Sample records for grisham cheryl wozniak

  1. 78 FR 6173 - Diana Del Grosso, Ray Smith, Joseph Hatch, Cheryl Hatch, Kathleen Kelley, Andrew Wilklund, and... (United States)


    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF TRANSPORTATION Surface Transportation Board Diana Del Grosso, Ray Smith, Joseph Hatch, Cheryl Hatch, Kathleen... Smith, Joseph Hatch, Cheryl Hatch, Kathleen Kelley, Andrew Wilklund, and Richard Kosiba...

  2. Mida andis teile Tallinna ülikooli suvekoolis osalemine? / Ipios Nikos, Cheryl Johnson, Jevgenijs Kaktinš...[jt.

    Index Scriptorium Estoniae


    Küsimusele vastasid arst Ipios Nikos, luteri-anglikaani vaimulik, arheoloog Cheryl Johnson, ökonomist Jevgenijs Kaktinš, filosoofia magistrant Gabriele Avincola ja filosoofia üliõpilane Kaia Otstak

  3. Mida andis teile Tallinna ülikooli suvekoolis osalemine? / Ipios Nikos, Cheryl Johnson, Jevgenijs Kaktinš...[jt.

    Index Scriptorium Estoniae


    Küsimusele vastasid arst Ipios Nikos, luteri-anglikaani vaimulik, arheoloog Cheryl Johnson, ökonomist Jevgenijs Kaktinš, filosoofia magistrant Gabriele Avincola ja filosoofia üliõpilane Kaia Otstak

  4. Whiteness as Cursed Property: An Interdisciplinary Intervention with Joyce Carol Oates’s Bellefleur and Cheryl Harris’s “Whiteness as Property”

    Directory of Open Access Journals (Sweden)

    Karen Gaffney


    Full Text Available This article begins with the assertion that now more than ever, in the aftermath of Ferguson and in a time when many believe our society to be post-racial, we need to bring together scholars and activists who care about racial justice, regardless of discipline, and build interdisciplinary tools for fighting racism. Furthermore, we need to understand and reveal how whiteness has been socially constructed because the power of whiteness lies in its invisibility, and that fuels the perpetuation of systemic racism. In making whiteness visible, we can see how it has been wielded as a weapon, which in turn will allow us to see how destructive it is for everyone, whites included. As part of this work, we need to break down the disciplinary boundary between literary studies and critical race theory (a field within legal studies that examines systemic racism in the context of the law. One example of such an interdisciplinary intervention is to bring together Cheryl Harris, a critical race theorist, and Joyce Carol Oates, a novelist. Harris published one of the foundational pieces of critical race theory in 1993 with her law review article “Whiteness as Property,” a legal analysis of whiteness, and Oates produced a masterpiece of American literature in 1980 with her novel Bellefleur, a complex story of a powerful white family that spans seven generations. This pairing lays the groundwork for the type of interdisciplinary dialogue we need because, within literary studies, when the novelist is white and the characters are white, there is still very little emphasis on the study of whiteness even though race is a significant focus of attention when the novelist and characters are people of color. Whiteness is still invisible, and that is part of the problem I am describing, both within literary studies and in our society at large. We need an interdisciplinary intervention to pull back the curtain on whiteness, see how it operates, recognize its danger, and

  5. Narrative Inqui ry and Its Appl ication in Teacher knowledge Research---A Dialogue with Prof.Cheryl Craig from University of Houston%叙事探究及其在教师知识研究中的运用--与美国休斯敦大学谢丽尔·克雷格教授对话

    Institute of Scientific and Technical Information of China (English)

    魏戈; 陈向明


    美国休斯敦大学谢丽尔·克雷格教授是当代国际教育叙事研究的领军人物,并在教师知识研究领域做出了有益的探索。在本次访谈中,克雷格教授结合自己在美国南部伊格中学长达数十年的扎根研究,针对叙事探究的哲学与方法论基础、叙事探究在教师知识研究中的实际运用以及该研究方法的发展前景等问题做了详细介绍,为我们在教师教育领域开展叙事探究提供了有力的借鉴。%Cheryl Craig is the current international pioneer of narrative inquiry, and has made many intellectual contributions to teacher knowledge research field.In this interview, based on her decades of field study experience in Yeager Middle School in southern USA, Cheryl Craig introduces the theoretical foundations, appl ication and prospective development of narrative inquiry in teacher knowledge research, which could be a powerful support for us to use narrative inquiry as an approach in teacher education.

  6. Poola pole Ignalina plaane lukku löönud / Piotr Wozniak ; interv. Raimo Poom

    Index Scriptorium Estoniae

    Wozniak, Piotr


    Äsja laialisaadetud Poola valitsuse majandusministri sõnul soovib Poola olla Ignalina tuumaelektrijaama projektis aktiivne investor, st Poola soovib teatud osa selle kavandatavast võimsusest, minimaalselt 1000 MW. Meelis Atonen, Villu Reiljan ja Evelyn Sepp vastavad küsimusele, kas Ignalina suudab põlevkivienergiat asendada

  7. Regstellende aksie : die omvang en implementering daarvan in die werkplek / Rene Hilary Cheryl-Anne Koraan



    The rationale behind affirmative action is the endeavour to address the inequalities and injustices created by discrimination in the past. Affirmative action was implemented in 1994 via the Constitution of the Republic of South Africa, 1996. Section 9(2) of the Constitution is known as the affirmative action clause. The United States of America was one of the first countries to implement affirmative action. The Constitution provides that all people have the right to equality. The legislatu...

  8. 78 FR 42064 - Before Commissioners: Jon Wellinghoff, Chairman; Philip D. Moeller, John R. Norris, Cheryl A... (United States)


    ... outside expertise to support planning for physical and cyber security, and even to support and improve day... infrastructure members the opportunity to react in a meaningful manner'' to disturbance or other event... events ``to those that give third parties the opportunity to act to mitigate the impact of the event...

  9. 77 FR 69929 - Western Carolina Railway Service Corporation, Steven C. Hawkins and Cheryl R. Hawkins-Continuance... (United States)


    .... Hawkins--Continuance in Control Exemption--Aiken Railway Company, LLC Western Carolina Railway Service... noncarrier Aiken Railway Company, LLC (AIKR), upon AIKR's becoming a Class III rail carrier. This transaction... near Oakwood, S.C.; and (2) the AB Line extending 6.45 miles between milepost AB 23.75 at or near Aiken...

  10. 76 FR 72197 - Before Commissioners: Jon Wellinghoff, Chairman; Philip D. Moeller, John R. Norris, and Cheryl A... (United States)


    ...'s requirements. \\16\\ 76 FR 7557 (2011). 11. MISO and NYISO state that Reliability Standard FAC-013-2...) reserved transmission services.\\30\\ Thus, the TPL Reliability Standards do not require a planning... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY...

  11. A Comparison of Power Perceptions Held by Female Nurse and Female Business Executives (United States)


    differences in power perceptions among nurses which included nurse executives ( Heineken & Wozniak, 1988). Sutton and Moore (1985) studied executives...recounts studies involving power related to the nursing profession. The Heineken and Wozniak study specifically addresses perceptions of power held by nurses...less complex; therefore, perceptions of powerlessness was not an issue. Heineken and Wozniak (1988) utilized the Cavanaugh Power 317 Orientation Scale

  12. 75 FR 54695 - Advisory Council on Transportation Statistics; Notice of Meeting (United States)


    ... must notify Tonya Tinsley-Grisham at , not later than September 27, 2010. Members... Statistics, Attention: Tonya Tinsley-Grisham, 1200 New Jersey Avenue, SE., Room E34-403, Washington, DC 20590, or faxed to (202) 366-3640. BTS requests that written comments be received by...

  13. Essentials of nursing research: methods, appraisal, and utilization Denise F Polit Essentials of nursing research: methods, appraisal, and utilization , Cheryl Tatano Beck Lipincott Williams and Wilkins 554 £24.95 0781749727 0781749727 [Formula: see text]. (United States)


    Perhaps not obvious from the title, this book is designed to guide the reader through the process of finding, reading, and critically evaluating published nursing research, and to consider the practical use to which research findings may be put. The reader is led systematically through the stages of finding published studies (with reference to widely available databases), reviewing them in relation to their ethical implications and theoretical bases, scrutinising their design, sampling, data collection and analysis methods, and evaluating the quality of the data generated. Guidelines for producing a written critique of published studies are provided. The book ends with a focus on using research evidence, referring to key models for evidence-based nursing practice. While barriers to research utilisation are discussed, a greater emphasis on this topic might have been expected, given the inclusion of research utilisation within the book's title.

  14. "Faces, Voices & Dreams: A Celebration of the Centennial of the Sheldon Jackson Museum, 1888-1988," Edited by Peter L. Corey. "The Raven's Tail," by Cheryl Samuel. Book Reviews. (United States)

    Jonaitis, Aldona


    Reviews: a volume of 11 essays on the history of Sheldon Jackson Museum and its Eskimo, Aleut, Athabaskan, Tlingit, and Haida collections; and a book analyzing the geometric design, technique, and imagery of 15 "raven's tail robes," early Northwest Coast textiles predating the more familiar Chilkat blankets. (SV)

  15. Väljaspool iseennast / Aita Kivi

    Index Scriptorium Estoniae

    Kivi, Aita, 1954-


    Sisu : Jaan Kaplinski. Silm. Hektor; John Grisham. Aguliadvokaat; Kerttu Rakke. Kalevipoeg; luulekogu "Armastuse valgus", koost. Peep Ilmet; James Woodall. John Lennon ja Yoko Ono; Donald Braider. El Greco eraelu; Åke Edwardson. Tants ingliga

  16. Väljaspool iseennast / Aita Kivi

    Index Scriptorium Estoniae

    Kivi, Aita, 1954-


    Sisu : Jaan Kaplinski. Silm. Hektor; John Grisham. Aguliadvokaat; Kerttu Rakke. Kalevipoeg; luulekogu "Armastuse valgus", koost. Peep Ilmet; James Woodall. John Lennon ja Yoko Ono; Donald Braider. El Greco eraelu; Åke Edwardson. Tants ingliga

  17. The universal machine from the dawn of computing to digital consciousness

    CERN Document Server

    Watson, Ian


    In less than a human lifetime, computers are transforming economies and societies like no other human invention. This book looks past technology to introduce comuputing pioneers: Babbage, Turing, Wozniak and Jobs, Bill Gates, Tim Berners-Lee, Mark Zuckerberg.

  18. Marco Calamari, Lampi di Cassandra: l’altro Steve

    Directory of Open Access Journals (Sweden)

    Maria Chiara Pievatolo


    Full Text Available L’articolo, pubblicato oggi su “Punto informatico”, è apparentemente dedicato alla differenza fra i due fondatori della Apple: lo Steve Jobs di cui parlano tutti, e l’altro, Wozniak, che ha lasciato l’azienda nel 1985, dopo aver creato i primi due veri personal computer, Apple I e Apple II. Mentre a Wozniak si devono i pochissimi momenti [...

  19. PDA Use by Clinicians has a Positive Impact on Clinical Decision Making. A review of: Dee, Cheryl R., Marilyn Teolis, and Andrew D. Todd. “Physicians’ use of the personal digital assistant (PDA in clinical decision making.” Journal of the Medical Library Association 93.4 (October 2005: 480-6.

    Directory of Open Access Journals (Sweden)

    Suzanne P. Lewis


    Full Text Available Objective – To examine how frequently attending physicians and physicians in training (medical students, interns and residents used PDAs for patient care and to explore physicians’ perceptions of the impact of PDA use on several aspects of clinical care. Design – User study via a questionnaire. Setting – Teaching hospitals in Tennessee, Florida, Alabama, Kentucky, and Pennsylvania in the United States. Subjects – A convenience sample of fifty nine attending physicians and forty-nine physicians in training (108 total, spread unevenly across the five states. Methods – Subjects were recruited by librarians at teaching hospitals to answer a questionnaire which was distributed and collected at medical meetings, as well as by email, mail, and fax. The subjects were required to have and use a PDA, but prior training on PDA use was not a requirement, nor was it offered to the subjects before the study. Most of the questions required the respondent to choose from five Likert scale answers regarding frequency of PDA use: almost always, often, a few times, rarely, or never. In the reporting of results, the options ‘almost always’ and ‘often’ were combined and reported as ‘frequent’, and the options ‘a few times’ and ‘rarely’, were combined and reported as ‘occasional’. Subjects could also record comments for each question, but only for affirmative responses. Subjects were asked about their frequency of PDA use before, during, or after a patient encounter. They were also asked if PDA use had influenced one or more of five aspects of clinical care – decision making, diagnosis, treatment, test ordering, and in-patient hospital length of stay. Data analysis included chi square tests to assess differences between attending physicians and physicians in training regarding frequency of PDA use and the influence of PDA use on the five aspects of clinical care. The subject population was also divided into frequent and occasional users of PDAs, and chi square testing was used to assess differences between these two groups regarding the influence of PDA use on clinical care. A significance value of PMain results – Ninety‐four (87% of the 108 respondents used PDAs for patient encounters. Of this group, 59 were frequent users and 35 were occasional users. There were no significant differences between attending physicians and physicians in training with regard to frequency of PDA use in patient encounters. Sixty-seven percent of the 108 respondents reported that using a PDA had influenced their clinical decision making; over 50% reported that PDA use had influenced changes in patient treatment; 16% reported that PDA use had helped avoid unnecessary tests; 10% reported that PDA use had helped change a patient’s diagnosis; and 6% reported that PDA use had helped shorten a patient’s length of stay. Within these results, there were no statistically significant differences between the attending physicians and the physicians in training. More than 85% of the frequent PDA users (n=59, and 60% of the occasional PDA users (n=35, reported that PDA use had influenced their clinical decision making. The difference between these two groups was statistically significant (PConclusion – PDA use has a positive impact on clinical decision making and patient care. Frequency of PDA use appears to be a factor in determining the perceived impact of PDAs on clinical decision making. However, even those physicians who used PDAs only occasionally reported a positive impact of PDA use on clinical decision making. The status of physicians (attending or in training does not appear to be a determining factor in the frequency of PDA use for patient encounters. Health sciences librarians are well positioned to provide resources and training for PDA use by clinicians.

  20. 76 FR 5814 - Office of the Assistant Secretary for Financial Resources, Office of Grants and Acquisition... (United States)


    ... HUMAN SERVICES Office of the Assistant Secretary for Financial Resources, Office of Grants and... be directed to Cheryl Howe in the HHS/Office of the Secretary, Assistant Secretary for Financial...-5552 or . Dated: January 27, 2011. Debbie H. Ridgely, Acting Deputy Assistant...

  1. Navigating through Social Norms, Negotiating Place: How "American Born Chinese" Motivates Struggling Learners (United States)

    Gomes, Cheryl


    The authors, a ninth-grade teacher in a Special Education English class (Cheryl) and a teacher educator (Bucky), know of each other's work through a mutual interest in graphic novels. This article describes what happened in Cheryl's class when her students read "American Born Chinese" and discussed that text in a blog with its author, Gene Luen…

  2. Rose's Life Lessons: Signed and Spoken (United States)

    McAuliffe, Chris


    In this article, the author shares the experiences of his wife, Cheryl, and his 5-year-old daughter, Rose, when they visited their local high school's child development class. Cheryl and Rose met with over a 100 teenagers teenagers in eight different classes to talk about their family, raising a child with Down syndrome, and their experiences with…

  3. Alatust ülevani / Aita Kivi

    Index Scriptorium Estoniae

    Kivi, Aita, 1954-


    Sisu : Ayn Rand. Allikas ; John Updike. Gertrud ja Glaudius ; Lion Feuchtwanger. Jefta ja tema tütar ; Erich Maria Remarque. Jaam silmapiiril ; Philippe Djian. Betty Blue ; Paul Reiser. Kahekesi ; John Grisham. Firma; Dean Koontz. Hirmu pale ; Armastuskirjad / koost. Jill Dawson ; Roald Dahl. James ja hiigelvirsik ; Spencer Johnson. Jah või ei

  4. An Evaluation of Text-to-Speech Synthesizers in the Foreign Language Classroom: Learners' Perceptions (United States)

    Bione, Tiago; Grimshaw, Jennica; Cardoso, Walcir


    As stated in Cardoso, Smith, and Garcia Fuentes (2015), second language researchers and practitioners have explored the pedagogical capabilities of Text-To-Speech synthesizers (TTS) for their potential to enhance the acquisition of writing (e.g. Kirstein, 2006), vocabulary and reading (e.g. Proctor, Dalton, & Grisham, 2007), and pronunciation…

  5. Evaluating Text-to-Speech Synthesizers (United States)

    Cardoso, Walcir; Smith, George; Fuentes, Cesar Garcia


    Text-To-Speech (TTS) synthesizers have piqued the interest of researchers for their potential to enhance the L2 acquisition of writing (Kirstein, 2006), vocabulary and reading (Proctor, Dalton, & Grisham, 2007) and pronunciation (Cardoso, Collins, & White, 2012; Soler-Urzua, 2011). Despite their proven effectiveness, there is a need for…

  6. 2008. aasta menukaimad / Udo Uibo

    Index Scriptorium Estoniae

    Uibo, Udo, 1956-


    2008. aasta raamatumüügi tulemustest, mulluste menukamate kirjanike nimestikust, mis põhineb USA, Suurbritannia, Prantsusmaa, Saksamaa, Itaalia, Hollandi, Hiina, Hispaania ja Rootsi igakuistel ilukirjanduslike bestsellerite edetabelitel. Esikümnesse kuuluvad: Khaled Hossein, Stieg Larsson, Ken Follett, Stephenie Meyer, Muriel Barbery, Carlos Ruiz Zafón, Anna Gavalda, John Grisham, J. K. Rowling, Henning Mankell

  7. Alatust ülevani / Aita Kivi

    Index Scriptorium Estoniae

    Kivi, Aita, 1954-


    Sisu : Ayn Rand. Allikas ; John Updike. Gertrud ja Glaudius ; Lion Feuchtwanger. Jefta ja tema tütar ; Erich Maria Remarque. Jaam silmapiiril ; Philippe Djian. Betty Blue ; Paul Reiser. Kahekesi ; John Grisham. Firma; Dean Koontz. Hirmu pale ; Armastuskirjad / koost. Jill Dawson ; Roald Dahl. James ja hiigelvirsik ; Spencer Johnson. Jah või ei

  8. Patterns of Change in User-Generated Social Media Behavior among Service Members Who Die by Suicide (United States)


    Brown , Beck, Steer, & Grisham, 2000), but the notion of the warning sign implies short-term or imminent risk, on the order of hours to days or weeks...25/2009 buzzin on chianti wine, what to do next… 14 12/26/2009 has to be up early for the pats game tomorrow, dad doesnt wanna miss the tailgate

  9. 2008. aasta menukaimad / Udo Uibo

    Index Scriptorium Estoniae

    Uibo, Udo, 1956-


    2008. aasta raamatumüügi tulemustest, mulluste menukamate kirjanike nimestikust, mis põhineb USA, Suurbritannia, Prantsusmaa, Saksamaa, Itaalia, Hollandi, Hiina, Hispaania ja Rootsi igakuistel ilukirjanduslike bestsellerite edetabelitel. Esikümnesse kuuluvad: Khaled Hossein, Stieg Larsson, Ken Follett, Stephenie Meyer, Muriel Barbery, Carlos Ruiz Zafón, Anna Gavalda, John Grisham, J. K. Rowling, Henning Mankell

  10. Quantitative Tractography and Volumetric MRI in Blast and Blunt Force TBI: Predictors of Neurocognitive and Behavioral Outcome (United States)


    aneurysm ) of individuals with chronic symptoms of fatigue follow- ing brain injury (mean = 44 months since injury), the FIS provided the most...582. 61. Wozniak JR, Krach L, Ward E, et al. Neurocognitive and neu- roimaging correlates of pediatric traumatic brain injury: a diffusion tensor

  11. What Students Can Learn from Steve Jobs. Footnotes. Volume 16, Number 08 (United States)

    Husick, Lawrence


    A few days ago, Steve Jobs, the rockstar founder and Chief Executive Officer of Apple, Inc. resigned from his job to become Chairman of the Board, instead. For more than ten years, Mr. Jobs has been paid one dollar a year to run what has become the most valuable company in the world. From his first partner, Steve Wozniak, to the small team of…

  12. Leaders in Computing Changing the digital world

    CERN Document Server

    IT, BCS -The Chartered Institute for; Booch, Grady; Torvalds, Linus; Wozniak, Steve; Cerf, Vint; Spärck Jones, Karen; Berners-Lee, Tim; Wales, Jimmy; Shirley, Stephanie


    This collection of interviews provides a fascinating insight into the thoughts and ideas of influential figures from the world of IT and computing, such as Sir Tim Berners-Lee, Donald Knuth, Linus Torvalds, Jimmy Wales and Steve Wozniak. It gives an excellent overview of important developments in this diverse field over recent years.

