WorldWideScience

Sample records for grand manner painters

  1. Grand Manner Aesthetics in Landscape: From Canvas to Celluloid

    Auger, Emily E.

    2009-01-01

    The methods by which environmental issues are aestheticized in late-twentieth-century film is directly and historically related to those established for grand manner painters by Nicholas Poussin (1594-1665) and taught at the French academy from the seventeenth through the nineteenth centuries. That these fundamentals were part of the training of…

  2. Unjustly forgotten painter

    Marković Kamenko M.

    2010-01-01

    Full Text Available This paper talks about a painter, Sima Čemerikić, whose miscellaneous and rich work, due to unexplained circumstances, has remained out of reach of professional and general public until now. He was born in 1906 in Prizren where he completed junior high-school in 1923. Afterwards, he moved to Skopje. He entered a state School of Art in Belgrade in 1924. Having graduated in 1929 he spent a short time training in Venice. Upon his arrival in Skopje, his artistic career began. Along with other painters from Macedonia, he equally fills the pages of Macedonian modern art. He remained in this city until the capitulation of that country. The other part of his life, from 1941 to his death in 1973, he spent in Niš. The work of Sima Čemerikić is separated into two periods. The first one, from Skopje, lasted from his graduation from the Art School in 1929 to the beginning of the World War II. The second period, from Niš, begins after his family had moved to Niš and ends with his death in 1973. He left hundreds of drawings and a number of paintings behind as well as a dozen of pastels and hundreds of aquarelles. Let me mention some of the paintings: Landscape of the sea, Landscape of Makarska, A Theme from Bol on Brač, Pain, A Little Gypsy, Portrait of The Sister, Fish, Chrysanthemum, Roses, Books and Apples, Tulips.

  3. Measurements of respiratory illness among construction painters.

    White, M C; Baker, E L

    1988-01-01

    The prevalence of different measurements of respiratory illness among construction painters was examined and the relation between respiratory illness and employment as a painter assessed in a cross sectional study of current male members of two local affiliates of a large international union of painters. Respiratory illness was measured by questionnaire and spirometry. Longer employment as a painter was associated with increased prevalence of chronic obstructive disease and an interactive eff...

  4. Dr Valter Rukavina - amateur painter.

    Glavocic, Daina

    2008-01-01

    In this essay Dr Valter Rukavina (Rijeka 1896-1972), excellent specialist in infectious diseases and professor of the Rijeka University School of Medicine, is presented as successful amateur painter. He had been refining his talent through relentless practice since the school days, complementing it with skills and advice from established painters he associated with. He favoured figurative, realistic and somewhat romantic expression for his themes such as coastal landscapes, marinas, Quarnero sceneries, still life in tempera or oil, and drawings in ink or sepia. Despite partial colour blindness, he successfully used colour. He featured in a number of group exhibitions such as that of amateur painters of Rijeka in 1950, of painters physicians of Yugoslavia (Zagreb, 1956), in the Second International Exhibition of Contemporary Art (Florence, 1964), exhibition of the Rijeka branch of the Croatian Association of Visual Artists (Belgrade, 1966), and the 1969 exhibition in Opatija. His native city hosted two one-man exhibitions, the first retrospective in 1971, while he was still alive, and the second posthumous in 2007, with a good selection of his life's work.

  5. Measurements of respiratory illness among construction painters.

    White, M C; Baker, E L

    1988-08-01

    The prevalence of different measurements of respiratory illness among construction painters was examined and the relation between respiratory illness and employment as a painter assessed in a cross sectional study of current male members of two local affiliates of a large international union of painters. Respiratory illness was measured by questionnaire and spirometry. Longer employment as a painter was associated with increased prevalence of chronic obstructive disease and an interactive effect was observed for smoking and duration of employment as a painter. Multiple regression analysis showed a significant association between years worked as a painter and a decrement in FEV1 equal to about 11 ml for each year worked. This association was larger among painters who had smoked. The prevalence of chronic bronchitis was significantly associated with increased use of spray application methods.

  6. Painter 11 Creativity Digital Artist's Handbook

    Sutton, Jeremy

    2009-01-01

    Jeremy Sutton is one of the world’s premier Painter artists (www.JeremySutton.com and www.PaintboxJ.com), and in this brand new edition of his best-selling Painter Creativity: Digital Artist’s Handbook, he shows you the methods and techniques he’s developed over the years to perfect his art and earn him the title of Corel Painter Master. This edition has been completely revamped to cover all of the new features in Corel Painter 11 and the Wacom Intuos4 pen-tablet, including: .. *The new Hard Media brushes .. *Complete visual summary of all brushes, new and old, in Painter 11 .. *Revised and up

  7. Florence Kelley and the radium dial painters

    Cloutier, R.J.

    1980-01-01

    All health physicists are familiar with the radium dial painter episode of the early 1900s and how one of today's primary radiation limits was set after studying both the health effects of these workers. The social history of this event is not as well known to health physicists. This paper tells of the efforts by Florence Kelley of the National Consumers League and others on behalf of the dial painters and of the events that led to Kelley's interest in the problem. Known as the 'Impatient Crusader', Florence Kelley worked to have legislation passed that would eliminate the radiation hazards of dial painting and to obtain compensation for those who were injured. (author)

  8. Overview of occupational cancer in painters in Korea.

    Myong, Jun-Pyo; Cho, Younmo; Choi, Min; Kim, Hyoung-Ryoul

    2018-01-01

    Comprehensive consideration is necessary for setting guidelines to evaluate evidence of occupational cancer in painters due to work-related exposure to carcinogens in paint (a phenomenon termed herein as "work-relatedness"). The aim of the present research is to perform a comprehensive review and to suggest criteria for the provision of compensation for occupational neoplasm among painters in Korea. In order to perform a comprehensive review, this study assessed and evaluated scientific reports of carcinogenicities from the International Agency for Research on Cancer (IARC) and the Industrial Injuries Advisory Council (IIAC), as well as reviewed the existing literature about occupational exposure among painters in Korea and the epidemiologic investigations of claimed cases of cancer among painters in Korea. The IARC declares that occupational exposures in commercial painting are classified as Group 1 carcinogens for lung cancer and bladder cancer among painters. The epidemiologic studies show consistent causal relationships between occupational exposure in painters and cancers such as lung cancer [meta relative risk: 1.34 (95% confidence intervals (CIs): 1.23-1.41)] and bladder cancer [meta relative risk: 1.24 (95% CIs: 1.16-1.33)]. In reviewing occupational cancer risks for commercial painters, the Industrial Injuries Advisory Council (IIAC) confirms occupational cancer risks for lung and bladder cancer among commercial painters. According to the IIAC, however, the elevated cancer risks reported in existing literature are not doubled in either lung or bladder cancer in commercial painters relative to the risks of these cancers in the general population. Based on our review of existing Korean articles on the topic, painters are exposed to potential carcinogens including polycyclic aromatic hydrocarbons (PAHs), benzene, hexavalent chrome, crystalized silica, asbestos, and other agents, and relative levels are estimated within commercial painting processes. However

  9. Adolf Sandoz, an Orientalist Painter in Algeria

    Wójcik, Agata

    2017-04-01

    Full Text Available Adolf Karol Sandoz was a 19th-century Polish artist who spent his life and developed his artistic career in France. In Paris, he studied painting and architecture, and worked as a professional illustrator. He can also be linked with a circle of artist-travellers, who searched for new sources of inspiration in the Orient. In 1879 and 1881, Sandoz travelled in Algeria. He described his impressions from the first journey in vividly written memoires published by the Krakow journal "Czas". His travels inspired several genre paintings, including: "Interior of a house in Biskra", "Dancer from the Uled Nail tribe", "Arab woman by a cradle", "Morning in the Sahara", "Evening in the Sahara", "Oasis", "On the Oued riverbank at El Kantara oasis", and "Sheik Mistress of El Kantara". At present, his works emerge at art auctions, are known from reproductions, or only from descriptions. Sandoz exhibited in Paris, Warsaw, Krakow, and Lviv, where he was appreciated by art critics. The aim of this article is to introduce Sandoz’s journey to Algeria, analyse his paintings with exotic subject matter, and locate them within a wider context of orientalist painting. It will also present the history of artistic travel to Algeria undertaken by 19th-century painters, including those from Poland.

  10. Coping with crisis. Career strategies of Antwerp painters after 1585

    David van der Linden

    2015-12-01

    Full Text Available This article explores how painters responded to the crisis on the Antwerp art market in the 1580s. Although scholarship has stressed the profound crisis and subsequent emigration wave, prosopographical analysis shows that only a minority of painters left the city. Demand for Counter-Reformation artworks allowed many to pursue their career in Antwerp, while others managed to survive the crisis by relying on cheap apprentices and the export of mass-produced paintings. Emigrant painters, on the other hand, minimised the risk of migration by settling in destinations that already had close artistic ties to Antwerp, such as Middelburg. Prosopographical analysis thus allows for a more nuanced understanding of artistic careers in the Low Countries.

  11. Polonium-210 concentration in the hair of 51 radium dial painters

    Erkang, Zeng; Nanxiang, Li

    1984-07-01

    The /sup 210/Po concentration in the hair of 51 radium dial painters (one group of 29 male, and the another group of 22 female) was reported in this paper. It was found that the /sup 210/Po concentration in the hair of both the male and female painters were significantly higher than that of the controls. A correlation has also been observed between the /sup 210/Po concentration in the hair and the working ages of the male painters.

  12. [Evaluation of various biochemical parameters in the urine and blood of painters in the carpentry business].

    Sołtys, M; Jakubowska, W; Lenart, E; Nagadowska, H; Lisiecka, M; Ziemer, I; Koćmierkska-Grodzka, D

    1986-01-01

    The work has been aimed at investigating the effects of organic solvent-toluene-upon the painters of the Building Joinery Factory. Studies carried out during 1978-1980 showed an increased level of toluene metabolite (hippuric acid) in painters' urine, as compared to the environmental control group. The highest level of hippuric acid in painters' urine was found in the first period (first six months) of their job. This was not related to an increase in toluene vapours at the workplace. In painters' blood some irregular and rather small modifications of enzymatic activity were exhibited.

  13. Austrian Painter Leopold Kupelwieser and Bishop Josip Juraj Strossmayer

    Ljerka Dulibić

    2016-01-01

    Full Text Available All 20th-century chronologies of the collector’s activity of Bishop Josip Juraj Strossmayer (1815-1905 and overviews of the evolution of today’s Strossmayer’s Gallery of Old Masters at the Croatian Academy of Sciences and Arts mention the bishop’s cooperation with the Austrian Nazarene painter Leopold Kupelwieser (1796-1862, father of Paul Kupelwieser, the former owner of the Brijuni islands. This episode from the “prehistory” of Strossmayer’s Gallery has hitherto been known only as a brief notice repeated in almost identical formulations: “In 1857, the bishop sent the first larger group of paintings to Vienna in order to be restored under the supervision of painter Leopold Kupelwieser.” Research of archival documents mentioning the cooperation between Bishop Strossmayer and painter Kupelwieser has now been complemented with an overview of Kupelwieser’s activity in Croatia, with an aim of promoting the preservation and evaluation of this segment of his painting oeuvre. Besides paintings ordered by Strossmayer (presently at the Diocesan Museum of Zagreb, Kupelwieser produced two paintings for Croatian churches independently of his cooperation with the bishop (for the church of St Stephen of Hungary, today’s church of the Immaculate Conception of the Blessed Virgin Mary in Nova Gradiška, and for the chapel of St Peter and Paul in Dvor na Uni. Two more paintings are preserved on the Brijuni islands that do not directly belong to Kupelwieser’s oeuvre yet are closely linked to him.

  14. Exposure Characteristics of Construction Painters to Organic Solvents

    Hyunhee Park

    2016-03-01

    Conclusion: From this study, we recognized that construction painters are exposed to various solvents, including carcinogens and reproductive toxins, and the levels of TVOC concentration in many of the painting tasks exceeded the exposure limits. Construction workers need to be protected from chemical agents during their painting works by using personal protective devices and/or work practice measures. Additional studies should focus on the exposure assessment of other hazards for construction workers, in order to identify high-risk tasks and to improve hazardous work environments.

  15. Male-mediated infertility in sons of building painters and gardeners

    Ramlau-Hansen, C H; Stoltenberg, C D G; Hougaard, K S

    2012-01-01

    To investigate whether sons of gardeners and building painters have increased risk of infertility in comparison with sons of bricklayers, carpenters and electricians.......To investigate whether sons of gardeners and building painters have increased risk of infertility in comparison with sons of bricklayers, carpenters and electricians....

  16. Effects of Personal Protective Equipment Use and Good Workplace Hygiene on Symptoms of Neurotoxicity in Solvent-Exposed Vehicle Spray Painters.

    Keer, Sam; McLean, Dave; Glass, Bill; Douwes, Jeroen

    2018-03-12

    To assess the association between the use of personal protective equipment (PPE) and good workplace hygiene and symptoms of neurotoxicity in solvent-exposed vehicle spray painters. Exposure control measures including PPE-use and workplace hygiene practices and symptoms of neurotoxicity were assessed in 267 vehicle repair spray painters. Symptoms were assessed using an adapted version of the EUROQUEST Questionnaire. Frequent respirator and glove use was inversely and significantly associated with symptoms of neurotoxicity in a dose-dependent manner (P 80%. Poor hygiene workplace practices, such as solvent exposure to multiple body parts (OR 3.4, P = 0.11 for reporting ≥10 symptoms), were associated with an increased risk of symptoms. When using a general workplace hygiene score derived from a combination of PPE-use and (good) workplace practice factors an inverse and significant dose-response trend was observed for reporting ≥5 (P hygiene are associated with a strongly reduced risk of symptoms of neurotoxicity in solvent-exposed vehicle spray painters.

  17. Icon Painters of the Nizhniy Novgorod Volga Region of the XVII Century

    Veronicka N. Belyaeva

    2012-09-01

    Full Text Available The author considers specificity and basic difficulties of biographies of the icon painters of the Nizhniy Novgorod Volga region of the XVII-th century restore. The data on the masters are cites.

  18. Occupational contact dermatitis in painters - an analysis of patch test data from the Danish Contact Dermatitis Group

    Mose, Anja P; Lundov, Michael Dyrgaard; Zachariae, Claus

    2012-01-01

    Background. Painters are among the occupational groups that most commonly experience occupational contact dermatitis, but few investigations exist concerning this occupation. Objectives. To characterize painters with contact dermatitis and identify the most common allergens associated...... with the occupation. Materials and methods. All patch test results of 219 painters and 1095 matched controls registered by the Danish Contact Dermatitis Group between 2001 and 2010 were analysed. Results. Hand eczema (p contact dermatitis (p

  19. Painters in the Splendor of Tunja: Naming Unrecognized Artists to Bring them out of Anonymity (XVI and XVII centuries

    Laura Liliana Vargas Murcia

    2017-07-01

    Full Text Available Tunja has stood out as one of the riches cities of New Kingdom of Granada, regarding the presence of painting in the last decades of the XVI century and the first half of the XVIIth. Its painters were of importance not only in this city but in the rest of the Province as well, with the churches and museums of Boyacá containing images that were essential elements in the indoctrination of indigenous communities. Civil mural works of art in Tunja have been an object of study mostly for their interpretation, and less regarding the identities of their makers. As far as easel painting, Angelino Medoro eclipsed the names of other artists who contributed to making Tunja one the the most representative cities of the Mannerism and Renaissance of Hispanic America. This article presents the names of some of the active painters of this period, their lives and production, seeking the recognition of these characters, whose names have been brought out of anonymity in the latest years. The starting point for the information search was the research of Magdalena Corradine Mora on the inhabitants of Tunja in the first decades of the XVII century, and the search for information in the Boyacá Regional Historical Archive. In calling attention upon these artists, we hope that, in the future, the identification of their works may be initiated as well as the research, conservation and dissemination of these works, due to the fact that this heritage is not always in ideal conditions, nor is it perceived and valued as is deserved.

  20. Sex differences in muscular load among house painters performing identical work tasks

    Meyland, Jacob; Heilskov-Hansen, Thomas; Alkjær, Tine

    2014-01-01

    PURPOSE: The present study aimed to estimate possible differences in upper body muscular load between male and female house painters performing identical work tasks. Sex-related differences in muscular load may help explain why women, in general, have more musculoskeletal complaints than men....... METHODS: In a laboratory setting, 16 male and 16 female house painters performed nine standardised work tasks common to house painters. Unilateral electromyography (EMG) recordings were obtained from the supraspinatus muscle by intramuscular electrodes and from the trapezius, extensor and flexor carpi...... radialis muscles by surface electrodes. Relative muscular loads in %EMGmax as well as exerted force in Newton, based on ramp calibrations, were assessed. Sex differences were tested using a mixed model approach. RESULTS: Women worked at about 50% higher relative muscular loads than men in the supraspinatus...

  1. Grandes remolques

    Editorial, Equipo

    1961-07-01

    Full Text Available El empleo creciente del material pesado auxiliar en la construcción de obras de ingeniería civil ha motivado la fabricación de grandes plataformas, capaces de transportar toda clase de maquinaria auxiliar. En general, este tipo de maquinaria requiere medios de transporte, pues su circulación por carreteras es lenta, obstructiva y cara, siempre que se trate de grandes distancias, caso presente en la mayoría de ocasiones en que se exige un traslado de esta maquinaria de una a otra obra.

  2. Adult Competency Education Kit. Basic Skills in Speaking, Math, and Reading for Employment. Part H. ACE Competency Based Job Descriptions: #25--Household Appliance Mechanic; #26--Lineworker; #27--Painter Helper, Spray; #28--Painter, Brush; #29--Carpenter Apprentice.

    San Mateo County Office of Education, Redwood City, CA. Career Preparation Centers.

    This fifth of fifteen sets of Adult Competency Education (ACE) Competency Based Job Descriptions in the ACE kit contains job descriptions for Household Appliance Mechanic; Lineworker; Painter Helper, Spray; Painter, Brush; and Carpenter Apprentice. Each begins with a fact sheet that includes this information: occupational title, D.O.T. code, ACE…

  3. The Painter in the Shadow: Gaps in Historicizing of a Woman Artist

    Tatjana Greif

    2015-09-01

    Full Text Available The article deals with the figure of the painter Henrika Šantel as it appears within national art history discourse and critics. Besides the abatement of women’s role in art history of the late 19th and early 20th centuries, the biased interpretation, contaminated with patriarchal gender ideology, is evident. With the revision of sources, biographical contextualisation of artistic production, and the inclusion of feminist theory of art practice, we aim to shed light on the historical contribution of the painter.

  4. Mind Your Manners

    Wiley, H. S.

    2010-01-01

    There has been a lot of talk in the media about the loss of courtesy in modern society. By many criteria, it seems that people in general have lost a degree of politeness. Reading some of the online comments after several recent articles in The Scientist would seem to indicate that biologists have also lost their manners. This lack of basic manners alarms me not only because of the obvious danger to our sense of community, but also because this type of behavior could damage society’s positive perception of scientists. Every time scientists (or anonymous bloggers posing as scientists) rant about the idiocy of someone who disagrees with them, our collective credibility erodes. Yes, there are a number of issues that we as scientists should be passionate about, but our objectives are best served by retaining an objective demeanor and respecting those to whom we happen to disagree.

  5. Visions of Savage Paradise : Albert Eckhout, Court Painter in Colonial Dutch Brazil

    Brienen, Rebecca Parker

    2006-01-01

    Visions of Savage Paradise is the first major book-length study of the Dutch artist Albert Eckhout to be published since 1938. This book, which draws extensively on the author's doctoral dissertation, examines the fascinating works of art produced by Eckhout while he was court painter in Dutch

  6. Carl Gawboy, Ojibwe Regional Painter. With Teacher's Guide. Native Americans of the Twentieth Century.

    Minneapolis Public Schools, MN.

    A biography for the elementary grades of Carl Gawboy (Ojibwe), an American Indian painter, includes photographs of the artist and some of his work. A teacher's guide following the bibilography contains information on watercolor painting and the Ojibwe people, learning objectives and study questions, instructions for doing a watercolor painting and…

  7. Hemispheric Specialization and Recognition Memory for Abstract and Realistic Pictures: A Comparison of Painters and Laymen

    Vogt, S.; Magnussen, S.

    2005-01-01

    Recognition memory and hemispheric specialization were assessed for abstract colour/black and white pictures of sport situations in painters and visually naive subjects using a forced choice yes/no tachistoscopic procedure. Reaction times showed a significant three-way interaction of picture type, expertise, and visual field, indicating that…

  8. Schizotypal traits in painters: Relations with intelligence, creativity and creative productivity

    Međedović Janko

    2017-01-01

    Full Text Available In the present research we explored the presence of schizotypal traits in painters. Furthermore, the relations of schizotypy and creativity-related variables (intelligence, creativity and creative productivity were analyzed. Study participants were divided into the criterion (132 students of art academy and art high school and control group (119 psychology students and members of grammar school. Two hypotheses were set: 1 schizotypal traits are more pronounced in painters than in control group; 2 schizotypy is more closely associated with the creativitylinked variables in the criterion than in control group. Schizotypy was operationalized by Disintegration construct and measured via DELTA 10 inventory. Intelligence was assessed by Advanced Progressive Matrices-18; creativity was measured by the same labeled scale from HEXACO-PI-R inventory and creative productivity was explored by a set of questions regarding the frequency of creative behavior. Results showed that Magical thinking, Enhanced awareness, Somatoform Dysregulation, Perceptual distortions and Social anhedonia were the schizotypal traits which were more pronounced in painters as compared to the control group. Factor analyses performed in each group separately revealed a latent component loaded both with schizotypal traits, creativity and creative productivity, but only in the group of painters: schizotypy and creativity were not so closely related in the control group. Thus, the study hypotheses were largely confirmed. Results provide a more detailed understanding of the relations between schizotypy and creativity.

  9. Grandes cocinas

    García de Castro, Emilio

    1957-11-01

    Full Text Available Se describen en este artículo una serie de aparatos para grandes cocinas, vistos por los autores durante un rápido viaje por Alemania. Aprovechando los datos obtenidos se analizan brevemente las necesidades de una gran cocina moderna, comentando los planos de las instalaciones en varios hoteles o instituciones de todo el mundo. La mayoría de la información.

  10. Understanding Factors that Influence Protective Glove Use among Automotive Spray Painters

    Ceballos, Diana; Reeb-Whitaker, Carolyn; Glazer, Patricia; Murphy-Robinson, Helen; Yost, Michael

    2017-01-01

    Dermal contact with isocyanate-based coatings may lead to systemic respiratory sensitization. The most common isocyanates found in sprayed automotive coatings are monomeric and oligomeric 1,6-hexamethylene diisocyanate (HDI) and isophorone diisocyanate (IPDI). Most spray painters use thin (4–5 mil) latex gloves that are not effective at preventing dermal exposures when spraying isocyanate paints. Personal interviews with collision repair industry personnel and focus groups with spray painters were held to characterize risk awareness, to examine perceptions and challenges concerning protective glove use and selection, and to generate ideas for protective glove use interventions. The most popular gloves among spray painters were thin (4–5 mil) and thick (14 mil) latex. We found that medium to thick (6–8 mil) nitrile were not always perceived as comfortable and were expected to be more expensive than thin (4–5 mil) latex gloves. Of concern is the users’ difficulty to distinguish between nitrile and latex gloves; latex gloves are now sold in different colors including blue, which has traditionally been associated with nitrile gloves. Even though spray painters were familiar with the health hazards related to working with isocyanate paints; most were not always aware that dermal exposure to isocyanates could contribute to the development of occupational asthma. There is a need for more research to identify dermal materials that are protective against sprayed automotive coatings. Automotive spray painters and their employers need to be educated in the selection and use of protective gloves, specifically on attributes such as glove material, color, and thickness. PMID:24215135

  11. Dynamic Properties of the Painter Street Overpass at Different Levels of Vibration

    Ventura, C. E.; Brincker, Rune; Andersen, P.

    2005-01-01

    This paper describes the results from a series of ambient vibration studies conducted on the Painter Street Overpass in Rio Dell, California. Painter Street is a two-span, skewed reinforced concrete bridge with two single piers near the middle and monolithic abutments, typical of bridge overpasses...... from analyses of selected strong motion records. The magnitude of the events investigated ranges from ML=4.4 to ML=6.9, which produced accelerations of up to 0.54g at the free field site, 1.3g at the abutments, and 0.86g on the deck. The results of this study indicate that the overall dynamic...... properties of the bridge are very sensitive to the level of ground shaking and that soil-structure interaction is very important for this type structural system. Although the superstructure exhibited a nearly elastic response, the motions at the abutments and base of piers were significantly different...

  12. Risk of congenital malformations among children of construction painters in Denmark

    Tougaard, Ninna Hahn; Bonde, Jens Peter; Hougaard, Karin Sørig

    2015-01-01

    OBJECTIVES: Painters' occupational exposure is classified as a group 1 carcinogen by the International Agency for Research on Cancer (IARC). Previous studies have shown increased risk of congenital malformations among children of women exposed to organic solvents and paint emissions during...... pregnancy. In Denmark, women comprise half of those enrolled in vocational paint training. We investigated the association between maternal and paternal occupational painting, respectively, and the risk of congenital malformations among children. METHODS: National register data were used to link childbirths...... diagnoses within the first 10 years of life, when stratifying by maternal age, birth year, and sex, or for paternal construction painters. CONCLUSIONS: This nationwide cohort study is reassuring with no indications of increased risk of congenital malformations among children of male or of female...

  13. Sex differences in task distribution and task exposures among Danish house painters:

    Heilskov-Hansen, Thomas; Svendsen, Susanne Wulff; Thomsen, Jane Frølund

    2014-01-01

    OBJECTIVES: Sex differences in occupational biomechanical exposures may be part of the explanation why musculoskeletal complaints and disorders tend to be more common among women than among men. We aimed to determine possible sex differences in task distribution and task-specific postures...... correction were used to evaluate sex differences. RESULTS: Statistically significant (psex differences were revealed in task proportions, but the proportions differed by less than 4%. For task exposures, no statistically significant sex differences were found. CONCLUSIONS: Only minor sex differences...... and movements of the upper extremities among Danish house painters, and to establish sex-specific task exposure matrices. METHODS: To obtain task distributions, we sent out a questionnaire to all members of the Painters' Union in Denmark (N = 9364), of whom 53% responded. Respondents reported their task...

  14. Assessment of DNA damage in car spray painters exposed to organic solvents by the high-throughput comet assay.

    Londoño-Velasco, Elizabeth; Martínez-Perafán, Fabián; Carvajal-Varona, Silvio; García-Vallejo, Felipe; Hoyos-Giraldo, Luz Stella

    2016-05-01

    Occupational exposure as a painter is associated with DNA damage and development of cancer. Comet assay has been widely adopted as a sensitive and quantitative tool for DNA damage assessment at the individual cell level in populations exposed to genotoxics. The aim of this study was to assess the application of the high-throughput comet assay, to determine the DNA damage in car spray painters. The study population included 52 car spray painters and 52 unexposed subjects. A significant increase in the %TDNA median (p  0.05). The results showed an increase in DNA breaks in car spray painters exposed to organic solvents and paints; furthermore, they demonstrated the application of high-throughput comet assay in an occupational exposure study to genotoxic agents.

  15. Study on Teaching Reformation of Contemporary Art Teaching to University Students on Corel Painter Software

    Xiong Mei Ni

    2016-01-01

    Full Text Available Contemporary art education started late in China on the basis of western teaching theories formed its own unique system, which has a great influence on Corel Painter software. This paper explores that contemporary art education is analyzed advantages and disadvantages of the influence on the development of Chinese painting, and the solutions are found out to the existing problems, summed up the reality enlightenment of that the contemporary art on the impact of education on Chinese painting development.

  16. John Bauer: Painter of a Star-Spangled Fairy-Tale World

    Sundin, M.; Roslund, C.

    Several generations of Swedish children have become acquainted with the world of fairy-tales through illustrations by the painter John Bauer in the Christmas magazine Goblins and Trolls. Next to his portrayal of grotesque but humorous trolls, his paintings of the Moon and the starry sky are among those best remembered. These pictures have inspired very many Swedes to take pleasure in the beauty of the stars and the movement of the Moon.

  17. Effect of reduced use of organic solvents on disability pension in painters.

    Järvholm, Bengt; Burdorf, Alex

    2017-11-01

    To investigate whether the decreased use of paints based on organic solvents has caused a decreased risk for neuropsychiatric disorders in painters by studying their incidence in disability pensions. The incidence of disability pension in Swedish painters who had participated in health examinations between 1971 and 1993 was studied through linkage with Swedish registers of disability pension over 1971-2010 and compared with the incidence in other construction workers as woodworkers, concrete workers and platers. When phasing out began in the 1970s, about 40% of paints were based on organic solvents and it had decreased to 4% in 1990s. The analysis was adjusted for age, time period, body mass index and smoking. The painters (n=23 065) had an increased risk of disability pension due to neurological diagnosis (n=285, relative risk (RR) 1.92, 95% CI 1.67 to 2.20) and psychiatric diagnosis (n=632, RR=1.61, 95 % CI 1.42 to 1.82). For neurological disorders there was a time trend with a continuously decreasing risk from 1980 onwards, but there was no such trend for psychiatric disorders. High exposure to organic solvents increased the risk for disability pension in neurological disorders, and the risk decreased when the use of organic solvents decreased. The painters also had an increased risk of disability pension due to psychiatric disorders, but the causes have to be further investigated. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  18. Painterly rendered portraits from photographs using a knowledge-based approach

    DiPaola, Steve

    2007-02-01

    Portrait artists using oils, acrylics or pastels use a specific but open human vision methodology to create a painterly portrait of a live sitter. When they must use a photograph as source, artists augment their process, since photographs have: different focusing - everything is in focus or focused in vertical planes; value clumping - the camera darkens the shadows and lightens the bright areas; as well as color and perspective distortion. In general, artistic methodology attempts the following: from the photograph, the painting must 'simplify, compose and leave out what's irrelevant, emphasizing what's important'. While seemingly a qualitative goal, artists use known techniques such as relying on source tone over color to indirect into a semantic color temperature model, use brush and tonal "sharpness" to create a center of interest, lost and found edges to move the viewers gaze through the image towards the center of interest as well as other techniques to filter and emphasize. Our work attempts to create a knowledge domain of the portrait painter process and incorporate this knowledge into a multi-space parameterized system that can create an array of NPR painterly rendering output by analyzing the photographic-based input which informs the semantic knowledge rules.

  19. Effects of exposure to ethylene glycol ethers on shipyard painters: II. Male reproduction.

    Welch, L S; Schrader, S M; Turner, T W; Cullen, M R

    1988-01-01

    To determine whether 2-ethoxyethanol (2-EE) and 2-methoxyethanol (2-ME) affected the reproductive potential of exposed men, we examined the semen of 73 painters and 40 controls who work in a large shipyard. An industrial hygiene survey was performed to characterize the work environment. The men supplied information on demographic characteristics, medical conditions, personal habits, and reproductive history; underwent a physical examination; and provided a semen sample. Semen samples were analyzed for pH, volume, turbidity, liquidity, viability by stain exclusion and hypo-osmotic stress, sperm density and count per ejaculate, motility using a videotape technique, morphology, and morphometry. Serum was analyzed for testosterone, FSH, and LH. The industrial hygiene survey revealed that the painters were exposed to 2-EE at a time-weighted average (TWA) of 0-80.5 mg/m3 with a mean of 9.9 mg/m3, and to 2-ME at a TWA of 0-17.7 mg/m3 with a mean of 2.6 mg/m3. Painters had an increased prevalence of oligospermia and azoospermia and an increased odds ratio for a lower sperm count per ejaculate, while smoking was controlled. This finding is consistent with prior animal studies and with one human study. Potential biases and confounding of the data are discussed.

  20. Speech Mannerisms: Games Clients Play

    Morgan, Lewis B.

    1978-01-01

    This article focuses on speech mannerisms often employed by clients in a helping relationship. Eight mannerisms are presented and discussed, as well as possible interpretations. Suggestions are given to help counselors respond to them. (Author)

  1. María Baldomera Fuentes Segura, a painter and your destinity

    María Teresa Fleitas-Monnar

    2016-05-01

    Full Text Available This paper deals with the artist Baldomera Fuentes Segura from Santiago de Cuba, today recognized as the first Cuban painter. Her figure as a creator is addressed in a social, cultural and personal context which makes it an exceptional woman of the nineteenth century in Santiago de Cuba. Her miniatures, making in waterpaintig on ivory and an oil painting on canvas, religious are valued. They are preserved in the Emilio Bacardi Moreau Museum of this city, as part of a moment of aesthetic transition occurred between the late eighteenth and early nineteenth centuries in Latin America, when the neoclassic was the principal style on the fine arts.

  2. Foot deformities in Renaissance paintings. A mystery of symbolism, artistic licence, illusion and true representation in five renowned Renaissance painters.

    Lazzeri, D; Castello, M F; Grassetti, L; Dashti, T; Zhang, Y X; Persichetti, P

    2015-01-01

    Although Renaissance artists were skilled in representing normal anatomy, a close look at some paintings reveals anatomical variations in the depiction of the feet of human figures. A systematic review has identified 25 paintings by five artists in which the presumptive medico-artistic diagnosis of congenital or acquired foot deformity seems to be varyingly present. The connection between these five painters and what factors have influenced artists' style in the depiction of such deformities is discussed. The possible iconography and medical-historical meaning of such variations, as well as the possibility of artistic licence and real representation that drove the painters to depict these deformities, is explored and debated.

  3. Hugh Ramsay’s Self-Portrait: Reflections on a Spanish Master Painter

    Jenny Beatriz Quijano Martínez

    2015-01-01

    Full Text Available The interest in European masters from the past was a phenomenon related to the development of the artistic careers of many artists in Australia at the end of the nineteenth and beginning of the twentieth century. More than that, the copying or emulation of great works of art was seen to be a necessary part of an artist’s training1. This paper looks at Hugh Ramsay and his fascination with the painting Las Meninas (1656 by Velázquez as part of a larger study into understanding how the Spanish in uence was re ected in Australian art. Ramsay introduced elements from Las Meninas into his Portrait of the artist standing before easel, which took him to personify the role of the painter as Velázquez.

  4. Low-temperature thermochronology of the Mt Painter Province, South Australia

    Mitchell, M.M.; Kohn, B.P.; O'Sullivan, P.B.; Hartley, M.J.; University of Florida, FL

    2002-01-01

    Apatite fission track results are reported for 26 outcrop samples from the Mt Painter Inlier, Mt Babbage Inlier and adjacent Neoproterozoic rocks of the northwestern Curnamona Craton of South Australia. Forward modelling of the data indicates that the province experienced variable regional cooling from temperatures >110deg C during the Late Palaeozoic (Late Carboniferous to Early Permian). The timing of this cooling is similar to that previously reported from elsewhere in the Adelaide Fold Belt and the Curnamona Craton, suggesting that the entire region underwent extensive Late Palaeozoic cooling most likely related to the waning stages of the Alice Springs or Kanimblan Orogenies. Results from the Paralana Fault Zone indicate that the eastern margin of the Mt Painter Inlier experienced a second episode of cooling (∼40-60deg C) during the Paleocene to Eocene. The entire region also experienced significant cooling (less than ∼40deg C) during the Late Cretaceous to Palaeogene in response to unroofing and/or a decrease in geothermal gradient. Regional cooling/erosion during this time is supported by: geomorphological and geophysical evidence indicating Tertiary exhumation of at least 1 km; Eocene sedimentation initiated in basins adjacent to the Flinders and Mt Lofty Ranges sections of the Adelaide Fold Belt; and Late Cretaceous - Early Tertiary cooling previously reported from apatite fission track studies in the Willyama Inliers and the southern Adelaide Fold Belt. Late Cretaceous to Palaeogene cooling is probably related to a change in stress field propagated throughout the Australian Plate, and driven by the initiation of sea-floor spreading in the Tasman Sea in the Late Cretaceous and the Eocene global plate reorganisation. Copyright (2002) Geological Society of Australia

  5. The creation of Camaldolese painter Father Vincent of Subbiaco in light of recent studies

    Adam Małkiewicz

    2005-12-01

    Full Text Available A Camaldolese painter, Father Venanzio da Subiaco (around 1570-1659, was active in Poland from 1624 to 1632, when he stayed in the hermitages at Bielany, near Cracow, and at Rytwiany. His name has been familiar to Polish scholars since 1871 (L. Zarewicz, and in 1952 his first brief monograph was written by Witold Urbanowicz, devoted, however, merely to his achievements in Poland. The monograph was later supplemented and verified by other researchers (J. Z. Łoziński and T. Przypkowski, W Kret., A. Ryszkiewicz, A. Małkiewicz. Venanzio’s work accomplished in Italy remained iong unknown. It was only in 1995 that Lucilia Conigliello organized an exhibition in Poppi featuring 14 paintings by Venanty, which she discovered in a Camaldolese hermitage and coenobium in Camaldoli. In the catalogue she discussed his 34 Italian works. In a catalogue of another exhibition of the Baroque art in Castentino (Poppi 2001, Conigliello included a short monograph of the painter, presenting his art both from the Italian and Polish period. The aim of this paper is to present a critical overview of the present state of research on Venanzio. His art created prior to joining the Order in 1618 remains unknown. As a Camaldolese monk he worked almost entirely for the congregation and sporadically for people connected with it, which limited the iconography of his paintings to religious themes. The artist’s preserved works include three sets of mural painitng (Monte Rua, near Padua, Bielany, Rytwiany and 50 oil paintings, 10 of which are in Polish monasteries. Their style bears influence of Caravaggio and is characterized by certain conservatism. The artist was also inspired by the paintings of great Renaissance masters, especially Titian, through the mediation of graphics. An important contribution of Venanzio was creating an iconographical canon of the Camaldolese church painting decoration, which was accomplished by the artist during his stay in Poland and

  6. The Drawings of the Florentine Painters: From Print Catalog to Linked Open Data

    Lukas Klic,

    2017-10-01

    Full Text Available The Drawings of The Florentine Painters project created the first online database of Florentine Renaissance drawings by applying Linked Open Data (LOD techniques to a foundational text of the same name, first published by Bernard Berenson in 1903 (revised and expanded editions, 1938 and 1961. The goal was to make Berenson’s catalog information—still an essential information resource today—available in a machine-readable format, allowing researchers to access the source content through open data services. This paper provides a technical overview of the methods and processes applied in the conversion of Berenson’s catalog to LOD using the CIDOC-CRM ontology; it also discusses the different phases of the project, focusing on the challenges and issues of data transformation and publishing. The project was funded by the Samuel H. Kress Foundation and organized by Villa I Tatti, The Harvard University Center for Italian Renaissance Studies. Catalog: http://florentinedrawings.itatti.harvard.edu Data Endpoint: http://data.itatti.harvard.edu

  7. Solvent exposure and related work practices amongst apprentice spray painters in automotive body repair workshops.

    Winder, C; Turner, P J

    1992-08-01

    As part of a multidisciplinary study into the health effects of solvents, workplace assessments and airborne solvent vapour monitoring was conducted in 46 spray painting workshops in the Sydney metropolitan area. Breathing-zone samples were taken from 50 apprentices and 14 experienced spray painters. An interview schedule was developed to obtain information about the use of acrylic or two-pack paint systems, the use of engineering controls, the use of personal protective equipment and the availability of material safety data sheets. Contaminants typical of the chemical products used in this industry were encountered (aromatic hydrocarbons, C5-C7 aliphatic hydrocarbons, ketones, esters). The results of airborne solvent monitoring indicate a total solvent exposure in the range 1-99% of a combined Worksafe Australia exposure standard, with a mean of 19%. Solvent exposure was highest when spraying acrylic paint in the open workshop and lowest when spraying two pack paint in a spray booth. Much the same personal protective equipment was available in all workshops, but wide variation in its use was observed. Material safety data sheets were not observed in any of the workshops.

  8. VennPainter: A Tool for the Comparison and Identification of Candidate Genes Based on Venn Diagrams.

    Guoliang Lin

    Full Text Available VennPainter is a program for depicting unique and shared sets of genes lists and generating Venn diagrams, by using the Qt C++ framework. The software produces Classic Venn, Edwards' Venn and Nested Venn diagrams and allows for eight sets in a graph mode and 31 sets in data processing mode only. In comparison, previous programs produce Classic Venn and Edwards' Venn diagrams and allow for a maximum of six sets. The software incorporates user-friendly features and works in Windows, Linux and Mac OS. Its graphical interface does not require a user to have programing skills. Users can modify diagram content for up to eight datasets because of the Scalable Vector Graphics output. VennPainter can provide output results in vertical, horizontal and matrix formats, which facilitates sharing datasets as required for further identification of candidate genes. Users can obtain gene lists from shared sets by clicking the numbers on the diagram. Thus, VennPainter is an easy-to-use, highly efficient, cross-platform and powerful program that provides a more comprehensive tool for identifying candidate genes and visualizing the relationships among genes or gene families in comparative analysis.

  9. Buried Messages, Hidden Meanings: Speech Mannerisms Revisited.

    Morgan, Lewis B.

    1988-01-01

    Introduces counselors to 10 commonly used mannerisms of speech and the part that each mannerism plays in the communication process, especially in the counseling context. Offers suggestions on how to respond to these speech mannerisms in a straightforward and effective manner. (Author)

  10. Grand Hotel prijutil hudozhnikov

    2004-01-01

    Raadioajakirjanik Lea Veelmaa lindistas "Kunstikanali" 2004. a. esimese saate Grand Hotel Viljandis. Saatekülaliseks oli maalikunstnik Andres Tolts. Toltsi kaheksa akrüülmaali on eksponeeritud hotelli fuajees ja restoranis

  11. Grand Mal Seizure

    ... grand mal seizures include: A family history of seizure disorders Any injury to the brain from trauma, a ... the risk of birth defects. If you have epilepsy and plan to become pregnant, work with your ...

  12. Review of David Brooks and Darren Jorgenson, The Wanarn Painters of Place and Time: Old Age Travels in the Tjukurrpa

    Una Rey

    2018-01-01

    The Aboriginal painting movement has long been characterised by ‘remote stars’ whose seniority connotes the last generation to embody the full lexicon of pre-contact experience of language, law (tjukurrpa) and Country. Witness, for example, Emily Kame Kngwarreye, whose career—launched in her eighties—was all ‘late’; the taciturn old men guiding the middle-aged painters at Papunya in the early 1970s; or the last Nyikina speaker, Loongkoonan, who started painting in her nineties and is now brus...

  13. Effects of radium-226 on bone from a radium dial painter at 12 years and 55 years after ingestion

    Henning, C.B.; Lloyd, E.L.

    1982-01-01

    Samples of bone from two different sites in a female former radium dial painter, collected 43 years apart, were examined with the electron microscope. The results show further evidence for the presence of a fibrotic layer of tissue covering bone mineral which separates the bone lining cells from the source of the radioactive deposits in bone mineral. This work further confirms our contention that many of the cells at risk for the production of bone tumors probably lie outside the single bone lining cell layer which characteristically lies about 1 to 2 μm away from bone mineral in normal control bone

  14. Standard practice for qualification of journeyman painters for application of coatings to concrete surfaces of safety-related areas in nuclear facilities

    Anon.

    1984-01-01

    This practice provides a standard qualifying method for journeyman painters to verify their proficiency and ability to attain the required quality for application of specified coatings to concrete surfaces in safety-related areas in a nuclear facility. Variations or simplifications of the practice set forth herein may be appropriate for special coating work such as maintenance. It is not the intent of this practice to mandate a singular basis for all qualifications. Evaluation of the journeyman painter being qualified in accordance with this practice, shall be by qualified agents as specified in 4.1. Reports shall be prepared as specified in Section 5, and qualification as specified in Section 6. It is the intent of this practice to judge only the ability of the journeyman painter to apply specified coatings with the proper tools and equipment

  15. Standard practice for qualification of journeyman painters for application of coatings to steel surfaces of safety-related areas in nuclear facilities

    Anon.

    1984-01-01

    This practice provides a standard qualifying method for journeyman painters to verify their proficiency and ability to attain the required quality for application of specified coatings to steel surfaces in safety-related areas in a nuclear facility. Variations or simplifications of the practice set forth herein may be appropriate for special coating work such as maintenance or qualifications of equipment suppliers shop personnel. It is not the intent of this practice to mandate a singular basis for all qualifications. Evaluation of the journeyman painter being qualified in accordance with this practice, shall be by qualified agents as specified in 4.1. Reports shall be prepared as specified in Section 5, and certification as specified in Section 6. It is the intent of this practice to judge only the ability of the journeyman painter to apply specified coatings with the proper tools and equipment. This standard may involve hazardous materials, operations, and equipment

  16. Democracy and "Grand" Corruption.

    Rose-Ackerman, Susan

    1996-01-01

    Defines "grand" corruption as that occurring at the higher levels of a political system and involving large sums of money. Discusses the impact and incentives for this level of corruption as well as various government responses. Identifies multinational corporations as the major malefactors. (MJP)

  17. The GRANDE detector

    Adams, A.; Bond, R.; Coleman, L.; Rollefson, A.; Wold, D.; Bratton, C.B.; Gurr, H.; Kropp, W.; Nelson, M.; Price, L.R.; Reines, F.; Schultz, J.; Sobel, H.; Svoboda, R.; Yodh, G.; Burnett, T.; Chaloupka, V.; Wilkes, R.J.; Cherry, M.; Ellison, S.B.; Guzik, T.G.; Wefel, J.; Gaidos, J.; Loeffler, F.; Sembroski, G.; Wilson, C.; Goodman, J.; Haines, T.J.; Kielczewska, D.; Lane, C.; Steinberg, R.; Lieber, M.; Nagle, D.; Potter, M.; Tripp, R.

    1990-01-01

    In this paper we present a detector facility which meets the requirements outlined above for a next-generation instrument. GRANDE (Gamma Ray and Neutrino DEtector) is an imaging, water Cerenkov detector, which combines in one facility an extensive air shower array and a high-energy neutrino detector. (orig.)

  18. Triggering the GRANDE array

    Wilson, C.L.; Bratton, C.B.; Gurr, J.; Kropp, W.; Nelson, M.; Sobel, H.; Svoboda, R.; Yodh, G.; Burnett, T.; Chaloupka, V.; Wilkes, R.J.; Cherry, M.; Ellison, S.B.; Guzik, T.G.; Wefel, J.; Gaidos, J.; Loeffler, F.; Sembroski, G.; Goodman, J.; Haines, T.J.; Kielczewska, D.; Lane, C.; Steinberg, R.; Lieber, M.; Nagle, D.; Potter, M.; Tripp, R.

    1990-01-01

    A brief description of the Gamma Ray And Neutrino Detector Experiment (GRANDE) is presented. The detector elements and electronics are described. The trigger logic for the array is then examined. The triggers for the Gamma Ray and the Neutrino portions of the array are treated separately. (orig.)

  19. Grand-Bassam

    Geo

    l'estuaire du fleuve Comoé (Grand-Bassam, Côte d'Ivoire). Kouassi Laurent ADOPO1*, Apie Colette AKOBE1, Etche Mireille AMANI2,. Sylvain MONDE3 et Kouamé AKA3. (1)Laboratoire de Géologie Marine, Sédimentologie et Environnement, Centre de Recherche en Ecologie,. Université Felix Houphouet Boigny Abidjan, ...

  20. Kant, Xunzi and the Artificiality of Manners

    Anja BERNINGER

    2017-01-01

    Full Text Available Both Chinese and Western philosophers have argued for the ethical importance of manners. Their approaches are sometimes criticized on the grounds that manners are artificial. I compare Xunzi’s and Kant’s responses to this claim, and discuss the relevance of both positions for the development of a theory of manners. I show that there is no single artificiality claim, but rather four different claims: the claim that polite behavior lacks spontaneity, the claim that it is insincere, the claim that it goes against human nature, and the claim that it is arbitrary. While Kant is mainly concerned with the insincerity claim, Xunzi focusses on the claim that manners are arbitrary rules. Because of their different understandings of the function of manners both authors only provide a partial answer to the artificiality claim. To arrive at a full account of manners both perspectives must be combined.

  1. Grand unified theories

    Langacker, P.

    1981-01-01

    In this talk I discuss the present status of these theories and of their observational and experimental implications. In section II, I briefly review the standard SU 3 sup(c) x SU 2 x U 1 model of the strong and electroweak interactions. Although phenomenologically successful, the standard model leaves many questions unanswered. Some of these questions are addressed by grand unified theories, which are defined and discussed in Section III. The Georgi-Glashow SU 5 model is described, as are theories based on larger groups such as SO 10 , E 6 , or SO 16 . It is emphasized that there are many possible grand unified theories and that it is an experimental problem not only to test the basic ideas but to discriminate between models. (orig./HSI)

  2. Asymptotically safe grand unification

    Bajc, Borut [J. Stefan Institute,1000 Ljubljana (Slovenia); Sannino, Francesco [CP-Origins & the Danish IAS, University of Southern Denmark,Campusvej 55, DK-5230 Odense M (Denmark); Université de Lyon, France, Université Lyon 1, CNRS/IN2P3, UMR5822 IPNL,F-69622 Villeurbanne Cedex (France)

    2016-12-28

    Phenomenologically appealing supersymmetric grand unified theories have large gauge representations and thus are not asymptotically free. Their ultraviolet validity is limited by the appearance of a Landau pole well before the Planck scale. One could hope that these theories save themselves, before the inclusion of gravity, by generating an interacting ultraviolet fixed point, similar to the one recently discovered in non-supersymmetric gauge-Yukawa theories. Employing a-maximization, a-theorem, unitarity bounds, as well as positivity of other central charges we nonperturbatively rule out this possibility for a broad class of prime candidates of phenomenologically relevant supersymmetric grand unified theories. We also uncover candidates passing these tests, which have either exotic matter or contain one field decoupled from the superpotential. The latter class of theories contains a model with the minimal matter content required by phenomenology.

  3. LA GRANDE DESCENTE

    The first endcap disc of CMS being lowered slowly and carefully 100 m underground into the experimental cavern. The disc is one of 15 large pieces to make the grand descent.  The uniquely shaped slice, 16 m high, about 50 cm thick weighs 400 tonnes. The two HF that were lowered earlier in November can also be seen in the foreground and background.  

  4. Dermal, inhalation, and internal exposure to 1,6-HDI and its oligomers in car body repair shop workers and industrial spray painters

    Pronk, A.; Yu, F.; Vlaanderen, J.; Tielemans, E.; Preller, L.; Bobeldijk, I.; Deddens, J.A.; Latza, U.; Baur, X.; Heederik, D.

    2006-01-01

    Objectives: To study inhalation and dermal exposure to hexamethylene diisocyanate (HDI) and its oligomers as well as personal protection equipment (PPE) use during task performance in conjunction with urinary hexamethylene diamine (HDA) in car body repair shop workers and industrial spray painters.

  5. Evidence for an unorthodox firing sequence employed by the Berlin Painter : deciphering ancient ceramic firing conditions through high-resolution material characterization and replication

    Cianchetta, I.; Trentelman, K.; Maish, J.; Saunders, D.; Foran, B.; Walton, M.; Sciau, Ph.; Wang, T.; Pouyet, E.; Cotte, M.; Meirer, F.; Liu, Y.; Pianetta, P.; Mehta, A.

    2015-01-01

    XANES spectroscopy was used to complement the results previously obtained with Raman spectroscopy by the same group to determine the firing conditions used in the production of a single vessel painted by the Berlin Painter in the 5th century B.C. The vessel, part of the collection of the J. Paul

  6. Exposure Assessment Suggests Exposure to Lung Cancer Carcinogens in a Painter Working in an Automobile Bumper Shop

    Boowook Kim

    2013-12-01

    Full Text Available A 46-year-old man who had worked as a bumper spray painter in an automobile body shop for 15 years developed lung cancer. The patient was a nonsmoker with no family history of lung cancer. To determine whether the cancer was related to his work environment, we assessed the level of exposure to carcinogens during spray painting, sanding, and heat treatment. The results showed that spray painting with yellow paint increased the concentration of hexavalent chromium in the air to as much as 118.33 μg/m3. Analysis of the paint bulk materials showed that hexavalent chromium was mostly found in the form of lead chromate. Interestingly, strontium chromate was also detected, and the concentration of strontium chromate increased in line with the brightness of the yellow color. Some paints contained about 1% crystalline silica in the form of quartz.

  7. Grande do Sul, Brasil

    Denis Alcides-Rezende

    2008-01-01

    Full Text Available The objective of this work is to analyse the integration of information systems and information technology resources in the municipal planning of 14 small cities of Rio Grande do Sul (Brazil. The research methodology consisted of a multiple case study together with a convenient non-probabilistic sample chosen through a research protocol. The results demonstrate the difficulties of these cities to organise the municipal data as well as their struggle for accessibility of information and planning for management and control.

  8. Aplikasi Pembelajaran Table Manners Berbasis Multimedia

    Yosanny, Agustinna; Pradipta, Albert; Viles, Dody; Pensen, Pensen

    2011-01-01

    Table manners adalah aturan-aturan pokok yang berlaku di meja makan. Aturan ini biasanya diterapkan padajamuan makan resmi. Penelitian ini bertujuan untuk merancang dan mengembangkan suatu aplikasipembelajaran tentang table manners untuk memudahkan dalam mempelajari aturan-aturan yang perlu diketahuidalam jamuan makan resmi, meliputi etika sebelum dan saat proses menyantap makanan, serta penggunaanalat-alat makan. Metode penelitian yang digunakan adalah metode Interactive Multimedia System De...

  9. Cassini's Grand Finale Overview

    Spilker, L. J.

    2017-12-01

    After 13 years in orbit, the Cassini-Huygens Mission to Saturn ended in a science-rich blaze of glory. Cassini sent back its final bits of unique science data on September 15, 2017, as it plunged into Saturn's atmosphere, vaporizing and satisfying planetary protection requirements. Cassini's final phase covered roughly ten months and ended with the first time exploration of the region between the rings and planet. In late 2016 Cassini transitioned to a series of 20 Ring Grazing orbits with peripases just outside Saturn's F ring, providing close flybys of tiny ring moons, including Pan, Daphnis and Atlas, and high-resolution views of Saturn's A and F rings. A final Titan flyby in late April 2017 propelled Cassini across Saturn's main rings and into its Grand Finale orbits. Comprised of 22 orbits, Cassini repeatedly dove between Saturn's innermost rings and upper atmosphere to answer fundamental questions unattainable earlier in the mission. The last orbit turned the spacecraft into the first Saturn atmosphere probe. The Grand Finale orbits provided highest resolution observations of both the rings and Saturn, and in-situ sampling of the ring particle composition, Saturn's atmosphere, plasma, and innermost radiation belts. The gravitational field was measured to unprecedented accuracy, providing information on the interior structure of the planet, winds in the deeper atmosphere, and mass of the rings. The magnetic field provided insight into the physical nature of the magnetic dynamo and structure of the internal magnetic field. The ion and neutral mass spectrometer sampled the upper atmosphere for molecules that escape the atmosphere in addition to molecules originating from the rings. The cosmic dust analyzer directly sampled the composition from different parts of the main rings for the first time. Fields and particles instruments directly measured the plasma environment between the rings and planet. Science highlights and new mysteries collected in the Grand

  10. Grand unification and supergravity

    Nanopoulos, D.V.

    Grand Unified Theories (GUTs) are very successful, but they suffer from fine-tuning or hierarchy problems. It seems that more symmetry beyond the gauge symmetry is needed and indeed supersymmetric GUTs may provide the correct framework in solving the hierarchy problems. These are reviewed. From the results discussed, it is seen that for the first time in particle physics, gravity seems to play a dominant role. It may be responsible for GUT breaking, SU(2) x U(1) breaking, fermion masses, proton decay and a consistent cosmological picture. Supergravity seems to offer a consistent, effective theory for energies below the Planck scale to N=1 local SUSY but also, in the context of N=8 extended supergravity with a dynamically realized SU(8), there may be a consistent fundamental unified theory of all interactions. (U.K.)

  11. Grand unification: status report

    Georgi, H.

    1983-01-01

    Grand unification is reviewed with regard to the flavor puzzle and the hierarchy puzzle. Progress in CP and the PQWWKDFS axion is reviewed. The neutrino mass and B-L research, the understanding and assimilation of the language of effective theories (which divide the momentum scale up into regions), with focus on the models, are surveyed. Various unified models are organized according to whether they address the hierarchy puzzle or the flavor puzzle. SU(5), SO(10), E6, and Higgs are considered simple and explicit models. Global symmetry addresses hierarchy puzzle, but the rules are unclear. In SO (18), with regard to hierarchy, perturbation theory breaks down. SO (14) fails for hierarchy because of GIM, b and t problems. Supersymmetry and technicolor with regard to flavor puzzle are questioned. The CP solution of ETC and Composite C models (addressing both flavor and hierarchy) is a minus. Composite A model has no evident virtues, and the basic idea of ETC model needs checking

  12. Grand unified theories. Pt. 2

    Ellis, J.

    1982-01-01

    The author gives an introduction to the construction of grand unified theories on the base of the SU(3)xSU(2)xU(1) model of the strong, weak, and electromagnetic interactions. Especially he discusses the proton decay, neutrino masses and oscillations, and cosmological implications in connection with grand unified theories. (orig./HSI)

  13. La importancia de ser grande

    Baisre, J. A.

    2007-01-01

    Se responde a las preguntas ¿por qué los mamíferos marinos son los animales más grandes del planeta?, ¿Por qué los peces no pueden ser más grandes?. Éstas y otras interrogantes son respondidas de forma sencilla y clara.

