WorldWideScience

Sample records for gpr gas pipe

  1. A LOW-COST GPR GAS PIPE & LEAK DETECTOR

    Energy Technology Data Exchange (ETDEWEB)

    David Cist; Alan Schutz

    2005-03-30

    A light-weight, easy to use ground penetrating radar (GPR) system for tracking metal/non-metal pipes has been developed. A pre-production prototype instrument has been developed whose production cost and ease of use should fit important market niches. It is a portable tool which is swept back and forth like a metal detector and which indicates when it goes over a target (metal, plastic, concrete, etc.) and how deep it is. The innovation of real time target detection frees the user from having to interpret geophysical data and instead presents targets as dots on the screen. Target depth is also interpreted automatically, relieving the user of having to do migration analysis. In this way the user can simply walk around looking for targets and, by ''connecting the dots'' on the GPS screen, locate and follow pipes in real time. This is the first tool known to locate metal and non-metal pipes in real time and map their location. This prototype design is similar to a metal detector one might use at the beach since it involves sliding a lightweight antenna back and forth over the ground surface. The antenna is affixed to the end of an extension that is either clipped to or held by the user. This allows him to walk around in any direction, either looking for or following pipes with the antenna location being constantly recorded by the positioning system. Once a target appears on the screen, the user can locate by swinging the unit to align the cursor over the dot. Leak detection was also a central part of this project, and although much effort was invested into its development, conclusive results are not available at the time of the writing of this document. Details of the efforts that were made as a part of this cooperative agreement are presented.

  2. Pipe-flange detection with GPR

    International Nuclear Information System (INIS)

    Bonomo, Néstor; De la Vega, Matías; Martinelli, Patricia; Osella, Ana

    2011-01-01

    This paper describes an application of the ground penetrating radar (GPR) method for detecting pipe flanges. A case history is described in which GPR was successfully used to locate pipe flanges along an 8 km metal pipeline, using a fixed-offset methodology, from the ground surface. Summaries of numerical simulations and in situ tests, performed before the definitive prospecting to evaluate the feasibility of detection, are included. Typical GPR signals are analysed and several examples shown. Constant-time sections of data volumes and migration are evaluated with the goal of distinguishing flange signals from rock signals in unclear situations. The applied methodology was effective for detecting the pipe flanges in relatively short times, with accuracies below 10 cm in the horizontal direction and 20 cm in the vertical direction

  3. Analysis of the Gas Particle Radiator (GPR)

    Science.gov (United States)

    Chubb, D. L.

    1986-01-01

    The theoretical performance of a new space radiator concept, the gas particle radiator (GPR), is calculated. The GPR uses a gas containing emitting, submicron particles as the radiating media. A transparent window contains the gas particle mixture around the solid radiator emitting surface. A major advantage of the GPR is that large emissivity (e sub T is greater than or = 0.8) is achieved without the use of emissive coatings. A radiation heat transfer analysis shows that for a modest volume fraction (approx. 10(-4)) of submicron particles and gas thickness (approx. 1 cm) the emissivity, e sub T, is limited by the window transmittance. Besides determining the emissivity, the window is the critical element for making it possible for the GPR to have lower mass than a tube type radiator. The window acts as a bumper to provide meteoroid protection for the radiator wall. The GPR was compared to a proposed titanium wall, potassium heat pipe radiator. For both radiators operating at a power level of 1.01 MW at 775 K it was calculated that the GPR mass was 31 percent lower than the heat pipe radiator.

  4. 3D FDTD modelling of GPR: the effects of antenna polarisation on gpr signals from nonmetal pipes

    International Nuclear Information System (INIS)

    Amiruddin Shaari

    2003-01-01

    A 3D finite-difference time domain (FDTD) modelling of ground penetrating radar (GPR) has been carried out in order to determine the effectiveness of the method when it is used in a ground survey for metal and nonmetal pipes. In particular, the effects of the relative orientation between the antenna polarisation and pipe length and the dielectric contrast between ground soil and pipes on the GPR signal strength are investigated. The results show that the parallel antenna-target is the preferred orientation for metal pipes while the normal or orthogonal arrangement is the preferred one for the nonmetal pipes. The dielectric contrast between medium and target also seems to affect the strength the GPR signals from the nines. (Author)

  5. Location of buried plastic pipes using multi-agent support based on GPR images

    Science.gov (United States)

    Ayala-Cabrera, David; Herrera, Manuel; Izquierdo, Joaquín; Pérez-García, Rafael

    2011-12-01

    This work focuses on the generation of tools to aid inspection and identify buried plastic pipes in water supply systems (WSS). In our study we use ground penetrating system (GPR) images as a non-destructive method of obtaining information without altering the system conditions and the environmental characteristics. A viability study for extracting features, and an approach to the above-mentioned application based on multi-agent systems are addressed in this paper. Firstly, we use intensive matrix manipulation of the GPR output for preprocessing the images. As a result, two matrices are produced that classify initial data based on the original radargram of the wave amplitude parameter. Then the plastic pipe characteristics that offer an enhanced likelihood of location are defined. This procedure is evaluated through two case-studies. One study corresponds to a simple case (one pipe) and the other corresponds to various pipes (made of different materials). Both cases were developed under controlled laboratory conditions. The obtained results are promising, and we show that automatic plastic pipe location has been achieved. The main contributions of the procedures proposed in this work are: firstly, highly skilled GPR prospection operators become unnecessary for plastic pipe location using GPR images; and secondly, we have opened a route to further classification that makes use of other methodologies.

  6. Spinning pipe gas lens revisited

    CSIR Research Space (South Africa)

    Mafusire, C

    2008-01-01

    Full Text Available , there is little information on optical phase aberrations and no study to date on the propagation parameters of the laser beam, but has rather remained rooted in the domain of ray optics. Researchers revisit the spinning pipe gas lens in this paper with new...

  7. Gas lensing in a heated spinning pipe

    CSIR Research Space (South Africa)

    Mafusire, C

    2006-07-01

    Full Text Available When a heated pipe is rotated, the dynamics of the gas inside exhibit properties reminiscent of a solid-state positive lens. The properties are a result of a parabolic distribution of refractive index in the pipe which is caused by mixing of hot...

  8. 46 CFR 154.910 - Inert gas piping: Location.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Inert gas piping: Location. 154.910 Section 154.910 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY... Atmospheric Control in Cargo Containment Systems § 154.910 Inert gas piping: Location. Inert gas piping must...

  9. Venting of gas deflagrations through relief pipes

    OpenAIRE

    Ferrara, Gabriele

    2006-01-01

    Vent devices for gas and dust explosions are often ducted to safety locations by means of relief pipes for the discharge of hot combustion products or blast waves (NFPA 68, 2002). The presence of the duct is likely to increase the severity of the explosion with respect to simply vented vessels posing a problem for the proper design of this venting configuration. The phenomenology of the vented explosion is complicated as the interaction of combustion in the duct with primary combustion in...

  10. CFD model of a spinning pipe gas lens

    CSIR Research Space (South Africa)

    Snedden, Glen C

    2006-07-01

    Full Text Available Slides on: Spinning Pipe Gas Lens; Focal Length; Refractive Index; Gas Dynamics; Guess at the gas dynamics; Density Profile; Flow Profile; Rosby Waves; Rayleigh–Taylor Instabilities...

  11. GPR image analysis to locate water leaks from buried pipes by applying variance filters

    Science.gov (United States)

    Ocaña-Levario, Silvia J.; Carreño-Alvarado, Elizabeth P.; Ayala-Cabrera, David; Izquierdo, Joaquín

    2018-05-01

    Nowadays, there is growing interest in controlling and reducing the amount of water lost through leakage in water supply systems (WSSs). Leakage is, in fact, one of the biggest problems faced by the managers of these utilities. This work addresses the problem of leakage in WSSs by using GPR (Ground Penetrating Radar) as a non-destructive method. The main objective is to identify and extract features from GPR images such as leaks and components in a controlled laboratory condition by a methodology based on second order statistical parameters and, using the obtained features, to create 3D models that allows quick visualization of components and leaks in WSSs from GPR image analysis and subsequent interpretation. This methodology has been used before in other fields and provided promising results. The results obtained with the proposed methodology are presented, analyzed, interpreted and compared with the results obtained by using a well-established multi-agent based methodology. These results show that the variance filter is capable of highlighting the characteristics of components and anomalies, in an intuitive manner, which can be identified by non-highly qualified personnel, using the 3D models we develop. This research intends to pave the way towards future intelligent detection systems that enable the automatic detection of leaks in WSSs.

  12. Noncondensable gas accumulation phenomena in nuclear power plant piping

    International Nuclear Information System (INIS)

    Yamamoto, Yasushi; Aoki, Kazuyoshi; Sato, Teruaki; Shida, Akira; Ichikawa, Nagayoshi; Nishikawa, Akira; Inagaki, Tetsuhiko

    2011-01-01

    In the case of the boiling water reactor, hydrogen and oxygen slightly exist in the main steam, because these noncondensable gases are generated by the radiolytic decomposition of the reactor water. BWR plants have taken measures to prevent noncondensable gas accumulation. However, in 2001, the detonation of noncondensable gases occurred at Hamaoka-1 and Brunsbuttel, resulting in ruptured piping. The accumulation phenomena of noncondensable gases in BWR closed piping must be investigated and understood in order to prevent similar events from occurring in the future. Therefore, an experimental study on noncondensable gas accumulation was carried out. The piping geometries for testing were classified and modeled after the piping of actual BWR plants. The test results showed that 1) noncondensable gases accumulate in vertical piping, 2) it is hard for noncondensable gases to accumulate in horizontal piping, and 3) noncondensable gases accumulate under low-pressure conditions. A simple accumulation analysis method was proposed. To evaluate noncondensable gas accumulation phenomena, the three component gases were treated as a mixture. It was assumed that the condensation amount of the vapor is small, because the piping is certainly wrapped with heat insulation material. Moreover, local thermal equilibrium was assumed. This analysis method was verified using the noncondensable gas accumulation test data on branch piping with a closed top. Moreover, an experimental study on drain trap piping was carried out. The test results showed that the noncondensable gases dissolved in the drain water were discharged from the drain trap, and Henry's law could be applied to evaluate the amount of dissolved noncondensable gases in the drain water. (author)

  13. Startup analysis for a high temperature gas loaded heat pipe

    Science.gov (United States)

    Sockol, P. M.

    1973-01-01

    A model for the rapid startup of a high-temperature gas-loaded heat pipe is presented. A two-dimensional diffusion analysis is used to determine the rate of energy transport by the vapor between the hot and cold zones of the pipe. The vapor transport rate is then incorporated in a simple thermal model of the startup of a radiation-cooled heat pipe. Numerical results for an argon-lithium system show that radial diffusion to the cold wall can produce large vapor flow rates during a rapid startup. The results also show that startup is not initiated until the vapor pressure p sub v in the hot zone reaches a precise value proportional to the initial gas pressure p sub i. Through proper choice of p sub i, startup can be delayed until p sub v is large enough to support a heat-transfer rate sufficient to overcome a thermal load on the heat pipe.

  14. Non-invasive characterization of biogenic gas dynamics in peatlands using the ground penetrating radar (GPR) method

    Science.gov (United States)

    Comas, X.; Slater, L. D.; Reeve, A. S.; Glaser, P. H.; Nolan, J. T.; Parsekian, A.

    2009-12-01

    Several applications of ground penetrating radar (GPR) as a non-invasive technology for investigating carbon cycling in northern peatlands are presented here. The GPR method has been proved as an effective approach for investigating biogenic gas dynamics over a wide range of spatial scales. Unlike other commonly applied techniques used in peatland science, GPR can be employed entirely non-invasively from the surface, and therefore can provide information on the vertical distribution of biogenic gases within the peat structure without disruption to the in situ gas regime. Several applications of the GPR method in peatlands research are presented here and include: (1) imaging of laterally continuous woody layers that may act as confining layers for free phase gas (FPG) accumulation as proposed by others; (2) surface and cross-hole measurements to estimate one-dimensional vertical profiles of variable FPG content and confirm accumulation of FPG below confining layers; (3) non-invasive time-lapse monitoring of FPG production and emissions from a peat column and use of reflection amplitudes to show that, in addition to travel times, amplitude analysis can also yield insights into changes in FPG production and emissions (e.g. via ebullition) from peat soils. We conclude with some further recommendations for future applications of GPR in northern peatlands.

  15. Residual lifetime assessment of uPVC gas pipes

    OpenAIRE

    Visser, HA

    2010-01-01

    The Dutch gas distribution network consists of about 20% (22,500 km) of unplasticised poly(vinyl chloride) (uPVC) pipes, most of which have been installed from the mid-sixties up to the mid-seventies of the previous century and have been in service ever since. Replacing the uPVC gas pipes exactly after the specified service lifetime of 50 years will lead to a costly and extremely labour intensive project in the next decade. Postponing the replacement is only an option when it can be done with...

  16. Optical turbulence in a spinning pipe gas lens

    CSIR Research Space (South Africa)

    Mafusire, C

    2009-07-01

    Full Text Available The researchers have managed to do quantitative analysis of ‘controlled’ turbulence. The researchers could control the degree of turbulence by controlling the rotation speed and wall temperature of the spinning pipe gas lens. The researchers also...

  17. Wave aberrations in a spinning pipe gas lens

    CSIR Research Space (South Africa)

    Mafusire, C

    2009-06-01

    Full Text Available The graded index (GRIN-like) medium generated by a gas inside a heated pipe when it is rotated about its longitudinal axis has the ability to focus a laser beam. However, recent research has shown that the medium generated has a deleterious effect...

  18. A study of stratified gas-liquid pipe flow

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, George W.

    2005-07-01

    This work includes both theoretical modelling and experimental observations which are relevant to the design of gas condensate transport lines. Multicomponent hydrocarbon gas mixtures are transported in pipes over long distances and at various inclinations. Under certain circumstances, the heavier hydrocarbon components and/or water vapour condense to form one or more liquid phases. Near the desired capacity, the liquid condensate and water is efficiently transported in the form of a stratified flow with a droplet field. During operating conditions however, the flow rate may be reduced allowing liquid accumulation which can create serious operational problems due to large amounts of excess liquid being expelled into the receiving facilities during production ramp-up or even in steady production in severe cases. In particular, liquid tends to accumulate in upward inclined sections due to insufficient drag on the liquid from the gas. To optimize the transport of gas condensates, a pipe diameters should be carefully chosen to account for varying flow rates and pressure levels which are determined through the knowledge of the multiphase flow present. It is desirable to have a reliable numerical simulation tool to predict liquid accumulation for various flow rates, pipe diameters and pressure levels which is not presently accounted for by industrial flow codes. A critical feature of the simulation code would include the ability to predict the transition from small liquid accumulation at high flow rates to large liquid accumulation at low flow rates. A semi-intermittent flow regime of roll waves alternating with a partly backward flowing liquid film has been observed experimentally to occur for a range of gas flow rates. Most of the liquid is transported in the roll waves. The roll wave regime is not well understood and requires fundamental modelling and experimental research. The lack of reliable models for this regime leads to inaccurate prediction of the onset of

  19. ACOUSTIC DETECTING AND LOCATING GAS PIPE LINE INFRINGEMENT

    Energy Technology Data Exchange (ETDEWEB)

    John L. Loth; Gary J. Morris; George M. Palmer; Richard Guiler; Patrick Browning

    2004-12-01

    The extensive network of high-pressure natural gas transmission pipelines covering the United States provides an important infrastructure for our energy independence. Early detection of pipeline leaks and infringements by construction equipment, resulting in corrosion fractures, presents an important aspect of our national security policy. The National Energy Technology Laboratory Strategic Center for Natural Gas (SCVG) is and has been funding research on various applicable techniques. The WVU research team has focused on monitoring pipeline background acoustic signals generated and transmitted by gas flowing through the gas inside the pipeline. In case of a pipeline infringement, any mechanical impact on the pipe wall, or escape of high-pressure gas, generates acoustic signals traveling both up and down stream through the gas. Sudden changes in flow noise are detectable with a Portable Acoustic Monitoring Package (PAMP), developed under this contract. It incorporates a pressure compensating microphone and a signal- recording device. Direct access to the gas inside the line is obtained by mounting such a PAMP, with a 1/2 inch NPT connection, to a pipeline pressure port found near most shut-off valves. An FFT of the recorded signal subtracted by that of the background noise recorded one-second earlier appears to sufficiently isolate the infringement signal to allow source interpretation. Using cell phones for data downloading might allow a network of such 1000-psi rated PAMP's to acoustically monitor a pipeline system and be trained by neural network software to positively identify and locate any pipeline infringement.

  20. ACOUSTIC DETECTING AND LOCATING GAS PIPE LINE INFRINGEMENT

    Energy Technology Data Exchange (ETDEWEB)

    John L. Loth; Gary J. Morris; George M. Palmer; Richard Guiler; Patrick Browning

    2004-10-31

    The extensive network of high-pressure natural gas transmission pipelines covering the United States provides an important infrastructure for our energy independence. Early detection of pipeline leaks and infringements by construction equipment, resulting in corrosion fractures, presents an important aspect of our national security policy. The National Energy Technology Laboratory Strategic Center for Natural Gas (SCVG) is and has been funding research on various applicable techniques. The WVU research team has focused on monitoring pipeline background acoustic signals generated and transmitted by gas flowing through the gas inside the pipeline. In case of a pipeline infringement, any mechanical impact on the pipe wall, or escape of high-pressure gas, generates acoustic signals traveling both up and down stream through the gas. Sudden changes in flow noise are detectable with a Portable Acoustic Monitoring Package (PAMP), developed under this contract. It incorporates a pressure compensating microphone and a signal- recording device. Direct access to the gas inside the line is obtained by mounting such a PAMP, with a 1/2 inch NPT connection, to a pipeline pressure port found near most shut-off valves. An FFT of the recorded signal subtracted by that of the background noise recorded one-second earlier appears to sufficiently isolate the infringement signal to allow source interpretation. Using cell phones for data downloading might allow a network of such 1000-psi rated PAMP's to acoustically monitor a pipeline system and be trained by neural network software to positively identify and locate any pipeline infringement.

  1. Numerical simulation for gas-liquid two-phase flow in pipe networks

    International Nuclear Information System (INIS)

    Li Xiaoyan; Kuang Bo; Zhou Guoliang; Xu Jijun

    1998-01-01

    The complex pipe network characters can not directly presented in single phase flow, gas-liquid two phase flow pressure drop and void rate change model. Apply fluid network theory and computer numerical simulation technology to phase flow pipe networks carried out simulate and compute. Simulate result shows that flow resistance distribution is non-linear in two phase pipe network

  2. Film behaviour of vertical gas-liquid flow in a large diameter pipe

    OpenAIRE

    Zangana, Mohammed Haseeb Sedeeq

    2011-01-01

    Gas-liquid flow commonly occurs in oil and gas production and processing system. Large diameter vertical pipes can reduce pressure drops and so minimize operating costs. However, there is a need for research on two-phase flow in large diameter pipes to provide confidence to designers of equipments such as deep water risers. In this study a number of experimental campaigns were carried out to measure pressure drop, liquid film thickness and wall shear in 127mm vertical pipe. Total pressur...

  3. Characterisation of a spinning pipe gas lens using a Shack–Hartmann wavefront sensor

    CSIR Research Space (South Africa)

    Mafusire, C

    2007-01-01

    Full Text Available A heated horizontal spinning pipe causes gases inside it to assume dynamics resulting in a graded index lens – a spinning pipe gas lens (SPGL). A CFD model is presented which shows that gas exchanges of the SPGL with the surroundings resulting in a...

  4. 76 FR 40717 - Transcontinental Gas Pipe Line Company, LLC; Notice of Intent To Prepare an Environmental...

    Science.gov (United States)

    2011-07-11

    .... Date and time Location Monday, July 18, 2011, 6 p.m. EDT. Hughesville Volunteer Fire Company, Social... Gas Pipe Line Company, LLC; Notice of Intent To Prepare an Environmental Assessment for the Planned... (Project) involving construction and operation of facilities by Transcontinental Gas Pipe Line Company, LLC...

  5. Fusion of two electromagnetic field sensor technologies for application to the location of buried gas pipes. Annual report No. 1, July 1, 1994-June 30, 1995

    Energy Technology Data Exchange (ETDEWEB)

    Tranbarger, O.; Fisher, J.L.; Beissner, R.E.; Zook, B.J.

    1995-07-31

    This report describes work accomplished in the first year of a project to develop a practical pipe locator tool for both plastic and metal pipe. Efforts in the first year focused on showing separately the feasibility of both the GPR and Eddy current (EC) technologies to locate pipes. The ground-penetrating radar (GPR) used for demonstration of feasibility was an FM-CW radar system operating the VHF and UHF ranges. In moderate-loss soils, images were produced on 4-inch polyethylene (PE) pipe down to three feet; 2-in PE pipe could be imaged to a depth of two feet. With the EC technology, the edges of backfilled pipe trenches are detectable, and plastic pipes could be detected at shallow depths in high conductivity soils.

  6. 46 CFR 61.15-10 - Liquefied-petroleum-gas piping for heating and cooking.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Liquefied-petroleum-gas piping for heating and cooking. 61.15-10 Section 61.15-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE... piping for heating and cooking. (a) Leak tests as described in paragraph (b) of this section shall be...

  7. One-Way Flow of a Rarefied Gas Induced in a Circular Pipe with a Periodic Temperature Distribution

    National Research Council Canada - National Science Library

    Aoki, K

    2000-01-01

    The steady behavior of a rarefied gas in a circular pipe with a saw-like temperature distribution increasing and decreasing periodically in the direction of the pipe axis is investigated numerically...

  8. Thermal Analysis of the Divertor Primary Heat Transfer System Piping During the Gas Baking Process

    Energy Technology Data Exchange (ETDEWEB)

    Yoder Jr, Graydon L [ORNL; Harvey, Karen [ORNL; Ferrada, Juan J [ORNL

    2011-02-01

    A preliminary analysis has been performed examining the temperature distribution in the Divertor Primary Heat Transfer System (PHTS) piping and the divertor itself during the gas baking process. During gas baking, it is required that the divertor reach a temperature of 350 C. Thermal losses in the piping and from the divertor itself require that the gas supply temperature be maintained above that temperature in order to ensure that all of the divertor components reach the required temperature. The analysis described in this report was conducted in order to estimate the required supply temperature from the gas heater.

  9. Severe slugging in gas-liquid two-phase pipe flow

    NARCIS (Netherlands)

    Malekzadeh, R.

    2012-01-01

    transportation facilities. In an offshore oil and gas production facility, pipeline-riser systems are required to transport two-phase hydrocarbons from subsurface oil and gas wells to a central production platform. Severe slugs reaching several thousands pipe diameters may occur when transporting

  10. Monitoring the evolution and migration of a methane gas plume in an unconfined sandy aquifer using time-lapse GPR and ERT

    Science.gov (United States)

    Steelman, Colby M.; Klazinga, Dylan R.; Cahill, Aaron G.; Endres, Anthony L.; Parker, Beth L.

    2017-10-01

    Fugitive methane (CH4) leakage associated with conventional and unconventional petroleum development (e.g., shale gas) may pose significant risks to shallow groundwater. While the potential threat of stray (CH4) gas in aquifers has been acknowledged, few studies have examined the nature of its migration and fate in a shallow groundwater flow system. This study examines the geophysical responses observed from surface during a 72 day field-scale simulated CH4 leak in an unconfined sandy aquifer at Canadian Forces Base Borden, Canada, to better understand the transient behaviour of fugitive CH4 gas in the subsurface. Time-lapse ground-penetrating radar (GPR) and electrical resistivity tomography (ERT) were used to monitor the distribution and migration of the gas-phase and assess any impacts to groundwater hydrochemistry. Geophysical measurements captured the transient formation of a CH4 gas plume emanating from the injector, which was accompanied by an increase in total dissolved gas pressure (PTDG). Subsequent reductions in PTDG were accompanied by reduced bulk resistivity around the injector along with an increase in the GPR reflectivity along horizontal bedding reflectors farther downgradient. Repeat temporal GPR reflection profiling identified three events with major peaks in reflectivity, interpreted to represent episodic lateral CH4 gas release events into the aquifer. Here, a gradual increase in PTDG near the injector caused a sudden lateral breakthrough of gas in the direction of groundwater flow, causing free-phase CH4 to migrate much farther than anticipated based on groundwater advection. CH4 accumulated along subtle permeability boundaries demarcated by grain-scale bedding within the aquifer characteristic of numerous Borden-aquifer multi-phase flow experiments. Diminishing reflectivity over a period of days to weeks suggests buoyancy-driven migration to the vadose zone and/or CH4 dissolution into groundwater. Lateral and vertical CH4 migration was

  11. Market study of pipe gas for the Bahia State, Brazil

    International Nuclear Information System (INIS)

    1992-09-01

    The energy market that will be conquered by the natural gas in Bahia State is identified, allowing measure the potentiality of gas industry and the gas supply, that the State will plead to the Federal Government. (C.G.C.)

  12. Non-invasive Investigation of Free Phase Gas Accumulation in a Northern Peatland Using GPR: Vegetation Effects

    Science.gov (United States)

    Parsekian, A.; Nolan, J.; Comas, X.; Slater, L.

    2008-05-01

    Northern peatlands are known to produce methane, although the contribution of this source to the atmospheric methane burden is still uncertain. Biogenic methane releases have become an increasingly important issue with regard to assessing the impact of northern peatlands impact on the global carbon budget. Previous workers have suggested that methane production is pronounced in a zone a few meters below the surface and that accumulation of free phase gas is encouraged by the presence of confining layers that act to hinder FPG release. We used ground penetrating radar (GPR) to non-invasively investigate (1) where free-phase gas (FPG) methane may be accumulating vertically within the peat column of a northern peatland, and (2) the dependence of methane production on vegetation type. Common mid-point (CMP) measurements were applied to investigate the likely vertical spatial distribution/ concentration of trapped methane within the peat profile within different vegetation units. The CMP data were modeled using the Complex Refractive Index Model (CRIM) to obtain a one dimensional model of interval layer velocities presumably representing the vertical distribution of gas content. CMP surveys were conducted at several locations in Caribou Bog peatland (Orono, Maine) in order to assess how peat thickness and surface vegetation communities may be impact FPG accumulation in the sub-surface. These locations include an open pool system, a low shrub heath area and a densely forested zone. As well as having variable surface vegetation communities, the total peat thickness is distinctly different at each of these sites. Preliminary results suggest that the CMP models are distinctly different between these sites and suggest a dependence of FPG accumulation on vegetation type.

  13. GPR120

    DEFF Research Database (Denmark)

    Gao, B.; Huang, Q.; Jie, Q.

    2015-01-01

    /2 cascade, while low concentrations elevated P38 and increased adipogenesis. The fine molecular regulation of GPR120 was implemented by up-regulating different integrin subunits (alpha 1, alpha 2 and beta 1; alpha 5 and beta 3). The administration of high doses of TUG-891 rescued oestrogen-deficient bone...... was involved in the cytoplasmic regulation of a seesaw-like balance between ERK and p38 phosphorylation. These findings provide new hope for developing novel remedies to treat osteoporosis by adjusting the GPR120-mediated differentiation balance of BMMSCs....

  14. Formation of Sclerotic Hydrate Deposits in a Pipe for Extraction of a Gas from a Dome Separator

    Science.gov (United States)

    Urazov, R. R.; Chiglinstev, I. A.; Nasyrov, A. A.

    2017-09-01

    The theory of formation of hydrate deposits on the walls of a pipe for extraction of a gas from a dome separator designed for the accident-related collection of hydrocarbons on the ocean floor is considered. A mathematical model has been constructed for definition of a steady movement of a gas in such a pipe with gas-hydrate deposition under the conditions of changes in the velocity, temperature, pressure, and moisture content of the gas flow.

  15. The Effect of Gas Kinetics on the Gas-Lift Efficiency for Viscous Oil in Vertical Pipe Flow

    OpenAIRE

    Steinbakk, Carina Hoddø

    2015-01-01

    For heavy oil, artificial lift can be applied to increase and stabilise production flow. How the gas kinetics, i.e. the lift-gas composition will influence this increase is the subject of this thesis and will be described in relation to multiphase flow, pressure drop and pressure-temperature-volume (PVT) -theory. A vertical pipe flow was studied, simulating the pressure drop coupled with the accompanying multiphase flow and PVT-information. The simulations were run in MATLAB, supported by...

  16. 77 FR 55208 - Transcontinental Gas Pipe Line Company, LLC; Notice of Intent To Prepare an Environmental...

    Science.gov (United States)

    2012-09-07

    .... You must wait until the Commission receives a formal application for the Project. Additional...] Transcontinental Gas Pipe Line Company, LLC; Notice of Intent To Prepare an Environmental Assessment for the Planned Virginia Southside Expansion Project; Request for Comments on Environmental Issues and Notice of...

  17. 75 FR 42738 - Transcontinental Gas Pipe Line Company, LLC; Notice of Intent To Prepare an Environmental...

    Science.gov (United States)

    2010-07-22

    ... must wait until a formal application for the project is filed with the Commission. Additional...] Transcontinental Gas Pipe Line Company, LLC; Notice of Intent To Prepare an Environmental Assessment for the Planned Mid-Atlantic Connector Expansion Project, Request for Comments on Environmental Issues, and Notice...

  18. 75 FR 51455 - Transcontinental Gas Pipe Line Company, LLC; Notice of Intent To Prepare an Environmental...

    Science.gov (United States)

    2010-08-20

    ... must wait until a formal application for the project is filed with the Commission. Additional...] Transcontinental Gas Pipe Line Company, LLC; Notice of Intent To Prepare an Environmental Assessment for the Planned Mid-South Expansion Project and Request for Comments on Environmental Issues August 13, 2010. The...

  19. Rejection of seamless pipe noise in magnetic flux leakage data obtained from gas pipeline inspection

    Science.gov (United States)

    Afzal, Muhammad; Udpa, Satish; Udpa, Lalita; Lord, William

    2000-05-01

    Natural gas is traditionally transmitted from production facilities to customer locations through a vast pipeline network. A major segment of this network employs seamless pipes. This is especially true for smaller diameter transmission and distribution lines. Manufacturing process associated with the production of seamless pipes contribute to a helical variation in the pipe along the axis. The deformation introduces an artifact in the data obtained from MFL inspection of these pipelines. This seamless pipe noise is usually correlated with signals generated by defects and other elements (joints, tees, etc.) in pipelines, and can therefore, mask their indications in MFL data. This warrants the need for methods to improve signal-to-noise ratio (SNR) in MFL data from seamless pipes. This paper presents a technique for detecting signals in MFL data from seamless pipes. The approach processes the data in various steps. First, a wavelet based denoising technique is applied to reduce the noise due to instrumentation and other sources. An adaptive filtering approach is then applied to reject seamless noise in the data. Since the inspection of pipelines typically generates vast amounts of data, it is imperative that the algorithm be computationally efficient. The processing method has to be robust in that it should be data independent. The approach described in this paper meet these criteria. Results from application of the approach to data from field tests are presented.

  20. Study on heat pipe assisted thermoelectric power generation system from exhaust gas

    Science.gov (United States)

    Chi, Ri-Guang; Park, Jong-Chan; Rhi, Seok-Ho; Lee, Kye-Bock

    2017-11-01

    Currently, most fuel consumed by vehicles is released to the environment as thermal energy through the exhaust pipe. Environmentally friendly vehicle technology needs new methods to increase the recycling efficiency of waste exhaust thermal energy. The present study investigated how to improve the maximum power output of a TEG (Thermoelectric generator) system assisted with a heat pipe. Conventionally, the driving energy efficiency of an internal combustion engine is approximately less than 35%. TEG with Seebeck elements is a new idea for recycling waste exhaust heat energy. The TEG system can efficiently utilize low temperature waste heat, such as industrial waste heat and solar energy. In addition, the heat pipe can transfer heat from the automobile's exhaust gas to a TEG. To improve the efficiency of the thermal power generation system with a heat pipe, effects of various parameters, such as inclination angle, charged amount of the heat pipe, condenser temperature, and size of the TEM (thermoelectric element), were investigated. Experimental studies, CFD simulation, and the theoretical approach to thermoelectric modules were carried out, and the TEG system with heat pipe (15-20% charged, 20°-30° inclined configuration) showed the best performance.

  1. Experiments in stratified gas-liquid pipe flow

    NARCIS (Netherlands)

    Birvalski, M.

    2015-01-01

    The growing demand for energy in the future will necessitate the production of natural gas from fields which are located farther offshore, in deep water and in very cold environments. This will confront us with difficulties in ensuring continuous production of the fluids (natural gas, condensate and

  2. Phenomena and Detection of Gas Accumulation in Piping Systems

    International Nuclear Information System (INIS)

    Lee, D. Y.; Jeon, S. S.; Hong, S. J.; Song, Y. J.

    2011-01-01

    U.S. Nuclear Regulatory Commission (NRC) issued Generic Letter (GL) 2008-01 which provides recommendation and guidance to nuclear power plants for managing gas intrusion and accumulation in safety systems such as Emergency Core Cooling (ECC), Decay Heat Removal (DHR) and Containment Spray (CS) systems. Following the GL2008-01, Nuclear Energy Institute (NEI) reported NEI 09-10 that gives industry guidance for effective prevention and management of system gas accumulation. All of U.S. utilities responded to the GL2008-01 with evaluation results for gas accumulation in safety systems mentioned above. This paper summarizes key phenomena to be evaluated against gas accumulation in safety systems and detection methods for gas accumulation in subjected systems

  3. Suggestions to leak prevention in Fortaleza's natural gas piping system; Sugestoes para a prevencao de vazamentos de gas natural canalizado na regiao metropolitana de Fortaleza

    Energy Technology Data Exchange (ETDEWEB)

    Teles, Marcus de Barros [Agencia Reguladora de Servicos Publicos Delegados do Estado do Ceara (ARCE), Fortaleza, CE (Brazil)

    2004-07-01

    Leaks are the bigger problem in health, safety and environmental when the subject is gas distribution piping systems. Specially in high density human regions, like in the majority districts of Fortaleza, safety have to be the higher priority to the gas company responsible for the gas distribution piping systems. Leaks are able to cause accidents or incidents, depending on the circumstances which they happen. In order to be control the situation and overcome the luck factor, leaks must be previously avoided by the application of some security requirements. This paper present some suggestions to natural gas leak prevention in the Fortaleza's metropolitan region pipeline systems. First, the piping systems are analysed, observing the risk regions. Then, safety actions and basic requirements to avoid pipe corrosion are presented in order to improve safety in the gas distribution piping systems of Fortaleza's metropolitan region. (author)

  4. 24 CFR 3280.705 - Gas piping systems.

    Science.gov (United States)

    2010-04-01

    ... following information using letters no smaller than 1/4 inch high: Do Not Use Tools To Separate the “Quick... liquefied petroleum gas, and shall be applied to the male threads only. (h) Concealed tubing. Tubing shall...

  5. Application experience of gas-thermal aluminum coatings to protect the pipes for underground construction and repair of heat networks

    Science.gov (United States)

    Kolpakov, A. S.

    2013-11-01

    Questions of sacrificial protection for pipes of underground heat networks with aluminum against the external corrosion are considered. The description of pilot production of pipes with a plasma aluminum coating and the deposition of a sacrificial gas-plasma aluminum coating on weld joints of pipelines and the zone of their thermal influence during assemblage is presented. Examples of repairing the segments of distribution heat networks by the pipes with the tread protection are presented.

  6. PVC pipes in gas distribution: still going strong!

    OpenAIRE

    Hermkens, Rene; Wolters, Mannes; Weller, Jeroen; Visser, Roy; Davidovski, Z.; Belloir, P.; Fumire, J.

    2008-01-01

    In the Netherlands (impact-modified) PVC is the preferred material for low-pressure (30 and 100 mbar) gas distribution systems. More than 50% of the total length (about 122,000 km) of this system is rigid PVC or impact-modified PVC. The installation of rigid PVC (uPVC) pipelines started about 50 years ago. Presently, about 22,500 km of rigid PVC is still in operation. In this paper the good experiences with rigid PVC gas distribution systems in the Netherlands will be illustrated by results o...

  7. Monitoring the evolution and migration of a methane gas plume in an unconfined sandy aquifer using time-lapse GPR and ERT.

    Science.gov (United States)

    Steelman, Colby M; Klazinga, Dylan R; Cahill, Aaron G; Endres, Anthony L; Parker, Beth L

    2017-10-01

    Fugitive methane (CH 4 ) leakage associated with conventional and unconventional petroleum development (e.g., shale gas) may pose significant risks to shallow groundwater. While the potential threat of stray (CH 4 ) gas in aquifers has been acknowledged, few studies have examined the nature of its migration and fate in a shallow groundwater flow system. This study examines the geophysical responses observed from surface during a 72day field-scale simulated CH 4 leak in an unconfined sandy aquifer at Canadian Forces Base Borden, Canada, to better understand the transient behaviour of fugitive CH 4 gas in the subsurface. Time-lapse ground-penetrating radar (GPR) and electrical resistivity tomography (ERT) were used to monitor the distribution and migration of the gas-phase and assess any impacts to groundwater hydrochemistry. Geophysical measurements captured the transient formation of a CH 4 gas plume emanating from the injector, which was accompanied by an increase in total dissolved gas pressure (P TDG ). Subsequent reductions in P TDG were accompanied by reduced bulk resistivity around the injector along with an increase in the GPR reflectivity along horizontal bedding reflectors farther downgradient. Repeat temporal GPR reflection profiling identified three events with major peaks in reflectivity, interpreted to represent episodic lateral CH 4 gas release events into the aquifer. Here, a gradual increase in P TDG near the injector caused a sudden lateral breakthrough of gas in the direction of groundwater flow, causing free-phase CH 4 to migrate much farther than anticipated based on groundwater advection. CH 4 accumulated along subtle permeability boundaries demarcated by grain-scale bedding within the aquifer characteristic of numerous Borden-aquifer multi-phase flow experiments. Diminishing reflectivity over a period of days to weeks suggests buoyancy-driven migration to the vadose zone and/or CH 4 dissolution into groundwater. Lateral and vertical CH 4

  8. PVC pipes in gas distribution: still going strong!

    NARCIS (Netherlands)

    Hermkens, Rene; Wolters, Mannes; Weller, Jeroen; Visser, Roy; Davidovski, Z.; Belloir, P.; Fumire, J.

    2008-01-01

    In the Netherlands (impact-modified) PVC is the preferred material for low-pressure (30 and 100 mbar) gas distribution systems. More than 50% of the total length (about 122,000 km) of this system is rigid PVC or impact-modified PVC. The installation of rigid PVC (uPVC) pipelines started about 50

  9. Transition of Gas-Liquid Stratified Flow in Oil Transport Pipes

    Directory of Open Access Journals (Sweden)

    D. Lakehal

    2011-12-01

    Full Text Available Large-Scale Simulation results of the transition of a gas-liquid stratified flow to slug flow regime in circular 3D oil transport pipes under turbulent flow conditions expressed. Free surface flow in the pipe is treated using the Level Set method. Turbulence is approached via the LES and VLES methodologies extended to interfacial two-phase flows. It is shown that only with the Level Set method the flow transition can be accurately predicted, better than with the two-fluid phase-average model. The transition from stratified to slug flow is found to be subsequent to the merging of the secondary wave modes created by the action of gas shear (short waves with the first wave mode (high amplitude long wave. The model is capable of predicting global flow features like the onset of slugging and slug speed. In the second test case, the model predicts different kinds of slugs, the so-called operating slugs formed upstream that fill entirely the pipe with water slugs of length scales of the order of 2-4 D, and lower size (1-1.5 D disturbance slugs, featuring lower hold-up (0.8-0.9. The model predicts well the frequency of slugs. The simulations revealed important parameter effects on the results, such as two-dimensionality, pipe length, and water holdup.

  10. Experiments on vertical gas-liquid pipe flows using ultrafast X-ray tomography

    Energy Technology Data Exchange (ETDEWEB)

    Banowski, M.; Beyer, M.; Lucas, D.; Hoppe, D.; Barthel, F. [Helmholtz-Zentrum Dresden-Rossendorf (Germany). Inst. fuer Sicherheitsforschung

    2016-12-15

    For the qualification and validation of two-phase CFD-models for medium and large-scale industrial applications dedicated experiments providing data with high temporal and spatial resolution are required. Fluid dynamic parameter like gas volume fraction, bubble size distribution, velocity or turbulent kinetic energy should be measured locally. Considering the fact, that the used measurement techniques should not affect the flow characteristics, radiation based tomographic methods are the favourite candidate for such measurements. Here the recently developed ultrafast X-ray tomography, is applied to measure the local and temporal gas volume fraction distribution in a vertical pipe. To obtain the required frame rate a rotating X-ray source by a massless electron beam and a static detector ring are used. Experiments on a vertical pipe are well suited for development and validation of closure models for two-phase flows. While vertical pipe flows are axially symmetrically, the boundary conditions are well defined. The evolution of the flow along the pipe can be investigated as well. This report documents the experiments done for co-current upwards and downwards air-water and steam-water flows as well as for counter-current air-water flows. The details of the setup, measuring technique and data evaluation are given. The report also includes a discussion on selected results obtained and on uncertainties.

  11. Effectiveness of the Vertical Gas Ventilation Pipes for Promoting Waste Stabilization in Post-Closure Phase

    Directory of Open Access Journals (Sweden)

    Yasumasa Tojo

    2015-06-01

    Full Text Available To make inside of the municipal solid waste (MSW landfill aerobic as much as possible is thought to be preferable for promoting waste stabilization, reducing pollutant's load in leachate, minimizing greenhouse gas emission and shortening post-closure-care period. In Japan, installation of semi-aerobic landfill structure has widely spread in order to promote waste stabilization in MSW landfill from 1980s. In semi-aerobic landfill structure, outlet of main leachate collection pipe is opened to atmosphere. Heat generated by aerobic degradation of waste causes natural convection and natural aeration arises from the outlet of leachate collection pipe to the gas vents. It is so-called stack effect. This air flow is thought to be effective for purifying leachate flowing through drainage layer and leachate collection pipes. And it is also thought to be contributing to expanding aerobic region in waste layer in landfill. Recently, measures attempting the promotion of waste stabilization are taken at several landfills at where stabilization of waste delays, in which many vertical gas vents are newly installed and close structure to semi-aerobic landfill is created. However, in many cases, these gas vents are not connected to leachate collection pipes. Many vertical gas vents are just installed without scientific proof regarding whether they can contribute for waste stabilization. In this study, how such installation of gas vents is effective for waste stabilization and aerobization of waste layer was discussed by numerical analysis. In numerical analysis, heat transfer, gas movement by pressure, gas diffusion, biological degradation of organic matter, and heat generation by biodegradation were taken into account. Simulations were carried out by using the general purpose simulator of finite element method. Three types of landfill structure were assumed. As the results, the following information were obtained. In dig-down type landfill, installation of gas

  12. Modelling of stratified gas-liquid two-phase flow in horizontal circular pipes

    International Nuclear Information System (INIS)

    Sampaio, P.A.B. de; Faccini, J.L.H.; Su, J.

    2006-01-01

    This paper reports numerical and experimental investigation of stratified gas-liquid two-phase flow in horizontal circular pipes. The Reynolds average Navier-Stokes equations (RANS) with κ ω model development stratified gas-liquid two-phase flow are solved by using the finite element methods. A smooth interface surface is assumed without considered the effects of the interfacial waves. The continuity of the shear stress across the interface is enforced with the continuity of the velocity being automatically satisfied by the variational formulation. For it is given position and interface and longitudinal pressure gradient, an inner iteration loop runs to solve nonlinear equations the Newton-Raphson scheme is used to solve the transcendental equations by an outer iteration to determinate the interface position in a 5.2 mm ID circular pipe was measured experimentally by the ultrasonic ultra pulse-echo technique. The numeral were also compared with results in 21 mm ID circular pipe report by Masala (2004). The good agreement between the numerical and experimental results indicates that κ ω model can be applied for the numerical simulation of stratified gas-liquid two phase flow. (author)

  13. Non-destructive monitoring of river embankments using GPR

    Science.gov (United States)

    di Prinzio, Monica; Bittelli, Marco; Castellarin, Attilio; Rossi Pisa, Paola

    2010-05-01

    Non-destructive investigations and controls of civil structures are improving day by day, however the scientific literature reports only a few documented cases of Ground Penetrating Radar (GPR) applications to the detection of voids and discontinuities in hydraulic defense structures such as river embankments and levee systems. GPR can assist decision making in a number of fields by enhancing our knowledge of subsurface features. We applied successfully GPR to the monitoring of river levees for the detectioning of animal burrows in river levees, which may trigger levee failures by piping. The manageability and the non-invasivity of GPR have resulted to be particularly suitable for this application. First because GPR is an extensive investigation method that enables one to rapidly cover a wide area, locating voids that are difficult and costly to locate using other intrusive methods. Second, GPR returns detailed information about the possible presence of voids and discontinuities within river embankments.

  14. Project Scheduling Based on Risk of Gas Transmission Pipe

    Science.gov (United States)

    Silvianita; Nurbaity, A.; Mulyadi, Y.; Suntoyo; Chamelia, D. M.

    2018-03-01

    The planning of a project has a time limit on which must be completed before or right at a predetermined time. Thus, in a project planning, it is necessary to have scheduling management that is useful for completing a project to achieve maximum results by considering the constraints that will exists. Scheduling management is undertaken to deal with uncertainties and negative impacts of time and cost in project completion. This paper explains about scheduling management in gas transmission pipeline project Gresik-Semarang to find out which scheduling plan is most effectively used in accordance with its risk value. Scheduling management in this paper is assissted by Microsoft Project software to find the critical path of existing project scheduling planning data. Critical path is the longest scheduling path with the fastest completion time. The result is found a critical path on project scheduling with completion time is 152 days. Furthermore, the calculation of risk is done by using House of Risk (HOR) method and it is found that the critical path has a share of 40.98 percent of all causes of the occurence of risk events that will be experienced.

  15. A Probabilistic Approach for Predicting Average Slug Frequency in Horizontal Gas/Liquid Pipe Flow

    Directory of Open Access Journals (Sweden)

    Kadri U.

    2013-02-01

    Full Text Available In this paper, we present a model for predicting the average slug frequency in horizontal gas/liquid pipe flow. The model considers the probability of slug formation if slugs are triggered at the antinodes of a sinusoidal perturbation, along the pipe at the frequency of oscillation of the interface. A slug is assumed to form if and only if triggered at a space-time far enough from existing slugs. The probability of forming slugs is found to decrease with distance from the inlet, since the downstream passage of existing slugs prevents the formation of new slugs. Predictions by the model are compared with air/water, freon/water and air/oil measurements found in literature, with a satisfactory agreement. However, a deviation from measurements is observed when considering high viscosity liquid. The model contributes to the prediction of slug flow regime and can act as a guideline toward the design of gas/liquid horizontal pipe flow.

  16. Applied multiphase flow in pipes and flow assurance oil and gas production

    CERN Document Server

    Al-Safran, Eissa M

    2017-01-01

    Applied Multiphase Flow in Pipes and Flow Assurance - Oil and Gas Production delivers the most recent advancements in multiphase flow technology while remaining easy to read and appropriate for undergraduate and graduate petroleum engineering students. Responding to the need for a more up-to-the-minute resource, this highly anticipated new book represents applications on the fundamentals with new material on heat transfer in production systems, flow assurance, transient multiphase flow in pipes and the TUFFP unified model. The complex computation procedure of mechanistic models is simplified through solution flowcharts and several example problems. Containing over 50 solved example problems and 140 homework problems, this new book will equip engineers with the skills necessary to use the latest steady-state simulators available.

  17. Environmentally Assisted Cracking of Drill Pipes in Deep Drilling Oil and Natural Gas Wells

    Science.gov (United States)

    Ziomek-Moroz, M.

    2012-06-01

    Corrosion fatigue (CF), hydrogen induced cracking (HIC) and sulfide stress cracking (SSC), or environmentally assisted cracking (EAC) have been identified as the most challenging causes of catastrophic brittle fracture of drill pipes during drilling operations of deep oil and natural gas wells. Although corrosion rates can be low and tensile stresses during service can be below the material yield stress, a simultaneous action between the stress and corrosive environment can cause a sudden brittle failure of a drill component. Overall, EAC failure consists of two stages: incubation and propagation. Defects, such as pits, second-phase inclusions, etc., serve as preferential sites for the EAC failure during the incubation stage. Deep oil and gas well environments are rich in chlorides and dissolved hydrogen sulfide, which are extremely detrimental to steels used in drilling operations. This article discusses catastrophic brittle fracture mechanisms due to EAC of drill pipe materials, and the corrosion challenges that need to be overcome for drilling ultra-deep oil and natural gas wells.

  18. A Lagrangian Slug Capturing Scheme for Gas-Liquid Flows in Pipes

    Energy Technology Data Exchange (ETDEWEB)

    Renault, Fabien

    2007-06-15

    In this thesis a new Lagrangian numerical scheme for the simulation of gas-liquid flows in pipelines is presented. Based on an approximate two-fluid model, this new scheme, called LASSI (Lagrangian Approximate Scheme for Slug Initiation) is dedicated to the modelling of the transition between stratified and slug flow. It is able to capture directly the slug initiation process and to track the motion of every single slug in the pipe without numerical diffusion. It can thus be qualified as a slug capturing and slug tracking scheme

  19. Development of acoustic flow instruments for solid/gas pipe flows

    International Nuclear Information System (INIS)

    Sheen, S.H.; Raptis, A.C.

    1986-05-01

    Two nonintrusive acoustic flow sensing techniques are reported. One technique, passive in nature, simply measures the bandpassed acoustic noise level produced by particle/particle and particle/wall collisions. The noise levels, given in true RMS voltages or in autocorrelations, show a linear relationship to particle velocity but increase with solid concentration. Therefore, the passive technique requires calibration and a separate measure of solid concentration before it can be used to monitor the particle velocity. The second technique is based on the active cross-correlation principle. It measures particle velocity directly by correlating flow-related signatures at two sensing stations. The velocity data obtained by this technique are compared with measurements by a radioactive-particle time-of-flight (TOF) method. A multiplier of 1.53 is required to bring the acoustic data into agreement with the radioactive TOF result. The difference may originate from the difference in flow fields where particles are detected. The radioactive method senses particles mainly in the turbulent region and essentially measures average particle velocity across the pipe, while the acoustic technique detects particles near the pipe wall, and so measures the particle velocity in the viscous sublayer. Both techniques were tested in flows of limestone and air and 1-mm glass beads and air at the Argonne National Laboratory Solid/Gas Test Facility (SGFTF). The test matrix covered solid velocities of 20 to 30 m/s in a 2-in. pipe and solid-to-gas loading ratios of 6 to 22. 37 refs., 19 figs., 4 tabs

  20. GPR3 and GPR6, novel molecular targets for cannabidiol.

    Science.gov (United States)

    Laun, Alyssa S; Song, Zhao-Hui

    2017-08-12

    GPR3 and GPR6 are members of a family of constitutively active, Gs protein-coupled receptors. Previously, it has been reported that GPR3 is involved in Alzheimer's disease whereas GPR6 plays potential roles in Parkinson's disease. GPR3 and GPR6 are considered orphan receptors because there are no confirmed endogenous agonists for them. However, GPR3 and GPR6 are phylogenetically related to the cannabinoid receptors. In this study, the activities of endocannabinoids and phytocannabinoids were tested on GPR3 and GPR6 using a β-arrestin2 recruitment assay. Among the variety of cannabinoids tested, cannabidiol (CBD), the major non-psychoactive component of marijuana, significantly reduced β-arrestin2 recruitment to both GPR3 and GPR6. In addition, the inhibitory effects of CBD on β-arrestin2 recruitment were concentration-dependent for both GPR3 and GPR6, with a higher potency for GPR6. These data show that CBD acts as an inverse agonist at both GPR3 and GPR6 receptors. These results demonstrate for the first time that both GPR3 and GPR6 are novel molecular targets for CBD. Our discovery that CBD acts as a novel inverse agonist on both GPR3 and GPR6 indicates that some of the potential therapeutic effects of CBD (e.g. treatment of Alzheimer's disease and Parkinson's disease) may be mediated through these important receptors. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Numerical simulations and correlations on the coal -conveying gas flow in pipe for fluidized -bed coal gasification facility

    International Nuclear Information System (INIS)

    Lee, Chan; Lee, Jin Wook; Kwon, Tae Wan; Kim, Gyoo Tae

    2014-01-01

    CFD modeling and simulation are made on the key flow elements, vertical, horizontal pipes and elbow pipes , used in the pneumatic coal -transport system of fluidized -bed gasification test facility. The coal- gas flow inside the flow elements are modeled by combining Reynolds -stress Averaged Navier- Stokes equations Solver (RANS), k- ε turbulence model and Discrete Phase Model (DPM) in the ANSYS Fluent code. Using the developed coal -gas flow analysis model, computations are carried out to investigate the gas flow path, the coal particle behavior and the pressure loss characteristics in flow element at various coal/ gas loading ratio and coal mass flux. The present prediction results show the coal -gas flow behavior of each flow element is changed from dilute -flow to dense -flow pattern at a specific coal/gas loading ratio where pressure loss is abruptly increased. From the numerical results, the present study also provides the limiting coal/gas loading conditions to secure stable coal feeding and the correlations for pressure losses in horizontal, vertical and elbow pipes, which can be suitable for the design guidelines of actual fluidized -bed coal gasification. Key words : Pneumatic Coal -Transport; Coal -Gas Flow, Dense Phase Flow; Dilute Phase Flow; Pressure Loss; Coal/Gas Loading Ratio; Correlation

  2. Prediction of gas volume fraction in fully-developed gas-liquid flow in a vertical pipe

    Energy Technology Data Exchange (ETDEWEB)

    Islam, A.S.M.A.; Adoo, N.A.; Bergstrom, D.J., E-mail: nana.adoo@usask.ca [University of Saskatchewan, Department of Mechanical Engineering, Saskatoon, SK (Canada); Wang, D.F. [Canadian Nuclear Laboratories, Chalk River, ON (Canada)

    2015-07-01

    An Eulerian-Eulerian two-fluid model has been implemented for the prediction of the gas volume fraction profile in turbulent upward gas-liquid flow in a vertical pipe. The two-fluid transport equations are discretized using the finite volume method and a low Reynolds number κ-ε turbulence model is used to predict the turbulence field for the liquid phase. The contribution to the effective turbulence by the gas phase is modeled by a bubble induced turbulent viscosity. For the fully-developed flow being considered, the gas volume fraction profile is calculated using the radial momentum balance for the bubble phase. The model potentially includes the effect of bubble size on the interphase forces and turbulence model. The results obtained are in good agreement with experimental data from the literature. The one-dimensional formulation being developed allows for the efficient assessment and further development of both turbulence and two-fluid models for multiphase flow applications in the nuclear industry. (author)

  3. 77 FR 32626 - Transcontinental Gas Pipe Line Company, LLC; Notice of Intent To Prepare an Environmental Impact...

    Science.gov (United States)

    2012-06-01

    ... at this time. You must wait until the Commission receives a formal application for the project... Gas Pipe Line Company, LLC; Notice of Intent To Prepare an Environmental Impact Statement for the Planned Rockaway Delivery Lateral Project, Request for Comments on Environmental Issues, and Notice of...

  4. Economic feasibility of pipe storage and underground reservoir storage options for power-to-gas load balancing

    International Nuclear Information System (INIS)

    Budny, Christoph; Madlener, Reinhard; Hilgers, Christoph

    2015-01-01

    Highlights: • Study of cost effectiveness of power-to-gas and storage of H 2 and renewable methane. • NPV analysis and Monte Carlo simulation to address fuel and electricity price risks. • Gas sale is compared with power and gas market arbitrage and balancing market gains. • Power-to-gas for linking the balancing markets for power and gas is not profitable. • Pipe storage is the preferred option for temporal arbitrage and balancing energy. - Abstract: This paper investigates the economic feasibility of power-to-gas (P2G) systems and gas storage options for both hydrogen and renewable methane. The study is based on a techno-economic model in which the net present value (NPV) method and Monte Carlo simulation of risks and price forward curves for the electricity and the gas market are used. We study three investment cases: a Base Case where the gas is directly sold in the market, a Storage & Arbitrage Case where temporal arbitrage opportunities between the electricity and the gas market are exploited, and a Storage & Balancing Case where the balancing markets (secondary reserve market for electricity, external balancing market for natural gas) are addressed. The optimal type and size of different centralized and decentralized storage facilities are determined and compared with each other. In a detailed sensitivity and cost analysis, we identify the key factors which could potentially improve the economic viability of the technological concepts assessed. We find that the P2G system used for bridging the balancing markets for power and gas cannot be operated profitably. For both, temporal arbitrage and balancing energy, pipe storage is preferred. Relatively high feed-in tariffs (100 € MW −1 for hydrogen, 130 € MW −1 for methane) are required to render pipe storage for P2G economically viable

  5. Investigation of gas-phase decontamination of internally radioactively contaminated gaseous diffusion process equipment and piping

    International Nuclear Information System (INIS)

    Bundy, R.D.; Munday, E.B.

    1991-01-01

    Construction of the gaseous diffusion plants (GDPs) was begun during World War 2 to produce enriched uranium for defense purposes. These plants, which utilized UF 6 gas, were used primarily for this purpose through 1964. From 1959 through 1968, production shifted primarily to uranium enrichment to supply the nuclear power industry. Additional UF 6 -handling facilities were built in feed and fuel-processing plants associated with the uranium enrichment process. Two of the five process buildings at Oak ridge were shut down in 1964. Uranium enrichment activities at Oak Ridge were discontinued altogether in 1985. In 1987, the Department of Energy (DOE) decided to proceed with a permanent shutdown of the Oak Ridge Gaseous Diffusion Plant (ORGDP). DOE intends to begin decommissioning and decontamination (D ampersand D) of ORGDP early in the next century. The remaining two GDPs are expected to be shut down during the next 10 to 40 years and will also require D ampersand D, as will the other UF 6 -handling facilities. This paper presents an investigation of gas- phase decontamination of internally radioactively contaminated gaseous diffusion process equipment and piping using powerful fluorinating reagents that convert nonvolatile uranium compounds to volatile UF 6 . These reagents include ClF 3 , F 2 , and other compounds. The scope of D ampersand D at the GDPs, previous work of gas-phase decontamination, four concepts for using gas-phase decontamination, plans for further study of gas-phase decontamination, and the current status of this work are discussed. 13 refs., 15 figs

  6. The Numerical Simulation of the Shock Wave of Coal Gas Explosions in Gas Pipe*

    Science.gov (United States)

    Chen, Zhenxing; Hou, Kepeng; Chen, Longwei

    2018-03-01

    For the problem of large deformation and vortex, the method of Euler and Lagrange has both advantage and disadvantage. In this paper we adopt special fuzzy interface method(volume of fluid). Gas satisfies the conditions of conservation equations of mass, momentum, and energy. Based on explosion and three-dimension fluid dynamics theory, using unsteady, compressible, inviscid hydrodynamic equations and state equations, this paper considers pressure gradient’s effects to velocity, mass and energy in Lagrange steps by the finite difference method. To minimize transport errors of material, energy and volume in Finite Difference mesh, it also considers material transport in Euler steps. Programmed with Fortran PowerStation 4.0 and visualized with the software designed independently, we design the numerical simulation of gas explosion with specific pipeline structure, check the key points of the pressure change in the flow field, reproduce the gas explosion in pipeline of shock wave propagation, from the initial development, flame and accelerate the process of shock wave. This offers beneficial reference and experience to coal gas explosion accidents or safety precautions.

  7. Unknown plant de-construction hazard -- Toxic COS and CS2 gas from torch cutting of pipe

    International Nuclear Information System (INIS)

    Martin, H.L.; Nutt, A.W.; Myers, B.L.; Hightower, J.O.

    1994-01-01

    An employee exhibited signs of illness after apparently inhaling fumes generated from a pipe that had been cut with a cutting torch. Identification and quantification of the hazardous air emission for reduction of risk via the Department of Energy Class B Investigation are described in this case study. The old hydrogen sulfide gas flare pipe in the heavy water plant of the Savannah River Site has been abandoned with one end open to atmosphere for almost twenty years. The pipe was being removed and cut into sections for disposal during an asbestos abatement project. It contained ash like corrosion deposits that smolder after torch cutting. Investigation revealed that burning of carbon and sulfur in the oxygen deficient atmosphere in the ash generated carbonyl sulfide (COS) and carbon disulfide (CS 2 ) gas, which vented when the pipe was moved by the injured construction rigger. This is believed to be the first well documented exposure and response of a human to high concentration COS gas. Sulfur dioxide (SO 2 ) gas is also generated during the cutting. SO 2 is almost impossible to inhale and has apparently prevented a similar injury during the cutting. SO 2 is almost impossible to inhale and has apparently prevented a similar injury during the many years of US and Canadian heavy water plant de-construction experience. Immediate water quench of the smoldering ash after each cut has eliminated the hazard of residual COS and CS 2 gas. This previously unrecognized industrial hazard may be encountered by other chemical and petroleum industries during torch cutting of pipes that contain similar deposits of iron oxide, iron sulfate, sulfur and carbon

  8. New gas in old pipes: opening the UK residential gas market to competition

    International Nuclear Information System (INIS)

    Waddams Price, C.; Bennett, M.

    1999-01-01

    The United Kingdom is introducing competition to its residential gas and electricity markets, the first such experiment on a national level. This paper analyses the behaviour of suppliers and consumers in the first market to be opened, based on suppliers' posted prices, two questionnaires to consumers and information from the incumbent. The results confirm predictions about the unwinding of cross-subsidies; a surprisingly small proportion of consumers are switching to other suppliers, and they are not evenly distributed across consumer groups, raising important policy questions about the future of regulation in such markets

  9. Application of GPR to the monitoring of river embankments

    Science.gov (United States)

    Di Prinzio, Monica; Bittelli, Marco; Castellarin, Attilio; Pisa, Paola Rossi

    2010-06-01

    Ground Penetrating Radar (GPR) can assist decision making in a number of fields by enhancing our knowledge of subsurface features. Non-destructive investigations and controls of civil structures are improving day by day, however the scientific literature reports only a few documented cases of GPR applications to the detection of voids and discontinuities in hydraulic defense structures such as river embankments and levee systems. We applied GPR to the monitoring of river levees for detecting animal burrows, which may trigger levee failures by piping. The manageability and the non-invasiveness of GPR have resulted to be particularly suitable for this application. First because GPR is an extensive investigation method that enables one to rapidly cover a wide area, locating voids that are difficult and costly to locate using other intrusive methods. Second, GPR returns detailed information about the possible presence of voids and discontinuities within river embankments. We document a series of successful GPR applications to detect animal burrows in river levees.