  13. Neuro-Immune Mechanisms in Response to Venezuelan Equine Encephalitis Virus Infection (United States)


    parents, Hank and Gail Schoneboom. They instilled in me a work ethic to be successful in any rigorous endeavor and nurtured the curiosity of the child...are the resident macrophages of the CNS, thought to arise from a common embryologic origin, the mesoderm (Cuadros and Navascues, 1998, Wozniak, 1998

  14. Living on the Future Edge: Windows on Tomorrow (United States)

    Jukes, Ian; McCain, Ted; Crockett, Lee


    "Living on the Future Edge" challenges school leaders to rethink longstanding paradigms and transform pedagogy for tomorrow's learners. Apple Computer, Inc. co-founder Steve Wozniak's foreword underscores the overwhelming need to adjust traditional instruction to fit today's high-tech world. The book explores this new landscape and…

  15. 78 FR 803 - Revisions to Electric Reliability Organization Definition of Bulk Electric System and Rules of... (United States)


    ...; Philip D. Moeller, John R. Norris, and Cheryl A. LaFleur. FINAL RULE (Issued December 20, 2012) Table of...\\ Holland Comments at 2. 35. Some commenters oppose approval on various grounds. For example, NARUC is...

  16. A New Edition of an Old Favorite

    Directory of Open Access Journals (Sweden)

    S. Krishna Sundari


    Full Text Available Review of: Molecular Biotechnology—Principles and Applications of Recombinant DNA , 4th ed.; Bernard R. Glick, Jack J. Pasternak, Cheryl L. Patten; (2010 . ASM Press, Washington, DC. 1000 pages.

  17. Neuropsychological and neurophysiological insights into hoarding disorder



    Jessica R Grisham, Peter A Baldwin School of Psychology, University of New South Wales, Sydney, Australia Abstract: Hoarding disorder (HD) is associated with significant personal impairment in function and constitutes a severe public health burden. Individuals who hoard experience intense distress in discarding a large number of objects, which results in extreme clutter. Research and theory suggest that hoarding may be associated with specific deficits in information processing, pa...

  18. Alcohol consumption and the risk of renal cancers in the European Prospective Investigation into Cancer and Nutrition (EPIC). Wozniak MB, Brennan P, Brenner DR, Overvad K, Olsen A, Tjønneland A, Boutron-Ruault MC, Clavel-Chapelon F, Fagherazzi G, Katzke V, Kühn T, Boeing H, Bergmann MM, Steffen A, Naska A, Trichopoulou A, Trichopoulos D, Saieva C, Grioni S, Panico S, Tumino R, Vineis P, Bueno-de-Mesquita HB, Peeters PH, Hjartåker A, Weiderpass E, Arriola L, Molina-Montes E, Duell EJ, Santiuste C, Alonso de la Torre R, Barricarte Gurrea A, Stocks T, Johansson M, Ljungberg B, Wareham N, Khaw KT, Travis RC, Cross AJ, Murphy N, Riboli E, Scelo G.Int J Cancer. 2015 Oct 15;137(8):1953-66. [Epub 2015 Apr 28]. doi: 10.1002/ijc.29559. (United States)

    Jay, Raman; Brennan, P; Brenner; Overvad, K; Olsen, A; Tjønneland, A; Boutron-Ruault, M C; Clavel-Chapelon, F; Fagherazzi; Katzke, V; Kühn, T; Boeing, H; Bergmann, M M; Steffen, A; Naska, A; Trichopoulou, A; Trichopoulos, D; Saieva, C; Grioni, S; Panico, S; Tumino, R; Vineis, P; Bueno-de-Mesquita, H B; Peeters, P H; Hjartåker, A; Weiderpass, E; Arriola, L; Molina-Montes, E; Duell, E J; Santiuste, C; Alonso de la Torre, R; Barricarte Gurrea, A; Stocks, T; Johansson, M; Ljungberg, B; Wareham, N; Khaw, K T; Travis, R C; Cross, A J; Murphy, N; Riboli, E; Scelo, G


    Epidemiologic studies have reported that moderate alcohol consumption is inversely associated with the risk of renal cancer. However, there is no information available on the associations in renal cancer subsites. From 1992 to 2010, 477,325 men and women in the European Prospective Investigation into Cancer and Nutrition cohort were followed for incident renal cancers (n = 931). Baseline and lifetime alcohol consumption was assessed by country-specific, validated dietary questionnaires. Information on past alcohol consumption was collected by lifestyle questionnaires. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated from Cox proportional hazard models. In multivariate analysis, total alcohol consumption at baseline was inversely associated with renal cancer; the HR and 95% CI for the increasing categories of total alcohol consumption at recruitment vs. the light drinkers category were 0.78 (0.62-0.99), 0.82 (0.64-1.04), 0.70 (0.55-0.90), and 0.91 (0.63-1.30), respectively, (ptrend = 0.001). A similar relationship was observed for average lifetime alcohol consumption and for all renal cancer subsites combined or for renal parenchyma subsite. The trend was not observed in hypertensive individuals and not significant in smokers. In conclusion, moderate alcohol consumption was associated with a decreased risk of renal cancer.

  19. Military Interoperable Digital Hospital Testbed (MIDHT) (United States)


    Wozniak, Joseph Dado , John Hargreaves, Lisa Pasierb 5d. PROJECT NUMBER and Thomas Simunich 5e. TASK NUMBER 5f. WORK UNIT...Considerations for future research are to see if medication errors could be segregated based on origination (i.e if drug dispensed from the robot vs the...These floors were chosen as a representative sample of CMMC based upon physical layout and patient composition. Given the size of MYMC (20-bed

  20. Toward Developing a Hydrodynamic Flow & Inundation Model of the Lower Pearl River (United States)


    AUTHOR(S) Paul McKay, Cheryl Ann Blain 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 73-6205-A9-5 7. PERFORMING ORGANIZATION...8/98) Prescribed by ANSI Sid. Z39.18 Toward Developing a Hydrodynamic Flow and Inundation Model of the Lower Pearl River Paul McKay and Cheryl... Ekman transport due to offshore forcing or surge tied to local storm events. Both channels of the lower Pearl are bordered by extensive floodplains

  1. 76 FR 19357 - Emergency Access Advisory Committee; Announcement of Date of Next Meeting (United States)


    ... when 9-1-1 call centers have the capacity to communicate with callers via voice, data, text and video... INFORMATION CONTACT: Cheryl King, Consumer and Governmental Affairs Bureau, (202) 418-2284 (voice) or (202... Security Bureau, (202) 418-2413 (voice), (e-mail): . SUPPLEMENTARY INFORMATION:...

  2. Steady Advances Against Cystic Fibrosis | NIH MedlinePlus the Magazine (United States)

    ... old Gunnar Esiason, son of former all-star NFL quarterback and current NFL commentator Boomer Esiason, hasn't let cystic fibrosis ( ... He and his parents—Cheryl Esiason and former NFL quarterback Boomer Esiason—are helping to fund research ...

  3. 76 FR 21741 - Emergency Access Advisory Committee; Announcement of Establishment, and of Members and Co... (United States)


    ...: Notice; correction. SUMMARY: The Federal Communication Commission published a document in the Federal... (e-mail). Correction In the Federal Register of December 15, 2010, in FR Doc. 2010... County Emergency Management--Bruce McFarlane Gallaudet University--Norman Williams Hearing, Speech...

  4. 78 FR 29209 - Revisions to Electric Reliability Organization Definition of Bulk Electric System and Rules of... (United States)


    ...: Before Commissioners: Jon Wellinghoff, Chairman; Philip D. Moeller, John R. Norris, Cheryl A. LaFleur... Holland, Michigan Board of Public Works (Holland); Dow Chemical Company (Dow); Electricity Consumers... for clarification. The ITC Companies filed a motion for leave to answer and answer to the Holland...

  5. Mathematics Formative Assessment: 75 Practical Strategies for Linking Assessment, Instruction, and Learning (United States)

    Keeley, Page; Tobey, Cheryl Rose


    Award-winning author Page Keeley and mathematics expert Cheryl Rose Tobey apply the successful format of Keeley's best-selling "Science Formative Assessment" to mathematics. They provide 75 formative assessment strategies and show teachers how to use them to inform instructional planning and better meet the needs of all students. Research shows…

  6. 77 FR 41172 - Trademark Board Manual of Procedure, Third Edition, Revision 1 (United States)


    ... Patent and Trademark Office Trademark Board Manual of Procedure, Third Edition, Revision 1 AGENCY: United... Trademark Office (``USPTO'') issued the third edition, revision 1, of the Trademark Board Manual of... 22313-1451, marked to the attention of Cheryl Butler, Senior Attorney and Editor, Trademark Board...

  7. 75 FR 1399 - Center for Scientific Review; Notice of Closed Meetings (United States)


    ... Metro Center, 7400 Wisconsin Avenue, Bethesda, MD 20814. Contact Person: Cheryl M. Corsaro, PhD... review and evaluate grant applications. Place: Hyatt Regency Bethesda, One Bethesda Metro Center, 7400... review and evaluate grant applications. Place: St. Gregory Hotel, 2033 M Street, NW., Washington,...

  8. Environmental Impact Statement for Proposed Closure of Eaker Air Force Base, Arkansas (United States)


    Connealy D.W. Lewis Mike Connealy Ron Lewis Richard Connell Ed Lippelman Deb Cooper Emmanuel Lofton Lynn H. Cox John Logan Phil D. Darnell Thomas W. Long...Stephen Gillespie Kristie Murphy Clarence Good Robin Myers Cheryl Gordon Jon Newman Donra Gray Eileen O’Neal Jan Gurley Shady Patton Edward Hale Todd

  9. 75 FR 29548 - Privacy Act of 1974; Notice of New System of Records (United States)


    ..., 2010. Cheryl M. Paige, Director, Office of Information Management. SYSTEM NAME: GSA/PBS- 8 (Electronic Document Management System - EDMS) SYSTEM LOCATION: Public Buildings Service (PBS), Enterprise Service... secure access to documents where and when they are needed. The system contains information related to...

  10. 76 FR 38604 - Rogue-Umpqua Resource Advisory Committee (United States)


    ... meeting will be held at 2900 NW. Stewart Parkway, Roseburg, Oregon, in the Umpqua National Forest... Umpqua National Forest Supervisor's Office, 2900 NW. Stewart Parkway, Roseburg, OR. Please call ahead to...: Cheryl Caplan, Public Affairs Officer, Umpqua National Forest, 541-957-3270 or...

  11. 77 FR 50460 - Rogue-Umpqua Resource Advisory Committee (United States)


    ....m. ADDRESSES: The meeting will be held at the Supervisor's Office of the Umpqua National Forest... inspect comments received at the Supervisor's Office for the Umpqua National Forest. Please call ahead to...: Cheryl Caplan, Public Affairs Officer, Umpqua National Forest, 541-957-3270,...

  12. 75 FR 37379 - Rogue-Umpqua Resource Advisory Committee (United States)


    .... ADDRESSES: The meeting will be held at 2900 NW Stewart Parkway, Roseburg, OR, in the Umpqua National Forest... inspection and copying. The public may inspect comments received at the Umpqua National Forest Supervisor's... FURTHER INFORMATION CONTACT: Cheryl Caplan, Public Affairs Officer, Umpqua National Forest,...

  13. 76 FR 49484 - Privacy Act of 1974; Notice of New System of Records (United States)


    ... number Personal home or mobile phone Personal e-mail addresses AUTHORITY FOR MAINTENANCE OF THE SYSTEM: 5... authentication to access Google Apps for Government implementation used by the GSA. Dated: July 26, 2011. Cheryl... system contains information needed to utilize two factor authentication to access Google Apps...

  14. 76 FR 1335 - Supplemental Standards of Ethical Conduct for Employees of the Federal Energy Regulatory Commission (United States)


    ... Commission 5 CFR Part 3401 Supplemental Standards of Ethical Conduct for Employees of the Federal Energy... the Office of Government Ethics (OGE), is amending the Supplemental Standards of Ethical Conduct for..., and Cheryl A. LaFleur. I. Background 1. The Office of Government Ethics (OGE) has issued rules...

  15. 76 FR 21393 - Agency Information Collection Activities: Proposed Collection; Comment Request (United States)


    ...; Bureau of Ocean Energy Management, Regulation and Enforcement; Attention: Cheryl Blundon; 381 Elden... techniques or other forms of information technology. Agencies must also estimate the non-hour cost burdens to... with the information collection; (iii) for reasons other than to provide information or keep...

  16. The Ecology of Hope: Natural Guides to Building a Children and Nature Movement (United States)

    Charles, Cheryl


    Cheryl Charles, Ph.D gave the 2009 Paul F-Brandwein Lecture. The lecture addresses the impact of children's disconnect from the natural world in their everyday lives. Co-founder of the Children & Nature Network (C&NN) with Richard Louv, author of "Last Child in the Woods: Saving Our Children from Nature-Deficit Disorder" (2005/2008), the author…

  17. Steps to the Future. Dental Hygiene Education and Practice Workshop II Proceedings (Louisville, Kentucky, April 25-27, 1985). (United States)

    American Dental Hygienists' Association, Chicago, IL.

    The proceedings of the second in a series of workshops on dental hygiene education and practice are presented. The opening remarks are by Cheryl Westphal. Papers categorized as "Considerations for the Professionalization of Dental Hygiene" are as follows: "Socio-Economic Viewpoint" (Gary Gaumer); "Political Science Viewpoint" (Lelia Helms);…

  18. 77 FR 63316 - Privacy Act of 1974; Notice of New System of Records (United States)


    .... Cheryl M. Paige, Director, Office of Information Management. GSA/CIO-3 SYSTEM NAME: GSA's Enterprise...: Enterprise Application Services (EAS) is a singular component system managed by the Applied Solutions... datacenters hosted by GSA in Kansas City (Region 6) and Fort Worth (Region 7) as well as Cloud components...

  19. 75 FR 28253 - Privacy Act of 1974; Notice of new System of Records (United States)


    ... track and manage the Art in Architecture program, the National Artist Registry and the fine arts... in Architecture and Fine Arts programs. Dated: May 13, 2010. Cheryl M. Paige, Director, Office of... are located at the vendor location in PBS Enterprise Service Center (ESC) facility located at 14426...

  20. 77 FR 43578 - Applications for New Awards; American Overseas Research Centers Program (United States)


    ... Contact For Further Information Contact: Cheryl E. Gibbs, International and Foreign Language Education... vary depending on a variety of factors, including the size of the application and the speed of your..., gender, age, or disability; (ii) The extent to which the services to be provided by the proposed...

  1. Identifying and Validating Selection Tools for Predicting Officer Performance and Retention (United States)


    developed for use in the validation analyses. Criterion Measures Criterion measurement methods were organized into four categories...Teresa L. Russell, Editor Cheryl J. Paullin, Editor Human Resources Research Organization Peter J. Legree, Editor Robert N. Kilcullen, Editor...for the Department of the Army by Human Resources Research Organization Technical review by Rebekkah Beeco, U.S. Army Research Institute

  2. 12th Annual Science and Engineering Technology Conference/DoD TECH Exposition (United States)


    SPAWAR CDR Will Hesse , USN (Ret) Scott Health & Safety Dr. Ed Hibsman SPAWAR Mr. Larry Hill CAS, Inc. Mrs. Cheryl Holbrook U.S. Army Space and Missile... Herman Rediess Science & Technology Directorate, DHS CAPT Brett Reissener, USN (Ret) Concurrent Technologies Corporation Ms. Denise Rhea-McKenzie Mission

  3. Return to the little kingdom Steve Jobs, the creation of Apple, and how it changed the world

    CERN Document Server

    Moritz, Michael


    Almost thirty years ago, Michael Moritz, then a young journalist at Time magazine, was allowed exclusive access to the inner workings of a cutting-edge technology company to tell the story of its first decade in business. The Little Kingdom: The Private Story of Apple Computer brought readers into the childhood homes of Steve Jobs and Steve Wozniak, showed how they dropped out of college and founded Apple in 1976, and charted the company's rise from basement brainstorming to colossal empire. Now, after spending almost twenty-five years at Sequoia Capital, the much admired private investm

  4. Hackers Heroes of the Computer Revolution - 25th Anniversary Edition

    CERN Document Server

    Levy, Steven


    This 25th anniversary edition of Steven Levy's classic book traces the exploits of the computer revolution's original hackers -- those brilliant and eccentric nerds from the late 1950s through the early '80s who took risks, bent the rules, and pushed the world in a radical new direction. With updated material from noteworthy hackers such as Bill Gates, Mark Zuckerberg, Richard Stallman, and Steve Wozniak, Hackers is a fascinating story that begins in early computer research labs and leads to the first home computers. Levy profiles the imaginative brainiacs who found clever and unorthodox sol

  5. Outpatient Preoperative Education Needs Identified by Nurses and Patients. (United States)


    PREOPERATIVE EDUCATION NEEDS IDENTIFIED BY NURSES AND PATIENTS Cheryl Anne Reilly APPROVED: Supervising Prdessor Date APPROVED: / "Sanfor• Miller , P... anesthesiologist will visit them before 5 4 3 2 1 surgery to discuss what anesthesia would be used. 27. Their incision may pull, bum, or itch while it is 5 4...such as, giving me an injection & asking me to empty my bladder. 26. An anesthesiologist would visit me before Yes No 5 4 3 2 1 surgery to discuss

  6. A Study of Critical Thinking Training in the Army Contracting Workforce (United States)


    Running head: CRITICAL THINKING TRAINING 1 A Study of Critical Thinking Training in the Army Contracting Workforce Cheryl L. Jones...7 April 2016, U.S. Army Contracting Command CRITICAL THINKING TRAINING 2 Approval Page Title: A Study of Critical Thinking Training in...submitted for Journal Publication: CRITICAL THINKING TRAINING 3 Acknowledgements I would like to acknowledge the efforts of the U.S. Army

  7. A History of the Waterways Experiment Station 1929-1979 (United States)


    Matthews, Margaret S. McNeal, Linda S. Liggins, Edward L. Mattingly, Betty P. McPhearson, James A. Lindley, Oscar E. Maxey, John L. McVay, Mark K...Lloyd, Cheryl M. May, J ohn R. Meyer, Marvin P. Lloyd, Michael K. Mayfield, James, Jr. Miller, Charles A. Lockard, Susan Mayfield , Oscar , Jr...D. Sherlock, Ann R. Smith, Patricia A. Rubin de Ia Borbolla , GeorgeS. Sherlock, James A. Smith, Perry A. Rush, Edgar S. Sherman, Walter C., Jr

  8. Book review: Islam, alienation, and violence: case studies of the men at the margins



    Europe’s Angry Muslims traces the routes, expectations and destinies of immigrant parents and the plight of their children, transporting the reader from the immigrants’ ancestral villages to their strange new-fangled enclaves in Europe. Cheryl Brumley finds that in the crowded world of terrorism literature, Leiken’s book especially stands out for focussing on individual tales of Europe’s second generation Muslim migrants. \\ud \\ud Europe’s Angry Muslims: The revolt of the second generation. Ro...

