En un trabajo previo establecimos las condiciones de obtención de IgY dirigidas contra la lectinas de Salvia bogotensis; su utilización en estudios inmunocitoquímicos requiere conocer sus principales características moleculares y las condiciones para la interacción IgY-lectina. La lectina de Salvia bogotensis (SBoL reconoce específicamente el antígeno Tn, marcador tumoral en muchos tipos de cáncer, pero se requieren herramientas adicionales para evidenciar esta interacción a nivel celular. Dada la disponibilidad de IgY anti-lectina de S. bogotensis, se realizó este trabajo con el objeto de caracterizar molecularmente estas IgY y evaluar su utilización en estudios inmunocitoquímicos para la detección del antígeno Tn en células tumorales. A las IgY purificadas se les determinó su punto isoeléctrico, peso molecular y contenido de carbohidratos. Para establecer la especificidad de interacción IgY-SBoL se obtuvieron lectinas homólogas y heterólogas y se ensayaron por ELLSA. La detección del antígeno Tn en las líneas celulares MCF-7 y HeLa con la lectina y las IgYs marcadas con biotina o peroxidasa se realizó por CELISA e inmunocitoquímica. Los resultados mostraron que los anticuerpos IgY anti-SBoL son una herramienta de una alta sensibilidad para los ensayos de reconocimiento específico del antígeno Tn.

  1. Instrumental interaction

    OpenAIRE

    Luciani , Annie

    2007-01-01

    International audience; The expression instrumental interaction as been introduced by Claude Cadoz to identify a human-object interaction during which a human manipulates a physical object - an instrument - in order to perform a manual task. Classical examples of instrumental interaction are all the professional manual tasks: playing violin, cutting fabrics by hand, moulding a paste, etc.... Instrumental interaction differs from other types of interaction (called symbolic or iconic interactio...

  2. Development of IgY antibodies in chickens and IgG in rabbits immunized against proteins of Pythium insidiosum isolated from horses in the state of Rio de Janeiro Desenvolvimento de Anticorpos IgY em galinhas e IgG em coelhos imunizados contra proteínas de Pythium insidiosum isolado de equinos no Estado do Rio de Janeiro, Brasil

    Directory of Open Access Journals (Sweden)

    Maria Fabíola Nunes Rangel

    2010-01-01

    Full Text Available Pythiosis is caused by Pythium insidiosum and the occurrence of disease in horses was described in the North and Northwest State of Rio de Janeiro, Brazil. The disease was described in cattle, sheep, humans, and horses in different states and regions across the country. This paper describes the development of IgY and IgG polyclonal antibodies, in chicken and rabbits, respectively against proteins extracted from kunkers and hyphae of P. insidiosum from affected horses. The proteins were recognized by chicken, rabbit and horse antibodies by immunodiffusion and Western blot against majority bands of 27 and 43 KDa, and titrated by ELISA. The antibodies IgY developed by the first time against Brazilian strains of P. insidiosum may represent a valuable tool in the detection of antigens of the pathogen and contribute to further studies aimed at immunotherapy and knowledge about this disease in endemic areas in Rio de Janeiro and in Brazil.Pitiose é causada por Pythium insidiosum e a doença foi descrita em equinos no Norte e Noroeste do Estado do Rio de Janeiro, Brasil. A doença foi descrita em bovinos, ovelhas, humanos e cavalos em diferentes estados e regiões do país. Este trabalho descreve o desenvolvimento de anticorpos policlonais, IgY e IgG, em galinha e coelho, respectivamente, contra proteínas extraídas de kunkers e hifas de P. insidiosum de cavalos doentes. As proteínas foram reconhecidas por anticorpos de galinha, coelho e cavalos contra as bandas majoritárias de 27 e 34 KDa em imunodifusão e Western blot tituladas por ELISA. Os anticorpos IgY desenvolvidos pela primeira vez contra cepas brasileiras de P. insidiosum podem representar um valioso instrumento na detecção de antígenos de patógenos e contribuem para novos estudos baseados na imunoterapia e no entendimento sobre esta doença em áreas endêmicas no Rio de Janeiro e em todo o país.

  3. HST Grism Confirmation of 16 Structures at 1.4 < z < 2.8 from the Clusters Around Radio-Loud AGN (CARLA) Survey

    Science.gov (United States)

    Noirot, Gaël; Stern, Daniel; Mei, Simona; Wylezalek, Dominika; Cooke, Elizabeth A.; De Breuck, Carlos; Galametz, Audrey; Hatch, Nina A.; Vernet, Joël; Brodwin, Mark; Eisenhardt, Peter; Gonzalez, Anthony H.; Jarvis, Matt; Rettura, Alessandro; Seymour, Nick; Stanford, S. A.

    2018-05-01

    We report spectroscopic results from our 40-orbit Hubble Space Telescope slitless grism spectroscopy program observing the 20 densest Clusters Around Radio-Loud AGN (CARLA) candidate galaxy clusters at 1.4 targeting 420 distant radio-loud AGN. We report the spectroscopic confirmation of 16 distant structures at 1.4 targeted powerful high-redshift radio-loud AGN. We also report the serendipitous discovery and spectroscopic confirmation of seven additional structures at 0.87 targeted radio-loud AGN. We find that 1010–1011 M ⊙ member galaxies of our confirmed CARLA structures form significantly fewer stars than their field counterparts at all redshifts within 1.4 ≤ z ≤ 2. We also observe higher star-forming activity in the structure cores up to z = 2, finding similar trends as cluster surveys at slightly lower redshifts (1.0 strategy of obtaining just two grism orbits per field only obtains spectroscopic confirmation of emission line galaxies. Deeper spectroscopy will be required to study the population of evolved, massive galaxies in these (forming) clusters. Lacking multi-band coverage of the fields, we adopt a very conservative approach of calling all confirmations “structures,” although we note that a number of features are consistent with some of them being bona fide galaxy clusters. Together this survey represents a unique and large homogenous sample of spectroscopically confirmed structures at high redshifts, potentially more than doubling the census of confirmed, massive clusters at z > 1.4.

  4. A trial with IgY chicken antibodies to eradicate faecal carriage of Klebsiella pneumoniae and Escherichia coli producing extended-spectrum beta-lactamases

    Directory of Open Access Journals (Sweden)

    Anna-Karin Jonsson

    2015-11-01

    Full Text Available Background: Extended-spectrum beta-lactamase (ESBL-producing Enterobacteriaceae is an emerging therapeutic challenge, especially in the treatment of urinary tract infections. Following an outbreak of CTX-M-15 Klebsiella pneumoniae in Uppsala, Sweden, an orphan drug trial on IgY chicken antibodies was undertaken in an attempt to eradicate faecal carriage of ESBL-producing K. pneumoniae and Escherichia coli. Methods: Hens were immunised with epitopes from freeze-dried, whole-cell bacteria (ESBL-producing K. pneumoniae and E. coli and recombinant proteins of two K. pneumoniae fimbriae subunits (fimH and mrkD. The egg yolks were processed according to good manufacturing practice and the product was stored at−20°C until used. Using an internal database from the outbreak and the regular laboratory database, faecal carriers were identified and recruited from May 2005 to December 2013. The participants were randomised in a placebo-controlled 1:1 manner. Results: From 749 eligible patients, 327 (44% had deceased, and only 91 (12% were recruited and signed the informed consent. In the initial screening performed using the polymerase chain reaction, 24 participants were ESBL positive and subsequently randomised and treated with either the study drug or a placebo. The study was powered for 124 participants. Because of a very high dropout rate, the study was prematurely terminated. From the outbreak cohort (n=247, only eight patients were screened, and only one was positive with the outbreak strain in faeces. Conclusions: The present study design, using IgY chicken antibodies for the eradication of ESBL-producing K. pneumonia and E. coli, was ineffective in reaching its goal due to high mortality and other factors resulting in a low inclusion rate. Spontaneous eradication of ESBL-producing bacteria was frequently observed in recruited participants, which is consistent with previous reports.

  5. A trial with IgY chicken antibodies to eradicate faecal carriage of Klebsiella pneumoniae and Escherichia coli producing extended-spectrum beta-lactamases

    Science.gov (United States)

    Jonsson, Anna-Karin; Larsson, Anders; Tängdén, Thomas; Melhus, Åsa; Lannergård, Anders

    2015-01-01

    Background Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae is an emerging therapeutic challenge, especially in the treatment of urinary tract infections. Following an outbreak of CTX-M-15 Klebsiella pneumoniae in Uppsala, Sweden, an orphan drug trial on IgY chicken antibodies was undertaken in an attempt to eradicate faecal carriage of ESBL-producing K. pneumoniae and Escherichia coli. Methods Hens were immunised with epitopes from freeze-dried, whole-cell bacteria (ESBL-producing K. pneumoniae and E. coli) and recombinant proteins of two K. pneumoniae fimbriae subunits (fimH and mrkD). The egg yolks were processed according to good manufacturing practice and the product was stored at−20°C until used. Using an internal database from the outbreak and the regular laboratory database, faecal carriers were identified and recruited from May 2005 to December 2013. The participants were randomised in a placebo-controlled 1:1 manner. Results From 749 eligible patients, 327 (44%) had deceased, and only 91 (12%) were recruited and signed the informed consent. In the initial screening performed using the polymerase chain reaction, 24 participants were ESBL positive and subsequently randomised and treated with either the study drug or a placebo. The study was powered for 124 participants. Because of a very high dropout rate, the study was prematurely terminated. From the outbreak cohort (n=247), only eight patients were screened, and only one was positive with the outbreak strain in faeces. Conclusions The present study design, using IgY chicken antibodies for the eradication of ESBL-producing K. pneumonia and E. coli, was ineffective in reaching its goal due to high mortality and other factors resulting in a low inclusion rate. Spontaneous eradication of ESBL-producing bacteria was frequently observed in recruited participants, which is consistent with previous reports. PMID:26560861

  6. Instrumentation Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Provides instrumentation support for flight tests of prototype weapons systems using a vast array of airborne sensors, transducers, signal conditioning and encoding...

  7. Instrumentation development

    International Nuclear Information System (INIS)

    Ubbes, W.F.; Yow, J.L. Jr.

    1988-01-01

    Instrumentation is developed for the Civilian Radioactive Waste Management Program to meet several different (and sometimes conflicting) objectives. This paper addresses instrumentation development for data needs that are related either directly or indirectly to a repository site, but does not touch on instrumentation for work with waste forms or other materials. Consequently, this implies a relatively large scale for the measurements, and an in situ setting for instrument performance. In this context, instruments are needed for site characterization to define phenomena, develop models, and obtain parameter values, and for later design and performance confirmation testing in the constructed repository. The former set of applications is more immediate, and is driven by the needs of program design and performance assessment activities. A host of general technical and nontechnical issues have arisen to challenge instrumentation development. Instruments can be classed into geomechanical, geohydrologic, or other specialty categories, but these issues cut across artificial classifications. These issues are outlined. Despite this imposing list of issues, several case histories are cited to evaluate progress in the area

  8. Instrumental analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seung Jae; Seo, Seong Gyu

    1995-03-15

    This textbook deals with instrumental analysis, which consists of nine chapters. It has Introduction of analysis chemistry, the process of analysis and types and form of the analysis, Electrochemistry on basic theory, potentiometry and conductometry, electromagnetic radiant rays and optical components on introduction and application, Ultraviolet rays and Visible spectrophotometry, Atomic absorption spectrophotometry on introduction, flame emission spectrometry and plasma emission spectrometry. The others like infrared spectrophotometry, X-rays spectrophotometry and mass spectrometry, chromatography and the other instrumental analysis like radiochemistry.

  9. Instrumental analysis

    International Nuclear Information System (INIS)

    Kim, Seung Jae; Seo, Seong Gyu

    1995-03-01

    This textbook deals with instrumental analysis, which consists of nine chapters. It has Introduction of analysis chemistry, the process of analysis and types and form of the analysis, Electrochemistry on basic theory, potentiometry and conductometry, electromagnetic radiant rays and optical components on introduction and application, Ultraviolet rays and Visible spectrophotometry, Atomic absorption spectrophotometry on introduction, flame emission spectrometry and plasma emission spectrometry. The others like infrared spectrophotometry, X-rays spectrophotometry and mass spectrometry, chromatography and the other instrumental analysis like radiochemistry.

  10. LOFT instrumentation

    International Nuclear Information System (INIS)

    Bixby, W.W.

    1979-01-01

    A description of instrumentation used in the Loss-of-Fluid Test (LOFT) large break Loss-of-Coolant Experiments is presented. Emphasis is placed on hydraulic and thermal measurements in the primary system piping and components, reactor vessel, and pressure suppression system. In addition, instrumentation which is being considered for measurement of phenomena during future small break testing is discussed. (orig.) 891 HP/orig. 892 BRE [de

  11. Chicken IgY Fc linked to Bordetella avium ompA and Taishan Pinus massoniana pollen polysaccharide adjuvant enhances macrophage function and specific immune responses

    Directory of Open Access Journals (Sweden)

    Zhu Ruiliang

    2016-11-01

    Full Text Available Fc-fusion technologies, in which immunoglobulin Fc is genetically fused to an antigenic protein, have been developed to confer antibody-like properties to proteins and peptides. Mammalian IgG Fc fusion exhibits improved antigen-induced immune responses by providing aggregates with high avidity for the IgG Fc receptor and salvaging the antigenic portion from endosomal degradation. However, whether the linked chicken IgY Fc fragment shares similar characteristics to mammalian IgG Fc remains unclear. In this study, we linked the chicken IgY Fc gene to the outer membrane protein A (ompA of Borderella avium through overlapping PCR. The fusion gene was cloned into the pPIC9 plasmid to construct the recombinant Pichia pastoris transformant expressing the ompA–Fc fusion protein. The effects of the linked Fc on macrophage vitality, activity, efficiency of antigen processing, and immune responses induced by the fused ompA were investigated. Furthermore, the effect of Taishan Pinus massoniana pollen polysaccharide (TPPPS, an immunomodulator, on chicken macrophage activation was evaluated. TPPPS was also used as an adjuvant to investigate its immunomodulatory effect on immunoresponses induced by the fused ompA–Fc in chickens. The pinocytosis, phagocytosis, secretion of nitric oxide and TNF-α, and MHC-II molecular expression of the macrophages treated with the fused ompA–Fc were significantly higher than those of the macrophages treated with ompA alone. The addition of TPPPS to the fused ompA–Fc further enhanced macrophage functions. The fused ompA–Fc elicited higher antigen-specific immune responses and protective efficacy compared with ompA alone. Moreover, the fused ompA–Fc conferred higher serum antibody titers, serum IL-2 and IL-4 concentrations, CD4+ and CD8+ T-lymphocyte counts, lymphocyte transformation rate, and protection rate compared with ompA alone. Notably, the prepared TPPPS adjuvant ompA–Fc vaccines induced high immune

  12. Anti-HER2 IgY antibody-functionalized single-walled carbon nanotubes for detection and selective destruction of breast cancer cells

    Directory of Open Access Journals (Sweden)

    Mitra Somenath

    2009-10-01

    Full Text Available Abstract Background Nanocarrier-based antibody targeting is a promising modality in therapeutic and diagnostic oncology. Single-walled carbon nanotubes (SWNTs exhibit two unique optical properties that can be exploited for these applications, strong Raman signal for cancer cell detection and near-infrared (NIR absorbance for selective photothermal ablation of tumors. In the present study, we constructed a HER2 IgY-SWNT complex and demonstrated its dual functionality for both detection and selective destruction of cancer cells in an in vitro model consisting of HER2-expressing SK-BR-3 cells and HER2-negative MCF-7 cells. Methods The complex was constructed by covalently conjugating carboxylated SWNTs with anti-HER2 chicken IgY antibody, which is more specific and sensitive than mammalian IgGs. Raman signals were recorded on Raman spectrometers with a laser excitation at 785 nm. NIR irradiation was performed using a diode laser system, and cells with or without nanotube treatment were irradiated by 808 nm laser at 5 W/cm2 for 2 min. Cell viability was examined by the calcein AM/ethidium homodimer-1 (EthD-1 staining. Results Using a Raman optical microscope, we found the Raman signal collected at single-cell level from the complex-treated SK-BR-3 cells was significantly greater than that from various control cells. NIR irradiation selectively destroyed the complex-targeted breast cancer cells without harming receptor-free cells. The cell death was effectuated without the need of internalization of SWNTs by the cancer cells, a finding that has not been reported previously. Conclusion We have demonstrated that the HER2 IgY-SWNT complex specifically targeted HER2-expressing SK-BR-3 cells but not receptor-negative MCF-7 cells. The complex can be potentially used for both detection and selective photothermal ablation of receptor-positive breast cancer cells without the need of internalization by the cells. Thus, the unique intrinsic properties of SWNTs

  13. Anti-HER2 IgY antibody-functionalized single-walled carbon nanotubes for detection and selective destruction of breast cancer cells

    International Nuclear Information System (INIS)

    Xiao, Yan; Savla, Ronak; Wagner, Paul D; Srivastava, Sudhir; He, Huixin; Gao, Xiugong; Taratula, Oleh; Treado, Stephen; Urbas, Aaron; Holbrook, R David; Cavicchi, Richard E; Avedisian, C Thomas; Mitra, Somenath

    2009-01-01

    Nanocarrier-based antibody targeting is a promising modality in therapeutic and diagnostic oncology. Single-walled carbon nanotubes (SWNTs) exhibit two unique optical properties that can be exploited for these applications, strong Raman signal for cancer cell detection and near-infrared (NIR) absorbance for selective photothermal ablation of tumors. In the present study, we constructed a HER2 IgY-SWNT complex and demonstrated its dual functionality for both detection and selective destruction of cancer cells in an in vitro model consisting of HER2-expressing SK-BR-3 cells and HER2-negative MCF-7 cells. The complex was constructed by covalently conjugating carboxylated SWNTs with anti-HER2 chicken IgY antibody, which is more specific and sensitive than mammalian IgGs. Raman signals were recorded on Raman spectrometers with a laser excitation at 785 nm. NIR irradiation was performed using a diode laser system, and cells with or without nanotube treatment were irradiated by 808 nm laser at 5 W/cm 2 for 2 min. Cell viability was examined by the calcein AM/ethidium homodimer-1 (EthD-1) staining. Using a Raman optical microscope, we found the Raman signal collected at single-cell level from the complex-treated SK-BR-3 cells was significantly greater than that from various control cells. NIR irradiation selectively destroyed the complex-targeted breast cancer cells without harming receptor-free cells. The cell death was effectuated without the need of internalization of SWNTs by the cancer cells, a finding that has not been reported previously. We have demonstrated that the HER2 IgY-SWNT complex specifically targeted HER2-expressing SK-BR-3 cells but not receptor-negative MCF-7 cells. The complex can be potentially used for both detection and selective photothermal ablation of receptor-positive breast cancer cells without the need of internalization by the cells. Thus, the unique intrinsic properties of SWNTs combined with high specificity and sensitivity of IgY

  14. Instrumental Capital

    Directory of Open Access Journals (Sweden)

    Gabriel Valerio

    2007-07-01

    Full Text Available During the history of human kind, since our first ancestors, tools have represented a mean to reach objectives which might otherwise seemed impossibles. In the called New Economy, where tangibles assets appear to be losing the role as the core element to produce value versus knowledge, tools have kept aside man in his dairy work. In this article, the author's objective is to describe, in a simple manner, the importance of managing the organization's group of tools or instruments (Instrumental Capital. The characteristic conditions of this New Economy, the way Knowledge Management deals with these new conditions and the sub-processes that provide support to the management of Instrumental Capital are described.

  15. Innovative instrumentation

    International Nuclear Information System (INIS)

    Anon.

    1983-01-01

    At this year's particle physics conference at Brighton, a parallel session was given over to instrumentation and detector development. While this work is vital to the health of research and its continued progress, its share of prime international conference time is limited. Instrumentation can be innovative three times — first when a new idea is outlined, secondly when it is shown to be feasible, and finally when it becomes productive in a real experiment, amassing useful data rather than operational experience. Hyams' examples showed that it can take a long time for a new idea to filter through these successive stages, if it ever makes it at all

  16. Innovative instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1983-11-15

    At this year's particle physics conference at Brighton, a parallel session was given over to instrumentation and detector development. While this work is vital to the health of research and its continued progress, its share of prime international conference time is limited. Instrumentation can be innovative three times — first when a new idea is outlined, secondly when it is shown to be feasible, and finally when it becomes productive in a real experiment, amassing useful data rather than operational experience. Hyams' examples showed that it can take a long time for a new idea to filter through these successive stages, if it ever makes it at all.

  17. Instrumental aspects

    Directory of Open Access Journals (Sweden)

    Qureshi Navid

    2017-01-01

    Full Text Available Every neutron scattering experiment requires the choice of a suited neutron diffractometer (or spectrometer in the case of inelastic scattering with its optimal configuration in order to accomplish the experimental tasks in the most successful way. Most generally, the compromise between the incident neutron flux and the instrumental resolution has to be considered, which is depending on a number of optical devices which are positioned in the neutron beam path. In this chapter the basic instrumental principles of neutron diffraction will be explained. Examples of different types of experiments and their respective expectable results will be shown. Furthermore, the production and use of polarized neutrons will be stressed.

  18. Surgical Instrument

    NARCIS (Netherlands)

    Dankelman, J.; Horeman, T.

    2009-01-01

    The present invention relates to a surgical instrument for minimall-invasive surgery, comprising a handle, a shaft and an actuating part, characterised by a gastight cover surrounding the shaft, wherein the cover is provided with a coupler that has a feed- through opening with a loskable seal,

  19. Weather Instruments.

    Science.gov (United States)

    Brantley, L. Reed, Sr.; Demanche, Edna L.; Klemm, E. Barbara; Kyselka, Will; Phillips, Edwin A.; Pottenger, Francis M.; Yamamoto, Karen N.; Young, Donald B.

    This booklet presents some activities to measure various weather phenomena. Directions for constructing a weather station are included. Instruments including rain gauges, thermometers, wind vanes, wind speed devices, humidity devices, barometers, atmospheric observations, a dustfall jar, sticky-tape can, detection of gases in the air, and pH of…

  20. Nuclear instrumentation

    International Nuclear Information System (INIS)

    Weill, Jacky; Fabre, Rene.

    1981-01-01

    This article sums up the Research and Development effort at present being carried out in the five following fields of applications: Health physics and Radioprospection, Control of nuclear reactors, Plant control (preparation and reprocessing of the fuel, testing of nuclear substances, etc.), Research laboratory instrumentation, Detectors. It also sets the place of French industrial activities by means of an estimate of the French market, production and flow of trading with other countries [fr

  1. Divided Instruments

    Science.gov (United States)

    Chapman, A.; Murdin, P.

    2000-11-01

    Although the division of the zodiac into 360° probably derives from Egypt or Assyria around 2000 BC, there is no surviving evidence of Mesopotamian cultures embodying this division into a mathematical instrument. Almost certainly, however, it was from Babylonia that the Greek geometers learned of the 360° circle, and by c. 80 BC they had incorporated it into that remarkably elaborate device gener...

  2. Instrumentation development

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    Areas being investigated for instrumentation improvement during low-level pollution monitoring include laser opto-acoustic spectroscopy, x-ray fluorescence spectroscopy, optical fluorescence spectroscopy, liquid crystal gas detectors, advanced forms of atomic absorption spectroscopy, electro-analytical chemistry, and mass spectroscopy. Emphasis is also directed toward development of physical methods, as opposed to conventional chemical analysis techniques for monitoring these trace amounts of pollution related to energy development and utilization

  3. Instrumentation maintenance

    International Nuclear Information System (INIS)

    Mack, D.A.

    1976-09-01

    It is essential to any research activity that accurate and efficient measurements be made for the experimental parameters under consideration for each individual experiment or test. Satisfactory measurements in turn depend upon having the necessary instruments and the capability of ensuring that they are performing within their intended specifications. This latter requirement can only be achieved by providing an adequate maintenance facility, staffed with personnel competent to understand the problems associated with instrument adjustment and repair. The Instrument Repair Shop at the Lawrence Berkeley Laboratory is designed to achieve this end. The organization, staffing and operation of this system is discussed. Maintenance policy should be based on studies of (1) preventive vs. catastrophic maintenance, (2) records indicating when equipment should be replaced rather than repaired and (3) priorities established to indicate the order in which equipment should be repaired. Upon establishing a workable maintenance policy, the staff should be instructed so that they may provide appropriate scheduled preventive maintenance, calibration and corrective procedures, and emergency repairs. The education, training and experience of the maintenance staff is discussed along with the organization for an efficient operation. The layout of the various repair shops is described in the light of laboratory space and financial constraints

  4. Seismic instrumentation

    International Nuclear Information System (INIS)

    1984-06-01

    RFS or Regles Fondamentales de Surete (Basic Safety Rules) applicable to certain types of nuclear facilities lay down requirements with which compliance, for the type of facilities and within the scope of application covered by the RFS, is considered to be equivalent to compliance with technical French regulatory practice. The object of the RFS is to take advantage of standardization in the field of safety, while allowing for technical progress in that field. They are designed to enable the operating utility and contractors to know the rules pertaining to various subjects which are considered to be acceptable by the Service Central de Surete des Installations Nucleaires, or the SCSIN (Central Department for the Safety of Nuclear Facilities). These RFS should make safety analysis easier and lead to better understanding between experts and individuals concerned with the problems of nuclear safety. The SCSIN reserves the right to modify, when considered necessary, any RFS and specify, if need be, the terms under which a modification is deemed retroactive. The aim of this RFS is to define the type, location and operating conditions for seismic instrumentation needed to determine promptly the seismic response of nuclear power plants features important to safety to permit comparison of such response with that used as the design basis

  5. Meteorological instrumentation

    International Nuclear Information System (INIS)

    1982-06-01

    RFS or ''Regles Fondamentales de Surete'' (Basic Safety Rules) applicable to certain types of nuclear facilities lay down requirements with which compliance, for the type of facilities and within the scope of application covered by the RFS, is considered to be equivalent to compliance with technical French regulatory practice. The object of the RFS is to take advantage of standardization in the field of safety , while allowing for technical progress in that field. They are designed to enable the operating utility and contractors to know the rules pertaining to various subjects which are considered to be acceptable by the ''Service Central de Surete des Installations Nucleaires'' or the SCSIN (Central Department for the Safety of Nuclear Facilities). These RFS should make safety analysis easier and lead to better understanding between experts and individuals concerned with the problems of nuclear safety. The SCSIN reserves the right to modify, when considered necessary any RFS and specify, if need be, the terms under which a modification is deemed retroactive. The purpose of this RFS is to specify the meteorological instrumentation required at the site of each nuclear power plant equipped with at least one pressurized water reactor

  6. Radiological instrument

    International Nuclear Information System (INIS)

    Kronenberg, S.; McLaughlin, W.L.; Seibentritt, C.R. Jr.

    1986-01-01

    An instrument is described for measuring radiation, particularly nuclear radiation, comprising: a radiation sensitive structure pivoted toward one end and including a pair of elongated solid members contiguously joined together along their length dimensions and having a common planar interface therebetween. One of the pairs of members is comprised of radiochromic material whose index of refraction changes due to anomolous dispersion as a result of being exposed to nuclear radiation. The pair of members further has mutually different indices of refraction with the member having the larger index of refraction further being transparent for the passage of light and of energy therethrough; means located toward the other end of the structure for varying the angle of longitudinal elevation of the pair of members; means for generating and projecting a beam of light into one end of the member having the larger index of refraction. The beam of light is projected toward the planar interface where it is reflected out of the other end of the same member as a first output beam; means projecting a portion of the beam of light into one end of the member having the larger index of refraction where it traverses therethrough without reflection and out of the other end of the same member as a second output beam; and means adjacent the structure for receiving the first and second output beams, whereby a calibrated change in the angle of elevation of the structure between positions of equal intensity of the first and second output beams prior to and following exposure provides a measure of the radiation sensed due to a change of refraction of the radiochromic material

  7. The Grism Lens-Amplified Survey from Space (GLASS). VI. Comparing the Mass and Light in MACS J0416.1-2403 Using Frontier Field Imaging and GLASS Spectroscopy

    Science.gov (United States)

    Hoag, A.; Huang, K.-H.; Treu, T.; Bradač, M.; Schmidt, K. B.; Wang, X.; Brammer, G. B.; Broussard, A.; Amorin, R.; Castellano, M.; Fontana, A.; Merlin, E.; Schrabback, T.; Trenti, M.; Vulcani, B.

    2016-11-01

    We present a model using both strong and weak gravitational lensing of the galaxy cluster MACS J0416.1-2403, constrained using spectroscopy from the Grism Lens-Amplified Survey from Space (GLASS) and Hubble Frontier Fields (HFF) imaging data. We search for emission lines in known multiply imaged sources in the GLASS spectra, obtaining secure spectroscopic redshifts of 30 multiple images belonging to 15 distinct source galaxies. The GLASS spectra provide the first spectroscopic measurements for five of the source galaxies. The weak lensing signal is acquired from 884 galaxies in the F606W HFF image. By combining the weak lensing constraints with 15 multiple image systems with spectroscopic redshifts and nine multiple image systems with photometric redshifts, we reconstruct the gravitational potential of the cluster on an adaptive grid. The resulting map of total mass density is compared with a map of stellar mass density obtained from the deep Spitzer Frontier Fields imaging data to study the relative distribution of stellar and total mass in the cluster. We find that the projected stellar mass to total mass ratio, f ⋆, varies considerably with the stellar surface mass density. The mean projected stellar mass to total mass ratio is =0.009+/- 0.003 (stat.), but with a systematic error as large as 0.004-0.005, dominated by the choice of the initial mass function. We find agreement with several recent measurements of f ⋆ in massive cluster environments. The lensing maps of convergence, shear, and magnification are made available to the broader community in the standard HFF format.

  8. Metallicities of Emission-Line Galaxies from HST ACS PEARS and HST WFC3 ERS Grism Spectroscopy at 0.6 is less than z is less than 2.4

    Science.gov (United States)

    Xia, Lifang; Malhotra, Sangetta; Rhoads, James; Pirzkal, Nor; Straughn, Amber; Finkelstein, Steven; Cohen, Seth; Kuntschner, Harald; Walsh, Jeremy; Windhorst, Rogier A.; hide

    2012-01-01

    Galaxies selected on the basis of their emission line strength. show low metallicities, regardless of their redshifts. We conclude this from a sample of faint galaxies at redshifts between 0.6 optiCa.i with the Advanced Camera for Surveys (ACS) on the Hubble Space Telescope (HST) and in the near-infrared using Wide-Field Camera 3 (WFC3). Using a sample of 11 emission line galaxies (ELGs) at 0.6 < z < 2.4 with luminosities of -22 approx < MB approx -19 which have [OII], H-Beta, and [OIII] line flux measurements from the combination of two grism spectral surveys, we use the R23 method to derive the gas-phase oxygen abundances: 7.5 <12+log(0/H)<8.5. The galaxy stellar masses are derived using Bayesian based Markov Chain Monte Carlo (pi MC(exp 2)) fitting of their Spectral Energy Distribution (SED), and span the mass range 8.1 < log(M(stellar)/M(solar)) < 10.1. These galaxies show a mass-metal1icity (M-L) and Luminosity-Metallicity (LZ) relation, which is offset by -

  9. Obtención de anticuerpos policlonales IgY antiparvovirus canino y evaluación en un sistema de aglutinación con látex

    Directory of Open Access Journals (Sweden)

    Jannet González-Figueredo

    2015-12-01

    Full Text Available La parvovirosis canina es una de las principales infecciones que provoca gastroenteritis, fundamentalmente en cachorros, con altos índices de morbiletalidad. Los diagnosticadores más utilizados se basan en la detección de partículas virales excretadas durante la fase aguda de la enfermedad. Algunos requieren equipos especializados, lo que aumenta los costos y el tiempo de diagnóstico. Por esto, la simplificación de estos métodos con alta sensibilidad y especificidad es prioritaria. En Cuba solo se logra un diagnóstico presuntivo sin la completa confirmación de la enfermedad, principalmente por la escasez o ausencia de un medio diagnóstico en toda la red de consultorios y clínicas veterinarias, rápido, eficaz y ajustable a nuestras condiciones. Este trabajo tuvo como objetivo obtener anticuerpos policlonales IgY a partir de yema de huevo de gallina y evaluarlos mediante un sistema de látex-aglutinación, para su posible uso como terapia y principalmente en el diagnóstico. Se inmunizaron por vía intramuscular dos gallinas de raza Leghorn con una cepa atenuada de parvovirus canino (PVC tipo 2. Se aplicaron 8 inoculaciones por ave cada 15 días. Se cosecharon los huevos y se purificaron los anticuerpos por el método de sulfato de dextrana/sulfato de sodio. Se determinó el título de IgY anti-PVC por el método de Inhibición de la Hemoaglutinación (IH y con antígeno de PVC acoplado a partículas de látex de poliestireno. Por IH se obtuvo un título de IgY anti-PVC de 1:1024. Las mezclas de anticuerpos con títulos alto y medio de ambas gallinas aglutinaron con los reactivos preparados con 230 y 460 µg/mL de antígeno. La mayor intensidad de la reacción y la mejor detectabilidad correspondieron a los reactivos elaborados con los anticuerpos de mayor título.

  10. Evaluating musical instruments

    International Nuclear Information System (INIS)

    Campbell, D. Murray

    2014-01-01

    Scientific measurements of sound generation and radiation by musical instruments are surprisingly hard to correlate with the subtle and complex judgments of instrumental quality made by expert musicians

  11. IOT Overview: IR Instruments

    Science.gov (United States)

    Mason, E.

    In this instrument review chapter the calibration plans of ESO IR instruments are presented and briefly reviewed focusing, in particular, on the case of ISAAC, which has been the first IR instrument at VLT and whose calibration plan served as prototype for the coming instruments.

  12. Health physics instrument manual

    International Nuclear Information System (INIS)

    Gupton, E.D.

    1978-08-01

    The purpose of this manual is to provide apprentice health physics surveyors and other operating groups not directly concerned with radiation detection instruments a working knowledge of the radiation detection and measuring instruments in use at the Laboratory. The characteristics and applications of the instruments are given. Portable instruments, stationary instruments, personnel monitoring instruments, sample counters, and miscellaneous instruments are described. Also, information sheets on calibration sources, procedures, and devices are included. Gamma sources, beta sources, alpha sources, neutron sources, special sources, a gamma calibration device for badge dosimeters, and a calibration device for ionization chambers are described

  13. Astronomical Instruments in India

    Science.gov (United States)

    Sarma, Sreeramula Rajeswara

    The earliest astronomical instruments used in India were the gnomon and the water clock. In the early seventh century, Brahmagupta described ten types of instruments, which were adopted by all subsequent writers with minor modifications. Contact with Islamic astronomy in the second millennium AD led to a radical change. Sanskrit texts began to lay emphasis on the importance of observational instruments. Exclusive texts on instruments were composed. Islamic instruments like the astrolabe were adopted and some new types of instruments were developed. Production and use of these traditional instruments continued, along with the cultivation of traditional astronomy, up to the end of the nineteenth century.

  14. Troubleshooting in nuclear instruments

    International Nuclear Information System (INIS)

    1987-06-01

    This report on troubleshooting of nuclear instruments is the product of several scientists and engineers, who are closely associated with nuclear instrumentation and with the IAEA activities in the field. The text covers the following topics: Preamplifiers, amplifiers, scalers, timers, ratemeters, multichannel analyzers, dedicated instruments, tools, instruments, accessories, components, skills, interfaces, power supplies, preventive maintenance, troubleshooting in systems, radiation detectors. The troubleshooting and repair of instruments is illustrated by some real examples

  15. Performing the Super Instrument

    DEFF Research Database (Denmark)

    Kallionpaa, Maria

    2016-01-01

    can empower performers by producing super instrument works that allow the concert instrument to become an ensemble controlled by a single player. The existing instrumental skills of the performer can be multiplied and the qualities of regular acoustic instruments extended or modified. Such a situation......The genre of contemporary classical music has seen significant innovation and research related to new super, hyper, and hybrid instruments, which opens up a vast palette of expressive potential. An increasing number of composers, performers, instrument designers, engineers, and computer programmers...... have become interested in different ways of “supersizing” acoustic instruments in order to open up previously-unheard instrumental sounds. Super instruments vary a great deal but each has a transformative effect on the identity and performance practice of the performing musician. Furthermore, composers...

  16. Instrument Modeling and Synthesis

    Science.gov (United States)

    Horner, Andrew B.; Beauchamp, James W.

    During the 1970s and 1980s, before synthesizers based on direct sampling of musical sounds became popular, replicating musical instruments using frequency modulation (FM) or wavetable synthesis was one of the “holy grails” of music synthesis. Synthesizers such as the Yamaha DX7 allowed users great flexibility in mixing and matching sounds, but were notoriously difficult to coerce into producing sounds like those of a given instrument. Instrument design wizards practiced the mysteries of FM instrument design.

  17. Nuclear reactor instrumentation

    International Nuclear Information System (INIS)

    Duncombe, E.; McGonigal, G.

    1975-01-01

    A liquid metal cooled nuclear reactor is described which has an equal number of fuel sub-assemblies and sensing instruments. Each instrument senses temperature and rate of coolant flow of a coolant derived from a group of three sub-assemblies so that an abnormal value for one sub-assembly will be indicated on three instruments thereby providing for redundancy of up to two of the three instruments. The abnormal value may be a precurser to unstable boiling of coolant

  18. Aeroacoustics of Musical Instruments

    NARCIS (Netherlands)

    Fabre, B.; Gilbert, J.; Hirschberg, Abraham; Pelorson, X.

    2012-01-01

    We are interested in the quality of sound produced by musical instruments and their playability. In wind instruments, a hydrodynamic source of sound is coupled to an acoustic resonator. Linear acoustics can predict the pitch of an instrument. This can significantly reduce the trial-and-error process

  19. Elisa de captura com IgY para quantificação de acetato de lupeol em Vernonia scorpioides lam. Pers (asteraceae Capture IgY-elisa to quantify lupeol acetate in Vernonia scorpioides lam. Pers (asteraceae

    Directory of Open Access Journals (Sweden)

    Ronald Bastos Freire

    2004-08-01

    Full Text Available O presente experimento descreve, pela primeira vez, a elaboração de um ensaio imunoenzimático (ELISA de captura com anticorpos IgY para a detecção e quantificação de acetato de lupeol (LAc em Vernonia scorpioides Lam. Pers (Asteraceae. Anticorpos anti-LAc, obtidos partir do soro das aves e gemas de seus ovos, após imunização com o conjugado acetato de lupeol-cBSA, foram concentrados em coluna contendo LAc-BSA acoplado a sepharose. A eficácia da metodologia de detecção imunológica foi de 97%, com índices de sensibilidade e especificidade de 99% e 95%, respectivamente com limites de detecção do ensaio entre 0,02µg.g-1 (inferior e 10 µg.g-1 (superior. A robustez do método foi atestada pela sua elevada reprodutibilidade (entre 94,75% e 96,81%, e pelo baixo coeficiente de variação interna (4,22 ± 1,03% nas condições de execução descritas.For the first time, a yolk immunoglobulins-based immunenzymatic assay (capture IgY-ELISA was carried out to detect Lupeol acetate (LAc from Vernonia scorpioides Lam. Pers (Asteraceae. Antibodies (IgY against lupeol acetate (anti-LAc antibodies were raised in White Leghorn hens immunized with LAc conjugated to the bovine serum albumin (LAc-BSA. The anti-LAc antibodies were recovered by cleanup columns containing LAc-BSA coupled to sepharose. The capture IgY-ELISA efficacy was of 97% when the predictive indices of sensitivity and specificity were 99.0% and 95%, respectively. The lowest and highest detection limits were of 0.02µg g-1 and 10µg.g-1 of plant extract, respectively. The strength of this method was attested by its high reproducibility (between 94.75% and 96.81%, and a low internal variation (4.22 ± 1.03%, under the described conditions.