  10. Boundary element method applied to a gas-fired pin-fin-enhanced heat pipe

    Energy Technology Data Exchange (ETDEWEB)

    Andraka, C.E.; Knorovsky, G.A.; Drewien, C.A.

    1998-02-01

    The thermal conduction of a portion of an enhanced surface heat exchanger for a gas fired heat pipe solar receiver was modeled using the boundary element and finite element methods (BEM and FEM) to determine the effect of weld fillet size on performance of a stud welded pin fin. A process that could be utilized by others for designing the surface mesh on an object of interest, performing a conversion from the mesh into the input format utilized by the BEM code, obtaining output on the surface of the object, and displaying visual results was developed. It was determined that the weld fillet on the pin fin significantly enhanced the heat performance, improving the operating margin of the heat exchanger. The performance of the BEM program on the pin fin was measured (as computational time) and used as a performance comparison with the FEM model. Given similar surface element densities, the BEM method took longer to get a solution than the FEM method. The FEM method creates a sparse matrix that scales in storage and computation as the number of nodes (N), whereas the BEM method scales as N{sup 2} in storage and N{sup 3} in computation.

  11. Investigation and prediction of slug flow characteristics in highly viscous liquid and gas flows in horizontal pipes

    OpenAIRE

    Zhao, Y.; Lao, Liyun; Yeung, H.

    2015-01-01

    Slug flow characteristics in highly viscous liquid and gas flow are studied experimentally in a horizontal pipe with 0.074 m ID and 17 m length. Results of flow regime map, liquid holdup and pressure gradient are discussed and liquid viscosity effects are investigated. Applicable correlations which are developed to predict liquid holdup in slug body for low viscosity flow are assessed with high viscosity liquids. Furthermore, a mechanistic model is developed for predicting the characteristics...

  12. Measurement of gas-liquid two-phase flow in micro-pipes by a capacitance sensor.

    Science.gov (United States)

    Ji, Haifeng; Li, Huajun; Huang, Zhiyao; Wang, Baoliang; Li, Haiqing

    2014-11-26

    A capacitance measurement system is developed for the measurement of gas-liquid two-phase flow in glass micro-pipes with inner diameters of 3.96, 2.65 and 1.56 mm, respectively. As a typical flow regime in a micro-pipe two-phase flow system, slug flow is chosen for this investigation. A capacitance sensor is designed and a high-resolution and high-speed capacitance measurement circuit is used to measure the small capacitance signals based on the differential sampling method. The performance and feasibility of the capacitance method are investigated and discussed. The capacitance signal is analyzed, which can reflect the voidage variation of two-phase flow. The gas slug velocity is determined through a cross-correlation technique using two identical capacitance sensors. The simulation and experimental results show that the presented capacitance measurement system is successful. Research work also verifies that the capacitance sensor is an effective method for the measurement of gas liquid two-phase flow parameters in micro-pipes.

  13. Measurement of Gas-Liquid Two-Phase Flow in Micro-Pipes by a Capacitance Sensor

    Directory of Open Access Journals (Sweden)

    Haifeng Ji

    2014-11-01

    Full Text Available A capacitance measurement system is developed for the measurement of gas-liquid two-phase flow in glass micro-pipes with inner diameters of 3.96, 2.65 and 1.56 mm, respectively. As a typical flow regime in a micro-pipe two-phase flow system, slug flow is chosen for this investigation. A capacitance sensor is designed and a high-resolution and high-speed capacitance measurement circuit is used to measure the small capacitance signals based on the differential sampling method. The performance and feasibility of the capacitance method are investigated and discussed. The capacitance signal is analyzed, which can reflect the voidage variation of two-phase flow. The gas slug velocity is determined through a cross-correlation technique using two identical capacitance sensors. The simulation and experimental results show that the presented capacitance measurement system is successful. Research work also verifies that the capacitance sensor is an effective method for the measurement of gas liquid two-phase flow parameters in micro-pipes.

  14. Spinning pipe gas lens aberrations along the axis and in the boundary layer

    CSIR Research Space (South Africa)

    Mafusire, C

    2013-11-01

    Full Text Available When the walls of an open-ended horizontal steel pipe are heated before the pipe is rotated along its axis, the exchange of the expelled heated air with the incoming cooler air, sucked in along the axis, results in a medium capable of focusing a...

  15. Development, manufacturing and testing of a gas-loaded variable conductance methanol heat pipe

    Science.gov (United States)

    Vanbuggenum, R. I. J.; Daniels, D. H. W.

    1987-02-01

    The experimental technology required to measure the performance of moderate temperature heat pipes is presented. The heat pipe manufacturing process is described. The hydrodynamic characteristics of the porous structure inside the heat pipe envelope were examined using a specially developed test rig, based upon a steady-state evaporation test. A fully automated test facility was developed and validated by testing constant conductance and variable conductance heat pipes (VCHP). Theoretical performance predictions are illustrated in terms of pressure, depicted in 3D-plots, and compared with the test results of the heat pipe performance tests. The design of the VCHP was directed towards the verification of the VCHP mathematical model. The VCHP design is validated and ready for the final testing and model verification.

  16. Mechanical Properties of High-Nb X80 Steel Weld Pipes for the Second West-to-East Gas Transmission Pipeline Project

    Directory of Open Access Journals (Sweden)

    Gui-ying Qiao

    2017-01-01

    Full Text Available The mechanical properties of steel pipe have great effects on the integrality and operation safety of gas transmission pipeline. In order to reduce the cost of the steel pipe, the high-Nb X80 pipeline steels with the different alloying systems have been used in the Second West-to-East Gas Transmission Pipeline Project. Nevertheless, an investigation into the effects of chemical composition on the mechanical properties of steel pipes is lacking. In this work, the chemical composition and mechanical properties of high-Nb X80 grade steel pipes with a diameter of ϕ1,219 mm and a wall thickness of 22 mm, which are coiled by steels manufactured by three mills, have been analyzed. Furthermore, the effects of chemical composition of the steels on the mechanical properties of the pipe body and weld joint were discussed.

  17. Design and testing of a heat pipe gas combustion system for the STM4-120 Stirling engine

    Science.gov (United States)

    Khalili, K.; Godett, T. M.; Meijer, R. J.; Verhey, R. P.

    Evaporators of a novel geometry, designed to have a more compact size yet the same output as larger, conventional heat pipes, have been fabricated and tested. A technique was developed to calculate capillary pressure required inside the heat pipe. Several quarter- and full-scale evaporators were designed and successfully tested. The burner, film-cooled combustion chamber, and preheater were designed and tested separately. A complete heat pipe gas combustion system (HPGC) was tested, showing an efficiency of 89 percent was measured at 20 kWth. A film-cooled combustion chamber was tested with flame temperatures of 2200 C and wall temperatures below 1000 C using preheated air for film cooling. Also, a full-scale HPGC was tested at an excess of 95 kWth, showing efficiency in the range of 85 to 90 percent under steady-state conditions. Results of transient and startup tests, carried out to evaluate the performance of the heat pipe, all also reported.

  18. Numerical modelling of isothermal gas-liquid two-phase bubbly flow in vertical pipes

    International Nuclear Information System (INIS)

    Yamoah, S.

    2014-07-01

    lubrication and turbulent dispersion force models. Overall, the comparison has shown that the MUSIG model yielded satisfactory agreement with the experimental data. The transition from wall peak to core peak gas volume fraction profiles has been successfully captured and encouraging results clearly exemplified the capability of the model in capturing the dynamical changes of bubble size due to coalescence and breakup processes. The observed agreement with the gas volume fraction profiles indicates a level of confidence in the interfacial force models (especially the lift coefficient model) used, while on the other hand, the agreement seen on the interfacial area concentration indicates that the birth and death processes modelled are reasonably adequate to describe the bubble dynamics. Nevertheless, noticeable discrepancies in simulating bimodal bubble size distributions were found revealing the plausible imperfection of existing coalescence and breakup kernels. Thirdly, the performance of the interfacial area transport equation has been assessed by implementing some typical constitutive models for bubble coalescence and breakup taken from literature. The interfacial area transport equation has been successfully implemented into the CFD code and the constitutive model formulations from Hibiki and Ishii (2000a), Wu et al. (1998) with coefficients from Ishii and Kim (2001) and Wang (2010) have been implemented and validated. The combined effects of lift and wall lubrication force have been investigated. Both models of the lATE source and sink terms were able to reasonably capture the experimental data especially the gas volume fraction profiles. More experimental and theoretical work needs to be done in this field to increase the prediction capability of the simulation tools regarding the distribution of the phases along the pipe radius. (au)

  19. The pipes for gas and oil pipelines mains one-sided high-speed welding

    Directory of Open Access Journals (Sweden)

    Сергій Вікторович Щетинін

    2016-11-01

    Full Text Available Electromagnetic theory of the undercuts formation under the arc magnetic field action according to which as welding speed increases cooling intensifies and arc diameter reduces, induction and magnetic pressure increase, pinch-effect amplifies, has been proved. The arc concentrates, heat input and the pool side edges electrical resistance reduce with the result that current through the side walls and a downward electromagnetic force, under the action of which the liquid metal flows from the pool edges, increase and the undercuts form. In high-speed welding a composite electrode as compared with the wire electrode the heat input into the side edges and their electrical resistance increase; current and induction at the pool side edges and the electromagnetic force decrease that providing the seams qualitative formation and confirming the electromagnetic theory of the undercuts. With welding speed increasing the weld pool molten metal crystallization rate increases in proportion to it, microstructure gets reduced and welding stresses decrease, that providing the welds joints toughness rise. By increasing welding speed due to deflection rearward the arc pressure decreases, the molten metal movement rate into the back part of the pool grows, that resulting in the molten metal hydrodynamic pressure reduction. Due to simultaneous reduction of the arc pressure, of the downward electromagnetic force and of the molten metal hydrodynamic pressure, the crystallization rate increase and the pool molten state time reduction the backing bead formation on the melt backing improves greatly at the high-speed welding. The energy-saving process of one-sided high-speed welding of the pipes for gas and oil pipelines on the melt backing with the use of glass flux by means of a composite electrode, which provides quality and the welded joints toughness increase, has been developed

  20. Ground penetrating radar (GPR) evidence for variations in free phase carbon gas accumulation as a function of peatland landforms: a comparison between near-crest bogs and mid-slope lawns

    Science.gov (United States)

    Parsekian, A.; Slater, L.; Comas, X.; Nolan, J.; Glaser, P.

    2009-05-01

    Northern peatlands serve as atmospheric sources of biogenic free-phase gas (FPG) produced under anaerobic conditions below the water table (mostly methane and carbon dioxide). Recent evidence suggest that FPG accumulates in the subsurface under confining layers and is released during sudden ebullition events, often triggered by sudden drops in atmospheric pressure. Accurate quantification of the impact of FPG releases on the global carbon budget is needed given recent observations of increasing atmospheric methane concentrations. One important step towards understanding the dynamics of FPG in peatlands is to investigate whether certain peatland landforms (i.e. areas with significantly different vegetation patterns) may be more conducive to FPG accumulation and/or release. Additionally, it is important to determine the vertical distribution of FPG within the peat soil and the potential role of peat stratigraphy on gas accumulation and release. In this study, we used common mid-point (CMP) velocity surveys to predict vertical profiles of FPG accumulations by comparing two different peatland landforms: historically forested near-crest bogs and non- forested mid-slope lawns in the Glacial Lake Agassiz Peatland of Minnesota, USA. We show that there is a statistically significant difference in electromagnetic (EM) wave velocities calculated over gas-rich intervals in the peat strata compared to gas-poor intervals. Common-offset radar profiles identified laterally continuous woody confining layers responsible for FPG accumulation. Chaotic GPR facies containing diffraction hyperbolae at the forested near-crest sites are interpreted as deformation of the peat matrix due to FPG accumulation and/or peat fabric disturbance during FPG release events. In contrast, non-forested mid-slope lawn sites, are characterized by planar GPR facies with no evidence of peat fabric disturbance and small relative changes in interpreted EM velocity distribution along the peat column. Using the

  1. Flooding characteristics of gas-liquid two-phase flow in a horizontal U bend pipe

    Energy Technology Data Exchange (ETDEWEB)

    Sakaguchi, T.; Hosokawa, S.; Fujii, Y. [Kobe Univ. (Japan)] [and others

    1995-09-01

    For next-generation nuclear reactors, hybrid safety systems which consist of active and passive safety systems have been planned. Steam generators with horizontal U bend pipelines will be used as one of the passive safety systems. It is required to clarify flow characteristics, especially the onset of flooding, in the horizontal U bend pipelines in order to examine their safety. Flooding in vertical pipes has been studied extensively. However, there is little study on flooding in the horizontal U bend pipelines. It is supposed that the onset of flooding in the horizontal U bend pipelines is different from that in vertical pipes. On the other hand, liquid is generated due to condensation of steam in pipes of the horizontal steam generators at the loss of coolant accident because the steam generators will be used as a condenser of a cooling system of steam from the reactor. It is necessary to simulate this situation by the supply of water at the middle of horizontal pipe. In the present paper, experiments were carried out using a horizontal U bend pipeline with a liquid supply section in the midway of pipeline. The onset of flooding in the horizontal U bend pipeline was measured. Effects of the length of horizontal pipe and the radius of U bend on the onset of flooding were discussed.

  2. Flooding characteristics of gas-liquid two-phase flow in a horizontal U bend pipe

    International Nuclear Information System (INIS)

    Sakaguchi, T.; Hosokawa, S.; Fujii, Y.

    1995-01-01

    For next-generation nuclear reactors, hybrid safety systems which consist of active and passive safety systems have been planned. Steam generators with horizontal U bend pipelines will be used as one of the passive safety systems. It is required to clarify flow characteristics, especially the onset of flooding, in the horizontal U bend pipelines in order to examine their safety. Flooding in vertical pipes has been studied extensively. However, there is little study on flooding in the horizontal U bend pipelines. It is supposed that the onset of flooding in the horizontal U bend pipelines is different from that in vertical pipes. On the other hand, liquid is generated due to condensation of steam in pipes of the horizontal steam generators at the loss of coolant accident because the steam generators will be used as a condenser of a cooling system of steam from the reactor. It is necessary to simulate this situation by the supply of water at the middle of horizontal pipe. In the present paper, experiments were carried out using a horizontal U bend pipeline with a liquid supply section in the midway of pipeline. The onset of flooding in the horizontal U bend pipeline was measured. Effects of the length of horizontal pipe and the radius of U bend on the onset of flooding were discussed

  3. Failures Analysis of E-Glass Fibre reinforced pipes in Oil and Gas Industry: A Review

    Science.gov (United States)

    Bobba, Sujith; Leman, Z.; Zainuddin, E. S.; Sapuan, S. M.

    2017-07-01

    A comprehensive review is conducted on the failures in the field of manufacturing and installation of E-glass fiber reinforced pipes (GFRP). Some of the failures which are mainly encountered after the installation of E-Glass fiber reinforced pipes are the for nation of air bubbles in between the polyester resin layer and the surface film, dispersion of moisture in between the tubing outer and inner layers after installation, heat released in between the layers of E-glass fiber reinforced pipes due to exothermic reaction which in turn results in the formation of cracks on the surface of the pipe. The recent findings and challenges performed in conducting research regarding the deterioration caused in glass fiber reinforced pipes are highlighted and each type of failure that was identified was illustrated with an appropriate high resolution photograph. Performing creep resistance and fatigue analysis are new aspects which are still requited to be analyzed which ave not been stated in the literature which are nominated.

  4. Monitoring the mass of UF6 gas and uranium deposits in aluminium pipes using X-ray fluorescence and X-ray transmission gauges

    International Nuclear Information System (INIS)

    Packer, T.W.; Smith, S.M.

    1984-12-01

    In order to determine the enrichment of UF 6 gas in centrifuge plant pipework it is necessary to measure the mass of the gas (pressure) and the mass per unit area of any uranium deposited on the pipe. This paper shows that it is possible to determine the pressure of the UF 6 gas in pipes 120 mm in diameter using an energy-dispersive X-ray fluorescence spectrometer. Results are also given of transmission measurements made using a low power X-ray generator operated at two different applied voltages. A method of using the two measurements to determine the mass per unit area of deposited uranium is described. (author)

  5. Development of a computer program for the simulation of gas permeation through the walls of flexible pipes

    Energy Technology Data Exchange (ETDEWEB)

    Mello, Paulo Eduardo Batista de [Dept. de Engenharia Mecanica. Centro Universitario da FEI, Sao Bernardo do Campo, SP (Brazil)], e-mail: pmello@fei.edu.br; Barbosa Neto, Teofilo Ferreira; Godinho, Carlos Alberto [Prysmian, Vila Velha, ES (Brazil)], e-mails: teofilo.barbosa@prysmian.com, carlos.godinho@prysmian.com; Yanagihara, Jurandir Itizo [Dept. de Engenharia Mecanica. Escola Politecnica. Universidade de Sao Paulo, SP (Brazil)], e-mail: jiy@usp.br

    2010-07-01

    The design of flexible pipes, used in the petroleum industry, must consider a great number of failure modes. Among them, the problems due to chemical corrosion in the metallic layers that constitute the armors are of the foremost importance. These armors are protected by polymer sheaths, internally and externally, forming one annular space. The gas that is transported by the flexible pipe permeates continuously through the polymer sheaths, increasing the pressure in the annular space. This work presents the transient numerical method and results obtained with a computer code capable of simulating the process of permeation of gases through polymer walls considering the radial and axial directions. The program is capable of predicting the chemical composition in the annulus, at given design conditions of the flexible pipe. Temperature distribution in the radial direction is also calculated in order to consider the variation of mass diffusion coefficients with temperature. The venting process of the annular space, that is used for this kind of equipment, is considered in the simulations. (author)

  6. CFD Modeling of Gas-Liquid Bubbly Flow in Horizontal Pipes: Influence of Bubble Coalescence and Breakup

    Directory of Open Access Journals (Sweden)

    K. Ekambara

    2012-01-01

    Full Text Available Modelling of gas-liquid bubbly flows is achieved by coupling a population balance equation with the three-dimensional, two-fluid, hydrodynamic model. For gas-liquid bubbly flows, an average bubble number density transport equation has been incorporated in the CFD code CFX 5.7 to describe the temporal and spatial evolution of the gas bubbles population. The coalescence and breakage effects of the gas bubbles are modeled. The coalescence by the random collision driven by turbulence and wake entrainment is considered, while for bubble breakage, the impact of turbulent eddies is considered. Local spatial variations of the gas volume fraction, interfacial area concentration, Sauter mean bubble diameter, and liquid velocity are compared against experimental data in a horizontal pipe, covering a range of gas (0.25 to 1.34 m/s and liquid (3.74 to 5.1 m/s superficial velocities and average volume fractions (4% to 21%. The predicted local variations are in good agreement with the experimental measurements reported in the literature. Furthermore, the development of the flow pattern was examined at three different axial locations of L/D = 25, 148, and 253. The first location is close to the entrance region where the flow is still developing, while the second and the third represent nearly fully developed bubbly flow patterns.

  7. Characterization of linear interfacial waves in a turbulent gas-liquid pipe flow

    Science.gov (United States)

    Ayati, A. A.; Farias, P. S. C.; Azevedo, L. F. A.; de Paula, I. B.

    2017-06-01

    The evolution of interfacial waves on a stratified flow was investigated experimentally for air-water flow in a horizontal pipe. Waves were introduced in the liquid level of stratified flow near the pipe entrance using an oscillating plate. The mean height of liquid layer and the fluctuations superimposed on this mean level were captured using high speed cameras. Digital image processing techniques were used to detect instantaneous interfaces along the pipe. The driving signal of the oscillating plate was controlled by a D/A board that was synchronized with acquisitions. This enabled to perform phase-locked acquisitions and to use ensemble average procedures. Thereby, it was possible to measure the temporal and spatial evolution of the disturbances introduced in the flow. In addition, phase-locked measurements of the velocity field in the liquid layer were performed using standard planar Particle Image Velocimetry (PIV). The velocity fields were extracted at a fixed streamwise location, whereas the measurements of the liquid level were performed at several locations along the pipe. The assessment of the setup was important for validation of the methodology proposed in this work, since it aimed at providing results for further comparisons with theoretical models and numerical simulations. Therefore, the work focuses on validation and characterization of interfacial waves within the linear regime. Results show that under controlled conditions, the wave development can be well captured and reproduced. In addition, linear waves were observed for liquid level oscillations lower than about 1.5% of the pipe diameter. It was not possible to accurately define an amplitude threshold for the appearance of nonlinear effects because it strongly depended on the wave frequency. According to the experimental findings, longer waves display characteristics similar to linear waves, while short ones exhibit a more complex evolution, even for low amplitudes.

  8. GPR applied to mapping utilities along the route of the Line 4 (yellow) subway tunnel construction in São Paulo City, Brazil

    Science.gov (United States)

    Porsani, Jorge Luís; Ruy, Yang Boo; Ramos, Fernanda Pereira; Yamanouth, Gisele R. B.

    2012-05-01

    The rapid industrial development and disorganized population growth in huge cities bring about various urban problems due to intense use of physical space on and below the surface. Subsurface problems in metropolitan areas are caused by subway line construction, which often follows the routes of utility networks, such as electric and telephone cables, water and gas pipes, storm sewers, etc. Usually, the main problems are related to damage or destruction of preexisting utilities, often putting human lives at risk. With the purpose of minimizing risks, GPR-profiling with 200 MHz antennae was done at two sites, both located in downtown São Paulo, Brazil. The objectives of this work were to map utilities or existing infrastructure in the subsurface in order to orient the construction of the Line 4 (yellow) subway tunnel in São Paulo. GPR profiles can detect water pipes, utility networks in the subsurface, and concrete foundation columns or pilings in subsoil up to 2 m depth. In addition, the GPR profiles also provided details of the target shapes in the subsurface. GPR interpretations combined with lithological information from boreholes and trenches opened in the study areas were extremely important in mapping of the correct spatial distribution of buried utilities at these two sites in São Paulo. This information improves and updates maps of utility placement, serves as a basis for planning of the geotechnical excavation of the Line 4 (yellow) subway tunnel in São Paulo, helps minimize problems related to destruction of preexisting utilities in the subsoil, and avoids risk of dangerous accidents.

  9. Monitoring underground water leakage pattern by ground penetrating radar (GPR) using 800 MHz antenna frequency

    Science.gov (United States)

    Amran, T. S. T.; Ismail, M. P.; Ahmad, M. R.; Amin, M. S. M.; Ismail, M. A.; Sani, S.; Masenwat, N. A.; Basri, N. S. M.

    2018-01-01

    Water is the most treasure natural resources, however, a huge amount of water are lost during its distribution that leads to water leakage problem. The leaks meant the waste of money and created more economic loss to treat and fix the damaged pipe. Researchers and engineers have put tremendous attempts and effort, to solve the water leakage problem especially in water leakage of buried pipeline. An advanced technology of ground penetrating radar (GPR) has been established as one of the non-destructive testing (NDT) method to detect the underground water pipe leaking. This paper focuses on the ability of GPR in water utility field especially on detection of water leaks in the underground pipeline distribution. A series of laboratory experiments were carried out using 800-MHz antenna, where the performance of GPR on detecting underground pipeline and locating water leakage was investigated and validated. A prototype to recreate water-leaking system was constructed using a 4-inch PVC pipe. Different diameter of holes, i.e. ¼ inch, ½ inch, and ¾ inch, were drilled into the pipe to simulate the water leaking. The PVC pipe was buried at the depth of 60 cm into the test bed that was filled with dry sand. 15 litres of water was injected into the PVC pipe. The water leakage patterns in term of radargram data were gathered. The effectiveness of the GPR in locating the underground water leakage was ascertained, after the results were collected and verified.

  10. GPR Experiments of the Simulated Cavity Detection in Urban Areas

    Science.gov (United States)

    Kim, Changryol; Kang, Woong; Son, Jeongsul; Jeong, Soocheol

    2017-04-01

    Recent years, the deteriorated underground facilities such as sewage or water supply pipes have increased significantly with growing urban development in Korea. The soils surrounding old damaged pipes were washed away beneath the roadbed, causing underground cavities and eventual ground cave-ins in the urban areas. The detection of the roadbed cavities is, therefore, required to prevent property damage and loss of human lives for precautionary measures. In general, GPR is well known as a suitable geophysical technique for shallow underground cavity detection. 3-D GPR technique was applied to conduct the full-scale experiment for roadbed cavity detection. The physical experiment has employed the testing ground with soil characteristics of silty sand soils. The experimental test ground consists of physically simulated cavities with dome-shaped structure, and of hume concrete and cast-iron pipes to simulate underground facilities. The pipes were installed more than one meter below the land surface and simulated cavities nearby were also installed at regular intervals in spatial distribution. The land surface of the site was not paved with asphalt concrete at the current stage of the experiments. The GPR data was obtained to investigate GPR responses due to different antenna orientations (HH and VV antenna orientations) over the testing ground. The results of the experiment show that the reflection patterns from the simulated cavities are hyperbolic returns typical to the point source in 2-D perspective. The different antenna orientations have shown the different areal extents of the hyperbolic reflections patterns from the cavities, and have shown the different characteristics over the pipes on the data. A closer inspection of 3-D GPR volume data has yielded more clear interpretation than 2-D GPR data regarding where the cavities are situated and what kind of shape the cavities show in space. This study is an ongoing project of KIGAM at a second stage of the physical

  11. Development of intelligent pipe locator

    Science.gov (United States)

    Miyamoto, Y.; Wasa, Y.

    1986-08-01

    An inductive pipe locator was developed, so that the position and depth of an underground gas pipe can be accurately located by passing an ac current to the pipe and measuring the generated magnetic field. An ac current (several to 100 kHz) of several tens of mA is transmitted to the underground pipe, and a magnetic sensor above the ground catches the induced magnetic field to estimate the position and depth of the pipe.

  12. Efficient simulation of gas-liquid pipe flows using a generalized population balance equation coupled with the algebraic slip model

    KAUST Repository

    Icardi, Matteo

    2014-09-01

    The inhomogeneous generalized population balance equation, which is discretized with the direct quadrature method of moment (DQMOM), is solved to predict the bubble size distribution (BSD) in a vertical pipe flow. The proposed model is compared with a more classical approach where bubbles are characterized with a constant mean size. The turbulent two-phase flow field, which is modeled using a Reynolds-Averaged Navier-Stokes equation approach, is assumed to be in local equilibrium, thus the relative gas and liquid (slip) velocities can be calculated with the algebraic slip model, thereby accounting for the drag, lift, and lubrication forces. The complex relationship between the bubble size distribution and the resulting forces is described accurately by the DQMOM. Each quadrature node and weight represents a class of bubbles with characteristic size and number density, which change dynamically in time and space to preserve the first moments of the BSD. The predictions obtained are validated against previously published experimental data, thereby demonstrating the advantages of this approach for large-scale systems as well as suggesting future extensions to long piping systems and more complex geometries. © 2014 Elsevier Inc.

  13. 46 CFR 153.294 - Marking of piping systems.

    Science.gov (United States)

    2010-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Piping Systems and Cargo Handling Equipment § 153.294 Marking of piping systems. (a) Each cargo piping system...

  14. 46 CFR 153.281 - Piping to independent tanks.

    Science.gov (United States)

    2010-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Piping Systems and Cargo Handling Equipment § 153.281 Piping to independent tanks. Piping for an independent...

  15. Extensive optimisation analyses of the piping of two large underground gas storage ariel compressors

    NARCIS (Netherlands)

    Eijk, A.; Korst, H.J.C.; Ploumen, G.; Heyer, D.

    2007-01-01

    Two large identical 6-cylinder Ariel JGB/6 compressors of each 7.5 Mw, are used for the underground gas storage (UGS) plant of Essent in Epe, Germany. The compressors can be operated at a wide range of operating conditions, e.g. variable suction and discharge pressures, 2-stage mode during gas

  16. Transients in pipes

    International Nuclear Information System (INIS)

    Marchesin, D.; Paes-Leme, P.J.S.; Sampaio, R.

    1981-01-01

    The motion of a fluid in a pipe is commonly modeled utilizing the one space dimension conservation laws of mass and momentum. The development of shocks and spikes utilizing the uniform sampling method is studied. The effects of temperature variations and friction are compared for gas pipes. (Author) [pt

  17. Monitoring and localization of buried plastic natural gas pipes using passive RF tags

    Science.gov (United States)

    Mondal, Saikat; Kumar, Deepak; Ghazali, Mohd. Ifwat; Chahal, Prem; Udpa, Lalita; Deng, Yiming

    2018-04-01

    A passive harmonic radio frequency (RF) tag on the pipe with added sensing capabilities is proposed in this paper. Radio frequency identification (RFID) based tagging has already emerged as a potential solution for chemical sensing, location detection, animal tagging, etc. Harmonic transponders are already quite popular compared to conventional RFIDs due to their improved signal to noise ratio (SNR). However, the operating frequency, transmitted power and tag efficiency become critical issues for underground RFIDs. In this paper, a comprehensive on-tag sensing, power budget and frequency analyses is performed for buried harmonic tag design. Accurate tracking of infrastructure burial depth is proposed to reduce the probability of failure of underground pipelines. Burial depth is estimated using phase information of received signals at different frequencies calculated using genetic algorithm (GA) based optimization for post processing. Suitable frequency range is determined for a variety of soil with different moisture content for small tag-antenna size. Different types of harmonic tags such as 1) Schottky diode, 2) Non-linear Transmission Line (NLTL) were compared for underground applications. In this study, the power, frequency and tag design have been optimized to achieve small antenna size, minimum signal loss and simple reader circuit for underground detection at up to 5 feet depth in different soil medium and moisture contents.

  18. Gas Gun Model and Comparison to Experimental Performance of Pipe Guns Operating with Light Propellant Gases and Large Cryogenic Pellets

    Energy Technology Data Exchange (ETDEWEB)

    Reed, J. R. [University of Tennessee, Knoxville (UTK); Carmichael, J. R. [Fermi National Accelerator Laboratory (FNAL); Gebhart, T. E. [University of Florida, Gainesville; Combs, Stephen Kirk [ORNL; Baylor, Larry R. [ORNL; Rasmussen, David A. [ORNL; Meitner, Steven J. [ORNL; Lyttle, Mark S. [ORNL

    2017-10-01

    Injection of multiple large (~10 to 30 mm diameter) shattered pellets into ITER plasmas is presently part of the scheme planned to mitigate the deleterious effects of disruptions on the vessel components. To help in the design and optimize performance of the pellet injectors for this application, a model referred to as “the gas gun simulator” has been developed and benchmarked against experimental data. The computer code simulator is a Java program that models the gas-dynamics characteristics of a single-stage gas gun. Following a stepwise approach, the code utilizes a variety of input parameters to incrementally simulate and analyze the dynamics of the gun as the projectile is launched down the barrel. Using input data, the model can calculate gun performance based on physical characteristics, such as propellant-gas and fast-valve properties, barrel geometry, and pellet mass. Although the model is fundamentally generic, the present version is configured to accommodate cryogenic pellets composed of H2, D2, Ne, Ar, and mixtures of them and light propellant gases (H2, D2, and He). The pellets are solidified in situ in pipe guns that consist of stainless steel tubes and fast-acting valves that provide the propellant gas for pellet acceleration (to speeds ~200 to 700 m/s). The pellet speed is the key parameter in determining the response time of a shattered pellet system to a plasma disruption event. The calculated speeds from the code simulations of experiments were typically in excellent agreement with the measured values. With the gas gun simulator validated for many test shots and over a wide range of physical and operating parameters, it is a valuable tool for optimization of the injector design, including the fast valve design (orifice size and volume) for any operating pressure (~40 bar expected for the ITER application) and barrel length for any pellet size (mass, diameter, and length). Key design parameters and proposed values for the pellet injectors for

  19. Stepped Frequency GPR for Utility Line Detection using Polarization Dependent Scattering

    DEFF Research Database (Denmark)

    Jensen, Ole Kiel; Gregersen, Ole

    2000-01-01

    A GPR for detection of buried cables and pipes is developed by Ekko Dome Production in cooperation with Aalborg University. The appearance is a "lawn mower" model including antennas, electronics and on-line data processing. A successful result is obtained by combining dedicated hardware and signal...

  20. Ecoulements intermittents de gaz et de liquide en conduite verticale Intermittent Gas and Liquid Flows in a Vertical Pipe.

    Directory of Open Access Journals (Sweden)

    Line A.

    2006-11-01

    Full Text Available Le modèle présenté ici permet la pré-détermination du gradient de pression, du taux global de gaz, et de grandeurs caractéristiques de l'intermittence, dans un écoulement à poches et bouchons en conduite verticale. L'écriture des lois de conservation en moyenne phasique conditionnelle conduit à la définition d'une cellule moyenne équivalente. La fermeture du modèle est assurée par des lois de contrainte de cisaillement film-paroi, film-poche, bouchon-paroi, par une loi d'arrachage du gaz au culot de la poche, une loi de glissement du gaz dans les bouchons et par une loi de la vitesse moyenne de propagation des fronts de poches. Le calibrage et la qualification du modèle s'appuient sur deux banques de données, dont l'une a été obtenue avec des fluides pétroliers dans des conditions proches des situations industrielles (boucle diphasique de Boussens. The model described here can be used to predetermine the pressure gradient, the overall gas rate and the characteristic intermittence magnitudes in pocket and slug flow in a vertical pipe. The way governing equations in the conditional phase average are written defines an equivalent average cell. The model is closed by film/wall, film/pocket and slug/wall shear-stress laws, by a pulloff law for the gas at the bottom of the pocket, a slippage law for the gas in the slugs, and a mean propagation velocity law for the pocket fronts. The calibration and qualification of the model are based on two data banks, one of which contains data on petroleum fluids under conditions close to industrial situations (two-phase loop at Boussens.

  1. Understanding Passive Layer Formation for Further Corrosion Management in Gas Production Pipes

    Science.gov (United States)

    Santoso, R. K.; Rahmawati, S. D.; Gadesa, A.; Wahyuningrum, D.

    2017-07-01

    Corrosion is a critical issue during the development of a gas field, especially wet gas or retrograde gas field. Corrosion affects the management system of a field and further impacts the amount of investment. Therefore, accurate prediction of corrosion rate is needed to plan an effective preventive action before going further to the development phase. One of the important parameters that should be noticed to create an accurate prediction is the formation of the passive layer. In CO2-H2S environment, there will be three possibilities of passive layer: FeS, FeCO3 or no passive layer. In this study, we create mathematical models to determine the formed passive layer in each segment of the gas production tubing and pipeline. The model is built using Faraday’s Law and Thermodynamic approach to account the passive layer formation at different temperature, pH, corrosion rate and partial pressure of CO2 and H2S. From the simulation, it was found that there were three boundary conditions: no scale-FeS boundary, no scale-FeCO3 boundary and FeS-FeCO3 boundary. The first two boundaries evolved over a time as the concentration of Fe2+ ions was increasing. However, FeS-FeCO3 boundary remained steady as it was not affected by the addition of Fe2+ ions. Using sample case study, few variations were noticed at production pipeline and tubing. It was caused by the gas composition, which contained high CO2 and very low H2S. Boundary conditions only changed slightly over two days period.

  2. Experimental on two sensors combination used in horizontal pipe gas-water two-phase flow

    International Nuclear Information System (INIS)

    Wu, Hao; Dong, Feng

    2014-01-01

    Gas-water two phase flow phenomenon widely exists in production and living and the measurement of it is meaningful. A new type of long-waist cone flow sensor has been designed to measure two-phase mass flow rate. Six rings structure of conductance probe is used to measure volume fraction and axial velocity. The calibration of them have been made. Two sensors have been combined in horizontal pipeline experiment to measure two-phase flow mass flow rate. Several model of gas-water two-phase flow has been discussed. The calculation errors of total mass flow rate measurement is less than 5% based on the revised homogeneous flow model

  3. MORPHOTECTONIC ANALYSIS AT TANIMBAR TRENCH AS A BASE FOR GAS PIPE LAYING BETWEEN MASELA BLOCK AND SELARU ISLAND, MOLUCCAS PROVINCE

    Directory of Open Access Journals (Sweden)

    Ediar Usman

    2017-07-01

    Full Text Available The study area is located at Masela Block and its surrounding, Moluccas Province. Result of the deep sea measurement and global data conversion provide description of three dimensions around the track lines area. This result is overlay with seismic data, that can give morphotectonic implication between Asian and Australian Plates. Track lines of MGI-2010-MSL-1, 2 and 3 show that the profile of the sea floor, form the high morphology which represents the volcanic islands. It forms west – east direction of fold-thrust belt non-volcanic outer Banda arc. The southern part trench of the Australian Continent reflected the platform system and undulation morphology. The sea floor profile ( VE 1:5 show that the slope profile ranges between 0º and 8º. Furthermore, the morphology of the sea floor can be classified as a relatively flat slope. Due to this condition, this area may be used for gas pipe laying along 146 km distance, between the Well of Abadi 1 at the Masela Block and Selaru Island at south Tanimbar Islands.

  4. 75 FR 39680 - Houston Pipe Line Company LP, Worsham-Steed Gas Storage, L.P., Energy Transfer Fuel, LP, Mid...

    Science.gov (United States)

    2010-07-12

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-44-000; Docket No. PR10-46-000; Docket No. PR10-48- 000; Docket No. PR10-49-000; Docket No. PR10-50-000] Houston Pipe Line Company LP, Worsham-Steed Gas Storage, L.P., Energy Transfer Fuel, LP, Mid Continent Market Center, L.L.C...

  5. Proposed systematic methodology for analysis of Pb-210 radioactivity in residues produced in Brazilian natural gas pipes

    International Nuclear Information System (INIS)

    Ferreira, Aloisio Cordilha

    2003-11-01

    Since the 80's, the potential radiological hazards due to the handling of solid wastes contaminated with Rn-222 long-lived progeny - Pb-210 in special - produced in gas pipes and removed by pig operations have been subject of growing concern abroad our country. Nevertheless, little or no attention has been paid to this matter in the Brazilian plants up to now, being these hazards frequently underestimated or even ignored. The main purpose of this work was to propose a systematic methodology for analysis of Pb-210 radioactivity in black powder samples from some Brazilian plants, through the evaluation of direct Pb-210 gamma spectrometry and Bi-210 beta counting technical viabilities. In both cases, one in five samples of black powder analysed showed relevant activity (above 1Bq/kg) of Pb-210, being these results probably related to particular features of each specific plant (production levels, reservoir geochemical profile, etc.), in such a way that a single pattern is not observed. For the proposed methodology, gamma spectrometry proved to be the most reliable technique, showing a 3.5% standard deviation, and, for a 95% confidence level, overall fitness in the range of Pb-210 concentration of activity presented in the standard sample reference sheet, provided by IAEA for intercomparison purposes. In the Brazilian scene, however, the availability of statistically supported evidences is insufficient to allow the potential radiological hazard due to the management of black powder to be discarded. Thus, further research efforts are recommended in order to detect the eventually critical regions or plants where gas exploration, production and processing practices will require a regular program of radiological surveillance, in the near future. (author)

  6. Pipe Penetrating Radar: a New Tool for the Assessment of Critical Infrastructure

    Science.gov (United States)

    Ekes, C.; Neducz, B.

    2012-04-01

    This paper describes the development of Pipe Penetrating Radar (PPR), the underground in-pipe application of GPR, a non-destructive testing method that can detect defects and cavities within and outside mainline diameter (>18 in / 450mm) non-metallic (concrete, PVC, HDPE, etc.) underground pipes. The method uses two or more high frequency GPR antennae carried by a robot into underground pipes. The radar data is transmitted to the surface via fibre optic cable and is recorded together with the output from CCTV (and optionally sonar and laser). Proprietary software analyzes the data and pinpoints defects or cavities within and outside the pipe. Thus the testing can identify existing pipe and pipe bedding symptoms that can be addressed to prevent catastrophic failure due to sinkhole development and can provide useful information about the remaining service life of the pipe. The key innovative aspect is the unique ability to map pipe wall thickness and deterioration including cracks and voids outside the pipe, enabling accurate predictability of needed intervention or the timing of replacement. This reliable non-destructive testing method significantly impacts subsurface infrastructure condition based asset management by supplying previously unattainable measurable conditions. Keywords: pipe penetrating radar (PPR), ground penetrating radar (GPR), pipe inspection, concrete deterioration, municipal engineering

  7. Assessing Biogenic Methane Content in Various Peatland Landforms Using GPR

    Science.gov (United States)

    Parsekian, A.; Comas, X.; Nolan, J.; Glaser, P.; Chanton, J.; Slater, L.

    2008-12-01

    Northern peatlands are known to be a source of biogenic methane, although efforts to accurately quantify their impact on the global carbon budget are ongoing. An important step towards a better understanding of the dynamics of methane releases to the atmosphere is to identify peatland landforms (i.e. raised bog, fen water track, open pools) where gas is accumulating in the subsurface compared to places where there is little subsurface methane. Additionally, it is important to identify areas of the vertical peat profile where high volumes of free-phase methane are present. In this study, we use ground penetrating radar (GPR) to acquire data on where free-phase gas (FPG) methane may be accumulating within the peat strata, and then make comparisons between various peatland landforms. 1-dimensional GPR common mid-point velocity analysis has been coupled with innovative subsurface gas sampling to identify the areas within northern peatlands that have significant gas trapped below confining layers in the subsurface. Gas samples are evaluated for total recovered volume and total methane concentration in order to support the GPR findings. Traditional 2-dimensional radar profiles were used to identify and estimate the depth at which laterally continuous woody confining layers are present, and therefore zones where gas can be expected to be found. By using 1-D, 2-D and direct sampling methods, it is now possible to identify potential areas of gas accumulation with a higher level of confidence.

  8. Development of Innovating Materials for Distributing Mixtures of Hydrogen and Natural Gas. Study of the Barrier Properties and Durability of Polymer Pipes

    Directory of Open Access Journals (Sweden)

    Klopffer Marie-Hélène

    2015-02-01

    Full Text Available With the growing place taken by hydrogen, a question still remains about its delivery and transport from the production site to the end user by employing the existing extensive natural gas pipelines. Indeed, the key challenge is the significant H2 permeation through polymer infrastructures (PolyEthylene (PE pipes, components such as connecting parts. This high flow rate of H2 through PE has to be taken into account for safety and economic requirements. A 3-year project was launched, the aim of which was to develop and assess material solutions to cope with present problems for hydrogen gas distribution and to sustain higher pressure compared to classical high density polyethylene pipe. This project investigated pure hydrogen gas and mixtures with natural gas (20% of CH4 and 80% of H2 in pipelines with the aim to select engineering polymers which are more innovative than polyethylene and show outstanding properties, in terms of permeation, basic mechanical tests but also more specific characterizations such as long term ageing and behaviour. The adequate benches, equipments and scientific approach for materials testing had been developed and validated. In this context, the paper will focus on the evaluation of the barrier properties of 3 polymers (PE, PA11 and PAHM. Experiments were performed for pure H2 and CH4 and also in the presence of mixtures of hydrogen and natural gas in order to study the possible mixing effects of gases. It will report some round-robin tests that have been carried out. Secondly, by comparing data obtained on film, polymer membrane and on pipe section, the influence of the polymer processing will be studied. Innovative multilayers systems will be proposed and compared on the basis of the results obtained on monolayer systems. Finally, the evolution of the transport properties of the studied polymers with an ageing under representative service conditions will be discussed.

  9. Literature review and experimental investigation of heat pipes

    Science.gov (United States)

    Barsch, W. O.; Schoenhals, R. J.; Viskanta, R.; Winter, E. R. F.

    1971-01-01

    Tests on heat pipes determine operational limits, external boundary conditions, noncondensable gas effects, startup behavior, and geometric configurations. Experiment consists of design, construction, and testing of an apparatus for measuring wick properties, conventional heat pipes and coplanar heat pipes.

  10. Ground penetrating radar (GPR) analysis : Phase I.

    Science.gov (United States)

    2009-11-01

    "The objective of this work is to evaluate the feasibility of expanding the MDT's Ground Penetrating : Radar (GPR) program to a broader range of pavement evaluation activities. Currently, MDT uses GPR in : conjunction with its Falling Weight Deflecto...

  11. Polymer pipes for distributing mixtures of hydrogen and natural gas. Evolution of their transport and mechanical properties after an ageing under an hydrogen environment

    Energy Technology Data Exchange (ETDEWEB)

    Klopffer, Marie-Helene [IFP (France); Berne, Philippe [CEA (France); Castagnet, Sylvie [ENSMA (France); Weber, Mathilde [Air Liquide (Canada); Hochstetter, Gilles [Arkema (France); Espuche, Eliane [INSA Lyon (France)

    2010-07-01

    With the development of hydrogen as an energy vector, its delivery and transport from the production site to the end user remains an issue. Indeed, the key challenge to overcome is the high hydrogen permeation through existing polymer infrastructures used for natural gas distribution (Polyethylene pipes, components as connecting parts). This high flow rate of hydrogen through polymer has to be taken into account for safety and economical requirements. This 3-year project investigates pure hydrogen gas and mixtures (20% CH4 - 80% H2) in pipelines made of engineering polymers to develop and assess material solutions to cope with today problems for H2 distribution. Materials such as polyethylene (PE100) and polyamide 11 (PA11) have been studied. PE100 is considered as a reference material as it is used today in natural gas distribution pipes. PA11 should allow a higher operating pressure combined with better gas-barrier performances. Test benches and protocols for testing materials in terms of mechanical and barrier properties were first developed. The materials have then been studied in terms of barrier, mechanical properties and on a microstructural point of view. The properties of the raw material and samples after ageing in presence of hydrogen in various conditions were compared to assess the long term behaviour in service. These results as well as the comparison between PA11 and PE are presented. (orig.)

  12. 46 CFR 119.430 - Engine exhaust pipe installation.

    Science.gov (United States)

    2010-10-01

    ... an exhaust pipe. (b) Exhaust gas must not leak from the piping or any connections. The piping must be... stresses resulting from the expansion of the exhaust piping. (g) A dry exhaust pipe must: (1) If it passes... discharge terminating in a transom must be located as far outboard as practicable so that exhaust gases...

  13. GPR scan assessment

    Directory of Open Access Journals (Sweden)

    Abbas M. Abbas

    2015-06-01

    Full Text Available Mekaad Radwan monument is situated in the neighborhood of Bab Zuweila in the historical Cairo, Egypt. It was constructed at the middle XVII century (1635 AD. The building has a rectangle shape plan (13 × 6 m with the longitudinal sides approximately WNW-ESE. It comprises three storages namely; the ground floor; the opened floor (RADWAN Bench and the living floor with a total elevation of 15 m above the street level. The building suffers from severe deterioration phenomena with patterns of damage which have occurred over time. These deterioration and damages could be attributed to foundation problems, subsoil water and also to the earthquake that affected the entire Greater Cairo area in October 1992. Ground Penetrating Radar (GPR scan was accomplished against the walls of the opened floor (RADWAN Bench to evaluate the hazard impact on the walls textures and integrity. The results showed an anomalous feature through the southern wall of RADWAN Bench. A mathematical model has been simulated to confirm the obtained anomaly and the model response exhibited a good matching with the outlined anomaly.

  14. An acoustic technique for tracing plastic pipe

    Energy Technology Data Exchange (ETDEWEB)

    Huebler, J.E.; Campbell, B.K. (Inst. of Gas Technology, Chicago, IL (United States)); Ching, G.K. (Southern California Gas Co., Los Angeles, CA (United States). Research Dept.)

    1993-08-01

    Many operation and maintenance activities performed by a gas distribution company require precise knowledge of the location of the gas main and/or service. These activities range from pipe location for the repair of a leak to the marking of pipe location as part of a one call system. Records provide one method of knowing the location of piping; however, these records are not always sufficiently accurate for field work. Thus, techniques for pipe location have always been an important need of the industry, and electromagnetic pipe locators have filled this need for years. Electromagnetic pipe locators, however, cannot find plastic pipe unless a tracer wire is buried next to or above the pipe. With the increased use of plastic pipe, a new technique for finding buried pipe is required. A successful acoustic plastic pipe locator could eliminate the use of tracer wire in new polyethylene pipe installations, thereby reducing pipe installation costs. Under sponsorship of the Southern California Gas Company, the Institute of Gas Technology (IGT) successfully demonstrated the proof-of-concept of an active acoustic plastic pipe location technique and is developing the technique into a practical field instrument.

  15. Numerical Study of Planar GPR Antenna Measurements

    DEFF Research Database (Denmark)

    Meincke, Peter; Hansen, Thorkild

    2004-01-01

    The formulation of planar near-field measurements of GPR antennas determines the plane-wave spectra of the GPR antenna in terms of measurements obtained with a buried probe as the GPR antenna moves over a scan plane on the ground. A numerical study investigates how the formulation is affected by (1...

  16. GPR119 as a fat sensor

    DEFF Research Database (Denmark)

    Hansen, Harald S; Rosenkilde, Mette M; Holst, Jens Juul

    2012-01-01

    acting through, for example, GPR40, but is also probably mediated in large part through the luminal formation of 2-monoacylglycerol acting on the 'fat sensor' GPR119. In the pancreas GPR119 may also be stimulated by 2-monoacylglycerol generated from local turnover of pancreatic triacylglycerol. Knowledge...

  17. 46 CFR 153.280 - Piping system design.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Piping system design. 153.280 Section 153.280 Shipping... BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Piping Systems and Cargo Handling Equipment § 153.280 Piping system design. (a) Each cargo piping system must meet...

  18. Studies on the characteristics of the separated heat pipe system with non-condensible gas for the use of the passive decay heat removal in reactor systems

    International Nuclear Information System (INIS)

    Hayashi, Takao; Ishi, Takayuki; Hayakawa, Hitoshi; Ohashi, Kazutaka

    1997-01-01

    Experiments on the separated heat pipe system of variable conductance type, which enclose non-condensible gas, have been carried out with intention of applying such system to passive decay heat removal of the modular reactors such as HTR plant. Basic experiments have been carried out on the experimental apparatus consisting of evaporator, vapor transfer tube, condenser tube and return tube which returns the condensed liquid back to the evaporator. Water and methanol were examined as the working fluids and nitrogen gas was enclosed as the non-condensible gas. The behaviors of the system were examined for the parametric changes of the heat input under the various pressures of nitrogen gas initially enclosed, including the case without enclosing N 2 gas for the comparison. The results of the experiments shows very clear features of self control characteristics. The self control mechanism was made clear, that is, in such system in which the condensing area in the condenser expands automatically in accordance with the increase of the heat input to keep the system temperature nearly constant. The working temperature of the system are clearly dependent on the pressure of the non-condensable gas initially enclosed, with higher system working temperature with higher initial gas pressure enclosed. The analyses were done on water and methanol as the working fluids, which show very good agreement with the experimental results. A lot of attractive applications are expected including the self switching feature with minimum heat loss during normal operation with maintaining the sufficient heat removal at accidents. (author)

  19. Void fraction development in gas-liquid flow after a U-bend in a vertically upwards serpentine-configuration large-diameter pipe

    Science.gov (United States)

    Almabrok, Almabrok A.; Aliyu, Aliyu M.; Baba, Yahaya D.; Lao, Liyun; Yeung, Hoi

    2018-01-01

    We investigate the effect of a return U-bend on flow behaviour in the vertical upward section of a large-diameter pipe. A wire mesh sensor was employed to study the void fraction distributions at axial distances of 5, 28 and 47 pipe diameters after the upstream bottom bend. The study found that, the bottom bend has considerable impacts on up-flow behaviour. In all conditions, centrifugal action causes appreciable misdistribution in the adjacent straight section. Plots from WMS measurements show that flow asymmetry significantly reduces along the axis at L/D = 47. Regime maps generated from three axial locations showed that, in addition to bubbly, intermittent and annular flows, oscillatory flow occurred particularly when gas and liquid flow rates were relatively low. At this position, mean void fractions were in agreement with those from other large-pipe studies, and comparisons were made with existing void fraction correlations. Among the correlations surveyed, drift flux-type correlations were found to give the best predictive results.

  20. A novel radial anode layer ion source for inner wall pipe coating and materials modification--hydrogenated diamond-like carbon coatings from butane gas.

    Science.gov (United States)

    Murmu, Peter P; Markwitz, Andreas; Suschke, Konrad; Futter, John

    2014-08-01

    We report a new ion source development for inner wall pipe coating and materials modification. The ion source deposits coatings simultaneously in a 360° radial geometry and can be used to coat inner walls of pipelines by simply moving the ion source in the pipe. Rotating parts are not required, making the source ideal for rough environments and minimizing maintenance and replacements of parts. First results are reported for diamond-like carbon (DLC) coatings on Si and stainless steel substrates deposited using a novel 360° ion source design. The ion source operates with permanent magnets and uses a single power supply for the anode voltage and ion acceleration up to 10 kV. Butane (C4H10) gas is used to coat the inner wall of pipes with smooth and homogeneous DLC coatings with thicknesses up to 5 μm in a short time using a deposition rate of 70 ± 10 nm min(-1). Rutherford backscattering spectrometry results showed that DLC coatings contain hydrogen up to 30 ± 3% indicating deposition of hydrogenated DLC (a-C:H) coatings. Coatings with good adhesion are achieved when using a multiple energy implantation regime. Raman spectroscopy results suggest slightly larger disordered DLC layers when using low ion energy, indicating higher sp(3) bonds in DLC coatings. The results show that commercially interesting coatings can be achieved in short time.

  1. Mathematical model of nonisothermal turbulent flow of gas suspension in a pipe on the basis of the mixed Eulerian-Lagrangian representation

    International Nuclear Information System (INIS)

    Starchenko, A.V.; Bubenchikov, A.M.; Burlutskij, E.S.

    2002-01-01

    The mathematical model of the gas suspension nonisothermal turbulent flow in a pipe is formulated within the frames of the mixed Eulerian-Lagrangian representation. The model testing showed good agreement of the calculational results with the experiments as well as with the continuous model data. Application of two essentially differing approaches (the continuous and mixed ones) to modeling the density flow practically to similar results by the fields of averaged velocities and temperatures as well as by the coefficient of accommodation of the tangential velocity component and essentially of the particles collision with the wall surface [ru

  2. Co-current air-water flow in downward sloping pipes : Transport of capacity reducing gas pockets in wastewater mains

    NARCIS (Netherlands)

    Pothof, I.W.M.

    2011-01-01

    Air-water flow is an undesired condition in many systems for the transportation of water or wastewater. Air in storm water tunnels may get trapped and negatively affect the system. Air pockets in hydropower tunnels or sewers may cause blow-back events and inadmissible pressure spikes. Water pipes

  3. Measurements of gravity and gravity-capillary waves in horizontal gas-liquid pipe flow using PIV in both phases

    NARCIS (Netherlands)

    Birvalski, M.; Tummers, M.J.; Henkes, R.A.W.M.

    2016-01-01

    An experimental study was performed in stratified wavy flow of air and water through a horizontal pipe. The velocity fields in both phases were measured simultaneously using PIV and the interfacial shape was resolved using a profile capturing technique. The objective of the study was to

  4. In-Situ Measurements of Low Enrichment Uranium Holdup Process Gas Piping at K-25 - Paper for Waste Management Symposia 2010 East Tennessee Technology Park Oak Ridge, Tennessee

    International Nuclear Information System (INIS)

    Rasmussen, B.

    2010-01-01

    This document is the final version of a paper submitted to the Waste Management Symposia, Phoenix, 2010, abstract BJC/OR-3280. The primary document from which this paper was condensed is In-Situ Measurement of Low Enrichment Uranium Holdup in Process Gas Piping at K-25 Using NaI/HMS4 Gamma Detection Systems, BJC/OR-3355. This work explores the sufficiency and limitations of the Holdup Measurement System 4 (HJVIS4) software algorithms applied to measurements of low enriched uranium holdup in gaseous diffusion process gas piping. HMS4 has been used extensively during the decommissioning and demolition project of the K-25 building for U-235 holdup quantification. The HMS4 software is an integral part of one of the primary nondestructive assay (NDA) systems which was successfully tested and qualified for holdup deposit quantification in the process gas piping of the K-25 building. The initial qualification focused on the measurement of highly enriched UO 2 F 2 deposits. The purpose of this work was to determine if that qualification could be extended to include the quantification of holdup in UO 2 F 2 deposits of lower enrichment. Sample field data are presented to provide evidence in support of the theoretical foundation. The HMS4 algorithms were investigated in detail and found to sufficiently compensate for UO 2 F 2 source self-attenuation effects, over the range of expected enrichment (4-40%), in the North and East Wings of the K-25 building. The limitations of the HMS4 algorithms were explored for a described set of conditions with respect to area source measurements of low enriched UO 2 F 2 deposits when used in conjunction with a 1 inch by 1/2 inch sodium iodide (NaI) scintillation detector. The theoretical limitations of HMS4, based on the expected conditions in the process gas system of the K-25 building, are related back to the required data quality objectives (DQO) for the NBA measurement system established for the K-25 demolition project. The combined

  5. In-Situ Measurements of Low Enrichment Uranium Holdup Process Gas Piping at K-25 - Paper for Waste Management Symposia 2010 East Tennessee Technology Park Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    Rasmussen B.

    2010-01-01

    This document is the final version of a paper submitted to the Waste Management Symposia, Phoenix, 2010, abstract BJC/OR-3280. The primary document from which this paper was condensed is In-Situ Measurement of Low Enrichment Uranium Holdup in Process Gas Piping at K-25 Using NaI/HMS4 Gamma Detection Systems, BJC/OR-3355. This work explores the sufficiency and limitations of the Holdup Measurement System 4 (HJVIS4) software algorithms applied to measurements of low enriched uranium holdup in gaseous diffusion process gas piping. HMS4 has been used extensively during the decommissioning and demolition project of the K-25 building for U-235 holdup quantification. The HMS4 software is an integral part of one of the primary nondestructive assay (NDA) systems which was successfully tested and qualified for holdup deposit quantification in the process gas piping of the K-25 building. The initial qualification focused on the measurement of highly enriched UO{sub 2}F{sub 2} deposits. The purpose of this work was to determine if that qualification could be extended to include the quantification of holdup in UO{sub 2}F{sub 2} deposits of lower enrichment. Sample field data are presented to provide evidence in support of the theoretical foundation. The HMS4 algorithms were investigated in detail and found to sufficiently compensate for UO{sub 2}F{sub 2} source self-attenuation effects, over the range of expected enrichment (4-40%), in the North and East Wings of the K-25 building. The limitations of the HMS4 algorithms were explored for a described set of conditions with respect to area source measurements of low enriched UO{sub 2}F{sub 2} deposits when used in conjunction with a 1 inch by 1/2 inch sodium iodide (NaI) scintillation detector. The theoretical limitations of HMS4, based on the expected conditions in the process gas system of the K-25 building, are related back to the required data quality objectives (DQO) for the NBA measurement system established for the K-25

  6. 46 CFR 153.283 - Valving for cargo piping.

    Science.gov (United States)

    2010-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Piping Systems and Cargo Handling Equipment § 153.283 Valving for cargo piping. (a) Except as described in this...

  7. Product back-tracing in piping systems made out of polyethylene for the gas supply; Produkte-Rueckverfolgbarkeit in Rohrnetz-Systemen aus Polyethylen fuer die Gasversorgung

    Energy Technology Data Exchange (ETDEWEB)

    Keller, F. [Fischer (G.) AG, Schaffhausen (Switzerland)

    2001-02-01

    Everyone involved in providing piping systems for gas and water supply in particular, is nowadays challenged by a large and various range of demands. Slogans like quality management, product liability, service provider's obligation of due care, cost reduction, profitability of the enterprises involved etc. confront each other at the most diverse and varying angles of juxtaposition. Where it is necessary to reconcile various interests with differing demands, electronic documentation of all data which serves the purpose of back-tracing should be implemented. Now, the new traceability system creates the necessary preconditions for a regularised and reliable system for standardisation, for piping and fitting manufacturers and for the producers of welding equipment. (orig.) [German] Alle Beteiligten, die bei der Erstellung von Rohrnetzen speziell fuer die Gas- und Wasserversorgung involviert sind, werden heute mit den unterschiedlichsten Anforderungen konfrontiert. Schlagworte wie Qualitaetssicherung, Produkthaftung, Sorgfaltspflicht der Dienstleister, Kostenreduktion, Profitabilitaet der beteiligten Unternehmen usw. stehen sich unter den verschiedenen Blickwinkeln gegenueber. Muessen die unterschiedlichen Interessen mit den verschiedenen Anforderungen in Uebereinstimmung gebracht werden, dann sollte eine elektronische Dokumentation aller der Rueckverfolgbarkeit dienenden relevanten Daten realisierbar sein. Auf der Basis des neuen Rueckverfolgbarkeits-Systems sind heute alle Voraussetzungen fuer ein einheitliches und sicheres System seitens der Normung, der Rohr- und Fittinghersteller sowie den Produzenten von Schweissgeraeten verfuegbar. Nun gilt es fuer die Betreiber und Netzverantwortlichen, dieses kostenguenstige Hilfsmittel adaequat und klar strukturiert in Ihren Unternehmungen einzusetzen, um den Anforderungen bezueglich einer durchgehenden Qualitaetssicherung gerecht zu werden. (orig.)