  9. Book review: can the newspaper survive amidst Youtube, lone bloggers and Wikileaks?\\ud



    Page One explores journalism’s big shake-up and takes on the cause of reuniting journalism with its true civic purpose. After reading this collection of essays, Cheryl Brumley reflects that there remains not enough consensus, nor enough collaboration between all constituents of the media world to save itself from slipping further into untenable business practices.\\ud \\ud Page One: Inside the New York Times. Edited by David Folkenflik. Public Affairs. June 2011.\\ud \\ud

  10. Calculating Depth of Closure Using WIS Hindcast Data (United States)


    budgets, numerical modeling of coastal geomorphological change, and beach nourishment design (Nicholls et al. 1996). One application of this tool is Katherine E. Brutsché, James Rosati III, Cheryl E. Pollock, and Brian C. McFall PURPOSE: In this Coastal and Hydraulics Engineering Technical... Study (WIS) hindcast stations along the United States coastlines. The results summarized in this CHETN are available in the form of a spreadsheet on

  11. Evaluating Sediment Mobility for Siting Nearshore Berms (United States)


    Berms by Brian C. McFall, S. Jarrell Smith, Cheryl E. Pollock, James Rosati III, and Katherine E. Brutsché PURPOSE: This Coastal and Hydraulics... studies to compare multiple placement sites. Presently, a Matlab script is available to perform the calculations using both methods. Future development...estimate the potential volume of sediment that a placement operation might yield to beneficially nourish a wetland or nearshore region, thereby allowing

  12. An Analysis of Organizational and Funding Alternatives for the Armed Force Institute of Pathology (United States)


    P. Clark • Murrel D. Coast • Alan J. Marcus • Cesar A. Perez • Cheryl B. Rosenblum CNA 4825 Mark Center Drive • Alexandria, Virginia 22311-1850...Environmental Detachments (Charleston SC and Vallejo CA) . . . . . . . . . . . 75 Asset sale . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 Transition...Charleston SC and Vallejo CA) In 1996, as a result of BRAG 1994, the Naval Sea Systems Command (NAVSEA) established two teams, or detachments, of Navy

  13. Virtual Environments Overview (United States)


    Mind’s Hidden Complexities. New York : Basic Books. Fujita, M., Krugman , P., Venables, A. (1999). The Spatial Economy: Cities, Regions and...facilitated our entry into the virtual world arena: Neale Barrett, Doug McDavid, Jean Paul Jacob, Cheryl Kieliszewski and, until he left for Linden Lab...Dave Kamalsky. Also, we are very grateful for the tremendous support from our colleagues in the Almaden Services Research department, especially Paul

  14. Shallow Water Dynamics in the Arabian Gulf and Gulf of Oman (United States)


    Shallow Water Dynamics in the Arabian Gulf and Gulf of Oman Dr. Cheryl Ann Blain Naval Research Laboratory, Ocean Dynamics and Prediction Branch...of a circulation model for the Arabian Gulf and connecting waters that realistically predicts the complex, 3-D circulation and mixing patterns in the...forcings in the region, a strong evaporative flux, seasonal wind forcing, and freshwater river discharge. Not only are realistic current fields sought but

  15. Smoking Cessation/Prevention in the Air Force: How Adequate (United States)


    FNP , Com. Member Approval DaW APPROVED: F.G. Abdellah, EdD, ScD, RN, FAAN Date Dean CURRICULUM VITAE Name: Cheryl Anita Udensi Permanent Address...sample of charts and client interview was employed to compare providers’ documented practice protocols with established guidelines set by the Department of...validity in smoking cessation practices was utilized. A pilot study was done to determine intercoder reliability. Descriptive statistics were utilized to

  16. Erodibility Study of Passaic River Sediments Using USACE Sedflume (United States)


    Program, Dr. Todd S. Bridges, Program Manager. The report was written by Thomas D. Borrowman, Environmental Engi- neering Branch ( EEB ), Environmental...FSPD), CHL; and Larry Caviness, Field Data Collect and Analysis Branch, FSPD, CHL. Laboratory work was conducted by Richard Hudson, EEB . Cheryl M...Lloyd, EEB , assisted in the preparation of the report. This study was conducted under the direct supervision of Bruce A. Ebersole, Chief, FSPD, and

  17. A One Health overview, facilitating advances in comparative medicine and translational research



    Table of contents A1 One health advances and successes in comparative medicine and translational research Cheryl Stroud A2 Dendritic cell-targeted gorilla adenoviral vector for cancer vaccination for canine melanoma Igor Dmitriev, Elena Kashentseva, Jeffrey N. Bryan, David T. Curiel A3 Viroimmunotherapy for malignant melanoma in the companion dog model Jeffrey N. Bryan, David Curiel, Igor Dmitriev, Elena Kashentseva, Hans Rindt, Carol Reinero, Carolyn J. Henry A4 Of mice and men (and dogs!): ...

  18. Phase 2 Studies: Impacts of Commercial Navigation Traffic on Freshwater Mussels at the W.H. Zimmer Station, 1989-90 Baseline Studies (United States)


    informatiOn Operations and Reports 121 Jeffenrson Oeiiis Highway. Suitt t204. Aclington, VA 222024302. and to the Office Of Management and Budget...Preface . Conversion Factors, Non-SI to SI Units of Measurement. .. .. .. ... vii 1- Introduction ...................... Background...was provided by Mr. Scott Schermerhorn , Ms. Cheryl Tansky, and Dr. Albert Burky, all with the University of Dayton, and Ms. Sarah Wilkerson, WES Dr

  19. Welcome aboard (but don't change a thing). (United States)

    McNulty, Eric


    Cheryl Hailstrom, the CEO of Lakeland Wonders, a manufacturer of high-quality wooden toys, is the first person outside the Swensen family to hold the top job. But she's not a stranger to this 94-year-old company: She'd been the COO of one of its largest customers and had worked with Lakeland to develop many best-selling products. Wally Swensen IV, the previous CEO, chose Cheryl because she knew how to generate profits and because he believed her energy and enthusiasm could take the company to the next level. Yet here she is, nearing her six-month anniversary, wondering why her expansive vision for the company isn't taking hold. She's tried to lead by example: traveling a pounding schedule to visit customers, setting aggressive project deadlines, and proposing a bonus schedule. She has a plan to reach the board's growth goals--going beyond Lakeland's core upscale market and launching into the midmarket with an exclusive toy contract with a new customer. The problem is that while Cheryl's senior managers are giving her the nod on the surface, they're all really dragging their feet. Some fear that offshore outsourcing will hurt their brand, not to mention make for tricky union negotiations. Others are balking at trying a new design firm. Is Cheryl pushing too much change too quickly? Should she bring in outsiders to speedily adopt the changes she envisions and overhaul Lakeland's corporate culture? Or should she keep trying to work with the current team? Commentators Kathleen Calcidise of Apple Retail Stores; executive coach Debra Benton; Dan Cohen, coauthor of The Heart of Change; and consultant Nina Aversano offer advice in this fictional case study.

  20. The view from the observatory: history is too important to be left to the historians (United States)

    Osterbrock, Donald E.

    A research astronomer and historian of astronomy begins this paper with a statement on his views of the latter subject. It helps anyone who wishes to understand its history to know and understand astronomy. History must be based on facts, which archives, scientific papers, and books can provide. Immersion in a field like astronomy makes one better qualified to understand what others have done in that field, and to write about it, as Henrik Ibsen, Ernest Hemingway, Barbara Tuchman, and John Grisham have all stated and proved by example. The second part of the paper is a progress report on the author's current project, the life and scientific career of the early American astronomer and solar physicist Charles A. Young (1834-1908). Astronomy was very different in his "small-telescope era", but there are many modern resonances in his problems and their solutions.

  1. Unmet needs of patients with narcolepsy: perspectives on emerging treatment options

    Directory of Open Access Journals (Sweden)

    Wozniak DR


    Full Text Available Dariusz R Wozniak, Timothy G Quinnell Respiratory Support and Sleep Centre, Papworth Hospital, Cambridge, UK Abstract: The treatment options currently available for narcolepsy are often unsatisfactory due to suboptimal efficacy, troublesome side effects, development of drug tolerance, and inconvenience. Our understanding of the neurobiology of narcolepsy has greatly improved over the last decade. This knowledge has not yet translated into additional therapeutic options for patients, but progress is being made. Some compounds, such as histaminergic H3 receptor antagonists, may prove useful in symptom control of narcolepsy. The prospect of finding a cure still seems distant, but hypocretin replacement therapy offers some promise. In this narrative review, we describe these developments and others which may yield more effective narcolepsy treatments in the future. Keywords: cataplexy, hypocretin, H3 antagonist, GABA-B agonists, immunotherapy 

  2. Rio de Janiero is coming to terms with the brutality of urban transformation that can come with mega-events like the Olympics



    Over the next two years, Rio de Janiero is set to host the world’s two most premiere sporting events, the 2014 Football World Cup, and the 2016 Summer Olympic Games. At the end of 2013 Cheryl Brumley travelled to Brazil to investigate how Rio is transforming ahead of these sporting mega-events. As part of USApp’s coverage of the North American neighborhood, she discusses how she found both city and local leaders struggling to maintain a balancing act between effective urban transformation and...

  3. The Science of Science Policy: A Federal Research Roadmap (United States)


    economists such as Robert Solow (who won the Nobel Prize in Economics for his work on the impact of innova on on economic growth) have developed...Kaye Husbands-Fealing, Former Co-Chair Melanie Roberts Centers for Disease Control and Preven on Vilma Carande-Kulis Central Intelligence Agency H...Agriculture John King Robert MacDonald Sara Mazie U.S. Geological Survey Carl Shapiro U.S. Department of Veterans Aff airs Cheryl Oros T S S P : A

  4. Size- and charge-dependent non-specific uptake of PEGylated nanoparticles by macrophages


    Dickerson JH; Maron DJ; Jerome WG; Thomas SN; Lau CM; Yu SS; Hubbell JA; Giorgio TD


    Shann S Yu1,2, Cheryl M Lau1, Susan N Thomas3, W Gray Jerome4, David J Maron5, James H Dickerson2,6, Jeffrey A Hubbell3, Todd D Giorgio1,2,7,81Department of Biomedical Engineering, Vanderbilt University, Nashville, 2Vanderbilt Institute of Nanoscale Science and Engineering, Nashville, TN, USA; 3Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 4Department of Pathology, Vanderbilt University Medical Center, Nashville,...

  5. Uncovering student thinking about mathematics in the common core, grades 6-8 25 formative assessment probes

    CERN Document Server

    Tobey, Cheryl Rose


    Pinpoint and reverse math misconceptions with laser-like accuracyQuickly and reliably uncover common math misconceptions in Grades 6-8 with these convenient and easy-to-implement diagnostic tools! Bestselling authors Cheryl Tobey and Carolyn Arline provide 25 new assessment probes that pinpoint subconcepts within the new Common Core Standards for Mathematics to promote deep learning and expert math instruction--while learning is already underway.Completely CCSM aligned, these grade-specific probes eliminate the guesswork and help teachers: Systematically address conceptual and procedural mistakes Help students better understand areas of struggle Plan targeted instruction that covers Grades 6-8 CCSM mathematical processes and proficiencies.

  6. The Power of Comparative Physiology: Evolution, Integration and Applied (United States)


    C.A.S. Turnbull and M.D. store development in nursing harbor seal Dearing. Univ. of Utah. pups. C.A. Creelman , J.M. Burns and 13 7.13 Photoperiod...Cheryl Anne Creelman ’, Jennifer M Bums’, Jason F Schroer’: ’University of Alaska Trude Eva Reich, Paul Keim, Stan L. Lindstedt: Northern Arizona...7.52 Creelman , C., 7.25 Gardner, M., 7.14 .IHsiyh, S., 46.24 Baker. P., 46.19 Crossley 11, D., 45.5 Garland, Jr., T., 2.3, 26. 1, Huierma, H., 46.24

  7. Experimental test of whether electrostatically charged micro-organisms and their spores contribute to the onset of arcs across vacuum gaps

    Energy Technology Data Exchange (ETDEWEB)

    Grisham, L. R.; Halle, A. von; Carpe, A. F.; Gilton, K. R.; Rossi, Guy; Stevenson, T. N. [Princeton University Plasma Physics Laboratory, P. O. Box 451, Princeton, New Jersey 08543 (United States)


    Recently it was proposed [L. R. Grisham et al. Phys. Plasmas 19, 023107 (2012)] that one of the initiators of vacuum voltage breakdown between conducting electrodes might be micro-organisms and their spores, previously deposited during exposure to air, which then become electrostatically charged when an electric potential is applied across the vacuum gap. This note describes a simple experiment to compare the number of voltage-conditioning pulses required to reach the nominal maximum operating voltage across a gap between two metallic conductors in a vacuum, comparing cases in which biological cleaning was done just prior to pump-down with cases where this was not done, with each case preceded by exposure to ambient air for three days. Based upon these results, it does not appear that air-deposited microbes and their spores constitute a major pathway for arc initiation, at least for exposure periods of a few days, and for vacuum gaps of a few millimeters, in the regime where voltage holding is usually observed to vary linearly with gap distance.

  8. Neuropsychological and neurophysiological insights into hoarding disorder

    Directory of Open Access Journals (Sweden)

    Grisham JR


    Full Text Available Jessica R Grisham, Peter A Baldwin School of Psychology, University of New South Wales, Sydney, Australia Abstract: Hoarding disorder (HD is associated with significant personal impairment in function and constitutes a severe public health burden. Individuals who hoard experience intense distress in discarding a large number of objects, which results in extreme clutter. Research and theory suggest that hoarding may be associated with specific deficits in information processing, particularly in the areas of attention, memory, and executive functioning. There is also growing interest in the neural underpinnings of hoarding behavior. Thus, the primary aim of this review is to summarize the current state of evidence regarding neuropsychological deficits associated with hoarding and review research on its neurophysiological underpinnings. We also outline the prominent theoretical model of hoarding and provide an up-to-date description of empirically based psychological and medical treatment approaches for HD. Finally, we discuss important future avenues for elaborating our model of HD and improving treatment access and outcomes for this disabling disorder. Keywords: hoarding, information processing, neuropsychology, neurophysiology, treatment

  9. 英国畅销书排行榜(2014年6月29日~7月27日)

    Institute of Scientific and Technical Information of China (English)


    <正>【思羽评榜】约翰·格林的《无比美妙的痛苦》依旧在榜单中表现抢眼,在本期的英国畅销书排行榜前十位中,共有两个版本的《无比美妙的痛苦》上榜,分别位于第一与第四位。老牌作家约翰·格里森姆(John Grisham)的2013年新作《悬铃木道》(SYCAMORE ROW)位于榜单第二位。该书是他的代表作《杀戮时刻》的续作,主人公依旧是律师杰克·布里根斯,故事发生在《杀戮时刻》中的庭审结束的三年之后。

  10. Vacuum ultraviolet photoionization of carbohydrates and nucleotides

    Energy Technology Data Exchange (ETDEWEB)

    Shin, Joong-Won, E-mail: [Division of Science, Governors State University, University Park, Illinois 60484-0975 (United States); Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523-1872 (United States); Bernstein, Elliot R., E-mail: [Department of Chemistry, Colorado State University, Fort Collins, Colorado 80523-1872 (United States)


    Carbohydrates (2-deoxyribose, ribose, and xylose) and nucleotides (adenosine-, cytidine-, guanosine-, and uridine-5{sup ′}-monophosphate) are generated in the gas phase, and ionized with vacuum ultraviolet photons (VUV, 118.2 nm). The observed time of flight mass spectra of the carbohydrate fragmentation are similar to those observed [J.-W. Shin, F. Dong, M. Grisham, J. J. Rocca, and E. R. Bernstein, Chem. Phys. Lett. 506, 161 (2011)] for 46.9 nm photon ionization, but with more intensity in higher mass fragment ions. The tendency of carbohydrate ions to fragment extensively following ionization seemingly suggests that nucleic acids might undergo radiation damage as a result of carbohydrate, rather than nucleobase fragmentation. VUV photoionization of nucleotides (monophosphate-carbohydrate-nucleobase), however, shows that the carbohydrate-nucleobase bond is the primary fragmentation site for these species. Density functional theory (DFT) calculations indicate that the removed carbohydrate electrons by the 118.2 nm photons are associated with endocyclic C–C and C–O ring centered orbitals: loss of electron density in the ring bonds of the nascent ion can thus account for the observed fragmentation patterns following carbohydrate ionization. DFT calculations also indicate that electrons removed from nucleotides under these same conditions are associated with orbitals involved with the nucleobase-saccharide linkage electron density. The calculations give a general mechanism and explanation of the experimental results.

  11. The prevalence of compulsive hoarding and its association with compulsive buying in a German population-based sample. (United States)

    Mueller, Astrid; Mitchell, James E; Crosby, Ross D; Glaesmer, Heide; de Zwaan, Martina


    The aims of the study were to estimate the prevalence rate of compulsive hoarding, and to determine the association between compulsive hoarding and compulsive buying in a nationally representative sample of the German population (N = 2307). Compulsive hoarding was assessed with the German version of the Saving Inventory-Revised (SI-R; Frost, R.O., Steketee, G., & Grisham, J. (2004). Measurement of compulsive hoarding: saving inventory-revised. Behaviour Research and Therapy, 42, 1163-1182.). The point prevalence of compulsive hoarding was estimated to be 4.6%. Individuals with compulsive hoarding did not differ significantly from those without compulsive hoarding regarding age, gender, and other sociodemographic characteristics. Significant correlations were found between the compulsive hoarding and the compulsive buying measures. Participants with compulsive hoarding reported a higher propensity to compulsive buying than respondents without hoarding. About two thirds of participants classified as having compulsive hoarding were also defined as suffering from compulsive buying. In summary, these results suggest that compulsive hoarding may be relatively prevalent in Germany and they confirm the close association between compulsive hoarding and compulsive buying through the investigation of a large scale representative sample.

  12. Experimental Test Of Whether Electrostatically Charged Micro-organisms And Their Spores Contribute To The Onset Of Arcs Across Vacuum Gaps

    Energy Technology Data Exchange (ETDEWEB)

    none,; Grisham, Larry R.