  14. Contribution to the Catalogue of the painter and illustrator John Vanderbank: Six new Oils with Scenes of The Quixote in the Museum of Pontevedra

    María Ángeles Tilve Jar

    2014-12-01

    Full Text Available In the Museum of Pontevedra stands out a set of six pictures of small format that narrate scenes of the Quixote. Realized in oil on table, they are works of the Englishman painter and illustrator John Vanderbank (1694-1739. In those pictures he adapts some of the prints that himself designed to illustrate the edition of luxury of Miguel de Cervantes who, promoted by Lord Carteret and printed by the Tonson brothers, was realized in London in 1738.

  15. Sex differences in task distribution and task exposures among Danish house painters: an observational study combining questionnaire data with biomechanical measurements.

    Thomas Heilskov-Hansen

    Full Text Available OBJECTIVES: Sex differences in occupational biomechanical exposures may be part of the explanation why musculoskeletal complaints and disorders tend to be more common among women than among men. We aimed to determine possible sex differences in task distribution and task-specific postures and movements of the upper extremities among Danish house painters, and to establish sex-specific task exposure matrices. METHODS: To obtain task distributions, we sent out a questionnaire to all members of the Painters' Union in Denmark (N = 9364, of whom 53% responded. Respondents reported their task distributions in a typical week. To obtain task exposures, postures and movements were measured in 25 male and 25 female house painters for one whole working day per person. We used goniometers on the wrists, and inclinometers on the forehead and the upper arms. Participants filled in a logbook allowing task-specific exposures to be identified. Percentiles and % time with non-neutral postures were used to characterise postures. Velocity, range of motion, repetitiveness, and variation were used as measures of movement. Cochran-Mantel-Haenszel statistics and unpaired double-sided t-tests with post-hoc Bonferroni correction were used to evaluate sex differences. RESULTS: Statistically significant (p<0.05 sex differences were revealed in task proportions, but the proportions differed by less than 4%. For task exposures, no statistically significant sex differences were found. CONCLUSIONS: Only minor sex differences were found in task distribution and task exposures regarding postures and movements among Danish house painters. Sex-specific task exposure matrices were established.

  16. CERN Library and Art@CMS present Artist and Painter Xavier Cortada and CMS Physicist Pete Markowitz

    CERN Library

    2013-01-01

    Xavier Cortada is an American artist and painter, and an artist in residence at Florida International University (FIU) College of Architecture and the Arts who also specializes in participatory art projects. His work includes art installations at the Earth’s poles to generate awareness about climate change, child welfare murals in Bolivia and peace murals in Cyprus. Xavier will be in conversation with CMS physicist Pete Markowitz, also from FIU, to discuss the participatory art piece which they developed together. The piece will be showcased in the CMS detector hall on Thursday 11 April during the experiment’s conference week. The piece promises to "engage 300 scientists from around the world in a performance art piece that transforms them into the very subatomic particles they research". It is the first piece by Art@CMS, a new project inspired by the Arts@CERN programme. Discover more about how this new piece was developed and more about Xavier’s ...

  17. The Travelogue Lacroma, Work of Stephanie, Crown Princess of Austria, and Anton Perko, Seascape Painter at the Court

    Sanja Žaja Vrbica

    2016-01-01

    Full Text Available Among the numerous travelogues describing southern Dalmatia, Dubrovnik, and its surroundings, the booklet called Lacroma merits special attention. Its author was the widowed Crown Princess Stephanie (1864-1945 and the illustrations were provided by Anton Perko, seascape painter at the court and the former governor of Lokrum. The first edition was published in 1892 in German, followed by an Italian one five years later. This article focuses on the first, German edition. Painter Anton Perko (1833-1905 stayed on the island of Lokrum from January 1879 until the beginning of 1881, with minor absences. The following year, he spent the entire winter on the island, and when the princely couple moved to Vienna, he also moved there in 1883. After the Mayerling drama, when Rudolf and his young mistress Marie Vetsera were found dead under mysterious circumstances, Perko’s life changed as well, yet he remained in the service of the widowed princess until 1896, when he retired. Anton Perko did not write an autobiography, but his important position in the royal household is evident from the fact that Stephanie and her daughter took care of his widow after his death in 1905. In 1892, a volume on Dalmatia was published as part of the complex work Die österreichisch-ungarische Monarchie in Wort und Bild, initiated by Prince Rudolf and continued by his widow Stephanie, which must have also inspired her to write a separate book on Lokrum with its rich historical, cultural, and natural heritage. Her description of Lokrum is intended for future tourists, potential visitors from the north, and introduces the reader to this insular Arcadia with descriptions of its position in southern Dalmatia and Dubrovnik, after which she turns to the history of Lokrum and its monuments, with reference to two written sources: the Apendius chronicle and the Memorie storiche sull’isola Lacroma, published in Vienna in 1861. Illustrations by Anton Perko are completely subjected to

  18. Supersymmetric grand unified theories and cosmology

    Lazarides, G.; Shafi, Q.

    1983-01-01

    By examining the behavior of supersymmetric grand unified theories (GUT's) in the very early universe we find two classes of realistic models. In one of them supersymmetry is broken at or near superheavy GUT scale. The cosmological implications of such models are expected to be similar to those of nonsupersymmetric GUT's. In the second class of models, the superheavy GUT scale is related to the supersymmetry-breaking scale in the manner of Witten. Two types of cosmological scenarios appear possible in this case, either with or without an intermediate (new) inflationary phase. They can be experimentally distinguished, since the former predicts an absence and the latter an observable number density of superheavy monopoles. A mechanism for generating baryon asymmetry in such models is pointed out

  19. Grand slam on cancer.

    Gartrell, Nanette

    2014-01-01

    A winner of 59 Grand Slam championships including a record 9 Wimbledon singles titles, Martina Navratilova is the most successful woman tennis player of the modern era. Martina was inducted into the International Tennis Hall of Fame, named "Tour Player of the Year" seven times by the Women's Tennis Association, declared "Female Athlete of the Year" by the Associated Press, and ranked one of the "Top Forty Athletes of All-Time" by Sports Illustrated. Equally accomplished off the court, Martina is an author, philanthropist, TV commentator, and activist who has dedicated her life to educating people about prejudice and stereotypes. After coming out as a lesbian in 1981, Martina became a tireless advocate of equal rights for lesbian, gay, bisexual, and transgender (LGBT) people, and she has contributed generously to the LGBT community. Martina is the author of seven books, including most recently Shape Your Self: My 6-Step Diet and Fitness Plan to Achieve the Best Shape of your Life, an inspiring guide to healthy living and personal fitness. Martina was diagnosed with breast cancer in 2010.

  20. Magnetic spectrometer Grand Raiden

    Fujiwara, M.; Akimune, H.; Daito, I.; Fujimura, H.; Fujita, Y.; Hatanaka, K.; Ikegami, H.; Katayama, I.; Nagayama, K.; Matsuoka, N.; Morinobu, S.; Noro, T.; Yoshimura, M.; Sakaguchi, H.; Sakemi, Y.; Tamii, A.; Yosoi, M.

    1999-01-01

    A high-resolution magnetic spectrometer called 'Grand Raiden' is operated at the RCNP ring cyclotron facility in Osaka for nuclear physics studies at intermediate energies. This magnetic spectrometer has excellent ion-optical properties. In the design of the spectrometer, the second-order dispersion matching condition has been taken into account, and almost all the aberration terms such as (x vertical bar θ 3 ), (x vertical bar θφ 2 ), (x vertical bar θ 2 δ) and (x vertical bar θδ 2 ) in a third-order matrix calculation are optimized. A large magnetic rigidity of the spectrometer (K = 1400 MeV) gives a great advantage to measure the charge-exchange ( 3 He, t) reactions at 450 MeV. The ability of the high-resolution measurement has been demonstrated. Various coincidence measurements are performed to study the nuclear structures of highly excited states through decay properties of nuclear levels following nuclear reactions at intermediate energies

  1. Clinical physiology grand rounds.

    Richards, Jeremy; Schwartzstein, Richard; Irish, Julie; Almeida, Jacqueline; Roberts, David

    2013-04-01

    Clinical Physiology Grand Rounds (CPGR) is an interactive, case-based conference for medical students designed to: (1) integrate preclinical and clinical learning; (2) promote inductive clinical reasoning; and (3) emphasise students as peer teachers. CPGR specifically encourages mixed learning level student interactions and emphasises the use of concept mapping. We describe the theoretical basis and logistical considerations for an interactive, integrative, mixed-learner environment such as CPGR. In addition, we report qualitative data regarding students' attitudes towards and perceptions of CPGR. Medical students from first to fourth year participate in a monthly, interactive conference. The CPGR was designed to bridge gaps and reinforce linkages between basic science and clinical concepts, and to incorporate interactive vertical integration between preclinical and clinical students. Medical education and content experts use Socratic, interactive teaching methods to develop real-time concept maps to emphasise the presence and importance of linkages across curricula. Student focus groups were held to assess attitudes towards and perceptions of the mixed-learner environment and concept maps in CPGR. Qualitative analyses of focus group transcripts were performed to develop themes and codes describing the students' impressions of CPGR. CPGR is a case-based, interactive conference designed to help students gain an increased appreciation of linkages between basic science and clinical medicine concepts, and an increased awareness of clinical reasoning thought processes. Success is dependent upon explicit attention being given to goals for students' integrated learning. © Blackwell Publishing Ltd 2013.

  2. SOEKARNO: HIS MANNERISM AND METHOD OF COMMUNICATION

    Justin Wejak

    2000-01-01

    The main purpose of this article is to discuss Soekarno's mannerism and method of communication. Certain aspects such as Soekarno's use of language in his speeches are highlighted here in order to provide some basic understanding of Soekarno - both as a person and a political leader of the nation. The article aims at stimulating further discussions concerning this very well known leader. This article also examines Soeharto's style of speech for a comparison.

  3. SOEKARNO: HIS MANNERISM AND METHOD OF COMMUNICATION

    Justin Wejak

    2000-01-01

    Full Text Available The main purpose of this article is to discuss Soekarno's mannerism and method of communication. Certain aspects such as Soekarno's use of language in his speeches are highlighted here in order to provide some basic understanding of Soekarno - both as a person and a political leader of the nation. The article aims at stimulating further discussions concerning this very well known leader. This article also examines Soeharto's style of speech for a comparison.

  4. High-heat geodynamic setting during the Palaeozoic evolution of the Mount Painter Province, SA, Australia: evidence from combined field structural geology and potential-field inversions

    Armit, R. J.; Ailleres, L.; Betts, P. G.; Schaefer, B. F.; Blaikie, T. N.

    2014-10-01

    A method for subsurface recognition of blind geological bodies is presented using combined surface constraints and 3-D structural modelling that incorporates constraints from detailed mapping, and potential-field inversion modelling. This method is applied to the Mount Painter Province and demonstrates that addition of low density material is required to reconcile the gravity signature of the region. This method may be an effective way to construct 3-D models in regions of excellent structural control, and can be used to assess the validity of surface structures with 3-D architecture. Combined geological and potential-field constrained inversion modelling of the Mount Painter Province was conducted to assess the validity of the geological models of the region. Magnetic susceptibility constrained stochastic property inversions indicates that the northeast to southwest structural trend of the relatively magnetic meta-sedimentary rocks of the Radium Creek Group in the Mount Painter Inlier is reconcilable with the similar, northeast to southwest trending positive magnetic anomalies in the region. Radium Creek Group packages are the major contributor of the total magnetic response of the region. However field mapping and the results of initial density constrained stochastic property inversion modelling do not correlate with a large residual negative gravity anomaly central to the region. Further density constrained inversion modelling indicates that an additional large body of relatively low density material is needed within the model space to account for this negative density anomaly. Through sensitivity analysis of multiple geometrical and varied potential-field property inversions, the best-fitting model records a reduction in gravity rms misfit from 21.9 to 1.69 mGal, representing a reduction from 56 to 4.5 per cent in respect to the total dynamic range of 37.5 mGal of the residual anomaly. This best-fitting model incorporates a volumetrically significant source

  5. Ivan Rančić: A forgotten painter of flowers and landscapes

    Marković Kamenko M.

    2014-01-01

    Full Text Available Ivan Rančić was born in the Kraljevo village, in eastern Serbia to a family of farmers on 19th, February, 1906. Very little data about him has been preserved, therefore, this paper is an attempt to make a reconstruction of his life and work. He attended primary school in his birth place, lower secondary school he finished in Knjazevac and Military Academy in Belgrade. After completing the National Academy in 1934, he was sent to Zagreb where he got his first post. He lived there with his wife and his son until the capitulation of the country in 1941. A few months after the collapse of the country, he was arrested and sent to Ljubljana and three months later to a concentration camp in Austria. He spent about fifteen months in that camp in during which time he intensively studied painting. He fled from the camp to Switzerland and stayed there until his death in 1987. According to some letters he sent to his wife in Nis, some of his paintings he created during his time in the camp, ne took to Switzerland where he eventually sold them. He did the toughest jobs there in order to survive and painted extensively. After World War II he graduated from the School of Fine Arts in Lausanne. Later on he had two exhibitions at the New Gallery of Modern Art. Ivan Rančić came a long way from an unknown beginner to a respected prominent artist. He left behind about 350 works, many of which he sold during his life, mainly landscapes and still life in oil, watercolor and pastel. He was neither concerned about styles and trends nor did he believe in the old and the new. If he came to a certain specific manner of painting, it is because at one point it was imposed on him as the only proper way of expression. The analysis of Rančić's paintings leads to the conclusion that his creation had gone through four phases. The first one (started in the concentration camp in Austria during which he painted still lifes without full sketches, previous studies, and the use

  6. Going “old school”: From bedside manner to deskside manner

    David Fleischman

    2015-08-01

    Full Text Available Interaction between tertiary educators and students, we contend, improves trust and betters student responses to emotional distress while at university. Therefore, we introduce the “Deskside Manner Framework” as an emerging practice in the tertiary teaching and learning context to aid student transition success. Based on concepts and practice that originated primarily in the medical profession and later in other high credence professional contexts, the deskside manner framework includes: show respect, critical listening, the four Bs and follow up. Deskside manner is transferrable and we aim to facilitate it through workshops and by developing a digital repository of educator-student interaction stories.  

  7. Institutional traditions in teachers' manners of teaching

    Lundqvist, Eva; Almqvist, Jonas; Östman, Leif

    2012-03-01

    The aim of this article is to make a close case study of one teacher's teaching in relation to established traditions within science education in Sweden. The teacher's manner of teaching is analysed with the help of an epistemological move analysis. The moves made by the teacher are then compared in a context of educational philosophy and selective tradition. In the analyses the focus is to study the process of teaching and learning in action in institutionalised and socially shared practices. The empirical material consists of video recordings of four lessons with the same group of students and the same teacher. The students are all in Year 7 in a Swedish 9-year compulsory school. During these lessons the students work with a subject area called "Properties of materials". The results show that the teacher makes a number of different moves with regard to how to proceed and come to a conclusion about what the substances are. Many of these moves are special in that they indicate that the students need to be able to handle the procedural level of school science. These moves do not deal directly with the knowledge production process, but with methodological aspects. The function of the moves turns the students' attention from one source of knowledge to another. The moves are aimed at helping the students to help themselves, since it is through their own activity and their own thinking that learning takes place. This is characteristic in the teacher's manner of teaching. When compared in a context of educational philosophy, this manner of teaching has similarities with progressentialism; a mixture of essentialism and progressivism. This educational philosophy is a central aspect of what is called the academic tradition—a selective tradition common in science education in Sweden between 1960 and 1990.

  8. Dermal, inhalation, and internal exposure to 1,6-HDI and its oligomers in car body repair shop workers and industrial spray painters.

    Pronk, A; Yu, F; Vlaanderen, J; Tielemans, E; Preller, L; Bobeldijk, I; Deddens, J A; Latza, U; Baur, X; Heederik, D

    2006-09-01

    To study inhalation and dermal exposure to hexamethylene diisocyanate (HDI) and its oligomers as well as personal protection equipment (PPE) use during task performance in conjunction with urinary hexamethylene diamine (HDA) in car body repair shop workers and industrial spray painters. Personal task based inhalation samples (n = 95) were collected from six car body repair shops and five industrial painting companies using impingers with di-n-butylamine (DBA) in toluene. In parallel, dermal exposure was assessed using nitril rubber gloves. Gloves were submerged into DBA in toluene after sampling. Analysis for HDI and its oligomers was performed by LC-MS/MS. Urine samples were collected from 55 workers (n = 291) and analysed for HDA by GC-MS. Inhalation exposure was strongly associated with tasks during which aerosolisation occurs. Dermal exposure occurred during tasks that involve direct handling of paint. In car body repair shops associations were found between detectable dermal exposure and glove use (odds ratio (OR) 0.22, 95% confidence interval (CI) 0.09 to 0.57) and inhalation exposure level (OR 1.34, 95% CI 0.97 to 1.84 for a 10-fold increase). HDA in urine could be demonstrated in 36% and 10% of car body repair shop workers and industrial painting company workers respectively. In car body repair shops, the frequency of detectable HDA was significantly elevated at the end of the working day (OR 2.13, 95% CI 1.07 to 4.22 for 3-6 pm v 0-8 am). In both branches HDA was detected in urine of approximately 25% of the spray painters. In addition HDA was detected in urine of a large proportion of non-spray painters in car body repair shops. Although (spray) painting with lacquers containing isocyanate hardeners results in the highest external exposures to HDI and oligomers, workers that do not perform paint related tasks may also receive a considerable internal dose.

  9. Partnership between painters and sculptors in 17th-century Spain: on model drawings by Francisco Rizi for an altarpiece of the Expectant Virgin

    Lamas-Delgado, Eduardo

    2013-01-01

    Full Text Available This paper deals with a case study of the collaboration between sculptors and painters in the context of the construction of altarpieces in 17th-century Spain. It analyses a drawing by Francisco Rizi (Madrid, 1614-Escorial, 1685 in the British Museum depicting a sculptural group and fragments of an architectural framework, and relates it to two other drawings by the same artist in the National Library of Spain. They are identified as fragments of the design drawing of the former altarpiece of the Expectant Virgin in the church of the Calced Trinitarians in Madrid.

  10. Selected topics in grand unification

    Seckel, D.

    1983-01-01

    This dissertation is a collection of four pieces of research dealing with grand unification. The topics are neutron oscillation, CP violation, magnetic monopole abundance and distribution in neutron stars, and a proposal for an inflationary cosmology driven by stress-energy in domain walls

  11. Introduction to grand unification theories

    Kang, Kyungsik

    1980-01-01

    We introduce the Georgi-Glashow model based on the minimal gauge group SU(5) as a prototype grand unification theory of the electroweak and strong interactions. Simple estimation of sin 2 thetasub(W) in the symmetry limit and the renormalization corrections at the energy scale of Msub(W) are given along wich other successes of the SU(5) model

  12. Coordinated Exploration for Grand Challenges

    Ørding Olsen, Anders; Sofka, Wolfgang; Grimpe, Christoph

    2016-01-01

    Grand challenges are among the most complex problems for modern societies. Many governments and foundations provide substantial resources to encourage the search for solutions. Due to the significance of these problems, organizations often form partnerships in what we call search consortia to eng...

  13. Results from KASCADE–Grande

    Bertaina, M.; Apel, W.D.; Arteaga-Velázquez, J.C.; Bekk, K.; Blümer, J.; Bozdog, H.; Brancus, I.M.; Buchholz, P.; Cantoni, E.; Chiavassa, A.; Cossavella, F.

    2012-01-01

    The KASCADE–Grande experiment, located at Karlsruhe Institute of Technology (Germany) is a multi-component extensive air-shower experiment devoted to the study of cosmic rays and their interactions at primary energies 10 14 –10 18 eV. Main goals of the experiment are the measurement of the all-particle energy spectrum and mass composition in the 10 16 –10 18 eV range by sampling charged (N ch ) and muon (N μ ) components of the air shower. The method to derive the energy spectrum and its uncertainties, as well as the implications of the obtained result, is discussed. An overview of the analyses performed by KASCADE–Grande to derive the mass composition of the measured high-energy comic rays is presented as well.

  14. Results from KASCADE-Grande

    Bertaina, M., E-mail: bertaina@to.infn.it [Dipartimento di Fisica Generale dell' Universita, Torino (Italy); Apel, W.D. [Institut fuer Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Arteaga-Velazquez, J.C. [Universidad Michoacana, Instituto de Fisica y Matematicas, Morelia (Mexico); Bekk, K. [Institut fuer Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Bluemer, J. [Institut fuer Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Institut fuer Experimentelle Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Bozdog, H. [Institut fuer Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); Brancus, I.M. [National Institute of Physics and Nuclear Engineering, Bucharest (Romania); Buchholz, P. [Fachbereich Physik, Universitaet Siegen (Germany); Cantoni, E. [Dipartimento di Fisica Generale dell' Universita, Torino (Italy); Istituto di Fisica dello Spazio Interplanetario, INAF Torino (Italy); Chiavassa, A. [Dipartimento di Fisica Generale dell' Universita, Torino (Italy); Cossavella, F. [Institut fuer Experimentelle Kernphysik, KIT - Karlsruher Institut fuer Technologie (Germany); and others

    2012-11-11

    The KASCADE-Grande experiment, located at Karlsruhe Institute of Technology (Germany) is a multi-component extensive air-shower experiment devoted to the study of cosmic rays and their interactions at primary energies 10{sup 14}-10{sup 18} eV. Main goals of the experiment are the measurement of the all-particle energy spectrum and mass composition in the 10{sup 16}-10{sup 18} eV range by sampling charged (N{sub ch}) and muon (N{sub {mu}}) components of the air shower. The method to derive the energy spectrum and its uncertainties, as well as the implications of the obtained result, is discussed. An overview of the analyses performed by KASCADE-Grande to derive the mass composition of the measured high-energy comic rays is presented as well.

  15. Cassini's Grand Finale Science Highlights

    Spilker, Linda

    2017-10-01

    After 13 years in orbit, the Cassini-Huygens Mission to Saturn ended in a science-rich blaze of glory. Cassini returned its final bits of unique science data on September 15, 2017, as it plunged into Saturn's atmosphere satisfying planetary protection requirements. Cassini's Grand Finale covered a period of roughly five months and ended with the first time exploration of the region between the rings and planet.The final close flyby of Titan in late April 2017 propelled Cassini across Saturn’s main rings and into its Grand Finale orbits; 22 orbits that repeatedly dove between Saturn’s innermost rings and upper atmosphere making Cassini the first spacecraft to explore this region. The last orbit turned the spacecraft into the first Saturn upper atmospheric probe.The Grand Finale orbits provided highest resolution observations of both the rings and Saturn, and in-situ sampling of the ring particle composition, Saturn's atmosphere, plasma, and innermost radiation belts. The gravitational field was measured to unprecedented accuracy, providing information on the interior structure of the planet, winds in the deeper atmosphere, and mass of the rings. The magnetic field provided insight into the physical nature of the magnetic dynamo and structure of the internal magnetic field. The ion and neutral mass spectrometer sampled the upper atmosphere for molecules that escape the atmosphere in addition to molecules originating from the rings. The cosmic dust analyzer directly sampled the composition from different parts of the main rings for the first time. Fields and particles instruments directly measured the plasma environment between the rings and planet.Science highlights and new mysteries gleaned to date from the Grand Finale orbits will be discussed.The research described in this paper was carried out in part at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration. Copyright 2017

  16. Grandes números primos

    Bang, Thöger

    2012-01-01

    En las escuelas danesas la teoría de los números se ha ido restringiendo gradualmente hasta no incluir sino la demostración de la descomposición univoca de los números enteros en números primos y la demostración del teorema clásico de EUCLIDES sobre la existencia de un número primo arbitrariamente grande.

  17. Grand unification theory and technicolor

    Rubakov, V.A.; Shaposhnikov, M.E.

    1983-01-01

    The lecture course can be considered as introduction to the problems concerning grand unification models. The course is incomplete. Such problems as CP-violations in strong interactions and the problem of gravitational interaction inclusion in the scheme of grand unification theory are not touched upon. Models of early unification, in which strong, weak and electromagnetic interactions are compared according to the ''strength'' at energies of about 10 5 -10 6 GeV, are not discussed. Models with horizontal symmetry, considering different generations of quarks and leptons from one viewpoint, are not analyzed. Cosmological applications of supersymmetric unified theories are not considered. Certain problems of standard elementary particle theory, philosophy of the great unification, general properties of the grand unification models and the main principles of the construction of models: the SU(5) model, models on the SO(10) groups, have been considered. The problem of supersymmetric unification hierarchies, supersymmetric generalization of the minimum SU(5) model, supersymmetry violation and the problem of hierarchies, phenomenology of the o.rand unification models, cosmological application and technicolour, are discussed

  18. Dermal, inhalation, and internal exposure to 1,6‐HDI and its oligomers in car body repair shop workers and industrial spray painters

    Pronk, A; Yu, F; Vlaanderen, J; Tielemans, E; Preller, L; Bobeldijk, I; Deddens, J A; Latza, U; Baur, X; Heederik, D

    2006-01-01

    Objectives To study inhalation and dermal exposure to hexamethylene diisocyanate (HDI) and its oligomers as well as personal protection equipment (PPE) use during task performance in conjunction with urinary hexamethylene diamine (HDA) in car body repair shop workers and industrial spray painters. Methods Personal task based inhalation samples (n = 95) were collected from six car body repair shops and five industrial painting companies using impingers with di‐n‐butylamine (DBA) in toluene. In parallel, dermal exposure was assessed using nitril rubber gloves. Gloves were submerged into DBA in toluene after sampling. Analysis for HDI and its oligomers was performed by LC‐MS/MS. Urine samples were collected from 55 workers (n = 291) and analysed for HDA by GC‐MS. Results Inhalation exposure was strongly associated with tasks during which aerosolisation occurs. Dermal exposure occurred during tasks that involve direct handling of paint. In car body repair shops associations were found between detectable dermal exposure and glove use (odds ratio (OR) 0.22, 95% confidence interval (CI) 0.09 to 0.57) and inhalation exposure level (OR 1.34, 95% CI 0.97 to 1.84 for a 10‐fold increase). HDA in urine could be demonstrated in 36% and 10% of car body repair shop workers and industrial painting company workers respectively. In car body repair shops, the frequency of detectable HDA was significantly elevated at the end of the working day (OR 2.13, 95% CI 1.07 to 4.22 for 3–6 pm v 0–8 am). In both branches HDA was detected in urine of ∼25% of the spray painters. In addition HDA was detected in urine of a large proportion of non‐spray painters in car body repair shops. Conclusion Although (spray) painting with lacquers containing isocyanate hardeners results in the highest external exposures to HDI and oligomers, workers that do not perform paint related tasks may also receive a considerable internal dose. PMID:16728504

  19. Lung cancer risk in painters: a meta-analysis Risco de câncer de pulmão em pintores: uma meta-análise

    Neela Guha

    2011-08-01

    Full Text Available We conducted a meta-analysis to quantitatively compare the association between occupation as a painter and the incidence or mortality from lung cancer. PubMed and the reference lists of pertinent publications were searched and reviewed. For the meta-analysis, we used data from 47 independent cohort, record linkage, and case-control studies (from a total of 74 reports, including > 11,000 incident cases or deaths from lung cancer among painters. Three authors independently abstracted data and assessed study quality. The summary relative risk (meta-RR, random effects for lung cancer in paint-ers was 1.35 [95% confidence interval (CI, 1.29-1.41; 47 studies] and 1.35 (95% CI, 1.21-1.51; 27 studies after controlling for smoking. The relative risk was higher in never-smokers (meta-RR = 2.00; 95% CI, 1.09-3.67; 3studies and persisted when restricted to studies that adjusted for other occupational exposures (meta-RR = 1.57; 95% CI, 1.21-2.04; 5 studies. These results support the conclusion that occupational exposures in painters are causally associated with the risk of lung cancer.Conduziu-se uma meta-análise para comparar quatitativamente a associação entre o trabalho de pintor e a incidência ou mortalidade por câncer de pulmão. PubMed e listas de referência de publicações pertinentes foram pesquisadas e revisadas. Para a análise, foram usados dados de 47 estudos de caso, coorte independente e ligação de dados (de um total de 74 relatórios, incluindo > 11 mil casos de incidentes ou morte por câncer de pulmão entre pintores. Três autores coletaram dados e avaliaram a qualidade de estudo. O risco relativo (meta-RR, efeitos aleatórios de câncer de pulmão em pintores foi de 1,35 [95% intervalo de confiança (IC, 1,29-1,41; 47 estudos] e 1,35 (95% IC, 1,21-1,51; 27 estudos depois de se destacar os fumantes. O risco relativo foi maior naqueles que nunca fumaram (meta-RR = 2.00; 95% CI, 1,09-3,67; 3 estudos e persistiu quanto restringido a

  20. Grand unification: quo vadis domine

    Senjanovic, G.

    1985-01-01

    The present theoretical and experimental situation with grand unification is summarized. The issues of proton decay and the Weinberg angle are addressed, going through the predictions of both the standard SU(5) theory and its supersymmetric extension. The SO(10) theory, which provides a minimal one family model, is then studied. The gravitational characteristics of domain walls and strings are then discussed. It is argued that there is a need to go beyond SO(10) in order to incorporate a unified picture of families. This leads to the prediction of mirror fermions, whose physics is analyzed. 31 refs

  1. Graafikatriennaali grand prix Korea kunstnikule

    1998-01-01

    Tallinna XI graafikatriennaali rahvusvaheline žürii andis grand prix korea kunstnikule Chung¡Sang-Gonile, kolm võrdset preemiat - soome kunstnikele Anita Jensenile ja Tapani Mikkonenile ning jaapani kunstnikule Estuko Obatale. Eesti Kunstimuuseumi preemia - Wendy Swallow. Tallinna linna preemia ja Ivar Luki sponsoripreemia - Walter Jule. Sponsoripreemiad : Paletti Eesti AS preemia - Inga Heamägi; Rannila Profiili preemia - Mojca Zlokarnik; UNDP preemia - Andrea Juan. Rotermanni soolalao arhitektuuri- ja kunstikeskuse diplom - Lis Ingram, Heli Päivikki Kurunsaari, Randi Strand, Wendy Swallow

  2. Grand Challenges of Enterprise Integration

    Brosey, W.D; Neal, R.E.; Marks, D.

    2001-04-01

    Enterprise Integration connects and combines people, processes, systems, and technologies to ensure that the right people and the right processes have the right information and the right resources at the right time. A consensus roadmap for Technologies for Enterprise Integration was created as part of an industry/government/academia partnership in the Integrated Manufacturing Technology Initiative (IMTI). Two of the grand challenges identified by the roadmapping effort will be addressed here--Customer Responsive Enterprises and Totally Connected Enterprises. Each of these challenges is briefly discussed as to the current state of industry and the future vision as developed in the roadmap.

  3. Grand Challenges for Environmental Magnetism

    Verosub, K. L.

    2009-05-01

    The development of new, inexpensive, and rapid geochemical methods for determining the ages of geologic materials, their elemental composition, and their isotopic ratios over a broad array of elements puts into sharp focus the question: What information can environmental magnetic methods provide that can't be obtained using these other methods? Because iron is ubiquitous in the Earth's crust and because it exists in so many different forms, a discipline that looks in detail at iron-bearing minerals does have the potential to make significant contributions to the study of surficial processes. However, to reach that potential requires the development of new environmental magnetic methods. I would like to put forward three Grand Challenges for environmental magnetism that have the potential to move the field forward to a new level of scientific sophistication and that will allow environmental magnetists to compete successfully in a world increasingly dominated by geochemists. The first Grand Challenge is the development of new techniques that lead to the direct and unambiguous identification of the full suite of magnetic minerals. For many environmental magnetic applications, the key magnetic minerals are not just magnetite and hematite but also iron oxy-hydroxides (goethite, lepidocrocite, akaganeite, ferrihydrite), carbonates (siderite) and sulfides (pyrrhotite and greigite) as well as compounds involving iron and other transition metals (cobalt and nickel). The second Grand Challenge is the development of new analytical methods that provide specific quantitative values for the amount of each magnetic mineral present in a sample. One promising approach to this problem is the application of two- or three-component multivariate analysis to arrays of downcore environmental magnetic parameters. The third Grand Challenge is the development of new ways of determining, not just the average values, but the actual distributions of grain sizes and coercivities of each mineral

  4. The Grand Challenges of Nanotechnology

    Lane, Neal

    2001-01-01

    Amazing breakthroughs and advances continue to be made in nanoscale science and engineering and the rapidly emerging field of nanotechnology, including near-commercial applications in biomedicine, computing and environmental protection. The National Nanotechnology Initiative, begun by the Clinton Administration has placed nanoscale research on a new funding trajectory. But, many 'grand challenges' must be overcome, technical ones as well as those related to funding, science and technology workforce, and the need for stronger collaboration across discipline, organizations, government agencies and with other countries

  5. Do children with obesity have worse table manners? Associations between child table manners, weight status and weight gain.

    Briones, Naomi F; Cesaro, Robert J; Appugliese, Danielle P; Miller, Alison L; Rosenblum, Katherine L; Pesch, Megan H

    2018-06-01

    Children with obesity experience stigma stemming from stereotypes, one such stereotype is that people with obesity are "sloppy" or have poor manners. Teaching children "proper table manners" has been proposed as an obesity prevention strategy. Little is known about the association between children's weight status and table manners. To examine correlates of child table manners and to examine the association of child table manners with child obese weight status and prospective change in child body mass index z-score (BMIz). Mother-child dyads (N = 228) participated in a videotaped laboratory eating task with cupcakes. Coding schemes to capture child table manners (making crumbs, chewing with mouth open, getting food on face, shoving food in mouth, slouching, and getting out of seat), and maternal attentiveness to child table manners, were reliably applied. Anthropometrics were measured at baseline and at follow-up two years later. Regression analyses examined the association of participant characteristics with child table manners, as well as the associations of child table manners with child obese weight status, and prospective change in BMIz/year. Predictors of poorer child table manners were younger child age, greater cupcake consumption, and greater maternal attentiveness to child table manners. Poorer child table manners were not associated with child obese (vs. not) weight status, but were associated with a prospective decrease in BMIz/year in children with overweight/obesity. Obesity interventions to improve table manners may be perpetuating unfavorable stereotypes and stigma. Future work investigating these associations is warranted to inform childhood obesity guidelines around table manners. Copyright © 2018 Elsevier Ltd. All rights reserved.

  6. 26 CFR 1.9005-4 - Manner of exercising election.

    2010-04-01

    ... 26 Internal Revenue 13 2010-04-01 2010-04-01 false Manner of exercising election. 1.9005-4 Section 1.9005-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES General Actuarial Valuations § 1.9005-4 Manner of exercising election. (a...

  7. 26 CFR 1.9004-4 - Manner of exercising election.

    2010-04-01

    ... 26 Internal Revenue 13 2010-04-01 2010-04-01 false Manner of exercising election. 1.9004-4 Section 1.9004-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES General Actuarial Valuations § 1.9004-4 Manner of exercising election. (a...

  8. 26 CFR 1.9002-8 - Manner of exercising elections.

    2010-04-01

    ... 26 Internal Revenue 13 2010-04-01 2010-04-01 false Manner of exercising elections. 1.9002-8 Section 1.9002-8 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES General Actuarial Valuations § 1.9002-8 Manner of exercising elections...

  9. 26 CFR 1.9003-4 - Manner of exercising election.

    2010-04-01

    ... 26 Internal Revenue 13 2010-04-01 2010-04-01 false Manner of exercising election. 1.9003-4 Section 1.9003-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES General Actuarial Valuations § 1.9003-4 Manner of exercising election. (a...

  10. 26 CFR 1.853-4 - Manner of making election.

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Manner of making election. 1.853-4 Section 1.853-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Regulated Investment Companies and Real Estate Investment Trusts § 1.853-4 Manner of...

  11. Mannerisms of the Elderly and Approaches to Rapport.

    French, Warren A.; And Others

    1980-01-01

    Many older adults react to old age with empirically identified distinguishable mannerisms. Using these mannerisms, or behavior patterns, as a basis for rapport, gerontologists can: (1) uncover causes of adjustment problems; (2) assess seriousness of problems; and (3) implement counseling suggestions. (Author/JAC)

  12. 29 CFR 1905.21 - Manner of service.

    2010-07-01

    ...-STEIGER OCCUPATIONAL SAFETY AND HEALTH ACT OF 1970 Hearings § 1905.21 Manner of service. Service of any... 29 Labor 5 2010-07-01 2010-07-01 false Manner of service. 1905.21 Section 1905.21 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR...

  13. Google Earth Grand Tour Themes

    De Paor, D. G.; Whitmeyer, S. J.; Bentley, C.; Dordevic, M. M.

    2014-12-01

    As part of an NSF TUES Type 3 project entitled "Google Earth for Onsite and Distance Education (GEODE)," we are assembling a "Grand Tour" of locations on Earth and other terrestrial bodies that every geoscience student should know about and visit at least in virtual reality. Based on feedback from colleagues at previous meetings, we have identified nine Grand Tour themes: "Plates and Plumes," "Rocks and Regions," "Geology Through Time," "The Mapping Challenge*," "U.S. National Parks*," "The Magical Mystery Tour*," "Resources and Hazards," "Planets and Moons," and "Top of the Pops." Themes marked with an asterisk are most developed at this stage and will be demonstrated in real time. The Mapping Challenge invites students to trace geological contacts, measure bedding strike and dip and the plunge, trend, and facing of a fold. There is an advanced tool for modeling periclinal folds. The challenge is presented in a game-like format with an emphasis on puzzle-solving that will appeal to students regardless of gender. For the tour of U.S. national parks, we divided the most geologically important parks into four groups—Western Pacific, West Coast, Rockies, and East Coast. We are combining our own team's GigaPan imagery with imagery already available on the Internet. There is a great deal of imagery just waiting to be annotated for geological education purposes. The Magical Mystery Tour takes students to Google Streetview locations selected by instructors. Students are presented with questions or tasks and are given automatic feedback. Other themes are under development. Within each theme, we are crowd-sourcing contributions from colleagues and inviting colleagues to vote for or against proposed locations and student interactions. The GEODE team includes the authors and: Heather Almquist, Stephen Burgin, Cinzia Cervato, Gene Cooper, Paul Karabinos, Terry Pavlis, Jen Piatek, Bill Richards, Jeff Ryan, Ron Schott, Kristen St. John, and Barb Tewksbury.

  14. Next Generation Innovation Policy and Grand Challenges

    Kuhlmann, Stefan; Rip, Arie

    2018-01-01

    The paper explores transformative ways to address Grand Challenges, while locating them in a broader diagnosis of ongoing changes. Coping with Grand Challenges is a challenge in its own right, for policy as well as for science, technology, and innovation actors. The paper presents building blocks

  15. Proton hexality in local grand unification

    Foerste, Stefan; Nilles, Hans Peter [Bonn Univ. (Germany). Bethe Center for Theoretical Physics and Physikalisches Institut; Ramos-Sanchez, Saul [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Vaudrevange, Patrick K.S. [Muenchen Univ. (Germany). Arnold Sommerfeld Center for Theoretical Physics

    2010-07-15

    Proton hexality is a discrete symmetry that avoids the problem of too fast proton decay in the supersymmetric extension of the standard model. Unfortunately it is inconsistent with conventional grand unification. We show that proton hexality can be incorporated in the scheme of ''Local Grand Unification'' discussed in the framework of model building in (heterotic) string theory. (orig.)

  16. La Grande: volver a empezar

    Julio Premat

    2011-07-01

    Full Text Available Este texto, borrador de un trabajo más amplio, pretende despejar algunas pistas de lectura de La grande, en tanto que paradójico final de la producción de Saer. Digo “paradójico” porque puede tomársela como una novela de comienzo o de origen : de un volver a empezar, en todos los sentidos del término. En esa perspectiva podrían estudiarse algunos núcleos temáticos (como el retorno o el recuerdo de cara a la construcción del texto, a la relación planteada con la tradición y a la singular historia de su escritura (y al material genético que rodea y completa esta novela a la vez inacabada y póstuma. En esta intervención, la idea es la de comentar tres textos, escenas o frases del texto, y a partir de allí esbozar pistas para un estudio que está en ciernes.Première ébauche d’un travail de plus d’ampleur, ce texte vise à éclairer quelques pistes de lecture de La grande, en tant que fin paradoxale de la production de Saer. Je dis « paradoxale » parce que l’on peut considérer cette œuvre comme un roman des commencements ou des origines : comme un retour aux débuts, dans tous les sens du terme. Dans cette perspective, plusieurs nœuds thématiques (comme le retour ou le souvenir pourraient être étudiés en relation à la construction du texte, à la relation qui s’établit avec la tradition et à la singulière histoire de son écriture (et au matériau génétique qui entoure et complète ce roman, à la fois inachevé et posthume. Il sera question ici de commenter trois textes, scènes ou phrases du texte, et d’ébaucher à partir de là quelques pistes pour une étude à l’état naissant.The objective of this text, a draft for a broader work, is to outline some reading clues for La grande, inasmuch as it constitutes a paradoxical ending of Saer’s production. I say “paradoxical” because we can consider this work a novel of beginnings or of origins: a return to the beginning, in every meaning of the

  17. Art, class and gender in Joseon dynasty Korea: representations of lower-class women by the scholar-painter Yun Duseo.

    Chung, Saehyang P

    2011-01-01

    This paper examines several pioneering genre paintings by the important scholar painter Yun Duseo (1668-1715), with its focus on their artistic sources which have not yet been explored so far. Painted on ramie, 'Women Picking Potherbs' is one of the most intriguing examples among Yun Duseo's oeuvre, which encompasses a broad variety of themes, including genre imagery, landscapes, portraits, dragons, and horses. Even among Yun Duseo's genre paintings, 'Women Picking Potherbs' is extraordinary, as recent scholarship regards it as the earliest independent representation of lower-class women in the history of Korean art. In particular, Yun Duseo painted two women who were working ourdoors to gather spring potherbs. In a conservative Confucian society, it was extraordinary women who were working outdoors. Hence, Yun Duseo occupies a highly important place in Korean painting. Furthermore, even though Yun Duseo came from the upper-class, he often painted images of lower class people working. It is possible that Yun Duseo was familiar with the book titled "Tian gong kai wu" (Exploitation of the Works of Nature) which was published in the 17th century. By identifying the probable body of his artistic sources in the book known as "Tian gong kai wu," it will be possible to assess the innovations and limitations found in 'Women Picking Potherbs'.

  18. Improving the livelihoods of wool producers in a sustainable manner ...

    Improving the livelihoods of wool producers in a sustainable manner by optimizing the woolled sheep production systems within the communal farming area of the Eastern Cape. “A vision that is future directed”

  19. The Manners of Liberalism: A Question of Limits.

    Allen, William B.

    1982-01-01

    The argument that liberal education leads people to substitute intellectual tolerance or ambiguity for righteous indignation is criticized, with reference to Harriet Beecher Stowe's portrayal of Thomas Jefferson, his liberalism, and democratic manners. (MSE)

  20. Giovanni Cingolani pittore e restauratore fra l'Italia, il Vaticano e l'Argentina tra Ottocento e Novecento / Giovanni Cingolani painter and restorer between Italy, Vatican and Argentina in the 19th and 20th Centuries

    Francesca Coltrinari

    2015-02-01

    The life of Giovanni Cingolani (Montecassiano, 1859 – Santa Fe, 1932 takes place between Italy and Argentina at the turn of the 19th and 20th centuries. Cingolani redeems his humble origins with a successful career as a painter and restorer in Rome between 1880 and 1908. Thanks to the relations with prelates and painters of Perugia, close to Pope Leo XIII, the artist fits himself in the papal circles, devoting himself to painting religious and to the portrait. Came into contact with Ludovico Seitz, director of the Vatican Museums, participates in the major restorations in the Borgia apartment, in the chapel Niccolina, in the Vatican Stanze and in the Sistine Chapel. In 1909 he emigrated to Santa Fe, where he worked as a church decorator and portrait painter, devoting himself intensely to teaching: thanks to unpublished documents, especially the correspondence between Cingolani, his daughter Leonilde and the director of the library of Macerata, Giovanni Spadoni, you can learn many details about his life and the Italian and Argentines artistic milieus he frequented. The paper wants to disclose this almost unknown artist, “migrant” between Italy and Argentina, highlighting his role of disseminator of European academic tradition in Latin America.

  1. A Grande Reportagem no contexto informativo SIC

    Colaço, Vanessa Alexandra Francisco

    2014-01-01

    Os telespectadores querem ver grandes reportagens? Como evoluíram as audiências da Grande Reportagem SIC? É este o produto premium da estação? Terá este formato um investimento e continuidade garantidas? Estas são algumas das questões formuladas e às quais se procurou dar resposta neste Relatório de Estágio. Neste trabalho traça-se o perfil do programa Grande Reportagem SIC, clarificando a linha editorial que lhe serviu de base, procurando perceber as suas dinâmicas e passando em revista mome...

  2. Supersymmetry and supergravity: Phenomenology and grand unification

    Arnowitt, R.; Nath, P.

    1993-01-01

    A survey is given of supersymmetry and supergravity and their phenomenology. Some of the topics discussed are the basic ideas of global supersymmetry, the minimal supersymmetric Standard Model (MSSM) and its phenomenology, the basic ideas of local supersymmetry (supergravity), grand unification, supersymmetry breaking in supergravity grand unified models, radiative breaking of SU(2) x U(1), proton decay, cosmological constraints, and predictions of supergravity grand unified models. While the number of detailed derivations are necessarily limited, a sufficient number of results are given so that a reader can get a working knowledge of this field

  3. 29 CFR 1614.703 - Manner and format of data.

    2010-07-01

    ... § 1614.704(a) through (m). (3) When posting data pursuant to § 1614.704(d) and (j), bases of... 29 Labor 4 2010-07-01 2010-07-01 false Manner and format of data. 1614.703 Section 1614.703 Labor... Retaliation Act of 2002 (No FEAR Act) § 1614.703 Manner and format of data. (a) Agencies shall post their...

  4. Las cinco grandes dimensiones de la personalidad

    Jan ter Laak

    1996-12-01

    Full Text Available Este artículo revisa las distintas posiciones teóricas sobre las cinco grandes dimensiones de la personalidad, mostrando las semejanzas y diferencias entre las posturas teóricas. Esta contribución presenta lo siguiente: (a la génesis del contenido y la estructura de las cinco dimensiones; (b la fortaleza de las cinco dimensiones; (e la relación de las cinco grandes dimensiones con otros constructos de personalidad; (d discute el valor predictivo de las puntuaciones del perfil de las cinco dimensiones para criterios pertinentes; (e analiza el estatus teórico de las cinco dimensiones; (f discute críticas históricas sobre las cinco grandes dimensiones y se formulan respuestas a estas críticas; (g hace conjeturas para el futuro de las cinco grandes dimensiones; y (h concluye con algunas conclusiones y comentarios.

  5. Grand unification and gravity - selected topics

    Zee, A.

    1981-09-01

    The material given here was presented in lectures delivered at the 4th Kyoto Summer Institute on Grand Unification and Related Topics. It consists of six sections. The sections are: the family problem, fermion mass hierarchy, maximal local symmetry, operator analysis of new physics, dynamically generated gravity, and Kaluza theory and grand unification. The last section contains a (hopefully) pedagogical introduction to Kaluza theory. For pedagogical completeness, several appendices reviewing some elementary notions of differential geometry have been added

  6. 21 CFR 1306.05 - Manner of issuance of prescriptions.

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Manner of issuance of prescriptions. 1306.05 Section 1306.05 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE PRESCRIPTIONS... revised, effective June 1, 2010. For the convenience of the user, therevised text is set forth as follows...

  7. Stereotypes: A Preliminary Report on Mannerisms and Blindisms.

    Leonhardt, M.

    1990-01-01

    The article describes current research on stereotypes in a group of blind children in Barcelona, Spain. Mannerisms and blindisms covering a range of verbal and motor behavior are defined and discussed, as are the variables of behavior related to them. (Author/DB)

  8. 26 CFR 1.1071-4 - Manner of election.

    2010-04-01

    ... corporation, the statement shall be signed with the corporate name, followed by the signature and title of an officer of the corporation empowered to sign for the corporation, and the corporate seal must be affixed...) INCOME TAXES Changes to Effectuate F.c.c. Policy § 1.1071-4 Manner of election. (a) An election under the...

  9. 20 CFR 335.2 - Manner of claiming sickness benefits.

    2010-04-01

    ..., or in the case of a female employee, pregnancy, miscarriage, or childbirth, an employee must file the... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Manner of claiming sickness benefits. 335.2 Section 335.2 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER THE RAILROAD UNEMPLOYMENT...

  10. 18 CFR 344.2 - Manner of submitting quotations.

    2010-04-01

    ... quotations. 344.2 Section 344.2 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE INTERSTATE COMMERCE ACT FILING QUOTATIONS FOR U.S. GOVERNMENT SHIPMENTS AT REDUCED RATES § 344.2 Manner of submitting quotations. (a) The quotation or tender...

  11. 2010 Panel on the Biomaterials Grand Challenges

    Reichert, William “Monty”; Ratner, Buddy D.; Anderson, James; Coury, Art; Hoffman, Allan S.; Laurencin, Cato T.; Tirrell, David

    2014-01-01

    In 2009, the National Academy for Engineering issued the Grand Challenges for Engineering in the 21st Century comprised of 14 technical challenges that must be addressed to build a healthy, profitable, sustainable, and secure global community (http://www.engineeringchallenges.org). Although crucial, none of the NEA Grand Challenges adequately addressed the challenges that face the biomaterials community. In response to the NAE Grand Challenges, Monty Reichert of Duke University organized a panel entitled Grand Challenges in Biomaterials at the at the 2010 Society for Biomaterials Annual Meeting in Seattle. Six members of the National Academies—Buddy Ratner, James Anderson, Allan Hoffman, Art Coury, Cato Laurencin, and David Tirrell—were asked to propose a grand challenge to the audience that, if met, would significantly impact the future of biomaterials and medical devices. Successfully meeting these challenges will speed the 60-plus year transition from commodity, off-the-shelf biomaterials to bioengineered chemistries, and biomaterial devices that will significantly advance our ability to address patient needs and also to create new market opportunities. PMID:21171147

  12. Solar Cycle Variability and Grand Minima Induced by Joy's Law Scatter

    Karak, Bidya Binay; Miesch, Mark S.

    2017-08-01

    The strength of the solar cycle varies from one cycle to another in an irregular manner and the extreme example of this irregularity is the Maunder minimum when Sun produced only a few spots for several years. We explore the cause of these variabilities using a 3D Babcock--Leighton dynamo. In this model, based on the toroidal flux at the base of the convection zone, bipolar magnetic regions (BMRs) are produced with flux, tilt angle, and time of emergence all obtain from their observed distributions. The dynamo growth is limited by a tilt quenching.The randomnesses in the BMR emergences make the poloidal field unequal and eventually cause an unequal solar cycle. When observed fluctuations of BMR tilts around Joy's law, i.e., a standard deviation of 15 degrees, are considered, our model produces a variation in the solar cycle comparable to the observed solar cycle variability. Tilt scatter also causes occasional Maunder-like grand minima, although the observed scatter does not reproduce correct statistics of grand minima. However, when we double the tilt scatter, we find grand minima consistent with observations. Importantly, our dynamo model can operate even during grand minima with only a few BMRs, without requiring any additional alpha effect.

  13. NARRATIVE PERSPECTIVE MEDIATED BY MANNER OF MOTION VERBS

    Olesea BODEAN-VOZIAN

    2016-12-01

    Full Text Available There is typological variation in the way languages encode manner as an element of a motion event. Languages like English view it as relevant, and the lexicalization of the variety of ways to move results in a rich class of motion verbs, contrary to other types of languages, like Romanian, which leave the manner element to be encoded by verbids or adverbs (for these reasons some linguists refer to the first type as manner-rich and second type as manner-poor languages. Still, several studies contrasting typologically different languages showed that languages of the latter type are not so poor in manner-of-motion verbs. The question then might rather be: which manner components are more likely to be lexicalized?For research purposes, we distinguish manner in terms of objective elements (medium, speed or intensity and subjective elements (attitude, intention. The aim of the study is to focus on the manner-of-motion verbs that embed an evaluative or qualitative dimension of motion and to examine the way these verbs encode somebody’s perspective in a narrative. The first question in such a case is whose evaluation or point of view is being represented. The second one is how the subjective point of view (narrative perspective mediated through manner-of-motion verbs in an English narrative (The Lord of the Rings, by J.R.R. Tolkien is translated into Romanian, supposedly a manner-poor or low-manner language.PERSPECTIVA NARATIVĂ MEDIATĂ DE VERBELE DE MIŞCARE DE MODExistă o variaţie tipologică în felul în care limbile codifică modul ca element al unui eveniment de mişcare. Limbile precum engleza îl percep drept unul relevant, iar lexicalizarea gamei de mijloace de redare a mişcării a dat naştere unei clase bogate de verbe de mişcare, contrar altor tipuri de limbi, aşa ca româna, în care elementul ce redă modul este codificat de gerunziu sau adverbe. Din aceasta cauză, unii lingvişti numesc primul tip limbi bogate în verbe de mod (

  14. Effective Higgs theories in supersymmetric grand unification

    Zheng, Sibo [Chongqing University, Department of Physics, Chongqing (China)

    2017-09-15

    The effective Higgs theories at the TeV scale in supersymmetric SU(5) grand unification models are systematically derived. Restricted to extensions on 5{sub H} containing the Higgs sector we show that only two types of real (vector-like) models and one type of chiral model are found to be consistent with perturbative grand unification. While the chiral model has been excluded by the LHC data, the fate of perturbative unification will be uniquely determined by the two classes of vector-like models. (orig.)

  15. Grand Tour: immaginario, territorio e culture digitali

    Emiliano Ilardi

    2016-12-01

    Full Text Available Il Grand Tour può essere recuperato come asset narrativo utile per un intervento strategico di re-branding del viaggio in Italia? Il contributo analizza il contesto e le condizioni per una progettazione di questo livello nell’ambiente culturale dell’epoca digitale. Considerando gli archetipi moderni della mediazione dei luoghi come una grande riserva di senso, da riattivare sia nelle pratiche basate sui format seriali e transmediali che valorizzano i territori nella produzione creativa, sia nella costruzione di infrastrutture digitali e  transluoghi per la valorizzazione degli attrattori culturali.

  16. A Unified Grand Tour of Theoretical Physics

    Lawrie, Ian D

    2002-01-01

    A unified account of the principles of theoretical physics, A Unified Grand Tour of Theoretical Physics, Second Edition stresses the inter-relationships between areas that are usually treated as independent. The profound unifying influence of geometrical ideas, the powerful formal similarities between statistical mechanics and quantum field theory, and the ubiquitous role of symmetries in determining the essential structure of physical theories are emphasized throughout.This second edition conducts a grand tour of the fundamental theories that shape our modern understanding of the physical wor

  17. Along the Grand Trunk Road: The Photography of Raghubir Singh

    Chaya Chandrasekhar

    2013-05-01

    Full Text Available For more than two millennia, the historic Grand Trunk Road, the busy thoroughfare that extends some 1500 miles through north India and Pakistan served as the main artery of South Asia. It was also the gateway through which waves of immigrants, travelers, and invaders entered the subcontinent. As a result, a great deal of diversity and tolerance marks the road. Between 1988 and 1991, Raghubir Singh (1942-1999, one of India’s renowned documentary photographers, traveled and photographed the Indian stretch of the Road. Ninety-six photographs from his journeys appear in the publication, 'The Grand Trunk Road: A Passage Through India '(1995. Singh used the pictorial style of street photography that he is known for to capture everyday life along the path. Further, he emphasized the tremendous diversity he witnessed along the road through the selections he made for inclusion in the book and the specific manner in which he arranged many of them. By underscoring the heterogeneity, Singh provided a critical visual commentary of the political climate in India during the 1980s and early nineties. This period coincided with the rise of Hindu nationalism, which aimed to erase the subcontinent’s diverse past and promote instead the idea of a homogenous/Hindu India. By documenting the road in his uniquely pictorial style and arranging the photographs in his book to draw attention to the differences and tolerance witnessed along the path, Singh demonstrated that India was not a monolithic culture as the politics of the time claimed, but a rich interwoven fabric of many varied strands.

  18. Practicing leadership-as-practice in content and manner

    Raelin, Joe; Kempster, Stephen John; Youngs, Howard; Caroll, Brigid; Jackson, Brad

    2018-01-01

    A collective and collaborative response to an article appearing in Leadership’s “Leading Questions” department is prepared by a team subscribing to the leadership-as-practice approach. The focus is to represent the manner in which leadership-as-practice operates as a leadership theory and in its communal practice orientation. Among the themes addressed are leadership-as-practice’s theory development, its contribution in comparison to critical leadership theory, its approach to power, and its ...

  19. MANNER OF STOCKS SORTING USING CLUSTER ANALYSIS METHODS

    Jana Halčinová

    2014-06-01

    Full Text Available The aim of the present article is to show the possibility of using the methods of cluster analysis in classification of stocks of finished products. Cluster analysis creates groups (clusters of finished products according to similarity in demand i.e. customer requirements for each product. Manner stocks sorting of finished products by clusters is described a practical example. The resultants clusters are incorporated into the draft layout of the distribution warehouse.