  20. Status of safeguards instrumentation

    International Nuclear Information System (INIS)

    Higinbotham, W.A.

    The International Atomic Energy Agency is performing safeguards at some nuclear power reactors, 50 bulk processing facilities, and 170 research facilities. Its verification activities require the use of instruments to measure nuclear materials and of surveillance instruments to maintain continuity of knowledge of the locations of nuclear materials. Instruments that are in use and under development to measure weight, volume, concentration, and isotopic composition of nuclear materials, and the major surveillance instruments, are described in connection with their uses at representative nuclear facilities. The current status of safeguards instrumentation and the needs for future development are discussed

  1. Early modern mathematical instruments.

    Science.gov (United States)

    Bennett, Jim

    2011-12-01

    In considering the appropriate use of the terms "science" and "scientific instrument," tracing the history of "mathematical instruments" in the early modern period is offered as an illuminating alternative to the historian's natural instinct to follow the guiding lights of originality and innovation, even if the trail transgresses contemporary boundaries. The mathematical instrument was a well-defined category, shared across the academic, artisanal, and commercial aspects of instrumentation, and its narrative from the sixteenth to the eighteenth century was largely independent from other classes of device, in a period when a "scientific" instrument was unheard of.

  2. Feeding different levels of vitamin E and selenium has no effect on serum immunoglobulin Y (IgY production by layers vaccinated against Escherichia coli and avian encephalomyelitis virus Alimentação com diferentes níveis de vitamina E e selênio não influencia a produção de imunoglobulina Y (IgY no soro de poedeiras leves vacinadas contra Escherichia coli e encefalomielite aviária

    Directory of Open Access Journals (Sweden)

    Giselle Kindlein

    2007-10-01

    Full Text Available The effects of vitamin E and selenium (Se supplementation on the immunity of hens vaccinated against a mixture of six swine-pathogenic Escherichia coli (EC and avian encephalomyelitis virus (AEV were studied. Antibody production (AbP was evaluated in ninety 49 to 57-week-old H&N Nick Chick hens fed diets containing 14IU Vitamin E kg-1 (basal diet, 27, 59, 111, or 111IU vitamin E kg-1 + 0.56ppm Se supplementation. At 51 wks of age, half of the hens were vaccinated against EC, and all birds were vaccinated against AEV. At 53-weeks of age, the birds received a second dose of EC vaccine. Blood samples were collected weekly and serum was analyzed by ELISA for anti-EC IgY and was expressed as optical density (OD. Vaccinated hens had higher serum OD than the non-vaccinated hens (P£0.05. Vaccinated hens fed 27 and 59IU of vitamin E/kg had a higher (POs efeitos da suplementação de vitamina E e Selênio (Se na imunidade de galinhas vacinadas contra uma mistura de 6 sorotipos patogênicos de Escherichia coli (EC e o vírus da encefalomielite aviária (VEA foram estudados. A produção de anticorpos foi avaliada em galinhas H&N Nick Chick durante a 49a e 57a semanas de vida. As aves foram alimentadas com dietas contendo 14UI de Vitamina E kg-1 (dieta basal, 27, 59, 111 e 111UI de Vitamina E kg-1 + 0,56ppm Se suplementar. Às 51 semanas de idade, metade das galinhas foi vacinada contra EC, e todas as aves foram vacinadas contra VEA. Às 53 semanas, as aves receberam a segunda vacina contra EC. Amostras de sangue foram coletadas semanalmente e o soro foi analisado por ELISA para anti-EC IgY e expresso como densidade óptica (DO. Galinhas vacinadas tiveram maior DO do que as não-vacinadas (P<0,05. Aves vacinadas que receberam 27 e 59 UI de vitamina E/kg tiveram maior DO do soro (P<0,05 do que as alimentadas com 111 UI + Se. Os antígenos utilizados mostraram não ser modelos satisfatórios para estudar a influência de micronutrientes na resposta imune de

  3. Evaluation of Chicken IgY Generated Against Canine Parvovirus Viral-Like Particles and Development of Enzyme-Linked Immunosorbent Assay and Immunochromatographic Assay for Canine Parvovirus Detection.

    Science.gov (United States)

    He, Jinxin; Wang, Yuan; Sun, Shiqi; Zhang, Xiaoying

    2015-11-01

    Immunoglobulin Y (IgY) antibodies were generated against canine parvovirus virus-like particles (CPV-VLPs) antigen using chickens. Anti-CPV-VLPs-IgY was extracted from hen egg yolk and used for developing enzyme-linked immunosorbent assay (ELISA) and immunochromatographic assay (ICA) for the detection of CPV in dog feces. The cutoff negative values for anti-CPV-VLPs-IgY were determined using negative fecal samples (already confirmed by polymerase chain reaction [PCR]). In both ELISA and ICA, there was no cross-reaction with other diarrheal pathogens. Thirty-four fecal samples were collected from dogs with diarrhea, of which 26.47% were confirmed as CPV-positive samples by PCR, while 29.41% and 32.35% of the samples were found to be positive by ELISA and ICA, respectively. The developed ELISA and ICA exhibited 97.06% and 94.12% conformity with PCR. Higher sensitivity and specificity were observed for IgY-based ELISA and ICA. Thus, they could be suitable for routine use in the diagnosis of CPV in dogs.

  4. Instrumentation a reader

    CERN Document Server

    Pope, P

    1990-01-01

    This book contains a selection of papers and articles in instrumentation previously pub­ lished in technical periodicals and journals of learned societies. Our selection has been made to illustrate aspects of current practice and applications of instrumentation. The book does not attempt to be encyclopaedic in its coverage of the subject, but to provide some examples of general transduction techniques, of the sensing of particular measurands, of components of instrumentation systems and of instrumentation practice in two very different environments, the food industry and the nuclear power industry. We have made the selection particularly to provide papers appropriate to the study of the Open University course T292 Instrumentation. The papers have been chosen so that the book covers a wide spectrum of instrumentation techniques. Because of this, the book should be of value not only to students of instrumen­ tation, but also to practising engineers and scientists wishing to glean ideas from areas of instrumen...

  5. Instrumentation for Nuclear Applications

    International Nuclear Information System (INIS)

    1998-01-01

    The objective of this project was to develop and coordinate nuclear instrumentation standards with resulting economies for the nuclear and radiation fields. There was particular emphasis on coordination and management of the Nuclear Instrument Module (NIM) System, U.S. activity involving the CAMAC international standard dataway system, the FASTBUS modular high-speed data acquisition and control system and processing and management of national nuclear instrumentation and detector standards, as well as a modest amount of assistance and consultation services to the Pollutant Characterization and Safety Research Division of the Office of Health and Environmental Research. The principal accomplishments were the development and maintenance of the NIM instrumentation system that is the predominant instrumentation system in the nuclear and radiation fields worldwide, the CAMAC digital interface system in coordination with the ESONE Committee of European Laboratories, the FASTBUS high-speed system and numerous national and international nuclear instrumentation standards

  6. VIRUS instrument enclosures

    Science.gov (United States)

    Prochaska, T.; Allen, R.; Mondrik, N.; Rheault, J. P.; Sauseda, M.; Boster, E.; James, M.; Rodriguez-Patino, M.; Torres, G.; Ham, J.; Cook, E.; Baker, D.; DePoy, Darren L.; Marshall, Jennifer L.; Hill, G. J.; Perry, D.; Savage, R. D.; Good, J. M.; Vattiat, Brian L.

    2014-08-01

    The Visible Integral-Field Replicable Unit Spectrograph (VIRUS) instrument will be installed at the Hobby-Eberly Telescope† in the near future. The instrument will be housed in two enclosures that are mounted adjacent to the telescope, via the VIRUS Support Structure (VSS). We have designed the enclosures to support and protect the instrument, to enable servicing of the instrument, and to cool the instrument appropriately while not adversely affecting the dome environment. The system uses simple HVAC air handling techniques in conjunction with thermoelectric and standard glycol heat exchangers to provide efficient heat removal. The enclosures also provide power and data transfer to and from each VIRUS unit, liquid nitrogen cooling to the detectors, and environmental monitoring of the instrument and dome environments. In this paper, we describe the design and fabrication of the VIRUS enclosures and their subsystems.

  7. Radiation protection instrument 1993

    International Nuclear Information System (INIS)

    1993-04-01

    The Radiation Protection Instrument, 1993 (Legislative Instrument 1559) prescribes the powers and functions of the Radiation Protection Board established under the Ghana Atomic Energy Commission by the Atomic Energy Commission (Amendment) Law, 1993 (P.N.D.C. Law 308). Also included in the Legislative Instrument are schedules on control and use of ionising radiation and radiation sources as well as procedures for notification, licensing and inspection of ionising radiation facilities. (EAA)

  8. Networked Instrumentation Element

    Data.gov (United States)

    National Aeronautics and Space Administration — Armstrong researchers have developed a networked instrumentation system that connects modern experimental payloads to existing analog and digital communications...

  9. Instrument validation project

    International Nuclear Information System (INIS)

    Reynolds, B.A.; Daymo, E.A.; Geeting, J.G.H.; Zhang, J.

    1996-06-01

    Westinghouse Hanford Company Project W-211 is responsible for providing the system capabilities to remove radioactive waste from ten double-shell tanks used to store radioactive wastes on the Hanford Site in Richland, Washington. The project is also responsible for measuring tank waste slurry properties prior to injection into pipeline systems, including the Replacement of Cross-Site Transfer System. This report summarizes studies of the appropriateness of the instrumentation specified for use in Project W-211. The instruments were evaluated in a test loop with simulated slurries that covered the range of properties specified in the functional design criteria. The results of the study indicate that the compact nature of the baseline Project W-211 loop does not result in reduced instrumental accuracy resulting from poor flow profile development. Of the baseline instrumentation, the Micromotion densimeter, the Moore Industries thermocouple, the Fischer and Porter magnetic flow meter, and the Red Valve Pressure transducer meet the desired instrumental accuracy. An alternate magnetic flow meter (Yokagawa) gave nearly identical results as the baseline fischer and Porter. The Micromotion flow meter did not meet the desired instrument accuracy but could potentially be calibrated so that it would meet the criteria. The Nametre on-line viscometer did not meet the desired instrumental accuracy and is not recommended as a quantitative instrument although it does provide qualitative information. The recommended minimum set of instrumentation necessary to ensure the slurry meets the Project W-058 acceptance criteria is the Micromotion mass flow meter and delta pressure cells

  10. Instrument performance evaluation

    International Nuclear Information System (INIS)

    Swinth, K.L.

    1993-03-01

    Deficiencies exist in both the performance and the quality of health physics instruments. Recognizing the implications of such deficiencies for the protection of workers and the public, in the early 1980s the DOE and the NRC encouraged the development of a performance standard and established a program to test a series of instruments against criteria in the standard. The purpose of the testing was to establish the practicality of the criteria in the standard, to determine the performance of a cross section of available instruments, and to establish a testing capability. Over 100 instruments were tested, resulting in a practical standard and an understanding of the deficiencies in available instruments. In parallel with the instrument testing, a value-impact study clearly established the benefits of implementing a formal testing program. An ad hoc committee also met several times to establish recommendations for the voluntary implementation of a testing program based on the studies and the performance standard. For several reasons, a formal program did not materialize. Ongoing tests and studies have supported the development of specific instruments and have helped specific clients understand the performance of their instruments. The purpose of this presentation is to trace the history of instrument testing to date and suggest the benefits of a centralized formal program

  11. [Controlling instruments in radiology].

    Science.gov (United States)

    Maurer, M

    2013-10-01

    Due to the rising costs and competitive pressures radiological clinics and practices are now facing, controlling instruments are gaining importance in the optimization of structures and processes of the various diagnostic examinations and interventional procedures. It will be shown how the use of selected controlling instruments can secure and improve the performance of radiological facilities. A definition of the concept of controlling will be provided. It will be shown which controlling instruments can be applied in radiological departments and practices. As an example, two of the controlling instruments, material cost analysis and benchmarking, will be illustrated.

  12. Ocean Optics Instrumentation Systems

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides instrumentation suites for a wide variety of measurements to characterize the ocean’s optical environment. These packages have been developed to...

  13. The CU 2-D-MAX-DOAS instrument – Part 2: Raman scattering probability measurements and retrieval of aerosol optical properties

    Energy Technology Data Exchange (ETDEWEB)

    Ortega, Ivan; Coburn, Sean; Berg, Larry K.; Lantz, Kathy; Michalsky, Joseph; Ferrare, Richard A.; Hair, Johnathan W.; Hostetler, Chris A.; Volkamer, Rainer

    2016-01-01

    The multiannual global mean of aerosol optical depth at 550 nm (AOD550) over land is ~0.19, and that over oceans is ~0.13. About 45 % of the Earth surface shows AOD550 smaller than 0.1. There is a need for measurement techniques that are optimized to measure aerosol optical properties under low AOD conditions. We present an inherently calibrated retrieval (i.e., no need for radiance calibration) to simultaneously measure AOD and the aerosol phase function parameter, <i>g>, based on measurements of azimuth distributions of the Raman scattering probability (RSP), the near-absolute rotational Raman scattering (RRS) intensity. We employ radiative transfer model simulations to show that for solar azimuth RSP measurements at solar elevation and solar zenith angle (SZA) smaller than 80°, RSP is insensitive to the vertical distribution of aerosols and maximally sensitive to changes in AOD and <i>g> under near-molecular scattering conditions. The University of Colorado two-dimensional Multi-AXis Differential Optical Absorption Spectroscopy (CU 2-D-MAX-DOAS) instrument was deployed as part of the Two Column Aerosol Project (TCAP) at Cape Cod, MA, during the summer of 2012 to measure direct sun spectra and RSP from scattered light spectra at solar relative azimuth angles (SRAAs) between 5 and 170°. During two case study days with (1) high aerosol load (17 July, 0.3 < AOD430 < 0.6) and (2) near-molecular scattering conditions (22 July, AOD430 < 0.13) we compare RSP-based retrievals of AOD430 and <i>g> with data from a co-located CIMEL sun photometer, Multi-Filter Rotating Shadowband Radiometer (MFRSR), and an airborne High Spectral Resolution Lidar (HSRL-2). The average difference (relative to DOAS) for AOD430 is +0.012 ± 0.023 (CIMEL), -0.012 ± 0.024 (MFRSR), -0.011 ± 0.014 (HSRL-2), and +0.023 ± 0.013 (CIMELAOD - MFRSRAOD) and yields the following

  14. Overview of LOFT instrumentation

    International Nuclear Information System (INIS)

    Bixby, W.W.

    1979-01-01

    A description of instrumentation used in the Loss-of-Fluid Test (LOFT) large break Loss-of-Coolant Experiments is presented. Emphasis is placed on hydraulic and thermal measurements in the primary system piping and components, reactor vessel, and pressure suppression system. In addition, instrumentation which is being considered for measurement of phenomena during future small break testing is discussed

  15. Instrumentation reference book

    CERN Document Server

    Boyes, Walt

    2002-01-01

    Instrumentation is not a clearly defined subject, having a 'fuzzy' boundary with a number of other disciplines. Often categorized as either 'techniques' or 'applications' this book addresses the various applications that may be needed with reference to the practical techniques that are available for the instrumentation or measurement of a specific physical quantity or quality. This makes it of direct interest to anyone working in the process, control and instrumentation fields where these measurements are essential.* Comprehensive and authoritative collection of technical information* Writte

  16. The latest radiation instrument

    International Nuclear Information System (INIS)

    Kang, Se Sik; Gwon, Dal Gwan; Kim, Gyeong Geum

    2008-08-01

    This book deals with the latest radiation instrument, which is comprised of eight chapters. It explains X rays instrument for medial treatment, X-ray tube instrument and permissible burden with its history, structure and characteristic high voltage apparatus with high voltage rectifier circuit, X-ray control apparatus for medical treatment, X-ray image equipment X-ray television apparatus and CCD 205, X-ray apparatus of install and types, Digital X-ray apparatus with CR 261 and DR 269, performance management on X-ray for medical treatment with its history, necessity and management in the radiation field.

  17. Soil monitoring instrumentation

    International Nuclear Information System (INIS)

    Umbarger, C.J.

    1980-01-01

    The Los Alamos Scientific Laboratory (LASL) has an extensive program for the development of nondestructive assay instrumentation for the quantitative analysis of transuranic (TRU) materials found in bulk solid wastes generated by Department of Energy facilities and by the commercial nuclear power industry. Included are wastes generated in decontamination and decommissioning of outdated nuclear facilities as well as wastes from old waste burial ground exhumation programs. The assay instrumentation is designed to have detection limits below 10 nCi/g wherever practicable. Because of the topic of this workshop, only the assay instrumentation applied specifically to soil monitoring will be discussed here. Four types of soil monitors are described

  18. Soil monitoring instrumentation

    International Nuclear Information System (INIS)

    Umbarger, C.J.

    1981-01-01

    The Los Alamos Scientific Laboratory (LASL) has an extensive program for the development of nondestructive assay instrumentation for the quantitative analysis of transuranic (TRU) materials found in bulk solid wastes generated by Department of Energy facilities and by the commercial nuclear power industry. Included are wastes generated in decontamination and decommissioning of outdated nuclear facilities, as well as from old waste-burial-ground exhumation programs. The assay instrumentation is designed to have detection limits below 10 nCi/g wherever practicable. The assay instrumentation that is applied specifically to soil monitoring is discussed

  19. Jones' instrument technology

    CERN Document Server

    Jones, Ernest Beachcroft; Kingham, Edward G; Radnai, Rudolf

    1985-01-01

    Jones' Instrument Technology, Volume 5: Automatic Instruments and Measuring Systems deals with general trends in automatic instruments and measuring systems. Specific examples are provided to illustrate the principles of such devices. A brief review of a considerable number of standards is undertaken, with emphasis on the IEC625 Interface System. Other relevant standards are reviewed, including the interface and backplane bus standards. This volume is comprised of seven chapters and begins with a short introduction to the principles of automatic measurements, classification of measuring system

  20. Medical instruments in museums

    DEFF Research Database (Denmark)

    Söderqvist, Thomas; Arnold, Ken

    2011-01-01

    This essay proposes that our understanding of medical instruments might benefit from adding a more forthright concern with their immediate presence to the current historical focus on simply decoding their meanings and context. This approach is applied to the intriguingly tricky question of what...... actually is meant by a "medical instrument." It is suggested that a pragmatic part of the answer might lie simply in reconsidering the holdings of medical museums, where the significance of the physical actuality of instruments comes readily to hand....

  1. Environment for the instruments

    International Nuclear Information System (INIS)

    Ambro, P.

    1992-01-01

    A properly conditioned AC power supply is necessary for reliable functioning of instruments. Electric mains power is produced primarily for industry, workshops, lighting and household uses. Its quality is adjusted to these uses. In areas sand countries with a fast growing demand for electric power, these requirements are far from being met. Electronic instruments and computers, especially in these countries, need protection against disturbances of the mains supply. A clean and dry environment is needed for reliable functioning and long life of instruments. High humidity, specially at higher temperatures, changes the characteristics of electronic components. Moreover, under these conditions fungal growth causes leakage of currents and corrosion causes poor contacts. The presence of dust enhances these effects. They give rise to malfunction of instruments, particularly of high voltage equipment

  2. CCAT Heterodyne Instrument Development

    Data.gov (United States)

    National Aeronautics and Space Administration — This work will extend and proof-out the design concept for a high pixel count (128 pixels in 2 bands) submillimeter-wave heterodyne receiver array instrument for the...

  3. Environment for the instruments

    Energy Technology Data Exchange (ETDEWEB)

    Ambro, P

    1993-12-31

    A properly conditioned AC power supply is necessary for reliable functioning of instruments. Electric mains power is produced primarily for industry, workshops, lighting and household uses. Its quality is adjusted to these uses. In areas sand countries with a fast growing demand for electric power, these requirements are far from being met. Electronic instruments and computers, especially in these countries, need protection against disturbances of the mains supply. A clean and dry environment is needed for reliable functioning and long life of instruments. High humidity, specially at higher temperatures, changes the characteristics of electronic components. Moreover, under these conditions fungal growth causes leakage of currents and corrosion causes poor contacts. The presence of dust enhances these effects. They give rise to malfunction of instruments, particularly of high voltage equipment

  4. Fiber Optics Instrumentation Development

    Science.gov (United States)

    Chan, Patrick Hon Man; Parker, Allen R., Jr.; Richards, W. Lance

    2010-01-01

    This is a general presentation of fiber optics instrumentation development work being conducted at NASA Dryden for the past 10 years and recent achievements in the field of fiber optics strain sensors.

  5. Nuclear instrument technician training

    International Nuclear Information System (INIS)

    Wollesen, E.S.

    1991-01-01

    This paper reports on Nuclear Instrument Technician (NIT) training that has developed at an accelerated rate over the past three decades. During the 1960's commercial nuclear power plants were in their infancy. For that reason, there is little wonder that NIT training had little structure and little creditability. NIT training, in many early plants, was little more than On-The Job Training (OJT). The seventies brought changes in Instrumentation and Controls as well as emphasis on the requirements for more in depth training and documentation. As in the seventies, the eighties saw not only changes in technologies but tighter requirements, standardized training and the development of accredited Nuclear Instrument Training; thus the conclusion: Nuclear Instrument Training Isn't What It Used To Be

  6. Carbon Footprint Reduction Instruments

    Science.gov (United States)

    This page outlines the major differences between Renewable Energy Certificates (REC) and Project Offsets and what types of claims each instrument allows the organization to make in regards to environmental emissions claims.

  7. Instrument care: everyone's responsibility

    Directory of Open Access Journals (Sweden)

    Renée du Toit

    2011-12-01

    Full Text Available Everyone working in an ophthalmic operating theatre must be competent in the care, handling, storage, and maintenance of instruments. This will help to improve surgical outcomes, maintain an economic and affordable service for patients, and provide a safe environment for the wellbeing of patients and staff.Including instrument care in theatre courses and in-service training is one way of ensuring staff competence.

  8. Instrument uncertainty predictions

    International Nuclear Information System (INIS)

    Coutts, D.A.

    1991-07-01

    The accuracy of measurements and correlations should normally be provided for most experimental activities. The uncertainty is a measure of the accuracy of a stated value or equation. The uncertainty term reflects a combination of instrument errors, modeling limitations, and phenomena understanding deficiencies. This report provides several methodologies to estimate an instrument's uncertainty when used in experimental work. Methods are shown to predict both the pretest and post-test uncertainty

  9. Experimenting with woodwind instruments

    Science.gov (United States)

    Lo Presto, Michael C.

    2007-05-01

    Simple experiments involving musical instruments of the woodwind family can be used to demonstrate the basic physics of vibrating air columns in resonance tubes using nothing more than straightforward measurements and data collection hardware and software. More involved experimentation with the same equipment can provide insight into the effects of holes in the tubing and other factors that make simple tubes useful as musical instruments.

  10. Maintenance of scientific instruments

    International Nuclear Information System (INIS)

    Lucero, E.

    1986-01-01

    During the last years Colombia has increased the use of nuclear techniques, instruments and equipment in ambitious health programs, as well as in research centers, industry and education; this has resulted in numerous maintenance problems. As an alternative solution IAN has established a Central Maintenance Laboratory for nuclear instruments within an International Atomic Energy Agency program for eight Latin American and nine Asian Countries. Established strategies and some results are detailed in this writing

  11. Advanced optical instruments technology

    Science.gov (United States)

    Shao, Mike; Chrisp, Michael; Cheng, Li-Jen; Eng, Sverre; Glavich, Thomas; Goad, Larry; Jones, Bill; Kaarat, Philip; Nein, Max; Robinson, William

    1992-08-01

    The science objectives for proposed NASA missions for the next decades push the state of the art in sensitivity and spatial resolution over a wide range of wavelengths, including the x-ray to the submillimeter. While some of the proposed missions are larger and more sensitive versions of familiar concepts, such as the next generation space telescope, others use concepts, common on the Earth, but new to space, such as optical interferometry, in order to provide spatial resolutions impossible with other concepts. However, despite their architecture, the performance of all of the proposed missions depends critically on the back-end instruments that process the collected energy to produce scientifically interesting outputs. The Advanced Optical Instruments Technology panel was chartered with defining technology development plans that would best improve optical instrument performance for future astrophysics missions. At this workshop the optical instrument was defined as the set of optical components that reimage the light from the telescope onto the detectors to provide information about the spatial, spectral, and polarization properties of the light. This definition was used to distinguish the optical instrument technology issues from those associated with the telescope, which were covered by a separate panel. The panel identified several areas for optical component technology development: diffraction gratings; tunable filters; interferometric beam combiners; optical materials; and fiber optics. The panel also determined that stray light suppression instruments, such as coronagraphs and nulling interferometers, were in need of general development to support future astrophysics needs.

  12. Problems with radiological surveillance instrumentation

    International Nuclear Information System (INIS)

    Swinth, K.L.; Tanner, J.E.; Fleming, D.M.

    1984-09-01

    Many radiological surveillance instruments are in use at DOE facilities throughout the country. These instruments are an essential part of all health physics programs, and poor instrument performance can increase program costs or compromise program effectiveness. Generic data from simple tests on newly purchased instruments shows that many instruments will not meet requirements due to manufacturing defects. In other cases, lack of consideration of instrument use has resulted in poor acceptance of instruments and poor reliability. The performance of instruments is highly variable for electronic and mechanical performance, radiation response, susceptibility to interferences and response to environmental factors. Poor instrument performance in these areas can lead to errors or poor accuracy in measurements

  13. Problems with radiological surveillance instrumentation

    International Nuclear Information System (INIS)

    Swinth, K.L.; Tanner, J.E.; Fleming, D.M.

    1985-01-01

    Many radiological surveillance instruments are in use at DOE facilities throughout the country. These instruments are an essential part of all health physics programs, and poor instrument performance can increase program costs or compromise program effectiveness. Generic data from simple tests on newly purchased instruments shows that many instruments will not meet requirements due to manufacturing defects. In other cases, lack of consideration of instrument use has resulted in poor acceptance of instruments and poor reliability. The performance of instruments is highly variable for electronic and mechanical performance, radiation response, susceptibility to interferences and response to environmental factors. Poor instrument performance in these areas can lead to errors or poor accuracy in measurements

  14. Some emergency instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Burgess, P H

    1986-10-01

    The widespread release of activity and the resultant spread of contamination after the Chernobyl accident resulted in requests to NRPB to provide instruments for, and expertise in, the measurement of radiation. The most common request was for advice on the usefulness of existing instruments, but Board staff were also involved in their adaptation or in the development of new instruments specially to meet the circumstances of the accident. The accident occurred on 26 April. On 1 May, NRPB was involved at Heathrow Airport in the monitoring of the British students who had returned from Kiev and Minsk. The main purpose was to reassure the students by checking that their persons and belongings did not have significant surface contamination. Additional measurements were also made of iodine activity in thyroid using hand-held detectors or a mobile body monitor. This operation was arranged with the Foreign and Commonwealth Office, which had also received numerous requests for instruments from embassies and consulates in countries close to the scene of the accident. There was concern for the well-being of staff and other United Kingdom nationals who resided in or intended to visit the most affected countries. The board supplied suitable instruments, and the FCO distributed them to embassies. The frequency of environmental monitoring was increased from 29 April in anticipation of contamination and appropriate Board instrumentation was deployed. After the Chernobyl cloud arrived in the UK on 2 May, there were numerous requests from local government, public authorities, private companies and members of the public for information and advice on monitoring equipment and procedures. Some of these requirements could be met with existing equipment but members of the public were usually advised not to proceed. At a later stage, the contamination of foodstuffs and livestock required the development of an instrument capable of detecting low levels of {sup 137}Cs and {sup 134}Cs in food

  15. Reactor instrumentation and control

    International Nuclear Information System (INIS)

    Wach, D.; Beraha, D.

    1980-01-01

    The methods for measuring radiation are shortly reviewed. The instrumentation for neutron flux measurement is classified into out-of-core and in-core instrumentation. The out-of-core instrumentation monitors the operational range from the subcritical reactor to full power. This large range is covered by several measurement channels which derive their signals from counter tubes and ionization chambers. The in-core instrumentation provides more detailed information on the power distribution in the core. The self-powered neutron detectors and the aeroball system in PWR reactors are discussed. Temperature and pressure measurement devices are briefly discussed. The different methods for leak detection are described. In concluding the plant instrumentation part some new monitoring systems and analysis methods are presented: early failure detection methods by noise analysis, acoustic monitoring and vibration monitoring. The presentation of the control starts from an qualitative assessment of the reactor dynamics. The chosen control strategy leads to the definition of the part-load diagram, which provides the set-points for the different control systems. The tasks and the functions of these control systems are described. In additiion to the control, a number of limiting systems is employed to keep the reactor in a safe operating region. Finally, an outlook is given on future developments in control, concerning mainly the increased application of process computers. (orig./RW)

  16. Instrumental analysis, second edition

    International Nuclear Information System (INIS)

    Christian, G.D.; O'Reilly, J.E.

    1988-01-01

    The second edition of Instrumental Analysis is a survey of the major instrument-based methods of chemical analysis. It appears to be aimed at undergraduates but would be equally useful in a graduate course. The volume explores all of the classical quantitative methods and contains sections on techniques that usually are not included in a semester course in instrumentation (such as electron spectroscopy and the kinetic methods). Adequate coverage of all of the methods contained in this book would require several semesters of focused study. The 25 chapters were written by different authors, yet the style throughout the book is more uniform than in the earlier edition. With the exception of a two-chapter course in analog and digital circuits, the book purports to de-emphasize instrumentation, focusing more on the theory behind the methods and the application of the methods to analytical problems. However, a detailed analysis of the instruments used in each method is by no means absent. The book has the favor of a user's guide to analysis

  17. Biochemistry Instrumentation Core Technology Center

    Data.gov (United States)

    Federal Laboratory Consortium — The UCLA-DOE Biochemistry Instrumentation Core Facility provides the UCLA biochemistry community with easy access to sophisticated instrumentation for a wide variety...

  18. Heat Flux Instrumentation Laboratory (HFIL)

    Data.gov (United States)

    Federal Laboratory Consortium — Description: The Heat Flux Instrumentation Laboratory is used to develop advanced, flexible, thin film gauge instrumentation for the Air Force Research Laboratory....

  19. Characteristics of protective instrumentation

    International Nuclear Information System (INIS)

    Reichart, G.

    1982-01-01

    Protective Instrumentation (PI) for Nuclear Power Plants (NPP) is a general term for an highly reliable instrumentation, which provides information for keeping the system within safe limits, for initation of countermeasures in the case of an incident or for mitigation of consequences of an accident. In German NPPs one can find a hierarchical structure of protective instrumentation, wherein the Reactor Protection System (RPS) has the highest priority. To meet the reliability requirements different design principles are used, like - redundancy - diversity - fail safe - decoupling. The presentation gives an overview about the different design principles and characterizes their reliability aspects. As an example for the technical realization the RPS of a German NPP is discussed in some detail. Furthermore some information about other type of PI is given and reliability aspects of the interaction of operating personell with these systems are mentioned. (orig.)

  20. Aethalometer™ Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Sedlacek, Arthur J. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2016-04-01

    The Aethalometer is an instrument that provides a real-time readout of the concentration of “Black” or “Elemental” carbon aerosol particles (BC or E) in an air stream (see Figure 1 and Figure 2). It is a self-contained instrument that measures the rate of change of optical transmission through a spot on a filter where aerosol is being continuously collected and uses the information to calculate the concentration of optically absorbing material in the sampled air stream. The instrument measures the transmitted light intensities through the “sensing” portion of the filter, on which the aerosol spot is being collected, and a “reference” portion of the filter as a check on the stability of the optical source. A mass flowmeter monitors the sample air flow rate. The data from these three measurements is used to determine the mean BC content of the air stream.

  1. The IKARUS instrument

    International Nuclear Information System (INIS)

    Gerster, H.J.; Stein, G.

    1994-01-01

    When the Federal Government decided on a 25% reduction of CO 2 emissions till 2005 in 1990 the necessity resulted that an instrument has to be developed for the analysis and assessment of the ecological, economic and energetic impact of different reduction strategies. The development task was awarded by the BMFT to the Research Centre Juelich in cooperation with well-known institutions of energy system research. The total instrument is scheduled to be finished by the end of 1994. For the decentral use of the instrument by a wide specialist public the developed models and data banks which are equipped with a user-friendly surface are suited for larger PCs (486, 16 MB RAM/500-1000 MB ROM). (orig.) [de

  2. ISSUERS OF FINANCIAL INSTRUMENTS

    Directory of Open Access Journals (Sweden)

    Cristian GHEORGHE

    2016-05-01

    Full Text Available The rules laid down by Romanian Capital Market Law and the regulations put in force for its implementation apply to issuers of financial instruments admitted to trading on the regulated market established in Romania. But the issuers remain companies incorporated under Company Law of 1990. Such dual regulations need increased attention in order to observe the legal status of the issuers/companies and financial instruments/shares. Romanian legislator has chosen to implement in Capital Market Law special rules regarding the administration of the issuers of financial instruments, not only rules regarding admitting and maintaining to a regulated market. Thus issuers are, in Romanian Law perspective, special company that should comply special rule regarding board of administration and general shareholders meeting.

  3. Microscale depletion of high abundance proteins in human biofluids using IgY14 immunoaffinity resin: analysis of human plasma and cerebrospinal fluid.

    Science.gov (United States)

    Hyung, Seok-Won; Piehowski, Paul D; Moore, Ronald J; Orton, Daniel J; Schepmoes, Athena A; Clauss, Therese R; Chu, Rosalie K; Fillmore, Thomas L; Brewer, Heather; Liu, Tao; Zhao, Rui; Smith, Richard D

    2014-11-01

    Removal of highly abundant proteins in plasma is often carried out using immunoaffinity depletion to extend the dynamic range of measurements to lower abundance species. While commercial depletion columns are available for this purpose, they generally are not applicable to limited sample quantities (depletion media can be prohibitive for larger-scale studies. Modern LC-MS instrumentation provides the sensitivity necessary to scale-down depletion methods with minimal sacrifice to proteome coverage, which makes smaller volume depletion columns desirable for maximizing sample recovery when samples are limited, as well as for reducing the expense of large-scale studies. We characterized the performance of a 346 μL column volume microscale depletion system, using four different flow rates to determine the most effective depletion conditions for ∼6-μL injections of human plasma proteins and then evaluated depletion reproducibility at the optimum flow rate condition. Depletion of plasma using a commercial 10-mL depletion column served as the control. Results showed depletion efficiency of the microscale column increased as flow rate decreased, and that our microdepletion was reproducible. In an initial application, a 600-μL sample of human cerebrospinal fluid (CSF) pooled from multiple sclerosis patients was depleted and then analyzed using reversed phase liquid chromatography-mass spectrometry to demonstrate the utility of the system for this important biofluid where sample quantities are more commonly limited.

  4. Virtual Sensor Test Instrumentation

    Science.gov (United States)

    Wang, Roy

    2011-01-01

    Virtual Sensor Test Instrumentation is based on the concept of smart sensor technology for testing with intelligence needed to perform sell-diagnosis of health, and to participate in a hierarchy of health determination at sensor, process, and system levels. A virtual sensor test instrumentation consists of five elements: (1) a common sensor interface, (2) microprocessor, (3) wireless interface, (4) signal conditioning and ADC/DAC (analog-to-digital conversion/ digital-to-analog conversion), and (5) onboard EEPROM (electrically erasable programmable read-only memory) for metadata storage and executable software to create powerful, scalable, reconfigurable, and reliable embedded and distributed test instruments. In order to maximize the efficient data conversion through the smart sensor node, plug-and-play functionality is required to interface with traditional sensors to enhance their identity and capabilities for data processing and communications. Virtual sensor test instrumentation can be accessible wirelessly via a Network Capable Application Processor (NCAP) or a Smart Transducer Interlace Module (STIM) that may be managed under real-time rule engines for mission-critical applications. The transducer senses the physical quantity being measured and converts it into an electrical signal. The signal is fed to an A/D converter, and is ready for use by the processor to execute functional transformation based on the sensor characteristics stored in a Transducer Electronic Data Sheet (TEDS). Virtual sensor test instrumentation is built upon an open-system architecture with standardized protocol modules/stacks to interface with industry standards and commonly used software. One major benefit for deploying the virtual sensor test instrumentation is the ability, through a plug-and-play common interface, to convert raw sensor data in either analog or digital form, to an IEEE 1451 standard-based smart sensor, which has instructions to program sensors for a wide variety of

  5. ICFA: Instrumentation school

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1987-10-15

    74 students, including 45 from developing countries, ten lecturers and nine laboratory instructors participated in the novel instrumentation school held in June at the International Centre for Theoretical Physics (ICTP), Trieste, Italy, sponsored by ICTP and arranged through the Instrumentation Panel of the International Committee for Future Accelerators (ICF). During the two weeks of the course, students had the chance to construct and test a proportional chamber, measure the lifetime of cosmic ray muons, operate and analyse the performance of an 8-wire imaging drift chamber, or study noise and signal processing using a silicon photodiode.

  6. Interfacing to accelerator instrumentation

    International Nuclear Information System (INIS)

    Shea, T.J.

    1995-01-01

    As the sensory system for an accelerator, the beam instrumentation provides a tremendous amount of diagnostic information. Access to this information can vary from periodic spot checks by operators to high bandwidth data acquisition during studies. In this paper, example applications will illustrate the requirements on interfaces between the control system and the instrumentation hardware. A survey of the major accelerator facilities will identify the most popular interface standards. The impact of developments such as isochronous protocols and embedded digital signal processing will also be discussed

  7. Spectroelectrochemical Instrument Measures TOC

    Science.gov (United States)

    Kounaves, Sam

    2011-01-01

    A spectroelectrochemical instrument has been developed for measuring the total organic carbon (TOC) content of an aqueous solution. Measurements of TOC are frequently performed in environmental, clinical, and industrial settings. Until now, techniques for performing such measurements have included, various ly, the use of hazardous reagents, ultraviolet light, or ovens, to promote reactions in which the carbon contents are oxidized. The instrument now being developed is intended to be a safer, more economical means of oxidizing organic carbon and determining the TOC levels of aqueous solutions and for providing a low power/mass unit for use in planetary missions.