    Recently it was proposed [L.R. Grisham, A. vonHalle, A.F. Carpe, Guy Rossi, K.R. Gilton, E.D. McBride, E.P. Gilson, A. Stepanov, T.N. Stevenson, Physics of Plasma 19 023107 (2012)] that one of the initiators of vacuum voltage breakdown between condu cting electrodes might be micro-organisms and their spores, previously deposited during exposure to air, which tnen become electrostatically charged when an electric potential is applied across the vacuum gap. The note describes a simple experiment to compare the number of voltage-conditioning pulses required to reach the nominal maxium operating voltage across a gap between two metallic conductors in a vacuum, comparing cases in which biological cleaning was done just prior to pump-down with cases where this was not done, with each preceded by exposure to ambient air for three days. Based upon these results, it does not appear that air-deposited microbes and their spores constitute a major pathway for arc initiation, at least for exposure periods of a few days, and for vacuum gaps of a few millimeters, in the regime where voltage holding is usually observed to vary linearly with gap distance

  13. A small source in Q2237+0305?

    CERN Document Server

    Wyithe, J S B; Turner, E L


    Microlensing in Q2237+0305 between 1985 and 1995 (eg. Irwin et al. 1989; Corrigan et al. 1991; Ostensen et al. 1996) has been interpreted in two different ways; as microlensing by stellar mass objects of a continuum source having dimensions significantly smaller than the microlens Einstein radius (ER) (eg. Wambsganss, Paczynski & Schneider 1990; Rauch & Blandford 1991), and as microlensing by very low mass objects of a source as large as 5 ER (Refsdal & Stabell 1993; Haugan 1996). In this paper we present evidence in favour of a small source. Limits on the source size (in units of ER) are obtained from the combination of limits on the number of microlens Einstein radii crossed by the source during the monitoring period with two separate light-curve features. Firstly, recently published monitoring data (Wozniak et al. 2000; OGLE web page) show large variations (~0.8-1.5 magnitudes) between image brightnesses over a period of 700 days or ~15% of the monitoring period. Secondly, the 1988 peak in the ...

  14. Stakeholder Perceptions of Barriers and Solutions to Significant Expansion of Postsecondary Enrollment Options for High School Students

    Directory of Open Access Journals (Sweden)

    Carl Wozniak


    Full Text Available Post-secondary experiences for students still in high school have been promoted as a means to increase academic rigor and create a better-trained workforce. Yet little is known regarding supports needed to significantly increase such options. This study obtained input from 411 stakeholders in one Midwestern state, including 201 district superintendents, 181 high school principals, and 23 college dual enrollment officers regarding their use of these options, their perceptions of barriers to program expansion, and their ranking of possible solutions to overcome the barriers. Findings demonstrate that all parties find postsecondary options of value, with traditional dual enrollment the most used option. Although all groups identified funding as a primary barrier, other systemic barriers were of great concern. Participants suggest that expansion of Advanced Placement and early and middle college programs, financial assistance for dually enrolled students, and increased program availability for career and technical options would be beneficial.Wozniak, Carl, (2012. Stakeholder Perceptions of Barriers and Solutions to Significant Expansion of Postsecondary Enrollment Options for High School Students. 8(2. Retrieved from .

  15. Introduction to Biofilms Thematic Minireview Series. (United States)

    Allewell, Norma M


    The biofilms that many bacteria and fungi produce enable them to form communities, adhere tightly to surfaces, evade host immunity, and resist antibiotics. Pathogenic microorganisms that form biofilms are very difficult to eradicate and thus are a frequent source of life-threatening, hospital-acquired infections. This series of five minireviews from the Journal of Biological Chemistry provides a broad overview of our current understanding of biofilms and the challenges that remain. The structure, biosynthesis, and biological function of the biofilms produced by pathogenic fungi are the subject of the first article, by Sheppard and Howell. Gunn, Bakaletz, and Wozniak focus on the biochemistry and structure of bacterial biofilms, how these structures enable bacteria to evade host immunity, and current and developing strategies for overcoming this resistance. The third and fourth articles present two of the best understood cell signaling pathways involved in biofilm formation. Valentini and Filloux focus on cyclic di-GMP, while Kavanaugh and Horswill discuss the quorum-sensing (agr) system and the relationship between quorum sensing and biofilm formation. Mechanisms of antibiotic resistance, particularly the role of efflux pumps and the development of persister cells, are the topics of the final article by Van Acker and Coenye. The advances described in this series guarantee that ongoing interdisciplinary and international efforts will lead to new insights into the basic biology of biofilm formation, as well as new strategies for therapeutic interventions.

  16. VizieR Online Data Catalog: 86 new variables in Andromed (Dimitrov+, 2007) (United States)

    Dimitrov, D.; Popov, V.


    One of the most extensive sky surveys in the recent years is the Northern Sky Variability Survey (NSVS, Wozniak et al., 2004AJ....127.2436W). Light curves of about 14000000 objects with instrumental magnitudes between 8 and 15.5 are included in the database of that survey, for the period April 1999 - March 2000, covering all of the Northern hemisphere and reaching DE=-38° in the South. To look for different types of variables, we rely only upon internal NSVS data. We select an area on the sky and check for variability in the NSVS database. Our test area covers 46 deg in Andromeda, its coordinates are: 23:00<=RA<=23:45 and 43:30<=DE<=29:30 (2000.0). The galactic latitude is in the -10° - -20° range. The total number of NSVS light curves in this area is and every star has between 1 and 4 light curves, the mean value being 1.875 light curves per star. (2 data files).

  17. Early-Time Observations of the GRB 050319 Optical Transient

    CERN Document Server

    Quimby, R M; Yost, S A; Aharonian, F; Akerlof, C W; Alatalo, K; Ashley, M C B; Goegues, E; Guever, T; Horns, D; Kehoe, R L; Kiziloglu, U; McKay, T A; Oezel, M; Phillips, A; Schaefer, B E; Smith, D A; Swan, H F; Vestrand, W T; Wheeler, J C; Wren, J; Kiziloglu, Ue.


    We present the unfiltered ROTSE-III light curve of the optical transient associated with GRB 050319 beginning 4 s after the cessation of gamma-ray activity. We fit a power-law function to the data using the revised trigger time given by Chincarini et al. (2005), and a smoothly broken power-law to the data using the original trigger disseminated through the GCN notices. Including the RAPTOR data from Wozniak et al. (2005), the best fit power-law indices are alpha=-0.854 (+/- 0.014) for the single power-law and alpha_1=-0.364 (+/- 0.020), alpha_2= -0.881 (+/- 0.030), with a break at t_b = 418 (+/- 30) s for the smoothly broken fit. We discuss the fit results with emphasis placed on the importance of knowing the true start time of the optical transient for this multi-peaked burst. As Swift continues to provide prompt GRB locations, it becomes more important to answer the question, "when does the afterglow begin" to correctly interpret the light curves.

  18. TEDxBrussels broadcast live at CERN

    CERN Multimedia

    Claudia Marcelloni, TEDxCERN organiser


    In order to give you a taste of a TEDx event, the team of TEDxCERN will show the live webcast of TEDxBrussels at the CERN main restaurant on November 12th from 9 a.m. to 10:30 a.m. and from 2 p.m to 7 p.m.  Come and discover the event, in preparation for TEDxCERN, which will take place in May next year.     This year the theme for TEDxBrussels is Bits, Atoms, Neurons, Genes (BANG BANG). The digital world and the real world are interconnected like never before. You can send off online for a personal genome readout and control physical objects with your mind. Computer thinking is driving medicine, music and play. With brain-computer interfaces now used in nuclear power stations and bio hackers doing lab biology in their garages, BANG BANG is a concept whose time has come. BANG BANG means the evolving mesh of ideas and practices, a rich mix of citizens, scientists and culture. Among the speakers are Steve Wozniak, Mitch Altman, Neelie Kroes, Xavier Damman, Zoe Laughli...

  19. 《家事的抚慰》:家事的抚慰从何处来

    Institute of Scientific and Technical Information of China (English)



    雪瑞·孟德森(Cheryl Mendelson),美国作家,出生于宾夕法尼亚州格林县农家,先后获得罗切斯特大学哲学博士学位和哈佛大学法学院法学博士学位。曾在纽约从事律师工作,并在普渡大学和哥伦比亚大学巴纳德学院教授哲学。1999年,她出版了《家事的抚慰:食物、衣物,以及合理的家事计划》(Home Comforts:The Art and Science of Keeping House)。

  20. Reel success creating demo reels and animation portfolios

    CERN Document Server

    Cabrera, Cheryl


    Are you an animator looking to get your foot in the door to the top studios?It's tough if you don't have a demo reel and portfolio that reflects your unique style and incredible talents.  The reception of that reel will make or break you; so it's no wonder that creating a demo reel can be such a daunting task.  Reel Success by Cheryl Cabrera can help.  This book guides you into putting the right content into your portfolio, how to cater to the right audience, and how to harness the power of social media and network effectively.  Accompanied by case studies of actual students

  1. An African theory of bioethics: reply to MacPherson and Macklin. (United States)

    Metz, Thaddeus


    In a prior issue of Developing World Bioethics, Cheryl Macpherson and Ruth Macklin critically engaged with an article of mine, where I articulated a moral theory grounded on indigenous values salient in the sub-Saharan region, and then applied it to four major issues in bioethics, comparing and contrasting its implications with those of the dominant Western moral theories, utilitarianism and Kantianism. In response to my essay, Macpherson and Macklin have posed questions about: whether philosophical justifications are something with which bioethicists ought to be concerned; why something counts as 'African'; how medicine is a moral enterprise; whether an individual right to informed consent is consistent with sub-Saharan values; and when thought experiments help to establish firm conclusions about moral status. These are important issues for the field, and I use this reply to take discussion of them a step or two farther, defending my initial article from Macpherson's and Macklin's critical questions and objections. © 2010 Blackwell Publishing Ltd.

  2. A qualitative meta-synthesis and theory of postpartum depression. (United States)

    Mollard, Elizabeth K


    To synthesize existing qualitative literature on the first-hand experiences of women suffering from postpartum depression (PPD), to uncover potential common themes, a meta-synthesis of 12 qualitative studies using Noblit and Hare's 7-phase model of meta-ethnography was used. Four themes were discovered: crushed maternal role expectation, going into hiding, loss of sense of self, intense feelings of vulnerability, plus practical life concerns. A preliminary theory of PPD as a 4-step process is proposed, based on the relationships between the themes in this meta-synthesis. This 4-step process is compared and contrasted with Cheryl Tatano Beck's 4-stage theory of PPD "Teetering on the Edge". This meta-synthesis and theory offers a significant contribution to the literature in helping identify PPD distinctly from depression outside of the postpartum period, and deserves further study.

  3. Distributed plot-making

    DEFF Research Database (Denmark)

    Jensen, Lotte Groth; Bossen, Claus


    different socio-technical systems (paper-based and electronic patient records). Drawing on the theory of distributed cognition and narrative theory, primarily inspired by the work done within health care by Cheryl Mattingly, we propose that the creation of overview may be conceptualised as ‘distributed plot......-making’. Distributed cognition focuses on the role of artefacts, humans and their interaction in information processing, while narrative theory focuses on how humans create narratives through the plot construction. Hence, the concept of distributed plot-making highlights the distribution of information processing...... between different social actors and artefacts, as well as the filtering, sorting and ordering of such information into a narrative that is made coherent by a plot. The analysis shows that the characteristics of paper-based and electronic patient records support or obstruct the creation of overview in both...

  4. Extraction studies. Final report, May 6, 1996--September 30, 1997

    Energy Technology Data Exchange (ETDEWEB)



    During the first week of this effort, an Alpkem RFA-300 4-channel automated chemical analyzer was transferred to the basement of building 42 at TA-46 for the purpose of performing extraction studies. Initially, this instrumentation was applied to soil samples known to contain DNA. Using the SFA (Segmented Flow Analysis) technique, several fluidic systems were evaluated to perform on-line filtration of several varieties of soil obtained from Cheryl Kuske and Kaysie Banton (TA-43, Bldg. 1). Progress reports were issued monthly beginning May 15, 1996. Early in 1997 there was a shift from the conventional 2-phase system (aqueous + air) to a 3-phase system (oil + aqueous + air) to drastically reduce sample size and reagent consumption. Computer animation was recorded on videotape for presentations. The time remaining on the subcontract was devoted to setting up existing equipment to incorporate the 3rd phase (a special fluorocarbon oil obtained from DuPont).

  5. Cytoplasmic Streaming - Skylab Student Experiment ED-63 (United States)


    This chart describes the Skylab student experiment (ED-63), Cytoplasmic Streaming, proposed by Cheryl A. Peitz of Arapahoe High School, Littleton, Colorado. Experiment ED-63 was to observe the effect of zero-gravity on cytoplasmic streaming in the aquatic plant named Elodea, commonly called water weed or water thyme. The phenomenon of cytoplasmic streaming is not well understood, but it is recognized as the circulation mechanism of the internal materials or cytoplasm of a cell. Cytoplasm is a gelatinous substance that has the ability to change its viscosity and flow, carrying various cell materials with it. The activity can be stimulated by sunlight or heat. In March 1972, NASA and the National Science Teachers Association selected 25 experiment proposals for flight on Skylab. Science advisors from the Marshall Space Flight Center aided and assisted the students in developing the proposals for flight on Skylab.

  6. Bioethics and Climate Change: A Response to Macpherson and Valles. (United States)

    Resnik, David B


    Two articles published in Bioethics recently have explored the ways that bioethics can contribute to the climate change debate. Cheryl Cox Macpherson argues that bioethicists can play an important role in the climate change debate by helping the public to better understand the values at stake and the trade-offs that must be made in individual and social choices, and Sean Valles claims that bioethicists can contribute to the debate by framing the issues in terms of the public health impacts of climate change. While Macpherson and Valles make valid points concerning a potential role for bioethics in the climate change debate, it is important to recognize that much more than ethical analysis and reflection will be needed to significantly impact public attitudes and government policies.

  7. 聚焦尼古拉%Spotighto Nicola

    Institute of Scientific and Technical Information of China (English)


    @@ 由Cheryl Tweedy、Kimberley Walsh、Nadine Coyle、Nicola Roberts 、Sarah Harding 五位才艺美少女所组成的"女孩乐团",在2003年各界瞩目下推出首张专辑"Sound Of The Underground" 中入全英专辑榜亚军,同时推出的单曲"No Good Advice"也入座单曲榜亚军位置.别以为漂亮的美眉就只会搔首弄姿跳着既定舞步, "女孩乐团"要让你耳目一新!

  8. Luminescence and photosynthesis of marine phytoplankton - a brief presentation of new results

    Directory of Open Access Journals (Sweden)

    Bogdan Wo¼niak


    Full Text Available This volume contains a set of eight papers presenting the results of the latest research into the interaction of light with marine phytoplankton by teams from the Marine Physics Department at the IO PAS in Sopot, and the Department of Environmental Physics at the Pedagogical University of Slupsk. These results were presented at the 'Second Workshop on Luminescence and Photosynthesis of Marine Phytoplankton' (Sopot-Paraszyno, 11-15 October 1999 sponsored by the Polish State Committee for Scientific Research. This introductory article discusses the most important assumptions and objectives of the research, and outlines the latest results. These are subsequently discussed in detail in the following papers: (1 Majchrowski & Ostrowska, Influence of photo- and chromatic acclimation on pigment composition in the sea, (2 Wozniak et al., Model of the 'in vivo' spectral absorption of algal pigments. Part 1. Mathematical apparatus, (3 Majchrowski et al., Model of the 'in vivo'spectral absorption of algal pigments. Part 2. Practical applications of the model, (4 Ostrowska et al., Variability of the specific fluorescence of chlorophyll in the ocean. Part 1. Theory of classical 'in situ' chlorophyll fluorometry, (5 Ostrowska et al., Variability of the specific fluorescence of chlorophyll in the ocean. Part 2. Fluorometric method of chlorophyll a determination, (6 Ficek et al., Influence of non-photosynthetic pigments on the measured quantum yield of photosynthesis, (7 Ficek et al., Variability of the portion of functional PS2 reaction centres in the light of a fluorometric study. For the reader's convenience, we append a list of the symbols denoting the physical quantities used in the texts. The nomenclature and denotations are in line with the conventions employed in the subject literature.

  9. Bioethics and the Framing of Climate Change's Health Risks. (United States)

    Valles, Sean A


    Cheryl Cox MacPherson recently argued, in an article for this journal, that 'Climate Change is a Bioethics Problem'. This article elaborates on that position, particularly highlighting bioethicists' potential ability to help reframe the current climate change discourse to give more attention to its health risks. This reframing process is especially important because of the looming problem of climate change skepticism. Recent empirical evidence from science framing experiments indicates that the public reacts especially positively to climate change messages framed in public health terms, and bioethicists are particularly well positioned to contribute their expertise to the process of carefully developing and communicating such messages. Additionally, as climate framing research and practice continue, it will be important for bioethicists to contribute to the creation of that project's nascent ethical standards. The discourse surrounding antibiotic resistance is posited as an example that can lend insight into how communicating a public health-framed message, including the participation of bioethicists, can help to override public skepticism about the findings of politically contentious scientific fields. © 2014 John Wiley & Sons Ltd.

  10. The efficacy and safety of adalimumab in ocular inflammatory disease

    Directory of Open Access Journals (Sweden)

    Arcinue CA


    Full Text Available Cheryl A Arcinue,1,2 Khayyam Durrani,1–3 Pichaporn Artornsombudh,1,2 Alaa Radwan,1,2 Ravi Parikh,1,2 Ana M Suelves,1,2 Sana S Siddique,1,2 Ian Chang,1,2 Janine M Preble,1,2 Charles Stephen Foster1–3 1Massachusetts Eye Research and Surgery Institution, 2Ocular Immunology and Uveitis Foundation, Cambridge, 3Department of Ophthalmology, Harvard Medical School, Boston, MA, USA Objective: To evaluate the efficacy and safety of adalimumab in the management of ocular inflammation at our institution. Methods: We performed a review of all patients with active ocular inflammation treated with adalimumab at our institution. Results: Seventy eyes of 49 patients were reviewed. The mean duration of follow-up was 19.6 months. Therapy with an average of 2.1 immunomodulatory agents had been attempted prior to adalimumab therapy. At 1-year follow-up, adalimumab was effective in achieving quiescence in 33 eyes (47%. The most common side effects were injection-site reactions, arthralgias, and nausea, occurring in two patients each. Adalimumab was discontinued due to side effects in 12 patients. Conclusion: These results suggest that adalimumab is an effective and safe therapeutic modality in ocular inflammation. Keywords: uveitis, biologic response modifier, TNF-α, adverse effects, therapeutic outcomes, scleritis, peripheral ulcerative keratitis

  11. ’n Narratief vir kerk-wees vandag

    Directory of Open Access Journals (Sweden)

    J. Christo van der Merwe


    Full Text Available A narrative of church life today. We live in a time when survival seems to be the biggest concern of most mainline congregations and denominations. How can the church possibly survive? This is a question that is asked in almost every corner of the institution. Since the 1960s, numerous books and articles have been published, trying to get a handle on why the mainline churches are in decline. Whatever the cause may be, decline is causing great fear and anxiety in the mainline churches. In an effort to answer the underlying question: ‘What shall we do to turn the situation around?’, some churches are simply trying to ‘market’ themselves and their message. Others try to ’do’ church differently. Some try to rediscover the purpose of the church, et cetera. Cheryl Peterson argues that churches are, in fact, facing an ecclesial crisis, that is much more than a crisis of declining numbers and membership. There is a deeper and more basic issue that must be explored, one that has to do with the church’s theological identity, and that is: what it means to be church? This article is about the question: Who is the church? And it answers the question on the basis of Peterson’s thesis by means of a narrative of the church that commences with the Spirit.

  12. International Coference Calendar of 2001

    Institute of Scientific and Technical Information of China (English)


    221st American Chemical Society National Meeting, San Diego, California April l-5, 2001 Contact: Department of Meetings, American Chemical Society, 1155-16th St., NW, Washington DC 20036, Tel: (202)872-4396,(202) 872-6128 Email: Materials Research Society, San Francisco, Chifornia Contact: Materials Research Society, 506 Keystone Dr. Warrendale PA 15086-7573. Tel: (724) 779-3003, Fax: (724) 779-8313 Email: Homepage: www. mrs. org. 222nd American Chemical Society National Meeting, Chicago, lllinois August 26-30, 2001 Contact: Department of Meetings, American Chemical Society, 1155-16th St., NW, Washington, DC 20036. Tel: (202) 8724396, (202) 8726128 Email: International Symposium on High Performance Liquid Phase Separation, Kyoto, Japan September 11-14, 2001 Contact: Nobuo Tanaka, Kyoto Institute of Technology, Kyoto, Japan. Email: 2001 Fine Powder Processing, State College, Pennsylvania October 1-3, 2001 Contact: Cheryl Knobloch, Particle Materials Center, The Pennsylvania State University, 225 Materials Research Laboratory, University Park, PA 168024801. Tel: (814) 8636156, Fax: (814) 8639704 Email:, conferenceinfo@cde.