  8. CAPACITIVE TOMOGRAPHY FOR THE LOCATION OF PLASTIC PIPE

    Energy Technology Data Exchange (ETDEWEB)

    Brian J. Huber

    2003-04-30

    Throughout the utility industry, there is high interest in subsurface imaging of plastic, ceramic, and metallic objects because of the cost, reliability, and safety benefits available in avoiding impacts with the existing infrastructure and in reducing inappropriate excavations. Industry interest in locating plastic pipe has resulted in funding available for the development of technologies that enable this imaging. Gas Technology Institute (GTI) proposes to develop a compact and inexpensive capacitive tomography imaging sensor that takes the form of a flat plate or flexible mat that can be placed on the ground to image objects embedded in the soil. A compact, low-cost sensor that can image objects through soil could be applied to multiple operations and will produce a number of cost savings for the gas industry. In a stand-alone mode, it could be used to survey an area prior to excavation. The technology would improve the accuracy and reliability of any operation that involves excavation by locating or avoiding buried objects. An accurate subsurface image of an area will enable less costly keyhole excavations and other cost-saving techniques. Ground penetrating radar (GPR) has been applied to this area with limited success. Radar requires a high-frequency carrier to be injected into the soil: the higher the frequency, the greater the image resolution. Unfortunately, high-frequency radio waves are more readily absorbed by soil. Also, high-frequency operation raises the cost of the associated electronics. By contrast, the capacitive tomography sensor uses low frequencies with a multiple-element antenna to obtain good resolution. Low-frequency operation lowers the cost of the associated electronics while improving depth of penetration. The objective of this project is to combine several existing techniques in the area of capacitive sensing to quickly produce a demonstrable prototype. The sensor itself will take the form of a flat array of electrodes that can be

  9. CAPACITIVE TOMOGRAPHY FOR THE LOCATION OF PLASTIC PIPE

    Energy Technology Data Exchange (ETDEWEB)

    Brian J. Huber

    2003-01-31

    Throughout the utility industry, there is high interest in subsurface imaging of plastic, ceramic, and metallic objects because of the cost, reliability, and safety benefits available in avoiding impacts with the existing infrastructure and in reducing inappropriate excavations. Industry interest in locating plastic pipe has resulted in funding available for the development of technologies that enable this imaging. Gas Technology Institute (GTI) proposes to develop a compact and inexpensive capacitive tomography imaging sensor that takes the form of a flat plate or flexible mat that can be placed on the ground to image objects embedded in the soil. A compact, low-cost sensor that can image objects through soil could be applied to multiple operations and will produce a number of cost savings for the gas industry. In a stand-alone mode, it could be used to survey an area prior to excavation. The technology would improve the accuracy and reliability of any operation that involves excavation by locating or avoiding buried objects. An accurate subsurface image of an area will enable less costly keyhole excavations and other cost-saving techniques. Ground penetrating radar (GPR) has been applied to this area with limited success. Radar requires a high-frequency carrier to be injected into the soil: the higher the frequency, the greater the image resolution. Unfortunately, high-frequency radio waves are more readily absorbed by soil. Also, high-frequency operation raises the cost of the associated electronics. By contrast, the capacitive tomography sensor uses low frequencies with a multiple-element antenna to obtain good resolution. Low-frequency operation lowers the cost of the associated electronics while improving depth of penetration. The objective of this project is to combine several existing techniques in the area of capacitive sensing to quickly produce a demonstrable prototype. The sensor itself will take the form of a flat array of electrodes that can be

  10. CAPACITIVE TOMOGRAPHY FOR THE LOCATION OF PLASTIC PIPE

    Energy Technology Data Exchange (ETDEWEB)

    Brian J. Huber

    2002-10-30

    Throughout the utility industry, there is high interest in subsurface imaging of plastic, ceramic, and metallic objects because of the cost, reliability, and safety benefits available in avoiding impacts with the existing infrastructure and in reducing inappropriate excavations. Industry interest in locating plastic pipe has resulted in funding available for the development of technologies that enable this imaging. Gas Technology Institute (GTI) proposes to develop a compact and inexpensive capacitive tomography imaging sensor that takes the form of a flat plate or flexible mat that can be placed on the ground to image objects embedded in the soil. A compact, low-cost sensor that can image objects through soil could be applied to multiple operations and will produce a number of cost savings for the gas industry. In a stand-alone mode, it could be used to survey an area prior to excavation. The technology would improve the accuracy and reliability of any operation that involves excavation by locating or avoiding buried objects. An accurate subsurface image of an area will enable less costly keyhole excavations and other cost-saving techniques. Ground penetrating radar (GPR) has been applied to this area with limited success. Radar requires a high-frequency carrier to be injected into the soil: the higher the frequency, the greater the image resolution. Unfortunately, high-frequency radio waves are more readily absorbed by soil. Also, high-frequency operation raises the cost of the associated electronics. By contrast, the capacitive tomography sensor uses low frequencies with a multiple-element antenna to obtain good resolution. Low-frequency operation lowers the cost of the associated electronics while improving depth of penetration. The objective of this project is to combine several existing techniques in the area of capacitive sensing to quickly produce a demonstrable prototype. The sensor itself will take the form of a flat array of electrodes that can be

  11. GPR41 and GPR43¬ in obesity and inflammation – protective or causative?

    OpenAIRE

    Zhiwei eAng; Jeak Ling eDing

    2016-01-01

    GPR41 and GPR43 are a pair of mammalian G-protein coupled receptors (GPCRs) expressed in human adipocytes, colon epithelial cells and peripheral blood mononuclear cells. These receptors are activated by short-chain fatty acids (SCFAs) such as acetate, propionate and butyrate– which are produced during dietary fiber fermentation by resident gut bacteria. This unique ligand specificity suggests that GPR41 and GPR43 may mediate the interaction between the human host and the gut microbiome. Indee...

  12. Promethus Hot Leg Piping Concept

    International Nuclear Information System (INIS)

    AM Girbik; PA Dilorenzo

    2006-01-01

    The Naval Reactors Prime Contractor Team (NRPCT) recommended the development of a gas cooled reactor directly coupled to a Brayton energy conversion system as the Space Nuclear Power Plant (SNPP) for NASA's Project Prometheus. The section of piping between the reactor outlet and turbine inlet, designated as the hot leg piping, required unique design features to allow the use of a nickel superalloy rather than a refractory metal as the pressure boundary. The NRPCT evaluated a variety of hot leg piping concepts for performance relative to SNPP system parameters, manufacturability, material considerations, and comparison to past high temperature gas reactor (HTGR) practice. Manufacturability challenges and the impact of pressure drop and turbine entrance temperature reduction on cycle efficiency were discriminators between the piping concepts. This paper summarizes the NRPCT hot leg piping evaluation, presents the concept recommended, and summarizes developmental issues for the recommended concept

  13. EBI2, GPR18 and GPR17--three structurally related, but biologically distinct 7TM receptors

    DEFF Research Database (Denmark)

    Nørregaard, Kristine; Benned-Jensen, Tau; Rosenkilde, Mette Marie

    2011-01-01

    have been deorphanized, many remain orphan, and these orphan receptors constitute a large pool of potential drug targets. This review focuses on one of these orphan targets, the Epstein-Barr Virus-induced receptor 2, EBI2 (or GPR183), together with two structurally related receptors, GPR17 and GPR18...

  14. GPR utilization in artificial freezing engineering

    International Nuclear Information System (INIS)

    Song, Lei; Yang, Weihao; Huang, Jiahui; Li, Haipeng; Zhang, Xiaojun

    2013-01-01

    To utilize ground penetrating radar (GPR) in artificial freezing engineering (AFE), the electromagnetic parameters (EMP) of frozen soil were measured using a vector network analyser, which showed that the dielectric permittivity and electric conductivity change abruptly at the boundary between the frozen and the non-frozen soil. Then similarity criteria of GPR model experiments were deduced, and GPR laboratory model experiments and field explorations of AFE were carried out. It was found that for AFE, the GPR travel time and profile characters of anomalies in model experiments were similar to those in field explorations, while the amplitude of GPR signals in laboratory model experiments were much stronger than those in field explorations. Numerical simulations were also implemented to analyse the relationship between model experiments and field explorations, which further told us why we could easily find the targets by GPR in the laboratory but not in field explorations. The outputs showed that GPR could be used to detect the thickness of the frozen wall and to find unfrozen soil defects, even though the amplitude of the reflective signals were much weaker than those of laboratory experiments. The research findings have an important theoretical value for AFE and permafrost region engineering, and the deduced GPR similarity criteria could be widely used in other GPR model experiments. (paper)

  15. Practical aspects of acoustic plastic pipe location

    Energy Technology Data Exchange (ETDEWEB)

    Huebler, J.E.; Campbell, B.K. [Institute of Gas Technology, Chicago, IL (United States); Ching, G.K. [Southern California Gas Co. (United States)

    1993-12-31

    Many gas distribution company operation and maintenance activities require precise knowledge of the location of buried plastic piping. Plastic pipe cannot be located if the tracer wire is gone or was never installed. Under sponsorship of the Southern California Gas Company, IGT successfully demonstrated an acoustic plastic pipe location technique and is developing the technique into a practical field instrument an acoustic signal is injected directly into the gas at a service. The acoustic signal travels in the gas in the pipes, not in the pipe wall. As the acoustic wave travels along the pipe, some of the sound radiates from the pipe through the soil to the surface of the ground. An array of sensors on the surface of the ground perpendicular to the pipe detects the acoustic signal, thereby locating the Pipe. Two different acoustic measurements are used. The first measurement locates the pipe to within {plus_minus} 3-ft. Then the second technique determines the location of the pipe to within {plus_minus} 6-in.

  16. PE 100 pipe systems

    CERN Document Server

    Brömstrup, Heiner

    2012-01-01

    English translation of the 3rd edition ""Rohrsysteme aus PE 100"". Because of the considerably increased performance, pipe and pipe systems made from 100 enlarge the range of applications in the sectors of gas and water supply, sewage disposal, industrial pipeline construction and in the reconstruction and redevelopment of defective pipelines (relining). This book applies in particular to engineers, technicians and foremen working in the fields of supply, disposal and industry. Subject matters of the book are all practice-relevant questions regarding the construction, operation and maintenance

  17. Estimating water content in an active landfill with the aid of GPR.

    Science.gov (United States)

    Yochim, April; Zytner, Richard G; McBean, Edward A; Endres, Anthony L

    2013-10-01

    Landfill gas (LFG) receives a great deal of attention due to both negative and positive environmental impacts, global warming and a green energy source, respectively. However, predicting the quantity of LFG generated at a given landfill, whether active or closed is difficult due to the heterogeneities present in waste, and the lack of accurate in situ waste parameters like water content. Accordingly, ground penetrating radar (GPR) was evaluated as a tool for estimating in situ water content. Due to the large degree of subsurface heterogeneity and the electrically conductive clay cap covering landfills, both of which affect the transmission of the electromagnetic pulses, there is much scepticism concerning the use of GPR to quantify in situ water content within a municipal landfill. Two landfills were studied. The first landfill was used to develop the measurement protocols, while the second landfill provided a means of confirming these protocols. GPR measurements were initially completed using the surface GPR approach, but the lack of success led to the use of borehole (BH) GPR. Both zero offset profiling (ZOP) and multiple offset gathers (MOG) modes were tried, with the results indicating that BH GPR using the ZOP mode is the most simple and efficient method to measure in situ water content. The best results were obtained at a separation distance of 2m, where higher the water content, smaller the effective separation distance. However, an increase in water content did appear to increase the accuracy of the GPR measurements. For the effective separation distance of 2m at both landfills, the difference between GPR and lab measured water contents were reasonable at 33.9% for the drier landfill and 18.1% for the wetter landfill. Infiltration experiments also showed the potential to measure small increases in water content. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin

    OpenAIRE

    Meyer, Rebecca C.; Giddens, Michelle M.; Schaefer, Stacy A.; Hall, Randy A.

    2013-01-01

    GPR37 (also known as Pael-R) and GPR37L1 are orphan G protein-coupled receptors that are almost exclusively expressed in the nervous system. We screened these receptors for potential activation by various orphan neuropeptides, and these screens yielded a single positive hit: prosaptide, which promoted the endocytosis of GPR37 and GPR37L1, bound to both receptors and activated signaling in a GPR37- and GPR37L1-dependent manner. Prosaptide stimulation of cells transfected with GPR37 or GPR37L1 ...

  19. Estimating water content in an active landfill with the aid of GPR

    International Nuclear Information System (INIS)

    Yochim, April; Zytner, Richard G.; McBean, Edward A.; Endres, Anthony L.

    2013-01-01

    Highlights: • Limited information in the literature on the use of GPR to measure in situ water content in a landfill. • Developed GPR method allows measurement of in situ water content in a landfill. • Developed GPR method is appealing to waste management professionals operating landfills. - Abstract: Landfill gas (LFG) receives a great deal of attention due to both negative and positive environmental impacts, global warming and a green energy source, respectively. However, predicting the quantity of LFG generated at a given landfill, whether active or closed is difficult due to the heterogeneities present in waste, and the lack of accurate in situ waste parameters like water content. Accordingly, ground penetrating radar (GPR) was evaluated as a tool for estimating in situ water content. Due to the large degree of subsurface heterogeneity and the electrically conductive clay cap covering landfills, both of which affect the transmission of the electromagnetic pulses, there is much scepticism concerning the use of GPR to quantify in situ water content within a municipal landfill. Two landfills were studied. The first landfill was used to develop the measurement protocols, while the second landfill provided a means of confirming these protocols. GPR measurements were initially completed using the surface GPR approach, but the lack of success led to the use of borehole (BH) GPR. Both zero offset profiling (ZOP) and multiple offset gathers (MOG) modes were tried, with the results indicating that BH GPR using the ZOP mode is the most simple and efficient method to measure in situ water content. The best results were obtained at a separation distance of 2 m, where higher the water content, smaller the effective separation distance. However, an increase in water content did appear to increase the accuracy of the GPR measurements. For the effective separation distance of 2 m at both landfills, the difference between GPR and lab measured water contents were reasonable

  20. The impact analysis of the connecting pipe length and diameter on the operation of a piston hybrid power machine of positive displacement with gas suction capacity

    Science.gov (United States)

    Shcherba, V. E.; Grigoriev, A. V.; Averyanov, G. S.; Surikov, V. I.; Vedruchenko, V. P.; Galdin, N. S.; Trukhanova, D. A.

    2017-08-01

    The article analyzes the impact of the connecting liquid pipe length and diameter on consumables and power characteristics of the piston hybrid power machine with gas suction capacity. The following operating characteristics of the machine were constructed and analyzed: the average height of the liquid column in the jacket space; instantaneous velocity and height of the liquid column in the jacket space; the relative height of the liquid column in the jacket space; volumetric efficiency; indicator isothermal efficiency; flowrate in the pump section; relative pressure losses during suction; relative flowrate. The dependence of the instantaneous pressure in the work space and the suction space of the compressor section on the rotation angle of the crankshaft is determined for different values of the length and diameter of the connecting pipeline.

  1. A study on the concentration of CO by the length and the variation of the bent tube of the exhaust pipe for a household gas boiler

    International Nuclear Information System (INIS)

    Leem, Sa Hwan; Huh, Yong Jeong; Lee, Jong Rark

    2008-01-01

    Energy and environment become increasingly serious after the industrial revolution. The demand for gas as an ecofriendly energy source is also increasing. With the demand, the installation and the use of gas boilers have also increased, so the damage to human life by the waste gas (CO and CO 2 ) continues increasing every year. Hence, the aim of this study was to investigate the concentration of CO (Carbon Monoxide) by the length and the variation of the bent tube of the exhaust pipe by installing a boiler with the same method as a household boiler and to discover the harm to humans. For the effect of the length, the allowable concentration of CO is 50ppm, and the 3m of the once bent tube starts exceeding the allowable concentration of CO after 5 minutes, and the 4m and 5m starts exceeding after 3 minutes. In addition, the 1m of three times bent tube starts exceeding the allowable concentration of CO after 3 minutes

  2. Heat pipes

    CERN Document Server

    Dunn, Peter D

    1994-01-01

    It is approximately 10 years since the Third Edition of Heat Pipes was published and the text is now established as the standard work on the subject. This new edition has been extensively updated, with revisions to most chapters. The introduction of new working fluids and extended life test data have been taken into account in chapter 3. A number of new types of heat pipes have become popular, and others have proved less effective. This is reflected in the contents of chapter 5. Heat pipes are employed in a wide range of applications, including electronics cooling, diecasting and injection mo

  3. Prediction of soil effects on GPR signatures

    NARCIS (Netherlands)

    Rhebergen, J.B.; Lensen, H.A.; Wijk, C.V. van; Hendrickx, J.M.H.; Dam, R. van; Borchers, B.

    2004-01-01

    In previous work we have shown that GPR signatures are affected by soil texture and soil water content. In this contribution we will use a three dimensional electromagnetic model and a hydrological soil model to explore in more detail the relationships between GPR signatures, soil physical

  4. 46 CFR 108.449 - Piping tests.

    Science.gov (United States)

    2010-10-01

    ... piping installation. (b) When tested with CO2 or other inert gas under a pressure of 70 kilograms per square centimeter (1000 pounds per square inch), with no additional gas introduced into the system, the leakage in the piping from the cylinders to the stop valves in the manifold must not allow a pressure drop...

  5. 46 CFR 95.15-15 - Piping.

    Science.gov (United States)

    2010-10-01

    ...) Installation test requirements are: (1) Upon completion of the piping installation, and before the cylinders... other inert gas shall be used for this test. (2) The piping from the cylinders to the stop valves in the manifold shall be subjected to a pressure of 1,000 pounds per square inch. With no additional gas being...

  6. 46 CFR 193.15-15 - Piping.

    Science.gov (United States)

    2010-10-01

    ...) Installation test requirements are: (1) Upon completion of the piping installation, and before the cylinders... other inert gas shall be used for this test. (2) The piping from the cylinders to the stop valves in the manifold shall be subjected to a pressure of 1,000 pounds per square inch. With no additional gas being...

  7. Pipe grabber

    Energy Technology Data Exchange (ETDEWEB)

    Sharafutdinov, I.G.; Mubashirov, S.G.; Prokopov, O.I.

    1981-05-15

    A pipe grabber is suggested which contains a housing, clamping elements and centering mechanism with drive installed on the lower end of the housing. In order to improve the reliable operation of the pipe grabber, the centering mechanism is made in the form of a reinforced ringed flexible shaft, while the drive is made in the form of elastic rotating discs. In this case the direction of rotation of the discs and the flexible shaft is the opposite.

  8. 46 CFR 153.292 - Separation of piping systems.

    Science.gov (United States)

    2010-10-01

    ... CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS Design and Equipment Piping Systems and Cargo Handling Equipment § 153.292 Separation of piping systems. Cargo piping systems must be arranged so that operations necessary to provide separate systems can be accomplished in a cargo handling...

  9. Diffusion in flexible pipes

    Energy Technology Data Exchange (ETDEWEB)

    Brogaard Kristensen, S.

    2000-06-01

    This report describes the work done on modelling and simulation of the complex diffusion of gas through the wall of a flexible pipe. The diffusion and thus the pressure in annulus depends strongly on the diffusion and solubility parameters of the gas-polymer system and on the degree of blocking of the outer surface of the inner liner due to pressure reinforcements. The report evaluates the basis modelling required to describe the complex geometries and flow patterns. Qualitatively results of temperature and concentration profiles are shown in the report. For the program to serve any modelling purpose in 'real life' the results need to be validated and possibly the model needs corrections. Hopefully, a full-scale test of a flexible pipe will provide the required temperatures and pressures in annulus to validate the models. (EHS)

  10. COST Action TU1208 - Working Group 2 - GPR surveying of pavements, bridges, tunnels and buildings; underground utility and void sensing

    Science.gov (United States)

    Pajewski, Lara; Benedetto, Andrea; Derobert, Xavier; Fontul, Simona; Govedarica, Miro; Gregoire, Colette; Loizos, Andreas; Perez-Gracia, Vega; Plati, Christina; Ristic, Aleksandar; Tosti, Fabio; Van Geem, Carl

    2017-04-01

    parkings, road tunnels, underground concrete tunnels, bridges, railways, buildings. GPR was also employed to detect cables and pipes, as well as to inspect road construction materials, joints, concrete and wood. A selection of the most interesting results will be presented during the 2017 EGU GA. 7. WG2 contributed to the TU1208 Education Pack, an open-access educational package conceived to teach GPR in University courses. 8. In cooperation with the other Working Groups, WG2 organized Tutorials on Ground Penetrating Radar (Brussels, Belgium, July 2014, and London, United Kingdom, March 2015), as well as Training Schools on "Civil engineering applications of Ground Penetrating Radar" (Pisa, Italy, September 2014), "Applications of Ground Penetrating Radar in urban areas: the sensitive case of historical cities" (Cracow, Poland, May 2015), "Ground Penetrating Radar for road pavement assessment and detection of buried utilities" (London, United Kingdom, October 2015), "Applications of GPR to civil engineering and archaeology" (Valletta, Malta, January 2016), "Non-destructive testing techniques for civil engineering" (Barcelona, Spain, March 2016), and finally "Ground Penetrating Radar for the assessment of transport infrastructure" (Osijek, Croatia, March 2017). 9. In cooperation with the other Working Groups, WG2 organized a series of national events devoted to fostering the interaction with stakeholders, new potential GPR end-users, and interested citizens. During such events, participants could discover what is GPR and how this technique can be effectively used in civil engineering works as well as in different fields ("TU1208 GPR Road Show"). Acknowledgement: The Authors are deeply grateful to COST (European Cooperation in Science and Technology, www.cost.eu), for funding and supporting the COST Action TU1208 "Civil engineering applications of Ground Penetrating Radar" (www.GPRadar.eu).

  11. Migration of dispersive GPR data

    Science.gov (United States)

    Powers, M.H.; Oden, C.P.; ,

    2004-01-01

    Electrical conductivity and dielectric and magnetic relaxation phenomena cause electromagnetic propagation to be dispersive in earth materials. Both velocity and attenuation may vary with frequency, depending on the frequency content of the propagating energy and the nature of the relaxation phenomena. A minor amount of velocity dispersion is associated with high attenuation. For this reason, measuring effects of velocity dispersion in ground penetrating radar (GPR) data is difficult. With a dispersive forward model, GPR responses to propagation through materials with known frequency-dependent properties have been created. These responses are used as test data for migration algorithms that have been modified to handle specific aspects of dispersive media. When either Stolt or Gazdag migration methods are modified to correct for just velocity dispersion, the results are little changed from standard migration. For nondispersive propagating wavefield data, like deep seismic, ensuring correct phase summation in a migration algorithm is more important than correctly handling amplitude. However, the results of migrating model responses to dispersive media with modified algorithms indicate that, in this case, correcting for frequency-dependent amplitude loss has a much greater effect on the result than correcting for proper phase summation. A modified migration is only effective when it includes attenuation recovery, performing deconvolution and migration simultaneously.

  12. Miniature Ground Penetrating Radar, CRUX GPR

    Science.gov (United States)

    Kim, Soon Sam; Carnes, Steven R.; Haldemann, Albert F.; Ulmer, Christopher T.; Ng, Eddie; Arcone, Steven A.

    2006-01-01

    Under NASA instrument development programs (PIDDP 2000-2002, MIPD 2003-2005, ESR and T, 2005) we have been developing miniature ground penetrating radars (GPR) for use in mapping subsurface stratigraphy from planetary rovers for Mars and lunar applications. The Mars GPR is for deeper penetration (up to 50 m depth) into the Martian subsurface at moderate resolution (0.5 m) for a geological characterization. As a part of the CRUX (Construction and Resource Utilization Explorer) instrument suite, the CRUX GPR is optimized for a lunar prospecting application. It will have shallower penetration (5 m depth) with higher resolution (10 cm) for construction operations including ISRU (in-situ resource utilization).

  13. Rutgers/NJDOT Pavement Resource Program (NJDOT Statewide GPR Project Network GPR Data Collection and Analysis Update of HPMA GPR Database)

    Science.gov (United States)

    2008-05-01

    Center for Advanced Transportation Infrastructure (CAIT) of Rutgers University is mandated to conduct Ground Penetrating Radar (GPR) surveys to update the NJDOT's pavement management system with GPR measured pavement layer thicknesses. Based on the r...

  14. Disease-associated mutations prevent GPR56-collagen III interaction.

    Directory of Open Access Journals (Sweden)

    Rong Luo

    Full Text Available GPR56 is a member of the adhesion G protein-coupled receptor (GPCR family. Mutations in GPR56 cause a devastating human brain malformation called bilateral frontoparietal polymicrogyria (BFPP. Using the N-terminal fragment of GPR56 (GPR56(N as a probe, we have recently demonstrated that collagen III is the ligand of GPR56 in the developing brain. In this report, we discover a new functional domain in GPR56(N, the ligand binding domain. This domain contains four disease-associated mutations and two N-glycosylation sites. Our study reveals that although glycosylation is not required for ligand binding, each of the four disease-associated mutations completely abolish the ligand binding ability of GPR56. Our data indicates that these four single missense mutations cause BFPP mostly by abolishing the ability of GPR56 to bind to its ligand, collagen III, in addition to affecting GPR56 protein surface expression as previously shown.

  15. Beam screens for the LHC beam pipes

    CERN Multimedia

    Patrice Loïez

    1997-01-01

    Cross-section of LHC prototype beam pipes showing the beam screens. Slits in the screens allow residual gas molecules to be pumped out and become frozen to the walls of the ultra-cold beam pipe. Beam screens like these have been designed to line the beam pipes, absorbing radiation before it can hit the magnets and warm them up, an effect that would greatly reduce the magnetic field and cause serious damage.

  16. Progress in quantitative GPR development at CNDE

    International Nuclear Information System (INIS)

    Eisenmann, David; Margetan, F. J.; Chiou, C.-P.; Roberts, Ron; Wendt, Scott

    2014-01-01

    Ground penetrating radar (GPR) uses electromagnetic (EM) radiation pulses to locate and map embedded objects. Commercial GPR instruments are generally geared toward producing images showing the location and extent of buried objects, and often do not make full use of available absolute amplitude information. At the Center for Nondestructive Evaluation (CNDE) at Iowa State University efforts are underway to develop a more quantitative approach to GPR inspections in which absolute amplitudes and spectra of measured signals play a key role. Guided by analogous work in ultrasonic inspection, there are three main thrusts to the effort. These focus, respectively, on the development of tools for: (1) analyzing raw GPR data; (2) measuring the EM properties of soils and other embedding media; and (3) simulating GPR inspections. This paper reviews progress in each category. The ultimate goal of the work is to develop model-based simulation tools that can be used assess the usefulness of GPR for a given inspection scenario, to optimize inspection choices, and to determine inspection reliability

  17. Ecoulements diphasiques gaz-liquide à poches et à bouchons en conduites Two-Phase Gas-Liquid Slug Flow in Pipes

    Directory of Open Access Journals (Sweden)

    Ferschneider G.

    2006-11-01

    Full Text Available Les écoulements diphasiques gaz-liquide ont été étudiés afin de contribuer à développer des modèles de calculs prédictifs des pertes de charge dans les conduites de production des bruts pétroliers. Les expériences nécessaires ont été réalisées sur la boucle diphasique de Boussens dans les conditions suivantes représentatives des conditions industrielles : diamètre 6 , longueur 120 m, disposition de la conduite horizontale ou faiblement ascendante, couple de fluide gaz naturel-huile légère. Le gradient de pression, le contenu global, et la distribution locale des phases ont été mesurés. Le traitement des équations de conservation phasique intégrées sur la section par différents types de moyennes a permis de développer un modèle cellulaire qui inclue un nombre limité d'équations constitutives nécessaires à sa fermeture. Ce modèle prédétermine convenablement le gradient de pression, le contenu gaz global et la longueur des poches et des bouchons. Two-phase gas-liquid flows were analyzed so as to develop models for prediction of pressure drops in crude-oil production lines. The experiments were performed on the two-phase loop at Boussens under the following representative industrial conditions: 6 diameter, 120 m length, horizontal or slightly rising pipe, couple of fluids natural gas and light oil. The pressure gradient, average content and local phase distribution were measured. Conservation phase equations integrated along the cross-section were processed by different time-averaged operators so as to develop a cellular model including a limited number of constitutive equations required for its closure. This model suitably predetermines the pressure gradient, the average gas content and the length of gas and liquid slug.

  18. Simulation of close range remote sensing of subsurface features using GPR for urban utility information system development

    Science.gov (United States)

    Hebsur, A. V.; Muniappan, N.; Rao, E. P.; Venkatachalam, G.

    2013-10-01

    In rapidly urbanizing old cities underground utility maps or urban utility information systems seldom exist. Close range remote sensing using Ground penetrating radar (GPR) for detection of the buried utilities is increasingly becoming common. GPR can help in developing or supplementing and updating an urban utility information system. The GPR data (radargram) needs to be interpreted by applying knowledge of buried utility responses under the influence of (a) antenna center frequency (b) host medium relative permittivity, conductivity and (c) object shape, size and material. In view of impracticality of generating utility response information directly in the field, Finite difference time domain (FDTD) simulation of radar wave propagation is carried out. The present work describes the database generation of GPR responses through simulation using an exclusive software GprMaxV2.0. A buried utility pipe produces a hyperbolic pattern in the radargram. In general, utilities may be made of metal, concrete or PVC; may lie within a shallow depth of about 0.5m-1.0m and their diameters may range upto to 1.0m; the relative permittivity of a dry soil could vary from about 4 to 15. Considering these aspects, problem of a pipe buried in soil is formulated, radargrams are simulated and variations of amplitudes and hyperbolic patterns are studied. To minimize the time-intensive simulations, Response surface method (RSM) is used to model amplitudes and hyperbolic patterns as functions of their influencing parameters. A database of simulated responses along with RSM modeling is seen to be a useful component of or complement to an urban utility information system.

  19. Measurement of the enrichment of uranium-hexafluoride gas in product pipes in the centrifuge enrichment plant at Almelo

    International Nuclear Information System (INIS)

    Packer, T.W.; Lees, E.W.; Aaldijk, J.K.; Harry, R.J.S.

    1987-09-01

    One of the objectives of safeguarding centrifuge enrichment plants is to apply non-destructive measurements inside the cascade area to confirm that the enrichment level is in the low enriched uranium range. Research in the UK and USA has developed a NDA instrument which can confirm the presence of low enriched uranium on a rapid go/no go basis in cascade header pipework of their centrifuge enrichment plants. The instrument is based on a gamma spectroscopic measurement coupled with an X-ray fluorescence analysis. This report gives the results of measurements carried out at Almelo by the UKAEA Harwell, ECN Petten and KFA Juelich to determine if these techniques could be employed at Almelo and Gronau. The energy dispersive X-ray fluorescence analysis has been applied to determine the total mass of uranium in the gas phase, and the deposit correction technique and the two geometry technique have been applied at Almelo to correct the measured gamma intensities for those emitted by the deposit. After an executive summary the report discusses the principles of the two correction methods. A short description of the equipment precedes the presentation of the results of the measurements and the discussion. After the conclusions the report contains two appendices which contain the derivation of the formulae for the deposit correction technique and a discussion of the systematic errors of this technique. 8 figs.; 11 refs.; 6 tables

  20. On the whistling of corrugated pipes with narrow cavities

    NARCIS (Netherlands)

    Golliard, J.; Belfroid, S.P.C.; González Diez, N.; Bendiksen, E.; Frimodt, C.

    2013-01-01

    Pipes with a corrugated inner surface, as used inflexible pipes for gas production and transport, can be subject to Flow-Induced Pulsations when the flow velocities are higher than a certain onset velocity. The onset velocity for classical corrugated pipes can be predicted on basis of the geometry

  1. Design and Optimization of UWB for Air Coupled GPR Applications

    Science.gov (United States)

    2014-10-01

    ANTENNA FOR AIR COUPLED GPR APPLICATIONS This thesis presents a novel antenna structure that satisfies the challenging requirements of an air coupled...high speed ground penetrating radar ( GPR ). The desired GPR system is to achieve high spatial resolution and accurate inspection results while scanning... GPR , ground penetrating radar REPORT DOCUMENTATION PAGE 11. SPONSOR/MONITOR’S REPORT NUMBER(S) 10. SPONSOR/MONITOR’S ACRONYM(S) ARO 8

  2. The application of GPR in survey of Yongshan coalmine bridge

    International Nuclear Information System (INIS)

    Liao Yuhua; Deng Juzhi

    2007-01-01

    Ground penetrating radar (GPR) is an effective shoallow exploration method which uses the reflection of high frequency electromagnetism pulse wave to detect the object and geologic phenomena underground. With the development of electron and computer technique, the application domain of this method is keeping enlarge. Based on the working principle of GPR, this paper discussed the good effect of GPR to pier prospecting in Yongshan coal mines. Some matters that should be attentive are posed while using GPR. (authors)

  3. Regulation of energy homeostasis via GPR120

    Directory of Open Access Journals (Sweden)

    Atsuhiko eIchimura

    2014-07-01

    Full Text Available Free fatty acids (FFAs are fundamental units of key nutrients. FFAs exert various biological functions, depending on the chain length and degree of desaturation. Recent studies have shown that several FFAs act as ligands of G-protein-coupled receptors (GPCRs, activate intracellular signaling and exert physiological functions via these GPCRs. GPR120 (also known as free fatty acid receptor 4, FFAR4 is activated by unsaturated medium- to long-chain FFAs and has a critical role in various physiological homeostasis mechanisms such as incretin hormone secretion, food preference, anti-inflammation and adipogenesis. Recent studies showed that a lipid sensor GPR120 has a key role in sensing dietary fat in white adipose tissue and regulates the whole body energy homeostasis in both humans and rodents. Genetic study in human identified the loss-of-functional mutation of GPR120 associated with obesity and insulin resistance. In addition, dysfunction of GPR120 has been linked as a novel risk factor for diet-induced obesity. This review aims to provide evidence from the recent development in physiological function of GPR120 and discusses its functional roles in regulation of energy homeostasis and its potential as drug targets.

  4. Plastic Pipe Failure, Risk, and Threat Analysis

    Science.gov (United States)

    2009-04-29

    The three primary failure modes that may be exhibited by polyethylene (PE) gas pipe materials were described in detail. The modes are: ductile rupture, slow crack growth (SCG), and rapid crack propagation (RCP). Short term mechanical tests were evalu...

  5. Laser-GMA Hybrid Pipe Welding System

    National Research Council Canada - National Science Library

    Reutzel, Edward W; Kern, Ludwig; Sullivan, Michael J; Tressler, Jay F; Avalos, Juan

    2007-01-01

    The combination of laser welding with conventional gas metal arc welding technology offers substantial increases in production rate of joining pipe through single-pass joining compared to multi-pass...

  6. Analysis of pipe stress using CAESAR II code

    International Nuclear Information System (INIS)

    Sitandung, Y.B.; Bandriyana, B.

    2002-01-01

    Analysis of this piping stress with the purpose of knowing stress distribution piping system in order to determine pipe supports configuration. As an example of analysis, Gas Exchanger to Warm Separator Line was chosen with, input data was firstly prepared in a document, i.e. piping analysis specification that its content named as pipe characteristics, material properties, operation conditions, guide equipment's and so on. Analysis result such as stress, load, displacement and the use support type were verified based on requirements in the code, standard, and regularities were suitable with piping system condition analyzed. As the proof that piping system is in safety condition, it can be indicated from analysis results (actual loads) which still under allowable load. From the analysis steps that have been done CAESAR II code fulfill requirements to be used as a tool of piping stress analysis as well as nuclear and non nuclear installation piping system

  7. Stepped Frequency GPR for Utility Line Detection using Polarization Dependent Scattering

    DEFF Research Database (Denmark)

    Jensen, Ole Kiel; Gregersen, Ole

    2000-01-01

    A GPR for detection of buried cables and pipes is developed by Ekko Dome Production in cooperation with Aalborg University. The appearance is a "lawn mower" model including antennas, electronics and on-line data processing. A successful result is obtained by combining dedicated hardware and signal...... antenna array configurations are rested and optimized for low coupling between transmitter and receiver and for a short impulse response. A large number of tests have been made for different targets, e.g. metal cables and plastic pipes filled with air or water. Tests have been made under realistic ground...... conditions, including sand, wet clay, pavements and grass covered soil. The results show reliable detection even when the conditions are difficult....

  8. Heat pipes

    CERN Document Server

    Dunn, Peter D

    1982-01-01

    A comprehensive, up-to-date coverage of the theory, design and manufacture of heat pipes and their applications. This latest edition has been thoroughly revised, up-dated and expanded to give an in-depth coverage of the new developments in the field. Significant new material has been added to all the chapters and the applications section has been totally rewritten to ensure that topical and important applications are appropriately emphasised. The bibliography has been considerably enlarged to incorporate much valuable new information. Thus readers of the previous edition, which has established

  9. Waveform Analysis of UWB GPR Antennas

    Directory of Open Access Journals (Sweden)

    Julia Armesto

    2009-03-01

    Full Text Available Ground Penetrating Radar (GPR systems fall into the category of ultra-wideband (UWB devices. Most GPR equipment covers a frequency range between an octave and a decade by using short-time pulses. Each signal recorded by a GPR gathers a temporal log of attenuated and distorted versions of these pulses (due to the effect of the propagation medium plus possible electromagnetic interferences and noise. In order to make a good interpretation of this data and extract the most possible information during processing, a deep knowledge of the wavelet emitted by the antennas is essential. Moreover, some advanced processing techniques require specific knowledge of this signal to obtain satisfactory results. In this work, we carried out a series of tests in order to determine the source wavelet emitted by a ground-coupled antenna with a 500 MHz central frequency.

  10. Waveform Analysis of UWB GPR Antennas.

    Science.gov (United States)

    Rial, Fernando I; Lorenzo, Henrique; Pereira, Manuel; Armesto, Julia

    2009-01-01

    Ground Penetrating Radar (GPR) systems fall into the category of ultra-wideband (UWB) devices. Most GPR equipment covers a frequency range between an octave and a decade by using short-time pulses. Each signal recorded by a GPR gathers a temporal log of attenuated and distorted versions of these pulses (due to the effect of the propagation medium) plus possible electromagnetic interferences and noise. In order to make a good interpretation of this data and extract the most possible information during processing, a deep knowledge of the wavelet emitted by the antennas is essential. Moreover, some advanced processing techniques require specific knowledge of this signal to obtain satisfactory results. In this work, we carried out a series of tests in order to determine the source wavelet emitted by a ground-coupled antenna with a 500 MHz central frequency.

  11. 1998 Annual Study Report. Standardization of methods for evaluating characteristics of high-strength, large-diameter steel pipes for superhigh-pressure natural gas pipelines; 1998 nendo seika hokokusho. Chokoatsu tennen gas pipeline yo kokyodo daikei kokan no tokusei hoho no hyojunka

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The pipelines for safely transmitting superhigh-pressure natural gas should have excellent characteristics. The steel pipe is required to have a sufficient toughness, more concretely Charpy impact-absorbing energy, to prevent propagating shear fracture characteristic of natural gas pipelines. Recently, the natural gas pipeline is increasingly required to have higher design pressures (15 Mpa or higher) and grade (X80 or higher). In order to develop the techniques for simulating crack propagation in the propagating shear fracture of natural gas pipe lines as part of the programs to cope with these trends, the 1998 efforts were directed to reviewing the research results obtained so far and analysis of the problems to be solved and tasks to be taken, based on which the analytical procedure for gas releasing phenomena during the fracture process was basically developed, the material characteristic data were collected by the laboratory scale toughness tests, and the preliminary tests with rupture disks were conducted to verify the above analytical procedure. These efforts have established the bases for evaluating the characteristics of high-strength, large-diameter steel pipes in the light of safety against fracture, and greatly advanced the program towards the final target of developing the international specification drafts for toughness. (NEDO)

  12. OPTIMAL SIGNAL PROCESSING METHODS IN GPR

    Directory of Open Access Journals (Sweden)

    Saeid Karamzadeh

    2014-01-01

    Full Text Available In the past three decades, a lot of various applications of Ground Penetrating Radar (GPR took place in real life. There are important challenges of this radar in civil applications and also in military applications. In this paper, the fundamentals of GPR systems will be covered and three important signal processing methods (Wavelet Transform, Matched Filter and Hilbert Huang will be compared to each other in order to get most accurate information about objects which are in subsurface or behind the wall.

  13. Measuring the electrical properties of soil using a calibrated ground-coupled GPR system

    Science.gov (United States)

    Oden, C.P.; Olhoeft, G.R.; Wright, D.L.; Powers, M.H.

    2008-01-01

    Traditional methods for estimating vadose zone soil properties using ground penetrating radar (GPR) include measuring travel time, fitting diffraction hyperbolae, and other methods exploiting geometry. Additional processing techniques for estimating soil properties are possible with properly calibrated GPR systems. Such calibration using ground-coupled antennas must account for the effects of the shallow soil on the antenna's response, because changing soil properties result in a changing antenna response. A prototype GPR system using ground-coupled antennas was calibrated using laboratory measurements and numerical simulations of the GPR components. Two methods for estimating subsurface properties that utilize the calibrated response were developed. First, a new nonlinear inversion algorithm to estimate shallow soil properties under ground-coupled antennas was evaluated. Tests with synthetic data showed that the inversion algorithm is well behaved across the allowed range of soil properties. A preliminary field test gave encouraging results, with estimated soil property uncertainties (????) of ??1.9 and ??4.4 mS/m for the relative dielectric permittivity and the electrical conductivity, respectively. Next, a deconvolution method for estimating the properties of subsurface reflectors with known shapes (e.g., pipes or planar interfaces) was developed. This method uses scattering matrices to account for the response of subsurface reflectors. The deconvolution method was evaluated for use with noisy data using synthetic data. Results indicate that the deconvolution method requires reflected waves with a signal/noise ratio of about 10:1 or greater. When applied to field data with a signal/noise ratio of 2:1, the method was able to estimate the reflection coefficient and relative permittivity, but the large uncertainty in this estimate precluded inversion for conductivity. ?? Soil Science Society of America.

  14. CAPACITIVE TOMOGRAPHY FOR THE LOCATION OF PLASTIC PIPE

    Energy Technology Data Exchange (ETDEWEB)

    Brian J. Huber

    2003-07-29

    Throughout the utility industry, there is high interest in subsurface imaging of plastic, ceramic, and metallic objects because of the cost, reliability, and safety benefits available in avoiding impacts with the existing infrastructure and in reducing inappropriate excavations. Industry interest in locating plastic pipe has resulted in funding available for the development of technologies that enable this imaging. Gas Technology Institute (GTI) proposes to develop a compact and inexpensive capacitive tomography imaging sensor that takes the form of a flat plate or flexible mat that can be placed on the ground to image objects embedded in the soil. A compact, low-cost sensor that can image objects through soil could be applied to multiple operations and will produce a number of cost savings for the gas industry. In a stand-alone mode, it could be used to survey an area prior to excavation. The technology would improve the accuracy and reliability of any operation that involves excavation by locating or avoiding buried objects. An accurate subsurface image of an area will enable less costly keyhole excavations and other cost-saving techniques. Ground penetrating radar (GPR) has been applied to this area with limited success. Radar requires a high-frequency carrier to be injected into the soil: the higher the frequency, the greater the image resolution. Unfortunately, high-frequency radio waves are more readily absorbed by soil. Also, high-frequency operation raises the cost of the associated electronics. By contrast, the capacitive tomography sensor uses low frequencies with a multiple-element antenna to obtain good resolution. Low-frequency operation lowers the cost of the associated electronics while improving depth of penetration. The objective of this project is to combine several existing techniques in the area of capacitive sensing to quickly produce a demonstrable prototype. The sensor itself will take the form of a flat array of electrodes that can be

  15. Proposed systematic methodology for analysis of Pb-210 radioactivity in residues produced in Brazilian natural gas pipes; Proposicao de um modelo analitico sistematico da atividade de Pb-210 em residuos gerados em linhas de gas

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Aloisio Cordilha

    2003-11-15

    Since the 80's, the potential radiological hazards due to the handling of solid wastes contaminated with Rn-222 long-lived progeny - Pb-210 in special - produced in gas pipes and removed by pig operations have been subject of growing concern abroad our country. Nevertheless, little or no attention has been paid to this matter in the Brazilian plants up to now, being these hazards frequently underestimated or even ignored. The main purpose of this work was to propose a systematic methodology for analysis of Pb-210 radioactivity in black powder samples from some Brazilian plants, through the evaluation of direct Pb-210 gamma spectrometry and Bi-210 beta counting technical viabilities. In both cases, one in five samples of black powder analysed showed relevant activity (above 1Bq/kg) of Pb-210, being these results probably related to particular features of each specific plant (production levels, reservoir geochemical profile, etc.), in such a way that a single pattern is not observed. For the proposed methodology, gamma spectrometry proved to be the most reliable technique, showing a 3.5% standard deviation, and, for a 95% confidence level, overall fitness in the range of Pb-210 concentration of activity presented in the standard sample reference sheet, provided by IAEA for intercomparison purposes. In the Brazilian scene, however, the availability of statistically supported evidences is insufficient to allow the potential radiological hazard due to the management of black powder to be discarded. Thus, further research efforts are recommended in order to detect the eventually critical regions or plants where gas exploration, production and processing practices will require a regular program of radiological surveillance, in the near future. (author)

  16. Alteration of the glucagon axis in GPR120 (FFAR4) knockout mice: a role for GPR120 in glucagon secretion.

    Science.gov (United States)

    Suckow, Arthur T; Polidori, David; Yan, Wen; Chon, Suhyoun; Ma, Jing Ying; Leonard, James; Briscoe, Celia P

    2014-05-30

    GPR40 (FFAR1) and GPR120 (FFAR4) are G-protein-coupled receptors (GPCRs) that are activated by long chain fatty acids (LCFAs). GPR40 is expressed at high levels in islets and mediates the ability of LCFAs to potentiate glucose-stimulated insulin secretion (GSIS). GPR120 is expressed at high levels in colon, adipose, and pituitary, and at more modest levels in pancreatic islets. The role of GPR120 in islets has not been explored extensively. Here, we confirm that saturated (e.g. palmitic acid) and unsaturated (e.g. docosahexaenoic acid (DHA)) LCFAs engage GPR120 and demonstrate that palmitate- and DHA-potentiated glucagon secretion are greatly reduced in isolated GPR120 KO islets. Remarkably, LCFA potentiated glucagon secretion is similarly reduced in GPR40 KO islets. Compensatory changes in mRNA expression of GPR120 in GPR40 KO islets, and vice versa, do not explain that LCFA potentiated glucagon secretion seemingly involves both receptors. LCFA-potentiated GSIS remains intact in GPR120 KO islets. Consistent with previous reports, GPR120 KO mice are hyperglycemic and glucose intolerant; however, our KO mice display evidence of a hyperactive counter-regulatory response rather than insulin resistance during insulin tolerance tests. An arginine stimulation test and a glucagon challenge confirmed both increases in glucagon secretion and liver glucagon sensitivity in GPR120 KO mice relative to WT mice. Our findings demonstrate that GPR120 is a nutrient sensor that is activated endogenously by both saturated and unsaturated long chain fatty acids and that an altered glucagon axis likely contributes to the impaired glucose homeostasis observed in GPR120 KO mice. © 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

  17. CAPACITIVE TOMOGRAPHY FOR THE LOCATION OF PLASTIC PIPE

    International Nuclear Information System (INIS)

    Brian J. Huber; Christopher J. Ziolkowski

    2002-01-01

    Throughout the utility industry, there is high interest in subsurface imaging of plastic, ceramic, and metallic objects because of the cost, reliability, and safety benefits available in avoiding impacts with the existing infrastructure and in reducing inappropriate excavations. Industry interest in locating plastic pipe has resulted in funding available for the development of technologies that enable this imaging. Gas Technology Institute (GTI) proposes to develop a compact and inexpensive capacitive tomography imaging sensor that takes the form of a flat plate or flexible mat that can be placed on the ground to image objects embedded in the soil. A compact, low-cost sensor that can image objects through soil could be applied to multiple operations and will produce a number of cost savings for the gas industry. In a stand-alone mode, it could be used to survey an area prior to excavation. The technology would improve the accuracy and reliability of any operation that involves excavation by locating or avoiding buried objects. An accurate subsurface image of an area will enable less costly keyhole excavations and other cost-saving techniques. Ground penetrating radar (GPR) has been applied to this area with limited success. Radar requires a high-frequency carrier to be injected into the soil: the higher the frequency, the greater the image resolution. Unfortunately, high-frequency radio waves are more readily absorbed by soil. Also, high-frequency operation raises the cost of the associated electronics. By contrast, the capacitive tomography sensor uses low frequencies with a multiple-element antenna to obtain better resolution. Low-frequency operation lowers the cost of the associated electronics while improving depth of penetration. The objective of this project is to combine several existing techniques in the area of capacitive sensing to quickly produce a demonstrable prototype. The sensor itself will take the form of a flat array of electrodes that can be

  18. CAPACITIVE TOMOGRAPHY FOR THE LOCATION OF PLASTIC PIPE

    Energy Technology Data Exchange (ETDEWEB)

    Brian J. Huber; Christopher J. Ziolkowski

    2002-01-25

    Throughout the utility industry, there is high interest in subsurface imaging of plastic, ceramic, and metallic objects because of the cost, reliability, and safety benefits available in avoiding impacts with the existing infrastructure and in reducing inappropriate excavations. Industry interest in locating plastic pipe has resulted in funding available for the development of technologies that enable this imaging. Gas Technology Institute (GTI) proposes to develop a compact and inexpensive capacitive tomography imaging sensor that takes the form of a flat plate or flexible mat that can be placed on the ground to image objects embedded in the soil. A compact, low-cost sensor that can image objects through soil could be applied to multiple operations and will produce a number of cost savings for the gas industry. In a stand-alone mode, it could be used to survey an area prior to excavation. The technology would improve the accuracy and reliability of any operation that involves excavation by locating or avoiding buried objects. An accurate subsurface image of an area will enable less costly keyhole excavations and other cost-saving techniques. Ground penetrating radar (GPR) has been applied to this area with limited success. Radar requires a high-frequency carrier to be injected into the soil: the higher the frequency, the greater the image resolution. Unfortunately, high-frequency radio waves are more readily absorbed by soil. Also, high-frequency operation raises the cost of the associated electronics. By contrast, the capacitive tomography sensor uses low frequencies with a multiple-element antenna to obtain better resolution. Low-frequency operation lowers the cost of the associated electronics while improving depth of penetration. The objective of this project is to combine several existing techniques in the area of capacitive sensing to quickly produce a demonstrable prototype. The sensor itself will take the form of a flat array of electrodes that can be

  19. GPR Use and Activities in Denmark

    Science.gov (United States)

    Ringgaard, Jørgen; Wisén, Roger

    2014-05-01

    Academic work on GPR in Denmark is performed both by the Technical University of Denmark (DTU) and the University of Copenhagen (KU). The work at DTU includes development of antennas and systems, e.g. an airborne ice-sounder GPR system (POLARIS) that today is in frequent use for monitoring of ice thickness in Greenland. DTU often collaborates with ESA (European Space Agency) regarding electromagnetic development projects. At KU there is an ongoing work with GPR applied to water resources. The main objective is to study flux of water and matter across different hydrological domains. There are several recent publications from KU describing research for data analysis and modelling as well as hydro geophysical applications. Also the Geological Survey of Denmark and Greenland (GEUS) performs frequent geological mapping with GPR. There have been mainly two actors on the Danish commercial market for several years: FalkGeo and Ramboll. Falkgeo has been active for many years acquiring data for several different applications such as archeology, utilities and roads. Their equipment pool comprises both a multichannel Terravision system form GSSI and a 2D system from Mala Geoscience with a comprehensive range of antennas. Ramboll has performed GPR surveys for two decades mainly with 2D systems from GSSI. In recent years Ramboll has also obtained a system with RTA antennas from Mala Geoscience and a multichannel system from 3D-Radar. These systems have opened markets both for deeper geological mapping and for shallow mapping. The geological mapping with the Mala system has often been combined with resistivity imaging (CVES) and refraction seismic. The 3D system has been applied in airports and on road for mapping of layer thicknesses, delamination and for control of asphalt works. Other areas comprise bridge deck evaluation and utility mapping. Ramboll also acts as client advisor for BaneDanmark, a state owned company who operates and develops the Danish state railway network

  20. Shield For Flexible Pipe

    Science.gov (United States)

    Ponton, Michael K.; Williford, Clifford B.; Lagen, Nicholas T.

    1995-01-01

    Cylindrical shield designed to fit around flexible pipe to protect nearby workers from injury and equipment from damage if pipe ruptures. Designed as pressure-relief device. Absorbs impact of debris ejected radially from broken flexible pipe. Also redirects flow of pressurized fluid escaping from broken pipe onto flow path allowing for relief of pressure while minimizing potential for harm.

  1. Fundamentals of piping design

    CERN Document Server

    Smith, Peter

    2013-01-01

    Written for the piping engineer and designer in the field, this two-part series helps to fill a void in piping literature,since the Rip Weaver books of the '90s were taken out of print at the advent of the Computer Aid Design(CAD) era. Technology may have changed, however the fundamentals of piping rules still apply in the digitalrepresentation of process piping systems. The Fundamentals of Piping Design is an introduction to the designof piping systems, various processes and the layout of pipe work connecting the major items of equipment forthe new hire, the engineering student and the vetera

  2. Cannabidiol, a novel inverse agonist for GPR12.

    Science.gov (United States)

    Brown, Kevin J; Laun, Alyssa S; Song, Zhao-Hui

    2017-11-04

    GPR12 is a constitutively active, G s protein-coupled receptor that currently has no confirmed endogenous ligands. GPR12 may be involved in physiological processes such as maintenance of oocyte meiotic arrest and brain development, as well as pathological conditions such as metastatic cancer. In this study, the potential effects of various classes of cannabinoids on GPR12 were tested using a cAMP accumulation assay. Our data demonstrate that cannabidiol (CBD), a major non-psychoactive phytocannabinoid, acted as an inverse agonist to inhibit cAMP accumulation stimulated by the constitutively active GPR12. Thus, GPR12 is a novel molecular target for CBD. The structure-activity relationship studies of CBD indicate that both the free hydroxyl and the pentyl side chain are crucial for the effects of CBD on GPR12. Furthermore, studies using cholera toxin, which blocks G s protein and pertussis toxin, which blocks G i protein, revealed that G s , but not G i is involved in the inverse agonism of CBD on GPR12. CBD is a promising novel therapeutic agent for cancer, and GPR12 has been shown to alter viscoelasticity of metastatic cancer cells. Since we have demonstrated that CBD is an inverse agonist for GPR12, this provides novel mechanism of action for CBD, and an initial chemical scaffold upon which highly potent and efficacious agents acting on GPR12 may be developed with the ultimate goal of blocking cancer metastasis. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Insulated pipe clamp design

    International Nuclear Information System (INIS)

    Anderson, M.J.; Hyde, L.L.; Wagner, S.E.; Severud, L.K.

    1980-01-01

    Thin wall large diameter piping for breeder reactor plants can be subjected to significant thermal shocks during reactor scrams and other upset events. On the Fast Flux Test Facility, the addition of thick clamps directly on the piping was undesired because the differential metal temperatures between the pipe wall and the clamp could have significantly reduced the pipe thermal fatigue life cycle capabilities. Accordingly, an insulated pipe clamp design concept was developed. 5 refs

  4. Gas in Andean countries

    International Nuclear Information System (INIS)

    Campos Pinzon, Rafael

    2000-01-01

    The paper explores aspects of gas integration among Colombia, Venezuela, Ecuador and Peru. A comparison of the GDP is made, gas reserves are provided and the existent nets of gas-pipe are included in Colombia and Venezuela

  5. CAPACITIVE TOMOGRAPHY FOR THE LOCATION OF PLASTIC PIPE

    Energy Technology Data Exchange (ETDEWEB)

    Brian J. Huber

    2002-04-29

    Throughout the utility industry, there is high interest in subsurface imaging of plastic, ceramic, and metallic objects because of the cost, reliability, and safety benefits available in avoiding impacts with the existing infrastructure and in reducing inappropriate excavations. Industry interest in locating plastic pipe has resulted in funding available for the development of technologies that enable this imaging. Gas Technology Institute (GTI) proposes to develop a compact and inexpensive capacitive tomography imaging sensor that takes the form of a flat plate or flexible mat that can be placed on the ground to image objects embedded in the soil. A compact, low-cost sensor that can image objects through soil could be applied to multiple operations and will produce a number of cost savings for the gas industry. In a stand-alone mode, it could be used to survey an area prior to excavation. The technology would improve the accuracy and reliability of any operation that involves excavation by locating or avoiding buried objects. An accurate subsurface image of an area will enable less costly keyhole excavations and other cost-saving techniques. Ground penetrating radar (GPR) has been applied to this area with limited success. Radar requires a high-frequency carrier to be injected into the soil: the higher the frequency, the greater the image resolution. Unfortunately, high-frequency radio waves are more readily absorbed by soil. Also, high-frequency operation raises the cost of the associated electronics. By contrast, the capacitive tomography sensor uses low frequencies with a multiple-element antenna to obtain good resolution. Low-frequency operation lowers the cost of the associated electronics while improving depth of penetration. The objective of this project is to combine several existing techniques in the area of capacitive sensing to quickly produce a demonstrable prototype. The sensor itself will take the form of a flat array of electrodes that can be

  6. CAPACITIVE TOMOGRAPHY FOR THE LOCATION OF PLASTIC PIPE

    Energy Technology Data Exchange (ETDEWEB)

    Brian J. Huber

    2002-07-15

    Throughout the utility industry, there is high interest in subsurface imaging of plastic, ceramic, and metallic objects because of the cost, reliability, and safety benefits available in avoiding impacts with the existing infrastructure and in reducing inappropriate excavations. Industry interest in locating plastic pipe has resulted in funding available for the development of technologies that enable this imaging. Gas Technology Institute (GTI) proposes to develop a compact and inexpensive capacitive tomography imaging sensor that takes the form of a flat plate or flexible mat that can be placed on the ground to image objects embedded in the soil. A compact, low-cost sensor that can image objects through soil could be applied to multiple operations and will produce a number of cost savings for the gas industry. In a stand-alone mode, it could be used to survey an area prior to excavation. The technology would improve the accuracy and reliability of any operation that involves excavation by locating or avoiding buried objects. An accurate subsurface image of an area will enable less costly keyhole excavations and other cost-saving techniques. Ground penetrating radar (GPR) has been applied to this area with limited success. Radar requires a high-frequency carrier to be injected into the soil: the higher the frequency, the greater the image resolution. Unfortunately, high-frequency radio waves are more readily absorbed by soil. Also, high-frequency operation raises the cost of the associated electronics. By contrast, the capacitive tomography sensor uses low frequencies with a multiple-element antenna to obtain good resolution. Low-frequency operation lowers the cost of the associated electronics while improving depth of penetration. The objective of this project is to combine several existing techniques in the area of capacitive sensing to quickly produce a demonstrable prototype. The sensor itself will take the form of a flat array of electrodes that can be

  7. Insulated pipe clamp design

    International Nuclear Information System (INIS)

    Anderson, M.J.; Hyde, L.L.; Wagner, S.E.; Severud, L.K.

    1980-01-01

    Thin wall large diameter piping for breeder reactor plants can be subjected to significant thermal shocks during reactor scrams and other upset events. On the Fast Flux Test Facility, the addition of thick clamps directly on the piping was undesired because the differential metal temperatures between the pipe wall and the clamp could have significantly reduced the pipe thermal fatigue life cycle capabilities. Accordingly, an insulated pipe clamp design concept was developed. The design considerations and methods along with the development tests are presented. Special considerations to guard against adverse cracking of the insulation material, to maintain the clamp-pipe stiffness desired during a seismic event, to minimize clamp restraint on the pipe during normal pipe heatup, and to resist clamp rotation or spinning on the pipe are emphasized

  8. Piping Stress Analysis

    International Nuclear Information System (INIS)

    Setjo, Renaningsih

    2000-01-01

    Piping stress analysis on Primary Sampling System, Reactor Cooling System, and Feedwater System for AP600 have been performed. Piping stress analysis is one of the requirements in the design of piping system. Piping stress is occurred due to static and dynamic loads during service. Analysis was carried out. Using PS+CAEPIPE software based on the individual and combination loads with assumption that failure could be happened during normal, upset, emergency and faulted condition as describe in ASME III/ANSI B31.1. With performing the piping stress analysis, the layout (proper pipe routing) of the piping system can be design with the requirements of piping stress and pipe supports in mind I.e sufficient flexibility for thermal expansion, etc to commensurate with the i tended service such as temperatures, pressure, seismic and anticipated loading

  9. Flexible ocean upwelling pipe

    Science.gov (United States)

    Person, Abraham

    1980-01-01

    In an ocean thermal energy conversion facility, a cold water riser pipe is releasably supported at its upper end by the hull of the floating facility. The pipe is substantially vertical and has its lower end far below the hull above the ocean floor. The pipe is defined essentially entirely of a material which has a modulus of elasticity substantially less than that of steel, e.g., high density polyethylene, so that the pipe is flexible and compliant to rather than resistant to applied bending moments. The position of the lower end of the pipe relative to the hull is stabilized by a weight suspended below the lower end of the pipe on a flexible line. The pipe, apart from the weight, is positively buoyant. If support of the upper end of the pipe is released, the pipe sinks to the ocean floor, but is not damaged as the length of the line between the pipe and the weight is sufficient to allow the buoyant pipe to come to a stop within the line length after the weight contacts the ocean floor, and thereafter to float submerged above the ocean floor while moored to the ocean floor by the weight. The upper end of the pipe, while supported by the hull, communicates to a sump in the hull in which the water level is maintained below the ambient water level. The sump volume is sufficient to keep the pipe full during heaving of the hull, thereby preventing collapse of the pipe.

  10. Modelling of fiberglass pipe destruction process

    Directory of Open Access Journals (Sweden)

    А. К. Николаев

    2017-03-01

    Full Text Available The article deals with important current issue of oil and gas industry of using tubes made of high-strength composite corrosion resistant materials. In order to improve operational safety of industrial pipes it is feasible to use composite fiberglass tubes. More than half of the accidents at oil and gas sites happen at oil gathering systems due to high corrosiveness of pumped fluid. To reduce number of accidents and improve environmental protection we need to solve the issue of industrial pipes durability. This problem could be solved by using composite materials from fiberglass, which have required physical and mechanical properties for oil pipes. The durability and strength can be monitored by a fiberglass winding method, number of layers in composite material and high corrosion-resistance properties of fiberglass. Usage of high-strength composite materials in oil production is economically feasible; fiberglass pipes production is cheaper than steel pipes. Fiberglass has small volume weight, which simplifies pipe transportation and installation. In order to identify the efficiency of using high-strength composite materials at oil production sites we conducted a research of their physical-mechanical properties and modelled fiber pipe destruction process.

  11. Advanced Statistical Signal Processing Techniques for Landmine Detection Using GPR

    Science.gov (United States)

    2014-07-12

    Processing Techniques for Landmine Detection Using GPR The views, opinions and/or findings contained in this report are those of the author(s) and should not...310 Jesse Hall Columbia, MO 65211 -1230 654808 633606 ABSTRACT Advanced Statistical Signal Processing Techniques for Landmine Detection Using GPR Report...Aggregation Operator For Humanitarian Demining Using Hand- Held GPR , , (01 2008): . doi: D. Ho, P. Gader, J. Wilson, H. Frigui. Subspace Processing

  12. Online Dictionary Learning Aided Target Recognition In Cognitive GPR

    OpenAIRE

    Giovanneschi, Fabio; Mishra, Kumar Vijay; Gonzalez-Huici, Maria Antonia; Eldar, Yonina C.; Ender, Joachim H. G.