  20. Hilbert's Grand Hotel with a series twist

    Wijeratne, Chanakya; Mamolo, Ami; Zazkis, Rina

    2014-08-01

    This paper presents a new twist on a familiar paradox, linking seemingly disparate ideas under one roof. Hilbert's Grand Hotel, a paradox which addresses infinite set comparisons is adapted and extended to incorporate ideas from calculus - namely infinite series. We present and resolve several variations, and invite the reader to explore his or her own variations.

  1. "Teine" võitis Prantsusmaal Grand Prix'

    2006-01-01

    Prantsusmaal Essonne'is toimuval 8. Euroopa filmifestivalil Cinessonne sai üliõpilaste žürii grand prix rahvusvahelises ühistöös valminud tantsufilm "Teine" ("Another") : režissöör Rene Vilbre. Ka teistest festivalidest, kus film osalenud

  2. The Virtual Grand Tour as Educational Paradigm

    Hansen, Per Skafte; Mouritsen, Lars

    2001-01-01

    The Virtual Grand Tour as defined here bears some resemblance to its 18th century ancestor: a wide range of individual topics are treated as a whole; a tutor, whether real or simulated, present or remote, is provided; a set of problem solving tools forms an integrated part of the "traveller...

  3. Grand Prix Eurovision: Eine Fankultur im Medienzeitalter

    Heinz Moser

    2017-06-01

    Full Text Available Der Grand Prix Eurovision ist seit Jahrzehnten eine der bekanntesten Unterhaltungssendungen im europäischen Raum. Dennoch erregte es Verwunderung, wenn der Schreibende Bekannten darüber berichtete, daß dies ein Forschungsgegenstand sei. Wurde von Interviews mit Grand Prix-Fans erzählt, so fielen schnell Aussagen wie: „Wie kann man sich nur für so etwas Abseitiges und Triviales wie den Grand Prix interessieren“. Dennoch bin ich der Meinung, daß Fankulturen für die entstehende Mediengesellschaft ein nicht unwichtiges Forschungsthema darstellen. Zwar geht es nicht um eine medienpädagogische Fragestellung im engeren Sinne; die Fans des Grand Prix Eurovision sind dem Jugendalter längst entwachsen. Dennoch handelt es sich bei Fangemeinschaften um Phänomene, die im Rahmen von Jugend- und Kinderkulturen von besonderer Relevanz sind. So meint Winter (1997, daß jugendliche Fanwelten eine bedeutende Rolle als Kristallisationspunkte kultureller Differenzierung spielen: ,Die Zugehörigkeit zu einer Fan weit ist Teil der jugendlichen Lebensbewältigung in der Postmoderne, denn in der Gemeinschaft der Fans können Jugendliche emotionale Allianzen eingehen, außeralltäglichen Beschäftigungen nachgehen, expressive Identitätsmuster gemeinschaftlich realisieren und sich mit ihrer Lebenssituation als Heranwachsende auseinandersetzen“ (Winter 1997, S. 51f..

  4. Grand Canyon Monitoring and Research Center

    Hamill, John F.

    2009-01-01

    The Grand Canyon of the Colorado River, one of the world's most spectacular gorges, is a premier U.S. National Park and a World Heritage Site. The canyon supports a diverse array of distinctive plants and animals and contains cultural resources significant to the region's Native Americans. About 15 miles upstream of Grand Canyon National Park sits Glen Canyon Dam, completed in 1963, which created Lake Powell. The dam provides hydroelectric power for 200 wholesale customers in six western States, but it has also altered the Colorado River's flow, temperature, and sediment-carrying capacity. Over time this has resulted in beach erosion, invasion and expansion of nonnative species, and losses of native fish. Public concern about the effects of Glen Canyon Dam operations prompted the passage of the Grand Canyon Protection Act of 1992, which directs the Secretary of the Interior to operate the dam 'to protect, mitigate adverse impacts to, and improve values for which Grand Canyon National Park and Glen Canyon National Recreation Area were established...' This legislation also required the creation of a long-term monitoring and research program to provide information that could inform decisions related to dam operations and protection of downstream resources.

  5. Comprehensive District Reform: Philadelphia's Grand Experiment.

    Useem, Elizabeth; Balfanz, Robert

    2002-01-01

    This report describes "Philadelphia's Grand Experiment" in comprehensive school district reform, from its conception through its initial months of implementation. In 2001, as part of the remedy for low student performance, the governor ordered the state to take over governance of the Philadelphia School District, with a substantial…

  6. Rio Branco, grand strategy and naval power

    João Paulo Alsina Jr.

    2014-12-01

    Full Text Available This article addresses Baron of Rio Branco's grand strategy and the role played by the naval reorganization program (1904-1910 in this context. The ensuing case study determined the domestic and international constraints that affected the program, as well as the worldview of the patron of Brazilian diplomacy regarding military power's instrumentality to foreign policy.

  7. Reisipakkumine - Grand Tour Itaalias / Mai Levin

    Levin, Mai, 1942-

    2009-01-01

    Tiina Abeli koostatud ja Urmas Viigi kujundatud näitus "Grand Tour. Eesti kunstnikud Itaalias" Kumu Kunstimuuseumis 05. aprillini. Loetletud eksponeeritud tööde autoreid. Näitus annab ülevaate, kes siinsetest kunstnikest 19. sajandi algusest kuni 1930ndate aastateni Itaalias käisid ja kuidas see nende loomingut mõjutas

  8. Middle Rio Grande Basin Research Report 2008

    Deborah M. Finch; Catherine Dold

    2008-01-01

    An ecosystem is rarely static. A natural system composed of plants, animals, and microorganisms interacting with an area's physical factors, an ecosystem is always fluctuating and evolving. But sometimes, often at the hands of humans, ecosystems change too much. Such is the case with many of the ecosystems of the Middle Rio Grande Basin of New Mexico.

  9. Panel - Rio Grande restoration: Future directions

    Deborah M. Finch; Pete V. Domenici; Jeffrey. C. Whitney; Steve Harris; Brian Shields; Clifford S. Crawford

    1996-01-01

    The purpose of this panel was to discuss historical and current changes to the Rio Grande system, focusing on the middle Basin, and to present and review different individual, organizational, and political perspectives on the future of the system. Invitations were made to panelists based on their past and current interests and activities pertaining to restoration of...

  10. Interim long-term surveillance plan for the Cheney disposal site near, Grand Junction, Colorado

    1997-08-01

    This interim long-term surveillance plan (LTSP) describes the U.S. Department of Energy's (DOE) long-term care program for the Uranium Mill Tailings Remedial Action (UMTRA) Project Cheney Disposal Site in Mesa County near Grand Junction, Colorado. This LSTP describes the long-term surveillance program the DOE will implement to ensure the Cheney disposal site performs as designed and is cared for in a manner that protects the public health and safety and the environment. Before each disposal site is licensed for custody and long-term care, the Nuclear Regulatory Commission (NRC) requires the DOE to submit such a site-specific LTSP

  11. Long-term surveillance plan for the Cheney disposal site near Grand Junction, Colorado

    1997-07-01

    This long-term surveillance plan (LTSP) describes the U.S. Department of Energy's (DOE) long-term care program for the Uranium Mill Tailings Remedial Action (UMTRA) Project Cheney Disposal Site near Grand Junction, Colorado. This LSTP describes the long-term surveillance program the DOE will implement to ensure the Cheney Disposal Site performs as designed and is cared for in a manner that protects the public health and safety and the environment. Before each disposal site is licensed for custody and long-term care, the Nuclear Regulatory Commission (NRC) requires the DOE to submit such a site-specific LTSP

  12. [The apothecaries of the Saint-Honoré district of Paris in the 17th century. The apothecaries Antoine and Jacques Grégoire and Louis XIII’s first painter, Simon Vouet].

    Warolin, Christian

    2016-12-01

    This article presents the biographies of the apothecaries who lived in the Rue Saint-Honoré in Paris in the 17th century. Two major facts emerge from this study. The first concerns the formation of a family network involving the apothecaries and the royal artists. The apothecaries Antoine and Jacques Grégoire became allied with Simon Vouet, the first painter of Louis XIII . Links were also made between Antoine Grégoire and Jacques Sarazin, the King’s sculptor, and then with Michel Corneille, painter to the King. The famous painting by Simon Vouet hanging in the assembly hall of the Faculty of Pharmacy in Paris is probably the fruit of his collaboration with Jacques Grégoire, his brother-in-law and an erudite botanist. The other notable fact concerns the relations between Anne de Furnes, widow of Antoine Brulon, the rich apothecary to the King Antoine Brulon, and Molière, both in Paris and in the village of Auteuil. The other notable fact concerns the relations between Anne de Furnes, widow of Antoine Brulon, the rich apothecary to the King Antoine Brulon, and Molière, both in Paris and in the village of Auteuil.

  13. Sfermion mass degeneracy, superconformal dynamics, and supersymmetric grand unified theories

    Kobayashi, Tatsuo; Noguchi, Tatsuya; Nakano, Hiroaki; Terao, Haruhiko

    2002-01-01

    We discuss issues in a scenario where hierarchical Yukawa couplings are generated through the strong dynamics of superconformal field theories (SCFTs). Independently of the mediation mechanism of supersymmetry breaking, the infrared convergence property of SCFTs can provide an interesting solution to the supersymmetric flavor problem; sfermion masses are suppressed around the decoupling scale of SCFTs and eventually become degenerate to some degree, thanks to family-independent radiative corrections governed by the gaugino masses of the minimal supersymmetric standard model (MSSM). We discuss under what conditions the degeneracy of the sfermion mass can be estimated in a simple manner. We also discuss the constraints from lepton flavor violations. We then explicitly study sfermion mass degeneracy within the framework of grand unified theories coupled to SCFTs. It is found that the degeneracy for right-handed sleptons becomes worse in the conventional SU(5) model than in the MSSM. On the other hand, in the flipped SU(5)xU(1) model, each right-handed lepton is still an SU(5) singlet, whereas the B-ino mass M 1 is determined by two independent gaugino masses of SU(5)xU(1). These two properties enable us to have an improved degeneracy for the right-handed sleptons. We also speculate on how further improvement can be obtained in the SCFT approach

  14. Cosmological implications of grand unified theories

    Nanopoulos, D.V.

    1982-01-01

    These lectures, mainly devoted to the cosmological implications of GUTs, also include the essential ingredients of GUTs and some of their important applications to particle physics. Section 1 contains some basic points concerning the structure of the standard strong and electroweak interactions prior to grand unification. A detailed expose of GUTs is attempted in sect. 2, including their basci principles and their consequences for particle physics. The minimal, simplest GUT, SU 5 is analysed in some detail and it will be used throughout these lectures as the GUT prototype. Finally, sect. 3 contains the most important cosmological implications of GUTs, including baryon number generation in the early Universe (in rather lengthy detail), dissipative processes in the very early Universe, grand unified monopoles, etc. (orig./HSI)

  15. The geology of Piz Pian Grand

    Huber, M.; Staeuble, J.

    1987-01-01

    Nagra has identified four potential sites for a repository for low- and intermediate-level waste. Exploration work is already underway at Oberbauenstock (UR) and Piz Pian Grand (GR). As part of the investigations in the Piz Pian Grand area, geological surface mapping was carried out between 1984 and 1987. Since the data obtained is still being evaluated, it would be premature to draw any interpretative conclusions at this stage. On the other hand, some of the most significant observations of this work can be summarised here. As a first step, the geological framework in which these investigations are to be seen should be defined. Observations will then be made on the rock content (lithology) and geometric structure (structural geology) of the area. (author) 6 figs

  16. Grand Gulf-prioritization of regulatory requirements

    Meisner, M.J.

    1993-01-01

    As cost pressures mount, Grand Gulf nuclear station (GGNS) is relying increasingly on various prioritization approaches to implement, modify, eliminate, or defer regulatory requirements. Regulatory requirements can be prioritized through the use of three measures: (1) safety (or risk) significance; (2) cost; and (3) public policy (or political) significance. This paper summarizes GGNS' efforts to implement solutions to regulatory issues using these three prioritization schemes to preserve a balance between cost and safety benefit

  17. Between two evils: Investors prefer grand corruption!

    Graf Lambsdorff, Johann

    2005-01-01

    Recent empirical studies claim that, in addition to levels of corruption, investors are deterred by its unpredictability. I claim instead that it is petty corruption that deters investors. I employ seven subcomponents of corruption for a sample of 102 countries that appear in the 2003 Global Competitiveness Report of the WEF. The second principal component of this data depicts a grand, political type, embracing corruption in government policymaking and in judicial decisions as opposed to corr...

  18. Grand Challenges in Music Information Research

    Goto, Masataka

    2012-01-01

    This paper discusses some grand challenges in which music information research will impact our daily lives and our society in the future. Here, some fundamental questions are how to provide the best music for each person, how to predict music trends, how to enrich human-music relationships, how to evolve new music, and how to address environmental, energy issues by using music technologies. Our goal is to increase both attractiveness and social impacts of music information research in the fut...

  19. Meliponiculture in Rio Grande do Norte

    Ulysses Madureira Maia

    2015-12-01

    Full Text Available ABSTRACT. Maia U.M., Jaffe R., Carvalho A.T. & Imperatriz-Fonseca V.L. [Meliponiculture in Rio Grande do Norte.] Meliponicultura no Rio Grande do Norte. Revista Brasileira de Medicina Veterinária, 37(4:327-333, 2015. Departamento de Biologia, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto, Universidade de São Paulo, Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto, SP 14040-901, Brasil. E-mail: ummaia@usp.br This study aimed to assess the current status of stingless bee beekeeping (meliponiculture in the State of Rio Grande do Norte, Brazil, with the aid of structured questionnaires made during visits to beekeepers. The results were compared with a previous census made in the state and with a similar study from Australia. Meliponiculture in Rio Grande do Norte is still informal and little standardized. The activity has grown in recent years considering the mean number of nests per beekeeper. Most apiaries are formed of up to 50 colonies, usually distributed in the backyards of homes. Twelve species of stingless bees were reared in the state, and the most common was the “Jandaíra” bee (Melipona subnitida, whose honey is considered medicinal. While many beekeepers already know the importance of bees as pollinators, stingless bees are still not used for crop pollination. Compared to a recent analysis of beekeeping in Australia, meliponiculture in Brazil is more traditional, honey is the main product and the number of colonies per beekeeper is much higher. Our results highlight the need to reinforce knowledge about bees and promote specific training aimed at improving and standardizing management practices.

  20. Neutrino mixing in a grand unified theory

    Milton, K.; Tanaka, K.

    1980-01-01

    Neutrino mixing in a grand unified theory in which the neutrino mass matrix is determined by the Gell-Mann-Ramond-Slansky mechanism was investigated. With an arbitrary real right-handed Majorana mass matrix which incorporates three neutrino mass scales, the effects of the up-quark mass matrix are found to be dominant and as a result no significant mixing of ν/sub e/ occurs, while ν/sub μ/ - ν/sub γ/ mixing can be substantial

  1. The Grand Strategy of Charles de Gaulle

    1989-09-08

    4. TITLE AND SUBTITLE The Grand Startegy of Charles de Gaulle 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...dependent on French influence within NATO and the Common Market . De Gaulle frequently used these fora to veto British and American initiatives. As Cook...the reserve currency. Gold would be the basis of international finance and a French-dominated European Common Market would provide the framework

  2. Silence and table manners: when environments activate norms.

    Joly, Janneke F; Stapel, Diederik A; Lindenberg, Siegwart M

    2008-08-01

    Two studies tested the conditions under which an environment (e.g., library, restaurant) raises the relevance of environment-specific social norms (e.g., being quiet, using table manners). As hypothesized, the relevance of such norms is raised when environments are goal relevant ("I am going there later") and when they are humanized with people or the remnants of their presence (e.g., a glass of wine on a table). Two studies show that goal-relevant environments and humanized environments raise the perceived importance of norms (Study 1) and the intention to conform to norms (Study 2). Interestingly, in both studies, these effects reach beyond norms related to the environments used in the studies.

  3. [Grand Banks activity : updates and opportunities

    Bruce, G.

    1998-01-01

    An overview of the exploration and on-going activities by the petroleum industry on the Grand Banks of Newfoundland was presented. The two offshore oil developments underway are Hibernia and Terra Nova, both located in the Jeanne d'Arc Basin. Current production from Hibernia is 68,000 bopd, expected to rise to 130,000 bopd in 1999. The Terra Nova Field is still under development. Total recoverable reserves from the 17 discoveries made in the Jeanne d'Arc Basin are estimated at 1.6 billion barrels of oil and 4 trillion cubic feet of gas. Industry participants in the area include Amoco, Petro-Canada, Mobil, Chevron, Husky and Norsk Hydro. Petro-Canada believes the Grand Banks represent one of the best opportunities for oil anywhere in the world. There are currently 21 exploration licenses held on the Grand Banks. Major attractions of the area include the large reserve potential, the relatively low finding costs, the size of the pools being discovered, improvements in offshore technology that have substantially lowered development costs, and a profit-sensitive generic royalty regime that ensures reasonable rates of return for investors. figs

  4. Proton decay in grand unified theories

    Lucha, W.

    1984-01-01

    Interactions which violate the conservation of baryon and lepton number represent an intrinsic part of all grand unified theories (GUTs) of strong and electroweak interactions. These new interactions - predicted within the framework of GUTs - generate B and L violating four-fermion interactions via the exchange of superheavy particles which cannot be ascribed a well-defined baryon or lepton number. The effective coupling constant of these four-fermion interactions might be large enough to make the proton decay detectable by the present generation of experiments. In this review the basic concepts of conventional as well as supersymmetric GUTs relevant for proton decay are sketched. The baryon number violating sector of grand unified theories is discussed in more detail. Special emphasis is laid on the various selection rules arising as consequences of low-energy gauge invariance and supersymmetry for proton decay. These selection rules already determine the coarse pattern of the resulting decay modes and branching ratios without any reference to or detailed knowledge of the underlying grand unified theory. Finally the numerous theoretical predictions are summarized and confronted with experiment. (Author)

  5. Raptor Use of the Rio Grande Gorge

    Ponton, David A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-03-20

    The Rio Grande Gorge is a 115 km long river canyon located in Southern Colorado (15 km) and Northern New Mexico (100 km). The majority of the canyon is under the administration of the Bureau of Land Management {BLM), and 77 km of the canyon south of the Colorado/New Mexico border are designated Wild River under the National Wild and Scenic Rivers Act of 1968. Visits I have made to the Rio Grande Gorge over the past 15 .years disclosed some raptor utilization. As the Snake River Birds of Prey Natural Area gained publicity, its similarity to the Rio Grande Gorge became obvious, and I was intrigued by the possibility of a high raptor nesting density in the Gorge. A survey in 1979 of 20 km of the northern end of the canyon revealed a moderately high density of red-tailed hawks and prairie falcons. With the encouragement of that partial survey, and a need to assess the impact of river-running on nesting birds of prey, I made a more comprehensive survey in 1980. The results of my surveys, along with those of a 1978 helicopter survey by the BLM, are presented in this report, as well as general characterization of the area, winter use by raptors, and an assessment of factors influencing the raptor population.

  6. Influence of manner of heating on functioning of fireplace

    Kouki, J.

    1994-01-01

    In connection with a bioenergy research programme, there is an ongoing project for developing of wood-fired fireplaces. The overall target in the project is through research and development to improve the combustion and heating characteristics of fireplaces so that their harmful flue gas emissions are reduced and they become more appropriate sources of supplementary and reserve energy (e.g. when installed in electrically heated houses). In connection with this project, TTS Institute's Forestry Department conducted a study on the heating properties of a lightweight iron stove. Correct manner of heating is a means to reducing the amount of harmful flue gases produced by fireplaces and of raising their combustion efficiency. The content of environmentally harmful gases in the flue gases was at Its maximum when the stove was operated with little draught and with the combustion chamber full of fuel. By increasing the draught from 4 Pa to 32 Pa, the carbon monoxide content of the non-combusted gases was reduced almost by 75 percent. This was accompanied by nearly a doubling of the free heat loss of the flue gases. As well as being influenced by the draught in the flue, the functioning of the stove and completeness of combustion was influenced by the moisture content of the chopped firewood. A rise in the moisture level from 13 % to 40 % led to nearly a fivefold increase in the proportion of combustible gases in the flue gases

  7. LEP constraints on grand unified theories

    Sarkar, Utpal

    1993-01-01

    Recent developments on grand unified theories (GUTs) in the context of the LEP measurements of the coupling constants are reviewed. The three coupling constants at the electroweak scale have been measured at LEP quite precisely. One can allow these couplings to evolve with energy following the renormalization group equations for the various groups and find out whether all the coupling constants meet at any energy. It was pointed out that the minimal SU(5) grand unified theory fails to satisfy this test. However, various extensions of the theory are still allowed. These extensions include (i) supersymmetric SU(5) GUT, with some arbitrariness in the susy breaking scale arising from the threshold corrections, (ii) non-susy SU(5) GUTs with additional fermions as well as Higgs multiplets, which has masses of the order of TeV, and (iii) non-renormalizable effect of gravity with a fine tuned relation among the coupling constants at the unification energy. The LEP results also constrain GUTs with an intermediate symmetry breaking scale. By adjusting the intermediate symmetry breaking scale, one usually can have unification, but these theories get constrained. For example, the left-right symmetric theories coming from GUTs can be broken only at energies higher than about ∼10 10 GeV. This implies that if right handed gauge bosons are found at energies lower than this scale, then that will rule out the possibility of grand unification. Another recent interesting development on the subject, namely, low energy unification, is discussed in this context. All the coupling constants are unified at energies of the order of ∼10 8 GeV when they are embedded in an SU(15)GUT, with some particular symmetry breaking pattern. But even in this case the results of the intermediate symmetry breaking scale remain unchanged. (author). 16 refs., 3 figs

  8. Maternal and fetal outcome in grand multipara

    Qamar, A.; Qamar, S.

    2015-01-01

    Study Design: Case control study. Place and Duration of Study: Gynecology and Obstetric Unit-I of the Jinnah Post Graduate and Medical Centre Karachi, from February 2009 to January 2010. Patients and Methods: One hundred (100) patients of grand multipara (GMP), (parity = 5) and 100 patients of multipara (MP) (parity 2-4) were included in the study. Pregnant women with known medical conditions including essential hypertension, diabetes mellitus, epilepsy, primigravidas, women with previous caesarean section and twin pregnancies were excluded. Patients were admitted through antenatal clinic and emergency. A detailed history was taken and a physical examination was done with special emphasis on obstetrical examination. Investigations like blood CP, Urine D/R, blood grouping and sonogram were done. During labour, mother and neonates were managed according to ward protocols. Maternal and fetal outcomes were compared among GMPs and MPs. Results: A high frequency of anaemia (81% vs 20%), pregnancy induced hypertension (45%, vs. 26%) and gestational diabetes (9%, vs1%) were seen in GMP as compared to MP group. Frequency of malpresentations (26% vs 15%), postpartum hemorrhage (15%, vs 10%) and intrauterine deaths (26%, vs 13%) were higher in GMP group along with a high caesarean delivery rate (GMP 21%, MP 14%). A higher maternal mortality (GMP 4%, MP 1%) and low APGAR score (GMP 12%, MP 4%) were observed among babies born to grand multipara group. Conclusion: Grand multiparity is associated with adverse outcome for both mother and fetus. Effort should be directed to reduce high parity in the community through effective family planning initiatives. Specialized antenatal and obstetrical care facilities should be available. (author)

  9. Lie groups and grand unified theories

    Gubitoso, M.D.

    1987-01-01

    This work presents some concepts in group theory and Lie algebras and, at same time, shows a method to study and work with semisimple Lie groups, based on Dynkin diagrams. The aproach taken is not completely formal, but it presents the main points of the elaboration of the method, so its mathematical basis is designed with the purpose of making the reading not so cumbersome to those who are interested only in a general picture of the method and its usefulness. At the end it is shown a brief review of gauge theories and two grand-unification models based on SO(13) and E 7 gauge groups. (author) [pt

  10. Grand Canonical Ensembles in General Relativity

    Klein, David; Yang, Wei-Shih

    2012-01-01

    We develop a formalism for general relativistic, grand canonical ensembles in space-times with timelike Killing fields. Using that, we derive ideal gas laws, and show how they depend on the geometry of the particular space-times. A systematic method for calculating Newtonian limits is given for a class of these space-times, which is illustrated for Kerr space-time. In addition, we prove uniqueness of the infinite volume Gibbs measure, and absence of phase transitions for a class of interaction potentials in anti-de Sitter space.

  11. Produccion de plantas grandes usando minicontenedores

    R. Kasten Dumroese; Thomas D. Landis

    2012-01-01

    En América del Norte hay cada vez más interés por la producción híbrida o mixta. La misma consiste en cultivar plantines en contenedores de pequeño volumen y luego trasplantarlos; el trasplante se puede realizar a canteros en el suelo como en la producción a raíz desnuda o bien a contenedores más grandes. Originalmente se llamaban plantines "plug+", "...

  12. [Perception manner of mother of obese persons in adolescence].

    Radoszewska, Joanna

    2007-01-01

    There are specific relation properties of mother to the obese child. The mother representation in child is understand as a experience manner of herself. Representation (mental image) include perceptions, knowledge about characteristics and behaviors of a person and evaluation and experiences that provoke in others. The aim of this article is a trial of an answer what is a mental representation of mother experienced by obese girls and boys in adolescence. 21 obese persons (12 girls and 9 boys) and 23 persons of normal body mass (15 girls and 8 boys) have been investigated. The mean age of the investigated obese persons were 14.53, and for a person of normal body mass was 15.31. All persons were investigated by a clinical interview with 6 questions concerning mental mother representation. The obtained results were analyzed in relation to mental mother representation contents: cognitive, emotional, social, sexual, certificate, behavioral and somatic. Obese persons more often than the person of the normal body mass identify to mental mother representation somatic contents, more rarely social, sexual and behavioral contents. Obese girls more rarely than girls of the normal body mass identify to social contents, more often to somatic. Obese girls more rarely than obese boys identify to mental mother representation emotional contents, more often to somatic contents. The specific relation properties of mother to obese person in adolescence could be manifested in difficulties in turn on contents of mental mother representation, in external, somatic point of concern for mental mother representation, difficulties in contact with mental contents of mother representation.

  13. The Grand Duchy on the Grand Tour: A Historical Study of Student Migration in Luxembourg

    Rohstock, Anne; Schreiber, Catherina

    2013-01-01

    Since Luxembourg became independent in 1839, practically the entire political, economic and intellectual elite of the country has been socialised abroad. It was only in 2003 that the Grand Duchy set up its own university; before then, young Luxembourgers had to study in foreign countries. Over the past 150 years, Luxembourg has thus experienced…

  14. 28 milliards d’euros, c’est grand comment ?

    Ozer, Pierre; Salmon, Marc; Theunissen, Yannick

    2009-01-01

    J’ouvre mon quotidien. Fortis : 28 milliards d’euros de pertes en 2008. Ma fille de sept ans qui commence à lire et pose sans cesse des questions sur tout me lance : « Dis-moi, papa : 28 milliards d’euros, c’est grand comment ? ». Grande question… Je réfléchis et tente de trouver une parade parlante pour un enfant qui, in fine, se pose les mêmes questions que les grandes personnes.

  15. Gamma ray and neutrino detector facility (GRANDE), Task C

    Sobel, H.W.; Yodh, G.B.

    1991-08-01

    GRANDE is an imaging, water Cerenkov detector, which combines in one facility an extensive air shower array and a high-energy neutrino detector. We proposed that the detector be constructed in phases, beginning with an active detector area of 31,000 m 2 (GRANDE-I) 2 and expanding to a final size of 100,000--150,00 m 2 . Some of the characteristics of GRANDE-I are discussed in this paper

  16. SO(10) supersymmetric grand unified theories

    Dermisek, Radovan

    The origin of the fermion mass hierarchy is one of the most challenging problems in elementary particle physics. In the standard model fermion masses and mixing angles are free parameters. Supersymmetric grand unified theories provide a beautiful framework for physics beyond the standard model. In addition to gauge coupling unification these theories provide relations between quark and lepton masses within families, and with additional family symmetry the hierarchy between families can be generated. We present a predictive SO(10) supersymmetric grand unified model with D 3 x U(1) family symmetry. The hierarchy in fermion masses is generated by the family symmetry breaking D 3 x U(1) → ZN → nothing. This model fits the low energy data in the charged fermion sector quite well. We discuss the prediction of this model for the proton lifetime in light of recent SuperKamiokande results and present a clear picture of the allowed spectra of supersymmetric particles. Finally, the detailed discussion of the Yukawa coupling unification of the third generation particles is provided. We find a narrow region is consistent with t, b, tau Yukawa unification for mu > 0 (suggested by b → sgamma and the anomalous magnetic moment of the muon) with A0 ˜ -1.9m16, m10 ˜ 1.4m16, m16 ≳ 1200 GeV and mu, M1/2 ˜ 100--500 GeV. Demanding Yukawa unification thus makes definite predictions for Higgs and sparticle masses.

  17. O conservadorismo patronal da grande imprensa brasileira

    Fonseca Francisco

    2003-01-01

    Full Text Available Através da análise da opinião dos editoriais dos quatro principais periódicos diários da grande imprensa, isto é, o Jornal do Brasil, O Globo, a Folha de S. Paulo e O Estado de S. Paulo - aqui considerados "aparelhos privados de hegemonia" -, este artigo procura desvendar os posicionamentos adotados perante a ordem social na Constituinte de 1987/1988, que também contribuem para compreender a reação à Consolidação das Leis do Trabalho. Observa-se, além do mais, as estratégias utilizadas para sua consecução. Conclui-se que, por mecanismos diversos, a grande imprensa contribuiu decisivamente para a introdução da agenda ideológica neoliberal no país, pois atuou de forma a "divulgar e vulgarizar" as idéias pertinentes a este ideário e de forma militantemente conservadora e patronal.

  18. Aprovechamiento de Salto Grande Argentina – Uruguay

    Bongiovanni, M.

    1979-12-01

    Full Text Available The power harnessing of Salto Grande will be the first common project carried out by two South American Countries and this will foster greater integration of both countries. The project involves the following: — One 39 m-high dam — Two hydroelectric power plants — One international bridge — One shipping canal The benefits to be obtained from the project include: increase and improvement of the waterway network; increase of electricity production; railways and highway tie-ups between both countries; industrial development; increased availability of irrigation water; new tourist resorts; increase of fishing resources.

    El aprovechamiento hidroeléctrico de Salto Grande será el primer aprovechamiento común a dos países sudamericanos, lo que permitirá una mayor integración entre ellos. Consta de las siguientes obras: _ una presa de 39 m de altura; _ dos centrales hidroeléctricas; _ un puente internacional; _ un canal de navegación, etc. Entre los beneficios que se obtendrán destacan: aumento y mejora de la red de navegación; aumento de la producción eléctrica; enlace de las vías de ferrocarril y carreteras entre los dos países; desarrollo industrial; aumento de la disponibilidad de agua de riego; creación de zonas de turismo, e incremento de la riqueza piscícola.

  19. La masa de los grandes impactores

    Parisi, M. G.; Brunini, A.

    Los planetas han sido formados fundamentalmente acretando masa a través de colisiones con planetesimales sólidos. La masa más grande de la distribución de planetesimales y las masas máxima y mínima de los impactores, han sido calculadas usando los valores actuales del período y de la inclinación de los planetas (Lissauer & Safronov 1991; Parisi & Brunini 1996). Recientes investigaciones han mostrado, que las órbitas de los planetas gigantes no han sufrido variaciones con el tiempo, siendo su movimiento regular durante su evolución a partir de la finalización de la etapa de acreción (Laskar 1990, 1994). Por lo tanto, la eccentricidad actual de los planetas gigantes se puede utilizar para imponer una cota máxima a las masas y velocidades orbitales de los grandes impactores. Mediante un simple modelo dinámico, y considerando lo arriba mencionado, obtenemos la cota superior para la masa del planetesimal más grande que impactó a cada planeta gigante al final de su etapa de acreción. El resultado más importante de este trabajo es la estimación de la masa máxima permitida para impactar a Júpiter, la cúal es ~ 1.136 × 10 -1, siendo en el caso de Neptuno ~ 3.99 × 10 -2 (expresada en unidades de la masa final de cada planeta). Además, fue posible obtener la velocidad orbital máxima permitida para los impactores como una función de su masa, para cada planeta. Las cotas obtenidas para la masa y velocidad de los impactores de Saturno y Urano (en unidades de la masa y velocidad final de cada planeta respectivamente) son casi las mismas que las obtenidas para Júpiter debido a que estos tres planetas poseen similar eccentricidad actual. Nuestros resultados están en buen acuerdo con los obtenidos por Lissauer & Safronov (1991). Estas cotas podrían ser utilizadas para obtener la distribución de planetesimales en el Sistema Solar primitivo.

  20. Local grand unification and string theory

    Nilles, Hans Peter; Vaudrevange, Patrick K.S.

    2009-09-01

    The low energy effective action of string theory depends strongly on the process of compactification and the localization of fields in extra dimensions. Explicit string constructions towards the minimal supersymmetric standard model (MSSM) reveal interesting results leading to the concept of local grand unification. Properties of the MSSM indicate that we might live at a special location close to an orbifold fixed point rather than a generic point in Calabi-Yau moduli space. We observe an enhancement of (discrete) symmetries that have various implications for the properties of the MSSM such as proton stability as well as solutions to the flavor problem, the m-problem and the strong CP-problem. (orig.)

  1. A unified grand tour of theoretical physics

    Lawrie, Ian D

    2013-01-01

    A Unified Grand Tour of Theoretical Physics invites its readers to a guided exploration of the theoretical ideas that shape our contemporary understanding of the physical world at the fundamental level. Its central themes, comprising space-time geometry and the general relativistic account of gravity, quantum field theory and the gauge theories of fundamental forces, and statistical mechanics and the theory of phase transitions, are developed in explicit mathematical detail, with an emphasis on conceptual understanding. Straightforward treatments of the standard models of particle physics and cosmology are supplemented with introductory accounts of more speculative theories, including supersymmetry and string theory. This third edition of the Tour includes a new chapter on quantum gravity, focusing on the approach known as Loop Quantum Gravity, while new sections provide extended discussions of topics that have become prominent in recent years, such as the Higgs boson, massive neutrinos, cosmological perturba...

  2. Introduction to Grand Unified Theories. 12

    Wali, K.C.

    1989-01-01

    This chapter presents an introduction into Grand Unified Theories. After a discussion of the general features to be expected in any such theory, and of the motivations for them, a detailed presentation of SU(5) theory is given. The group structures, particle multiplets, gauge and Higgs bosons are explained. The two stages of spontaneous symmetry breaking via the Higgs model, are calculated individually and in combination. Fermion mass matrices and relations between quark and lepton masses are derived. predictions of SU(5) theory, calculated using renormalization group methods, are derived. The chapter ends with discussions that bring together particle physics and cosmology, including the baryon asymmetry problem, phase transitions in the very early universe, and singularities like domain walls, vortex lines and monopoles. (author). 9 refs.; 4 figs.; 5 tabs

  3. Pitié pour les grandes villes !

    Jérôme Monnet

    1997-02-01

    Full Text Available Roger Caillois disait, en 1938, qu´il existe "une représentation de la grande ville, assez puissante sur les imaginations pour que jamais en pratique ne soit posée la question de son exactitude, créée de toute pièce par le livre, assez répandue néanmoins pour faire partie de l´atmosphère mentale collective et posséder par suite une certaine force de contrainte"(Le mythe et l´homme, p.156 [c´est lui qui souligne]. En 1996, la presse française a consacré dossiers et articles à "Habitat II...

  4. Preface to a GUT (Grand Unified Theory)

    Honig, W.

    1982-01-01

    A Grand Unified Theory (GUT) is proposed exhibiting relativistic invariance and based on a physical model for vacuum space consisting of the superposition of oppositely charged continuous fluids. Models for the photon, electron, neutrino, proton, etc., consist of separate unique variations in the relative densities of the fluids and their flow patterns. This GUT is also based on the use of transfinite axiomatic number forms and on a concept of metrical relativity which hopefully reconciles the many logical dichotomies in and between Special Relativity and Quantum Mechanics. These ideas result in a number of experimental proposals and predicted results which appear to be underivable from present paradigms, first among which is a physical model for the hidden variable of Quantum Mechanics. It is on these features that attention should rest. (Auth.)

  5. Higgsless grand unified theory breaking and trinification

    Carone, Christopher D.; Conroy, Justin M.

    2004-01-01

    Boundary conditions on an extra dimensional interval can be chosen to break bulk gauge symmetries and to reduce the rank of the gauge group. We consider this mechanism in models with gauge trinification. We determine the boundary conditions necessary to break the trinified gauge group directly down to that of the standard model. Working in an effective theory for the gauge-symmetry-breaking parameters on a boundary, we examine the limit in which the grand-unified theory-breaking-sector is Higgsless and show how one may obtain the low-energy particle content of the minimal supersymmetric standard model. We find that gauge unification is preserved in this scenario, and that the differential gauge coupling running is logarithmic above the scale of compactification. We compare the phenomenology of our model to that of four dimensional 'trinified' theories

  6. Grand unified models including extra Z bosons

    Li Tiezhong

    1989-01-01

    The grand unified theories (GUT) of the simple Lie groups including extra Z bosons are discussed. Under authors's hypothesis there are only SU 5+m SO 6+4n and E 6 groups. The general discussion of SU 5+m is given, then the SU 6 and SU 7 are considered. In SU 6 the 15+6 * +6 * fermion representations are used, which are not same as others in fermion content, Yukawa coupling and broken scales. A conception of clans of particles, which are not families, is suggested. These clans consist of extra Z bosons and the corresponding fermions of the scale. The all of fermions in the clans are down quarks except for the standard model which consists of Z bosons and 15 fermions, therefore, the spectrum of the hadrons which are composed of these down quarks are different from hadrons at present

  7. Review of freeboard: Grand Rapids Generating Station

    Groeneveld, J.L.; Harding, W.B.; Bonin, D.V.; Fuchs, D.M. [Acres Manitoba Ltd., Winnipeg, MB (Canada); Warner, B.J. [Manitoba Hydro, Winnipeg, MB (Canada)

    2001-10-01

    Constructed during the period 1960-1965, the Grand Rapids Generating Station is a 472 MW hydroelectric station located approximately 400 kilometres northwest of Winnipeg, Manitoba, on the Saskatchewan River. An intake structure, four penstocks, a four-unit plus house unit powerhouse, wing walls, extensive dyke structures and a four-bay spillway are the components of the generating station. A little over ten years ago, the Manitoba Hydro Dam Safety Program was initiated. The program included a detailed dam safety review of the Grand rapids Generating Station. A potential deficiency in the freeboard allowance for several of the earthen dykes was revealed by the review process. The dam safety guidelines sponsored by the Canadian Dam Association were not met. The occurrence of a 1:1000 year wind event from the critical direction when the reservoir was at or near its full supply level was compounded by the analysis. The establishment of a wind and wave monitoring program was included in the deficiency studies commissioned. The objective was to confirm the empirical estimates concerning wave height, the development and usage of a two dimensional numerical wave model, and additional freeboard analyses to refine estimates of the recurrence interval of the current level of protection. A statistical Monte Carlo analysis was performed in the case of the estimates of the recurrence interval to determine the joint probabilities of seasonal variations in wind direction, wind speed, and reservoir level. The estimate of the actual risk of overtopping was therefore refined, and the details pertaining to the methodology and the conclusions of the analysis are all included in the paper. 15 refs., 4 tabs., 9 figs.

  8. Perspective view over the Grand Canyon, Arizona

    2001-01-01

    This simulated true color perspective view over the Grand Canyon was created from Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) data acquired on May 12, 2000. The Grand Canyon Village is in the lower foreground; the Bright Angel Trail crosses the Tonto Platform, before dropping down to the Colorado Village and then to the Phantom Ranch (green area across the river). Bright Angel Canyon and the North Rim dominate the view. At the top center of the image the dark blue area with light blue haze is an active forest fire. ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products. The broad spectral coverage and high spectral resolution of ASTER provides scientists in numerous disciplines with critical information for surface mapping, and monitoring of dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance. The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate. Size: 5 km in foreground to 40 km Location: 36.3 degrees north latitude, 112 degrees west longitude Orientation: North-northeast at top Original Data Resolution: ASTER 15 meters Dates Acquired: May 12, 2000

  9. Phase transitions at finite chemical potential in grand unified theories

    Bailin, D.; Love, A.

    1984-01-01

    We discuss the circumstances in which non-zero chemical potentials might prevent symmetry restoration in phase transitions in the early universe at grand unification or partial unification scales. The general arguments are illustrated by consideration of SO(10) and SU(5) grand unified theories. (orig.)

  10. Fetal Outcomes among Grand Multiparous and Multiparous Women ...

    Objective: To compare fetal outcomes among grand multiparous (para 5-9) and multiparous (para 2-4) delivering in Mulago hospital, Uganda. Design: Prospective cohort study. Setting: Mulago hospital, Uganda. Subjects: One hundred and fifty six grand multiparous and multiparous women were recruited on admission in ...

  11. First report of Phytophthora ramorum infecting grand fir in California

    K.L. Riley; G.A. Chastagner

    2011-01-01

    Phytophthora ramorum was detected on grand fir in 2003 and 2005 in a Christmas tree plantation near Los Gatos, CA, in association with infected California bay laurel. Isolates derived from stem lesions were used to inoculate grand fir seedlings in two tests. Isolations from lesions on inoculated plants were positive for P. ramorum...

  12. Plants, arthropods, and birds of the Rio Grande [chapter 7

    Deborah M. Finch; Gale L. Wolters; Wang Yong; Mary Jean Mund

    1995-01-01

    Human populations have increased dramatically along the Rio Grande since European settlement. Human use of water for irrigation and consumption, and human use of land for agriculture, urban centers, livestock grazing, and recreation have changed Rio Grande ecosystems by altering flood cycles, channel geomorphology, upslope processes, and water quality and quantity....

  13. Research of the Rio Grande Ecosystem Management Program

    Deborah M. Finch

    2000-01-01

    This paper describes the mission, objectives, and preliminary results of the Middle Rio Grande Ecosystem Management Research Program managed at the Rocky Mountain Research Station's Albuquerque laboratory. This program was initiated in 1994 to address growing pressures to effectively manage the limited resources of the middle Rio Grande Basin. The program is...

  14. Elastoplasticidad anisotropa de metales en grandes deformaciones

    Caminero Torija, Miguel Angel

    El objetivo de este trabajo es el desarrollo de modelos y algoritmos numericos que simulen el comportamiento del material bajo estas condiciones en el contexto de programas de elementos finitos, dando como resultado predicciones mas precisas de los procesos de conformado y deformacion plastica en general. Para lograr este objetivo se han desarrollado diversas tareas destinadas a mejorar las predicciones en tres aspectos fundamentales. El primer aspecto consiste en la mejora de la descripcion del endurecimiento cinematico anisotropo en pequenas deformaciones, lo cual se ha realizado a traves de modelos y algoritmos implicitos de superficies multiples. Ha sido estudiada la consistencia de este tipo de modelos tanto si estan basados en una regla implicita similar a la de Mroz o en la regla de Prager. Ademas se han simulado los ensayos de Lamba y Sidebottom, obteniendo, en contra de la creencia general, muy buenas predicciones con la regla de Prager. Dichos modelos podrian ser extendidos de forma relativamente facil para considerar grandes deformaciones a traves de procedimientos en deformaciones logaritmicas, similares a los desarrollados en esta tesis y detallados a continuacion. El segundo aspecto consiste en la descripcion de la anisotropia elastoplastica inicial. Esto se ha conseguido mediante el desarrollo de modelos y algoritmos para plasticidad anisotropa en grandes deformaciones, bien ignorando la posible anisotropia elastica, bien considerandola simultaneamente con la anisotropia plastica. Para ello ha sido necesario desarrollar primero un nuevo algoritmo de elastoplasticidad anisotropa en pequenas deformaciones consistentemente linealizado y sin despreciar ningun termino, de tal forma que se conserve la convergencia cuadratica de los metodos de Newton. Este algoritmo en pequenas deformaciones ha servido para realizar la correccion plastica de dos algoritmos en grandes deformaciones. El primero de estos algoritmos es una variacion del clasico algoritmo de

  15. The Generating Mechanism of the Perlocutionary Effects of Train Manner Posters

    水田, 洋子

    2013-01-01

    Manner posters, which are used for the purpose of improving people’s manners in public spaces, attempt to be effective without being impositional. How do they meet the challenge? Manner posters can be considered to perform speech acts with written words and visual devices. The current work investigates the generating mechanism of their perlocutionary effects such as persuasion. It provides a case study of Japanese train manner posters by Tokyo Metro in 2008-2010. The analysis is conducted wit...

  16. 48 CFR 1371.101 - Inspection and manner of doing work.

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Inspection and manner of... DEPARTMENT SUPPLEMENTAL REGULATIONS ACQUISITIONS INVOLVING SHIP CONSTRUCTION AND SHIP REPAIR Provisions and Clauses 1371.101 Inspection and manner of doing work. Insert clause 1352.271-70, Inspection and Manner of...

  17. 45 CFR 1621.4 - Complaints by clients about manner or quality of legal assistance.

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Complaints by clients about manner or quality of...) LEGAL SERVICES CORPORATION CLIENT GRIEVANCE PROCEDURES § 1621.4 Complaints by clients about manner or... clients about the manner or quality of legal assistance that has been rendered by the recipient to the...

  18. Albuquerque/Middle Rio Grande Urban Waters Viewer

    These data have been compiled in support of the Middle Rio Grande/Albuquerque Urban Waters Partnership for the region including Albuquerque, New Mexico.The Middle Rio Grande/Albuquerque Urban Waters Federal Partnership is co-chaired by the U.S. Dept. of Housing and Urban Development and the U.S. Environmental Protection Agency. There are also a number of other federal agencies engaged in projects with Tribal, State, and local officials, and community stakeholders. Like many western river ecosystems, the Middle Rio Grande faces numerous challenges in balancing competing needs within a finite water supply and other resource constrains. Historical practices by our ancestors and immigrants to the Middle Rio Grande have established the conditions that we have inherited. Long-term drought exacerbated by climate change is changing conditions that affect natural and human communities as we strive to improve our precious Rio Grande.The Middle Rio Grande/Albuquerque Urban Waters Federal Partnership will reconnect our urban communities, particularly those that are overburdened or economically distressed, with the waterway by improving coordination among federal agencies and collaborating with community-led revitalization efforts. Our projects will improve our community water systems and promote their economic, environmental and social benefits. Specifically, the Middle Rio Grande/Albuquerque Urban Waters Federal Partnership will support the development of the Valle de Oro

  19. Grand Fir Nutrient Management in the Inland Northwestern USA

    Dennis R. Parent

    2016-11-01

    Full Text Available Grand fir (Abies grandis (Douglas ex D. Don Lindley is widely distributed in the moist forests of the Inland Northwest. It has high potential productivity, its growth being nearly equal to western white pine, the most productive species in the region. There are large standing volumes of grand fir in the region. Nutritionally, the species has higher foliage cation concentrations than associated conifers, especially potassium (K and calcium (Ca. In contrast, it has lower nitrogen (N foliage concentrations, which creates favorable nutrient balance on N-limited sites. Despite concentration differences, grand fir stores proportionally more nutrients per tree than associated species because of greater crown biomass. Although few fertilization trials have examined grand fir specifically, its response is inferred from its occurrence in many monitored mixed conifer stands. Fertilization trials including grand fir either as a major or minor component show that it has a strong diameter and height growth response ranging from 15% to 50% depending in part on site moisture availability and soil geology. Grand fir tends to have a longer response duration than other inland conifers. When executed concurrently with thinning, fertilization often increases the total response. Late rotation application of N provides solid investment returns in carefully selected stands. Although there are still challenges with the post-fertilization effects on tree mortality, grand fir will continue to be an important species with good economic values and beneficial responses to fertilization and nutrient management.

  20. Proton decay: Numerical simulations confront grand unification

    Brower, R.C.; Maturana, G.; Giles, R.C.; Moriarty, K.J.M.; Samuel, S.

    1985-01-01

    The Grand Unified Theories of the electromagnetic, weak and strong interactions constitute a far reaching attempt to synthesize our knowledge of theoretical particle physics into a consistent and compelling whole. Unfortunately, many quantitative predictions of such unified theories are sensitive to the analytically intractible effects of the strong subnuclear theory (Quantum Chromodynamics or QCD). The consequence is that even ambitious experimental programs exploring weak and super-weak interaction effects often fail to give definitive theoretical tests. This paper describes large-scale calculations on a supercomputer which can help to overcome this gap between theoretical predictions and experimental results. Our focus here is on proton decay, though the methods described are useful for many weak processes. The basic algorithms for the numerical simulation of QCD are well known. We will discuss the advantages and challenges of applying these methods to weak transitions. The algorithms require a very large data base with regular data flow and are natural candidates for vectorization. Also, 32-bit floating point arithmetic is adequate. Thus they are most naturally approached using a supercomputer alone or in combination with a dedicated special purpose processor. (orig.)

  1. Coordinating the Atlantis Grand Opening Event

    Smith, Abigail Allaine

    2013-01-01

    While working as the marketing intern for Kennedy Space Center's (KSC) Center Planning and Development Directorate (CPD), I was given the opportunity not only to learn new skills and expand my work experience under the powerful influence of NASA, but I also was given the opportunity to prove that I am an individual capable of contributing to the KSC team. My main responsibility while working in CPD was to organize and run a booth that represented the entire directorate at the Grand Opening of the Shuttle Atlantis exhibit during the weekend of June 28-30. This event was important for CPD because as a Directorate that markets KSC's facilities, technical capabilities and technologies to potential partners, it is important to attend all events and use them to gain an understanding of our audience. Although we catered mostly to the general public during this event, it was still important to reach out to the larger space enthusiast community and let them know about KSC's future plans to become a multi-user spaceport and that teclmology is still being developed.

  2. The grand descent has begun for CMS

    2006-01-01

    Until recently, the CMS experimental cavern looked relatively empty; its detector was assembled entirely at ground level, to be lowered underground in 15 sections. On 2 November, the first hadronic forward calorimeter led the way with a grand descent. The first section of the CMS detector (centre of photo) arriving from the vertical shaft, viewed from the cavern floor. There is something unusual about the construction of the CMS detector. Instead of being built in the experimental cavern, like all the other detectors in the LHC experiments, it was constructed at ground level. This was to allow for easy access during the assembly of the detector and to minimise the size of the excavated cavern. The slightly nerve-wracking task of lowering it safely into the cavern in separate sections came after the complete detector was successfully tested with a magnetic field at ground level. In the early morning of 2 November, the first section of the CMS detector began its eagerly awaited descent into the underground ca...

  3. Local grand unification in the heterotic landscape

    Schmidt, Jonas

    2009-06-01

    We consider the possibility that the unification of the electroweak interactions and the strong force arises from string theory, at energies significantly lower than the string scale. As a tool, an effective grand unified field theory in six dimensions is derived from an anisotropic orbifold compactification of the heterotic string. It is explicitly shown that all anomalies cancel in the model, though anomalous Abelian gauge symmetries are present locally at the boundary singularities. In the supersymmetric vacuum additional interactions arise from higher-dimensional operators. We develop methods that relate the couplings of the effective theory to the location of the vacuum, and find that unbroken discrete symmetries play an important role for the phenomenology of orbifold models. An efficient algorithm for the calculation of the superpotential to arbitrary order is developed, based on symmetry arguments. We furthermore present a correspondence between bulk fields of the orbifold model in six dimensions, and the moduli fields that arise from compactifying four internal dimensions on a manifold with non-trivial gauge background. (orig.)

  4. Gauge hierarchy problem in grand unified theories

    Alhendi, H.A.A.

    1982-01-01

    In grand unification schemes, several mass scales are to be introduced, with some of them much larger than all the others, to cope with experimental observations, in which elementary particles of higher masses require higher energy to observe them than elementary particles of lower masses. There have been controversial arguments in the literature on such hierarchical scale structure, when radiative corrections are taken into account. It has been asserted that the gauge hierarchy depends on the choice of the subtraction point (in the classical field space), of the four-point function at zero external momentum. It also has been asserted that the gauge hierarchy problem whenever it is possible to be maintained in one sector of particles, it also is possible to be maintained in the other sectors. These two problems have been studied in a prototype model, namely an 0(3)-model with two triplets of real scalar Higgs fields. Our analysis shows that, within ordinary perturbation theory, none of these two problems is quite correct

  5. Integrated telemedicine workstation for intercontinental grand rounds

    Willis, Charles E.; Leckie, Robert G.; Brink, Linda; Goeringer, Fred

    1995-04-01

    The Telemedicine Spacebridge to Moscow was a series of intercontinental sessions sponsored jointly by NASA and the Moscow Academy of Medicine. To improve the quality of medical images presented, the MDIS Project developed a workstation for acquisition, storage, and interactive display of radiology and pathology images. The workstation was based on a Macintosh IIfx platform with a laser digitizer for radiographs and video capture capability for microscope images. Images were transmitted via the Russian Lyoutch Satellite which had only a single video channel available and no high speed data channels. Two workstations were configured -- one for use at the Uniformed Services University of Health Sciences in Bethesda, MD. and the other for use at the Hospital of the Interior in Moscow, Russia. The two workstations were used may times during 16 sessions. As clinicians used the systems, we modified the original configuration to improve interactive use. This project demonstrated that numerous acquisition and output devices could be brought together in a single interactive workstation. The video images were satisfactory for remote consultation in a grand rounds format.

  6. Grand unification in the projective plane

    Hebecker, A.

    2004-01-01

    A 6-dimensional grand unified theory with the compact space having the topology of a real projective plane, i.e., a 2-sphere with opposite points identified, is considered. The space is locally flat except for two conical singularities where the curvature is concentrated. One supersymmetry is preserved in the effective 4d theory. The unified gauge symmetry, for example SU(5), is broken only by the non-trivial global topology. In contrast to the Hosotani mechanism, no adjoint Wilson-line modulus associated with this breaking appears. Since, locally, SU(5) remains a good symmetry everywhere, no UV-sensitive threshold corrections arise and SU(5)-violating local operators are forbidden. Doublet-triplet splitting can be addressed in the context of a 6d N=2 super Yang-Mills theory with gauge group SU(6). If this symmetry is first broken to SU(5) at a fixed point and then further reduced to the standard model group in the above non-local way, the two light Higgs doublets of the MSSM are predicted by the group-theoretical and geometrical structure of the model. (author)

  7. y las grandes ciudades: 1970-2004

    Adrián de León Arias

    2008-01-01

    Full Text Available El cambio regional en las manufacturas mexicanas a partir de la década de 1980 se ha caracterizado por el rápido crecimiento del empleo y la producción en la frontera norte del país y la pérdida de participación de ellos en las grandes ciudades. En este artículo se analiza y evalúa este cambio regional en términos de la dinámica de la productividad laboral y factorial total para ambas configuraciones espaciales, presentando cálculos de productividad para éstas de 1970 a 2004, estimados a partir de la información censal. Los resultados sugieren que mientras el empleo ha crecido en magnitud mucho más rápido en la frontera norte, esta dinámica se ha generado con bajos niveles en crecimiento de la productividad, al menos hasta fechas recientes, por lo que el cambio regional estimulado por la apertura comercial hasta 2004 no parece haber facilitado un crecimiento económico más acelerado para México

  8. Local grand unification in the heterotic landscape

    Schmidt, Jonas

    2009-07-15

    We consider the possibility that the unification of the electroweak interactions and the strong force arises from string theory, at energies significantly lower than the string scale. As a tool, an effective grand unified field theory in six dimensions is derived from an anisotropic orbifold compactification of the heterotic string. It is explicitly shown that all anomalies cancel in the model, though anomalous Abelian gauge symmetries are present locally at the boundary singularities. In the supersymmetric vacuum additional interactions arise from higher-dimensional operators. We develop methods that relate the couplings of the effective theory to the location of the vacuum, and find that unbroken discrete symmetries play an important role for the phenomenology of orbifold models. An efficient algorithm for the calculation of the superpotential to arbitrary order is developed, based on symmetry arguments. We furthermore present a correspondence between bulk fields of the orbifold model in six dimensions, and the moduli fields that arise from compactifying four internal dimensions on a manifold with non-trivial gauge background. (orig.)

  9. Constraints on grand unified superstring theories

    Ellis, J.; Lopez, J.L.; Nanopoulos, D.V.; Houston Advanced Research Center

    1990-01-01

    We evaluate some constraints on the construction of grand unified superstring theories (GUSTs) using higher level Kac-Moody algebras on the world-sheet. In the most general formulation of the heterotic string in four dimensions, an analysis of the basic GUST model-building constraints, including a realistic hidden gauge group, reveals that there are no E 6 models and any SO(10) models can only exist at level-5. Also, any such SU(5) models can exist only for levels 4≤k≤19. These SO(10) and SU(5) models risk having many large, massless, phenomenologically troublesome representations. We also show that with a suitable hidden sector gauge group, it is possible to avoid free light fractionally charged particles, which are endemic to string derived models. We list all such groups and their representations for the flipped SU(5)xU(1) model. We conclude that a sufficiently binding hidden sector gauge group becomes a basic model-building constraint. (orig.)