  13. Predictores de depresión posparto en puerperas atendidas en la ese municipal. Villavicencio. 2014

    Directory of Open Access Journals (Sweden)

    Luz Myriam Tobón-Borrero


    Full Text Available El presente estudio tuvo como objetivo determinar los predictores de la depresión posparto. Se realizaron visitas domiciliares a las maternas que asistieron a la cita de puerperio en las IPS´s de la ESE Municipal de Villavicencio durante los meses de febrero y marzo de 2014. Diseño descriptivo de corte transversal, con enfoque cuantitativo. La muestra no probabilística de 34 mujeres puérperas atendidas en la IPS La Esperanza, Porfía, Morichal y Popular de la E.S.E Municipal de Villavicencio; Instrumento fue la Escala de Detección Sistemática de Depresión Posparto (PDSS de Cheryl Tatano y colaboradores. Resultados. En la evaluación de la probabilidad de presencia de síntomas agrupados en dimensiones y su asociación con DPSS los hallazgos en la muestra estudio (n=32, determinaron significancia en tres de las siete: labilidad emocional, culpa/vergüenza y ansiedad/inseguridad. Se partió desde una perspectiva bilateral, esto es, desde la hipótesis alternativa que consistió en asumir que existen diferencias en la prevalencia de la DPSS según la presencia de las diferentes dimensiones, grupos de síntomas, que presentaban las usuarias

  14. Establishing a framework for building multidisciplinary programs

    Directory of Open Access Journals (Sweden)

    Meguid C


    Full Text Available Cheryl Meguid,1 Carrie E Ryan,2 Barish H Edil,1 Richard D Schulick,1 Csaba Gajdos,1 Megan Boniface,1 Tracey E Schefter,3 W Thomas Purcell,4 Martin McCarter1 1Department of Surgery, Division of GI, Tumor, and Endocrine Surgery, Section of Surgical Oncology, University of Colorado Hospital, Aurora, CO, 2Morsani College of Medicine, University of South Florida, Tampa, FL, 3Department of Radiation Oncology, University of Colorado Denver, Denver, CO, 4Department of Medicine, Division of Medical Oncology, University of Colorado Hospital, Aurora, CO, USA Abstract: While most providers support the concept of a multidisciplinary approach to patient care, challenges exist to the implementation of successful multidisciplinary clinical programs. As patients become more knowledgeable about their disease through research on the Internet, they seek hospital programs that offer multidisciplinary care. At the University of Colorado Hospital, we utilize a formal multidisciplinary approach across a variety of clinical settings, which has been beneficial to patients, providers, and the hospital. We present a reproducible framework to be used as a guide to develop a successful multidisciplinary program. Keywords: multidisciplinary clinic, patient centered, tumor board

  15. Reflections on the journey: six short stories. (United States)

    Haynie, Sharon L; Hinkle, Amber S; Jones, Nancy L; Martin, Cheryl A; Olsiewski, Paula J; Roberts, Mary F


    One of the goals of the 2011 International Year of Chemistry is to celebrate the contributions of women to science. A question that has been frequently asked in this regard is... Why is it necessary to highlight women in the "age of equality"? The reasons are varied but the facts are that many women scientists worked in obscurity throughout the 19th and even well into the 20th century, sometimes publishing anonymously to be heard. This celebration of Women in Science is one way to recognize both the resiliency and passion of these women. As part of this celebration, Chemistry Central Journal's Thematic Series of "Women in Chemistry" includes this article describing the path several women took as they pursued chemistry careers spanning the latter part of the 20th century and into the early 21st century. Sharon Haynie, Nancy Jones, Cheryl Martin, Paula Olsiewski, Mary Roberts and Amber Hinkle each have unique story of their personal journey from childhood to adulthood. As you read these stories, listen generously, and feel free to share your own stories, comments and thoughts.

  16. Becoming-Ariel: Viewing Julie Taymor’s The Tempest through an Ecocritical Lens

    Directory of Open Access Journals (Sweden)

    Clare Sibley-Esposito


    Full Text Available The burgeoning field of ecocriticism takes what Cheryll Glotfelty has referred to as an “earth-centered approach” to cultural productions, with ecocritics sharing a concern with the interconnectedness of human and non-human spheres. This article presents a brief overview of some ecocritical readings of The Tempest, before interpreting Julie Taymor’s cinematographic adaptation in the light of such considerations. Taymor attributes a rather unproblematic power of manipulation of the natural world to her Prospera, yet some of her directorial choices, operating within the specificity of the film medium, tend nonetheless to highlight certain ecocritically-relevant dimensions of Shakespeare’s text. By viewing the film through an ecocritical lens, whilst borrowing terminology from Gilles Deleuze and Félix Guattari, the figure of Ariel can be seen as operating on a “molecular plane” of ontological interconnectivity, in contrast to the “molar mode” of binary oppositions inherent in Prospera’s desire to dominate natural forces.

  17. Parent–Child Interaction Therapy: current perspectives

    Directory of Open Access Journals (Sweden)

    Lieneman CC


    Full Text Available Corey C Lieneman, Laurel A Brabson, April Highlander, Nancy M Wallace, Cheryl B McNeil Department of Psychology, West Virginia University, Morgantown, WV, USA Abstract: Parent–Child Interaction Therapy (PCIT is an empirically supported intervention originally developed to treat disruptive behavior problems in children between the ages of 2 and 7 years. Since its creation over 40 years ago, PCIT has been studied internationally with various populations and has been found to be an effective intervention for numerous behavioral and emotional issues. This article summarizes progress in the PCIT literature over the past decade (2006–2017 and outlines future directions for this important work. Recent PCIT research related to treatment effectiveness, treatment components, adaptations for specific populations (age groups, cultural groups, military families, individuals diagnosed with specific disorders, trauma survivors, and the hearing-impaired, format changes (group and home-based, teacher–child interaction training (TCIT, intensive PCIT (I-PCIT, treatment as prevention (for externalizing problems, child maltreatment, and developmental delays, and implementation are discussed. Keywords: PCIT, adaptations, implementation, effectiveness

  18. Estrogens of multiple classes and their role in mental health disease mechanisms

    Directory of Open Access Journals (Sweden)

    Cheryl S Watson


    Full Text Available Cheryl S Watson1, Rebecca A Alyea1, Kathryn A Cunningham2, Yow-Jiun Jeng11Department of Biochemistry and Molecular Biology, 2Department of Pharmacology and Toxicology, Univ of Texas Medical Branch, Galveston, TX, USAAbstract: Gender and sex hormones can influence a variety of mental health states, including mood, cognitive development and function, and vulnerability to neurodegenerative diseases and brain damage. Functions of neuronal cells may be altered by estrogens depending upon the availability of different physiological estrogenic ligands; these ligands and their effects vary with life stages, the genetic or postgenetic regulation of receptor levels in specific tissues, or the intercession of competing nonphysiological ligands (either intentional or unintentional, beneficial to health or not. Here we review evidence for how different estrogens (physiological and environmental/dietary, acting via different estrogen receptor subtypes residing in alternative subcellular locations, influence brain functions and behavior. We also discuss the families of receptors and transporters for monoamine neurotransmitters and how they may interact with the estrogenic signaling pathways.Keywords: estrogen receptor α, estrogen receptor β, GPR30, GPER, xenoestrogens, phytoestrogens, transporters, brain function, neurotransmitter receptors

  19. Mi'kmaq Night Sky Stories; Patterns of Interconnectiveness, Vitality and Nourishment (United States)

    Harris, P.; Bartlett, C.; Marshall, M.; Marshall, A.


    This article shares some of the experiences of an integrative science team based at Cape Breton University, Canada. Integrative science is defined as "bringing together Indigenous and Western scientific knowledge and ways of knowing" and the team includes Mi'kmaq Elders and educators, Cheryl Bartlett and her Research Associates. Together we worked to rekindle the Mi'kmaq Sky Story, Muin and the Seven Hunters, to produce a DVD of the story as well as a children's book, and then to share it with people throughout Canada and the world. We offer insights into the manner in which night sky stories engender interconnectiveness and interdependability through their cultural, scientific and ecological teachings and so help to revitalise the culture and the individual by feeding all aspects of the human experience (spiritual, emotional, physical and cognitional). We explore the concept of storywork, with emphasis on the relationship between storyteller and listener as a story is told, as well as considering the multi-layered aspect of Indigenous stories.

  20. Critical ethnography: An under-used research methodology in neuroscience nursing. (United States)

    Ross, Cheryl; Rogers, Cath; Duff, Diane


    Critical ethnography is a qualitative research method that endeavours to explore and understand dominant discourses that are seen as being the 'right' way to think, see, talk about or enact a particular 'action' or situation in society and recommend ways to re-dress social power inequities. In health care, vulnerable populations, including many individuals who have experienced neurological illnesses or injuries that leave them susceptible to the influence of others, would be suitable groups for study using critical ethnography methodology. Critical ethnography has also been used to study workplace culture. While ethnography has been effectively used to underpin other phenomena of interest to neuroscience nurses, only one example of the use of critical ethnography exists in the published literature related to neuroscience nursing. In our "Research Corner" in this issue of the Canadian Journal of Neuroscience Nursing (CJNN) our guest editors, Dr. Cheryl Ross and Dr. Cath Rogers will briefly highlight the origins of qualitative research, ethnography, and critical ethnography and describe how they are used and, as the third author, I will discuss the relevance of critical ethnography findings for neuroscience nurses.

  1. Canadian Rheumatology Association Meeting, Fairmont Chateau Lake Louise, Lake Louise, Alberta, Canada, February 17-20, 2016. (United States)

    Silverman, Earl D


    The 71st Annual Meeting of The Canadian Rheumatology Association (CRA) was held at the Fairmont Chateau Lake Louise, Lake Louise, Alberta, Canada, February 17-20, 2016. The program consisted of presentations covering original research, symposia, awards, and lectures. Highlights of the meeting include the following 2016 Award Winners: Distinguished Rheumatologist, Ronald Laxer; Distinguished Investigator, Proton Rahman; Teacher-Educator, Lori Albert; Young Investigator, Nigil Haroon; Best Abstract on Basic Science Research by a Trainee, Liam O'Neil; Best Abstract on Research by a Rheumatology Resident, Valérie Leclair; Best Abstract by a Medical Student, Matthew Jessome; Best Abstract by a Post-Graduate Resident, Hyein Kim; CRA/Arthritis Research Foundation (ARF) Best Epidemiology/Health Services Research Award, Cheryl Barnabe; Summer Studentship Mentor Award, Ines Colmegna; CRA/ARF Best Paediatric Research Award, Lily Lim; CRA/ARF Best Clinical Research Award, Zahi Touma; CRA/ARF Best Basic Science Research Award, Nigil Haroon; Best Abstract on SLE Research by a Trainee - Ian Watson Award, Stephanie Nantes.

  2. Political Ecology in Gabriel Garcia Marquez's One Hundred Years of Solitude

    Directory of Open Access Journals (Sweden)

    Eman Mohammed ElSherief


    Full Text Available The roots of ecology prolong profoundly within earlier phases of history, when the naturalistic fabric was first evinced.  Bringing out his On the Origin of Species in 1859, Darwin not merely engendered a biological culmination but also heralded the revolutionary critical canon of naturalism that was virtually a stone thrown in the vast stagnant lake of traditional literature. Via the naturalistic lens, the whole bulk of man’s behavioral attributes are being expounded in terms of milieu and heredity. The mid-1990s witnessed the publication of The Environmental Imagination by Lawrence Buell in 1995, and The Ecocriticism Reader edited by Cheryll Gloffelty and Harold Fromm in 1996, which palpably underpinned ecocriticism as revolving around the inextricable liaison between literature and the physical environment. The political ecology term was coined to further scrutinize relations among people that pertain to nature. The present paper is an endeavor to pursue the ecological tenor of Gabriel Garcia Marquez’s landmark novel, One Hundred Years of Solitude, and how it was admirably exploited to address precarious postcolonial issues. Keywords: Political ecology, Marquez, naturalism, ecocriticism, post-colonialism.

  3. Del Patrimonio al Terrorismo. Regular el Turismo en una Época de Incertidumbre.

    Directory of Open Access Journals (Sweden)

    Maximiliano E Korstanje


    Full Text Available Aun cuando la investigación aplicada en turismo conciba al terrorismo como la peor amenaza de este siglo, algunos autores han sostenido que existe una relación entre turismo y terrorismo. En efecto, estos trabajos apuntan a pensar el terrorismo como una resultante del nivel de vida económico, de la pobreza o como un mecanismo nivelador de la frustración social. Pero lejos de llegar a una explicación univoca, no demoraron en aparecer otras voces para las cuales el fenómeno no sería otra cosa que el choque cultural entre dos tipos o estilos de vida. Cualquiera sea el caso, pocos se han detenido a estudiar el rol que juega el andamiaje jurídico y sobre todo la ley, en el proceso de violencia que despierta el terrorismo. En vistas de ello, Del Patrimonio al Terrorismo, trabajo de Brian and Cheryl Simpson, presenta una nueva y provocativa versión que ayuda al lector a expandir las fronteras cognitivas respecto a este tema de indudable actualidad. 

  4. Discharge destination from an acute care for the elderly (ACE unit

    Directory of Open Access Journals (Sweden)

    Luis F Amador


    Full Text Available Luis F Amador1,2, Carlos A Reyes-Ortiz1,2, Diana Reed 3, Cheryl Lehman2,41Department of Internal Medicine, 2Sealy Center on Aging, 3Department Care Management, 4Department of Nursing, University of Texas Medical Branch at Galveston, TX, USA Abstract: Older adults age 65 and over account for a disproportional number of hospital stays and discharges compared to other age groups. The objective of this paper is to describe placement and characteristics of older patients discharged from an acute care for the elderly (ACE unit. The study sample consists of 1,351 men and women aged 65 years or older that were discharged from the ACE Unit during a 12-month period. The mean number of discharges per month was 109.2 ± 28.4. Most of the subjects were discharged home or home with home health 841, 62.3%. The oldest elderly and patients who had been admitted from long term care institutions or from skilled nursing facilities to the ACE unit were less likely to return to home.Keywords: hospitalization, geriatric, discharge disposition

  5. Titanium dioxide nanoparticles enhance production of superoxide anion and alter the antioxidant system in human osteoblast cells

    Directory of Open Access Journals (Sweden)

    Niska K


    Full Text Available Karolina Niska,1 Katarzyna Pyszka,1 Cecylia Tukaj,2 Michal Wozniak,1 Marek Witold Radomski,3–5 Iwona Inkielewicz-Stepniak1 1Department of Medical Chemistry, 2Department of Electron Microscopy, Medical University of Gdansk, Gdansk, Poland; 3School of Pharmacy and Pharmaceutical Sciences, Trinity Biomedical Sciences Institute, The University of Dublin Trinity College, Dublin, Ireland; 4Kardio-Med Silesia, 5Silesian Medical University, Zabrze, Poland Abstract: Titanium dioxide (TiO2 nanoparticles (NPs are manufactured worldwide for a variety of engineering and bioengineering applications. TiO2NPs are frequently used as a material for orthopedic implants. However, to the best of our knowledge, the biocompatibility of TiO2NPs and their effects on osteoblast cells, which are responsible for the growth and remodeling of the human skeleton, have not been thoroughly investigated. In the research reported here, we studied the effects of exposing hFOB 1.19 human osteoblast cells to TiO2NPs (5–15 nm for 24 and 48 hours. Cell viability, alkaline phosphatase (ALP activity, cellular uptake of NPs, cell morphology, superoxide anion (O2•- generation, superoxide dismutase (SOD activity and protein level, sirtuin 3 (SIR3 protein level, correlation between manganese (Mn SOD and SIR, total antioxidant capacity, and malondialdehyde were measured following exposure of hFOB 1.19 cells to TiO2NPs. Exposure of hFOB 1.19 cells to TiO2NPs resulted in: (1 cellular uptake of NPs; (2 increased cytotoxicity and cell death in a time- and concentration-dependent manner; (3 ultrastructure changes; (4 decreased SOD and ALP activity; (5 decreased protein levels of SOD1, SOD2, and SIR3; (6 decreased total antioxidant capacity; (7 increased O2•- generation; and (8 enhanced lipid peroxidation (malondialdehyde level. The linear relationship between the protein level of MnSOD and SIR3 and between O2•- content and SIR3 protein level was observed. Importantly, the cytotoxic

  6. Summary of SMIRT20 Preconference Topical Workshop – Identifying Structural Issues in Advanced Reactors

    Energy Technology Data Exchange (ETDEWEB)

    William Richins; Stephen Novascone; Cheryl O' Brien


    Summary of SMIRT20 Preconference Topical Workshop – Identifying Structural Issues in Advanced Reactors William Richins1, Stephen Novascone1, and Cheryl O’Brien1 1Idaho National Laboratory, US Dept. of Energy, Idaho Falls, Idaho, USA, e-mail: The Idaho National Laboratory (INL, USA) and IASMiRT sponsored an international forum Nov 5-6, 2008 in Porvoo, Finland for nuclear industry, academic, and regulatory representatives to identify structural issues in current and future advanced reactor design, especially for extreme conditions and external threats. The purpose of this Topical Workshop was to articulate research, engineering, and regulatory Code development needs. The topics addressed by the Workshop were selected to address critical industry needs specific to advanced reactor structures that have long lead times and can be the subject of future SMiRT technical sessions. The topics were; 1) structural/materials needs for extreme conditions and external threats in contemporary (Gen. III) and future (Gen. IV and NGNP) advanced reactors and 2) calibrating simulation software and methods that address topic 1 The workshop discussions and research needs identified are presented. The Workshop successfully produced interactive discussion on the two topics resulting in a list of research and technology needs. It is recommended that IASMiRT communicate the results of the discussion to industry and researchers to encourage new ideas and projects. In addition, opportunities exist to retrieve research reports and information that currently exists, and encourage more international cooperation and collaboration. It is recommended that IASMiRT continue with an off-year workshop series on select topics.