  8. Neutron multiplication measurement instrument

    International Nuclear Information System (INIS)

    Nixon, K.V.; Dowdy, E.J.; France, S.W.; Millegan, D.R.; Robba, A.A.

    1983-01-01

    The Advanced Nuclear Technology Group of the Los Alamos National Laboratory is now using intelligent data-acquisition and analysis instrumentation for determining the multiplication of nuclear material. Earlier instrumentation, such as the large NIM-crate systems, depended on house power and required additional computation to determine multiplication or to estimate error. The portable, battery-powered multiplication measurement unit, with advanced computational power, acquires data, calculates multiplication, and completes error analysis automatically. Thus, the multiplication is determined easily and an available error estimate enables the user to judge the significance of results

  9. Standard NIM instrumentation system

    International Nuclear Information System (INIS)

    1990-05-01

    NIM is a standard modular instrumentation system that is in wide use throughout the world. As the NIM system developed and accommodations were made to a dynamic instrumentation field and a rapidly advancing technology, additions, revisions and clarifications were made. These were incorporated into the standard in the form of addenda and errata. This standard is a revision of the NIM document, AEC Report TID-20893 (Rev. 4) dated July 1974. It includes all the addenda and errata items that were previously issued as well as numerous additional items to make the standard current with modern technology and manufacturing practice

  10. Virtual Reality Musical Instruments

    DEFF Research Database (Denmark)

    Serafin, Stefania; Erkut, Cumhur; Kojs, Juraj

    2016-01-01

    The rapid development and availability of low-cost technologies have created a wide interest in virtual reality. In the field of computer music, the term “virtual musical instruments” has been used for a long time to describe software simulations, extensions of existing musical instruments......, and ways to control them with new interfaces for musical expression. Virtual reality musical instruments (VRMIs) that include a simulated visual component delivered via a head-mounted display or other forms of immersive visualization have not yet received much attention. In this article, we present a field...

  11. ICFA: Instrumentation school

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    74 students, including 45 from developing countries, ten lecturers and nine laboratory instructors participated in the novel instrumentation school held in June at the International Centre for Theoretical Physics (ICTP), Trieste, Italy, sponsored by ICTP and arranged through the Instrumentation Panel of the International Committee for Future Accelerators (ICF). During the two weeks of the course, students had the chance to construct and test a proportional chamber, measure the lifetime of cosmic ray muons, operate and analyse the performance of an 8-wire imaging drift chamber, or study noise and signal processing using a silicon photodiode

  12. Instrumentation Cables Test Plan

    Energy Technology Data Exchange (ETDEWEB)

    Muna, Alice Baca [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); LaFleur, Chris Bensdotter [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2016-10-01

    A fire at a nuclear power plant (NPP) has the potential to damage structures, systems, and components important to safety, if not promptly detected and suppressed. At Browns Ferry Nuclear Power Plant on March 22, 1975, a fire in the reactor building damaged electrical power and control systems. Damage to instrumentation cables impeded the function of both normal and standby reactor coolant systems, and degraded the operators’ plant monitoring capability. This event resulted in additional NRC involvement with utilities to ensure that NPPs are properly protected from fire as intended by the NRC principle design criteria (i.e., general design criteria 3, Fire Protection). Current guidance and methods for both deterministic and performance based approaches typically make conservative (bounding) assumptions regarding the fire-induced failure modes of instrumentation cables and those failure modes effects on component and system response. Numerous fire testing programs have been conducted in the past to evaluate the failure modes and effects of electrical cables exposed to severe thermal conditions. However, that testing has primarily focused on control circuits with only a limited number of tests performed on instrumentation circuits. In 2001, the Nuclear Energy Institute (NEI) and the Electric Power Research Institute (EPRI) conducted a series of cable fire tests designed to address specific aspects of the cable failure and circuit fault issues of concern1. The NRC was invited to observe and participate in that program. The NRC sponsored Sandia National Laboratories to support this participation, whom among other things, added a 4-20 mA instrumentation circuit and instrumentation cabling to six of the tests. Although limited, one insight drawn from those instrumentation circuits tests was that the failure characteristics appeared to depend on the cable insulation material. The results showed that for thermoset insulated cables, the instrument reading tended to drift

  13. Celadon Figurines Play Instruments

    Institute of Scientific and Technical Information of China (English)

    1995-01-01

    This group of figurines, each 0.15m tall, were unearthed from a Tang Dynasty tomb in Changsha in 1977. Music was very developed in the Tang Dynasty. Colorful musical instruments and dances were popular both among the people and in the palace. These vivid-looking figurines wear pleated skirts with small sleeves and open chest, a style influenced by the non-Han nationalities living in the north and west of China. Some of the musical instruments were brought from the Western Regions. The figurines are playing the xiao (a vertical bamboo flute), the konghou (an

  14. Inspector-instrument interface in portable NDA instrumentation

    International Nuclear Information System (INIS)

    Halbig, J.K.; Klosterbuer, S.F.

    1981-01-01

    Recent electronics technology advances make it possible to design sophisticated instruments in small packages for convenient field implementation. An inspector-instrument interface design that allows communication of procedures, responses, and results between the instrument and user is presented. This capability has been incorporated into new spent-fuel instrumentation and a battery-powered multichannel analyzer

  15. Inspector-instrument interface in portable NDA instrumentation

    International Nuclear Information System (INIS)

    Halbig, J.K.; Klosterbuer, S.F.

    1981-01-01

    Recent electronics technology advances make it possible to design sophisticated instruments in small packages for convenient field implementation. This report describes an inspector-instrument interface design which allows communication of procedures, responses, and results between the instrument and user. The interface has been incorporated into new spent-fuel instrumentation and a battery-powered multichannel analyzer

  16. Power station instrumentation

    International Nuclear Information System (INIS)

    Jervis, M.W.

    1993-01-01

    Power stations are characterized by a wide variety of mechanical and electrical plant operating with structures, liquids and gases working at high pressures and temperatures and with large mass flows. The voltages and currents are also the highest that occur in most industries. In order to achieve maximum economy, the plant is operated with relatively small margins from conditions that can cause rapid plant damage, safety implications, and very high financial penalties. In common with other process industries, power stations depend heavily on control and instrumentation. These systems have become particularly significant, in the cost-conscious privatized environment, for providing the means to implement the automation implicit in maintaining safety standards, improving generation efficiency and reducing operating manpower costs. This book is for professional instrumentation engineers who need to known about their use in power stations and power station engineers requiring information about the principles and choice of instrumentation available. There are 8 chapters; chapter 4 on instrumentation for nuclear steam supply systems is indexed separately. (Author)

  17. University Reactor Instrumentation Program

    International Nuclear Information System (INIS)

    Vernetson, W.G.

    1992-11-01

    Recognizing that the University Reactor Instrumentation Program was developed in response to widespread needs in the academic community for modernization and improvement of research and training reactors at institutions such as the University of Florida, the items proposed to be supported by this grant over its two year period have been selected as those most likely to reduce foreed outages, to meet regulatory concerns that had been expressed in recent years by Nuclear Regulatory Commission inspectors or to correct other facility problems and limitations. Department of Energy Grant Number DE-FG07-90ER129969 was provided to the University of Florida Training Reactor(UFTR) facility through the US Department of Energy's University Reactor Instrumentation Program. The original proposal submitted in February, 1990 requested support for UFTR facility instrumentation and equipment upgrades for seven items in the amount of $107,530 with $13,800 of this amount to be the subject of cost sharing by the University of Florida and $93,730 requested as support from the Department of Energy. A breakdown of the items requested and total cost for the proposed UFTR facility instrumentation and equipment improvements is presented

  18. Neutron instrumentation for biology

    Energy Technology Data Exchange (ETDEWEB)

    Mason, S.A. [Institut Laue-Langevin, Grenoble (France)

    1994-12-31

    In the October 1994 round of proposals at the ILL, the external biology review sub- committee was asked to allocate neutron beam time to a wide range of experiments, on almost half the total number of scheduled neutron instruments: on 3 diffractometers, on 3 small angle scattering instruments, and on some 6 inelastic scattering spectrometers. In the 3.5 years since the temporary reactor shutdown, the ILL`s management structure has been optimized, budgets and staff have been trimmed, the ILL reactor has been re-built, and many of the instruments up-graded, many powerful (mainly Unix) workstations have been introduced, and the neighboring European Synchrotron Radiation Facility has established itself as the leading synchrotron radiation source and has started its official user program. The ILL reactor remains the world`s most intense dedicated neutron source. In this challenging context, it is of interest to review briefly the park of ILL instruments used to study the structure and energetics of small and large biological systems. A brief summary will be made of each class of experiments actually proposed in the latest ILL proposal round.

  19. The ozone monitoring instrument

    NARCIS (Netherlands)

    Levelt, P.F.; Oord, G.H.J. van den; Dobber, M.R.; Mälkki, A.; Visser, H.; Vries, J. de; Stammes, P.; Lundell, J.O.V.; Saari, H.

    2006-01-01

    The Ozone Monitoring Instrument (OMI) flies on the National Aeronautics and Space Adminsitration's Earth Observing System Aura satellite launched in July 2004. OMI is a ultraviolet/visible (UV/VIS) nadir solar backscatter spectrometer, which provides nearly global coverage in one day with a spatial

  20. Economic Policy Instruments

    DEFF Research Database (Denmark)

    Klemmensen, Børge

    2007-01-01

    Økonomiske instrumenter begrundes med behovet for politiske indgreb, der muliggør internaliseringen af omkostningerne ved de miljøpåvirkninger, produktion and levevis afstedkommer, således at hensyntagen til miljøet bliver en del af virksomheders og husholdningers omkostninger og dermed en tilsky...

  1. Radiometric well logging instruments

    International Nuclear Information System (INIS)

    Davydov, A.V.

    1975-01-01

    The technical properties of well instruments for radioactive logging used in the radiometric logging complexes PKS-1000-1 (''Sond-1'') and PRKS-2 (''Vitok-2'') are described. The main features of the electric circuit of the measuring channels are given

  2. Advanced instrumentation and teleoperation

    International Nuclear Information System (INIS)

    Decreton, M.

    1998-01-01

    SCK-CEN's advanced instrumentation and teleoperation project aims at evaluating the potential of a telerobotic approach in a nuclear environment and, in particular, the use of remote-perception systems. Main achievements in 1997 in the areas of R and D on radiation tolerance for remote sensing, optical fibres and optical-fibre sensors, and computer-aided teleoperation are reported

  3. Health physics instrumentation needs

    International Nuclear Information System (INIS)

    Selby, J.M.; Swinth, K.L.; Kenoyer, J.L.

    1984-10-01

    Deficiencies and desirable improvements can be identified in every technical area in which health physics instruments are employed. The needed improvements cover the full spectrum including long-term reliability, human factors, accuracy, ruggedness, ease of calibration, improved radiation response, and improved mixed field response. Some specific areas of deficiency noted along with needed improvements. 17 references

  4. Virtual reality musical instruments

    DEFF Research Database (Denmark)

    Serafin, Stefania; Erkut, Cumhur; Kojs, Juraj

    2016-01-01

    The rapid development and availability of low cost technologies has created a wide interest in virtual reality (VR), but how to design and evaluate multisensory interactions in VR remains as a challenge. In this paper, we focus on virtual reality musical instruments, present an overview of our...

  5. Creating a Super Instrument

    DEFF Research Database (Denmark)

    Kallionpää, Maria; Gasselseder, Hans-Peter

    2015-01-01

    Thanks to the development of new technology, musical instruments are no more tied to their existing acoustic or technical limitations as almost all parameters can be augmented or modified in real time. An increasing number of composers, performers, and computer programmers have thus become intere...

  6. CMO Site: Ocean Instrumentation

    Science.gov (United States)

    1997-02-01

    Precipitation , Lightning, Visibility 0150 A InterOcea Hawser Strain 1.. systems, inc. and more... n 1946 3540 aero court san diego ca 92123-1799 usa phone: (619...AGU’s Microgal culture Association, P.O. Box 1004, April 8-10, 1997-Underwater Gravimetry : Instruments, Observa- Niland, CA 92257; (619) 359-3474

  7. Instrumentation in thermoluminescence dosimetry

    International Nuclear Information System (INIS)

    Julius, H.W.

    1986-01-01

    In the performance of a thermoluminescence dosimetry (TLD) system the equipment plays an important role. Crucial parameters of instrumentation in TLD are discussed in some detail. A review is given of equipment available on the market today - with some emphasis on automation - which is partly based on information from industry and others involved in research and development. (author)

  8. Ion chamber instrument

    International Nuclear Information System (INIS)

    Stephan, D.H.

    1975-01-01

    An electrical ionization chamber is described having a self-supporting wall of cellular material which is of uniform areal density and formed of material, such as foamed polystyrene, having an average effective atomic number between about 4 and about 9, and easily replaceable when on the instrument. (auth)

  9. Integrating Nephelometer Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Uin, J. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2016-03-01

    The Integrating Nephelometer (Figure 1) is an instrument that measures aerosol light scattering. It measures aerosol optical scattering properties by detecting (with a wide angular integration – from 7 to 170°) the light scattered by the aerosol and subtracting the light scattered by the carrier gas, the instrument walls and the background noise in the detector (zeroing). Zeroing is typically performed for 5 minutes every day at midnight UTC. The scattered light is split into red (700 nm), green (550 nm), and blue (450 nm) wavelengths and captured by three photomultiplier tubes. The instrument can measure total scatter as well as backscatter only (from 90 to 170°) (Heintzenberg and Charlson 1996; Anderson et al. 1996; Anderson and Ogren 1998; TSI 3563 2015) At ARM (Atmospheric Radiation Measurement), two identical Nephelometers are usually run in series with a sample relative humidity (RH) conditioner between them. This is possible because Nephelometer sampling is non-destructive and the sample can be passed on to another instrument. The sample RH conditioner scans through multiple RH values in cycles, treating the sample. This kind of setup allows to study how aerosol particles’ light scattering properties are affected by humidification (Anderson et al. 1996). For historical reasons, the two Nephelometers in this setup are labeled “wet” and “dry”, with the “dry” Nephelometer usually being the one before the conditioner and sampling ambient air (the names are switched for the MAOS measurement site due to the high RH of the ambient air).

  10. Measurement and Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Kirkham, Harold

    2018-01-02

    This is a chapter for a book called the Standard Handbook for Electrical Engineering. Though it is not obvious from the title, the book deals mainly with power engineering. The first chapter (not mine) is about the fundamental quantities used in measurement. This chapter is about the process and the instrumentation.

  11. Analytical chemistry instrumentation

    International Nuclear Information System (INIS)

    Laing, W.R.

    1986-01-01

    In nine sections, 48 chapters cover 1) analytical chemistry and the environment 2) environmental radiochemistry 3) automated instrumentation 4) advances in analytical mass spectrometry 5) fourier transform spectroscopy 6) analytical chemistry of plutonium 7) nuclear analytical chemistry 8) chemometrics and 9) nuclear fuel technology

  12. CRISP instrument manual

    International Nuclear Information System (INIS)

    Bucknall, D.G.; Langridge, Sean

    1997-05-01

    This document is a user manual for CRISP, one of the two neutron reflectomers at ISIS. CRISP is highly automated allowing precision reproducible measurements. The manual provides detailed instructions for the setting-up and running of the instrument and advice on data analysis. (UK)

  13. The Science of String Instruments

    CERN Document Server

    Rossing, Thomas D

    2010-01-01

    Many performing musicians, as well as instrument builders, are coming to realize the importance of understanding the science of musical instruments. This book explains how string instruments produce sound. It presents basic ideas in simple language, and it also translates some more sophisticated ideas in non-technical language. It should be of interest to performers, researchers, and instrument makers alike.

  14. netherland hydrological modeling instrument

    Science.gov (United States)

    Hoogewoud, J. C.; de Lange, W. J.; Veldhuizen, A.; Prinsen, G.

    2012-04-01

    Netherlands Hydrological Modeling Instrument A decision support system for water basin management. J.C. Hoogewoud , W.J. de Lange ,A. Veldhuizen , G. Prinsen , The Netherlands Hydrological modeling Instrument (NHI) is the center point of a framework of models, to coherently model the hydrological system and the multitude of functions it supports. Dutch hydrological institutes Deltares, Alterra, Netherlands Environmental Assessment Agency, RWS Waterdienst, STOWA and Vewin are cooperating in enhancing the NHI for adequate decision support. The instrument is used by three different ministries involved in national water policy matters, for instance the WFD, drought management, manure policy and climate change issues. The basis of the modeling instrument is a state-of-the-art on-line coupling of the groundwater system (MODFLOW), the unsaturated zone (metaSWAP) and the surface water system (MOZART-DM). It brings together hydro(geo)logical processes from the column to the basin scale, ranging from 250x250m plots to the river Rhine and includes salt water flow. The NHI is validated with an eight year run (1998-2006) with dry and wet periods. For this run different parts of the hydrology have been compared with measurements. For instance, water demands in dry periods (e.g. for irrigation), discharges at outlets, groundwater levels and evaporation. A validation alone is not enough to get support from stakeholders. Involvement from stakeholders in the modeling process is needed. There fore to gain sufficient support and trust in the instrument on different (policy) levels a couple of actions have been taken: 1. a transparent evaluation of modeling-results has been set up 2. an extensive program is running to cooperate with regional waterboards and suppliers of drinking water in improving the NHI 3. sharing (hydrological) data via newly setup Modeling Database for local and national models 4. Enhancing the NHI with "local" information. The NHI is and has been used for many

  15. Developments in analytical instrumentation

    Science.gov (United States)

    Petrie, G.

    The situation regarding photogrammetric instrumentation has changed quite dramatically over the last 2 or 3 years with the withdrawal of most analogue stereo-plotting machines from the market place and their replacement by analytically based instrumentation. While there have been few new developments in the field of comparators, there has been an explosive development in the area of small, relatively inexpensive analytical stereo-plotters based on the use of microcomputers. In particular, a number of new instruments have been introduced by manufacturers who mostly have not been associated previously with photogrammetry. Several innovative concepts have been introduced in these small but capable instruments, many of which are aimed at specialised applications, e.g. in close-range photogrammetry (using small-format cameras); for thematic mapping (by organisations engaged in environmental monitoring or resources exploitation); for map revision, etc. Another innovative and possibly significant development has been the production of conversion kits to convert suitable analogue stereo-plotting machines such as the Topocart, PG-2 and B-8 into fully fledged analytical plotters. The larger and more sophisticated analytical stereo-plotters are mostly being produced by the traditional mainstream photogrammetric systems suppliers with several new instruments and developments being introduced at the top end of the market. These include the use of enlarged photo stages to handle images up to 25 × 50 cm format; the complete integration of graphics workstations into the analytical plotter design; the introduction of graphics superimposition and stereo-superimposition; the addition of correlators for the automatic measurement of height, etc. The software associated with this new analytical instrumentation is now undergoing extensive re-development with the need to supply photogrammetric data as input to the more sophisticated G.I.S. systems now being installed by clients, instead

  16. A GC Instrument Simulator

    Science.gov (United States)

    Armitage, D. Bruce

    1999-02-01

    This simulator was developed to help students beginning the study of gas chromatographic instruments to understand their operation. It is not meant to teach chromatographic theory. The instrument simulator is divided into 5 sections. One is for sample preparation. Another is used to manage carrier gases and choose a detector and column. The third sets the conditions for either isothermal or programmed temperature operation. A fourth section models manual injections, and the fifth is the autosampler. The operator has a choice among 6 columns of differing diameters and packing polarities and a choice of either isothermal or simple one-stage temperature programming. The simulator can be operated in either single-sample mode or as a 10-sample autosampler. The integrator has two modes of operation, a "dumb" mode in which only the retention time, area of the peak, and percentage area are listed and a "smart" mode that also lists the components' identities. The identities are obtained from a list of names and retention times created by the operator. Without this list only the percentages and areas are listed. The percentages are based on the areas obtained from the chromatogram and not on the actual percentages assigned during sample preparation. The data files for the compounds used in the simulator are ASCII files and can be edited easily to add more compounds than the 11 included with the simulator. A maximum of 10 components can be used in any one sample. Sample mixtures can be made on a percent-by-volume basis, but not by mass of sample per volume of solvent. A maximum of 30 compounds can be present in any one file, but the number of files is limited only by the operating system. (I suggest that not more than 20 compounds be used in any one file, as scrolling through large numbers of compounds is annoying to say the least.) File construction and layout are discussed in detail in the User's Manual. Chromatograms are generated by calculating a retention time based on

  17. Data acquisition instruments: Psychopharmacology

    Energy Technology Data Exchange (ETDEWEB)

    Hartley, D.S. III

    1998-01-01

    This report contains the results of a Direct Assistance Project performed by Lockheed Martin Energy Systems, Inc., for Dr. K. O. Jobson. The purpose of the project was to perform preliminary analysis of the data acquisition instruments used in the field of psychiatry, with the goal of identifying commonalities of data and strategies for handling and using the data in the most advantageous fashion. Data acquisition instruments from 12 sources were provided by Dr. Jobson. Several commonalities were identified and a potentially useful data strategy is reported here. Analysis of the information collected for utility in performing diagnoses is recommended. In addition, further work is recommended to refine the commonalities into a directly useful computer systems structure.

  18. Social Responsibility Instruments

    Directory of Open Access Journals (Sweden)

    Katarzyna Mizera

    2008-09-01

    Full Text Available Responsible business notion is more and more present in Polish economy, however the results of the research carried out in Polish business still shows a low level of CRS idea knowledge, especially in small and medium companies. Although responsible business notion is generally known, its details, ways of preparing strategy, instruments and what is more its benefits are still narrowly spread. Many business people face the lack of knowledge and information, which on one hand make it easier to spread and deepen wrong stereotypes connected with this notion and on the other hand make business people unwilling to implement CRS in their companies. The subjects of this article are examples of instruments which are responsible for realization of social responsibility strategy.

  19. Radiation measuring instrument

    International Nuclear Information System (INIS)

    Genrich, V.

    1985-01-01

    A highly sensitive and compactly structured radiation measuring instrument for detecting ionizing radiation, in particular for measuring dose rates and contamination. The laminar structure of the associated counter tube, using only a few, simple plastic parts and a highly elastic counter wire, makes it possible to use the simplest manufacturing techniques. The service life of the counter tube construction, which is completely and permanently sealed and filled with gas, is expected to be more than 12 years. The described counter tube can be adapted in optimal fashion to the available space in a pocket instrument if it is used in combination with a specialized high-voltage generator which is low in interference voltage and with a pulse evaluation circuit having a means of compensating for interference voltage

  20. Radon-Instrumentation

    International Nuclear Information System (INIS)

    Moreno y Moreno, A.

    2003-01-01

    The presentation of the active and passive methods for radon, their identification and measure, instrumentation and characteristics are the objectives of this work. Active detectors: Active Alpha Cam Continuous Air Monitor, Model 758 of Victoreen, Model CMR-510 Continuous Radon Monitor of the Signature Femto-Tech. Passive detectors: SSNTD track detectors in solids Measurement Using Charcoal Canisters, disk of activated coal deposited in a metallic box Electrets Methodology. (Author)

  1. Testing Aircraft Instruments.

    Science.gov (United States)

    1981-02-11

    1. Have test data been collected, recorded, and presented in accordance with this TOP? Yes No Comment : 2. Were the facilities, test equipment...instrumentation, and support accommodations adequate to accomplish the test objectives? Yes No Comment : 3. Have all data collected been reviewed for...correctness and completeness? Yes No Comment : 4. Were the test results compromised in any way due to insufficient test planning? Yes No Comment : 5. Were the

  2. Transgressive or Instrumental?

    DEFF Research Database (Denmark)

    Chemi, Tatiana

    2018-01-01

    Contemporary practices that connect the arts with learning are widespread at all level of educational systems and in organisations, but they include very diverse approaches, multiple methods and background values. Regardless of explicit learning benefits, the arts/learning partnerships bring about...... creativity and the other on practices of arts-integration. My final point rests on the belief that the opposition of transgression and instrumentality is a deceiving perspective on the arts, against the background of the aesthetic plurality and hybridity....

  3. EPRTM Reactor neutron instrumentation

    International Nuclear Information System (INIS)

    Pfeiffer, Maxime; SALA, Stephanie

    2013-06-01

    The core safety during operation is linked, in particular, to the respect of criteria related to the heat generated in fuel rods and to the heat exchange between the rods and the coolant. This local power information is linked to the power distribution in the core. In order to evaluate the core power distribution, the EPR TM reactor relies on several types of neutron detectors: - ionization chambers located outside the vessel and used for protection and monitoring - a fixed in-core instrumentation based on Cobalt Self Powered Neutron Detectors used for protection and monitoring - a mobile reference in-core instrumentation based on Vanadium aero-balls This document provides a description of this instrumentation and its use in core protection, limitation, monitoring and control functions. In particular, a description of the detectors and the principles of their signal generation is supplied as well as the description of the treatments related to these detectors in the EPR TM reactor I and C systems (including periodical calibration). (authors)

  4. Mandolin Family Instruments

    Science.gov (United States)

    Cohen, David J.; Rossing, Thomas D.

    The mandolin family of instruments consists of plucked chordophones, each having eight strings in four double courses. With the exception of the mandobass, the courses are tuned in intervals of fifths, as are the strings in violin family instruments. The soprano member of the family is the mandolin, tuned G3-D4-A4-E5. The alto member of the family is the mandola, tuned C3-G3-D4-A4. The mandola is usually referred to simply as the mandola in the USA, but is called the tenor mandola in Europe. The tenor member of the family is the octave mandolin, tuned G2-D3-A3-E4. It is referred to as the octave mandolin in the USA, and as the octave mandola in Europe. The baritone member of the family is the mandocello, or mandoloncello, tuned C2-G2-D3-A3. A variant of the mandocello not common in the USA is the five-course liuto moderno, or simply liuto, designed for solo repertoire. Its courses are tuned C2-G2-D3-A3-E4. A mandobass was also made by more than one manufacturer during the early twentieth century, though none are manufactured today. They were fretted instruments with single string courses tuned E1-A1-D2-G2. There are currently a few luthiers making piccolo mandolins, tuned C4-G4-D5-A5.

  5. Nuclear reactor instrumentation

    International Nuclear Information System (INIS)

    Duncombe, E.; McGonigal, G.

    1976-01-01

    Reference is made to the instrumentation of liquid metal cooled fast reactors. In order to ensure the safe operation of such reactors it is necessary to constantly monitor the coolant flowing through the fuel assemblies for temperature and rate of flow, requiring a large number of sensors. An improved and simplified arrangement is claimed in which the fuel assemblies feed a fraction of coolant to three instrument units arranged to sense the temperature and rate of flow of samples of coolant. Each instrument unit comprises a sleeve housing a sensing unit and has a number of inlet ducts arranged for receiving coolant from a fuel assembly together with a single outlet. The sensing unit has three thermocouple hot junctions connected in series, the hot junctions and inlet ducts being arranged in pairs. Electromagnetic windings around an inductive core are arranged to sense variation in flow of liquid metal by flux distortion. Fission product sensing means may also be provided. Full constructional details are given. (U.K.)

  6. CARMENES instrument overview

    Science.gov (United States)

    Quirrenbach, A.; Amado, P. J.; Caballero, J. A.; Mundt, R.; Reiners, A.; Ribas, I.; Seifert, W.; Abril, M.; Aceituno, J.; Alonso-Floriano, F. J.; Ammler-von Eiff, M.; Antona Jiménez, R.; Anwand-Heerwart, H.; Azzaro, M.; Bauer, F.; Barrado, D.; Becerril, S.; Béjar, V. J. S.; Benítez, D.; Berdiñas, Z. M.; Cárdenas, M. C.; Casal, E.; Claret, A.; Colomé, J.; Cortés-Contreras, M.; Czesla, S.; Doellinger, M.; Dreizler, S.; Feiz, C.; Fernández, M.; Galadí, D.; Gálvez-Ortiz, M. C.; García-Piquer, A.; García-Vargas, M. L.; Garrido, R.; Gesa, L.; Gómez Galera, V.; González Álvarez, E.; González Hernández, J. I.; Grözinger, U.; Guàrdia, J.; Guenther, E. W.; de Guindos, E.; Gutiérrez-Soto, J.; Hagen, H.-J.; Hatzes, A. P.; Hauschildt, P. H.; Helmling, J.; Henning, T.; Hermann, D.; Hernández Castaño, L.; Herrero, E.; Hidalgo, D.; Holgado, G.; Huber, A.; Huber, K. F.; Jeffers, S.; Joergens, V.; de Juan, E.; Kehr, M.; Klein, R.; Kürster, M.; Lamert, A.; Lalitha, S.; Laun, W.; Lemke, U.; Lenzen, R.; López del Fresno, Mauro; López Martí, B.; López-Santiago, J.; Mall, U.; Mandel, H.; Martín, E. L.; Martín-Ruiz, S.; Martínez-Rodríguez, H.; Marvin, C. J.; Mathar, R. J.; Mirabet, E.; Montes, D.; Morales Muñoz, R.; Moya, A.; Naranjo, V.; Ofir, A.; Oreiro, R.; Pallé, E.; Panduro, J.; Passegger, V.-M.; Pérez-Calpena, A.; Pérez Medialdea, D.; Perger, M.; Pluto, M.; Ramón, A.; Rebolo, R.; Redondo, P.; Reffert, S.; Reinhardt, S.; Rhode, P.; Rix, H.-W.; Rodler, F.; Rodríguez, E.; Rodríguez-López, C.; Rodríguez-Pérez, E.; Rohloff, R.-R.; Rosich, A.; Sánchez-Blanco, E.; Sánchez Carrasco, M. A.; Sanz-Forcada, J.; Sarmiento, L. F.; Schäfer, S.; Schiller, J.; Schmidt, C.; Schmitt, J. H. M. M.; Solano, E.; Stahl, O.; Storz, C.; Stürmer, J.; Suárez, J. C.; Ulbrich, R. G.; Veredas, G.; Wagner, K.; Winkler, J.; Zapatero Osorio, M. R.; Zechmeister, M.; Abellán de Paco, F. J.; Anglada-Escudé, G.; del Burgo, C.; Klutsch, A.; Lizon, J. L.; López-Morales, M.; Morales, J. C.; Perryman, M. A. C.; Tulloch, S. M.; Xu, W.

    2014-07-01

    This paper gives an overview of the CARMENES instrument and of the survey that will be carried out with it during the first years of operation. CARMENES (Calar Alto high-Resolution search for M dwarfs with Exoearths with Near-infrared and optical Echelle Spectrographs) is a next-generation radial-velocity instrument under construction for the 3.5m telescope at the Calar Alto Observatory by a consortium of eleven Spanish and German institutions. The scientific goal of the project is conducting a 600-night exoplanet survey targeting ~ 300 M dwarfs with the completed instrument. The CARMENES instrument consists of two separate echelle spectrographs covering the wavelength range from 0.55 to 1.7 μm at a spectral resolution of R = 82,000, fed by fibers from the Cassegrain focus of the telescope. The spectrographs are housed in vacuum tanks providing the temperature-stabilized environments necessary to enable a 1 m/s radial velocity precision employing a simultaneous calibration with an emission-line lamp or with a Fabry-Perot etalon. For mid-M to late-M spectral types, the wavelength range around 1.0 μm (Y band) is the most important wavelength region for radial velocity work. Therefore, the efficiency of CARMENES has been optimized in this range. The CARMENES instrument consists of two spectrographs, one equipped with a 4k x 4k pixel CCD for the range 0.55 - 1.05 μm, and one with two 2k x 2k pixel HgCdTe detectors for the range from 0.95 - 1.7μm. Each spectrograph will be coupled to the 3.5m telescope with two optical fibers, one for the target, and one for calibration light. The front end contains a dichroic beam splitter and an atmospheric dispersion corrector, to feed the light into the fibers leading to the spectrographs. Guiding is performed with a separate camera; on-axis as well as off-axis guiding modes are implemented. Fibers with octagonal cross-section are employed to ensure good stability of the output in the presence of residual guiding errors. The

  7. Instrumentation for environmental monitoring: biomedical

    International Nuclear Information System (INIS)

    1979-05-01

    An update is presented to Volume four of the six-volume series devoted to a survey of instruments useful for measurements in biomedicine related to environmental research and monitoring. Results of the survey are given as descriptions of the physical and operating characteristics of available instruments, critical comparisons among instrumentation methods, and recommendations of promising methodology and development of new instrumentation. Methods of detection and analysis of gaseous organic pollutants and metals, including Ni and As are presented. Instrument techniques and notes are included on atomic spectrometry and uv and visible absorption instrumentation

  8. Payment Instrument Characteristics

    DEFF Research Database (Denmark)

    Holst, Jacques; Kjeldsen, Martin; Hedman, Jonas

    2015-01-01

    Over the last decade, we have witnessed payment innovations that fundamentally have changed the ways we pay. Payment innovations, such as mobile payments and on-line banking, include characteristics or features that are essential to understand if we want to know how and why payers choose among...... payment innovations. Using the Repertory Grid technique to explore 15 payers’ perception of six payment instruments, including coins, banknotes, debit cards, credit cards, mobile payments, and on-line banking, we identify 16 payment characteristics. The characteristics aggregate seventy-six unique...

  9. Operational Test Instrumentation Guide.

    Science.gov (United States)

    1981-11-01

    System. A topographic, transit-level measuring system, instrumented with altimeter, clinometers, compasses , and an alidade, plane table, and stadia rod...dual hangar 250 x 135 feet with two door openings, 80 feet each. There is no compass swing base, no electronic landing aids, ro aircraft wash or...month) of SDG &E) Haybarn Canyon 15,000 6,183,870 Lan Pulgas 1,500 433,890 Las Pulgas Well #41621 100 4,258 Las Pulgas Well #41611 150 7,548 Las Flores

  10. Beam Instrumentation and Diagnostics

    CERN Document Server

    Strehl, Peter

    2006-01-01

    This treatise covers all aspects of the design and the daily operations of a beam diagnostic system for a large particle accelerator. A very interdisciplinary field, it involves contributions from physicists, electrical and mechanical engineers and computer experts alike so as to satisfy the ever-increasing demands for beam parameter variability for a vast range of operation modi and particles. The author draws upon 40 years of research and work, most of them spent as the head of the beam diagnostics group at GSI. He has illustrated the more theoretical aspects with many real-life examples that will provide beam instrumentation designers with ideas and tools for their work.

  11. Instrumentation for tomograph positioning

    International Nuclear Information System (INIS)

    Frenkel, A.D.B.; Castello Branco, L.M.; Reznik, D.S.; Santos, C.A.C.; Borges, J.C.

    1986-01-01

    The COPPE's Nuclear Instrumentation Lab. has been developing researches directed towards the implementation of a Computer-Based Tomography System. Basically, the system reported in this paper can be divided into three major parts: the mechanical part, responsible for the physical movement (Stepper-Motors, table, etc.); the electronic part, which controls the mechanical part and handles the data-acquisition process (microcomputer, interfaces, etc.); and finally, the support of a software-oriented system, including control programs and information processing routines. (Author) [pt

  12. Easy instrumental analysis

    International Nuclear Information System (INIS)

    Ko, Myeong Su; Kim, Tae Hwa; Park, Gyu Hyeon; Yang, Jong Beom; Oh, Chang Hwan; Lee, Kyoung Hye

    2010-04-01

    This textbook describes instrument analysis in easy way with twelve chapters. The contents of the book are pH measurement on principle, pH meter, pH measurement, examples of the experiments, centrifugation, Absorptiometry, Fluorescent method, Atomic absorption analysis, Gas-chromatography, Gas chromatography-mass spectrometry, High performance liquid chromatography liquid chromatograph-mass spectrometry, Electrophoresis on practical case and analysis of the result and examples, PCR on principle, device, application and examples and Enzyme-linked immunosorbent assay with indirect ELISA, sandwich ELISA and ELISA reader.

  13. Maintenance of nuclear instruments

    International Nuclear Information System (INIS)

    Oliveira Rebelo, A.M. de; Santos, C.J.F. dos; Jesus, E.F.O. de; Silva, L.E.M.C.; Borges, J.C.

    1988-01-01

    A program to design and repairing of nuclear instruments for teaching and research was founded in the UFRJ to find solutions for technical support problem - The GEMD-RADIACOES. This group has assisted to several groups of the University in recuperation and conservation of devices like: Linear scanner, Cromatograph and system of radiation detection in general. Recuperation of these devices had required a study of theirs operations modes, to make it possible the setting up of a similar system. Recuperation also involves operation tests, calibration and technical for users, orienting them to get the best performance. (Author) [pt

  14. Easy instrumental analysis

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Myeong Su; Kim, Tae Hwa; Park, Gyu Hyeon; Yang, Jong Beom; Oh, Chang Hwan; Lee, Kyoung Hye

    2010-04-15

    This textbook describes instrument analysis in easy way with twelve chapters. The contents of the book are pH measurement on principle, pH meter, pH measurement, examples of the experiments, centrifugation, Absorptiometry, Fluorescent method, Atomic absorption analysis, Gas-chromatography, Gas chromatography-mass spectrometry, High performance liquid chromatography liquid chromatograph-mass spectrometry, Electrophoresis on practical case and analysis of the result and examples, PCR on principle, device, application and examples and Enzyme-linked immunosorbent assay with indirect ELISA, sandwich ELISA and ELISA reader.

  15. Instruments of Transformative Governance

    DEFF Research Database (Denmark)

    Borrás, Susana

    production and distribution channels. PDPs aim at overcoming current market and government failures by pooling resources in the attempt to solve this global social challenge. Thus, PDPs are a case of instruments of transformative research and innovation, operating in a transnational governance context....... They exhibit three novelties: they address strategic long-term problems in a holistic manner, set substantive output-oriented goals, and are implemented through new organizational structures. After characterizing the different types of current PDPs and the context in which they emerged, the paper examines...

  16. Diamonds for beam instrumentation

    International Nuclear Information System (INIS)

    Griesmayer, Erich

    2013-01-01

    Diamond is perhaps the most versatile, efficient and radiation tolerant material available for use in beam detectors with a correspondingly wide range of applications in beam instrumentation. Numerous practical applications have demonstrated and exploited the sensitivity of diamond to charged particles, photons and neutrons. In this paper, a brief description of a generic diamond detector is given and the interaction of the CVD diamond detector material with protons, electrons, photons and neutrons is presented. Latest results of the interaction of sCVD diamond with 14 MeV mono-energetic neutrons are shown.

  17. Pesticide reducing instruments

    DEFF Research Database (Denmark)

    Jacobsen, Lars-Bo; Jensen, Jørgen Dejgård; Andersen, Martin

    2005-01-01

    -mentioned models and tools. All three scenarios are constructed such that they result in the same welfare implication (measured by national consumption in the CGE model). The scenarios are: 1) pesticide taxes resulting in a 25 percent overall reduction; 2) use of unsprayed field margins, resulting in the same...... for improving bio-diversity and securing drinking water. That is, combining economic modeling with physical biological modeling and geological evaluation allows us to select unsprayed field margins as the most effective instrument. Sensitivity analysis conducted on bio-diversity suggest that this result...