    2017-01-01

    Sparse decomposition of ground penetration radar (GPR) signals facilitates the use of compressed sensing techniques for faster data acquisition and enhanced feature extraction for target classification. In this paper, we investigate the application of an online dictionary learning (ODL) technique in the context of GPR to bring down the learning time as well as improve identification of abandoned anti-personnel landmines. Our experimental results using real data from an L-band GPR for PMN/PMA2...

  13. Pipe drafting and design

    CERN Document Server

    Parisher, Roy A; Parisher

    2000-01-01

    Pipe designers and drafters provide thousands of piping drawings used in the layout of industrial and other facilities. The layouts must comply with safety codes, government standards, client specifications, budget, and start-up date. Pipe Drafting and Design, Second Edition provides step-by-step instructions to walk pipe designers and drafters and students in Engineering Design Graphics and Engineering Technology through the creation of piping arrangement and isometric drawings using symbols for fittings, flanges, valves, and mechanical equipment. The book is appropriate primarily for pipe

  14. Experimental results from a stepped frequency GPR

    Directory of Open Access Journals (Sweden)

    G. M. Signore

    2003-06-01

    Full Text Available In the framework of a nationally funded project, a Ground Penetrating Radar (GPR has been developed by the Italian Consortium for Research on Advanced Remote Sensing Systems (CO.RI.S.T.A.. The system was described in a previous paper (Alberti et al., 2002. As new aspects, the system is a stepped frequency GPR that can work both in gated and ungated mode, and the antennas can be moved automatically in a controlled fashion. As aspects of geophysical interest, the system is exploitable in situations wherein a high resolution and a shallow penetration in the soil (a few meters are required. Possibly, this is an example of probing a landscape. This paper completes the results of Alberti et al. (2002, wherein laboratory tests where described, by providing the main results obtained during an outdoor experimental campaign, performed fi rst in a controlled site and then in an archaeological site.

  15. Signaling via G proteins mediates tumorigenic effects of GPR87

    DEFF Research Database (Denmark)

    Arfelt, Kristine Niss; Fares, Suzan; Sparre-Ulrich, Alexander H.

    2017-01-01

    G protein-coupled receptors (GPCRs) constitute a large protein family of seven transmembrane (7TM) spanning proteins that regulate multiple physiological functions. GPR87 is overexpressed in several cancers and plays a role in tumor cell survival. Here, the basal activity of GPR87 was investigated...... in transiently transfected HEK293 cells, revealing ligand-independent coupling to Gαi, Gαq and Gα12/13. Furthermore, GPR87 showed a ligand-independent G protein-dependent activation of the downstream transcription factors CREB, NFκB, NFAT and SRE. In tetracycline-induced Flp-In T-Rex-293 cells, GPR87 induced...

  16. Ground Penetrating Radar (GPR) for Detection of Underground Objects

    International Nuclear Information System (INIS)

    Amry Amin Abas; Mohd Kamal Shah Shamsuddin; Wan Zainal Abidin; Awang Sarfarudin Awang Putra

    2011-01-01

    Ground Penetrating Radar (GPR) utilizes an electromagnetic microwave that is transmitted into the matter under investigation. Any objects with different dielectric properties from the medium of the matter under investigation will reflect the waves and will be picked up by the receivers embedded in the antenna. We have applied GPR in various application such as concrete inspection, underground utility detection, grave detection, archaeology, oil contamination of soil, soil layer thickness measurement and etc. This paper will give general findings of the application of GPR to provide solutions to the industry and public. The results of the GPR surveys will be discussed. (author)

  17. Portuguese experience on the use of GPR

    Science.gov (United States)

    Fernandes, Francisco; Pais, Jorge; Gonçalves, Luísa

    2014-05-01

    Ground penetrating radar has been used for several decades in a wide range of applications, from pure research towards structural diagnostics and infrastructure survey. This method has proven to be very useful for fast and nondestructive quality check of structures, especially road pavements. Due to this fact, the use of this method is mandatory in a number of countries (United States, United Kingdom, Norway, etc.) before any digging operation or for the quality inspection of bituminous road beds, for example. In those countries, national guidelines exist to regulate the use of these equipments as well as rules and protocols to be followed by the professionals that provide those kinds of services. In Portugal, despite the advanced level of the structural engineering and construction professionals, and the existence of complex structures, the use of ground penetrating radar has exhibited a rather low penetration rate, comparatively to other European countries. This situation is due in part to the fact that GPR services are still more expensive than a more traditional way, which generally does not have the same degree of precision or implies the destruction of a part of the inspected area, and also because of the nature of Portuguese professionals. There is also a lack of national rules to regulate the use of GPR, which is the responsibility of ANACOM, as well as a certain lack of knowledge from national and regional authorities in order to make it mandatory in particular applications, namely in the case of intervention in the underground and road infrastructure. Despite this situation, GPR has been used in Portugal in recent years, although being mostly confined to the academic world. Thus, this communication presents several examples of the Portuguese experience on the use of GPR, which ranges from academic research towards structural and infrastructure inspection, to archaeological survey. This work is a contribution to COST Action TU1208 "Civil Engineering

  18. GPR measurements of attenuation in concrete

    Energy Technology Data Exchange (ETDEWEB)

    Eisenmann, David, E-mail: djeisen@cnde.iastate.edu; Margetan, Frank J., E-mail: djeisen@cnde.iastate.edu; Pavel, Brittney, E-mail: djeisen@cnde.iastate.edu [Center for Nondestructive Evaluation, Iowa State University, 1915 Scholl Road, Ames, IA 50011-3042 (United States)

    2015-03-31

    Ground-penetrating radar (GPR) signals from concrete structures are affected by several phenomenon, including: (1) transmission and reflection coefficients at interfaces; (2) the radiation patterns of the antenna(s) being used; and (3) the material properties of concrete and any embedded objects. In this paper we investigate different schemes for determining the electromagnetic (EM) attenuation of concrete from measured signals obtained using commercially-available GPR equipment. We adapt procedures commonly used in ultrasonic inspections where one compares the relative strengths of two or more signals having different travel paths through the material of interest. After correcting for beam spread (i.e., diffraction), interface phenomena, and equipment amplification settings, any remaining signal differences are assumed to be due to attenuation thus allowing the attenuation coefficient (say, in dB of loss per inch of travel) to be estimated. We begin with a brief overview of our approach, and then discuss how diffraction corrections were determined for our two 1.6 GHz GPR antennas. We then present results of attenuation measurements for two types of concrete using both pulse/echo and pitch/catch measurement setups.

  19. GPR measurements of attenuation in concrete

    International Nuclear Information System (INIS)

    Eisenmann, David; Margetan, Frank J.; Pavel, Brittney

    2015-01-01

    Ground-penetrating radar (GPR) signals from concrete structures are affected by several phenomenon, including: (1) transmission and reflection coefficients at interfaces; (2) the radiation patterns of the antenna(s) being used; and (3) the material properties of concrete and any embedded objects. In this paper we investigate different schemes for determining the electromagnetic (EM) attenuation of concrete from measured signals obtained using commercially-available GPR equipment. We adapt procedures commonly used in ultrasonic inspections where one compares the relative strengths of two or more signals having different travel paths through the material of interest. After correcting for beam spread (i.e., diffraction), interface phenomena, and equipment amplification settings, any remaining signal differences are assumed to be due to attenuation thus allowing the attenuation coefficient (say, in dB of loss per inch of travel) to be estimated. We begin with a brief overview of our approach, and then discuss how diffraction corrections were determined for our two 1.6 GHz GPR antennas. We then present results of attenuation measurements for two types of concrete using both pulse/echo and pitch/catch measurement setups

  20. Parametric study on thermal performance of horizontal earth pipe cooling system in summer

    International Nuclear Information System (INIS)

    Ahmed, S.F.; Amanullah, M.T.O.; Khan, M.M.K.; Rasul, M.G.; Hassan, N.M.S.

    2016-01-01

    Highlights: • Horizontal earth pipe cooling (HEPC) performance was investigated by a parametric study. • A thermal model was developed using FLUENT for the parametric study. • Air velocity, pipe length and pipe diameter showed noticeable impact on HEPC performance. • Pipe length greatly influenced the HEPC performance compared to other parameters. - Abstract: Rational use of energy and its associated greenhouse gas emissions has become a key issue for a sustainable environment and economy. A substantial amount of energy is consumed by today’s buildings which are accountable for about 40% of the global energy consumption. There are on-going researches in order to overcome these and find new techniques through energy efficient measures. Passive air cooling of earth pipe cooling technique is one of those which can save energy in buildings with no greenhouse gas emissions. The performance of the earth pipe cooling system is mainly affected by the parameters, namely air velocity, pipe length, pipe diameter, pipe material, and pipe depth. This paper investigates the impact of these parameters on thermal performance of the horizontal earth pipe cooling system in a hot humid subtropical climate at Rockhampton, Australia. For the parametric investigation, a thermal model was developed for the horizontal earth pipe cooling system using the simulation program, FLUENT 15.0. Results showed a significant effect for air velocity, pipe length, and pipe diameter on the earth pipe cooling performance, where the pipe length dominated the other parameters.

  1. E2GPR - Edit your geometry, Execute GprMax2D and Plot the Results!

    Science.gov (United States)

    Pirrone, Daniele; Pajewski, Lara

    2015-04-01

    In order to predict correctly the Ground Penetrating Radar (GPR) response from a particular scenario, Maxwell's equations have to be solved, subject to the physical and geometrical properties of the considered problem and to its initial conditions. Several techniques have been developed in computational electromagnetics, for the solution of Maxwell's equations. These methods can be classified into two main categories: differential and integral equation solvers, which can be implemented in the time or spectral domain. All of the different methods present compromises between computational efficiency, stability, and the ability to model complex geometries. The Finite-Difference Time-Domain (FDTD) technique has several advantages over alternative approaches: it has inherent simplicity, efficiency and conditional stability; it is suitable to treat impulsive behavior of the electromagnetic field and can provide either ultra-wideband temporal waveforms or the sinusoidal steady-state response at any frequency within the excitation spectrum; it is accurate and highly versatile; and it has become a mature and well-researched technique. Moreover, the FDTD technique is suitable to be executed on parallel-processing CPU-based computers and to exploit the modern computer visualisation capabilities. GprMax [1] is a very well-known and largely validated FDTD software tool, implemented by A. Giannopoulos and available for free public download on www.gprmax.com, together with examples and a detailled user guide. The tool includes two electromagnetic wave simulators, GprMax2D and GprMax3D, for the full-wave simulation of two-dimensional and three-dimensional GPR models. In GprMax, everything can be done with the aid of simple commands that are used to define the model parameters and results to be calculated. These commands need to be entered in a simple ASCII text file. GprMax output files can be stored in ASCII or binary format. The software is provided with MATLAB functions, which

  2. Assessment of highway pavements using GPR

    Science.gov (United States)

    Plati, Christina; Loizos, Andreas

    2015-04-01

    Highway infrastructure is a prerequisite for a functioning economy and social life. Highways, often prone to congestion and disruption, are one of the aspects of a modern transport network that require maximum efficiency if an integrated transport network, and sustainable mobility, is to be achieved. Assessing the condition of highway structures, to plan subsequent maintenance, is essential to allow the long-term functioning of a road network. Optimizing the methods used for such assessment will lead to better information being obtained about the road and underlying ground conditions. The condition of highway structures will be affected by a number of factors, including the properties of the highway pavement, the supporting sub-base and the subgrade (natural ground), and the ability to obtain good information about the entire road structure, from pavement to subgrade, allows appropriate maintenance programs to be planned. The maintenance of highway pavements causes considerable cost and in many cases obstruction to traffic flow. In this situation, methods that provide information on the present condition of pavement structure non-destructively and economically are of great interest. It has been shown that Ground-Penetrating-Radar (GPR), which is a Non Destructive Technique (NDT), can deliver information that is useful for the planning of pavement maintenance activities. More specifically GPR is used by pavement engineers in order to determine physical properties and characteristics of the pavement structure, information that is valuable for the assessment of pavement condition. This work gives an overview on the practical application of GPR using examples from highway asphalt pavements monitoring. The presented individual applications of GPR pavement diagnostics concern structure homogeneity, thickness of pavement layers, dielectric properties of asphalt materials etc. It is worthwhile mentioning that a number of applications are standard procedures, either

  3. Pipe-to-pipe impact program

    International Nuclear Information System (INIS)

    Alzheimer, J.M.; Bampton, M.C.C.; Friley, J.R.; Simonen, F.A.

    1984-06-01

    This report documents the tests and analyses performed as part of the Pipe-to-Pipe Impact (PTPI) Program at the Pacific Northwest Laboratory. This work was performed to assist the NRC in making licensing decisions regarding pipe-to-pipe impact events following postulated breaks in high energy fluid system piping. The report scope encompasses work conducted from the program's start through the completion of the initial hot oil tests. The test equipment, procedures, and results are described, as are analytic studies of failure potential and data correlation. Because the PTPI Program is only partially completed, the total significance of the current test results cannot yet be accurately assessed. Therefore, although trends in the data are discussed, final conclusions and recommendations will be possible only after the completion of the program, which is scheduled to end in FY 1984

  4. Investigation of HMA compactability using GPR technique

    Science.gov (United States)

    Plati, Christina; Georgiou, Panos; Loizos, Andreas

    2014-05-01

    In-situ field density is often regarded as one of the most important controls used to ensure that an asphalt pavement being placed is of high quality. The achieved density results from the effectiveness of the applied compaction mode on the Hot Mix Asphalt (HMA) layer. It is worthwhile mentioning that the proper compaction of HMA increases pavement fatigue life, decreases the amount of permanent deformation or rutting, reduces the amount of oxidation or aging, decreases moisture damage or stripping, increases strength and internal stability, and may decrease slightly the amount of low-temperature cracking that may occur in the mix. Conventionally, the HMA density in the field is assessed by direct destructive methods, including through the cutting of samples or drilling cores. These methods are characterized by a high accuracy, although they are intrusive and time consuming. In addition, they provide local information, i.e. information only for the exact test location. To overcome these limitations, the use of non-intrusive techniques is often recommended. The Ground Penetrating Radar (GPR) technique is an example of a non-intrusive technique that has been increasingly used for pavement investigations over the years. GPR technology is practical and application-oriented with the overall design concept, as well as the hardware, usually dependent on the target type and the material composing the target and its surroundings. As the sophistication of operating practices increases, the technology matures and GPR becomes an intelligent sensor system. The intelligent sensing deals with the expanded range of GPR applications in pavements such as determining layer thickness, detecting subsurface distresses, estimating moisture content, detecting voids and others. In addition, the practice of using GPR to predict in-situ field density of compacted asphalt mixture material is still under development and research; however the related research findings seem to be promising

  5. GPR Diagnostics of columns in archaeological contexts

    Science.gov (United States)

    Soldovieri, Francesco; Masini, Nicola; Persico, Raffaele; Catapano, Ilaria

    2017-04-01

    In the last decade the use of Ground Penetrating radar (GPR) applied to cultural heritage has been strongly increasing thanks to both technological development of sensors and softwares for data processing and cultural reasons such as the increasing awareness of conservators and archaeologist of the benefits of this method in terms of reduction of costs and time and risk associated with restoration works. This made GPR a mature technique for investigating different types of works of art and building elements of historical interest, including masonry structures, frescoes, mosaics [1-3], in the context of scientific projects, decision support activities aimed at the diagnosis of decay pathologies, and educational activities. One of the most complex building elements to be investigated by GPR are the columns both for the geometry of the object and for the several expected features to be detected including fractures, dishomogeneities and metallic connection elements. The work deals with the Ground Penetrating Radar diagnostic surveys at the prestigious archaeological site of Pompei. In particular, GPR surveys were carried out in two different areas, Palestra Grande and Tempio di Giove. The first campaign was carried out also as educational activity of the "International School "GEOPHYSICS AND REMOTE SENSING FOR ARCHAEOLOGY". The School aimed at giving the opportunity to scholars, PhD students, researchers and specialists in Geophysics, Remote Sensing and Archaeology to deepen their knowledge and expertise with geophysical and remote sensing techniques for archaeology and cultural heritage documentation and management. This survey was carried on two kinds of columns, with circular and rectangular section in order to detect possible hidden defects affecting their integrity. The second survey was carried out at Tempio di Giove, on request of the Soprintendenza Pompei, in order to gain information about the presence of reinforcement structures, which may be put inside the

  6. Design guideline to prevent the pipe rupture by radiolysis gases in BWR steam piping

    International Nuclear Information System (INIS)

    Inagaki, T.; Miyagawa, M.; Ota, T.; Sato, T.; Sakata, K.

    2009-01-01

    In late 2001, pipe rupture accidents due to fast combustion of radiolysis gas occurred in Japan and elsewhere's BWR power plants. TENPES began to set up the guideline as action to such a new problem to prevent accumulation and combustion of radiolysis gas in BWR steam piping. And then, the first edition of guideline was published in October 2005. Afterwards, the experimental study about combustion/detonation of radiolysis gas have been continued. And in March 2007, TENPES published a revised edition of the guideline. This is the report of the revised edition of that guideline. According to this guideline, it became possible to design BWR's steam piping to prevent accumulation of radiolysis gas. (author)

  7. Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation

    DEFF Research Database (Denmark)

    Dragano, Nathalia R V; Solon, Carina; Ramalho, Albina F

    2017-01-01

    BACKGROUND: The consumption of large amounts of dietary fats is one of the most important environmental factors contributing to the development of obesity and metabolic disorders. GPR120 and GPR40 are polyunsaturated fatty acid receptors that exert a number of systemic effects that are beneficial...

  8. GPR application on construction foundation study

    Science.gov (United States)

    Amran, T. S. T.; Ismail, M. P.; Ismail, M. A.; Amin, M. S. M.; Ahmad, M. R.; Basri, N. S. M.

    2017-11-01

    Extensive researches and studies have been carried on radar system for commercialisation of ground penetrating radar (GPR) technology pioneered in construction, and thus claimed its rightful place in the vision of future. The application of ground penetrating radar in construction study is briefly reviewed. Based on previous experimentation and studies, this paper is focus on reinforcement bar (rebar) investigation on construction. The various data through previous references used to discuss and analyse the capability of ground penetrating radar for further improvement in construction projects especially in rebar placement in works.

  9. GPR119 agonists: a promising approach for T2DM treatment? A SWOT analysis of GPR119.

    Science.gov (United States)

    Kang, Sang-Uk

    2013-12-01

    Ever since its advent as a promising therapeutic target for type 2 diabetes mellitus (T2DM), G-protein-coupled receptor 119 (GPR119) has received much interest from the pharmaceutical industry. This interest peaked in June 2010, when Sanofi-Aventis agreed to pay Metabolex (Cymabay Therapeutics) US$375 million for MBX-2982, which was a representative orally active GPR119 agonist. However, Sanofi-Aventis opted to terminate the deal in May 2011 and another leading GPR119 agonist, GSK1292263, had a loss of efficacy during its clinical trial. In this review, I discuss the pros and cons of GPR119 through a strengths, weaknesses, opportunities, and threats (SWOT) analysis and propose development strategies for the eventual success of a GPR119 agonist development program. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Uncertainty quantification of aeroacoustic power sources in corrugated pipes

    NARCIS (Netherlands)

    Swamy, M.; Shoeibi Omrani, P.; González Díez, N.

    2015-01-01

    Gas transport in corrugated pipes often exhibit whistling behavior, due to periodic flow-induced pulsations generated in the pipe cavities. These aero-acoustic sources are strongly dependent on the geometrical dimensions and features of the cavities. As a result, uncertainties in the exact shape and

  11. Geophysical characterization of peatlands using crosshole GPR full-waveform inversion: Case study from a bog in northwestern Germany

    Science.gov (United States)

    Schmäck, J.; Klotzsche, A.; Van Der Kruk, J.; Vereecken, H.; Bechtold, M.

    2017-12-01

    The characterization of peatlands is of particular interest, since areas with peat soils represent global hotspots for the exchange of greenhouse gases. Their effect on global warming depends on several parameters, like mean annual water level and land use. Models of greenhouse gas emissions and carbon accumulation in peatlands can be improved by including small-scale soil properties that e.g. act as gas traps and periodically release gases to the atmosphere during ebullition events. Ground penetrating radar (GPR) is well suited to non- or minimal invasively characterize and improve our understanding of dynamic processes that take place in the critical zone. It uses high frequency electromagnetic waves to image and characterize the dielectric permittivity and electrical conductivity of the critical zone, which can be related to hydrogeological properties like porosity, soil water content, salinity and clay content. In the last decade, the full-waveform inversion of crosshole GPR data has proved to be a powerful tool to improve the image resolution compared to standard ray-based methods. This approach was successfully applied to several different aquifers and was able to provide decimeter-scale resolution images including small-scale high contrast layers that can be related to zones of high porosity, zones of preferential flow or clay lenses. The comparison to independently measured e.g. logging data proved the reliability of the method. Here, for the first time crosshole GPR full-waveform inversion is used to image three peatland plots with different land use that are part of the "Ahlen-Falkenberger Moor peat bog complex" in northwestern Germany. The full-waveform inversion of the acquired data returned higher resolution images than standard ray-based GPR methods, and, is able to improve our understanding of subsurface structures. The comparison of the different plots is expected to provide new insights into gas content and gas trapping structures across different

  12. Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation.

    Science.gov (United States)

    Dragano, Nathalia R V; Solon, Carina; Ramalho, Albina F; de Moura, Rodrigo F; Razolli, Daniela S; Christiansen, Elisabeth; Azevedo, Carlos; Ulven, Trond; Velloso, Licio A

    2017-04-26

    The consumption of large amounts of dietary fats is one of the most important environmental factors contributing to the development of obesity and metabolic disorders. GPR120 and GPR40 are polyunsaturated fatty acid receptors that exert a number of systemic effects that are beneficial for metabolic and inflammatory diseases. Here, we evaluate the expression and potential role of hypothalamic GPR120 and GPR40 as targets for the treatment of obesity. Male Swiss (6-weeks old), were fed with a high fat diet (HFD, 60% of kcal from fat) for 4 weeks. Next, mice underwent stereotaxic surgery to place an indwelling cannula into the right lateral ventricle. intracerebroventricular (icv)-cannulated mice were treated twice a day for 6 days with 2.0 μL saline or GPR40 and GPR120 agonists: GW9508, TUG1197, or TUG905 (2.0 μL, 1.0 mM). Food intake and body mass were measured during the treatment period. At the end of the experiment, the hypothalamus was collected for real-time PCR analysis. We show that both receptors are expressed in the hypothalamus; GPR120 is primarily present in microglia, whereas GPR40 is expressed in neurons. Upon intracerebroventricular treatment, GW9508, a non-specific agonist for both receptors, reduced energy efficiency and the expression of inflammatory genes in the hypothalamus. Reducing GPR120 hypothalamic expression using a lentivirus-based approach resulted in the loss of the anti-inflammatory effect of GW9508 and increased energy efficiency. Intracerebroventricular treatment with the GPR120- and GPR40-specific agonists TUG1197 and TUG905, respectively, resulted in milder effects than those produced by GW9508. GPR120 and GPR40 act in concert in the hypothalamus to reduce energy efficiency and regulate the inflammation associated with obesity. The combined activation of both receptors in the hypothalamus results in better metabolic outcomes than the isolated activation of either receptor alone.

  13. 49 CFR 192.319 - Installation of pipe in a ditch.

    Science.gov (United States)

    2010-10-01

    ... NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS General Construction Requirements for..., except pipe in the Gulf of Mexico and its inlets under 15 feet (4.6 meters) of water, must be installed so that the top of the pipe is below the natural bottom unless the pipe is supported by stanchions...

  14. Burnable gas concentration control device

    International Nuclear Information System (INIS)

    Goto, Hiroshi; Sanada, Takahiro; Kuboniwa, Takao.

    1980-01-01

    Purpose: To provide connecting ports by doubling nitrogen gas injection pipes thereby to secure lengthiness of the device only by providing one nitrogen gas generator. Constitution: Nitrogen gas injection pipes are provided in two lines separately, and attachable and detachable connecting ports for feeding nitrogen gas connectable to a movable type nitrogen gas supply installation for the purpose of backing up the nitrogen gas generator. (Yoshihara, H.)

  15. GPR surveying of transport infrastructures and buildings; underground utility and void sensing - ongoing activities in Working Group 2 of COST Action TU1208

    Science.gov (United States)

    Pajewski, Lara; Plati, Christina; Derobert, Xavier

    2015-04-01

    areas.' Project 2.4 focuses on the development of 'Innovative procedures for effective GPR inspection of construction materials and structures.' The WG2 also includes Project 2.5 on the 'Determination, by using GPR, of the volumetric water content in structures, sub-structures, foundations and soil,' this is a topic of great interest in civil engineering, as water infiltration is often a relevant cause of degradation of structures, such as roads of bridges, and of rebar corrosion. During the first year of the Action, information was collected and shared about state-of-the-art, ongoing studies, problems and future research needs, in the topics covered by the five above-mentioned Projects [1-3]. Based on the experience and knowledge gained from the in-depth review work carried out by WG2, several case studies were then conducted; they were presented during the Second General Meeting and the GPR 2014 conference [5, 6]. Furthermore, the extension of GPR application to railways track ballast assessment was demonstrated [7]. The WG2 identified reference test-sites, suitable to compare inspection procedures or to test GPR equipment. The IFSTTAR geophysical test site is an open-air laboratory including a large and deep area, filled with various materials arranged in horisontal compacted slices, separated by vertical interfaces and water-tighted in surface; several objects as pipes, polystyrene hollows, boulders and masonry are embedded in the field [4]. The IFSTTAR full-scale APT facility is an outdoor circular carousel dedicated to full-scale pavement experiments, consisting of a central tower and four long arms equipped with wheels, running on a circular test track [4]. Furthermore, the WG2 is building a database of available experimental results, which are at the disposal of WG3 Members to test their electromagnetic modeling/inversion/data-processing methods. Another interesting and promising WG2 initiative that has to be mentioned is the development of a Catalogue of

  16. A thermal study of pipes with outer transverse fins

    Directory of Open Access Journals (Sweden)

    S. Gil

    2016-10-01

    Full Text Available This paper provides results of thermal investigations on pipes with outer transverse fins produced by placing a strip, being a form of helical spring which functions as a radiator, on the basis pipe. The investigations were carried out at the facility that enables measurements with respect to both natural and forced convection. Performance of the investigated pipes was assessed in relation to a non-finned pipe and a pipe welded with the use of Metal Active Gas (MAG technology. The experiments have shown that the finned pipe welding technology does not markedly affect their thermal efficiency, which has been confirmed by performed model calculations, while the welding technology has a crucial impact on their operating performance.

  17. Design of a cavity heat pipe receiver experiment

    Science.gov (United States)

    Schneider, Michael G.; Brege, Mark H.; Greenlee, William J.

    1992-01-01

    A cavity heat pipe experiment has been designed to test the critical issues involved with incorporating thermal energy storage canisters into a heat pipe. The experiment is a replication of the operation of a heat receiver for a Brayton solar dynamic power cycle. The heat receiver is composed of a cylindrical receptor surface and an annular heat pipe with thermal energy storage canisters and gaseous working fluid heat exchanger tubes surrounding it. Hardware for the cavity heat pipe experiment will consist of a sector of the heat pipe, complete with gas tube and thermal energy storage canisters. Thermal cycling tests will be performed on the heat pipe sector to simulate the normal energy charge/discharge cycle of the receiver in a spacecraft application.

  18. Analysis and Optimisation of Carcass Production for Flexible Pipes

    DEFF Research Database (Denmark)

    Nielsen, Peter Søe

    Un-bonded flexible pipes are used in the offshore oil and gas industry worldwide transporting hydrocarbons from seafloor to floating production vessels topside. Flexible pipes are advantageous over rigid pipelines in dynamic applications and during installation as they are delivered in full length...... on reels. Flexible pipes are constructed in a layer structure in which each layer adds specific properties to the pipe such as; collapse strength, fluid integrity, bursting strength, tensile strength etc. The inner-most layer of a flexible pipe is the carcass; a flexible interlocking stainless steel...... structure that provides mechanical and collapse strength for the flexible pipe. The manufacturing process of carcass is a combination of roll forming stainless steel strips and helical winding the profiles around a mandrel interlocking the profiles with themselves. The focus of the present project...

  19. Introduction to Heat Pipes

    Science.gov (United States)

    Ku, Jentung

    2015-01-01

    This is the presentation file for the short course Introduction to Heat Pipes, to be conducted at the 2015 Thermal Fluids and Analysis Workshop, August 3-7, 2015, Silver Spring, Maryland. NCTS 21070-15. Course Description: This course will present operating principles of the heat pipe with emphases on the underlying physical processes and requirements of pressure and energy balance. Performance characterizations and design considerations of the heat pipe will be highlighted. Guidelines for thermal engineers in the selection of heat pipes as part of the spacecraft thermal control system, testing methodology, and analytical modeling will also be discussed.

  20. Piping engineering and operation

    International Nuclear Information System (INIS)

    1993-01-01

    The conference 'Piping Engineering and Operation' was organized by the Institution of Mechanical Engineers in November/December 1993 to follow on from similar successful events of 1985 and 1989, which were attended by representatives from all sectors of the piping industry. Development of engineering and operation of piping systems in all aspects, including non-metallic materials, are highlighted. The range of issues covered represents a balance between current practices and implementation of future international standards. Twenty papers are printed. Two, which are concerned with pressurized pipes or steam lines in the nuclear industry, are indexed separately. (Author)

  1. Targeting GPR110 in HER2-Overexpressing Breast Cancers

    Science.gov (United States)

    2015-10-01

    results showed that GPR110 expression was higher in at least one of the resistant models 3   (LR, TR, or LTR) in 4 out of 9 models of BT474, SKBR3 ...LTR derivatives of 3 models (BT474, SKBR3 , and UACC812) compared to the parental cells (Figure 2A-C). In the AU565 and HCC202 models, GPR110 mRNA...2015). Based on the GPR110 expression, 2 cell line models (BT474 and SKBR3 ) have been selected for generation of stable cell lines capable of

  2. GPR-Based Water Leak Models in Water Distribution Systems

    Science.gov (United States)

    Ayala-Cabrera, David; Herrera, Manuel; Izquierdo, Joaquín; Ocaña-Levario, Silvia J.; Pérez-García, Rafael

    2013-01-01

    This paper addresses the problem of leakage in water distribution systems through the use of ground penetrating radar (GPR) as a nondestructive method. Laboratory tests are performed to extract features of water leakage from the obtained GPR images. Moreover, a test in a real-world urban system under real conditions is performed. Feature extraction is performed by interpreting GPR images with the support of a pre-processing methodology based on an appropriate combination of statistical methods and multi-agent systems. The results of these tests are presented, interpreted, analyzed and discussed in this paper.

  3. GPR-Based Water Leak Models in Water Distribution Systems

    Directory of Open Access Journals (Sweden)

    David Ayala–Cabrera

    2013-11-01

    Full Text Available This paper addresses the problem of leakage in water distribution systems through the use of ground penetrating radar (GPR as a nondestructive method. Laboratory tests are performed to extract features of water leakage from the obtained GPR images. Moreover, a test in a real-world urban system under real conditions is performed. Feature extraction is performed by interpreting GPR images with the support of a pre-processing methodology based on an appropriate combination of statistical methods and multi-agent systems. The results of these tests are presented, interpreted, analyzed and discussed in this paper.

  4. 46 CFR 76.15-15 - Piping.

    Science.gov (United States)

    2010-10-01

    ... or other openings within such spaces. (j) Installation test requirements: (1) Upon completion of the piping installation, and before the cylinders are connected, a pressure test shall be applied as set forth in this paragraph. Only carbon dioxide or other inert gas shall be used for this test. (2) The...

  5. Field investigation on structural performance of the buried UPVC pipes with and without geogrid reinforcement

    Science.gov (United States)

    Teja, Akkineni Surya; Rajkumar, R.; Gokula Krishnan, B.; Aravindh, R.

    2018-02-01

    Buried pipes are used mainly for water supply and drainage besides many other applications such as oil, liquefied natural gas, coal slurries and mine tailings. The pipes used may be rigid (reinforced concrete, vitrified clay and ductile iron) or flexible (Steel, UPVC, aluminium, Fiber glass and High-density polyethylene) although the distinction between them is blurring. Flexible pipe design is governed by deflection or buckling. UPVC pipes are preferred due to light weight, long term chemical stability and cost efficiency. This project aims to study the load deformation behaviour of the buried pipe and stress variation across the cross section of the pipe under static loading along with the influence of depth of embedment, density of backfill on the deformation and stresses in pipe and the deformation behaviour of buried pipe when soil is reinforced with geogrid reinforcement and evaluate the structural performance of the pipe.

  6. 77 FR 13079 - Certain Large Diameter Carbon and Alloy Seamless Standard, Line, and Pressure Pipe (Over 41/2

    Science.gov (United States)

    2012-03-05

    ... natural gas or other fluids in pipe lines. Seamless line pipes are produced to the API 5L specification... comments on a computer diskette. Case and rebuttal briefs must be served on interested parties in...

  7. Hot Leg Piping Materials Issues

    International Nuclear Information System (INIS)

    V. Munne

    2006-01-01

    With Naval Reactors (NR) approval of the Naval Reactors Prime Contractor Team (NRPCT) recommendation to develop a gas cooled reactor directly coupled to a Brayton power conversion system as the space nuclear power plant (SNPP) for Project Prometheus (References a and b) the reactor outlet piping was recognized to require a design that utilizes internal insulation (Reference c). The initial pipe design suggested ceramic fiber blanket as the insulation material based on requirements associated with service temperature capability within the expected range, very low thermal conductivity, and low density. Nevertheless, it was not considered to be well suited for internal insulation use because its very high surface area and proclivity for holding adsorbed gases, especially water, would make outgassing a source of contaminant gases in the He-Xe working fluid. Additionally, ceramic fiber blanket insulating materials become very friable after relatively short service periods at working temperatures and small pieces of fiber could be dislodged and contaminate the system. Consequently, alternative insulation materials were sought that would have comparable thermal properties and density but superior structural integrity and greatly reduced outgassing. This letter provides technical information regarding insulation and materials issues for the Hot Leg Piping preconceptual design developed for the Project Prometheus space nuclear power plant (SNPP)

  8. Heat Pipe with Axial Wick

    Science.gov (United States)

    Ambrose, Jay H. (Inventor); Holmes, Rolland (Inventor)

    2016-01-01

    A heat pipe has an evaporator portion, a condenser portion, and at least one flexible portion that is sealingly coupled between the evaporator portion and the condenser portion. The flexible portion has a flexible tube and a flexible separator plate held in place within the flexible tube so as to divide the flexible tube into a gas-phase passage and a liquid-phase artery. The separator plate and flexible tube are configured such that the flexible portion is flexible in a plane that is perpendicular to the separator plate.

  9. Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81)

    DEFF Research Database (Denmark)

    Jeninga, Ellen H; Bugge, Anne Skovsø; Nielsen, Ronni

    2009-01-01

    target genes that may contribute to the reduction of circulating free fatty acids after TZD treatment have been identified, the relevant PPARgamma target genes that may exert the anti-lipolytic effect of TZDs are unknown. Here we identified the anti-lipolytic human G-protein-coupled receptor 81 (GPR81......), GPR109A, and the (human-specific) GPR109B genes as well as the mouse Gpr81 and Gpr109A genes as novel TZD-induced genes in mature adipocytes. GPR81/Gpr81 is a direct PPARgamma target gene, because mRNA expression of GPR81/Gpr81 (and GPR109A/Gpr109A) increased in mature human and murine adipocytes...... as well as in vivo in epididymal fat pads of mice upon rosiglitazone stimulation, whereas small interfering RNA-mediated knockdown of PPARgamma in differentiated 3T3-L1 adipocytes showed a significant decrease in Gpr81 protein expression. In addition, chromatin immunoprecipitation sequencing analysis...

  10. Ground penetrating radar (GPR) analysis : Phase II field evaluation.

    Science.gov (United States)

    2011-10-01

    "The objective of this work was to evaluate the feasibility and value of expanding the MDT's Ground : Penetrating Radar (GPR) program to pavement design and rehabilitation, and to network level : evaluation. Phase I of this project concluded that in ...

  11. A Forward-Looking High-Resolution GPR System

    National Research Council Canada - National Science Library

    Kositsky, Joel; Milanfar, Peyman

    1999-01-01

    A high-resolution ground penetrating radar (GPR) system was designed to help define the optimal radar parameters needed for the efficient standoff detection of buried and surface-laid antitank mines...

  12. Studies on the application of GPR in OSI for CTBT

    International Nuclear Information System (INIS)

    Li Chuanying; Feng Diqing

    1999-01-01

    Based on the fundamental techniques and characteristics of GPR (ground penetrating radar) the feasibility and limitation of its usage in OSI (on site inspection) are discussed, and a referential conclusion is given

  13. Piping research program plan

    International Nuclear Information System (INIS)

    1988-09-01

    This document presents the piping research program plan for the Structural and Seismic Engineering Branch and the Materials Engineering Branch of the Division of Engineering, Office of Nuclear Regulatory Research. The plan describes the research to be performed in the areas of piping design criteria, environmentally assisted cracking, pipe fracture, and leak detection and leak rate estimation. The piping research program addresses the regulatory issues regarding piping design and piping integrity facing the NRC today and in the foreseeable future. The plan discusses the regulatory issues and needs for the research, the objectives, key aspects, and schedule for each research project, or group of projects focussing of a specific topic, and, finally, the integration of the research areas into the regulatory process is described. The plan presents a snap-shot of the piping research program as it exists today. However, the program plan will change as the regulatory issues and needs change. Consequently, this document will be revised on a bi-annual basis to reflect the changes in the piping research program. (author)

  14. Holographic bulk viscosity: GPR vs EO

    CERN Document Server

    Buchel, Alex; Kiritsis, Elias

    2011-01-01

    Recently Eling and Oz (EO) proposed a formula for the holographic bulk viscosity, in arXiv:1103.1657, derived from the null horizon focusing equation. This formula seems different from that obtained earlier by Gubser, Pufu and Rocha (GPR) in arXiv:0806.0407 calculated from the IR limit of the two-point function of the trace of the stress tensor. The two were shown to agree only for some simple scaling cases. We point out that the two formulae agree in two non-trivial holographic theories describing RG flows. The first is the strongly coupled N=2* gauge theory plasma. The second is the semi-phenomenological model of Improved Holographic QCD.

  15. 75 FR 13644 - TORP Terminal LP, Bienville Offshore Energy Terminal Liquefied Natural Gas Deepwater Port License...

    Science.gov (United States)

    2010-03-22

    ... unit would regasify the LNG and deliver the gas via flexible gas pipes to the floating regasification... unit, two mooring lines that connect the HiLoad to the FRU, two high pressure (HP) flexible gas pipes...

  16. Surface-based GPR underestimates below-stump root biomass

    Science.gov (United States)

    John R. Butnor; Lisa J. Samuelson; Thomas A. Stokes; Kurt H. Johnsen; Peter H. Anderson; Carlos A. Gonzalez-Benecke

    2016-01-01

    Aims While lateral root mass is readily detectable with ground penetrating radar (GPR), the roots beneath a tree (below-stump) and overlapping lateral roots near large trees are problematic for surface-based antennas operated in reflection mode. We sought to determine if tree size (DBH) effects GPR root detection proximal to longleaf pine (Pinus palustris Mill) and if...

  17. Oscillating heat pipes

    CERN Document Server

    Ma, Hongbin

    2015-01-01

    This book presents the fundamental fluid flow and heat transfer principles occurring in oscillating heat pipes and also provides updated developments and recent innovations in research and applications of heat pipes. Starting with fundamental presentation of heat pipes, the focus is on oscillating motions and its heat transfer enhancement in a two-phase heat transfer system. The book covers thermodynamic analysis, interfacial phenomenon, thin film evaporation,  theoretical models of oscillating motion and heat transfer of single phase and two-phase flows, primary  factors affecting oscillating motions and heat transfer,  neutron imaging study of oscillating motions in an oscillating heat pipes, and nanofluid’s effect on the heat transfer performance in oscillating heat pipes.  The importance of thermally-excited oscillating motion combined with phase change heat transfer to a wide variety of applications is emphasized. This book is an essential resource and learning tool for senior undergraduate, gradua...

  18. Improvement activities to soil stabilization near Bolivia-Brazil gas pipeline crossing through an embankment over a corrugated drainage pipe, at Km 247 in Mato Grosso do Sul, Brazil; Melhorias para estabilidade do gasoduto Bolivia-Brasil em cruzamento de aterro sobre tubo de drenagem tipo ARMCO, no km 247 em Mato Grosso do Sul

    Energy Technology Data Exchange (ETDEWEB)

    Jorge, Kemal Vieira [TBG - Transportadora Brasileira Gasoduto Bolivia Brasil S.A., Rio de Janeiro, RJ (Brazil); Costa, Cesar Augusto [TBG - Transportadora Brasileira Gasoduto Bolivia Brasil S.A., Campo Grande, MS (Brazil). Gerencia Regional Centro Oeste (CRGO)

    2005-07-01

    A hundred and seventy kilometers from Campo Grande city, on Mato Grosso do Sul State, the Brasil-Bolivia Gas Pipeline crosses a 8,5 meters high landfill, over a drainage systems made of a 2,8 meters of diameter corrugated pipe. This drainage pipe was installed to allow the drainage of the valley, and the landfill above it was built so the Gas pipeline could cross easier the 80 meters deep and 30 degree vertices valley. This paper illustrates the work tasks and solutions taken to monitor and guarantee the integrity of the drainage and landfill structures, as well as the integrity of the Gas Pipeline. Some of the work tasks illustrated are the investigation of the support conditions of the Gas Pipeline, the analysis of a drainage system under the pipeline, on a rocky soil, the analysis of the stability of the landfill, the construction of a gravity retaining walls and the monitoring of the deformations on the drainage pipe. (author)

  19. GPR 120: The Potential Target for Obesity Treatment.

    Science.gov (United States)

    Tanagho, Peter A; Shohdy, Kyrillus S

    2016-01-01

    G protein coupled receptor 120 (GPR120) is a class of receptors in the gastrointestinal tract (GIT) that is implicated in nutrient sensing and body weight regulation. Functions of GPR120 are thought to be mediated by the release of a group of hormones known as incretins, such as glucagon like peptide 1 (GLP-1) and gastric inhibitory polypeptide (GIP). We have searched PubMed with the keywords "GPR120","GLP-1" and "obesity". Relevant studies were retrieved and included in the review. Recently, many exogenous compounds have been investigated in their role in the release of GLP-1 and in causing weight loss in obese rats. However, some results question the putative role of GPR120 in metabolic homeostasis. Herein, we evaluate the potential use of GPR120 as a target receptor in obesity and found it to be ubiquitous throughout the GIT, with various functions in each site. In order to find the optimal drug, the role of GPR120 in each site needs to be defined and selectivity of the potential drug needs to be studied to ensure the success of this growing line of obesity management.

  20. Estimation of Hydraulic Property of an Unconfined Aquifer by GPR

    Science.gov (United States)

    Lu, Qi; Sato, Motoyuki

    2007-06-01

    Controlled water productions were performed at a water source area of Ulaanbaatar city, Mongolia to evaluate the effectiveness of ground penetrating radar (GPR) for detecting and monitoring dynamic groundwater movements in the subsurface and for estimating the hydraulic properties of the aquifer. Field experiments in Ulaanbaatar were carried out in 2001 and 2002. GPR data were acquired using 100 MHz antennas. This paper reports the results of GPR methods to monitor the groundwater migration caused by the pumping operation and GPR’s potential ability to estimate hydraulic properties of the aquifer. The GPR data sets were acquired very carefully by locating the antenna position accurately. The residual trace shows a feature that is a combination of the water level reflections acquired at two different times in the pumping test. It helped to determine travel time and its effective reflection point from the top of the water saturated zone. The residual wavelet varies versus offset from the pumping well for a given residual image. Common midpoint (CMP) data and velocity analysis indicated the depth of the water table and the water content in the unsaturated and saturated zone. Combining hydrogeologic data with quantitative information yielded by GPR data, hydraulic properties of the aquifer could be estimated by assuming a hydraulic model. It was concluded that GPR can be successfully employed to monitor groundwater migration and to estimate hydraulic properties of the aquifer.

  1. ONKALO EDZ-measurements using ground penetrating radar (GPR) method

    International Nuclear Information System (INIS)

    Silvast, M.; Wiljanen, B.

    2008-09-01

    This report presents pilot project results from various Ground Penetrating Radar (GPR) tests performed on bedrock in ONKALO, the research tunnel system being built for the final disposal of spent nuclear fuel (in Finland). In recent years the GPR technology for structure inspection has improved to faster systems and higher frequencies. Processing and interpretation software has been developed for better visualization of processed data. GPR is a powerful non-destructive testing method with major advantages such as fast measurement speed and continuous survey lines. The purpose of the tests was to determine the capacity of GPR in identifying the Excavation Damaged or Disturbed Zone (EDZ). Topics included comparison of different types of GPR systems and antennas in select locations in the tunnel system and data presentation. High quality GPR data was obtained from all systems that were used on surfaces without concrete or steel reinforcement. Data processed using Geo Doctor software, which enables integrated analysis of available datasets on a single screen, provided promising results. (orig.)

  2. Soluble Fibre Meal Challenge Reduces Airway Inflammation and Expression of GPR43 and GPR41 in Asthma

    Directory of Open Access Journals (Sweden)

    Isabel Halnes

    2017-01-01

    Full Text Available Short chain fatty acids (SCFAs are produced following the fermentation of soluble fibre by gut bacteria. In animal models, both dietary fibre and SCFAs have demonstrated anti-inflammatory effects via the activation of free fatty acid receptors, such as G protein-coupled receptor 41 and 43 (GPR41 and GPR43. This pilot study examined the acute effect of a single dose of soluble fibre on airway inflammation—including changes in gene expression of free fatty acid receptors—in asthma. Adults with stable asthma consumed a soluble fibre meal (n = 17 containing 3.5 g inulin and probiotics, or a control meal (n = 12 of simple carbohydrates. Exhaled nitric oxide (eNO was measured and induced sputum was collected at 0 and 4 h for differential cell counts, measurement of interleukin-8 (IL-8 protein concentration, and GPR41 and GPR43 gene expression. At 4 h after meal consumption, airway inflammation biomarkers, including sputum total cell count, neutrophils, macrophages, lymphocytes, sputum IL-8, and eNO significantly decreased compared to baseline in the soluble fibre group only. This corresponded with upregulated GPR41 and GPR43 sputum gene expression and improved lung function in the soluble fibre group alone. Soluble fibre has acute anti-inflammatory effects in asthmatic airways. Long-term effects of soluble fibre as an anti-inflammatory therapy in asthma warrants further investigation.

  3. Soluble Fibre Meal Challenge Reduces Airway Inflammation and Expression of GPR43 and GPR41 in Asthma

    Science.gov (United States)

    Halnes, Isabel; Baines, Katherine J.; Berthon, Bronwyn S.; MacDonald-Wicks, Lesley K.; Gibson, Peter G.; Wood, Lisa G.

    2017-01-01

    Short chain fatty acids (SCFAs) are produced following the fermentation of soluble fibre by gut bacteria. In animal models, both dietary fibre and SCFAs have demonstrated anti-inflammatory effects via the activation of free fatty acid receptors, such as G protein-coupled receptor 41 and 43 (GPR41 and GPR43). This pilot study examined the acute effect of a single dose of soluble fibre on airway inflammation—including changes in gene expression of free fatty acid receptors—in asthma. Adults with stable asthma consumed a soluble fibre meal (n = 17) containing 3.5 g inulin and probiotics, or a control meal (n = 12) of simple carbohydrates. Exhaled nitric oxide (eNO) was measured and induced sputum was collected at 0 and 4 h for differential cell counts, measurement of interleukin-8 (IL-8) protein concentration, and GPR41 and GPR43 gene expression. At 4 h after meal consumption, airway inflammation biomarkers, including sputum total cell count, neutrophils, macrophages, lymphocytes, sputum IL-8, and eNO significantly decreased compared to baseline in the soluble fibre group only. This corresponded with upregulated GPR41 and GPR43 sputum gene expression and improved lung function in the soluble fibre group alone. Soluble fibre has acute anti-inflammatory effects in asthmatic airways. Long-term effects of soluble fibre as an anti-inflammatory therapy in asthma warrants further investigation. PMID:28075383

  4. GPR18 Controls Reconstitution of Mouse Small Intestine Intraepithelial Lymphocytes following Bone Marrow Transplantation.

    Directory of Open Access Journals (Sweden)

    Amy M Becker

    Full Text Available Specific G protein coupled receptors (GPRs regulate the proper positioning, function, and development of immune lineage subsets. Here, we demonstrate that GPR18 regulates the reconstitution of intraepithelial lymphocytes (IELs of the small intestine following bone marrow transplantation. Through analysis of transcriptional microarray data, we find that GPR18 is highly expressed in IELs, lymphoid progenitors, and mature follicular B cells. To establish the physiological role of this largely uncharacterized GPR, we generated Gpr18-/- mice. Despite high levels of GPR18 expression in specific hematopoietic progenitors, Gpr18-/- mice have no defects in lymphopoiesis or myelopoiesis. Moreover, antibody responses following immunization with hapten-protein conjugates or infection with West Nile virus are normal in Gpr18-/- mice. Steady-state numbers of IELs are also normal in Gpr18-/- mice. However, competitive bone marrow reconstitution experiments demonstrate that GPR18 is cell-intrinsically required for the optimal restoration of small intestine TCRγδ+ and TCRαβ+ CD8αα+ IELs. In contrast, GPR18 is dispensable for the reconstitution of large intestine IELs. Moreover, Gpr18-/- bone marrow reconstitutes small intestine IELs similarly to controls in athymic recipients. Gpr18-/- chimeras show no changes in susceptibility to intestinal insults such as Citrobacter rodentium infections or graft versus host disease. These data reveal highly specific requirements for GPR18 in the development and reconstitution of thymus-derived intestinal IEL subsets in the steady-state and after bone marrow transplantation.

  5. Pipe drafting and design

    CERN Document Server

    Parisher, Roy A

    2011-01-01

    Pipe Drafting and Design, Third Edition provides step-by-step instructions to walk pipe designers, drafters, and students through the creation of piping arrangement and isometric drawings. It includes instructions for the proper drawing of symbols for fittings, flanges, valves, and mechanical equipment. More than 350 illustrations and photographs provide examples and visual instructions. A unique feature is the systematic arrangement of drawings that begins with the layout of the structural foundations of a facility and continues through to the development of a 3-D model. Advanced chapters

  6. Flexible ultrasonic pipe inspection apparatus

    Energy Technology Data Exchange (ETDEWEB)

    Jenkins, C.F.; Howard, B.D.

    1994-01-01

    Pipe crawlers, pipe inspection {open_quotes}rabbits{close_quotes} and similar vehicles are widely used for inspecting the interior surfaces of piping systems, storage tanks and process vessels for damaged or flawed structural features. This paper describes the design of a flexible, modular ultrasonic pipe inspection apparatus.

  7. Improved Thin, Flexible Heat Pipes

    Science.gov (United States)

    Rosenfeld, John H.; Gernert, Nelson J.; Sarraf, David B.; Wollen, Peter J.; Surina, Frank C.; Fale, John E.

    2004-01-01

    Flexible heat pipes of an improved type are fabricated as layers of different materials laminated together into vacuum- tight sheets or tapes. In comparison with prior flexible heat pipes, these flexible heat pipes are less susceptible to leakage. Other advantages of these flexible heat pipes, relative to prior flexible heat pipes, include high reliability and greater ease and lower cost of fabrication. Because these heat pipes are very thin, they are highly flexible. When coated on outside surfaces with adhesives, these flexible heat pipes can be applied, like common adhesive tapes, to the surfaces of heat sinks and objects to be cooled, even if those surfaces are curved.

  8. Valve for the mechanical isolation of a pipe to take up a test probe

    International Nuclear Information System (INIS)

    Uecker, D.F.

    1976-01-01

    A valve is introduced for application in a pipe in which a test probe is arranged. The valve serves to isolate the pipe in a gas-tight way, thus preventing the escape of radioactive gas or dust during operation in a nuclear reactor. (TK) [de

  9. Gas

    International Nuclear Information System (INIS)

    1996-01-01

    The French government has decided to modify the conditions of extension of local natural gas authorities to neighbouring districts. The European Union is studying the conditions of internal gas market with the objective of more open markets although considering public service requirements

  10. Deep Ground Penetrating Radar (GPR) WIPL-D Models of Buried Sub-Surface Radiators

    National Research Council Canada - National Science Library

    Norgard, John D; Wicks, Michael C; Musselman, Randy L

    2005-01-01

    .... A new Ground Penetrating Radar (GPR) concept is proposed in this paper to use subsurface radiators, delivered as earth penetrating non-explosive, electronic e-bombs, as the source of strong radiated transmissions for GPR experiments...

  11. GPR142 Controls Tryptophan-Induced Insulin and Incretin Hormone Secretion to Improve Glucose Metabolism.

    Directory of Open Access Journals (Sweden)

    Hua V Lin

    Full Text Available GPR142, a putative amino acid receptor, is expressed in pancreatic islets and the gastrointestinal tract, but the ligand affinity and physiological role of this receptor remain obscure. In this study, we show that in addition to L-Tryptophan, GPR142 signaling is also activated by L-Phenylalanine but not by other naturally occurring amino acids. Furthermore, we show that Tryptophan and a synthetic GPR142 agonist increase insulin and incretin hormones and improve glucose disposal in mice in a GPR142-dependent manner. In contrast, Phenylalanine improves in vivo glucose disposal independently of GPR142. Noteworthy, refeeding-induced elevations in insulin and glucose-dependent insulinotropic polypeptide are blunted in Gpr142 null mice. In conclusion, these findings demonstrate GPR142 is a Tryptophan receptor critically required for insulin and incretin hormone regulation and suggest GPR142 agonists may be effective therapies that leverage amino acid sensing pathways for the treatment of type 2 diabetes.

  12. The pipes of pan.

    Science.gov (United States)

    Chalif, David J

    2004-12-01

    The pipes of pan is the crowning achievement of Pablo Picasso's neoclassical period of the 1920s. This monumental canvas depicts a mythological Mediterranean scene in which two sculpted classical giants stare out, seemingly across the centuries, toward a distant and lost Arcadia. Picasso was influenced by Greco-Roman art during his travels in Italy, and his neoclassical works typically portray massive, immobile, and pensive figures. Pan and his pipes are taken directly from Greek mythological lore by Picasso and placed directly into 20th century art. He frequently turned to various mythological figures throughout his metamorphosing periods. The Pipes of Pan was also influenced by the painter's infatuation with the beautiful American expatriate Sara Murphy, and the finished masterpiece represents a revision of a previously conceived neoclassical work. The Pipes of Pan now hangs in the Musee Picasso in Paris.

  13. Heat Pipe Systems

    Science.gov (United States)

    1993-01-01

    The heat pipe was developed to alternately cool and heat without using energy or any moving parts. It enables non-rotating spacecraft to maintain a constant temperature when the surface exposed to the Sun is excessively hot and the non Sun-facing side is very cold. Several organizations, such as Tropic-Kool Engineering Corporation, joined NASA in a subsequent program to refine and commercialize the technology. Heat pipes have been installed in fast food restaurants in areas where humid conditions cause materials to deteriorate quickly. Moisture removal was increased by 30 percent in a Clearwater, FL Burger King after heat pipes were installed. Relative humidity and power consumption were also reduced significantly. Similar results were recorded by Taco Bell, which now specifies heat pipe systems in new restaurants in the Southeast.

  14. Stuck pipe prediction

    KAUST Repository

    Alzahrani, Majed

    2016-03-10

    Disclosed are various embodiments for a prediction application to predict a stuck pipe. A linear regression model is generated from hook load readings at corresponding bit depths. A current hook load reading at a current bit depth is compared with a normal hook load reading from the linear regression model. A current hook load greater than a normal hook load for a given bit depth indicates the likelihood of a stuck pipe.

  15. Impact response analysis of a coaxial double-pipe structure

    International Nuclear Information System (INIS)

    Nishida, Akemi; Iigaki, Kazuhiko

    2010-01-01

    A coaxial double-pipe structure is to be used in the main primary coolant system of a high-temperature gas-cooled reactor. In order to study the vibration characteristics of a coaxial double-pipe structure, hammering tests were performed on test models of a coaxial double-pipe structure. Because high frequency components were included in the structural responses of this type of tests, impact response analysis was performed by using spectral element that has high precision in the high frequency domain. By the comparison between analysis results and experiment results, it was confirmed that the analytical results had good agreement with the experimental results. Also we performed parametric studies about damping properties of the test models. As a result of having identified the damping properties using experiment results, it was found that inner pipe and outer pipe had different damping properties. In this paper, these results were shown. (author)

  16. Leak test of the pipe line for radioactive liquid waste

    International Nuclear Information System (INIS)

    Machida, Chuji; Mori, Shoji.

    1976-01-01

    In the Tokai Research Establishment, most of the radioactive liquid waste is transferred to a wastes treatment facility through pipe lines. As part of the pipe lines a cast iron pipe for town gas is used. Leak test has been performed on all joints of the lines. For the joints buried underground, the test was made by radioactivity measurement of the soil; and for the joints in drainage ditch by the pressure and bubble methods. There were no leakage at all, indicating integrity of all the joints. On the other hand, it is also known by the other test that the corrosion of inner surface of the piping due to liquid waste is only slight. The pipe lines for transferring radioactive liquid waste are thus still usable. (auth.)

  17. Improving GPR image resolution in lossy ground using dispersive migration

    Science.gov (United States)

    Oden, C.P.; Powers, M.H.; Wright, D.L.; Olhoeft, G.R.

    2007-01-01

    As a compact wave packet travels through a dispersive medium, it becomes dilated and distorted. As a result, ground-penetrating radar (GPR) surveys over conductive and/or lossy soils often result in poor image resolution. A dispersive migration method is presented that combines an inverse dispersion filter with frequency-domain migration. The method requires a fully characterized GPR system including the antenna response, which is a function of the local soil properties for ground-coupled antennas. The GPR system response spectrum is used to stabilize the inverse dispersion filter. Dispersive migration restores attenuated spectral components when the signal-to-noise ratio is adequate. Applying the algorithm to simulated data shows that the improved spatial resolution is significant when data are acquired with a GPR system having 120 dB or more of dynamic range, and when the medium has a loss tangent of 0.3 or more. Results also show that dispersive migration provides no significant advantage over conventional migration when the loss tangent is less than 0.3, or when using a GPR system with a small dynamic range. ?? 2007 IEEE.

  18. Preliminary evaluation of GPR for nickel laterite exploration

    Science.gov (United States)

    Francke, Jan C.; Nobes, David C.

    2000-04-01

    With the dramatic growth of interest in nickel laterite resource exploration, fuelled by increased demand and new processing technologies, the need for accurate resource delineation and careful mine planning becomes paramount. The traditional use of borehole grids to calculate ore reserves is neither sufficiently accurate nor cost-effective at many sites due to the complexity of tropical weathering profiles. Although an unconventional approach to laterite mine planning and resource delineation, ground penetrating radar (GPR) has shown tremendous potential for addressing project geology, resource delineation, and mine planning issues. GPR processing techniques have been developed specifically for laterite applications and utilized successfully at a number of sites worldwide. Each site exhibits unique geology, and thus radar characteristics. The GPR data have shown excellent correlation with the weathering profile as confirmed by boreholes and test pits. GPR has significantly increased the database of knowledge regarding project geology, as well as provided invaluable assistance to mine planning by imaging the bedrock weathering texture, including the precise location of subsurface pinnacle structures and fault planes. The information provided by the GPR data, in concert with strategically placed boreholes based on these data, has enabled a laterite project to be upgraded to the measured category of mineral resource.

  19. The SCFA receptor GPR43 and energy metabolism

    Directory of Open Access Journals (Sweden)

    Ikuo eKimura

    2014-06-01

    Full Text Available Free fatty acids (FFAs are essential nutrients and act as signaling molecules in various cellular processes via binding with FFA receptors. Of these receptors, GPR43 is activated by short chain fatty acids (SCFAs; e.g., acetate, propionate, and butyrate. During feeding, SCFAs are produced by microbial fermentation of dietary fiber in the gut, and these SCFAs become important energy sources for the host. The gut microbiota affects nutrient acquisition and energy regulation of the host and can influence the development of obesity, insulin resistance, and diabetes. Recently, GPR43 has been reported to regulate host energy homeostasis in the gastrointestinal tract and adipose tissues. Hence, GPR43 is also thought to be a potential drug target for metabolic disorders, such as obesity and diabetes. In this review, we summarize the identification, structure, and activities of GPR43, with a focus on host energy regulation, and present an essential overview of our current understanding of its physiological roles in host energy regulation that is mediated by gut microbiota. We also discuss the potential for GPR43 as a therapeutic target.

  20. TOMOGRAPHIC SITE CHARACTERIZATION USING CPT, ERT, AND GPR

    Energy Technology Data Exchange (ETDEWEB)

    Rexford M. Morey; Susanne M. Conklin; Stephen P. Farrington, P.E.; James D. Shinn II, P.E.

    1999-07-01

    The US Department of Energy (DOE) is responsible for the cleanup of inactive DOE sites and for bringing DOE sites and facilities into compliance with federal, state, and local laws and regulations. The DOE's Office of Environmental Management (EM) needs advanced technologies that can make environmental restoration and waste management operations more efficient and less costly. These techniques are required to better characterize the physical, hydrogeological, and chemical properties of the subsurface while minimizing and optimizing the use of boreholes and monitoring wells. Today the cone penetrometer technique (CPT) is demonstrating the value of a minimally invasive deployment system for site characterization. Applied Research Associates, Inc. is developing two new sensor packages for site characterization and monitoring. The two new methods are: (1) Electrical Resistivity Tomography (ERT); and (2) Ground Penetrating Radar (GPR) Tomography. These sensor systems are now integrated with the CPT. The results of this program now make it possible to install ERT and GPR units by CPT methods and thereby reduce installation costs and total costs for ERT and GPR surveys. These two techniques can complement each other in regions of low resistivity where ERT is more effective and regions of high resistivity where GPR is more effective. The results show that CPT-installed GeoWells can be used for both ERT and GPR borehole tomographic subsurface imaging. These two imaging techniques can be used for environmental site characterization and monitoring have numerous and diverse applications within site cleanup and waste management operations.