  7. Refinement of the Long-Term Conditions Questionnaire (LTCQ: patient and expert stakeholder opinion

    Directory of Open Access Journals (Sweden)

    Kelly L


    Full Text Available Laura Kelly,1 Caroline M Potter,1 Cheryl Hunter,2 Elizabeth Gibbons,1 Ray Fitzpatrick,1 Crispin Jenkinson,1 Michele Peters1 1Health Services Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, 2Academic Unit of Primary Care, Leeds Institute of Health Sciences, University of Leeds, Leeds, UK Purpose: It is a key UK government priority to assess and improve outcomes in people with long-term conditions (LTCs. We are developing a new patient-reported outcome measure, the Long-Term Conditions Questionnaire (LTCQ, for use among people with single or multiple LTCs. This study aimed to refine candidate LTCQ items that had previously been informed through literature reviews, interviews with professional stakeholders, and interviews with people with LTCs. Materials and methods: Cognitive interviews (n=32 with people living with LTCs and consultations with professional stakeholders (n=13 and public representatives (n=5 were conducted to assess the suitability of 23 candidate items. Items were tested for content and comprehensibility and underwent a translatability assessment. Results: Four rounds of revisions took place, due to amendments to item structure, improvements to item clarity, item duplication, and recommendations for future translations. Twenty items were confirmed as relevant to living with LTCs and understandable to patients and professionals. Conclusion: This study supports the content validity of the LTCQ items among people with LTCs and professional stakeholders. The final items are suitable to enter the next stage of psychometric refinement. Keywords: long-term conditions, chronic conditions, cognitive debrief interviews, patient-reported

  8. Evaluating an undergraduate interprofessional simulation-based educational module: communication, teamwork, and confidence performing cardiac resuscitation skills

    Directory of Open Access Journals (Sweden)

    Marian Luctkar-Flude


    Full Text Available Marian Luctkar-Flude1, Cynthia Baker1, Cheryl Pulling1, Robert McGraw2, Damon Dagnone2, Jennifer Medves1, Carly Turner-Kelly11School of Nursing, Queen’s University, Kingston, Ontario, Canada; 2School of Medicine, Queen’s University, Kingston, Ontario, CanadaPurpose: Interprofessional (IP collaboration during cardiac resuscitation is essential and contributes to patient wellbeing. The purpose of this study is to evaluate an innovative simulation-based IP educational module for undergraduate nursing and medical students on cardiac resuscitation skills.Methods: Nursing and medical trainees participated in a new cardiac resuscitation curriculum involving a 2-hour IP foundational cardiac resuscitation skills lab, followed by three 2-hour IP simulation sessions. Control group participants attended the existing two 2-hour IP simulation sessions. Study respondents (N = 71 completed a survey regarding their confidence performing cardiac resuscitation skills and their perceptions of IP collaboration.Results: Despite a consistent positive trend, only one out of 17 quantitative survey items were significantly improved for learners in the new curriculum. They were more likely to report feeling confident managing the airway during cardiac resuscitation (P = 0.001. Overall, quantitative results suggest that senior nursing and medical students were comfortable with IP communication and teamwork and confident with cardiac resuscitation skills. There were no significant differences between nursing students’ and medical students’ results. Through qualitative feedback, participants reported feeling comfortable learning with students from other professions and found value in the IP simulation sessions.Conclusion: Results from this study will inform ongoing restructuring of the IP cardiac resuscitation skills simulation module as defined by the action research process. Specific improvements that are suggested by these findings include strengthening the team

  9. A case of mistaken identity: alcohol withdrawal, schizophrenia, or central pontine myelinolysis?

    Directory of Open Access Journals (Sweden)

    Schneider P


    Full Text Available Paul Schneider1, Vicki A Nejtek2,3, Cheryl Hurd2,31Green Oaks Behavioral Health Care Services, Dallas, 2University of North Texas Health Science Center, Fort Worth, 3John Peter Smith Health Network, Fort Worth, Texas, USAAbstract: Demyelination is a hallmark of central pontine myelinolysis (CPM. Neuropsychiatric manifestations of this condition include weakness, quadriplegia, pseudobulbar palsy, mood changes, psychosis, and cognitive disturbances. These psychiatric symptoms are also associated with schizophrenia and alcohol withdrawal. Thus, it is clinically relevant to differentiate between CPM, schizophrenia, and alcohol withdrawal as the treatment and prognostic outcomes for each diagnosis are distinct. We present a series of events that led to a misdiagnosis of a patient admitted to the medical emergency center presenting with confusion, psychomotor agitation, and delirium who was first diagnosed with schizophrenia and alcohol withdrawal by emergency medical physicians and later discovered by the psychiatric consult team to have CPM. With a thorough psychiatric evaluation, a review of the laboratory results first showing mild hyponatremia (127 mmol/L, subsequent hypernatremia (154 mmol/L, and magnetic resonance brain imaging, psychiatrists concluded that CPM was the primary diagnosis underlying the observed neuropsychopathology. This patient has mild impairments in mood, cognition, and motor skills that remain 12 months after her emergency-center admission. This case report reminds emergency clinicians that abnormal sodium metabolism can have long-term and devastating psychopathological and neurological consequences. Differentiating between CPM, schizophrenia, and alcohol withdrawal using neuroimaging techniques and preventing the risks for CPM using slow sodium correction are paramount.Keywords: MRI, alcohol, schizophrenia, central pontine myelinolysis, hyponatremia

  10. A prospective echocardiographic evaluation of pulmonary hypertension in chronic hemodialysis patients in the United States: prevalence and clinical significance

    Directory of Open Access Journals (Sweden)

    Kumudha Ramasubbu


    Full Text Available Kumudha Ramasubbu1, Anita Deswal1, Cheryl Herdejurgen2, David Aguilar1, Adaani E Frost21Section of Cardiology, Michael E DeBakey VA Medical Center and Baylor College of Medicine, Houston, Texas, USA; 2Section of Pulmonary and Critical Care Medicine, Baylor College of Medicine, Houston, Texas, USABackground: Pulmonary hypertension (PH, a disease which carries substantial morbidity and mortality, has been reported to occur in 25%–45% of dialysis patients. No prospective evaluation of the prevalence or clinical significance of PH in chronic dialysis patients in the United States (US has been undertaken.Methods: Echocardiograms were performed prospectively in chronic hemodialysis patients prior to dialysis at a single dialysis center. PH was defined as a tricuspid regurgitant jet ≥2.5 m/s and “more severe PH” as ≥3.0 m/s. Clinical outcomes recovered were all-cause hospitalizations and death at 12 months.Results: In a cohort of 90 patients, 42 patients (47% met the definition of PH. Of those, 18 patients (20% met the definition of more severe PH. At 12 months, mortality was significantly higher in patients with PH (26% compared with patients without PH (6%. All-cause hospitalizations were similar in patients with PH and without PH. Echocardiographic findings suggesting impaired left ventricular function and elevated pulmonary capillary wedge pressure were significantly associated with PH.Conclusion: This prospective cross-sectional study of a single dialysis unit suggests that PH may be present in nearly half of US dialysis patients and when present is associated with increased mortality. Echocardiographic findings demonstrate an association between elevated filling pressures, elevated pulmonary artery pressures, and higher mortality, suggesting that the PH may be secondary to diastolic dysfunction and compounded by volume overload.Keywords: renal failure, pulmonary hypertension, diastolic dysfunction

  11. Gonorrhea infection in women: prevalence, effects, screening, and management

    Directory of Open Access Journals (Sweden)

    Walker CK


    Full Text Available Cheryl K Walker, Richard L SweetWomen’s Center for Health, Department of Obstetrics and Gynecology, University of California, Davis School of Medicine, Sacramento, CA, USAAbstract: Gonorrhea is a set of clinical conditions resulting from infection with the sexually-acquired bacterial pathogen Neisseria gonorrhoeae. Acquisition may involve multiple mucosal sites in the lower female genital tract, including the urethra, cervix, Bartholin’s and Skene’s glands, as well as the anorectal canal, pharynx, and conjunctivae. It may spread to the upper genital tract, uterine tubes, abdominal cavity, and other systemic sites. Gonorrhea is the second most commonly reported sexually-transmitted infection in the US and rates are higher among women than men. Women and infants are affected disproportionately by gonorrhea, because early infection may be asymptomatic and also because extension of infection is often associated with serious sequelae. Screening is critical for infection identification and the prevention or limitation of upper genital tract spread, and horizontal and vertical transmission. Routine genital screening is recommended annually for all sexually active women at risk for infection, including women aged < 25 years and older women with one or more of the following risks: a previous gonorrhea infection, the presence of other sexually transmitted diseases, new or multiple sex partners, inconsistent condom use, commercial sex work, drug use, or human immunodeficiency virus infection with sexual activity or pregnancy. Pharyngeal gonococcal infections are common in adolescents, and direct culture screening is necessary to identify affected individuals. Nucleic acid amplification tests (NAATs are considered the standard for screening and diagnosis. Although urine NAAT testing is most commonly used, there is growing support for vaginal swabs collected by providers or patients themselves. Resistance to all antibiotics currently recommended for

  12. Optimal lipid modification: the rationale for combination therapy

    Directory of Open Access Journals (Sweden)

    James M Backes


    Full Text Available James M Backes1, Cheryl A Gibson2, Patricia A Howard31Department of Pharmacy Practice, Lipid, Atherosclerosis, Metabolic and LDL Apheresis Center, University of Kansas Medical Center, Kansas City, KS, USA; 2Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA; 3Department of Pharmacy Practice, University of Kansas School of Pharmacy, Kansas City, KS, USABackground: An emphasis on more aggressive lipid-lowering, particularly of low-density lipoprotein cholesterol, to improve patient outcomes has led to an increased use of combination lipid-lowering drugs. This strategy, while potentially beneficial, has triggered concerns regarding fears of adverse effects, harmful drug interactions, and patient nonadherence.Objective: To present key data regarding combination lipid-altering therapy including use, rationale, major trials, benefits, potential adverse effects, compliance issues, and limitations. Method: Literature was obtained from MEDLINE (1966 – June 2005 and references from selected articles.Results: A substantial body of evidence from epidemiological data and clinical trials indicates that aggressive lipid modification, especially low-density lipoprotein reduction, is associated with reduced cardiovascular events. Numerous studies utilizing various combinations of cholesterol-lowering agents including statin/fibrate, statin/niacin, statin/bile acid resin, and statin/ezetimibe have demonstrated significant changes in the lipid profile with acceptable safety. Long-term trials of combination therapy evaluating clinical outcomes or surrogate markers of cardiovascular disease, while limited, are promising.Conclusion: Combining lipid-altering agents results in additional improvements in lipoproteins and has the potential to further reduce cardiovascular events beyond that of monotherapy.Keywords: combination therapy, coronary heart disease, hypercholesterolemia, lipid-lowering, low-density lipoprotein, statins

  13. Carbidopa/levodopa/entacapone: the evidence for its place in the treatment of Parkinson’s disease

    Directory of Open Access Journals (Sweden)

    Markos Poulopoulos


    Full Text Available Markos Poulopoulos, Cheryl WatersDepartment of Neurology, Division of Movement Disorders, Columbia University Medical Center, Neurological Institute of New York, Center of Parkinson’s Disease and Other Movement Disorders, New York, NY, USAIntroduction: Parkinson’s disease (PD is a common neurodegenerative disease. In the 1960s, it was shown that the degeneration of dopamine producing neurons in the substantia nigra (SN caused the motor features of PD. Dopamine replacement with levodopa, a dopamine precursor, resulted in remarkable benefit. Yet, the intermittent administration of levodopa is a major cause of motor complications, such as “wearing-off ” of levodopa’s benefit and involuntary movements, known as dyskinesia. Therefore, agents that prolong levodopa’s half-life were employed, such as carbidopa, an aromatic amino acid decarboxylase (AADC inhibitor, and entacapone, a catechol-O-methyltransferase (COMT inhibitor. The combination product carbidopa/levodopa/entacapone (CLE was approved in 2003 for the treatment of PD patients.Aims: To assess the evidence for the place of CLE in the treatment of PD.Evidence review: CLE has a good efficacy, safety and tolerability profile, similar to that of entacapone taken separately with carbidopa/levodopa (CL. Compared to CL alone, it prolongs levodopa’s benefit, and improves the quality of life but not the motor performance in PD patients with nondebilitating “wearing-off ” or dyskinesia. However, it increases the dyskinesia rate in early PD patients, and has adverse events in advanced patients with significant motor complications. There is insufficient evidence regarding cost-effectiveness.Place in therapy: CLE is an attractive alternative for patients with nondisabling “wearing-off ” or dyskinesia taking CL with or without entacapone. It cannot be recommended for early PD patients, as it can induce more dyskinesia than CL alone, or in any patients who seem to have more adverse

  14. Multidisciplinary management for esophageal and gastric cancer

    Directory of Open Access Journals (Sweden)

    Boniface MM


    Full Text Available Megan M Boniface,1 Sachin B Wani,2 Tracey E Schefter,3 Phillip J Koo,4 Cheryl Meguid,1 Stephen Leong,5 Jeffrey B Kaplan,6 Lisa J Wingrove,7 Martin D McCarter1 1Section of Surgical Oncology, Division of GI, Tumor and Endocrine Surgery, Department of Surgery, 2Division of Gastroenterology and Hepatology, Department of Therapeutic and Interventional Endoscopy, 3Department of Radiation Oncology, 4Division of Radiology-Nuclear Medicine, Department of Radiology, 5Division of Medical Oncology, 6Department of Pathology, University of Colorado Denver, 7Department of Food and Nutrition Services, University of Colorado Hospital Cancer Center, Aurora, CO, USA Abstract: The management of esophageal and gastric cancer is complex and involves multiple specialists in an effort to optimize patient outcomes. Utilizing a multidisciplinary team approach starting from the initial staging evaluation ensures that all members are in agreement with the plan of care. Treatment selection for esophageal and gastric cancer often involves a combination of chemotherapy, radiation, surgery, and palliative interventions (endoscopic and surgical, and direct communication between specialists in these fields is needed to ensure appropriate clinical decision making. At the University of Colorado, the Esophageal and Gastric Multidisciplinary Clinic was created to bring together all experts involved in treating these diseases at a weekly conference in order to provide patients with coordinated, individualized, and patient-centered care. This review details the essential elements and benefits of building a multidisciplinary program focused on treating esophageal and gastric cancer patients. Keywords: tumor board, upper gastrointestinal malignancies, patient centered

  15. Non-Target Analyses of organic compounds in ice cores using HPLC-ESI-UHRMS (United States)

    Zuth, Christoph; Müller-Tautges, Christina; Eichler, Anja; Schwikowski, Margit; Hoffmann, Thorsten


    mass spectrometry were applied to the results of the non-target analysis. By various classifications in Van Krevelen plots[2], amino acids and degradation products of proteins as well as degradation products of lignins have been determined as the main components of the ice core. Furthermore, the majority of WSOC molecular formulas identified in this non-target analysis had molar H/C and O/C ratios similar to mono- and di-carboxylic acids and SOAs[3]. Studies of the carbon oxidation state as a metric for describing the chemistry of atmospheric organic aerosol showed that a majority of the elemental formulas can be associated with the combustion of biomass as a major source of the WSOC[4]. References: [1] Grannas et al., J. Geophys Res.,2006, 111 [2] Sleighter, RL, Hatcher, PG, J. Mass Spectrom., 2007, 42, 559-574 [3] Wozniak et al., Atmos. Chem. Phys., 2008, 8, 5099-5111 [4] Kroll et al., Nature Chemistry, 2011, 3, 133-139

  16. Environmental protection congress M-V. Use of regenerative energy sources and hydrogen technology 2010. Proceedings; Klimaschutzkongress M-V. Nutzung regenerativer Energiequellen und Wasserstofftechnik 2010. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    Luschtinetz, Thomas; Lehmann, Jochen (eds.)


    -Hydrogen-Biomass-The hybrid power plant of ENERTRAG AG (Andreas Miege); (19) The First in Poland demonstrative ORC power plant of low power output (Wladyslaw A. Stachel); (20) LED - Light in the public room (Thomas Roehmhild); (21) European prospects on shale gas (Stefan Juergen Saatmann); (21) Is hydrogen dangerous? (Ulrich Schmidtchen); (22) Ecovision Usedom - Geothermal district heating for the resorts (Sven-Uwe Schulz); (23) Conditions for a full supply with renewable energies (Gerd Stadermann); (24) Solar cells of the third generation on the basis of silicon nanostructures (Berg Stegemann); (25) Platinum-free catalysts for the hydrogen / hydrogen peroxide - fuel cell (Anette-E. Surkus); (26) The fuel cell in Germany: Future or utopia? (Guillem Taenzer); (27) Industrial waste heat - A potential investigation for Germany (Guillem Taenzer); (28) Solar-thermal substitution of electric power for air conditioning and providing drinking water - A cooperation between Ecuador and Stralsund (Jaime Vasquez); (29) Hydrogen and its technologies - The Exergetisation through hydrogen technologies makes more technical work from energy (Carl-Jochen Winter); (30) Analysis / diagnosis of mistakes in the construction and operation of photovoltaic plants and their evaluation (Klaus Wozniak); (31) Generation of hydrogen for a decentralized energy supply (Claus Wuerfel); (32) Biomass as an operating material for ships (Wojciech Zenczak).

  17. The Long-Term Conditions Questionnaire: conceptual framework and item development

    Directory of Open Access Journals (Sweden)

    Peters M


    Full Text Available Michele Peters,1 Caroline M Potter,1 Laura Kelly,1 Cheryl Hunter,1 Elizabeth Gibbons,1 Crispin Jenkinson,1 Angela Coulter,1 Julien Forder,2 Ann-Marie Towers,2 Christine A’Court,3,4 Ray Fitzpatrick1 1Health Services Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, 2Personal Social Services Research Unit, University of Kent, Canterbury, 3Nuffield Department of Primary Health Care Sciences, University of Oxford, Oxford, 4Broadshires Health Centre, Carterton, UK Purpose: To identify the main issues of importance when living with long-term conditions to refine a conceptual framework for informing the item development of a patient-reported outcome measure for long-term conditions.Materials and methods: Semi-structured qualitative interviews (n=48 were conducted with people living with at least one long-term condition. Participants were recruited through primary care. The interviews were transcribed verbatim and analyzed by thematic analysis. The analysis served to refine the conceptual framework, based on reviews of the literature and stakeholder consultations, for developing candidate items for a new measure for long-term conditions.Results: Three main organizing concepts were identified: impact of long-term conditions, experience of services and support, and self-care. The findings helped to refine a conceptual framework, leading to the development of 23 items that represent issues of importance in long-term conditions. The 23 candidate items formed the first draft of the measure, currently named the Long-Term Conditions Questionnaire.Conclusion: The aim of this study was to refine the conceptual framework and develop items for a patient-reported outcome measure for long-term conditions, including single and multiple morbidities and physical and mental health conditions. Qualitative interviews identified the key themes for assessing outcomes in long-term conditions, and these underpinned the development of the

  18. Economic analysis of empiric versus diagnostic-driven strategies for immunocompromised patients with suspected fungal infections in the People's Republic of China

    Directory of Open Access Journals (Sweden)

    Mao NY


    Full Text Available Ningying Mao,1 Beth Lesher,2 Qifa Liu,3 Lei Qin,2 Yixi Chen,4 Xin Gao,2 Stephanie R Earnshaw,5 Cheryl L McDade,5 Claudie Charbonneau,61School of International Pharmaceutical Business, China Pharmaceutical University, Nanjing, People's Republic of China; 2Pharmerit International, Bethesda, MD, USA; 3Hematology Department, Nanfang Hospital, Southern Medical University, Guangzhou, 4Pfizer Investment Co. Ltd., Beijing, People's Republic of China; 5RTI Health Solutions, Research Triangle Park, NC, USA; 6Pfizer International Operations, Paris, France Abstract: Invasive fungal infections (IFIs require rapid diagnosis and treatment. A decision-analytic model was used to estimate total costs and survival associated with a diagnostic-driven (DD or an empiric treatment approach in neutropenic patients with hematological malignancies receiving chemotherapy or autologous/allogeneic stem cell transplants in Shanghai, Beijing, Chengdu, and Guangzhou, the People's Republic of China. Treatment initiation for the empiric approach occurred after clinical suspicion of an IFI; treatment initiation for the DD approach occurred after clinical suspicion and a positive IFI diagnostic test result. Model inputs were obtained from the literature; treatment patterns and resource use were based on clinical opinion. Total costs were lower for the DD versus the empiric approach in Shanghai (¥3,232 vs ¥4,331, Beijing (¥3,894 vs ¥4,864, Chengdu, (¥4,632 vs ¥5,795, and Guangzhou (¥8,489 vs ¥9,795. Antifungal administration was lower using the DD (5.7% than empiric (9.8% approach, with similar survival rates. Results from one-way and probabilistic sensitivity analyses were most sensitive to changes in diagnostic test sensitivity and IFI incidence; the DD approach dominated the empiric approach in 88% of scenarios. These results suggest that a DD compared to an empiric treatment approach in the People’s Republic of China may be cost saving, with similar overall survival