  18. Calibration of radiation monitoring instruments

    International Nuclear Information System (INIS)

    1973-01-01

    Radiation protection is dependent on good radiation monitoring, and properly calibrated instruments are essential for this work. Simple procedures for periodically checking and recalibrating different kinds of radiation monitoring instruments are shown in this training film

  19. Calibration of "Babyline" RP instruments

    CERN Multimedia

    2015-01-01

      If you have old RP instrumentation of the “Babyline” type, as shown in the photo, please contact the Radiation Protection Group (Joffrey Germa, 73171) to have the instrument checked and calibrated. Thank you. Radiation Protection Group

  20. Calibration of radiation monitoring instruments

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1974-12-31

    Radiation protection is dependent on good radiation monitoring, and properly calibrated instruments are essential for this work. Simple procedures for periodically checking and recalibrating different kinds of radiation monitoring instruments are shown in this training film

  1. Instruments for Water Quality Monitoring

    Science.gov (United States)

    Ballinger, Dwight G.

    1972-01-01

    Presents information regarding available instruments for industries and agencies who must monitor numerous aquatic parameters. Charts denote examples of parameters sampled, testing methods, range and accuracy of test methods, cost analysis, and reliability of instruments. (BL)

  2. Nuclear instrumentation for research reactors

    International Nuclear Information System (INIS)

    Hofer, Carlos G.; Pita, Antonio; Verrastro, Claudio A.; Maino, Eduardo J.

    1997-01-01

    The nuclear instrumentation for research reactors in Argentina was developed in 70'. A gradual modernization of all the nuclear instrumentation is planned. It includes start-up and power range instrumentation, as well as field monitors, clamp, scram and rod movement control logic. The new instrumentation is linked to a computer network, based on real time operating system for data acquisition, display and logging. This paper describes the modules and whole system aspects. (author). 2 refs

  3. The QUIET Instrument

    Energy Technology Data Exchange (ETDEWEB)

    Bischoff, C.; et al.

    2012-07-01

    The Q/U Imaging ExperimenT (QUIET) is designed to measure polarization in the Cosmic Microwave Background, targeting the imprint of inflationary gravitational waves at large angular scales ({approx}1{sup o}). Between 2008 October and 2010 December, two independent receiver arrays were deployed sequentially on a 1.4m side-fed Dragonian telescope. The polarimeters which form the focal planes use a highly compact design based on High Electron Mobility Transistors (HEMTs) that provides simultaneous measurements of the Stokes parameters Q, U, and I in a single module. The 17-element Q-band polarimeter array, with a central frequency of 43.1 GHz, has the best sensitivity (69 {mu}Ks{sup 1/2}) and the lowest instrumental systematic errors ever achieved in this band, contributing to the tensor-to-scalar ratio at r < 0:1. The 84-element W-band polarimeter array has a sensitivity of 87 {mu}Ks{sup 1/2} at a central frequency of 94.5 GHz. It has the lowest systematic errors to date, contributing at r < 0:01. The two arrays together cover multipoles in the range {ell} {approx} 25 -- 975. These are the largest HEMT-based arrays deployed to date. This article describes the design, calibration, performance of, and sources of systematic error for the instrument.

  4. Nuclear electronic instrumentation

    International Nuclear Information System (INIS)

    Ramirez J, F. J.

    2010-01-01

    The activities carried out in the Instituto Nacional de Investigaciones Nucleares (ININ) in the field of the nuclear electronic instrumentation included those activities corresponding to the design and production of nuclear instruments in a first stage, as well as the internal activities of design, repair and maintenance that have supported to other projects of the institution during many years. It is mentioned of the presence and constant collaboration of the ININ with the IAEA in different projects and programs. Also, it is mentioned on the establishment of the Radiation Detectors Laboratory, which for their characteristics and repair capacities of radiation detectors of cooled semiconductor, it is only in their specialty. It is emphasized the investigation and the development in the field of new radiation detectors and applications, as well as the important contribution in this field, in institutions like: Mexican Petroleum, National Commission of Nuclear Safety and Safeguards and Federal Commission of Electricity. Finally a position of the future of these activities is made, considering the speed of the advances of the electronic and nuclear technology. (Author)

  5. Neutron instrumentation system

    International Nuclear Information System (INIS)

    Akiyama, Takao; Arita, Setsuo; Yuchi, Hiroyuki

    1989-01-01

    The neutron instrumentation system of this invention can greatly reduce the possibility that the shutdown flux is increased greater than a predetermiend value to cause scram due to vibrations caused by earthquakes or shocks in the neutron instrumentation system without injuring the reactor safety. That is, a sensor having a zero sensitivity to a neutron flux which is an object to be detected by the sensor (dummy sensor) is used together with a conventional sensor (a sensor having predetermined sensitivity to a neutron flux as an object to be measured ----- true sensor). Further, identical signal transmission cables, connector and the signal processing circuits are used for both of true sensor and the dummy sensor. The signal from the dummy sensor is subtracted from the signal from the true sensor at the output of the signal processing circuit. Since the output of the dummy sensor is zero during normal operation, the subtracted value is the same as the value from the true sensor. If the true sensor causes an output with the reason other than the neutron flux, this is outputted also from the dummy sensor but does not appear in the subtracted value. (I.S.)

  6. Incore instrument device

    International Nuclear Information System (INIS)

    Sakima, Naoki

    1996-01-01

    An incore instrument device has an integrally disposed touch panel having a function of displaying an operation indication method such as for setting of conditions for incore measurement and information processing and results of the incore measurement and a function capable of conducting operation indication such as for setting conditions and information processing for incore measurement relative to a control section upon touching an information position on a displayed information. In addition, an information processing section comprising a man-machine function program formed so as to recognize the content of the operation indication for the incore measurement by touching and let the control section to conduct it is disposed to the outside by way of a communication interface. In addition, a programming device is disposed for forming and rewriting the program of the man-machine function relative to the information processing section. Then, when various indication operations are conducted upon performing incore measurement, a view point can be concentrated to one predetermined point thereby enabling to improve the operationability without danger. In addition, the programming of the man-machine function does not apply unnecessary load to the control section in the incore instrumentation device. (N.H.)

  7. Balances instruments, manufacturers, history

    CERN Document Server

    Robens, Erich; Kiefer, Susanne

    2014-01-01

    The book deals mainly with direct mass determination by means of a conventional balances. It covers the history of the balance from the beginnings in Egypt earlier than 3000 BC to recent developments. All balance types are described with emphasis on scientific balances. Methods of indirect mass determination, which are applied to very light objects like molecules and the basic particles of matter and celestial bodies, are included.  As additional guidance, today’s manufacturers are listed and the profile of important companies is reviewed. Several hundred photographs, reproductions and drawings show instruments and their uses. This book includes commercial weighing instruments for merchandise and raw materials in workshops as well as symbolic weighing in the ancient Egyptian’s ceremony of ‘Weighing of the Heart’, the Greek fate balance, the Roman  Justitia, Juno Moneta and Middle Ages scenes of the Last Judgement with Jesus or St. Michael and of modern balances. The photographs are selected from the...

  8. Advancements in Actuated Musical Instruments

    DEFF Research Database (Denmark)

    Overholt, Daniel; Berdahl, Edgar; Hamilton, Robert

    2011-01-01

    are physical instruments that have been endowed with virtual qualities controlled by a computer in real-time but which are nevertheless tangible. These instruments provide intuitive and engaging new forms of interaction. They are different from traditional (acoustic) and fully automated (robotic) instruments...

  9. Rio de Janeiro: Instrumentation school

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    Students from Latin America were able to get hands-on experience in state-of-the-art physics instrumentation in this year's School on Instrumentation for High Energy Physics organized by the active Instrumentation Panel of ICFA (the International Committee for Future Accelerators) at the Centro Brasileiro de Pesquicas Fisicas (CBPF), Rio de Janeiro, in July

  10. Instrument Remote Control via the Astronomical Instrument Markup Language

    Science.gov (United States)

    Sall, Ken; Ames, Troy; Warsaw, Craig; Koons, Lisa; Shafer, Richard

    1998-01-01

    The Instrument Remote Control (IRC) project ongoing at NASA's Goddard Space Flight Center's (GSFC) Information Systems Center (ISC) supports NASA's mission by defining an adaptive intranet-based framework that provides robust interactive and distributed control and monitoring of remote instruments. An astronomical IRC architecture that combines the platform-independent processing capabilities of Java with the power of Extensible Markup Language (XML) to express hierarchical data in an equally platform-independent, as well as human readable manner, has been developed. This architecture is implemented using a variety of XML support tools and Application Programming Interfaces (API) written in Java. IRC will enable trusted astronomers from around the world to easily access infrared instruments (e.g., telescopes, cameras, and spectrometers) located in remote, inhospitable environments, such as the South Pole, a high Chilean mountaintop, or an airborne observatory aboard a Boeing 747. Using IRC's frameworks, an astronomer or other scientist can easily define the type of onboard instrument, control the instrument remotely, and return monitoring data all through the intranet. The Astronomical Instrument Markup Language (AIML) is the first implementation of the more general Instrument Markup Language (IML). The key aspects of our approach to instrument description and control applies to many domains, from medical instruments to machine assembly lines. The concepts behind AIML apply equally well to the description and control of instruments in general. IRC enables us to apply our techniques to several instruments, preferably from different observatories.

  11. Astronomical Instrumentation System Markup Language

    Science.gov (United States)

    Goldbaum, Jesse M.

    2016-05-01

    The Astronomical Instrumentation System Markup Language (AISML) is an Extensible Markup Language (XML) based file format for maintaining and exchanging information about astronomical instrumentation. The factors behind the need for an AISML are first discussed followed by the reasons why XML was chosen as the format. Next it's shown how XML also provides the framework for a more precise definition of an astronomical instrument and how these instruments can be combined to form an Astronomical Instrumentation System (AIS). AISML files for several instruments as well as one for a sample AIS are provided. The files demonstrate how AISML can be utilized for various tasks from web page generation and programming interface to instrument maintenance and quality management. The advantages of widespread adoption of AISML are discussed.

  12. Control of training instrument

    International Nuclear Information System (INIS)

    Seo, K. W.; Joo, Y. C.; Park, J. C.; Hong, C. S.; Choi, I. K.; Cho, B. J.; Lee, H. Y.; Seo, I. S.; Park, N. K.

    1996-01-01

    This report describes the annual results on control of training instrument. The scope and contents are the following: 1. Control of Compact Nuclear Simulator 2. Control of Radiation/Radioactivity Measurement 3. Control of Non-Destructive Testing Equipment 4. Control of Chemical Equipment 5. Control of Personal Computer 6. Other related Lecture Aid Equipment. Efforts were employed to upgrade the training environment through retrofitting experimental facilities, compiling teaching materials and reforcing audio-visual aids. The Nuclear Training Center executed the open-door training courses for 2,496 engineers/scientists from the nuclear regulatory, nuclear industries, research institutes and other related organizations by means of offering 45 training courses during the fiscal year 1995. (author). 15 tabs., 7 figs., 13 refs

  13. Portable musical instrument amplifier

    Science.gov (United States)

    Christian, David E.

    1990-07-24

    The present invention relates to a musical instrument amplifier which is particularly useful for electric guitars. The amplifier has a rigid body for housing both the electronic system for amplifying and processing signals from the guitar and the system's power supply. An input plug connected to and projecting from the body is electrically coupled to the signal amplifying and processing system. When the plug is inserted into an output jack for an electric guitar, the body is rigidly carried by the guitar, and the guitar is operatively connected to the electrical amplifying and signal processing system without use of a loose interconnection cable. The amplifier is provided with an output jack, into which headphones are plugged to receive amplified signals from the guitar. By eliminating the conventional interconnection cable, the amplifier of the present invention can be used by musicians with increased flexibility and greater freedom of movement.

  14. Instrument design and automation

    International Nuclear Information System (INIS)

    Wernlund, R.F.

    1984-01-01

    The ion mobility spectrometer-mass spectrometer (IMS-MS) is described and consists of two separate instruments coupled in tandem: an ion mobility spectrometer coupled to a quadrupole mass spectrometer. The two insturments operate at different pressures in a synergistic manner, supplying both drift time and mass information about ions which are formed at atmospheric pressure in the ion mobility spectrometer tube. Two types of ion intensity signals are presented to the data processor. The IMS produces an analog voltage with major components from dc to 5 KHz. The mass spectrometer signal output resides in the pulse count rate derived from a series of TTL level pulses where each pulse represents the arrival of a single ion. The hardware, software, interfacing capabilities and basic data acquisition program are described in detail

  15. FMIT diagnostic instrumentation

    International Nuclear Information System (INIS)

    Gilpatrick, J.D.; Chamberlin, D.D.

    1985-01-01

    The Fusion Materials Irradiation Test facility (FMIT) cw prototype accelerator has noninterceptive beamline instrumentation to measure beam parameters. The transverse emittances and beam profiles are measured with an array of photodiode sensors viewing light emitted from the beam region. Tomographic reconstructions of both spatial-density distributions and of transverse-emittance distributions are performed throughout a quadrupole focusing section. Beam bunches passing through capacitive probes produce bipolar waveforms whose zero crossing corresponds to the bunch's longitudinal centroid. By measuring the time required for a bunch to travel the known distance between two probes, velocity and energy are determined. A toroidal transformer measures the average ac beam current. Beam spill is measured by a set of movable jaws that intercept the beam edges. Each jaw contains a water flow channel whose flow rate and differential temperature are measured to derive a transverse power distribution. Beam centroid position is measured by a four-lobe, magnetic-loop pickup. 5 refs., 6 figs

  16. Instrumented Pipeline Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Thomas Piro; Michael Ream

    2010-07-31

    This report summarizes technical progress achieved during the cooperative agreement between Concurrent Technologies Corporation (CTC) and U.S. Department of Energy to address the need for a for low-cost monitoring and inspection sensor system as identified in the Department of Energy (DOE) National Gas Infrastructure Research & Development (R&D) Delivery Reliability Program Roadmap.. The Instrumented Pipeline Initiative (IPI) achieved the objective by researching technologies for the monitoring of pipeline delivery integrity, through a ubiquitous network of sensors and controllers to detect and diagnose incipient defects, leaks, and failures. This report is organized by tasks as detailed in the Statement of Project Objectives (SOPO). The sections all state the objective and approach before detailing results of work.

  17. BOMBAY: Instrumentation school

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    Full text: Promising students had a foretaste of the latest laboratory techniques at the ICFA 1993 India School on Instrumentation in High Energy Physics held from February 15-26 and hosted by the Tata Institute of Fundamental Research (TIFR), Bombay. The scientific programme was put together by the ICFA Panel for Future Instrumentation, Innovation and Development, chaired by Tord Ekelof (Uppsala). The programme included lectures and topical seminars covering a wide range of detector subjects. In small groups, students got acquainted with modern detector technologies in the laboratory sessions, using experimental setups assembled in various institutes world-wide and shipped to Bombay for the School. The techniques covered included multiwire proportional chambers for detection of particles and photons, gaseous detectors for UV photons and X-ray imaging, the study of charge drift in silicon detectors, measurement of the muon lifetime using liquid scintillators, tracking using scintillating fibres, and electronics for sensitive detectors. The India School was attended by around 80 students from 20 countries; 34 came from Indian universities. It was the fifth in this series, previous Schools having been at Trieste (1987, 1989 and 1991) organized by the ICFA Panel and hosted and sponsored by the International Centre for Theoretical Physics, and in 1990, organized at Rio de Janeiro in collaboration with the Centro Brasileiro de Pesquisas Fisicas. The School was jointly directed by Suresh Tonwar (TIFR), Fabio Sauli (CERN) and Marleigh Sheaff (University of Wisconsin), and sponsored by TIFR and DAE (India), CERN (Switzerland), ICTP and INFN (Italy), British Council and RAL (UK), NSF and DOE (USA), KEK (Japan), IPP (Canada) and DESY (Germany)

  18. Ideology as instrument.

    Science.gov (United States)

    Glassman, Michael; Karno, Donna

    2007-12-01

    Comments on the article by J. T. Jost, which argued that the end-of-ideology claims that emerged in the aftermath of World War II were both incorrect and detrimental to the field of political psychology. M. Glassman and D. Karno make three critical points. First, Jost objectified ideology as a grand strategy implemented at the individual level, rather than as an instrument used for a specific purpose in activity. In doing so, he set ideology up as an "object" that guides human behavior rather than as a rational part of human experience. Second, they take issue with the idea that, because somebody acts in a manner that can be categorized as ideological, there actually is such a thing as ideology separate from that event and/or political experience and that psychologists ought to understand the meaning of ideology in order to understand future human activities as outside observers. Third, Jost seems to see this objective ideology as a unidirectional, causal mechanism for activity, a mechanism that assumes individuals act according to ideology, which eclipses the possibility that immediate ideological positions are the residue of purposeful activity. Glassman and Karno suggest that it may be better to take a pluralistic view of ideology in human action. Where ideology does exist, it is as a purposeful instrument--part of a logically based action to meet some ends-in-view--a mixture of immediate goals tied to secondary belief systems (which have been integrated to serve the material purposes of the purveyors of these ideologies). So if we are to understand ideology, we can only understand it through its use in human activity. (Copyright) 2007 APA.

  19. Pancreatitis Quality of Life Instrument: Development of a new instrument

    Directory of Open Access Journals (Sweden)

    Wahid Wassef

    2014-02-01

    Full Text Available Objectives: The goal of this project was to develop the first disease-specific instrument for the evaluation of quality of life in chronic pancreatitis. Methods: Focus groups and interview sessions were conducted, with chronic pancreatitis patients, to identify items felt to impact quality of life which were subsequently formatted into a paper-and-pencil instrument. This instrument was used to conduct an online survey by an expert panel of pancreatologists to evaluate its content validity. Finally, the modified instrument was presented to patients during precognitive testing interviews to evaluate its clarity and appropriateness. Results: In total, 10 patients were enrolled in the focus groups and interview sessions where they identified 50 items. Once redundant items were removed, the 40 remaining items were made into a paper-and-pencil instrument referred to as the Pancreatitis Quality of Life Instrument. Through the processes of content validation and precognitive testing, the number of items in the instrument was reduced to 24. Conclusions: This marks the development of the first disease-specific instrument to evaluate quality of life in chronic pancreatitis. It includes unique features not found in generic instruments (economic factors, stigma, and spiritual factors. Although this marks a giant step forward, psychometric evaluation is still needed prior to its clinical use.

  20. Industrial instrumentation principles and design

    CERN Document Server

    Padmanabhan, Tattamangalam R

    2000-01-01

    Pneumatic, hydraulic and allied instrumentation schemes have given way to electronic schemes in recent years thanks to the rapid strides in electronics and allied areas. Principles, design and applications of such state-of-the-art instrumentation schemes form the subject matter of this book. Through representative examples, the basic building blocks of instrumentation schemes are identified and each of these building blocks discussed in terms of its design and interface characteristics. The common generic schemes synthesized with such building blocks are dealt with subsequently. This forms the scope of Part I. The focus in Part II is on application. Displacement and allied instrumentation, force and allied instrumentation and process instrumentation in terms of temperature, flow, pressure level and other common process variables are dealt with separately and exhaustively. Despite the diversity in the sensor principles and characteristics and the variety in the applications and their environments, it is possib...

  1. Impact Disdrometers Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Bartholomew, Mary Jane [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2016-03-01

    To improve the quantitative description of precipitation processes in climate models, the U.S. Department of Energy’s Atmospheric Radiation Measurement (ARM) Climate Research Facility has been collecting observations of the drop size spectra of rain events since early in 2006. Impact disdrometers were the initial choice due to their reliability, ease of maintenance, and relatively low cost. Each of the two units deployed was accompanied by a nearby tipping bucket. In 2010, the tipping buckets were replaced by weighing buckets rain gauges. Five video disdrometers were subsequently purchased and are described in ARM’s VDIS Handbook.1 As of April 2011, three of the weighing bucket instruments were deployed, one was to travel with the second ARM Mobile Facility, and the fifth was a spare. Two of the video disdrometers were deployed, a third was to be deployed later in the spring of 2011, one was to travel with the second ARM Mobile Facility, and the last was a spare. Detailed descriptions of impact disdrometers and their datastreams are provided in this document.

  2. TFTR CAMAC instrumentation system

    International Nuclear Information System (INIS)

    Del Gatto, H.J.; Bradish, C.J.

    1983-01-01

    The TFTR Central Instrumentation Control and Data Acquisition (CICADA) system makes extensive use of CAMAC equipment. The system consists of eight CAMAC highways operating from eight Gould 75/32 computers. Links up to 3.5 miles in length with more than fifty CAMAC crates have been implemented and are currently in use. Data transfer along the highway is implemented in bit serial format. The link speed is run at 5MHz. The length and complexity of the link requires the reformatting of the NRZ input/output format of the L-2 crate controller. U-Port adapter modules are used to interface the modified serial highway to the L-2 controllers. The modified serial highway uses a transmission technique that requires the distribution of both Bi-Phase encoded data and a 5MHz clock. The Serial Driver interfaces to the GOULD computer through use of a High Speed Data (HSD) interface board which attaches to the computers internal bus. All transfers to and from the computer are accomplished by direct memory access (DMA). In addition to the standard CAMAC link the system also includes a Block Transfer (BT) system. This system provides an alternate path for transferring data between the computers and the CAMAC modules. The BT system is interfaced to the host computers through HSD boards and to the CAMAC crates through use of an auxiliary crate controllers

  3. Detectors for Tomorrow's Instruments

    Science.gov (United States)

    Moseley, Harvey

    2009-01-01

    Cryogenically cooled superconducting detectors have become essential tools for a wide range of measurement applications, ranging from quantum limited heterodyne detection in the millimeter range to direct searches for dark matter with superconducting phonon detectors operating at 20 mK. Superconducting detectors have several fundamental and practical advantages which have resulted in their rapid adoption by experimenters. Their excellent performance arises in part from reductions in noise resulting from their low operating temperatures, but unique superconducting properties provide a wide range of mechanisms for detection. For example, the steep dependence of resistance with temperature on the superconductor/normal transition provides a sensitive thermometer for calorimetric and bolometric applications. Parametric changes in the properties of superconducting resonators provides a mechanism for high sensitivity detection of submillimeter photons. From a practical point of view, the use of superconducting detectors has grown rapidly because many of these devices couple well to SQUID amplifiers, which are easily integrated with the detectors. These SQUID-based amplifiers and multiplexers have matured with the detectors; they are convenient to use, and have excellent noise performance. The first generation of fully integrated large scale superconducting detection systems are now being deployed. I will discuss the prospects for a new generation of instruments designed to take full advantage of the revolution in detector technology.

  4. Measurement, instrumentation, and sensors handbook

    CERN Document Server

    Eren, Halit

    2014-01-01

    The Second Edition of the bestselling Measurement, Instrumentation, and Sensors Handbook brings together all aspects of the design and implementation of measurement, instrumentation, and sensors. Reflecting the current state of the art, it describes the use of instruments and techniques for performing practical measurements in engineering, physics, chemistry, and the life sciences and discusses processing systems, automatic data acquisition, reduction and analysis, operation characteristics, accuracy, errors, calibrations, and the incorporation of standards for control purposes. Organized acco

  5. Experimenting with string musical instruments

    Science.gov (United States)

    LoPresto, Michael C.

    2012-03-01

    What follows are several investigations involving string musical instruments developed for and used in a Science of Sound & Light course. The experiments make use of a guitar, orchestral string instruments and data collection and graphing software. They are designed to provide students with concrete examples of how mathematical formulae, when used in physics, represent reality that can actually be observed, in this case, the operation of string musical instruments.

  6. Evaluating the Relational Coordination instrument

    DEFF Research Database (Denmark)

    Edwards, Kasper; Lundstrøm, Sanne Lykke

    2014-01-01

    consistency, interrater agreement and reliability, structural validity, content validity. However as relational coordination is being used as a diagnostics tool it is important to examine further if the instrument can measure changes. Indeed we need to know how precise and sensitive the instrument is when....... We distinguish between statistical and clinical significance. Statistical significance is calculated using T-test. Clinical significance is the minimal amount of change in relational coordination score that is not considered noise. Sensitivity of the instrument i.e. the ability of the instrument...

  7. Instruments to assess integrated care

    DEFF Research Database (Denmark)

    Lyngsø, Anne Marie; Godtfredsen, Nina Skavlan; Høst, Dorte

    2014-01-01

    INTRODUCTION: Although several measurement instruments have been developed to measure the level of integrated health care delivery, no standardised, validated instrument exists covering all aspects of integrated care. The purpose of this review is to identify the instruments concerning how to mea...... was prevalent. It is uncertain whether development of a single 'all-inclusive' model for assessing integrated care is desirable. We emphasise the continuing need for validated instruments embedded in theoretical contexts.......INTRODUCTION: Although several measurement instruments have been developed to measure the level of integrated health care delivery, no standardised, validated instrument exists covering all aspects of integrated care. The purpose of this review is to identify the instruments concerning how...... to measure the level of integration across health-care sectors and to assess and evaluate the organisational elements within the instruments identified. METHODS: An extensive, systematic literature review in PubMed, CINAHL, PsycINFO, Cochrane Library, Web of Science for the years 1980-2011. Selected...

  8. Atomic absorption instrument functional description

    International Nuclear Information System (INIS)

    Bystroff, R.I.; Boyle, W.G. Jr.; Barton, G.W. Jr.

    1976-01-01

    This report describes a proposed system for automating atomic absorption analysis. The system consists of two atomic absorption instruments and an automatic sampler that can be attached to either instrument. A computer program controls the sampling and gathers data. The program then uses the data to perform bookkeeping, data processing, and report writing

  9. Nuclear instrumentation evaluation and analysis

    International Nuclear Information System (INIS)

    Park, Suk Jun; Han, Sang Joon; Chung, Chong Eun; Han, Kwang Soo; Kim, Dong Hwa; Park, Byung Hae; Moon, Je Sun; Lee, Chel Kwon; Song, Ki Sang; Choi, Myung Jin; Kim, Seung Bok; Kim, Jung Bok

    1986-12-01

    This project provides the program for improving instrumentation reliability as well as developing a cost-effective preventive maintenance activity through evaluation and analysis of nuclear instrumentation concerning pilot plants, large-scale test facilities and various laboratories on KAERI site. In addition, it discusses the program for enhancing safe operations and improving facility availability through establishment of maintenance technology. (Author)

  10. A Database Management Assessment Instrument

    Science.gov (United States)

    Landry, Jeffrey P.; Pardue, J. Harold; Daigle, Roy; Longenecker, Herbert E., Jr.

    2013-01-01

    This paper describes an instrument designed for assessing learning outcomes in data management. In addition to assessment of student learning and ABET outcomes, we have also found the instrument to be effective for determining database placement of incoming information systems (IS) graduate students. Each of these three uses is discussed in this…

  11. Experimenting with String Musical Instruments

    Science.gov (United States)

    LoPresto, Michael C.

    2012-01-01

    What follows are several investigations involving string musical instruments developed for and used in a "Science of Sound & Light" course. The experiments make use of a guitar, orchestral string instruments and data collection and graphing software. They are designed to provide students with concrete examples of how mathematical formulae, when…

  12. Developing a workplace resilience instrument.

    Science.gov (United States)

    Mallak, Larry A; Yildiz, Mustafa

    2016-05-27

    Resilience benefits from the use of protective factors, as opposed to risk factors, which are associated with vulnerability. Considerable research and instrument development has been conducted in clinical settings for patients. The need existed for an instrument to be developed in a workplace setting to measure resilience of employees. This study developed and tested a resilience instrument for employees in the workplace. The research instrument was distributed to executives and nurses working in the United States in hospital settings. Five-hundred-forty completed and usable responses were obtained. The instrument contained an inventory of workplace resilience, a job stress questionnaire, and relevant demographics. The resilience items were written based on previous work by the lead author and inspired by Weick's [1] sense-making theory. A four-factor model yielded an instrument having psychometric properties showing good model fit. Twenty items were retained for the resulting Workplace Resilience Instrument (WRI). Parallel analysis was conducted with successive iterations of exploratory and confirmatory factor analyses. Respondents were classified based on their employment with either a rural or an urban hospital. Executives had significantly higher WRI scores than nurses, controlling for gender. WRI scores were positively and significantly correlated with years of experience and the Brief Job Stress Questionnaire. An instrument to measure individual resilience in the workplace (WRI) was developed. The WRI's four factors identify dimensions of workplace resilience for use in subsequent investigations: Active Problem-Solving, Team Efficacy, Confident Sense-Making, and Bricolage.

  13. Smart antennas for nuclear instruments

    International Nuclear Information System (INIS)

    Jain, Ranjan Bala; Singhi, B.M.

    2005-01-01

    The advances in the field of computer and communications are leading to the development of smart embedded nuclear instruments. These instruments have highly sophisticated signal-processing algorithms based on FPGA and ASICS, provisions of present day connectivity and user interfaces. The developments in the connectivity, standards and bus technologies have made possible to access these instruments on LAN and WAN with suitable reliability and security. To get rid of wires i.e. in order to access these instruments, without wires at any place, wireless technology has evolved and become integral part of day-to-day activities. The environment monitoring can be done remotely, if smart antennas are incorporated on these instruments

  14. How discriminating are discriminative instruments?

    Science.gov (United States)

    Hankins, Matthew

    2008-05-27

    The McMaster framework introduced by Kirshner & Guyatt is the dominant paradigm for the development of measures of health status and health-related quality of life (HRQL). The framework defines the functions of such instruments as evaluative, predictive or discriminative. Evaluative instruments are required to be sensitive to change (responsiveness), but there is no corresponding index of the degree to which discriminative instruments are sensitive to cross-sectional differences. This paper argues that indices of validity and reliability are not sufficient to demonstrate that a discriminative instrument performs its function of discriminating between individuals, and that the McMaster framework would be augmented by the addition of a separate index of discrimination. The coefficient proposed by Ferguson (Delta) is easily adapted to HRQL instruments and is a direct, non-parametric index of the degree to which an instrument distinguishes between individuals. While Delta should prove useful in the development and evaluation of discriminative instruments, further research is required to elucidate the relationship between the measurement properties of discrimination, reliability and responsiveness.

  15. How discriminating are discriminative instruments?

    Directory of Open Access Journals (Sweden)

    Hankins Matthew

    2008-05-01

    Full Text Available Abstract The McMaster framework introduced by Kirshner & Guyatt is the dominant paradigm for the development of measures of health status and health-related quality of life (HRQL. The framework defines the functions of such instruments as evaluative, predictive or discriminative. Evaluative instruments are required to be sensitive to change (responsiveness, but there is no corresponding index of the degree to which discriminative instruments are sensitive to cross-sectional differences. This paper argues that indices of validity and reliability are not sufficient to demonstrate that a discriminative instrument performs its function of discriminating between individuals, and that the McMaster framework would be augmented by the addition of a separate index of discrimination. The coefficient proposed by Ferguson (Delta is easily adapted to HRQL instruments and is a direct, non-parametric index of the degree to which an instrument distinguishes between individuals. While Delta should prove useful in the development and evaluation of discriminative instruments, further research is required to elucidate the relationship between the measurement properties of discrimination, reliability and responsiveness.

  16. Instrumentation in elementary particle physics

    Energy Technology Data Exchange (ETDEWEB)

    Fabjan, C W [European Organization for Nuclear Research, Geneva (Switzerland); Pilcher, J E [Chicago Univ., IL (United States); eds.

    1988-01-01

    The first International Committee for Future Accelerators Instrumentation School was held at the International Centre for Theoretical Physics, Trieste, Italy from 8 to 19 June 1987. The School was attended by 74 students of whom 45 were from developing countries, 10 lecturers and 9 laboratory instructors. The next generation of elementary particle physics experiments would depend vitally on new ideas in instrumentation. This is a field where creativity and imagination play a major role and large budgets are not a prerequisite. One of the unique features was the presentation of four laboratory experiments using modern techniques and instrumentation. Refs, figs and tabs.

  17. Adjustable extender for instrument module

    International Nuclear Information System (INIS)

    Sevec, J.B.; Stein, A.D.

    1975-01-01

    A blank extender module used to mount an instrument module in front of its console for repair or test purposes has been equipped with a rotatable mount and means for locking the mount at various angles of rotation for easy accessibility. The rotatable mount includes a horizontal conduit supported by bearings within the blank module. The conduit is spring-biased in a retracted position within the blank module and in this position a small gear mounted on the conduit periphery is locked by a fixed pawl. The conduit and instrument mount can be pulled into an extended position with the gear clearing the pawl to permit rotation and adjustment of the instrument

  18. Instrumentation in elementary particle physics

    International Nuclear Information System (INIS)

    Fabjan, C.W.; Pilcher, J.E.

    1988-01-01

    The first International Committee for Future Accelerators Instrumentation School was held at the International Centre for Theoretical Physics, Trieste, Italy from 8 to 19 June 1987. The School was attended by 74 students of whom 45 were from developing countries, 10 lecturers and 9 laboratory instructors. The next generation of elementary particle physics experiments would depend vitally on new ideas in instrumentation. This is a field where creativity and imagination play a major role and large budgets are not a prerequisite. One of the unique features was the presentation of four laboratory experiments using modern techniques and instrumentation. Refs, figs and tabs

  19. Traceability of radiation protection instruments

    Science.gov (United States)

    Hino, Y.; Kurosawa, T.

    2007-08-01

    Radiation protection instruments are used in daily measurement of dose and activities in workplaces and environments for safety management. The requirements for calibration certificates with traceability are increasing for these instruments to ensure the consistency and reliabilities of the measurement results. The present traceability scheme of radiation protection instruments for dose and activity measurements is described with related IEC/ISO requirements. Some examples of desirable future calibration systems with recent new technologies are also discussed to establish the traceability with reasonable costs and reliabilities.

  20. Steam 80 steam generator instrumentation

    International Nuclear Information System (INIS)

    Carson, W.H.; Harris, H.H.

    1980-01-01

    This paper describes two special instrumentation packages in an integral economizer (preheater) steam generator of one of the first System 80 plants scheduled to go into commercial operation. The purpose of the instrumentation is to obtain accurate operating information from regions of the secondary side of the steam generator inaccessible to normal plant instrumentation. In addition to verification of the System 80 steam generator design predictions, the data obtained will assist in verification of steam generator thermal/hydraulic computer codes developed for generic use in the industry

  1. Commissioning Instrument for the GTC

    Science.gov (United States)

    Cuevas, S.; Sánchez, B.; Bringas, V.; Espejo, C.; Flores, R.; Chapa, O.; Lara, G.; Chavolla, A.; Anguiano, G.; Arciniega, S.; Dorantes, A.; González, J. L.; Montoya, J. M.; Toral, R.; Hernández, H.; Nava, R.; Devaney, N.; Castro, J.; Cavaller-Marqués, L.

    2005-12-01

    During the GTC integration phase, the Commissioning Instrument (CI) will be a diagnostic tool for performance verification. The CI features four operation modes: imaging, pupil imaging, Curvature WFS, and high resolution Shack-Hartmann WFS. This instrument was built by the Instituto de Astronomía UNAM and the Centro de Ingeniería y Desarrollo Industrial (CIDESI) under GRANTECAN contract after a public bid. In this paper we made a general instrument overview and we show some of the performance final results obtained when the Factory Acceptance tests previous to its transport to La Palma.

  2. Instrumentation for Air Pollution Monitoring

    Science.gov (United States)

    Hollowell, Craig D.; McLaughlin, Ralph D.

    1973-01-01

    Describes the techniques which form the basis of current commercial instrumentation for monitoring five major gaseous atmospheric pollutants (sulfur dioxide, oxides of nitrogen, oxidants, carbon monoxide, and hydrocarbons). (JR)

  3. Survey of instruments for micrometeorology

    National Research Council Canada - National Science Library

    Monteith, John Lennox

    1972-01-01

    ... have been developed for micrometeorological measurements. Many of these instruments can be used by ecologists to measure and define the environment of plants and animals and to explore the ways in which organisms modify the environment they are exposed...

  4. Digital instrumentation for retrofit applications

    International Nuclear Information System (INIS)

    Dennis, U.E.

    1986-01-01

    There can be many reasons for applying retrofit designs to existing power plants. Whatever the reasons, care in planning and instrument design will be required in order to derive the full benefits afforded by today's technology. Specifically, the availability of microprocessors and their related integrated circuits make possible capabilities, accuracies, reliabilities, maintainability and user interfaces not achievable when original equipment was designed. Some of the motives for the replacement of current instrumentation are examined and the various benefits and pitfalls of applying present day microprocessor technology to new designs are discussed. From this, a set of design objectives can be formulated that can best take advantage of modern technology. General Electric's design solution, a family of instruments called NUMAC (Nuclear Measurement, Analysis and Control) is described, followed by descriptions of instruments currently in production and those contemplated for design in the near future

  5. Economic instruments for environmental mitigation

    International Nuclear Information System (INIS)

    Wilkinson, A.

    1995-01-01

    A joint International Chamber of Commerce (ICC)/World Energy Council (WEC) Working Group has been studying a range of policy instruments which are being used or considered for use to address the question of ever increasing energy demand versus environmental protection, and pollution reduction. Economic instruments for such environmental protection include direct regulation, market-based instruments, and voluntary approaches. No single policy or device was likely to suffice in addressing the diversity of environmental problems currently faced. Altering energy prices must be seen in a social context, but some direct regulation may also be inevitable. Generally economic instruments of change were preferred as these were viewed as more flexible and cost-effective. (UK)

  6. PEP instrumentation and control system

    Energy Technology Data Exchange (ETDEWEB)

    Melen, R.

    1980-06-01

    This paper describes the operating characteristics of the primary components that form the PEP Instrumentation and Control System. Descriptions are provided for the computer control system, beam monitors, and other support systems.

  7. Technical Training seminar: Texas Instruments

    CERN Multimedia

    2006-01-01

    Monday 6 November TECHNICAL TRAINING SEMINAR 14:00 to 17:30 - Training Centre Auditorium (bldg. 593) Texas Instruments Technical Seminar Michael Scholtholt, Field Application Engineer / TEXAS INSTRUMENTS (US, D, CH) POWER - A short approach to Texas Instruments power products Voltage mode vs. current mode control Differentiating DC/DC converters by analyzing control and compensation schemes: line / load regulation, transient response, BOM, board space, ease-of-use Introduction to the SWIFT software FPGA + CPLD power solutions WIRELESS / CHIPCON Decision criteria when choosing a RF platform Introduction to Texas Instruments wireless products: standardized platforms proprietary platforms ( 2.4 GHz / sub 1 GHz) development tools Antenna design: example for 2.4 GHz questions, discussion Industrial partners: Robert Medioni, François Caloz / Spoerle Electronic, CH-1440 Montagny (VD), Switzerland Phone: +41 24 447 0137, email: RMedioni@spoerle.com, http://www.spoerle.com Language: English. Free s...

  8. PEP instrumentation and control system

    International Nuclear Information System (INIS)

    Melen, R.