  10. A unified grand tour of theoretical physics

    Griffiths, J

    2002-01-01

    Anyone offering a grand tour is faced with several options. Should they concentrate on what may be considered to be essential features, or should they attempt to present a brief glimpse of almost everything? The present offering is a compromise between these two extremes. The area considered - theoretical physics - is now such a vast subject that some kind of compromise is essential. Indeed, the field is now so wide that few could even attempt to review it in a single-authored work. My task here is to assess how well this book has succeeded in its main aim of providing a unified (though introductory) tour of this subject. Constrained within a single volume, this is clearly not an updated Landau-Lifschitz. It cannot be expected to take any particular topic to the level of recent research. Nevertheless, it does seem to cover the broad range of essential topics which now constitute the subject. It starts (most appropriately in my opinion) with geometry. It then covers classical physics, general relativity and qu...

  11. Verona/Milano, andata e ritorno. Appunti sulla presenza dei pittori veronesi a Milano nel XIX secolo / Verona/Milano, there and back. Notes on Verona’s painters in Milan in the 19th Century

    Elena Casotto

    2013-11-01

    due città ha delle ripercussioni anche sul linguaggio artistico dei veronesi, il quale si differenzia dalla restante arte veneta – in massima parte influenzata dalla tradizione veneziana – proprio per una certa affinità con la pittura lombarda.   The study aims to illustrate (when it is possible also through artists’ writings the stories of the Verona’s painters who, in the nineteenth century, seek their fortune in Milan, which was the most updated artistic center in North Italy, especially beaucase of its Academy and its frequented exhibitions. This "migration" occurs because, during the Hapsburg’s rule (1815 - 1866, Verona becomes the pivot of the military system of the Regno Lombardo - Veneto and, consequently, the development of the city is subordinated to the needs of the military companies that stay or transit through its territory. Therefore military buildings and the means for long distance communications are increased, but the development of the city and the creation of small industries and businesses, that can help Verona’s people, are disregarded. In this situation, the art market is slack, both for the lack of public and private buyers, and for the few exhibitions organized during these difficult years. Also the Verona’s Academy experiences hard tiemes, due to outdated teaching methods and to the lack of money: in this situation the quality of teaching gets worse, so the artists, who have studied at this school, are unprepared to compete with painters coming from other italian Academies. After the unification of Italy and especially after the reform of the School of fine art of Verona (1873, the relationship between Verona and Milan becomes more complex: not only Verona’s painters go to Milan for studing and exhibiting their works of art, but also the authors from Lombardia do not disdain the shows of the Venetian city and even they aim at the direction of Verona’s Academy. Finally, it should be noted that the link between the two

  12. VT Built Up Lands in Grand Isle County - 1986

    Vermont Center for Geographic Information — (Link to Metadata) NRCS mapped historical and current-day built-up lands for Grand Isle County, VT using several vintages of aerial photography: 1941, 1962, 1974,...

  13. VT Built Up Lands in Grand Isle County - 1941

    Vermont Center for Geographic Information — (Link to Metadata) NRCS mapped historical and current-day built-up lands for Grand Isle County, VT using several vintages of aerial photography: 1941, 1962, 1974,...

  14. Constructing 5d orbifold grand unified theories from heterotic strings

    Kobayashi, Tatsuo; Raby, Stuart; Zhang Renjie

    2004-01-01

    A three-generation Pati-Salam model is constructed by compactifying the heterotic string on a particular T 6 /Z 6 Abelian symmetric orbifold with two discrete Wilson lines. The compactified space is taken to be the Lie algebra lattice G 2 -bar SU(3)-bar SO(4). When one dimension of the SO(4) lattice is large compared to the string scale, this model reproduces many features of a 5d SO(10) grand unified theory compactified on an S 1 /Z 2 orbifold. (Of course, with two large extra dimensions we can obtain a 6d SO(10) grand unified theory.) We identify the orbifold parities and other ingredients of the orbifold grand unified theories in the string model. Our construction provides a UV completion of orbifold grand unified theories, and gives new insights into both field theoretical and string theoretical constructions

  15. 27 CFR 9.119 - Middle Rio Grande Valley.

    2010-04-01

    ... Middle Rio Grande Valley. (a) Name. The name of the viticultural area described in this section is... 1979. (24) Veguita, N. Mex. (1952), revised 1979. (25) Wind Mesa, N. Mex. (1952), revised 1967. (c...

  16. A GRAND PLAN FOR EARTH LOVE EDUCATION IN SOUTHERN ...

    cognition. From this doubtful synthesis, the researcher appears to have constructed a grand theory of how the world without ... problem here is that all of the students (English. Xhosa and ..... accompanying 'earthy music' will contrihute to.

  17. Casa Grande Ruins National Monument acoustical monitoring 2010

    2014-11-01

    During September 2010, The Volpe Center collected baseline acoustical data at Casa Grande National Monument (CAGR), at one site for 28 days. The baseline data collected during this period will help park managers and planners estimate the effects of f...

  18. Flocculent and grand design spiral arm structure in cluster galaxies

    Elmegreen, D.M.

    1982-01-01

    A total of 829 spiral galaxies in 22 clusters having redshifts between z = 0.02 and 0.06 were classified according to the appearance of their spiral arm structures. The fraction of galaxies that have a grand design spiral structure was found to be higher among barred galaxies than among non-barred galaxies (at z = 0.02, 95 per cent of strongly barred galaxies have a grand design, compared with 67 per cent of non-barred or weakly barred galaxies). Cluster galaxies and distant non-cluster galaxies have the same fraction of grand design galaxies when resolution effects are considered. The grand design fraction among cluster galaxies is also similar to the fraction observed among nearby galaxies in binary systems and in groups. (author)

  19. Albuquerque/Middle Rio Grande Urban Waters Viewer

    U.S. Environmental Protection Agency — These data have been compiled in support of the Middle Rio Grande/Albuquerque Urban Waters Partnership for the region including Albuquerque, New Mexico.The Middle...

  20. Nalisis Kinerja Keuangan pada PT. Grand Victoria Hotel di Samarinda

    -, Atmajaya -

    2013-01-01

    Based on the results of analysis show that the performance of PT. Hotel Grand Victorian is measured using liquidity ratios and profitability ratios decreased from 2010-2012. Performance PT. Grand Victorian is measured using the liquidity ratio has decreased from year 2010-2012 consists of current ratio has decreased, and this is because the total current assets has increased and decreased. Meanwhile, the cash ratio from year 2010-2012 has increased, this is because the total cash and cash equ...

  1. Simulations of Precipitation Variability over the Upper Rio Grande Basin

    Costigan, Keeley R.; Bossert, James E.; Langley, David L.

    1997-10-01

    In this research, we study Albuquerque's water and how it may be affected by changes in the regional climate, as manifested by variations in Rio Grande water levels. To do this, we rely on the use of coupled atmospheric, runoff, and ground water models. Preliminary work on the project has focused on uncoupled simulations of the aquifer beneath Albuquerque and winter precipitation simulations of the upper Rio Grande Basin. The latter is discussed in this paper

  2. Restrictions on SU(5) as a grand unified theory

    Shellard, R.C.

    1984-01-01

    Some restrictions imposed upon Grand Unified Theories by dynamical symetry breakdown are examined. They are shown that, in particular, theories SU(5) as symmetry group, with 3 or more fermion families undergo dynamical symmetry breakdown, and some of the fermions will acquire mass at the Grand Unified scale. On the other hand, the SO(10) group, with 3 families is free from this problem. (Author) [pt

  3. Tres grandes plataformas marinas Mar del Norte

    Soulas, R.

    1978-03-01

    Full Text Available This article analyzes the different building stages of three large sea platforms. After studying the structure's main characteristics, preparing scale models and calculating ail the elements, platform construction was carried out in three stages: — Dry-dock construction of the hull base. — Installation in the water and finishing the structure. — Immersion and bridge installation. Finally, the necessary operations to move the platform to its definite location were carried out. The structures are formed by a parallelepiped hull of reinforced concrete, divided into compartments by means of vertical orthogonals panels on top of which 2 or 4 piles are placed to support the bridge.

    En este artículo se analizan las diversas etapas en la realización de tres grandes plataformas marinas. Después de un estudio de las características principales de la estructura, ensayos en modelo reducido y cálculo de todos los elementos, se procede a la construcción de las plataformas en tres fases: — Construcción en seco de la base del casco. — Colocación en el agua y acabado de la estructura. — Inmersión y colocación del puente. Por último, se realizan las operaciones necesarias para llevar la plataforma a su ubicación definitiva. Las estructuras están formadas por un casco paralelepipédico de hormigón armado, dividido en compartimientos mediante tabiques verticales ortogonales y sobre el que se han colocado 2 ó 4 pilas que soportan el puente.

  4. 26 CFR 1.669(b)-2 - Manner of exercising election.

    2010-04-01

    ... 26 Internal Revenue 8 2010-04-01 2010-04-01 false Manner of exercising election. 1.669(b)-2 Section 1.669(b)-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED... Years Beginning Before January 1, 1969 § 1.669(b)-2 Manner of exercising election. (a) By whom election...

  5. 26 CFR 301.6316-5 - Manner of paying tax by foreign currency.

    2010-04-01

    ... currency to be deposited shall be that amount which, when converted at the rate of exchange used on the... 26 Internal Revenue 18 2010-04-01 2010-04-01 false Manner of paying tax by foreign currency. 301....6316-5 Manner of paying tax by foreign currency. (a) Time and place to pay. The unpaid tax required to...

  6. Point of View: Manner of Realising The Matter in Adichie's Half of A ...

    manner' to create meaning or matter. The best form of art is the blending of form and content; means and end; manner and matter. Therefore, the uniqueness of any novelist's product is contingent upon how well or otherwise their peculiar ...

  7. 26 CFR 1.871-1 - Classification and manner of taxing alien individuals.

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Classification and manner of taxing alien... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Nonresident Aliens and Foreign Corporations § 1.871-1 Classification and manner of taxing alien individuals. (a) Classes of aliens. For purposes of the income tax...

  8. 26 CFR 1.522-2 - Manner of taxation of cooperative associations subject to section 522.

    2010-04-01

    ... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Manner of taxation of cooperative associations subject to section 522. 1.522-2 Section 1.522-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF...-2 Manner of taxation of cooperative associations subject to section 522. (a) In general. Farmers...

  9. Enterotoxemia em caprinos no Rio Grande do Sul Caprine enterotoxaemia in Rio Grande do Sul, Brazil

    Edson M. Colodel

    2003-12-01

    Full Text Available São descritos surtos de enterotoxemia em caprinos em cinco propriedades no Estado do Rio Grande do Sul. Os animais afetados eram, normalmente, encontrados mortos ou apresentavam evolução aguda de 2 a 3 horas com acentuada depressão, cólicas abdominais e diarréia profusa com fibrina. Em duas propriedades relataram-se casos com a evolução de até 12 horas. Em treze animais necropsiados observaram-se aumento de líquidos nas cavidades abdominal, torácica e pericárdica, congestão e hiperemia da serosa e mucosa do intestino, conteúdo do cólon líquido com fibrina além de hemorragias de serosa e fibrina. Em um animal constatou-se microangiopatia cerebral caracterizada por acúmulo de material homogêneo e eosinofílico no espaço perivascular. No conteúdo intestinal, colônias com bastonetes morfológica e bioquimicamente sugestivos de Clostridium perfringens foram caracterizadas no estudo bacteriológico. A soroneutralização em camundongos com conteúdo intestinal dos animais afetados, revelou a presença da toxina épsilon. Estes achados evidenciam a enterotoxemia como doença de importância para criação de caprinos no Rio Grande do Sul.Five outbreaks of caprine enterotoxaemia in Rio Grande do Sul, Brazil, were studied. The animals were found dead or had a clinical course that usually lasted 2-3 hours. From two farms a clinical manifestation period of 12 hours was reported. Clinical signs were characterized by depression, marked abdominal discomfort, profuse watery diarrhea with fibrin clots, and death. Thirteen necropsies were performed and hydropericardium, hydrothorax and hydroperitoneum were commonly found. The mucosa and serosa of the colon were congested, and its contents was watery with multiple fibrin clots. Serosal hemorrhages and fibrin clots in the gallbladder were also seen. Fibrinous colitis and thyphilitis were the most frequent histological changes. Cerebral microangiopathy was observed in one case, which was

  10. 3D View of Grand Canyon, Arizona

    2000-01-01

    The Grand Canyon is one of North America's most spectacular geologic features. Carved primarily by the Colorado River over the past six million years, the canyon sports vertical drops of 5,000 feet and spans a 445-kilometer-long stretch of Arizona desert. The strata along the steep walls of the canyon form a record of geologic time from the Paleozoic Era (250 million years ago) to the Precambrian (1.7 billion years ago).The above view was acquired by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) instrument aboard the Terra spacecraft. Visible and near infrared data were combined to form an image that simulates the natural colors of water and vegetation. Rock colors, however, are not accurate. The image data were combined with elevation data to produce this perspective view, with no vertical exaggeration, looking from above the South Rim up Bright Angel Canyon towards the North Rim. The light lines on the plateau at lower right are the roads around the Canyon View Information Plaza. The Bright Angel Trail, which reaches the Colorado in 11.3 kilometers, can be seen dropping into the canyon over Plateau Point at bottom center. The blue and black areas on the North Rim indicate a forest fire that was smoldering as the data were acquired on May 12, 2000.Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of International Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products. Dr. Anne Kahle at NASA's Jet Propulsion Laboratory, Pasadena, Calif., is the U.S. Science team leader; Moshe Pniel of JPL is the project manager. ASTER is the only high resolution imaging sensor on Terra. The primary goal of the ASTER mission is to obtain high-resolution image data in 14 channels over the entire land surface, as

  11. Benford's Law for Quality Assurance of Manner of Death Counts in Small and Large Databases.

    Daniels, Jeremy; Caetano, Samantha-Jo; Huyer, Dirk; Stephen, Andrew; Fernandes, John; Lytwyn, Alice; Hoppe, Fred M

    2017-09-01

    To assess if Benford's law, a mathematical law used for quality assurance in accounting, can be applied as a quality assurance measure for the manner of death determination. We examined a regional forensic pathology service's monthly manner of death counts (N = 2352) from 2011 to 2013, and provincial monthly and weekly death counts from 2009 to 2013 (N = 81,831). We tested whether each dataset's leading digit followed Benford's law via the chi-square test. For each database, we assessed whether number 1 was the most common leading digit. The manner of death counts first digit followed Benford's law in all the three datasets. Two of the three datasets had 1 as the most frequent leading digit. The manner of death data in this study showed qualities consistent with Benford's law. The law has potential as a quality assurance metric in the manner of death determination for both small and large databases. © 2017 American Academy of Forensic Sciences.

  12. Perfluoroalkyl substances in waters along the Grand Canal, China.

    Piao, H T; Jiao, X C; Gai, N; Chen, S; Lu, G H; Yin, X C; Yamazaki, E; Yamashita, N; Tan, K Y; Yang, Y L; Pan, J

    2017-07-01

    The Grand Canal, also known as the Beijing-Hangzhou Grand Canal, is a UNESCO World Heritage Site and the longest canal in the world. It is an important trunk line of the South-to-North Water Diversion Project in China. The contamination status and spatial distributions of perfluoroalky substances (PFASs) in waters of the Grand Canal were investigated. The total concentrations of PFASs (∑PFASs) range from 7.8 ng/L to 218.0 ng/L, with high ∑PFASs occurring in the southern part of the Grand Canal which is located in a highly urbanized and economically developed region. The dominance of PFOA showed a decreasing trend toward north while shorter chain homologue proportions increased in the northern part of the Canal which mainly traverses underdeveloped and rural areas in Eastern China. Positive correlations were observed between ∑PFASs and the population density as well as GDP per capita. Intersection with large rivers may affect the contamination levels and composition of PFASs in the water of the Grand Canal near the intersection sites. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Flocculent and grand design spiral galaxies in groups: time scales for the persistence of grand design spiral structures

    Elmegreen, B.G.; Elmegreen, D.M.

    1983-01-01

    Spiral arm classifications were made for 261 low-inclination galaxies in groups listed by Huchra and Geller. The fractional occurrence of grand design spiral structure in nonbarred galaxies was found to increase from approx.0.1 to approx.0.6 and then level off as the group crossing rate or galaxy collision rate in a group increases. A simple model is discussed where the random encounters between galaxies of any type and flocculent galaxies induce transient grand design spirals in the flocculent galaxies. If this grand-design stimulation occurs for binary collisions with impact parameters less than αR 25 , were R 25 is the galactic radius at 25 mag arcsec - 2 , and if the induced grand design spirals persist for an average time equal to #betta# galactic rotations, then the quantity α 2 #betta# equals approximately 3 x 10 4 . If binary collisions are responsible for grand design spirals, then this result implies either that the induced spirals last for many galactic rotations (#betta#>15), or that they can be stimulated by very remote encounters (α>45.) Alternatively, grand design spirals may be stimulated by multiple galaxy encounters, which would be the case for such large α, or by interactions with the potential well of the associated group, rather than by simple binary encounters. Weak correlations between the grand design fraction and the galaxy size, or between this fraction and the total number of galaxies in a group, were also found. Spiral structures of barred galaxies show no correlations with group environment

  14. SO(10) - Grand unification and fermion masses

    Oezer, A.D.

    2005-01-01

    In this work, we study SO(10) grand unification in its full extent by using different explicit matrix representations which exhibit the structure of SO(10) in a very transparent way. Our approach consists mainly of two stages: We derive the explicit expressions of the mass-eigenvalues and mass-eigenstates of the physical gauge bosons from a mass squared-matrix that contains all the information about the mixing parameters among the gauge fields and the phases which are sources for CP violation. In the light of this analysis, we derive the explicit expressions for the interaction Lagrangians of the charged currents, the neutral currents and the charged and colored currents in SO(10). We present explicit expressions of the vector and axial-vector couplings of the two neutral currents in SO(10). We show how the baryon, lepton and baryon minus lepton number violating processes and their explicit CP violating phases are accommodated in the SO(10) theory. The Higgs potential that we use to implement in the Higgs mechanism is constructed in a most general fashion through a careful study of the Higgs fields of SO(10), where we give special emphasis on illustrating the explicit matrix representation of these Higgs fields. The potential part of the Higgs Lagrangian will give us the properties of the minimum of the vacuum, and the kinetic part will give us the mass-squared matrix of the gauge bosons via spontaneous symmetry breakdown. The same Higgs multiplets will be coupled to fermions through a democratic Yukawa matrix. Thereby, we derive explicit expressions for the fermion masses of the third family including Majorana and Dirac masses for neutrinos. We introduce a flavor-eigenbasis for neutrinos and find the mass-eigenstates and mass-eigenvalues of the neutrinos. Explicit expressions for CP violation in the neutrino sector are obtained. In the second stage of our work, we evaluate all the above mentioned quantities. In addition, we present the values of the physical

  15. Biomechanical analysis technique choreographic movements (for example, "grand battman jete"

    Batieieva N.P.

    2015-04-01

    Full Text Available Purpose : biomechanical analysis of the execution of choreographic movement "grand battman jete". Material : the study involved students (n = 7 of the department of classical choreography faculty of choreography. Results : biomechanical analysis of choreographic movement "grand battman jete" (classic exercise, obtained kinematic characteristics (path, velocity, acceleration, force of the center of mass (CM bio parts of the body artist (foot, shin, thigh. Built bio kinematic model (phase. The energy characteristics - mechanical work and kinetic energy units legs when performing choreographic movement "grand battman jete". Conclusions : It was found that the ability of an athlete and coach-choreographer analyze the biomechanics of movement has a positive effect on the improvement of choreographic training of qualified athletes in gymnastics (sport, art, figure skating and dance sports.

  16. Liberating methodological thinking in human sciences from grand theories

    Kharlamov, Nikita; Baldursson, Einar Baldvin

    2016-01-01

    focus on the necessity of a “grand unified theory” at the expense of any and all alternative perspectives. Properties of grand theories are discussed on the examples of Giddens and Bourdieu. It is argued that grand theories hamper a more productive focus on concrete phenomena. Robert Merton’s focus......Many humanistic and social disciplines are naturally inclined to seek for human-, person-, self- centered focus, and develop a holistic theory of such. Such disciplines continually engage with philosophical, metaphysical and meta-theoretical perspectives. This engagement often leads to a singular...... on “middle range” theories is revisited and its continuing relevance is highlighted. The level of abstraction characteristic of such theories, as well as the way they engage with the empirical social reality, are discussed. The article concludes by considering the paradoxical reductionism that can...

  17. Environmental Audit of the Grand Junction Projects Office

    1991-08-01

    The Grand Junction Projects Office (GJPO) is located in Mesa County, Colorado, immediately south and west of the Grand Junction city limits. The US Atomic Energy Commission (AEC) established the Colorado Raw Materials Office at the present-day Grand Junction Projects Office in 1947, to aid in the development of a viable domestic uranium industry. Activities at the site included sampling uranium concentrate; pilot-plant milling research, including testing and processing of uranium ores; and operation of a uranium mill pilot plant from 1954 to 1958. The last shipment of uranium concentrate was sent from GJPO in January, 1975. Since that time the site has been utilized to support various DOE programs, such as the former National Uranium Resource Evaluation (NURE) Program, the Uranium Mill Tailings Remedial Action Project (UMTRAP), the Surplus Facilities Management Program (SFMP), and the Technical Measurements Center (TMC). All known contamination at GJPO is believed to be the result of the past uranium milling, analyses, and storage activities. Hazards associated with the wastes impounded at GJPO include surface and ground-water contamination and potential radon and gamma-radiation exposure. This report documents the results of the Baseline Environmental Audit conducted at Grand Junction Projects Office (GJPO) located in Grand Junction, Colorado. The Grand Junction Baseline Environmental Audit was conducted from May 28 to June 12, 1991, by the Office of Environmental Audit (EH-24). This Audit evaluated environmental programs and activities at GJPO, as well as GJPO activities at the State-Owned Temporary Repository. 4 figs., 12 tabs.

  18. Saturn's Internal Magnetic Field Revealed by Cassini Grand Finale

    Cao, H.; Dougherty, M. K.; Khurana, K. K.; Hunt, G. J.; Provan, G.; Kellock, S.; Burton, M. E.; Burk, T. A.

    2017-12-01

    Saturn's internal magnetic field has been puzzling since the first in-situ measurements during the Pioneer 11 Saturn flyby. Cassini magnetometer measurements prior to the Grand Finale phase established 1) the highly axisymmetric nature of Saturn's internal magnetic field with a dipole tilt smaller than 0.06 degrees, 2) at least an order of magnitude slower secular variation rate compared to that of the current geomagnetic field, and 3) expulsion of magnetic fluxes from the equatorial region towards high latitude. The highly axisymmetric nature of Saturn's intrinsic magnetic field not only challenges dynamo theory but also makes an accurate determination of the interior rotation rate of Saturn extremely difficult. The Cassini spacecraft entered the Grand Finale phase in April 2017, during which time the spacecraft dived through the gap between Saturn's atmosphere and the inner edge of the D-ring 22 times before descending into the deep atmosphere of Saturn. The unprecedented proximity to Saturn (reaching 2500 km above the cloud deck) and the highly inclined nature of the Grand Finale orbits provided an ideal opportunity to decode Saturn's internal magnetic field. The fluxgate magnetometer onboard Cassini made precise vector measurements during the Grand Finale phase. Magnetic signals from the interior of the planet, the magnetospheric ring current, the high-latitude field-aligned current (FAC) modulated by the 10.7 hour planetary period oscillation, and low-latitude FACs were observed during the Grand Finale phase. Here we report the magnetometer measurements during the Cassini Grand Finale phase, new features of Saturn's internal magnetic field revealed by these measurements (e.g., the high degree magnetic moments of Saturn, the level of axisymmetry beyond dipole), and implications for the deep interior of Saturn.

  19. Regional economic impacts of Grand Canyon river runners.

    Hjerpe, Evan E; Kim, Yeon-Su

    2007-10-01

    Economic impact analysis (EIA) of outdoor recreation can provide critical social information concerning the utilization of natural resources. Outdoor recreation and other non-consumptive uses of resources are viewed as environmentally friendly alternatives to extractive-type industries. While outdoor recreation can be an appropriate use of resources, it generates both beneficial and adverse socioeconomic impacts on rural communities. The authors used EIA to assess the regional economic impacts of rafting in Grand Canyon National Park. The Grand Canyon region of northern Arizona represents a rural US economy that is highly dependent upon tourism and recreational expenditures. The purpose of this research is twofold. The first is to ascertain the previously unknown regional economic impacts of Grand Canyon river runners. The second purpose is to examine attributes of these economic impacts in terms of regional multipliers, leakage, and types of employment created. Most of the literature on economic impacts of outdoor recreation has focused strictly on the positive economic impacts, failing to illuminate the coinciding adverse and constraining economic impacts. Examining the attributes of economic impacts can highlight deficiencies and constraints that limit the economic benefits of recreation and tourism. Regional expenditure information was obtained by surveying non-commercial boaters and commercial outfitters. The authors used IMPLAN input-output modeling to assess direct, indirect, and induced effects of Grand Canyon river runners. Multipliers were calculated for output, employment, and income. Over 22,000 people rafted on the Colorado River through Grand Canyon National Park in 2001, resulting in an estimated $21,100,000 of regional expenditures to the greater Grand Canyon economy. However, over 50% of all rafting-related expenditures were not captured by the regional economy and many of the jobs created by the rafting industry are lower-wage and seasonal. Policy

  20. Environmental Audit of the Grand Junction Projects Office

    1991-08-01

    The Grand Junction Projects Office (GJPO) is located in Mesa County, Colorado, immediately south and west of the Grand Junction city limits. The US Atomic Energy Commission (AEC) established the Colorado Raw Materials Office at the present-day Grand Junction Projects Office in 1947, to aid in the development of a viable domestic uranium industry. Activities at the site included sampling uranium concentrate; pilot-plant milling research, including testing and processing of uranium ores; and operation of a uranium mill pilot plant from 1954 to 1958. The last shipment of uranium concentrate was sent from GJPO in January, 1975. Since that time the site has been utilized to support various DOE programs, such as the former National Uranium Resource Evaluation (NURE) Program, the Uranium Mill Tailings Remedial Action Project (UMTRAP), the Surplus Facilities Management Program (SFMP), and the Technical Measurements Center (TMC). All known contamination at GJPO is believed to be the result of the past uranium milling, analyses, and storage activities. Hazards associated with the wastes impounded at GJPO include surface and ground-water contamination and potential radon and gamma-radiation exposure. This report documents the results of the Baseline Environmental Audit conducted at Grand Junction Projects Office (GJPO) located in Grand Junction, Colorado. The Grand Junction Baseline Environmental Audit was conducted from May 28 to June 12, 1991, by the Office of Environmental Audit (EH-24). This Audit evaluated environmental programs and activities at GJPO, as well as GJPO activities at the State-Owned Temporary Repository. 4 figs., 12 tabs

  1. Pequena monografia sobre o Rio Grande do Sul

    Ana Maria Pinho

    2014-05-01

    Full Text Available Pequena monografia desenvolvida por membros do Colégio Sevigne, que versa sobre diversos assuntos a respeito do Rio Grande do Sul, divididos em histórico, fronteiras, organização política administrativa, características geográficas, formação geomorfológica, economia, aspectos históricos e geográficos da capital do Estado, generalidades étnicas, e sobre o gaúcho em si. Grande quantidade de ilustrações e poemas enriquecem o artigo.

  2. Severe accident sequences simulated at the Grand Gulf Nuclear Station

    Carbajo, J.J.

    1999-01-01

    Different severe accident sequences employing the MELCOR code, version 1.8.4 QK, have been simulated at the Grand Gulf Nuclear Station (Grand Gulf). The postulated severe accidents simulated are two low-pressure, short-term, station blackouts; two unmitigated small-break (SB) loss-of-coolant accidents (LOCAs) (SBLOCAs); and one unmitigated large LOCA (LLOCA). The purpose of this study was to calculate best-estimate timings of events and source terms for a wide range of severe accidents and to compare the plant response to these accidents

  3. Grand Minima: Is The Sun Going To Sleep?

    Mcintosh, S. W.; Leamon, R. J.

    2014-12-01

    We explore recent observational work which indicate that the energetics of the sun's outer atmosphere have been on a steady decline for the past decade and perhaps longer. Futher, we show that new investigations into evolution of the Sun's global magnetic activity appear to demonstrate a path through which the Sun can go into, and exit from, a grand activity minimum without great difficulty while retaining an activity cycle - only losing sunspots. Are we at the begining of a new grand(-ish) minimum? Naturally, only time will tell, but the observational evidence hint that one may not be far off to what impact on the Sun-Earth Connection.

  4. Falares: a oralidade como elemento construtor da grande-reportagem

    Alex Criado

    2006-01-01

    Esta tese discute a incorporação da oralidade de falantes excluídos social e culturalmente na grande-reportagem. O foco desta pesquisa é refletir como a grande-reportagem no Brasil, em sua missão de desvendamento do real, tem lidado com a questão da oralidade. Discute os desafios para a incorporação dos registros orais de pessoas com baixa escolaridade, tendo em vista o preconceito que existe na sociedade em relação aos falantes que se utilizam de modalidades diferentes da língua padrão. Prop...

  5. Mitigation measures for the La Grande 1 hydroelectric development

    Faucher, O.; Gagnon, R.

    1992-01-01

    Measures to mitigate environmental impacts of the La Grande 1 hydroelectric development are described. An overview is presented of the La Grande 1 project, its surrounding environment, and the principle environmental repercussions of the reservoir, hydrological changes between the dam and river mouth, construction activities and permanent and temporary structures, and presence of workers. Mitigation measures including compensation, corrective measures (deforestation, selective cutting, fish populations, wildlife populations, land rehabilitation, access roads, fisheries, and erosion control), protective measures, enhancement measures, and contract and employment opportunities for the Cree population are described. 10 refs., 2 figs

  6. Guidebook to Rio Grande rift in New Mexico

    Hawley, J.W.

    1978-01-01

    Discusses the details of geologic features along the rift zone. Included are short papers on topics relative to the overall region. These papers and the road logs are of special interest to any one pursuing further study of the rift. This book is a comprehensive guide to the middle and late Cenozoic geology of the Rio Grande region of Colorado and New Mexico. Though initially used on field trips for the International Symposium on Tectonics and Magmatism of the Rio Grande rift, the guidebook will be useful to anyone interested in the Cenozoic history of the 600-mi-long area extending from central Colorado to El Paso, Texas.

  7. Assessment of Ethical Ideals and Ethical Manners in Care of Older People

    Frilund, Marianne; Fagerström, Lisbeth; Eriksson, Katie; Eklund, Patrik

    2013-01-01

    The aim of this study is to establish structured clusters and well-defined ontological entities (nodes) describing ethical values as both ideal and opportunity for ethical manner as perceived by the caregiver. In this study, we use Bayesian Belief Networks (BBNs) to analyse ethical values (ethos) and ethical manners in daily work with older people. Material is based on questionnaire data collected by the instrument for the self-assessment of individual ethos in the care of older people (ISAEC...

  8. Human, recombinant interleukin-2 induces in vitro histamine release in a dose-dependent manner

    Nielsen, Hans Jørgen; Petersen, L J; Skov, P S

    1995-01-01

    significantly in the supernatant from cells stimulated by rIL-2 in a dose-dependent manner both in patients and volunteers. Total cell-bound histamine was 49.3 +/- 4.1 ng/ml in patients compared to 78.5 +/- 7.7 ng/ml in volunteers (p ... was significantly enhanced in cancer patients compared to volunteers (*p manner in both cancer patients and volunteers. This may in part explain the severe toxicity observed during high...

  9. Pragmatic awareness of Suggestions: From (Im)Polite Mannerism to Attitudinal Appropriateness

    Hamid Allami; Nasim Boustani

    2017-01-01

    The present research seeks to determine: (a) Iranian EFL learners’ application of suggestion semantic formulae ;(b) their attitude of appropriateness in terms of confidence in the employment of appropriate supportive moves; (c), their (im)polite mannerism with respect to the selected strategies; and (d) the relationship between attitude of appropriateness and mannerism of (im)politeness. An Oxford Quick placement Test (OQPT) was administered among 60 Iranian EFL learners to check their langua...

  10. Globalized conflicts, globalized responses. Changing manners of contestation among indigenous communities

    Benyei, Petra; Turreira Garcia, Nerea; Orta-Martínez, Martí

    2017-01-01

    In a globalized world, environmental conflicts affecting indigenous communities (including hunter-gatherer groups) have intensified and grown in their transnational character. These changes have affected the choice of manners of contestation of these groups, favouring in some cases the emergence...... activities and confront conflicts through a truly bottom-up approach. The chapter ends discussing how, despite the potential of such new manners of contestation, the power imbalances that currently underpin many indigenous conflicts are first to be addressed....

  11. A Mission to Reform Manners: Religion, Secularization, and Empire in Early Modern England

    Taback, Naomi Johanna

    2013-01-01

    This dissertation looks at three voluntary societies formed in London shortly after the revolution of 1688. These societies, with overlapping membership, shared a broad vision for the improvement of manners and morals throughout the burgeoning British Empire. The Society for Reformation of Manners, founded in 1691, called for the enforcement of the civil laws against prostitution, swearing, drunkenness, gambling, and other moral crimes. The Society for Promoting Christian Knowledge, founde...

  12. La Grande Guerra fra realtà ed illusione: La Grande Illusion e l’immaginario

    Simone Di Blasi

    2015-12-01

    Full Text Available The aim of this brief essay is to focus on the relation between the meaning of reality and illusion in the movie La Grande Illusion (1937 by Jean Renoir and therefore to find how these ideas of the author may be productive in a thought about the imaginary. After a short look on the movies made at that time on the First World War, there is an overview of the French director poetics, which redefines the conception of the realism, contextualizing its work at the point of convergence of two imaginary “technological lines”, the cinema and the aviation. It follows the analysis of the movie and the illusions, as social largely shared imaginaries, described by the author. In the end it is showed the importance and the of illusion in Renoir’s poetics. Beyond the relationship realityfiction, he thought a dynamic reciprocity among illusion and reality: so that the reality is as “illusion” (a ruled horizon in which it is possible to enjoy a world of play and the illusion as an activity creating contents of “reality”.

  13. Symposium 19: Federal University of Rio Grande do Sul: its Role in the Biochemistry Teaching in the Southernmost Brazilian States

    Clóvis M.D. Wannmacher

    2014-08-01

    think about different teaching strategies and to plan, execute and evaluate a new project of Biochemistry teaching for graduate students. Most of these post graduates are now teaching Biochemistry in several institutions in Rio Grande do Sul and Santa Catarina. However, for many reasons, most of them teach in the traditional manner. Keywords: Teaching strategy, Biochemistry teaching,

  14. Carbonaceous aerosol particles from common vegetation in the Grand Canyon

    Hallock, K.A.; Mazurek, M.A.; Cass, G.R.

    1992-05-01

    The problem of visibility reduction in the Grand Canyon due to fine organic aerosol particles in the atmosphere has become an area of increased environmental concern. Aerosol particles can be derived from many emission sources. In this report, we focus on identifying organic aerosols derived from common vegetation in the Grand Canyon. These aerosols are expected to be significant contributors to the total atmospheric organic aerosol content. Aerosol samples from living vegetation were collected by resuspension of surface wax and resin components liberated from the leaves of vegetation common to areas of the Grand Canyon. The samples were analyzed using high-resolution gas chromatography/mass spectrometry (GC/MS). Probable identification of compounds was made by comparison of sample spectra with National Institute of Standards and Technology (NIST) mass spectral references and positive identification of compounds was made when possible by comparison with authentic standards as well as NIST references. Using these references, we have been able to positively identify the presence of n-alkane and n-alkanoic acid homolog series in the surface waxes of the vegetation sampled. Several monoterpenes, sesquiterpenes, and diterpenes were identified also as possible biogenic aerosols which may contribute to the total organic aerosol abundance leading to visibility reduction in the Grand Canyon

  15. Society and Health in the Lower Rio Grande Valley.

    Madsen, William

    Shedding light on problems of mental health and illness that have baffled public health workers attempting to improve the health and welfare of Mexican Americans living in the lower Rio Grande Valley, this document reports the folk customs, social organization, medical practices, and beliefs of the Mexican American of this area. Chapters describe…

  16. Os grandes consumidores de consultas medicas: um estudo de familia

    M. Pereira Graça

    2002-01-01

    Full Text Available Este artículo describe un estudio sobre algunas características familiares de sujetos grandes consumidores de servicios de salud. Por un lado, se compara un grupo de grandes consumidores de servicios de salud, a nivel de número de consultas, con un grupo control en términos de funcionamiento familiar y actitudes hacia los médicos y la Medicina; por otro lado, se estudia la relación entre la dinámica familiar y las actitudes hacia la Medicina y los médicos en el grupo de los grandes consumidores. Los resultados muestran que los dos grupos de usuarios son significativamente diferentes; además, en el grupo de grandes consumidores el funcionamiento familiar problemático parece ser un factor intermediario en el desarrollo de actitudes menos negativas hacia los médicos y la Medicina. Se discuten las implicaciones que los resultados tienen a nivel de intervención terapéutica.

  17. Workshop and conference on Grand Challenges applications and software technology

    1993-12-31

    On May 4--7, 1993, nine federal agencies sponsored a four-day meeting on Grand Challenge applications and software technology. The objective was to bring High-Performance Computing and Communications (HPCC) Grand Challenge applications research groups supported under the federal HPCC program together with HPCC software technologists to: discuss multidisciplinary computational science research issues and approaches, identify major technology challenges facing users and providers, and refine software technology requirements for Grand Challenge applications research. The first day and a half focused on applications. Presentations were given by speakers from universities, national laboratories, and government agencies actively involved in Grand Challenge research. Five areas of research were covered: environmental and earth sciences; computational physics; computational biology, chemistry, and materials sciences; computational fluid and plasma dynamics; and applications of artificial intelligence. The next day and a half was spent in working groups in which the applications researchers were joined by software technologists. Nine breakout sessions took place: I/0, Data, and File Systems; Parallel Programming Paradigms; Performance Characterization and Evaluation of Massively Parallel Processing Applications; Program Development Tools; Building Multidisciplinary Applications; Algorithm and Libraries I; Algorithms and Libraries II; Graphics and Visualization; and National HPCC Infrastructure.

  18. Eesti nukufilm sai järjekordse grand prix

    2005-01-01

    XII Rahvusvaheline animafilmifestival "KROK-2005", mis toimus laeval, mis sõitis Kiievist Odessasse. Rao Heidmets ja Hardi Volmer said festivali karnevalil oma jänese kostüümi eest grand prix. Eesti filmidest olid programmis "Karl ja Marilyn", "Frank ja Wendy", "Barbarid", "Laud" ja "Conkistadoor"

  19. Piccolo tõi Soomest taas grand prix'

    2009-01-01

    Tänavuse Lappeenrantas toimunud rahvusvahelise suupillifestivali võistumängimisel osalesid suupilliklubi Piccolo orkester, kvartett ja noored solistid. Grand prix' ehk suure võidukarika pälvis Piccolo suupillikvartett koosseisus Ilmar Tõnisson, Andrus Haugas, Andres Kokk ja Elmar Trink. Noorte kategooria võitjaks tunnistati Martin Merevits, kolmandad kohad saavutasid Janek Sildvee bluusi- ja Eduard Einmann diatoonilise suupilli kategoorias

  20. Cosmological origin of the grand-unification mass scale

    Brout, R.; Englert, F.; Spindel, P.

    1979-01-01

    The origin of the universe as a quantum phenomenon leads to a self-consistently generated space-time structure in which the mass of the created particles is O (kappa/sup -1/2/). We interpret the origin of the universe as a phase transition in which the grand unified symmetry is spontaneously broken

  1. Nuove prospettive storiografiche sulla Grande guerra: violenze, traumi, esperienze

    Marco Bizzocchi

    2014-03-01

    Full Text Available Il testo propone, attraverso l’analisi delle recensioni pubblicate sulla rivista internazionale “First World War Studies”, una rassegna su alcuni recenti studi storici sulla Prima guerra mondiale. Dopo la svolta degli anni Settanta-Ottanta, la storiografia sta continuando ad approfondire in particolare il tema dei risvolti sociali e culturali della Grande guerra.

  2. France's grandes écoles accused of elitism

    Hellemans, Alexander

    2010-02-01

    Physicists in France have backed government plans to open up the country's elite grandes écoles to more students from poorer backgrounds. The government wants to allow up to 30% of students to be given free scholarships in an attempt to broaden the social mix of the student body. The physicists say this would not lead to a lowering of standards.

  3. Construction of calibration pads facility, Walker Field, Grand Junction, Colorado

    Ward, D.L.

    1978-08-01

    A gamma-ray spectrometer facility was completed at Walker Field Airport, Grand Junction, Colorado, in November 1976. This report describes spectrometers and their calibration, the construction of the spectrometer facility, the radioelement concentrations, procedures for using the facilites, and environmental considerations

  4. Cyber Resilience in de Bestuurskamer : The Grand Conference in Amsterdam

    Klaver, M.H.A.

    2013-01-01

    Op 16 oktober 2012 vond in Amsterdam The Grand Conference plaats. Deze conferentie werd georganiseerd door het Centre for the Protection of National lnfrastructure (CPNI.NL) in nauwe samenwerking met de Europese Commissie, de Europese Networkand Information Security Agency (ENISA), het Amerikaanse

  5. Winning in straight sets helps in Grand Slam tennis

    Goossens, Dries R.; Kempeneers, Jurgen; Koning, Ruud H.; Spieksma, Frits C. R.

    2015-01-01

    In this contribution, we study whether fatigue resulting from the previous match affects a player's chances of winning his (or her) next match in Grand Slum tennis. We measure relative fatigue levels of two opponents by looking at the difference in number of sets played in their previous match. We

  6. Masses of particles in the SO(18) grand unified model

    Asatryan, G.M.

    1984-01-01

    The grand unified model based on the orthogonal group SO(18) is treated. The model involves four familiar and four mirror families of fermions. Arising of masses of familiar and mirror particles is studied. The mass of the right-handed Wsub(R) boson interacting via right-handed current way is estimated

  7. A grand-canonical ensemble of randomly triangulated surfaces

    Jurkiewicz, J.; Krzywicki, A.; Petersson, B.

    1986-01-01

    An algorithm is presented generating the grand-canonical ensemble of discrete, randomly triangulated Polyakov surfaces. The algorithm is used to calculate the susceptibility exponent, which controls the existence of the continuum limit of the considered model, for the dimensionality of the embedding space ranging from 0 to 20. (orig.)

  8. Flood disaster preparedness: a retrospect from Grand Forks, North Dakota.

    Siders, C; Jacobson, R

    1998-01-01

    Natural disasters often come without warning. The clinical, financial, and business risks can be enormous. Grand Forks' (ND) healthcare systems experienced a flooding disaster of unprecedented proportions in April of 1997. Planned and practiced disaster and evacuation procedures can significantly reduce a healthcare facilities' risk to life, health, and safety. This article retrospectively analyzes disaster preparation and the complete evacuation of the facilities' patients.

  9. Dynkin weights and global supersymmetry in grand unification

    Frampton, P.H.; Kephart, T.W.

    1982-01-01

    The requirement that supersymmetry be unbroken in a supersymmetrized gauge theory is shown to imply vanishing Dynkin weight of the components of the Higgs field representation receiving vacuum expectation values. As a corollary a compact expression is obtained for the Dynkin weights of general SU(N) representations. Examples are given for supersymmetrized grand unified theories

  10. The canonical and grand canonical models for nuclear ...

    Many observables seen in intermediate energy heavy-ion collisions can be explained on the basis of statistical equilibrium. Calculations based on statistical equilibrium can be implemented in microcanonical ensemble, canonical ensemble or grand canonical ensemble. This paper deals with calculations with canonical ...

  11. Interplay between grand unification and supersymmetry in SU(5 ...

    energy MSSM. break the rank, Aulakh and his collaborators [10–12] have showed that R-parity is exact all the way down to low energies. In this case, grand unification tells us something about supersymmetry and even dark matter. In this article ...

  12. Grande Ronde Basin Fish Habitat Enhancement Project : 1998 Annual Report.

    McGowan, Vance R.; Powell, Russ M.

    1999-05-01

    The primary goal of ''The Grande Ronde Basin Fish Habitat Improvement Project'' is to access, create, improve, protect, and restore reparian and instream habitat for anadromous salmonids, thereby maximizing opportunities for natural fish production within the basin.

  13. 163 BONIFACE OKAFOR: THE NIGERIAN SURREALIST PAINTER ...

    Ike Odimegwu

    Surrealism from its Western origin and then take on the art of. Okafor as a veritable ... by the theories of Sigmund Freud who, from his base in. Vienna .... against something else, which is impossible in the case of the universe.” His paintings are ...

  14. Pragmatic awareness of Suggestions: From (ImPolite Mannerism to Attitudinal Appropriateness

    Hamid Allami

    2017-09-01

    Full Text Available The present research seeks to determine: (a Iranian EFL learners’ application of suggestion semantic formulae ;(b their attitude of appropriateness in terms of confidence in the employment of appropriate supportive moves; (c, their (impolite mannerism with respect to the selected strategies; and (d the relationship between attitude of appropriateness and mannerism of (impoliteness. An Oxford Quick placement Test (OQPT was administered among 60 Iranian EFL learners to check their language proficiency level and to satisfy the assumption of homogeneity among the learners. These participants along with 10 American native speakers then underwent a suggestion DCT. The questionnaire included questions addressing interlocutors’ with higher, lower or equal power status and intimate or strange social distance. The DCT also involved attitudinal appropriateness scale and (impoliteness mannerism likert scale to examine the learners’ degree of confidence and mannerism. Besides similarities and differences in the application of suggestion semantic formulae between the Iranian learners and American speakers, the results revealed variations in the two groups’ performances for appropriateness and (impoliteness. The results also indicated a positive relationship between the attitude and mannerism scales.

  15. The Reflection of Javanese Life Manner on the Dongkrek Art and Ritual Performance in Madiun Society

    Sharfina Nur Amalina

    2018-05-01

    Full Text Available This article focuses in the analysis of Javanese life manner within Dongkrek art and ritual performance in Mejayan, Madiun, Indonesia. The purpose of research is to reflect a life manner of Javanese society within a Dongkrek show. The qualitative-descriptive was used as research approach. Data were collected by interview, literature review, and other relevant resources. The results of research show a five points of Javanese manner of life in Dongkrek, represent in the phrase Ambrasta Dur Hangkara, Memayu Hayuning Bawana, Sura Dira Jayaning Lebur Dening Pangastuti, Sadulur Papat Kalima Pancer, and Manunggaling Kawula Gusti. Those phrases contain many moral values that generally can be accepted by society. The phrase represents a human relationship, the manner of life, ways of life, world-view, willingness, and the transcendental relationship between humans and God. It means the purpose of the Javanese manner of life is to reach the perfection of life. The perfection of life is resting on the faith towards to the God through the maturity of spirituality.

  16. Birds of the Reserva Biológica do Mato Grande and surroundings, Rio Grande do Sul, Brazil

    Vizentin-Bugoni, Jeferson; Jacobs, Fernando; Coimbra, Marco Antônio Afonso

    2015-01-01

    The Reserva Biológica do Mato Grande encompasses 5,161 hectares of wetlands, restinga forests and grasslands in southern Brazil. Aiming to assemble a list of bird species occurring in the reserve, we carried out 21 monthly expeditions from July 2007 to March 2009 and an additional visit on October...

  17. Overview of natural gas in Rio Grande do Norte, Brazil; Panorama do gas natural no Rio Grande do Norte

    Teixeira, Pedro Helio Gomes [Universidade Federal do Rio Grande do Norte (GREEN/UFRN), Natal, RN (Brazil). Centro de Tecnologia. Grupo de Estudos Energeticos

    2008-07-01

    This work draws a picture of what the natural gas means to Rio Grande do Norte in its quantitative dimension, expressed in the numbers and reserve indicators, production and structure of consume. In another dimension, it broaches the processes of energetic substitution by the natural gas in the state energetic matrix. (author)

  18. Assessing Grand Strategies: How the EU and NATO Rock the Strategic Boat

    2015-05-01

    part to constitute the embryos of the European Union and NATO grand strategies briefly illustrated in the extracts presented in the epigraph. These... embryos gestated over time becoming de facto grand strategies for these institutions. Applying the characterization of grand strategy elaborated in...6. Michio Kaku, Physics of the Future: How Science Will Shape Human Destiny and Our Daily

  19. Water Environment Evolution along the China Grand Canal

    Mao, F; Wu, Y X; Yang, B F; Li, X J

    2014-01-01

    The China Grand Canal is one of the earliest canals in the world, having lasted for nearly 3000 years. Even its section canals have a rich history, such as the North-South Grand Canal that was established during the Sui Dynasty, whereas the Beijing-Hangzhou Canal was excavated during the Yuan Dynasty and the east line of the South-to-North Water Diversion. As one of the longest in the world, the China Grand Canal's total length is over 3500 kilometers. This length includes the navigable, unnavigable, and underground sections. Making the best use of situations and according to local conditions, the Chinese people harmoniously constructed the Beijing-Hangzhou Canal with nature. Tens of millions of workers took nearly 3000 years to complete the great shipping system. Navigable sections still exist for up to 900 kilometers and the volume of freight traffic is approximately 300 million tons. The canal remains the main logistical channel of the North-to-South Coal Transportation, South-to-North Water Diversion, and resources circulation. To date, China is promoting the success of heritage application. Part of these efforts is the declaration of the China Grand Canal as a World Cultural Heritage by 2014. In addition, the east route of the South-to-North Water Transfer project is planned to be navigable by 2016. The ancient Beijing-Hangzhou Grand Canal will usher in the new ecological civilization and cultural revival along the canal. This paper presents technical methods of water environment evolution research on the river system, river, and water quality along the Beijing-Hangzhou Canal through the integration of historical literature and modern remote sensing image data. The study carried out water environment investigation and analysis along the Beijing-Hangzhou canal by using ETM, SPOT image data, and GPS measurement data. Spatial and temporal evolution characteristics and regulations of the Beijing-Hangzhou Grand Canal regional water environment in the span of

  20. Sebastianus Majewski pittore polacco nell’Abruzzo del XVII secolo e l’altare di San Berardo nella cattedrale di Teramo / Sebastianus Majewski, a polish painter in Abruzzo in the 17th Century and the St. Bernard altar in the cathedral of Teramo

    Clara Iafelice

    2014-06-01

    The artist began his journey in Italy in the first decade of the 17th century. Starting from Cracovia, he made a stop in Vienna, to then continue on towards Venice, Bologna and then, following the Adriatic coast, arrived in Abruzzo, going down to the chietino. It is very likely that the young painter was called to Teramo at the beginning of the 17th century, the anniversary of the death of Saint Berardo. From this moment on, he settled in the city and, in 1628, was united in matrimony with Cesarea Vannemarini, a very prominent family of Teramo. He noted that, five hundred years after the death of the Saint, the painter was commissioned to portray Saint Berardo in the six paintings depicting the Vita e Miracoli del patrono S. Berardo Life and Miracles of the patron Saint Berardo. Along with the coping with the Holy Family, they adorn the altar in fine walnut of the Baroque style leaning against the wall of the sacristy of the cathedral SS. Mary of the Assumption and Berardo of Teramo.

  1. Environmental management at the Grand Rapids Generating Station following the Unit No.1 headcover failure

    Windsor, D.C.

    1993-01-01

    Failure of the headcover of Unit 1 in the Grand Rapids generating station in March, 1992 caused the station to flood, releasing several thousand gallons of oil and removing the station from service for several weeks. Environmental considerations were a considerable part of the station restoration activities, reservoir and flow management programs and responses to public concerns arising from the accident. A major oil spill containment and cleanup program was undertaken, with station cleanup and debris disposal carried out in a manner acceptable to environmental authorities. Reservoir spillage was necessitated by the station shutdown. The spill recreated fish habitat in the spillway and walleye spawning were documented. A compensation program was developed to respond to problems caused by debris flushed from the spillway channel. On spill termination, a fish salvage program removed fish from a scour hole in the spillway channel. A proactive program of public information provided local residents with the facts about the incident and response program, and allayed concerns about public safety. 4 refs., 2 figs

  2. Team science and the physician-scientist in the age of grand health challenges.

    Steer, Clifford J; Jackson, Peter R; Hornbeak, Hortencia; McKay, Catherine K; Sriramarao, P; Murtaugh, Michael P

    2017-09-01

    Despite remarkable advances in medical research, clinicians face daunting challenges from new diseases, variations in patient responses to interventions, and increasing numbers of people with chronic health problems. The gap between biomedical research and unmet clinical needs can be addressed by highly talented interdisciplinary investigators focused on translational bench-to-bedside medicine. The training of talented physician-scientists comfortable with forming and participating in multidisciplinary teams that address complex health problems is a top national priority. Challenges, methods, and experiences associated with physician-scientist training and team building were explored at a workshop held at the Second International Conference on One Medicine One Science (iCOMOS 2016), April 24-27, 2016, in Minneapolis, Minnesota. A broad range of scientists, regulatory authorities, and health care experts determined that critical investments in interdisciplinary training are essential for the future of medicine and healthcare delivery. Physician-scientists trained in a broad, nonlinear, cross-disciplinary manner are and will be essential members of science teams in the new age of grand health challenges and the birth of precision medicine. Team science approaches have accomplished biomedical breakthroughs once considered impossible, and dedicated physician-scientists have been critical to these achievements. Together, they translate into the pillars of academic growth and success. © 2017 New York Academy of Sciences.

  3. Long-term surveillance plan for the Cheney disposal site near Grand Junction, Colorado

    1997-04-01

    This long-term surveillance plan (LTSP) describes the U.S. Department of Energy's (DOE) long-term care program for the Uranium Mill Tailings Remedial Action (UMTRA) Project Cheney disposal site. The site is in Mesa County near Grand Junction, Colorado. The U.S. Nuclear Regulatory Commission (NRC) has developed regulations for the issuance of a general license for the custody and long-term care of UMTRA Project disposal sites in 10 CFR Part 40. The purpose of this general license is to ensure that the UMTRA Project disposal sites are cared for in a manner that protects public health and safety and the environment. Before each disposal site may be licensed, the NRC requires the DOE to submit a site-specific LTSP. The DOE prepared this LTSP to meet this requirement for the Cheney disposal site. The general license becomes effective when the NRC concurs with the DOE's determination that remedial action is complete and the NRC formally accepts this plan. This document describes the long-term surveillance program the DOE will implement to ensure that the Cheney disposal site performs as designed. The program is based on site inspections to identify potential threats to disposal cell integrity. The LTSP is based on the UMTRA Project long-term surveillance program guidance and meets the requirements of 10 CFR section 40.27(b) and 40 CFR section 192.03

  4. Mind your "smoking manners": the tobacco industry tactics to normalize smoking in Japan.

    Kashiwabara, Mina; Armada, Francisco

    2013-11-09

    The tobacco industry has adapted its promotional strategies as tobacco-control measures have increased. This paper describes the tobacco industry's strategies on smoking manners and illustrates how these interfere with tobacco-control policy in Japan where tobacco control remains weak. Information on the tobacco industry's promotional strategies in Japan was collected through direct observation, a review of tobacco industry documents and a literature review. The limitation of the study would be a lack of industry documents from Japan as we relied on a database of a U.S. institution to collect internal documents from the tobacco industry. Japan Tobacco began using the manners strategies in the early 1960s. Collaborating with wide range of actors -including local governments and companies- the tobacco industry has promoted smoking manners to wider audiences through its advertising and corporate social responsibility activities. The tobacco industry in Japan has taken advantage of the cultural value placed on manners in Japan to increase the social acceptability of smoking, eventually aiming to diminish public support for smoke-free policies that threatens the industry's business. A stronger enforcement of the WHO Framework Convention on Tobacco Control is critical to counteracting such strategies.

  5. 26 CFR 1.881-1 - Manner of taxing foreign corporations.

    2010-04-01

    ... tax avoidance purposes, whether or not such corporation is engaged in trade or business in the United... TAX (CONTINUED) INCOME TAXES Foreign Corporations § 1.881-1 Manner of taxing foreign corporations. (a) Classes of foreign corporations. For purposes of the income tax, foreign corporations are divided into two...

  6. 17 CFR 17.02 - Form, manner and time of filing reports.

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Form, manner and time of filing reports. 17.02 Section 17.02 Commodity and Securities Exchanges COMMODITY FUTURES TRADING... markets located in that time zone, and central time for information concerning all other markets. (b...

  7. Organizing artistic activities in a recurrent manner : (on the nature of) entrepreneurship in the performing arts

    Bergamini, Michela; Van de Velde, Ward; Van Looy, Bart; Visscher, Klaasjan

    2017-01-01

    A majority of performing arts organizations active in classical music, theatre, and contemporary dance rely on funding from "third parties" in order to organize productions in a recurrent manner. We adopt an entrepreneurial perspective to inform the debate on the economic sustainability of

  8. Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner

    Kny, Melanie; Standera, Sybille; Hartmann-Petersen, Rasmus

    2011-01-01

    in ER-associated protein degradation (ERAD) and interacts directly with the ubiquitin ligase Hrd1, which is found in high molecular mass complexes of the ER membrane. Here we present the first evidence that Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like (UBL) domain-dependent manner. We...

  9. Impact of Video Feedback on Teachers' Eye-Contact Mannerisms in Microteaching.

    Karasar, Niyazi

    To test the impact of video feedback on teachers' eye-contact mannerisms in microteaching in inservice vocational teacher education, the study utilized video recordings from the data bank generated by previous studies conducted at the Ohio State University's Center for Vocational and Technical Education. The tapes were assigned through a…

  10. Nucleoside analogues are activated by bacterial deoxyribonucleoside kinases in a species-specific manner

    Sandrini, Michael; Clausen, Anders; On, Stephen L. W.