  19. Priorities in the primary care of persons experiencing homelessness: convergence and divergence in the views of patients and provider/experts

    Directory of Open Access Journals (Sweden)

    Steward J


    Full Text Available Jocelyn Steward,1 Cheryl L Holt,2 David E Pollio,3 Erika L Austin,4,5 Nancy Johnson,4 Adam J Gordon,6,7 Stefan G Kertesz4,81Department of Health Care Management, Clayton State University, Morrow, GA, 2Department of Psychology, University of Maryland, College Park, MD, 3Department of Social Work, University of Alabama at Birmingham, 4Birmingham VA Medical Center, 5Department of Biostatistics, University of Alabama at Birmingham School of Public Health, Birmingham, AL, 6VA Pittsburgh Health Care System, 7University of Pittsburgh School of Medicine, Pittsburgh, PA, 8Department of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USAPurpose: Homeless individuals face unique challenges in health care. Several US initiatives seeking to advance patient-centered primary care for homeless persons are more likely to succeed if they incorporate the priorities of the patients they are to serve. However, there has been no prior research to elicit their priorities in primary care. This study sought to identify aspects of primary care important to persons familiar with homelessness based on personal experience or professional commitment, and to highlight where the priorities of patients and professionals dedicated to their care converge or diverge.Methods: This qualitative exercise asked 26 homeless patients and ten provider/experts to rank 16 aspects of primary care using a card sort. Patient-level respondents (n=26 were recruited from homeless service organizations across all regions of the USA and from an established board of homeless service users. Provider/expert-level respondents (n=10 were recruited from veteran and non-veteran-focused homeless health care programs with similar geographic diversity.Results: Both groups gave high priority to accessibility, evidence-based care, coordination, and cooperation. Provider/experts endorsed patient control more strongly than patients. Patients ranked information about their care

  20. Medication transitions and polypharmacy in older adults following acute care

    Directory of Open Access Journals (Sweden)

    Gamble JM


    Full Text Available John-Michael Gamble,1,* Jill J Hall,2,* Thomas J Marrie,3 Cheryl A Sadowski,2 Sumit R Majumdar,4 Dean T Eurich5 1School of Pharmacy, Memorial University of Newfoundland, St John's, NL, 2Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, 3Faculty of Medicine, Dalhousie University, Halifax, NS, 4Faculty of Medicine and Dentistry, 5School of Public Health, University of Alberta, Edmonton, AB, Canada *These authors contributed equally to this work Background/objective: Medication changes at transitions of care and polypharmacy are growing concerns that adversely impact optimal drug use. We aimed to describe transitions and patterns of medication use before and 1 year after older patients were hospitalized for community-acquired pneumonia, the second-most common reason for admission in North America. Materials and methods: This was an analysis of a population-based clinical registry of patients treated in any of the six hospitals or seven emergency departments in Edmonton, Alberta, Canada, comprising 2,105 patients 65 years and older with community-acquired pneumonia who had survived at least 1 year. The prevalence of polypharmacy (five or more unique prescription drugs, as well as new use and persistence of common drug classes were assessed. Results: The mean age was 78 years (standard deviation 8 years, 50% were female, 62% were hospitalized, and 58% had severe pneumonia. Among the 2,105 patients, 949 (45% were using five or more medications prior to hospitalization, increasing to 1,559 (74% within 90 days postdischarge and remaining over 70% at 1 year. Overall, 1,690 (80% patients newly started and 1,553 (74% patients stopped at least one medication in the first 90 days of follow-up. The prevalence of the most common drug classes (ie, cardiovascular, alimentary/metabolism remained stable, with the exception of anti-infective agents, whereby 25% of patients were dispensed an anti-infective agent 3 months to 1 year

  1. A televideo exercise and nutrition program for children with acute lymphoblastic leukemia in maintenance therapy: design and methods

    Directory of Open Access Journals (Sweden)

    Gibson CA


    Full Text Available Cheryl A Gibson,1 Keith J August,2 Jerry L Greene,3 Stephen D Herrmann,4 Jaehoon Lee,5 Susan P Harvey,6 Kate Lambourne,3 Debra K Sullivan7 1Department of Internal Medicine, Division of General and Geriatric Medicine, University of Kansas Medical Center, KS, USA; 2Children's Mercy Hospital, MO, USA; 3Department of Health, Sport, and Exercise Sciences, University of Kansas, KS, USA; 4Children's Health Research Center, Sanford Research, SD, USA; 5Institute for Measurement, Methodology, Analysis and Policy, Texas Tech University, TX, USA; 6Center for Research on Learning, University of Kansas, KS, USA; 7Department of Dietetics and Nutrition, University of Kansas Medical Center, KS, USA Abstract: Changes in nutrient intake and decreased exercise resulting from cancer therapies as well as their side effects may be contributing factors in the increased body weight and differences in physical fitness observed in survivors of childhood acute lymphoblastic leukemia (ALL. This article will describe the study protocol for an intervention program designed to improve the physical activity and nutrition behaviors of ALL survivors. Twenty-four children aged between 4 years and 12 years with ALL will be randomized to a 6-month technology-based exercise and nutrition program (TLC4ALLKids or to enhanced usual care (eUC. The participants randomized to the TLC4ALLKids will participate in weekly, 1-hour coaching sessions on nutrition and physical activity and 1-hour physical activity classes delivered by group video conferencing. Participants will be provided with iPad tablets loaded with video conferencing software and the Healthy Lifestyle Tracking calendar to track daily nutrition and physical activity goals and weight. Both groups will be provided with Fitbit™ Zip to monitor physical activity. To assess feasibility, participant recruitment (achievement of proposed sample size, attendance (per weekly online sessions/assessment sessions, and adherence (number of

  2. Delivery characteristics and patients’ handling of two single-dose dry-powder inhalers used in COPD

    Directory of Open Access Journals (Sweden)

    Chapman KR


    Full Text Available Kenneth R Chapman1, Charles M Fogarty2, Clare Peckitt3, Cheryl Lassen3, Dalal Jadayel3, Juergen Dederichs4, Mukul Dalvi4, Benjamin Kramer5On behalf of the INDEED (indacaterol: handling and preference evaluation of the Breezhaler device in COPD study investigators1University of Toronto, Toronto, Canada; 2Spartanburg Medical Research, Spartanburg, SC, United States; 3Novartis Horsham Research Centre, Horsham, West Sussex, UK; 4Novartis Pharma AG, Basel, Switzerland; 5Novartis Pharmaceuticals, East Hanover, NJ, USAAbstract: For optimal efficacy, an inhaler should deliver doses consistently and be easy for patients to use with minimal instruction. The delivery characteristics, patients’ correct use, and preference of two single-dose dry powder inhalers (Breezhaler and HandiHaler were evaluated in two complementary studies. The first study examined aerodynamic particle size distribution, using inhalation profiles of seven patients with moderate to very severe chronic obstructive pulmonary disease (COPD. The second was an open-label, two-period, 7-day crossover study, evaluating use of the inhalers with placebo capsules by 82 patients with mild to severe COPD. Patients’ correct use of the inhalers was assessed after reading written instructions on Day 1, and after training and 7 days of daily use. Patients’ preference was assessed after completion of both study periods. Patient inhalation profiles showed average peak inspiratory flows of 72 L/minute through Breezhaler and 36 L/minute through HandiHaler. For Breezhaler and HandiHaler, fine particle fractions were 27% and 10%, respectively. In the second study, correct use of Breezhaler and HandiHaler was achieved by >77% of patients for any step after 7 days; 61% of patients showed an overall preference for Breezhaler and 31% for HandiHaler (P = 0.01. Breezhaler is a low-resistance inhaler suitable for use by patients with a range of disease severities. Most patients used both inhalers correctly

  3. Safety of indacaterol in the treatment of patients with COPD

    Directory of Open Access Journals (Sweden)

    Donohue JF


    Full Text Available James F Donohue1, Dave Singh2, Oliver Kornmann3, David Lawrence4, Cheryl Lassen4, Benjamin Kramer5 1University of North Carolina, Chapel Hill, NC, USA; 2University of Manchester, Medicines Evaluation Unit, Manchester, UK; 3IKF Pneumologie GmbH and Co KG, Clinical Research Centre Respiratory Diseases, Frankfurt, Germany; 4Novartis Horsham Research Centre, Horsham, UK; 5Novartis Pharmaceuticals Inc, East Hanover, New Jersey, USA Purpose: Pooled data were analyzed to evaluate the safety and tolerability of indacaterol, a once-daily inhaled long-acting ß2-agonist for chronic obstructive pulmonary disease (COPD. Patients and methods: Data were pooled from clinical studies of 3–12 months’ duration in patients with moderate-to-severe COPD receiving double-blind indacaterol 75 µg (n = 449, 150 µg (n = 2611, 300 µg (n = 1157, or 600 µg once daily (n = 547; formoterol 12 µg twice daily (n = 556; salmeterol 50 µg twice daily (n = 895; placebo (n = 2012; or tiotropium 18 µg once daily, given open label or blinded (n = 1214. Outcomes were adverse events, serious adverse events and deaths, plasma potassium, blood glucose, and QTc interval and vital signs. Results: The commonest adverse events with indacaterol were COPD worsening, nasopharyngitis, and headache; most cases were mild or moderate and incidence was generally similar to placebo and other active treatments. The risk of acute respiratory serious adverse events (leading to hospitalization, intubation, or death was not significantly increased with any of the active treatments compared with placebo. COPD exacerbation rates (analyzed in the intent-to-treat population were significantly reduced with all active treatments versus placebo. Hazard ratios versus placebo for major cardiovascular adverse events were <1 for all indacaterol doses. Notable values for vital signs and measures of systemic ß2-adrenoceptor activity were rare with indacaterol. The number of deaths adjusted per patient

  4. Psychometric evaluation of the Sheehan Disability Scale in adult patients with attention-deficit/hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Coles T


    Full Text Available Theresa Coles,1 Cheryl Coon,1 Carla DeMuro,1 Lori McLeod,1 Ari Gnanasakthy21Patient-Reported Outcomes, RTI Health Solutions, Research Triangle Park, NC, 2Novartis Pharmaceuticals, East Hanover, NJ, USAAbstract: Inattention and impulsivity symptoms are common among adults with attention-deficit/hyperactivity disorder (ADHD, which can lead to difficulty concentrating, restlessness, difficulty completing tasks, disorganization, impatience, and impulsiveness. Many adults with ADHD find it difficult to focus and prioritize. Resulting outcomes, such as missed deadlines and forgotten engagements, may ultimately impact the ability to function at work, school, home, or in a social environment. The European Medicines Agency guidelines for evaluating medicinal products for ADHD recommend inclusion of both functional outcomes, such as school, social, or work functioning, and outcomes related to symptoms of ADHD in clinical studies of novel medication primary efficacy endpoints. Due to its performance in other disease areas and the relevance of its items as evidenced by content validity analyses, the Sheehan Disability Scale (SDS was chosen to assess functional impairment in ADHD. The aim of this study was to investigate the psychometric properties of the SDS, used as a brief measure of functional impairment in a number of psychiatric disorders, in adult patients with ADHD. To the authors' knowledge, this is the first study to evaluate the reliability of the SDS (based on Cronbach's coefficient alpha and test-retest reliability, its validity (construct and known-groups validity, and its ability to detect change in this patient population. This study also established a preliminary responder definition for the SDS in this study population to determine when change can be considered clinically beneficial in a clinical trial setting. The psychometric results support the use of the SDS subscales (items 1–3 and total score (sum of items 1–3 in an ADHD

  5. Knowledge, Attitude and Health Seeking Behavior of Health Care Professionals regarding Breast and Cervical Cancer at Indian Medical College

    Directory of Open Access Journals (Sweden)

    Rajal Thaker*


    Full Text Available Research article Knowledge, Attitude and Health Seeking Behavior of Health Care Professionals regarding Breast and Cervical Cancer at Indian Medical College Rajal Thaker*,Kay Perrin**, Ellen Daley *** ,Cheryl Vamos ****,Pankaj Patel ***** * Associate Professor Obstetrics and Gynaecology, ***** Dean; Smt N H L Municipal Medical College, Ahmedabad 380 006, India. ** Associate Professor, *** Associate Professor, Co-Director, Center for Transdisciplinary Research in Women’s Health (CTR-WH, **** Research Assistant Professor, Associate Director; Center for Transdisciplinary Research in Women’s Health (CTR-WH; University of South Florida College of Public Health, USA Abstract Background: Women’s preventative health is a major public health issue across the globe. From prenatal care to post-menopausal screenings, women’s preventative care covers a wide spectrum of issues and topics. There is limited data on knowledge and practices of screening methods of breast and cervical cancers among female health care professionals in India. This study examines health care professionals’ knowledge and practices regarding breast and cervical cancer screenings in India. Material and Methods After clearance from Institutional Review Board (IRB of University of South Florida (USF and permission from Smt N H L Municipal Medical College (NHLMMC, a cross- sectional interview based survey was conducted amongst female teaching faculty and female consultants of NHLMMC, two affiliated teaching hospitals (Sheth V S General Hospital and Smt S C L General Hospital, and SBB college of Physiotherapy during the year 2010-2011. Conclusion Findings highlight the critical need for education and practice with regards to women’s preventive health care. Practice of Breast Self Examination (BSE and Pap test amongst the health care professionals was quite low; however, those who were 40 year or older were more conscious about their health. Findings also highlight the need for

  6. Physicians’ use of computerized clinical decision supports to improve medication management in the elderly – the Seniors Medication Alert and Review Technology intervention

    Directory of Open Access Journals (Sweden)

    Alagiakrishnan K


    Full Text Available Kannayiram Alagiakrishnan,1 Patricia Wilson,2 Cheryl A Sadowski,3 Darryl Rolfson,1 Mark Ballermann,4,5 Allen Ausford,6,7 Karla Vermeer,7 Kunal Mohindra,8 Jacques Romney,9 Robert S Hayward10 1Department of Medicine, Division of Geriatric Medicine, 2Department of Medicine, 3Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, 4Chief Medical Information Office, Alberta Health Services, 5Division of Critical Care, Department of Medicine, University of Alberta, 6Department of Family Medicine, University of Alberta, 7Lynwood Family Physician, 8eClinician EMR, Alberta Health Services-Information Systems, 9Department of Medicine, Division of Endocrinology, 10Division of General Internal Medicine, University of Alberta, Edmonton, AB, Canada Background: Elderly people (aged 65 years or more are at increased risk of polypharmacy (five or more medications, inappropriate medication use, and associated increased health care costs. The use of clinical decision support (CDS within an electronic medical record (EMR could improve medication safety.Methods: Participatory action research methods were applied to preproduction design and development and postproduction optimization of an EMR-embedded CDS implementation of the Beers’ Criteria for medication management and the Cockcroft–Gault formula for estimating glomerular filtration rates (GFR. The “Seniors Medication Alert and Review Technologies” (SMART intervention was used in primary care and geriatrics specialty clinics. Passive (chart messages and active (order-entry alerts prompts exposed potentially inappropriate medications, decreased GFR, and the possible need for medication adjustments. Physician reactions were assessed using surveys, EMR simulations, focus groups, and semi-structured interviews. EMR audit data were used to identify eligible patient encounters, the frequency of CDS events, how alerts were managed, and when evidence links were followed.Results: Analysis of

  7. Public–private partnerships improve health outcomes in individuals with early stage Alzheimer’s disease

    Directory of Open Access Journals (Sweden)

    Galvin JE


    Full Text Available James E Galvin,1 Magdalena I Tolea,1 Nika George,2 Cheryl Wingbermuehle31Alzheimer Disease Center, Departments of Neurology, Psychiatry and Population Health, New York University Langone Medical Center, New York, NY, USA; 2Clinical Psychology Program, University of Missouri – St Louis, 3Alzheimer’s Association, St Louis Chapter, St Louis, MO, USAPurpose: In a collaborative effort between the Missouri Department of Health, Area Agencies on Aging (AAA, Alzheimer Association, and academic researchers, we tested whether early dementia detection and comprehensive care consultations would improve health outcomes in care receivers (CRs and their family caregivers (FCGs, therefore addressing an important public health concern.Participants and methods: A total of 244 community-dwelling older adults screened for early-stage dementia by the AAA field staff were referred to the Alzheimer Association and participated in Project Learn MORE (Missouri Outreach and Referral Expanded (PLM – a 2-year, nonrandomized multisite intervention consisting of comprehensive care consultations to improve coping skills. PLM participants were compared against 96 controls receiving the Alzheimer Association’s “usual services” between January 2011 and December 2012. We examined CR and FCG outcomes, including burden, care confidence, and mood, as effects of PLM, on delaying transitions in level of care.Results: CRs showed improved knowledge (P=0.002 and reduced depression (P=0.007, while FCGs demonstrated improved knowledge (P=0.003 and ability to identify sources of support for the CR (P=0.032 and for themselves (P=0.043. However, FCGs were more burdened after PLM (P=0.02, due to increased awareness of Alzheimer’s disease. PLM delayed transitions in care (odds ratio [OR] 3.32, 95% confidence level [CI]: 1.25–8.83 with the number needed to treat =6.82.Conclusion: PLM was successful in improving detection of incident cases of dementia in the community

  8. Proceedings of Patient Reported Outcome Measure’s (PROMs Conference Sheffield 2016: advances in patient reported outcomes research

    Directory of Open Access Journals (Sweden)

    Tim Croudace


    longitudinal parameter shifts in epidemiological data: measurement invariance and response shifts in cohort and survey data describing the UK’s Quality of Life Jan R. Boehnke O12 Patient-reported outcomes within health technology decision making: current status and implications for future policy Andrew Trigg, Ruth Howells O13 Can social care needs and well-being be explained by the EQ-5D? Analysis of Health Survey for England dataset Jeshika Singh, Subhash Pokhrel, Louise Longworth O14 Where patients and policy meet: exploring individual-level use of the Long-Term Conditions Questionnaire (LTCQ Caroline Potter, Cheryl Hunter, Laura Kelly, Elizabeth Gibbons, Julian Forder, Angela Coulter, Ray Fitzpatrick, Michele Peters

  9. "Presumed fair: Ironic effects of organizational diversity structures": Correction to Kaiser et al. (2013). (United States)


    Reports an error in "Presumed fair: Ironic effects of organizational diversity structures" by Cheryl R. Kaiser, Brenda Major, Ines Jurcevic, Tessa L. Dover, Laura M. Brady and Jenessa R. Shapiro (Journal of Personality and Social Psychology, 2013[Mar], Vol 104[3], 504-519). In the article, a raw data merging error in one racial discrimination claim condition from Experiment 6 inadvertently resulted in data analyses on an inaccurate data set. When the error was discovered by the authors and corrected, all analyses reported in Experiment 6 for claim validity, seriousness of the claim, and support for the claimant were inaccurate and none were statistically significant. The conclusions should be altered to indicate that participants with management experience who reflected on their own workplace diversity policies did not show the predicted effects. The literature review, remaining five studies, and remaining conclusions in the article are unaffected by this error. Experiment 6 should also report that 26.4% (not 26.4.7%) of participants had a graduate degree and eight participants (not 8%) did not provide educational data. Experiment 5 should have referred to the claim validity measure as a six-item measure ( .92) rather than a five-item measure; analyses on claim validity are accurate in text. Table 2's note should have said standard errors, not standard deviations. (The following abstract of the original article appeared in record 2012-31077-001.) This research tests the hypothesis that the presence (vs. absence) of organizational diversity structures causes high-status group members (Whites, men) to perceive organizations with diversity structures as procedurally fairer environments for underrepresented groups (racial minorities, women), even when it is clear that underrepresented groups have been unfairly disadvantaged within these organizations. Furthermore, this illusory sense of fairness derived from the mere presence of diversity structures causes high

  10. Obituary: Michael James Ledlow, 1964-2004 (United States)

    Puxley, Philip John; Grashuis, Randon M.


    wide variety of interests including a wonderfully diverse taste in music and an exceptional talent for home brewing beer. Mike was one of those rare individuals, enthusiastic and driven by his work at the Observatory as well as by his personal research, and with the skills to deliver in both aspects. His devotion to the Observatory and to research was surpassed only by that for his family. He is survived by his wife Cheryl, their two children Alexandria ("Andrea") and Abigail ("Abi"), three stepdaughters Mandy, Memoree and Misty and his sister Lisa Gay Gilmore.