  1. Modeling of GPR Clutter Caused by Soil Heterogeneity

    Directory of Open Access Journals (Sweden)

    Kazunori Takahashi

    2012-01-01

    Full Text Available In small-scale measurements, ground-penetrating radar (GPR often uses a higher frequency to detect a small object or structural changes in the ground. GPR becomes more sensitive to the natural heterogeneity of the soil when a higher frequency is used. Soil heterogeneity scatters electromagnetic waves, and the scattered waves are in part observed as unwanted reflections that are often referred to as clutter. Data containing a great amount of clutter are difficult to analyze and interpret because clutter disturbs reflections from objects of interest. Therefore, modeling GPR clutter is useful to assess the effectiveness of GPR measurements. In this paper, the development of such a technique is discussed. This modeling technique requires the permittivity distribution of soil (or its geostatistical properties and gives a nominal value of clutter power. The paper demonstrates the technique with the comparison to the data from a GPR time-lapse measurement. The proposed technique is discussed in regard to its applicability and limitations based on the results.

  2. Gas compressor with side branch absorber for pulsation control

    Science.gov (United States)

    Harris, Ralph E [San Antonio, TX; Scrivner, Christine M [San Antonio, TX; Broerman, III, Eugene L.

    2011-05-24

    A method and system for reducing pulsation in lateral piping associated with a gas compressor system. A tunable side branch absorber (TSBA) is installed on the lateral piping. A pulsation sensor is placed in the lateral piping, to measure pulsation within the piping. The sensor output signals are delivered to a controller, which controls actuators that change the acoustic dimensions of the SBA.

  3. Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91

    Directory of Open Access Journals (Sweden)

    Mette Trauelsen

    2017-12-01

    Conclusions: These novel, synthetic non-metabolite GPR91 agonists will be valuable both as pharmacological tools to delineate the GPR91-mediated functions of succinate and as leads for the development of GPR91-targeted drugs to potentially treat low grade metabolic inflammation and diabetic complications such as retinopathy and nephropathy.

  4. Cowdung gas

    Energy Technology Data Exchange (ETDEWEB)

    A basic guide for the design and construction of a small biogas plant is presented. The gas holder consists of a battery of seven used oil drums bound together with interconnected via plastic piping. Most other components, with the exception of metal valves and joints, are made of wood, stone or cement.

  5. Characteristics of gas-liquid two-phase flow in rotating pipe. 2nd Report. Pressure characteristics in downstream of the entrance of rotating pipe; Kaiten enkannai kieki nisoryu no ryudo tokusei ni kansuru kenkyu. 2. Kaitenkan iriguchi karyuiki ni okeru atsuryoku tokusei

    Energy Technology Data Exchange (ETDEWEB)

    Yamaguchi, H.; Osaka, Y. [Doshisha University, Kyoto (Japan). Faculty of Engineering

    1997-04-25

    In the present study, we report experimental results obtained from air-water two-phase flows in the downstream region of a rotating pipe which consists of three independent rotating parts with a total length of 3 m. The pressure drop characteristics associated with the change in flow behavior due to effect of the pipe rotation are examined. Particular attention is paid to the length of the rotating pipe on the pressure drop characteristics. From the results of experiment, it is revealed that the effect of the rotating pipe becomes significant in the downstream of the entrance. A correlation based on the consideration of bubble fusion number applied to the bubble fusion model (proposed in the previous report) can be used to estimate the friction multiplication factor {phi}L{sup 2} satisfactory in bubble flow and plug flow regimes for the developed rotating two-phase flows. 9 refs., 6 figs.

  6. GPR119 - a major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Co-acting in Synergy with FFA1 (GPR40)

    DEFF Research Database (Denmark)

    Ekberg, Jeppe H; Pedersen, Maria Hauge; Kristensen, Line V

    2016-01-01

    Triglycerides are among the most efficacious stimulators of incretin secretion; however the relative importance of FFA1 (GPR40), FFA4 (GPR120) and GPR119 which all recognize triglyceride metabolites, i.e. LCFA and 2-MAG respectively, is still unclear. Here, we find all three receptors to be highly...... expressed and highly enriched in FACS-purified GLP-1 and GIP cells isolated from transgenic reporter mice. In vivo, the triglyceride-induced increase in plasma GIP was significantly reduced in FFA1 deficient mice (to 34% - mean of four experiments each with 8-10 animals), in GPR119 deficient mice (to 24...... %) and in FFA1/FFA4 double deficient mice (to 15%) but not in FFA4 deficient mice. The triglyceride-induced increase in plasma GLP-1 was only significantly reduced in the GPR119 deficient and the FFA1/FFA4 double deficient mice, but not in the FFA1 and FFA4 deficient mice. In mouse colonic crypt cultures...

  7. GPR91: expanding the frontiers of Krebs cycle intermediates.

    Science.gov (United States)

    de Castro Fonseca, Matheus; Aguiar, Carla J; da Rocha Franco, Joao Antônio; Gingold, Rafael N; Leite, M Fatima

    2016-01-12

    Since it was discovered, the citric acid cycle has been known to be central to cell metabolism and energy homeostasis. Mainly found in the mitochondrial matrix, some of the intermediates of the Krebs cycle are also present in the blood stream. Currently, there are several reports that indicate functional roles for Krebs intermediates out of its cycle. Succinate, for instance, acts as an extracellular ligand by binding to a G-protein coupled receptor, known as GPR91, expressed in kidney, liver, heart, retinal cells and possibly many other tissues, leading to a wide array of physiological and pathological effects. Through GPR91, succinate is involved in functions such as regulation of blood pressure, inhibition of lipolysis in white adipose tissue, development of retinal vascularization, cardiac hypertrophy and activation of stellate hepatic cells by ischemic hepatocytes. Along the current review, these new effects of succinate through GPR91 will be explored and discussed.

  8. GPR data processing computer software for the PC

    Science.gov (United States)

    Lucius, Jeffrey E.; Powers, Michael H.

    2002-01-01

    The computer software described in this report is designed for processing ground penetrating radar (GPR) data on Intel-compatible personal computers running the MS-DOS operating system or MS Windows 3.x/95/98/ME/2000. The earliest versions of these programs were written starting in 1990. At that time, commercially available GPR software did not meet the processing and display requirements of the USGS. Over the years, the programs were refined and new features and programs were added. The collection of computer programs presented here can perform all basic processing of GPR data, including velocity analysis and generation of CMP stacked sections and data volumes, as well as create publication quality data images.

  9. A high precision buried pipe locator

    Science.gov (United States)

    Sakairi, N.; Yamada, H.; Miyamoto, Y.; Mori, K.

    1988-08-01

    A gas pipe locator based on an ac magnetic field is described. The accuracy of the depth measurement is improved with this locator. The indication of reliability which informs the operator of the degree of the error caused in the measurement is introduced in this equipment. Field test results reveal that the accuracy is enough for practical use. The reliability index is confirmed to be consistent for the calculation procedure and to be a good index for error estimation.

  10. Special Features of Structure Formation in Pipes from Medium-Carbon Low-Alloy Steel 32G2F Under Heat Treatment

    Science.gov (United States)

    Stepanov, A. I.; Belikov, S. V.; Musikhin, S. A.; Burmasov, S. P.; Popov, A. A.

    2017-03-01

    Special features of formation of structure and properties of seamless pipes from medium-carbon low-alloy steel for oil and gas applications are considered and associated with chemical inhomogeneity of the metal of the pipes.

  11. GPR and GPS data integration: examples of application in Antarctica

    Directory of Open Access Journals (Sweden)

    S. Gandolfi

    2001-06-01

    Full Text Available Ground Penetrating Radar (GPR and Global Positioning System (GPS techniques were employed in snow accumulation studies during the Italian leg of the International Trans-Antarctic Scientific Expedition (ITASE. The acquired data were useful both for glaciological and climatological studies. This paper presents some results obtained by GPR and GPS data integration employed to determine accumulation/ablation processes along the profile of the traverse that show how the snow-sublayer thickness can vary quickly in just a few kilometres. Some examples of data integration employed in detection and characterisation of buried crevasses are also presented.

  12. Radiosynthesis and characterisation of a potent and selective GPR139 agonist radioligand

    DEFF Research Database (Denmark)

    Kuhne, Sebastiaan; Nøhr, Anne Cathrine; Marek, AleŠ

    2016-01-01

    Compound 1 is a selective and potent agonist of the G protein-coupled receptor GPR139 (EC50 = 39 nM). In this study, we describe the synthesis, radiolabelling and in vitro evaluation of [3H]-1 for the characterisation of GPR139 and its spatial expression in the brain using autoradiography. Two...... to discriminate [3H]-1 binding to wildtype mice brains from GPR139 knockout mice brains and total binding from non-specific binding in CHO-k1 cells stably expressing human GPR139 receptor. Based on these experiments we conclude that [3H]-1 is not a suitable radioligand for the characterisation of GPR139....

  13. Lateral Preferential Flow in Soil Pipes on Hillslopes in the Catskill Mountains, New York, USA

    Science.gov (United States)

    Harpold, A. A.; Steenhuis, T. S.; Dahlke, H. E.

    2006-12-01

    Lateral preferential flow has been shown to be a significant factor controlling the timing and volume of hillslope runoff. In addition, preferential flow, including pipeflow, can reduce the contact time of contaminants with the soil matrix and thus profoundly alter runoff chemistry. This study examines the importance of soil pipes on hydrologic response and runoff chemistry from a hillslope in the Catskill Mountains of New York State. The pipes examined are unique in location, depth, and flow characteristics from previously published studies in North America. The implications of pipeflow on hydrologic process understanding and land management in both agricultural and pristine watersheds in the Catskills are numerous. Therefore, chemical tracers and hydrometric techniques are used to determine the hydrologic response characteristics, contributing area, and nutrient transport capacity of the pipes and non-invasive geophysical methods are used to investigate the morphology of the pipes and their importance in landscape formation. This study was conducted on a hillslope in the Town Brook watershed in the Catskill Mountains. Soil pipes were initially identified by visual and auditory reconnaissance. Soil pipe locations and frequency were further defined using ground penetrating radar (GPR). Additional pipe characteristics were estimated using simple tracer studies (using dye and salt) and by measuring the size of particles ejected by the pipe. After identification, the hillslope was instrumented with equipment capable of measuring the hydrologic response of the pipe, including a weir and tipping buckets measuring pipe outflow, a network of piezometers and tensiometers, and automated rain gauge. Water quality measurements were collected using automated samplers and event-based grab samples at several locations: upslope surface water, soil moisture (using a cluster of lysimeters), rainfall, pipe outflow, and stream water at the outlet of the subcatchment. Mixing models

  14. Pipe whip and impact

    International Nuclear Information System (INIS)

    Attwood, G.J.

    1987-01-01

    Over the past few years changes in economic and safety considerations in nuclear power plants have resulted in a need to examine the problem of pipe whip in greater detail. Consequently, experimental programmes were set up in France, North America and Britain. Results from these tests combined with analytical work indicate that pipe whip followed by impact with surrounding pipework and structures may not be as serious as had been believed. Impact loads have been found to be much less (at least five times) than those predicted to the appropriate design regulations. Hence, the use of pipe whip restraints may have been overconservative. The use of fewer, better designed restraints, would result in greater accessibility of pipework, a reduced need for inspection of restraints, and a considerable financial saving. (author)

  15. Investigation on size tolerance of pore defect of girth weld pipe

    Science.gov (United States)

    Shuai, Jian; Xu, Kui

    2018-01-01

    Welding quality control is an important parameter for safe operation of oil and gas pipes, especially for high-strength steel pipes. Size control of welding defect is a bottleneck problem for current pipe construction. As a key part of construction procedure for butt-welding of pipes, pore defects in girth weld is difficult to ignore. A three-dimensional non-linear finite element numerical model is established to study applicability of size control indices based on groove shape and softening phenomenon of material in heat-affected zone of practical pipe girth weld. Taking design criteria of pipe as the basis, basic tensile, extremely tensile and extremely compressive loading conditions are determined for pipe stress analysis, and failure criteria based on flow stress is employed to perform stress analysis for pipe girth weld with pore defect. Results show that pipe girth welding stresses of pores at various radial locations are similar. Whereas, stress for pores of different sharpness varied significantly. Besides, tolerance capability of API 5L X90 grade pipe to pore defect of girth weld is lower than that of API 5L X80 grade pipe, and size control index of 3 mm related to pore defect in current standards is applicable to API 5L X80 and X90 grade girth welded pipes with radially non-sharp pore defects. PMID:29364986

  16. GPR55, a G-protein coupled receptor for lysophosphatidylinositol, plays a role in motor coordination.

    Directory of Open Access Journals (Sweden)

    Chia-Shan Wu

    Full Text Available The G-protein coupled receptor 55 (GPR55 is activated by lysophosphatidylinositols and some cannabinoids. Recent studies found prominent roles for GPR55 in neuropathic/inflammatory pain, cancer and bone physiology. However, little is known about the role of GPR55 in CNS development and function. To address this question, we performed a detailed characterization of GPR55 knockout mice using molecular, anatomical, electrophysiological, and behavioral assays. Quantitative PCR studies found that GPR55 mRNA was expressed (in order of decreasing abundance in the striatum, hippocampus, forebrain, cortex, and cerebellum. GPR55 deficiency did not affect the concentrations of endocannabinoids and related lipids or mRNA levels for several components of the endocannabinoid system in the hippocampus. Normal synaptic transmission and short-term as well as long-term synaptic plasticity were found in GPR55 knockout CA1 pyramidal neurons. Deleting GPR55 function did not affect behavioral assays assessing muscle strength, gross motor skills, sensory-motor integration, motor learning, anxiety or depressive behaviors. In addition, GPR55 null mutant mice exhibited normal contextual and auditory-cue conditioned fear learning and memory in a Pavlovian conditioned fear test. In contrast, when presented with tasks requiring more challenging motor responses, GPR55 knockout mice showed impaired movement coordination. Taken together, these results suggest that GPR55 plays a role in motor coordination, but does not strongly regulate CNS development, gross motor movement or several types of learned behavior.

  17. A Mucosal and Cutaneous Chemokine Ligand for the Lymphocyte Chemoattractant Receptor GPR15

    Directory of Open Access Journals (Sweden)

    Borja Ocón

    2017-09-01

    Full Text Available Chemoattractants control lymphocyte recruitment from the blood, contributing to the systemic organization of the immune system. The G protein-linked receptor GPR15 mediates lymphocyte homing to the large intestines and skin. Here we show that the 9 kDa CC-motif containing cationic polypeptide AP57/colon-derived sushi containing domain-2 binding factor (CSBF, encoded by C10orf99 in the human and 2610528A11Rik in the mouse, functions as a chemokine ligand for GPR15 (GPR15L. GPR15L binds GPR15 and attracts GPR15-expressing T cells including lymphocytes in colon-draining lymph nodes and Vγ3+ thymic precursors of dermal epithelial T cells. Patterns of GPR15L expression by epithelial cells in adult mice and humans suggest a homeostatic role for the chemokine in lymphocyte localization to the large intestines, as well as a role in homing to the epidermis during wound healing or inflammation. GPR15L is also significantly expressed in squamous mucosa of the oral cavity and esophagus with still poorly defined regulation. Identification of the chemotactic activity of GPR15L adds to its reported antibacterial and tumor cell growth regulatory functions and suggests the potential of targeting GPR15L–GPR15 interactions for modulation of mucosal and cutaneous inflammation.

  18. Spatiotemporal Control of GPR37 Signaling and Its Behavioral Effects by Optogenetics

    Directory of Open Access Journals (Sweden)

    Wu Zheng

    2018-03-01

    Full Text Available Despite the progress in deorphanization of G Protein-Coupled Receptors (GPCRs, ≈100 GPCRs are still classified as orphan receptors without identified endogenous ligands and with unknown physiological functions. The lack of endogenous ligands triggering GPCR signaling has hampered the study of orphan GPCR functions. Using GPR37 as an example, we provide here the first demonstration of the channelrhodopsin 2 (ChR2-GPCR approach to bypass the endogenous ligand and selectively activate the orphan GPCR signal by optogenetics. Inspired by the opto-XR approach, we designed the ChR2-GPR37 chimera, in which the corresponding parts of GPR37 replaced the intracellular portions of ChR2. We showed that optogenetic activation of ChR2/opto-GPR37 elicited specific GPR37 signaling, as evidenced by reduced cAMP level, enhanced ERK phosphorylation and increased motor activity, confirming the specificity of opto-GPR37 signaling. Besides, optogenetic activation of opto-GPR37 uncovered novel aspects of GPR37 signaling (such as IP-3 signaling and anxiety-related behavior. Optogenetic activation of opto-GPR37 permits the causal analysis of GPR37 activity in the defined cells and behavioral responses of freely moving animals. Importantly, given the evolutionarily conserved seven-helix transmembrane structures of ChR2 and orphan GPCRs, we propose that opto-GPR37 approach can be readily applied to other orphan GPCRs for their deorphanization in freely moving animals.

  19. Heat pipes and use of heat pipes in furnace exhaust

    Science.gov (United States)

    Polcyn, Adam D.

    2010-12-28

    An array of a plurality of heat pipe are mounted in spaced relationship to one another with the hot end of the heat pipes in a heated environment, e.g. the exhaust flue of a furnace, and the cold end outside the furnace. Heat conversion equipment is connected to the cold end of the heat pipes.

  20. Enhancing the resolution of gpr spectra for pavement engineering applications

    Science.gov (United States)

    Benedetto, F.; Benedetto, A.

    2012-04-01

    Ground Penetrating Radar (GPR) is a geophysical method that uses radar pulses to image the subsurface. This non-destructive method uses electromagnetic radiation and detects the reflected signals from subsurface structures. It can detect objects, changes in material, and voids and cracks. GPR has many applications in a number of fields. In the field of civil engineering one of the most advanced technologies used for road pavement monitoring is based on the deployment of advanced GPR systems. One of the most relevant causes of road pavement damage is often referable to water intrusion in structural layers. In this context, GPR has been recently proposed as a method to estimate moisture content in a porous medium without preventive calibration. Hence, the development of methods to obtain an estimate of the moisture content is a crucial research field involving economic, social and strategic aspects in road safety for a great number of public and private Agencies. In particular, a recent new approach was proposed to estimate moisture content in a porous medium basing on the theory of Rayleigh scattering, showing a shift of the frequency peak of the GPR spectrum towards lower frequencies as the moisture content increases in the soil. The weakness characterizing this approach is represented by the needs of high resolution signals, whereas GPR spectra are affected by low resolution. Hence, the rising requirement for high resolution leads to specific demands for improved prediction methods. Recently, a new technique combining the response of the conventional fast Fourier transform (FFT, well known for its high-precision receiving signal level) with that of the MUSIC (multiple signal classification) algorithm, well known for its super-resolution capacity has been proposed. This combined method has been proved to obtain a high precision level in quantifying the shift of the frequency peak of the GPR spectrum. This combined method can perform a reliable coarse estimate of

  1. Performance of buried pipe installation.

    Science.gov (United States)

    2010-05-01

    The purpose of this study is to determine the effects of geometric and mechanical parameters : characterizing the soil structure interaction developed in a buried pipe installation located under : roads/highways. The drainage pipes or culverts instal...

  2. Assessing the safety aspects for use of multilayer pipes in gas distribution of domestic installation; Avaliacao dos aspectos de seguranca para utilizacao de tubos multicamada em instalacoes de distribuicao de gas em residencias

    Energy Technology Data Exchange (ETDEWEB)

    Bratfisch, Carlos do Amaral Coutinho [Bratfisch - Engenharia em Gas, Sao Paulo, SP (Brazil); Emmeti, Sao Paulo, SP (Brazil); Collela, Ricardo [FGS Brasil Industria e Comercio Ltda., Cotia, SP (Brazil)

    2012-07-01

    The gas distribution networks average flow at the Brazilian market is low and the operating pressure is less than 2.0 kgf/cm{sup 2}. These values are lower if compared to other countries and due this, gas distribution companies, major builders and developers have started a movement to find alternatives to reduce their installation costs, and they have identified in other countries the multilayer system. Because of the great interest of the consumer market for this alternative, and since there is no standards in Brazil that could regulate it, a technical committee was established under the ABNT in order to prepare a standard draft meeting the local market particularities as well this technology requirements. Then it was initiated a quest looking for the knowledge of the 'state of the art' of this technology in various locations around the world, especially Europe, Asia and Oceania, which shows that, with few exceptions, the knowledge of this alternative is still on the beginning, and even in countries where this system is a pioneer some doubts exist with respect to their usage limit. The multilayer system materials were already used at hot and cold water networks for more than twelve years, but only after that it was made an adaptation for building installations of gas distribution networks. Due the need to search and establish safety criteria both with respect to the product as its installation shape, did the necessary motivation to perform a more detailed study of this new technology, meeting the needs of this market. The intention is to present to the consumer market a series of comparative data definitions and techniques to identify this as a modern, updated, economic, efficient and safe alternative option for gas distribution networks. (author)

  3. Impact test on a pipe

    International Nuclear Information System (INIS)

    Noronha, R.F.; Shimura, S.H.

    1995-01-01

    A carbon steel pipe was submitted to a series of progressive impact loadings on a drop table. Strain and acceleration were measured in relevant places of the pipe and recorded in time and frequency domain. The pipe withstood impact loads up to 560 G without any visual deformation being noticed. Strains 50% over the yield point strain were measured. A high level of damping coming from the supports may have attenuated the response of the pipe. (author). 4 refs., 1 fig., 1 tab

  4. Free Fatty Acid Receptor 1 (FFA1/GPR40) Agonists

    DEFF Research Database (Denmark)

    Christiansen, Elisabeth; Due-Hansen, Maria E; Urban, Christian

    2012-01-01

    FFA1 (GPR40) is a new target for treatment of type 2 diabetes. We recently identified the potent FFA1 agonist TUG-469 (5). Inspired by the structurally related TAK-875, we explored the effects of a mesylpropoxy appendage on 5. The appendage significantly lowers lipophilicity and improves metabolic...

  5. GPR application to investigate soil crack persistence in Cianjur landslide

    Science.gov (United States)

    Irawan, S.; Aly, R. R.; Syahputra, R.; Kristyanto, T. H. W.; Tempesy, A. S.

    2017-07-01

    Cianjur region, located in West Java, is one of regions in Indonesia with high intensity of rain, where medium land movement may be inevitable. The presence of joints on sandstone outcrops conducts as water access and accelerates weathering process. The survey aims to study the continuity of the soil cracks that develop in the body of slope its density. This survey used Ground Penetrating Radar method to study landslides in both favorable and unfavorable light. Ground Penetrating Radar, GPR, is the method that adopts electromagnetic wave propagation to map subsurface properties. GPR is one of the effective methods to delineate subsurface with the highest resolution in the shallow depth, even it has highly variation results corresponded to complex of geological features and clay-rich materials. The result section showed soil crack continuation into deeper part of the layer with GPR's frequency 40MHz, most of section then showed the crack occurrence is dominated in the upper 200 ns. Crack density could be affected by mineral composition and other factors. This study resulted two lines GPR data which has different altitude. Line A which is lower than Line B has loose crack density rather than B, about approximately 40%. The area was approximately affected by landslides that usually exhibited dramatic spatial and temporal variations of lithological and hydrogeological conditions. It will need further survey to know the effect of soil crack toward the sliding surface of the landslide from other surveys.

  6. The Application of GPR in Florida for Detecting Forensic Burials

    Energy Technology Data Exchange (ETDEWEB)

    S. K. Koppenjan; J. J. Schultz; S. Ono; H. Lee

    2003-01-01

    A study was performed at the University of Florida to measure ground penetrating radar(GPR) performance for detecting forensic burials. In controlled scenarios, 24 burials were constructed with pig cadavers. Two soils were utilized to represent two of the most common soil orders in Florida: an Entisol and an Ultisol. Graves were monitored on a monthly basis for time periods up to 21 months with grid data acquired with pulsed and swept-frequency GPR systems incorporating several different frequency antennas. A small subset of the graves was excavated to assess decomposition and relate to the GPR images during the test. The grave anomalies in the GPR depth profiles became less distinctive over time due to body decomposition and settling of the disturbed soil (backfill) as it compacted. Soil type was a major factor. Grave anomalies became more difficult to recognize over time for deep targets that were within clay. Forensic targets that were in sandy soil were recognized for the duration of this study. Time elapsed imagery will be presented to elucidate the changes, or lack thereof, of grave anomalies over the duration of this study. Further analysis was performed using Synthetic Aperture Radar (SAR) reconstruction of images in 2-D and 3-D.

  7. Mapping soil water content on golf course greens with GPR

    Science.gov (United States)

    Ground-penetrating radar (GPR) can be an effective and efficient method for high-resolution mapping of volumetric water content in the sand layer directly beneath the ground surface at a golf course green. This information could potentially be very useful to golf course superintendents for determi...

  8. GPR68 Senses Flow and Is Essential for Vascular Physiology.

    Science.gov (United States)

    Xu, Jie; Mathur, Jayanti; Vessières, Emilie; Hammack, Scott; Nonomura, Keiko; Favre, Julie; Grimaud, Linda; Petrus, Matt; Francisco, Allain; Li, Jingyuan; Lee, Van; Xiang, Fu-Li; Mainquist, James K; Cahalan, Stuart M; Orth, Anthony P; Walker, John R; Ma, Shang; Lukacs, Viktor; Bordone, Laura; Bandell, Michael; Laffitte, Bryan; Xu, Yan; Chien, Shu; Henrion, Daniel; Patapoutian, Ardem

    2018-04-19

    Mechanotransduction plays a crucial role in vascular biology. One example of this is the local regulation of vascular resistance via flow-mediated dilation (FMD). Impairment of this process is a hallmark of endothelial dysfunction and a precursor to a wide array of vascular diseases, such as hypertension and atherosclerosis. Yet the molecules responsible for sensing flow (shear stress) within endothelial cells remain largely unknown. We designed a 384-well screening system that applies shear stress on cultured cells. We identified a mechanosensitive cell line that exhibits shear stress-activated calcium transients, screened a focused RNAi library, and identified GPR68 as necessary and sufficient for shear stress responses. GPR68 is expressed in endothelial cells of small-diameter (resistance) arteries. Importantly, Gpr68-deficient mice display markedly impaired acute FMD and chronic flow-mediated outward remodeling in mesenteric arterioles. Therefore, GPR68 is an essential flow sensor in arteriolar endothelium and is a critical signaling component in cardiovascular pathophysiology. Copyright © 2018 Elsevier Inc. All rights reserved.

  9. Tomographic reconstruction of structures using a novel GPR system

    Science.gov (United States)

    Fedeli, Alessandro; Ježová, Jana; Lambot, Sébastien; Pastorino, Matteo; Randazzo, Andrea; Pajewski, Lara

    2017-04-01

    The ever growing range of applications of ground penetrating radar (GPR) motivates the need of developing efficient measurement systems combined with effective data processing methods. On the one hand, advanced GPR measurement systems require to accurately model the physical effects occurring between the antenna structure and the medium. On the other hand, the GPR device should provide a reliable reconstruction of the properties of the targets under an inspection to a common user. In this work, a novel GPR system was tested for the imaging of buried structures. First of all, the acquired experimental data were pre-processed with a proper calibration technique for removing antenna effects. After that, a reconstruction of a hidden structure was obtained by means of both qualitative and quantitative electromagnetic inverse scattering methods. In particular, while the qualitative techniques aim at reconstructing only specific features of the targets (e.g., location, shape), the proposed quantitative method has the challenging goal of the complete electromagnetic characterization of the buried structures. The performance of the new system was evaluated in different operating conditions with promising results. Acknowledgment This work benefited from the networking activities within the EU funded COST Action TU1208, "Civil Engineering Applications of Ground Penetrating Radar". Part of this work was carried out during the Short-Term Scientific Mission STSM-TU1208-34990 "Testing of a new lightweight radar system for tomographical reconstruction of circular structures" (Alessandro Fedeli, Italy, visiting Prof. Sébastien Lambot, Belgium).

  10. Discovery of a potent and selective GPR120 agonist

    DEFF Research Database (Denmark)

    Shimpukade, Bharat; Hudson, Brian D; Hovgaard, Christine Kiel

    2012-01-01

    GPR120 is a receptor of unsaturated long-chain fatty acids reported to mediate GLP-1 secretion, insulin sensitization, anti-inflammatory, and anti-obesity effects and is therefore emerging as a new potential target for treatment of type 2 diabetes and metabolic diseases. Further investigation is ...

  11. Application of GPR in the study of shallow subsurface sedimentary ...

    Indian Academy of Sciences (India)

    image the sedimentary structures and depositional architecture in the shallow subsurface. Correctly processed radar profiles have been used success- fully to construct the radar stratigraphy in both, ancient and modern sand bodies (Jol and Smith. 1991; Gawthorpe et al 1993). The use of GPR in sedimentology requires ...

  12. GPR Signal Denoising and Target Extraction With the CEEMD Method

    KAUST Repository

    Li, Jing

    2015-04-17

    In this letter, we apply a time and frequency analysis method based on the complete ensemble empirical mode decomposition (CEEMD) method in ground-penetrating radar (GPR) signal processing. It decomposes the GPR signal into a sum of oscillatory components, with guaranteed positive and smoothly varying instantaneous frequencies. The key idea of this method relies on averaging the modes obtained by empirical mode decomposition (EMD) applied to several realizations of Gaussian white noise added to the original signal. It can solve the mode-mixing problem in the EMD method and improve the resolution of ensemble EMD (EEMD) when the signal has a low signal-to-noise ratio. First, we analyze the difference between the basic theory of EMD, EEMD, and CEEMD. Then, we compare the time and frequency analysis with Hilbert-Huang transform to test the results of different methods. The synthetic and real GPR data demonstrate that CEEMD promises higher spectral-spatial resolution than the other two EMD methods in GPR signal denoising and target extraction. Its decomposition is complete, with a numerically negligible error.

  13. GPR Laboratory Tests For Railways Materials Dielectric Properties Assessment

    Directory of Open Access Journals (Sweden)

    Francesca De Chiara

    2014-10-01

    Full Text Available In railways Ground Penetrating Radar (GPR studies, the evaluation of materials dielectric properties is critical as they are sensitive to water content, to petrographic type of aggregates and to fouling condition of the ballast. Under the load traffic, maintenance actions and climatic effects, ballast condition change due to aggregate breakdown and to subgrade soils pumping, mainly on existing lines with no sub ballast layer. The main purpose of this study was to validate, under controlled conditions, the dielectric values of materials used in Portuguese railways, in order to improve the GPR interpretation using commercial software and consequently the management maintenance planning. Different materials were tested and a broad range of in situ conditions were simulated in laboratory, in physical models. GPR tests were performed with five antennas with frequencies between 400 and 1800 MHz. The variation of the dielectric properties was measured, and the range of values that can be obtained for different material condition was defined. Additionally, in situ GPR measurements and test pits were performed for validation of the dielectric constant of clean ballast. The results obtained are analyzed and the main conclusions are presented herein.

  14. Optimization of Pipe Networks

    DEFF Research Database (Denmark)

    Hansen, C. T.; Madsen, Kaj; Nielsen, Hans Bruun

    1991-01-01

    algorithm using successive linear programming is presented. The performance of the algorithm is illustrated by optimizing a network with 201 pipes and 172 nodes. It is concluded that the new algorithm seems to be very efficient and stable, and that it always finds a solution with a cost near the best...

  15. Flexible Heat Pipe

    Science.gov (United States)

    Bienert, W. B.; Wolf, D. A.

    1985-01-01

    Narrow Tube carries 10 watts or more to moving parts. Heat pipe 12 inches long and diameter of 0.312 inch (7.92mm). Bent to minimum radius of 2.5 blocks. Flexible section made of 321 stainless steel tubing (Cajon Flexible Tubing or equivalent). Evaporator and condenser made of oxygen free copper. Working fluid methanol.

  16. HPFRCC - Extruded Pipes

    DEFF Research Database (Denmark)

    Stang, Henrik; Pedersen, Carsten

    1996-01-01

    The present paper gives an overview of the research onHigh Performance Fiber Reinforced Cementitious Composite -- HPFRCC --pipes recently carried out at Department of Structural Engineering, Technical University of Denmark. The project combines material development, processing technique developme...... of the newly extruded material....

  17. Precast concrete unit assessment through GPR survey and FDTD modelling

    Science.gov (United States)

    Campo, Davide

    2017-04-01

    Precast concrete elements are widely used within United Kingdom house building offering ease in assembly and added values as structural integrity, sound and thermal insulation; most common concrete components include walls, beams, floors, panels, lintels, stairs, etc. The lack of respect of the manufacturer instruction during assembling, however, may induce cracking and short/long term loss of bearing capacity. GPR is a well-established not destructive technique employed in the assessment of structural elements because of real-time imaging, quickness of data collecting and ability to discriminate finest structural details. In this work, GPR has been used to investigate two different precast elements: precast reinforced concrete planks constituting the roof slab of a school and precast wood-cement blocks with insulation material pre-fitted used to build a perimeter wall of a private building. Visible cracks affected both constructions. For the assessment surveys, a GSSI 2.0 GHz GPR antenna has been used because of the high resolution required and the small size of the antenna case (155 by 90 by 105mm) enabling scanning up to 45mm from any obstruction. Finite Difference Time Domain (FDTD) numerical modelling was also performed to build a scenario of the expected GPR signal response for a preliminary real-time interpretation and to help solve uncertainties due to complex reflection patterns: simulated radargrams were built using Reflex Software v. 8.2, reproducing the same GPR pulse used for the surveys in terms of wavelet, nominal frequency, sample frequency and time window. Model geometries were derived from the design projects available both for the planks and the blocks; the electromagnetic properties of the materials (concrete, reinforcing bars, air-filled void, insulation and wooden concrete) were inferred from both values reported in literature and a preliminary interpretation of radargrams where internal layer interfaces were clearly recognizable and

  18. GPR use and activities in the Czech Republic

    Science.gov (United States)

    Stryk, Josef; Matula, Radek

    2014-05-01

    In the field of civil engineering applications in the Czech Republic, Ground Penetrating Radar (GPR) is used particularly for the diagnostics of roads and bridges. There is no producer of GPR in the Czech Republic, sets of different producers are used, particularly Geophysical Survey Systems, Inc. (USA) and MALÅ GeoScience (Sweden). The measurement results are mostly processed by software Radan, Road Doctor Pro, ReflexW and RadEx. The only technical specification in the Czech Republic is TP 233 issued by the Ministry of Transport, which describes the diagnostics of roads by GPR. Apart from a basic description of the method and a measurement system, it mentions possible applications. The only application where accuracy is mentioned is the locating of dowels and tie bars in concrete road pavements, which states that if calibration is performed, the expected depth accuracy is up to 1.0 cm. The following R&D project is currently in progress: New diagnostics methods as a supporting decision tool for maintenance and repair of road pavements - their contribution and ways of their usage (2012-2014) The project aims to test possible non-destructive methods (particularly GPR and laser scanning), make recommendations when and how to use specific methods for individual applications and for changes in technical specifications. The following R&D projects have been recently completed: Position of dowels and tie bars in rigid pavements and importance of their correct placement to pavement performance and service life (2012-2013) The project included an analysis of individual NDT methods used for the location of dowels and tie bars and for testing of their accuracy - GPR, MIT-scan and GPR in combination with a metal detector. Multichannel ground penetrating radar as a tool for monitoring of road and bridge structures (2009-2011) The project included detection of hollow spaces under non-reinforced concrete pavements, detection of excessive amount of water in road construction

  19. Analyses and Measures of GPR Signal with Superimposed Noise

    Science.gov (United States)

    Chicarella, Simone; Ferrara, Vincenzo; D'Atanasio, Paolo; Frezza, Fabrizio; Pajewski, Lara; Pavoncello, Settimio; Prontera, Santo; Tedeschi, Nicola; Zambotti, Alessandro

    2014-05-01

    The influence of EM noises and environmental hard conditions on the GPR surveys has been examined analytically [1]. In the case of pulse radar GPR, many unwanted signals as stationary clutter, non-stationary clutter, random noise, and time jitter, influence the measurement signal. When GPR is motionless, stationary clutter is the most dominant signal component due to the reflections of static objects different from the investigated target, and to the direct antenna coupling. Moving objects like e.g. persons and vehicles, and the swaying of tree crown, produce non-stationary clutter. Device internal noise and narrowband jamming are e.g. two potential sources of random noises. Finally, trigger instabilities generate random jitter. In order to estimate the effective influence of these noise signal components, we organized some experimental setup of measurement. At first, we evaluated for the case of a GPR basic detection, simpler image processing of radargram. In the future, we foresee experimental measurements for detection of the Doppler frequency changes induced by movements of targets (like physiological movements of survivors under debris). We obtain image processing of radargram by using of GSSI SIR® 2000 GPR system together with the UWB UHF GPR-antenna (SUB-ECHO HBD 300, a model manufactured by Radarteam company). Our work includes both characterization of GPR signal without (or almost without) a superimposed noise, and the effect of jamming originated from the coexistence of a different radio signal. For characterizing GPR signal, we organized a measurement setup that includes the following instruments: mod. FSP 30 spectrum analyser by Rohde & Schwarz which operates in the frequency range 9 KHz - 30 GHz, mod. Sucoflex 104 cable by Huber Suhner (10 MHz - 18 GHz), and HL050 antenna by Rohde & Schwarz (bandwidth: from 850 MHz to 26.5 GHz). The next analysis of superimposed jamming will examine two different signal sources: by a cellular phone and by a

  20. Tomographic Site Characterization Using CPT, ERT, and GPR

    Energy Technology Data Exchange (ETDEWEB)

    Rexford M. Morey

    1997-05-23

    The U.S. Department of Energy (DOE) is responsible for the cleanup of inactive DOE sites and for bringing DOE sites and facilities into compliance with federal, state and local laws and regulations. The DOE's Office of Environmental Management (EM) needs advanced technologies that can make environmental restoration and waste management operations more efficient and less costly. These techniques are required to better characterize the physical, hydrogeological, and chemical properties of the subsurface while minimizing and optimizing the use of boreholes and monitoring wells. Today the cone penetrometer technique (CPT) is demonstrating the value of a minimally invasive deployment system fix site characterization. Applied Research Associates is developing two new sensor packages for site characterization and monitoring. The two new methods are: . Electrical Resistivity Tomography (ERT) and . Ground Penetrating Radar (GPR) Tomography. These sensor systems are now integrated with the Cone Penetrometer Technique (CPT). The results of this program now make it possible to install ERT and GPR units by CPT methods and thereby reduce installation costs and total costs for ERT and GPR surveys. These two techniques can complement each other in regions of low resistivity where ERT is more effective and regions of high resistivity where GPR is more effective. The results show that CPT-installed GeoWells can be used in both ERT and GPR borehole tomographic subsurface imaging. These two imaging techniques can be used for environmental site characterization and environmental remediation monitoring. Technologies used for site characterization and monitoring have numerous and diverse applications within site clean-up and waste management operations.

  1. Analysis of thin fractures with GPR: from theory to practice

    Science.gov (United States)

    Arosio, Diego; Zanzi, Luigi; Longoni, Laura; Papini, Monica

    2017-04-01

    Whenever we perform a GPR survey to investigate a rocky medium, being the ultimate purpose of the survey either to study the stability of a rock slope or to determine the soundness of a quarried rock block, we would like mainly to detect any fracture within the investigated medium and, possibly, to estimate the parameters of the fractures, namely thickness and filling material. In most of the practical cases, rock fracture thicknesses are very small when compared to the wavelength of the electromagnetic radiation generated by the GPR systems. In such cases, fractures are to be considered as thin beds, i.e. two interfaces whose distance is smaller than GPR resolving capability, and the reflected signal is the sum of the electromagnetic reverberation within the bed. According to this, fracture parameters are encoded in the thin bed complex response and in this work we propose a methodology based on deterministic deconvolution to process amplitude and phase information in the frequency domain to estimate fracture parameters. We first present some theoretical aspects related to thin bed response and a sensitivity analysis concerning fracture thickness and filling. Secondly, we deal with GPR datasets collected both during laboratory experiments and in the facilities of quarrying activities. In the lab tests fractures were simulated by placing materials with known electromagnetic parameters and controlled thickness in between two small marble blocks, whereas field GPR surveys were performed on bigger quarried ornamental stone blocks before they were submitted to the cutting process. We show that, with basic pre-processing and the choice of a proper deconvolving signal, results are encouraging although an ambiguity between thickness and filling estimates exists when no a-priori information is available. Results can be improved by performing CMP radar surveys that are able to provide additional information (i.e., variation of thin bed response versus offset) at the expense

  2. Uniaxial Fatigue of HDPE-100 Pipe. Experimental Analysis

    Directory of Open Access Journals (Sweden)

    A. Aid

    2014-04-01

    Full Text Available In this paper, an experimental analysis for determining the fatigue strength of PE-100, one of the most used High Density Polyethylene (HDPE materials for pipes, under cyclic axial loadings is presented. HDPE is a thermoplastic material used for piping systems, such as natural gas distribution systems, sewer systems and cold water systems, which provides a good alternative to metals such as cast iron or carbon steel. One of the causes for failures of HDPE pipes is fatigue which is the result of pipes being subjected to cyclic loading, such as internal pressure, weight loads or external loadings on buried pipes, which generate stress in different directions: circumferential, longitudinal and radial. HDPE pipes are fabricated using an extrusion process, which generates anisotropic properties. By testing in the Laboratory a series of identical specimens obtained directly from PE-100 HDPE pipes in longitudinal directions, the relationships between amplitude stress and number of cycles (S-N curve test frequency 2 Hz and stress ratio R = 0.0 are established.

  3. GPR expression in the rat taste bud relating to fatty acid sensing.

    Science.gov (United States)

    Matsumura, Shigenobu; Mizushige, Takafumi; Yoneda, Takeshi; Iwanaga, Toshihiko; Tsuzuki, Satoshi; Inoue, Kazuo; Fushiki, Tohru

    2007-02-01

    We investigated the expression of G protein-coupled receptor GPR40 and GPR120 in the rat tongue. Using reverse transcription polymerase chain reaction, we detected a significant expression of GPR120 mRNA in the epithelium of the circumvallate papillae but not in the nonsensory epithelium, while the expression of GPR40 mRNA was undetectable in the sensory papillae. Western blotting analysis of colon and circumvallate papillae for GPR120 showed a protein band with a molecular weight that corresponds to that of GPR120, indicating that this antibody could recognize a native form of GPR120. Immunohistochemistry using anti-GPR120 antibody revealed GPR120 immunoreactivity in the enteroendocrine cells of the colon. Furthermore, some cells in each taste bud were stained positively with more intense labeling in the apical part of the cells. These results suggested that GPR120 is expressed in the taste cells of the circumvallate papillae to sense dietary fat, like the receptor expressed in the enteroendocrine cells.

  4. The role of the obestatin/GPR39 system in human gastric adenocarcinomas.

    Science.gov (United States)

    Alén, Begoña O; Leal-López, Saúl; Alén, María Otero; Viaño, Patricia; García-Castro, Victoria; Mosteiro, Carlos S; Beiras, Andrés; Casanueva, Felipe F; Gallego, Rosalía; García-Caballero, Tomás; Camiña, Jesús P; Pazos, Yolanda

    2016-02-02

    Obestatin, a 23-amino acid peptide encoded by the ghrelin gene, and the GPR39 receptor were reported to be involved in the control of mitogenesis of gastric cancer cell lines; however, the relationship between the obestatin/GPR39 system and gastric cancer progression remains unknown. In the present study, we determined the expression levels of the obestatin/GPR39 system in human gastric adenocarcinomas and explored their potential functional roles. Twenty-eight patients with gastric adenocarcinomas were retrospectively studied, and clinical data were obtained. The role of obestatin/GPR39 in gastric cancer progression was studied in vitro using the human gastric adenocarcinoma AGS cell line. Obestatin exogenous administration in these GPR39-bearing cells deregulated the expression of several hallmarks of the epithelial-mesenchymal transition (EMT) and angiogenesis. Moreover, obestatin signaling promoted phenotypic changes via GPR39, increasingly impacting on the cell morphology, proliferation, migration and invasion of these cells. In healthy human stomachs, obestatin expression was observed in the neuroendocrine cells and GPR39 expression was localized mainly in the chief cells of the oxyntic glands. In human gastric adenocarcinomas, no obestatin expression was found; however, an aberrant pattern of GPR39 expression was discovered, correlating to the dedifferentiation of the tumor. Altogether, our data strongly suggest the involvement of the obestatin/GPR39 system in the pathogenesis and/or clinical outcome of human gastric adenocarcinomas and highlight the potential usefulness of GPR39 as a prognostic marker in gastric cancer.

  5. Heat pipe applications workshop report

    International Nuclear Information System (INIS)

    Ranken, W.A.

    1978-04-01

    The proceedings of the Heat Pipe Applications Workshop, held at the Los Alamos Scientific Laboratory October 20-21, 1977, are reported. This workshop, which brought together representatives of the Department of Energy and of a dozen industrial organizations actively engaged in the development and marketing of heat pipe equipment, was convened for the purpose of defining ways of accelerating the development and application of heat pipe technology. Recommendations from the three study groups formed by the participants are presented. These deal with such subjects as: (1) the problem encountered in obtaining support for the development of broadly applicable technologies, (2) the need for applications studies, (3) the establishment of a heat pipe technology center of excellence, (4) the role the Department of Energy might take with regard to heat pipe development and application, and (5) coordination of heat pipe industry efforts to raise the general level of understanding and acceptance of heat pipe solutions to heat control and transfer problems

  6. Automatic inspection of oil and gas pipe welded joints by radiographic images analyses; Analise automatica de imagens radiologicas aplicada a inspecao de juntas soldadas em tubulacoes de oleo e gas

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, Guilherme A.; Felisberto, Marcelo K.; Pilkel, Lucas V.; Centeno, Tania M.; Arruda, Lucia V.R. [Centro Federal de Educacao Tecnologica do Parana (CEFET-PR), Curitiba, PR (Brazil). Curso de Pos-graduacao em Engenharia Eletrica e Informatica (CPGEI). Lab. de Automacao e Sistemas de Controle Avancado

    2004-07-01

    The reliability and integrity evaluation of structures and equipment on the petroleum and gas industry is an absolute necessary care due to economic reasons and safety. As a consequence, new supporting technologies for well known nondestructive test and evaluation methods have been developed in order to automate these inspection processes, improving their robustness, accuracy and quickness. On this way, the present work introduces solutions to overcome some obstacles to the automation of the radiographic image analysis task for the pipeline weld joint inspection, on radiographic non-destructive tests and evaluations. The main contributions are related to the improvements to techniques for the automatic weld bean segmentation and the development of an effective algorithm for the weld bean defect detection and extraction of relevant defect descriptors. (author)

  7. Reliability-based assessment of polyethylene pipe creep lifetime

    Energy Technology Data Exchange (ETDEWEB)

    Khelif, Rabia [LaMI-UBP and IFMA, Campus de Clermont-Fd, Les Cezeaux, BP 265, 63175 Aubiere Cedex (France); LR3MI, Departement de Genie Mecanique, Universite Badji Mokhtar, BP 12, Annaba 23000 (Algeria)], E-mail: rabia.khelif@ifma.fr; Chateauneuf, Alaa [LGC-University Blaise Pascal, Campus des Cezeaux, BP 206, 63174 Aubiere Cedex (France)], E-mail: alaa.chateauneuf@polytech.univ-bpclermont.fr; Chaoui, Kamel [LR3MI, Departement de Genie Mecanique, Universite Badji Mokhtar, BP 12, Annaba 23000 (Algeria)], E-mail: chaoui@univ-annaba.org

    2007-12-15

    Lifetime management of underground pipelines is mandatory for safe hydrocarbon transmission and distribution systems. The use of high-density polyethylene tubes subjected to internal pressure, external loading and environmental variations requires a reliability study in order to define the service limits and the optimal operating conditions. In service, the time-dependent phenomena, especially creep, take place during the pipe lifetime, leading to significant strength reduction. In this work, the reliability-based assessment of pipe lifetime models is carried out, in order to propose a probabilistic methodology for lifetime model selection and to determine the pipe safety levels as well as the most important parameters for pipeline reliability. This study is enhanced by parametric analysis on pipe configuration, gas pressure and operating temperature.

  8. Reliability-based assessment of polyethylene pipe creep lifetime

    International Nuclear Information System (INIS)

    Khelif, Rabia; Chateauneuf, Alaa; Chaoui, Kamel

    2007-01-01

    Lifetime management of underground pipelines is mandatory for safe hydrocarbon transmission and distribution systems. The use of high-density polyethylene tubes subjected to internal pressure, external loading and environmental variations requires a reliability study in order to define the service limits and the optimal operating conditions. In service, the time-dependent phenomena, especially creep, take place during the pipe lifetime, leading to significant strength reduction. In this work, the reliability-based assessment of pipe lifetime models is carried out, in order to propose a probabilistic methodology for lifetime model selection and to determine the pipe safety levels as well as the most important parameters for pipeline reliability. This study is enhanced by parametric analysis on pipe configuration, gas pressure and operating temperature

  9. Life cycle guideline of petrochemical plant underground piping system

    Directory of Open Access Journals (Sweden)

    Shih Jeng-Ywan

    2017-01-01

    Full Text Available According to statistics of petrochemical plant disaster, the type of underground pipeline leakage is the highest proportion, for example, Kaohsiung gas explosion in 2014 is a typical case. Therefore, improvement strategy of petrochemical plant underground piping system from both engineering and management becomes an important issue. Through reviewing regulations as well as surveying questionnaire, including kinds of piping materials, 3D drawing files, operation procedures, information sharing, etc., the findings show lack contact of integrated management with engineering executive and insufficient technical requirements are major defects. Overviewing current problems of domestic petrochemical plant underground piping system management, and comparing to international criteria and specifications, this research focuses on the of piping design, construction, operations, maintenance, and inspection. Then management procedures and engineering technical feasibility strategies are suggested. In addition, the proposed life cycle guideline in order to reduce the disaster incidence of petrochemical plant underground pipelines.

  10. Nuclear piping and pipe support design and operability relating to loadings and small bore piping

    International Nuclear Information System (INIS)

    Stout, D.H.; Tubbs, J.M.; Callaway, W.O.; Tang, H.T.; Van Duyne, D.A.

    1994-01-01

    The present nuclear piping system design practices for loadings, multiple support design and small bore piping evaluation are overly conservative. The paper discusses the results developed for realistic definitions of loadings and loading combinations with methodology for combining loads under various conditions for supports and multiple support design. The paper also discusses a simplified method developed for performing deadweight and thermal evaluations of small bore piping systems. Although the simplified method is oriented towards the qualification of piping in older plants, this approach is applicable to plants designed to any edition of the ASME Section III or B31.1 piping codes

  11. 1956 : the year of the pipe

    International Nuclear Information System (INIS)

    Anon.

    2008-01-01

    In 1956, Westcoast Transmission Company Limited announced that it would build a 650-mile export pipeline through British Columbia. However, the project faced several delays due to extremely high costs. It was the efforts of Trans-Canada Pipe Lines Limited to recruit supply contracts that laid the foundation for the system that would eventually deliver nearly 800 million cubic feet of gas per day to consumers in eastern Canada and the United States. Trans-Canada's favoured plan was to build east to Winnipeg, then south into the United States, allowing western Canadian gas to serve U.S. markets, while gas imported from the U.S. would serve markets in eastern Canada. However, the federal transport minister insisted on an all-Canadian route which forced Trans-Canada to build across the Canadian Shield, significantly increasing construction costs. Since American investors did not want any part of the new plan, a compromise was reached whereby Trans-Canada would build the Alberta-Winnipeg segment with financial aid from the federal government. The segment east from Winnipeg would also be financed from the federal government to serve markets in Ontario and Montreal, but the section would be leased back to Trans-Canada. Other key events in 1956 included construction of the gathering system by Alberta Gas Trunk Line Limited; plans for Interprovincial Pipe Line Limited to build an extension from Sarnia to Toronto; and, the beginning of development drilling by Imperial Oil at Norman Wells. 1 tab., 1 fig

  12. GPR Activities in Italy: a Review

    Science.gov (United States)

    Tosti, Fabio; Ambrosanio, Michele; Battaglia, Enzo; Bianchini Ciampoli, Luca; De Carlo, Lorenzo; Matera, Loredana; Prontera, Santo; Sileo, Maria

    2015-04-01

    the ASTM D 4748-98 and the ASTM D 6432-99 dealing with, respectively, thicknesses evaluation of bound layers in road pavements, and equipment, field procedures and data-interpretation for the electromagnetic evaluation of subsurface materials, it has to be noted that the Italian body of laws and rules tackles the ground-penetrating radar applications under an indirect and partial approach. Despite of such situation, national guidelines concerning utilities-detection activities as well as other theoretical and practical guidelines established by the major Italian private enterprises on this field can be also considered highly relevant. Moreover, a further focus on the activities and main devices of the major Italian ground-penetrating radar manufacturers have been thoroughly described. Under a research and innovation perspective, the most important test sites, such as the site of the University of Salento to reconstruct archaeological and urban subsurface scenarios have been listed along with the main advances reached in integrating ground-penetrating radar with other non-destructive techniques, to inform and potentially improve the possibility of new developments and collaborations. Acknowledgements - This work is a contribution from the Training School on "Civil Engineering Applications of GPR" held in Pisa, Italy, on September 22nd - 25th, 2014, within the framework of the COST Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar".

  13. 77 FR 17119 - Pipeline Safety: Cast Iron Pipe (Supplementary Advisory Bulletin)

    Science.gov (United States)

    2012-03-23

    ... Pipeline and Hazardous Materials Safety Administration Pipeline Safety: Cast Iron Pipe (Supplementary...; October 11, 1991 and ALN-92-02; June 26, 1992) covering the continued use of cast iron pipe in natural gas... toward finding the cause. On February 9, 2011, five people lost their lives and a number of homes were...

  14. Whistling of pipes with narrow corrugations: scale model tests and consequences for carcass design

    NARCIS (Netherlands)

    Golliard, J.; Belfroid, S.P.C.; Bendiksen, E.; Frimodt, C.

    2013-01-01

    Pipes for gas production and transport with a corrugated inner surface, as used in flexible pipes, can be subject to Flow-Induced Pulsations when the flow velocity is larger than a certain velocity. This onset velocity is dependent on the geometry of the corrugations, the operational conditions and

  15. Influence of physical aging on impact embrittlement of uPVC pipes

    NARCIS (Netherlands)

    Visser, Roy; Bor, Teunis Cornelis; Wolters, Mannes; Warnet, Laurent; Govaert, L.E.

    2011-01-01

    Most failures of unplasticised poly(vinyl chloride) (uPVC) pipes used in the Dutch gas distribution network originate from third party damage. Brittle pipes should therefore be replaced to ensure safe operation of the network. In this study, the relation between physical aging and embrittlement of

  16. The effect of external boundary conditions on condensation heat transfer in rotating heat pipes

    Science.gov (United States)

    Daniels, T. C.; Williams, R. J.

    1979-01-01

    Experimental evidence shows the importance of external boundary conditions on the overall performance of a rotating heat pipe condenser. Data are presented for the boundary conditions of constant heat flux and constant wall temperature for rotating heat pipes containing either pure vapor or a mixture of vapor and noncondensable gas as working fluid.

  17. 49 CFR 192.113 - Longitudinal joint factor (E) for steel pipe.

    Science.gov (United States)

    2010-10-01

    ... SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Pipe Design... design formula in § 192.105 is determined in accordance with the following table: Specification Pipe... Electric-fusion-welded 1.00 ASTM A 691 Electric-fusion-welded 1.00 API 5 L Seamless 1.00 Electric...

  18. Drill pipe protector development

    Energy Technology Data Exchange (ETDEWEB)

    Thomerson, C.; Kenne, R. [Regal International Corp., Corsicanna, TX (United States); Wemple, R.P. [Sandia National Lab., Albuquerque, NM (United States)] [ed.] [and others

    1996-03-01

    The Geothermal Drilling Organization (GDO), formed in the early 1980s by the geothermal industry and the U.S. Department of Energy (DOE) Geothermal Division, sponsors specific development projects to advance the technologies used in geothermal exploration, drilling, and production phases. Individual GDO member companies can choose to participate in specific projects that are most beneficial to their industry segment. Sandia National Laboratories is the technical interface and contracting office for the DOE in these projects. Typical projects sponsored in the past have included a high temperature borehole televiewer, drill bits, muds/polymers, rotary head seals, and this project for drill pipe protectors. This report documents the development work of Regal International for high temperature geothermal pipe protectors.

  19. LHCb: Beam Pipe portrait

    CERN Multimedia

    LHCb, Collaboration

    2005-01-01

    The proton beams circulate in the accelerator in Ultra High Vacuum to make them interact only with each other when colliding at the interaction point. A special beam pipe "holds" the vacuum where they pass through the LHCb detector: it has to be mechanically very strong to stand the difference in pressure between the vacuum inside it and the air in the cavern but also be as transparent as possible for the particles originating in the proton−proton collisions.

  20. LHCb: Beam Pipe

    CERN Multimedia

    LHCb, Collaboration

    2005-01-01

    The proton beams circulate in the accelerator in Ultra High Vacuum to make them interact only with each other when colliding at the interaction point. A special beam pipe "holds" the vacuum where they pass through the LHCb detector:it has to be mechanically very strong to stand the difference in pressure between the vacuum inside it and the air in the cavern but also be as transparent as possible for the particles originating in the proton−proton collisions.

  1. Pipe clamp effects on thin-walled pipe design

    International Nuclear Information System (INIS)

    Lindquist, M.R.

    1980-01-01

    Clamp induced stresses in FFTF piping are sufficiently large to require structural assessment. The basic principles and procedures used in analyzing FFTF piping at clamp support locations for compliance with ASME Code rules are given. Typical results from a three-dimensional shell finite element pipe model with clamp loads applied over the clamp/pipe contact area are shown. Analyses performed to categorize clamp induced piping loads as primary or secondary in nature are described. The ELCLAMP Computer Code, which performs analyses at clamp locations combining clamp induced stresses with stresses from overall piping system loads, is discussed. Grouping and enveloping methods to reduce the number of individual clamp locations requiring analysis are described

  2. Essential Regulation of Lung Surfactant Homeostasis by the Orphan G Protein-Coupled Receptor GPR116

    Directory of Open Access Journals (Sweden)

    Mi Young Yang

    2013-05-01

    Full Text Available GPR116 is an orphan seven-pass transmembrane receptor whose function has been unclear. Global disruption of the Gpr116 gene in mice revealed an unexpected, critical role for this receptor in lung surfactant homeostasis, resulting in progressive accumulation of surfactant lipids and proteins in the alveolar space, labored breathing, and a reduced lifespan. GPR116 expression analysis, bone marrow transplantation studies, and characterization of conditional knockout mice revealed that GPR116 expression in ATII cells is required for maintaining normal surfactant levels. Aberrant packaging of surfactant proteins with lipids in the Gpr116 mutant mice resulted in compromised surfactant structure, function, uptake, and processing. Thus, GPR116 plays an indispensable role in lung surfactant homeostasis with important ramifications for the understanding and treatment of lung surfactant disorders.

  3. COST Action TU1208 - Working Group 4 - Combined use of GPR and other NDT methods & GPR applications in geosciences

    Science.gov (United States)

    Pajewski, Lara; Solla, Mercedes; Fontul, Simona

    2017-04-01

    This work aims at presenting the main results achieved by Working Group (WG) 4 "Different applications of GPR and other NDT technologies in civil engineering" of the COST (European COoperation in Science and Technology) Action TU1208 "Civil Engineering Applications of Ground Penetrating Radar" (www.GPRadar.eu, www.cost.eu). The main objective of the Action TU1208, started in April 2013 and ending in October 2017, is to exchange and increase scientific-technical knowledge and experience of Ground Penetrating Radar (GPR) techniques in civil engineering, whilst promoting in Europe the effective use of this safe non-destructive technique. The Action involves more than 150 Institutions from 28 COST Countries, a Cooperating State, 6 Near Neighbour Countries and 6 International Partner Countries. WG4 deals with the use of GPR outside from the civil engineering area, namely in archaeological prospecting and cultural heritage diagnostics, agriculture and management of water resources, investigation of polluted industrial sites, non-destructive testing of living tree trunks, planetary exploration, demining, localization of people buried under avalanches and debris, and more. Furthermore, this WG studies the integration of GPR with other Non-Destructive Testing (NDT) methods. The most relevant achievements stemming from WG4 will be presented during the 2017 EGU GA. These are: (i) The collection of thorough information on the state-of-the-art, ongoing studies, problems and future research needs on the topics of interest for this WG; (ii) The performance of a plethora of interesting case studies in important sites all over Europe, including well-known historical places such as Stonehenge (United Kingdom), Carnuntum (Austria), the Wawel Cathedral (Cracow, Poland), the Tholos Tomb of Acharnon (Athens, Greece), the Łazienki Royal Palace (Warsaw, Poland), and more; (iii) WG4 contributed to the TU1208 Education Pack, an open educational package conceived to teach GPR in University

  4. Pipe inspection using the pipe crawler. Innovative technology summary report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-01

    The US Department of Energy (DOE) continually seeks safer and more cost-effective remediation technologies for use in the decontamination and decommissioning (D and D) of nuclear facilities. In several of the buildings at the Fernald Site, there is piping that was used to transport process materials. As the demolition of these buildings occur, disposal of this piping has become a costly issue. Currently, all process piping is cut into ten-foot or less sections, the ends of the piping are wrapped and taped to prevent the release of any potential contaminants into the air, and the piping is placed in roll off boxes for eventual repackaging and shipment to the Nevada Test Site (NTS) for disposal. Alternatives that allow for the onsite disposal of process piping are greatly desired due to the potential for dramatic savings in current offsite disposal costs. No means is currently employed to allow for the adequate inspection of the interior of piping, and consequently, process piping has been assumed to be internally contaminated and thus routinely disposed of at NTS. The BTX-II system incorporates a high-resolution micro color camera with lightheads, cabling, a monitor, and a video recorder. The complete probe is capable of inspecting pipes with an internal diameter (ID) as small as 1.4 inches. By using readily interchangeable lightheads, the same system is capable of inspecting piping up to 24 inches in ID. The original development of the BTX system was for inspection of boiler tubes and small diameter pipes for build-up, pitting, and corrosion. However, the system is well suited for inspecting the interior of most types of piping and other small, confined areas. The report describes the technology, its performance, uses, cost, regulatory and policy issues, and lessons learned.