    2007-01-01

    To investigate the bactericidal activity of antiviral and anticancer nucleoside analogues against a variety of pathogenic bacteria and characterize the activating enzymes, deoxyribonucleoside kinases (dNKs). Several FDA-approved nucleoside analogue drugs were screened for their potential bacteric......-specific manner. Therefore, nucleoside analogues have a potential to be employed as antibiotics in the fight against emerging multiresistant bacteria....

  11. Rheological properties of a nematic cell oriented in a planar manner

    Barbero, G.; Meyer, C.; Lelidis, I.

    2010-01-01

    We propose a simple model to investigate the rheological properties of a nematic cell oriented in a planar manner. The storage and loss modulus are evaluated in the case of strong and weak anchoring conditions. The contribution of the surface viscosity to the rheological parameters is also considered.

  12. Astrocytic connexin hemichannels are regulated by PKC phosphorylation in an isoform-specific manner

    MacAulay, N.; Alstrom, J. S.; Hansen, D. B.

    2017-01-01

    /activation of PKC and by mutational disruption of the proposed PKC-phosphorylation sites. Cx30 hemichannel activity, in contrast, was down-regulated by PKC activation, in a manner suggesting PKC-mediated channel closure. No single PKC consensus site could be assigned to this regulatory property by mutational...

  13. Weighting of Acoustic Cues to a Manner Distinction by Children with and without Hearing Loss

    Nittrouer, Susan; Lowenstein, Joanna H.

    2015-01-01

    Purpose: Children must develop optimal perceptual weighting strategies for processing speech in their first language. Hearing loss can interfere with that development, especially if cochlear implants are required. The three goals of this study were to measure, for children with and without hearing loss: (a) cue weighting for a manner distinction,…

  14. Silence and table manners : When environments activate norms (Retracted article. See vol. 38, pg. 1378, 2012)

    Joly, Janneke F.; Stapel, Diederik A.; Lindenberg, Siegwart M.

    Two studies tested the conditions under which an environment (e. g., library, restaurant) raises the relevance of environment-specific social norms (e. g., being quiet, using table manners). As hypothesized, the relevance of such norms is raised when environments are goal relevant ("I am going there

  15. 40 CFR 141.203 - Tier 2 Public Notice-Form, manner, and frequency of notice.

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Tier 2 Public Notice-Form, manner, and frequency of notice. 141.203 Section 141.203 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...., house renters, apartment dwellers, university students, nursing home patients, prison inmates, etc...

  16. 40 CFR 141.204 - Tier 3 Public Notice-Form, manner, and frequency of notice.

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Tier 3 Public Notice-Form, manner, and frequency of notice. 141.204 Section 141.204 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...., house renters, apartment dwellers, university students, nursing home patients, prison inmates, etc...

  17. Clinical Immersion and Biomedical Engineering Design Education: "Engineering Grand Rounds".

    Walker, Matthew; Churchwell, André L

    2016-03-01

    Grand Rounds is a ritual of medical education and inpatient care comprised of presenting the medical problems and treatment of a patient to an audience of physicians, residents, and medical students. Traditionally, the patient would be in attendance for the presentation and would answer questions. Grand Rounds has evolved considerably over the years with most sessions being didactic-rarely having a patient present (although, in some instances, an actor will portray the patient). Other members of the team, such as nurses, nurse practitioners, and biomedical engineers, are not traditionally involved in the formal teaching process. In this study we examine the rapid ideation in a clinical setting to forge a system of cross talk between engineers and physicians as a steady state at the praxis of ideation and implementation.

  18. A Grande Reportagem em Televisão

    Teixeira, Clara Manuela Araújo

    2009-01-01

    Monografia apresentada à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Licenciada em Ciências da Comunicação Este projecto de graduação é dedicado ao estudo da elaboração de uma grande reportagem em televisão. As próximas páginas procuram dar a conhecer ao leitor as diferentes fases do processo de realização de uma grande reportagem audiovisual: desde a preparação à investigação feita pelo jornalista, passando pela recolha de informação no terr...

  19. DOE-Grand Junction logging model data synopsis

    Mathews, M.A.; Koizumi, C.J.; Evans, H.B.

    1978-05-01

    This synopsis provides the available data concerning the logging models at the DoE-Grand Junction facility, to date (1976). Because gamma-ray logs are used in uranium exploration to estimate the grade (percent U 3 O 8 ) and the thickness of uranium ore zones in exploration drill holes, logging models are required to calibrate the gamma-ray logging equipment in order to obtain accuracy, uniformity, standardization, and repeatability during logging. This quality control is essential for accurate ore reserve calculations and for estimates of ore potential. The logging models at the DoE-Grand Junction facility are available for use by private industry in calibrating their gamma-ray logging equipment. 21 figures, 26 tables

  20. Grand societal challenges in information systems research and education

    vom Brocke, Jan; Hofmann, Sara; Tumbas, Sanja

    2015-01-01

    This book examines how information systems research and education can play a major role in contributing to solutions to the Societal Grand Challenges formulated in "The Millennium Project" (millenium-project.org). Individual chapters focus on specific challenges, review existing approaches and contributions towards solutions in information systems research and outline a research agenda for these challenges. The topics considered in this volume range from climate change, population growth, global ICT availability, breakthroughs in science and technology and energy demand to ethical decision-making, policymaking, gender status and transnational crime prevention. It is the first book to present ideas on how the Information Systems discipline can contribute to the solution on this wide spectrum of grand societal challenges.

  1. Standardized methods for Grand Canyon fisheries research 2015

    Persons, William R.; Ward, David L.; Avery, Luke A.

    2013-01-01

    This document presents protocols and guidelines to persons sampling fishes in the Grand Canyon, to help ensure consistency in fish handling, fish tagging, and data collection among different projects and organizations. Most such research and monitoring projects are conducted under the general umbrella of the Glen Canyon Dam Adaptive Management Program and include studies by the U.S. Geological Survey (USGS), U.S. Fish and Wildlife Service (FWS), National Park Service (NPS), the Arizona Game and Fish Department (AGFD), various universities, and private contractors. This document is intended to provide guidance to fieldworkers regarding protocols that may vary from year to year depending on specific projects and objectives. We also provide herein documentation of standard methods used in the Grand Canyon that can be cited in scientific publications, as well as a summary of changes in protocols since the document was first created in 2002.

  2. US DOE Grand Challenge in Computational Accelerator Physics

    Ryne, R.; Habib, S.; Qiang, J.; Ko, K.; Li, Z.; McCandless, B.; Mi, W.; Ng, C.; Saparov, M.; Srinivas, V.; Sun, Y.; Zhan, X.; Decyk, V.; Golub, G.

    1998-01-01

    Particle accelerators are playing an increasingly important role in basic and applied science, and are enabling new accelerator-driven technologies. But the design of next-generation accelerators, such as linear colliders and high intensity linacs, will require a major advance in numerical modeling capability due to extremely stringent beam control and beam loss requirements, and the presence of highly complex three-dimensional accelerator components. To address this situation, the U.S. Department of Energy has approved a ''Grand Challenge'' in Computational Accelerator Physics, whose primary goal is to develop a parallel modeling capability that will enable high performance, large scale simulations for the design, optimization, and numerical validation of next-generation accelerators. In this paper we report on the status of the Grand Challenge

  3. Low-energy neutral current phenomenology and grand unified theories

    Del Aguila, F.; Mendez, A.

    1981-01-01

    We derive necessary and sufficient conditions to be satisfied by any expanded electroweak gauge model in order to reproduce the standard model low-energy neutral current predictions. These conditions imply several constraints on the neutral gauge boson masses and the quantum number assignments for the ordinary fermions. Using these conditions, we prove that the popular grand unified theories based on the gauge groups SO(10) and E6 can only accommodate trivial extensions of the standard model. As a consequence, if any of these grand unified models works at some energy scale, present low-energy neutral current phenomenology implies that the Z-boson must be produced with the expected mass and couplings to the ordinary fermions. Any additional neutral gauge boson (with the possible exception of very heavy ones) could only be produced in hadronic collisions and it would not decay in e + e - . (orig.)

  4. GrandBase: generating actionable knowledge from Big Data

    Xiu Susie Fang

    2017-08-01

    Full Text Available Purpose – This paper aims to propose a system for generating actionable knowledge from Big Data and use this system to construct a comprehensive knowledge base (KB, called GrandBase. Design/methodology/approach – In particular, this study extracts new predicates from four types of data sources, namely, Web texts, Document Object Model (DOM trees, existing KBs and query stream to augment the ontology of the existing KB (i.e. Freebase. In addition, a graph-based approach to conduct better truth discovery for multi-valued predicates is also proposed. Findings – Empirical studies demonstrate the effectiveness of the approaches presented in this study and the potential of GrandBase. The future research directions regarding GrandBase construction and extension has also been discussed. Originality/value – To revolutionize our modern society by using the wisdom of Big Data, considerable KBs have been constructed to feed the massive knowledge-driven applications with Resource Description Framework triples. The important challenges for KB construction include extracting information from large-scale, possibly conflicting and different-structured data sources (i.e. the knowledge extraction problem and reconciling the conflicts that reside in the sources (i.e. the truth discovery problem. Tremendous research efforts have been contributed on both problems. However, the existing KBs are far from being comprehensive and accurate: first, existing knowledge extraction systems retrieve data from limited types of Web sources; second, existing truth discovery approaches commonly assume each predicate has only one true value. In this paper, the focus is on the problem of generating actionable knowledge from Big Data. A system is proposed, which consists of two phases, namely, knowledge extraction and truth discovery, to construct a broader KB, called GrandBase.

  5. Grand challenges for integrated USGS science—A workshop report

    Jenni, Karen E.; Goldhaber, Martin B.; Betancourt, Julio L.; Baron, Jill S.; Bristol, R. Sky; Cantrill, Mary; Exter, Paul E.; Focazio, Michael J.; Haines, John W.; Hay, Lauren E.; Hsu, Leslie; Labson, Victor F.; Lafferty, Kevin D.; Ludwig, Kristin A.; Milly, Paul C. D.; Morelli, Toni L.; Morman, Suzette A.; Nassar, Nedal T.; Newman, Timothy R.; Ostroff, Andrea C.; Read, Jordan S.; Reed, Sasha C.; Shapiro, Carl D.; Smith, Richard A.; Sanford, Ward E.; Sohl, Terry L.; Stets, Edward G.; Terando, Adam J.; Tillitt, Donald E.; Tischler, Michael A.; Toccalino, Patricia L.; Wald, David J.; Waldrop, Mark P.; Wein, Anne; Weltzin, Jake F.; Zimmerman, Christian E.

    2017-06-30

    Executive SummaryThe U.S. Geological Survey (USGS) has a long history of advancing the traditional Earth science disciplines and identifying opportunities to integrate USGS science across disciplines to address complex societal problems. The USGS science strategy for 2007–2017 laid out key challenges in disciplinary and interdisciplinary arenas, culminating in a call for increased focus on a number of crosscutting science directions. Ten years on, to further the goal of integrated science and at the request of the Executive Leadership Team (ELT), a workshop with three dozen invited scientists spanning different disciplines and career stages in the Bureau convened on February 7–10, 2017, at the USGS John Wesley Powell Center for Analysis and Synthesis in Fort Collins, Colorado.The workshop focused on identifying “grand challenges” for integrated USGS science. Individual participants identified nearly 70 potential grand challenges before the workshop and through workshop discussions. After discussion, four overarching grand challenges emerged:Natural resource security,Societal risk from existing and emerging threats,Smart infrastructure development, andAnticipatory science for changing landscapes.Participants also identified a “comprehensive science challenge” that highlights the development of integrative science, data, models, and tools—all interacting in a modular framework—that can be used to address these and other future grand challenges:Earth Monitoring, Analyses, and Projections (EarthMAP)EarthMAP is our long-term vision for an integrated scientific framework that spans traditional scientific boundaries and disciplines, and integrates the full portfolio of USGS science: research, monitoring, assessment, analysis, and information delivery.The Department of Interior, and the Nation in general, have a vast array of information needs. The USGS meets these needs by having a broadly trained and agile scientific workforce. Encouraging and supporting

  6. Bias Gender Dalam Novel La Grande Borne Karya NH. Dini

    Dilla, Raili Irfa; Thahar, Harris Effendi; Zulfikarni, Zulfikarni

    2013-01-01

    The purpose of this article was to describe the gender diffraction in novel La Grande Borne by Nh. Dini, evaluated from five aspects, (a) marginalization, (b) subordination, (c) stereotype, (d) violence, and (e) double work load. The data of this study was the sentences that refer to the gender diffraction.. The analyze technics were (1) describe the data, (2) analyze the data that refer to gender, (3) lnterpretated the unfair in gender, and (4) conclusion. The results of this study could be ...

  7. L'espace mondial des grandes manifestations sportives internationales

    Daniel MATHIEU

    1989-06-01

    Full Text Available La carte des grandes manifestations sportives mondiales montre une forte concentration des épreuves dans un petit nombre de pays développés, en particulier l'Europe occidentale. L'examen des nations concernées par les tournois majeurs du tennis et par le cyclisme professionnel soulignent, avec les nuances propres à chacun des sports, l'étroitesse des espaces intéressés.

  8. Magnetostratigraphy of the Grande Ronde Basalt Pasco Basin, Washington

    Packer, D.R.; Petty, M.H.

    1979-01-01

    The paleomagnetic measurements of samples from the holes sampled have shown that there are four magnetic correlation lines, between adjacent flows in holes that have distinctly different mean stratigraphic inclinations, and two magnetic polarity boundaries that can be used for magnetic correlation in the Grande Ronde Basalt in the Pasco Basin. The results of paleomagnetic measurements of samples from the Wanapum Basalt and Saddle Mountains Basalt indicate that the potential for magnetostratigraphic correlation in these sequences is also good

  9. Bitcoin Market Volatility Analysis Using Grand Canonical Minority Game

    Matteo Ortisi

    2016-12-01

    Full Text Available In this paper we propose to use the Grand Canonical Minority Game (GCMG, a highly simplified financial market model as a model of bitcoin market to show how the lack of an income for “miners”, similar to yield earned by bond holders, could be a structural reason for high volatility of bitcoin price in a reference currency. Coherently with present analysis, the introduction of future contracts on bitcoin would have the effect of reducing the overall market volatility.

  10. Differential compaction mechanism for earth fissures near Casa Grande, Arizona.

    Jachens, R.C.; Holzer, T.L.

    1982-01-01

    Precise gravity measurements indicate that earth fissures or tension cracks caused by ground-water withdrawal within a 10km2 area SE of Casa Grande are associated with relief on the buried interface between the alluvial aquifer and underlying bedrock. These relations suggest that the fissures are forming in response to localized differential compaction caused by localized variations of aquifer-system thickness. -from Authors

  11. Proceedings of the fourth workshop on grand unification

    Weldon, H.A.; Langacker, P.; Steinhardt, P.J.

    1983-01-01

    This book compiles the papers presented at the fourth conference of grand unified theories of nuclear physics held in University of Pennsylvania April 1983. The topics covered were proton decay theory; angular distribution and flux of atmospheric neutrinos; atmospheric neutrinos and astrophysical neutrinos in proton decay experiments; review of future nucleon decay experiments; monopole experiments; searches for magnetic monopole; monopoles, gauge, fields and anomalies; darkmatter, galaxies and voids; adiabatic fluctuations; supersymmetry, supergravity, and Kaluza-Klein theories; superstring theory and superunification.

  12. Radiative breaking of cosmologically acceptable grand unified theories

    Gato, B.; Leon, J.; Quiros, M.

    1984-01-01

    We present a cosmologically acceptable grand unified model where the breaking of SU(5) proceeds through radiative corrections induced by supergravity soft-breaking terms. The breaking scale is determined by dimensional transmutation. The model is compatible with the radiative breaking of SU(2)sub(L)xU(1)sub(Y) which provides an experimentally accessible low energy particle spectrum and small top quark mass. (orig.)

  13. Z2 vortex strings in grand unified theories

    Olive, D.; Turok, N.

    1982-01-01

    Spontaneously broken gauge theories may display distinct vortex string solutions for the disconnected components of the exact gauge symmetry group. A type of Higgs mechanism thought to apply in grand unified theories as being responsible for fermion masses yields Z 2 vortex lines, irrespectively of the group. These could seed galaxy formation if the corresponding fermion masses are superheavy. More generally a Higgs mechanism producing Zsub(n) vortex strings is presented. (orig.)

  14. Grande Ronde Basin Supplementation Program; Lostine River, 2000 Annual Report.

    Onjukka, Sam T. (Oregon Department of Fish and Wildlife, Portland, OR); Harbeck, Jim (Nez Perce Tribe, Department of Fisheries Resource Management, Enterprise, OR)

    2003-03-01

    The Northwest Power Planning Council (NPPC) identified supplementation as a high priority to achieve its goal of increasing runs of anadromous fish in the Columbia Basin. Supplementation activities in the Lostine River and associated monitoring and evaluation conducted by the Nez Perce Tribe relate directly to the needs addressed in the Columbia River Basin Fish and Wildlife Program (NPPC 1994). Measure 7.4L.1 of the Program mandates that appropriate research accompany any proposed supplementation. In addition, measure 7.3B.2 of the Program stresses the need for evaluating supplementation projects to assess their ability to increase production. Finally, Section 7.4D.3 encourages the study of hatchery rearing and release strategies to improve survival and adaptation of cultured fish. In 1997, Oregon Department of Fisheries and Wildlife (ODFW) requested a modification of Permit 1011 to allow the take of adult spring chinook salmon. In 1998, the Nez Perce Tribe also requested a permit specific to activities on Lostine River. The permit was issued in 2000. A special condition in the permits required the development of a long term management plan for the spring chinook salmon of the Grande Ronde Basin. The Nez Perce Tribe, ODFW, and the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) completed a formal long range plan entitled ''Grande Ronde Basin Endemic Spring Chinook Salmon Supplementation Program''. The program proposes to increase the survival of spring chinook salmon in the Grand Ronde Basin through hatchery intervention. Adult salmon from the Lostine River, Catherine Creek, and the Upper Grande Ronde River are used for a conventional supplementation program in the basin. The Nez Perce program currently operates under the ESA Section 10 Permit 1149.

  15. Grande Ronde Basin Supplementation Program; Lostine River, 2001 Annual Report.

    Onjukka, Sam T. (Oregon Department of Fish and Wildlife, Portland, OR); Harbeck, Jim (Nez Perce Tribe, Department of Fisheries Resource Management, Enterprise, OR)

    2003-03-01

    The Northwest Power Planning Council (NPPC) identified supplementation as a high priority to achieve its goal of increasing runs of anadromous fish in the Columbia Basin. Supplementation activities in the Lostine River and associated monitoring and evaluation conducted by the Nez Perce Tribe relate directly to the needs addressed in the Columbia River Basin Fish and Wildlife Program (NPPC 1994). Measure 7.4L.1 of the Program mandates that appropriate research accompany any proposed supplementation. In addition, measure 7.3B.2 of the Program stresses the need for evaluating supplementation projects to assess their ability to increase production. Finally, Section 7.4D.3 encourages the study of hatchery rearing and release strategies to improve survival and adaptation of cultured fish. In 1997, Oregon Department of Fisheries and Wildlife (ODFW) requested a modification of Permit 1011 to allow the take of adult spring chinook salmon. In 1998, the Nez Perce Tribe also requested a permit specific to activities on Lostine River. The permit was issued in 2000. A special condition in the permits required the development of a long term management plan for the spring chinook salmon of the Grande Ronde Basin. The Nez Perce Tribe, ODFW, and the Confederated Tribes of the Umatilla Indian Reservation (CTUIR) completed a formal long range plan entitled ''Grande Ronde Basin Endemic Spring Chinook Salmon Supplementation Program''. The program proposes to increase the survival of spring chinook salmon in the Grand Ronde Basin through hatchery intervention. Adult salmon from the Lostine River, Catherine Creek, and the Upper Grande Ronde River are used for a conventional supplementation program in the basin. The Nez Perce program currently operates under the ESA Section 10 Permit 1149.

  16. Non-natural manners of death among users of illicit drugs: Substance findings.

    Delaveris, Gerd Jorunn M; Teige, Brita; Rogde, Sidsel

    2014-05-01

    The aim of the study was to explore differences and similarities between the various non-natural manners of death (accident, suicide, homicide) regarding toxicological findings in illicit drug users. Medicolegal autopsy reports from the Institute of Forensic Medicine University of Oslo concerning deaths from 2000 to 2009 were investigated. Those aged 20-59 whose manner of death was non-natural and who tested positive for any narcotic drug (morphine/heroin, amphetamines, ecstasy, cannabis, LSD, PCP, and high levels of GHB in addition to methadone and buprenorphine) were selected. All substance findings were registered and categorized (narcotics, ethanol, and medicinal products). Of the 1603 autopsies that met the selection criteria, 1204 were accidental intoxications, 122 accidents other than intoxication, 114 suicides by intoxication, 119 non-intoxication suicides, and 44 victims of homicide. Poly drug use was found in all manners of death. The drug profile as well as the mean number of substances (illicit drugs and medicinal products) varied from 2.9 to 4.6 substances per case, depending on the manner of death. Intoxication suicides had the highest number of substances and a total drug profile similar to accidental intoxications. Non-intoxication suicides had a total drug profile similar to homicide and accidents other than intoxication. The number of substances found per case increased during the decade, mainly due to increased findings of methadone, cannabis, amphetamines, and benzodiazepines. Methadone findings increased much more than buprenorphine. Methadone was found 20 times more often than buprenorphine in accidental intoxication cases. In summary, poly drug findings are common in adults who suffer a non-natural death while using illicit drugs. The different manners of death have some specific characteristics and significant differences regarding drug profile. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  17. Deciphering solar magnetic activity: on grand minima in solar activity

    McIntosh, Scott W. [High Altitude Observatory, National Center for Atmospheric Research, Boulder, CO (United States); Leamon, Robert J., E-mail: mscott@ucar.edu [Department of Physics, Montana State University, Bozeman, MT (United States)

    2015-07-08

    The Sun provides the energy necessary to sustain our existence. While the Sun provides for us, it is also capable of taking away. The weather and climatic scales of solar evolution and the Sun-Earth connection are not well- understood. There has been tremendous progress in the century since the discovery of solar magnetism—magnetism that ultimately drives the electromagnetic, particulate, and eruptive forcing of our planetary system. There is contemporary evidence of a decrease in solar magnetism, perhaps even indicators of a significant downward trend, over recent decades. Are we entering a minimum in solar activity that is deeper and longer than a typical solar minimum, a “grand minimum”? How could we tell if we are? What is a grand minimum and how does the Sun recover? These are very pertinent questions for modern civilization. In this paper we present a hypothetical demonstration of entry and exit from grand minimum conditions based on a recent analysis of solar features over the past 20 years and their possible connection to the origins of the 11(&ish) year solar activity cycle.

  18. United States Department of Energy, Grand Junction Office

    1980-01-01

    The Grand Junction Office (GJO), US Department of Energy (DOE), develops and administers programs for evaluating domestic uranium resources and the production capability of industry; for developing resource planning information for DOE; and for advancing geologic and geophysical exploration concepts and techniques. In addition, GJO administers the leasing of mineral lands under DOE control, and carries out activities relating to the environmental aspects of uranium mining and milling, including remedial programs. The Office is staffed by administrative and technical program-management personnel. Bendix Field Engineering Corporation (Bendix) is the DOE operating contractor at the Grand Junction, Colorado, Government-owned/contractor-operated (GOCO) facility. The technical staffs of both GJO and Bendix are primarily geoscience-oriented. Specifically during 1980, uranium resource assessment on 135 National Topographic Map Series (NTMS) quadrangles was completed, along with other specific studies, to yield October 1980 national resource estimates. In addition, updated uranium supply analysis and production capability projections were completed. Another key aspect of this successful program was the development of improved geophysical and geochemical equipment and techniques in support of uranium resource assessment. Much of the hardware and know-how developed was turned over to the public and to the uranium industry at large for application to uranium exploration and the assessment of uranium company resources. The Grand Junction Office also participated actively during 1980 in international cooperative research on uranium exploration techniques and on the geology of uranium deposits

  19. Light grand unified theory triplets and Yukawa splitting

    Rakshit, Subhendu; Shadmi, Yael; Raz, Guy; Roy, Sourov

    2004-01-01

    Triplet-mediated proton decay in grand unified theories (GUTs) is usually suppressed by arranging a large triplet mass. Here we explore instead a mechanism for suppressing the couplings of the triplets to the first and second generations compared to the Yukawa couplings, so that the triplets can be light. This mechanism is based on a 'triplet symmetry' in the context of product-group GUTs. We study two possibilities. The first possibility, which requires the top Yukawa coupling to arise from a nonrenormalizable operator at the GUT scale, is that all triplet couplings to matter are negligible, so that the triplets can be at the weak scale, giving new evidence for grand unification. The second possibility is that some triplet couplings, and in particular Ttb and Tt-barl-bar, are equal to the corresponding Yukawa couplings. This would give a distinct signature of grand unification if the triplets were sufficiently light. However, we derive a model-independent bound on the triplet mass in this case, which is at least 10 6 GeV. Finally, we construct an explicit viable GUT model based on Yukawa splitting, with the triplets at 10 14 GeV, as required for coupling unification to work. This model requires no additional thresholds below the GUT scale

  20. Deciphering Solar Magnetic Activity: On Grand Minima in Solar Activity

    Scott William Mcintosh

    2015-07-01

    Full Text Available The Sun provides the energy necessary to sustain our existence. While the Sun provides for us, it is also capable of taking away. The weather and climatic scales of solar evolution and the Sun-Earth connection are not well understood. There has been tremendous progress in the century since the discovery of solar magnetism - magnetism that ultimately drives the electromagnetic, particulate and eruptive forcing of our planetary system. There is contemporary evidence of a decrease in solar magnetism, perhaps even indicators of a significant downward trend, over recent decades. Are we entering a minimum in solar activity that is deeper and longer than a typical solar minimum, a grand minimum? How could we tell if we are? What is a grand minimum and how does the Sun recover? These are very pertinent questions for modern civilization. In this paper we present a hypothetical demonstration of entry and exit from grand minimum conditions based on a recent analysis of solar features over the past 20 years and their possible connection to the origins of the 11(-ish year solar activity cycle.

  1. Deciphering Solar Magnetic Activity: On Grand Minima in Solar Activity

    Mcintosh, Scott; Leamon, Robert

    2015-07-01

    The Sun provides the energy necessary to sustain our existence. While the Sun provides for us, it is also capable of taking away. The weather and climatic scales of solar evolution and the Sun-Earth connection are not well understood. There has been tremendous progress in the century since the discovery of solar magnetism - magnetism that ultimately drives the electromagnetic, particulate and eruptive forcing of our planetary system. There is contemporary evidence of a decrease in solar magnetism, perhaps even indicators of a significant downward trend, over recent decades. Are we entering a minimum in solar activity that is deeper and longer than a typical solar minimum, a "grand minimum"? How could we tell if we are? What is a grand minimum and how does the Sun recover? These are very pertinent questions for modern civilization. In this paper we present a hypothetical demonstration of entry and exit from grand minimum conditions based on a recent analysis of solar features over the past 20 years and their possible connection to the origins of the 11(-ish) year solar activity cycle.

  2. Blaise Cendrars et ses 'Grands Fétiches'

    Doubinsky, Sebastien

    2016-01-01

    Quand l’écrivain Blaise Cendrars fait paraître sa série de poèmes réunis sous le titre Les Grands Fétiches dans la revue bruxelloise Le Disque vert en 1922, il semble participer de la grande mode « Nègre » qui secoue la France en cette période. Co-découvreur des arts dits « primitives » dès 1916...... avec Guillaume Apollinaire, l’écrivain va les insérer dans son travail poétique comme miroirs inversés de la modernité occidentale. Cependant, même s'il utilise certains des clichés racistes de son époque, il se place lui-même dans le camp des « mélanophiles », et va se servir de cet Art Nègre pour...... repousser à l'extrême les frontières de la modernité. La série des Grands Fétiches participe directement de ce désir, et nous tenterons de montrer dans cet article comment ces objets dits primitifs deviennent des objets « instables » qui remettent en question la définition même du poétique....

  3. Lower Grande Ronde smolt trap monitoring. Annual report 1996

    Setter, A.; Carmichael, R.W.

    1998-01-01

    The authors sampled downstream migrating salmonids at Boggan's Oasis in the Grande Ronde River with a screw trap during 1995 and a scoop trap during 1996. Sampling began in March and terminated early in June. Wild spring chinook and wild/hatchery steelhead were collected and marked to assess migration patterns and timing. Fish were marked with tags in order to obtain downstream migration data with minimal fish handling. Observations were recorded when a fish swam through an interrogation monitor at hydroelectric facilities downstream. The second year for monitoring smolts leaving the Grande Ronde River was completed in 1995. The authors continued to pursue moving to a permanent location downstream for 1997 because of the limitations for trapping smolts at Boggan's Oasis. This involved reconnaissance surveys of several potential sites near the mouth of the river from 1994--1996. During February of 1996, a water velocity and bottom topography assessment was completed. Results of the assessment were used for siting the anchoring tower structure upstream approximately 1.2 miles from the mouth of the Grande Ronde River

  4. Environmental assessment of facility operations at the U.S. Department of Energy Grand Junction Projects Office, Grand Junction, Colorado

    NONE

    1996-06-01

    The US Department of Energy (DOE) has prepared a sitewide environmental assessment (EA) of the proposed action to continue and expand present-day activities on the DOE Grand Junction Projects Office (GJPO) facility in Grand Junction, Colorado. Because DOE-GJPO regularly proposes and conducts many different on-site activities, DOE decided to evaluate these activities in one sitewide EA rather than in multiple, activity-specific documents. On the basis of the information and analyses presented in the EA, DOE has determined that the proposed action does not constitute a major Federal action significantly affecting the quality of the human environment, as defined by the National Environmental Policy Act (NEPA) of 1969. Therefore, preparation of an environmental impact statement is not required for facility operations, and DOE is issuing this Finding of No Significant Impact (FONSI).

  5. Environmental assessment of facility operations at the U.S. Department of Energy Grand Junction Projects Office, Grand Junction, Colorado

    1996-06-01

    The US Department of Energy (DOE) has prepared a sitewide environmental assessment (EA) of the proposed action to continue and expand present-day activities on the DOE Grand Junction Projects Office (GJPO) facility in Grand Junction, Colorado. Because DOE-GJPO regularly proposes and conducts many different on-site activities, DOE decided to evaluate these activities in one sitewide EA rather than in multiple, activity-specific documents. On the basis of the information and analyses presented in the EA, DOE has determined that the proposed action does not constitute a major Federal action significantly affecting the quality of the human environment, as defined by the National Environmental Policy Act (NEPA) of 1969. Therefore, preparation of an environmental impact statement is not required for facility operations, and DOE is issuing this Finding of No Significant Impact (FONSI)

  6. Microbial contamination and chemical toxicity of the Rio Grande

    Valles Adrian

    2004-04-01

    Full Text Available Abstract Background The Rio Grande River is the natural boundary between U.S. and Mexico from El Paso, TX to Brownsville, TX. and is one of the major water resources of the area. Agriculture, farming, maquiladora industry, domestic activities, as well as differences in disposal regulations and enforcement increase the contamination potential of water supplies along the border region. Therefore, continuous and accurate assessment of the quality of water supplies is of paramount importance. The objectives of this study were to monitor water quality of the Rio Grande and to determine if any correlations exist between fecal coliforms, E. coli, chemical toxicity as determined by Botsford's assay, H. pylori presence, and environmental parameters. Seven sites along a 112-Km segment of the Rio Grande from Sunland Park, NM to Fort Hancock, TX were sampled on a monthly basis between January 2000 and December 2002. Results The results showed great variability in the number of fecal coliforms, and E. coli on a month-to-month basis. Fecal coliforms ranged between 0–106 CFU/100 ml while E. coli ranged between 6 to > 2419 MPN. H. pylori showed positive detection for all the sites at different times. Toxicity ranged between 0 to 94% of inhibition capacity (IC. Since values above 50% are considered to be toxic, most of the sites displayed significant chemical toxicity at different times of the year. No significant correlations were observed between microbial indicators and chemical toxicity. Conclusion The results of the present study indicate that the 112-Km segment of the Rio Grande river from Sunland Park, NM to Fort Hancock, TX exceeds the standards for contact recreation water on a continuous basis. In addition, the presence of chemical toxicity in most sites along the 112-Km segment indicates that water quality is an area of concern for the bi-national region. The presence of H. pylori adds to the potential health hazards of the Rio Grande. Since no

  7. Depressurization of a spread of Brazil-Bolivia gas pipeline and the emergency repair of a weld crack in a instrument derivation at Campo Grande compression station; Despressurizacao de trecho do gasoduto Bolivia-Brazil para reparo emergencial de trinca em uma derivacao de instrumento de temperatura na Estacao de Compressao de Campo Grande - MS

    Dietrich, Carlos Ribeiro; Leite Junior, Ismael Casano [TBG - Transportadora Brasileira Gasoduto Bolivia Brasil S.A., Rio de Janeiro, RJ (Brazil)

    2005-07-01

    The purpose of this paper is to report the actions taken to repair a gas leak, at an original pressure of 100 kgf/cm{sup 2}, occurred due to a 1 1/2'' branch pipe weld crack, located on the 24'' Campo Grande - Mato Grosso do Sul Compression Station discharge pipe. This branch pipe was used to a thermo well installation and was submitted to an additional strength caused by thermo well vibration. The weld repair actions required an urgent depressurization of a 33 km spread of Bolivia-Brazil Pipeline in a timely manner, to avoid any negative impact in the operational schedule. (author)

  8. Micetomas actinomicóticos no Rio Grande do Sul: relato de quatro casos Actinomycotic mycetomas in Rio Grande do Sul: report of 4 cases

    Alberto T. Londero

    1986-03-01

    Full Text Available São relatados quatro casos de micetoma causados por Nocardia brasiliensis, ocorridos no Rio Grande do Sul. É revista a literatura rio-grandense-do-sul.Four cases of mycetoma caused by N. brasiliensis, occurring in Rio Grande do Sul (Brazil, are reported.

  9. Considerations on the manner to account for fast fracture risk in the design of PWR vessels

    Pellisier-Tanon, A.; Grandemange, J.M.

    1985-08-01

    The way followed in France for analyzing fast fracture resistance of PWR primary components is the one of a deterministic analysis with safety coefficients imposed in the fracture criteria. The study of margins towards fast fracture of the 900 MWe program vessels undertaken in 1982 includes parametric evaluations of the influence of essential variables. It has stimulated further thoughts on the level of safety to fix in the analysis methodology, on the orientations for the choice of safety factors and on the manner to introduce them in the analysis. A first chapter tries to characterize the French approach in comparison to those of other countries. A second chapter examines the manner according to which safety factors can be introduced in the deterministic analysis. It presents the principle for a logical approach accounting for the interdependency of all factors and variables. It establishes criteria for the selection of defect kind and size for the computation

  10. p21-activated Kinase1(PAK1) can promote ERK activation in a kinase independent manner

    Wang, Zhipeng; Fu, Meng; Wang, Lifeng

    2013-01-01

    204) although phosphorylation of b-Raf (Ser445) and c-Raf (Ser 338) remained unchanged. Furthermore, increased activation of the PAK1 activator Rac1 induced the formation of a triple complex of Rac1, PAK1 and Mek1, independent of the kinase activity of PAK1. These data suggest that PAK1 can stimulate...... MEK activity in a kinase independent manner, probably by serving as a scaffold to facilitate interaction of c-Raf....

  11. Fostering Scientific Literacy: Establishing Social Relevance via the Grand Challenges

    Lyford, M. E.; Myers, J. D.; Buss, A.

    2010-12-01

    Numerous studies and polls suggest the general public’s understanding of science and scientific literacy remain woefully inadequate despite repeated calls for improvement over the last 150 years. This inability to improve scientific literacy significantly is a complex problem likely driven by a number of factors. However, we argue that past calls and efforts for improving scientific literacy have failed to: 1) articulate a truly meaningful justification for society to foster a scientifically literate public; 2) provide a rationale that motivates individuals of diverse backgrounds to become scientifically literate; 3) consider the impact of personal perspective, e.g. values, beliefs, attitudes, etc., on learning; and 4) offer a relevant and manageable framework in which to define scientific literacy. For instance, past calls for improving scientific literacy, e.g. the U.S. is behind the Soviets in the space race, U.S students rank below country X in math and science, etc., have lacked justification, personal motivation and a comprehensive framework for defining scientific literacy. In these cases, the primary justification for improving science education and scientific literacy was to regain international dominance in the space race or to advance global standing according to test results. These types of calls also articulate short-term goals that are rendered moot once they have been achieved. At the same time, teaching practices have commonly failed to consider the perspectives students bring to the classroom. Many STEM faculty do not address issues of personal perspective through ignorance or the desire to avoid controversial subjects, e g. evolution, climate change. We propose that the ‘grand challenges’ (e.g., energy, climate change, antibacterial resistance, water, etc.) humankind currently faces provides a compelling framework for developing courses and curricula well-suited for improving scientific literacy. A grand challenge paradigm offers four

  12. UMTRA project water sampling and analysis plan, Grand Junction, Colorado

    1994-07-01

    Surface remedial action will be completed at the Grand Junction processing site during the summer of 1994. Results of 1993 water sampling indicate that ground water flow conditions and ground water quality at the processing site have remained relatively constant with time. Uranium concentrations in ground water continue to exceed the maximum concentration limits, providing the best indication of the extent of contaminated ground water. Evaluation of surface water quality of the Colorado River indicate no impact from uranium processing activities. No compliance monitoring at the Cheney disposal site has been proposed because ground water in the Dakota Sandstone (uppermost aquifer) is classified as limited-use (Class 111) and because the disposal cell is hydrogeologically isolated from the uppermost aquifer. The following water sampling and water level monitoring activities are planned for calendar year 1994: (i) Semiannual (early summer and late fall) sampling of six existing monitor wells at the former Grand Junction processing site. Analytical results from this sampling will be used to continue characterizing hydrogeochemical trends in background ground water quality and in the contaminated ground water area resulting from source term (tailings) removal. (ii) Water level monitoring of approximately three proposed monitor wells projected to be installed in the alluvium at the processing site in September 1994. Data loggers will be installed in these wells, and water levels will be electronically monitored six times a day. These long-term, continuous ground water level data will be collected to better understand the relationship between surface and ground water at the site. Water level and water quality data eventually will be used in future ground water modeling to establish boundary conditions in the vicinity of the Grand Junction processing site. Modeling results will be used to help demonstrate and document the potential remedial alternative of natural flushing

  13. Pacing of Paleozoic macroevolutionary rates by Milankovitch grand cycles.

    Crampton, James S; Meyers, Stephen R; Cooper, Roger A; Sadler, Peter M; Foote, Michael; Harte, David

    2018-05-29

    Periodic fluctuations in past biodiversity, speciation, and extinction have been proposed, with extremely long periods ranging from 26 to 62 million years, although forcing mechanisms remain speculative. In contrast, well-understood periodic Milankovitch climate forcing represents a viable driver for macroevolutionary fluctuations, although little evidence for such fluctuation exists except during the Late Cenozoic. The reality, magnitude, and drivers of periodic fluctuations in macroevolutionary rates are of interest given long-standing debate surrounding the relative roles of intrinsic biotic interactions vs. extrinsic environmental factors as drivers of biodiversity change. Here, we show that, over a time span of 60 million years, between 9 and 16% of the variance in biological turnover (i.e., speciation probability plus species extinction probability) in a major Early Paleozoic zooplankton group, the graptoloids, can be explained by long-period astronomical cycles (Milankovitch "grand cycles") associated with Earth's orbital eccentricity (2.6 million years) and obliquity (1.3 million years). These grand cycles modulate climate variability, alternating times of relative stability in the environment with times of maximum volatility. We infer that these cycles influenced graptolite speciation and extinction through climate-driven changes to oceanic circulation and structure. Our results confirm the existence of Milankovitch grand cycles in the Early Paleozoic Era and show that known processes related to the mechanics of the Solar System were shaping marine macroevolutionary rates comparatively early in the history of complex life. We present an application of hidden Markov models to macroevolutionary time series and protocols for the evaluation of statistical significance in spectral analysis.

  14. Information Summary, Area of Concern: Grand Calumet River, Indiana

    1991-03-01

    Page 179-183) 56 Waste Fill and Lagoon Sites Mapped Within the Grand Calumet Watershed (Source R13, Table 2-15) 57 Waste Fills of Greatest Concern...Percent Response for Single Species Sediment Bioassays from Indiana Harbor (Source RI, Table 18) 78 Aquatic Macroinvertebrates Collected from Stations 1, 2...3, 4, 5, and 12a, 3-4 May 88 (Source Rl, Table 22) 79 Aquatic Macroinvertebrates Collected from Stations 6, 7, 8, 9a, 10a, and 11, 3-4 and 19 May 88

  15. Igreja e italianidade: Rio Grande do Sul (1875-1945

    Paulo César Possamai

    1999-12-01

    Full Text Available This article analyses the position adopted by the catholic clergy concerning the italianità policy among the Italian immigrants in the State of Rio Grande do Sul. While the Carlists protected the Italian nationalism among the colonists and were inclined to a good relationship between the Catholic Church and the Kingdom of Italy, to the Capuchins the italianità was useful to preserve the catholic faith among the colonists, although they also supported the conservative point of view of the Vatican, that the liberal Italian State was the usurper of the papacy lands.

  16. GRAND DESIGN MODEL PEMBINAAN PROFESIONAL GURU BERBASIS DETERMINAN KINERJA GURU

    Bambang Budi Wiyono

    2015-08-01

    Full Text Available Abstract: A Grand Design Model of Teacher Professional Education Based on Teacher's Perfor­mace Determinant. One of the crucial factors that determines the quality of education is teachers. Thus, developing teachers' professionalism in carrying out their work is essential. This study aims at developing a grand design model of teacher professional education based on determinant factors of teachers' performance. It is a research and development study (R&D, in which data were collected through questionnaires, observations, and interviews, and analyzed using descriptive statistics, correla­tion analysis, and qualitative data analysis. The sample consists of 90 teachers and 28 headmasters selected using quota random sampling. The findings of the study show that the effective model of teacher pro­fessional education is the one conducted through five steps, namely, needs analysis, development of training and supervision programs, implementation of the programs, evaluation of the programs, and follow-ups of the programs. The development of the programs requires coordination among related in­stitutions. The implementation needs to refer to the right principles, approach, and training techniques and be supported by good facilities, media, trainers, and training places. Keywords: training model, teachers' professionalism, teachers' performance Abstrak: Grand Design Model Pembinaan Profesional Guru Berbasis Determinan Kinerja Guru. Salah satu faktor yang sangat menentukan mutu pendidikan adalah guru. Untuk itu diperlukan pening­katan profesionalisme guru dalam melaksanakan tugas. Penelitian ini bertujuan mengembangkan grand design model pembinaan profesional guru yang efektif berbasis faktor-faktor determinan kinerja guru. Penelitian menggunakan desain penelitian pengembangan. Sampel diambil sebesar 90 guru dan 28 kepala sekolah dengan quota random sampling. Data dikumpulan data kuesioner, observasi, dan wawancara. Hasil pengumpulan data dianalisis

  17. Grande Ronde Endemic Spring Chinook Project - ODFW, 2008 Annual Report.

    Patterson, Scott

    2009-04-10

    Core activities of the Grande Ronde Endemic Spring Chinook Supplementation Program (GRESCSP) are funded through the authority of the Lower Snake River Fish and Wildlife Compensation Plan (LSRCP). The LSRCP program was approved by the Water Resources Development Act of 1976, PL 94-587, Section 102, 94th Congress substantially in accordance with the Special Report, LSRCP, June 1975 on file with the Chief of Engineers. The LSRCP was prepared and submitted in compliance with the Fish and Wildlife Coordination Act of 1958, PL 85-624, 85th Congress, August 12, 1958 to mitigate for the losses of fish and wildlife caused by the construction of dams on lower Snake River. The GRESCSP is an artificial propagation program that was initiated by Bonneville Power Administrations Fish and Wildlife program in the mid 1990's. The intent of this program was to change the mitigation aspect of the LSRCP program (harvest mitigation) to an integrated supplementation program; inasmuch as, hatchery produced fish could be experimentally used as a recovery tool and fish surplus to mitigation would be available for in-place and in-kind harvest. Fish production is still authorized by the LSRCP with the original mitigation return goal of 5,860 adult spring Chinook to the project area. The GRESCSP was developed with two primary components: (1) conventional broodstock (projects 199800702; 199800703; 199800704) and (2) captive brood (projects 199801001; 199801006). The GRESCSP relies on cooperative M&E efforts from the LSRCP including setting aside the Wenaha and Minam tributaries as natural production reserves components used for reference streams. The GRESCSP, coordinated with federal and tribal partners, identifies production levels for both propagation components and weir management strategies for each of the three supplemented tributary areas within the Grande Ronde Sub-basin. The three supplemented areas are Catherine Creek, Lostine River, and upper Grande Ronde River. Lookingglass

  18. Los milagros de la Mamá Grande

    Palomares Güells, Laura

    2017-01-01

    Análisis de la figura mítica de Carmen Balcells desde el arquetipo de "la Mamá Grande" con el que se la ha identificado en numerosas ocasiones, para observar la relevancia de Balcells en la memoria editorial colectiva del boom latinoamericano. Anàlisi de la figura mítica de Carmen Balcells des de l'arquetip de la "Mamà Gran" amb el que se l'ha identificat en nombroses ocasions per a observar la rellevància de Balcells en la memòria editorial col·lectiva del boom llatinoamericà.

  19. KLEPSUDRA: How the Rio Grande Treaty Increased Instability in Mexico

    2008-05-09

    advantages, not the least of which is having an agency that can operate on the peer level with Mexico’s national water agency (Comisión Nacional del Agua ...Help Wanted’ ads,” USA Today, 25 April 08, sec. A, p. 8. 77 Manwaring (2007), 9-11, 24-25, 34-35. 78 Contamination levels along the border areas and in...the Rio Grande River after NAFTA has been extensively researched and documented. Recent testing indicates extreme fecal contamination is exposing

  20. Google Science Fair 2012 : Grand Prize Winner Brittany Wenger

    Maximilien Brice

    2012-01-01

    17-18 age category AND Grand Prize Winner: Brittany Wenger (USA)—“Global Neural Network Cloud Service for Breast Cancer.” Brittany’s project harnesses the power of the cloud to help doctors accurately diagnose breast cancer. Brittany built an application that compares individual test results to an extensive dataset stored in the cloud, allowing doctors to assess tumors using a minimally-invasive procedure. Brittany Michelle Wenger, and her mother, passed through the CERN Control Centre accompanied by Mike Lamont, CERN Beams Department, Operation Group Leader.

  1. Softening the supersymmetric flavor problem in orbifold grand unified theories

    Kajiyama, Yuji; Terao, Haruhiko; Kubo, Jisuke

    2004-01-01

    The infrared attractive force of the bulk gauge interactions is applied to soften the supersymmetric flavor problem in the orbifold SU(5) grand unified theory of Kawamura. Then this force aligns in the infrared regime the soft supersymmetry breaking terms out of their anarchical disorder at a fundamental scale, in such a way that flavor-changing neutral currents as well as dangerous CP-violating phases are suppressed at low energies. It is found that this dynamical alignment is sufficiently good compared with the current experimental bounds, as long as the diagonalization matrices of the Yukawa couplings are CKM-like

  2. El poder de las grandes empresas petroleras: 19001950

    Jesús Mora Contreras

    2003-01-01

    Entre 1900 y 1950 las grandes corporaciones petroleras internacionales lograron imponer a los propietarios del recurso natural en el Medio Oriente y en Venezuela las normas y procedimientos que regulaban contractual y legalmente las actividades de exploración y explotación de petróleo. Lograron además crear un cartel interna-cional de empresas productoras para dividirse el mercado entre ellas e imponer a los consumidores un sistema de fijación del precio mundial del crudo.

  3. Stability of mass hierarchy in locally supersymmetric grand unification

    Nishino, H.; Helayel-Neto, J.A.; Koh, I.G.

    1984-06-01

    Some locally supersymmetric SU(5) grand unified models with a sliding singlet and two pairs of 5sub(tilde) and 5sub(tilde)* Higgs multiplets are considered from the viewpoint of universal baryon asymmetry and the one-loop stability of mass hierarchy. A new mechanism based on ''sliding singlet reflection symmetry'' to avoid the problem of the mass hierarchical stability is proposed. The stability is shown up to two-loop levels for some models. All order stability is also discussed. (author)

  4. Grande Ronde Basin Fish Habitat Enhancement Project : 2000 Annual Report.

    McGowan, Vance R.; Powell, Russ M.; Stennfeld, Scott P.

    2001-04-01

    On July 1, 1984 the Bonneville Power Administration and the Oregon Department of Fish and Wildlife entered into an agreement to initiate fish habitat enhancement work in the Joseph Creek subbasin of the Grande Ronde River Basin in northeast Oregon. In July of 1985 the Upper and Middle Grande Ronde River, and Catherine Creek subbasins were included in the intergovernmental contract, and on March 1, 1996 the Wallowa River subbasin was added. The primary goal of ''The Grande Ronde Basin Fish Habitat Enhancement Project'' is to access, create, improve, protect, and restore riparian and instream habitat for anadromous salmonids, thereby maximizing opportunities for natural fish production within the basin. This project provided for implementation of Program Measure 703 (C)(1), Action Item 4.2 of the Northwest Power Planning Council's Columbia River Basin Fish and Wildlife Program (NPPC, 1987), and continues to be implemented as offsite mitigation for mainstem fishery losses caused by the Columbia River hydro-electric system. All work conducted by the Oregon Department of Fish and Wildlife is on private lands and therefore requires that considerable time be spent developing rapport with landowners to gain acceptance of, and continued cooperation with this program throughout 10-15 year lease periods. This project calls for passive regeneration of habitat, using riparian enclosure fencing as the primary method to restore degraded streams to a normative condition. Active remediation techniques using plantings, off-site water developments, site-specific instream structures, or whole channel alterations are also utilized where applicable. Individual projects contribute to and complement ecosystem and basin-wide watershed restoration efforts that are underway by state, federal, and tribal agencies, and local watershed councils. Work undertaken during 2000 included: (1) Implementing 2 new projects in the Grande Ronde drainage, and retrofitting one old

  5. Vigilando la Calidad del Agua de los Grandes Rios de la Nacion: El Programa NASQAN del Rio Grande (Rio Bravo del Norte)

    Lurry, Dee L.; Reutter, David C.; Wells, Frank C.; Rivera, M.C.; Munoz, A.

    1998-01-01

    La Oficina del Estudio Geologico de los Estados Unidos (U.S. Geological Survey, 0 USGS) ha monitoreado la calidad del agua de la cuenca del Rio Grande (Rio Bravo del Norte) desde 1995 como parte de la rediseiiada Red Nacional para Contabilizar la Calidad del Agua de los Rios (National Stream Quality Accounting Network, o NASOAN) (Hooper and others, 1997). EI programa NASOAN fue diseiiado para caracterizar las concentraciones y el transporte de sedimento y constituyentes quimicos seleccionados, encontrados en los grandes rios de los Estados Unidos - incluyendo el Misisipi, el Colorado y el Columbia, ademas del Rio Grande. En estas cuatro cuencas, el USGS opera actualmente (1998) una red de 40 puntos de muestreo pertenecientes a NASOAN, con un enfasis en cuantificar el flujo en masa (la cantidad de material que pasa por la estacion, expresado en toneladas por dial para cada constituyente. Aplicacando un enfoque consistente, basado en la cuantificacion de flujos en la cuenca del Rio Grande, el programa NASOAN esta generando la informacion necesaria para identificar fuentes regionales de diversos contaminantes, incluyendo sustancias qui micas agricolas y trazas elementos en la cuenca. EI efecto de las grandes reservas en el Rio Grande se puede observar segun los flujos de constituyentes discurren a 10 largo del rio. EI analisis de los flujos de constituyentes a escala de la cuenca proveera los medios para evaluar la influencia de la actividad humana sobre las condiciones de calidad del agua del Rio Grande.

  6. Renovation, overpainting, inpainting: strategies of the painter-restorer in Portugal, from the 16th to 19th century. Ideological reasons for the iconoclast and the iconofylic practices, or the concept of «utilitarian restoration» versus «scientific restoration»

    Vitor Serrão

    2006-01-01

    Full Text Available The study of Portuguese art during the Modern Age, and the very recurrent activity of «painting restoration», concludes that the dominant practice then referenced as «retoque» (inpainting, «repinte» (overpainting, «renovação» (renovation and even «restauro» (restoration, herein designated as «corrective and utilitarian restoration», was common to the best artists during the period between the 16th and the 18th centuries.Those interventions, which were commended by the church and the nobility, were nearly always considered a noble activity. The terminologies and the techniques then used are explained as well as the various reasons (moral, theological, aesthetic, decorous, and others for undertaking that type of work, which is assumed as the precursor of the 19th century «scientific restoration». «Renovation» criteria, iconoclast and iconofylic practice related to this «utilitarian restoration» are discussed herein and important figures of Portuguese painting such as Francisco Venegas, Diogo Teixeira, André Reinoso, António Pereira Ravasco, Francisco Vieira Lusitano, amongst others, were also «painters-restorers» within those existing concepts. It is further reminded that to be a «painter-restorer», always in the perspective of an artistic «re-creation», was a motive for added pride for artists such as Pietro Guarienti,Vieira Lusitano, Pereira Pegado or Inácio Coelho Valente.

  7. Metal stressors consistently modulate bacterial conjugal plasmid uptake potential in a phylogenetically conserved manner

    Klümper, Uli; Dechesne, Arnaud; Riber, Leise

    2017-01-01

    The environmental stimulants and inhibitors of conjugal plasmid transfer in microbial communities are poorly understood. Specifically, it is not known whether exposure to stressors may cause a community to alter its plasmid uptake ability. We assessed whether metals (Cu, Cd, Ni, Zn) and one metal...... that community permissiveness is sensitive to metal(loid) stress in a manner that is both partially consistent across stressors and phylogenetically conserved.The ISME Journal advance online publication, 2 August 2016; doi:10.1038/ismej.2016.98....

  8. The description of morality and manners in Vsevolod Solovyov’s short prose

    Nikolsky Evgeny Vladimirovich

    2013-01-01

    This article contains a genre specificity of short prose by Vsevolod Solovyov, whose work is devoted to the Russian history between the 18th and 19th centuries. According to professor N.L. Vershinina, the author distinguishes the difference between the description of morality and manners. The main difference is in the presence of author’s point of view on the describing occurrences. In this case, such works are considered to be a kind of morality, which characterizes Solovyov’s works. Showing...

  9. The description of morality and manners in Vsevolod Solovyov’s short prose

    Nikolsky Evgeny Vladimirovich

    2013-06-01

    Full Text Available This article contains a genre specificity of short prose by Vsevolod Solovyov, whose work is devoted to the Russian history between the 18th and 19th centuries. According to professor N.L. Vershinina, the author distinguishes the difference between the description of morality and manners. The main difference is in the presence of author’s point of view on the describing occurrences. In this case, such works are considered to be a kind of morality, which characterizes Solovyov’s works. Showing every-day life, he examined the process of turning barbarism into a civilizing society.

  10. Parental overprotection engenders dysfunctional attitudes about achievement and dependency in a gender-specific manner.

    Otani, Koichi; Suzuki, Akihito; Matsumoto, Yoshihiko; Shibuya, Naoshi; Sadahiro, Ryoichi; Enokido, Masanori

    2013-12-24

    It has been suggested that dysfunctional attitudes, cognitive vulnerability to depression, have developmental origins. The present study examined the effects of parental rearing on dysfunctional attitudes in three areas of life with special attention to gender specificity. The subjects were 665 Japanese healthy volunteers. Dysfunctional attitudes were assessed by the 24-item Dysfunctional Attitude Scale, which has the Achievement, Dependency and Self-control subscales. Perceived parental rearing was assessed by the Parental Bonding Instrument, which has the Care and Protection subscales. Higher scores of the Achievement (β = 0.293, p overprotection engenders dysfunctional attitudes about achievement and dependency in a gender-specific manner.

  11. Tissue transglutaminase inhibits the TRPV5-dependent calcium transport in an N-glycosylation-dependent manner

    Boros, Sandor; Xi, Qi; Dimke, Henrik Anthony

    2011-01-01

    Tissue transglutaminase (tTG) is a multifunctional Ca(2+)-dependent enzyme, catalyzing protein crosslinking. The transient receptor potential vanilloid (TRPV) family of cation channels was recently shown to contribute to the regulation of TG activities in keratinocytes and hence skin barrier form......, these observations imply that tTG is a novel extracellular enzyme inhibiting the activity of TRPV5. The inhibition of TRPV5 occurs in an N-glycosylation-dependent manner, signifying a common final pathway by which distinct extracellular factors regulate channel activity....

  12. A Brief Analysis on The Mannerism of Strange Stories of A Chinese Studio by Pu Songling

    Andyni Khosasih

    2012-10-01

    Full Text Available Strange Stories of a Chinese Studio, commonly known as 聊斋 (Liaozhai is a short novel written in classical Chinese from Qing dynasty. This novel was written in 1680, year 19 of Emperor Kangxi’s reign. The novel has 491 chapters. Article explored Pu Songling’s mannerism, such as the contents, material collection, innovation of artistic literary elements and images of women. It can be concluded that  the novel reflects the broadness of humanistic world and thoroughly describes images of women. It broke through the restriction of thoughts in feudalism society.  