    1980-06-01

    This paper describes the operating characteristics of the primary components that form the PEP Instrumentation and Control System. Descriptions are provided for the computer control system, beam monitors, and other support systems

  9. Intelligent instrumentation principles and applications

    CERN Document Server

    Bhuyan, Manabendra

    2011-01-01

    With the advent of microprocessors and digital-processing technologies as catalyst, classical sensors capable of simple signal conditioning operations have evolved rapidly to take on higher and more specialized functions including validation, compensation, and classification. This new category of sensor expands the scope of incorporating intelligence into instrumentation systems, yet with such rapid changes, there has developed no universal standard for design, definition, or requirement with which to unify intelligent instrumentation. Explaining the underlying design methodologies of intelligent instrumentation, Intelligent Instrumentation: Principles and Applications provides a comprehensive and authoritative resource on the scientific foundations from which to coordinate and advance the field. Employing a textbook-like language, this book translates methodologies to more than 80 numerical examples, and provides applications in 14 case studies for a complete and working understanding of the material. Beginn...

  10. A Finescale Lagrangian Instrument System

    National Research Council Canada - National Science Library

    Toole, John

    2003-01-01

    ... from conventional, bottom-anchored moorings. An initial trial of the concept targeting the upper ocean was carried out off Bermuda in November 2001 with an instrument profiling between 12 and 28O-m depth...

  11. Instrumental development and data processing

    International Nuclear Information System (INIS)

    Franzen, J.

    1978-01-01

    A review of recent developments in mass spectrometry instrumentation is presented under the following headings: introduction (scope of mass spectrometry compared with neighbouring fields); ion sources and ionization techniques; spectrometers (instrumental developments); measuring procedures; coupling techniques; data systems; conclusions (that mass spectrometry should have a broader basis and that there would be mutual profit from a better penetration of mass spectrometry into fields of routine application). (U.K.)

  12. MITS instrumentation error analysis report

    International Nuclear Information System (INIS)

    Nelson, D.W.; Hillon, D.D.

    1980-01-01

    The MITS (Machine Interface Test System) installation consists of three types of process monitoring and control instrumentation: flow, pressure, and temperature. An effort has been made to assess the various instruments used and assign a value to the accuracy that can be expected. Efforts were also made to analyze the calibration and installation procedures to be used and determine how these might effect the system accuracy

  13. Notes on instrumentation and control

    CERN Document Server

    Roy, G J

    2013-01-01

    Notes on Instrumentation and Control presents topics on pressure (i.e., U-tube manometers and elastic type gauges), temperature (i.e. glass thermometer, bi-metallic strip thermometer, filled system thermometer, vapor pressure thermometer), level, and flow measuring devices. The book describes other miscellaneous instruments, signal transmitting devices, supply and control systems, and monitoring systems. The theory of automatic control and semi-conductor devices are also considered. Marine engineers will find the book useful.

  14. Nucleonic instruments from VUPJT Tesla

    International Nuclear Information System (INIS)

    Smola, J.

    1986-01-01

    The instruments currently produced by Tesla Premysleni are listed and briefly characterized. They include a low level alpha-beta counter, an automatic low level alpha-beta counter, detection units for environmental sample counting, instruments for measuring specific activity of liquids and radon concentration in water, a radioactive aerosol meter, dose ratemeters, portable alpha-beta indicators for surface contamintion monitoring, neutron monitors, single-, two- and three-channel spectrometric units. (M.D.)

  15. Sulfur Dioxide Analyzer Instrument Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Springston, Stephen R. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    2016-05-01

    The Sulfur Dioxide Analyzer measures sulfur dioxide based on absorbance of UV light at one wavelength by SO2 molecules which then decay to a lower energy state by emitting UV light at a longer wavelength. Specifically, SO2 + hυ1 →SO2 *→SO2 + hυ2 The emitted light is proportional to the concentration of SO2 in the optical cell. External communication with the analyzer is available through an Ethernet port configured through the instrument network of the AOS systems. The Model 43i-TLE is part of the i-series of Thermo Scientific instruments. The i-series instruments are designed to interface with external computers through the proprietary Thermo Scientific iPort Software. However, this software is somewhat cumbersome and inflexible. Brookhaven National Laboratory (BNL) has written an interface program in National Instruments LabView that both controls the Model 43i-TLE Analyzer AND queries the unit for all measurement and housekeeping data. The LabView vi (the software program written by BNL) ingests all raw data from the instrument and outputs raw data files in a uniform data format similar to other instruments in the AOS and described more fully in Section 6.0 below.

  16. Isotope-equipped measuring instruments

    International Nuclear Information System (INIS)

    Miyagawa, Kazuo; Amano, Hiroshi

    1980-01-01

    In the steel industry, though the investment in isotope-equipped measuring instruments is small as compared with that in machinery, they play important role in the moisture measurement in sintering and blast furnaces, the thickness measurement in rolling process and others in automatic control systems. The economic aspect of the isotope-equipped measuring instruments is described on the basis of the practices in Kimitsu Works of Nippon Steel Corporation: distribution of such instruments, evaluation of economic effects, usefulness evaluation in view of raising the accuracy, and usefulness evaluation viewed from the failure of the isotope instruments. The evaluation of economic effects was made under the premise that the isotope-equipped measuring instruments are not employed. Then, the effects of raising the accuracy are evaluated for a γ-ray plate thickness gauge and a neutron moisture gauge for coke in a blast furnace. Finally, the usefulness was evaluated, assuming possible failure of the isotope-equipped measuring instruments. (J.P.N.)

  17. On Representative Spaceflight Instrument and Associated Instrument Sensor Web Framework

    Science.gov (United States)

    Kizhner, Semion; Patel, Umeshkumar; Vootukuru, Meg

    2007-01-01

    Sensor Web-based adaptation and sharing of space flight mission resources, including those of the Space-Ground and Control-User communication segment, could greatly benefit from utilization of heritage Internet Protocols and devices applied for Spaceflight (SpaceIP). This had been successfully demonstrated by a few recent spaceflight experiments. However, while terrestrial applications of Internet protocols are well developed and understood (mostly due to billions of dollars in investments by the military and industry), the spaceflight application of Internet protocols is still in its infancy. Progress in the developments of SpaceIP-enabled instrument components will largely determine the SpaceIP utilization of those investments and acceptance in years to come. Likewise SpaceIP, the development of commercial real-time and instrument colocated computational resources, data compression and storage, can be enabled on-board a spacecraft and, in turn, support a powerful application to Sensor Web-based design of a spaceflight instrument. Sensor Web-enabled reconfiguration and adaptation of structures for hardware resources and information systems will commence application of Field Programmable Arrays (FPGA) and other aerospace programmable logic devices for what this technology was intended. These are a few obvious potential benefits of Sensor Web technologies for spaceflight applications. However, they are still waiting to be explored. This is because there is a need for a new approach to spaceflight instrumentation in order to make these mature sensor web technologies applicable for spaceflight. In this paper we present an approach in developing related and enabling spaceflight instrument-level technologies based on the new concept of a representative spaceflight Instrument Sensor Web (ISW).

  18. Musical Sound, Instruments, and Equipment

    Science.gov (United States)

    Photinos, Panos

    2017-12-01

    'Musical Sound, Instruments, and Equipment' offers a basic understanding of sound, musical instruments and music equipment, geared towards a general audience and non-science majors. The book begins with an introduction of the fundamental properties of sound waves, and the perception of the characteristics of sound. The relation between intensity and loudness, and the relation between frequency and pitch are discussed. The basics of propagation of sound waves, and the interaction of sound waves with objects and structures of various sizes are introduced. Standing waves, harmonics and resonance are explained in simple terms, using graphics that provide a visual understanding. The development is focused on musical instruments and acoustics. The construction of musical scales and the frequency relations are reviewed and applied in the description of musical instruments. The frequency spectrum of selected instruments is explored using freely available sound analysis software. Sound amplification and sound recording, including analog and digital approaches, are discussed in two separate chapters. The book concludes with a chapter on acoustics, the physical factors that affect the quality of the music experience, and practical ways to improve the acoustics at home or small recording studios. A brief technical section is provided at the end of each chapter, where the interested reader can find the relevant physics and sample calculations. These quantitative sections can be skipped without affecting the comprehension of the basic material. Questions are provided to test the reader's understanding of the material. Answers are given in the appendix.

  19. Apical instrumentation in endodontic therapy

    Directory of Open Access Journals (Sweden)

    Kurniasri Darliana

    2007-07-01

    Full Text Available Cleaning and shaping of the root canal as the foundation for successful endodontic therapy. Cleaning of the root canal as the removal of all the contents of the root canal systems before and during shaping. Mechanical cleaning as the most important part of the root canal therapy. Instrumentation of the apical region has long been considered to be an essential component in the cleaning and shaping process. The apical area as the critical zone for instrumentation. The apical portion of the root canal system can retain microorganisms that could potentially cause periradicular inflammation. The nickel-titanium rotary instrumentation system to facilitate the cleaning and shaping process. Larger instrumentation sizes not only allow proper irrigation but also significantly decrease remaining bacteria in the canal system. How the larger apical sizes preparation must be achieved to clinical success. This paper will describe the major factors impacting the selection of final apical size, the factors are the anatomy of the apical constriction, root canal diameter, apical instrumentation, and bacteria in dentin tubuli.

  20. 31 CFR 596.307 - Monetary instruments.

    Science.gov (United States)

    2010-07-01

    ... FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY TERRORISM LIST GOVERNMENTS SANCTIONS REGULATIONS General Definitions § 596.307 Monetary instruments. The term monetary instruments shall have the meaning...

  1. Refabricated and instrumented fuel rods

    International Nuclear Information System (INIS)

    Silberstein, K.

    2005-01-01

    Nuclear Fuel for power reactors capabilities evaluation is strongly based on the intimate knowledge of its behaviour under irradiation. This knowledge can be acquired from refabricated and instrumented fuel rods irradiated at different levels in commercial reactors. This paper presents the development and qualification of a new technique called RECTO related to a double-instrumented rod re-fabrication process developed by CEA/LECA hot laboratory facility at CADARACHE. The technique development includes manufacturing of the properly dimensioned cavity in the fuel pellet stack to house the thermocouple and the use of a newly designed pressure transducer. An analytic irradiation of such a double-instrumented fuel rod will be performed in OSIRIS test reactor starting October 2004. (Author)

  2. HTGR Measurements and Instrumentation Systems

    International Nuclear Information System (INIS)

    Ball, Sydney J.; Holcomb, David Eugene; Cetiner, Mustafa Sacit

    2012-01-01

    This report provides an integrated overview of measurements and instrumentation for near-term future high-temperature gas-cooled reactors (HTGRs). Instrumentation technology has undergone revolutionary improvements since the last HTGR was constructed in the United States. This report briefly describes the measurement and communications needs of HTGRs for normal operations, maintenance and inspection, fuel fabrication, and accident response. The report includes a description of modern communications technologies and also provides a potential instrumentation communications architecture designed for deployment at an HTGR. A principal focus for the report is describing new and emerging measurement technologies with high potential to improve operations, maintenance, and accident response for the next generation of HTGRs, known as modular HTGRs, which are designed with passive safety features. Special focus is devoted toward describing the failure modes of the measurement technologies and assessing the technology maturity.

  3. Seismic Instrumentation Placement Recommendations Report

    International Nuclear Information System (INIS)

    Kennedy, W.N.

    1998-01-01

    DOE Order 420.1, ''Facility Safety'', requires that facilities or sites with hazardous materials be provided with instrumentation or other means to detect and record the occurrences and severity of seismic events. These requirements assure that necessary records are available after an earthquake for evaluation purposes and to supplement other data to justify a facility restart or curtailing plant operations after an earthquake. This report documents the basis for the selection of Savannah River Site areas and existing facilities to be instrumented. The need to install instrumentation in new facilities such as the Actinide Packaging and Storage Facility, Commercial Light Water Reactor Tritium Extraction Facility and the Accelerator Production of Tritium Facility will be assessed separately

  4. Introduction to instrumentation and measurements

    CERN Document Server

    Northrop, Robert B

    2014-01-01

    Weighing in on the growth of innovative technologies, the adoption of new standards, and the lack of educational development as it relates to current and emerging applications, the third edition of Introduction to Instrumentation and Measurements uses the authors' 40 years of teaching experience to expound on the theory, science, and art of modern instrumentation and measurements (I&M). What's New in This Edition: This edition includes material on modern integrated circuit (IC) and photonic sensors, micro-electro-mechanical (MEM) and nano-electro-mechanical (NEM) sensors, chemical and radiation sensors, signal conditioning, noise, data interfaces, and basic digital signal processing (DSP), and upgrades every chapter with the latest advancements. It contains new material on the designs of micro-electro-mechanical (MEMS) sensors, adds two new chapters on wireless instrumentation and microsensors, and incorporates extensive biomedical examples and problems. Containing 13 chapters, this third edition: Describ...

  5. Technical presentation - KEITHLEY Instruments - CANCELLED

    CERN Multimedia

    FI Department

    2009-01-01

    10 March 2009 13:30 – 15:30, Council Chamber, Bldg. 503 Keithley markets highly accurate instruments and data acquisition products, as well as complete system solutions for high-volume production and assembly testing. Keithley Instruments, Inc. designs, develops, manufactures and markets complex electronic instruments and systems geared to the specialized needs of electronics manufacturers for high-performance production testing, process monitoring, product development and research. Products and Services: Digital Multimeters and Data Acquisition Systems Current / Voltage Source and Measure Products Low Current / High Resistance Measurement Products Function/Pulse/Arbitrary/Pattern Generators Low Voltage/Low Resistance Measurement Products RF Spectrum Analyzer / RF Signal Generator / RF Switching Semiconductor Device Characterization Program: Topic 1: Welcome and short overview of new Products SMU 26XXA / ARB Generator 3390 / DMM 3706 / E-Meter 6517B Topic 2a: Te...

  6. Safeguards instrumentation: past, present, future

    International Nuclear Information System (INIS)

    Higinbotham, W.A.

    1982-01-01

    Instruments are essential for accounting, for surveillance and for protection of nuclear materials. The development and application of such instrumentation is reviewed, with special attention to international safeguards applications. Active and passive nondestructive assay techniques are some 25 years of age. The important advances have been in learning how to use them effectively for specific applications, accompanied by major advances in radiation detectors, electronics, and, more recently, in mini-computers. The progress in seals has been disappointingly slow. Surveillance cameras have been widely used for many applications other than safeguards. The revolution in TV technology will have important implications. More sophisticated containment/surveillance equipment is being developed but has yet to be exploited. On the basis of this history, some expectations for instrumentation in the near future are presented

  7. Solution assay instrument operations manual

    International Nuclear Information System (INIS)

    Li, T.K.; Marks, T.; Parker, J.L.

    1983-09-01

    An at-line solution assay instrument (SAI) has been developed and installed in a plutonium purification and americium recovery process area in the Los Alamos Plutonium Processing Facility. The instrument was designed for accurate, timely, and simultaneous nondestructive analysis of plutonium and americium in process solutions that have a wide range of concentrations and americium/plutonium ratios and for routine operation by process technicians who lack instrumentation background. The SAI, based on transmission-corrected, high-resolution gamma-ray spectroscopy, has two measurement stations attached to a single multichannel analyzer/computer system. To ensure the quality of assay results, the SAI has an internal measurement control program, which requires daily and weekly check runs and monitors key aspects of all assay runs. For a 25-ml sample, the assay precision is 5 g/l within a 2000-s count time

  8. Recent developments in nuclear instruments

    International Nuclear Information System (INIS)

    Vaidya, P.P.

    2004-01-01

    Full text : Nuclear Instrumentation is a field of vital importance for DAE. It has important applications in many areas of interest such as Reactor Monitoring and control, Accelerator based research, Laser and nuclear physics experiments, Health and environmental monitoring, Astrophysics experiments etc. It is a specialized field involving expertise in detection of radioactivity down to the level of few events per minute as well as processing and analysis of signals which can be as small as few hundred micro volts embedded in noise. Some applications involve digitizing and processing these signals with 0.001% accuracy and timing accuracies of a fraction of nano sec. Rapid developments in semiconductor related technologies have influenced the field of nuclear instrumentation. Development of FPGA's and ASIC's have made it possible to develop miniaturized smart and portable instruments for field applications. Advancements in field of computers, communications and various field buses have been successfully utilized for smart, portable and DSP based instrumentation. Smart sensor with detector and front-end electronics on a single silicon chip is now a reality. These instruments are also made intelligent by addition of fuzzy logic, artificial neural networks and expert systems. Electronics Division of BARC has made significant contribution to the field of nuclear instrumentation to achieve self-reliance in this area. This has also led to development of several new methods, which have been published in international journals and appreciated worldwide. As a step towards achieving complete self-reliance a programme for development of FPGA's, HMC's and ASIC's has been undertaken and is being followed with special emphasis. This also includes development of detector and front- end electronics on a single chip. This talk brings out details of these developments and describes the 'state of art' work done in India

  9. Instrumentation for tropospheric aerosol characterization

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Z.; Young, S.E.; Becker, C.H.; Coggiola, M.J. [SRI International, Menlo Park, CA (United States); Wollnik, H. [Giessen Univ. (Germany)

    1997-12-31

    A new instrument has been developed that determines the abundance, size distribution, and chemical composition of tropospheric and lower stratospheric aerosols with diameters down to 0.2 {mu}m. In addition to aerosol characterization, the instrument also monitors the chemical composition of the ambient gas. More than 25.000 aerosol particle mass spectra were recorded during the NASA-sponsored Subsonic Aircraft: Contrail and Cloud Effects Special Study (SUCCESS) field program using NASA`s DC-8 research aircraft. (author) 7 refs.

  10. Instrumentation for tropospheric aerosol characterization

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Z; Young, S E; Becker, C H; Coggiola, M J [SRI International, Menlo Park, CA (United States); Wollnik, H [Giessen Univ. (Germany)

    1998-12-31

    A new instrument has been developed that determines the abundance, size distribution, and chemical composition of tropospheric and lower stratospheric aerosols with diameters down to 0.2 {mu}m. In addition to aerosol characterization, the instrument also monitors the chemical composition of the ambient gas. More than 25.000 aerosol particle mass spectra were recorded during the NASA-sponsored Subsonic Aircraft: Contrail and Cloud Effects Special Study (SUCCESS) field program using NASA`s DC-8 research aircraft. (author) 7 refs.

  11. Neutron-multiplication measurement instrument

    Energy Technology Data Exchange (ETDEWEB)

    Nixon, K.V.; Dowdy, E.J.; France, S.W.; Millegan, D.R.; Robba, A.A.

    1982-01-01

    The Advanced Nuclear Technology Group of the Los Alamos National Laboratory is now using intelligent data-acquisition and analysis instrumentation for determining the multiplication of nuclear material. Earlier instrumentation, such as the large NIM-crate systems, depended on house power and required additional computation to determine multiplication or to estimate error. The portable, battery-powered multiplication measurement unit, with advanced computational power, acquires data, calculates multiplication, and completes error analysis automatically. Thus, the multiplication is determined easily and an available error estimate enables the user to judge the significance of results.

  12. Neutron-multiplication measurement instrument

    International Nuclear Information System (INIS)

    Nixon, K.V.; Dowdy, E.J.; France, S.W.; Millegan, D.R.; Robba, A.A.

    1982-01-01

    The Advanced Nuclear Technology Group of the Los Alamos National Laboratory is now using intelligent data-acquisition and analysis instrumentation for determining the multiplication of nuclear material. Earlier instrumentation, such as the large NIM-crate systems, depended on house power and required additional computation to determine multiplication or to estimate error. The portable, battery-powered multiplication measurement unit, with advanced computational power, acquires data, calculates multiplication, and completes error analysis automatically. Thus, the multiplication is determined easily and an available error estimate enables the user to judge the significance of results

  13. Practical course on reactor instrumentation

    International Nuclear Information System (INIS)

    Boeck, H.; Villa, M.

    2004-06-01

    This course is based on the description of the instrumentation of the TRIGA-reactor Vienna, which is used for training research and isotope production. It comprises the following chapters: 1. instrumentation, 2. calibration of the nuclear channels, 3. rod drop time of the control rods, 4. neutron flux density measurements using compensated ionization, 5. neutron flux density measurement with fission chambers (FC), 6. neutron flux density measurement with self-powered neutron detectors (SPND), 7. pressurized water reactor simulator, 8. verification of the radiation level during reactor operation. There is one appendix about neutron-sensitive thermocouples. (nevyjel)

  14. Formation Flying and Deformable Instruments

    International Nuclear Information System (INIS)

    Rio, Yvon

    2009-01-01

    Astronomers have always attempted to build very stable instruments. They fight all that can cause mechanical deformation or image motion. This has led to well established technologies (autoguide, active optics, thermal control, tip/tilt correction), as well as observing methods based on the use of controlled motion (scanning, micro scanning, shift and add, chopping and nodding). Formation flying disturbs this practice. It is neither possible to reduce the relative motion to very small amplitudes, nor to control it at will. Some impacts on Simbol-X instrument design, and operation are presented.

  15. Formation Flying and Deformable Instruments

    Science.gov (United States)

    Rio, Yvon

    2009-05-01

    Astronomers have always attempted to build very stable instruments. They fight all that can cause mechanical deformation or image motion. This has led to well established technologies (autoguide, active optics, thermal control, tip/tilt correction), as well as observing methods based on the use of controlled motion (scanning, micro scanning, shift and add, chopping and nodding). Formation flying disturbs this practice. It is neither possible to reduce the relative motion to very small amplitudes, nor to control it at will. Some impacts on Simbol-X instrument design, and operation are presented.

  16. Neutron beam instruments at Harwell

    International Nuclear Information System (INIS)

    Baston, A.H.; Harris, D.H.C.

    1978-11-01

    A list and brief descriptions are given of the neutron beam facilities for U.K. scientists at Harwell and in academic institutions, available under an agreement between the Science Research Council and AERE (Harwell). The list falls under the following headings: reactor instruments (single crystal diffractometers, powder diffractometers, triple axis spectrometers, time-of-flight cold neutron twin rotor spectrometer, beryllium filter spectrometer, MARX spectrometer, Harwell small-angle scattering spectrometer); LINAC instruments (total scattering spectrometer, back scattering spectrometer, active sample spectrometer, inelastic rotor spectrometer, constant Q spectrometer); ancillary equipment (cryostats, superconducting magnets, electromagnets, furnaces). (U.K.)

  17. An introduction to biomedical instrumentation

    CERN Document Server

    Dewhurst, D J

    1976-01-01

    An Introduction to Biomedical Instrumentation presents a course of study and applications covering the basic principles of medical and biological instrumentation, as well as the typical features of its design and construction. The book aims to aid not only the cognitive domain of the readers, but also their psychomotor domain as well. Aside from the seminar topics provided, which are divided into 27 chapters, the book complements these topics with practical applications of the discussions. Figures and mathematical formulas are also given. Major topics discussed include the construction, handli

  18. New instruments for radiation protection

    International Nuclear Information System (INIS)

    Bartos, D.; Ciobanu, M.; Constantin, F.; Petcu, M.; Plostinaru, V.D.; Rusu, Al.; Lupu, A.C.; Lupu, F.

    2003-01-01

    Though a century old, the radiation protection is actual by its purpose: a dose as low as reasonable achievable is to be received either by involved professionals or population. This threshold is dependent on the technical progress. Some major developments like surface mounted device technology, consumer almost ideal operational amplifiers, microcontrollers and the news signal digital processing techniques, offer the opportunity to design improved instruments for radioprotection. To put in a light portable instrument both the whole measuring system and the 'intelligence' - a microcontroller and the associated software - are the main ideas applied by the authors. The result is presented: a family of eight members, at least, based on two parents. (authors)

  19. Advances in control and instrumentation

    International Nuclear Information System (INIS)

    Surendar, Ch.

    1994-01-01

    Control and instrumentation systems have seen significant changes from pneumatic to electronic with the advent of transistors and integrated circuits. Miniaturization was realised. With the introduction of microprocessors there has been a revolutionary change in the approach in instrumentation and control systems in the areas of sensors, data acquisition/transmission, processing for control, and presentation of the information to the operator. An effort is made to give some insight into these areas, with some idea of the advantages to which these systems are being put to use in the nuclear facilities, particularly nuclear power reactors. (author)

  20. Instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    None

    1973-07-01

    Developments discussed include a transistorized- power supply for the Beckman DU spectrophotometer, a master clock pulse generator, a modular printing unit, a flash photolysis setup, a glove box assembly for a Perkin-Elmer infrared spectrophotometer, and a Faraday balance for measuring the magnetic susceptibilities of actinide compounds. (WHK)

  1. Meteorological instrumentation for nuclear facilities

    International Nuclear Information System (INIS)

    Costa, A.C.L. da.

    1983-01-01

    The main requirements of regulatory agencies, concerning the meteorological instrumentation needed for the licensing of nuclear facilities are discussed. A description is made of the operational principles of sensors for the various meteorological parameters and associated electronic systems. An analysis of the problems associated with grounding of a typical meteorological station is presented. (Author) [pt

  2. Loyaliteitsprogramma's: zinvol CRM-instrument?

    NARCIS (Netherlands)

    Leenheer, J.

    2006-01-01

    Loyalty programs have been widely adopted by companies and their customers. A loyalty program is a relational marketing instrument that aims to enhance customer loyalty. However, skepticism exists about the implementation and effectiveness of loyalty programs. This paper studies for whom, when and

  3. Literature Review of Multicultural Instrumentation

    Science.gov (United States)

    Sarraj, Huda; Carter, Stacy; Burley, Hansel

    2015-01-01

    Demographic changes at the national level emphasize a critical need for multicultural education to be included as part of undergraduate education. This critical review of the literature examines 10 multicultural instruments that are suitable for use in K-12 or higher education institutions. This is a novel literature review in that it is the first…

  4. Meteorological instrumentation for nuclear installations

    International Nuclear Information System (INIS)

    Costa, A.C.L. da.

    1983-01-01

    The main requirements of regulatory agencies, concerning the meteorological instrumentation needed for the licensing of nuclear facilities are discussed. A description is made of the operational principles of sensors for the various meteorological parameters and associated electronic systems. Finally, it is presented an analysis of the problems associated with grounding of a typical meteorological station. (Author) [pt

  5. Mobile Instruments Measure Atmospheric Pollutants

    Science.gov (United States)

    2009-01-01

    As a part of NASA's active research of the Earth s atmosphere, which has included missions such as the Atmospheric Laboratory of Applications and Science (ATLAS, launched in 1992) and the Total Ozone Mapping Spectrometer (TOMS, launched on the Earth Probe satellite in 1996), the Agency also performs ground-based air pollution research. The ability to measure trace amounts of airborne pollutants precisely and quickly is important for determining natural patterns and human effects on global warming and air pollution, but until recent advances in field-grade spectroscopic instrumentation, this rapid, accurate data collection was limited and extremely difficult. In order to understand causes of climate change and airborne pollution, NASA has supported the development of compact, low power, rapid response instruments operating in the mid-infrared "molecular fingerprint" portion of the electromagnetic spectrum. These instruments, which measure atmospheric trace gases and airborne particles, can be deployed in mobile laboratories - customized ground vehicles, typically - to map distributions of pollutants in real time. The instruments must be rugged enough to operate rapidly and accurately, despite frequent jostling that can misalign, damage, or disconnect sensitive components. By measuring quickly while moving through an environment, a mobile laboratory can correlate data and geographic points, revealing patterns in the environment s pollutants. Rapid pollutant measurements also enable direct determination of pollutant sources and sinks (mechanisms that remove greenhouse gases and pollutants), providing information critical to understanding and managing atmospheric greenhouse gas and air pollutant concentrations.

  6. Market-based Economic Instruments

    DEFF Research Database (Denmark)

    Klemmensen, Børge

    2007-01-01

    Grundkategorien her er markedet som den optimale allokeringsmekanisme for de belastninger, som de økonomiske instrumenter / miljøskatterne påfører. Det mest omfattende og spektakulære eksempel på markedet som allokatorer af skatter er EU's børs for forureningstilladelser, dvs reelt CO-2 beskatnin...

  7. Alternative instruments for the CAP?

    NARCIS (Netherlands)

    Silvis, H.J.; Rijswick, van C.W.J.; Bont, de C.J.A.M.

    2001-01-01

    With parallel negotiations taking place on enlargement of the EU and a new WTO agreement, EU's Common Agricultural Policy is facing further reforms. This report addresses the issue of whether any alternatives can be found for the instruments of this policy, and looks at decoupled payments, a net

  8. Management system of instrument database

    International Nuclear Information System (INIS)

    Zhang Xin

    1997-01-01

    The author introduces a management system of instrument database. This system has been developed using with Foxpro on network. The system has some characters such as clear structure, easy operation, flexible and convenient query, as well as the data safety and reliability

  9. Maintenance of nuclear medicine instruments

    Energy Technology Data Exchange (ETDEWEB)

    Ambro, P

    1993-12-31

    Maintenance of instruments is generally of two kinds: (a) corrective maintenance, on a non-scheduled basis, to restore equipment to a functional status by repairs; (b) preventive maintenance, to keep equipment in a specified functional condition by providing systematic inspection, quality control, detection and correction of early malfunctions. Most of the instruments used in nuclear medicine are rather complex systems built from mechanical, electrical and electronic parts. Any one of these components is liable to fail at some time or other. Repair could be done only by a specialist who is able to evaluate the condition of the various parts ranging from cables to connectors, from scintillators to photomultipliers, from microprocessors to microswitches. The knowledge of the intricacies of the various electronic components required for their repairs is quite wide and varied. The electronics industry turns out more and more multi-purpose chips which can carry out the functions of many parts used in the instruments of the earlier generation. This provides protection against unauthorized copying of the circuits but it serves another purpose as well of inhibiting repairs by non-factory personnel. These trends of the instrument design should be taken into consideration when a policy has to be developed for the repairs of the hospital based equipment 1 fig., 1 tab

  10. Maintenance of nuclear medicine instruments

    International Nuclear Information System (INIS)

    Ambro, P.

    1992-01-01

    Maintenance of instruments is generally of two kinds: (a) corrective maintenance, on a non-scheduled basis, to restore equipment to a functional status by repairs; (b) preventive maintenance, to keep equipment in a specified functional condition by providing systematic inspection, quality control, detection and correction of early malfunctions. Most of the instruments used in nuclear medicine are rather complex systems built from mechanical, electrical and electronic parts. Any one of these components is liable to fail at some time or other. Repair could be done only by a specialist who is able to evaluate the condition of the various parts ranging from cables to connectors, from scintillators to photomultipliers, from microprocessors to microswitches. The knowledge of the intricacies of the various electronic components required for their repairs is quite wide and varied. The electronics industry turns out more and more multi-purpose chips which can carry out the functions of many parts used in the instruments of the earlier generation. This provides protection against unauthorized copying of the circuits but it serves another purpose as well of inhibiting repairs by non-factory personnel. These trends of the instrument design should be taken into consideration when a policy has to be developed for the repairs of the hospital based equipment

  11. A portable luminescence dating instrument

    DEFF Research Database (Denmark)

    Kook, M.H.; Murray, A.S.; Lapp, Torben

    2011-01-01

    We describe a portable luminescence reader suitable for use in remote localities in the field. The instrument weighs about 8kg and is based around a 30mm bialkali photomultiplier detecting signals through a glass filter centered on 340nm. Stimulation is by 470nm blue LEDs (24W in total) operating...

  12. [Organising an instrumental elective abortion].

    Science.gov (United States)

    Brûlé, Annie

    2015-12-01

    Family planning centres are structures designed to receive and care for women requesting elective abortions. Here the specially trained, dedicated teams offer personalised care. The instrumental elective abortion is prepared in the same way as a surgical procedure and is subject to the same monitoring. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  13. Experimenting with Brass Musical Instruments.

    Science.gov (United States)

    LoPresto, Michael C.

    2003-01-01

    Describes experiments to address the properties of brass musical instruments that can be used to demonstrate sound in any level physics course. The experiments demonstrate in a quantitative fashion the effects of the mouthpiece and bell on the frequencies of sound waves and thus the musical pitches produced. (Author/NB)

  14. A Musical instrument in MEMS

    NARCIS (Netherlands)

    Engelen, Johannes Bernardus Charles; de Boer, Hans L.; de Boer, H.; Beekman, J.G.; Been, A.J.; Folkertsma, Gerrit Adriaan; Folkertsma, G.A.; Fortgens, L.; de Graaf, D.; Vocke, S.; Woldering, L.A.; Abelmann, Leon; Elwenspoek, Michael Curt

    In this work we describe a MEMS instrument that resonates at audible frequencies, and with which music can be made. The sounds are generated by mechanical resonators and capacitive displacement sensors. Damping by air scales unfavourably for generating audible frequencies with small devices.

  15. Instrumental activation analysis of molybdenites

    International Nuclear Information System (INIS)

    Geisler, M.; Schelhorn, H.

    1981-01-01

    Na, K, Sc, Cr, Fe, Co, Se, Rb, Ag, Cs, Ba, La, Ce, Eu, Yb, Hf, W, Re, and Th have been determined in 6 molybdenite samples by instrumental activation analysis. The samples were of different origin and showed K, Sc, W, and Re values with differences of more than two orders of magnitude, whereas Sc values were within one order of magnitude

  16. Scientific Instruments and Epistemology Engines

    Czech Academy of Sciences Publication Activity Database

    Dvořák, Tomáš

    2012-01-01

    Roč. 34, č. 4 (2012), s. 529-540 ISSN 1210-0250 R&D Projects: GA ČR(CZ) GAP401/11/2338 Institutional support: RVO:67985955 Keywords : material culture of science * scientific instruments * epistemology engines * experimental systems Subject RIV: AA - Philosophy ; Religion

  17. Instrumentation for PIXE and RBS

    International Nuclear Information System (INIS)

    2000-12-01

    The purpose of this document is to give an overview of instrumentation for PIXE and Rutherford backscattering analysis, including hardware and software needed to perform the analysis, including detectors, analyzers, data acquisition systems and data analysis software. It also provides some information on accelerators needed for these applications

  18. Technological considerations in emergency instrument preparedness

    International Nuclear Information System (INIS)

    Selby, J.M.

    1975-01-01

    The types of emergency instrumentation systems necessary to characterize the severity and extent of radiation accidents and to aid in the protection of operating personnel and personnel living near the plant are discussed. These include instruments for direct measurement of the airborne radioactive material within the facility, fixed instrumentation for ambient dose rate monitoring or area monitoring, and portable instruments for environmental monitoring

  19. Temperature documentation - instrument for quality assurance; Temperaturdokumentation - Instrument der Qualitaetssicherung

    Energy Technology Data Exchange (ETDEWEB)

    Hegglin, A [Wurm AG, Winterthur (Switzerland)

    2000-10-01

    Important inspection points of a HACCP concept are the temperatures. On the basis of the demands for a systematic temperature documentation, the application of control systems and instruments is described by several examples. (orig.) [German] Wichtige Kontrollpunkte eines HACCP-Konzepts sind die Temperaturen. Ausgehend von den Anforderungen, die an eine systematische Temperaturedokumentation gestellt werden, wird der Einsatz geeigneter Regel- und Ueberwachungsgeraete an mehreren Beispielen erlaeutert. (orig.)

  20. Instrumentation requirements for the ESF thermomechanical experiments

    International Nuclear Information System (INIS)

    Pott, J.; Brechtel, C.E.

    1992-01-01

    In situ thermomechanical experiments are planned as part of the Yucca Mountain Site Characterization Project that require instruments to measure stress and displacement at temperatures that exceed the typical specifications of existing geotechnical instruments. A high degree of instrument reliability will also be required to satisfy the objectives of the experiments, therefore a study was undertaken to identify areas where improvement in instrument performance was required. A preliminary list of instruments required for the experiments was developed, based on existing test planning and analysis. Projected temperature requirements were compared to specifications of existing instruments to identify instrumentation development needs. Different instrument technologies, not currently employed in geotechnical instrumentation, were reviewed to identify potential improvements of existing designs for the high temperature environment. Technologies with strong potentials to improve instrument performance with relatively high reliability include graphite fiber composite materials, fiber optics, and video imagery

  1. Analysis of instrumentation technology for SMART

    International Nuclear Information System (INIS)

    Hur, Seop; Koo, I. S.; Park, H. Y.; Lee, C. K.; Kim, D. H.; Suh, Y. S.; Seong, S. H.; Jang, G. S.

    1998-03-01

    It is necessary that development requirements, techniques to be developed, and development tasks and approach are established to develop the SMART instrumentation system. It is important to establish the development strategies for input for developing SMART instrumentation system. To meet above needs, the industry general and nuclear instrumentation techniques were analyzed and reviewed, respectively, based on the classification of instrumentation to analyze the industrial instrumentation techniques, and analysis results which described the inherent merits and demerits of each technique can be used for inputs to select the instruments for SMART. For the instrumentation techniques for nuclear environments, the major instrumentation techniques were reviewed, and the instrumentation system were established. The following development approaches were established based on the development requirements and the analysis results of research and development trends of industrial and nuclear instrumentation techniques. (author). 90 refs., 38 tabs., 33 figs

  2. The history of thoracic surgical instruments and instrumentation.

    Science.gov (United States)

    Hagopian, E J; Mann, C; Galibert, L A; Steichen, F M

    2000-02-01

    Thoracic surgical practice has evolved from the innovations of its pioneers. Beginning with the stethoscope discovered by Laënnec with his system of auscultation, to the tools we use in the dissection and control of the hilum of the lung for resection, our practice of thoracic surgery has been entwined with the development of instruments and instrumentation. The development of strategies to prevent death from the open pneumothorax began with manual control of the mediastinum and progressed through differential pressure to, finally, the technique of intubation and the methods of positive-pressure and insufflation anesthesia. The instruments we place in our hands are not enough to define our art. Entry into the chest would not be possible without the use of rib retractors, rib shears, and even periosteal elevators. Finally, to the present day of minimally invasive techniques and the application of thoracoscopy for therapeutic purposes, we find the efforts of our predecessors well developed. For the progression from the fear of the open pneumothorax to the present-day state of the ease of thoracotomy for lung resection we are indebted to those who gave so much of their time and, for some, their lives to death from tuberculosis, to allow the advancement of our practice of surgery. These great people should be remembered not only for their acceptance of novel ideas but also, more importantly, for their lack of fear of testing them.

  3. Development of CAMAC and Fastbus instrumentation

    International Nuclear Information System (INIS)

    Venkateswaran, Aruna; Behere, Anita; Ghodgaonkar, M.D.; Bairi, B.R.