  5. Pipe inspection using the pipe crawler. Innovative technology summary report

    International Nuclear Information System (INIS)

    1999-05-01

    The US Department of Energy (DOE) continually seeks safer and more cost-effective remediation technologies for use in the decontamination and decommissioning (D and D) of nuclear facilities. In several of the buildings at the Fernald Site, there is piping that was used to transport process materials. As the demolition of these buildings occur, disposal of this piping has become a costly issue. Currently, all process piping is cut into ten-foot or less sections, the ends of the piping are wrapped and taped to prevent the release of any potential contaminants into the air, and the piping is placed in roll off boxes for eventual repackaging and shipment to the Nevada Test Site (NTS) for disposal. Alternatives that allow for the onsite disposal of process piping are greatly desired due to the potential for dramatic savings in current offsite disposal costs. No means is currently employed to allow for the adequate inspection of the interior of piping, and consequently, process piping has been assumed to be internally contaminated and thus routinely disposed of at NTS. The BTX-II system incorporates a high-resolution micro color camera with lightheads, cabling, a monitor, and a video recorder. The complete probe is capable of inspecting pipes with an internal diameter (ID) as small as 1.4 inches. By using readily interchangeable lightheads, the same system is capable of inspecting piping up to 24 inches in ID. The original development of the BTX system was for inspection of boiler tubes and small diameter pipes for build-up, pitting, and corrosion. However, the system is well suited for inspecting the interior of most types of piping and other small, confined areas. The report describes the technology, its performance, uses, cost, regulatory and policy issues, and lessons learned

  6. Underground docking of shields for the first time under the sea by MSD method. Shield for a gas pipe line to Shin Nagoya thermal power station of Chubu Electric Power Co. Ltd.,; Kaiteika hatsu no MSD koho ni yoru shirudo chichu setsugo. Chubu Denryoku Shin Nagoya Karyoku Hatsudensho gas dokan shirudo koji

    Energy Technology Data Exchange (ETDEWEB)

    Kobayashi, Y. [Shimizu Corp., Tokyo (Japan)

    1997-04-25

    MSD (mechanical shield docking) method is a method for mechanical docking two shields which have been extended simultaneously from both ends of one section of tunnel boring to shorten work term. One of the two shields has a piercing ring on its tip and another has a receiving ring. In the final stage of boring, the two ring are docked directly by piercing-receiving. The MSD method has been applied for the first time under sea to a boring work of an under sea tunnel on a route of a gas pipe line from Chita LNG base, Aichi prefecture to the title power station. This paper reports the outline of the shield machine and horizontal boring for confirming shield position that is a key to an underground docking as well as docking work. In the horizontal boring, after the shield machine on receiving side had reached the docking point predestined, the shield machine on piercing side conducted primary boring at 20 m front of the docking point and then secondary boring at 3 m front, whereby the boring hole was pierced into the shield machine on the receiving side. The accomplishment of this work made certain the reliability of MSD method even under sea. 1 ref., 13 figs., 3 tabs.

  7. A Label Propagation Approach for Detecting Buried Objects in Handheld GPR Data

    Science.gov (United States)

    2016-04-17

    16. SECURITY CLASSIFICATION OF: Detection of buried landmines and other explosive objects using ground penetrating radar ( GPR ) has been...Unfortunately, even though unlabeled GPR data may be abundant, labeled data are often available in 1. REPORT DATE (DD-MM-YYYY) 4. TITLE AND...public release; distribution is unlimited. A Label Propagation Approach for Detecting Buried Objectsin Handheld GPR Data The views, opinions and/or

  8. Estradiol-mediated ERK phosphorylation and apoptosis in vascular smooth muscle cells requires GPR 30.

    Science.gov (United States)

    Ding, Qingming; Gros, Robert; Limbird, Lee E; Chorazyczewski, Jozef; Feldman, Ross D

    2009-11-01

    Recent studies suggest that the rapid and nongenomic effects of estradiol may be mediated through the G protein-coupled receptor dubbed GPR30 receptor. The present study examines the role of GPR30 versus a classical estrogen receptor (ERalpha) in mediating the growth regulatory effects of estradiol. GPR30 is readily detectable in freshly isolated vascular tissue but barely detectable in cultured vascular smooth muscle cells (VSMC). In freshly isolated aortic tissue, estradiol stimulated extracellular signal-regulated kinases (ERK) phosphorylation. In contrast, in cultured VSMC, where GPR30 expression is significantly reduced, estradiol inhibits ERK phosphorylation. Transfer of the genes encoding GPR30 led to estradiol stimulation of ERK phosphorylation, which is opposite the effects of estradiol in the primary culture of VSMCs. Transduction of the mineralocorticoid receptor (MR) had no effect on estradiol effects on ERK. Estradiol-mediated stimulation of ERK subsequent to heterologous GPR30 expression was pertussis toxin sensitive and phosphoinositide 3-kinase (PI3 kinase) dependent; under these conditions, estradiol also inhibited protein kinase A (PKA). In contrast, in the absence of GPR30 expression in cultured VSMC, estradiol stimulated PKA activity and inhibited ERK phosphorylation. To determine the functional effect of GPR30 (vs. estrogen receptor expression), we assessed estradiol-mediated apoptosis. In the absence of GPR30 expression, estradiol inhibited apoptosis. This effect was enhanced with ERalpha expression. In contrast, with GPR30 expression, estradiol stimulated apoptosis in an ERK-dependent manner. Thus the effect of estradiol on vascular smooth muscle cell apoptosis is likely dependent on the balance between ER-mediated PKA activation and GPR30-mediated PKA inhibition and PI3 kinase activation. Taken together, we postulate that modulation of GPR30 expression or activity may be an important determinant of the effects of estradiol in the vasculature.

  9. A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice.

    Science.gov (United States)

    Oh, Da Young; Walenta, Evelyn; Akiyama, Taro E; Lagakos, William S; Lackey, Denise; Pessentheiner, Ariane R; Sasik, Roman; Hah, Nasun; Chi, Tyler J; Cox, Jason M; Powels, Mary Ann; Di Salvo, Jerry; Sinz, Christopher; Watkins, Steven M; Armando, Aaron M; Chung, Heekyung; Evans, Ronald M; Quehenberger, Oswald; McNelis, Joanne; Bogner-Strauss, Juliane G; Olefsky, Jerrold M

    2014-08-01

    It is well known that the ω-3 fatty acids (ω-3-FAs; also known as n-3 fatty acids) can exert potent anti-inflammatory effects. Commonly consumed as fish products, dietary supplements and pharmaceuticals, ω-3-FAs have a number of health benefits ascribed to them, including reduced plasma triglyceride levels, amelioration of atherosclerosis and increased insulin sensitivity. We reported that Gpr120 is the functional receptor for these fatty acids and that ω-3-FAs produce robust anti-inflammatory, insulin-sensitizing effects, both in vivo and in vitro, in a Gpr120-dependent manner. Indeed, genetic variants that predispose to obesity and diabetes have been described in the gene encoding GPR120 in humans (FFAR4). However, the amount of fish oils that would have to be consumed to sustain chronic agonism of Gpr120 is too high to be practical, and, thus, a high-affinity small-molecule Gpr120 agonist would be of potential clinical benefit. Accordingly, Gpr120 is a widely studied drug discovery target within the pharmaceutical industry. Gpr40 is another lipid-sensing G protein-coupled receptor, and it has been difficult to identify compounds with a high degree of selectivity for Gpr120 over Gpr40 (ref. 11). Here we report that a selective high-affinity, orally available, small-molecule Gpr120 agonist (cpdA) exerts potent anti-inflammatory effects on macrophages in vitro and in obese mice in vivo. Gpr120 agonist treatment of high-fat diet-fed obese mice causes improved glucose tolerance, decreased hyperinsulinemia, increased insulin sensitivity and decreased hepatic steatosis. This suggests that Gpr120 agonists could become new insulin-sensitizing drugs for the treatment of type 2 diabetes and other human insulin-resistant states in the future.

  10. Failure rate of piping in hydrogen sulphide systems

    International Nuclear Information System (INIS)

    Hare, M.G.

    1993-08-01

    The objective of this study is to provide information about piping failures in hydrogen sulphide service that could be used to establish failures rates for piping in 'sour service'. Information obtained from the open literature, various petrochemical industries and the Bruce Heavy Water Plant (BHWP) was used to quantify the failure analysis data. On the basis of this background information, conclusions from the study and recommendations for measures that could reduce the frequency of failures for piping systems at heavy water plants are presented. In general, BHWP staff should continue carrying out their present integrity and leak detection programmes. The failure rate used in the safety studies for the BHWP appears to be based on the rupture statistics for pipelines carrying sweet natural gas. The failure rate should be based on the rupture rate for sour gas lines, adjusted for the unique conditions at Bruce

  11. Study of a rehabilitated road using GPR and FWD

    Science.gov (United States)

    Marecos, Vania; Fontul, Simona; de Lurdes Antunes, Maria; Solla, Mercedes; Pajewski, Lara

    2017-04-01

    This work focus on the structural evaluation of a rehabilitated road after the conclusion of the first phase of the improvement works. The activities developed in the study comprised the characterization of the pavement layers condition (before the application of the asphalt surface layer) and the prediction of the pavement bearing capacity (taking into account the contribution of the wearing course, to be placed in accordance with the project specifications). For this study two non-destructive tests (NDT) were combined: Falling Weight Deflectometer (FWD) and Ground Penetrating Radar (GPR). The original pavement was essentially composed by a granular layer treated with a bituminous emulsion. The main objectives of the rehabilitation works were the enlargement of the road platform in selected locations, with the construction of a new pavement, and also the reinforcement of the existing pavement to increase its bearing capacity. The FWD tests were performed to assess the bearing capacity of the pavement and were conducted along the outer wheel path, in both directions. The spacing between measurement points was 75 m and the applied impulse load was 50 kN. The results showed a great variability of the deflections measured along the section under study. A preliminary zonation of the pavement was carried out, and was latter adjusted based on the results of the GPR. To determine the thickness of the pavement layers a GPR survey was carried out using a 1.8 GHz antenna and a radar control unit SIR-20, both from GSSI. The GPR tests were performed continuously along the same line as the FWD tests. The GPR tests allowed for the identification of the different structures of the pavement, corresponding to the zones with the new pavement and the existing pavement with reinforcement. Some cores were extracted to calibrate the thickness of the GPR bituminous layers, to verify the conditions of adhesion between layers and also to perform laboratory tests to characterize the

  12. Character of GPR wave in air and processed method

    International Nuclear Information System (INIS)

    Shi Jianping; Zhang Zhiyong; Deng Juzhi

    2009-01-01

    The wave reflected by objects in the air is unavoidable because electromagnetic wave of GPR was send to all directions. There are three air reflection types: directly arrived wave, system ring and reflection wave. The directly arrived waves don't disturb the recognition of the reflections from earth because they affect the first short time of GPR trace record. But system ring and reflection from air are the mainly part of disturbs. The time and distance curve of reflection from air can be classified into two types: hyperbola type and line type. The reflection from air and from earth can be recognized by calculating the velocity of electromagnetic wave. Line type reflection can be filtered by background remove and 2-D filter; by comparing the migrated profiles with velocity in air and ground, the interpretation will become more exact. (authors)

  13. Pipe support program at Pickering

    International Nuclear Information System (INIS)

    Sahazizian, L.A.; Jazic, Z.

    1997-01-01

    This paper describes the pipe support program at Pickering. The program addresses the highest priority in operating nuclear generating stations, safety. We present the need: safety, the process: managed and strategic, and the result: assurance of critical piping integrity. In the past, surveillance programs periodically inspected some systems, equipment, and individual components. This comprehensive program is based on a managed process that assesses risk to identify critical piping systems and supports and to develop a strategy for surveillance and maintenance. The strategy addresses all critical piping supports. Successful implementation of the program has provided assurance of critical piping and support integrity and has contributed to decreasing probability of pipe failure, reducing risk to worker and public safety, improving configuration management, and reducing probability of production losses. (author)

  14. Eulerian-Lagrangian simulation of non-isothermal gas-solid flows: particle-turbulence interactions in pipe flows; Simulation eulerienne-lagrangienne d'ecoulements gaz-solide non isothermes: interactions particules-turbulence, application aux ecoulements en conduite

    Energy Technology Data Exchange (ETDEWEB)

    Chagras, V.

    2004-03-15

    The aim of this work is to contribute to the numerical modeling of turbulent gas-solid flows in vertical or horizontal non isothermal pipes, which can be found in many industrial processes (pneumatic transport, drying, etc). The model is based on an Eulerian-Lagrangian approach allowing a fine description of the interactions between the two phases (action of the fluid upon the particles (dispersion), action of the particles upon the fluid (two way coupling) and between particles (collisions)), more or less influential according to the characteristics of the flow. The influence of the gas phase turbulence on the particle motion is taken into account using a non-isotropic dispersion model, which allows the generation of velocity and temperature fluctuations of the fluid seen by the particles. The numerical developments brought to the model for vertical and horizontal pipe flow have been validated by comparison with available experimental results from the literature. The sensitivity tests highlight the influence of the dispersion model, collisions and turbulence modulation (direct and non direct modifications ) on the dynamic and thermal behavior of the suspension. The model is able to predict the heat exchanges in the presence of particles for a wide range of flows in vertical and horizontal pipes. However numerical problems still exist in two-way coupling for very small particles and loading ratios above one. This is related to the problems encountered when modeling the coupling terms between the two phases (parameters C{sub {epsilon}}{sub 2} and C{sub {epsilon}}{sub 3} ) involved in the turbulence dissipation balance. (author)

  15. Lactate produced during labor modulates uterine inflammation via GPR81 (HCA1).

    Science.gov (United States)

    Madaan, Ankush; Nadeau-Vallée, Mathieu; Rivera, Jose Carlos; Obari, Dima; Hou, Xin; Sierra, Estefania Marin; Girard, Sylvie; Olson, David M; Chemtob, Sylvain

    2017-01-01

    Uterine inflammatory processes trigger prolabor pathways and orchestrate on-time labor onset. Although essential for successful labor, inflammation needs to be regulated to avoid uncontrolled amplification and resolve postpartum. During labor, myometrial smooth muscle cells generate ATP mainly via anaerobic glycolysis, resulting in accumulation of lactate. Aside from its metabolic function, lactate has been shown to activate a G protein-coupled receptor, GPR81, reported to regulate inflammation. We therefore hypothesize that lactate produced during labor may act via GPR81 in the uterus to exert in a feedback manner antiinflammatory effects, to resolve or mitigate inflammation. We sought to investigate the role of lactate produced during labor and its receptor, GPR81, in regulating inflammation in the uterus. We investigated the expression of GPR81 in the uterus and the pharmacological role of lactate acting via GPR81 during labor, using shRNA-GPR81 and GPR81 -/- mice. (1) Uterine lactate levels increased substantially from 2 to 9 mmol/L during labor. (2) Immunohistological analysis revealed expression of GPR81 in the uterus with high expression in myometrium. (3) GPR81 expression increased during gestation, and peaked near labor. (4) In primary myometrial smooth muscle cell and ex vivo uteri from wild-type mice, lactate decreased interleukin-1β-induced transcription of key proinflammatory Il1b, Il6, Ccl2, and Pghs2; suppressive effects of lactate were not observed in cells and tissues from GPR81 -/- mice. (5) Conversely, proinflammatory gene expression was augmented in the uterus at term in GPR81 -/- mice and wild-type mice treated intrauterine with lentiviral-encoded shRNA-GPR81; GPR81 silencing also induced proinflammatory gene transcription in the uterus when labor was induced by endotoxin (lipopolysaccharide). (6) Importantly, administration to pregnant mice of a metabolically stable specific GPR81 agonist, 3,5-dihydroxybenzoic acid, decreased endotoxin

  16. Double-Sided Sliding-Paraboloid (DSSP): A new tool for preprocessing GPR data

    Science.gov (United States)

    Rashed, Mohamed; Rashed, Essam A.

    2017-05-01

    Background noise in Ground Penetrating Radar (GPR) data is a nagging problem that degrades the quality of GPR images and increases their ambiguity. There are several methods adopting different strategies to remove background noise. In this study, we present the Double-Sided Sliding-Paraboloid (DSSP) as a new background removal technique. Experiments conducted on field GPR data show that the proposed DSSP technique has several advantages over existing background removal techniques. DSSP removes background noise more efficiently while preserving first arrivals and other strong horizontal reflections. Moreover, DSSP introduces no artifacts to GPR data and corrects data for DC-shift and wow noise.

  17. Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling.

    Science.gov (United States)

    Bachmann, Verena A; Mayrhofer, Johanna E; Ilouz, Ronit; Tschaikner, Philipp; Raffeiner, Philipp; Röck, Ruth; Courcelles, Mathieu; Apelt, Federico; Lu, Tsan-Wen; Baillie, George S; Thibault, Pierre; Aanstad, Pia; Stelzl, Ulrich; Taylor, Susan S; Stefan, Eduard

    2016-07-12

    Scaffolding proteins organize the information flow from activated G protein-coupled receptors (GPCRs) to intracellular effector cascades both spatially and temporally. By this means, signaling scaffolds, such as A-kinase anchoring proteins (AKAPs), compartmentalize kinase activity and ensure substrate selectivity. Using a phosphoproteomics approach we identified a physical and functional connection between protein kinase A (PKA) and Gpr161 (an orphan GPCR) signaling. We show that Gpr161 functions as a selective high-affinity AKAP for type I PKA regulatory subunits (RI). Using cell-based reporters to map protein-protein interactions, we discovered that RI binds directly and selectively to a hydrophobic protein-protein interaction interface in the cytoplasmic carboxyl-terminal tail of Gpr161. Furthermore, our data demonstrate that a binary complex between Gpr161 and RI promotes the compartmentalization of Gpr161 to the plasma membrane. Moreover, we show that Gpr161, functioning as an AKAP, recruits PKA RI to primary cilia in zebrafish embryos. We also show that Gpr161 is a target of PKA phosphorylation, and that mutation of the PKA phosphorylation site affects ciliary receptor localization. Thus, we propose that Gpr161 is itself an AKAP and that the cAMP-sensing Gpr161:PKA complex acts as cilium-compartmentalized signalosome, a concept that now needs to be considered in the analyzing, interpreting, and pharmaceutical targeting of PKA-associated functions.

  18. Towards Novel Techniques for Root Phenotyping Using GPR

    Science.gov (United States)

    Kobylinski, C.; Neely, H.; Everett, M. E.; Hays, D. B.; Lewis, K.

    2017-12-01

    The ability to phenotype roots in situ would provide information for carbon sequestration potential through increased root mass, possible water-seeking strategies by plants, and generate data for plant breeders. One technique for root phenotyping is to measure differences in soil moisture and use this data to infer root presence or absence. Current technologies for soil moisture detection include electromagnetic induction and neutron moisture meters; however, ground penetrating radar (GPR) has been suggested to monitor root phenotypes. The objective of this study is to use GPR as a novel technique for detecting roots and classifying root phenotypes based on the detection of differences in dielectric permittivity in response to changes in soil water content. The study will be conducted at two sites in Texas: Thrall, TX (Burleson clay) and Lubbock, TX (Olton clay loam). Three root types will be investigated: fibrous (grain sorghum), tap root (cowpea), and mixed (9-species). Data will be collected along a 10 m linear transect in each plot with a PulseEkko GPR bi-static unit operating at a radio frequency of 500 MHz. Additionally, an EM38-MK2 survey will be performed along each transect. Soil surface moisture readings will be collected with a ML3 ThetaProbe soil moisture sensor and a neutron moisture meter will be used to obtain soil moisture measurements down to 1.2 m. Measurements will be collected every two weeks throughout the growing season. Soil properties including particle size distribution, cation exchange capacity, and bulk density will also be measured. GPR's ability to distinguish root types across soils will be assessed.

  19. Regional processing of GPR data in an imperfect world

    Science.gov (United States)

    Yu, Ssu-Hsin; Mehra, Raman K.

    2004-09-01

    Designing robust landmine detection algorithms for ground penetrating radar (GPR) remains a challenging task due to variations of environmental conditions and diverse clutter objects in the soil, among others. The problem is aggravated for handheld systems by introducing operator motion and by the position uncertainty. Even though aggregating consecutive GPR samples to form multi-sample features seems to be an intuitively sensible approach to improve Pd/Pf, determining multi-sample features that are robust to the operator motion and position uncertainty is a formidable task. In this paper, we propose an ATR method to identify mines based on handheld GPR data collected for regional processing, where systematic operator motion is required and perhaps some position information is collected along with the data. The regional processing is intended to be conducted after other initial detection methods have identified an area for further interrogation. In this study, we will use GPR data that were collected by a robotic arm. In order for the developed ATR method to be applicable to data collected by human operators, which have greater position uncertainty, we focus on features that can still be used either directly or with minor modification when accurate sensor positions are not available. We tested two classes of classifiers, Support Vector Machines (SVM) and Gaussian Mixtures (GM). For both classifiers, less complex forms of the classifiers outperform those with more complicated structures. The reason is that the training set is relatively small compared to the diversity of the mines and the clutter objects in the training set.

  20. Characterisation of carbonate rocks from near-surface cross-hole and reflection GPR investigations - A case study from southeast Zealand, Denmark

    DEFF Research Database (Denmark)

    Nielsen, Lars; Looms, Majken Caroline; Hansen, Thomas Mejer

    Carbonates found in the near-surface of southeast Zealand, eastern Denmark, are analogous to deposits serving as groundwater and hydrocarbon reservoirs in the Danish region. The study site is located in the Boesdal limestone quarry. A 20 by 20 m area of the bottom of the quarry was levelled using...... successful in generating well-defined statistical parameters for the GPR velocity field of the subsurface than the typical strategy in which the total rock section covered by the cross-hole data is regarded as the same type of medium. Modelling strategies in which porosity data from the boreholes...... are included in the inversion algorithm are tested and compared to the results obtained using the more traditional approaches. The GPR investigations may contribute to setting the framework for future fine-grained models designed to simulate fluid and gas flow in groundwater and hydrocarbon reservoirs....

  1. A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C elegans.

    Science.gov (United States)

    Srinivasan, Dayalan G; Fisk, Ridgely M; Xu, Huihong; van den Heuvel, Sander

    2003-05-15

    The Caenorhabditis elegans coiled-coil protein LIN-5 mediates several processes in cell division that depend on spindle forces, including alignment and segregation of chromosomes and positioning of the spindle. Here, we describe two closely related proteins, GPR-1 and GPR-2 (G protein regulator), which associate with LIN-5 in vivo and in vitro and depend on LIN-5 for localization to the spindle and cell cortex. GPR-1/GPR-2 contain a GoLoco/GPR motif that mediates interaction with GDP-bound Galpha(i/o). Inactivation of lin-5, gpr-1/gpr-2, or the Galpha(i/o) genes goa-1 and gpa-16 all cause highly similar chromosome segregation and spindle positioning defects, indicating a positive role for the LIN-5 and GPR proteins in G protein signaling. The lin-5 and gpr-1/gpr-2 genes appear to act downstream of the par polarity genes in the one- and two-cell stages and downstream of the tyrosine kinase-related genes mes-1 and src-1 at the four-cell stage. Together, these results indicate that GPR-1/GPR-2 in association with LIN-5 activate G protein signaling to affect spindle force. Polarity determinants may regulate LIN-5/GPR/Galpha locally to create the asymmetric forces that drive spindle movement. Results in C. elegans and other species are consistent with a novel model for receptor-independent activation of Galpha(i/o) signaling.

  2. Disposal of iron tailings in reservoirs: a GPR application

    Directory of Open Access Journals (Sweden)

    Rachel Jardim Martini

    2016-11-01

    Full Text Available A large volume of waste is generated by iron mining in Brazil, and the amount has been rapidly increasing. The waste is usually stored in large piles or in reservoirs formed by tailings dams, which occupy large areas in the mining complex. The limitation of natural resources and of new areas for waste disposal has led to change in paradigms. This study therefore aimed to apply a geophysical technique, known as Ground Penetrating Radar (GPR, in order to define sedimentation patterns in the subsurface reservoir created by Diogo's tailings dam in Rio Piracicaba in Minas Gerais, Brazil. To assist the recognition of patterns captured by the GPR, subsurface material samples were collected and analyzed for mineralogical composition, moisture content, electrical conductivity, mineralogical analysis, particle size, X-Ray Diffraction and X-Ray Fluorescence. The results indicated that areas with tailings that had high concentrations of hematite (around 60% in the mineralogical analysis altered the reflection patterns. The presence of water generated some multiple reflections, which were less significant in shallower sites with more waste and more significant in deeper sites with less waste. In general, the application of the GPR was feasible in aquatic environments with rich subsurface hematite deposits.

  3. Automated GPR Rebar Analysis for Robotic Bridge Deck Evaluation.

    Science.gov (United States)

    Kaur, Parneet; Dana, Kristin J; Romero, Francisco A; Gucunski, Nenad

    2016-10-01

    Ground penetrating radar (GPR) is used to evaluate deterioration of reinforced concrete bridge decks based on measuring signal attenuation from embedded rebar. The existing methods for obtaining deterioration maps from GPR data often require manual interaction and offsite processing. In this paper, a novel algorithm is presented for automated rebar detection and analysis. We test the process with comprehensive measurements obtained using a novel state-of-the-art robotic bridge inspection system equipped with GPR sensors. The algorithm achieves robust performance by integrating machine learning classification using image-based gradient features and robust curve fitting of the rebar hyperbolic signature. The approach avoids edge detection, thresholding, and template matching that require manual tuning and are known to perform poorly in the presence of noise and outliers. The detected hyperbolic signatures of rebars within the bridge deck are used to generate deterioration maps of the bridge deck. The results of the rebar region detector are compared quantitatively with several methods of image-based classification and a significant performance advantage is demonstrated. High rates of accuracy are reported on real data that includes thousands of individual hyperbolic rebar signatures from three real bridge decks.

  4. Identification of buried victims in natural disaster with GPR method

    Science.gov (United States)

    Dewi, Rianty Kusuma; Kurniawan, Adityo; Taqwantara, Reyhan Fariz; Iskandar, Farras M.; Naufal, Taufiq Ziyan; Widodo

    2017-07-01

    Indonesian is one of the most seismically active regions in the world and has very complicated plate convergence because there is meeting point of several tectonic plates. The complexity of tectonic features causes a lot of natural disasters such as landslides, tsunamis, earth quakes, volcanoes eruption, etc. Sometimes, the disasters occurs in high populated area and causing thousands to millions of victim been buried under the rumble. Unfortunately, the evacuation still uses the conventional method such using rescue dogs whereas the sensitivity of smell is decrease when the victims buried under the level of the ground. The purpose of this study is to detect buried bodies using GPR method, so it can enhance the effectiveness and the efficiency in looking for the disaster victims. GPR method is used because it can investigate things under the ground. A detailed GPR research has been done in Cikutra Graveyard, Bandung, with corpse buried two week until two years before the research. The radar profiles from this research showed amplitude contras anomaly between the new corpse and the old ones. We obtained the amplitude contras at 1.2-1.4 meters under the surface. This method proved to be effective but still need more attention on undulated surface and non-soil areas.

  5. Numerical modelling of GPR electromagnetic fields for locating burial sites

    Science.gov (United States)

    Carcione, José M.; Karczewski, Jerzy; Mazurkiewicz, Ewelina; Tadeusiewicz, Ryszard; Tomecka-Suchoń, Sylwia

    2017-11-01

    Ground-penetrating radar (GPR) is commonly used for locating burial sites. In this article, we acquired radargrams at a site where a domestic pig cadaver was buried. The measurements were conducted with the ProEx System GPR manufactured by the Swedish company Mala Geoscience with an antenna of 500MHz. The event corresponding to the pig can be clearly seen in the measurements. In order to improve the interpretation, the electromagnetic field is compared to numerical simulations computed with the pseudo-spectral Fourier method. A geological model has been defined on the basis of assumed electromagnetic properties (permittivity, conductivity and magnetic permeability). The results, when compared with the GPR measurements, show a dissimilar amplitude behaviour, with a stronger reflection event from the bottom of the pit. We have therefore performed another simulation by decreasing the electrical conductivity of the body very close to that of air. The comparison improved, showing more reflections, which could be an indication that the body contains air or has been degraded to a certain extent that the electrical resistivity has greatly increased.

  6. GPR143 gene mutation analysis in pediatric patients with albinism.

    Science.gov (United States)

    Trebušak Podkrajšek, Katarina; Stirn Kranjc, Branka; Hovnik, Tinka; Kovač, Jernej; Battelino, Tadej

    2012-09-01

    X-linked ocular albinism type 1 is difficult to differentiate clinically from other forms of albinism in young patients. X-linked ocular albinism type 1 is caused by mutations in the GPR143 gene, encoding melanosome specific G-protein coupled receptor. Patients typically present with moderately to severely reduced visual acuity, nystagmus, strabismus, photophobia, iris translucency, hypopigmentation of the retina, foveal hypoplasia and misrouting of optic nerve fibers at the chiasm. Following clinical ophthalmological evaluation, GPR143 gene mutational analyses were performed in a cohort of 15 pediatric male patients with clinical signs of albinism. Three different mutations in the GPR143 gene were identified in four patients, including a novel c.886G>A (p.Gly296Arg) mutation occurring "de novo" and a novel intronic c.360 + 5G>A mutation, identified in two related boys. Four patients with X-linked ocular albinism type 1 were identified from a cohort of 15 boys with clinical signs of albinism using mutation detection methods. Genetic analysis offers the possibility of early definitive diagnosis of ocular albinism type 1 in a significant portion of boys with clinical signs of albinism.

  7. Choice of insulation standard for pipe networks in 4th generation district heating systems

    DEFF Research Database (Denmark)

    Lund, Rasmus Søgaard; Mohammadi, Soma

    2016-01-01

    and smart gas grids. Improving DH pipes by improving the insulation standard results in decreasing the heat and temperature losses from the pipe networks. When reducing heat losses from DH pipes, there is a trade-off between the increasing cost of pipe insulation and the associated savings in the heat...... by implementing different pipe insulation standards. In the second step, the specific grid losses found in the first step are analysed in an integrated energy systems model where all main energy sectors and their interrelations are included. The outcome of the study can provide decision support when planning...... investments in DH systems today and in the future. The results from the case of Denmark shows that pipes with higher insulation standard (series 3) is generally preferable, but the highest insulation standard available today (series 4) might be preferable in the future if fuel prices or increase or investment...

  8. An experimental study of naturally driven heated air flow in a vertical pipe

    Energy Technology Data Exchange (ETDEWEB)

    Rahimi, Mostafa; Bayat, Mohammad Mehdi [Department of Mechanical Engineering, University of Mohaghegh Ardabili, Ardabil (Iran, Islamic Republic of)

    2011-01-15

    Specifications of warm air flow within a vertical pipe which is induced by the buoyancy effect were investigated in this study. Air from surroundings was directed into a heating chamber connected to a vertical pipe to establish a flow within the pipe. The temperature and the velocity were measured at different points within the stable flow and the mean values of these parameters were computed. Mass flow rate of air was evaluated using ideal gas assumption. In order to investigate the effect of the thermal boundary condition of the pipe, two tests were conducted; once for the pipe exposed to the surroundings and then for the pipe with a thermal insulation. A model for predicting the induced flow rate of warm air was developed and the predictions of the model were compared with the experimental data over the tested range of the parameters. (author)

  9. Stress analysis of the O-element pipe during the process of flue gases purification

    Directory of Open Access Journals (Sweden)

    Nekvasil R.

    2008-11-01

    Full Text Available Equipment for flue gases purification from undesired substances is used throughout power and other types of industry. This paper deals with damaging of the O-element pipe designed to remove sulphur from the flue gases, i.e. damaging of the pipe during flue gases purification. This purification is conducted by spraying the water into the O-shaped pipe where the flue gases flow. Thus the sulphur binds itself onto the water and gets removed from the flue gas. Injection of cold water into hot flue gases, however, causes high stress on the inside of the pipe, which can gradually damage the O-element pipe. In this paper initial injection of water into hot pipe all the way to stabilization of temperature fields will be analyzed and the most dangerous places which shall be considered for fatigue will be determined.

  10. Research on Buckling State of Prestressed Fiber-Strengthened Steel Pipes

    Science.gov (United States)

    Wang, Ruheng; Lan, Kunchang

    2018-01-01

    The main restorative methods of damaged oil and gas pipelines include welding reinforcement, fixture reinforcement and fiber material reinforcement. Owing to the severe corrosion problems of pipes in practical use, the research on renovation and consolidation techniques of damaged pipes gains extensive attention by experts and scholars both at home and abroad. The analysis of mechanical behaviors of reinforced pressure pipelines and further studies focusing on “the critical buckling” and intensity of pressure pipeline failure are conducted in this paper, providing theoretical basis to restressed fiber-strengthened steel pipes. Deformation coordination equations and buckling control equations of steel pipes under the effect of prestress is deduced by using Rayleigh Ritz method, which is an approximation method based on potential energy stationary value theory and minimum potential energy principle. According to the deformation of prestressed steel pipes, the deflection differential equation of prestressed steel pipes is established, and the critical value of buckling under prestress is obtained.

  11. Water hammer in elastic pipes

    International Nuclear Information System (INIS)

    Gale, J.; Tiselj, I.

    2002-01-01

    One dimensional two-fluid six-equation model of two-phase flow, that can be found in computer codes like RELAP5, TRAC, and CATHARE, was upgraded with additional terms, which enable modelling of the pressure waves in elastic pipes. It is known that pipe elasticity reduces the propagation velocity of the shock and other pressure waves in the piping systems. Equations that include the pipe elasticty terms are used in WAHA code, which is being developed within the WAHALoads project of 5't'h EU research program.(author)

  12. Determination of ground structures of the Suleymaniye complex and the Selimiye madrasa with GPR in Damaskus-Syria

    Science.gov (United States)

    Kadioglu, Selma; Kadioglu, Yusuf K.

    2010-05-01

    of the pools in the Selimiye madrasa and Suleymaniye complex, arasta, and some special areas around the complex using 500 MHz shielded antennas. Secondly, the GPR data measurements were also carried out on spaced 1 m parallel profiles in the Suleymaniye mosque. The results showed that the first very shallow ductile layer was approximately 1 m thick and included some water pipes or drain pipes. The second layer was until 2.5 m depth and included buried human made structures in the Suleymaniye courtyard. They could be restoration traces in the early time or could be archaeological remains. The third layer was a more compact layer seen until the end of profile sections. However, it was seen on the profile section that third layer included more effective vertical fracture groups and some of them reached to the surface in the courtyard and the portico of the Selimiye madrasa. This result could be the reason of the deformation in the courtyard and the portico. There was no important anomaly in the profile sections of the Suleymaniye mosque to find the reason of the fractures on its dome. This study were supported by Turkish International Cooperation and Development Acency (TIKA) and Earth Sciences Application and Research Center of Ankara University (YEBIM).

  13. 46 CFR 34.15-15 - Piping-T/ALL.

    Science.gov (United States)

    2010-10-01

    ... with drains or other openings within such spaces. (j) Installation test requirements are: (1) Upon completion of the piping installation, and before the cylinders are connected, a pressure test shall be applied as set forth in this paragraph. Only carbon dioxide or other inert gas shall be used for this test...

  14. Flow induced noise modelling for industrial piping systems

    NARCIS (Netherlands)

    Gijrath, H.; Ǎbom, M.

    2003-01-01

    Noise from e.g. gas-transport piping systems becomes more and more a problem for plants located close to urban areas. Too high noise levels are unacceptable and will put limitations on the plant capacity. Flow-induced noise of valves, orifices and headers installed in the installation plays a

  15. 49 CFR 192.309 - Repair of steel pipe.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Repair of steel pipe. 192.309 Section 192.309 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS...

  16. 49 CFR 192.311 - Repair of plastic pipe.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Repair of plastic pipe. 192.311 Section 192.311 Transportation Other Regulations Relating to Transportation (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS...

  17. Pulsed Eddy Current Sensing for Critical Pipe Condition Assessment.

    Science.gov (United States)

    Ulapane, Nalika; Alempijevic, Alen; Vidal Calleja, Teresa; Valls Miro, Jaime

    2017-09-26

    Pulsed Eddy Current (PEC) sensing is used for Non-Destructive Evaluation (NDE) of the structural integrity of metallic structures in the aircraft, railway, oil and gas sectors. Urban water utilities also have extensive large ferromagnetic structures in the form of critical pressure pipe systems made of grey cast iron, ductile cast iron and mild steel. The associated material properties render NDE of these pipes by means of electromagnetic sensing a necessity. In recent years PEC sensing has established itself as a state-of-the-art NDE technique in the critical water pipe sector. This paper presents advancements to PEC inspection in view of the specific information demanded from water utilities along with the challenges encountered in this sector. Operating principles of the sensor architecture suitable for application on critical pipes are presented with the associated sensor design and calibration strategy. A Gaussian process-based approach is applied to model a functional relationship between a PEC signal feature and critical pipe wall thickness. A case study demonstrates the sensor's behaviour on a grey cast iron pipe and discusses the implications of the observed results and challenges relating to this application.

  18. Neutron radiographic detection limits of fluids in metal pipes

    International Nuclear Information System (INIS)

    Winn, W.G.

    1976-01-01

    Routine maintenance of process pipes at the Savannah River Plant has indicated that undesirable fluids can build up in the various gas lines. Thermal neutron radiography has been used to image thin films of various fluids in thick-walled high-pressure process pipes. A 3.5 x 10 6 n/(cm 2 -sec) thermal neutron beam and standard transfer imaging techniques were used to provide radiographs of the fluid-bearing pipes. In addition, a computer graphics procedure was developed that simulated the neutron radiographs; this method permitted examination of some fluid-pipe configurations not studied experimentally. Actual pipe dimensions ranged in OD from 1 / 4 to 9 / 16 in. with OD/ID = 3. Many common industrial fluids such as H 2 O, oils, and CCl 4 may be detected in thick-walled process pipes, even when distributed in thin (3 to 10 mil) fluid films. By contrast, fluids with a low thermal neutron cross section (D 2 O and T 2 O) can be detected only for much thicker films

  19. Methodology for Life Testing of Refractory Metal / Sodium Heat Pipes

    International Nuclear Information System (INIS)

    Martin, James J.; Reid, Robert S.

    2006-01-01

    This work establishes an approach to generate carefully controlled data to find heat pipe operating life with material-fluid combinations capable of extended operation. To accomplish this goal acceleration is required to compress 10 years of operational life into 3 years of laboratory testing through a combination of increased temperature and mass fluence. Specific test series have been identified, based on American Society for Testing and Materials (ASTM) specifications, to investigate long-term corrosion rates. The refractory metal selected for demonstration purposes is a molybdenum-44.5% rhenium alloy formed by powder metallurgy. The heat pipes each have an annular crescent wick formed by hot isostatic pressing of molybdenum-rhenium wire mesh. The heat pipes are filled by vacuum distillation with purity sampling of the completed assembly. Round-the-clock heat pipe tests with 6-month destructive and non-destructive inspection intervals are conducted to identify the onset and level of corrosion. Non-contact techniques are employed to provide power to the evaporator (radio frequency induction heating at 1 to 5 kW per heat pipe) and calorimetry at the condenser (static gas gap coupled water cooled calorimeter). The planned operating temperature range extends from 1123 to 1323 K. Accomplishments before project cancellation included successful development of the heat pipe wick fabrication technique, establishment of all engineering designs, baseline operational test requirements, and procurement/assembly of supporting test hardware systems. (authors)

  20. Submarine slope failures due to pipe structure formation.

    Science.gov (United States)

    Elger, Judith; Berndt, Christian; Rüpke, Lars; Krastel, Sebastian; Gross, Felix; Geissler, Wolfram H

    2018-02-19

    There is a strong spatial correlation between submarine slope failures and the occurrence of gas hydrates. This has been attributed to the dynamic nature of gas hydrate systems and the potential reduction of slope stability due to bottom water warming or sea level drop. However, 30 years of research into this process found no solid supporting evidence. Here we present new reflection seismic data from the Arctic Ocean and numerical modelling results supporting a different link between hydrates and slope stability. Hydrates reduce sediment permeability and cause build-up of overpressure at the base of the gas hydrate stability zone. Resulting hydro-fracturing forms pipe structures as pathways for overpressured fluids to migrate upward. Where these pipe structures reach shallow permeable beds, this overpressure transfers laterally and destabilises the slope. This process reconciles the spatial correlation of submarine landslides and gas hydrate, and it is independent of environmental change and water depth.

  1. GPR37L1 modulates seizure susceptibility: Evidence from mouse studies and analyses of a human GPR37L1 variant.

    Science.gov (United States)

    Giddens, Michelle M; Wong, Jennifer C; Schroeder, Jason P; Farrow, Emily G; Smith, Brilee M; Owino, Sharon; Soden, Sarah E; Meyer, Rebecca C; Saunders, Carol; LePichon, J B; Weinshenker, David; Escayg, Andrew; Hall, Randy A

    2017-10-01

    Progressive myoclonus epilepsies (PMEs) are disorders characterized by myoclonic and generalized seizures with progressive neurological deterioration. While several genetic causes for PMEs have been identified, the underlying causes remain unknown for a substantial portion of cases. Here we describe several affected individuals from a large, consanguineous family presenting with a novel PME in which symptoms begin in adolescence and result in death by early adulthood. Whole exome analyses revealed that affected individuals have a homozygous variant in GPR37L1 (c.1047G>T [Lys349Asn]), an orphan G protein-coupled receptor (GPCR) expressed predominantly in the brain. In vitro studies demonstrated that the K349N substitution in Gpr37L1 did not grossly alter receptor expression, surface trafficking or constitutive signaling in transfected cells. However, in vivo studies revealed that a complete loss of Gpr37L1 function in mice results in increased seizure susceptibility. Mice lacking the related receptor Gpr37 also exhibited an increase in seizure susceptibility, while genetic deletion of both receptors resulted in an even more dramatic increase in vulnerability to seizures. These findings provide evidence linking GPR37L1 and GPR37 to seizure etiology and demonstrate an association between a GPR37L1 variant and a novel progressive myoclonus epilepsy. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Characterising pharmacological ligands to study the long chain fatty acid receptors GPR40/FFA1 and GPR120/FFA4

    DEFF Research Database (Denmark)

    Milligan, G; Alvarez-Curto, E; Watterson, K R

    2015-01-01

    by the same group of free fatty acids, FFA1 and FFA4 are not closely related and whilst the basis of recognition of fatty acids by FFA1 is similar to that of the short-chain fatty acid receptors FFA2 and FFA3, amino acid residues involved in endogenous ligand recognition by FFA4 are more akin to those......The G protein-coupled receptors FFA1 (previously designated GPR40) and FFA4 (previously GPR120) are both activated by saturated and unsaturated longer-chain free fatty acids. With expression patterns and functions anticipated to directly or indirectly promote insulin secretion, provide homeostatic...... control of blood glucose and improve tissue insulin sensitivity, both receptors are being studied as potential therapeutic targets for the control of type II diabetes. Furthermore, genetic and systems biology studies in both humans and mouse models link FFA4 to diabetes and obesity. Although activated...

  3. Pipe locator for imaging underground pipelines (abstract)

    Science.gov (United States)

    Miyamoto, Y.; Wasa, Y.; Mori, K.; Kondo, Y.

    1988-11-01

    Recently, it becomes more important to locate the complex piping patterns such as tee, bend, riser, and the others with high accuracy for maintenance and protection of city gas pipelines. Hence, we have developed a new pipe locator system for imaging the complex underground pipelines using magnetic remote sensing techniques. The main framework of this development is the application of the pattern recognition of the magnetic field distribution to the location of buried pipelines in urban areas. The first step for imaging the complex pipelines is to measure the three-dimensional magnetic field distribution with high accuracy which is generated by the passage of the alternating signal current through buried pipeline. For this purpose a portable trolley unit which is capable of scanning the ground to collect data, the 10 three-axes coil sensors with a sensitivity of 1 μG which are aligned in the unit, and a filter system using a FFT signal processor which eliminates urban magnetic noise as high as 10 mG in some cases, were developed. The second step is to process the magnetic field distribution data, to extract the feature of the underground pipeline using the contour diagram and the three-dimensional drawing of the magnetic field, and to identify the complex piping patterns. Further, we recognized that a nonlinear least-square method algorithm for calculation of the pipeline's position was useful to improve the location accuracy.

  4. Nondestructive testing during the fabrication of pressure vessels with half pipe jackets

    International Nuclear Information System (INIS)

    Scherner, D.

    1985-01-01

    The most important precondition to guarantee the optimum quality of half pipe jackets is the precise fixing and observance of the manufacturing conditions. For this reason the manufacturing conditions are explained in detail. The second important point is the test for gas tightness of the half pipe jacket system. The sources of mistakes in connection with the test for gas tightness are of fundamental importance. (orig./PW) [de

  5. Empirical prediction of mechanical properties of flexible pavement through GPR

    Science.gov (United States)

    Bianchini Ciampoli, Luca; Benedetto, Andrea

    2017-04-01

    To date, it is well known that the frequency of accidental events recorded on a road, is related to the deterioration rate of its pavement. In this sense, the monitoring of the pavement health over a road network is a crucial task for the administrations, to define a priority scale for maintenance works, and accordingly to lower the risk of accidents. Several studies suggest the possibility to employ Ground-penetrating Radar (GPR) to overcome the limits of traditional bearing tests, which due to their low productivity and high costs, can only give a discrete knowledge about the strength of the pavement. This work presents a GPR-based empirical model for the prediction of the bearing capacity of a road pavement, expressed as Young's Modulus. The model exploits the GPR to extract information on the thickness of the base course and the clay content, by referring to the signal velocity and attenuation, respectively. To test the effectiveness of the model, experimental activities have been accounted for. In particular, multi-frequency GPR tests have been performed along road sections of rural roads, composed of a flexible pavement, for a total of 45 Km. As ground-truth, light falling weight deflectometer (LFWD) and Curviameter have been employed. Both the electromagnetic and the mechanical datasets have been properly processed, in order to reduce misinterpretations and to raise the statistical significance of the procedure. Hence, the calibration of the parameters composing the model was run in a subsection, equal to 8% of the total length, randomly selected within the surveyed track. Finally, as validation, the model has been applied to the whole analysed dataset. As a result, the empirical model showed a good effectiveness in predicting the mechanical response of the pavement, with a normalised root mean squared deviation equal to 0.27. Finally, by averaging the measured and predicted mechanical data every 50 m and sorting the results into strength classes, a

  6. Large-bore pipe decontamination

    International Nuclear Information System (INIS)

    Ebadian, M.A.

    1998-01-01

    The decontamination and decommissioning (D and D) of 1200 buildings within the US Department of Energy-Office of Environmental Management (DOE-EM) Complex will require the disposition of miles of pipe. The disposition of large-bore pipe, in particular, presents difficulties in the area of decontamination and characterization. The pipe is potentially contaminated internally as well as externally. This situation requires a system capable of decontaminating and characterizing both the inside and outside of the pipe. Current decontamination and characterization systems are not designed for application to this geometry, making the direct disposal of piping systems necessary in many cases. The pipe often creates voids in the disposal cell, which requires the pipe to be cut in half or filled with a grout material. These methods are labor intensive and costly to perform on large volumes of pipe. Direct disposal does not take advantage of recycling, which could provide monetary dividends. To facilitate the decontamination and characterization of large-bore piping and thereby reduce the volume of piping required for disposal, a detailed analysis will be conducted to document the pipe remediation problem set; determine potential technologies to solve this remediation problem set; design and laboratory test potential decontamination and characterization technologies; fabricate a prototype system; provide a cost-benefit analysis of the proposed system; and transfer the technology to industry. This report summarizes the activities performed during fiscal year 1997 and describes the planned activities for fiscal year 1998. Accomplishments for FY97 include the development of the applicable and relevant and appropriate regulations, the screening of decontamination and characterization technologies, and the selection and initial design of the decontamination system

  7. Heat pipe and method of production of a heat pipe

    International Nuclear Information System (INIS)

    Kemp, R.S.

    1975-01-01

    The heat pipe consists of a copper pipe in which a capillary network or wick of heat-conducting material is arranged in direct contact with the pipe along its whole length. Furthermore, the interior space of the tube contains an evaporable liquid for pipe transfer. If water is used, the capillary network consists of, e.g., a phosphorus band network. To avoid contamination of the interior of the heat pipe during sealing, its ends are closed by mechanical deformation so that an arched or plane surface is obtained which is in direct contact with the network. After evacuation of the interior space, the remaining opening is closed with a tapered pin. The ratio wall thickness/tube diameter is between 0.01 and 0.6. (TK/AK) [de

  8. Obstructive sleep apnea and obesity are associated with reduced GPR 120 plasma levels in children.

    Science.gov (United States)

    Gozal, David; Kheirandish-Gozal, Leila; Carreras, Alba; Khalyfa, Abdelnaby; Peris, Eduard

    2014-05-01

    Obstructive sleep apnea (OSA) is a common health problem, particularly in obese children, in whom a vicious cycle of obesity and OSA interdependencies promotes increased food intake. G protein-coupled receptor 120 (GPR 120) is a long-chain free fatty acid (FFA) receptor that plays an important role in energy homeostasis, and protects against insulin resistance and systemic inflammation. We hypothesized that GPR 120 levels would be reduced in children with OSA, particularly among obese children. Cross-sectional prospectively recruited cohort. Academic pediatric sleep program. Two hundred twenty-six children (mean age: 7.0 ± 2.1 y) underwent overnight polysomnographic evaluation and a fasting blood draw the morning after the sleep study. In addition to lipid profile, homeostasis model assessment of insulin resistance (HOMA-IR) and high-sensitivity C-reactive protein (hsCRP) assays, monocyte GPR 120 expression, and plasma GPR 120 levels were assessed using quantitative polymerase chain reaction and enzyme-linked immunosorbent assay kits. Obese children and those with OSA had significantly lower GPR 120 monocyte expression and plasma GPR 120 levels. Furthermore, when both obesity and OSA were present, GPR 120 levels were lowest. Linear associations emerged between GPR 120 plasma levels and body mass index (BMI) z score, as well as with apnea-hypopnea index (AHI), saturation of peripheral oxygen (SpO2) nadir, and respiratory arousal index (RAI), with RAI remaining statistically significant when controlling for age, ethnicity, sex, and BMI z score (P GPR 120 levels, but neither low density lipoprotein nor high density lipoprotein cholesterol or hsCRP levels exhibited significant correlations. G protein-coupled receptor 120 (GPR 120) levels are reduced in pediatric OSA and obesity (particularly when both are present) and may play a role in modulating the degree of insulin resistance. The short- and long-term significance of reduced GPR 120 relative to food intake and

  9. Mice lacking Gpr37 exhibit decreased expression of the myelin-associated glycoprotein MAG and increased susceptibility to demyelination.

    Science.gov (United States)

    Smith, Brilee M; Giddens, Michelle M; Neil, Jessica; Owino, Sharon; Nguyen, TrangKimberly T; Duong, Duc; Li, Fengqiao; Hall, Randy A

    2017-09-01

    GPR37 is an orphan G protein-coupled receptor that is predominantly expressed in the brain and found at particularly high levels in oligodendrocytes. GPR37 has been shown to exert effects on oligodendrocyte differentiation and myelination during development, but the molecular basis of these actions is incompletely understood and moreover nothing is known about the potential role(s) of this receptor under demyelinating conditions. To shed light on the fundamental biology of GPR37, we performed proteomic studies comparing protein expression levels in the brains of mice lacking GPR37 and its close relative GPR37-like 1 (GPR37L1). These studies revealed that one of the proteins most sharply decreased in the brains of Gpr37/Gpr37L1 double knockout mice is the myelin-associated glycoprotein MAG. Follow-up Western blot studies confirmed this finding and demonstrated that genetic deletion of Gpr37, but not Gpr37L1, results in strikingly decreased brain expression of MAG. Further in vitro studies demonstrated that GPR37 and MAG form a complex when expressed together in cells. As loss of MAG has previously been shown to result in increased susceptibility to brain insults, we additionally assessed Gpr37-knockout (Gpr37 - / - ) vs. wild-type mice in the cuprizone model of demyelination. These studies revealed that Gpr37 - / - mice exhibit dramatically increased loss of myelin in response to cuprizone, yet do not show any increased loss of oligodendrocyte precursor cells or mature oligodendrocytes. These findings reveal that loss of GPR37 alters oligodendrocyte physiology and increases susceptibility to demyelination, indicating that GPR37 could be a potential drug target for the treatment of demyelinating diseases such as multiple sclerosis. Copyright © 2017 IBRO. Published by Elsevier Ltd. All rights reserved.

  10. GPR119 is required for physiological regulation of glucagon-like peptide-1 secretion but not for metabolic homeostasis.

    Science.gov (United States)

    Lan, Hong; Vassileva, Galya; Corona, Aaron; Liu, Li; Baker, Hana; Golovko, Andrei; Abbondanzo, Susan J; Hu, Weiwen; Yang, Shijun; Ning, Yun; Del Vecchio, Robert A; Poulet, Frederique; Laverty, Maureen; Gustafson, Eric L; Hedrick, Joseph A; Kowalski, Timothy J

    2009-05-01

    G protein-coupled receptor 119 (GPR119) is expressed in pancreatic islets and intestine, and is involved in insulin and incretin hormone release. GPR119-knockout (Gpr119(-/-)) mice were reported to have normal islet morphology and normal size, body weight (BW), and fed/fasted glucose levels. However, the physiological function of GPR119 and its role in maintaining glucose homeostasis under metabolic stress remain unknown. Here, we report the phenotypes of an independently generated line of Gpr119(-/-) mice under basal and high-fat diet (HFD)-induced obesity. Under low-fat diet feeding, Gpr119(-/-) mice show normal plasma glucose and lipids, but have lower BWs and lower post-prandial levels of active glucagon-like peptide 1 (GLP-1). Nutrient-stimulated GLP-1 release is attenuated in Gpr119(-/-) mice, suggesting that GPR119 plays a role in physiological regulation of GLP-1 secretion. Under HFD-feeding, both Gpr119(+)(/)(+) and Gpr119(-/-) mice gain weight similarly, develop hyperinsulinemia and hyperleptinemia, but not hyperglycemia or dyslipidemia. Glucose and insulin tolerance tests did not reveal a genotypic difference. These data show that GPR119 is not essential for the maintenance of glucose homeostasis. Moreover, we found that oleoylethanolamide (OEA), reported as a ligand for GPR119, was able to suppress food intake in both Gpr119(+)(/)(+) and Gpr119(-/-) mice, indicating that GPR119 is not required for the hypophagic effect of OEA. Our results demonstrate that GPR119 is important for incretin and insulin secretion, but not for appetite suppression.

  11. Mechanical Behaviour of Lined Pipe

    NARCIS (Netherlands)

    Hilberink, A.

    2011-01-01

    Installing lined pipe by means of the reeling installation method seems to be an attractive combination, because it provides the opportunity of eliminating the demanding welds from the critical time offshore and instead preparing them onshore. However, reeling of lined pipe is not yet proven

  12. The Interactions Between GPR30 and the Major Biomarkers in Infiltrating Ductal Carcinoma of the Breast in an Asian Population

    Directory of Open Access Journals (Sweden)

    Wen-Hung Kuo

    2007-06-01

    Conclusion: GPR30 expression is downregulated in IDC. GPR30 is preferentially co-expressed with ER and/or PR but is lowly expressed in HER-2/neu(+ tumors. The correlation of GPR30 expression with clinical parameters, including patient survival, was not evident in this cohort.

  13. Flexible ultrasonic pipe inspection apparatus

    Science.gov (United States)

    Jenkins, Charles F.; Howard, Boyd D.

    1998-01-01

    A flexible, modular ultrasonic pipe inspection apparatus, comprising a flexible, hollow shaft that carries a plurality of modules, including at least one rotatable ultrasonic transducer, a motor/gear unit, and a position/signal encoder. The modules are connected by flexible knuckle joints that allow each module of the apparatus to change its relative orientation with respect to a neighboring module, while the shaft protects electrical wiring from kinking or buckling while the apparatus moves around a tight corner. The apparatus is moved through a pipe by any suitable means, including a tether or drawstring attached to the nose or tail, differential hydraulic pressure, or a pipe pig. The rotational speed of the ultrasonic transducer and the forward velocity of the apparatus are coordinated so that the beam sweeps out the entire interior surface of the pipe, enabling the operator to accurately assess the condition of the pipe wall and determine whether or not leak-prone corrosion damage is present.

  14. Advanced GPR data processing algorithms for detection of anti-personnel landmines

    NARCIS (Netherlands)

    Kovalenko, V.

    2006-01-01

    Ground Penetrating Radar (GPR) is seen as one of several promising technologies aimed to help mine detection. GPR is sensitive to any inhomogeneity in the ground. Therefore any APM regardless of the metal content can be detected. On the other hand, all the inhomogeneities, which do not represent

  15. Ground penetrating radar (GPR) detects fine roots of agricultural crops in the field

    Science.gov (United States)

    Xiuwei Liu; Xuejun Dong; Qingwu Xue; Daniel I. Leskovar; John Jifon; John R. Butnor; Thomas Marek

    2018-01-01

    Aim Ground penetrating radar (GPR) as a non-invasive technique is widely used in coarse root detection. However, the applicability of the technique to detect fine roots of agricultural crops is unknown. The objective of this study was to assess the feasibility of utilizing GPR to detect fine roots in the field.

  16. Weighted near-field focusing in an array-based GPR

    NARCIS (Netherlands)

    Savelyev, T.G.; Yarovoy, A.G.; Ligthart, L.P.

    2008-01-01

    This paper presents a 3-D imaging technique for an ultra-wideband (UWB) ground penetrating radar (GPR) with a single transmit antenna and a linear receive array. The video impulse GPR working in the frequency band of 0.3–3 GHz has been designed in IRCTR for landmine detection, i.e., for a near-field

  17. The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat

    DEFF Research Database (Denmark)

    Schilperoort, Maaike; van Dam, Andrea D; Hoeke, Geerte

    2018-01-01

    Brown adipose tissue (BAT) activation stimulates energy expenditure in human adults, which makes it an attractive target to combat obesity and related disorders. Recent studies demonstrated a role for G protein-coupled receptor 120 (GPR120) in BAT thermogenesis. Here, we investigated the therapeu......Brown adipose tissue (BAT) activation stimulates energy expenditure in human adults, which makes it an attractive target to combat obesity and related disorders. Recent studies demonstrated a role for G protein-coupled receptor 120 (GPR120) in BAT thermogenesis. Here, we investigated...... the therapeutic potential of GPR120 agonism and addressed GPR120-mediated signaling in BAT We found that activation of GPR120 by the selective agonist TUG-891 acutely increases fat oxidation and reduces body weight and fat mass in C57Bl/6J mice. These effects coincided with decreased brown adipocyte lipid content...... and increased nutrient uptake by BAT, confirming increased BAT activity. Consistent with these observations, GPR120 deficiency reduced expression of genes involved in nutrient handling in BAT Stimulation of brown adipocytes in vitro with TUG-891 acutely induced O2 consumption, through GPR120-dependent and GPR...

  18. GPR56/ADGRG1 Inhibits Mesenchymal Differentiation and Radioresistance in Glioblastoma

    NARCIS (Netherlands)

    Moreno, Marta; Pedrosa, Leire; Pare, Laia; Pineda, Estela; Bejarano, Leire; Martinez, Josefina; Balasubramaniyan, Veerakumar; Ezhilarasan, Ravesanker; Kallarackal, Naveen; Kim, Sung-Hak; Wang, Jia; Audia, Alessandra; Conroy, Siobhan; Marin, Mercedes; Ribalta, Teresa; Pujol, Teresa; Herreros, Antoni; Tortosa, Avelina; Mira, Helena; Alonso, Marta M.; Gomez-Manzano, Candelaria; Graus, Francesc; Sulman, Erik P.; Piao, Xianhua; Nakano, Ichiro; Prat, Aleix; Bhat, Krishna P.; de la Iglesia, Nuria

    2017-01-01

    A mesenchymal transition occurs both during the natural evolution of glioblastoma (GBM) and in response to therapy. Here, we report that the adhesion G-protein-coupled receptor, GPR56/ADGRG1, inhibits GBM mesenchymal differentiation and radioresistance. GPR56 is enriched in proneural and

  19. GPR Detection of Buried Symmetrically Shaped Mine-like Objects using Selective Independent Component Analysis

    DEFF Research Database (Denmark)

    Karlsen, Brian; Sørensen, Helge Bjarup Dissing; Larsen, Jan

    2003-01-01

    from small-scale anti-personal (AP) mines to large-scale anti-tank (AT) mines were designed. Large-scale SF-GPR measurements on this series of mine-like objects buried in soil were performed. The SF-GPR data was acquired using a wideband monostatic bow-tie antenna operating in the frequency range 750...

  20. GPR39 Zn2+-sensing receptor

    DEFF Research Database (Denmark)

    Młyniec, Katarzyna; Singewald, Nicolas; Holst, Birgitte

    2015-01-01

    ). Preclinical studies provide evidence that zinc deficiency leads to depressive-like behavior related to down-regulation of the GPR39 Zn2+-sensing receptor. Zinc binds to the GPR39 and triggers signals, leading to CRE-dependent gene transcription, resulting in increases in proteins such as brain...