  13. The Tragedy of Migrants. Gabriele Del Grande's Reportage

    Luigi Franchi

    2017-11-01

    Full Text Available L’espressione "Tragedia dei migranti" che ciclicamente compare nei notiziari televisivi, seppur evocando la categoria del tragico, non suscita nessuno dei sentimenti che caratterizzano questa forma di spettacolo. Lo spettatore infatti è portato a considerare i naufragi nel Mediterraneo il frutto di un destino ineluttabile, senza quindi intravedere alcuna possibilità da parte sua di intervenire sulla realtà. Mamadou va a morire e Il mare di mezzo di Gabriele Del Grande dimostrano come i naufragi dei migranti nel Mediterraneo non siano parte del disegno divino di un deus absconditus, ma una delle drammatiche conseguenze della crisi economica della contemporaneità. Esibendo i meccanismi sottesi al fenomeno della migrazione, l’autore mostra i presupposti razionali sui quali questa si fonda e suggerisce come i suoi esiti drammatici possano essere contrastati a livello individuale e collettivo. Questo articolo si propone di dotare di un senso più pieno l’espressione "tragedia dei migranti": per fare ciò si rintraccerà all’interno dei reportage la riemersione di alcuni topoi della tragedia greca. Verrà inoltre individuata tra gli individui incontrati da Del Grande nei suoi viaggi e i personaggi della tragedia greca una serie di analogie in grado di restituire alla condizione del migrante una reale potenzialità tragica.

  14. Grand Unification as a Bridge Between String Theory and Phenomenology

    Pati, Jogesh C.

    2006-06-09

    In the first part of the talk, I explain what empirical evidence points to the need for having an effective grand unification-like symmetry possessing the symmetry SU(4)-color in 4D. If one assumes the premises of a future predictive theory including gravity--be it string/M theory or a reincarnation--this evidence then suggests that such a theory should lead to an effective grand unification-like symmetry as above in 4D, near the string-GUT-scale, rather than the standard model symmetry. Advantages of an effective supersymmetric G(224) = SU(2){sub L} x SU(2){sub R} x SU(4){sup c} or SO(10) symmetry in 4D in explaining (1) observed neutrino oscillations, (2) baryogenesis via leptogenesis, and (3) certain fermion mass-relations are noted. And certain distinguishing tests of a SUSY G(224) or SO(10)-framework involving CP and flavor violations (as in {mu} {yields} e{gamma}, {tau} {yields} {mu}{gamma}, edm's of the neutron and the electron) as well as proton decay are briefly mentioned. Recalling some of the successes we have had in our understanding of nature so far, and the current difficulties of string/M theory as regards the large multiplicity of string vacua, some comments are made on the traditional goal of understanding vis a vis the recently evolved view of landscape and anthropism.

  15. Geomorphology of plutonium in the Northern Rio Grande

    Graf, W.L. [Arizona Univ., Tempe, AZ (United States). Dept., of Geography

    1993-03-01

    Nearly all of the plutonium in the natural environment of the Northern Rio Grande is associated with soils and sediment, and river processes account for most of the mobility of these materials. A composite regional budget for plutonium based on multi-decadal averages for sediment and plutonium movement shows that 90 percent of the plutonium moving into the system is from atmospheric fallout. The remaining 10 percent is from releases at Los Alamos. Annual variation in plutonium flux and storage exceeds 100 percent. The contribution to the plutonium budget from Los Alamos is associated with relatively coarse sediment which often behaves as bedload in the Rio Grande. Infusion of these materials into the main stream were largest in 1951, 1952, 1957, and 1968. Because of the schedule of delivery of plutonium to Los Alamos for experimentation and weapons manufacturing, the latter two years are probably the most important. Although the Los Alamos contribution to the entire plutonium budget was relatively small, in these four critical years it constituted 71--86 percent of the plutonium in bedload immediately downstream from Otowi.

  16. Cosmic Ray Physics with the KASCADE-Grande Observatory

    Arteaga-Velázquez, J. C.; Apel, W. D.; Bekk, K.; Bertaina, M.; Blümer, J.; Bozdog, H.; Brancus, I. M.; Cantoni, E.; Chiavassa, A.; Cossavella, F.; Daumiller, K.; de Souza, V.; Di Pierro, F.; Doll, P.; Engel, R.; Fuhrmann, D.; Gherghel-Lascu, A.; Gils, H. J.; Glasstetter, R.; Grupen, C.; Haungs, A.; Heck, D.; Hörandel, J. R.; Huege, T.; Kampert, K.-H.; Kang, D.; Klages, H. O.; Link, K.; Łuczak, P.; Mathes, H. J.; Mayer, H. J.; Milke, J.; Mitrica, B.; Morello, C.; Oehlschläger, J.; Ostapchenko, S.; Pierog, T.; Rebel, H.; Roth, M.; Schieler, H.; Schoo, S.; Schröder, F. G.; Sima, O.; Toma, G.; Trinchero, G. C.; Ulrich, H.; Weindl, A.; Wochele, J.; Zabierowski, J.

    The existence of a knee at a few PeV in the all-particle cosmic ray energy spectrum has been well established by several experiments but its physical origin has eluded researches for a long time. It is believed that keys to disentangle the mystery could be found in the spectrum and the composition of cosmic rays between 1 PeV and 1 EeV. A first detailed look into the elemental chemical abundances of cosmic rays in this energy regime was provided by both the KASCADE and the KASCADE-Grande experiments. Their measurements opened the door to a wealth of new data on the subject, which led to the discovery of new structures in the all-particle energy spectrum and the confirmation of knee-like features in the spectra of individual mass groups, as well as the observation of an unexpected ankle-like structure at around 100 PeV in the flux of the light component of cosmic rays. In this contribution, early findings with the KASCADE-Grande experiment will be reviewed and then a short update on the analyses currently performed with the data of the observatory will be presented.

  17. Mandibular fracture cases in Pelotas, Rio Grande do Sul, Brazil

    Rafael Silva da Silva

    2009-10-01

    Full Text Available Objectives: To analyze the data in the literature, which show a high incidence of mandibular fractures. The aim of this research was to elucidate the context in which these fractures occur among patients attended at the first aid center of “Pronto Socorro Municipal de Pelotas”, Rio Grande do Sul, Brazil. Methods: From the records referring to the period of June, 2001 to August, 2007, there were 1 345 patients with facial fractures. Of this total, 116 patients with mandibular fracture were selected for this study and the items analysed were: age, gender, mandibular fracture site, etiology and period of the year. Results: It was found that 86.2% of the sample were men. The most prevalent age was 20 to 29 years old representing 36.2%, and the most affected mandibular sites were the body, with 29 cases (25%, and the condyle, with 26 cases (22.4%. The most common cause of fractures was the physical aggression representing 37.1%. The period of the year with the highest incidence of mandibular fractures was the summer, with 38 cases (32.8%. Conclusion: It was therefore observed that the patients with mandibular fracture assisted at Pronto-Socorro Municipal de Pelotas, Rio Grande do Sul, Brazil, were generally men, 20 to 29 years old with mandibular body fracture and they were victims of physical aggression.

  18. Saturn's Magnetic Field from the Cassini Grand Finale orbits

    Dougherty, M. K.; Cao, H.; Khurana, K. K.; Hunt, G. J.; Provan, G.; Kellock, S.; Burton, M. E.; Burk, T. A.

    2017-12-01

    The fundamental aims of the Cassini magnetometer investigation during the Cassini Grand Finale orbits were determination of Saturn's internal planetary magnetic field and the rotation rate of the deep interior. The unique geometry of the orbits provided an unprecedented opportunity to measure the intrinsic magnetic field at close distances never before encountered. The surprising close alignment of Saturn's magnetic axis with its spin axis, known about since the days of Pioneer 11, has been a focus of the team's analysis since Cassini Saturn Orbit Insertion. However, the varying northern and southern magnetospheric planetary period oscillations, which fill the magnetosphere, has been a factor in masking the field signals from the interior. Here we describe an overview of the magnetometer results from the Grand Finale orbits, including confirmation of the extreme axisymmetric nature of the planetary magnetic field, implications for knowledge of the rotation rate and the behaviour of external magnetic fields (arising from the ring current, field aligned currents both at high and low latitudes and the modulating effect of the planetary period oscillations).

  19. Wintertime Boundary Layer Structure in the Grand Canyon.

    Whiteman, C. David; Zhong, Shiyuan; Bian, Xindi

    1999-08-01

    Wintertime temperature profiles in the Grand Canyon exhibit a neutral to isothermal stratification during both daytime and nighttime, with only rare instances of actual temperature inversions. The canyon warms during daytime and cools during nighttime more or less uniformly through the canyon's entire depth. This weak stability and temperature structure evolution differ from other Rocky Mountain valleys, which develop strong nocturnal inversions and exhibit convective and stable boundary layers that grow upward from the valley floor. Mechanisms that may be responsible for the different behavior of the Grand Canyon are discussed, including the possibility that the canyon atmosphere is frequently mixed to near-neutral stratification when cold air drains into the top of the canyon from the nearby snow-covered Kaibab Plateau. Another feature of canyon temperature profiles is the sharp inversions that often form near the canyon rims. These are generally produced when warm air is advected over the canyon in advance of passing synoptic-scale ridges.Wintertime winds in the main canyon are not classical diurnal along-valley wind systems. Rather, they are driven along the canyon axis by the horizontal synoptic-scale pressure gradient that is superimposed along the canyon's axis by passing synoptic-scale weather disturbances. They may thus bring winds into the canyon from either end at any time of day.The implications of the observed canyon boundary layer structure for air pollution dispersion are discussed.

  20. O DISCURSO DO MARKETING DE LUGAR E OS GRANDES EVENTOS

    Michel Nicolau Netto

    Full Text Available Os grandes eventos se globalizam na mesma medida em que proliferam os lugares promovidos como marcas. Embora autônomos, esses processos estão relacionados ao se fundarem numa visão de que os lugares devem competir na globalização e que a competição deve se dar a partir de suas imagens. Esse tipo de competição se embasa num discurso produzido por publicitários de marketing de lugar, que tanto manuseiam formas simbólicas construídas como identidades coletivas, quanto se engajam na produção de novos elementos, de forma a configurá-los, tal qual as marcas de produtos, como diferencial competitivo. Neste artigo, investigo a atuação desses publicitários, compreendidos como artífices de um “senso comum planetário” que ressignifica a imagem do lugar a partir de concepção de uma marca. Serão aqui analisados os pressupostos desse discurso, suas instâncias de legitimidade e sua relação com os grandes eventos, que devem ser entendidos como espaços de consagração e circulação do discurso do marketing de lugar.

  1. Multivariable extrapolation of grand canonical free energy landscapes

    Mahynski, Nathan A.; Errington, Jeffrey R.; Shen, Vincent K.

    2017-12-01

    We derive an approach for extrapolating the free energy landscape of multicomponent systems in the grand canonical ensemble, obtained from flat-histogram Monte Carlo simulations, from one set of temperature and chemical potentials to another. This is accomplished by expanding the landscape in a Taylor series at each value of the order parameter which defines its macrostate phase space. The coefficients in each Taylor polynomial are known exactly from fluctuation formulas, which may be computed by measuring the appropriate moments of extensive variables that fluctuate in this ensemble. Here we derive the expressions necessary to define these coefficients up to arbitrary order. In principle, this enables a single flat-histogram simulation to provide complete thermodynamic information over a broad range of temperatures and chemical potentials. Using this, we also show how to combine a small number of simulations, each performed at different conditions, in a thermodynamically consistent fashion to accurately compute properties at arbitrary temperatures and chemical potentials. This method may significantly increase the computational efficiency of biased grand canonical Monte Carlo simulations, especially for multicomponent mixtures. Although approximate, this approach is amenable to high-throughput and data-intensive investigations where it is preferable to have a large quantity of reasonably accurate simulation data, rather than a smaller amount with a higher accuracy.

  2. Predictive Temperature Equations for Three Sites at the Grand Canyon

    McLaughlin, Katrina Marie Neitzel

    Climate data collected at a number of automated weather stations were used to create a series of predictive equations spanning from December 2009 to May 2010 in order to better predict the temperatures along hiking trails within the Grand Canyon. The central focus of this project is how atmospheric variables interact and can be combined to predict the weather in the Grand Canyon at the Indian Gardens, Phantom Ranch, and Bright Angel sites. Through the use of statistical analysis software and data regression, predictive equations were determined. The predictive equations are simple or multivariable best fits that reflect the curvilinear nature of the data. With data analysis software curves resulting from the predictive equations were plotted along with the observed data. Each equation's reduced chi2 was determined to aid the visual examination of the predictive equations' ability to reproduce the observed data. From this information an equation or pair of equations was determined to be the best of the predictive equations. Although a best predictive equation for each month and season was determined for each site, future work may refine equations to result in a more accurate predictive equation.

  3. Geomorphology of plutonium in the Northern Rio Grande

    Graf, W.L.

    1993-03-01

    Nearly all of the plutonium in the natural environment of the Northern Rio Grande is associated with soils and sediment, and river processes account for most of the mobility of these materials. A composite regional budget for plutonium based on multi-decadal averages for sediment and plutonium movement shows that 90 percent of the plutonium moving into the system is from atmospheric fallout. The remaining 10 percent is from releases at Los Alamos. Annual variation in plutonium flux and storage exceeds 100 percent. The contribution to the plutonium budget from Los Alamos is associated with relatively coarse sediment which often behaves as bedload in the Rio Grande. Infusion of these materials into the main stream were largest in 1951, 1952, 1957, and 1968. Because of the schedule of delivery of plutonium to Los Alamos for experimentation and weapons manufacturing, the latter two years are probably the most important. Although the Los Alamos contribution to the entire plutonium budget was relatively small, in these four critical years it constituted 71--86 percent of the plutonium in bedload immediately downstream from Otowi

  4. Grand Unification as a Bridge Between String Theory and Phenomenology

    Pati, Jogesh C.

    In the first part of this paper, we explain what empirical evidence points to the need for having an effective grand unification-like symmetry possessing the symmetry SU(4)-color in 4D. If one assumes the premises of a future predictive theory including gravity — be it string/M-theory or a reincarnation — this evidence then suggests that such a theory should lead to an effective grand unification-like symmetry as above in 4D, near the string-GUT-scale, rather than the standard model symmetry. Advantages of an effective supersymmetric G(224) = SU(2)L × SU(2)R × SU(4)c or SO(10) symmetry in 4D in explaining (i) observed neutrino oscillations, (ii) baryogenesis via leptogenesis, and (iii) certain fermion mass-relations are noted. And certain distinguishing tests of a SUSY G(224) or SO(10)-framework involving CP and flavor violations (as in μ → eγ, τ → μγ, edm's of the neutron and the electron) as well as proton decay are briefly mentioned. Recalling some of the successes we have had in our understanding of nature so far, and the current difficulties of string/M-theory as regards the large multiplicity of string vacua, some comments are made on the traditional goal of understanding vis a vis the recently evolved view of landscape and anthropism.

  5. Grand Unification as a Bridge Between String Theory and Phenomenology

    Pati, J

    2006-01-01

    In the first part of the talk, I explain what empirical evidence points to the need for having an effective grand unification-like symmetry possessing the symmetry SU(4)-color in 4D. If one assumes the premises of a future predictive theory including gravity--be it string/M theory or a reincarnation--this evidence then suggests that such a theory should lead to an effective grand unification-like symmetry as above in 4D, near the string-GUT-scale, rather than the standard model symmetry. Advantages of an effective supersymmetric G(224) = SU(2) L x SU(2) R x SU(4) c or SO(10) symmetry in 4D in explaining (1) observed neutrino oscillations, (2) baryogenesis via leptogenesis, and (3) certain fermion mass-relations are noted. And certain distinguishing tests of a SUSY G(224) or SO(10)-framework involving CP and flavor violations (as in μ → eγ, τ → μγ, edm's of the neutron and the electron) as well as proton decay are briefly mentioned. Recalling some of the successes we have had in our understanding of nature so far, and the current difficulties of string/M theory as regards the large multiplicity of string vacua, some comments are made on the traditional goal of understanding vis a vis the recently evolved view of landscape and anthropism

  6. Measurement and reproduction accuracy of computer-controlled grand pianos

    Goebl, Werner; Bresin, Roberto

    2003-10-01

    The recording and reproducing capabilities of a Yamaha Disklavier grand piano and a Bösendorfer SE290 computer-controlled grand piano were tested, with the goal of examining their reliability for performance research. An experimental setup consisting of accelerometers and a calibrated microphone was used to capture key and hammer movements, as well as the acoustic signal. Five selected keys were played by pianists with two types of touch (``staccato'' and ``legato''). Timing and dynamic differences between the original performance, the corresponding MIDI file recorded by the computer-controlled pianos, and its reproduction were analyzed. The two devices performed quite differently with respect to timing and dynamic accuracy. The Disklavier's onset capturing was slightly more precise (+/-10 ms) than its reproduction (-20 to +30 ms); the Bösendorfer performed generally better, but its timing accuracy was slightly less precise for recording (-10 to 3 ms) than for reproduction (+/-2 ms). Both devices exhibited a systematic (linear) error in recording over time. In the dynamic dimension, the Bösendorfer showed higher consistency over the whole dynamic range, while the Disklavier performed well only in a wide middle range. Neither device was able to capture or reproduce different types of touch.

  7. Probing the design of grand unification through conservation laws

    Pati, J.C.

    1981-01-01

    The purpose of this talk is to note a few special consequences of gauging ''maximal'' quark-lepton symmetries such as SO(16), which is the maximal symmetry for a single family of fermions. Within these symmetries, violations for B, L and F are spontaneous rather than explicit. Furthermore these symmetries as a rule permit intermediate mass scales approx.(10 3 -10 6 GeV) and (10 8 -10 11 GeV) filling the so-called grand plateau between 10 2 and 10 15 GeV. It has been shown in earlier papers that within these symmetries proton may decay via four alternative models: i.e. proton→one or three leptons or antileptons plus mesons; some of which can coexist. It is now observed that even n-n-bar oscillations can coexist with (B-L) conserving proton-decays of the type p→e + π 0 etc. without posing any conflict with the cosmological generation of baryon-excess; both these processes can possess measurable strengths so as to be amenable to forthcoming searches. Search for alternative decay modes of proton and n-n-bar oscillations, even as processes in second and third generation experiments, would provide valuable information on the question of intermediate mass-scales and thereby on the design of grand unification

  8. Towards a grand deal on subsidies and climate change

    Moor, Andre de

    2001-01-01

    Recent studies have identified public subsidies as a principal cause of unsustainable development. Worldwide, governments are spending up to $US950 billion a year on subsidies. Many of these public subsidies fail to serve their purpose and in fact, often turn out as policy failures as they further distort trade and cause environmental harm. The energy sector is among the most subsidized sectors in the world, receiving over $US240 billion per annum of public subsidies. This article highlights current energy subsidies and their implications. The article examines: (i) the global size and distribution of energy subsidies in industrialized and developing countries; (ii) the impact of these subsidies on the economy, equity and the environment ana their role as barriers for sustainable development; (iii) the political economy behind public subsidies and the various political and institutional barriers and lock-in mechanisms that cause subsidies to become entrenched in economic and public structures; and (iv) proposals for effective subsidy reform in energy policies, suggesting a global strategy to eliminate energy subsidies. OECD governments are in a position to take the lead, and the UN Framework Convention on Climate Change presents an excellent opportunity of striking a political grand deal and linking the reform of energy subsidies to a meaningful participation of developing countries to the Kyoto Protocol. Moreover, if sinks are to be included in the clean development mechanism (CDM), it is crucial to include the removal of forestry subsidies in the grand deal. (author)

  9. The New Totalitarians: Social Identities and Radical Islamist Political Grand Strategy

    Macdonald, Douglas J

    2007-01-01

    ... of the ideologically-driven grand political strategy of the Islamist extremists, which represents a totalitarian, transnational, and, in many versions, universalist social revolutionary movement...

  10. The Nature of Grand Minima and Maxima from Fully Nonlinear Flux Transport Dynamos

    Inceoglu, Fadil; Arlt, Rainer [Leibniz-Institute for Astrophysics Potsdam, An der Sternwarte 16, D-14482, Potsdam (Germany); Rempel, Matthias, E-mail: finceoglu@aip.de [High Altitude Observatory, National Center for Atmospheric Research, P.O. Box 3000, Boulder, CO 80307 (United States)

    2017-10-20

    We aim to investigate the nature and occurrence characteristics of grand solar minimum and maximum periods, which are observed in the solar proxy records such as {sup 10}Be and {sup 14}C, using a fully nonlinear Babcock–Leighton type flux transport dynamo including momentum and entropy equations. The differential rotation and meridional circulation are generated from the effect of turbulent Reynolds stress and are subjected to back-reaction from the magnetic field. To generate grand minimum- and maximum-like periods in our simulations, we used random fluctuations in the angular momentum transport process, namely the Λ-mechanism, and in the Babcock–Leighton mechanism. To characterize the nature and occurrences of the identified grand minima and maxima in our simulations, we used the waiting time distribution analyses, which reflect whether the underlying distribution arises from a random or a memory-bearing process. The results show that, in the majority of the cases, the distributions of grand minima and maxima reveal that the nature of these events originates from memoryless processes. We also found that in our simulations the meridional circulation speed tends to be smaller during grand maximum, while it is faster during grand minimum periods. The radial differential rotation tends to be larger during grand maxima, while it is smaller during grand minima. The latitudinal differential rotation, on the other hand, is found to be larger during grand minima.

  11. Bringing Seismology's Grand Challenges to the Undergraduate Classroom

    Benoit, M. H.; Taber, J.; Hubenthal, M.

    2011-12-01

    The "Seismological Grand Challenges in Understanding Earth's Dynamic Systems," a community-written long-range science plan for the next decade, poses 10 questions to guide fundamental seismological research. Written in an approachable fashion suitable for policymakers, the broad questions and supporting discussion contained in this document offer an ideal framework for the development of undergraduate curricular materials. Leveraging this document, we have created a collection of inquiry-based classroom modules that utilize authentic data to modernize seismological instruction in 100 and 200 level undergraduate courses. The modules not only introduce undergraduates to the broad questions that the seismological community seeks to answer in the future but also showcase the numerous areas where modern seismological research is actively contributing to our understanding of fundamental Earth processes. To date 6 in-depth explorations that correspond to the Grand Challenges document have been developed. The specific topics for each exploration were selected to showcase modern seismological research while also covering topics commonly included in the curriculum of these introductory classes. Examples of activities that have been created and their corresponding Grand Challenge include: -A guided inquiry that introduces students to episodic tremor and slip and compares the GPS and seismic signatures of ETS with those produced from standard tectonic earthquakes (Grand Challenge "How do faults slip?"). - A laboratory exercise where students engage in b-value mapping of volcanic earthquakes to assess potential eruption hazards (How do magmas ascend and erupt?). - A module that introduce students to glacial earthquakes in Greenland and compares their frequency and spatial distribution to tectonic earthquakes (How do processes in the ocean and atmosphere interact with the solid Earth?). What is the relationship between stress and strain in the lithosphere? - An activity that

  12. Indicadores sintéticos de calidad ambiental: un modelo general para grandes zonas urbanas

    Luis Escobar

    2006-08-01

    Full Text Available En este artículo se define el índice de calidad ambiental (ICA como una variable latente determinada por un conjunto de factores que lo afectan de manera positiva y negativa. Partimos de la hipótesis de la no homogeneidad ambiental del territorio urbano, y nos proponemos definir un modelo general para la estimación del ICA a partir de la construcción de un sistema de indicadores simples y su aplicación en grandes ciudades. De este artículo se deriva información importante para que el planificador y el gestor puedan priorizar la asignación de recursos económicos, no sólo de manera diferencial entre comunas, sino por el tipo de recursos o variables ambientales que más inciden en la calidad ambientalThis paper defines the index of environmental quality (ICA as a latent variable determined by a group of factor that affects it in a positive and negative manner. Setting off from the hypothesis of non environmental homogenous pertaining to urban territory, and following the construction of a system of simple indicators and its application in larges city. The most influential factors in the determination of the ICA by each comuna are established as well. Consequently, important information is derived, which will enable the planner and environmental agent to prioritize the assignation of economic resources, not only in a differential way among comunas but for the sort of resources or environmental variables that most affect the quality of environment

  13. Dealing with variability in water availability: the case of the Verde Grande River basin, Brazil

    B. Collischonn

    2014-09-01

    Full Text Available This paper presents a water resources management strategy developed by the Brazilian National Water Agency (ANA to cope with the conflicts between water users in the Verde Grande River basin, located at the southern border of the Brazilian semi-arid region. The basin is dominated by water-demanding fruit irrigation agriculture, which has grown significantly and without adequate water use control, over the last 30 years. The current water demand for irrigation exceeds water availability (understood as a 95 % percentile of the flow duration curve in a ratio of three to one, meaning that downstream water users are experiencing more frequent water shortages than upstream ones. The management strategy implemented in 2008 has the objective of equalizing risk for all water users and consists of a set of rules designed to restrict water withdrawals according to current river water level (indicative of water availability and water demand. Under that rule, larger farmers have proportionally larger reductions in water use, preserving small subsistence irrigators. Moreover, dry season streamflow is forecasted at strategic points by the end of every rainy season, providing evaluation of shortage risk. Thus, water users are informed about the forecasts and corresponding restrictions well in advance, allowing for anticipated planning of irrigated areas and practices. In order to enforce restriction rules, water meters were installed in all larger water users and inefficient farmers were obligated to improve their irrigation systems’ performance. Finally, increases in irrigated area are only allowed in the case of annual crops and during months of higher water availability (November to June. The strategy differs from convectional approached based only on water use priority and has been successful in dealing with natural variability of water availability, allowing more water to be used in wet years and managing risk in an isonomic manner during dry years.

  14. TALE activators regulate gene expression in a position- and strand-dependent manner in mammalian cells.

    Uhde-Stone, Claudia; Cheung, Edna; Lu, Biao

    2014-01-24

    Transcription activator-like effectors (TALEs) are a class of transcription factors that are readily programmable to regulate gene expression. Despite their growing popularity, little is known about binding site parameters that influence TALE-mediated gene activation in mammalian cells. We demonstrate that TALE activators modulate gene expression in mammalian cells in a position- and strand-dependent manner. To study the effects of binding site location, we engineered TALEs customized to recognize specific DNA sequences located in either the promoter or the transcribed region of reporter genes. We found that TALE activators robustly activated reporter genes when their binding sites were located within the promoter region. In contrast, TALE activators inhibited the expression of reporter genes when their binding sites were located on the sense strand of the transcribed region. Notably, this repression was independent of the effector domain utilized, suggesting a simple blockage mechanism. We conclude that TALE activators in mammalian cells regulate genes in a position- and strand-dependent manner that is substantially different from gene activation by native TALEs in plants. These findings have implications for optimizing the design of custom TALEs for genetic manipulation in mammalian cells. Copyright © 2013 Elsevier Inc. All rights reserved.

  15. Biochanin a and Daidzein Influence Meiotic Maturation of Pig Oocytes in a Different Manner

    Hošková K.

    2014-09-01

    Full Text Available The aim of the study was to determine the influence of different concentrations of phytoestrogens biochanin A (BIO A; 20, 40, 50μg ml-1 and daidzein (DAI; 10, 20, 40, 50μg ml-1 on the course of meiotic maturation of pig oocytes. After a 24-hour cultivation, a stage of nuclear maturation was achieved and the areas of cumulus-oocyte complexes (COCs, as an indicator of cumulus expansion, were evaluated. The effects of both contaminants on oocytes were mani - fested from the lowest concentration used. Nuclear maturation was inhibited in a dose-dependent manner in the case of BIO A. Effects of DAI reached a plateau at a concentration of 20μg ml-1.Possible relationship to limited solubility of DAI was excluded because limits of DAI solubility in culture medium were confirmed at 50 μg ml-1.The cumulus expansion was also influenced in a different manner - reduction of the COC’s area by BIO A was dose-dependent, whereas DAI had the strongest effect on CCs in the lowest and highest concentrations used. Both phytoestrogens negatively influence the meiotic maturation of porcine oocytes but there are significant differences in their concrete effects which could relate to the diverse mechanisms of their acting on target cells.

  16. A top-down manner-based DCNN architecture for semantic image segmentation.

    Kai Qiao

    Full Text Available Given their powerful feature representation for recognition, deep convolutional neural networks (DCNNs have been driving rapid advances in high-level computer vision tasks. However, their performance in semantic image segmentation is still not satisfactory. Based on the analysis of visual mechanism, we conclude that DCNNs in a bottom-up manner are not enough, because semantic image segmentation task requires not only recognition but also visual attention capability. In the study, superpixels containing visual attention information are introduced in a top-down manner, and an extensible architecture is proposed to improve the segmentation results of current DCNN-based methods. We employ the current state-of-the-art fully convolutional network (FCN and FCN with conditional random field (DeepLab-CRF as baselines to validate our architecture. Experimental results of the PASCAL VOC segmentation task qualitatively show that coarse edges and error segmentation results are well improved. We also quantitatively obtain about 2%-3% intersection over union (IOU accuracy improvement on the PASCAL VOC 2011 and 2012 test sets.

  17. L-carnosine affects the growth of Saccharomyces cerevisiae in a metabolism-dependent manner.

    Cartwright, Stephanie P; Bill, Roslyn M; Hipkiss, Alan R

    2012-01-01

    The dipeptide L-carnosine (β-alanyl-L-histidine) has been described as enigmatic: it inhibits growth of cancer cells but delays senescence in cultured human fibroblasts and extends the lifespan of male fruit flies. In an attempt to understand these observations, the effects of L-carnosine on the model eukaryote, Saccharomyces cerevisiae, were examined on account of its unique metabolic properties; S. cerevisiae can respire aerobically, but like some tumor cells, it can also exhibit a metabolism in which aerobic respiration is down regulated. L-Carnosine exhibited both inhibitory and stimulatory effects on yeast cells, dependent upon the carbon source in the growth medium. When yeast cells were not reliant on oxidative phosphorylation for energy generation (e.g. when grown on a fermentable carbon source such as 2% glucose), 10-30 mM L-carnosine slowed growth rates in a dose-dependent manner and increased cell death by up to 17%. In contrast, in media containing a non-fermentable carbon source in which yeast are dependent on aerobic respiration (e.g. 2% glycerol), L-carnosine did not provoke cell death. This latter observation was confirmed in the respiratory yeast, Pichia pastoris. Moreover, when deletion strains in the yeast nutrient-sensing pathway were treated with L-carnosine, the cells showed resistance to its inhibitory effects. These findings suggest that L-carnosine affects cells in a metabolism-dependent manner and provide a rationale for its effects on different cell types.

  18. Engineering assessment of inactive uranium mill tailings, Grand Junction site, Grand Junction, Colorado. Phase II, Title I

    None

    1977-10-01

    Ford, Bacon and Davis Utah Inc. has performed an engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Grand Junction, Colorado. The Phase II, Title I services include the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and radiation exposures of individuals and nearby populations, the investigation of site hydrology and meteorology and the evaluation and costing of alternative corrective actions. Radon gas release from the 1.9 million tons of tailings at the Grand Junction site constitutes the most significant environmental impact, although windblown tailings and external gamma radiation are also factors. The eight alternative actions presented range from millsite decontamination (Option I), to adding various depths of stabilization cover material (Options II and III), to removal of the tailings to long-term storage sites and decontamination of the present site (Options IV through VIII). Cost estimates for the eight options range from $470,000 to $18,130,000. Reprocessing the tailings for uranium recovery does not appear to be economically attractive at present.

  19. Is it possible to give scientific solutions to Grand Challenges? On the idea of grand challenges for life science research.

    Efstathiou, Sophia

    2016-04-01

    This paper argues that challenges that are grand in scope such as "lifelong health and wellbeing", "climate action", or "food security" cannot be addressed through scientific research only. Indeed scientific research could inhibit addressing such challenges if scientific analysis constrains the multiple possible understandings of these challenges into already available scientific categories and concepts without translating between these and everyday concerns. This argument builds on work in philosophy of science and race to postulate a process through which non-scientific notions become part of science. My aim is to make this process available to scrutiny: what I call founding everyday ideas in science is both culturally and epistemologically conditioned. Founding transforms a common idea into one or more scientifically relevant ones, which can be articulated into descriptively thicker and evaluatively deflated terms and enable operationalisation and measurement. The risk of founding however is that it can invisibilise or exclude from realms of scientific scrutiny interpretations that are deemed irrelevant, uninteresting or nonsensical in the domain in question-but which may remain salient for addressing grand-in-scope challenges. The paper considers concepts of "wellbeing" in development economics versus in gerontology to illustrate this process. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Engineering assessment of inactive uranium mill tailings, Grand Junction site, Grand Junction, Colorado. Phase II, Title I

    1977-10-01

    Ford, Bacon and Davis Utah Inc. has performed an engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Grand Junction, Colorado. The Phase II, Title I services include the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and radiation exposures of individuals and nearby populations, the investigation of site hydrology and meteorology and the evaluation and costing of alternative corrective actions. Radon gas release from the 1.9 million tons of tailings at the Grand Junction site constitutes the most significant environmental impact, although windblown tailings and external gamma radiation are also factors. The eight alternative actions presented range from millsite decontamination (Option I), to adding various depths of stabilization cover material (Options II and III), to removal of the tailings to long-term storage sites and decontamination of the present site (Options IV through VIII). Cost estimates for the eight options range from $470,000 to $18,130,000. Reprocessing the tailings for uranium recovery does not appear to be economically attractive at present

  1. Canadian Environmental Assessment Act - comprehensive study report: new Grand-Mere hydroelectric facility proposed by Hydro-Quebec

    1999-06-01

    A description is given of the hydroelectric construction project as well as the environment surrounding it, the outcome of consultations with interest parties in the public, the overall environmental impacts and cumulative impacts with associated problems that may occur in carrying out the project, attempts at project and environmental mitigation, measuring the importance of the cumulative and environmental effects, conditions for project acceptance, and the overall acceptance of the project or its rejection. The older hydroelectric project was constructed in the post-1910 period and being out of date is experiencing operational problems. There are four problem areas that are important including a need for major repairs to the turbine-generators, lack of flexibility and low electrical capacity that affect the working of the sending-end substation, a state of deterioration affecting operation of the spillways concrete structure, and a bottleneck problem on the Saint-Maurice river caused by the low flow design of the Grand-Mere power station in comparison with that of the Saint-Maurice station. Considering economical, social and environmental factors, of the three options of abandoning the site, upgrading the existing site or constructing a new one, the third option is the preferred one, a conclusion based on considering the out of date state of Grand-Mere facilities and the bottleneck flow condition created on the Saint-Maurice river by the older station. Given the proposed efforts at mitigation, and the follow-up operations stated by the third option advocate, the Department of Fisheries and Oceans is of the opinion that the proposed plans will not affect the environment in an adverse manner. 7 refs

  2. SU(5)×U(1)X grand unification with minimal seesaw and Z‧-portal dark matter

    Okada, Nobuchika; Okada, Satomi; Raut, Digesh

    2018-05-01

    We propose a grand unified SU (5) × U(1)X model, where the standard SU(5) grand unified theory is supplemented by minimal seesaw and a right-handed neutrino dark matter with an introduction of a global Z2-parity. In the presence of three right-handed neutrinos (RHNs), the model is free from all gauge and mixed-gravitational anomalies. The SU(5) symmetry is broken into the Standard Model (SM) gauge group at MGUT ≃ 4 ×1016GeV in the standard manner, while the U(1)X symmetry breaking occurs at the TeV scale, which generates the TeV-scale mass of the U(1)X gauge boson (Z‧ boson) and the three Majorana RHNs. A unique Z2-odd RHN is stable and serves as the dark matter (DM) in the present Universe, while the remaining two RHNs work to generate the SM neutrino masses through the minimal seesaw. We investigate the Z‧-portal RHN DM scenario in this model context. We find that the constraints from the DM relic abundance, and the Z‧ boson search at the Large Hadron Collider (LHC), and the perturbativity bound on the U(1)X gauge coupling are complementary to narrow down the allowed parameter region in the range of 3.0 ≤mZ‧ [TeV ] ≤ 9.2 for the Z‧ boson mass. The allowed region for mZ‧ ≤ 5TeV will be fully covered by the future LHC experiments. We also briefly discuss the successful implementation of Baryogenesis and cosmological inflation scenarios in the present model.

  3. Public safety around dams : Grand River Conservation Authority

    Moore, N [Grand River Conservation Authority, Cambridge, ON (Canada)

    2009-07-01

    Ontario's Grand River Conservation Authority (GRCA) is a corporate body, through which municipalities, landowners and other organizations work cooperatively to manage the watershed and outdoor recreation. This involves reducing flood damage; improving water quality; providing adequate water supply; protecting natural areas; watershed planning; and environmental education. This presentation discussed public safety issues regarding a dam in the GRCA that is 5 minutes to downtown Brantford; 5 minutes to several elementary and secondary schools; and a popular area for anglers. The city of Brantford owns the east embankment and the Brant conservation area is located on the west embankment. The safeguards included measures to involve the municipality and local police; install better signage; install better fencing; and public education. Increasing public awareness of the dangers surrounding dams was an important point of the presentation. Results included reduced trespassing and greater community awareness. figs.

  4. Pre-cambrian geochronology in Rio Grande do Norte, Brazil

    Galindo, A.C.

    1981-08-01

    The Precambrian region polyciclic caracter, in the Rio Grande do Norte State has make difficulties to its geochronological and geological studies. Four importants tectonometamorphic occurences identified dissimulate the original isotopic composition of the rocks. Is much defined the presence of three geochronological events wich left vestiges in the differents Serido litological units. The first event is related with Jequie cicle (2,7 b.y) and related with the Caico Group rocks. The second important event define the Transamazonic cicle (2.1 b.y). The third is correlated with Brazilian Cicle, when occurred the granitoids and pegmatites bodies formation. This third event was the last in this region and affect the other units too. (C.D.G.) [pt

  5. Gauge hierarchy in an SO(10) supersymmetric grand unified model

    Zhiyong, Z.

    1982-01-01

    An SO(10) supersymmetric grand unified model is constructed in which the gauge hierarchy problem may be solved. Using Higgs superfields belonging to the SO(10) representations 16, 10 and 54, it is found that if SO(10) is broken down to SU(3)sub(c)xSU(2)sub(L)xU(1) via SO(6)xSO(4)approximately equal to SU(4)sub(c)xSU(2)sub(L)xSU(2)sub(R) at unification mass scales without supersymmetry breaking, the gauge hierarchy puzzle might be carried away. It is also shown that the colour-triplet Higgs, which mediates proton decay, is superheavy by an incredibly accurate, but 'natural' adjustment of parameters in the potential. (author)

  6. The Dialogical Traveler: A Reading of Semprun's Le grand voyage

    Sally M. Silk

    1990-06-01

    Full Text Available In light of discourse theory influenced by Bakhtin's concept of dialogism, the notion of voice has changed significantly so that we are invited to read discourse in a way that represents a departure from Bakhtin. The theories of François Flahault, Michel Pêchetut, and John Frow, who inquire into the importance of conditions of production of language, are used to explore the vain search for a subject-centered voice in Jorge Semprun's Le Grand voyage . The narrating subject Gerard experiences "homelessness" in discourse because he fails to find a voice of his own. His relationship to music and literature depends on an other; in invasion of self by the other occurs so that Gerard speaks only through alien voices that confront him throughout the narrative. In discourse a decentering occurs that is not present at the thematic level: the protagonist arrives at a destination, but discourse does not.

  7. Leucemia de grandes linfócitos granulares

    Terra,Bruno; Maia,Amanda M.

    2010-01-01

    O presente estudo tem como objetivo o estabelecimento de fundamentação teórica atualizada baseada em revisão bibliográfica sobre a leucemia de grandes linfócitos granulares (LGLG), doença onco-hematológica, que, devido à sua relativa raridade, é pouco conhecida e subdiagnosticada. A LGLG é caracterizada pela proliferação clonal de linfócitos T ou NK na medula óssea e/ou no sangue periférico. Dentre as manifestações clínico-laboratoriais, podem ocorrer citopenias (anemia e/ou neutropenia e/ou ...

  8. Reconciling grand unification with strings by anisotropic compactifications

    Dundee, Ben; Raby, Stuart; Wingerter, Akin

    2008-01-01

    We analyze gauge coupling unification in the context of heterotic strings on anisotropic orbifolds. This construction is very much analogous to effective five-dimensional orbifold grand unified theory field theories. Our analysis assumes three fundamental scales: the string scale M S , a compactification scale M C , and a mass scale for some of the vectorlike exotics M EX ; the other exotics are assumed to get mass at M S . In the particular models analyzed, we show that gauge coupling unification is not possible with M EX =M C , and in fact we require M EX C ∼3x10 16 GeV. We find that about 10% of the parameter space has a proton lifetime (from dimension six gauge exchange) 10 33 yr 0 e + ) 36 yr. The other 80% of the parameter space gives proton lifetimes below Super-Kamiokande bounds. The next generation of proton decay experiments should be sensitive to the remaining parameter space.

  9. Prevalence of canine parvovirus infection in Grand Tunis, Tunisia

    Ghada Tagorti

    2018-03-01

    Results: The overall prevalence of CPV-2 was 32.14% (n=54/168. A total number of 54 young dogs, aging 1 to 7 months, of American Staffordshire terrier, German shepherd, Rottweiler and Spaniel breeds were affected. There was no sex predisposition and German shepherd was the over-represented breed (n=33/54; 61.11%. The prevalence of clinical cases below the three months old was 70.37% (n=38/54 with autumn (n=27/54; 50% as the most common season of infection. Furthermore, the study showed that 87.04% (n=47/54 of CPV-2 unvaccinated young dogs were positive. Conclusion: This work was a new descriptive study concerning canine parvovirus infection in the Grand Tunis; further studies are required to better characterize the epidemiology of CPV-2 infection in Tunisia. [J Adv Vet Anim Res 2018; 5(1.000: 93-97

  10. Big Bologna. Le anomalie degli spazi pubblici in grande scala

    Richard Ingersoll

    2013-06-01

    Full Text Available Nella periferia di Bologna sono nati recentemente nuovi spazi pubblici, molto diversi rispetto a quelli della città storica, che esprimono chiaramente  la mania della grandezza, la sindrome di Big Bologna. Ovunque si getta lo sguardo si notano nuove manifestazioni di una scala fuori proporzione che contribuisce alla segregazione sociale. Da quando sono arrivate le torri bianche della megastruttura di Kenzo Tange alla Fiera, la grande scala ha dato origine a spazi pubblici poco ameni per la vita urbana. Forse questi megaprogetti sono inevitabili segni dell’epoca della globalizzazione, ma ci si chiede se i committenti e i loro architetti sono stati consapevoli di quanto la progettazione di tali forme causa un deterrente alla socializzazione.

  11. Brasil – Estados Unidos: grandes expectativas, pequenos atritos

    Virgílio Caixeta Arraes

    2016-12-01

    Full Text Available O princípio da administração de Barack Obama, do Partido Democrata, gerou expectativa positiva na América Latina, região desdenhada pelo antecessor, George Bush, do Partido Republicano. Valorizar o continente seria prestigiar o Brasil. Todavia, o relacionamento não foi o esperado, embora sem grandes decepções também. The beginning of Barack Obama´s term produced positive expectations on Latin America, a continent which was ignored by his predecessor, George Bush. To give attention to Latin America implies giving prestige to Brazil.  Nonetheless the real relationship could not meet the expectations, although without causing great deceptions.

  12. O turning point da grande reportagem multimídia

    Longhi, Raquel Ritter; Universidade Federal de Santa Catarina / Campus Reitor João David Ferreira Lima. Florianópolis, Santa Catarina. Brasil. CEP: 88049-900 Tel: (48) 3721.9000

    2015-01-01

    Este artigo analisa o estado da arte da grande reportagem multimídia no jornalismo online, atentando para um momento que se pode definir como “turning point”, ou ponto de virada desse tipo de formato noticioso. A partir de uma sistematização da evolução dos formatos expressivos multimidiáticos da notícia no jornalismo digital, o artigo identifica três momentos principais dessa trajetória: o slide-show noticioso, no início dos anos 2000; os especiais multimídia, de meados de 2000 a 2011 e a gr...

  13. Squark and slepton mass relations in grand unified theories

    Cheng, H.; Hall, L.J.

    1995-01-01

    In the minimal supersymmetric standard model, assuming universal scalar masses at large energies, there are four intragenerational relations between the masses of the squarks and sleptons for each light generation. In this paper we study the scalar mass relations which follow only from the assumption that at large energies there is a grand unified theory which leads to a significant prediction of the weak mixing angle. Two new intragenerational mass relations for each of the light generations are derived. In addition, a third mass relation is found which relates the Higgs boson masses, the masses of the third generation scalars, and the masses of the scalars of the lighter generations. Verification of a fourth mass relation, involving only the charged slepton masses, provides a signal for SO(10) unification

  14. Grande Ronde Basin Fish Habitat Enhancement Project : 2007 Annual Report.

    McGowan, Vance R.; Morton, Winston H.

    2008-12-30

    On July 1, 1984 the Bonneville Power Administration and the Oregon Department of Fish and Wildlife entered into an intergovernmental contract to initiate fish habitat enhancement work in the Joseph Creek subbasin of the Grande Ronde River Basin in northeast Oregon. In 1985 the Upper and Middle Grande Ronde River, and Catherine Creek subbasins were included in the contract, and in 1996 the Wallowa River subbasin was added. The primary goal of 'The Grande Ronde Basin Fish Habitat Enhancement Project' is to create, protect, and restore riparian and instream habitat for anadromous salmonids, thereby maximizing opportunities for natural fish production within the basin. This project provided for implementation of Program Measure 703 (C)(1), Action Item 4.2 of the Northwest Power Planning Council's Columbia River Basin Fish and Wildlife Program (NPPC, 1987), and continues to be implemented as offsite mitigation for mainstem fishery losses caused by the Columbia River hydro-electric system. All work conducted by the Oregon Department of Fish and Wildlife and partners is on private lands and therefore requires that considerable time be spent developing rapport with landowners to gain acceptance of, and continued cooperation with this program throughout 10-15 year lease periods. Both passive and active restoration treatment techniques are used. Passive regeneration of habitat, using riparian exclosure fencing and alternate water sources are the primary method to restore degraded streams when restoration can be achieved primarily through changes in management. Active restoration techniques using plantings, bioengineering, site-specific instream structures, or whole stream channel alterations are utilized when streams are more severely degraded and not likely to recover in a reasonable timeframe. Individual projects contribute to and complement ecosystem and basin-wide watershed restoration efforts that are underway by state, federal, and tribal agencies, and

  15. Engineering grand challenges and the attributes of the global engineer

    Guerra, Aida; Ulseth, Ron; Jonhson, Bart

    2017-01-01

    Technology has been changing world in ways never imagined. The ever-evolving society and rapid development posed different demands and challenges to the engineering profession. Addressing these challenges means to re-vision and reform the ways we educate future engineers and the attributes need...... to be enhanced. This paper reports a literature review with aim to (1) understand the different stakeholders’ perspectives, namely students, educators, and employers, (2) understand the profile of the global engineer (i.e. knowledge, competences and skills), and (3) outline and discuss learning strategies....... As a result, the paper presents the main gaps in the existing knowledge, formulates research hypothesis, and proposes a research design for a follow up empirical study to investigate further the engineering grand challenges, the attributes needed to solve them, and the learning environments required....

  16. The Grand Ethiopian Renaissance Dam: Source of cooperation or contention?

    Teferi Taye, Meron; Tadesse, Tsegaye; Senay, Gabriel; Block, Paul

    2016-01-01

    This paper discusses the challenges and benefits of the Grand Ethiopian Renaissance Dam (GERD), which is under construction and expected to be operational on the Blue Nile River in Ethiopia in a few years. Like many large-scale projects on transboundary rivers, the GERD has been criticized for potentially jeopardizing downstream water security and livelihoods through upstream unilateral decision making. In spite of the contentious nature of the project, the authors argue that this project can provide substantial benefits for regional development. The GERD, like any major river infrastructure project, will undeniably bring about social, environmental, and economic change, and in this unique case has, on balance, the potential to achieve success on all fronts. It must be stressed, however, that strong partnerships between riparian countries are essential. National success is contingent on regional cooperation.

  17. Grand unification and the fundamental problems of classical cosmology

    Turner, M.S.

    1981-01-01

    The accomplishments of classical cosmology are reviewed. In particular, the hot big bang model provides a reliable framework for understanding the evolution of the universe back to times at least as early as approx. 0.01 s after the big bang. At present there are (at least) six fundamental problems which have not yet been (completely) resolved. They are: (1) the origin of the baryon number-to-entropy ratio, (2) the origin of the isotropy, (3) the origin of the homogeneity and inhomogeneity, (4) the origin of the flatness, (5) the cosmological constant, and (6) the monopole problem. The role that grand unification has played, and may play in the resolution of these puzzles is discussed. Guth's inflationary universe, which addresses five of these six problems, is reviewed

  18. Pattern of neutrino mixing in grand unified theories

    Milton, K.; Tanaka, K.

    1981-01-01

    It was found previously in SO(10) grand unified theories that if the neutrinos have a Dirac mass and a right-handed Majorana mass (approx. 10 15 GeV) but no left-handed Majorana mass, there is small ν/sub e/ mixing but ν/sub μ/ - ν/sub tau/ mixing can be substantial. This problem is reexamined on the basis of a formalism that assumes that the up, down, lepton, and neutrino mass matrices arise from a single complex 10 and a single 126 Higgs boson. This formalism determines the Majorana mass matrix in terms of quark mass matrices. Adopting three different sets of quark mass matrices that produce acceptable fermion mass ratios and Cabbibo mixing produces results consistent with the above; however, in the optimum case, ν/sub e/ - ν/sub μ/ mixing can be of the order of the Cabbibo angle

  19. STEM education for teachers in the Rio Grande Valley

    Ries, Judit Gyorgyey; Baguio, Margaret R.

    2015-11-01

    We have worked with elementary and middle school teachers in the Rio Grande Valley for the last 10 years bringing Earth and Space Science themed workshops to underserved areas of Texas. The Texas curriculum was also changed to include Astronomy and Space Science requirement in the tests students need to take to prove their academic preparedness. The teachers worked through a variety of inquiry-based, hands-on activities after a short presentation on the background science. In order to evaluate our effectiveness, we have asked the teachers to take pre- and post-workshop tests, and we asked them to fill out a self-reflective survey. We will report on our experiences, what works best with the teachers, and in what areas we still have a long way to go.This work was supported by various NASA education grants and Cooperative agreements, as well as grants provided by the Texas Space Grant Consortium.

  20. Potentiation Effects of Half-Squats Performed in a Ballistic or Nonballistic Manner.

    Suchomel, Timothy J; Sato, Kimitake; DeWeese, Brad H; Ebben, William P; Stone, Michael H

    2016-06-01

    This study examined and compared the acute effects of ballistic and nonballistic concentric-only half-squats (COHSs) on squat jump performance. Fifteen resistance-trained men performed a squat jump 2 minutes after a control protocol or 2 COHSs at 90% of their 1 repetition maximum (1RM) COHS performed in a ballistic or nonballistic manner. Jump height (JH), peak power (PP), and allometrically scaled peak power (PPa) were compared using three 3 × 2 repeated-measures analyses of variance. Statistically significant condition × time interaction effects existed for JH (p = 0.037), PP (p = 0.041), and PPa (p = 0.031). Post hoc analysis revealed that the ballistic condition produced statistically greater JH (p = 0.017 and p = 0.036), PP (p = 0.031 and p = 0.026), and PPa (p = 0.024 and p = 0.023) than the control and nonballistic conditions, respectively. Small effect sizes for JH, PP, and PPa existed during the ballistic condition (d = 0.28-0.44), whereas trivial effect sizes existed during the control (d = 0.0-0.18) and nonballistic (d = 0.0-0.17) conditions. Large statistically significant relationships existed between the JH potentiation response and the subject's relative back squat 1RM (r = 0.520; p = 0.047) and relative COHS 1RM (r = 0.569; p = 0.027) during the ballistic condition. In addition, large statistically significant relationship existed between JH potentiation response and the subject's relative back squat strength (r = 0.633; p = 0.011), whereas the moderate relationship with the subject's relative COHS strength trended toward significance (r = 0.483; p = 0.068). Ballistic COHS produced superior potentiation effects compared with COHS performed in a nonballistic manner. Relative strength may contribute to the elicited potentiation response after ballistic and nonballistic COHS.

  1. Intermittent Hypoxia Disrupts Glucose Homeostasis in Liver Cells in an Insulin-Dependent and Independent Manner

    Chen Juan Gu

    2018-05-01

    Full Text Available Background/Aims: Obstructive sleep apnea is associated with diabetes and insulin resistance, but the underlying mechanisms remain unclear. The purpose of the current study was to determine the molecular effects of intermittent hypoxia (IH on hepatic insulin signaling and glucose homeostasis, and whether c-Jun NH2-terminal-kinase (JNK contributed to metabolic responses to IH in liver cells. Methods: The human HepG2 cells and rat FAO cells were exposed to 10, 30, 120, 240 or 360 cycles of IH (1% O2 for 60 s followed by 21% O2 for 60s, 7.5 cycles per hour or normoxia as a control. In a subgroup, we exposed cells to 360 cycles of IH with the JNK inhibitor SP600125. After IH exposure, cell glycogen content and glucose output were measured using colorimetric assay kits. Canonical insulin signaling and gluconeogenic genes were measured by western blot and quantitative polymerase chain reaction. Results: IH decreased insulin-stimulated protein kinase B (AKT/glycogen synthase kinase-3β (GSK-3β phosphorylation in a time-dependent manner, while inhibiting forkhead box protein O1 (FOXO1 expression and phosphoenolpyruvate carboxykinase (PEPCK transcription independent of insulin signaling. JNK inhibitor SP600125 partially restored AKT/ GSK-3β phosphorylation and glycogen synthesis, but did not affect other IH-induced glucose metabolic changes. Conclusion: IH in vitro impaired insulin signal transduction in liver cells as assessed by inhibited AKT/GSK-3β phosphorylation via JNK activation. IH inhibited FOXO1 and gluconeogenesis in an insulin-independent manner.

  2. L-carnosine affects the growth of Saccharomyces cerevisiae in a metabolism-dependent manner.

    Stephanie P Cartwright

    Full Text Available The dipeptide L-carnosine (β-alanyl-L-histidine has been described as enigmatic: it inhibits growth of cancer cells but delays senescence in cultured human fibroblasts and extends the lifespan of male fruit flies. In an attempt to understand these observations, the effects of L-carnosine on the model eukaryote, Saccharomyces cerevisiae, were examined on account of its unique metabolic properties; S. cerevisiae can respire aerobically, but like some tumor cells, it can also exhibit a metabolism in which aerobic respiration is down regulated. L-Carnosine exhibited both inhibitory and stimulatory effects on yeast cells, dependent upon the carbon source in the growth medium. When yeast cells were not reliant on oxidative phosphorylation for energy generation (e.g. when grown on a fermentable carbon source such as 2% glucose, 10-30 mM L-carnosine slowed growth rates in a dose-dependent manner and increased cell death by up to 17%. In contrast, in media containing a non-fermentable carbon source in which yeast are dependent on aerobic respiration (e.g. 2% glycerol, L-carnosine did not provoke cell death. This latter observation was confirmed in the respiratory yeast, Pichia pastoris. Moreover, when deletion strains in the yeast nutrient-sensing pathway were treated with L-carnosine, the cells showed resistance to its inhibitory effects. These findings suggest that L-carnosine affects cells in a metabolism-dependent manner and provide a rationale for its effects on different cell types.

  3. Investigation of organic matter migrating from polymeric pipes into drinking water under different flow manners.

    Zhang, Ling; Liu, Shuming; Liu, Wenjun

    2014-02-01

    Polymeric pipes, such as unplasticized polyvinyl chloride (uPVC) pipes, polypropylene random (PPR) pipes and polyethylene (PE) pipes are increasingly used for drinking water distribution lines. Plastic pipes may include some additives like metallic stabilizers and other antioxidants for the protection of the material during its production and use. Thus, some compounds can be released from those plastic pipes and cast a shadow on drinking water quality. This work develops a new procedure to investigate three types of polymer pipes (uPVC, PE and PPR) with respect to the migration of total organic carbon (TOC) into drinking water. The migration test was carried out in stagnant conditions with two types of migration processes, a continuous migration process and a successive migration process. These two types of migration processes are specially designed to mimic the conditions of different flow manners in drinking water pipelines, i.e., the situation of continuous stagnation with long hydraulic retention times and normal flow status with regular water renewing in drinking water networks. The experimental results showed that TOC release differed significantly with different plastic materials and under different flow manners. The order of materials with respect to the total amount of TOC migrating into drinking water was observed as PE > PPR > uPVC under both successive and continuous migration conditions. A higher amount of organic migration from PE and PPR pipes was likely to occur due to more organic antioxidants being used in pipe production. The results from the successive migration tests indicated the trend of the migration intensity of different pipe materials over time, while the results obtained from the continuous migration tests implied that under long stagnant conditions, the drinking water quality could deteriorate quickly with the consistent migration of organic compounds and the dramatic consumption of chlorine to a very low level. Higher amounts of TOC

  4. A Library in the Grands Moulins de Paris: challenging Reality

    Catherine Tresson

    2006-07-01

    Full Text Available In 2006, the University of Paris 7 and its new Main Library will move to Paris Rive Gauche, a recently developed neighbourhood on the left bank of the Seine. The library will occupy most of the city’s former industrial mills, the Grands Moulins de Paris. As part of the project, the library developed a very detailed functional program. The facilities are expected to comprise 1,800 workstations (half of which will be computerized, and upon completion will have a capacity of 300,000 freely accessible documents and 350,000 documents in store over a total surface area of some 12,000 m2. The architect Rudy Ricciotti won the international competition to design the library held in 2001. Perfectly suited to its function, the industrial building in which the library is housed dates from the 1920s. It presents both advantages (vast surfaces, sufficient load-bearing capacity, natural light, etc. and obstacles (restrictions on free circulation, forests of columns in certain areas, interrupted spaces, etc. to being transformed into a library that is functional and adapted to its purposes. The building’s structure and the constraints it imposed profoundly influenced the program which had to be adjusted, and also affected other aspects, including the arrangement and features of the furnishings as well as the building’s system of signs. In agreement with the university, the library worked in close collaboration with the architect from the earliest sketches onwards. As a result, his initial plan also evolved considerably. The installation of the library in the Grands Moulins offers us a chance to observe the nature and effects of the interactions between the transformation of a building and the evolution of a program.