    1987-01-01

    This report describes the work being done towards the development of CAMAC and Fast Bus Instrumentation under the VII Five Year Plan Project 'Modernisation of Reactor Control Instrumentation and Development of CAMAC and FAST BUS Instrumentation'. The report summarises the goals, objectives, principles and concepts of CAMAC and Fast Bus Instrumentation. While emphasizing the motivation behind the development of CAMAC and Fast Bus Instrumentation, the report brings out the current status and future plans of this development program. (author)

  4. ACRF Instrumentation Status and Information September 2009

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2009-10-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  5. ACRF Instrumentation Status and Information April 2009

    Energy Technology Data Exchange (ETDEWEB)

    Voyles, JW

    2009-05-07

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  6. ACRF Instrumentation Status and Information August 2009

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2009-09-09

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  7. ACRF Instrumentation Status and Information July 2009

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2009-08-13

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  8. ACRF Instrumentation Status and Information - June 2009

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2009-06-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  9. ACRF Instrumentation Status and Information May 2009

    Energy Technology Data Exchange (ETDEWEB)

    JW Voyles

    2009-05-01

    The purpose of this report is to provide a concise but comprehensive overview of Atmospheric Radiation Measurement Climate Research Facility instrumentation status. The report is divided into the following five sections: (1) new instrumentation in the process of being acquired and deployed, (2) field campaigns, (3) existing instrumentation and progress on improvements or upgrades, (4) proposed future instrumentation, and (5) Small Business Innovation Research instrument development.

  10. Robust Instrumentation[Water treatment for power plant]; Robust Instrumentering

    Energy Technology Data Exchange (ETDEWEB)

    Wik, Anders [Vattenfall Utveckling AB, Stockholm (Sweden)

    2003-08-01

    Cementa Slite Power Station is a heat recovery steam generator (HRSG) with moderate steam data; 3.0 MPa and 420 deg C. The heat is recovered from Cementa, a cement industry, without any usage of auxiliary fuel. The Power station commenced operation in 2001. The layout of the plant is unusual, there are no similar in Sweden and very few world-wide, so the operational experiences are limited. In connection with the commissioning of the power plant a R and D project was identified with the objective to minimise the manpower needed for chemistry management of the plant. The lean chemistry management is based on robust instrumentation and chemical-free water treatment plant. The concept with robust instrumentation consists of the following components; choice of on-line instrumentation with a minimum of O and M and a chemical-free water treatment. The parameters are specific conductivity, cation conductivity, oxygen and pH. In addition to that, two fairly new on-line instruments were included; corrosion monitors and differential pH calculated from specific and cation conductivity. The chemical-free water treatment plant consists of softening, reverse osmosis and electro-deionisation. The operational experience shows that the cycle chemistry is not within the guidelines due to major problems with the operation of the power plant. These problems have made it impossible to reach steady state and thereby not viable to fully verify and validate the concept with robust instrumentation. From readings on the panel of the online analysers some conclusions may be drawn, e.g. the differential pH measurements have fulfilled the expectations. The other on-line analysers have been working satisfactorily apart from contamination with turbine oil, which has been noticed at least twice. The corrosion monitors seem to be working but the lack of trend curves from the mainframe computer system makes it hard to draw any clear conclusions. The chemical-free water treatment has met all

  11. CERCA's fuel elements instrumentation manufacturing

    International Nuclear Information System (INIS)

    Harbonnier, G.; Jarousse, C.; Pin, T.; Febvre, M.; Colomb, P.

    2005-01-01

    When research and test reactors wish to further understand the Fuel Elements behavior when operating as well as mastering their irradiation conditions, operators carry out neutron and thermo hydraulic analysis. For thermal calculation, the codes used have to be preliminary validated, at least in the range of the reactor safety operational limits. When some further investigations are requested either by safety authorities or for its own reactor needs, instrumented tools are the ultimate solution for providing representative measurements. Such measurements can be conducted for validating thermal calculation codes, at nominal operating condition as well as during transients ones, or for providing numerous and useful data in the frame of a new products qualification program. CERCA, with many years of experience for implanting thermocouples in various products design, states in this poster his manufacturing background on instrumented elements, plates or targets. (author)

  12. Nuclear instrumentation for radiation measurement

    International Nuclear Information System (INIS)

    Madan, V.K.

    2012-01-01

    Nuclear radiation cannot be detected by human senses. Nuclear detectors and associated electronics facilitate detection and measurement of different types of radiation like alpha particles, beta particles, gamma radiation, and detection of neutrons. Nuclear instrumentation has evolved greatly since the discovery of radioactivity. There has been tremendous advancement in detector technology, electronics, computer technology, and development of efficient algorithms and methods for spectral processing to extract precisely qualitative and quantitative information of the radiation. Various types of detectors and nuclear instruments are presently available and are used for different applications. This paper describes nuclear radiation, its detection and measurement and associated electronics, spectral information extraction, and advances in these fields. The paper also describes challenges in this field

  13. Modernization of ILL instrument electronics

    International Nuclear Information System (INIS)

    Descamps, F.

    1999-01-01

    We have built new general purpose cards for data acquisition taking advantage of recent developments in electronics. At the end of the year, most scheduled instruments at the ILL will be running under UNIX with VME electronics front-end. As the VME electronics of the ILL was designed at the beginning of the eighties, the instrument control section (SCI) at ILL has prepared a renewal plan for two reasons: - first, all the processor cards of the Institute are based on MIZAR processor boards and MIZAR stopped the production of this card last year, as the market was shrinking; - in addition, processors and programmable electronics are now 10 times faster. The electronics services want to take full advantage of these new performances. (author)

  14. Evaluation Framework for Search Instruments

    International Nuclear Information System (INIS)

    Warren, Glen A.; Smith, Leon E.; Cooper, Matt W.; Kaye, William R.

    2005-01-01

    A framework for quantitatively evaluating current and proposed gamma-ray search instrument designs has been developed. The framework is designed to generate a large library of ''virtual neighborhoods'' that can be used to test and evaluate nearly any gamma-ray sensor type. Calculating nuisance-source emissions and combining various sources to create a large number of random virtual scenes places a significant computational burden on the development of the framework. To reduce this burden, a number of radiation transport simplifications have been made which maintain the essential physics ingredients for the quantitative assessment of search instruments while significantly reducing computational times. The various components of the framework, from the simulation and benchmarking of nuisance source emissions to the computational engine for generating the gigabytes of simulated search scenes, are discussed

  15. Instrumental Landing Using Audio Indication

    Science.gov (United States)

    Burlak, E. A.; Nabatchikov, A. M.; Korsun, O. N.

    2018-02-01

    The paper proposes an audio indication method for presenting to a pilot the information regarding the relative positions of an aircraft in the tasks of precision piloting. The implementation of the method is presented, the use of such parameters of audio signal as loudness, frequency and modulation are discussed. To confirm the operability of the audio indication channel the experiments using modern aircraft simulation facility were carried out. The simulated performed the instrument landing using the proposed audio method to indicate the aircraft deviations in relation to the slide path. The results proved compatible with the simulated instrumental landings using the traditional glidescope pointers. It inspires to develop the method in order to solve other precision piloting tasks.

  16. Nuclear instrumentation for uranium exploration

    International Nuclear Information System (INIS)

    Sarma, Ch. V.N.; Sarma, C.V.R.; Sreehari, R.

    1999-01-01

    Instrumentation required for uranium exploration may be broadly classified based on surface and sub-surface measurement of gamma-ray intensity. Surface measurement of gross and spectral gamma intensity are carried out by employing portable Geiger Mueller/scintillation counters and four-channel spectrometers. Measurement of thoron ( 220 Rn) and radon ( 222 Rn) in the soil gas is being carried out by closed circuit technique using radon measuring system. Radiometric mapping of trenches, pits and mine-faces are carried out using shielded probe with 2π source geometry, whereas logging sonde with instruments through the steel armoured cable are employed for point to 4π geometry. Spectral borehole logging system with built-in multi-channel analyser (MCA) has been developed for the uranium exploration programme for AMD. Note-book PC based high sensitivity air-borne gamma-ray spectrometric survey system has been designed, developed and test flown. (author)

  17. Epithermal neutron instrumentation at ISIS

    International Nuclear Information System (INIS)

    Gorini, G; Festa, G; Andreani, C

    2014-01-01

    The advent of pulsed neutron sources makes available high epithermal neutron fluxes (in the energy range between 500 meV and 100 eV). New dedicated instrumentation, such as Resonance Detectors, was developed at ISIS spallation neutron source in the last years to apply the specific properties of this kind of neutron beam to the study of condensed matter. New detection strategies like Filter Difference method and Foil Cycling Technique were also developed in parallel to the detector improvement at the VESUVIO beamline. Recently, epithermal neutron beams were also used at the INES beamline to study elemental and isotopic composition of materials, with special application to cultural heritage studies. In this paper we review a series of epithermal neutron instrumentation developed at ISIS, their evolution over time and main results obtained

  18. Holy Trinity of Instrumentation Development

    International Nuclear Information System (INIS)

    Ursic, Rok; Solar, Borut

    2004-01-01

    Being user friendly should be the main guidance, beside the self-understood high performance, in today's instrumentation development. Here we identify three components of the user-friendly policy: the all-in-one concept, customization, and connectivity. All-in-one is the concept of unification of various building blocks and thus various functionalities in one product. The customization is enabled by the product's reconfigurability that allows a product to grow and support new requirements and applications without changing hardware. The consequence of the two is the capacity of the single instrument to perform a variety of tasks that before were split among different devices. The last of the three is connectivity that improves the relationship between controls and beam diagnostics, brings out-of-the-crate freedom, and opens unforeseen possibilities for intra-accelerator cooperation and remote technical support

  19. Digital readout alpha survey instrument

    International Nuclear Information System (INIS)

    Jacobs, M.E.

    1976-01-01

    A prototype solid-state digital readout alpha particle survey instrument has been designed and constructed. The meter incorporates a Ludlum alpha scintillator as a detector, digital logic circuits for control and timing, and a Digilin counting module with reflective liquid crystal display. The device is used to monitor alpha radiation from a surface. Sample counts are totalized over 10-second intervals and displayed digitally in counts per minute up to 19,999. Tests over source samples with counts to 15,600 cpm have shown the device to be rapid, versatile and accurate. The instrument can be fabricated in one man-week and requires about $835 in material costs. A complete set of drawings is included

  20. High resolution tomographic instrument development

    International Nuclear Information System (INIS)

    1992-01-01

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefited greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational

  1. Mass Spectrometry Instrumentation in Proteomics

    DEFF Research Database (Denmark)

    Sprenger, Richard Remko; Roepstorff, Peter

    2012-01-01

    Mass spectrometry has evolved into a crucial technology for the field of proteomics, enabling the comprehensive study of proteins in biological systems. Innovative developments have yielded flexible and versatile mass spectrometric tools, including quadrupole time-of-flight, linear ion trap......, Orbitrap and ion mobility instruments. Together they offer various and complementary capabilities in terms of ionization, sensitivity, speed, resolution, mass accuracy, dynamic range and methods of fragmentation. Mass spectrometers can acquire qualitative and quantitative information on a large scale...

  2. Beam diagnostic instruments of TARN

    International Nuclear Information System (INIS)

    Watanabe, Shin-ichi.

    1987-09-01

    The paper summarizes the beam diagnostic instruments of the low energy ion accumulation ring; TARN. With these monitors, position, profiles, bunch structure, intensity, emittance and momentum spread were measured to evaluate the injection and stacking experiments. The monitors provide the sensitivity of a few μA for the nondestructive and a few nA for the destructive monitors. Discussions on monitor probe and electronics are presented on the basis of an achievement of the beam stacking experiments. (author)

  3. Peer Learning in Instrumental Practicing

    Science.gov (United States)

    Nielsen, Siw G.; Johansen, Guro G.; Jørgensen, Harald

    2018-01-01

    In higher music education (HME), the notion of “private teaching, private learning” has a long tradition, where the learning part rests on the student's individual practicing between instrumental lessons. However, recent research suggests that collaborative learning among peers is beneficial in several aspects, such as sense of belonging, motivation and self-efficacy. This is consistent with the concept of vicarious learning. In this study, we conducted a survey among bachelor music students in church music, performance or music education programs enrolled in a music academy (N = 96), where parts of the questionnaire addressed peer learning and peer's influence on the students's instrumental practicing, and the degree of satisfaction with their practicing. These issues were seen in relation to gender, musical genre and study program. Overall, the students reported engaging in peer learning related to their instrumental practicing, to various degrees. This involved discussing practicing matters with peers, and practicing together with peers. However, student's reports of their views on peer learning, show that they perceive it more beneficial than the amount of time reported doing it would indicate. No significant gender differences were found, but students within improvised music/jazz engaged the most in peer learning, and church music students the least. Neither the degree of engaging in peer learning nor reported influence from peers correlated significantly with the degree of satisfaction. We discuss whether a general dissatisfaction is caused by being in a competitive learning environment combined with a privatized culture for learning. Finally, we suggest that collaborative forums for instrumental practicing within HME institutions can function as constructive and supportive arenas to enhance students learning and inner motivation. PMID:29599738

  4. Nuclear instrumentation cable end seal

    International Nuclear Information System (INIS)

    Cannon, C.P.; Brown, D.P.

    1979-01-01

    An improved coaxial end seal for hermetically sealed nuclear instrumentation cable exhibiting an improved breakdown pulse noise characteristic under high voltage, high temperature conditions is described. A tubular insulator body has metallized interior and exterior surface portions which are braze sealed to a center conductor and an outer conductive sheath. The end surface of the insulator body which is directed toward the coaxial cable to which it is sealed has a recessed surface portion within which the braze seal material terminates

  5. Peer Learning in Instrumental Practicing.

    Science.gov (United States)

    Nielsen, Siw G; Johansen, Guro G; Jørgensen, Harald

    2018-01-01

    In higher music education (HME), the notion of "private teaching, private learning" has a long tradition, where the learning part rests on the student's individual practicing between instrumental lessons. However, recent research suggests that collaborative learning among peers is beneficial in several aspects, such as sense of belonging, motivation and self-efficacy. This is consistent with the concept of vicarious learning. In this study, we conducted a survey among bachelor music students in church music, performance or music education programs enrolled in a music academy ( N = 96), where parts of the questionnaire addressed peer learning and peer's influence on the students's instrumental practicing, and the degree of satisfaction with their practicing. These issues were seen in relation to gender, musical genre and study program. Overall, the students reported engaging in peer learning related to their instrumental practicing, to various degrees. This involved discussing practicing matters with peers, and practicing together with peers. However, student's reports of their views on peer learning, show that they perceive it more beneficial than the amount of time reported doing it would indicate. No significant gender differences were found, but students within improvised music/jazz engaged the most in peer learning, and church music students the least. Neither the degree of engaging in peer learning nor reported influence from peers correlated significantly with the degree of satisfaction. We discuss whether a general dissatisfaction is caused by being in a competitive learning environment combined with a privatized culture for learning. Finally, we suggest that collaborative forums for instrumental practicing within HME institutions can function as constructive and supportive arenas to enhance students learning and inner motivation.

  6. Virtual Instrumentation in Biomedical Equipment

    Directory of Open Access Journals (Sweden)

    Tiago Faustino Andrade

    2013-01-01

    Full Text Available Nowadays, the assessment of body composition by estimating the percentage of body fat has a great impact in many fields such as nutrition, health, sports, chronic diseases and others. The main purpose for this work is the development of a virtual instrument that permits more effective assessment of body fat, automatic data processing, recording results and storage in a database, with high potential to conduct new studies, http://lipotool.com.

  7. SMAP Instrument Mechanical System Engineering

    Science.gov (United States)

    Slimko, Eric; French, Richard; Riggs, Benjamin

    2013-01-01

    The Soil Moisture Active Passive (SMAP) mission, scheduled for launch by the end of 2014, is being developed to measure the soil moisture and soil freeze/thaw state on a global scale over a three-year period. The accuracy, resolution, and global coverage of SMAP measurements are invaluable across many science and applications disciplines including hydrology, climate, carbon cycle, and the meteorological, environment, and ecology applications communities. The SMAP observatory is composed of a despun bus and a spinning instrument platform that includes both a deployable 6 meter aperture low structural frequency Astromesh reflector and a spin control system. The instrument section has engendered challenging mechanical system issues associated with the antenna deployment, flexible antenna pointing in the context of a multitude of disturbances, spun section mass properties, spin control system development, and overall integration with the flight system on both mechanical and control system levels. Moreover, the multitude of organizations involved, including two major vendors providing the spin subsystem and reflector boom assembly plus the flight system mechanical and guidance, navigation, and control teams, has led to several unique system engineering challenges. Capturing the key physics associated with the function of the flight system has been challenging due to the many different domains that are applicable. Key interfaces and operational concepts have led to complex negotiations because of the large number of organizations that integrate with the instrument mechanical system. Additionally, the verification and validation concerns associated with the mechanical system have had required far-reaching involvement from both the flight system and other subsystems. The SMAP instrument mechanical systems engineering issues and their solutions are described in this paper.

  8. Soil analysis. Modern instrumental technique

    International Nuclear Information System (INIS)

    Smith, K.A.

    1993-01-01

    This book covers traditional methods of analysis and specialist monographs on individual instrumental techniques, which are usually not written with soil or plant analysis specifically in mind. The principles of the techniques are combined with discussions of sample preparation and matrix problems, and critical reviews of applications in soil science and related disciplines. Individual chapters are processed separately for inclusion in the appropriate data bases

  9. Peer Learning in Instrumental Practicing

    Directory of Open Access Journals (Sweden)

    Siw G. Nielsen

    2018-03-01

    Full Text Available In higher music education (HME, the notion of “private teaching, private learning” has a long tradition, where the learning part rests on the student's individual practicing between instrumental lessons. However, recent research suggests that collaborative learning among peers is beneficial in several aspects, such as sense of belonging, motivation and self-efficacy. This is consistent with the concept of vicarious learning. In this study, we conducted a survey among bachelor music students in church music, performance or music education programs enrolled in a music academy (N = 96, where parts of the questionnaire addressed peer learning and peer's influence on the students's instrumental practicing, and the degree of satisfaction with their practicing. These issues were seen in relation to gender, musical genre and study program. Overall, the students reported engaging in peer learning related to their instrumental practicing, to various degrees. This involved discussing practicing matters with peers, and practicing together with peers. However, student's reports of their views on peer learning, show that they perceive it more beneficial than the amount of time reported doing it would indicate. No significant gender differences were found, but students within improvised music/jazz engaged the most in peer learning, and church music students the least. Neither the degree of engaging in peer learning nor reported influence from peers correlated significantly with the degree of satisfaction. We discuss whether a general dissatisfaction is caused by being in a competitive learning environment combined with a privatized culture for learning. Finally, we suggest that collaborative forums for instrumental practicing within HME institutions can function as constructive and supportive arenas to enhance students learning and inner motivation.

  10. High resolution tomographic instrument development

    Energy Technology Data Exchange (ETDEWEB)

    1992-08-01

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefited greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  11. High resolution tomographic instrument development

    Energy Technology Data Exchange (ETDEWEB)

    1992-01-01

    Our recent work has concentrated on the development of high-resolution PET instrumentation reflecting in part the growing importance of PET in nuclear medicine imaging. We have developed a number of positron imaging instruments and have the distinction that every instrument has been placed in operation and has had an extensive history of application for basic research and clinical study. The present program is a logical continuation of these earlier successes. PCR-I, a single ring positron tomograph was the first demonstration of analog coding using BGO. It employed 4 mm detectors and is currently being used for a wide range of biological studies. These are of immense importance in guiding the direction for future instruments. In particular, PCR-II, a volume sensitive positron tomograph with 3 mm spatial resolution has benefited greatly from the studies using PCR-I. PCR-II is currently in the final stages of assembly and testing and will shortly be placed in operation for imaging phantoms, animals and ultimately humans. Perhaps the most important finding resulting from our previous study is that resolution and sensitivity must be carefully balanced to achieve a practical high resolution system. PCR-II has been designed to have the detection characteristics required to achieve 3 mm resolution in human brain under practical imaging situations. The development of algorithms by the group headed by Dr. Chesler is based on a long history of prior study including his joint work with Drs. Pelc and Reiderer and Stearns. This body of expertise will be applied to the processing of data from PCR-II when it becomes operational.

  12. TECHNICAL TRAINING SEMINAR: National Instruments

    CERN Multimedia

    Monique Duval

    2004-01-01

    From 9:30 to 12:00 and from 13:00 to 16:00 hrs - Council Chamber, Salle B, Salle des Pas Perdus National Instruments (NI) on Tour 2004 Claudia Jüngel, Evrem Yarkin, Joel Clerc, Hervé Baour / NATIONAL INSTRUMENTS The special event NI on Tour 2004, run in Germany, Austria and Switzerland, will be at CERN on March 30. Technical seminars and free introductory courses will be offered all day long in the Council Chamber, Salle B, and Salle des Pas Perdus (buildings 61 and 503). Data acquisition systems on PCs, industrial measurement and control techniques, advanced LabVIEW software and PXI instrumentation, and system components for tests and automation will be presented. Walk-in courses will address DIAdem, LabVIEW and data acquisition. Language: English and French Free seminars and courses, no registration Organisers: Rolf Stampfli / IT-CO / 78102 & 160367 / Rolf.Stampfli@cern.ch Davide Vitè / HR-PMD-ATT / 75141 Davide.Vite@cern.ch For more information and the complete event programme, please visit the...

  13. Geotechnical instrumentation for repository shafts

    International Nuclear Information System (INIS)

    Lentell, R.L.; Byrne, J.

    1993-01-01

    The US Congress passed the Nuclear Waste Policy Act in 1980, which required that three distinctly different geologic media be investigated as potential candidate sites for the permanent disposal of high-level nuclear waste. The three media that were selected for study were basalt (WA), salt (TX, LA, MS, UT), and tuff (NV). Preliminary Exploratory Shaft Facilities (ESF) designs were prepared for seven candidate salt sites, including bedded and domal salt environments. A bedded-salt site was selected in Deaf Smith County, TX for detailed site characterization studies and ESF Final Design. Although Congress terminated the Salt Repository Program in 1988, Final Design for the Deaf Smith ESF was completed, and much of the design rationale can be applied to subsequent deep repository shafts. This paper presents the rationale for the geotechnical instrumentation that was designed for construction and operational performance monitoring of the deep shafts of the in-situ test facility. The instrumentation design described herein can be used as a general framework in designing subsequent instrumentation programs for future high-level nuclear waste repository shafts

  14. The instrumentation of fast reactor

    International Nuclear Information System (INIS)

    Endo, Akira

    2003-03-01

    The author has been engaged in the development of fast reactors over the last 30 years with both an involvement with the early technology development on the experimental breeder reactor Joyo, and latterly continuing this work on the prototype breeder reactor, Monju. In order to pass on this experience to younger engineers this paper is produced to outline this experience in the sincere hope that the information given will be utilised in future educational training material. The paper discusses the wide diversity on the associated instrument technology which the fast breeder reactor requires. The first chapter outlines the fast reactor system, followed by discussions on reactor instrumentation, measurement principles, temperature dependencies, and verification response characteristics from various viewpoints, are discussed in chapters two and three. The important issues of failed fuel location detection, and sodium leak detection from steam generators are discussed in chapters 4 and 5 respectively. Appended to this report is an explanation on the methods of measuring response characteristics on instrumentation systems using error analysis, random signal theory and measuring method of response characteristic by AR (autoregressive) model on which it appears is becoming an indispensable problem for persons involved with this technology in the future. (author)

  15. Measuring instruments of corporate reputation

    Directory of Open Access Journals (Sweden)

    Damir Grgić

    2008-12-01

    Full Text Available The subject of this paper is focused on the instruments for the measurement of corporate reputation. Recent research of the elements which influence the success of a company shows a growing interest in intangible values. Corporate reputation itself has been identified as one of the key intangible assets which create the company’s added value. Understanding of the importance of corporate reputation has been determined as a significant component of the company’s competitiveness, that is, of its competitive edge. Reputation is a normal part of our life and an integral part of our society. Our interest in the honesty and integrity of others is firmly established in all cultures and nowadays the focus of this interest is switching increasingly on companies. Corporate reputation can be acquired by means of strong, well-developed strategies, which are crucial for the opinion of stakeholders regarding future stability and competitive sustainability of the company. On the other hand, it should be emphasized that in order to manage it, corporate reputation has to be measured first. However, although the concept of corporate reputation is universally accepted and its significance has been recognized especially in the last two decades, the process of its measurement is still at an early stage and there is no universally accepted instrument for its measurement. Therefore, the author of this paper gives an overview of the instruments used for the measurement of corporate reputation which have gained a foothold through former practical usage.

  16. Tool – Material, Metaphor – Metonymy, Instrument(ness)

    DEFF Research Database (Denmark)

    Bertelsen, Olav Wedege; Breinbjerg, Morten; Pold, Søren

    2008-01-01

    creativity , supported by analysis of, and interviews with, musical composers. Instrumentness is explained through discussions of materiality and metonymy as central strategies for computer mediated creativity. The paper is contributing to an investigation of the aesthetics of use in relation to software...... are controlled and conceptualized through values such as virtuosity and palyability, which are important for computer-mediated creative work supporting development in use beyond what is initially designed for. The papet performs a conceptual investigation into qualities in software interfaces that support...

  17. Multimodality instrument for tissue characterization

    Science.gov (United States)

    Mah, Robert W. (Inventor); Andrews, Russell J. (Inventor)

    2004-01-01

    A system with multimodality instrument for tissue identification includes a computer-controlled motor driven heuristic probe with a multisensory tip. For neurosurgical applications, the instrument is mounted on a stereotactic frame for the probe to penetrate the brain in a precisely controlled fashion. The resistance of the brain tissue being penetrated is continually monitored by a miniaturized strain gauge attached to the probe tip. Other modality sensors may be mounted near the probe tip to provide real-time tissue characterizations and the ability to detect the proximity of blood vessels, thus eliminating errors normally associated with registration of pre-operative scans, tissue swelling, elastic tissue deformation, human judgement, etc., and rendering surgical procedures safer, more accurate, and efficient. A neural network program adaptively learns the information on resistance and other characteristic features of normal brain tissue during the surgery and provides near real-time modeling. A fuzzy logic interface to the neural network program incorporates expert medical knowledge in the learning process. Identification of abnormal brain tissue is determined by the detection of change and comparison with previously learned models of abnormal brain tissues. The operation of the instrument is controlled through a user friendly graphical interface. Patient data is presented in a 3D stereographics display. Acoustic feedback of selected information may optionally be provided. Upon detection of the close proximity to blood vessels or abnormal brain tissue, the computer-controlled motor immediately stops probe penetration. The use of this system will make surgical procedures safer, more accurate, and more efficient. Other applications of this system include the detection, prognosis and treatment of breast cancer, prostate cancer, spinal diseases, and use in general exploratory surgery.

  18. Electrolytic preconcentration in instrumental analysis.

    Science.gov (United States)

    Sioda, R E; Batley, G E; Lund, W; Wang, J; Leach, S C

    1986-05-01

    The use of electrolytic deposition as a separation and preconcentration step in trace metal analysis is reviewed. Both the principles and applications of the technique are dealt with in some detail. Electrolytic preconcentration can be combined with a variety of instrumental techniques. Special attention is given to stripping voltammetry, potentiometric stripping analysis, different combinations with atomic-absorption spectrometry, and the use of flow-through porous electrodes. It is pointed out that the electrolytic preconcentration technique deserves more extensive use as well as fundamental investigation.

  19. In-pile Instrumentation Development

    International Nuclear Information System (INIS)

    Vermeeren, L.

    2005-01-01

    Advanced irradiations in research reactors require the on-line monitoring of crucial parameters like neutron fluxes, gamma dose rates, central fuel rod temperatures, fission gas release pressures and small geometry changes. Our activities in this field aim at a detailed understanding of the sensor behaviour in the irradiation conditions in order to extract reliable real-time information. The objectives of work performed by SCK-CEN are to study of the on-line in-pile measurement of gamma and neutron fluxes in real time and to investigate parasitic radiation-induced signals in instrumentation cables

  20. Tevatron instrumentation: boosting collider performance

    Energy Technology Data Exchange (ETDEWEB)

    Shiltsev, Vladimir; Jansson, Andreas; Moore, Ronald; /Fermilab

    2006-05-01

    The Tevatron in Collider Run II (2001-present) is operating with six times more bunches, many times higher beam intensities and luminosities than in Run I (1992-1995). Beam diagnostics were crucial for the machine start-up and the never-ending luminosity upgrade campaign. We present the overall picture of the Tevatron diagnostics development for Run II, outline machine needs for new instrumentation, present several notable examples that led to Tevatron performance improvements, and discuss the lessons for the next big machines--LHC and ILC.

  1. Instrumentation in high energy physics

    International Nuclear Information System (INIS)

    Serin, L.

    2007-01-01

    The instrumentation in high energy physics is a wide and advanced domain which cannot be covered in a single lesson. The main basic physics processes for charged and neutral particles are recalled with the definition of a few concepts needed to understand or design a detector. The application of these principles to charged particle measurement devices (momentum), light detection or energy measurement are presented mostly with examples from collider experiments. The particle identification which is often the combination of different techniques in a same experiment is also discussed. Finally in a very short section, a few considerations about electronics/processing with their impact on the detector performance are given

  2. Rapidly Adaptable Instrumentation Tester (RAIT)

    International Nuclear Information System (INIS)

    Vargo, Timothy D.

    1999-01-01

    Emerging technologies in the field of ''Test ampersand Measurement'' have recently enabled the development of the Rapidly Adaptable Instrumentation Tester (RAIT). Based on software developed with LabVIEW, the RAIT design enables quick reconfiguration to test and calibrate a wide variety of telemetry systems. The consequences of inadequate testing could be devastating if a telemetry system were to fail during an expensive flight mission. Supporting both open-bench testing as well as automated test sequences, the RAIT has significantly lowered total time required to test and calibrate a system. This has resulted in an overall lower per unit testing cost than has been achievable in the past

  3. Financial instrument pricing using C++

    CERN Document Server

    Duffy, Daniel J

    2004-01-01

    One of the best languages for the development of financial engineering and instrument pricing applications is C++. This book has several features that allow developers to write robust, flexible and extensible software systems. The book is an ANSI/ISO standard, fully object-oriented and interfaces with many third-party applications. It has support for templates and generic programming, massive reusability using templates (?write once?) and support for legacy C applications. In this book, author Daniel J. Duffy brings C++ to the next level by applying it to the design and implementation of class

  4. Performing instrumentation and controls upgrades

    International Nuclear Information System (INIS)

    Kessler, F. M.; Connell, T. J.; Ryan, M. P.

    1992-01-01

    I and C upgrades are comprised of a varying range of content, complexity, expansiveness, and criticality. There are common threads in all upgrades which can be simplified by the development of a long term I and C upgrade plan. The development of a such a plan can establish effective ground rules for upgrades, large and small. It can be the basis from which to begin an upgrade evaluation and the standard which is used to compare the degree of compliance of any upgrade regarding the plan or to define the differences from the plan and an individual upgrade. Primary motivation for I and C upgrades are obsolescence and unavailability of spare parts. Numerous other areas of consideration are also involved in an upgrade. Today's technology results in most upgrades largely or totally utilizing digital equipment. The use of digital equipment is fairly new in many I and C applications and requires an elaborate evaluation from functional, qualification, operational, and licensing perspectives as well as others. A well defined upgrade plan developed as a basis for I and C upgrades is a significant start to ensuring an effective upgrade process. Properly developed and implemented, the plan will support I and C upgrade efforts to ensure that the intricacies associated with such tasks eliminate the existing problems which require the upgrade to be performed. The upgrade plan also results in ensuring the maximum benefit from all perspectives of the plant enhancements being carried out and considered for future implementation. Instrumentation and controls aging and replacement are issues of growing importance due to the potential for significant impact on plant operation and efficiency. Obsolescence and unavailability of spare parts are major drivers towards evaluating the cost benefits of upgrading current equipment. In addition to these two primary factors, the advantages of utilizing digital equipment have also become of prime importance when evaluating instrumentation and

  5. The 2007 ESO Instrument Calibration Workshop

    CERN Document Server

    Kaufer, Andreas; ESO Workshop

    2008-01-01

    The 2007 ESO Instrument Calibration workshop brought together more than 120 participants with the objective to a) foster the sharing of information, experience and techniques between observers, instrument developers and instrument operation teams, b) review the actual precision and limitations of the applied instrument calibration plans, and c) collect the current and future requirements by the ESO users. These present proceedings include the majority of the workshop’s contributions and document the status quo of instrument calibration at ESO in large detail. Topics covered are: Optical Spectro-Imagers, Optical Multi-Object Spectrographs, NIR and MIR Spectro-Imagers, High-Resolution Spectrographs, Integral Field Spectrographs, Adaptive Optics Instruments, Polarimetric Instruments, Wide Field Imagers, Interferometric Instruments as well as other crucial aspects such as data flow, quality control, data reduction software and atmospheric effects. It was stated in the workshop that "calibration is a life-long l...

  6. GRIP LIGHTNING INSTRUMENT PACKAGE (LIP) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The GRIP Lightning Instrument Package (LIP) dataset was collected by the Lightning Instrument Package (LIP), which consists of 6 rotating vane type electric field...

  7. GRIP LIGHTNING INSTRUMENT PACKAGE (LIP) V1

    Data.gov (United States)

    National Aeronautics and Space Administration — The Lightning Instrument Package (LIP) consists of 6 rotating vane type electric field sensors along with a central computer to record and monitor the instruments....

  8. Instrumentation for three-dimensional tomography

    International Nuclear Information System (INIS)

    Derenzo, S.E.

    1981-01-01

    The Donner 280-crystal positron tomograph is described and its operation is explained. The instrument was put into operation in 1978. Possible uses of this instrument in human and animal studies are given

  9. IAEA safeguards instrumentation: Development, implementation and control

    International Nuclear Information System (INIS)

    Rundquist, D.E.

    1983-01-01

    Extensive development efforts over the last 5 years have produced a number of new instruments to help the IAEA meet its safeguards obligations. Implementation of these new instruments is proceeding at a necessarily slower pace. To optimize the performance and reliability of the instrumentation systems when used in safeguards applications, increasing attention is needed to be spent on performance monitoring and control of the instruments. (author)

  10. Digital study of nuclear reactor instrument

    International Nuclear Information System (INIS)

    Lv Gongxiang; Yang Zhijun

    2006-01-01

    The paper introduces the design method of nuclear reactor's digital instrument developed by authors based on the AT89C52 single chip microcomputer. Also the instrument system hardware structure and software framework are given. The instrument apply DDC112 which is responsible for the measure of lower current. When designing the instrument system, anti-interference measure of software, especially hardware is considered seriously. (authors)

  11. A new Loan-Stock Financial Instrument

    OpenAIRE

    Morozovsky, Alexander; Narasimhan, Rajan; Kholodenko, Yuri

    2000-01-01

    A new financial instrument (a new kind of a loan) is introduced. The loan-stock instrument (LSI) combines fixed rate instruments (loans, etc.) with other financial instruments that have higher volatilities and returns (stocks, mutual funds, currencies, derivatives, options, etc.). This new loan depends on the value of underlying security (for example, stock) in such a way that when underlying security increases, the value of loan decreases and backwards. The procedure to create a risk free po...

  12. Marketing instruments of foreign trade promotion

    OpenAIRE

    Bjelić Predrag

    2011-01-01

    Instruments of promotion as a part of marketing mix are usually associated with companies but more and more countries use this instrument in order to boost their exports. These foreign trade promotion instruments are now popular in many countries in the world since their use is not opposed to any World Trade Organization rules. Marketing instruments of trade promotions are the most important. They include National Exhibitions and National labels of origin and quality. In order to coordinate t...

  13. Development on experimental VHTR instrumentation

    International Nuclear Information System (INIS)

    Wakayama, N.; Ara, K.; Terada, H.; Yamagishi, H.; Tomoda, T.

    1982-06-01

    This paper describes developmental works on the instrumentation of the Experimental VHTR. In the area of the nuclear instrumentation for the reactor control, high temperature fission counter-chambers have been developed. These withstood the accelerated irradiation life tests at 600 deg. C, the long term in-reactor operating test at 600 deg. C and the 800 deg. C-operating tests for several hundred hours in a simulated accident condition. Platinum-Molybdenum alloy thermocouples have been studied as a neutron-irradiation-resistant high-temperature thermocouple for the in-core temperature distribution monitoring of the VHTR in the temperature range between 1000 deg. C and 1350 deg. C. The instability problems of the Pt-5% Mo/Pt-0.1% Mo thermocouple seem to be overcome by introducing a double sheath structure and adopting a better material to the inner sheath. A local failure and abnormality monitoring method for the HTR fuel is also studied using a gas-sweeping irradiation rig for the CPF compacts. This study aims mainly at the development of a method to compensate for the dependency of the FP-release rate on the fuel temperature, the neutron flux density, the burn-up and others, in order to increase the detection sensitivity of fuel failures. (author)

  14. Economic instruments for waste management

    International Nuclear Information System (INIS)

    Malaman, R.

    1991-01-01

    Economic instruments for the implementation of environmental policies distinguish themselves from traditional tools (the 'command and control' type) for the reason that: they influence the costs and the benefits of the economic agents in question; they change the behaviour of the subjects in question in a way that they guarantee behaviour trends less harmful to the environment; they guarantee the assignment of adequate prices to the natural resources that traditionally don't have a price and therefore are consumed excessively by the economic subjects; normally they impose the transfer of economic resources to the disadvantage of the subjects responsible for the phenomena of pollution; certain objective pollution reduction data guarantee the minimization of the social costs of pollution abatement, that is, of the total costs on the economic system in general (economists define this characteristic as the 'static efficiency'); they guarantee what is called in economical jargon, the dynamic efficiency, i.e., in practice, they determine a continuous incentive for the reduction of the emission of the various pollutants and for the realization of the technological innovations that are able to control the pollution; they are more flexible than the instruments of direct regulation, because they leave the subjects a freedom of choice under different price conditions than in the past; they are flexible as well for the reason that the public operator can intervene rapidly to change the way of application

  15. Bicep2. III. INSTRUMENTAL SYSTEMATICS

    International Nuclear Information System (INIS)

    Ade, P. A. R.; Aikin, R. W.; Bock, J. J.; Brevik, J. A.; Filippini, J. P.; Golwala, S. R.; Hildebrandt, S. R.; Barkats, D.; Benton, S. J.; Bischoff, C. A.; Buder, I.; Karkare, K. S.; Bullock, E.; Dowell, C. D.; Duband, L.; Fliescher, S.; Halpern, M.; Hasselfield, M.; Hilton, G. C.; Irwin, K. D.