  1. Association study in three different populations between the GPR88 gene and major psychoses

    Science.gov (United States)

    Del Zompo, Maria; Deleuze, Jean-François; Chillotti, Caterina; Cousin, Emmanuelle; Niehaus, Dana; Ebstein, Richard P; Ardau, Raffaella; Macé, Sandrine; Warnich, Louise; Mujahed, Mustafa; Severino, Giovanni; Dib, Colette; Jordaan, Esme; Murad, Ibrahim; Soubigou, Stéphane; Koen, Liezl; Bannoura, Issam; Rocher, Corinne; Laurent, Claudine; Derock, Murielle; Faucon Biguet, Nicole; Mallet, Jacques; Meloni, Rolando

    2014-01-01

    GPR88, coding for a G protein-coupled orphan receptor that is highly represented in the striatum, is a strong functional candidate gene for neuropsychiatric disorders and is located at 1p22-p21, a chromosomal region that we have previously linked to bipolar disorder (BD) in the Sardinian population. In order to ascertain the relevance of GPR88 as a risk factor for psychiatric diseases, we performed a genetic association analysis between GPR88 and BD in a sample of triads (patient and both parents) recruited in the Sardinian and the Palestinian population as well as between GPR88 and schizophrenia (SZ) in triads from the Xhosa population in South Africa. We found a positive association between GPR88 and BD in the Sardinian and Palestinian triads. Moreover, we found a positive association between GPR88 and SZ in triads from the Xhosa population in South Africa. When these results were corrected for multiple testing, the association between GPR88 and BD was maintained in the Palestinian population. Thus, these results suggest that GPR88 deserves consideration as a candidate gene for psychiatric diseases and requires to be further investigated in other populations. PMID:24689078

  2. Tomographic site characterization using CPT, ERT, and GPR. Innovative Technology Summary Report

    International Nuclear Information System (INIS)

    None

    2000-01-01

    ARA developed a geophysical tomographic system that incorporates results from Electrical Resistivity Tomography (ERT) measurements and Ground Penetrating Radar (GPR) Tomography measurements. Both methods are useful for imaging subsurface structures and processes, however, GPR is more effective in sandy material and ERT is more effective in clayey material. CPT or drilling is used to deploy the electrodes in the subsurface

  3. Identification of GPR65, a novel regulator of matrix metalloproteinases using high through-put screening

    International Nuclear Information System (INIS)

    Xu, Hongbo; Chen, Xiaohong; Huang, Junwei; Deng, Weiwei; Zhong, Qi; Yue, Changli; Wang, Pingzhang; Huang, Zhigang

    2013-01-01

    Highlights: •A novel mechanism of MMP3 regulation by proton-sensing G-protein-coupled receptors was defined. •GPR65 was identified to induce the MMP3 expression. •GPR65 mediated MMP induction under acidic conditions. •AP-1 binding site in MMP3 promoter was crucial for MMP3 induction. •GPR65 overexpression can accelerate the invision of A549 cells. -- Abstract: Matrix metalloproteinases (MMPs) are over-expressed in nearly all cancers. To study novel regulatory factors of MMP expression in head and neck cancer (HNC), we screened a total of 636 candidate genes encoding putative human transmembrane proteins using MMP promoter reporter in a dual luciferase assay system. Three genes GPR65, AXL and TNFRSF10B dramatically activated the induction of MMP3 expression. The induction of MMP expression by GPR65 was further confirmed in A549 and/or FaDu cells. GPR65 mediated MMP induction under acidic conditions. The AP-1 binding site in MMP3 promoter was crucial for MMP3 induction. Moreover, the A549 cells infected by recombinant adenovirus of GPR65 showed accelerated cell invasion. In conclusion, we validate that GPR65 is vital regulatory genes upstream of MMP3, and define a novel mechanism of MMP3 regulation by proton-sensing G-protein-coupled receptors

  4. Linear GPR Imaging Based on Electromagnetic Plane-Wave Spectra and Diffraction Tomography

    DEFF Research Database (Denmark)

    Meincke, Peter

    2004-01-01

    in the forward model. The two inversion schemes include an accurate electromagnetic description of the GPR antennas through their plane-wave transmitting and receiving spectra. The performance of the FTM is investigated through a numerical example involving a 2.5-dimensional configuration in which the GPR...

  5. Evidence for a role of KISS-1/GPR54 system in decreased ...

    African Journals Online (AJOL)

    Short fasting has been shown to suppress luteinizing hormone (LH) secretion in ewes, however, the molecular mechanism underlying this phenomenon is not clear. Based on recent discovery of the crucial role of KiSS-1/GPR54 system in the central control of the GnRH axis, we hypothesized that KiSS-1/GPR54 system was ...

  6. Identification of GPR65, a novel regulator of matrix metalloproteinases using high through-put screening

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Hongbo; Chen, Xiaohong; Huang, Junwei [Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Beijing (China); Deng, Weiwei [Functional Genomics Group, Chinese National Human Genome Center (CHGB) at Beijing (China); Zhong, Qi [Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Beijing (China); Yue, Changli [Department of Pathology, Beijing Tongren Hospital, Capital Medical University, Beijing (China); Wang, Pingzhang, E-mail: wangpzh@bjmu.edu.cn [Department of Immunology, School of Basic Medical Sciences, Peking University Health Science Center, Peking University Center for Human Disease Genomics, Key Laboratory of Medical Immunology, Ministry of Health (China); Functional Genomics Group, Chinese National Human Genome Center (CHGB) at Beijing (China); Huang, Zhigang, E-mail: enthuangzhigang@sohu.com [Department of Otolaryngology-Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Beijing (China)

    2013-06-21

    Highlights: •A novel mechanism of MMP3 regulation by proton-sensing G-protein-coupled receptors was defined. •GPR65 was identified to induce the MMP3 expression. •GPR65 mediated MMP induction under acidic conditions. •AP-1 binding site in MMP3 promoter was crucial for MMP3 induction. •GPR65 overexpression can accelerate the invision of A549 cells. -- Abstract: Matrix metalloproteinases (MMPs) are over-expressed in nearly all cancers. To study novel regulatory factors of MMP expression in head and neck cancer (HNC), we screened a total of 636 candidate genes encoding putative human transmembrane proteins using MMP promoter reporter in a dual luciferase assay system. Three genes GPR65, AXL and TNFRSF10B dramatically activated the induction of MMP3 expression. The induction of MMP expression by GPR65 was further confirmed in A549 and/or FaDu cells. GPR65 mediated MMP induction under acidic conditions. The AP-1 binding site in MMP3 promoter was crucial for MMP3 induction. Moreover, the A549 cells infected by recombinant adenovirus of GPR65 showed accelerated cell invasion. In conclusion, we validate that GPR65 is vital regulatory genes upstream of MMP3, and define a novel mechanism of MMP3 regulation by proton-sensing G-protein-coupled receptors.

  7. CAPACITIVE TOMOGRAPHY FOR THE LOCATION OF PLASTIC PIPE

    Energy Technology Data Exchange (ETDEWEB)

    Brian J. Huber

    2003-12-30

    The objective of this program was to develop and test a system that would detect and image buried plastic and ceramic pipe. The system is designed to detect variations in the electric permeability of soil corresponding to the presence of a buried plastic pipe. The Gas Technology Institute (GTI) proposed to develop a compact and inexpensive capacitive tomography-imaging sensor that can be placed on the ground to image objects embedded in the soil. The system provides a coarse image, which allows the operator to identify a buried object's location both horizontally and vertically.

  8. Device for overlapping of a column of pump compressor pipes

    Energy Technology Data Exchange (ETDEWEB)

    Sharafutdinov, I.G.; Akhmerov, M.N.; Asadullin, Kh.F.; Prokopov, O.I.

    1980-02-16

    A device is proposed for automatic overlapping of pump compressor pipes of gushing petroleum and gas wells when losses occur near the well. The objective of the invention is to increase efficiency of the overlapping of the pipe column by recharging the device directly at the hole without disassembling the head equipment. This objective is achieved as follows. The device is equipped with elastic spacers located in the channels of a ring. They are mounted with the possibility of interaction with ball catches. A drawing and description of the device are given.

  9. Test site experiments with a reconfigurable stepped frequency GPR

    Science.gov (United States)

    Persico, Raffaele; Matera, Loredana; Piro, Salvatore; Rizzo, Enzo; Capozzoli, Luigi

    2016-04-01

    In this contribution, some new possibilities offered by a reconfigurable stepped frequency GPR system are exposed. In particular, results achieved from a prototypal system achieved in two scientific test sites will be shown together with the results achieved in the same test sites with traditional systems. Moreover a novel technique for the rejection of undesired interferences is shown, with the use of interferences caused on purpose. Key words GPR, reconfigurable stepped frequency. Introduction A reconfigurable GPR system is meant as a GPR where some parameter can be changed vs. the frequency (if the system is stepped frequency) or vs. the time (if the system is pulsed) in a programmable way. The programming should then account for the conditions met in the scenario at hand [1]. Within the research project AITECH (http://www.aitechnet.com/ibam.html), the Institute for Archaeological and Monumental Heritage, together with the University of Florence and the IDS corporation have implemented a prototype, that has been used in sites of cultural interest in Italy [2], but also abroad in Norway and Malta. The system is a stepped frequency GPR working in the frequency range 50-1000 MHz, and its reconfigurability consists in three properties. The first one is the fact that the length of the antennas can be modulated by the aperture and closure of two electronic switches present along the arms of the antennas, so that the antennas can become electrically (and electronically) longer or shorter, so becoming more suitable to radiate some frequencies rather than some other. In particular, the system can radiate three different bands in the comprehensive range between 50-1000 MHz, so being suitable for different depth range of the buried targets, and the three bands are gathered in a unique "going through" because for each measurement point the system can sweep the entire frequency range trhee times, one for each configuration of the switchres on the arms. The second property is

  10. Magnetic and GPR surveys of a former munitions foundry site at the Denver Federal Center

    Science.gov (United States)

    Campbell, David L.; Beanland, Shay; Lucius, Jeffrey E.; Powers, Michael H.

    2000-01-01

    We made magnetometer and ground penetrating radar (GPR) surveys over part of the foundation of a World War II-era foundry located on the Denver Federal Center. The site contains a number of highly magnetic source bodies, concrete foundation walls, and underground openings, buried under a clay cap. The cap is several feet thick and has a conductivity of about 35 mS/m, making the features underneath it a poor target for conventional GPR. Indeed, the raw data look unlike typical GPR data, but rather show reverberation (?) bands under sidewalks and other shallow buried sources. Using a newly-written computer package, we made plan maps of the GPR response at different time slices. The sliced GPR data did not outline buried foundry foundations, as we had hoped it might. The resulting plan maps of the sliced data show sidewalks and other blobby features, some of which correspond to magnetometer highs.

  11. Signal processing technology and its application research of ground penetrating radar (GPR)

    Science.gov (United States)

    Wang, Wanshun; Hao, Lisheng; Li, Xiuwen; Sun, Jianhui

    2017-06-01

    Ground Penetrating Radar(GPR) technology is a kind of rapid and continuous detection method with high precision and intuitive image. It is an electromagnetic wave technology used to determine the distribution of the underground media spectrum (1 MHZ - 3 GHZ). The applications of GPR is facing the influence of various interference in various complex environments and the main direction of GPR application research is how to remove interference and how to extract the useful information. The signal processing Is means of the radar to implement the signal retrieval and information extraction. Based on the analysis of the signal processing technology of GPR used commonly, the paper applies these methods to the processing and interpretation of GPR data in an engineering example and illustrates the purpose and the treatment manner of the various signal processing technology.

  12. Use of GPR Surveys in Historical Archaeology Studies at Gainesville Mississippi

    Science.gov (United States)

    Goodwin, Ben; Giardino, Marco; Spruce, Joe

    2002-01-01

    Ground Penetrating Radar (GPR) was used in recent surveys to acquire subsurface geophysical data for historic sites at Gainesville, Mississippi, a town abandoned in 1962 with the building of the John C. Stennis Space Center. Prior to GPR data collection, a 20- by 20-meter grid was established using UTM map projection and GPS for locating cell corners. Lines of GPR data were then collected every 25 centimeters. The images were then processed, and coregistered to georeferenced aerial and satellite imagery. This procedure is enabling analysts to assess the GPR imagery more effectively in a geospatial context. Field validation of anomalies created by known subsurface features from both recent and historic sources is allowing soil attributes, such as variations in Relative Dielectric Permittivity, to be tested more accurately. Additional work is assessing how GPR data can be effectively combined with other forms of remote sensing to direct archaeological surveys and excavations.

  13. Rod photoreceptors express GPR55 in the adult vervet monkey retina

    DEFF Research Database (Denmark)

    Bouskila, Joseph; Javadi, Pasha; Casanova, Christian

    2013-01-01

    . Yet, its formal classification is still a matter of debate. CB1R and CB2R expression patterns are well described for rodent and monkey retinas. In the monkey retina, CB1R has been localized in its neural (cone photoreceptor, horizontal, bipolar, amacrine and ganglion cells) and CB2R in glial...... components (Müller cells). The aim of this study was to determine the expression pattern of GPR55 in the monkey retina by using confocal microscopy. Our results show that GPR55 is strictly localized in the photoreceptor layer of the extrafoveal portion of the retina. Co-immunolabeling of GPR55 with rhodopsin......, the photosensitive pigment in rods, revealed a clear overlap of expression throughout the rod structure with most prominent staining in the inner segments. Additionally, double-label of GPR55 with calbindin, a specific marker for cone photoreceptors in the primate retina, allowed us to exclude expression of GPR55...

  14. Expression and localization of the omega-3 fatty acid receptor GPR120 in human term placenta

    Science.gov (United States)

    Lager, Susanne; Ramirez, Vanessa I.; Gaccioli, Francesca; Jansson, Thomas; Powell, Theresa L.

    2014-01-01

    Fatty acids can function as signaling molecules, acting through receptors in the cytosol or on the cell surface. G-Protein Receptor (GPR)120 is a membrane-bound receptor mediating anti-inflammatory and insulin-sensitizing effects of the omega-3 fatty acid docohexaenoic acid (DHA). GPR120 dysfunction is associated with obesity in humans. Cellular localization of GPR120 and the influence of maternal obesity on GPR120 protein expression in the placenta are unknown. Herein we demonstrate that GPR120 is predominantly expressed in the microvillous membrane (MVM) of human placenta and that the expression level of this receptor in MVM is not altered by maternal body mass index (BMI). PMID:24844436

  15. GPR39 is coupled to TMEM16A in intestinal fibroblast-like cells.

    Directory of Open Access Journals (Sweden)

    Fanning Zeng

    Full Text Available GPR39 is a GPCR implicated as a regulator of gastrointestinal motility, although the mechanism remains elusive. Here, we report that GPR39 is expressed by a specific cell population cultured from mouse small intestine muscle layers, which was subsequently identified as fibroblast-like cells (FLCs that have recently been shown to modulate gut motility. Application of the GPR39 agonist, Zn(2+, induced large currents and membrane depolarization in FLCs cultured from wild-type mice, but not Gpr39(-/- mice. This Zn(2+-induced current could be suppressed by application of a TMEM16A antagonist, CaCC(inh-A01, or by silencing Tmem16a expression. These data suggest that GPR39 might modulate gut motility via regulating TMEM16A function in FLCs.

  16. GPR39 signaling is stimulated by zinc ions but not by obestatin

    DEFF Research Database (Denmark)

    Holst, Birgitte; Egerod, Kristoffer L; Schild, Enrico

    2006-01-01

    organs such as duodenum and kidney but not in the pituitary and hypothalamus, i.e. presumed central target organs for obestatin. Obestatin had no significant and reproducible effect on acute food intake in either freely fed or fasted lean mice. It is concluded that GPR39 is probably not the obestatin......GPR39 is an orphan member of the ghrelin receptor family that recently was suggested to be the receptor for obestatin, a peptide derived from the ghrelin precursor. Here, we compare the effect of obestatin to the effect of Zn(2+) on signal transduction and study the effect of obestatin on food...... was obtained with obestatin in the GPR39-expressing cells. Moreover, no specific binding of obestatin could be detected in two different types of GPR39-expressing cells using three different radioiodinated forms of obestatin. By quantitative PCR analysis, GPR39 expression was readily detected in peripheral...

  17. Overexpressing cell systems are a competitive option to primary adipocytes when predicting in vivo potency of dual GPR81/GPR109A agonists.

    Science.gov (United States)

    Almquist, Joachim; Hovdal, Daniel; Ahlström, Christine; Fjellström, Ola; Gennemark, Peter; Sundqvist, Monika

    2018-03-01

    Mathematical models predicting in vivo pharmacodynamic effects from in vitro data can accelerate drug discovery, and reduce costs and animal use. However, data integration and modeling is non-trivial when more than one drug-target receptor is involved in the biological response. We modeled the inhibition of non-esterified fatty acid release by dual G-protein-coupled receptor 81/109A (GPR81/GPR109A) agonists in vivo in the rat, to estimate the in vivo EC 50 values for 12 different compounds. We subsequently predicted those potency estimates using EC 50 values obtained from concentration-response data in isolated primary adipocytes and cell systems overexpressing GPR81 or GPR109A in vitro. A simple linear regression model based on data from primary adipocytes predicted the in vivo EC 50 better than simple linear regression models based on in vitro data from either of the cell systems. Three models combining the data from the overexpressing cell systems were also evaluated: two piecewise linear models defining logical OR- and AND-circuits, and a multivariate linear regression model. All three models performed better than the simple linear regression model based on data from primary adipocytes. The OR-model was favored since it is likely that activation of either GPR81 or GPR109A is sufficient to deactivate the cAMP pathway, and thereby inhibit non-esterified fatty acid release. The OR-model was also able to predict the in vivo selectivity between the two receptors. Finally, the OR-model was used to predict the in vivo potency of 1651 new compounds. This work suggests that data from the overexpressing cell systems are sufficient to predict in vivo potency of GPR81/GPR109A agonists, an approach contributing to faster and leaner drug discovery. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Influence of pipe material and surfaces on sulfide related odor and corrosion in sewers.

    Science.gov (United States)

    Nielsen, Asbjørn Haaning; Vollertsen, Jes; Jensen, Henriette Stokbro; Wium-Andersen, Tove; Hvitved-Jacobsen, Thorkild

    2008-09-01

    Hydrogen sulfide oxidation on sewer pipe surfaces was investigated in a pilot scale experimental setup. The experiments were aimed at replicating conditions in a gravity sewer located immediately downstream of a force main where sulfide related concrete corrosion and odor is often observed. During the experiments, hydrogen sulfide gas was injected intermittently into the headspace of partially filled concrete and plastic (PVC and HDPE) sewer pipes in concentrations of approximately 1,000 ppm(v). Between each injection, the hydrogen sulfide concentration was monitored while it decreased because of adsorption and subsequent oxidation on the pipe surfaces. The experiments showed that the rate of hydrogen sulfide oxidation was approximately two orders of magnitude faster on the concrete pipe surfaces than on the plastic pipe surfaces. Removal of the layer of reaction (corrosion) products from the concrete pipes was found to reduce the rate of hydrogen sulfide oxidation significantly. However, the rate of sulfide oxidation was restored to its background level within 10-20 days. A similar treatment had no observable effect on hydrogen sulfide removal in the plastic pipe reactors. The experimental results were used to model hydrogen sulfide oxidation under field conditions. This showed that the gas-phase hydrogen sulfide concentration in concrete sewers would typically amount to a few percent of the equilibrium concentration calculated from Henry's law. In the plastic pipe sewers, significantly higher concentrations were predicted because of the slower adsorption and oxidation kinetics on such surfaces.

  19. Improvement of the energetic properties of the GPR

    Science.gov (United States)

    Pochanin, Gennadiy P.; Ruban, Vadim P.; Kholod, Pavlo V.; Shuba, Alexander A.; Pochanin, Alexander G.; Orlenko, Alexander A.

    2014-05-01

    The necessary condition for the expansion of the impulse Ground Penetrating Radar (GPR) applications is to improve the GPR energy performance for the detection of signals on the background of noise. Digital signal processing techniques allow suppressing the noise largely, but they work only when the GPR is able to register the reflected signals. The majority of the modern GPRs use sampling receivers. They allow recording signals of a very short du- ration. However, very large energy losses are inherent to this method. To improve the signal to noise ratio it is possible to increase the power of the probing signal and to de- crease the noise level of the receiver. In GPR, the transmitting and receiving antennas are usually electrodynamically coupled because they are situated quite close to each other. The sensitive input circuit of the receiver does not allow the excess of the signal amplitude typically more than 1 V. Thus, the increase of the intensity of the probing signal is possible only up to a certain level. To overcome this limitation, it was proposed to design an antenna in such a way that the coupling between the transmitting and receiving sections was absent or minimal. A special method that provided the decoupling below -64 dB was invented (theoretically the isolation is absolute and frequency independent). In order to register as short as possible signals, researchers strive to make sample duration of the sampling converter as short as possible. However, the shorter the sample duration, the smaller the energy of the signal that can be received and the larger the noise. Due to the dispersive absorption of electromagnetic waves in the ground, the high-frequency part of the signal spectrum is attenuated faster than the low-frequency part. It makes no sense to expect the arrival of very short pulses from deep reflectors. Thus, it is possible to increase the duration of the samples at reception of the signals from the deep objects. The authors proposed to

  20. Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression.

    Directory of Open Access Journals (Sweden)

    Nitin Patel

    Full Text Available Prostate cancer (PCa is the second-leading cause of cancer-related mortality, after lung cancer, in men from developed countries. In its early stages, primary tumor growth is dependent on androgens, thus generally can be controlled by androgen deprivation therapy (ADT. Eventually however, the disease progresses to castration-resistant prostate cancer (CRPC, a lethal form in need of more effective treatments. G-protein coupled receptors (GPCRs comprise a large clan of cell surface proteins that have been implicated as therapeutic targets in PCa growth and progression. The findings reported here provide intriguing evidence of a role for the newly characterized glutamate family member GPR158 in PCa growth and progression. We found that GPR158 promotes PCa cell proliferation independent of androgen receptor (AR functionality and that this requires its localization in the nucleus of the cell. This suggests that GPR158 acts by mechanisms different from other GPCRs. GPR158 expression is stimulated by androgens and GPR158 stimulates AR expression, implying a potential to sensitize tumors to low androgen conditions during ADT via a positive feedback loop. Further, we found GPR158 expression correlates with a neuroendocrine (NE differentiation phenotype and promotes anchorage-independent colony formation implying a role for GPR158 in therapeutic progression and tumor formation. GPR158 expression was increased at the invading front of prostate tumors that formed in the genetically defined conditional Pten knockout mouse model, and co-localized with elevated AR expression in the cell nucleus. Kaplan-Meier analysis on a dataset from the Memorial Sloan Kettering cancer genome portal showed that increased GPR158 expression in tumors is associated with lower disease-free survival. Our findings strongly suggest that pharmaceuticals targeting GPR158 activities could represent a novel and innovative approach to the prevention and management of CRPC.

  1. Waste pipe calculus extensions

    International Nuclear Information System (INIS)

    O'Connell, W.J.

    1979-01-01

    The waste pipe calculus provides a rapid method, using Laplace transforms, to calculate the transport of a pollutant such as nuclear waste, by a network of one-dimensional flow paths. The present note extends previous work as follows: (1) It provides an alternate approximation to the time-domain function (inverse Laplace transform) for the resulting transport. This algebraic approximation may be viewed as a simpler and more approximate model of the transport process. (2) It identifies two scalar quantities which may be used as summary consequence measures of the waste transport (or inversely, waste retention) system, and provides algebraic expressions for them. (3) It includes the effects of radioactive decay on the scalar quantity results, and further provides simplifying approximations for the cases of medium and long half-lives. This algebraic method can be used for quick approximate analyses of expected results, uncertainty and sensitivity, in evaluating selection and design choices for nuclear waste disposal systems

  2. Solar chemical heat pipe

    International Nuclear Information System (INIS)

    Levy, M.; Levitan, R.; Rosin, H.; Rubin, R.

    1991-08-01

    The performance of a solar chemical heat pipe was studied using CO 2 reforming of methane as a vehicle for storage and transport of solar energy. The endothermic reforming reaction was carried out in an Inconel reactor, packed with a Rh catalyst. The reactor was suspended in an insulated box receiver which was placed in the focal plane of the Schaeffer Solar Furnace of the Weizman Institute of Science. The exothermic methanation reaction was run in a 6-stage adiabatic reactor filled with the same Rh catalyst. Conversions of over 80% were achieved for both reactions. In the closed loop mode the products from the reformer and from the metanator were compressed into separate storage tanks. The two reactions were run either separately or 'on-line'. The complete process was repeated for over 60 cycles. The overall performance of the closed loop was quite satisfactory and scale-up work is in progress in the Solar Tower. (authors). 35 refs., 2 figs

  3. SEALING LARGE-DIAMETER CAST-IRON PIPE JOINTS UNDER LIVE CONDITIONS

    Energy Technology Data Exchange (ETDEWEB)

    Kiran M. Kothari; Gerard T. Pittard

    2005-07-01

    Utilities in the U.S. operate over 75,000 km (47,000 miles) of old cast-iron pipes for gas distribution. Bell-and-spigot joints that connect pipe sections together tend to leak as these pipes age. Current repair practices are costly and highly disruptive. The objective of this program is to design, test and commercialize a robotic system capable of sealing multiple castiron bell and spigot joints from a single pipe entry point. The proposed system will perform repairs with the pipe in service by traveling through the pipe, cleaning each joint surface, and installing a stainless-steel sleeve lined with an epoxy-impregnated felt across the joint. This approach will save considerable time and labor, minimize excavation, avoid traffic disruption, and eliminate any requirement to interrupt service to customers (which would result in enormous expense to utilities). Technical challenges include: (1) repair sleeves must compensate for diametric variation and eccentricity of old cast-iron pipes; (2) the assembly must travel long distances through pipes containing debris; (3) the pipe wall must be effectively cleaned in the immediate area of the joint to assure good bonding of the sleeve; and (4) an innovative bolt-on entry fitting is required to conduct safe repair operations on live mains.

  4. Monostatic ultra-wideband GPR antenna for through wall detection

    Directory of Open Access Journals (Sweden)

    Ali Jawad

    2017-01-01

    Full Text Available The aim of this paper is to present a monostatic arc-shaped ultra-wideband (UWB printed monopole antenna system with 3-16 GHz frequency bandwidth suitable for through-wall detection. Ground penetrating radar (GPR technique is used for detection with the gain of 6.2 dB achieved for the proposed antenna using defected ground structure (DGS method. To serve the purpose, a simulation experiment of through-wall detection model is constructed which consists of a monostatic antenna act as transmitter and receiver, concrete wall and human skin model. The time domain reflection of obtained result is then analysed for target detection.

  5. Inverse scattering and GPR data processing: an Introduction

    Science.gov (United States)

    Persico, Raffaele

    2014-05-01

    Inverse scattering and GPR data processing: an Introduction Raffaele Persico This abstract is meant to propose a brief overview of the book "Introduction to Ground Penetrating Radar: Inverse scattering and data processing", edited by Wiley Press (ISBN 9781118305003). The reason why I propose this contribution is the fact that, in spite of the large relevant literature, to the best of my knowledge it is not very common to find a text entirely devoted to the physical-mathematical aspects (a part of them, of course) of GPR data processing. Also due to this, probably a sort of gap between the GPR practice and the underlying theory has been created, and indeed we can meet practitioners convinced that the quality of the achieved results is indefinitely improvable by making narrower the spatial step of the data, or that it is desirable to have extremely directive antennas because this would improve the resolution. In order to provide a work hopefully able to address these and other aspects and hopefully able to give a contribution to the correction of these imprecise beliefs, a dealing from the beginning has been proposed, i.e. a sequential, relatively plane, and as much as possible self consistent, dealing starting from the Maxwell's equations and reaching the most commonly exploited migration formulas and linear inversion algorithms, both within a 2D and a 3D framework. This follows the didactic aim to provide to the reader an insight about what can be reasonably achieved and what should be reasonably done in the field and during the processing phase in order to achieve satisfying results. In particular, the reader will be hopefully made aware not only of the mathematical passages, but also of the involved approximations, the needed assumptions and the physical limits of the final algorithms. The results have been also back-upped with numerical exercises and with some experimental tests, all of which conceived on purpose for this text, and some questions with the

  6. Monostatic ultra-wideband GPR antenna for through wall detection

    Science.gov (United States)

    Ali, Jawad; Abdullah, Noorsaliza; Yahya, Roshayati; Naeem, Taimoor

    2017-11-01

    The aim of this paper is to present a monostatic arc-shaped ultra-wideband (UWB) printed monopole antenna system with 3-16 GHz frequency bandwidth suitable for through-wall detection. Ground penetrating radar (GPR) technique is used for detection with the gain of 6.2 dB achieved for the proposed antenna using defected ground structure (DGS) method. To serve the purpose, a simulation experiment of through-wall detection model is constructed which consists of a monostatic antenna act as transmitter and receiver, concrete wall and human skin model. The time domain reflection of obtained result is then analysed for target detection.

  7. GPR Technologies and Methodologies in Italy: A Review

    Science.gov (United States)

    Benedetto, Andrea; Frezza, Fabrizio; Manacorda, Guido; Massa, Andrea; Pajewski, Lara

    2014-05-01

    GPR techniques and technologies have been subject of intense research activities at the Italian level in the last 15 years because of their potential applications specifically to civil engineering. More in detail, several innovative approaches and models have been developed to inspect road pavements to measure the thickness of their layers as well as to diagnose or prevent damage. Moreover, new frontiers in bridge inspection as well as in geotechnical applications such as slides and flows have been investigated using GPR. From the methodological viewpoint, innovative techniques have been developed to solve GPR forward-scattering problems, as well to locate and classify subsurface targets in real-time and to retrieve their properties through multi-resolution strategies, and linear and non-linear methodologies. Furthermore, the application of GPR and other non-destructive testing methods in archaeological prospecting, cultural heritage diagnostics, and in the localization and detection of vital signs of trapped people has been widely investigated. More recently, new theoretical and empirical paradigms regarding water moisture evaluation in various porous media and soil characterization have been published as the results of long terms research activities. Pioneer studies are also currently under development with the scope to correlate GPR measurement with mechanical characteristics of bound and unbound construction materials. In such a framework, this abstract will be aimed at reviewing some of the most recent advances of GPR techniques and technologies within the Italian industrial and academic communities [also including their application within international projects such as FP7 ISTIMES (http://www.istimes.eu)], and at envisaging some of the most promising research trends currently under development. Acknowledgment - This work was supported by COST Action TU1208 'Civil Engineering Applications of Ground Penetrating Radar' References [1] M. Balsi, S. Esposito, F

  8. Decontamination and decommissioning of small-bore pipe

    International Nuclear Information System (INIS)

    Hackmann, E.K.

    1996-01-01

    The ability to aggressively decontaminate to U.S. Nuclear Regulatory Commission (NRC) free-release limits, verify the effectiveness, and prove releasability of contaminated piping systems are tasks that became a major concern for Westinghouse during the Fort St. Vrain (FSV) decommissioning project. The problem is especially acute for small-bore piping systems [2.5- to 7.6-cm (1- to 3-in.) diameter] with multiple elbows. Westinghouse, and its wholly owned subsidiary, Scientific Ecology Group, being one of the two primary contractors for decommissioning the FSV nuclear generating station [330-MW(electric) high-temperature gas-cooled reactor, operated from 1979 to 1989], encountered this problem and developed equipment and methodologies to successfully decontaminate, survey, and decommission this piping

  9. Mathematical models for two-phase stratified pipe flow

    Energy Technology Data Exchange (ETDEWEB)

    Biberg, Dag

    2005-06-01

    The simultaneous transport of oil, gas and water in a single multiphase flow pipe line has for economical and practical reasons become common practice in the gas and oil fields operated by the oil industry. The optimal design and safe operation of these pipe lines require reliable estimates of liquid inventory, pressure drop and flow regime. Computer simulations of multiphase pipe flow have thus become an important design tool for field developments. Computer simulations yielding on-line monitoring and look ahead predictions are invaluable in day-to-day field management. Inaccurate predictions may have large consequences. The accuracy and reliability of multiphase pipe flow models are thus important issues. Simulating events in large pipelines or pipeline systems is relatively computer intensive. Pipe-lines carrying e.g. gas and liquefied gas (condensate) may cover distances of several hundred km in which transient phenomena may go on for months. The evaluation times associated with contemporary 3-D CFD models are thus not compatible with field applications. Multiphase flow lines are therefore normally simulated using specially dedicated 1-D models. The closure relations of multiphase pipe flow models are mainly based on lab data. The maximum pipe inner diameter, pressure and temperature in a multiphase pipe flow lab is limited to approximately 0.3 m, 90 bar and 60{sup o}C respectively. The corresponding field values are, however, much higher i.e.: 1 m, 1000 bar and 200{sup o}C respectively. Lab data does thus not cover the actual field conditions. Field predictions are consequently frequently based on model extrapolation. Applying field data or establishing more advanced labs will not solve this problem. It is in fact not practically possible to acquire sufficient data to cover all aspects of multiphase pipe flow. The parameter range involved is simply too large. Liquid levels and pressure drop in three-phase flow are e.g. determined by 13 dimensionless parameters

  10. The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site

    DEFF Research Database (Denmark)

    Shehata, Mohamed A.; Jensen, Anne Cathrine Nøhr; Jespers, Willem

    2017-01-01

    for GPR139. Two series published by Shi et al. and Dvorak et al. included agonists 1a and 7c respectively, with potencies in the ten-nanomolar range. Furthermore, Isberg et al. and Liu et al. have previously shown that tryptophan (Trp) and phenylalanine (Phe) can activate GPR139 in the hundred...... important for the activation of GPR139 as predicted by the receptor model. The initial ligand-receptor complex was optimized through free energy perturbation simulations, generating a refined GPR139 model in agreement with experimental data. In summary, the GPR139 reference surrogate agonists 1a and 7c...

  11. PIV measurement at the blowdown pipe outlet

    International Nuclear Information System (INIS)

    Puustinen, M.; Laine, J.; Raesaenen, A.; Pyy, L.; Telkkae, J.

    2013-04-01

    This report summarizes the findings of the PIV measurement tests carried out in January - February 2013 with the scaled down PPOOLEX test facility at LUT. The main objective of the tests was to find out the operational limits of the PIV system regarding suitable test conditions and correct values of different adjustable PIV parameters. An additional objective was to gather CFD grade data for verification/validation of numerical models. Both water and steam injection tests were carried out. PIV measurements with cold water injection succeeded well. Raw images were of high quality, averaging over the whole measurement period could be done and flow fields close to the blowdown pipe outlet could be determined. In the warm water injection cases the obtained averaged velocity field images were harder to interpret, especially if the blowdown pipe was also filled with warm water in the beginning of the measurement period. The absolute values of the velocity vectors seemed to be smaller than in the cold water injection cases. With very small steam flow rates the steam/water interface was inside the blowdown pipe and quite stable in nature. The raw images were of good quality but due to some fluctuation in the velocity field averaging of the velocity images over the whole measured period couldn't be done. Condensation of steam in the vicinity of the pipe exit probably caused these fluctuations. A constant outflow was usually followed by a constant inflow towards the pipe exit. Vector field images corresponding to a certain phase of the test could be extracted and averaged but this would require a very careful analysis so that the images could be correctly categorized. With higher steam flow rates rapid condensation of large steam bubbles created small gas bubbles which were in front of the measurement area of the PIV system. They disturbed the measurements by reflecting laser light like seeding particles and therefore the raw images were of poor quality and they couldn't be

  12. Nuclear piping design, pipe support design and engineering during installation

    International Nuclear Information System (INIS)

    Podczerwinski, C.A.

    1983-01-01

    This paper discusses the computer-aided design of the piping and pipe supports of nuclear power plants. Hardware improvements have been made in the areas of man-machine communication, processing speed, and memory density. Topics considered include evolving design systems, application to current needs, safety-related small-bore piping and support design, as-built drawing review and reconciliation, large-bore pipe support design, snubber population reduction, and operating plant modifications. The improvements in man-machine communication hardware permit the designer to communicate with the computer in terms of pictures of elements of the design. The processing speed and memory density improvements enables the assembly of the design on the machine

  13. 49 CFR 192.55 - Steel pipe.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Steel pipe. 192.55 Section 192.55 Transportation... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Materials § 192.55 Steel pipe. (a) New steel pipe is... in accordance with paragraph (c) or (d) of this section. (b) Used steel pipe is qualified for use...

  14. 49 CFR 192.59 - Plastic pipe.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Plastic pipe. 192.59 Section 192.59 Transportation... BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Materials § 192.59 Plastic pipe. (a) New plastic pipe... specification; and (2) It is resistant to chemicals with which contact may be anticipated. (b) Used plastic pipe...

  15. 49 CFR 192.281 - Plastic pipe.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Plastic pipe. 192.281 Section 192.281... Plastic pipe. (a) General. A plastic pipe joint that is joined by solvent cement, adhesive, or heat fusion may not be disturbed until it has properly set. Plastic pipe may not be joined by a threaded joint or...

  16. Determination of the pipe stemming load

    International Nuclear Information System (INIS)

    Cowin, S.C.

    1979-01-01

    A mechanical model for the emplacement pipe system is developed. The model is then employed to determine the force applied to the surface collar of the emplacement pipe, the pipe-stemming load, and the stress along the emplacement pipe as a function of stemming height. These results are presented as integrals and a method for their numerical integration is given

  17. A GPR-protein interaction surface of Gi(alpha): implications for the mechanism of GDP-release inhibition.

    Science.gov (United States)

    Natochin, Michael; Gasimov, Karim G; Artemyev, Nikolai O

    2002-01-08

    Proteins containing G-protein regulatory (GPR) motifs represent a novel family of guanine nucleotide dissociation inhibitors (GDIs) for G(alpha) subunits from the Gi family. They selectively interact with the GDP-bound conformation of Gi(alpha) and transducin-alpha (Gt(alpha)), but not with Gs(alpha). A series of chimeric proteins between Gi(alpha)(1) and Gs(alpha) has been constructed to investigate GPR-contact sites on G(alpha) subunits and the mechanism of GPR-protein GDI activity. Analysis of the interaction of two GPR-proteins-AGS3GPR and Pcp2-with the chimeric G(alpha) subunits demonstrated that the GPR-Gi(alpha)(1) interface involves the Gi(alpha)(1) switch regions and Gi(alpha)(1)-144-151, a site within the helical domain. Residues within Gi(alpha)(1)-144-151 form conformation-sensitive contacts with switch III, and may directly interact with a GPR-protein or form a GPR-binding surface jointly with switch III. The helical domain site is critical to the ability of GPR-proteins to act as GDIs. Our data suggest that a mechanism of the GDI activity of GPR-proteins is different from that of GDIs for monomeric GTPases and from the GDI-like activity of G(betagamma) subunits. The GPR-proteins are likely to block a GDP-escape route on G(alpha) subunits.

  18. Increased expression of the proton-sensing G protein-coupled receptor Gpr65 during retinal degeneration.

    Science.gov (United States)

    Ail, D; Rüfenacht, V; Caprara, C; Samardzija, M; Kast, B; Grimm, C

    2015-08-20

    The retina is a metabolically highly active tissue that is sensitive to pH changes. Blinding diseases of the retina are often characterized by degeneration of photoreceptor cells altering the acid-base homeostasis of the tissue microenvironment and by an accompanying inflammatory response. GPR4, GPR65 and GPR68 are G protein-coupled receptors that aid cells to sense and survive conditions of acidic pH and inflammatory cells express Gpr65 enhancing their viability. Hence, we investigated expression and function of these proton-sensing GPRs in the normal and degenerating retina. We observed increased retinal expression of Gpr65, but not of Gpr4 and Gpr68, in mouse models of both inherited (rd10) and induced (light damage) retinal degeneration. Lack of GPR65 slightly accelerated photoreceptor degeneration in rd10 mice and resulted in a strong activation of microglia after light-injury. Since GPR65 was dispensable for normal retinal development, function and aging as evidenced by the evaluation of Gpr65(-/-) mice, our results indicate that the proton-sensing G protein-coupled receptor GPR65 may be involved in a mechanism that supports survival of photoreceptors in the degenerating retina. Copyright © 2015 IBRO. Published by Elsevier Ltd. All rights reserved.

  19. Evaluation of fracture toughness of nuclear piping using real pipe and tensile compact pipe specimens

    International Nuclear Information System (INIS)

    Koo, J.M.; Park, S.; Seok, C.S.

    2013-01-01

    Highlights: • The tensile compact pipe (CP) specimen was proposed. • J-integral for the specimen was obtained by the plastic limit load analysis and FEA. • Fracture toughness tests by several types of specimens were performed and compared. • The constraint effects were considered by comparing Q-stresses for them. -- Abstract: The leak-before-break (LBB) concept is generally used to design the primary heat transport piping for a nuclear power plant. The LBB concept is based on the fracture resistance curve, which is obtained by J–R tests on various types of specimens. Fracture toughness data differ according to the various types of specimens. It has also been known that there is a difference in the constraint effect between real pipes and standard specimens, and LBB design using standard specimens is conservative. We propose a new type of specimen for J–R tests, a tensile compact pipe (CP) specimen, and perform fracture toughness tests on various types of specimens. We also perform constraint effect analysis on such specimens. The Q-stresses of the tensile CP specimens are lower than those of real pipes under 4-point bending, and are higher than those of elbow pipes. If the lever length of a tensile CP specimen is controlled, the specimen can simulate various stress conditions, and it is thought that the LBB design of piping in service can be performed using this specimen

  20. Evaluation of fracture toughness of nuclear piping using real pipe and tensile compact pipe specimens

    Energy Technology Data Exchange (ETDEWEB)

    Koo, J.M.; Park, S.; Seok, C.S., E-mail: seok@skku.edu

    2013-06-15

    Highlights: • The tensile compact pipe (CP) specimen was proposed. • J-integral for the specimen was obtained by the plastic limit load analysis and FEA. • Fracture toughness tests by several types of specimens were performed and compared. • The constraint effects were considered by comparing Q-stresses for them. -- Abstract: The leak-before-break (LBB) concept is generally used to design the primary heat transport piping for a nuclear power plant. The LBB concept is based on the fracture resistance curve, which is obtained by J–R tests on various types of specimens. Fracture toughness data differ according to the various types of specimens. It has also been known that there is a difference in the constraint effect between real pipes and standard specimens, and LBB design using standard specimens is conservative. We propose a new type of specimen for J–R tests, a tensile compact pipe (CP) specimen, and perform fracture toughness tests on various types of specimens. We also perform constraint effect analysis on such specimens. The Q-stresses of the tensile CP specimens are lower than those of real pipes under 4-point bending, and are higher than those of elbow pipes. If the lever length of a tensile CP specimen is controlled, the specimen can simulate various stress conditions, and it is thought that the LBB design of piping in service can be performed using this specimen.

  1. G protein regulator 1 (GPR-1) localizes to cortical sites of artificial mechanical indentation in Caenorhabditis elegans zygotes.

    Science.gov (United States)

    Bringmann, Henrik

    2012-10-01

    Cytokinesis and spindle positioning require the cortical force regulator G Protein Regulator 1/2 (GPR-1/2). GPR-1/2 is thought to localize to sites of cortical force generation. Does GPR-1/2 also act as a sensor for mechanical stimulation? I mechanically stimulated the cortex by indenting it with a glass needle and observed the cortical localization of a YFP::GPR-1 transgene. I found that cortical YFP::GPR-1 accumulated at the site of mechanical indentation. This phenomenon occurred on most of the cortical areas except the site of prospective cytokinesis furrow formation. This result suggests that GPR-1/2 can sense mechanical properties of the cortex, which may be important for GPR-1/2 function regulating spindle positioning and cytokinesis. Copyright © 2012 Wiley Periodicals, Inc.

  2. U-rans model for the prediction of the acoustic sound power generated in a whistling corrugated pipe

    NARCIS (Netherlands)

    Golliard, J.; González Díez, N.; Belfroid, S.P.C.; Nakiboǧlu, G.; Hirschberg, A.

    2013-01-01

    Corrugated pipes, as used in flexible risers for gas production or in domestic appliances, can whistle when a flow is imposed through the pipe. Nakiboglu et al [1, 2] have developed a method to compute the acoustic source term for axi-symmetric cavities. The method is based on the resolution of

  3. 77 FR 19211 - Circular Welded Carbon-Quality Steel Pipe From the Socialist Republic of Vietnam: Preliminary...

    Science.gov (United States)

    2012-03-30

    ... the Brazilian, Korean, and Mexican orders on these products exclude ``Standard pipe that is dual or triple certified/stenciled that enters the U.S. as line pipe of a kind used for oil and gas pipelines... classifications while more recent proceedings on the product would not. Compare Countervailing Duty Order: Oil...

  4. Air–water flow in a vertical pipe : Experimental study of air bubbles in the vicinity of the wall

    NARCIS (Netherlands)

    Descamps, M.N.; Oliemans, R.V.A.; Ooms, G.; Mudde, R.F.

    2008-01-01

    This study deals with the influence of bubbles on a vertical air–water pipe flow, for gas-lift applications. The effect of changing the bubble size is of particular interest as it has been shown to affect the pressure drop over the pipe. Local measurements on the bubbles characteristics in the wall

  5. Selection of pipe repair methods.

    Science.gov (United States)

    2013-06-01

    The objective of this research is to provide pipeline operators with testing procedures and : results of the performance of composite pipe repair methods and ultimately, improve their : selection and installation, and reduce the risks associated with...

  6. Light pipes for LED measurements

    Science.gov (United States)

    Floyd, S. R.; Thomas, E. F., Jr.

    1976-01-01

    Light pipe directly couples LED optical output to single detector. Small area detector measures total optical output of diode. Technique eliminates thermal measurement problems and channels optical output to remote detector.

  7. Pulsating Heat Pipes, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Large radiator panels, based upon state of the art conventional heat pipes with attached fins for thermal load distribution and dissipation is the current baseline...

  8. Vision-Based Georeferencing of GPR in Urban Areas.

    Science.gov (United States)

    Barzaghi, Riccardo; Cazzaniga, Noemi Emanuela; Pagliari, Diana; Pinto, Livio

    2016-01-21

    Ground Penetrating Radar (GPR) surveying is widely used to gather accurate knowledge about the geometry and position of underground utilities. The sensor arrays need to be coupled to an accurate positioning system, like a geodetic-grade Global Navigation Satellite System (GNSS) device. However, in urban areas this approach is not always feasible because GNSS accuracy can be substantially degraded due to the presence of buildings, trees, tunnels, etc. In this work, a photogrammetric (vision-based) method for GPR georeferencing is presented. The method can be summarized in three main steps: tie point extraction from the images acquired during the survey, computation of approximate camera extrinsic parameters and finally a refinement of the parameter estimation using a rigorous implementation of the collinearity equations. A test under operational conditions is described, where accuracy of a few centimeters has been achieved. The results demonstrate that the solution was robust enough for recovering vehicle trajectories even in critical situations, such as poorly textured framed surfaces, short baselines, and low intersection angles.

  9. Delineating alluvial aquifer heterogeneity using resistivity and GPR data.

    Science.gov (United States)

    Bowling, Jerry C; Rodriguez, Antonio B; Harry, Dennis L; Zheng, Chunmiao

    2005-01-01

    Conceptual geological models based on geophysical data can elucidate aquifer architecture and heterogeneity at meter and smaller scales, which can lead to better predictions of preferential flow pathways. The macrodispersion experiment (MADE) site, with >2000 measurements of hydraulic conductivity obtained and three tracer tests conducted, serves as an ideal natural laboratory for examining relationships between subsurface flow characteristics and geophysical attributes in fluvial aquifers. The spatial variation of hydraulic conductivity measurements indicates a large degree of site heterogeneity. To evaluate the usefulness of geophysical methods for better delineating fluvial aquifer heterogeneities and distribution of preferential flow paths, a surface grid of two-dimensional ground penetrating radar (GPR) and direct current (DC) resistivity data were collected. A geological model was developed from these data that delineate four stratigraphic units with distinct electrical and radar properties including (from top to bottom) (1) a meandering fluvial system (MFS); (2) a braided fluvial system (BFS); (3) fine-grained sands; and (4) a clay-rich interval. A paleochannel, inferred by other authors to affect flow, was mapped in the MFS with both DC resistivity and GPR data. The channel is 2 to 4 m deep and, based on resistivity values, is predominantly filled with clay and silt. Comparing previously collected hydraulic conductivity measurements and tracer-plume migration patterns to the geological model indicates that flow primarily occurs in the BFS and that the channel mapped in the MFS has no influence on plume migration patterns.

  10. Multi-offset GPR methods for hyporheic zone investigations

    Science.gov (United States)

    Brosten, T.R.; Bradford, J.H.; McNamara, J.P.; Gooseff, M.N.; Zarnetske, J.P.; Bowden, W.B.; Johnston, M.E.

    2009-01-01

    Porosity of stream sediments has a direct effect on hyporheic exchange patterns and rates. Improved estimates of porosity heterogeneity will yield enhanced simulation of hyporheic exchange processes. Ground-penetrating radar (GPR) velocity measurements are strongly controlled by water content thus accurate measures of GPR velocity in saturated sediments provides estimates of porosity beneath stream channels using petrophysical relationships. Imaging the substream system using surface based reflection measurements is particularly challenging due to large velocity gradients that occur at the transition from open water to saturated sediments. The continuous multi-offset method improves the quality of subsurface images through stacking and provides measurements of vertical and lateral velocity distributions. We applied the continuous multi-offset method to stream sites on the North Slope, Alaska and the Sawtooth Mountains near Boise, Idaho, USA. From the continuous multi-offset data, we measure velocity using reflection tomography then estimate water content and porosity using the Topp equation. These values provide detailed measurements for improved stream channel hydraulic and thermal modelling. ?? 2009 European Association of Geoscientists & Engineers.

  11. Vision-Based Georeferencing of GPR in Urban Areas

    Directory of Open Access Journals (Sweden)

    Riccardo Barzaghi

    2016-01-01

    Full Text Available Ground Penetrating Radar (GPR surveying is widely used to gather accurate knowledge about the geometry and position of underground utilities. The sensor arrays need to be coupled to an accurate positioning system, like a geodetic-grade Global Navigation Satellite System (GNSS device. However, in urban areas this approach is not always feasible because GNSS accuracy can be substantially degraded due to the presence of buildings, trees, tunnels, etc. In this work, a photogrammetric (vision-based method for GPR georeferencing is presented. The method can be summarized in three main steps: tie point extraction from the images acquired during the survey, computation of approximate camera extrinsic parameters and finally a refinement of the parameter estimation using a rigorous implementation of the collinearity equations. A test under operational conditions is described, where accuracy of a few centimeters has been achieved. The results demonstrate that the solution was robust enough for recovering vehicle trajectories even in critical situations, such as poorly textured framed surfaces, short baselines, and low intersection angles.

  12. Mapping soil fractal dimension in agricultural fields with GPR

    Science.gov (United States)

    Oleschko, K.; Korvin, G.; Muñoz, A.; Velazquez, J.; Miranda, M. E.; Carreon, D.; Flores, L.; Martínez, M.; Velásquez-Valle, M.; Brambila, F.; Parrot, J.-F.; Ronquillo, G.

    2008-09-01

    We documented that the mapping of the fractal dimension of the backscattered Ground Penetrating Radar traces (Fractal Dimension Mapping, FDM) accomplished over heterogeneous agricultural fields gives statistically sound combined information about the spatial distribution of Andosol' dielectric permittivity, volumetric and gravimetric water content, bulk density, and mechanical resistance under seven different management systems. The roughness of the recorded traces was measured in terms of a single number H, the Hurst exponent, which integrates the competitive effects of volumetric water content, pore topology and mechanical resistance in space and time. We showed the suitability to combine the GPR traces fractal analysis with routine geostatistics (kriging) in order to map the spatial variation of soil properties by nondestructive techniques and to quantify precisely the differences under contrasting tillage systems. Three experimental plots with zero tillage and 33, 66 and 100% of crop residues imprinted the highest roughness to GPR wiggle traces (mean HR/S=0.15), significantly different to Andosol under conventional tillage (HR/S=0.47).

  13. Mapping soil fractal dimension in agricultural fields with GPR

    Directory of Open Access Journals (Sweden)

    K. Oleschko

    2008-09-01

    Full Text Available We documented that the mapping of the fractal dimension of the backscattered Ground Penetrating Radar traces (Fractal Dimension Mapping, FDM accomplished over heterogeneous agricultural fields gives statistically sound combined information about the spatial distribution of Andosol' dielectric permittivity, volumetric and gravimetric water content, bulk density, and mechanical resistance under seven different management systems. The roughness of the recorded traces was measured in terms of a single number H, the Hurst exponent, which integrates the competitive effects of volumetric water content, pore topology and mechanical resistance in space and time. We showed the suitability to combine the GPR traces fractal analysis with routine geostatistics (kriging in order to map the spatial variation of soil properties by nondestructive techniques and to quantify precisely the differences under contrasting tillage systems. Three experimental plots with zero tillage and 33, 66 and 100% of crop residues imprinted the highest roughness to GPR wiggle traces (mean HR/S=0.15, significantly different to Andosol under conventional tillage (HR/S=0.47.

  14. Combining orthogonal polarization for elongated target detection with GPR

    International Nuclear Information System (INIS)

    Lualdi, Maurizio; Lombardi, Federico

    2014-01-01

    For an accurate imaging of ground penetrating radar data the polarization characteristics of the propagating electromagnetic (EM) wavefield and wave amplitude variations with antenna pattern orientation must be taken into account. For objects that show some directionality feature and cylindrical shape any misalignment between transmitter and target can strongly modify the polarization state of the backscattered wavefield, thus conditioning the detection capability of the system. Hints on the depolarization can be used to design the optimal GPR antenna survey to avoid omissions and pitfalls during data processing. This research addresses the issue of elongated target detection through a multi azimuth (or multi polarization) approach based on the combination of mutually orthogonal GPR data. Results from the analysis of the formal scattering problem demonstrate how this strategy can reach a scalar formulation of the scattering matrix and achieve a rotational invariant quantity. The effectiveness of the algorithm is then evaluated with a detailed field example showing results closely proximal to those obtained under the optimal alignment condition: detection is significantly improved and the risk of target missing is reduced. (paper)

  15. Characterization of Accelerating Pipe Flow.

    Science.gov (United States)

    1988-03-01

    Journal of Chemical Engineering of Japan , vol...92, January 1970. 17. K. Kataoka, T. Kawabata, and K. Miki, "The Start-Up Response of Pipe Flow to a Step Change in Flow Rate," Journal of Chemical Engineering of Japan , vol...Pipe Flows," Journal of Chemical Engineering of Japan , vol. 9, no. 6, pp. 431-439, 1975. 19. E. van de Sande, A.P. Belde, B.J.G. Hamer, and W.

  16. Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor

    DEFF Research Database (Denmark)

    Hassing, H A; Engelstoft, M S; Sichlau, R M

    2016-01-01

    The intestinal G protein-coupled receptor GPR119 is a novel metabolic target involving glucagon-like peptide-1 (GLP-1)-derived insulin-regulated glucose homeostasis. Endogenous and diet-derived lipids, including N-acylethanolamines and 2-monoacylglycerols (2-MAG) activate GPR119. The purpose...... of this work is to evaluate whether 2-oleoyl glycerol (2-OG) improves glucose tolerance through GPR119, using wild type (WT) and GPR 119 knock out (KO) mice. We here show that GPR119 is essential for 2-OG-mediated release of GLP-1 and CCK from GLUTag cells, since a GPR119 specific antagonist completely...... abolished the hormone release. Similarly, in isolated primary colonic crypt cultures from WT mice, GPR119 was required for 2-OG-stimulated GLP-1 release while there was no response in crypts from KO mice. In vivo, gavage with 2-oleyl glyceryl ether ((2-OG ether), a stable 2-OG analog with a potency of 5.3 µ...

  17. Simulation for ground penetrating radar (GPR) study of the subsurface structure of the Moon

    Science.gov (United States)

    Fa, Wenzhe

    2013-12-01

    Ground penetrating radar (GPR) is currently within the scope of China's Chang-E 3 lunar mission, to study the shallow subsurface of the Moon. In this study, key factors that could affect a lunar GPR performance, such as frequency, range resolution, and antenna directivity, are discussed firstly. Geometrical optics and ray tracing techniques are used to model GPR echoes, considering the transmission, attenuation, reflection, geometrical spreading of radar waves, and the antenna directivity. The influence on A-scope GPR echoes and on the simulated radargrams for the Sinus Iridum region by surface and subsurface roughness, dielectric loss of the lunar regolith, radar frequency and bandwidth, and the distance between the transmit and receive antennas are discussed. Finally, potential scientific return about lunar subsurface properties from GPR echoes is also discussed. Simulation results suggest that subsurface structure from several to hundreds of meters can be studied from GPR echoes at P and VHF bands, and information about dielectric permittivity and thickness of subsurface layers can be estimated from GPR echoes in combination with regolith composition data.

  18. Activation of GPR15 and its involvement in the biological effects of smoking.

    Science.gov (United States)

    Kõks, Sulev; Kõks, Gea

    2017-06-01

    Smoking is one of the most significant modifiable environmental risk factors for many diseases. Smoking causes excessive mortality worldwide. Despite decades of long research, there has not been a clear understanding regarding the molecular mechanism that makes smoking harmful to health. Some recent studies have found that smoking influences most significantly the expression and methylation of GPR15. GPR15 is an orphan receptor that is involved in the regulation of the innate immunity and the T-cell trafficking in the intestinal epithelium. Further studies have confirmed that GPR15 is very strongly involved in smoking and smoking-induced molecular changes. Therefore, the altered expression and epigenetic regulation of GPR15 could have a significant role in the health impact of smoking. Impact statement The review describes an orphan receptor GPR15 that has recently been found to be influenced by smoking. This makes GPR15 very sensitive and adequate biomarker for smoking and smoking studies. Also, activation of GPR15 by smoking could help to explain its effects on health.

  19. Role of GPR30 in estrogen-induced prostate epithelial apoptosis and benign prostatic hyperplasia.

    Science.gov (United States)

    Yang, Deng-Liang; Xu, Jia-Wen; Zhu, Jian-Guo; Zhang, Yi-Lin; Xu, Jian-Bang; Sun, Qing; Cao, Xiao-Nian; Zuo, Wu-Lin; Xu, Ruo-Shui; Huang, Jie-Hong; Jiang, Fu-Neng; Zhuo, Yang-Jia; Xiao, Bai-Quan; Liu, Yun-Zhong; Yuan, Dong-Bo; Sun, Zhao-Lin; He, Hui-Chan; Lun, Zhao-Rong; Zhong, Wei-De; Zhou, Wen-Liang

    2017-06-03

    Several studies have implicated estrogen and the estrogen receptor (ER) in the pathogenesis of benign prostatic hyperplasia (BPH); however, the mechanism underlying this effect remains elusive. In the present study, we demonstrated that estrogen (17β-estradiol, or E2)-induced activation of the G protein-coupled receptor 30 (GPR30) triggered Ca 2+ release from the endoplasmic reticulum, increased the mitochondrial Ca 2+ concentration, and thus induced prostate epithelial cell (PEC) apoptosis. Both E2 and the GPR30-specific agonist G1 induced a transient intracellular Ca 2+ release in PECs via the phospholipase C (PLC)-inositol 1, 4, 5-triphosphate (IP 3 ) pathway, and this was abolished by treatment with the GPR30 antagonist G15. The release of cytochrome c and activation of caspase-3 in response to GPR30 activation were observed. Data generated from the analysis of animal models and human clinical samples indicate that treatment with the GPR30 agonist relieves testosterone propionate (TP)-induced prostatic epithelial hyperplasia, and that the abundance of GPR30 is negatively associated with prostate volume. On the basis of these results, we propose a novel regulatory mechanism whereby estrogen induces the apoptosis of PECs via GPR30 activation. Inhibition of this activation is predicted to lead to abnormal PEC accumulation, and to thereby contribute to BPH pathogenesis. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Holographic NDT methods for plastic pipe vibration and brittle crack propagation analysis

    Science.gov (United States)

    Markov, Vladimir B.; Boone, Pierre M.; Vanspeybroeck, Philippe

    1995-11-01

    Plastic pipes are frequently used for low pressure gas and water distribution. One of the main problems with their wide commercial applications is rapid crack propagation (RCP). This results in enormous losses of energy resources and environment pollution. Recent incidents show that it is of importance to find criteria to assess the safety conditions for large diameter piping before its installation. In this report some results of holographic non-destructive testing of plastic pipes are presented. Double-pulse holographic interferometry measurements of stress distribution at small scale steady state (S4) tests for 3 - 5 bar pressurized plastic pipes with (phi) 110 mm to 200 mm were performed. Also the mechanically induced vibration modes of non-pressurized (phi) 200 mm plastic pipe were visualized with the purpose to check stress distribution.

  1. Direct PTV study of powder suspension behind dune in a horizontal circular pipe

    Science.gov (United States)

    Yonezawa, Norio; Oishi, Yoshihiko; Tasaka, Yuji; Murai, Yuichi

    2014-04-01

    As small solid particles are mixed in gas flow in a horizontal pipe, the particles are sometimes long suspended downstream due to dynamic interaction between two phases in turbulent states. Dunes of such particles are naturally formed at the bottom of the pipe in case of heavy flow rate of particles, and the dunes rather help the particles with suspension further downstream. In this study, PTV has been applied for measurement of such particles floating inside a horizontal pipe behind a synthetic dune. Time-resolved PTV analysis of the particle behavior in the section perpendicular to the mainstream has revealed that long-suspended particles keep floating with fountain like convection pattern inside the circular pipe, which consists of ascending flow at the center of the pipe, bouncing flow at the wall, and downwash at the oblique part. The present paper shows their dynamic statistics of the particle behavior for the cross-sectional distributions of concentration, velocity vector, and acceleration vector.

  2. Numerical GPR Imaging through Directional Antenna Systems in Complex Scenarios

    Science.gov (United States)

    Comite, Davide; Murgia, Federica; Barbara, Martina; Catapano, Ilaria; Soldovieri, Francesco; Galli, Alessandro

    2017-04-01

    The capability of imaging hidden targets and interfaces in non-accessible and complex scenarios is a topic of increasing interest for several practical applications, such as civil engineering, geophysics, and planetary explorations [1]. In this frame, Ground Penetrating Radar (GPR) has been proven as an efficient and reliable technique, also thanks to the development of effective imaging procedures based on linear modeling of the scattering phenomenon, which is usually considered as activated by ideal sources [1],[2]. Actually, such modeling simplifications are rarely verified in typical operative scenarios, when a number of heterogeneous targets can interact each other and with the surrounding environment, producing undesired contributions such as clutter and ghosts targets. From a physical viewpoint, these phenomena are mainly due to multipath contributions at the receiving antenna system, and different solutions have been proposed to mitigate these effects on the final image reconstruction (see, e.g., [2] and references therein). In this work we investigate on the possible improvements achievable when the directional features of the transmitting antenna system are taken into account in the imaging algorithm. Following and extending the recent investigations illustrated in [2] and [3], we consider in particular arrays of antennas, made by arbitrary types of elements, as activating the scattering phenomenon: hence, the effects of neglecting or accounting for the inherent directional radiation of the considered array are investigated as regards the accuracy of the final reconstruction of targets. Taking into account the resolution losses linked to the relevant synthetic aperture, we analyze the possibility of improving the quality of imaging, mitigating the presence of spurious contributions. By implementing a 'synthetic setup' that analyzes the scenarios under test through different electromagnetic CAD tools (mainly CST Microwave Studio and gprMax), it has been

  3. Material characterization via in-situ GPR survey

    Science.gov (United States)

    D'Alterio, Antonietta; Solimene, Raffaele; Soldovieri, Francesco

    2010-05-01

    Ground Penetrating Radar (GPR) represents a feasible and friendly tool to gain information about the presence, location and geometry of targets embedded in opaque media. This is due to its advantages in terms of portability, easiness of use, fastness of the survey (it is possible to perform measurements over large areas in reduced time) and flexibility of employ. In this framework, it is largely employed in cultural heritage diagnostics with the aim of detecting hidden objects that can be representative of defects, voids or indicative of the constructive typology of the heritages. Despite of the widespread exploitation of the GPR as data acquisition system, the use of GPR reveals of limited usefulness in the case of complex scenarios as the case of masonries where the absence of any a priori information about them make difficult to obtain images reliable and easily interpretable by the end-users. Therefore, in order to gain information useful for a cultural heritage stakeholder, novel data processing approaches based on inverse scattering have been recently developed [1] These approaches are based on accurate electromagnetic scattering models and thanks to them, it is possible to gain accurate and reliable "images" of the investigated structure in order to detect, localize and possibly determine the extent and the geometrical features of the embedded objects. A crucial step to build up reliable inverse scattering models concerns with the determination of the background scenario with respect to the "defects" have to be detected and localised. From the electromagnetic point of view, it is necessary to have the maximum available information about the geometry of the structure (this can be also performed by historical sources) and about the materials employed in the construction of the structure. In fact, the knowledge of the materials permits to have an estimate of the electromagnetic properties of the materials that is necessary to build up reliable inverse

  4. Reliability analysis of stiff versus flexible piping

    International Nuclear Information System (INIS)

    Lu, S.C.