  5. RESCUE OF Cucurbita spp. GERMPLASM IN RIO GRANDE DO NORTE

    GRACE KELLY LEITE DE LIMA

    2016-01-01

    Full Text Available Com objetivo de resgatar germoplasma de Cucurbita spp. da agricultura familiar do estado do Rio Grande do Norte, quantificar a variabilidade fenotípica e identificar as principais espécies cultivadas, foram organizadas 17 expedições para coleta de acessos, nos municípios de Baraúna, Rio do Fogo e Touros (principais fornecedores de frutos para o comercio estadual e de mais oito municípios de diferentes microrregiões do Estado (Apodi, Caraúbas, Ceará Mirim, Cerro Corá, Currais Novos, João Câmara, Lagoa Nova e Macaíba. Cada acesso coletado foi composto por um fruto ou aproximadamente vinte sementes fornecidas pelo próprio agricultor. Todos os acessos foram identificados quanto à espécie botânica e realizados os procedimentos de acondicionamento, identificação e armazenamento das sementes em câmara fria para preservação do material. Uma amostra dos acessos coletados como frutos e uma pequena parte dos acessos obtidos como sementes da espécie C. moschata foram multiplicados usando-se autofecundação das plantas. Plantas e frutos foram caracterizados preliminarmente com auxílio de descritores morfológicos. Resgatou-se acessos em todos os municípios visitados, sendo 112 de C. moschata e 50 de C. maxima. Verificou-se predominância do cultivo da espécie C. moschata bem como constatou-se grande variabilidade para vários descritores de planta e fruto nos acessos que foram caracterizados.

  6. QUALIDADE AMBIENTAL DO RESERVATÓRIO CAJÁ, TABOLEIRO GRANDE (RN

    Francisco Ericardo do Nascimento

    2016-07-01

    Full Text Available O reservatório Cajá é o manancial responsável por abastecer a cidade de Taboleiro Grande mas, atualmente, sofre com alguns problemas relacionados ao uso e ocupação do entorno, além da diminuição do volume em função da baixa precipitação pluviométrica na região do Alto Oeste Potiguar. O objetivo deste trabalho foi realizar uma análise da qualidade ambiental do reservatório Cajá, localizado no município de Taboleiro Grande (RN. A metodologia de abordagem consistiu em leitura de parâmetros de qualidade de água com aparelho multiparâmetro, levantamento pontuais de impactos ambientais, e entrevistas com a população local sobre questões relacionadas ao uso e qualidade das águas do reservatório, tendo como principal foco a percepção ambiental dos munícipes. Os parâmetros utilizados para analisar a qualidade das águas foram: Temperatura, pH, Oxigênio Dissolvido e Condutividade Elétrica. Estabeleceram-se dois pontos no reservatório, onde as leituras foram realizadas em dois períodos sazonais, isto é, na estação seca e chuvosa. O resultado das análises mostrou que o OD e CE não apresentaram os índices estabelecidos pelo CONAMA 357/2005 para o consumo da água para o ser humano. Foram identificadas também algumas fontes que contribuem para a degradação da qualidade da água do manancial

  7. Stratigraphy of the Grande Savane Ignimbrite Sequence, Dominica, Lesser Antilles

    Schneider, S.; Smith, A. L.; Deuerling, K.; Killingsworth, N.; Daly, G.

    2007-12-01

    The island of Dominica, located in the central part of the Lesser Antilles island arc has eight potentially active volcanoes. One of these, Morne Diablotins, is a composite stratovolcano with several superimposed stratigraphic sequences ranging in age from Pliocene (4-2 Ma) to "Younger" Pleistocene (22,000 and >40,000 years B.P. The ignimbrite sequences form four flow fans that reached both the east and west coasts of the island. One of these flow fans, the Grande Savane, on the west coast of the island, also extends off-shore for a distance of at least 14 km as a distinctive submarine fan. Stratigraphical studies of the on- shore deposits that make up this fan indicate an older sequence of block and ash flow deposits, within which occurs a distinctive vulcanian fall deposit. These are overlain, with no evidence of an intervening paleosol, by a sequence of ignimbrites containing welded horizons (ranging in thickness from around 4 m to 16m). The lack of fall deposits beneath the ignimbrites suggest they may have been formed by instantaneous continuous collapse of the eruption column. This whole succession is overlain by a series of planar and dune bedded pumiceous surge deposits with interbedded pumiceous lapilli fall and ash fall deposits, that extend laterally outside of the main area of ignimbrite deposition. Beds within this upper sequence often contain accretionary lapilli and gas cavities suggesting magma-water interaction. The youngest deposits from Morne Diablotins appear to be valley- fill deposits of both ignimbrite and block and ash flow. A comparison of the of the Grande Savane pyroclastic sequence with the Pointe Ronde (west coast) and Londonderry (east coast) pyroclastic flow fans will provide information on the eruptive history of this major Plinian episode.

  8. Fatores associados ao atraso no desenvolvimento em crianças, Rio Grande, Rio Grande do Sul, Brasil Factores asociados con retraso en el desarrollo de los niños, Rio Grande, Rio Grande do Sul, Brasil Factors associated with delay in development in children, Rio Grande, Rio Grande do Sul, Brazil

    Aline Alves Veleda

    2011-03-01

    Full Text Available Estudo analítico com o objetivo de avaliar os fatores associados ao atraso no desenvolvimento em crianças entre 8 a 12 meses de idade indicadas como de risco ao nascer no município do Rio Grande, Rio Grande do Sul, Brasil. Foram utilizados como instrumentos o Teste de Triagem de Desenvolvimento de Denver II (TTDD II, a avaliação antropométrica e questionários estruturados. Participaram 220 crianças consideradas de risco ou não ao nascer. Foi encontrada uma prevalência de 20,5% de suspeita de atraso no desenvolvimento neuropsicomotor. As crianças que apresentaram risco de um TTDD II suspeito faziam parte de famílias de mais baixa renda; eram filhos de mães que haviam realizado menos de seis consultas de pré-natal e apresentavam índice peso-idade inadequado. Os dados sugerem a necessidade de um replanejamento das políticas de saúde infantil, visto que outros critérios poderiam ser incluídos nas condições de risco para a criança ao nascer.Estudio analítico con el objetivo de evaluar los factores asociados al atraso en el desarrollo en niños de 8 a 12 meses de edad indicados como riesgo al nacer en el municipio de Rio Grande, RS, Brasil. Fueron utilizadas como herramientas la Prueba de Tamizaje del Desarrollo de Denver II, la evaluación antropométrica y cuestionarios estructurados. Participaron 220 niños considerados de riesgo o no al nacer. Fue encontrada una prevalencia del 20,5% de sospecha de atraso en el desarrollo neuropsicomotor. Los niños que presentaron riesgo de un DDST II sospechoso formaban parte de familias de más baja renta; eran hijos de madres que habían realizado menos de seis consultas de prenatal y presentaban índice peso-edad inadecuado. Los datos sugieren la necesidad de un replanteamiento de las políticas de salud infantil, así como otros criterios podrían ser inclusos en las condiciones de riesgo para el niño al nacer.This analytical study aims to evaluate the factors associated to

  9. 78 FR 60994 - Culturally Significant Objects Imported for Exhibition Determinations: “In Grand Style...

    2013-10-02

    ... Determinations: ``In Grand Style: Celebrations in Korean Art During the Joseon Dynasty'' SUMMARY: Notice is... objects to be included in the exhibition ``In Grand Style: Celebrations in Korean Art during the Joseon Dynasty,'' imported from abroad for temporary exhibition within the United States, are of cultural...

  10. 75 FR 10308 - Fire Management Plan, Final Environmental Impact Statement, Record of Decision, Grand Canyon...

    2010-03-05

    ... DEPARTMENT OF THE INTERIOR National Park Service Fire Management Plan, Final Environmental Impact... Statement for the Fire Management Plan, Grand Canyon National Park. SUMMARY: Pursuant to the National... the Record of Decision for the Fire Management Plan, Grand Canyon National Park, Arizona. On January...

  11. First-Year Students' Attitudes towards the Grand Challenges and Nanotechnology

    Lakin, Joni M.; Han, Yi; Davis, Edward

    2016-01-01

    The "Grand Challenges" for Engineering are an effort to portray engineering as a field that has profound impacts on society. This study explores the level of interest first-year engineering students had in various "Grand Challenges" and in nanotechnology topics. We administered a survey to a large sample of students enrolled in…

  12. Upper Rio Grande water operations model: A tool for enhanced system management

    Gail Stockton; D. Michael Roark

    1999-01-01

    The Upper Rio Grande Water Operations Model (URGWOM) under development through a multi-agency effort has demonstrated capability to represent the physical river/reservoir system, to track and account for Rio Grande flows and imported San Juan flows, and to forecast flows at various points in the system. Testing of the Rio Chama portion of the water operations model was...

  13. Necessity of intermediate mass scales in grand unified theories with spontaneously broken CP invariance

    Senjanovic, G.

    1982-07-01

    It is demonstrated that the spontaneous breakdown of CP invariance in grand unified theories requires the presence of intermediate mass scales. The simplest realization is provided by weakly broken left-right symmetry in the context of SU(2)sub(L) x SU(2)sub(R) x U(1)sub(B-L) model embedded in grand unified theories. (author)

  14. Exórdio para o estudo da pedagogia libertária em Rio Grande

    Vargas, Francisco Furtado Gomes Riet

    2007-01-01

    Aborda a História da Pedagogia Libertária e suas implicações práticas com ênfase ao Estado do Rio Grande do Sul, no Brasil. It approaches the History of Libertarian Pedagogy and its practical implications with emphasis to the State of Rio Grande do Sul, in Brazil.

  15. Spatial and seasonal variations of the contamination within water body of the Grand Canal, China

    Wang, X.L.; Han, Jingyi; Xu, L.G.; Zhang, Q.

    2010-01-01

    To delineate the character of contaminations in the Grand Canal, China, a three-year study (2004-2006) was conducted to investigate variations the water quality in the canal. Results showed that the variation of water quality within the Grand Canal was of there is remarkable spatial and seasonal

  16. 76 FR 6517 - San Luis & Rio Grande Railroad-Petition for a Declaratory Order

    2011-02-04

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35380] San Luis & Rio... petition filed by San Luis & Rio Grande Railroad (SLRG), the Board instituted a declaratory order... proposed operation of a truck-to-rail transload facility in Antonito, Colorado. See San Luis & Rio Grande R...

  17. Maurice Denis dans la Grande Guerre Maurice Denis in the Great War

    Fabienne Stahl

    2012-03-01

    Full Text Available Maurice Denis (1870-1943 did not participate actively in the First World War, but this period inevitably brought a break in his life and in his work. Although he was found medically unfit to serve on the front line, the patriotic élan he felt led him to become involved in the war effort: he was mobilised as a railway guard in Conches (Eure and was subsequently attached to the military administration in Evreux in 1914-1915; drawings and paintings bear witness to this confused and unsettled period for the artist. Despite having home leave for the birth of his sixth child, he remained committed to the war effort. In October 1917, he undertook a mission as an army painter; noting the devastation caused by war in several (unpublished sketchbooks, showing a detailed and poignant vision of ruined bridges, castles, churches, etc.. When Victory was finally achieved, he devoted himself to the task of commemoration.

  18. Grand Narrative Pemberantasan Korupsi dalam Wacana Konflik Sepak Bola di Media Cetak

    Afdal Makkuraga Putra

    2017-05-01

    Full Text Available Eradication of corruption has been a grand narrative since the early of reformation era. Mass media became part of the preservation of the grand narrative. Grand narrative is the main narration which becomes basis and universal character since it can be used as standard to measure and assess other narratives. This study analyzes grand narrative of corruption eradication in Indonesia soccer conflict in print media by using critical discourse by Norman Fairclough as research method. The result shows that media preserved grand narrative of corruption eradication through image projection of corruptors as common enemy. The spread of anti-corruption information through mass media carried out continuously and sustainably is a manifestation of the commitment to fight corruption. Information provided by media does not only explains the state’s loss but up to the development of its completion.

  19. O serviço social em indústrias de grande porte do Rio Grande do Sul = Social work in big companies in Rio Grande do Sul

    Ziliotto, Denise Macedo

    2010-01-01

    Full Text Available A temática deste artigo centra-se na prática profissional do assistente social na área empresarial, especialmente em indústrias de grande porte. Pretende contribuir na explicitação da especificidade do exercício profissional do Serviço Social nas organizações, entendido como uma atividade inserida na divisão sociotécnica do trabalho e sendo perpassada pelas transformações que estão ocorrendo no mundo laboral nas últimas décadas. A pesquisa foi realizada com profissionais atuantes no contexto investigado através de entrevistas pessoais, avaliadas pela análise de conteúdo. Os resultados obtidos sugerem a atuação predominante de mulheres com formação em universidades privadas, com trajetória profissional majoritária no setor empresarial. Os processos desenvolvidos pelas entrevistadas buscam reverter a imagem assistencialista do campo, valorizando as relações no trabalho e a sinergia com a organização como um todo. A importância do conhecimento multidisciplinar como instrumento para as intervenções e do posicionamento crítico diante das demandas que lhe são dirigidas na dinâmica organizacional foram evidenciados na pesquisa. O caráter recente e ainda restrito da presença dos profissionais no segmento industrial sinaliza um processo de inserção e reconhecimento ainda em construção

  20. Plato’s Republic to Rivers’Five Spot: Poets Among Painters De la République de Platon au « Five Spot » à Manhattan : des poètes chez les peintres

    Eamonn Wall

    2007-01-01

    Full Text Available Dans cet article, Eamonn Wall considère les œuvres de divers artistes et penseurs de l’âge classique à l’époque actuelle, et tente de décrire les diverses méthodologies choisies par les écrivains et leurs commentateurs pour écrire des poèmes et les interpréter. Il sera principalement question ici des poètes de l’École de New York qui, apparue dans les années 1950, comprenait parmi ses membres des poètes tels que John Ashbery, Frank O’ Hara, James Schuyler, Kenneth Koch, et bien d’autres encore. Ce mouvement poétique empruntait son nom au groupe de peintres qui occupa la scène new yorkaise après la Deuxième Guerre mondiale. Eamonn Wall s’arrête sur différents points de convergence et de dissonance entre les poètes et les peintres de ces Écoles, avant de considérer les liens entre poésie et arts visuels dans l’Irlande et la Grande-Bretagne tant contemporaines qu’anciennes afin de montrer les échecs et les réussites des poètes qui essayèrent de faire de la poésie à partir des arts visuels. Il conclut que pour un poète, un tableau est toujours un sujet irrésistible et se montre certain que tant qu’il y aura des œuvres aux murs des musées, il y aura des poètes pour les mettre en poésie.

  1. Diagnóstico da floricultura no Rio Grande do Sul Diagnosis of floriculture in Rio Grande do Sul, Brazil

    Atelene Normann Kämpf

    1999-09-01

    Full Text Available O objetivo deste trabalho foi avaliar o segmento da produção de flores e plantas ornamentais no Rio Grande do Sul, Brasil, por meio de um levantamento a campo. O estudo faz parte de um projeto global, apoiado pelo Instituto Brasileiro de Floricultura (IBRAFLOR e pelo Ministério da Agricultura e do Abastecimento (MAARA, através do Departamento Nacional de Cooperativismo (DENACOOP. Com base nos formulários preenchidos nas propriedades, foi elaborado um cadastro dos floricultores, com seus endereços e produções. A floricultura gaúcha conta com 257 produtores, que cultivam o total de 304ha em 65 municípios; 30% dessa área é ocupada com flores de corte, 33% com mudas para jardim, 29% com outros produtos da floricultura e 8% com plantas envasadas. O sistema de cultivo predominante é a céu aberto (89%, com baixos investimentos tecnológicos.A survey was conducted to quantify flower and ornamental plant production in the State of Rio Grande do Sul State, Brazil. The Brazilian Floriculture Institute (IBRAFLOR and the Agriculture Ministry (MAARA - DENACOOP granted this research. Based on an inventory formulary a catalog including the nurseries, addresses and main crops was elaborated. There are 257 growers in this State with an area of 304ha distributed among 65 counties; 30% of this area are cultivated with cut flowers, 33% with annuals and perennials for garden, 29% with other floriculture products and 8% with potted plants. The main system of cultivation is not protected with low technological investments.

  2. Habitual Chocolate Consumption May Increase Body Weight in a Dose-Response Manner

    Greenberg, James A.; Buijsse, Brian

    2013-01-01

    Objective Habitual chocolate intake was recently found to be associated with lower body weight in three cross-sectional epidemiological studies. Our objective was to assess whether these cross-sectional results hold up in a more rigorous prospective analysis. Methods We used data from the Atherosclerosis Risk in Communities cohort. Usual dietary intake was assessed by questionnaire at baseline (1987–98), and after six years. Participants reported usual chocolate intake as the frequency of eating a 1-oz (∼28 g) serving. Body weight and height were measured at the two visits. Missing data were replaced by multiple imputation. Linear mixed-effects models were used to evaluate cross-sectional and prospective associations between chocolate intake and adiposity. Results Data were from 15,732 and 12,830 participants at the first and second visit, respectively. More frequent chocolate consumption was associated with a significantly greater prospective weight gain over time, in a dose-response manner. For instance, compared to participants who ate a chocolate serving less often than monthly, those who ate it 1–4 times a month and at least weekly experienced an increase in Body Mass Index (kg/m2) of 0.26 (95% CI 0.08, 0.44) and 0.39 (0.23, 0.55), respectively, during the six-year study period. In cross-sectional analyses the frequency of chocolate consumption was inversely associated with body weight. This inverse association was attenuated after excluding participants with preexisting obesity-related illness. Compared to participants without such illness, those with it had higher BMI and reported less frequent chocolate intake, lower caloric intake, and diets richer in fruits and vegetables. They tended to make these dietary changes after becoming ill. Conclusions Our prospective analysis found that a chocolate habit was associated with long-term weight gain, in a dose-response manner. Our cross-sectional finding that chocolate intake was associated with lower body

  3. Habitual chocolate consumption may increase body weight in a dose-response manner.

    Greenberg, James A; Buijsse, Brian

    2013-01-01

    Habitual chocolate intake was recently found to be associated with lower body weight in three cross-sectional epidemiological studies. Our objective was to assess whether these cross-sectional results hold up in a more rigorous prospective analysis. We used data from the Atherosclerosis Risk in Communities cohort. Usual dietary intake was assessed by questionnaire at baseline (1987-98), and after six years. Participants reported usual chocolate intake as the frequency of eating a 1-oz (~28 g) serving. Body weight and height were measured at the two visits. Missing data were replaced by multiple imputation. Linear mixed-effects models were used to evaluate cross-sectional and prospective associations between chocolate intake and adiposity. Data were from 15,732 and 12,830 participants at the first and second visit, respectively. More frequent chocolate consumption was associated with a significantly greater prospective weight gain over time, in a dose-response manner. For instance, compared to participants who ate a chocolate serving less often than monthly, those who ate it 1-4 times a month and at least weekly experienced an increase in Body Mass Index (kg/m2) of 0.26 (95% CI 0.08, 0.44) and 0.39 (0.23, 0.55), respectively, during the six-year study period. In cross-sectional analyses the frequency of chocolate consumption was inversely associated with body weight. This inverse association was attenuated after excluding participants with preexisting obesity-related illness. Compared to participants without such illness, those with it had higher BMI and reported less frequent chocolate intake, lower caloric intake, and diets richer in fruits and vegetables. They tended to make these dietary changes after becoming ill. Our prospective analysis found that a chocolate habit was associated with long-term weight gain, in a dose-response manner. Our cross-sectional finding that chocolate intake was associated with lower body weight did not apply to participants without

  4. Habitual chocolate consumption may increase body weight in a dose-response manner.

    James A Greenberg

    Full Text Available OBJECTIVE: Habitual chocolate intake was recently found to be associated with lower body weight in three cross-sectional epidemiological studies. Our objective was to assess whether these cross-sectional results hold up in a more rigorous prospective analysis. METHODS: We used data from the Atherosclerosis Risk in Communities cohort. Usual dietary intake was assessed by questionnaire at baseline (1987-98, and after six years. Participants reported usual chocolate intake as the frequency of eating a 1-oz (~28 g serving. Body weight and height were measured at the two visits. Missing data were replaced by multiple imputation. Linear mixed-effects models were used to evaluate cross-sectional and prospective associations between chocolate intake and adiposity. RESULTS: Data were from 15,732 and 12,830 participants at the first and second visit, respectively. More frequent chocolate consumption was associated with a significantly greater prospective weight gain over time, in a dose-response manner. For instance, compared to participants who ate a chocolate serving less often than monthly, those who ate it 1-4 times a month and at least weekly experienced an increase in Body Mass Index (kg/m2 of 0.26 (95% CI 0.08, 0.44 and 0.39 (0.23, 0.55, respectively, during the six-year study period. In cross-sectional analyses the frequency of chocolate consumption was inversely associated with body weight. This inverse association was attenuated after excluding participants with preexisting obesity-related illness. Compared to participants without such illness, those with it had higher BMI and reported less frequent chocolate intake, lower caloric intake, and diets richer in fruits and vegetables. They tended to make these dietary changes after becoming ill. CONCLUSIONS: Our prospective analysis found that a chocolate habit was associated with long-term weight gain, in a dose-response manner. Our cross-sectional finding that chocolate intake was associated with

  5. The canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner

    Yano, Fumiko; Kugimiya, Fumitaka; Ohba, Shinsuke; Ikeda, Toshiyuki; Chikuda, Hirotaka; Ogasawara, Toru; Ogata, Naoshi; Takato, Tsuyoshi; Nakamura, Kozo; Kawaguchi, Hiroshi; Chung, Ung-il

    2005-01-01

    To better understand the role of the canonical Wnt signaling pathway in cartilage development, we adenovirally expressed a constitutively active (Canada) or a dominant negative (dn) form of lymphoid enhancer factor-1 (LEF-1), the main nuclear effector of the pathway, in undifferentiated mesenchymal cells, chondrogenic cells, and primary chondrocytes, and examined the expression of markers for chondrogenic differentiation and hypertrophy. caLEF-1 and LiCl, an activator of the canonical pathway, promoted both chondrogenic differentiation and hypertrophy, whereas dnLEF-1 and the gene silencing of β-catenin suppressed LiCl-promoted effects. To investigate whether these effects were dependent on Sox9, a master regulator of cartilage development, we stimulated Sox9-deficient ES cells with the pathway. caLEF-1 and LiCl promoted both chondrogenic differentiation and hypertrophy in wild-type, but not in Sox9-deficient, cells. The response of Sox9-deficient cells was restored by the adenoviral expression of Sox9. Thus, the canonical Wnt signaling pathway promotes chondrocyte differentiation in a Sox9-dependent manner

  6. Stat3 signaling regulates embryonic stem cell fate in a dose-dependent manner

    Chih-I Tai

    2014-09-01

    Full Text Available Stat3 is essential for mouse embryonic stem cell (mESC self-renewal mediated by LIF/gp130 receptor signaling. Current understanding of Stat3-mediated ESC self-renewal mechanisms is very limited, and has heretofore been dominated by the view that Stat3 signaling functions in a binary “on/off” manner. Here, in contrast to this binary viewpoint, we demonstrate a contextual, rheostat-like mechanism for Stat3's function in mESCs. Activation and expression levels determine whether Stat3 functions in a self-renewal or a differentiation role in mESCs. We also show that Stat3 induces rapid differentiation of mESCs toward the trophectoderm (TE lineage when its activation level exceeds certain thresholds. Stat3 induces this differentiation phenotype via induction of Tfap2c and its downstream target Cdx2. Our findings provide a novel concept in the realm of Stat3, self-renewal signaling, and pluripotent stem cell biology. Ultimately, this finding may facilitate the development of conditions for the establishment of authentic non-rodent ESCs.

  7. The H3K27 demethylase, Utx, regulates adipogenesis in a differentiation stage-dependent manner.

    Kazushige Ota

    Full Text Available Understanding the molecular mechanisms that drive adipogenesis is important in developing new treatments for obesity and diabetes. Epigenetic regulations determine the capacity of adipogenesis. In this study, we examined the role of a histone H3 lysine 27 demethylase, the ubiquitously transcribed tetratricopeptide repeat protein on the X chromosome (Utx, in the differentiation of mouse embryonic stem cells (mESCs to adipocytes. Using gene trapping, we examined Utx-deficient male mESCs to determine whether loss of Utx would enhance or inhibit the differentiation of mESCs to adipocytes. Utx-deficient mESCs showed diminished potential to differentiate to adipocytes compared to that of controls. In contrast, Utx-deficient preadipocytes showed enhanced differentiation to adipocytes. Microarray analyses indicated that the β-catenin/c-Myc signaling pathway was differentially regulated in Utx-deficient cells during adipocyte differentiation. Therefore, our data suggest that Utx governs adipogenesis by regulating c-Myc in a differentiation stage-specific manner and that targeting the Utx signaling pathway could be beneficial for the treatment of obesity, diabetes, and congenital utx-deficiency disorders.

  8. The Probiotic Lactobacillus Prevents Citrobacter rodentium-Induced Murine Colitis in a TLR2-Dependent Manner.

    Ryu, Seung-Hyun; Park, Jong-Hyung; Choi, Soo-Young; Jeon, Hee-Yeon; Park, Jin-Il; Kim, Jun-Young; Ham, Seung-Hoon; Choi, Yang-Kyu

    2016-07-28

    The main objective of this study was to investigate whether Lactobacillus rhamnosus GG (LGG) ameliorated the effects of Citrobactor rodentium infection in Toll-like receptor 2 (TLR2) knockout (KO) and TLR4 KO mice, as well as in wild-type C57BL/6 (B6) mice. TLR2 KO, TLR4 KO, and B6 mice were divided into three groups per each strain. Each group had an uninfected control group (n = 5), C. rodentium-infected group (n = 8), and LGG-pretreated C. rodentium-infected group (n = 8). The survival rate of B6 mice infected with C. rodentium was higher when pretreated with LGG. Pretreatment with LGG ameliorated C. rodentium-induced mucosal hyperplasia in B6 and TLR4 KO mice. However, in C-rodentium-infected TLR2 KO mice, mucosal hyperplasia persisted, regardless of pretreatment with LGG. In addition, LGG-pretreated B6 and TLR4 KO mice showed a decrease in spleen weight and downregulation of tumor necrosis factor alpha, interferon gamma, and monocyte chemotactic protein 1 mRNA expression compared with the non-pretreated group. In contrast, such changes were not observed in TLR2 KO mice, regardless of pretreatment with LGG. From the above results, we conclude that pretreatment with LGG ameliorates C. rodentium-induced colitis in B6 and TLR4 KO mice, but not in TLR2 KO mice. Therefore, LGG protects mice from C. rodentium-induced colitis in a TLR2-dependent manner.

  9. The aPKC-CBP Pathway Regulates Adult Hippocampal Neurogenesis in an Age-Dependent Manner

    Ayden Gouveia

    2016-10-01

    Full Text Available While epigenetic modifications have emerged as attractive substrates to integrate environmental changes into the determination of cell identity and function, specific signals that directly activate these epigenetic modifications remain unknown. Here, we examine the role of atypical protein kinase C (aPKC-mediated Ser436 phosphorylation of CBP, a histone acetyltransferase, in adult hippocampal neurogenesis and memory. Using a knockin mouse strain (CbpS436A in which the aPKC-CBP pathway is deficient, we observe impaired hippocampal neuronal differentiation, maturation, and memory and diminished binding of CBP to CREB in 6-month-old CbpS436A mice, but not at 3 months of age. Importantly, elevation of CREB activity rescues these deficits, and CREB activity is reduced whereas aPKC activity is increased in the murine hippocampus as they age from 3 to 6 months regardless of genotype. Thus, the aPKC-CBP pathway is a homeostatic compensatory mechanism that modulates hippocampal neurogenesis and memory in an age-dependent manner in response to reduced CREB activity.

  10. Fesselin is a target protein for calmodulin in a calcium-dependent manner

    KoIakowski, Janusz; Wrzosek, Antoni; Dabrowska, Renata

    2004-01-01

    Fesselin is a basic protein isolated from smooth muscle which binds G-actin and accelerates its polymerization as well as cross-links assembled filaments [J. Muscle Res. Cell Motil. 20 (1999) 539; Biochemistry 40 (2001) 14252]. In this report experimental evidence is provided for the first time proving that fesselin can interact with calmodulin in a Ca 2+ -dependent manner in vitro. Using ion exchange, followed by calmodulin-affinity chromatography, enabled us to simplify and shorten the fesselin preparation procedure and increase its yield by about three times in comparison to the procedure described by Leinweber et al. [J. Muscle Res. Cell Motil. 20 (1999) 539]. Fesselin interaction with dansyl-labelled calmodulin causes a 2-fold increase in maximum fluorescence intensity of the fluorophore and a 21 nm blue shift of the spectrum. The transition of complex formation between fesselin and calmodulin occurs at submicromolar concentration of calcium ions. The dissociation constant of fesselin Ca 2+ /calmodulin complexes amounted to 10 -8 M. The results suggest the existence of a direct link between Ca 2+ /calmodulin and fesselin at the level of actin cytoskeleton dynamics in smooth muscle

  11. TGF-β's delay skeletal muscle progenitor cell differentiation in an isoform-independent manner

    Schabort, Elske J.; Merwe, Mathilde van der; Loos, Benjamin; Moore, Frances P.; Niesler, Carola U.

    2009-01-01

    Satellite cells are a quiescent heterogenous population of mononuclear stem and progenitor cells which, once activated, differentiate into myotubes and facilitate skeletal muscle repair or growth. The Transforming Growth Factor-β (TGF-β) superfamily members are elevated post-injury and their importance in the regulation of myogenesis and wound healing has been demonstrated both in vitro and in vivo. Most studies suggest a negative role for TGF-β on satellite cell differentiation. However, none have compared the effect of these three isoforms on myogenesis in vitro. This is despite known isoform-specific effects of TGF-β1, -β2 and -β3 on wound repair in other tissues. In the current study we compared the effect of TGF-β1, -β2 and -β3 on proliferation and differentiation of the C2C12 myoblast cell-line. We found that, irrespective of the isoform, TGF-β increased proliferation of C2C12 cells by changing the cellular localisation of PCNA to promote cell division and prevent cell cycle exit. Concomitantly, TGF-β1, -β2 and -β3 delayed myogenic commitment by increasing MyoD degradation and decreasing myogenin expression. Terminal differentiation, as measured by a decrease in myosin heavy chain (MHC) expression, was also delayed. These results demonstrate that TGF-β promotes proliferation and delays differentiation of C2C12 myoblasts in an isoform-independent manner

  12. Comprehending non-native speakers: theory and evidence for adjustment in manner of processing.

    Lev-Ari, Shiri

    2014-01-01

    Non-native speakers have lower linguistic competence than native speakers, which renders their language less reliable in conveying their intentions. We suggest that expectations of lower competence lead listeners to adapt their manner of processing when they listen to non-native speakers. We propose that listeners use cognitive resources to adjust by increasing their reliance on top-down processes and extracting less information from the language of the non-native speaker. An eye-tracking study supports our proposal by showing that when following instructions by a non-native speaker, listeners make more contextually-induced interpretations. Those with relatively high working memory also increase their reliance on context to anticipate the speaker's upcoming reference, and are less likely to notice lexical errors in the non-native speech, indicating that they take less information from the speaker's language. These results contribute to our understanding of the flexibility in language processing and have implications for interactions between native and non-native speakers.

  13. Bilirubin Modulates Acetylcholine Receptors In Rat Superior Cervical Ganglionic Neurons In a Bidirectional Manner

    Zhang, Chengmi; Wang, Zhenmeng; Dong, Jing; Pan, Ruirui; Qiu, Haibo; Zhang, Jinmin; Zhang, Peng; Zheng, Jijian; Yu, Weifeng

    2014-01-01

    Autonomic dysfunction as a partial contributing factor to cardiovascular instability in jaundiced patients is often associated with increased serum bilirubin levels. Whether increased serum bilirubin levels could directly inhibit sympathetic ganglion transmission by blocking neuronal nicotinic acetylcholine receptors (nAChRs) remains to be elucidated. Conventional patch-clamp recordings were used to study the effect of bilirubin on nAChRs currents from enzymatically dissociated rat superior cervical ganglia (SCG) neurons. The results showed that low concnetrations (0.5 and 2 μM) of bilirubin enhanced the peak ACh-evoked currents, while high concentrations (3 to 5.5 µM) of bilirubin suppressed the currents with an IC50 of 4 ± 0.5 μM. In addition, bilirubin decreased the extent of desensitization of nAChRs in a concentration-dependent manner. This inhibitory effect of bilirubin on nAChRs channel currents was non-competitive and voltage independent. Bilirubin partly improved the inhibitory effect of forskolin on ACh-induced currents without affecting the action of H-89. These data suggest that the dual effects of enhancement and suppression of bilirubin on nAChR function may be ascribed to the action mechanism of positive allosteric modulation and direct blockade. Thus, suppression of sympathetic ganglionic transmission through postganglionic nAChRs inhibition may partially contribute to the adverse cardiovascular effects in jaundiced patients. PMID:25503810

  14. MCP-1 expressed by osteoclasts stimulates osteoclastogenesis in an autocrine/paracrine manner

    Miyamoto, Kana; Ninomiya, Ken; Sonoda, Koh-Hei; Miyauchi, Yoshiteru; Hoshi, Hiroko; Iwasaki, Ryotaro; Miyamoto, Hiroya

    2009-01-01

    Monocyte chemoattractant protein-1 (MCP-1) is a chemokine that plays a critical role in the recruitment and activation of leukocytes. Here, we describe that multinuclear osteoclast formation was significantly inhibited in cells derived from MCP-1-deficient mice. MCP-1 has been implicated in the regulation of osteoclast cell-cell fusion; however defects of multinuclear osteoclast formation in the cells from mice deficient in DC-STAMP, a seven transmembrane receptor essential for osteoclast cell-cell fusion, was not rescued by recombinant MCP-1. The lack of MCP-1 in osteoclasts resulted in a down-regulation of DC-STAMP, NFATc1, and cathepsin K, all of which were highly expressed in normal osteoclasts, suggesting that osteoclast differentiation was inhibited in MCP-1-deficient cells. MCP-1 alone did not induce osteoclastogenesis, however, the inhibition of osteoclastogenesis in MCP-1-deficient cells was restored by addition of recombinant MCP-1, indicating that osteoclastogenesis was regulated in an autocrine/paracrine manner by MCP-1 under the stimulation of RANKL in osteoclasts.

  15. Paternal engagement during childbirth depending on the manner of their preparation.

    Sioma-Markowska, Urszula; Poręba, Ryszard; Machura, Mariola; Skrzypulec-Plinta, Violetta

    2016-01-01

    The analysis of the forms of paternal activity depending on the manner of their preparation, including stages of labor. A prospective survey-based study involved 250 fathers who participated in their child's birth. The fathers included in the study were present during all stages of family-assisted natural labor. The study was conducted one day after childbirth with the use of a survey prepared by the authors. Statistical calculations were conducted using the Statistica PL software. The frequency of individual qualitative features (non-measurable) was assessed by means of a non-parametric χ² (chi-squared) test. The statistical significance level was p fathers included in the study (52.4%) participated in childbirth with no prior preparation. The dominant form of preparation involved self-education from books, magazines and the Internet (24%). 23.6% of fathers participated in ante-natal classes. The study demonstrated that fathers prepared for childbirth in ante-natal classes more often engaged in the supportive role, provided nursing care and carried out instrumental monitoring during each stage of childbirth. The fathers prepared for childbirth in ante-natal classes more often engage in the supportive role, provide nursing care and carry out instrumental control during each stage of childbirth. Ante-natal classes should be promoted as an optimal form of preparation for active participation in childbirth. Moreover, other forms of paternal ante-natal education as well as continued education in a delivery room should be developed.

  16. Unacknowledged threats proffered "in a manner of speaking": recognizing workplace bullying as shaming.

    Dzurec, Laura Cox; Kennison, Monica; Albataineh, Raya

    2014-07-01

    The purpose of this study was to examine workplace bullying victims' perceptions of what they heard their bully counterparts say through their use of prosody. From a sampling frame of 89 manuscripts referenced in the authors' previous studies, we identified a subset (n = 10) that included quotes regarding bullying victims' perceptions of communication experiences with their bully perpetrators. We used hermeneutics and a recursive metasynthesis to interpret quotes embedded in the manuscripts chosen for this study. Two-thirds of language is expressed nonverbally through prosody or "manner of speaking"-rhythm, stress, intonation, and vocabulary choice. We found that as bullies communicated with their intended victims over time, they used prosody across subtle, linked communications, or boldly and openly in public venues, to establish a context-embedded, one-way communication process of "doublespeak." Bullies' confusing prosodic communication processes served to recontexualize victims' situations and, through mechanisms largely unacknowledged by the victims, to subtly demean their personhood, and to shame them and render them voiceless. This study directs formal attention to the language of workplace bullying. Further study might strengthen opportunities to effectively address and curtail the long-term personal, professional, and organizational injuries deriving from workplace bullying. © 2014 Sigma Theta Tau International.

  17. Nuclear size is sensitive to NTF2 protein levels in a manner dependent on Ran binding

    Vuković, Lidija D.; Jevtić, Predrag; Zhang, Zhaojie; Stohr, Bradley A.; Levy, Daniel L.

    2016-01-01

    ABSTRACT Altered nuclear size is associated with many cancers, and determining whether cancer-associated changes in nuclear size contribute to carcinogenesis necessitates an understanding of mechanisms of nuclear size regulation. Although nuclear import rates generally positively correlate with nuclear size, NTF2 levels negatively affect nuclear size, despite the role of NTF2 (also known as NUTF2) in nuclear recycling of the import factor Ran. We show that binding of Ran to NTF2 is required for NTF2 to inhibit nuclear expansion and import of large cargo molecules in Xenopus laevis egg and embryo extracts, consistent with our observation that NTF2 reduces the diameter of the nuclear pore complex (NPC) in a Ran-binding-dependent manner. Furthermore, we demonstrate that ectopic NTF2 expression in Xenopus embryos and mammalian tissue culture cells alters nuclear size. Finally, we show that increases in nuclear size during melanoma progression correlate with reduced NTF2 expression, and increasing NTF2 levels in melanoma cells is sufficient to reduce nuclear size. These results show a conserved capacity for NTF2 to impact on nuclear size, and we propose that NTF2 might be a new cancer biomarker. PMID:26823604

  18. Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner

    Simon Lecoutre

    2017-08-01

    Conclusions: Consistent with the DOHaD hypothesis, persistent epigenetic remodeling occurs at regulatory regions especially within intergenic sequences, linked to higher leptin gene expression in adult HF offspring in a depot-specific manner.

  19. Report: EPA Needs Policies and Procedures to Manage Public Pesticide Petitions in a Transparent and Efficient Manner

    Report #16-P-0019, October 27, 2015. OPP’s lack of policies and procedures to manage public pesticide petitions in a transparent and efficient manner can result in unreasonable delay lawsuits costing the agency time and resources.

  20. Particle physics models of inflation in supergravity and grand unification

    Kostka, Philipp Manuel

    2010-01-01

    In the first part of this thesis, we study classes of hybrid and chaotic inflation models in four-dimensional N=1 supergravity. Therein, the η-problem can be resolved relying on fundamental symmetries in the Kaehler potential. Concretely, we investigate explicit realizations of superpotentials, in which the flatness of the inflaton potential is protected at tree level by a shift symmetry or a Heisenberg symmetry in the Kaehler potential. In the latter case, the associated modulus field can be stabilized during inflation by supergravity effects. In the context of hybrid inflation, a novel class of models, to which we refer as ''tribrid inflation,'' turns out to be particularly compatible with such symmetry solutions to the η-problem. Radiative corrections due to operators in the superpotential, which break the respective symmetry, generate the required small slope of the inflaton potential. Additional effective operators in the Kaehler potential can reduce the predicted spectral index so that it agrees with latest observational data. Within a model of chaotic inflation in supergravity with a quadratic potential, we apply the Heisenberg symmetry to allow for viable inflation with super-Planckian field values, while the associated modulus is stabilized. We show that radiative corrections are negligible in this context. In the second part, the tribrid inflation models are extended to realize gauge non-singlet inflation. This is applied to the matter sector of supersymmetric Grand Unified Theories based on the Pati-Salam gauge group. For the specific scenario in which the right-handed sneutrino is the inflaton, we study the scalar potential in a D-flat valley. We show that despite potentially dangerous two-loop corrections, the required flatness of the potential can be maintained. The reason for this is the strong suppression of gauge interactions of the inflaton field due to its symmetry breaking vacuum expectation value. In addition, the production of stable

  1. Did a slump source cause the 1929 Grand Banks tsunami?

    Løvholt, F.; Schulten, I.; Mosher, D.; Harbitz, C. B.; Krastel, S.

    2017-12-01

    On November 18, 1929, a Mw 7.2 earthquake occurred beneath the upper Laurentian Fan, south of Newfoundland. The earthquake displaced about 100 km3 of sediment volume that rapidly evolved into a turbidity current revealed by a series of successive telecommunication cable breaks. A tsunami with fatal consequences along the south coast of Newfoundland also resulted. This tsunami is attributed to sediment mass failure as no seafloor displacement due to the earthquake is observed or expected. Although sidescan sonar, sub-bottom profiler and modern multibeam data show surficial sediment slumping and translational slide activity in the upper part of the slope, no major headscarp, single evacuation area or large mass transport deposit are observed. Sediment mass failure has been interpreted as broadly distributed and shallow, likely occurring in a retrogressive fashion. The question remained, therefore, as to how such complex failure kinematics could generate a tsunami. The Grand Banks tsunami is the only landslide tsunami for which traces are found at transoceanic distances. Despite being a landmark event, only a couple of attempts to model the tsunami exist. None of these have been able to match tsunami observations. Recently acquired seismic reflection data suggest that rotational slumping of a thick sediment mass ( 500 m) on the St. Pierre Slope may have occurred, causing seafloor displacements (fault traces) up to 100 m in height. The previously mapped surficial failures were a consequence of slumping of the thicker mass. Here, we simulate tsunami generation using the new geophysical information to construct different tsunamigenic slump sources. In addition, we undertake simulations assuming a flowing surficial landslide. The numerical simulations shows that its large and rapid vertical displacements render the slump source more tsunamigenic than the alternative surficial landslide. The simulations using the slump source roughly complies with observations of large run

  2. Particle physics models of inflation in supergravity and grand unification

    Kostka, Philipp Manuel

    2010-12-03

    In the first part of this thesis, we study classes of hybrid and chaotic inflation models in four-dimensional N=1 supergravity. Therein, the {eta}-problem can be resolved relying on fundamental symmetries in the Kaehler potential. Concretely, we investigate explicit realizations of superpotentials, in which the flatness of the inflaton potential is protected at tree level by a shift symmetry or a Heisenberg symmetry in the Kaehler potential. In the latter case, the associated modulus field can be stabilized during inflation by supergravity effects. In the context of hybrid inflation, a novel class of models, to which we refer as ''tribrid inflation,'' turns out to be particularly compatible with such symmetry solutions to the {eta}-problem. Radiative corrections due to operators in the superpotential, which break the respective symmetry, generate the required small slope of the inflaton potential. Additional effective operators in the Kaehler potential can reduce the predicted spectral index so that it agrees with latest observational data. Within a model of chaotic inflation in supergravity with a quadratic potential, we apply the Heisenberg symmetry to allow for viable inflation with super-Planckian field values, while the associated modulus is stabilized. We show that radiative corrections are negligible in this context. In the second part, the tribrid inflation models are extended to realize gauge non-singlet inflation. This is applied to the matter sector of supersymmetric Grand Unified Theories based on the Pati-Salam gauge group. For the specific scenario in which the right-handed sneutrino is the inflaton, we study the scalar potential in a D-flat valley. We show that despite potentially dangerous two-loop corrections, the required flatness of the potential can be maintained. The reason for this is the strong suppression of gauge interactions of the inflaton field due to its symmetry breaking vacuum expectation value. In addition, the

  3. Estimating large complex projects Estimando proyectos grandes y complejos

    Cliff Schexnayder

    2007-08-01

    Full Text Available Managing large capital construction projects requires the coordination of a multitude of human, organizational, technical, and natural resources. Quite often, the engineering and construction complexities of such projects are overshadowed by economic, societal, and political challenges. The ramifications and effects, which result from differences between early project cost estimates and the bid price or the final project cost, are significant. Over the time span between the initiation of a project and the completion of construction many factors influence a project's final costs. This time span is normally several years in duration but for highly complex and technologically challenging projects, project duration can easily exceed a decade. Over that period, changes to the project scope often occur. The subject here is a presentation of strategies that support realistic cost estimating. Through literature review and interviews with transportation agencies in the U.S. and internationally the authors developed a database of the factors that are the root causes of cost estimation problemsGestionar proyectos de construcción de grandes capitales requiere de la coordinación de una multitud de recursos humanos, organizacionales, técnicos y naturales. Frecuentemente, las complejidades del diseño y construcción de esos grandes proyectos son tapadas por sus desafíos económicos, políticos y sociales. Las ramificaciones y efectos que resultan de las diferencias entre la estimación de costo inicial, el costo de la propuesta adjudicada y el costo final del proyecto son significativas. Hay numerosos factores que inciden en el costo final del proyecto entre su inicio y finalización. La duración es generalmente de varios años y puede incluso superar la década para aquellos especialmente complejos y desafiantes. En ese período de tiempo, cambios en los alcances del proyecto cambian frecuentemente. El tópico del presente artículo es mostrar

  4. REESTRUTURAÇÃO PRODUTIVA NO RIO GRANDE DO NORTE

    Francisco Fransualdo de Azevedo

    2013-01-01

    Full Text Available El objetivo de este articulo es analizar el proceso de reestruturación produtiva del sistema capitalista, discu- tiendo sus distintas dimensiones, concretamente la económica, social, política y técnica. Se trata, por tanto, de explicar como este proceso se à desarrollando em el territorio de Rio Grande do Norte (Brasil, teniendo em cuenta las vuejas y nuevas materialidades que constituyen este proceso de producción del espacio durante las últimas décadas. Al mismo tiempo que lo ayudan a explicar. Desde el punto de vista metodológico, se hace una breve revisión teórica y conceptual acerca de la recolección de datos y la sistematización y ana- lisi de los datos procedentes de fuentes oficiales. Como son las secretarias y los organos gubernamentales -Instituto Brasileiro de Geografia e Estatística, Instituto de Desenvolvimento Sustentável e Meio Ambiente do Rio Grande do Norte, Agência Nacional de Petróleo, Serviço Brasileiro de Apoio às Micro e Pequenas Empresas- y también algunas instituciones académicas, como es el caso del Observatório das Metrópoles. De todo ello parece desprenderse que los años 1980/90 estuvieron marcados por cambios importantes em el proceso de producción del espacio potiguar, destacando em particular los que estuvieron asociados a los incentivos estatales, em consonancia con acciones e intenciones del capítal privado interessado em el fo- mento de la reeestructuración de las actividades em todo el arco de la estructura económica: las actividades agropeciarias, la pesca, y la carcinicultura, así como el turismo, la extracción minera, la construcción de infrestructuras públicas, la industria textil, el comercio y los servicios.

  5. Descriptive summary of the Grande Ronde Basalt type section, Columbia River Basalt Group

    Camp, V.E.; Price, S.M.; Reidel, S.P.

    1978-10-01

    The Grande Ronde Basalt type section, located in extreme southeastern Washington, was measured, sampled, and characterized. The section is 800 meters thick and is comprised of 35 Grande Ronde Basalt flows. These flows are divisible into 3 magnetostratiographic units termed, in ascending order, the R 1 , the N 1 , and the R 2 . The R 1 unit is represented by 13 reversely polarized flows; the N 1 unit, by 13 normally polarized flows; and the R 2 , by 9 reversely polarized flows. Chemically, the Grande Ronde Basalt flows are divided into 2 major groups, termed A and B. The compositions of the lower 9 flows, members of Group A, are similar to either the high-Mg Grande Ronde chemical type, the high-Ti Grande Ronde chemical type, or the Pomona chemical type. The compositions of the upper 25 flows, members of Group B, are predominantly similar to the low-Mg Grande Ronde chemical type. Petrographically, the Grande Ronde Basalt flows are generally fine grained and aphyric, and have a intergranular or intersertal micro-texture. Major mineral phases include plagioclase (An/sub 40-60/) and augite; minor mineral phases include pigeonite, orthopyroxene, ilmenite, titanomagnetite, and olivine. Group A flows generally contain more olivine and less pigeonite than do Group B flows. 6 figures, 6 tables

  6. Populating a Control Point Database: A cooperative effort between the USGS, Grand Canyon Monitoring and Research Center and the Grand Canyon Youth Organization

    Brown, K. M.; Fritzinger, C.; Wharton, E.

    2004-12-01

    The Grand Canyon Monitoring and Research Center measures the effects of Glen Canyon Dam operations on the resources along the Colorado River from Glen Canyon Dam to Lake Mead in support of the Grand Canyon Adaptive Management Program. Control points are integral for geo-referencing the myriad of data collected in the Grand Canyon including aerial photography, topographic and bathymetric data used for classification and change-detection analysis of physical, biologic and cultural resources. The survey department has compiled a list of 870 control points installed by various organizations needing to establish a consistent reference for data collected at field sites along the 240 mile stretch of Colorado River in the Grand Canyon. This list is the foundation for the Control Point Database established primarily for researchers, to locate control points and independently geo-reference collected field data. The database has the potential to be a valuable mapping tool for assisting researchers to easily locate a control point and reduce the occurrance of unknowingly installing new control points within close proximity of an existing control point. The database is missing photographs and accurate site description information. Current site descriptions do not accurately define the location of the point but refer to the project that used the point, or some other interesting fact associated with the point. The Grand Canyon Monitoring and Research Center (GCMRC) resolved this problem by turning the data collection effort into an educational exercise for the participants of the Grand Canyon Youth organization. Grand Canyon Youth is a non-profit organization providing experiential education for middle and high school aged youth. GCMRC and the Grand Canyon Youth formed a partnership where GCMRC provided the logistical support, equipment, and training to conduct the field work, and the Grand Canyon Youth provided the time and personnel to complete the field work. Two data

  7. Histoplasmose pulmonar aguda no Rio Grande do Sul Acute pulmonary histoplasmosis in the State of Rio Grande do Sul, Brazil

    Gisela Unis

    2005-02-01

    Full Text Available INTRODUÇÃO: A histoplasmose pulmonar aguda depende da inalação de uma grande quantidade de propágulos fúngicos por um paciente hígido. O tempo de exposição determina a gravidade da doença. Uma epidemia é influenciada por fatores que afetam o crescimento e a transmissão do Histoplasma capsulatum var. capsulatum na natureza. OBJETIVO: Identificar os aspectos epidemiológicos e clínico-laboratoriais dos pacientes com histoplasmose pulmonar aguda no Rio Grande do Sul e compará-los com as microepidemias relatadas no Brasil. MÉTODO: Foram revisados 212 prontuários clínicos de pacientes com histoplasmose dos arquivos do Laboratório de Micologia do Complexo Hospitalar Santa Casa de Porto Alegre (RS num período de 25 anos (1977-2002. Foram identificados e incluídos no estudo os casos de histoplasmose pulmonar aguda com cultivo positivo e/ou achado histopatológico compatível. As microepidemias foram diagnosticadas com a comprovação de um caso ou evidência soromicológica com história clínica compatível. Foram revisadas as microepidemias publicadas no Brasil. RESULTADOS: Dezoito de um total de 212 pacientes (8,5% foram incluídos no trabalho. A idade variou de 8 a 63 anos (média de 35,4; mediana de 34,5, e 67% eram do sexo masculino. A história epidemiológica foi sugestiva em 11 pacientes (61%. O tipo primário de histoplasmose pulmonar aguda foi o mais freqüente (17; 95%. Houve predomínio de casos isolados. CONCLUSÃO: O reconhecimento de casos isolados e a presença de microepidemias demonstram a abundância do H. capsulatum no solo, e juntamente com a ocorrência de todas as formas da doença, confirmam o Rio Grande do Sul como hiperendêmico para histoplasmose.BACKGROUND: Acute pulmonary histoplasmosis is a respiratory infection occurring when an otherwise healthy individual inhales a large quantity of fungal propagules. Length of exposure determines disease severity. An epidemic is influenced by factors affecting the

  8. Analysis of the mass media coverage of the Gates Foundation grand challenges in global health initiative.

    Verma, G

    2009-03-01

    The Grand Challenges were launched in 2003 by the Gates Foundation and other collaborators to address the health needs of developing countries. This paper outlines the current problem with health research and development in the context of inequality as conveyed by the 90/10 divide. The paper then looks at the focus and nature of press reporting of global health issues by analysing how press articles have portrayed the Grand Challenges in Global Health initiative. Analysis of the mass media illustrates that the focus of reporting on the Grand Challenges tends to be on utilitarian themes, leaving issues related to justice and equity comparatively under-reported.

  9. Grand challenge problems in environmental modeling and remediation: Groundwater contaminant transport. Final project report 1998

    1998-04-01

    The over-reaching goal of the Groundwater Grand Challenge component of the Partnership in Computational Science (PICS) was to develop and establish the massively parallel approach for the description of groundwater flow and transport and to address the problem of uncertainties in the data and its interpretation. This necessitated the development of innovative algorithms and the implementation of massively parallel computational tools to provide a suite of simulators for groundwater flow and transport in heterogeneous media. This report summarizes the activities and deliverables of the Groundwater Grand Challenge project funded through the High Performance Computing grand challenge program of the Department of Energy from 1995 through 1997

  10. A Nurse-Led Innovation in Education: Implementing a Collaborative Multidisciplinary Grand Rounds.

    Matamoros, Lisa; Cook, Michelle

    2017-08-01

    Multidisciplinary grand rounds provides an opportunity to promote excellence in patient care through scholarly presentations and interdisciplinary collaboration with an innovative approach. In addition, multidisciplinary grand rounds serves to recognize expertise of staff, mentor and support professional development, and provide a collaborative environment across all clinical disciplines and support services. This article describes a process model developed by nurse educators for implementing a multidisciplinary grand rounds program. The components of the process model include topic submissions, coaching presenters, presentations, evaluations, and spreading the work. This model can be easily implemented at any organization. J Contin Educ Nurs. 2017;48(8):353-357. Copyright 2017, SLACK Incorporated.

  11. Terracina - terra di briganti, tappa prediletta dai (grand- turisti

    Clemens Arts

    2012-05-01

    Full Text Available Terracina: bandit territory and resort cherished by (grand- touristsFor travellers who left the Eternal City, Terracina was one of the first stages, and almost an obligatory one, on their way to Naples and further south. The charming fishing town on the Tyrrhenian Sea situated on the Via Appia offered to those who had crossed the boring and bothersome Pontine Marshes a glimpse of the lushest Mediterranean vegetation and views. Yet another aspect of Terracina’s historical background is the protracted terrifying presence of notorious bandits such as Fra Diavolo and Gasbarrone.This article questions the imagological implications of these mytho-cultural assets of Terracina in literature, with a focus on ‘Romantic’ early Nineteen Century travel literature at large (Irving Washington, Stendhal, in which the point of view is mostly from a visitor's perspective, whereas authoritative studies, e.g. by Eric Hobsbawm, have rightly stressed the crucial importance of the insiders’ point of view as well.As an excursus from this cultural and historical context Pier Paolo Pasolini’s delicious ‘Terracina’ comes in to offer just such an insider’s point of view, telling the story of two Roman ‘ragazzi di vita’ – or ‘briganti’, as the villagers call them – who become tourists themselves and get fatally attracted by the idyllic Terracina seascape.

  12. A grand unified model for liganded gold clusters

    Xu, Wen Wu; Zhu, Beien; Zeng, Xiao Cheng; Gao, Yi

    2016-12-01

    A grand unified model (GUM) is developed to achieve fundamental understanding of rich structures of all 71 liganded gold clusters reported to date. Inspired by the quark model by which composite particles (for example, protons and neutrons) are formed by combining three quarks (or flavours), here gold atoms are assigned three `flavours' (namely, bottom, middle and top) to represent three possible valence states. The `composite particles' in GUM are categorized into two groups: variants of triangular elementary block Au3(2e) and tetrahedral elementary block Au4(2e), all satisfying the duet rule (2e) of the valence shell, akin to the octet rule in general chemistry. The elementary blocks, when packed together, form the cores of liganded gold clusters. With the GUM, structures of 71 liganded gold clusters and their growth mechanism can be deciphered altogether. Although GUM is a predictive heuristic and may not be necessarily reflective of the actual electronic structure, several highly stable liganded gold clusters are predicted, thereby offering GUM-guided synthesis of liganded gold clusters by design.