    2015-01-01

    In a companion paper, we have reported a >5σ detection of degree scale B-mode polarization at 150 GHz by the Bicep2 experiment. Here we provide a detailed study of potential instrumental systematic contamination to that measurement. We focus extensively on spurious polarization that can potentially arise from beam imperfections. We present a heuristic classification of beam imperfections according to their symmetries and uniformities, and discuss how resulting contamination adds or cancels in maps that combine observations made at multiple orientations of the telescope about its boresight axis. We introduce a technique, which we call “deprojection,” for filtering the leading order beam-induced contamination from time-ordered data, and show that it reduces power in Bicep2's actual and null-test BB spectra consistent with predictions using high signal-to-noise beam shape measurements. We detail the simulation pipeline that we use to directly simulate instrumental systematics and the calibration data used as input to that pipeline. Finally, we present the constraints on BB contamination from individual sources of potential systematics. We find that systematics contribute BB power that is a factor of ∼10× below Bicep2's three-year statistical uncertainty, and negligible compared to the observed BB signal. The contribution to the best-fit tensor/scalar ratio is at a level equivalent to r = (3–6) × 10 −3

  16. Bicep2. III. INSTRUMENTAL SYSTEMATICS

    Energy Technology Data Exchange (ETDEWEB)

    Ade, P. A. R. [School of Physics and Astronomy, Cardiff University, Cardiff, CF24 3AA (United Kingdom); Aikin, R. W.; Bock, J. J.; Brevik, J. A.; Filippini, J. P.; Golwala, S. R.; Hildebrandt, S. R. [Department of Physics, California Institute of Technology, Pasadena, CA 91125 (United States); Barkats, D. [Joint ALMA Observatory, ESO, Santiago (Chile); Benton, S. J. [Department of Physics, University of Toronto, Toronto, ON (Canada); Bischoff, C. A.; Buder, I.; Karkare, K. S. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street MS 42, Cambridge, MA 02138 (United States); Bullock, E. [Minnesota Institute for Astrophysics, University of Minnesota, Minneapolis, MN 55455 (United States); Dowell, C. D. [Jet Propulsion Laboratory, Pasadena, CA 91109 (United States); Duband, L. [SBT, Commissariat à l’Energie Atomique, Grenoble (France); Fliescher, S. [Department of Physics, University of Minnesota, Minneapolis, MN 55455 (United States); Halpern, M.; Hasselfield, M. [Department of Physics and Astronomy, University of British Columbia, Vancouver, BC (Canada); Hilton, G. C.; Irwin, K. D., E-mail: csheehy@uchicago.edu [National Institute of Standards and Technology, Boulder, CO 80305 (United States); Collaboration: Bicep2 Collaboration; and others

    2015-12-01

    In a companion paper, we have reported a >5σ detection of degree scale B-mode polarization at 150 GHz by the Bicep2 experiment. Here we provide a detailed study of potential instrumental systematic contamination to that measurement. We focus extensively on spurious polarization that can potentially arise from beam imperfections. We present a heuristic classification of beam imperfections according to their symmetries and uniformities, and discuss how resulting contamination adds or cancels in maps that combine observations made at multiple orientations of the telescope about its boresight axis. We introduce a technique, which we call “deprojection,” for filtering the leading order beam-induced contamination from time-ordered data, and show that it reduces power in Bicep2's actual and null-test BB spectra consistent with predictions using high signal-to-noise beam shape measurements. We detail the simulation pipeline that we use to directly simulate instrumental systematics and the calibration data used as input to that pipeline. Finally, we present the constraints on BB contamination from individual sources of potential systematics. We find that systematics contribute BB power that is a factor of ∼10× below Bicep2's three-year statistical uncertainty, and negligible compared to the observed BB signal. The contribution to the best-fit tensor/scalar ratio is at a level equivalent to r = (3–6) × 10{sup −3}.

  17. Instrument for measuring flow velocities

    International Nuclear Information System (INIS)

    Griffo, J.

    1977-01-01

    The design described here means to produce a 'more satisfying instrument with less cost' than comparable instruments known up to now. Instead of one single turbine rotor, two similar ones but with opposite blade inclination and sense of rotation are to be used. A cylindrical measuring body is carrying in its axis two bearing blocks whose shape is offering little flow resistance. On the shaft, supported by them, the two rotors run in opposite direction a relatively small axial distance apart. The speed of each rotor is picked up as pulse recurrence frequency by a transmitter and fed to an electronic measuring unit. Measuring errors as they are caused for single rotors by turbulent flow, profile distortion of the velocity, or viscous flow are to be eliminated by means of the contrarotating turbines and the subsequently added electronic unit, because in these cases the adulterating increase of the angular velocity of one rotor is compensated by a corresponding deceleration of the other rotor. The mean value then indicated by the electronic unit has high accurancy of measurement. (RW) [de

  18. PACMAN: PRIMA astrometric instrument software

    Science.gov (United States)

    Abuter, Roberto; Sahlmann, Johannes; Pozna, Eszter

    2010-07-01

    The dual feed astrometric instrument software of PRIMA (PACMAN) that is currently being integrated at the VLTI will use two spatially modulated fringe sensor units and a laser metrology system to carry out differential astrometry. Its software and hardware compromises a distributed system involving many real time computers and workstations operating in a synchronized manner. Its architecture has been designed to allow the construction of efficient and flexible calibration and observation procedures. In parallel, a novel scheme of integrating M-code (MATLAB/OCTAVE) with standard VLT (Very Large Telescope) control software applications had to be devised in order to support numerically intensive operations and to have the capacity of adapting to fast varying strategies and algorithms. This paper presents the instrument software, including the current operational sequences for the laboratory calibration and sky calibration. Finally, a detailed description of the algorithms with their implementation, both under M and C code, are shown together with a comparative analysis of their performance and maintainability.

  19. Tamper indicating radiation surveillance instrumentation

    International Nuclear Information System (INIS)

    Chambers, W.H.; Ney, J.F.

    1975-01-01

    Prototype personnel and shipping dock portal monitors suitable for unattended use were fabricated and tested. The requirement for continuous operation with only periodic inspection along with a desire for minimum costs and minimum interference with normal plant operation imposed unique design constraints. The design, operation, and performance of the detection and data recording instrumentation are described, as well as the tamper indicating techniques required to protect the collected data. The essential elements of either of the two instruments include a gamma detector array, signal conditioning electronics, digital alarm logic circuitry, power supplies, a microwave occupancy monitor, surveillance camera, irreversible electromechanical counters, and the appropriate tamper indicating envelope protecting these elements. Attempts to penetrate the tamper indicating envelope require material removal, and undetectable repair is very difficult, if not impossible. The techniques for joining major subassemblies and providing unique seals are also described. The personnel doorway uses a double pole array of NaI(Tl) detectors, and outputs are taken from a single channel pulse height analyzer with a window set at 60 to 250 keV and the lower level discriminator at greater than 60 keV. A sliding interval counter is used to make comparisons to an accumulated background at the 4sigma level. Logic design, sensitivity for special nuclear materials, false alarm data, and test procedures are described in detail. The shipping dock monitor had different design constraints and therefore uses a single, long, cylindrical plastic scintillator. Some differences in signal conditioning and processing are also described. (auth)

  20. Instrumentation for mass spectrometry: 1997

    Energy Technology Data Exchange (ETDEWEB)

    McLuckey, S.A.

    1997-08-01

    All mass spectrometry experiments involve the manipulation of material, an interface with the mass spectrometer, ionization, ion manipulation/analysis, detection and data collection/reduction. Each of these elements involve instrumentation. The wide range of species now amenable to mass spectrometry and the diverse areas of physical science in which it plays a role have led to a seemingly unlimited array of instrumental combinations. However, only a limited number of mass analyzers, and their combinations, dominate. The dominant analyzers include time-of-flight, Fourier transform ion cyclotron resonance, the Paul trap, the mass filter, and the sector mass spectrometer. Why there are so few (or so many, depending upon one`s point of view) can be understood upon consideration of a set of mass analyzer figures of merit. These include mass resolution, mass accuracy, mass range, dynamic range, abundance sensitivity, precision, efficiency, speed, MS{sup n} capability, compatibility with the ionizer, cost, and size. The most appropriate form of mass spectrometry is determined by the priorities of the particular measurement placed on the various mass analyzer characteristics and the relative strengths of the analyzers in meeting the requirements. Each of the analyzer types has a unique set of figures of merit that makes it optimally suited for particular applications. This paper discusses these figures of merit, provides data illustrating recent developments for each analyzer type, and gives the figures of merit of each type of analyzer as they stand in 1997. 101 refs., 24 figs.

  1. ICFA Instrumentation Bulletin, Volume 14, Spring 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    The publication of the ICFA Instrumentation Bulletin is an activity of the Panel on Future Innovation and Development of ICFA (International Committee for Future Accelerators). The Bulletin reports on research and progress in the field of instrumentation with emphasis on application in the field of high-energy physics. It encourages issues of generic instrumentation.

  2. The Squiggle: A Digital Musical Instrument

    OpenAIRE

    Sheehan, Brian

    2004-01-01

    This paper discusses some of the issues pertaining to thedesign of digital musical instruments that are to effectively fillthe role of traditional instruments (i.e. those based on physicalsound production mechanisms). The design andimplementation of a musical instrument that addresses some ofthese issues, using scanned synthesis coupled to a "smart"physical system, is described.

  3. Automated testing of health physics instruments

    International Nuclear Information System (INIS)

    Swinth, K.L.; Endres, A.W.; Hadley, R.T.; Kenoyer, J.L.

    1983-12-01

    A microcomputer controlled CAMAC system has been adapted for automated testing of health physics survey instruments. Once the survey instrument is positioned, the system automatically performs tests for angular dependence or battery lifetime. Rotation of the instrument is performed by a computer controlled stepping motor while readout is performed by an auto ranging digital volt meter and data stored on computer disks

  4. Report of the Instrumentation Service - Annex C

    International Nuclear Information System (INIS)

    Majstorovic, D.

    1987-01-01

    This report describes the tasks and organizational structure of the Instrumentation service. The most important task of this Service is control and maintenance of the reactor control and protection instruments, operation control, and dosimetry system. Besides data about this basic instrumentation, the report includes data about control and maintenance of other electronic equipment related to experimental facilities [sr

  5. Simulation tools for detector and instrument design

    DEFF Research Database (Denmark)

    Kanaki, Kalliopi; Kittelmann, Thomas; Cai, Xiao Xiao

    2018-01-01

    The high performance requirements at the European Spallation Source have been driving the technological advances on the neutron detector front. Now more than ever is it important to optimize the design of detectors and instruments, to fully exploit the ESS source brilliance. Most of the simulation...... a powerful set of tools to tailor the detector and instrument design to the instrument application....

  6. Are Musical Instrument Gender Associations Changing?

    Science.gov (United States)

    Abeles, Hal

    2009-01-01

    The researcher sought to examine gender associations across three decades to determine if changes in the sex stereotyping of musical instruments has occurred. First, the study examined the paired comparison gender-instrument rankings of 180 college students. The results confirmed a reduction of instrument gender associations reported in the 1990s.…

  7. Adult Perspectives of Learning Musical Instruments

    Science.gov (United States)

    Roulston, Kathryn; Jutras, Peter; Kim, Seon Joo

    2015-01-01

    This article reports findings from a qualitative study of adults' perceptions and experiences of learning musical instruments. Conducted in the south-east United States, 15 adults who were learning instruments were recruited via community music groups and private instrumental teachers. Analysis of transcripts of semi-structured interviews…

  8. The scientific use of technological instruments

    NARCIS (Netherlands)

    Boon, Mieke; Hansson, Sven Ove

    2015-01-01

    One of the most obvious ways in which the natural sciences depend on technology is through the use of instruments. This chapter presents a philosophical analysis of the role of technological instruments in science. Two roles of technological instruments in scientific practices are distinguished:

  9. Software-Enabled Modular Instrumentation Systems

    NARCIS (Netherlands)

    Soijer, M.W.

    2003-01-01

    Like most other types of instrumentation systems, flight test instrumentation is not produced in series; its development is a one-time achievement by a test department. With the introduction of powerful digital computers, instrumentation systems have included data analysis tasks that were previously

  10. Aspects of progress in neutron instrumentation

    International Nuclear Information System (INIS)

    Carlile, C.J.

    1999-01-01

    The capability of neutron instrumentation in coming years will depend upon many factors, the main ones being the neutron source the instrument is sited on, the quality of the instrument itself, the quality of the support provided and the protocol for instrument operation. All of these factors must be optimised and improved upon to ensure consistently high quality scientific exploitation of an instrument. Examples of progress in each of these fields are given and a subjective view of possible future trends are hazarded. (author)

  11. Advanced neutron instrumentation at FRM-II

    International Nuclear Information System (INIS)

    Petry, Winfried

    2003-01-01

    The construction of the new German high flux neutron source FRM-II is finished and FRM-II is waiting for its licence to start nuclear operation. With the beginning of the routine operation 22 instruments will be in action, including 5 irradiation facilities and 17 beam tube instruments, most of them use neutron scattering techniques. Additional instruments are under construction. Some of these instruments are unique, others are expected to be the best of their kind, all instruments are based on innovative techniques. (author)

  12. MITIGATING INNOVATION RISKS CONCERNING INTELLECTUAL PROPERTY INSTRUMENTS

    Directory of Open Access Journals (Sweden)

    Andreea DUMITRESCU

    2014-11-01

    Full Text Available As protection of innovation is possible using a variety of intellectual property instruments, the current paper aims at emphasizing the vulnerabilities of these instruments in order to facilitate the right choice in terms of protection, exploitation and dissemination of innovation. Based on a review of the intellectual property instruments and their related risk factors, the study identifies and formulates specific proactive strategies which arise from the fact that an instrument alone does not allow for effective protection, exploitation and dissemination and oftentimes the owners of innovation should combine traditional and alternative instruments. Therefore, the results of this analysis represent a helpful tool for managers in the decisional process.

  13. Smart instrumentation development at Los Alamos

    International Nuclear Information System (INIS)

    Erkkila, B.

    1984-01-01

    For several years Los Alamos has incorporated microprocessors into instruments to expand the capability of portable survey type equipment. Beginning with portable pulse height analyzers, the developments have expanded to small dedicated instruments which handle the measurement and interpretation of various radiation fields. So far, instruments to measure gamma rays, neutrons, and beta particles have been produced. The computer capability built into these instruments provides significant computational power into the instruments. Capability unheard of a few years ago in small portable instruments is routine today. Large computer-based laboratory measurement systems which required much space and electrical power can now be incorporated in a portable hand-held instrument. The microprocessor developments at Los Alamos are now restricted to radiation monitoring equipment but can be expanded to chemical and biological applications as well. Applications for radiation monitoring equipment and others are discussed

  14. The Choice of Innovation Policy Instruments

    DEFF Research Database (Denmark)

    Borrás, Susana; Edquist, Charles

    The purpose of this article is to discuss the different types of instruments of innovation policy, to examine how governments and public agencies in different countries and different times have used these instruments differently, to explore the political nature of instrument choice and design (and...... associated issues), and to elaborate a set of criteria for the selection and design of the instruments in relation to the formulation of innovation policy. The article argues that innovation policy instruments must be designed and combined into mixes in ways that address the problems of the innovation system....... These mixes are often called “policy mix”. The problem-oriented nature of the design of instrument mixes is what makes innovation policy instruments ‘systemic’....

  15. The Choice of Innovation Policy Instruments

    DEFF Research Database (Denmark)

    Borrás, Susana; Edquist, Charles

    2013-01-01

    The purpose of this article is to discuss the different types of instruments of innovation policy, to examine how governments and public agencies in different countries and different times have used these instruments differently, to explore the political nature of instrument choice and design (and...... associated issues), and to elaborate a set of criteria for the selection and design of the instruments in relation to the formulation of innovation policy. The article argues that innovation policy instruments must be designed and combined into mixes in ways that address the problems of the innovation system....... These mixes are often called “policy mix”. The problem-oriented nature of the design of instrument mixes is what makes innovation policy instruments ‘systemic’....

  16. Asteroid electrostatic instrumentation and modelling

    Energy Technology Data Exchange (ETDEWEB)

    Aplin, K L; Bowles, N E; Urbak, E [Department of Physics, University of Oxford, Denys Wilkinson Building, Keble Road, Oxford OX1 3RH (United Kingdom); Keane, D; Sawyer, E C, E-mail: k.aplin1@physics.ox.ac.uk [RAL Space, R25, Harwell Oxford, Didcot OX11 0QX (United Kingdom)

    2011-06-23

    Asteroid surface material is expected to become photoelectrically charged, and is likely to be transported through electrostatic levitation. Understanding any movement of the surface material is relevant to proposed space missions to return samples to Earth for detailed isotopic analysis. Motivated by preparations for the Marco Polo sample return mission, we present electrostatic modelling for a real asteroid, Itokawa, for which detailed shape information is available, and verify that charging effects are likely to be significant at the terminator and at the edges of shadow regions for the Marco Polo baseline asteroid, 1999JU3. We also describe the Asteroid Charge Experiment electric field instrumentation intended for Marco Polo. Finally, we find that the differing asteroid and spacecraft potentials on landing could perturb sample collection for the short landing time of 20min that is currently planned.

  17. Nuclear reactor instrumentation power monitor

    International Nuclear Information System (INIS)

    Suzuki, Shigeru.

    1989-01-01

    The present invention concerns a nuclear reactor instrumentation power monitor that can be used in, for example, BWR type nuclear power plants. Signals from multi-channel detectors disposed on field units are converted respectively by LPRM signal circuits. Then, the converted signals are further converted by a multiplexer into digital signals and transmitted as serial data to a central monitor unit. The thus transmitted serial data are converted into parallel data in the signal processing section of the central monitor unit. Then, LPRM signals are taken out from each of channel detectors to conduct mathematical processing such as trip judgment or averaging. Accordingly, the field unit and the central monitor unit can be connected by way of only one data transmission cable thereby enabling to reduce the number of cables. Further, since the data are transmitted on digital form, it less undergoes effect of noises. (I.S.)

  18. Anàlisi instrumental

    OpenAIRE

    Casas Sabata, Josep M.

    1994-01-01

    Conté: 2. Cromatografia i electroforesi Aquest text pretén donar una visió general de l'ampli camp dels mètodes instrumentals de separació aplicats al laboratori d'anàlis segons un concepte eminentment pràctic. S'ha dividit en cinc capítols temàtics: teoria de la cromatografia, cromatografia clàssica, cromatografia de gasos, cromatografia de líquids i electroforesi. Va destinat als estudiants d'enginyeria i de les facultats de ciències que dins el seu pla d'estudis incorporin la matèria d'...

  19. Presentation of a new instrument

    DEFF Research Database (Denmark)

    Russell, M B; Rasmussen, B K; Brennum, J

    1992-01-01

    A new instrument, the Diagnostic Headache Diary, based on the operational diagnostic criteria of the International Headache Society (IHS), was tested in 61 migraine patients from a headache research clinic using the clinical diagnosis (IHS criteria) for comparison. All patients kept the diary...... for one to eight months. The clinical and diary diagnosis of migraine with and without aura was the same in, respectively, 72 and 87% of the patients. Nausea, photophobia and phonophobia tended to be more pronounced at the clinical interview. The diary identified 20 more cases of episodic tension......-type headache and 15 fewer cases of chronic tension-type headache than the clinical interview. Two blinded observers always made the same IHS diagnoses when interpreting the diagnostic headache diary. A combination of a clinical interview and the diagnostic headache diary gives a qualitatively...

  20. Application of Fiber Optic Instrumentation

    Science.gov (United States)

    Richards, William Lance; Parker, Allen R., Jr.; Ko, William L.; Piazza, Anthony; Chan, Patrick

    2012-01-01

    Fiber optic sensing technology has emerged in recent years offering tremendous advantages over conventional aircraft instrumentation systems. The advantages of fiber optic sensors over their conventional counterparts are well established; they are lighter, smaller, and can provide enormous numbers of measurements at a fraction of the total sensor weight. After a brief overview of conventional and fiber-optic sensing technology, this paper presents an overview of the research that has been conducted at NASA Dryden Flight Research Center in recent years to advance this promising new technology. Research and development areas include system and algorithm development, sensor characterization and attachment, and real-time experimentally-derived parameter monitoring for ground- and flight-based applications. The vision of fiber optic smart structure technology is presented and its potential benefits to aerospace vehicles throughout the lifecycle, from preliminary design to final retirement, are presented.

  1. Forward instrumentation for ILC detectors

    International Nuclear Information System (INIS)

    Abramowicz, Halina; Abusleme, Angel; Afanaciev, Konstantin

    2010-09-01

    Two special calorimeters are foreseen for the instrumentation of the very forward region of the ILC detector, a luminometer designed to measure the rate of low angle Bhabha scattering events with a precision better than 10 -3 and a low polar angle calorimeter, adjacent to the beam-pipe. The latter will be hit by a large amount of beamstrahlung remnants. The amount and shape of these depositions will allow a fast luminosity estimate and the determination of beam parameters. The sensors of this calorimeter must be radiation hard. Both devices will improve the hermeticity of the detector in the search for new particles. Finely segmented and very compact calorimeters will match the requirements. Due to the high occupancy fast front-end electronics is needed. The design of the calorimeters developed and optimised with Monte Carlo simulations is presented. Sensors and readout electronics ASICs have been designed and prototypes are available. Results on the performance of these major components are summarised. (orig.)

  2. The Bering Target Tracking Instrumentation

    DEFF Research Database (Denmark)

    Denver, Troelz; Jørgensen, John Leif; Betto, Maurizio

    2003-01-01

    The key science instrument on the Bering satellite mission is a relative small telescope with an entrance aperture of 300 mm and a focal length between 500 and 1000 mm. The detection of potential targets is performed by one of the target scanning advanced stellar compasses (ASCs). This procedure...... results in a simple prioritized list of right ascension, declination, proper motion and intensity of each prospective target. The telescope itself has a dedicated ASC Camera Head Unit (CHU) mounted on the secondary mirror, largely co-aligned with the telescope. This CHU accurately determines the telescope......'s pointing direction. To achieve fast tracking over a large solid angle, the telescope pointing is achieved by means of a folding mirror in the optical pathway. When a prospective target approaches the telescope FOV, the ASC on the secondary will guide the folding mirror into position such that the target...

  3. Online Personalization of Hearing Instruments

    Directory of Open Access Journals (Sweden)

    Bert de Vries

    2008-09-01

    Full Text Available Online personalization of hearing instruments refers to learning preferred tuning parameter values from user feedback through a control wheel (or remote control, during normal operation of the hearing aid. We perform hearing aid parameter steering by applying a linear map from acoustic features to tuning parameters. We formulate personalization of the steering parameters as the maximization of an expected utility function. A sparse Bayesian approach is then investigated for its suitability to find efficient feature representations. The feasibility of our approach is demonstrated in an application to online personalization of a noise reduction algorithm. A patient trial indicates that the acoustic features chosen for learning noise control are meaningful, that environmental steering of noise reduction makes sense, and that our personalization algorithm learns proper values for tuning parameters.

  4. Forward Instrumentation for ILC Detectors

    CERN Document Server

    Abramowicz, Halina; Afanaciev, Konstantin; Aguilar, Jonathan; Ambalathankandy, Prasoon; Bambade, Philip; Bergholz, Matthias; Bozovic-Jelisavcic, Ivanka; Castro, Elena; Chelkov, Georgy; Coca, Cornelia; Daniluk, Witold; Dragone, Angelo; Dumitru, Laurentiu; Elsener, Konrad; Emeliantchik, Igor; Fiutowski, Tomasz; Gostkin, Mikhail; Grah, Christian; Grzelak, Grzegorz; Haller, Gunter; Henschel, Hans; Ignatenko, Alexandr; Idzik, Marek; Ito, Kazutoshi; Jovin, Tatjana; Kielar, Eryk; Kotula, Jerzy; Krumstein, Zinovi; Kulis, Szymon; Lange, Wolfgang; Lohmann, Wolfgang; Levy, Aharon; Moszczynski, Arkadiusz; Nauenberg, Uriel; Novgorodova, Olga; Ohlerich, Marin; Orlandea, Marius; Oleinik, Gleb; Oliwa, Krzysztof; Olshevski, Alexander; Pandurovic, Mila; Pawlik, Bogdan; Przyborowski, Dominik; Sato, Yutaro; Sadeh, Iftach; Sailer, Andre; Schmidt, Ringo; Schumm, Bruce; Schuwalow, Sergey; Smiljanic, Ivan; Swientek, Krzysztof; Takubo, Yosuke; Teodorescu, Eliza; Wierba, Wojciech; Yamamoto, Hitoshi; Zawiejski, Leszek; Zhang, Jinlong

    2010-01-01

    Two special calorimeters are foreseen for the instrumentation of the very forward region of the ILC detector, a luminometer designed to measure the rate of low angle Bhabha scattering events with a precision better than 10-3 and a low polar angle calorimeter, adjacent to the beam-pipe. The latter will be hit by a large amount of beamstrahlung remnants. The amount and shape of these depositions will allow a fast luminosity estimate and the determination of beam parameters. The sensors of this calorimeter must be radiation hard. Both devices will improve the hermeticity of the detector in the search for new particles. Finely segmented and very compact calorimeters will match the requirements. Due to the high occupancy fast front-end electronics is needed. The design of the calorimeters developed and optimised with Monte Carlo simulations is presented. Sensors and readout electronics ASICs have been designed and prototypes are available. Results on the performance of these major components are summarised.

  5. The Atacama Cosmology Telescope: Instrument

    Science.gov (United States)

    Thornton, Robert J.; Atacama Cosmology Telescope Team

    2010-01-01

    The 6-meter Atacama Cosmology Telescope (ACT) is making detailed maps of the Cosmic Microwave Background at Cerro Toco in northern Chile. In this talk, I focus on the design and operation of the telescope and its commissioning instrument, the Millimeter Bolometer Array Camera. The camera contains three independent sets of optics that operate at 148 GHz, 217 GHz, and 277 GHz with arcminute resolution, each of which couples to a 1024-element array of Transition Edge Sensor (TES) bolometers. I will report on the camera performance, including the beam patterns, optical efficiencies, and detector sensitivities. Under development for ACT is a new polarimeter based on feedhorn-coupled TES devices that have improved sensitivity and are planned to operate at 0.1 K.

  6. Industrial Products for Beam Instrumentation

    CERN Document Server

    Schmickler, Hermann

    2001-01-01

    In various branches of high technology industry there has been considerable progress in the past years which could be used for beam instrumentation. The subject will be introduced by two short demonstrations: a demonstration of modern audio electronics with 24bit-96kHz ADC, digital signal electronics and application programs under windows on a PC, which allow to change the parameters of the signal treatment. Potential applications are data monitoring at constant sampling frequency, orbit feedbacks (including high power audio amplifiers), noise reduction on beam current transformers... digital treatment of video signals webcams, frame grabbers, CCD-data via USB, all one needs for image acquisitions, in particular interesting for profile measurements. These introductory demonstrations will not last longer than 30 minutes. The remaining time will be used to pass through the audience collecting information into a two dimensional table, which shall contain as row index the accelerator and as column index the t...

  7. EPRI instruments reach commercial market

    International Nuclear Information System (INIS)

    Anon.

    1978-01-01

    The Electric Power Research Institute has developed instruments capable of verifying time responses of power plant pressure sensors and temperature sensors. A patent is pending on the pressure-sensor device, and the temperature-sensor device is already commercially available. The devices, EPRI's first hardware products to be marketed, are the result of research to find technological solutions to the problems of knowing the time period when temperature and pressure changes occur in light water reactors. The hydraulic pressure-sensor device is a portable unit that can conveniently test equipment in place. Utilities can obtain detailed information from EPRI's project report to construct their own. The loop current step response (LCSR), measuring resistance temperature, is also a compact system suitable for in-plant testing

  8. Laparoscopic splenectomy using conventional instruments

    Directory of Open Access Journals (Sweden)

    Dalvi A

    2005-01-01

    Full Text Available INTRODUCTION : Laparoscopic splenectomy (LS is an accepted procedure for elective splenectomy. Advancement in technology has extended the possibility of LS in massive splenomegaly [Choy et al., J Laparoendosc Adv Surg Tech A 14(4, 197-200 (2004], trauma [Ren et al., Surg Endosc 15(3, 324 (2001; Mostafa et al., Surg Laparosc Endosc Percutan Tech 12(4, 283-286 (2002], and cirrhosis with portal hypertension [Hashizume et al., Hepatogastroenterology 49(45, 847-852 (2002]. In a developing country, these advanced gadgets may not be always available. We performed LS using conventional and reusable instruments in a public teaching the hospital without the use of the advanced technology. The technique of LS and the outcome in these patients is reported. MATERIALS AND METHODS : Patients undergoing LS for various hematological disorders from 1998 to 2004 were included. Electrocoagulation, clips, and intracorporeal knotting were the techniques used for tackling short-gastric vessels and splenic pedicle. Specimen was delivered through a Pfannensteil incision. RESULTS : A total of 26 patients underwent LS. Twenty-two (85% of patients had spleen size more than 500 g (average weight being 942.55 g. Mean operative time was 214 min (45-390 min. The conversion rate was 11.5% ( n = 3. Average duration of stay was 5.65 days (3-30 days. Accessory spleen was detected and successfully removed in two patients. One patient developed subphrenic abscess. There was no mortality. There was no recurrence of hematological disease. CONCLUSION : Laparoscopic splenectomy using conventional equipment and instruments is safe and effective. Advanced technology has a definite advantage but is not a deterrent to the practice of LS.

  9. MC and A instrumentation catalog

    International Nuclear Information System (INIS)

    Neymotin, L.; Sviridova, V.

    1998-01-01

    In 1981 and 1985, two editions of a catalog of non-destructive nuclear measurement instrumentation, and material control and surveillance equipment, were published by Brookhaven National Laboratory (BNL). The last edition of the catalog included one hundred and twenty-five entries covering a wide range of devices developed in the US and abroad. More than ten years have elapsed since the publication of the more recent Catalog. Devices described in it have undergone significant modifications, and new devices have been developed. Therefore, in order to assist specialists in the field of Material Control and Accounting (MC and A), a new catalog has been created. Work on this instrumentation catalog started in 1997 as a cooperative effort of Brookhaven National Laboratory (BNL), operated by Brookhaven Science Associates under contract to the US Department of Energy, and the All-Russian Research Institute of Automatics (VNIIA), subordinate institute of the Atomic Energy Ministry of the Russian Federation, within the collaborative US-Russia Material Protection, Control, and Accounting (MPC and A) Program. Most of the equipment included in the Catalog are non-destructive assay (NDA) measurement devices employed for purposes of accounting, confirmation, and verification of nuclear materials. Other devices also included in the Catalog are employed in the detection and deterrence of unauthorized access to or removal of nuclear materials (material control: containment and surveillance). Equipment found in the Catalog comprises either: (1) complete devices or systems that can be used for MC and A applications; or (2) parts or components of complete systems, such as multi-channel analyzers, detectors, neutron generators, and software. All devices are categorized by their status of development--from prototype to serial production

  10. MC and A instrumentation catalog

    Energy Technology Data Exchange (ETDEWEB)

    Neymotin, L. [ed.] [Brookhaven National Lab., Upton, NY (United States); Sviridova, V. [ed.] [All-Russian Research Inst. of Automatics, Moscow (Russian Federation)

    1998-06-01

    In 1981 and 1985, two editions of a catalog of non-destructive nuclear measurement instrumentation, and material control and surveillance equipment, were published by Brookhaven National Laboratory (BNL). The last edition of the catalog included one hundred and twenty-five entries covering a wide range of devices developed in the US and abroad. More than ten years have elapsed since the publication of the more recent Catalog. Devices described in it have undergone significant modifications, and new devices have been developed. Therefore, in order to assist specialists in the field of Material Control and Accounting (MC and A), a new catalog has been created. Work on this instrumentation catalog started in 1997 as a cooperative effort of Brookhaven National Laboratory (BNL), operated by Brookhaven Science Associates under contract to the US Department of Energy, and the All-Russian Research Institute of Automatics (VNIIA), subordinate institute of the Atomic Energy Ministry of the Russian Federation, within the collaborative US-Russia Material Protection, Control, and Accounting (MPC and A) Program. Most of the equipment included in the Catalog are non-destructive assay (NDA) measurement devices employed for purposes of accounting, confirmation, and verification of nuclear materials. Other devices also included in the Catalog are employed in the detection and deterrence of unauthorized access to or removal of nuclear materials (material control: containment and surveillance). Equipment found in the Catalog comprises either: (1) complete devices or systems that can be used for MC and A applications; or (2) parts or components of complete systems, such as multi-channel analyzers, detectors, neutron generators, and software. All devices are categorized by their status of development--from prototype to serial production.

  11. Hybrid microcircuits for nuclear instrumentation

    International Nuclear Information System (INIS)

    Kulkarni, R.G.

    2005-01-01

    Hybrid microcircuits (HMCs) have distinct advantages over their rival products like printed circuit boards (PCBs) and integrated circuits (ICs), and are able to survive the onslaught of Moore's law, by retaining the niche market for themselves. The ASIC development cost is normally huge and when the volumes are small (less than ten thousand or so), the prohibitively high unit cost deters the potential customers. However the HMCs can be developed at a small fraction of an ASIC development cost and thus they are attractive when the volumes are small, as in the case of professional electronics industries like defense, broadcast, or instrumentation industries. The hybrid microcircuit (HMC) technology can involve one of the two processes: thick-film and thin- film. Broadly the thick-film process consists of printing and firing of, conductor and resistor pastes, on an Alumina substrate. The thin-film process consists of photo lithographic etching of, conductor and resistor patterns, on a metal/resistor sputtered high purity Alumina substrate. The active devices, either in die-form or in surface-mount form, are attached to the thick-film or the thin-film substrate. The passive devices like chip inductors and chip capacitors are also attached to the substrate. This paper discusses in detail the thick-film and the thin-film processes and their relative merits and demerits. The associated qualification and screening procedures followed to provide reliable HMCs to the customer are described. The existing HMC facilities and the product range available in Bharat Electronics including the HMCs developed for nuclear instrumentation are presented. (author)

  12. Origins, transformations and key foci in instrumental genesis

    DEFF Research Database (Denmark)

    Tamborg, Andreas Lindenskov

    This paper investigates the origins of the instrumental genesis and instrumental orchestrations frameworks. This is done by reviewing instrumented activity situations, instrumental genesis, and instrumental orchestrations with the purpose of identifying their epistemological assumptions, what the...... and instrumental orchestrations have potential shortcomings since the technologies that currently exist in school contexts are rather different from the technologies instrumental genesis was originally developed to study.......This paper investigates the origins of the instrumental genesis and instrumental orchestrations frameworks. This is done by reviewing instrumented activity situations, instrumental genesis, and instrumental orchestrations with the purpose of identifying their epistemological assumptions, what...

  13. Instrumentation for Sodium Circuits; Instrumentation des Circuits de Sodium

    Energy Technology Data Exchange (ETDEWEB)

    Cambillard, E. [CEA, Centre d' Etudes Nucleaires de Fontenay-aux-Roses (France); Lions, N. [CEA, Centre d' Etudes Nucleaires de Cadarache (France)

    1967-06-15

    Electromagnetic flow meters, level gauges and differential pressure gauges are among the main measurement instruments designed and tested at the Commissariat a l'Energie Atomique (CEA) for sodium reactors. The main characteristics of the flow meters used with RAPSODIE are indicated. The instruments used in this connection are of the permanent -magnet or electromagnet type (in the primary circuits). A description is given of the calibration methods employed - use is made of diaphragms or Venturi tubes as standard flow meters - and information is given on the results measured for maximum sodium flows of 400 m{sup 3}/h. Three types of continuous level gauge have been studied. Resistance gauge. Two varieties used for the 1 - and 10-MW test circuits of RAPSODIE are described. In one there is a compensation resistance along the whole height of the measuring element (the continuous gauges used with the RAPSODIE reactor are at present of this type). In the other type of gauge a device is incorporated to heat the measurement element and prevent the formation of conducting deposits (prototype sodium tests have been completed). Induction gauge. This type has two coupled coils and is fitted with a device to compensate for temperature effects. A description is given of a prototype which has been built and the results obtained in the course of sodium tests are described. Ultrasonic gauge. With this type, a transmitter is fitted on top of the outside of the sodium container; there is also a vertical wave guide, the bottom of which is immersed in the liquid metal and possesses a reflector system which returns the ultrasonic beam towards the surface. Fixed reference marks provide a permanent means of calibration and the whole apparatus is welded. This type of gauge is now being constructed. The differential pressure gauges that have been built, and used in particular with Venturi tube flow meters, are modified versions of the devices employed with the 1 - and 10-MW test circuits of

  14. Operational and reliability experience with reactor instrumentation

    International Nuclear Information System (INIS)

    Dixon, F.; Gow, R.S.

    1978-01-01

    In the last 15 years the CEGB has experienced progressive plant development, integration and changes in operating regime through nine nuclear (gas-cooled reactor) power stations with corresponding instrumentation advances leading towards more refined centralized control. Operation and reliability experience with reactor instrumentation is reported in this paper with reference to the progressive changes related to the early magnox, late magnox and AGR periods. Data on instrumentation reliability in terms of reactor forced outages are presented and show that the instrumentation contributions to loss of generating plant availability are small. Reactor safety circuits, neutron flux and temperature measurements, gas analysis and vibration monitoring are discussed. In reviewing the reactor instrumentation the emphasis is on reporting recent experience, particularly on AGR equipment, but overall performance and changes to magnox equipment are included so that some appreciation can be obtained of instrumentation requirements with respect to plant lifetimes. (author)

  15. Recent advances in radiation protection instrumentation

    International Nuclear Information System (INIS)

    Babu, D.A.R.