    1985-01-01

    The overall objective of this research project is to develop a technical basis for flexible piping designs which will improve piping reliability and minimize the use of pipe supports, snubbers, and pipe whip restraints. The current study was conducted to establish the necessary groundwork based on the piping reliability analysis. A confirmatory piping reliability assessment indicated that removing rigid supports and snubbers tends to either improve or affect very little the piping reliability. The authors then investigated a couple of changes to be implemented in Regulatory Guide (RG) 1.61 and RG 1.122 aimed at more flexible piping design. They concluded that these changes substantially reduce calculated piping responses and allow piping redesigns with significant reduction in number of supports and snubbers without violating ASME code requirements. Furthermore, the more flexible piping redesigns are capable of exhibiting reliability levels equal to or higher than the original stiffer design. An investigation of the malfunction of pipe whip restraints confirmed that the malfunction introduced higher thermal stresses and tended to reduce the overall piping reliability. Finally, support and component reliabilities were evaluated based on available fragility data. Results indicated that the support reliability usually exhibits a moderate decrease as the piping flexibility increases. Most on-line pumps and valves showed an insignificant reduction in reliability for a more flexible piping design

  5. Development of Intelligent pipe Locator

    Energy Technology Data Exchange (ETDEWEB)

    Miyamoto, Yukinori

    1987-09-10

    As the cities gets denser, development of a pipe locator, which can easily detect the position of the complicatedly buried underground pipes with high accuracy, is greatly demanded. A newly developed intelligent pipe locator detects a magnetic field generated by flowing an alternating-current through a buried pipe by means of a sensor unit placed on the ground and by computing and displaying with a micro-computer the position, depth, and the reliability of the detected result in only 3 seconds. Results of a half year field test since Sept. 1986 shows that the error was improved twice up to 5% from 10% of the conventional pipe locator. Operation time was also reduced down to one-fifth of the former method. By the practical use of this locator on the spot, one can expect the security improvements, reduction of frilling cost, and more efficient operation. In Japan recently, the number of conventional pipe locator is more than 5000 units in about 15 types. (10 figs, 7 tabs)

  6. Design of a low cost miniaturized SFCW GPR with initial results

    Science.gov (United States)

    Duggal, Swati; Sinha, Piyush; Gupta, Manish; Patel, Anand; Vedam, V. V.; Mevada, Pratik; Chavda, Rajesh; Shah, Amita; Putrevu, Deepak

    2016-05-01

    This paper discusses about the design &developmental of Ground Penetrating Radar (GPR), various scientific and commercial applications of GPR along with the testing and results of GPR at Antarctica for Ice thickness measurement. GPR instruments are categorised as per their frequency of operation, which is inversely proportional to the depth of penetration. GPRs are also categorized as per method of operation which is time-domain or frequency-domain. Indian market is presently procuring GPRs from only foreign suppliers. Space Applications Centre (SAC) had taken up GPR as R&D Technological development with a view to benchmark the technology which may be transferred to local industry for mass production of instrument at a relatively cheaper cost (~20 times cheaper). Hence, this instrument presents a viable indigenous alternative. Also, the design and configuration was targeted for terrestrial as well as future interplanetary (Lander/Rover) missions of ISRO to map subsurface features. The developed GPR has a very large bandwidth (100%, i.e. bandwidth of 500MHz with centre-frequency of 500MHz) and high dynamic range along with the advantage of being highly portable (<10kg). The system was configured as a Stepped-Frequency-Continuous-Wave (SFCW) GPR which is a frequency domain GPR with the aim to increase the detection capabilities with respect to current systems. In order to achieve this goal, innovative electronic equipment have been designed and developed. Three prototypes were developed and two of them have been delivered for Indian Scientific Expedition to Antarctica (ISEA) in 2013 and 2014-15, respectively and promising results have been obtained. The results from the same closely compare with that from commercial GPR too.

  7. GPR40 reduces food intake and body weight through GLP-1.

    Science.gov (United States)

    Gorski, Judith N; Pachanski, Michele J; Mane, Joel; Plummer, Christopher W; Souza, Sarah; Thomas-Fowlkes, Brande S; Ogawa, Aimie M; Weinglass, Adam B; Di Salvo, Jerry; Cheewatrakoolpong, Boonlert; Howard, Andrew D; Colletti, Steven L; Trujillo, Maria E

    2017-07-01

    G protein-coupled receptor 40 (GPR40) partial agonists lower glucose through the potentiation of glucose-stimulated insulin secretion, which is believed to provide significant glucose lowering without the weight gain or hypoglycemic risk associated with exogenous insulin or glucose-independent insulin secretagogues. The class of small-molecule GPR40 modulators, known as AgoPAMs (agonist also capable of acting as positive allosteric modulators), differentiate from partial agonists, binding to a distinct site and functioning as full agonists to stimulate the secretion of both insulin and glucagon-like peptide-1 (GLP-1). Here we show that GPR40 AgoPAMs significantly increase active GLP-1 levels and reduce acute and chronic food intake and body weight in diet-induced obese (DIO) mice. These effects of AgoPAM treatment on food intake are novel and required both GPR40 and GLP-1 receptor signaling pathways, as demonstrated in GPR40 and GLP-1 receptor-null mice. Furthermore, weight loss associated with GPR40 AgoPAMs was accompanied by a significant reduction in gastric motility in these DIO mice. Chronic treatment with a GPR40 AgoPAM, in combination with a dipeptidyl peptidase IV inhibitor, synergistically decreased food intake and body weight in the mouse. The effect of GPR40 AgoPAMs on GLP-1 secretion was recapitulated in lean, healthy rhesus macaque demonstrating that the putative mechanism mediating weight loss translates to higher species. Together, our data indicate effects of AgoPAMs that go beyond glucose lowering previously observed with GPR40 partial agonist treatment with additional potential for weight loss. Copyright © 2017 the American Physiological Society.

  8. Leaks in pipe networks

    Science.gov (United States)

    Pudar, Ranko S.; Liggett, James A.

    1992-01-01

    Leak detection in water-distribution systems can be accomplished by solving an inverse problem using measurements of pressure and/or flow. The problem is formulated with equivalent orifice areas of possible leaks as the unknowns. Minimization of the difference between measured and calculated heads produces a solution for the areas. The quality of the result depends on number and location of the measurements. A sensitivity matrix is key to deciding where to make measurements. Both location and magnitude of leaks are sensitive to the quantity and quality of pressure measurements and to how well the pipe friction parameters are known. The overdetermined problem (more measurements than suspected leaks) gives the best results, but some information can be derived from the underdetermined problem. The variance of leak areas, based on the quality of system characteristics and pressure data, indicates the likely accuracy of the results. The method will not substitute for more traditional leak surveys but can serve as a guide and supplement.

  9. Piping inspection round robin

    International Nuclear Information System (INIS)

    Heasler, P.G.; Doctor, S.R.

    1996-04-01

    The piping inspection round robin was conducted in 1981 at the Pacific Northwest National Laboratory (PNNL) to quantify the capability of ultrasonics for inservice inspection and to address some aspects of reliability for this type of nondestructive evaluation (NDE). The round robin measured the crack detection capabilities of seven field inspection teams who employed procedures that met or exceeded the 1977 edition through the 1978 addenda of the American Society of Mechanical Engineers (ASME) Section 11 Code requirements. Three different types of materials were employed in the study (cast stainless steel, clad ferritic, and wrought stainless steel), and two different types of flaws were implanted into the specimens (intergranular stress corrosion cracks (IGSCCs) and thermal fatigue cracks (TFCs)). When considering near-side inspection, far-side inspection, and false call rate, the overall performance was found to be best in clad ferritic, less effective in wrought stainless steel and the worst in cast stainless steel. Depth sizing performance showed little correlation with the true crack depths

  10. Targeting CB2-GPR55 Receptor Heteromers Modulates Cancer Cell Signaling*

    Science.gov (United States)

    Moreno, Estefanía; Andradas, Clara; Medrano, Mireia; Caffarel, María M.; Pérez-Gómez, Eduardo; Blasco-Benito, Sandra; Gómez-Cañas, María; Pazos, M. Ruth; Irving, Andrew J.; Lluís, Carme; Canela, Enric I.; Fernández-Ruiz, Javier; Guzmán, Manuel; McCormick, Peter J.; Sánchez, Cristina

    2014-01-01

    The G protein-coupled receptors CB2 (CB2R) and GPR55 are overexpressed in cancer cells and human tumors. Because a modulation of GPR55 activity by cannabinoids has been suggested, we analyzed whether this receptor participates in cannabinoid effects on cancer cells. Here we show that CB2R and GPR55 form heteromers in cancer cells, that these structures possess unique signaling properties, and that modulation of these heteromers can modify the antitumoral activity of cannabinoids in vivo. These findings unveil the existence of previously unknown signaling platforms that help explain the complex behavior of cannabinoids and may constitute new targets for therapeutic intervention in oncology. PMID:24942731

  11. Some examples of GPR prospecting for monitoring of the monumental heritage

    International Nuclear Information System (INIS)

    Masini, Nicola; Persico, Raffaele; Rizzo, Enzo

    2010-01-01

    In this paper three case histories of ground penetrating radar (GPR) for the monitoring of historical buildings are presented. They aim to present the specific valence of the GPR in the field of the diagnostic of historical buildings, which is a promising field of research, due to the increasing awareness of the relevance (even economic) of the cultural heritage. The presented GPR prospecting cases have been performed on three different constructive elements typical of historical buildings (a wall, a masonry pillar and a marble column) in order to be the answer to different problems such as the characterization of the masonry, the detection of cracks and the imaging of metallic reinforcement bars

  12. GPR Image and Signal Processing for Pavement and Road Monitoring on Android Smartphones and Tablets

    Science.gov (United States)

    Benedetto, Francesco; Benedetto, Andrea; Tedeschi, Antonio

    2014-05-01

    Ground Penetrating Radar (GPR) is a geophysical method that uses radar pulses to image the subsurface. This non-destructive method uses electromagnetic radiation and detects the reflected signals from subsurface structures. It can detect objects, changes in material, and voids and cracks. GPR has many applications in a number of fields. In the field of civil engineering one of the most advanced technologies used for road pavement monitoring is based on the deployment of advanced GPR systems. One of the most relevant causes of road pavement damage is often referable to water intrusion in structural layers. In this context, GPR has been recently proposed as a method to estimate moisture content in a porous medium without preventive calibration. Hence, the development of methods to obtain an estimate of the moisture content is a crucial research field involving economic, social and strategic aspects in road safety for a great number of public and private Agencies. In particular, a recent new approach was proposed to estimate moisture content in a porous medium basing on the theory of Rayleigh scattering, showing a shift of the frequency peak of the GPR spectrum towards lower frequencies as the moisture content increases in the soil. Addressing some of these issues, this work proposes a mobile application, for smartphones and tablets, for GPR image and signal processing. Our application has been designed for the Android mobile operating system, since it is open source and android mobile platforms are selling the most smartphones in the world (2013). The GPR map can be displayed in black/white or color and the user can zoom and navigate into the image. The map can be loaded in two different ways: from the local memory of the portable device or from a remote server. This latter possibility can be very useful for real-time and mobile monitoring of road and pavement inspection. In addition, the application allows analyzing the GPR data also in the frequency domain. It is

  13. Accelerated life tests of specimen heat pipe from Communication Technology Satellite (CTS) project

    Science.gov (United States)

    Tower, L. K.; Kaufman, W. B.

    1977-01-01

    A gas-loaded variable conductance heat pipe of stainless steel with methanol working fluid identical to one now on the CTS satellite was life tested in the laboratory at accelerated conditions for 14 200 hours, equivalent to about 70 000 hours at flight conditions. The noncondensible gas inventory increased about 20 percent over the original charge. The observed gas increase is estimated to increase operating temperature by about 2.2 C, insufficient to harm the electronic gear cooled by the heat pipes in the satellite. Tests of maximum heat input against evaporator elevation agree well with the manufacturer's predictions.

  14. NEP heat pipe radiators. [Nuclear Electric Propulsion

    Science.gov (United States)

    Ernst, D. M.

    1979-01-01

    This paper covers improvements of heat pipe radiators for the thermionic NEP design. Liquid metal heat pipes are suitable as spacecraft radiator elements because of high thermal conductance, low mass and reliability, but the NEP thermionic system design was too large and difficult to fabricate. The current integral collector-radiator design consisting of several layers of thermionic converters, the annular-tangential collector heat pipe, the radiator heat pipe, and the transition zone designed to minimize the temperature difference between the collector heat pipe and radiator heat pipe are described. Finally, the design of micrometeoroid armor protection and the fabrication of the stainless steel annular heat pipe with a tangential arm are discussed, and it is concluded that the heat rejection system for the thermionic NEP system is well advanced, but the collector-radiator heat pipe transition and the 8 to 10 m radiator heat pipe with two bends require evaluation.

  15. CODIFICATION OF FIBER REINFORCED COMPOSITE PIPING

    Energy Technology Data Exchange (ETDEWEB)

    Rawls, G.

    2012-10-10

    The goal of the overall project is to successfully adapt spoolable FRP currently used in the oil industry for use in hydrogen pipelines. The use of FRP materials for hydrogen service will rely on the demonstrated compatibility of these materials for pipeline service environments and operating conditions. The ability of the polymer piping to withstand degradation while in service, and development of the tools and data required for life management are imperative for successful implementation of these materials for hydrogen pipeline. The information and data provided in this report provides the technical basis for the codification for fiber reinforced piping (FRP) for hydrogen service. The DOE has invested in the evaluation of FRP for the delivery for gaseous hydrogen to support the development of a hydrogen infrastructure. The codification plan calls for detailed investigation of the following areas: System design and applicable codes and standards; Service degradation of FRP; Flaw tolerance and flaw detection; Integrity management plan; Leak detection and operational controls evaluation; Repair evaluation. The FRP codification process started with commercially available products that had extensive use in the oil and gas industry. These products have been evaluated to assure that sufficient structural integrity is available for a gaseous hydrogen environment.

  16. Removal of a long PVC pipe strangulated in the penis by hot-melt method.

    Science.gov (United States)

    Jiatao, Ji; Bin, Xu; Huamao, Ye; Jianguo, Hou; Bing, Liu; Yinghao, Sun

    2011-02-01

    Penile incarceration for erotic or autoerotic purposes has been reported in a wide range of age groups, and often presents a significant challenge to urologic surgeons. No ready method has been reported for removing a polyvinylchloride (PVC) pipe entrapped on the penis. To present our experience in using hot-melt method to remove a constricted PVC pipe on the penis. A long melting split was made on the PVC pipe entrapped on the penis by using the long narrow branch of forceps heated on a gas stove. The heated forceps was able to make a melt split on the PVC pipe. Consequently, the PVC pipe was removed by pulling the edges of the pipe apart without much difficulty. The total operation time was 20 minutes. Penile incarceration is a urologic emergency, for which resourcefulness is required in some unexpected cases. Hot-melting has proved to be an easy and effective method for removing penile strangulation by a PVC pipe. To our knowledge, it is the first report about the removal of PVC pipe entrapped on a penis. © 2010 International Society for Sexual Medicine.

  17. Mechanism for in-pipe inspection; Dispositivo para inspecao de dutos

    Energy Technology Data Exchange (ETDEWEB)

    Freitas, Gustavo Medeiros; Dutra, Max Suell [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil)

    2008-07-01

    The internal inspection of pipes is becoming a routine activity thanks to their importance on transportation of substances such as oil and natural gas. This paper addresses a mechanism capable of working inside pipes of different diameters that may present extreme curves and inclinations. The mechanism is composed of modules with devices that provide adjustable contact with the duct, using wheels on the contact points. The robot moves inside the pipe creating a virtual spindle. For that, two parts are used: the first one, guided along the pipe by a set of wheels, moves parallel to the axis of the pipe; the second part is attached to a motor. The motor rotation forces the mechanism to follow a helical motion, with tilted wheels rotating about the axis of the pipe. Each adjustable contact device works like a lever, pressing the wheel against the pipe. The base of the device can be actively rotated, modifying the angle of the wheel in relation to the pipe (equivalent to the step of the spindle), permitting the motion of the system in both directions, with specific velocity. According to the applied angle, the robot changes the relation between torque and displacement velocity. (author)

  18. The effect of cyclic and dynamic loads on carbon steel pipe

    International Nuclear Information System (INIS)

    Rudland, D.L.; Scott, P.M.; Wilkowski, G.M.

    1996-02-01

    This report presents the results of four 152-mm (6-inch) diameter, unpressurized, circumferential through-wall-cracked, dynamic pipe experiments fabricated from STS410 carbon steel pipe manufactured in Japan. For three of these experiments, the through-wall crack was in the base metal. The displacement histories applied to these experiments were a quasi-static monotonic, dynamic monotonic, and dynamic, cyclic (R = -1) history. The through-wall crack for the third experiment was in a tungsten-inert-gas weld, fabricated in Japan, joining two lengths of STS410 pipe. The displacement history for this experiment was the same history applied to the dynamic, cyclic base metal experiment. The test temperature for each experiment was 300 C (572 F). The objective of these experiments was to compare a Japanese carbon steel pipe material with US pipe material, to ascertain whether this Japanese steel was as sensitive to dynamic and cyclic effects as US carbon steel pipe. In support of these pipe experiments, quasi-static and dynamic, tensile and fracture toughness tests were conducted. An analysis effort was performed that involved comparing experimental crack initiation and maximum moments with predictions based on available fracture prediction models, and calculating J-R curves for the pipe experiments using the η-factor method

  19. Synthesis, pharmacological characterization, and structure-activity relationship studies of small molecular agonists for the orphan GPR88 receptor.

    Science.gov (United States)

    Jin, Chunyang; Decker, Ann M; Huang, Xi-Ping; Gilmour, Brian P; Blough, Bruce E; Roth, Bryan L; Hu, Yang; Gill, Joseph B; Zhang, X Peter

    2014-07-16

    GPR88 is an orphan G-protein-coupled receptor (GPCR) enriched in the striatum. Genetic deletion and gene expression studies have suggested that GPR88 plays an important role in the regulation of striatal functions and is implicated in psychiatric disorders. The signal transduction pathway and receptor functions of GPR88, however, are still largely unknown due to the lack of endogenous and synthetic ligands. In this paper, we report the synthesis of a GPR88 agonist 2-PCCA and its pure diastereomers, which were functionally characterized in both transiently and stably expressing GPR88 HEK293 cells. 2-PCCA inhibited isoproterenol-stimulated cAMP accumulation in a concentration-dependent manner in cells expressing GPR88 but not in the control cells, suggesting that the observed cAMP inhibition is mediated through GPR88 and that GPR88 is coupled to Gαi. 2-PCCA did not induce calcium mobilization in GPR88 cells, indicating no Gαq-mediated response. A structure-activity relationship (SAR) study of 2-PCCA was also conducted to explore the key structural features for GPR88 agonist activity.

  20. TSTA Piping and Flame Arrestor Operating Experience Data

    Energy Technology Data Exchange (ETDEWEB)

    Cadwallader, Lee C.; Willms, R. Scott

    2014-10-01

    The Tritium Systems Test Assembly (TSTA) was a facility dedicated to tritium handling technology and experiment research at the Los Alamos National Laboratory. The facility operated from 1984 to 2001, running a prototype fusion fuel processing loop with ~100 grams of tritium as well as small experiments. There have been several operating experience reports written on this facility’s operation and maintenance experience. This paper describes analysis of two additional components from TSTA, small diameter gas piping that handled small amounts of tritium in a nitrogen carrier gas, and the flame arrestor used in this piping system. The operating experiences and the component failure rates for these components are discussed in this paper. Comparison data from other applications are also presented.

  1. Pipe robots for internal inspection, non-destructive testing and machining of pipelines

    International Nuclear Information System (INIS)

    Reiss, Alexander

    2016-01-01

    Inspector Systems is a specialist in manufacturing of tethered self-propelled pipe robots for internal inspection, non-destructive testing and machining of pipeline systems. Our industrial sectors, which originates from 30 year experience in the nuclear industry, are Gas and Oil (On-/Offshore, Refineries), Chemical, Petrochemical, Water etc. The pipe robots are able to get inserted through poor access points (e.g. valves) and to pass in bi-directional travelling vertical sections and numerous bends with small arc radius. The paper describes the system concept and performance of the pipe robot technology. A modular construction allows to equip the robots with different operational elements for the respective application.

  2. Influence of physical aging on impact embrittlement of uPVC pipes

    OpenAIRE

    Visser, Roy; Bor, Teunis Cornelis; Wolters, Mannes; Warnet, Laurent; Govaert, L.E.

    2011-01-01

    Most failures of unplasticised poly(vinyl chloride) (uPVC) pipes used in the Dutch gas distribution network originate from third party damage. Brittle pipes should therefore be replaced to ensure safe operation of the network. In this study, the relation between physical aging and embrittlement of uPVC is investigated using instrumented falling weight impact tests. The ductile to brittle transition temperature was first measured for a water pipe grade uPVC at different stages of aging. As a h...

  3. GPR in shallow subsurface studies: case Umbozero mine

    Science.gov (United States)

    Kupila, Juho; Johansson, Peter; Kivilompolo, Janne; Pihlaja, Jouni; Väisänen, Ulpu; Konukhin, Vladimir; Kozyrev, Anatoly; Alakangas, Lena

    2014-05-01

    Geophysical methods, including ground penetrating radar, can play an important role in dynamic field studies. In this case study, GPR was used to determine characteristics and thickness of the soil and conditions of groundwater and also to find out the possible locations of the faults and other major structures in bedrock under the thin (1-5 meters) layers of soil. Studies were carried out in the area of Umbozero mine site, which is located in the north-western part of Russia, in the western slopes of Lovozero alkaline massive. The underground mine was closed in 2004. Field studies were executed in several periods in 2012 and 2013 with Finnish, Russian and Swedish experts. Studies also included soil and water sampling for collecting new data from the closed mine site to improve the methods of the mine closure process. GPR survey was focused on two different types of areas: the tailings pond and the wide slope area above the underground mine. At the tailings, the survey was also made along the dam to find out the original structure of the dam. The instrument used was Swedish Malå ProEx with 100MHz antenna, which proved to be accurate enough with sufficient range of depth. XY-location of the profiles was sharp, but without more specific elevation data, the vertical level was more or less relative. Results of the survey varied, depending on the measured area. On the tailings pond, layers of imported material were thick and mostly saturated with groundwater, and the texture of the material was partly very fine-grained. Thus the penetration of the GPR pulse was poor and it was not possible to reach the original level of the ground surface with this method. However, some structures and general outlook of the material can be seen from the profiles. Above the underground mine, where soil layer cover was only 1-5 meters and material mostly coarse, dry moraine, thickness and structure of soil and some structures of the bedrock surface were clearly interpretable

  4. Study on production mechanism of welding residual stress at the juncture of a pipe penetrating a thick plate

    International Nuclear Information System (INIS)

    Mochizuki, Masahito; Enomoto, Kunio; Okamoto, Noriaki; Saitoh, Hideyo; Hayashi, Eisaku.

    1994-01-01

    This paper studies welding residual stresses at the intersection of a small diameter pipe penetrating a thick plate. The pipe is welded to the plate, and Tungsten Innert Gas (TIG) cladding is melted on the inner surface of the pipe to protect it from stress corrosion cracking due to long operation in nuclear power plants. Stresses are calculated by heat conduction analysis and thermal elasto-plastic analysis, and also measured by strain gauges. Welding residual stresses are shown to have no corrosive influence on the inner pipe surface, and the stresses are compressed enough to protect the pipe against stress corrosion cracking on the outer surface. It was also studied to make clear the production mechanism of the residual stresses which were generated by welding processes at the pipe. (author)

  5. Characterisation of carbonate rocks from near-surface cross-hole and reflection GPR investigations - A case study from southeast Zealand, Denmark

    Science.gov (United States)

    Nielsen, Lars; Looms, Majken C.; Hansen, Thomas M.; Cordua, Knud S.; Stemmerik, Lars

    2010-05-01

    cross-hole data is regarded as the same type of medium. Modelling strategies in which porosity data from the boreholes are included in the inversion algorithm are tested and compared to the results obtained using the more traditional approaches. The GPR investigations may contribute to setting the framework for future fine-grained models designed to simulate fluid and gas flow in groundwater and hydrocarbon reservoirs.

  6. Design of a Novel In-Pipe Reliable Leak Detector

    OpenAIRE

    Chatzigeorgiou, Dimitrios; Youcef-Toumi, Kamal; Ben-Mansour, Rached

    2013-01-01

    Leakage is the major factor for unaccounted losses in every pipe network around the world (oil, gas, or water). In most cases, the deleterious effects associated with the occurrence of leaks may present serious economical and health problems. Therefore, leaks must be quickly detected, located, and repaired. Unfortunately, most state-of-the-art leak detection systems have limited applicability, are neither reliable nor robust, while others depend on the user experience. In this paper, we prese...

  7. Development and Manufacture of Cost-Effective Composite Drill Pipe

    Energy Technology Data Exchange (ETDEWEB)

    James C. Leslie

    2008-12-31

    Advanced Composite Products and Technology, Inc. (ACPT) has developed composite drill pipe (CDP) that matches the structural and strength properties of steel drill pipe, but weighs less than 50 percent of its steel counterpart. Funding for the multiyear research and development of CDP was provided by the U.S. Department of Energy Office of Fossil Energy through the Natural Gas and Oil Projects Management Division at the National Energy Technology Laboratory (NETL). Composite materials made of carbon fibers and epoxy resin offer mechanical properties comparable to steel at less than half the weight. Composite drill pipe consists of a composite material tube with standard drill pipe steel box and pin connections. Unlike metal drill pipe, composite drill pipe can be easily designed, ordered, and produced to meet specific requirements for specific applications. Because it uses standard joint connectors, CDP can be used in lieu of any part of or for the entire steel drill pipe section. For low curvature extended reach, deep directional drilling, or ultra deep onshore or offshore drilling, the increased strength to weight ratio of CDP will increase the limits in all three drilling applications. Deceased weight will reduce hauling costs and increase the amount of drill pipe allowed on offshore platforms. In extreme extended reach areas and high-angle directional drilling, drilling limits are associated with both high angle (fatigue) and frictional effects resulting from the combination of high angle curvature and/or total weight. The radius of curvature for a hole as small as 40 feet (12.2 meters) or a build rate of 140 degrees per 100 feet is within the fatigue limits of specially designed CDP. Other properties that can be incorporated into the design and manufacture of composite drill pipe and make it attractive for specific applications are corrosion resistance, non-magnetic intervals, and abrasion resistance coatings. Since CDP has little or no electromagnetic force

  8. Flow induced vibrations of piping

    International Nuclear Information System (INIS)

    Gibert, R.J.; Axisa, F.

    1977-01-01

    In order to design the supports of piping systems, estimations of the vibrations induced by the fluid conveyed through the pipes are generally needed. For that purpose it is necessary to calculate the model parameters of liquid containing pipes. In most computer codes, fluid effects are accounted for just by adding the fuid mass to the structure. This may lead to serious errors.- Inertial effects from the fluid are not correctly evaluated especially in the case of bended or of non-uniform section pipes. Fluid boundary conditions are simply ignored. - In many practical problems fluid compressibility cannot be negelcted, even in the low frequencies domain which corresponds to efficient excitation by turbulent sources of the flow. This paper presents a method to take into account these efects, by solving a coupled mechanical acoustical problem: the computer code TEDEL of the C.E.A./D.E.M.T. System, based on the finite-elements method, has been extended to calculate simultaneously the pressure fluctuations in the fluid and the vibrations of the pipe. (Auth.)

  9. Microcomputer generated pipe support calculations

    International Nuclear Information System (INIS)

    Hankinson, R.F.; Czarnowski, P.; Roemer, R.E.

    1991-01-01

    The cost and complexity of pipe support design has been a continuing challenge to the construction and modification of commercial nuclear facilities. Typically, pipe support design or qualification projects have required large numbers of engineers centrally located with access to mainframe computer facilities. Much engineering time has been spent repetitively performing a sequence of tasks to address complex design criteria and consolidating the results of calculations into documentation packages in accordance with strict quality requirements. The continuing challenges of cost and quality, the need for support engineering services at operating plant sites, and the substantial recent advances in microcomputer systems suggested that a stand-alone microcomputer pipe support calculation generator was feasible and had become a necessity for providing cost-effective and high quality pipe support engineering services to the industry. This paper outlines the preparation for, and the development of, an integrated pipe support design/evaluation software system which maintains all computer programs in the same environment, minimizes manual performance of standard or repetitive tasks, and generates a high quality calculation which is consistent and easily followed

  10. Flexible ultrasonic pipe inspection apparatus

    Science.gov (United States)

    Jenkins, C.F.; Howard, B.D.

    1998-06-23

    A flexible, modular ultrasonic pipe inspection apparatus, comprises a flexible, hollow shaft that carries a plurality of modules, including at least one rotatable ultrasonic transducer, a motor/gear unit, and a position/signal encoder. The modules are connected by flexible knuckle joints that allow each module of the apparatus to change its relative orientation with respect to a neighboring module, while the shaft protects electrical wiring from kinking or buckling while the apparatus moves around a tight corner. The apparatus is moved through a pipe by any suitable means, including a tether or drawstring attached to the nose or tail, differential hydraulic pressure, or a pipe pig. The rotational speed of the ultrasonic transducer and the forward velocity of the apparatus are coordinated so that the beam sweeps out the entire interior surface of the pipe, enabling the operator to accurately assess the condition of the pipe wall and determine whether or not leak-prone corrosion damage is present. 7 figs.

  11. Flow induced vibrations of piping

    International Nuclear Information System (INIS)

    Gibert, R.J.; Axisa, F.

    1977-01-01

    This paper presents a method to take into account the inertial effects and the fluid compressibility by solving a coupled mechanical-acoustical problem: the computer code TEDEL of the C.E.A./D.E.M.T. System, based on the finite-element method, has been extended to calculate simultaneously the pressure fluctuations in the fluid and the vibrations of the pipe. By this way the mechanical-acoustical coupled eigenmodes of any piping system can be obtained. These eigenmodes are used to determine the response of the system to various sources (acoustical sources or forces exciting directly the structure). Equations have been written in the hypothesis that acoustical wave lengths remain large compared to the diameter of the pipe. Indeed this is largely verified in almost practical cases. The method has been checked by an experiment performed on the GASCOGNE loop at D.E.M.T. The piping system under test consist of a tube with four elbows. The circuit is ended at each extremity by a large vessel which performs acoustical isolation by generating modes for the pressure. Excitation of the circuit is caused by a valve located near the downstream vessel. This provide an efficient localised broad band acoustical source. The comparison between the test results and the calculations has shown that the low frequency resonant characteristics of the pipe and the vibrational amplitude at various flow-rates can be correctly predicted [fr

  12. Effective implementation of GPR for condition assessment and monitoring - Phase 2.

    Science.gov (United States)

    2016-10-01

    The Maryland Department of Transportation State Highway Administration (SHA) is currently using Ground : Penetrating Radar (GPR) for assessing the condition of bridge decks (such as surface condition, rebar cover depth : and location, and deck thickn...

  13. Effective implementation of GPR for condition assessment and monitoring - phase 2 : final report.

    Science.gov (United States)

    2016-10-01

    The Maryland Department of Transportation State Highway Administration (SHA) is currently using Ground Penetrating Radar (GPR) for assessing the condition of bridge decks (such as surface condition, rebar cover depth and location, and deck thickness)...

  14. The orphan G protein-coupled receptor GPR139 is activated by the peptides

    DEFF Research Database (Denmark)

    Jensen, Anne Cathrine Nøhr; Shehata, Mohamed A; Hauser, Alexander S

    2017-01-01

    GPR139 is an orphan G protein-coupled receptor that is expressed primarily in the brain. Not much is known regarding the function of GPR139. Recently we have shown that GPR139 is activated by the amino acids l-tryptophan and l-phenylalanine (EC50 values of 220 μM and 320 μM, respectively), as well...... cleavage site in the pre-pro-protein pro-opiomelanocortin (POMC). Our results demonstrate that GPR139 is a peptide receptor, activated by ACTH, α-MSH, β-MSH, the conserved core motif HFRW as well as a potential endogenous peptide α-MSH1-9. Further studies are needed to determine the functional relevance...

  15. Clay content evaluation in soils through GPR signal processing

    Science.gov (United States)

    Tosti, Fabio; Patriarca, Claudio; Slob, Evert; Benedetto, Andrea; Lambot, Sébastien

    2013-10-01

    The mechanical behavior of soils is partly affected by their clay content, which arises some important issues in many fields of employment, such as civil and environmental engineering, geology, and agriculture. This work focuses on pavement engineering, although the method applies to other fields of interest. Clay content in bearing courses of road pavement frequently causes damages and defects (e.g., cracks, deformations, and ruts). Therefore, the road safety and operability decreases, directly affecting the increase of expected accidents. In this study, different ground-penetrating radar (GPR) methods and techniques were used to non-destructively investigate the clay content in sub-asphalt compacted soils. Experimental layout provided the use of typical road materials, employed for road bearing courses construction. Three types of soils classified by the American Association of State Highway and Transportation Officials (AASHTO) as A1, A2, and A3 were used and adequately compacted in electrically and hydraulically isolated test boxes. Percentages of bentonite clay were gradually added, ranging from 2% to 25% by weight. Analyses were carried out for each clay content using two different GPR instruments. A pulse radar with ground-coupled antennae at 500 MHz centre frequency and a vector network analyzer spanning the 1-3 GHz frequency range were used. Signals were processed in both time and frequency domains, and the consistency of results was validated by the Rayleigh scattering method, the full-waveform inversion, and the signal picking techniques. Promising results were obtained for the detection of clay content affecting the bearing capacity of sub-asphalt layers.

  16. Structural basis for regulation of GPR56/ADGRG1 by its alternatively spliced extracellular domains

    OpenAIRE

    Salzman, Gabriel S.; Ackerman, Sarah D.; Ding, Chen; Koide, Akiko; Leon, Katherine; Luo, Rong; Stoveken, Hannah M.; Fernandez, Celia G.; Tall, Gregory G.; Piao, Xianhua; Monk, Kelly R.; Koide, Shohei; Araç, Demet

    2016-01-01

    Adhesion G-protein-coupled receptors (aGPCRs) play critical roles in diverse neurobiological processes including brain development, synaptogenesis, and myelination. aGPCRs have large alternatively spliced extracellular regions (ECRs) that likely mediate intercellular signaling; however, the precise roles of ECRs remain unclear. The aGPCR GPR56/ADGRG1 regulates both oligodendrocyte and cortical development. Accordingly, human GPR56 mutations cause myelination defects and brain malformations. H...

  17. Modeling of GPR of the rock massif of placer deposits with faults in the cryolithozone

    Science.gov (United States)

    Struchkov, Alexander S.

    2017-11-01

    The experience of using the gprMax GPR system is shown to determine the features of the radiophysical characteristics of signals reflected from faults. It is found that the traditional methods of determining boundaries on the radargram can not detect the presence of such faults. According to the results of the modeling, it is established that the method developed by the author for automatically determining the boundaries of geological environments on the radargram successfully finds these areas.

  18. Altered metabolism in the melatonin-related receptor (GPR50) knockout mouse.

    Science.gov (United States)

    Ivanova, Elena A; Bechtold, David A; Dupré, Sandrine M; Brennand, John; Barrett, Perry; Luckman, Simon M; Loudon, Andrew S I

    2008-01-01

    The X-linked orphan receptor GPR50 shares 45% homology with the melatonin receptors, yet its ligand and physiological function remain unknown. Here we report that mice lacking functional GPR50 through insertion of a lacZ gene into the coding sequence of GPR50 exhibit an altered metabolic phenotype. GPR50 knockout mice maintained on normal chow exhibit lower body weight than age-matched wild-type littermates by 10 wk of age. Furthermore, knockout mice were partially resistant to diet-induced obesity. When placed on a high-energy diet (HED) for 5 wk, knockout mice consumed significantly more food per unit body weight yet exhibited an attenuated weight gain and reduced body fat content compared with wild-type mice. Wheel-running activity records revealed that, although GPR50 knockout mice showed no alteration of circadian period, the overall levels of activity were significantly increased over wild types in both nocturnal and diurnal phases. In line with this, basal metabolic rate (O2 consumption, CO2 production, and respiratory quotient) was found to be elevated in knockout mice. Using in situ hybridization (wild-type mice) and beta-galactosidase activity (from LacZ insertion element in knockout mice), brain expression of GPR50 was found to be restricted to the ependymal layer of the third ventricle and dorsomedial nucleus of the hypothalamus. GPR50 expression was highly responsive to energy status, showing a significantly reduced expression following both fasting and 5 wk of HED. These data implicate GPR50 as an important regulator of energy metabolism.

  19. Analyses of GPR signals for characterization of ground conditions in urban areas

    Science.gov (United States)

    Hong, Won-Taek; Kang, Seonghun; Lee, Sung Jin; Lee, Jong-Sub

    2018-05-01

    Ground penetrating radar (GPR) is applied for the characterization of the ground conditions in urban areas. In addition, time domain reflectometry (TDR) and dynamic cone penetrometer (DCP) tests are conducted for the accurate analyses of the GPR images. The GPR images are acquired near a ground excavation site, where a ground subsidence occurred and was repaired. Moreover, the relative permittivity and dynamic cone penetration index (DCPI) are profiled through the TDR and DCP tests, respectively. As the ground in the urban area is kept under a low-moisture condition, the relative permittivity, which is inversely related to the electromagnetic impedance, is mainly affected by the dry density and is inversely proportional to the DCPI value. Because the first strong signal in the GPR image is shifted 180° from the emitted signal, the polarity of the electromagnetic wave reflected at the dense layer, where the reflection coefficient is negative, is identical to that of the first strong signal. The temporal-scaled GPR images can be accurately converted into the spatial-scaled GPR images using the relative permittivity determined by the TDR test. The distribution of the loose layer can be accurately estimated by using the spatial-scaled GPR images and reflection characteristics of the electromagnetic wave. Note that the loose layer distribution estimated in this study matches well with the DCPI profile and is visually verified from the endoscopic images. This study demonstrates that the GPR survey complemented by the TDR and DCP tests, may be an effective method for the characterization of ground conditions in an urban area.

  20. GPR119 Agonist AS1269574 Activates TRPA1 Cation Channels to Stimulate GLP-1 Secretion.

    Science.gov (United States)

    Chepurny, Oleg G; Holz, George G; Roe, Michael W; Leech, Colin A

    2016-06-01

    GPR119 is a G protein-coupled receptor expressed on intestinal L cells that synthesize and secrete the blood glucose-lowering hormone glucagon-like peptide-1 (GLP-1). GPR119 agonists stimulate the release of GLP-1 from L cells, and for this reason there is interest in their potential use as a new treatment for type 2 diabetes mellitus. AS1269574 is one such GPR119 agonist, and it is the prototype of a series of 2,4,6 trisubstituted pyrimidines that exert positive glucoregulatory actions in mice. Here we report the unexpected finding that AS1269574 stimulates GLP-1 release from the STC-1 intestinal cell line by directly promoting Ca(2+) influx through transient receptor potential ankyrin 1 (TRPA1) cation channels. These GPR119-independent actions of AS1269574 are inhibited by TRPA1 channel blockers (AP-18, A967079, HC030031) and are not secondary to intracellular Ca(2+) release or cAMP production. Patch clamp studies reveal that AS1269574 activates an outwardly rectifying membrane current with properties expected of TRPA1 channels. However, the TRPA1 channel-mediated action of AS1269574 to increase intracellular free calcium concentration is not replicated by GPR119 agonists (AR231453, oleoylethanolamide) unrelated in structure to AS1269574. Using human embryonic kidney-293 cells expressing recombinant rat TRPA1 channels but not GPR119, direct TRPA1 channel activating properties of AS1269574 are validated. Because we find that AS1269574 also acts in a conventional GPR119-mediated manner to stimulate proglucagon gene promoter activity in the GLUTag intestinal L cell line, new findings reported here reveal the surprising capacity of AS1269574 to act as a dual agonist at two molecular targets (GPR119/TRPA1) important to the control of L-cell function and type 2 diabetes mellitus drug discovery research.

  1. 75 FR 38781 - Certain Large Diameter Carbon and Alloy Seamless Standard, Line, and Pressure Pipe From Japan...

    Science.gov (United States)

    2010-07-06

    ... conveyance of water, steam, natural gas, air and other liquids and gasses in plumbing and heating systems... line applications such as oil, gas, or water pipeline, or utility distribution systems. Seamless..., natural gas and other liquids and gasses in industrial piping systems. They may carry these substances at...

  2. Pipe Lines – External Corrosion

    Directory of Open Access Journals (Sweden)

    Dan Babor

    2008-01-01

    Full Text Available Two areas of corrosion occur in pipe lines: corrosion from the medium carried inside the pipes; corrosion attack upon the outside of the pipes (underground corrosion. Electrolytic processes are also involved in underground corrosion. Here the moisture content of the soil acts as an electrolyte, and the ions required to conduct the current are supplied by water-soluble salts (chlorides, sulfates, etc. present in the soil. The nature and amount of these soluble materials can vary within a wide range, which is seen from the varying electrical conductivity and pH (varies between 3 and 10. Therefore the characteristics of a soil will be an important factor in under-ground corrosion.

  3. Regulating the effects of GPR21, a novel target for type 2 diabetes

    Science.gov (United States)

    Leonard, Siobhán; Kinsella, Gemma K.; Benetti, Elisa; Findlay, John B. C.

    2016-05-01

    Type 2 diabetes is a chronic metabolic disorder primarily caused by insulin resistance to which obesity is a major contributor. Expression levels of an orphan G protein-coupled receptor (GPCR), GPR21, demonstrated a trend towards a significant increase in the epididymal fat pads of wild type high fat high sugar (HFHS)-fed mice. To gain further insight into the potential role this novel target may play in the development of obesity-associated type 2 diabetes, the signalling capabilities of the receptor were investigated. Overexpression studies in HEK293T cells revealed GPR21 to be a constitutively active receptor, which couples to Gαq type G proteins leading to the activation of mitogen activated protein kinases (MAPKs). Overexpression of GPR21 in vitro also markedly attenuated insulin signalling. Interestingly, the effect of GPR21 on the MAPKs and insulin signalling was reduced in the presence of serum, inferring the possibility of a native inhibitory ligand. Homology modelling and ligand docking studies led to the identification of a novel compound that inhibited GPR21 activity. Its effects offer potential as an anti-diabetic pharmacological strategy as it was found to counteract the influence of GPR21 on the insulin signalling pathway.

  4. GPR30 mediates anorectic estrogen-induced STAT3 signaling in the hypothalamus.

    Science.gov (United States)

    Kwon, Obin; Kang, Eun Seok; Kim, Insook; Shin, Sora; Kim, Mijung; Kwon, Somin; Oh, So Ra; Ahn, Young Soo; Kim, Chul Hoon

    2014-11-01

    Estrogen plays an important role in the control of energy balance in the hypothalamus. Leptin-independent STAT3 activation (i.e., tyrosine(705)-phosphorylation of STAT3, pSTAT3) in the hypothalamus is hypothesized as the primary mechanism of the estrogen-induced anorexic response. However, the type of estrogen receptor that mediates this regulation is unknown. We investigated the role of the G protein-coupled receptor 30 (GPR30) in estradiol (E2)-induced STAT3 activation in the hypothalamus. Regulation of STAT3 activation by E2, G-1, a specific agonist of GPR30 and G-15, a specific antagonist of GPR30 was analyzed in vitro and in vivo. Effect of GPR30 activation on eating behavior was analyzed in vivo. E2 stimulated pSTAT3 in cells expressing GPR30, but not expressing estrogen receptor ERα and ERβ. G-1 induced pSTAT3, and G-15 inhibited E2-induced pSTAT3 in primary cultures of hypothalamic neurons. A cerebroventricular injection of G-1 increased pSTAT3 in the arcuate nucleus of mice, which was associated with a decrease in food intake and body weight gain. These results suggest that GPR30 is the estrogen receptor that mediates the anorectic effect of estrogen through the STAT3 pathway in the hypothalamus. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. GPR124 Functions as a WNT7-Specific Coactivator of Canonical β-Catenin Signaling

    Directory of Open Access Journals (Sweden)

    Ekaterina Posokhova

    2015-01-01

    Full Text Available G protein-coupled receptor 124 (GPR124 is an orphan receptor in the adhesion family of GPCRs, and previous global or endothelial-specific disruption of Gpr124 in mice led to defective CNS angiogenesis and blood-brain barriergenesis. Similar developmental defects were observed following dual deletion of Wnt7a/Wnt7b or deletion of β-catenin in endothelial cells, suggesting a possible relationship between GPR124 and canonical WNT signaling. Here, we show using in vitro reporter assays, mutation analysis, and genetic interaction studies in vivo that GPR124 functions as a WNT7A/WNT7B-specific costimulator of β-catenin signaling in brain endothelium. WNT7-stimulated β-catenin signaling was dependent upon GPR124’s intracellular PDZ binding motif and a set of leucine-rich repeats in its extracellular domain. This study reveals a vital role for GPR124 in potentiation of WNT7-induced canonical β-catenin signaling with important implications for understanding and manipulating CNS-specific angiogenesis and blood-brain barriergenesis.

  6. Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Jun; Byrne, Noel; Wang, John; Bricogne, Gerard; Brown, Frank K.; Chobanian, Harry R.; Colletti, Steven L.; Di Salvo, Jerry; Thomas-Fowlkes, Brande; Guo, Yan; Hall, Dawn L.; Hadix, Jennifer; Hastings, Nicholas B.; Hermes, Jeffrey D.; Ho, Thu; Howard, Andrew D.; Josien, Hubert; Kornienko, Maria; Lumb, Kevin J.; Miller, Michael W.; Patel, Sangita B.; Pio, Barbara; Plummer, Christopher W.; Sherborne, Bradley S.; Sheth, Payal; Souza, Sarah; Tummala, Srivanya; Vonrhein, Clemens; Webb, Maria; Allen, Samantha J.; Johnston, Jennifer M.; Weinglass, Adam B.; Sharma, Sujata; Soisson, Stephen M. (Merck); (Globel Phasing)

    2017-06-05

    Clinical studies indicate that partial agonists of the G-protein-coupled, free fatty acid receptor 1 GPR40 enhance glucose-dependent insulin secretion and represent a potential mechanism for the treatment of type 2 diabetes mellitus. Full allosteric agonists (AgoPAMs) of GPR40 bind to a site distinct from partial agonists and can provide additional efficacy. We report the 3.2-Å crystal structure of human GPR40 (hGPR40) in complex with both the partial agonist MK-8666 and an AgoPAM, which exposes a novel lipid-facing AgoPAM-binding pocket outside the transmembrane helical bundle. Comparison with an additional 2.2-Å structure of the hGPR40–MK-8666 binary complex reveals an induced-fit conformational coupling between the partial agonist and AgoPAM binding sites, involving rearrangements of the transmembrane helices 4 and 5 (TM4 and TM5) and transition of the intracellular loop 2 (ICL2) into a short helix. These conformational changes likely prime GPR40 to a more active-like state and explain the binding cooperativity between these ligands.

  7. Frequency of the GPR7 Tyr135Phe allelic variant in lean and obese subjects.

    Science.gov (United States)

    Pelosini, C; Maffei, M; Ceccarini, G; Marchi, M; Marsili, A; Galli, G; Scartabelli, G; Tamberi, A; Latrofa, F; Fierabracci, P; Vitti, P; Pinchera, A; Santini, F

    2013-10-01

    GPR7, the endogenous coupled receptor for neuropeptide B and neuropeptide W, is expressed in several regions of the central nervous system, which are involved in the regulation of feeding behavior. GPR7 affects the regulation of energy balance through a mechanism independent of leptin and melanocortin pathways. Aim of this study was to investigate whether GPR7 gene mutations can be detected in human subjects and, in that event, if they are differently distributed among lean and obese subjects. The coding region of GPR7 were sequenced in 150 obese patients and 100 normal-weight unrelated controls. Functional studies of the allelic variants were performed. One genetic GPR7 variant was found (Tyr135Phe - rs33977775) in obese subjects (13.3%) and lean control (25%). Functional studies did not reveal significant differences between the wild type and the Tyr135Phe allelic variants in their NPW-mediated capacity to inhibit forskolin-induced cAMP production. Screening of GPR7 gene mutations among lean and obese subjects revealed a Tyr135Phe allelic variant that was fairly common in the study population. As indicated by in vitro and in silico studies, this variant is unlikely to cause a functional derangement of the receptor.

  8. GPR56/ADGRG1 Inhibits Mesenchymal Differentiation and Radioresistance in Glioblastoma.

    Science.gov (United States)

    Moreno, Marta; Pedrosa, Leire; Paré, Laia; Pineda, Estela; Bejarano, Leire; Martínez, Josefina; Balasubramaniyan, Veerakumar; Ezhilarasan, Ravesanker; Kallarackal, Naveen; Kim, Sung-Hak; Wang, Jia; Audia, Alessandra; Conroy, Siobhan; Marin, Mercedes; Ribalta, Teresa; Pujol, Teresa; Herreros, Antoni; Tortosa, Avelina; Mira, Helena; Alonso, Marta M; Gómez-Manzano, Candelaria; Graus, Francesc; Sulman, Erik P; Piao, Xianhua; Nakano, Ichiro; Prat, Aleix; Bhat, Krishna P; de la Iglesia, Núria

    2017-11-21

    A mesenchymal transition occurs both during the natural evolution of glioblastoma (GBM) and in response to therapy. Here, we report that the adhesion G-protein-coupled receptor, GPR56/ADGRG1, inhibits GBM mesenchymal differentiation and radioresistance. GPR56 is enriched in proneural and classical GBMs and is lost during their transition toward a mesenchymal subtype. GPR56 loss of function promotes mesenchymal differentiation and radioresistance of glioma initiating cells both in vitro and in vivo. Accordingly, a low GPR56-associated signature is prognostic of a poor outcome in GBM patients even within non-G-CIMP GBMs. Mechanistically, we reveal GPR56 as an inhibitor of the nuclear factor kappa B (NF-κB) signaling pathway, thereby providing the rationale by which this receptor prevents mesenchymal differentiation and radioresistance. A pan-cancer analysis suggests that GPR56 might be an inhibitor of the mesenchymal transition across multiple tumor types beyond GBM. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

  9. IMF-Slices for GPR Data Processing Using Variational Mode Decomposition Method

    Directory of Open Access Journals (Sweden)

    Xuebing Zhang

    2018-03-01

    Full Text Available Using traditional time-frequency analysis methods, it is possible to delineate the time-frequency structures of ground-penetrating radar (GPR data. A series of applications based on time-frequency analysis were proposed for the GPR data processing and imaging. With respect to signal processing, GPR data are typically non-stationary, which limits the applications of these methods moving forward. Empirical mode decomposition (EMD provides alternative solutions with a fresh perspective. With EMD, GPR data are decomposed into a set of sub-components, i.e., the intrinsic mode functions (IMFs. However, the mode-mixing effect may also bring some negatives. To utilize the IMFs’ benefits, and avoid the negatives of the EMD, we introduce a new decomposition scheme termed variational mode decomposition (VMD for GPR data processing for imaging. Based on the decomposition results of the VMD, we propose a new method which we refer as “the IMF-slice”. In the proposed method, the IMFs are generated by the VMD trace by trace, and then each IMF is sorted and recorded into different profiles (i.e., the IMF-slices according to its center frequency. Using IMF-slices, the GPR data can be divided into several IMF-slices, each of which delineates a main vibration mode, and some subsurface layers and geophysical events can be identified more clearly. The effectiveness of the proposed method is tested using synthetic benchmark signals, laboratory data and the field dataset.

  10. Potential roles of GPR120 and its agonists in the management of diabetes

    Directory of Open Access Journals (Sweden)

    Zhang D

    2014-07-01

    Full Text Available Dan Zhang, Po Sing Leung School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Abstract: Free fatty acids (FFAs serve not only as nutrients that provide energy but also as extracellular signaling molecules that manipulate intracellular physiological events through FFA receptors (FFARs such as FFAR4. FFAR4 is also known as G-protein coupled receptor 120 (GPR120. The main role of GPR120 is to elicit FFA regulation on metabolism homeostasis. GPR120 agonism correlates with prevention of the occurrence and development of metabolic disorders such as obesity and diabetes. GPR120 activation directly or indirectly inhibits inflammation, modulates hormone secretion from the gastrointestinal tract and pancreas, and regulates lipid and/or glucose metabolism in adipose, liver, and muscle tissues, which may help prevent obesity and diabetes. This review summarizes recent advances in physiological roles of GPR120 in preventing insulin resistance and protecting pancreatic islet function, and examines how resident GPR120 in the pancreas may be involved in modulating pancreatic islet function. Keywords: fatty acid, G protein-coupled receptors, inflammation, pancreas, obesity

  11. Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity.

    Science.gov (United States)

    Cui, Jing; Ding, Yi; Chen, Shu; Zhu, Xiaoqiang; Wu, Yichen; Zhang, Mingliang; Zhao, Yaxin; Li, Tong-Ruei R; Sun, Ling V; Zhao, Shimin; Zhuang, Yuan; Jia, Weiping; Xue, Lei; Han, Min; Xu, Tian; Wu, Xiaohui

    2016-09-01

    A rise in the occurrence of obesity has driven exploration of its underlying genetic basis and potential targets for intervention. GWAS studies have identified obesity susceptibility pathways involving several neuropeptides that control energy homeostasis, suggesting that variations in the genes that regulate food intake and energy expenditure may contribute to obesity. In this study, we identified 5 additional obesity loci, including a neuronal orphan GPCR called Gpr45, in a forward genetic screen of mutant mice generated by piggyBac insertional mutagenesis. Disruption of Gpr45 led to increased adiposity at the time of weaning and increases in body mass, fat content, glucose intolerance, and hepatic steatosis with advancing age. Mice with disruptions in Gpr45 also displayed a reduction in expression of the metabolic regulator POMC and less energy expenditure prior to the onset of obesity. Mechanistically, we determined that GPR45 regulates POMC expression via the JAK/STAT pathway in a cell-autonomous manner. Consistent with this finding, intraventricular administration of melanotan-2, an analog of the POMC derivative α-MSH, suppressed adult obesity in Gpr45 mutants. These results reveal that GPR45 is a regulator of POMC signaling and energy expenditure, which suggests that it may be a potential intervention target to combat obesity.

  12. Nuclear piping design - An overview

    International Nuclear Information System (INIS)

    Pattabiraman, J.; Neelwarne, A.

    1993-01-01

    Nuclear piping design is a continuously evolving process. Advances in analytical tools and the experience gained from the behaviour of structural systems under normal operating and extreme events like earthquake provide necessary inputs for refinement of design procedures/practices to achieve more economical and safe designs. Although, during last two decades considerable improvements in analytical tools were achieved, an overemphasis on providing conservatism in seismic design resulting in non optimal designs still remains. Present paper discusses aspects such as reliability and maintainability in the context of existing codal requirements of nuclear piping. The uncertainty associated with magnitude of seismic events, their damage potential in combination with other operational piping loads and lack of reliable data during 1970's were contributing factors for building conservatism in the seismic design rules/procedures. However, present status of research and experience on performance of above ground piping systems indicate that the damage potential of seismic event has been considerably overestimated and that overstiff designs have been adopted which have drawbacks in satisfying flexibility criteria for normal operations. The optimal design in the context of nuclear piping, therefore, should imply safe and trouble free operation throughout the life of plant with adequate margins provided for sustaining postulated seismic events. Though conformity with ASME code provides basic protection against piping failure, the issues related with reliability and maintainability, crucial for continued safe operation, can be best addressed through a rational design strategy. Such a design strategy should be based on careful evaluation of various loads related to their damage potential and impact on overall safety margins

  13. Investigation of the GPR39 zinc receptor following inhibition of monoaminergic neurotransmission and potentialization of glutamatergic neurotransmission

    DEFF Research Database (Denmark)

    Młyniec, Katarzyna; Gaweł, Magdalena; Librowski, Tadeusz

    2015-01-01

    Zinc can regulate neural function in the brain via the GPR39 receptor. In the present study we investigated whether inhibition of serotonin, noradrenaline and dopamine synthesis and potentialization of glutamate, via administration of p-chlorophenylalanine (pCPA), α-methyl-p-tyrosine (αMT) and N......-methyl-d-aspartatic acid (NMDA), respectively, would cause changes in GPR39 levels. Western blot analysis showed GPR39 up-regulation following 3-day administration of αMT and NMDA in the frontal cortex, and GPR39 down-regulation following 10-day administration of pCPA, αMT, and NMDA in the hippocampus of CD-1 mice....... There were no changes in serum zinc levels. Additionally, we investigated tryptophan, tyrosine and glutamate concentrations in the hippocampus and frontal cortex of GPR39 knockout (GPR39 KO) mice. Liquid chromatography-mass spectrometry (LC-MS) showed a significant decrease in tryptophan and tyrosine...

  14. The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells

    Directory of Open Access Journals (Sweden)

    Gin-Wen Chang

    2016-05-01

    Full Text Available Natural killer (NK cells possess potent cytotoxic mechanisms that need to be tightly controlled. Here, we explored the regulation and function of GPR56/ADGRG1, an adhesion G protein-coupled receptor implicated in developmental processes and expressed distinctively in mature NK cells. Expression of GPR56 was triggered by Hobit (a homolog of Blimp-1 in T cells and declined upon cell activation. Through studying NK cells from polymicrogyria patients with disease-causing mutations in ADGRG1, encoding GPR56, and NK-92 cells ectopically expressing the receptor, we found that GPR56 negatively regulates immediate effector functions, including production of inflammatory cytokines and cytolytic proteins, degranulation, and target cell killing. GPR56 pursues this activity by associating with the tetraspanin CD81. We conclude that GPR56 inhibits natural cytotoxicity of human NK cells.

  15. GPR39 splice variants versus antisense gene LYPD1: expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue

    DEFF Research Database (Denmark)

    Egerod, Kristoffer L; Holst, Birgitte; Petersen, Pia S

    2007-01-01

    five-transmembrane form, GPR39-1b. The 3' exon of the GPR39 gene overlaps with an antisense gene called LYPD1 (Ly-6/PLAUR domain containing 1). Quantitative RT-PCR analysis demonstrated that GPR39-1a is expressed selectively throughout the gastrointestinal tract, including the liver and pancreas...... important for the expression of GPR39. In vivo experiments in rats demonstrated that GPR39 is up-regulated in adipose tissue during fasting and in response to streptozotocin treatment, although its expression is kept constant in the liver from the same animals. GPR39-1a was expressed in white but not brown...

  16. High performance flexible heat pipes

    Science.gov (United States)

    Shaubach, R. M.; Gernert, N. J.

    1985-01-01

    A Phase I SBIR NASA program for developing and demonstrating high-performance flexible heat pipes for use in the thermal management of spacecraft is examined. The program combines several technologies such as flexible screen arteries and high-performance circumferential distribution wicks within an envelope which is flexible in the adiabatic heat transport zone. The first six months of work during which the Phase I contract goal were met, are described. Consideration is given to the heat-pipe performance requirements. A preliminary evaluation shows that the power requirement for Phase II of the program is 30.5 kilowatt meters at an operating temperature from 0 to 100 C.

  17. Piping Inelastic Fracture Mechanics Analysis.

    Science.gov (United States)

    1980-06-30

    120 160 200 2410 280 320 2 (DEGREES) Fig. 16-Comparison on limit moment predictions with experimental rcsults- AISI 304 piping property data. For...1975, cracks were discovered on many 4 in. diameter 304 s.s. pipes for recirculation loop valve bypass, and on 10 in. diameter 304 s.s. reactor core...LOCATIONd THERM4AL SLEEVE REPAIR WELD TYPE 310 STAINLESS TEL C FVICt AREA SPO PCE Fig. 3.1-Duane Arnold recirculation-inlet-nozzle safe end configuration

  18. Seismic design of piping systems

    International Nuclear Information System (INIS)

    Anglaret, G.; Beguin, J.L.

    1986-01-01

    This paper deals with the method used in France for the PWR nuclear plants to derive locations and types of supports of auxiliary and secondary piping systems taking earthquake in account. The successive steps of design are described, then the seismic computation method and its particular conditions of applications for piping are presented. The different types of support (and especially seismic ones) are described and also their conditions of installation. The method used to compare functional tests results and computation results in order to control models is mentioned. Some experiments realised on site or in laboratory, in order to validate models and methods, are presented [fr

  19. Laboratory exercises on oscillation modes of pipes

    Science.gov (United States)

    Haeberli, Willy

    2009-03-01

    This paper describes an improved lab setup to study the vibrations of air columns in pipes. Features of the setup include transparent pipes which reveal the position of a movable microphone inside the pipe; excitation of pipe modes with a miniature microphone placed to allow access to the microphone stem for open, closed, or conical pipes; and sound insulation to avoid interference between different setups in a student lab. The suggested experiments on the modes of open, closed, and conical pipes, the transient response of a pipe, and the effect of pipe diameter are suitable for introductory physics laboratories, including laboratories for nonscience majors and music students, and for more advanced undergraduate laboratories. For honors students or for advanced laboratory exercises, the quantitative relation between the resonance width and damping time constant is of interest.

  20. Corrosion of Spiral Rib Aluminized Pipe

    Science.gov (United States)

    2012-08-01

    Large diameter, corrugated steel pipes are a common sight in the culverts that run alongside many Florida roads. Spiral-ribbed aluminized pipe (SRAP) has been widely specified by the Florida Department of Transportation (FDOT) for runoff drainage. Th...