  13. Salmonellosis in Rio Grande do Sul, Brazil, 1997 to 1999

    Costalunga Suzana

    2002-01-01

    Full Text Available Salmonella spp. was the major cause of reported foodborne diseases in the last years in the State of Rio Grande do Sul, South of Brazil. Epidemiological data on salmonellosis, occurred in the period of 1997 to 1999 and supplied by the Division of Sanitary Surveillance (DVS/RS, were analysed according to the following factors: total number of confirmed outbreaks, number of people involved, outbreaks incidence according to the period of the year, age and sex of involved people, food vehicle, food storage conditions, local where the disease occurred, and possible causes of the outbreaks. The results indicated that 8217 people were involved, and 1557 had to be hospitalized. The highest number of outbreaks occurred during springtime and the principal age group affected was between 16 and 50 years. The most common food vehicle was salad prepared with homemade mayonnaise (42.45%. The principal causes of salmonellosis were raw-materials not submitted to regulatory inspection (22.92%, mainly eggs, and foods maintained at room temperature for more than 2 hours (20.55%. The majority of the outbreaks occurred in private homes (43.70% and commercial food establishments (25.21%.

  14. Grand Challenges in Clinical Decision Support v10

    Sittig, Dean F.; Wright, Adam; Osheroff, Jerome A.; Middleton, Blackford; Teich, Jonathan M.; Ash, Joan S.; Campbell, Emily; Bates, David W.

    2008-01-01

    There is a pressing need for high-quality, effective means of designing, developing, presenting, implementing, evaluating, and maintaining all types of clinical decision support capabilities for clinicians, patients and consumers. Using an iterative, consensus-building process we identified a rank-ordered list of the top 10 grand challenges in clinical decision support. This list was created to educate and inspire researchers, developers, funders, and policy-makers. The list of challenges in order of importance that they be solved if patients and organizations are to begin realizing the fullest benefits possible of these systems consists of: Improve the human-computer interface; Disseminate best practices in CDS design, development, and implementation; Summarize patient-level information; Prioritize and filter recommendations to the user; Create an architecture for sharing executable CDS modules and services; Combine recommendations for patients with co-morbidities; Prioritize CDS content development and implementation; Create internet-accessible clinical decision support repositories; Use freetext information to drive clinical decision support; Mine large clinical databases to create new CDS. Identification of solutions to these challenges is critical if clinical decision support is to achieve its potential and improve the quality, safety and efficiency of healthcare. PMID:18029232

  15. Grand canonical validation of the bipartite international trade network

    Straka, Mika J.; Caldarelli, Guido; Saracco, Fabio

    2017-08-01

    Devising strategies for economic development in a globally competitive landscape requires a solid and unbiased understanding of countries' technological advancements and similarities among export products. Both can be addressed through the bipartite representation of the International Trade Network. In this paper, we apply the recently proposed grand canonical projection algorithm to uncover country and product communities. Contrary to past endeavors, our methodology, based on information theory, creates monopartite projections in an unbiased and analytically tractable way. Single links between countries or products represent statistically significant signals, which are not accounted for by null models such as the bipartite configuration model. We find stable country communities reflecting the socioeconomic distinction in developed, newly industrialized, and developing countries. Furthermore, we observe product clusters based on the aforementioned country groups. Our analysis reveals the existence of a complicated structure in the bipartite International Trade Network: apart from the diversification of export baskets from the most basic to the most exclusive products, we observe a statistically significant signal of an export specialization mechanism towards more sophisticated products.

  16. Evaluation of severe accident risks, Grand Gulf, Unit 1: Appendices

    Brown, T.D.; Breeding, R.J.; Jow, H.N.; Higgins, S.J.; Shiver, A.W.; Helton, J.C.; Amos, C.N.

    1990-12-01

    In support of the Nuclear Regulatory Commission's (NRC's) assessment of the risk from severe accidents at commercial nuclear power plants in the US report in NUREG-1150, the Severe Accident Risk Reduction Program (SARRP) has completed a revised calculation of the risk to the general public from severe accidents at the Grand Gulf Nuclear Station, Unit 1. This power plant, located in Port Gibson, Mississippi, is operated by the System Energy Resources, Inc. (SERI). The emphasis in this risk analysis was not on determining a ''so-called'' point estimate of risk. Rather, it was to determine the distribution of risk, and to discover the uncertainties that account for the breadth of this distribution. Off-site risk initiated by events internal to the power plant was assessed. This document provides Appendices A through E for this report. Topics included are, respectively: supporting information for the accident progression analysis; supporting information for the source term analysis; supporting information for the consequence analysis; risk results; and sampling information

  17. Environmental Audit, Rifle, Gunnison and Grand Junction UMTRA Project Sites

    1991-08-01

    This report documents the results of the comprehensive baseline Environmental Audit completed for the Uranium Mill Tailings Remedial Action (UMTRA) sites at Grand Junction, Rifle, and Gunnison, Colorado. Included in the Audit were the actual abandoned mill sites, associated transportation and disposal cell facilities, and representative examples of the more than 4,000 known vicinity properties. Sites investigated include: Climax Mill Site, Truck/Train Haul Route, Cotter Transfer Station, Cheney Disposal Cell, Rifle Mill Sites (Old and New Rifle), Gunnison Mill Site, Vicinity Properties, and Estes Gulch and Proposed Landfill Site No. 1 Disposal Cells. The UMTRA Audit was a comprehensive baseline audit which considered all environmental programs and the activities associated with ongoing and planned remediation at the UMTRA sites listed above. Compliance with the National Environmental Policy Act (NEPA) was not considered during this investigation. The Audit Team looked at the following technical disciplines: air, surface water/drinking water, groundwater, soil/sediment/biota, waste management, toxic and chemical materials, quality assurance, radiation, inactive waste sites, and environmental management. 6 figs., 12 tabs

  18. Grand unification and the double beta-decay

    Faessler, A.

    1992-01-01

    Models of the unification of the electroweak and the strong interaction predict that the neutrino is a Majorana particle and therefore essentially identical with its own antiparticle. In such grand unified models the neutrino has also a finite mass and a slight right-handed weak interaction, since the model is left-right symmetric. These models have also left handed and right-handed vector bosons to mediate the weak interactions. If these models are correct the neutrinoless double beta-decay is feasable. Thus if one finds the neutrinoless double beta-decay one knows that the standard model can not be correct in which the neutrino is a Dirac particle and therefore different from its antiparticle. Although the neutrinoless double beta-decay has not been seen it is possible to extract from the lower limits of the lifetime against the double neutrinoless beta-decay upper limits for the effective electron-neutrino mass and for the effective mixing angle of the right-handed and the left-handed vector bosons mediating the weak interaction. One also can obtain an effective upper limit for the mass ratio of the light and the heavy vector bosons. The extraction of this physical quantities from the data is made difficult due to the fact that the weak interaction must not be diagonal in the representation of the mass matrix of the six neutrinos requested by such left-right symmetric models. (author)

  19. Grand canonical validation of the bipartite international trade network.

    Straka, Mika J; Caldarelli, Guido; Saracco, Fabio

    2017-08-01

    Devising strategies for economic development in a globally competitive landscape requires a solid and unbiased understanding of countries' technological advancements and similarities among export products. Both can be addressed through the bipartite representation of the International Trade Network. In this paper, we apply the recently proposed grand canonical projection algorithm to uncover country and product communities. Contrary to past endeavors, our methodology, based on information theory, creates monopartite projections in an unbiased and analytically tractable way. Single links between countries or products represent statistically significant signals, which are not accounted for by null models such as the bipartite configuration model. We find stable country communities reflecting the socioeconomic distinction in developed, newly industrialized, and developing countries. Furthermore, we observe product clusters based on the aforementioned country groups. Our analysis reveals the existence of a complicated structure in the bipartite International Trade Network: apart from the diversification of export baskets from the most basic to the most exclusive products, we observe a statistically significant signal of an export specialization mechanism towards more sophisticated products.

  20. Insomnia and hypnotic use in Campo Grande general population, Brazil

    Souza José Carlos

    2002-01-01

    Full Text Available The insomnia prevalence in general population was determined by means of 408 home interviews of adults, in a representative sample of Campo Grande city, Brazil. The random sample was stratified by sex, age and economic social status. Insomnia subtypes evaluated were the disorders of sleep initiation (DSI, sleep maintenance (DSM and early awakening (DEA. A structured questionnaire was used with the consent from the interviewed subjects. Statistics used chi-square, and Fisher tests; and inferences based on binomial distribution parameters; the significance level was 5% and confidence interval (CI was 95%.The general prevalence of insomnia was 19.1% (sd=2.0%, mostly women (p=0.0015, and people of less years of schooling (p=0.0317, subtype DSI (14.2%, p=0.0043, and chronic (p=0.7022. Hypnotic drugs were used by 6.9%(sd=1.3% in the last month. Use in the last 2 years, 70.3% mostly insomniacs (p<0.0001, women (p=0.0372 and people over 30 years of age (p=0.0536.

  1. Environmental Audit, Rifle, Gunnison and Grand Junction UMTRA Project Sites

    None

    1991-08-01

    This report documents the results of the comprehensive baseline Environmental Audit completed for the Uranium Mill Tailings Remedial Action (UMTRA) sites at Grand Junction, Rifle, and Gunnison, Colorado. Included in the Audit were the actual abandoned mill sites, associated transportation and disposal cell facilities, and representative examples of the more than 4,000 known vicinity properties. Sites investigated include: Climax Mill Site, Truck/Train Haul Route, Cotter Transfer Station, Cheney Disposal Cell, Rifle Mill Sites (Old and New Rifle), Gunnison Mill Site, Vicinity Properties, and Estes Gulch and Proposed Landfill Site No. 1 Disposal Cells. The UMTRA Audit was a comprehensive baseline audit which considered all environmental programs and the activities associated with ongoing and planned remediation at the UMTRA sites listed above. Compliance with the National Environmental Policy Act (NEPA) was not considered during this investigation. The Audit Team looked at the following technical disciplines: air, surface water/drinking water, groundwater, soil/sediment/biota, waste management, toxic and chemical materials, quality assurance, radiation, inactive waste sites, and environmental management. 6 figs., 12 tabs.

  2. I cataloghi nella letteratura americana della Grande Depressione

    Cinzia Scarpino

    2011-07-01

    Full Text Available Il presente saggio si propone di analizzare alcune opere letterarie in senso lato (poesie, libri-documentario, script di film-documetario scritte negli Stati Uniti negli anni della Grande Depressione (1929-1941 alla luce della presenza ricorrente di cataloghi, liste e inventari. Partendo da un excursus storico circa la centralità del catalogo come forma narrativa atta a rendere l’abbondanza del Nuovo Mondo nella cultura e nella letteratura dell’Ottocento (dai diari dei primi esploratori agli scritti di Thomas Jefferson, dalle geremiadi puritane agli almanacchi e ai diari rurali, dalle teorizzazioni estetiche di Ralph Waldo Emerson al «poeta catalogatore» Walt Whitman e al Walden di H. D. Thoreau, il saggio si sofferma su alcune opere-documentario degli anni Trenta del Novecento; un periodo che, segnato profondamente dalla crisi economica e testimone di una riconfigurazione della geografia reale e simbolica del territorio nazionale, punta nuovamente a cataloghi e inventari, secondo una scelta retorica funzionale alla rappresentazione del rovescio del mito di abbondanza delle origini.

  3. Domain walls and fermion scattering in grand unified models

    Steer, D.A.; Vachaspati, T.

    2006-01-01

    Motivated by grand unification, we study the properties of domain walls formed in a model with SU(5)xZ 2 symmetry which is spontaneously broken to SU(3)xSU(2)xU(1)/Z 6 , and subsequently to SU(3)xU(1)/Z 3 . Even after the first stage of symmetry breaking, the SU(3) symmetry is broken to SU(2)xU(1)/Z 2 on the domain wall. In a certain range of parameters, flux tubes carrying color- and hyper-charge live on the domain wall and appear as 'boojums' when viewed from one side of the domain wall. Magnetic monopoles are also formed in the symmetry breaking and those carrying color and hyper-charge can be repelled from the wall due to the Meissner effect, or else their magnetic flux can penetrate the domain wall in quantized units. After the second stage of symmetry breaking, fermions can transmute when they scatter with the domain wall, providing a simpler version of fermion-monopole scattering: for example, neutrinos can scatter into d-quarks, leaving behind electric charge and color which is carried by gauge field excitations living on the domain wall

  4. Dark matter as the signal of grand unification

    Kadastik, Mario; Kannike, Kristjan; Raidal, Martti

    2009-01-01

    We argue that the existence of dark matter (DM) is a possible consequence of grand unification (GUT) symmetry breaking. In GUTs like SO(10), discrete Z 2 matter parity (-1) 3(B-L) survives despite broken B-L, and group theory uniquely determines that the only possible Z 2 -odd matter multiplets belong to representation 16. We construct the minimal nonsupersymmetric SO(10) model containing one scalar 16 for DM and study its predictions below M G . We find that electroweak symmetry breaking occurs radiatively due to DM couplings to the standard model Higgs boson. For thermal relic DM the mass range M DM ∼O(0.1-1) TeV is predicted by model perturbativity up to M G . For M DM ∼O(1) TeV to explain the observed cosmic ray anomalies with DM decays, there exists a lower bound on the spin-independent direct detection cross section within the reach of planned experiments.

  5. Il grande Gatsby: note a margine di una traduzione

    Tommaso Pincio

    2014-05-01

    Full Text Available In questa breve nota lo scrittore e traduttore Tommaso Pincio riflette sul fascino esercitato da Il Grande Gatsby – libro e personaggio, il narratore e la lingua – su generazioni diverse di americani: quelle degli anni Venti, degli anni Cinquanta e di oggi. Commenti, aneddoti e citazioni guidano quell’esplorazione dello spirito del libro che ha permesso a Pincio di riprodurne lo stile per i lettori italiani. Questo contributo è originariamente apparso sul blog personale dell’autore, all’indirizzo http://tommasopincio.net.In this brief note, writer and translator Tommaso Pincio reflects on the haunting fascination exerted by The Great Gatsby – the book, the character, its narrator and language – on a range of American generations: those of the Twenties, of the Fifties, and the present one. Comments, anecdotes and quotations guide Pincio’s exploration into the spirit of the book, one that enabled him to reproduce its style for the Italian readership. This contribution first appeared on Pincio’s own blog, whose address is http://tommasopincio.net. 

  6. Improved grand canonical sampling of vapour-liquid transitions.

    Wilding, Nigel B

    2016-10-19

    Simulation within the grand canonical ensemble is the method of choice for accurate studies of first order vapour-liquid phase transitions in model fluids. Such simulations typically employ sampling that is biased with respect to the overall number density in order to overcome the free energy barrier associated with mixed phase states. However, at low temperature and for large system size, this approach suffers a drastic slowing down in sampling efficiency. The culprits are geometrically induced transitions (stemming from the periodic boundary conditions) which involve changes in droplet shape from sphere to cylinder and cylinder to slab. Since the overall number density does not discriminate sufficiently between these shapes, it fails as an order parameter for biasing through the transitions. Here we report two approaches to ameliorating these difficulties. The first introduces a droplet shape based order parameter that generates a transition path from vapour to slab states for which spherical and cylindrical droplets are suppressed. The second simply biases with respect to the number density in a tetragonal subvolume of the system. Compared to the standard approach, both methods offer improved sampling, allowing estimates of coexistence parameters and vapor-liquid surface tension for larger system sizes and lower temperatures.

  7. Education Research: An exploration of case-based learning in neuroscience grand rounds using the Delphi technique.

    Rigby, Heather; Schofield, Susie; Mann, Karen; Benstead, Timothy

    2012-07-17

    Neuroscience grand rounds (NSGR) is a key educational exercise in most academic medical centers. Despite its importance, there are few published studies evaluating the manner in which it is conducted. Our objective was to obtain consensus opinion from staff neurologists, neurosurgeons, neuroradiologists, and neuropathologists on the features that best characterize a highly educational NSGR. Using the Delphi technique, multiple rounds of questionnaires were presented to a panel of neurologists, neurosurgeons, neuropathologists, and neuroradiologists. The anonymous responses were analyzed and fed back to participants. Each round, the participants were given the opportunity to react to collective opinion by changing their response or by presenting arguments in favor or against the item in question. We found that support for NSGR in its present form is high and that particularly strong support exists for 1) case-based rounds, 2) high level of audience interaction, 3) resident participation in case presentation and analysis, 4) formal training for residents in leading case-based presentations, and 5) resident feedback and evaluation. Our results offer centers that use a case-based format for NSGR with guidance to maximize the important learning opportunity that it provides. We provide an organized evaluation of expert opinion on how this important educational exercise should be conducted. The results expose some fresh insights into traditional values in medical education.

  8. Yuntaishan Global Geopark VS Grand Canyon World Heritage Site A Contrast of Yuntai/Grand Canyon Physiognomy

    Ting, Zhao; Xun, Zhao

    2017-04-01

    Yuntai/Grand Canyon is a result of long-term historical evolution and a rare natural heritage of the world. With its rich heritages of geological physiognomy, systematic geological record, abundant biological fossil combination, long history of structural evolution, they are of contrastive research values worldwide. The Grand Canyon was declared national natural heritage on eleventh January, and in 1979 it was entitled World Natural Heritage Site. Though the two major sites are separated by tremendous seas, they reached agreements in the protection of natural heritages worldwide on account of the shared ideas of society, demonstrating to our children how can we protect the two scenery sites. Keyword:Geopark, Geoheritage, Yuntai Landform, GrandCanyon Mt. Taihang rises from the central part of north China and extends to the west edge of North China Plain. Towering, and with ragged peaks, precarious cliffs, long strips of walls, deep valleys and shaded streams, Mt. Taihang poses impressive sights with its clear water, dense forest and wonderful sceneries. It is indeed the east slope of Qin-Jin Plateau. Indeed things tend to coincide. On the other side of the Pacific Ocean, along the west edge of north America and on the wide and spacious Colorado Plateau, there is a winding and deep valley where there are layers of rocks, extensive sharp cliffs, intercrossing ravines and forests of peaks; it is totally impressive. Both sceneries are known to the world for their beauty. Identical geological conditions and similar history of evolution left two natural sights that resemble each other so much. Geological changes are infinite, and sedimentation works in similar ways on both sights; and the changing ecological environment gives the world two colorful and comparable geological records. Both sights are merely brief periods in the long history of earth development, but they show us how cradles of human proliferation and social civilization had looked. 1,Comparison of two parks

  9. Proliferation marker pKi-67 affects the cell cycle in a self-regulated manner.

    Schmidt, Mirko H H; Broll, Rainer; Bruch, Hans-Peter; Duchrow, Michael

    2002-01-01

    The proliferation marker pKi-67 is commonly used in research and pathology to detect proliferating cells. In a previous work, we found the protein to be associated with regulators of the cell cycle, controlling S-phase progression, as well as entry into and exit from mitosis. Here we investigate whether pKi-67 has a regulative effect on the cell cycle itself. For that purpose we cloned four fragments of pKi-67, together representing nearly the whole protein, and an N-terminal pKi-67 antisense oligonucleotide into a tetracycline inducible gene expression system. The sense fragments were C-terminally modified by addition of either a nuclear localization sequence (NLS) or a STOP codon to address the impact of their intracellular distribution. FACS based cell cycle analysis revealed that expression of nearly all pKi-67 domains and the antisense oligonucleotide led to a decreased amount of cells in S-phase and an increased number of cells in G(2)/M- and G(1)-phase. Subsequent analysis of the endogenous pKi-67 mRNA and protein levels revealed that the constructs with the most significant impact on the cell cycle were able to silence pKi-67 transcription as well. We conclude from the data that pKi-67 influences progression of S-phase and mitosis in a self-regulated manner and, therefore, effects the cell cycle checkpoints within both phases. Furthermore, we found pKi-67 mediates an anti-apoptotic effect on the cell and we verified that this marker, although it is a potential ribosomal catalyst, is not expressed in differentiated tissues with a high transcriptional activity. Copyright 2002 Wiley-Liss, Inc.

  10. Isoproterenol Increases RANKL Expression in a ATF4/NFATc1-Dependent Manner in Mouse Osteoblastic Cells

    Kyunghwa Baek

    2017-10-01

    Full Text Available Sympathetic nervous system stimulation-induced β-adrenergic signal transduction is known to induce bone loss and increase of osteoclast activity. Although isoproterenol, a nonspecific β-adrenergic receptor agonist, has been shown to increase receptor activator of NF-κB ligand (RANKL, the details of the regulatory mechanisms remain unclear. In the present study, we investigated the role of the nuclear factor of activated T-cells (NFAT in isoproterenol-induced RANKL expression in C2C12 and in primary cultured mouse calvarial cells. Isoproterenol increased nuclear factor of activated T-cells cytoplasmic 1 (NFATc1 and RANKL expressions at both mRNA and protein levels and increased NFAT reporter activity. NFATc1 knockdown blocked isoproterenol-mediated RANKL expression. Isoproterenol also promoted cAMP response element-binding protein 1 (CREB1 and activating transcription factor 4 (ATF4 phosphorylation. Isoproterenol-mediated transcriptional activation of NFAT was blocked by protein kinase A (PKA inhibitor H89. Isoproterenol-induced CREB1, ATF4, NFATc1, and RANKL expressions were suppressed by H89. Mutations in cAMP response element-like or NFAT-binding element suppressed isoproterenol-induced RANKL promoter activity. Chromatin immunoprecipitation analysis demonstrated that isoproterenol increased NFAT-binding and ATF4-binding activities on the mouse RANKL promoter, but did not increase CREB1-binding activity. Association of NFATc1 and ATF4 was not observed in a co-immunoprecipitation study. ATF4 knockdown suppressed isoproterenol-induced NFAT binding to the RANKL promoter, whereas NFATc1 knockdown did not suppress isoproterenol-induced ATF4 binding to the RANKL promoter. ATF4 knockdown suppressed isoproterenol-induced expressions of NFATc1 and RANKL. These results suggest that isoproterenol increases RANKL expression in an ATF4/NFATc1-dependent manner.

  11. Relationship between the Manner of Mobile Phone Use and Depression, Anxiety, and Stress in University Students.

    Višnjić, Aleksandar; Veličković, Vladica; Sokolović, Dušan; Stanković, Miodrag; Mijatović, Kristijan; Stojanović, Miodrag; Milošević, Zoran; Radulović, Olivera

    2018-04-08

    Objectives : There is insufficient evidence regarding the potential risk of mobile phone use on mental health. Therefore, the aim of this research was to examine the relationship between mobile phone use and mental health by measuring the levels of depression, anxiety, and stress among university students in Serbia and Italy. Methods : This cross-sectional study was carried out at two distinguished universities in Serbia and Italy from March to May of the 2015/2016 academic year and included 785 students of both genders. The questionnaire was compiled and developed from different published sources regarding the manner and intensity of mobile phone use, along with the Depression Anxiety Stress Scale (DASS 42) for measuring psychological health. The statistical analysis of the data included the application of binary logistic regression and correlation tests. Results: Statistical analysis indicates that anxiety symptoms are somewhat more present in younger students (odds ratio (OR) = 0.86, 95% confidence interval (CI): 0.76-0.96), in those who send more text messages SMSs (OR = 1.15, 95% CI: 1.11-1.31), and in those who browse the internet less frequently (OR = 0.84, 95% CI: 0.73-0.95). Stress is more common in students who make fewer calls a day (OR = 0.79, 95% CI: 0.64-0.97), as well in those who spend more time talking on the mobile phone per day (OR = 1.28, 95% CI: 1.12-1.56). The strongest predictor of high stress levels was keeping the mobile phone less than 1 m away during sleeping (OR = 1.48, 95% CI: 1.12-2.08). Conclusions: The results indicated that the intensity and modality of mobile phone use could be a factor that can influence causal pathways leading to mental health problems in the university student population.

  12. Adiponectin influences progesterone production from MA-10 Leydig cells in a dose-dependent manner.

    Landry, David; Paré, Aurélie; Jean, Stéphanie; Martin, Luc J

    2015-04-01

    Obesity in men is associated with lower testosterone levels, related to reduced sperm concentration and the development of various diseases with aging. Hormones produced by the adipose tissue may have influences on both metabolism and reproductive function. Among them, the production and secretion of adiponectin is inversely correlated to total body fat. Adiponectin receptors (AdipoR1 and AdipoR2) have been found to be expressed in testicular Leydig cells (producing testosterone). Since StAR and Cyp11a1 are essential for testosterone synthesis and adiponectin has been shown to regulate StAR mRNA in swine granulosa cells, we hypothesized that adiponectin might also regulate these genes in Leydig cells. Our objective was to determine whether adiponectin regulates StAR and Cyp11a1 genes in Leydig cells and to better define its mechanisms of action. Methods used in the current study are qPCR for the mRNA levels, transfections for promoter activities, and enzyme-linked immunosorbent assay for the progesterone concentration. We have found that adiponectin cooperates with cAMP-dependent stimulation to activate StAR and Cyp11a1 mRNA expressions in a dose-dependent manner in MA-10 Leydig cells as demonstrated by transfection of a luciferase reporter plasmid. These results led to a significant increase in progesterone production from MA-10 cells. Thus, our data suggest that high doses of adiponectin typical of normal body weight may promote testosterone production from Leydig cells.

  13. IGFBP-4 regulates adult skeletal growth in a sex-specific manner.

    Maridas, David E; DeMambro, Victoria E; Le, Phuong T; Nagano, Kenichi; Baron, Roland; Mohan, Subburaman; Rosen, Clifford J

    2017-04-01

    Insulin-like growth factor-1 (IGF-1) and its binding proteins are critical mediators of skeletal growth. Insulin-like growth factor-binding protein 4 (IGFBP-4) is highly expressed in osteoblasts and inhibits IGF-1 actions in vitro Yet, in vivo studies suggest that it could potentiate IGF-1 and IGF-2 actions. In this study, we hypothesized that IGFBP-4 might potentiate the actions of IGF-1 on the skeleton. To test this, we comprehensively studied 8- and 16-week-old Igfbp4 -/- mice. Both male and female adult Igfbp4 -/- mice had marked growth retardation with reductions in body weight, body and femur lengths, fat proportion and lean mass at 8 and 16 weeks. Marked reductions in aBMD and aBMC were observed in 16-week-old Igfbp4 -/- females, but not in males. Femoral trabecular BV/TV and thickness, cortical fraction and thickness in 16-week-old Igfbp4 -/- females were significantly reduced. However, surprisingly, males had significantly more trabeculae with higher connectivity density than controls. Concordantly, histomorphometry revealed higher bone resorption and lower bone formation in Igfbp4 -/- females. In contrast, Igfbp4 -/- males had lower mineralized surface/bone surface. Femoral expression of Sost and circulating levels of sclerostin were reduced but only in Igfbp4 -/- males. Bone marrow stromal cultures from mutants showed increased osteogenesis, whereas osteoclastogenesis was markedly increased in cells from Igfbp4 -/- females but decreased in males. In sum, our results indicate that loss of Igfbp4 affects mesenchymal stromal cell differentiation, regulates osteoclastogenesis and influences both skeletal development and adult bone maintenance. Thus, IGFBP-4 modulates the skeleton in a gender-specific manner, acting as both a cell autonomous and cell non-autonomous factor. © 2017 The authors.

  14. A time-dependent degeneration manner of condyle in rat CFA-induced inflamed TMJ.

    Xu, Liqin; Guo, Huilin; Li, Cheng; Xu, Jie; Fang, Wei; Long, Xing

    2016-01-01

    Temporomandibular joint (TMJ) inflammation is a potential risk factor of osteoarthritis (OA) but the detailed degenerative changes in the inflamed TMJ remain unclear. In this study, we evaluated the changes of condylar cartilage and subchondral bone in rat inflamed TMJ induced by Freund's complete adjuvant (CFA). Articular cavity was injected with CFA and the TMJ samples were collected 1, 2, 3, and 4-week post-injection. Hematoxylin & Eosin (H&E) staining, toluidine blue (TB) staining, Safranin O (S.O) staining, Masson trichrome staining and micro-CT were used to assess TMJ degeneration during inflammation. Osteoclast and osteoblast activities were analyzed by tartrate-resistant acid phosphatase (TRAP) staining and osteocalcin (OCN) immunohistochemistry staining respectively. The expression of receptor activator of NF-kB ligand (RANKL) and osteoprotegerin (OPG) in condylar cartilage and subchondral bone was also evaluated through immunohistochemistry and RANKL/OPG ratio was evaluated. Reduced cartilage thickness, decreased number of chondrocytes, and down-regulated proteoglycan expression were observed in the condylar cartilage in the inflamed TMJ. Enhanced osteoclast activity, and expanded bone marrow cavity were reached the peak in the 2-week after CFA-injection. Meanwhile the RANKL/OPG ratio in the cartilage and subchondral bone also increased in the 2-week CFA-injection. Immature, unmineralized new bones with irregular trabecular bone structure, atypical condylar shape, up-regulated OCN expression, and decreased bone mineral density (BMD) were found in the inflamed TMJ. The time-dependent degeneration manner of TMJ cartilage and subchondral bone was found in CFA-induced arthritis rat model. The degeneration in the TMJ with inflammation might be a risk factor and should be concerned.

  15. Apolipoprotein A-IV constrains HPA and behavioral stress responsivity in a strain-dependent manner.

    Packard, Amy E B; Zhang, Jintao; Myers, Brent; Ko, Chih-Wei; Wang, Fei; Tso, Patrick; Ulrich-Lai, Yvonne M

    2017-12-01

    There is a critical gap in our knowledge of the mechanisms that govern interactions between daily life experiences (e.g., stress) and metabolic diseases, despite evidence that stress can have profound effects on cardiometabolic health. Apolipoprotein A-IV (apoA-IV) is a protein found in chylomicrons (lipoprotein particles that transport lipids throughout the body) where it participates in lipid handling and the regulation of peripheral metabolism. Moreover, apoA-IV is expressed in brain regions that regulate energy balance including the arcuate nucleus. Given that both peripheral and central metabolic processes are important modulators of hypothalamic-pituitary-adrenocortical (HPA) axis activity, the present work tests the hypothesis that apoA-IV activity affects stress responses. As emerging data suggests that apoA-IV actions can vary with background strain, we also explore the strain-dependence of apoA-IV stress regulation. These studies assess HPA axis, metabolic (hyperglycemia), and anxiety-related behavioral responses to psychogenic stress in control (wildtype) and apoA-IV-deficient (KO) mice on either the C57Bl/6J (C57) or 129×1/SvJ (129) background strain. The results indicate that apoA-IV KO increases post-stress corticosterone and anxiety-related behavior specifically in the 129 strain, and increases stress-induced hyperglycemia exclusively in the C57 strain. These data support the hypothesis that apoA-IV is a novel factor that limits stress reactivity in a manner that depends on genetic background. An improved understanding of the complex relationship among lipid homeostasis, stress sensitivity, and genetics is needed to optimize the development of personalized treatments for stress- and metabolism-related diseases. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Relationship between the Manner of Mobile Phone Use and Depression, Anxiety, and Stress in University Students

    Višnjić, Aleksandar; Veličković, Vladica; Sokolović, Dušan; Stanković, Miodrag; Stojanović, Miodrag; Milošević, Zoran; Radulović, Olivera

    2018-01-01

    Objectives: There is insufficient evidence regarding the potential risk of mobile phone use on mental health. Therefore, the aim of this research was to examine the relationship between mobile phone use and mental health by measuring the levels of depression, anxiety, and stress among university students in Serbia and Italy. Methods: This cross-sectional study was carried out at two distinguished universities in Serbia and Italy from March to May of the 2015/2016 academic year and included 785 students of both genders. The questionnaire was compiled and developed from different published sources regarding the manner and intensity of mobile phone use, along with the Depression Anxiety Stress Scale (DASS 42) for measuring psychological health. The statistical analysis of the data included the application of binary logistic regression and correlation tests. Results: Statistical analysis indicates that anxiety symptoms are somewhat more present in younger students (odds ratio (OR) = 0.86, 95% confidence interval (CI): 0.76–0.96), in those who send more text messages (SMSs) (OR = 1.15, 95% CI: 1.11–1.31), and in those who browse the internet less frequently (OR = 0.84, 95% CI: 0.73–0.95). Stress is more common in students who make fewer calls a day (OR = 0.79, 95% CI: 0.64–0.97), as well in those who spend more time talking on the mobile phone per day (OR = 1.28, 95% CI: 1.12–1.56). The strongest predictor of high stress levels was keeping the mobile phone less than 1 m away during sleeping (OR = 1.48, 95% CI: 1.12–2.08). Conclusions: The results indicated that the intensity and modality of mobile phone use could be a factor that can influence causal pathways leading to mental health problems in the university student population. PMID:29642471

  17. Metformin decreases lung cancer risk in diabetic patients in a dose-dependent manner.

    Tsai, Ming-Ju; Yang, Chih-Jen; Kung, Ya-Ting; Sheu, Chau-Chyun; Shen, Yu-Ting; Chang, Pi-Yu; Huang, Ming-Shyan; Chiu, Herng-Chia

    2014-11-01

    Higher risk of lung cancer has been noted in patients with type 2 diabetes mellitus (DM). Some observational studies have shown a reduced risk of lung cancer in DM patients taking metformin, but a dose-response relationship has never been reported. The aim of this study is to exam the association between the dose of metformin and the incidence of lung cancer in a Chinese population. The dataset used for this nationwide population-based study is a cohort of 1 million subjects randomly sampled from individuals enrolled in the Taiwan National Health Insurance system. We enrolled all subjects with newly diagnosed type 2 DM between 1997 and 2007. Subjects with a diagnosis of neoplasm before DM diagnosis, those using metformin before DM diagnosis, those with polycystic ovary syndrome, and those with a DM diagnosis before their 15 years of age were excluded. The demographic data and duration, cumulative dose and intensity of metformin use were compared between patients developing lung cancer and those without lung cancer. Totally, 47,356 subjects were identified. After adjusting for age, gender, and modified Charlson Comorbidity Index score, the utilization of metformin was an independent protecting factor, and the risk of developing lung cancer decreased progressively with either the higher cumulative dose or the higher intensity of metformin use. This study revealed that the use of metformin decreased the risk of lung cancer in a dose-dependent manner in patients with type 2 DM. The chemo-preventive effect of metformin deserves further study. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  18. Dopamine D3 receptor knockout mice exhibit abnormal nociception in a sex-different manner.

    Liu, Peng; Xing, Bo; Chu, Zheng; Liu, Fei; Lei, Gang; Zhu, Li; Gao, Ya; Chen, Teng; Dang, Yong-Hui

    2017-07-01

    Pain is a complex and subjective experience. Previous studies have shown that mice lacking the dopamine D3 receptor (D3RKO) exhibit hypoalgesia, indicating a role of the D3 receptor in modulation of nociception. Given that there are sex differences in pain perception, there may be differences in responses to nociceptive stimuli between male and female D3RKO mice. In the current study, we examined the role of the D3 receptor in modulating nociception in male and female D3RKO mice. Acute thermal pain was modeled by hot-plate test. This test was performed at different temperatures including 52°C, 55°C, and 58°C. The von Frey hair test was applied to evaluate mechanical pain. And persistent pain produced by peripheral tissue injury and inflammation was modeled by formalin test. In the hot-plate test, compared with wild-type (WT) mice, D3RKO mice generally exhibited longer latencies at each of the three temperatures. Specially, male D3RKO mice showed hypoalgesia compared with male WT mice when the temperature was 55°C, while for the female mice, there was a statistical difference between genotypes when the test condition was 52°C. In the von Frey hair test, both male and female D3RKO mice exhibited hypoalgesia. In the formalin test, the male D3RKO mice displayed a similar nociceptive behavior as their sex-matched WT littermates, whereas significantly depressed late-phase formalin-induced nociceptive behaviors were observed in the female mutants. These findings indicated that the D3 receptor affects nociceptive behaviors in a sex-specific manner and that its absence induces more analgesic behavior in the female knockout mice. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  19. Maternal prenatal cortisol predicts infant negative emotionality in a sex-dependent manner.

    Braithwaite, Elizabeth C; Pickles, Andrew; Sharp, Helen; Glover, Vivette; O'Donnell, Kieran J; Tibu, Florin; Hill, Jonathan

    2017-06-01

    Prenatal stress influences fetal developmental trajectories, which may implicate glucocorticoid mechanisms. There is also emerging evidence that effects of prenatal stress on offspring development are sex-dependent. However, little is known about the prospective relationship between maternal prenatal cortisol levels and infant behaviour, and whether it may be different in male and female infants. We sought to address this question using data from a prospective longitudinal cohort, stratified by risk. The Wirral Child Health and Development Study (WCHADS) cohort (n=1233) included a stratified random sub-sample (n=216) who provided maternal saliva samples, assayed for cortisol, at home over two days at 32weeks of pregnancy (on waking, 30-min post-waking and during the evening) and a measure of infant negative emotionality from the Neonatal Behavioural Assessment Scale (NBAS) at five weeks-of-age. General population estimates of associations among measures were obtained using inverse probability weights. Maternal prenatal cortisol sampled on waking predicted infant negative emotionality in a sex-dependent manner (interaction term, p=0.005); female infants exposed to high levels of prenatal cortisol were more negative (Beta=0.440, p=0.042), whereas male infants were less negative (Beta=-0.407, p=0.045). There was no effect of the 30-min post-waking measure or evening cortisol. Our findings add to an emerging body of work that has highlighted sex differences in fetal programming, whereby females become more reactive following prenatal stress, and males less reactive. A more complete understanding of sex-specific developmental trajectories in the context of prenatal stress is essential for the development of targeted prevention strategies. Copyright © 2017. Published by Elsevier Inc.

  20. Listeria monocytogenes alters mast cell phenotype, mediator and osteopontin secretion in a listeriolysin-dependent manner.

    Catherine E Jobbings

    Full Text Available Whilst mast cells participate in the immune defence against the intracellular bacterium Listeria monocytogenes, there is conflicting evidence regarding the ability of L. monocytogenes to infect mast cells. It is known that the pore-forming toxin listeriolysin (LLO is important for mast cell activation, degranulation and the release of pro-inflammatory cytokines. Mast cells, however, are a potential source of a wide range of cytokines, chemokines and other mediators including osteopontin, which contributes to the clearing of L. monocytogenes infections in vivo, although its source is unknown. We therefore aimed to resolve the controversy of mast cell infection by L. monocytogenes and investigated the extent of mediator release in response to the bacterium. In this paper we show that the infection of bone marrow-derived mast cells by L. monocytogenes is inefficient and LLO-independent. LLO, however, is required for calcium-independent mast cell degranulation as well as for the transient and selective downregulation of cell surface CD117 (c-kit on mast cells. We demonstrate that in addition to the key pro-inflammatory cytokines TNF-α and IL-6, mast cells release a wide range of other mediators in response to L. monocytogenes. Osteopontin, IL-2, IL-4, IL-13 and granulocyte macrophage colony-stimulating factor (GM-CSF, and chemokines including CCL2, CCL3, CCL4 and CCL5 are released in a MyD88-dependent manner. The wide range of mediators released by mast cells in response to L. monocytogenes may play an important role in the recruitment and activation of a variety of immune cells in vivo. The cocktail of mediators, however, is unlikely to skew the immune response to a particular effector response. We propose that mast cells provide a hitherto unreported source of osteopontin, and may provide an important role in co-ordinating the immune response during Listeria infection.

  1. Neuron-astrocyte interaction enhance GABAergic synaptic transmission in a manner dependent on key metabolic enzymes.

    Przemysław eKaczor

    2015-04-01

    Full Text Available GABA is the major inhibitory neurotransmitter in the adult brain and mechanisms of GABAergic inhibition have been intensely investigated in the past decades. Recent studies provided evidence for an important role of astrocytes in shaping GABAergic currents. One of the most obvious, but yet poorly understood, mechanisms of the cross-talk between GABAergic currents and astrocytes is metabolism including neurotransmitter homeostasis. In particular, how modulation of GABAergic currents by astrocytes depends on key enzymes involved in cellular metabolism remains largely unknown. To address this issue, we have considered two simple models of neuronal cultures: nominally astrocyte-free neuronal culture (NC and neuronal-astrocytic co-cultures (ANCC and miniature Inhibitory Postsynaptic Currents (mIPSCs were recorded in control conditions and in the presence of respective enzyme blockers. We report that enrichment of neuronal culture with astrocytes results in a marked increase in mIPSC frequency. This enhancement of GABAergic activity was accompanied by increased number of GAD65 and vGAT puncta, indicating that at least a part of the frequency enhancement was due to increased number of synaptic contacts. Inhibition of glutamine synthetase (with MSO strongly reduced mIPSC frequency in ANCC but had no effect in NC. Moreover, treatment of ANCC with inhibitor of glycogen phosphorylase (BAYU6751 or with selective inhibitor of astrocytic Krebs cycle,fluoroacetate, resulted in a marked reduction of mIPSC frequency in ANCC having no effect in NC. We conclude that GABAergic synaptic transmission strongly depends on neuron-astrocyte interaction in a manner dependent on key metabolic enzymes as well as on the Krebs cycle.

  2. The Role Of The «Grand Schools» And The «Grand Corps» As Recruitment Channels For French Ministers

    I. A. Zarankin

    2017-01-01

    Full Text Available The recruitment of ministers among high-ranking officials, who studied in the «grand schools» and worked in the «grand corps», is one of the typical traits of the Fifth republic. This is a consequence of the traditional interpenetration of French administrative and political elites. However, there is no common view on the actual role of these institutions in the ministers’ recruitment. So, the objective of this paper is to clarify this issue. For this purpose we analyze career trajectories of French ministers from 1981 till 2016. The data on each government include shares of ministers, who passed through the «grand schools» and the «grand corps». The article shows that nowadays the number of ministers with such an experience has decreased. Most government members are professional politicians, who have significant electoral experience and occupy high-ranking party positions. Today there are political parties, not the «grand schools» and the «grand corps», that are the main channels of the ministers’ recruitment. The professionalization of politics and reinforcement of the role of parties in the French political system are the most crucial factors of this tendency. The transformation of gaullists into liberals and conduction of the liberal economic policy, instead of the dirigist one, also contributed to replacement of officials by representatives of the private sector. Despite the fact that political parties serve as a main channel of the ministers’ recruitment, they face internal problems. The future role of political parties in the recruitment will depend on their ability to deal with these challenges.

  3. 78 FR 73559 - Moose-Wilson Corridor Comprehensive Management Plan, Environmental Impact Statement, Grand Teton...

    2013-12-06

    ...-Wilson Corridor Comprehensive Management Plan, Environmental Impact Statement, Grand Teton National Park... is preparing a Comprehensive Management Plan and Environmental Impact Statement (EIS) for the Moose...; (2) distinguish the corridor's fundamental and other important resources and values; (3) clearly...

  4. 76 FR 23623 - Backcountry Management Plan, Environmental Impact Statement, Grand Canyon National Park, Arizona

    2011-04-27

    ...-7945, [email protected] or Rachel Bennett, Environmental Protection Specialist, P.O. Box 129, Grand Canyon, Arizona 86023, 928-638-7326, Rachel[email protected] . SUPPLEMENTARY INFORMATION: If you wish to...

  5. 2017 NOAA/OCM Unmanned Aerial System Lidar: Grand Bay NERR

    National Oceanic and Atmospheric Administration, Department of Commerce — Quantum Spatial (QSI) and PrecisionHawk (PH) collected lidar for test sites within the Grand Bay National Estuarine Research Reserve (NERR) using an unmanned aerial...

  6. A BLUEPRINT FOR IMPLEMENTING GRAND CHALLENGE SCHOLARS’ PROGRAMME: A CASE STUDY OF TAYLOR’S UNIVERSITY

    MUSHTAK AL-ATABI

    2013-04-01

    Full Text Available The National Academy for Engineering announced 14 Grand Challenges for the 21st Century engineers to address in order to ensure a sustainable future for the generations to come. These grand challenges are in four broad areas, namely, energy and environment, health, security and learning and computation. This paper reports on a Grand Challenges Scholars’ Programme that is developed to prepare the engineering students to be able to address the grand challenges using the CDIO framework and focusing on five components; research experience, interdisciplinary curriculum, entrepreneurship, global dimension and service learning. The programme is voluntary and the candidates are expected to commit additional learning time. The programme was launched with 16 participants who are expected to graduate in 2016. A preliminary assessment of the programs shows that the participants found the programme useful in developing an array of CDIO skills. The School intends to continue offering this programme with the intention of integrating it with a holistic education approach.

  7. 2017 NOAA/OCM Unmanned Aerial System Lidar DEM: Grand Bay NERR

    National Oceanic and Atmospheric Administration, Department of Commerce — Quantum Spatial (QSI) and PrecisionHawk (PH) collected lidar for test sites within the Grand Bay National Estuarine Research Reserve (NERR) using an unmanned aerial...

  8. Grand Seasonal SST images of the Stellwagen Bank National Marine Sanctuary

    National Oceanic and Atmospheric Administration, Department of Commerce — Grand monthly mean Sea Surface Temperature http://podaac.jpl.nasa.gov/ Naming Convention: XXXX_SSSYYYY1YYYY2_GAVGSST.tif XXXX=location (Stell) SSS= season...

  9. Nekton usage in a Caminda Bay Saltmarsh at Grand Isle LA July and October 1998

    National Oceanic and Atmospheric Administration, Department of Commerce — During July and October 1988, a total of 42 samples were collected in salt marsh habitats of the Caminada Bay system near Grand Isle, Louisiana to evaluate the use...

  10. Urban Waters and the Middle Rio Grande/Albuquerque (New Mexico)

    Middle Rio Grande/Albuquerque (New Mexico) of the Urban Waters Federal Partnership (UWFP) reconnects urban communities with their waterways by improving coordination among federal agencies and collaborating with community-led efforts.

  11. 75 FR 7625 - Endangered and Threatened Wildlife and Plants; Rio Grande Silvery Minnow (Hybognathus amarus...

    2010-02-22

    ... modification of its habitat due to dewatering and diversion of water, water impoundment, and modification of... thorough knowledge of the Rio Grande silvery minnow's life history, ecology, and behavior, and the current...

  12. Behavioral stress alters corticolimbic microglia in a sex- and brain region-specific manner.

    Bollinger, Justin L; Collins, Kaitlyn E; Patel, Rushi; Wellman, Cara L

    2017-01-01

    Women are more susceptible to numerous stress-linked psychological disorders (e.g., depression) characterized by dysfunction of corticolimbic brain regions critical for emotion regulation and cognitive function. Although sparsely investigated, a number of studies indicate sex differences in stress effects on neuronal structure, function, and behaviors associated with these regions. We recently demonstrated a basal sex difference in- and differential effects of stress on- microglial activation in medial prefrontal cortex (mPFC). The resident immune cells of the brain, microglia are implicated in synaptic and dendritic plasticity, and cognitive-behavioral function. Here, we examined the effects of acute (3h/day, 1 day) and chronic (3h/day, 10 days) restraint stress on microglial density and morphology, as well as immune factor expression in orbitofrontal cortex (OFC), basolateral amygdala (BLA), and dorsal hippocampus (DHC) in male and female rats. Microglia were visualized, classified based on their morphology, and stereologically counted. Microglia-associated transcripts (CD40, iNOS, Arg1, CX3CL1, CX3CR1, CD200, and CD200R) were assessed in brain punches from each region. Expression of genes linked with cellular stress, neuroimmune state, and neuron-microglia communication varied between unstressed male and female rats in a region-specific manner. In OFC, chronic stress upregulated a wider variety of immune factors in females than in males. Acute stress increased microglia-associated transcripts in BLA in males, whereas chronic stress altered immune factor expression in BLA more broadly in females. In DHC, chronic stress increased immune factor expression in males but not females. Moreover, acute and chronic stress differentially affected microglial morphological activation state in male and female rats across all brain regions investigated. In males, chronic stress altered microglial activation in a pattern consistent with microglial involvement in stress

  13. Magnesium sulfate differentially modulates fetal membrane inflammation in a time-dependent manner.

    Cross, Sarah N; Nelson, Rachel A; Potter, Julie A; Norwitz, Errol R; Abrahams, Vikki M

    2018-04-30

    Chorioamnionitis and infection-associated inflammation are major causes of preterm birth. Magnesium sulfate (MgSO 4 ) is widely used in obstetrics as a tocolytic; however, its mechanism of action is unclear. This study sought to investigate how MgSO 4 modulates infection-associated inflammation in fetal membranes (FMs), and whether the response was time dependent. Human FM explants were treated with or without bacterial lipopolysaccharide (LPS); with or without MgSO 4 added either: 1 hour before LPS; at the same time as LPS; 1 hour post-LPS; or 2 hours post-LPS. Explants were also treated with or without viral dsRNA and LPS, alone or in combination; and MgSO 4 added 1 hour post-LPS After 24 hours, supernatants were measured for cytokines/chemokines; and tissue lysates measured for caspase-1 activity. Lipopolysaccharide-induced FM inflammation by upregulating the secretion of a number of inflammatory cytokines/chemokines. Magnesium sulfate administered 1-hour post-LPS inhibited FM secretion of IL-1β, IL-6, G-CSF, RANTES, and TNFα. Magnesium sulfate administered 2 hours post-LPS augmented FM secretion of these factors as well as IL-8, IFNγ, VEGF, GROα and IP-10. Magnesium sulfate delivered 1- hour post-LPS inhibited LPS-induced caspase-1 activity, and inhibited the augmented IL-1β response triggered by combination viral dsRNA and LPS. Magnesium sulfate differentially modulates LPS-induced FM inflammation in a time-dependent manner, in part through its modulation of caspase-1 activity. Thus, the timing of MgSO 4 administration may be critical in optimizing its anti-inflammatory effects in the clinical setting. MgSO 4 might also be useful at preventing FM inflammation triggered by a polymicrobial viral-bacterial infection. © 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Behavioral stress alters corticolimbic microglia in a sex- and brain region-specific manner

    Bollinger, Justin L.; Collins, Kaitlyn E.; Patel, Rushi

    2017-01-01

    Women are more susceptible to numerous stress-linked psychological disorders (e.g., depression) characterized by dysfunction of corticolimbic brain regions critical for emotion regulation and cognitive function. Although sparsely investigated, a number of studies indicate sex differences in stress effects on neuronal structure, function, and behaviors associated with these regions. We recently demonstrated a basal sex difference in- and differential effects of stress on- microglial activation in medial prefrontal cortex (mPFC). The resident immune cells of the brain, microglia are implicated in synaptic and dendritic plasticity, and cognitive-behavioral function. Here, we examined the effects of acute (3h/day, 1 day) and chronic (3h/day, 10 days) restraint stress on microglial density and morphology, as well as immune factor expression in orbitofrontal cortex (OFC), basolateral amygdala (BLA), and dorsal hippocampus (DHC) in male and female rats. Microglia were visualized, classified based on their morphology, and stereologically counted. Microglia-associated transcripts (CD40, iNOS, Arg1, CX3CL1, CX3CR1, CD200, and CD200R) were assessed in brain punches from each region. Expression of genes linked with cellular stress, neuroimmune state, and neuron-microglia communication varied between unstressed male and female rats in a region-specific manner. In OFC, chronic stress upregulated a wider variety of immune factors in females than in males. Acute stress increased microglia-associated transcripts in BLA in males, whereas chronic stress altered immune factor expression in BLA more broadly in females. In DHC, chronic stress increased immune factor expression in males but not females. Moreover, acute and chronic stress differentially affected microglial morphological activation state in male and female rats across all brain regions investigated. In males, chronic stress altered microglial activation in a pattern consistent with microglial involvement in stress

  15. Landscape Evolution Comparison between Sacra Mensa, Mars and the Grand Mesa, Colorado, USA

    Chesnutt, J. M.; Wegmann, K. W.; Cole, R. D.; Byrne, P. K.

    2017-12-01

    The Grand Mesa in Colorado is one of the largest and highest flat-topped mountains on Earth, and as such provides a compelling analog for Mars' Sacra Mensa. Both basalt-capped landforms are morphologically similar, enabling a landscape evolution comparison between the two that considers key differences in locale, composition, and environmental conditions. Sacra Mensa is nearly 50 times the area of Grand Mesa and towers 3 km above the surrounding area. The 1,300 km2 Grand Mesa rises 2 km above Grand Valley, and is bracketed by the Colorado and Gunnison Rivers in much the same way as Sacra Mensa is bounded by braided channels of Kasei Valles. The sustained incision by the Gunnison and Colorado was a key erosive force in the creation of the Grand Mesa, whereas punctuated but voluminous Hesperian glacio-fluvial floods are thought to have carved the Sacra Mensa. The Grand Mesa is undergoing extensive mass wasting, ranging from deadly landslides like the 2014 West Salt Creek rock avalanche to hundreds of slower-moving retrogressive slump blocks calving off the Miocene basalt cap. The genesis and modification of both landforms includes volcanic and fluvial activity, albeit in an inverted sequence. The Grand Mesa basalt cap has preserved the landform during the incision around its sides, whereas Sacra Mensa was likely carved by floods, with those flood channels later modified by lava flows. Recent (2015-2017) LiDAR surveys revealed massive and possible ancient landslides in many stream valleys and extensive earthflows on all sides of the Grand Mesa. In the case of the Grand Mesa, the large landslides are mainly occurring in one stratigraphic unit. In comparison, the western half of Sacra Mensa contains substantial slumping accompanied by landslides and debris flows, whereas the eastern half has relatively few such phenomena. Here, we report on the first Mesa-Mensa landscape evolution analog study. The surficial and bedrock mapping and 14C dating of key features of the

  16. GestuRe and ACtion Exemplar (GRACE) video database: stimuli for research on manners of human locomotion and iconic gestures.

    Aussems, Suzanne; Kwok, Natasha; Kita, Sotaro

    2018-06-01

    Human locomotion is a fundamental class of events, and manners of locomotion (e.g., how the limbs are used to achieve a change of location) are commonly encoded in language and gesture. To our knowledge, there is no openly accessible database containing normed human locomotion stimuli. Therefore, we introduce the GestuRe and ACtion Exemplar (GRACE) video database, which contains 676 videos of actors performing novel manners of human locomotion (i.e., moving from one location to another in an unusual manner) and videos of a female actor producing iconic gestures that represent these actions. The usefulness of the database was demonstrated across four norming experiments. First, our database contains clear matches and mismatches between iconic gesture videos and action videos. Second, the male actors and female actors whose action videos matched the gestures in the best possible way, perform the same actions in very similar manners and different actions in highly distinct manners. Third, all the actions in the database are distinct from each other. Fourth, adult native English speakers were unable to describe the 26 different actions concisely, indicating that the actions are unusual. This normed stimuli set is useful for experimental psychologists working in the language, gesture, visual perception, categorization, memory, and other related domains.

  17. Relations of Brand Image Tocustomers Buying Decisionon Grand Inna Muara Hotel Padang

    Zengga, Zengga; Chair, Ira Meirina; Abrian, Youmil

    2013-01-01

    This study aims to describe the relations between brand image to customers buying decision room in hotel grand inna muara padang. This study is a descriptive correlational study. The study population as many as 1694 consists of guest during stay on grand inna muara hotel padang. The descriptive analysis of the results showed that brand image categorized excellent (56%) and categorized quite good (33%). The descriptive analysis of the result results showed that customers buying decision categ...

  18. Herpetofauna of Núcleo Experimental de Iguaba Grande, Rio de Janeiro state, Brazil

    Martins, AR; Bruno, SF.; Navegantes, AQ.

    2012-01-01

    The Atlantic Rain forest, which is considered the second largest pluvial forest in the American continent, has had an estimated 93% of its original area destroyed. Although studies concerning the herpetofaunal diversity in this biome have been intensified in the past years, its diversity is still underestimated. The Nucleo Experimental de Iguaba Grande (NEIG) is included in an Environmental Protection Area (APA de Sapeatiba) in the Iguaba Grande municipality, Rio de Janeiro state, Brazil (22º...

  19. Pengaruh Experiential Marketing Dan Brand Trust Terhadap Kepuasan Konsumen Dan Loyalitas Pelanggan Hotel Grand Jatra Pekanbaru

    Yufizar, Adithya Fajar; Restuti, Sri; Rahayu, Deny Danar

    2017-01-01

    This research aimed to analyze Experiential Marketing, Brand Trust on Customer Satisfaction and Customer Loyalty, research applied on customer Grand Jatra Hotel in Pekanbaru City. The object of this research was Customer Grand Jatra Hotel in Pekanbaru City. This research consists of four variables: the dependent variable, one intervening variable and two independent variables. They are Customer Loyalty(Y2), Customer Satisfaction (Y1), Brand Trust (X2), and Experintial Marketing (X1). This res...

  20. MIdentidade de classe : um olhar sobre os estivadores do porto do Rio Grande/RS

    Thiago Cedrez da Silva

    2015-06-01

    Full Text Available This article aims to understand the identity notion that permeates the charaxter of the docker of the Port of Rio Grande / RS in its work universe. Starting from the theoretical framework of class identity, the reflection of documental and oral sources, as well as the existing literature on this subject, the profile of the docker of Rio Grande, between 1931 and 1960, will be analyzed.