    2012-01-01

    Radiation protection instrumentation plays very important role in radiation protection and surveillance programme. Radiation detector, which appears at the frontal end of the instrument, is an essential component of these instruments. The instrumental requirement of protection level radiation monitoring is different from conventional radiation measuring instruments. Present paper discusses the new type of nuclear radiation detectors, new protection level instruments and associated electronic modules for various applications. Occupational exposure to ionizing radiation can occur in a range of industries, such as nuclear power plants; mining and milling; medical institutions; educational and research establishments; and nuclear fuel cycle facilities. Adequate radiation protection to workers is essential for the safe and acceptable use of radioactive materials for different applications. The radiation exposures to the individual radiation workers and records of their cumulative radiation doses need to be routinely monitored and recorded

  16. The JEM-EUSO instrument

    Science.gov (United States)

    Adams, J. H.; Ahmad, S.; Albert, J.-N.; Allard, D.; Anchordoqui, L.; Andreev, V.; Anzalone, A.; Arai, Y.; Asano, K.; Ave Pernas, M.; Baragatti, P.; Barrillon, P.; Batsch, T.; Bayer, J.; Bechini, R.; Belenguer, T.; Bellotti, R.; Belov, K.; Berlind, A. A.; Bertaina, M.; Biermann, P. L.; Biktemerova, S.; Blaksley, C.; Blanc, N.; Błȩcki, J.; Blin-Bondil, S.; Blümer, J.; Bobik, P.; Bogomilov, M.; Bonamente, M.; Briggs, M. S.; Briz, S.; Bruno, A.; Cafagna, F.; Campana, D.; Capdevielle, J.-N.; Caruso, R.; Casolino, M.; Cassardo, C.; Castellinic, G.; Catalano, C.; Catalano, G.; Cellino, A.; Chikawa, M.; Christl, M. J.; Cline, D.; Connaughton, V.; Conti, L.; Cordero, G.; Crawford, H. J.; Cremonini, R.; Csorna, S.; Dagoret-Campagne, S.; de Castro, A. J.; De Donato, C.; de la Taille, C.; De Santis, C.; del Peral, L.; Dell'Oro, A.; De Simone, N.; Di Martino, M.; Distratis, G.; Dulucq, F.; Dupieux, M.; Ebersoldt, A.; Ebisuzaki, T.; Engel, R.; Falk, S.; Fang, K.; Fenu, F.; Fernández-Gómez, I.; Ferrarese, S.; Finco, D.; Flamini, M.; Fornaro, C.; Franceschi, A.; Fujimoto, J.; Fukushima, M.; Galeotti, P.; Garipov, G.; Geary, J.; Gelmini, G.; Giraudo, G.; Gonchar, M.; González Alvarado, C.; Gorodetzky, P.; Guarino, F.; Guzmán, A.; Hachisu, Y.; Harlov, B.; Haungs, A.; Hernández Carretero, J.; Higashide, K.; Ikeda, D.; Ikeda, H.; Inoue, N.; Inoue, S.; Insolia, A.; Isgrò, F.; Itow, Y.; Joven, E.; Judd, E. G.; Jung, A.; Kajino, F.; Kajino, T.; Kaneko, I.; Karadzhov, Y.; Karczmarczyk, J.; Karus, M.; Katahira, K.; Kawai, K.; Kawasaki, Y.; Keilhauer, B.; Khrenov, B. A.; Kim, J.-S.; Kim, S.-W.; Kim, S.-W.; Kleifges, M.; Klimov, P. A.; Kolev, D.; Kreykenbohm, I.; Kudela, K.; Kurihara, Y.; Kusenko, A.; Kuznetsov, E.; Lacombe, M.; Lachaud, C.; Lee, J.; Licandro, J.; Lim, H.; López, F.; Maccarone, M. C.; Mannheim, K.; Maravilla, D.; Marcelli, L.; Marini, A.; Martinez, O.; Masciantonio, G.; Mase, K.; Matev, R.; Medina-Tanco, G.; Mernik, T.; Miyamoto, H.; Miyazaki, Y.; Mizumoto, Y.; Modestino, G.; Monaco, A.; Monnier-Ragaigne, D.; Morales de los Ríos, J. A.; Moretto, C.; Morozenko, V. S.; Mot, B.; Murakami, T.; Murakami, M. Nagano; Nagata, M.; Nagataki, S.; Nakamura, T.; Napolitano, T.; Naumov, D.; Nava, R.; Neronov, A.; Nomoto, K.; Nonaka, T.; Ogawa, T.; Ogio, S.; Ohmori, H.; Olinto, A. V.; Orleański, P.; Osteria, G.; Panasyuk, M. I.; Parizot, E.; Park, I. H.; Park, H. W.; Pastircak, B.; Patzak, T.; Paul, T.; Pennypacker, C.; Perez Cano, S.; Peter, T.; Picozza, P.; Pierog, T.; Piotrowski, L. W.; Piraino, S.; Plebaniak, Z.; Pollini, A.; Prat, P.; Prévôt, G.; Prieto, H.; Putis, M.; Reardon, P.; Reyes, M.; Ricci, M.; Rodríguez, I.; Rodríguez Frías, M. D.; Ronga, F.; Roth, M.; Rothkaehl, H.; Roudil, G.; Rusinov, I.; Rybczyński, M.; Sabau, M. D.; Sáez-Cano, G.; Sagawa, H.; Saito, A.; Sakaki, N.; Sakata, M.; Salazar, H.; Sánchez, S.; Santangelo, A.; Santiago Crúz, L.; Sanz Palomino, M.; Saprykin, O.; Sarazin, F.; Sato, H.; Sato, M.; Schanz, T.; Schieler, H.; Scotti, V.; Segreto, A.; Selmane, S.; Semikoz, D.; Serra, M.; Sharakin, S.; Shibata, T.; Shimizu, H. M.; Shinozaki, K.; Shirahama, T.; Siemieniec-Oziȩbło, G.; Silva López, H. H.; Sledd, J.; Słomińska, K.; Sobey, A.; Sugiyama, T.; Supanitsky, D.; Suzuki, M.; Szabelska, B.; Szabelski, J.; Tajima, F.; Tajima, N.; Tajima, T.; Takahashi, Y.; Takami, H.; Takeda, M.; Takizawa, Y.; Tenzer, C.; Tibolla, O.; Tkachev, L.; Tokuno, H.; Tomida, T.; Tone, N.; Toscano, S.; Trillaud, F.; Tsenov, R.; Tsunesada, Y.; Tsuno, K.; Tymieniecka, T.; Uchihori, Y.; Unger, M.; Vaduvescu, O.; Valdés-Galicia, J. F.; Vallania, P.; Valore, L.; Vankova, G.; Vigorito, C.; Villaseñor, L.; von Ballmoos, P.; Wada, S.; Watanabe, J.; Watanabe, S.; Watts, J.; Weber, M.; Weiler, T. J.; Wibig, T.; Wiencke, L.; Wille, M.; Wilms, J.; Włodarczyk, Z.; Yamamoto, T.; Yamamoto, Y.; Yang, J.; Yano, H.; Yashin, I. V.; Yonetoku, D.; Yoshida, K.; Yoshida, S.; Young, R.; Zotov, M. Yu.; Zuccaro Marchi, A.

    2015-11-01

    In this paper we describe the main characteristics of the JEM-EUSO instrument. The Extreme Universe Space Observatory on the Japanese Experiment Module (JEM-EUSO) of the International Space Station (ISS) will observe Ultra High-Energy Cosmic Rays (UHECR) from space. It will detect UV-light of Extensive Air Showers (EAS) produced by UHECRs traversing the Earth's atmosphere. For each event, the detector will determine the energy, arrival direction and the type of the primary particle. The advantage of a space-borne detector resides in the large field of view, using a target volume of about 1012 tons of atmosphere, far greater than what is achievable from ground. Another advantage is a nearly uniform sampling of the whole celestial sphere. The corresponding increase in statistics will help to clarify the origin and sources of UHECRs and characterize the environment traversed during their production and propagation. JEM-EUSO is a 1.1 ton refractor telescope using an optics of 2.5 m diameter Fresnel lenses to focus the UV-light from EAS on a focal surface composed of about 5,000 multi-anode photomultipliers, for a total of ≃3ṡ105 channels. A multi-layer parallel architecture handles front-end acquisition, selecting and storing valid triggers. Each processing level filters the events with increasingly complex algorithms using FPGAs and DSPs to reject spurious events and reduce the data rate to a value compatible with downlink constraints.

  17. Human pavlovian-instrumental transfer.

    Science.gov (United States)

    Talmi, Deborah; Seymour, Ben; Dayan, Peter; Dolan, Raymond J

    2008-01-09

    The vigor with which a participant performs actions that produce valuable outcomes is subject to a complex set of motivational influences. Many of these are believed to involve the amygdala and the nucleus accumbens, which act as an interface between limbic and motor systems. One prominent class of influences is called pavlovian-instrumental transfer (PIT), in which the motivational characteristics of a predictor influence the vigor of an action with respect to which it is formally completely independent. We provide a demonstration of behavioral PIT in humans, with an audiovisual predictor of the noncontingent delivery of money inducing participants to perform more avidly an action involving squeezing a handgrip to earn money. Furthermore, using functional magnetic resonance imaging, we show that this enhanced motivation was associated with a trial-by-trial correlation with the blood oxygenation level-dependent (BOLD) signal in the nucleus accumbens and a subject-by-subject correlation with the BOLD signal in the amygdala. Our data dovetails well with the animal literature and sheds light on the neural control of vigor.

  18. Human Pavlovian–Instrumental Transfer

    Science.gov (United States)

    Talmi, Deborah; Seymour, Ben; Dayan, Peter; Dolan, Raymond J.

    2009-01-01

    The vigor with which a participant performs actions that produce valuable outcomes is subject to a complex set of motivational influences. Many of these are believed to involve the amygdala and the nucleus accumbens, which act as an interface between limbic and motor systems. One prominent class of influences is called pavlovian–instrumental transfer (PIT), in which the motivational characteristics of a predictor influence the vigor of an action with respect to which it is formally completely independent. We provide a demonstration of behavioral PIT in humans, with an audiovisual predictor of the noncontingent delivery of money inducing participants to perform more avidly an action involving squeezing a handgrip to earn money. Furthermore, using functional magnetic resonance imaging, we show that this enhanced motivation was associated with a trial-by-trial correlation with the blood oxygenation level-dependent (BOLD) signal in the nucleus accumbens and a subject-by-subject correlation with the BOLD signal in the amygdala. Our data dovetails well with the animal literature and sheds light on the neural control of vigor. PMID:18184778

  19. Forward instrumentation for ILC detectors

    Energy Technology Data Exchange (ETDEWEB)

    Abramowicz, Halina [Tel Aviv Univ. (Israel); Abusleme, Angel [Stanford Univ., CA (United States); Afanaciev, Konstantin [NCPHEP, Minsk (BY)] (and others)

    2010-09-15

    Two special calorimeters are foreseen for the instrumentation of the very forward region of the ILC detector, a luminometer designed to measure the rate of low angle Bhabha scattering events with a precision better than 10{sup -3} and a low polar angle calorimeter, adjacent to the beam-pipe. The latter will be hit by a large amount of beamstrahlung remnants. The amount and shape of these depositions will allow a fast luminosity estimate and the determination of beam parameters. The sensors of this calorimeter must be radiation hard. Both devices will improve the hermeticity of the detector in the search for new particles. Finely segmented and very compact calorimeters will match the requirements. Due to the high occupancy fast front-end electronics is needed. The design of the calorimeters developed and optimised with Monte Carlo simulations is presented. Sensors and readout electronics ASICs have been designed and prototypes are available. Results on the performance of these major components are summarised. (orig.)

  20. LISA Pathfinder instrument data analysis

    Science.gov (United States)

    Guzman, Felipe

    LISA Pathfinder (LPF) is an ESA-launched demonstration mission of key technologies required for the joint NASA-ESA gravitational wave observatory in space, LISA. As part of the LPF interferometry investigations, analytic models of noise sources and corresponding noise subtrac-tion techniques have been developed to correct for effects like the coupling of test mass jitter into displacement readout, and fluctuations of the laser frequency or optical pathlength difference. Ground testing of pre-flight hardware of the Optical Metrology Subsystem is currently ongoing at the Albert Einstein Institute Hannover. In collaboration with NASA Goddard Space Flight Center, the LPF mission data analysis tool LTPDA is being used to analyze the data product of these tests. Furthermore, the noise subtraction techniques and in-flight experiment runs for noise characterization are being defined as part of the mission experiment master plan. We will present the data analysis outcome of pre-flight hardware ground tests and possible noise subtraction strategies for in-flight instrument operations.

  1. Internal communication: challenges and instruments

    International Nuclear Information System (INIS)

    Stiopol, Mihaela; Rizea, Lavinia

    2007-01-01

    Mike Hughes, the publisher for Publicity Express once said that 'Without Public Relations a terrible thing happens: nothing'. The term 'Public Relations' describes the efficient and coherent organization of external and internal communication. A company has an external public and an internal one as well. The employees of an organization are important carriers of the message the organization wants to transmit, but moreover, they are the driving engine behind the success of an enterprise. Better informed employees are more confident and prepared to get involved in challenging tasks such as obtaining public support for nuclear power. Internal communication is the continuous flux of information on all hierarchic levels both horizontally and vertically. The efficient usage of internal communication tools brings great advantages and benefits for the managers and the personnel of an organization. Despite this, organizing an integrated internal communication strategy is a challenging effort for any PR department. The paper deals with the instruments of internal communication, the obstacles usually encountered and the possibilities to apply an integrated strategy in large companies operating in the nuclear field. (authors)

  2. The Juno Gravity Science Instrument

    Science.gov (United States)

    Asmar, Sami W.; Bolton, Scott J.; Buccino, Dustin R.; Cornish, Timothy P.; Folkner, William M.; Formaro, Roberto; Iess, Luciano; Jongeling, Andre P.; Lewis, Dorothy K.; Mittskus, Anthony P.; Mukai, Ryan; Simone, Lorenzo

    2017-11-01

    The Juno mission's primary science objectives include the investigation of Jupiter interior structure via the determination of its gravitational field. Juno will provide more accurate determination of Jupiter's gravity harmonics that will provide new constraints on interior structure models. Juno will also measure the gravitational response from tides raised on Jupiter by Galilean satellites. This is accomplished by utilizing Gravity Science instrumentation to support measurements of the Doppler shift of the Juno radio signal by NASA's Deep Space Network at two radio frequencies. The Doppler data measure the changes in the spacecraft velocity in the direction to Earth caused by the Jupiter gravity field. Doppler measurements at X-band (˜ 8 GHz) are supported by the spacecraft telecommunications subsystem for command and telemetry and are used for spacecraft navigation as well as Gravity Science. The spacecraft also includes a Ka-band (˜ 32 GHz) translator and amplifier specifically for the Gravity Science investigation contributed by the Italian Space Agency. The use of two radio frequencies allows for improved accuracy by removal of noise due to charged particles along the radio signal path.

  3. Comet coma sample return instrument

    Science.gov (United States)

    Albee, A. L.; Brownlee, Don E.; Burnett, Donald S.; Tsou, Peter; Uesugi, K. T.

    1994-01-01

    The sample collection technology and instrument concept for the Sample of Comet Coma Earth Return Mission (SOCCER) are described. The scientific goals of this Flyby Sample Return are to return to coma dust and volatile samples from a known comet source, which will permit accurate elemental and isotopic measurements for thousands of individual solid particles and volatiles, detailed analysis of the dust structure, morphology, and mineralogy of the intact samples, and identification of the biogenic elements or compounds in the solid and volatile samples. Having these intact samples, morphologic, petrographic, and phase structural features can be determined. Information on dust particle size, shape, and density can be ascertained by analyzing penetration holes and tracks in the capture medium. Time and spatial data of dust capture will provide understanding of the flux dynamics of the coma and the jets. Additional information will include the identification of cosmic ray tracks in the cometary grains, which can provide a particle's process history and perhaps even the age of the comet. The measurements will be made with the same equipment used for studying micrometeorites for decades past; hence, the results can be directly compared without extrapolation or modification. The data will provide a powerful and direct technique for comparing the cometary samples with all known types of meteorites and interplanetary dust. This sample collection system will provide the first sample return from a specifically identified primitive body and will allow, for the first time, a direct method of matching meteoritic materials captured on Earth with known parent bodies.

  4. Instrumentation, Control, and Intelligent Systems

    Energy Technology Data Exchange (ETDEWEB)

    2005-09-01

    Abundant and affordable energy is required for U.S. economic stability and national security. Advanced nuclear power plants offer the best near-term potential to generate abundant, affordable, and sustainable electricity and hydrogen without appreciable generation of greenhouse gases. To that end, Idaho National Laboratory (INL) has been charged with leading the revitalization of nuclear power in the U.S. The INL vision is to become the preeminent nuclear energy laboratory with synergistic, world-class, multi-program capabilities and partnerships by 2015. The vision focuses on four essential destinations: (1) Be the preeminent internationally-recognized nuclear energy research, development, and demonstration laboratory; (2) Be a major center for national security technology development and demonstration; (3) Be a multi-program national laboratory with world-class capabilities; (4) Foster academic, industry, government, and international collaborations to produce the needed investment, programs, and expertise. Crucial to that effort is the inclusion of research in advanced instrumentation, control, and intelligent systems (ICIS) for use in current and advanced power and energy security systems to enable increased performance, reliability, security, and safety. For nuclear energy plants, ICIS will extend the lifetime of power plant systems, increase performance and power output, and ensure reliable operation within the system's safety margin; for national security applications, ICIS will enable increased protection of our nation's critical infrastructure. In general, ICIS will cost-effectively increase performance for all energy security systems.

  5. Instrumentation, Control, and Intelligent Systems

    International Nuclear Information System (INIS)

    Not Available

    2005-01-01

    Abundant and affordable energy is required for U.S. economic stability and national security. Advanced nuclear power plants offer the best near-term potential to generate abundant, affordable, and sustainable electricity and hydrogen without appreciable generation of greenhouse gases. To that end, Idaho National Laboratory (INL) has been charged with leading the revitalization of nuclear power in the U.S. The INL vision is to become the preeminent nuclear energy laboratory with synergistic, world-class, multi-program capabilities and partnerships by 2015. The vision focuses on four essential destinations: (1) Be the preeminent internationally-recognized nuclear energy research, development, and demonstration laboratory; (2) Be a major center for national security technology development and demonstration; (3) Be a multi-program national laboratory with world-class capabilities; (4) Foster academic, industry, government, and international collaborations to produce the needed investment, programs, and expertise. Crucial to that effort is the inclusion of research in advanced instrumentation, control, and intelligent systems (ICIS) for use in current and advanced power and energy security systems to enable increased performance, reliability, security, and safety. For nuclear energy plants, ICIS will extend the lifetime of power plant systems, increase performance and power output, and ensure reliable operation within the system's safety margin; for national security applications, ICIS will enable increased protection of our nation's critical infrastructure. In general, ICIS will cost-effectively increase performance for all energy security systems

  6. European Languages: Instruments and Symbols

    Directory of Open Access Journals (Sweden)

    Martina Ožbot

    2008-07-01

    Further, the role of Latin as the single most important European language over the centuries and as a unifying feature of European culture is discussed. Parallels are drawn between Latin as the historical European lingua franca on the one hand and English as the modern language of international communication on the other: the importance of both languages started growing after substantial territorial expansion of their speakers and it was especially the political and economic power associated to these languages that played a significant role in their diffusion and long-term influence. Taking into consideration the instrumental as well as the symbolic function of languages, the question about the relationship between English and other European languages in today’s Europe is dealt with; it is suggested that the European languages are in principle not endangered as a result of the spread of English, with the exception of those instances in which English has been taking over the functions they have traditionally performed as national or community languages. It is emphasized that the future of Europe lies in the promotion of biand multilingualism, which have, in actual fact, been present on this continent throughout its history, and which in the cases of some European languages (e.g. Catalan, Basque, Irish, etc. have been successfully enhanced over the past decades.

  7. Instrumentation at pulsed neutron sources

    International Nuclear Information System (INIS)

    Carpenter, J.M.; Lander, G.H.; Windsor, C.G.

    1984-01-01

    Scientific investigations involving the use of neutron beams have been centered at reactor sources for the last 35 years. Recently, there has been considerable interest in using the neutrons produced by accelerator driven (pulsed) sources. Such installations are in operation in England, Japan, and the United States. In this article a brief survey is given of how the neutron beams are produced and how they can be optimized for neutron scattering experiments. A detailed description is then given of the various types of instruments that have been, or are planned, at pulsed sources. Numerous examples of the scientific results that are emerging are given. An attempt is made throughout the article to compare the scientific opportunities at pulsed sources with the proven performance of reactor installations, and some familiarity with the latter and the general field of neutron scattering is assumed. New areas are being opened up by pulsed sources, particularly with the intense epithermal neutron beams, which promise to be several orders of magnitude more intense than can be obtained from a thermal reactor

  8. Remote Monitoring of Instrumentation in Sealed Compartments

    International Nuclear Information System (INIS)

    Landron, Clinton; Moser, John C.

    1999-01-01

    The Instrumentation and Telemetry Departments at Sandia National Laboratories have been exploring the instrumentation of sealed canisters where the flight application will not tolerate either the presence of a chemical power source or penetration by power supply wires. This paper will describe the application of a low power micro-controller based instrumentation system that uses magnetic coupling for both power and data to support a flight application

  9. Instruments and accessories for neutron scattering research

    International Nuclear Information System (INIS)

    Ishii, Yoshinobu; Morii, Yukio

    2000-04-01

    This report describes neutron scattering instruments and accessories installed by four neutron scattering research groups at the ASRC (Advanced Science Research Center) of the JAERI and the recent topics of neutron scattering research using these instruments. The specifications of nine instruments (HRPD, BIX-I, TAS-1 and PNO in the reactor hall, RESA, BIX-II, TAS-2, LTAS and SANS-J in the guide hall of the JRR-3M) are summarized in this booklet. (author)

  10. Virtual experiment instrument of nuclear pulse measuring

    International Nuclear Information System (INIS)

    Shan Jian; Zhao Xiuliang; Yu Hong; Zhang Meiqin

    2009-01-01

    Study on the scheme of application of virtual instrument(VI) technique in measuring of nuclear pulse. The system of Counter based on technology of LabVIEW and NI company's products USB-6009-DAQ is developed. Virtual nuclear instrument-Virtual Counter is realized. This system extends the application of technology of virtual instrument. The experimental results indicate that the system of Counter had the good counting measuring function of Nuclear Pulse. (authors)

  11. Report of the Instrumentation Service - Annex C

    International Nuclear Information System (INIS)

    Mikic, N.; Majstorovic, D.

    1993-01-01

    This report describes the tasks and organizational structure of the Instrumentation service. The most important task of this Service is control and maintenance of the reactor control and protection instruments, operation control, and dosimetry system. Besides data about this basic instrumentation, the report includes data about control and maintenance of other electronic equipment, inspection of the reactor vessel and spent fuel storage pool and describes activities related to renewal of the equipment [sr

  12. Report of the Instrumentation Service - Annex C

    International Nuclear Information System (INIS)

    Mikic, N.

    1999-01-01

    This report describes the tasks and organizational structure of the Instrumentation service. The most important task of this Service is control and maintenance of the reactor control and protection instruments, operation control, and dosimetry system. Besides data about this basic instrumentation, the report includes data about control and maintenance of other electronic equipment, inspection of the reactor vessel and spent fuel storage pool and describes activities related control and maintenace of the experimental devices [sr

  13. Report of the Instrumentation Service - Annex C

    International Nuclear Information System (INIS)

    Mikic, N.

    2000-01-01

    This report describes the tasks and organizational structure of the Instrumentation service. The most important task of this Service is control and maintenance of the reactor control and protection instruments, operation control, and dosimetry system. Besides data about this basic instrumentation, the report includes data about control and maintenance of other electronic equipment, inspection of the reactor vessel and spent fuel storage pool and describes activities related control and maintenace of the experimental devices [sr

  14. Nuclear reactor instrumentation at research reactor renewal

    International Nuclear Information System (INIS)

    Baers, B.; Pellionisz, P.

    1981-10-01

    The paper overviews the state-of-the-art of research reactor renewals. As a case study the instrumentation reconstruction of the Finnish 250 kW TRIGA reactor is described, with particular emphasis on the nuclear control instrumentation and equipment which has been developed and manufactured by the Central Research Institute for Physics, Budapest. Beside the presentation of the nuclear instrument family developed primarily for research reactor reconstructions, the quality assurance policy conducted during the manufacturing process is also discussed. (author)

  15. Report of the Instrumentation Service - Annex C

    International Nuclear Information System (INIS)

    Majstorovic, D.

    1986-01-01

    This report describes the tasks and organizational structure of the Instrumentation service. The most important task of this Service is control and maintenance of the reactor control and protection instruments, operation control, and dosimetry system. Besides data about this basic instrumentation, the report includes data about control and maintenance of other electronic equipment, inspection of the reactor vessel and spent fuel storage pool and describes activities related to renewal of the equipment [sr

  16. Report of the Instrumentation Service - Annex C

    International Nuclear Information System (INIS)

    Majstorovic, D.

    1988-01-01

    This report describes the tasks and organizational structure of the Instrumentation service. The most important task of this Service is control and maintenance of the reactor control and protection instruments, operation control, and dosimetry system. Besides data about this basic instrumentation, the report includes data about control and maintenance of other electronic equipment, inspection of the reactor vessel and spent fuel storage pool and describes activities related to renewal of the equipment [sr

  17. Increasing Laser Stability with Improved Electronic Instruments

    Science.gov (United States)

    Troxel, Daylin; Bennett, Aaron; Erickson, Christopher J.; Jones, Tyler; Durfee, Dallin S.

    2010-03-01

    We present several electronic instruments developed to implement an ultra-stable laser lock. These instruments include a high speed, low noise homodyne photo-detector; an ultrahigh stability, low noise current driver with high modulation bandwidth and digital control; a high-speed, low noise PID controller; a low-noise piezo driver; and a laser diode temperature controller. We will present the theory of operation for these instruments, design and construction techniques, and essential characteristics for each device.

  18. Instrument to collect fogwater for chemical analysis

    OpenAIRE

    Jacob, Daniel J.; Waldman, Jed M.; Haghi, Mehrdad; Hoffmann, Michael R.; Flagan, Richard C.

    1985-01-01

    An instrument is presented which collects large samples of ambient fogwater by impaction of droplets on a screen. The collection efficiency of the instrument is determined as a function of droplet size, and it is shown that fog droplets in the range 3–100-µm diameter are efficiently collected. No significant evaporation or condensation occurs at any stage of the collection process. Field testing indicates that samples collected are representative of the ambient fogwater. The instrument may ea...

  19. Seismic instrumentation for nuclear power plants

    International Nuclear Information System (INIS)

    Senne Junior, M.

    1983-07-01

    A seismic instrumentation system used in Nuclear Power Plants to monitor the design parameters of systems, structures and components, needed to provide safety to those plants, against the action of earth quarks is described. The instrumentation is based on the nuclear standards and other components used, as well as their general localization is indicated. The operation of the instrumentation system as a whole and the handling of the recovered data are dealt with accordingly. The accelerometer is described in detail. (Author) [pt

  20. Instrument validation system of general application

    International Nuclear Information System (INIS)

    Filshtein, E.L.

    1990-01-01

    This paper describes the Instrument Validation System (IVS) as a software system which has the capability of evaluating the performance of a set of functionally related instrument channels to identify failed instruments and to quantify instrument drift. Under funding from Combustion Engineering (C-E), the IVS has been developed to the extent that a computer program exists whose use has been demonstrated. The initial development work shows promise for success and for wide application, not only to power plants, but also to industrial manufacturing and process control. Applications in the aerospace and military sector are also likely

  1. Millimeter-wave Instrumentation Test Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Millimeter-wave Instrumentation Test Facility conducts basic research in propagation phenomena, remote sensing, and target signatures. The facility has a breadth...

  2. Seismic instrumentation for nuclear power plants

    International Nuclear Information System (INIS)

    Senne Junior, M.

    1983-01-01

    A seismic instrumentation system used in Nuclear Power Plants to monitor the design parameters of systems, structures and components, needed to provide safety to those Plants, against the action of earthquakes is described. The instrumentation described is based on the nuclear standards in force. The minimum amount of sensors and other components used, as well as their general localization, is indicated. The operation of the instrumentation system as a whole and the handling of the recovered data are dealt with accordingly. The various devices used are not covered in detail, except for the accelerometer, which is the seismic instrumentation basic component. (Author) [pt

  3. LOFT instrumented fuel design and operating experience

    International Nuclear Information System (INIS)

    Russell, M.L.

    1979-01-01

    A summary description of the Loss-of-Fluid Test (LOFT) system instrumented core construction details and operating experience through reactor startup and loss-of-coolant experiment (LOCE) operations performed to date are discussed. The discussion includes details of the test instrumentation attachment to the fuel assembly, the structural response of the fuel modules to the forces generated by a double-ended break of a pressurized water reactor (PWR) coolant pipe at the inlet to the reactor vessel, the durability of the LOFT fuel and test instrumentation, and the plans for incorporation of improved fuel assembly test instrumentation features in the LOFT core

  4. Instrumental methods of analysis, 7th edition

    International Nuclear Information System (INIS)

    Willard, H.H.; Merritt, L.L. Jr.; Dean, J.A.; Settle, F.A. Jr.

    1988-01-01

    The authors have prepared an organized and generally polished product. The book is fashioned to be used as a textbook for an undergraduate instrumental analysis course, a supporting textbook for graduate-level courses, and a general reference work on analytical instrumentation and techniques for professional chemists. Four major areas are emphasized: data collection and processing, spectroscopic instrumentation and methods, liquid and gas chromatographic methods, and electrochemical methods. Analytical instrumentation and methods have been updated, and a thorough citation of pertinent recent literature is included

  5. LESSER KNOWN MUSICAL INSTRUMENTS IN KOSOVO

    Directory of Open Access Journals (Sweden)

    Rešad Fazli

    2012-04-01

    Full Text Available In this paper the author presented the instruments that were originated in this region, as well as those instruments that are brought from other regions, and became deeply carved into the tradition and culture of the local people, that they feel as their own. Some of these instruments are kept only here in this region, and they are not used anymore in the area they originated from. This paper also covers instruments that are rarely used or completely lost in this region.

  6. Design requirements for the SWIFT instrument

    International Nuclear Information System (INIS)

    Rahnama, P; McDade, I; Shepherd, G; Gault, W

    2013-01-01

    The Stratospheric Wind Interferometer for Transport studies (SWIFT) instrument is a proposed limb-viewing satellite instrument that employs the method of Doppler Michelson interferometry to measure stratospheric wind velocities and ozone densities in the altitude range of 15–45 km. The values of the main instrument parameters including filter system parameters and Michelson interferometer parameters are derived using simulations and analyses. The system design requirements for the instrument and spacecraft are presented and discussed. Some of the retrieval-imposed design requirements are also discussed. Critical design issues are identified. The design optimization process is described. The sensitivity of wind measurements to instrument characteristics is investigated including the impact on critical design issues. Using sensitivity analyses, the instrument parameters were iteratively optimized in order to meet the science objectives. It is shown that wind measurements are sensitive to the thermal sensitivity of the instrument components, especially the narrow filter and the Michelson interferometer. The optimized values of the main system parameters including Michelson interferometer optical path difference, instrument visibility, instrument responsivity and knowledge of spacecraft velocity are reported. This work also shows that the filter thermal drift and the Michelson thermal drift are two main technical risks. (paper)

  7. Rotary mode system initial instrument calibration

    International Nuclear Information System (INIS)

    Johns, B.R.

    1994-01-01

    The attached report contains the vendor calibration procedures used for the initial instrument calibration of the rotary core sampling equipment. The procedures are from approved vendor information files

  8. The Sensors and Instrumentation Knowledge Transfer Network

    International Nuclear Information System (INIS)

    Cooper, P

    2009-01-01

    The Sensors and Instrumentation KTN has established itself as the UK's national network in sensors and instrumentation, developing a community of over 2,250 member organisations. This paper describes the background to Knowledge Transfer Networks (KTNs) and the changes that are happening to KTNs at a national level, before describing the market size, activities and successes of the Sensors and Instrumentation KTN. The paper concludes by describing the merger between the Sensors and Instrumentation KTN and four other KTNs to create a new KTN, with a working title of the Electronics, Sensors and Photonics KTN.

  9. [What's new in instrumental dermatology?].

    Science.gov (United States)

    Amici, J-M

    2014-12-01

    This "What's new in instrumental dermatology" focuses on cutaneous oncologic surgery, base on a review of the 2012-2014 literature. First, the ability of dermatologists to make a good "oncologic reading of tumors" is the key of radical surgical treatment. Advantages and disadvantages of the biopsy are discussed. Then, the second message is the management of anticoagulants, that should not be interrupted for skin surgery. Despite recommendations, this practice is not followed in 40% of cases; this point is critical because bleeding complications are minor compared to potential morbidity of thrombotic events when stopping these medications. Regarding infection, nasal carriage of Staphylococcus aureus is identified as a risk factor for wound infection. A preoperative shower with chlorhexidine and mupirocin topical decolonization of nostril reduces this risk. Surgical techniques are trying to reach minimalism, by reducing undermining and scarring. On the trunk, using deep slow resorbable sutures improve scarring. In addition using adhesive sutures (strip) reduce the wideness of scar. On the face, the lower third of the nose is the most challenging because of the free edges, which are deformable. In this location bilobed or trilobed transposition flap offer the advantage of remaining in the nasal aesthetic unit and not disturbing the free edges of the nasal orifices. Regarding scarring, early hypertrophic scar is now well defined and linked with transposition flaps of the nasal region. An early treatment with intralesional corticosteroid injection appears to be effective. Finally, the biological mechanism of the effectiveness of compression in the prevention and treatment of dystrophic scar is now clear. The mechanotransduction explain how a mechanical stress of the skin activates biological cell pathways, which regulate the quality of collagen synthesis and the arrangement of skin fibrosis. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  10. Developing the TRYAD Science Instrument

    Science.gov (United States)

    Van Eck, K. T.; Jenke, P.; Briggs, M. S.; Fuchs, J.; Capps, L.

    2017-12-01

    Terrestrial gamma-ray flashes (TGFs) are brief MeV gamma-ray flashes that are associated with thunderstorms, around 12km in altitude, and are viewed by orbiting satellites. These bright flashes of high energy photons were discovered in 1994. The two major models for TGFs that originate in thunderstorms are the Lightning Leader and Relativistic Feedback Discharge (RFD) model. Both depend on energetic electrons radiating via bremsstrahlung emission. The Lightning Leader model theorizes that lightning step leaders can accelerate electrons to relativistic speeds. The RFD model states that an energetic seed particle can be accelerated to relativistic speeds by strong electric fields inside of a thunderstorm. The main difference in the results of the two models is as follows; the Lightning Leader model results in a wider beam of gamma-rays than the RFD model because the electric field of a thunderstorm is more structured than that of lightning. The TRYAD mission will be the first to fly two detectors, inside CubeSats, in formation to detect TGFs from multiple points in the sky. The data from the CubeSats and the World Wide Lightning Location Network (WWLLN) will likely provide enough insight to constrain or eliminate some of the existing models for TGFs.This summer was spent testing components and constructing the engineering model of the scientific instrument that will be used to detect TGFs. The detector is made up of four lead-doped plastic scintillators which are coupled to arrays of Silicon Photomultipliers (SiPM). The signal from the SiPM array is then fed into a discriminator where a lower energy estimate can be determined and photon counts are recorded. I will present the progress made over the summer constructing the engineering model.

  11. Combining within and between instrument information to estimate precision

    International Nuclear Information System (INIS)

    Jost, J.W.; Devary, J.L.; Ward, J.E.

    1980-01-01

    When two instruments, both having replicated measurements, are used to measure the same set of items, between instrument information may be used to augment the within instrument precision estimate. A method is presented which combines the within and between instrument information to obtain an unbiased and minimum variance estimate of instrument precision. The method does not assume the instruments have equal precision

  12. Vision though afocal instruments: generalized magnification and eye-instrument interaction

    Science.gov (United States)

    Harris, William F.; Evans, Tanya

    2018-04-01

    In Gaussian optics all observers experience the same magnification, the instrument's angular magnification, when viewing distant objects though a telescope or other afocal instruments. However, analysis in linear optics shows that this is not necessarily so in the presence of astigmatism. Because astigmatism may distort and rotate images it is appropriate to work with generalized angular magnification represented by a 2 × 2 matrix. An expression is derived for the generalized magnification for an arbitrary eye looking through an arbitrary afocal instrument. With afocal instruments containing astigmatic refracting elements not all eyes experience the same generalized magnification; there is interaction between eye and instrument. Eye-instrument interaction may change as the instrument is rotated about its longitudinal axis, there being no interaction in particular orientations. A simple numerical example is given. For sake of completeness, expressions for generalized magnification are also presented in the case of instruments that are not afocal and objects that are not distant.

  13. Void Fraction Instrument operation and maintenance manual

    International Nuclear Information System (INIS)

    Borgonovi, G.; Stokes, T.I.; Pearce, K.L.; Martin, J.D.; Gimera, M.; Graves, D.B.

    1994-09-01

    This Operations and Maintenance Manual (O ampersand MM) addresses riser installation, equipment and personnel hazards, operating instructions, calibration, maintenance, removal, and other pertinent information necessary to safely operate and store the Void Fraction Instrument. Final decontamination and decommissioning of the Void Fraction Instrument are not covered in this document

  14. Fabrication of internally instrumented reactor fuel rods

    International Nuclear Information System (INIS)

    Schmutz, J.D.; Meservey, R.H.

    1975-01-01

    Procedures are outlined for fabricating internally instrumented reactor fuel rods while maintaining the original quality assurance level of the rods. Instrumented fuel rods described contain fuel centerline thermocouples, ultrasonic thermometers, and pressure tubes for internal rod gas pressure measurements. Descriptions of the thermocouples and ultrasonic thermometers are also contained

  15. Patient perspective: choosing or developing instruments.

    Science.gov (United States)

    Kirwan, John R; Fries, James F; Hewlett, Sarah; Osborne, Richard H

    2011-08-01

    Previous Outcome Measures in Rheumatology (OMERACT) meetings recognized that patients view outcomes of intervention from a different perspective. This preconference position paper briefly sets out 2 patient-reported outcome (PRO) instrument approaches, the PROMISE computer adaptive testing (CAT) system and development of a rheumatoid arthritis-specific questionnaire to measure fatigue; a tentative proposal for a PRO instrument development pathway is also made.

  16. DARE: a dedicated aerosols retrieval instrument

    NARCIS (Netherlands)

    Court, A.J.; Smorenburg, K.; Courrèges-Lacoste, G.B.; Visser, H.; Leeuw, G. de; Decae, R.

    2004-01-01

    Satellite remote sensing of aerosols is a largely unresolved problem. A dedicated instrument aimed at aerosols would be able to reduce the large uncertainties connected to this kind of remote sensing. TNO is performing a study of a space based instrument for aerosol measurements, together with the

  17. Conceptual design of safety instrumentation for PFBR

    International Nuclear Information System (INIS)

    Muralikrishna, G.; Seshadri, U.; Raghavan, K.

    1996-01-01

    Instrumentation systems enable monitoring of the process which in turn enables control and shutdown of the process as per the requirements. Safety Instrumentation due to its vital importance has a stringent role and this needs to be designed methodically. This paper presents the details of the conceptual design for PFBR. (author). 4 figs, 3 tabs

  18. IAEA programme on maintenance of nuclear instruments

    International Nuclear Information System (INIS)

    Vuister, P.H.

    1986-01-01

    The Medical Applications Section in the Division of Life Sciences of the International Atomic Energy Agency has been engaged since 1975 in activities aimed at the more effective use of nuclear instruments. Activities and achievements are described concerning the conditioning of laboratories, preventive maintenance and repair of instruments, the management thereof, space parts and the promotion of local training in these subjects. (author)

  19. Technology evolution of the Tropomi instrument

    NARCIS (Netherlands)

    Vries, J. de; Hoogeveen, R.; Voors, R.; Kleipool, Q.; Veefkind, P.; Aben, I.; Snel, R.; Valk, N.C.J. van der; Visser, H.; Otter, G.C.J.

    2012-01-01

    TROPOMI is the sun backscatter trace gas instrument on ESA's Sentinel-5 precursor satellite. TROPOMI builds upon a rich heritage from similar instruments, the main ones being SCIAMACHY on ESA's ENVISAT and OMI on NASA's AURA satellite. This paper explains how the technology from the heritage

  20. Specialized instrument for radiation assistance teams

    International Nuclear Information System (INIS)

    Applegate, J.A.

    1985-08-01

    A specialized multiradiation instrument for radiation assistance teams (RAT's) has been designed; a working prototype has been constructed and field tested. The instrument detects alpha, beta, and gamma radiation simultaneously with simple red, yellow, and green meter indications and audio outputs. It is basically intended for DOE radiation assistance teams but would have application to any government, military, or industrial radiation accident team