  11. PREFACE: Specical issue on reflectometry (United States)

    Schüller, F. C.


    I would firstly like to convey my best wishes for 2006 to our readers, authors and referees. There are also some issues that I would like to communicate to you in this first issue of the new year. Farewell to Editorial Board members In 2005 the terms of office of half the Editorial Board came to an end. We would like to thank them for their wise advice on difficult questions, the innumerable cases where they have acted as adjudicators and for the many other forms of support they have given to the journal. While we say farewell to them as Board members, we trust that they will continue to support Nuclear Fusion. H. Bolt M.J. Fujiwara G.T. Hoang G.S. Lee S. Nakai R.R. Parker O.S. Pavlichenko S.C. Prager V.P. Smirnov M.Q. Tran Y. Wan Our special thanks go to F. (Rip) Perkins who chaired the Board for many years and was instrumental in many important Board decisions. We welcome the new members of the Editorial Board which met in its new composition (see the prelim pages) during the EPS conference in Tarragona under the chairmanship of M. Kikuchi. Refereeing As we did last year we would like to thank our top ten most loyal referees who have helped the journal with its double-referee peer-review procedure in the last year. At the Nuclear Fusion Editorial Office we are fully aware of the load we put on the shoulders of our referees. At the end of 2004 the Editorial Board decided that a gesture of gratitude should be made to our top ten most loyal referees. We offer them a personal subscription to Nuclear Fusion with electronic access for one year, free of charge. To select the top ten referees we have adopted the criterion that a researcher should have acted as a referee or adjudicator for at least three different manuscripts during the period autumn 2004 to autumn 2005. According to our records the following people, excluding our Board members, met this criterion. Congratulations and many, many thanks! D. van Eester (ERM/KMS, Belgium) L.R. Grisham (PPPL, USA) C. Hidalgo

  12. Energy land M-V. Use of regenerative energy sources and hydrogen technology 2011. Proceedings; Energieland M-V. Nutzung regenerativer Energiequellen und Wasserstofftechnik 2011. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    Luschtinetz, Thomas; Lehmann, Jochen (eds.)


    energies (K. Wozniak); (39) Possibilities of the reduction of ship emissions during stays at port (W. Zenczak); (40) Investigations on the advanced alkaline pressure electrolysis at the Hydrogen Research Centre Cottbus (C. Ziems); (41) Hydrogen mobility: In the German Clean Energy Partnership (CEP) strong partners are jointly developing the fuel of the future (presentation CEP); (42) Small vehicles with H2 BZ propulsion - a practically oriented project of innovative small and medium-sized enterprises in the electro mobility area (presentation LBST); (43) Fro measurement to knowledge - Measurement data acquisition for renewable energies (presentation WERUM).

  13. 2012 best practices for repositories collection, storage, retrieval, and distribution of biological materials for research international society for biological and environmental repositories. (United States)


    Third Edition [Formula: see text] [Box: see text] Printed with permission from the International Society for Biological and Environmental Repositories (ISBER) © 2011 ISBER All Rights Reserved Editor-in-Chief Lori D. Campbell, PhD Associate Editors Fay Betsou, PhD Debra Leiolani Garcia, MPA Judith G. Giri, PhD Karen E. Pitt, PhD Rebecca S. Pugh, MS Katherine C. Sexton, MBA Amy P.N. Skubitz, PhD Stella B. Somiari, PhD Individual Contributors to the Third Edition Jonas Astrin, Susan Baker, Thomas J. Barr, Erica Benson, Mark Cada, Lori Campbell, Antonio Hugo Jose Froes Marques Campos, David Carpentieri, Omoshile Clement, Domenico Coppola, Yvonne De Souza, Paul Fearn, Kelly Feil, Debra Garcia, Judith Giri, William E. Grizzle, Kathleen Groover, Keith Harding, Edward Kaercher, Joseph Kessler, Sarah Loud, Hannah Maynor, Kevin McCluskey, Kevin Meagher, Cheryl Michels, Lisa Miranda, Judy Muller-Cohn, Rolf Muller, James O'Sullivan, Karen Pitt, Rebecca Pugh, Rivka Ravid, Katherine Sexton, Ricardo Luis A. Silva, Frank Simione, Amy Skubitz, Stella Somiari, Frans van der Horst, Gavin Welch, Andy Zaayenga 2012 Best Practices for Repositories: Collection, Storage, Retrieval and Distribution of Biological Materials for Research INTERNATIONAL SOCIETY FOR BIOLOGICAL AND ENVIRONMENTAL REPOSITORIES (ISBER) INTRODUCTION T he availability of high quality biological and environmental specimens for research purposes requires the development of standardized methods for collection, long-term storage, retrieval and distribution of specimens that will enable their future use. Sharing successful strategies for accomplishing this goal is one of the driving forces for the International Society for Biological and Environmental Repositories (ISBER). For more information about ISBER see . ISBER's Best Practices for Repositories (Best Practices) reflect the collective experience of its members and has received broad input from other repository professionals. Throughout this document

  14. Experimenting with Educational Games using the Xbox, PC, and iPad (United States)

    Rohrlick, D.; Kilb, D. L.; Peach, C. L.; Simms, E.; Yang, A.; Layman, C.; Deutscher, R.


    Daniel Rohrlick, Alan Yang, Eric Simms, Debi Kilb, Cheryl Peach, Charina Layman, Rebecca Deutscher 1. Scripps Institution of Oceanography, La Jolla, CA, USA 2. Harvard University Center for the Environment, Cambridge, MA, USA 3. Birch Aquarium at Scripps, La Jolla, CA, USA 4. The Lawrence Hall of Science, University of California Berkeley, Berkeley, CA, USA As videogames continue to grow in popularity, especially with today's youth, it is becoming clear that gaming can be a potent learning tool. But what is the best way to engage a player in learning from a videogame? Based on our five years of developing and testing our own educational games, we experimented with various forms of gaming techniques and player interaction. Our first game, "Deep-sea Extreme Environment Pilot (DEEP)", is an Xbox 360 game where players learn about deep-sea environments while controlling a Remotely Operated Vehicle (ROV). DEEP is a "traditional" videogame where players interact with a controller and a TV screen. The second game we developed for the PC is called the "Quake Catcher Network (QCN)" game. With the gameplay focused on earth sciences, players must quickly deploy seismic sensors to record aftershocks from a large earthquake. Instead of using a game controller to play the QCN game, we instead incorporate the Microsoft Kinect motion sensor for the game input. Finally, the "Glider Game" is our third and most recent game designed for use on the mobile device platform such as iPods and iPads. In this game players control ocean gliders and must complete missions while battling ocean currents, power consumption, and other unanticipated problems. Here, the gameplay is aimed toward the casual gamer using touch-screen based controls in the hope that players can easily pick up and play this game with little gaming experience. After testing our games numerous times in museums, informal science learning centers, and classrooms we have been able to track qualitatively which educational

  15. Obituary: Ludwig Friedrich Oster, 1931-2003 (United States)

    Sofia, Sabatino; Altschuler, Martin D.


    Ludwig Friedrich Oster died at the Anchorage Nursing and Rehabilitation Center in Salisbury, MD on 28 February 2003, of complications from advanced Alzheimer's disease. He is survived by his wife Cheryl M. (Oroian) and his two children by a previous marriage, Ulrika and Mattias Oster. He had a distinguished career both as a researcher in solar physics and as a science administrator in the National Science Foundation. Ludwig was born on 8 March 1931 in Konstanz, Germany and emigrated to the U.S. in 1958, acquiring American citizenship in 1963. His mother and father were Emma Josefine (Schwarz) and Ludwig Friedrich Oster. He got a BS degree in physics at the University of Freiburg under the guidance of Prof. K. O. Kiepenheuer in 1951, and a MS (1954) and PhD from the University of Kiel in 1956 under the guidance of Prof. A. Unsold. From 1956 to 1958 he was a Fellow of the German Science Council at Kiel and, upon his arrival to the US in 1958, he became a Postdoctoral Research Associate in the Physics Department of Yale University. He became an Assistant Professor of Physics and Astrophysics at Yale in 1960 and five years later he was promoted to Associate Professor. In 1967 he became an Associate Professor of Physics and Astrophysics at the University of Colorado and a Fellow of the Joint Institute for Laboratory Astrophysics; he was promoted to Full Professor in 1970. In 1981 he was a Visiting Professor at Johns Hopkins University, and shortly thereafter became a National Research Council Senior Associate at NASA/Goddard Space Flight Center in Greenbelt, MD, where he worked on solar variability. He joined the National Science Foundation in 1983, where he became the Program Manager for the National Radio Astronomy Observatory in the Division of Astronomical Sciences of the Foundation; he remained there until his retirement in 1996. His early work, started in Germany and continued at Yale, concerned radiation mechanisms related to solar phenomena. His works on

  16. Selected abstracts from the Breastfeeding and Feminism International Conference 2016

    Directory of Open Access Journals (Sweden)

    Lisa H. Amir


    Full Text Available Table of contents A1. Infant feeding and poverty: a public health perspective in a global context Lisa H. Amir A2. Mothers’ experiences with galactagogues for lactation: an exploratory cross sectional study Alessandra Bazzano, Shelley Thibeau, Katherine P. Theall A3. The motherhood journey and breastfeeding: from self-efficacy to resilience and social stigma Anna Blair, Karin Cadwell A4. Breastfeeding as an evolutionary adaptive behavior Emily A. Bronson A5. Conflict-of-interest in public health policy: as real as that logo on your website Elizabeth C. Brooks A6. Co-opting sisterhood and motherhood: behind the scenes of Similac’s aggressive social media campaigns Jodine Chase A7. The exclusion of women from the definition of exclusive breastfeeding Ellen Chetwynd, Rebecca Costello, Kathryn Wouk A8. Healthy maternity policies in the workplace: a state health department’s experience with the “Bring Your Infant to Work” program Lindsey Dermid-Gray A9. Implications for a paradigm shift: factors related to breastfeeding among African American women Stephanie Devane-Johnson, Cheryl Woods Giscombe, Miriam Labbok A10. Social experiences of breastfeeding: building bridges between research and policy: an ESRC-funded seminar series in the UK Sally Dowling A11. Manager’s perspectives of lactation breaks Melanie Fraser A12. The challenging second night: a dialogue from two perspectives Jane Grassley, Deborah McCarter-Spaulding, Becky Spencer A13. The role of lactation consultants in two council breastfeeding services in Melbourne, Australia – some preliminary impressions Jennifer Hocking, Pranee Liamputtong A14. Integrating social marketing and community engagement concepts in community breastfeeding programs Sheree H. Keitt, Harumi Reis-Reilly A15. What happens before and after the maternity stay? Creating a community-wide Ten Steps approach Miriam Labbok A16. #RVABREASTFEEDS: cultivating a breastfeeding-friendly community Leslie Lytle A17

  17. Dancing around the Black Hole (United States)


    were born" . Agreement between observations and models This interesting scenario is supported by recent, extensive model computations by the team. In these computer models, large numbers of "stars" (mass points) move in a model galaxy with both a large and a nuclear bar, as observed in the three galaxies. Herve Wozniak refers to them as "self-consistent N-body simulations" and explains why the team is enthusiastic: "When our models also include star formation in the gas in the central region, a new, "dynamically cool" component of young stars emerges and mixes with the old stellar population" . He goes on: "The light from those young stars is superposed on that from the older ones in that area. Because of this, the overall "velocity dispersion" in the central region is then smaller than what it is further out. This is exactly as we observed in the ISAAC spectra obtained in the present programme" . Eric Emsellem points out that such a "dynamically cold" system is unstable and cannot last very long . "Soon it will "heat up" due to complex dynamical processes. It is quite possible that some of these stars will eventually end up as food for the hungry Black Hole.." Prospects With these new high-resolution infrared observations of the structure and the objects in the innermost regions of active galaxies, ISAAC and the VLT are paving the way for future studies of the processes that take place in the immediate neighbourhood of the central black holes. More active galaxies will now be observed with this method and it will be interesting to see if the presently discovered "cool" and young stellar systems represent a common phenomenon or not. More information The first stages of the research project reported in this Press Release are described in a scientific article ("Dynamics of embedded bars and the connection with AGN" by E. Emsellem et al.) that appeared in the European research journal Astronomy & Astrophysics (Vol. 368, p. 52). Two other articles about the new models and

  18. Obituary: Frank Culver Jones, 1932-2007 (United States)

    Ormes, Johnathan F.; Streitmatter, Robert E.


    everyone from technicians to scientists and managers. This generosity resulted in his becoming the first senior research scientist to be honored with the Laboratory's Peer Award. Survivors include his wife of 52 years, Ardythe Grube Jones of Silver Spring, Maryland, two children, Cheryl Mattis of Columbia and Timothy Jones of Silver Spring, two brothers, and four grandchildren.

  19. Preface: SciDAC 2009 (United States)

    Simon, Horst


    and posters goes to the teams of researchers, the success of this year's conference is due to the strong efforts and support from members of the 2009 SciDAC Program Committee and Organizing Committee, and I would like to extend my heartfelt thanks to them for helping to make the 2009 meeting the largest and most successful to date. Program Committee members were: David Bader, LLNL; Pete Beckman, ANL; John Bell, LBNL; John Boisseau, University of Texas; Paul Bonoli, MIT; Hank Childs, LBNL; Bill Collins, LBNL; Jim Davenport, BNL; David Dean, ORNL; Thom Dunning, NCSA; Peg Folta, LLNL; Glenn Hammond, PNNL; Maciej Haranczyk, LBNL; Robert Harrison, ORNL; Paul Hovland, ANL; Paul Kent, ORNL; Aram Kevorkian, SPAWAR; David Keyes, Columbia University; Kwok Ko, SLAC; Felice Lightstone, LLNL; Bob Lucas, ISI/USC; Paul Mackenzie, Fermilab; Tony Mezzacappa, ORNL; John Negele, MIT; Jeff Nichols, ORNL; Mike Norman, UCSD; Joe Oefelein, SNL; Jeanie Osburn, NRL; Peter Ostroumov, ANL; Valerio Pascucci, University of Utah; Ruth Pordes, Fermilab; Rob Ross, ANL; Nagiza Samatova, ORNL; Martin Savage, University of Washington; Tim Scheibe, PNNL; Ed Seidel, NSF; Arie Shoshani, LBNL; Rick Stevens, ANL; Bob Sugar, UCSB; Bill Tang, PPPL; Bob Wilhelmson, NCSA; Kathy Yelick, NERSC/LBNL; Dave Zachmann, Vista Computational Technology LLC. Organizing Committee members were: Communications: Jon Bashor, LBNL. Contracts/Logistics: Mary Spada and Cheryl Zidel, ANL. Posters: David Bailey, LBNL. Proceedings: John Hules, LBNL. Proceedings Database Developer: Beth Cerny Patino, ANL. Program Committee Liaison/Conference Web Site: Yeen Mankin, LBNL. Tutorials: David Skinner, NERSC/LBNL. Visualization Night: Hank Childs, LBNL; Valerio Pascucci, Chems Touati, Nathan Galli, and Erik Jorgensen, University of Utah. Again, my thanks to all. Horst Simon San Diego, California June 18, 2009

  20. News & Announcements (United States)


    News from Journal House National Chemistry Week (NCW) Celebrating Chemistry and Art is the theme of NCW 2001, to be held November 4-10, 2001. As you make plans for participating in the celebrations in your area, keep in mind that JCE is developing special materials on this theme, which will appear in our October issue: Classroom Activities, a comprehensive Illustrated Resource Paper, Report from Online, specially written brief articles illustrated in color, articles related to the theme, and CLIPs (Chemical Laboratory Information Profiles). Awards Announced Passer Award Passer Award recipients from the April 1 closing date are: George Bennett, Millikin University, Decatur, IL Daniel Berger, Bluffton College, Bluffton, OH Karen Dunlap, Sierra College, Rocklin, CA Myung-Hoon Kim, Georgia Perimeter College, Dunwoody, GA Cheryl Longfellow, Philadelphia University, Philadelphia, PA Jerry Maas, Oakton Community College, Des Plaines, IL Tim Royappa, University of West Florida, Pensacola, FL Visiting Scientist Award, Western Connecticut Section Diane Bunce, The Catholic University of America, has been selected as the 2001 Visiting Scientist of the Western Connecticut Section of the ACS. The award, presented annually since 1967, brings an outstanding chemical educator to visit high schools in Fairfield County, CT. In May, Bunce visited three high schools, Christian Heritage School, Fairfield High School, and Greenwich High School, where she interacted with teachers and students and presented lectures and demonstrations to several chemistry classes. She was also keynote speaker at the ACS local section's Education Night. The awardee is selected by a committee of university and high school teachers, industrial chemists, and the previous Visiting Scientist; there is an honorarium of 1500 plus expenses. Welch Award Roger D. Kornberg, a professor of structural biology at the Stanford University School of Medicine, received the 2001 Welch Award for his discovery of the nucleosome

  1. News & Announcements (United States)


    for travel awards for post-doctoral, graduate, and undergraduate women to make their first research presentation at a national meeting sponsored by Eli Lilly & Co. For more information and an application form, contact your department chair;; or Cheryl Brown, ACS, 1155 16th Street, NW, Washington, DC 20036; phone: 800/227-5558 ext. 6022; email The deadline for receipt of applications for meetings between January 1 and June 30, 2000, is October 15, 1999; for meetings between July 1 and December 31, 2000, the deadline is March 15, 2000. Call for Symposia, Papers, Workshops: 16th BCCE The 16th Biennial Conference on Chemical Education will be held July 30­August 3, 2000, at the University of Michigan in Ann Arbor. The conference Web site at bcce is ready to accept proposals for symposia, papers, posters, and workshops. Or proposals may be submitted in writing to the Program Chair, Brian Coppola, phone: 734/764-7329; email: The deadline for submission of proposals for symposia and workshops is December 13, 1999; the deadline for submission of abstracts of papers and posters is February 4, 2000. For general information contact Seyhan Ege, phone: 734/764-7340; email: 16th IUPAC Conference on Chemical Thermodynamics 16th IUPAC Conference on Chemical Thermodynamics (concurrent with 55th Calorimetry Conference and 10th Symposium on Thermodynamics of Nuclear Materials) August 6­11, 2000 Halifax, Nova Scotia, Canada This conference will cover research topics in all areas of thermodynamics. In addition, there will be a special poster session for papers on two aspects of thermodynamics education: lecture demonstrations and undergraduate laboratory experiments. Come and join us for lobster and learn what is new and exciting in thermodynamics. To be on the email list for this meeting, send a message to: ICCT@IS.DAL.CA. For further details, consult the conference Web site